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Sample records for deformation linear response

  1. Linear response of light deformed nuclei investigated by self-consistent quasiparticle random-phase-approximation

    CERN Document Server

    Losa, C; Dossing, T; Vigezzi, E; Broglia, R A

    2010-01-01

    We present a calculation of the properties of vibrational states in deformed, axially--symmetric even--even nuclei, within the framework of a fully self--consistent Quasparticle Random Phase Approximation (QRPA). The same Skyrme energy density and density-dependent pairing functionals are used to calculate the mean field and the residual interaction in the particle-hole and particle-particle channels. We have tested our software in the case of spherical nuclei against fully self consistent calculations published in the literature, finding excellent agreement. We investigate the consequences of neglecting the spin-orbit and Coulomb residual interactions in QRPA. Furthermore we discuss the improvement obtained in the QRPA result associated with the removal of spurious modes. Isoscalar and isovector responses in the deformed ${}^{24}{}^{-}{}^{26}$Mg, ${}^{34}$Mg isotopes are presented and compared to experimental findings.

  2. Non-linear elastic deformations

    CERN Document Server

    Ogden, R W

    1997-01-01

    Classic in the field covers application of theory of finite elasticity to solution of boundary-value problems, analysis of mechanical properties of solid materials capable of large elastic deformations. Problems. References.

  3. Deformation in locally convex topological linear spaces

    Institute of Scientific and Technical Information of China (English)

    DING; Yanheng

    2004-01-01

    We are concerned with a deformation theory in locally convex topological linear spaces. A special "nice" partition of unity is given. This enables us to construct certain vector fields which are locally Lipschitz continuous with respect to the locally convex topology. The existence, uniqueness and continuous dependence of flows associated to the vector fields are established. Deformations related to strongly indefinite functionals are then obtained. Finally, as applications, we prove some abstract critical point theorems.

  4. Unobservable Planar Bimodal Linear Systems: Miniversal Deformations, Controllability and Stabilization

    CERN Document Server

    Ferrer, Josep; Pacha, Juan R; Peña, Marta

    2012-01-01

    We consider the set of bimodal linear systems consisting of two linear dynamics acting on each side of a given hyperplane, assuming continuity along the separating hyperplane. Focusing on the unobservable planar ones, we obtain a simple explicit characterization of controllability. Moreover, we apply the canonical forms of these systems depending on two state variables to obtain explicitly miniversal deformations, to illustrate bifurcation diagrams and to prove that the unobservable controllable systems are stabilizable. Preprint of an article submitted for consideration in IJBC \\copyright 2011 copyright World Scientific Publishing Company http://www.worldscinet.com/ijbc/

  5. Hierarchical Non-linear Image Registration Integrating Deformable Segmentation

    Institute of Scientific and Technical Information of China (English)

    RAN Xin; QI Fei-hu

    2005-01-01

    A hierarchical non-linear method for image registration was presented, which integrates image segmentation and registration under a variational framework. An improved deformable model is used to simultaneously segment and register feature from multiple images. The objects in the image pair are segmented by evolving a single contour and meanwhile the parameters of affine registration transformation are found out. After that, a contour-constrained elastic registration is applied to register the images correctly. The experimental results indicate that the proposed approach is effective to segment and register medical images.

  6. Inter and intra-modal deformable registration: continuous deformations meet efficient optimal linear programming.

    Science.gov (United States)

    Glocker, Ben; Paragios, Nikos; Komodakis, Nikos; Tziritas, Georgios; Navab, Nassir

    2007-01-01

    In this paper we propose a novel non-rigid volume registration based on discrete labeling and linear programming. The proposed framework reformulates registration as a minimal path extraction in a weighted graph. The space of solutions is represented using a set of a labels which are assigned to predefined displacements. The graph topology corresponds to a superimposed regular grid onto the volume. Links between neighborhood control points introduce smoothness, while links between the graph nodes and the labels (end-nodes) measure the cost induced to the objective function through the selection of a particular deformation for a given control point once projected to the entire volume domain, Higher order polynomials are used to express the volume deformation from the ones of the control points. Efficient linear programming that can guarantee the optimal solution up to (a user-defined) bound is considered to recover the optimal registration parameters. Therefore, the method is gradient free, can encode various similarity metrics (simple changes on the graph construction), can guarantee a globally sub-optimal solution and is computational tractable. Experimental validation using simulated data with known deformation, as well as manually segmented data demonstrate the extreme potentials of our approach.

  7. Linear response of hot gluons

    Science.gov (United States)

    Carrington, M. E.; Hansson, T. H.; Yamagishi, H.; Zahed, I.

    1989-03-01

    We reexamine the various schemes for calculating the linear response (the retarded Green's function) of a hot gluon plasma. The problems related to gauge invariance are discussed in detail, and results in different gauges are compared. We also point out some issues related to the very definition of a thermal ensemble in the presence of unphysical degrees of freedom. By culculating the retarded Green's function directly in real time, we explicitly study the effects of unphysical degrees of freedom in different gauges. Although there appears to be no unique way to define the response function, we find that several schemes can be questioned on formal grounds and that use of the background-field gauge (BFG) is the most satisfactory in this respect. We discuss two proposals to fix the gauge parameter (α) dependence in the BFG response function, the Vilkovisky-DeWitt effective action corresponding to the choice α = 0 (background Landau gauge), and the "gauge-invariant propagator" of Cornwall et al. corresponding to α = 1 (background Feynman gauge).

  8. Continuum Mechanics Based Bi-linear Shear Deformable Shell Element Using Absolute Nodal Coordinate Formulation

    Science.gov (United States)

    2014-03-07

    the convergent solution in the case of the continuum mechanics based bi- linear shear deformable ANCF shell element. 5.3 Slit Annular Plate Subjected...UNCLASSIFIED: Distribution Statement A. Approved for public release. #24515 CONTINUUM MECHANICS BASED BI- LINEAR SHEAR DEFORMABLE SHELL ELEMENT...MAR 2014 2. REPORT TYPE Technical Report 3. DATES COVERED 07-01-2014 to 04-03-2014 4. TITLE AND SUBTITLE CONTINUUM MECHANICS BASED BI- LINEAR

  9. Non linear bend instability theory and finite amplitude evolution of bed deformations in meandering rivers

    Science.gov (United States)

    Bolla Pittaluga, M.; Nobile, G.; Seminara, G.

    2007-12-01

    We develop a three dimensional non linear asymptotic theory for flow and bed topography in meandering channels able to describe finite amplitude perturbations of bottom topography. The model extends a previous analysis on the equilibrium finite bed deformations, accounting here for arbitrary, yet slow, variations of channel curvature. This approach then allows us to formulate a non-linear bend instability theory, which predicts several characteristic features of the actual meandering process and extends results obtained by classical linear bend theories. In agreement with previous weakly non linear findings and consistently with field observations, the bend growth rate turns out to have a peak at some value of the meander wavenumber, typically larger than the resonant value of linear stability theory. Moreover, a feature typical of non linear waves arises: the selected wavenumber depends on the amplitude of the initial perturbation and, in particular, larger wavelengths are associated with larger amplitudes. The picture offered by results obtained through the present theory seems fully satisfactory and consistent with field observations as well as previous theoretical findings. Further substantiation of the model has been achieved by comparing predictions obtained for a test case (a reach of the Cecina river, Italy) with field observations. Finally the model is also extended to follow the evolution of bed deformations in time in order to investigate the morphological response of the river to a sequence of flood events characterized by a slow temporal variation of flow and sediment supply. Such an investigation would possibly provide a rational interpretation of the as yet loosely defined notion of formative discharge of an alluvial river.

  10. The Simulation and Correction to the Brain Deformation Based on the Linear Elastic Model in IGS

    Institute of Scientific and Technical Information of China (English)

    MUXiao-lan; SONGZhi-jian

    2004-01-01

    The brain deformation is a vital factor affecting the precision of the IGS and it becomes a hotspot to simulate and correct the brain deformation recently.The research organizations, which firstly resolved the brain deformation with the physical models, have the Image Processing and Analysis department of Yale University, Biomedical Modeling Lab of Vanderbilt University and so on. The former uses the linear elastic model; the latter uses the consolidation model.

  11. Shape-based image reconstruction using linearized deformations

    Science.gov (United States)

    Öktem, Ozan; Chen, Chong; Onur Domaniç, Nevzat; Ravikumar, Pradeep; Bajaj, Chandrajit

    2017-03-01

    We introduce a reconstruction framework that can account for shape related prior information in imaging-related inverse problems. It is a variational scheme that uses a shape functional, whose definition is based on deformable template machinery from computational anatomy. We prove existence and, as a proof of concept, we apply the proposed shape-based reconstruction to 2D tomography with very sparse and/or highly noisy measurements.

  12. The Simulation and Correction to the Brain Deformation Based on the Linear Elastic Model in IGS

    Institute of Scientific and Technical Information of China (English)

    MU Xiao-lan; SONG Zhi-jian

    2004-01-01

    @@ The brain deformation is a vital factor affecting the precision of the IGS and it becomes a hotspot to simulate and correct the brain deformation recently.The research organizations, which firstly resolved the brain deformation with the physical models, have the Image Processing and Analysis department of Yale University, Biomedical Modeling Lab of Vanderbilt University and so on. The former uses the linear elastic model; the latter uses the consolidation model.The linear elastic model only needs to drive the model using the surface displacement of exposed brain cortex,which is more convenient to be measured in the clinic.

  13. Mass-deformed $T_N$ as a linear quiver

    CERN Document Server

    Hayashi, Hirotaka; Yonekura, Kazuya

    2014-01-01

    The $T_N$ theory is a non-Lagrangian theory with SU(N) flavor symmetry. We argue that when mass terms are given so that two of SU(N)'s are both broken to SU(N-1) x U(1), it becomes $T_{N-1}$ theory coupled to an SU(N-1) vector multiplet together with N fundamentals. This implies that when two of SU(N)'s are both broken to U(1)$^{N-1}$, the theory becomes a linear quiver. We perform various checks of this statement, by using the 5d partition function, the structure of the coupling constants, the Higgs branch, and the Seiberg-Witten curve. We also study the case with more general punctures.

  14. Problem of probabilistic calculation of the design on linearly and non-linearly deformable basis with casual parameters

    Directory of Open Access Journals (Sweden)

    Mkrtychev Oleg Vartanovich

    Full Text Available In the article the problem of calculation of a construction basis system in case of earthquake is considered taking into account casual properties of basis soil in various points of the soil body. As a stochastic function in the calculation of linearly deformable basis, the deformation module, which accepts different values in the direction x, y, z, was chosen. In the calculation of the system on non-linearly deformable basis as incidentally distributed sizes the following parameters were accepted: deformation module, shear modulus, specific adhesion, angle of internal friction. The authors of the article offer to consider initial seismic influence in the form of casual stationary process. In order to solve such problems modern software systems are proposed that solve differential equations of motion via direct integration with explicit schemes. The calculation in this case will be held on the synthesized accelerograms. A short review of the task solution of the beam lying on elastic basis, which was received by D.N. Sobolev at casual distribution of pastel coefficient in the direction x, is provided in article. In order to define the objective, D.N. Sobolev gives expressions for a population mean and correlation function of stochastic function. As a result of the task solution population means and dispersions of function of movements and its derivatives were received. The problem formulation considered in the article is more complicated, but at the same time important from a practical standpoint.

  15. Linear response theory for quantum open systems

    OpenAIRE

    Wei, J. H.; Yan, YiJing

    2011-01-01

    Basing on the theory of Feynman's influence functional and its hierarchical equations of motion, we develop a linear response theory for quantum open systems. Our theory provides an effective way to calculate dynamical observables of a quantum open system at its steady-state, which can be applied to various fields of non-equilibrium condensed matter physics.

  16. Linear Response Laws and Causality in Electrodynamics

    Science.gov (United States)

    Yuffa, Alex J.; Scales, John A.

    2012-01-01

    Linear response laws and causality (the effect cannot precede the cause) are of fundamental importance in physics. In the context of classical electrodynamics, students often have a difficult time grasping these concepts because the physics is obscured by the intermingling of the time and frequency domains. In this paper, we analyse the linear…

  17. Fluctuations and Linear Response in Supercooled Liquids

    DEFF Research Database (Denmark)

    Nielsen, Johannes K.

    Fluctuation dissipation theorems are derived for thermodynamic properties like frequency dependent specific heat and compressibility. First the case where a systems dynamics are restricted by constant volume and energy is considered. The dynamic linear response to a heat pulse and a volume change...... at time zero is calculated, under assumption of energy conservation. Then the case of isothermal isobaric conditions are treated by a slight modification of ordinary linear response theory. In both cases the perturbation cannot be stated through the Hamiltonian, but has to be imposed by variation...... of the external thermodynamic system parameters. In thermodynamic response theory equivalence between ensembles is broken, but time correlation functions sampled in different ensembles are connected through the Maxwell relations of thermodynamics generalized to the frequency domain. Different applications...

  18. Plane linear waves in deformable electromagnetic materials with an extended description of the electromagnetism

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, T.; Strawinska, J. [Politechnika Poznanska, Poznan (Poland)

    1993-12-31

    The present considerations are devoted to the description of an electromagnetic field in deformable body within the framework of the conceptional extended electrodynamics. The formal tool used is the classical field theory based on methods of analytical mechanics. The deformation is described by applying the relativistic kinematics of a medium which makes it possible to obtain, as a particular case, three dimensional laws with simple physical interpretation. The dynamics of bodies interacting with an electromagnetic field has been expressed by Lagrange`s equation of motion with a view to obtaining linear field equations. In the domain of wave problems one-dimensional volume waves have been analysed. (author). 19 refs.

  19. Linear Response Calculations of Spin Fluctuations

    Science.gov (United States)

    Savrasov, S. Y.

    1998-09-01

    A variational formulation of the time-dependent linear response based on the Sternheimer method is developed in order to make practical ab initio calculations of dynamical spin susceptibilities of solids. Using gradient density functional and a muffin-tin-orbital representation, the efficiency of the approach is demonstrated by applications to selected magnetic and strongly paramagnetic metals. The results are found to be consistent with experiment and are compared with previous theoretical calculations.

  20. A non-linear elastic constitutive framework for replicating plastic deformation in solids.

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Scott Alan; Schunk, Peter Randall

    2014-02-01

    Ductile metals and other materials typically deform plastically under large applied loads; a behavior most often modeled using plastic deformation constitutive models. However, it is possible to capture some of the key behaviors of plastic deformation using only the framework for nonlinear elastic mechanics. In this paper, we develop a phenomenological, hysteretic, nonlinear elastic constitutive model that captures many of the features expected of a plastic deformation model. This model is based on calculating a secant modulus directly from a materials stress-strain curve. Scalar stress and strain values are obtained in three dimensions by using the von Mises invariants. Hysteresis is incorporated by tracking an additional history variable and assuming an elastic unloading response. This model is demonstrated in both single- and multi-element simulations under varying strain conditions.

  1. Nonlinearity and Strain-Rate Dependence in the Deformation Response of Polymer Matrix Composites Modeled

    Science.gov (United States)

    Goldberg, Robert K.

    2000-01-01

    There has been no accurate procedure for modeling the high-speed impact of composite materials, but such an analytical capability will be required in designing reliable lightweight engine-containment systems. The majority of the models in use assume a linear elastic material response that does not vary with strain rate. However, for containment systems, polymer matrix composites incorporating ductile polymers are likely to be used. For such a material, the deformation response is likely to be nonlinear and to vary with strain rate. An analytical model has been developed at the NASA Glenn Research Center at Lewis Field that incorporates both of these features. A set of constitutive equations that was originally developed to analyze the viscoplastic deformation of metals (Ramaswamy-Stouffer equations) was modified to simulate the nonlinear, rate-dependent deformation of polymers. Specifically, the effects of hydrostatic stresses on the inelastic response, which can be significant in polymers, were accounted for by a modification of the definition of the effective stress. The constitutive equations were then incorporated into a composite micromechanics model based on the mechanics of materials theory. This theory predicts the deformation response of a composite material from the properties and behavior of the individual constituents. In this manner, the nonlinear, rate-dependent deformation response of a polymer matrix composite can be predicted.

  2. Responsive gelation of hydrophobized linear polymer

    DEFF Research Database (Denmark)

    Madsen, Claus Greve; Toeth, Joachim; Jørgensen, Lene;

    In this study we present the rheological properties of a physically linked polymer network, composed of linear hydrophilic chains, modified with hydrophobic moieties in each end. Solutions of the polymer in ethanol-water mixtures showed Newtonian behaviour up to about 99 % ethanol, with the highest...... viscosity observed in a 1:1 mixture of ethanol and water. In pure ethanol, the polymer forms a thermo-responsive, non-Newtonian gel, which collapses upon addition of as little as 1 % water or heating to about 40 °C....

  3. Linear response approximation in effective field theory for the calculation of elastically mediated interactions in one dimension.

    Science.gov (United States)

    Koleski, Goce; Fournier, Jean-Baptiste

    2016-05-01

    The linear response approximation, used within effective field theory to calculate mediated interactions between inclusions, is studied for an exactly solvable one-dimensional model. We show that it works poorly in the case of inclusions imposing absolute deformations to the field, while it works well for massless theories in the case of inclusions imposing relative deformations to the field.

  4. Linear friction weld process monitoring of fixture cassette deformations using empirical mode decomposition

    Science.gov (United States)

    Bakker, O. J.; Gibson, C.; Wilson, P.; Lohse, N.; Popov, A. A.

    2015-10-01

    Due to its inherent advantages, linear friction welding is a solid-state joining process of increasing importance to the aerospace, automotive, medical and power generation equipment industries. Tangential oscillations and forge stroke during the burn-off phase of the joining process introduce essential dynamic forces, which can also be detrimental to the welding process. Since burn-off is a critical phase in the manufacturing stage, process monitoring is fundamental for quality and stability control purposes. This study aims to improve workholding stability through the analysis of fixture cassette deformations. Methods and procedures for process monitoring are developed and implemented in a fail-or-pass assessment system for fixture cassette deformations during the burn-off phase. Additionally, the de-noised signals are compared to results from previous production runs. The observed deformations as a consequence of the forces acting on the fixture cassette are measured directly during the welding process. Data on the linear friction-welding machine are acquired and de-noised using empirical mode decomposition, before the burn-off phase is extracted. This approach enables a direct, objective comparison of the signal features with trends from previous successful welds. The capacity of the whole process monitoring system is validated and demonstrated through the analysis of a large number of signals obtained from welding experiments.

  5. Study of non-linear deformation of vocal folds in simulations of human phonation

    Science.gov (United States)

    Saurabh, Shakti; Bodony, Daniel

    2014-11-01

    Direct numerical simulation is performed on a two-dimensional compressible, viscous fluid interacting with a non-linear, viscoelastic solid as a model for the generation of the human voice. The vocal fold (VF) tissues are modeled as multi-layered with varying stiffness in each layer and using a finite-strain Standard Linear Solid (SLS) constitutive model implemented in a quadratic finite element code and coupled to a high-order compressible Navier-Stokes solver through a boundary-fitted fluid-solid interface. The large non-linear mesh deformation is handled using an elliptic/poisson smoothening technique. Supra-glottal flow shows asymmetry in the flow, which in turn has a coupling effect on the motion of the VF. The fully compressible simulations gives direct insight into the sound produced as pressure distributions and the vocal fold deformation helps study the unsteady vortical flow resulting from the fluid-structure interaction along the full phonation cycle. Supported by the National Science Foundation (CAREER Award Number 1150439).

  6. Hydration thermodynamics beyond the linear response approximation

    Science.gov (United States)

    Raineri, Fernando O.

    2016-10-01

    The solvation energetics associated with the transformation of a solute molecule at infinite dilution in water from an initial state A to a final state B is reconsidered. The two solute states have different potentials energies of interaction, {{\\Psi}\\text{A}} and {{\\Psi}\\text{B}} , with the solvent environment. Throughout the A \\to B transformation of the solute, the solvation system is described by a Hamiltonian H≤ft(ξ \\right) that changes linearly with the coupling parameter ξ. By focusing on the characterization of the probability density {{\\wp}ξ}≤ft( y\\right) that the dimensionless perturbational solute-solvent interaction energy Y=β ≤ft({{\\Psi}\\text{B}}-{{\\Psi}\\text{A}}\\right) has numerical value y when the coupling parameter is ξ, we derive a hierarchy of differential equation relations between the ξ-dependent cumulant functions of various orders in the expansion of the appropriate cumulant generating function. On the basis of this theoretical framework we then introduce an inherently nonlinear solvation model for which we are able to find analytical results for both {{\\wp}ξ} ≤ft( y\\right) and for the solvation thermodynamic functions. The solvation model is based on the premise that there is an upper or a lower bound (depending on the nature of the interactions considered) to the amplitude of the fluctuations of Y in the solution system at equilibrium. The results reveal essential differences in behavior for the model when compared with the linear response approximation to solvation, particularly with regards to the probability density {{\\wp}ξ} ≤ft( y\\right) . The analytical expressions for the solvation properties show, however, that the linear response behavior is recovered from the new model when the room for the thermal fluctuations in Y is not restricted by the existence of a nearby bound. We compare the predictions of the model with the results from molecular dynamics computer simulations for aqueous solvation, in

  7. Development of experimental verification techniques for non-linear deformation and fracture.

    Energy Technology Data Exchange (ETDEWEB)

    Moody, Neville Reid; Bahr, David F. (Washington State University, Pullman, WA)

    2003-12-01

    This project covers three distinct features of thin film fracture and deformation in which the current experimental technique of nanoindentation demonstrates limitations. The first feature is film fracture, which can be generated either by nanoindentation or bulge testing thin films. Examples of both tests will be shown, in particular oxide films on metallic or semiconductor substrates. Nanoindentations were made into oxide films on aluminum and titanium substrates for two cases; one where the metal was a bulk (effectively single crystal) material and the other where the metal was a 1 pm thick film grown on a silica or silicon substrate. In both cases indentation was used to produce discontinuous loading curves, which indicate film fracture after plastic deformation of the metal. The oxides on bulk metals fractures occurred at reproducible loads, and the tensile stress in the films at fracture were approximately 10 and 15 GPa for the aluminum and titanium oxides respectively. Similarly, bulge tests of piezoelectric oxide films have been carried out and demonstrate film fracture at stresses of only 100's of MPa, suggesting the importance of defects and film thickness in evaluating film strength. The second feature of concern is film adhesion. Several qualitative and quantitative tests exist today that measure the adhesion properties of thin films. A relatively new technique that uses stressed overlayers to measure adhesion has been proposed and extensively studied. Delamination of thin films manifests itself in the form of either telephone cord or straight buckles. The buckles are used to calculate the interfacial fracture toughness of the film-substrate system. Nanoindentation can be utilized if more energy is needed to initiate buckling of the film system. Finally, deformation in metallic systems can lead to non-linear deformation due to 'bursts' of dislocation activity during nanoindentation. An experimental study to examine the structure of

  8. THIRD ORDER SHEAR DEFORMATION MODEL FOR LAMINATED SHELLS WITH FINITE ROTATIONS:FORMULATION AND CONSISTENT LINEARIZATION

    Institute of Scientific and Technical Information of China (English)

    Mohamed BALAH; Hamdan Naser AL-GHAMEDY

    2004-01-01

    The paper presents an approach for the formulation of general laminated shells based on a third order shear deformation theory. These shells undergo finite (unlimited in size) rotations and large overall motions but with small strains. A singularity-free parametrization of the rotation field is adopted. The constitutive equations, derived with respect to laminate curvilinear coordinates,are applicable to shell elements with an arbitrary number of orthotropic layers and where the material principal axes can vary from layer to layer. A careful consideration of the consistent linearization procedure pertinent to the proposed parametrization of finite rotations leads to symmetric tangent stiffness matrices. The matrix formulation adopted here makes it possible to implement the present formulation within the framework of the finite element method as a straightforward task.

  9. Extension of non-linear beam models with deformable cross sections

    Science.gov (United States)

    Sokolov, I.; Krylov, S.; Harari, I.

    2015-12-01

    Geometrically exact beam theory is extended to allow distortion of the cross section. We present an appropriate set of cross-section basis functions and provide physical insight to the cross-sectional distortion from linear elastostatics. The beam formulation in terms of material (back-rotated) beam internal force resultants and work-conjugate kinematic quantities emerges naturally from the material description of virtual work of constrained finite elasticity. The inclusion of cross-sectional deformation allows straightforward application of three-dimensional constitutive laws in the beam formulation. Beam counterparts of applied loads are expressed in terms of the original three-dimensional data. Special attention is paid to the treatment of the applied stress, keeping in mind applications such as hydrogel actuators under environmental stimuli or devices made of electroactive polymers. Numerical comparisons show the ability of the beam model to reproduce finite elasticity results with good efficiency.

  10. Deformation of the free surface of a conducting fluid in the magnetic field of current-carrying linear conductors

    Science.gov (United States)

    Zubarev, N. M.; Zubareva, O. V.

    2017-06-01

    The magnetic shaping problem is studied for the situation where a cylindrical column of a perfectly conducting fluid is deformed by the magnetic field of a system of linear current-carrying conductors. Equilibrium is achieved due to the balance of capillary and magnetic pressures. Two two-parametric families of exact solutions of the problem are obtained with the help of conformal mapping technique. In accordance with them, the column essentially deforms in the cross section up to its disintegration.

  11. Chemically tuned linear energy transfer dependent quenching in a deformable, radiochromic 3D dosimeter

    DEFF Research Database (Denmark)

    Høye, Ellen Marie; Skyt, Peter Sandegaard; Balling, Peter

    2017-01-01

    the observed quenching in proton beams. The dependency of dose response on linear energy transfer, as calculated through Monte Carlo simulations of the dosimeter, was investigated in 60 MeV proton beams. We found that the amount of quenching varied with the chemical composition: peak-to-plateau ratios (1cm...... chemical compositions of the dosimeter showed dose-rate dependency; however this was not dependent on the linear energy transfer. Track-structure theory was used to explain the observed quenching effects. In conclusion, this study shows that the silicone-based dosimeter has potential for use in measuring 3...

  12. Non-linear stochastic response of a shallow cable

    DEFF Research Database (Denmark)

    Larsen, Jesper Winther; Nielsen, Søren R.K.

    2004-01-01

    The paper considers the stochastic response of geometrical non-linear shallow cables. Large rain-wind induced cable oscillations with non-linear interactions have been observed in many large cable stayed bridges during the last decades. The response of the cable is investigated for a reduced two-degrees-of-freedom...

  13. Deformation Bands as Linear Elastic Fractures: Progress in Theory and Observation

    Science.gov (United States)

    Sternlof, K.; Pollard, D.

    2001-12-01

    Deformation bands (DBs) are thin, tabular, bounded features of highly localized shear and/or compaction that commonly occur as systematic and pervasive arrays in porous sandstone. They also constitute an active area of theoretical and experimental research into the compressive failure of granular materials. Based on our ongoing study of DBs in the field, we propose that they originate at stress concentrations and propagate as brittle fractures in a linear elastic medium. Furthermore, we suggest that individual DB morphology is largely dominated by the closing (anti-mode I) component of the displacement discontinuity accommodated. The notion of DBs as "anti-cracks" akin to pressure solution surfaces is not new. But close examination of real DB arrays within the unifying context of linear elastic fracture mechanics is needed to add depth and bring quantitative rigor to our understanding of the phenomenon. Thus, we are building a body of detailed data based on field observation and thin-section analysis to substantiate and expand our central hypothesis, while also laying the foundation for an effort to replicate realistic DB arrays using numerical modeling techniques. Our field effort focuses on the Jurassic Aztec Sandstone as exposed in and around the Valley of Fire State Park, Nevada. This area offers expansive and varied DB exposures within a thick and relatively consistent sequence of dune-dominated aeolian sandstone. We will present interim results, interpretations and conclusions specific to the elastic nature of DBs, in particular comparing our data to the three distinct fracture-tip models: the dislocation, and the crack with and without cohesive end zones. Each of these models predicts substantially different near-tip stress fields for the same material under the same remote loading conditions, leading to different expectations for basic DB shape, structure, and propagation and mechanical interaction behavior. These expectations will be compared to and judged

  14. Random Response of Linear Viscoelastic Systems under Random Excitation

    Institute of Scientific and Technical Information of China (English)

    张天舒; 方同

    2001-01-01

    A method of analyzing random response of linear viscoelastic systems under random excitation has been presented. The covariance matrices of random responses of a single-degree-freedom linear viscoelastic system subjected to stationary white noise and filtered white noise excitations have been obtained in closed form. For illustration, a numerical example has been included. It is observed that viscoelasticity has damping effect on the mean square random responses of the system, the higher is viscoelastic behavior, the higher the damping effect.

  15. Linearity of dose-response relationships for human carcinogenic exposures

    Energy Technology Data Exchange (ETDEWEB)

    Smith, A.H. (Univ. of California, Berkeley (USA))

    The shape of dose-response relationships is a critical factor in considering cancer risks for the work place and environmental exposure to carcinogens. Markedly different risk estimates result from assumptions of linearity versus sublinear and threshold assumptions. This paper presents evidence that the relationship between the relative risk of development of cancer and the dose rate to carcinogenic exposures is frequently linear with no evidence for thresholds. Dose-response relationships from four studies of asbestos and lung cancer were examined, all of which were consistent with a linear relationship. Analysis of the relationship between the relative risk of lung cancer and exposure to nickel in a smelter study, selected because of relatively good exposure data, demonstrated a close agreement with a linear relationship. The relationship between the level of arsenic in drinking wter and the prevalence of skin cancer also was linear for males in the highest prevalence age group in Taiwan, although there was some evidence of sublinearity for females and younger persons. Also, the relationships between the number of cigarettes smoked per day and the relative risk of lung cancer was very close to linear in many studies. The analysis of these and other studies involving human exposure to carcinogens provides empirical evidence for linearity when the response variable is a rate ratio measure, rather than a risk difference measure. Linearity in dose-response is biologically plausible, without invoking a one-hit model. Except in special circumstances. the epidemiological evidence supports linear extrapolation of cancer relative risks.

  16. Estimation of independent non-linear deformation modes for analysis of craniofacial malformations in crouzon mice

    DEFF Research Database (Denmark)

    Hansen, Michael Sass; Olafsdóttir, Hildur; Darvann, Tron Andre;

    2007-01-01

    of wild-type (normal) mice and Crouzon mice were investigated. We present for what we believe is the first time, a statistical deformation model based on independent component analysis (ICA). A set of deformation parameters for each mouse was calculated using a B-spline-based nonrigid registration. From...

  17. Modeling the Mechanical Response of In Vivo Human Skin Under a Rich Set of Deformations

    KAUST Repository

    Flynn, Cormac

    2011-03-11

    Determining the mechanical properties of an individual\\'s skin is important in the fields of pathology, biomedical device design, and plastic surgery. To address this need, we present a finite element model that simulates the skin of the anterior forearm and posterior upper arm under a rich set of three-dimensional deformations. We investigated the suitability of the Ogden and Tong and Fung strain energy functions along with a quasi-linear viscoelastic law. Using non-linear optimization techniques, we found material parameters and in vivo pre-stresses for different volunteers. The model simulated the experiments with errors-of-fit ranging from 13.7 to 21.5%. Pre-stresses ranging from 28 to 92 kPa were estimated. We show that using only in-plane experimental data in the parameter optimization results in a poor prediction of the out-of-plane response. The identifiability of the model parameters, which are evaluated using different determinability criteria, improves by increasing the number of deformation orientations in the experiments. © 2011 Biomedical Engineering Society.

  18. Linear optical response of finite systems using multishift linear system solvers.

    Science.gov (United States)

    Hübener, Hannes; Giustino, Feliciano

    2014-07-28

    We discuss the application of multishift linear system solvers to linear-response time-dependent density functional theory. Using this technique the complete frequency-dependent electronic density response of finite systems to an external perturbation can be calculated at the cost of a single solution of a linear system via conjugate gradients. We show that multishift time-dependent density functional theory yields excitation energies and oscillator strengths in perfect agreement with the standard diagonalization of the response matrix (Casida's method), while being computationally advantageous. We present test calculations for benzene, porphin, and chlorophyll molecules. We argue that multishift solvers may find broad applicability in the context of excited-state calculations within density-functional theory and beyond.

  19. Linear optical response of finite systems using multishift linear system solvers

    Energy Technology Data Exchange (ETDEWEB)

    Hübener, Hannes; Giustino, Feliciano [Department of Materials, University of Oxford, Oxford OX1 3PH (United Kingdom)

    2014-07-28

    We discuss the application of multishift linear system solvers to linear-response time-dependent density functional theory. Using this technique the complete frequency-dependent electronic density response of finite systems to an external perturbation can be calculated at the cost of a single solution of a linear system via conjugate gradients. We show that multishift time-dependent density functional theory yields excitation energies and oscillator strengths in perfect agreement with the standard diagonalization of the response matrix (Casida's method), while being computationally advantageous. We present test calculations for benzene, porphin, and chlorophyll molecules. We argue that multishift solvers may find broad applicability in the context of excited-state calculations within density-functional theory and beyond.

  20. LINEARIZING THE RESPONSE OF THE NSRL SYNCHRONOUS RECYCLING-INTEGRATORS.

    Energy Technology Data Exchange (ETDEWEB)

    ODDO, P.; RUSEK, A.; RUSSO, T.

    2005-05-16

    The Lawrence Berkeley National Laboratory (LBNL) designed recycling-integrators used for the NASA Space Radiation Laboratory (NSRL) dosimetry feature excellent linearity. However, switching transients in the balancing source add a duty-cycle dependence to the response that manifests as a non-linearity near mid-scale and a slope-change above mid-scale. The onset of this non-linearity limits the typical usable dynamic range. Measurements during a recent run showed that at higher intensities the recycling-integrators would operate in the non-linear region enough to exceed the desired tolerance and over count the dose. This report will show how a FPGA, which implements the scalars, was used to compensate the non-linearity allowing higher dose-rates by effectively doubling the dynamic range of the dosimetry system.

  1. Transient Response Model of Standing Wave Piezoelectric Linear Ultrasonic Motor

    Institute of Scientific and Technical Information of China (English)

    SHI Yunlai; CHEN Chao; ZHAO Chunsheng

    2012-01-01

    A transient response model for describing the starting and stopping characteristics of the standing wave piezoelectric linear ultrasonic motor was presented.Based on the contact dynamic model,the kinetic equation of the motor was derived.The starting and stopping characteristics of the standing wave piezoelectric linear ultrasonic motor according to different loads,contact stiffness and inertia mass were described and analyzed,respectively.To validate the transient response model,a standing wave piezoelectric linear ultrasonic motor based on in-plane modes was used to carry out the simulation and experimental study.The corresponding results showed that the simulation of the motor performances based on the proposed model agreed well with the experimental results.This model will helpful to improve the stepping characteristics and the control flexibility of the standing wave piezoelectric linear ultrasonic motor.

  2. Abrupt onset of tongue deformation and phase space response of ions in magnetically-confined plasmas

    Science.gov (United States)

    Ida, K.; Kobayashi, T.; Itoh, K.; Yoshinuma, M.; Tokuzawa, T.; Akiyama, T.; Moon, C.; Tsuchiya, H.; Inagaki, S.; Itoh, S.-I.

    2016-10-01

    An abrupt onset of the new tongue-shaped deformation of magnetic surface in magnetized plasmas, which was conjectured in since the 1960s but has not been observed, is experimentally identified just before an abrupt onset of a large-scale collapse event. Two novel properties of the event are identified. First, the transition of symmetry of perturbation (rather than a growth of linearly unstable MHD modes) was found to be a key for the onset of abrupt collapse, i.e., the transition of symmetry gives a new route to the collapse from stable state. Second, as a phase-space response of ions, the distortion from Maxwell-Boltzmann distribution of epithermal ions was observed for the first time.

  3. Abrupt onset of tongue deformation and phase space response of ions in magnetically-confined plasmas

    Science.gov (United States)

    Ida, K.; Kobayashi, T.; Itoh, K.; Yoshinuma, M.; Tokuzawa, T.; Akiyama, T.; Moon, C.; Tsuchiya, H.; Inagaki, S.; Itoh, S.-I.

    2016-01-01

    An abrupt onset of the new tongue-shaped deformation of magnetic surface in magnetized plasmas, which was conjectured in since the 1960s but has not been observed, is experimentally identified just before an abrupt onset of a large-scale collapse event. Two novel properties of the event are identified. First, the transition of symmetry of perturbation (rather than a growth of linearly unstable MHD modes) was found to be a key for the onset of abrupt collapse, i.e., the transition of symmetry gives a new route to the collapse from stable state. Second, as a phase-space response of ions, the distortion from Maxwell-Boltzmann distribution of epithermal ions was observed for the first time. PMID:27796370

  4. Note: A high dynamic range, linear response transimpedance amplifier.

    Science.gov (United States)

    Eckel, S; Sushkov, A O; Lamoreaux, S K

    2012-02-01

    We have built a high dynamic range (nine decade) transimpedance amplifier with a linear response. The amplifier uses junction-gate field effect transistors (JFETs) to switch between three different resistors in the feedback of a low input bias current operational amplifier. This allows for the creation of multiple outputs, each with a linear response and a different transimpedance gain. The overall bandwidth of the transimpedance amplifier is set by the bandwidth of the most sensitive range. For our application, we demonstrate a three-stage amplifier with transimpedance gains of approximately 10(9)Ω, 3 × 10(7)Ω, and 10(4)Ω with a bandwidth of 100 Hz.

  5. Testing Linear Models for Ability Parameters in Item Response Models

    NARCIS (Netherlands)

    Glas, Cees A.W.; Hendrawan, Irene

    2005-01-01

    Methods for testing hypotheses concerning the regression parameters in linear models for the latent person parameters in item response models are presented. Three tests are outlined: A likelihood ratio test, a Lagrange multiplier test and a Wald test. The tests are derived in a marginal maximum like

  6. Conceptual DFT: chemistry from the linear response function.

    Science.gov (United States)

    Geerlings, Paul; Fias, Stijn; Boisdenghien, Zino; De Proft, Frank

    2014-07-21

    Within the context of reactivity descriptors known in conceptual DFT, the linear response function (χ(r,r')) remained nearly unexploited. Although well known, in its time dependent form, in the solid state physics and time-dependent DFT communities the study of the "chemistry" present in the kernel was, until recently, relatively unexplored. The evaluation of the linear response function as such and its study in the time independent form are highlighted in the present review. On the fundamental side, the focus is on the approaches of increasing complexity to compute and represent χ(r,r'), its visualisation going from plots of the unintegrated χ(r,r') to an atom condensed matrix. The study on atoms reveals its physical significance, retrieving atomic shell structure, while the results on molecules illustrate that a variety of chemical concepts are retrieved: inductive and mesomeric effects, electron delocalisation, aromaticity and anti-aromaticity, σ and π aromaticity,…. The applications show that the chemistry of aliphatic (saturated and unsaturated) chains, saturated and aromatic/anti-aromatic rings, organic, inorganic or metallic in nature, can be retrieved via the linear response function, including the variation of the electronic structure of the reagents along a reaction path. The connection of the linear response function with the concept of nearsightedness and the alchemical derivatives is also highlighted.

  7. Linear-response thermal time-dependent density functional theory

    CERN Document Server

    Pribram-Jones, Aurora; Burke, Kieron

    2015-01-01

    The van Leeuwen proof of linear-response time-dependent density functional theory (TDDFT) is generalized to thermal ensembles. This allows generalization to finite temperatures of the Gross-Kohn relation, the exchange-correlation kernel of TDDFT, and fluctuation dissipation theorem for DFT. This produces a natural method for generating new thermal exchange-correlation (XC) approximations.

  8. Computational analysis of linear friction welding process and micromechanical modeling of deformation behavior for medium carbon steel

    Institute of Scientific and Technical Information of China (English)

    杨夏炜; 李文亚; 马铁军

    2015-01-01

    Finite element simulation of linear friction welding (LFW) medium carbon steel was carried out using the ABAQUS software. A two-dimensional (2D) coupled thermo-mechanical model was established. First, the temperature fields of medium carbon steel during LFW process were investigated. And then, the Mises stress and the 1st, 2nd and 3rd principal stresses fields’ evolution of the steel during LFW process were studied. The deformation behavior of LFW carbon steel was analyzed by using micromechanics model based on ABAQUS with Python code. The Lode parameter was expressed using the Mohr stress circle and it was investigated in detail.

  9. Nucleus pulposus deformation in response to lumbar spine lateral flexion: an in vivo MRI investigation.

    Science.gov (United States)

    Fazey, Peter J; Takasaki, Hiroshi; Singer, Kevin P

    2010-07-01

    Whilst there are numerous studies examining aspects of sagittal plane motion in the lumbar spine, few consider coronal plane range of motion and there are no in vivo reports of nucleus pulposus (NP) displacement in lateral flexion. This study quantified in vivo NP deformation in response to side flexion in healthy volunteers. Concomitant lateral flexion and axial rotation range were also examined to evaluate the direction and extent of NP deformation. Axial T2- and coronal T1-weighted magnetic resonance images (MRI) were obtained from 21 subjects (mean age, 24.8 years) from L1 to S1 in the neutral and left laterally flexed position. Images were evaluated for intersegmental ranges of lateral flexion and axial rotation. A novel methodology derived linear pixel samples across the width of the disc from T2 images, from which the magnitude and direction of displacement of the NP was determined. This profiling technique represented the relative hydration pattern within the disc. The NP was displaced away from the direction of lateral flexion in 95/105 discs (p < 0.001). The extent of NP displacement was associated strongly with lateral flexion at L2-3 (p < 0.01). The greatest range of lateral flexion occurred at L2-3, L3-4 and L4-5. Small intersegmental ranges of axial rotation occurred at all levels, but were not associated with NP displacement. The direction of NP deformation was highly predictable in laterally flexed healthy lumbar spines; however, the magnitude of displacement was not consistent with the degree of intersegmental lateral flexion or rotation.

  10. Optimal approximation of linear systems by artificial immune response

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    This paper puts forward a novel artificial immune response algorithm for optimal approximation of linear systems. A quaternion model of artificial immune response is proposed for engineering computing. The model abstracts four elements, namely, antigen, antibody, reaction rules among antibodies, and driving algorithm describing how the rules are applied to antibodies, to simulate the process of immune response. Some reaction rules including clonal selection rules, immunological memory rules and immune regulation rules are introduced. Using the theorem of Markov chain, it is proofed that the new model is convergent. The experimental study on the optimal approximation of a stable linear system and an unstable one show that the approximate models searched by the new model have better performance indices than those obtained by some existing algorithms including the differential evolution algorithm and the multi-agent genetic algorithm.

  11. Dynamic Response of Linear Mechanical Systems Modeling, Analysis and Simulation

    CERN Document Server

    Angeles, Jorge

    2012-01-01

    Dynamic Response of Linear Mechanical Systems: Modeling, Analysis and Simulation can be utilized for a variety of courses, including junior and senior-level vibration and linear mechanical analysis courses. The author connects, by means of a rigorous, yet intuitive approach, the theory of vibration with the more general theory of systems. The book features: A seven-step modeling technique that helps structure the rather unstructured process of mechanical-system modeling A system-theoretic approach to deriving the time response of the linear mathematical models of mechanical systems The modal analysis and the time response of two-degree-of-freedom systems—the first step on the long way to the more elaborate study of multi-degree-of-freedom systems—using the Mohr circle Simple, yet powerful simulation algorithms that exploit the linearity of the system for both single- and multi-degree-of-freedom systems Examples and exercises that rely on modern computational toolboxes for both numerical and symbolic compu...

  12. Development of experimental verification techniques for non-linear deformation and fracture on the nanometer scale.

    Energy Technology Data Exchange (ETDEWEB)

    Moody, Neville Reid; Bahr, David F.

    2005-11-01

    This work covers three distinct aspects of deformation and fracture during indentations. In particular, we develop an approach to verification of nanoindentation induced film fracture in hard film/soft substrate systems; we examine the ability to perform these experiments in harsh environments; we investigate the methods by which the resulting deformation from indentation can be quantified and correlated to computational simulations, and we examine the onset of plasticity during indentation testing. First, nanoindentation was utilized to induce fracture of brittle thin oxide films on compliant substrates. During the indentation, a load is applied and the penetration depth is continuously measured. A sudden discontinuity, indicative of film fracture, was observed upon the loading portion of the load-depth curve. The mechanical properties of thermally grown oxide films on various substrates were calculated using two different numerical methods. The first method utilized a plate bending approach by modeling the thin film as an axisymmetric circular plate on a compliant foundation. The second method measured the applied energy for fracture. The crack extension force and applied stress intensity at fracture was then determined from the energy measurements. Secondly, slip steps form on the free surface around indentations in most crystalline materials when dislocations reach the free surface. Analysis of these slip steps provides information about the deformation taking place in the material. Techniques have now been developed to allow for accurate and consistent measurement of slip steps and the effects of crystal orientation and tip geometry are characterized. These techniques will be described and compared to results from dislocation dynamics simulations.

  13. Covalent bonding from alchemical linear response density functional theory

    CERN Document Server

    Chang, K Y Samuel; Ramakrishnan, Raghunathan; von Lilienfeld, O Anatole

    2015-01-01

    We assess the predictive accuracy of linear response based estimates of changes in covalent bonding due to linear alchemical interpolations among molecules. We have investigated single bonds to hydrogen, as well as single, double, and triple bonds between main-group elements, occurring in small iso-electronic molecular spaces with atomic elements drawn from rows 2-3 in the $p$-block of the periodic table. Numerical evidence suggests that first order estimates of bonding potentials can achieve chemical accuracy if the alchemical interpolation connects molecules containing late elements in the periodic table (3$^{rd}$ and 4$^{th}$ row) and identical number of atoms and molecular geometries. For these interpolations, changes in bonding potential are near-linear in the coupling parameter, resulting in accurate Hellmann-Feynman predictions. Second order estimates for such interpolations yield worse predictions. The predictions become substantially worse if initial and final molecules differ not only in composition...

  14. ELECTRO-THERMAL EFFECTS AND DEFORMATION RESPONSE OF CARBON FIBER MAT CEMENT BEAMS

    Institute of Scientific and Technical Information of China (English)

    ZhuSirong; LiZhuoqiu; SongXianhui

    2003-01-01

    A carbon fiber mat is a sheet composed of intercrossing short carbon fibers, which has more stable and lower electrical resistivity compared with dispersed short carbon fiber mixed in cement. Thereby carbon fiber mat cement could exhibit obvious electro-thermal effect. When electrified, the temperature of composite structures made up of cement mortar and carbon fiber mat will rise rapidly. If the temperature field is not uniform, temperature difference will cause structures to deform, which can be used to adjust the deformation of structures. The temperature field and deformation response driven by the electro-thermal effects of a type of carbon fiber mat cement beams are studied. Firstly, the temperature and deformation responses are studied using theories of thermal conduction and elasticity. Secondly, experimental results are given to verify the theoretical solution. These two parts lay the foundation for temperature and deformation adjustment.

  15. Cosmological Horizon Modes and Linear Response in de Sitter Spacetime

    CERN Document Server

    Anderson, Paul R; Mottola, Emil

    2009-01-01

    Linearized fluctuations of quantized matter fields and the spacetime geometry around de Sitter space are considered in the case that the matter fields are conformally invariant. Taking the unperturbed state of the matter to be the de Sitter invariant Bunch-Davies state, the linear variation of the stress tensor about its self-consistent mean value serves as a source for fluctuations in the geometry through the semi-classical Einstein equations. This linear response framework is used to investigate both the importance of quantum backreaction and the validity of the semi-classical approximation in cosmology. The full variation of the stress tensor, delta T^a_b contains two kinds of terms: (1) those that depend explicitly upon the linearized metric variation delta g_{cd} through the [T^a_b, T^{cd}] causal response function; and (2) state dependent variations, independent of delta g_{cd}. For perturbations of the first kind, the criterion for the validity of the semi-classical approximation in de Sitter space is ...

  16. Response to pediatric physical therapy in infants with positional preference and skull deformation

    NARCIS (Netherlands)

    Wijk, R.M. van; Pelsma, M.; Groothuis-Oudshoorn, C.G.; IJzerman, M.J.; Vlimmeren, L.A. van; Boere-Boonekamp, M.M.

    2014-01-01

    BACKGROUND: Pediatric physical therapy seems to reduce skull deformation in infants with positional preference. However, not all infants show improvement. OBJECTIVE: The study objective was to determine which infant and parent characteristics were related to responses to pediatric physical therapy

  17. Linear density response function in the projector augmented wave method

    DEFF Research Database (Denmark)

    Yan, Jun; Mortensen, Jens Jørgen; Jacobsen, Karsten Wedel;

    2011-01-01

    We present an implementation of the linear density response function within the projector-augmented wave method with applications to the linear optical and dielectric properties of both solids, surfaces, and interfaces. The response function is represented in plane waves while the single......-particle eigenstates can be expanded on a real space grid or in atomic-orbital basis for increased efficiency. The exchange-correlation kernel is treated at the level of the adiabatic local density approximation (ALDA) and crystal local field effects are included. The calculated static and dynamical dielectric...... functions of Si, C, SiC, AlP, and GaAs compare well with previous calculations. While optical properties of semiconductors, in particular excitonic effects, are generally not well described by ALDA, we obtain excellent agreement with experiments for the surface loss function of graphene and the Mg(0001...

  18. Linear response at the 4-component relativistic level

    DEFF Research Database (Denmark)

    Saue, T.; Jensen, Hans Jørgen Aagaard

    2003-01-01

    The theory, implementation, and application of linear response at the 4-component relativistic closed-shell Hartree-Fock level based on the concept of quasienergy and time averaging are reported. As such, an efficient AO-driven algorithm is obtained by assigning specific Hermiticity and time...... reversal symmetry to the trial vectors used in the solution of the reduced response equations. The given implementation has a quite general structure and thereby allows the calculation of a wide range of second-order properties such as polarizabilities, magnetizabilities, as well as NMR parameters....

  19. Non-linear mass-spring system for large soft tissue deformations modeling

    CERN Document Server

    Nikolaev, Sergei

    2014-01-01

    Implant placement under soft tissues operation is described. In this operation tissues can reach such deformations that nonlinear properties are appeared. A mass-spring model modification for modeling nonlinear tissue operation is developed. A method for creating elasticity module using splines is described. For Poisson ratio different stiffness for different types of springs in cubic grid is used. For stiffness finding an equation system that described material tension is solved. The model is verified with quadratic sample tension experiment. These tests show that sample tension under external forces is equal to defined nonlinear elasticity module. The accuracy of Poisson ratio modeling is thirty five percent that is better the results of available ratio modeling method.

  20. Optical linear response function with linear and diagonal quadratic electron-vibration coupling in mixed quantum-classical systems.

    Science.gov (United States)

    Toutounji, Mohamad

    2004-08-01

    Optical linear response function of linearly and quadratically coupled mixed quantum-classical condensed phase systems is derived. The linear response function is derived using Kapral's formalism of statistical mechanics in mixed quantum-classical systems. Our mixed quantum-classical linear dipole moment correlation function J(t) is compared with the full quantum J(t) [Y. J. Yan and S. Mukamel, J. Chem. Phys. 85, 5908 (1986)] in the high temperature limit. Model calculations and discussion of our results are presented. Various formulas of Franck-Condon factors for both linear and quadratic coupling are discussed. (c) 2004 American Institute of Physics.

  1. Non-Linear Dynamic Deformation of a Piezothermoelastic Laminate with Feedback Control System

    Directory of Open Access Journals (Sweden)

    Masayuki Ishihara

    2014-03-01

    Full Text Available We study the control of free vibration with large amplitude in a piezothermoelastic laminated beam subjected to a uniform temperature with a feedback control system. The analytical model is the symmetrically cross-ply laminated beam composed of the elastic and piezoelectric layers. On the basis of the von Kármán strain and the classical laminate theory, the governing equations for the dynamic behavior are derived. The dynamic behavior is detected by the electric current in the sensor layer through the direct piezoelectric effect. The electric voltage with the magnitude of the current multiplied by the gain is applied to the actuator layer to constitute a feedback control system. The governing equations are reduced by the Galerkin method to a Liénard equation with respect to the representative deflection, and the equation is found to be dependent on the gain and the configuration of the actuator. By introducing the Liénard's phase plane, the equation is analyzed geometrically, and the essential characteristics of the beam and stabilization of the dynamic deformation are demonstrated.

  2. Assessment of Two Analytical Methods in Solving the Linear and Nonlinear Elastic Beam Deformation Problems

    DEFF Research Database (Denmark)

    Barari, Amin; Ganjavi, B.; Jeloudar, M. Ghanbari

    2010-01-01

    Purpose – In the last two decades with the rapid development of nonlinear science, there has appeared ever-increasing interest of scientists and engineers in the analytical techniques for nonlinear problems. This paper considers linear and nonlinear systems that are not only regarded as general...... and fluid mechanics. Design/methodology/approach – Two new but powerful analytical methods, namely, He's VIM and HPM, are introduced to solve some boundary value problems in structural engineering and fluid mechanics. Findings – Analytical solutions often fit under classical perturbation methods. However...

  3. Linear response to long wavelength fluctuations using curvature simulations

    CERN Document Server

    Baldauf, Tobias; Senatore, Leonardo; Zaldarriaga, Matias

    2015-01-01

    We study the local response to long wavelength fluctuations in cosmological $N$-body simulations, focusing on the matter and halo power spectra, halo abundance and non-linear transformations of the density field. The long wavelength mode is implemented using an effective curved cosmology and a mapping of time and distances. The method provides an alternative, most probably more precise, way to measure the isotropic halo biases. Limiting ourselves to the linear case, we find generally good agreement between the biases obtained from the curvature method and the traditional power spectrum method at the level of a few percent. We also study the response of halo counts to changes in the variance of the field and find that the slope of the relation between the responses to density and variance differs from the naive derivation assuming a universal mass function by 18%. This has implications for measurements of the amplitude of local non-Gaussianity using scale dependent bias. We also analyze the halo power spectrum...

  4. Symmetry-imposed shape of linear response tensors

    Science.gov (United States)

    Seemann, M.; Ködderitzsch, D.; Wimmer, S.; Ebert, H.

    2015-10-01

    A scheme suggested in the literature to determine the symmetry-imposed shape of linear response tensors is revised and extended to allow for the treatment of more complex situations. The extended scheme is applied to discuss the shape of the spin conductivity tensor for all magnetic space groups. This allows in particular investigating the character of longitudinal as well as transverse spin transport for arbitrary crystal structure and magnetic order that give rise, e.g., to the spin Hall, Nernst, and the spin-dependent Seebeck effects.

  5. The nonconforming linear strain tetrahedron for a large deformation elasticity problem

    Science.gov (United States)

    Hansbo, Peter; Larsson, Fredrik

    2016-12-01

    In this paper we investigate the performance of the nonconforming linear strain tetrahedron element introduced by Hansbo (Comput Methods Appl Mech Eng 200(9-12):1311-1316, 2011; J Numer Methods Eng 91(10):1105-1114, 2012). This approximation uses midpoints of edges on tetrahedra in three dimensions with either point continuity or mean continuity along edges of the tetrahedra. Since it contains (rotated) bilinear terms it performs substantially better than the standard constant strain element in bending. It also allows for under-integration in the form of one point Gauss integration of volumetric terms in near incompressible situations. We combine under-integration of the volumetric terms with houglass stabilization for the isochoric terms.

  6. The nonconforming linear strain tetrahedron for a large deformation elasticity problem

    Science.gov (United States)

    Hansbo, Peter; Larsson, Fredrik

    2016-08-01

    In this paper we investigate the performance of the nonconforming linear strain tetrahedron element introduced by Hansbo (Comput Methods Appl Mech Eng 200(9-12):1311-1316, 2011; J Numer Methods Eng 91(10):1105-1114, 2012). This approximation uses midpoints of edges on tetrahedra in three dimensions with either point continuity or mean continuity along edges of the tetrahedra. Since it contains (rotated) bilinear terms it performs substantially better than the standard constant strain element in bending. It also allows for under-integration in the form of one point Gauss integration of volumetric terms in near incompressible situations. We combine under-integration of the volumetric terms with houglass stabilization for the isochoric terms.

  7. Linear response theory for magnon transport in ferromagnetic insulators

    Science.gov (United States)

    Murakami, Shuichi; Matsumoto, Ryo

    2012-02-01

    We study transverse response of magnons in ferromagnetic insulators within linear response theory. In analogy with the corresponding theory for electrons [1], magnon transverse response is described, including the Hall effect, Nernst effect, and thermal Hall effect. As is also the case for electrons [1], the response functions for magnons consist of the Kubo-formula term, and the term corresponding to the orbital angular momentum. We can rewrite the response functions in terms of the Berry curvature in momentum space [2]. We apply this theory to the (quantum-mechanical) magnons and to the classical magnetostatic waves. For the magnetostatic waves, the eigenmodes are given by a generalized eigenvalue problem, giving rise to the special form of the Berry curvature [2]. We explain various properties of this Berry curvature for the generalized eigenvalue problem, and discuss its implications for the physical properties of magnetostatic modes. [1] L. Smrcka and P. Streda, J. Phys. C, 10, 2153 (1977); H. Oji, P. Streda, Phys. Rev. B 31, 7291 (1985); [2] R. Matsumoto and S. Murakami, Phys. Rev. Lett. 106, 197202 (2011); Phys. Rev. B 84, 184406 (2011).

  8. The Overall Response of Composite Materials Undergoing Large Elastic Deformations

    Science.gov (United States)

    1990-06-13

    by Willis (1990), and the new results are found to be superior . In particular, the physically unrealistic discontinuous behavior of Willis’ model...6, 1990. Instituto de Investigaciones en Matematicas Applicadas y en Systemas, Universidad Nacional Autonoma de Mexico, Mexico City, July 1990...energy. O. the other hand, the nonlinear bounds corresponding to the Hashin- Shtrikman bounds for the linear isotropic composite turn out to be superior

  9. Projected-deformed wavefunctions with central Jastrow and linear state-dependent correlations for {sup 8}Be and {sup 12}C

    Energy Technology Data Exchange (ETDEWEB)

    Buenda, E.; Galvez, F.J.; Praena, J. [Departamento de Fisica Moderna, Facultad de Ciencias, Universidad de Granada, Granada (Spain); Sarsa, A. [International School for Advanced Studies, SISSA, Trieste (Italy)

    2001-11-01

    Trial wavefunctions including angular momentum projection and deformations, with linearized state-dependent and central Jastrow-type correlations are used to study the ground state rotational band of both {sup 8}Be and {sup 12}C nuclei. The competition between deformations, central Jastrow-type correlations and operatorial linear correlations is systematically analysed on different properties such as the energy, the square root mean radii, and transition amplitudes of the rotational band. A study of the one- and two-body spatial ground state densities is also carried out. All the matrix elements have been calculated by performing Monte Carlo simulations. (author)

  10. Geyser periodicity and the response of geysers to deformation

    Science.gov (United States)

    Ingebritsen, S.E.; Rojstaczer, S.A.

    1996-01-01

    Numerical simulations of multiphase fluid and heat transport through a porous medium define combinations of rock properties and boundary conditions which lead to geyser-like periodic discharge. Within the rather narrow range of conditions that allow geyser-like behavior, eruption frequency and discharge are highly sensitive to the intrinsic permeabilities of the geyser conduit and the surrounding rock matrix, to the relative permeability functions assumed, and to pressure gradients in the matrix. In theory, heats pipes (concomitant upward flow of steam and downward flow of liquid) can exist under similar conditions, but our simulations suggest that the periodic solution is more stable. Simulated time series of geyser discharge are chaotic, but integrated quantities such as eruption frequency and mass discharge per eruption are free of chaos. These results may explain the observed sensitivity of natural geysers to small strains such as those caused by remote earthquakes, if ground motion is sufficient to induce permeability changes. Changes in geyser behavior caused by minor preseismic deformation, periodic surface loading, and Earth tides are more difficult to explain in the context of our current model. Copyright 1996 by the American Geophysical Union.

  11. Direct calculation of the linear thermal expansion coefficients of MoS2 via symmetry-preserving deformations

    Science.gov (United States)

    Gan, Chee Kwan; Liu, Yu Yang Fredrik

    2016-10-01

    Using density-functional perturbation theory and the Grüneisen formalism, we directly calculate the linear thermal expansion coefficients (TECs) of a hexagonal bulk system MoS2 in the crystallographic a and c directions. The TEC calculation depends critically on the evaluation of a temperature-dependent quantity Ii(T ) , which is the integral of the product of heat capacity and Γi(ν ) , of frequency ν and strain type i , where Γi(ν ) is the phonon density of states weighted by the Grüneisen parameters. We show that to determine the linear TECs we may use minimally two uniaxial strains in the z direction and either the x or y direction. However, a uniaxial strain in either the x or y direction drastically reduces the symmetry of the crystal from a hexagonal one to a base-centered orthorhombic one. We propose to use an efficient and accurate symmetry-preserving biaxial strain in the x y plane to derive the same result for Γ (ν ) . We highlight that the Grüneisen parameter associated with a biaxial strain may not be the same as the average of Grüneisen parameters associated with two separate uniaxial strains in the x and y directions due to possible preservation of degeneracies of the phonon modes under a biaxial deformation. Large anisotropy of TECs is observed where the linear TEC in the c direction is about 1.8 times larger than that in the a or b direction at high temperatures. Our theoretical TEC results are compared with experiment. The symmetry-preserving approach adopted here may be applied to a broad class of two lattice-parameter systems such as hexagonal, trigonal, and tetragonal systems, which allows many complicated systems to be treated on a first-principles level.

  12. Linear and nonlinear optical response of spherical anisotropic semiconductor microcrystallites

    Science.gov (United States)

    Ramaniah, Lavanya M.; Nair, Selvakumar V.; Rustagi, Kailash C.

    1989-12-01

    We present a phenomenological theory of the linear and nonlinear optical properties associated with the Fröhlich resonances of an optically anisotropic, spherical semiconductor crystallite. Using the Maxwell-Garnett approach, we calculate the effective dielectric function of a composite medium containing such crystallites. To study the effect of anisotropy, we take CdS and CdSe quantum dots as examples for the inclusions, and use a two-resonance model for the dielectric function. Even for randomly oriented inclusions, the Fröhlich resonances split as a result of anisotropic local-field corrections. At higher laser intensities, absorption saturation leads to bistability or tristability in the optical response of individual crystallites, while the response of the composite medium with randomly oriented inclusions shows multistability, with many intermediate branches. The nonlinear response of such a composite medium also exhibits a new kind of orientation-induced broadening of resonances. We also find that tristability is possible in another kind of inhomogeneous material, viz., a composite medium containing two types of isotropic spherical crystallites.

  13. How linear features alter predator movement and the functional response.

    KAUST Repository

    McKenzie, Hannah W

    2012-01-18

    In areas of oil and gas exploration, seismic lines have been reported to alter the movement patterns of wolves (Canis lupus). We developed a mechanistic first passage time model, based on an anisotropic elliptic partial differential equation, and used this to explore how wolf movement responses to seismic lines influence the encounter rate of the wolves with their prey. The model was parametrized using 5 min GPS location data. These data showed that wolves travelled faster on seismic lines and had a higher probability of staying on a seismic line once they were on it. We simulated wolf movement on a range of seismic line densities and drew implications for the rate of predator-prey interactions as described by the functional response. The functional response exhibited a more than linear increase with respect to prey density (type III) as well as interactions with seismic line density. Encounter rates were significantly higher in landscapes with high seismic line density and were most pronounced at low prey densities. This suggests that prey at low population densities are at higher risk in environments with a high seismic line density unless they learn to avoid them.

  14. Hall Viscosity I: Linear Response Theory for Viscosity

    Science.gov (United States)

    Bradlyn, Barry; Goldstein, Moshe; Read, Nicholas

    2012-02-01

    In two dimensional systems with broken time-reversal symmetry, there can exist a non-dissipative viscosity coefficient [1,2,3]. This Hall viscosity is similar in nature to the non-dissipative Hall conductivity. In order to investigate this phenomenon further, we develop a linear response formalism for viscosity. We derive a Kubo formula for the frequency dependent viscosity tensor in the long wavelength limit. We compute the viscosity tensor for the free electron gas, integer quantum Hall systems, and two-dimensional paired superfluids. In the zero frequency limit, we show how the known results [3,4] for the Hall viscosity are recovered.[4pt] [1] J. Avron, R. Seiler, and P. Zograf, Phys. Rev. Lett. 75, 697 (1995).[0pt] [2] P. Levay, J. Math. Phys. 36, 2792 (1995).[0pt] [3] N. Read, Phys. Rev. B 79, 045308 (2009).[0pt] [4] N. Read and E. Rezayi, Phys. Rev. B 84, 085316 (2011).

  15. Mechanical Response of DNA–Nanoparticle Crystals to Controlled Deformation

    Science.gov (United States)

    2016-01-01

    The self-assembly of DNA-conjugated nanoparticles represents a promising avenue toward the design of engineered hierarchical materials. By using DNA to encode nanoscale interactions, macroscale crystals can be formed with mechanical properties that can, at least in principle, be tuned. Here we present in silico evidence that the mechanical response of these assemblies can indeed be controlled, and that subtle modifications of the linking DNA sequences can change the Young’s modulus from 97 kPa to 2.1 MPa. We rely on a detailed molecular model to quantify the energetics of DNA–nanoparticle assembly and demonstrate that the mechanical response is governed by entropic, rather than enthalpic, contributions and that the response of the entire network can be estimated from the elastic properties of an individual nanoparticle. The results here provide a first step toward the mechanical characterization of DNA–nanoparticle assemblies, and suggest the possibility of mechanical metamaterials constructed using DNA. PMID:27725959

  16. Measurement of the force–displacement response of in vivo human skin under a rich set of deformations

    KAUST Repository

    Flynn, Cormac

    2011-06-01

    The non-linear, anisotropic, and viscoelastic properties of human skin vary according to location on the body, age, and individual. The measurement of skin\\'s mechanical properties is important in several fields including medicine, cosmetics, and forensics. In this study, a novel force-sensitive micro-robot applied a rich set of three-dimensional deformations to the skin surface of different areas of the arms of 20 volunteers. The force-displacement response of each area in different directions was measured. All tested areas exhibited a non-linear, viscoelastic, and anisotropic force-displacement response. There was a wide quantitative variation in the stiffness of the response. For the right anterior forearm, the ratio of the maximum probe reaction force to maximum probe displacement ranged from 0.44Nmm-1 to 1.45Nmm-1. All volunteers exhibited similar qualitative anisotropic characteristics. For the anterior right forearm, the stiffest force-displacement response was when the probe displaced along the longitudinal axis of the forearm. The response of the anterior left forearm was stiffest in a direction 20° to the longitudinal axis of the forearm. The posterior upper arm was stiffest in a direction 90° to the longitudinal axis of the arm. The averaged posterior upper arm response was less stiff than the averaged anterior forearm response. The maximum probe force at 1.3mm probe displacement was 0.69N for the posterior upper arm and 1.1N for the right anterior forearm. The average energy loss during the loading-unloading cycle ranged from 11.9% to 34.2%. This data will be very useful for studying the non-linear, anisotropic, and viscoelastic behaviour of skin and also for generating material parameters for appropriate constitutive models. © 2011 IPEM.

