WorldWideScience

Sample records for darpa grand challenge

  1. Virginia Tech team qualifies as DARPA Urban Challenge semi-finalist

    OpenAIRE

    Crumbley, Liz

    2007-01-01

    "VictorTango," a team of Virginia Tech engineering and geography students, will travel to Victorville, Calif., for the national qualifying rounds of the Urban Challenge autonomous vehicle competition, sponsored by the Defense Advanced Research Projects Agency (DARPA).

  2. Coordinated Exploration for Grand Challenges

    DEFF Research Database (Denmark)

    Ørding Olsen, Anders; Sofka, Wolfgang; Grimpe, Christoph

    2016-01-01

    Grand challenges are among the most complex problems for modern societies. Many governments and foundations provide substantial resources to encourage the search for solutions. Due to the significance of these problems, organizations often form partnerships in what we call search consortia to eng...

  3. A synopsis of the Defense Advanced Research Projects Agency (DARPA) investment in additive manufacture and what challenges remain

    Science.gov (United States)

    Maher, Michael; Smith, Adrien; Margiotta, Jesse

    2014-03-01

    DARPA's interest in additive manufacture dates back to the mid-80s with seedling programs that developed the foundational knowledge and equipment that led to the Solid Freeform Fabrication program in 1990. The drivers for this program included reducing development times by enabling "tool-less" manufacturing as well as integration of design and fabrication tools. DARPA consistently pushed the boundaries of additive manufacture with follow-on programs that expanded the material suite available for 3-D printing as well as new processes that expanded the technology's capability base. Programs such as the Mesoscopic Integrated Conformal Electronics (MICE) program incorporated functionality to the manufacturing processes through direct write of electronics. DARPA's investment in additive manufacture continues to this day but the focus has changed. DARPA's early investments were focused on developing and demonstrating the technology's capabilities. Now that the technology has been demonstrated, there is serious interest in taking advantage of the attributes unique to the processing methodology (such as customization and new design possibilities) for producing production parts. Accordingly, today's investment at DARPA addresses the systematic barriers to implementation rather than the technology itself. The Open Manufacturing program is enabling rapid qualification of new technologies for the manufacturing environment through the development of new modeling and informatics tools. While the technology is becoming more mainstream, there are plenty of challenges that need to be addressed. And as the technology continues to mature, the agency will continue to look for those "DARPA-hard" challenges that enable revolutionary changes in capability and performance for the Department of Defense.

  4. Grand Challenges of Enterprise Integration

    Energy Technology Data Exchange (ETDEWEB)

    Brosey, W.D; Neal, R.E.; Marks, D.

    2001-04-01

    Enterprise Integration connects and combines people, processes, systems, and technologies to ensure that the right people and the right processes have the right information and the right resources at the right time. A consensus roadmap for Technologies for Enterprise Integration was created as part of an industry/government/academia partnership in the Integrated Manufacturing Technology Initiative (IMTI). Two of the grand challenges identified by the roadmapping effort will be addressed here--Customer Responsive Enterprises and Totally Connected Enterprises. Each of these challenges is briefly discussed as to the current state of industry and the future vision as developed in the roadmap.

  5. Grand Challenges for Environmental Magnetism

    Science.gov (United States)

    Verosub, K. L.

    2009-05-01

    The development of new, inexpensive, and rapid geochemical methods for determining the ages of geologic materials, their elemental composition, and their isotopic ratios over a broad array of elements puts into sharp focus the question: What information can environmental magnetic methods provide that can't be obtained using these other methods? Because iron is ubiquitous in the Earth's crust and because it exists in so many different forms, a discipline that looks in detail at iron-bearing minerals does have the potential to make significant contributions to the study of surficial processes. However, to reach that potential requires the development of new environmental magnetic methods. I would like to put forward three Grand Challenges for environmental magnetism that have the potential to move the field forward to a new level of scientific sophistication and that will allow environmental magnetists to compete successfully in a world increasingly dominated by geochemists. The first Grand Challenge is the development of new techniques that lead to the direct and unambiguous identification of the full suite of magnetic minerals. For many environmental magnetic applications, the key magnetic minerals are not just magnetite and hematite but also iron oxy-hydroxides (goethite, lepidocrocite, akaganeite, ferrihydrite), carbonates (siderite) and sulfides (pyrrhotite and greigite) as well as compounds involving iron and other transition metals (cobalt and nickel). The second Grand Challenge is the development of new analytical methods that provide specific quantitative values for the amount of each magnetic mineral present in a sample. One promising approach to this problem is the application of two- or three-component multivariate analysis to arrays of downcore environmental magnetic parameters. The third Grand Challenge is the development of new ways of determining, not just the average values, but the actual distributions of grain sizes and coercivities of each mineral

  6. The Grand Challenges of Nanotechnology

    International Nuclear Information System (INIS)

    Lane, Neal

    2001-01-01

    Amazing breakthroughs and advances continue to be made in nanoscale science and engineering and the rapidly emerging field of nanotechnology, including near-commercial applications in biomedicine, computing and environmental protection. The National Nanotechnology Initiative, begun by the Clinton Administration has placed nanoscale research on a new funding trajectory. But, many 'grand challenges' must be overcome, technical ones as well as those related to funding, science and technology workforce, and the need for stronger collaboration across discipline, organizations, government agencies and with other countries

  7. Next Generation Innovation Policy and Grand Challenges

    NARCIS (Netherlands)

    Kuhlmann, Stefan; Rip, Arie

    2018-01-01

    The paper explores transformative ways to address Grand Challenges, while locating them in a broader diagnosis of ongoing changes. Coping with Grand Challenges is a challenge in its own right, for policy as well as for science, technology, and innovation actors. The paper presents building blocks

  8. IHMC's experience competing in the Cybathlon compared to the DARPA robotics challenge.

    Science.gov (United States)

    Neuhaus, Peter

    2017-11-09

    As a research scientist, my work tends to focus on scientific investigations. Our group occasionally makes discoveries or has a successful demonstration, and sometimes we can even repeatedly demonstrate something working on the hardware. This mode of operation works for research, but not for competitions. In the past few years, I have participated in two international robotics competitions, the DARPA Robotics Challenge (DRC) and the Cybathlon; the research and development process for these competitions is significantly different from our typical research work. This commentary discusses our experience preparing for the Cybathlon, and contrasts it with our experience with the DRC. The human in the loop for the Cybathlon was the biggest differentiator between the DRC and the Cybathlon. Having the human at the center of the competition not only changed the way we developed, but changed how we viewed the impact of our work. For the DRC, a physics based dynamic simulation was a powerful, and invaluable, tool for not only the algorithm developers, but the robot operator as well. For the Cybathlon, simulation was of little use because the all of closed-loop control was performed by the pilot. In the software development cycle for the Cybathlon, the push was to just come up with something that works and "lock it down" and do not change it, so that the pilot could train with a given set of motions that would not change and make up for any deficiencies with his own abilities. The Cybathlon was more of an athletic challenge for the human who was assisted by technology. The DRC was the opposite, it was a robotics challenge assisted by a human. This commentary focuses on describing the Florida Institute for Human and Machine Cognition's (IHMC) experience leading up to and at the Cybathlon, with some comparisons to the DRC experience. The Cybathlon was a very worthwhile experience me, my team, and of course our pilot. Knowing that our development could improve the quality of life

  9. 2010 Panel on the Biomaterials Grand Challenges

    Science.gov (United States)

    Reichert, William “Monty”; Ratner, Buddy D.; Anderson, James; Coury, Art; Hoffman, Allan S.; Laurencin, Cato T.; Tirrell, David

    2014-01-01

    In 2009, the National Academy for Engineering issued the Grand Challenges for Engineering in the 21st Century comprised of 14 technical challenges that must be addressed to build a healthy, profitable, sustainable, and secure global community (http://www.engineeringchallenges.org). Although crucial, none of the NEA Grand Challenges adequately addressed the challenges that face the biomaterials community. In response to the NAE Grand Challenges, Monty Reichert of Duke University organized a panel entitled Grand Challenges in Biomaterials at the at the 2010 Society for Biomaterials Annual Meeting in Seattle. Six members of the National Academies—Buddy Ratner, James Anderson, Allan Hoffman, Art Coury, Cato Laurencin, and David Tirrell—were asked to propose a grand challenge to the audience that, if met, would significantly impact the future of biomaterials and medical devices. Successfully meeting these challenges will speed the 60-plus year transition from commodity, off-the-shelf biomaterials to bioengineered chemistries, and biomaterial devices that will significantly advance our ability to address patient needs and also to create new market opportunities. PMID:21171147

  10. Grand Challenges facing Storage Systems

    CERN Multimedia

    CERN. Geneva

    2004-01-01

    In this talk, we will discuss the future of storage systems. In particular, we will focus on several big challenges which we are facing in storage, such as being able to build, manage and backup really massive storage systems, being able to find information of interest, being able to do long-term archival of data, and so on. We also present ideas and research being done to address these challenges, and provide a perspective on how we expect these challenges to be resolved as we go forward.

  11. Grand Challenges in Music Information Research

    OpenAIRE

    Goto, Masataka

    2012-01-01

    This paper discusses some grand challenges in which music information research will impact our daily lives and our society in the future. Here, some fundamental questions are how to provide the best music for each person, how to predict music trends, how to enrich human-music relationships, how to evolve new music, and how to address environmental, energy issues by using music technologies. Our goal is to increase both attractiveness and social impacts of music information research in the fut...

  12. Innovation at DARPA

    Science.gov (United States)

    2016-07-01

    Distribution Statement A: Approved for Public Release, Distribution Unlimited Innovation at DARPA July 2016 1 Distribution...Statement A: Approved for Public Release, Distribution Unlimited Innovation at DARPA A Long History of Innovation DARPA, the Defense Advanced Research...guided work that has “changed the world"—a phrase frequently heard at DARPA to ensure a focus on transformative innovation as opposed to incremental

  13. DARPA 7-Day Challenge

    Science.gov (United States)

    2014-03-17

    Thimma, J.; Kumuthaa, M.; Sekarana, S.; Vadivelua, J. In 13th International Congress on Infectious Diseases; Elsevier Ltd.: Kuala Lumpur, Malaysia , 2008...S. A.; Ventura, V. V.; Qazi, O.; Harding, S. V.; Kitto, G. B.; Estes, D. M.; Dell , A.; Titball, R. W.; Atkins, T. P.; Brown, K. A.; Hitchen, P. G

  14. Doing Business with DARPA

    Science.gov (United States)

    2009-03-01

    Approved For Public Release, Distribution Unlimited 1 Doing Business with DARPA Michael Blackstone Contracting Officer DARPA Contracts Management...DATE MAR 2009 2. REPORT TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE Doing Business with DARPA 5a. CONTRACT NUMBER...Topics: Business Process (Contracting Perspective) Pre-solicitation Solicitation Evaluation/Selection Negotiations Communications Approved For Public

  15. Workshop and conference on Grand Challenges applications and software technology

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-31

    On May 4--7, 1993, nine federal agencies sponsored a four-day meeting on Grand Challenge applications and software technology. The objective was to bring High-Performance Computing and Communications (HPCC) Grand Challenge applications research groups supported under the federal HPCC program together with HPCC software technologists to: discuss multidisciplinary computational science research issues and approaches, identify major technology challenges facing users and providers, and refine software technology requirements for Grand Challenge applications research. The first day and a half focused on applications. Presentations were given by speakers from universities, national laboratories, and government agencies actively involved in Grand Challenge research. Five areas of research were covered: environmental and earth sciences; computational physics; computational biology, chemistry, and materials sciences; computational fluid and plasma dynamics; and applications of artificial intelligence. The next day and a half was spent in working groups in which the applications researchers were joined by software technologists. Nine breakout sessions took place: I/0, Data, and File Systems; Parallel Programming Paradigms; Performance Characterization and Evaluation of Massively Parallel Processing Applications; Program Development Tools; Building Multidisciplinary Applications; Algorithm and Libraries I; Algorithms and Libraries II; Graphics and Visualization; and National HPCC Infrastructure.

  16. EV Everywhere Grand Challenge Road to Success

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-01-31

    Initial progress report for EV Everywhere. The report highlights the significant cost reduction in batteries in 2014, which will enable increased PEV affordability for consumers. Also, the efforts on increasing the convenience of PEVs through the Workplace Charging Challenge, which called on U.S. employers to help develop the nation's charging infrastructure.

  17. Grand societal challenges in information systems research and education

    CERN Document Server

    vom Brocke, Jan; Hofmann, Sara; Tumbas, Sanja

    2015-01-01

    This book examines how information systems research and education can play a major role in contributing to solutions to the Societal Grand Challenges formulated in "The Millennium Project" (millenium-project.org). Individual chapters focus on specific challenges, review existing approaches and contributions towards solutions in information systems research and outline a research agenda for these challenges. The topics considered in this volume range from climate change, population growth, global ICT availability, breakthroughs in science and technology and energy demand to ethical decision-making, policymaking, gender status and transnational crime prevention. It is the first book to present ideas on how the Information Systems discipline can contribute to the solution on this wide spectrum of grand societal challenges.

  18. Grand challenges for integrated USGS science—A workshop report

    Science.gov (United States)

    Jenni, Karen E.; Goldhaber, Martin B.; Betancourt, Julio L.; Baron, Jill S.; Bristol, R. Sky; Cantrill, Mary; Exter, Paul E.; Focazio, Michael J.; Haines, John W.; Hay, Lauren E.; Hsu, Leslie; Labson, Victor F.; Lafferty, Kevin D.; Ludwig, Kristin A.; Milly, Paul C. D.; Morelli, Toni L.; Morman, Suzette A.; Nassar, Nedal T.; Newman, Timothy R.; Ostroff, Andrea C.; Read, Jordan S.; Reed, Sasha C.; Shapiro, Carl D.; Smith, Richard A.; Sanford, Ward E.; Sohl, Terry L.; Stets, Edward G.; Terando, Adam J.; Tillitt, Donald E.; Tischler, Michael A.; Toccalino, Patricia L.; Wald, David J.; Waldrop, Mark P.; Wein, Anne; Weltzin, Jake F.; Zimmerman, Christian E.

    2017-06-30

    Executive SummaryThe U.S. Geological Survey (USGS) has a long history of advancing the traditional Earth science disciplines and identifying opportunities to integrate USGS science across disciplines to address complex societal problems. The USGS science strategy for 2007–2017 laid out key challenges in disciplinary and interdisciplinary arenas, culminating in a call for increased focus on a number of crosscutting science directions. Ten years on, to further the goal of integrated science and at the request of the Executive Leadership Team (ELT), a workshop with three dozen invited scientists spanning different disciplines and career stages in the Bureau convened on February 7–10, 2017, at the USGS John Wesley Powell Center for Analysis and Synthesis in Fort Collins, Colorado.The workshop focused on identifying “grand challenges” for integrated USGS science. Individual participants identified nearly 70 potential grand challenges before the workshop and through workshop discussions. After discussion, four overarching grand challenges emerged:Natural resource security,Societal risk from existing and emerging threats,Smart infrastructure development, andAnticipatory science for changing landscapes.Participants also identified a “comprehensive science challenge” that highlights the development of integrative science, data, models, and tools—all interacting in a modular framework—that can be used to address these and other future grand challenges:Earth Monitoring, Analyses, and Projections (EarthMAP)EarthMAP is our long-term vision for an integrated scientific framework that spans traditional scientific boundaries and disciplines, and integrates the full portfolio of USGS science: research, monitoring, assessment, analysis, and information delivery.The Department of Interior, and the Nation in general, have a vast array of information needs. The USGS meets these needs by having a broadly trained and agile scientific workforce. Encouraging and supporting

  19. US DOE Grand Challenge in Computational Accelerator Physics

    International Nuclear Information System (INIS)

    Ryne, R.; Habib, S.; Qiang, J.; Ko, K.; Li, Z.; McCandless, B.; Mi, W.; Ng, C.; Saparov, M.; Srinivas, V.; Sun, Y.; Zhan, X.; Decyk, V.; Golub, G.

    1998-01-01

    Particle accelerators are playing an increasingly important role in basic and applied science, and are enabling new accelerator-driven technologies. But the design of next-generation accelerators, such as linear colliders and high intensity linacs, will require a major advance in numerical modeling capability due to extremely stringent beam control and beam loss requirements, and the presence of highly complex three-dimensional accelerator components. To address this situation, the U.S. Department of Energy has approved a ''Grand Challenge'' in Computational Accelerator Physics, whose primary goal is to develop a parallel modeling capability that will enable high performance, large scale simulations for the design, optimization, and numerical validation of next-generation accelerators. In this paper we report on the status of the Grand Challenge

  20. The DARPA quantum network

    International Nuclear Information System (INIS)

    Elliot, B.

    2005-01-01

    Full text: The DARPA quantum network is now in initial operational, with six nodes performing quantum cryptography 24x7 across the Boston metro area between our campuses at Harvard University, Boston University, and BBN Technologies. In this talk, we present our recent activities, including the deployment of this network, building our Mark 1 Entangled QKD system, porting BBN QKD protocol software to NIST and Qinetiq freespace systems, performing initial design of a superconducting single photon detector with U. Rochester and NIST Boulder, and implementing a novel Low-Density Parity Check (LDPC) protocol for QKD. (author)

  1. Engineering grand challenges and the attributes of the global engineer

    DEFF Research Database (Denmark)

    Guerra, Aida; Ulseth, Ron; Jonhson, Bart

    2017-01-01

    Technology has been changing world in ways never imagined. The ever-evolving society and rapid development posed different demands and challenges to the engineering profession. Addressing these challenges means to re-vision and reform the ways we educate future engineers and the attributes need...... to be enhanced. This paper reports a literature review with aim to (1) understand the different stakeholders’ perspectives, namely students, educators, and employers, (2) understand the profile of the global engineer (i.e. knowledge, competences and skills), and (3) outline and discuss learning strategies....... As a result, the paper presents the main gaps in the existing knowledge, formulates research hypothesis, and proposes a research design for a follow up empirical study to investigate further the engineering grand challenges, the attributes needed to solve them, and the learning environments required....

  2. Is it possible to give scientific solutions to Grand Challenges? On the idea of grand challenges for life science research.

    Science.gov (United States)

    Efstathiou, Sophia

    2016-04-01

    This paper argues that challenges that are grand in scope such as "lifelong health and wellbeing", "climate action", or "food security" cannot be addressed through scientific research only. Indeed scientific research could inhibit addressing such challenges if scientific analysis constrains the multiple possible understandings of these challenges into already available scientific categories and concepts without translating between these and everyday concerns. This argument builds on work in philosophy of science and race to postulate a process through which non-scientific notions become part of science. My aim is to make this process available to scrutiny: what I call founding everyday ideas in science is both culturally and epistemologically conditioned. Founding transforms a common idea into one or more scientifically relevant ones, which can be articulated into descriptively thicker and evaluatively deflated terms and enable operationalisation and measurement. The risk of founding however is that it can invisibilise or exclude from realms of scientific scrutiny interpretations that are deemed irrelevant, uninteresting or nonsensical in the domain in question-but which may remain salient for addressing grand-in-scope challenges. The paper considers concepts of "wellbeing" in development economics versus in gerontology to illustrate this process. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Fostering Scientific Literacy: Establishing Social Relevance via the Grand Challenges

    Science.gov (United States)

    Lyford, M. E.; Myers, J. D.; Buss, A.

    2010-12-01

    Numerous studies and polls suggest the general public’s understanding of science and scientific literacy remain woefully inadequate despite repeated calls for improvement over the last 150 years. This inability to improve scientific literacy significantly is a complex problem likely driven by a number of factors. However, we argue that past calls and efforts for improving scientific literacy have failed to: 1) articulate a truly meaningful justification for society to foster a scientifically literate public; 2) provide a rationale that motivates individuals of diverse backgrounds to become scientifically literate; 3) consider the impact of personal perspective, e.g. values, beliefs, attitudes, etc., on learning; and 4) offer a relevant and manageable framework in which to define scientific literacy. For instance, past calls for improving scientific literacy, e.g. the U.S. is behind the Soviets in the space race, U.S students rank below country X in math and science, etc., have lacked justification, personal motivation and a comprehensive framework for defining scientific literacy. In these cases, the primary justification for improving science education and scientific literacy was to regain international dominance in the space race or to advance global standing according to test results. These types of calls also articulate short-term goals that are rendered moot once they have been achieved. At the same time, teaching practices have commonly failed to consider the perspectives students bring to the classroom. Many STEM faculty do not address issues of personal perspective through ignorance or the desire to avoid controversial subjects, e g. evolution, climate change. We propose that the ‘grand challenges’ (e.g., energy, climate change, antibacterial resistance, water, etc.) humankind currently faces provides a compelling framework for developing courses and curricula well-suited for improving scientific literacy. A grand challenge paradigm offers four

  4. Bringing Seismology's Grand Challenges to the Undergraduate Classroom

    Science.gov (United States)

    Benoit, M. H.; Taber, J.; Hubenthal, M.

    2011-12-01

    The "Seismological Grand Challenges in Understanding Earth's Dynamic Systems," a community-written long-range science plan for the next decade, poses 10 questions to guide fundamental seismological research. Written in an approachable fashion suitable for policymakers, the broad questions and supporting discussion contained in this document offer an ideal framework for the development of undergraduate curricular materials. Leveraging this document, we have created a collection of inquiry-based classroom modules that utilize authentic data to modernize seismological instruction in 100 and 200 level undergraduate courses. The modules not only introduce undergraduates to the broad questions that the seismological community seeks to answer in the future but also showcase the numerous areas where modern seismological research is actively contributing to our understanding of fundamental Earth processes. To date 6 in-depth explorations that correspond to the Grand Challenges document have been developed. The specific topics for each exploration were selected to showcase modern seismological research while also covering topics commonly included in the curriculum of these introductory classes. Examples of activities that have been created and their corresponding Grand Challenge include: -A guided inquiry that introduces students to episodic tremor and slip and compares the GPS and seismic signatures of ETS with those produced from standard tectonic earthquakes (Grand Challenge "How do faults slip?"). - A laboratory exercise where students engage in b-value mapping of volcanic earthquakes to assess potential eruption hazards (How do magmas ascend and erupt?). - A module that introduce students to glacial earthquakes in Greenland and compares their frequency and spatial distribution to tectonic earthquakes (How do processes in the ocean and atmosphere interact with the solid Earth?). What is the relationship between stress and strain in the lithosphere? - An activity that

  5. Grand Challenges in Clinical Decision Support v10

    Science.gov (United States)

    Sittig, Dean F.; Wright, Adam; Osheroff, Jerome A.; Middleton, Blackford; Teich, Jonathan M.; Ash, Joan S.; Campbell, Emily; Bates, David W.

    2008-01-01

    There is a pressing need for high-quality, effective means of designing, developing, presenting, implementing, evaluating, and maintaining all types of clinical decision support capabilities for clinicians, patients and consumers. Using an iterative, consensus-building process we identified a rank-ordered list of the top 10 grand challenges in clinical decision support. This list was created to educate and inspire researchers, developers, funders, and policy-makers. The list of challenges in order of importance that they be solved if patients and organizations are to begin realizing the fullest benefits possible of these systems consists of: Improve the human-computer interface; Disseminate best practices in CDS design, development, and implementation; Summarize patient-level information; Prioritize and filter recommendations to the user; Create an architecture for sharing executable CDS modules and services; Combine recommendations for patients with co-morbidities; Prioritize CDS content development and implementation; Create internet-accessible clinical decision support repositories; Use freetext information to drive clinical decision support; Mine large clinical databases to create new CDS. Identification of solutions to these challenges is critical if clinical decision support is to achieve its potential and improve the quality, safety and efficiency of healthcare. PMID:18029232

  6. First-Year Students' Attitudes towards the Grand Challenges and Nanotechnology

    Science.gov (United States)

    Lakin, Joni M.; Han, Yi; Davis, Edward

    2016-01-01

    The "Grand Challenges" for Engineering are an effort to portray engineering as a field that has profound impacts on society. This study explores the level of interest first-year engineering students had in various "Grand Challenges" and in nanotechnology topics. We administered a survey to a large sample of students enrolled in…

  7. On the Grand Challenges in Physical Petrology: the Multiphase Crossroads

    Science.gov (United States)

    Bergantz, G. W.

    2014-12-01

    Rapid progress in experimental, micro-analytical and textural analysis at the crystal scale has produced an unprecedented record of magmatic processes. However an obstacle to further progress is the lack of understanding of how mass, energy and momentum flux associated with crystal-rich, open-system events produces identifiable outcomes. Hence developing a physically-based understanding of magmatic systems linking micro-scale petrological observations with a physical template operating at the macro-scale presents a so-called "Grand Challenge." The essence of this challenge is that magmatic systems have characteristic length and feedback scales between those accessible by classical continuum and discrete methods. It has become increasingly obvious that the old-school continuum methods have limited resolution and power of explanation for multiphase (real) magma dynamics. This is, in part, because in crystal-rich systems the deformation is non-affine, and so the concept of constitutive behavior is less applicable and likely not even relevant, especially if one is interested in the emergent character of micro-scale processes. One expression of this is the cottage industry of proposing viscosity laws for magmas, which serves as "blunt force" de facto corrections for what is intrinsically multiphase behavior. Even in more fluid-rich systems many of these laws are not suitable for use in the very transport theories they aim to support. The alternative approach is the discrete method, where multiphase interactions are explicitly resolved. This is a daunting prospect given the numbers of crystals in magmas. But perhaps all crystals don't need to be modeled. I will demonstrate how discrete methods can recover critical state behavior, resolve crystal migration, the onset of visco-elastic behavior such as melt-present shear bands which sets the large-scale mixing volumes, some of the general morpho-dynamics that underlies purported rheological models, and transient controls on

  8. Analysis of the mass media coverage of the Gates Foundation grand challenges in global health initiative.

    Science.gov (United States)

    Verma, G

    2009-03-01

    The Grand Challenges were launched in 2003 by the Gates Foundation and other collaborators to address the health needs of developing countries. This paper outlines the current problem with health research and development in the context of inequality as conveyed by the 90/10 divide. The paper then looks at the focus and nature of press reporting of global health issues by analysing how press articles have portrayed the Grand Challenges in Global Health initiative. Analysis of the mass media illustrates that the focus of reporting on the Grand Challenges tends to be on utilitarian themes, leaving issues related to justice and equity comparatively under-reported.

  9. Grand challenge problems in environmental modeling and remediation: Groundwater contaminant transport. Final project report 1998

    International Nuclear Information System (INIS)

    1998-04-01

    The over-reaching goal of the Groundwater Grand Challenge component of the Partnership in Computational Science (PICS) was to develop and establish the massively parallel approach for the description of groundwater flow and transport and to address the problem of uncertainties in the data and its interpretation. This necessitated the development of innovative algorithms and the implementation of massively parallel computational tools to provide a suite of simulators for groundwater flow and transport in heterogeneous media. This report summarizes the activities and deliverables of the Groundwater Grand Challenge project funded through the High Performance Computing grand challenge program of the Department of Energy from 1995 through 1997

  10. A BLUEPRINT FOR IMPLEMENTING GRAND CHALLENGE SCHOLARS’ PROGRAMME: A CASE STUDY OF TAYLOR’S UNIVERSITY

    Directory of Open Access Journals (Sweden)

    MUSHTAK AL-ATABI

    2013-04-01

    Full Text Available The National Academy for Engineering announced 14 Grand Challenges for the 21st Century engineers to address in order to ensure a sustainable future for the generations to come. These grand challenges are in four broad areas, namely, energy and environment, health, security and learning and computation. This paper reports on a Grand Challenges Scholars’ Programme that is developed to prepare the engineering students to be able to address the grand challenges using the CDIO framework and focusing on five components; research experience, interdisciplinary curriculum, entrepreneurship, global dimension and service learning. The programme is voluntary and the candidates are expected to commit additional learning time. The programme was launched with 16 participants who are expected to graduate in 2016. A preliminary assessment of the programs shows that the participants found the programme useful in developing an array of CDIO skills. The School intends to continue offering this programme with the intention of integrating it with a holistic education approach.

  11. Grand challenges in technology enhanced learning outcomes of the 3rd Alpine Rendez-Vous

    CERN Document Server

    Fischer, Frank; Sutherland, Rosamund; Zirn, Lena

    2014-01-01

    This book presents a key piece of the vision and strategy developed in STELLAR. It sets out a new mid-term agenda by defining Grand Challenges for research and development in technology-enhanced learning. Other than mere technology prizes, STELLAR Grand Challenges deal with problems at the interface of social and technical sciences. They pose problems that can be solved only in interdisciplinary collaboration. The descriptions of the Grand Challenge Problems were sent out to a number of stakeholders from industry, academia, and policy-making who responded with insightful, creative and critical comments bringing in their specific perspectives. This book will inspire everyone interested in TEL and its neighboring disciplines in their future projects. All of the listed problems, first hints with respect to the approach, measurable success indicators and funding sources are outlined. The challenges focus on what noted experts regard as important upcoming, pending, and innovative fields of research, the solution o...

  12. Grand Challenges and Great Potential in Foreign Language Teaching and Learning

    Science.gov (United States)

    Hlas, Anne Cummings

    2018-01-01

    This article argues for the field of foreign languages to begin to identify and define our Grand Challenges, which are difficult yet solvable problems facing our field. Seeking answers to these challenges can provide new opportunities for collaboration and can spur new directions and innovation within language learning and teaching. Researchable…

  13. A Library in the Grands Moulins de Paris: challenging Reality

    Directory of Open Access Journals (Sweden)

    Catherine Tresson

    2006-07-01

    Full Text Available In 2006, the University of Paris 7 and its new Main Library will move to Paris Rive Gauche, a recently developed neighbourhood on the left bank of the Seine. The library will occupy most of the city’s former industrial mills, the Grands Moulins de Paris. As part of the project, the library developed a very detailed functional program. The facilities are expected to comprise 1,800 workstations (half of which will be computerized, and upon completion will have a capacity of 300,000 freely accessible documents and 350,000 documents in store over a total surface area of some 12,000 m2. The architect Rudy Ricciotti won the international competition to design the library held in 2001. Perfectly suited to its function, the industrial building in which the library is housed dates from the 1920s. It presents both advantages (vast surfaces, sufficient load-bearing capacity, natural light, etc. and obstacles (restrictions on free circulation, forests of columns in certain areas, interrupted spaces, etc. to being transformed into a library that is functional and adapted to its purposes. The building’s structure and the constraints it imposed profoundly influenced the program which had to be adjusted, and also affected other aspects, including the arrangement and features of the furnishings as well as the building’s system of signs. In agreement with the university, the library worked in close collaboration with the architect from the earliest sketches onwards. As a result, his initial plan also evolved considerably. The installation of the library in the Grands Moulins offers us a chance to observe the nature and effects of the interactions between the transformation of a building and the evolution of a program.

  14. Grand challenge commentary: Transforming biosynthesis into an information science.

    Science.gov (United States)

    Bayer, Travis S

    2010-12-01

    Engineering biosynthetic pathways to natural products is a challenging endeavor that promises to provide new therapeutics and tools to manipulate biology. Information-guided design strategies and tools could unlock the creativity of a wide spectrum of scientists and engineers by decoupling expertise from implementation.

  15. DARPA-funded efforts in the development of novel brain-computer interface technologies.

    Science.gov (United States)

    Miranda, Robbin A; Casebeer, William D; Hein, Amy M; Judy, Jack W; Krotkov, Eric P; Laabs, Tracy L; Manzo, Justin E; Pankratz, Kent G; Pratt, Gill A; Sanchez, Justin C; Weber, Douglas J; Wheeler, Tracey L; Ling, Geoffrey S F

    2015-04-15

    The Defense Advanced Research Projects Agency (DARPA) has funded innovative scientific research and technology developments in the field of brain-computer interfaces (BCI) since the 1970s. This review highlights some of DARPA's major advances in the field of BCI, particularly those made in recent years. Two broad categories of DARPA programs are presented with respect to the ultimate goals of supporting the nation's warfighters: (1) BCI efforts aimed at restoring neural and/or behavioral function, and (2) BCI efforts aimed at improving human training and performance. The programs discussed are synergistic and complementary to one another, and, moreover, promote interdisciplinary collaborations among researchers, engineers, and clinicians. Finally, this review includes a summary of some of the remaining challenges for the field of BCI, as well as the goals of new DARPA efforts in this domain. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  16. Grand Challenges and Chemical Engineering Curriculum--Developments at TU Dortmund University

    Science.gov (United States)

    Kockmann, Norbert; Lutze, Philip; Gorak, Andrzej

    2016-01-01

    Chemical processing industry is progressively focusing their research activities and product placements in the areas of Grand Challenges (or Global Megatrends) such as mobility, energy, communication, or health care and food. Innovation in all these fields requires solving high complex problems, rapid product development as well as dealing with…

  17. Promoting Collaborative Problem-Solving Skills in a Course on Engineering Grand Challenges

    Science.gov (United States)

    Zou, Tracy X. P.; Mickleborough, Neil C.

    2015-01-01

    The ability to solve problems with people of diverse backgrounds is essential for engineering graduates. A course on engineering grand challenges was designed to promote collaborative problem-solving (CPS) skills. One unique component is that students need to work both within their own team and collaborate with the other team to tackle engineering…

  18. Megatrends and grand challenges of cybercrime and cyberterrorism policy and research

    NARCIS (Netherlands)

    Koops, Bert Jaap; Akhgar, Babak; Brewster, Ben

    2016-01-01

    What are grand challenges of cybercrime and cyberterrorism policy and research for the coming one or two decades? To answer this question, we first need to grasp some major trends that influence the future of cybercrime and cyberterrorism, and the combatting thereof, in fundamental ways. This

  19. Management as a science-based profession: a grand societal challenge

    NARCIS (Netherlands)

    Romme, A.G.L.

    2017-01-01

    The purpose of this paper is to explore how the quest for management as a science-based profession, conceived as a grand societal challenge, can be revitalized. A reflective approach is adopted by questioning some of the key assumptions made by management scholars, especially those that undermine

  20. 75 FR 5634 - Grand Challenges of the 21st Century; Request for Information

    Science.gov (United States)

    2010-02-03

    ... careers in science, technology, engineering, and mathematics. There are multiple types of grand challenges. Some define important problems in a particular field of science and engineering. For example, in 1900... as those identified by the National Academy of Engineering; (3) partners (e.g., companies, investors...

  1. Grand challenge problems in environmental modeling and remediation: groundwater contaminant transport

    Energy Technology Data Exchange (ETDEWEB)

    Todd Arbogast; Steve Bryant; Clint N. Dawson; Mary F. Wheeler

    1998-08-31

    This report describes briefly the work of the Center for Subsurface Modeling (CSM) of the University of Texas at Austin (and Rice University prior to September 1995) on the Partnership in Computational Sciences Consortium (PICS) project entitled Grand Challenge Problems in Environmental Modeling and Remediation: Groundwater Contaminant Transport.

  2. Biological approaches for addressing the grand challenge of providing access to clean drinking water

    Science.gov (United States)

    2011-01-01

    The U.S. National Academy of Engineering (NAE) recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF). Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of providing access to clean drinking water. This issue must be addressed in part by removing or inactivating microbial and chemical contaminants in order to properly deliver water safe for human consumption. Despite many advances in technologies this challenge is expanding due to increased pressure on fresh water supplies and to new opportunities for growth of potentially pathogenic organisms. PMID:21453515

  3. Using Grand Challenges to Teach Science: A Biology-Geology Collaboration

    Science.gov (United States)

    Lyford, M.; Myers, J. D.

    2012-12-01

    Three science courses at the University of Wyoming explore the inextricable connections between science and society by centering on grand challenges. Two of these courses are introductory integrated science courses for non-majors while the third is an upper level course for majors and non-majors. Through collaboration, the authors have developed these courses to explore the grand challenges of energy, water and climate. Each course focuses on the fundamental STEM principles required for a citizen to understand each grand challenge. However, the courses also emphasize the non-STEM perspectives (e.g., economics, politics, human well-being, externalities) that underlie each grand challenge and argue that creating equitable, sustainable and just solutions to the grand challenges hinges on an understanding of STEM and non-STEM perspectives. Moreover, the authors also consider the multitude of personal perspectives individuals bring to the classroom (e.g., values, beliefs, empathy misconceptions) that influence any stakeholder's ability to engage in fruitful discussions about grand challenge solutions. Discovering Science (LIFE 1002) focuses on the grand challenges of energy and climate. Students attend three one-hour lectures, one two-hour lab and a one-hour discussion each week. Lectures emphasize the STEM and non-STEM principles underlying each grand challenge. Laboratory activities are designed to be interdisciplinary and engage students in inquiry-driven activities to reinforce concepts from lecture and to model how science is conducted. Labs also expose students to the difficulties often associated with scientific studies, the limits of science, and the inherent uncertainties associated with scientific findings. Discussion sessions provide an opportunity for students to explore the complexity of the grand challenges from STEM and non-STEM perspectives, and expose the multitude of personal perspectives an individual might harbor related to each grand challenge

  4. A Grand Challenge for CMOS Scaling: Alternate Gate Dielectrics

    Science.gov (United States)

    Wallace, Robert M.

    2001-03-01

    Many materials systems are currently under consideration as potential replacements for SiO2 as the gate dielectric material for sub-0.13 um complementary metal oxide semiconductor (CMOS) technology. The prospect of replacing SiO2 is a formidable task because the alternate gate dielectric must provide many properties that are, at a minimum, comparable to those of SiO2 yet with a much higher permittivity. A systematic examination of the required performance of gate dielectrics suggests that the key properties to consider in the selection an alternative gate dielectric candidate are (a) permittivity, band gap and band alignment to silicon, (b) thermodynamic stability, (c) film morphology, (d) interface quality, (e) compatibility with the current or expected materials to be used in processing for CMOS devices, (f) process compatibility, and (g) reliability. Many dielectrics appear favorable in some of these areas, but very few materials are promising with respect to all of these guidelines. We will review the performance requirements for materials associated with CMOS scaling, the challenges associated with these requirements, and the state-of-the-art in current research for alternate gate dielectrics. The requirements for process integration compatibility are remarkably demanding, and any serious candidates will emerge only through continued, intensive investigation.

  5. Building a Course on Global Sustainability using the grand challenges of Energy-Water-Climate

    Science.gov (United States)

    Myers, J. D.

    2012-12-01

    GEOL1600: Global Sustainability: Managing the Earth's Resources is a lower division integrated science course at the University of Wyoming that fulfills the university's science requirement. Course content and context has been developed using the grand challenge nexus of energy-water-and climate (EWC). The interconnection of these issues, their social relevance and timeliness has provided a framework that gives students an opportunity to recognize why STEM is relevant to their lives regardless of their ultimate professional career choices. The EWC nexus provides the filter to sieve the course's STEM content. It also provides an ideal mechanism by which the non-STEM perspectives important in grand challenge solutions can be seamlessly incorporated in the course. Through a combination of content and context, the relevance of these issues engage students in their own learning. Development of the course followed the Grand Challenge Scientific Literacy (GCSL) model independently developed by the author and two colleagues at the University of Wyoming. This course model stresses science principles centered on the nature of science (e.g., fundamental premises, habits of mind, critical thinking) and unifying scientific concepts (e.g., methods and tools, experimentation, modeling). Grand challenge principles identify the STEM and non-STEM concepts needed to understand the grand challenges, drawing on multiple STEM and non-STEM disciplines and subjects (i.e., economics, politics, unintended consequences, roles of stakeholders). Using the EWC nexus filter and building on the Grand Challenge Principles, specific content included in the course is selected is that most relevant to understanding the Grand Challenges, thereby stressing content depth over breadth. Because quantitative data and reasoning is critical to effectively evaluating challenge solutions, QR is a component of nearly all class activities, while engineering and technology aspects of grand challenges are

  6. The grand challenge of managing the petascale facility.

    Energy Technology Data Exchange (ETDEWEB)

    Aiken, R. J.; Mathematics and Computer Science

    2007-02-28

    This report is the result of a study of networks and how they may need to evolve to support petascale leadership computing and science. As Dr. Ray Orbach, director of the Department of Energy's Office of Science, says in the spring 2006 issue of SciDAC Review, 'One remarkable example of growth in unexpected directions has been in high-end computation'. In the same article Dr. Michael Strayer states, 'Moore's law suggests that before the end of the next cycle of SciDAC, we shall see petaflop computers'. Given the Office of Science's strong leadership and support for petascale computing and facilities, we should expect to see petaflop computers in operation in support of science before the end of the decade, and DOE/SC Advanced Scientific Computing Research programs are focused on making this a reality. This study took its lead from this strong focus on petascale computing and the networks required to support such facilities, but it grew to include almost all aspects of the DOE/SC petascale computational and experimental science facilities, all of which will face daunting challenges in managing and analyzing the voluminous amounts of data expected. In addition, trends indicate the increased coupling of unique experimental facilities with computational facilities, along with the integration of multidisciplinary datasets and high-end computing with data-intensive computing; and we can expect these trends to continue at the petascale level and beyond. Coupled with recent technology trends, they clearly indicate the need for including capability petascale storage, networks, and experiments, as well as collaboration tools and programming environments, as integral components of the Office of Science's petascale capability metafacility. The objective of this report is to recommend a new cross-cutting program to support the management of petascale science and infrastructure. The appendices of the report document current and projected

  7. The Grand Challenges Discourse: Transforming Identity Work in Science and Science Policy.

    Science.gov (United States)

    Kaldewey, David

    2018-01-01

    This article analyzes the concept of "grand challenges" as part of a shift in how scientists and policymakers frame and communicate their respective agendas. The history of the grand challenges discourse helps to understand how identity work in science and science policy has been transformed in recent decades. Furthermore, the question is raised whether this discourse is only an indicator, or also a factor in this transformation. Building on conceptual history and historical semantics, the two parts of the article reconstruct two discursive shifts. First, the observation that in scientific communication references to "problems" are increasingly substituted by references to "challenges" indicates a broader cultural trend of how attitudes towards what is problematic have shifted in the last decades. Second, as the grand challenges discourse is rooted in the sphere of sports and competition, it introduces a specific new set of societal values and practices into the spheres of science and technology. The article concludes that this process can be characterized as the sportification of science, which contributes to self-mobilization and, ultimately, to self-optimization of the participating scientists, engineers, and policymakers.

