WorldWideScience

Sample records for degenerate critical points

  1. Streamline topologies near simple degenerate critical points in two-dimensional flow away from boundaries

    DEFF Research Database (Denmark)

    Brøns, Morten; Hartnack, Johan Nicolai

    1999-01-01

    changes results in a much simplified system of differential equations for the streamlines (a normal form) encapsulating all the features of the original system. From this, we obtain a complete description of bifurcations up to codimension three close to a simple linear degeneracy. As a special case we......Streamline patterns and their bifurcations in two-dimensional incompressible flow are investigated from a topological point of view. The velocity field is expanded at a point in the fluid, and the expansion coefficients are considered as bifurcation parameters. A series of nonlinear coordinate...... develop the theory for flows with reflectional symmetry. We show that all the patterns obtained can be realized in steady Navier–Stokes or Stokes flow, but an unresolved difficulty arises in the symmetric case for Navier–Stokes flow. The theory is applied to the patterns and bifurcations found numerically...

  2. Streamline topologies near simple degenerate critical points in two-dimensional flow away from boundaries

    DEFF Research Database (Denmark)

    Brøns, Morten; Hartnack, Johan Nicolai

    1998-01-01

    changes results in a much simplified system of differential equations for the streamlines (a normal form) encapsulating all the features of the original system. From this, we obtain a complete description of bifurcations up to codimension three close to a simple linear degeneracy. As a special case we......Streamline patterns and their bifurcations in two-dimensional incompressible flow are investigated from a topological point of view. The velocity field is expanded at a point in the fluid, and the expansion coefficients are considered as bifurcation parameters. A series of non-linear coordinate...... develop the theory for flows with reflectional symmetry. We show that all the patterns obtained can be realized in steady Navier-Stokes or Stokes flow, but an unresolved difficulty arises in the symmetric case for Navier-Stokes flow. The theory is applied to the patterns and bifurcations found numerically...

  3. Magnonic triply-degenerate nodal points

    Science.gov (United States)

    Owerre, S. A.

    2017-12-01

    We generalize the concept of triply-degenerate nodal points to non-collinear antiferromagnets. Here, we introduce this concept to insulating quantum antiferromagnets on the decorated honeycomb lattice, with spin-1 bosonic quasiparticle excitations known as magnons. We demonstrate the existence of magnonic surface states with constant energy contours that form pairs of magnonic arcs connecting the surface projection of the magnonic triple nodal points. The quasiparticle excitations near the triple nodal points represent three-component bosons beyond that of magnonic Dirac, Weyl, and nodal-line cases. They can be regarded as a direct reflection of the intrinsic spin carried by magnons. Furthermore, we show that the magnonic triple nodal points can split into magnonic Weyl points, as the system transits from a non-collinear spin structure to a non-coplanar one with a non-zero scalar spin chirality. Our results not only apply to insulating antiferromagnets, but also provide a platform to seek for triple nodal points in metallic antiferromagnets.

  4. Unconventional Quantum Critical Points

    OpenAIRE

    Xu, Cenke

    2012-01-01

    In this paper we review the theory of unconventional quantum critical points that are beyond the Landau's paradigm. Three types of unconventional quantum critical points will be discussed: (1). The transition between topological order and semiclassical spin ordered phase; (2). The transition between topological order and valence bond solid phase; (3). The direct second order transition between different competing orders. We focus on the field theory and universality class of these unconventio...

  5. Critical point predication device

    International Nuclear Information System (INIS)

    Matsumura, Kazuhiko; Kariyama, Koji.

    1996-01-01

    An operation for predicting a critical point by using a existent reverse multiplication method has been complicated, and an effective multiplication factor could not be plotted directly to degrade the accuracy for the prediction. The present invention comprises a detector counting memory section for memorizing the counting sent from a power detector which monitors the reactor power, a reverse multiplication factor calculation section for calculating the reverse multiplication factor based on initial countings and current countings of the power detector, and a critical point prediction section for predicting the criticality by the reverse multiplication method relative to effective multiplication factors corresponding to the state of the reactor core previously determined depending on the cases. In addition, a reactor core characteristic calculation section is added for analyzing an effective multiplication factor depending on the state of the reactor core. Then, if the margin up to the criticality is reduced to lower than a predetermined value during critical operation, an alarm is generated to stop the critical operation when generation of a period of more than a predetermined value predicted by succeeding critical operation. With such procedures, forecasting for the critical point can be easily predicted upon critical operation to greatly mitigate an operator's burden and improve handling for the operation. (N.H.)

  6. Relative Critical Points

    Directory of Open Access Journals (Sweden)

    Debra Lewis

    2013-05-01

    Full Text Available Relative equilibria of Lagrangian and Hamiltonian systems with symmetry are critical points of appropriate scalar functions parametrized by the Lie algebra (or its dual of the symmetry group. Setting aside the structures – symplectic, Poisson, or variational – generating dynamical systems from such functions highlights the common features of their construction and analysis, and supports the construction of analogous functions in non-Hamiltonian settings. If the symmetry group is nonabelian, the functions are invariant only with respect to the isotropy subgroup of the given parameter value. Replacing the parametrized family of functions with a single function on the product manifold and extending the action using the (coadjoint action on the algebra or its dual yields a fully invariant function. An invariant map can be used to reverse the usual perspective: rather than selecting a parametrized family of functions and finding their critical points, conditions under which functions will be critical on specific orbits, typically distinguished by isotropy class, can be derived. This strategy is illustrated using several well-known mechanical systems – the Lagrange top, the double spherical pendulum, the free rigid body, and the Riemann ellipsoids – and generalizations of these systems.

  7. Critical Points of Contact

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Morelli, Nicola

    2011-01-01

    In contemporary urban societies multiple networks and systems interact, overlap, exist in parallel, converge, conflict etc. creating unforeseen complexity and less transparency. By exploring how layered networks of physical movement, service information, goods delivery, commercial communication etc....... are connected (and disconnected) we get a much better understanding of how to design and intervene regardless if we are thinking about public spaces in the city or new systems of service design. The many networks orchestrating and facilitating contemporary everyday life are dependent on the strategic sites...... where the networks meet and establish contact. Thus we argue for the usefulness of the notion of Critical Point of Contact (CPC) to deepen our understanding of the actual life within networks. En route to this notion we draw upon theories within as diverse realms such as interaction design, service...

  8. Critical Points of Contact

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Wind, Simon; Lanng, Ditte Bendix

    2012-01-01

    student studios made at the 1st semester of the Urban Design Master Programme in the fall of 2009 and 2010. The CPC concept is double edged since it both provides the stepping-stone for analysis as well as scaffolding for intervention and re-design. Thereby, it fits the underlying philosophy of teaching......In this brief article, we shall illustrate the application of the analytical and interventionist concept of ‘Critical Points of Contact’ (CPC) through a number of urban design studios. The notion of CPC has been developed over a span of the last three to four years and is reported in more detail...... elsewhere (Jensen & Morelli 2011). In this article, we will only discuss the conceptual and theoretical framing superficially, since our real interest is to show and discuss the concept's application value to spatial design in a number of urban design studios. The 'data' or the projects presented are seven...

  9. X (5) critical-point structure in a finite system

    International Nuclear Information System (INIS)

    Leviatan, A.

    2005-01-01

    X (5) is a paradigm for the structure at the critical point of a particular first-order phase transition for which the intrinsic energy surface has two degenerate minima separated by a low barrier. For a finite system, we show that the dynamics at such a critical point can be described by an effective deformation determined by minimizing the energy surface after projection onto angular momentum zero and combined with two-level mixing. Wave functions of a particular analytic form are used to derive estimates for energies and quadrupole rates at the critical point

  10. Why Bond Critical Points Are Not "Bond" Critical Points.

    Science.gov (United States)

    Shahbazian, Shant

    2017-12-28

    Equating (3,-1) critical points (CPs), derived from the topological analysis of the electron densities, to chemical bonds has triggered a lot of confusion in recent years. Part of this confusion stems from calling these CPs "bond" CPs (BCPs). While the origin of this terminology is traceable to the late seventies and beginning of eighties, when it sounded reasonable, new computational studies conducted on molecular electron densities cast serious doubt on the supposed universal equivalence between the chemical bonds and (3,-1) CPs. Herein, recent computational studies are briefly reviewed to demonstrate why (3,-1) CPs are not indicators of chemical bonds. It is discussed why this confusing terminology needs to be changed and reemphasized that (3,-1) CPs should be called "line" critical points (LCPs). The proposed terminology detaches the topological properties of molecular electron densities from any a priori chemical interpretation. Such detachment, if adopted by other authors, will hopefully prevent further misinterpretation of the data emerging from the quantum theory of atoms in molecules (QTAIM). © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Interval Mathematics Applied to Critical Point Transitions

    Directory of Open Access Journals (Sweden)

    Benito A. Stradi

    2012-03-01

    Full Text Available The determination of critical points of mixtures is important for both practical and theoretical reasons in the modeling of phase behavior, especially at high pressure. The equations that describe the behavior of complex mixtures near critical points are highly nonlinear and with multiplicity of solutions to the critical point equations. Interval arithmetic can be used to reliably locate all the critical points of a given mixture. The method also verifies the nonexistence of a critical point if a mixture of a given composition does not have one. This study uses an interval Newton/Generalized Bisection algorithm that provides a mathematical and computational guarantee that all mixture critical points are located. The technique is illustrated using several example problems. These problems involve cubic equation of state models; however, the technique is general purpose and can be applied in connection with other nonlinear problems.

  12. Critical point anomalies include expansion shock waves

    NARCIS (Netherlands)

    Nannen, N.R.; Guardone, A.; Colonna, P.

    2014-01-01

    From first-principle fluid dynamics, complemented by a rigorous state equation accounting for critical anomalies, we discovered that expansion shock waves may occur in the vicinity of the liquid-vapor critical point in the two-phase region. Due to universality of near-critical thermodynamics, the

  13. Critical-Point Structure in Finite Nuclei

    International Nuclear Information System (INIS)

    Leviatan, A.

    2006-01-01

    Properties of quantum shape-phase transitions in finite nuclei are considered in the framework of the interacting boson model. Special emphasis is paid to the dynamics at the critical-point of a general first-order phase transition

  14. Fermion-induced quantum critical points.

    Science.gov (United States)

    Li, Zi-Xiang; Jiang, Yi-Fan; Jian, Shao-Kai; Yao, Hong

    2017-08-22

    A unified theory of quantum critical points beyond the conventional Landau-Ginzburg-Wilson paradigm remains unknown. According to Landau cubic criterion, phase transitions should be first-order when cubic terms of order parameters are allowed by symmetry in the Landau-Ginzburg free energy. Here, from renormalization group analysis, we show that second-order quantum phase transitions can occur at such putatively first-order transitions in interacting two-dimensional Dirac semimetals. As such type of Landau-forbidden quantum critical points are induced by gapless fermions, we call them fermion-induced quantum critical points. We further introduce a microscopic model of SU(N) fermions on the honeycomb lattice featuring a transition between Dirac semimetals and Kekule valence bond solids. Remarkably, our large-scale sign-problem-free Majorana quantum Monte Carlo simulations show convincing evidences of a fermion-induced quantum critical points for N = 2, 3, 4, 5 and 6, consistent with the renormalization group analysis. We finally discuss possible experimental realizations of the fermion-induced quantum critical points in graphene and graphene-like materials.Quantum phase transitions are governed by Landau-Ginzburg theory and the exceptions are rare. Here, Li et al. propose a type of Landau-forbidden quantum critical points induced by gapless fermions in two-dimensional Dirac semimetals.

  15. Multiply Degenerate Exceptional Points and Quantum Phase Transitions

    Czech Academy of Sciences Publication Activity Database

    Borisov, D.; Růžička, František; Znojil, Miloslav

    2015-01-01

    Roč. 54, č. 12 (2015), s. 4293-4305 ISSN 0020-7748 Institutional support: RVO:61389005 Keywords : quantum mechanics * Cryptohermitian observbles * spectra and pseudospectra * real exceptional points * phase transitions Subject RIV: BE - Theoretical Physics Impact factor: 1.041, year: 2015

  16. QCD critical point: The race is on

    Indian Academy of Sciences (India)

    2015-05-06

    May 6, 2015 ... Critical points in a phase diagram in the temperature–density plane are special for several reasons. Starting from their .... Extending this approach to larger and fine lattices appears not to be easy because of an .... (filled) points display the results for the ratio (root) method (from ref. [21]). Figure 1 shows the ...

  17. Controlling superconductivity by tunable quantum critical points.

    Science.gov (United States)

    Seo, S; Park, E; Bauer, E D; Ronning, F; Kim, J N; Shim, J-H; Thompson, J D; Park, Tuson

    2015-03-04

    The heavy fermion compound CeRhIn5 is a rare example where a quantum critical point, hidden by a dome of superconductivity, has been explicitly revealed and found to have a local nature. The lack of additional examples of local types of quantum critical points associated with superconductivity, however, has made it difficult to unravel the role of quantum fluctuations in forming Cooper pairs. Here, we show the precise control of superconductivity by tunable quantum critical points in CeRhIn5. Slight tin-substitution for indium in CeRhIn5 shifts its antiferromagnetic quantum critical point from 2.3 GPa to 1.3 GPa and induces a residual impurity scattering 300 times larger than that of pure CeRhIn5, which should be sufficient to preclude superconductivity. Nevertheless, superconductivity occurs at the quantum critical point of the tin-doped metal. These results underline that fluctuations from the antiferromagnetic quantum criticality promote unconventional superconductivity in CeRhIn5.

  18. Black holes as critical point of quantum phase transition.

    Science.gov (United States)

    Dvali, Gia; Gomez, Cesar

    We reformulate the quantum black hole portrait in the language of modern condensed matter physics. We show that black holes can be understood as a graviton Bose-Einstein condensate at the critical point of a quantum phase transition, identical to what has been observed in systems of cold atoms. The Bogoliubov modes that become degenerate and nearly gapless at this point are the holographic quantum degrees of freedom responsible for the black hole entropy and the information storage. They have no (semi)classical counterparts and become inaccessible in this limit. These findings indicate a deep connection between the seemingly remote systems and suggest a new quantum foundation of holography. They also open an intriguing possibility of simulating black hole information processing in table-top labs.

  19. Black Holes as Critical Point of Quantum Phase Transition

    CERN Document Server

    Dvali, Gia

    2014-01-01

    We reformulate the quantum black hole portrait in the language of modern condensed matter physics. We show that black holes can be understood as a graviton Bose-Einstein condensate at the critical point of a quantum phase transition, identical to what has been observed in systems of cold atoms. The Bogoliubov modes that become degenerate and nearly gapless at this point are the holographic quantum degrees of freedom responsible for the black hole entropy and the information storage. They have no (semi)classical counterparts and become inaccessible in this limit. These findings indicate a deep connection between the seemingly remote systems and suggest a new quantum foundation of holography. They also open an intriguing possibility of simulating black hole information processing in table-top labs.

  20. Critical points and nonlinear variational problems

    International Nuclear Information System (INIS)

    Ambrosetti, A.

    1992-01-01

    This monograph deals with critical point theory and its applications to some classes of nonlinear variational problems. The abstract setting includes the Lusternik-Schnirelman theory and minimax methods for unbounded functionals. Applications to elliptic boundary value problems, Vortex theory, homoclinic orbits and conservative systems with singular potentials are discussed. (author). refs

  1. Critical point of view: a Wikipedia reader

    NARCIS (Netherlands)

    Lovink, G.; Tkacz, N.

    2011-01-01

    For millions of internet users around the globe, the search for new knowledge begins with Wikipedia. The encyclopedia’s rapid rise, novel organization, and freely offered content have been marveled at and denounced by a host of commentators. Critical Point of View moves beyond unflagging praise,

  2. Universal signatures of fractionalized quantum critical points.

    Science.gov (United States)

    Isakov, Sergei V; Melko, Roger G; Hastings, Matthew B

    2012-01-13

    Ground states of certain materials can support exotic excitations with a charge equal to a fraction of the fundamental electron charge. The condensation of these fractionalized particles has been predicted to drive unusual quantum phase transitions. Through numerical and theoretical analysis of a physical model of interacting lattice bosons, we establish the existence of such an exotic critical point, called XY*. We measure a highly nonclassical critical exponent η = 1.493 and construct a universal scaling function of winding number distributions that directly demonstrates the distinct topological sectors of an emergent Z(2) gauge field. The universal quantities used to establish this exotic transition can be used to detect other fractionalized quantum critical points in future model and material systems.

  3. Critical point fluctuations in supported lipid membranes.

    Science.gov (United States)

    Connell, Simon D; Heath, George; Olmsted, Peter D; Kisil, Anastasia

    2013-01-01

    In this paper, we demonstrate that it is possible to observe many aspects of critical phenomena in supported lipid bilayers using atomic force microscopy (AFM) with the aid of stable and precise temperature control. The regions of criticality were determined by accurately measuring and calculating phase diagrams for the 2 phase L(d)-L(o) region, and tracking how it moves with temperature, then increasing the sampling density around the estimated critical regions. Compositional fluctuations were observed above the critical temperature (T(c)) and characterised using a spatial correlation function. From this analysis, the phase transition was found to be most closely described by the 2D Ising model, showing it is a critical transition. Below T(c) roughening of the domain boundaries occurred due to the reduction in line tension close to the critical point. Smaller scale density fluctuations were also detected just below T(c). At T(c), we believe we have observed fluctuations on length scales greater than 10 microm. The region of critically fluctuating 10-100 nm nanodomains has been found to extend a considerable distance above T(c) to temperatures within the biological range, and seem to be an ideal candidate for the actual structure of lipid rafts in cell membranes. Although evidence for this idea has recently emerged, this is the first direct evidence for nanoscale domains in the critical region.

  4. Fermion-induced quantum critical points

    OpenAIRE

    Li, Zi-Xiang; Jiang, Yi-Fan; Jian, Shao-Kai; Yao, Hong

    2017-01-01

    A unified theory of quantum critical points beyond the conventional Landau?Ginzburg?Wilson paradigm remains unknown. According to Landau cubic criterion, phase transitions should be first-order when cubic terms of order parameters are allowed by symmetry in the Landau?Ginzburg free energy. Here, from renormalization group analysis, we show that second-order quantum phase transitions can occur at such putatively first-order transitions in interacting two-dimensional Dirac semimetals. As such t...

  5. Miscibility Critical Points in Plasma Membranes

    Science.gov (United States)

    Machta, Benjamin; Veatch, Sarah; Papanikolaou, Stefanos; Sethna, James P.

    2009-03-01

    Lipid bilayers surround all cells and are home to a host of proteins and lipids that mediate interactions between the cell and its environment. Recent experimental work has shown that simple membranes composed of three lipid components show complex phase behavior at temperatures in the physiological range. For example, two liquid phases and a gel or solid phase are seen, and a second order phase transition with Ising critical behavior can be reached at a boundary of the liquid-liquid coexistence region [1]. Surprisingly, membrane vesicles isolated from living cells can be tuned with a single parameter (temperature) to criticality [1]. This suggests that cell membranes in vivo sit near miscibility critical points, and may help explain some of the paradoxes associated with putative lipid rafts proposed in other experiments. Here we report on work mapping phase diagrams for the simple membranes utilizing NMR and microscopy data. In addition, we use canonical models of phase transitions to understand the qualitative features of the membranes. Finally we explore ideas from information theory and self organized criticality to understand how and why real cells maintain a membrane near criticality. [1] Honerkamp-Smith, Veatch, and Keller, Biochim Biophys Acta. 2008 (in press)

  6. Dynamical Response near Quantum Critical Points.

    Science.gov (United States)

    Lucas, Andrew; Gazit, Snir; Podolsky, Daniel; Witczak-Krempa, William

    2017-02-03

    We study high-frequency response functions, notably the optical conductivity, in the vicinity of quantum critical points (QCPs) by allowing for both detuning from the critical coupling and finite temperature. We consider general dimensions and dynamical exponents. This leads to a unified understanding of sum rules. In systems with emergent Lorentz invariance, powerful methods from quantum field theory allow us to fix the high-frequency response in terms of universal coefficients. We test our predictions analytically in the large-N O(N) model and using the gauge-gravity duality and numerically via quantum Monte Carlo simulations on a lattice model hosting the interacting superfluid-insulator QCP. In superfluid phases, interacting Goldstone bosons qualitatively change the high-frequency optical conductivity and the corresponding sum rule.

  7. Detecting quantum critical points using bipartite fluctuations.

    Science.gov (United States)

    Rachel, Stephan; Laflorencie, Nicolas; Song, H Francis; Le Hur, Karyn

    2012-03-16

    We show that the concept of bipartite fluctuations F provides a very efficient tool to detect quantum phase transitions in strongly correlated systems. Using state-of-the-art numerical techniques complemented with analytical arguments, we investigate paradigmatic examples for both quantum spins and bosons. As compared to the von Neumann entanglement entropy, we observe that F allows us to find quantum critical points with much better accuracy in one dimension. We further demonstrate that F can be successfully applied to the detection of quantum criticality in higher dimensions with no prior knowledge of the universality class of the transition. Promising approaches to experimentally access fluctuations are discussed for quantum antiferromagnets and cold gases.

  8. Higgs inflation at the critical point

    CERN Document Server

    Bezrukov, Fedor

    2014-01-01

    Higgs inflation can occur if the Standard Model (SM) is a self-consistent effective field theory up to inflationary scale. This leads to a lower bound on the Higgs boson mass, $M_h \\geq M_{\\text{crit}}$. If $M_h$ is more than a few hundreds of MeV above the critical value, the Higgs inflation predicts the universal values of inflationary indexes, $r\\simeq 0.003$ and $n_s\\simeq 0.97$, independently on the Standard Model parameters. We show that in the vicinity of the critical point $M_{\\text{crit}}$ the inflationary indexes acquire an essential dependence on the mass of the top quark $m_t$ and $M_h$. In particular, the amplitude of the gravitational waves can exceed considerably the universal value.

  9. Big Bang as a Critical Point

    Directory of Open Access Journals (Sweden)

    Jakub Mielczarek

    2017-01-01

    Full Text Available This article addresses the issue of possible gravitational phase transitions in the early universe. We suggest that a second-order phase transition observed in the Causal Dynamical Triangulations approach to quantum gravity may have a cosmological relevance. The phase transition interpolates between a nongeometric crumpled phase of gravity and an extended phase with classical properties. Transition of this kind has been postulated earlier in the context of geometrogenesis in the Quantum Graphity approach to quantum gravity. We show that critical behavior may also be associated with a signature change in Loop Quantum Cosmology, which occurs as a result of quantum deformation of the hypersurface deformation algebra. In the considered cases, classical space-time originates at the critical point associated with a second-order phase transition. Relation between the gravitational phase transitions and the corresponding change of symmetry is underlined.

  10. Viscoelasticity of Xenon near the Critical Point

    Science.gov (United States)

    Berg, Robert F.; Moldover, Michael R.; Zimmerli, Gregory A.

    1999-01-01

    Using a novel, overdamped, oscillator flown aboard the Space Shuttle, we measured the viscosity of xenon near the liquid-vapor critical point in the frequency range 2 Hz less than or equal to f less than or equal to 12 Hz. The measured viscosity divergence is characterized by the exponent z(sub eta) = 0.0690 +/- 0.0006, in agreement with the value z(sub eta) = 0.067 +/- 0.002 calculated from a two-loop perturbation expansion. Viscoelastic behavior was evident when t = (T - T(sub c))/T(sub c) less than 10(exp -5) and dominant when t less than 10(exp -6), further from T(sub c) than predicted. Viscoelastic behavior scales as Af(tau) where tau is the fluctuation decay time. The measured value of A is 2.0 +/- 0.3 times the result of a one-loop calculation. (Uncertainties stated are one standard uncertainty.)

  11. Dimensional reduction at a quantum critical point

    Science.gov (United States)

    Sebastian, S. E.; Harrison, N.; Batista, C. D.; Balicas, L.; Jaime, M.; Sharma, P. A.; Kawashima, N.; Fisher, I. R.

    2006-06-01

    Competition between electronic ground states near a quantum critical point (QCP)-the location of a zero-temperature phase transition driven solely by quantum-mechanical fluctuations-is expected to lead to unconventional behaviour in low-dimensional systems. New electronic phases of matter have been predicted to occur in the vicinity of a QCP by two-dimensional theories, and explanations based on these ideas have been proposed for significant unsolved problems in condensed-matter physics, such as non-Fermi-liquid behaviour and high-temperature superconductivity. But the real materials to which these ideas have been applied are usually rendered three-dimensional by a finite electronic coupling between their component layers; a two-dimensional QCP has not been experimentally observed in any bulk three-dimensional system, and mechanisms for dimensional reduction have remained the subject of theoretical conjecture. Here we show evidence that the Bose-Einstein condensate of spin triplets in the three-dimensional Mott insulator BaCuSi2O6 (refs 12-16) provides an experimentally verifiable example of dimensional reduction at a QCP. The interplay of correlations on a geometrically frustrated lattice causes the individual two-dimensional layers of spin-½ Cu2+ pairs (spin dimers) to become decoupled at the QCP, giving rise to a two-dimensional QCP characterized by linear power law scaling distinctly different from that of its three-dimensional counterpart. Thus the very notion of dimensionality can be said to acquire an `emergent' nature: although the individual particles move on a three-dimensional lattice, their collective behaviour occurs in lower-dimensional space.

  12. Percolation systems away from the critical point

    Indian Academy of Sciences (India)

    ping in dead-end branches leads to asymptotic drift velocity becoming zero for strong bias, and very slow relaxation of velocity near the critical bias field. Keywords. Percolation; lattice animals ... these systems. It turns out that percolation systems, such as the classical models of disordered media show many interest-. 419 ...

  13. [Pregnancy and bariatric surgery: Critical points].

    Science.gov (United States)

    Ciangura, C; Nizard, J; Poitou-Bernert, C; Dommergues, M; Oppert, J M; Basdevant, A

    2015-06-01

    More than 200,000 people underwent obesity surgery in France. Most of them are women. Pregnancy after bariatric surgery is becoming a common situation. This surgery results in major nutritional and gastro-intestinal tract modifications that may influence or be influenced by pregnancy, and yields benefits as well as complications. A multidisciplinary management including a nutritionist, an obstetrician, an anesthesiologist, and a bariatric surgeon is required. The aim of this review is to analyze the impact of bariatric surgery on pregnancy and vice versa, and to identify the key points of this management. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  14. Electron-density critical points analysis and catastrophe theory to forecast structure instability in periodic solids.

    Science.gov (United States)

    Merli, Marcello; Pavese, Alessandro

    2018-03-01

    The critical points analysis of electron density, i.e. ρ(x), from ab initio calculations is used in combination with the catastrophe theory to show a correlation between ρ(x) topology and the appearance of instability that may lead to transformations of crystal structures, as a function of pressure/temperature. In particular, this study focuses on the evolution of coalescing non-degenerate critical points, i.e. such that ∇ρ(x c ) = 0 and λ 1 , λ 2 , λ 3 ≠ 0 [λ being the eigenvalues of the Hessian of ρ(x) at x c ], towards degenerate critical points, i.e. ∇ρ(x c ) = 0 and at least one λ equal to zero. The catastrophe theory formalism provides a mathematical tool to model ρ(x) in the neighbourhood of x c and allows one to rationalize the occurrence of instability in terms of electron-density topology and Gibbs energy. The phase/state transitions that TiO 2 (rutile structure), MgO (periclase structure) and Al 2 O 3 (corundum structure) undergo because of pressure and/or temperature are here discussed. An agreement of 3-5% is observed between the theoretical model and experimental pressure/temperature of transformation.

  15. Triply degenerate nodal points and topological phase transitions in NaCu3Te2

    Science.gov (United States)

    Xia, Yunyouyou; Li, Gang

    2017-12-01

    Quasiparticle excitations of free electrons in condensed-matter physics, characterized by the dimensionality of the band crossing, can find their elementary-particle analogs in high-energy physics, such as Majorana, Weyl, and Dirac fermions, while crystalline symmetry allows more quasiparticle excitations and exotic fermions to emerge. Using symmetry analysis and ab initio calculations, we propose that the three-dimensional honeycomb crystal NaCu3Te2 hosts triply degenerate nodal points (TDNPs) residing at the Fermi level. Furthermore, in this system we find a tunable phase transition between a trivial insulator, a TDNP phase, and a weak topological insulator (TI), triggered by a symmetry-allowed perturbation and the spin-orbital coupling (SOC). Such a topological nontrivial ternary compound not only serves as a perfect candidate for studying three-component fermions, but also provides an excellent playground for understanding the topological phase transitions between TDNPs, TIs, and trivial insulators, which distinguishes this system from other TDNP candidates.

  16. Prediction of Ideal Topological Semimetals with Triply Degenerate Points in the NaCu3 Te2 Family

    Science.gov (United States)

    Wang, Jianfeng; Sui, Xuelei; Shi, Wujun; Pan, Jinbo; Zhang, Shengbai; Liu, Feng; Wei, Su-Huai; Yan, Qimin; Huang, Bing

    2017-12-01

    Triply degenerate points (TDPs) in band structure of a crystal can generate novel TDP fermions without high-energy counterparts. Although identifying ideal TDP semimetals, which host clean TDP fermions around the Fermi level (EF) without coexisting with other quasiparticles, is critical to explore the intrinsic properties of this new fermion, it is still a big challenge and has not been achieved up to now. Here, we disclose an effective approach to search for ideal TDP semimetals via selective band crossing between antibonding s and bonding p orbitals along a line in the momentum space with C3 v symmetry. Applying this approach, we have successfully identified the NaCu3 Te2 family of compounds to be ideal TDP semimetals, where two, and only two, pairs of TDPs are located around the EF. Moreover, we demonstrate a fundamental mechanism to modulate energy splitting between a pair of TDPs, and we illustrate the intrinsic features of TDP Fermi arcs in these ideal TDP semimetals.

  17. Development of Hazard Analysis Critical Control Points (HACCP ...

    African Journals Online (AJOL)

    Development of Hazard Analysis Critical Control Points (HACCP) and Enhancement of Microbial Safety Quality during Production of Fermented Legume Based ... Nigerian Food Journal ... Critical control points during production of iru and okpehe, two fermented condiments, were identified in four processors in Nigeria.

  18. Universal Postquench Prethermalization at a Quantum Critical Point

    Science.gov (United States)

    Gagel, Pia; Orth, Peter P.; Schmalian, Jörg

    2014-11-01

    We consider an open system near a quantum critical point that is suddenly moved towards the critical point. The bath-dominated diffusive nonequilibrium dynamics after the quench is shown to follow scaling behavior, governed by a critical exponent that emerges in addition to the known equilibrium critical exponents. We determine this exponent and show that it describes universal prethermalized coarsening dynamics of the order parameter in an intermediate time regime. Implications of this quantum critical prethermalization are: (i) a power law rise of order and correlations after an initial collapse of the equilibrium state and (ii) a crossover to thermalization that occurs arbitrarily late for sufficiently shallow quenches.

  19. Critical points for electron–Mg atom elastic scattering

    Science.gov (United States)

    Kumar, Ashok; Kumar, Sunil; Rastogi, Nikhil; Raj, Deo

    2018-02-01

    The partial wave method, along with a central potential which includes the effects of static field, exchange, polarization, absorption and spin–orbit interaction, is employed to search the critical points for the elastic scattering of electrons from Mg atoms. A novel iterative procedure is developed to calculate the critical points. A pilot application is made for Mg atoms. The present investigation shows the existence of two critical point pairs (E c1 = 15.4484 eV, θ c1 = 56.930°) and (E c2 = 75.6175 eV, θ c2 = 104.261°) for the Mg atom. At critical energy E c2 and scattering angles 104.175° and 104.325°, 99% spin polarization of scattered electrons is obtained. To the best of our knowledge, no theoretical or experimental determination of critical points for the Mg (Z = 12) atom have yet been published.

  20. Multi-critical points in weakly anisotropic magnetic systems

    International Nuclear Information System (INIS)

    Basten, J.A.J.

    1979-02-01

    This report starts with a rather extensive presentation of the concepts and ideas which constitute the basis of the modern theory of static critical phenomena. It is shown how at a critical point the semi-phenomenological concepts of universality and scaling are directly related to the divergence of the correlation length and how they are extended to a calculational method for critical behaviour in Wilson's Renormalization-Group (RG) approach. Subsequently the predictions of the molecular-field and RG-theories on the phase transitions and critical behaviour in weakly anisotropic antiferromagnets are treated. In a magnetic field applied along the easy axis, these materials can display an (H,T) phase diagram which contains either a bicritical point or a tetracritical point. Especially the behaviour close to these multi-critical points, as predicted by the extended-scaling theory, is discussed. (Auth.)

  1. Critical-point symmetry in a finite system

    International Nuclear Information System (INIS)

    Leviatan, A.; Ginocchio, J. N.

    2003-01-01

    At a critical point of a second-order phase transition the intrinsic energy surface is flat and there is no stable minimum value of the deformation. However, for a finite system, we show that there is an effective deformation which can describe the dynamics at the critical point. This effective deformation is determined by minimizing the energy surface after projection onto the appropriate symmetries. We derive analytic expressions for energies and quadrupole rates which provide good estimates for these observables at the critical point

  2. Critical-point symmetry in a finite system.

    Science.gov (United States)

    Leviatan, A; Ginocchio, J N

    2003-05-30

    At a critical point of a second-order phase transition the intrinsic energy surface is flat and there is no stable minimum value of the deformation. However, for a finite system, we show that there is an effective deformation which can describe the dynamics at the critical point. This effective deformation is determined by minimizing the energy surface after projection onto the appropriate symmetries. We derive analytic expressions for energies and quadrupole rates which provide good estimates for these observables at the critical point.

  3. Interplay of quantum and classical fluctuations near quantum critical points

    International Nuclear Information System (INIS)

    Continentino, Mucio Amado

    2011-01-01

    For a system near a quantum critical point (QCP), above its lower critical dimension d L , there is in general a critical line of second-order phase transitions that separates the broken symmetry phase at finite temperatures from the disordered phase. The phase transitions along this line are governed by thermal critical exponents that are different from those associated with the quantum critical point. We point out that, if the effective dimension of the QCP, d eff = d + z (d is the Euclidean dimension of the system and z the dynamic quantum critical exponent) is above its upper critical dimension d c there is an intermingle of classical (thermal) and quantum critical fluctuations near the QCP. This is due to the breakdown of the generalized scaling relation ψ = νz between the shift exponent ψ of the critical line and the crossover exponent νz, for d + z > d c by a dangerous irrelevant interaction. This phenomenon has clear experimental consequences, like the suppression of the amplitude of classical critical fluctuations near the line of finite temperature phase transitions as the critical temperature is reduced approaching the QCP. (author)

  4. Empirical realization of a critical point description in atomic nuclei.

    Science.gov (United States)

    Casten, R F; Zamfir, N V

    2001-07-30

    It is shown that (152)Sm and other N = 90 isotones are the first empirical manifestation of the newly predicted analytic description of nuclei at the critical point of a vibrator to axial rotor phase transition.

  5. Critical Point Dryer: Tousimis 916B Series C

    Data.gov (United States)

    Federal Laboratory Consortium — Description:CORAL Name: Critical Point DryerThis system utilizes CO 2to dry fragile suspended and floating structures Specifications / Capabilities:Wafer size up to...

  6. Cubic Polynomials with Rational Roots and Critical Points

    Science.gov (United States)

    Gupta, Shiv K.; Szymanski, Waclaw

    2010-01-01

    If you want your students to graph a cubic polynomial, it is best to give them one with rational roots and critical points. In this paper, we describe completely all such cubics and explain how to generate them.

  7. Critical points of a perturbed Otha-Kawasaki functional

    OpenAIRE

    Rizzi, Matteo

    2016-01-01

    In the paper, we consider a small perturbation of the Otha-Kawasaki functional and we construct at least four critical points close to suitable translations of the Schwarz P surface with fixed volume.

  8. Partial dynamical symmetry at critical points of quantum phase transitions.

    Science.gov (United States)

    Leviatan, A

    2007-06-15

    We show that partial dynamical symmetries can occur at critical points of quantum phase transitions, in which case underlying competing symmetries are conserved exactly by a subset of states, and mix strongly in other states. Several types of partial dynamical symmetries are demonstrated with the example of critical-point Hamiltonians for first- and second-order transitions in the framework of the interacting boson model, whose dynamical symmetries correspond to different shape phases in nuclei.

  9. Partial Dynamical Symmetry at Critical Points of Quantum Phase Transitions

    International Nuclear Information System (INIS)

    Leviatan, A.

    2007-01-01

    We show that partial dynamical symmetries can occur at critical points of quantum phase transitions, in which case underlying competing symmetries are conserved exactly by a subset of states, and mix strongly in other states. Several types of partial dynamical symmetries are demonstrated with the example of critical-point Hamiltonians for first- and second-order transitions in the framework of the interacting boson model, whose dynamical symmetries correspond to different shape phases in nuclei

  10. Bulk and boundary critical behavior at Lifshitz points

    Indian Academy of Sciences (India)

    These advances opened the way towards systematic studies of boundary critical behavior at -axial Lifshitz points. The possible boundary critical behavior depends on whether the surface plane is perpendicular to one of the modulation axes or parallel to all of them. We show that the semi-infinite field theories ...

  11. Program computes single-point failures in critical system designs

    Science.gov (United States)

    Brown, W. R.

    1967-01-01

    Computer program analyzes the designs of critical systems that will either prove the design is free of single-point failures or detect each member of the population of single-point failures inherent in a system design. This program should find application in the checkout of redundant circuits and digital systems.

  12. Identification of critical points of thermal environment in broiler production

    Directory of Open Access Journals (Sweden)

    AG Menezes

    2010-03-01

    Full Text Available This paper describes an exploratory study carried out to determine critical control points and possible risks in hatcheries and broiler farms. The study was based in the identification of the potential hazards existing in broiler production, from the hatchery to the broiler farm, identifying critical control points and defining critical limits. The following rooms were analyzed in the hatchery: egg cold storage, pre-heating, incubator, and hatcher rooms. Two broiler houses were studied in two different farms. The following data were collected in the hatchery and broiler houses: temperature (ºC and relative humidity (%, air velocity (m s-1, ammonia levels, and light intensity (lx. In the broiler house study, a questionnaire using information of the Broiler Production Good Practices (BPGP manual was applied, and workers were interviewed. Risk analysis matrices were build to determine Critical Control Points (CCP. After data collection, Statistical Process Control (SPC was applied through the analysis of the Process Capacity Index, using the software program Minitab15®. Environmental temperature and relative humidity were the critical points identified in the hatchery and in both farms. The classes determined as critical control points in the broiler houses were poultry litter, feeding, drinking water, workers' hygiene and health, management and biosecurity, norms and legislation, facilities, and activity planning. It was concluded that CCP analysis, associated with SPC control tools and guidelines of good production practices, may contribute to improve quality control in poultry production.

  13. Exact renormalization group equation for the Lifshitz critical point

    Science.gov (United States)

    Bervillier, C.

    2004-10-01

    An exact renormalization equation (ERGE) accounting for an anisotropic scaling is derived. The critical and tricritical Lifshitz points are then studied at leading order of the derivative expansion which is shown to involve two differential equations. The resulting estimates of the Lifshitz critical exponents compare well with the O(ε) calculations. In the case of the Lifshitz tricritical point, it is shown that a marginally relevant coupling defies the perturbative approach since it actually makes the fixed point referred to in the previous perturbative calculations O(ε) finally unstable.

  14. Universal post-quench prethermalization at a quantum critical point

    Science.gov (United States)

    Orth, Peter P.; Gagel, Pia; Schmalian, Joerg

    2015-03-01

    We consider an open system near a quantum critical point that is suddenly moved towards the critical point. The bath-dominated diffusive non-equilibrium dynamics after the quench is shown to follow scaling behavior, governed by a critical exponent that emerges in addition to the known equilibrium critical exponents. We determine this exponent and show that it describes universal prethermalized coarsening dynamics of the order parameter in an intermediate time regime. Implications of this quantum critical prethermalization are a powerlaw rise of order and correlations after an initial collapse of the equilibrium state and a crossover to thermalization that occurs arbitrarily late for sufficiently shallow quenches. [1] P. Gagel, P. P. Orth, J. Schmalian, Phys.Rev. Lett. (in press) arXiv:1406.6387

  15. A critical analysis of the tender points in fibromyalgia.

    Science.gov (United States)

    Harden, R Norman; Revivo, Gadi; Song, Sharon; Nampiaparampil, Devi; Golden, Gary; Kirincic, Marie; Houle, Timothy T

    2007-03-01

    To pilot methodologies designed to critically assess the American College of Rheumatology's (ACR) diagnostic criteria for fibromyalgia. Prospective, psychophysical testing. An urban teaching hospital. Twenty-five patients with fibromyalgia and 31 healthy controls (convenience sample). Pressure pain threshold was determined at the 18 ACR tender points and five sham points using an algometer (dolorimeter). The patients "algometric total scores" (sums of the patients' average pain thresholds at the 18 tender points) were derived, as well as pain thresholds across sham points. The "algometric total score" could differentiate patients with fibromyalgia from normals with an accuracy of 85.7% (P pain across sham points than across ACR tender points, sham points also could be used for diagnosis (85.7%; Ps tested vs other painful conditions. The points specified by the ACR were only modestly superior to sham points in making the diagnosis. Most importantly, this pilot suggests single points, smaller groups of points, or sham points may be as effective in diagnosing fibromyalgia as the use of all 18 points, and suggests methodologies to definitively test that hypothesis.

  16. Critical Care Glucose Point-of-Care Testing.

    Science.gov (United States)

    Narla, S N; Jones, M; Hermayer, K L; Zhu, Y

    Maintaining blood glucose concentration within an acceptable range is a goal for patients with diabetes mellitus. Point-of-care glucose meters initially designed for home self-monitoring in patients with diabetes have been widely used in the hospital settings because of ease of use and quick reporting of blood glucose information. They are not only utilized for the general inpatient population but also for critically ill patients. Many factors affect the accuracy of point-of-care glucose testing, particularly in critical care settings. Inaccurate blood glucose information can result in unsafe insulin delivery which causes poor glucose control and can be fatal. Healthcare professionals should be aware of the limitations of point-of-care glucose testing. This chapter will first introduce glucose regulation in diabetes mellitus, hyperglycemia/hypoglycemia in the intensive care unit, importance of glucose control in critical care patients, and pathophysiological variables of critically ill patients that affect the accuracy of point-of-care glucose testing. Then, we will discuss currently available point-of-care glucose meters and preanalytical, analytical, and postanalytical sources of variation and error in point-of-care glucose testing. © 2016 Elsevier Inc. All rights reserved.

  17. Probing Critical Point Energies of Transition Metal Dichalcogenides: Surprising Indirect Gap of Single Layer WSe 2

    KAUST Repository

    Zhang, Chendong

    2015-09-21

    By using a comprehensive form of scanning tunneling spectroscopy, we have revealed detailed quasi-particle electronic structures in transition metal dichalcogenides, including the quasi-particle gaps, critical point energy locations, and their origins in the Brillouin zones. We show that single layer WSe surprisingly has an indirect quasi-particle gap with the conduction band minimum located at the Q-point (instead of K), albeit the two states are nearly degenerate. We have further observed rich quasi-particle electronic structures of transition metal dichalcogenides as a function of atomic structures and spin-orbit couplings. Such a local probe for detailed electronic structures in conduction and valence bands will be ideal to investigate how electronic structures of transition metal dichalcogenides are influenced by variations of local environment.

  18. Geometric Frustration and Dimensional Reduction at a Quantum Critical Point

    Science.gov (United States)

    Batista, C. D.; Schmalian, J.; Kawashima, N.; Sengupta, P.; Sebastian, S. E.; Harrison, N.; Jaime, M.; Fisher, I. R.

    2007-06-01

    We show that the spatial dimensionality of the quantum critical point associated with Bose-Einstein condensation at T=0 is reduced when the underlying lattice comprises layers coupled by a frustrating interaction. Our theoretical predictions for the critical behavior correspond very well with recent measurements in BaCuSi2O6 [ S. E. Sebastian et al., Nature (London)NATUAS0028-0836 441, 617 (2006)].

  19. Thermal conductivity at a disordered quantum critical point

    International Nuclear Information System (INIS)

    Hartnoll, Sean A.; Ramirez, David M.; Santos, Jorge E.

    2016-01-01

    Strongly disordered and strongly interacting quantum critical points are difficult to access with conventional field theoretic methods. They are, however, both experimentally important and theoretically interesting. In particular, they are expected to realize universal incoherent transport. Such disordered quantum critical theories have recently been constructed holographically by deforming a CFT by marginally relevant disorder. In this paper we find additional disordered fixed points via relevant disordered deformations of a holographic CFT. Using recently developed methods in holographic transport, we characterize the thermal conductivity in both sets of theories in 1+1 dimensions. The thermal conductivity is found to tend to a constant at low temperatures in one class of fixed points, and to scale as T 0.3 in the other. Furthermore, in all cases the thermal conductivity exhibits discrete scale invariance, with logarithmic in temperature oscillations superimposed on the low temperature scaling behavior. At no point do we use the replica trick.

  20. Critical points in logistic growth curves and treatment comparisons

    Directory of Open Access Journals (Sweden)

    José Raimundo de Souza Passos

    2012-10-01

    Full Text Available Several biological phenomena have a behavior over time mathematically characterized by a strong increasing function in the early stages of development, then by a less pronounced growth, sometimes showing stability. The separation between these phases is very important to the researcher, since the maintenance of a less productive phase results in uneconomical activity. In this report we present methods of determining critical points in logistic functions that separate the early stages of growth from the asymptotic phase, with the aim of establishing a stopping critical point in the growth and on this basis determine differences in treatments. The logistic growth model is fitted to experimental data of imbibition of araribá seeds (Centrolobium tomentosum. To determine stopping critical points the following methods were used: i accelerating growth function, ii tangent at the inflection point, iii segmented regression; iv modified segmented regression; v non-significant difference; and vi non-significant difference by simulation. The analysis of variance of the abscissas and ordinates of the breakpoints was performed with the objective of comparing treatments and methods used to determine the critical points. The methods of segmented regression and of the tangent at the inflection point lead to early stopping points, in comparison with other methods, with proportions ordinate/asymptote lower than 0.90. The non-significant difference method by simulation had higher values of abscissas for stopping point, with an average proportion ordinate/asymptote equal to 0.986. An intermediate proportion of 0.908 was observed for the acceleration function method.

  1. Slow dynamics at critical points: the field-theoretical perspective

    International Nuclear Information System (INIS)

    Gambassi, Andrea

    2006-01-01

    The dynamics at a critical point provides a simple instance of slow collective evolution, characterised by aging phenomena and by a violation of the fluctuation-dissipation relation even for long times. By virtue of the universality in critical phenomena it is possible to provide quantitative predictions for some aspects of these behaviours by field-theoretical methods. We review some of the theoretical results that have been obtained in recent years for the relevant (universal) quantities, such as the fluctuation-dissipation ratio, associated with the non-equilibrium critical dynamics

  2. Effects of Subretinal Gene Transfer at Different Time Points in a Mouse Model of Retinal Degeneration.

    Science.gov (United States)

    Dai, Xufeng; Zhang, Hua; Han, Juanjuan; He, Ying; Zhang, Yangyang; Qi, Yan; Pang, Ji-Jing

    2016-01-01

    Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is necessary for photoreceptors to generate an important lipid component of their membranes. The absence of LPCAT1 results in early and rapid rod and cone degeneration. Retinal degeneration 11 (rd11) mice carry a mutation in the Lpcat1 gene, and are an excellent model of early-onset rapid retinal degeneration (RD). To date, no reports have documented gene therapy administration in the rd11 mouse model at different ages. In this study, the AAV8 (Y733F)-smCBA-Lpcat1 vector was subretinally injected at postnatal day (P) 10, 14, 18, or 22. Four months after injection, immunohistochemistry and analysis of retinal morphology showed that treatment at P10 rescued about 82% of the wild-type retinal thickness. However, the diffusion of the vector and the resulting rescue were limited to an area around the injection site that was only 31% of the total retinal area. Injection at P14 resulted in vector diffusion that covered approximately 84% of the retina, and we found that gene therapy was more effective against RD when exposure to light was limited before and after treatment. We observed long-term preservation of electroretinogram (ERG) responses, and preservation of retinal structure, indicating that early treatment followed by limited light exposure can improve gene therapy effectiveness for the eyes of rd11 mice. Importantly, delayed treatment still partially preserved M-cones, but not S-cones, and M-cones in the rd11 retina appeared to have a longer window of opportunity for effective preservation with gene therapy. These results provide important information regarding the effects of subretinal gene therapy in the mouse model of LPCAT1-deficiency.

  3. Effects of Subretinal Gene Transfer at Different Time Points in a Mouse Model of Retinal Degeneration.

    Directory of Open Access Journals (Sweden)

    Xufeng Dai

    Full Text Available Lysophosphatidylcholine acyltransferase 1 (LPCAT1 is necessary for photoreceptors to generate an important lipid component of their membranes. The absence of LPCAT1 results in early and rapid rod and cone degeneration. Retinal degeneration 11 (rd11 mice carry a mutation in the Lpcat1 gene, and are an excellent model of early-onset rapid retinal degeneration (RD. To date, no reports have documented gene therapy administration in the rd11 mouse model at different ages. In this study, the AAV8 (Y733F-smCBA-Lpcat1 vector was subretinally injected at postnatal day (P 10, 14, 18, or 22. Four months after injection, immunohistochemistry and analysis of retinal morphology showed that treatment at P10 rescued about 82% of the wild-type retinal thickness. However, the diffusion of the vector and the resulting rescue were limited to an area around the injection site that was only 31% of the total retinal area. Injection at P14 resulted in vector diffusion that covered approximately 84% of the retina, and we found that gene therapy was more effective against RD when exposure to light was limited before and after treatment. We observed long-term preservation of electroretinogram (ERG responses, and preservation of retinal structure, indicating that early treatment followed by limited light exposure can improve gene therapy effectiveness for the eyes of rd11 mice. Importantly, delayed treatment still partially preserved M-cones, but not S-cones, and M-cones in the rd11 retina appeared to have a longer window of opportunity for effective preservation with gene therapy. These results provide important information regarding the effects of subretinal gene therapy in the mouse model of LPCAT1-deficiency.

  4. Microbial profile and critical control points during processing of 'robo ...

    African Journals Online (AJOL)

    The results were used to evaluate the relevant critical control points especially in relation to raw materials and human contaminations, process requirements and contacting of ingredients with equipment. The observed contaminants common to all samples and irrespective of the producers were the Staphylococcus aureus ...

  5. Attractive critical point from weak antilocalization on fractals

    NARCIS (Netherlands)

    Sticlet, D.C.; Akhmerov, A.R.

    2016-01-01

    We report an attractive critical point occurring in the Anderson localization scaling flow of symplectic models on fractals. The scaling theory of Anderson localization predicts that in disordered symplectic two-dimensional systems weak-antilocalization effects lead to a metal-insulator

  6. Microbial profile and critical control points during processing of 'robo ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-05-18

    May 18, 2009 ... frying, surface fat draining, open-air cooling, and holding/packaging in polyethylene films during sales and distribution. The product was, however, classified under category III with respect to risk and the significance of monitoring and evaluation of quality using the hazard analysis critical control point.

  7. Evaluation of Critical Control Points (CCPS) in the Production of ...

    African Journals Online (AJOL)

    Hazard analysis and critical control point (HACCP) was carried out during the production of African locust bean seeds condiment (Daddawa) in a location that specialized in it's manufacturing namely Kwanar – yandaddawa (Dawakin – Tofa Local Government Area) Kano State, Nigeria. The analyses consisted of ...

  8. Hazards And Critical Control Points Of Yoghurt Produced In A ...

    African Journals Online (AJOL)

    Hazard analyses of yoghurt, produced by the Dairy Unit of a Research Institute farm in Zaria were conducted to determine hazards associated with the processing of milk supplied to the unit into the milk product, and also to determine critical control points that are necessary for effective control of the hazards. The analyses ...

  9. A magnetically induced quantum critical point in holography

    NARCIS (Netherlands)

    Gursoy, U.; Gnecchi, A.; Toldo, C.; Papadoulaki, O.

    We investigate quantum critical points in a 2+1 dimensional gauge theory at finite chemical potential χ and magnetic field B. The gravity dual is based on 4D NN = 2 Fayet-Iliopoulos gauged supergravity and the solutions we consider — that are constructed analytically — are extremal, dyonic,

  10. The critical point of quantum chromodynamics through lattice and ...

    Indian Academy of Sciences (India)

    Abstract. This talk discusses methods of extending lattice computations at finite temperature into regions of finite chemical potential, and the conditions under which such results from the lattice may be compared to experiments. Such comparisons away from a critical point are absolutely essential for quantitative use of lattice ...

  11. Electron self-trapping at quantum and classical critical points

    NARCIS (Netherlands)

    Auslender, M.I.; Katsnelson, M.I.

    2006-01-01

    Using Feynman path integral technique estimations of the ground state energy have been found for a conduction electron interacting with order parameter fluctuations near quantum critical points. In some cases only singular perturbation theory in the coupling constant emerges for the electron ground

  12. Vector boson excitations near deconfined quantum critical points.

    Science.gov (United States)

    Huh, Yejin; Strack, Philipp; Sachdev, Subir

    2013-10-18

    We show that the Néel states of two-dimensional antiferromagnets have low energy vector boson excitations in the vicinity of deconfined quantum critical points. We compute the universal damping of these excitations arising from spin-wave emission. Detection of such a vector boson will demonstrate the existence of emergent topological gauge excitations in a quantum spin system.

  13. Spotlighting quantum critical points via quantum correlations at finite temperatures

    International Nuclear Information System (INIS)

    Werlang, T.; Ribeiro, G. A. P.; Rigolin, Gustavo

    2011-01-01

    We extend the program initiated by T. Werlang et al. [Phys. Rev. Lett. 105, 095702 (2010)] in several directions. Firstly, we investigate how useful quantum correlations, such as entanglement and quantum discord, are in the detection of critical points of quantum phase transitions when the system is at finite temperatures. For that purpose we study several thermalized spin models in the thermodynamic limit, namely, the XXZ model, the XY model, and the Ising model, all of which with an external magnetic field. We compare the ability of quantum discord, entanglement, and some thermodynamic quantities to spotlight the quantum critical points for several different temperatures. Secondly, for some models we go beyond nearest neighbors and also study the behavior of entanglement and quantum discord for second nearest neighbors around the critical point at finite temperature. Finally, we furnish a more quantitative description of how good all these quantities are in spotlighting critical points of quantum phase transitions at finite T, bridging the gap between experimental data and those theoretical descriptions solely based on the unattainable absolute zero assumption.

  14. Environmental Impact and Hazards Analysis Critical Control Point ...

    African Journals Online (AJOL)

    Tsire is a local meat delicacy (kebab) in northern Nigeria, which has become popular and widely acceptable throughout the country and even beyond. Three production sites of tsire were evaluated for the environmental impact and hazard analysis critical control point (HACCP) on the microbiological and chemical qualities ...

  15. Verifying critical control points for Phytophthora introduction into nurseries

    Science.gov (United States)

    N.K. Osterbauer; M. Lujan; G. McAninch; A. Trippe; S. Lane

    2013-01-01

    The Oregon Department of Agriculture implemented the Grower Assisted Inspection Program (GAIP) for nurseries in 2007. Participants in GAIP adopted best management practices (BMP) for five critical control points (CCP) (used containers, irrigation water, soil substrate, potting media, and incoming plants), where foliar Phytophthora can be introduced...

  16. Washing and chilling as critical control points in pork slaughter hazard analysis and critical control point (HACCP) systems.

    Science.gov (United States)

    Bolton, D J; Pearce, R A; Sheridan, J J; Blair, I S; McDowell, D A; Harrington, D

    2002-01-01

    The aim of this research was to examine the effects of preslaughter washing, pre-evisceration washing, final carcass washing and chilling on final carcass quality and to evaluate these operations as possible critical control points (CCPs) within a pork slaughter hazard analysis and critical control point (HACCP) system. This study estimated bacterial numbers (total viable counts) and the incidence of Salmonella at three surface locations (ham, belly and neck) on 60 animals/carcasses processed through a small commercial pork abattoir (80 pigs d(-1)). Significant reductions (P HACCP in pork slaughter plants. This research will provide a sound scientific basis on which to develop and implement effective HACCP in pork abattoirs.

  17. Diagnosis as the First Critical Point in the Treatment Trajectory

    DEFF Research Database (Denmark)

    Missel, Malene; Pedersen, Jesper H; Hendriksen, Carsten

    2015-01-01

    of patients with operable lung cancer in order to identify their needs for care interventions from the point of diagnosis to hospitalization. METHODS: We investigated patients' lived experiences from a longitudinal perspective at 4 critical time points during the treatment trajectory; we present here...... the patient to face a new life situation, and demands one-on-one supportive care. CONCLUSIONS: Diagnosis is the first critical point for patients with operable lung cancer and disrupts their daily life. Patients need psychosocial support during the period from diagnosis to surgical intervention and patient......-tailored one-on-one information. IMPLICATIONS FOR PRACTICE: This article contributes to the knowledge base of support needs of lung cancer patients. Interventions aimed at supportive care during the period between diagnosis and surgical intervention should be researched....

  18. Highly macroscopically degenerated single-point ground states as source of specific heat capacity anomalies in magnetic frustrated systems

    Science.gov (United States)

    Jurčišinová, E.; Jurčišin, M.

    2018-04-01

    Anomalies of the specific heat capacity are investigated in the framework of the exactly solvable antiferromagnetic spin- 1 / 2 Ising model in the external magnetic field on the geometrically frustrated tetrahedron recursive lattice. It is shown that the Schottky-type anomaly in the behavior of the specific heat capacity is related to the existence of unique highly macroscopically degenerated single-point ground states which are formed on the borders between neighboring plateau-like ground states. It is also shown that the very existence of these single-point ground states with large residual entropies predicts the appearance of another anomaly in the behavior of the specific heat capacity for low temperatures, namely, the field-induced double-peak structure, which exists, and should be observed experimentally, along with the Schottky-type anomaly in various frustrated magnetic system.

  19. Detection of quantum critical points by a probe qubit.

    Science.gov (United States)

    Zhang, Jingfu; Peng, Xinhua; Rajendran, Nageswaran; Suter, Dieter

    2008-03-14

    Quantum phase transitions occur when the ground state of a quantum system undergoes a qualitative change when an external control parameter reaches a critical value. Here, we demonstrate a technique for studying quantum systems undergoing a phase transition by coupling the system to a probe qubit. It uses directly the increased sensibility of the quantum system to perturbations when it is close to a critical point. Using an NMR quantum simulator, we demonstrate this measurement technique for two different types of quantum phase transitions in an Ising spin chain.

  20. Delirium in Critically Ill Children: An International Point Prevalence Study.

    Science.gov (United States)

    Traube, Chani; Silver, Gabrielle; Reeder, Ron W; Doyle, Hannah; Hegel, Emily; Wolfe, Heather A; Schneller, Christopher; Chung, Melissa G; Dervan, Leslie A; DiGennaro, Jane L; Buttram, Sandra D W; Kudchadkar, Sapna R; Madden, Kate; Hartman, Mary E; deAlmeida, Mary L; Walson, Karen; Ista, Erwin; Baarslag, Manuel A; Salonia, Rosanne; Beca, John; Long, Debbie; Kawai, Yu; Cheifetz, Ira M; Gelvez, Javier; Truemper, Edward J; Smith, Rebecca L; Peters, Megan E; O'Meara, A M Iqbal; Murphy, Sarah; Bokhary, Abdulmohsen; Greenwald, Bruce M; Bell, Michael J

    2017-04-01

    To determine prevalence of delirium in critically ill children and explore associated risk factors. Multi-institutional point prevalence study. Twenty-five pediatric critical care units in the United States, the Netherlands, New Zealand, Australia, and Saudi Arabia. All children admitted to the pediatric critical care units on designated study days (n = 994). Children were screened for delirium using the Cornell Assessment of Pediatric Delirium by the bedside nurse. Demographic and treatment-related variables were collected. Primary study outcome measure was prevalence of delirium. In 159 children, a final determination of mental status could not be ascertained. Of the 835 remaining subjects, 25% screened positive for delirium, 13% were classified as comatose, and 62% were delirium-free and coma-free. Delirium prevalence rates varied significantly with reason for ICU admission, with highest delirium rates found in children admitted with an infectious or inflammatory disorder. For children who were in the PICU for 6 or more days, delirium prevalence rate was 38%. In a multivariate model, risk factors independently associated with development of delirium included age less than 2 years, mechanical ventilation, benzodiazepines, narcotics, use of physical restraints, and exposure to vasopressors and antiepileptics. Delirium is a prevalent complication of critical illness in children, with identifiable risk factors. Further multi-institutional, longitudinal studies are required to investigate effect of delirium on long-term outcomes and possible preventive and treatment measures. Universal delirium screening is practical and can be implemented in pediatric critical care units.