  17. DIRECT SPECTRUM ANALYSIS OF ANELASTIC DEFORMATION RESPONSE DURING STRUCTURAL RELAXATION OF AMORPHOUS METALS

    NARCIS (Netherlands)

    CSACH, K; Ocelik, Vaclav; MISKUF, J; BENGUS, VZ; DUHAJ, P

    1994-01-01

    Direct relaxation time spectrum analysis method has been successfully used to observe and. to study changes in the kinetics of isothermal anelastic deformation response of soft magnetic metallic glass Fe40Ni40B20 during structural relaxation. Computed relaxation time spectra contain three or four qu

  18. Response to pediatric physical therapy in infants with positional preference and skull deformation

    NARCIS (Netherlands)

    Wijk, R.M. van; Pelsma, M.; Groothuis-Oudshoorn, C.G.; IJzerman, M.J.; Vlimmeren, L.A. van; Boere-Boonekamp, M.M.

    2014-01-01

    BACKGROUND: Pediatric physical therapy seems to reduce skull deformation in infants with positional preference. However, not all infants show improvement. OBJECTIVE: The study objective was to determine which infant and parent characteristics were related to responses to pediatric physical therapy i

  19. Effect of Passive Pile on 3D Ground Deformation and on Active Pile Response

    OpenAIRE

    Bingxiang Yuan; Rui Chen; Jun Teng; Tao Peng; Zhongwen Feng

    2014-01-01

    Using a series of model tests, this study investigated the effect of a passive pile on 3D ground deformation around a laterally loaded pile and on that laterally loaded pile’s response in sand. The active pile head was subjected to lateral loads, and the passive pile was arranged in front of the active pile. In the model tests, the distance between the two pile centers was set to zero (i.e., a single pile test), 2.5, 4, and 6 times the pile width (B). The 3D ground surface deformations around...

  20. Synergy effects in the deformation response of thermodynamically open metal-hydrogen systems

    Energy Technology Data Exchange (ETDEWEB)

    Spivak, L V [Perm State University, Perm (Russian Federation)

    2008-09-30

    This paper reviews how polycrystalline and amorphous metals respond to the combined effect of a nonuniform force field and a high-intensity hydrogen (deuterium) diffusion flow. It is shown that deformation effects in such thermodynamically open systems result from phase transitions occurring due to changes in the hydrogen (deuterium) concentration. The necessary and sufficient criteria for observing such synergy effects are formulated. It is shown that the deformation response in a nonuniform stress field is a very sensitive means for indicating first and second-order structural phase transitions in metal-hydrogen systems. (reviews of topical problems)

  1. Nonlinear viscoelastic response of highly filled elastomers under multiaxial finite deformation

    Science.gov (United States)

    Peng, Steven T. J.; Landel, Robert F.

    1990-01-01

    A biaxial tester was used to obtain precise biaxial stress responses of highly filled, high strain capability elastomers. Stress-relaxation experiments show that the time-dependent part of the relaxation response can be reasonably approximated by a function which is strain and biaxiality independent. Thus, isochronal data from the stress-relaxation curves can be used to determine the stored energy density function. The complex behavior of the elastomers under biaxial deformation may be caused by dewetting.

  2. Linear response theory an analytic-algebraic approach

    CERN Document Server

    De Nittis, Giuseppe

    2017-01-01

    This book presents a modern and systematic approach to Linear Response Theory (LRT) by combining analytic and algebraic ideas. LRT is a tool to study systems that are driven out of equilibrium by external perturbations. In particular the reader is provided with a new and robust tool to implement LRT for a wide array of systems. The proposed formalism in fact applies to periodic and random systems in the discrete and the continuum. After a short introduction describing the structure of the book, its aim and motivation, the basic elements of the theory are presented in chapter 2. The mathematical framework of the theory is outlined in chapters 3–5: the relevant von Neumann algebras, noncommutative $L^p$- and Sobolev spaces are introduced; their construction is then made explicit for common physical systems; the notion of isopectral perturbations and the associated dynamics are studied. Chapter 6 is dedicated to the main results, proofs of the Kubo and Kubo-Streda formulas. The book closes with a chapter about...

  3. A noble refractive optical scanner with linear response

    Science.gov (United States)

    Mega, Yair J.; Lai, Zhenhua; DiMarzio, Charles A.

    2013-03-01

    Many applications in various fields of science and engineering use steered optical beam systems. Currently, many methods utilize mirrors in order to steer the beam. However, this approach is an off-axis solution, which normally increases the total size of the system as well as its error and complexity. Other methods use a "Risely Prisms" based solution, which is on-axis solution, however it poses some difficulties from an engineering standpoint, and therefore isn't widely used. We present here a novel technique for steering a beam on its optical axis with a linear deflection response. We derived the formulation for the profile required of the refractive optical component necessary for preforming the beam steering. The functionality of the device was simulated analytically using Matlab, as well as using a ray-tracing software, Zemax, and showed agreement with the analytical model. An optical element was manufactured based on the proposed design and the device was tested. The results show agreement with our hypothesis. We also present some proposed geometries of the several other devices, all based on the same concept, which can be used for higher performance applications such as two-dimensional scanner, video rate scanner etc.

  4. Response to pediatric physical therapy in infants with positional preference and skull deformation.

    Science.gov (United States)

    van Wijk, Renske M; Pelsma, Maaike; Groothuis-Oudshoorn, Catharina G M; IJzerman, Maarten J; van Vlimmeren, Leo A; Boere-Boonekamp, Magda M

    2014-09-01

    Pediatric physical therapy seems to reduce skull deformation in infants with positional preference. However, not all infants show improvement. The study objective was to determine which infant and parent characteristics were related to responses to pediatric physical therapy in infants who were 2 to 4 months old and had positional preference, skull deformation, or both. This was a prospective cohort study. Infants who were 2 to 4 months old and had positional preference, skull deformation, or both were recruited by pediatric physical therapists at the start of pediatric physical therapy. The primary outcome was a good response or a poor response (moderate or severe skull deformation) at 4.5 to 6.5 months of age. Potential predictors for responses to pediatric physical therapy were assessed at baseline with questionnaires, plagiocephalometry, and the Alberta Infant Motor Scale. Univariate and multiple logistic regression analyses with a stepwise backward elimination method were performed. A total of 657 infants participated in the study. At follow-up, 364 infants (55.4%) showed a good response to therapy, and 293 infants (44.6%) showed a poor response. Multiple logistic regression analysis resulted in the identification of several significant predictors for a poor response to pediatric physical therapy at baseline: starting therapy after 3 months of age (adjusted odds ratio [aOR]=1.50, 95% confidence interval [95% CI]=1.04-2.17), skull deformation (plagiocephaly [aOR=2.64, 95% CI=1.67-4.17] or brachycephaly [aOR=3.07, 95% CI=2.09-4.52]), and a low parental satisfaction score (aOR=2.64, 95% CI=1.67-4.17). A low parental satisfaction score indicates low parental satisfaction with the infant's head shape. Information about pediatric physical therapy was collected retrospectively and included general therapy characteristics. Because data were collected retrospectively, no adjustment in therapy for individual participants could be made. Several predictors for responses

  5. Resposta de estruturas lineares sujeitas a carregamento dinâmico Response of linear structures subjected to dynamic loading

    Directory of Open Access Journals (Sweden)

    Vítor Faustino Pereira

    1982-11-01

    Full Text Available Demonstração do emprego da Transformada de Fourier no cálculo da resposta de estruturas de comportamento linear sujeitas a carregamento dinâmico. O emprego desta técnica é vantajoso quando a resposta é obtida numericamente graças ao algoritmo de Transformada Rápida de Fourier. The objective of this work is to show the use of Fourier Transform in the evaluation of the response of linear structures subjected to dynamic loading. The use of this technique is advantageous when the response is obtained numerically due to the Fast Fourier Transform algorithm.

  6. A new locking-free formulation for planar, shear deformable, linear and quadratic beam finite elements based on the absolute nodal coordinate formulation

    Energy Technology Data Exchange (ETDEWEB)

    Nachbagauer, Karin, E-mail: karin.nachbagauer@jku.at; Pechstein, Astrid S., E-mail: astrid.pechstein@jku.at; Irschik, Hans, E-mail: hans.irschik@jku.at [Johannes Kepler University Linz, Institute of Technical Mechanics (Austria); Gerstmayr, Johannes, E-mail: johannes.gerstmayr@lcm.at [Linz Center of Mechatronics GmbH (Austria)

    2011-10-15

    Many widely used beam finite element formulations are based either on Reissner's classical nonlinear rod theory or the absolute nodal coordinate formulation (ANCF). Advantages of the second method have been pointed out by several authors; among the benefits are the constant mass matrix of ANCF elements, the isoparametric approach and the existence of a consistent displacement field along the whole cross section. Consistency of the displacement field allows simpler, alternative formulations for contact problems or inelastic materials. Despite conceptional differences of the two formulations, the two models are unified in the present paper.In many applications, a nonlinear large deformation beam element with bending, axial and shear deformation properties is needed. In the present paper, linear and quadratic ANCF shear deformable beam finite elements are presented. A new locking-free continuum mechanics based formulation is compared to the classical Simo and Vu-Quoc formulation based on Reissner's virtual work of internal forces. Additionally, the introduced linear and quadratic ANCF elements are compared to a fully parameterized ANCF element from the literature. The performance of the respective elements is evaluated through analysis of conventional static and dynamic example problems. The investigation shows that the obtained linear and quadratic ANCF elements are advantageous compared to the original fully parameterized ANCF element.

  7. Simulating Thermal Cycling and Isothermal Deformation Response of Polycrystalline NiTi

    Science.gov (United States)

    Manchiraju, Sivom; Gaydosh, Darrell J.; Noebe, Ronald D.; Anderson, Peter M.

    2011-01-01

    A microstructure-based FEM model that couples crystal plasticity, crystallographic descriptions of the B2-B19' martensitic phase transformation, and anisotropic elasticity is used to simulate thermal cycling and isothermal deformation in polycrystalline NiTi (49.9at% Ni). The model inputs include anisotropic elastic properties, polycrystalline texture, DSC data, and a subset of isothermal deformation and load-biased thermal cycling data. A key experimental trend is captured.namely, the transformation strain during thermal cycling is predicted to reach a peak with increasing bias stress, due to the onset of plasticity at larger bias stress. Plasticity induces internal stress that affects both thermal cycling and isothermal deformation responses. Affected thermal cycling features include hysteretic width, two-way shape memory effect, and evolution of texture with increasing bias stress. Affected isothermal deformation features include increased hardening during loading and retained martensite after unloading. These trends are not captured by microstructural models that lack plasticity, nor are they all captured in a robust manner by phenomenological approaches. Despite this advance in microstructural modeling, quantitative differences exist, such as underprediction of open loop strain during thermal cycling.

  8. Predicting nonlinear properties of metamaterials from the linear response.

    Science.gov (United States)

    O'Brien, Kevin; Suchowski, Haim; Rho, Junsuk; Salandrino, Alessandro; Kante, Boubacar; Yin, Xiaobo; Zhang, Xiang

    2015-04-01

    The discovery of optical second harmonic generation in 1961 started modern nonlinear optics. Soon after, R. C. Miller found empirically that the nonlinear susceptibility could be predicted from the linear susceptibilities. This important relation, known as Miller's Rule, allows a rapid determination of nonlinear susceptibilities from linear properties. In recent years, metamaterials, artificial materials that exhibit intriguing linear optical properties not found in natural materials, have shown novel nonlinear properties such as phase-mismatch-free nonlinear generation, new quasi-phase matching capabilities and large nonlinear susceptibilities. However, the understanding of nonlinear metamaterials is still in its infancy, with no general conclusion on the relationship between linear and nonlinear properties. The key question is then whether one can determine the nonlinear behaviour of these artificial materials from their exotic linear behaviour. Here, we show that the nonlinear oscillator model does not apply in general to nonlinear metamaterials. We show, instead, that it is possible to predict the relative nonlinear susceptibility of large classes of metamaterials using a more comprehensive nonlinear scattering theory, which allows efficient design of metamaterials with strong nonlinearity for important applications such as coherent Raman sensing, entangled photon generation and frequency conversion.

  9. Law of “good and evil”, non-linear function of justice, political regimes and deformation of political systems

    Directory of Open Access Journals (Sweden)

    Sergey Gennadyevich Ol’kov

    2015-06-01

    Full Text Available Objective to clarify the law of good and evil the function rule of justice and to construct mathematical models of political regimes. Methods 1 observation analysis and synthesis 2 deduction and induction 3 using the laws of formal logic 4 formal legal method 5 mathematical modeling 6 the study of mathematical functions 7 differential calculus 8 plotting. Results the author has deduced 1 the nonlinear law function of good and evil 2 the nonlinear function of justice 3 the law function of political regimes. Scientific novelty the author has calculated and found 1 a nonlinear formula DLcol ndashLcol3 which represents the relationship between the acts of legal public relations subjects D and thecollective freedom Lcol ndash the law of quotgood and evilquot 2 a nonlinear formula YD D3 illustrating the relationship between the acts of legal relations subjects D and responsibility for their actions Y ndash a nonlinear function of justice 3 a nonlinear formulanbsp that shows the relationship between the individual Lind and collective freedom Lcol in the negative area of the function definition collective negative freedom and a formulanbsp reflecting the relationship between the individual and collective freedom in the positive area of the function definition collective positive freedom 4 has given a general classification of political regimes in the world describing their functions showing the types of political systems deformation that occur due to the leftwise and rightwise shifts of collective freedom. Practical value the possibility to use the obtained scientific results in the development of various legal theories. nbsp

  10. Non-linear magnetohydrodynamic modeling of plasma response to resonant magnetic perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Orain, F.; Bécoulet, M.; Dif-Pradalier, G.; Nardon, E.; Passeron, C.; Latu, G.; Grandgirard, V.; Fil, A.; Ratnani, A. [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France); Huijsmans, G. [ITER Organization, Route de Vinon, F-13115 Saint-Paul-Lez-Durance (France); Pamela, S. [IIFS-PIIM. Aix Marseille Université - CNRS, 13397 Marseille Cedex20 (France); Chapman, I.; Kirk, A.; Thornton, A. [EURATOM/CCFE Fusion Association, Culham Science Centre, Oxon OX14 3DB (United Kingdom); Hoelzl, M. [Max-Planck-Institut für Plasmaphysik, EURATOM Association, Garching (Germany); Cahyna, P. [Association EURATOM/IPP.CR, Prague (Czech Republic)

    2013-10-15

    The interaction of static Resonant Magnetic Perturbations (RMPs) with the plasma flows is modeled in toroidal geometry, using the non-linear resistive MHD code JOREK, which includes the X-point and the scrape-off-layer. Two-fluid diamagnetic effects, the neoclassical poloidal friction and a source of toroidal rotation are introduced in the model to describe realistic plasma flows. RMP penetration is studied taking self-consistently into account the effects of these flows and the radial electric field evolution. JET-like, MAST, and ITER parameters are used in modeling. For JET-like parameters, three regimes of plasma response are found depending on the plasma resistivity and the diamagnetic rotation: at high resistivity and slow rotation, the islands generated by the RMPs at the edge resonant surfaces rotate in the ion diamagnetic direction and their size oscillates. At faster rotation, the generated islands are static and are more screened by the plasma. An intermediate regime with static islands which slightly oscillate is found at lower resistivity. In ITER simulations, the RMPs generate static islands, which forms an ergodic layer at the very edge (ψ≥0.96) characterized by lobe structures near the X-point and results in a small strike point splitting on the divertor targets. In MAST Double Null Divertor geometry, lobes are also found near the X-point and the 3D-deformation of the density and temperature profiles is observed.

  11. Non-linear magnetohydrodynamic modeling of plasma response to resonant magnetic perturbations

    Science.gov (United States)

    Orain, F.; Bécoulet, M.; Dif-Pradalier, G.; Huijsmans, G.; Pamela, S.; Nardon, E.; Passeron, C.; Latu, G.; Grandgirard, V.; Fil, A.; Ratnani, A.; Chapman, I.; Kirk, A.; Thornton, A.; Hoelzl, M.; Cahyna, P.

    2013-10-01

    The interaction of static Resonant Magnetic Perturbations (RMPs) with the plasma flows is modeled in toroidal geometry, using the non-linear resistive MHD code JOREK, which includes the X-point and the scrape-off-layer. Two-fluid diamagnetic effects, the neoclassical poloidal friction and a source of toroidal rotation are introduced in the model to describe realistic plasma flows. RMP penetration is studied taking self-consistently into account the effects of these flows and the radial electric field evolution. JET-like, MAST, and ITER parameters are used in modeling. For JET-like parameters, three regimes of plasma response are found depending on the plasma resistivity and the diamagnetic rotation: at high resistivity and slow rotation, the islands generated by the RMPs at the edge resonant surfaces rotate in the ion diamagnetic direction and their size oscillates. At faster rotation, the generated islands are static and are more screened by the plasma. An intermediate regime with static islands which slightly oscillate is found at lower resistivity. In ITER simulations, the RMPs generate static islands, which forms an ergodic layer at the very edge (ψ ≥0.96) characterized by lobe structures near the X-point and results in a small strike point splitting on the divertor targets. In MAST Double Null Divertor geometry, lobes are also found near the X-point and the 3D-deformation of the density and temperature profiles is observed.

  12. Review of Response and Damage of Linear and Nonlinear Systems under Multiaxial Vibration

    Directory of Open Access Journals (Sweden)

    Ed Habtour

    2014-01-01

    Full Text Available A review of past and recent developments in multiaxial excitation of linear and nonlinear structures is presented. The objective is to review some of the basic approaches used in the analytical and experimental methods for kinematic and dynamic analysis of flexible mechanical systems, and to identify future directions in this research area. In addition, comparison between uniaxial and multiaxial excitations and their impact on a structure’s life-cycles is provided. The importance of understanding failure mechanisms in complex structures has led to the development of a vast range of theoretical, numerical, and experimental techniques to address complex dynamical effects. Therefore, it is imperative to identify the failure mechanisms of structures through experimental and virtual failure assessment based on correctly identified dynamic loads. For that reason, techniques for mapping the dynamic loads to fatigue were provided. Future research areas in structural dynamics due to multiaxial excitation are identified as (i effect of dynamic couplings, (ii modal interaction, (iii modal identification and experimental methods for flexible structures, and (iv computational models for large deformation in response to multiaxial excitation.

  13. Linear response, multi-order grating interferometry using a reversal shearing imaging system.

    Science.gov (United States)

    Tao, Zhang; Tan, Jiubin; Cui, Jiwen

    2015-10-01

    Linear response, multi-order grating interferometry is proposed to measure grating displacement. The system, a combination of a reversal shearing interferometer and an imaging system, enables calculating multi-order, integrated intensity signals with a linear waveform response. A theoretical multi-order model for the linear response signal analysis is presented with a Fourier series expansion. The results of the experiment, which prove the validity of the theoretical model, indicate a linear response to displacement with a linearity of 98.7% and a resolution of 10 nm. We conclude that the proposed method enables the development of a new class of potent linear response grating interferometry for displacement metrology.

  14. Scaling and linear response in the GOY model

    NARCIS (Netherlands)

    Kadanoff, Leo; Lohse, Detlef; Schörghofer, Norbert

    1997-01-01

    The GOY model is a model for turbulence in which two conserved quantities cascade up and down a linear array of shells. When the viscosity parameter, small nu, Greek, is small the model has a qualitative behavior which is similar to the Kolmogorov theories of turbulence. Here a static solution to th

  15. Response of weeping willows to linear alkylbenzene sulfonate

    DEFF Research Database (Denmark)

    Yu, X.; Trapp, Stefan; Zhou, P.

    2006-01-01

    Linear alkylbenzene sulfonate (LAS) is the most commonly used anionic surfactant in laundry detergents and cleaning agents. LAS compounds are found in surface waters and soils. The short-term acute toxicity of LAS to weeping willows (Salix babylonica L.) was investigated. Willow cuttings were grown...

  16. Stability and response bounds of non-conservative linear systems

    DEFF Research Database (Denmark)

    Pommer, Christian

    2003-01-01

    For a linear system of second order differential equations the stability is studied by Lyapunov's direct method. The Lyapunov matrix equation is solved and a sufficient condition for stability is expressed by the system matrices. For a system which satisfies the condition for stability the Lyapunov...

  17. The linear and non-linear magnetic response of a tri-uranium single molecule magnet

    Science.gov (United States)

    Shivaram, B. S.; Colineau, E.; Griveau, J.; Kumar, P.; Celli, V.

    2017-03-01

    We report here low temperature magnetization isotherms for the single molecule magnet, (UO2-L)3. By analyzing the low temperature magnetization in terms of M  =  χ 1 B  +  χ 3 B 3 we extract the linear susceptibility χ 1 and the leading order nonlinear susceptibility χ 3. We find that χ 1 exhibits a peak at a temperature of T 1  =  10.4 K with χ 3 also exhibiting a peak but at a reduced temperature T 3  =  5 K. At the lowest temperatures the isotherms exhibit a critical field B c  =  11.5 T marked by a clear point of inflection. A minimal Hamiltonian employing S  =  1 (pseudo) spins with only a single energy scale (successfully used to model the behavior of bulk f-electron metamagnets) is shown to provide a good description of the observed linear scaling between T 1, T 3 and B c. We further show that a Heisenberg Hamiltonian previously employed by Carretta et al (2013 J. Phys.: Condens. Matter 25 486001) to model this single molecule magnet gives formulas for the angle averaged susceptibilities (in the Ising limit) very similar to those of the minimal model.

  18. A method of moments for calculating dynamic responses beyond linear response theory

    Institute of Scientific and Technical Information of China (English)

    Kang Yan-Mei; Xu Jian-Xue; Xie Yong

    2005-01-01

    A method of moments for calculating the dynamic response of periodically driven overdamped nonlinear stochastic systems in the general response sense is proposed, which is a modification of the method of moments confined within linear response theory. The calculating experience suggests that the proposed technique is simple and efficient in implementation, and the comparison with stochastic simulation shows that the first three orders of susceptibilities calculated by the proposed technique have high accuracy. The dependence of the spectral amplification parameters at the first three harmonics on the noise intensity is also investigated, and another observed phenomenon of stochastic resonance in the systems induced by the location of a single periodic orbit is disclosed and explained.

  19. Measurements of dynamical response of non-linear systems. How hard can it be?

    DEFF Research Database (Denmark)

    Darula, Radoslav

    2015-01-01

    Measurements of a dynamical response of linear system are widely used in praxis, they are standardized and well known. On the other hand, for the non-linear systems the principle of superposition can’t be applied and also the non-linear systems can excite the harmonics or undergo jump phenomena...

  20. CFORM- LINEAR CONTROL SYSTEM DESIGN AND ANALYSIS: CLOSED FORM SOLUTION AND TRANSIENT RESPONSE OF THE LINEAR DIFFERENTIAL EQUATION

    Science.gov (United States)

    Jamison, J. W.

    1994-01-01

    CFORM was developed by the Kennedy Space Center Robotics Lab to assist in linear control system design and analysis using closed form and transient response mechanisms. The program computes the closed form solution and transient response of a linear (constant coefficient) differential equation. CFORM allows a choice of three input functions: the Unit Step (a unit change in displacement); the Ramp function (step velocity); and the Parabolic function (step acceleration). It is only accurate in cases where the differential equation has distinct roots, and does not handle the case for roots at the origin (s=0). Initial conditions must be zero. Differential equations may be input to CFORM in two forms - polynomial and product of factors. In some linear control analyses, it may be more appropriate to use a related program, Linear Control System Design and Analysis (KSC-11376), which uses root locus and frequency response methods. CFORM was written in VAX FORTRAN for a VAX 11/780 under VAX VMS 4.7. It has a central memory requirement of 30K. CFORM was developed in 1987.

  1. On the response of Escherichia coli to high rates of deformation

    Science.gov (United States)

    Fitzmaurice, B. C.; Painter, J. D.; Appleby-Thomas, G. J.; Wood, D. C.; Hazael, R.; McMillan, P. F.

    2017-01-01

    While a large body of work exists on the low strain-rate loading of biological systems such as bacteria, there is a paucity of information on the response of such organisms at high rates of deformation. Here, the response of a readily accessible strain of bacteria, Escherichia coli (E. coli), has been examined under shock loading conditions. Although previous studies have shown greatly reduced growth in shock conditions up to several GPa, relationships between loading conditions and bacterial response have yet to be fully elucidated. Initial results of a more rigorous investigation into the 1D shock loading response of E. coli are presented here, expectantly leading to a more comprehensive view of its behaviour when exposed to high pressures. Comparison has been drawn to provide insight into the importance of the nature of the loading regime to the survival of these biological systems.

  2. Linear response of galactic halos to adiabatic gravitational perturbations

    CERN Document Server

    Murali, C; Murali, Chigurupati; Tremaine, Scott

    1997-01-01

    We determine the response of a self-similar isothermal stellar system to small adiabatic gravitational perturbations. For odd spherical harmonics, the response is identical to the response of the analogous isothermal fluid system. For even spherical harmonics, the response can be regarded as an infinite series of wavetrains in $\\log r$, implying alternating compression and rarefaction in equal logarithmic radius intervals. Partly because of the oscillatory nature of the solutions, tidal fields from external sources are not strongly amplified by an intervening isothermal stellar system, except at radii can even screen the external tidal field in a manner analogous to Debye screening. As Weinberg has pointed out, individual resonances in a stellar system can strongly amplify external tidal fields over a limited radial range, but we cannot address this possibility because we examine only adiabatic perturbations. We also discuss the application of our method to the halo response caused by the slow growth of an em...

  3. Using crosscorrelation techniques to determine the impulse response of linear systems

    Science.gov (United States)

    Dallabetta, Michael J.; Li, Harry W.; Demuth, Howard B.

    1993-01-01

    A crosscorrelation method of measuring the impulse response of linear systems is presented. The technique, implementation, and limitations of this method are discussed. A simple system is designed and built using discrete components and the impulse response of a linear circuit is measured. Theoretical and software simulation results are presented.

  4. A quantum-mechanical perspective on linear response theory within polarizable embedding

    DEFF Research Database (Denmark)

    List, Nanna Holmgaard; Norman, Patrick; Kongsted, Jacob

    2017-01-01

    We present a derivation of linear response theory within polarizable embedding starting from a rigorous quantum-mechanical treatment of a composite system. To this aim, two different subsystem decompositions (symmetric and nonsymmetric) of the linear response function are introduced and the pole...

  5. Linear response of a pre- and post-selected system to an external field

    Energy Technology Data Exchange (ETDEWEB)

    Ban, Masashi, E-mail: ban.masashi@ocha.ac.jp

    2015-02-06

    Linear response to an external field is studied for a quantum system with pre- and post-selection. Effects of an external field on strong and weak values of a system observable are found. The external field applied after the measurement of the observable influences the linear response of the system through post-selection. A time-symmetric property in the linear response is found. - Highlights: • The linear response theory is applied to a quantum system with pre-selection and post-selection. • It is found how an external field affects strong and weak values of a measured system observable • Not only an external field before measurement but also one after measurement influences the linear response due to the post-selection.

  6. Response of weeping willows to linear alkylbenzene sulfonate.

    Science.gov (United States)

    Yu, Xiaozhang; Trapp, Stefan; Zhou, Puhua; Peng, Xiaoying; Cao, Xi

    2006-06-01

    Linear alkylbenzene sulfonate (LAS) is the most commonly used anionic surfactant in laundry detergents and cleaning agents. LAS compounds are found in surface waters and soils. The short-term acute toxicity of LAS to weeping willows (Salix babylonica L.) was investigated. Willow cuttings were grown in hydroponic solution spiked with LAS at 24.0+/-1 degrees C for 192 h. The normalized relative transpiration of plants was used to determine toxicity. Severe reduction of the transpiration was only found for high doses of LAS (240 mgl(-1)). Chlorophyll contents in leaves of treated plants varied with the dose of LAS, but there was no significant linear correlation. The activities of the enzymes superoxide dismutases (SOD), catalase (CAT), and peroxidase (POD) were quantified at the end of experiments. At higher concentrations of LAS (240 mgl(-1)), the activities of SOD and CAT were decreased. The correlation between the dose of LAS and the POD activity in leaf cells was the highest of all enzyme assays (R(2)=0.5). EC(50) values for a 50% inhibition of the transpiration of the trees were estimated to 374 mgl(-1) (72 h) and 166 mgl(-1) (192 h). Results from this experiment indicated that phytotoxic effects of LAS on willow trees are not expected for normal environmental conditions.

  7. Modification of ovalbumin with fructooligosaccharides: consequences for network morphology and mechanical deformation responses.

    Science.gov (United States)

    Munialo, Claire D; Ortega, Rodrigo G; van der Linden, Erik; de Jongh, Harmen H J

    2014-11-25

    The Maillardation of proteins has been used as a natural alternative to improve its functionality by covalent coupling of proteins with saccharides. However, the impact of Maillard reaction on the structural aspects of protein networks and, as a consequence, the mechanical breakdown properties of the gel networks has not been reported. The objective of this study was to evaluate how the attachment of linear oligo-sugar moieties onto ovalbumin affects its aggregation, network morphology, and consequently the mechanical deformation properties including the ability of the networks to elastically store energy in this material. To potentially alter the morphology of the network structure, ovalbumin was modified by conjugating some of its amino groups with fructooligosaccharide (FOS) moieties via the Maillard reaction. It was demonstrated that the attachment of FOS to ovalbumin does not affect the integrity of the secondary and tertiary structure as characterized using circular dichroism and tryptophan fluorescence. Differences in the network morphology were observed by scanning electron microscopy for FOS-modified ovalbumin variants. Upon increased modification, the microstructure of the gels had more and larger pores and had thinner strands than nonmodified variants. Evaluation of the large deformation properties of the gels demonstrated that FOS-modified gels were less strong and less brittle and showed lower stiffness than nonmodified variants. The recoverable energy (elastically stored energy) of gels reduced with an increase in the degree of modification. The results show that the attachment of FOS to ovalbumin alters the structural and mechanical (large) breakdown properties of the protein gels. The consequences of the alteration of the network structure and large deformation properties of FOS-modified ovalbumin offer opportunities to efficiently design food materials with desirable techno-functional applications.

  8. SU-E-J-148: Evaluating Tumor Response with a Commercially Available Deformable Registration System

    Energy Technology Data Exchange (ETDEWEB)

    Bowling, J; Ramsey, C [Thompson Cancer Survival Center, Knoxville, TN (United States)

    2014-06-01

    Purpose: The purpose of this study is to present a method for evaluating the response to treatment using a commercially available deformable image registration software package (Velocity Medical Systems) and repeat PET/CT imaging. This technique can be used to identify volumes that are risk for tumor recurrence. Methods: Response to treatment was evaluated using PET/CT images acquired prior-to and post-treatment for radiation therapy patients treated with concurrent chemotherapy. Velocity (Version 3.0.1) was used to deform the initial PET/CT to the post treatment PET/CT. The post-treatment PET images were then subtracted from the pre-treatment PET images. The resulting re-sampled image is a three-dimensional SUV difference map that shows pixels with increasing SUV values. SUV values increases greater than 2.5 in the post treatment images were identified for additional follow-up. Results: A total of 5 Lung patients were analyzed as part of this study. One lung patient in the cohort had an SUV increase of +3.28 that was identified using the SUV difference map. This volume of increased uptake was located outside the treatment field and adjacent to the 35 Gy isodose line. The remaining four patients all had SUV decreases inside the planning target volume, and no unexpected areas of increase outside the irradiated volumes. All five patients were analyzed using standard tools inside the Velocity application. Conclusion: The response to treatment can easily be measured using serial PET/CT images and a commercially available deformable image registration. This provides both the radiation oncologists and medical oncologists with a quantitative assessment of their treatment to use in patient follow-up.

  9. An Alternative Three-Term Decomposition for Single Crystal Deformation Motivated by Non-Linear Elastic Dislocation Solutions

    Science.gov (United States)

    2014-04-01

    irreversible deformation, the three-term model allows for residual elastic strains— including dilatation observed in experiments and atomic simulations...residual elastic strains—including dilatation observed in experiments and atomic simulations—not addressed by conventional two-term crystal plasticity...gradient for an element of crystalline material. For simplicity, thermal effects are omitted, gliding dislocations are the only kind of defect considered

  10. Stability and response bounds of non-conservative linear systems

    DEFF Research Database (Denmark)

    Kliem, Wolfhard; Pommer, Christian

    2004-01-01

    This paper develops a stability theorem and response bounds for non-conservative systems of the form MX + (D + G)x + (K + N)x = f(t), with hermitian positive-definite matrices M, D and K, and skew-hermitian matrices G and N. To this end, we first find a Lyapunov function by solving the Lyapunov...... matrix equation. Then, if a system satisfies the condition of the stability theorem, the associated Lyapunov function can be used to obtain response bounds for the norms as well as for the individual coordinates of the solution. Examples from rotor dynamics illustrate the results....

  11. Hydrodynamic of a deformed bubble in linear shear flow; Hydrodynamique d'une bulle deformee dans un ecoulement cisaille

    Energy Technology Data Exchange (ETDEWEB)

    Adoua, S.R

    2007-07-15

    This work is devoted to the study of an oblate spheroidal bubble of prescribed shape set fixed in a linear shear flow using direct numerical simulation. The three dimensional Navier-Stokes equations are solved in orthogonal curvilinear coordinates using a finite volume method. The bubble response is studied over a wide range of the aspect ratio (1-2.7), the bubble Reynolds number (50-2000) and the non-dimensional shear rate (0.-1.2). The numerical simulations shows that the shear flow imposes a plane symmetry of the wake whatever the parameters of the flow. The trailing vorticity is organized into two anti-symmetrical counter rotating tubes with a sign imposed by the competition of two mechanisms (the Lighthill mechanism and the instability of the wake). Whatever the Reynolds number, the lift coefficient reaches the analytical value obtained in an inviscid, weakly sheared flow corresponding to a lift force oriented in the same direction as that of a spherical bubble. For moderate Reynolds numbers, the direction of the lift force reverses when the bubble aspect ratio is large enough as observed in experiments. This reversal occurs for aspect ratios larger than 2.225 and is found to be directly linked to the sign of the trailing vorticity which is concentrated within two counter-rotating threads which propel the bubble in a direction depending of their sign of rotation. The behavior of the drag does not revel any significant effect induced by the wake structure and follows a quadratic increase with the shear rate. Finally, the torque experienced by the bubble also reverses for the same conditions inducing the reversal of the lift force. By varying the orientation of the bubble in the shear flow, a stable equilibrium position is found corresponding to a weak angle between the small axis of the bubble and the flow direction. (author)

  12. Linear elastic response of tubes to internal detonation loading

    NARCIS (Netherlands)

    Beltman, W.M.; Shepherd, J.E.

    2002-01-01

    This paper deals with the structural response of a tube to an internal gaseous detonation. An internal detonation produces a pressure load that propagates down the tube. Because the speed of the gaseous detonation can be comparable to the flexural wave group speed, excitation of flexural waves in th

  13. The hydrodynamical response of a tilted circumbinary disc linear theory and non-linear numerical simulations

    CERN Document Server

    Larwood, J D; Larwood, John D.; Papaloizou, John C.B.

    1996-01-01

    In this paper we present an analytical and numerical study of the response of a circumbinary disc subject to the tidal-forcing of a binary with a fixed circular orbit. We consider fluid discs with a range of thicknesses and binaries with a range of mass ratios, orbital separations and inclination angles. Our numerical simulations are implemented using a SPH code. For our unperturbed disc models, we write a scaling relation for the shear viscosity and deduce that the disc thickness cannot be varied without affecting the viscosity in these kinds of SPH disc models. It is found that maintainance of an inner cavity owing to the tidal truncation of the disc is effective for non-zero orbital inclinations. Also we show that our model discs may precess approximately like rigid bodies, provided that the disc is able to communicate on a length scale comparable to the inner boundary radius by either sonic or viscous effects, in a sufficiently small fraction of the local precession period. Furthermore, the disc precessio...

  14. Efficient Algorithms for Estimating the Absorption Spectrum within Linear Response TDDFT

    Energy Technology Data Exchange (ETDEWEB)

    Brabec, Jiri; Lin, Lin; Shao, Meiyue; Govind, Niranjan; Yang, Chao; Saad, Yousef; Ng, Esmond

    2015-10-06

    We present two iterative algorithms for approximating the absorption spectrum of molecules within linear response of time-dependent density functional theory (TDDFT) framework. These methods do not attempt to compute eigenvalues or eigenvectors of the linear response matrix. They are designed to approximate the absorption spectrum as a function directly. They take advantage of the special structure of the linear response matrix. Neither method requires the linear response matrix to be constructed explicitly. They only require a procedure that performs the multiplication of the linear response matrix with a vector. These methods can also be easily modified to efficiently estimate the density of states (DOS) of the linear response matrix without computing the eigenvalues of this matrix. We show by computational experiments that the methods proposed in this paper can be much more efficient than methods that are based on the exact diagonalization of the linear response matrix. We show that they can also be more efficient than real-time TDDFT simulations. We compare the pros and cons of these methods in terms of their accuracy as well as their computational and storage cost.

  15. Linear response of homogeneous nuclear matter with energy density functionals

    Energy Technology Data Exchange (ETDEWEB)

    Pastore, A. [Institut d’Astronomie et d’Astrophysique, CP 226, Université Libre de Bruxelles, B-1050 Bruxelles (Belgium); Davesne, D., E-mail: davesne@ipnl.in2p3.fr [Institut de Physique Nucléaire de Lyon, CNRS-IN2P3, UMR 5822, Université Lyon 1, F-69622 Villeurbanne (France); Navarro, J. [IFIC (CSIC University of Valencia), Apdo. Postal 22085, E-46071 Valencia (Spain)

    2015-03-01

    Response functions of infinite nuclear matter with arbitrary isospin asymmetry are studied in the framework of the random phase approximation. The residual interaction is derived from a general nuclear Skyrme energy density functional. Besides the usual central, spin–orbit and tensor terms it could also include other components as new density-dependent terms or three-body terms. Algebraic expressions for the response functions are obtained from the Bethe–Salpeter equation for the particle–hole propagator. Applications to symmetric nuclear matter, pure neutron matter and asymmetric nuclear matter are presented and discussed. Spin–isospin strength functions are analyzed for varying conditions of density, momentum transfer, isospin asymmetry, and temperature for some representative Skyrme functionals. Particular attention is paid to the discussion of instabilities, either real or unphysical, which could manifest in finite nuclei.

  16. Item Response Theory Using Hierarchical Generalized Linear Models

    Directory of Open Access Journals (Sweden)

    Hamdollah Ravand

    2015-03-01

    Full Text Available Multilevel models (MLMs are flexible in that they can be employed to obtain item and person parameters, test for differential item functioning (DIF and capture both local item and person dependence. Papers on the MLM analysis of item response data have focused mostly on theoretical issues where applications have been add-ons to simulation studies with a methodological focus. Although the methodological direction was necessary as a first step to show how MLMs can be utilized and extended to model item response data, the emphasis needs to be shifted towards providing evidence on how applications of MLMs in educational testing can provide the benefits that have been promised. The present study uses foreign language reading comprehension data to illustrate application of hierarchical generalized models to estimate person and item parameters, differential item functioning (DIF, and local person dependence in a three-level model.

  17. Effect of Actin Filament on Deformation-Induced Ca2+ Response in Osteoblast-Like Cells

    Science.gov (United States)

    Adachi, Taiji; Murai, Takayuki; Hoshiai, Sodai; Tomita, Yoshihiro

    Under the influence of mechanical environment, bone structure is formed and maintained by adaptive remodeling that involves osteoclastic resorption and osteoblastic formation. In the mechanotransduction system in osteoblasts, it is believed that intracellular calcium plays a fundamental role and cytoskeletal actin filament is a crucial component for the signal transduction process. To clarify the role of actin filament in deformation-induced Ca2+ signaling, osteoblast-like cells (MC3T3-E1) with different actin filament densities controlled by cytochalasin D were subjected to tensile strain in vitro. The change in intracellular Ca2+ concentration labeled by fluo-3 was observed using a confocal laser-scanning microscope. As a result, the disruption of the actin filament was found to significantly suppress the deformation-induced Ca2+ response that was regulated according to the degree of actin filament organization. This result indicates that the actin filament is indispensable for the quantitative regulation of Ca2+ signaling in response to a mechanical stimulus in osteoblasts.

  18. Modeling and non-linear responses of MEMS capacitive accelerometer

    Directory of Open Access Journals (Sweden)

    Sri Harsha C.

    2014-01-01

    Full Text Available A theoretical investigation of an electrically actuated beam has been illustrated when the electrostatic-ally actuated micro-cantilever beam is separated from the electrode by a moderately large gap for two distinct types of geometric configurations of MEMS accelerometer. Higher order nonlinear terms have been taken into account for studying the pull in voltage analysis. A nonlinear model of gas film squeezing damping, another source of nonlinearity in MEMS devices is included in obtaining the dynamic responses. Moreover, in the present work, the possible source of nonlinearities while formulating the mathematical model of a MEMS accelerometer and their influences on the dynamic responses have been investigated. The theoretical results obtained by using MATLAB has been verified with the results obtained in FE software and has been found in good agreement. Criterion towards stable micro size accelerometer for each configuration has been investigated. This investigation clearly provides an understanding of nonlinear static and dynamics characteristics of electrostatically micro cantilever based device in MEMS.

  19. [Modeling and simulation of responses from ultrasonic linear phased array].

    Science.gov (United States)

    He, Wenjing; Zhu, Yuanzhong; Wang, Yufeng; He, Lingli; Lai, Siyu

    2012-10-01

    Phased array transducers are very attractive because the beam generated by the arrays can be electronically focused and steered. The present work characterizes far-field 2D properties of phased array system by functions that are deduced from rectangle source, rectangle line array and phased array based on point source. Results are presented for the distribution of ultrasound intensity on plane xoz and on x-axis by simulation using numerical calculation. It is shown that the shape of response of rectangle line array is modulated by the single array element. It is also demonstrated that the delay time of phased array is the key to steer the beam, sacrificing the value of main lobe and increasing the number of side lobes.

  20. Linear Ordinary Differential Equations with Constant Coefficients. Revisiting the Impulsive Response Method Using Factorization

    Science.gov (United States)

    Camporesi, Roberto

    2011-01-01

    We present an approach to the impulsive response method for solving linear constant-coefficient ordinary differential equations based on the factorization of the differential operator. The approach is elementary, we only assume a basic knowledge of calculus and linear algebra. In particular, we avoid the use of distribution theory, as well as of…

  1. Non-Linear Wave Loads and Ship responses by a time-domain Strip Theory

    DEFF Research Database (Denmark)

    Xia, Jinzhu; Wang, Zhaohui; Jensen, Jørgen Juncher

    1998-01-01

    A non-linear time-domain strip theory for vertical wave loads and ship responses is presented. The theory is generalized from a rigorous linear time-domain strip theory representaton. The hydrodynamic memory effect due to the free surface is approximated by a higher order differential equation...

  2. Linear Ordinary Differential Equations with Constant Coefficients. Revisiting the Impulsive Response Method Using Factorization

    Science.gov (United States)

    Camporesi, Roberto

    2011-01-01

    We present an approach to the impulsive response method for solving linear constant-coefficient ordinary differential equations based on the factorization of the differential operator. The approach is elementary, we only assume a basic knowledge of calculus and linear algebra. In particular, we avoid the use of distribution theory, as well as of…

  3. RETRACTED: The Nonlinear Compressive Response and Deformation of an Auxetic Cellular Structure under In-Plane Loading

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    2015-01-01

    Full Text Available At the request of the Author, the following article Zhang, W, Hou, W, Hu, Ping and Ma, Z (2014 The Nonlinear Compressive Response and Deformation of an Auxetic Cellular Structure under In-Plane Loading Advances in Mechanical Engineering published 17 November 2014. doi: 10.1155/2014/214681has been retracted due to errors discovered by the authors. On Page 3, the definition of component force in Equation 4 is incorrect. (2 On Page 4, the definition of component force in Equation 11 is incorrect. Moreover this equation should not have parameterM(length of cell wall, because a mistake was made in the process of calculation. Because of the above reasons, the conclusion obtained from the mechanical model is incorrect and should instead state that the Elastic Buckling and Plastic Collapse are both yield modes of this structure (3 On Page 5, the FEA model used in this article is not appropriate, because the deformation of single cell is not homogeneous, which means that the geometrical non-linear effect on single cell model is greater. So in the actual whole structure we may not obtain the results that were described in Page 6 Paragraph 2. (4 The data in figures 8 (page 6 and 9 (page 7 is incorrect and the values of effective Young’s modulus and plateau stress are much larger than reasonable values. The definition of effective stress is wrong in the FEA model, which means the effective stress should be calculated by the total width of cell instead of length of horizontal cell wall. For example, in Figure 8, the plateau stress can reach 140Mpa, this is not reasonable because there are many holes in this cellular structure, and its mechanical properties should be much lower than material properties of cell wall. The reasonable plateau stress should be around 2Mpa. The authors takes responsibility for these errors and regret the publication of invalid results. The nonlinear compressive response and deformation of an auxetic cellular structure that has

  4. An implicit three-dimensional model for describing the inelastic response of solids undergoing finite deformation

    Science.gov (United States)

    Rajagopal, K. R.; Srinivasa, A. R.

    2016-08-01

    The aim of this paper is to develop a new unified class of 3D nonlinear anisotropic finite deformation inelasticity model that (1) exhibits rate-independent or dependent hysteretic response (i.e., response wherein reversal of the external stimuli does not cause reversal of the path in state space) with or without yield surfaces. The hysteresis persists with quasistatic loading. (2) Encompasses a wide range of different types of inelasticity models (such as Mullins effect in rubber, rock and soil mechanics, traditional metal plasticity, hysteretic behavior of shape memory materials) into a simple unified framework that is relatively easy to implement in computational schemes and (3) does not require any a priori particular notion of plastic strain or yield function. The core idea behind the approach is the development of an system of implicit rate equations that allow for the continuity of the response but with different rates along different directions. The theory, which is in purely mechanical setting, subsumes and generalizes many commonly used approaches for hypoelasticity and rate-independent plasticity. We illustrate its capability by modeling the Mullins effect which is the inelastic behavior of certain rubbery materials. We are able to simulate the entire cyclic response without the use of additional internal variables, i.e., the entire response is modeled by using an implicit function of stress and strain measures and their rates.

  5. Annealing response of binary Al–7Mg alloy deformed by equal channel angular pressing

    Energy Technology Data Exchange (ETDEWEB)

    Zha, Min, E-mail: min.zha@material.ntnu.no [Department of Materials Science and Engineering, Norwegian University of Science and Technology, 7491 Trondheim (Norway); Li, Yanjun [SINTEF Materials and Chemistry, 7465 Trondheim (Norway); Mathiesen, Ragnvald H.; Bjørge, Ruben [Department of Physics, Norwegian University of Science and Technology, 7491 Trondheim (Norway); Roven, Hans J. [Department of Materials Science and Engineering, Norwegian University of Science and Technology, 7491 Trondheim (Norway)

    2013-12-01

    The annealing response in a binary Al–7Mg alloy processed at room temperature by equal channel angular pressing (ECAP) has been investigated via X-ray diffraction (XRD), electron-probe micro analysis (EPMA) and electron backscattering diffraction (EBSD). After ECAP and subsequent annealing, Mg remains mainly homogeneously distributed in solid solution. A bimodal structure with ultrafine grains accompanied by micrometer-sized crystallites was developed after 3 passes. Upon annealing at ∼275 °C for 96 h, extensive recovery was observed in the as-deformed material, leading to a relatively uniform microstructure; at ∼300 °C a discontinuous recrystallization initiated in less than 30 s with subsequent grain growth clearly evident. Such remarkable thermal stability, i.e., slower recovery and recrystallization kinetics, of the present material, in contrast to other severely deformed commercial pure Al and Al–Mg alloys, is due mainly to the presence of high Mg solid solution contents, the formation of the bimodal structure consisting of both coarse crystallites and ultrafine grains. In addition, the possible Mg-containing precipitates during annealing might also retard the recrystallization kinetics.

  6. Deformation and Stress Response of Carbon Nanotubes/UHMWPE Composites under Extensional-Shear Coupling Flow

    Science.gov (United States)

    Wang, Junxia; Cao, Changlin; Yu, Dingshan; Chen, Xudong

    2017-05-01

    In this paper, the effect of varying extensional-shear couple loading on deformation and stress response of Carbon Nanotubes/ ultra-high molecular weight polyethylene (CNTs/UHMWPE) composites was investigated using finite element numerical simulation, with expect to improve the manufacturing process of UHMWPE-based composites with reduced stress and lower distortion. When applying pure extensional loading and pure X-Y shear loading, it was found that the risk of a structural breakage greatly rises. For identifying the coupling between extensional and shear loading, distinct generations of force loading were defined by adjusting the magnitude of extensional loading and X-Y shear loading. It was shown that with the decrement of X-Y shear loading the deformation decreases obviously where the maximal Mises stress in Z-direction at 0.45 m distance is in the range from 24 to 10 MPa and the maximal shear stress at 0.61 m distance is within the range from 0.9 to 0.3 MPa. In addition, all the stresses determined were clearly below the yield strength of CNTs/UHMWPE composites under extensional-shear couple loading.

  7. Linear ordinary differential equations with constant coefficients. Revisiting the impulsive response method using factorization

    Science.gov (United States)

    Camporesi, Roberto

    2011-06-01

    We present an approach to the impulsive response method for solving linear constant-coefficient ordinary differential equations based on the factorization of the differential operator. The approach is elementary, we only assume a basic knowledge of calculus and linear algebra. In particular, we avoid the use of distribution theory, as well as of the other more advanced approaches: Laplace transform, linear systems, the general theory of linear equations with variable coefficients and the variation of constants method. The approach presented here can be used in a first course on differential equations for science and engineering majors.

  8. Prediction of Nociceptive Responses during Sedation by Linear and Non-Linear Measures of EEG Signals in High Frequencies.

    Directory of Open Access Journals (Sweden)

    Umberto Melia

    Full Text Available The level of sedation in patients undergoing medical procedures evolves continuously, affected by the interaction between the effect of the anesthetic and analgesic agents and the pain stimuli. The monitors of depth of anesthesia, based on the analysis of the electroencephalogram (EEG, have been progressively introduced into the daily practice to provide additional information about the state of the patient. However, the quantification of analgesia still remains an open problem. The purpose of this work is to improve the prediction of nociceptive responses with linear and non-linear measures calculated from EEG signal filtered in frequency bands higher than the traditional bands. Power spectral density and auto-mutual information function was applied in order to predict the presence or absence of the nociceptive responses to different stimuli during sedation in endoscopy procedure. The proposed measures exhibit better performances than the bispectral index (BIS. Values of prediction probability of Pk above 0.75 and percentages of sensitivity and specificity above 70% were achieved combining EEG measures from the traditional frequency bands and higher frequency bands.

  9. Numerical Simulation of Seabed Response and Liquefaction due to Non-linear Waves

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jin-feng; ZHANG Qing-he; HAN Tao; QIN Chong-ren

    2005-01-01

    Based on Biot's consolidation theory, a two-dimensional model for computation of the seabed response to waves is presented with the finite element method. Numerical results for different wave conditions are obtained, and the effects of wave non-linearity on the wave-induced seabed response are examined. Moreover, the wave-induced momentary liquefaction in uniform and inhomogeneous seabeds is investigated. It is shown that the wave non-linearity affects the distribution of the wave-induced pore pressure and effective stresses, while the influence of wave non-linearity on the seabed liquefaction potential is not so significant.

  10. Experimental Investigation of Dynamic Response and Deformation of Aluminium Honeycomb Sandwich Panels Subjected to Underwater Impulsive Loads

    Directory of Open Access Journals (Sweden)

    Da-Lin Xiang

    2015-01-01

    Full Text Available The response of aluminium sandwich panels with three thicknesses’ core subjected to different underwater loading levels has been studied in the fluid-structure interaction (FSI experiments. The transient response of the panels is measured using a three-dimensional (3D Digital Image Correlation (DIC system, along with high-speed photography. The full-field shape and displacement profiles of dry face sheets were recorded in real time compared with those of monolithic plate. The out-of-plane deflection and in-plane strain were quantified and analyzed. Three typical deformation modes of sandwich panel were identified. The results show that the core structure is crushed resulting in an initial large circular shape of deformation in the center area of panels. From this moment on, the panel is starting to act as a free vibration beam with initial velocities. The deformation modes consisted of homogeneous large deformation for both face sheets, obvious deformation border on wet face sheet, core node imprinting, remarkable wrinkled skin of deformation border, and a partial delamination and partial tear failure of the dry face. The blast-resistance of sandwich panel can be highly efficiently improved by increasing the thickness of core structure.

  11. Effect of plastic deformation on the acoustoelastic response of some materials

    Science.gov (United States)

    Daami, T.; Touratier, M.; Castex, L.

    1987-12-01

    Acoustoelastic birefringence is measured with the acoustic polarimeter by transmitting ultrasonic shear waves at two perpendicular polarizations through the thickness of several uniaxial test specimens. The results are available for the following materials: SAE 1010 and SAE 4118 steel, pure titanium, 2024 aluminum and 60-40 brass, but are only presented here for SAE 4118 steel and pure titanium. The uniaxial test specimens have been subjected to plastic deformation followed by complete unloading. It is shown that the assumption that the plastic flow leading to the residual-stress state does not change the acoustic response of the material, does not hold for all materials and that further characterization development is required for general quantitative residual-stress determination.

  12. Linearized theory of peridynamic states.

    Energy Technology Data Exchange (ETDEWEB)

    Silling, Stewart Andrew

    2009-04-01

    A state-based peridynamic material model describes internal forces acting on a point in terms of the collective deformation of all the material within a neighborhood of the point. In this paper, the response of a state-based peridynamic material is investigated for a small deformation superposed on a large deformation. The appropriate notion of a small deformation restricts the relative displacement between points, but it does not involve the deformation gradient (which would be undefined on a crack). The material properties that govern the linearized material response are expressed in terms of a new quantity called the modulus state. This determines the force in each bond resulting from an incremental deformation of itself or of other bonds. Conditions are derived for a linearized material model to be elastic, objective, and to satisfy balance of angular momentum. If the material is elastic, then the modulus state is obtainable from the second Frechet derivative of the strain energy density function. The equation of equilibrium with a linearized material model is a linear Fredholm integral equation of the second kind. An analogue of Poincare's theorem is proved that applies to the infinite dimensional space of all peridynamic vector states, providing a condition similar to irrotationality in vector calculus.

  13. Linearized theory of peridynamic states.

    Energy Technology Data Exchange (ETDEWEB)

    Silling, Stewart Andrew

    2009-04-01

    A state-based peridynamic material model describes internal forces acting on a point in terms of the collective deformation of all the material within a neighborhood of the point. In this paper, the response of a state-based peridynamic material is investigated for a small deformation superposed on a large deformation. The appropriate notion of a small deformation restricts the relative displacement between points, but it does not involve the deformation gradient (which would be undefined on a crack). The material properties that govern the linearized material response are expressed in terms of a new quantity called the modulus state. This determines the force in each bond resulting from an incremental deformation of itself or of other bonds. Conditions are derived for a linearized material model to be elastic, objective, and to satisfy balance of angular momentum. If the material is elastic, then the modulus state is obtainable from the second Frechet derivative of the strain energy density function. The equation of equilibrium with a linearized material model is a linear Fredholm integral equation of the second kind. An analogue of Poincare's theorem is proved that applies to the infinite dimensional space of all peridynamic vector states, providing a condition similar to irrotationality in vector calculus.

  14. Response of a fluid-immersed microcantilever close to a deformable body

    Energy Technology Data Exchange (ETDEWEB)

    Clarke, R. J.; Lee, T. C.; Cater, J. E. [Department of Engineering Science, University of Auckland, Auckland (New Zealand); Bachtiar, V. [Department of Mechanical Engineering, University of Melbourne, Parkville (Australia); Minton, J. [Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge (United Kingdom)

    2015-03-07

    The importance of hydrodynamics upon the response of a microcantilever immersed in a viscous fluid has been well established [J. E. Sader, J. Appl. Phys. 84, 64 (1998); C. A. Eysden and J. E. Sader, J. Appl. Phys. 101, 044908 (2007)]. It has previously been shown that the presence of a nearby rigid planar surface can significantly alter a microcantilever's non-contact response, through microcantilever–surface hydrodynamic interactions [C. P. Green and J. E. Sader, Phys. Fluids 17, 073102 (2005); C. P. Green and J. E. Sader, J. Appl. Phys. 98, 114913 (2005); R. J. Clarke et al., J. Fluid Mech. 545, 397426 (2005); R. J. Clarke et al., Phys. Rev. Lett. 96, 050801 (2006).]. In cases where the nearby surface is a finite-sized deformable body, such as in noncontact microrheology measurements, we expect to see further changes in the microcantilever's response. Hence, we here compute the thermal spectra of several microcantilevers in the presence of different compliant samples that have the characteristics of soft biological fibres. Our findings demonstrate that the elastohydrodynamic regime can substantially dictate the extent to which the compliance of a given body is evident in the microcantilever's thermal spectra, and suggest that certain nondimensional quantities should lie within particular, ranges for this to be the case. We expect these findings to be of interest in areas such as Atomic Force Microscopy, microsensing, and non-contact microrheology.

  15. Recent results on stability and response bounds of linear systems - a review

    DEFF Research Database (Denmark)

    Pommer, Christian; Kliem, Wolfhard

    2006-01-01

    of stability and response bounds of linear systems. In addition to reporting some interesting recent stability investigations, the basic concepts of stability are reviewed, and a short introduction to Lyapunov’s direct method is also presented. Particularly important for applications are response bounds...

  16. A review of linear response theory for general differentiable dynamical systems

    Science.gov (United States)

    Ruelle, David

    2009-04-01

    The classical theory of linear response applies to statistical mechanics close to equilibrium. Away from equilibrium, one may describe the microscopic time evolution by a general differentiable dynamical system, identify nonequilibrium steady states (NESS) and study how these vary under perturbations of the dynamics. Remarkably, it turns out that for uniformly hyperbolic dynamical systems (those satisfying the 'chaotic hypothesis'), the linear response away from equilibrium is very similar to the linear response close to equilibrium: the Kramers-Kronig dispersion relations hold, and the fluctuation-dispersion theorem survives in a modified form (which takes into account the oscillations around the 'attractor' corresponding to the NESS). If the chaotic hypothesis does not hold, two new phenomena may arise. The first is a violation of linear response in the sense that the NESS does not depend differentiably on parameters (but this nondifferentiability may be hard to see experimentally). The second phenomenon is a violation of the dispersion relations: the susceptibility has singularities in the upper half complex plane. These 'acausal' singularities are actually due to 'energy nonconservation': for a small periodic perturbation of the system, the amplitude of the linear response is arbitrarily large. This means that the NESS of the dynamical system under study is not 'inert' but can give energy to the outside world. An 'active' NESS of this sort is very different from an equilibrium state, and it would be interesting to see what happens for active states to the Gallavotti-Cohen fluctuation theorem.

  17. Understanding and Ameliorating Non-Linear Phase and Amplitude Responses in AMCW Lidar

    Directory of Open Access Journals (Sweden)

    John P. Godbaz

    2011-12-01

    Full Text Available Amplitude modulated continuous wave (AMCW lidar systems commonly suffer from non-linear phase and amplitude responses due to a number of known factors such as aliasing and multipath inteference. In order to produce useful range and intensity information it is necessary to remove these perturbations from the measurements. We review the known causes of non-linearity, namely aliasing, temporal variation in correlation waveform shape and mixed pixels/multipath inteference. We also introduce other sources of non-linearity, including crosstalk, modulation waveform envelope decay and non-circularly symmetric noise statistics, that have been ignored in the literature. An experimental study is conducted to evaluate techniques for mitigation of non-linearity, and it is found that harmonic cancellation provides a significant improvement in phase and amplitude linearity.

  18. Quasilaminar regime in the linear response of a turbulent flow to wall waviness

    Science.gov (United States)

    Luchini, Paolo; Charru, François

    2017-01-01

    The linear response of the wall-shear stress of a turbulent flow to wall waviness is analyzed in the context of a comparison between existing experiments, direct numerical simulations, and analytical approximations. The spectral region where the response is largest is found to be amenable to a simplified quasilaminar analysis. The end result is a parameterless description of this phenomenon that completely captures its physics in a single analytical formula, a Padé approximation of the response function.

  19. Computer Algorithms for the Design and Implementation of Linear Phase Finite Impulse Response Digital Filters

    Science.gov (United States)

    1981-07-01

    1p^^i-J\\\\^3^\\\\^. TECHNICAL LIBRARY AD^y^.q ijg. TECHNICAL REPORT ARBRL-TR-02346 COMPUTER ALGORITHMS FOR THE DESIGN AND IMPLEMENTATION OF LINEAR...INSTRUCTIONS BEFORE COMPLETI?>G FORM 1. REPORT NUMBER TECHNICAL REPORT ARBRL-TR-n2.^46 i. GOVT ACCESSION NO. *. TITLE fand Sijfam;»; COMPUTER ... ALGORITHMS FOR THE DESIGN AND IMPLEMENTATION OF LINEAR PHASE FINPTE IMPULSE RESPONSE DIGITAL FILTERS 7. AUTHORf*; James N. Walbert 9

  20. Frequency Response of Synthetic Vocal Fold Models with Linear and Nonlinear Material Properties

    Science.gov (United States)

    Shaw, Stephanie M.; Thomson, Scott L.; Dromey, Christopher; Smith, Simeon

    2014-01-01

    Purpose The purpose of this study was to create synthetic vocal fold models with nonlinear stress-strain properties and to investigate the effect of linear versus nonlinear material properties on fundamental frequency during anterior-posterior stretching. Method Three materially linear and three materially nonlinear models were created and stretched up to 10 mm in 1 mm increments. Phonation onset pressure (Pon) and fundamental frequency (F0) at Pon were recorded for each length. Measurements were repeated as the models were relaxed in 1 mm increments back to their resting lengths, and tensile tests were conducted to determine the stress-strain responses of linear versus nonlinear models. Results Nonlinear models demonstrated a more substantial frequency response than did linear models and a more predictable pattern of F0 increase with respect to increasing length (although range was inconsistent across models). Pon generally increased with increasing vocal fold length for nonlinear models, whereas for linear models, Pon decreased with increasing length. Conclusions Nonlinear synthetic models appear to more accurately represent the human vocal folds than linear models, especially with respect to F0 response. PMID:22271874

  1. Introduction of non-linear elasticity models for characterization of shape and deformation statistics: application to contractility assessment of isolated adult cardiocytes.

    Science.gov (United States)

    Bazan, Carlos; Hawkins, Trevor; Torres-Barba, David; Blomgren, Peter; Paolini, Paul

    2011-08-22

    We are exploring the viability of a novel approach to cardiocyte contractility assessment based on biomechanical properties of the cardiac cells, energy conservation principles, and information content measures. We define our measure of cell contraction as being the distance between the shapes of the contracting cell, assessed by the minimum total energy of the domain deformation (warping) of one cell shape into another. To guarantee a meaningful vis-à-vis correspondence between the two shapes, we employ both a data fidelity term and a regularization term. The data fidelity term is based on nonlinear features of the shapes while the regularization term enforces the compatibility between the shape deformations and that of a hyper-elastic material. We tested the proposed approach by assessing the contractile responses in isolated adult rat cardiocytes and contrasted these measurements against two different methods for contractility assessment in the literature. Our results show good qualitative and quantitative agreements with these methods as far as frequency, pacing, and overall behavior of the contractions are concerned. We hypothesize that the proposed methodology, once appropriately developed and customized, can provide a framework for computational cardiac cell biomechanics that can be used to integrate both theory and experiment. For example, besides giving a good assessment of contractile response of the cardiocyte, since the excitation process of the cell is a closed system, this methodology can be employed in an attempt to infer statistically significant model parameters for the constitutive equations of the cardiocytes.

  2. Linear response theory for symmetry improved two particle irreducible effective actions

    Science.gov (United States)

    Brown, Michael J.; Whittingham, Ian B.; Kosov, Daniel S.

    2016-05-01

    We investigate the linear response of an O (N ) scalar quantum field theory subject to external perturbations using the symmetry-improved two-particle irreducible effective action (SI-2PIEA) formalism [A. Pilaftsis and D. Teresi, Nucl. Phys. B874, 594 (2013)]. Despite satisfactory equilibrium behavior, we find a number of unphysical effects at the linear response level. Goldstone boson field fluctuations are overdetermined, with the only consistent solution being to set the fluctuations and their driving sources to zero, except for momentum modes where the Higgs and Goldstone self-energies obey a particular relationship. Also Higgs field fluctuations propagate masslessly, despite the Higgs propagator having the correct mass. These pathologies are independent of any truncation of the effective action and still exist even if we relax the overdetermining Ward identities, so long as the constraint is formulated O (N ) covariantly. We discuss possible reasons for the apparent incompatibility of the constraints and linear response approximation and possible ways forward.

  3. Determining the continuous family of quantum Fisher information from linear-response theory

    Science.gov (United States)

    Shitara, Tomohiro; Ueda, Masahito

    2016-12-01

    The quantum Fisher information represents a continuous family of metrics on the space of quantum states and places the fundamental limit on the accuracy of quantum state estimation. We show that the entire family of quantum Fisher information can be determined from linear-response theory through generalized covariances. We derive the generalized fluctuation-dissipation theorem that relates linear-response functions to generalized covariances and hence allows us to determine the quantum Fisher information from linear-response functions, which are experimentally measurable quantities. As an application, we examine the skew information, which is a quantum Fisher information, of a harmonic oscillator in thermal equilibrium, and show that the equality of the skew-information-based uncertainty relation holds.

  4. Nonlinear system stochastic response determination via fractional equivalent linearization and Karhunen-Loève expansion

    Science.gov (United States)

    Dai, Hongzhe; Zheng, Zhibao; Wang, Wei

    2017-08-01

    In this paper, a novel fractional equivalent linearization (EL) approach is developed by incorporating a fractional derivative term into the classical linearization equation. Due to the introduction of the fractional derivative term, the accuracy of the new linearization is improved, illustrated by a Duffing oscillator that is subjected to a harmonic excitation. Furthermore, a new method for solving stochastic response of nonlinear SDOF system is developed by combining Karhunen-Loève (K-L) expansion and fractional EL. The method firstly decomposes the stochastic excitation in terms of a set of random variables and deterministic sub-excitations using K-L expansion, and then construct sub-fractional equivalent linear system according to each sub-excitation by fractional EL, the response of the original nonlinear system is finally approximated as the weighed summation of the deterministic response of each sub-system multiplied by the corresponding random variable. The random nature of the final response comes from the set of random variables that is obtained in K-L expansion. In this way, the stochastic response computation is converted to a set of deterministic response analysis problems. The effectiveness of the developed method is demonstrated by a Duffing oscillator that is subjected to stochastic excitation modeled by Winner process. The results are compared with the numerical method and Monte Carlo simulation (MCS).