  8. A Grand Challenge: Immortal Information and Through-Life Knowledge Management (KIM

    Directory of Open Access Journals (Sweden)

    Alexander Ball

    2006-11-01

    Full Text Available ‘Immortal information and through-life knowledge management: strategies and tools for the emerging product-service business paradigm’, is a Grand Challenge project involving eleven different UK universities and incorporating substantial industry collaboration. It is investigating a range of issues associated with the move towards a product-service paradigm in the engineering sector, in particular the long-term curation of digital data, learning from production and use, and appropriate governance and management techniques.

  9. The Grand Canyon of the Colorado: a challenge to float, a challenge to manage

    Science.gov (United States)

    David N. Cole

    1989-01-01

    Last summer, I finally got my chance to float the Colorado River through the Grand Canyon, one of the world’s premier adventure trips. For 18 days and 280 miles, my group floated through some of the most spectacular scenery imaginable, spacing our days with hikes through slickrock alcoves, along terraced pools of blue-green water, to waterfalls plunging out of holes on...

  10. Grand Challenges Canada: inappropriate emphasis and missed opportunities in global health research?

    Science.gov (United States)

    Larson, Charles P; Haddad, Slim; Birn, Anne-Emanuelle; Cole, Donald C; Labonte, Ronald; Roberts, Janet Hatcher; Schrecker, Ted; Sellen, Daniel; Zakus, David

    2011-01-01

    In May 2010, Grand Challenges Canada (GCC) was launched with the mandate to identify global challenges in health that could be supported through the Government of Canada's Development Innovations Fund (DIF: $225 million over five years). The GCC offers a potentially excellent mechanism for taking Canada's participation in global health challenges "to a higher level". Recent GCC announcements raise new questions about the emphasis being placed on technological discovery or "catalytic" research. Missing so far are opportunities that the Fund could offer in order to support innovative research addressing i) health systems strengthening, ii) more effective delivery of existing interventions, and iii) policies and programs that address broader social determinants of health. The Canadian Grand Challenges announced to date risk pushing to the sidelines good translational and implementation science and early career-stage scientists addressing important social, environmental and political conditions that affect disease prevalence, progress and treatment; and the many unresolved challenges faced in bringing to scale proven interventions within resource-constrained health systems. We wish to register our concern at the apparent prioritization of biotechnical innovation research and the subordination of the social, environmental, economic and political context in which human health is either protected or eroded.

  11. A different challenge: the directional drilled crossing for the Yacuiba - Rio Grande Gas Line Project - GASYRG

    Energy Technology Data Exchange (ETDEWEB)

    Green, Wayne; Garcia, Francisco [Bolinter Ltda., Santa Cruz (Bolivia); Montano, Ruben [Transierra, Santa Cruz (Bolivia)

    2003-07-01

    The Rio Grande River's directional drilling, 2002 m. long and 25 m. deep was a great challenge for Transierra - Owner - as well as Laney - Bolinter - Contractor - to accomplish a feat yet to be done in the entire world. The dedication of the people involved showed their degree of professionalism that these companies have obtained and the determination in doing the job overcoming unforeseen obstacles and still being able to finish on time, mitigating environmental impacts and leaving a first class crossing. This document presents a description of the technical, logistic and construction factors that were involved in the project and which allowed to perform 7 directional drillings, including Rio Grande River, which during the pull got the last 60 m. of pipe stuck, being freed only after using a pneumatic hammer. (author)

  12. The New Global Governance Architectures on Grand Challenges and State Capacity

    DEFF Research Database (Denmark)

    Borrás, Susana

    . Aiming to address some specifically identified grand challenges the new governance architectures are creating broader and sustained conditions for problemsolving. But the extent to which they are able to generate the expected transformative change at the domestic level is an empirical question...... that remains open. This paper provides a framework for analyzing that by focusing on three main mediating factors at the domestic level, namely, the knowledge absorptive capacity of domestic actors, their organizational capacity, and their legitimacy as the communicative capacity with which they articulate...

  13. Proposed Grand Challenges in Geoscience Education Research: Articulating a Community Research Agenda

    Science.gov (United States)

    Semken, S. C.; St John, K. K.; Teasdale, R.; Ryker, K.; Riggs, E. M.; Pyle, E. J.; Petcovic, H. L.; McNeal, K.; McDaris, J. R.; Macdonald, H.; Kastens, K.; Cervato, C.

    2017-12-01

    Fourteen ago the Wingspread Project helped establish geoscience education research (GER) as an important research field and highlighted major research questions for GER at the time. More recently, the growth and interest in GER is evident from the increase in geoscience education research articles, the establishment of the NAGT GER Division, the creation of the GER Toolbox, an increase in GER graduate programs, and the growth of tenure-eligible GER faculty positions. As an emerging STEM education research field, the GER community is examining the current state of their research and considering the best course forward so that it can have the greatest collective impact on advancing teaching and learning in the geosciences. As part of an NSF-funded effort to meet this need, 45 researchers drafted priority research questions, or "Grand Challenges", that span 10 geoscience education research themes. These include research on: students' conceptual understanding of the solid and the fluid Earth, K-12 teacher preparation, teaching about Earth in the context of societal problems, access and success of underrepresented groups in the geosciences, spatial and temporal reasoning, quantitative reasoning and use of models, instructional strategies to improve geoscience learning, students' self-regulated learning, and faculty professional development and institutional change. For each theme, several Grand Challenges have been proposed; these have undergone one round of peer-review and are now ready for the AGU community to critically examine the proposed Grand Challenges and make suggestions on strategies for addressing them: http://nagt.org/nagt/geoedresearch/grand_challenges/feedback.html. We seek perspectives from geoscience education researchers, scholars, and reflective educators. It is our vision that the final outcomes of this community-grounded process will be a published guiding framework to (1) focus future GER on questions of high interest to the geoscience education

  14. Avoiding collapse: Grand challenges for science and society to solve by 2050

    Directory of Open Access Journals (Sweden)

    Anthony D. Barnosky

    2016-03-01

    Full Text Available Abstract We maintain that humanity’s grand challenge is solving the intertwined problems of human population growth and overconsumption, climate change, pollution, ecosystem destruction, disease spillovers, and extinction, in order to avoid environmental tipping points that would make human life more difficult and would irrevocably damage planetary life support systems. These are not future issues: for example, detrimental impacts of climate change (increased wildfires and extreme weather, sea-level rise, ocean acidification, pollution (contaminated drinking water in many parts of the world, rapid population growth in some areas (contributing to poverty, war, and increasingly frequent migration and overconsumption in others (a main driver of overexploitation of resources and greenhouse gas emissions, and new disease outbreaks (Ebola, Zika virus already are apparent today, and if trends of the past half century continue, even more damaging, long-lasting impacts would be locked in within three decades. Solving these problems will require some scientific and technological breakthroughs, but that will not be enough. Even more critical will be effective collaboration of environmental and physical scientists with social scientists and those in the humanities, active exchange of information among practitioners in academics, politics, religion, and business and other stakeholders, and clear communication of relevant issues and solutions to the general public. This special feature offers examples of how researchers are addressing this grand challenge through the process of discovering new knowledge and relevant tools, transferring insights across disciplinary boundaries, and establishing critical dialogues with those outside academia to help effect positive global change.

  15. The Grand Challenges of WCRP and the Climate Observing System of the Future

    Science.gov (United States)

    Brasseur, G. P.

    2017-12-01

    The successful implementation the Paris agreement on climate change (COP21) calls for a well-designed global monitoring system of essential climate variables, climate processes and Earth system budgets. The Grand Challenges implemented by the World Climate Research Programme (WCRP) provide an opportunity to investigate issues of high societal relevance, directly related to sea level rise, droughts, floods, extreme heat events, food security, and fresh water availability. These challenges would directly benefit from a well-designed suite of systematic climate observations. Quantification of the evolution of the global energy, water and carbon budgets as well as the development and the production of near-term and regional climate predictions require that a comprehensive, focused, multi-platform observing system (satellites, ground-based and in situ observations) be established in an international context. This system must be accompanied by the development of climate services that should translate and disseminate scientific outcomes as actionable information for users and stakeholders.

  16. A Microbial Perspective on the Grand Challenges in Comparative Animal Physiology

    Science.gov (United States)

    2018-01-01

    ABSTRACT Interactions with microbial communities can have profound influences on animal physiology, thereby impacting animal performance and fitness. Therefore, it is important to understand the diversity and nature of host-microbe interactions in various animal groups (invertebrates, fish, amphibians, reptiles, birds, and mammals). In this perspective, I discuss how the field of host-microbe interactions can be used to address topics that have been identified as grand challenges in comparative animal physiology: (i) horizontal integration of physiological processes across organisms, (ii) vertical integration of physiological processes across organizational levels within organisms, and (iii) temporal integration of physiological processes during evolutionary change. Addressing these challenges will require the use of a variety of animal models and the development of systems approaches that can integrate large, multiomic data sets from both microbial communities and animal hosts. Integrating host-microbe interactions into the established field of comparative physiology represents an exciting frontier for both fields. PMID:29556549

  17. Scientific Grand Challenges: Crosscutting Technologies for Computing at the Exascale - February 2-4, 2010, Washington, D.C.

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.

    2011-02-06

    The goal of the "Scientific Grand Challenges - Crosscutting Technologies for Computing at the Exascale" workshop in February 2010, jointly sponsored by the U.S. Department of Energy’s Office of Advanced Scientific Computing Research and the National Nuclear Security Administration, was to identify the elements of a research and development agenda that will address these challenges and create a comprehensive exascale computing environment. This exascale computing environment will enable the science applications identified in the eight previously held Scientific Grand Challenges Workshop Series.

  18. Solving the challenges of extended reach well in Brazil; Vencendo desafios em pocos de grande afastamento

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Vicente Abel S.R.; Araujo, Romero G.S.; N Filho, Aluisio F [PETROBRAS, Rio de Janeiro, RJ (Brazil); Veneziani, Luciano S [Halliburton Servicos Ltda., Macae, RJ (Brazil)

    2004-07-01

    With the objective of minimizing costs and allowing oil to be produced from reservoirs near the coast in shallow waters (i.e. less than 3 meters) which make the use of standard marine units impractical, several Extended Reach Wells were drilled from special land based locations in an area with increased environmental awareness (mangroves and 'Salinas'). This was the reality faced in the 'Serra Field' located on the north coast of the state of Rio Grande do Norte (Brasil) and under the management of the Rio Grande do Norte and Ceara Business Unit of PETROBRAS.The ratio between the actual displacement and vertical depth of these wells is approximately 2.7, with actual displacement a bit greater than 2,600 meters, with the idea of reaching displacements exceeding 3,000 meters in the future. In order to drill these wells, special new technologies were adopted; the drilling rig was upgraded, specific software for the development of the project considering both the reservoir and planning of the well, along with the integration and commitment of the Team to follow, execution and that of the service companies resulted in significant improvements in the Drilling Times. Tools adopted in the design of the well, and in the monitoring of the drilling and completion included Torque and Drag Analysis, Rock Mechanics, Drilling Fluids, Well Trajectory, Anti-Collision, Hydraulics and Wellbore Cleaning. This paper will describe the actions taken, the results, challenges and lessons learned during this Exploration Programme in the Serra Field. (author)

  19. 1st oPAC Topical Workshop: Grand Challenges in Accelerator Optimisation

    CERN Document Server

    2013-01-01

    Accelerators are key instruments for fundamental research, health and industry applications. International collaboration is very important for their continued optimisation. To address this oPAC is organising this two-day international workshop on Grand Challenges in Accelerator Optimisation. The workshop will provide an overview of the current state of the art in beam physics, numerical simulations and beam instrumentation and highlight existing limitations. It will discuss research and development being undertaken and ambitions to further improve the performance of existing and future facilities. In addition to invited talks, there will be industry displays and a special seminar covering recent LHC discoveries. All participants will have an opportunity to contribute a poster.

  20. Managing locality in grand challenge applications: a case study of the gyrokinetic toroidal code

    Energy Technology Data Exchange (ETDEWEB)

    Marin, G; Jin, G; Mellor-Crummey, J [Department of Computer Science, Rice University, Houston, TX 77005 (United States)

    2008-07-15

    Achieving high performance with grand challenge applications on today's large-scale parallel systems requires tailoring applications for the characteristics of the modern microprocessor architectures. As part of the US Department of Energy's Scientific Discovery through Advanced Computing (SciDAC) program, we studied and tuned the Gyrokinetic Toroidal Code (GTC), a particle-in-cell code for simulating turbulent transport of particles and energy in burning plasma, developed at Princeton Plasma Physics Laboratory. In this paper, we present a performance study of the application that revealed several opportunities for improving performance by enhancing its data locality. We tuned GTC by performing three kinds of transformations: static data structure reorganization to improve spatial locality, loop nest restructuring for better temporal locality, and dynamic data reordering at run-time to enhance both spatial and temporal reuse. Experimental results show that these changes improve execution time by more than 20% on large parallel systems, including a Cray XT4.

  1. Managing locality in grand challenge applications: a case study of the gyrokinetic toroidal code

    International Nuclear Information System (INIS)

    Marin, G; Jin, G; Mellor-Crummey, J

    2008-01-01

    Achieving high performance with grand challenge applications on today's large-scale parallel systems requires tailoring applications for the characteristics of the modern microprocessor architectures. As part of the US Department of Energy's Scientific Discovery through Advanced Computing (SciDAC) program, we studied and tuned the Gyrokinetic Toroidal Code (GTC), a particle-in-cell code for simulating turbulent transport of particles and energy in burning plasma, developed at Princeton Plasma Physics Laboratory. In this paper, we present a performance study of the application that revealed several opportunities for improving performance by enhancing its data locality. We tuned GTC by performing three kinds of transformations: static data structure reorganization to improve spatial locality, loop nest restructuring for better temporal locality, and dynamic data reordering at run-time to enhance both spatial and temporal reuse. Experimental results show that these changes improve execution time by more than 20% on large parallel systems, including a Cray XT4

  2. Grand Challenges for Biological and Environmental Research: A Long-Term Vision

    Energy Technology Data Exchange (ETDEWEB)

    Arkin, A.; Baliga, N.; Braam, J.; Church, G.; Collins, J; ; Cottingham, R.; Ecker, J.; Gerstein, M.; Gilna, P.; Greenberg, J.; Handelsman, J.; Hubbard, S.; Joachimiak, A.; Liao, J.; Looger, L.; Meyerowitz, E.; Mjolness, E.; Petsko, G.; Sayler, G.; Simpson, M.; Stacey, G.; Sussman, M.; Tiedje, J.; Bader, D.; Cessi, P.; Collins, W.; Denning, S.; Dickinson, R.; Easterling, D.; Edmonds, J.; Feddema, J.; Field, C.; Fridlind, A.; Fung, I.; Held, I.; Jackson, R.; Janetos, A.; Large, W.; Leinen, M.; Leung, R.; Long, S.; Mace, G.; Masiello, C.; Meehl, G.; Ort, D.; Otto-Bliesner, B.; Penner, J.; Prather, M.; Randall, D.; Rasch, P.; Schneider, E.; Shugart, H.; Thornton, P.; Washington, W.; Wildung, R.; Wiscombe, W.; Zak, D.; Zhang, M.; Bielicki, J.; Buford, M.; Cleland, E.; Dale, V.; Duke, C.; Ehleringer, J.; Hecht, A.; Kammen, D.; Marland, G.; Pataki, D.; Riley, M. Robertson, P.; Hubbard, S.

    2010-12-01

    outcomes and behaviors of complex biological and environmental systems, leading to robust solutions for DOE missions and strategic goals. In March 2010, the Biological and Environmental Research Advisory Committee held the Grand Challenges for Biological and Environmental Research: A Long-Term Vision workshop to identify scientific opportunities and grand challenges for BER science in the coming decades and to develop an overall strategy for drafting a long-term vision for BER. Key workshop goals included: (1) Identifying the greatest scientific challenges in biology, climate, and the environment that DOE will face over a 20-year time horizon. (2) Describing how BER should be positioned to address those challenges. (3) Determining the new and innovative tools needed to advance BER science. (4) Suggesting how the workforce of the future should be trained in integrative system science. This report lays out grand research challenges for BER - in biological systems, climate, energy sustainability, computing, and education and workforce training - that can put society on a path to achieve the scientific evidence and predictive understanding needed to inform decision making and planning to address future energy needs, climate change, water availability, and land use.

  3. Network discovery, characterization, and prediction : a grand challenge LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Kegelmeyer, W. Philip, Jr.

    2010-11-01

    This report is the final summation of Sandia's Grand Challenge LDRD project No.119351, 'Network Discovery, Characterization and Prediction' (the 'NGC') which ran from FY08 to FY10. The aim of the NGC, in a nutshell, was to research, develop, and evaluate relevant analysis capabilities that address adversarial networks. Unlike some Grand Challenge efforts, that ambition created cultural subgoals, as well as technical and programmatic ones, as the insistence on 'relevancy' required that the Sandia informatics research communities and the analyst user communities come to appreciate each others needs and capabilities in a very deep and concrete way. The NGC generated a number of technical, programmatic, and cultural advances, detailed in this report. There were new algorithmic insights and research that resulted in fifty-three refereed publications and presentations; this report concludes with an abstract-annotated bibliography pointing to them all. The NGC generated three substantial prototypes that not only achieved their intended goals of testing our algorithmic integration, but which also served as vehicles for customer education and program development. The NGC, as intended, has catalyzed future work in this domain; by the end it had already brought in, in new funding, as much funding as had been invested in it. Finally, the NGC knit together previously disparate research staff and user expertise in a fashion that not only addressed our immediate research goals, but which promises to have created an enduring cultural legacy of mutual understanding, in service of Sandia's national security responsibilities in cybersecurity and counter proliferation.

  4. CDOCKER and lambda λ -dynamics for prospective prediction in D3R Grand Challenge 2

    Science.gov (United States)

    Ding, Xinqiang; Hayes, Ryan L.; Vilseck, Jonah Z.; Charles, Murchtricia K.; Brooks, Charles L.

    2018-01-01

    The opportunity to prospectively predict ligand bound poses and free energies of binding to the Farnesoid X Receptor in the D3R Grand Challenge 2 provided a useful exercise to evaluate CHARMM based docking (CDOCKER) and λ-dynamics methodologies for use in "real-world" applications in computer aided drug design. In addition to measuring their current performance, several recent methodological developments have been analyzed retrospectively to highlight best procedural practices in future applications. For pose prediction with CDOCKER, when the protein structure used for rigid receptor docking was close to the crystallographic holo structure, reliable poses were obtained. Benzimidazoles, with a known holo receptor structure, were successfully docked with an average RMSD of 0.97 Å. Other non-benzimidazole ligands displayed less accuracy largely because the receptor structures we chose for docking were too different from the experimental holo structures. However, retrospective analysis has shown that when these ligands were re-docked into their holo structures, the average RMSD dropped to 1.18 Å for all ligands. When sulfonamides and spiros were docked with the apo structure, which agrees more with their holo structure than the structures we chose, five out of six ligands were correctly docked. These docking results emphasize the need for flexible receptor docking approaches. For λ-dynamics techniques, including multisite λ-dynamics (MSλD), reasonable agreement with experiment was observed for the 33 ligands investigated; root mean square errors of 2.08 and 1.67 kcal/mol were obtained for free energy sets 1 and 2, respectively. Retrospectively, soft-core potentials, adaptive landscape flattening, and biasing potential replica exchange (BP-REX) algorithms were critical to model large substituent perturbations with sufficient precision and within restrictive timeframes, such as was required with participation in Grand Challenge 2. These developments, their

  5. Development of a Multi-functional Soft Robot (SNUMAX and Performance in RoboSoft Grand Challenge

    Directory of Open Access Journals (Sweden)

    Jun-Young Lee

    2016-10-01

    Full Text Available This paper introduces SNUMAX, the grand winner of the RoboSoft Grand Challenge. SNUMAX was built to complete all the tasks of the challenge. Completing these tasks required robotic compliant components that could adapt to variable situations and environments and generate enough stiffness to maintain performance. SNUMAX has three key components: transformable origami wheels, a polymer-based variable stiffness manipulator, and an adaptive caging gripper. This paper describes the design of these components and how they worked together to allow the robot to perform the contest’s navigation and manipulation tasks.

  6. Team science and the physician-scientist in the age of grand health challenges.

    Science.gov (United States)

    Steer, Clifford J; Jackson, Peter R; Hornbeak, Hortencia; McKay, Catherine K; Sriramarao, P; Murtaugh, Michael P

    2017-09-01

    Despite remarkable advances in medical research, clinicians face daunting challenges from new diseases, variations in patient responses to interventions, and increasing numbers of people with chronic health problems. The gap between biomedical research and unmet clinical needs can be addressed by highly talented interdisciplinary investigators focused on translational bench-to-bedside medicine. The training of talented physician-scientists comfortable with forming and participating in multidisciplinary teams that address complex health problems is a top national priority. Challenges, methods, and experiences associated with physician-scientist training and team building were explored at a workshop held at the Second International Conference on One Medicine One Science (iCOMOS 2016), April 24-27, 2016, in Minneapolis, Minnesota. A broad range of scientists, regulatory authorities, and health care experts determined that critical investments in interdisciplinary training are essential for the future of medicine and healthcare delivery. Physician-scientists trained in a broad, nonlinear, cross-disciplinary manner are and will be essential members of science teams in the new age of grand health challenges and the birth of precision medicine. Team science approaches have accomplished biomedical breakthroughs once considered impossible, and dedicated physician-scientists have been critical to these achievements. Together, they translate into the pillars of academic growth and success. © 2017 New York Academy of Sciences.

  7. Solving the challenges of extended reach well in Brazil; Vencendo desafios em pocos de grande afastamento

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Vicente Abel S.R.; Araujo, Romero G.S.; N. Filho, Aluisio F. [PETROBRAS, Rio de Janeiro, RJ (Brazil); Veneziani, Luciano S. [Halliburton Servicos Ltda., Macae, RJ (Brazil)

    2004-07-01

    With the objective of minimizing costs and allowing oil to be produced from reservoirs near the coast in shallow waters (i.e. less than 3 meters) which make the use of standard marine units impractical, several Extended Reach Wells were drilled from special land based locations in an area with increased environmental awareness (mangroves and 'Salinas'). This was the reality faced in the 'Serra Field' located on the north coast of the state of Rio Grande do Norte (Brasil) and under the management of the Rio Grande do Norte and Ceara Business Unit of PETROBRAS.The ratio between the actual displacement and vertical depth of these wells is approximately 2.7, with actual displacement a bit greater than 2,600 meters, with the idea of reaching displacements exceeding 3,000 meters in the future. In order to drill these wells, special new technologies were adopted; the drilling rig was upgraded, specific software for the development of the project considering both the reservoir and planning of the well, along with the integration and commitment of the Team to follow, execution and that of the service companies resulted in significant improvements in the Drilling Times. Tools adopted in the design of the well, and in the monitoring of the drilling and completion included Torque and Drag Analysis, Rock Mechanics, Drilling Fluids, Well Trajectory, Anti-Collision, Hydraulics and Wellbore Cleaning. This paper will describe the actions taken, the results, challenges and lessons learned during this Exploration Programme in the Serra Field. (author)

  8. Addressing China's grand challenge of achieving food security while ensuring environmental sustainability.

    Science.gov (United States)

    Lu, Yonglong; Jenkins, Alan; Ferrier, Robert C; Bailey, Mark; Gordon, Iain J; Song, Shuai; Huang, Jikun; Jia, Shaofeng; Zhang, Fusuo; Liu, Xuejun; Feng, Zhaozhong; Zhang, Zhibin

    2015-02-01

    China's increasingly urbanized and wealthy population is driving a growing and changing demand for food, which might not be met without significant increase in agricultural productivity and sustainable use of natural resources. Given the past relationship between lack of access to affordable food and political instability, food security has to be given a high priority on national political agendas in the context of globalization. The drive for increased food production has had a significant impact on the environment, and the deterioration in ecosystem quality due to historic and current levels of pollution will potentially compromise the food production system in China. We discuss the grand challenges of not only producing more food but also producing it sustainably and without environmental degradation. In addressing these challenges, food production should be considered as part of an environmental system (soil, air, water, and biodiversity) and not independent from it. It is imperative that new ways of meeting the demand for food are developed while safeguarding the natural resources upon which food production is based. We present a holistic approach to both science and policy to ensure future food security while embracing the ambition of achieving environmental sustainability in China. It is a unique opportunity for China to be a role model as a new global player, especially for other emerging economies.

  9. New capabilities in the HENP grand challenge storage access system and its application at RHIC

    International Nuclear Information System (INIS)

    Bernardo, L.; Gibbard, B.; Malon, D.; Nordberg, H.; Olson, D.; Porter, R.; Shoshani, A.; Sim, A.; Vaniachine, A.; Wenaus, T.; Wu, K.; Zimmerman, D.

    2000-01-01

    The High Energy and Nuclear Physics Data Access Grand Challenge project has developed an optimizing storage access software system that was prototyped at RHIC. It is currently undergoing integration with the STAR experiment in preparation for data taking that starts in mid-2000. The behavior and lessons learned in the RHIC Mock Data Challenge exercises are described as well as the observed performance under conditions designed to characterize scalability. Up to 250 simultaneous queries were tested and up to 10 million events across 7 event components were involved in these queries. The system coordinates the staging of ''bundles'' of files from the HPSS tape system, so that all the needed components of each event are in disk cache when accessed by the application software. The caching policy algorithm for the coordinated bundle staging is described in the paper. The initial prototype implementation interfaced to the Objectivity/DB. In this latest version, it evolved to work with arbitrary files and use CORBA interfaces to the tag database and file catalog services. The interface to the tag database and the MySQL-based file catalog services used by STAR are described along with the planned usage scenarios

  10. Groundwater Challenges of the Lower Rio Grande: A Case Study of Legal Issues in Texas and New Mexico

    Directory of Open Access Journals (Sweden)

    Elizabeth Wheat

    2015-03-01

    Full Text Available In 1938, Texas, New Mexico, and Colorado signed the Rio Grande Compact, establishing terms of apportionment for some of the water from the Rio Grande for the three states. Following congressional approval in 1939, this compact governs water allocation in a region with a variable climate and frequent drought conditions and established the Rio Grande Compact Commission, comprised of a commissioner from each state and one from the federal government, to enforce the compact. With an increasing population and declining surface water supply, the Compact has been tested among the parties and within the states themselves. In a case currently before the U.S. Supreme Court, Texas v. New Mexico and Colorado (2013, Texas claims New Mexico is violating the Compact and Rio Grande Project Act by using water in excess of its apportionment through its allowance of diversions of surface and groundwater. The issue is further compounded by disputes within Texas over separate legal regimes for groundwater and surface water. Combined with growing scarcity issues, the allocation of water in the Lower Rio Grande presents a timely natural resource challenge. This review explores legal issues involved in the case as well as growing challenges of population growth, agricultural development needs, and water shortages.

  11. The Grand Challenge of Basin-Scale Groundwater Quality Management Modelling

    Science.gov (United States)

    Fogg, G. E.

    2017-12-01

    The last 50+ years of agricultural, urban and industrial land and water use practices have accelerated the degradation of groundwater quality in the upper portions of many major aquifer systems upon which much of the world relies for water supply. In the deepest and most extensive systems (e.g., sedimentary basins) that typically have the largest groundwater production rates and hold fresh groundwaters on decadal to millennial time scales, most of the groundwater is not yet contaminated. Predicting the long-term future groundwater quality in such basins is a grand scientific challenge. Moreover, determining what changes in land and water use practices would avert future, irreversible degradation of these massive freshwater stores is a grand challenge both scientifically and societally. It is naïve to think that the problem can be solved by eliminating or reducing enough of the contaminant sources, for human exploitation of land and water resources will likely always result in some contamination. The key lies in both reducing the contaminant sources and more proactively managing recharge in terms of both quantity and quality, such that the net influx of contaminants is sufficiently moderate and appropriately distributed in space and time to reverse ongoing groundwater quality degradation. Just as sustainable groundwater quantity management is greatly facilitated with groundwater flow management models, sustainable groundwater quality management will require the use of groundwater quality management models. This is a new genre of hydrologic models do not yet exist, partly because of the lack of modeling tools and the supporting research to model non-reactive as well as reactive transport on large space and time scales. It is essential that the contaminant hydrogeology community, which has heretofore focused almost entirely on point-source plume-scale problems, direct it's efforts toward the development of process-based transport modeling tools and analyses capable

  12. On the added value of forensic science and grand innovation challenges for the forensic community.

    Science.gov (United States)

    van Asten, Arian C

    2014-03-01

    In this paper the insights and results are presented of a long term and ongoing improvement effort within the Netherlands Forensic Institute (NFI) to establish a valuable innovation programme. From the overall perspective of the role and use of forensic science in the criminal justice system, the concepts of Forensic Information Value Added (FIVA) and Forensic Information Value Efficiency (FIVE) are introduced. From these concepts the key factors determining the added value of forensic investigations are discussed; Evidential Value, Relevance, Quality, Speed and Cost. By unravelling the added value of forensic science and combining this with the future needs and scientific and technological developments, six forensic grand challenges are introduced: i) Molecular Photo-fitting; ii) chemical imaging, profiling and age estimation of finger marks; iii) Advancing Forensic Medicine; iv) Objective Forensic Evaluation; v) the Digital Forensic Service Centre and vi) Real time In-Situ Chemical Identification. Finally, models for forensic innovation are presented that could lead to major international breakthroughs on all these six themes within a five year time span. This could cause a step change in the added value of forensic science and would make forensic investigative methods even more valuable than they already are today. © 2013. Published by Elsevier Ireland Ltd on behalf of Forensic Science Society. All rights reserved.

  13. Hyperresolution global land surface modeling: Meeting a grand challenge for monitoring Earth's terrestrial water

    Science.gov (United States)

    Wood, Eric F.; Roundy, Joshua K.; Troy, Tara J.; van Beek, L. P. H.; Bierkens, Marc F. P.; Blyth, Eleanor; de Roo, Ad; DöLl, Petra; Ek, Mike; Famiglietti, James; Gochis, David; van de Giesen, Nick; Houser, Paul; Jaffé, Peter R.; Kollet, Stefan; Lehner, Bernhard; Lettenmaier, Dennis P.; Peters-Lidard, Christa; Sivapalan, Murugesu; Sheffield, Justin; Wade, Andrew; Whitehead, Paul

    2011-05-01

    Monitoring Earth's terrestrial water conditions is critically important to many hydrological applications such as global food production; assessing water resources sustainability; and flood, drought, and climate change prediction. These needs have motivated the development of pilot monitoring and prediction systems for terrestrial hydrologic and vegetative states, but to date only at the rather coarse spatial resolutions (˜10-100 km) over continental to global domains. Adequately addressing critical water cycle science questions and applications requires systems that are implemented globally at much higher resolutions, on the order of 1 km, resolutions referred to as hyperresolution in the context of global land surface models. This opinion paper sets forth the needs and benefits for a system that would monitor and predict the Earth's terrestrial water, energy, and biogeochemical cycles. We discuss six major challenges in developing a system: improved representation of surface-subsurface interactions due to fine-scale topography and vegetation; improved representation of land-atmospheric interactions and resulting spatial information on soil moisture and evapotranspiration; inclusion of water quality as part of the biogeochemical cycle; representation of human impacts from water management; utilizing massively parallel computer systems and recent computational advances in solving hyperresolution models that will have up to 109 unknowns; and developing the required in situ and remote sensing global data sets. We deem the development of a global hyperresolution model for monitoring the terrestrial water, energy, and biogeochemical cycles a "grand challenge" to the community, and we call upon the international hydrologic community and the hydrological science support infrastructure to endorse the effort.

  14. Grand challenges in understanding the interplay of climate and land changes

    Science.gov (United States)

    Liu, Shuguang; Bond-Lamberty, Ben; Boysen, Lena R.; Ford, James D.; Fox, Andrew; Gallo, Kevin; Hatfield, Jerry L.; Henebry, Geoffrey M.; Huntington, Thomas G.; Liu, Zhihua; Loveland, Thomas R.; Norby, Richard J.; Sohl, Terry L.; Steiner, Allison L.; Yuan, Wenping; Zhang, Zhao; Zhao, Shuqing

    2017-01-01

    Half of Earth’s land surface has been altered by human activities, creating various consequences on the climate and weather systems at local to global scales, which in turn affect a myriad of land surface processes and the adaptation behaviors. This study reviews the status and major knowledge gaps in the interactions of land and atmospheric changes and present 11 grand challenge areas for the scientific research and adaptation community in the coming decade. These land-cover and land-use change (LCLUC)-related areas include 1) impacts on weather and climate, 2) carbon and other biogeochemical cycles, 3) biospheric emissions, 4) the water cycle, 5) agriculture, 6) urbanization, 7) acclimation of biogeochemical processes to climate change, 8) plant migration, 9) land-use projections, 10) model and data uncertainties, and, finally, 11) adaptation strategies. Numerous studies have demonstrated the effects of LCLUC on local to global climate and weather systems, but these putative effects vary greatly in magnitude and even sign across space, time, and scale and thus remain highly uncertain. At the same time, many challenges exist toward improved understanding of the consequences of atmospheric and climate change on land process dynamics and services. Future effort must improve the understanding of the scale-dependent, multifaceted perturbations and feedbacks between land and climate changes in both reality and models. To this end, one critical cross-disciplinary need is to systematically quantify and better understand measurement and model uncertainties. Finally, LCLUC mitigation and adaptation assessments must be strengthened to identify implementation barriers, evaluate and prioritize opportunities, and examine how decision-making processes work in specific contexts.

  15. Hyperresolution Global Land Surface Modeling: Meeting a Grand Challenge for Monitoring Earth's Terrestrial Water

    Science.gov (United States)

    Wood, Eric F.; Roundy, Joshua K.; Troy, Tara J.; van Beek, L. P. H.; Bierkens, Marc F. P.; 4 Blyth, Eleanor; de Roo, Ad; Doell. Petra; Ek, Mike; Famiglietti, James; hide

    2011-01-01

    Monitoring Earth's terrestrial water conditions is critically important to many hydrological applications such as global food production; assessing water resources sustainability; and flood, drought, and climate change prediction. These needs have motivated the development of pilot monitoring and prediction systems for terrestrial hydrologic and vegetative states, but to date only at the rather coarse spatial resolutions (approx.10-100 km) over continental to global domains. Adequately addressing critical water cycle science questions and applications requires systems that are implemented globally at much higher resolutions, on the order of 1 km, resolutions referred to as hyperresolution in the context of global land surface models. This opinion paper sets forth the needs and benefits for a system that would monitor and predict the Earth's terrestrial water, energy, and biogeochemical cycles. We discuss six major challenges in developing a system: improved representation of surface-subsurface interactions due to fine-scale topography and vegetation; improved representation of land-atmospheric interactions and resulting spatial information on soil moisture and evapotranspiration; inclusion of water quality as part of the biogeochemical cycle; representation of human impacts from water management; utilizing massively parallel computer systems and recent computational advances in solving hyperresolution models that will have up to 10(exp 9) unknowns; and developing the required in situ and remote sensing global data sets. We deem the development of a global hyperresolution model for monitoring the terrestrial water, energy, and biogeochemical cycles a grand challenge to the community, and we call upon the international hydrologic community and the hydrological science support infrastructure to endorse the effort.

  16. Comparative psychology and the grand challenge of drug discovery in psychiatry and neurodegeneration.

    Science.gov (United States)

    Brunner, Dani; Balcı, Fuat; Ludvig, Elliot A

    2012-02-01

    Drug discovery for brain disorders is undergoing a period of upheaval. Faced with an empty drug pipeline and numerous failures of potential new drugs in clinical trials, many large pharmaceutical companies have been shrinking or even closing down their research divisions that focus on central nervous system (CNS) disorders. In this paper, we argue that many of the difficulties facing CNS drug discovery stem from a lack of robustness in pre-clinical (i.e., non-human animal) testing. There are two main sources for this lack of robustness. First, there is the lack of replicability of many results from the pre-clinical stage, which we argue is driven by a combination of publication bias and inappropriate selection of statistical and experimental designs. Second, there is the frequent failure to translate results in non-human animals to parallel results in humans in the clinic. This limitation can only be overcome by developing new behavioral tests for non-human animals that have predictive, construct, and etiological validity. Here, we present these translational difficulties as a "grand challenge" to researchers from comparative cognition, who are well positioned to provide new methods for testing behavior and cognition in non-human animals. These new experimental protocols will need to be both statistically robust and target behavioral and cognitive processes that allow for better connection with human CNS disorders. Our hope is that this downturn in industrial research may represent an opportunity to develop new protocols that will re-kindle the search for more effective and safer drugs for CNS disorders. Copyright © 2011 Elsevier B.V. All rights reserved.

  17. Permeable Binaries, Societal Grand Challenges, and the Roles of the Twenty-first-century Archival and Recordkeeping Profession

    OpenAIRE

    Gilliland, AJ

    2015-01-01

    Building upon recent work, this paper demonstrates how 21st century recordkeeping concerns are integral to societal grand challenges that have been identified by governments, think tanks, scholarly organisations and affected communities around the globe. Using the example of forced displacement and migration the paper focuses on ways in which recordkeeping is inextricably linked to both the causes and possible digital, policy and educational mechanisms for addressing certain aspects of societ...

  18. Thermal Protection for Mars Sample Return Earth Entry Vehicle: A Grand Challenge for Design Methodology and Reliability Verification

    Science.gov (United States)

    Venkatapathy, Ethiraj; Gage, Peter; Wright, Michael J.

    2017-01-01

    Mars Sample Return is our Grand Challenge for the coming decade. TPS (Thermal Protection System) nominal performance is not the key challenge. The main difficulty for designers is the need to verify unprecedented reliability for the entry system: current guidelines for prevention of backward contamination require that the probability of spores larger than 1 micron diameter escaping into the Earth environment be lower than 1 million for the entire system, and the allocation to TPS would be more stringent than that. For reference, the reliability allocation for Orion TPS is closer to 11000, and the demonstrated reliability for previous human Earth return systems was closer to 1100. Improving reliability by more than 3 orders of magnitude is a grand challenge indeed. The TPS community must embrace the possibility of new architectures that are focused on reliability above thermal performance and mass efficiency. MSR (Mars Sample Return) EEV (Earth Entry Vehicle) will be hit with MMOD (Micrometeoroid and Orbital Debris) prior to reentry. A chute-less aero-shell design which allows for self-righting shape was baselined in prior MSR studies, with the assumption that a passive system will maximize EEV robustness. Hence the aero-shell along with the TPS has to take ground impact and not break apart. System verification will require testing to establish ablative performance and thermal failure but also testing of damage from MMOD, and structural performance at ground impact. Mission requirements will demand analysis, testing and verification that are focused on establishing reliability of the design. In this proposed talk, we will focus on the grand challenge of MSR EEV TPS and the need for innovative approaches to address challenges in modeling, testing, manufacturing and verification.

  19. D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies

    Science.gov (United States)

    Gaieb, Zied; Liu, Shuai; Gathiaka, Symon; Chiu, Michael; Yang, Huanwang; Shao, Chenghua; Feher, Victoria A.; Walters, W. Patrick; Kuhn, Bernd; Rudolph, Markus G.; Burley, Stephen K.; Gilson, Michael K.; Amaro, Rommie E.

    2018-01-01

    The Drug Design Data Resource (D3R) ran Grand Challenge 2 (GC2) from September 2016 through February 2017. This challenge was based on a dataset of structures and affinities for the nuclear receptor farnesoid X receptor (FXR), contributed by F. Hoffmann-La Roche. The dataset contained 102 IC50 values, spanning six orders of magnitude, and 36 high-resolution co-crystal structures with representatives of four major ligand classes. Strong global participation was evident, with 49 participants submitting 262 prediction submission packages in total. Procedurally, GC2 mimicked Grand Challenge 2015 (GC2015), with a Stage 1 subchallenge testing ligand pose prediction methods and ranking and scoring methods, and a Stage 2 subchallenge testing only ligand ranking and scoring methods after the release of all blinded co-crystal structures. Two smaller curated sets of 18 and 15 ligands were developed to test alchemical free energy methods. This overview summarizes all aspects of GC2, including the dataset details, challenge procedures, and participant results. We also consider implications for progress in the field, while highlighting methodological areas that merit continued development. Similar to GC2015, the outcome of GC2 underscores the pressing need for methods development in pose prediction, particularly for ligand scaffolds not currently represented in the Protein Data Bank (http://www.pdb.org), and in affinity ranking and scoring of bound ligands.