  1. Critical Points of the Electric Field from a Collection of Point Charges

    Energy Technology Data Exchange (ETDEWEB)

    Max, N; Weinkauf, T

    2007-02-16

    The electric field around a molecule is generated by the charge distribution of its constituents: positively charged atomic nuclei, which are well approximated by point charges, and negatively charged electrons, whose probability density distribution can be computed from quantum mechanics. For the purposes of molecular mechanics or dynamics, the charge distribution is often approximated by a collection of point charges, with either a single partial charge at each atomic nucleus position, representing both the nucleus and the electrons near it, or as several different point charges per atom. The critical points in the electric field are useful in visualizing its geometrical and topological structure, and can help in understanding the forces and motion it induces on a charged ion or neutral dipole. Most visualization tools for vector fields use only samples of the field on the vertices of a regular grid, and some sort of interpolation, for example, trilinear, on the grid cells. There is less risk of missing or misinterpreting topological features if they can be derived directly from the analytic formula for the field, rather than from its samples. This work presents a method which is guaranteed to find all the critical points of the electric field from a finite set of point charges. To visualize the field topology, we have modified the saddle connector method to use the analytic formula for the field.

  2. Ramp and periodic dynamics across non-Ising critical points

    Science.gov (United States)

    Ghosh, Roopayan; Sen, Arnab; Sengupta, K.

    2018-01-01

    We study ramp and periodic dynamics of ultracold bosons in an one-dimensional (1D) optical lattice which supports quantum critical points separating a uniform and a Z3 or Z4 symmetry broken density-wave ground state. Our protocol involves both linear and periodic drives which takes the system from the uniform state to the quantum critical point (for linear drive protocol) or to the ordered state and back (for periodic drive protocols) via controlled variation of a parameter of the system Hamiltonian. We provide exact numerical computation, for finite-size boson chains with L ≤24 using exact diagonalization (ED), of the excitation density D , the wave function overlap F , and the excess energy Q at the end of the drive protocol. For the linear ramp protocol, we identify the range of ramp speeds for which D and Q show Kibble-Zurek scaling. We find, based on numerical analysis with L ≤24 , that such scaling is consistent with that expected from critical exponents of the q -state Potts universality class with q =3 ,4 . For the periodic protocol, we show that the model displays near-perfect dynamical freezing at specific frequencies; at these frequencies D ,Q →0 and |F |→1 . We provide a semi-analytic explanation of such freezing behavior and relate this phenomenon to a many-body version of Stuckelberg interference. We suggest experiments which can test our theory.

  3. Towards a controlled study of the QCD critical point

    CERN Document Server

    De Forcrand, Philippe

    2008-01-01

    The phase diagram of QCD, as a function of temperature T and quark chemical potential mu, may contain a critical point (mu_E,T_E) whose non-perturbative nature makes it a natural object of lattice studies. However, the sign problem prevents the application of standard Monte Carlo techniques at non-zero baryon density. We have been pursuing an approach free of the sign problem, where the chemical potential is taken as imaginary and the results are Taylor-expanded in mu/T about mu=0, then analytically continued to real mu. Within this approach we have determined the sensitivity of the critical chemical potential mu_E to the quark mass, d(\\mu_E)^2/dm_q|_{\\mu_E=0}. Our study indicates that the critical point moves to {\\em smaller} chemical potential as the quark mass {\\em increases}. This finding, contrary to common wisdom, implies that the deconfinement crossover, which takes place in QCD at mu=0 when the temperature is raised, will remain a crossover in the mu-region where our Taylor expansion can be trusted. I...

  4. The Critical Point Entanglement and Chaos in the Dicke Model

    Directory of Open Access Journals (Sweden)

    Lina Bao

    2015-07-01

    Full Text Available Ground state properties and level statistics of the Dicke model for a finite number of atoms are investigated based on a progressive diagonalization scheme (PDS. Particle number statistics, the entanglement measure and the Shannon information entropy at the resonance point in cases with a finite number of atoms as functions of the coupling parameter are calculated. It is shown that the entanglement measure defined in terms of the normalized von Neumann entropy of the reduced density matrix of the atoms reaches its maximum value at the critical point of the quantum phase transition where the system is most chaotic. Noticeable change in the Shannon information entropy near or at the critical point of the quantum phase transition is also observed. In addition, the quantum phase transition may be observed not only in the ground state mean photon number and the ground state atomic inversion as shown previously, but also in fluctuations of these two quantities in the ground state, especially in the atomic inversion fluctuation.

  5. Shear Thinning Near the Critical Point of Xenon

    Science.gov (United States)

    Zimmerli, Gregory A.; Berg, Robert F.; Moldover, Michael R.; Yao, Minwu

    2008-01-01

    We measured shear thinning, a viscosity decrease ordinarily associated with complex liquids, near the critical point of xenon. The data span a wide range of reduced shear rate: 10(exp -3) xenon at amplitudes 3 mu,m 430 mu, and frequencies 1 Hz dynamic critical scaling. At high frequencies, (omega tau)(exp 2) > gamma-dot tau, C(sub gamma) depends also on both x(sub 0) and omega. The data were compared with numerical calculations based on the Carreau-Yasuda relation for complex fluids: eta(gamma-dot)/eta(0)=[1+A(sub gamma)|gamma-dot tau|](exp - chi(sub eta)/3+chi(sub eta)), where chi(sub eta) =0.069 is the critical exponent for viscosity and mode-coupling theory predicts A(sub gamma) =0.121. For xenon we find A(sub gamma) =0.137 +/- 0.029, in agreement with the mode coupling value. Remarkably, the xenon data close to the critical temperature T(sub c) were independent of the cooling rate (both above and below T(sub c) and these data were symmetric about T(sub c) to within a temperature scale factor. The scale factors for the magnitude of the oscillator s response differed from those for the oscillator's phase; this suggests that the surface tension of the two-phase domains affected the drag on the screen below T(sub c).

  6. Universal postquench coarsening and aging at a quantum critical point

    Science.gov (United States)

    Gagel, Pia; Orth, Peter P.; Schmalian, Jörg

    2015-09-01

    The nonequilibrium dynamics of a system that is located in the vicinity of a quantum critical point is affected by the critical slowing down of order-parameter correlations with the potential for novel out-of-equilibrium universality. After a quantum quench, i.e., a sudden change of a parameter in the Hamiltonian, such a system is expected to almost instantly fall out of equilibrium and undergo aging dynamics, i.e., dynamics that depends on the time passed since the quench. Investigating the quantum dynamics of an N -component φ4 model coupled to an external bath, we determine this universal aging and demonstrate that the system undergoes a coarsening, governed by a critical exponent that is unrelated to the equilibrium exponents of the system. We analyze this behavior in the large-N limit, which is complementary to our earlier renormalization-group analysis, allowing in particular the direct investigation of the order-parameter dynamics in the symmetry-broken phase and at the upper critical dimension. By connecting the long-time limit of fluctuations and response, we introduce a distribution function that shows that the system remains nonthermal and exhibits quantum coherence even on long time scales.

  7. Emergent symmetry and dimensional reduction at a quantum critical point

    Science.gov (United States)

    Schmalian, J.; Batista, C. D.

    2008-03-01

    We show that the spatial dimensionality of the quantum critical point associated with Bose-Einstein condensation at T=0 is reduced when the underlying lattice comprises a set of layers coupled by a frustrating interaction. For this purpose, we use an heuristic mean field approach that is complemented and justified by a more rigorous renormalization group analysis. Due to the presence of an emergent symmetry, i.e., a symmetry of the ground state that is absent in the underlying Hamiltonian, a three-dimensional interacting Bose system undergoes a chemical potential tuned quantum phase transition that is strictly two-dimensional. Our theoretical predictions for the critical temperature as a function of the chemical potential correspond very well with recent measurements in BaCuSi2O6 .

  8. Quantum Triple Point and Quantum Critical End Points in Metallic Magnets.

    Science.gov (United States)

    Belitz, D; Kirkpatrick, T R

    2017-12-29

    In low-temperature metallic magnets, ferromagnetic (FM) and antiferromagnetic (AFM) orders can exist, adjacent to one another or concurrently, in the phase diagram of a single system. We show that universal quantum effects qualitatively alter the known phase diagrams for classical magnets. They shrink the region of concurrent FM and AFM order, change various transitions from second to first order, and, in the presence of a magnetic field, lead to either a quantum triple point where the FM, AFM, and paramagnetic phases all coexist or a quantum critical end point.

  9. Universality away from critical points in a thermostatistical model

    Science.gov (United States)

    Lapilli, C. M.; Wexler, C.; Pfeifer, P.

    Nature uses phase transitions as powerful regulators of processes ranging from climate to the alteration of phase behavior of cell membranes to protect cells from cold, building on the fact that thermodynamic properties of a solid, liquid, or gas are sensitive fingerprints of intermolecular interactions. The only known exceptions from this sensitivity are critical points. At a critical point, two phases become indistinguishable and thermodynamic properties exhibit universal behavior: systems with widely different intermolecular interactions behave identically. Here we report a major counterexample. We show that different members of a family of two-dimensional systems —the discrete p-state clock model— with different Hamiltonians describing different microscopic interactions between molecules or spins, may exhibit identical thermodynamic behavior over a wide range of temperatures. The results generate a comprehensive map of the phase diagram of the model and, by virtue of the discrete rotors behaving like continuous rotors, an emergent symmetry, not present in the Hamiltonian. This symmetry, or many-to-one map of intermolecular interactions onto thermodynamic states, demonstrates previously unknown limits for macroscopic distinguishability of different microscopic interactions.

  10. A QCD chiral critical point at small chemical potential: is it there or not?

    CERN Document Server

    de Forcrand, Philippe; Philipsen, Owe

    2007-01-01

    For a QCD chiral critical point to exist, the parameter region of small quark masses for which the finite temperature transition is first-order must expand when the chemical potential is turned on. This can be tested by a Taylor expansion of the critical surface (m_{u,d},m_s)_c(mu). We present a new method to perform this Taylor expansion numerically, which we first test on an effective model of QCD with static, dense quarks. We then present the results for QCD with 3 degenerate flavors. For a lattice with N_t=4 time-slices, the first-order region shrinks as the chemical potential is turned on. This implies that, for physical quark masses, the analytic crossover which occurs at mu=0 between the hadronic and the plasma regimes remains crossover in the mu-region where a Taylor expansion is reliable, i.e. mu less than or similar to T. We present preliminary results from finer lattices indicating that this situation persists, as does the discrepancy between the curvature of T_c(mu) and the experimentally observed...

  11. Impurities near an antiferromagnetic-singlet quantum critical point

    International Nuclear Information System (INIS)

    Mendes-Santos, T.; Costa, N. C.; Batrouni, G.

    2017-01-01

    Heavy-fermion systems and other strongly correlated electron materials often exhibit a competition between antiferromagnetic (AF) and singlet ground states. We examine the effect of impurities in the vicinity of such an AF-singlet quantum critical point (QCP), through an appropriately defined “impurity susceptibility” χimp, using exact quantum Monte Carlo simulations. Our key finding is a connection within a single calculational framework between AF domains induced on the singlet side of the transition and the behavior of the nuclear magnetic resonance (NMR) relaxation rate 1/T1. Furthermore, we show that local NMR measurements provide a diagnostic for the location of the QCP, which agrees remarkably well with the vanishing of the AF order parameter and large values of χimp.

  12. Energy scales and magnetoresistance at a quantum critical point

    Energy Technology Data Exchange (ETDEWEB)

    Shaginyan, V.R. [Petersburg Nuclear Physics Institute, RAS, Gatchina, 188300 (Russian Federation); Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); CTSPS, Clark Atlanta University, Atlanta, GA 30314 (United States)], E-mail: vrshag@thd.pnpi.spb.ru; Amusia, M.Ya. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); Msezane, A.Z. [CTSPS, Clark Atlanta University, Atlanta, GA 30314 (United States); Popov, K.G. [Komi Science Center, Ural Division, RAS, 3a Chernova street, Syktyvkar, 167982 (Russian Federation); Stephanovich, V.A. [Opole University, Institute of Mathematics and Informatics, Opole, 45-052 (Poland)

    2009-03-02

    The magnetoresistance (MR) of CeCoIn{sub 5} is notably different from that in many conventional metals. We show that a pronounced crossover from negative to positive MR at elevated temperatures and fixed magnetic fields is determined by the scaling behavior of quasiparticle effective mass. At a quantum critical point (QCP) this dependence generates kinks (crossover points from fast to slow growth) in thermodynamic characteristics (like specific heat, magnetization, etc.) at some temperatures when a strongly correlated electron system transits from the magnetic field induced Landau-Fermi liquid (LFL) regime to the non-Fermi liquid (NFL) one taking place at rising temperatures. We show that the above kink-like peculiarity separates two distinct energy scales in QCP vicinity - low temperature LFL scale and high temperature one related to NFL regime. Our comprehensive theoretical analysis of experimental data permits to reveal for the first time new MR and kinks scaling behavior as well as to identify the physical reasons for above energy scales.

  13. Critical limits for the control points for halal poultry slaughter.

    Science.gov (United States)

    Shahdan, Intan Azura; Regenstein, Joe Mac; Rahman, Mohammad Tariqur

    2017-06-01

    This study proposes critical limits (CL) for control points for halal slaughter (CPHS). Previously, 6 control points (CP) were determined, and CL for these 6 CPHS are suggested based on: 1) a literature survey for the CL for CP 1 (poultry breeding, rearing, and poultry feed) and CP 2 (welfare of poultry during transportation and lairage); 2) a field survey of slaughter plants in Kuantan (Malaysia) for CP 3 (immobilization), CP 4 (slaughter), CP 5 (time for full bleed-out), and CP 6 (washing and packaging); and 3) controlled experiments to refine the CL for CP 3, 4, and 5. The CL for CP 1 focused on stress reduction during rearing and use of substances that could compromise poultry meat wholesomeness. The CL for CP 2 emphasizes humane best-practices for handling poultry during lairage. The CL for CP 3 suggests a gap of 5 s between 2 shackles if only one shackler is employed and shackling times of zero adulteration from haram species and substances. © 2016 Poultry Science Association Inc.

  14. Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration

    Directory of Open Access Journals (Sweden)

    Annie M. Wu

    2015-01-01

    Full Text Available Purpose. To evaluate the methodological quality of age-related macular degeneration (AMD clinical practice guidelines (CPGs. Methods. AMD CPGs published by the American Academy of Ophthalmology (AAO and Royal College of Ophthalmologists (RCO were appraised by independent reviewers using the Appraisal of Guidelines for Research and Evaluation (AGREE II instrument, which comprises six domains (Scope and Purpose, Stakeholder Involvement, Rigor of Development, Clarity of Presentation, Applicability, and Editorial Independence, and an Overall Assessment score summarizing methodological quality across all domains. Results. Average domain scores ranged from 35% to 83% for the AAO CPG and from 17% to 83% for the RCO CPG. Intraclass correlation coefficients for the reliability of mean scores for the AAO and RCO CPGs were 0.74 and 0.88, respectively. The strongest domains were Scope and Purpose and Clarity of Presentation. The weakest were Stakeholder Involvement (AAO and Editorial Independence (RCO. Conclusions. Future AMD CPGs can be improved by involving all relevant stakeholders in guideline development, ensuring transparency of guideline development and review methodology, improving guideline applicability with respect to economic considerations, and addressing potential conflict of interests within the development group.

  15. Equilibration of matter near the QCD critical point

    International Nuclear Information System (INIS)

    Bravina, L V; Arsene, I; Nilsson, M S; Tywoniuk, K; Zabrodin, E E

    2006-01-01

    The relaxation of hot and dense nuclear matter to local equilibrium in the central zone of heavy-ion collisions at energies around 40 A GeV is studied within the microscopic transport model. Dynamical calculations performed for the central cell in the reaction are compared to the predictions of the thermal statistical model. It is found that kinetic, thermal and chemical equilibrations of the expanding hadronic matter are nearly approached for the period of 10-18 fm/c. Within this time, the matter in the cell expands almost isentropically. It is quite interesting that in the T-μ B plane the system crosses the critical point predicted by lattice QCD calculations. Similar to the cells studied at lower (AGS) and higher (SPS, RHIC) energies, the central cell at 40 A GeV possesses negative (though small) net strangeness. Several peculiarities are observed as well. These features can be attributed to the transition from baryon-dominated to meson-dominated matter, discussed recently

  16. Superuniversal transport near a (2 +1 ) -dimensional quantum critical point

    Science.gov (United States)

    Rose, F.; Dupuis, N.

    2017-09-01

    We compute the zero-temperature conductivity in the two-dimensional quantum O (N ) model using a nonperturbative functional renormalization-group approach. At the quantum critical point we find a universal conductivity σ*/σQ (with σQ=q2/h the quantum of conductance and q the charge) in reasonable quantitative agreement with quantum Monte Carlo simulations and conformal bootstrap results. In the ordered phase the conductivity tensor is defined, when N ≥3 , by two independent elements, σA(ω ) and σB(ω ) , respectively associated with SO (N ) rotations which do and do not change the direction of the order parameter. Whereas σA(ω →0 ) corresponds to the response of a superfluid (or perfect inductance), the numerical solution of the flow equations shows that limω→0σB(ω ) /σQ=σB*/σQ is a superuniversal (i.e., N -independent) constant. These numerical results, as well as the known exact value σB*/σQ=π /8 in the large-N limit, allow us to conjecture that σB*/σQ=π /8 holds for all values of N , a result that can be understood as a consequence of gauge invariance and asymptotic freedom of the Goldstone bosons in the low-energy limit.

  17. Search for a signal on QCD critical point in central nucleusnucleus collisions

    Science.gov (United States)

    Suleymanov, M. K.; Khan, E. U.; Ahmed, K.; Haseeb, M. Q.; Tahir, F.; Huseynaliyev, Y. H.; Ajaz, M.; Khan, K. H.; Wazir, Z.

    2011-07-01

    We discuss that the QCD critical point could appear in central collisions in percolation cluster. We suggest to use the effects of nuclear transparency and that of the light nuclear production to identify the critical point.

  18. Sound absorption in solutions near the consulate critical point

    Directory of Open Access Journals (Sweden)

    В.С. Сперкач

    2005-01-01

    Full Text Available  The peculiarities of acoustical absorption coefficient in solutions of critical concentration near the critical consulate temperature have been investigated by the acoustic spectroscopy methods. The obtained data confirm conclusions of the dynamic theory of critical phenomena.

  19. 21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Hazard Analysis and Critical Control Point (HACCP... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS General Provisions § 120.8 Hazard Analysis and Critical Control Point (HACCP) plan. (a) HACCP plan. Each...

  20. Origin of chaos near critical points of quantum flow.

    Science.gov (United States)

    Efthymiopoulos, C; Kalapotharakos, C; Contopoulos, G

    2009-03-01

    The general theory of motion in the vicinity of a moving quantum nodal point (vortex) is studied in the framework of the de Broglie-Bohm trajectory method of quantum mechanics. Using an adiabatic approximation, we find that near any nodal point of an arbitrary wave function psi there is an unstable point (called the X point) in a frame of reference moving with the nodal point. The local phase portrait forms always a characteristic pattern called the "nodal-point- X -point complex." We find general formulas for this complex as well as necessary and sufficient conditions of validity of the adiabatic approximation. We demonstrate that chaos emerges from the consecutive scattering events of the orbits with nodal-point- X -point complexes. The scattering events are of two types (called type I and type II). A theoretical model is constructed yielding the local value of the Lyapunov characteristic numbers in scattering events of both types. The local Lyapunov characteristic number scales as an inverse power of the speed of the nodal point in the rest frame, implying that it scales proportionally to the size of the nodal-point- X -point complex. It is also an inverse power of the distance of a trajectory from the X point's stable manifold far from the complex. This distance plays the role of an effective "impact parameter." The results of detailed numerical experiments with different wave functions, possessing one, two, or three moving nodal points, are reported. Examples are given of regular and chaotic trajectories, and the statistics of the Lyapunov characteristic numbers of the orbits are found and compared to the number of encounter events of each orbit with the nodal-point- X -point complexes. The numerical results are in agreement with the theory, and various phenomena appearing at first as counterintuitive find a straightforward explanation.

  1. A critical appraisal of point-of-care coagulation testing in critically ill patients.

    Science.gov (United States)

    Levi, M; Hunt, B J

    2015-11-01

    Derangement of the coagulation system is a common phenomenon in critically ill patients, who may present with severe bleeding and/or conditions associated with a prothrombotic state. Monitoring of this coagulopathy can be performed with conventional coagulation assays; however, point-of-care tests have become increasingly attractive, because not only do they yield a more rapid result than clinical laboratory testing, but they may also provide a more complete picture of the condition of the hemostatic system. There are many potential areas of study and applications of point-of-care hemostatic testing in critical care, including patients who present with massive blood loss, patients with a hypercoagulable state (such as in disseminated intravascular coagulation), and monitoring of antiplatelet treatment for acute arterial thrombosis, mostly acute coronary syndromes. However, the limitations of near-patient hemostatic testing has not been fully appreciated, and are discussed here. The currently available evidence indicates that point-of-care tests may be applied to guide appropriate blood product transfusion and the use of hemostatic agents to correct the hemostatic defect or to ameliorate antithrombotic treatment. Disappointingly, however, only in cardiac surgery is there adequate evidence to show that application of near-patient thromboelastography leads to an improvement in clinically relevant outcomes, such as reductions in bleeding-related morbidity and mortality, and cost-effectiveness. More research is required to validate the utility and cost-effectiveness of near-patient hemostatic testing in other areas, especially in traumatic bleeding and postpartum hemorrhage. © 2015 International Society on Thrombosis and Haemostasis.

  2. The chiral critical point of $N_f$=3 QCD at finite density to the order $(\\mu/T)^4$

    CERN Document Server

    De Forcrand, Philippe

    2008-01-01

    QCD with three degenerate quark flavours at zero baryon density exhibits a first order thermal phase transition for small quark masses, which changes to a smooth crossover for some critical quark mass m^c_0, i.e. the chiral critical point. It is generally believed that as an (even) function of quark chemical potential, m_c(mu), the critical point moves to larger quark masses, constituting the critical endpoint of a first order phase transition in theories with m\\geq m^c_0. To test this, we consider a Taylor expansion of m_c(mu) around mu=0 and determine the first two coefficients from lattice simulations with staggered fermions on N_t=4 lattices. We employ two different techniques: a) calculating the coefficients directly from a mu=0 ensemble using a novel finite difference method, and b) fitting them to simulation data obtained for imaginary chemical potentials. The mu^2 and mu^4 coefficients are found to be negative by both methods, with consistent absolute values. Combining both methods gives evidence that...

  3. Bulk and boundary critical behavior at Lifshitz points

    Indian Academy of Sciences (India)

    expansions [59], and computer simulations [60]; and many of these theoretical predictions have been checked by careful experiments. By contrast, the application of modern field-theoretic RG approaches to the study of critical behavior at LP is a fairly recent development [41,43,46,51]. The two-loop RG analysis of critical ...

  4. Third-order gas-liquid phase transition and the nature of Andrews critical point

    Directory of Open Access Journals (Sweden)

    Tian Ma

    2011-12-01

    Full Text Available The main objective of this article is to study the nature of the Andrews critical point in the gas-liquid transition in a physical-vapor transport (PVT system. A dynamical model, consistent with the van der Waals equation near the Andrews critical point, is derived. With this model, we deduce two physical parameters, which interact exactly at the Andrews critical point, and which dictate the dynamic transition behavior near the Andrews critical point. In particular, it is shown that 1 the gas-liquid co-existence curve can be extended beyond the Andrews critical point, and 2 the transition is first order before the critical point, second-order at the critical point, and third order beyond the Andrews critical point. This clearly explains why it is hard to observe the gas-liquid phase transition beyond the Andrews critical point. Furthermore, the analysis leads naturally the introduction of a general asymmetry principle of fluctuations and the preferred transition mechanism for a thermodynamic system. The theoretical results derived in this article are in agreement with the experimental results obtained in (K. Nishikawa and T. Morita, Fluid behavior at supercritical states studied by small-angle X-ray scattering, Journal of Supercritical Fluid, 13 (1998, pp. 143-148. Also, the derived second-order transition at the critical point is consistent with the result obtained in (M. Fisher, Specific heat of a gas near the critical point, Physical Review, 136:6A (1964, pp. A1599-A1604.

  5. Liquid-Vapor Argon Isotope Fractionation from the Triple Point to the Critical Point

    DEFF Research Database (Denmark)

    Phillips, J. T.; Linderstrøm-Lang, C. U.; Bigeleisen, J.

    1972-01-01

    twice the statistical scatter of the present data, the present results for the lnα are systematically 5% lower than calculations from vapor pressure data. It is shown that T2 lnα is a linear function of (ρc−ρg), the density difference between the liquid and vapor, in the range 84–120°K......The statistical thermodynamic treatment of the equilibrium between a nonideal liquid mixture of isotopes and a vapor phase is extended to include isotope effects on the equation of state of the gas. The result is particularly simple when the isotopic partition functions in a given phase...... are compared at the same molar volume. The isotope fractionation factor α for 36Ar∕40Ar between liquid and vapor has been measured from the triple point to the critical temperature. The results are compared with previous vapor pressure data, which cover the range 84–102°K. Although the agreement is within...

  6. Comparison study of hybrid VS critical systems in point kinetics

    International Nuclear Information System (INIS)

    Ritter, G.; Tommasi, J.; Slessarev, L.; Salvatores, M.; Mouney, H.; Vergnes, J.

    1999-01-01

    An essential motivation for hybrid systems is a potentially high level of intrinsic safety against reactivity accidents. In this respect, it is necessary to assess the behaviour of an Accelerator Driven System during a TOP, LOF or TOC accident. A comparison between a critical and sub-critical reactor shows a larger sensitivity for the critical system. The ADS has an unquestionable advantage in case of TOP but a less favourable behaviour as for LOFWS type of accidents. However in the ADS cases, the beam could be easily shut off during the transient. Therefore, a part of the R and D effort should be focused on the monitoring and control of power. (author)

  7. Bulk and boundary critical behavior at Lifshitz points

    Indian Academy of Sciences (India)

    Lifshitz points are multicritical points at which a disordered phase, a homogeneous ordered phase, and a modulated ordered phase meet. Their bulk universality classes are described by natural generalizations of the standard 4 model. Analyzing these models systematically via modern field-theoretic renormalization ...

  8. Bulk and boundary critical behavior at Lifshitz points

    Indian Academy of Sciences (India)

    Abstract. Lifshitz points are multicritical points at which a disordered phase, a ho- mogeneous ordered phase, and a modulated ordered phase meet. Their bulk universality classes are described by natural generalizations of the standard φ4 model. Analyzing these models systematically via modern field-theoretic ...

  9. Effect of defects on the critical points in YBa2Cu3O7-δ

    International Nuclear Information System (INIS)

    Kwok, W. K.; Olsson, R. J.; Karapetrov, G.; Paulis, L. M.; Moulton, W. G.; Hofman, D. J.; Crabtree, G. W.

    2000-01-01

    The upper and lower critical points are investigated in untwinned YBa 2 Cu 3 O 7-δ single crystals with dilute columnar defects. Dilute columnar defects raise the upper critical point, indicating that the transition near the upper critical point is a vortex entanglement transition. The lower critical point is very sensitive to columnar defect disorder and its position can be described by a Lindemann-like criterion similar to that for melting. Dilute columnar defects induce non-linear behavior in the I-V curves of the vortex liquid state above the lower critical point, which the authors interpret as a vestige of the critical region associated with the Bose glass transition below the lower critical point

  10. Itinerant density instability at classical and quantum critical points

    Science.gov (United States)

    Feng, Yejun; van Wezel, Jasper; Flicker, Felix; Wang, Jiyang; Silevitch, D. M.; Littlewood, P. B.; Rosenbaum, T. F.

    2015-03-01

    Itinerant density waves are model systems for studying quantum critical behavior. In both the model spin- and charge-density-wave systems Cr and NbSe2, it is possible to drive a continuous quantum phase transition with critical pressures below 10 GPa. Using x-ray diffraction techniques, we are able to directly track the evolution of the ordering wave vector Q across the pressure-temperature phase diagram. We find a non-monotonic dependence of Q on pressure. Using a Landau-Ginsburg theoretical framework developed by McMillan for CDWs, we evaluate the importance of the physical terms in driving the formation of ordered states at both the thermal and quantum phase transitions. We find that the itinerant instability is the deciding factor for the emergent order, which is further influenced by the critical fluctuations in both the thermal and quantum limits.

  11. Critical types of Krasnoselskii fixed point theorems in weak topologies

    African Journals Online (AJOL)

    In this note, by means of the technique of measures of weak noncompactness, we establish a generalized form of fixed point theorem for the sum of T + S in weak topology setups of a metrizable locally convex space, where S is not weakly compact, I − T allows to be noninvertible, and T is not necessarily continuous.

  12. Universal Entanglement Entropy in 2D Conformal Quantum Critical Points

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Benjamin; Mulligan, Michael; Fradkin, Eduardo; Kim, Eun-Ah

    2008-12-05

    We study the scaling behavior of the entanglement entropy of two dimensional conformal quantum critical systems, i.e. systems with scale invariant wave functions. They include two-dimensional generalized quantum dimer models on bipartite lattices and quantum loop models, as well as the quantum Lifshitz model and related gauge theories. We show that, under quite general conditions, the entanglement entropy of a large and simply connected sub-system of an infinite system with a smooth boundary has a universal finite contribution, as well as scale-invariant terms for special geometries. The universal finite contribution to the entanglement entropy is computable in terms of the properties of the conformal structure of the wave function of these quantum critical systems. The calculation of the universal term reduces to a problem in boundary conformal field theory.

  13. Rigidity of critical points for a nonlocal Ohta-Kawasaki energy

    Science.gov (United States)

    Dipierro, Serena; Novaga, Matteo; Valdinoci, Enrico

    2017-04-01

    We investigate the shape of critical points for a free energy consisting of a nonlocal perimeter plus a nonlocal repulsive term. In particular, we prove that a volume-constrained critical point is necessarily a ball if its volume is sufficiently small with respect to its isodiametric ratio, thus extending a result previously known only for global minimizers. We also show that, at least in one-dimension, there exist critical points with arbitrarily small volume and large isodiametric ratio. This example shows that a constraint on the diameter is, in general, necessary to establish the radial symmetry of the critical points.

  14. Hazard Analysis and Critical Control Point Program for Foodservice Establishments.

    Science.gov (United States)

    Control Point ( HACCP ) inspections in foodservice operations throughout the state. The HACCP system, which first emerged in the late 1960s, is a rational...has been adopted for use in the foodservice industry. The HACCP system consists of three main components which are the: (1) Assessment of the hazards...operations. This manual was developed to assist local sanitarians in conducting HACCP inspections and in educating foodservice operators and employees

  15. Critical Control Points in the Processing of Cassava Tuber for Ighu ...

    African Journals Online (AJOL)

    Determination of the critical control points in the processing of cassava tuber into Ighu was carried out. The critical control points were determined according to the Codex guidelines for the application of the HACCP system by conducting hazard analysis. Hazard analysis involved proper examination of each processing step ...

  16. Robustness of critical points in a complex adaptive system: Effects of hedge behavior

    Science.gov (United States)

    Liang, Yuan; Huang, Ji-Ping

    2013-08-01

    In our recent papers, we have identified a class of phase transitions in the market-directed resource-allocation game, and found that there exists a critical point at which the phase transitions occur. The critical point is given by a certain resource ratio. Here, by performing computer simulations and theoretical analysis, we report that the critical point is robust against various kinds of human hedge behavior where the numbers of herds and contrarians can be varied widely. This means that the critical point can be independent of the total number of participants composed of normal agents, herds and contrarians, under some conditions. This finding means that the critical points we identified in this complex adaptive system (with adaptive agents) may also be an intensive quantity, similar to those revealed in traditional physical systems (with non-adaptive units).

  17. Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration

    Science.gov (United States)

    Garland, Donita L.; Fernandez-Godino, Rosario; Kaur, Inderjeet; Speicher, Kaye D.; Harnly, James M.; Lambris, John D.; Speicher, David W.; Pierce, Eric A.

    2014-01-01

    Macular degenerations, inherited and age related, are important causes of vision loss. Human genetic studies have suggested perturbation of the complement system is important in the pathogenesis of age-related macular degeneration. The mechanisms underlying the involvement of the complement system are not understood, although complement and inflammation have been implicated in drusen formation. Drusen are an early clinical hallmark of inherited and age-related forms of macular degeneration. We studied one of the earliest stages of macular degeneration which precedes and leads to the formation of drusen, i.e. the formation of basal deposits. The studies were done using a mouse model of the inherited macular dystrophy Doyne Honeycomb Retinal Dystrophy/Malattia Leventinese (DHRD/ML) which is caused by a p.Arg345Trp mutation in EFEMP1. The hallmark of DHRD/ML is the formation of drusen at an early age, and gene targeted Efemp1R345W/R345W mice develop extensive basal deposits. Proteomic analyses of Bruch's membrane/choroid and Bruch's membrane in the Efemp1R345W/R345W mice indicate that the basal deposits comprise normal extracellular matrix (ECM) components present in abnormal amounts. The proteomic analyses also identified significant changes in proteins with immune-related function, including complement components, in the diseased tissue samples. Genetic ablation of the complement response via generation of Efemp1R345W/R345W:C3−/− double-mutant mice inhibited the formation of basal deposits. The results demonstrate a critical role for the complement system in basal deposit formation, and suggest that complement-mediated recognition of abnormal ECM may participate in basal deposit formation in DHRD/ML and perhaps other macular degenerations. PMID:23943789

  18. Critical neutron scattering in a polymer blend above and below the critical point of demixing: Critical exponents and amplitude ratios

    DEFF Research Database (Denmark)

    Schwahn, D.; Mortensen, K.; Janssen, S.

    1994-01-01

    The critical behavior of a polymer blend was measured by small-angle neutron scattering above and below the critical temperature T-c, i.e., outside and inside the unstable region. The critical exponents and the amplitudes of the susceptibility and the correlation length were determined. For T > T...

  19. Static seals of confined flow near critical point; Etancheites statiques des ecoulements de filtration au voisinage du point critique

    Energy Technology Data Exchange (ETDEWEB)

    Khelalfa, R.; Durastanti, J.F. [Centre d' Etudes et de Recherche en Thermique, Environnement et Systemes, Paris 12, 61 avenue du General de Gaulle, 94010 Creteil Cedex (France); Darrozes, J.S. [Institut Jean Le Rond d' Alembert, Paris 6, 4 place Jussieu, 75252 Paris Cedex 05 (France)

    2011-07-01

    The assembly of metal parts that may be encountered in industry (nuclear, space, ...), creates frequently a path of leakage which can let a fluid pass. In this following study, we aim at understanding the phenomenology of a confined flow through the vicinity of critical point and its influence on the leakage rate. This sealing problem was limited to stationary and viscous situations. The leakage geometry has been assimilated to a capillary tube whose the wall temperature is fixed at the fluid critical value. A difference of pressure was imposed between a supercritical inlet and a subcritical outlet. The phenomenological approach has led to highlight the existence of a transition zone crossing the critical point. In this region of strong expansion, has shown the existence of a thermo-mechanical coupling and be taken a into account by the thermal convection joined the conduction to transport heat. It shows that the progression in fluid outwards is slowed by that cap effect. (authors)

  20. Theory of finite-entanglement scaling at one-dimensional quantum critical points.

    Science.gov (United States)

    Pollmann, Frank; Mukerjee, Subroto; Turner, Ari M; Moore, Joel E

    2009-06-26

    Studies of entanglement in many-particle systems suggest that most quantum critical ground states have infinitely more entanglement than noncritical states. Standard algorithms for one-dimensional systems construct model states with limited entanglement, which are a worse approximation to quantum critical states than to others. We give a quantitative theory of previously observed scaling behavior resulting from finite entanglement at quantum criticality. Finite-entanglement scaling in one-dimensional systems is governed not by the scaling dimension of an operator but by the "central charge" of the critical point. An important ingredient is the universal distribution of density-matrix eigenvalues at a critical point [P. Calabrese and A. Lefevre, Phys. Rev. A 78, 032329 (2008)10.1103/PhysRevA.78.032329]. The parameter-free theory is checked against numerical scaling at several quantum critical points.

  1. Universal conductance and conductivity at critical points in integer quantum Hall systems.

    Science.gov (United States)

    Schweitzer, L; Markos, P

    2005-12-16

    The sample averaged longitudinal two-terminal conductance and the respective Kubo conductivity are calculated at quantum critical points in the integer quantum Hall regime. In the limit of large system size, both transport quantities are found to be the same within numerical uncertainty in the lowest Landau band, and , respectively. In the second-lowest Landau band, a critical conductance is obtained which indeed supports the notion of universality. However, these numbers are significantly at variance with the hitherto commonly believed value . We argue that this difference is due to the multifractal structure of critical wave functions, a property that should generically show up in the conductance at quantum critical points.

  2. Visualizing Robustness of Critical Points for 2D Time-Varying Vector Fields

    KAUST Repository

    Wang, B.

    2013-06-01

    Analyzing critical points and their temporal evolutions plays a crucial role in understanding the behavior of vector fields. A key challenge is to quantify the stability of critical points: more stable points may represent more important phenomena or vice versa. The topological notion of robustness is a tool which allows us to quantify rigorously the stability of each critical point. Intuitively, the robustness of a critical point is the minimum amount of perturbation necessary to cancel it within a local neighborhood, measured under an appropriate metric. In this paper, we introduce a new analysis and visualization framework which enables interactive exploration of robustness of critical points for both stationary and time-varying 2D vector fields. This framework allows the end-users, for the first time, to investigate how the stability of a critical point evolves over time. We show that this depends heavily on the global properties of the vector field and that structural changes can correspond to interesting behavior. We demonstrate the practicality of our theories and techniques on several datasets involving combustion and oceanic eddy simulations and obtain some key insights regarding their stable and unstable features. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and Blackwell Publishing Ltd.

  3. Seafood safety: economics of hazard analysis and Critical Control Point (HACCP) programmes

    National Research Council Canada - National Science Library

    Cato, James C

    1998-01-01

    .... This document on economic issues associated with seafood safety was prepared to complement the work of the Service in seafood technology, plant sanitation and Hazard Analysis Critical Control Point (HACCP) implementation...

  4. Fermionic quantum critical point of spinless fermions on a honeycomb lattice

    International Nuclear Information System (INIS)

    Wang, Lei; Corboz, Philippe; Troyer, Matthias

    2014-01-01

    Spinless fermions on a honeycomb lattice provide a minimal realization of lattice Dirac fermions. Repulsive interactions between nearest neighbors drive a quantum phase transition from a Dirac semimetal to a charge-density-wave state through a fermionic quantum critical point, where the coupling of the Ising order parameter to the Dirac fermions at low energy drastically affects the quantum critical behavior. Encouraged by a recent discovery (Huffman and Chandrasekharan 2014 Phys. Rev. B 89 111101) of the absence of the fermion sign problem in this model, we study the fermionic quantum critical point using the continuous-time quantum Monte Carlo method with a worm-sampling technique. We estimate the transition point V/t=1.356(1) with the critical exponents ν=0.80(3) and η=0.302(7). Compatible results for the transition point are also obtained with infinite projected entangled-pair states. (paper)

  5. Impact of resonance decays on critical point signals in net-proton fluctuations

    International Nuclear Information System (INIS)

    Bluhm, Marcus; Schaefer, Thomas; Nahrgang, Marlene; Bass, Steffen A.

    2017-01-01

    The non-monotonic beam energy dependence of the higher cumulants of net-proton fluctuations is a widely studied signature of the conjectured presence of a critical point in the QCD phase diagram. In this work we study the effect of resonance decays on critical fluctuations. We show that resonance effects reduce the signatures of critical fluctuations, but that for reasonable parameter choices critical effects in the net-proton cumulants survive. The relative role of resonance decays has a weak dependence on the order of the cumulants studied with a slightly stronger suppression of critical effects for higher-order cumulants. (orig.)

  6. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Hazard analysis and Hazard Analysis Critical... Provisions § 123.6 Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan. (a) Hazard analysis. Every processor shall conduct, or have conducted for it, a hazard analysis to determine whether...

  7. Fermi-surface collapse and dynamical scaling near a quantum-critical point

    Science.gov (United States)

    Friedemann, Sven; Oeschler, Niels; Wirth, Steffen; Krellner, Cornelius; Geibel, Christoph; Steglich, Frank; Paschen, Silke; Kirchner, Stefan; Si, Qimiao

    2010-01-01

    Quantum criticality arises when a macroscopic phase of matter undergoes a continuous transformation at zero temperature. While the collective fluctuations at quantum-critical points are being increasingly recognized as playing an important role in a wide range of quantum materials, the nature of the underlying quantum-critical excitations remains poorly understood. Here we report in-depth measurements of the Hall effect in the heavy-fermion metal YbRh2Si2, a prototypical system for quantum criticality. We isolate a rapid crossover of the isothermal Hall coefficient clearly connected to the quantum-critical point from a smooth background contribution; the latter exists away from the quantum-critical point and is detectable through our studies only over a wide range of magnetic field. Importantly, the width of the critical crossover is proportional to temperature, which violates the predictions of conventional theory and is instead consistent with an energy over temperature, E/T, scaling of the quantum-critical single-electron fluctuation spectrum. Our results provide evidence that the quantum-dynamical scaling and a critical Kondo breakdown simultaneously operate in the same material. Correspondingly, we infer that macroscopic scale-invariant fluctuations emerge from the microscopic many-body excitations associated with a collapsing Fermi-surface. This insight is expected to be relevant to the unconventional finite-temperature behavior in a broad range of strongly correlated quantum systems. PMID:20668246

  8. Shape/Phase Transitions and Critical Point Symmetries in Atomic Nuclei

    OpenAIRE

    Bonatsos, Dennis

    2008-01-01

    Shape/phase transitions in atomic nuclei have first been discovered in the framework of the Interacting Boson Approximation (IBA) model. Critical point symmetries appropriate for nuclei at the transition points have been introduced as special solutions of the Bohr Hamiltonian, stirring the introduction of additional new solutions describing wide ranges of nuclei. A short review of these recent developments will be attempted.

  9. Matter fields near quantum critical point in (2+1)-dimensional U(1) gauge theory

    International Nuclear Information System (INIS)

    Liu Guozhu; Li Wei; Cheng Geng

    2010-01-01

    We study chiral phase transition and confinement of matter fields in (2+1)-dimensional U(1) gauge theory of massless Dirac fermions and scalar bosons. The vanishing scalar boson mass, r=0, defines a quantum critical point between the Higgs phase and the Coulomb phase. We consider only the critical point r=0 and the Coulomb phase with r>0. The Dirac fermion acquires a dynamical mass when its flavor is less than certain critical value N f c , which depends quantitatively on the flavor N b and the scalar boson mass r. When N f f c , the matter fields carrying internal gauge charge are all confined if r≠0 but are deconfined at the quantum critical point r=0. The system has distinct low-energy elementary excitations at the critical point r=0 and in the Coulomb phase with r≠0. We calculate the specific heat and susceptibility of the system at r=0 and r≠0, which can help to detect the quantum critical point and to judge whether dynamical fermion mass generation takes place.

  10. Generalized correlation of latent heats of vaporization of coal liquid model compounds between their freezing points and critical points

    Energy Technology Data Exchange (ETDEWEB)

    Sivaraman, A.; Kobuyashi, R.; Mayee, J.W.

    1984-02-01

    Based on Pitzer's three-parameter corresponding states principle, the authors have developed a correlation of the latent heat of vaporization of aromatic coal liquid model compounds for a temperature range from the freezing point to the critical point. An expansion of the form L = L/sub 0/ + ..omega..L /sub 1/ is used for the dimensionless latent heat of vaporization. This model utilizes a nonanalytic functional form based on results derived from renormalization group theory of fluids in the vicinity of the critical point. A simple expression for the latent heat of vaporization L = D/sub 1/epsilon /SUP 0.3333/ + D/sub 2/epsilon /SUP 0.8333/ + D/sub 4/epsilon /SUP 1.2083/ + E/sub 1/epsilon + E/sub 2/epsilon/sup 2/ + E/sub 3/epsilon/sup 3/ is cast in a corresponding states principle correlation for coal liquid compounds. Benzene, the basic constituent of the functional groups of the multi-ring coal liquid compounds, is used as the reference compound in the present correlation. This model works very well at both low and high reduced temperatures approaching the critical point (0.02 < epsilon = (T /SUB c/ - T)/(T /SUB c/- 0.69)). About 16 compounds, including single, two, and three-ring compounds, have been tested and the percent root-mean-square deviations in latent heat of vaporization reported and estimated through the model are 0.42 to 5.27%. Tables of the coefficients of L/sub 0/ and L/sub 1/ are presented. The contributing terms of the latent heat of vaporization function are also presented in a table for small increments of epsilon.

  11. Striatonigral Degeneration

    Science.gov (United States)

    ... See More About Research The NINDS supports and conducts research on disorders of the brain and nervous system such as striatonigral degeneration. This research ... Publications Definition Striatonigral ...

  12. Critical point of a rotating Bose–Einstein condensates in optical lattice

    Energy Technology Data Exchange (ETDEWEB)

    El-Badry, Azza M., E-mail: elbadry.azza@yahoo.com; Soliman, Shemi S.M.; Hassan, Ahmed S.

    2016-06-15

    In this paper, we have considered the critical point (critical atoms’ number and the corresponding critical temperature) of rotating condensate bosons trapped in optical lattices. Our system is formed by loading three dimensional harmonically trapped boson atoms into a 1D (axial direction) or 2D (radial direction) optical lattice. The system subjected to rotating with angular velocity Ω around to the axial direction z-axis. We employ the semiclassical approximation to calculate the critical point. Effects of the optical lattice depth, direction (axial or radial) and the rotation rate on the critical point are investigated using the semiclassical approximation. The calculated results showed that the temperature dependence of the critical point is changed in an optical lattice and depends crucially on the rotation rate. The effect of the finite size for one-dimensional optical lattice case, as required by experiment, is discussed. The outcome results furnish useful qualitatively theoretical results for the future Bose–Einstein condensation experiments in such traps.

  13. Hazard analysis and critical control point (HACCP) history and conceptual overview.

    Science.gov (United States)

    Hulebak, Karen L; Schlosser, Wayne

    2002-06-01

    The concept of Hazard Analysis and Critical Control Point (HACCP) is a system that enables the production of safe meat and poultry products through the thorough analysis of production processes, identification of all hazards that are likely to occur in the production establishment, the identification of critical points in the process at which these hazards may be introduced into product and therefore should be controlled, the establishment of critical limits for control at those points, the verification of these prescribed steps, and the methods by which the processing establishment and the regulatory authority can monitor how well process control through the HACCP plan is working. The history of the development of HACCP is reviewed, and examples of practical applications of HACCP are described.

  14. Completely mixed state is a critical point for three-qubit entanglement

    International Nuclear Information System (INIS)

    Tamaryan, Sayatnova

    2011-01-01

    Pure three-qubit states have five algebraically independent and one algebraically dependent polynomial invariants under local unitary transformations and an arbitrary entanglement measure is a function of these six invariants. It is shown that if the reduced density operator of a some qubit is a multiple of the unit operator, than the geometric entanglement measure of the pure three-qubit state is absolutely independent of the polynomial invariants and is a constant for such tripartite states. Hence a one-particle completely mixed state is a critical point for the geometric measure of entanglement. -- Highlights: → Geometric measure of pure three-qubits is expressed in terms of polynomial invariants. → When one Bloch vector is zero the measure is independent of the remaining invariants. → Hence a one-particle completely mixed state is a critical point for the geometric measure. → The existence of the critical points is an inherent feature of the entanglement.

  15. Euler strut: a mechanical analogy for dynamics in the vicinity of a critical point

    International Nuclear Information System (INIS)

    Bobnar, Jaka; Podgornik, Rudolf; Susman, Katarina; Cepic, Mojca; Parsegian, V Adrian; Rand, Peter R

    2011-01-01

    An anchored elastic filament (Euler strut) under an external point load applied to its free end is a simple model for a second-order phase transition. In the static case, a load greater than the critical load causes a Euler buckling instability, leading to a change in the filament's shape. The analysis of filament dynamics with an external point load at its end shows that when approaching the critical end-load, the period of such an inverted pendulum diverges in a fashion analogous to a 'soft mode' critical slowing down in, for example, a ferroelectric phase transition of displacive type. We thus show that an advanced concept of solid state physics, i.e. 'soft mode' dynamics and critical slowing down, observable in a variety of second-order phase transitions, can be actualized in this simple mechanical system. The variable loads attached to a vertical spring allow for an experimental implementation and quantitative measurements as an illustration of this analogy.

  16. Entanglement entropy of 2D conformal quantum critical points: hearing the shape of a quantum drum.

    Science.gov (United States)

    Fradkin, Eduardo; Moore, Joel E

    2006-08-04

    The entanglement entropy of a pure quantum state of a bipartite system A union or logical sumB is defined as the von Neumann entropy of the reduced density matrix obtained by tracing over one of the two parts. In one dimension, the entanglement of critical ground states diverges logarithmically in the subsystem size, with a universal coefficient that for conformally invariant critical points is related to the central charge of the conformal field theory. We find that the entanglement entropy of a standard class of z=2 conformal quantum critical points in two spatial dimensions, in addition to a nonuniversal "area law" contribution linear in the size of the AB boundary, generically has a universal logarithmically divergent correction, which is completely determined by the geometry of the partition and by the central charge of the field theory that describes the critical wave function.

  17. Singularity of the London penetration depth at quantum critical points in superconductors.

    Science.gov (United States)

    Chowdhury, Debanjan; Swingle, Brian; Berg, Erez; Sachdev, Subir

    2013-10-11

    We present a general theory of the singularity in the London penetration depth at symmetry-breaking and topological quantum critical points within a superconducting phase. While the critical exponents and ratios of amplitudes on the two sides of the transition are universal, an overall sign depends upon the interplay between the critical theory and the underlying Fermi surface. We determine these features for critical points to spin density wave and nematic ordering, and for a topological transition between a superconductor with Z2 fractionalization and a conventional superconductor. We note implications for recent measurements of the London penetration depth in BaFe2(As(1-x)P(x))2 [K. Hashimoto et al., Science 336, 1554 (2012)].

  18. Conductivity of Weakly Disordered Metals Close to a "Ferromagnetic" Quantum Critical Point

    Science.gov (United States)

    Kastrinakis, George

    2018-01-01

    We calculate analytically the conductivity of weakly disordered metals close to a "ferromagnetic" quantum critical point in the low-temperature regime. Ferromagnetic in the sense that the effective carrier potential V(q,ω ) , due to critical fluctuations, is peaked at zero momentum q=0 . Vertex corrections, due to both critical fluctuations and impurity scattering, are explicitly considered. We find that only the vertex corrections due to impurity scattering, combined with the self-energy, generate appreciable effects as a function of the temperature T and the control parameter a, which measures the proximity to the critical point. Our results are consistent with resistivity experiments in several materials displaying typical Fermi liquid behaviour, but with a diverging prefactor of the T^2 term for small a.

  19. Communication: Analytic continuation of the virial series through the critical point using parametric approximants.

    Science.gov (United States)

    Barlow, Nathaniel S; Schultz, Andrew J; Weinstein, Steven J; Kofke, David A

    2015-08-21

    The mathematical structure imposed by the thermodynamic critical point motivates an approximant that synthesizes two theoretically sound equations of state: the parametric and the virial. The former is constructed to describe the critical region, incorporating all scaling laws; the latter is an expansion about zero density, developed from molecular considerations. The approximant is shown to yield an equation of state capable of accurately describing properties over a large portion of the thermodynamic parameter space, far greater than that covered by each treatment alone.

  20. Hazard analysis and critical control point (HACCP) for an ultrasound food processing operation.

    Science.gov (United States)

    Chemat, Farid; Hoarau, Nicolas

    2004-05-01

    Emerging technologies, such as ultrasound (US), used for food and drink production often cause hazards for product safety. Classical quality control methods are inadequate to control these hazards. Hazard analysis of critical control points (HACCP) is the most secure and cost-effective method for controlling possible product contamination or cross-contamination, due to physical or chemical hazard during production. The following case study on the application of HACCP to an US food-processing operation demonstrates how the hazards at the critical control points of the process are effectively controlled through the implementation of HACCP.

  1. Dual Superfluid-Bose-Glass Critical Point in Two Dimensions and the Universal Conductivity

    International Nuclear Information System (INIS)

    Herbut, I.F.

    1997-01-01

    The continuum version of the dual theory for a system of two-dimensional quantum disordered bosons with statistical particle-hole symmetry and at T=0 admits a new disordered critical point within the renormalization group calculation at fixed dimension. We obtain the universal conductivity and the critical exponents at the superfluid-Bose glass transition in the system: σ c =0.25(2e) 2 /h , ν=1.38 , and z=1.93 , to the lowest order in fixed-point values of the dual coupling constants. copyright 1997 The American Physical Society

  2. Pasteurised milk and implementation of HACCP (Hazard Analysis Critical Control Point

    Directory of Open Access Journals (Sweden)

    T.B Murdiati

    2004-10-01

    Full Text Available The purpose of pasteurisation is to destroy pathogen bacteria without affecting the taste, flavor, and nutritional value. A study on the implementation of HACCP (Hazard Analysis Critical Control Point in producing pasteurized milk was carried out in four processing unit of pasteurised milk, one in Jakarta, two in Bandung and one in Bogor. The critical control points in the production line were identified. Milk samples were collected from the critical points and were analysed for the total number of microbes. Antibiotic residues were detected on raw milks. The study indicated that one unit in Bandung dan one unit in Jakarta produced pasteurized milk with lower number of microbes than the other units, due to better management and control applied along the chain of production. Penisilin residues was detected in raw milk used by unit in Bogor. Six critical points and the hazard might arise in those points were identified, as well as how to prevent the hazards. Quality assurance system such as HACCP would be able to produce high quality and safety of pasteurised milk, and should be implemented gradually.

  3. Degenerate nonlinear diffusion equations

    CERN Document Server

    Favini, Angelo

    2012-01-01

    The aim of these notes is to include in a uniform presentation style several topics related to the theory of degenerate nonlinear diffusion equations, treated in the mathematical framework of evolution equations with multivalued m-accretive operators in Hilbert spaces. The problems concern nonlinear parabolic equations involving two cases of degeneracy. More precisely, one case is due to the vanishing of the time derivative coefficient and the other is provided by the vanishing of the diffusion coefficient on subsets of positive measure of the domain. From the mathematical point of view the results presented in these notes can be considered as general results in the theory of degenerate nonlinear diffusion equations. However, this work does not seek to present an exhaustive study of degenerate diffusion equations, but rather to emphasize some rigorous and efficient techniques for approaching various problems involving degenerate nonlinear diffusion equations, such as well-posedness, periodic solutions, asympt...

  4. Zero-field quantum critical point in CeCoIn5.

    Science.gov (United States)

    Tokiwa, Y; Bauer, E D; Gegenwart, P

    2013-09-06

    Quantum criticality in the normal and superconducting states of the heavy-fermion metal CeCoIn5 is studied by measurements of the magnetic Grüneisen ratio ΓH and specific heat in different field orientations and temperatures down to 50 mK. A universal temperature over magnetic field scaling of ΓH in the normal state indicates a hidden quantum critical point at zero field. Within the superconducting state, the quasiparticle entropy at constant temperature increases upon reducing the field towards zero, providing additional evidence for zero-field quantum criticality.

  5. Euler Strut: A Mechanical Analogy for Dynamics in the Vicinity of a Critical Point

    Science.gov (United States)

    Bobnar, Jaka; Susman, Katarina; Parsegian, V. Adrian; Rand, Peter R.; Cepic, Mojca; Podgornik, Rudolf

    2011-01-01

    An anchored elastic filament (Euler strut) under an external point load applied to its free end is a simple model for a second-order phase transition. In the static case, a load greater than the critical load causes a Euler buckling instability, leading to a change in the filament's shape. The analysis of filament dynamics with an external point…

  6. Breakup of a Stoner model for the two-dimensional ferromagnetic quantum critical point

    Science.gov (United States)

    Dzero, M.; Gor'kov, L. P.

    2004-03-01

    Generalization of the results by A. V. Chubukov et al. [Phys. Rev. Lett. 90, 077002 (2003)] leads to the conclusion that the ferromagnetic quantum critical point cannot be described by a Stoner model because of a strong interplay between the paramagnetic fluctuations and the Cooper channel, at least in two dimensions.

  7. Hazards and critical control points of milk produced in a research ...

    African Journals Online (AJOL)

    Hazard analyses of the milk production line and the milk produced in a Research Institute farm in Zaria were conducted to determine hazards associated with the production line and the raw milk produced, and also the critical control points. These analyses consisted of watching all the steps involved in the milking of the six ...

  8. Survey on the Possible Critical Control Points during the Production of

    African Journals Online (AJOL)

    Hazard, and critical control point (CCP) analysis was carried out during the production of balangu (a locally produced roasted meat product) in Kabuga, Gwale Local Government area of Kano State Nigeria. The analysis consisted of the aerobic mesophilic bacterial count, fungal count, and detection of E. coli, Salmonella ...

  9. Implementation of the critical points model in a SFM-FDTD code working in oblique incidence

    Energy Technology Data Exchange (ETDEWEB)

    Hamidi, M; Belkhir, A; Lamrous, O [Laboratoire de Physique et Chimie Quantique, Universite Mouloud Mammeri, Tizi-Ouzou (Algeria); Baida, F I, E-mail: omarlamrous@mail.ummto.dz [Departement d' Optique P.M. Duffieux, Institut FEMTO-ST UMR 6174 CNRS Universite de Franche-Comte, 25030 Besancon Cedex (France)

    2011-06-22

    We describe the implementation of the critical points model in a finite-difference-time-domain code working in oblique incidence and dealing with dispersive media through the split field method. Some tests are presented to validate our code in addition to an application devoted to plasmon resonance of a gold nanoparticles grating.

  10. Hierarchy of exactly solvable spin-1/2 chains with so (N)_I critical points

    NARCIS (Netherlands)

    Lahtinen, V.; Mansson, T.; Ardonne, E.

    2014-01-01

    We construct a hierarchy of exactly solvable spin-1/2 chains with so(N)1 critical points. Our construction is based on the framework of condensate-induced transitions between topological phases. We employ this framework to construct a Hamiltonian term that couples N transverse field Ising chains

  11. Improved Criteria for Acceptable Yield Point Elongation in Surface Critical Steels

    Energy Technology Data Exchange (ETDEWEB)

    Dr. David Matlock; Dr. John Speer

    2007-05-30

    Yield point elongation (YPE) is considered undesirable in surface critical applications where steel is formed since "strain lines" or Luders bands are created during forming. This project will examine in detail the formation of luders bands in industrially relevant strain states including the influence of substrate properties and coatings on Luders appearance. Mechanical testing and surface profilometry were the primary methods of investigation.

  12. Electric conductivity of alkali metal vapors in the region of critical point

    International Nuclear Information System (INIS)

    Likal'ter, A.A.

    1982-01-01

    A behaviour of alkali metal conductivity in the vicinity of a critical point has been analyzed on the base of deVeloped representations on a vapor state. A phenomenological conductivity theory has been developed, which is in a good agreement with experimental data obtained

  13. A three critical point theorem for non-smooth functionals with ...

    Indian Academy of Sciences (India)

    ... non-smooth functionals and by a few hypotheses, without any minimax inequality, the existence of at least three critical points with a uniform bound on the norms of solutions, is obtained. Also, as an application, our main theorem is used to obtain at least three anti-periodic solutions for a second order differential inclusion.

  14. Implementation of a direct procedure for critical point computations using preconditioned iterative solvers

    Czech Academy of Sciences Publication Activity Database

    Kouhia, R.; Tůma, Miroslav; Mäkinen, J.; Fedoroff, A.; Marjamäki, H.