  5. The linearity response of the Planck-LFI flight model receivers

    Energy Technology Data Exchange (ETDEWEB)

    Mennella, A; Bersanelli, M [Universita degli Studi di Milano, Dipartimento di Fisica, Via Celoria 16, 20133 Milano (Italy); Villa, F; Terenzi, L; Cuttaia, F; Butler, R C [INAF-IASF Bologna, Via P.Gobetti 101, 40129 Bologna (Italy); Battaglia, P; Franceschet, C; Lapolla, P M [Thales Alenia Space - Italia, S.S. Padana Superiore 290, 20090 Vimodrone, Milano (Italy); D' Arcangelo, O [CNR, Istituto di Fisica del Plasma, Via Roberto Cozzi 53, 20125 Milano (Italy); Artal, E [Departamento de Ingenieria de Comunicaciones, Universidad de Cantabria, Avenida de los Castros s/n. 39005 Santander (Spain); Davis, R; Kettle, D [Jodrell Bank Centre for Astrophysics, University of Manchester, M13 9PL (United Kingdom); Frailis, M; Galeotta, S [INAF - Osservatorio Astronomico di Trieste, Via Tiepolo 11, 34012 Trieste (Italy); Gregorio, A [Universita degli Studi di Trieste, Dipartimenti di fisica Via Valerio 2, 34127 Trieste (Italy); Hughes, N; Jukkala, P; Kilpiae, V-H [DA-Design Oj, Keskuskatu 29, FI-31600 Jokioinen (Finland); Laaninen, M, E-mail: aniello.mennella@fisica.unimi.i [Ylinen Electronics Oy, Teollisuustie 9A, FIN-02700 Kauniainen (Finland)

    2009-12-15

    In this paper we discuss the linearity response of the Planck-LFI receivers, with particular reference to signal compression measured on the 30 and 44 GHz channels. In the article we discuss the various sources of compression and present a model that accurately describes data measured during tests performed with individual radiomeric chains. After discussing test results we present the best parameter set representing the receiver response and discuss the impact of non linearity on in-flight calibration, which is shown to be negligible.

  6. Hydrodynamic theory for quantum plasmonics: Linear-response dynamics of the inhomogeneous electron gas

    DEFF Research Database (Denmark)

    Yan, Wei

    2015-01-01

    We investigate the hydrodynamic theory of metals, offering systematic studies of the linear-response dynamics for an inhomogeneous electron gas. We include the quantum functional terms of the Thomas-Fermi kinetic energy, the von Weizsa¨cker kinetic energy, and the exchange-correlation Coulomb...... response of complex metallic nanostructures, including quantum effects, by adjusting theory parameters appropriately....... energies under the local density approximation. The advantages, limitations, and possible improvements of the hydrodynamic theory are transparently demonstrated. The roles of various parameters in the theory are identified. We anticipate that the hydrodynamic theory can be applied to investigate the linear...

  7. Characteristics of identifying linear dynamic models from impulse response data using Prony analysis

    Energy Technology Data Exchange (ETDEWEB)

    Trudnowski, D.J.

    1992-12-01

    The purpose of the study was to investigate the characteristics of fitting linear dynamic models to the impulse response of oscillatory dynamic systems using Prony analysis. Many dynamic systems exhibit oscillatory responses with multiple modes of oscillations. Although the underlying dynamics of such systems are often nonlinear, it is frequently possible and very useful to represent the system operating about some set point with a linear model. Derivation of such linear models can be done using two basic approaches: model the system using theoretical derivations and some linearization method such as a Taylor series expansion; or use a curve-fitting technique to optimally fit a linear model to specified system response data. Prony analysis belongs to the second class of system modeling because it is a method of fitting a linear model to the impulse response of a dynamic system. Its parallel formulation inherently makes it well suited for fitting models to oscillatory system data. Such oscillatory dynamic effects occur in large synchronous-generator-based power systems in the form of electromechanical oscillations. To study and characterize these oscillatory dynamics, BPA has developed computer codes to analyze system data using Prony analysis. The objective of this study was to develop a highly detailed understanding of the properties of using Prony analysis to fit models to systems with characteristics often encountered in power systems. This understanding was then extended to develop general ``rules-of-thumb`` for using Prony analysis. The general characteristics were investigated by performing fits to data from known linear models under controlled conditions. The conditions studied include various mathematical solution techniques; different parent system configurations; and a large variety of underlying noise characteristics.

  8. Characteristics of identifying linear dynamic models from impulse response data using Prony analysis

    Energy Technology Data Exchange (ETDEWEB)

    Trudnowski, D.J.

    1992-12-01

    The purpose of the study was to investigate the characteristics of fitting linear dynamic models to the impulse response of oscillatory dynamic systems using Prony analysis. Many dynamic systems exhibit oscillatory responses with multiple modes of oscillations. Although the underlying dynamics of such systems are often nonlinear, it is frequently possible and very useful to represent the system operating about some set point with a linear model. Derivation of such linear models can be done using two basic approaches: model the system using theoretical derivations and some linearization method such as a Taylor series expansion; or use a curve-fitting technique to optimally fit a linear model to specified system response data. Prony analysis belongs to the second class of system modeling because it is a method of fitting a linear model to the impulse response of a dynamic system. Its parallel formulation inherently makes it well suited for fitting models to oscillatory system data. Such oscillatory dynamic effects occur in large synchronous-generator-based power systems in the form of electromechanical oscillations. To study and characterize these oscillatory dynamics, BPA has developed computer codes to analyze system data using Prony analysis. The objective of this study was to develop a highly detailed understanding of the properties of using Prony analysis to fit models to systems with characteristics often encountered in power systems. This understanding was then extended to develop general rules-of-thumb'' for using Prony analysis. The general characteristics were investigated by performing fits to data from known linear models under controlled conditions. The conditions studied include various mathematical solution techniques; different parent system configurations; and a large variety of underlying noise characteristics.

  9. Segmented Polyurethane Nanocomposites: Impact of Controlled Particle Size Nanofillers on the Morphological Response to Uniaxial Deformation

    Energy Technology Data Exchange (ETDEWEB)

    Finnigan, Bradley; Jack, Kevin; Campbell, Kayleen; Halley, Peter; Truss, Rowan; Casey, Phil; Cookson, David; King, Stephen; Martin, Darren (Rutherford); (ASRP); (Queensland); (CSIRO)

    2008-10-03

    A series of TPU nanocomposites were prepared by incorporating organically modified layered silicates with controlled particle size. To our knowledge, this is the first study into the effects of layered silicate diameter in polymer nanocomposites utilizing the same mineral for each size fraction. The tensile properties of these materials were found to be highly dependent upon the size of the layered silicates. A decrease in disk diameter was associated with a sharp upturn in the stress-strain curve and a pronounced increase in tensile strength. Results from SAXS/SANS experiments showed that the layered silicates did not affect the bulk TPU microphase structure and the morphological response of the host TPU to deformation or promote/hinder strain-induced soft segment crystallization. The improved tensile properties of the nanocomposites containing the smaller nanofillers resulted from the layered silicates aligning in the direction of strain and interacting with the TPU sequences via secondary bonding. This phenomenon contributes predominantly above 400% strain once the microdomain architecture has largely been disassembled. Large tactoids that are unable to align in the strain direction lead to concentrated tensile stresses between the polymer and filler, instead of desirable shear stresses, resulting in void formation and reduced tensile properties. In severe cases, such as that observed for the composite containing the largest silicate, these voids manifest visually as stress whitening.

  10. Microscale modeling of fluid flow-geomechanics-seismicity: Relationship between permeability and seismic source response in deformed rock joints

    Science.gov (United States)

    Raziperchikolaee, S.; Alvarado, V.; Yin, S.

    2014-09-01

    Studying rock joint deformation including both slippage and opening mechanisms provides an opportunity to investigate the connection between the permeability and seismic source mechanisms. A microscale fluid flow-geomechanics-seismicity model was built to evaluate the transport response and failure mechanism of microcracks developed along a joint in Berea sandstone samples during deformation. The modeling method considers comprehensive grain-cement interactions. Fluid flow behavior is obtained through a realistic network model of the pore space in the compacted assembly. The geometric description of the complex pore structure is characterized to predict permeability of the rock sample as a function of rock deformation by using a dynamic pore network model. As a result of microcracks development, forces and displacements in grains involved in bond breakage are measured to determine seismic moment tensor. Shear and nonshear displacements are applied to the joint samples to investigate their effects on permeability evolution and failure mechanism of microcracks during joint deformation. In addition, the effect of joint roughness is analyzed by performing numerical compression tests. We also investigate how confining pressure affects volumetric deformation leading to opening or closure of developed microcracks and permeability changes of samples with joints.

  11. Experimental Validation of Two-dimensional Finite Element Method for Simulating Constitutive Response of Polycrystals During High Temperature Plastic Deformation

    Science.gov (United States)

    Agarwal, Sumit; Briant, Clyde L.; Krajewski, Paul E.; Bower, Allan F.; Taleff, Eric M.

    2007-04-01

    A finite element method was recently designed to model the mechanisms that cause superplastic deformation (A.F. Bower and E. Wininger, A Two-Dimensional Finite Element Method for Simulating the Constitutive Response and Microstructure of Polycrystals during High-Temperature Plastic Deformation, J. Mech. Phys. Solids, 2004, 52, p 1289-1317). The computations idealize the solid as a collection of two-dimensional grains, separated by sharp grain boundaries. The grains may deform plastically by thermally activated dislocation motion, which is modeled using a conventional crystal plasticity law. The solid may also deform by sliding on the grain boundaries, or by stress-driven diffusion of atoms along grain boundaries. The governing equations are solved using a finite element method, which includes a front-tracking procedure to monitor the evolution of the grain boundaries and surfaces in the solid. The goal of this article is to validate these computations by systematically comparing numerical predictions to experimental measurements of the elevated-temperature response of aluminum alloy AA5083 (M.-A. Kulas, W.P. Green, E.M. Taleff, P.E. Krajewski, and T.R. McNelley, Deformation Mechanisms in Superplastic AA5083 materials. Metall. Mater. Trans. A, 2005, 36(5), p 1249-1261). The experimental work revealed that a transition occurs from grain-boundary sliding to dislocation (solute-drag) creep at approximately 0.001/s for temperatures between 425 and 500 °C. In addition, increasing the grain size from 7 to 10 μm decreased the transition to significantly lower strain rates. Predictions from the finite element method accurately predict the effect of grain size on the transition in deformation mechanisms.

  12. Flutter and Forced Response Analyses of Cascades using a Two-Dimensional Linearized Euler Solver

    Science.gov (United States)

    Reddy, T. S. R.; Srivastava, R.; Mehmed, O.

    1999-01-01

    Flutter and forced response analyses for a cascade of blades in subsonic and transonic flow is presented. The structural model for each blade is a typical section with bending and torsion degrees of freedom. The unsteady aerodynamic forces due to bending and torsion motions. and due to a vortical gust disturbance are obtained by solving unsteady linearized Euler equations. The unsteady linearized equations are obtained by linearizing the unsteady nonlinear equations about the steady flow. The predicted unsteady aerodynamic forces include the effect of steady aerodynamic loading due to airfoil shape, thickness and angle of attack. The aeroelastic equations are solved in the frequency domain by coupling the un- steady aerodynamic forces to the aeroelastic solver MISER. The present unsteady aerodynamic solver showed good correlation with published results for both flutter and forced response predictions. Further improvements are required to use the unsteady aerodynamic solver in a design cycle.

  13. Linear Response Theory for Symmetry Improved Two Particle Irreducible Effective Actions

    CERN Document Server

    Brown, Michael J; Kosov, Daniel S

    2016-01-01

    We investigate the linear response of an O(N) scalar quantum field theory subject to external perturbations using the symmetry improved two particle irreducible effective action formalism [A. Pilaftsis and D. Teresi, Nucl. Phys. B874, 594 (2013)]. Despite satisfactory equilibrium behavior, we find a number of unphysical effects at the linear response level. Goldstone boson field fluctuations are over-determined, with the only consistent solution being to set the fluctuations and their driving sources to zero, except for momentum modes where the Higgs and Goldstone self-energies obey a particular relationship. Also Higgs field fluctuations propagate masslessly, despite the Higgs propagator having the correct mass. These pathologies are independent of any truncation of the effective action and still exist even if we relax the over-determining Ward identities, so long as the constraint is formulated O(N)-covariantly. We discuss possible reasons for the apparent incompatibility of the constraints and linear respo...

  14. A study of non-linearity in rainfall-runoff response using 120 UK catchments

    Science.gov (United States)

    Mathias, Simon A.; McIntyre, Neil; Oughton, Rachel H.

    2016-09-01

    This study presents a catchment characteristic sensitivity analysis concerning the non-linearity of rainfall-runoff response in 120 UK catchments. Two approaches were adopted. The first approach involved, for each catchment, regression of a power-law to flow rate gradient data for recession events only. This approach was referred to as the recession analysis (RA). The second approach involved calibrating a rainfall-runoff model to the full data set (both recession and non-recession events). The rainfall-runoff model was developed by combining a power-law streamflow routing function with a one parameter probability distributed model (PDM) for soil moisture accounting. This approach was referred to as the rainfall-runoff model (RM). Step-wise linear regression was used to derive regionalization equations for the three parameters. An advantage of the RM approach is that it utilizes much more of the observed data. Results from the RM approach suggest that catchments with high base-flow and low annual precipitation tend to exhibit greater non-linearity in rainfall-runoff response. In contrast, the results from the RA approach suggest that non-linearity is linked to low evaporative demand. The difference in results is attributed to the aggregation of storm-flow and base-flow into a single system giving rise to a seemingly more non-linear response when applying the RM approach to catchments that exhibit a strongly dual storm-flow base-flow response. The study also highlights the value and limitations in a regionlization context of aggregating storm-flow and base-flow pathways into a single non-linear routing function.

  15. Ab initio calculation of the Gilbert damping parameter via the linear response formalism

    NARCIS (Netherlands)

    Ebert, H.; Mankovsky, S.; Ködderitzsch, D.; Kelly, Paul J.

    2011-01-01

    A Kubo-Greenwood-like equation for the Gilbert damping parameter α is presented that is based on the linear response formalism. Its implementation using the fully relativistic Korringa-Kohn-Rostoker band structure method in combination with coherent potential approximation alloy theory allows it to

  16. Stochastic Response of an Inclined Shallow Cable with Linear Viscous Dampers under Stochastic Excitation

    DEFF Research Database (Denmark)

    Zhou, Qiang; Nielsen, Søren R.K.; Qu, Weilian

    2010-01-01

    Considering the coupling between the in-plane and out-of-plane vibration, the stochastic response of an inclined shallow cable with linear viscous dampers subjected to Gaussian white noise excitation is investigated in this paper. Selecting the static deflection shape due to a concentrated force ...

  17. Linear response in aging glassy systems, intermittency and the Poisson statistics of record fluctuations

    DEFF Research Database (Denmark)

    Sibani, Paolo

    2007-01-01

    We study the intermittent behavior of the energy decay and the linear magnetic response of a glassy system during isothermal aging after a deep thermal quench, using the Edward-Anderson spin glass model as a paradigmatic example. The large intermittent changes in the two observables occur in a co...

  18. Determining polarizable force fields with electrostatic potentials from quantum mechanical linear response theory.

    Science.gov (United States)

    Wang, Hao; Yang, Weitao

    2016-06-14

    We developed a new method to calculate the atomic polarizabilities by fitting to the electrostatic potentials (ESPs) obtained from quantum mechanical (QM) calculations within the linear response theory. This parallels the conventional approach of fitting atomic charges based on electrostatic potentials from the electron density. Our ESP fitting is combined with the induced dipole model under the perturbation of uniform external electric fields of all orientations. QM calculations for the linear response to the external electric fields are used as input, fully consistent with the induced dipole model, which itself is a linear response model. The orientation of the uniform external electric fields is integrated in all directions. The integration of orientation and QM linear response calculations together makes the fitting results independent of the orientations and magnitudes of the uniform external electric fields applied. Another advantage of our method is that QM calculation is only needed once, in contrast to the conventional approach, where many QM calculations are needed for many different applied electric fields. The molecular polarizabilities obtained from our method show comparable accuracy with those from fitting directly to the experimental or theoretical molecular polarizabilities. Since ESP is directly fitted, atomic polarizabilities obtained from our method are expected to reproduce the electrostatic interactions better. Our method was used to calculate both transferable atomic polarizabilities for polarizable molecular mechanics' force fields and nontransferable molecule-specific atomic polarizabilities.

  19. A Capacitor-Free, Fast Transient Response Linear Voltage Regulator In a 180nm CMOS

    DEFF Research Database (Denmark)

    Deleuran, Alexander N.; Lindbjerg, Nicklas; Pedersen, Martin K.;

    2015-01-01

    A 1.8 V capacitor-free linear regulator with fast transient response based on a new topology with a fast and slow regulation loop is presented. The design has been laid out and simulated in a 0.18 µm CMOS process. The design has a low component count and is tailored for system-on-chip integration...

  20. A discrete solvent reaction field model for calculating molecular linear response properties in solution

    NARCIS (Netherlands)

    Jensen, L; van Duijnen, PT; Snijders, JG

    2003-01-01

    A discrete solvent reaction field model for calculating frequency-dependent molecular linear response properties of molecules in solution is presented. The model combines a time-dependent density functional theory (QM) description of the solute molecule with a classical (MM) description of the discr

  1. Effective grouting area of jointed slope and stress deformation responses by numerical analysis with FLAC3D

    Institute of Scientific and Technical Information of China (English)

    ZHU Zi-qiang; LIU Qun-yi; ZENG Fan-he; QING Du-gan

    2009-01-01

    To study the grouting reinforcement mechanism in jointed rock slope, first, the theoretical deduction was done to calculate the critical length of slipping if the slope angle is larger than that of joint inclination; Second, the numerical calculation model was founded by FLAG3D, so as to find the stress and deformation responses of rock mass in the state before and after grouting, the analysis results show that the range between the boundary of critical slipping block and the joint plane that passes the slope toe is the effective grouting area (EGA). After excavation, large deformation occurs along the joint plane. After grouting, the displacements of rock particles become uniform and continuous, and large deformations along the joint plane are controlled; the dynamic displacement can reflect the deformation response of slope during excavation in the state before and after grouting, as well as the shear location of potential slip plane. After grouting, the dynamic displacement of each monitoring point reaches the peak value with very few time steps,which indicate that the parameters of the joint plane, such as strength and stiffness, are improved; the stress field becomes uniform. Tensile area reduces gradually; whole stability of the slope and its ability to resist tensile and shear stress are improved greatly.

  2. Non-linear response of soil carbon gas (CO2, CH4) flux to oxygen availability

    Science.gov (United States)

    Mcnicol, G.; Silver, W. L.

    2013-12-01

    Soil oxygen (O2) concentration can impact soil carbon (C) fluxes of carbon dioxide (CO2) and methane (CH4), and is an important chemical gradient across the terrestrial-aquatic interface that drives large differences in ecosystem C storage. Few studies have established quantitative relationships between gas-phase O2 concentration and soil C fluxes in controlled settings. Though standard Michaelis-Menten enzyme kinetics would predict a highly non-linear relationship between O2 concentration and microbial consumption, existing studies have imposed coarse changes in O2 concentration that necessarily prevent detection of non-linearity. We report on the results of laboratory incubations designed to explore the short-term sensitivity of soil C emissions to a wide range of gas-phase O2 concentrations. Organic-rich soil was collected from a drained peatland and subjected to seven O2 concentration treatments ranging from 0.03 % - 20 % O2. We compared the fit of the observed C flux response to O2 concentration to linear, log-linear, and Michaelis-Menten functions using MSE and residual fits as performance metrics. We found that both CO2 and CH4 emissions were highly sensitive to O2 concentration, with emission rates increasing and decreasing, respectively, at higher O2. Net CH4 emission rates were attenuated at higher O2 concentrations most likely due to stimulation of gross CH4 consumption. A log-linear or Michaelis-Menten model better fit data than a linear model by both performance metrics, demonstrating, empirically, a non-linear relationship between O2 concentration and soil CO2 and CH4 fluxes. Our results suggest high O2 sensitivity of C-rich soils at the terrestrial-aquatic interface and show that the microbial response to soil redox chemistry must be measured over a biophysically meaningful range of conditions to derive relationships that accurately predict soil C fluxes.

  3. Unified Approach to Thermodynamic Optimization of Generic Objective Functions in the Linear Response Regime

    Directory of Open Access Journals (Sweden)

    Yan Wang

    2016-04-01

    Full Text Available While many efforts have been devoted to optimizing the power output for a finite-time thermodynamic process, thermodynamic optimization under realistic situations is not necessarily concerned with power alone; rather, it may be of great relevance to optimize generic objective functions that are combinations of power, entropy production, and/or efficiency. One can optimize the objective function for a given model; generally the obtained results are strongly model dependent. However, if the thermodynamic process in question is operated in the linear response regime, then we show in this work that it is possible to adopt a unified approach to optimizing the objective function, thanks to Onsager’s theory of linear irreversible thermodynamics. A dissipation bound is derived, and based on it, the efficiency associated with the optimization problem, which is universal in the linear response regime and irrespective of model details, can be obtained in a unified way. Our results are in good agreement with previous findings. Moreover, we unveil that the ratio between the stopping time of a finite-time process and the optimized duration time plays a pivotal role in determining the corresponding efficiency in the case of linear response.

  4. Calculation of static and dynamic linear magnetic response in approximate time-dependent density functional theory.

    Science.gov (United States)

    Krykunov, Mykhaylo; Autschbach, Jochen

    2007-01-14

    We report implementations and results of time-dependent density functional calculations (i) of the frequency-dependent magnetic dipole-magnetic dipole polarizability, (ii) of the (observable) translationally invariant linear magnetic response, and (iii) of a linear intensity differential (LID) which includes the dynamic dipole magnetizability. The density functional calculations utilized density fitting. For achieving gauge-origin independence we have employed time-periodic magnetic-field-dependent basis functions as well as the dipole velocity gauge, and have included explicit density-fit related derivatives of the Coulomb potential. We present the results of calculations of static and dynamic magnetic dipole-magnetic dipole polarizabilities for a set of small molecules, the LID for the SF6 molecule, and dispersion curves for M-hexahelicene of the origin invariant linear magnetic response as well as of three dynamic polarizabilities: magnetic dipole-magnetic dipole, electric dipole-electric dipole, and electric dipole-magnetic dipole. We have also performed comparison of the linear magnetic response and magnetic dipole-magnetic dipole polarizability over a wide range of frequencies for H2O and SF6.

  5. Linear and quadratic static response functions and structure functions in Yukawa liquids.

    Science.gov (United States)

    Magyar, Péter; Donkó, Zoltán; Kalman, Gabor J; Golden, Kenneth I

    2014-08-01

    We compute linear and quadratic static density response functions of three-dimensional Yukawa liquids by applying an external perturbation potential in molecular dynamics simulations. The response functions are also obtained from the equilibrium fluctuations (static structure factors) in the system via the fluctuation-dissipation theorems. The good agreement of the quadratic response functions, obtained in the two different ways, confirms the quadratic fluctuation-dissipation theorem. We also find that the three-point structure function may be factorizable into two-point structure functions, leading to a cluster representation of the equilibrium triplet correlation function.

  6. Non-linear wave loads and ship responses by a time-domain strip theory

    DEFF Research Database (Denmark)

    Xia, Jinzhu; Wang, Zhaohui; Jensen, Jørgen Juncher

    1998-01-01

    A non-linear time-domain strip theory for vertical wave loads and ship responses is presented. The theory is generalized from a rigorous linear time-domain strip theory representation. The hydrodynamic memory effect due to the free surface is approximated by a higher order differential equation. ...... and are systematically compared with the experimental results given by Watanabe et al. (1989, J. Soc. Naval Architects Japan, 166) and O’Dea et al. (1992, Proc. 19th Symp. on Naval Hydrodynamics). The agreement between the present predictions and the experiments is very encouraging....

  7. Experimental and Analytical Analysis of Mechanical Response and Deformation Mode Selection in Balsa Wood

    Science.gov (United States)

    Vural, Murat; Ravichandran, Guruswami

    This study investigates the influence of relative density and strain rate on the compressive response of balsa wood as a sandwich core material commonly used in naval structures. Compressive strength, plateau stress and densification strain of balsa wood along the grain direction is investigated over its entire density spectrum ranging from 55 to 380kg/m3 at both quasi-static (10-3 s-3) and dynamic (103 s-3) strain rates using a modified Kolsky (split Hopkinson) bar. Scanning electron microscopy is used on recovered specimens subjected to controlled loading histories to identify the failure mode selection as a function of density and strain rate. The results indicate that compressive strength of balsa wood increases with relative density though the rate of increase is significantly larger at high strain rates. The failure of low-density specimens is governed by elastic and/or plastic buckling, while kink band formation and end-cap collapse dominate in higher density balsa specimens. Based on the experimental results and observations, several analytical models are proposed to predict the quasi-static compressive strength of balsa wood under uniaxial loading conditions. Results also show that the initial failure stress is very sensitive to the rate of loading, and the degree of dynamic strength enhancement is different for buckling and kink band modes. Kinematics of deformation of the observed failure modes and associated micro-inertial effects are modeled to explain this different behavior. Specific energy dissipation capacity of balsa wood was computed and is found to be comparable with those of fiber-reinforced polymer composites.

  8. Log-linear randomized-response models taking self-protective response behavior into account

    NARCIS (Netherlands)

    Cruyff, M.J.L.F; Hout, Ardo van den; Heijden, P.G.M. van der; Böckenholt, Ulf

    2007-01-01

    Randomized response (RR) is an interview technique designed to eliminate response bias when sensitive questions are asked. In RR the answer depends partly on the true status of the respondent and partly on the outcome of a randomizing device. Although RR elicits more honest answers than direct quest

  9. Procedure for preventing response strain on random interval schedules with a linear feedback loop.

    Science.gov (United States)

    Reed, Phil

    2016-03-01

    An experiment examined the impact of a procedure designed to prevent response or extinction strain occurring on random interval schedules with a linear feedback loop (i.e., an RI+ schedule). Rats lever-pressed for food reinforcement on either a RI+ or a random interval (RI) schedule that was matched to the RI+ schedule in terms of reinforcement rate. Two groups of rats responded on an RI+ and two on an RI schedule matched for rate of reinforcement. One group on each schedule also received response-independent food if there had been no response for 60 s, and response-independent food continued to be delivered on an RT-60 schedule until a response was made. Rats on the RI and RI+ obtained similar rates of reinforcement and had similar reinforced inter-response times to one another. On the schedules without response-independent food, rats had similar rates of response to one another. However, while the delivery of response-independent food reduced rates of response on an RI schedule, they enhanced response rates on an RI+ schedule. These results suggest that rats can display sensitivity to the molar aspects of the free-operant contingency, when procedures are implemented to reduce the impact of factors such as extinction-strain.

  10. Low voltage RF MEMS variable capacitor with linear C-V response

    KAUST Repository

    Elshurafa, Amro M.

    2012-07-23

    An RF MEMS variable capacitor, fabricated in the PolyMUMPS process and tuned electrostatically, possessing a linear capacitance-voltage response is reported. The measured quality factor of the device was 17 at 1GHz, while the tuning range was 1.2:1 and was achieved at an actuation DC voltage of 8V only. Further, the linear regression coefficient was 0.98. The variable capacitor was created such that it has both vertical and horizontal capacitances present. As the top suspended plate moves towards the bottom fixed plate, the vertical capacitance increases whereas the horizontal capacitance decreases simultaneously such that the sum of the two capacitances yields a linear capacitance-voltage relation. © 2012 The Institution of Engineering and Technology.

  11. Improving linear accelerator service response with a real- time electronic event reporting system.

    Science.gov (United States)

    Hoisak, Jeremy D P; Pawlicki, Todd; Kim, Gwe-Ya; Fletcher, Richard; Moore, Kevin L

    2014-09-08

    To track linear accelerator performance issues, an online event recording system was developed in-house for use by therapists and physicists to log the details of technical problems arising on our institution's four linear accelerators. In use since October 2010, the system was designed so that all clinical physicists would receive email notification when an event was logged. Starting in October 2012, we initiated a pilot project in collaboration with our linear accelerator vendor to explore a new model of service and support, in which event notifications were also sent electronically directly to dedicated engineers at the vendor's technical help desk, who then initiated a response to technical issues. Previously, technical issues were reported by telephone to the vendor's call center, which then disseminated information and coordinated a response with the Technical Support help desk and local service engineers. The purpose of this work was to investigate the improvements to clinical operations resulting from this new service model. The new and old service models were quantitatively compared by reviewing event logs and the oncology information system database in the nine months prior to and after initiation of the project. Here, we focus on events that resulted in an inoperative linear accelerator ("down" machine). Machine downtime, vendor response time, treatment cancellations, and event resolution were evaluated and compared over two equivalent time periods. In 389 clinical days, there were 119 machine-down events: 59 events before and 60 after introduction of the new model. In the new model, median time to service response decreased from 45 to 8 min, service engineer dispatch time decreased 44%, downtime per event decreased from 45 to 20 min, and treatment cancellations decreased 68%. The decreased vendor response time and reduced number of on-site visits by a service engineer resulted in decreased downtime and decreased patient treatment cancellations.

  12. Linear population allocation by bistable switches in response to transient stimulation.

    Directory of Open Access Journals (Sweden)

    Jaydeep K Srimani

    Full Text Available Many cellular decision processes, including proliferation, differentiation, and phenotypic switching, are controlled by bistable signaling networks. In response to transient or intermediate input signals, these networks allocate a population fraction to each of two distinct states (e.g. OFF and ON. While extensive studies have been carried out to analyze various bistable networks, they are primarily focused on responses of bistable networks to sustained input signals. In this work, we investigate the response characteristics of bistable networks to transient signals, using both theoretical analysis and numerical simulation. We find that bistable systems exhibit a common property: for input signals with short durations, the fraction of switching cells increases linearly with the signal duration, allowing the population to integrate transient signals to tune its response. We propose that this allocation algorithm can be an optimal response strategy for certain cellular decisions in which excessive switching results in lower population fitness.

  13. Linear response to leadership, effective temperature, and decision making in flocks

    Science.gov (United States)

    Pearce, Daniel J. G.; Giomi, Luca

    2016-08-01

    Large collections of autonomously moving agents, such as animals or micro-organisms, are able to flock coherently in space even in the absence of a central control mechanism. While the direction of the flock resulting from this critical behavior is random, this can be controlled by a small subset of informed individuals acting as leaders of the group. In this article we use the Vicsek model to investigate how flocks respond to leadership and make decisions. Using a combination of numerical simulations and continuous modeling we demonstrate that flocks display a linear response to leadership that can be cast in the framework of the fluctuation-dissipation theorem, identifying an effective temperature reflecting how promptly the flock reacts to the initiative of the leaders. The linear response to leadership also holds in the presence of two groups of informed individuals with competing interests, indicating that the flock's behavioral decision is determined by both the number of leaders and their degree of influence.

  14. Deformed General Relativity

    CERN Document Server

    Bojowald, Martin

    2013-01-01

    Deformed special relativity is embedded in deformed general relativity using the methods of canonical relativity and loop quantum gravity. Phase-space dependent deformations of symmetry algebras then appear, which in some regimes can be rewritten as non-linear Poincare algebras with momentum-dependent deformations of commutators between boosts and time translations. In contrast to deformed special relativity, the deformations are derived for generators with an unambiguous physical role, following from the relationship between canonical constraints of gravity with stress-energy components. The original deformation does not appear in momentum space and does not give rise to non-locality issues or problems with macroscopic objects. Contact with deformed special relativity may help to test loop quantum gravity or restrict its quantization ambiguities.

  15. Numerical calculations of the linear response of a gaseous disk to a protoplanet

    Science.gov (United States)

    Korycansky, D. G.; Pollack, J. B.

    1993-01-01

    Numerical calculations of the linear response of a 2D gaseous disk to the perturbations induced by a protoplanet and the corresponding torque are presented. When the pressure gradient is taken into account, torques are increased in disks with gradients in either surface density and sound speed, the effect of the latter being much greater for the same-sized gradient as measured by the power law index. The torques in turn may be used to calculate timescales for orbital migration of protoplanets.

  16. Evidence from retractor bulbi EMG for linearized motor control of conditioned nictitating membrane responses.

    Science.gov (United States)

    Lepora, N F; Mavritsaki, E; Porrill, J; Yeo, C H; Evinger, C; Dean, P

    2007-10-01

    Classical conditioning of nictitating membrane (NM) responses in rabbits is a robust model learning system, and experimental evidence indicates that conditioned responses (CRs) are controlled by the cerebellum. It is unknown whether cerebellar control signals deal directly with the complex nonlinearities of the plant (blink-related muscles and peripheral tissues) or whether the plant is linearized to ensure a simple relation between cerebellar neuronal firing and CR profile. To study this question, the retractor bulbi muscle EMG was recorded with implanted electrodes during NM conditioning. Pooled activity in accessory abducens motoneurons was estimated from spike trains extracted from the EMG traces, and its temporal profile was found to have an approximately Gaussian shape with peak amplitude linearly related to CR amplitude. The relation between motoneuron activity and CR profiles was accurately fitted by a first-order linear filter, with each spike input producing an exponentially decaying impulse response with time constant of order 0.1 s. Application of this first-order plant model to CR data from other laboratories suggested that, in these cases also, motoneuron activity had a Gaussian profile, with time-of-peak close to unconditioned stimulus (US) onset and SD proportional to the interval between conditioned stimulus and US onsets. These results suggest that for conditioned NM responses the cerebellum is presented with a simplified "virtual" plant that is a linearized version of the underlying nonlinear biological system. Analysis of a detailed plant model suggests that one method for linearising the plant would be appropriate recruitment of motor units.

  17. Performance of Thomas-Fermi and linear response approaches in periodic two-dimensional systems

    Energy Technology Data Exchange (ETDEWEB)

    Calderin, L; Stott, M J [Department of Physics, Queen' s University, Kingston, Ontario, K7 L 3N6 (Canada)], E-mail: calderin@physics.queensu.ca, E-mail: stott@mjs.phy.queensu.ca

    2010-04-16

    A study of the performance of Thomas-Fermi and linear response theories in the case of a two-dimensional periodic model system is presented. The calculated density distribution and total energy per unit cell compare very well with exact results except when there is a small number of particles per cell, even though the potential has narrow tight-binding bands. The results supplement earlier findings of Koivisto and Stott for a localized impurity in a two-dimensional uniform gas.

  18. Thermodynamics of the mesoscopic thermoelectric heat engine beyond the linear-response regime

    Science.gov (United States)

    Yamamoto, Kaoru; Hatano, Naomichi

    2015-10-01

    Mesoscopic thermoelectric heat engine is much anticipated as a device that allows us to utilize with high efficiency wasted heat inaccessible by conventional heat engines. However, the derivation of the heat current in this engine seems to be either not general or described too briefly, even inappropriately in some cases. In this paper, we give a clear-cut derivation of the heat current of the engine with suitable assumptions beyond the linear-response regime. It resolves the confusion in the definition of the heat current in the linear-response regime. After verifying that we can construct the same formalism as that of the cyclic engine, we find the following two interesting results within the Landauer-Büttiker formalism: the efficiency of the mesoscopic thermoelectric engine reaches the Carnot efficiency if and only if the transmission probability is finite at a specific energy and zero otherwise; the unitarity of the transmission probability guarantees the second law of thermodynamics, invalidating Benenti et al.'s argument in the linear-response regime that one could obtain a finite power with the Carnot efficiency under a broken time-reversal symmetry [Phys. Rev. Lett. 106, 230602 (2011), 10.1103/PhysRevLett.106.230602]. These results demonstrate how quantum mechanics constrains thermodynamics.

  19. Theoretical Approach to the Gauge Invariant Linear Response Theories for Ultracold Fermi Gases with Pseudogap

    Directory of Open Access Journals (Sweden)

    Hao Guo

    2015-01-01

    Full Text Available Recent experimental progress allows for exploring some important physical quantities of ultracold Fermi gases, such as the compressibility, spin susceptibility, viscosity, optical conductivity, and spin diffusivity. Theoretically, these quantities can be evaluated from suitable linear response theories. For BCS superfluid, it has been found that the gauge invariant linear response theories can be fully consistent with some stringent consistency constraints. When the theory is generalized to stronger than BCS regime, one may meet serious difficulties to satisfy the gauge invariance conditions. In this paper, we try to construct density and spin linear response theories which are formally gauge invariant for a Fermi gas undergoing BCS-Bose-Einstein Condensation (BEC crossover, especially below the superfluid transition temperature Tc. We adapt a particular t-matrix approach which is close to the G0G formalism to incorporate noncondensed pairing in the normal state. We explicitly show that the fundamental constraints imposed by the Ward identities and Q-limit Ward identity are indeed satisfied.

  20. Lanczos-driven coupled-cluster damped linear response theory for molecules in polarizable environments

    DEFF Research Database (Denmark)

    List, Nanna Holmgaard; Coriani, Sonia; Kongsted, Jacob

    2014-01-01

    We present an extension of a previously reported implementation of a Lanczos-driven coupled-cluster (CC) damped linear response approach to molecules in condensed phases, where the effects of a surrounding environment are incorporated by means of the polarizable embedding formalism. We...... are specifically motivated by a twofold aim: (i) computation of core excitations in realistic surroundings and (ii) examination of the effect of the differential response of the environment upon excitation solely related to the CC multipliers (herein denoted the J matrix) in computations of excitation energies...

  1. Stochastic Response of an Inclined Shallow Cable with Linear Viscous Dampers under Stochastic Excitation

    DEFF Research Database (Denmark)

    Zhou, Qiang; Nielsen, Søren R.K.; Qu, Weilian

    2010-01-01

    at the dampers location and the first sine term as shape functions, a reduced four-degree-of-freedom system of nonlinear stochastic ordinary differential equations are derived to describe dynamic response of the cable. Since only polynomial-type terms are contained, the fourth-order cumulant-neglect closure......Considering the coupling between the in-plane and out-of-plane vibration, the stochastic response of an inclined shallow cable with linear viscous dampers subjected to Gaussian white noise excitation is investigated in this paper. Selecting the static deflection shape due to a concentrated force...

  2. Research the dynamical characteristics of slow deformation waves as a rock massif response to explosions during its outworking

    Science.gov (United States)

    Hachay, Olga; Khachay, Oleg; Shipeev, Oleg

    2015-04-01

    As a result of long-term natural geomechanics and geophysical observation data on mines of complex ore rocks, generalization of the non-linear reaction of rock massif to heavy dynamic influences have been established. In addition, pendulum type waves have been observed and the sources of them have been located inside geoblocks of different hierarchic levels (Oparin et al., 2010). At the same time, these waves propagate with wide low (compared with seismic waves) velocity values (Kurlenja et al., 1993; Oparin et al., 2006). Research into the massif state with the use of the dynamic systems theory approach (Naimark et al., 2009; Chulichkov, 2003; Hachay et al., 2010) has been developed to ascertain the criteria of dissipative regimes changing for real rock massifs, which are under heavy man-caused influence. To realize such research we used the data from the seismic record of the Tashtagol mine for the two-year period from June 2006 up to June 2008. We used the space-time coordinates for all dynamic massif event responses, which occurred during that period inside the mine space and for the explosions - values fixed by seismic station energy (Hachay et al., 2010). The phase diagrams of the massif state for the northern and southern parts of the mine space were plotted in coordinates Ev(t) and d(Ev(t))/dt, t - time - in parts of 24 hours, Ev - the dissipated massive seismic energy - in joules. Hachay et al., (2010) analysed the morphology of seismic response phase trajectories on the explosion influences during different serial intervals in the southern part of the mine. In that period, according to data for different explosions in the mine, the majority of the total energy had been injected into the southern part of the mine. Moreover, at the end of 2007, just in the southern part, the strongest rock burst during the whole history of the working mine happened. We developed a new processing method of seismological information in real, which we can use directly in the

  3. Erythrocyte deformability and aggregation responses to intermittent and continuous artificial gravity exposure

    Science.gov (United States)

    Marijke, Grau; Vera, Abeln; Tobias, Vogt; Wilhelm, Bloch; Stefan, Schneider

    2017-02-01

    Artificial gravity protocols are used to improve g-tolerance of aviators and discussed as countermeasure during prolonged space flight. Little is known about the impact of artificial gravity on the red blood cells (RBC). The purpose of the study was to test how artificial gravity affects RBC deformability and aggregation, which are important determinants of microcirculation. Nine male subjects were exposed to two hypergravity protocols using a short arm human centrifuge: a continuous (CONT) protocol with constant +2 Gz for 30 min and an intermittent (INTER) protocol with repeated intervals of +2 Gz and rest. Blood was sampled pre and post interventions to measure basal blood parameters, RBC nitrite, RBC deformability, aggregation, and to determine the shear rate balancing aggregation and disaggregation (γ at dIsc min). To test for orthostasis effects, five male subjects were asked to stay for 46 min, corresponding to the length of the centrifuge protocols, with blood sampling pre and post intervention. Artificial gravity programs did not affect basal blood parameters or RBC nitrite levels; a marker for RBC deformability influencing nitric oxide. The INTER program did not affect any of the tested parameters. The CONT program did not remarkably affect RBC deformability or γ at dIsc min but significantly aggravated aggregation. Orthostasis effects were thus excluded. The results indicate that continuous artificial gravity, especially with higher g-forces applied, may negatively affect the RBC system and that for a prolonged space flight intermittent but not continuous artificial gravity might represent an appropriate countermeasure.

  4. A generalized linear model for estimating spectrotemporal receptive fields from responses to natural sounds.

    Directory of Open Access Journals (Sweden)

    Ana Calabrese

    Full Text Available In the auditory system, the stimulus-response properties of single neurons are often described in terms of the spectrotemporal receptive field (STRF, a linear kernel relating the spectrogram of the sound stimulus to the instantaneous firing rate of the neuron. Several algorithms have been used to estimate STRFs from responses to natural stimuli; these algorithms differ in their functional models, cost functions, and regularization methods. Here, we characterize the stimulus-response function of auditory neurons using a generalized linear model (GLM. In this model, each cell's input is described by: 1 a stimulus filter (STRF; and 2 a post-spike filter, which captures dependencies on the neuron's spiking history. The output of the model is given by a series of spike trains rather than instantaneous firing rate, allowing the prediction of spike train responses to novel stimuli. We fit the model by maximum penalized likelihood to the spiking activity of zebra finch auditory midbrain neurons in response to conspecific vocalizations (songs and modulation limited (ml noise. We compare this model to normalized reverse correlation (NRC, the traditional method for STRF estimation, in terms of predictive power and the basic tuning properties of the estimated STRFs. We find that a GLM with a sparse prior predicts novel responses to both stimulus classes significantly better than NRC. Importantly, we find that STRFs from the two models derived from the same responses can differ substantially and that GLM STRFs are more consistent between stimulus classes than NRC STRFs. These results suggest that a GLM with a sparse prior provides a more accurate characterization of spectrotemporal tuning than does the NRC method when responses to complex sounds are studied in these neurons.

  5. Linearization of dose-response curve of the radiochromic film dosimetry system

    Energy Technology Data Exchange (ETDEWEB)

    Devic, Slobodan; Tomic, Nada; Aldelaijan, Saad; DeBlois, Francois; Seuntjens, Jan; Chan, Maria F.; Lewis, Dave [Medical Physics Unit, McGill University, Montreal, Quebec H3G 1A4 (Canada) and Department of Radiation Oncology, SMBD Jewish General Hospital, McGill University, Montreal, Quebec H3T 1E2 (Canada); Executive Administration for Radiation Protection and Safety Medical Devices Sector, Saudi Food and Drug Authority, Riyadh, Kingdom of Saudi Arabia 13312 (Saudi Arabia); Medical Physics Unit, McGill University, Montreal, Quebec H3G 1A4 (Canada) and Department of Radiation Oncology, SMBD Jewish General Hospital, McGill University, Montreal, Quebec H3T 1E2 (Canada); Medical Physics Unit, McGill University, Montreal, Quebec H3G 1A4 (Canada); Department of Medical Physics, Memorial Sloan-Kettering Cancer Center Basking Ridge, New Jersey 07920 (United States); Ashland Inc., Wayne, New Jersey 07470 (United States)

    2012-08-15

    Purpose: Despite numerous advantages of radiochromic film dosimeter (high spatial resolution, near tissue equivalence, low energy dependence) to measure a relative dose distribution with film, one needs to first measure an absolute dose (following previously established reference dosimetry protocol) and then convert measured absolute dose values into relative doses. In this work, we present result of our efforts to obtain a functional form that would linearize the inherently nonlinear dose-response curve of the radiochromic film dosimetry system. Methods: Functional form [{zeta}= (-1){center_dot}netOD{sup (2/3)}/ln(netOD)] was derived from calibration curves of various previously established radiochromic film dosimetry systems. In order to test the invariance of the proposed functional form with respect to the film model used we tested it with three different GAFCHROMIC Trade-Mark-Sign film models (EBT, EBT2, and EBT3) irradiated to various doses and scanned on a same scanner. For one of the film models (EBT2), we tested the invariance of the functional form to the scanner model used by scanning irradiated film pieces with three different flatbed scanner models (Epson V700, 1680, and 10000XL). To test our hypothesis that the proposed functional argument linearizes the response of the radiochromic film dosimetry system, verification tests have been performed in clinical applications: percent depth dose measurements, IMRT quality assurance (QA), and brachytherapy QA. Results: Obtained R{sup 2} values indicate that the choice of the functional form of the new argument appropriately linearizes the dose response of the radiochromic film dosimetry system we used. The linear behavior was insensitive to both film model and flatbed scanner model used. Measured PDD values using the green channel response of the GAFCHROMIC Trade-Mark-Sign EBT3 film model are well within {+-}2% window of the local relative dose value when compared to the tabulated Cobalt-60 data. It was also

  6. Non-linear resonances in the forced responses of plates. I - Symmetric responses of circular plates

    Science.gov (United States)

    Sridhar, S.; Mook, D. T.; Nayfeh, A. H.

    1975-01-01

    The dynamic analogue of the von Karman equations is used to study the symmetric response of a circular plate to a harmonic excitation when the frequency of the excitation is near one of the natural frequencies. It is shown that, in general, when there is no internal resonance (i.e., the natural frequencies are not commensurable), only the mode having a frequency near that of the excitation is strongly excited (i.e., is needed to represent the response in the first approximation). A clamped, circular plate is used as a numerical example to show that, when there is an internal resonance, more than one of the modes involved in this resonance can be strongly excited; moreover, when more than one mode is strongly excited, the lower modes can dominate the response, even when the frequency of the excitation is near that of the highest mode. This possibility was not revealed by any of the earlier studies which were based on the same governing equations.

  7. SANTOS - a two-dimensional finite element program for the quasistatic, large deformation, inelastic response of solids

    Energy Technology Data Exchange (ETDEWEB)

    Stone, C.M.

    1997-07-01

    SANTOS is a finite element program designed to compute the quasistatic, large deformation, inelastic response of two-dimensional planar or axisymmetric solids. The code is derived from the transient dynamic code PRONTO 2D. The solution strategy used to compute the equilibrium states is based on a self-adaptive dynamic relaxation solution scheme, which is based on explicit central difference pseudo-time integration and artificial mass proportional damping. The element used in SANTOS is a uniform strain 4-node quadrilateral element with an hourglass control scheme to control the spurious deformation modes. Finite strain constitutive models for many common engineering materials are included. A robust master-slave contact algorithm for modeling sliding contact is implemented. An interface for coupling to an external code is also provided. 43 refs., 22 figs.

  8. The Linear Stability of the Responses of Axially Moving Beams Supported by an Intermediate Spring

    Directory of Open Access Journals (Sweden)

    Kostekci F.

    2016-01-01

    Full Text Available In the present paper, the stability investigation of the linear responses of axially travelling beams supported by an intermediate linear spring is performed numerically by means of searching linear complex eigenvalues. The boundary conditions and the dynamic equation of motion are obtained by means of the Extended Principle of Hamilton for the two-span Euler-Bernoulli beam. Assuming the harmonic solution of the governing differential equations of motion, the dispersion relation is derived. To have a nontrivial solution in conjunction with the dispersion relation, the frequency equation is obtained by letting the determinant of the matrix representing the coefficients of the equations of the boundary conditions be equal to zero. The aim of this contribution is to compute the complex values of the natural frequencies from the nonlinear frequency equation by means of numerical methods for the beam supported by an intermediate spring. The real and imaginary parts of the complex eigenvalues versus the constant axial transport speed curves are depicted in order to show the linear instability. Depending on the signs of the real and imaginary parts of the complex eigenvalues, the boundaries of the instability regions were observed.

  9. Linear variable filter optimization for emergency response chemical detection and discrimination

    Science.gov (United States)

    Shen, Sylvia S.; Lewis, Paul E.

    2010-08-01

    Linear variable filter design and fabrication for LWIR is now commercially available for use in the development of remote sensing systems. The linear variable filter is attached directly to the cold shield of the focal plane array. The resulting compact spectrometer assemblies are completely contained in the Dewar system. This approach eliminates many of the wavelength calibration problems associated with current prism and grating systems and also facilitates the cost effective design and fabrication of aerial sensing systems for specific applications. This paper describes a study that was conducted with the following three objectives: 1) Determine if a multi-channel linear-variable-filter-based line scanner system can be used to discriminate a set of chemical vapors that represent a high probability of occurrence during a typical emergency response chemical incident; 2) Determine which multi-channel linear variable filter design is optimal; and 3) Determine the acceptable instrument noise equivalent spectral radiance for this application. A companion paper describes a separate study that was conducted to determine the concentration levels at which detection and discrimination can be achieved for the various chemicals based on the optimal filter design under various degrees of imperfect atmospheric correction.

  10. Non-Markovian linear response theory for quantum open systems and its applications.

    Science.gov (United States)

    Shen, H Z; Li, D X; Yi, X X

    2017-01-01

    The Kubo formula is an equation that expresses the linear response of an observable due to a time-dependent perturbation. It has been extended from closed systems to open systems in recent years under the Markovian approximation, but is barely explored for open systems in non-Markovian regimes. In this paper, we derive a formula for the linear response of an open system to a time-independent external field. This response formula is available for both Markovian and non-Markovian dynamics depending on parameters in the spectral density of the environment. As an illustration of the theory, the Hall conductance of a two-band system subjected to environments is derived and discussed. With the tight-binding model, we point out the Hall conductance changes from Markovian to non-Markovian dynamics by modulating the spectral density of the environment. Our results suggest a way to the controlling of the system response, which has potential applications for quantum statistical mechanics and condensed matter physics.

  11. On the subsystem formulation of linear-response time-dependent DFT.

    Science.gov (United States)

    Pavanello, Michele

    2013-05-28

    A new and thorough derivation of linear-response subsystem time-dependent density functional theory (TD-DFT) is presented and analyzed in detail. Two equivalent derivations are presented and naturally yield self-consistent subsystem TD-DFT equations. One reduces to the subsystem TD-DFT formalism of Neugebauer [J. Chem. Phys. 126, 134116 (2007)]. The other yields Dyson type equations involving three types of subsystem response functions: coupled, uncoupled, and Kohn-Sham. The Dyson type equations for subsystem TD-DFT are derived here for the first time. The response function formalism reveals previously hidden qualities and complications of subsystem TD-DFT compared with the regular TD-DFT of the supersystem. For example, analysis of the pole structure of the subsystem response functions shows that each function contains information about the electronic spectrum of the entire supersystem. In addition, comparison of the subsystem and supersystem response functions shows that, while the correlated response is subsystem additive, the Kohn-Sham response is not. Comparison with the non-subjective partition DFT theory shows that this non-additivity is largely an artifact introduced by the subjective nature of the density partitioning in subsystem DFT.

  12. Investigation of the longitudinal magnetic field effect on dynamic response of viscoelastic graphene sheet based on sinusoidal shear deformation theory

    Science.gov (United States)

    Arani, A. Ghorbanpour; Jalaei, M. H.

    2017-02-01

    This research aims to investigate the influence of a longitudinal magnetic field on the dynamic response of single-layered graphene sheet (SLGS) resting on viscoelastic foundation based on the nonlocal sinusoidal shear deformation theory. The present model is capable of capturing both small scale effect and transverse shear deformation effects of nanoplate, and does not require shear correction factors. The material properties of graphene sheet are assumed orthotropic viscoelastic using Kelvin-Voigt model. Utilizing Hamilton's principle governing equations of motion are derived and solved analytically. The parametric study is conducted, focusing on the remarkable effects of the magnetic field, structural damping, stiffness and damping coefficient of the foundation, nonlocal parameter, aspect ratio and length to thickness ratio on the dynamic response of the SLGS. Results indicate that the longitudinal magnetic field exerted on the SLGS decreases the amplitude of dynamic response. In addition, it is observed that the magnetic field effect on the dynamic response is more distinguished as the nonlocal parameter increases while by increasing the foundation and structural damping coefficients, this effect diminishes. The results of this study can be used in design and manufacturing of nanomechanical devices in the presence of magnetic field as a parametric controller.

  13. Investigation of the longitudinal magnetic field effect on dynamic response of viscoelastic graphene sheet based on sinusoidal shear deformation theory

    Energy Technology Data Exchange (ETDEWEB)

    Arani, A. Ghorbanpour, E-mail: aghorban@kashanu.ac.ir [Faculty of Mechanical Engineering, University of Kashan, Kashan (Iran, Islamic Republic of); Institute of Nanoscience & Nanotechnology University of Kashan, Kashan (Iran, Islamic Republic of); Jalaei, M.H. [Faculty of Mechanical Engineering, University of Kashan, Kashan (Iran, Islamic Republic of)

    2017-02-01

    This research aims to investigate the influence of a longitudinal magnetic field on the dynamic response of single-layered graphene sheet (SLGS) resting on viscoelastic foundation based on the nonlocal sinusoidal shear deformation theory. The present model is capable of capturing both small scale effect and transverse shear deformation effects of nanoplate, and does not require shear correction factors. The material properties of graphene sheet are assumed orthotropic viscoelastic using Kelvin-Voigt model. Utilizing Hamilton's principle governing equations of motion are derived and solved analytically. The parametric study is conducted, focusing on the remarkable effects of the magnetic field, structural damping, stiffness and damping coefficient of the foundation, nonlocal parameter, aspect ratio and length to thickness ratio on the dynamic response of the SLGS. Results indicate that the longitudinal magnetic field exerted on the SLGS decreases the amplitude of dynamic response. In addition, it is observed that the magnetic field effect on the dynamic response is more distinguished as the nonlocal parameter increases while by increasing the foundation and structural damping coefficients, this effect diminishes. The results of this study can be used in design and manufacturing of nanomechanical devices in the presence of magnetic field as a parametric controller.

  14. Optical response of silver clusters and their hollow shells from linear-response TDDFT

    Science.gov (United States)

    Koval, Peter; Marchesin, Federico; Foerster, Dietrich; Sánchez-Portal, Daniel

    2016-06-01

    We present a study of the optical response of compact and hollow icosahedral clusters containing up to 868 silver atoms by means of time-dependent density functional theory. We have studied the dependence on size and morphology of both the sharp plasmonic resonance at 3-4 eV (originated mainly from sp-electrons), and the less studied broader feature appearing in the 6-7 eV range (interband transitions). An analysis of the effect of structural relaxations, as well as the choice of exchange correlation functional (local density versus generalised gradient approximations) both in the ground state and optical response calculations is also presented. We have further analysed the role of the different atom layers (surface versus inner layers) and the different orbital symmetries on the absorption cross-section for energies up to 8 eV. We have also studied the dependence on the number of atom layers in hollow structures. Shells formed by a single layer of atoms show a pronounced red shift of the main plasmon resonances that, however, rapidly converge to those of the compact structures as the number of layers is increased. The methods used to obtain these results are also carefully discussed. Our methodology is based on the use of localised basis (atomic orbitals, and atom-centered and dominant-product functions), which bring several computational advantages related to their relatively small size and the sparsity of the resulting matrices. Furthermore, the use of basis sets of atomic orbitals also allows the possibility of extending some of the standard population analysis tools (e.g. Mulliken population analysis) to the realm of optical excitations. Some examples of these analyses are described in the present work.

  15. New differential equations governing the response cross-correlations of linear systems subjected to coloured loads

    Science.gov (United States)

    Falsone, G.; Settineri, D.

    2011-06-01

    A procedure for evaluating the response cross-correlation of a linear structural system subjected to the action of stationary random multi-correlated processes is presented in this work. It is based on the definition of the fourth-order differential equation governing the modal response cross-correlation and of the corresponding solution. This is expressed in terms of the corresponding fundamental matrix, whose expression is related to the fundamental matrices of the differential equations governing the modal responses. The properties of this matrix allows to define a particular unconditionally stable numerical integration approach, which is composed of two independent step-by-step procedures, a progressive one and a regressive one. The applications have shown a level of accuracy comparable to that corresponding to the numerical solution of the double convolution integral, but the presented approach is characterised by a reduced computational effort.

  16. Identifying the nonlinear mechanical behaviour of micro-speakers from their quasi-linear electrical response

    Science.gov (United States)

    Zilletti, Michele; Marker, Arthur; Elliott, Stephen John; Holland, Keith

    2017-05-01

    In this study model identification of the nonlinear dynamics of a micro-speaker is carried out by purely electrical measurements, avoiding any explicit vibration measurements. It is shown that a dynamic model of the micro-speaker, which takes into account the nonlinear damping characteristic of the device, can be identified by measuring the response between the voltage input and the current flowing into the coil. An analytical formulation of the quasi-linear model of the micro-speaker is first derived and an optimisation method is then used to identify a polynomial function which describes the mechanical damping behaviour of the micro-speaker. The analytical results of the quasi-linear model are compared with numerical results. This study potentially opens up the possibility of efficiently implementing nonlinear echo cancellers.

  17. Gamow-Teller response in deformed even and odd neutron-rich Zr and Mo isotopes

    CERN Document Server

    Sarriguren, P; Pereira, J

    2014-01-01

    Beta-decay properties of neutron-rich Zr and Mo isotopes are investigated within a microscopic theoretical approach based on the proton-neutron quasiparticle random-phase approximation. The underlying mean field is described self-consistently from deformed Skyrme Hartree-Fock calculations with pairing correlations. Residual separable particle-hole and particle-particle forces are also included in the formalism. The structural evolution in these isotopic chains including both even and odd isotopes is analyzed in terms of the equilibrium deformed shapes. Gamow-Teller strength distributions, beta-decay half-lives, and beta-delayed neutron-emission probabilities are studied, stressing their relevance to describe the path of the nucleosynthesis rapid neutron capture process.

  18. Linear Modeling and Evaluation of Controls on Flow Response in Western Post-Fire Watersheds

    Science.gov (United States)

    Saxe, S.; Hogue, T. S.; Hay, L.

    2015-12-01

    This research investigates the impact of wildfires on watershed flow regimes throughout the western United States, specifically focusing on evaluation of fire events within specified subregions and determination of the impact of climate and geophysical variables in post-fire flow response. Fire events were collected through federal and state-level databases and streamflow data were collected from U.S. Geological Survey stream gages. 263 watersheds were identified with at least 10 years of continuous pre-fire daily streamflow records and 5 years of continuous post-fire daily flow records. For each watershed, percent changes in runoff ratio (RO), annual seven day low-flows (7Q2) and annual seven day high-flows (7Q10) were calculated from pre- to post-fire. Numerous independent variables were identified for each watershed and fire event, including topographic, land cover, climate, burn severity, and soils data. The national watersheds were divided into five regions through K-clustering and a lasso linear regression model, applying the Leave-One-Out calibration method, was calculated for each region. Nash-Sutcliffe Efficiency (NSE) was used to determine the accuracy of the resulting models. The regions encompassing the United States along and west of the Rocky Mountains, excluding the coastal watersheds, produced the most accurate linear models. The Pacific coast region models produced poor and inconsistent results, indicating that the regions need to be further subdivided. Presently, RO and HF response variables appear to be more easily modeled than LF. Results of linear regression modeling showed varying importance of watershed and fire event variables, with conflicting correlation between land cover types and soil types by region. The addition of further independent variables and constriction of current variables based on correlation indicators is ongoing and should allow for more accurate linear regression modeling.

  19. Reduced Density Matrix Functional Theory (RDMFT) and Linear Response Time-Dependent RDMFT (TD-RDMFT).

    Science.gov (United States)

    Pernal, Katarzyna; Giesbertz, Klaas J H

    2016-01-01

    Recent advances in reduced density matrix functional theory (RDMFT) and linear response time-dependent reduced density matrix functional theory (TD-RDMFT) are reviewed. In particular, we present various approaches to develop approximate density matrix functionals which have been employed in RDMFT. We discuss the properties and performance of most available density matrix functionals. Progress in the development of functionals has been paralleled by formulation of novel RDMFT-based methods for predicting properties of molecular systems and solids. We give an overview of these methods. The time-dependent extension, TD-RDMFT, is a relatively new theory still awaiting practical and generally useful functionals which would work within the adiabatic approximation. In this chapter we concentrate on the formulation of TD-RDMFT response equations and various adiabatic approximations. None of the adiabatic approximations is fully satisfactory, so we also discuss a phase-dependent extension to TD-RDMFT employing the concept of phase-including-natural-spinorbitals (PINOs). We focus on applications of the linear response formulations to two-electron systems, for which the (almost) exact functional is known.

  20. MCMC Methods for Multi-Response Generalized Linear Mixed Models: The MCMCglmm R Package

    Directory of Open Access Journals (Sweden)

    Jarrod Had

    2010-02-01

    Full Text Available Generalized linear mixed models provide a flexible framework for modeling a range of data, although with non-Gaussian response variables the likelihood cannot be obtained in closed form. Markov chain Monte Carlo methods solve this problem by sampling from a series of simpler conditional distributions that can be evaluated. The R package MCMCglmm implements such an algorithm for a range of model fitting problems. More than one response variable can be analyzed simultaneously, and these variables are allowed to follow Gaussian, Poisson, multi(binominal, exponential, zero-inflated and censored distributions. A range of variance structures are permitted for the random effects, including interactions with categorical or continuous variables (i.e., random regression, and more complicated variance structures that arise through shared ancestry, either through a pedigree or through a phylogeny. Missing values are permitted in the response variable(s and data can be known up to some level of measurement error as in meta-analysis. All simu- lation is done in C/ C++ using the CSparse library for sparse linear systems.

  1. Extrinsic contribution and non-linear response in lead-free KNN-modified piezoceramics

    Energy Technology Data Exchange (ETDEWEB)

    Ochoa, D A; Garcia, J E; Perez, R; Gomis, V; Albareda, A [Department of Applied Physics, Universitat Politecnica de Catalunya, 08034 Barcelona (Spain); Rubio-Marcos, F; Fernandez, J F, E-mail: jose@fa.upc.ed [Department of Electroceramics, Instituto de Ceramica y Vidrio, CSIC, 28049 Madrid (Spain)

    2009-01-21

    Finding lead-free ceramics with good piezoelectric properties is nowadays one of the most important challenges in materials science. The (K, Na, Li)(Nb, Ta, Sb)O{sub 3} system is one of the most promising candidates as a lead-free ceramic for transducer applications and is currently the object of important research work. In this paper, (K{sub 0.44}Na{sub 0.52}Li{sub 0.04})(Nb{sub 0.86}Ta{sub 0.10}Sb{sub 0.04})O{sub 3} was prepared by a conventional ceramic processing route. For this composition, orthorhombic-to-tetragonal phase transition was observed at temperatures very close to room temperature. As a consequence, good room temperature electromechanical properties were observed, displaying good thermal stability. We show that the most important contribution to dielectric, piezoelectric and elastic response comes from extrinsic effects, as was observed in other perovskite based materials. Nonlinearities in electromechanical properties induced by high electric field or mechanical stress were studied. Non-linear dielectric response was found to be less important than for soft PZT ceramics and was analysed within the Rayleigh framework. The results reveal that the non-linear response at room temperature in this material is mainly due to the irreversible wall domain movement.

  2. Thermodynamic bounds and general properties of optimal efficiency and power in linear responses.

    Science.gov (United States)

    Jiang, Jian-Hua

    2014-10-01

    We study the optimal exergy efficiency and power for thermodynamic systems with an Onsager-type "current-force" relationship describing the linear response to external influences. We derive, in analytic forms, the maximum efficiency and optimal efficiency for maximum power for a thermodynamic machine described by a N×N symmetric Onsager matrix with arbitrary integer N. The figure of merit is expressed in terms of the largest eigenvalue of the "coupling matrix" which is solely determined by the Onsager matrix. Some simple but general relationships between the power and efficiency at the conditions for (i) maximum efficiency and (ii) optimal efficiency for maximum power are obtained. We show how the second law of thermodynamics bounds the optimal efficiency and the Onsager matrix and relate those bounds together. The maximum power theorem (Jacobi's Law) is generalized to all thermodynamic machines with a symmetric Onsager matrix in the linear-response regime. We also discuss systems with an asymmetric Onsager matrix (such as systems under magnetic field) for a particular situation and we show that the reversible limit of efficiency can be reached at finite output power. Cooperative effects are found to improve the figure of merit significantly in systems with multiply cross-correlated responses. Application to example systems demonstrates that the theory is helpful in guiding the search for high performance materials and structures in energy researches.

  3. Local and linear chemical reactivity response functions at finite temperature in density functional theory.

    Science.gov (United States)

    Franco-Pérez, Marco; Ayers, Paul W; Gázquez, José L; Vela, Alberto

    2015-12-28

    We explore the local and nonlocal response functions of the grand canonical potential density functional at nonzero temperature. In analogy to the zero-temperature treatment, local (e.g., the average electron density and the local softness) and nonlocal (e.g., the softness kernel) intrinsic response functions are defined as partial derivatives of the grand canonical potential with respect to its thermodynamic variables (i.e., the chemical potential of the electron reservoir and the external potential generated by the atomic nuclei). To define the local and nonlocal response functions of the electron density (e.g., the Fukui function, the linear density response function, and the dual descriptor), we differentiate with respect to the average electron number and the external potential. The well-known mathematical relationships between the intrinsic response functions and the electron-density responses are generalized to nonzero temperature, and we prove that in the zero-temperature limit, our results recover well-known identities from the density functional theory of chemical reactivity. Specific working equations and numerical results are provided for the 3-state ensemble model.

  4. Local and linear chemical reactivity response functions at finite temperature in density functional theory

    Energy Technology Data Exchange (ETDEWEB)

    Franco-Pérez, Marco, E-mail: francopj@mcmaster.ca, E-mail: ayers@mcmaster.ca, E-mail: jlgm@xanum.uam.mx, E-mail: avela@cinvestav.mx [Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1 (Canada); Departamento de Química, Universidad Autónoma Metropolitana-Iztapalapa, Av. San Rafael Atlixco 186, México, D.F. 09340 (Mexico); Ayers, Paul W., E-mail: francopj@mcmaster.ca, E-mail: ayers@mcmaster.ca, E-mail: jlgm@xanum.uam.mx, E-mail: avela@cinvestav.mx [Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1 (Canada); Gázquez, José L., E-mail: francopj@mcmaster.ca, E-mail: ayers@mcmaster.ca, E-mail: jlgm@xanum.uam.mx, E-mail: avela@cinvestav.mx [Departamento de Química, Universidad Autónoma Metropolitana-Iztapalapa, Av. San Rafael Atlixco 186, México, D.F. 09340 (Mexico); Vela, Alberto, E-mail: francopj@mcmaster.ca, E-mail: ayers@mcmaster.ca, E-mail: jlgm@xanum.uam.mx, E-mail: avela@cinvestav.mx [Departamento de Química, Centro de Investigación y de Estudios Avanzados (Cinvestav), Av. Instituto Politécnico Nacional 2508, México, D.F. 07360 (Mexico)

    2015-12-28

    We explore the local and nonlocal response functions of the grand canonical potential density functional at nonzero temperature. In analogy to the zero-temperature treatment, local (e.g., the average electron density and the local softness) and nonlocal (e.g., the softness kernel) intrinsic response functions are defined as partial derivatives of the grand canonical potential with respect to its thermodynamic variables (i.e., the chemical potential of the electron reservoir and the external potential generated by the atomic nuclei). To define the local and nonlocal response functions of the electron density (e.g., the Fukui function, the linear density response function, and the dual descriptor), we differentiate with respect to the average electron number and the external potential. The well-known mathematical relationships between the intrinsic response functions and the electron-density responses are generalized to nonzero temperature, and we prove that in the zero-temperature limit, our results recover well-known identities from the density functional theory of chemical reactivity. Specific working equations and numerical results are provided for the 3-state ensemble model.