  20. Grand Challenges of Advanced Computing for Energy Innovation Report from the Workshop Held July 31-August 2, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Larzelere, Alex R.; Ashby, Steven F.; Christensen, Dana C.; Crawford, Dona L.; Khaleel, Mohammad A.; John, Grosh; Stults, B. Ray; Lee, Steven L.; Hammond, Steven W.; Grover, Benjamin T.; Neely, Rob; Dudney, Lee Ann; Goldstein, Noah C.; Wells, Jack; Peltz, Jim

    2013-03-06

    On July 31-August 2 of 2012, the U.S. Department of Energy (DOE) held a workshop entitled Grand Challenges of Advanced Computing for Energy Innovation. This workshop built on three earlier workshops that clearly identified the potential for the Department and its national laboratories to enable energy innovation. The specific goal of the workshop was to identify the key challenges that the nation must overcome to apply the full benefit of taxpayer-funded advanced computing technologies to U.S. energy innovation in the ways that the country produces, moves, stores, and uses energy. Perhaps more importantly, the workshop also developed a set of recommendations to help the Department overcome those challenges. These recommendations provide an action plan for what the Department can do in the coming years to improve the nation’s energy future.

  1. Search of the Deep and Dark Web via DARPA Memex

    Science.gov (United States)

    Mattmann, C. A.

    2015-12-01

    Search has progressed through several stages due to the increasing size of the Web. Search engines first focused on text and its rate of occurrence; then focused on the notion of link analysis and citation then on interactivity and guided search; and now on the use of social media - who we interact with, what we comment on, and who we follow (and who follows us). The next stage, referred to as "deep search," requires solutions that can bring together text, images, video, importance, interactivity, and social media to solve this challenging problem. The Apache Nutch project provides an open framework for large-scale, targeted, vertical search with capabilities to support all past and potential future search engine foci. Nutch is a flexible infrastructure allowing open access to ranking; URL selection and filtering approaches, to the link graph generated from search, and Nutch has spawned entire sub communities including Apache Hadoop and Apache Tika. It addresses many current needs with the capability to support new technologies such as image and video. On the DARPA Memex project, we are creating create specific extensions to Nutch that will directly improve its overall technological superiority for search and that will directly allow us to address complex search problems including human trafficking. We are integrating state-of-the-art algorithms developed by Kitware for IARPA Aladdin combined with work by Harvard to provide image and video understanding support allowing automatic detection of people and things and massive deployment via Nutch. We are expanding Apache Tika for scene understanding, object/person detection and classification in images/video. We are delivering an interactive and visual interface for initiating Nutch crawls. The interface uses Python technologies to expose Nutch data and to provide a domain specific language for crawls. With the Bokeh visualization library the interface we are delivering simple interactive crawl visualization and

  2. The Gap Frame - Enriching the SDG Compass by translating the SDGs into relevant national Grand Challenges for strategic business opportunities

    OpenAIRE

    Muff, Katrin; Kapalka, Agnieszka; Dyllick, Thomas

    2017-01-01

    The global agenda of Grand Challenges until 2030 is set: the Sustainable Development Goals (SDGs) enjoy broad global governmental acceptance and increasing business awareness. This paper takes a concrete look at how we can reach a state-of-the-world by 2030 that is ‘safe for all of us’. Getting there requires relevant national measures that are easily accessible for business, which is considered a key transformative force with its innovation power. The global nature and focus of the SDGs make...

  3. Phase I Report: DARPA Exoskeleton Program

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, J.F.

    2004-01-21

    The Defense Advanced Research Projects Agency (DARPA) inaugurated a program addressing research and development for an Exoskeleton for Human Performance Augmentation in FY!2001. A team consisting of Oak Ridge National Laboratory, the prime contractor, AeroVironment, Inc., the Army Research Laboratory, the University of Minnesota, and the Virginia Polytechnic Institute has recently completed an 18-month Phase I effort in support of this DARPA program. The Phase I effort focused on the development and proof-of-concept demonstrations for key enabling technologies, laying the foundation for subsequently building and demonstrating a prototype exoskeleton. The overall approach was driven by the need to optimize energy efficiency while providing a system that augmented the operator in as transparent manner as possible (non-impeding). These needs led to the evolution of two key distinguishing features of this team's approach. The first is the ''no knee contact'' concept. This concept is dependent on a unique Cartesian-based control scheme that uses force sensing at the foot and backpack attachments to allow the exoskeleton to closely follow the operator while avoiding the difficulty of connecting and sensing position at the knee. The second is an emphasis on energy efficiency manifested by an energetic, power, actuation and controls approach designed to enhance energy efficiency as well as a reconfigurable kinematic structure that provides a non-anthropomorphic configuration to support an energy saving long-range march/transport mode. The enabling technologies addressed in the first phase were controls and sensing, the soft tissue interface between the machine and the operator, the power system, and actuation. The controller approach was implemented and demonstrated on a test stand with an actual operator. Control stability, low operator fatigue, force amplification and the human interface were all successfully demonstrated, validating the controls

  4. Evaluation and comparison of current fetal ultrasound image segmentation methods for biometric measurements: a grand challenge.

    Science.gov (United States)

    Rueda, Sylvia; Fathima, Sana; Knight, Caroline L; Yaqub, Mohammad; Papageorghiou, Aris T; Rahmatullah, Bahbibi; Foi, Alessandro; Maggioni, Matteo; Pepe, Antonietta; Tohka, Jussi; Stebbing, Richard V; McManigle, John E; Ciurte, Anca; Bresson, Xavier; Cuadra, Meritxell Bach; Sun, Changming; Ponomarev, Gennady V; Gelfand, Mikhail S; Kazanov, Marat D; Wang, Ching-Wei; Chen, Hsiang-Chou; Peng, Chun-Wei; Hung, Chu-Mei; Noble, J Alison

    2014-04-01

    This paper presents the evaluation results of the methods submitted to Challenge US: Biometric Measurements from Fetal Ultrasound Images, a segmentation challenge held at the IEEE International Symposium on Biomedical Imaging 2012. The challenge was set to compare and evaluate current fetal ultrasound image segmentation methods. It consisted of automatically segmenting fetal anatomical structures to measure standard obstetric biometric parameters, from 2D fetal ultrasound images taken on fetuses at different gestational ages (21 weeks, 28 weeks, and 33 weeks) and with varying image quality to reflect data encountered in real clinical environments. Four independent sub-challenges were proposed, according to the objects of interest measured in clinical practice: abdomen, head, femur, and whole fetus. Five teams participated in the head sub-challenge and two teams in the femur sub-challenge, including one team who tackled both. Nobody attempted the abdomen and whole fetus sub-challenges. The challenge goals were two-fold and the participants were asked to submit the segmentation results as well as the measurements derived from the segmented objects. Extensive quantitative (region-based, distance-based, and Bland-Altman measurements) and qualitative evaluation was performed to compare the results from a representative selection of current methods submitted to the challenge. Several experts (three for the head sub-challenge and two for the femur sub-challenge), with different degrees of expertise, manually delineated the objects of interest to define the ground truth used within the evaluation framework. For the head sub-challenge, several groups produced results that could be potentially used in clinical settings, with comparable performance to manual delineations. The femur sub-challenge had inferior performance to the head sub-challenge due to the fact that it is a harder segmentation problem and that the techniques presented relied more on the femur's appearance.

  5. The DARPA manufacturing initiative in high temperature superconductivity

    International Nuclear Information System (INIS)

    Adams, K.R.

    1989-01-01

    The Defense Advanced Research Projects Agency (DARPA) has a very aggressive Technology Base program in high temperature superconductivity. This program is expected to provide the basis for a specialized set of military products - passive microwave and millimeter wave devices - within the next three years. In order to get these high leverage products into military systems, a manufacturing base must be developed for HTSC components. A plan for DARPA in HTSC manufacturing is directly coupled with the ongoing DARPA materials and device oriented R and D program. In essence, this plan recommends a three phased effort: 1. Phase I (two years); Fund companies through R and D contracts for specialized HTSC components; prepare a detailed plan and develop an HTSC consortium. 2. Phase II (six years): Establish an HTSC Sematech initiative for electronic applications, including active devices. 3. Phase III (optional): Continue the HTSC Sematech with emphasis on high power applications

  6. A Case Study in Competitive Technical and Market Intelligence Support and Lessons Learned for the uChemLab LDRD Grand Challenge Project; TOPICAL

    International Nuclear Information System (INIS)

    SOUTHWELL, EDWIN T.; GARCIA, MARIE L.; MEYERS, CHARLES E.

    2001-01-01

    The(mu)ChemLab(trademark) Laboratory Directed Research and Development (LDRD) Grand Challenge project began in October 1996 and ended in September 2000. The technical managers of the(mu)ChemLab(trademark) project and the LDRD office, with the support of a consultant, conducted a competitive technical and market demand intelligence analysis of the(mu)ChemLab(trademark). The managers used this knowledge to make project decisions and course adjustments. CTI/MDI positively impacted the project's technology development, uncovered potential technology partnerships, and supported eventual industry partner contacts. CTI/MDI analysis is now seen as due diligence and the(mu)ChemLab(trademark) project is now the model for other Sandia LDRD Grand Challenge undertakings. This document describes the CTI/MDI analysis and captures the more important ''lessons learned'' of this Grand Challenge project, as reported by the project's management team

  7. Lessons learned in induced fit docking and metadynamics in the Drug Design Data Resource Grand Challenge 2

    Science.gov (United States)

    Baumgartner, Matthew P.; Evans, David A.

    2018-01-01

    Two of the major ongoing challenges in computational drug discovery are predicting the binding pose and affinity of a compound to a protein. The Drug Design Data Resource Grand Challenge 2 was developed to address these problems and to drive development of new methods. The challenge provided the 2D structures of compounds for which the organizers help blinded data in the form of 35 X-ray crystal structures and 102 binding affinity measurements and challenged participants to predict the binding pose and affinity of the compounds. We tested a number of pose prediction methods as part of the challenge; we found that docking methods that incorporate protein flexibility (Induced Fit Docking) outperformed methods that treated the protein as rigid. We also found that using binding pose metadynamics, a molecular dynamics based method, to score docked poses provided the best predictions of our methods with an average RMSD of 2.01 Å. We tested both structure-based (e.g. docking) and ligand-based methods (e.g. QSAR) in the affinity prediction portion of the competition. We found that our structure-based methods based on docking with Smina (Spearman ρ = 0.614), performed slightly better than our ligand-based methods (ρ = 0.543), and had equivalent performance with the other top methods in the competition. Despite the overall good performance of our methods in comparison to other participants in the challenge, there exists significant room for improvement especially in cases such as these where protein flexibility plays such a large role.

  8. Governance Challenges in Joint Inter-Jurisdictional Management: The Grand Teton National Park, Wyoming, Elk Case

    Science.gov (United States)

    Clark, Susan G.; Vernon, Marian E.

    2015-08-01

    The controversial elk reduction program (elk hunt) in Grand Teton National Park, WY, has been a source of conflict since it was legislated in 1950. The hunt is jointly managed by the National Park Service and the Wyoming Game and Fish Department. This forced organizational partnership and the conflicting mandates of these two agencies have led to persistent conflict that seems irresolvable under the current decision-making process. To better understand the decision-making process and participant perspectives, we reviewed management documents, technical literature, and newspaper articles, and interviewed 35 key participants in this case. We used these data to analyze and appraise the adequacy of the decision-making process for the park elk hunt and to ask whether it reflects the common interest. We found deficiencies in all functions of the decision-making process. Neither the decisions made nor the process itself include diverse perspectives, nor do they attend to valid and appropriate participant concerns. Agency officials focus their attention on technical rather than procedural concerns, which largely obfuscates the underlying tension in the joint inter-jurisdictional management arrangement and ultimately contributes to the hunt's annual implementation to the detriment of the common interest. We offer specific yet widely applicable recommendations to better approximate an inclusive and democratic decision-making process that serves the community's common interests.

  9. Relative binding affinity prediction of farnesoid X receptor in the D3R Grand Challenge 2 using FEP+

    Science.gov (United States)

    Schindler, Christina; Rippmann, Friedrich; Kuhn, Daniel

    2018-01-01

    Physics-based free energy simulations have increasingly become an important tool for predicting binding affinity and the recent introduction of automated protocols has also paved the way towards a more widespread use in the pharmaceutical industry. The D3R 2016 Grand Challenge 2 provided an opportunity to blindly test the commercial free energy calculation protocol FEP+ and assess its performance relative to other affinity prediction methods. The present D3R free energy prediction challenge was built around two experimental data sets involving inhibitors of farnesoid X receptor (FXR) which is a promising anticancer drug target. The FXR binding site is predominantly hydrophobic with few conserved interaction motifs and strong induced fit effects making it a challenging target for molecular modeling and drug design. For both data sets, we achieved reasonable prediction accuracy (RMSD ≈ 1.4 kcal/mol, rank 3-4 according to RMSD out of 20 submissions) comparable to that of state-of-the-art methods in the field. Our D3R results boosted our confidence in the method and strengthen our desire to expand its applications in future in-house drug design projects.

  10. Relative binding affinity prediction of farnesoid X receptor in the D3R Grand Challenge 2 using FEP.

    Science.gov (United States)

    Schindler, Christina; Rippmann, Friedrich; Kuhn, Daniel

    2018-01-01

    Physics-based free energy simulations have increasingly become an important tool for predicting binding affinity and the recent introduction of automated protocols has also paved the way towards a more widespread use in the pharmaceutical industry. The D3R 2016 Grand Challenge 2 provided an opportunity to blindly test the commercial free energy calculation protocol FEP+ and assess its performance relative to other affinity prediction methods. The present D3R free energy prediction challenge was built around two experimental data sets involving inhibitors of farnesoid X receptor (FXR) which is a promising anticancer drug target. The FXR binding site is predominantly hydrophobic with few conserved interaction motifs and strong induced fit effects making it a challenging target for molecular modeling and drug design. For both data sets, we achieved reasonable prediction accuracy (RMSD ≈ 1.4 kcal/mol, rank 3-4 according to RMSD out of 20 submissions) comparable to that of state-of-the-art methods in the field. Our D3R results boosted our confidence in the method and strengthen our desire to expand its applications in future in-house drug design projects.

  11. Scientific Grand Challenges: Challenges in Climate Change Science and the Role of Computing at the Extreme Scale

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.; Johnson, Gary M.; Washington, Warren M.

    2009-07-02

    The U.S. Department of Energy (DOE) Office of Biological and Environmental Research (BER) in partnership with the Office of Advanced Scientific Computing Research (ASCR) held a workshop on the challenges in climate change science and the role of computing at the extreme scale, November 6-7, 2008, in Bethesda, Maryland. At the workshop, participants identified the scientific challenges facing the field of climate science and outlined the research directions of highest priority that should be pursued to meet these challenges. Representatives from the national and international climate change research community as well as representatives from the high-performance computing community attended the workshop. This group represented a broad mix of expertise. Of the 99 participants, 6 were from international institutions. Before the workshop, each of the four panels prepared a white paper, which provided the starting place for the workshop discussions. These four panels of workshop attendees devoted to their efforts the following themes: Model Development and Integrated Assessment; Algorithms and Computational Environment; Decadal Predictability and Prediction; Data, Visualization, and Computing Productivity. The recommendations of the panels are summarized in the body of this report.

  12. An overview of DARPA's advanced space technology program

    Science.gov (United States)

    Nicastri, E.; Dodd, J.

    1993-02-01

    The Defense Advanced Research Projects Agency (DARPA) is the central research and development organization of the DoD and, as such, has the primary responsibility for the maintenance of U.S. technological superiority over potential adversaries. DARPA's programs focus on technology development and proof-of-concept demonstrations of both evolutionary and revolutionary approaches for improved strategic, conventional, rapid deployment and sea power forces, and on the scientific investigation into advanced basic technologies of the future. DARPA can move quickly to exploit new ideas and concepts by working directly with industry and universities. For four years, DARPA's Advanced Space Technology Program (ASTP) has addressed various ways to improve the performance of small satellites and launch vehicles. The advanced technologies that are being and will be developed by DARPA for small satellites can be used just as easily on large satellites. The primary objective of the ASTP is to enhance support to operational commanders by developing and applying advanced technologies that will provide cost-effective, timely, flexible, and responsive space systems. Fundamental to the ASTP effort is finding new ways to do business with the goal of quickly inserting new technologies into DoD space systems while reducing cost. In our view, these methods are prime examples of what may be termed 'technology leveraging.' The ASTP has initiated over 50 technology projects, many of which were completed and transitioned to users. The objectives are to quickly qualify these higher risk technologies for use on future programs and reduce the risk of inserting these technologies into major systems, and to provide the miniaturized systems that would enable smaller satellites to have significant - rather than limited - capability. Only a few of the advanced technologies are described, the majority of which are applicable to both large and small satellites.

  13. The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation.

    Science.gov (United States)

    Lewis, Jedediah K; Bischof, John C; Braslavsky, Ido; Brockbank, Kelvin G M; Fahy, Gregory M; Fuller, Barry J; Rabin, Yoed; Tocchio, Alessandro; Woods, Erik J; Wowk, Brian G; Acker, Jason P; Giwa, Sebastian

    2016-04-01

    The first Organ Banking Summit was convened from Feb. 27 - March 1, 2015 in Palo Alto, CA, with events at Stanford University, NASA Research Park, and Lawrence Berkeley National Labs. Experts at the summit outlined the potential public health impact of organ banking, discussed the major remaining scientific challenges that need to be overcome in order to bank organs, and identified key opportunities to accelerate progress toward this goal. Many areas of public health could be revolutionized by the banking of organs and other complex tissues, including transplantation, oncofertility, tissue engineering, trauma medicine and emergency preparedness, basic biomedical research and drug discovery - and even space travel. Key remaining scientific sub-challenges were discussed including ice nucleation and growth, cryoprotectant and osmotic toxicities, chilling injury, thermo-mechanical stress, the need for rapid and uniform rewarming, and ischemia/reperfusion injury. A variety of opportunities to overcome these challenge areas were discussed, i.e. preconditioning for enhanced stress tolerance, nanoparticle rewarming, cyroprotectant screening strategies, and the use of cryoprotectant cocktails including ice binding agents. Copyright © 2015.

  14. Lessons learned from participating in D3R 2016 Grand Challenge 2: compounds targeting the farnesoid X receptor

    Science.gov (United States)

    Duan, Rui; Xu, Xianjin; Zou, Xiaoqin

    2018-01-01

    D3R 2016 Grand Challenge 2 focused on predictions of binding modes and affinities for 102 compounds against the farnesoid X receptor (FXR). In this challenge, two distinct methods, a docking-based method and a template-based method, were employed by our team for the binding mode prediction. For the new template-based method, 3D ligand similarities were calculated for each query compound against the ligands in the co-crystal structures of FXR available in Protein Data Bank. The binding mode was predicted based on the co-crystal protein structure containing the ligand with the best ligand similarity score against the query compound. For the FXR dataset, the template-based method achieved a better performance than the docking-based method on the binding mode prediction. For the binding affinity prediction, an in-house knowledge-based scoring function ITScore2 and MM/PBSA approach were employed. Good performance was achieved for MM/PBSA, whereas the performance of ITScore2 was sensitive to ligand composition, e.g. the percentage of carbon atoms in the compounds. The sensitivity to ligand composition could be a clue for the further improvement of our knowledge-based scoring function.

  15. Physics and the canalization of morphogenesis: a grand challenge in organismal biology

    International Nuclear Information System (INIS)

    Von Dassow, Michelangelo; Davidson, Lance A

    2011-01-01

    Morphogenesis takes place against a background of organism-to-organism and environmental variation. Therefore, fundamental questions in the study of morphogenesis include: How are the mechanical processes of tissue movement and deformation affected by that variability, and in turn, how do the mechanic of the system modulate phenotypic variation? We highlight a few key factors, including environmental temperature, embryo size and environmental chemistry that might perturb the mechanics of morphogenesis in natural populations. Then we discuss several ways in which mechanics—including feedback from mechanical cues—might influence intra-specific variation in morphogenesis. To understand morphogenesis it will be necessary to consider whole-organism, environment and evolutionary scales because these larger scales present the challenges that developmental mechanisms have evolved to cope with. Studying the variation organisms express and the variation organisms experience will aid in deciphering the causes of birth defects

  16. Psychological science's contributions to a sustainable environment: extending our reach to a grand challenge of society.

    Science.gov (United States)

    Kazdin, Alan E

    2009-01-01

    Climate change and degradation of the environment are global problems associated with many other challenges (e.g., population increases, reduction of glaciers, and loss of critical habitats). Psychological science can play a critical role in addressing these problems by fostering a sustainable environment. Multiple strategies for fostering a sustainable environment could draw from the diversity of topics and areas of specialization within psychology. Psychological research on fostering environmentally sustainable behaviors is rather well developed, as illustrated by interventions focusing on education of the public, message framing, feedback, decision making, the media, incentives and disincentives, and social marketing. Other sciences and professions as well as religion and ethics are actively involved in fostering a sustainable environment. Psychology ought to be more involved directly, systematically, and visibly to draw on our current knowledge and to have palpable impact. We would serve the world very well and in the process our discipline and profession.

  17. Tipping Points and Balancing Acts: Grand Challenges and Synergistic Opportunities of Integrating Research and Education, Science and Solutions

    Science.gov (United States)

    McCaffrey, M. S.; Stroeve, J. C.

    2011-12-01

    The "Grand Challenges" to address Global Change identified by the International Council for Science (ICSU) and its partners through the Earth System Sustainability Initiative-improving forecasting, enhancing and integrating observation systems, confining and minimizing global environmental change, responding effectively to change, as well as innovating and evaluating these efforts-require an integrative approach that engages and inspires society in general and young people in particular. What are some of the effective strategies-and stumbling blocks-in being able to make Earth System science and related sustainability efforts relevant and practical to non-technical audiences? Recent climate education projects have pioneered new strategies toward linking and infusing research with education, science with solutions. For example, the Climate Literacy and Energy Awareness Network (CLEAN), a National Science Digital Library Pathway funded by NSF, has approached this integral approach by "closing the loop" between climate and energy topics, identifying and annotating high quality online resources relating to the carbon cycle and related topics. The Inspiring Climate Education Excellence (ICEE) project, funded by NASA, offers professional development for teachers that infuses climate science with solutions as an emerging "best practice" while being sensitive to the emotional, psychological and political aspects of avoiding "gloom and doom" on one hand or advocating for particular policy solutions on another. Other examples includes NASA's climate website (http://climate.nasa.gov ), which serves as a robust, engaging portal for climate research and data, especially for educators. The recent PBS series Earth: The Operators' Manual and related book and website are other recent example of how climate science research, education and solutions can be incorporated in a way that is appealing and informative. The Alliance for Climate Education (ACE) has given assemblies in

  18. CAWR: Two institutions join forces in a cluster by addressing the grand challenges of water research

    Science.gov (United States)

    Jaeckel, Greta; Braeckevelt, Mareike

    2017-04-01

    The Center for Advanced Water Research (CAWR) brings together the water competences of two German research institutions: Helmholtz Centre for Environmental Research - UFZ and the Technische Universität Dresden (TUD). Highly qualified scientists are jointly tackling some of the key challenges in the water sector in an outstanding breadth of research topics and at the same time with a profound disciplinary expertise. Our mission is: "Save water for humans and environment", because water in a good quality and adequate quantity is a fundamental basis of life for humankind and the environment. In many global challenges, such as food or energy security, human health and ecosystems, flood defence and droughts or the provision of drinking water and sanitation systems, water is becoming a very critical element for a sustainable society in Germany, in Europe and worldwide. The CAWR focusses its work on the fields of research, education & training as well as transfer. The CAWR was established in 2013. Over 3 years the activities within the three pillars and the six thematic priority research fields ( 1) Understanding processes: water cycle and water quality, 2): Water quantity and scarcity in the regional context, 3): Urban Water Systems, 4): Methods of data collection and information processing, 5): Societal and climate change, 6): Water governance) were presented within: • the scientific community (newsletters, publication highlights, workshops with different new formats, conferences) • to national and international stakeholders from policy, industry and society (workshops, opinion papers) • public media (TV, radio stations, Newspapers, brochures, videoclips via youtube…) This PICO presentation by Greta Jäckel (scientific management of CAWR) should show which tools for the presentation of research results are useful and which influence they have on different target groups. A bunch of examples for effective and also less successful instruments to present important

  19. The grand challenge of great ape health and conservation in the anthropocene.

    Science.gov (United States)

    Travis, Dominic A; Lonsorf, Elizabeth V; Gillespie, Thomas R

    2018-01-01

    "Ecosystem Health recognizes the inherent interdependence of the health of humans, animals and ecosystems and explores the perspectives, theories and methodologies emerging at the interface between ecological and health sciences." This broad focus requires new approaches and methods for solving problems of greater complexity at larger scales than ever before. Nowhere is this point more salient than the case of disease emergence and control at the human-non human primate interface in shrinking tropical forests under great anthropogenic pressure. This special edition brings together transdisciplinary experts who have created successful partnerships leading to advances in ecosystem approaches to health for wild ape populations with relevance to all developing country tropical forest environments. It is no coincidence that the advances herein highlight two long term health projects-the Gombe Ecosystem Health Project (Gombe National Park, Tanzania), and the Taï Chimpanzee Project (TCP) in Côte d'Ivoire-since standardizing and validating noninvasive disease surveillance, risk assessment and management methods presents a special series of challenges where time is a major factor. Advances highlighted in this addition include: health surveillance and monitoring, health risk analysis, field immobilization and interventions, human-NHP networks/interfaces, diagnostic tool development, and cutting edge molecular and genetic techniques. © 2017 Wiley Periodicals, Inc.

  20. Scientific Grand Challenges: Forefront Questions in Nuclear Science and the Role of High Performance Computing

    International Nuclear Information System (INIS)

    Khaleel, Mohammad A.

    2009-01-01

    This report is an account of the deliberations and conclusions of the workshop on 'Forefront Questions in Nuclear Science and the Role of High Performance Computing' held January 26-28, 2009, co-sponsored by the U.S. Department of Energy (DOE) Office of Nuclear Physics (ONP) and the DOE Office of Advanced Scientific Computing (ASCR). Representatives from the national and international nuclear physics communities, as well as from the high performance computing community, participated. The purpose of this workshop was to (1) identify forefront scientific challenges in nuclear physics and then determine which-if any-of these could be aided by high performance computing at the extreme scale; (2) establish how and why new high performance computing capabilities could address issues at the frontiers of nuclear science; (3) provide nuclear physicists the opportunity to influence the development of high performance computing; and (4) provide the nuclear physics community with plans for development of future high performance computing capability by DOE ASCR.

  1. Scientific Grand Challenges: Forefront Questions in Nuclear Science and the Role of High Performance Computing

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.

    2009-10-01

    This report is an account of the deliberations and conclusions of the workshop on "Forefront Questions in Nuclear Science and the Role of High Performance Computing" held January 26-28, 2009, co-sponsored by the U.S. Department of Energy (DOE) Office of Nuclear Physics (ONP) and the DOE Office of Advanced Scientific Computing (ASCR). Representatives from the national and international nuclear physics communities, as well as from the high performance computing community, participated. The purpose of this workshop was to 1) identify forefront scientific challenges in nuclear physics and then determine which-if any-of these could be aided by high performance computing at the extreme scale; 2) establish how and why new high performance computing capabilities could address issues at the frontiers of nuclear science; 3) provide nuclear physicists the opportunity to influence the development of high performance computing; and 4) provide the nuclear physics community with plans for development of future high performance computing capability by DOE ASCR.

  2. Large scale free energy calculations for blind predictions of protein-ligand binding: the D3R Grand Challenge 2015.

    Science.gov (United States)

    Deng, Nanjie; Flynn, William F; Xia, Junchao; Vijayan, R S K; Zhang, Baofeng; He, Peng; Mentes, Ahmet; Gallicchio, Emilio; Levy, Ronald M

    2016-09-01

    We describe binding free energy calculations in the D3R Grand Challenge 2015 for blind prediction of the binding affinities of 180 ligands to Hsp90. The present D3R challenge was built around experimental datasets involving Heat shock protein (Hsp) 90, an ATP-dependent molecular chaperone which is an important anticancer drug target. The Hsp90 ATP binding site is known to be a challenging target for accurate calculations of ligand binding affinities because of the ligand-dependent conformational changes in the binding site, the presence of ordered waters and the broad chemical diversity of ligands that can bind at this site. Our primary focus here is to distinguish binders from nonbinders. Large scale absolute binding free energy calculations that cover over 3000 protein-ligand complexes were performed using the BEDAM method starting from docked structures generated by Glide docking. Although the ligand dataset in this study resembles an intermediate to late stage lead optimization project while the BEDAM method is mainly developed for early stage virtual screening of hit molecules, the BEDAM binding free energy scoring has resulted in a moderate enrichment of ligand screening against this challenging drug target. Results show that, using a statistical mechanics based free energy method like BEDAM starting from docked poses offers better enrichment than classical docking scoring functions and rescoring methods like Prime MM-GBSA for the Hsp90 data set in this blind challenge. Importantly, among the three methods tested here, only the mean value of the BEDAM binding free energy scores is able to separate the large group of binders from the small group of nonbinders with a gap of 2.4 kcal/mol. None of the three methods that we have tested provided accurate ranking of the affinities of the 147 active compounds. We discuss the possible sources of errors in the binding free energy calculations. The study suggests that BEDAM can be used strategically to discriminate

  3. Communicating Geosciences with Policy-makers: a Grand Challenge for Academia

    Science.gov (United States)

    Harrison, W. J.; Walls, M. R.; Boland, M. A.

    2015-12-01

    Geoscientists interested in the broader societal impacts of their research can make a meaningful contribution to policy making in our changing world. Nevertheless, policy and public decision making are the least frequently cited Broader Impacts in proposals and funded projects within NSF's Geosciences Directorate. Academic institutions can play a lead role by introducing this societal dimension of our profession to beginning students, and by enabling interdisciplinary research and promoting communication pathways for experienced career geoscientists. Within the academic environment, the public interface of the geosciences can be presented through curriculum content and creative programs. These include undergraduate minors in economics or public policy designed for scientists and engineers, and internships with policy makers. Federal research institutions and other organizations provide valuable policy-relevant experiences for students. Academic institutions have the key freedom of mission to tackle interdisciplinary research challenges at the interface of geoscience and policy. They develop long-standing relationships with research partners, including national laboratories and state geological surveys, whose work may support policy development and analysis at local, state, regional, and national levels. CSM's Payne Institute for Earth Resources awards mini-grants for teams of researchers to develop collaborative research efforts between engineering/science and policy researchers. Current work in the areas of nuclear generation and the costs of climate policy and on policy alternatives for capturing fugitive methane emissions are examples of work at the interface between the geosciences and public policy. With academic engagement, geoscientists can steward their intellectual output when non-scientists translate geoscience information and concepts into action through public policies.

  4. AI in medical education--another grand challenge for medical informatics.

    Science.gov (United States)

    Lillehaug, S I; Lajoie, S P

    1998-03-01

    The potential benefits of artificial intelligence in medicine (AIM) were never realized as anticipated. This paper addresses ways in which such potential can be achieved. Recent discussions of this topic have proposed a stronger integration between AIM applications and health information systems, and emphasize computer guidelines to support the new health care paradigms of evidence-based medicine and cost-effectiveness. These proposals, however, promote the initial definition of AIM applications as being AI systems that can perform or aid in diagnoses. We challenge this traditional philosophy of AIM and propose a new approach aiming at empowering health care workers to become independent self-sufficient problem solvers and decision makers. Our philosophy is based on findings from a review of empirical research that examines the relationship between the health care personnel's level of knowledge and skills, their job satisfaction, and the quality of the health care they provide. This review supports addressing the quality of health care by empowering health care workers to reach their full potential. As an aid in this empowerment process we argue for reviving a long forgotten AIM research area, namely, AI based applications for medical education and training. There is a growing body of research in artificial intelligence in education that demonstrates that the use of artificial intelligence can enhance learning in numerous domains. By examining the strengths of these educational applications and the results from previous AIM research we derive a framework for empowering medical personnel and consequently raising the quality of health care through the use of advanced AI based technology.

  5. Next-Generation Photon Sources for Grand Challenges in Science and Energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-05-01

    report identifies two aspects of energy science in which next-generation ultraviolet and X-ray light sources will have the deepest and broadest impact: (1) The temporal evolution of electrons, spins, atoms, and chemical reactions, down to the femtosecond time scale. (2) Spectroscopic and structural imaging of nano objects (or nanoscale regions of inhomogeneous materials) with nanometer spatial resolution and ultimate spectral resolution. The dual advances of temporal and spatial resolution promised by fourth-generation light sources ideally match the challenges of control science. Femtosecond time resolution has opened completely new territory where atomic motion can be followed in real time and electronic excitations and decay processes can be followed over time. Coherent imaging with short-wavelength radiation will make it possible to access the nanometer length scale, where intrinsic quantum behavior becomes dominant. Performing spectroscopy on individual nanometer-scale objects rather than on conglomerates will eliminate the blurring of the energy levels induced by particle size and shape distributions and reveal the energetics of single functional units. Energy resolution limited only by the uncertainty relation is enabled by these advances. Current storage-ring-based light sources and their incremental enhancements cannot meet the need for femtosecond time resolution, nanometer spatial resolution, intrinsic energy resolution, full coherence over energy ranges up to hard X-rays, and peak brilliance required to enable the new science outlined in this report. In fact, the new, unexplored territory is so expansive that no single currently imagined light source technology can fulfill the whole potential. Both technological and economic challenges require resolution as we move forward. For example, femtosecond time resolution and high peak brilliance are required for following chemical reactions in real time, but lower peak brilliance and high repetition rate are needed

  6. Grand challenges in developing a predictive understanding of global fire dynamics

    Science.gov (United States)

    Randerson, J. T.; Chen, Y.; Wiggins, E. B.; Andela, N.; Morton, D. C.; Veraverbeke, S.; van der Werf, G.

    2017-12-01

    High quality satellite observations of burned area and fire thermal anomalies over the past two decades have transformed our understanding of climate, ecosystem, and human controls on the spatial and temporal distribution of landscape fires. The satellite observations provide evidence for a rapid and widespread loss of fire from grassland and savanna ecosystems worldwide. Continued expansion of industrial agriculture suggests that observed declines in global burned area are likely to continue in future decades, with profound consequences for ecosystem function and the habitat of many endangered species. Satellite time series also highlight the importance of El Niño-Southern Oscillation and other climate modes as drivers of interannual variability. In many regions, lead times between climate indices and fire activity are considerable, enabling the development of early warning prediction systems for fire season severity. With the recent availability of high-resolution observations from Suomi NPP, Landsat 8, and Sentinel 2, the field of global fire ecology is poised to make even more significant breakthroughs over the next decade. With these new observations, it may be possible to reduce uncertainties in the spatial pattern of burned area by several fold. It is difficult to overstate the importance of these new data constraints for improving our understanding of fire impacts on human health and radiative forcing of climate change. A key research challenge in this context is to understand how the loss of global burned area will affect magnitude of the terrestrial carbon sink and trends in atmospheric composition. Advances in prognostic fire modeling will require new approaches linking agriculture with landscape fire dynamics. A critical need in this context is the development of predictive models of road networks and other drivers of land fragmentation, and a closer integration of fragmentation information with algorithms predicting fire spread. Concurrently, a better

  7. Overview of implementation of DARPA GPU program in SAIC

    Science.gov (United States)

    Braunreiter, Dennis; Furtek, Jeremy; Chen, Hai-Wen; Healy, Dennis

    2008-04-01

    This paper reviews the implementation of DARPA MTO STAP-BOY program for both Phase I and II conducted at Science Applications International Corporation (SAIC). The STAP-BOY program conducts fast covariance factorization and tuning techniques for space-time adaptive process (STAP) Algorithm Implementation on Graphics Processor unit (GPU) Architectures for Embedded Systems. The first part of our presentation on the DARPA STAP-BOY program will focus on GPU implementation and algorithm innovations for a prototype radar STAP algorithm. The STAP algorithm will be implemented on the GPU, using stream programming (from companies such as PeakStream, ATI Technologies' CTM, and NVIDIA) and traditional graphics APIs. This algorithm will include fast range adaptive STAP weight updates and beamforming applications, each of which has been modified to exploit the parallel nature of graphics architectures.

  8. Combining Multidisciplinary Science, Quantitative Reasoning and Social Context to Teach Global Sustainability and Prepare Students for 21st Grand Challenges

    Science.gov (United States)

    Myers, J. D.

    2011-12-01

    The Earth's seven billion humans are consuming a growing proportion of the world's ecosystem products and services. Human activity has also wrought changes that rival the scale of many natural geologic processes, e.g. erosion, transport and deposition, leading to recognition of a new geological epoch, the Anthropocene. Because of these impacts, several natural systems have been pushed beyond the planetary boundaries that made the Holocene favorable for the expansion of humanity. Given these human-induced stresses on natural systems, global citizens will face an increasing number of grand challenges. Unfortunately, traditional discipline-based introductory science courses do little to prepare students for these complex, scientifically-based and technologically-centered challenges. With NSF funding, an introductory, integrated science course stressing quantitative reasoning and social context has been created at UW. The course (GEOL1600: Global Sustainability: Managing the Earth's Resources) is a lower division course designed around the energy-water-climate (EWC) nexus and integrating biology, chemistry, Earth science and physics. It melds lectures, lecture activities, reading questionnaires and labs to create a learning environment that examines the EWT nexus from a global through regional context. The focus on the EWC nexus, while important socially and intended to motivate students, also provides a coherent framework for identifying which disciplinary scientific principles and concepts to include in the course: photosynthesis and deep time (fossil fuels), biogeochemical cycles (climate), chemical reactions (combustion), electromagnetic radiation (solar power), nuclear physics (nuclear power), phase changes and diagrams (water and climate), etc. Lecture activities are used to give students the practice they need to make quantitative skills routine and automatic. Laboratory exercises on energy (coal, petroleum, nuclear power), water (in Bangladesh), energy

  9. Grand Challenge Problem 10

    DEFF Research Database (Denmark)

    Dirckinck-Holmfeld, Lone; Balacheff, Nicolas; Bottino, Rosa Maria

    2016-01-01

    Small and medium sized research labs (SMLs) are dominating European TEL research. This is justified by the great numbers of countries and regions in Europe needing to develop a research and innovation competence to facilitate the diverse educational systems contextualized in various institutional...

  10. Developing a Speaker Identification System for the DARPA RATS Project

    DEFF Research Database (Denmark)

    Plchot, O; Matsoukas, S; Matejka, P

    2013-01-01

    This paper describes the speaker identification (SID) system developed by the Patrol team for the first phase of the DARPA RATS (Robust Automatic Transcription of Speech) program, which seeks to advance state of the art detection capabilities on audio from highly degraded communication channels. ...... such as CFCCs out-perform MFCC front-ends on noisy audio, and (c) fusion of multiple systems provides 24% relative improvement in EER compared to the single best system when using a novel SVM-based fusion algorithm that uses side information such as gender, language, and channel id....

  11. 77 FR 44063 - Federal Acquisition Regulations; DARPA-New Mexico Tax Agreement

    Science.gov (United States)

    2012-07-26

    ... Federal Acquisition Regulation (FAR) to add the United States Defense Advanced Research Projects Agency... Mexico (NM). The DARPA-NM tax agreement eliminates the double taxation of Government cost-reimbursement... 2012- 019. SUPPLEMENTARY INFORMATION: I. Background On August 18, 2011, DARPA and the Taxation and...

  12. Predicting the affinity of Farnesoid X Receptor ligands through a hierarchical ranking protocol: a D3R Grand Challenge 2 case study

    Science.gov (United States)

    Réau, Manon; Langenfeld, Florent; Zagury, Jean-François; Montes, Matthieu

    2018-01-01

    The Drug Design Data Resource (D3R) Grand Challenges are blind contests organized to assess the state-of-the-art methods accuracy in predicting binding modes and relative binding free energies of experimentally validated ligands for a given target. The second stage of the D3R Grand Challenge 2 (GC2) was focused on ranking 102 compounds according to their predicted affinity for Farnesoid X Receptor. In this task, our workflow was ranked 5th out of the 77 submissions in the structure-based category. Our strategy consisted in (1) a combination of molecular docking using AutoDock 4.2 and manual edition of available structures for binding poses generation using SeeSAR, (2) the use of HYDE scoring for pose selection, and (3) a hierarchical ranking using HYDE and MM/GBSA. In this report, we detail our pose generation and ligands ranking protocols and provide guidelines to be used in a prospective computer aided drug design program.

  13. The use of the Climate-science Computational End Station (CCES) development and grand challenge team for the next IPCC assessment: an operational plan

    International Nuclear Information System (INIS)

    Washington, W M; Buja, L; Gent, P; Drake, J; Erickson, D; Anderson, D; Bader, D; Dickinson, R; Ghan, S; Jones, P; Jacob, R

    2008-01-01

    The grand challenge of climate change science is to predict future climates based on scenarios of anthropogenic emissions and other changes resulting from options in energy and development policies. Addressing this challenge requires a Climate Science Computational End Station consisting of a sustained climate model research, development, and application program combined with world-class DOE leadership computing resources to enable advanced computational simulation of the Earth system. This project provides the primary computer allocations for the DOE SciDAC and Climate Change Prediction Program. It builds on the successful interagency collaboration of the National Science and the U.S. Department of Energy in developing and applying the Community Climate System Model (CCSM) for climate change science. It also includes collaboration with the National Aeronautics and Space Administration in carbon data assimilation and university partners with expertise in high-end computational climate research

  14. Long-term Water Table Monitoring of Rio Grande Riparian Ecosystems for Restoration Potential Amid Hydroclimatic Challenges

    Science.gov (United States)

    Thibault, James R.; Cleverly, James R.; Dahm, Clifford N.