    108-109, October (2012), s. 110-117 ISSN 0045-7949 R&D Projects: GA ČR(CZ) GAP108/11/0853 Institutional research plan: CEZ:AV0Z10300504 Keywords : non-linear eigenvalue problem * equilibrium equations * critical points * preconditioned iterations Subject RIV: BA - General Mathematics Impact factor: 1.509, year: 2012

  15. Degenerated differential pair with controllable transconductance

    NARCIS (Netherlands)

    Mensink, Clemens; Mensink, Clemens H.J.; Nauta, Bram

    1998-01-01

    A differential pair with input transistors and provided with a variable degeneration resistor. The degeneration resistor comprises a series arrangement of two branches of coupled resistors which are shunted in mutually corresponding points by respective control transistors whose gates are

  16. Magnetic-field control of quantum critical points of valence transition.

    Science.gov (United States)

    Watanabe, Shinji; Tsuruta, Atsushi; Miyake, Kazumasa; Flouquet, Jacques

    2008-06-13

    We study the mechanism of how critical end points of first-order valence transitions are controlled by a magnetic field. We show that the critical temperature is suppressed to be a quantum critical point (QCP) by a magnetic field, and unexpectedly, the QCP exhibits nonmonotonic field dependence in the ground-state phase diagram, giving rise to the emergence of metamagnetism even in the intermediate valence-crossover regime. The driving force of the field-induced QCP is clarified to be cooperative phenomena of the Zeeman and Kondo effects, which create a distinct energy scale from the Kondo temperature. This mechanism explains the peculiar magnetic response in CeIrIn(5) and the metamagnetic transition in YbXCu(4) for X=In as well as the sharp contrast between X=Ag and Cd.

  17. Quantum correction to conductivity close to ferromagnetic quantum critical point in two dimensions

    International Nuclear Information System (INIS)

    Paul, I.; Pepin, C.; Narozhny, B.N.; Maslov, D.L.

    2005-05-01

    We study the temperature dependence of the conductivity due to quantum interference processes for a two-dimensional disordered itinerant electron system close to a ferromagnetic quantum critical point. Near the quantum critical point, the cross-over between diffusive and ballistic regimes of quantum interference effects occurs at a temperature T* 1/τγ(E F τ) 2 where γ is the parameter associated with the Landau damping of the spin fluctuations, τ is the impurity scattering time, and E F is the Fermi energy. For a generic choice of parameters, T* is smaller than the nominal crossover scale 1/τ. In the ballistic quantum critical regime, the conductivity behaves as T 1/3 . (author)

  18. IMAGE-PLANE ANALYSIS OF n-POINT-MASS LENS CRITICAL CURVES AND CAUSTICS

    International Nuclear Information System (INIS)

    Danek, Kamil; Heyrovský, David

    2015-01-01

    The interpretation of gravitational microlensing events caused by planetary systems or multiple stars is based on the n-point-mass lens model. The first planets detected by microlensing were well described by the two-point-mass model of a star with one planet. By the end of 2014, four events involving three-point-mass lenses had been announced. Two of the lenses were stars with two planetary companions each; two were binary stars with a planet orbiting one component. While the two-point-mass model is well understood, the same cannot be said for lenses with three or more components. Even the range of possible critical-curve topologies and caustic geometries of the three-point-mass lens remains unknown. In this paper we provide new tools for mapping the critical-curve topology and caustic cusp number in the parameter space of n-point-mass lenses. We perform our analysis in the image plane of the lens. We show that all contours of the Jacobian are critical curves of re-scaled versions of the lens configuration. Utilizing this property further, we introduce the cusp curve to identify cusp-image positions on all contours simultaneously. In order to track cusp-number changes in caustic metamorphoses, we define the morph curve, which pinpoints the positions of metamorphosis-point images along the cusp curve. We demonstrate the usage of both curves on simple two- and three-point-mass lens examples. For the three simplest caustic metamorphoses we illustrate the local structure of the image and source planes

  19. System implementation of hazard analysis and critical control points (HACCP) in a nitrogen production plant

    International Nuclear Information System (INIS)

    Barrantes Salazar, Alexandra

    2014-01-01

    System of hazard analysis and critical control points are deployed in a production plant of liquid nitrogen. The fact that the nitrogen has become a complement to food packaging to increase shelf life, or provide a surface that protect it from manipulation, has been the main objective. Analysis of critical control points for the nitrogen production plant has been the adapted methodology. The knowledge of both the standard and the production process, as well as the on site verification process, have been necessary. In addition, all materials and/or processing units that are found in contact with the raw material or the product under study were evaluated. Such a way that the intrinsic risks of each were detected, from the physical, chemical and biological points of view according to the origin or pollution source. For each found risk was evaluated the probability of occurrence according to the frequency and gravity of it, with these variables determined was achieved the definition of the type of risk detected. In the cases that was presented a greater risk or critical, these were subjected decision tree; with which is concluded the non determination of critical control points. However, for each one of them were established the maximum permitted limits. To generate each of the results it has literature or scientific reference of reliable provenance, where is indicated properly the support of the evaluated matter. In a general way, the material matrix and the process matrix are found without critical control points; so that the project is concluded in the analysis, and it has to generate without the monitoring system and verification. To increase this project is suggested in order to cover the packaging system of gaseous nitrogen, due to it was delimited to liquid nitrogen. Furthermore, the liquid nitrogen is a 100% automated and closed process so the introduction of contaminants is very reduced, unlike the gaseous nitrogen process. (author) [es

  20. Finite Blaschke products with prescribed critical points, Stieltjes polynomials, and moment problems

    Science.gov (United States)

    Semmler, Gunter; Wegert, Elias

    2017-09-01

    The determination of a finite Blaschke product from its critical points is a well-known problem with interrelations to several other topics. Though existence and uniqueness of solutions are established for long, we present new aspects which have not yet been explored to their full extent. In particular, we show that the following three problems are equivalent: (i) determining a finite Blaschke product from its critical points, (ii) finding the equilibrium position of moveable point charges interacting with a special configuration of fixed charges, and (iii) solving a moment problem for the canonical representation of power moments on the real axis. These equivalences are not only of theoretical interest, but also open up new perspectives for the design of algorithms. For instance, the second problem is closely linked to the determination of certain Stieltjes and Van Vleck polynomials for a second order ODE and characterizes solutions as global minimizers of an energy functional.

  1. Hepatocerebral degeneration

    Science.gov (United States)

    Hepatocerebral degeneration is a brain disorder that occurs in people with liver damage. ... This condition may occur in any case of acquired liver failure, ... can damage brain tissue. Specific areas of the brain, such as ...

  2. Order parameter fluctuations at a critical point - an exact result about percolation -

    International Nuclear Information System (INIS)

    Botet, Robert

    2011-01-01

    The order parameter of the system in the critical state, is expected to undergo large non-Gaussian fluctuations. However, almost nothing is known about the mathematical forms of the possible probability distributions of the order parameter. A remarkable exception is the site-percolation on the Bethe lattice, for which the complete order-parameter distribution has been recently derived at the critical point. Surprisingly, it appears to be the Kolmogorov-Smirnov distribution, well known in very different areas of mathematical statistics. In the present paper, we explain first how this special distribution could appear naturally in the context of the critical systems, under the assumption (still virtually unstudied) of the exponential distribution of the number of domains of a given size. In a second part, we present for the first time the complete derivation of the order-parameter distribution for the critical percolation model on the Bethe lattice, thus completing a recent publication announcing this result.

  3. A rigorous calculation of the critical point from the fundamental equation of state for the water + ammonia mixture

    Energy Technology Data Exchange (ETDEWEB)

    Akasaka, Ryo [Faculty of Humanities, Kyushu Lutheran College, 3-12-16 Kurokami, Kumamoto 860-8520 (Japan)

    2009-01-15

    The critical point of the water + ammonia mixture was calculated directly from the Helmholtz free energy formulation. The calculation was performed according to the critical point criteria expressed in terms of the derivatives of the Helmholtz free energy with respect to mole numbers. Smooth critical locus linking between the critical points of pure water and ammonia was obtained. The critical locus showed a good agreement with the most reliable experimental data. Simple correlations for the critical temperature, pressure, and molar volume for a given composition were developed. The information obtained in this study is helpful for design and simulation of the cycles using the water + ammonia mixture as working fluid. (author)

  4. Evolving towards a critical point: A possible electromagnetic way in which the critical regime is reached as the rupture approaches

    Directory of Open Access Journals (Sweden)

    P. G. Kapiris

    2003-01-01

    Full Text Available In analogy to the study of critical phase transitions in statistical physics, it has been argued recently that the fracture of heterogeneous materials could be viewed as a critical phenomenon, either at laboratory or at geophysical scales. If the picture of the development of the fracture is correct one may guess that the precursors may reveal the critical approach of the main-shock. When a heterogeneous material is stretched, its evolution towards breaking is characterized by the appearance of microcracks before the final  break-up. Microcracks produce both acoustic and electromagnetic(EM emission in the frequency range from VLF to VHF. The microcracks and the associated acoustic and EM activities constitute the so-called precursors of general fracture. These precursors are detectable not only at laboratory but also at geophysical scales. VLF and VHF acoustic and EM emissions have been reported resulting from volcanic and seismic activities in various geologically distinct regions of the world. In the present work we attempt to establish the hypothesis that the evolution of the Earth's crust towards the critical point takes place not only in a mechanical but also in an electromagnetic sense. In other words, we focus on the possible electromagnetic criticality, which is reached while the catastrophic rupture in the Earth's crust approaches. Our main tool is the monitoring of micro-fractures that occur before the final breakup, by recording their radio-electromagnetic emissions. We show that the spectral power law analysis of the electromagnetic precursors reveals distinguishing signatures of underlying critical dynamics, such as: (i the emergence of memory effects; (ii the decrease with time of the anti-persistence behaviour; (iii the presence of persistence properties in the tail of the sequence of the precursors; and (iv the acceleration of the precursory electro-magnetic energy release. Moreover, the statistical analysis of the amplitudes of

  5. Towards an approach to assess critical quality points (CQPs) in food production systems : a case study on French fries production

    NARCIS (Netherlands)

    Ali, M.

    2012-01-01

    This thesis investigated how to develop an approach for the systematic and science based assessment of those points in food production systems that have a critical effect on quality; such points could be designated as critical quality points (CQPs). One of the fundamental objectives of quality

  6. Soliton phase near antiferromagnetic quantum critical point in Q1D conductors

    Science.gov (United States)

    Gor'kov, L. P.; Grigoriev, P. D.

    2005-08-01

    In frameworks of a nesting model for Q1D organic conductors at the antiferromagnetic (SDW) quantum critical point, the first-order transition separates the metallic state from the soliton phase having periodic domain structure. The low-temperature phase diagram also displays a 2nd-order transition line between the soliton and the uniformly gapped SDW phases. The results agree with the phase diagram of (TMTSF)2PF6 near critical pressure (Vuletic T. et al., Eur. Phys. J. B 25 (2002) 319). The detection of the 2nd-order transition line is discussed. We comment on superconductivity at low temperature.

  7. Phenomenological Equations Relating Various Critical Anomalies above a Cubic-to-Tetragonal Phase Transition Point

    Science.gov (United States)

    Hamano, Katsumi; Hirotsu, Shunsuke

    1980-01-01

    Phenomenological equations are derived which interrelate the anomalies in various thermodynamic quantities above the transition point of a cubic-to-tetragonal phase transition caused by an instability of a triply degenerate soft mode. The anomalous part of the Gibbs free energy is assumed to be a simple sum of the three parts which represent the contributions from the three fluctuation components. A cylindrical approximation is adopted to each of the three contributions by taking into account the symmetry of the fluctuations. The theory predicts that the adiabatic elastic compliances, s11s, s12s, and also s11s-s12s should exhibit anomalies proportional to the anomaly in the specific heat at constant pressure. This is in marked contrast with the result of the generalized Pippard equations derived by Garland, and by Janovec. The new equations are successfully tested for KMnF3, CsPbCl3, and CsPbBr3. The β-γ transition of NH4Br is also discussed.

  8. Theoretical, experimental and numerical diagnose of critical power point of thermoelectric generators

    DEFF Research Database (Denmark)

    Chen, Min; Gao, Xin

    2014-01-01

    of the critical power point in the series and parallel TEM arrays. Secondly, experiments of a series-parallel hybrid interconnected TEG are presented to clearly quantify the theoretical analyses. Finally, the hierarchical simulation, based on the SPICE (simulation program with integrated circuit emphasis......When a number of TEMs (thermoelectric modules) are connected in a series-parallel matrix and under mismatched temperature gradients, the overall maximum output power of the thermoelectric generator (TEG) may be lowered by certain TEMs with relatively smaller temperature difference. It is possible....... In experimental and numerical results, a number of critical power points are disclosed for a 2×4 parallel-serial hybrid TEM matrix, where the hot temperature mostly ranges from 120°C to 60°C....

  9. LIFE CYCLE ASSESSMENT AND HAZARD ANALYSIS AND CRITICAL CONTROL POINTS TO THE PASTA PRODUCT

    Directory of Open Access Journals (Sweden)

    Yulexis Meneses Linares

    2016-10-01

    Full Text Available The objective of this work is to combine the Life Cycle Assessment (LCA and Hazard Analysis and Critical Control Points (HACCP methodologies for the determination of risks that the food production represents to the human health and the ecosystem. The environmental performance of the production of pastas in the “Marta Abreu” Pasta Factory of Cienfuegos is assessed, where the critical control points determined by the biological dangers (mushrooms and plagues and the physical dangers (wood, paper, thread and ferromagnetic particles were the raw materials: flour, semolina and its mixtures, and the disposition and extraction of them. Resources are the most affected damage category due to the consumption of fossil fuels.

  10. Critical point of Nf=3 QCD from lattice simulations in the canonical ensemble

    International Nuclear Information System (INIS)

    Li Anyi; Alexandru, Andrei; Liu, Keh-Fei

    2011-01-01

    A canonical ensemble algorithm is employed to study the phase diagram of N f =3 QCD using lattice simulations. We lock in the desired quark number sector using an exact Fourier transform of the fermion determinant. We scan the phase space below T c and look for an S-shape structure in the chemical potential, which signals the coexistence phase of a first order phase transition in finite volume. Applying Maxwell construction, we determine the boundaries of the coexistence phase at three temperatures and extrapolate them to locate the critical point. Using an improved gauge action and improved Wilson fermions on lattices with a spatial extent of 1.8 fm and quark masses close to that of the strange, we find the critical point at T E =0.925(5)T c and baryon chemical potential μ B E =2.60(8)T c .

  11. Nanoporous Materials Can Tune the Critical Point of a Pure Substance

    Energy Technology Data Exchange (ETDEWEB)

    Braun, Efrem; Chen, Joseph J.; Schnell, Sondre K.; Lin, Li-Chiang; Reimer, Jeffrey A.; Smit, Berend

    2015-09-30

    Molecular simulations and NMR relaxometry experiments demonstrate that pure benzene or xylene confined in isoreticular metal–organic frameworks (IRMOFs) exhibit true vapor–liquid phase equilibria where the effective critical point may be reduced by tuning the structure of the MOF. Our results are consistent with vapor and liquid phases extending over many MOF unit cells. These results are counterintuitive since the MOF pore diameters are approximately the same length scale as the adsorbate molecules. As applications of these materials in catalysis, separations, and gas storage rely on the ability to tune the properties of adsorbed molecules, we anticipate that the ability to systematically control the critical point, thereby preparing spatially inhomogeneous local adsorbate densities, could add a new design tool for MOF applications.

  12. Synthesis of polyamide microcapsules and effect of critical point drying on physical aspect

    Science.gov (United States)

    Dubey, Rama; Shami, T. C.; Bhasker Rao, K. U.; Yoon, Hargsoon; Varadan, Vijay K.

    2009-02-01

    Polyamide microcapsules were synthesized at room temperature by an interfacial polymerization technique, by reaction of terephthaloyl dichloride with diethylenetriamine in an aqueous medium. Partially hydrolyzed polyvinyl alcohol was used as the emulsifier and toluene as the organic dispersed phase. For polyamide microcapsules, the drying technique has a strong influence on the physical aspect of the resulting microcapsules. In this paper the physical aspect of polyamide microcapsules was studied with various drying methods such as air, vacuum and CO2 critical point. It was observed that drying the microcapsules at room temperature under atmospheric conditions or vacuum resulted in an aggregated mass of broken microcapsules, whereas CO2 critical point drying (CPD) in a microfiltration teflon vessel preserved the spherical shape of polymer microcapsules with high collection efficiency. Similar results were observed on vertically aligned polypyrrole nanowires.

  13. Critical points of the Bose–Hubbard model with three-body local interaction

    Energy Technology Data Exchange (ETDEWEB)

    Avila, C.A.; Franco, R. [Departamento de Física, Universidad Nacional de Colombia, A.A. 5997, Bogotá (Colombia); Souza, A.M.C. [Departamento de Física, Universidade Federal de Sergipe, 49100-000 São Cristovão, SE (Brazil); Figueira, M.S. [Instituto de Física, Universidade Federal Fluminense, Av. Litorânea s/n, 24210-346 Niterói, Rio de Janeiro (Brazil); Silva-Valencia, J., E-mail: jsilvav@unal.edu.co [Departamento de Física, Universidad Nacional de Colombia, A.A. 5997, Bogotá (Colombia)

    2014-09-12

    Using the density matrix renormalization group method, we study a one-dimensional system of bosons that interact with a local three-body term. We calculate the phase diagram for higher densities, where the Mott insulator lobes are surrounded by the superfluid phase. We also show that the Mott insulator lobes always grow as a function of the density. The critical points of the Kosterlitz–Thouless transitions were determined through the von Neumann block entropy, and its dependence on the density is given by a power law with a negative exponent. - Highlights: • We studied the Bose–Hubbard model with a local three-body interaction term. • We show that the Mott insulator lobes always grow as a function of the density. • We found a power law dependence of the critical point position with the density.

  14. Classical dynamics of the Abelian Higgs model from the critical point and beyond

    Directory of Open Access Journals (Sweden)

    G.C. Katsimiga

    2015-09-01

    Full Text Available We present two different families of solutions of the U(1-Higgs model in a (1+1 dimensional setting leading to a localization of the gauge field. First we consider a uniform background (the usual vacuum, which corresponds to the fully higgsed-superconducting phase. Then we study the case of a non-uniform background in the form of a domain wall which could be relevantly close to the critical point of the associated spontaneous symmetry breaking. For both cases we obtain approximate analytical nodeless and nodal solutions for the gauge field resulting as bound states of an effective Pöschl–Teller potential created by the scalar field. The two scenaria differ only in the scale of the characteristic localization length. Numerical simulations confirm the validity of the obtained analytical solutions. Additionally we demonstrate how a kink may be used as a mediator driving the dynamics from the critical point and beyond.

  15. Relative criterion for validity of a semiclassical approach to the dynamics near quantum critical points.

    Science.gov (United States)

    Wang, Qian; Qin, Pinquan; Wang, Wen-ge

    2015-10-01

    Based on an analysis of Feynman's path integral formulation of the propagator, a relative criterion is proposed for validity of a semiclassical approach to the dynamics near critical points in a class of systems undergoing quantum phase transitions. It is given by an effective Planck constant, in the relative sense that a smaller effective Planck constant implies better performance of the semiclassical approach. Numerical tests of this relative criterion are given in the XY model and in the Dicke model.

  16. Crowd Simulations and Determining the Critical Density Point of Emergency Situations.

    Science.gov (United States)

    Khademipour, Gholamreza; Nakhaee, Nouzar; Anari, Seyed Mohammad Saberi; Sadeghi, Maryam; Ebrahimnejad, Hojjat; Sheikhbardsiri, Hojjat

    2017-12-01

    In modern societies, crowds and mass gatherings are recurrent. A combination of inadequate facilities and inefficient population management can lead to injury and death. Simulating people's behavior in crowds and mass gatherings can assist in the planning and management of gatherings, especially in emergency situations. We aimed to determine the crowd pattern and the critical density point in the grand bazaar of Kerman in Iran. We collected data by use of a census method with a questionnaire. To determine the critical density point, height and weight data were placed in the equation $\\,s\\,{\\equals}\\,\\sqrt {{{L{\\vskip -1.5pt \\,\\,\\asterisk\\,\\,}M} \\over {3600}}} $ and the outer body surface of all the individuals in the bazaar was calculated. The crowd was simulated by use of flow-based modeling. Flow rate was determined by using the equation (flow rate=density * speed). By use of SketchUp Pro software (version 8; Trimble, Sunnyvale, CA), the movement of each person and the general flow rate were simulated in the three-dimensional environment of Kerman bazaar. Our findings showed that the population critical density point in Kerman bazaar would be 6112 people. In an accident, the critical density point in Kerman bazaar would be created in about 1 minute 10 seconds after the event. It seems necessary to identify and provide solutions for reducing the risk of disasters caused by overcrowding in Kerman bazaar. It is suggested that researchers conduct studies to design safe and secure emergency evacuation of Kerman bazaar as well as proper planning for better and faster access of aid squads to this location. (Disaster Med Public Health Preparedness. 2017;11:674-680).

  17. A three critical point theorem for non-smooth functionals with ...

    Indian Academy of Sciences (India)

    application. DEFINITION 2.4. Assume. : X → R is a locally Lipschitz function. A vector u ∈ X is said to be a critical point of the functional if 0 ∈ ∂ (u), that is, ..... Then, from (3.5) we easily get for n ∈ N big enough 〈I′(un), un − u〉 < ε, that is, ... Let us introduce the data of our problem: let 1

  18. Dimensional reduction at the BEC quantum critical point in BaCuSi2O6.

    Science.gov (United States)

    Sebastian, Suchitra; Fisher, Ian; Harrison, Neil; Jaime, Marcelo; Sharma, Peter; Batista, Cristian; Balicas, Luis; Kawashima, Naoki

    2006-03-01

    We present results on the magnetic spin dimer system BaCuSi2O6, which can be tuned across a Bose-Einstein condensation (BEC) quantum critical point (QCP) to an ordered BEC of spins by applying an external magnetic field. Experimental results reveal a continuous crossover in critical scaling behaviour near the QCP from 3d to 2d BEC universality, indicating that dimensionality itself is an emergent property at the QCP of this particle density-tuneable BEC. Geometrical frustration leading to inter-layer decoupling is identified as the mechanism responsible for this unique manifestation of a lower dimensional QCP in the 3d BaCuSi2O6 spin system. While the theoretical concept of dimensional reduction has been extensively discussed in many different contexts as a route to low dimensionality in bulk materials, this is the first experimental realisation of dimensionally reduced criticality.

  19. Dielectric constant of 3He near the liquid-vapor critical point

    International Nuclear Information System (INIS)

    Doiron, T.; Meyer, H.

    1978-01-01

    High-resolution measurements of the static dielectic constant epsilon along the critical isochore are reported for 3 He in the region of the critical point. The experiments were conducted at a frequency of 1000 Hz and the purpose was to observe a divergence of (partialepsilon/partialT)/sub rhoc/ as T/sub c/ is approached from above. No evidence for a critical anomaly was found, the estimated upper bound for its integrated value being deltaepsilon approx. 4 x 10 -8 which is consistent with the theoretical estimations. Hence the recently reported is not observed in 3 He. In the Appendix, some experimental questions arising in such constant-density experiments are discussed

  20. Quantum Hall criticality and localization in graphene with short-range impurities at the Dirac point.

    Science.gov (United States)

    Gattenlöhner, S; Hannes, W-R; Ostrovsky, P M; Gornyi, I V; Mirlin, A D; Titov, M

    2014-01-17

    We explore the longitudinal conductivity of graphene at the Dirac point in a strong magnetic field with two types of short-range scatterers: adatoms that mix the valleys and "scalar" impurities that do not mix them. A scattering theory for the Dirac equation is employed to express the conductance of a graphene sample as a function of impurity coordinates; an averaging over impurity positions is then performed numerically. The conductivity σ is equal to the ballistic value 4e2/πh for each disorder realization, provided the number of flux quanta considerably exceeds the number of impurities. For weaker fields, the conductivity in the presence of scalar impurities scales to the quantum-Hall critical point with σ≃4×0.4e2/h at half filling or to zero away from half filling due to the onset of Anderson localization. For adatoms, the localization behavior is also obtained at half filling due to splitting of the critical energy by intervalley scattering. Our results reveal a complex scaling flow governed by fixed points of different symmetry classes: remarkably, all key manifestations of Anderson localization and criticality in two dimensions are observed numerically in a single setup.

  1. Quantum critical point and entanglement in a matrix-product ground state

    Science.gov (United States)

    Tribedi, Amit; Bose, Indrani

    2007-04-01

    In this paper, we study the entanglement properties of a spin-1 model, the exact ground state of which is given by a matrix product (MP) state. The model exhibits a critical point transition at a parameter value a=0 . The longitudinal and transverse correlation lengths are known to diverge as a→0 . We use three different entanglement measures S(i) (the one-site von Neumann entropy), S(i,j) (the two-body entanglement), and G(2,n) (the generalized global entanglement) to determine the entanglement content of the MP ground state as the parameter a is varied. The entanglement length, associated with S(i,j) , is found to diverge in the vicinity of the quantum critical point a=0 . The first derivative of the entanglement measure E [=S(i),S(i,j)] with respect to the parameter a also diverges. The first derivative of G(2,n) with respect to a does not diverge as a→0 but attains a maximum value at a=0 . At the quantum critical point itself all three entanglement measures become zero. We further show that multipartite correlations are involved in the quantum phase transitions at a=0 .

  2. Optical functions and critical points of dilute bismide alloys studied by spectroscopic ellipsometry

    Science.gov (United States)

    Bushell, Z. L.; Joseph, R. M.; Nattermann, L.; Ludewig, P.; Volz, K.; Keddie, J. L.; Sweeney, S. J.

    2018-01-01

    Critical point transition energies and optical functions of the novel GaAs-based dilute bismide alloys GaAsBi, GaNAsBi, and GaPAsBi were determined using spectroscopic ellipsometry. The ellipsometry data were analyzed using a parameterized semiconductor model to represent the dielectric function of the alloys as the sum of Gaussian oscillators centered on critical points in the band structure, and from this extracting the energies of those critical points. The band gap and spin-orbit splitting were measured for samples for a range of alloy compositions. The first experimental measurements of the spin-orbit splitting in the GaNAsBi quaternary alloy were obtained, which showed that it is approximately independent of N content, in agreement with theory. The real component of the refractive index in the transparent region below the band gap was found to decrease as the band gap increased for all of the alloys studied, following the usual relations for conventional semiconductors. This work provides key electronic and optical parameters for the development of photonic devices based on these novel alloys.

  3. Kinetic stability analysis of protein assembly on the center manifold around the critical point.

    Science.gov (United States)

    Tsuruyama, Tatsuaki

    2017-02-02

    Non-linear kinetic analysis is a useful method for illustration of the dynamic behavior of cellular biological systems. To date, center manifold theory (CMT) has not been sufficiently applied for stability analysis of biological systems. The aim of this study is to demonstrate the application of CMT to kinetic analysis of protein assembly and disassembly, and to propose a novel framework for nonlinear multi-parametric analysis. We propose a protein assembly model with nonlinear kinetics provided by the fluctuation in monomer concentrations during their diffusion. When the diffusion process of a monomer is self-limited to give kinetics non-linearity, numerical simulations suggest the probability that the assembly and disassembly oscillate near the critical point. We applied CMT to kinetic analysis of the center manifold around the critical point in detail, and successfully demonstrated bifurcation around the critical point, which explained the observed oscillation. The stability kinetics of the present model based on CMT illustrates a unique feature of protein assembly, namely non-linear behavior. Our findings are expected to provide methodology for analysis of biological systems.

  4. Thermal properties of ionic systems near the liquid-liquid critical point.

    Science.gov (United States)

    Méndez-Castro, Pablo; Troncoso, Jacobo; Pérez-Sánchez, Germán; Peleteiro, José; Romaní, Luis

    2011-12-07

    Isobaric heat capacity per unit volume, C(p), and excess molar enthalpy, h(E), were determined in the vicinity of the critical point for a set of binary systems formed by an ionic liquid and a molecular solvent. Moreover, and, since critical composition had to be accurately determined, liquid-liquid equilibrium curves were also obtained using a calorimetric method. The systems were selected with a view on representing, near room temperature, examples from clearly solvophobic to clearly coulombic behavior, which traditionally was related with the electric permittivity of the solvent. The chosen molecular compounds are: ethanol, 1-butanol, 1-hexanol, 1,3-dichloropropane, and diethylcarbonate, whereas ionic liquids are formed by imidazolium-based cations and tetrafluoroborate or bis-(trifluromethylsulfonyl)amide anions. The results reveal that solvophobic critical behavior-systems with molecular solvents of high dielectric permittivity-is very similar to that found for molecular binary systems. However, coulombic systems-those with low permittivity molecular solvents-show strong deviations from the results usually found for these magnitudes near the liquid-liquid phase transition. They present an extremely small critical anomaly in C(p)-several orders of magnitude lower than those typically obtained for binary mixtures-and extremely low h(E)-for one system even negative, fact not observed, up to date, for any liquid-liquid transition in the nearness of an upper critical solution temperature. © 2011 American Institute of Physics

  5. Neural avalanches at the critical point between replay and non-replay of spatiotemporal patterns.

    Directory of Open Access Journals (Sweden)

    Silvia Scarpetta

    Full Text Available We model spontaneous cortical activity with a network of coupled spiking units, in which multiple spatio-temporal patterns are stored as dynamical attractors. We introduce an order parameter, which measures the overlap (similarity between the activity of the network and the stored patterns. We find that, depending on the excitability of the network, different working regimes are possible. For high excitability, the dynamical attractors are stable, and a collective activity that replays one of the stored patterns emerges spontaneously, while for low excitability, no replay is induced. Between these two regimes, there is a critical region in which the dynamical attractors are unstable, and intermittent short replays are induced by noise. At the critical spiking threshold, the order parameter goes from zero to one, and its fluctuations are maximized, as expected for a phase transition (and as observed in recent experimental results in the brain. Notably, in this critical region, the avalanche size and duration distributions follow power laws. Critical exponents are consistent with a scaling relationship observed recently in neural avalanches measurements. In conclusion, our simple model suggests that avalanche power laws in cortical spontaneous activity may be the effect of a network at the critical point between the replay and non-replay of spatio-temporal patterns.

  6. Critical point in the phase diagram of primordial quark-gluon matter from black hole physics

    Science.gov (United States)

    Critelli, Renato; Noronha, Jorge; Noronha-Hostler, Jacquelyn; Portillo, Israel; Ratti, Claudia; Rougemont, Romulo

    2017-11-01

    Strongly interacting matter undergoes a crossover phase transition at high temperatures T ˜1012 K and zero net-baryon density. A fundamental question in the theory of strong interactions, QCD, is whether a hot and dense system of quarks and gluons displays critical phenomena when doped with more quarks than antiquarks, where net-baryon number fluctuations diverge. Recent lattice QCD work indicates that such a critical point can only occur in the baryon dense regime of the theory, which defies a description from first principles calculations. Here we use the holographic gauge/gravity correspondence to map the fluctuations of baryon charge in the dense quark-gluon liquid onto a numerically tractable gravitational problem involving the charge fluctuations of holographic black holes. This approach quantitatively reproduces ab initio results for the lowest order moments of the baryon fluctuations and makes predictions for the higher-order baryon susceptibilities and also for the location of the critical point, which is found to be within the reach of heavy-ion collision experiments.

  7. CRITICAL CONTROL POINT IDENTIFICATION THROUGH TROPHOLOGICAL MEAT PRODUCTION CHAINFROM FIELD TO FORK

    Directory of Open Access Journals (Sweden)

    A. V. Borodin

    2017-01-01

    Full Text Available  Competitive production management is impossible without comprehensive hazard monitoring and critical parameters control at every stage of food production from raw material and auxiliary materials delivery to ready product realization, which is difficult without modern IT-support. The HACCP (Hazard Analysis and Critical Control Points approach to product safety differs from ready product testing for compliance with NaTD requirements (Normative and Technical Documentation and emphasizes the importance of the process approach to monitoring at every stage of food production. Critical control points (CCP identification is a stage, where the presence of a risk of manufacturing products that are unsafe for human health is recognized and it is possible to take action to its elimination, prevention or reduction to an acceptable level. The use of soſtware package significantly increases the enterprise HACCP system efficiency. The article describes methodological bases for IT-approach to the CCP identification in the trophological meat production chain from field to fork. The algorithmic support and soſtware for the «Decision tree», which allows detecting existing hazards, identifying risks, determining CCPs and describing them, has been developed.

  8. Influences of depletion potential on vapor-liquid critical point metastability

    Directory of Open Access Journals (Sweden)

    S. Zhou

    2016-04-01

    Full Text Available Phase behavior of a neutral colloid dispersion is investigated based on an improved Asakura-Oosawa (AO model. Several observations are made: (i an increase of solvent fugacity can enlarge the fluid-solid (FS coexistence region, and this makes fugacity become a powerful factor in tuning a vapor-liquid transition (VLT critical point metastability. (ii A reducing of size ratio of the solvent versus colloid particle can enlarge the FS coexistence region as well as lower the VLT critical temperature, and a combination of the two effects makes the size ratio an extremely powerful factor adjusting the VLT critical point metastability. (iii Existence of a long-range attraction term in the effective colloid potential is not a necessary condition for occurrence of a vapor-solid transition (VST, and short-ranged oscillatory depletion potential also can induce the VST over an even broader temperature range. (iv Sensitivity of the freezing line on the size ratio is disclosed, and one can make use of the sensitivity to prepare mono-disperse colloid of well-controlled diameter by following a fractionated crystallization scheme; moreover, broadening of the FST coexistence region by raising the solvent fugacity and/or lowering the size ratio has important implication for crystallization process.

  9. Search for signatures of phase transition and critical point in heavy ion collisions

    International Nuclear Information System (INIS)

    Tokarev, M.V.; Kechechyan, A.; Alakhverdyants, A.; Zborovsky, I.

    2011-01-01

    The general concepts in the critical phenomena related with the notions of 'scaling' and 'universality' are considered. Behavior of various systems near a phase transition is displayed. Search for clear signatures of the phase transition of the nuclear matter and location of the critical point in heavy ion collisions (HIC) is discussed. The experimental data on inclusive spectra measured in HIC at RHIC and SPS over a wide range of energies s NN 1/2 = 9-200 GeV are analyzed in the framework of z-scaling. A microscopic scenario of the constituent interactions is presented. Dependence of the energy loss on the momentum of the produced hadron, energy and centrality of the collision is studied. Self-similarity of the constituent interactions described in terms of momentum fractions is used to characterize the nuclear medium by 'specific heat' and colliding nuclei by fractal dimensions. Preferable kinematical regions to search for signatures of the phase transition of the nuclear matter produced in HIC are discussed. Discontinuity of the 'specific heat' is assumed to be a signature of the phase transition and the critical point

  10. 75 FR 8239 - School Food Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP...

    Science.gov (United States)

    2010-02-24

    ... 0584-AD65 School Food Safety Program Based on Hazard Analysis and Critical Control Point Principles... Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP) was published on... school food safety program for the preparation and service of school meals served to children. The Office...

  11. Pressure induced superconductor quantum critical point in multi-band systems

    Energy Technology Data Exchange (ETDEWEB)

    Padilha, Igor T. [Instituto de Fisica, Universidade Federal Fluminense, Campus da Praia Vermelha, 24210-346 Niteroi, RJ (Brazil); Continentino, Mucio A. [Centro Brasileiro de Pesquisas Fisicas, Rua Dr. Xavier Sigaud 150, Rio de Janeiro, RJ, 22290-180 (Brazil)], E-mail: mucio@if.uff.br

    2009-10-15

    In multi-band superconductors as inter-metallic systems and heavy fermions, external pressure can reduce the critical temperature and eventually destroy superconductivity driving these systems to the normal state. In many cases this transition is continuous and is associated with a superconducting quantum critical point (SQCP). In this work we study a two-band superconductor in the presence of hybridization V. This one-body mixing term is due to the overlap of the different wave-functions. It can be tuned by external pressure and turns out as an important control parameter to study the phase diagram and the nature of the phase transitions. We use a BCS approximation and include both inter- and intra-band attractive interactions. For negligible inter-band interactions, as hybridization (pressure) increases we find a SQCP separating a superconductor from a normal state at a critical value of the hybridization V{sub c}. We obtain the behavior of the electronic specific heat close to the SQCP and the shape of the critical line as V approaches V{sub c}.

  12. Quantum Critical Point and Entanglement in a Matrix Product Ground State

    OpenAIRE

    Tribedi, Amit; Bose, Indrani

    2006-01-01

    In this paper, we study the entanglement properties of a spin-1 model the exact ground state of which is given by a Matrix Product state. The model exhibits a critical point transition at a parameter value a=0. The longitudinal and transverse correlation lengths are known to diverge as a tends to zero. We use three different entanglement measures S(i) (the one-site von Neumann entropy), S(i,j) (the two-body entanglement) and G(2,n) (the generalized global entanglement) to determine the entang...

  13. Thermodynamic and real-space structural evidence of a 2D critical point in phospholipid monolayers

    DEFF Research Database (Denmark)

    Nielsen, Lars K.; Bjørnholm, Thomas; Mouritsen, Ole G.

    2007-01-01

    The two-dimensional phase diagram of phospholipid monolayers at air-water interfaces has been constructed from Langmuir compression isotherms. The coexistence region between the solid and fluid phases of the monolayer ends at the critical temperature of the transition. The small-scale lateral...... structure of the monolayers has been imaged by atomic force microscopy in the nm to mu m range at distinct points in the phase diagram. The lateral structure is immobilized by transferring the monolayer from an air-water interface to a solid mica support using Langmuir-Blodgett techniques. A transfer...

  14. Regularity and chaos at critical points of first-order quantum phase transitions

    International Nuclear Information System (INIS)

    Macek, M.; Leviatan, A.

    2011-01-01

    We study the interplay between regular and chaotic dynamics at the critical point of a generic first-order quantum phase transition in an interacting boson model of nuclei. A classical analysis reveals a distinct behavior of the coexisting phases in a broad energy range. The dynamics is completely regular in the deformed phase and, simultaneously, strongly chaotic in the spherical phase. A quantum analysis of the spectra separates the regular states from the irregular ones, assigns them to particular phases, and discloses persisting regular rotational bands in the deformed region.

  15. Critical decision points in the management of impaired doctors: the New South Wales Medical Board program.

    Science.gov (United States)

    Wilhelm, Kay A; Reid, Alison M

    2004-10-04

    The New South Wales Medical Board has developed the Impaired Registrants Program to deal with impaired registrants (doctors and medical students) in a constructive and non-disciplinary manner; the program is now well established. The Program enables the Board to protect the public, while maintaining doctors in practice whenever possible. Disorders that commonly lead to referral of impaired doctors include alcohol and drug misuse, major depression, bipolar disorder, cognitive impairment and, less commonly, psychotic and personality disorders and anorexia nervosa. Pathways in the program are individualised according to the impact of the specific disorder, the registrant's career stage, stage of involvement in the program, insight and motivation. Critical points in the program include entry, easing of conditions, breach of conditions, return to work after suspension, and exit from the program. Decision-making at these points takes into account the nature of the impairment, compliance, professional and personal support available and the registrant's insight and motivation.

  16. Pathogen Reduction and Hazard Analysis and Critical Control Point (HACCP) systems for meat and poultry. USDA.

    Science.gov (United States)

    Hogue, A T; White, P L; Heminover, J A

    1998-03-01

    The United States Department of Agriculture (USDA) Food Safety Inspection Service (FSIS) adopted Hazard Analysis and Critical Control Point Systems and established finished product standards for Salmonella in slaughter plants to improve food safety for meat and poultry. In order to make significant improvements in food safety, measures must be taken at all points in the farm-to-table chain including production, transportation, slaughter, processing, storage, retail, and food preparation. Since pathogens can be introduced or multiplied anywhere along the continuum, success depends on consideration and comparison of intervention measures throughout the continuum. Food animal and public health veterinarians can create the necessary preventative environment that mitigates risks for food borne pathogen contamination.

  17. Evaluation of the i-STAT point-of-care analyzer in critically ill adult patients.

    Science.gov (United States)

    Steinfelder-Visscher, Jacoline; Teerenstra, Steven; Gunnewiek, Jacqueline M T Klein; Weerwind, Patrick W

    2008-03-01

    Point-of-care analyzers may benefit therapeutic decision making by reducing turn-around-time for samples. This is especially true when biochemical parameters exceed the clinical reference range, in which acute and effective treatment is essential. We therefore evaluated the analytical performance of the i-STAT point-of-care analyzer in two critically ill adult patient populations. During a 3-month period, 48 blood samples from patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) and 42 blood samples from non-cardiac patients who needed intensive care treatment were analyzed on both the i-STAT analyzer (CPB and non-CPB mode, respectively) and our laboratory analyzers (RapidLab 865/Sysmex XE-2100 instrument). The agreement analysis for quantitative data was used to compare i-STAT to RapidLab for blood gas/electrolytes and for hematocrit with the Sysmex instrument. Point-of-care electrolytes and blood gases had constant deviation, except for pH, pO2, and hematocrit. A clear linear trend in deviation of i-STAT from RapidLab was noticed for pH during CPB (r = 0.32, p = .03) and for pO2 > 10 kPa during CPB (r = -0.59, p pO2 pO2 pO2 range (10.6 pO2 range below 25% (n = 11) using the i-STAT. The i-STAT analyzer is suitable for point-of-care testing of electrolytes and blood gases in critically ill patients, except for high pO2. However, the discrepancy in hematocrit bias shows that accuracy established in one patient population cannot be automatically extrapolated to other patient populations, thus stressing the need for separate evaluation.

  18. Critical point in the QCD phase diagram for extremely strong background magnetic fields

    International Nuclear Information System (INIS)

    Endrödi, Gergely

    2015-01-01

    Lattice simulations have demonstrated that a background (electro)magnetic field reduces the chiral/deconfinement transition temperature of quantum chromodynamics for eB<1 GeV 2 . On the level of observables, this reduction manifests itself in an enhancement of the Polyakov loop and in a suppression of the light quark condensates (inverse magnetic catalysis) in the transition region. In this paper, we report on lattice simulations of 1+1+1-flavor QCD at an unprecedentedly high value of the magnetic field eB=3.25 GeV 2 . Based on the behavior of various observables, it is shown that even at this extremely strong field, inverse magnetic catalysis prevails and the transition, albeit becoming sharper, remains an analytic crossover. In addition, we develop an algorithm to directly simulate the asymptotically strong magnetic field limit of QCD. We find strong evidence for a first-order deconfinement phase transition in this limiting theory, implying the presence of a critical point in the QCD phase diagram. Based on the available lattice data, we estimate the location of the critical point.

  19. Testing to fulfill HACCP (Hazard Analysis Critical Control Points) requirements: principles and examples.

    Science.gov (United States)

    Gardner, I A

    1997-12-01

    On-farm HACCP (hazard analysis critical control points) monitoring requires cost-effective, yet accurate and reproducible tests that can determine the status of cows, milk, and the dairy environment. Tests need to be field-validated, and their limitations need to be established so that appropriate screening strategies can be initiated and test results can be rationally interpreted. For infections and residues of low prevalence, tests or testing strategies that are highly specific help to minimize false-positive results and excessive costs to the dairy industry. The determination of the numbers of samples to be tested in HACCP monitoring programs depends on the specific purpose of the test and the likely prevalence of the agent or residue at the critical control point. The absence of positive samples from a herd test should not be interpreted as freedom from a particular agent or residue unless the entire herd has been tested with a test that is 100% sensitive. The current lack of field-validated tests for most of the chemical and infectious agents of concern makes it difficult to ensure that the stated goals of HACCP programs are consistently achieved.

  20. Interactions and ``puff clustering'' close to the critical point in pipe flow

    Science.gov (United States)

    Vasudevan, Mukund; Hof, Björn

    2017-11-01

    The first turbulent structures to arise in pipe flow are puffs. Albeit transient in nature, their spreading determines if eventually turbulence becomes sustained. Due to the extremely long time scales involved in these processes it is virtually impossible to directly observe the transition and the flow patterns that are eventually assumed in the long time limit. We present a new experimental approach where, based on the memoryless nature of turbulent puffs, we continuously recreate the flow pattern exiting the pipe. These periodic boundary conditions enable us to show that the flow pattern eventually settles to a statistically steady state. While our study confirms the value of the critical point of Rec 2040 , the flow fields show that puffs interact over longer ranges than previously suspected. As a consequence puffs tend to cluster and these regions of large puff densities travel across the puff pattern in a wave like fashion. While transition in Couette flow has been shown to fall into the ``directed percolation'', pipe flow may be more complicated since long range interactions are prohibited for the percolation transition type. Extensive measurements at the critical point will be presented to clarify the nature of the transition.

  1. Adiabatic Perturbation Theory: From Landau-Zener Problem to Quenching Through a Quantum Critical Point

    Science.gov (United States)

    De Grandi, C.; Polkovnikov, A.

    Dynamics in closed systems recently attracted a lot of theoretical interest largely following experimental developments in cold atom systems (see e.g., [1] for a review). Several spectacular experiments already explored different aspects of non-equilibrium dynamics in interacting many-particle systems [2-8]. Recent theoretical works in this context focused on various topics, for instance: connection of dynamics and thermodynamics [9-11 M. Rigol, unpublished], dynamics following a sudden quench in low dimensional systems [11-23, L. Mathey and A. Polkovnikov, unpublished; A. Iucci and M.A. Cazalilla,unpublished], adiabatic dynamics near quantum critical points [24-37, D. Chowdhury et al., unpublished; K. Sengupta and D. Sen, unpublished; A.P. Itin and P. Törmä, unpublished; F. Pollmann et al., unpublished] and others. Though there is still very limited understanding of the generic aspects of non-equilibrium quantum dynamics, it has been recognized that such issues as integrability, dimensionality, universality (near critical points) can be explored to understand the non-equilibrium behavior of many-particle systems in various specific situations.

  2. Coherent inflationary dynamics for Bose-Einstein condensates crossing a quantum critical point

    Science.gov (United States)

    Feng, Lei; Clark, Logan W.; Gaj, Anita; Chin, Cheng

    2017-12-01

    Quantum phase transitions, transitions between many-body ground states, are of extensive interest in research ranging from condensed-matter physics to cosmology1-4. Key features of the phase transitions include a stage with rapidly growing new order, called inflation in cosmology5, followed by the formation of topological defects6-8. How inflation is initiated and evolves into topological defects remains a hot topic of debate. Ultracold atomic gas offers a pristine and tunable platform to investigate quantum critical dynamics9-21. We report the observation of coherent inflationary dynamics across a quantum critical point in driven Bose-Einstein condensates. The inflation manifests in the exponential growth of density waves and populations in well-resolved momentum states. After the inflation stage, extended coherent dynamics is evident in both real and momentum space. We present an intuitive description of the quantum critical dynamics in our system and demonstrate the essential role of phase fluctuations in the formation of topological defects.

  3. Core-softened fluids, water-like anomalies, and the liquid-liquid critical points.

    Science.gov (United States)

    Salcedo, Evy; de Oliveira, Alan Barros; Barraz, Ney M; Chakravarty, Charusita; Barbosa, Marcia C

    2011-07-28

    Molecular dynamics simulations are used to examine the relationship between water-like anomalies and the liquid-liquid critical point in a family of model fluids with multi-Gaussian, core-softened pair interactions. The core-softened pair interactions have two length scales, such that the longer length scale associated with a shallow, attractive well is kept constant while the shorter length scale associated with the repulsive shoulder is varied from an inflection point to a minimum of progressively increasing depth. The maximum depth of the shoulder well is chosen so that the resulting potential reproduces the oxygen-oxygen radial distribution function of the ST4 model of water. As the shoulder well depth increases, the pressure required to form the high density liquid decreases and the temperature up to which the high-density liquid is stable increases, resulting in the shift of the liquid-liquid critical point to much lower pressures and higher temperatures. To understand the entropic effects associated with the changes in the interaction potential, the pair correlation entropy is computed to show that the excess entropy anomaly diminishes when the shoulder well depth increases. Excess entropy scaling of diffusivity in this class of fluids is demonstrated, showing that decreasing strength of the excess entropy anomaly with increasing shoulder depth results in the progressive loss of water-like thermodynamic, structural and transport anomalies. Instantaneous normal mode analysis was used to index the overall curvature distribution of the fluid and the fraction of imaginary frequency modes was shown to correlate well with the anomalous behavior of the diffusivity and the pair correlation entropy. The results suggest in the case of core-softened potentials, in addition to the presence of two length scales, energetic, and entropic effects associated with local minima and curvatures of the pair interaction play an important role in determining the presence of water

  4. Kraepelin and degeneration theory.

    Science.gov (United States)

    Hoff, Paul

    2008-06-01

    Emil Kraepelin's contribution to the clinical and scientific field of psychiatry is recognized world-wide. In recent years, however, there have been a number of critical remarks on his acceptance of degeneration theory in particular and on his political opinion in general, which was said to have carried "overtones of proto-fascism" by Michael Shepherd [28]. The present paper discusses the theoretical cornerstones of Kraepelinian psychiatry with regard to their relevance for Kraepelin's attitude towards degeneration theory. This theory had gained wide influence not only in scientific, but also in philosophical and political circles in the last decades of the nineteenth century. There is no doubt that Kraepelin, on the one hand, accepted and implemented degeneration theory into the debate on etiology and pathogenesis of mental disorders. On the other hand, it is not appropriate to draw a simple and direct line from early versions of degeneration theory to the crimes of psychiatrists and politicians during the rule of national socialism. What we need, is a differentiated view, since this will be the only scientific one. Much research needs to be done here in the future, and such research will surely have a significant impact not only on the historical field, but also on the continuous debate about psychiatry, neuroscience and neurophilosophy.

  5. Point-of-care blood glucose measurement errors overestimate hypoglycaemia rates in critically ill patients.

    Science.gov (United States)

    Nya-Ngatchou, Jean-Jacques; Corl, Dawn; Onstad, Susan; Yin, Tom; Tylee, Tracy; Suhr, Louise; Thompson, Rachel E; Wisse, Brent E

    2015-02-01

    Hypoglycaemia is associated with morbidity and mortality in critically ill patients, and many hospitals have programmes to minimize hypoglycaemia rates. Recent studies have established the hypoglycaemic patient-day as a key metric and have published benchmark inpatient hypoglycaemia rates on the basis of point-of-care blood glucose data even though these values are prone to measurement errors. A retrospective, cohort study including all patients admitted to Harborview Medical Center Intensive Care Units (ICUs) during 2010 and 2011 was conducted to evaluate a quality improvement programme to reduce inappropriate documentation of point-of-care blood glucose measurement errors. Laboratory Medicine point-of-care blood glucose data and patient charts were reviewed to evaluate all episodes of hypoglycaemia. A quality improvement intervention decreased measurement errors from 31% of hypoglycaemic (measurement errors likely overestimates ICU hypoglycaemia rates and can be reduced by a quality improvement effort. The currently used hypoglycaemic patient-day metric does not evaluate recurrent or prolonged events that may be more likely to cause patient harm. The monitored patient-day as currently defined may not be the optimal denominator to determine inpatient hypoglycaemic risk. Copyright © 2014 John Wiley & Sons, Ltd.

  6. Supercritical CO2 Brayton cycle compression and control near the critical point

    International Nuclear Information System (INIS)

    Wright, S. A.; Fuller, R.; Noall, J.; Radel, R.; Vernon, M. E.; Pickard, P. S.

    2008-01-01

    This report describes the supercritical compression and control issues, the analysis, and the measured test results of a small-scale supercritical CO 2 (S-CO 2 ) compression test-loop. The test loop was developed by Sandia and is described in a companion paper in this conference. The results of these experiments will for the first time evaluate and experimentally demonstrate supercritical compression and the required compressor inlet control approaches on an appropriate scale in a series of test loops at Sandia National Laboratories. The Sandia effort is focused on the main compressor of a supercritical Brayton loop while a separate DOE Gen lV program focus is on studying similar behavior in re-compression Brayton cycles that have dual compressors. One of the main goals of this program is to develop and demonstrate the ability to design, operate, and control the supercritical compression process near the critical point due to highly non-linear behavior near this point. This Sandia supercritical test-loop uses a 50 kW radial compressor to pump supercritical CO 2 (S-CO 2 ) through an orifice and through a water-cooled gas-chiller. At the design point the compressor flow rate is 3.5 kg/s, the inlet pressure is 7, 690 kPa, the pressure ratio is 1.8, the inlet temperature is 305 K, and the shaft speed is 75, 000 rpm. The purpose of the loop is to study the compression and control issues near the critical point. To study compression we intend to compare the design code predictions for efficiency and change in enthalpy (or pressure ratio / head) of the radial compressor with the measured results from actual tests. In the tests the inlet flow, temperature, and pressure, will be varied around the critical point of CO 2 (Tc=304.2 K, and Pc=7.377 MPa). To study control, the test loop will use a variety of methods including inventory control, shaft speed control, and cooling water flow rate, and cooling water temperature control methods to set the compressor inlet temperature

  7. CANDU pressure tube leak detection by annulus gas dew point measurement. A critical review

    Energy Technology Data Exchange (ETDEWEB)

    Greening, F.R. [CTS-NA, Tiverton, ON (Canada)

    2017-03-15

    In the event of a pressure tube leak from a small through-wall crack during CANDU reactor operations, there is a regulatory requirement - referred to as Leak Before Break (LBB) - for the licensee to demonstrate that there will be sufficient time for the leak to be detected and the reactor shut down before the crack grows to the critical size for fast-uncontrolled rupture. In all currently operating CANDU reactors, worldwide, this LBB requirement is met via continuous dew point measurements of the CO{sub 2} gas circulating in the reactor's Annulus Gas System (AGS). In this paper the historical development and current status of this leak detection capability is reviewed and the use of moisture injection tests as a verification procedure is critiqued. It is concluded that these tests do not represent AGS conditions that are to be expected in the event of a real pressure tube leak.

  8. The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis

    Directory of Open Access Journals (Sweden)

    Chiara Saponaro

    2015-11-01

    Full Text Available Excessive accumulation of lipids can lead to lipotoxicity, cell dysfunction and alteration in metabolic pathways, both in adipose tissue and peripheral organs, like liver, heart, pancreas and muscle. This is now a recognized risk factor for the development of metabolic disorders, such as obesity, diabetes, fatty liver disease (NAFLD, cardiovascular diseases (CVD and hepatocellular carcinoma (HCC. The causes for lipotoxicity are not only a high fat diet but also excessive lipolysis, adipogenesis and adipose tissue insulin resistance. The aims of this review are to investigate the subtle balances that underlie lipolytic, lipogenic and oxidative pathways, to evaluate critical points and the complexities of these processes and to better understand which are the metabolic derangements resulting from their imbalance, such as type 2 diabetes and non alcoholic fatty liver disease.

  9. Critical Point Facility (CPE) Group in the Spacelab Payload Operations Control Center (SL POCC)

    Science.gov (United States)

    1992-01-01

    The primary payload for Space Shuttle Mission STS-42, launched January 22, 1992, was the International Microgravity Laboratory-1 (IML-1), a pressurized manned Spacelab module. The goal of IML-1 was to explore in depth the complex effects of weightlessness of living organisms and materials processing. Around-the-clock research was performed on the human nervous system's adaptation to low gravity and effects of microgravity on other life forms such as shrimp eggs, lentil seedlings, fruit fly eggs, and bacteria. Materials processing experiments were also conducted, including crystal growth from a variety of substances such as enzymes, mercury iodide, and a virus. The Huntsville Operations Support Center (HOSC) Spacelab Payload Operations Control Center (SL POCC) at the Marshall Space Flight Center (MSFC) was the air/ground communication channel used between the astronauts and ground control teams during the Spacelab missions. Featured is the Critical Point Facility (CPE) group in the SL POCC during STS-42, IML-1 mission.

  10. Critical Point Facility (CPF) Team in the Spacelab Payload Operations Control Center (SL POCC)

    Science.gov (United States)

    1982-01-01

    The primary payload for Space Shuttle Mission STS-42, launched January 22, 1992, was the International Microgravity Laboratory-1 (IML-1), a pressurized manned Spacelab module. The goal of IML-1 was to explore in depth the complex effects of weightlessness of living organisms and materials processing. Around-the-clock research was performed on the human nervous system's adaptation to low gravity and effects of microgravity on other life forms such as shrimp eggs, lentil seedlings, fruit fly eggs, and bacteria. Materials processing experiments were also conducted, including crystal growth from a variety of substances such as enzymes, mercury iodide, and a virus. The Huntsville Operations Support Center (HOSC) Spacelab Payload Operations Control Center (SL POCC) at the Marshall Space Flight Center (MSFC) was the air/ground communication channel used between the astronauts and ground control teams during the Spacelab missions. Featured is the Critical Point Facility (CPF) team in the SL POCC during the IML-1 mission.

  11. On the fixed points of monotonic operators in the critical case

    International Nuclear Information System (INIS)

    Engibaryan, N B

    2006-01-01

    We consider the problem of constructing positive fixed points x of monotonic operators φ acting on a cone K in a Banach space E. We assume that ||φx||≤||x||+γ, γ>0, for all x element of K. In the case when φ has a so-called non-trivial dissipation functional we construct a solution in an extension of E, which is a Banach space or a Frechet space. We consider examples in which we prove the solubility of a conservative integral equation on the half-line with a sum-difference kernel, and of a non-linear integral equation of Urysohn type in the critical case

  12. PENERAPAN SISTEM HAZARD ANALYSIS CRITICAL CONTROL POINT (HACCP PADA PROSES PEMBUATAN KERIPIK TEMPE

    Directory of Open Access Journals (Sweden)

    Rahmi Yuniarti

    2015-06-01

    Full Text Available Malang is one of the industrial centers of tempe chips. To maintain the quality and food safety, analysis is required to identify the hazards during the production process. This study was conducted to identify the hazards during the production process of tempe chips and provide recommendations for developing a HACCP system. The phases of production process of tempe chips are started from slice the tempe, move it to the kitchen, coat it with flour dough, fry it in the pan, drain it, package it, and then storage it. There are 3 types of potential hazards in terms of biological, physical, and chemical during the production process. With the CCP identification, there are three processes that have Critical Control Point. There are the process of slicing tempe, immersion of tempe into the flour mixture and draining. Recommendations for the development of HACCP systems include recommendations related to employee hygiene, supporting equipment, 5-S analysis, and the production layout.

  13. Bohr model description of the critical point for the first order shape phase transition

    Science.gov (United States)

    Budaca, R.; Buganu, P.; Budaca, A. I.

    2018-01-01

    The critical point of the shape phase transition between spherical and axially deformed nuclei is described by a collective Bohr Hamiltonian with a sextic potential having simultaneous spherical and deformed minima of the same depth. The particular choice of the potential as well as the scaled and decoupled nature of the total Hamiltonian leads to a model with a single free parameter connected to the height of the barrier which separates the two minima. The solutions are found through the diagonalization in a basis of Bessel functions. The basis is optimized for each value of the free parameter by means of a boundary deformation which assures the convergence of the solutions for a fixed basis dimension. Analyzing the spectral properties of the model, as a function of the barrier height, revealed instances with shape coexisting features which are considered for detailed numerical applications.

  14. Bohr model description of the critical point for the first order shape phase transition

    Directory of Open Access Journals (Sweden)

    R. Budaca

    2018-01-01

    Full Text Available The critical point of the shape phase transition between spherical and axially deformed nuclei is described by a collective Bohr Hamiltonian with a sextic potential having simultaneous spherical and deformed minima of the same depth. The particular choice of the potential as well as the scaled and decoupled nature of the total Hamiltonian leads to a model with a single free parameter connected to the height of the barrier which separates the two minima. The solutions are found through the diagonalization in a basis of Bessel functions. The basis is optimized for each value of the free parameter by means of a boundary deformation which assures the convergence of the solutions for a fixed basis dimension. Analyzing the spectral properties of the model, as a function of the barrier height, revealed instances with shape coexisting features which are considered for detailed numerical applications.

  15. Anomalous transport phenomena in CeCoIn{sub 5} close to quantum critical point

    Energy Technology Data Exchange (ETDEWEB)

    Onari, S. [Department of Applied Physics, Nagoya University, Nagoya 464-8603 (Japan)]. E-mail: onari@fcs.coe.nagoya-u.ac.jp; Kontani, H. [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Tanaka, Y. [Department of Applied Physics, Nagoya University, Nagoya 464-8603 (Japan)

    2007-03-15

    Various transport coefficients show striking deviations from conventional Fermi-liquid behaviors in many electron systems which are close to antiferromagnetic (AF) quantum critical points (QCP). For example, Hall coefficients and Nernst coefficients in three-dimensional heavy fermion CeCoIn{sub 5} and CeCu{sub 6-x}Au{sub x} increase remarkably at low temperatures. These temperature dependences are too strong to explain in terms of the relaxation time approximation. To elucidate the origin of these anomalous transport phenomena in three-dimensional systems, we study the role of current vertex corrections (CVC) based on the fluctuation exchange (FLEX) approximation. We find that the Hall coefficient and the Nernst coefficient strongly increase due to the CVC in the vicinity of the AF QCP, even in three-dimensional systems.