  5. Numerical Modeling of Particle-Fluid Mixtures in a Subglacial Setting: Granular Deformation and Hydrological Flow Response

    Science.gov (United States)

    Damsgaard, A.; Egholm, D. L.; Piotrowski, J. A.; Tulaczyk, S. M.; Larsen, N. K.

    2014-12-01

    The coupled mechanical response of ice, water and sediment may control the flow of warm-based glaciers residing on deformable sediment. This is most clearly expressed by the fast flowing ice streams in Greenland and Antarctica, where low levels of basal friction are thought to support the high flow rates. These ice streams are of particular interest since they are large constituents of the polar ice sheet mass balance. The study of these ice streams and their future impact on the ice sheets necessitates a deeper understanding of their basal dynamics, including the rheology of water-saturated sediment. We present the methodology and first results of a coupled numerical model for computational experiments on granular-fluid mixtures under dynamic conditions similar to those in subglacial settings. The granular phase is simulated on a per-particle basis by the soft body discrete element method. The fluid phase is handled as a continuum by solving the incompressible Navier-Stokes equations. The particle and fluid phases are coupled by mass conservation and momentum exchanges. The hydraulic diffusivity and permeability is compared to previous laboratory studies on tills. We demonstrate how the onset and halt of granular deformation is an efficient mechanism to create fluid pressure fluctuations due to local porosity changes. These pressure anomalies are driving transient hydraulic flows, and they influence directly the rheology of granular-fluid mixtures. Our results highlight the nonlinear nature of water saturated granular deformation, and demonstrate how the mechanical behaviour of granular materials may include both brittle and viscous components depending on the rates of deformation and the hydrological properties.

  6. Linear-response time-dependent density-functional theory with pairing fields.

    Science.gov (United States)

    Peng, Degao; van Aggelen, Helen; Yang, Yang; Yang, Weitao

    2014-05-14

    Recent development in particle-particle random phase approximation (pp-RPA) broadens the perspective on ground state correlation energies [H. van Aggelen, Y. Yang, and W. Yang, Phys. Rev. A 88, 030501 (2013), Y. Yang, H. van Aggelen, S. N. Steinmann, D. Peng, and W. Yang, J. Chem. Phys. 139, 174110 (2013); D. Peng, S. N. Steinmann, H. van Aggelen, and W. Yang, J. Chem. Phys. 139, 104112 (2013)] and N ± 2 excitation energies [Y. Yang, H. van Aggelen, and W. Yang, J. Chem. Phys. 139, 224105 (2013)]. So far Hartree-Fock and approximated density-functional orbitals have been utilized to evaluate the pp-RPA equation. In this paper, to further explore the fundamentals and the potential use of pairing matrix dependent functionals, we present the linear-response time-dependent density-functional theory with pairing fields with both adiabatic and frequency-dependent kernels. This theory is related to the density-functional theory and time-dependent density-functional theory for superconductors, but is applied to normal non-superconducting systems for our purpose. Due to the lack of the proof of the one-to-one mapping between the pairing matrix and the pairing field for time-dependent systems, the linear-response theory is established based on the representability assumption of the pairing matrix. The linear response theory justifies the use of approximated density-functionals in the pp-RPA equation. This work sets the fundamentals for future density-functional development to enhance the description of ground state correlation energies and N ± 2 excitation energies.

  7. A Revolute Joint With Linear Load-Displacement Response for Precision Deployable Structures

    Science.gov (United States)

    Lake, Mark S.; Warren, Peter A.; Peterson, Lee D.

    1996-01-01

    NASA Langley Research center is developing key structures and mechanisms technologies for micron-accuracy, in-space deployment of future space instruments. Achieving micron-accuracy deployment requires significant advancements in deployment mechanism design such as the revolute joint presented herein. The joint presented herein exhibits a load-cycling response that is essentially linear with less than two percent hysteresis, and the joint rotates with less than one in.-oz. of resistance. A prototype reflector metering truss incorporating the joint exhibits only a few microns of kinematic error under repeated deployment and impulse loading. No other mechanically deployable structure found in literature has been demonstrated to be this kinematically accurate.

  8. Linear theory of the response of Na mixing ratio to gravity waves

    Institute of Scientific and Technical Information of China (English)

    XU Jiyao; JI Qiao; WU Mingliang

    2003-01-01

    The influence of gravity waves on the sodium layer is studied by using a linear photochemical-dynamical coupling gravity wave model. The model includes the background photochemistry and the photochemical reactions in the sodium layer. The amplitude and phase difference of the response of sodium mixing ratio to gravity waves are calculated. The results indicate that the lower part of sodium layer is the most sensitive region responding to gravity waves. The perturbation of sodium mixing ratio is in phase with temperature in the lower part of the layer. However, it is out of phase with temperature fluctuation in the upper part.

  9. Linear response calculation using the canonical-basis TDHFB with a schematic pairing functional

    CERN Document Server

    Ebata, Shuichiro; Yabana, Kazuhiro

    2010-01-01

    A canonical-basis formulation of the time-dependent Hartree-Fock-Bogoliubov (TDHFB) theory is obtained with an approximation that the pair potential is assumed to be diagonal in the time-dependent canonical basis. The canonical-basis formulation significantly reduces the computational cost. We apply the method to linear-response calculations for even-even nuclei. E1 strength distributions for proton-rich Mg isotopes are systematically calculated. The calculation suggests strong Landau damping of giant dipole resonance for drip-line nuclei.

  10. Variable Selection for Semiparametric Varying-Coefficient Partially Linear Models with Missing Response at Random

    Institute of Scientific and Technical Information of China (English)

    Pei Xin ZHAO; Liu Gen XUE

    2011-01-01

    In this paper,we present a variable selection procedure by combining basis function approximations with penalized estimating equations for semiparametric varying-coefficient partially linear models with missing response at random.The proposed procedure simultaneously selects significant variables in parametric components and nonparametric components.With appropriate selection of the tuning parameters,we establish the consistency of the variable selection procedure and the convergence rate of the regularized estimators.A simulation study is undertaken to assess the finite sample performance of the proposed variable selection procedure.

  11. Linear Psoriasis

    Directory of Open Access Journals (Sweden)

    Agarwalla Arun

    2001-01-01

    Full Text Available Linear psoriasis, inflammatory linear varrucous epidermal naevus (ILVEN. Lichen straitus, linear lichen planus and invasion of epidermal naevi by psoriasis have clinical and histopathological overlap. We report two young male patients of true linear psoriasis without classical lesions elsewhere which were proved histopathologically. Seasonal variation and good response to topical antipsoriatic treatment supported the diagnosis.

  12. Comparisons of linear and nonlinear plasma response models for non-axisymmetric perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Turnbull, A. D.; Ferraro, N. M.; Lao, L. L.; Lanctot, M. J. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Izzo, V. A. [University of California-San Diego, 9500 Gilman Dr., La Jolla, California 92093-0417 (United States); Lazarus, E. A.; Hirshman, S. P. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, Tennessee 37831 (United States); Park, J.-K.; Lazerson, S.; Reiman, A. [Princeton Plasma Physics Laboratory, P.O. Box 451, Princeton, New Jersey 08543-0451 (United States); Cooper, W. A. [Association Euratom-Confederation Suisse, Centre de Recherches en Physique des Plasmas, Ecole Polytechnique Federale de Lausanne, Lausanne (Switzerland); Liu, Y. Q. [Culham Centre for Fusion Energy, Culham Science Centre, Abingdon, Oxfordshire, OX14 3DB (United Kingdom); Turco, F. [Columbia University, 116th St and Broadway, New York, New York 10027 (United States)

    2013-05-15

    With the installation of non-axisymmetric coil systems on major tokamaks for the purpose of studying the prospects of ELM-free operation, understanding the plasma response to the applied fields is a crucial issue. Application of different response models, using standard tools, to DIII-D discharges with applied non-axisymmetric fields from internal coils, is shown to yield qualitatively different results. The plasma response can be treated as an initial value problem, following the system dynamically from an initial unperturbed state, or from a nearby perturbed equilibrium approach, and using both linear and nonlinear models [A. D. Turnbull, Nucl. Fusion 52, 054016 (2012)]. Criteria are discussed under which each of the approaches can yield a valid response. In the DIII-D cases studied, these criteria show a breakdown in the linear theory despite the small 10{sup −3} relative magnitude of the applied magnetic field perturbations in this case. For nonlinear dynamical evolution simulations to reach a saturated nonlinear steady state, appropriate damping mechanisms need to be provided for each normal mode comprising the response. Other issues arise in the technical construction of perturbed flux surfaces from a displacement and from the presence of near nullspace normal modes. For the nearby equilibrium approach, in the absence of a full 3D equilibrium reconstruction with a controlled comparison, constraints relating the 2D system profiles to the final profiles in the 3D system also need to be imposed to assure accessibility. The magnetic helicity profile has been proposed as an appropriate input to a 3D equilibrium calculation and tests of this show the anticipated qualitative behavior.

  13. The neuronal response at extended timescales: a linearized spiking input-output relation

    Directory of Open Access Journals (Sweden)

    Daniel eSoudry

    2014-04-01

    Full Text Available Many biological systems are modulated by unknown slow processes. This can severely hinder analysis - especially in excitable neurons, which are highly non-linear and stochastic systems. We show the analysis simplifies considerably if the input matches the sparse spiky nature of the output. In this case, a linearized spiking Input-Output (I/O relation can be derived semi-analytically, relating input spike trains to output spikes based on known biophysical properties. Using this I/O relation we obtain closed-form expressions for all second order statistics (input - internal state - output correlations and spectra, construct optimal linear estimators for the neuronal response and internal state and perform parameter identification. These results are guaranteed to hold, for a general stochastic biophysical neuron model, with only a few assumptions (mainly, timescale separation. We numerically test the resulting expressions for various models, and show that they hold well, even in cases where our assumptions fail to hold. In a companion paper we demonstrate how this approach enables us to fit a biophysical neuron model so it reproduces experimentally observed temporal firing statistics on days-long experiments.

  14. The neuronal response at extended timescales: a linearized spiking input-output relation.

    Science.gov (United States)

    Soudry, Daniel; Meir, Ron

    2014-01-01

    Many biological systems are modulated by unknown slow processes. This can severely hinder analysis - especially in excitable neurons, which are highly non-linear and stochastic systems. We show the analysis simplifies considerably if the input matches the sparse "spiky" nature of the output. In this case, a linearized spiking Input-Output (I/O) relation can be derived semi-analytically, relating input spike trains to output spikes based on known biophysical properties. Using this I/O relation we obtain closed-form expressions for all second order statistics (input - internal state - output correlations and spectra), construct optimal linear estimators for the neuronal response and internal state and perform parameter identification. These results are guaranteed to hold, for a general stochastic biophysical neuron model, with only a few assumptions (mainly, timescale separation). We numerically test the resulting expressions for various models, and show that they hold well, even in cases where our assumptions fail to hold. In a companion paper we demonstrate how this approach enables us to fit a biophysical neuron model so it reproduces experimentally observed temporal firing statistics on days-long experiments.

  15. Linearization of EBT3 film dose response and virtual film dosimetry for SBRT quality assurance

    Science.gov (United States)

    Cai, M.; Archibald-Heeren, B.; Wang, Y.; Metcalfe, P.

    2017-01-01

    EBT3 film offers high spatial resolution and low energy dependence, making it a suitable choice for quality assurance where high dose gradients are present, such as the case for SBRT. This work presents a simple method to adjust scanner settings so that dose response becomes linear. This linearity eliminates the need to obtain a calibration curve and associated uncertainties in curve fitting. Relative dosimetry can be performed after dose normalization to a reference point. Linearity is also a more robust condition than calibration curve with respect to scanner warm-up conditions, resulting in reduced uncertainty in dose measurement. An in-house developed program reads the film scan and a 2D dose map then constructs both to virtual films using grayscale values. Film intensity value was normalized to dose at reference point. Relative dosimetry was performed by comparing the two resulting images. Patient specific quality assurance was conducted for two SBRT cases. In both plans more than 95% gamma function points passed the gamma criteria of 2%/3mm.

  16. Multiple linear and principal component regressions for modelling ecotoxicity bioassay response.

    Science.gov (United States)

    Gomes, Ana I; Pires, José C M; Figueiredo, Sónia A; Boaventura, Rui A R

    2014-01-01

    The ecotoxicological response of the living organisms in an aquatic system depends on the physical, chemical and bacteriological variables, as well as the interactions between them. An important challenge to scientists is to understand the interaction and behaviour of factors involved in a multidimensional process such as the ecotoxicological response. With this aim, multiple linear regression (MLR) and principal component regression were applied to the ecotoxicity bioassay response of Chlorella vulgaris and Vibrio fischeri in water collected at seven sites of Leça river during five monitoring campaigns (February, May, June, August and September of 2006). The river water characterization included the analysis of 22 physicochemical and 3 microbiological parameters. The model that best fitted the data was MLR, which shows: (i) a negative correlation with dissolved organic carbon, zinc and manganese, and a positive one with turbidity and arsenic, regarding C. vulgaris toxic response; (ii) a negative correlation with conductivity and turbidity and a positive one with phosphorus, hardness, iron, mercury, arsenic and faecal coliforms, concerning V. fischeri toxic response. This integrated assessment may allow the evaluation of the effect of future pollution abatement measures over the water quality of Leça River.

  17. Linearized Unsteady Aerodynamic Analysis of the Acoustic Response to Wake/Blade-Row Interaction

    Science.gov (United States)

    Verdon, Joseph M.; Huff, Dennis L. (Technical Monitor)

    2001-01-01

    The three-dimensional, linearized Euler analysis, LINFLUX, is being developed to provide a comprehensive and efficient unsteady aerodynamic scheme for predicting the aeroacoustic and aeroelastic responses of axial-flow turbomachinery blading. LINFLUX couples a near-field, implicit, wave-split, finite-volume solution to far-field acoustic eigensolutions, to predict the aerodynamic responses of a blade row to prescribed structural and aerodynamic excitations. It is applied herein to predict the acoustic responses of a fan exit guide vane (FEGV) to rotor wake excitations. The intent is to demonstrate and assess the LINFLUX analysis via application to realistic wake/blade-row interactions. Numerical results are given for the unsteady pressure responses of the FEGV, including the modal pressure responses at inlet and exit. In addition, predictions for the modal and total acoustic power levels at the FEGV exit are compared with measurements. The present results indicate that the LINFLUX analysis should be useful in the aeroacoustic design process, and for understanding the three-dimensional flow physics relevant to blade-row noise generation and propagation.

  18. Non-linear modeling of the plasma response to RMPs in ASDEX Upgrade

    CERN Document Server

    Orain, F; Viezzer, E; Dunne, M; Becoulet, M; Cahyna, P; Huijsmans, G T A; Morales, J; Willensdorfer, M; Suttrop, W; Kirk, A; Pamela, S; Strumberger, E; Guenter, S; Lessig, A

    2016-01-01

    The plasma response to Resonant Magnetic Perturbations (RMPs) in ASDEX Upgrade is modeled with the non-linear resistive MHD code JOREK, using input profiles that match those of the experiments as closely as possible. The RMP configuration for which Edge Localized Modes are best mitigated in experiments is related to the largest edge kink response observed near the X-point in modeling. On the edge resonant surfaces q = m=n, the coupling between the m + 2 kink component and the m resonant component is found to induce the amplification of the resonant magnetic perturbation. The ergodicity and the 3D-displacement near the X-point induced by the resonant ampli?cation can only partly explain the density pumpout observed in experiments.

  19. Non-linear intensification of Sahel rainfall as a possible dynamic response to future warming

    Directory of Open Access Journals (Sweden)

    J. Schewe

    2017-07-01

    Full Text Available Projections of the response of Sahel rainfall to future global warming diverge significantly. Meanwhile, paleoclimatic records suggest that Sahel rainfall is capable of abrupt transitions in response to gradual forcing. Here we present climate modeling evidence for the possibility of an abrupt intensification of Sahel rainfall under future climate change. Analyzing 30 coupled global climate model simulations, we identify seven models where central Sahel rainfall increases by 40 to 300 % over the 21st century, owing to a northward expansion of the West African monsoon domain. Rainfall in these models is non-linearly related to sea surface temperature (SST in the tropical Atlantic and Mediterranean moisture source regions, intensifying abruptly beyond a certain SST warming level. We argue that this behavior is consistent with a self-amplifying dynamic–thermodynamical feedback, implying that the gradual increase in oceanic moisture availability under warming could trigger a sudden intensification of monsoon rainfall far inland of today's core monsoon region.

  20. Non-linear intensification of Sahel rainfall as a possible dynamic response to future warming

    Science.gov (United States)

    Schewe, Jacob; Levermann, Anders

    2017-07-01

    Projections of the response of Sahel rainfall to future global warming diverge significantly. Meanwhile, paleoclimatic records suggest that Sahel rainfall is capable of abrupt transitions in response to gradual forcing. Here we present climate modeling evidence for the possibility of an abrupt intensification of Sahel rainfall under future climate change. Analyzing 30 coupled global climate model simulations, we identify seven models where central Sahel rainfall increases by 40 to 300 % over the 21st century, owing to a northward expansion of the West African monsoon domain. Rainfall in these models is non-linearly related to sea surface temperature (SST) in the tropical Atlantic and Mediterranean moisture source regions, intensifying abruptly beyond a certain SST warming level. We argue that this behavior is consistent with a self-amplifying dynamic-thermodynamical feedback, implying that the gradual increase in oceanic moisture availability under warming could trigger a sudden intensification of monsoon rainfall far inland of today's core monsoon region.

  1. Optical nonlinear response of a single nonlinear dielectric layer sandwiched between two linear dielectric structures

    Energy Technology Data Exchange (ETDEWEB)

    Lidorikis, E. [Ames Laboratory--USDOE and Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011 (United States); Busch, K. [Ames Laboratory--USDOE and Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011 (United States)]|[Instituet fuer Theorie der Kondensierten Materie, Universitaet Karlsruhe, D-76128, Karlsruhe (Germany); Li, Q. [Ames Laboratory--USDOE and Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011 (United States); Chan, C.T. [Ames Laboratory--USDOE and Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011 (United States)]|[Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong (China); Soukoulis, C.M. [Ames Laboratory--USDOE and Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011 (United States)

    1997-12-01

    We consider the general problem of electromagnetic wave propagation through a one-dimensional system consisting of a nonlinear medium sandwiched between two linear structures. Special emphasis is given to systems where the latter comprise Bragg reflectors. We obtain an exact expression for the nonlinear response of such dielectric superlattices when the nonlinear impurity is very thin, or in the {delta}-function limit. We find that both the switching-up and switching-down intensities of the bistable response can be made very low, when the frequency of the incident wave matches that of the impurity mode of the structure. Numerical results for a nonlinear layer of finite width display qualitatively similar behavior, thus confirming the usefulness of the simpler {delta}-function model. In addition, an analytical solution for the resonance states of an infinitely extended finite-width superlattice with a finite-width nonlinear impurity is presented. {copyright} {ital 1997} {ital The American Physical Society}

  2. On the Boundary between Nonlinear Jump Phenomenon and Linear Response of Hypoid Gear Dynamics

    Directory of Open Access Journals (Sweden)

    Jun Wang

    2011-01-01

    Full Text Available A nonlinear time-varying (NLTV dynamic model of a hypoid gear pair system with time-dependent mesh point, line-of-action vector, mesh stiffness, mesh damping, and backlash nonlinearity is formulated to analyze the transitional phase between nonlinear jump phenomenon and linear response. It is found that the classical jump discontinuity will occur if the dynamic mesh force exceeds the mean value of tooth mesh force. On the other hand, the propensity for the gear response to jump disappears when the dynamic mesh force is lower than the mean mesh force. Furthermore, the dynamic analysis is able to distinguish the specific tooth impact types from analyzing the behaviors of the dynamic mesh force. The proposed theory is general and also applicable to high-speed spur, helical and spiral bevel gears even though those types of gears are not the primary focus of this paper.

  3. Non-linear modeling of the plasma response to RMPs in ASDEX Upgrade

    Science.gov (United States)

    Orain, F.; Hölzl, M.; Viezzer, E.; Dunne, M.; Bécoulet, M.; Cahyna, P.; Huijsmans, G. T. A.; Morales, J.; Willensdorfer, M.; Suttrop, W.; Kirk, A.; Pamela, S.; Günter, S.; Lackner, K.; Strumberger, E.; Lessig, A.; the ASDEX Upgrade Team; the EUROfusion MST1 Team

    2017-02-01

    The plasma response to resonant magnetic perturbations (RMPs) in ASDEX Upgrade is modeled with the non-linear resistive MHD code JOREK, using input profiles that match those of the experiments as closely as possible. The RMP configuration for which edge localized modes are best mitigated in experiments is related to the largest edge kink response observed near the X-point in modeling. On the edge resonant surfaces q  =  m/n, the coupling between the kink component (m  >  nq) and the m resonant component is found to induce the amplification of the resonant magnetic perturbation. The ergodicity and the 3D-displacement near the X-point induced by the resonant amplification can only partly explain the density pumpout observed in experiments.

  4. Linear response, fluctuation-dissipation, and finite-system-size effects in superdiffusion.

    Science.gov (United States)

    Godec, Aljaž; Metzler, Ralf

    2013-07-01

    Lévy walks (LWs) are a popular stochastic tool to model anomalous diffusion and have recently been used to describe a variety of phenomena. We study the linear response behavior of this generic model of superdiffusive LWs in finite systems to an external force field under both stationary and nonstationary conditions. These finite-size LWs are based on power-law waiting time distributions with a finite-time regularization at τ(c), such that the physical requirements are met to apply linear response theory and derive the power spectrum with the correct short frequency limit, without the introduction of artificial cutoffs. We obtain the generalized Einstein relation for both ensemble and time averages over the entire process time and determine the turnover to normal Brownian motion when the full system is explored. In particular, we obtain an exact expression for the long time diffusion constant as a function of the scaling exponent of the waiting time density and the characteristic time scale τ(c).

  5. Effects of resistivity on linear plasma responses to resonant magnetic perturbations in tokamak plasmas

    Science.gov (United States)

    Kim, Juhyung; Kim, S. S.; Jhang, Hogun

    2016-09-01

    Numerical studies are made of the effects of resistivity on linear plasma responses to resonant magnetic perturbations (RMPs) in tokamaks based on a reduced magnetohydrodynamic model. From a local two-field model, it is suggested that the ratio of the poloidal electron advection to the resistivity diffusion rate α m can be a figure of merit parameter in linear RMP penetration physics. The shielding efficiency is governed by α m , and when α m ≳ 1 , RMPs are effectively shielded. Global simulations using a four-field model [Hazeltine and Meiss, Phys. Rep. 121, 1 (1985)] show that there exists an effective threshold of the perpendicular electron flow ( Ve , ⊥ c ) beyond which RMPs cannot penetrate. Resistivity is found to determine Ve , ⊥ c which increases as resistivity becomes higher, making RMP penetration easier. At low resistivity, small Ve , ⊥ c renders the RMP penetration sensitive to ion collisionality and the change in q95. The kink response is observed to be closely related to the residual level of RMPs at rational surfaces and can be also strongly affected by resistivity.

  6. Linear-response reflection coefficient of the recorder air-jet amplifier

    CERN Document Server

    Price, John C; McKinnon, Daniel D

    2015-01-01

    In a duct-flute such as the recorder, steady-state oscillations are controlled by only two parameters, the blowing pressure and the frequency of the acoustic resonator. As in most feedback oscillators, the oscillation amplitude is determined by gain-saturation of the amplifier, and cannot be controlled independently of other parameters unless the feedback loop is opened. We attempt to open the loop by replacing the recorder body with a waveguide reflectometer: a section of transmission line with microphones, a signal source, and an absorbing termination. We measure the reflection coefficient of the head versus blowing pressure and acoustic frequency, focusing on the simplest case of linear response where saturation does not occur. Our results depend strongly on whether the mean flow from the air-jet into the transmission line is blocked or not. When it is not blocked, the amplifier displays edge-tone oscillations and linear response measurements are thwarted. When it is blocked, the air-jet is deflected somew...

  7. Linear response theory for the density matrix renormalization group: efficient algorithms for strongly correlated excited states.

    Science.gov (United States)

    Nakatani, Naoki; Wouters, Sebastian; Van Neck, Dimitri; Chan, Garnet Kin-Lic

    2014-01-14

    Linear response theory for the density matrix renormalization group (DMRG-LRT) was first presented in terms of the DMRG renormalization projectors [J. J. Dorando, J. Hachmann, and G. K.-L. Chan, J. Chem. Phys. 130, 184111 (2009)]. Later, with an understanding of the manifold structure of the matrix product state (MPS) ansatz, which lies at the basis of the DMRG algorithm, a way was found to construct the linear response space for general choices of the MPS gauge in terms of the tangent space vectors [J. Haegeman, J. I. Cirac, T. J. Osborne, I. Pižorn, H. Verschelde, and F. Verstraete, Phys. Rev. Lett. 107, 070601 (2011)]. These two developments led to the formulation of the Tamm-Dancoff and random phase approximations (TDA and RPA) for MPS. This work describes how these LRTs may be efficiently implemented through minor modifications of the DMRG sweep algorithm, at a computational cost which scales the same as the ground-state DMRG algorithm. In fact, the mixed canonical MPS form implicit to the DMRG sweep is essential for efficient implementation of the RPA, due to the structure of the second-order tangent space. We present ab initio DMRG-TDA results for excited states of polyenes, the water molecule, and a [2Fe-2S] iron-sulfur cluster.

  8. Lead-lag relationships between stock and market risk within linear response theory

    Science.gov (United States)

    Borysov, Stanislav; Balatsky, Alexander

    2015-03-01

    We study historical correlations and lead-lag relationships between individual stock risks (standard deviation of daily stock returns) and market risk (standard deviation of daily returns of a market-representative portfolio) in the US stock market. We consider the cross-correlation functions averaged over stocks, using historical stock prices from the Standard & Poor's 500 index for 1994-2013. The observed historical dynamics suggests that the dependence between the risks was almost linear during the US stock market downturn of 2002 and after the US housing bubble in 2007, remaining at that level until 2013. Moreover, the averaged cross-correlation function often had an asymmetric shape with respect to zero lag in the periods of high correlation. We develop the analysis by the application of the linear response formalism to study underlying causal relations. The calculated response functions suggest the presence of characteristic regimes near financial crashes, when individual stock risks affect market risk and vice versa. This work was supported by VR 621-2012-2983.

  9. Linear response theory for the density matrix renormalization group: Efficient algorithms for strongly correlated excited states

    Science.gov (United States)

    Nakatani, Naoki; Wouters, Sebastian; Van Neck, Dimitri; Chan, Garnet Kin-Lic

    2014-01-01

    Linear response theory for the density matrix renormalization group (DMRG-LRT) was first presented in terms of the DMRG renormalization projectors [J. J. Dorando, J. Hachmann, and G. K.-L. Chan, J. Chem. Phys. 130, 184111 (2009)]. Later, with an understanding of the manifold structure of the matrix product state (MPS) ansatz, which lies at the basis of the DMRG algorithm, a way was found to construct the linear response space for general choices of the MPS gauge in terms of the tangent space vectors [J. Haegeman, J. I. Cirac, T. J. Osborne, I. Pižorn, H. Verschelde, and F. Verstraete, Phys. Rev. Lett. 107, 070601 (2011)]. These two developments led to the formulation of the Tamm-Dancoff and random phase approximations (TDA and RPA) for MPS. This work describes how these LRTs may be efficiently implemented through minor modifications of the DMRG sweep algorithm, at a computational cost which scales the same as the ground-state DMRG algorithm. In fact, the mixed canonical MPS form implicit to the DMRG sweep is essential for efficient implementation of the RPA, due to the structure of the second-order tangent space. We present ab initio DMRG-TDA results for excited states of polyenes, the water molecule, and a [2Fe-2S] iron-sulfur cluster.

  10. A Capacitor-Free, Fast Transient Response Linear Voltage Regulator In a 180nm CMOS

    DEFF Research Database (Denmark)

    Deleuran, Alexander N.; Lindbjerg, Nicklas; Pedersen, Martin K.

    2015-01-01

    A 1.8 V capacitor-free linear regulator with fast transient response based on a new topology with a fast and slow regulation loop is presented. The design has been laid out and simulated in a 0.18 µm CMOS process. The design has a low component count and is tailored for system-on-chip integration....... A current step load from 0-50 mA with a rise time of 1 µs results in an undershoot in the output voltage of 140 mV for a period of 39 ns. The regulator sources up to 50 mA current load.......A 1.8 V capacitor-free linear regulator with fast transient response based on a new topology with a fast and slow regulation loop is presented. The design has been laid out and simulated in a 0.18 µm CMOS process. The design has a low component count and is tailored for system-on-chip integration...

  11. Practical methods for dealing with 'not applicable' item responses in the AMC Linear Disability Score project

    Directory of Open Access Journals (Sweden)

    Zwinderman Aeilko H

    2004-06-01

    Full Text Available Abstract Background Whenever questionnaires are used to collect data on constructs, such as functional status or health related quality of life, it is unlikely that all respondents will respond to all items. This paper examines ways of dealing with responses in a 'not applicable' category to items included in the AMC Linear Disability Score (ALDS project item bank. Methods The data examined in this paper come from the responses of 392 respondents to 32 items and form part of the calibration sample for the ALDS item bank. The data are analysed using the one-parameter logistic item response theory model. The four practical strategies for dealing with this type of response are: cold deck imputation; hot deck imputation; treating the missing responses as if these items had never been offered to those individual patients; and using a model which takes account of the 'tendency to respond to items'. Results The item and respondent population parameter estimates were very similar for the strategies involving hot deck imputation; treating the missing responses as if these items had never been offered to those individual patients; and using a model which takes account of the 'tendency to respond to items'. The estimates obtained using the cold deck imputation method were substantially different. Conclusions The cold deck imputation method was not considered suitable for use in the ALDS item bank. The other three methods described can be usefully implemented in the ALDS item bank, depending on the purpose of the data analysis to be carried out. These three methods may be useful for other data sets examining similar constructs, when item response theory based methods are used.

  12. Practical methods for dealing with 'not applicable' item responses in the AMC Linear Disability Score project

    Science.gov (United States)

    Holman, Rebecca; Glas, Cees AW; Lindeboom, Robert; Zwinderman, Aeilko H; de Haan, Rob J

    2004-01-01

    Background Whenever questionnaires are used to collect data on constructs, such as functional status or health related quality of life, it is unlikely that all respondents will respond to all items. This paper examines ways of dealing with responses in a 'not applicable' category to items included in the AMC Linear Disability Score (ALDS) project item bank. Methods The data examined in this paper come from the responses of 392 respondents to 32 items and form part of the calibration sample for the ALDS item bank. The data are analysed using the one-parameter logistic item response theory model. The four practical strategies for dealing with this type of response are: cold deck imputation; hot deck imputation; treating the missing responses as if these items had never been offered to those individual patients; and using a model which takes account of the 'tendency to respond to items'. Results The item and respondent population parameter estimates were very similar for the strategies involving hot deck imputation; treating the missing responses as if these items had never been offered to those individual patients; and using a model which takes account of the 'tendency to respond to items'. The estimates obtained using the cold deck imputation method were substantially different. Conclusions The cold deck imputation method was not considered suitable for use in the ALDS item bank. The other three methods described can be usefully implemented in the ALDS item bank, depending on the purpose of the data analysis to be carried out. These three methods may be useful for other data sets examining similar constructs, when item response theory based methods are used. PMID:15200681

  13. Linear, Star, and Comb Oxidation-Responsive Polymers: Effect of Branching Degree and Topology on Aggregation and Responsiveness.

    Science.gov (United States)

    d'Arcy, Richard; Gennari, Arianna; Donno, Roberto; Tirelli, Nicola

    2016-12-01

    Families of amphiphilic oxidation-responsive polymers (poly(ethylene glycol)-polysulfides) with different architectures (linear, 4, 6, and 8-armed stars and 10, 15, and 20-armed combs) and compositions (variable ethylene sulfide/propylene sulfide ratio) are prepared. In water, all the polymers assemble in spherical micelles, with critical micellar concentrations <0.01 mg mL(-1) for all the branched polymers. Triple-detection gel permeation chromatography (GPC) and asymmetric field flow fractionation (AFFF) with dynamic and static light scattering detection, respectively, show an increasing compaction of the polymeric coil and a strong reduction of the aggregation number with increasing degree of branching. The key finding of this study is that the kinetics of the oxidative response sharply depend on the branching; in particular, it is highlighted that the degree of branching influences the lag time before a response can be observed rather than the speed of the response itself, a phenomenon that is attributed to a branching-dependent solubility of the oxidant in the polysulfide matrix.

  14. OREGANO_VE: a new parallelised 3D solver for the general (non-)linear Maxwell visco-elastic problem: validation and application to the calculation of surface deformation in the earthquake cycle

    Science.gov (United States)

    Yamasaki, Tadashi; Houseman, Gregory; Hamling, Ian; Postek, Elek

    2010-05-01

    We have developed a new parallelized 3-D numerical code, OREGANO_VE, for the solution of the general visco-elastic problem in a rectangular block domain. The mechanical equilibrium equation is solved using the finite element method for a (non-)linear Maxwell visco-elastic rheology. Time-dependent displacement and/or traction boundary conditions can be applied. Matrix assembly is based on a tetrahedral element defined by 4 vertex nodes and 6 nodes located at the midpoints of the edges, and within which displacement is described by a quadratic interpolation function. For evaluating viscoelastic relaxation, an explicit time-stepping algorithm (Zienkiewicz and Cormeau, Int. J. Num. Meth. Eng., 8, 821-845, 1974) is employed. We test the accurate implementation of the OREGANO_VE by comparing numerical and analytic (or semi-analytic half-space) solutions to different problems in a range of applications: (1) equilibration of stress in a constant density layer after gravity is switched on at t = 0 tests the implementation of spatially variable viscosity and non-Newtonian viscosity; (2) displacement of the welded interface between two blocks of differing viscosity tests the implementation of viscosity discontinuities, (3) displacement of the upper surface of a layer under applied normal load tests the implementation of time-dependent surface tractions (4) visco-elastic response to dyke intrusion (compared with the solution in a half-space) tests the implementation of all aspects. In each case, the accuracy of the code is validated subject to use of a sufficiently small time step, providing assurance that the OREGANO_VE code can be applied to a range of visco-elastic relaxation processes in three dimensions, including post-seismic deformation and post-glacial uplift. The OREGANO_VE code includes a capability for representation of prescribed fault slip on an internal fault. The surface displacement associated with large earthquakes can be detected by some geodetic observations

  15. A New Method of Studying Quantitatively the Non-Linear Elasticity Deformation Rock Volumetric Strain%一种定量研究非线弹性岩石体积应变新方法

    Institute of Scientific and Technical Information of China (English)

    李莲明; 李治平; 车艳

    2011-01-01

    When the rock is deformed by pressure decreasing in the formation, it is difficult to study the non-linear elasticity deformation rock volumetric strain. According to the power relationship between the non-elastic deformation rock elastic modelling quantity and effective pressure, this paper establishes the theoretic expressions between rock volumetric strain and effective pressure under the surface experiment conditions and the formation conditions, proposese a new method of the “Trial Calculation & Iteration”used to study the non-linear elasticity deformation rock volumetric strain quantitatively, calculates the a and b values of the rock non-linear elasticity deformation constants by means of the experiment databetween the non-linear elasticity rock volumetric strain and the effective pressure, and forecastes the non-linear elasticity deformation rock volumetric strain quantitatively. The application of this method indicates that the relative errors between the predictive values of the non-linear rock volumetric strain, rock porosity under the surface experiment conditions & rock porosity of the formation pressure decrease and the experiment values or the predictive values using experiment data of them should be less than or equal to 7.39%,0.80% & 3.92% and preferable consistance, and that it is possible to convert from the experimental data of the surface conditions to the data of reservoir conditions. This method provides an effective way to calculate the non-linear elasticity deformation rock volumetric strain quantitatively.%砂岩气藏地层压力下降岩石发生非线弹性变形时,定量研究非线弹性岩石体积应变的大小是个难点.由非线弹性岩石弹性模量与有效压力满足的乘幂关系,推导了地面实验和地层条件岩石体积应变理论关系,提出了一种定量研究岩石体积应变的试算迭代法,并结合岩石变形实验岩石体积应变与有效压力变化数据,求取了岩

  16. Exactly isochoric deformations of soft solids

    Science.gov (United States)

    Biggins, John S.; Wei, Z.; Mahadevan, L.

    2014-12-01

    Many materials of contemporary interest, such as gels, biological tissues and elastomers, are easily deformed but essentially incompressible. Traditional linear theory of elasticity implements incompressibility only to first order and thus permits some volume changes, which become problematically large even at very small strains. Using a mixed coordinate transformation originally due to Gauss, we enforce the constraint of isochoric deformations exactly to develop a linear theory with perfect volume conservation that remains valid until strains become geometrically large. We demonstrate the utility of this approach by calculating the response of an infinite soft isochoric solid to a point force that leads to a nonlinear generalization of the Kelvin solution. Our approach naturally generalizes to a range of problems involving deformations of soft solids and interfaces in two-dimensional and axisymmetric geometries, which we exemplify by determining the solution to a distributed load that mimics muscular contraction within the bulk of a soft solid.

  17. A Fresh Look at Linear Ordinary Differential Equations with Constant Coefficients. Revisiting the Impulsive Response Method Using Factorization

    Science.gov (United States)

    Camporesi, Roberto

    2016-01-01

    We present an approach to the impulsive response method for solving linear constant-coefficient ordinary differential equations of any order based on the factorization of the differential operator. The approach is elementary, we only assume a basic knowledge of calculus and linear algebra. In particular, we avoid the use of distribution theory, as…

  18. The vestibular evoked response to linear, alternating, acceleration pulses without acoustic masking as a parameter of vestibular function

    NARCIS (Netherlands)

    Oei, MLYM; Segenhout, JM; Wit, HP; Albers, FWJ

    In this study, short latency vestibular evoked potentials (VsEPs) were recorded in five guinea pigs in response to alternating linear acceleration pulses with and without acoustic masking. A steel bolt was implanted in the skull and coupled to a shaker. Linear acceleration pulses (n = 400) in

  19. The vestibular evoked response to linear, alternating, acceleration pulses without acoustic masking as a parameter of vestibular function

    NARCIS (Netherlands)

    Oei, MLYM; Segenhout, JM; Wit, HP; Albers, FWJ

    2001-01-01

    In this study, short latency vestibular evoked potentials (VsEPs) were recorded in five guinea pigs in response to alternating linear acceleration pulses with and without acoustic masking. A steel bolt was implanted in the skull and coupled to a shaker. Linear acceleration pulses (n = 400) in upward

  20. Circular Path and Linear Momentum (CPLM Method for Seismic Response Analysis of Vehicles

    Directory of Open Access Journals (Sweden)

    Rishi Ram Parajuli

    2016-07-01

    Full Text Available We propose a circular path and linear momentum method for the seismic response analysis of vehicles. This method considers the momentum induced by earthquake excitation and applies the concept of centripetal force acting laterally on the vehicle in addition to longitudinal forces. This method is valid for vehicles at rest as well as those moving at a range of speeds. The vertical responses are calculated using a quarter vehicle model. We also calculate the translational motion of the vehicle using a model with six degrees of freedom. Three vehicle types (car, bus, and truck were used in the analysis. We compared the result with analysis of the response of a shaking vehicle from video footage recorded during the Gorkha earthquake. We used the input ground motion from 10 large earthquakes of moment magnitudes 6.7 to 9.0. All three components of the ground motion were used in the analysis. Vehicles at rest and moving at various speeds were analysed. The lateral and longitudinal responses of the vehicles were calculated for different vehicle speeds ranging from 0 to 30.0 m/s, PGA excitations and orientations of the vehicle.

  1. Fully relativistic description of spin-orbit torques by means of linear response theory

    Science.gov (United States)

    Wimmer, S.; Chadova, K.; Seemann, M.; Ködderitzsch, D.; Ebert, H.

    2016-08-01

    Symmetry and magnitude of spin-orbit torques (SOT), i.e., current-induced torques on the magnetization of systems lacking inversion symmetry, are investigated in a fully relativistic linear response framework based on the Kubo formalism. By applying all space-time symmetry operations contained in the magnetic point group of a solid to the relevant response coefficient, the torkance expressed as torque-current correlation function, restrictions to the shape of the direct and inverse response tensors are obtained. These are shown to apply to the corresponding thermal analogs as well, namely the direct and inverse thermal SOT in response to a temperature gradient or heat current. Using an implementation of the Kubo-Bastin formula for the torkance into a first-principles multiple-scattering Green function framework and accounting for disorder effects via the so-called coherent potential approximation, all contributions to the SOT in pure systems, dilute as well as concentrated alloys can be treated on equal footing. This way, material specific values for all torkance tensor elements in the fcc (111) trilayer alloy system Pt| FexCo1 -x|Cu are obtained over a wide concentration range and discussed in comparison to results for electrical and spin conductivity, as well as to previous work—in particular concerning symmetry with respect to magnetization reversal and the nature of the various contributions.

  2. Exchange Energy Density Functionals that reproduce the Linear Response Function of the Free Electron Gas

    Science.gov (United States)

    García-Aldea, David; Alvarellos, J. E.

    2009-03-01

    We present several nonlocal exchange energy density functionals that reproduce the linear response function of the free electron gas. These nonlocal functionals are constructed following a similar procedure used previously for nonlocal kinetic energy density functionals by Chac'on-Alvarellos-Tarazona, Garc'ia-Gonz'alez et al., Wang-Govind-Carter and Garc'ia-Aldea-Alvarellos. The exchange response function is not known but we have used the approximate response function developed by Utsumi and Ichimaru, even we must remark that the same ansatz can be used to reproduce any other response function with the same scaling properties. We have developed two families of new nonlocal functionals: one is constructed with a mathematical structure based on the LDA approximation -- the Dirac functional for the exchange - and for the second one the structure of the second order gradient expansion approximation is took as a model. The functionals are constructed is such a way that they can be used in localized systems (using real space calculations) and in extended systems (using the momentum space, and achieving a quasilinear scaling with the system size if a constant reference electron density is defined).

  3. Alanine aminotransferase and risk of the metabolic syndrome: a linear dose-response relationship.

    Directory of Open Access Journals (Sweden)

    Setor K Kunutsor

    Full Text Available BACKGROUND: Elevated baseline circulating alanine aminotransferase (ALT level has been demonstrated to be associated with an increased risk of the metabolic syndrome (MetS, but the nature of the dose-response relationship is uncertain. METHODS: We performed a systematic review and meta-analysis of published prospective cohort studies to characterize in detail the nature of the dose-response relationship between baseline ALT level and risk of incident MetS in the general population. Relevant studies were identified in a literature search of MEDLINE, EMBASE, and Web of Science up to December 2013. Prospective studies in which investigators reported relative risks (RRs of MetS for 3 or more categories of ALT levels were eligible. A potential nonlinear relationship between ALT levels and MetS was examined using restricted cubic splines. RESULTS: Of the 489 studies reviewed, relevant data were available on 29,815 non-overlapping participants comprising 2,125 incident MetS events from five prospective cohort studies. There was evidence of a linear association (P for nonlinearity=0.38 between ALT level and risk of MetS, characterised by a graded increase in MetS risk at ALT levels 6-40 U/L. The risk of MetS increased by 14% for every 5 U/L increment in circulating ALT level (95% CI: 12-17%. Evidence was lacking of heterogeneity and publication bias among the contributing studies. CONCLUSIONS: Baseline ALT level is associated with risk of the MetS in a linear dose-response manner. Studies are needed to determine whether the association represents a causal relationship.

  4. The dose-response relationship for cardiovascular disease is not necessarily linear.

    Science.gov (United States)

    Schneider, Uwe; Ernst, Marina; Hartmann, Matthias

    2017-04-27

    The probability for a complication after radiotherapy is usually a function of dose and volume in the organ or tissue of interest. In most epidemiological studies the risk for a complication is stratified in terms of dose, but not irradiated volume. We show that the obtained risk cannot generally be applied to radiotherapy patients.The epidemiological data of Darby et al. (N Engl J Med 368:2527, 2013) who found a linear relationship between the excess relative risk of major coronary events as function of mean heart dose in patients treated with tangential breast irradiation are analyzed. We have used the relative seriality model for a partly irradiated heart ("a lot to a little") which models radiation therapy using two tangential fields. The relative seriality model was then used to predict NTCP of cardiovascular disease for a homogenously irradiated heart ("a little to a lot"). The relative seriality model was fitted to the data of Darby et al. (N Engl J Med 368:2527, 2013) for tangential breast irradiation. For the situation "a little to a lot" it was found that the dose-response relationship is sigmoidal and contradicts the findings of Darby et al. (N Engl J Med 368:2527, 2013). It was shown in this work that epidemiological studies which predict a linear dose-response relationship for cardiovascular disease can be reproduced by bio-physical models for normal tissue complication. For irradiation situations which were not included in the epidemiological studies, e.g. a homogenous irradiation of the heart ("a little to a lot") the dose-response curve can be different. This could have consequences whether or not IMRT should be used for treating breast cancer. We believe that the results of epidemiological studies should not be generally used to predict normal tissue complications. It is better to use such data to optimize bio-physical models which can then be applied (with caution) to general treatment situations.

  5. Cancer risk assessment: Optimizing human health through linear dose-response models.

    Science.gov (United States)

    Calabrese, Edward J; Shamoun, Dima Yazji; Hanekamp, Jaap C

    2015-07-01

    This paper proposes that generic cancer risk assessments be based on the integration of the Linear Non-Threshold (LNT) and hormetic dose-responses since optimal hormetic beneficial responses are estimated to occur at the dose associated with a 10(-4) risk level based on the use of a LNT model as applied to animal cancer studies. The adoption of the 10(-4) risk estimate provides a theoretical and practical integration of two competing risk assessment models whose predictions cannot be validated in human population studies or with standard chronic animal bioassay data. This model-integration reveals both substantial protection of the population from cancer effects (i.e. functional utility of the LNT model) while offering the possibility of significant reductions in cancer incidence should the hormetic dose-response model predictions be correct. The dose yielding the 10(-4) cancer risk therefore yields the optimized toxicologically based "regulatory sweet spot". Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Indoor calibration of Sky Quality Meters: Linearity, spectral responsivity and uncertainty analysis

    Science.gov (United States)

    Pravettoni, M.; Strepparava, D.; Cereghetti, N.; Klett, S.; Andretta, M.; Steiger, M.

    2016-09-01

    The indoor calibration of brightness sensors requires extremely low values of irradiance in the most accurate and reproducible way. In this work the testing equipment of an ISO 17025 accredited laboratory for electrical testing, qualification and type approval of solar photovoltaic modules was modified in order to test the linearity of the instruments from few mW/cm2 down to fractions of nW/cm2, corresponding to levels of simulated brightness from 6 to 19 mag/arcsec2. Sixteen Sky Quality Meter (SQM) produced by Unihedron, a Canadian manufacturer, were tested, also assessing the impact of the ageing of their protective glasses on the calibration coefficients and the drift of the instruments. The instruments are in operation on measurement points and observatories at different sites and altitudes in Southern Switzerland, within the framework of OASI, the Environmental Observatory of Southern Switzerland. The authors present the results of the calibration campaign: linearity; brightness calibration, with and without protective glasses; transmittance measurement of the glasses; and spectral responsivity of the devices. A detailed uncertainty analysis is also provided, according to the ISO 17025 standard.

  7. Non-Linear Dynamic Response of a Spur Gear Pair: Modelling and Experimental Comparisons

    Science.gov (United States)

    PARKER, R. G.; VIJAYAKAR, S. M.; IMAJO, T.

    2000-10-01

    The dynamic response of a spur gear pair is investigated using a finite element/contact mechanics model that offers significant advantages for dynamic gear analyses. The gear pair is analyzed across a wide range of operating speeds and torques. Comparisons are made to other researchers' published experiments that reveal complex non-linear phenomena. The non-linearity source is contact loss of the meshing teeth, which, in contrast to the prevailing understanding, occurs even for large torques despite the use of high-precision gears. A primary feature of the modelling is that dynamic mesh forces are calculated using a detailed contact analysis at each time step as the gears roll through the mesh; there is no need to externally specify the excitation in the form of time-varying mesh stiffness, static transmission error input, or the like. A semi-analytical model near the tooth surface is matched to a finite element solution away from the tooth surface, and the computational efficiency that results permits dynamic analysis. Two-single-degree-of-freedom models are also studied. While one gives encouragingly good results, the other, which appears to have better mesh stiffness modelling, gives poor comparisons with experiments. The results indicate the sensitivity of such models to the Fourier spectrum of the changing mesh stiffness.

  8. Non-linear response of infinite periodic solids to homogenous electric fields and collective atomic displacements

    Science.gov (United States)

    Ghosez, Philippe

    2006-03-01

    The non-linear response of infinite periodic solids to homogenous electric fields and cooperative atomic displacements will be discussed in the framework of density functional perturbation theory. The approach is based on the “2n + 1” theorem applied to an electric field dependent energy functional. We will focus on the non-linear optical susceptibilities, Raman scattering efficiencies and electrooptic coefficients. Different formulations of third-order energy derivatives will be examined and their convergence with respect to the k-point sampling will be discussed. The method will be applied to conventional semiconductors and to ferroelectric oxides. In the latter case, we will also describe how the first- principles results can be combined to an effective Hamiltonian approach in order to provide access to the temperature dependence of the optical properties. This work was done in collabration with M. Veithen and X. Gonze and was supported by the VolkwagenStiftung, FNRS-Belgium and the FAME-NoE.

  9. Ab initio calculation of the Gilbert damping parameter via the linear response formalism.

    Science.gov (United States)

    Ebert, H; Mankovsky, S; Ködderitzsch, D; Kelly, P J

    2011-08-05

    A Kubo-Greenwood-like equation for the Gilbert damping parameter α is presented that is based on the linear response formalism. Its implementation using the fully relativistic Korringa-Kohn-Rostoker band structure method in combination with coherent potential approximation alloy theory allows it to be applied to a wide range of situations. This is demonstrated with results obtained for the bcc alloy system Fe(1-x)Co(x) as well as for a series of alloys of Permalloy with 5d transition metals. To account for the thermal displacements of atoms as a scattering mechanism, an alloy-analogy model is introduced. The corresponding calculations for Ni correctly describe the rapid change of α when small amounts of substitutional Cu are introduced.

  10. Derivation of spin-orbit couplings in collinear linear-response TDDFT: A rigorous formulation

    Science.gov (United States)

    Franco de Carvalho, Felipe; Curchod, Basile F. E.; Penfold, Thomas J.; Tavernelli, Ivano

    2014-04-01

    Using an approach based upon a set of auxiliary many-electron wavefunctions we present a rigorous derivation of spin-orbit coupling (SOC) within the framework of linear-response time-dependent density functional theory (LR-TDDFT). Our method is based on a perturbative correction of the non-relativistic collinear TDDFT equations using a Breit-Pauli spin-orbit Hamiltonian. The derivation, which is performed within both the Casida and Sternheimer formulations of LR-TDDFT, is valid for any basis set. The requirement of spin noncollinearity for the treatment of spin-flip transitions is also discussed and a possible alternative solution for the description of these transitions in the collinear case is also proposed. Our results are validated by computing the SOC matrix elements between singlet and triplet states of two molecules, formaldehyde and acetone. In both cases, we find excellent agreement with benchmark calculations performed with a high level correlated wavefunction method.

  11. Derivation of spin-orbit couplings in collinear linear-response TDDFT: A rigorous formulation

    Energy Technology Data Exchange (ETDEWEB)

    Franco de Carvalho, Felipe; Curchod, Basile F. E.; Tavernelli, Ivano, E-mail: ivano.tavernelli@epfl.ch [Laboratory of Computational Chemistry and Biochemistry, Ecole Polytechnique Fédérale de Lausanne, CH-1015 (Switzerland); Penfold, Thomas J. [SwissFEL, Paul Scherrer Inst, CH-5232 Villigen (Switzerland)

    2014-04-14

    Using an approach based upon a set of auxiliary many-electron wavefunctions we present a rigorous derivation of spin-orbit coupling (SOC) within the framework of linear-response time-dependent density functional theory (LR-TDDFT). Our method is based on a perturbative correction of the non-relativistic collinear TDDFT equations using a Breit-Pauli spin-orbit Hamiltonian. The derivation, which is performed within both the Casida and Sternheimer formulations of LR-TDDFT, is valid for any basis set. The requirement of spin noncollinearity for the treatment of spin-flip transitions is also discussed and a possible alternative solution for the description of these transitions in the collinear case is also proposed. Our results are validated by computing the SOC matrix elements between singlet and triplet states of two molecules, formaldehyde and acetone. In both cases, we find excellent agreement with benchmark calculations performed with a high level correlated wavefunction method.

  12. Global hybrids from the semiclassical atom theory satisfying the local density linear response

    CERN Document Server

    Fabiano, E; Cortona, P; Della Sala, F

    2015-01-01

    We propose global hybrid approximations of the exchange-correlation (XC) energy functional which reproduce well the modified fourth-order gradient expansion of the exchange energy in the semiclassical limit of many-electron neutral atoms and recover the full local density approximation (LDA) linear response. These XC functionals represent the hybrid versions of the APBE functional [Phys. Rev. Lett. 106, 186406, (2011)] yet employing an additional correlation functional which uses the localization concept of the correlation energy density to improve the compatibility with the Hartree-Fock exchange as well as the coupling-constant-resolved XC potential energy. Broad energetical and structural testings, including thermochemistry and geometry, transition metal complexes, non-covalent interactions, gold clusters and small gold-molecule interfaces, as well as an analysis of the hybrid parameters, show that our construction is quite robust. In particular, our testing shows that the resulting hybrid, including 20\\% o...

  13. Exciton Absorption Spectra by Linear Response Methods: Application to Conjugated Polymers.

    Science.gov (United States)

    Mosquera, Martín A; Jackson, Nicholas E; Fauvell, Thomas J; Kelley, Matthew S; Chen, Lin X; Schatz, George C; Ratner, Mark A

    2017-03-15

    The theoretical description of the time-evolution of excitons requires, as an initial step, the calculation of their spectra, which has been inaccessible to most users due to the high computational scaling of conventional algorithms and accuracy issues caused by common density functionals. Previously (J. Chem. Phys. 2016, 144, 204105), we developed a simple method that resolves these issues. Our scheme is based on a two-step calculation in which a linear-response TDDFT calculation is used to generate orbitals perturbed by the excitonic state, and then a second linear-response TDDFT calculation is used to determine the spectrum of excitations relative to the excitonic state. Herein, we apply this theory to study near-infrared absorption spectra of excitons in oligomers of the ubiquitous conjugated polymers poly(3-hexylthiophene) (P3HT), poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV), and poly(benzodithiophene-thieno[3,4-b]thiophene) (PTB7). For P3HT and MEH-PPV oligomers, the calculated intense absorption bands converge at the longest wavelengths for 10 monomer units, and show strong consistency with experimental measurements. The calculations confirm that the exciton spectral features in MEH-PPV overlap with those of the bipolaron formation. In addition, our calculations identify the exciton absorption bands in transient absorption spectra measured by our group for oligomers (1, 2, and 3 units) of PTB7. For all of the cases studied, we report the dominant orbital excitations contributing to the optically active excited state-excited state transitions, and suggest a simple rule to identify absorption peaks at the longest wavelengths. We suggest our methodology could be considered for further developments in theoretical transient spectroscopy to include nonadiabatic effects, coherences, and to describe the formation of species such as charge-transfer states and polaron pairs.

  14. Quantum Kramers model: Corrections to the linear response theory for continuous bath spectrum

    Science.gov (United States)

    Rips, Ilya

    2017-01-01

    Decay of the metastable state is analyzed within the quantum Kramers model in the weak-to-intermediate dissipation regime. The decay kinetics in this regime is determined by energy exchange between the unstable mode and the stable modes of thermal bath. In our previous paper [Phys. Rev. A 42, 4427 (1990), 10.1103/PhysRevA.42.4427], Grabert's perturbative approach to well dynamics in the case of the discrete bath [Phys. Rev. Lett. 61, 1683 (1988), 10.1103/PhysRevLett.61.1683] has been extended to account for the second order terms in the classical equations of motion (EOM) for the stable modes. Account of the secular terms reduces EOM for the stable modes to those of the forced oscillator with the time-dependent frequency (TDF oscillator). Analytic expression for the characteristic function of energy loss of the unstable mode has been derived in terms of the generating function of the transition probabilities for the quantum forced TDF oscillator. In this paper, the approach is further developed and applied to the case of the continuous frequency spectrum of the bath. The spectral density functions of the bath of stable modes are expressed in terms of the dissipative properties (the friction function) of the original bath. They simplify considerably for the one-dimensional systems, when the density of phonon states is constant. Explicit expressions for the fourth order corrections to the linear response theory result for the characteristic function of the energy loss and its cumulants are obtained for the particular case of the cubic potential with Ohmic (Markovian) dissipation. The range of validity of the perturbative approach in this case is determined (γ /ωbrate for the quantum and for the classical Kramers models. Results for the classical escape rate are in very good agreement with the numerical simulations for high barriers. The results can serve as an additional proof of the robustness and accuracy of the linear response theory.

  15. Testing For The Linearity of Responses To Multiple Anthropogenic Climate Forcings

    Science.gov (United States)

    Forest, C. E.; Stone, P. H.; Sokolov, A. P.

    To test whether climate forcings are additive, we compare climate model simulations in which anthropogenic forcings are applied individually and in combination. Tests are performed with different values for climate system properties (climate sensitivity and rate of heat uptake by the deep ocean) as well as for different strengths of the net aerosol forcing, thereby testing for the dependence of linearity on these properties. The MIT 2D Land-Ocean Climate Model used in this study consists of a zonally aver- aged statistical-dynamical atmospheric model coupled to a mixed-layer Q-flux ocean model, with heat anomalies diffused into the deep ocean. Following our previous stud- ies, the anthropogenic forcings are the changes in concentrations of greenhouse gases (1860-1995), sulfate aerosol (1860-1995), and stratospheric and tropospheric ozone (1979-1995). The sulfate aerosol forcing is applied as a surface albedo change. For an aerosol forcing of -1.0 W/m2 and an effective ocean diffusitivity of 2.5 cm2/s, the nonlinearity of the response of global-mean surface temperatures to the combined forcing shows a strong dependence on climate sensitivity. The fractional change in decadal averages ([(TG + TS + TO) - TGSO]/TGSO) for the 1986-1995 period compared to pre-industrial times are 0.43, 0.90, and 1.08 with climate sensitiv- ities of 3.0, 4.5, and 6.2 C, respectively. The values of TGSO for these three cases o are 0.52, 0.62, and 0.76 C. The dependence of linearity on climate system properties, o the role of climate system feedbacks, and the implications for the detection of climate system's response to individual forcings will be presented. Details of the model and forcings can be found at http://web.mit.edu/globalchange/www/.

  16. Influence of the localized initial plastic deformation on the effective thermomechanical response of metal-matrix composites

    Energy Technology Data Exchange (ETDEWEB)

    Roatta, A.; Turner, P.A.; Bertinetti, M.A.; Bolmaro, R.E.

    1999-11-01

    A generalized Eshelby model, allowing interaction among reinforcing particles under a Mori-Tanaka-like scheme, is presented. Different inclusion aspect ratios are studied in the elastic and incipient elastoplastic regime for a model SiC-Al composite. The solution of the field equations is obtained via an explicit algorithm that yields the interaction field in terms of the stress and strain variables. The particles and fibers are taken as purely elastic, and the matrix is regarded as elastic-perfectly plastic. Coefficients of thermal expansion (CTE) are calculated both under the assumption of purely elastic response and at the onset of plastic localized deformation. The simulated stress-strain curves show the influence of interaction stresses on macroscopic yield stress for different inclusion aspect ratios, with no consideration of matrix hardening. The model allows a good simulation of the thermomechanical behavior of composite materials and contributes to the understanding of the elastoplastic transition in stress-strain curves. It can also simply explain some of the most distinctive features of the mechanical behavior of composites. The model presents the possibility of controlling many input variables and geometries and simultaneously considering three-dimensional deformation of interacting inclusion-reinforced materials with low computational effort. Comparisons to experimental CTE and residual stresses are provided.

  17. Calibration of the linear response range of x-ray imaging plates and their reader based on image grayscale values

    Science.gov (United States)

    Ren, Kuan; Xu, Tao; Zheng, Jianhua; Dong, Jianjun; Wei, Minxi; Li, Chaoguang; Cao, Zhurong; Du, Huabing; Yan, Ji; Yang, Guohong; Yi, Rongqing; Zhang, Jiyan; Huang, Tianxuan; Liu, Shenye; Wang, Feng; Yang, Zhiwen; Li, Jin; Chen, Yaohua; Lan, Ke; Ren, Guoli; Liu, Jie; Ding, Yongkun; Jiang, Shaoen

    2017-08-01

    X-ray imaging plates are one of the most important X-ray imaging detectors and are widely used in inertial-confinement fusion experiments. However, their linear response range, which is the foundation of their quantitative data analysis, has not been sufficiently deeply investigated. In this work, we develop an X-ray fluorescer calibration system and carefully explore the linear response range of X-ray imaging plates. For the first time, nearly the entire grayscale range of the X-ray imaging plate linear response—7819-64 879 in the range of 0-65 535—has been observed. Further, we discuss the uncertainties involved in the calibration process. This work demonstrates the excellent linear response qualities of X-ray imaging plates and provides a significant foundation for expanding their quantitative applied range.

  18. Is the pain visual analogue scale linear and responsive to change? An exploration using Rasch analysis.

    Directory of Open Access Journals (Sweden)

    Paula Kersten

    Full Text Available OBJECTIVES: Pain visual analogue scales (VAS are commonly used in clinical trials and are often treated as an interval level scale without evidence that this is appropriate. This paper examines the internal construct validity and responsiveness of the pain VAS using Rasch analysis. METHODS: Patients (n = 221, mean age 67, 58% female with chronic stable joint pain (hip 40% or knee 60% of mechanical origin waiting for joint replacement were included. Pain was scored on seven daily VASs. Rasch analysis was used to examine fit to the Rasch model. Responsiveness (Standardized Response Means, SRM was examined on the raw ordinal data and the interval data generated from the Rasch analysis. RESULTS: Baseline pain VAS scores fitted the Rasch model, although 15 aberrant cases impacted on unidimensionality. There was some local dependency between items but this did not significantly affect the person estimates of pain. Daily pain (item difficulty was stable, suggesting that single measures can be used. Overall, the SRMs derived from ordinal data overestimated the true responsiveness by 59%. Changes over time at the lower and higher end of the scale were represented by large jumps in interval equivalent data points; in the middle of the scale the reverse was seen. CONCLUSIONS: The pain VAS is a valid tool for measuring pain at one point in time. However, the pain VAS does not behave linearly and SRMs vary along the trait of pain. Consequently, Minimum Clinically Important Differences using raw data, or change scores in general, are invalid as these will either under- or overestimate true change; raw pain VAS data should not be used as a primary outcome measure or to inform parametric-based Randomised Controlled Trial power calculations in research studies; and Rasch analysis should be used to convert ordinal data to interval data prior to data interpretation.

  19. Thermal Cycling and Isothermal Deformation Response of Polycrystalline NiTi: Simulations vs. Experiment

    Science.gov (United States)

    Manchiraju, Sivom; Gaydosh, Darrell; Benafan, Othmane; Noebe, Ronald; Vaidyanathan, Raj; Anderson, Peter M.

    2011-01-01

    A recent microstructure-based FEM model that couples crystal-based plasticity, the B2 MB190 phase transformation and anisotropic elasticity at the grain scale is calibrated to recent data for polycrystalline NiTi (49.9 at.% Ni). Inputs include anisotropic elastic properties, texture and differential scanning calorimetry data, as well as a subset of recent isothermal deformation and load-biased thermal cycling data. The model is assessed against additional experimental data. Several experimental trends are captured - in particular, the transformation strain during thermal cycling monotonically increases and reaches a peak with increasing bias stress. This is achieved, in part, by modifying the martensite hardening matrix proposed by Patoor et al. [Patoor E, Eberhardt A, Berveiller M. J Phys IV 1996;6:277]. Some experimental trends are underestimated - in particular, the ratcheting of macrostrain during thermal cycling. This may reflect a model limitation that transformation-plasticity coupling is captured on a coarse (grain) scale but not on a fine (martensitic plate) scale.

  20. On spurious detection of linear response and misuse of the fluctuation-dissipation theorem in finite time series

    Science.gov (United States)

    Gottwald, Georg A.; Wormell, J. P.; Wouters, Jeroen

    2016-09-01

    Using a sensitive statistical test we determine whether or not one can detect the breakdown of linear response given observations of deterministic dynamical systems. A goodness-of-fit statistics is developed for a linear statistical model of the observations, based on results for central limit theorems for deterministic dynamical systems, and used to detect linear response breakdown. We apply the method to discrete maps which do not obey linear response and show that the successful detection of breakdown depends on the length of the time series, the magnitude of the perturbation and on the choice of the observable. We find that in order to reliably reject the assumption of linear response for typical observables sufficiently large data sets are needed. Even for simple systems such as the logistic map, one needs of the order of 106 observations to reliably detect the breakdown with a confidence level of 95 %; if less observations are available one may be falsely led to conclude that linear response theory is valid. The amount of data required is larger the smaller the applied perturbation. For judiciously chosen observables the necessary amount of data can be drastically reduced, but requires detailed a priori knowledge about the invariant measure which is typically not available for complex dynamical systems. Furthermore we explore the use of the fluctuation-dissipation theorem (FDT) in cases with limited data length or coarse-graining of observations. The FDT, if applied naively to a system without linear response, is shown to be very sensitive to the details of the sampling method, resulting in erroneous predictions of the response.

  1. On the linear response and scattering of an interacting molecule-metal system

    Energy Technology Data Exchange (ETDEWEB)

    Masiello, David J.; Schatz, George C.