    2017-12-01

    Hydrological processes drive the ecological functioning and sustainability of cottonwood-dominated riparian ecosystems in the arid southwestern USA. Snowmelt runoff elevates groundwater levels and inundates floodplains, which promotes cottonwood germination. Once established, these phreatophytes rely on accessible water tables (WTs). In New Mexico's Middle Rio Grande corridor diminished flooding and deepening WTs threaten native riparian communities. We monitored surface flows and riparian WTs for up to 14 years, which revealed that WTs and surface flows, including peak snowmelt discharge, respond to basin climate conditions and resource management. WT hydrographs influence the composition of riparian communities and can be used to assess if potential restoration sites meet native vegetation tolerances for WT depths, rates of recession, and variability throughout their life stages. WTs were highly variable in some sites, which can preclude native vegetation less adapted to deep drawdowns during extended droughts. Rates of WT recession varied between sites and should be assessed in regard to recruitment potential. Locations with relatively shallow WTs and limited variability are likely to be more viable for successful restoration. Suitable sites have diminished greatly as the once meandering Rio Grande has been constrained and depleted. Increasing demands on water and the presence of invasive vegetation better adapted to the altered hydrologic regime further impact native riparian communities. Long-term monitoring over a range of sites and hydroclimatic extremes reveals attributes that can be evaluated for restoration potential.

  15. Steady and Unsteady Force and Moment Data on a DARPA2 Submarine

    OpenAIRE

    Whitfield, Cindy Carol

    1999-01-01

    Steady and unsteady force and moment experiments were conducted in the Virginia Tech Stability wind tunnel using the Dynamic Plunge-Pitch-Roll (DyPPiR) model mount to perform rapid time-dependent,high-excursion maneuvers. The experiments were performed for a DARPA2 submarine model using three widely spaced 2-force-component loadcells and three tri-axial accelerometers to extract the aerodynamic loads. The DARPA2 model was tested with different body configurations in two different test sect...

  16. Exploration of Digital Circuits and Transistor-Level Testing in the DARPA TRUST Program

    Science.gov (United States)

    2015-03-01

    attacked is to have the Trojan Horse being the signal. The term Trojan Horse was originally invented when the Greek soldiers tried to invade Troy but...night Greek soldiers came out of the horse and destroyed the city. Nowadays, a Trojan Horse is a seemingly innocuous piece of hardware or software...the DARPA TRUST program was initiated and continues to be a vital component in the war fighting effort of the DoD. One reason that the DARPA TRUST

  17. The DARPA compact Superconducting X-Ray Lithography Source features

    International Nuclear Information System (INIS)

    Heese, R.; Kalsi, S.; Leung, E.

    1991-01-01

    Under DARPA sponsorship, a compact Superconducting X-Ray Lithography Source (SXLS) is being designed and built by the Brookhaven National Laboratory (BNL) with industry participation from Grumman Corporation and General Dynamics. This source is optimized for lithography work for sub-micron high density computer chips, and is about the size of a billiard table (1.5 m x 4.0 m). The machine has a racetrack configuration with two 180 degree bending magnets being designed and built by General Dynamics under a subcontract with Grumman Corporation. The machine will have 18 photon ports which would deliver light peaked at a wave length of 10 Angstroms. Grumman is commercializing the SXLS device and plans to book orders for delivery of industrialized SXLS (ISXLS) versions in 1995. This paper will describe the major features of this device. The commercial machine will be equipped with a fully automated user-friendly control systems, major features of which are already working on a compact warm dipole ring at BNL. This ring has normal dipole magnets with dimensions identical to the SXLS device, and has been successfully commissioned

  18. Workflows and performances in the ranking prediction of 2016 D3R Grand Challenge 2: lessons learned from a collaborative effort.

    Science.gov (United States)

    Gao, Ying-Duo; Hu, Yuan; Crespo, Alejandro; Wang, Deping; Armacost, Kira A; Fells, James I; Fradera, Xavier; Wang, Hongwu; Wang, Huijun; Sherborne, Brad; Verras, Andreas; Peng, Zhengwei

    2018-01-01

    The 2016 D3R Grand Challenge 2 includes both pose and affinity or ranking predictions. This article is focused exclusively on affinity predictions submitted to the D3R challenge from a collaborative effort of the modeling and informatics group. Our submissions include ranking of 102 ligands covering 4 different chemotypes against the FXR ligand binding domain structure, and the relative binding affinity predictions of the two designated free energy subsets of 15 and 18 compounds. Using all the complex structures prepared in the same way allowed us to cover many types of workflows and compare their performances effectively. We evaluated typical workflows used in our daily structure-based design modeling support, which include docking scores, force field-based scores, QM/MM, MMGBSA, MD-MMGBSA, and MacroModel interaction energy estimations. The best performing methods for the two free energy subsets are discussed. Our results suggest that affinity ranking still remains very challenging; that the knowledge of more structural information does not necessarily yield more accurate predictions; and that visual inspection and human intervention are considerably important for ranking. Knowledge of the mode of action and protein flexibility along with visualization tools that depict polar and hydrophobic maps are very useful for visual inspection. QM/MM-based workflows were found to be powerful in affinity ranking and are encouraged to be applied more often. The standardized input and output enable systematic analysis and support methodology development and improvement for high level blinded predictions.

  19. Workflows and performances in the ranking prediction of 2016 D3R Grand Challenge 2: lessons learned from a collaborative effort

    Science.gov (United States)

    Gao, Ying-Duo; Hu, Yuan; Crespo, Alejandro; Wang, Deping; Armacost, Kira A.; Fells, James I.; Fradera, Xavier; Wang, Hongwu; Wang, Huijun; Sherborne, Brad; Verras, Andreas; Peng, Zhengwei

    2018-01-01

    The 2016 D3R Grand Challenge 2 includes both pose and affinity or ranking predictions. This article is focused exclusively on affinity predictions submitted to the D3R challenge from a collaborative effort of the modeling and informatics group. Our submissions include ranking of 102 ligands covering 4 different chemotypes against the FXR ligand binding domain structure, and the relative binding affinity predictions of the two designated free energy subsets of 15 and 18 compounds. Using all the complex structures prepared in the same way allowed us to cover many types of workflows and compare their performances effectively. We evaluated typical workflows used in our daily structure-based design modeling support, which include docking scores, force field-based scores, QM/MM, MMGBSA, MD-MMGBSA, and MacroModel interaction energy estimations. The best performing methods for the two free energy subsets are discussed. Our results suggest that affinity ranking still remains very challenging; that the knowledge of more structural information does not necessarily yield more accurate predictions; and that visual inspection and human intervention are considerably important for ranking. Knowledge of the mode of action and protein flexibility along with visualization tools that depict polar and hydrophobic maps are very useful for visual inspection. QM/MM-based workflows were found to be powerful in affinity ranking and are encouraged to be applied more often. The standardized input and output enable systematic analysis and support methodology development and improvement for high level blinded predictions.

  20. Combining self- and cross-docking as benchmark tools: the performance of DockBench in the D3R Grand Challenge 2

    Science.gov (United States)

    Salmaso, Veronica; Sturlese, Mattia; Cuzzolin, Alberto; Moro, Stefano

    2018-01-01

    Molecular docking is a powerful tool in the field of computer-aided molecular design. In particular, it is the technique of choice for the prediction of a ligand pose within its target binding site. A multitude of docking methods is available nowadays, whose performance may vary depending on the data set. Therefore, some non-trivial choices should be made before starting a docking simulation. In the same framework, the selection of the target structure to use could be challenging, since the number of available experimental structures is increasing. Both issues have been explored within this work. The pose prediction of a pool of 36 compounds provided by D3R Grand Challenge 2 organizers was preceded by a pipeline to choose the best protein/docking-method couple for each blind ligand. An integrated benchmark approach including ligand shape comparison and cross-docking evaluations was implemented inside our DockBench software. The results are encouraging and show that bringing attention to the choice of the docking simulation fundamental components improves the results of the binding mode predictions.

  1. Grandes remolques

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1961-07-01

    Full Text Available El empleo creciente del material pesado auxiliar en la construcción de obras de ingeniería civil ha motivado la fabricación de grandes plataformas, capaces de transportar toda clase de maquinaria auxiliar. En general, este tipo de maquinaria requiere medios de transporte, pues su circulación por carreteras es lenta, obstructiva y cara, siempre que se trate de grandes distancias, caso presente en la mayoría de ocasiones en que se exige un traslado de esta maquinaria de una a otra obra.

  2. Semantic Web Services with Web Ontology Language (OWL-S) - Specification of Agent-Services for DARPA Agent Markup Language (DAML)

    National Research Council Canada - National Science Library

    Sycara, Katia P

    2006-01-01

    CMU did research and development on semantic web services using OWL-S, the semantic web service language under the Defense Advanced Research Projects Agency- DARPA Agent Markup Language (DARPA-DAML) program...

  3. Key Concepts for and Assessment of an Undergraduate Class that Engages Engineering Students in Climate Change Grand Challenge

    Science.gov (United States)

    Powers, S. E.; DeWaters, J.; Dhaniyala, S.

    2015-12-01

    Engineers must take a leading role in addressing the challenges of mitigating climate change and adapting to the inevitable changes that our world is facing. Yet climate change classes targeting engineering students are scarce. Technical education must focus on the problem formulation and solutions that consider multiple, complex interactions between engineered systems and the Earth's climate system and recognize that transformation raises societal challenges, including trade-offs among benefits, costs, and risks. Moreover, improving engineering students' climate science literacy will require strategies that also inspire students' motivation to work toward their solution. A climate science course for engineers has been taught 5 semesters as part of a NASA Innovations in Climate Education program grant (NNXlOAB57A). The basic premise of this project was that effective instruction must incorporate scientifically-based knowledge and observations and foster critical thinking, problem solving, and decision-making skills. Lecture, in-class cooperative and computer-based learning and a semester project provide the basis for engaging students in evaluating effective mitigation and adaptation solutions. Policy and social issues are integrated throughout many of the units. The objective of this presentation is to highlight the content and pedagogical approach used in this class that helped to contribute to significant gains in engineering students' climate literacy and critical thinking competencies. A total of 89 students fully participated in a pre/post climate literacy questionnaire. As a whole, students demonstrated significant gains in climate-related content knowledge (pproblem statements and solutions in a manner that incorporated a multidimensional systems perspective. These skills are sometimes foreign to technically focused, number crunching engineering students, but are critical for using their engineering skills and profession to address climate change mitigation

  4. 77 FR 66823 - Freedom of Information Act Request for Papers Submitted to DARPA for the 2011 100 Year Starship...

    Science.gov (United States)

    2012-11-07

    ... DEPARTMENT OF DEFENSE Office of the Secretary Freedom of Information Act Request for Papers... by DARPA under the Freedom of Information Act. DATES: All written correspondence must be received by DARPA by close of business December 7, 2012. ADDRESSES: Send written comments concerning this Freedom of...

  5. Software Engineering Support of the Third Round of Scientific Grand Challenge Investigations: Earth System Modeling Software Framework Survey

    Science.gov (United States)

    Talbot, Bryan; Zhou, Shu-Jia; Higgins, Glenn; Zukor, Dorothy (Technical Monitor)

    2002-01-01

    One of the most significant challenges in large-scale climate modeling, as well as in high-performance computing in other scientific fields, is that of effectively integrating many software models from multiple contributors. A software framework facilitates the integration task, both in the development and runtime stages of the simulation. Effective software frameworks reduce the programming burden for the investigators, freeing them to focus more on the science and less on the parallel communication implementation. while maintaining high performance across numerous supercomputer and workstation architectures. This document surveys numerous software frameworks for potential use in Earth science modeling. Several frameworks are evaluated in depth, including Parallel Object-Oriented Methods and Applications (POOMA), Cactus (from (he relativistic physics community), Overture, Goddard Earth Modeling System (GEMS), the National Center for Atmospheric Research Flux Coupler, and UCLA/UCB Distributed Data Broker (DDB). Frameworks evaluated in less detail include ROOT, Parallel Application Workspace (PAWS), and Advanced Large-Scale Integrated Computational Environment (ALICE). A host of other frameworks and related tools are referenced in this context. The frameworks are evaluated individually and also compared with each other.

  6. Responses to Environmental & Societal Challenges for our Unstable Earth (RESCUE) foresight initiative - towards a European response to grand challenges in sustainability research and learning

    Science.gov (United States)

    Avril, B.; et al.

    2012-04-01

    The "Responses to Environmental and Societal Challenges for our Unstable Earth" (RESCUE; www.esf.org/rescue) foresight initiative - a joint COST-ESF "Frontiers of Science" initiative - aimed to help Europe address the societal and scientific challenges related to global environmental change and the related resilience issues. In RESCUE, the focus of attention was on people and the goal was to stimulate an integrated, innovative response from natural, social and human sciences. The RESCUE foresight initiative began in September 2009 and has recently been completed. RESCUE had the following key objectives: 1. To propose a strategic process for natural, social and human sciences to improve their ability and capacity to work together to address global environmental change through interdisciplinary synergy and to respond effectively to societal and policy-relevant needs; 2. To articulate new scientific issues related to global environmental change and the related resilience issues, especially those of transdisciplinary nature and of major relevance to society; 3. To explore new approaches towards truly integrated, interdisciplinary science, and to facilitate the 'revolution' in education and capacity building it requires. The work of RESCUE focused on the following themes: · Contributions from social sciences and humanities in developing responses to challenges of the Anthropocene; · Collaboration between the natural, social and human sciences in global environmental change and resilience studies; · Requirements for research methodologies and data; · Education and capacity building - towards a 'revolution'; · The interface between science and policy, communication and outreach. The RESCUE recommendations include the following issues to be addressed by science-funders, science policy-makers, researchers, practitioners, educators and a range of other societal actors: · develop an institutional framework for an open knowledge society, · re-organise research so

  7. Meeting the Grand Challenge of Protecting Astronauts Health: Electrostatic Active Space Radiation Shielding for Deep Space Missions

    Science.gov (United States)

    Tripathi, Ram K.

    2016-01-01

    membrane structure (EIMS) in both charged and uncharged configurations. The amount of charge shielding behind and around the EIMS was studied for different combinations of membrane structure voltages and electron energies. Both passive and active shielding were observed, with active shielding capable of deflecting nearly all incoming electrons. The pattern of charge distribution around the structure was studied as well as the stability of the structures in the charge flow. The charge deflection experiments illustrate that the EIMS remain inflated during charge deflection, but will experience small amplitude oscillations. Investigations were performed to determine a potential cause of the vibrations. It is postulated these vibrations are due to the charge flux causing local membrane charge distribution changes. As the membrane structure inflation pressure is changed, the shape responds, and causes the observed sustained vibration. Having identified this phenomenon is important when considering electrostatically inflated membrane structures (EIMS) in a space environment. Additionally, this project included a study of membrane material impacts, specifically the impact of membrane thickness. Extremely thin materials presented new challenges with vacuum preparation techniques and rapid charging. The thinner and lighter membrane materials were successfully inflated using electrostatic forces in a vacuum chamber. However, care must be taken when varying the potentials of such lighter structures as the currents can cause local heating and melting of the very thin membranes. Lastly, a preliminary analysis is performed to study rough order of magnitude power requirements for using EIMS for radiation shielding. The EIMS power requirement becomes increasingly more challenging as the spacecraft voltage is increased. As a result, the emphasis is on the deflection of charges away from the spacecraft rather than totally stopping them. This significantly alleviates the initial power

  8. The Numerical Tokamak Project (NTP) simulation of turbulent transport in the core plasma: A grand challenge in plasma physics

    International Nuclear Information System (INIS)

    1993-12-01

    The long-range goal of the Numerical Tokamak Project (NTP) is the reliable prediction of tokamak performance using physics-based numerical tools describing tokamak physics. The NTP is accomplishing the development of the most advanced particle and extended fluid model's on massively parallel processing (MPP) environments as part of a multi-institutional, multi-disciplinary numerical study of tokamak core fluctuations. The NTP is a continuing focus of the Office of Fusion Energy's theory and computation program. Near-term HPCC work concentrates on developing a predictive numerical description of the core plasma transport in tokamaks driven by low-frequency collective fluctuations. This work addresses one of the greatest intellectual challenges to our understanding of the physics of tokamak performance and needs the most advanced computational resources to progress. We are conducting detailed comparisons of kinetic and fluid numerical models of tokamak turbulence. These comparisons are stimulating the improvement of each and the development of hybrid models which embody aspects of both. The combination of emerging massively parallel processing hardware and algorithmic improvements will result in an estimated 10**2--10**6 performance increase. Development of information processing and visualization tools is accelerating our comparison of computational models to one another, to experimental data, and to analytical theory, providing a bootstrap effect in our understanding of the target physics. The measure of success is the degree to which the experimentally observed scaling of fluctuation-driven transport may be predicted numerically. The NTP is advancing the HPCC Initiative through its state-of-the-art computational work. We are pushing the capability of high performance computing through our efforts which are strongly leveraged by OFE support

  9. Binding affinities of the farnesoid X receptor in the D3R Grand Challenge 2 estimated by free-energy perturbation and docking

    Science.gov (United States)

    Olsson, Martin A.; García-Sosa, Alfonso T.; Ryde, Ulf

    2018-01-01

    We have studied the binding of 102 ligands to the farnesoid X receptor within the D3R Grand Challenge 2016 blind-prediction competition. First, we employed docking with five different docking software and scoring functions. The selected docked poses gave an average root-mean-squared deviation of 4.2 Å. Consensus scoring gave decent results with a Kendall's τ of 0.26 ± 0.06 and a Spearman's ρ of 0.41 ± 0.08. For a subset of 33 ligands, we calculated relative binding free energies with free-energy perturbation. Five transformations between the ligands involved a change of the net charge and we implemented and benchmarked a semi-analytic correction (Rocklin et al., J Chem Phys 139:184103, 2013) for artifacts caused by the periodic boundary conditions and Ewald summation. The results gave a mean absolute deviation of 7.5 kJ/mol compared to the experimental estimates and a correlation coefficient of R 2 = 0.1. These results were among the four best in this competition out of 22 submissions. The charge corrections were significant (7-8 kJ/mol) and always improved the results. By employing 23 intermediate states in the free-energy perturbation, there was a proper overlap between all states and the precision was 0.1-0.7 kJ/mol. However, thermodynamic cycles indicate that the sampling was insufficient in some of the perturbations.

  10. Improving binding mode and binding affinity predictions of docking by ligand-based search of protein conformations: evaluation in D3R grand challenge 2015

    Science.gov (United States)

    Xu, Xianjin; Yan, Chengfei; Zou, Xiaoqin

    2017-08-01

    The growing number of protein-ligand complex structures, particularly the structures of proteins co-bound with different ligands, in the Protein Data Bank helps us tackle two major challenges in molecular docking studies: the protein flexibility and the scoring function. Here, we introduced a systematic strategy by using the information embedded in the known protein-ligand complex structures to improve both binding mode and binding affinity predictions. Specifically, a ligand similarity calculation method was employed to search a receptor structure with a bound ligand sharing high similarity with the query ligand for the docking use. The strategy was applied to the two datasets (HSP90 and MAP4K4) in recent D3R Grand Challenge 2015. In addition, for the HSP90 dataset, a system-specific scoring function (ITScore2_hsp90) was generated by recalibrating our statistical potential-based scoring function (ITScore2) using the known protein-ligand complex structures and the statistical mechanics-based iterative method. For the HSP90 dataset, better performances were achieved for both binding mode and binding affinity predictions comparing with the original ITScore2 and with ensemble docking. For the MAP4K4 dataset, although there were only eight known protein-ligand complex structures, our docking strategy achieved a comparable performance with ensemble docking. Our method for receptor conformational selection and iterative method for the development of system-specific statistical potential-based scoring functions can be easily applied to other protein targets that have a number of protein-ligand complex structures available to improve predictions on binding.

  11. Predicting binding poses and affinities for protein - ligand complexes in the 2015 D3R Grand Challenge using a physical model with a statistical parameter estimation

    Science.gov (United States)

    Grudinin, Sergei; Kadukova, Maria; Eisenbarth, Andreas; Marillet, Simon; Cazals, Frédéric

    2016-09-01

    The 2015 D3R Grand Challenge provided an opportunity to test our new model for the binding free energy of small molecules, as well as to assess our protocol to predict binding poses for protein-ligand complexes. Our pose predictions were ranked 3-9 for the HSP90 dataset, depending on the assessment metric. For the MAP4K dataset the ranks are very dispersed and equal to 2-35, depending on the assessment metric, which does not provide any insight into the accuracy of the method. The main success of our pose prediction protocol was the re-scoring stage using the recently developed Convex-PL potential. We make a thorough analysis of our docking predictions made with AutoDock Vina and discuss the effect of the choice of rigid receptor templates, the number of flexible residues in the binding pocket, the binding pocket size, and the benefits of re-scoring. However, the main challenge was to predict experimentally determined binding affinities for two blind test sets. Our affinity prediction model consisted of two terms, a pairwise-additive enthalpy, and a non pairwise-additive entropy. We trained the free parameters of the model with a regularized regression using affinity and structural data from the PDBBind database. Our model performed very well on the training set, however, failed on the two test sets. We explain the drawback and pitfalls of our model, in particular in terms of relative coverage of the test set by the training set and missed dynamical properties from crystal structures, and discuss different routes to improve it.

  12. Grandes cocinas

    Directory of Open Access Journals (Sweden)

    García de Castro, Emilio

    1957-11-01

    Full Text Available Se describen en este artículo una serie de aparatos para grandes cocinas, vistos por los autores durante un rápido viaje por Alemania. Aprovechando los datos obtenidos se analizan brevemente las necesidades de una gran cocina moderna, comentando los planos de las instalaciones en varios hoteles o instituciones de todo el mundo. La mayoría de la información.

  13. Big Data and Grand Challenges

    DEFF Research Database (Denmark)

    Finnemann, Niels Ole

    2016-01-01

    The paper discusses the future of the Humanities and the role of Digital Humanities. Taking the point of departure in Rens Bods “A new History of the humanities” (2013) it is argued that the current crisis within the Humanities and Digital Humanities is not as much about different notions of cult...

  14. Grand challenges for crop science

    Science.gov (United States)

    Crop science is a highly integrative science using the disciplines of conventional plant breeding, transgenic crop improvement, plant physiology, and cropping system sciences to develop improved varieties of agronomic, turf, and forage crops to produce feed, food, fuel, and fiber for our world's gro...

  15. Leveraging this Golden Age of Remote Sensing and Modeling of Terrestrial Hydrology to Understand Water Cycling in the Water Availability Grand Challenge for North America

    Science.gov (United States)

    Painter, T. H.; Famiglietti, J. S.; Stephens, G. L.

    2016-12-01

    We live in a time of increasing strains on our global fresh water availability due to increasing population, warming climate, changes in precipitation, and extensive depletion of groundwater supplies. At the same time, we have seen enormous growth in capabilities to remotely sense the regional to global water cycle and model complex systems with physically based frameworks. The GEWEX Water Availability Grand Challenge for North America is poised to leverage this convergence of remote sensing and modeling capabilities to answer fundamental questions on the water cycle. In particular, we envision an experiment that targets the complex and resource-critical Western US from California to just into the Great Plains, constraining physically-based hydrologic modeling with the US and international remote sensing capabilities. In particular, the last decade has seen the implementation or soon-to-be launch of water cycle missions such as GRACE and GRACE-FO for groundwater, SMAP for soil moisture, GPM for precipitation, SWOT for terrestrial surface water, and the Airborne Snow Observatory for snowpack. With the advent of convection-resolving mesoscale climate and water cycle modeling (e.g. WRF, WRF-Hydro) and mesoscale models capable of quantitative assimilation of remotely sensed data (e.g. the JPL Western States Water Mission), we can now begin to test hypotheses on the nature and changes in the water cycle of the Western US from a physical standpoint. In turn, by fusing water cycle science, water management, and ecosystem management while addressing these hypotheses, this golden age of remote sensing and modeling can bring all fields into a markedly less uncertain state of present knowledge and decadal scale forecasts.

  16. Handbook of natural language processing and machine translation DARPA global autonomous language exploitation

    CERN Document Server

    Olive, Joseph P; McCary, John

    2011-01-01

    This comprehensive handbook, written by leading experts in the field, details the groundbreaking research conducted under the breakthrough GALE program - The Global Autonomous Language Exploitation within the Defense Advanced Research Projects Agency (DARPA), while placing it in the context of previous research in the fields of natural language and signal processing, artificial intelligence and machine translation. The most fundamental contrast between GALE and its predecessor programs was its holistic integration of previously separate or sequential processes. In earlier language research pro

  17. Trusted Remote Operation of Proximate Emergy Robots (TROOPER): DARPA Robotics Challenge

    Science.gov (United States)

    2015-12-01

    method for activating the drill is to press the button by visual servoing in with the POKEY stick, described below. 3.3.5.4 Button Tracking and Stick...involving visual servoing much easier to accomplish. Figure 7. POKEY Stick Since the camera is mounted at a more maneuverable position (i.e., end...In the wall task, the cutting tool can be activated using a visual servoing approach to find the button with the hand camera then steadily move

  18. Trusted Remote Operation of Proximate Emergency Robots (TROOPER): DARPA Robotics Challenge

    Science.gov (United States)

    2015-12-01

    method for activating the drill is to press the button by visual servoing in with the POKEY stick, described below. 3.3.5.4 Button Tracking and Stick...involving visual servoing much easier to accomplish. Figure 7. POKEY Stick Since the camera is mounted at a more maneuverable position (i.e., end...In the wall task, the cutting tool can be activated using a visual servoing approach to find the button with the hand camera then steadily move

  19. Tactile Gloves for Autonomous Grasping With the NASA/DARPA Robonaut

    Science.gov (United States)

    Martin, T. B.; Ambrose, R. O.; Diftler, M. A.; Platt, R., Jr.; Butzer, M. J.

    2004-01-01

    Tactile data from rugged gloves are providing the foundation for developing autonomous grasping skills for the NASA/DARPA Robonaut, a dexterous humanoid robot. These custom gloves compliment the human like dexterity available in the Robonaut hands. Multiple versions of the gloves are discussed, showing a progression in using advanced materials and construction techniques to enhance sensitivity and overall sensor coverage. The force data provided by the gloves can be used to improve dexterous, tool and power grasping primitives. Experiments with the latest gloves focus on the use of tools, specifically a power drill used to approximate an astronaut's torque tool.

  20. DARPA Antibody Technology Program. Standardized Test Bed for Antibody Characterization: Characterization of an MS2 ScFv Antibody Produced by Illumina

    Science.gov (United States)

    2016-08-01

    ECBC-TR-1395 DARPA ANTIBODY TECHNOLOGY PROGRAM STANDARDIZED TEST BED FOR... ANTIBODY CHARACTERIZATION: CHARACTERIZATION OF AN MS2 SCFV ANTIBODY PRODUCED BY ILLUMINA Patricia E. Buckley Alena M. Calm Heather Welsh Roy...4. TITLE AND SUBTITLE DARPA Antibody Technology Program Standardized Test Bed for Antibody Characterization: Characterization of an MS2 ScFv

  1. Using physics-based pose predictions and free energy perturbation calculations to predict binding poses and relative binding affinities for FXR ligands in the D3R Grand Challenge 2

    Science.gov (United States)

    Athanasiou, Christina; Vasilakaki, Sofia; Dellis, Dimitris; Cournia, Zoe

    2018-01-01

    Computer-aided drug design has become an integral part of drug discovery and development in the pharmaceutical and biotechnology industry, and is nowadays extensively used in the lead identification and lead optimization phases. The drug design data resource (D3R) organizes challenges against blinded experimental data to prospectively test computational methodologies as an opportunity for improved methods and algorithms to emerge. We participated in Grand Challenge 2 to predict the crystallographic poses of 36 Farnesoid X Receptor (FXR)-bound ligands and the relative binding affinities for two designated subsets of 18 and 15 FXR-bound ligands. Here, we present our methodology for pose and affinity predictions and its evaluation after the release of the experimental data. For predicting the crystallographic poses, we used docking and physics-based pose prediction methods guided by the binding poses of native ligands. For FXR ligands with known chemotypes in the PDB, we accurately predicted their binding modes, while for those with unknown chemotypes the predictions were more challenging. Our group ranked #1st (based on the median RMSD) out of 46 groups, which submitted complete entries for the binding pose prediction challenge. For the relative binding affinity prediction challenge, we performed free energy perturbation (FEP) calculations coupled with molecular dynamics (MD) simulations. FEP/MD calculations displayed a high success rate in identifying compounds with better or worse binding affinity than the reference (parent) compound. Our studies suggest that when ligands with chemical precedent are available in the literature, binding pose predictions using docking and physics-based methods are reliable; however, predictions are challenging for ligands with completely unknown chemotypes. We also show that FEP/MD calculations hold predictive value and can nowadays be used in a high throughput mode in a lead optimization project provided that crystal structures of

  2. Grand Challenges in School Social Work: Collaboration and Constraint in School Social Workers' Sexuality Support for Children with Disabilities

    Science.gov (United States)

    Bolin, Sharon J.; Rueda, Heidi Adams; Linton, Kristen F.

    2018-01-01

    Children with disabilities (CWD) face challenges to the development of their sexuality, in part due to a lack of appropriate, tailored sexual education in schools, role ambiguity regarding provision of sexual health services, and widespread discomfort with the topic. However, CWD have unique sexual health needs, an increased vulnerability to…

  3. Ranking docking poses by graph matching of protein-ligand interactions: lessons learned from the D3R Grand Challenge 2

    Science.gov (United States)

    da Silva Figueiredo Celestino Gomes, Priscila; Da Silva, Franck; Bret, Guillaume; Rognan, Didier

    2018-01-01

    A novel docking challenge has been set by the Drug Design Data Resource (D3R) in order to predict the pose and affinity ranking of a set of Farnesoid X receptor (FXR) agonists, prior to the public release of their bound X-ray structures and potencies. In a first phase, 36 agonists were docked to 26 Protein Data Bank (PDB) structures of the FXR receptor, and next rescored using the in-house developed GRIM method. GRIM aligns protein-ligand interaction patterns of docked poses to those of available PDB templates for the target protein, and rescore poses by a graph matching method. In agreement with results obtained during the previous 2015 docking challenge, we clearly show that GRIM rescoring improves the overall quality of top-ranked poses by prioritizing interaction patterns already visited in the PDB. Importantly, this challenge enables us to refine the applicability domain of the method by better defining the conditions of its success. We notably show that rescoring apolar ligands in hydrophobic pockets leads to frequent GRIM failures. In the second phase, 102 FXR agonists were ranked by decreasing affinity according to the Gibbs free energy of the corresponding GRIM-selected poses, computed by the HYDE scoring function. Interestingly, this fast and simple rescoring scheme provided the third most accurate ranking method among 57 contributions. Although the obtained ranking is still unsuitable for hit to lead optimization, the GRIM-HYDE scoring scheme is accurate and fast enough to post-process virtual screening data.

  4. Binding free energy predictions of farnesoid X receptor (FXR) agonists using a linear interaction energy (LIE) approach with reliability estimation: application to the D3R Grand Challenge 2

    Science.gov (United States)

    Rifai, Eko Aditya; van Dijk, Marc; Vermeulen, Nico P. E.; Geerke, Daan P.

    2018-01-01

    Computational protein binding affinity prediction can play an important role in drug research but performing efficient and accurate binding free energy calculations is still challenging. In the context of phase 2 of the Drug Design Data Resource (D3R) Grand Challenge 2 we used our automated eTOX ALLIES approach to apply the (iterative) linear interaction energy (LIE) method and we evaluated its performance in predicting binding affinities for farnesoid X receptor (FXR) agonists. Efficiency was obtained by our pre-calibrated LIE models and molecular dynamics (MD) simulations at the nanosecond scale, while predictive accuracy was obtained for a small subset of compounds. Using our recently introduced reliability estimation metrics, we could classify predictions with higher confidence by featuring an applicability domain (AD) analysis in combination with protein-ligand interaction profiling. The outcomes of and agreement between our AD and interaction-profile analyses to distinguish and rationalize the performance of our predictions highlighted the relevance of sufficiently exploring protein-ligand interactions during training and it demonstrated the possibility to quantitatively and efficiently evaluate if this is achieved by using simulation data only.

  5. Evaluation and comparison of 3D intervertebral disc localization and segmentation methods for 3D T2 MR data: A grand challenge.

    Science.gov (United States)

    Zheng, Guoyan; Chu, Chengwen; Belavý, Daniel L; Ibragimov, Bulat; Korez, Robert; Vrtovec, Tomaž; Hutt, Hugo; Everson, Richard; Meakin, Judith; Andrade, Isabel Lŏpez; Glocker, Ben; Chen, Hao; Dou, Qi; Heng, Pheng-Ann; Wang, Chunliang; Forsberg, Daniel; Neubert, Aleš; Fripp, Jurgen; Urschler, Martin; Stern, Darko; Wimmer, Maria; Novikov, Alexey A; Cheng, Hui; Armbrecht, Gabriele; Felsenberg, Dieter; Li, Shuo

    2017-01-01

    The evaluation of changes in Intervertebral Discs (IVDs) with 3D Magnetic Resonance (MR) Imaging (MRI) can be of interest for many clinical applications. This paper presents the evaluation of both IVD localization and IVD segmentation methods submitted to the Automatic 3D MRI IVD Localization and Segmentation challenge, held at the 2015 International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI2015) with an on-site competition. With the construction of a manually annotated reference data set composed of 25 3D T2-weighted MR images acquired from two different studies and the establishment of a standard validation framework, quantitative evaluation was performed to compare the results of methods submitted to the challenge. Experimental results show that overall the best localization method achieves a mean localization distance of 0.8 mm and the best segmentation method achieves a mean Dice of 91.8%, a mean average absolute distance of 1.1 mm and a mean Hausdorff distance of 4.3 mm, respectively. The strengths and drawbacks of each method are discussed, which provides insights into the performance of different IVD localization and segmentation methods. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Scientific Grand Challenges: Discovery In Basic Energy Sciences: The Role of Computing at the Extreme Scale - August 13-15, 2009, Washington, D.C.

    Energy Technology Data Exchange (ETDEWEB)

    Galli, Giulia [Univ. of California, Davis, CA (United States). Workshop Chair; Dunning, Thom [Univ. of Illinois, Urbana, IL (United States). Workshop Chair

    2009-08-13

    The U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) and Office of Advanced Scientific Computing Research (ASCR) workshop in August 2009 on extreme-scale computing provided a forum for more than 130 researchers to explore the needs and opportunities that will arise due to expected dramatic advances in computing power over the next decade. This scientific community firmly believes that the development of advanced theoretical tools within chemistry, physics, and materials science—combined with the development of efficient computational techniques and algorithms—has the potential to revolutionize the discovery process for materials and molecules with desirable properties. Doing so is necessary to meet the energy and environmental challenges of the 21st century as described in various DOE BES Basic Research Needs reports. Furthermore, computational modeling and simulation are a crucial complement to experimental studies, particularly when quantum mechanical processes controlling energy production, transformations, and storage are not directly observable and/or controllable. Many processes related to the Earth’s climate and subsurface need better modeling capabilities at the molecular level, which will be enabled by extreme-scale computing.

  7. Grand Hotel prijutil hudozhnikov

    Index Scriptorium Estoniae

    2004-01-01

    Raadioajakirjanik Lea Veelmaa lindistas "Kunstikanali" 2004. a. esimese saate Grand Hotel Viljandis. Saatekülaliseks oli maalikunstnik Andres Tolts. Toltsi kaheksa akrüülmaali on eksponeeritud hotelli fuajees ja restoranis

  8. Grand Mal Seizure

    Science.gov (United States)

    ... grand mal seizures include: A family history of seizure disorders Any injury to the brain from trauma, a ... the risk of birth defects. If you have epilepsy and plan to become pregnant, work with your ...

  9. Aligning innovation with grand societal challenges

    DEFF Research Database (Denmark)

    Ricard, Lykke Margot

    2016-01-01

    This paper investigates the European Technology Platforms (ETPs) in wind power and in CO2 capture and storage supported by the European Commission (EC). It examines the role of these Platforms in shaping the trajectory of European energy technology policy, and shows that the EC’s support for the ......This paper investigates the European Technology Platforms (ETPs) in wind power and in CO2 capture and storage supported by the European Commission (EC). It examines the role of these Platforms in shaping the trajectory of European energy technology policy, and shows that the EC’s support...... for the ETPs marks a change from a solely evidence-based policy approach to the use of bottom-up policies designed to mobilize human capital based on social actors’ expectations, uncertainties and visions. These two ETPs include hitherto missing ‘key players’ who can enhance commercial legitimacy on both...... a valuable first qualitative analysis of this phenomenon which is emerging as a new policy instrument....

  10. Grand Challenges: Nanotechnology and the Social Studies

    Science.gov (United States)

    Manfra, Meghan McGlinn

    2013-01-01

    This article explores a multidisciplinary lesson on nanotechnology that can provide an effective means for teaching about both STEM and social studies topics. This approach encourages students to consider the "role that science and technology play in our lives and in our cultures." The extraordinary promise of nanotechnology, however, is…

  11. Density-functional expansion methods: Grand challenges.

    Science.gov (United States)

    Giese, Timothy J; York, Darrin M

    2012-03-01

    We discuss the source of errors in semiempirical density functional expansion (VE) methods. In particular, we show that VE methods are capable of well-reproducing their standard Kohn-Sham density functional method counterparts, but suffer from large errors upon using one or more of these approximations: the limited size of the atomic orbital basis, the Slater monopole auxiliary basis description of the response density, and the one- and two-body treatment of the core-Hamiltonian matrix elements. In the process of discussing these approximations and highlighting their symptoms, we introduce a new model that supplements the second-order density-functional tight-binding model with a self-consistent charge-dependent chemical potential equalization correction; we review our recently reported method for generalizing the auxiliary basis description of the atomic orbital response density; and we decompose the first-order potential into a summation of additive atomic components and many-body corrections, and from this examination, we provide new insights and preliminary results that motivate and inspire new approximate treatments of the core-Hamiltonian.

  12. The 'Grand Paris' project: Tools and challenges

    OpenAIRE

    De Palma, André

    2011-01-01

    The purpose of this Round Table is to assess the economic effects of major transport infrastructure projects. The term major projects is used to designate qualitative leaps, be it the mapping out of new road or rail rings to link disparate radial penetration routes or the introduction of more-targeted innovations tackling frequency, speed or automation. (...)

  13. Google Earth Grand Tour Themes

    Science.gov (United States)

    De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.; Dordevic, M. M.

    2014-12-01

    As part of an NSF TUES Type 3 project entitled "Google Earth for Onsite and Distance Education (GEODE)," we are assembling a "Grand Tour" of locations on Earth and other terrestrial bodies that every geoscience student should know about and visit at least in virtual reality. Based on feedback from colleagues at previous meetings, we have identified nine Grand Tour themes: "Plates and Plumes," "Rocks and Regions," "Geology Through Time," "The Mapping Challenge*," "U.S. National Parks*," "The Magical Mystery Tour*," "Resources and Hazards," "Planets and Moons," and "Top of the Pops." Themes marked with an asterisk are most developed at this stage and will be demonstrated in real time. The Mapping Challenge invites students to trace geological contacts, measure bedding strike and dip and the plunge, trend, and facing of a fold. There is an advanced tool for modeling periclinal folds. The challenge is presented in a game-like format with an emphasis on puzzle-solving that will appeal to students regardless of gender. For the tour of U.S. national parks, we divided the most geologically important parks into four groups—Western Pacific, West Coast, Rockies, and East Coast. We are combining our own team's GigaPan imagery with imagery already available on the Internet. There is a great deal of imagery just waiting to be annotated for geological education purposes. The Magical Mystery Tour takes students to Google Streetview locations selected by instructors. Students are presented with questions or tasks and are given automatic feedback. Other themes are under development. Within each theme, we are crowd-sourcing contributions from colleagues and inviting colleagues to vote for or against proposed locations and student interactions. The GEODE team includes the authors and: Heather Almquist, Stephen Burgin, Cinzia Cervato, Gene Cooper, Paul Karabinos, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury.

  14. Democracy and "Grand" Corruption.

    Science.gov (United States)

    Rose-Ackerman, Susan

    1996-01-01

    Defines "grand" corruption as that occurring at the higher levels of a political system and involving large sums of money. Discusses the impact and incentives for this level of corruption as well as various government responses. Identifies multinational corporations as the major malefactors. (MJP)

  15. The GRANDE detector

    International Nuclear Information System (INIS)

    Adams, A.; Bond, R.; Coleman, L.; Rollefson, A.; Wold, D.; Bratton, C.B.; Gurr, H.; Kropp, W.; Nelson, M.; Price, L.R.; Reines, F.; Schultz, J.; Sobel, H.; Svoboda, R.; Yodh, G.; Burnett, T.; Chaloupka, V.; Wilkes, R.J.; Cherry, M.; Ellison, S.B.; Guzik, T.G.; Wefel, J.; Gaidos, J.; Loeffler, F.; Sembroski, G.; Wilson, C.; Goodman, J.; Haines, T.J.; Kielczewska, D.; Lane, C.; Steinberg, R.; Lieber, M.; Nagle, D.; Potter, M.; Tripp, R.

    1990-01-01

    In this paper we present a detector facility which meets the requirements outlined above for a next-generation instrument. GRANDE (Gamma Ray and Neutrino DEtector) is an imaging, water Cerenkov detector, which combines in one facility an extensive air shower array and a high-energy neutrino detector. (orig.)