  16. Seismic precursory patterns before a cliff collapse and critical point phenomena

    Science.gov (United States)

    Amitrano, D.; Grasso, J.-R.; Senfaute, G.

    2005-01-01

    We analyse the statistical pattern of seismicity before a 1-2 103 m3 chalk cliff collapse on the Normandie ocean shore, Western France. We show that a power law acceleration of seismicity rate and energy in both 40 Hz-1.5 kHz and 2 Hz-10kHz frequency range, is defined on 3 orders of magnitude, within 2 hours from the collapse time. Simultaneously, the average size of the seismic events increases toward the time to failure. These in situ results are derived from the only station located within one rupture length distance from the rock fall rupture plane. They mimic the "critical point" like behavior recovered from physical and numerical experiments before brittle failures and tertiary creep failures. Our analysis of this first seismic monitoring data of a cliff collapse suggests that the thermodynamic phase transition models for failure may apply for cliff collapse. Copyright 2005 by the American Geophysical Union.

  17. [Economic aspects of the Italian food industry: critical points and perspectives].

    Science.gov (United States)

    Casati, D

    2012-01-01

    The Italian food industry represents 2% of GDP and employment. Its role grows considering the whole food supply chain to 3.7% of GDP and 5.7% of employment, reaching 12.5% of the European one. In terms of value added, it reaches 25% of private sector expenditure, at the second places after the house one, but 8 times more than health. The european food industry is the leading sector. Italian industry is at the 3rd place for its value added, at 5th for employment, but the first for productivity together with the French food industry. Critical points of Italian food industry are mainly connected with its structure, production composition, dependence on consumer evolution, crisis impact, internationalization of firms and leading groups, innovation.

  18. The asymptotic behaviour of a critical point reactor in the absence of a controller

    International Nuclear Information System (INIS)

    Bansal, N.K.; Borgwaldt, H.

    1976-11-01

    A method is presented to calculate the first and second moments of neutron and precursor populations for a critical reactor system described by point kinetic equations and possessing inherent reactivity fluctuations. The equations have been linearised on the assumption that the system has a large average neutron population and that the amplitude of reactivity fluctuations is sufficiently small. The reactivity noise is assumed to be band limited white with a corner frequency higher than all the time constants of the system. Explicit expressions for the exact time development of the moments have been obtained for the case of a reactor without reactivity feedback and with one group of delayed neutrons. It is found that the expected values of the neutron and delayed neutron precursor numbers tend asymptotically to stationary values, whereas the mean square deviations increase linearly with time at an extremely low rate. (orig.) [de

  19. Picture change error in quasirelativistic electron/spin density, Laplacian and bond critical points

    KAUST Repository

    Bučinský, Lukáš

    2014-06-01

    The change of picture of the quasirelativistic Hartree-Fock wave functions is considered for electron/spin densities, the negative Laplacian of electron density and the appropriate bond critical point characteristics from the Quantum Theory of Atoms In Molecules (QTAIM). [OsCl5(Hpz)]- and [RuCl5(NO)]2- transition metal complexes are considered. Both, scalar relativistic and spin-orbit effects have been accounted for using the Infinite Order Two Component (IOTC) Hamiltonian. Picture change error (PCE) correction in the electron and spin densities and the Laplacian of electron density are treated analytically. Generally, PCE is found significant only in the core region of the atoms for the electron/spin density as well as Laplacian.©2014 Elsevier B.V. All rights reserved.

  20. HACCP (Hazard Analysis Critical Control Points): is it coming to the dairy?

    Science.gov (United States)

    Cullor, J S

    1997-12-01

    The risks and consequences of foodborne and waterborne pathogens are coming to the forefront of public health concerns, and strong pressure is being applied on agriculture for immediate implementation of on-farm controls. The FDA is considering HACCP (Hazard Analysis Critical Control Points) as the new foundation for revision of the US Food Safety Assurance Program because HACCP is considered to be a science-based, systematic approach to the prevention of food safety problems. In addition, the implementation of HACCP principles permits more government oversight through requirements for standard operating procedures and additional systems for keeping records, places primary responsibility for ensuring food safety on the food manufacturer or distributor, and may assist US food companies in competing more effectively in the world market. With the HACCP-based program in place, a government investigator should be able to determine and evaluate both current and past conditions that are critical to ensuring the safety of the food produced by the facility. When this policy is brought to the production unit, the impact for producers and veterinarians will be substantial.

  1. Holographic QCD phase diagram with critical point from Einstein-Maxwell-dilaton dynamics

    Science.gov (United States)

    Knaute, J.; Yaresko, R.; Kämpfer, B.

    2018-03-01

    Supplementing the holographic Einstein-Maxwell-dilaton model of [1,2] by input of lattice QCD data for 2 + 1 flavors and physical quark masses for the equation of state and quark number susceptibility at zero baryo-chemical potential we explore the resulting phase diagram over the temperature-chemical potential plane. A first-order phase transition sets in at a temperature of about 112 MeV and a baryo-chemical potential of 612 MeV. We estimate the accuracy of the critical point position in the order of approximately 5-8% by considering parameter variations and different low-temperature asymptotics for the second-order quark number susceptibility. The critical pressure as a function of the temperature has a positive slope, i.e. the entropy per baryon jumps up when crossing the phase border line from larger values of temperature/baryo-chemical potential, thus classifying the phase transition as a gas-liquid one. The updated holographic model exhibits in- and outgoing isentropes in the vicinity of the first-order phase transition.

  2. Early warning of climate tipping points from critical slowing down: comparing methods to improve robustness.

    Science.gov (United States)

    Lenton, T M; Livina, V N; Dakos, V; van Nes, E H; Scheffer, M

    2012-03-13

    We address whether robust early warning signals can, in principle, be provided before a climate tipping point is reached, focusing on methods that seek to detect critical slowing down as a precursor of bifurcation. As a test bed, six previously analysed datasets are reconsidered, three palaeoclimate records approaching abrupt transitions at the end of the last ice age and three models of varying complexity forced through a collapse of the Atlantic thermohaline circulation. Approaches based on examining the lag-1 autocorrelation function or on detrended fluctuation analysis are applied together and compared. The effects of aggregating the data, detrending method, sliding window length and filtering bandwidth are examined. Robust indicators of critical slowing down are found prior to the abrupt warming event at the end of the Younger Dryas, but the indicators are less clear prior to the Bølling-Allerød warming, or glacial termination in Antarctica. Early warnings of thermohaline circulation collapse can be masked by inter-annual variability driven by atmospheric dynamics. However, rapidly decaying modes can be successfully filtered out by using a long bandwidth or by aggregating data. The two methods have complementary strengths and weaknesses and we recommend applying them together to improve the robustness of early warnings.

  3. Controlling organic chemical hazards in food manufacturing: a hazard analysis critical control points (HACCP) approach.

    Science.gov (United States)

    Ropkins, K; Beck, A J

    2002-08-01

    Hazard analysis by critical control points (HACCP) is a systematic approach to the identification, assessment and control of hazards. Effective HACCP requires the consideration of all hazards, i.e., chemical, microbiological and physical. However, to-date most 'in-place' HACCP procedures have tended to focus on the control of microbiological and physical food hazards. In general, the chemical component of HACCP procedures is either ignored or limited to applied chemicals, e.g., food additives and pesticides. In this paper we discuss the application of HACCP to a broader range of chemical hazards, using organic chemical contaminants as examples, and the problems that are likely to arise in the food manufacturing sector. Chemical HACCP procedures are likely to result in many of the advantages previously identified for microbiological HACCP procedures: more effective, efficient and economical than conventional end-point-testing methods. However, the high costs of analytical monitoring of chemical contaminants and a limited understanding of formulation and process optimisation as means of controlling chemical contamination of foods are likely to prevent chemical HACCP becoming as effective as microbiological HACCP.

  4. Application of hazard analysis critical control points (HACCP) to organic chemical contaminants in food.

    Science.gov (United States)

    Ropkins, K; Beck, A J

    2002-03-01

    Hazard Analysis Critical Control Points (HACCP) is a systematic approach to the identification, assessment, and control of hazards that was developed as an effective alternative to conventional end-point analysis to control food safety. It has been described as the most effective means of controlling foodborne diseases, and its application to the control of microbiological hazards has been accepted internationally. By contrast, relatively little has been reported relating to the potential use of HACCP, or HACCP-like procedures, to control chemical contaminants of food. This article presents an overview of the implementation of HACCP and discusses its application to the control of organic chemical contaminants in the food chain. Although this is likely to result in many of the advantages previously identified for microbiological HACCP, that is, more effective, efficient, and economical hazard management, a number of areas are identified that require further research and development. These include: (1) a need to refine the methods of chemical contaminant identification and risk assessment employed, (2) develop more cost-effective monitoring and control methods for routine chemical contaminant surveillance of food, and (3) improve the effectiveness of process optimization for the control of chemical contaminants in food.

  5. The implementation of a Hazard Analysis and Critical Control Point management system in a peanut butter ice cream plant

    OpenAIRE

    Yu-Ting Hung; Chi-Te Liu; I-Chen Peng; Chin Hsu; Roch-Chui Yu; Kuan-Chen Cheng

    2015-01-01

    To ensure the safety of the peanut butter ice cream manufacture, a Hazard Analysis and Critical Control Point (HACCP) plan has been designed and applied to the production process. Potential biological, chemical, and physical hazards in each manufacturing procedure were identified. Critical control points for the peanut butter ice cream were then determined as the pasteurization and freezing process. The establishment of a monitoring system, corrective actions, verification procedures, and doc...

  6. Potential Improvements of Supercritical Recompression CO2 Brayton Cycle Coupled with KALIMER-600 by Modifying Critical Point of CO2

    International Nuclear Information System (INIS)

    Jeong, Woo Seok; Lee, Jeong Ik; Jeong, Yong Hoon; No, Hee Cheon

    2010-01-01

    Most of the existing designs of a Sodium cooled Fast Reactor (SFR) have a Rankine cycle as an electric power generation cycle. This has the risk of a sodium water reaction. To prevent any hazards from a sodium water reaction, an indirect Brayton cycle using Supercritical Carbon dioxide (S-CO 2 ) as the working fluids for a SFR is an alternative approach to improve the current SFR design. The supercritical Brayton cycle is defined as a cycle with operating conditions above the critical point and the main compressor inlet condition located slightly above the critical point of working fluid. This is because the main advantage of the cycle comes from significantly decreased compressor work just above the critical point due to high density near boundary between supercritical state and subcritical state. For this reason, the minimum temperature and pressure of cycle are just above the CO 2 critical point. In other words, the critical point acts as a limitation of the lowest operating condition of the cycle. In general, lowering the minimum temperature of a thermodynamic cycle can increase the efficiency and the minimum temperature can be decreased by shifting the critical point of CO 2 as mixed with other gases. In this paper, potential enhancement of S-CO 2 cycle coupled with KALIMER-600, which has been developed at KAERI, was investigated using a developed cycle code with a gas mixture property program

  7. Semi analytical solution of point kinetic equation with source from cold start up to delayed critical

    International Nuclear Information System (INIS)

    Sathiyasheela, T.

    2009-01-01

    Point kinetics equations (P. K. E) are system of differential equations, which is solved simultaneously to get the neutron density as a function of time for a given reactivity input. P. K. E are stiff differential equations, computational solution through the conventional explicit method will give a stable consistent result only for smaller time steps. Analytical solutions are available either with step or ramp reactivity insertion without considering the source power contribution. When a reactor operates at low power, the neutron source gives a considerable contribution to the net reactor power. Similarly, when the reactor is brought to delayed critical with the presence of external source, the sub critical reactor kinetics studies with source power are important to understand the power behavior as a function of reactivity insertion rate with respect to the initial reactivity. In the present work, P.K.E with one group delayed neutron are solved analytically to determine the reactor power as a function of reactivity insertion rate in the presence of neutron source. The analytical solution is a combination of converging two infinite series. Truncated infinite series is the analytical solution of P.K E. A general formulation is made by Combining both the ramp reactivity and step reactivity solution. So that the analytical solution could be useful in analyzing either step and ramp reactivity insertion exclusively or the combination of both. This general formulation could be useful in analyzing many reactor operations, like the air bubble passing through the core, stuck rod conditions, uncontrolled withdrawal of controlled rod, discontinuous lifting of control rod, lowering of rod and etc. Results of analytical solutions are compared against the results of numerical solution which is developed based on Cohen's method. The comparisons are found to be good for all kind of positive and negative ramp reactivity insertions, with or without the combination of step reactivity

  8. Macular degeneration (image)

    Science.gov (United States)

    Macular degeneration is a disease of the retina that affects the macula in the back of the eye. ... see fine details. There are two types of macular degeneration, dry and wet. Dry macular degeneration is more ...

  9. American Macular Degeneration Foundation

    Science.gov (United States)

    ... Policy Disclaimer Contact Us Donate Store The American Macular Degeneration Foundation The American Macular Degeneration Foundation (AMDF) is ... Ed Asner Video Clip An Inspiring Her-story Macular Degeneration is the leading cause of vision loss, affecting ...

  10. Hazard analysis and critical control point to irradiated food in Brazil

    International Nuclear Information System (INIS)

    Boaratti, Maria de Fatima Guerra

    2004-01-01

    Food borne diseases, in particular gastro-intestinal infections, represent a very large group of pathologies with a strong negative impact on the health of the population because of their widespread nature. Little consideration is given to such conditions due to the fact that their symptoms are often moderate and self-limiting. This has led to a general underestimation of their importance, and consequently to incorrect practices during the preparation and preservation of food, resulting in the frequent occurrence of outbreaks involving groups of varying numbers of consumers. Despite substantial efforts in the avoidance of contamination, an upward trend in the number of outbreaks of food borne illnesses caused by non-spore forming pathogenic bacteria are reported in many countries. Good hygienic practices can reduce the level of contamination but the most important pathogens cannot presently be eliminated from most farms, nor is it possible to eliminate them by primary processing, particularly from those foods which are sold raw. Several decontamination methods exist but the most versatile treatment among them is the ionizing radiation procedure. HACCP (Hazard Analysis and Critical Control Point) is a management system in which food safety is addressed through the analysis and control of biological, chemical, and physical hazards from raw material production, procurement and handling, to manufacturing, distribution and consumption of the finished product. For successful implementation of a HACCP plan, management must be strongly committed to the HACCP concept. A firm commitment to HACCP by top management provides company employees with a sense of the importance of producing safe food. At the same time, it has to be always emphasized that, like other intervention strategies, irradiation must be applied as part of a total sanitation program. The benefits of irradiation should never be considered as an excuse for poor quality or for poor handling and storage conditions

  11. Readiness to implement Hazard Analysis and Critical Control Point (HACCP) systems in Iowa schools.

    Science.gov (United States)

    Henroid, Daniel; Sneed, Jeannie

    2004-02-01

    To evaluate current food-handling practices, food safety prerequisite programs, and employee knowledge and food safety attitudes and provide baseline data for implementing Hazard Analysis and Critical Control Point (HACCP) systems in school foodservice. One member of the research team visited each school to observe food-handling practices and assess prerequisite programs using a structured observation form. A questionnaire was used to determine employees' attitudes, knowledge, and demographic information. A convenience sample of 40 Iowa schools was recruited with input from the Iowa Department of Education. Descriptive statistics were used to summarize data. One-way analysis of variance was used to assess differences in attitudes and food safety knowledge among managers, cooks, and other foodservice employees. Multiple linear regression assessed the relationship between manager and school district demographics and the food safety practice score. Proper food-handling practices were not being followed in many schools and prerequisite food safety programs for HACCP were found to be inadequate for many school foodservice operations. School foodservice employees were found to have a significant amount of food safety knowledge (15.9+/-2.4 out of 20 possible points). School districts with managers (P=.019) and employees (P=.030) who had a food handler certificate were found to have higher food safety practice scores. Emphasis on implementing prerequisite programs in preparation for HACCP is needed in school foodservice. Training programs, both basic food safety such as ServSafe and HACCP, will support improvement of food-handling practices and implementation of prerequisite programs and HACCP.

  12. Critical points of the conformational potential energy surface of carbonic acid: H 2CO 3

    Science.gov (United States)

    Janoschek, Rudolf; Csizmadia, Imre G.

    1993-12-01

    The conformational potential energy surface E  E( T1, T2) of H 2CO 3, where T1 is the torsional angle for HO 1CO 2 and T2 is the torsional angle for O 1CO 2H, revealed that the anti—anti conformation is the global minimum. Additional local minima were also found. The next higher energy conformation was the syn—anti conformation, and a degenerate pair of right handed and left handed helical conformations were the highest on the energy scale. The syn—syn conformation turned out to be a transition structure sandwiched between the two helical conformation.

  13. Critical points of Brazil nuts: a beginning for food safety, quality control and Amazon sustainability.

    Science.gov (United States)

    Lima, Andriele M; Gonçalves, Evonnildo C; Andrade, Soraya S; Barbosa, Maria S R; Barroso, Karla F P; de Sousa, Mayara B; Borges, Larissa; Vieira, Jozé L F; Teixeira, Francisco M

    2013-03-15

    One difficulty of self-sustainability is the quality assurance of native products. This research was designed to study the risks and critical control points in the collection, handling and marketing of Brazil nuts from native forests and urban fairs in the Brazilian Amazon by characterisation of morphological aspects of fungi and posterior identification by molecular biology and determination of aflatoxins by high-performance liquid chromatography. Several corrective actions to improve product quality were found to be necessary in both sites. Growth of fungi was observed in 95% of fragments of Brazil nuts from both sites during the between-harvest period. Aflatoxin levels indicated that, although fungal growth was observed in both sites, only Brazil nuts from the native forest showed a high risk to human health (total aflatoxin level of 471.69 µg kg(-1)). This study has shown the main issues related to the process design of Brazil nuts, supporting the necessity for research on new strategies to improve the quality of nuts. Also, the habit of eating Brazil nuts stored throughout the year may represent a risk to farmers. © 2012 Society of Chemical Industry.

  14. Xenon-131 surface sensitive imaging of aerogels in liquid xenon near the critical point.

    Science.gov (United States)

    Pavlovskaya, G; Blue, A K; Gibbs, S J; Haake, M; Cros, F; Malier, L; Meersmann, T

    1999-03-01

    In recent years, optically pumped xenon-129 has received a great deal of attention as a contrast agent in gas-phase imaging. This report is about the other NMR active xenon isotope (i.e., xenon-131, S = 32) which exhibits distinctive features for imaging applications in material sciences that are not obtainable from xenon-129 (S = (1/2)). The spin dynamics of xenon-131 in gas and liquid phases is largely determined by quadrupolar interactions which depend strongly on the surface of the surrounding materials. This leads to a surface dependent dispersion of relaxation rates, which can be substantial for this isotope. The dephasing of the coherence due to quadrupolar interactions may be used to yield surface specific contrast for imaging. Although optical pumping is not practical for this isotope because of its fast quadrupolar relaxation, a high spin density of liquid xenon close to the critical point (289 K) overcomes the sensitivity problems of xenon-131. We report the first xenon-131 magnetic resonance images and have tested this technique on various meso-porous aerogels as host structures. Aerogels of different densities and changing levels of hydration can clearly be distinguished from the images obtained. Copyright 1999 Academic Press.

  15. Fluctuations in a superconducting quantum critical point of multi-band metals

    Energy Technology Data Exchange (ETDEWEB)

    Ramires, A [Instituto de Fisica, Universidade Federal Fluminense, Campus da Praia Vermelha, Niteroi, RJ, 24.210-340 (Brazil); Continentino, M A, E-mail: mucio@cbpf.br [Centro Brasileiro de Pesquisas Fisicas, Rua Dr Xavier Sigaud 150, 22290-180, Rio de Janeiro, RJ (Brazil)

    2011-03-30

    In multi-band metals quasi-particles arising from different atomic orbitals coexist at a common Fermi surface. Superconductivity in these materials may appear due to interactions within a band (intra-band) or among the distinct metallic bands (inter-band). Here we consider the suppression of superconductivity in the intra-band case due to hybridization. The fluctuations at the superconducting quantum critical point (SQCP) are obtained by calculating the response of the system to a fictitious space- and time-dependent field, which couples to the superconducting order parameter. The appearance of superconductivity is related to the divergence of a generalized susceptibility. For a single-band superconductor this coincides with the Thouless criterion. For fixed chemical potential and large hybridization, the superconducting state has many features in common with breached pair superconductivity with unpaired electrons at the Fermi surface. The T = 0 phase transition from the superconductor to the normal state is in the universality class of the density-driven Bose-Einstein condensation. For a fixed number of particles and in the strong coupling limit, the system still has an instability to the normal state with increasing hybridization.

  16. Implementation of hazard analysis and critical control point (HACCP) in dried anchovy production process

    Science.gov (United States)

    Citraresmi, A. D. P.; Wahyuni, E. E.

    2018-03-01

    The aim of this study was to inspect the implementation of Hazard Analysis and Critical Control Point (HACCP) for identification and prevention of potential hazards in the production process of dried anchovy at PT. Kelola Mina Laut (KML), Lobuk unit, Sumenep. Cold storage process is needed in each anchovy processing step in order to maintain its physical and chemical condition. In addition, the implementation of quality assurance system should be undertaken to maintain product quality. The research was conducted using a survey method, by following the whole process of making anchovy from the receiving raw materials to the packaging of final product. The method of data analysis used was descriptive analysis method. Implementation of HACCP at PT. KML, Lobuk unit, Sumenep was conducted by applying Pre Requisite Programs (PRP) and preparation stage consisting of 5 initial stages and 7 principles of HACCP. The results showed that CCP was found in boiling process flow with significant hazard of Listeria monocytogenesis bacteria and final sorting process with significant hazard of foreign material contamination in the product. Actions taken were controlling boiling temperature of 100 – 105°C for 3 - 5 minutes and training for sorting process employees.

  17. Liquid-liquid critical point in a simple analytical model of water

    Science.gov (United States)

    Urbic, Tomaz

    2016-10-01

    A statistical model for a simple three-dimensional Mercedes-Benz model of water was used to study phase diagrams. This model on a simple level describes the thermal and volumetric properties of waterlike molecules. A molecule is presented as a soft sphere with four directions in which hydrogen bonds can be formed. Two neighboring waters can interact through a van der Waals interaction or an orientation-dependent hydrogen-bonding interaction. For pure water, we explored properties such as molar volume, density, heat capacity, thermal expansion coefficient, and isothermal compressibility and found that the volumetric and thermal properties follow the same trends with temperature as in real water and are in good general agreement with Monte Carlo simulations. The model exhibits also two critical points for liquid-gas transition and transition between low-density and high-density fluid. Coexistence curves and a Widom line for the maximum and minimum in thermal expansion coefficient divides the phase space of the model into three parts: in one part we have gas region, in the second a high-density liquid, and the third region contains low-density liquid.

  18. Existence results for degenerate p(x)-Laplace equations with Leray-Lions type operators

    Science.gov (United States)

    Ho, Ky; Sim, Inbo

    2017-01-01

    We show the various existence results for degenerate $p(x)$-Laplace equations with Leray-Lions type operators. A suitable condition on degeneracy is discussed and proofs are mainly based on direct methods and critical point theories in Calculus of Variations. In particular, we investigate the various situations of the growth rates between principal operators and nonlinearities.

  19. Critical Vulnerability: Defending the Decisive Point of United States Computer Networked Information Systems

    National Research Council Canada - National Science Library

    Virden, Roy

    2003-01-01

    .... The military's use of computer networked information systems is thus a critical strength. These systems are then critical vulnerabilities because they may lack adequate protection and are open to enemy attack...

  20. Brit Crit: Turning Points in British Rock Criticism 1960-1990

    DEFF Research Database (Denmark)

    Gudmundsson, Gestur; Lindberg, U.; Michelsen, M.

    2002-01-01

    The article examines the development of rock criticism in the United Kingdom from the perspective of a Bourdieuan field-analysis. Early British rock critics, like Nik Cohn, were international pioneers, a few years later there was a strong American influence, but British rock criticism has always ...

  1. Anomalous properties and coexistence of antiferromagnetism and superconductivity near a quantum critical point in rare-earth intermetallides

    International Nuclear Information System (INIS)

    Val’kov, V. V.; Zlotnikov, A. O.

    2013-01-01

    Mechanisms of the appearance of anomalous properties experimentally observed at the transition through the quantum critical point in rare-earth intermetallides have been studied. Quantum phase transitions are induced by the external pressure and are manifested as the destruction of the long-range antiferromagnetic order at zero temperature. The suppression of the long-range order is accompanied by an increase in the area of the Fermi surface, and the effective electron mass is strongly renormalized near the quantum critical point. It has been shown that such a renormalization is due to the reconstruction of the quasiparticle band, which is responsible for the formation of heavy fermions. It has been established that these features hold when the coexistence phase of antiferromagnetism and superconductivity is implemented near the quantum critical point.

  2. Preliminary study on hazards and critical control points of kokoro, a Nigerian indigenous fermented maize snack.

    Science.gov (United States)

    Oranusi, S; Dahunsi, S O

    2015-01-01

    The microbial and proximate composition of an indigenous snack from fermented maize was investigated. Critical control points of milling the raw materials, fermentation pH, processing temperature and time intervals during holdings in processing and storage were evaluated with a view to optimizing the product. The mean total aerobic plate count (TAPC) log10 values for samples of the finished products range from 2.07 ± 0.50 to 4.36 ± 0.10 cfu/g. Mean fungi count log10 was 2.00 ± 0.00 to 3.50 ± 0.50 while mean coliform count 1.04 ± 0.10 log10 cfu/g was detected in one of the sales outlets investigated. Bacterial and fungal species were isolated belonging to the genera Aspergillus, Rhizopus, Penicillium, Fusarium, Cephalosporium, Alternaria, Bacillus, Klebsiella, Staphylococcus, Lactobacillus, Pseudomonas, Proteus and Enterobacter. The moisture content of the samples ranged from 3.41 to 6.75%; fat content was 19.68 to 32.59%; fiber content was 1.84 to 2.78% while protein ranged from 6.76 to 9.23%. The ash and carbohydrate contents ranged from 1.97 to 2.31% and 49.21 to 61.96%, respectively. Based on the specifications by International Commission for Microbiological Specification for Foods (ICMSF), the TAPC counts of the finished products remained at low levels. However, presence of coliforms could prejudice the hygienic quality of these types of products hence, the need for quality control.

  3. Critical Watersheds: Climate Change, Tipping Points, and Energy-Water Impacts

    Science.gov (United States)

    Middleton, R. S.; Brown, M.; Coon, E.; Linn, R.; McDowell, N. G.; Painter, S. L.; Xu, C.

    2014-12-01

    Climate change, extreme climate events, and climate-induced disturbances will have a substantial and detrimental impact on terrestrial ecosystems. How ecosystems respond to these impacts will, in turn, have a significant effect on the quantity, quality, and timing of water supply for energy security, agriculture, industry, and municipal use. As a community, we lack sufficient quantitative and mechanistic understanding of the complex interplay between climate extremes (e.g., drought, floods), ecosystem dynamics (e.g., vegetation succession), and disruptive events (e.g., wildfire) to assess ecosystem vulnerabilities and to design mitigation strategies that minimize or prevent catastrophic ecosystem impacts. Through a combination of experimental and observational science and modeling, we are developing a unique multi-physics ecohydrologic framework for understanding and quantifying feedbacks between novel climate and extremes, surface and subsurface hydrology, ecosystem dynamics, and disruptive events in critical watersheds. The simulation capability integrates and advances coupled surface-subsurface hydrology from the Advanced Terrestrial Simulator (ATS), dynamic vegetation succession from the Ecosystem Demography (ED) model, and QUICFIRE, a novel wildfire behavior model developed from the FIRETEC platform. These advances are expected to make extensive contributions to the literature and to earth system modeling. The framework is designed to predict, quantify, and mitigate the impacts of climate change on vulnerable watersheds, with a focus on the US Mountain West and the energy-water nexus. This emerging capability is used to identify tipping points in watershed ecosystems, quantify impacts on downstream users, and formally evaluate mitigation efforts including forest (e.g., thinning, prescribed burns) and watershed (e.g., slope stabilization). The framework is being trained, validated, and demonstrated using field observations and remote data collections in the

  4. Detecting critical choke points for achieving Good Environmental Status in European seas

    Directory of Open Access Journals (Sweden)

    Tavis Potts

    2015-03-01

    Full Text Available Choke points are social, cultural, political, institutional, or psychological obstructions of social-ecological systems that constrain progress toward an environmental objective. Using a soft systems methodology, different types of chokes points were identified in the Outer Hebrides of Scotland, the Baltic, and the North and Mediterranean seas. The choke points were of differing types: cultural and political choke points were identified in Barra and the Mediterranean, respectively, whereas the choke points in the North Sea and Baltic Sea were dependent on differing values toward the mitigation of eutrophication. We conclude with suggestions to identify and address choke points.

  5. Stability theory of critical cases and the bifurcation points of the stationary solutions of the Lorenz model

    International Nuclear Information System (INIS)

    Bakasov, A.A.; Govorkov, B.B. Jr.

    1990-08-01

    The critical case in stability theory is the case when it is impossible to study the stability of solutions over the linear part of ordinary differential equations. This situation is usual at the bifurcation points. There exists a powerful and constructive approach to investigate the stability - the theory of critical cases created by Lyapunov. The famous Lorenz model is used in this article as an illustration of the power of the method (new results). (author). 27 refs

  6. Age-Related Macular Degeneration.

    Science.gov (United States)

    Mehta, Sonia

    2015-09-01

    Age-related macular degeneration (AMD) is the leading cause of vision loss in the elderly. AMD is diagnosed based on characteristic retinal findings in individuals older than 50. Early detection and treatment are critical in increasing the likelihood of retaining good and functional vision. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. [Powdered infant formulae preparation guide for hospitals based on Hazard Analysis and Critical Control Points (HACCP) principles].

    Science.gov (United States)

    Vargas-Leguás, H; Rodríguez Garrido, V; Lorite Cuenca, R; Pérez-Portabella, C; Redecillas Ferreiro, S; Campins Martí, M

    2009-06-01

    This guide for the preparation of powdered infant formulae in hospital environments is a collaborative work between several hospital services and is based on national and European regulations, international experts meetings and the recommendations of scientific societies. This guide also uses the Hazard Analysis and Critical Control Point principles proposed by Codex Alimentarius and emphasises effective verifying measures, microbiological controls of the process and the corrective actions when monitoring indicates that a critical control point is not under control. It is a dynamic guide and specifies the evaluation procedures that allow it to be constantly adapted.

  8. The implementation of a Hazard Analysis and Critical Control Point management system in a peanut butter ice cream plant

    Directory of Open Access Journals (Sweden)

    Yu-Ting Hung

    2015-09-01

    Full Text Available To ensure the safety of the peanut butter ice cream manufacture, a Hazard Analysis and Critical Control Point (HACCP plan has been designed and applied to the production process. Potential biological, chemical, and physical hazards in each manufacturing procedure were identified. Critical control points for the peanut butter ice cream were then determined as the pasteurization and freezing process. The establishment of a monitoring system, corrective actions, verification procedures, and documentation and record keeping were followed to complete the HACCP program. The results of this study indicate that implementing the HACCP system in food industries can effectively enhance food safety and quality while improving the production management.

  9. A systematic, critical review of manual palpation for identifying myofascial trigger points

    DEFF Research Database (Denmark)

    Myburgh, Corrie; Larsen, Anders Holsgaard; Hartvigsen, Jan

    2008-01-01

    To determine the reproducibility of manual palpation in identifying trigger points based on a systematic review of available literature.......To determine the reproducibility of manual palpation in identifying trigger points based on a systematic review of available literature....

  10. Hazard analysis and critical control point systems in the United States Department of Agriculture regulatory policy.

    Science.gov (United States)

    Billy, T J; Wachsmuth, I K

    1997-08-01

    Recent outbreaks of foodborne illness and studies by expert groups have established the need for fundamental change in the United States meat and poultry inspection programme to reduce the risk of foodborne illness. The Food Safety and Inspection Service (FSIS) of the United States Department of Agriculture (USDA) has embarked on a broad effort to bring about such change, with particular emphasis on the reduction of pathogenic micro-organisms in raw meat and poultry products. The publication on 25 July 1996 of the Final Rule on pathogen reduction and hazard analysis and critical control point (HACCP) systems was a major milestone in the FSIS strategy for change. The Final Rule provides a framework for change and clarifies the respective roles of industry and government in ensuring the safety of meat and poultry products. With the implementation of this Final Rule underway, the FSIS has been exploring ways in which slaughter inspection carried out under an HACCP-based system can be changed so that food safety risks are addressed more adequately and the allocation of inspection resources is improved further. In addition, the FSIS is broadening the focus of food safety activities to extend beyond slaughter and processing plants by working with industry, academia and other government agencies. Such co-operation should lead to the development of measures to improve food safety before animals reach the slaughter plant and after products leave the inspected establishment for distribution to the retail level. For the future, the FSIS believes that quantitative risk assessments will be at the core of food safety activities. Risk assessments provide the most effective means of identifying how specific pathogens and other hazards may be encountered throughout the farm-to-table chain and of measuring the potential impact of various interventions. In addition, these assessments will be used in the development and evaluation of HACCP systems. The FSIS is currently conducting a

  11. Higher moments of net kaon multiplicity distributions at RHIC energies for the search of QCD Critical Point at STAR

    Directory of Open Access Journals (Sweden)

    Sarkar Amal

    2013-11-01

    Full Text Available In this paper we report the measurements of the various moments mean (M, standard deviation (σ skewness (S and kurtosis (κ of the net-Kaon multiplicity distribution at midrapidity from Au+Au collisions at √sNN = 7.7 to 200 GeV in the STAR experiment at RHIC in an effort to locate the critical point in the QCD phase diagram. These moments and their products are related to the thermodynamic susceptibilities of conserved quantities such as net baryon number, net charge, and net strangeness as also to the correlation length of the system. A non-monotonic behavior of these variable indicate the presence of the critical point. In this work we also present the moments products Sσ, κσ2 of net-Kaon multiplicity distribution as a function of collision centrality and energies. The energy and the centrality dependence of higher moments of net-Kaons and their products have been compared with it0s Poisson expectation and with simulations from AMPT which does not include the critical point. From the measurement at all seven available beam energies, we find no evidence for a critical point in the QCD phase diagram for √sNN below 200 GeV.

  12. HACCP (Hazard Analysis and Critical Control Points) to guarantee safe water reuse and drinking water production--a case study.

    Science.gov (United States)

    Dewettinck, T; Van Houtte, E; Geenens, D; Van Hege, K; Verstraete, W

    2001-01-01

    To obtain a sustainable water catchment in the dune area of the Flemish west coast, the integration of treated domestic wastewater in the existing potable water production process is planned. The hygienic hazards associated with the introduction of treated domestic wastewater into the water cycle are well recognised. Therefore, the concept of HACCP (Hazard Analysis and Critical Control Points) was used to guarantee hygienically safe drinking water production. Taking into account the literature data on the removal efficiencies of the proposed advanced treatment steps with regard to enteric viruses and protozoa and after setting high quality limits based on the recent progress in quantitative risk assessment, the critical control points (CCPs) and points of attention (POAs) were identified. Based on the HACCP analysis a specific monitoring strategy was developed which focused on the control of these CCPs and POAs.

  13. A CRITICISM OF MONETARISM : WITH SOME POINTS FROM THE JAPANESE EXPERIENCE

    OpenAIRE

    BRAGUINSKY, Serguey

    1988-01-01

    The paper attempts at unifying the criticism of "classical dichotomy" made by J. A. Schumpeter and J. M. Keynes. Though Schumpeter's vision was that of the developing economy, with money being an important source of that development, while Keynes dealt primarily with an economy in a state of depression, Keynes's criticism is conjectured to presuppose the existence of the Schumpeterian world in the background, because only in this case can money play an active role by linking the past, present...

  14. Search for the QCD critical point in nuclear collisions at the CERN SPS

    CERN Document Server

    Anticic, T.; Barna, D.; Bartke, J.; Betev, L.; Bialkowska, H.; Blume, C.; Boimska, B.; Botje, M.; Bracinik, J.; Buncic, P.; Cerny, V.; Christakoglou, P.; Chung, P.; Chvala, O.; Cramer, J.G.; Dinkelaker, P.; Eckardt, V.; Fodor, Z.; Foka, P.; Friese, V.; Gazdzicki, M.; Genchev, V.; Grebieszkow, K.; Hohne, C.; Kadija, K.; Karev, A.; Kolesnikov, V.I.; Kowalski, M.; Kreps, M.; Laszlo, A.; Lacey, R.; van Leeuwen, M.; Lungwitz, B.; Makariev, M.; Malakhov, A.I.; Mateev, M.; Melkumov, G.L.; Mitrovski, M.; Mrowczynski, St.; Nicolic, V.; Palla, G.; Panagiotou, A.D.; Petridis, A.; Peryt, W.; Pikna, M.; Pluta, J.; Prindle, D.; Puhlhofer, F.; Renfordt, R.; Roland, C.; Roland, G.; Rybczynski, M.; Rybicki, A.; Sandoval, A.; Schmitz, N.; Schuster, T.; Seyboth, P.; Sikler, F.; Sitar, B.; Skrzypczak, E.; Slodkowski, M.; Stefanek, G.; Stock, R.; Strobele, H.; Susa, T.; Szuba, M.; Varga, D.; Vassiliou, M.; Veres, G.I.; Vesztergombi, G.; Vranic, D.; Wlodarczyk, Z.; Antoniou, N.G.; Diakonos, F.K.; Mavromanolakis, G.

    2010-01-01

    Pion production in nuclear collisions at the SPS is investigated with the aim to search, in a restricted domain of the phase diagram, for power-laws in the behaviour of correlations which are compatible with critical QCD. We have analysed interactions of nuclei of different size (p+p, C+C, Si+Si, Pb+Pb) at 158A GeV adopting, as appropriate observables, scaled factorial moments in a search for intermittent fluctuations in transverse dimensions. The analysis is performed for $\\pi^+\\pi^-$ pairs with invariant mass very close to the two-pion threshold. In this sector one may capture critical fluctuations of the sigma component in a hadronic medium, even if the $\\sigma$-meson has no well defined vacuum state. Our results indicate the presence of power-law fluctuations in the freeze-out state of the Si+Si system approaching in size the prediction of critical QCD.

  15. Solvable model of quantum phase transitions and the symbolic-manipulation-based study of its multiply degenerate exceptional points and of their unfolding

    Czech Academy of Sciences Publication Activity Database

    Znojil, Miloslav

    2013-01-01

    Roč. 336, SEP (2013), s. 98-111 ISSN 0003-4916 R&D Projects: GA ČR GAP203/11/1433 Institutional support: RVO:61389005 Keywords : Non-Hermitian quantum Hamiltonian * exceptional point * phase transition * exactly solvable model Subject RIV: BE - Theoretical Physics Impact factor: 3.065, year: 2013 http://www.sciencedirect.com/science/article/pii/S0003491613001267

  16. Size-effects on the surface tension near the critical point: Monte Carlo simulations of the Lennard-Jones fluid

    Science.gov (United States)

    Goujon, Florent; Ghoufi, Aziz; Malfreyt, Patrice

    2018-02-01

    We report Monte Carlo (MC) simulations of the Lennard-Jones (LJ) fluid at the liquid-vapor interface in the critical region. A slab-based tail method is associated with the MC simulations to approach as close as possible the critical point (T∗ = 0.98 TC∗) . We investigate then the impact of system-sizes on the surface tension and coexisting densities by considering very large box dimensions for which the surface tension is independent of system-sizes at low temperatures.

  17. Analysis of van der waal equation near the critical point | Awuor ...

    African Journals Online (AJOL)

    The van der Waal equation of state is redefined in a functional manner that reveals some additional critical parameters and presents the ideal gas temperature as a lower limit to the van der Waal gas temperature. The law of corresponding states is also shown to apply to the lower limits of reduced temperatures.

  18. Educational Turning Point in Albania: No More Mechanic Parrots but Critical Thinkers

    Science.gov (United States)

    Alhasani, Mirela Dubali

    2015-01-01

    Since 2004 Albanian academics have been making efforts to establish the best Western practices of academic writing associated with critical thinking and writing skills for university students. In this article, I will shed light upon the special challenges and peculiarities the establishment of Academic Writing discipline has encountered in Albania…

  19. Critical points in the Bragg glass phase of a weakly pinned crystal of ...

    Indian Academy of Sciences (India)

    New experimental data are presented on the scan rate dependence of the magnetization hysteresis width () (∝ critical current density c()) in isothermal - scans in a weakly pinned single crystal of Ca3Rh4Sn13, which displays second magnetization peak (SMP) anomaly as distinct from the peak effect (PE).

  20. Analysis of risk factors from salmonella infections and determination of critical control points in poultry industry production chain

    Directory of Open Access Journals (Sweden)

    Velhner Maja

    2005-01-01

    Full Text Available This paper encompasses problems related to infection caused by Salmonella spp in poultry. The need to carry out adequate control measures and to provide safe food is emphasized. Using experiences from other countries, critical control points are presented in flocks during rearing and in hatcheries. In attempt to diagnose disease as early as possible and to advise proper therapy, the significance of serology monitoring is underlined. In order to produce safe food there is a need to control disease applying our Regulations concerning eradication of Salmonella spp in poultry flocks that is given in Official paper of Republic of Serbia No 6&88 and also to include serology monitoring in poultry flocks. Veterinary practitioners are expected to perform analysis of critical control points in poultry industry as well as to determine specificity and differences in production for single farms, which would enable more effective struggle with diseases in general.

  1. [Introduction of hazard analysis and critical control points (HACCP) principles at the flight catering food production plant].

    Science.gov (United States)

    Popova, A Yu; Trukhina, G M; Mikailova, O M

    In the article there is considered the quality control and safety system implemented in the one of the largest flight catering food production plant for airline passengers and flying squad. The system for the control was based on the Hazard Analysis And Critical Control Points (HACCP) principles and developed hygienic and antiepidemic measures. There is considered the identification of hazard factors at stages of the technical process. There are presented results of the analysis data of monitoring for 6 critical control points over the five-year period. The quality control and safety system permit to decline food contamination risk during acceptance, preparation and supplying of in-flight meal. There was proved the efficiency of the implemented system. There are determined further ways of harmonization and implementation for HACCP principles in the plant.

  2. The implementation of a Hazard Analysis and Critical Control Point management system in a peanut butter ice cream plant.

    Science.gov (United States)

    Hung, Yu-Ting; Liu, Chi-Te; Peng, I-Chen; Hsu, Chin; Yu, Roch-Chui; Cheng, Kuan-Chen

    2015-09-01

    To ensure the safety of the peanut butter ice cream manufacture, a Hazard Analysis and Critical Control Point (HACCP) plan has been designed and applied to the production process. Potential biological, chemical, and physical hazards in each manufacturing procedure were identified. Critical control points for the peanut butter ice cream were then determined as the pasteurization and freezing process. The establishment of a monitoring system, corrective actions, verification procedures, and documentation and record keeping were followed to complete the HACCP program. The results of this study indicate that implementing the HACCP system in food industries can effectively enhance food safety and quality while improving the production management. Copyright © 2015. Published by Elsevier B.V.

  3. Evaluation of the i-STAT point-of-care analyzer in critically ill adult patients.

    NARCIS (Netherlands)

    Steinfelder-Visscher, J.; Teerenstra, S.; Klein Gunnewiek, J.M.T.; Weerwind, P.W.

    2008-01-01

    Point-of-care analyzers may benefit therapeutic decision making by reducing turn-around-time for samples. This is especially true when biochemical parameters exceed the clinical reference range, in which acute and effective treatment is essential. We therefore evaluated the analytical performance of

  4. The critical points of the multimatrix model as the theories of 2-d W-gravity

    International Nuclear Information System (INIS)

    Awada, M.A.; Qiu, Zongan.

    1990-03-01

    We further explore the connections between the generalized KdV hierarchy, the multimatrix model and W n -gravity. We show that the Lax-pair formulation of the generalized KdV hierarchy is nothing but the Hamiltonian equations of W-gravity. Thus we demonstrate that the multicritical points of the multimatrix model are W-gravity theories. 16 refs

  5. Unearthing the African American Past: Discoveries Point to Critical Need for Diversity in Anthropology.

    Science.gov (United States)

    Manzo, Kathleen Kennedy

    1994-01-01

    Because federal construction sites must now undergo archaeological analysis, an unprecedented number of discoveries are being made about African American history, pointing up the lack of cultural diversity in anthropologists. Efforts are being made to recruit minority students into the field and provide adequate support for their progress. (MSE)

  6. Hazard analysis and critical control points among Chinese food business operators

    Directory of Open Access Journals (Sweden)

    Stefano Saccares

    2014-09-01

    Full Text Available The purpose of the present paper is to highlight some critical situations emerged during the implementation of long-term projects locally managed by Prevention Services, to control some manufacturing companies in Rome and Prato, Central Italy. In particular, some critical issues on the application of selfcontrol in marketing and catering held by Chinese operators are underlined. The study showed serious flaws in preparing and controlling of manuals for good hygiene practice, participating of the consultants among food business operators (FBOs to the control of the procedures. Only after regular actions by the Prevention Services, there have been satisfying results. This confirms the need to have qualified and expert partners able to promptly act among FBOs and to give adequate support to authorities in charge in order to guarantee food safety.

  7. First-Order Interfacial Transformations with a Critical Point: Breaking the Symmetry at a Symmetric Tilt Grain Boundary

    Science.gov (United States)

    Yang, Shengfeng; Zhou, Naixie; Zheng, Hui; Ong, Shyue Ping; Luo, Jian

    2018-02-01

    First-order interfacial phaselike transformations that break the mirror symmetry of the symmetric ∑5 (210 ) tilt grain boundary (GB) are discovered by combining a modified genetic algorithm with hybrid Monte Carlo and molecular dynamics simulations. Density functional theory calculations confirm this prediction. This first-order coupled structural and adsorption transformation, which produces two variants of asymmetric bilayers, vanishes at an interfacial critical point. A GB complexion (phase) diagram is constructed via semigrand canonical ensemble atomistic simulations for the first time.

  8. Medication overuse headache: a critical review of end points in recent follow-up studies

    DEFF Research Database (Denmark)

    Hagen, Knut; Jensen, Rigmor; Bøe, Magne Geir

    2010-01-01

    a minimum of one predefined end point. In total, nine studies were identified. The 1,589 MOH patients (22% men) had an overall mean frequency of 25.3 headache days/month at baseline. Headache days/month at the end of follow-up was reported in six studies (mean 13.8 days/month). The decrease was more...... pronounced for studies including patients with migraine only (-14.6 days/month) compared to studies with the original diagnoses of migraine and tension-type headache (-9.2 days/month). Six studies reported relapse rate (mean of 26%) and/or responder rate (mean of 28%). Medication days/month and change...... in headache index at the end of follow-up were reported in only one and two of nine studies, respectively. The present review demonstrated a lack of uniform end points used in recently published follow-up studies. Guidelines for presenting follow-up data on MOH are needed and we propose end points...

  9. Bulk and interfacial molecular structure near liquid-liquid critical points

    Energy Technology Data Exchange (ETDEWEB)

    Manzanares-Papayanopoulos, Emilio

    2000-09-01

    Critical behaviour occurs when two coexisting phases merge identity without abrupt change in physical properties. The detail of this behaviour is nowadays considered universal, being dominated by the divergence of the correlation length {xi}. Following this universality, the detailed behaviour can be studied experimentally using any convenient system. For that reason, the study of fluids, and in particular fluid mixtures, offers a useful platform since critical behaviour in such systems can often be studied at convenient temperatures and pressures. Although criticality is a consequence of the divergence of {xi}, and so in a sense is a large-scale phenomenon, nevertheless it has an influence on events at molecular level. This aspect of criticality has received relatively little study compared to the enormous effort expended over the past thirty years in elucidating the macroscopic or phenomenological aspects of criticality. The signature of criticality at molecular level is the central theme running through this research.The aim of the work described in this thesis was to investigate the surface and transport properties of near-critical binary liquid mixtures. The surface properties mainly concerned the adsorption and wetting behaviour at the vapour-liquid and liquid-solid interfaces. The transport property studied was the shear viscosity at bulk or macroscopic level and the corresponding property at molecular or microscopic level, the micro viscosity. The work presented in this thesis comprises the experimental measurements and the theoretical interpretations drawn from the results. The experimental work was varied, using both classical and modern techniques. The theoretical interpretation was used as directed towards validating and comparing the results of the experimental programme with the predictions of the current classical critical-state theories. The systems investigated have been mostly alkane + perfluoroalkane mixtures or mixtures with very similar

  10. A coexistence curve equation for refrigerant-F-113 within the vicinity of the critical point

    International Nuclear Information System (INIS)

    Al'okhyin, O.D.; Bezruchko, Yi.V.; Bulavyin, L.A.

    2003-01-01

    The experimental data on the dependence of the density on temperature have been presented for refrigerant F-113 along the coexistence curve within the wide temperature range including the close vicinity of the critical temperature. The extended equation of state for freon-113 along this direction has been proposed on the base of the van der Waals model of a fluctuation gas. Parameters of the equation is determined by the interaction of molecules inside density fluctuations at the distances r>R c and by the interaction between fluctuations at the distances r>R c (R c is the correlation radius of the system)

  11. Rounding by disorder of first-order quantum phase transitions: emergence of quantum critical points.

    Science.gov (United States)

    Goswami, Pallab; Schwab, David; Chakravarty, Sudip

    2008-01-11

    We give a heuristic argument for disorder rounding of a first-order quantum phase transition into a continuous phase transition. From both weak and strong disorder analysis of the N-color quantum Ashkin-Teller model in one spatial dimension, we find that, for N > or =3, the first-order transition is rounded to a continuous transition and the physical picture is the same as the random transverse field Ising model for a limited parameter regime. The results are strikingly different from the corresponding classical problem in two dimensions where the fate of the renormalization group flows is a fixed point corresponding to N-decoupled pure Ising models.

  12. Socrates, Problem-based Learning and Critical Thinking—A Philosophic Point of View

    Directory of Open Access Journals (Sweden)

    Shin-Yun Wang

    2008-03-01

    Full Text Available Problem-based learning (PBL is a learner-centered educational method based on the principles of heuristics and collaboration. It has been considered an effective learning method in general and in professional education, especially in medical education. This article analyzes the thinking structure and philosophical background of PBL through the educational ideas of Socrates and the truth conception of Karl Popper. In the different phases of the PBL process, various truth conceptions will help to formulate the thinking framework of PBL—from Socrates' truth of openness toward the truth of scientific accuracy of our modern age. Meanwhile, Popper's scientific theory of falsifiability further leads us to discuss the relationship between PBL and critical thinking.

  13. Laser ablation of metal into liquid: near critical point phenomena and hydrodynamic instability

    Science.gov (United States)

    Inogamov, Nail; Zhakhovsky, Vasily; Khokhlov, Viktor

    2017-06-01

    Laser ablation of metal in contact with liquid differs much from ablation into vacuum. In spite of importance of this kind of laser-matter interaction (e.g., for nanoparticles production), the involved processes are still poorly understood. We show that to produce nanoparticles the laser absorbed energy should overcome the ablation threshold into vacuum by a few times. Thus the required temperatures in the heat-affected zone increase above a critical temperature. The flow of the substances, including propagation of a strong shock in liquid and a rarefaction wave inside the metal target, is analyzed. We demonstrate that the contact between metal and liquid, both being in their supercritical states, is hydrodynamically unstable. The instability is of the Rayleigh-Taylor type. Dynamics of the instability is important for separation of melt droplets which are frozen up to solid nanoparticles later.

  14. Spin- (1)/(2) Heisenberg ladder: Variation of entanglement and fidelity measures close to quantum critical points

    Science.gov (United States)

    Tribedi, Amit; Bose, Indrani

    2009-01-01

    We consider a two-chain, spin- (1)/(2) antiferromagnetic Heisenberg spin ladder in an external magnetic field H . The spin ladder is known to undergo second-order quantum phase transitions (QPTs) at two critical values Hc1 and Hc2 of the magnetic field. There are now known examples of strongly coupled (where the rung exchange interaction is much stronger than the nearest-neighbor intrachain exchange interaction) organic ladder compounds in which QPTs have been experimentally observed. In this paper, we investigate whether well-known bipartite entanglement meaures such as one-site von Neumann entropy, two-site von Neumann entropy, and concurrence develop special features close to the quantum critical points. As suggested by an earlier theorem, the first derivatives of the measures with respect to magnetic field are expected to diverge as H→Hc1 and H→Hc2 . Based on numerical diagonalization data and a mapping of the strongly coupled ladder Hamiltonian onto the XXZ chain Hamiltonian, for which several analytical results are known, we find that the derivatives of the entanglement measures diverge as H→Hc2 but remain finite as H→Hc1 . The reason for this discrepancy is analyzed. We further calculate two recently proposed quantum information theoretic measures, the reduced fidelity and reduced fidelity susceptibility, and show that these measures provide appropriate signatures of the QPTs occuring at the critical points H=Hc1 and H=Hc2 .

  15. Critical points and magnitude of impacts on the packing line: effect on ripening and quality of 'Packham's Triumph' pears

    Directory of Open Access Journals (Sweden)

    Josiane Pasini

    2017-06-01

    Full Text Available Pears have a very sensitive epidermis and are prone to signal mechanical blemishes, which result in reduced visual quality and low consumer acceptance. The objective of this work was to identify critical points and the magnitude of impact forces on a packing line at a commercial packinghouse. The effect of injuries on ripening and quality of ´Packham´s Triumph´ pears was also evaluated after cold storage. The packing line was scrutinized on its transfer points, fruit drop heights and cushioning overlays, which allowed to acquire the maximum accelerations on each spot. The maximum acceleration forces were reproduced in the lab with ‘Packham’s Triumph’ pears to evaluate the effects on fruit quality after cold storage. Four critical points were noticed on the packing line: at the transfer from the conveyor belt to the lifting rollers, at the transfer from the lifting rollers to the washing ramp with rotatory brushes, at the entrance to the singulator at the end of the conveyor belt and at the drop from the sizer to the packing stalls. Ripening of ‘Packham’s Triumph’ pears invariably came about during cold storage, and independently of the imposed impacts. The impacts under the circumstances of the test did not affect the quality of ´Packham´s Triumph´ pears kept for up to 120 days at cold storage followed by five days at room temperature.

  16. Harnack's Inequality for Degenerate and Singular Parabolic Equations

    CERN Document Server

    DiBenedetto, Emmanuele; Vespri, Vincenzo

    2012-01-01

    Degenerate and singular parabolic equations have been the subject of extensive research for the last 25 years. Despite important achievements, the issue of the Harnack inequality for non-negative solutions to these equations, both of p-Laplacian and porous medium type, while raised by several authors, has remained basically open. Recently considerable progress has been made on this issue, to the point that, except for the singular sub-critical range, both for the p-laplacian and the porous medium equations, the theory is reasonably complete. It seemed therefore timely to trace a comprehensive

  17. Numerical estimation of wall friction ratio near the pseudo-critical point with CFD-models

    International Nuclear Information System (INIS)

    Angelucci, M.; Ambrosini, W.; Forgione, N.

    2013-01-01

    In this paper, the STAR-CCM+ CFD code is used in the attempt to reproduce the values of friction factor observed in experimental data at supercritical pressures at various operating conditions. A short survey of available data and correlations for smooth pipe friction in circular pipes puts the basis for the discussion, reporting observed trends of friction factor in the liquid-like and the gas-like regions and within the transitional region across the pseudo-critical temperature. For smooth pipes, a general decrease of the friction factor in the transitional region is reported, constituting one of the relevant effects to be predicted by the computational fluid-dynamic models. A limited number of low-Reynolds number models are adopted, making use of refined near-wall discretisation as required by the constraint y + < 1 at the wall. In particular, the Lien k–ε and the SST k–ω models are considered. The values of the wall shear stress calculated by the code are then post-processed on the basis of bulk fluid properties to obtain the Fanning and then the Darcy–Weisbach friction factors, based on their classical definitions. The obtained values are compared with those provided by experimental tests and correlations, finding a reasonable qualitative agreement. Expectedly, the agreement is better in the gas-like and liquid-like regions, where fluid property changes are moderate, than in the transitional region, where the trends provided by available correlations are reproduced only in a qualitative way

  18. Simulating the phosphorus fluid-liquid phase transition up to the critical point

    International Nuclear Information System (INIS)

    Ghiringhelli, Luca M; Meijer, Evert Jan

    2007-01-01

    We report a Car-Parrinello molecular dynamics study of the temperature dependence of the fluid-liquid phase transition in phosphorous, involving the transformation of a molecular fluid phase into a network-like phase. We employed density-functional theory (DFT) with a gradient-corrected functional (B-LYP) to describe the electronic structure and interatomic interactions and performed simulations in a constant pressure ensemble. We spanned a temperature interval ranging from 2500 to 3500 K. With increasing temperature, we found that the structural conversion from the molecular P 4 fluid into the network liquid occurs at decreasing pressures, consistent with experimental observations. At lower temperatures the transition is characterized by a sudden increase of density in the sample. The magnitude of the density change decreases with increasing temperature and vanishes at 3500 K. In the temperature range 3100-3500 K we found signals of near- and super-criticality. We identified local structural changes that serve as seeds triggering the overall structural transition

  19. Evaluation of myofascial trigger points using infrared thermography: a critical review of the literature.

    Science.gov (United States)

    Dibai-Filho, Almir Vieira; Guirro, Rinaldo Roberto de Jesus

    2015-01-01

    The aim of this study was to review recent studies published on the use of infrared thermography for the assessment of myofascial trigger points (MTrPs). A search of the MEDLINE, CINAHL, PEDro, and SciELO databases was carried out between November 2012 and January 2013 for articles published in English, Portuguese, or Spanish from the year 2000 to 2012. Because of the nature of the included studies and the purpose of this review, the analysis of methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. The search retrieved 11 articles, 2 of which were excluded based on language (German and Chinese). Three were duplicated in different databases, 1 did not use infrared thermography for diagnostic purposes, and the other did not use infrared thermography to measure the skin temperature. Thus, the final sample was made up of 4 observational investigations: 3 comparative studies and 1 accuracy study. At present, there are few studies evaluating the accuracy and reliability of infrared thermography for the diagnosis and assessment of MTrPs. Of the few studies present, there is no agreement on skin temperature patterns in the presence of MTrPs. Copyright © 2015 National University of Health Sciences. Published by Elsevier Inc. All rights reserved.

  20. A simple model for the earthquake cycle combining self-organized complexity with critical point behavior

    Directory of Open Access Journals (Sweden)

    W. I. Newman

    2002-01-01

    Full Text Available We have studied a hybrid model combining the forest-fire model with the site-percolation model in order to better understand the earthquake cycle. We consider a square array of sites. At each time step, a "tree" is dropped on a randomly chosen site and is planted if the site is unoccupied. When a cluster of "trees" spans the site (a percolating cluster, all the trees in the cluster are removed ("burned" in a "fire." The removal of the cluster is analogous to a characteristic earthquake and planting "trees" is analogous to increasing the regional stress. The clusters are analogous to the metastable regions of a fault over which an earthquake rupture can propagate once triggered. We find that the frequency-area statistics of the metastable regions are power-law with a negative exponent of two (as in the forest-fire model. This is analogous to the Gutenberg-Richter distribution of seismicity. This "self-organized critical behavior" can be explained in terms of an inverse cascade of clusters. Small clusters of "trees" coalesce to form larger clusters. Individual trees move from small to larger clusters until they are destroyed. This inverse cascade of clusters is self-similar and the power-law distribution of cluster sizes has been shown to have an exponent of two. We have quantified the forecasting of the spanning fires using error diagrams. The assumption that "fires" (earthquakes are quasi-periodic has moderate predictability. The density of trees gives an improved degree of predictability, while the size of the largest cluster of trees provides a substantial improvement in forecasting a "fire."

  1. The Hazard Analysis and Critical Control Points (HACCP) generic model for the production of Thai fermented pork sausage (Nham).