    2010-01-01

    A many-body Green’s function approach to the microscopic theory of plasmon-enhanced spectroscopy is presented within the context of localized surface-plasmon resonancespectroscopy and applied to investigate the coupling between quantum-molecular and classical-plasmonic resonances in monolayer-coated silver nanoparticles. Electronic propagators or Green’s functions, accounting for the repeated polarizationinteraction between a single molecule and its image in a nearby nanoscale metal, are explicitly computed and used to construct the linear-response properties of the combined molecule-metal system to an external electromagnetic perturbation. Shifting and finite lifetime of states appear rigorously and automatically within our approach and reveal an intricate coupling between molecule and metal not fully described by previous theories. Self-consistent incorporation of this quantum-molecular response into the continuum-electromagnetic scattering of the molecule-metal target is exploited to compute the localized surface-plasmon resonance wavelength shift with respect to the bare metal from first principles.

  2. Modelling the non-linear response of Spanish electricity demand to temperature variations

    Energy Technology Data Exchange (ETDEWEB)

    Moral-Carcedo, J. [Universidad Autonoma de Madrid (Spain). Dpto. Analisis Economico; Vicens-Otero, J. [Universidad de Madrid (Spain). Dpto. Economia Aplicada

    2005-05-01

    The demand for electricity is a key variable because its links to economic activity and development; however, the electricity consumption also depends on other non-economic variables, notably the weather. The aim of this study is to analyse the effect of temperatures on the variability of the Spanish daily electricity demand, and especially to characterise the non-linearity of the response of demand to variations in temperature. In this article, we explore the ability of Smooth Transition (STR), Threshold Regression (TR), and Switching Regressions (SR) models, to handle both aspects. As we conclude, the use of LSTR approach offers two main advantages. First, it captures adequately the smooth response of electricity demand to temperature variations in intermediate ranges of temperatures. Second, it provides a method to analyse the validity of temperature thresholds used to build the ''cooling degree days'' (CDD) and ''heating degree days'' (HDD) variables traditionally employed in the literature. (author)

  3. Polarizable embedding with a multiconfiguration short-range density functional theory linear response method

    Energy Technology Data Exchange (ETDEWEB)

    Hedegård, Erik Donovan, E-mail: erik.hedegard@phys.chem.ethz.ch [Laboratorium fur Physikalische Chemie, ETH Zürich, Vladimir Prelog Weg 2, CH-8093 Zürich (Switzerland); Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense (Denmark); Olsen, Jógvan Magnus Haugaard [Laboratory of Computational Chemistry and Biochemistry, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne (Switzerland); Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense (Denmark); Knecht, Stefan [Laboratorium fur Physikalische Chemie, ETH Zürich, Vladimir Prelog Weg 2, CH-8093 Zürich (Switzerland); Kongsted, Jacob, E-mail: kongsted@sdu.dk; Jensen, Hans Jørgen Aagaard, E-mail: hjj@sdu.dk [Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense (Denmark)

    2015-03-21

    We present here the coupling of a polarizable embedding (PE) model to the recently developed multiconfiguration short-range density functional theory method (MC-srDFT), which can treat multiconfigurational systems with a simultaneous account for dynamical and static correlation effects. PE-MC-srDFT is designed to combine efficient treatment of complicated electronic structures with inclusion of effects from the surrounding environment. The environmental effects encompass classical electrostatic interactions as well as polarization of both the quantum region and the environment. Using response theory, molecular properties such as excitation energies and oscillator strengths can be obtained. The PE-MC-srDFT method and the additional terms required for linear response have been implemented in a development version of DALTON. To benchmark the PE-MC-srDFT approach against the literature data, we have investigated the low-lying electronic excitations of acetone and uracil, both immersed in water solution. The PE-MC-srDFT results are consistent and accurate, both in terms of the calculated solvent shift and, unlike regular PE-MCSCF, also with respect to the individual absolute excitation energies. To demonstrate the capabilities of PE-MC-srDFT, we also investigated the retinylidene Schiff base chromophore embedded in the channelrhodopsin protein. While using a much more compact reference wave function in terms of active space, our PE-MC-srDFT approach yields excitation energies comparable in quality to CASSCF/CASPT2 benchmarks.

  4. Librational response of a deformed 3-layer Titan perturbed by non-keplerian orbit and atmospheric couplings

    CERN Document Server

    Richard, Andy; Charnay, Benjamin

    2014-01-01

    The analyses of Titan's gravity field obtained by Cassini space mission suggest the presence of an internal ocean beneath its icy surface. The characterization of the geophysical parameters of the icy shell and the ocean is important to constrain the evolution models of Titan. The knowledge of the librations, that are periodic oscillations around a uniform rotational motion, can bring piece of information on the interior parameters. The objective of this paper is to study the librational response in longitude from an analytical approach for Titan composed of a deep atmosphere, an elastic icy shell, an internal ocean, and an elastic rocky core perturbed by the gravitational interactions with Saturn. We start from the librational equations developed for a rigid satellite in synchronous spin-orbit resonance. We introduce explicitly the atmospheric torque acting on the surface computed from the Titan IPSL GCM (Institut Pierre Simon Laplace General Circulation Model) and the periodic deformations of elastic solid ...

  5. Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents

    Science.gov (United States)

    Klapacz, Joanna; Pottenger, Lynn H.; Engelward, Bevin P.; Heinen, Christopher D.; Johnson, George E.; Clewell, Rebecca A.; Carmichael, Paul L.; Adeleye, Yeyejide; Andersen, Melvin E.

    2016-01-01

    From a risk assessment perspective, DNA-reactive agents are conventionally assumed to have genotoxic risks at all exposure levels, thus applying a linear extrapolation for low-dose responses. New approaches discussed here, including more diverse and sensitive methods for assessing DNA damage and DNA repair, strongly support the existence of measurable regions where genotoxic responses with increasing doses are insignificant relative to control. Model monofunctional alkylating agents have in vitro and in vivo datasets amenable to determination of points of departure (PoDs) for genotoxic effects. A session at the 2013 Society of Toxicology meeting provided an opportunity to survey the progress in understanding the biological basis of empirically-observed PoDs for DNA alkylating agents. Together with the literature published since, this review discusses cellular pathways activated by endogenous and exogenous alkylation DNA damage. Cells have evolved conserved processes that monitor and counteract a spontaneous steady-state level of DNA damage. The ubiquitous network of DNA repair pathways serves as the first line of defense for clearing of the DNA damage and preventing mutation. Other biological pathways discussed here that are activated by genotoxic stress include post-translational activation of cell cycle networks and transcriptional networks for apoptosis/cell death. The interactions of various DNA repair and DNA damage response pathways provide biological bases for the observed PoD behaviors seen with genotoxic compounds. Thus, after formation of DNA adducts, the activation of cellular pathways can lead to the avoidance a mutagenic outcome. The understanding of the cellular mechanisms acting within the low-dose region will serve to better characterize risks from exposures to DNA-reactive agents at environmentally-relevant concentrations. PMID:27036068

  6. Tensile Deformation and Adiabatic Heating in Post-Yield Response of Polycarbonate

    Science.gov (United States)

    2015-11-01

    strain histories for max and gage length and b) stress-strain behavior of PC at intermediate rate for max and gage length 8 3.4 Rate Effects on... frame . To determine the variations in yield and post-yield response at different locations of the gage area of the specimen, digital image...significant rate-sensitive mechanical response. 15. SUBJECT TERMS polycarbonate, tension, rate effects , thermal, heating 16. SECURITY CLASSIFICATION OF

  7. A non-linear association between self-reported negative emotional response to stress and subsequent allostatic load

    DEFF Research Database (Denmark)

    Dich, Nadya; Doan, Stacey N; Kivimäki, Mika

    2014-01-01

    Previous research suggests that high levels of negative emotions may affect health. However, it is likely that the absence of an emotional response following stressful events may also be problematic. Accordingly, we investigated whether a non-linear association exists between negative emotional...... cardiovascular, metabolic and immune function biomarkers at three clinical follow-up examinations. A non-linear association between negative emotional response and allostatic load was observed: being at either extreme end of the distribution of negative emotional response increased the risk of physiological...

  8. Continuous-flow multi-analyte biosensor cartridge with controllable linear response range.

    Science.gov (United States)

    Frey, Olivier; Talaei, Sara; van der Wal, Peter D; Koudelka-Hep, Milena; de Rooij, Nico F

    2010-09-01

    This article presents the design and fabrication of a microfluidic biosensor cartridge for the continuous and simultaneous measurement of biologically relevant analytes in a sample solution. The biosensor principle is based on the amperometric detection of hydrogen peroxide using enzyme-modified electrodes. The low-integrated and disposable cartridge is fabricated in PDMS and SU-8 by rapid prototyping. The device is designed in such a way that it addresses two major challenges of biosensors using microfluidics approaches. Firstly, the enzymatic membrane is deposited on top of the platinum electrodes via a microfluidic deposition channel from outside the cartridge. This decouples the membrane deposition from the cartridge fabrication and enables the user to decide when and with what mixture he wants to modify the electrode. Secondly, by using laminar sheath-flow of the sample and a buffer solution, a dynamic diffusion layer is created. The analyte has to diffuse through the buffer solution layer before it can reach the immobilized enzyme membrane on the electrode. Controlling of the thickness of the diffusion layer by variation of the flow-rate of the two layers enables the user to adjust the sensitivity and the linear region of the sensor. The point where the buffer and sample stream join proved critical in creating the laminar sheath-flow. Results of computational simulations considering fluid dynamics and diffusion are presented. The consistency of the device was investigated through detection of glucose and lactate and are in accordance with the CFD simulations. A sensitivity of 157+/-28 nA/mM for the glucose sensor and 79+/-12 nA/mM for the lactate sensor was obtained. The linear response range of these biosensors could be increased from initially 2 mM up to 15 mM with a limit of detection of 0.2 mM.

  9. Non-linear CO2 flux response to seven years of experimentally induced permafrost thaw.

    Science.gov (United States)

    Mauritz, Marguerite; Bracho, Rosvel; Celis, Gerardo; Hutchings, Jack; Natali, Susan M; Pegoraro, Elaine; Salmon, Verity G; Schädel, Christina; Webb, Elizabeth E; Schuur, Edward A G

    2017-02-16

    Rapid Arctic warming is expected to increase global greenhouse gas concentrations as permafrost thaw exposes immense stores of frozen carbon (C) to microbial decomposition. Permafrost thaw also stimulates plant growth, which could offset C loss. Using data from seven years of experimental Air and Soil warming in moist acidic tundra, we show that Soil warming had a much stronger effect on CO2 flux than Air warming. Soil warming caused rapid permafrost thaw and increased ecosystem respiration (Reco), gross primary productivity (GPP), and net summer CO2 storage (NEE). Over seven years Reco, GPP, and NEE also increased in Control (i.e., ambient plots), but this change could be explained by slow thaw in Control areas. In the initial stages of thaw, Reco , GPP, and NEE increased linearly with thaw across all treatments, despite different rates of thaw. As thaw in Soil warming continued to increase linearly, ground surface subsidence created saturated micro-sites, and suppressed Reco , GPP, and NEE. However Reco and GPP remained high in areas with large Eriophorum vaginatum biomass. In general NEE increased with thaw, but was more strongly correlated with plant biomass than thaw, indicating that higher Reco in deeply thawed areas during summer months was balanced by GPP. Summer CO2 flux across treatments fit a single quadratic relationship that captured the functional response of CO2 flux to thaw, water table depth, and plant biomass. These results demonstrate the importance of indirect thaw effects on CO2 flux: plant growth and water table dynamics. Non-summer Reco models estimated that the area was an annual CO2 source during all years of observation. Non-summer CO2 loss in warmer, more deeply thawed soils exceeded the increases in summer GPP, and thawed tundra was a net annual CO2 source. This article is protected by copyright. All rights reserved.

  10. Responses of Varroa-resistant honey bees (Apis mellifera L.) to Deformed wing virus

    Science.gov (United States)

    The negative impact of Deformedwing virus (DWV) on European honey bees Apis mellifera is magnified by Varroa destructor parasitism. This study compared the responses of two Varroa-resistant honey bee stocks, pure Russian honey bees (RHB) and out-crossed Varroa Sensitive Hygienic bees, Pol-line (POL)...

  11. Optical nonlinear response function with linear and diagonal quadratic electron-vibration coupling in mixed quantum-classical systems.

    Science.gov (United States)

    Toutounji, Mohamad

    2005-03-22

    While an optical linear response function of linearly and quadratically coupled mixed quantum-classical condensed-phase systems was derived by Toutounji [J. Chem. Phys. 121, 2228 (2004)], the corresponding analytical optical line shape is derived. The respective nonlinear correlation functions are also derived. Model calculations involving photon-echo, pump-probe, and hole-burning signals of model systems with both linear and quadratic coupling are provided. Hole-burning formula of Hayes-Small is compared to that of Mukamel in mixed quantum-classical systems.

  12. Optimization of linear-logarithmic CMOS image sensor using a photogate and a cascode MOSFET for reducing pixel response variation

    Science.gov (United States)

    Bae, Myunghan; Choi, Byoung-Soo; Kim, Sang-Hwan; Lee, Jimin; Oh, Chang-Woo; Shin, Jang-Kyoo

    2017-02-01

    Recently, CMOS image sensors (CISs) have become more and more complex because they require high-performances such as wide dynamic range, low-noise, high-speed operation, high-resolution and so on. First of all, wide dynamic range (WDR) is the first requirement for high-performance CIS. Several techniques have been proposed to improve the dynamic range. Although logarithmic pixel can achieve wide dynamic range, it leads to a poor signal-to-noise ratio due to small output swings. Furthermore, the fixed pattern noise of logarithmic pixel is significantly greater compared with other CISs. In this paper, we propose an optimized linear-logarithmic pixel. Compared to a conventional 3-transistor active pixel sensor structure, the proposed linear-logarithmic pixel is using a photogate and a cascode MOSFET in addition. The photogate which is surrounding a photodiode carries out change of sensitivity in the linear response and thus increases the dynamic range. The logarithmic response is caused by a cascode MOSFET. Although the dynamic range of the pixel has been improved, output curves of each pixel were not uniform. In general, as the number of devices increases in the pixel, pixel response variation is more pronounced. Hence, we optimized the linear-logarithmic pixel structure to minimize the pixel response variation. We applied a hard reset method and an optimized cascode MOSFET to the proposed pixel for reducing pixel response variation. Unlike the conventional reset operation, a hard reset using a p-type MOSFET fixes the voltage of each pixel to the same voltage. This reduces non-uniformity of the response in the linear response. The optimized cascode MOSFET achieves less variation in the logarithmic response. We have verified that the optimized pixel shows more uniform response than the conventional pixel, by both simulation and experiment.

  13. Nucleus pulposus deformation in response to rotation at L1-2 and L4-5.

    Science.gov (United States)

    Fazey, Peter J; Song, Swithin; Price, Roger I; Singer, Kevin P

    2013-06-01

    Spinal rotation couples with lateral flexion as a composite movement. Few data report the in vivo mechanical deformation of the nucleus pulposus following sustained rotation. MRI provides a non-invasive method of examining nucleus pulposus deformation by mapping the hydration signal distribution within the intervertebral disc. T1 weighted coronal and sagittal lumbar images and T2 weighted axial images at L1-2 and L4-5 were obtained from 10 asymptomatic subjects (mean age 29, range: 24-34 years) in sustained flexed and extended positions plus combined positions of left rotation with flexion and extension. Nucleus pulposus deformation was tracked by mapping the change in hydration profiles from coronal and sagittal pixel measurements. An average sagittal change in position of 44° (SD 14.5°) from flexion to extension was recorded between L1 and S1 (range: 18°- 60°) resulting in a mean anterior nucleus pulposus deformation of 16% of disc hydration profile (range: 3.5%-19%) in 19/20 discs. When rotation was combined with either flexion or extension, mean coronal deformation was 4.8% (SD-5.1%; range: 0.4%-15%). Lateral nucleus pulposus deformation direction varied in rotation (44% deformed left and 56% deformed right). Intersegmental lateral flexion direction more strongly predicted nucleus pulposus deformation direction with 75% deforming contralaterally. Nucleus pulposus deformation direction in young subjects was more predictable following sagittal position change than in rotation combined with flexion or extension. Deformation magnitude was reduced in rotated positions. Intersegmental lateral flexion was a stronger predictor of nucleus pulposus deformation direction. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Extrusion die geometry effects on the energy absorbing properties and deformation response of 6063-type Al-Mg-Si aluminum alloy

    Science.gov (United States)

    Gbenebor, O. P.; Fayomi, O. S. I.; Popoola, A. P. I.; Inegbenebor, A. O.; Oyawale, F.

    The response of 6063-type Al-Mg-Si alloy to deformation via extrusion was studied using tool steel dies with 15°, 30°, 45°, 60° and 75° entry angles. Compressive loads were subjected to each sample using the AVERY DENISON machine, adapted to supply a compressive load on the punch. The ability of the extrudate to absorb energy before fracture was calculated by integrating numerically the polynomial relationship between the compressive stress and sample strains. Strain rate was calculated for each specimen and the deformation zone length was mathematically derived from the die geometry to decipher its influence on both lateral and axial deformations. Results showed that extruding with a 15° die was the fastest as a result of the low flow stress encountered. Outstanding compressive strength, plastic deformation, strain rate and energy absorbing capacity were observed for the alloy extruded with a 75° die angle. Increase in die angles led to a decrease in deformation zone length and samples deformed more in the axial direction than in the lateral except for the 45o die which showed the opposite; the sample also showed the least ductility.

  15. Diffeomorphic Statistical Deformation Models

    DEFF Research Database (Denmark)

    Hansen, Michael Sass; Hansen, Mads/Fogtman; Larsen, Rasmus

    2007-01-01

    In this paper we present a new method for constructing diffeomorphic statistical deformation models in arbitrary dimensional images with a nonlinear generative model and a linear parameter space. Our deformation model is a modified version of the diffeomorphic model introduced by Cootes et al. Th...... with ground truth in form of manual expert annotations, and compared to Cootes's model. We anticipate applications in unconstrained diffeomorphic synthesis of images, e.g. for tracking, segmentation, registration or classification purposes....

  16. The non-linear response of a muscle in transverse compression: assessment of geometry influence using a finite element model.

    Science.gov (United States)

    Gras, Laure-Lise; Mitton, David; Crevier-Denoix, Nathalie; Laporte, Sébastien

    2012-01-01

    Most recent finite element models that represent muscles are generic or subject-specific models that use complex, constitutive laws. Identification of the parameters of such complex, constitutive laws could be an important limit for subject-specific approaches. The aim of this study was to assess the possibility of modelling muscle behaviour in compression with a parametric model and a simple, constitutive law. A quasi-static compression test was performed on the muscles of dogs. A parametric finite element model was designed using a linear, elastic, constitutive law. A multi-variate analysis was performed to assess the effects of geometry on muscle response. An inverse method was used to define Young's modulus. The non-linear response of the muscles was obtained using a subject-specific geometry and a linear elastic law. Thus, a simple muscle model can be used to have a bio-faithful, biomechanical response.

  17. Calculation of excitation energies from the CC2 linear response theory using Cholesky decomposition.

    Science.gov (United States)

    Baudin, Pablo; Sánchez Marín, José; García Cuesta, Inmaculada; Sánchez de Merás, Alfredo M J

    2014-03-14

    A new implementation of the approximate coupled cluster singles and doubles CC2 linear response model is reported. It employs a Cholesky decomposition of the two-electron integrals that significantly reduces the computational cost and the storage requirements of the method compared to standard implementations. Our algorithm also exploits a partitioning form of the CC2 equations which reduces the dimension of the problem and avoids the storage of doubles amplitudes. We present calculation of excitation energies of benzene using a hierarchy of basis sets and compare the results with conventional CC2 calculations. The reduction of the scaling is evaluated as well as the effect of the Cholesky decomposition parameter on the quality of the results. The new algorithm is used to perform an extrapolation to complete basis set investigation on the spectroscopically interesting benzylallene conformers. A set of calculations on medium-sized molecules is carried out to check the dependence of the accuracy of the results on the decomposition thresholds. Moreover, CC2 singlet excitation energies of the free base porphin are also presented.

  18. Adding salt to a surfactant solution: Linear rheological response of the resulting morphologies

    Energy Technology Data Exchange (ETDEWEB)

    Gaudino, Danila; Pasquino, Rossana, E-mail: r.pasquino@unina.it; Grizzuti, Nino [DICMaPI, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli (Italy)

    2015-11-15

    The micellar system composed of Cetylpyridinium Chloride-Sodium Salicylate (CPyCl-NaSal) in brine aqueous solutions has been studied by systematically changing the salt concentration, in order to investigate the rheology of the arising morphologies. In particular, the zero-shear viscosity and the linear viscoelastic response have been measured as a function of the NaSal concentration (with [CPyCl] = 100 mM). The Newtonian viscosity shows a nonmonotonic dependence upon concentration, passing through a maximum at NaSal/CPyCl ≈ 0.6, and eventually dropping at higher salt concentrations. The progressive addition of salt determines first a transition from a Newtonian to a purely Maxwell-like behavior as the length of the micelles significantly increases. Beyond the peak viscosity, the viscoelastic data show two distinct features. On the one hand, the main relaxation time of the system strongly decreases, while the plateau modulus remains essentially constant. Calculations based on the rheological data show that, as the binding salt concentration increases, there is a decrease in micelles breaking rate and a decrease in their average length. On the other hand, in the same concentration region, a low-frequency elastic plateau is measured. Such a plateau is considered as the signature of a tenuous, but persistent branched network, whose existence is confirmed by cryo-transmission electron microscopy images.

  19. Midpoint Distribution of Directed Polymers in the Stationary Regime: Exact Result Through Linear Response

    Science.gov (United States)

    Maes, Christian; Thiery, Thimothée

    2017-09-01

    We obtain an exact result for the midpoint probability distribution function (pdf) of the stationary continuum directed polymer, when averaged over the disorder. It is obtained by relating that pdf to the linear response of the stochastic Burgers field to some perturbation. From the symmetries of the stochastic Burgers equation we derive a fluctuation-dissipation relation so that the pdf gets given by the stationary two space-time points correlation function of the Burgers field. An analytical expression for the latter was obtained by Imamura and Sasamoto (J Stat Phys 150:908-939, 2013), thereby rendering our result explicit. In the large length limit that implies that the pdf is nothing but the scaling function f_{KPZ}(y) introduced by Prähofer and Spohn (J Stat Phys 115(1):255-279, 2004). Using the KPZ-universality paradigm, we find that this function can therefore also be interpreted as the pdf of the position y of the maximum of the Airy process minus a parabola and a two-sided Brownian motion. We provide a direct numerical test of the result through simulations of the Log-Gamma polymer.

  20. Energy loss of ions in a magnetized plasma: conformity between linear response and binary collision treatments.

    Science.gov (United States)

    Nersisyan, H B; Zwicknagel, G; Toepffer, C

    2003-02-01

    The energy loss of a heavy ion moving in a magnetized electron plasma is considered within the linear response (LR) and binary collision (BC) treatments with the purpose to look for a connection between these two models. These two complementary approaches yield close results if no magnetic field is present, but there develop discrepancies with growing magnetic field at ion velocities that are lower than, or comparable with, the thermal velocity of the electrons. We show that this is a peculiarity of the Coulomb interaction which requires cutoff procedures to account for its singularity at the origin and its infinite range. The cutoff procedures in the LR and BC treatments are different as the order of integrations in velocity and in ordinary (Fourier) spaces is reversed in both treatments. While BC involves a velocity average of Coulomb logarithms, there appear in LR Coulomb logarithms of velocity averaged cutoffs. The discrepancies between LR and BC vanish, except for small contributions of collective modes, for smoothened potentials that require no cutoffs. This is shown explicitly with the help of an improved BC in which the velocity transfer is treated up to second order in the interaction in Fourier space.

  1. Time-dependent density functional theory of open quantum systems in the linear-response regime.

    Science.gov (United States)

    Tempel, David G; Watson, Mark A; Olivares-Amaya, Roberto; Aspuru-Guzik, Alán

    2011-02-21

    Time-dependent density functional theory (TDDFT) has recently been extended to describe many-body open quantum systems evolving under nonunitary dynamics according to a quantum master equation. In the master equation approach, electronic excitation spectra are broadened and shifted due to relaxation and dephasing of the electronic degrees of freedom by the surrounding environment. In this paper, we develop a formulation of TDDFT linear-response theory (LR-TDDFT) for many-body electronic systems evolving under a master equation, yielding broadened excitation spectra. This is done by mapping an interacting open quantum system onto a noninteracting open Kohn-Sham system yielding the correct nonequilibrium density evolution. A pseudoeigenvalue equation analogous to the Casida equations of the usual LR-TDDFT is derived for the Redfield master equation, yielding complex energies and Lamb shifts. As a simple demonstration, we calculate the spectrum of a C(2 +) atom including natural linewidths, by treating the electromagnetic field vacuum as a photon bath. The performance of an adiabatic exchange-correlation kernel is analyzed and a first-order frequency-dependent correction to the bare Kohn-Sham linewidth based on the Görling-Levy perturbation theory is calculated.

  2. Long-term linear growth of children with severe steroid-responsive nephrotic syndrome.

    Science.gov (United States)

    Emma, Francesco; Sesto, Antonella; Rizzoni, Gianfranco

    2003-08-01

    The present study was designed to evaluate the risk of permanent linear growth impairment in a selected group of 42 children with steroid-dependent nephrotic syndrome (SDNS) and 14 children with frequently relapsing nephrotic syndrome (FRNS). Longitudinal height measurements were available in all patients from the onset of the disease for a mean follow-up of 11.7+/-3.5 years. During the prepubertal period, patients lost 0.49+/-0.6 height SD score (HtSDS) ( P<0.001). Twenty-three patients have reached their final height with an average loss of 0.92+/-0.8 HtSDS from the onset of their disease ( P<0.001) and 0.68+/-0.7 from their target HtSDS ( P<0.001). The pubertal growth spurt was mildly delayed in male but not female patients. Steroid therapy, calculated as the mean duration of prednisone (PDN) treatment or as the average cumulative PDN dose, was the only predictor of poor growth evolution. Partial catch-up growth occurred after PDN withdrawal. Children with early onset NS and adolescent patients, who were still receiving PDN after the age of 9 years in girls and 11 years in boys, were at higher risk for HtSDS loss. In conclusion, children with severe steroid-responsive NS are at risk of permanent growth retardation secondary to prolonged courses of steroid treatment.

  3. Lifespan and oxidative stress show a non-linear response to atmospheric oxygen in Drosophila.

    Science.gov (United States)

    Rascón, Brenda; Harrison, Jon F

    2010-10-15

    Oxygen provides the substrate for most ATP production, but also serves as a source of reactive oxygen species (ROS), which can induce cumulative macromolecular oxidative damage and cause aging. Pure oxygen atmospheres (100 kPa) are known to strongly reduce invertebrate lifespan and induce aging-related physiological changes. However, the nature of the relationship between atmospheric oxygen, oxidative stress, and lifespan across a range of oxygen levels is poorly known. Developmental responses are likely to play a strong role, as prior research has shown strong effects of rearing oxygen level on growth, size and respiratory system morphology. In this study, we examined (1) the effect of oxygen on adult longevity and (2) the effect of the oxygen concentration experienced by larvae on adult lifespan by rearing Drosophila melanogaster in three oxygen atmospheres throughout larval development (10, 21 and 40 kPa), then measuring the lifespan of adults in five oxygen tensions (2, 10, 21, 40, 100 kPa). We also assessed the rate of protein carbonyl production for flies kept at 2, 10, 21, 40 and 100 kPa as adults (all larvae reared in normoxia). The rearing of juveniles in varying oxygen treatments affected lifespan in a complex manner, and the effect of different oxygen tensions on adult lifespan was non-linear, with reduced longevity and heightened oxidative stress at extreme high and low atmospheric oxygen levels. Moderate hypoxia (10 kPa) extended maximum, but not mean lifespan.

  4. Wavelet-Based Linear-Response Time-Dependent Density-Functional Theory

    CERN Document Server

    Natarajan, Bhaarathi; Casida, Mark E; Deutsch, Thierry; Burchak, Olga N; Philouze, Christian; Balakirev, Maxim Y

    2011-01-01

    Linear-response time-dependent (TD) density-functional theory (DFT) has been implemented in the pseudopotential wavelet-based electronic structure program BigDFT and results are compared against those obtained with the all-electron Gaussian-type orbital program deMon2k for the calculation of electronic absorption spectra of N2 using the TD local density approximation (LDA). The two programs give comparable excitation energies and absorption spectra once suitably extensive basis sets are used. Convergence of LDA density orbitals and orbital energies to the basis-set limit is significantly faster for BigDFT than for deMon2k. However the number of virtual orbitals used in TD-DFT calculations is a parameter in BigDFT, while all virtual orbitals are included in TD-DFT calculations in deMon2k. As a reality check, we report the x-ray crystal structure and the measured and calculated absorption spectrum (excitation energies and oscillator strengths) of the small organic molecule N-cyclohexyl-2-(4-methoxyphenyl)imidaz...

  5. A shear deformable theory of laminated composite shallow shell-type panels and their response analysis. II - Static response

    Science.gov (United States)

    Khdeir, A. A.; Librescu, L.; Frederick, D.

    1989-01-01

    In the second part of this paper, by using the static counterparts of the governing equations derived in Librescu (1989), the static response of shallow composite shell-type panels subjected to a sinusoidal transverse load is investigated. The numerical applications, encompassing a large number of boundary conditions and various lamination schemes, allow one to obtain some conclusions which are formulated in the paper.

  6. Equivalent linear and nonlinear site response analysis for design and risk assessment of safety-related nuclear structures

    Energy Technology Data Exchange (ETDEWEB)

    Bolisetti, Chandrakanth, E-mail: cb76@buffalo.edu [University at Buffalo, The State University of New York, North Campus, 212 Ketter Hall, Amherst, NY 14260 (United States); Whittaker, Andrew S., E-mail: awhittak@buffalo.edu [University at Buffalo, The State University of New York, North Campus, 212 Ketter Hall, Amherst, NY 14260 (United States); Mason, H. Benjamin, E-mail: ben.mason@oregonstate.edu [Oregon State University, 101 Kearney Hall, Corvallis, OR 97331 (United States); Almufti, Ibrahim, E-mail: ibrahim.almufti@arup.com [Advanced Technology + Research, ARUP, 560 Mission Street, Suite 700, San Francisco, CA (United States); Willford, Michael, E-mail: michael.willford@arup.com [Advanced Technology + Research, ARUP, 560 Mission Street, Suite 700, San Francisco, CA (United States)

    2014-08-15

    Highlights: • Performed equivalent linear and nonlinear site response analyses using industry-standard numerical programs. • Considered a wide range of sites and input ground motions. • Noted the practical issues encountered while using these programs. • Examined differences between the responses calculated from different programs. • Results of biaxial and uniaxial analyses are compared. - Abstract: Site response analysis is a precursor to soil-structure interaction analysis, which is an essential component in the seismic analysis of safety-related nuclear structures. Output from site response analysis provides input to soil-structure interaction analysis. Current practice in calculating site response for safety-related nuclear applications mainly involves the equivalent linear method in the frequency-domain. Nonlinear time-domain methods are used by some for the assessment of buildings, bridges and petrochemical facilities. Several commercial programs have been developed for site response analysis but none of them have been formally validated for large strains and high frequencies, which are crucial for the performance assessment of safety-related nuclear structures. This study sheds light on the applicability of some industry-standard equivalent linear (SHAKE) and nonlinear (DEEPSOIL and LS-DYNA) programs across a broad range of frequencies, earthquake shaking intensities, and sites ranging from stiff sand to hard rock, all with a focus on application to safety-related nuclear structures. Results show that the equivalent linear method is unable to reproduce the high frequency acceleration response, resulting in almost constant spectral accelerations in the short period range. Analysis using LS-DYNA occasionally results in some unrealistic high frequency acceleration ‘noise’, which can be removed by smoothing the piece-wise linear backbone curve. Analysis using DEEPSOIL results in abrupt variations in the peak strains of consecutive soil layers

  7. Evolution of Channels Draining Mount St. Helens: Linking Non-Linear and Rapid, Threshold Responses

    Science.gov (United States)

    Simon, A.

    2010-12-01

    The catastrophic eruption of Mount St. Helens buried the valley of the North Fork Toutle River (NFT) to a depth of up to 140 m. Initial integration of a new drainage network took place episodically by the “filling and spilling” (from precipitation and seepage) of depressions formed during emplacement of the debris avalanche deposit. Channel incision to depths of 20-30 m occurred in the debris avalanche and extensive pyroclastic flow deposits, and headward migration of the channel network followed, with complete integration taking place within 2.5 years. Downstream reaches were converted from gravel-cobble streams with step-pool sequences to smoothed, infilled channels dominated by sand-sized materials. Subsequent channel evolution was dominated by channel widening with the ratio of changes in channel width to changes in channel depth ranging from about 60 to 100. Widening resulted in significant adjustment of hydraulic variables that control sediment-transport rates. For a given discharge over time, flow depths were reduced, relative roughness increased and flow velocity and boundary shear stress decreased non-linearly. These changes, in combination with coarsening of the channel bed with time resulted in systematically reduced rates of degradation (in upstream reaches), aggradation (in downstream reaches) and sediment-transport rates through much of the 1990s. Vertical adjustments were, therefore, easy to characterize with non-linear decay functions with bed-elevation attenuating with time. An empirical model of bed-level response was then created by plotting the total dimensionless change in elevation against river kilometer for both initial and secondary vertical adjustments. High magnitude events generated from the generated from upper part of the mountain, however, can cause rapid (threshold) morphologic changes. For example, a rain-on-snow event in November 2006 caused up to 9 m of incision along a 6.5 km reach of Loowit Creek and the upper NFT. The event

  8. Frequency Response of Synthetic Vocal Fold Models with Linear and Nonlinear Material Properties

    Science.gov (United States)

    Shaw, Stephanie M.; Thomson, Scott L.; Dromey, Christopher; Smith, Simeon

    2012-01-01

    Purpose: The purpose of this study was to create synthetic vocal fold models with nonlinear stress-strain properties and to investigate the effect of linear versus nonlinear material properties on fundamental frequency (F[subscript 0]) during anterior-posterior stretching. Method: Three materially linear and 3 materially nonlinear models were…

  9. An introduction to linear ordinary differential equations using the impulsive response method and factorization

    CERN Document Server

    Camporesi, Roberto

    2016-01-01

    This book presents a method for solving linear ordinary differential equations based on the factorization of the differential operator. The approach for the case of constant coefficients is elementary, and only requires a basic knowledge of calculus and linear algebra. In particular, the book avoids the use of distribution theory, as well as the other more advanced approaches: Laplace transform, linear systems, the general theory of linear equations with variable coefficients and variation of parameters. The case of variable coefficients is addressed using Mammana’s result for the factorization of a real linear ordinary differential operator into a product of first-order (complex) factors, as well as a recent generalization of this result to the case of complex-valued coefficients.

  10. A discrete solvent reaction field model for calculating molecular linear response properties in solution

    Science.gov (United States)

    Jensen, Lasse; van Duijnen, Piet Th.; Snijders, Jaap G.

    2003-08-01

    A discrete solvent reaction field model for calculating frequency-dependent molecular linear response properties of molecules in solution is presented. The model combines a time-dependent density functional theory (QM) description of the solute molecule with a classical (MM) description of the discrete solvent molecules. The classical solvent molecules are represented using distributed atomic charges and polarizabilities. All the atomic parameters have been chosen so as to describe molecular gas phase properties of the solvent molecule, i.e., the atomic charges reproduce the molecular dipole moment and the atomic polarizabilities reproduce the molecular polarizability tensor using a modified dipole interaction model. The QM/MM interactions are introduced into the Kohn-Sham equations and all interactions are solved self-consistently, thereby allowing for the solute to be polarized by the solvent. Furthermore, the inclusion of polarizabilities in the MM part allows for the solvent molecules to be polarized by the solute and by interactions with other solvent molecules. Initial applications of the model to calculate the vertical electronic excitation energies and frequency-dependent molecular polarizability of a water molecule in a cluster of 127 classical water molecules are presented. The effect of using different exchange correlation (xc)-potentials is investigated and the results are compared with results from wave function methods combined with a similar solvent model both at the correlated and uncorrelated level of theory. It is shown that accurate results in agreement with correlated wave function results can be obtained using xc-potentials with the correct asymptotic behavior.

  11. Self-characterization of linear and nonlinear adaptive optics systems

    Science.gov (United States)

    Hampton, Peter J.; Conan, Rodolphe; Keskin, Onur; Bradley, Colin; Agathoklis, Pan

    2008-01-01

    We present methods used to determine the linear or nonlinear static response and the linear dynamic response of an adaptive optics (AO) system. This AO system consists of a nonlinear microelectromechanical systems deformable mirror (DM), a linear tip-tilt mirror (TTM), a control computer, and a Shack-Hartmann wavefront sensor. The system is modeled using a single-input-single-output structure to determine the one-dimensional transfer function of the dynamic response of the chain of system hardware. An AO system has been shown to be able to characterize its own response without additional instrumentation. Experimentally determined models are given for a TTM and a DM.

  12. Diluted bitumen causes deformities and molecular responses indicative of oxidative stress in Japanese medaka embryos.

    Science.gov (United States)

    Madison, Barry N; Hodson, P V; Langlois, V S

    2015-08-01

    This study characterized the toxicity and physiological effects of unweathered diluted bitumen (Access Western Blend dilbit; AWB) to fish. Embryos of Japanese medaka (Oryzias latipes) were exposed for 17 days to dilutions of physically-dispersed (water accommodated fraction; WAF) and chemically-dispersed (chemically-enhanced WAF; CEWAF) dilbit. AWB dilbit exposure was not lethal to medaka, but resulted in a high prevalence of blue sac disease (BSD), impaired development, and abnormal or un-inflated swim bladders at hatch. Physiological effects were indicated by the relative mRNA levels of key genes associated with, among others, cell cycling and the response to mutations (p53), xenobiotic metabolism (ahr, arnt2), phase I (cyp1a) and II processes associated with oxidative stress (cat, g6pdh, hsp70, gst, gpx, gsr, nfe2, and sod). AWB dilbit treatment increased p53 and cyp1a transcript levels (1.5-fold and >15-fold, respectively), with significant, but less pronounced changes in indicators of oxidative stress and metabolism. The exposure-related changes in embryotoxicity and mRNA synthesis were consistent with metabolism of polycyclic aromatic hydrocarbons (PAHs) to reactive and toxic metabolites. Medaka embryos responded similarly to WAF and CEWAF treatments, but CEWAF was about 100 times more efficient in delivering toxic concentrations of PAHs. The toxicity of chemically-dispersed nujol, a non-toxic mineral oil used as an experimental control, suggested that a portion of the observed effects of AWB could be attributed to excess dispersant in solution. This first study of the physiological effects of dilbit toxicity to fish embryos provides a baseline to compare toxicity between dilbit and conventional crude oils, and the groundwork for the development of molecular biomarkers of the sensitivity and level of risk of native Canadian fish species to dilbit exposure.

  13. The horizontal angular vestibulo-ocular reflex: a non-linear mechanism for context-dependent responses.

    Science.gov (United States)

    Ranjbaran, Mina; Galiana, Henrietta L

    2012-01-01

    A bilateral model for the horizontal angular vestibulo-ocular reflex (AVOR) is presented in this paper. It is shown that by assigning proper non-linear neural computations at the premotor level, the model is capable of replicating target-distance dependent VOR responses. Moreover, the model behavior in case of sensory plugging is also consistent with reported experimental observations.

  14. Further results on the disturbance response of a double integrator controlled by a saturating linear static state feedback

    NARCIS (Netherlands)

    Wang, Xu; Saberi, Ali; Stoorvogel, Anton A.; Grip, H°avard Fjær

    2012-01-01

    In this paper, we study the response to external disturbances of a double integrator with a saturating feedback. For a class of disturbances that have bounded integrals over all intervals, we show that a linear static feedback law can always be designed to ensure boundedness of the states. Moreover,

  15. Linear interference and the northern annular mode response to El Niño and climate change

    Science.gov (United States)

    Fletcher, Christopher G.; Minokhin, Ivan

    2015-12-01

    The northern annular mode (NAM) characterizes a significant fraction of wintertime climate variability in the Northern Hemisphere. Understanding the processes governing changes in the NAM on interannual and longer timescales is therefore of critical importance. Previous work reveals a consensus around the negative NAM response to El Niño events (ELN), but considerable disagreement among model projections of the NAM response to climate change (CC), despite the tropical oceans warming in both cases. This work presents numerical simulations with two atmospheric GCMs that reveal robust opposite-signed NAM responses to prescribed sea-surface temperature (SST) anomalies representing ELN (negative NAM) and CC (positive NAM). The primary driver of the sign and amplitude of the NAM response is the linear interference between the planetary waves generated in response to the SST perturbations, and the climatological stationary waves. However, the linear interference framework breaks down in the case involving CC, because the total wave driving of the NAM involves a balance between a strong negative contribution from the eddies related to linear interference, and a strong positive contribution from nonlinear and higher frequency eddies. In addition, the response to CC is less robust in the two models, which may be related to the models' parameterizations causing differences in the sensitivity to imposed SST anomalies.

  16. Non-linear response of electrode-electrolyte interface at high current density

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz, G.A. [Departamento de Bioingenieria, FACET-INSIBIO/UNT-CONICET, CC 327 Correo Central, 4000 Tucuman (Argentina)] e-mail: gruiz@herrera.unt.edu.ar; Felice, C.J. [Departamento de Bioingenieria, FACET-INSIBIO/UNT-CONICET, CC 327 Correo Central, 4000 Tucuman (Argentina); Valentinuzzi, M.E. [Departamento de Bioingenieria, FACET-INSIBIO/UNT-CONICET, CC 327 Correo Central, 4000 Tucuman (Argentina)

    2005-08-01

    A distributed parameter non-linear circuit is presented as fractal model of an electrode-electrolyte interface. It includes the charge transfer resistance and the double layer capacitance at each fractal level. The circuit explains the linear behavior of its series equivalent resistance R {sub eq} with signals of amplitudes <20 mV and constant frequency; however, for amplitudes beyond that limit, non-linearity is manifested in the dc component of the R {sub eq} Fourier spectrum. As a consequence, both the equivalent resistance and reactance drop with voltage, facts reported experimentally by other authors.

  17. Predicting the nonlinear optical response in the resonant region from the linear characterization: a self-consistent theory for the first-, second-, and third-order (non)linear optical response

    Science.gov (United States)

    Pérez-Moreno, Javier; Clays, Koen; Kuzyk, Mark G.

    2010-08-01

    We introduce a self-consistent theory for the description of the optical linear and nonlinear response of molecules that is based strictly on the results of the experimental characterization. We show how the Thomas-Kuhn sum-rules can be used to eliminate the dependence of the nonlinear response on parameters that are not directly measurable. Our approach leads to the successful modeling of the dispersion of the nonlinear response of complex molecular structures with different geometries (dipolar and octupolar), and can be used as a guide towards the modeling in terms of fundamental physical parameters.

  18. Wavefront correction with a ferrofluid deformable mirror: experimental results and recent developments

    CERN Document Server

    Brousseau, Denis; Thibaul, Simon; Ritcey, Anna M; Parent, Jocelyn; Seddiki, Omar; Dery, Jean-Philippe; Faucher, Luc; Vassallo, Julien; Naderian, Azadeh

    2008-01-01

    We present the research status of a deformable mirror made of a magnetic liquid whose surface is actuated by a triangular array of small current carrying coils. We demonstrate that the mirror can correct a 11 microns low order aberrated wavefront to a residual RMS wavefront error 0.05 microns. Recent developments show that these deformable mirrors can reach a frequency response of several hundred hertz. A new method for linearizing the response of these mirrors is also presented.

  19. Self-Produced Locomotion and the Development of Responsiveness to Linear Perspective and Texture Gradients.

    Science.gov (United States)

    Arterberry, Martha; And Others

    1989-01-01

    Results indicate that seven-month-old infants are sensitive to the depth cues of linear perspective and texture gradients. Self-produced locomotor experience is not necessary for the development of sensitivity to static-monocular depth information. (RJC)

  20. Step-response of a torsional device with multiple discontinuous non-linearities: Formulation of a vibratory experiment

    Science.gov (United States)

    Krak, Michael D.; Dreyer, Jason T.; Singh, Rajendra

    2016-03-01

    A vehicle clutch damper is intentionally designed to contain multiple discontinuous non-linearities, such as multi-staged springs, clearances, pre-loads, and multi-staged friction elements. The main purpose of this practical torsional device is to transmit a wide range of torque while isolating torsional vibration between an engine and transmission. Improved understanding of the dynamic behavior of the device could be facilitated by laboratory measurement, and thus a refined vibratory experiment is proposed. The experiment is conceptually described as a single degree of freedom non-linear torsional system that is excited by an external step torque. The single torsional inertia (consisting of a shaft and torsion arm) is coupled to ground through parallel production clutch dampers, which are characterized by quasi-static measurements provided by the manufacturer. Other experimental objectives address physical dimensions, system actuation, flexural modes, instrumentation, and signal processing issues. Typical measurements show that the step response of the device is characterized by three distinct non-linear regimes (double-sided impact, single-sided impact, and no-impact). Each regime is directly related to the non-linear features of the device and can be described by peak angular acceleration values. Predictions of a simplified single degree of freedom non-linear model verify that the experiment performs well and as designed. Accordingly, the benchmark measurements could be utilized to validate non-linear models and simulation codes, as well as characterize dynamic parameters of the device including its dissipative properties.

  1. Multiple linear regression to estimate time-frequency electrophysiological responses in single trials.

    Science.gov (United States)

    Hu, L; Zhang, Z G; Mouraux, A; Iannetti, G D

    2015-05-01

    Transient sensory, motor or cognitive event elicit not only phase-locked event-related potentials (ERPs) in the ongoing electroencephalogram (EEG), but also induce non-phase-locked modulations of ongoing EEG oscillations. These modulations can be detected when single-trial waveforms are analysed in the time-frequency domain, and consist in stimulus-induced decreases (event-related desynchronization, ERD) or increases (event-related synchronization, ERS) of synchrony in the activity of the underlying neuronal populations. ERD and ERS reflect changes in the parameters that control oscillations in neuronal networks and, depending on the frequency at which they occur, represent neuronal mechanisms involved in cortical activation, inhibition and binding. ERD and ERS are commonly estimated by averaging the time-frequency decomposition of single trials. However, their trial-to-trial variability that can reflect physiologically-important information is lost by across-trial averaging. Here, we aim to (1) develop novel approaches to explore single-trial parameters (including latency, frequency and magnitude) of ERP/ERD/ERS; (2) disclose the relationship between estimated single-trial parameters and other experimental factors (e.g., perceived intensity). We found that (1) stimulus-elicited ERP/ERD/ERS can be correctly separated using principal component analysis (PCA) decomposition with Varimax rotation on the single-trial time-frequency distributions; (2) time-frequency multiple linear regression with dispersion term (TF-MLRd) enhances the signal-to-noise ratio of ERP/ERD/ERS in single trials, and provides an unbiased estimation of their latency, frequency, and magnitude at single-trial level; (3) these estimates can be meaningfully correlated with each other and with other experimental factors at single-trial level (e.g., perceived stimulus intensity and ERP magnitude). The methods described in this article allow exploring fully non-phase-locked stimulus-induced cortical

  2. Seismic response of structures: from non-stationary to non-linear effects

    Science.gov (United States)

    Carlo Ponzo, Felice; Ditommaso, Rocco; Mucciarelli, Marco; Smith, Tobias

    2013-04-01

    The need for an effective seismic protection of buildings, and all the problems related to their management and maintenance over time, have led to a growing interest associated to develop of new integrated techniques for structural health monitoring and for damage detection and location during both ambient vibration and seismic events. It is well known that the occurrence of damage on any kind of structure is able to modify its dynamic characteristics. Indeed, the main parameters affected by the changes in stiffness characteristics are: periods of vibration, mode shapes and all the related equivalent viscous damping factors. With the aim to evaluate structural dynamic characteristics, their variation over time and after earthquakes, several Non Destructive Evaluation (NDE) methods have been proposed in the last years. Most of these are based on simplified relationship that provide the maximum inter-story drift evaluated combining structural variations in terms of: peak ground acceleration and/or structural eigenfrequencies and/or equivalent viscous damping factors related the main modes of the monitored structure. The NDE methods can be classified into four different levels. The progress of the level increases the quality and the number of the information. The most popular are certainly Level I methods being simple in implementation and economic in management. These kinds of methods are mainly based on the fast variation (less than 1 minute) of the structural fundamental frequency and the related variation of the equivalent viscous damping factor. Generally, it is possible to distinguish two types of variations: the long term variations, which may also be linked to external factors (temperature change, water content in the foundation soils, etc.) and short period variations (for example, due to seismic events), where apparent frequencies variations could occurred due to non-stationary phenomena (particular combination of input and structural response). In these

  3. A review of the effect of prior inelastic deformation on high temperature mechanical response of engineering alloys

    Energy Technology Data Exchange (ETDEWEB)

    Li, D.F. [Department of Mechanical and Aeronautical Engineering, Materials and Surface Science Institute, University of Limerick, Plassey Park, Limerick (Ireland); O' Dowd, N.P., E-mail: noel.odowd@ul.i [Department of Mechanical and Aeronautical Engineering, Materials and Surface Science Institute, University of Limerick, Plassey Park, Limerick (Ireland); Davies, C.M.; Nikbin, K.M. [Department of Mechanical Engineering, Imperial College London, United Kindom (United Kingdom)

    2010-10-15

    In this review article, we examine the influence of prior deformation (prestrain) on the subsequent high temperature mechanical behaviour of engineering alloys. We review the observed effects at a macroscopic level in terms of creep deformation, creep rupture times and crack growth rates from a number of sources and a range of materials. Microstructural explanations for the observed macroscopic effects are also reviewed and constitutive models which incorporate the effect of prior deformation are examined. The emphasis in the paper is on engineering steels though reference is also made to non-ferrous alloys.

  4. A Fast Method to Calculate the Spatial Impulse Response for 1-D Linear Ultrasonic Phased Array Transducers.

    Science.gov (United States)

    Zou, Cheng; Sun, Zhenguo; Cai, Dong; Muhammad, Salman; Zhang, Wenzeng; Chen, Qiang

    2016-11-08

    A method is developed to accurately determine the spatial impulse response at the specifically discretized observation points in the radiated field of 1-D linear ultrasonic phased array transducers with great efficiency. In contrast, the previously adopted solutions only optimize the calculation procedure for a single rectangular transducer and required approximation considerations or nonlinear calculation. In this research, an algorithm that follows an alternative approach to expedite the calculation of the spatial impulse response of a rectangular linear array is presented. The key assumption for this algorithm is that the transducer apertures are identical and linearly distributed on an infinite rigid plane baffled with the same pitch. Two points in the observation field, which have the same position relative to two transducer apertures, share the same spatial impulse response that contributed from corresponding transducer, respectively. The observation field is discretized specifically to meet the relationship of equality. The analytical expressions of the proposed algorithm, based on the specific selection of the observation points, are derived to remove redundant calculations. In order to measure the proposed methodology, the simulation results obtained from the proposed method and the classical summation method are compared. The outcomes demonstrate that the proposed strategy can speed up the calculation procedure since it accelerates the speed-up ratio which relies upon the number of discrete points and the number of the array transducers. This development will be valuable in the development of advanced and faster linear ultrasonic phased array systems.

  5. A Fast Method to Calculate the Spatial Impulse Response for 1-D Linear Ultrasonic Phased Array Transducers

    Directory of Open Access Journals (Sweden)

    Cheng Zou

    2016-11-01

    Full Text Available A method is developed to accurately determine the spatial impulse response at the specifically discretized observation points in the radiated field of 1-D linear ultrasonic phased array transducers with great efficiency. In contrast, the previously adopted solutions only optimize the calculation procedure for a single rectangular transducer and required approximation considerations or nonlinear calculation. In this research, an algorithm that follows an alternative approach to expedite the calculation of the spatial impulse response of a rectangular linear array is presented. The key assumption for this algorithm is that the transducer apertures are identical and linearly distributed on an infinite rigid plane baffled with the same pitch. Two points in the observation field, which have the same position relative to two transducer apertures, share the same spatial impulse response that contributed from corresponding transducer, respectively. The observation field is discretized specifically to meet the relationship of equality. The analytical expressions of the proposed algorithm, based on the specific selection of the observation points, are derived to remove redundant calculations. In order to measure the proposed methodology, the simulation results obtained from the proposed method and the classical summation method are compared. The outcomes demonstrate that the proposed strategy can speed up the calculation procedure since it accelerates the speed-up ratio which relies upon the number of discrete points and the number of the array transducers. This development will be valuable in the development of advanced and faster linear ultrasonic phased array systems.

  6. Formulation of the Linear Response Theory in Relativistic LAPW Method. Calculation of Forces in Alpha-Pu

    Energy Technology Data Exchange (ETDEWEB)

    Kutepov, A L

    2004-01-08

    Linear-response (LR) theory in combination with the first-principles band structure codes allows to calculate phonons in an efficient way. In this report a formalism which enables us to apply LR theory within an all-electron framework utilizing the relativistic full-potential linearized augmented plane-wave (RFLAPW) method is presented. As first part, the equations for the calculations of the atomic forces are given and they are used for the calculation of forces in {alpha}-Pu. As a second step, a complete set of formulaes for the dynamic matrices calculation is presented.

  7. Responses of the central nervous system to high linear energy transfer radiation: NSCOR project highlights

    Science.gov (United States)

    Nelson, Gregory; Fike, John; Limoli, Charles; Obenaus, André; Raber, Jacob; Soltesz, Ivan; Vlkolinský, Roman

    2014-01-01

    Overview: The five-university NSCOR project investigates the responses of the central nervous system to space-like charged particle exposure by evaluating: synaptic function, in vitro and in vivo neurogenesis, behavior and behaviorally induced gene expression, and oxidative stress of the mouse hippocampus and cultured neural precursor cells. To test the role of reactive oxygen species in mediating the effects of radiation exposure, we compare responses in a catalase overexpressing transgenic mouse strain to wild type. We also use computational models of the hippocampus in three dimensions, informed by experimental measurements, to provide insight into network behavior. Radiation exposure protocols include single, acute whole-body exposures to 1H, 28Si and 56Fe ions and mixed field exposures using 1H + 56Fe ions (24 h later). The animal models are 10-week-old C57BL/6J and MCATtg males which are evaluated at 30 and 90 days postirradiation. In vitro models are cultured murine and human neural stem cells irradiated with 1H, 16O, 28Si and 56Fe ions at multiple energies and are evaluated at times from days to weeks. Highlights: Neural stem cells organized into neurospheres were irradiated with several ions at doses as low as 0.75 cGy. Data show that significant oxidative stress occurs that alters survival, proliferation and differentiation. Overall trends indicate that changes in oxidative stress (persisting for weeks) correlate with particle linear energy transfer (LET). 56Fe ions elicited the largest and most persistent changes in stress markers, including antioxidant enzyme expression levels. The hippocampus-dependent contextual fear conditioning (CFC) and novel object recognition (NOR) paradigms were used to assess cognition and showed cognitive deficits after irradiation with the NOR paradigm more sensitive than CFC. Analysis of neurogenesis indicates that overall neurogenesis is inhibited at doses ≥1 Gy, but newly born activated microglia are significantly

  8. Note: An in situ method for measuring the non-linear response of a Fabry-Perot cavity

    Science.gov (United States)

    Bu, Wenhao; Liu, Mengke; Xie, Dizhou; Yan, Bo

    2016-09-01

    The transfer cavity is a very important frequency reference for laser stabilization and is widely used for applications such as precision measurements and laser cooling of ions or molecules. But the non-linear response of the piezoelectric ceramic transducer (PZT) in the Fabry-Perot cavity limits the performance of the laser stabilization. Thus, measuring and controlling such non-linearity is essential. Here we report an in situ, optical method to characterize this non-linearity by measuring the resonant signals of a dual-frequency laser. The differential measurement makes it insensitive to the laser and cavity drifts, while maintaining a very high sensitivity. It can be applied for various applications with PZTs, especially in an optical lab.

  9. An in-situ method for measuring the non-linear response of a Fabry-Perot cavity

    CERN Document Server

    Bu, Wenhao; Xie, Dizhou; Yan, Bo

    2016-01-01

    High finesse Fabry-Perot(FP) cavity is a very important frequency reference for laser stabiliza- tion, and is widely used for applications such as precision measurement, laser cooling of ions or molecules. But the non-linear response of the piezoelectric ceramic transducer (PZT) in the FP cav- ity limits the performance of the laser stabilization. Measuring and controlling such non-linearity are important. Here we report an in-situ, optical method to characterize this non-linearity by measuring the resonance signals of a dual-frequency laser. The di?erential measurement makes it insensitive to laser and cavity drifting, and has a very high sensitivity. It can be applied for various applications with PZT, especially in an optical lab.

  10. Linear and third-order nonlinear optical responses of multilayered Ag:Si{sub 3}N{sub 4} nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Toudert, J [Instituto de Ciencia de Materiales de Sevilla, CSIC, c/Americo Vespucio 49, Isla de la Cartuja, E-41092 Sevilla (Spain); Fernandez, H; Solis, J [Laser Processing Group, Instituto de Optica, CSIC, Serrano 121, E-28006 Madrid (Spain); Babonneau, D; Camelio, S; Girardeau, T, E-mail: johann.toudert@gmail.co [Laboratoire de Physique des Materiaux (PHYMAT), UMR CNRS 6630, Universite de Poitiers, Batiment SP2MI, Boulevard Marie et Pierre Curie, F-86962 Futuroscope Chasseneuil (France)

    2009-11-25

    The linear and third-order nonlinear responses of tailored Si{sub 3}N{sub 4}/Ag/Si{sub 3}N{sub 4} trilayers and (Si{sub 3}N{sub 4}/Ag){sub n}/Si{sub 3}N{sub 4} multilayers grown by alternating ion-beam sputtering have been studied by combining complementary characterization techniques such as transmission electron microscopy, spectroscopic ellipsometry and degenerate four-wave mixing. The linear optical response dominated by the surface plasmon resonance of Ag nanoparticles has been measured over the whole visible range while the third-order nonlinear susceptibility has been probed at the surface plasmon resonance wavelength. Due to the weak in-plane interaction between Ag nanoparticles, the linear and nonlinear optical responses of the Si{sub 3}N{sub 4}/Ag/Si{sub 3}N{sub 4} trilayers are mainly influenced by the size and shape of the nanoparticles. A maximum value of 1.1 x 10{sup -7} esu has been found at 635 nm for the effective third-order nonlinear susceptibility of the trilayer with the highest amount of silver. The linear optical response of the (Si{sub 3}N{sub 4}/Ag){sub n}/Si{sub 3}N{sub 4} multilayers is shown to be dominated by the surface plasmon resonance of isolated layers of weakly interacting nanoparticles at wavelengths shorter than 600 nm whereas a contribution due to vertical interactions has been shown for higher wavelengths. Below the vertical percolation threshold, their nonlinear optical response at the surface plasmon resonance wavelength is similar to the one of an isolated assembly of nanoparticles, and the effective third-order nonlinear susceptibility is slightly increased by decreasing the thickness of the Si{sub 3}N{sub 4} spacer.

  11. Response of Critical Speed to Different Macrocycle Phases during Linear Periodization on Young Swimmers

    Directory of Open Access Journals (Sweden)

    João Bartholomeu NETO

    2016-03-01

    Full Text Available Sport training programs to young swimmers have to aggregate different physical stimulus to collaborate with overall physical development, which can lead to reach best results in competitions. Linear periodization seems to be a powerful tool that allow the organization of these stimulus. However, this model has been not studied. Regarding physical capacities, aerobic fitness is inversely related with fatigue and exercise performance. Although aerobic capacity evaluation used to be expensive, critical speed (CS is easy and non - expensive tool capable to make this measurement. Thus, the aim of this study was evaluate the effects of linear periodization in CS on well - trained young swimmers. Sixteen athletes (age: 14.06  1.22 years, height: 163.52  10.99 cm, weight: 57.4  12.7 kg, body mass index: 21.24  37; 7 ♀, were underwent to a linear macrocycle training with 23 weeks divided in four mesocycles: general endurance (i.e., 4 weeks, specific endurance (i.e., 8 weeks, competitive (i.e., 7 weeks and taper (i.e., 4 weeks. Results showed significantly improve on CS after competitive and taper mesocycle phases, which was composed by higher training intensity in comparison with other macrocycle phases. Therefore, the results of the present study indicate a collaboration of mesocycle intensity on the cumulative effects of linear periodization in CS improve on young swimmers.

  12. Non-parametric system identification from non-linear stochastic response

    DEFF Research Database (Denmark)

    Rüdinger, Finn; Krenk, Steen

    2001-01-01

    An estimation method is proposed for identification of non-linear stiffness and damping of single-degree-of-freedom systems under stationary white noise excitation. Non-parametric estimates of the stiffness and damping along with an estimate of the white noise intensity are obtained by suitable p...

  13. Linear Viscoelastic and Dielectric Relaxation Response of Unentangled UPy-Based Supramolecular Networks

    DEFF Research Database (Denmark)

    Shabbir, Aamir; Javakhishvili, Irakli; Cerveny, Silvina

    2016-01-01

    Supramolecular polymers possess versatile mechanical properties and a unique ability to respond to external stimuli. Understanding the rich dynamics of such associative polymers is essential for tailoring user-defined properties in many products. Linear copolymers of 2-methoxyethyl acrylate (MEA)...

  14. Linear Viscoelastic and Dielectric Relaxation Response of Unentangled UPy-Based Supramolecular Networks

    DEFF Research Database (Denmark)

    Shabbir, Aamir; Javakhishvili, Irakli; Cerveny, Silvina;

    2016-01-01

    Supramolecular polymers possess versatile mechanical properties and a unique ability to respond to external stimuli. Understanding the rich dynamics of such associative polymers is essential for tailoring user-defined properties in many products. Linear copolymers of 2-methoxyethyl acrylate (MEA)...

  15. Response of Non-Linear Systems to Renewal Impulses by Path Integration

    DEFF Research Database (Denmark)

    Nielsen, Søren R.K.; Iwankiewicz, R.

    The cell-to-cell mapping (path integration) technique has been devised for MDOF non-linear and non-hysteretic systems subjected to random trains of impulses driven by an ordinary renewal point process with gamma-distributed integer parameter interarrival times (an Erlang process). Since the renewal...... additional discrete-valued state variables for which the stochastic equations are also formulated....

  16. Linear and nonlinear optical response of one-dimensional semiconductors: finite-size and Franz–Keldysh effects

    Science.gov (United States)

    Bonabi, Farzad; Pedersen, Thomas G.

    2017-04-01

    The dipole moment formalism for the optical response of finite electronic structures breaks down in infinite ones, for which a momentum-based method is better suited. Focusing on simple chain structures, we compare the linear and nonlinear optical response of finite and infinite one-dimensional semiconductors. This comparison is then extended to cases including strong electro-static fields breaking translational invariance. For large electro-static fields, highly non-perturbative Franz–Keldysh (FK) features are observed in both linear and nonlinear spectra. It is demonstrated that dipole and momentum formalisms agree in the limit of large structures provided the intraband momentum contributions are carefully treated. This convergence is established even in the presence of non-perturbative electro-static fields.

  17. Analytical expression for position sensitivity of linear response beam position monitor having inter-electrode cross talk

    Science.gov (United States)

    Kumar, Mukesh; Ojha, A.; Garg, A. D.; Puntambekar, T. A.; Senecha, V. K.

    2017-02-01

    According to the quasi electrostatic model of linear response capacitive beam position monitor (BPM), the position sensitivity of the device depends only on the aperture of the device and it is independent of processing frequency and load impedance. In practice, however, due to the inter-electrode capacitive coupling (cross talk), the actual position sensitivity of the device decreases with increasing frequency and load impedance. We have taken into account the inter-electrode capacitance to derive and propose a new analytical expression for the position sensitivity as a function of frequency and load impedance. The sensitivity of a linear response shoe-box type BPM has been obtained through simulation using CST Studio Suite to verify and confirm the validity of the new analytical equation. Good agreement between the simulation results and the new analytical expression suggest that this method can be exploited for proper designing of BPM.

  18. Calculation of vibrational energy of molecule using coupled cluster linear response theory in bosonic representation: convergence studies.

    Science.gov (United States)

    Banik, Subrata; Pal, Sourav; Prasad, M Durga

    2008-10-07

    Vibrational excited state energies have been calculated using vibrational coupled cluster linear response theory (CCLRT). The method has been implemented on formaldehyde and water molecule. Convergence studies have been shown with varying the cluster operator from S(4) to S(6) as well as the excitation operator from four bosons to six bosons. A good agreement with full configuration interaction results has been observed with S(6) truncation at coupled-cluster method level and six bosonic excitations at CCLRT level.

  19. Numerical tailoring of linear response from plasmonic nano-resonators grown on a layer of polystyrene spheres

    Energy Technology Data Exchange (ETDEWEB)

    Benedetti, A., E-mail: alessio.benedetti@uniroma1.it; Belardini, A.; Veroli, A.; Centini, M.; Sibilia, C. [Sapienza Università di Roma, Via A. Scarpa 14, I-00161 Roma (Italy)

    2014-10-28

    We developed a geometrical method to reproduce the morphology of hybrid structures composed by self-ordered dielectric nanospheres covered by anisotropic plasmonic structures. Numerical analysis allowed to investigate the optical response of the considered system, and to identify the relevant parameters to achieve efficient and versatile light manipulation. In particular, we show that the overall structure, acting as a hybrid plasmonic-photonics meta-surface, can be engineered in order to maximize its linear and circular dichroic behavior at optical frequencies.

  20. Number-conserving linear response study of low-velocity ion stopping in a collisional magnetized classical plasma

    Directory of Open Access Journals (Sweden)

    Nersisyan Hrachya B.

    2013-11-01

    Full Text Available The low-velocity stopping power of ions in a magnetized collisional plasma is studied through the linear response theory. The collisions are taken into account through a number-conserving relaxation time approximation. One of the major objectives of this study is to compare and contrast our theoretical results with those obtained through a diffusion coefficient formulation based on Dufty-Berkovsky relation.

  1. Evaluation of linearity of response and angular dependence of an ionization chamber for dosimetry in computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Perini, Ana P.; Neves, Lucio P.; Xavier, Marcos; Caldas, Linda V.E., E-mail: mxavier@ipen.b, E-mail: lcaldas@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Khoury, Helen J., E-mail: khoury@ufpe.b [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear

    2011-07-01

    In this paper a pencil-type ionization chamber designed and manufactured at Instituto de Pesquisas Energeticas e Nucleares was evaluated for dosimetric applications in computed tomography beams. To evaluate the performance of this chamber two tests were undertaken: linearity of response and angular dependence. The results obtained in these tests showed good results, within the international recommendations. Moreover, this homemade ionization chamber is easy to manufacture, of low cost and efficient. (author)

  2. The stability of a predator-prey system with linear mass-action functional response perturbed by white noise.

    Science.gov (United States)

    Zhang, Qiumei; Wen, Xiangdan; Jiang, Daqing; Liu, Zhenwen

    The present paper deals with the problem of an ecoepidemiological model with linear mass-action functional response perturbed by white noise. The essential mathematical features are analyzed with the help of the stochastic stability, its long time behavior around the equilibrium of deterministic ecoepidemiological model, and the stochastic asymptotic stability by Lyapunov analysis methods. Numerical simulations for a hypothetical set of parameter values are presented to illustrate the analytical findings.