  16. Triggering the GRANDE array

    International Nuclear Information System (INIS)

    Wilson, C.L.; Bratton, C.B.; Gurr, J.; Kropp, W.; Nelson, M.; Sobel, H.; Svoboda, R.; Yodh, G.; Burnett, T.; Chaloupka, V.; Wilkes, R.J.; Cherry, M.; Ellison, S.B.; Guzik, T.G.; Wefel, J.; Gaidos, J.; Loeffler, F.; Sembroski, G.; Goodman, J.; Haines, T.J.; Kielczewska, D.; Lane, C.; Steinberg, R.; Lieber, M.; Nagle, D.; Potter, M.; Tripp, R.

    1990-01-01

    A brief description of the Gamma Ray And Neutrino Detector Experiment (GRANDE) is presented. The detector elements and electronics are described. The trigger logic for the array is then examined. The triggers for the Gamma Ray and the Neutrino portions of the array are treated separately. (orig.)

  17. Grand-Bassam

    African Journals Online (AJOL)

    Geo

    l'estuaire du fleuve Comoé (Grand-Bassam, Côte d'Ivoire). Kouassi Laurent ADOPO1*, Apie Colette AKOBE1, Etche Mireille AMANI2,. Sylvain MONDE3 et Kouamé AKA3. (1)Laboratoire de Géologie Marine, Sédimentologie et Environnement, Centre de Recherche en Ecologie,. Université Felix Houphouet Boigny Abidjan, ...

  18. A Summary of the Rendezvous, Proximity Operations, Docking, and Undocking (RPODU) Lessons Learned from the Defense Advanced Research Project Agency (DARPA) Orbital Express (OE) Demonstration System Mission

    Science.gov (United States)

    Dennehy, Cornelius J.; Carpenter, James R.

    2011-01-01

    The Guidance, Navigation, and Control (GN&C) Technical Discipline Team (TDT) sponsored Dr. J. Russell Carpenter, a Navigation and Rendezvous Subject Matter Expert (SME) from NASA's Goddard Space Flight Center (GSFC), to provide support to the Defense Advanced Research Project Agency (DARPA) Orbital Express (OE) rendezvous and docking flight test that was conducted in 2007. When that DARPA OE mission was completed, Mr. Neil Dennehy, NASA Technical Fellow for GN&C, requested Dr. Carpenter document his findings (lessons learned) and recommendations for future rendezvous missions resulting from his OE support experience. This report captures lessons specifically from anomalies that occurred during one of OE's unmated operations.

  19. Grand unified theories

    International Nuclear Information System (INIS)

    Langacker, P.

    1981-01-01

    In this talk I discuss the present status of these theories and of their observational and experimental implications. In section II, I briefly review the standard SU 3 sup(c) x SU 2 x U 1 model of the strong and electroweak interactions. Although phenomenologically successful, the standard model leaves many questions unanswered. Some of these questions are addressed by grand unified theories, which are defined and discussed in Section III. The Georgi-Glashow SU 5 model is described, as are theories based on larger groups such as SO 10 , E 6 , or SO 16 . It is emphasized that there are many possible grand unified theories and that it is an experimental problem not only to test the basic ideas but to discriminate between models. (orig./HSI)

  20. Asymptotically safe grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Bajc, Borut [J. Stefan Institute,1000 Ljubljana (Slovenia); Sannino, Francesco [CP-Origins & the Danish IAS, University of Southern Denmark,Campusvej 55, DK-5230 Odense M (Denmark); Université de Lyon, France, Université Lyon 1, CNRS/IN2P3, UMR5822 IPNL,F-69622 Villeurbanne Cedex (France)

    2016-12-28

    Phenomenologically appealing supersymmetric grand unified theories have large gauge representations and thus are not asymptotically free. Their ultraviolet validity is limited by the appearance of a Landau pole well before the Planck scale. One could hope that these theories save themselves, before the inclusion of gravity, by generating an interacting ultraviolet fixed point, similar to the one recently discovered in non-supersymmetric gauge-Yukawa theories. Employing a-maximization, a-theorem, unitarity bounds, as well as positivity of other central charges we nonperturbatively rule out this possibility for a broad class of prime candidates of phenomenologically relevant supersymmetric grand unified theories. We also uncover candidates passing these tests, which have either exotic matter or contain one field decoupled from the superpotential. The latter class of theories contains a model with the minimal matter content required by phenomenology.

  1. LA GRANDE DESCENTE

    CERN Multimedia

    The first endcap disc of CMS being lowered slowly and carefully 100 m underground into the experimental cavern. The disc is one of 15 large pieces to make the grand descent.  The uniquely shaped slice, 16 m high, about 50 cm thick weighs 400 tonnes. The two HF that were lowered earlier in November can also be seen in the foreground and background.  

  2. DARPA Robotics Challenge (DRC) Using Human-Machine Teamwork to Perform Disaster Response with a Humanoid Robot

    Science.gov (United States)

    2017-02-01

    leverage our tools and skills to develop a system in which we can get the simulated government furnished equipment (GFE) robot to walk over various types...our control software to the constellation and made a small helper program that gave us the possibility to restart our control software should...avoided this way. - The time and bandwidth limits caused us to integrate helper tools based on computer vision and a microphone sensor into the robot

  3. Grande do Sul, Brasil

    Directory of Open Access Journals (Sweden)

    Denis Alcides-Rezende

    2008-01-01

    Full Text Available The objective of this work is to analyse the integration of information systems and information technology resources in the municipal planning of 14 small cities of Rio Grande do Sul (Brazil. The research methodology consisted of a multiple case study together with a convenient non-probabilistic sample chosen through a research protocol. The results demonstrate the difficulties of these cities to organise the municipal data as well as their struggle for accessibility of information and planning for management and control.

  4. Modeling Temporal Processes in Early Spacecraft Design: Application of Discrete-Event Simulations for Darpa's F6 Program

    Science.gov (United States)

    Dubos, Gregory F.; Cornford, Steven

    2012-01-01

    While the ability to model the state of a space system over time is essential during spacecraft operations, the use of time-based simulations remains rare in preliminary design. The absence of the time dimension in most traditional early design tools can however become a hurdle when designing complex systems whose development and operations can be disrupted by various events, such as delays or failures. As the value delivered by a space system is highly affected by such events, exploring the trade space for designs that yield the maximum value calls for the explicit modeling of time.This paper discusses the use of discrete-event models to simulate spacecraft development schedule as well as operational scenarios and on-orbit resources in the presence of uncertainty. It illustrates how such simulations can be utilized to support trade studies, through the example of a tool developed for DARPA's F6 program to assist the design of "fractionated spacecraft".

  5. Albuquerque/Middle Rio Grande Urban Waters Viewer

    Science.gov (United States)

    These data have been compiled in support of the Middle Rio Grande/Albuquerque Urban Waters Partnership for the region including Albuquerque, New Mexico.The Middle Rio Grande/Albuquerque Urban Waters Federal Partnership is co-chaired by the U.S. Dept. of Housing and Urban Development and the U.S. Environmental Protection Agency. There are also a number of other federal agencies engaged in projects with Tribal, State, and local officials, and community stakeholders. Like many western river ecosystems, the Middle Rio Grande faces numerous challenges in balancing competing needs within a finite water supply and other resource constrains. Historical practices by our ancestors and immigrants to the Middle Rio Grande have established the conditions that we have inherited. Long-term drought exacerbated by climate change is changing conditions that affect natural and human communities as we strive to improve our precious Rio Grande.The Middle Rio Grande/Albuquerque Urban Waters Federal Partnership will reconnect our urban communities, particularly those that are overburdened or economically distressed, with the waterway by improving coordination among federal agencies and collaborating with community-led revitalization efforts. Our projects will improve our community water systems and promote their economic, environmental and social benefits. Specifically, the Middle Rio Grande/Albuquerque Urban Waters Federal Partnership will support the development of the Valle de Oro

  6. Grand Fir Nutrient Management in the Inland Northwestern USA

    Directory of Open Access Journals (Sweden)

    Dennis R. Parent

    2016-11-01

    Full Text Available Grand fir (Abies grandis (Douglas ex D. Don Lindley is widely distributed in the moist forests of the Inland Northwest. It has high potential productivity, its growth being nearly equal to western white pine, the most productive species in the region. There are large standing volumes of grand fir in the region. Nutritionally, the species has higher foliage cation concentrations than associated conifers, especially potassium (K and calcium (Ca. In contrast, it has lower nitrogen (N foliage concentrations, which creates favorable nutrient balance on N-limited sites. Despite concentration differences, grand fir stores proportionally more nutrients per tree than associated species because of greater crown biomass. Although few fertilization trials have examined grand fir specifically, its response is inferred from its occurrence in many monitored mixed conifer stands. Fertilization trials including grand fir either as a major or minor component show that it has a strong diameter and height growth response ranging from 15% to 50% depending in part on site moisture availability and soil geology. Grand fir tends to have a longer response duration than other inland conifers. When executed concurrently with thinning, fertilization often increases the total response. Late rotation application of N provides solid investment returns in carefully selected stands. Although there are still challenges with the post-fertilization effects on tree mortality, grand fir will continue to be an important species with good economic values and beneficial responses to fertilization and nutrient management.

  7. Cassini's Grand Finale Overview

    Science.gov (United States)

    Spilker, L. J.

    2017-12-01

    After 13 years in orbit, the Cassini-Huygens Mission to Saturn ended in a science-rich blaze of glory. Cassini sent back its final bits of unique science data on September 15, 2017, as it plunged into Saturn's atmosphere, vaporizing and satisfying planetary protection requirements. Cassini's final phase covered roughly ten months and ended with the first time exploration of the region between the rings and planet. In late 2016 Cassini transitioned to a series of 20 Ring Grazing orbits with peripases just outside Saturn's F ring, providing close flybys of tiny ring moons, including Pan, Daphnis and Atlas, and high-resolution views of Saturn's A and F rings. A final Titan flyby in late April 2017 propelled Cassini across Saturn's main rings and into its Grand Finale orbits. Comprised of 22 orbits, Cassini repeatedly dove between Saturn's innermost rings and upper atmosphere to answer fundamental questions unattainable earlier in the mission. The last orbit turned the spacecraft into the first Saturn atmosphere probe. The Grand Finale orbits provided highest resolution observations of both the rings and Saturn, and in-situ sampling of the ring particle composition, Saturn's atmosphere, plasma, and innermost radiation belts. The gravitational field was measured to unprecedented accuracy, providing information on the interior structure of the planet, winds in the deeper atmosphere, and mass of the rings. The magnetic field provided insight into the physical nature of the magnetic dynamo and structure of the internal magnetic field. The ion and neutral mass spectrometer sampled the upper atmosphere for molecules that escape the atmosphere in addition to molecules originating from the rings. The cosmic dust analyzer directly sampled the composition from different parts of the main rings for the first time. Fields and particles instruments directly measured the plasma environment between the rings and planet. Science highlights and new mysteries collected in the Grand

  8. Grand unification and supergravity

    International Nuclear Information System (INIS)

    Nanopoulos, D.V.

    Grand Unified Theories (GUTs) are very successful, but they suffer from fine-tuning or hierarchy problems. It seems that more symmetry beyond the gauge symmetry is needed and indeed supersymmetric GUTs may provide the correct framework in solving the hierarchy problems. These are reviewed. From the results discussed, it is seen that for the first time in particle physics, gravity seems to play a dominant role. It may be responsible for GUT breaking, SU(2) x U(1) breaking, fermion masses, proton decay and a consistent cosmological picture. Supergravity seems to offer a consistent, effective theory for energies below the Planck scale to N=1 local SUSY but also, in the context of N=8 extended supergravity with a dynamically realized SU(8), there may be a consistent fundamental unified theory of all interactions. (U.K.)

  9. Grand unification: status report

    International Nuclear Information System (INIS)

    Georgi, H.

    1983-01-01

    Grand unification is reviewed with regard to the flavor puzzle and the hierarchy puzzle. Progress in CP and the PQWWKDFS axion is reviewed. The neutrino mass and B-L research, the understanding and assimilation of the language of effective theories (which divide the momentum scale up into regions), with focus on the models, are surveyed. Various unified models are organized according to whether they address the hierarchy puzzle or the flavor puzzle. SU(5), SO(10), E6, and Higgs are considered simple and explicit models. Global symmetry addresses hierarchy puzzle, but the rules are unclear. In SO (18), with regard to hierarchy, perturbation theory breaks down. SO (14) fails for hierarchy because of GIM, b and t problems. Supersymmetry and technicolor with regard to flavor puzzle are questioned. The CP solution of ETC and Composite C models (addressing both flavor and hierarchy) is a minus. Composite A model has no evident virtues, and the basic idea of ETC model needs checking

  10. Grand unified theories. Pt. 2

    International Nuclear Information System (INIS)

    Ellis, J.

    1982-01-01

    The author gives an introduction to the construction of grand unified theories on the base of the SU(3)xSU(2)xU(1) model of the strong, weak, and electromagnetic interactions. Especially he discusses the proton decay, neutrino masses and oscillations, and cosmological implications in connection with grand unified theories. (orig./HSI)

  11. La importancia de ser grande

    OpenAIRE

    Baisre, J. A.

    2007-01-01

    Se responde a las preguntas ¿por qué los mamíferos marinos son los animales más grandes del planeta?, ¿Por qué los peces no pueden ser más grandes?. Éstas y otras interrogantes son respondidas de forma sencilla y clara.

  12. Geo synthetics. a remarkable discipline with great achievements in the past and exciting challenges for a bright future; Geosinteticos: una importante disciplina con grandes logros en el pasado y emocionantes retos para un brillante futuro

    Energy Technology Data Exchange (ETDEWEB)

    Giroud, J. P.

    2014-02-01

    This paper presents achievements of the geo synthetics discipline and challenges facing the discipline. The paper shows that one of the main achievements of geo synthetics discipline and challenges facing the discipline. The paper shows that one of the main achievements of geo synthetics is that they have pervaded most branches of geotechnical engineering to the point where it is almost impossible to practice geotechnical engineering without geo synthetics. Then, the paper addresses the challenges facing the geo synthetics discipline. Two major types of challenges are identified: education challenges and technical challenges. Regarding technical challenges, it is recommended that researchers focus on behaviors that are not traditionally considered in geotechnical engineering in order to use geo synthetics to their full potential. Note: this is a significantly expanded version of the keynote paper presented at the 2008 GeoAmericas Conferences. (Author)

  13. Personal radiation detector at a high technology readiness level that satisfies DARPA's SN-13-47 and SIGMA program requirements

    Science.gov (United States)

    Ginzburg, D.; Knafo, Y.; Manor, A.; Seif, R.; Ghelman, M.; Ellenbogen, M.; Pushkarsky, V.; Ifergan, Y.; Semyonov, N.; Wengrowicz, U.; Mazor, T.; Kadmon, Y.; Cohen, Y.; Osovizky, A.

    2015-06-01

    There is a need to develop new personal radiation detector (PRD) technologies that can be mass produced. On August 2013, DARPA released a request for information (RFI) seeking innovative radiation detection technologies. In addition, on December 2013, a Broad Agency Announcement (BAA) for the SIGMA program was released. The RFI requirements focused on a sensor that should possess three main properties: low cost, high compactness and radioisotope identification capabilities. The identification performances should facilitate the detection of a hidden threat, ranging from special nuclear materials (SNM) to commonly used radiological sources. Subsequently, the BAA presented the specific requirements at an instrument level and provided a comparison between the current market status (state-of-the-art) and the SIGMA program objectives. This work presents an optional alternative for both the detection technology (sensor with communication output and without user interface) for DARPA's initial RFI and for the PRD required by the SIGMA program. A broad discussion is dedicated to the method proposed to fulfill the program objectives and to the selected alternative that is based on the PDS-GO design and technology. The PDS-GO is the first commercially available PRD that is based on a scintillation crystal optically coupled with a silicon photomultiplier (SiPM), a solid-state light sensor. This work presents the current performance of the instrument and possible future upgrades based on recent technological improvements in the SiPM design. The approach of utilizing the SiPM with a commonly available CsI(Tl) crystal is the key for achieving the program objectives. This approach provides the appropriate performance, low cost, mass production and small dimensions; however, it requires a creative approach to overcome the obstacles of the solid-state detector dark current (noise) and gain stabilization over a wide temperature range. Based on the presented results, we presume that

  14. Grand slam on cancer.

    Science.gov (United States)

    Gartrell, Nanette

    2014-01-01

    A winner of 59 Grand Slam championships including a record 9 Wimbledon singles titles, Martina Navratilova is the most successful woman tennis player of the modern era. Martina was inducted into the International Tennis Hall of Fame, named "Tour Player of the Year" seven times by the Women's Tennis Association, declared "Female Athlete of the Year" by the Associated Press, and ranked one of the "Top Forty Athletes of All-Time" by Sports Illustrated. Equally accomplished off the court, Martina is an author, philanthropist, TV commentator, and activist who has dedicated her life to educating people about prejudice and stereotypes. After coming out as a lesbian in 1981, Martina became a tireless advocate of equal rights for lesbian, gay, bisexual, and transgender (LGBT) people, and she has contributed generously to the LGBT community. Martina is the author of seven books, including most recently Shape Your Self: My 6-Step Diet and Fitness Plan to Achieve the Best Shape of your Life, an inspiring guide to healthy living and personal fitness. Martina was diagnosed with breast cancer in 2010.

  15. Magnetic spectrometer Grand Raiden

    International Nuclear Information System (INIS)

    Fujiwara, M.; Akimune, H.; Daito, I.; Fujimura, H.; Fujita, Y.; Hatanaka, K.; Ikegami, H.; Katayama, I.; Nagayama, K.; Matsuoka, N.; Morinobu, S.; Noro, T.; Yoshimura, M.; Sakaguchi, H.; Sakemi, Y.; Tamii, A.; Yosoi, M.

    1999-01-01

    A high-resolution magnetic spectrometer called 'Grand Raiden' is operated at the RCNP ring cyclotron facility in Osaka for nuclear physics studies at intermediate energies. This magnetic spectrometer has excellent ion-optical properties. In the design of the spectrometer, the second-order dispersion matching condition has been taken into account, and almost all the aberration terms such as (x vertical bar θ 3 ), (x vertical bar θφ 2 ), (x vertical bar θ 2 δ) and (x vertical bar θδ 2 ) in a third-order matrix calculation are optimized. A large magnetic rigidity of the spectrometer (K = 1400 MeV) gives a great advantage to measure the charge-exchange ( 3 He, t) reactions at 450 MeV. The ability of the high-resolution measurement has been demonstrated. Various coincidence measurements are performed to study the nuclear structures of highly excited states through decay properties of nuclear levels following nuclear reactions at intermediate energies

  16. Clinical physiology grand rounds.

    Science.gov (United States)

    Richards, Jeremy; Schwartzstein, Richard; Irish, Julie; Almeida, Jacqueline; Roberts, David

    2013-04-01

    Clinical Physiology Grand Rounds (CPGR) is an interactive, case-based conference for medical students designed to: (1) integrate preclinical and clinical learning; (2) promote inductive clinical reasoning; and (3) emphasise students as peer teachers. CPGR specifically encourages mixed learning level student interactions and emphasises the use of concept mapping. We describe the theoretical basis and logistical considerations for an interactive, integrative, mixed-learner environment such as CPGR. In addition, we report qualitative data regarding students' attitudes towards and perceptions of CPGR. Medical students from first to fourth year participate in a monthly, interactive conference. The CPGR was designed to bridge gaps and reinforce linkages between basic science and clinical concepts, and to incorporate interactive vertical integration between preclinical and clinical students. Medical education and content experts use Socratic, interactive teaching methods to develop real-time concept maps to emphasise the presence and importance of linkages across curricula. Student focus groups were held to assess attitudes towards and perceptions of the mixed-learner environment and concept maps in CPGR. Qualitative analyses of focus group transcripts were performed to develop themes and codes describing the students' impressions of CPGR. CPGR is a case-based, interactive conference designed to help students gain an increased appreciation of linkages between basic science and clinical medicine concepts, and an increased awareness of clinical reasoning thought processes. Success is dependent upon explicit attention being given to goals for students' integrated learning. © Blackwell Publishing Ltd 2013.

  17. Adversarial reasoning: challenges and approaches

    Science.gov (United States)

    Kott, Alexander; Ownby, Michael

    2005-05-01

    This paper defines adversarial reasoning as computational approaches to inferring and anticipating an enemy's perceptions, intents and actions. It argues that adversarial reasoning transcends the boundaries of game theory and must also leverage such disciplines as cognitive modeling, control theory, AI planning and others. To illustrate the challenges of applying adversarial reasoning to real-world problems, the paper explores the lessons learned in the CADET -- a battle planning system that focuses on brigade-level ground operations and involves adversarial reasoning. From this example of current capabilities, the paper proceeds to describe RAID -- a DARPA program that aims to build capabilities in adversarial reasoning, and how such capabilities would address practical requirements in Defense and other application areas.

  18. SO(10) supersymmetric grand unified theories

    Science.gov (United States)

    Dermisek, Radovan

    The origin of the fermion mass hierarchy is one of the most challenging problems in elementary particle physics. In the standard model fermion masses and mixing angles are free parameters. Supersymmetric grand unified theories provide a beautiful framework for physics beyond the standard model. In addition to gauge coupling unification these theories provide relations between quark and lepton masses within families, and with additional family symmetry the hierarchy between families can be generated. We present a predictive SO(10) supersymmetric grand unified model with D 3 x U(1) family symmetry. The hierarchy in fermion masses is generated by the family symmetry breaking D 3 x U(1) → ZN → nothing. This model fits the low energy data in the charged fermion sector quite well. We discuss the prediction of this model for the proton lifetime in light of recent SuperKamiokande results and present a clear picture of the allowed spectra of supersymmetric particles. Finally, the detailed discussion of the Yukawa coupling unification of the third generation particles is provided. We find a narrow region is consistent with t, b, tau Yukawa unification for mu > 0 (suggested by b → sgamma and the anomalous magnetic moment of the muon) with A0 ˜ -1.9m16, m10 ˜ 1.4m16, m16 ≳ 1200 GeV and mu, M1/2 ˜ 100--500 GeV. Demanding Yukawa unification thus makes definite predictions for Higgs and sparticle masses.

  19. Selected topics in grand unification

    International Nuclear Information System (INIS)

    Seckel, D.

    1983-01-01

    This dissertation is a collection of four pieces of research dealing with grand unification. The topics are neutron oscillation, CP violation, magnetic monopole abundance and distribution in neutron stars, and a proposal for an inflationary cosmology driven by stress-energy in domain walls

  20. Introduction to grand unification theories

    International Nuclear Information System (INIS)

    Kang, Kyungsik

    1980-01-01

    We introduce the Georgi-Glashow model based on the minimal gauge group SU(5) as a prototype grand unification theory of the electroweak and strong interactions. Simple estimation of sin 2 thetasub(W) in the symmetry limit and the renormalization corrections at the energy scale of Msub(W) are given along wich other successes of the SU(5) model

  1. Saturn's Internal Magnetic Field Revealed by Cassini Grand Finale

    Science.gov (United States)

    Cao, H.; Dougherty, M. K.; Khurana, K. K.; Hunt, G. J.; Provan, G.; Kellock, S.; Burton, M. E.; Burk, T. A.

    2017-12-01

    Saturn's internal magnetic field has been puzzling since the first in-situ measurements during the Pioneer 11 Saturn flyby. Cassini magnetometer measurements prior to the Grand Finale phase established 1) the highly axisymmetric nature of Saturn's internal magnetic field with a dipole tilt smaller than 0.06 degrees, 2) at least an order of magnitude slower secular variation rate compared to that of the current geomagnetic field, and 3) expulsion of magnetic fluxes from the equatorial region towards high latitude. The highly axisymmetric nature of Saturn's intrinsic magnetic field not only challenges dynamo theory but also makes an accurate determination of the interior rotation rate of Saturn extremely difficult. The Cassini spacecraft entered the Grand Finale phase in April 2017, during which time the spacecraft dived through the gap between Saturn's atmosphere and the inner edge of the D-ring 22 times before descending into the deep atmosphere of Saturn. The unprecedented proximity to Saturn (reaching 2500 km above the cloud deck) and the highly inclined nature of the Grand Finale orbits provided an ideal opportunity to decode Saturn's internal magnetic field. The fluxgate magnetometer onboard Cassini made precise vector measurements during the Grand Finale phase. Magnetic signals from the interior of the planet, the magnetospheric ring current, the high-latitude field-aligned current (FAC) modulated by the 10.7 hour planetary period oscillation, and low-latitude FACs were observed during the Grand Finale phase. Here we report the magnetometer measurements during the Cassini Grand Finale phase, new features of Saturn's internal magnetic field revealed by these measurements (e.g., the high degree magnetic moments of Saturn, the level of axisymmetry beyond dipole), and implications for the deep interior of Saturn.

  2. Results from KASCADE–Grande

    International Nuclear Information System (INIS)

    Bertaina, M.; Apel, W.D.; Arteaga-Velázquez, J.C.; Bekk, K.; Blümer, J.; Bozdog, H.; Brancus, I.M.; Buchholz, P.; Cantoni, E.; Chiavassa, A.; Cossavella, F.

    2012-01-01

    The KASCADE–Grande experiment, located at Karlsruhe Institute of Technology (Germany) is a multi-component extensive air-shower experiment devoted to the study of cosmic rays and their interactions at primary energies 10 14 –10 18 eV. Main goals of the experiment are the measurement of the all-particle energy spectrum and mass composition in the 10 16 –10 18 eV range by sampling charged (N ch ) and muon (N μ ) components of the air shower. The method to derive the energy spectrum and its uncertainties, as well as the implications of the obtained result, is discussed. An overview of the analyses performed by KASCADE–Grande to derive the mass composition of the measured high-energy comic rays is presented as well.

  3. Results from KASCADE-Grande

    Energy Technology Data Exchange (ETDEWEB)

    Bertaina, M., E-mail: bertaina@to.infn.it [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Apel, W.D. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Arteaga-Velazquez, J.C. [Universidad Michoacana, Instituto de Fisica y Matematicas, Morelia (Mexico); Bekk, K. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Bluemer, J. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Institut fuer Experimentelle Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Bozdog, H. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Brancus, I.M. [National Institute of Physics and Nuclear Engineering, Bucharest (Romania); Buchholz, P. [Fachbereich Physik, Universitaet Siegen (Germany); Cantoni, E. [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Istituto di Fisica dello Spazio Interplanetario, INAF Torino (Italy); Chiavassa, A. [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Cossavella, F. [Institut fuer Experimentelle Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); and others

    2012-11-11

    The KASCADE-Grande experiment, located at Karlsruhe Institute of Technology (Germany) is a multi-component extensive air-shower experiment devoted to the study of cosmic rays and their interactions at primary energies 10{sup 14}-10{sup 18} eV. Main goals of the experiment are the measurement of the all-particle energy spectrum and mass composition in the 10{sup 16}-10{sup 18} eV range by sampling charged (N{sub ch}) and muon (N{sub {mu}}) components of the air shower. The method to derive the energy spectrum and its uncertainties, as well as the implications of the obtained result, is discussed. An overview of the analyses performed by KASCADE-Grande to derive the mass composition of the measured high-energy comic rays is presented as well.

  4. Software Engineering Support of the Third Round of Scientific Grand Challenge Investigations: An Earth Modeling System Software Framework Strawman Design that Integrates Cactus and UCLA/UCB Distributed Data Broker

    Science.gov (United States)

    Talbot, Bryan; Zhou, Shu-Jia; Higgins, Glenn

    2002-01-01

    One of the most significant challenges in large-scale climate modeling, as well as in high-performance computing in other scientific fields, is that of effectively integrating many software models from multiple contributors. A software framework facilitates the integration task. both in the development and runtime stages of the simulation. Effective software frameworks reduce the programming burden for the investigators, freeing them to focus more on the science and less on the parallel communication implementation, while maintaining high performance across numerous supercomputer and workstation architectures. This document proposes a strawman framework design for the climate community based on the integration of Cactus, from the relativistic physics community, and UCLA/UCB Distributed Data Broker (DDB) from the climate community. This design is the result of an extensive survey of climate models and frameworks in the climate community as well as frameworks from many other scientific communities. The design addresses fundamental development and runtime needs using Cactus, a framework with interfaces for FORTRAN and C-based languages, and high-performance model communication needs using DDB. This document also specifically explores object-oriented design issues in the context of climate modeling as well as climate modeling issues in terms of object-oriented design.

  5. Cassini's Grand Finale Science Highlights

    Science.gov (United States)

    Spilker, Linda

    2017-10-01

    After 13 years in orbit, the Cassini-Huygens Mission to Saturn ended in a science-rich blaze of glory. Cassini returned its final bits of unique science data on September 15, 2017, as it plunged into Saturn's atmosphere satisfying planetary protection requirements. Cassini's Grand Finale covered a period of roughly five months and ended with the first time exploration of the region between the rings and planet.The final close flyby of Titan in late April 2017 propelled Cassini across Saturn’s main rings and into its Grand Finale orbits; 22 orbits that repeatedly dove between Saturn’s innermost rings and upper atmosphere making Cassini the first spacecraft to explore this region. The last orbit turned the spacecraft into the first Saturn upper atmospheric probe.The Grand Finale orbits provided highest resolution observations of both the rings and Saturn, and in-situ sampling of the ring particle composition, Saturn's atmosphere, plasma, and innermost radiation belts. The gravitational field was measured to unprecedented accuracy, providing information on the interior structure of the planet, winds in the deeper atmosphere, and mass of the rings. The magnetic field provided insight into the physical nature of the magnetic dynamo and structure of the internal magnetic field. The ion and neutral mass spectrometer sampled the upper atmosphere for molecules that escape the atmosphere in addition to molecules originating from the rings. The cosmic dust analyzer directly sampled the composition from different parts of the main rings for the first time. Fields and particles instruments directly measured the plasma environment between the rings and planet.Science highlights and new mysteries gleaned to date from the Grand Finale orbits will be discussed.The research described in this paper was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. Copyright 2017

  6. Grandes números primos

    OpenAIRE

    Bang, Thöger

    2012-01-01

    En las escuelas danesas la teoría de los números se ha ido restringiendo gradualmente hasta no incluir sino la demostración de la descomposición univoca de los números enteros en números primos y la demostración del teorema clásico de EUCLIDES sobre la existencia de un número primo arbitrariamente grande.

  7. DARPA Quantum Network Testbed

    Science.gov (United States)

    2007-07-01

    Antonio Bovino, Pietro Varisco, Anna Maria Colla, Giuseppe Castagnoli, Giovanni Di Giuseppe and Alexander V. Sergienko “Effective Fiber-Coupling of...Giovanni Di Giuseppe Brian Imhausen Harvard University Teammate John Myers Tai Wu Leo Donnelly NIST Teammate Sae Woo Nam Bob Schwall Robert...A. M. Colla, G. Castagnoli, G. Di Giuseppe, and A. V. Sergienko, “Practical Quantum Key Distribution Using Polarization Entangled States

  8. DARPA ADAMS Project

    Science.gov (United States)

    2015-05-11

    it means that Mary distrusts John. We showed that it is possible to analyze such trust- distrust relationships within signed social networks in... relationship problems) − Professional Problems (negative changes at workplace, interpersonal conflicts) Furthermore, we encode in 2nd degree variables...a social media forum data. • Processed initial set of Vegas metrics data (clustering coefficient, # similar users, # skip levels) through time

  9. DARPA TRADES Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Aguilo Valentin, Miguel Alejandro [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Trujillo, Susie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-02-01

    During calendar year 2017, Sandia National Laboratories (SNL) made strides towards developing an open portable design platform rich in highperformance computing (HPC) enabled modeling, analysis and synthesis tools. The main focus was to lay the foundations of the core interfaces that will enable plug-n-play insertion of synthesis optimization technologies in the areas of modeling, analysis and synthesis.

  10. DARPA Emerging Technologies

    Science.gov (United States)

    2016-01-01

    American Security, April 2015), https://www.cnas.org/sites/default/files/ publica tions-pdf/CNAS_Directed_Energy_Weapons_April-2015.pdf. Disclaimer The views...and opinions expressed or implied in SSQ are those of the authors and are not officially sanctioned by any agency or department of the US

  11. Grand unification theory and technicolor

    International Nuclear Information System (INIS)

    Rubakov, V.A.; Shaposhnikov, M.E.

    1983-01-01

    The lecture course can be considered as introduction to the problems concerning grand unification models. The course is incomplete. Such problems as CP-violations in strong interactions and the problem of gravitational interaction inclusion in the scheme of grand unification theory are not touched upon. Models of early unification, in which strong, weak and electromagnetic interactions are compared according to the ''strength'' at energies of about 10 5 -10 6 GeV, are not discussed. Models with horizontal symmetry, considering different generations of quarks and leptons from one viewpoint, are not analyzed. Cosmological applications of supersymmetric unified theories are not considered. Certain problems of standard elementary particle theory, philosophy of the great unification, general properties of the grand unification models and the main principles of the construction of models: the SU(5) model, models on the SO(10) groups, have been considered. The problem of supersymmetric unification hierarchies, supersymmetric generalization of the minimum SU(5) model, supersymmetry violation and the problem of hierarchies, phenomenology of the o.rand unification models, cosmological application and technicolour, are discussed

  12. Grand unification: quo vadis domine

    International Nuclear Information System (INIS)

    Senjanovic, G.

    1985-01-01

    The present theoretical and experimental situation with grand unification is summarized. The issues of proton decay and the Weinberg angle are addressed, going through the predictions of both the standard SU(5) theory and its supersymmetric extension. The SO(10) theory, which provides a minimal one family model, is then studied. The gravitational characteristics of domain walls and strings are then discussed. It is argued that there is a need to go beyond SO(10) in order to incorporate a unified picture of families. This leads to the prediction of mirror fermions, whose physics is analyzed. 31 refs

  13. Graafikatriennaali grand prix Korea kunstnikule

    Index Scriptorium Estoniae

    1998-01-01

    Tallinna XI graafikatriennaali rahvusvaheline žürii andis grand prix korea kunstnikule Chung¡Sang-Gonile, kolm võrdset preemiat - soome kunstnikele Anita Jensenile ja Tapani Mikkonenile ning jaapani kunstnikule Estuko Obatale. Eesti Kunstimuuseumi preemia - Wendy Swallow. Tallinna linna preemia ja Ivar Luki sponsoripreemia - Walter Jule. Sponsoripreemiad : Paletti Eesti AS preemia - Inga Heamägi; Rannila Profiili preemia - Mojca Zlokarnik; UNDP preemia - Andrea Juan. Rotermanni soolalao arhitektuuri- ja kunstikeskuse diplom - Lis Ingram, Heli Päivikki Kurunsaari, Randi Strand, Wendy Swallow

  14. Grand Challenges in Space Technology: Distributed Satellite Systems

    National Research Council Canada - National Science Library

    Miller, David

    2001-01-01

    The MITIAFRL Distributed Satellite Systems program examines the motivation, analysis and development of technology associated with the distribution of assets and functionality over a number of cooperating satellites...

  15. Science, technology and the 'grand challenge' of aging

    DEFF Research Database (Denmark)

    Jæger, Birgit; Peine, Alexander; Moors, Ellen

    2015-01-01

    In this paper, we introduce the themes addressed and the approaches used in this special issue. We start by briefly discussing the state of the art in research and policy making related to science, technology and ageing. We argue that an important gap characterizes this state of the art: current...... approaches do not consider material practice and materiality to be an inherent part of later life as constituted in contemporary societies. Science and Technology Studies (STS) provide both the theories and methods to address this gap, and thus deploy a theoretical and empirical understanding of science......, technology and ageing that captures how later life co-evolves with the practices of technology use and design. We briefly discuss how the articles in the collection each contribute to such an understanding across various locations. We conclude that, together, the contributions specify a perspective...

  16. Grand Challenges Learning Analytics and Open Online Onderwijs

    NARCIS (Netherlands)

    Manderveld, Jocelyn; Berg, Alan; Schuwer, Robert; Drachsler, Hendrik

    2018-01-01

    Als onderdeel van het programma voor open en online onderwijs werkt SURF samen met de hogescholen en universiteiten aan kennisontwikkeling op allerlei thema’s. Deze uitgave is een eerste verkenning van de mogelijkheden om learning analytics in te zetten bij open en online onderwijs en de uitdagingen

  17. Accelerating cooperative systems' development through the Grand Cooperative Driving challenge

    NARCIS (Netherlands)

    Vonk Noordegraaf, D.; Malone, K.M.; Katwijk, R. van; Gerrits, A.

    2009-01-01

    Cooperative driving systems comprise an important research area. They are considered a promising solution for reducing traffic congestion, reducing environmental impact and improving traffic safety and driver comfort. The key to these systems is the communication and interaction between vehicles and

  18. Grand Challenges in Physics Education Research: Teacher Preparation

    Science.gov (United States)

    Heron, Paula

    2015-04-01

    The courses, curricula and programs that produce new K-12 teachers have been the subject of research in the physics education community for many years. In terms of recruitment, curricula, and mentoring, programs and pathways vary considerably from institution to institution. Each program addresses many different aspects of teaching including knowledge of the content and familiarity with best teaching practices. At the same time, even within physics (or physical science) there is a broad range of student outcomes that are considered important, including acquisition of factual knowledge, development of skill with disciplinary practices, and positive attitudes toward the discipline and one's own abilities. Given the broad range of both input and outcome variables it is no surprise that there are very few clear answers about the impact of teacher preparation on teachers, students and society. In this talk I will summarize some of the main findings to date, and identify some areas where much more research is needed.

  19. The Grand Challenges of Command and Control Policy

    Science.gov (United States)

    2006-06-01

    Memetic Warfare Memes are ideas that can be modeled and simulated. In a modern journalistic environment, dynamic information feedback from the theater...output type such that both adversarial meme processes and our counter anti- memetic activity could be modeled, simulated, and assessed. I am now...opposing force of the consequence of using biological or chemical weapons on the invading American forces. Do we have the proper memetic dynamics

  20. Security and Privacy Grand Challenges for the Internet of Things

    Energy Technology Data Exchange (ETDEWEB)

    Fink, Glenn A.; Zarzhitsky, Dimitri V.; Carroll, Thomas E.; Farquhar, Ethan D.

    2015-08-20

    Abstract— The growth of the Internet of Things (IoT) is driven by market pressures, and while security is being considered, the relationship between the unintended consequences of billions of such devices connecting to the Internet cannot be described with existing mathematical methods. The possibilities for illicit surveillance through lifestyle analysis, unauthorized access to information, and new attack vectors will continue to increase by 2020, when up-to 50 billion devices may be connected. This paper discusses various kinds of vulnerabilities that can be expected to arise, and presents a research agenda for mitigating the worst of the impacts. We hope to draw research attention to the potential dangers of IoT so that many of these problems can be avoided.

  1. Face recognition's grand challenge: uncontrolled conditions under control

    NARCIS (Netherlands)

    Boom, B.J.

    2010-01-01

    The number of cameras increases rapidly in squares, shopping centers, railway stations and airport halls. There are hundreds of cameras in the city center of Amsterdam. This is still modest compared to the tens of thousands of cameras in London, where citizens are expected to be filmed by more than

  2. Grand Challenge Portfolio: Driving Innovation in Industrial Energy Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-01-04

    Under the Recovery Act, AMO provided cost-shared funding for early-stage, low-cost, "concept definition studies" of 47 promising innovations for next-generation manufacturing, energy-intensive processes, advanced materials, and greenhouse gas emissions reduction. The brochure provides information on each of these projects.

  3. Flexible Environments for Grand-Challenge Simulation in Climate Science

    Science.gov (United States)

    Pierrehumbert, R.; Tobis, M.; Lin, J.; Dieterich, C.; Caballero, R.

    2004-12-01

    Current climate models are monolithic codes, generally in Fortran, aimed at high-performance simulation of the modern climate. Though they adequately serve their designated purpose, they present major barriers to application in other problems. Tailoring them to paleoclimate of planetary simulations, for instance, takes months of work. Theoretical studies, where one may want to remove selected processes or break feedback loops, are similarly hindered. Further, current climate models are of little value in education, since the implementation of textbook concepts and equations in the code is obscured by technical detail. The Climate Systems Center at the University of Chicago seeks to overcome these limitations by bringing modern object-oriented design into the business of climate modeling. Our ultimate goal is to produce an end-to-end modeling environment capable of configuring anything from a simple single-column radiative-convective model to a full 3-D coupled climate model using a uniform, flexible interface. Technically, the modeling environment is implemented as a Python-based software component toolkit: key number-crunching procedures are implemented as discrete, compiled-language components 'glued' together and co-ordinated by Python, combining the high performance of compiled languages and the flexibility and extensibility of Python. We are incrementally working towards this final objective following a series of distinct, complementary lines. We will present an overview of these activities, including PyOM, a Python-based finite-difference ocean model allowing run-time selection of different Arakawa grids and physical parameterizations; CliMT, an atmospheric modeling toolkit providing a library of 'legacy' radiative, convective and dynamical modules which can be knitted into dynamical models, and PyCCSM, a version of NCAR's Community Climate System Model in which the coupler and run-control architecture are re-implemented in Python, augmenting its flexibility and adaptability.

  4. Facing the Grand Challenges through Heuristics and Mindfulness

    Science.gov (United States)

    Powietrzynska, Malgorzata; Tobin, Kenneth; Alexakos, Konstantinos

    2015-01-01

    We address the nature of mindfulness and its salience to education generally and to science education specifically. In a context of the historical embeddedness of mindfulness in Buddhism we discuss research in social neuroscience, presenting evidence for neuronal plasticity of the brain and six emotional styles, which are not biologically…

  5. Engineering central metabolism – a grand challenge for plant biologists

    DEFF Research Database (Denmark)

    Sweetlove, Lee J.; Nielsen, Jens; Fernie, Alisdair R.