    Science.gov (United States)

    Paukatong, K V; Kunawasen, S

    2001-01-01

    Nham is a traditional Thai fermented pork sausage. The major ingredients of Nham are ground pork meat and shredded pork rind. Nham has been reported to be contaminated with Salmonella spp., Staphylococcus aureus, and Listeria monocytogenes. Therefore, it is a potential cause of foodborne diseases for consumers. A Hazard Analysis and Critical Control Points (HACCP) generic model has been developed for the Nham process. Nham processing plants were observed and a generic flow diagram of Nham processes was constructed. Hazard analysis was then conducted. Other than microbial hazards, the pathogens previously found in Nham, sodium nitrite and metal were identified as chemical and physical hazards in this product, respectively. Four steps in the Nham process have been identified as critical control points. These steps are the weighing of the nitrite compound, stuffing, fermentation, and labeling. The chemical hazard of nitrite must be controlled during the weighing step. The critical limit of nitrite levels in the Nham mixture has been set at 100-200 ppm. This level is high enough to control Clostridium botulinum but does not cause chemical hazards to the consumer. The physical hazard from metal clips could be prevented by visual inspection of every Nham product during stuffing. The microbiological hazard in Nham could be reduced in the fermentation process. The critical limit of the pH of Nham was set at lower than 4.6. Since this product is not cooked during processing, finally, educating the consumer, by providing information on the label such as "safe if cooked before consumption", could be an alternative way to prevent the microbiological hazards of this product.

  2. Locating critical points on multi-dimensional surfaces by genetic algorithm: test cases including normal and perturbed argon clusters

    Science.gov (United States)

    Chaudhury, Pinaki; Bhattacharyya, S. P.

    1999-03-01

    It is demonstrated that Genetic Algorithm in a floating point realisation can be a viable tool for locating critical points on a multi-dimensional potential energy surface (PES). For small clusters, the standard algorithm works well. For bigger ones, the search for global minimum becomes more efficient when used in conjunction with coordinate stretching, and partitioning of the strings into a core part and an outer part which are alternately optimized The method works with equal facility for locating minima, local as well as global, and saddle points (SP) of arbitrary orders. The search for minima requires computation of the gradient vector, but not the Hessian, while that for SP's requires the information of the gradient vector and the Hessian, the latter only at some specific points on the path. The method proposed is tested on (i) a model 2-d PES (ii) argon clusters (Ar 4-Ar 30) in which argon atoms interact via Lennard-Jones potential, (iii) Ar mX, m=12 clusters where X may be a neutral atom or a cation. We also explore if the method could also be used to construct what may be called a stochastic representation of the reaction path on a given PES with reference to conformational changes in Ar n clusters.

  3. Canard solutions near a degenerate turning point

    Science.gov (United States)

    Forget, T.

    2006-12-01

    We are interested in the study of canard solutions in a singularly perturbed real first order ODE of the form epsilonu' = Ψ(x, u, a, epsilon), where epsilon > 0 is a small parameter, and a in Script R is a control parameter. An existence result for such solutions is given, and the method used in the demonstration allow us to conjecture the existence of a generalized epsilon1/(p+1)-asymptotic expansion for those solutions.

  4. Canard solutions near a degenerate turning point

    Energy Technology Data Exchange (ETDEWEB)

    Forget, T [Laboratoire de Mathematiques et Applications Pole, Sciences et Technologies - Universite de La Rochelle, Avenue Michel Crepeau, 17042 La Rochelle (France)

    2006-12-01

    We are interested in the study of canard solutions in a singularly perturbed real first order ODE of the form {epsilon}u' = {psi}(x, u, a, {epsilon}), where {epsilon} > 0 is a small parameter, and a element of R is a control parameter. An existence result for such solutions is given, and the method used in the demonstration allow us to conjecture the existence of a generalized {epsilon}{sup 1/(p+1)}-asymptotic expansion for those solutions.

  5. Multiple critical points and liquid-liquid equilibria from the van der Waals like equations of state

    International Nuclear Information System (INIS)

    Artemenko, Sergey; Lozovsky, Taras; Mazur, Victor

    2008-01-01

    The principal aim of this work is a comprehensive analysis of the phase diagram of water via the van der Waals like equations of state (EoSs) which are considered as superpositions of repulsive and attractive forces. We test more extensively the modified van der Waals EoS (MVDW) proposed by Skibinski et al (2004 Phys. Rev. E 69 061206) and refine this model by introducing instead of the classical van der Waals repulsive term a very accurate hard sphere EoS over the entire stable and metastable regions (Liu 2006 Preprint cond-mat/0605392). It was detected that the simplest form of MVDW EoS displays a complex phase behavior, including three critical points, and identifies four fluid phases (gas, low density liquid (LDL), high density liquid (HDL), and very high density liquid (VHDL)). Moreover the experimentally observed (Mallamace et al 2007 Proc. Natl Acad. Sci. USA 104 18387) anomalous behavior of the density of water in the deeply supercooled region (a density minimum) is reproduced by the MWDW EoS. An improvement of the repulsive part does not change the topological picture of the phase behavior of water in the wide range of thermodynamic variables. The new parameters set for second and third critical points are recognized by thorough analysis of experimental data for the loci of thermodynamic response function extrema

  6. Multiple critical points and liquid-liquid equilibria from the van der Waals like equations of state

    Energy Technology Data Exchange (ETDEWEB)

    Artemenko, Sergey; Lozovsky, Taras; Mazur, Victor [Thermodynamics Department, Academy of Refrigeration, 65082 Odessa (Ukraine)

    2008-06-18

    The principal aim of this work is a comprehensive analysis of the phase diagram of water via the van der Waals like equations of state (EoSs) which are considered as superpositions of repulsive and attractive forces. We test more extensively the modified van der Waals EoS (MVDW) proposed by Skibinski et al (2004 Phys. Rev. E 69 061206) and refine this model by introducing instead of the classical van der Waals repulsive term a very accurate hard sphere EoS over the entire stable and metastable regions (Liu 2006 Preprint cond-mat/0605392). It was detected that the simplest form of MVDW EoS displays a complex phase behavior, including three critical points, and identifies four fluid phases (gas, low density liquid (LDL), high density liquid (HDL), and very high density liquid (VHDL)). Moreover the experimentally observed (Mallamace et al 2007 Proc. Natl Acad. Sci. USA 104 18387) anomalous behavior of the density of water in the deeply supercooled region (a density minimum) is reproduced by the MWDW EoS. An improvement of the repulsive part does not change the topological picture of the phase behavior of water in the wide range of thermodynamic variables. The new parameters set for second and third critical points are recognized by thorough analysis of experimental data for the loci of thermodynamic response function extrema.

  7. Application of Hazard Analysis and Critical Control Points (HACCP) to the Cultivation Line of Mushroom and Other Cultivated Edible Fungi.

    Science.gov (United States)

    Pardo, José E; de Figueirêdo, Vinícius Reis; Alvarez-Ortí, Manuel; Zied, Diego C; Peñaranda, Jesús A; Dias, Eustáquio Souza; Pardo-Giménez, Arturo

    2013-09-01

    The Hazard analysis and critical control points (HACCP) is a preventive system which seeks to ensure food safety and security. It allows product protection and correction of errors, improves the costs derived from quality defects and reduces the final overcontrol. In this paper, the system is applied to the line of cultivation of mushrooms and other edible cultivated fungi. From all stages of the process, only the reception of covering materials (stage 1) and compost (stage 3), the pre-fruiting and induction (step 6) and the harvest (stage 7) have been considered as critical control point (CCP). The main hazards found were the presence of unauthorized phytosanitary products or above the permitted dose (stages 6 and 7), and the presence of pathogenic bacteria (stages 1 and 3) and/or heavy metals (stage 3). The implementation of this knowledge will allow the self-control of their productions based on the system HACCP to any plant dedicated to mushroom or other edible fungi cultivation.

  8. Use of the hazard analysis and critical control points (HACCP) risk assessment on a medical device for parenteral application.

    Science.gov (United States)

    Jahnke, Michael; Kühn, Klaus-Dieter

    2003-01-01

    In order to guarantee the consistently high quality of medical products for human use, it is absolutely necessary that flawless hygiene conditions are maintained by the strict observance of hygiene rules. With the growing understanding of the impact of process conditions on the quality of the resulting product, process controls (surveillance) have gained increasing importance to complete the quality profile traditionally defined by post-process product testing. Today, process controls have become an important GMP requirement for the pharmaceutical industry. However, before quality process controls can be introduced, the manufacturing process has to be analyzed, with the focus on its critical quality-influencing steps. The HACCP (Hazard Analysis and Critical Control Points) method is well recognized as a useful tool in the pharmaceutical industry. This risk analysis, following the guidelines of the HACCP method and the monitoring of critical steps during the manufacturing process was applied to the manufacture of methyl methacrylate solution used for bone cement and led to the establishment of a preventative monitoring system and constitutes an effective concept for quality assurance of hygiene and all other parameters influencing the quality of the product.

  9. Non-Fermi Liquid Behavior Close to a Quantum Critical Point in a Ferromagnetic State without Local Moments

    Directory of Open Access Journals (Sweden)

    E. Svanidze

    2015-03-01

    Full Text Available A quantum critical point (QCP occurs upon chemical doping of the weak itinerant ferromagnet Sc_{3.1}In. Remarkable for a system with no local moments, the QCP is accompanied by non-Fermi liquid behavior, manifested in the logarithmic divergence of the specific heat both in the ferro-and the paramagnetic states, as well as linear temperature dependence of the low-temperature resistivity. With doping, critical scaling is observed close to the QCP, as the critical exponents δ, γ, and β have weak composition dependence, with δ nearly twice and β almost half of their respective mean-field values. The unusually large paramagnetic moment μ_{PM}∼1.3μ_{B}/F.U. is nearly composition independent. Evidence for strong spin fluctuations, accompanying the QCP at x_{c}=0.035±0.005, may be ascribed to the reduced dimensionality of Sc_{3.1}In, associated with the nearly one-dimensional Sc-In chains.

  10. Predicting critical temperatures of ionic and non-ionic fluids from thermophysical data obtained near the melting point

    Science.gov (United States)

    Weiss, Volker C.

    2015-10-01

    In the correlation and prediction of thermophysical data of fluids based on a corresponding-states approach, the critical temperature Tc plays a central role. For some fluids, in particular ionic ones, however, the critical region is difficult or even impossible to access experimentally. For molten salts, Tc is on the order of 3000 K, which makes accurate measurements a challenging task. Room temperature ionic liquids (RTILs) decompose thermally between 400 K and 600 K due to their organic constituents; this range of temperatures is hundreds of degrees below recent estimates of their Tc. In both cases, reliable methods to deduce Tc based on extrapolations of experimental data recorded at much lower temperatures near the triple or melting points are needed and useful because the critical point influences the fluid's behavior in the entire liquid region. Here, we propose to employ the scaling approach leading to universal fluid behavior [Román et al., J. Chem. Phys. 123, 124512 (2005)] to derive a very simple expression that allows one to estimate Tc from the density of the liquid, the surface tension, or the enthalpy of vaporization measured in a very narrow range of low temperatures. We demonstrate the validity of the approach for simple and polar neutral fluids, for which Tc is known, and then use the methodology to obtain estimates of Tc for ionic fluids. When comparing these estimates to those reported in the literature, good agreement is found for RTILs, whereas the ones for the molten salts NaCl and KCl are lower than previous estimates by 10%. The coexistence curve for ionic fluids is found to be more adequately described by an effective exponent of βeff = 0.5 than by βeff = 0.33.

  11. [Epidemiologic aspects of a new approach to monitoring hygienic food handling using the hazard analysis critical control points (HACCP) system].

    Science.gov (United States)

    Matyás, Z

    1992-10-01

    The hitherto used traditional control of food hygiene focused on assessment whether the controlled sanitary and technological practice is consistent with requirements of regulations sometimes comprises also details of minor importance. To put it briefly, in the course of the production process are many check-up points, but only some or possibly only one is a critical control point. Moreover, by periodic supervision the hygienist is able to record the hygienic and technological state typical only for the time of control. Microbiological examination of final products can reveal only negative sequelae of microbial processes; it does not provide information on the conditions of contamination nor ensure protection against it. For these and other reasons the conclusion is reached that the hitherto used traditional approach of the hygiene supervision is not quite effective and must be replaced by a more active approach focused on the control of factors threatening the wholesomeness already during the production process. The new approach to supervision of food hygiene is the HACCP system (hazard analysis critical control points). The system works rationally as it is based on analysis of systematically assembled data on the causes and conditions which evoked the illness of the consumers by food products or meals. HACCP can be described as prompt, as health or quality problems are revealed immediately after their genesis during production or processing and are eliminated immediately. The system is also comprehensive as it comprises not only the basic technological process incl. processing or modification of ingredients but takes into account also the handling of the given food product after termination of production and in particular final culinar processing. The system can be applied to all pathogenic agents transmitted by foods to man from bacteria and their toxins, viruses, parasites, moulds and mycotoxins, biotoxins but also contaminants and radionuclides. The system

  12. Degenerate Euler zeta function

    OpenAIRE

    Kim, Taekyun

    2015-01-01

    Recently, T. Kim considered Euler zeta function which interpolates Euler polynomials at negative integer (see [3]). In this paper, we study degenerate Euler zeta function which is holomorphic function on complex s-plane associated with degenerate Euler polynomials at negative integers.

  13. Can the Hazard Assessment and Critical Control Points (HACCP) system be used to design process-based hygiene concepts?

    Science.gov (United States)

    Hübner, N-O; Fleßa, S; Haak, J; Wilke, F; Hübner, C; Dahms, C; Hoffmann, W; Kramer, A

    2011-01-01

    Recently, the HACCP (Hazard Analysis and Critical Control Points) concept was proposed as possible way to implement process-based hygiene concepts in clinical practice, but the extent to which this food safety concept can be transferred into the health care setting is unclear. We therefore discuss possible ways for a translation of the principles of the HACCP for health care settings. While a direct implementation of food processing concepts into health care is not very likely to be feasible and will probably not readily yield the intended results, the underlying principles of process-orientation, in-process safety control and hazard analysis based counter measures are transferable to clinical settings. In model projects the proposed concepts should be implemented, monitored, and evaluated under real world conditions.

  14. Post-operative endophthalmitis: the application of hazard analysis critical control points (HACCP) to an infection control problem.

    Science.gov (United States)

    Baird, D R; Henry, M; Liddell, K G; Mitchell, C M; Sneddon, J G

    2001-09-01

    Hazard analysis critical control points (HACCP) is a quality assurance system widely used in the food industry to ensure safety. We adopted the HACCP approach when conventional infection control measures had failed to solve an ongoing problem with an increased incidence of postoperative endophthalmitis, and our ophthalmology unit was threatened with permanent cessation of intraocular surgery. Although time-consuming, the result was an entirely new set of protocols for the care of patients undergoing intraocular surgery, the development of an integrated care pathway, and a comprehensive and robust audit programme, which enabled intraocular surgery to continue in a new spirit of confidence. HACCP methodology has so far been little used in healthcare, but it might be usefully applied to a variety of apparently intractable infection control problems. Copyright 2001 The Hospital Infection Society.

  15. Characterizing agosticity using the quantum theory of atoms in molecules: bond critical points and their local properties.

    Science.gov (United States)

    Tognetti, Vincent; Joubert, Laurent; Raucoules, Roman; De Bruin, Theodorus; Adamo, Carlo

    2012-06-07

    In this paper, we extend the work of Popelier and Logothetis [J. Organomet. Chem. 1998, 555, 101] on the characterization of agosticity by considerably enlarging the set of the studied organometallic molecules. To this aim, 23 representative complexes have been considered, including all first line transition metals at various oxidation states and exhibiting four types of agosticity (α, β, γ, and δ). From these examples, the concepts of agostic atom, agostic bond, and agostic interaction are defined and discussed, notably by advocating Bader's analysis of the electron density. The nature and the local properties of the bond critical points are then investigated, and the relationships with the main geometric parameters of the complexes are particularly examined. Moreover, new local descriptors based on kinetic energy densities are developed in order to provide new tools for bond characterization.

  16. Logarithmic terms in entanglement entropies of 2D quantum critical points and Shannon entropies of spin chains.

    Science.gov (United States)

    Zaletel, Michael P; Bardarson, Jens H; Moore, Joel E

    2011-07-08

    Universal logarithmic terms in the entanglement entropy appear at quantum critical points (QCPs) in one dimension (1D) and have been predicted in 2D at QCPs described by 2D conformal field theories. The entanglement entropy in a strip geometry at such QCPs can be obtained via the "Shannon entropy" of a 1D spin chain with open boundary conditions. The Shannon entropy of the XXZ chain is found to have a logarithmic term that implies, for the QCP of the square-lattice quantum dimer model, a logarithm with universal coefficient ±0.25. However, the logarithm in the Shannon entropy of the transverse-field Ising model, which corresponds to entanglement in the 2D Ising conformal QCP, is found to have a singular dependence on the replica or Rényi index resulting from flows to different boundary conditions at the entanglement cut.

  17. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: CARS spectroscopy of carbon dioxide in the critical point vicinity

    Science.gov (United States)

    Arakcheev, V. G.; Bagratashvili, Viktor N.; Valeev, A. A.; Gordienko, Vyacheslav M.; Kireev, Vyacheslav V.; Morozov, V. B.; Olenin, A. N.; Popov, Vladimir K.; Tunkin, V. G.; Yakovlev, D. V.

    2004-01-01

    The transformation of the Q-band of the low-frequency 1285-cm-1 component of the 2v2/v1 Fermi doublet of a CO2 molecule is studied in the critical point vicinity (Tc=31.03 °C, Pc=72.8 atm) by the CARS method. CARS spectra were recorded by changing pressure isothermically from 48 to 120 atm at several temperatures in the range between 25 and 36°C. At the temperature above 29°C, the pressure dependences of the Q-band width pass through the maximum, which exceeds by 40% —50% the typical Q-band width in the liquid phase. The position of the maximum shifts to higher pressures with increasing temperature. The inhomogeneous broadening of the Q-band is interpreted based on the cluster microstructure of a supercritical fluid.

  18. THz spectroscopy of one-dimensional Ising chain compound CoNb2O6 near the quantum critical point

    Science.gov (United States)

    Viirok, Johan; Hüvonen, D.; Rõõm, T.; Nagel, U.; Morris, C. M.; Koohpayeh, S. M.; McQueen, T. M.; Armitage, N. P.; Krizan, J.; Cava, R. J.

    One-dimensional Ising spin chain is a novel example of an interacting quantum many body system. The Ising chain in a transverse field is a good candidate to study quantum phase transitions because its low dimensionality increases its tendency to exhibit interesting quantum effects. We studied the one-dimensional ferromagnetic Ising chain material CoNb2O6 using far infrared spectroscopy in high magnetic fields up to 17 T and down to 0.3 K using a dilution refrigerator. Special attention is paid to the spectral region near the quantum critical point near 5.5 T. Research sponsored by the Estonian Ministry of Education and Research (IUT23-3) and Estonian Ministry of Education and Research and the European Regional Development Fund project TK134.

  19. LaCu6−xAgx : A promising host of an elastic quantum critical point

    Energy Technology Data Exchange (ETDEWEB)

    Poudel, Lekh [ORNL; Dela Cruz, Clarina R. [ORNL; Koehler, Michael R. [University of Tennessee, Knoxville (UTK); McGuire, Michael A. [ORNL; Keppens, Veerle [University of Tennessee, Knoxville (UTK); Mandrus, David [ORNL; Christianson, Andrew D. [ORNL

    2018-05-01

    Structural properties of LaCu6−xAgx have been investigated using neutron and x-ray diffraction, and resonant ultrasound spectroscopy (RUS) measurements. Diffraction measurements indicate a continuous structural transition from orthorhombic (Pnma) to monoclinic (P2₁/C) structure. RUS measurements show softening of natural frequencies at the structural transition, consistent with the elastic nature of the structural ground state. The structural transition temperatures in LaCu6−xAgx decrease with Ag composition until the monoclinic phase is completely suppressed at xc=0.225. All of the evidence is consistent with the presence of an elastic quantum critical point in LaCu6−xAgx.

  20. Onset of deconfinement and search for the critical point of strongly interacting matter at CERN SPS energies

    CERN Document Server

    Rybczynski, Maciej; Baatar, B.; Barna, D.; Bartke, J.; Beck, H.; Betev, L.; Bialkowska, H.; Blume, C.; Bogusz, M.; Boimska, B.; Book, J.; Botje, M.; Buncic, P.; Cetner, T.; Christakoglou, P.; Chung, P.; Chvala, O.; Cramer, J.G.; Eckardt, V.; Fodor, Z.; Foka, P.; Friese, V.; Gazdzicki, M.; Grebieszkow, K.; Hohne, C.; Kadija, K.; Karev, A.; Kolesnikov, V.I.; Kowalski, M.; Kresan, D.; Laszlo, A.; Lacey, R.; van Leeuwen, M.; Mackowiak-Pawlowska, M.; Makariev, M.; Malakhov, A.I.; Mateev, M.; Melkumov, G.L.; Mitrovski, M.; Mrowczynski, St.; Nicolic, V.; Palla, G.; Panagiotou, A.D.; Peryt, W.; Pluta, J.; Prindle, D.; Puhlhofer, F.; Renfordt, R.; Roland, C.; Roland, G.; Rybczynski, M.; Rybicki, A.; Sandoval, A.; Schmitz, N.; Schuster, T.; Seyboth, P.; Sikler, F.; Skrzypczak, E.; Slodkowski, M.; Stefanek, G.; Stock, R.; Strobele, H.; Susa, T.; Szuba, M.; Utvic, M.; Varga, D.; Vassiliou, M.; Veres, G.I.; Vesztergombi, G.; Vranic, D.; Wlodarczyk, Z.; Wojtaszek-Szwarc, A.

    2013-01-01

    The exploration of the QCD phase diagram particularly the search for a phase transition from hadronic to partonic degrees of freedom and possibly a critical endpoint, is one of the most challenging tasks in present heavy-ion physics. As observed by the NA49 experiment, several hadronic observables in central Pb+Pb collisions at the CERN SPS show qualitative changes in their energy dependence. These features are not observed in elementary interactions and indicate the onset of a phase transition in the SPS energy range. The existence of a critical point is expected to result in the increase of event-by-event fluctuations of various hadronic observables provided that the freeze-out of the measured hadrons occurs close to its location in the phase diagram and the evolution of the final hadron phase does not erase the fluctuations signals. A selection of NA49 results on di-pion and proton intermittency from the scan of the phase diagram will be discussed.

  1. Onset of deconfinement and search for the critical point of strongly interacting matter at CERN SPS energies

    CERN Document Server

    Rybczyński, Maciej

    2014-01-01

    The exploration of the QCD phase diagram particularly the search for a phase transition from hadronic to partonic degrees of freedom and possibly a critical endpoint, is one of the most challenging tasks in present heavy-ion physics. As observed by the NA49 experiment, several hadronic observables in central Pb+Pb collisions at the CERN SPS show qualitative changes in their energy dependence. These features are not observed in elementary interactions and indi- cate the onset of a phase transition in the SPS energy range. The existence of a critical point is expected to result in the increase of event-by-event fluctuations of various hadronic observables provided that the freeze-out of the measured hadrons occurs close to its location in the phase di- agram and the evolution of the final hadron phase does not erase the fluctuations signals. Further information about the existence and nature of a phase transition in the SPS energy range can be gained from the studies of event-by-event fluctuations of final stat...

  2. Present state of vapour pressure measurements up to 5000 K, and critical point data prediction of uranium oxide

    International Nuclear Information System (INIS)

    Ohse, R.W.; Babelot, J.F.; Cercignani, C.; Kinsman, P.R.; Long, K.A.; Magill, J.; Scotti, A.

    1979-01-01

    A new dynamic laser pulse heating technique, allowing thermophysical property measurement and equation of state studies above 3000 K is described. The vapour pressure measurements of uranium oxide up to 5000 K, as required for reactor safety analysis are presented. The present state of experimental work above the melting point is summarised. A complete survey on predicted critical point data of uranium oxides reviewing the various theoretical models is given. The various dynamic pulse heating techniques are outlined. For a study of the high temperature vapours and the gas dynamic expansion phenomena of the gas jet, the laser surface heating equipment has been extended to include high speed diagnostics such as multi-channel spectroscopy, time of flight mass spectrometry, and image converter photography in both the framing and streak recording mode. The evaporation process and thermodynamic interpretation of the data are discussed. A kinetic theory description of the laser induced vapour jet using a monoatomic gas dynamical model is given. The optical absorption in the gas jet, giving an upper temperature limit for the applicability of optical pyrometry has been calculated. The reduction of ionisation potential was found to be of minor importance. (Auth.)

  3. Hygienic-sanitary working practices and implementation of a Hazard Analysis and Critical Control Point (HACCP plan in lobster processing industries

    Directory of Open Access Journals (Sweden)

    Cristina Farias da Fonseca

    2013-03-01

    Full Text Available This study aimed to verify the hygienic-sanitary working practices and to create and implement a Hazard Analysis Critical Control Point (HACCP in two lobster processing industries in Pernambuco State, Brazil. The industries studied process frozen whole lobsters, frozen whole cooked lobsters, and frozen lobster tails for exportation. The application of the hygienic-sanitary checklist in the industries analyzed achieved conformity rates over 96% to the aspects evaluated. The use of the Hazard Analysis Critical Control Point (HACCP plan resulted in the detection of two critical control points (CCPs including the receiving and classification steps in the processing of frozen lobster and frozen lobster tails, and an additional critical control point (CCP was detected during the cooking step of processing of the whole frozen cooked lobster. The proper implementation of the Hazard Analysis Critical Control Point (HACCP plan in the lobster processing industries studied proved to be the safest and most cost-effective method to monitor each critical control point (CCP hazards.

  4. Degenerate Gauss hypergeometric functions

    OpenAIRE

    Vidunas, Raimundas

    2004-01-01

    This is a study of terminating and ill-defined Gauss hypergeometric functions. Corresponding hypergeometric equations have a degenerate set of of 24 Kummer's solutions. We describe those solutions and relations between them.

  5. Nature of the Blue-Phase-III endash isotropic critical point: An analogy with the liquid-gas transition

    International Nuclear Information System (INIS)

    Anisimov, M.A.; Agayan, V.A.; Collings, P.J.

    1998-01-01

    The analogy with the liquid-gas critical point is analyzed to clarify the nature of the pretransitional behavior of physical properties in the vicinity of the Blue-Phase-III endash isotropic transition in chiral liquid crystalline systems. The analogy is unusual: temperature serves as the ordering field and entropy plays the role of the order parameter. Both mean field and parametric equations of state are formulated in terms of scaling fields. The scaling fields are linear combinations of the physical fields, which are temperature and chirality. It is shown that mixing of the physical field variables naturally leads to a strong asymmetry with respect to the transition temperature in the behavior of the physical properties that cannot be described by simple power laws. While the mean field theory gives a good description of the experimental data, the scaling theory, if one incorporates mixing of the field variables, gives even better agreement with the experimental data, placing this transition in the same universality class as the three-dimensional Ising model. copyright 1998 The American Physical Society

  6. Metal food packaging design based on hazard analysis critical control point (HACCP system in canned food safety

    Directory of Open Access Journals (Sweden)

    Li Xingyi

    2016-06-01

    Full Text Available This study aims to design metal food packaging with hazard analysis critical control point (HACCP. First, theory of HACCP was introduced in detail. Taking empty cans provided by Wuxi Huapeng Food Packaging Company as an example, we studied migration of bisphenol compounds in coating of food can to food stimulant. Moreover, packaging design of luncheon meat can was taken as an example to confirm whether HACCP system could effectively control migration of phenolic substance. Results demonstrated that, coating of such empty were more likely to contain multiple bisphenol compounds such as bisphenol A (BPA, and bisphenol A diglycidyl ether (BADGE was considered as the leading bisphenol pollutant; food stimulant of different types, storage temperature and time could all impact migration of bisphenol compounds. HACCP system was proved to be effective in controlling hazards of phenolic substance in luncheon meat can and could reduce various phenolic substance indexes to an acceptable range. Therefore, HACCP can control migration of phenolic substance and recontamination of food and thus ensure food safety.

  7. dx^2-y^2 paring symmetry of heavy fermion CeIrIn5 remote from antiferromagnetic quantum critical point

    Science.gov (United States)

    Kasahara, Yuichi; Iwasawa, T.; Shimizu, Y.; Shishido, H.; Shibauchi, T.; Vekhter, I.; Matsuda, Y.

    2008-03-01

    Quasi-two dimensional heavy Fermion CeIrIn5 involves two distinct superconducting domes in the phase diagram, which appear as a function of pressure or Rh substitution of Ir. In the analogy to CeCu2Si2, two distinct superconducting domes with different symmetry has been invoked. We report on the results of low-temperature thermal transport of CeIrIn5 in the second dome, which locates away from an antiferromagnetic quantum critical point. The thermal conductivity is measured under a magnetic field rotated with respect to the crystal axes, which give direct evidence for superconducting gap structure. Clear fourfold oscillation with minima at [110] and [1-10] directions is observed as rotating magnetic field within the basal ab-plane, while no oscillation is observed within the bc-plane. In sharp contrast to previous reports that suggested Eg symmetry with horizontal line node within the ab-plane [1], our results are most consistent with dx^2- y^2 symmetry with vertical line nodes along the c-axis. These results imply that two superconducting domes have the same gap symmetry which appears to be mediated by antiferromagnetic spin fluctuations. [1] H. Shakeripour et al., Phys. Rev. Lett. 99, 187004 (2007).

  8. Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration

    OpenAIRE

    Ma, Hongwei; Thapa, Arjun; Morris, Lynsie; Redmond, T. Michael; Baehr, Wolfgang; Ding, Xi-Qin

    2014-01-01

    Photoreceptors degenerate in a wide array of hereditary retinal diseases and age-related macular degeneration. There is currently no treatment available for retinal degenerations. While outnumbered roughly 20:1 by rods in the human retina, it is the cones that mediate color vision and visual acuity, and their survival is critical for vision. In this communication, we investigate whether thyroid hormone (TH) signaling affects cone viability in retinal degeneration mouse models. TH signaling is...

  9. 4-Point ultrasonography to confirm the correct position of the nasogastric tube in 114 critically ill patients.

    Science.gov (United States)

    Zatelli, Marianna; Vezzali, Norberto

    2017-03-01

    Nasogastric feeding tube is routinely positioned in intensive care units. The complications of misplacement are rare but very dangerous for the patients. The aim of this study is to estimate the diagnostic accuracy of this new technique, 4-point ultrasonography to confirm nasogastric tube placement in intensive care. One hundred fourteen critical ill patients monitored in ICU were included. The intensivist provided in real time to perform the exam in four steps: sonography from either the right or left side of the patient's neck to visualize the esophagus, sonography of epigastrium to confirm the passage through the esophagogastric junction and the positioning in antrum, sonography of the fundus. Finally, gastric placement of the nasogastric feeding tube was confirmed with thorax radiograph. One hundred fourteen of the gastric tubes were visualized by sonography in the digestive tract and all were confirmed by radiography (sensitivity 100%). The entire sonographic procedure, including the longitudinal and transversal scan of the esophagus, the esophagogastric junction, the antrum and the fundus, took 10 min. Our pilot study demonstrated that not weighted-tip gastric tube routinely used in Intensive Care is visible with the sonography. The pilot study confirmed the high sensitivity of the sonography in the verify correct positioning of gastric tube in the adult ICU patients. The ultrasound examination seems to be easy and rapid even when performed by a intensivist whit a sonographic training of only 40 h. The sonographic exam at the bedside was performed in a shorter time than the acquisition and reporting of the X-ray.

  10. Evaluation of an active learning module to teach hazard and risk in Hazard Analysis and Critical Control Points (HACCP) classes.

    Science.gov (United States)

    Oyarzabal, Omar A; Rowe, Ellen

    2017-04-01

    The terms hazard and risk are significant building blocks for the organization of risk-based food safety plans. Unfortunately, these terms are not clear for some personnel working in food manufacturing facilities. In addition, there are few examples of active learning modules for teaching adult participants the principles of hazard analysis and critical control points (HACCP). In this study, we evaluated the effectiveness of an active learning module to teach hazard and risk to participants of HACCP classes provided by the University of Vermont Extension in 2015 and 2016. This interactive module is comprised of a questionnaire; group playing of a dice game that we have previously introduced in the teaching of HACCP; the discussion of the terms hazard and risk; and a self-assessment questionnaire to evaluate the teaching of hazard and risk. From 71 adult participants that completed this module, 40 participants (56%) provided the most appropriate definition of hazard, 19 participants (27%) provided the most appropriate definition of risk, 14 participants (20%) provided the most appropriate definitions of both hazard and risk, and 23 participants (32%) did not provide an appropriate definition for hazard or risk. Self-assessment data showed an improvement in the understanding of these terms (P < 0.05). Thirty participants (42%) stated that the most valuable thing they learned with this interactive module was the difference between hazard and risk, and 40 participants (65%) responded that they did not attend similar presentations in the past. The fact that less than one third of the participants answered properly to the definitions of hazard and risk at baseline is not surprising. However, these results highlight the need for the incorporation of modules to discuss these important food safety terms and include more active learning modules to teach food safety classes. This study suggests that active learning helps food personnel better understand important food safety

  11. Locating the QCD critical end point through peaked baryon number susceptibilities along the freeze-out line

    Science.gov (United States)

    Li, Zhibin; Chen, Yidian; Li, Danning; Huang, Mei

    2018-01-01

    We investigate the baryon number susceptibilities up to fourth order along different freeze-out lines in a holographic QCD model with a critical end point (CEP), and we propose that the peaked baryon number susceptibilities along the freeze-out line can be used as a clean signature to locate the CEP in the QCD phase diagram. On the temperature and baryon chemical potential plane, the cumulant ratio of the baryon number susceptibilities (up to fourth order) forms a ridge along the phase boundary, and develops a sword-shaped “mountain” standing upright around the CEP in a narrow and oblate region. The measurement of baryon number susceptibilities from heavy-ion collision experiments is along the freeze-out line. If the freeze-out line crosses the foot of the CEP mountain, then one can observe the peaked baryon number susceptibilities along the freeze-out line, and the kurtosis of the baryon number distributions has the highest magnitude. The data from the first phase of the beam energy scan program at the Relativistic Heavy Ion Collider indicates that there should be a peak of the kurtosis of the baryon number distribution at a collision energy of around 5 GeV, which suggests that the freeze-out line crosses the foot of the CEP mountain and the summit of the CEP should be located nearby, around a collision energy of 3–7 GeV. Supported by NSFC (11275213, and 11261130311) (CRC 110 by DFG and NSFC), CAS key project KJCX2-EW-N01, and Youth Innovation Promotion Association of CAS

  12. Application of hazard analysis and critical control point methodology and risk-based grading to consumer food safety surveys.

    Science.gov (United States)

    Røssvoll, Elin Halbach; Ueland, Øydis; Hagtvedt, Therese; Jacobsen, Eivind; Lavik, Randi; Langsrud, Solveig

    2012-09-01

    Traditionally, consumer food safety survey responses have been classified as either "right" or "wrong" and food handling practices that are associated with high risk of infection have been treated in the same way as practices with lower risks. In this study, a risk-based method for consumer food safety surveys has been developed, and HACCP (hazard analysis and critical control point) methodology was used for selecting relevant questions. We conducted a nationally representative Web-based survey (n = 2,008), and to fit the self-reported answers we adjusted a risk-based grading system originally developed for observational studies. The results of the survey were analyzed both with the traditional "right" and "wrong" classification and with the risk-based grading system. The results using the two methods were very different. Only 5 of the 10 most frequent food handling violations were among the 10 practices associated with the highest risk. These 10 practices dealt with different aspects of heat treatment (lacking or insufficient), whereas the majority of the most frequent violations involved storing food at room temperature for too long. Use of the risk-based grading system for survey responses gave a more realistic picture of risks associated with domestic food handling practices. The method highlighted important violations and minor errors, which are performed by most people and are not associated with significant risk. Surveys built on a HACCP-based approach with risk-based grading will contribute to a better understanding of domestic food handling practices and will be of great value for targeted information and educational activities.

  13. Laenderyggens degeneration og radiologi

    DEFF Research Database (Denmark)

    Jacobsen, Steffen; Gosvig, Kasper Kjaerulf; Sonne-Holm, Stig

    2006-01-01

    Low back pain (LBP) is one of the most common conditions, and at the same time one of the most complex nosological entities. The lifetime prevalence is approximately 80%, and radiological features of lumbar degeneration are almost universal in adults. The individual risk factors for LBP and signi...... is cyclic: exacerbations relieved by asymptomatic periods. New imaging modalities, including the combination of MR imaging and multiplanar 3-D CT scans, have broadened our awareness of possible pain-generating degenerative processes of the lumbar spine other than disc degeneration....

  14. Effects of equilibrium point displacement in limit cycle oscillation amplitude, critical frequency and prediction of critical input angular velocity in minimal brake system

    Science.gov (United States)

    Ganji, Hamed Faghanpour; Ganji, Davood Domiri

    2017-04-01

    In the present paper, brake squeal phenomenon as a noise resource in automobiles was studied. In most cases, the modeling work is carried out assuming that deformations were small; thus, equilibrium point is set zero and linearization is performed at this point. However, the equilibrium point under certain circumstances is not zero; therefore, huge errors in prediction of brake squeal may occur. In this work, large motion domains with respect to linearization importance were subjected to investigation. Nonlinear equations of motion were considered and behavior of system for COF's model was analyzed by studying amplitude and frequency of limited cycle oscillation.

  15. Point and trend accuracy of a continuous intravenous microdialysis-based glucose-monitoring device in critically ill patients: a prospective study

    NARCIS (Netherlands)

    Leopold, J. H.; van Hooijdonk, R. T. M.; Boshuizen, M.; Winters, T.; Bos, L. D.; Abu-Hanna, A.; Hoek, A. M. T.; Fischer, J. C.; van Dongen-Lases, E. C.; Schultz, M. J.

    2016-01-01

    Microdialysis is a well-established technology that can be used for continuous blood glucose monitoring. We determined point and trend accuracy, and reliability of a microdialysis-based continuous blood glucose-monitoring device (EIRUS(®)) in critically ill patients. Prospective study involving

  16. Universal Signatures of Quantum Critical Points from Finite-Size Torus Spectra: A Window into the Operator Content of Higher-Dimensional Conformal Field Theories.

    Science.gov (United States)

    Schuler, Michael; Whitsitt, Seth; Henry, Louis-Paul; Sachdev, Subir; Läuchli, Andreas M

    2016-11-18

    The low-energy spectra of many body systems on a torus, of finite size L, are well understood in magnetically ordered and gapped topological phases. However, the spectra at quantum critical points separating such phases are largely unexplored for (2+1)D systems. Using a combination of analytical and numerical techniques, we accurately calculate and analyze the low-energy torus spectrum at an Ising critical point which provides a universal fingerprint of the underlying quantum field theory, with the energy levels given by universal numbers times 1/L. We highlight the implications of a neighboring topological phase on the spectrum by studying the Ising* transition (i.e. the transition between a Z_{2} topological phase and a trivial paramagnet), in the example of the toric code in a longitudinal field, and advocate a phenomenological picture that provides qualitative insight into the operator content of the critical field theory.

  17. Identification of gram-negative bacteria from critical control points of raw and pasteurized cow milk consumed at Gondar town and its suburbs, Ethiopia.

    Science.gov (United States)

    Garedew, Legesse; Berhanu, Ayalew; Mengesha, Desalegne; Tsegay, Getachew

    2012-11-06

    Milk is highly prone to contamination and can serve as an efficient vehicle for human transmission of foodborne pathogens, especially gram-negative bacteria, as these are widely distributed in the environment. This cross-sectional study of gram-negative staining bacterial contamination of milk meant for human consumption was carried out from October 2010 to May 2011 in Gondar town, Ethiopia. Milk samples were collected from critical control points, from production to consumption, that were hypothesized to be a source of potential contamination. Milk sampling points included smallholder's milk producers, dairy co-operatives, a milk processing plant, and supermarkets. The hygienic procedures applied during milking, milk collection, transportation, pasteurization, and postpasteurization storage conditions at these specified critical control points were evaluated. Standard bacteriological cultivation and biochemical assays were used to isolate and identify bacterial pathogens in the milk samples. The results of the current study showed that conditions for contamination of raw milk at different critical points were due to less hygienic practices in pre-milking udder preparation, sub-optimal hygiene of milk handlers, and poor sanitation practices associated with milking and storage equipments. Among all critical control points considered, transportation containers at milk collection centers and at processing plants were found to be the most heavily contaminated with gram-negative staining bacterial species. Overall, 54 different bacterial species were indentified, and Escherichia coli (29.6%), Pseudomonas aeruginosa (18.5%), and Klebsiella pneumoniae (16.7%), were the most commonly identified gram-negative staining bacterial pathogens. Of particular interest was that no gram-negative staining bacteria were isolated from pasteurized milk samples with varying shelf life. This study showed the presence of diverse pathogenic gram-negative staining bacterial species in raw

  18. Identification of gram-negative bacteria from critical control points of raw and pasteurized cow milk consumed at Gondar town and its suburbs, Ethiopia

    Directory of Open Access Journals (Sweden)

    Garedew Legesse

    2012-11-01

    Full Text Available Abstract Background Milk is highly prone to contamination and can serve as an efficient vehicle for human transmission of foodborne pathogens, especially gram-negative bacteria, as these are widely distributed in the environment. Methods This cross-sectional study of gram-negative staining bacterial contamination of milk meant for human consumption was carried out from October 2010 to May 2011 in Gondar town, Ethiopia. Milk samples were collected from critical control points, from production to consumption, that were hypothesized to be a source of potential contamination. Milk sampling points included smallholder’s milk producers, dairy co-operatives, a milk processing plant, and supermarkets. The hygienic procedures applied during milking, milk collection, transportation, pasteurization, and postpasteurization storage conditions at these specified critical control points were evaluated. Standard bacteriological cultivation and biochemical assays were used to isolate and identify bacterial pathogens in the milk samples. Results The results of the current study showed that conditions for contamination of raw milk at different critical points were due to less hygienic practices in pre-milking udder preparation, sub-optimal hygiene of milk handlers, and poor sanitation practices associated with milking and storage equipments. Among all critical control points considered, transportation containers at milk collection centers and at processing plants were found to be the most heavily contaminated with gram-negative staining bacterial species. Overall, 54 different bacterial species were indentified, and Escherichia coli (29.6%, Pseudomonas aeruginosa (18.5%, and Klebsiella pneumoniae (16.7%, were the most commonly identified gram-negative staining bacterial pathogens. Of particular interest was that no gram-negative staining bacteria were isolated from pasteurized milk samples with varying shelf life. Conclusion This study showed the presence of

  19. Laenderyggens degeneration og radiologi

    DEFF Research Database (Denmark)

    Jacobsen, Steffen; Gosvig, Kasper Kjaerulf; Sonne-Holm, Stig

    2006-01-01

    Low back pain (LBP) is one of the most common conditions, and at the same time one of the most complex nosological entities. The lifetime prevalence is approximately 80%, and radiological features of lumbar degeneration are almost universal in adults. The individual risk factors for LBP and signi......Low back pain (LBP) is one of the most common conditions, and at the same time one of the most complex nosological entities. The lifetime prevalence is approximately 80%, and radiological features of lumbar degeneration are almost universal in adults. The individual risk factors for LBP...... and significant relationships between radiological findings and subjective symptoms have both been notoriously difficult to identify. The lack of consensus on clinical criteria and radiological definitions has hampered the undertaking of properly executed epidemiological studies. The natural history of LBP...

  20. Adjacent segment degeneration

    OpenAIRE

    Birjandi, Alireza

    2012-01-01

    Abstract: Adjacent segment disease (ASD) is defined as degeneration that develops at mobile segments above or below a fused spinal segment and usually develops after spinal fusion or other back surgeries. Nearly 5 decades ago, the medical findings related to ASD were usually released in case reports as a relatively unusual complication of lumbar or lumbosacral fusions. Since the initial reports, ASD has been found to occur more often than the earlier predictions for its prospect incidence. It...

  1. Critical points in magnetic systems, a neutron diffraction study of CsCoCl/sub 3/2D/sub 2/O

    Energy Technology Data Exchange (ETDEWEB)

    Bongaarts, A.L.M.

    1975-12-01

    A review is given of the present phenomenological theories of critical points in terms of the scaling -, the universality-, and the smoothness hypothesis. The experimental part describes an investigation by means of thermal neutron scattering to the magnetic phase transitions in the metamagnet CsCoCl/sub 3/.2D/sub 2/0, T/sub N/ = 3.30/sup 0/K. Along the line of critical points, that separates the antiferromagnetic region from the paramagnetic region in the HT-phase diagram, the critical behavior is found both qualitatively and quantitatively in agreement with the predictions of the smoothness hypothesis. A tricritical point is located at T/sub t/ = 1.85/sup 0/K and H/sub t/ = 2.70 k0e, and a full set of tricritical exponents is obtained. It is demonstrated that these exponents are in agreement with the predictions of the scaling hypothesis at a tricritical point, but differ from the classical exponents predicted by recent renormalization group techniques.

  2. A new model approach for the near-critical point region: 1. Construction of the generalized van der Waals equation of state.

    Science.gov (United States)

    Lee, Sukbae; Jeon, Joonhyeon; Kim, Wonsoo; Chair, Tong-Seek

    2008-12-11

    To date, it has been considered that all classical equations of state (EOS) have failed to describe the properties of fluids near the critical region, where the density fluctuations have a significant influence on fluid properties. In this paper, we suggest a newly constructed equation for fluid states, the generalized van der Waals (GvdW) EOS with the highly simplified Dieterici's form P = [RT/(V - b)] - a(b/V)c by a new model potential construction describing intermolecular interactions. On the basis of the model potential construction, it is shown that the a, b, and c parameters have physical interpretations as an internal pressure, a void volume, and a dimensionless value that represents an inharmonic intermolecular cell potential, respectively. As an illustration of our model approach, we initially apply it to near the critical point (cp) region, where all classical EOS descriptions have been incorporated with experimental thermodynamic data, and we obtain a table of three parameters for 12 pure normal fluids, which precisely describes thermodynamic critical values. On the basis of the basic relations between pressure and volume at the critical point, we express the corresponding EOS in terms of the c parameter, and by this means, we also obtain a theoretical vapor-liquid equilibrium (VLE) line, which closely coincides with the experimental data for several pure normal fluids near the critical region. As a result, we show that thermodynamic properties near the critical region can be described analytically by only three parameters. In addition, to validate our EOS for the temperature-differential derivatives, we show that the calculated isochoric heat capacity (Cv) of saturated argon closely coincides with the experimental data. Moreover, the possibility of a precise description with respect to the entire fluid region is also argued, in terms of the physical cases from the triple point to the ideal gas region.

  3. Effect of the quartic gradient terms on the critical exponents of the Wilson-Fisher fixed point in O(N) models

    Science.gov (United States)

    Péli, Zoltán; Nagy, Sándor; Sailer, Kornel

    2018-02-01

    The effect of the O(partial4) terms of the gradient expansion on the anomalous dimension η and the correlation length's critical exponent ν of the Wilson-Fisher fixed point has been determined for the Euclidean 3-dimensional O( N) models with N≥ 2 . Wetterich's effective average action renormalization group method is used with field-independent derivative couplings and Litim's optimized regulator. It is shown that the critical theory is well approximated by the effective average action preserving O( N) symmetry with an accuracy of O(η).

  4. From ‘Seeing’ to ‘Seizing’ Opportunity: Critical Events, Turning Points and Ethnolinguistic Mobilization in the Basque Country

    NARCIS (Netherlands)

    Heidemann, Kai

    2014-01-01

    This article examines how social movement actors carry out the transition from ‘seeing’ to ‘seizing’ critical events as empowering structures of political opportunity. Drawing on qualitative data, the discussion looks at how Basque language activists affiliated with the ikastola schooling movement

  5. Blow-Up Analysis for a Quasilinear Degenerate Parabolic Equation with Strongly Nonlinear Source

    Directory of Open Access Journals (Sweden)

    Pan Zheng

    2012-01-01

    Full Text Available We investigate the blow-up properties of the positive solution of the Cauchy problem for a quasilinear degenerate parabolic equation with strongly nonlinear source ut=div(|∇um|p−2∇ul+uq,  (x,t∈RN×(0,T, where N≥1, p>2 , and m, l,  q>1, and give a secondary critical exponent on the decay asymptotic behavior of an initial value at infinity for the existence and nonexistence of global solutions of the Cauchy problem. Moreover, under some suitable conditions we prove single-point blow-up for a large class of radial decreasing solutions.

  6. Degenerate RFID Channel Modeling for Positioning Applications

    Directory of Open Access Journals (Sweden)

    A. Povalac

    2012-12-01

    Full Text Available This paper introduces the theory of channel modeling for positioning applications in UHF RFID. It explains basic parameters for channel characterization from both the narrowband and wideband point of view. More details are given about ranging and direction finding. Finally, several positioning scenarios are analyzed with developed channel models. All the described models use a degenerate channel, i.e. combined signal propagation from the transmitter to the tag and from the tag to the receiver.

  7. Two- and three-point functions at criticality: Monte Carlo simulations of the improved three-dimensional Blume-Capel model

    Science.gov (United States)

    Hasenbusch, Martin

    2018-01-01

    We compute two- and three-point functions at criticality for the three-dimensional Ising universality class. To this end, we simulate the improved Blume-Capel model at the critical temperature on lattices of a linear size up to L =1600 . As a check, also simulations of the spin-1/2 Ising model are performed. We find fσ σ ɛ=1.051 (1 ) and fɛ ɛ ɛ=1.533 (5 ) for operator product expansion coefficients. These results are consistent with but less precise than those recently obtained by using the bootstrap method. An important ingredient in our simulations is a variance reduced estimator of N -point functions. Finite size corrections vanish with L-Δɛ, where L is the linear size of the lattice and Δɛ is the scaling dimension of the leading Z2-even scalar ɛ .

  8. [Experience with knowledge development in food handlers with te implementation of Hazard Analysis Critical control points (HACCP) in a hospital food service].

    Science.gov (United States)

    de Sousa, A A; de Salles, R K; Felipe, M R; Tosin, I

    1999-03-01

    The present article has as objective to describe the methodology of an experience of implantation of Hazard Analyses Critical Control Points (HACCP) with food handlers in a hospital food service establishment, inside of a conception of relationship and construction of knowledge. Meetings with the food handlers and nutritionists, with the objective of raising the difficulties poined for the sector and the work to be developed. The HACCP consisted of the evaluation of the operations, following the sequential steps recommended, looking itself to instruct the food handlers on the methods of the operations and its interpretations. The detected critical points, the measures of control, the criteria of correction and the monitoring have widely been argued, serving as didactic elements for the reconstruction of quality of the preparations. The discussions generated actions that were developed in short term, revealing the need of a more effective and continuous partnership for the new proposals.

  9. Spin-1/2 Heisenberg ladder: variation of entanglement and fidelity measures close to quantum critical points

    OpenAIRE

    Tribedi, Amit; Bose, Indrani

    2008-01-01

    We consider a two-chain, spin-1/2 antiferromagnetic Heisenberg spin ladder in an external magnetic field H. The spin ladder is known to undergo second order quantum phase transitions (QPTs) at two critical values, Hc1 and Hc2, of the magnetic field. There are now known examples of strongly coupled (rung exchange interaction much stronger than nearest-neighbour intrachain exchange interaction) organic ladder compounds in which QPTs have been experimentally observed. In this paper, we investiga...

  10. On the critical point of the fully-anisotropic quenched bond-random Potts ferromagnet in triangular and honeycomb lattices

    International Nuclear Information System (INIS)

    Tsallis, C.; Santos, R.J.V. dos

    1983-01-01

    On conjectural grounds an equation that provides a very good approximation for the critical temperature of the fully-anisotropic homogeneous quenched bond-random q-state Potts ferromagnet in triangular and honeycomb lattices is presented. Almost all the exact particular results presently known for the square, triangular and honeycomb lattices are recovered; the numerical discrepancy is quite small for the few exceptions. Some predictions that we believe to be exact are made explicite as well. (Author) [pt

  11. Phase space barriers and dividing surfaces in the absence of critical points of the potential energy: Application to roaming in ozone

    Energy Technology Data Exchange (ETDEWEB)

    Mauguière, Frédéric A. L., E-mail: frederic.mauguiere@bristol.ac.uk; Collins, Peter, E-mail: peter.collins@bristol.ac.uk; Wiggins, Stephen, E-mail: stephen.wiggins@mac.com [School of Mathematics, University of Bristol, Bristol BS8 1TW (United Kingdom); Kramer, Zeb C., E-mail: zebcolterkramer@gmail.com; Ezra, Gregory S., E-mail: gse1@cornell.edu [Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853 (United States); Carpenter, Barry K., E-mail: carpenterb1@cardiff.ac.uk [School of Chemistry, Cardiff University, Cardiff CF10 3AT (United Kingdom); Farantos, Stavros C., E-mail: farantos@iesl.forth.gr [Institute of Electronic Structure and Laser, Foundation for Research and Technology - Hellas, and Department of Chemistry, University of Crete, Iraklion 711 10, Crete (Greece)

    2016-02-07

    We examine the phase space structures that govern reaction dynamics in the absence of critical points on the potential energy surface. We show that in the vicinity of hyperbolic invariant tori, it is possible to define phase space dividing surfaces that are analogous to the dividing surfaces governing transition from reactants to products near a critical point of the potential energy surface. We investigate the problem of capture of an atom by a diatomic molecule and show that a normally hyperbolic invariant manifold exists at large atom-diatom distances, away from any critical points on the potential. This normally hyperbolic invariant manifold is the anchor for the construction of a dividing surface in phase space, which defines the outer or loose transition state governing capture dynamics. We present an algorithm for sampling an approximate capture dividing surface, and apply our methods to the recombination of the ozone molecule. We treat both 2 and 3 degrees of freedom models with zero total angular momentum. We have located the normally hyperbolic invariant manifold from which the orbiting (outer) transition state is constructed. This forms the basis for our analysis of trajectories for ozone in general, but with particular emphasis on the roaming trajectories.

  12. Laenderyggens degeneration og radiologi

    DEFF Research Database (Denmark)

    Jacobsen, Steffen; Gosvig, Kasper Kjaerulf; Sonne-Holm, Stig

    2006-01-01

    and significant relationships between radiological findings and subjective symptoms have both been notoriously difficult to identify. The lack of consensus on clinical criteria and radiological definitions has hampered the undertaking of properly executed epidemiological studies. The natural history of LBP......Low back pain (LBP) is one of the most common conditions, and at the same time one of the most complex nosological entities. The lifetime prevalence is approximately 80%, and radiological features of lumbar degeneration are almost universal in adults. The individual risk factors for LBP...

  13. Food safety and nutritional quality for the prevention of non communicable diseases: the Nutrient, hazard Analysis and Critical Control Point process (NACCP).

    Science.gov (United States)

    Di Renzo, Laura; Colica, Carmen; Carraro, Alberto; Cenci Goga, Beniamino; Marsella, Luigi Tonino; Botta, Roberto; Colombo, Maria Laura; Gratteri, Santo; Chang, Ting Fa Margherita; Droli, Maurizio; Sarlo, Francesca; De Lorenzo, Antonino

    2015-04-23

    The important role of food and nutrition in public health is being increasingly recognized as crucial for its potential impact on health-related quality of life and the economy, both at the societal and individual levels. The prevalence of non-communicable diseases calls for a reformulation of our view of food. The Hazard Analysis and Critical Control Point (HACCP) system, first implemented in the EU with the Directive 43/93/CEE, later replaced by Regulation CE 178/2002 and Regulation CE 852/2004, is the internationally agreed approach for food safety control. Our aim is to develop a new procedure for the assessment of the Nutrient, hazard Analysis and Critical Control Point (NACCP) process, for total quality management (TMQ), and optimize nutritional levels. NACCP was based on four general principles: i) guarantee of health maintenance; ii) evaluate and assure the nutritional quality of food and TMQ; iii) give correct information to the consumers; iv) ensure an ethical profit. There are three stages for the application of the NACCP process: 1) application of NACCP for quality principles; 2) application of NACCP for health principals; 3) implementation of the NACCP process. The actions are: 1) identification of nutritional markers, which must remain intact throughout the food supply chain; 2) identification of critical control points which must monitored in order to minimize the likelihood of a reduction in quality; 3) establishment of critical limits to maintain adequate levels of nutrient; 4) establishment, and implementation of effective monitoring procedures of critical control points; 5) establishment of corrective actions; 6) identification of metabolic biomarkers; 7) evaluation of the effects of food intake, through the application of specific clinical trials; 8) establishment of procedures for consumer information; 9) implementation of the Health claim Regulation EU 1924/2006; 10) starting a training program. We calculate the risk assessment as follows

  14. Inflammation in intervertebral disc degeneration and regeneration

    Science.gov (United States)

    Molinos, Maria; Almeida, Catarina R.; Caldeira, Joana; Cunha, Carla; Gonçalves, Raquel M.; Barbosa, Mário A.

    2015-01-01

    Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a problem with a heavy economic burden, which has been increasing in prevalence as populations age. Deeper knowledge of the complex spatial and temporal orchestration of cellular interactions and extracellular matrix remodelling is critical to improve current IVD therapies, which have so far proved unsatisfactory. Inflammation has been correlated with degenerative disc disease but its role in discogenic pain and hernia regression remains controversial. The inflammatory response may be involved in the onset of disease, but it is also crucial in maintaining tissue homeostasis. Furthermore, if properly balanced it may contribute to tissue repair/regeneration as has already been demonstrated in other tissues. In this review, we focus on how inflammation has been associated with IVD degeneration by describing observational and in vitro studies as well as in vivo animal models. Finally, we provide an overview of IVD regenerative therapies that target key inflammatory players. PMID:25673296

  15. Investigation on the Performance of UPQC-Q for Voltage Sag Mitigation and PQ Improvement at a Critical Load Point

    OpenAIRE

    Basu, Malabika; Das, S. P.; Dubey, Gopal

    2008-01-01

    The unified power quality conditioner (UPQC) is one of the major custom power solutions, which is capable of mitigating the effect of supply voltage sag at the load end or at the point of common coupling (PCC) in a distributed network. It also prevents the propagation of the load current harmonics to the utility and improves the input power factor of the load. The control of series compensator (SERC) of the UPQC is such that it injects voltage in quadrature advance to the supply current. Thus...

  16. Do out-of-body and near-death experiences point towards the reality of nonlocal consciousness? A critical evaluation

    Directory of Open Access Journals (Sweden)

    Pieter Craffert

    2015-07-01

    Full Text Available In recent years there was a steady flow of academic studies claiming that the mind or consciousness can function independently from a working brain. Such research is presented with great confidence as a scientific breakthrough and one that will alter received views on both humanity and the meaning of life as well as medical science in general and neuroscience in particular. In this article the three major streams of evidence for the existence of nonlocal consciousness are critically evaluated. Neither the testimonies of thousands of experients nor research on cardiac arrest patients or experimental research on veridical perception during out-of-body experiences at this stage provide sufficient evidence for such claims about nonlocal consciousness. Extraordinary claims about paradigm chances in the scientific world should be supported by uncontroversial and high quality evidence, which is currently not available.

  17. [Design of a Hazard Analysis and Critical Control Points (HACCP) plan to assure the safety of a bologna product produced by a meat processing plant].

    Science.gov (United States)

    Bou Rached, Lizet; Ascanio, Norelis; Hernández, Pilar

    2004-03-01

    The Hazard Analysis and Critical Control Point (HACCP) is a systematic integral program used to identify and estimate the hazards (microbiological, chemical and physical) and the risks generated during the primary production, processing, storage, distribution, expense and consumption of foods. To establish a program of HACCP has advantages, being some of them: to emphasize more in the prevention than in the detection, to diminish the costs, to minimize the risk of manufacturing faulty products, to allow bigger trust to the management, to strengthen the national and international competitiveness, among others. The present work is a proposal based on the design of an HACCP program to guarantee the safety of the Bologna Special Type elaborated by a meat products industry, through the determination of hazards (microbiological, chemical or physical), the identification of critical control points (CCP), the establishment of critical limits, plan corrective actions and the establishment of documentation and verification procedures. The used methodology was based in the application of the seven basic principles settled down by the Codex Alimentarius, obtaining the design of this program. In view of the fact that recently the meat products are linked with pathogens like E. coli O157:H7 and Listeria monocytogenes, these were contemplated as microbiological hazard for the establishment of the HACCP plan whose application will guarantee the obtaining of a safe product.