  3. Linear trend and climate response of five-needle pines in the western United States related to treeline proximity

    Energy Technology Data Exchange (ETDEWEB)

    Kipfmueller, K.F. [Minnesota Univ., Minneapolis, MN (United States). Dept. of Geography; Salzer, M.W. [Arizona Univ., Tucson, AZ (United States). Laboratory of Tree-Ring Research

    2010-01-15

    This study investigated sixty-six 5-needle pine growth chronologies from 1896 to their end years in order to identify potential patterns related to linear trends in ring width. Individual chronology responses to climate were also evaluated by comparing the chronologies with seasonal temperature and precipitation data from 1896 to the present date. Chronologies exhibiting similar patterns of climate response were grouped in order to examine the role of treeline proximity on climate-growth relationships. Ring width measurements for pine sites located in the western United States were obtained from the International Tree Ring Data Bank. Growth indices were compared among all sites in order to assess the relative strength of common signals with increasing distance. Pearson correlations were used to calculate linear trends for each chronology. A cluster analysis of climate response patterns indicated that most chronologies positively associated with temperatures were located near upper treeline and contained significant positive linear trends. The study suggested that 5-needle pine treeline chronologies may be used as predictors in temperature reconstructions. However, care must be taken to determine that collection sites have not been impacted by disturbances such as fire or insect outbreaks. 35 refs., 2 tabs., 5 figs.

  4. Ecological versus case-control studies for testing a linear-no threshold dose-response relationship.

    Science.gov (United States)

    Cohen, B L

    1990-09-01

    The two basic problems with ecological studies are (A) individuals studied are not necessarily the individuals who are at risk, and (B) they are very vulnerable to confounding factors. It is shown that where the study is designed to test a linear-no threshold dose-response theory, (A) does not apply. Where the ecological study deals with the average dose and response in a large number of US counties, the available data and computer capability for reducing effects of confounders are so powerful that (B) may be no more important for the ecological than for a case-control study. The migration problem is treated and found to be relatively unimportant.

  5. Open-loop frequency response analysis of a wind turbine using a high-order linear aeroelastic model

    DEFF Research Database (Denmark)

    Sønderby, Ivan Bergquist; Hansen, Morten Hartvig

    2014-01-01

    Wind turbine controllers are commonly designed on the basis of low-order linear models to capture the aeroelastic wind turbine response due to control actions and disturbances. This paper characterizes the aeroelastic wind turbine dynamics that influence the open-loop frequency response from gene......-minimum phase zeros below the frequency of the first drivetrain mode. To correctly predict the non-minimum phase zeros, it is essential to include lateral tower and blade flap degrees of freedom. Copyright © 2013 John Wiley & Sons, Ltd....

  6. Precision Interval Estimation of the Response Surface by Means of an Integrated Algorithm of Neural Network and Linear Regression

    Science.gov (United States)

    Lo, Ching F.

    1999-01-01

    The integration of Radial Basis Function Networks and Back Propagation Neural Networks with the Multiple Linear Regression has been accomplished to map nonlinear response surfaces over a wide range of independent variables in the process of the Modem Design of Experiments. The integrated method is capable to estimate the precision intervals including confidence and predicted intervals. The power of the innovative method has been demonstrated by applying to a set of wind tunnel test data in construction of response surface and estimation of precision interval.

  7. Comparison of the dynamic response of the ACS and SLS models for linear viscoelasticity

    Energy Technology Data Exchange (ETDEWEB)

    Pound, M.J.; Chin, R.C.Y.; Hedstrom, G.W.

    1984-01-01

    Using asymptotic analysis and numerical computation, the authors compare the behavior of the three-parameter viscoelastic model proposed by Achenbach and Chao (ACS) with that of the Standard Linear Solid (SLS) in one-dimensional wave propagation. Their study shows that the models behave very similarly in both the near and far fields and that the much simpler form of the fundamental solution for the Achenbach-Chao model may make it preferable in many applications. 8 references, 3 figures, 1 table.

  8. A dose-response curve for biodosimetry from a 6 MV electron linear accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Lemos-Pinto, M.M.P.; Cadena, M.; Santos, N.; Fernandes, T.S.; Borges, E.; Amaral, A., E-mail: marcelazoo@yahoo.com.br [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Departamento de Energia Nuclear

    2015-10-15

    Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET) and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA). Two software programs, CABAS (Chromosomal Aberration Calculation Software) and Dose Estimate, were used to generate the curve. The two software programs are discussed; the results obtained were compared with each other and with other published low LET radiation curves. Both software programs resulted in identical linear and quadratic terms for the curve presented here, which was in good agreement with published curves for similar radiation quality and dose rates. (author)

  9. A dose-response curve for biodosimetry from a 6 MV electron linear accelerator

    Science.gov (United States)

    Lemos-Pinto, M.M.P.; Cadena, M.; Santos, N.; Fernandes, T.S.; Borges, E.; Amaral, A.

    2015-01-01

    Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET) and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA). Two software programs, CABAS (Chromosomal Aberration Calculation Software) and Dose Estimate, were used to generate the curve. The two software programs are discussed; the results obtained were compared with each other and with other published low LET radiation curves. Both software programs resulted in identical linear and quadratic terms for the curve presented here, which was in good agreement with published curves for similar radiation quality and dose rates. PMID:26445334

  10. A dose-response curve for biodosimetry from a 6 MV electron linear accelerator.

    Science.gov (United States)

    Lemos-Pinto, M M P; Cadena, M; Santos, N; Fernandes, T S; Borges, E; Amaral, A

    2015-10-01

    Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET) and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA). Two software programs, CABAS (Chromosomal Aberration Calculation Software) and Dose Estimate, were used to generate the curve. The two software programs are discussed; the results obtained were compared with each other and with other published low LET radiation curves. Both software programs resulted in identical linear and quadratic terms for the curve presented here, which was in good agreement with published curves for similar radiation quality and dose rates.

  11. A dose-response curve for biodosimetry from a 6 MV electron linear accelerator

    Directory of Open Access Journals (Sweden)

    M.M.P. Lemos-Pinto

    2015-01-01

    Full Text Available Biological dosimetry (biodosimetry is based on the investigation of radiation-induced biological effects (biomarkers, mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA. Two software programs, CABAS (Chromosomal Aberration Calculation Software and Dose Estimate, were used to generate the curve. The two software programs are discussed; the results obtained were compared with each other and with other published low LET radiation curves. Both software programs resulted in identical linear and quadratic terms for the curve presented here, which was in good agreement with published curves for similar radiation quality and dose rates.

  12. No Evidence for a Low Linear Energy Transfer Adaptive Response in Irradiated RKO Cells

    Energy Technology Data Exchange (ETDEWEB)

    Sowa, Marianne B.; Goetz, Wilfried; Baulch, Janet E.; Lewis, Adam J.; Morgan, William F.

    2011-01-06

    It has become increasingly evident from reports in the literature that there are many confounding factors that are capable of modulating radiation induced non-targeted responses such as the bystander effect and the adaptive response. In this paper we examine recent data that suggest that the observation of non-targeted responses may not be universally observable for differing radiation qualities. We have conducted a study of the adaptive response following low LET exposures for human colon carcinoma cells and failed to observe adaption for the endpoints of clonogenic survival or micronucleus formation.

  13. A new method for predicting response in complex linear systems. II. [under random or deterministic steady state excitation

    Science.gov (United States)

    Bogdanoff, J. L.; Kayser, K.; Krieger, W.

    1977-01-01

    The paper describes convergence and response studies in the low frequency range of complex systems, particularly with low values of damping of different distributions, and reports on the modification of the relaxation procedure required under these conditions. A new method is presented for response estimation in complex lumped parameter linear systems under random or deterministic steady state excitation. The essence of the method is the use of relaxation procedures with a suitable error function to find the estimated response; natural frequencies and normal modes are not computed. For a 45 degree of freedom system, and two relaxation procedures, convergence studies and frequency response estimates were performed. The low frequency studies are considered in the framework of earlier studies (Kayser and Bogdanoff, 1975) involving the mid to high frequency range.

  14. Real-time, real-space implementation of the linear response time-dependent density-functional theory

    Science.gov (United States)

    Yabana, K.; Nakatsukasa, T.; Iwata, J.-I.; Bertsch, G. F.

    We review our methods to calculate optical response of molecules in the linear response time-dependent density-functional theory. Three distinct formalisms which are implemented in the three-dimensional grid representation are explained in detail. They are the real-time method solving the time-dependent Kohn-Sham equation in the time domain, the modified Sternheimer method which calculates the response to an external field of fixed frequency, and the matrix eigenvalue approach. We also illustrate treatments of the scattering boundary condition, needed to accurately describe photoionization processes. Finally, we show how the real-time formalism for molecules can be used to determine the response of infinite periodic systems.

  15. Real-time, real-space implementation of the linear response time-dependent density-functional theory

    Energy Technology Data Exchange (ETDEWEB)

    Yabana, K.; Nakatsukasa, T. [Center for Computational Sciences, University of Tsukuba, Tsukuba 305-8571 (Japan); Institute of Physics, University of Tsukuba, Tsukuba 305-8571 (Japan); Iwata, J.I. [Center for Computational Sciences, University of Tsukuba, Tsukuba 305-8571 (Japan); Bertsch, G.F. [Department of Physics and Institute for Nuclear Theory, University of Washington, Seattle 98195 (United States)

    2006-04-15

    We review our methods to calculate optical response of molecules in the linear response time-dependent density-functional theory. Three distinct formalisms which are implemented in the three-dimensional grid representation are explained in detail. They are the real-time method solving the time-dependent Kohn-Sham equation in the time domain, the modified Sternheimer method which calculates the response to an external field of fixed frequency, and the matrix eigenvalue approach. We also illustrate treatments of the scattering boundary condition, needed to accurately describe photoionization processes. Finally, we show how the real-time formalism for molecules can be used to determine the response of infinite periodic systems. (copyright 2006 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  16. Linear regression

    CERN Document Server

    Olive, David J

    2017-01-01

    This text covers both multiple linear regression and some experimental design models. The text uses the response plot to visualize the model and to detect outliers, does not assume that the error distribution has a known parametric distribution, develops prediction intervals that work when the error distribution is unknown, suggests bootstrap hypothesis tests that may be useful for inference after variable selection, and develops prediction regions and large sample theory for the multivariate linear regression model that has m response variables. A relationship between multivariate prediction regions and confidence regions provides a simple way to bootstrap confidence regions. These confidence regions often provide a practical method for testing hypotheses. There is also a chapter on generalized linear models and generalized additive models. There are many R functions to produce response and residual plots, to simulate prediction intervals and hypothesis tests, to detect outliers, and to choose response trans...

  17. The modernization paradigm based on monistic multi-linear theory: a response to some comments

    Institute of Scientific and Technical Information of China (English)

    Dong Zhenghua

    2006-01-01

    Long before 1979,Chinese historical research had been dominated by the theory of "the Five Modes of Production",according to which the whole Chinese history as well as the other parts of the world had been developed from the first MOD to the last one by one.The modernization theories prevailed during the 1950s and the 1960s,bringing about another uni-linear model of historical changes.For example,W.W.Rostow designed a five-stage process as a universal frame work of economic development,based on which each society could find its position in this uni-line.The task of the less developed societies is just to introduce modernity from the modernized societies so that they can make some developments.Thus modernization is a uni-direction movement as well as a uni-linear process.After 1979,modernization as a new paradigm has been accepted by an increasing number of Chinese historians.The increasing depth and breadth of the academic researches have encouraged such an acceptance,but,admittedly,as a new conceptual system that corresponded to the historic breakthrough and the new direction towards modernization in China.This acceptance also showed the "crisis of paradigm",that is,the contradiction between the new themes and the old ones that had dominated Chinese humanities and social sciences.The modernization paradigm based on monistic multi-linear theory considers modernization as a unique breakthrough in history,a great transformation around the whole world,and a historical process that does not have a given ultimate aim and value but different models and routes.The monistic multi-finear theory on historical development is open and all-embracing in historical studies.A variety of historical paradigms is favorable to prosperity of Chinese history.

  18. Non-linear analysis of body responses to functional electrical stimulation on hemiplegic subjects.

    Science.gov (United States)

    Yu, W W; Acharya, U R; Lim, T C; Low, H W

    2009-08-01

    Functional electrical stimulation (FES) is a method of applying low-level electrical currents to restore or improve body functions lost through nervous system impairment. FES is applied to peripheral nerves that control specific muscles or muscle groups. Application of advanced signal computing techniques to the medical field has helped to achieve practical solutions to the health care problems accurately. The physiological signals are essentially non-stationary and may contain indicators of current disease, or even warnings about impending diseases. These indicators may be present at all times or may occur at random on the timescale. However, to study and pinpoint these subtle changes in the voluminous data collected over several hours is tedious. These signals, e.g. walking-related accelerometer signals, are not simply linear and involve non-linear contributions. Hence, non-linear signal-processing methods may be useful to extract the hidden complexities of the signal and to aid physicians in their diagnosis. In this work, a young female subject with major neuromuscular dysfunction of the left lower limb, which resulted in an asymmetric hemiplegic gait, participated in a series of FES-assisted walking experiments. Two three-axis accelerometers were attached to her left and right ankles and their corresponding signals were recorded during FES-assisted walking. The accelerometer signals were studied in three directions using the Hurst exponent H, the fractal dimension (FD), the phase space plot, and recurrence plots (RPs). The results showed that the H and FD values increase with increasing FES, indicating more synchronized variability due to FES for the left leg (paralysed leg). However, the variation in the normal right leg is more chaotic on FES.

  19. Enhanced linear and nonlinear optical phase response of AlGaAs microring resonators.

    Science.gov (United States)

    Heebner, John E; Lepeshkin, Nick N; Schweinsberg, Aaron; Wicks, G W; Boyd, Robert W; Grover, Rohit; Ho, P T

    2004-04-01

    We have constructed and characterized several optical microring resonators with scale sizes of the order of 10 microm. These devices are intended to serve as building blocks for engineerable linear and nonlinear photonic media. Light is guided vertically by an epitaxially grown structure and transversely by deeply etched air-clad sidewalls. We report on the spectral phase transfer characteristics of such resonators. We also report the observation of a pi-rad Kerr nonlinear phase shift accumulated in a single compact ring resonator evidenced by all-optical switching between output ports of a resonator-enhanced Mach-Zehnder interferometer.

  20. Atypical response to treatment in linear IgA bullous dermatosis of childhood: Revision of literature.

    Science.gov (United States)

    Moleiro, Susana; Santos, Vera; Calha, Manuela; Pessoa, Graça

    2011-06-15

    A three-year-old boy presented with 2 months of worsening skin lesions characterized by multiple clear vesicles and bullae. The histopathological and immunohistochemical examinations revealed changes consistent with linear IgA bullous dermatosis of childhood. Treatment with dapsone and prednisolone resulted in gradual clinical improvement. However, within a week of therapy he presented with diabetic ketoacidosis, the onset of type I diabetes mellitus. Since then, keeping this child asymptomatic has been a challenge. This case emphasizes the importance of close monitoring of patients taking systemic corticosteroids; the coexistence of other immune mediated conditions may influence the success of treatment.

  1. Spatially variable water table recharge and the hillslope hydrologic response: Analytical solutions to the linearized hillslope Boussinesq equation

    Science.gov (United States)

    Dralle, David N.; Boisramé, Gabrielle F. S.; Thompson, Sally E.

    2014-11-01

    The linearized hillslope Boussinesq equation, introduced by Brutsaert (1994), describes the dynamics of saturated, subsurface flow from hillslopes with shallow, unconfined aquifers. In this paper, we use a new analytical technique to solve the linearized hillslope Boussinesq equation to predict water table dynamics and hillslope discharge to channels. The new solutions extend previous analytical treatments of the linearized hillslope Boussinesq equation to account for the impact of spatiotemporal heterogeneity in water table recharge. The results indicate that the spatial character of recharge may significantly alter both steady state subsurface storage characteristics and the transient hillslope hydrologic response, depending strongly on similarity measures of controls on the subsurface flow dynamics. Additionally, we derive new analytical solutions for the linearized hillslope-storage Boussinesq equation and explore the interaction effects of recharge structure and hillslope morphology on water storage and base flow recession characteristics. A theoretical recession analysis, for example, demonstrates that decreasing the relative amount of downslope recharge has a similar effect as increasing hillslope convergence. In general, the theory suggests that recharge heterogeneity can serve to diminish or enhance the hydrologic impacts of hillslope morphology.

  2. Non-linear Membrane Properties in Entorhinal Cortical Stellate Cells Reduce Modulation of Input-Output Responses by Voltage Fluctuations.

    Science.gov (United States)

    Fernandez, Fernando R; Malerba, Paola; White, John A

    2015-04-01

    The presence of voltage fluctuations arising from synaptic activity is a critical component in models of gain control, neuronal output gating, and spike rate coding. The degree to which individual neuronal input-output functions are modulated by voltage fluctuations, however, is not well established across different cortical areas. Additionally, the extent and mechanisms of input-output modulation through fluctuations have been explored largely in simplified models of spike generation, and with limited consideration for the role of non-linear and voltage-dependent membrane properties. To address these issues, we studied fluctuation-based modulation of input-output responses in medial entorhinal cortical (MEC) stellate cells of rats, which express strong sub-threshold non-linear membrane properties. Using in vitro recordings, dynamic clamp and modeling, we show that the modulation of input-output responses by random voltage fluctuations in stellate cells is significantly limited. In stellate cells, a voltage-dependent increase in membrane resistance at sub-threshold voltages mediated by Na+ conductance activation limits the ability of fluctuations to elicit spikes. Similarly, in exponential leaky integrate-and-fire models using a shallow voltage-dependence for the exponential term that matches stellate cell membrane properties, a low degree of fluctuation-based modulation of input-output responses can be attained. These results demonstrate that fluctuation-based modulation of input-output responses is not a universal feature of neurons and can be significantly limited by subthreshold voltage-gated conductances.

  3. Nonlinear optics of complex plasmonic structures: linear and third-order optical response of orthogonally coupled metallic nanoantennas

    Science.gov (United States)

    Metzger, Bernd; Hentschel, Mario; Nesterov, Maxim; Schumacher, Thorsten; Lippitz, Markus; Giessen, Harald

    2016-04-01

    We investigate the polarization-resolved linear and third-order optical response of plasmonic nanostructure arrays that consist of orthogonally coupled gold nanoantennas. By rotating the incident light polarization direction, either one of the two eigenmodes of the coupled system or a superposition of the eigenmodes can be excited. We find that when an eigenmode is driven by the external light field, the generated third-harmonic signals exhibit the same polarization direction as the fundamental field. In contrast, when a superposition of the two eigenmodes is excited, third-harmonic can efficiently be radiated at the perpendicular polarization direction. Furthermore, the interference of the coherent third-harmonic signals radiated from both nanorods proves that the phase between the two plasmonic oscillators changes in the third-harmonic signal over 3π when the laser is spectrally tuned over the resonance, rather than over π as in the case of the fundamental field. Finally, almost all details of the linear and the nonlinear spectra can be described by an anharmonic coupled oscillator model, which we discuss in detail and which provides deep insight into the linear and the nonlinear optical response of coupled plasmonic nanoantennas.

  4. Subharmonic Response of Linear Vibroimpact System with Fractional Derivative Damping to a Randomly Disrobed Periodic Excitation

    Directory of Open Access Journals (Sweden)

    Haiwu Rong

    2015-01-01

    Full Text Available The subharmonic response of single-degree-of-freedom vibroimpact oscillator with fractional derivative damping and one-sided barrier under narrow-band random excitation is investigated. With the help of a special Zhuravlev transformation, the system is reduced to one without impacts, thereby permitting the applications of asymptotic averaging over the period for slowly varying random process. The analytical expression of the response amplitude is obtained in the case without random disorder, while only the approximate analytical expressions for the steady-state moments of the response amplitude are obtained in the case with random disorder. The effects of the fractional order derivative term, damping term, random disorder, and the coefficient of restitution and other system parameters on the system response are discussed. Theoretical analyses and numerical simulations show that fractional derivative makes both the system damping and stiffness coefficients increase, such that it changes the system parameters region at which the response amplitude reaches the maximum. The system energy loss in collision is equivalent to increasing the damping coefficient of the system. System response amplitude will increase when the excitation frequency is close to the resonant frequency and will decay rapidly when the excitation frequency gradually deviates from the resonance frequency.

  5. Complex motor task associated with non-linear BOLD responses in cerebro-cortical areas and cerebellum.

    Science.gov (United States)

    Alahmadi, Adnan A S; Samson, Rebecca S; Gasston, David; Pardini, Matteo; Friston, Karl J; D'Angelo, Egidio; Toosy, Ahmed T; Wheeler-Kingshott, Claudia A M

    2016-06-01

    Previous studies have used fMRI to address the relationship between grip force (GF) applied to an object and BOLD response. However, whilst the majority of these studies showed a linear relationship between GF and neural activity in the contralateral M1 and ipsilateral cerebellum, animal studies have suggested the presence of non-linear components in the GF-neural activity relationship. Here, we present a methodology for assessing non-linearities in the BOLD response to different GF levels, within primary motor as well as sensory and cognitive areas and the cerebellum. To be sensitive to complex forms, we designed a feasible grip task with five GF targets using an event-related visually guided paradigm and studied a cohort of 13 healthy volunteers. Polynomial functions of increasing order were fitted to the data. (1) activated motor areas irrespective of GF; (2) positive higher-order responses in and outside M1, involving premotor, sensory and visual areas and cerebellum; (3) negative correlations with GF, predominantly involving the visual domain. Overall, our results suggest that there are physiologically consistent behaviour patterns in cerebral and cerebellar cortices; for example, we observed the presence of a second-order effect in sensorimotor areas, consistent with an optimum metabolic response at intermediate GF levels, while higher-order behaviour was found in associative and cognitive areas. At higher GF levels, sensory-related cortical areas showed reduced activation, interpretable as a redistribution of the neural activity for more demanding tasks. These results have the potential of opening new avenues for investigating pathological mechanisms of neurological diseases.

  6. Real-time Needle Steering in Response to Rolling Vein Deformation by a 9-DOF Image-Guided Autonomous Venipuncture Robot.

    Science.gov (United States)

    Chen, Alvin I; Balter, Max L; Maguire, Timothy J; Yarmush, Martin L

    2015-01-01

    Venipuncture is the most common invasive medical procedure performed in the United States and the number one cause of hospital injury. Failure rates are particularly high in pediatric and elderly patients, whose veins tend to deform, move, or roll as the needle is introduced. To improve venipuncture accuracy in challenging patient populations, we have developed a portable device that autonomously servos a needle into a suitable vein under image guidance. The device operates in real time, combining near-infrared and ultrasound imaging, computer vision software, and a 9 degrees-of-freedom robot that servos the needle. In this paper, we present the kinematic and mechanical design of the latest generation robot. We then investigate in silico and in vitro the mechanics of vessel rolling and deformation in response to needle insertions performed by the robot. Finally, we demonstrate how the robot can make real-time adjustments under ultrasound image guidance to compensate for subtle vessel motions during venipuncture.

  7. Pancreatic beta cell function increases in a linear dose-response manner following exercise training in adults with prediabetes

    DEFF Research Database (Denmark)

    Malin, Steven K; Solomon, Thomas; Blaszczak, Alecia

    2013-01-01

    composition (dual-energy x-ray absorptiometry and computed tomography) were also measured before and after the intervention. Exercise dose was computed using VO2-heart rate derived linear-regression equations. Subjects expended 474.5±8.8 kcal/session (2372.5±44.1 kcal/week) during the intervention, and lost...... ~8% body weight. Exercise increased first and second phase DI (P2000 kcal/week) are necessary to enhance beta-cell function in adults with poor insulin secretion capacity.......While some studies suggest that a linear dose-response relationship exists between exercise and insulin sensitivity, the exercise dose required to enhance pancreatic beta-cell function is unknown. Thirty-five older, obese adults with prediabetes underwent a progressive 12-week supervised exercise...

  8. All-Printed Thin-Film Transistor Based on Purified Single-Walled Carbon Nanotubes with Linear Response

    Directory of Open Access Journals (Sweden)

    Guiru Gu

    2011-01-01

    Full Text Available We report an all-printed thin-film transistor (TFT on a polyimide substrate with linear transconductance response. The TFT is based on our purified single-walled carbon nanotube (SWCNT solution that is primarily consists of semiconducting carbon nanotubes (CNTs with low metal impurities. The all-printed TFT exhibits a high ON/OFF ratio of around 103 and bias-independent transconductance over a certain gate bias range. Such bias-independent transconductance property is different from that of conventional metal-oxide-semiconductor field-effect transistors (MOSFETs due to the special band structure and the one-dimensional (1D quantum confined density of state (DOS of CNTs. The bias-independent transconductance promises modulation linearity for analog electronics.

  9. Aging and linear response in the Hébraud-Lequeux model for amorphous rheology

    Science.gov (United States)

    Sollich, Peter; Olivier, Julien; Bresch, Didier

    2017-04-01

    We analyse the aging dynamics of the Hébraud-Lequeux model, a self-consistent stochastic model for the evolution of local stress in an amorphous material. We show that the model exhibits initial-condition dependent freezing: the stress diffusion constant decays with time as D˜ 1/{{t}2} during aging so that the cumulative amount of memory that can be erased, which is given by the time integral of D(t), is finite. Accordingly the shear stress relaxation function, which we determine in the long-time regime, only decays to a plateau and becomes progressively elastic as the system ages. The frequency-dependent shear modulus exhibits a corresponding overall decay of the dissipative part with system age, while the characteristic relaxation times scale linearly with age as expected.

  10. An ultra wide dynamic range CMOS image sensor with a linear response

    Science.gov (United States)

    Park, Jong Ho; Mase, Mitsuhito; Kawahito, Shoji; Sasaki, Masaaki; Wakamori, Yasuo; Ohta, Yukihiro

    2006-02-01

    An ultra wide dynamic range (WDR) CMOS image sensor (CIS) and the details of evaluation are presented. The proposed signal readout technique of extremely short accumulation (ESA) enables the dynamic range of image sensor to be expanded up to 146dB. Including the ESA signals, total of 4 different accumulation time signals are read out in one frame period based on burst readout technique. To achieve the high-speed signal readout required for the multiple exposure signals, column parallel A/D converters are integrated at the upper and lower sides of pixel arrays. The improved 12-bits cyclic ADCs with a built-in correlated double sampling (CDS) circuit has the differential non-linearity (DNL) of +/-0.3LSB.

  11. Characterization of Photon-Counting Detector Responsivity for Non-Linear Two-Photon Absorption Process

    Science.gov (United States)

    Sburlan, S. E.; Farr, W. H.

    2011-01-01

    Sub-band absorption at 1550 nm has been demonstrated and characterized on silicon Geiger mode detectors which normally would be expected to have no response at this wavelength. We compare responsivity measurements to singlephoton absorption for wavelengths slightly above the bandgap wavelength of silicon (approx. 1100 microns). One application for this low efficiency sub-band absorption is in deep space optical communication systems where it is desirable to track a 1030 nm uplink beacon on the same flight terminal detector array that monitors a 1550 nm downlink signal for pointingcontrol. The currently observed absorption at 1550 nm provides 60-70 dB of isolation compared to the response at 1064 nm, which is desirable to avoid saturation of the detector by scattered light from the downlink laser.

  12. Linear Response of Field-Aligned Currents to the Interplanetary Electric Field

    DEFF Research Database (Denmark)

    Weimer, D. R.; R. Edwards, T.; Olsen, Nils

    2017-01-01

    Many studies that have shown that the ionospheric, polar cap electric potentials (PCEP) exhibit a “saturation” behavior in response to the level of the driving by the solar wind. As the magnitude of the interplanetary magnetic field (IMF) and electric field (IEF) increase, the PCEP response...... of the field-aligned currents (FAC) with the solar wind/magnetosphere/ionosphere system has a role. As the FAC are more difficult to measure, their behavior in response to the level of the IEF has not been investigated as thoroughly. In order to resolve the question of whether or not the FAC also exhibit...... saturation, we have processed the magnetic field measurements from the Ørsted, CHAMP, and Swarm missions, spanning more than a decade. As the amount of current in each region needs to be known, a new technique is used to separate and sum the current by region, widely known as R0, R1, and R2. These totals...

  13. Characterization of Photon-Counting Detector Responsivity for Non-Linear Two-Photon Absorption Process

    Science.gov (United States)

    Sburlan, S. E.; Farr, W. H.

    2011-01-01

    Sub-band absorption at 1550 nm has been demonstrated and characterized on silicon Geiger mode detectors which normally would be expected to have no response at this wavelength. We compare responsivity measurements to singlephoton absorption for wavelengths slightly above the bandgap wavelength of silicon (approx. 1100 microns). One application for this low efficiency sub-band absorption is in deep space optical communication systems where it is desirable to track a 1030 nm uplink beacon on the same flight terminal detector array that monitors a 1550 nm downlink signal for pointingcontrol. The currently observed absorption at 1550 nm provides 60-70 dB of isolation compared to the response at 1064 nm, which is desirable to avoid saturation of the detector by scattered light from the downlink laser.

  14. Synthesis, characterization and non-linear optical response of organophilic carbon dots

    KAUST Repository

    Bourlinos, Athanasios B.

    2013-09-01

    For the first time ever we report the nonlinear optical (NLO) properties of carbon dots (C-dots). The C-dots for these experiments were synthesized by mild pyrolysis of lauryl gallate. The resulting C-dots bear lauryl chains and, hence, are highly dispersible in polar organic solvents, like chloroform. Dispersions in CHCl3 show significant NLO response. Specifically, the C-dots show negative nonlinear absorption coefficient and negative nonlinear refraction. Using suspensions with different concentrations these parameters are quantified and compared to those of fullerene a well-known carbon molecule with proven NLO response. © 2013 Elsevier Ltd. All rights reserved.

  15. Deformable Simplicial Complexes

    DEFF Research Database (Denmark)

    Misztal, Marek Krzysztof

    In this dissertation we present a novel method for deformable interface tracking in 2D and 3D|deformable simplicial complexes (DSC). Deformable interfaces are used in several applications, such as fluid simulation, image analysis, reconstruction or structural optimization. In the DSC method......, the interface (curve in 2D; surface in 3D) is represented explicitly as a piecewise linear curve or surface. However, the domain is also subject to discretization: triangulation in 2D; tetrahedralization in 3D. This way, the interface can be alternatively represented as a set of edges/triangles separating...... demonstrate those strengths in several applications. In particular, a novel, DSC-based fluid dynamics solver has been developed during the PhD project. A special feature of this solver is that due to the fact that DSC maintains an explicit interface representation, surface tension is more easily dealt with...

  16. Numerical simulations of deformation and movement of blocks within North China in response to 1976 Tangshan earthquake

    Institute of Scientific and Technical Information of China (English)

    白武明; 林邦慧; 陈祖安

    2003-01-01

    Using methods of discontinuous deformation analysis and finite element (DDA+FEM), this paper simulates dynamic processes of the Tangshan earthquake of 1976, which occurred in the northern North China where its internal blocks apparently interacted. Studies focus upon both the movement and deformation of the blocks, in particular, the Ordos block, and variations of stress states on the boundary faults. The Tangshan earthquake was composed of three events: slipping motions of NNE-striking major fault, NE-striking fault near the northeastern end of the NNE-striking fault, and NW-striking fault on the southeastern side of the NNE-striking fault. Compared with previous studies, our model yields a result that is more agreeable with the configuration of aftershock distributions. A number of data are presented, such as the principle stress field during the earthquake, contours of the maximum shear stress, the strike-slip deformation between blocks near the earthquake focus, time-dependent variations of slips of earthquake-triggered faulting, the maximum slip distance, and stress drops. These results are in accord with the earthquake source mechanism, basic parameters from earthquake wave study, macro-isoseismic line, observed horizontal displacement vectors, etc. The Tangshan earthquake exerted different influences on the adjacent blocks and boundary faults between them, thus resulting in differential movement and deformation. The Ordos block seems to have experienced the small-scale counterclockwise rotation and deformation, but its northeast part, bounded on the east by the Taihangshan and on the north by the Yanshan and Yinshan belts, underwent relatively stronger deformation. The Tangshan earthquake also changed the stress state of boundary faults of the North China, leading to an increase in shear stress and a decrease in normal stress in the NW-trending Zhangjiakou-Penglai fault through Tangshan City and the northern border faults of the Ordos block, and therefore

  17. Practical methods for dealing with 'not applicable' item responses in the AMC Linear Disability Score project

    NARCIS (Netherlands)

    Holman, Rebecca; Glas, Cornelis A.W.; Lindeboom, Robert; Zwinderman, Aeilko H.; de Haan, Rob J.

    2004-01-01

    Background: Whenever questionnaires are used to collect data on constructs, such as functional status or health related quality of life, it is unlikely that all respondents will respond to all items. This paper examines ways of dealing with responses in a 'not applicable' category to items included

  18. Response analysis of a laminar premixed M-flame to flow perturbations using a linearized compressible Navier-Stokes solver

    Energy Technology Data Exchange (ETDEWEB)

    Blanchard, M., E-mail: mathieu.blanchard@ladhyx.polytechnique.fr [LadHyX, CNRS and Ecole Polytechnique, 91128 Palaiseau (France); Schuller, T. [CNRS, UPR 288, Laboratoire d’Energétique Moléculaire et Macroscopique Combustion (EM2C), Grande Voie des Vignes, 92290 Châtenay-Malabry (France); Centrale-Supélec, Grande Voie des Vignes, 92290 Châtenay-Malabry (France); Sipp, D. [ONERA-DAFE, 8 rue des Vertugadins, 92190 Meudon (France); Schmid, P. J. [Department of Mathematics, Imperial College London, London SW7 2AZ (United Kingdom)

    2015-04-15

    The response of a laminar premixed methane-air flame subjected to flow perturbations around a steady state is examined experimentally and using a linearized compressible Navier-Stokes solver with a one-step chemistry mechanism to describe combustion. The unperturbed flame takes an M-shape stabilized both by a central bluff body and by the external rim of a cylindrical nozzle. This base flow is computed by a nonlinear direct simulation of the steady reacting flow, and the flame topology is shown to qualitatively correspond to experiments conducted under comparable conditions. The flame is then subjected to acoustic disturbances produced at different locations in the numerical domain, and its response is examined using the linearized solver. This linear numerical model then allows the componentwise investigation of the effects of flow disturbances on unsteady combustion and the feedback from the flame on the unsteady flow field. It is shown that a wrinkled reaction layer produces hydrodynamic disturbances in the fresh reactant flow field that superimpose on the acoustic field. This phenomenon, observed in several experiments, is fully interpreted here. The additional perturbations convected by the mean flow stem from the feedback of the perturbed flame sheet dynamics onto the flow field by a mechanism similar to that of a perturbed vortex sheet. The different regimes where this mechanism prevails are investigated by examining the phase and group velocities of flow disturbances along an axis oriented along the main direction of the flow in the fresh reactant flow field. It is shown that this mechanism dominates the low-frequency response of the wrinkled shape taken by the flame and, in particular, that it fully determines the dynamics of the flame tip from where the bulk of noise is radiated.

  19. Local control theory using trajectory surface hopping and linear-response time-dependent density functional theory.

    Science.gov (United States)

    Curchod, Basile F E; Penfold, Thomas J; Rothlisberger, Ursula; Tavernelli, Ivano

    2013-01-01

    The implementation of local control theory using nonadiabatic molecular dynamics within the framework of linear-response time-dependent density functional theory is discussed. The method is applied to study the photoexcitation of lithium fluoride, for which we demonstrate that this approach can efficiently generate a pulse, on-the-fly, able to control the population transfer between two selected electronic states. Analysis of the computed control pulse yields insights into the photophysics of the process identifying the relevant frequencies associated to the curvature of the initial and final state potential energy curves and their energy differences. The limitations inherent to the use of the trajectory surface hopping approach are also discussed.

  20. Non-linear optical properties of molecules in heterogeneous environments: a quadratic density functional/molecular mechanics response theory.

    Science.gov (United States)

    Rinkevicius, Zilvinas; Li, Xin; Sandberg, Jaime A R; Ågren, Hans

    2014-05-21

    We generalize a density functional theory/molecular mechanics approach for heterogeneous environments with an implementation of quadratic response theory. The updated methodology allows us to address a variety of non-linear optical, magnetic and mixed properties of molecular species in complex environments, such as combined metallic, solvent and confined organic environments. Illustrating calculations of para-nitroaniline on gold surfaces and in solution reveals a number of aspects that come into play when analyzing second harmonic generation of such systems--such as surface charge flow, coupled surface-solvent dynamics and induced geometric and electronic structure effects of the adsorbate. Some ramifications of the methodology for applied studies are discussed.

  1. Dynamical Linear Response of TDDFT with LDA+U Functional: Strongly Hybridized Frenkel Excitons in NiO

    Energy Technology Data Exchange (ETDEWEB)

    Lee, C.C.; Ku, W.; Hsueh, H.C.

    2010-08-30

    Within the framework of time-dependent density-functional theory (TDDFT), we derive the dynamical linear response of local-density approximation plus U functional and benchmark it on NiO, a prototypical Mott insulator. Formulated using real-space Wannier functions, our computationally inexpensive framework gives detailed insights into the formation of tightly bound Frenkel excitons with reasonable accuracy. Specifically, a strong hybridization of multiple excitons is found to significantly modify the exciton properties. Furthermore, our study exposes a significant generic limitation of adiabatic approximation in TDDFT with hybrid functionals and in existing Bethe-Salpeter-equation approaches, advocating the necessity of strongly energy-dependent kernels in future development.

  2. Contracture deformity

    Science.gov (United States)

    Deformity - contracture ... Contracture can be caused by any of the following: Brain and nervous system disorders, such as cerebral ... Follow your health care provider's instructions for treating contracture at home. Treatments may include: Doing exercises and ...

  3. Microhydrodynamics of deformable particles: surprising responses of drops and vesicles to uniform electric field or shear flow

    Science.gov (United States)

    Vlahovska, Petia

    2015-11-01

    Particle motion in a viscous fluid is a classic problem that continues to surprise researchers. In this talk, I will discuss some intriguing, experimentally-observed behaviors of droplets and giant vesicles (cell-size lipid membrane sacs) in electric or flow fields. In a uniform electric field, a droplet deforms into an ellipsoid that can either be steadily tilted relative to the applied field direction or undergo unsteady motions (periodic shape oscillations or irregular flipping); a spherical vesicle can adopt a transient square shape or reversibly porate. In a steady shear flow, a vesicle can tank-tread, tumble or swing. Theoretical models show that the nonlinear drop dynamics originates from the interplay of Quincke rotation and interface deformation, while the vesicle dynamics stems from the membrane inextensibility. The practical motivation for this research lies in an improved understanding of technologies that rely on the manipulation of drops and cells by flow or electric fields.

  4. Non-linear lattice response of Sm oxypnictides to hydrostatic pressure

    Science.gov (United States)

    Liarokapis, E.; Calamiotou, M.; Zhigadlo, N. D.; Katrych, S.; Karpinski, J.

    2013-10-01

    Hydrostatic pressure Raman measurements at room temperature have been carried out on the SmFeAsO (Sm1111) series of oxypnictides with various substitutions (F for O and Co for Fe) and transition temperature in order to investigate lattice modifications and their connection to doping and superconductivity. Synchrotron XRD data on some of these compounds indicated that at low doping the lattice constants vary smoothly with pressure, but with further increasing of the carrier concentration there is a deviation from the normal equation of state and these effects are related with modifications in the superconducting FeAs4 tetrahedra. The hydrostatic pressure Raman measurements indicate that the A1g mode of the rare earth atom for the superconducting compounds deviates from the linear pressure dependence at the same pressures where the XRD results show pressure-induced lattice anomalies. A similar anomaly is found for the As phonon of the same symmetry. As in cuprates, the effect is diminished in the non-superconducting compounds and it is not related with the F substitution being present in the Sm(Fe1-xCox)AsO as well. The calculated Grüneisen parameters indicate a more anharmonic phonon for the Fe atom compared with the Sm and As atoms.

  5. Electron-related linear and nonlinear optical responses in vertically coupled triangular quantum dots

    Energy Technology Data Exchange (ETDEWEB)

    Martínez-Orozco, J.C. [Unidad Académica de Física. Universidad Autónoma de Zacatecas, Calzada Solidaridad esquina con Paseo la Bufa S/N, C.P. 98060. Zacatecas, Zac. (Mexico); Grupo de Materia Condensada-UdeA, Instituto de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín (Colombia); Mora-Ramos, M.E. [Facultad de Ciencias, Universidad Autónoma del Estado de Morelos, Ave. Universidad 1001, CP 62209, Cuernavaca, Morelos (Mexico); Duque, C.A., E-mail: cduque@fisica.udea.edu.co [Grupo de Materia Condensada-UdeA, Instituto de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín (Colombia)

    2014-11-01

    The conduction band states of GaAs-based vertically coupled double triangular quantum dots in two dimensions are investigated within the effective mass and parabolic approximation, using a diagonalization procedure to solve the corresponding Schrödinger-like equation. The effect of an externally applied static electric field is included in the calculation, and the variation of the lowest confined energy levels as a result of the change of the field strength is reported for different geometrical setups. The linear and nonlinear optical absorptions and the relative change of the refractive index, associated with the energy transition between the ground and the first excited state in the system, are studied as a function of the incident light frequency for distinct configurations of inter-dot distance and electric field intensities. The blueshift of the resonant absorption peaks is detected as a consequence of the increment in the field intensity, whereas the opposite effect is obtained from the increase of inter-dot vertical distance. It is also shown that for large enough values of the electric field there is a quenching of the optical absorption due to field-induced change of symmetry of the first excited state wavefunction, in the case of triangular dots of equal shape and size.

  6. Physical origin of third order non-linear optical response of porphyrin nanorods

    Energy Technology Data Exchange (ETDEWEB)

    Mongwaketsi, N., E-mail: nanky@tlabs.ac.za [NANOAFNET, MRD- iThemba LABS, 1 Old Faure Road, Somerset West 7129 (South Africa); CSIR Biosciences, P.O. Box 395, Pretoria 0001 (South Africa); Khamlich, S. [NANOAFNET, MRD- iThemba LABS, 1 Old Faure Road, Somerset West 7129 (South Africa); Pranaitis, M. [LUNAM Universite, Universite d' Angers, CNRS UMR 6200, Laboratoire MOLTECH-Anjou, 2 bd Lavoisier, 49045 ANGERS cedex (France); Sahraoui, B., E-mail: bouchta.sahraoui@univ-angers.fr [LUNAM Universite, Universite d' Angers, CNRS UMR 6200, Laboratoire MOLTECH-Anjou, 2 bd Lavoisier, 49045 ANGERS cedex (France); Khammar, F. [Universite Cherif Messadia, BP: 1553, Souk-Ahras 41000 (Algeria); Garab, G. [Institute of Plant Biology, Biological Research Centre, P.O. Box 521, Szeged H-6701 (Hungary); Sparrow, R. [CSIR Biosciences, P.O. Box 395, Pretoria 0001 (South Africa); Maaza, M. [NANOAFNET, MRD- iThemba LABS, 1 Old Faure Road, Somerset West 7129 (South Africa)

    2012-06-15

    The non-linear optical properties of porphyrin nanorods were studied using Z-scan, Second and Third harmonic generation techniques. We investigated in details the heteroaggregate behaviour formation of [H{sub 4}TPPS{sub 4}]{sup 2-} and [SnTPyP]{sup 2+} mixture by means of the UV-VIS spectroscopy and aggregates structure and morphology by transmission electron microscopy. The porphyrin nanorods under investigation were synthesized by self assembly and molecular recognition method. They have been optimized in view of future application in the construction of the light harvesting system. The focus of this study was geared towards understanding the influence of the type of solvent used on these porphyrins nanorods using spectroscopic and microscopic techniques. Highlights: Black-Right-Pointing-Pointer We synthesized porphyrin nanorods by self assembly and molecular recognition method. Black-Right-Pointing-Pointer TEM images confirmed solid cylindrical shapes. Black-Right-Pointing-Pointer UV-VIS spectroscopy showed the decrease in the absorbance peaks of the precursors. Black-Right-Pointing-Pointer The enhanced third-order nonlinearities were observed.

  7. Growth and antioxidant response in Hydrocharis dubis (Bl.) Backer exposed to linear alkylbenzene sulfonate.

    Science.gov (United States)

    Wu, Zhonghua; Yu, Dan; Li, Jinlin; Wu, Gongguo; Niu, Xiaona

    2010-04-01

    A two-week exposure experiment was designed to investigate the toxicity of linear alkylbenzene sulfonate (LAS) on the aquatic plant Hydrocharis dubis (Bl.) Backer, focusing on growth, photosynthetic pigments and the activities of antioxidant enzymes. No significant differences were observed in the growth parameters of H. dubis when H. dubis was exposed to lower LAS doses (10 mg l(-1)) resulted in significant decreases in all growth parameters of H. dubis. No significant effect on pigment contents was observed at up to 50 mg l(-1) LAS, beyond which pigment contents declined gradually. Malondialdehyde (MDA) content did not show obvious differences when H. dubis plants were exposed to

  8. Gauge-invariant theories of linear response for strongly correlated superconductors

    Science.gov (United States)

    Boyack, Rufus; Anderson, Brandon M.; Wu, Chien-Te; Levin, K.

    2016-09-01

    We present a diagrammatic theory for determining consistent electromagnetic response functions in strongly correlated fermionic superfluids. While a gauge-invariant electromagnetic response is well understood at the BCS level, a treatment of correlations beyond BCS theory requires extending this theoretical formalism. The challenge in such systems is to maintain gauge invariance, while simultaneously incorporating additional self-energy terms arising from strong correlation effects. Central to our approach is the application of the Ward-Takahashi identity, which introduces collective mode contributions in the response functions and guarantees that the f -sum rule is satisfied. We outline a powerful method, which determines these collective modes in the presence of correlation effects and in a manner compatible with gauge invariance. Since this method is based on fundamental aspects of quantum field theory, the underlying principles are broadly applicable to strongly correlated superfluids. As an illustration of the technique, we apply it to a simple class of theoretical models that contain a frequency-independent order parameter. These models include BCS-BEC crossover theories of the ultracold Fermi gases, along with models specifically associated with the high-Tc cuprates. Finally, as an alternative approach, we contrast with the path integral formalism. Here, the calculation of gauge-invariant response appears more straightforward. However, the collective modes introduced are those of strict BCS theory, without any modification from additional correlations. As the path integral simultaneously addresses electrodynamics and thermodynamics, we emphasize that it should be subjected to a consistency test beyond gauge invariance, namely that of the compressibility sum rule. We show how this sum rule fails in the conventional path integral approach.

  9. Three-dimensional deformation response of a NiTi shape memory helical-coil actuator during thermomechanical cycling: experimentally validated numerical model

    Science.gov (United States)

    Dhakal, B.; Nicholson, D. E.; Saleeb, A. F.; Padula, S. A., II; Vaidyanathan, R.

    2016-09-01

    Shape memory alloy (SMA) actuators often operate under a complex state of stress for an extended number of thermomechanical cycles in many aerospace and engineering applications. Hence, it becomes important to account for multi-axial stress states and deformation characteristics (which evolve with thermomechanical cycling) when calibrating any SMA model for implementation in large-scale simulation of actuators. To this end, the present work is focused on the experimental validation of an SMA model calibrated for the transient and cyclic evolutionary behavior of shape memory Ni49.9Ti50.1, for the actuation of axially loaded helical-coil springs. The approach requires both experimental and computational aspects to appropriately assess the thermomechanical response of these multi-dimensional structures. As such, an instrumented and controlled experimental setup was assembled to obtain temperature, torque, degree of twist and extension, while controlling end constraints during heating and cooling of an SMA spring under a constant externally applied axial load. The computational component assesses the capabilities of a general, multi-axial, SMA material-modeling framework, calibrated for Ni49.9Ti50.1 with regard to its usefulness in the simulation of SMA helical-coil spring actuators. Axial extension, being the primary response, was examined on an axially-loaded spring with multiple active coils. Two different conditions of end boundary constraint were investigated in both the numerical simulations as well as the validation experiments: Case (1) where the loading end is restrained against twist (and the resulting torque measured as the secondary response) and Case (2) where the loading end is free to twist (and the degree of twist measured as the secondary response). The present study focuses on the transient and evolutionary response associated with the initial isothermal loading and the subsequent thermal cycles under applied constant axial load. The experimental

  10. EMS in Viracept--initial ('traditional') assessment of risk to patients based on linear dose response relations.

    Science.gov (United States)

    Gocke, Elmar; Müller, Lutz; Pfister, Thomas

    2009-11-12

    Prior to having performed in depth toxicological, genotoxicological and DMPK studies on ethyl methanesulfonate (EMS) providing solid evidence for a thresholded dose response relationship, we had prepared and shared with regulatory authorities a preliminary risk estimate based on standard linear dose-effect projections. We estimated that maximal lifetime cancer risk was in the order of 10(-3) (for lifetime ingestion of the maximally contaminated tablets) or 10(-4) for the exposure lasting for 3 months. This estimate was based on a lifetime cancer study with methyl methanesulfonate (MMS; as insufficient data were available for EMS) in rodents and default linear back extrapolation. Analogous estimates were made specifically for breast cancer based on short term tumorigenicity studies with EMS in rats, for the induction of heritable mutations based on specific locus and dominant lethal tests in mice and for the induction of birth defects based on teratogenicity studies in mice. We concluded that even under worst case assumptions of linear dose relations the chance of experiencing these adverse effects would be very small, comprising at most a minute additional burden among the background incidence of the patients.

  11. Impact of observed North Atlantic multidecadal variations to European summer climate: a linear baroclinic response to surface heating

    Science.gov (United States)

    Ghosh, Rohit; Müller, Wolfgang A.; Baehr, Johanna; Bader, Jürgen

    2017-06-01

    The observed prominent multidecadal variations in the central to eastern (C-E) European summer temperature are closely related to the Atlantic multidecadal variability (AMV). Using the Twentieth Century Reanalysis project version 2 data for the period of 1930-2012, we present a mechanism by which the multidecadal variations in the C-E European summer temperature are associated to a linear baroclinic atmospheric response to the AMV-related surface heat flux. Our results suggest that over the north-western Atlantic, the positive heat flux anomaly triggers a surface baroclinic pressure response to diabatic heating with a negative surface pressure anomaly to the east of the heat source. Further downstream, this response induces an east-west wave-like pressure anomaly. The east-west wave-like response in the sea level pressure structure, to which we refer as North-Atlantic-European East West (NEW) mode, is independent of the summer North Atlantic Oscillation and is the principal mode of variations during summer over the Euro-Atlantic region at multidecadal time scales. The NEW mode causes warming of the C-E European region by creating an atmospheric blocking-like situation. Our findings also suggest that this NEW mode is responsible for the multidecadal variations in precipitation over the British Isles and north-western Europe.

  12. Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach.

    Science.gov (United States)

    Schacht, Joseph P; Anton, Raymond F; Randall, Patrick K; Li, Xingbao; Henderson, Scott; Myrick, Hugh

    2011-05-01

    In functional magnetic resonance imaging (fMRI) studies of alcohol-dependent individuals, alcohol cues elicit activation of the ventral and dorsal aspects of the striatum (VS and DS), which are believed to underlie aspects of reward learning critical to the initiation and maintenance of alcohol dependence. Cue-elicited striatal activation may represent a biological substrate through which treatment efficacy may be measured. However, to be useful for this purpose, VS or DS activation must first demonstrate stability across time. Using hierarchical linear modeling (HLM), this study tested the stability of cue-elicited activation in anatomically and functionally defined regions of interest in bilateral VS and DS. Nine non-treatment-seeking alcohol-dependent participants twice completed an alcohol cue reactivity task during two fMRI scans separated by 14 days. HLM analyses demonstrated that, across all participants, alcohol cues elicited significant activation in each of the regions of interest. At the group level, these activations attenuated slightly between scans, but session-wise differences were not significant. Within-participants stability was best in the anatomically defined right VS and DS and in a functionally defined region that encompassed right caudate and putamen (intraclass correlation coefficients of .75, .81, and .76, respectively). Thus, within this small sample, alcohol cue-elicited fMRI activation had good reliability in the right striatum, though a larger sample is necessary to ensure generalizability and further evaluate stability. This study also demonstrates the utility of HLM analytic techniques for serial fMRI studies, in which separating within-participants variance (individual changes in activation) from between-participants factors (time or treatment) is critical. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Natural vibration response based damage detection for an operating wind turbine via Random Coefficient Linear Parameter Varying AR modelling

    Science.gov (United States)

    Avendaño-Valencia, L. D.; Fassois, S. D.

    2015-07-01

    The problem of damage detection in an operating wind turbine under normal operating conditions is addressed. This is characterized by difficulties associated with the lack of measurable excitation(s), the vibration response non-stationary nature, and its dependence on various types of uncertainties. To overcome these difficulties a stochastic approach based on Random Coefficient (RC) Linear Parameter Varying (LPV) AutoRegressive (AR) models is postulated. These models may effectively represent the non-stationary random vibration response under healthy conditions and subsequently used for damage detection through hypothesis testing. The performance of the method for damage and fault detection in an operating wind turbine is subsequently assessed via Monte Carlo simulations using the FAST simulation package.

  14. Response analysis of a class of quasi-linear systems with fractional derivative excited by Poisson white noise.

    Science.gov (United States)

    Yang, Yongge; Xu, Wei; Yang, Guidong; Jia, Wantao

    2016-08-01

    The Poisson white noise, as a typical non-Gaussian excitation, has attracted much attention recently. However, little work was referred to the study of stochastic systems with fractional derivative under Poisson white noise excitation. This paper investigates the stationary response of a class of quasi-linear systems with fractional derivative excited by Poisson white noise. The equivalent stochastic system of the original stochastic system is obtained. Then, approximate stationary solutions are obtained with the help of the perturbation method. Finally, two typical examples are discussed in detail to demonstrate the effectiveness of the proposed method. The analysis also shows that the fractional order and the fractional coefficient significantly affect the responses of the stochastic systems with fractional derivative.

  15. Computation of Raman Spectra from Density Matrix Linear Response Theory in Extended Lagrangian Born-Oppenheimer Molecular Dynamics

    Science.gov (United States)

    Niklasson, Anders; Coe, Joshua; Cawkwell, Marc

    2011-06-01

    Linear response calculations based on density matrix perturbation theory [A. M. N. Niklasson and M. Challacombe, Phys. Rev. Lett. 92, 193001 (2004)] have been developed within a self-consistent tight-binding method for extended Lagrangian Born-Oppenheimer molecular dynamics [A. M. N. Niklasson, Phys. Rev. Lett., 100, 123004 (2008)]. Besides the nuclear coordinates, extended auxiliary electronic degrees of freedom are added to the regular Born-Oppenheimer Lagrangian, both for the electronic ground state and response densities. This formalism enables highly efficient, on-the-fly, analytic computations of the polarizability autocorrelation functions and the Raman spectra during energy conserving Born-Oppenheimer molecular dynamics trajectories. We will illustrate these capabilities via time-resolved Raman spectra computed during explicit, reactive molecular dynamics simulations of the shock compression of methane, benzene, tert-butylacetylene. Comparisons will be made with experimental results where possible.

  16. Long-memory effects in linear-response models of Earth's temperature and implications for future global warming

    CERN Document Server

    Rypdal, Martin

    2013-01-01

    A linearized energy-balance model for global temperature is formulated, featuring a scale-free long-range memory (LRM) response and stochastic forcing representing the influence on the ocean heat reservoir from atmospheric weather systems. The model is parametrized by an effective response strength, the stochastic forcing strength, and the memory exponent. The instrumental global surface temperature record and the deterministic component of the forcing are used to estimate these parameters by means of the maximum-likelihood method. The residual obtained by subtracting the deterministic solution from the observed record is analyzed as a noise process and shown to be consistent with a long-memory time-series model and inconsistent with a short-memory model. By decomposing the forcing record in contributions from solar, volcanic, and anthropogenic activity one can estimate the contribution of each to 20'th century global warming. The LRM model is applied with a reconstruction of the forcing for the last millenni...

  17. Elastocapillary Deformations and Fracture of Soft Gels

    Science.gov (United States)

    Daniels, Karen; Grzelka, Marion; Bostwick, Joshua

    When a droplet is placed on the surface of a soft gel, the surface deforms by an amount proportional to the elastocapillary length calculated from the ratio of surface tension and elastic modulus. For sufficiently large deformations, the gel can fracture due to the forces generated under the liquid-gel contact line. We observe that a starburst of channel fractures forms at the surface of the gel, driven by fluid propagating away from the central droplet. To understand the initiation of these cracks, we model the substrate as an incompressible, linear-elastic solid and quantify the elastic response. This provides quantitative agreement with experimental measurements of the number of fracture arms as a function of material properties and geometric parameters. In addition, we find that the initiation process is thermally-activated, with delay time that decreases as a function of the elastocapillary length.

  18. Signal transmission from motor axons to group Ia muscle spindle afferents: frequency responses and second-order non-linearities.

    Science.gov (United States)

    Windhorst, U; Kokkoroyiannis, T; Laouris, Y; Meyer-Lohmann, J

    1994-03-01

    Spinal recurrent inhibition via Renshaw cells and proprioceptive feedback via skeletal muscle and muscle spindle afferents have been hypothesized to constitute a compound feedback system [Windhorst (1989) Afferent Control of Posture and Locomotion; Windhorst (1993) Robots and Biological Systems--Towards a New Bionics]. To assess their detailed functions, it is necessary to know their dynamic characteristics. Previously we have extensively described the properties of signal transmission from motor axons to Renshaw cells using random motor axon stimulation and data analysis methods based thereupon. Using the same methods, we here compare these properties, in the cat, with those between motor axons and group Ia muscle spindle afferents in terms of frequency responses and nonlinear features. The frequency responses depend on the mean rate (carrier rate) of activation of motor axons and on the strength of coupling between motor units and spindles. In general, they are those of a second-order low-pass system with a cut-off at fairly low frequencies. This contrasts with the dynamics of motor axon-Renshaw cell couplings which are those of a much broader band-pass with its peak in the range of c. 2-15 Hz [Christakos (1987) Neuroscience 23, 613-623]. The second-order non-linearities in motor unit-muscle spindle signal lines are much more diverse than those in motor axon-Renshaw cell couplings. Although the average strength of response declines with mean stimulus rate in both subsystems, there is no systematic relationship between the amount of non-linearity and the average response in the former, whilst there is in the latter. The qualitative appearance of motor unit-muscle spindle non-linearities was complicated as was the average response to motor unit twitches. Thus, whilst Renshaw cells appear to dynamically reflect motor output rather faithfully, muscle spindles seem to signal local muscle fibre length changes and their dynamics. This would be consistent with the

  19. Linear-response theory of Coulomb drag in coupled electron systems

    DEFF Research Database (Denmark)

    Flensberg, Karsten; Hu, Ben Yu-Kuang; Jauho, Antti-Pekka

    1995-01-01

    are topologically related but not equivalent to the Aslamazov-Larkin diagrams known from superconductivity. Results reported elsewhere are shown to be special cases of our general expression; specifically, we recover the Boltzmann equation result in the semiclassical clean limit and the memory function results...... for dirty systems with constant impurity scattering rates. Furthermore, we show that for energy-dependent relaxation times, the final result is not expressible in terms of standard density-response functions. Other results include (i) at T = 0, the frequency dependence of the transfer rate is found...

  20. Linear and fractional response for the SRB measure of smooth hyperbolic attractors and discontinuous observables

    Science.gov (United States)

    Baladi, Viviane; Kuna, Tobias; Lucarini, Valerio

    2017-03-01

    We consider a smooth one-parameter family t\\mapsto ≤ft( {{f}t}:M\\to M\\right) of diffeomorphisms with compact transitive Axiom A attractors {{ Λ }t} , denoting by \\text{d}{ρt} the SRB measure of {{f}t}{{|}{{ Λ t}}} . Our first result is that for any function θ in the Sobolev space Hpr(M) , with 1 and 0  fractional response for such observables θ is motivated by extreme-value theory.

  1. Leukocyte deformability: finite element modeling of large viscoelastic deformation.

    Science.gov (United States)

    Dong, C; Skalak, R

    1992-09-21

    An axisymmetric deformation of a viscoelastic sphere bounded by a prestressed elastic thin shell in response to external pressure is studied by a finite element method. The research is motivated by the need for understanding the passive behavior of human leukocytes (white blood cells) and interpreting extensive experimental data in terms of the mechanical properties. The cell at rest is modeled as a sphere consisting of a cortical prestressed shell with incompressible Maxwell fluid interior. A large-strain deformation theory is developed based on the proposed model. General non-linear, large strain constitutive relations for the cortical shell are derived by neglecting the bending stiffness. A representation of the constitutive equations in the form of an integral of strain history for the incompressible Maxwell interior is used in the formulation of numerical scheme. A finite element program is developed, in which a sliding boundary condition is imposed on all contact surfaces. The mathematical model developed is applied to evaluate experimental data of pipette tests and observations of blood flow.

  2. The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population.

    Science.gov (United States)

    Holman, Rebecca; Weisscher, Nadine; Glas, Cees A W; Dijkgraaf, Marcel G W; Vermeulen, Marinus; de Haan, Rob J; Lindeboom, Robert

    2005-12-29

    Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55%) residents of supported housing, residential care or nursing homes; 235 (23%) patients with chronic pain; 127 (13%) inpatients on a neurology ward following a stroke; and 89 (9%) patients suffering from Parkinson's disease. Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations.

  3. The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population

    Science.gov (United States)

    Holman, Rebecca; Weisscher, Nadine; Glas, Cees AW; Dijkgraaf, Marcel GW; Vermeulen, Marinus; de Haan, Rob J; Lindeboom, Robert

    2005-01-01

    Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. Methods This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55%) residents of supported housing, residential care or nursing homes; 235 (23%) patients with chronic pain; 127 (13%) inpatients on a neurology ward following a stroke; and 89 (9%) patients suffering from Parkinson's disease. Results Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. Conclusion The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations. PMID:16381611

  4. The Academic Medical Center Linear Disability Score (ALDS item bank: item response theory analysis in a mixed patient population

    Directory of Open Access Journals (Sweden)

    Vermeulen Marinus

    2005-12-01

    Full Text Available Abstract Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. Methods This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55% residents of supported housing, residential care or nursing homes; 235 (23% patients with chronic pain; 127 (13% inpatients on a neurology ward following a stroke; and 89 (9% patients suffering from Parkinson's disease. Results Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. Conclusion The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations.

  5. Do Quercus ilex woodlands undergo abrupt non-linear functional changes in response to human disturbance along a climatic gradient?

    Science.gov (United States)

    Bochet, Esther; García-Fayos, Patricio; José Molina, Maria; Moreno de las Heras, Mariano; Espigares, Tíscar; Nicolau, Jose Manuel; Monleon, Vicente

    2017-04-01

    Theoretical models predict that drylands are particularly prone to suffer critical transitions with abrupt non-linear changes in their structure and functions as a result of the existing complex interactions between climatic fluctuations and human disturbances. However, so far, few studies provide empirical data to validate these models. We aim at determining how holm oak (Quercus ilex) woodlands undergo changes in their functions in response to human disturbance along an aridity gradient (from semi-arid to sub-humid conditions), in eastern Spain. For that purpose, we used (a) remote-sensing estimations of precipitation-use-efficiency (PUE) from enhanced vegetation index (EVI) observations performed in 231x231 m plots of the Moderate Resolution Imaging Spectroradiometer (MODIS); (b) biological and chemical soil parameter determinations (extracellular soil enzyme activity, soil respiration, nutrient cycling processes) from soil sampled in the same plots; (c) vegetation parameter determinations (ratio of functional groups) from vegetation surveys performed in the same plots. We analyzed and compared the shape of the functional change (in terms of PUE and soil and vegetation parameters) in response to human disturbance intensity for our holm oak sites along the aridity gradient. Overall, our results evidenced important differences in the shape of the functional change in response to human disturbance between climatic conditions. Semi-arid areas experienced a more accelerated non-linear decrease with an increasing disturbance intensity than sub-humid ones. The proportion of functional groups (herbaceous vs. woody cover) played a relevant role in the shape of the functional response of the holm oak sites to human disturbance.

  6. Glycemic Response and Fermentation of Crystalline Short Linear α-Glucans from Debranched Waxy Maize Starch.

    Science.gov (United States)

    Brewer, Lauren R; Weber, Casey; Haub, Mark; Cai, Liming; Shi, Yong-Cheng

    2015-11-04

    The glycemic index (GI) is used to rank foods based on postprandial blood glucose response. GI test requires that 50 g of available carbohydrate be used. Available carbohydrate is often calculated as total carbohydrate minus dietary fiber; yet, AOAC fiber methods do not always include resistant starch (RS). The objective of this study was to examine GI response and fermentation properties of crystalline short-chain α-glucan (CSCA), which has high RS content, but no total dietary fiber (TDF) content as measured by AOAC method 991.43. Using the standard GI method, 10 adults were fed 50 g of waxy maize starch and CSCA, consumed alone and in mixed formulation. Breath hydrogen was also determined over 6 h. Fifty grams of CSCA was not entirely available in vivo, and breath hydrogen testing indicated that CSCA was as likely to ferment. Products high in RS, but with no TDF, would yield reduced GI values, and this calls for the need of a method to define available carbohydrate.

  7. Stable response of low-gravity liquid non-linear sloshing in a circle cylindrical tank

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Under pitch excitation, the sloshing of liquid in circular cylindrical tank includes planar motion, rotary motion and rotary motion inside planar motion. The boundaries between stable motion and unstable motion depend on the radius of the tank, the liquid height, the gravitational intension, the surface tensor and the sloshing damping. In this article, the differential equations of nonlinear sloshing are built first.And by variational principle, the Lagrange function of liquid pressure is constructed in volume intergration form. Then the velocity potential function is expanded in series by wave height function at the free surface. The nonlinear equations with kinematics and dynamics free surface boundary conditions through variation are derived. At last, these equations are solved by multiple-scales method. The influence of Bond number on the global stable response of nonlinear liquid sloshing in circular cylinder tank is analyzed in detail. The result indicates that variation of amplitude frequency response characteristics of the system with Bond, jump, lag and other nonlinear phenomena of liquid sloshing are investigated.

  8. Swelling and Shrinking Properties of Thermo-Responsive Polymeric Ionic Liquid Hydrogels with Embedded Linear pNIPAAM

    Directory of Open Access Journals (Sweden)

    Simon Gallagher

    2014-03-01

    Full Text Available In this study, varying concentrations of linear pNIPAAM have been incorporated for the first time into a thermo-responsive polymeric ionic liquid (PIL hydrogel, namely tributyl-hexyl phosphonium 3-sulfopropylacrylate (P-SPA, to produce semi-interpenetrating polymer networks. The thermal properties of the resulting hydrogels have been investigated along with their thermo-induced shrinking and reswelling capabilities. The semi-interpenetrating networks (IPN hydrogels were found to have improved shrinking and reswelling properties compared with their PIL counterpart. At elevated temperatures (50–80 °C, it was found that the semi-IPN with the highest concentration of hydrophobic pNIPAAM exhibited the highest shrinking percentage of ~40% compared to the conventional P-SPA, (27%. This trend was also found to occur for the reswelling measurements, with semi-IPN hydrogels producing the highest reswelling percentage of ~67%, with respect to its contracted state. This was attributed to an increase in water affinity due to the presence of hydrophilic pNIPAAM. Moreover, the presence of linear pNIPAAM in the polymer matrix leads to improved shrinking and reswelling response compared to the equivalent PIL.