    2017-01-01

    The goal of increasing crop productivity and nutrient-use efficiency is being addressed by a number of ambitious research projects seeking to re-engineer photosynthetic biochemistry. Many of these projects will require the engineering of substantial changes in fluxes of central metabolism. However......, as has been amply demonstrated in simpler systems such as microbes, central metabolism is extremely difficult to rationally engineer. This is because of multiple layers of regulation that operate to maintain metabolic steady state and because of the highly connected nature of central metabolism....... In this review we discuss new approaches for metabolic engineering that have the potential to address these problems and dramatically improve the success with which we can rationally engineer central metabolism in plants. In particular, we advocate the adoption of an iterative ‘design-build-test-learn’ cycle...

  6. Understanding rare disease pathogenesis: a grand challenge for model organisms.

    Science.gov (United States)

    Hieter, Philip; Boycott, Kym M

    2014-10-01

    In this commentary, Philip Hieter and Kym Boycott discuss the importance of model organisms for understanding pathogenesis of rare human genetic diseases, and highlight the work of Brooks et al., "Dysfunction of 60S ribosomal protein L10 (RPL10) disrupts neurodevelopment and causes X-linked microcephaly in humans," published in this issue of GENETICS. Copyright © 2014 by the Genetics Society of America.

  7. Proton hexality in local grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Foerste, Stefan; Nilles, Hans Peter [Bonn Univ. (Germany). Bethe Center for Theoretical Physics and Physikalisches Institut; Ramos-Sanchez, Saul [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Vaudrevange, Patrick K.S. [Muenchen Univ. (Germany). Arnold Sommerfeld Center for Theoretical Physics

    2010-07-15

    Proton hexality is a discrete symmetry that avoids the problem of too fast proton decay in the supersymmetric extension of the standard model. Unfortunately it is inconsistent with conventional grand unification. We show that proton hexality can be incorporated in the scheme of ''Local Grand Unification'' discussed in the framework of model building in (heterotic) string theory. (orig.)

  8. Proton decay: Numerical simulations confront grand unification

    International Nuclear Information System (INIS)

    Brower, R.C.; Maturana, G.; Giles, R.C.; Moriarty, K.J.M.; Samuel, S.

    1985-01-01

    The Grand Unified Theories of the electromagnetic, weak and strong interactions constitute a far reaching attempt to synthesize our knowledge of theoretical particle physics into a consistent and compelling whole. Unfortunately, many quantitative predictions of such unified theories are sensitive to the analytically intractible effects of the strong subnuclear theory (Quantum Chromodynamics or QCD). The consequence is that even ambitious experimental programs exploring weak and super-weak interaction effects often fail to give definitive theoretical tests. This paper describes large-scale calculations on a supercomputer which can help to overcome this gap between theoretical predictions and experimental results. Our focus here is on proton decay, though the methods described are useful for many weak processes. The basic algorithms for the numerical simulation of QCD are well known. We will discuss the advantages and challenges of applying these methods to weak transitions. The algorithms require a very large data base with regular data flow and are natural candidates for vectorization. Also, 32-bit floating point arithmetic is adequate. Thus they are most naturally approached using a supercomputer alone or in combination with a dedicated special purpose processor. (orig.)

  9. La Grande: volver a empezar

    Directory of Open Access Journals (Sweden)

    Julio Premat

    2011-07-01

    Full Text Available Este texto, borrador de un trabajo más amplio, pretende despejar algunas pistas de lectura de La grande, en tanto que paradójico final de la producción de Saer. Digo “paradójico” porque puede tomársela como una novela de comienzo o de origen : de un volver a empezar, en todos los sentidos del término. En esa perspectiva podrían estudiarse algunos núcleos temáticos (como el retorno o el recuerdo de cara a la construcción del texto, a la relación planteada con la tradición y a la singular historia de su escritura (y al material genético que rodea y completa esta novela a la vez inacabada y póstuma. En esta intervención, la idea es la de comentar tres textos, escenas o frases del texto, y a partir de allí esbozar pistas para un estudio que está en ciernes.Première ébauche d’un travail de plus d’ampleur, ce texte vise à éclairer quelques pistes de lecture de La grande, en tant que fin paradoxale de la production de Saer. Je dis « paradoxale » parce que l’on peut considérer cette œuvre comme un roman des commencements ou des origines : comme un retour aux débuts, dans tous les sens du terme. Dans cette perspective, plusieurs nœuds thématiques (comme le retour ou le souvenir pourraient être étudiés en relation à la construction du texte, à la relation qui s’établit avec la tradition et à la singulière histoire de son écriture (et au matériau génétique qui entoure et complète ce roman, à la fois inachevé et posthume. Il sera question ici de commenter trois textes, scènes ou phrases du texte, et d’ébaucher à partir de là quelques pistes pour une étude à l’état naissant.The objective of this text, a draft for a broader work, is to outline some reading clues for La grande, inasmuch as it constitutes a paradoxical ending of Saer’s production. I say “paradoxical” because we can consider this work a novel of beginnings or of origins: a return to the beginning, in every meaning of the

  10. Autonomous driving in urban environments: approaches, lessons and challenges.

    Science.gov (United States)

    Campbell, Mark; Egerstedt, Magnus; How, Jonathan P; Murray, Richard M

    2010-10-13

    The development of autonomous vehicles for urban driving has seen rapid progress in the past 30 years. This paper provides a summary of the current state of the art in autonomous driving in urban environments, based primarily on the experiences of the authors in the 2007 DARPA Urban Challenge (DUC). The paper briefly summarizes the approaches that different teams used in the DUC, with the goal of describing some of the challenges that the teams faced in driving in urban environments. The paper also highlights the long-term research challenges that must be overcome in order to enable autonomous driving and points to opportunities for new technologies to be applied in improving vehicle safety, exploiting intelligent road infrastructure and enabling robotic vehicles operating in human environments.

  11. GrandBase: generating actionable knowledge from Big Data

    Directory of Open Access Journals (Sweden)

    Xiu Susie Fang

    2017-08-01

    Full Text Available Purpose – This paper aims to propose a system for generating actionable knowledge from Big Data and use this system to construct a comprehensive knowledge base (KB, called GrandBase. Design/methodology/approach – In particular, this study extracts new predicates from four types of data sources, namely, Web texts, Document Object Model (DOM trees, existing KBs and query stream to augment the ontology of the existing KB (i.e. Freebase. In addition, a graph-based approach to conduct better truth discovery for multi-valued predicates is also proposed. Findings – Empirical studies demonstrate the effectiveness of the approaches presented in this study and the potential of GrandBase. The future research directions regarding GrandBase construction and extension has also been discussed. Originality/value – To revolutionize our modern society by using the wisdom of Big Data, considerable KBs have been constructed to feed the massive knowledge-driven applications with Resource Description Framework triples. The important challenges for KB construction include extracting information from large-scale, possibly conflicting and different-structured data sources (i.e. the knowledge extraction problem and reconciling the conflicts that reside in the sources (i.e. the truth discovery problem. Tremendous research efforts have been contributed on both problems. However, the existing KBs are far from being comprehensive and accurate: first, existing knowledge extraction systems retrieve data from limited types of Web sources; second, existing truth discovery approaches commonly assume each predicate has only one true value. In this paper, the focus is on the problem of generating actionable knowledge from Big Data. A system is proposed, which consists of two phases, namely, knowledge extraction and truth discovery, to construct a broader KB, called GrandBase.

  12. A Grande Reportagem no contexto informativo SIC

    OpenAIRE

    Colaço, Vanessa Alexandra Francisco

    2014-01-01

    Os telespectadores querem ver grandes reportagens? Como evoluíram as audiências da Grande Reportagem SIC? É este o produto premium da estação? Terá este formato um investimento e continuidade garantidas? Estas são algumas das questões formuladas e às quais se procurou dar resposta neste Relatório de Estágio. Neste trabalho traça-se o perfil do programa Grande Reportagem SIC, clarificando a linha editorial que lhe serviu de base, procurando perceber as suas dinâmicas e passando em revista mome...

  13. Supersymmetry and supergravity: Phenomenology and grand unification

    International Nuclear Information System (INIS)

    Arnowitt, R.; Nath, P.

    1993-01-01

    A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local supersymmetry (supergravity), grand unification, supersymmetry breaking in supergravity grand unified models, radiative breaking of SU(2) x U(1), proton decay, cosmological constraints, and predictions of supergravity grand unified models. While the number of detailed derivations are necessarily limited, a sufficient number of results are given so that a reader can get a working knowledge of this field

  14. Las cinco grandes dimensiones de la personalidad

    Directory of Open Access Journals (Sweden)

    Jan ter Laak

    1996-12-01

    Full Text Available Este artículo revisa las distintas posiciones teóricas sobre las cinco grandes dimensiones de la personalidad, mostrando las semejanzas y diferencias entre las posturas teóricas. Esta contribución presenta lo siguiente: (a la génesis del contenido y la estructura de las cinco dimensiones; (b la fortaleza de las cinco dimensiones; (e la relación de las cinco grandes dimensiones con otros constructos de personalidad; (d discute el valor predictivo de las puntuaciones del perfil de las cinco dimensiones para criterios pertinentes; (e analiza el estatus teórico de las cinco dimensiones; (f discute críticas históricas sobre las cinco grandes dimensiones y se formulan respuestas a estas críticas; (g hace conjeturas para el futuro de las cinco grandes dimensiones; y (h concluye con algunas conclusiones y comentarios.

  15. Grand unification and gravity - selected topics

    International Nuclear Information System (INIS)

    Zee, A.

    1981-09-01

    The material given here was presented in lectures delivered at the 4th Kyoto Summer Institute on Grand Unification and Related Topics. It consists of six sections. The sections are: the family problem, fermion mass hierarchy, maximal local symmetry, operator analysis of new physics, dynamically generated gravity, and Kaluza theory and grand unification. The last section contains a (hopefully) pedagogical introduction to Kaluza theory. For pedagogical completeness, several appendices reviewing some elementary notions of differential geometry have been added

  16. The Role Of The «Grand Schools» And The «Grand Corps» As Recruitment Channels For French Ministers

    Directory of Open Access Journals (Sweden)

    I. A. Zarankin

    2017-01-01

    Full Text Available The recruitment of ministers among high-ranking officials, who studied in the «grand schools» and worked in the «grand corps», is one of the typical traits of the Fifth republic. This is a consequence of the traditional interpenetration of French administrative and political elites. However, there is no common view on the actual role of these institutions in the ministers’ recruitment. So, the objective of this paper is to clarify this issue. For this purpose we analyze career trajectories of French ministers from 1981 till 2016. The data on each government include shares of ministers, who passed through the «grand schools» and the «grand corps». The article shows that nowadays the number of ministers with such an experience has decreased. Most government members are professional politicians, who have significant electoral experience and occupy high-ranking party positions. Today there are political parties, not the «grand schools» and the «grand corps», that are the main channels of the ministers’ recruitment. The professionalization of politics and reinforcement of the role of parties in the French political system are the most crucial factors of this tendency. The transformation of gaullists into liberals and conduction of the liberal economic policy, instead of the dirigist one, also contributed to replacement of officials by representatives of the private sector. Despite the fact that political parties serve as a main channel of the ministers’ recruitment, they face internal problems. The future role of political parties in the recruitment will depend on their ability to deal with these challenges.

  17. Effective Higgs theories in supersymmetric grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Sibo [Chongqing University, Department of Physics, Chongqing (China)

    2017-09-15

    The effective Higgs theories at the TeV scale in supersymmetric SU(5) grand unification models are systematically derived. Restricted to extensions on 5{sub H} containing the Higgs sector we show that only two types of real (vector-like) models and one type of chiral model are found to be consistent with perturbative grand unification. While the chiral model has been excluded by the LHC data, the fate of perturbative unification will be uniquely determined by the two classes of vector-like models. (orig.)

  18. Grand Tour: immaginario, territorio e culture digitali

    Directory of Open Access Journals (Sweden)

    Emiliano Ilardi

    2016-12-01

    Full Text Available Il Grand Tour può essere recuperato come asset narrativo utile per un intervento strategico di re-branding del viaggio in Italia? Il contributo analizza il contesto e le condizioni per una progettazione di questo livello nell’ambiente culturale dell’epoca digitale. Considerando gli archetipi moderni della mediazione dei luoghi come una grande riserva di senso, da riattivare sia nelle pratiche basate sui format seriali e transmediali che valorizzano i territori nella produzione creativa, sia nella costruzione di infrastrutture digitali e  transluoghi per la valorizzazione degli attrattori culturali.

  19. A Unified Grand Tour of Theoretical Physics

    CERN Document Server

    Lawrie, Ian D

    2002-01-01

    A unified account of the principles of theoretical physics, A Unified Grand Tour of Theoretical Physics, Second Edition stresses the inter-relationships between areas that are usually treated as independent. The profound unifying influence of geometrical ideas, the powerful formal similarities between statistical mechanics and quantum field theory, and the ubiquitous role of symmetries in determining the essential structure of physical theories are emphasized throughout.This second edition conducts a grand tour of the fundamental theories that shape our modern understanding of the physical wor

  20. Hilbert's Grand Hotel with a series twist

    Science.gov (United States)

    Wijeratne, Chanakya; Mamolo, Ami; Zazkis, Rina

    2014-08-01

    This paper presents a new twist on a familiar paradox, linking seemingly disparate ideas under one roof. Hilbert's Grand Hotel, a paradox which addresses infinite set comparisons is adapted and extended to incorporate ideas from calculus - namely infinite series. We present and resolve several variations, and invite the reader to explore his or her own variations.

  1. "Teine" võitis Prantsusmaal Grand Prix'

    Index Scriptorium Estoniae

    2006-01-01

    Prantsusmaal Essonne'is toimuval 8. Euroopa filmifestivalil Cinessonne sai üliõpilaste žürii grand prix rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre. Ka teistest festivalidest, kus film osalenud

  2. The Virtual Grand Tour as Educational Paradigm

    DEFF Research Database (Denmark)

    Hansen, Per Skafte; Mouritsen, Lars

    2001-01-01

    The Virtual Grand Tour as defined here bears some resemblance to its 18th century ancestor: a wide range of individual topics are treated as a whole; a tutor, whether real or simulated, present or remote, is provided; a set of problem solving tools forms an integrated part of the "traveller...

  3. Grand Prix Eurovision: Eine Fankultur im Medienzeitalter

    Directory of Open Access Journals (Sweden)

    Heinz Moser

    2017-06-01

    Full Text Available Der Grand Prix Eurovision ist seit Jahrzehnten eine der bekanntesten Unterhaltungssendungen im europäischen Raum. Dennoch erregte es Verwunderung, wenn der Schreibende Bekannten darüber berichtete, daß dies ein Forschungsgegenstand sei. Wurde von Interviews mit Grand Prix-Fans erzählt, so fielen schnell Aussagen wie: „Wie kann man sich nur für so etwas Abseitiges und Triviales wie den Grand Prix interessieren“. Dennoch bin ich der Meinung, daß Fankulturen für die entstehende Mediengesellschaft ein nicht unwichtiges Forschungsthema darstellen. Zwar geht es nicht um eine medienpädagogische Fragestellung im engeren Sinne; die Fans des Grand Prix Eurovision sind dem Jugendalter längst entwachsen. Dennoch handelt es sich bei Fangemeinschaften um Phänomene, die im Rahmen von Jugend- und Kinderkulturen von besonderer Relevanz sind. So meint Winter (1997, daß jugendliche Fanwelten eine bedeutende Rolle als Kristallisationspunkte kultureller Differenzierung spielen: ,Die Zugehörigkeit zu einer Fan weit ist Teil der jugendlichen Lebensbewältigung in der Postmoderne, denn in der Gemeinschaft der Fans können Jugendliche emotionale Allianzen eingehen, außeralltäglichen Beschäftigungen nachgehen, expressive Identitätsmuster gemeinschaftlich realisieren und sich mit ihrer Lebenssituation als Heranwachsende auseinandersetzen“ (Winter 1997, S. 51f..

  4. Grand Canyon Monitoring and Research Center

    Science.gov (United States)

    Hamill, John F.

    2009-01-01

    The Grand Canyon of the Colorado River, one of the world's most spectacular gorges, is a premier U.S. National Park and a World Heritage Site. The canyon supports a diverse array of distinctive plants and animals and contains cultural resources significant to the region's Native Americans. About 15 miles upstream of Grand Canyon National Park sits Glen Canyon Dam, completed in 1963, which created Lake Powell. The dam provides hydroelectric power for 200 wholesale customers in six western States, but it has also altered the Colorado River's flow, temperature, and sediment-carrying capacity. Over time this has resulted in beach erosion, invasion and expansion of nonnative species, and losses of native fish. Public concern about the effects of Glen Canyon Dam operations prompted the passage of the Grand Canyon Protection Act of 1992, which directs the Secretary of the Interior to operate the dam 'to protect, mitigate adverse impacts to, and improve values for which Grand Canyon National Park and Glen Canyon National Recreation Area were established...' This legislation also required the creation of a long-term monitoring and research program to provide information that could inform decisions related to dam operations and protection of downstream resources.

  5. Comprehensive District Reform: Philadelphia's Grand Experiment.

    Science.gov (United States)

    Useem, Elizabeth; Balfanz, Robert

    2002-01-01

    This report describes "Philadelphia's Grand Experiment" in comprehensive school district reform, from its conception through its initial months of implementation. In 2001, as part of the remedy for low student performance, the governor ordered the state to take over governance of the Philadelphia School District, with a substantial…

  6. Rio Branco, grand strategy and naval power

    Directory of Open Access Journals (Sweden)

    João Paulo Alsina Jr.

    2014-12-01

    Full Text Available This article addresses Baron of Rio Branco's grand strategy and the role played by the naval reorganization program (1904-1910 in this context. The ensuing case study determined the domestic and international constraints that affected the program, as well as the worldview of the patron of Brazilian diplomacy regarding military power's instrumentality to foreign policy.

  7. Reisipakkumine - Grand Tour Itaalias / Mai Levin

    Index Scriptorium Estoniae

    Levin, Mai, 1942-

    2009-01-01

    Tiina Abeli koostatud ja Urmas Viigi kujundatud näitus "Grand Tour. Eesti kunstnikud Itaalias" Kumu Kunstimuuseumis 05. aprillini. Loetletud eksponeeritud tööde autoreid. Näitus annab ülevaate, kes siinsetest kunstnikest 19. sajandi algusest kuni 1930ndate aastateni Itaalias käisid ja kuidas see nende loomingut mõjutas

  8. Middle Rio Grande Basin Research Report 2008

    Science.gov (United States)

    Deborah M. Finch; Catherine Dold

    2008-01-01

    An ecosystem is rarely static. A natural system composed of plants, animals, and microorganisms interacting with an area's physical factors, an ecosystem is always fluctuating and evolving. But sometimes, often at the hands of humans, ecosystems change too much. Such is the case with many of the ecosystems of the Middle Rio Grande Basin of New Mexico.

  9. Panel - Rio Grande restoration: Future directions

    Science.gov (United States)

    Deborah M. Finch; Pete V. Domenici; Jeffrey. C. Whitney; Steve Harris; Brian Shields; Clifford S. Crawford

    1996-01-01

    The purpose of this panel was to discuss historical and current changes to the Rio Grande system, focusing on the middle Basin, and to present and review different individual, organizational, and political perspectives on the future of the system. Invitations were made to panelists based on their past and current interests and activities pertaining to restoration of...

  10. GRANDES PROJETOS NA AMAZÔNIA: MUDANÇAS E PERSPECTIVAS NA PRODUÇÃO DO ESPAÇO URBANO EM IRANDUBA – AM (Great projects in the Amazon: challenges and prospects in the production of urban space in Iranduba – AM)

    OpenAIRE

    SOUSA, Isaque dos Santos

    2011-01-01

    Neste artigo discute-se algumas das recentes transformações observadas na cidade de Iranduba-AM influenciada por dois grandes projetos de infraestrutura: o gasoduto Coari-Manaus e a ponte sobre o rio Negro. As análises postas são feitas com base na observação direta em campo, na coleta de dados em bancos oficiais como o do Sistema Único de Saúde – Datasus e o Instituto Brasileiro de Geografia e Estatística – IBGE. Dentre as principais mudanças na cidade em estudo, destacam-se o crescimento da...

  11. The Grand Ethiopian Renaissance Dam: Source of cooperation or contention?

    Science.gov (United States)

    Teferi Taye, Meron; Tadesse, Tsegaye; Senay, Gabriel; Block, Paul

    2016-01-01

    This paper discusses the challenges and benefits of the Grand Ethiopian Renaissance Dam (GERD), which is under construction and expected to be operational on the Blue Nile River in Ethiopia in a few years. Like many large-scale projects on transboundary rivers, the GERD has been criticized for potentially jeopardizing downstream water security and livelihoods through upstream unilateral decision making. In spite of the contentious nature of the project, the authors argue that this project can provide substantial benefits for regional development. The GERD, like any major river infrastructure project, will undeniably bring about social, environmental, and economic change, and in this unique case has, on balance, the potential to achieve success on all fronts. It must be stressed, however, that strong partnerships between riparian countries are essential. National success is contingent on regional cooperation.

  12. Managing complexity practical considerations in the development and application of ABMs to contemporary policy challenges

    CERN Document Server

    O’Brien, Sean; Khouja, Moutaz

    2013-01-01

    This book emerged out of a project initiated and funded by the Defense Advanced Research Projects Agency (DARPA) that sought to build on efforts to transform agent-based models into platforms for predicting and evaluating policy responses to real world challenges around the world.  It began with the observation that social science theories of human behavior are often used to estimate the consequences of alternative policy responses to important issues and challenges.  However, alternative theories that remain subject to contradictory claims are ill suited to inform policy. The vision behind the DARPA project was to mine the social sciences literature for alternative theories of human behavior, and then formalize, instantiate, and integrate them within the context of an agent-based modeling system.  The research team developed an experimental platform to evaluate the conditions under which alternative theories and groups of theories applied.  The end result was a proof of concept—developed from the groun...

  13. Cosmological implications of grand unified theories

    International Nuclear Information System (INIS)

    Nanopoulos, D.V.

    1982-01-01

    These lectures, mainly devoted to the cosmological implications of GUTs, also include the essential ingredients of GUTs and some of their important applications to particle physics. Section 1 contains some basic points concerning the structure of the standard strong and electroweak interactions prior to grand unification. A detailed expose of GUTs is attempted in sect. 2, including their basci principles and their consequences for particle physics. The minimal, simplest GUT, SU 5 is analysed in some detail and it will be used throughout these lectures as the GUT prototype. Finally, sect. 3 contains the most important cosmological implications of GUTs, including baryon number generation in the early Universe (in rather lengthy detail), dissipative processes in the very early Universe, grand unified monopoles, etc. (orig./HSI)

  14. The geology of Piz Pian Grand

    International Nuclear Information System (INIS)

    Huber, M.; Staeuble, J.

    1987-01-01

    Nagra has identified four potential sites for a repository for low- and intermediate-level waste. Exploration work is already underway at Oberbauenstock (UR) and Piz Pian Grand (GR). As part of the investigations in the Piz Pian Grand area, geological surface mapping was carried out between 1984 and 1987. Since the data obtained is still being evaluated, it would be premature to draw any interpretative conclusions at this stage. On the other hand, some of the most significant observations of this work can be summarised here. As a first step, the geological framework in which these investigations are to be seen should be defined. Observations will then be made on the rock content (lithology) and geometric structure (structural geology) of the area. (author) 6 figs

  15. Fabrication challenges associated with conformal optics

    Science.gov (United States)

    Schaefer, John; Eichholtz, Richard A.; Sulzbach, Frank C.

    2001-09-01

    A conformal optic is typically an optical window that conforms smoothly to the external shape of a system platform to improve aerodynamics. Conformal optics can be on-axis, such as an ogive missile dome, or off-axis, such as in a free form airplane wing. A common example of conformal optics is the automotive head light window that conforms to the body of the car aerodynamics and aesthetics. The unusual shape of conformal optics creates tremendous challenges for design, manufacturing, and testing. This paper will discuss fabrication methods that have been successfully demonstrated to produce conformal missile domes and associated wavefront corrector elements. It will identify challenges foreseen with more complex free-form configurations. Work presented in this paper was directed by the Precision Conformal Optics Consortium (PCOT). PCOT is comprised of both industrial and academic members who teamed to develop and demonstrate conformal optical systems suitable for insertion into future military programs. The consortium was funded under DARPA agreement number MDA972-96-9-08000.

  16. Grand Gulf-prioritization of regulatory requirements

    International Nuclear Information System (INIS)

    Meisner, M.J.

    1993-01-01

    As cost pressures mount, Grand Gulf nuclear station (GGNS) is relying increasingly on various prioritization approaches to implement, modify, eliminate, or defer regulatory requirements. Regulatory requirements can be prioritized through the use of three measures: (1) safety (or risk) significance; (2) cost; and (3) public policy (or political) significance. This paper summarizes GGNS' efforts to implement solutions to regulatory issues using these three prioritization schemes to preserve a balance between cost and safety benefit

  17. Between two evils: Investors prefer grand corruption!

    OpenAIRE

    Graf Lambsdorff, Johann

    2005-01-01

    Recent empirical studies claim that, in addition to levels of corruption, investors are deterred by its unpredictability. I claim instead that it is petty corruption that deters investors. I employ seven subcomponents of corruption for a sample of 102 countries that appear in the 2003 Global Competitiveness Report of the WEF. The second principal component of this data depicts a grand, political type, embracing corruption in government policymaking and in judicial decisions as opposed to corr...

  18. Meliponiculture in Rio Grande do Norte

    Directory of Open Access Journals (Sweden)

    Ulysses Madureira Maia

    2015-12-01

    Full Text Available ABSTRACT. Maia U.M., Jaffe R., Carvalho A.T. & Imperatriz-Fonseca V.L. [Meliponiculture in Rio Grande do Norte.] Meliponicultura no Rio Grande do Norte. Revista Brasileira de Medicina Veterinária, 37(4:327-333, 2015. Departamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, SP 14040-901, Brasil. E-mail: ummaia@usp.br This study aimed to assess the current status of stingless bee beekeeping (meliponiculture in the State of Rio Grande do Norte, Brazil, with the aid of structured questionnaires made during visits to beekeepers. The results were compared with a previous census made in the state and with a similar study from Australia. Meliponiculture in Rio Grande do Norte is still informal and little standardized. The activity has grown in recent years considering the mean number of nests per beekeeper. Most apiaries are formed of up to 50 colonies, usually distributed in the backyards of homes. Twelve species of stingless bees were reared in the state, and the most common was the “Jandaíra” bee (Melipona subnitida, whose honey is considered medicinal. While many beekeepers already know the importance of bees as pollinators, stingless bees are still not used for crop pollination. Compared to a recent analysis of beekeeping in Australia, meliponiculture in Brazil is more traditional, honey is the main product and the number of colonies per beekeeper is much higher. Our results highlight the need to reinforce knowledge about bees and promote specific training aimed at improving and standardizing management practices.

  19. Neutrino mixing in a grand unified theory

    International Nuclear Information System (INIS)

    Milton, K.; Tanaka, K.

    1980-01-01

    Neutrino mixing in a grand unified theory in which the neutrino mass matrix is determined by the Gell-Mann-Ramond-Slansky mechanism was investigated. With an arbitrary real right-handed Majorana mass matrix which incorporates three neutrino mass scales, the effects of the up-quark mass matrix are found to be dominant and as a result no significant mixing of ν/sub e/ occurs, while ν/sub μ/ - ν/sub γ/ mixing can be substantial

  20. The Grand Strategy of Charles de Gaulle

    Science.gov (United States)

    1989-09-08

    4. TITLE AND SUBTITLE The Grand Startegy of Charles de Gaulle 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...dependent on French influence within NATO and the Common Market . De Gaulle frequently used these fora to veto British and American initiatives. As Cook...the reserve currency. Gold would be the basis of international finance and a French-dominated European Common Market would provide the framework

  1. [Grand Banks activity : updates and opportunities

    International Nuclear Information System (INIS)

    Bruce, G.

    1998-01-01

    An overview of the exploration and on-going activities by the petroleum industry on the Grand Banks of Newfoundland was presented. The two offshore oil developments underway are Hibernia and Terra Nova, both located in the Jeanne d'Arc Basin. Current production from Hibernia is 68,000 bopd, expected to rise to 130,000 bopd in 1999. The Terra Nova Field is still under development. Total recoverable reserves from the 17 discoveries made in the Jeanne d'Arc Basin are estimated at 1.6 billion barrels of oil and 4 trillion cubic feet of gas. Industry participants in the area include Amoco, Petro-Canada, Mobil, Chevron, Husky and Norsk Hydro. Petro-Canada believes the Grand Banks represent one of the best opportunities for oil anywhere in the world. There are currently 21 exploration licenses held on the Grand Banks. Major attractions of the area include the large reserve potential, the relatively low finding costs, the size of the pools being discovered, improvements in offshore technology that have substantially lowered development costs, and a profit-sensitive generic royalty regime that ensures reasonable rates of return for investors. figs

  2. Proton decay in grand unified theories

    International Nuclear Information System (INIS)

    Lucha, W.

    1984-01-01

    Interactions which violate the conservation of baryon and lepton number represent an intrinsic part of all grand unified theories (GUTs) of strong and electroweak interactions. These new interactions - predicted within the framework of GUTs - generate B and L violating four-fermion interactions via the exchange of superheavy particles which cannot be ascribed a well-defined baryon or lepton number. The effective coupling constant of these four-fermion interactions might be large enough to make the proton decay detectable by the present generation of experiments. In this review the basic concepts of conventional as well as supersymmetric GUTs relevant for proton decay are sketched. The baryon number violating sector of grand unified theories is discussed in more detail. Special emphasis is laid on the various selection rules arising as consequences of low-energy gauge invariance and supersymmetry for proton decay. These selection rules already determine the coarse pattern of the resulting decay modes and branching ratios without any reference to or detailed knowledge of the underlying grand unified theory. Finally the numerous theoretical predictions are summarized and confronted with experiment. (Author)

  3. Raptor Use of the Rio Grande Gorge

    Energy Technology Data Exchange (ETDEWEB)

    Ponton, David A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-20

    The Rio Grande Gorge is a 115 km long river canyon located in Southern Colorado (15 km) and Northern New Mexico (100 km). The majority of the canyon is under the administration of the Bureau of Land Management {BLM), and 77 km of the canyon south of the Colorado/New Mexico border are designated Wild River under the National Wild and Scenic Rivers Act of 1968. Visits I have made to the Rio Grande Gorge over the past 15 .years disclosed some raptor utilization. As the Snake River Birds of Prey Natural Area gained publicity, its similarity to the Rio Grande Gorge became obvious, and I was intrigued by the possibility of a high raptor nesting density in the Gorge. A survey in 1979 of 20 km of the northern end of the canyon revealed a moderately high density of red-tailed hawks and prairie falcons. With the encouragement of that partial survey, and a need to assess the impact of river-running on nesting birds of prey, I made a more comprehensive survey in 1980. The results of my surveys, along with those of a 1978 helicopter survey by the BLM, are presented in this report, as well as general characterization of the area, winter use by raptors, and an assessment of factors influencing the raptor population.

  4. DARPA Status Report - November 1988

    Science.gov (United States)

    1988-11-01

    equilibrium the absolute coe function no longer changes, this mom fine optimiaion. This allows a tradeoff berka implies thax the expected value of the...the trace, simply that the author of PERO bad made an explicit deci- where vs is the numbe of processors. In other words, the Limes sion not to use...The positive portion of P (AC) must either shift right (greater bad moves) or up (more bad moves), k- - "𔃼asing the expected positive component of AC

  5. Gradient Index Optics at DARPA

    Science.gov (United States)

    2013-11-01

    for correcting vision. René Descartes proposed another idea to cor- rect vision in 1636: use a glass tube filled with liquid and place it in direct... Descartes published the present form of this law, a basis of modern geometric optics known as Snell’s Law (Fishman 2000, 405, 408) (see Figure 1-6). At

  6. LEP constraints on grand unified theories

    International Nuclear Information System (INIS)

    Sarkar, Utpal

    1993-01-01

    Recent developments on grand unified theories (GUTs) in the context of the LEP measurements of the coupling constants are reviewed. The three coupling constants at the electroweak scale have been measured at LEP quite precisely. One can allow these couplings to evolve with energy following the renormalization group equations for the various groups and find out whether all the coupling constants meet at any energy. It was pointed out that the minimal SU(5) grand unified theory fails to satisfy this test. However, various extensions of the theory are still allowed. These extensions include (i) supersymmetric SU(5) GUT, with some arbitrariness in the susy breaking scale arising from the threshold corrections, (ii) non-susy SU(5) GUTs with additional fermions as well as Higgs multiplets, which has masses of the order of TeV, and (iii) non-renormalizable effect of gravity with a fine tuned relation among the coupling constants at the unification energy. The LEP results also constrain GUTs with an intermediate symmetry breaking scale. By adjusting the intermediate symmetry breaking scale, one usually can have unification, but these theories get constrained. For example, the left-right symmetric theories coming from GUTs can be broken only at energies higher than about ∼10 10 GeV. This implies that if right handed gauge bosons are found at energies lower than this scale, then that will rule out the possibility of grand unification. Another recent interesting development on the subject, namely, low energy unification, is discussed in this context. All the coupling constants are unified at energies of the order of ∼10 8 GeV when they are embedded in an SU(15)GUT, with some particular symmetry breaking pattern. But even in this case the results of the intermediate symmetry breaking scale remain unchanged. (author). 16 refs., 3 figs

  7. Maternal and fetal outcome in grand multipara

    International Nuclear Information System (INIS)

    Qamar, A.; Qamar, S.

    2015-01-01

    Study Design: Case control study. Place and Duration of Study: Gynecology and Obstetric Unit-I of the Jinnah Post Graduate and Medical Centre Karachi, from February 2009 to January 2010. Patients and Methods: One hundred (100) patients of grand multipara (GMP), (parity = 5) and 100 patients of multipara (MP) (parity 2-4) were included in the study. Pregnant women with known medical conditions including essential hypertension, diabetes mellitus, epilepsy, primigravidas, women with previous caesarean section and twin pregnancies were excluded. Patients were admitted through antenatal clinic and emergency. A detailed history was taken and a physical examination was done with special emphasis on obstetrical examination. Investigations like blood CP, Urine D/R, blood grouping and sonogram were done. During labour, mother and neonates were managed according to ward protocols. Maternal and fetal outcomes were compared among GMPs and MPs. Results: A high frequency of anaemia (81% vs 20%), pregnancy induced hypertension (45%, vs. 26%) and gestational diabetes (9%, vs1%) were seen in GMP as compared to MP group. Frequency of malpresentations (26% vs 15%), postpartum hemorrhage (15%, vs 10%) and intrauterine deaths (26%, vs 13%) were higher in GMP group along with a high caesarean delivery rate (GMP 21%, MP 14%). A higher maternal mortality (GMP 4%, MP 1%) and low APGAR score (GMP 12%, MP 4%) were observed among babies born to grand multipara group. Conclusion: Grand multiparity is associated with adverse outcome for both mother and fetus. Effort should be directed to reduce high parity in the community through effective family planning initiatives. Specialized antenatal and obstetrical care facilities should be available. (author)

  8. Applying Systems Engineering on Energy Challenges

    NARCIS (Netherlands)

    Safi, J.; Muller, G.; Bonnema, Gerrit Maarten

    2012-01-01

    Systems engineering is a discipline with methods and techniques to address complex problems. We want to study how Systems Engineering methods can help to address today's grand challenges, such as the energy problem. The first step is problem definition which aims at articulating the problem in its

  9. Lie groups and grand unified theories

    International Nuclear Information System (INIS)

    Gubitoso, M.D.

    1987-01-01

    This work presents some concepts in group theory and Lie algebras and, at same time, shows a method to study and work with semisimple Lie groups, based on Dynkin diagrams. The aproach taken is not completely formal, but it presents the main points of the elaboration of the method, so its mathematical basis is designed with the purpose of making the reading not so cumbersome to those who are interested only in a general picture of the method and its usefulness. At the end it is shown a brief review of gauge theories and two grand-unification models based on SO(13) and E 7 gauge groups. (author) [pt

  10. Grand Canonical Ensembles in General Relativity

    International Nuclear Information System (INIS)

    Klein, David; Yang, Wei-Shih

    2012-01-01

    We develop a formalism for general relativistic, grand canonical ensembles in space-times with timelike Killing fields. Using that, we derive ideal gas laws, and show how they depend on the geometry of the particular space-times. A systematic method for calculating Newtonian limits is given for a class of these space-times, which is illustrated for Kerr space-time. In addition, we prove uniqueness of the infinite volume Gibbs measure, and absence of phase transitions for a class of interaction potentials in anti-de Sitter space.

  11. Produccion de plantas grandes usando minicontenedores

    Science.gov (United States)

    R. Kasten Dumroese; Thomas D. Landis

    2012-01-01

    En América del Norte hay cada vez más interés por la producción híbrida o mixta. La misma consiste en cultivar plantines en contenedores de pequeño volumen y luego trasplantarlos; el trasplante se puede realizar a canteros en el suelo como en la producción a raíz desnuda o bien a contenedores más grandes. Originalmente se llamaban plantines "plug+", "...

  12. The Grand Duchy on the Grand Tour: A Historical Study of Student Migration in Luxembourg

    Science.gov (United States)

    Rohstock, Anne; Schreiber, Catherina

    2013-01-01

    Since Luxembourg became independent in 1839, practically the entire political, economic and intellectual elite of the country has been socialised abroad. It was only in 2003 that the Grand Duchy set up its own university; before then, young Luxembourgers had to study in foreign countries. Over the past 150 years, Luxembourg has thus experienced…

  13. 28 milliards d’euros, c’est grand comment ?

    OpenAIRE

    Ozer, Pierre; Salmon, Marc; Theunissen, Yannick

    2009-01-01

    J’ouvre mon quotidien. Fortis : 28 milliards d’euros de pertes en 2008. Ma fille de sept ans qui commence à lire et pose sans cesse des questions sur tout me lance : « Dis-moi, papa : 28 milliards d’euros, c’est grand comment ? ». Grande question… Je réfléchis et tente de trouver une parade parlante pour un enfant qui, in fine, se pose les mêmes questions que les grandes personnes.

  14. Gamma ray and neutrino detector facility (GRANDE), Task C

    International Nuclear Information System (INIS)

    Sobel, H.W.; Yodh, G.B.

    1991-08-01

    GRANDE is an imaging, water Cerenkov detector, which combines in one facility an extensive air shower array and a high-energy neutrino detector. We proposed that the detector be constructed in phases, beginning with an active detector area of 31,000 m 2 (GRANDE-I) 2 and expanding to a final size of 100,000--150,00 m 2 . Some of the characteristics of GRANDE-I are discussed in this paper

  15. O conservadorismo patronal da grande imprensa brasileira

    Directory of Open Access Journals (Sweden)

    Fonseca Francisco

    2003-01-01

    Full Text Available Através da análise da opinião dos editoriais dos quatro principais periódicos diários da grande imprensa, isto é, o Jornal do Brasil, O Globo, a Folha de S. Paulo e O Estado de S. Paulo - aqui considerados "aparelhos privados de hegemonia" -, este artigo procura desvendar os posicionamentos adotados perante a ordem social na Constituinte de 1987/1988, que também contribuem para compreender a reação à Consolidação das Leis do Trabalho. Observa-se, além do mais, as estratégias utilizadas para sua consecução. Conclui-se que, por mecanismos diversos, a grande imprensa contribuiu decisivamente para a introdução da agenda ideológica neoliberal no país, pois atuou de forma a "divulgar e vulgarizar" as idéias pertinentes a este ideário e de forma militantemente conservadora e patronal.

  16. Aprovechamiento de Salto Grande Argentina – Uruguay

    Directory of Open Access Journals (Sweden)

    Bongiovanni, M.

    1979-12-01

    Full Text Available The power harnessing of Salto Grande will be the first common project carried out by two South American Countries and this will foster greater integration of both countries. The project involves the following: — One 39 m-high dam — Two hydroelectric power plants — One international bridge — One shipping canal The benefits to be obtained from the project include: increase and improvement of the waterway network; increase of electricity production; railways and highway tie-ups between both countries; industrial development; increased availability of irrigation water; new tourist resorts; increase of fishing resources.

    El aprovechamiento hidroeléctrico de Salto Grande será el primer aprovechamiento común a dos países sudamericanos, lo que permitirá una mayor integración entre ellos. Consta de las siguientes obras: _ una presa de 39 m de altura; _ dos centrales hidroeléctricas; _ un puente internacional; _ un canal de navegación, etc. Entre los beneficios que se obtendrán destacan: aumento y mejora de la red de navegación; aumento de la producción eléctrica; enlace de las vías de ferrocarril y carreteras entre los dos países; desarrollo industrial; aumento de la disponibilidad de agua de riego; creación de zonas de turismo, e incremento de la riqueza piscícola.