  18. A critical evaluation in the delivery of the ultrasound practice: the point of view of the radiologist

    Directory of Open Access Journals (Sweden)

    Giovanni Stasi

    2015-03-01

    Full Text Available The authors describe the benefits and risks of massive and widespread diffusion of ultrasound diagnostics for public and affiliated centers. The main considerations regarding organizational aspects, cultural and qualitative assistance of various medical professionals belonging to the Public Service, unfortunately point out that not all lesions found are able to use the same standardized diagnostic criteria. The risks of errors in diagnostic consumerism, with consequent multiplication of exams, often redundant, are on the rise. The authors urge greater control and the adoption of stricter criteria for the selection of clinical skills of operators who are responsible for this delicate, difficult and at the same time valuable diagnostic task, moreover, of great social value.

  19. Novel superconductivity at the magnetic critical point in heavy-fermion systems: a systematic study of NQR under pressure

    International Nuclear Information System (INIS)

    Kitaoka, Y; Kawasaki, S; Kawasaki, Y; Mito, T; Zheng, G-q

    2007-01-01

    We report on the discovery of exotic superconductivity (SC) and novel magnetism in heavy-fermion (HF) compounds, CeCu 2 Si 2 , CeRhIn 5 and CeIn 3 , on the verge of antiferromagnetism (AFM) through nuclear-quadrupole-resonance (NQR) measurements under pressure (P). The exotic SC in a homogeneous CeCu 2 Si 2 (T c = 0.7 K) revealed antiferromagnetic critical fluctuations at the border to AFM or a marginal AFM. Remarkably, it has been found that the application of magnetic field induces a spin-density-wave (SDW) transition by suppressing the SC near the upper critical field. Furthermore, the uniform mixed phase of SC and AFM in CeCu 2 (Si 1-x Ge x ) 2 emerges on a microscopic level, once a tiny amount of 1% Ge (x = 0.01) is substituted for Si to expand its lattice. The application of minute pressure (P∼0.19 GPa) suppresses the sudden emergence of the AFM caused by doping Ge. The persistence of the low-lying magnetic excitations at temperatures lower than T c and T N is ascribed to the uniform mixed phase of SC and AFM. Likewise, the P-induced HF superconductor CeRhIn 5 coexists with AFM on a microscopic level in P = 1.5-1.9 GPa. It is demonstrated that SC does not yield any trace of gap opening in low-lying excitations below the onset temperature, presumably associated with an amplitude fluctuation of superconducting order parameter. The unconventional gapless nature of SC in the low-lying excitation spectrum emerges due to the uniform mixed phase of AFM and SC. By contrast, in CeIn 3 , the P-induced phase separation of AFM and paramagnetism (PM) takes place without any trace for a quantum phase transition. The outstanding finding is that SC sets in at both the phases magnetically separated into AFM and PM in P = 2.28-2.5 GPa. A new type of SC forms the uniform mixed phase with AFM and the HF SC occurs in PM. We propose that the magnetic excitations such as spin-density fluctuations induced by the first-order phase transition from AFM to PM might mediate attractive

  20. Second order degenerate elliptic equations

    International Nuclear Information System (INIS)

    Duong Minh Duc.

    1988-08-01

    Using an improved Sobolev inequality we study a class of elliptic operators which is degenerate inside the domain and strongly degenerate near the boundary of the domain. Our results are applicable to the L 2 -boundary value problem and the mixed boundary problem. (author). 18 refs

  1. Intervertebral disc degeneration in dogs

    NARCIS (Netherlands)

    Bergknut, Niklas

    Back pain is common in both dogs and humans, and is often associated with intervertebral disc (IVD) degeneration. The IVDs are essential structures of the spine and degeneration can ultimately result in diseases such as IVD herniation or spinal instability. In order to design new treatments halting

  2. Intervertebral disc degeneration in dogs

    NARCIS (Netherlands)

    Bergknut, N.|info:eu-repo/dai/nl/314418059

    2011-01-01

    Back pain is common in both dogs and humans, and is often associated with intervertebral disc (IVD) degeneration. The IVDs are essential structures of the spine and degeneration can ultimately result in diseases such as IVD herniation or spinal instability. In order to design new treatments halting

  3. [Quality assurance in food production in Europe according to ISO 90000 and HACCP (Hazard Analysis and Critical Control Points)].

    Science.gov (United States)

    Jouve, J L

    1996-12-01

    HACCP is intended to make food protection programs evolve from a mainly retrospective quality control toward a preventative quality assurance approach and to provide an increased confidence in food safety. In parallel, the continuous evolution of quality concepts in the food industry resulted in the development of quality systems and quality assurance techniques with regard to the EN 29,000 (ISO 9000) series of standards. Specific to the food industry, HACCP can be seen as a very effective method to prepare specific Safety Assurance Plans (cf. the quality assurance plan concept) within a quality systems approach (Jouve, 1993). By reference to ISO 8402, a Quality Assurance Plan (QAP) basically sets out "the specific quality practices, resources and sequence of activities relevant to a particular product, service, contract or project". Quality assurance plans are more particularly useful for projects relating to new products or processes and/or comprising inter-related tasks whose interaction may be complex. In addition, in contractual or regulatory situations, such plans can be used to demonstrate the supplier's capability to meet identified objectives, specification or standards. In the food industry, the management of safety is a critical and complex issue which fits very well in the scope of application of a specific QAP; it is also where the use of HACCP is otherwise recommended by priority.

  4. Determination of source terms in a degenerate parabolic equation

    International Nuclear Information System (INIS)

    Cannarsa, P; Tort, J; Yamamoto, M

    2010-01-01

    In this paper, we prove Lipschitz stability results for inverse source problems relative to parabolic equations. We use the method introduced by Imanuvilov and Yamamoto in 1998 based on Carleman estimates. What is new here is that we study a class of one-dimensional degenerate parabolic equations. In our model, the diffusion coefficient vanishes at one extreme point of the domain. Instead of the classical Carleman estimates obtained by Fursikov and Imanuvilov for non degenerate equations, we use and extend some recent Carleman estimates for degenerate equations obtained by Cannarsa, Martinez and Vancostenoble. Finally, we obtain Lipschitz stability results in inverse source problems for our class of degenerate parabolic equations both in the case of a boundary observation and in the case of a locally distributed observation

  5. HYGIENE PRACTICES IN URBAN RESTAURANTS AND CHALLENGES TO IMPLEMENTING FOOD SAFETY AND HAZARD ANALYSIS CRITICAL CONTROL POINTS (HACCP) PROGRAMMES IN THIKA TOWN, KENYA.

    Science.gov (United States)

    Muinde, R K; Kiinyukia, C; Rombo, G O; Muoki, M A

    2012-12-01

    To determine the microbial load in food, examination of safety measures and possibility of implementing an Hazard Analysis Critical Control Points (HACCP) system. The target population for this study consisted of restaurants owners in Thika. Municipality (n = 30). Simple randomsamples of restaurantswere selected on a systematic sampling method of microbial analysis in cooked, non-cooked, raw food and water sanitation in the selected restaurants. Two hundred and ninety eight restaurants within Thika Municipality were selected. Of these, 30 were sampled for microbiological testing. From the study, 221 (74%) of the restaurants were ready to eat establishments where food was prepared early enough to hold and only 77(26%) of the total restaurants, customers made an order of food they wanted. 118(63%) of the restaurant operators/staff had knowledge on quality control on food safety measures, 24 (8%) of the restaurants applied these knowledge while 256 (86%) of the restaurants staff showed that food contains ingredients that were hazard if poorly handled. 238 (80%) of the resultants used weighing and sorting of food materials, 45 (15%) used preservation methods and the rest used dry foods as critical control points on food safety measures. The study showed that there was need for implementation of Hazard Analysis Critical Control Points (HACCP) system to enhance food safety. Knowledge of HACCP was very low with 89 (30%) of the restaurants applying some of quality measures to the food production process systems. There was contamination with Coliforms, Escherichia coli and Staphylococcus aureus microbial though at very low level. The means of Coliforms, Escherichia coli and Staphylococcus aureas microbial in sampled food were 9.7 x 103CFU/gm, 8.2 x 103 CFU/gm and 5.4 x 103 CFU/gm respectively with Coliforms taking the highest mean.

  6. Development of hazard analysis by critical control points (HACCP) procedures to control organic chemical hazards in the agricultural production of raw food commodities.

    Science.gov (United States)

    Ropkins, Karl; Ferguson, Andrew; Beck, Angus J

    2003-01-01

    Hazard Analysis by Critical Control Points (HACCP) is a systematic approach to the identification, assessment, and control of hazards in the food chain. Effective HACCP requires the consideration of all chemical microbiological, and physical hazards. However, current procedures focus primarily on microbiological and physical hazards, while chemical aspects of HACCP have received relatively little attention. In this article we discuss the application of HACCP to organic chemical contaminants and the problems that are likely to be encountered in agriculture. We also present generic templates for the development of organic chemical contaminant HACCP procedures for selected raw food commodities, that is, cereal crops,raw meats, and milk.

  7. Two-point function of a d =2 quantum critical metal in the limit kF→∞ , Nf→0 with NfkF fixed

    Science.gov (United States)

    Säterskog, Petter; Meszena, Balazs; Schalm, Koenraad

    2017-10-01

    We show that the fermionic and bosonic spectrum of d =2 fermions at finite density coupled to a critical boson can be determined nonperturbatively in the combined limit kF→∞ ,Nf→0 with NfkF fixed. In this double scaling limit, the boson two-point function is corrected but only at one loop. This double scaling limit therefore incorporates the leading effect of Landau damping. The fermion two-point function is determined analytically in real space and numerically in (Euclidean) momentum space. The resulting spectrum is discontinuously connected to the quenched Nf→0 result. For ω →0 with k fixed the spectrum exhibits the distinct non-Fermi-liquid behavior previously surmised from the RPA approximation. However, the exact answer obtained here shows that the RPA result does not fully capture the IR of the theory.

  8. Critical Issues and Key Points from the Survey to the Creation of the Historical Building Information Model: the Case of Santo Stefano Basilica

    Science.gov (United States)

    Castagnetti, C.; Dubbini, M.; Ricci, P. C.; Rivola, R.; Giannini, M.; Capra, A.

    2017-05-01

    The new era of designing in architecture and civil engineering applications lies in the Building Information Modeling (BIM) approach, based on a 3D geometric model including a 3D database. This is easier for new constructions whereas, when dealing with existing buildings, the creation of the BIM is based on the accurate knowledge of the as-built construction. Such a condition is allowed by a 3D survey, often carried out with laser scanning technology or modern photogrammetry, which are able to guarantee an adequate points cloud in terms of resolution and completeness by balancing both time consuming and costs with respect to the request of final accuracy. The BIM approach for existing buildings and even more for historical buildings is not yet a well known and deeply discussed process. There are still several choices to be addressed in the process from the survey to the model and critical issues to be discussed in the modeling step, particularly when dealing with unconventional elements such as deformed geometries or historical elements. The paper describes a comprehensive workflow that goes through the survey and the modeling, allowing to focus on critical issues and key points to obtain a reliable BIM of an existing monument. The case study employed to illustrate the workflow is the Basilica of St. Stefano in Bologna (Italy), a large monumental complex with great religious, historical and architectural assets.

  9. Dynamics of pulsed laser ablation plasmas in high-density CO2 near the critical point investigated by time-resolved shadowgraph imaging

    Science.gov (United States)

    Urabe, Keiichiro; Kato, Toru; Himeno, Shohei; Kato, Satoshi; Stauss, Sven; Baba, Motoyoshi; Suemoto, Tohru; Terashima, Kazuo

    2013-09-01

    Pulsed laser ablation (PLA) plasmas generated in high-density gases and liquids are promising for the synthesis of nanomaterials. However, the characteristics of such plasmas are still not well understood. In order to improve the understandings of PLA plasmas in high-density fluids including gases, liquids, and supercritical fluids (SCFs), we have investigated the dynamics of PLA plasmas in high-density carbon dioxide (CO2) . We report on experimental results of time-resolved shadowgraph imaging, from the generation of plasma plume to the extinction of cavitation bubbles. Shadowgraph images revealed that the PLA plasma dynamics showed two distinct behaviors. These are divided by gas-liquid coexistence curve and the so-called Widom line, which separates gas-like and liquid-like SCF domains. Furthermore, cavitation bubble observed in liquid CO2 near the critical point showed peculiar characteristics, the formation of an inner bubble and an outer shell structure, which so far has never been reported. The experiments indicate that thermophysical properties of PLA plasmas can be tuned by controlling solvent temperature and pressure around the critical point, which may be useful for materials processing. This work was supported financially in part by a Grant-in-Aid for Scientific Research on Innovative Areas (No. 21110002) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

  10. Family-Specific Degenerate Primer Design: A Tool to Design Consensus Degenerated Oligonucleotides

    Science.gov (United States)

    Goñi, Sandra Elizabeth; Lozano, Mario Enrique

    2013-01-01

    Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer software, for which the starting point is a multiple alignment of related amino acids or nucleotide sequences. To assess their efficiency, four different genome collections were used, covering a wide range of genomic lengths: Arenavirus (10 × 104 nucleotides), Baculovirus (0.9 × 105 to 1.8 × 105 bp), Lactobacillus sp. (1 × 106 to 2 × 106 bp), and Pseudomonas sp. (4 × 106 to 7 × 106 bp). In each case, FAS-DPD designed primers were tested computationally to measure specificity. Designed primers for Arenavirus and Baculovirus were tested experimentally. The method presented here is useful for designing degenerate primers on collections of related protein sequences, allowing detection of new family members. PMID:23533783

  11. [Lattice degeneration of the retina].

    Science.gov (United States)

    Boĭko, E V; Suetov, A A; Mal'tsev, D S

    2014-01-01

    Lattice degeneration of the retina is a clinically important type of peripheral retinal dystrophies due to its participation in the pathogenesis of rhegmatogenous retinal detachment. In spite of extensive epidemiological, morphological, and clinical data, the question on causes of this particular type of retinal dystrophies currently remains debatable. Existing hypotheses on pathogenesis of retinal structural changes in lattice degeneration explain it to a certain extent. In clinical ophthalmology it is necessary to pay close attention to this kind of degenerations and distinguish between cases requiring preventive treatment and those requiring monitoring.

  12. Point-of-care gastrointestinal and urinary tract sonography in daily evaluation of gastrointestinal dysfunction in critically ill patients (GUTS Protocol).

    Science.gov (United States)

    Perez-Calatayud, Angel Augusto; Carrillo-Esper, Raul; Anica-Malagon, Eduardo Daniel; Briones-Garduño, Jesus Carlos; Arch-Tirado, Emilio; Wise, Robert; Malbrain, Manu L N G

    2018-01-01

    There is currently a lack of universally accepted criteria for gastrointestinal (GI) failure or dysfunction in critical care. Moreover, the clinical assessment of intestinal function is notoriously difficult and thus often goes unrecognized, contributing to poor outcomes. A recent grading system has been proposed to define acute gastrointestinal injury (AGI) in conjunction with other organ function scores (e.g., SOFA). Ultrasonography has become widely accepted as a diagnostic tool for GI problems and pathology. We propose a sonographic examination of the abdomen, using the GUTS protocol (gastrointestinal and urinary tract sonography) in critically ill patients as part of the point-of-care ultrasound evaluation in patients with AGI. This article reviews possible applications of ultrasonography that may be relevant to monitor the GI function in critically ill patients. The GI ultrasound protocol (GUTS) focuses on four gastrointestinal endpoints: gastrointestinal diameter, mucosal thickness, peristalsis, and blood flow. Moreover, it is possible to examine the urinary tract and kidney function. Real-time ultrasound with the GUTS protocol is a simple, inexpensive, bedside imaging technique that can provide anatomical and functional information of the GI tract. Further studies are needed to investigate the utility of GUTS with other parameters, such as GI biomarkers, AGI class, and clinical outcomes.

  13. Degenerate asymptotic perturbation theory

    International Nuclear Information System (INIS)

    Hunziker, W.; Pillet, C.A.

    1983-01-01

    Asymptotic Rayleigh-Schroedinger perturbation theory for discrete eigenvalues is developed systematically in the general degenerate case. For this purpose we study the spectral properties of mxm - matrix functions A(kappa) of a complex variable kappa which have an asymptotic expansion ΣAsub(k)kappasup(k) as kappa->0. We show that asymptotic expansions for groups of eigenvalues and for the corresponding spectral projections of A(kappa) can be obtained from the set [Asub(k)] by analytic perturbation theory. Special attention is given to the case where A(kappa) is Borel-summable in some sector originating from kappa=0 with opening angle >π. Here we prove that the asymptotic series describe individual eigenvalues and eigenprojections of A(kappa) which are shown to be holomorphic in S near kappa=0 and Borel summable if Asub(k)sup(*)=Asub(k) for all k. We then fit these results into the scheme of Rayleigh-Schroedinger perturbation theory and we give some examples of asymptotic estimates for Schroedinger operators. (orig.)

  14. Degenerate ground states and multiple bifurcations in a two-dimensional q-state quantum Potts model.

    Science.gov (United States)

    Dai, Yan-Wei; Cho, Sam Young; Batchelor, Murray T; Zhou, Huan-Qiang

    2014-06-01

    We numerically investigate the two-dimensional q-state quantum Potts model on the infinite square lattice by using the infinite projected entangled-pair state (iPEPS) algorithm. We show that the quantum fidelity, defined as an overlap measurement between an arbitrary reference state and the iPEPS ground state of the system, can detect q-fold degenerate ground states for the Z_{q} broken-symmetry phase. Accordingly, a multiple bifurcation of the quantum ground-state fidelity is shown to occur as the transverse magnetic field varies from the symmetry phase to the broken-symmetry phase, which means that a multiple-bifurcation point corresponds to a critical point. A (dis)continuous behavior of quantum fidelity at phase transition points characterizes a (dis)continuous phase transition. Similar to the characteristic behavior of the quantum fidelity, the magnetizations, as order parameters, obtained from the degenerate ground states exhibit multiple bifurcation at critical points. Each order parameter is also explicitly demonstrated to transform under the Z_{q} subgroup of the symmetry group of the Hamiltonian. We find that the q-state quantum Potts model on the square lattice undergoes a discontinuous (first-order) phase transition for q=3 and q=4 and a continuous phase transition for q=2 (the two-dimensional quantum transverse Ising model).

  15. Getting superstring amplitudes by degenerating Riemann surfaces

    International Nuclear Information System (INIS)

    Matone, Marco; Volpato, Roberto

    2010-01-01

    We explicitly show how the chiral superstring amplitudes can be obtained through factorisation of the higher genus chiral measure induced by suitable degenerations of Riemann surfaces. This powerful tool also allows to derive, at any genera, consistency relations involving the amplitudes and the measure. A key point concerns the choice of the local coordinate at the node on degenerate Riemann surfaces that greatly simplifies the computations. As a first application, starting from recent ansaetze for the chiral measure up to genus five, we compute the chiral two-point function for massless Neveu-Schwarz states at genus two, three and four. For genus higher than three, these computations include some new corrections to the conjectural formulae appeared so far in the literature. After GSO projection, the two-point function vanishes at genus two and three, as expected from space-time supersymmetry arguments, but not at genus four. This suggests that the ansatz for the superstring measure should be corrected for genus higher than four.

  16. Computed tomography of Wallerian degeneration

    International Nuclear Information System (INIS)

    Uchino, Akira; Maeda, Fumihiko

    1986-01-01

    CT findings of wallerian degeneration of the pyramidal tract at the midbrain (atrophy of cerebral peduncle following cerebrovascular accident) were studied in 34 patients (44 CT scans) with old cerebrovascular accidents. Severe atrophy of cerebral peduncle was noted when the ipsilateral motor cortex was involved. However, when the posterior limb of the internal capsule was involved, atrophy of the ipsilateral cerebral peduncle was mild. In this series, the shortest interval between cerebrovascular accident and wallerian degeneration was 8 month. (author)

  17. Policy on Hazard Analysis and Critical Control Point (HACCP) and adherence to food preparation guidelines: a cross sectional survey of stakeholders in food service in Kumasi, Ghana.

    Science.gov (United States)

    Agyei-Baffour, Peter; Sekyere, Kofi Boateng; Addy, Ernestine Akosua

    2013-11-04

    Food borne diseases claim more lives and are growing public health concerns. Simple preventive techniques such as adoption and adherence to hazard analysis and critical control point (HACCP) policy can significantly reduce this disease burden. Though food screening and inspection are done, the ultimate regulation, Hazard Analysis and Critical Control Point, which is known and accepted worldwide, appears not to be popular among food operators in Ghana. This paper examines the level of awareness of the existence of policy on hazard analysis and critical control point (HACCP) and its adherence to food preparation guidelines among food service providers in Ghana. The results revealed the mean age of food providers as 33.1 years with a standard deviation of 7.5, range of 18-55 years, more females, in full time employment and with basic education. Of the fifty institutional managers, 42 (84%) were senior officers and had worked for more than five years. Education and type of food operator had strong statistically significant relationship with the implementation of HCCP policy and adherence with food preparation guidelines. The enforcement of HACCP policy and adherence with food safety guidelines was led by the Ghana Tourist Board, Public Health officers, and KMA, respectively. While a majority of food operators 373/450 (83.3%) did not know HACCP policy is part of food safety guidelines, staff of food safety law enforcement 44/50 (88%) confirmed knowing that food operators were not aware of the HACCP policy. The study documents evidence on the practice of food safety principles or HACCP policy or adherence to food preparation guidelines. Existing food safety guidelines incorporate varying principles of HACCP, however, awareness is low among food operators. The implication is that food production is likely to fall short of acceptable standards and not be wholesome putting consumers at health risk. Repeating this study in rural and urban areas in Ghana is necessary to

  18. Policy on Hazard Analysis and Critical Control Point (HACCP) and adherence to food preparation guidelines: a cross sectional survey of stakeholders in food service in Kumasi, Ghana

    Science.gov (United States)

    2013-01-01

    Background Food borne diseases claim more lives and are growing public health concerns. Simple preventive techniques such as adoption and adherence to hazard analysis and critical control point (HACCP) policy can significantly reduce this disease burden. Though food screening and inspection are done, the ultimate regulation, Hazard Analysis and Critical Control Point, which is known and accepted worldwide, appears not to be popular among food operators in Ghana. This paper examines the level of awareness of the existence of policy on hazard analysis and critical control point (HACCP) and its adherence to food preparation guidelines among food service providers in Ghana. Results The results revealed the mean age of food providers as 33.1 years with a standard deviation of 7.5, range of 18–55 years, more females, in full time employment and with basic education. Of the fifty institutional managers, 42 (84%) were senior officers and had worked for more than five years. Education and type of food operator had strong statistically significant relationship with the implementation of HCCP policy and adherence with food preparation guidelines. The enforcement of HACCP policy and adherence with food safety guidelines was led by the Ghana Tourist Board, Public Health officers, and KMA, respectively. While a majority of food operators 373/450 (83.3%) did not know HACCP policy is part of food safety guidelines, staff of food safety law enforcement 44/50 (88%) confirmed knowing that food operators were not aware of the HACCP policy. Conclusion The study documents evidence on the practice of food safety principles or HACCP policy or adherence to food preparation guidelines. Existing food safety guidelines incorporate varying principles of HACCP, however, awareness is low among food operators. The implication is that food production is likely to fall short of acceptable standards and not be wholesome putting consumers at health risk. Repeating this study in rural and urban

  19. Wavelet Transform Analysis of the Power Spectrum of Centre of Pressure Signals to Detect the Critical Point Interval of Postural Control

    Science.gov (United States)

    Singh, Neeraj Kumar; Snoussi, Hichem; Hewson, David; Duchêne, Jacques

    The aim of this study was to develop a method to detecting the critical point interval (CPI) when sensory feedback is used as part of a closed-loop postural control strategy. Postural balance was evaluated using centre of pressure (COP) displacements from a force plate for 17 control and 10 elderly subjects under eyes open, eyes closed, and vibration conditions. A modified local-maximum-modulus wavelet transform analysis using the power spectrum of COP signals was used to calculate CPI. Lower CPI values indicate increased closed-loop postural control with a quicker response to sensory input. Such a strategy requires greater energy expenditure due to the repeated muscular interventions to remain stable. The CPI for elderly occurred significantly quicker than for controls, indicating tighter control of posture. Similar results were observed for eyes closed and vibration conditions. The CPI parameter can be used to detect differences in postural control due to ageing.

  20. Ellipsometric study of the temperature dependences of the dielectric function and the critical points of AlSb at temperatures from 300 to 803 K

    Energy Technology Data Exchange (ETDEWEB)

    Park, Han Gyeol; Kim, Tae Jung; Hwang, Soon Yong; Kim, Jun Young; Choi, Jun Ho; Kim, Young Dong [Kyung Hee University, Seoul (Korea, Republic of); Shin, Sang Hoon; Song, Jin Dong [Korea Institute of Science and Technology, Seoul (Korea, Republic of)

    2014-08-15

    We report the complex pseudodielectric function <ε> = <ε{sub 1} > + i<ε{sub 2} > of an oxide-free AlSb film for energies from 0.7 to 5.0 eV and temperatures from 300 to 803 K. The 1.5-μm-thick film was grown on a (001) GaAs substrate by using molecular beam epitaxy. We maintained the film in an ultrahigh vacuum to prevent oxidation artifacts and used a rotating-compensator ellipsometer to obtain the optical properties. Critical-point (CP) energies were obtained by numerically calculating second energy derivatives of the data. Blue shifts of the CP energies and sharper structures were observed with decreasing temperature. The calculated CP energies were fit to a linear equation.

  1. Field-Induced Quantum Critical Point and Nodal Superconductivity in the Heavy-Fermion Superconductor Ce_{2}PdIn_{8}

    Directory of Open Access Journals (Sweden)

    J. K. Dong

    2011-09-01

    Full Text Available The in-plane resistivity ρ and thermal conductivity κ of the heavy-fermion superconductor Ce_{2}PdIn_{8} single crystals were measured down to 50 mK. A field-induced quantum critical point, occurring at the upper critical field H_{c2}, is demonstrated from the ρ(T∼T near H_{c2} and ρ(T∼T^{2} when further increasing the field. The large residual linear term κ_{0}/T at zero field and the rapid increase of κ(H/T at low field give evidence for nodal superconductivity in Ce_{2}PdIn_{8}. The jump of κ(H/T near H_{c2} suggests a first-order-like phase transition at low temperature. These results mimic the features of the famous CeCoIn_{5} superconductor, implying that Ce_{2}PdIn_{8} may be another interesting compound to investigate for the interplay between magnetism and superconductivity.

  2. Effect of stereotactic dosimetric end points on overall survival for Stage I non–small cell lung cancer: A critical review

    Energy Technology Data Exchange (ETDEWEB)

    Mulryan, Kathryn; Leech, Michelle; Forde, Elizabeth, E-mail: eforde@tcd.ie

    2015-01-01

    Stereotactic body radiation therapy (SBRT) delivers a high biologically effective dose while minimizing toxicities to surrounding tissues. Within the scope of clinical trials and local practice, there are inconsistencies in dosimetrics used to evaluate plan quality. The purpose of this critical review was to determine if dosimetric parameters used in SBRT plans have an effect on local control (LC), overall survival (OS), and toxicities. A database of relevant trials investigating SBRT for patients with early-stage non–small cell lung cancer was compiled, and a table of dosimetric variables used was created. These parameters were compared and contrasted for LC, OS, and toxicities. Dosimetric end points appear to have no effect on OS or LC. Incidences of rib fractures correlate with a lack of dose-volume constraints (DVCs) reported. This review highlights the great disparity present in clinical trials reporting dosimetrics, DVCs, and toxicities for lung SBRT. Further evidence is required before standard DVCs guidelines can be introduced. Dosimetric end points specific to stereotactic treatment planning have been proposed but require further investigation before clinical implementation.

  3. Safety and Effectiveness of Bone Marrow Cell Concentrate in the Treatment of Chronic Critical Limb Ischemia Utilizing a Rapid Point-of-Care System

    Directory of Open Access Journals (Sweden)

    Venkatesh Ponemone

    2017-01-01

    Full Text Available Critical limb ischemia (CLI is the end stage of lower extremity peripheral vascular disease (PVD in which severe obstruction of blood flow results in ischemic rest pain, ulcers and/or gangrene, and a significant risk of limb loss. This open-label, single-arm feasibility study evaluated the safety and therapeutic effectiveness of autologous bone marrow cell (aBMC concentrate in revascularization of CLI patients utilizing a rapid point-of-care device. Seventeen (17 no-option CLI patients with ischemic rest pain were enrolled in the study. Single dose of aBMC, prepared utilizing an intraoperative point-of-care device, the Res-Q™ 60 BMC system, was injected intramuscularly into the afflicted limb and patients were followed up at regular intervals for 12 months. A statistically significant improvement in Ankle Brachial Index (ABI, Transcutaneous Oxygen Pressure (TcPO2, mean rest pain and intermittent claudication pain scores, wound/ ulcer healing, and 6-minute walking distance was observed following aBMC treatment. Major amputation-free survival (mAFS rate and amputation-free rates (AFR at 12 months were 70.6% and 82.3%, respectively. In conclusion, aBMC injections were well tolerated with improved tissue perfusion, confirming the safety, feasibility, and preliminary effectiveness of aBMC treatment in CLI patients.

  4. Can the watershed non-point phosphorus pollution be interpreted by critical soil properties? A new insight of different soil P states.

    Science.gov (United States)

    Lin, Chen; Ma, Ronghua; Xiong, Junfeng

    2018-07-01

    The physicochemical properties of surface soil play a key role in the fate of watershed non-point source pollution. Special emphasis is needed to identify soil properties that are sensitive to both particulate P (PP) pollution and dissolved P (DP) pollution, which is essential for watershed environmental management. The Chaohu Lake basin, a typical eutrophic lake in China, was selected as the study site. The spatial features of the Non-point Source (NPS) PP loads and DP loads were calculated simultaneously based on the integration of sediment delivery distributed model (SEDD) and pollution loads (PLOAD) model. Then several critical physicochemical soil properties, especially various soil P compositions, were innovatively introduced to determine the response of the critical soil properties to NPS P pollution. The findings can be summarized: i) the mean PP load value of the different sub-basins was 5.87 kg, and PP pollution is regarded to be the primary NPS P pollution state, while the DP loads increased rapidly under the rapid urbanization process. ii) iron-bound phosphorus (Fe-P) and aluminum-bound phosphorus (Al-P) are the main components of available P and showed the most sensitive responses to NPS PP pollution, and the correlation coefficients were approximately 0.9. Otherwise, the residual phosphorus (Res-P) was selected as a sensitive soil P state that was significantly negatively correlated with the DP loads. iii) The DP and PP concentrations were represented differently when they were correlated with various soil properties, and the clay proportion was strongly negatively related to the PP loads. Meanwhile, there is a non-linear relationship between the DP loads and the critical soil properties, such as Fe and Total Nitrogen (TN) concentrations. Specifically, a strong inhibitory effect of TN concentration on the DP load was apparent in the Nanfei river (NF) and Paihe (PH) river basins where the R 2 reached 0.67, which contrasts with the relatively poor

  5. Time-resolved study of electron-hole plasmas near the liquid-gas critical point in Si: Evidence for a second condensed phase

    Science.gov (United States)

    Smith, L. M.; Wolfe, J. P.

    1995-03-01

    At low temperatures and sufficient densities, free excitons in Si and Ge undergo simultaneous gas-liquid and insulator-metal transitions into droplets of electron-hole liquid. Some previous theoretical and experimental studies have suggested that, under certain values of density and temperature, there may be separate metal-insulator and liquid-gas transitions. In the present paper, we examine the difficult transcritical region for electron-hole liquid formation in unstressed Si using time- and space-resolved photoluminescence spectroscopy. Using the latest models for the luminescence of electron-hole plasma and small excitonic complexes (EC's), we have succeeded in characterizing the complicated luminescence spectra both above and below the liquid-gas critical temperature [Tc(LG)~=24.5 K] with a relatively small number of free parameters. Near the liquid-gas critical point the luminescence spectra are analyzed as contributions from four lines: the high-density electron-hole liquid (EHL), a lower-density electron-hole plasma (EHP), free excitons (FE's), and excitonic complexes. After a sufficient thermalization time, the temperature of all phases settles to a value indistinguishable from the lattice temperature. The line shapes of FE's and EC's are calculated using previously established parameters. Using the latest band-renormalization theory, the pair density of the plasma phases (EHL and EHP) determines both the position and the shape of the spectrum. Therefore the analysis of these complex spectra is reduced to five free parameters: A single parameter describing the intensity of the FE line (the intensity of the EC line shape is linked to that of the FE using an experimentally determined scaling relation), the intensities of the two plasma components EHL and EHP, and the pair densities of these two plasmas. These parameters are sufficient to characterize the spectra over a wide range of particle density and temperature. The EHP density obtained in this way is

  6. Tyro3 Modulates Mertk-Associated Retinal Degeneration.

    Directory of Open Access Journals (Sweden)

    Douglas Vollrath

    2015-12-01

    Full Text Available Inherited photoreceptor degenerations (IPDs are the most genetically heterogeneous of Mendelian diseases. Many IPDs exhibit substantial phenotypic variability, but the basis is usually unknown. Mutations in MERTK cause recessive IPD phenotypes associated with the RP38 locus. We have identified a murine genetic modifier of Mertk-associated photoreceptor degeneration, the C57BL/6 (B6 allele of which acts as a suppressor. Photoreceptors degenerate rapidly in Mertk-deficient animals homozygous for the 129P2/Ola (129 modifier allele, whereas animals heterozygous for B6 and 129 modifier alleles exhibit an unusual intermixing of degenerating and preserved retinal regions, with females more severely affected than males. Mertk-deficient mice homozygous for the B6 modifier allele display degeneration only in the far periphery, even at 8 months of age, and have improved retinal function compared to animals homozygous for the 129 allele. We genetically mapped the modifier to an approximately 2-megabase critical interval that includes Tyro3, a paralog of Mertk. Tyro3 expression in the outer retina varies with modifier genotype in a manner characteristic of a cis-acting expression quantitative trait locus (eQTL, with the B6 allele conferring an approximately three-fold higher expression level. Loss of Tyro3 function accelerates the pace of photoreceptor degeneration in Mertk knockout mice, and TYRO3 protein is more abundant in the retinal pigment epithelium (RPE adjacent to preserved central retinal regions of Mertk knockout mice homozygous for the B6 modifier allele. Endogenous human TYRO3 protein co-localizes with nascent photoreceptor outer segment (POS phagosomes in a primary RPE cell culture assay, and expression of murine Tyro3 in cultured cells stimulates phagocytic ingestion of POS. Our findings demonstrate that Tyro3 gene dosage modulates Mertk-associated retinal degeneration, provide strong evidence for a direct role for TYRO3 in RPE phagocytosis

  7. Deficiency of adaptive immunity does not interfere with Wallerian degeneration.

    Directory of Open Access Journals (Sweden)

    Christopher R Cashman

    Full Text Available Following injury, distal axons undergo the process of Wallerian degeneration, and then cell debris is cleared to create a permissive environment for axon regeneration. The innate and adaptive immune systems are believed to be critical for facilitating the clearance of myelin and axonal debris during this process. However, immunodeficient animal models are regularly used in transplantation studies investigating cell therapies to modulate the degenerative/regenerative response. Given the importance of the immune system in preparing a permissive environment for regeneration by clearing debris, animals lacking, in part or in full, a functional immune system may have an impaired ability to regenerate due to poor myelin clearance, and may, thus, be poor hosts to study modulators of regeneration and degeneration. To study this hypothesis, three different mouse models with impaired adaptive immunity were compared to wild type animals in their ability to degenerate axons and clear myelin debris one week following sciatic nerve transection. Immunofluorescent staining for axons and quantitation of axon density with nerve histomorphometry of the distal stump showed no consistent discrepancy between immunodeficient and wild type animals, suggesting axons tended to degenerate equally between the two groups. Debris clearance was assessed by macrophage density and relative myelin basic protein expression within the denervated nerve stump, and no consistent impairment of debris clearance was found. These data suggested deficiency of the adaptive immune system does not have a substantial effect on axon degeneration one week following axonal injury.

  8. Magneto-acoustic study near the quantum critical point of the frustrated quantum antiferromagnet Cs{sub 2}CuCl{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Cong, P. T., E-mail: t.pham@hzdr.de [Dresden High Magnetic Field Laboratory, Helmholtz-Zentrum Dresden-Rossendorf, D-01314 Dresden (Germany); Physics Institute, Goethe University Frankfurt, D-60438 Frankfurt am Main (Germany); Postulka, L.; Wolf, B.; Ritter, F.; Assmus, W.; Krellner, C.; Lang, M., E-mail: michael.lang@physik.uni-frankfurt.de [Physics Institute, Goethe University Frankfurt, D-60438 Frankfurt am Main (Germany); Well, N. van [Physics Institute, Goethe University Frankfurt, D-60438 Frankfurt am Main (Germany); Laboratory for Neutron Scattering and Imaging, Paul Scherrer Institute, CH-5232 Villigen (Switzerland)

    2016-10-14

    Magneto-acoustic investigations of the frustrated triangular-lattice antiferromagnet Cs{sub 2}CuCl{sub 4} were performed for the longitudinal modes c{sub 11} and c{sub 33} in magnetic fields along the a-axis. The temperature dependence of the sound velocity at zero field shows a mild softening at low temperature and displays a small kink-like anomaly at T{sub N}. Isothermal measurements at T < T{sub N} of the sound attenuation α reveal two closely spaced features of different characters on approaching the material's quantum-critical point (QCP) at B{sub s} ≈ 8.5 T for B || a. The peak at slightly lower fields remains sharp down to the lowest temperature and can be attributed to the ordering temperature T{sub N}(B). The second anomaly, which is rounded and which becomes reduced in size upon cooling, is assigned to the material's spin-liquid properties preceding the long-range antiferromagnetic ordering with decreasing temperature. These two features merge upon cooling suggesting a coincidence at the QCP. The elastic constant at lowest temperatures of our experiment at 32 mK can be well described by a Landau free energy model with a very small magnetoelastic coupling constant G/k{sub B} ≈ 2.8 K. The applicability of this classical model indicates the existence of a small gap in the magnetic excitation spectrum which drives the system away from quantum criticality.

  9. Hazard analysis and critical control point to irradiated food in Brazil; Analise de perigos e pontos criticos de controle para alimentos irradiados no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Boaratti, Maria de Fatima Guerra

    2004-07-01

    Food borne diseases, in particular gastro-intestinal infections, represent a very large group of pathologies with a strong negative impact on the health of the population because of their widespread nature. Little consideration is given to such conditions due to the fact that their symptoms are often moderate and self-limiting. This has led to a general underestimation of their importance, and consequently to incorrect practices during the preparation and preservation of food, resulting in the frequent occurrence of outbreaks involving groups of varying numbers of consumers. Despite substantial efforts in the avoidance of contamination, an upward trend in the number of outbreaks of food borne illnesses caused by non-spore forming pathogenic bacteria are reported in many countries. Good hygienic practices can reduce the level of contamination but the most important pathogens cannot presently be eliminated from most farms, nor is it possible to eliminate them by primary processing, particularly from those foods which are sold raw. Several decontamination methods exist but the most versatile treatment among them is the ionizing radiation procedure. HACCP (Hazard Analysis and Critical Control Point) is a management system in which food safety is addressed through the analysis and control of biological, chemical, and physical hazards from raw material production, procurement and handling, to manufacturing, distribution and consumption of the finished product. For successful implementation of a HACCP plan, management must be strongly committed to the HACCP concept. A firm commitment to HACCP by top management provides company employees with a sense of the importance of producing safe food. At the same time, it has to be always emphasized that, like other intervention strategies, irradiation must be applied as part of a total sanitation program. The benefits of irradiation should never be considered as an excuse for poor quality or for poor handling and storage conditions

  10. Age-related macular degeneration

    DEFF Research Database (Denmark)

    la Cour, Morten; Kiilgaard, Jens Folke; Nissen, Mogens Holst

    2002-01-01

    Age-related macular degeneration (AMD) is a common macular disease affecting elderly people in the Western world. It is characterised by the appearance of drusen in the macula, accompanied by choroidal neovascularisation (CNV) or geographic atrophy. The disease is more common in Caucasian...

  11. Age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Wanjiku Mathenge

    2014-12-01

    Full Text Available Age-related macular degeneration (AMD is a disease of the retina that usually develops in people aged 60 years and older. It affects about 8.7% of the world’s population and is the leading cause of blindness among people aged 50 and older in industrialised countries.

  12. QMRA (quantitative microbial risk assessment) and HACCP (hazard analysis and critical control points) for management of pathogens in wastewater and sewage sludge treatment and reuse.

    Science.gov (United States)

    Westrell, T; Schönning, C; Stenström, T A; Ashbolt, N J

    2004-01-01

    Hazard Analysis and Critical Control Points (HACCP) was applied for identifying and controlling exposure to pathogenic microorganisms encountered during normal sludge and wastewater handling at a 12,500 m3/d treatment plant utilising tertiary wastewater treatment and mesophilic sludge digestion. The hazardous scenarios considered were human exposure during treatment, handling, soil application and crop consumption, and exposure via water at the wetland-area and recreational swimming. A quantitative microbial risk assessment (QMRA), including rotavirus, adenovirus, haemorrhagic E. coli, Salmonella, Giardia and Cryptosporidium, was performed in order to prioritise pathogen hazards for control purposes. Human exposures were treated as individual risks but also related to the endemic situation in the general population. The highest individual health risk from a single exposure was via aerosols for workers at the belt press for sludge dewatering (virus infection risk = 1). The largest impact on the community would arise if children ingested sludge at the unprotected storage site, although in the worst-case situation the largest number of infections would arise through vegetables fertilised with sludge and eaten raw (not allowed in Sweden). Acceptable risk for various hazardous scenarios, treatment and/or reuse strategies could be tested in the model.

  13. Fermi-surface transformation across the pseudogap critical point of the cuprate superconductor La1.6 -xNd0.4SrxCuO4

    Science.gov (United States)

    Collignon, C.; Badoux, S.; Afshar, S. A. A.; Michon, B.; Laliberté, F.; Cyr-Choinière, O.; Zhou, J.-S.; Licciardello, S.; Wiedmann, S.; Doiron-Leyraud, N.; Taillefer, Louis

    2017-06-01

    The electrical resistivity ρ and Hall coefficient RH of the tetragonal single-layer cuprate La1.6 -xNd0.4SrxCuO4 were measured in magnetic fields up to H =37.5 T, large enough to access the normal state at T →0 , for closely spaced dopings p across the pseudogap critical point at p=0.23 . Below p, both coefficients exhibit an upturn at low temperature, which gets more pronounced with decreasing p . Taken together, these upturns show that the normal-state carrier density n at T =0 drops upon entering the pseudogap phase. Quantitatively, it goes from n =1 +p at p =0.24 to n =p at p =0.20 . By contrast, the mobility does not change appreciably, as revealed by the magnetoresistance. Our data are in excellent agreement with recent high-field data on YBa2Cu3Oy and La2 -xSrxCuO4 . The quantitative consistency across three different cuprates shows that a drop in carrier density from 1 +p to p is a universal signature of the pseudogap transition at T =0 . We discuss the implication of these findings for the nature of the pseudogap phase.

  14. Penerapan Hazard Analysis Critical Control Point (HACCP terhadap penurunan bahaya mikrobiologis pada makanan khusus anak berbasis hewani di Rumah Sakit Umum Daerah Dr. Soedarsono Pontianak

    Directory of Open Access Journals (Sweden)

    Widyana Lakshmi Puspita

    2010-07-01

    Full Text Available Background: One way to improve the quality of food provision in hospitals is by implementing hazard analysis critical control point (HACCP in food processing. Objective: The study aimed to identify the effect of HACCP implementation to the decrease of microbiological hazards of foods for children in particular at Nutrition Installation of Dr. Soedarso Hospital of Pontianak. Methods: The study was a quasi experiment that use multiple time series design with intervention and cassation of intervention (ABA time series chain. Samples of the study were animal based food for children, cooking utensils used preparation, processing, and distribution of the food, the food providers and food processing containers. Samples were taken 3 times before and after the implementation of HACCP, each within a week duration. Result: Average germ rate in foods and cooking utensils before implementation of HACCP was relatively high. After the implementation of HACCP there was a decrease. The result of statistical analysis showed that there were effects of HACCP implementation to the reduction of microbiological hazards in foods and cooking utensils (p<0.05. Average score of knowledge on sanitation hygiene of food and practice of sanitation hygiene of foods after HACCP implementation increased. There was an increase of average score of knowledge on food sanitation hygiene and practice of food sanitation hygiene of HACCP implementation (p<0.05. Average score of sanitation hygiene of food processing container after HACCP implementation increased. Conclusion: The implementation of HACCP could reduce microbiological hazards (germ rate of animal based special foods for children.

  15. Study on the introduction of hazard analysis and critical control point (HACCP) concept of the water quality management in water supply systems.

    Science.gov (United States)

    Yokoi, H; Embutsu, I; Yoda, M; Waseda, K

    2006-01-01

    In the latest revision in 2004, the 3rd edition, the Water Safety Plans (WSP) was newly introduced into the World Health Organization (WHO) Guidelines for Drinking Water Quality. The Hazard analysis and critical control point (HACCP) is a basic concept that underlies the WSPs, and is also known as the product quality management method in the field of food and the medical manufacturing industries. In the amendments of the Drinking Water Quality Standards in Japan, water suppliers are required to reasonably achieve both safe water and efficient water quality management. Therefore, the HACCP concept is focused as an adequate management method covering a whole process of water supply systems, in a systematic way. The purpose of this study is to investigate a practical procedure in introducing the HACCP into water quality management in Japan. In comparison to conventional applications of the HACCP, unmanageable variations of raw water quality, continuous treatment and supply, and numerous standards of water quality items need to be considered. The HACCP system is expected to achieve a quick response to improvements in water quality, accountability towards consumers and a decrease in accidents.

  16. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.

    Science.gov (United States)

    Frederick, David W; Loro, Emanuele; Liu, Ling; Davila, Antonio; Chellappa, Karthikeyani; Silverman, Ian M; Quinn, William J; Gosai, Sager J; Tichy, Elisia D; Davis, James G; Mourkioti, Foteini; Gregory, Brian D; Dellinger, Ryan W; Redpath, Philip; Migaud, Marie E; Nakamaru-Ogiso, Eiko; Rabinowitz, Joshua D; Khurana, Tejvir S; Baur, Joseph A

    2016-08-09

    NAD is an obligate co-factor for the catabolism of metabolic fuels in all cell types. However, the availability of NAD in several tissues can become limited during genotoxic stress and the course of natural aging. The point at which NAD restriction imposes functional limitations on tissue physiology remains unknown. We examined this question in murine skeletal muscle by specifically depleting Nampt, an essential enzyme in the NAD salvage pathway. Knockout mice exhibited a dramatic 85% decline in intramuscular NAD content, accompanied by fiber degeneration and progressive loss of both muscle strength and treadmill endurance. Administration of the NAD precursor nicotinamide riboside rapidly ameliorated functional deficits and restored muscle mass despite having only a modest effect on the intramuscular NAD pool. Additionally, lifelong overexpression of Nampt preserved muscle NAD levels and exercise capacity in aged mice, supporting a critical role for tissue-autonomous NAD homeostasis in maintaining muscle mass and function. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Nearly degenerate neutrinos, Supersymmetry and radiative corrections

    CERN Document Server

    Casas, J A; Ibarra, Alejandro; Navarro, I

    2000-01-01

    If neutrinos are to play a relevant cosmological role, they must be essentially degenerate with a mass matrix of the bimaximal mixing type. We study this scenario in the MSSM framework, finding that if neutrino masses are produced by a see-saw mechanism, the radiative corrections give rise to mass splittings and mixing angles that can accommodate the atmospheric and the (large angle MSW) solar neutrino oscillations. This provides a natural origin for the $\\Delta m^2_{sol} << \\Delta m^2_{atm}$ hierarchy. On the other hand, the vacuum oscillation solution to the solar neutrino problem is always excluded. We discuss also in the SUSY scenario other possible effects of radiative corrections involving the new neutrino Yukawa couplings, including implications for triviality limits on the Majorana mass, the infrared fixed point value of the top Yukawa coupling, and gauge coupling and bottom-tau unification.

  18. Sensitivity of predictions in an effective model: Application to the chiral critical end point position in the Nambu-Jona-Lasinio model

    International Nuclear Information System (INIS)

    Biguet, Alexandre; Hansen, Hubert; Brugiere, Timothee; Costa, Pedro; Borgnat, Pierre

    2015-01-01

    The measurement of the position of the chiral critical end point (CEP) in the QCD phase diagram is under debate. While it is possible to predict its position by using effective models specifically built to reproduce some of the features of the underlying theory (QCD), the quality of the predictions (e.g., the CEP position) obtained by such effective models, depends on whether solving the model equations constitute a well- or ill-posed inverse problem. Considering these predictions as being inverse problems provides tools to evaluate if the problem is ill-conditioned, meaning that infinitesimal variations of the inputs of the model can cause comparatively large variations of the predictions. If it is ill-conditioned, it has major consequences because of finite variations that could come from experimental and/or theoretical errors. In the following, we shall apply such a reasoning on the predictions of a particular Nambu-Jona-Lasinio model within the mean field + ring approximations, with special attention to the prediction of the chiral CEP position in the (T-μ) plane. We find that the problem is ill-conditioned (i.e. very sensitive to input variations) for the T-coordinate of the CEP, whereas, it is well-posed for the μ-coordinate of the CEP. As a consequence, when the chiral condensate varies in a 10MeV range, μ CEP varies far less. As an illustration to understand how problematic this could be, we show that the main consequence when taking into account finite variation of the inputs, is that the existence of the CEP itself cannot be predicted anymore: for a deviation as low as 0.6% with respect to vacuum phenomenology (well within the estimation of the first correction to the ring approximation) the CEP may or may not exist. (orig.)

  19. Effect of Ca/Al molar ratio on the growth of Cryptomeria japonica, Chamaecyparis obtusa and Chamaecyparis pisifera grown in nutrient solution culture and their critical point; Suiko saibai jokenka ni okeru sugi, hinoki, sawara no seiiku ni oyobosu Ca/Al no eikyo to critical point

    Energy Technology Data Exchange (ETDEWEB)

    Kono, Y. [Central Research Institute of Electric Power Industry, Tokyo (Japan); Umezawa, T.; Murakoshi, M. [Bio-Environment Research, Co. Ltd., Chiba (Japan)

    1998-11-10

    A solution culture is experimented for the investigation of the effect of Ca/Al on the growth of Sugi (cryptomeria), Hinoki (cypress), and Sakura (cherry tree), and of CP (critical point for the emergence of the effect of Al). The solution culture is performed in water under specified conditions, the harvest is assortedly collected after 14 weeks, and is measured for dried weight. Sugi and Hinoki wither and die at an Al concentration of 5mM, but not at an Al concentration of 1mM or less. The concentration of Ca fails to exert any significant influence. At the Al concentration of 5mM, the trees are inhibited from growing in height or trunk diameter, but not affected by Ca concentration. The dried weight shares the same trend. The dried weight begins to decrease when the mol concentration ratio of Ca/Al or (K+Ca+Mg)/Al lowers to four or less. It may be concluded that conifers are inhibited from growing when the Al concentration is 2mM or higher, Ca/Al is one or lower, or (K+Ca+Mg)/Al is five or lower. If the point where growth is inhibited by 20% or 50% is chosen as the reference point, the CP of (K+Ca+Mg)/Al will be 1 or 0.5, respectively. This means that a different reference point yields a different value. There is an experimental outcome stating that growth is not affected even when this value is 0.4 in the case of soil exposed to artificial acid rain. 22 refs., 9 figs., 1 tab.

  20. Light and inherited retinal degeneration

    OpenAIRE

    Paskowitz, D M; LaVail, M M; Duncan, J L

    2006-01-01

    Light deprivation has long been considered a potential treatment for patients with inherited retinal degenerative diseases, but no therapeutic benefit has been demonstrated to date. In the few clinical studies that have addressed this issue, the underlying mutations were unknown. Our rapidly expanding knowledge of the genes and mechanisms involved in retinal degeneration have made it possible to reconsider the potential value of light restriction in specific genetic contexts. This review summ...

  1. Point-of-Care Versus Central Laboratory Measurements of Hemoglobin, Hematocrit, Glucose, Bicarbonate and Electrolytes: A Prospective Observational Study in Critically Ill Patients.

    Directory of Open Access Journals (Sweden)

    Jérôme Allardet-Servent

    Full Text Available Rapid detection of abnormal biological values using point-of-care (POC testing allows clinicians to promptly initiate therapy; however, there are concerns regarding the reliability of POC measurements. We investigated the agreement between the latest generation blood gas analyzer and central laboratory measurements of electrolytes, bicarbonate, hemoglobin, hematocrit, and glucose.314 paired samples were collected prospectively from 51 critically ill patients. All samples were drawn simultaneously in the morning from an arterial line. BD Vacutainer tubes were analyzed in the central laboratory using Beckman Coulter analyzers (AU 5800 and DxH 800. BD Preset 3 ml heparinized-syringes were analyzed immediately in the ICU using the POC Siemens RAPIDPoint 500 blood gas system. We used CLIA proficiency testing criteria to define acceptable analytical performance and interchangeability.Biases, limits of agreement (±1.96 SD and coefficients of correlation were respectively: 1.3 (-2.2 to 4.8 mmol/L, r = 0.936 for sodium; 0.2 (-0.2 to 0.6 mmol/L, r = 0.944 for potassium; -0.9 (-3.7 to 2 mmol/L, r = 0.967 for chloride; 0.8 (-1.9 to 3.4 mmol/L, r = 0.968 for bicarbonate; -11 (-30 to 9 mg/dL, r = 0.972 for glucose; -0.8 (-1.4 to -0.2 g/dL, r = 0.985 for hemoglobin; and -1.1 (-2.9 to 0.7%, r = 0.981 for hematocrit. All differences were below CLIA cut-off values, except for hemoglobin.Compared to central Laboratory analyzers, the POC Siemens RAPIDPoint 500 blood gas system satisfied the CLIA criteria of interchangeability for all tested parameters, except for hemoglobin. These results are warranted for our own procedures and devices. Bearing these restrictions, we recommend clinicians to initiate an appropriate therapy based on POC testing without awaiting a control measurement.

  2. Pontos críticos de controle de Salmonella spp. no abate de frangos Critical control points for Salmonella spp. in poultry slaughter

    Directory of Open Access Journals (Sweden)

    D.A.S. Von Rückert

    2009-04-01

    Full Text Available Avaliou-se a presença de Salmonella spp. em esfregaços superficiais em 135 carcaças de frangos, coletadas em cinco diferentes fases do abate, utilizando os métodos de microbiologia convencional, reação em cadeia de polimerase (PCR e imunoanálise. Os três métodos resultaram em tendência semelhante de detecção de Salmonella spp. nas carcaças de frango, ao longo da linha de abate. A maior frequência de Salmonella spp. foi determinada após o chuveiro de lavagem das carcaças, localizado entre a evisceração e o pré-resfriamento. Vinte (14,8% esfregaços foram determinados pela metodologia convencional, 52 (38,5% pela PCR e 66 (48,8% pela imunoanálise. A menor contaminação foi encontrada na saída do pré-resfriamento, com frequências de 3,7%, 0% e 16,7%, respectivamente. Salmonella spp. foi encontrada em todas as fases de abate, mostrando a importância do monitoramento de diferentes pontos críticos de controle eventualmente identificados no abate de frangos.The presence of Salmonella spp. in superficial swabs collected from 135 chicken carcasses in five different slaugther steps using the conventional microbiology, PCR, and immunoanalysis methods was evaluated. The three methods presented similar tendency to detect Salmonella spp. in the chicken carcasses along the slaugther line. The highest frequency of Salmonella spp. was found after the shower, located between the evisceration and the chiller. Twenty (14.8% swabes were determined by the conventional methodology, 52 (38.9% by the PCR, and 66 (48.9% by the immunoanalysis. The lowest contamination was found after chiller tank, where the frequencies were 5 (3.7%, 0 (0%, and 24 (16.7%, respectively. Salmonella spp. was found in all the slaugther steps. This shows the importance for monitoring different CCP (Control Critical Point in the poultry slaughterhouses.

  3. Contamination and Critical Control Points (CCPs along the processing line of sale of frozen poultry foods in retail outlets of a typical market in Ibadan, Nigeria

    Directory of Open Access Journals (Sweden)

    Adetunji, V. O

    2013-12-01

    Full Text Available Aim: Over the years, there have been considerable increases in the consumption of frozen poultry foods across Nigeria. Little attention has been paid to the microbial quality of these foods and hence constitutes a threat to public health. The contamination levels (Enterobacteriaceae and Listeria counts and the presence of pathogenic E. coli, Salmonella and Listeria along the processing line of sale of frozen poultry foods were assayed in retail outlets. Methodology and results: Bacteriological counts and bacterial isolation were carried out using standard plate methods, while the direct slide agglutination technique was utilized for serology. Bacteriological assay revealed extremely high counts (Listeria count (LC: 7.784±1.109 - 9.586±0.016 log cfu/cm2; Enterobacteriaceae count (EC: 7.151±0.213 - 9.318±0.161 log cfu/cm2, higher than stipulated by International Food Standard Agencies. The highest count for EC (9.318±0.161 log cfu/cm2 and LC 9.586±0.016 log cfu/cm2 was from the weighing scale and processing table. Averagely, LC (8.598±0.733 log cfu/cm2 was higher than EC (8.145±0.936 log cfu/cm2. Weighing scale had counts significantly different (p < 0.05 from all others for EC. But there were no significant differences in LC. Weighing scale and meat tables were critical control points (CCPs in the processing line for sale of frozen poultry meats in the retail outlets. E. coli spp., E. coli O157:H7, Salmonella spp., Salmonella Enteritidis, Listeria spp. and Listeria monocytogenes were isolated along the processing line. Conclusion, significance and impact of the study: Results of this study indicated that poultry meat are easily contaminated along the processing line of sale and may act as a potential risk to public health if counteractive measures are not applied to reduce microbial contamination during storage, sale and distribution to consumers.

  4. Point-of-Care Versus Central Laboratory Measurements of Hemoglobin, Hematocrit, Glucose, Bicarbonate and Electrolytes: A Prospective Observational Study in Critically Ill Patients.

    Science.gov (United States)

    Allardet-Servent, Jérôme; Lebsir, Melissa; Dubroca, Christian; Fabrigoule, Martine; Jordana, Sylvie; Signouret, Thomas; Castanier, Matthias; Thomas, Guillemette; Soundaravelou, Rettinavelou; Lepidi, Anne; Delapierre, Laurence; Penaranda, Guillaume; Halfon, Philippe; Seghboyan, Jean-Marie

    2017-01-01

    Rapid detection of abnormal biological values using point-of-care (POC) testing allows clinicians to promptly initiate therapy; however, there are concerns regarding the reliability of POC measurements. We investigated the agreement between the latest generation blood gas analyzer and central laboratory measurements of electrolytes, bicarbonate, hemoglobin, hematocrit, and glucose. 314 paired samples were collected prospectively from 51 critically ill patients. All samples were drawn simultaneously in the morning from an arterial line. BD Vacutainer tubes were analyzed in the central laboratory using Beckman Coulter analyzers (AU 5800 and DxH 800). BD Preset 3 ml heparinized-syringes were analyzed immediately in the ICU using the POC Siemens RAPIDPoint 500 blood gas system. We used CLIA proficiency testing criteria to define acceptable analytical performance and interchangeability. Biases, limits of agreement (±1.96 SD) and coefficients of correlation were respectively: 1.3 (-2.2 to 4.8 mmol/L, r = 0.936) for sodium; 0.2 (-0.2 to 0.6 mmol/L, r = 0.944) for potassium; -0.9 (-3.7 to 2 mmol/L, r = 0.967) for chloride; 0.8 (-1.9 to 3.4 mmol/L, r = 0.968) for bicarbonate; -11 (-30 to 9 mg/dL, r = 0.972) for glucose; -0.8 (-1.4 to -0.2 g/dL, r = 0.985) for hemoglobin; and -1.1 (-2.9 to 0.7%, r = 0.981) for hematocrit. All differences were below CLIA cut-off values, except for hemoglobin. Compared to central Laboratory analyzers, the POC Siemens RAPIDPoint 500 blood gas system satisfied the CLIA criteria of interchangeability for all tested parameters, except for hemoglobin. These results are warranted for our own procedures and devices. Bearing these restrictions, we recommend clinicians to initiate an appropriate therapy based on POC testing without awaiting a control measurement.