  9. Speed optimized linear-mode high-voltage CMOS avalanche photodiodes with high responsivity.

    Science.gov (United States)

    Enne, R; Steindl, B; Zimmermann, H

    2015-10-01

    Two different speed optimized avalanche photodiodes (APDs) fabricated in a 0.35 μm standard high-voltage (HV) complementary metal-oxide-semiconductor (CMOS) process with a high unamplified responsivity (avalanche gain M=1) of 0.41 A/W at 670 nm are presented. These APDs differ regarding the effective doping of the deep p well (90% and 75%), using lateral well modulation doping. Compared to the -3  dB bandwidth of the unmodulated APD with 100% doping (850 MHz), this optimization leads to an improved bandwidth of 1.02 and 1.25 GHz for the 75% APD and 90% APD, respectively, both at a gain of M=50.

  10. Non-linear buffeting response analysis of long-span suspension bridges with central buckle

    Science.gov (United States)

    Wang, Hao; Li, Aiqun; Zhao, Gengwen; Li, Jian

    2010-06-01

    The rigid central buckle employed in the Runyang Suspension Bridge (RSB) was the first time it was used in a suspension bridge in China. By using a spectral representation method and FFT technique combined with measured data, a 3D fluctuating wind field considering the tower wind effect is simulated. A novel FE model for buffeting analysis is then presented, in which a specific user-defined Matrix27 element in ANSYS is employed to simulate the aeroelastic forces and its stiffness or damping matrices are parameterized by wind velocity and vibration frequency. A nonlinear time history analysis is carried out to study the influence of the rigid central buckle on the wind-induced buffeting response of a long-span suspension bridge. The results can be used as a reference for wind resistance design of long-span suspension bridges with a rigid central buckle in the future.

  11. Direct Forecasting of Subsurface Flow Response from Non-Linear Dynamic Data By Linear Least-Squares in Canonical Functional Principal Component Space.

    Science.gov (United States)

    Satija, A.; Caers, J.

    2014-12-01

    Hydrogeological forecasting problems, like many subsurface forecasting problems, often suffer from the scarcity of reliable data yet complex prior information about the underlying earth system. Assimilating and integrating this information into an earth model requires using iterative parameter space exploration techniques or Monte Carlo Markov Chain techniques. Since such an earth model needs to account for many large and small scale features of the underlying system, as the system gets larger, iterative modeling can become computationally prohibitive, in particular when the forward model would allow for only a few hundred model evaluations. In addition, most modeling methods do not include the purpose for which inverse method are built, namely, the actual forecast and usually focus only on data and model. In this study, we present a technique to extract features of the earth system informed by time-varying dynamic data (data features) and those that inform a time-varying forecasting variable (forecast features) using Functional Principal Component Analysis. Canonical Coefficient Analysis is then used to examine the relationship between these features using a linear model. When this relationship suggests that the available data informs the required forecast, a simple linear regression can be used on the linear model to directly estimate the posterior of the forecasting problem, without any iterative inversion of model parameters. This idea and method is illustrated using an example of contaminant flow in an aquifer with complex prior, large dimension and non-linear flow & transport model.

  12. Non-linear responses of glaciated prairie wetlands to climate warming

    Science.gov (United States)

    Johnson, W. Carter; Werner, Brett; Guntenspergen, Glenn R.

    2016-01-01

    The response of ecosystems to climate warming is likely to include threshold events when small changes in key environmental drivers produce large changes in an ecosystem. Wetlands of the Prairie Pothole Region (PPR) are especially sensitive to climate variability, yet the possibility that functional changes may occur more rapidly with warming than expected has not been examined or modeled. The productivity and biodiversity of these wetlands are strongly controlled by the speed and completeness of a vegetation cover cycle driven by the wet and dry extremes of climate. Two thresholds involving duration and depth of standing water must be exceeded every few decades or so to complete the cycle and to produce highly functional wetlands. Model experiments at 19 weather stations employing incremental warming scenarios determined that wetland function across most of the PPR would be diminished beyond a climate warming of about 1.5–2.0 °C, a critical temperature threshold range identified in other climate change studies.

  13. Modeling the Non-linear Viscoelastic Response of High Temperature Polyimides

    CERN Document Server

    Karra, Satish

    2010-01-01

    A constitutive model is developed to predict the viscoelastic response of polyimide resins that are used in high temperature applications. This model is based on a thermodynamic framework that uses the notion that the `natural configuration' of a body evolves as the body undergoes a process and the evolution is determined by maximizing the rate of entropy production in general and the rate of dissipation within purely mechanical considerations. We constitutively prescribe forms for the specific Helmholtz potential and the rate of dissipation (which is the product of density, temperature and the rate of entropy production), and the model is derived by maximizing the rate of dissipation with the constraint of incompressibility, and the reduced energy dissipation equation is also regarded as a constraint in that it is required to be met in every process that the body undergoes. The efficacy of the model is ascertained by comparing the predictions of the model with the experimental data for PMR-15 and HFPE-II-52 ...

  14. Origins of Total-Dose Response Variability in Linear Bipolar Microcircuits

    Energy Technology Data Exchange (ETDEWEB)

    BARNABY,H.J.; CIRBA,C.R.; SCHRIMPF,R.D.; FLEETWOOD,D.M.; PEASE,R.L.; SHANEYFELT,MARTY R.; TURFLINGER,T.; KRIEG,J.F.; MAHER,M.C.

    2000-11-15

    LM1ll voltage comparators exhibit a wide range of total-dose-induced degradation. Simulations show this variability may be a natural consequence of the low base doping of the substrate PNP (SPNP) input transistors. Low base doping increases the SPNP's collector to base breakdown voltage, current gain, and sensitivity to small fluctuations in the radiation-induced oxide defect densities. The build-up of oxide trapped charge (N{sub ot}) and interface traps (N{sub it}) is shown to be a function of pre-irradiation bakes. Experimental data indicate that, despite its structural similarities to the LM111, irradiated input transistors of the LM124 operational amplifier do not exhibit the same sensitivity to variations in pre-irradiation thermal cycles. Further disparities in LM111 and LM124 responses may result from a difference in the oxide defect build-up in the two part types. Variations in processing, packaging, and circuit effects are suggested as potential explanations.

  15. Gradient Domain Mesh Deformation - A Survey

    Institute of Scientific and Technical Information of China (English)

    Wei-Wei Xu; Kun Zhou

    2009-01-01

    This survey reviews the recent development of gradient domain mesh deformation method. Different to other deformation methods, the gradient domain deformation method is a surface-based, variational optimization method. It directly encodes the geometric details in differential coordinates, which are also called Laplacian coordinates in literature. By preserving the Laplacian coordinates, the mesh details can be well preserved during deformation. Due to the locality of the Laplacian coordinates, the variational optimization problem can be casted into a sparse linear system. Fast sparse linear solver can be adopted to generate deformation result interactively, or even in real-time. The nonlinear nature of gradient domain mesh deformation leads to the development of two categories of deformation methods: linearization methods and nonlinear optimization methods. Basically, the linearization methods only need to solve the linear least-squares system once. They are fast, easy to understand and control, while the deformation result might be suboptimal. Nonlinear optimization methods can reach optimal solution of deformation energy function by iterative updating. Since the computation of nonlinear methods is expensive, reduced deformable models should be adopted to achieve interactive performance. The nonlinear optimization methods avoid the user burden to input transformation at deformation handles, and they can be extended to incorporate various nonlinear constraints, like volume constraint, skeleton constraint, and so on. We review representative methods and related approaches of each category comparatively and hope to help the user understand the motivation behind the algorithms. Finally, we discuss the relation between physical simulation and gradient domain mesh deformation to reveal why it can achieve physically plausible deformation result.

  16. Response of the electron work function to deformation and yielding behavior of copper under different stress states

    Energy Technology Data Exchange (ETDEWEB)

    Li Wen [Dept. of Mechanical Engineering, Changchun University (China); Dept. of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta (Canada); Wang, Y.; Li, D.Y. [Dept. of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta (Canada)

    2004-07-01

    The high sensitivity of the electron work function (EWF) to surface condition has attracted increasing interests from materials scientists and engineers. In this study, using a scanning Kelvin probe changes in the EWF of copper under various loading condition and stress states were investigated. Experimental results showed that the tensile strain decreased the EWF in the elastic deformation range, while compressive strain increased the EWF. However, the EWF in the plastic deformation range always decreased with plastic strain no matter it was tensile or compressive. As shown by the simultaneous measurements of the EWF under conditions of plane stress states, yielding point can be related to the critical stress for the transition of the EWF from smooth variation to steep variation, which strongly depended on stress states. It was therefore demonstrated that Kelvin probing technique could be used for determining the onset of yielding since the EWF was a parameter sensitive to yielding process. The Kelvin probing has appeared to be a very promising method for characterizing the yielding behaviors under complex stress states for both homogeneous and inhomogeneous materials. (copyright 2004 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  17. Deformation microstructures

    DEFF Research Database (Denmark)

    Hansen, N.; Huang, X.; Hughes, D.A.

    2004-01-01

    Microstructural characterization and modeling has shown that a variety of metals deformed by different thermomechanical processes follows a general path of grain subdivision, by dislocation boundaries and high angle boundaries. This subdivision has been observed to very small structural scales...... of the order of 10 nm, produced by deformation under large sliding loads. Limits to the evolution of microstructural parameters during monotonic loading have been investigated based on a characterization by transmission electron microscopy. Such limits have been observed at an equivalent strain of about 10...

  18. Large deformations of a soft porous material

    CERN Document Server

    MacMinn, Christopher W; Wettlaufer, John S

    2015-01-01

    Compressing a porous material will decrease the volume of pore space, driving fluid out. Similarly, injecting fluid into a porous material can drive mechanical deformation, distorting the solid skeleton. This poromechanical coupling has applications ranging from cell and tissue mechanics to geomechanics and hydrogeology. The classical theory of linear poroelasticity captures this coupling by combining Darcy's law with linear elasticity and then further linearizing in the strain. This is a good model for very small deformations, but it becomes increasingly inappropriate as deformations grow larger, and moderate to large deformations are common in the context of phenomena such as swelling or damage, or for materials that are extremely soft. Here, we first review a rigorous Eulerian framework for large-deformation poromechanics. We then compare the predictions of linear poroelasticity with those of fully nonlinear poromechanics in the context of two uniaxial model problems: Fluid outflow driven by an applied mec...

  19. Time-dependent quantum many-body systems. Linear response, electronic transport, and reduced density matrices

    Energy Technology Data Exchange (ETDEWEB)

    Appel, H.

    2007-05-15

    In part I of this work we present a double-pole approximation (DPA) to the response equations of time-dependent density functional theory (TDDFT). The double-pole approximation provides an exact description of systems with two strongly coupled excitations which are isolated from the rest of the spectrum. In contrast to the traditional single-pole approximation of TDDFT the DPA also yields corrections to the Kohn-Sham oscillator strengths. We also demonstrate how to invert the double-pole solution which allows us to predict matrix elements of the exchange-correlation kernel f{sub xc} from experimental input. We attempt some first steps towards a time-dependent generalization of reduced density matrix functional theory (RDMFT). In part II we derive equations of motion for natural orbitals and occupation numbers. Using the equation of motion for the occupation numbers we show that an adiabatic extension of presently known ground-state functionals of static RDMFT always leads to occupation numbers which are constant in time. From the stationary conditions of the equations of motion for the N-body correlations (correlated parts of the N-body matrices) we derive a new class of ground-state functionals which can be used in static RDMFT. Applications are presented for a one-dimensional model system where the time-dependent many-body Schroedinger equation can be propagated numerically. We use optimal control theory to find optimized laser pulses for transitions in a model for atomic Helium. From the numerically exact correlated wavefunction we extract the exact time evolution of natural orbitals and occupation numbers for (i) laser-driven Helium and (ii) electron-ion scattering. Part III of this work considers time-dependent quantum transport within TDDFT. We present an algorithm for the calculation of extended eigenstates of single-particle Hamiltonians which is especially tailored to a finite-difference discretization of the Schroedinger equation. We consider the

  20. Inelastic deformation in crystalline rocks

    Science.gov (United States)

    Rahmani, H.; Borja, R. I.

    2011-12-01

    The elasto-plastic behavior of crystalline rocks, such as evaporites, igneous rocks, or metamorphic rocks, is highly dependent on the behavior of their individual crystals. Previous studies indicate that crystal plasticity can be one of the dominant micro mechanisms in the plastic deformation of crystal aggregates. Deformation bands and pore collapse are examples of plastic deformation in crystalline rocks. In these cases twinning within the grains illustrate plastic deformation of crystal lattice. Crystal plasticity is governed by the plastic deformation along potential slip systems of crystals. Linear dependency of the crystal slip systems causes singularity in the system of equations solving for the plastic slip of each slip system. As a result, taking the micro-structure properties into account, while studying the overall behavior of crystalline materials, is quite challenging. To model the plastic deformation of single crystals we use the so called `ultimate algorithm' by Borja and Wren (1993) implemented in a 3D finite element framework to solve boundary value problems. The major advantage of this model is that it avoids the singularity problem by solving for the plastic slip explicitly in sub steps over which the stress strain relationship is linear. Comparing the results of the examples to available models such as Von Mises we show the significance of considering the micro-structure of crystals in modeling the overall elasto-plastic deformation of crystal aggregates.

  1. A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen

    Directory of Open Access Journals (Sweden)

    Lebedeva Galina

    2012-11-01

    Full Text Available Abstract Background Estrogen receptors alpha (ER are implicated in many types of female cancers, and are the common target for anti-cancer therapy using selective estrogen receptor modulators (SERMs, such as tamoxifen. However, cell-type specific and patient-to-patient variability in response to SERMs (from suppression to stimulation of cancer growth, as well as frequent emergence of drug resistance, represents a serious problem. The molecular processes behind mixed effects of SERMs remain poorly understood, and this strongly motivates application of systems approaches. In this work, we aimed to establish a mathematical model of ER-dependent gene expression to explore potential mechanisms underlying the variable actions of SERMs. Results We developed an equilibrium model of ER binding with 17β-estradiol, tamoxifen and DNA, and linked it to a simple ODE model of ER-induced gene expression. The model was parameterised on the broad range of literature available experimental data, and provided a plausible mechanistic explanation for the dual agonism/antagonism action of tamoxifen in the reference cell line used for model calibration. To extend our conclusions to other cell types we ran global sensitivity analysis and explored model behaviour in the wide range of biologically plausible parameter values, including those found in cancer cells. Our findings suggest that transcriptional response to tamoxifen is controlled in a complex non-linear way by several key parameters, including ER expression level, hormone concentration, amount of ER-responsive genes and the capacity of ER-tamoxifen complexes to stimulate transcription (e.g. by recruiting co-regulators of transcription. The model revealed non-monotonic dependence of ER-induced transcriptional response on the expression level of ER, that was confirmed experimentally in four variants of the MCF-7 breast cancer cell line. Conclusions We established a minimal mechanistic model of ER-dependent gene

  2. Non-linear finite element analysis for prediction of seismic response of buildings considering soil-structure interaction

    Directory of Open Access Journals (Sweden)

    E. Çelebi

    2012-11-01

    Full Text Available The objective of this paper focuses primarily on the numerical approach based on two-dimensional (2-D finite element method for analysis of the seismic response of infinite soil-structure interaction (SSI system. This study is performed by a series of different scenarios that involved comprehensive parametric analyses including the effects of realistic material properties of the underlying soil on the structural response quantities. Viscous artificial boundaries, simulating the process of wave transmission along the truncated interface of the semi-infinite space, are adopted in the non-linear finite element formulation in the time domain along with Newmark's integration. The slenderness ratio of the superstructure and the local soil conditions as well as the characteristics of input excitations are important parameters for the numerical simulation in this research. The mechanical behavior of the underlying soil medium considered in this prediction model is simulated by an undrained elasto-plastic Mohr-Coulomb model under plane-strain conditions. To emphasize the important findings of this type of problems to civil engineers, systematic calculations with different controlling parameters are accomplished to evaluate directly the structural response of the vibrating soil-structure system. When the underlying soil becomes stiffer, the frequency content of the seismic motion has a major role in altering the seismic response. The sudden increase of the dynamic response is more pronounced for resonance case, when the frequency content of the seismic ground motion is close to that of the SSI system. The SSI effects under different seismic inputs are different for all considered soil conditions and structural types.

  3. Confirmation of linear system theory prediction: Rate of change of Herrnstein's κ as a function of response-force requirement

    Science.gov (United States)

    McDowell, J. J; Wood, Helena M.

    1985-01-01

    Four human subjects worked on all combinations of five variable-interval schedules and five reinforcer magnitudes (¢/reinforcer) in each of two phases of the experiment. In one phase the force requirement on the operandum was low (1 or 11 N) and in the other it was high (25 or 146 N). Estimates of Herrnstein's κ were obtained at each reinforcer magnitude. The results were: (1) response rate was more sensitive to changes in reinforcement rate at the high than at the low force requirement, (2) κ increased from the beginning to the end of the magnitude range for all subjects at both force requirements, (3) the reciprocal of κ was a linear function of the reciprocal of reinforcer magnitude for seven of the eight data sets, and (4) the rate of change of κ was greater at the high than at the low force requirement by an order of magnitude or more. The second and third findings confirm predictions made by linear system theory, and replicate the results of an earlier experiment (McDowell & Wood, 1984). The fourth finding confirms a further prediction of the theory and supports the theory's interpretation of conflicting data on the constancy of Herrnstein's κ. PMID:16812408

  4. Empirical likelihood-based dimension reduction inference for linear error-in-responses models with validation study

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    [1]Fuller, W. A., Measurement Error Models, New York: John Wiley & Sons Inc., 1987.[2]Carroll, R. J., Ruppert, D., Stefanski, L. W., Measurement Error in Nonlinear Models, New York: Chapman and Hall, 1995.[3]Wittes, J., Lakatos, E., Probstfied, J., Surrogate endpoints in clinical trails: Cardiovascular diseases, Statist,Med., 1989, 8: 415-425.[4]Buonaccorsi, J. P., Measurement error in the response in the general linear model, J. Amer. Statist. Assoc., 1996,91(434): 633-642.[5]Carroll, R. J., Stefanski, L. A., Approximate quasi-likelihood estimation in models with surrogate predictors, J.Amer. Statist. Assoc., 1990, 85: 652-663.[6]Pepe, M. S., Inference using surrogate outcome data and a validation sample, Biometrika, 1992, 79: 355-365.[7]Duncan, G., Hill, D., An investigations of the extent and consequences of measurement error in labor-economics survey data, Journal of Labor Economics, 1985, 3: 508-532.[8]Stefanski, L. A., Carrol, R. J., Conditional scores and optimal scores for generalized linear measurement error models, Biometrika, 1987, 74:703-716.[9]Carroll, R. J., Wand, M. P., Semiparametric estimation in logistic measure error models, J. Roy. Statist. Soc.,Ser B, 1991, 53: 652-663.[10]Pepe, M. S., Fleming, T. R., A general nonparametric method for dealing with errors in missing or surrogate covariate data, J. Amer. Statist. Assoc. 1991, 86:108-113.[11]Pepe, M. S., Reilly, M., Fleming, T. R., Auxiliary outcome data and the mean score method, J. Statist. Plan.Inference, 1994, 42: 137-160.[12]Reilly, M., Pepe, M. S., A mean score method for missing and auxiliary covariate data in regression models,Biometrika, 1995, 82: 299-314.[13]Carroll, R. J., Knickerbocker, R. K., Wang, C. Y., Dimension reduction in a semiparametric regression model with errors in covariates, The Annals of Statistics, 1995, 23: 161-181.[14]Sepanski, J. H., Lee, L. F., Semiparametric estimation of nonlinear error-in-variables models

  5. Switching dynamics and linear response spectra of a driven one-dimensional nonlinear lattice containing an intrinsic localized mode.

    Science.gov (United States)

    Sato, M; Imai, S; Fujita, N; Shi, W; Takao, Y; Sada, Y; Hubbard, B E; Ilic, B; Sievers, A J

    2013-01-01

    An intrinsic localized mode (ILM) represents a localized vibrational excitation in a nonlinear lattice. Such a mode will stay in resonance as the driver frequency is changed adiabatically until a bifurcation point is reached, at which point the ILM switches and disappears. The dynamics behind switching in such a many body system is examined here through experimental measurements and numerical simulations. Linear response spectra of a driven micromechanical array containing an ILM were measured in the frequency region between two fundamentally different kinds of bifurcation points that separate the large amplitude ILM state from the two low amplitude vibrational states. Just as a natural frequency can be associated with a driven harmonic oscillator, a similar natural frequency has been found for a driven ILM via the beat frequency between it and a weak, tunable probe. This finding has been confirmed using numerical simulations. The behavior of this nonlinear natural frequency plays important but different roles as the two bifurcation points are approached. At the upper transition its frequency coalesces with the driver and the resulting bifurcation is very similar to the saddle-node bifurcation of a single driven Duffing oscillator, which is treated in an Appendix. The lower transition occurs when the four-wave mixing partner of the natural frequency of the ILM intersects the topmost extended band mode of the same symmetry. The properties of linear local modes associated with the driven ILM are also identified experimentally for the first time and numerically but play no role in these transitions.

  6. Enlarging the linear response range of velocity with optimum imaging parameters and modified data processing in laser speckle imaging

    Science.gov (United States)

    Qiu, Jianjun; Li, Pengcheng; Ul'yanov, Sergey S.; Zeng, Shaoqun; Luo, Qingming

    2008-02-01

    Laser speckle imaging (LSI) technique is considered as a promising method of accessing cerebral blood flow (CBF) of animals for its high spatiotemporal resolution and simplicity. It is important in LSI that optimum imaging parameters and limited noises should be confirmed to promote the imaging precision. We investigated in this paper different factors which may affect the imaging results with a moving white plate model, and then proposed a method of enlarging the linear response range of velocity. Through experiment, we proposed in our LSI system the optimum imaging parameters, including the numerical aperture and magnification of microscopy, the integration time, the gain mode of CCD camera. The average intensity was found optimum at about 800 counts out of 4096 grey level, which permits the highest contrast in our experiment. To eliminate the influence of uneven illumination, a direct current weight of 27 counts was subtracted during data processing. The result indicated that the relationship between measured velocity and the real one remained linear with R2 equaling to 0.99 throughout the scale of 80 mm/s.

  7. Switching dynamics and linear response spectra of a driven one-dimensional nonlinear lattice containing an intrinsic localized mode

    Science.gov (United States)

    Sato, M.; Imai, S.; Fujita, N.; Shi, W.; Takao, Y.; Sada, Y.; Hubbard, B. E.; Ilic, B.; Sievers, A. J.

    2013-01-01

    An intrinsic localized mode (ILM) represents a localized vibrational excitation in a nonlinear lattice. Such a mode will stay in resonance as the driver frequency is changed adiabatically until a bifurcation point is reached, at which point the ILM switches and disappears. The dynamics behind switching in such a many body system is examined here through experimental measurements and numerical simulations. Linear response spectra of a driven micromechanical array containing an ILM were measured in the frequency region between two fundamentally different kinds of bifurcation points that separate the large amplitude ILM state from the two low amplitude vibrational states. Just as a natural frequency can be associated with a driven harmonic oscillator, a similar natural frequency has been found for a driven ILM via the beat frequency between it and a weak, tunable probe. This finding has been confirmed using numerical simulations. The behavior of this nonlinear natural frequency plays important but different roles as the two bifurcation points are approached. At the upper transition its frequency coalesces with the driver and the resulting bifurcation is very similar to the saddle-node bifurcation of a single driven Duffing oscillator, which is treated in an Appendix. The lower transition occurs when the four-wave mixing partner of the natural frequency of the ILM intersects the topmost extended band mode of the same symmetry. The properties of linear local modes associated with the driven ILM are also identified experimentally for the first time and numerically but play no role in these transitions.

  8. Wheat Drought-Responsive Grain Proteome Analysis by Linear and Nonlinear 2-DE and MALDI-TOF Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Wu-Jun Ma

    2012-11-01

    Full Text Available A comparative proteomic analysis of drought-responsive proteins during grain development of two wheat varieties Kauz (strong resistance to drought stress and Janz (sensitive to drought stress was performed by using linear and nonlinear 2-DE and MALDI-TOF mass spectrometry technologies. Results revealed that the nonlinear 2-DE had much higher resolution than the linear 2-DE. A total of 153 differentially expressed protein spots were detected by both 2-DE maps, of which 122 protein spots were identified by MALDI-TOF and MALDI-TOF/TOF mass spectrometry. The identified differential proteins were mainly involved in carbohydrate metabolism (26%, detoxification and defense (23%, and storage proteins (17%. Some key proteins demonstrated significantly different expression patterns between the two varieties. In particular, catalase isozyme 1, WD40 repeat protein, LEA and alpha-amylase inhibitors displayed an upregulated expression pattern in Kauz, whereas they were downregulated or unchanged in Janz. Small and large subunit ADP glucose pyrophosphorylase, ascorbate peroxidase and G beta-like protein were all downregulated under drought stress in Janz, but had no expression changes in Kauz. Sucrose synthase and triticin precursor showed an upregulated expression pattern under water deficits in both varieties, but their upregulation levels were much higher in Kauz than in Janz. These differentially expressed proteins could be related to the biochemical pathways for stronger drought resistance of Kauz.

  9. Large Deformations of a Soft Porous Material

    Science.gov (United States)

    MacMinn, Christopher W.; Dufresne, Eric R.; Wettlaufer, John S.

    2016-04-01

    Compressing a porous material will decrease the volume of the pore space, driving fluid out. Similarly, injecting fluid into a porous material can expand the pore space, distorting the solid skeleton. This poromechanical coupling has applications ranging from cell and tissue mechanics to geomechanics and hydrogeology. The classical theory of linear poroelasticity captures this coupling by combining Darcy's law with Terzaghi's effective stress and linear elasticity in a linearized kinematic framework. Linear poroelasticity is a good model for very small deformations, but it becomes increasingly inappropriate for moderate to large deformations, which are common in the context of phenomena such as swelling and damage, and for soft materials such as gels and tissues. The well-known theory of large-deformation poroelasticity combines Darcy's law with Terzaghi's effective stress and nonlinear elasticity in a rigorous kinematic framework. This theory has been used extensively in biomechanics to model large elastic deformations in soft tissues and in geomechanics to model large elastoplastic deformations in soils. Here, we first provide an overview and discussion of this theory with an emphasis on the physics of poromechanical coupling. We present the large-deformation theory in an Eulerian framework to minimize the mathematical complexity, and we show how this nonlinear theory simplifies to linear poroelasticity under the assumption of small strain. We then compare the predictions of linear poroelasticity with those of large-deformation poroelasticity in the context of two uniaxial model problems: fluid outflow driven by an applied mechanical load (the consolidation problem) and compression driven by a steady fluid throughflow. We explore the steady and dynamical errors associated with the linear model in both situations, as well as the impact of introducing a deformation-dependent permeability. We show that the error in linear poroelasticity is due primarily to kinematic

  10. FPGA-based electrocardiography (ECG signal analysis system using least-square linear phase finite impulse response (FIR filter

    Directory of Open Access Journals (Sweden)

    Mohamed G. Egila

    2016-12-01

    Full Text Available This paper presents a proposed design for analyzing electrocardiography (ECG signals. This methodology employs highpass least-square linear phase Finite Impulse Response (FIR filtering technique to filter out the baseline wander noise embedded in the input ECG signal to the system. Discrete Wavelet Transform (DWT was utilized as a feature extraction methodology to extract the reduced feature set from the input ECG signal. The design uses back propagation neural network classifier to classify the input ECG signal. The system is implemented on Xilinx 3AN-XC3S700AN Field Programming Gate Array (FPGA board. A system simulation has been done. The design is compared with some other designs achieving total accuracy of 97.8%, and achieving reduction in utilizing resources on FPGA implementation.

  11. Haglund's Deformity

    Science.gov (United States)

    ... to follow the surgeon’s instructions for postsurgical care. Prevention To help prevent a recurrence of Haglund’s deformity: wear appropriate shoes; avoid shoes with a rigid heel back use arch supports or orthotic devices perform stretching exercises to prevent the Achilles tendon from tightening ...

  12. Hydrostatic and shear behavior of frictionless granular assemblies under different deformation conditions

    NARCIS (Netherlands)

    Imole, Olukayode Isaiah; Kumar, Nishant; Magnanimo, Vanessa; Luding, Stefan

    2013-01-01

    Stress- and structure-anisotropy (bulk) responses to various deformation modes are studied for dense packings of linearly elastic, frictionless, polydisperse spheres in the (periodic) triaxial box element test configuration. The major goal is to formulate a guideline for the procedure of how to cali

  13. Hydrostatic and shear behavior of frictionless granular assemblies under different deformation conditions

    NARCIS (Netherlands)

    Imole, O.I.; Kumar, N.; Magnanimo, V.; Luding, S.

    2013-01-01

    Stress- and structure-anisotropy (bulk) responses to various deformation modes are studied for dense packings of linearly elastic, frictionless, polydisperse spheres in the (periodic) triaxial box element test configuration. The major goal is to formulate a guideline for the procedure of how to cali

  14. Principal component analysis of the dynamic response measured by fMRI: a generalized linear systems framework.

    Science.gov (United States)

    Andersen, A H; Gash, D M; Avison, M J

    1999-07-01

    Principal component analysis (PCA) is one of several structure-seeking multivariate statistical techniques, exploratory as well as inferential, that have been proposed recently for the characterization and detection of activation in both PET and fMRI time series data. In particular, PCA is data driven and does not assume that the neural or hemodynamic response reaches some steady state, nor does it involve correlation with any pre-defined or exogenous experimental design template. In this paper, we present a generalized linear systems framework for PCA based on the singular value decomposition (SVD) model for representation of spatio-temporal fMRI data sets. Statistical inference procedures for PCA, including point and interval estimation will be introduced without the constraint of explicit hypotheses about specific task-dependent effects. The principal eigenvectors capture both the spatial and temporal aspects of fMRI data in a progressive fashion; they are inherently matched to unique and uncorrelated features and are ranked in order of the amount of variance explained. PCA also acts as a variation reduction technique, relegating most of the random noise to the trailing components while collecting systematic structure into the leading ones. Features summarizing variability may not directly be those that are the most useful. Further analysis is facilitated through linear subspace methods involving PC rotation and strategies of projection pursuit utilizing a reduced, lower-dimensional natural basis representation that retains most of the information. These properties will be illustrated in the setting of dynamic time-series response data from fMRI experiments involving pharmacological stimulation of the dopaminergic nigro-striatal system in primates.

  15. Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664

    Directory of Open Access Journals (Sweden)

    Yamaguchi David K

    2006-03-01

    Full Text Available Abstract Background Xylitol is a naturally occurring sugar substitute that has been shown to reduce the level of mutans streptococci in plaque and saliva and to reduce tooth decay. It has been suggested that the degree of reduction is dependent on both the amount and the frequency of xylitol consumption. For xylitol to be successfully and cost-effectively used in public health prevention strategies dosing and frequency guidelines should be established. This study determined the reduction in mutans streptococci levels in plaque and unstimulated saliva to increasing frequency of xylitol gum use at a fixed total daily dose of 10.32 g over five weeks. Methods Participants (n = 132 were randomized to either active groups (10.32 g xylitol/day or a placebo control (9.828 g sorbitol and 0.7 g maltitol/day. All groups chewed 12 pieces of gum per day. The control group chewed 4 times/day and active groups chewed xylitol gum at a frequency of 2 times/day, 3 times/day, or 4 times/day. The 12 gum pieces were evenly divided into the frequency assigned to each group. Plaque and unstimulated saliva samples were taken at baseline and five-weeks and were cultured on modified Mitis Salivarius agar for mutans streptococci enumeration. Results There were no significant differences in mutans streptococci level among the groups at baseline. At five-weeks, mutans streptococci levels in plaque and unstimulated saliva showed a linear reduction with increasing frequency of xylitol chewing gum use at the constant daily dose. Although the difference observed for the group that chewed xylitol 2 times/day was consistent with the linear model, the difference was not significant. Conclusion There was a linear reduction in mutans streptococci levels in plaque and saliva with increasing frequency of xylitol gum use at a constant daily dose. Reduction at a consumption frequency of 2 times per day was small and consistent with the linear-response line but was not statistically

  16. Integrable Deformations of T -Dual σ Models

    Science.gov (United States)

    Borsato, Riccardo; Wulff, Linus

    2016-12-01

    We present a method to deform (generically non-Abelian) T duals of two-dimensional σ models, which preserves classical integrability. The deformed models are identified by a linear operator ω on the dualized subalgebra, which satisfies the 2-cocycle condition. We prove that the so-called homogeneous Yang-Baxter deformations are equivalent, via a field redefinition, to our deformed models when ω is invertible. We explain the details for deformations of T duals of principal chiral models, and present the corresponding generalization to the case of supercoset models.

  17. One dimensional equivalent linear ground response analysis - A case study of collapsed Margalla Tower in Islamabad during 2005 Muzaffarabad Earthquake

    Science.gov (United States)

    Mahmood, Khalid; Rehman, Zia-ur-; Farooq, Khalid; Memon, Shazim Ali

    2016-07-01

    One dimensional equivalent linear ground response analysis was conducted in the Margalla Tower building in Islamabad, which collapsed during 2005 Muzaffarabad Earthquake. The analyses were conducted in DEEPSOIL software, without considering the effect of ground water table. The input subsoil data were selected from laboratory and field tests conducted for the site with bedrock at a depth of 21 m as per site condition. The field and laboratory testing data showed that the subsoil beneath the Tower site was silty clay to lean clay according to the unified soil classification system. Four different accelerograms with PGA values of 0.17 g, 0.15 g, 0.22 g and 0.21 g, compatible with the earthquake in the target area were applied at the bedrock. The surface response spectra showed that, except the Accelerogram-1 all other three were amplified near the fundamental period of the site. The analyses showed that different PGA values (0.26 g, 0.21 g, 0.36 g and 0.21 g) were produced at the surface which can be explained due to the difference in the Fourier amplitude of input accelerograms. Furthermore, the different input accelerograms produced a different shear strain and thus mobilized different shear strengths along the soil profile depth. Finally, the calculated response spectra of accelerograms were compared with the response spectra of Islamabad. The calculated spectral acceleration values were found to be higher than reported by the Building Code of Pakistan (0.16 g to 0.24 g).

  18. Calculation of atomic excitation energies by time-dependent density functional theory within a modified linear response.

    Science.gov (United States)

    Hu, Chunping; Sugino, Osamu; Tateyama, Yoshitaka

    2009-02-11

    Time-dependent density functional theory (TDDFT) has become a standard tool for investigation of electronic excited states. However, for certain types of electronic excitations, TDDFT is known to give systematically inaccurate results, which has been attributed to the insufficiency of conventional exchange-correlation functionals, such as the local density approximation (LDA). To improve TDDFT performance within LDA, a modified linear response (MLR) scheme was recently proposed, in which the responses from not only the ground state, but also the intermediate excited states are taken into account. This scheme was shown to greatly improve TDDFT performance on the prediction of Rydberg and charge-transfer excitation energies of molecules. Yet, for a validation of this TDDFT-MLR scheme for excitation energies, there remain issues to be resolved regarding Rydberg transitions of single atoms before going to larger systems. In the present work, we show an adapted algorithm to construct the intermediate excited states for rare-gas atoms. With the technique, Rydberg transition energies can be well decoded from LDA, as will also be shown in the application of the TDDFT-MLR scheme to other types of atoms.

  19. Calculation of the linear heat generation rates which violate the thermomechanical limit of plastic deformation of the fuel cladding in function of the burn up of a BWR fuel rod type; Calculo de las razones de generacion de calor lineal que violen el limite termomecanico de deformacion plastica de la camisa en funcion del quemado de una barra combustible tipo BWR

    Energy Technology Data Exchange (ETDEWEB)

    Lucatero, M.A.; Hernandez L, H. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: mal@nuclear.inin.mx

    2003-07-01

    The linear heat generation rates (LHGR) for a BWR type generic fuel rod, as function of the burnup that violate the thermomechanical limit of circumferential plastic deformation of the can (canning) in nominal operation in stationary state of the fuel rod are calculated. The evaluation of the LHGR in function of the burnt of the fuel, is carried out under the condition that the deformation values of the circumferential plastic deformation of the can exceeds in 0.1 the thermomechanical value operation limit of 1%. The results of the calculations are compared with the generation rates of linear operation heat in function of the burnt for this fuel rod type. The calculations are carried out with the FEMAXI-V and RODBURN codes. The results show that for exhibitions or burnt between 0 and 16,000 M Wd/tU a minimum margin of 160.8 W/cm exists among LHGR (439.6 W/cm) operation peak for the given fuel and maximum LHGR of the fuel (calculated) to reach 1.1% of circumferential plastic deformation of the can, for the peak factor of power of 1.40. For burnt of 20,000 MWd/tU and 60,000 MWd/tU exist a margin of 150.3 and 298.6 W/cm, respectively. (Author)

  20. Study of the Performance of an All-Optical Half-Adder Based on Three-Core Non-Linear Directional Fiber Coupler Under Delayed and Instantaneous Non-Linear Kerr Responses

    Science.gov (United States)

    Menezes, J. W. M.; Fraga, W. B.; Lima, F. T.; Guimarães, G. F.; Ferreira, A. C.; Lyra, M. L.; Sombra, A. S. B.

    2011-06-01

    Recently, much attention has been given to the influence of the relaxation process of the non-linear response, because the usual assumption of instantaneous non-linear response fails for ultra-short pulses, and additional contributions coming from non-linear dispersion and delayed non-linearity have to be taken into account. This article presents a numerical analysis of the symmetric planar and asymmetric planar three-core non-linear directional fiber couplers operating with a soliton pulse, where effects of both delayed and instantaneous non-linear Kerr responses are analyzed for implementation of an all-optical half-adder. To implement this all-optical half-adder, eight configurations were analyzed for the non-linear directional fiber coupler, with two symmetric and six asymmetric configurations. The half-adder is the key building block for many digital processing functions, such as shift register, binary counter, and serial parallel data converters. The optical coupler is an important component for applications in optical-fiber telecommunication systems and all integrated optical circuit because of its very high switching speeds. In this numerical simulation, the symmetric/asymmetric planar presents a structure with three cores in a parallel equidistant arrangement, three logical inputs, and two output energy. To prove the effectiveness of the theoretical model for generation of the all-optical half-adder, the best phase to be applied to the control pulse was sought, and a study was done of the extinction ratio level as a function of the Δ > parameter, the normalized time duration, and the Sum and Carry outputs of the (symmetric planar/asymmetric planar) non-linear directional fiber coupler. In this article, the interest is in transmission characteristics, extinction ratio level, normalized time duration, and pulse evolution along the non-linear directional fiber coupler. To compare the performance of the all-optical half-adders, the figure of merit of the

  1. Brittle Deformation in the Ordos Basin in response to the Mesozoic destruction of the North China Craton

    Science.gov (United States)

    Wang, Q.; Jiang, L.

    2012-12-01

    Craton is continental block that has been tectonically stable since at least Proterozoic. Some cratons, however, become unstable for some geodynamic reasons. The North China Craton (NCC) is an example. Structure geological, geochemical, and geophysical works have revealed that the NCC was destructed in Cretaceous and that lithosphere thickness beneath the eastern NCC were thinned by 120 km. The present study will focus on deformation of the western NCC, and to understand the effect of the Mesozoic destruction of the North China Craton (NCC). Structural partitioning of the Ordos Basin, which is located in the western NCC, from the eastern NCC occurred during the Mesozoic. Unlike the eastern NCC where many Cretaceous metamorphic core complexes developed, sedimentary cover of the NCC remains nearly horizontal and deformation is manifested by joint. We visited 216 sites of outcrops and got 1928 joints measurements, among which 270 from Jurassic sandstones, 1378 from the Upper Triassic sandstones, 124 from the Middle and Lower Triassic sandstones, and 156 from Paleozoic sandstones. In the interior of the Ordos Basin, joints developed quite well in the Triassic strata, while joints in the Jurassic stata developed weakly and no joint in the Cretaceous strata. The Mesozoic stratigraphic thickness are: 1000 meters for the Lower Triassic, the Middle Triassic sandstone with thickness of 800 meters, 3000 meters for the Upper Triassic, 4000 meters for the Jurassic, and 1100 meters for the Lower Cretaceous. The vertical difference in joint development might be related to the burying depth of the strata: the higher the strata, the smaller the lithostatic stress, and then the weaker the joint. Joints in all stratigraphic levels showed a similar strain direction with the sigma 1 (the maximum pressure stress) vertical and the sigma 3 (the minimum pressure stress) horizontal and running N-S. The unconformity below the Cretaceous further indicates that joints in Jurassic and Triassic

  2. Responses to rotating linear acceleration vectors considered in relation to a model of the otolith organs. [human oculomotor response to transverse acceleration stress

    Science.gov (United States)

    Benson, A. J.; Barnes, G. R.

    1973-01-01

    Human subjects were exposed to a linear acceleration vector that rotated in the transverse plane of the skull without angular counterrotation. Lateral eye movements showed a sinusoidal change in slow phase velocity and an asymmetry or bias in the same direction as vector rotation. A model is developed that attributes the oculomotor response to otolithic mechanisms. It is suggested that the bias component is the manifestation of torsion of the statoconial plaque relative to the base of the utricular macula and that the sinusoidal component represents the translational oscillation of the statoconia. The model subsumes a hypothetical neural mechanism which allows x- and y-axis accelerations to be resolved. Derivation of equations of motion for the statoconial plaque in torsion and translation, which take into account forces acting in shear and normal to the macula, yield estimates of bias and sinusoidal components that are in qualitative agreement with the diverse experimental findings.

  3. Non-Linear Relationships between Aflatoxin B1 Levels and the Biological Response of Monkey Kidney Vero Cells

    Directory of Open Access Journals (Sweden)

    Mendel Friedman

    2013-08-01

    Full Text Available Aflatoxin-producing fungi contaminate food and feed during pre-harvest, storage and processing periods. Once consumed, aflatoxins (AFs accumulate in tissues, causing illnesses in animals and humans. Most human exposure to AF seems to be a result of consumption of contaminated plant and animal products. The policy of blending and dilution of grain containing higher levels of aflatoxins with uncontaminated grains for use in animal feed implicitly assumes that the deleterious effects of low levels of the toxins are linearly correlated to concentration. This assumption may not be justified, since it involves extrapolation of these nontoxic levels in feed, which are not of further concern. To develop a better understanding of the significance of low dose effects, in the present study, we developed quantitative methods for the detection of biologically active aflatoxin B1 (AFB1 in Vero cells by two independent assays: the green fluorescent protein (GFP assay, as a measure of protein synthesis by the cells, and the microculture tetrazolium (MTT assay, as a measure of cell viability. The results demonstrate a non-linear dose-response relationship at the cellular level. AFB1 at low concentrations has an opposite biological effect to higher doses that inhibit protein synthesis. Additional studies showed that heat does not affect the stability of AFB1 in milk and that the Vero cell model can be used to determine the presence of bioactive AFB1 in spiked beef, lamb and turkey meat. The implication of the results for the cumulative effects of low amounts of AFB1 in numerous foods is discussed.

  4. Programming of combined deformation, pseudo-velocity,and pseudo-acceleration response spectrum based METLAB GUI%基于MATLAB的GUI三联反应谱的设计

    Institute of Scientific and Technical Information of China (English)

    袁棪; 马乐为; 宋林

    2012-01-01

    Important value and engineering significance of earthquake engineering based on combined Deformation,Pseudo-velocity,and Pseudo-acceleration response spectrum,With the three spectrum of relationship from the theoretically analysis the relationship of obtained three logarithmic coordinate, combined Deformation, Pseudo-velocity, and Pseudo-acceleration response spectrum of the visual interface use of the Nigam integral method of programming with MATLAB GUI,The interface is simple to operation and simply enter the appropriate parameters in the callback procedure,this saves computing time and programming,and thus for research on earthquake engineering can significantly improve the efficiency and economy,the example shows that this method has good applicability, which has made a better human-computer interaction.%基于三联反应谱在地震工程中具有重要的价值和工程意义,通过给出三种谱的关系式,从理论上分析得出三者的对数坐标关系,在MATLAB的GUI图形界面中采用Nigam积分方法编程三联反应谱可视化界面.该界面操作简捷,回调过程中只需输入相应参数,大大节省了计算时间和编程,因而用于地震工程研究可显著提高工作效率和经济性.所给算例表明该方法具有较好的适用性,并能更好地进行人机交互.

  5. Quantification of fluvial response to tectonic deformation in the Central Pontides, Turkey; inferences from OSL dating of fluvial terraces

    Science.gov (United States)

    McClain, Kevin; Yıldırım, Cengiz; Çiner, Attila; Akif Sarıkaya, M.; Şahin, Sefa; Özcan, Orkan; Güneç Kıyak, Nafiye; Öztürk, Tuǧba

    2017-04-01

    From Late Miocene to present, Anatolia's rapid counterclockwise movement, which increases in velocity towards the Hellenic Arc, has formed the North Anatolian Fault (NAF), a dextral transform fault along the Anatolia-Eurasia plate boundary and the northern margin of the Central Anatolian Plateau (CAP). A zone of transpression referred to as the Central Pontides exists between the broad restraining bend of the NAF and the Black Sea Basin, uplifting what is interpreted as a detached flower structure. Dating of Quaternary landforms in the eastern flank of the Central Pontides has helped to understand its recent deformation. However, in the western flank of the Central Pontides there is an absence of Quaternary studies, relatively quiet modern seismicity, and difficulties locating or observing fault scarps. This led us to use optically stimulated luminescence dating (OSL-dating) of fluvial terrace sediments and the study of geomorphic features to gain insight into the influence of climate and tectonics on landscape evolution of this area. In this area, the Filyos River crosses the Karabük Fault (reverse fault) and deeply incises a gorge through the Karabük Range before flowing towards the Black Sea. In the gorge an abundance of indicators of tectonic deformation were mapped, such as hanging valleys, wind gaps, bedrock gorges, landslides, steep V-shaped channels, tilted basins, as well as fluvial strath terraces. In particular, strath terraces of at least 8 levels within just 1.5 km of horizontal distance were examined. We used OSL-dating to estimate five deposition ages of fluvial strath terrace sediments, leading to an estimation of incision and uplift rates over time. Using three samples per terrace with strath elevations of 246 ± 0.2 m, 105.49 ± 0.2 m, 43.6 ± 0.2 m, 15.3 ± 0.2 m and 3.6 ± 0.2 m above the Filyos River, we determined corresponding ages of 841 ± 76 ka, 681 ± 49 ka, 386 ± 18 ka, 88 ± 5.1 ka and 50.9 ± 2.8 ka. Incision rates over time (oldest

  6. Role of non-linear oceanic processes in the response to westerly wind events: New implications for the 1997 El Niño onset

    Science.gov (United States)

    Boulanger, J.-P.; Durand, E.; Duvel, J.-P.; Menkes, C.; Delecluse, P.; Imbard, M.; Lengaigne, M.; Madec, G.; Masson, S.

    In March 1997, a strong westerly wind event (WWE) occurred in the western equatorial Pacific prior to the 1997-1998 El Niño event. It produced downwelling Kelvin waves that interacted non linearly with the surface temperature, salinity and zonal current fronts located at the eastern edge of the warm-fresh pool (EEWP). This non-linear interaction locally increased zonal currents by a factor of three compared to a theoretical linear response, and advected the EEWP at an unexpected rate (˜ 1m/s) to which the ocean-atmosphere coupled system may have been responding rapidly to trigger El Nino conditions.

  7. Complementary energy principle for large elastic deformation

    Institute of Scientific and Technical Information of China (English)

    GAO; Yuchen

    2006-01-01

    Using the "base forces" as the fundamental unknowns to determine the state of an elastic system, the complementary energy principle for large elastic deformation is constructed for the conjugate quantities being displacement gradients, which possesses exactly the same form as that of classical linear elasticity. It is revealed that the complementary energy contains deformation part and rotation part.

  8. Non-linear optical response of an impurity in a cylindrical quantum dot under the action of a magnetic field

    Science.gov (United States)

    Portacio, Alfonso A.; Rodríguez, Boris A.; Villamil, Pablo

    2017-04-01

    The linear and nonlinear optical response in a cylindrical quantum dot (CQD) of GaAs / Ga0.6Al0.4 As with a donor impurity in a uniform magnetic field applied in the axial direction of the cylinder is studied theoretically. The calculations were carried out in approximations of effective mass and two-level quantum systems. Using the variational method, the binding energies and the wave functions of the 1s-like y 2pz-like states for different positions of the impurity inside the CQD were found. It was found that the binding energy is greatest in the center of the CQD and diminishes as the impurity moves radially and/or axially. The optical rectification, the change in the refractive index, and the optical absorption were studied as functions of the energy of a photon incident on the CQD and different intensities of the magnetic field, with an impurity located at various positions. It was found that in a CDQ with an impurity inside, the effect of the variation of the intensity of the magnetic field on the optical response is much less than the effect produced by the variation of the position of the impurity. The physical reason for this behavior is that in nanostructures with impurities the Coulomb confinement is stronger than the magnetic confinement. It was also found that when the impurity is in the center of the quantum dot, the optical rectification coefficient is zero, due to the symmetry that the wave function of the impurity exhibits at this geometric point. When the impurity moves in the axial direction, the symmetry is broken and the optical rectification coefficient is different from zero, and its value increases as the impurity moves away from the center of the CQD.

  9. Reappraisal of nuclear quadrupole moments of atomic halogens via relativistic coupled cluster linear response theory for the ionization process.

    Science.gov (United States)

    Chaudhuri, Rajat K; Chattopadhyay, Sudip; Mahapatra, Uttam Sinha

    2013-11-27

    The coupled cluster based linear response theory (CCLRT) with four-component relativistic spinors is employed to compute the electric field gradients (EFG) of (35)Cl, (79)Br, and (127)I nuclei. The EFGs resulting from these calculations are combined with experimental nuclear quadrupole coupling constants (NQCC) to determine the nuclear quadrupole moments (NQM), Q of the halide nuclei. Our estimated NQMs [(35)Cl = -81.12 mb, (79)Br = 307.98 mb, and (127)I = -688.22 mb] agree well with the new atomic values [(35)Cl = -81.1(1.2), (79)Br = 302(5), and (127)I = -680(10) mb] obtained via Fock space multireference coupled cluster method with the Dirac-Coulomb-Breit Hamiltonian. Although our estimated Q((79)Br) value deviates from the accepted reference value of 313(3) mb, it agrees well with the recently recommended value, Q((79)Br) = 308.7(20) mb. Good agreement with current reference data indicates the accuracy of the proposed value for these halogen nuclei and lends credence to the results obtained via CCLRT approach. The electron affinities yielded by this method with no extra cost are also in good agreement with experimental values, which bolster our belief that the NQMs values for halogen nuclei derived here are reliable.

  10. Linear Response Equilibrium versus echo-planar encoding for fast high-spatial resolution 3D chemical shift imaging

    Science.gov (United States)

    Fischer, Rudolf Fritz; Baltes, Christof; Weiss, Kilian; Pazhenkottil, Aju; Rudin, Markus; Boesiger, Peter; Kozerke, Sebastian

    2011-07-01

    In this work Linear Response Equilibrium (LRE) and Echo-planar spectroscopic imaging (EPSI) are compared in terms of sensitivity per unit time and power deposition. In addition an extended dual repetition time scheme to generate broad stopbands for improved inherent water suppression in LRE is presented. The feasibility of LRE and EPSI for assessing cholesterol esters in human carotid plaques with high spatial resolution of 1.95 × 1.15 × 1.15 mm 3 on a clinical 3T MR system is demonstrated. In simulations and phantom experiments it is shown that LRE has comparable but lower sensitivity per unit time relative to EPSI despite stronger signal generated. This relates to the lower sampling efficiency in LRE relative to EPSI as a result of limited gradient performance on clinical MR systems. At the same time, power deposition of LRE is significantly reduced compared to EPSI making it an interesting niche application for in vivo high field spectroscopic imaging of metabolites within a limited bandwidth.

  11. Linear response of heat conductivity of normal-superfluid interface of a polarized Fermi gas to orbital magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Ebrahimian, N., E-mail: n.ebrahimian@aut.ac.ir [Physics Department, Amirkabir University of Technology, Tehran 15914 (Iran, Islamic Republic of); Mehrafarin, M., E-mail: mehrafar@aut.ac.ir [Physics Department, Amirkabir University of Technology, Tehran 15914 (Iran, Islamic Republic of); Afzali, R., E-mail: afzali@kntu.ac.ir [Physics Department, K.N. Toosi University of Technology, Tehran 15418 (Iran, Islamic Republic of)

    2012-01-01

    Using perturbed Bogoliubov equations, we study the linear response to a weak orbital magnetic field of the heat conductivity of the normal-superfluid interface of a polarized Fermi gas at sufficiently low temperature. We consider the various scattering regions of the BCS regime and analytically obtain the transmission coefficients and the heat conductivity across the interface in an arbitrary weak orbital field. For a definite choice of the field, we consider various values of the scattering length in the BCS range and numerically obtain the allowed values of the average and species-imbalance chemical potentials. Thus, taking Andreev reflection into account, we describe how the heat conductivity is affected by the field and the species imbalance. In particular, we show that the additional heat conductivity due to the orbital field increases with the species imbalance, which is more noticeable at higher temperatures. Our results indicate how the heat conductivity may be controlled, which is relevant to sensitive magnetic field sensors/regulators at the interface.

  12. Advantages of formulating an evolution equation directly for elastic distortional deformation in finite deformation plasticity

    Science.gov (United States)

    Rubin, M. B.; Cardiff, P.

    2017-06-01

    Simo (Comput Methods Appl Mech Eng 66:199-219, 1988) proposed an evolution equation for elastic deformation together with a constitutive equation for inelastic deformation rate in plasticity. The numerical algorithm (Simo in Comput Methods Appl Mech Eng 68:1-31, 1988) for determining elastic distortional deformation was simple. However, the proposed inelastic deformation rate caused plastic compaction. The corrected formulation (Simo in Comput Methods Appl Mech Eng 99:61-112, 1992) preserves isochoric plasticity but the numerical integration algorithm is complicated and needs special methods for calculation of the exponential map of a tensor. Alternatively, an evolution equation for elastic distortional deformation can be proposed directly with a simplified constitutive equation for inelastic distortional deformation rate. This has the advantage that the physics of inelastic distortional deformation is separated from that of dilatation. The example of finite deformation J2 plasticity with linear isotropic hardening is used to demonstrate the simplicity of the numerical algorithm.

  13. Charge-resonance excitations in symmetric molecules - Comparison of linear response DFT with CC3 for the excited states of a model dimer

    DEFF Research Database (Denmark)

    Kuhlman, Thomas Scheby; Mikkelsen, Kurt V.; Møller, Klaus Braagaard;

    2009-01-01

    We present a study on the excited states of an ethylene dimer as to investigate the presence of and perturbation from low-lying charge-resonance states calculated by linear response density functional theory (DFT) using the B3LYP and CAM-B3LYP functionals. The calculations are compared to a refer......We present a study on the excited states of an ethylene dimer as to investigate the presence of and perturbation from low-lying charge-resonance states calculated by linear response density functional theory (DFT) using the B3LYP and CAM-B3LYP functionals. The calculations are compared...

  14. On the potential importance of non-linear viscoelastic material modelling for numerical prediction of brain tissue response: test and application.

    Science.gov (United States)

    Brands, Dave W A; Bovendeerd, Peter H M; Wismans, Jac S H M

    2002-11-01

    In current Finite Element (FE) head models, brain tissue is commonly assumed to display linear viscoelastic material behaviour. However, brain tissue behaves like a non-linear viscoelastic solid for shear strains above 1%. The main objective of this study was to study the effect of non-linear material behaviour on the predicted brain response. We used a non-linear viscoelastic constitutive model, developed on the basis of experimental shear data presented elsewere. First we tested the numerical implementation of the constitutive model by simulating the response of a silicone gel (Sylgard 572 A&B) filled cylindrical cup, subjected to a transient rotational acceleration. The experimental results could be reproduced within 9%. Subsequently, the effect of non-linear material modelling on computed brain response was investigated in an existing three-dimensional head model subjected to an eccentric rotation. At the applied external load strains in the brain were approximately ten times larger than was expected on the basis of published data. This is probably caused by the values of the shear moduli applied in the model. These are at least a factor of ten lower than the ones used in head models in literature but comparable to material data in recent literature. Non-linear material behaviour was found to influence the levels of predicted strains (+20%) and stresses (-11%) but not their temporal and spatial distribution. The pressure response was independent of non-linear material behaviour. In fact it could be predicted by the equilibrium of momentum, and thus it is independent of the choice of the brain constitutive model.

  15. Utilization of the Generalized Method of Cells to Analyze the Deformation Response of Laminated Ceramic Matrix Composites

    Science.gov (United States)

    Goldberg, Robert K.

    2012-01-01

    In order to practically utilize ceramic matrix composites in aircraft engine components, robust analysis tools are required that can simulate the material response in a computationally efficient manner. The MAC/GMC software developed at NASA Glenn Research Center, based on the Generalized Method of Cells micromechanics method, has the potential to meet this need. Utilizing MAC/GMC, the effective stiffness properties, proportional limit stress and ultimate strength can be predicted based on the properties and response of the individual constituents. In this paper, the effective stiffness and strength properties for a representative laminated ceramic matrix composite with a large diameter fiber are predicted for a variety of fiber orientation angles and laminate orientations. As part of the analytical study, methods to determine the in-situ stiffness and strength properties of the constituents required to appropriately simulate the effective composite response are developed. The stiffness properties of the representative composite have been adequately predicted for all of the fiber orientations and laminate configurations examined in this study. The proportional limit stresses and strains and ultimate stresses and strains were predicted with varying levels of accuracy, depending on the laminate orientation. However, for the cases where the predictions did not have the desired level of accuracy, the specific issues related to the micromechanics theory were identified which could lead to difficulties that were encountered that could be addressed in future work.

  16. Linear analysis of the 4-step Carr\\'e phase shifting algorithm: spectrum, signal-to-noise ratio, and harmonics response

    CERN Document Server

    Servin, Manuel

    2012-01-01

    We analyze the nonlinear Carr\\'e 4-steps algorithm including its frequency response, signal-to-noise ratio, and harmonics rejection using linear systems theory. At first sight the previous statement as well as the title of this paper seems paradoxical. How can we analyze the 4-step non-linear Carr\\'e Phase Shifting Algorithm (PSA) using linear system theory? The short answer is that the non-linear Carr\\'e algorithm may be decomposed into two building blocks. The first block is a tunable linear 4-step PSA, and the second one is a non-linear phase-step estimator. Although this fact is well known from the derivation of the Carr\\'e algorithm, nobody has properly exploited it. In other words, to this day, we do not have explicit mathematical formulae for a) the spectrum, b) the harmonics rejection, and c) the signal-to-noise ratio of the non-linear Carr\\'e algorithm. These are the properties of the Carr\\'e's PSA that we show here with novel and explicit mathematical formulae.

  17. Yield response of winter wheat cultivars to environments modeled by different variance-covariance structures in linear mixed models

    Energy Technology Data Exchange (ETDEWEB)

    Studnicki, M.; Mądry, W.; Noras, K.; Wójcik-Gront, E.; Gacek, E.

    2016-11-01

    The main objectives of multi-environmental trials (METs) are to assess cultivar adaptation patterns under different environmental conditions and to investigate genotype by environment (G×E) interactions. Linear mixed models (LMMs) with more complex variance-covariance structures have become recognized and widely used for analyzing METs data. Best practice in METs analysis is to carry out a comparison of competing models with different variance-covariance structures. Improperly chosen variance-covariance structures may lead to biased estimation of means resulting in incorrect conclusions. In this work we focused on adaptive response of cultivars on the environments modeled by the LMMs with different variance-covariance structures. We identified possible limitations of inference when using an inadequate variance-covariance structure. In the presented study we used the dataset on grain yield for 63 winter wheat cultivars, evaluated across 18 locations, during three growing seasons (2008/2009-2010/2011) from the Polish Post-registration Variety Testing System. For the evaluation of variance-covariance structures and the description of cultivars adaptation to environments, we calculated adjusted means for the combination of cultivar and location in models with different variance-covariance structures. We concluded that in order to fully describe cultivars adaptive patterns modelers should use the unrestricted variance-covariance structure. The restricted compound symmetry structure may interfere with proper interpretation of cultivars adaptive patterns. We found, that the factor-analytic structure is also a good tool to describe cultivars reaction on environments, and it can be successfully used in METs data after determining the optimal component number for each dataset. (Author)

  18. Yield response of winter wheat cultivars to environments modeled by different variance-covariance structures in linear mixed models

    Directory of Open Access Journals (Sweden)

    Marcin Studnicki

    2016-06-01

    Full Text Available The main objectives of multi-environmental trials (METs are to assess cultivar adaptation patterns under different environmental conditions and to investigate genotype by environment (G×E interactions. Linear mixed models (LMMs with more complex variance-covariance structures have become recognized and widely used for analyzing METs data. Best practice in METs analysis is to carry out a comparison of competing models with different variance-covariance structures. Improperly chosen variance-covariance structures may lead to biased estimation of means resulting in incorrect conclusions. In this work we focused on adaptive response of cultivars on the environments modeled by the LMMs with different variance-covariance structures. We identified possible limitations of inference when using an inadequate variance-covariance structure. In the presented study we used the dataset on grain yield for 63 winter wheat cultivars, evaluated across 18 locations, during three growing seasons (2008/2009-2010/2011 from the Polish Post-registration Variety Testing System. For the evaluation of variance-covariance structures and the description of cultivars adaptation to environments, we calculated adjusted means for the combination of cultivar and location in models with different variance-covariance structures. We concluded that in order to fully describe cultivars adaptive patterns modelers should use the unrestricted variance-covariance structure. The restricted compound symmetry structure may interfere with proper interpretation of cultivars adaptive patterns. We found, that the factor-analytic structure is also a good tool to describe cultivars reaction on environments, and it can be successfully used in METs data after determining the optimal component number for each dataset.

  19. Linear and nonlinear characteristics of the runoff response to regional climate factors in the Qira River basin, Xinjiang, Northwest China.

    Science.gov (United States)

    Xue, Jie; Gui, Dongwei

    2015-01-01

    The inland river watersheds of arid Northwest China represent an example of how, in recent times, climatic warming has increased the complexity of Earth's hydrological processes. In the present study, the linear and nonlinear characteristics of the runoff response to temperature and precipitation were investigated in the Qira River basin, located on the northern slope of the Kunlun Mountains. The results showed that average temperature on annual and seasonal scales has displayed a significantly increasing trend, but this has not been reflected in accumulated precipitation and runoff. Using path analysis, a positive link between precipitation and runoff was found both annually and in the summer season. Conversely, it was found that the impact of temperature on runoff has been negative since the 1960s, attributable to higher evaporation and infiltration in the Qira River basin. Over the past 50 years, abrupt changes in annual temperature, precipitation and runoff occurred in 1997, 1987 and 1995, respectively. Combined with analysis using the correlation dimension method, it was found that the temperature, precipitation and runoff, both annually and seasonally, possessed chaotic dynamic characteristics, implying that complex hydro-climatic processes must be introduced into other variables within models to describe the dynamics. In addition, as determined via rescaled range analysis, a consistent annual and seasonal decreasing trend in runoff under increasing temperature and precipitation conditions in the future should be taken into account. This work may provide a theoretical perspective that can be applied to the proper use and management of oasis water resources in the lower reaches of river basins like that of the Qira River.

  20. Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway.

    Science.gov (United States)

    Vargas, Patrick D; Furuyama, Kazumichi; Sassa, Shigeru; Shibahara, Shigeki

    2008-12-01

    Heme is synthesized in all cell types in aerobic organisms. Hydroxymethylbilane synthase (HMBS) and uroporphyrinogen III synthase (UROS) catalyze two consecutive reactions in the heme biosynthetic pathway, generating the first linear and the first cyclic tetrapyrroles, respectively. Each of the HMBS and UROS genes contains the two separate promoters that generate ubiquitous and erythroid-specific mRNAs. Despite the functional significance of HMBS and UROS, regulation of their gene expression remains to be investigated. Here, we showed that hypoxia (1% O(2)) decreased the expression of ubiquitous mRNAs for HMBS and UROS by three- and twofold, respectively, in human hepatic cells (HepG2 and Hep3B), whereas the expression of ubiquitous and erythroid HMBS and UROS mRNAs remained unchanged in erythroid cells (YN-1 and K562). Unexpectedly, hypoxia did not decrease the half-life of HMBS mRNA (8.4 h under normoxia versus 9.1 h under hypoxia) or UROS mRNA (9.0 versus 10.4 h) in hepatic cells. It is therefore unlikely that a change in mRNA stability is responsible for the hypoxia-mediated decrease in the expression levels of these mRNAs. Furthermore, expression levels of HMBS and UROS mRNAs were decreased under normoxia by treatment with deferoxamine or cobalt chloride in hepatic cells, while hypoxia-inducible factor 1alpha was accumulated. Thus, the decrease in the expression of ubiquitous HMBS and UROS mRNAs is associated with accumulation of hypoxia-inducible factor 1alpha protein. In conclusion, the expression of HMBS and UROS mRNAs may be coordinately regulated, which represents a newly identified mechanism that is important for heme homeostasis.

  1. Nested generalized linear mixed model with ordinal response: Simulation and application on poverty data in Java Island

    Science.gov (United States)

    Widyaningsih, Yekti; Saefuddin, Asep; Notodiputro, Khairil A.; Wigena, Aji H.

    2012-05-01

    The objective of this research is to build a nested generalized linear mixed model using an ordinal response variable with some covariates. There are three main jobs in this paper, i.e. parameters estimation procedure, simulation, and implementation of the model for the real data. At the part of parameters estimation procedure, concepts of threshold, nested random effect, and computational algorithm are described. The simulations data are built for 3 conditions to know the effect of different parameter values of random effect distributions. The last job is the implementation of the model for the data about poverty in 9 districts of Java Island. The districts are Kuningan, Karawang, and Majalengka chose randomly in West Java; Temanggung, Boyolali, and Cilacap from Central Java; and Blitar, Ngawi, and Jember from East Java. The covariates in this model are province, number of bad nutrition cases, number of farmer families, and number of health personnel. In this modeling, all covariates are grouped as ordinal scale. Unit observation in this research is sub-district (kecamatan) nested in district, and districts (kabupaten) are nested in province. For the result of simulation, ARB (Absolute Relative Bias) and RRMSE (Relative Root of mean square errors) scale is used. They show that prov parameters have the highest bias, but more stable RRMSE in all conditions. The simulation design needs to be improved by adding other condition, such as higher correlation between covariates. Furthermore, as the result of the model implementation for the data, only number of farmer family and number of medical personnel have significant contributions to the level of poverty in Central Java and East Java province, and only district 2 (Karawang) of province 1 (West Java) has different random effect from the others. The source of the data is PODES (Potensi Desa) 2008 from BPS (Badan Pusat Statistik).