  17. Estimating large complex projects Estimando proyectos grandes y complejos

    Directory of Open Access Journals (Sweden)

    Cliff Schexnayder

    2007-08-01

    Full Text Available Managing large capital construction projects requires the coordination of a multitude of human, organizational, technical, and natural resources. Quite often, the engineering and construction complexities of such projects are overshadowed by economic, societal, and political challenges. The ramifications and effects, which result from differences between early project cost estimates and the bid price or the final project cost, are significant. Over the time span between the initiation of a project and the completion of construction many factors influence a project's final costs. This time span is normally several years in duration but for highly complex and technologically challenging projects, project duration can easily exceed a decade. Over that period, changes to the project scope often occur. The subject here is a presentation of strategies that support realistic cost estimating. Through literature review and interviews with transportation agencies in the U.S. and internationally the authors developed a database of the factors that are the root causes of cost estimation problemsGestionar proyectos de construcción de grandes capitales requiere de la coordinación de una multitud de recursos humanos, organizacionales, técnicos y naturales. Frecuentemente, las complejidades del diseño y construcción de esos grandes proyectos son tapadas por sus desafíos económicos, políticos y sociales. Las ramificaciones y efectos que resultan de las diferencias entre la estimación de costo inicial, el costo de la propuesta adjudicada y el costo final del proyecto son significativas. Hay numerosos factores que inciden en el costo final del proyecto entre su inicio y finalización. La duración es generalmente de varios años y puede incluso superar la década para aquellos especialmente complejos y desafiantes. En ese período de tiempo, cambios en los alcances del proyecto cambian frecuentemente. El tópico del presente artículo es mostrar

  18. La masa de los grandes impactores

    Science.gov (United States)

    Parisi, M. G.; Brunini, A.

    Los planetas han sido formados fundamentalmente acretando masa a través de colisiones con planetesimales sólidos. La masa más grande de la distribución de planetesimales y las masas máxima y mínima de los impactores, han sido calculadas usando los valores actuales del período y de la inclinación de los planetas (Lissauer & Safronov 1991; Parisi & Brunini 1996). Recientes investigaciones han mostrado, que las órbitas de los planetas gigantes no han sufrido variaciones con el tiempo, siendo su movimiento regular durante su evolución a partir de la finalización de la etapa de acreción (Laskar 1990, 1994). Por lo tanto, la eccentricidad actual de los planetas gigantes se puede utilizar para imponer una cota máxima a las masas y velocidades orbitales de los grandes impactores. Mediante un simple modelo dinámico, y considerando lo arriba mencionado, obtenemos la cota superior para la masa del planetesimal más grande que impactó a cada planeta gigante al final de su etapa de acreción. El resultado más importante de este trabajo es la estimación de la masa máxima permitida para impactar a Júpiter, la cúal es ~ 1.136 × 10 -1, siendo en el caso de Neptuno ~ 3.99 × 10 -2 (expresada en unidades de la masa final de cada planeta). Además, fue posible obtener la velocidad orbital máxima permitida para los impactores como una función de su masa, para cada planeta. Las cotas obtenidas para la masa y velocidad de los impactores de Saturno y Urano (en unidades de la masa y velocidad final de cada planeta respectivamente) son casi las mismas que las obtenidas para Júpiter debido a que estos tres planetas poseen similar eccentricidad actual. Nuestros resultados están en buen acuerdo con los obtenidos por Lissauer & Safronov (1991). Estas cotas podrían ser utilizadas para obtener la distribución de planetesimales en el Sistema Solar primitivo.

  19. Local grand unification and string theory

    International Nuclear Information System (INIS)

    Nilles, Hans Peter; Vaudrevange, Patrick K.S.

    2009-09-01

    The low energy effective action of string theory depends strongly on the process of compactification and the localization of fields in extra dimensions. Explicit string constructions towards the minimal supersymmetric standard model (MSSM) reveal interesting results leading to the concept of local grand unification. Properties of the MSSM indicate that we might live at a special location close to an orbifold fixed point rather than a generic point in Calabi-Yau moduli space. We observe an enhancement of (discrete) symmetries that have various implications for the properties of the MSSM such as proton stability as well as solutions to the flavor problem, the m-problem and the strong CP-problem. (orig.)

  20. A unified grand tour of theoretical physics

    CERN Document Server

    Lawrie, Ian D

    2013-01-01

    A Unified Grand Tour of Theoretical Physics invites its readers to a guided exploration of the theoretical ideas that shape our contemporary understanding of the physical world at the fundamental level. Its central themes, comprising space-time geometry and the general relativistic account of gravity, quantum field theory and the gauge theories of fundamental forces, and statistical mechanics and the theory of phase transitions, are developed in explicit mathematical detail, with an emphasis on conceptual understanding. Straightforward treatments of the standard models of particle physics and cosmology are supplemented with introductory accounts of more speculative theories, including supersymmetry and string theory. This third edition of the Tour includes a new chapter on quantum gravity, focusing on the approach known as Loop Quantum Gravity, while new sections provide extended discussions of topics that have become prominent in recent years, such as the Higgs boson, massive neutrinos, cosmological perturba...

  1. Introduction to Grand Unified Theories. 12

    International Nuclear Information System (INIS)

    Wali, K.C.

    1989-01-01

    This chapter presents an introduction into Grand Unified Theories. After a discussion of the general features to be expected in any such theory, and of the motivations for them, a detailed presentation of SU(5) theory is given. The group structures, particle multiplets, gauge and Higgs bosons are explained. The two stages of spontaneous symmetry breaking via the Higgs model, are calculated individually and in combination. Fermion mass matrices and relations between quark and lepton masses are derived. predictions of SU(5) theory, calculated using renormalization group methods, are derived. The chapter ends with discussions that bring together particle physics and cosmology, including the baryon asymmetry problem, phase transitions in the very early universe, and singularities like domain walls, vortex lines and monopoles. (author). 9 refs.; 4 figs.; 5 tabs

  2. Supersymmetric grand unified theories and cosmology

    International Nuclear Information System (INIS)

    Lazarides, G.; Shafi, Q.

    1983-01-01

    By examining the behavior of supersymmetric grand unified theories (GUT's) in the very early universe we find two classes of realistic models. In one of them supersymmetry is broken at or near superheavy GUT scale. The cosmological implications of such models are expected to be similar to those of nonsupersymmetric GUT's. In the second class of models, the superheavy GUT scale is related to the supersymmetry-breaking scale in the manner of Witten. Two types of cosmological scenarios appear possible in this case, either with or without an intermediate (new) inflationary phase. They can be experimentally distinguished, since the former predicts an absence and the latter an observable number density of superheavy monopoles. A mechanism for generating baryon asymmetry in such models is pointed out

  3. Pitié pour les grandes villes !

    Directory of Open Access Journals (Sweden)

    Jérôme Monnet

    1997-02-01

    Full Text Available Roger Caillois disait, en 1938, qu´il existe "une représentation de la grande ville, assez puissante sur les imaginations pour que jamais en pratique ne soit posée la question de son exactitude, créée de toute pièce par le livre, assez répandue néanmoins pour faire partie de l´atmosphère mentale collective et posséder par suite une certaine force de contrainte"(Le mythe et l´homme, p.156 [c´est lui qui souligne]. En 1996, la presse française a consacré dossiers et articles à "Habitat II...

  4. Preface to a GUT (Grand Unified Theory)

    International Nuclear Information System (INIS)

    Honig, W.

    1982-01-01

    A Grand Unified Theory (GUT) is proposed exhibiting relativistic invariance and based on a physical model for vacuum space consisting of the superposition of oppositely charged continuous fluids. Models for the photon, electron, neutrino, proton, etc., consist of separate unique variations in the relative densities of the fluids and their flow patterns. This GUT is also based on the use of transfinite axiomatic number forms and on a concept of metrical relativity which hopefully reconciles the many logical dichotomies in and between Special Relativity and Quantum Mechanics. These ideas result in a number of experimental proposals and predicted results which appear to be underivable from present paradigms, first among which is a physical model for the hidden variable of Quantum Mechanics. It is on these features that attention should rest. (Auth.)

  5. Higgsless grand unified theory breaking and trinification

    International Nuclear Information System (INIS)

    Carone, Christopher D.; Conroy, Justin M.

    2004-01-01

    Boundary conditions on an extra dimensional interval can be chosen to break bulk gauge symmetries and to reduce the rank of the gauge group. We consider this mechanism in models with gauge trinification. We determine the boundary conditions necessary to break the trinified gauge group directly down to that of the standard model. Working in an effective theory for the gauge-symmetry-breaking parameters on a boundary, we examine the limit in which the grand-unified theory-breaking-sector is Higgsless and show how one may obtain the low-energy particle content of the minimal supersymmetric standard model. We find that gauge unification is preserved in this scenario, and that the differential gauge coupling running is logarithmic above the scale of compactification. We compare the phenomenology of our model to that of four dimensional 'trinified' theories

  6. Grand unified models including extra Z bosons

    International Nuclear Information System (INIS)

    Li Tiezhong

    1989-01-01

    The grand unified theories (GUT) of the simple Lie groups including extra Z bosons are discussed. Under authors's hypothesis there are only SU 5+m SO 6+4n and E 6 groups. The general discussion of SU 5+m is given, then the SU 6 and SU 7 are considered. In SU 6 the 15+6 * +6 * fermion representations are used, which are not same as others in fermion content, Yukawa coupling and broken scales. A conception of clans of particles, which are not families, is suggested. These clans consist of extra Z bosons and the corresponding fermions of the scale. The all of fermions in the clans are down quarks except for the standard model which consists of Z bosons and 15 fermions, therefore, the spectrum of the hadrons which are composed of these down quarks are different from hadrons at present

  7. Review of freeboard: Grand Rapids Generating Station

    Energy Technology Data Exchange (ETDEWEB)

    Groeneveld, J.L.; Harding, W.B.; Bonin, D.V.; Fuchs, D.M. [Acres Manitoba Ltd., Winnipeg, MB (Canada); Warner, B.J. [Manitoba Hydro, Winnipeg, MB (Canada)

    2001-10-01

    Constructed during the period 1960-1965, the Grand Rapids Generating Station is a 472 MW hydroelectric station located approximately 400 kilometres northwest of Winnipeg, Manitoba, on the Saskatchewan River. An intake structure, four penstocks, a four-unit plus house unit powerhouse, wing walls, extensive dyke structures and a four-bay spillway are the components of the generating station. A little over ten years ago, the Manitoba Hydro Dam Safety Program was initiated. The program included a detailed dam safety review of the Grand rapids Generating Station. A potential deficiency in the freeboard allowance for several of the earthen dykes was revealed by the review process. The dam safety guidelines sponsored by the Canadian Dam Association were not met. The occurrence of a 1:1000 year wind event from the critical direction when the reservoir was at or near its full supply level was compounded by the analysis. The establishment of a wind and wave monitoring program was included in the deficiency studies commissioned. The objective was to confirm the empirical estimates concerning wave height, the development and usage of a two dimensional numerical wave model, and additional freeboard analyses to refine estimates of the recurrence interval of the current level of protection. A statistical Monte Carlo analysis was performed in the case of the estimates of the recurrence interval to determine the joint probabilities of seasonal variations in wind direction, wind speed, and reservoir level. The estimate of the actual risk of overtopping was therefore refined, and the details pertaining to the methodology and the conclusions of the analysis are all included in the paper. 15 refs., 4 tabs., 9 figs.

  8. Perspective view over the Grand Canyon, Arizona

    Science.gov (United States)

    2001-01-01

    This simulated true color perspective view over the Grand Canyon was created from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) data acquired on May 12, 2000. The Grand Canyon Village is in the lower foreground; the Bright Angel Trail crosses the Tonto Platform, before dropping down to the Colorado Village and then to the Phantom Ranch (green area across the river). Bright Angel Canyon and the North Rim dominate the view. At the top center of the image the dark blue area with light blue haze is an active forest fire. ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate. Size: 5 km in foreground to 40 km Location: 36.3 degrees north latitude, 112 degrees west longitude Orientation: North-northeast at top Original Data Resolution: ASTER 15 meters Dates Acquired: May 12, 2000

  9. Cognitive Challenges

    Science.gov (United States)

    ... Privacy Policy Sitemap Learn Engage Donate About TSC Cognitive Challenges Approximately 45% to 60% of individuals with TSC develop cognitive challenges (intellectual disabilities), although the degree of intellectual ...

  10. Phase transitions at finite chemical potential in grand unified theories

    International Nuclear Information System (INIS)

    Bailin, D.; Love, A.

    1984-01-01

    We discuss the circumstances in which non-zero chemical potentials might prevent symmetry restoration in phase transitions in the early universe at grand unification or partial unification scales. The general arguments are illustrated by consideration of SO(10) and SU(5) grand unified theories. (orig.)

  11. Fetal Outcomes among Grand Multiparous and Multiparous Women ...

    African Journals Online (AJOL)

    Objective: To compare fetal outcomes among grand multiparous (para 5-9) and multiparous (para 2-4) delivering in Mulago hospital, Uganda. Design: Prospective cohort study. Setting: Mulago hospital, Uganda. Subjects: One hundred and fifty six grand multiparous and multiparous women were recruited on admission in ...

  12. First report of Phytophthora ramorum infecting grand fir in California

    Science.gov (United States)

    K.L. Riley; G.A. Chastagner

    2011-01-01

    Phytophthora ramorum was detected on grand fir in 2003 and 2005 in a Christmas tree plantation near Los Gatos, CA, in association with infected California bay laurel. Isolates derived from stem lesions were used to inoculate grand fir seedlings in two tests. Isolations from lesions on inoculated plants were positive for P. ramorum...

  13. Plants, arthropods, and birds of the Rio Grande [chapter 7

    Science.gov (United States)

    Deborah M. Finch; Gale L. Wolters; Wang Yong; Mary Jean Mund

    1995-01-01

    Human populations have increased dramatically along the Rio Grande since European settlement. Human use of water for irrigation and consumption, and human use of land for agriculture, urban centers, livestock grazing, and recreation have changed Rio Grande ecosystems by altering flood cycles, channel geomorphology, upslope processes, and water quality and quantity....

  14. Research of the Rio Grande Ecosystem Management Program

    Science.gov (United States)

    Deborah M. Finch

    2000-01-01

    This paper describes the mission, objectives, and preliminary results of the Middle Rio Grande Ecosystem Management Research Program managed at the Rocky Mountain Research Station's Albuquerque laboratory. This program was initiated in 1994 to address growing pressures to effectively manage the limited resources of the middle Rio Grande Basin. The program is...

  15. Elastoplasticidad anisotropa de metales en grandes deformaciones

    Science.gov (United States)

    Caminero Torija, Miguel Angel

    El objetivo de este trabajo es el desarrollo de modelos y algoritmos numericos que simulen el comportamiento del material bajo estas condiciones en el contexto de programas de elementos finitos, dando como resultado predicciones mas precisas de los procesos de conformado y deformacion plastica en general. Para lograr este objetivo se han desarrollado diversas tareas destinadas a mejorar las predicciones en tres aspectos fundamentales. El primer aspecto consiste en la mejora de la descripcion del endurecimiento cinematico anisotropo en pequenas deformaciones, lo cual se ha realizado a traves de modelos y algoritmos implicitos de superficies multiples. Ha sido estudiada la consistencia de este tipo de modelos tanto si estan basados en una regla implicita similar a la de Mroz o en la regla de Prager. Ademas se han simulado los ensayos de Lamba y Sidebottom, obteniendo, en contra de la creencia general, muy buenas predicciones con la regla de Prager. Dichos modelos podrian ser extendidos de forma relativamente facil para considerar grandes deformaciones a traves de procedimientos en deformaciones logaritmicas, similares a los desarrollados en esta tesis y detallados a continuacion. El segundo aspecto consiste en la descripcion de la anisotropia elastoplastica inicial. Esto se ha conseguido mediante el desarrollo de modelos y algoritmos para plasticidad anisotropa en grandes deformaciones, bien ignorando la posible anisotropia elastica, bien considerandola simultaneamente con la anisotropia plastica. Para ello ha sido necesario desarrollar primero un nuevo algoritmo de elastoplasticidad anisotropa en pequenas deformaciones consistentemente linealizado y sin despreciar ningun termino, de tal forma que se conserve la convergencia cuadratica de los metodos de Newton. Este algoritmo en pequenas deformaciones ha servido para realizar la correccion plastica de dos algoritmos en grandes deformaciones. El primero de estos algoritmos es una variacion del clasico algoritmo de

  16. Grande-Baie tugboat sinking and salvage operations

    International Nuclear Information System (INIS)

    Dussault, M.; Gauthier, F.

    2009-01-01

    This paper described the operations that took place during an oil spill that occurred in December 2007 when the Grande-Baie tugboat sank at the wharf in Port Alfred, in the Ha-Ha Bay on the Saguenay River, Quebec. Approximately 100 tonnes of diesel fuel was onboard the tug. Although the exact amount of diesel spilled during this event is not known, it is assumed that half of the ship's load in diesel was spilled into the ice-infested waters. Poor weather, the presence of pack ice and tides of 2.5 meters were present at the time. Two Canadian Coast Guard officers, one emergency officer from Environment Quebec and one from Environment Canada were called for response purposes, particularly to avoid spreading of the diesel fuel and to ensure that the oily water was recovered from inside the vessel during salvage operations. One of the key objectives was to prevent diesel spills by capping vessel vents, which proved to be very challenging. Oily water was pumped from inside the boat directly in the bay of the Saguenay River to facilitate salvage of the ship. This was the first time that this method was used in Canada, and was successful because of proper risk assessment. Many conditions were followed for the purpose of environmental protection, such as confinement, good observations by divers, agreed upon criteria to stop pumping, and adequate monitoring the the Regional Environmental Emergency Team (REET). The salvage operation lasted 19 days. The challenges associated with the migration and recovery of oil in icy waters were discussed along with the environmental issues associated with the spill, particularly with the imminent opening of the ice fishing season. 2 refs., 2 tabs.,5 figs.

  17. Coordinating the Atlantis Grand Opening Event

    Science.gov (United States)

    Smith, Abigail Allaine

    2013-01-01

    While working as the marketing intern for Kennedy Space Center's (KSC) Center Planning and Development Directorate (CPD), I was given the opportunity not only to learn new skills and expand my work experience under the powerful influence of NASA, but I also was given the opportunity to prove that I am an individual capable of contributing to the KSC team. My main responsibility while working in CPD was to organize and run a booth that represented the entire directorate at the Grand Opening of the Shuttle Atlantis exhibit during the weekend of June 28-30. This event was important for CPD because as a Directorate that markets KSC's facilities, technical capabilities and technologies to potential partners, it is important to attend all events and use them to gain an understanding of our audience. Although we catered mostly to the general public during this event, it was still important to reach out to the larger space enthusiast community and let them know about KSC's future plans to become a multi-user spaceport and that teclmology is still being developed.

  18. The grand descent has begun for CMS

    CERN Multimedia

    2006-01-01

    Until recently, the CMS experimental cavern looked relatively empty; its detector was assembled entirely at ground level, to be lowered underground in 15 sections. On 2 November, the first hadronic forward calorimeter led the way with a grand descent. The first section of the CMS detector (centre of photo) arriving from the vertical shaft, viewed from the cavern floor. There is something unusual about the construction of the CMS detector. Instead of being built in the experimental cavern, like all the other detectors in the LHC experiments, it was constructed at ground level. This was to allow for easy access during the assembly of the detector and to minimise the size of the excavated cavern. The slightly nerve-wracking task of lowering it safely into the cavern in separate sections came after the complete detector was successfully tested with a magnetic field at ground level. In the early morning of 2 November, the first section of the CMS detector began its eagerly awaited descent into the underground ca...

  19. Local grand unification in the heterotic landscape

    International Nuclear Information System (INIS)

    Schmidt, Jonas

    2009-06-01

    We consider the possibility that the unification of the electroweak interactions and the strong force arises from string theory, at energies significantly lower than the string scale. As a tool, an effective grand unified field theory in six dimensions is derived from an anisotropic orbifold compactification of the heterotic string. It is explicitly shown that all anomalies cancel in the model, though anomalous Abelian gauge symmetries are present locally at the boundary singularities. In the supersymmetric vacuum additional interactions arise from higher-dimensional operators. We develop methods that relate the couplings of the effective theory to the location of the vacuum, and find that unbroken discrete symmetries play an important role for the phenomenology of orbifold models. An efficient algorithm for the calculation of the superpotential to arbitrary order is developed, based on symmetry arguments. We furthermore present a correspondence between bulk fields of the orbifold model in six dimensions, and the moduli fields that arise from compactifying four internal dimensions on a manifold with non-trivial gauge background. (orig.)

  20. Gauge hierarchy problem in grand unified theories

    International Nuclear Information System (INIS)

    Alhendi, H.A.A.

    1982-01-01

    In grand unification schemes, several mass scales are to be introduced, with some of them much larger than all the others, to cope with experimental observations, in which elementary particles of higher masses require higher energy to observe them than elementary particles of lower masses. There have been controversial arguments in the literature on such hierarchical scale structure, when radiative corrections are taken into account. It has been asserted that the gauge hierarchy depends on the choice of the subtraction point (in the classical field space), of the four-point function at zero external momentum. It also has been asserted that the gauge hierarchy problem whenever it is possible to be maintained in one sector of particles, it also is possible to be maintained in the other sectors. These two problems have been studied in a prototype model, namely an 0(3)-model with two triplets of real scalar Higgs fields. Our analysis shows that, within ordinary perturbation theory, none of these two problems is quite correct

  1. Integrated telemedicine workstation for intercontinental grand rounds

    Science.gov (United States)

    Willis, Charles E.; Leckie, Robert G.; Brink, Linda; Goeringer, Fred

    1995-04-01

    The Telemedicine Spacebridge to Moscow was a series of intercontinental sessions sponsored jointly by NASA and the Moscow Academy of Medicine. To improve the quality of medical images presented, the MDIS Project developed a workstation for acquisition, storage, and interactive display of radiology and pathology images. The workstation was based on a Macintosh IIfx platform with a laser digitizer for radiographs and video capture capability for microscope images. Images were transmitted via the Russian Lyoutch Satellite which had only a single video channel available and no high speed data channels. Two workstations were configured -- one for use at the Uniformed Services University of Health Sciences in Bethesda, MD. and the other for use at the Hospital of the Interior in Moscow, Russia. The two workstations were used may times during 16 sessions. As clinicians used the systems, we modified the original configuration to improve interactive use. This project demonstrated that numerous acquisition and output devices could be brought together in a single interactive workstation. The video images were satisfactory for remote consultation in a grand rounds format.

  2. Grand unification in the projective plane

    International Nuclear Information System (INIS)

    Hebecker, A.

    2004-01-01

    A 6-dimensional grand unified theory with the compact space having the topology of a real projective plane, i.e., a 2-sphere with opposite points identified, is considered. The space is locally flat except for two conical singularities where the curvature is concentrated. One supersymmetry is preserved in the effective 4d theory. The unified gauge symmetry, for example SU(5), is broken only by the non-trivial global topology. In contrast to the Hosotani mechanism, no adjoint Wilson-line modulus associated with this breaking appears. Since, locally, SU(5) remains a good symmetry everywhere, no UV-sensitive threshold corrections arise and SU(5)-violating local operators are forbidden. Doublet-triplet splitting can be addressed in the context of a 6d N=2 super Yang-Mills theory with gauge group SU(6). If this symmetry is first broken to SU(5) at a fixed point and then further reduced to the standard model group in the above non-local way, the two light Higgs doublets of the MSSM are predicted by the group-theoretical and geometrical structure of the model. (author)

  3. y las grandes ciudades: 1970-2004

    Directory of Open Access Journals (Sweden)

    Adrián de León Arias

    2008-01-01

    Full Text Available El cambio regional en las manufacturas mexicanas a partir de la década de 1980 se ha caracterizado por el rápido crecimiento del empleo y la producción en la frontera norte del país y la pérdida de participación de ellos en las grandes ciudades. En este artículo se analiza y evalúa este cambio regional en términos de la dinámica de la productividad laboral y factorial total para ambas configuraciones espaciales, presentando cálculos de productividad para éstas de 1970 a 2004, estimados a partir de la información censal. Los resultados sugieren que mientras el empleo ha crecido en magnitud mucho más rápido en la frontera norte, esta dinámica se ha generado con bajos niveles en crecimiento de la productividad, al menos hasta fechas recientes, por lo que el cambio regional estimulado por la apertura comercial hasta 2004 no parece haber facilitado un crecimiento económico más acelerado para México

  4. Local grand unification in the heterotic landscape

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Jonas

    2009-07-15

    We consider the possibility that the unification of the electroweak interactions and the strong force arises from string theory, at energies significantly lower than the string scale. As a tool, an effective grand unified field theory in six dimensions is derived from an anisotropic orbifold compactification of the heterotic string. It is explicitly shown that all anomalies cancel in the model, though anomalous Abelian gauge symmetries are present locally at the boundary singularities. In the supersymmetric vacuum additional interactions arise from higher-dimensional operators. We develop methods that relate the couplings of the effective theory to the location of the vacuum, and find that unbroken discrete symmetries play an important role for the phenomenology of orbifold models. An efficient algorithm for the calculation of the superpotential to arbitrary order is developed, based on symmetry arguments. We furthermore present a correspondence between bulk fields of the orbifold model in six dimensions, and the moduli fields that arise from compactifying four internal dimensions on a manifold with non-trivial gauge background. (orig.)

  5. Constraints on grand unified superstring theories

    International Nuclear Information System (INIS)

    Ellis, J.; Lopez, J.L.; Nanopoulos, D.V.; Houston Advanced Research Center

    1990-01-01

    We evaluate some constraints on the construction of grand unified superstring theories (GUSTs) using higher level Kac-Moody algebras on the world-sheet. In the most general formulation of the heterotic string in four dimensions, an analysis of the basic GUST model-building constraints, including a realistic hidden gauge group, reveals that there are no E 6 models and any SO(10) models can only exist at level-5. Also, any such SU(5) models can exist only for levels 4≤k≤19. These SO(10) and SU(5) models risk having many large, massless, phenomenologically troublesome representations. We also show that with a suitable hidden sector gauge group, it is possible to avoid free light fractionally charged particles, which are endemic to string derived models. We list all such groups and their representations for the flipped SU(5)xU(1) model. We conclude that a sufficiently binding hidden sector gauge group becomes a basic model-building constraint. (orig.)

  6. A unified grand tour of theoretical physics

    CERN Document Server

    Griffiths, J

    2002-01-01

    Anyone offering a grand tour is faced with several options. Should they concentrate on what may be considered to be essential features, or should they attempt to present a brief glimpse of almost everything? The present offering is a compromise between these two extremes. The area considered - theoretical physics - is now such a vast subject that some kind of compromise is essential. Indeed, the field is now so wide that few could even attempt to review it in a single-authored work. My task here is to assess how well this book has succeeded in its main aim of providing a unified (though introductory) tour of this subject. Constrained within a single volume, this is clearly not an updated Landau-Lifschitz. It cannot be expected to take any particular topic to the level of recent research. Nevertheless, it does seem to cover the broad range of essential topics which now constitute the subject. It starts (most appropriately in my opinion) with geometry. It then covers classical physics, general relativity and qu...

  7. Overcoming challenges

    Medline Plus

    Full Text Available ... breastfeeding Overcoming challenges Common questions about breastfeeding and pain Breastfeeding checklist: How to get a good latch Finding ... myths Overcoming challenges Common questions about breastfeeding and pain Breastfeeding checklist: How to get a good latch Finding ...

  8. Overcoming challenges

    Medline Plus

    Full Text Available ... section Back to section menu It's Only Natural Planning ahead Breastfeeding and baby basics Making breastfeeding work ... It's Only Natural Overcoming challenges It's Only Natural Planning ahead Addressing breastfeeding myths Overcoming challenges Common questions ...

  9. VT Built Up Lands in Grand Isle County - 1986

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) NRCS mapped historical and current-day built-up lands for Grand Isle County, VT using several vintages of aerial photography: 1941, 1962, 1974,...

  10. VT Built Up Lands in Grand Isle County - 1941

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) NRCS mapped historical and current-day built-up lands for Grand Isle County, VT using several vintages of aerial photography: 1941, 1962, 1974,...

  11. Constructing 5d orbifold grand unified theories from heterotic strings

    International Nuclear Information System (INIS)

    Kobayashi, Tatsuo; Raby, Stuart; Zhang Renjie

    2004-01-01

    A three-generation Pati-Salam model is constructed by compactifying the heterotic string on a particular T 6 /Z 6 Abelian symmetric orbifold with two discrete Wilson lines. The compactified space is taken to be the Lie algebra lattice G 2 -bar SU(3)-bar SO(4). When one dimension of the SO(4) lattice is large compared to the string scale, this model reproduces many features of a 5d SO(10) grand unified theory compactified on an S 1 /Z 2 orbifold. (Of course, with two large extra dimensions we can obtain a 6d SO(10) grand unified theory.) We identify the orbifold parities and other ingredients of the orbifold grand unified theories in the string model. Our construction provides a UV completion of orbifold grand unified theories, and gives new insights into both field theoretical and string theoretical constructions

  12. 27 CFR 9.119 - Middle Rio Grande Valley.

    Science.gov (United States)

    2010-04-01

    ... Middle Rio Grande Valley. (a) Name. The name of the viticultural area described in this section is... 1979. (24) Veguita, N. Mex. (1952), revised 1979. (25) Wind Mesa, N. Mex. (1952), revised 1967. (c...

  13. A GRAND PLAN FOR EARTH LOVE EDUCATION IN SOUTHERN ...

    African Journals Online (AJOL)

    cognition. From this doubtful synthesis, the researcher appears to have constructed a grand theory of how the world without ... problem here is that all of the students (English. Xhosa and ..... accompanying 'earthy music' will contrihute to.

  14. Casa Grande Ruins National Monument acoustical monitoring 2010

    Science.gov (United States)

    2014-11-01

    During September 2010, The Volpe Center collected baseline acoustical data at Casa Grande National Monument (CAGR), at one site for 28 days. The baseline data collected during this period will help park managers and planners estimate the effects of f...

  15. Flocculent and grand design spiral arm structure in cluster galaxies

    International Nuclear Information System (INIS)

    Elmegreen, D.M.

    1982-01-01

    A total of 829 spiral galaxies in 22 clusters having redshifts between z = 0.02 and 0.06 were classified according to the appearance of their spiral arm structures. The fraction of galaxies that have a grand design spiral structure was found to be higher among barred galaxies than among non-barred galaxies (at z = 0.02, 95 per cent of strongly barred galaxies have a grand design, compared with 67 per cent of non-barred or weakly barred galaxies). Cluster galaxies and distant non-cluster galaxies have the same fraction of grand design galaxies when resolution effects are considered. The grand design fraction among cluster galaxies is also similar to the fraction observed among nearby galaxies in binary systems and in groups. (author)

  16. Albuquerque/Middle Rio Grande Urban Waters Viewer

    Data.gov (United States)

    U.S. Environmental Protection Agency — These data have been compiled in support of the Middle Rio Grande/Albuquerque Urban Waters Partnership for the region including Albuquerque, New Mexico.The Middle...

  17. Nalisis Kinerja Keuangan pada PT. Grand Victoria Hotel di Samarinda

    OpenAIRE

    -, Atmajaya -

    2013-01-01

    Based on the results of analysis show that the performance of PT. Hotel Grand Victorian is measured using liquidity ratios and profitability ratios decreased from 2010-2012. Performance PT. Grand Victorian is measured using the liquidity ratio has decreased from year 2010-2012 consists of current ratio has decreased, and this is because the total current assets has increased and decreased. Meanwhile, the cash ratio from year 2010-2012 has increased, this is because the total cash and cash equ...

  18. Simulations of Precipitation Variability over the Upper Rio Grande Basin

    International Nuclear Information System (INIS)

    Costigan, Keeley R.; Bossert, James E.; Langley, David L.

    1997-10-01

    In this research, we study Albuquerque's water and how it may be affected by changes in the regional climate, as manifested by variations in Rio Grande water levels. To do this, we rely on the use of coupled atmospheric, runoff, and ground water models. Preliminary work on the project has focused on uncoupled simulations of the aquifer beneath Albuquerque and winter precipitation simulations of the upper Rio Grande Basin. The latter is discussed in this paper

  19. Restrictions on SU(5) as a grand unified theory

    International Nuclear Information System (INIS)

    Shellard, R.C.

    1984-01-01

    Some restrictions imposed upon Grand Unified Theories by dynamical symetry breakdown are examined. They are shown that, in particular, theories SU(5) as symmetry group, with 3 or more fermion families undergo dynamical symmetry breakdown, and some of the fermions will acquire mass at the Grand Unified scale. On the other hand, the SO(10) group, with 3 families is free from this problem. (Author) [pt

  20. Tres grandes plataformas marinas Mar del Norte

    Directory of Open Access Journals (Sweden)

    Soulas, R.

    1978-03-01

    Full Text Available This article analyzes the different building stages of three large sea platforms. After studying the structure's main characteristics, preparing scale models and calculating ail the elements, platform construction was carried out in three stages: — Dry-dock construction of the hull base. — Installation in the water and finishing the structure. — Immersion and bridge installation. Finally, the necessary operations to move the platform to its definite location were carried out. The structures are formed by a parallelepiped hull of reinforced concrete, divided into compartments by means of vertical orthogonals panels on top of which 2 or 4 piles are placed to support the bridge.

    En este artículo se analizan las diversas etapas en la realización de tres grandes plataformas marinas. Después de un estudio de las características principales de la estructura, ensayos en modelo reducido y cálculo de todos los elementos, se procede a la construcción de las plataformas en tres fases: — Construcción en seco de la base del casco. — Colocación en el agua y acabado de la estructura. — Inmersión y colocación del puente. Por último, se realizan las operaciones necesarias para llevar la plataforma a su ubicación definitiva. Las estructuras están formadas por un casco paralelepipédico de hormigón armado, dividido en compartimientos mediante tabiques verticales ortogonales y sobre el que se han colocado 2 ó 4 pilas que soportan el puente.

  1. A roadmap for security challenges in the Internet of Things

    Directory of Open Access Journals (Sweden)

    Arbia Riahi Sfar

    2018-04-01

    Full Text Available Unquestionably, communicating entities (object, or things in the Internet of Things (IoT context are playing an active role in human activities, systems and processes. The high connectivity of intelligent objects and their severe constraints lead to many security challenges, which are not included in the classical formulation of security problems and solutions. The Security Shield for IoT has been identified by DARPA (Defense Advanced Research Projects Agency as one of the four projects with a potential impact broader than the Internet itself. To help interested researchers contribute to this research area, an overview of the IoT security roadmap overview is presented in this paper based on a novel cognitive and systemic approach. The role of each component of the approach is explained, we also study its interactions with the other main components, and their impact on the overall. A case study is presented to highlight the components and interactions of the systemic and cognitive approach. Then, security questions about privacy, trust, identification, and access control are discussed. According to the novel taxonomy of the IoT framework, different research challenges are highlighted, important solutions and research activities are revealed, and interesting research directions are proposed. In addition, current standardization activities are surveyed and discussed to the ensure the security of IoT components and applications. Keywords: Internet of Things, Systemic and cognitive approach, Security, Privacy, Trust, Identification, Access control

  2. Enterotoxemia em caprinos no Rio Grande do Sul Caprine enterotoxaemia in Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Edson M. Colodel

    2003-12-01

    Full Text Available São descritos surtos de enterotoxemia em caprinos em cinco propriedades no Estado do Rio Grande do Sul. Os animais afetados eram, normalmente, encontrados mortos ou apresentavam evolução aguda de 2 a 3 horas com acentuada depressão, cólicas abdominais e diarréia profusa com fibrina. Em duas propriedades relataram-se casos com a evolução de até 12 horas. Em treze animais necropsiados observaram-se aumento de líquidos nas cavidades abdominal, torácica e pericárdica, congestão e hiperemia da serosa e mucosa do intestino, conteúdo do cólon líquido com fibrina além de hemorragias de serosa e fibrina. Em um animal constatou-se microangiopatia cerebral caracterizada por acúmulo de material homogêneo e eosinofílico no espaço perivascular. No conteúdo intestinal, colônias com bastonetes morfológica e bioquimicamente sugestivos de Clostridium perfringens foram caracterizadas no estudo bacteriológico. A soroneutralização em camundongos com conteúdo intestinal dos animais afetados, revelou a presença da toxina épsilon. Estes achados evidenciam a enterotoxemia como doença de importância para criação de caprinos no Rio Grande do Sul.Five outbreaks of caprine enterotoxaemia in Rio Grande do Sul, Brazil, were studied. The animals were found dead or had a clinical course that usually lasted 2-3 hours. From two farms a clinical manifestation period of 12 hours was reported. Clinical signs were characterized by depression, marked abdominal discomfort, profuse watery diarrhea with fibrin clots, and death. Thirteen necropsies were performed and hydropericardium, hydrothorax and hydroperitoneum were commonly found. The mucosa and serosa of the colon were congested, and its contents was watery with multiple fibrin clots. Serosal hemorrhages and fibrin clots in the gallbladder were also seen. Fibrinous colitis and thyphilitis were the most frequent histological changes. Cerebral microangiopathy was observed in one case, which was

  3. 3D View of Grand Canyon, Arizona

    Science.gov (United States)

    2000-01-01

    The Grand Canyon is one of North America's most spectacular geologic features. Carved primarily by the Colorado River over the past six million years, the canyon sports vertical drops of 5,000 feet and spans a 445-kilometer-long stretch of Arizona desert. The strata along the steep walls of the canyon form a record of geologic time from the Paleozoic Era (250 million years ago) to the Precambrian (1.7 billion years ago).The above view was acquired by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument aboard the Terra spacecraft. Visible and near infrared data were combined to form an image that simulates the natural colors of water and vegetation. Rock colors, however, are not accurate. The image data were combined with elevation data to produce this perspective view, with no vertical exaggeration, looking from above the South Rim up Bright Angel Canyon towards the North Rim. The light lines on the plateau at lower right are the roads around the Canyon View Information Plaza. The Bright Angel Trail, which reaches the Colorado in 11.3 kilometers, can be seen dropping into the canyon over Plateau Point at bottom center. The blue and black areas on the North Rim indicate a forest fire that was smoldering as the data were acquired on May 12, 2000.Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of International Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, Calif., is the U.S. Science team leader; Moshe Pniel of JPL is the project manager. ASTER is the only high resolution imaging sensor on Terra. The primary goal of the ASTER mission is to obtain high-resolution image data in 14 channels over the entire land surface, as

  4. Perfluoroalkyl substances in waters along the Grand Canal, China.

    Science.gov (United States)

    Piao, H T; Jiao, X C; Gai, N; Chen, S; Lu, G H; Yin, X C; Yamazaki, E; Yamashita, N; Tan, K Y; Yang, Y L; Pan, J

    2017-07-01

    The Grand Canal, also known as the Beijing-Hangzhou Grand Canal, is a UNESCO World Heritage Site and the longest canal in the world. It is an important trunk line of the South-to-North Water Diversion Project in China. The contamination status and spatial distributions of perfluoroalky substances (PFASs) in waters of the Grand Canal were investigated. The total concentrations of PFASs (∑PFASs) range from 7.8 ng/L to 218.0 ng/L, with high ∑PFASs occurring in the southern part of the Grand Canal which is located in a highly urbanized and economically developed region. The dominance of PFOA showed a decreasing trend toward north while shorter chain homologue proportions increased in the northern part of the Canal which mainly traverses underdeveloped and rural areas in Eastern China. Positive correlations were observed between ∑PFASs and the population density as well as GDP per capita. Intersection with large rivers may affect the contamination levels and composition of PFASs in the water of the Grand Canal near the intersection sites. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Flocculent and grand design spiral galaxies in groups: time scales for the persistence of grand design spiral structures

    International Nuclear Information System (INIS)

    Elmegreen, B.G.; Elmegreen, D.M.

    1983-01-01

    Spiral arm classifications were made for 261 low-inclination galaxies in groups listed by Huchra and Geller. The fractional occurrence of grand design spiral structure in nonbarred galaxies was found to increase from approx.0.1 to approx.0.6 and then level off as the group crossing rate or galaxy collision rate in a group increases. A simple model is discussed where the random encounters between galaxies of any type and flocculent galaxies induce transient grand design spirals in the flocculent galaxies. If this grand-design stimulation occurs for binary collisions with impact parameters less than αR 25 , were R 25 is the galactic radius at 25 mag arcsec - 2 , and if the induced grand design spirals persist for an average time equal to #betta# galactic rotations, then the quantity α 2 #betta# equals approximately 3 x 10 4 . If binary collisions are responsible for grand design spirals, then this result implies either that the induced spirals last for many galactic rotations (#betta#>15), or that they can be stimulated by very remote encounters (α>45.) Alternatively, grand design spirals may be stimulated by multiple galaxy encounters, which would be the case for such large α, or by interactions with the potential well of the associated group, rather than by simple binary encounters. Weak correlations between the grand design fraction and the galaxy size, or between this fraction and the total number of galaxies in a group, were also found. Spiral structures of barred galaxies show no correlations with group environment

  6. SO(10) - Grand unification and fermion masses

    International Nuclear Information System (INIS)

    Oezer, A.D.