  5. Complement pathway biomarkers and age-related macular degeneration

    Science.gov (United States)

    Gemenetzi, M; Lotery, A J

    2016-01-01

    In the age-related macular degeneration (AMD) ‘inflammation model', local inflammation plus complement activation contributes to the pathogenesis and progression of the disease. Multiple genetic associations have now been established correlating the risk of development or progression of AMD. Stratifying patients by their AMD genetic profile may facilitate future AMD therapeutic trials resulting in meaningful clinical trial end points with smaller sample sizes and study duration. PMID:26493033

  6. GIS-based landslide hazard evaluation at the regional scale: some critical points in the permanent displacement approach for seismically-induced landslide maps

    Science.gov (United States)

    Vessia, Giovanna; Parise, Mario

    2013-04-01

    the assumed depth of the sliding surface. Thus, it is of paramount relevance to correctly understand and describe the dynamic behavior of the lithologies affected by the earthquake. Accordingly, we put here in evidence some critical points in the application of the permanent displacement formulations by considering the case study of Santa Susana Mountains (California, USA) shaken by the Northridge earthquake in 1994. During this earthquake, a high number of registrations has been collected, whilst soon after a careful inventory of the mass movements triggered by the shaking has been produced, together with analysis of the related failure mechanisms. Hence, these data allow to perform a back analysis in order to verify the reliability of some numerical expressions, such as those proposed by Ambraseys and Menu (1988), Romeo (2000), and Jibson (2007), with respect to the possible dynamic behavior of the lithologies affected by landslides. In this sector of California, the following lithologies crop out, that were involved in shallow landslides: (1) Quaternay deposits; (2) Saugus Formation; (3) Towsley Formation; (4) Pico Formation; (5) Topanga Formation; (6) Modelo Formation; (7) Simi Conglomerate; (8) Santa Susana Formation; (9) Llajas and Chatsworth Formations. The surveys carried out after the Northridge earthquake (Harp and Jibson, 1995), and the analysis of landslide distribution (Parise and Jibson 2000) pointed out that the strongest formations with slopes higher than 50° mainly suffered toppling or fall failures: thus, our hazard maps based on permanent displacements did not take into account such range of slopes. Further, areas with slopes lower than 10° were not affected by relevant mass movements. Thus, a limited range of slopes (between 10° and 45°) was considered in the analyses, with depth of the sliding surface varying between 1 and 3 m, and using the resistance parameters of involved lithologies obtained from in situ and laboratory tests performed by

  7. Disc degeneration: current surgical options

    Directory of Open Access Journals (Sweden)

    C Schizas

    2010-10-01

    Full Text Available Chronic low back pain attributed to lumbar disc degeneration poses a serious challenge to physicians. Surgery may be indicated in selected cases following failure of appropriate conservative treatment. For decades, the only surgical option has been spinal fusion, but its results have been inconsistent. Some prospective trials show superiority over usual conservative measures while others fail to demonstrate its advantages. In an effort to improve results of fusion and to decrease the incidence of adjacent segment degeneration, total disc replacement techniques have been introduced and studied extensively. Short-term results have shown superiority over some fusion techniques. Mid-term results however tend to show that this approach yields results equivalent to those of spinal fusion. Nucleus replacement has gained some popularity initially, but evidence on its efficacy is scarce. Dynamic stabilisation, a technique involving less rigid implants than in spinal fusion and performed without the need for bone grafting, represents another surgical option. Evidence again is lacking on its superiority over other surgical strategies and conservative measures. Insertion of interspinous devices posteriorly, aiming at redistributing loads and relieving pain, has been used as an adjunct to disc removal surgery for disc herniation. To date however, there is no clear evidence on their efficacy. Minimally invasive intradiscal thermocoagulation techniques have also been tried, but evidence of their effectiveness is questioned. Surgery using novel biological solutions may be the future of discogenic pain treatment. Collaboration between clinicians and basic scientists in this multidisciplinary field will undoubtedly shape the future of treating symptomatic disc degeneration.

  8. Lattice degeneration of the retina.

    Science.gov (United States)

    Byer, N E

    1979-01-01

    Lattice degeneration of the retina is the most important of all clinically distinct entities that effect the peripheral fundus and are related to retinal detachment. The purpose of this review is to survey the extensive literature, to evaluate the many diverse opinions on this subject, and to correlate and summarize all the known facts regarding this disease entity. The disease is fully defined and described, both clinically and histologically. Some aspects of the disease are still poorly understood, and some remain controversial, especially in the area of management. For this reason, the indications for treatment are discussed under eight subsections, with a view toward providing practical guidelines for recommendations in management.

  9. Age-related macular degeneration

    DEFF Research Database (Denmark)

    la Cour, Morten; Kiilgaard, Jens Folke; Nissen, Mogens Holst

    2002-01-01

    Age-related macular degeneration (AMD) is a common macular disease affecting elderly people in the Western world. It is characterised by the appearance of drusen in the macula, accompanied by choroidal neovascularisation (CNV) or geographic atrophy. The disease is more common in Caucasian....... Smoking is probably also a risk factor. Preventive strategies using macular laser photocoagulation are under investigation, but their efficacy in preventing visual loss is as yet unproven. There is no treatment with proven efficacy for geographic atrophy. Optimal treatment for exudative AMD requires...

  10. Relationship between full-thickness macular hole and retinal break/lattice degeneration.

    Science.gov (United States)

    Zhang, Jinglin; Li, Yonghao; Zhao, Xiujuan; Cai, Yu; Yu, Xiling; Lu, Lin

    2015-12-01

    The purpose is to investigate the relationship between full-thickness macular hole (MH) and retinal break (RB) and/or lattice degeneration. Patients diagnosed as full-thickness MH and referred to Dr. Lin Lu from January 2009 to December 2013 were evaluated. All patients underwent general ophthalmologic examinations, fundus examination and optical coherence tomography (OCT). The RB and/or lattice degeneration were recorded. Totally 183 eyes of 167 patients were included. The sex ratio of men to women was 1:2.88. A total of 17 eyes were pseudophakic and 166 eyes were phakic. RB and/or lattice degeneration were found in 62 eyes (33.88%). The prevalence of RB and/or lattice degeneration was similar between men and women (P = 0.344 > 0.05). There was no statistical difference between the pseudophakic eyes and phakic eyes (P = 0.138 > 0.05). All of the RB and/or lattice degeneration were located near or anterior to the equator. The inferior quadrants and the vertical meridian were affected more often than the superior quadrants and the horizontal meridian. We identified a high incidence of RB/lattice degeneration in cases of full-thickness MH. Carefully examination of the peripheral retina and prophylactic treatment of RB and/or lattice degeneration are critical.

  11. PHOTODYNAMIC THERAPY OF MACULAR DEGENERATION

    Directory of Open Access Journals (Sweden)

    Davorin Sevšek

    2004-05-01

    Full Text Available Background. University Eye Clinic in Ljubljana began to perform a photodynamic therapy (PDT in July 2002. Up to September 2003 there were 51 PDT interventions on 36 eyes. Almost half of the eyes had one or more reinterventions. PDT was used on 29 eyes with age related macular degeneration (AMD. Just before the treatment all of them had visual acuity (VA 6/60 or better and there were predominantly classical or classical choroidal neovascular (CNV membranes. Most VA did not changed significantly in follow-up visits but diameter of CNV membranes was obviously reduced. In macular degeneration due to pathologic myopia (MMD, photodynamic therapy was performed on 7 eyes with mainly occult CNV and VA was 12/60 or better. VA was mostly better in follow-up visits than before treatment with PDT.Conclusions. There were no serious complications during and after PDT interventions. Two patients had back pain during the infusion of Verteporfin but there was no need to stop the intervention.

  12. Age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Querques G

    2011-05-01

    Full Text Available Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris-Est Créteil, Créteil, France; ²Parma Eye Clinic University Hospital, Università degli Studi di Parma, Parma, Italy; ³Department of Ophthalmology, Università Vita-Salute San Raffaele Milano, Milano, Italy Date of preparation: March 3, 2011 Conflict of interest: None declaredClinical question: Is there any new knowledge about the pathogenesis and treatment of age-related macular degeneration (AMD?Results: We now understand better the biochemical and pathological pathways involved in the genesis of AMD. Treatment of exudative AMD is based on intravitreal injection of new antivascular endothelial growth factor drugs for which there does not yet exist a unique recognized strategy of administration. No therapies are actually available for atrophic AMD, despite some experimental new pharmacological approaches.Implementation: strategy of administration, safety of intravitreal injectionKeywords: age-related macular degeneration, antivascular endothelial growth factor, choroidal neovascularization, drusen, geographic atrophy

  13. Imaging of corticobasal degeneration syndrome

    International Nuclear Information System (INIS)

    Koyama, Masamichi; Yagishita, Akira; Nakata, Yasuhiro; Hayashi, Masaharu; Bandoh, Mitsuaki; Mizutani, Toshio

    2007-01-01

    Diagnosing corticobasal degeneration is often difficult on the basis of clinical symptoms and radiological images. We aimed to clarify the imaging findings of corticobasal degeneration syndrome (CBDS). Included in the study were 16 patients (8 men, 8 women, 46-75 years old) with clinically diagnosed CBDS. We evaluated the patients' symptoms and signs, and MR and single-photon emission CT (SPECT) imaging findings. All the patients had cerebral atrophy. Asymmetric cerebral atrophy was observed in 13 patients (81%) predominantly contralateral to the side clinically more affected. Atrophy in the cerebral peduncle was observed in seven patients. FLAIR images showed hyperintensity in the subcortical white matter in the frontoparietal lobes in the clinically more affected side in 14 patients, and in the rolandic region in 13 patients. Asymmetric hypoperfusion in the frontoparietal lobes on SPECT images was observed in all of the patients, and in the basal ganglia in 11 patients. CBDS might be unique in showing hyperintensity in the subcortical white matter in the rolandic region on FLAIR images with asymmetric atrophy predominantly contralateral to the side clinically more severely affected. Asymmetric atrophy in the cerebral peduncle without signal abnormalities was also characteristic of CBDS. Atrophy in the midbrain tegmentum was also seen in patients with CBDS. (orig.)

  14. Mitigation of Critical Single Point Failure (SPF) Material - Laminac 4116 Binder Replacement Program for Parachute and Cluster Stars Illuminant Compositions for Hand Held Signals

    National Research Council Canada - National Science Library

    Lakshminarayanan, G. R; Chen, Gary; Ames, Richard; Lee, Wai T; Wejsa, James L

    2006-01-01

    Laminac 4116 binder has been identified as a single point failure (SPF) material since it is being produced by only one company and there is a possibility that the company may discontinue production due to low product demand...

  15. Evolution of Quantum Fluctuations Near the Quantum Critical Point of the Transverse Field Ising Chain System CoNb_{2}O_{6}

    Directory of Open Access Journals (Sweden)

    A. W. Kinross

    2014-07-01

    Full Text Available The transverse field Ising chain model is ideally suited for testing the fundamental ideas of quantum phase transitions because its well-known T=0 ground state can be extrapolated to finite temperatures. Nonetheless, the lack of appropriate model materials hindered the past effort to test the theoretical predictions. Here, we map the evolution of quantum fluctuations in the transverse field Ising chain based on nuclear magnetic resonance measurements of CoNb_{2}O_{6}, and we demonstrate the finite-temperature effects on quantum criticality for the first time. From the temperature dependence of the ^{93}Nb longitudinal relaxation rate 1/T_{1}, we identify the renormalized classical, quantum critical, and quantum disordered scaling regimes in the temperature (T vs transverse magnetic field (h_{⊥} phase diagram. Precisely at the critical field h_{⊥}^{c}=5.25±0.15  T, we observe a power-law behavior, 1/T_{1}∼T^{−3/4}, as predicted by quantum critical scaling. Our parameter-free comparison between the data and theory reveals that quantum fluctuations persist up to as high as T∼0.4J, where the intrachain exchange interaction J is the only energy scale of the problem.

  16. Identifying Initial Condition in Degenerate Parabolic Equation with Singular Potential

    Directory of Open Access Journals (Sweden)

    K. Atifi

    2017-01-01

    Full Text Available A hybrid algorithm and regularization method are proposed, for the first time, to solve the one-dimensional degenerate inverse heat conduction problem to estimate the initial temperature distribution from point measurements. The evolution of the heat is given by a degenerate parabolic equation with singular potential. This problem can be formulated in a least-squares framework, an iterative procedure which minimizes the difference between the given measurements and the value at sensor locations of a reconstructed field. The mathematical model leads to a nonconvex minimization problem. To solve it, we prove the existence of at least one solution of problem and we propose two approaches: the first is based on a Tikhonov regularization, while the second approach is based on a hybrid genetic algorithm (married genetic with descent method type gradient. Some numerical experiments are given.

  17. Inflammatory profiles in canine intervertebral disc degeneration

    NARCIS (Netherlands)

    Willems, Nicole; Tellegen, Anna R; Bergknut, Niklas; Creemers, Laura B; Wolfswinkel, Jeannette; Freudigmann, Christian; Benz, Karin; Grinwis, Guy C M; Tryfonidou, Marianna A; Meij, Björn P

    2016-01-01

    BACKGROUND: Intervertebral disc (IVD) disease is a common spinal disorder in dogs and degeneration and inflammation are significant components of the pathological cascade. Only limited studies have studied the cytokine and chemokine profiles in IVD degeneration in dogs, and mainly focused on gene

  18. Genetic association studies in lumbar disc degeneration

    DEFF Research Database (Denmark)

    Eskola, Pasi J; Lemmelä, Susanna; Kjaer, Per

    2012-01-01

    Low back pain is associated with lumbar disc degeneration, which is mainly due to genetic predisposition. The objective of this study was to perform a systematic review to evaluate genetic association studies in lumbar disc degeneration as defined on magnetic resonance imaging (MRI) in humans....

  19. Naturalness of nearly degenerate neutrinos

    CERN Document Server

    Casas, J A; Ibarra, Alejandro; Navarro, I

    1999-01-01

    If neutrinos are to play a relevant cosmological role, they must be essentially degenerate. We study whether radiative corrections can or cannot be responsible for the small mass splittings, in agreement with all the available experimental data. We perform an exhaustive exploration of the bimaximal mixing scenario, finding that (i) the vacuum oscillations solution to the solar neutrino problem is always excluded; (ii) if the mass matrix is produced by a see-saw mechanism, there are large regions of the parameter space consistent with the large angle MSW solution, providing a natural origin for the Delta m^2_{sol} << Delta m^2_{atm} hierarchy; (iii) the bimaximal structure becomes then stable under radiative corrections. We also provide analytical expressions for the mass splittings and mixing angles and present a particularly simple see-saw ansatz consistent with all the observations.

  20. Age-related macular degeneration

    DEFF Research Database (Denmark)

    la Cour, Morten; Kiilgaard, Jens Folke; Nissen, Mogens Holst

    2002-01-01

    cause of blindness among Caucasian individuals in developed countries. Blindness resulting from AMD rarely occurs before age 70, and most cases occur after age 80. The age-standardised 1-year incidence of legal blindness resulting from AMD is 212 cases per million. Two-thirds of AMD cases have CNV......Age-related macular degeneration (AMD) is a common macular disease affecting elderly people in the Western world. It is characterised by the appearance of drusen in the macula, accompanied by choroidal neovascularisation (CNV) or geographic atrophy. The disease is more common in Caucasian...... individuals than in pigmented races. In predominantly Caucasian populations, the age-standardised prevalence of AMD in at least one eye is 7760 cases per million. The age-standardised cumulated 1-year incidence of AMD in at least one eye is 1051 cases per million individuals. AMD is the most important single...

  1. Regularized linearization for quantum nonlinear optical cavities: application to degenerate optical parametric oscillators.

    Science.gov (United States)

    Navarrete-Benlloch, Carlos; Roldán, Eugenio; Chang, Yue; Shi, Tao

    2014-10-06

    Nonlinear optical cavities are crucial both in classical and quantum optics; in particular, nowadays optical parametric oscillators are one of the most versatile and tunable sources of coherent light, as well as the sources of the highest quality quantum-correlated light in the continuous variable regime. Being nonlinear systems, they can be driven through critical points in which a solution ceases to exist in favour of a new one, and it is close to these points where quantum correlations are the strongest. The simplest description of such systems consists in writing the quantum fields as the classical part plus some quantum fluctuations, linearizing then the dynamical equations with respect to the latter; however, such an approach breaks down close to critical points, where it provides unphysical predictions such as infinite photon numbers. On the other hand, techniques going beyond the simple linear description become too complicated especially regarding the evaluation of two-time correlators, which are of major importance to compute observables outside the cavity. In this article we provide a regularized linear description of nonlinear cavities, that is, a linearization procedure yielding physical results, taking the degenerate optical parametric oscillator as the guiding example. The method, which we call self-consistent linearization, is shown to be equivalent to a general Gaussian ansatz for the state of the system, and we compare its predictions with those obtained with available exact (or quasi-exact) methods. Apart from its operational value, we believe that our work is valuable also from a fundamental point of view, especially in connection to the question of how far linearized or Gaussian theories can be pushed to describe nonlinear dissipative systems which have access to non-Gaussian states.

  2. Degeneration of Bethe subalgebras in the Yangian of gl_n

    Science.gov (United States)

    Ilin, Aleksei; Rybnikov, Leonid

    2018-04-01

    We study degenerations of Bethe subalgebras B( C) in the Yangian Y(gl_n), where C is a regular diagonal matrix. We show that closure of the parameter space of the family of Bethe subalgebras, which parameterizes all possible degenerations, is the Deligne-Mumford moduli space of stable rational curves \\overline{M_{0,n+2}}. All subalgebras corresponding to the points of \\overline{M_{0,n+2}} are free and maximal commutative. We describe explicitly the "simplest" degenerations and show that every degeneration is the composition of the simplest ones. The Deligne-Mumford space \\overline{M_{0,n+2}} generalizes to other root systems as some De Concini-Procesi resolution of some toric variety. We state a conjecture generalizing our results to Bethe subalgebras in the Yangian of arbitrary simple Lie algebra in terms of this De Concini-Procesi resolution.

  3. On the long wavelength thermodynamic limit of a neutron diffraction experiment in the vicinity of a liquid-liquid critical point. Application to the concentration fluctuations in the Li-ND3 system

    International Nuclear Information System (INIS)

    Chieux, P.; Damay, P.

    1978-01-01

    A quantitative comparison is made between the thermodynamics as obtained from the long wavelength limit of a small angle neutron scattering experiment in the vicinity of a liquid-liquid critical point for the Li-ND 3 system and the data obtained from vapour pressure measurements. The agreement is fair. It is shown how the comparison always implies an underlying model of the interacting species leading to the liquid-liquid phase separation. (Auth.)

  4. On the triviality of lambdaphi4sub(d) theories and the approach to the critical point in d >(>=) 4 dimensions

    International Nuclear Information System (INIS)

    Froehlich, J.

    1982-01-01

    It is shown that one- and two-component lambda vertical stroke phi vertical stroke 4 theories and non-linear sigma-models in five or more dimensions approach free or generalized free fields in the continuum (scaling) limit, and that in four dimensions the same result holds, provided there is infinite field strength renormalization, as expected. Some critical exponents for the lattice theories in five or more dimensions are shown to be mean field. The main tools are Symanzik's polymer representation of scalar field theories and correlation inequalities. (orig.)

  5. Age related macular degeneration and visual disability.

    Science.gov (United States)

    Christoforidis, John B; Tecce, Nicola; Dell'Omo, Roberto; Mastropasqua, Rodolfo; Verolino, Marco; Costagliola, Ciro

    2011-02-01

    Age-related macular degeneration (AMD) is the leading cause of central blindness or low vision among the elderly in industrialized countries. AMD is caused by a combination of genetic and environmental factors. Among modifiable environmental risk factors, cigarette smoking has been associated with both the dry and wet forms of AMD and may increase the likelihood of worsening pre-existing AMD. Despite advances, the treatment of AMD has limitations and affected patients are often referred for low vision rehabilitation to help them cope with their remaining eyesight. The characteristic visual impairment for both forms of AMD is loss of central vision (central scotoma). This loss results in severe difficulties with reading that may be only partly compensated by magnifying glasses or screen-projection devices. The loss of central vision associated with the disease has a profound impact on patient quality of life. With progressive central visual loss, patients lose their ability to perform the more complex activities of daily living. Common vision aids include low vision filters, magnifiers, telescopes and electronic aids. Low vision rehabilitation (LVR) is a new subspecialty emerging from the traditional fields of ophthalmology, optometry, occupational therapy, and sociology, with an ever-increasing impact on the usual concepts of research, education, and services for visually impaired patients. Relatively few ophthalmologists practise LVR and fewer still routinely use prismatic image relocation (IR) in AMD patients. IR is a method of stabilizing oculomotor functions with the purpose of promoting better function of preferred retinal loci (PRLs). The aim of vision rehabilitation therapy consists in the achievement of techniques designed to improve PRL usage. The use of PRLs to compensate for diseased foveae has offered hope to these patients in regaining some function. However, in a recently published meta-analysis, prism spectacles were found to be unlikely to be of

  6. Axon degeneration: make the Schwann cell great again

    Directory of Open Access Journals (Sweden)

    Keit Men Wong

    2017-01-01

    Full Text Available Axonal degeneration is a pivotal feature of many neurodegenerative conditions and substantially accounts for neurological morbidity. A widely used experimental model to study the mechanisms of axonal degeneration is Wallerian degeneration (WD, which occurs after acute axonal injury. In the peripheral nervous system (PNS, WD is characterized by swift dismantling and clearance of injured axons with their myelin sheaths. This is a prerequisite for successful axonal regeneration. In the central nervous system (CNS, WD is much slower, which significantly contributes to failed axonal regeneration. Although it is well-documented that Schwann cells (SCs have a critical role in the regenerative potential of the PNS, to date we have only scarce knowledge as to how SCs 'sense' axonal injury and immediately respond to it. In this regard, it remains unknown as to whether SCs play the role of a passive bystander or an active director during the execution of the highly orchestrated disintegration program of axons. Older reports, together with more recent studies, suggest that SCs mount dynamic injury responses minutes after axonal injury, long before axonal breakdown occurs. The swift SC response to axonal injury could play either a pro-degenerative role, or alternatively a supportive role, to the integrity of distressed axons that have not yet committed to degenerate. Indeed, supporting the latter concept, recent findings in a chronic PNS neurodegeneration model indicate that deactivation of a key molecule promoting SC injury responses exacerbates axonal loss. If this holds true in a broader spectrum of conditions, it may provide the grounds for the development of new glia-centric therapeutic approaches to counteract axonal loss.

  7. Preparing a highly degenerate Fermi gas in an optical lattice

    International Nuclear Information System (INIS)

    Williams, J. R.; Huckans, J. H.; Stites, R. W.; Hazlett, E. L.; O'Hara, K. M.

    2010-01-01

    We propose a method to prepare fermionic atoms in a three-dimensional optical lattice at unprecedentedly low temperatures and uniform filling factors. The process involves adiabatic loading of degenerate atoms into multiple energy bands of an optical lattice followed by a filtering stage whereby atoms from all but the lowest band are removed. Of critical importance is the use of a nonharmonic trapping potential to provide external confinement for the atoms. For realistic experimental parameters, this procedure will produce a Fermi gas in a lattice with a reduced temperature T/T F ∼0.003 and an entropy per particle of s∼0.02 k B .

  8. Characterizing degenerate Sturm-Liouville problems

    Directory of Open Access Journals (Sweden)

    Angelo B. Mingarelli

    2004-11-01

    Full Text Available Consider the Dirichlet eigenvalue problem associated with the real two-term weighted Sturm-Liouville equation $$-(p(xy'' = lambda r(xy$$ on the finite interval [a,b]. This eigenvalue problem will be called degenerate provided its spectrum fills the whole complex plane. Generally, in degenerate cases the coefficients $p(x, r(x$ must each be sign indefinite on [a,b]. Indeed, except in some special cases, the quadratic forms induced by them on appropriate spaces must also be indefinite. In this note we present a necessary and sufficient condition for this boundary problem to be degenerate. Some extensions are noted.

  9. Endophenotypes for Age-Related Macular Degeneration: Extending Our Reach into the Preclinical Stages of Disease.

    Science.gov (United States)

    Gorin, Michael B; Weeks, Daniel E; Baron, Robert V; Conley, Yvette P; Ortube, Maria C; Nusinowitz, Steven

    2014-11-28

    The key to reducing the individual and societal burden of age-related macular degeneration (AMD)-related vision loss, is to be able to initiate therapies that slow or halt the progression at a point that will yield the maximum benefit while minimizing personal risk and cost. There is a critical need to find clinical markers that, when combined with the specificity of genetic testing, will identify individuals at the earliest stages of AMD who would benefit from preventive therapies. These clinical markers are endophenotypes for AMD, present in those who are likely to develop AMD, as well as in those who have clinical evidence of AMD. Clinical characteristics associated with AMD may also be possible endophenotypes if they can be detected before or at the earliest stages of the condition, but we and others have shown that this may not always be valid. Several studies have suggested that dynamic changes in rhodopsin regeneration (dark adaptation kinetics and/or critical flicker fusion frequencies) may be more subtle indicators of AMD-associated early retinal dysfunction. One can test for the relevance of these measures using genetic risk profiles based on known genetic risk variants. These functional measures may improve the sensitivity and specificity of predictive models for AMD and may also serve to delineate clinical subtypes of AMD that may differ with respect to prognosis and treatment.

  10. Endophenotypes for Age-Related Macular Degeneration: Extending Our Reach into the Preclinical Stages of Disease

    Directory of Open Access Journals (Sweden)

    Michael B. Gorin

    2014-11-01

    Full Text Available The key to reducing the individual and societal burden of age-related macular degeneration (AMD-related vision loss, is to be able to initiate therapies that slow or halt the progression at a point that will yield the maximum benefit while minimizing personal risk and cost. There is a critical need to find clinical markers that, when combined with the specificity of genetic testing, will identify individuals at the earliest stages of AMD who would benefit from preventive therapies. These clinical markers are endophenotypes for AMD, present in those who are likely to develop AMD, as well as in those who have clinical evidence of AMD. Clinical characteristics associated with AMD may also be possible endophenotypes if they can be detected before or at the earliest stages of the condition, but we and others have shown that this may not always be valid. Several studies have suggested that dynamic changes in rhodopsin regeneration (dark adaptation kinetics and/or critical flicker fusion frequencies may be more subtle indicators of AMD-associated early retinal dysfunction. One can test for the relevance of these measures using genetic risk profiles based on known genetic risk variants. These functional measures may improve the sensitivity and specificity of predictive models for AMD and may also serve to delineate clinical subtypes of AMD that may differ with respect to prognosis and treatment.

  11. Analysis of Phakopsora pachyrhizi transcript abundance in critical pathways at four time-points during infection of a susceptible soybean cultivar using deep sequencing.

    Science.gov (United States)

    Tremblay, Arianne; Hosseini, Parsa; Li, Shuxian; Alkharouf, Nadim W; Matthews, Benjamin F

    2013-09-11

    Phakopsora pachyrhizi, the causal agent responsible for soybean rust, is among the top hundred most virulent plant pathogens and can cause soybean yield losses of up to 80% when appropriate conditions are met. We used mRNA-Seq by Illumina to analyze pathogen transcript abundance at 15 seconds (s), 7 hours (h), 48 h, and 10 days (d) after inoculation (ai) of susceptible soybean leaves with P. pachyrhizi to gain new insights into transcript abundance in soybean and the pathogen at specific time-points during the infection including the uredinial stage. Over three million five hundred thousand sequences were obtained for each time-point. Energy, nucleotide metabolism, and protein synthesis are major priorities for the fungus during infection and development as indicated by our transcript abundance studies. At all time-points, energy production is a necessity for P. pachyrhizi, as indicated by expression of many transcripts encoding enzymes involved in oxidative phosphorylation and carbohydrate metabolism (glycolysis, glyoxylate and dicarboxylate, pentose phosphate, pyruvate). However, at 15 sai, transcripts encoding enzymes involved in ATP production were highly abundant in order to provide enough energy for the spore to germinate, as observed by the expression of many transcripts encoding proteins involved in electron transport. At this early time-point, transcripts encoding proteins involved in RNA synthesis were also highly abundant, more so than transcripts encoding genes involved in DNA and protein synthesis. At 7 hai, shortly after germination during tube elongation and penetration, transcripts encoding enzymes involved in deoxyribonucleotide and DNA synthesis were highly abundant. At 48 hai, transcripts encoding enzymes involved in amino acid metabolism were highly abundant to provide for increased protein synthesis during haustoria maturation. During sporulation at 10 dai, the fungus still required carbohydrate metabolism, but there also was increased

  12. Mouse models for cone degeneration.

    Science.gov (United States)

    Samardzija, Marijana; Grimm, Christian

    2014-01-01

    Loss of cone vision has devastating effects on everyday life. Even though much effort has been made to understand cone physiology and pathophysiology, no successful therapies are available for patients suffering from cone disorders. As complex retinal interactions cannot be studied in vitro, utilization of different animal models is inevitable. Due to recent advances in transgenesis, mice became the most popular animal model to study human diseases, also in ophthalmology. While there are similarities in retinal anatomy and pathophysiology between mice and humans, there are also differences, most importantly the lack of a cone-rich macula in mice. Instead, cones in mice are rare and distributed over the whole retina, which makes the analysis of cone pathophysiology very difficult in these animals. This hindrance is one of the reasons why our understanding of rod pathophysiological processes is much more advanced. Recently, however, the sparseness of cones was overcome by the generation of the Nrl (- / -) mouse that expresses only cone photoreceptors in the retina. This paper will give a brief overview of some of the known mouse models to study cone degeneration and discuss the current knowledge gained from the analysis of these models.

  13. Degeneration of biogenic superparamagnetic magnetite.

    Science.gov (United States)

    Li, Y-L; Pfiffner, S M; Dyar, M D; Vali, H; Konhauser, K; Cole, D R; Rondinone, A J; Phelps, T J

    2009-01-01

    Magnetite crystals precipitated as a consequence of Fe(III) reduction by Shewanella algae BrY after 265 h incubation and 5-year anaerobic storage were investigated with transmission electron microscopy, Mössbauer spectroscopy and X-ray diffraction. The magnetite crystals were typically superparamagnetic with an approximate size of 13 nm. The lattice constants of the 265 h and 5-year crystals are 8.4164A and 8.3774A, respectively. The Mössbauer spectra indicated that the 265 h magnetite had excess Fe(II) in its crystal-chemistry (Fe(3+) (1.990)Fe(2+) (1.015)O(4)) but the 5-year magnetite was Fe(II)-deficient in stoichiometry (Fe(3+) (2.388)Fe(2+) (0.419)O(4)). Such crystal-chemical changes may be indicative of the degeneration of superparamagnetic magnetite through the aqueous oxidization of Fe(II) anaerobically, and the concomitant oxidation of the organic phases (fatty acid methyl esters) that were present during the initial formation of the magnetite. The observation of a corona structure on the aged magnetite corroborates the anaerobic oxidation of Fe(II) on the outer layers of magnetite crystals. These results suggest that there may be a possible link between the enzymatic activity of the bacteria and the stability of Fe(II)-excess magnetite, which may help explain why stable nano-magnetite grains are seldom preserved in natural environments.

  14. Degeneration of Biogenic Superparamagnetic Magnetite

    Energy Technology Data Exchange (ETDEWEB)

    Li, Dr. Yi-Liang [University of Tennessee, Knoxville (UTK); Pfiffner, Susan M. [University of Tennessee, Knoxville (UTK); Dyar, Dr. M Darby [Mount Holyoke College; Vali, Dr. Hojatolah [McGill University, Montreal, Quebec; Konhauser, Dr, Kurt [University of Alberta; Cole, David R [ORNL; Rondinone, Adam Justin [ORNL; Phelps, Tommy Joe [ORNL

    2009-01-01

    ABSTRACT. Magnetite crystals precipitated as a consequence of Fe(III) reduction by Shewanella algae BrY after 265 hours incubation and 5-year storage were investigated with transmission electron microscopy, M ssbauer spectroscopy and X-ray diffraction. The magnetite crystals were typically superparamagnetic with an approximate size of 13 nm. The lattice constants of the 265 hour and 5-year crystals are 8.4164 and 8.3774 , respectively. The M ssbauer spectra indicated that the 265 hour magnetite had excess Fe(II) in its crystal-chemistry (Fe3+1.9901Fe2+ 1.0149O4) but the 5-year magnetite was Fe(II)-deficient in stoichiometry (Fe3+2.3875Fe2+0.4188O4). Such crystal-hemical changes may be indicative of the degeneration of superparamagnetic magnetite through the aqueous oxidization of Fe(II) anaerobically, and the concomitant oxidation of the organic phases(fatty acid methyl esters) that were present during the initial formation of the magnetite. The observation of a corona structure on the aged magnetite corroborates the oxidation of Fe(II) on the outer layers of magnetite crystals. These results suggest that there may be a possible link between the enzymatic activity of the bacteria and the stability of Fe(II)-excess magnetite, which may help explain why stable nano-magnetite grains are seldom preserved in natural environments.

  15. Very Degenerate Higgsino Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Eung Jin [Korea Institute for Advanced Study,Seoul 130-722 (Korea, Republic of); Jung, Sunghoon [SLAC National Accelerator Laboratory,Menlo Park, CA 94025 (United States); Kavli Institute for Theoretical Physics,Santa Barbara, CA 93106 (United States); Park, Jong-Chul [Department of Physics, Chungnam National University,Daejeon 34134 (Korea, Republic of)

    2017-01-03

    We present a study of the Very Degenerate Higgsino Dark Matter (DM), whose mass splitting between the lightest neutral and charged components is O(1) MeV, much smaller than radiative splitting of 355 MeV. The scenario is realized in the minimal supersymmetric standard model by small gaugino mixings. In contrast to the pure Higgsino DM with the radiative splitting only, various observable signatures with distinct features are induced. First of all, the very small mass splitting makes (a) sizable Sommerfeld enhancement and Ramsauer-Townsend (RT) suppression relevant to ∼1 TeV Higgsino DM, and (b) Sommerfeld-Ramsauer-Townsend effect saturate at lower velocities v/c≲10{sup −3}. As a result, annihilation signals can be large enough to be observed from the galactic center and/or dwarf galaxies, while the relative signal sizes can vary depending on the locations of Sommerfeld peaks and RT dips. In addition, at collider experiments, stable chargino signatures can be searched for to probe the model in the future. DM direct detection signals, however, depend on the Wino mass; even no detectable signals can be induced if the Wino is heavier than about 10 TeV.

  16. Frustrated antiferromagnets at high fields: Bose-Einstein condensation in degenerate spectra

    International Nuclear Information System (INIS)

    Jackeli, G.; Zhitomirsky, M.E.

    2004-01-01

    Quantum phase transition at the saturation field is studied for a class of frustrated quantum antiferromagnets. The considered models include (i) the J 1 -J 2 frustrated square-lattice antiferromagnet with J 2 =(1/2)J 1 and (ii) the nearest-neighbor Heisenberg antiferromagnet on a face centered cubic lattice. In the fully saturated phase the magnon spectra for the two models have lines of degenerate minima. Transition into a partially magnetized state is treated via a mapping to a dilute gas of hard-core bosons and by complementary spin-wave calculations. Momentum dependence of the exact four-point boson vertex removes the degeneracy of the single-particle excitation spectra and selects the ordering wave vectors at (π,π) and (π,0,0) for the two models. We predict a unique form for the magnetization curve ΔM=S-M≅μ (d-1)/2 (logμ) (d-1) , where μ is a distance from the quantum critical point

  17. Magnetic resonance imaging of intervertebral disc degeneration

    International Nuclear Information System (INIS)

    Maeda, Hiroshi; Noguchi, Masao; Kira, Hideaki; Fujiki, Hiroshi; Shimokawa, Isao; Hinoue, Kaichi.

    1993-01-01

    The aim of this study was to correlate the degree of lumbar intervertebral disc degeneration with findings of magnetic resonance imaging (MRI). Seventeen autopsied (from 7 patients) and 21 surgical (from 20 patients) intervertebral discs were used as specimens for histopathological examination. In addition, 21 intervertebral discs were examined on T2-weighted images. Histopathological findings from both autopsied and surgical specimens were well correlated with MRI findings. In particular, T2-weighted images reflected increased collagen fibers and rupture within the fibrous ring accurately. However, when severely degenerated intervertebral discs and hernia protruding the posterior longitudinal ligament existed, histological findings were not concordant well with T2-weighted images. Morphological appearances of autopsy specimens, divided into four on T2-weighted images, were well consistent with histological degeneration. This morphological classification, as shown on T2-weighted images, could also be used in the evaluation of intervertebral disc degeneration. (N.K.)

  18. Magnetic resonance imaging of intervertebral disc degeneration

    Energy Technology Data Exchange (ETDEWEB)

    Maeda, Hiroshi; Noguchi, Masao (Kitakyushu City Yahata Hospital, Fukuoka (Japan)); Kira, Hideaki; Fujiki, Hiroshi; Shimokawa, Isao; Hinoue, Kaichi

    1993-02-01

    The aim of this study was to correlate the degree of lumbar intervertebral disc degeneration with findings of magnetic resonance imaging (MRI). Seventeen autopsied (from 7 patients) and 21 surgical (from 20 patients) intervertebral discs were used as specimens for histopathological examination. In addition, 21 intervertebral discs were examined on T2-weighted images. Histopathological findings from both autopsied and surgical specimens were well correlated with MRI findings. In particular, T2-weighted images reflected increased collagen fibers and rupture within the fibrous ring accurately. However, when severely degenerated intervertebral discs and hernia protruding the posterior longitudinal ligament existed, histological findings were not concordant well with T2-weighted images. Morphological appearances of autopsy specimens, divided into four on T2-weighted images, were well consistent with histological degeneration. This morphological classification, as shown on T2-weighted images, could also be used in the evaluation of intervertebral disc degeneration. (N.K.).

  19. Transport in the quantum critical regime

    Science.gov (United States)

    Enss, Tilman

    2014-05-01

    In this talk I will explain the relevance of the quantum critical point for the phase diagram of the unitary Fermi gas, briefly review theoretical approaches, and present results for the shear viscosity and spin diffusion in strongly interacting Fermi gases. The unitary Fermi gas describes strongly interacting fermions ranging from ultracold atoms near a Feshbach resonance to dilute neutron matter, which share a common universal phase diagram. The behavior at finite temperature is governed by a quantum critical point (QCP) at zero temperature and zero density, and observables can be expressed by universal scaling functions of the distance from the critical point. In the quantum critical regime above the QCP, thermal and quantum fluctuations are equally important, and the absence of a small parameter makes the computation of critical properties demanding. I will mention two theoretical approaches to transport properties in this regime: the large-N expansion in the number of fermion flavors allows for a systematic and controlled expansion even at strong coupling and elucidates the importance of medium effects on scattering. Second, the Luttinger-Ward, or self-consistent T-matrix approach goes beyond the quasiparticle picture and also explains universal high-energy tails. I will present results on the shear viscosity, or internal friction, for mass transport and show that the strongly interacting Fermi gas is an almost perfect quantum fluid. On the other hand, if particles of different spin move in opposite directions, the dynamics are governed by spin diffusion. One can distinguish longitudinal diffusion, when atomic clouds of different spin collide, and transverse diffusion, when the magnetization is wound up in a helix in a spin-echo experiment. Medium scattering and spin rotation have a strong effect on spin diffusion, and I will discuss how spin transport becomes very slow at strong coupling in the quantum degenerate regime and reaches a quantum limit of

  20. The nature of apraxia in corticobasal degeneration.

    OpenAIRE

    Leiguarda, R; Lees, A J; Merello, M; Starkstein, S; Marsden, C D

    1994-01-01

    Although apraxia is one of the most frequent signs in corticobasal degeneration, the phenomenology of this disorder has not been formally examined. Hence 10 patients with corticobasal degeneration were studied with a standardised evaluation for different types of apraxia. To minimise the confounding effects of the primary motor disorder, apraxia was assessed in the least affected limb. Whereas none of the patients showed buccofacial apraxia, seven showed deficits on tests of ideomotor apraxia...

  1. Myxomatous degeneration of the lumbar intervertebral disc.

    Science.gov (United States)

    Beatty, R A

    1985-08-01

    Sixteen patients were operated on for lumbar pain and pain radiating into the sciatic nerve distribution. In all 16, when the anulus fibrosus was incised, soft, gray disc material extruded under pressure like toothpaste being squeezed from a tube. This syndrome of myxomatous degeneration is a distinct entity, different from classical fibrotic disc degeneration or herniated nucleus pulposus. Surgical removal associated with partial facetectomy produced excellent results. The concept of incompetence of the anulus fibrosis is discussed.

  2. Hamiltonization of theories with degenerate coordinates

    International Nuclear Information System (INIS)

    Gitman, D.M.; Tyutin, I.V.

    2002-01-01

    We consider a class of Lagrangian theories where part of the coordinates does not have any time derivatives in the Lagrange function (we call such coordinates degenerate). We advocate that it is reasonable to reconsider the conventional definition of singularity based on the usual Hessian and, moreover, to simplify the conventional hamiltonization procedure. In particular, in such a procedure, it is not necessary to complete the degenerate coordinates with the corresponding conjugate momenta

  3. Solutions for correlations along the coexistence curve and at the critical point of a kagomé lattice gas with three-particle interactions

    Science.gov (United States)

    Barry, J. H.; Muttalib, K. A.; Tanaka, T.

    2008-01-01

    We consider a two-dimensional (d=2) kagomé lattice gas model with attractive three-particle interactions around each triangular face of the kagomé lattice. Exact solutions are obtained for multiparticle correlations along the liquid and vapor branches of the coexistence curve and at criticality. The correlation solutions are also determined along the continuation of the curvilinear diameter of the coexistence region into the disordered fluid region. The method generates a linear algebraic system of correlation identities with coefficients dependent only upon the interaction parameter. Using a priori knowledge of pertinent solutions for the density and elementary triplet correlation, one finds a closed and linearly independent set of correlation identities defined upon a spatially compact nine-site cluster of the kagomé lattice. Resulting exact solution curves of the correlations are plotted and discussed as functions of the temperature and are compared with corresponding results in a traditional kagomé lattice gas having nearest-neighbor pair interactions. An example of application for the multiparticle correlations is demonstrated in cavitation theory.

  4. Scaling behavior near the itinerant ferromagnetic quantum critical point (FQCP) of NiCoCrx for 0.8

    Science.gov (United States)

    Sales, Brian; Jin, Ke; Bei, Hongbin; Nichols, John; Chisholm, Matthew; May, Andrew; McGuire, Michael

    Low temperature magnetization, resistivity and heat capacity data are reported for the concentrated solid solution NiCoCrx as a function of temperature and magnetic field. In the quantum critical region the low field (0.001-0.01 T) magnetic susceptibility, Chi, diverges as T- 1 / 2 and the magnetization data exhibits T/B scaling from 0.001 2 Tesla, the crossover temperature from the QC to Fermi liquid regime is no longer linear in B, and is better described by B0.75. This scaling behavior is particularly accurate in describing the normalized magnetoresistance data [Rho(B,T)-Rho(0,T)]/T, which is equivalent to the ratio of relaxation rates associated with magnetic field and temperature TauT/TauB. The location of the QCP is sensitive to the composition x and the strain generated during synthesis. These medium-entropy alloys are interesting model systems to explore the role of chemical disorder at FQCP. Research supported by the DOE Office of Science, Materials Science and Engineering Division, and the Energy Dissipation to Defect Evolution EFRC.

  5. Asymptotic behavior of solutions to a degenerate quasilinear parabolic equation with a gradient term

    Directory of Open Access Journals (Sweden)

    Huilai Li

    2015-12-01

    Full Text Available This article concerns the asymptotic behavior of solutions to the Cauchy problem of a degenerate quasilinear parabolic equations with a gradient term. A blow-up theorem of Fujita type is established and the critical Fujita exponent is formulated by the spacial dimension and the behavior of the coefficient of the gradient term at infinity.

  6. Self-reported optometric practise patterns in age-related macular degeneration.

    Science.gov (United States)

    Ly, Angelica; Nivison-Smith, Lisa; Zangerl, Barbara; Assaad, Nagi; Kalloniatis, Michael

    2017-11-01

    The use of advanced imaging in clinical practice is emerging and the use of this technology by optometrists in assessing patients with age-related macular degeneration is of interest. Therefore, this study explored contemporary, self-reported patterns of practice regarding age-related macular degeneration diagnosis and management using a cross-sectional survey of optometrists in Australia and New Zealand. Practising optometrists were surveyed on four key areas, namely, demographics, clinical skills and experience, assessment and management of age-related macular degeneration. Questions pertaining to self-rated competency, knowledge and attitudes used a five-point Likert scale. Completed responses were received from 127 and 87 practising optometrists in Australia and New Zealand, respectively. Advanced imaging showed greater variation in service delivery than traditional techniques (such as slitlamp funduscopy) and trended toward optical coherence tomography, which was routinely performed in age-related macular degeneration by 49 per cent of respondents. Optical coherence tomography was also associated with higher self-rated competency, knowledge and perceived relevance to practice than other modalities. Most respondents (93 per cent) indicated that they regularly applied patient symptoms, case history, visual function results and signs from traditional testing, when queried about their management of patients with age-related macular degeneration. Over half (63 per cent) also considered advanced imaging, while 31 per cent additionally considered all of these as well as the disease stage and clinical guidelines. Contrary to the evidence base, 68 and 34 per cent rated nutritional supplements as highly relevant or relevant in early age-related macular degeneration and normal aging changes, respectively. These results highlight the emergence of multimodal and advanced imaging (especially optical coherence tomography) in the assessment of age-related macular degeneration

  7. A CRITICAL THOUGHT OF INSTRUCTIONAL STRATEGY: DEVELOPING ANALYTICAL CAPABILITY OF AUTOMOTIVE STUDENTS BY MANAGING MORE APPLICABLE MOVIE FRAGMENTS, POWER POINT, AND INTERACTIVE TEST

    Directory of Open Access Journals (Sweden)

    Agus Riyanto -

    2017-02-01

    Full Text Available What most sensed about Technical High School (known as SMK students is their lack of analytical capability. As their nature of academic orientation is aimed at job fullfillment, the students are enhanced to follow Standard Operational Procedure (SOP without questioning why such SOP should be followed. As for automotive students, they simply following the steps of doing things related to any activities of repairing car and other mechanical work required just because the job will be done well when the procedure completed.  This kind of mentality “following order or SOP” fits to those who only want to be workers not the men who take higher responsibilities. The progress of automotive technology demand on understanding the concept of how some system used in a car. Failure to comprehend to concept will jeopardize the performance of a car. At the same time, the progress of automotive technology is also propelled by the progress of information technology which provides more open resources that can be used to promote the quality of instuctional process.  Realizing that having analysis compentence is terribly important to run higher responsibilites and continuing education to a university, automotive students need to learn how to analyze. To promote this, teacher can use some automotive movies or animations and then chop them into many fragments related to instructional objectives. The way how the teachers arrange and present the fragments can be combined into power point and ended up with an interactive test with different model of methods, strategies, or techniques. Movies, movie cutter application, interactive test Creator ,  paint into fragments can be obtained freely from the internet. The using of movie fragments integrated into power point, arrange the fragment into various strategies, ended up with interactive test will likely focus the students into more realistic understanding toward the concept taught in the classroom. In return the

  8. 4f-derived Fermi surfaces of CeRu2(Si1-xGex)2 near the quantum critical point: resonant soft-X-ray ARPES study.

    Science.gov (United States)

    Okane, T; Ohkochi, T; Takeda, Y; Fujimori, S-i; Yasui, A; Saitoh, Y; Yamagami, H; Fujimori, A; Matsumoto, Y; Sugi, M; Kimura, N; Komatsubara, T; Aoki, H

    2009-05-29

    Angle-resolved photoelectron spectroscopy in the Ce 3d-->4f excitation region was measured for the paramagnetic state of CeRu2Si2, CeRu2(Si0.82Ge0.18)2, and LaRu2Si2 to investigate the changes of the 4f electron Fermi surfaces around the quantum critical point. While the difference of the Fermi surfaces between CeRu2Si2 and LaRu2Si2 was experimentally confirmed, a strong 4f-electron character was observed in the band structures and the Fermi surfaces of CeRu2Si2 and CeRu2(Si0.82Ge0.18)2, consequently indicating a delocalized nature of the 4f electrons in both compounds. The absence of Fermi surface reconstruction across the critical composition suggests that SDW quantum criticality is more appropriate than local quantum criticality in CeRu2(Si1-xGex)2.

  9. New signal acquisition and processing system for the execution of initial criticality after refueling and physical tests at low power in Angra-2, with the incorporation of the real time resolution of the inverse point kinetic equation - IPK

    Energy Technology Data Exchange (ETDEWEB)

    Júnior, Décio Brandes M.F.; Oliveira, Mônica Georgia N.; Silva, Cristiano da, E-mail: deciobr@eletronuclear.gov.br, E-mail: mongeor@eletronuclear.gov.br, E-mail: cdsilva@eletronuclear.gov.br [Eletrobrás Termonuclear S.A. (ELETRONUCLEAR), Angra dos Reis, RJ (Brazil). Departamento DDD.O - Física de Reatores

    2017-07-01

    The goal of this work is present the new System of Acquisition and Signal Processing for the execution of the initial criticality after refueling and physical tests at low power with the incorporation of the real time resolution of Inverse Point Kinetic Equations (IPK). The system was developed using cRIO 9082 hardware (compactRIO), which is a programmable logic controller (PLC) and, the National Lab's LabVIEW programming language. The developed system enabled a better visualization and monitoring interface of the neutron flux evolution during the first criticality of cycle and following the low power physical tests, which allows the Reactor Physics Group and Reactor Operators of Angra 2 guide faster and accurately the reactivity variations at physical tests. The digital reactivity meter developed reinforces in Angra-2 the set of operational practices of reactivity management. (author)

  10. New signal acquisition and processing system for the execution of initial criticality after refueling and physical tests at low power in Angra-2, with the incorporation of the real time resolution of the inverse point kinetic equation - IPK

    International Nuclear Information System (INIS)

    Júnior, Décio Brandes M.F.; Oliveira, Mônica Georgia N.; Silva, Cristiano da

    2017-01-01

    The goal of this work is present the new System of Acquisition and Signal Processing for the execution of the initial criticality after refueling and physical tests at low power with the incorporation of the real time resolution of Inverse Point Kinetic Equations (IPK). The system was developed using cRIO 9082 hardware (compactRIO), which is a programmable logic controller (PLC) and, the National Lab's LabVIEW programming language. The developed system enabled a better visualization and monitoring interface of the neutron flux evolution during the first criticality of cycle and following the low power physical tests, which allows the Reactor Physics Group and Reactor Operators of Angra 2 guide faster and accurately the reactivity variations at physical tests. The digital reactivity meter developed reinforces in Angra-2 the set of operational practices of reactivity management. (author)

  11. Use of the Neutron Activation Analysis, k0-standardized method, in the evaluation of the air quality in critical points of Belo Horizonte

    International Nuclear Information System (INIS)

    Moura, Igor Felipe S.; Cruz, Ananda B.; Cesar, Raisa H.S.; Oliveira, Aline F.G. de; Barreto, Alberto A.; Menezes, Maria Ângela de B.C.; Centro de Desenvolvimento da Tecnologia Nuclear

    2017-01-01

    Belo Horizonte, the capital of Minas Gerais, is one of the largest cities in Brazil. It is geographically centered on a region with intense mining and industrial activity and a fleet of more than 1.5 million vehicles. The numerous sources of atmospheric emissions of particulate matter in this capital and its vicinity offer a considerable risk to the degradation of air quality. In order to contribute with elemental composition of particulate matter, the Nuclear Technology Development Center / Brazilian Commission for Nuclear Energy, and the Department of Nuclear Engineering of the Federal University of Minas Gerais has developed a research based on environmental samples. This work aims to present the sampling methodology, the concentration values of sampled particulate matter, the methodology of analysis of elemental concentration using the nuclear technique of neutron activation analysis, k 0 -standardized method, and interpreted through statistical techniques and values of the elemental concentrations more representative of the samplings carried out. The results pointed out the vehicle emissions as the major source that contributes to airborne particulate matter followed by soil resuspension. (author)

  12. Use of the Neutron Activation Analysis, k0-standardized method, in the evaluation of the air quality in critical points of Belo Horizonte

    Energy Technology Data Exchange (ETDEWEB)

    Moura, Igor Felipe S.; Cruz, Ananda B.; Cesar, Raisa H.S.; Oliveira, Aline F.G. de; Barreto, Alberto A.; Menezes, Maria Ângela de B.C., E-mail: igorfelipedx@yahoo.com.br, E-mail: abc@cdtn.br, E-mail: raisa.santana@hotmail.com, E-mail: afgo@cdtn.br, E-mail: aab@cdtn.br, E-mail: menezes@cdtn.br [Universidade Federal de Minas Gerais (DEN/UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear; Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN), Belo Horizonte, MG (Brazil). Divisão de Meio Ambiente

    2017-07-01

    Belo Horizonte, the capital of Minas Gerais, is one of the largest cities in Brazil. It is geographically centered on a region with intense mining and industrial activity and a fleet of more than 1.5 million vehicles. The numerous sources of atmospheric emissions of particulate matter in this capital and its vicinity offer a considerable risk to the degradation of air quality. In order to contribute with elemental composition of particulate matter, the Nuclear Technology Development Center / Brazilian Commission for Nuclear Energy, and the Department of Nuclear Engineering of the Federal University of Minas Gerais has developed a research based on environmental samples. This work aims to present the sampling methodology, the concentration values of sampled particulate matter, the methodology of analysis of elemental concentration using the nuclear technique of neutron activation analysis, k{sub 0}-standardized method, and interpreted through statistical techniques and values of the elemental concentrations more representative of the samplings carried out. The results pointed out the vehicle emissions as the major source that contributes to airborne particulate matter followed by soil resuspension. (author)

  13. Serum levels of lipid metabolites in age-related macular degeneration

    OpenAIRE

    Orban, Tivadar; Johnson, William M.; Dong, Zhiqian; Maeda, Tadao; Maeda, Akiko; Sakai, Tsutomu; Tsuneoka, Hiroshi; Mieyal, John J.; Palczewski, Krzysztof

    2015-01-01

    Age-related macular degeneration (AMD) is a neurodegenerative disease that causes adult-onset blindness. There are 2 forms of this progressive disease: wet and dry. Currently there is no cure for AMD, but several treatment options have started to emerge making early detection critical for therapeutic success. Analysis of the eyes of Abca4−/−Rdh8−/− mice that display light-induced retinal degeneration indicates that 11-cis-retinal and docosahexaenoic acid (DHA) levels were significantly decrea...

  14. Lycium barbarum (wolfberry reduces secondary degeneration and oxidative stress, and inhibits JNK pathway in retina after partial optic nerve transection.

    Directory of Open Access Journals (Sweden)

    Hongying Li

    Full Text Available Our group has shown that the polysaccharides extracted from Lycium barbarum (LBP are neuroprotective for retinal ganglion cells (RGCs in different animal models. Protecting RGCs from secondary degeneration is a promising direction for therapy in glaucoma management. The complete optic nerve transection (CONT model can be used to study primary degeneration of RGCs, while the partial optic nerve transection (PONT model can be used to study secondary degeneration of RGCs because primary degeneration of RGCs and secondary degeneration can be separated in location in the same retina in this model; in other situations, these types of degeneration can be difficult to distinguish. In order to examine which kind of degeneration LBP could delay, both CONT and PONT models were used in this study. Rats were fed with LBP or vehicle daily from 7 days before surgery until sacrifice at different time-points and the surviving numbers of RGCs were evaluated. The expression of several proteins related to inflammation, oxidative stress, and the c-jun N-terminal kinase (JNK pathways were detected with Western-blot analysis. LBP did not delay primary degeneration of RGCs after either CONT or PONT, but it did delay secondary degeneration of RGCs after PONT. We found that LBP appeared to exert these protective effects by inhibiting oxidative stress and the JNK/c-jun pathway and by transiently increasing production of insulin-like growth factor-1 (IGF-1. This study suggests that LBP can delay secondary degeneration of RGCs and this effect may be linked to inhibition of oxidative stress and the JNK/c-jun pathway in the retina.

  15. Existence and Stability of Traveling Waves for Degenerate Reaction-Diffusion Equation with Time Delay

    Science.gov (United States)

    Huang, Rui; Jin, Chunhua; Mei, Ming; Yin, Jingxue

    2018-01-01

    This paper deals with the existence and stability of traveling wave solutions for a degenerate reaction-diffusion equation with time delay. The degeneracy of spatial diffusion together with the effect of time delay causes us the essential difficulty for the existence of the traveling waves and their stabilities. In order to treat this case, we first show the existence of smooth- and sharp-type traveling wave solutions in the case of c≥c^* for the degenerate reaction-diffusion equation without delay, where c^*>0 is the critical wave speed of smooth traveling waves. Then, as a small perturbation, we obtain the existence of the smooth non-critical traveling waves for the degenerate diffusion equation with small time delay τ >0 . Furthermore, we prove the global existence and uniqueness of C^{α ,β } -solution to the time-delayed degenerate reaction-diffusion equation via compactness analysis. Finally, by the weighted energy method, we prove that the smooth non-critical traveling wave is globally stable in the weighted L^1 -space. The exponential convergence rate is also derived.

  16. DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic.

    Science.gov (United States)

    Roberts, Jason A; De Waele, Jan J; Dimopoulos, George; Koulenti, Despoina; Martin, Claude; Montravers, Philippe; Rello, Jordi; Rhodes, Andrew; Starr, Therese; Wallis, Steven C; Lipman, Jeffrey

    2012-07-06

    The clinical effects of varying pharmacokinetic exposures of antibiotics (antibacterials and antifungals) on outcome in infected critically ill patients are poorly described. A large-scale multi-centre study (DALI Study) is currently underway describing the clinical outcomes of patients achieving pre-defined antibiotic exposures. This report describes the protocol. DALI will recruit over 500 patients administered a wide range of either beta-lactam or glycopeptide antibiotics or triazole or echinocandin antifungals in a pharmacokinetic point-prevalence study. It is anticipated that over 60 European intensive care units (ICUs) will participate. The primary aim will be to determine whether contemporary antibiotic dosing for critically ill patients achieves plasma concentrations associated with maximal activity. Secondary aims will compare antibiotic pharmacokinetic exposures with patient outcome and will describe the population pharmacokinetics of the antibiotics included. Various subgroup analyses will be conducted to determine patient groups that may be at risk of very low or very high concentrations of antibiotics. The DALI study should inform clinicians of the potential clinical advantages of achieving certain antibiotic pharmacokinetic exposures in infected critically ill patients.

  17. Linearly coupled oscillations in fully degenerate pair and warm pair-ion astrophysical plasmas

    Science.gov (United States)

    Khan, S. A.; Ilyas, M.; Wazir, Z.; Ehsan, Zahida

    2014-08-01

    In this paper we study the coexisting low frequency oscillations in strongly degenerate, magnetized, (electron-positron) pair and warm pair-ion plasma. The dispersion relations are obtained for both the cases in macroscopic quantum hydrodynamics approximation. In pair-ion case, the dispersion equation shows coupling of electrostatic and (shear) electromagnetic modes under certain circumstances with important role of ion temperature. Domain of existence of such waves and their relevance to dense degenerate astrophysical plasmas is pointed out. Results are analyzed numerically for typical systems with variation of ion concentration and ion temperature.

  18. [Peripheral retinal degenerations--treatment recommendations].

    Science.gov (United States)

    Joussen, A M; Kirchhof, B

    2004-10-01

    This report reviews the clinical appearance of degenerative diseases of the peripheral retina in relationship to the risk of developing a rhegmatogenous retinal detachment. We present recommendations for preventive treatment in eyes at increased risk of developing retinal detachment. Retinal degenerations are common lesions involving the peripheral retina but most of them are clinically insignificant. Lattice degeneration, degenerative retinoschisis, cystic retinal tufts, and very rarely zonular traction tufts can result in rhegmatogenous retinal detachment. Therefore, these lesions have been considered for prophylactic treatment; however, adequate studies have not been performed to date. Most of the peripheral retinal degenerations may not require treatment except in rare, high-risk situations. According to current knowledge there is no higher incidence of secondary pucker or other side effects after laser coagulation. Therefore, generous laser indication is recommended if risk factors apply.

  19. Families and degenerations of conformal field theories

    Energy Technology Data Exchange (ETDEWEB)

    Roggenkamp, D.