  2. Responses and toxin bioaccumulation in duckweed (Lemna minor) under microcystin-LR, linear alkybenzene sulfonate and their joint stress.

    Science.gov (United States)

    Wang, Zhi; Xiao, Bangding; Song, Lirong; Wang, Chunbo; Zhang, Junqian

    2012-08-30

    Microcystin-LR (MCLR) and linear alkylbenzene sulfonate (LAS) are commonly found in eutrophic lakes due to toxic cyanobacterial blooms and exogenous organic compounds pollution. However, the ecotoxicological risk of their combination in the aquatic environment is unknown. This study investigated the effects of MCLR, LAS and their mixture on duckweed (Lemna minor) growth and physiological responses. MCLR accumulation in duckweed, with or without LAS, was also examined. Growth of duckweed and chlorophyll-a contents were significantly reduced after 8d exposure to high concentrations of MCLR (≥ 3 μg/ml), LAS (≥ 20 μg/ml) and their mixture (≥ 3+10 μg/ml). After 2d of exposure, superoxide dismutase activity and glutathione content in duckweed increased with increasing concentrations of MCLR, LAS and their mixture, with a significant difference observable after 8d of exposure. When MCLR and LAS concentrations were lower (≤ 0.1+1 μg/ml), the interaction of them is synergistic, but when the concentrations were higher, the synergy was weak. MC accumulation was much higher at 2d than at 8d when duckweed was exposed to lower concentrations of MCLR (≤ 3 μg/ml) or MCLR-LAS (≤ 3+10 μg/ml). Furthermore, LAS significantly enhanced the accumulation of MCLR in duckweed, even with LAS concentrations as low as 0.3 μg/ml (environmental concentration), indicating that greater negative ecological risks and higher MCLR phytoremediation potentials of duckweed might occur in MCLR-LAS-concomitant water.

  3. Integration of aquatic fate and ecological responses to linear alkyl benzene sulfonate (LAS) in model stream ecosystems.

    Science.gov (United States)

    Belanger, S E; Bowling, J W; Lee, D M; LeBlanc, E M; Kerr, K M; McAvoy, D C; Christman, S C; Davidson, D H

    2002-06-01

    An integrated model stream ecosystem fate and effect study of dodecyl linear alkylbenzene sulfonate (C(12)LAS) was performed in the summer and fall of 1996. The study addressed responses of periphytic microbes, immature benthic fauna including abundance, drift, and emergence of adult insects in a 56-day exposure. Exposures ranged from 126 to 2978 microg/L and were continuously presented in a single-pass, flow-through test system. Microbial heterotrophs acclimated to C(12)LAS exposure quickly (14 days) and biodegraded C(12)LAS at all concentrations. Blue-green algae responded by increasing in abundance with increasing C(12)LAS concentration. Invertebrates responded by increased drift and reduced benthic abundances at concentrations exceeding 293 microg/L. Emergence at 927 microg/L also declined relative to the control. Adverse responses for mayflies and chironomids were indicated using univariate statistical techniques. Multivariate techniques indicated these taxa plus mollusks, aquatic worms, caddisflies, and stoneflies were impaired at some concentrations. Bioavailability of C(12)LAS was investigated in streams as a function of the total suspended solid load in the water column driven by local weather and watershed patterns. A continuous bioavailability model indicated exposure was reduced by an average of 8.5+/-8.9%. A model ecosystem no-observed-effect concentration (NOEC) was concluded to be 293 microg/L based on measured water column exposure and adjusted to 268 microg/L by the bioavailability model. A literature review of 13 available model ecosystem studies was conducted and NOEC conclusions were adjusted by a structure-activity relationship to a dodecyl chain length (sulfophenyl position and distribution being ignored due to lack of information in the reviewed studies). Lentic studies (n=7) were found to have higher NOECs than lotic studies (n=6) and were more variable. Mean NOECs+/-SD for all studies, lentic studies only, and lotic studies only were 3320

  4. On the thermocapillary motion of deformable droplets

    CERN Document Server

    Berejnov, V V

    2001-01-01

    In studies on Marangoni type motion of particles the surface tension is often approximated as a linear function of temperature. For deformable particles in a linear external temperature gradient far from the reference point this approximation yields a negative surface tension which is physically unrealistic. It is shown that H.Zhou and R.H.Davis J. Colloid Interface Sci., n.181,60,1996 presented calculation where the leading deformable drop moved into a region of negative surface tension. With respect numerical studies the restriction of the migration of two deformable drops is given in terms of the drift time.

  5. Characterization of the earwig, Doru lineare, as a predator of larvae of the fall armyworm, Spodoptera frugiperda: a functional response study.

    Science.gov (United States)

    Sueldo, Mabel Romero; Bruzzone, Octavio A; Virla, Eduardo G

    2010-01-01

    Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) is considered as the most important pest of maize in almost all tropical America. In Argentina, the earwig Doru lineare Eschscholtz (Dermaptera: Forficulidae) has been observed preying on S. frugiperda egg masses in corn crops, but no data about its potential role as a biocontrol agent of this pest have been provided. The predation efficiency of D. lineare on newly emerged S. frugiperda larva was evaluated through a laboratory functional response study. D. lineare showed type II functional response to S. frugiperda larval density, and disc equation estimations of searching efficiency and handling time were (a) = 0.374 and (t) = 182.9 s, respectively. Earwig satiation occurred at 39.4 S. frugiperda larvae.

  6. High dynamic range measurement of spectral responsivity and linearity of a radiation thermometer using a super-continuum laser and LEDs

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Y. S.; Lee, D. H.; Park, C. W.; Park, S. N. [Korea Research Institute of Standards and Science 209 Gajeong-Ro, Yuseong-Gu, Daejon 305-340 (Korea, Republic of)

    2013-09-11

    To realize the temperature scale above the freezing point of silver according to the definition of ITS-90, the dynamic range of the spectral responsivity is one of the most important factors which limit its uncertainty. When the residual spectral response at both side bands of a spectral band is not negligible, a significant uncertainty can be caused by a low dynamic range of the spectral responsivity measurement. In general, incandescent lamps are used to measure the spectral responsivity and the linearity. The dynamic range of the spectral responsivity measurement is often limited by a trade-off with the desired spectral resolution, which is less than 6 decades. Nonlinearity is another limiting fact of uncertainties of the temperature scale. Tungsten lamps have disadvantage in the nonlinearity measurements in terms of adjustability of radiance level and spectral selectivity. We report spectral responsivity measurements of which the measurable dynamic range is enhanced 50 times after replacing a QTH lamp with a super continuum laser. We also present a spectrally selected linearity measurement over a wide dynamic range using high-brightness light emitting diode arrays to observe a slight saturation of linearity.

  7. Mechanical response and deformation mechanisms of ferritic oxide dispersion strengthened steel structures produced by selective laser melting

    Energy Technology Data Exchange (ETDEWEB)

    Dryepondt, Sebastien N [ORNL; Boegelein, T [University of Liverpool, UK; Pandey, Amit [LGFCS; Dawson, K [University of Liverpool, UK; Tatlock, G.J. [University of Liverpool, UK

    2015-01-28

    Oxide dispersion strengthened (ODS) ferritic steels typically contain a fine dispersion of nanoscopic Y(Al, Ti) oxides, leading to an improvement in mechanical and physical properties. For a rapid prototyping technique, selective laser melting (SLM), was successfully applied to consolidate as-mechanically alloyed ODS-PM2000 (Fe 19Cr 5.5Al 0.5Ti 0.5Y2O3; all wt.%) powder to fabricate solid and thin-walled builds of different thickness. Our work is intended to act as a first study to investigate the tensile response of such configurations at room temperature, using miniaturized test specimens along and perpendicular to the growth direction. The 0.2% offset yield strength of as-grown wall builds was inferior to conventional PM2000 alloy (recrystallized), but could be significantly increased by conducting post-build heat treatments. Young s modulus and yield strength showed anisotropy and were enhanced when testing perpendicular to the build growth direction. Electron backscatter diffraction revealed a strong [001] fibre texture along the growth direction, which explains the anisotropic behaviour. In addition, studies on the morphology of the individual fracture surfaces, the grain structure of the cross-section near this region and the size distribution of ODS particles in such builds were conducted. A fine dispersion of precipitates was retained in all SLM builds, and findings suggest that a certain amount of Y is probably still in atomic solution in the as-grown condition and forms new small nanoscopic dispersoids during annealing, which lead to enhanced strengthening.

  8. Linearization Techniques

    Directory of Open Access Journals (Sweden)

    Gildeberto S. Cardoso

    2011-01-01

    Full Text Available This paper presents a study of linear control systems based on exact feedback linearization and approximate feedback linearization. As exact feedback linearization is applied, a linear controller can perform the control objectives. The approximate feedback linearization is required when a nonlinear system presents a noninvolutive property. It uses a Taylor series expansion in order to compute a nonlinear transformation of coordinates to satisfy the involutivity conditions.

  9. Ethylene signaling pathway is not linear, however its lateral part is responsible for sensing and signaling of sulfur status in plants.

    Science.gov (United States)

    Moniuszko, Grzegorz

    2015-01-01

    A secondary, non-linear, lateral part of ethylene signaling pathway has been anticipated and speculated before. Recently, it has been found that part of the proteomic response of Eruca sativa to silver nitrate (which is an inhibitor of ethylene signaling) is related to sulfur metabolism. Using public Arabidopsis thaliana microarray data, I show that silver nitrate mimics the signal of sulfur starvation at the transcriptome level. This, combined with data mined from literature, indicates that ethylene receptors are localized at the beginning of the response to sulfur deficiency in plants. This means that the non-linear, lateral part of ethylene signaling pathway exists and is responsible for transduction of the signal of sulfur deficit. Here, I present a model of such a pathway and anticipate it to be the starting point for more detailed analysis of the lateral part of ethylene signaling pathway and the exact mechanism of sulfur status sensing in plants.

  10. Ethylene signaling pathway is not linear, however its lateral part is responsible for sensing and signaling of sulfur status in plants

    Science.gov (United States)

    Moniuszko, Grzegorz

    2015-01-01

    A secondary, non-linear, lateral part of ethylene signaling pathway has been anticipated and speculated before. Recently, it has been found that part of the proteomic response of Eruca sativa to silver nitrate (which is an inhibitor of ethylene signaling) is related to sulfur metabolism. Using public Arabidopsis thaliana microarray data, I show that silver nitrate mimics the signal of sulfur starvation at the transcriptome level. This, combined with data mined from literature, indicates that ethylene receptors are localized at the beginning of the response to sulfur deficiency in plants. This means that the non-linear, lateral part of ethylene signaling pathway exists and is responsible for transduction of the signal of sulfur deficit. Here, I present a model of such a pathway and anticipate it to be the starting point for more detailed analysis of the lateral part of ethylene signaling pathway and the exact mechanism of sulfur status sensing in plants. PMID:26340594

  11. Deformed soft matter under constraints

    Science.gov (United States)

    Bertrand, Martin

    In the last few decades, an increasing number of physicists specialized in soft matter, including polymers, have turned their attention to biologically relevant materials. The properties of various molecules and fibres, such as DNA, RNA, proteins, and filaments of all sorts, are studied to better understand their behaviours and functions. Self-assembled biological membranes, or lipid bilayers, are also the focus of much attention as many life processes depend on these. Small lipid bilayers vesicles dubbed liposomes are also frequently used in the pharmaceutical and cosmetic industries. In this thesis, work is presented on both the elastic properties of polymers and the response of lipid bilayer vesicles to extrusion in narrow-channels. These two areas of research may seem disconnected but they both concern deformed soft materials. The thesis contains four articles: the first presenting a fundamental study of the entropic elasticity of circular chains; the second, a simple universal description of the effect of sequence on the elasticity of linear polymers such as DNA; the third, a model of the symmetric thermophoretic stretch of a nano-confined polymer; the fourth, a model that predicts the final sizes of vesicles obtained by pressure extrusion. These articles are preceded by an extensive introduction that covers all of the essential concepts and theories necessary to understand the work that has been done.

  12. The physician's breach of the duty to inform the parent of deformities and abnormalities in the foetus: "wrongful life" actions, a new frontier of medical responsibility.

    Science.gov (United States)

    Frati, Paola; Gulino, Matteo; Turillazzi, Emanuela; Zaami, Simona; Fineschi, Vittorio

    2014-07-01

    A recent decision of the Italian Highest Court for the first time legitimized wrongful life suits. The Court stated the following principles: (a) the contract between the mother and the doctor has also protective effects in favour of third parties (father, siblings and the disabled child) who have the right to be compensated; (b) the right to compensation is neither based on the right not to be born nor on the right to be born healthy, but rather it is based on the breach of duty of care which coincides with the child's disabled status; (c) siblings may suffer the reduced availability of their parents; (d) the doctor is held responsible for not providing full information to the mother about the foetal deformity. The Supreme Court once again emphasized the importance of information on the matter of very personal choices, such as termination of pregnancy in case of foetal malformations. In the present case, the gynaecologist breached the duty to inform, especially after the patient requested diagnostic tests designed to highlight any foetal malformations and informed the doctor of the possibility of an eventual subsequent termination of pregnancy if foetal malformations were found.

  13. On the Need for Comprehensive Validation of Deformable Image Registration, Investigated With a Novel 3-Dimensional Deformable Dosimeter

    Energy Technology Data Exchange (ETDEWEB)

    Juang, Titania [Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina (United States); Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina (United States); Das, Shiva [Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina (United States); Adamovics, John; Benning, Ron [Department of Chemistry and Biology, Rider University, Lawrenceville, New Jersey (United States); Oldham, Mark, E-mail: mark.oldham@duke.edu [Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina (United States)

    2013-10-01

    Purpose: To introduce and evaluate a novel deformable 3-dimensional (3D) dosimetry system (Presage-Def/Optical-CT) and its application toward investigating the accuracy of dose deformation in a commercial deformable image registration (DIR) package. Methods and Materials: Presage-Def is a new dosimetry material consisting of an elastic polyurethane matrix doped with radiochromic leuco dye. Radiologic and mechanical properties were characterized using standard techniques. Dose-tracking feasibility was evaluated by comparing dose distributions between dosimeters irradiated with and without 27% lateral compression. A checkerboard plan of 5-mm square fields enabled precise measurement of true deformation using 3D dosimetry. Predicted deformation was determined from a commercial DIR algorithm. Results: Presage-Def exhibited a linear dose response with sensitivity of 0.0032 ΔOD/(Gy∙cm). Mass density is 1.02 g/cm{sup 3}, and effective atomic number is within 1.5% of water over a broad (0.03-10 MeV) energy range, indicating good water-equivalence. Elastic characteristics were close to that of liver tissue, with Young's modulus of 13.5-887 kPa over a stress range of 0.233-303 kPa, and Poisson's ratio of 0.475 (SE, 0.036). The Presage-Def/Optical-CT system successfully imaged the nondeformed and deformed dose distributions, with isotropic resolution of 1 mm. Comparison with the predicted deformed 3D dose distribution identified inaccuracies in the commercial DIR algorithm. Although external contours were accurately deformed (submillimeter accuracy), volumetric dose deformation was poor. Checkerboard field positioning and dimension errors of up to 9 and 14 mm, respectively, were identified, and the 3D DIR-deformed dose γ passing rate was only γ{sub 3%/3} {sub mm} = 60.0%. Conclusions: The Presage-Def/Optical-CT system shows strong potential for comprehensive investigation of DIR algorithm accuracy. Substantial errors in a commercial DIR were found in the

  14. Geometrically nonlinear deformation and the emergent behavior of polarons in soft matter.

    Science.gov (United States)

    Li, Xiaobao; Liu, Liping; Sharma, Pradeep

    2015-11-07

    Mechanical strain can alter the electronic structure of both bulk semiconductors as well as nanostructures such as quantum dots. This fact has been extensively researched and exploited for tailoring electronic properties. The strain mediated interaction between the charge carriers and the lattice is interpreted through the so-called deformation potential. In the case of soft materials or nanostructures, such as DNA, the deformation potential leads to the formation of polarons which largely determine the electronic characteristics of DNA and similar polymer entities. In addition, polarons are also speculated to be responsible for the mechanism of quantum actuation in carbon nanotubes. The deformation potential is usually taken to be a linear function of the lattice deformation (U ∼ αε) where α is the deformation potential "constant" that determines the coupling strength and ε is the mechanical strain. In this letter, by carefully accounting for nonlinear geometric deformation that has been hitherto ignored so far in this context, we show that the deformation potential constant is renormalized in a non-trivial manner and is hardly a constant. It varies spatially within the material and with the size of the material. This effect, while negligible for hard materials, is found to be important for soft materials and critically impacts the interpretation of quantities such as polaron size, binding energy, and accordingly, electronic behavior.

  15. Deformed two center shell model

    CERN Document Server

    Gherghescu, R A

    2003-01-01

    A highly specialized two-center shell model has been developed accounting for the splitting of a deformed parent nucleus into two ellipsoidaly deformed fragments. The potential is based on deformed oscillator wells in direct correspondance with the shape change of the nuclear system. For the first time a potential responsible for the necking part between the fragments is introduced on potential theory basis. As a direct consequence, spin-orbit {\\bf ls} and {\\bf l$^2$} operators are calculated as shape dependent. Level scheme evolution along the fission path for pairs of ellipsoidaly deformed fragments is calculated. The Strutinsky method yields the shell corrections for different mass asymmetries from the superheavy nucleus $^{306}$122 and $^{252}$Cf all along the splitting process.

  16. Simulating the three-dimensional deformation of in vivo facial skin.

    Science.gov (United States)

    Flynn, Cormac; Taberner, Andrew J; Nielsen, Poul M F; Fels, Sidney

    2013-12-01

    Characterising the mechanical properties of human facial skin is a challenging but important endeavour with applications in biomedicine, surgery simulation, forensics, and animation. Many existing computer models of the face are not based on in vivo facial skin deformation data but rather on experiments using in vitro facial skin or other soft tissues. The facial skin of five volunteers was subjected to a rich set of deformations using a micro-robotic device. The force-displacement response was recorded for each deformation. All volunteers' facial skin exhibited a non-linear, anisotropic, and viscoelastic force-displacement response. We propose a finite element model that simulated the experimental deformations with error-of-fits ranging from 11% to 23%. The skin was represented by an Ogden strain energy function and a quasi-linear viscoelastic law. From non-linear optimisation procedures, we determined material parameters and in vivo pre-stresses for the central cheek area of five volunteers and five other facial points on one volunteer. Pre-stresses ranged from 15.9kPa to 89.4kPa.

  17. Linear algebra

    CERN Document Server

    Shilov, Georgi E

    1977-01-01

    Covers determinants, linear spaces, systems of linear equations, linear functions of a vector argument, coordinate transformations, the canonical form of the matrix of a linear operator, bilinear and quadratic forms, Euclidean spaces, unitary spaces, quadratic forms in Euclidean and unitary spaces, finite-dimensional space. Problems with hints and answers.

  18. Evaluation of the thermal-hydraulic response and fuel rod thermal and mechanical deformation behavior during the power burst facility test LOC-3. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Yackle, T.R.; MacDonald, P.E.; Broughton, J.M.

    1980-01-01

    An evaluation of the results from the LOC-3 nuclear blowdown test conducted in the Power Burst Facility is presented. The test objective was to examine fuel and cladding behavior during a postulated cold leg break accident in a pressurized water reactor (PWR). Separate effects of rod internal pressure and the degree of irradiation were investigated in the four-rod test. Extensive cladding deformation (ballooning) and failure occurred during blowdown. The deformation of the low and high pressure rods was similar; however, the previously irradiated test rod deformed to a greater extent than a similar fresh rod exposed to identical system conditions.

  19. TU-F-12A-03: Using 18F-FDG-PET-CT and Deformable Registration During Head-And-Neck Cancer (HNC) Intensity Modulated Radiotherapy (IMRT) to Predict Treatment Response

    Energy Technology Data Exchange (ETDEWEB)

    Vergalasova, I; Mowery, Y; Yoo, D; Brizel, D; Das, S [Duke University Medical Center, Durham, NC (United States)

    2014-06-15

    Purpose: To evaluate the effect of deformable vs. rigid registration of pre-treatment 18F-FDG-PET-CT to intra-treatment 18F-FDG-PET-CT on different standardized uptake value (SUV) parameters and investigate which parameters correlate best with post-treatment response in patients undergoing IMRT for HNC. Methods: Pre-treatment and intra-treatment PET-CT (after 20Gy) scans were acquired, in addition to a 12 week post-treatment PET-CT to assess treatment response. Primary and lymph node gross tumor volumes (GTV-PRI and GTV-LN) were contoured on the pre-treatment CT. These contours were then mapped to intra-treatment PET images via rigid and deformable registration. Absolute changes from pre- to intra-treatment scans for rigid and deformable registration were extracted for the following parameters: SUV-MAX, SUV-MEAN, SUV-20%, SUV-40%, and SUV-60% (SUV-X% is the minimum SUV to the highest-intensity X% volume). Results: Thirty-eight patients were evaluated, with 27 available for classification as complete or incomplete response (CR/ICR). The pre-treatment average tumor volumes for the patients were 24.05cm{sup 3} for GTV-PRI and 23.4cm{sup 3} for GTV-LN. For GTV-PRI, there was no statistically significant difference between rigid vs. deformable registration across all ΔSUV parameters. For GTV-LN contours, all parameters were significantly different except for ΔSUV-MAX. For deformably-registered GTV-PRI, changes in the following metrics were significantly different for CR vs. ICR: SUV-MEAN(p=0.003), SUV-20%(p=0.02), SUV-40%(p=0.02), and SUV-60%(p=0.008). The following cutoff values separated CR from ICR with high sensitivity and specificity: ΔSUV-MEAN=1.49, ΔSUV-20%=2.39, ΔSUV-40%=1.80 and ΔSUV-60%=1.31. Corresponding areas under the Receiver Operating Characteristics curve were 0.90, 0.81, 0.81, and 0.85, respectively. Conclusion: Rigidly and deformably registered contours yielded statistically similar SUV parameters for GTV-PRI, but not GTV-LN. This implies that

  20. Odd-parity currents induced by dynamic deformations in graphene-like systems

    Science.gov (United States)

    Zhang, Kai; Zhang, Erhu; Chen, Huawei; Zhang, Shengli

    2016-11-01

    Reduced (3  +  1)-dimensional Dirac systems with inter-pseudo-spin and inter-valley scattering are employed to investigate current responses to (chiral) gauge fields in graphene-like systems. From (chiral) current—(chiral) current correlation functions, we derive the current responses. Except for electric currents induced by external gauge fields, we find the inter-valley scattering can break the topological nature of odd-parity currents. Given the proper conditions, this property can help us realize valley-polarized electric currents. Through the dynamic deformations generating the chiral gauge fields, we find the vortex-like currents while their profiles can be tuned by superposition of some deformations. In particular, we find a more manageable approach to realize the topological electric current by choosing a linear dynamic deformation.

  1. Achieving a Linear Dose Rate Response in Pulse-Mode Silicon Photodiode Scintillation Detectors Over a Wide Range of Excitations

    Science.gov (United States)

    Carroll, Lewis

    2014-02-01

    We are developing a new dose calibrator for nuclear pharmacies that can measure radioactivity in a vial or syringe without handling it directly or removing it from its transport shield “pig”. The calibrator's detector comprises twin opposing scintillating crystals coupled to Si photodiodes and current-amplifying trans-resistance amplifiers. Such a scheme is inherently linear with respect to dose rate over a wide range of radiation intensities, but accuracy at low activity levels may be impaired, beyond the effects of meager photon statistics, by baseline fluctuation and drift inevitably present in high-gain, current-mode photodiode amplifiers. The work described here is motivated by our desire to enhance accuracy at low excitations while maintaining linearity at high excitations. Thus, we are also evaluating a novel “pulse-mode” analog signal processing scheme that employs a linear threshold discriminator to virtually eliminate baseline fluctuation and drift. We will show the results of a side-by-side comparison of current-mode versus pulse-mode signal processing schemes, including perturbing factors affecting linearity and accuracy at very low and very high excitations. Bench testing over a wide range of excitations is done using a Poisson random pulse generator plus an LED light source to simulate excitations up to ˜106 detected counts per second without the need to handle and store large amounts of radioactive material.

  2. Elasto-capillary collapse of floating structures - Non-linear response of elastic structures under capillary forces

    CERN Document Server

    Adami, N; Roman, B; Bico, J; Caps, H

    2013-01-01

    Flexible rings and rectangle structures floating at the surface of water are prone to deflect under the action of surface pressure induced by the addition of surfactant molecules on the bath. While the frames of rectangles bend inward or outward for any surface pressure difference, circles are only deformed by compression beyond a critical buckling load. However, compressed frames also undergo a secondary buckling instability leading to a rhoboidal shape. Following the pioneering works of \\cite{Hu} and \\cite{Zell}, we describe both experimentally and theoretically the different elasto-capillary deflection and buckling modes as a function of the material parameters. In particular we show how this original fluid structure interaction may be used to probe the adsorption of surfactant molecules at liquid interfaces.

  3. Performance of low-cost few-mode fiber Bragg grating sensor systems: polarization sensitivity and linearity of temperature and strain response

    DEFF Research Database (Denmark)

    Ganziy, Denis; Rose, Bjarke; Bang, Ole

    2016-01-01

    We evaluate whether 850 nm fiber Bragg grating (FBG) sensor systems can use low-cost 1550 nm telecom fibers; in other words, how detrimental the influence of higher-order modes is to the polarization stability and linearity of the strain and temperature response. We do this by comparing...... polarization sensitivity of a few-mode 850 nm FBG sensor to a strictly single-mode 850 nm FBG sensor system using 850 nm single-mode fibers. We also compare the performance of the FBGs in strain and temperature tests. Our results show that the polarization stability and the linearity of the response degrade...... due to the presence of the higher-order modes. We demonstrate that, by using simple coiling of the 1550 nm fiber, one can regain the performance of the few-mode system and make it usable for high precision measurements....

  4. A Linear Response DFT+U Study of Trends in the Oxygen Evolution Activity of Transition Metal Rutile Dioxides

    DEFF Research Database (Denmark)

    Xu, Zhongnan; Rossmeisl, Jan; Kitchin, John R.

    2015-01-01

    There are known errors in oxidation energies of transition metal oxides caused by an improper treatment of their d-electrons. The Hubbard U is the cornputationally cheapest addition one can use to capture correct reaction energies, but the specific Hubbard U oftentimes m-uSt.be empirically...... determined only when suitable experimental data exist. We evaluated the effect of addling a calculated, linear response U on the predicted adsorption energies, scaling relationships, and activity trends with respect to the oxygen evolution reaction for a set of transition metal dioxides. We find...... that applying a U greater than zero always causes adsorption energies to be more endothermic. Furthermore, the addition of the Hubbard U greater than zero does not break scaling relationships established without the Hubbard U. The addition of the calculated linear response U value produces shifts of different...

  5. Vibrational absorption spectra from vibrational coupled cluster damped linear response functions calculated using an asymmetric Lanczos algorithm

    DEFF Research Database (Denmark)

    Thomsen, Bo; Hansen, Mikkel Bo; Seidler, Peter

    2012-01-01

    We report the theory and implementation of vibrational coupled cluster (VCC) damped response functions. From the imaginary part of the damped VCC response function the absorption as function of frequency can be obtained, requiring formally the solution of the now complex VCC response equations....... The absorption spectrum can in this formulation be seen as a matrix function of the characteristic VCC Jacobian response matrix. The asymmetric matrix version of the Lanczos method is used to generate a tridiagonal representation of the VCC response Jacobian. Solving the complex response equations...... in the relevant Lanczos space provides a method for calculating the VCC damped response functions and thereby subsequently the absorption spectra. The convergence behaviour of the algorithm is discussed theoretically and tested for different levels of completeness of the VCC expansion. Comparison is made...

  6. Análisis de la Pérdida de Precisión en Codificadores Opticos Lineales por Deformación de la Retícula Grabada Analysis of the Precision Lost in Optical Linear Encoders as a Consequence of Reticule Deformation

    Directory of Open Access Journals (Sweden)

    Ignacio Alejandre

    2006-01-01

    Full Text Available Se analiza la pérdida de precisión en codificadores (encoders opticos lineales por deformación de la retícula grabada. Los encoders ópticos lineales basados en el efecto moiré de franja infinita incorporan una retícula grabada sobre la superficie de un vidrio. Las deformaciones que dicho vidrio puede experimentar influyen de forma directa en la homogeneidad de la retícula, bien con carácter local o de forma más extendida. Dichas deformaciones pueden ser producidas por montajes inapropiados o por la propia modificación de la estructura de la máquina, en la que el encoder va montado, en las condiciones de funcionamiento. En este trabajo se compara la pérdida de precisión que se produce en los dos estados más probables de flexión del vidrio. Los resultados muestran que en las dos situaciones analizadas la deformación de la retícula del vidrio correspondiente al caso de colocación de calzos traseros es unas tres veces mayor que la correspondiente al caso de colocación de calzos inferiores.An analysis is made of the loss of precision in optical linear encoders due to deformation of the engraved reticule. Optical linear encoders based on the moiré effect of infinite boundary incorporate a reticule etched on a glass surface. Potential deformations of this glass directly influence the homogeneity of the reticule, in a local or generalised character. These deformations can be caused by inappropriate assembly or as a consequence of modification by the structure of the machine in which the encoder is incorporated, during working conditions. This study compares the loss of precision which occurs under the most probable conditions of flexion of the glass. The results showed that in the two situations analyzed, the deformation of the glass from a rear position was three times greater in effect than that observed in the case of deformation from below.

  7. Fisher information matrix for nonlinear mixed effects multiple response models: evaluation of the appropriateness of the first order linearization using a pharmacokinetic/pharmacodynamic model.

    Science.gov (United States)

    Bazzoli, Caroline; Retout, Sylvie; Mentré, France

    2009-06-30

    We focus on the Fisher information matrix used for design evaluation and optimization in nonlinear mixed effects multiple response models. We evaluate the appropriateness of its expression computed by linearization as proposed for a single response model. Using a pharmacokinetic-pharmacodynamic (PKPD) example, we first compare the computation of the Fisher information matrix with approximation to one derived from the observed matrix on a large simulation using the stochastic approximation expectation-maximization algorithm (SAEM). The expression of the Fisher information matrix for multiple responses is also evaluated by comparison with the empirical information obtained through a replicated simulation study using the first-order linearization estimation methods implemented in the NONMEM software (first-order (FO), first-order conditional estimate (FOCE)) and the SAEM algorithm in the MONOLIX software. The predicted errors given by the approximated information matrix are close to those given by the information matrix obtained without linearization using SAEM and to the empirical ones obtained with FOCE and SAEM. The simulation study also illustrates the accuracy of both FOCE and SAEM estimation algorithms when jointly modelling multiple responses and the major limitations of the FO method. This study highlights the appropriateness of the approximated Fisher information matrix for multiple responses, which is implemented in PFIM 3.0, an extension of the R function PFIM dedicated to design evaluation and optimization. It also emphasizes the use of this computing tool for designing population multiple response studies, as for instance in PKPD studies or in PK studies including the modelling of the PK of a drug and its active metabolite.

  8. Dynamic Deformation of Thermosetting Polymers---All Atomistic Simulations

    Science.gov (United States)

    Tsige, Mesfin; Shenogina, Natalia; Mukhopadhyay, Sharmila; Patnaik, Soumya

    2013-03-01

    We are using all-atom molecular dynamics simulations to investigate the interconnection between structural and mechanical properties of highly cross-linked polymer networks. In this study we focused on the widely used resin-hardener system composed of DGEBA epoxy oligomers and aromatic amine hardener DETDA. Accurate cross-linked models were developed using the effective cross-linking procedure that enables to generate thermoset structures with realistic structural characteristics. These models were used to examine the elastic properties of thermosetting networks with various degrees of curing and length of resin strands both in glassy and rubbery states. In our recent study we employed static deformation approach to estimate potential energy contribution to the mechanical response. In the present work we are using dynamic deformation approach which takes into account both potential energy and thermal motions in the structure. Uniaxial, volumetric and shear dynamic deformation modes were used to obtain Young's, bulk, shear moduli and Poisson's ratio directly. We also calculated elastic constants using formulae of linear elasticity and analyzed the results obtained by direct deformation and interconversion methods. The elastic properties determined from these two approaches are in good agreement with each other and also with experimental data.

  9. Specific absorption rate calculations of magnetite, using a modified linear response model for applications in magnetic hyperthermia

    Energy Technology Data Exchange (ETDEWEB)

    Hernández S, A., E-mail: h.s.alfonso@gmail.com, E-mail: meduardo2001@hotmail.com; Cano, M. E., E-mail: h.s.alfonso@gmail.com, E-mail: meduardo2001@hotmail.com [Centro Universitario de la Ciénega, Universidad de Guadalajara, Ocotlán, Jalisco (Mexico); Torres-Arenas, J., E-mail: torresare@gmail.com [Division de Ciencias e Ingenierías, Universidad de Guanajuato, León, Guanajuato (Mexico)

    2014-11-07

    Currently the absorption of electromagnetic radiation by magnetic nanoparticles is studied for biomedical applications of cancer thermotherapy. Several experiments are conduced following the framework of the Rosensweig model, in order to estimate their specific absorption rate. Nevertheless, this linear approximation involves strong simplifications which constrain their accuracy and validity range. The main aim of this work is to incorporate the deviation of the sphericity assumption in particles shapes, to improve the determination of their specific absorption rate. The correction to the effective particles volume is computed as a measure of the apparent amount of magnetic material, interacting with the external AC magnetic field. Preliminary results using the physical properties of Fe3O4 nanoparticles, exhibit an important correction in their estimated specific absorption rate, as a function of the apparent mean particles radius. Indeed, we have observed using a small deviation (6% of the apparent radius), up to 40% of the predicted specific absorption rate by the Rosensweig linear approximation.

  10. Impact of turbulence on the prediction of linear aeroacoustic interactions: Acoustic response of a turbulent shear layer

    Science.gov (United States)

    Gikadi, Jannis; Föller, Stephan; Sattelmayer, Thomas

    2014-12-01

    A powerful model to predict aeroacoustic interactions in the linear regime is the perturbed compressible linearized Navier-Stokes equations. Thus far, the frequently employed derivation suggests that the effect of turbulence and its associated Reynolds stresses is neglected and a quasi-laminar model is employed. In this paper, dynamic perturbation equations are derived incorporating the effect of turbulence and its interaction with perturbation quantities. This is done by employing a triple decomposition of the instantaneous variables. The procedure results in a closure problem for the Reynolds stresses for which a linear eddy-viscosity model is proposed. The resulting perturbation equations are applied to a grazing flow in a T-joint for which strong shear layer instabilities at certain frequencies are experimentally observed. Passive scattering properties of the grazing flow are validated against the experiments performed by Karlsson and Åbom and perturbation equations being quasi-laminar. We find that prediction models must include the effect of Reynolds stresses to capture the aeroacoustic interaction effects correctly. Neglecting its effect naturally results in the over prediction of vortex growth at the frequencies of shear layer instability and therewith in an over prediction of aeroacoustic interactions.

  11. A chemo-electro-mechanical model for simulation of responsive deformation of glucose-sensitive hydrogels with the effect of enzyme catalysis

    Science.gov (United States)

    Li, Hua; Luo, Rongmo; Birgersson, Erik; Lam, Khin Yong

    2009-02-01

    A multi-effect-coupling glucose-stimulus (MECglu) model is developed and solved numerically for the swelling behavior of soft smart hydrogels responding to changes in the environmental glucose concentration. The model considers the effect of the glucose oxidation reaction catalyzed by enzymes including glucose oxidase and catalase. It is composed of the Nernst-Planck equation for the mobile species in the solvent, the Poisson equation for the electric potential, and a nonlinear mechanical equation for the large deformations of the hydrogel that arise due to the conversion of chemical energy to mechanical. Based on the theory of the chemo-electro-mechanical-coupled fields, the formulation of the fixed charge groups bound onto the cross-linked polymer network is associated with the change of the ambient solution pH. The MECglu model is validated by comparison between the steady-state computation and experimental equilibrium swelling curves, and good agreement is obtained. A parameter study is then conducted by steady-state simulations to ascertain the impact of various solvent parameters on the responsive swelling behavior of the hydrogel. One key parameter is the glucose concentration, which is varied within the range of practical physiological glucose concentrations from 0 to 16.5 mM (300 mg/ml) to support the design and optimization of an insulin delivery system based on a glucose-sensitive hydrogel with immobilized glucose oxidase and catalase. The influence of oxygen and glucose concentrations in the solvent is then further studied for the distributive profiles of reacting and diffusive species concentrations, the electric potential, the displacement, as well as the swelling ratio of the glucose-sensitive hydrogel.

  12. Vibrational absorption spectra from vibrational coupled cluster damped linear response functions calculated using an asymmetric Lanczos algorithm

    DEFF Research Database (Denmark)

    Thomsen, Bo; Hansen, Mikkel Bo; Seidler, Peter

    2012-01-01

    We report the theory and implementation of vibrational coupled cluster (VCC) damped response functions. From the imaginary part of the damped VCC response function the absorption as function of frequency can be obtained, requiring formally the solution of the now complex VCC response equations...... with results from the recently reported [P. Seidler, M. B. Hansen, W. Györffy, D. Toffoli, and O. Christiansen, J. Chem. Phys. 132, 164105 (2010)] vibrational configuration interaction damped response function calculated using a symmetric Lanczos algorithm. Calculations of IR spectra of oxazole, cyclopropene...

  13. Effect of -OH functionalization, C2 methylation, and high radiation fields on the non-linear optical response of imidazolium ionic liquids

    Science.gov (United States)

    Namboodiri, Vinu V.; Guleria, Apurav; Singh, Ajay K.

    2017-04-01

    Considering the impending applications of room temperature ionic liquids (RTILs) in various areas involving high optical and radiation fields, it is pertinent to probe the structure-property correlation of these solvents exposed to such conditions. Herein, femtosecond Z-scan technique (at high pulse repetition rate, 80 MHz) was employed to investigate the non-linear optical response of imidazolium RTILs in 3 scenarios: (1) -OH functionalization, (2) C2 methylation, and (3) influence of high radiation fields. Large negative non-linear refractive values ( n 2) were observed in all the RTIL samples and have been attributed predominantly due to the thermal effects. In order to isolate and determine the contribution of electronic Kerr effect, the Z-scan experiments were also carried out at low pulse repetition rate (i.e. 500 Hz) by means of a mechanical chopper. The closed aperture transmittance profile showed the valley-peak pattern, which signifies positive non-linearity. Nonetheless, the variation in the n2 values of the RTILs follows the same trend in low pulse repetition rate as was observed in case of high pulse repetition rate. The trend in the n 2 values clearly showed the decrease in the non-linearity in the first two cases and has been attributed to the weakening of the ion-pair formation, which adversely affects the charge transfer between the ionic moieties via C2 position. However, an increase in the n 2 values was observed in case of ILs irradiated to high radiation doses. This enhancement in the non-linearity has been assigned to the formation of double bond order radiolytic products. These results clearly indicate a strong correlation between the non-linearity and the strength of cation-anion interaction amongst them. Therefore, such information about these solvents may significantly contribute to the fundamental understanding of their structure-property relationships.

  14. Nonlinear flexural response of a slender cantilever beam of constant thickness and linearly-varying width to a primary resonance excitation

    Science.gov (United States)

    Silva, Clodoaldo J.; Daqaq, Mohammed F.

    2017-02-01

    Despite the shear amount of research studies on nonlinear flexural dynamics of cantilever beams, very few efforts address the practical geometry involving a constant thickness and linearly-varying width. This stems from the nature of the associated linear eigenvalue problem which cannot be easily solved in closed form. In this paper, we present a closed-form solution to this particular linear eigenvalue problem in the form of a general Meijer-G differential equation for which a solution is readily available in the shape of the Meijer-G functions. Using this approach, the exact linear modal frequencies and shapes are obtained and used in the discretization of the nonlinear partial-differential equation describing the dynamics of the system. The discretized system of ordinary-differential equations is then solved using the method of multiple scales to obtain an approximate analytical solution describing the primary resonance behavior of a given vibration mode. An analytical expression for the modal effective nonlinearity is obtained and used to analyze the influence of the beam's tapering on the nonlinear primary resonance behavior of the response (softening/hardening). Results are then compared to a finite element (FE) solution of the linear eigenvalue problem in which the modal shapes obtained using the FE method are fit into a set of orthogonal polynomial functions and used to discretize the nonlinear problem. It is shown that, while the modal frequencies obtained using the FE method approximate those obtained analytically with negligible error (less than 1%), there is a substantial error in the resulting estimates of the modal effective nonlinearity. This indicates that, even negligible errors in the approximate solution of the linear problem, can propagate to become significant when analyzing the nonlinear problem further reinforcing the importance of the exact solution.

  15. Towards a unifying theory for the first-, second-, and third-order molecular (non)linear optical response

    Science.gov (United States)

    Pérez-Moreno, Javier; Clays, Koen; Kuzyk, Mark G.

    2010-05-01

    We present a procedure for the modeling of the dispersion of the nonlinear optical response of complex molecular structures that is based strictly on the results from experimental characterization. We show how under some general conditions, the use of the Thomas-Kuhn sum-rules leads to a successful modeling of the nonlinear response of complex molecular structures.

  16. Non-linear neuronal responses as an emergent property of afferent networks: a case study of the locust lobula giant movement detector.

    Directory of Open Access Journals (Sweden)

    Sergi Bermúdez i Badia

    2010-03-01

    Full Text Available In principle it appears advantageous for single neurons to perform non-linear operations. Indeed it has been reported that some neurons show signatures of such operations in their electrophysiological response. A particular case in point is the Lobula Giant Movement Detector (LGMD neuron of the locust, which is reported to locally perform a functional multiplication. Given the wide ramifications of this suggestion with respect to our understanding of neuronal computations, it is essential that this interpretation of the LGMD as a local multiplication unit is thoroughly tested. Here we evaluate an alternative model that tests the hypothesis that the non-linear responses of the LGMD neuron emerge from the interactions of many neurons in the opto-motor processing structure of the locust. We show, by exposing our model to standard LGMD stimulation protocols, that the properties of the LGMD that were seen as a hallmark of local non-linear operations can be explained as emerging from the dynamics of the pre-synaptic network. Moreover, we demonstrate that these properties strongly depend on the details of the synaptic projections from the medulla to the LGMD. From these observations we deduce a number of testable predictions. To assess the real-time properties of our model we applied it to a high-speed robot. These robot results show that our model of the locust opto-motor system is able to reliably stabilize the movement trajectory of the robot and can robustly support collision avoidance. In addition, these behavioural experiments suggest that the emergent non-linear responses of the LGMD neuron enhance the system's collision detection acuity. We show how all reported properties of this neuron are consistently reproduced by this alternative model, and how they emerge from the overall opto-motor processing structure of the locust. Hence, our results propose an alternative view on neuronal computation that emphasizes the network properties as opposed

  17. Highly deformable nanofilaments in flow

    Science.gov (United States)

    Pawłowska, S.

    2016-10-01

    Experimental analysis of hydrogel nanofilaments conveyed by flow is conducted to help in understanding physical phenomena responsible for transport properties and shape deformations of long bio-objects, like DNA or proteins. Investigated hydrogel nanofilaments exhibit typical macromolecules-like behavior, as spontaneous conformational changes and cross-flow migration. Results of the experiments indicate critical role of thermal fluctuations behavior of single filaments.

  18. Optical tweezer for probing erythrocyte membrane deformability

    CERN Document Server

    Khan, Manas; Sood, A K; 10.1063/1.3272269

    2010-01-01

    We report that the average rotation speed of optically trapped crenated erythrocytes is direct signature of their membrane deformability. When placed in hypertonic buffer, discocytic erythrocytes are subjected to crenation. The deformation of cells brings in chirality and asymmetry in shape that make them rotate under the scattering force of a linearly polarized optical trap. A change in the deformability of the erythrocytes, due to any internal or environmental factor, affects the rotation speed of the trapped crenated cells. Here we show how the increment in erythrocyte membrane rigidity with adsorption of $Ca^{++}$ ions can be exhibited through this approach.

  19. An update on modeling dose-response relationships: Accounting for correlated data structure and heterogeneous error variance in linear and nonlinear mixed models.

    Science.gov (United States)

    Gonçalves, M A D; Bello, N M; Dritz, S S; Tokach, M D; DeRouchey, J M; Woodworth, J C; Goodband, R D

    2016-05-01

    Advanced methods for dose-response assessments are used to estimate the minimum concentrations of a nutrient that maximizes a given outcome of interest, thereby determining nutritional requirements for optimal performance. Contrary to standard modeling assumptions, experimental data often present a design structure that includes correlations between observations (i.e., blocking, nesting, etc.) as well as heterogeneity of error variances; either can mislead inference if disregarded. Our objective is to demonstrate practical implementation of linear and nonlinear mixed models for dose-response relationships accounting for correlated data structure and heterogeneous error variances. To illustrate, we modeled data from a randomized complete block design study to evaluate the standardized ileal digestible (SID) Trp:Lys ratio dose-response on G:F of nursery pigs. A base linear mixed model was fitted to explore the functional form of G:F relative to Trp:Lys ratios and assess model assumptions. Next, we fitted 3 competing dose-response mixed models to G:F, namely a quadratic polynomial (QP) model, a broken-line linear (BLL) ascending model, and a broken-line quadratic (BLQ) ascending model, all of which included heteroskedastic specifications, as dictated by the base model. The GLIMMIX procedure of SAS (version 9.4) was used to fit the base and QP models and the NLMIXED procedure was used to fit the BLL and BLQ models. We further illustrated the use of a grid search of initial parameter values to facilitate convergence and parameter estimation in nonlinear mixed models. Fit between competing dose-response models was compared using a maximum likelihood-based Bayesian information criterion (BIC). The QP, BLL, and BLQ models fitted on G:F of nursery pigs yielded BIC values of 353.7, 343.4, and 345.2, respectively, thus indicating a better fit of the BLL model. The BLL breakpoint estimate of the SID Trp:Lys ratio was 16.5% (95% confidence interval [16.1, 17.0]). Problems with

  20. Greater expectations: using hierarchical linear modeling to examine expectancy for treatment outcome as a predictor of treatment response.

    Science.gov (United States)

    Price, Matthew; Anderson, Page; Henrich, Christopher C; Rothbaum, Barbara Olasov

    2008-12-01

    A client's expectation that therapy will be beneficial has long been considered an important factor contributing to therapeutic outcomes, but recent empirical work examining this hypothesis has primarily yielded null findings. The present study examined the contribution of expectancies for treatment outcome to actual treatment outcome from the start of therapy through 12-month follow-up in a clinical sample of individuals (n=72) treated for fear of flying with either in vivo exposure or virtual reality exposure therapy. Using a piecewise hierarchical linear model, outcome expectancy predicted treatment gains made during therapy but not during follow-up. Compared to lower levels, higher expectations for treatment outcome yielded stronger rates of symptom reduction from the beginning to the end of treatment on 2 standardized self-report questionnaires on fear of flying. The analytic approach of the current study is one potential reason that findings contrast with prior literature. The advantages of using hierarchical linear modeling to assess interindividual differences in longitudinal data are discussed.

  1. Negative feedback regulation is responsible for the non-linear modulation of photosynthetic activity in plants and cyanobacteria exposed to a dynamic light environment.

    Science.gov (United States)

    Nedbal, Ladislav; Brezina, Vítezslav; Adamec, Frantisek; Stys, Dalibor; Oja, Vello; Laisk, Agu; Govindjee

    2003-10-17

    Photosynthetic organisms exposed to a dynamic light environment exhibit complex transients of photosynthetic activities that are strongly dependent on the temporal pattern of the incident irradiance. In a harmonically modulated light of intensity I approximately const.+sin(omegat), chlorophyll fluorescence response consists of a steady-state component, a component modulated with the angular frequency of the irradiance omega and several upper harmonic components (2omega, 3omega and higher). Our earlier reverse engineering analysis suggests that the non-linear response can be caused by a negative feedback regulation of photosynthesis. Here, we present experimental evidence that the negative feedback regulation of the energetic coupling between phycobilisome and Photosystem II (PSII) in the cyanobacterium Synechocystis sp. PCC6803 indeed results in the appearance of upper harmonic modes in the chlorophyll fluorescence emission. Dynamic changes in the coupling of the phycobilisome to PSII are not accompanied by corresponding antiparallel changes in the Photosystem I (PSI) excitation, suggesting a regulation limited to PSII. Strong upper harmonic modes were also found in the kinetics of the non-photochemical quenching (NPQ) of chlorophyll fluorescence, of the P700 redox state and of the CO(2) assimilation in tobacco (Nicotiana tabaccum) exposed to harmonically modulated light. They are ascribed to negative feedback regulation of the reactions of the Calvin-Benson cycle limiting the photosynthetic electron transport. We propose that the observed non-linear response of photosynthesis may also be relevant in a natural light environment that is modulated, e.g., by ocean waves, moving canopy or by varying cloud cover. Under controlled laboratory conditions, the non-linear photosynthetic response provides a new insight into dynamics of the regulatory processes.

  2. The linear response function of an idealized atmosphere: construction using Green's functions, applications, and implications for the practical use of the fluctuation-dissipation theorem

    CERN Document Server

    Hassanzadeh, Pedram

    2015-01-01

    A linear response function (LRF) determines the mean-response of a nonlinear climate system to weak imposed forcings, and an eddy flux matrix (EFM) determines the eddy momentum and heat flux responses to mean-flow changes. Neither LRF nor EFM can be calculated from first principles due the lack of a complete theory for turbulent eddies. Here the LRF and EFM for an idealized dry atmosphere are computed by applying numerous localized weak forcings, one at a time, to a GCM with Held-Suarez physics and calculating the mean-responses. The LRF and EFM for zonally-averaged responses are then constructed using these forcings and responses through matrix inversion. Tests demonstrate that LRF and EFM are fairly accurate. Spectral analysis of the LRF shows that the most excitable dynamical mode, the neutral vector, strongly resembles the model's Annular Mode. The framework described here can be employed to compute the LRF/EFM for zonally-asymmetric responses and more complex GCMs. The potential applications of the LRF/E...

  3. A flowing liquid test system for assessing the linearity and time-response of rapid fibre optic oxygen partial pressure sensors.

    Science.gov (United States)

    Chen, R; Hahn, C E W; Farmery, A D

    2012-08-15

    The development of a methodology for testing the time response, linearity and performance characteristics of ultra fast fibre optic oxygen sensors in the liquid phase is presented. Two standard medical paediatric oxygenators are arranged to provide two independent extracorporeal circuits. Flow from either circuit can be diverted over the sensor under test by means of a system of rapid cross-over solenoid valves exposing the sensor to an abrupt change in oxygen partial pressure, P O2. The system is also capable of testing the oxygen sensor responses to changes in temperature, carbon dioxide partial pressure P CO2 and pH in situ. Results are presented for a miniature fibre optic oxygen sensor constructed in-house with a response time ≈ 50 ms and a commercial fibre optic sensor (Ocean Optics Foxy), when tested in flowing saline and stored blood.

  4. Dynamic Measurements of Plastic Deformation in a Water-Filled Aluminum Tube in Response to Detonation of a Small Explosives Charge

    Directory of Open Access Journals (Sweden)

    Harold Sandusky

    1999-01-01

    Full Text Available Experiments have been conducted to benchmark computer code calculations for the dynamic interaction of explosions in water with structures. Aluminum cylinders with a length slightly more than twice their diameter were oriented vertically, sealed on the bottom by a thin plastic sheet, and filled with distilled water. An explosive charge suspended in the center of the tube plastically deformed but did not rupture the wall. Tube wall velocity, displacement, and strain were directly measured. The agreement among the three sets of dynamic data and the agreement of the terminal displacement measurements with the residual deformation were excellent.

  5. A shear deformable theory of laminated composite shallow shell-type panels and their response analysis. I - Free vibration and buckling

    Science.gov (United States)

    Librescu, L.; Khdeir, A. A.; Frederick, D.

    1989-01-01

    This paper deals with the substantiation of a shear deformable theory of cross-ply laminated composite shallow shells. While the developed theory preserves all the advantages of the first order transverse shear deformation theory it succeeds in eliminating some of its basic shortcomings. The theory is further employed in the analysis of the eigenvibration and static buckling problems of doubly curved shallow panels. In this context, the state space concept is used in conjunction with the Levy method, allowing one to analyze these problems in a unified manner, for a variety of boundary conditions. Numerical results are presented and some pertinent conclusions are formulated.

  6. Deformable mirror with thermal actuators.

    Science.gov (United States)

    Vdovin, Gleb; Loktev, Mikhail

    2002-05-01

    Low-cost adaptive optics is applied in lasers, scientific instrumentation, ultrafast sciences, and ophthalmology. These applications demand that the deformable mirrors used be simple, inexpensive, reliable, and efficient. We report a novel type of ultralow-cost deformable mirror with thermal actuators. The device has a response time of ~5 s , an actuator stroke of ~6mum , and temporal stability of ~lambda/10 rms in the visible range and can be used for correction of rather large aberrations with slow-changing amplitude.

  7. The Pedersen current carried by electrons: a non-linear response of the ionosphere to magnetospheric forcing

    Directory of Open Access Journals (Sweden)

    S. C. Buchert

    2008-09-01

    Full Text Available Observations by the EISCAT Svalbard radar show that electron temperatures Te in the cusp electrojet reach up to about 4000 K. The heat is tapped and converted from plasma convection in the near Earth space by a Pedersen current that is carried by electrons due to the presence of irregularities and their demagnetising effect. The heat is transfered to the neutral gas by collisions. In order to enhance Te to such high temperatures the maximally possible dissipation at 50% demagnetisation must nearly be reached. The effective Pedersen conductances are found to be enhanced by up to 60% compared to classical values. Conductivities and conductances respond significantly to variations of the electric field strength E, and "Ohm's law" for the ionosphere becomes non-linear for large E.

  8. Integrable deformations of T-dual $\\sigma$ models

    CERN Document Server

    Borsato, Riccardo

    2016-01-01

    We present a method to deform (generically non-abelian) T duals of two-dimensional $\\sigma$ models, which preserves classical integrability. The deformed models are identified by a linear operator $\\omega$ on the dualised subalgebra, which satisfies the 2-cocycle condition. We prove that the so-called homogeneous Yang-Baxter deformations are equivalent, via a field redefinition, to our deformed models when $\\omega$ is invertible. We explain the details for deformations of T duals of Principal Chiral Models, and present the corresponding generalisation to the case of supercoset models.

  9. Surface deformations and wave generation by wind blowing over a viscous liquid

    CERN Document Server

    Paquier, Anna; Rabaud, Marc

    2015-01-01

    We investigate experimentally the early stage of the generation of waves by a turbulent wind at the surface of a viscous liquid. The spatio-temporal structure of the surface deformation is analyzed by the optical method Free Surface Synthetic Schlieren, which allows for time-resolved measurements with a micrometric accuracy. Because of the high viscosity of the liquid, the flow induced by the turbulent wind in the liquid remains laminar, with weak surface drift velocity. Two regimes of deformation of the liquid-air interface are identified. In the first regime, at low wind speed, the surface is dominated by rapidly propagating disorganized wrinkles, elongated in the streamwise direction, which can be interpreted as the surface response to the pressure fluctuations advected by the turbulent airflow. The amplitude of these deformations increases approximately linearly with wind velocity and are essentially independent of the fetch (distance along the channel). Above a threshold in wind speed, the perturbations ...

  10. Deformations of crystal frameworks

    CERN Document Server

    Borcea, Ciprian S

    2011-01-01

    We apply our deformation theory of periodic bar-and-joint frameworks to tetrahedral crystal structures. The deformation space is investigated in detail for frameworks modelled on quartz, cristobalite and tridymite.

  11. Linear models with R

    CERN Document Server

    Faraway, Julian J

    2014-01-01

    A Hands-On Way to Learning Data AnalysisPart of the core of statistics, linear models are used to make predictions and explain the relationship between the response and the predictors. Understanding linear models is crucial to a broader competence in the practice of statistics. Linear Models with R, Second Edition explains how to use linear models in physical science, engineering, social science, and business applications. The book incorporates several improvements that reflect how the world of R has greatly expanded since the publication of the first edition.New to the Second EditionReorganiz

  12. Comparison of real-time and linear-response time-dependent density functional theories for molecular chromophores ranging from sparse to high densities of states

    Energy Technology Data Exchange (ETDEWEB)

    Tussupbayev, Samat; Govind, Niranjan; Lopata, Kenneth A.; Cramer, Christopher J.

    2015-03-10

    We assess the performance of real-time time-dependent density functional theory (RT-TDDFT) for the calculation of absorption spectra of 12 organic dye molecules relevant to photovoltaics and dye sensitized solar cells with 8 exchange-correlation functionals (3 traditional, 3 global hybrids, and 2 range-separated hybrids). We compare the calculations with traditional linear-response (LR) TDDFT. In addition, we demonstrate the efficacy of the RT-TDDFT approach to calculate wide absorption spectra of two large chromophores relevant to photovoltaics and molecular switches.

  13. Non-Linear Responses to Precipitation and Shrub Encroachment in Semi-Arid Grassland: Isotopes and CO2 Fluxes Reveal Soil Microsite Alteration as Explanation

    Science.gov (United States)

    Cable, J. M.; Sun, W.; Ogle, K.; Williams, D. G.; Potts, D. L.; Scott, R. L.; Huxman, T. E.

    2006-12-01

    Responses of net ecosystem production (NEP) to growing season rainfall amount is non-linear over a gradient of woody-plant encroachment in semi-arid riparian grassland. NEP is positively correlated with growing season precipitation amount in the grassland, but is negatively correlated with precipitation amount in a former C4 grassland now occupied by large mesquite (Prosopis) individuals. NEP at sites with intermediate stages of mesquite encroachment have a complex, threshold response to precipitation amount. Mesquite encroachment creates patchy soil microsites and spatial variation in rooting depth and activity. We hypothesized that variation in soil microsite properties (e.g., temperature, labile carbon) and root activity affect soil CO2 efflux in such a way that explains the non-linearity in response of NEP to precipitation. We measured soil CO2 efflux during the dry pre-monsoon (early summer) and wet monsoon (mid summer) periods on old floodplain terraces along the San Pedro River in southeastern Arizona. We made intensive spatial and temporal measurements of soil CO2 flux in four microsites associated with woody-plant encroachment: inter-canopy space and beneath the canopies of grasses, medium mesquite, and large mesquite. We also measured the δ13C of soil-respired CO2, which provided insight into the contribution of different sources (e.g., roots vs. microbes) to soil CO2 efflux. Soil respiration was highest beneath large mesquite near the canopy center, and lowest beneath medium mesquite and in inter-canopy spaces. The δ13C data revealed that soil respiration was dominated by a C4 signal during the pre-monsoon, but it switched to being dominated by the C3 mesquite signal during the wet monsoon period. Respiration was most sensitive to precipitation inputs beneath the large mesquite, where labile carbon in the form of mesquite litter is readily available. Conversely, soil respiration was least sensitive to precipitation in the open, inter- canopy space

  14. Impurity-related linear and nonlinear optical response in quantum-well wires with triangular cross section

    Energy Technology Data Exchange (ETDEWEB)

    Duque, C.A., E-mail: cduque@fisica.udea.edu.co [Instituto de Física, Universidad de Antioquia, AA 1226, Medellín (Colombia); Mora-Ramos, M.E. [Instituto de Física, Universidad de Antioquia, AA 1226, Medellín (Colombia); Facultad de Ciencias, Universidad Autónoma del Estado de Morelos, Ave. Universidad 1001, CP 62209, Cuernavaca, Morelos, México (Mexico); Kasapoglu, E.; Ungan, F.; Yesilgul, U. [Cumhuriyet University, Physics Department, 58140 Sivas (Turkey); Sakiroglu, S. [Dokuz Eylül University, Physics Department, 35160 Buca, İzmir (Turkey); Sari, H. [Cumhuriyet University, Physics Department, 58140 Sivas (Turkey); Sökmen, I. [Dokuz Eylül University, Physics Department, 35160 Buca, İzmir (Turkey)

    2013-11-15

    The 1s-like and 2p-like donor impurity energy states are studied in a semiconductor quantum wire of equilateral triangular cross section as functions of the impurity position and the geometrical size of the structure. Linear and nonlinear coefficients for the optical absorption and relative refractive index change associated with 1s→2p transitions are calculated for both the x-polarization and y-polarization of the incident light. The results show a mixed effect of redshift and blueshift depending on the location of the donor atom. Also, strong nonlinear contributions to the optical absorption coefficient are obtained for both polarizations in the on-center impurity case. -- Highlights: • The 1s- and 2p-like impurity states in triangular quantum-well wires. • Optical absorption and relative refractive index changes are calculated. • Redshift and blueshift in the optical structures depend on the donor position. • Strong nonlinear contributions to the absorption coefficient have been obtained.

  15. Response of Silicon-Based Linear Energy Transfer Spectrometers: Implication for Radiation Risk Assessment in Space Flights

    Science.gov (United States)

    Badhwar, G. D.; O'Neill, P. M.

    2001-01-01

    There is considerable interest in developing silicon-based telescopes because of their compactness and low power requirements. Three such telescopes have been flown on board the Space Shuttle to measure the linear energy transfer spectra of trapped, galactic cosmic ray, and solar energetic particles. Dosimeters based on single silicon detectors have also been flown on the Mir orbital station. A comparison of the absorbed dose and radiation quality factors calculated from these telescopes with that estimated from measurements made with a tissue equivalent proportional counter show differences which need to be fully understood if these telescopes are to be used for astronaut radiation risk assessments. Instrument performance is complicated by a variety of factors. A Monte Carlo-based technique was developed to model the behavior of both single element detectors in a proton beam, and the performance of a two-element, wide-angle telescope, in the trapped belt proton field inside the Space Shuttle. The technique is based on: (1) radiation transport intranuclear-evaporation model that takes into account the charge and angular distribution of target fragments, (2) Landau-Vavilov distribution of energy deposition allowing for electron escape, (3) true detector geometry of the telescope, (4) coincidence and discriminator settings, (5) spacecraft shielding geometry, and (6) the external space radiation environment, including albedo protons. The value of such detailed modeling and its implications in astronaut risk assessment is addressed. c2001 Elsevier Science B.V. All rights reserved.

  16. Molecular deformation mechanisms in polyethylene

    CERN Document Server

    Coutry, S

    2001-01-01

    adjacent labelled stems is significantly larger when the DPE guest is a copolymer molecule. Our comparative studies on various types of polyethylene lead to the conclusion that their deformation behaviour under drawing has the same basis, with additional effects imputed to the presence of tie-molecules and branches. Three major points were identified in this thesis. The changes produced by drawing imply (1) the crystallisation of some of the amorphous polymer and the subsequent orientation of the newly formed crystals, (2) the re-orientation of the crystalline ribbons and (3) the beginning of crystallite break-up. However, additional effects were observed for the high molecular weight linear sample and the copolymer sample and were attributed, respectively, to the presence of tie-molecules and of branches. It was concluded that both the tie-molecules and the branches are restricting the molecular movement during deformation, and that the branches may be acting as 'anchors'. This work is concerned with details...

  17. An On-Chip RBC Deformability Checker Significantly Improves Velocity-Deformation Correlation

    Directory of Open Access Journals (Sweden)

    Chia-Hung Dylan Tsai

    2016-10-01

    Full Text Available An on-chip deformability checker is proposed to improve the velocity–deformation correlation for red blood cell (RBC evaluation. RBC deformability has been found related to human diseases, and can be evaluated based on RBC velocity through a microfluidic constriction as in conventional approaches. The correlation between transit velocity and amount of deformation provides statistical information of RBC deformability. However, such correlations are usually only moderate, or even weak, in practical evaluations due to limited range of RBC deformation. To solve this issue, we implemented three constrictions of different width in the proposed checker, so that three different deformation regions can be applied to RBCs. By considering cell responses from the three regions as a whole, we practically extend the range of cell deformation in the evaluation, and could resolve the issue about the limited range of RBC deformation. RBCs from five volunteer subjects were tested using the proposed checker. The results show that the correlation between cell deformation and transit velocity is significantly improved by the proposed deformability checker. The absolute values of the correlation coefficients are increased from an average of 0.54 to 0.92. The effects of cell size, shape and orientation to the evaluation are discussed according to the experimental results. The proposed checker is expected to be useful for RBC evaluation in medical practices.

  18. Linear Systems.

    Science.gov (United States)

    The report documents a series of seminars at Rome Air Development Center with the content equivalent to an intense course in Linear Systems . Material...is slanted toward the practicing engineer and introduces some of the fundamental concepts and techniques for analyzing linear systems . Techniques for

  19. Chronic activation of plasma renin is log-linearly related to dietary sodium and eliminates natriuresis in response to a pulse change in total body sodium

    DEFF Research Database (Denmark)

    Kjolby, Mads; Bie, Peter

    2008-01-01

    data, we demonstrate that RAAS variables are log-linearly related to sodium intake over a >250-fold range in sodium intake, defining dietary sodium function lines that are simple measures of the sodium sensitivity of the RAAS. The dietary function line for plasma ANG II concentration increases from...... theoretical zero at a daily sodium intake of 17 mmol Na/kg (intercept) with a slope of 16 pM increase per decade of decrease in dietary sodium intake.......Responses to acute sodium loading depend on the load and on the level of chronic sodium intake. To test the hypothesis that an acute step increase in total body sodium (TBS) elicits a natriuretic response, which is dependent on the chronic level of TBS, we measured the effects of a bolus of Na...

  20. Linear Liquid Response of Morpho Butterfly Structural Color%Morpho 蝶翅结构色的线性液体反应

    Institute of Scientific and Technical Information of China (English)

    谢恒峰; 邬文俊

    2015-01-01

    The paper investigates the selective liquid response of Morpho butterfly wing scales.The ridge-lamellae structures on Morpho scales hold the secret of its famous blue structural color.The scales give different optical responses to different individual liquid media.Our optical model explains the effect of dif-ferent components on the liquid response.It is found that the selective response is attributed to the liquid media formed nanometre-thick films between scales lamellae and changed the constructive interference wavelength.It is discovered that there was linear relation between the structural color of ridge-lamellae structure and index of liquid background media.This linearity was verified through experiment,simulation and optic theory.This selective linear liquid response could be applied to design nano-engineered photonic sensors.%通过研究 Morpho 蝶翅鳞片的液体敏感性,发现蝶翅鳞片表面的三维微纳精细结构是其耀眼蓝色光泽的首要原因:蝶翅鳞片浸润在不同液体介质中,会发生不同的光学反应。通过光学模型解释了不同介质成分对液体反应的影响:发生这种选择性反应的原因是液体介质在鳞片层脊间形成了多层纳米薄膜,导致通过多层薄膜而发生相长干涉的波长发生了变化。研究发现蝶翅层脊结构的结构色和其液体氛围折射率之间存在线性关系,天然结构液体氛围实验的结果、几种仿蝶翅模型仿真结果与多层薄膜干涉理论完全匹配,验证了这一线性关系。这一选择性线性液体反应可以被用来设计纳米光子传感器。