    2004-09-01

    In this work, moduli spaces of conformal field theories are investigated. In the first part, moduli spaces corresponding to current-current deformation of conformal field theories are constructed explicitly. For WZW models, they are described in detail, and sigma model realizations of the deformed WZW models are presented. The second part is devoted to the study of boundaries of moduli spaces of conformal field theories. For this purpose a notion of convergence of families of conformal field theories is introduced, which admits certain degenerated conformal field theories to occur as limits. To such a degeneration of conformal field theories, a degeneration of metric spaces together with additional geometric structures can be associated, which give rise to a geometric interpretation. Boundaries of moduli spaces of toroidal conformal field theories, orbifolds thereof and WZW models are analyzed. Furthermore, also the limit of the discrete family of Virasoro minimal models is investigated. (orig.)

  20. Intramuscular degeneration process in Duchenne muscular dystrophy

    International Nuclear Information System (INIS)

    Hasegawa, Takeshi; Matsumra, Kiichiro; Hashimoto, Takahiro; Ikehira, Hiroo; Fukuda, Hiroshi; Tateno, Yukio.

    1992-01-01

    Intramuscular degeneration process of Duchenne dystrophy skeletal muscles was investigated by longitudinal skeletal muscle imaging with high-field-strength NMR-CT of 1.5 Tesla. Thigh muscles in 10 cases ranging in age from 4 to 19 years were examined by T 1 -weighted longitudinal images (TR=215∼505 ms, TE=19∼20 ms). The following results were obtained. Skeletal muscle degeneration was depicted as high signal intensity area reflecting its high fat contents. These high signal intensity areas had a longitudinally streaky appearance in parallel direction with myofibers. These findings were more prominent toward myotendon junction than muscle bellies. Skeletal muscle degeneration progressed rapidly between 7 to 10 years of age, and reached a plateau after that. (author)

  1. Motor axon excitability during Wallerian degeneration

    DEFF Research Database (Denmark)

    Moldovan, Mihai; Alvarez, Susana; Krarup, Christian

    2008-01-01

    Axonal loss and degeneration are major factors in determining long-term outcome in patients with peripheral nerve disorders or injury. Following loss of axonal continuity, the isolated nerve stump distal to the lesion undergoes Wallerian degeneration in several phases. In the initial 'latent' phase...... at ankle distal to axotomy were monitored by 'threshold-tracking'. The plantar compound muscle action potentials (CMAPs) were recorded under anesthesia in three animal models: 8-week-old wild-type mice, 8-week-old slow Wallerian degeneration mutant mice and 3-year-old cats. We found that the progressive...... decrease in CMAP following crush injury was associated with slowing of conduction and marked abnormalities in excitability: increased peak threshold deviations during both depolarizing and hyperpolarizing threshold electrotonus, enhanced superexcitability during the recovery cycle and increased rheobase...

  2. Phase space methods for degenerate quantum gases

    CERN Document Server

    Dalton, Bryan J; Barnett, Stephen M

    2015-01-01

    Recent experimental progress has enabled cold atomic gases to be studied at nano-kelvin temperatures, creating new states of matter where quantum degeneracy occurs - Bose-Einstein condensates and degenerate Fermi gases. Such quantum states are of macroscopic dimensions. This book presents the phase space theory approach for treating the physics of degenerate quantum gases, an approach already widely used in quantum optics. However, degenerate quantum gases involve massive bosonic and fermionic atoms, not massless photons. The book begins with a review of Fock states for systems of identical atoms, where large numbers of atoms occupy the various single particle states or modes. First, separate modes are considered, and here the quantum density operator is represented by a phase space distribution function of phase space variables which replace mode annihilation, creation operators, the dynamical equation for the density operator determines a Fokker-Planck equation for the distribution function, and measurable...

  3. The chiral critical line of $N_{f}=2+1$ QCD at ero and non-zero baryon density

    CERN Document Server

    De Forcrand, Philippe; Forcrand, Philippe de; Philipsen, Owe

    2007-01-01

    We present numerical results for the location of the chiral critical line at finite temperature and zero and non-zero baryon density for QCD with N_f=2+1 flavours of staggered fermions on lattices with temporal extent N_t=4. For degenerate quark masses, we compare our results obtained with the exact RHMC algorithm with earlier, inexact R-algorithm results and find a reduction of 25% in the critical quark mass, for which the first order phase transition changes to a smooth crossover. Extending our analysis to non-degenerate quark masses, we map out the chiral critical line up to the neighbourhood of the physical point, which we confirm to be in the crossover region. Our data are consistent with a tricritical point at a strange quark mass of ~500 MeV. Finally, we investigate the shift of the critical line with finite baryon density, by simulating with an imaginary chemical potential for which there is no sign problem. We observe this shift to be very small or, conversely, the critical endpoint \\mu^c(m_{u,d},m_s...

  4. [New aspects in age related macular degeneration].

    Science.gov (United States)

    Turlea, C

    2012-01-01

    Being the leading cause of blindness in modern world Age Related Macular Degeneration has beneficiated in the last decade of important progress in diagnosis, classification and the discovery of diverse factors who contribute to the etiology of this disease. Treatments have arised who can postpone the irreversible evolution of the disease and thus preserve vision. Recent findings have identified predisposing genetic factors and also inflamatory and imunological parameters that can be modified trough a good and adequate prevention and therapy This articole reviews new aspects of patology of Age Related Macular Degeneration like the role of complement in maintaining inflamation and the role of oxidative stress on different structures of the retina.

  5. Late complications following cryotherapy of lattice degeneration.

    Science.gov (United States)

    Benson, W E; Morse, P H; Nantawan, P

    1977-10-01

    We observed 341 patients who had received cryotherapy for lattice degeneration in order to identify possible late complications. Sequelae such as retinal tears posterior to an operculum or flap tears within treated areas showed that treatment did not necessarily prevent subsequent vitreous traction. Moreover, the newly created flap tears may extend beyond the treated area and can cause retinal detachment. Even scleral buckling did not necesserily prevent further traction. Therefore, we concluded that when cryotherapy is used to treat lattice degeneration, an adequate margin of surrounding retina should be treated and the treatment should extend to the ora serrata.

  6. Genetics of lattice degeneration of the retina.

    Science.gov (United States)

    Murakami, F; Ohba, N

    1982-01-01

    First-degree relatives of proband patients with lattice degeneration of the retina revealed a significantly higher prevalence of the disease than the prevalence in the general population: the former had the disease about three times as frequently as the latter. The observed data were analyzed in terms of their accordance with recognized genetic models. The inheritance pattern did not fit well to a monogenic mode of inheritance, and it was hypothesized that a polygenic or multifactorial mode of inheritance is the most likely for lattice degeneration of the retina.

  7. CT of sarcomatous degeneration in neurofibromatosis

    International Nuclear Information System (INIS)

    Coleman, B.G.; Arger, P.H.; Dalinka, M.K.; Obringer, A.C.; Raney, B.R.; Meadows, A.T.

    1983-01-01

    Neurofibromatosis is a relatively common disorder that often involves many organ systems. One of the least understood aspects of this malady is a well documented potential for sarcomatous degeneration of neurofibromas. The inability to identify patients at risk and the lack of noninvasive screening methods for symptomatic patients often leads to late diagnosis. In six of seven subsequently proven neurofibrosarcomas, CT demonstrated low-density areas that histopathologically appeared to be due to necrosis, hemorrhage, and/or cystic degeneration. The density differences within these sarcomas were enhanced by the intravenous adminstration of iodinated contrast agents

  8. Gravitational black-holes-hedgehogs and two degenerate vacua of the Universe

    Science.gov (United States)

    Sidharth, B. G.; Das, C. R.; Laperashvili, L. V.; Nielsen, H. B.

    In the present paper, assuming the Multiple Point Principle (MPP) as a new law of Nature, we considered the existence of the two degenerate vacua of the Universe: the first Electroweak (EW) vacuum at v1 ≈ 246GeV — “true vacuum”, and the second Planck scale “false vacuum” at v2 ˜ 1018 GeV. In these vacua, we investigated different topological defects. The main aim of this paper is an investigation of the black-hole-hedgehogs configurations as defects of the false vacuum. In the framework of the f(R) gravity, described by the Gravi-Weak unification model, we considered a black-hole solution, which corresponds to a “hedgehog” — global monopole, that has been “swallowed” by the black-hole with mass core MBH ˜ 1018GeV and radius δ ˜ 10‑21GeV‑1. Considering the results of the hedgehog lattice theory in the framework of the SU(2) Yang-Mills gauge-invariant theory with hedgehogs in the Wilson loops, we have used the critical value of temperature for the hedgehogs confinement phase (Tc ˜ 1018GeV). This result gave us the possibility to conclude that the SM shows a new physics with contributions of the SU(2)-triplet Higgs bosons at the scale ˜10TeV. Theory predicts the stability of the EW-vacuum and the accuracy of the MPP.

  9. Análise e monitoramento de pontos críticos no abate de frangos utilizando indicadores microbiológicos Analysis and monitoring of critical points in the poultry slaughter using microbiological indicators

    Directory of Open Access Journals (Sweden)

    Augusto César Almeida Rodrigues

    2008-10-01

    Full Text Available A presença de microrganismos indicadores de contaminação na linha de abate de frangos foi determinada visando identificar os possíveis pontos de controle e oferecer uma opção para o monitoramento ou a verificação pelo sistema "Análise de Perigos e Pontos Críticos de Controle" (APPCC. A contaminação superficial das carcaças foi determinada pela enumeração de microrganismos aeróbios mesófilos, coliformes totais, coliformes termotolerantes e de Escherichia coli nas seguintes fases de abate: A - antes do primeiro chuveiro de higienização, B - após o primeiro chuveiro, C - após a evisceração manual, D - após o chuveiro de lavagem final e E - na saída do pré-resfriamento. Não houve diferença significativa (PHygiene indicator microorganisms in a poultry slaughter was evaluated during the processing in order to identify potential critical control points and allow options for monitoring or verification by Hazard Analysis Critical Control Point (HACCP system. Microbiological superficial contamination of chicken carcasses was establish by the enumeration of mesophilic aerobes, total coliforms, thermotolerant coliforms and Escherichia coli in the following steps of processing: A - before the first hygienic shower, B - after the first hygienic shower, C - after manual evisceration, D - after final washing shower, and E - after the chiller tank. The mean counts of mesophilic aerobes, total and thermotolerant coliforms was not significantly different (P<0.05 in the steps A, B, C and D. However, the mean values of these microorganisms in step E (after chilling was significantly lower when compared to the one obtained in the other steps. The mean counts of Escherichia coli were not significantly different, independently of the processing step analyzed. The chances of contamination were estimated by Odds Ration, and it was observed that chances were higher in the step A for mesophilic aerobes, and in the step C for coliforms

  10. Heterotic-type IIA duality and degenerations of K3 surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Braun, A.P. [Department of Mathematics, University of Oxford,Andrew Wiles Building, Woodstock Rd, Oxford OX2 6GG (United Kingdom); Watari, T. [Kavli Institute for the Physics and Mathematics of the Universe, University of Tokyo,Kashiwano-ha 5-1-5, 277-8583 (Japan)

    2016-08-04

    We study the duality between four-dimensional N=2 compactifications of heterotic and type IIA string theories. Via adiabatic fibration of the duality in six dimensions, type IIA string theory compactified on a K3-fibred Calabi-Yau threefold has a potential heterotic dual compactification. This adiabatic picture fails whenever the K3 fibre degenerates into multiple components over points in the base of the fibration. Guided by monodromy, we identify such degenerate K3 fibres as solitons generalizing the NS5-brane in heterotic string theory. The theory of degenerations of K3 surfaces can then be used to find which solitons can be present on the heterotic side. Similar to small instanton transitions, these solitons escort singular transitions between different Calabi-Yau threefolds. Starting from well-known examples of heterotic-type IIA duality, such transitions can take us to type IIA compactifications with unknown heterotic duals.

  11. Ex vivo quantitative multiparametric MRI mapping of human meniscus degeneration

    International Nuclear Information System (INIS)

    Nebelung, Sven; Kuhl, Christiane; Truhn, Daniel; Tingart, Markus; Jahr, Holger; Pufe, Thomas

    2016-01-01

    To evaluate the diagnostic performance of T1, T1ρ, T2, T2*, and UTE-T2* (ultrashort-echo time-enhanced T2*) mapping in the refined graduation of human meniscus degeneration with histology serving as standard-of-reference. This IRB-approved intra-individual comparative ex vivo study was performed on 24 lateral meniscus body samples obtained from 24 patients undergoing total knee replacement. Samples were assessed on a 3.0-T MRI scanner using inversion-recovery (T1), spin-lock multi-gradient-echo (T1ρ), multi-spin-echo (T2) and multi-gradient-echo (T2* and UTE-T2*) sequences to determine relaxation times of quantitative MRI (qMRI) parameters. Relaxation times were calculated on the respective maps, averaged to the entire meniscus and to its zones. Histologically, samples were analyzed on a four-point score according to Williams (0-III). QMRI results and Williams (sub)scores were correlated using Spearman's ρ, while Williams grade-dependent differences were assessed using Kruskal-Wallis and Dunn's tests. Sensitivities and specificities in the detection of intact (Williams grade [WG]-0) and severely degenerate meniscus (WG-II-III) were calculated. Except for T2*, significant increases in qMRI parameters with increasing Williams grades were observed. T1, T1ρ, T2, and UTE-T2* exhibited high sensitivity and variable specificity rates. Significant marked-to-strong correlations were observed for these parameters with each other, with histological WGs and the subscores tissue integrity and cellularity. QMRI mapping holds promise in the objective evaluation of human meniscus. Although sufficient discriminatory power of T1, T1ρ, T2, and UTE-T2* was only demonstrated for the histological extremes, these data may aid in the future MRI-based parameterization and quantification of human meniscus degeneration. (orig.)

  12. Ex vivo quantitative multiparametric MRI mapping of human meniscus degeneration.

    Science.gov (United States)

    Nebelung, Sven; Tingart, Markus; Pufe, Thomas; Kuhl, Christiane; Jahr, Holger; Truhn, Daniel

    2016-12-01

    To evaluate the diagnostic performance of T1, T1ρ, T2, T2*, and UTE-T2* (ultrashort-echo time-enhanced T2*) mapping in the refined graduation of human meniscus degeneration with histology serving as standard-of-reference. This IRB-approved intra-individual comparative ex vivo study was performed on 24 lateral meniscus body samples obtained from 24 patients undergoing total knee replacement. Samples were assessed on a 3.0-T MRI scanner using inversion-recovery (T1), spin-lock multi-gradient-echo (T1ρ), multi-spin-echo (T2) and multi-gradient-echo (T2* and UTE-T2*) sequences to determine relaxation times of quantitative MRI (qMRI) parameters. Relaxation times were calculated on the respective maps, averaged to the entire meniscus and to its zones. Histologically, samples were analyzed on a four-point score according to Williams (0-III). QMRI results and Williams (sub)scores were correlated using Spearman's ρ, while Williams grade-dependent differences were assessed using Kruskal-Wallis and Dunn's tests. Sensitivities and specificities in the detection of intact (Williams grade [WG]-0) and severely degenerate meniscus (WG-II-III) were calculated. Except for T2*, significant increases in qMRI parameters with increasing Williams grades were observed. T1, T1ρ, T2, and UTE-T2* exhibited high sensitivity and variable specificity rates. Significant marked-to-strong correlations were observed for these parameters with each other, with histological WGs and the subscores tissue integrity and cellularity. QMRI mapping holds promise in the objective evaluation of human meniscus. Although sufficient discriminatory power of T1, T1ρ, T2, and UTE-T2* was only demonstrated for the histological extremes, these data may aid in the future MRI-based parameterization and quantification of human meniscus degeneration.

  13. Ex vivo quantitative multiparametric MRI mapping of human meniscus degeneration

    Energy Technology Data Exchange (ETDEWEB)

    Nebelung, Sven; Kuhl, Christiane; Truhn, Daniel [Aachen University Hospital, Department of Diagnostic and Interventional Radiology, Aachen (Germany); Tingart, Markus; Jahr, Holger [Aachen University Hospital, Department of Orthopaedics, Aachen (Germany); Pufe, Thomas [RWTH Aachen University, Institute of Anatomy and Cell Biology, Aachen (Germany)

    2016-12-15

    To evaluate the diagnostic performance of T1, T1ρ, T2, T2*, and UTE-T2* (ultrashort-echo time-enhanced T2*) mapping in the refined graduation of human meniscus degeneration with histology serving as standard-of-reference. This IRB-approved intra-individual comparative ex vivo study was performed on 24 lateral meniscus body samples obtained from 24 patients undergoing total knee replacement. Samples were assessed on a 3.0-T MRI scanner using inversion-recovery (T1), spin-lock multi-gradient-echo (T1ρ), multi-spin-echo (T2) and multi-gradient-echo (T2* and UTE-T2*) sequences to determine relaxation times of quantitative MRI (qMRI) parameters. Relaxation times were calculated on the respective maps, averaged to the entire meniscus and to its zones. Histologically, samples were analyzed on a four-point score according to Williams (0-III). QMRI results and Williams (sub)scores were correlated using Spearman's ρ, while Williams grade-dependent differences were assessed using Kruskal-Wallis and Dunn's tests. Sensitivities and specificities in the detection of intact (Williams grade [WG]-0) and severely degenerate meniscus (WG-II-III) were calculated. Except for T2*, significant increases in qMRI parameters with increasing Williams grades were observed. T1, T1ρ, T2, and UTE-T2* exhibited high sensitivity and variable specificity rates. Significant marked-to-strong correlations were observed for these parameters with each other, with histological WGs and the subscores tissue integrity and cellularity. QMRI mapping holds promise in the objective evaluation of human meniscus. Although sufficient discriminatory power of T1, T1ρ, T2, and UTE-T2* was only demonstrated for the histological extremes, these data may aid in the future MRI-based parameterization and quantification of human meniscus degeneration. (orig.)

  14. Principal component analysis for fermionic critical points

    Science.gov (United States)

    Costa, Natanael C.; Hu, Wenjian; Bai, Z. J.; Scalettar, Richard T.; Singh, Rajiv R. P.

    2017-11-01

    We use determinant quantum Monte Carlo (DQMC), in combination with the principal component analysis (PCA) approach to unsupervised learning, to extract information about phase transitions in several of the most fundamental Hamiltonians describing strongly correlated materials. We first explore the zero-temperature antiferromagnet to singlet transition in the periodic Anderson model, the Mott insulating transition in the Hubbard model on a honeycomb lattice, and the magnetic transition in the 1/6-filled Lieb lattice. We then discuss the prospects for learning finite temperature superconducting transitions in the attractive Hubbard model, for which there is no sign problem. Finally, we investigate finite temperature charge density wave (CDW) transitions in the Holstein model, where the electrons are coupled to phonon degrees of freedom, and carry out a finite size scaling analysis to determine Tc. We examine the different behaviors associated with Hubbard-Stratonovich auxiliary field configurations on both the entire space-time lattice and on a single imaginary time slice, or other quantities, such as equal-time Green's and pair-pair correlation functions.

  15. QCD critical point: The race is on

    Indian Academy of Sciences (India)

    2015-05-06

    May 6, 2015 ... it is natural to extend the same approach to finite-temperature and finite-density QCD. Indeed, its application to .... Until that is achieved, one can only make qualitative comparisons. The hints of a ... method have been rather encouraging, as one has been able to study systematically. (i) the finite volume ...

  16. Percolation systems away from the critical point

    Indian Academy of Sciences (India)

    Pramana – Journal of Physics. Current Issue : Vol. 90, Issue 3 · Current Issue Volume 90 | Issue 3. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Search · Editorial Board · Information for Authors · Subscription ...

  17. Percolation systems away from the critical point

    Indian Academy of Sciences (India)

    a trap with trapping time bigger than t, and gets stuck there. Eventually, it will exit from this trap, only to get stuck in other traps, some with even larger trapping times. Thus, if we examine all particles at some large time t, typically they would be stuck in, or just emerging from a trap with trapping time of ordert. For B = Bc, the ...

  18. Prevention of criticality accidents

    International Nuclear Information System (INIS)

    Canavese, S.I.

    1982-01-01

    These notes used in the postgraduate course on Radiological Protection and Nuclear Safety discuss macro-and microscopic nuclear constants for fissile materials systems. Critical systems: their definition; criteria to analyze the critical state; determination of the critical size; analysis of practical problems about prevention of criticality. Safety of isolated units and of sets of units. Application of standards. Conception of facilities from the criticality control view point. (author) [es

  19. Tipping Point

    Medline Plus

    Full Text Available ... en español Blog About OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by ... danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe ...

  20. Nonthermal leptogenesis with almost degenerate superheavy neutrinos

    NARCIS (Netherlands)

    Allahverdi, Rouzbeh; Mazumdar, Anupam

    We present a model with minimal assumptions for nonthermal leptogenesis with almost degenerate superheavy right-handed neutrinos in a supersymmetric setup. In this scenario the gauge singlet inflaton is directly coupled to the right-handed (s)neutrinos with a mass heavier than the inflaton mass.

  1. Degenerate parabolic stochastic partial differential equations

    Czech Academy of Sciences Publication Activity Database

    Hofmanová, Martina

    2013-01-01

    Roč. 123, č. 12 (2013), s. 4294-4336 ISSN 0304-4149 R&D Projects: GA ČR GAP201/10/0752 Institutional support: RVO:67985556 Keywords : kinetic solutions * degenerate stochastic parabolic equations Subject RIV: BA - General Mathematics Impact factor: 1.046, year: 2013 http://library.utia.cas.cz/separaty/2013/SI/hofmanova-0397241.pdf

  2. MR findings of degenerating parenchymal neurocysticercosis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yul; Chung, Eun A; Yang, Ik; Park, Hae Jung; Chung, Soo Young [Hallym Univ. Kangnam Sungshim Hospital, Seoul (Korea, Republic of)

    1996-06-01

    To evaluate MR imaging findings of degenerating parenchymal neurocysticercosis and to determine the characteristics which distinguish it from other brain diseases. MR imagings of 19 patients (56 lesions) of degenerating parenchymal neurocysticercosis were retrospectively evaluated, focusing on the size and location of lesions signal intensity patterns of cyst fluid and wall, the extent of the surrounding edema and features of contrast enhancement. Degenerating parenchymal neurocysticercosis was located in gray or subcortical while matter in 89.3% of 56 lesions (50/56) ; most of these (98.2%) were smaller than 2 cm in diameter. Cyst fluid signal was hyperintense relative to CSF on T1 and proton density weighted images (92.9%). A hypointense signal rim of the cyst wall was noted in the lesions on proton density (92.9%) and T2 weighted (98.2%) images, Surrounding edema was mostly mild. Peripheral rim enhancement was noted in all lesions, and this was frequently irregular and lobulated (67.9%) with a focal defect in the enhancing rim(41.1%). Findings which could be helpful in distinguishing degenerating parencymal neurocysticercosis from other brain diseases are as follows : small, superficial lesions ; hyperintense signal of the cyst fluid on T1 and proton density weighted images ; hypointense signal of the cyst wall on proton density and T2 weighted images ; relatively mild extent of surrounding edema, and peripheral rim enhancement which is frequently irregular and lobulated with a focal defect in the enhancing rim.

  3. Geometry of non-degenerate Susskind fermions

    International Nuclear Information System (INIS)

    Mitra, P.

    1983-01-01

    The Dirac-Kaehler equation on the lattice is known to describe the degenerate ''flavours'' appering in Susskind's approach to lattice fermions. We study the modification that has to be made in this equation in order to lift the degeneracy and give the flavours arbitrary different masses. (orig.)

  4. MR findings of degenerating parenchymal neurocysticercosis

    International Nuclear Information System (INIS)

    Lee, Yul; Chung, Eun A; Yang, Ik; Park, Hae Jung; Chung, Soo Young

    1996-01-01

    To evaluate MR imaging findings of degenerating parenchymal neurocysticercosis and to determine the characteristics which distinguish it from other brain diseases. MR imagings of 19 patients (56 lesions) of degenerating parenchymal neurocysticercosis were retrospectively evaluated, focusing on the size and location of lesions signal intensity patterns of cyst fluid and wall, the extent of the surrounding edema and features of contrast enhancement. Degenerating parenchymal neurocysticercosis was located in gray or subcortical while matter in 89.3% of 56 lesions (50/56) ; most of these (98.2%) were smaller than 2 cm in diameter. Cyst fluid signal was hyperintense relative to CSF on T1 and proton density weighted images (92.9%). A hypointense signal rim of the cyst wall was noted in the lesions on proton density (92.9%) and T2 weighted (98.2%) images, Surrounding edema was mostly mild. Peripheral rim enhancement was noted in all lesions, and this was frequently irregular and lobulated (67.9%) with a focal defect in the enhancing rim(41.1%). Findings which could be helpful in distinguishing degenerating parencymal neurocysticercosis from other brain diseases are as follows : small, superficial lesions ; hyperintense signal of the cyst fluid on T1 and proton density weighted images ; hypointense signal of the cyst wall on proton density and T2 weighted images ; relatively mild extent of surrounding edema, and peripheral rim enhancement which is frequently irregular and lobulated with a focal defect in the enhancing rim

  5. Effect of amine uptake inhibitors on the uptake of 14C-bretylium in intact and degenerating sympathetic nerves of the rat

    International Nuclear Information System (INIS)

    Almgren, O.

    1981-01-01

    The effect of different amine uptake inhibitors on the accumulation of 14 C-bretylium in sympathetically denervated or decentralized salivary glands were studied in vivo in rats 11-14 hours after the surgical intervention. The time period chosen is known to be critical for the delaying effect of bretylium on the degeneration transmitter release in sympathetically innervated organs. Cocaine, desmethylimipramine (DMI), protriptyline or reserpine all depressed the uptake of 14 C-bretylium in both denervated and decentralized salivary glands, cocaine being the most efficient one. DMI and protriptyline, but not cocaine inhibit the degeneration delaying effect of bretylium, while all three agents inhibit amine uptake at level of the nerve cell membrane. Apparently, bretylium reaches the critical sites of its degeneration delaying action by the axonal amine pump but only a small fraction of the drug entering the degenerating adrenergic nerve terminal is needed at the critical sites to interact with the degeneration processes. The difference between the tricyclic antidepressants on one hand and cocaine on the other with respect to the effect on the degeneration delaying action of bretylium, must depend on some action different from the axonal membrane uptake inhibition. Reserpine which is known not to interfere with the delaying effect of bretylium on the denervation degeneration did reduce the uptake of 14 C-bretylium. This fact seems to indicate that the site of action of bretylium is located outside the adrenergic nerve granules. (author)

  6. Association between intervertebral disc degeneration and the Oswestry Disability Index.

    Science.gov (United States)

    Middendorp, Marcus; Vogl, Thomas J; Kollias, Konstantinos; Kafchitsas, Konstantinos; Khan, M Fawad; Maataoui, Adel

    2017-01-01

    Low back pain and lumbar intervertebral disc degeneration (IDD) are common findings. Valid data on correlation between clinical pain scores and grades of IDD are not available. To investigate the correlation of intervertebral disc degeneration (IDD) at lumbar levels L4/5 and L5/S1 and the Oswestry Disability Index (ODI). The lumbar discs L4/5 and L5/S1 of 591 patients were evaluated according to the 5-point (Grade I to Grade V) grading system as published by Pfirrmann et al. Functional status was assessed using the Oswestry Disability Index. Spearman's coefficient of rank correlation was used for statistical analysis (p disability (ODI score between 21 and 40%). There was a weak, but statistically significant positive correlation between IDD and ODI for both evaluated lumbar levels. Increased lumbar IDD in MRI goes along with an increased ODI. Thus, MRI is a strong indicator of a patient's clinical appearance. However, low back pain cannot be explained by imaging alone. Clinical correlation is imperative for an adequate diagnostic advance in patients with low back pain.

  7. MR imaging of central nervous system white matter tract degeneration (Wallerian degeneration)

    International Nuclear Information System (INIS)

    Kuhn, M.J.; Johnson, K.A.; Davis, K.R.

    1987-01-01

    Wallerian degeneration is readily demonstrated by MR imaging. Twenty-one patients with MR signal abnormalities in various central nervous system (CNS) white matter tracts were evaluated with regard to (1) nature of signal abnormality, (2) MR anatomy of the involved tract, and (3) primary pathology (e.g., infarct, tumor, hemorrhage). Most examples of wallerian degeneration result in a thin, continuous band of long T1, long T2 signal abnormality conforming to the known anatomic pathway of a CNS axonal tract. Old, large cortical infarcts have the greatest propensity to show subsequent white-matter tract degeneration. Corticospinal tract degeneration is the type most readily visualized, often seen extending completely from the cerebral cortex through the medulla

  8. Ethanol Exposure Causes Muscle Degeneration in Zebrafish

    Directory of Open Access Journals (Sweden)

    Elizabeth C. Coffey

    2018-03-01

    Full Text Available Alcoholic myopathies are characterized by neuromusculoskeletal symptoms such as compromised movement and weakness. Although these symptoms have been attributed to neurological damage, EtOH may also target skeletal muscle. EtOH exposure during zebrafish primary muscle development or adulthood results in smaller muscle fibers. However, the effects of EtOH exposure on skeletal muscle during the growth period that follows primary muscle development are not well understood. We determined the effects of EtOH exposure on muscle during this phase of development. Strikingly, muscle fibers at this stage are acutely sensitive to EtOH treatment: EtOH induces muscle degeneration. The severity of EtOH-induced muscle damage varies but muscle becomes more refractory to EtOH as muscle develops. NF-kB induction in muscle indicates that EtOH triggers a pro-inflammatory response. EtOH-induced muscle damage is p53-independent. Uptake of Evans blue dye shows that EtOH treatment causes sarcolemmal instability before muscle fiber detachment. Dystrophin-null sapje mutant zebrafish also exhibit sarcolemmal instability. We tested whether Trichostatin A (TSA, which reduces muscle degeneration in sapje mutants, would affect EtOH-treated zebrafish. We found that TSA and EtOH are a lethal combination. EtOH does, however, exacerbate muscle degeneration in sapje mutants. EtOH also disrupts adhesion of muscle fibers to their extracellular matrix at the myotendinous junction: some detached muscle fibers retain beta-Dystroglycan indicating failure of muscle end attachments. Overexpression of Paxillin, which reduces muscle degeneration in zebrafish deficient for beta-Dystroglycan, is not sufficient to rescue degeneration. Taken together, our results suggest that EtOH exposure has pleiotropic deleterious effects on skeletal muscle.

  9. MACULAR DEGENERATION AND ASPIRIN USE.

    Science.gov (United States)

    Small, Kent W; Garabetian, Christine A; Shaya, Fadi S

    2017-09-01

    To review current literature of the benefits that aspirin provides for patients' cardiovascular health compared with the risk of AMD worsening. We performed a review and critically analyzed six cardiovascular and four ophthalmological trials regarding risks and benefits of aspirin use. The prospective randomized cardiovascular trials had a cumulative 167,580 while the 3 smaller ophthalmological data sets had a cumulative 12,015 subjects. The reviewed meta-analysis literature demonstrated a statistically significant 32% reduction in the risk of nonfatal stroke with regular aspirin users. The study also documented that aspirin users decreased the risk of fatal vascular deaths by 15%. Of the three ophthalmological studies highlighting the adverse affects of aspirin association with AMD, all suggested an exacerbation of AMD without statistical significance and broad confidence bands. Overall, the number, size, and quality of the cardiovascular studies recommending aspirin use are far superior to the fewer, smaller and conflicting studies suggesting a possible adverse effect of aspirin use in relation to AMD. The benefits of aspirin usage include preserving the duration and quality of life by decreasing stroke and heart attack risk. These benefits seem to far outweigh the theoretical risks of possibly exacerbating wet AMD, which can be reasonably controlled with anti-VEGF therapy.

  10. Calcium channel blockers inhibit retinal degeneration in the retinal-degeneration-B mutant of Drosophila.

    Science.gov (United States)

    Sahly, I; Bar Nachum, S; Suss-Toby, E; Rom, A; Peretz, A; Kleiman, J; Byk, T; Selinger, Z; Minke, B

    1992-01-01

    Light accelerates degeneration of photoreceptor cells of the retinal degeneration B (rdgB) mutant of Drosophila. During early stages of degeneration, light stimuli evoke spikes from photoreceptors of the mutant fly; no spikes can be recorded from photoreceptors of the wild-type fly. Production of spike potentials from mutant photoreceptors was blocked by diltiazem, verapamil hydrochloride, and cadmium. Little, if any, effect of the (-)-cis isomer or (+)-cis isomer of diltiazem on the light response was seen. Further, the (+)-cis isomer was approximately 50 times more effective than the (-)-cis isomer in blocking the Ca2+ spikes, indicating that diltiazem action on the rdgB eye is mediated by means of blocking voltage-sensitive Ca2+ channels, rather than by blocking the light-sensitive channels. Application of the Ca(2+)-channel blockers (+)-cis-diltiazem and verapamil hydrochloride to the eyes of rdgB flies over a 7-day period largely inhibited light-dependent degeneration of the photoreceptor cells. Pulse labeling with [32P]phosphate showed much greater incorporation into eye proteins of [32P]phosphate in rdgB flies than in wild-type flies. Retarding the light-induced photoreceptor degeneration in the mutant by Ca(2+)-channel blockers, thus, suggests that toxic increase in intracellular Ca2+ by means of voltage-gated Ca2+ channels, possibly secondary to excessive phosphorylation, leads to photoreceptor degeneration in the rdgB mutant. Images PMID:1309615

  11. Mucoid degeneration of the anterior cruciate Ligament: a case report ...

    African Journals Online (AJOL)

    We report a case of mucoid degeneration of the anterior cruciate ligament (ACL). Mucoid degeneration of the ACL is a very rare cause of knee pain. There have been only some reported cases of mucoid degeneration of the ACL in the English literature. We reviewed previous reports and summarized clinical features and ...

  12. Degenerate r-Stirling Numbers and r-Bell Polynomials

    Science.gov (United States)

    Kim, T.; Yao, Y.; Kim, D. S.; Jang, G.-W.

    2018-01-01

    The purpose of this paper is to exploit umbral calculus in order to derive some properties, recurrence relations, and identities related to the degenerate r-Stirling numbers of the second kind and the degenerate r-Bell polynomials. Especially, we will express the degenerate r-Bell polynomials as linear combinations of many well-known families of special polynomials.

  13. Theatre and social criticism in African literature: socio-cultural ...

    African Journals Online (AJOL)

    Theatre and social criticism in African literature: socio-cultural consciousness in Alachi's “Dilemma of Oko” ... criticism with the tragedy of an individual victimized by society. Keywords: Social Criticism, Moral degeneration, Convergence of cultures, foreign phenomena, societal norms, Traditional ethics, Traditional institutions ...

  14. Tipping Point

    Medline Plus

    Full Text Available ... OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point ... 24 hours a day. For young children whose home is a playground, it’s the best way to ...

  15. Fixed Points

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 5. Fixed Points - From Russia with Love - A Primer of Fixed Point Theory. A K Vijaykumar. Book Review Volume 5 Issue 5 May 2000 pp 101-102. Fulltext. Click here to view fulltext PDF. Permanent link:

  16. Adjacent Segment Degeneration Following Anterior Cervical Discectomy and Fusion Versus the Bryan Cervical Disc Arthroplasty.

    Science.gov (United States)

    Yan, Suo-Zhou; Di, Jun; Shen, Yong

    2017-06-02

    BACKGROUND Anterior cervical discectomy and fusion (ACDF) is an established treatment for degenerative disease of the cervical disc, but adjacent segment degeneration or instability may develop long term. The aim of this study was to investigate the risk factors for adjacent segment degeneration following ACDF compared with the use of the Bryan artificial disc for cervical disc arthroplasty (CDA). MATERIAL AND METHODS A prospective comparative study included 93 patients who underwent ACDF or CDA with the Bryan artificial cervical disc between 2002 and 2004, and who had more than eight years of follow-up. There were 29 cases in the CDA group and 39 cases in ACDF group, with a follow-up rate of 73.12%. Clinical results and imaging data were assessed before and after surgery. RESULTS There was no significant difference between the two groups in radiographic parameters at each follow-up time point. There were 19 cases of adjacent segment degeneration (48.72%) in the ACDF group, and 13 cases of adjacent segment degeneration (44.83%) in the CDA group, with no statistically significant difference (P>0.05). Univariate analysis showed that advanced age (OR 1.271, 95% CI 1.005-1.607), low preoperative overall lordosis (OR 0.858, 95% CI 0.786-0.936) and low preoperative segmental lordosis (OR 1.185, 95% CI 1.086-1.193) were significantly correlated with adjacent segment degeneration. CONCLUSIONS Equally good clinical outcomes were achieved with both the ACDF and the Bryan CDA. Increasing patient age was associated with adjacent segment degeneration in both patient groups.

  17. Adjacent Segment Degeneration Following Anterior Cervical Discectomy and Fusion Versus the Bryan Cervical Disc Arthroplasty

    Science.gov (United States)

    Yan, Suo-Zhou; Di, Jun; Shen, Yong

    2017-01-01

    Background Anterior cervical discectomy and fusion (ACDF) is an established treatment for degenerative disease of the cervical disc, but adjacent segment degeneration or instability may develop long term. The aim of this study was to investigate the risk factors for adjacent segment degeneration following ACDF compared with the use of the Bryan artificial disc for cervical disc arthroplasty (CDA). Material/Methods A prospective comparative study included 93 patients who underwent ACDF or CDA with the Bryan artificial cervical disc between 2002 and 2004, and who had more than eight years of follow-up. There were 29 cases in the CDA group and 39 cases in ACDF group, with a follow-up rate of 73.12%. Clinical results and imaging data were assessed before and after surgery. Results There was no significant difference between the two groups in radiographic parameters at each follow-up time point. There were 19 cases of adjacent segment degeneration (48.72%) in the ACDF group, and 13 cases of adjacent segment degeneration (44.83%) in the CDA group, with no statistically significant difference (P>0.05). Univariate analysis showed that advanced age (OR 1.271, 95% CI 1.005–1.607), low preoperative overall lordosis (OR 0.858, 95% CI 0.786–0.936) and low preoperative segmental lordosis (OR 1.185, 95% CI 1.086–1.193) were significantly correlated with adjacent segment degeneration. Conclusions Equally good clinical outcomes were achieved with both the ACDF and the Bryan CDA. Increasing patient age was associated with adjacent segment degeneration in both patient groups. PMID:28574978

  18. Intravitreal NGF administration counteracts retina degeneration after permanent carotid artery occlusion in rat

    Directory of Open Access Journals (Sweden)

    De Sordi Nadia

    2009-05-01

    Full Text Available Abstract Background The neurotrophin nerve growth factor (NGF is produced by different cell types in the anterior and posterior eye, exerting a neuroprotective role in the adult life. The visual system is highly sensitive to NGF and the retina and optic nerve provides suitable subjects for the study of central nervous system degeneration. The model of bilateral carotid occlusion (two-vessel occlusion, 2VO is a well-established model for chronic brain hypoperfusion leading to brain capillary pathology, to retina and optic nerve degeneration. In order to study if a single intravitreal injection of NGF protects the retina and the optic nerve from degeneration during systemic circulatory diseases, we investigated morphological and molecular changes occurring in the retina and optic nerve of adult rats at different time-points (8, 30 and 75 days after bilateral carotid occlusion. Results We demonstrated that a single intravitreal injection of NGF (5 μg/3 μl performed 24 hours after 2VO ligation has a long-lasting protective effect on retina and optic nerve degeneration. NGF counteracts retinal ganglion cells degeneration by early affecting Bax/Bcl-2 balance- and c-jun- expression (at 8 days after 2VO. A single intravitreal NGF injection regulates the demyelination/remyelination balance after ischemic injury in the optic nerve toward remyelination (at 75 days after 2VO, as indicated by the MBP expression regulation, thus preventing optic nerve atrophy and ganglion cells degeneration. At 8 days, NGF does not modify 2VO-induced alteration in VEFG and related receptors mRNA expression. Conclusion The protective effect of exogenous NGF during this systemic circulatory disease seems to occur also by strengthening the effect of endogenous NGF, the synthesis of which is increased by vascular defect and also by the mechanical lesion associated with NGF or even vehicle intraocular delivery.

  19. Apathy in corticobasal degeneration: possible parietal involvement.

    Science.gov (United States)

    Moretti, Rita; Caberlotto, R; Signori, R

    Corticobasal degeneration is a rare disorder, which usually consists of a combination of complex movement disorders, apraxia and cortical changes. Its definition is still evolving and in 2013 an international consortium tried to develop new criteria, based on a systematic literature review. Over a long period of time, we carefully selected 23 patients who fulfilled the criteria for a diagnosis of corticobasal degeneration; all had the so-called corticobasal syndrome phenotype, in accordance with Armstrong et al. (2013). Through a dedicated study, we set out to study behavioral alterations, specifically apathy, and to compare the results obtained with those deriving from a well-defined Parkinson's disease population. On the basis of our limited but specific results, we argue for a possible role of the parietal neural networks as a determinant of apathy, and provide an overview of emerging data in the imaging and pathology literature.

  20. Patients' experiences of nursing actions during intravitreal treatment for wet age-related macular degeneration

    OpenAIRE

    Rönn Emsfors, Åsa; Elgán, Carina

    2015-01-01

    Purpose: The aim was to identify and describe nursing actions performed by nursing staff in which patients with wet age-related macular degeneration (AMD) experience good nursing care. Method: An explorative and descriptive qualitative design based on the Critical incident technique (CIT) was used. A strategic sample of 16 patients, aged 61-87 years (eleven women and five men) with wet AMD who received intravitreal treatment were interviewed. Results: Two main areas of good nursing care was i...

  1. Degenerate odd Poisson bracket on Grassmann variables

    International Nuclear Information System (INIS)

    Soroka, V.A.

    2000-01-01

    A linear degenerate odd Poisson bracket (antibracket) realized solely on Grassmann variables is proposed. It is revealed that this bracket has at once three Grassmann-odd nilpotent Δ-like differential operators of the first, second and third orders with respect to the Grassmann derivatives. It is shown that these Δ-like operators, together with the Grassmann-odd nilpotent Casimir function of this bracket, form a finite-dimensional Lie superalgebra

  2. Can Neutrinos be Degenerate in Mass?

    CERN Document Server

    Ellis, Jonathan Richard; Ellis, John; Lola, Smaragda

    1999-01-01

    We reconsider the possibility that the masses of the three light neutrinos of the Standard Model might be almost degenerate and close to the present upper limits from Tritium beta decay and cosmology. In such a scenario, the cancellations required by the latest upper limit on neutrinoless double-beta decay enforce near-maximal mixing that may be compatible only with the vacuum-oscillation scenario for solar neutrinos. We argue that the mixing angles yielded by degenerate neutrino mass-matrix textures are not in general stable under small perturbations. We evaluate within the MSSM the generation-dependent one-loop renormalization of neutrino mass-matrix textures that yielded degenerate masses and large mixing at the tree level. We find that m_{nu_e} > m_{nu_mu} > m_{nu_tau} after renormalization, excluding MSW effects on solar neutrinos. We verify that bimaximal mixing is not stable, and show that the renormalized masses and mixing angles are not compatible with all the experimental constraints, even for tanbe...

  3. Degenerate pressure driven modified nucleus-acoustic waves in degenerate plasmas

    Science.gov (United States)

    Mamun, A. A.

    2018-02-01

    The existence of degenerate pressure driven modified nucleus-acoustic (DPDMNA) waves propagating in a cold degenerate quantum plasma (DQP) system [containing cold inertialess degenerate electron species (DES), cold inertial non-degenerate light nucleus species (LNS), and stationary heavy nucleus species (HNS)] is predicted for the first time. The DPDMNA waves (in which the mass density of the cold LNS provides the inertia and the cold inertialess DES gives rise to the restoring force) are new since they completely disappear if the degenerate pressure of the cold DES is neglected. It is found that the phase speed (Vp) of the DPDMNA waves decreases with the rise of the charge number density of the stationary HNS for both non-relativistic and ultra-relativistic DES, and that the ultra-relativistic DES does not have any effect on Vp when β = 1, where β = Λc/Λe with Λ e = ne 0 - 1 / 3 being the average inter-electron distance in the DQP system and Λc being the constant (˜10-10 cm) for the DES. However, the ultra-relativistic DES does have quite a significant effect on Vp for β ≫ 1 and β ≪ 1, and the ultra-relativistic effect significantly enhances (reduces) Vp for β ≫ 1 (β ≪ 1). The DPDMNA waves and their dispersion properties are expected to be useful in understanding the basic features of the electrostatic perturbation mode in space and laboratory DQP systems.

  4. Tipping Point

    Medline Plus

    Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... see news reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The ...

  5. Nonlinear electromagnetic perturbations in a degenerate ultrarelativistic electron-positron plasma.

    Science.gov (United States)

    El-Taibany, W F; Mamun, A A

    2012-02-01

    Nonlinear propagation of fast and slow magnetosonic perturbation modes in an ultrarelativistic, ultracold, degenerate (extremely dense) electron positron (EP) plasma (containing ultrarelativistic, ultracold, degenerate electron and positron fluids) has been investigated by the reductive perturbation method. The Alfvén wave velocity is modified due to the presence of the enthalpy correction in the fluid equations of motion. The degenerate EP plasma system (under consideration) supports the Korteweg-de Vries (KdV) solitons, which are associated with either fast or slow magnetosonic perturbation modes. It is found that the ultrarelativistic model leads to compressive (rarefactive) electromagnetic solitons corresponding to the fast (slow) wave mode. There are certain critical angles, θ(c), at which no soliton solution is found corresponding to the fast wave mode. For the slow mode, the magnetic-field intensity affects both the soliton amplitude and width. It is also illustrated that the basic features of the electromagnetic solitary structures, which are found to exist in such a degenerate EP plasma, are significantly modified by the effects of enthalpy correction, electron and positron degeneracy, magnetic-field strength, and the relativistic effect. The applications of the results in a pair-plasma medium, which occurs in many astrophysical objects (e.g., pulsars, white dwarfs, and neutron stars) are briefly discussed.

  6. CriticalEd

    DEFF Research Database (Denmark)

    Kjellberg, Caspar Mølholt; Meredith, David

    2014-01-01

    such as Sibelius or Finale. It was hypothesized that it would be possible to develop a Sibelius plug-in, written in Manuscript 6, that would improve the critical editing work flow, but it was found that the capabilities of this scripting language were insufficient. Instead, a 3-part system was designed and built......, consisting of a Sibelius plug-in, a cross-platform application, called CriticalEd, and a REST-based solution, which handles data storage/retrieval. A prototype has been tested at the Danish Centre for Music Publication, and the results suggest that the system could greatly improve the efficiency......The best text method is commonly applied among music scholars engaged in producing critical editions. In this method, a comment list is compiled, consisting of variant readings and editorial emendations. This list is maintained by inserting the comments into a document as the changes are made...

  7. Apathy and impulsivity in frontotemporal lobar degeneration syndromes.

    Science.gov (United States)

    Lansdall, Claire J; Coyle-Gilchrist, Ian T S; Jones, P Simon; Vázquez Rodríguez, Patricia; Wilcox, Alicia; Wehmann, Eileen; Dick, Katrina M; Robbins, Trevor W; Rowe, James B

    2017-06-01

    Apathy and impulsivity are common and disabling consequences of frontotemporal lobar degeneration. They cause substantial carer distress, but their aetiology remains elusive. There are critical limitations to previous studies in this area including (i) the assessment of either apathy or impulsivity alone, despite their frequent co-existence; (ii) the assessment of behavioural changes within single diagnostic groups; and (iii) the use of limited sets of tasks or questions that relate to just one aspect of these multifactorial constructs. We proposed an alternative, dimensional approach that spans behavioural and language variants of frontotemporal dementia, progressive supranuclear palsy and corticobasal syndrome. This accommodates the commonalities of apathy and impulsivity across disorders and reveals their cognitive and anatomical bases. The ability to measure the components of apathy and impulsivity and their associated neural correlates across diagnostic groups would provide better novel targets for pharmacological manipulations, and facilitate new treatment strategies and strengthen translational models. We therefore sought to determine the neurocognitive components of apathy and impulsivity in frontotemporal lobar degeneration syndromes. The frequency and characteristics of apathy and impulsivity were determined by neuropsychological and behavioural assessments in 149 patients and 50 controls from the PIck's disease and Progressive supranuclear palsy Prevalence and INcidence study (PiPPIN). We derived dimensions of apathy and impulsivity using principal component analysis and employed these in volumetric analyses of grey and white matter in a subset of 70 patients (progressive supranuclear palsy, n = 22; corticobasal syndrome, n = 13; behavioural variant, n = 14; primary progressive aphasias, n = 21) and 27 control subjects. Apathy and impulsivity were present across diagnostic groups, despite being criteria for behavioural variant frontotemporal dementia

  8. Aneutronic Fusion in a Degenerate Plasma

    International Nuclear Information System (INIS)

    Son, S.; Fisch, N.J.

    2004-01-01

    In a Fermi-degenerate plasma, the electronic stopping of a slow ion is smaller than that given by the classical formula, because some transitions between the electron states are forbidden. The bremsstrahlung losses are then smaller, so that the nuclear burning of an aneutronic fuel is more efficient. Consequently, there occurs a parameter regime in which self-burning is possible. Practical obstacles in this regime that must be overcome before net energy can be realized include the compression of the fuel to an ultra dense state and the creation of a hot spot

  9. Malignant degeneration in neurofibromatosis: 3 case report

    International Nuclear Information System (INIS)

    Lee, Jong Moon; Kang, Eun Young; Lee, Nam Joon; Chung, Kyoo Byung; Suh, Won Hyuck

    1989-01-01

    Von Recklinghausen's nuerofilbromatosis is a kind of neurocutaneous syndrome characterized by skin, nervous system, neuromusculoskeletal manifestations. Most central and peripheral nervous neoplastic lesions in neurofibromatosis are benign but have a significant potential for malignant transformation such as neurofibrosarcoma, neurogenic sarcoma, malignant schwannoma. And it is relatively common disorder but malignant change with radiologic findings has been reported rarely in Korea. Recently we experienced three cases of malignant degeneration in neurofibromatosis and confirmed by pathology. So we report the cases with review including radiologic findings

  10. Aneutronic Fusion in a Degenerate Plasma

    Energy Technology Data Exchange (ETDEWEB)

    S. Son; N.J. Fisch

    2004-09-03

    In a Fermi-degenerate plasma, the electronic stopping of a slow ion is smaller than that given by the classical formula, because some transitions between the electron states are forbidden. The bremsstrahlung losses are then smaller, so that the nuclear burning of an aneutronic fuel is more efficient. Consequently, there occurs a parameter regime in which self-burning is possible. Practical obstacles in this regime that must be overcome before net energy can be realized include the compression of the fuel to an ultra dense state and the creation of a hot spot.

  11. MRI and MR tractography in bilateral hypertrophic olivary degeneration

    International Nuclear Information System (INIS)

    Sen, Debraj; Gulati, Yoginder S.; Malik, Virender; Mohimen, Aneesh; Sibi, Eranki; Reddy, Deepak Chandra

    2014-01-01

    Hypertrophic olivary degeneration is a trans-synaptic neuronal degeneration associated with hypertrophy of the inferior olivary nucleus due to a lesion in the triangle of Guillain-Mollaret. Familiarity with this entity on magnetic resonance imaging (MRI) is essential to avoid other erroneous ominous diagnoses. We present a case of bilateral hypertrophic olivary degeneration and discuss the etiopathogenesis and MRI findings in this entity. The contributory role of MR tractography in the diagnosis is also highlighted

  12. An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment

    OpenAIRE

    Mathew, David J.; Sarma, Saurabh Kumar; Basaiawmoit, Jennifer V.

    2016-01-01

    Lattice degeneration of the retina is not infrequently encountered on a dilated retinal examination and many of them do not need any intervention. We report a case of atypical lattice degeneration variant with peripheral retinal detachment. An asymptomatic 35-year-old lady with minimal refractive error was found to have extensive lattice degeneration, peripheral retinal detachment and fibrotic changes peripherally with elevation of retinal vessels on dilated retinal examination. There were al...

  13. Towards new treatment strategies for intervertebral disc degeneration : Pathophysiology, histological and biochemical changes in IVD degeneration

    NARCIS (Netherlands)

    Rutges, J.P.H.J.

    2014-01-01

    Approximately 70% to 80% of all people worldwide will experience low back at any moment in their life. Intervertebral disc degeneration is an important cause of chronic low back pain. In most cases chronic low back pain can be treated conservatively with physiotherapy and analgesia. However, in some

  14. Stability of equilibrium solutions of Hamiltonian systems with n-degrees of freedom and single resonance in the critical case

    Science.gov (United States)

    dos Santos, Fabio; Vidal, Claudio

    2018-04-01

    In this paper we give new results for the stability of one equilibrium solution of an autonomous analytic Hamiltonian system in a neighborhood of the equilibrium point with n-degrees of freedom. Our Main Theorem generalizes several results existing in the literature and mainly we give information in the critical cases (i.e., the condition of stability and instability is not fulfilled). In particular, our Main Theorem provides necessary and sufficient conditions for stability of the equilibrium solutions under the existence of a single resonance. Using analogous tools used in the Main Theorem for the critical case, we study the stability or instability of degenerate equilibrium points in Hamiltonian systems with one degree of freedom. We apply our results to the stability of Hamiltonians of the type of cosmological models as in planar as in the spatial case.

  15. The prognosis of retinal detachment due to lattice degeneration.

    Science.gov (United States)

    Benson, W E; Morse, P H

    1978-09-01

    In a series of 553 consecutive retinal detachments, 29% (120) were due to lattice degeneration. Forty-five percent of these were due to atrophic holes in the lattice degeneration and 55% were due to tears caused by traction posterior to or at the end of a patch of lattice. In phakic patients, retinal detachments due to atrophic holes were most common in young myopes. Detachments due to traction tears were seen in older, less myopic patients. The incidence of massive periretinal proliferation was less (5%) in detachments due to lattice degeneration than in detachments not due to lattice degeneration (6.5%).

  16. Many-Body Green Function of Degenerate Systems

    International Nuclear Information System (INIS)

    Brouder, Christian; Panati, Gianluca; Stoltz, Gabriel

    2009-01-01

    A rigorous nonperturbative adiabatic approximation of the evolution operator in the many-body physics of degenerate systems is derived. This approximation is used to solve the long-standing problem of the choice of the initial states of H 0 leading to eigenstates of H 0 +V for degenerate systems. These initial states are eigenstates of P 0 VP 0 , where P 0 is the projection onto a degenerate eigenspace of H 0 . This result is used to give the proper definition of the Green function, the statistical Green function and the nonequilibrium Green function of degenerate systems. The convergence of these Green functions is established.

  17. Nuclei in neutrino-degenerate dense matter, 1

    International Nuclear Information System (INIS)

    Ogasawara, Ryusuke; Sato, Katsuhiko

    1982-01-01

    The properties of nuclei in cold dense matter with strongly degenerate neutrinos are investigated with the aid of an extended Thomas-Fermi model of nuclei. The following results are obtained. 1) The proton number of nucleus increases with the increasing density of the matter and it becomes very huge compared with that of the cold catalyzed matter due to the decrease of the Coulomb energy caused by the effect of the lattice-Coulomb energy. 2) The matter densities at the neutron-drip points, where the chemical potentials of neutrons equal zero are obtained as a function of the number of leptons per nucleon Y sub(L), and it is found that nuclei coalesce before neutron drip when Y sub(L) is greater than about 0.4 for the case b.c.c. lattice. 3) Along the neutron-drip points, an infinite network of linked nuclei may be formed at the matter density rho sub(P) asymptotically equals 9 x 10 13 g cm - 3 , and the bubble-phase appears at the matter density rho sub(B) asymptotically equals 1.1 x 10 14 g cm - 3 . When the matter density becomes higher than rho sub(H) asymptotically equals 1.7 x 10 14 g cm - 3 , the bubbles melt into a homogeneous matter. (author)

  18. MR imaging findings of hypertrophic olivary degeneration

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Do Joong; Jeon, Pyung; Kim, Dong Ik [Yonsei Univ. College of Medicine, Seoul (Korea, Republic of)

    1997-06-01

    To describe the magnetic resonance (MR) imaging findings of hypertrophic olivary degeneration (HOD) MR images of seven patients with HOD were retrospectively reviewed. Two were women and five were men, and they were aged between 48 and 65 (mean 58) years. Imaging examinations were performed with a 1.5-T unit, and the findings were used to evaluate the size and signal intensity of olivary lesions. The time interval from hemorrhagic ictus to MR imaging was between two and 30 months. Follow-up examinations were performed in two patients. All four patients with hemorrhages involving the central tegmental tract in the pons or midbrain showed ipsilateral HOD. Among these four, bilateral HOD was seen in one patient with hemorrhage involving the bilateral central tegmental tract, and in another with tegmental hemorrhage extending to the ipsilateral superior cerebellar peduncle. One patient with cerebellar hemorrhage involving the dentate nucleus had contralateral HOD. Two patients with multiple hemorrhages involving both the pons and cerebellum showed bilateral HOD. Axial MR images showed mild enlargement of the involved olivary mucleus, with high signal intensity on both proton density and T2 weighted images. There was no apparent enhancement on postcontrast T1-weighted images. MR imaging can clearly distinguish secondary olivary degeneration from underlying pathology involving the central tegmental tract in the pons or midbrain and cerebellum. These olivary abnormalities should not, however, be mistaken for primary medullary lesions.

  19. Changes in ganglion cells during retinal degeneration.

    Science.gov (United States)

    Saha, Susmita; Greferath, Ursula; Vessey, Kirstan A; Grayden, David B; Burkitt, Anthony N; Fletcher, Erica L

    2016-08-04

    Inherited retinal degeneration such as retinitis pigmentosa (RP) is associated with photoreceptor loss and concomitant morphological and functional changes in the inner retina. It is not known whether these changes are associated with changes in the density and distribution of synaptic inputs to retinal ganglion cells (RGCs). We quantified changes in ganglion cell density in rd1 and age-matched C57BL/6J-(wildtype, WT) mice using the immunocytochemical marker, RBPMS. Our data revealed that following complete loss of photoreceptors, (∼3months of age), there was a reduction in ganglion cell density in the peripheral retina. We next examined changes in synaptic inputs to A type ganglion cells by performing double labeling experiments in mice with the ganglion cell reporter lines, rd1-Thy1 and age-matched wildtype-Thy1. Ribbon synapses were identified by co-labelling with CtBP2 (RIBEYE) and conventional synapses with the clustering molecule, gephyrin. ON RGCs showed a significant reduction in RIBEYE-immunoreactive synapse density while OFF RGCs showed a significant reduction in the gephyrin-immmunoreactive synapse density. Distribution patterns of both synaptic markers across the dendritic trees of RGCs were unchanged. The change in synaptic inputs to RGCs was associated with a reduction in the number of immunolabeled rod bipolar and ON cone bipolar cells. These results suggest that functional changes reported in ganglion cells during retinal degeneration could be attributed to loss of synaptic inputs. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

  20. MR imaging findings of hypertrophic olivary degeneration

    International Nuclear Information System (INIS)

    Kim, Do Joong; Jeon, Pyung; Kim, Dong Ik

    1997-01-01

    To describe the magnetic resonance (MR) imaging findings of hypertrophic olivary degeneration (HOD) MR images of seven patients with HOD were retrospectively reviewed. Two were women and five were men, and they were aged between 48 and 65 (mean 58) years. Imaging examinations were performed with a 1.5-T unit, and the findings were used to evaluate the size and signal intensity of olivary lesions. The time interval from hemorrhagic ictus to MR imaging was between two and 30 months. Follow-up examinations were performed in two patients. All four patients with hemorrhages involving the central tegmental tract in the pons or midbrain showed ipsilateral HOD. Among these four, bilateral HOD was seen in one patient with hemorrhage involving the bilateral central tegmental tract, and in another with tegmental hemorrhage extending to the ipsilateral superior cerebellar peduncle. One patient with cerebellar hemorrhage involving the dentate nucleus had contralateral HOD. Two patients with multiple hemorrhages involving both the pons and cerebellum showed bilateral HOD. Axial MR images showed mild enlargement of the involved olivary mucleus, with high signal intensity on both proton density and T2 weighted images. There was no apparent enhancement on postcontrast T1-weighted images. MR imaging can clearly distinguish secondary olivary degeneration from underlying pathology involving the central tegmental tract in the pons or midbrain and cerebellum. These olivary abnormalities should not, however, be mistaken for primary medullary lesions