    2005-01-01

    In this work, we study SO(10) grand unification in its full extent by using different explicit matrix representations which exhibit the structure of SO(10) in a very transparent way. Our approach consists mainly of two stages: We derive the explicit expressions of the mass-eigenvalues and mass-eigenstates of the physical gauge bosons from a mass squared-matrix that contains all the information about the mixing parameters among the gauge fields and the phases which are sources for CP violation. In the light of this analysis, we derive the explicit expressions for the interaction Lagrangians of the charged currents, the neutral currents and the charged and colored currents in SO(10). We present explicit expressions of the vector and axial-vector couplings of the two neutral currents in SO(10). We show how the baryon, lepton and baryon minus lepton number violating processes and their explicit CP violating phases are accommodated in the SO(10) theory. The Higgs potential that we use to implement in the Higgs mechanism is constructed in a most general fashion through a careful study of the Higgs fields of SO(10), where we give special emphasis on illustrating the explicit matrix representation of these Higgs fields. The potential part of the Higgs Lagrangian will give us the properties of the minimum of the vacuum, and the kinetic part will give us the mass-squared matrix of the gauge bosons via spontaneous symmetry breakdown. The same Higgs multiplets will be coupled to fermions through a democratic Yukawa matrix. Thereby, we derive explicit expressions for the fermion masses of the third family including Majorana and Dirac masses for neutrinos. We introduce a flavor-eigenbasis for neutrinos and find the mass-eigenstates and mass-eigenvalues of the neutrinos. Explicit expressions for CP violation in the neutrino sector are obtained. In the second stage of our work, we evaluate all the above mentioned quantities. In addition, we present the values of the physical

  7. Uncovering the Transnational Networks, Organisational Techniques and State-Corporate Ties Behind Grand Corruption: Building an Investigative Methodology

    Directory of Open Access Journals (Sweden)

    Kristian Lasslett

    2017-11-01

    Full Text Available While grand corruption is a major global governance challenge, researchers notably lack a systematic methodology for conducting qualitative research into its complex forms. To address this lacuna, the following article sets out and applies the corruption investigative framework (CIF, a methodology designed to generate a systematic, transferable approach for grand corruption research. Its utility will be demonstrated employing a case study that centres on an Australian-led megaproject being built in Papua New Guinea’s capital city, Port Moresby. Unlike conventional analyses of corruption in Papua New Guinea, which emphasise its local characteristics and patrimonial qualities, application of CIF uncovered new empirical layers that centre on transnational state-corporate power, the ambiguity of civil society, and the structural inequalities that marginalise resistance movements. The important theoretical consequences of the findings and underpinning methodology are explored.

  8. Biomechanical analysis technique choreographic movements (for example, "grand battman jete"

    Directory of Open Access Journals (Sweden)

    Batieieva N.P.

    2015-04-01

    Full Text Available Purpose : biomechanical analysis of the execution of choreographic movement "grand battman jete". Material : the study involved students (n = 7 of the department of classical choreography faculty of choreography. Results : biomechanical analysis of choreographic movement "grand battman jete" (classic exercise, obtained kinematic characteristics (path, velocity, acceleration, force of the center of mass (CM bio parts of the body artist (foot, shin, thigh. Built bio kinematic model (phase. The energy characteristics - mechanical work and kinetic energy units legs when performing choreographic movement "grand battman jete". Conclusions : It was found that the ability of an athlete and coach-choreographer analyze the biomechanics of movement has a positive effect on the improvement of choreographic training of qualified athletes in gymnastics (sport, art, figure skating and dance sports.

  9. Liberating methodological thinking in human sciences from grand theories

    DEFF Research Database (Denmark)

    Kharlamov, Nikita; Baldursson, Einar Baldvin

    2016-01-01

    focus on the necessity of a “grand unified theory” at the expense of any and all alternative perspectives. Properties of grand theories are discussed on the examples of Giddens and Bourdieu. It is argued that grand theories hamper a more productive focus on concrete phenomena. Robert Merton’s focus......Many humanistic and social disciplines are naturally inclined to seek for human-, person-, self- centered focus, and develop a holistic theory of such. Such disciplines continually engage with philosophical, metaphysical and meta-theoretical perspectives. This engagement often leads to a singular...... on “middle range” theories is revisited and its continuing relevance is highlighted. The level of abstraction characteristic of such theories, as well as the way they engage with the empirical social reality, are discussed. The article concludes by considering the paradoxical reductionism that can...

  10. High-Performance Corrosion-Resistant Materials: Iron-Based Amorphous-Metal Thermal-Spray Coatings: SAM HPCRM Program ? FY04 Annual Report ? Rev. 0 - DARPA DSO and DOE OCRWM Co-Sponsored Advanced Materials Program

    International Nuclear Information System (INIS)

    Farmer, J; Haslam, J; Wong, F; Ji, S; Day, S; Branagan, D; Marshall, M; Meacham, B; Buffa, E; Blue, C; Rivard, J; Beardsley, M; Buffa, E; Blue, C; Rivard, J; Beardsley, M; Weaver, D; Aprigliano, L; Kohler, L; Bayles, R; Lemieux, E; Wolejsza, T; Martin, F; Yang, N; Lucadamo, G; Perepezko, J; Hildal, K; Kaufman, L; Heuer, A; Ernst, F; Michal, G; Kahn, H; Lavernia, E

    2007-01-01

    The multi-institutional High Performance Corrosion Resistant Materials (HPCRM) Team is cosponsored by the Defense Advanced Projects Agency (DARPA) Defense Science Office (DSO) and the Department of Energy (DOE) Office of Civilian Radioactive Waste Management (OCRWM), and has developed new corrosion-resistant, iron-based amorphous metals that can be applied as coatings with advanced thermal spray technology. Two compositions have corrosion resistance superior to wrought nickel-based Alloy C-22 (UNS No. N06022) in very aggressive environments, including concentrated calcium-chloride brines at elevated temperature. Corrosion costs the Department of Defense billions of dollars every year, with an immense quantity of material in various structures undergoing corrosion. For example, in addition to fluid and seawater piping, ballast tanks, and propulsions systems, approximately 345 million square feet of structure aboard naval ships and crafts require costly corrosion control measures. The use of advanced corrosion-resistant materials to prevent the continuous degradation of this massive surface area would be extremely beneficial. The Fe-based corrosion-resistant, amorphous-metal coatings under development may prove of importance for applications on ships. Such coatings could be used as an 'integral drip shield' on spent fuel containers, as well as protective coatings that could be applied over welds, thereby preventing exposure to environments that might cause stress corrosion cracking. In the future, such new high-performance iron-based materials could be substituted for more-expensive nickel-based alloys, thereby enabling a reduction in the $58-billion life cycle cost for the long-term storage of the Nation's spent nuclear fuel by tens of percent

  11. High-Performance Corrosion-Resistant Materials: Iron-Based Amorphous-Metal Thermal-Spray Coatings: SAM HPCRM Program ? FY04 Annual Report ? Rev. 0 - DARPA DSO & DOE OCRWM Co-Sponsored Advanced Materials Program

    Energy Technology Data Exchange (ETDEWEB)

    Farmer, J; Haslam, J; Wong, F; Ji, S; Day, S; Branagan, D; Marshall, M; Meacham, B; Buffa, E; Blue, C; Rivard, J; Beardsley, M; Buffa, E; Blue, C; Rivard, J; Beardsley, M; Weaver, D; Aprigliano, L; Kohler, L; Bayles, R; Lemieux, E; Wolejsza, T; Martin, F; Yang, N; Lucadamo, G; Perepezko, J; Hildal, K; Kaufman, L; Heuer, A; Ernst, F; Michal, G; Kahn, H; Lavernia, E

    2007-09-19

    The multi-institutional High Performance Corrosion Resistant Materials (HPCRM) Team is cosponsored by the Defense Advanced Projects Agency (DARPA) Defense Science Office (DSO) and the Department of Energy (DOE) Office of Civilian Radioactive Waste Management (OCRWM), and has developed new corrosion-resistant, iron-based amorphous metals that can be applied as coatings with advanced thermal spray technology. Two compositions have corrosion resistance superior to wrought nickel-based Alloy C-22 (UNS No. N06022) in very aggressive environments, including concentrated calcium-chloride brines at elevated temperature. Corrosion costs the Department of Defense billions of dollars every year, with an immense quantity of material in various structures undergoing corrosion. For example, in addition to fluid and seawater piping, ballast tanks, and propulsions systems, approximately 345 million square feet of structure aboard naval ships and crafts require costly corrosion control measures. The use of advanced corrosion-resistant materials to prevent the continuous degradation of this massive surface area would be extremely beneficial. The Fe-based corrosion-resistant, amorphous-metal coatings under development may prove of importance for applications on ships. Such coatings could be used as an 'integral drip shield' on spent fuel containers, as well as protective coatings that could be applied over welds, thereby preventing exposure to environments that might cause stress corrosion cracking. In the future, such new high-performance iron-based materials could be substituted for more-expensive nickel-based alloys, thereby enabling a reduction in the $58-billion life cycle cost for the long-term storage of the Nation's spent nuclear fuel by tens of percent.

  12. Environmental Audit of the Grand Junction Projects Office

    Energy Technology Data Exchange (ETDEWEB)

    1991-08-01

    The Grand Junction Projects Office (GJPO) is located in Mesa County, Colorado, immediately south and west of the Grand Junction city limits. The US Atomic Energy Commission (AEC) established the Colorado Raw Materials Office at the present-day Grand Junction Projects Office in 1947, to aid in the development of a viable domestic uranium industry. Activities at the site included sampling uranium concentrate; pilot-plant milling research, including testing and processing of uranium ores; and operation of a uranium mill pilot plant from 1954 to 1958. The last shipment of uranium concentrate was sent from GJPO in January, 1975. Since that time the site has been utilized to support various DOE programs, such as the former National Uranium Resource Evaluation (NURE) Program, the Uranium Mill Tailings Remedial Action Project (UMTRAP), the Surplus Facilities Management Program (SFMP), and the Technical Measurements Center (TMC). All known contamination at GJPO is believed to be the result of the past uranium milling, analyses, and storage activities. Hazards associated with the wastes impounded at GJPO include surface and ground-water contamination and potential radon and gamma-radiation exposure. This report documents the results of the Baseline Environmental Audit conducted at Grand Junction Projects Office (GJPO) located in Grand Junction, Colorado. The Grand Junction Baseline Environmental Audit was conducted from May 28 to June 12, 1991, by the Office of Environmental Audit (EH-24). This Audit evaluated environmental programs and activities at GJPO, as well as GJPO activities at the State-Owned Temporary Repository. 4 figs., 12 tabs.

  13. Regional economic impacts of Grand Canyon river runners.

    Science.gov (United States)

    Hjerpe, Evan E; Kim, Yeon-Su

    2007-10-01

    Economic impact analysis (EIA) of outdoor recreation can provide critical social information concerning the utilization of natural resources. Outdoor recreation and other non-consumptive uses of resources are viewed as environmentally friendly alternatives to extractive-type industries. While outdoor recreation can be an appropriate use of resources, it generates both beneficial and adverse socioeconomic impacts on rural communities. The authors used EIA to assess the regional economic impacts of rafting in Grand Canyon National Park. The Grand Canyon region of northern Arizona represents a rural US economy that is highly dependent upon tourism and recreational expenditures. The purpose of this research is twofold. The first is to ascertain the previously unknown regional economic impacts of Grand Canyon river runners. The second purpose is to examine attributes of these economic impacts in terms of regional multipliers, leakage, and types of employment created. Most of the literature on economic impacts of outdoor recreation has focused strictly on the positive economic impacts, failing to illuminate the coinciding adverse and constraining economic impacts. Examining the attributes of economic impacts can highlight deficiencies and constraints that limit the economic benefits of recreation and tourism. Regional expenditure information was obtained by surveying non-commercial boaters and commercial outfitters. The authors used IMPLAN input-output modeling to assess direct, indirect, and induced effects of Grand Canyon river runners. Multipliers were calculated for output, employment, and income. Over 22,000 people rafted on the Colorado River through Grand Canyon National Park in 2001, resulting in an estimated $21,100,000 of regional expenditures to the greater Grand Canyon economy. However, over 50% of all rafting-related expenditures were not captured by the regional economy and many of the jobs created by the rafting industry are lower-wage and seasonal. Policy

  14. Environmental Audit of the Grand Junction Projects Office

    International Nuclear Information System (INIS)

    1991-08-01

    The Grand Junction Projects Office (GJPO) is located in Mesa County, Colorado, immediately south and west of the Grand Junction city limits. The US Atomic Energy Commission (AEC) established the Colorado Raw Materials Office at the present-day Grand Junction Projects Office in 1947, to aid in the development of a viable domestic uranium industry. Activities at the site included sampling uranium concentrate; pilot-plant milling research, including testing and processing of uranium ores; and operation of a uranium mill pilot plant from 1954 to 1958. The last shipment of uranium concentrate was sent from GJPO in January, 1975. Since that time the site has been utilized to support various DOE programs, such as the former National Uranium Resource Evaluation (NURE) Program, the Uranium Mill Tailings Remedial Action Project (UMTRAP), the Surplus Facilities Management Program (SFMP), and the Technical Measurements Center (TMC). All known contamination at GJPO is believed to be the result of the past uranium milling, analyses, and storage activities. Hazards associated with the wastes impounded at GJPO include surface and ground-water contamination and potential radon and gamma-radiation exposure. This report documents the results of the Baseline Environmental Audit conducted at Grand Junction Projects Office (GJPO) located in Grand Junction, Colorado. The Grand Junction Baseline Environmental Audit was conducted from May 28 to June 12, 1991, by the Office of Environmental Audit (EH-24). This Audit evaluated environmental programs and activities at GJPO, as well as GJPO activities at the State-Owned Temporary Repository. 4 figs., 12 tabs

  15. Pequena monografia sobre o Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Ana Maria Pinho

    2014-05-01

    Full Text Available Pequena monografia desenvolvida por membros do Colégio Sevigne, que versa sobre diversos assuntos a respeito do Rio Grande do Sul, divididos em histórico, fronteiras, organização política administrativa, características geográficas, formação geomorfológica, economia, aspectos históricos e geográficos da capital do Estado, generalidades étnicas, e sobre o gaúcho em si. Grande quantidade de ilustrações e poemas enriquecem o artigo.

  16. Severe accident sequences simulated at the Grand Gulf Nuclear Station

    International Nuclear Information System (INIS)

    Carbajo, J.J.

    1999-01-01

    Different severe accident sequences employing the MELCOR code, version 1.8.4 QK, have been simulated at the Grand Gulf Nuclear Station (Grand Gulf). The postulated severe accidents simulated are two low-pressure, short-term, station blackouts; two unmitigated small-break (SB) loss-of-coolant accidents (LOCAs) (SBLOCAs); and one unmitigated large LOCA (LLOCA). The purpose of this study was to calculate best-estimate timings of events and source terms for a wide range of severe accidents and to compare the plant response to these accidents

  17. Grand Minima: Is The Sun Going To Sleep?

    Science.gov (United States)

    Mcintosh, S. W.; Leamon, R. J.

    2014-12-01

    We explore recent observational work which indicate that the energetics of the sun's outer atmosphere have been on a steady decline for the past decade and perhaps longer. Futher, we show that new investigations into evolution of the Sun's global magnetic activity appear to demonstrate a path through which the Sun can go into, and exit from, a grand activity minimum without great difficulty while retaining an activity cycle - only losing sunspots. Are we at the begining of a new grand(-ish) minimum? Naturally, only time will tell, but the observational evidence hint that one may not be far off to what impact on the Sun-Earth Connection.

  18. Falares: a oralidade como elemento construtor da grande-reportagem

    OpenAIRE

    Alex Criado

    2006-01-01

    Esta tese discute a incorporação da oralidade de falantes excluídos social e culturalmente na grande-reportagem. O foco desta pesquisa é refletir como a grande-reportagem no Brasil, em sua missão de desvendamento do real, tem lidado com a questão da oralidade. Discute os desafios para a incorporação dos registros orais de pessoas com baixa escolaridade, tendo em vista o preconceito que existe na sociedade em relação aos falantes que se utilizam de modalidades diferentes da língua padrão. Prop...

  19. Mitigation measures for the La Grande 1 hydroelectric development

    International Nuclear Information System (INIS)

    Faucher, O.; Gagnon, R.

    1992-01-01

    Measures to mitigate environmental impacts of the La Grande 1 hydroelectric development are described. An overview is presented of the La Grande 1 project, its surrounding environment, and the principle environmental repercussions of the reservoir, hydrological changes between the dam and river mouth, construction activities and permanent and temporary structures, and presence of workers. Mitigation measures including compensation, corrective measures (deforestation, selective cutting, fish populations, wildlife populations, land rehabilitation, access roads, fisheries, and erosion control), protective measures, enhancement measures, and contract and employment opportunities for the Cree population are described. 10 refs., 2 figs

  20. Guidebook to Rio Grande rift in New Mexico

    Science.gov (United States)

    Hawley, J.W.

    1978-01-01

    Discusses the details of geologic features along the rift zone. Included are short papers on topics relative to the overall region. These papers and the road logs are of special interest to any one pursuing further study of the rift. This book is a comprehensive guide to the middle and late Cenozoic geology of the Rio Grande region of Colorado and New Mexico. Though initially used on field trips for the International Symposium on Tectonics and Magmatism of the Rio Grande rift, the guidebook will be useful to anyone interested in the Cenozoic history of the 600-mi-long area extending from central Colorado to El Paso, Texas.

  1. Overcoming challenges

    Medline Plus

    Full Text Available ... Disease and Stroke HIV and AIDS Mental Health Pain Pregnancy Reproductive Health Sexual Health Sexually Transmitted Infections ... breastfeeding Overcoming challenges Common questions about breastfeeding and pain Breastfeeding checklist: How to get a good latch ...

  2. Overcoming challenges

    Medline Plus

    Full Text Available ... menu It's Only Natural Planning ahead Breastfeeding and baby basics Making breastfeeding work for you Addressing breastfeeding ... in the African-American community Incredible facts about babies, breastmilk, and breastfeeding Overcoming challenges Common questions about ...

  3. Overcoming challenges

    Medline Plus

    Full Text Available ... facts about babies, breastmilk, and breastfeeding Overcoming challenges Common questions about breastfeeding and pain Breastfeeding checklist: How to get a good latch Finding support It takes a village: Building ...

  4. Cognitive Challenges

    Science.gov (United States)

    ... Alliance Our Story Our Vision Our Team Our Leadership Our Results Our Corporate Policies FAQs Careers Contact Us Media Store Privacy Policy Sitemap Learn Engage Donate About TSC Cognitive Challenges Approximately 45% to 60% of individuals with TSC ...

  5. Overcoming challenges

    Medline Plus

    Full Text Available ... breastfeeding means to them. Subscribe To receive Breastfeeding email updates Enter email Submit Overcoming challenges Breastfeeding has a long list ... breastfeeding means to them. Subscribe To receive Breastfeeding email updates Enter email Submit All material contained on ...

  6. Overcoming challenges

    Medline Plus

    Full Text Available ... into your life Breastfeeding in daily life: At home and in public Laws that support breastfeeding 10 ... and jobs View all pages in this section Home It's Only Natural Overcoming challenges It's Only Natural ...

  7. Mercury and selenium accumulation in the Colorado River food web, Grand Canyon, USA

    Science.gov (United States)

    Walters, David M.; E.J. Rosi-Marshall,; Kennedy, Theodore A.; W.F. Cross,; C.V. Baxter,

    2015-01-01

    Mercury (Hg) and selenium (Se) biomagnify in aquatic food webs and are toxic to fish and wildlife. The authors measured Hg and Se in organic matter, invertebrates, and fishes in the Colorado River food web at sites spanning 387 river km downstream of Glen Canyon Dam (AZ, USA). Concentrations were relatively high among sites compared with other large rivers (mean wet wt for 6 fishes was 0.17–1.59 μg g–1 Hg and 1.35–2.65 μg g–1 Se), but consistent longitudinal patterns in Hg or Se concentrations relative to the dam were lacking. Mercury increased (slope = 0.147) with δ15N, a metric of trophic position, indicating biomagnification similar to that observed in other freshwater systems. Organisms regularly exceeded exposure risk thresholds for wildlife and humans (6–100% and 56–100% of samples for Hg and Se, respectfully, among risk thresholds). In the Colorado River, Grand Canyon, Hg and Se concentrations pose exposure risks for fish, wildlife, and humans, and the findings of the present study add to a growing body of evidence showing that remote ecosystems are vulnerable to long-range transport and subsequent bioaccumulation of contaminants. Management of exposure risks in Grand Canyon will remain a challenge, as sources and transport mechanisms of Hg and Se extend far beyond park boundaries. Environ Toxicol Chem2015;9999:1–10

  8. La Grande Guerra fra realtà ed illusione: La Grande Illusion e l’immaginario

    Directory of Open Access Journals (Sweden)

    Simone Di Blasi

    2015-12-01

    Full Text Available The aim of this brief essay is to focus on the relation between the meaning of reality and illusion in the movie La Grande Illusion (1937 by Jean Renoir and therefore to find how these ideas of the author may be productive in a thought about the imaginary. After a short look on the movies made at that time on the First World War, there is an overview of the French director poetics, which redefines the conception of the realism, contextualizing its work at the point of convergence of two imaginary “technological lines”, the cinema and the aviation. It follows the analysis of the movie and the illusions, as social largely shared imaginaries, described by the author. In the end it is showed the importance and the of illusion in Renoir’s poetics. Beyond the relationship realityfiction, he thought a dynamic reciprocity among illusion and reality: so that the reality is as “illusion” (a ruled horizon in which it is possible to enjoy a world of play and the illusion as an activity creating contents of “reality”.

  9. FY 1992 Blue Book: Grand Challenges: High Performance Computing and Communications

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — High performance computing and computer communications networks are becoming increasingly important to scientific advancement, economic competition, and national...

  10. The grand challenge of developing in situ observational oceanography in South Africa

    CSIR Research Space (South Africa)

    Roberts, M

    2010-12-01

    Full Text Available , underwater temperature recorders (UTRs), wave buoys, as well as locally developed in situ measurement sensor and platform prototypes (dial-out UTRs, coastal and deep ocean buoys) have been incorporated into a regional in-situ observational network. A modular...

  11. GeoInquiries: Addressing a Grand Challenge for Teaching with GIS in Schools

    Science.gov (United States)

    DiBiase, D.; Baker, T.

    2016-12-01

    According to the National Research Council (2006), geographic information systems (GIS) is a powerful tool for expanding students' abilities to think spatially, a critical skill for future STEM professionals. However, educators in mainstream subjects in U.S. education have struggled for decades to use GIS effectively in classrooms. GeoInquiries are no cost, standards-based (NGSS or AP), Creative Commons-licensed instructional activities that guide inquiry around map-based concepts found in key subjects like Earth and environmental science. Web maps developed for GeoInquiries expand upon printed maps in leading textbooks by taking advantage of 21st GIS capabilities. GeoInquiry collections consist of 15 activities, each chosen to offer a map-based activity every few weeks throughout the school year. GeoInquiries use a common inquiry instructional framework, learned by many educators during their teacher preparation coursework. GeoInquiries are instructionally flexible - acting as much like building blocks for crafting custom activities as finished instructional materials. Over a half million geoinquiries will be accessed in the next twelve months - serving an anticipated 15 million students. After a generation of outreach to the educators, GIS is finally finding its way the mainstream.

  12. The scientific grand challenges of the 21st century for the Crop Science Society of America

    Science.gov (United States)

    Crop science is a highly integrative science field employing expertise from multiple disciplines to broaden our understanding of agronomic, turf, and forage crops. A major goal of crop science is to ensure an adequate and sustainable production of food, feed, fuel, and fiber for our world’s growing ...

  13. 77 FR 51983 - Availability of Department of Energy EV Everywhere Grand Challenge Initial Framing Document and...

    Science.gov (United States)

    2012-08-28

    ... optimal roles for the private sector, government laboratories, and academia in accelerating PEV technology... information? How can information on private sector innovation be captured without compromising competitive... international competitiveness against international cooperation? D. Program Definition and Management. What...

  14. FY 1993 Blue Book: Grand Challenges 1993: High Performance Computing and Communications

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — High performance computing and computer communications networks are becoming increasingly important to scientific advancement, economic competition, and national...

  15. New Capabilities for Hostile Environments on Z Grand Challenge LDRD - Final Status

    Energy Technology Data Exchange (ETDEWEB)

    Cuneo, Michael E. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Griffin, P. J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Balch, D. K. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Bell, K. S. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Bierner, J. A. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Coverdale, C. A. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Flanagan, T. M. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Hansen, S. B. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Slaboszewicz, V. Harper- [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Jones, B. M. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Lamppa, D. C. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Martin, W. J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); McKenney, J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Moore, N. W. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Parma, E. J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Peebles, H. C. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Rovang, D. C. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Savage, M. E. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Tang, R. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Vesey, R. A. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2016-10-01

    The purpose of this project was to develop new physical simulation capabilities in order to support the science-based qualification of nonnuclear weapon components in hostile radiation environments. The project contributes directly to the goals of maintaining a safe, secure, and effective US nuclear stockpile, maintaining strategic deterrence at lower nuclear force levels, extending the life of the nuclear deterrent capability, and to be ready for technological surprise.

  16. On the added value of forensic science and grand innovation challenges for the forensic community

    NARCIS (Netherlands)

    van Asten, A.C.

    2014-01-01

    In this paper the insights and results are presented of a long term and ongoing improvement effort within the Netherlands Forensic Institute (NFI) to establish a valuable innovation programme. From the overall perspective of the role and use of forensic science in the criminal justice system, the

  17. Grand Challenges: Science, Engineering, and Societal Advances, Requiring Networking and Information Technology Research and Development

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — ...the U.S. Government makes critical decisions about appropriate investments in IT R and D to help society forward both socially and economically. To inform that...

  18. Grand challenges in understanding the interplay of climate and land changes

    Science.gov (United States)

    Half of the Earth’s land surface has been altered by human activities, creating various consequences on the climate and weather systems at local to global scales, which in turn affects a myriad of land surface processes and our adaptation behaviors. After reviewing the status and major knowledge gap...

  19. Nuclear physics: large instruments and challenges; La physique nucleaire: les grands instruments et les defis

    Energy Technology Data Exchange (ETDEWEB)

    Harar, S. [CEA Centre d`Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France). Direction des Sciences de la Matiere

    1997-12-31

    Researches on nuclear physics and atomic nucleus can be divided into three periods of time at the CEA: from 1950 to 1970, the characteristics of atomic nucleus structure are measured and accelerators are used; in the early 70`s, heavy ion physics, with the Ganil accelerator, allows for the study of large perturbations in nuclei, while the meson physics study the nucleon interactions using the Saclay 700 MeV electron linear accelerator. In the early 90`s, the radioactive beams provided by the SPIRAL/Ganil device allows for the study of the nucleon internal structure, the quarks, and their effects while their deconfinement is studied by the means of the relativistic heavy ions provided by the LHC accelerator

  20. A Federal Vision for Future Computing: A Nanotechnology-Inspired Grand Challenge

    Science.gov (United States)

    2016-07-29

    fault-tolerant system that consumes less power than an incandescent light bulb. Recent progress in developing novel, low-power methods of sensing and...computation—including neuromorphic, magneto-electronic, and analog systems—combined with dramatic advances in neuroscience and cognitive sciences...enable ready-to-fabricate designs and specifications. 4. Brain-Inspired Approaches Neuroscience research suggests that the brain is a complex, high

  1. Grand Challenge Problem 3: Empowering Science Teachers Using Technology-Enhanced Scaffolding to Improve Inquiry Learning

    NARCIS (Netherlands)

    Pedaste, Margus; Lazonder, Adrianus W.; Raes, Annelies; Wajeman, Claire; Moore, Emily; Girault, Isabelle; Eberle, Julia; Lund, Kristine; Tchounikine, Pierre; Fischer, Frank

    2016-01-01

    Inquiry learning in technology-enhanced learning (TEL) environments has potential to support science learning. The “symbiosis” between teachers and TEL environments is needed and, therefore, virtual assistants should be “taught” based on pedagogical theories. These assistants should be dynamically

  2. Grand challenges in evolutionary and population genetics: The importance of integrating epigenetics, genomics, modeling, and experimentation

    Science.gov (United States)

    Samuel A. Cushman

    2014-01-01

    This is a time of explosive growth in the fields of evolutionary and population genetics, with whole genome sequencing and bioinformatics driving a transformative paradigm shift (Morozova and Marra, 2008). At the same time, advances in epigenetics are thoroughly transforming our understanding of evolutionary processes and their implications for populations, species and...

  3. Preventing Schizophrenia and Severe Mental Illness: A Grand Challenge for Social Work

    Science.gov (United States)

    DeVylder, Jordan E.

    2016-01-01

    Schizophrenia is a leading cause of disability and health expenditure worldwide and is associated with homelessness, substance use, familial and social isolation, unemployment, involvement with the criminal justice system, stigma, and excess mortality. Prevention may be feasible through intervention with help-seeking "clinical high-risk"…

  4. A DHS Skunkworks Project: Defining and Addressing Homeland Security Grand Challenges

    Science.gov (United States)

    2016-12-01

    million and one scotch and wine IOUs to Uncle Jay and Aunt Barb for their warm and endless hospitality. Finally, I would like to express my gratitude to... benefits of participation (e.g., reputation, visibility, opportunity to participate in technology development and accomplish other personal and...designs its future roadmap to achieve a massive transformational purpose (MTP) of bringing about radical breakthroughs for the benefit of humanity.37 An

  5. Carbonaceous aerosol particles from common vegetation in the Grand Canyon

    International Nuclear Information System (INIS)

    Hallock, K.A.; Mazurek, M.A.; Cass, G.R.

    1992-05-01

    The problem of visibility reduction in the Grand Canyon due to fine organic aerosol particles in the atmosphere has become an area of increased environmental concern. Aerosol particles can be derived from many emission sources. In this report, we focus on identifying organic aerosols derived from common vegetation in the Grand Canyon. These aerosols are expected to be significant contributors to the total atmospheric organic aerosol content. Aerosol samples from living vegetation were collected by resuspension of surface wax and resin components liberated from the leaves of vegetation common to areas of the Grand Canyon. The samples were analyzed using high-resolution gas chromatography/mass spectrometry (GC/MS). Probable identification of compounds was made by comparison of sample spectra with National Institute of Standards and Technology (NIST) mass spectral references and positive identification of compounds was made when possible by comparison with authentic standards as well as NIST references. Using these references, we have been able to positively identify the presence of n-alkane and n-alkanoic acid homolog series in the surface waxes of the vegetation sampled. Several monoterpenes, sesquiterpenes, and diterpenes were identified also as possible biogenic aerosols which may contribute to the total organic aerosol abundance leading to visibility reduction in the Grand Canyon

  6. Society and Health in the Lower Rio Grande Valley.

    Science.gov (United States)

    Madsen, William

    Shedding light on problems of mental health and illness that have baffled public health workers attempting to improve the health and welfare of Mexican Americans living in the lower Rio Grande Valley, this document reports the folk customs, social organization, medical practices, and beliefs of the Mexican American of this area. Chapters describe…

  7. Grand Manner Aesthetics in Landscape: From Canvas to Celluloid

    Science.gov (United States)

    Auger, Emily E.

    2009-01-01

    The methods by which environmental issues are aestheticized in late-twentieth-century film is directly and historically related to those established for grand manner painters by Nicholas Poussin (1594-1665) and taught at the French academy from the seventeenth through the nineteenth centuries. That these fundamentals were part of the training of…

  8. Os grandes consumidores de consultas medicas: um estudo de familia

    Directory of Open Access Journals (Sweden)

    M. Pereira Graça

    2002-01-01

    Full Text Available Este artículo describe un estudio sobre algunas características familiares de sujetos grandes consumidores de servicios de salud. Por un lado, se compara un grupo de grandes consumidores de servicios de salud, a nivel de número de consultas, con un grupo control en términos de funcionamiento familiar y actitudes hacia los médicos y la Medicina; por otro lado, se estudia la relación entre la dinámica familiar y las actitudes hacia la Medicina y los médicos en el grupo de los grandes consumidores. Los resultados muestran que los dos grupos de usuarios son significativamente diferentes; además, en el grupo de grandes consumidores el funcionamiento familiar problemático parece ser un factor intermediario en el desarrollo de actitudes menos negativas hacia los médicos y la Medicina. Se discuten las implicaciones que los resultados tienen a nivel de intervención terapéutica.

  9. Eesti nukufilm sai järjekordse grand prix

    Index Scriptorium Estoniae

    2005-01-01

    XII Rahvusvaheline animafilmifestival "KROK-2005", mis toimus laeval, mis sõitis Kiievist Odessasse. Rao Heidmets ja Hardi Volmer said festivali karnevalil oma jänese kostüümi eest grand prix. Eesti filmidest olid programmis "Karl ja Marilyn", "Frank ja Wendy", "Barbarid", "Laud" ja "Conkistadoor"

  10. Piccolo tõi Soomest taas grand prix'

    Index Scriptorium Estoniae

    2009-01-01

    Tänavuse Lappeenrantas toimunud rahvusvahelise suupillifestivali võistumängimisel osalesid suupilliklubi Piccolo orkester, kvartett ja noored solistid. Grand prix' ehk suure võidukarika pälvis Piccolo suupillikvartett koosseisus Ilmar Tõnisson, Andrus Haugas, Andres Kokk ja Elmar Trink. Noorte kategooria võitjaks tunnistati Martin Merevits, kolmandad kohad saavutasid Janek Sildvee bluusi- ja Eduard Einmann diatoonilise suupilli kategoorias

  11. Cosmological origin of the grand-unification mass scale

    International Nuclear Information System (INIS)

    Brout, R.; Englert, F.; Spindel, P.

    1979-01-01

    The origin of the universe as a quantum phenomenon leads to a self-consistently generated space-time structure in which the mass of the created particles is O (kappa/sup -1/2/). We interpret the origin of the universe as a phase transition in which the grand unified symmetry is spontaneously broken

  12. Nuove prospettive storiografiche sulla Grande guerra: violenze, traumi, esperienze

    Directory of Open Access Journals (Sweden)

    Marco Bizzocchi

    2014-03-01

    Full Text Available Il testo propone, attraverso l’analisi delle recensioni pubblicate sulla rivista internazionale “First World War Studies”, una rassegna su alcuni recenti studi storici sulla Prima guerra mondiale. Dopo la svolta degli anni Settanta-Ottanta, la storiografia sta continuando ad approfondire in particolare il tema dei risvolti sociali e culturali della Grande guerra.

  13. France's grandes écoles accused of elitism

    Science.gov (United States)

    Hellemans, Alexander

    2010-02-01

    Physicists in France have backed government plans to open up the country's elite grandes écoles to more students from poorer backgrounds. The government wants to allow up to 30% of students to be given free scholarships in an attempt to broaden the social mix of the student body. The physicists say this would not lead to a lowering of standards.

  14. Construction of calibration pads facility, Walker Field, Grand Junction, Colorado

    International Nuclear Information System (INIS)

    Ward, D.L.

    1978-08-01

    A gamma-ray spectrometer facility was completed at Walker Field Airport, Grand Junction, Colorado, in November 1976. This report describes spectrometers and their calibration, the construction of the spectrometer facility, the radioelement concentrations, procedures for using the facilites, and environmental considerations

  15. Cyber Resilience in de Bestuurskamer : The Grand Conference in Amsterdam

    NARCIS (Netherlands)

    Klaver, M.H.A.

    2013-01-01

    Op 16 oktober 2012 vond in Amsterdam The Grand Conference plaats. Deze conferentie werd georganiseerd door het Centre for the Protection of National lnfrastructure (CPNI.NL) in nauwe samenwerking met de Europese Commissie, de Europese Networkand Information Security Agency (ENISA), het Amerikaanse

  16. Winning in straight sets helps in Grand Slam tennis

    NARCIS (Netherlands)

    Goossens, Dries R.; Kempeneers, Jurgen; Koning, Ruud H.; Spieksma, Frits C. R.

    2015-01-01

    In this contribution, we study whether fatigue resulting from the previous match affects a player's chances of winning his (or her) next match in Grand Slum tennis. We measure relative fatigue levels of two opponents by looking at the difference in number of sets played in their previous match. We

  17. Masses of particles in the SO(18) grand unified model

    International Nuclear Information System (INIS)

    Asatryan, G.M.

    1984-01-01

    The grand unified model based on the orthogonal group SO(18) is treated. The model involves four familiar and four mirror families of fermions. Arising of masses of familiar and mirror particles is studied. The mass of the right-handed Wsub(R) boson interacting via right-handed current way is estimated

  18. A grand-canonical ensemble of randomly triangulated surfaces

    International Nuclear Information System (INIS)

    Jurkiewicz, J.; Krzywicki, A.; Petersson, B.

    1986-01-01

    An algorithm is presented generating the grand-canonical ensemble of discrete, randomly triangulated Polyakov surfaces. The algorithm is used to calculate the susceptibility exponent, which controls the existence of the continuum limit of the considered model, for the dimensionality of the embedding space ranging from 0 to 20. (orig.)

  19. Flood disaster preparedness: a retrospect from Grand Forks, North Dakota.

    Science.gov (United States)

    Siders, C; Jacobson, R

    1998-01-01

    Natural disasters often come without warning. The clinical, financial, and business risks can be enormous. Grand Forks' (ND) healthcare systems experienced a flooding disaster of unprecedented proportions in April of 1997. Planned and practiced disaster and evacuation procedures can significantly reduce a healthcare facilities' risk to life, health, and safety. This article retrospectively analyzes disaster preparation and the complete evacuation of the facilities' patients.

  20. Dynkin weights and global supersymmetry in grand unification

    International Nuclear Information System (INIS)

    Frampton, P.H.; Kephart, T.W.

    1982-01-01

    The requirement that supersymmetry be unbroken in a supersymmetrized gauge theory is shown to imply vanishing Dynkin weight of the components of the Higgs field representation receiving vacuum expectation values. As a corollary a compact expression is obtained for the Dynkin weights of general SU(N) representations. Examples are given for supersymmetrized grand unified theories

  1. The canonical and grand canonical models for nuclear ...

    Indian Academy of Sciences (India)

    Many observables seen in intermediate energy heavy-ion collisions can be explained on the basis of statistical equilibrium. Calculations based on statistical equilibrium can be implemented in microcanonical ensemble, canonical ensemble or grand canonical ensemble. This paper deals with calculations with canonical ...

  2. Interplay between grand unification and supersymmetry in SU(5 ...

    Indian Academy of Sciences (India)

    energy MSSM. break the rank, Aulakh and his collaborators [10–12] have showed that R-parity is exact all the way down to low energies. In this case, grand unification tells us something about supersymmetry and even dark matter. In this article ...

  3. Grande Ronde Basin Fish Habitat Enhancement Project : 1998 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, Vance R.; Powell, Russ M.

    1999-05-01

    The primary goal of ''The Grande Ronde Basin Fish Habitat Improvement Project'' is to access, create, improve, protect, and restore reparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin.

  4. Vegetation Versus Man-Made Object Detection from Imagery for Unmanned Vehicles in Off-Road Environments

    Science.gov (United States)

    2013-05-01

    saliency, natural scene statistics 1. INTRODUCTION Research into the area of autonomous navigation for unmanned ground vehicles (UGV) has accelerated in...recent years. This is partly due to the success of programs such as the DARPA Grand Challenge1 and the dream of driverless cars ,2 but is also due to the...NOTES 14. ABSTRACT There have been several major advances in autonomous navigation for unmanned ground vehicles in controlled urban environments in

  5. Capital Humano e Desenvolvimento Econômico no Rio Grande do Sul: Uma Abordagem Multivariada

    Directory of Open Access Journals (Sweden)

    Nilson Luiz Costa

    2017-01-01

    Full Text Available This article proposes an analysis from the theories linking human capital to economic development process. The method used consists of multivariate statistical techniques, particularly the Exploratory Factor Analysis and Conglomerates Analysis. Statistics were selected from 496 municipalities in the state of Rio Grande do Sul/Brazil according to their capacity to represents the dynamics of income concentration, quality of education and health, poverty, education and formal work. Among the results, there is a positive and direct association between levels of formal education and economic development, which validates the theoretical contributions of Theodore William Schultz and other authors that stem from their lineage. The results point to the importance of breaking the current paradigms and think education policy beyond the rhetoric of official speeches and overcome the current challenges.

  6. Capital Humano e Desenvolvimento Econômico no Rio Grande do Sul. Uma Abordagem Multivariada

    Directory of Open Access Journals (Sweden)

    Nilson Luiz Costa

    2017-01-01

    Full Text Available This article proposes an analysis from the theories linking human capital to economic development process. The method used consists of multivariate statistical techniques, particularly the Exploratory Factor Analysis and Conglomerates Analysis. Statistics were selected from 496 municipalities in the state of Rio Grande do Sul/Brazil according to their capacity to represents the dynamics of income concentration, quality of education and health, poverty, education and formal work. Among the results, there is a positive and direct association between levels of formal education and economic develop- ment, which validates the theoretical contributions of Theodore William Schultz and other authors that stem from their lineage. The results point to the importance of breaking the current paradigms and think education policy beyond the rhetoric of official speeches and overcome the current challenges.

  7. An international borderland of concern: Conservation of biodiversity in the Lower Rio Grande Valley

    Science.gov (United States)

    Leslie,, David M.

    2016-07-20

    The Lower Rio Grande Valley (LRGV) of southern Texas is located on the United States-Mexico borderland and represents a 240-kilometer (150-mile) linear stretch that ends at the Gulf of Mexico. The LRGV represents a unique transition between temperate and tropical conditions and, as such, sustains an exceptionally high diversity of plants and animals—some of them found in few, or no other, places in the United States. Examples include Leopardus pardalis albescens (northern ocelot) and Falco femoralis septentrionalis (northern aplomado falcon)—both endangered in the United States and emblematic of the LRGV. The U.S. Fish and Wildlife Service (USFWS) manages three national wildlife refuges (Santa Ana, Lower Rio Grande Valley, and Laguna Atascosa) that together make up the South Texas Refuge Complex, which actively conserves biodiversity in about 76,006 hectares (187,815.5 acres) of native riparian and upland habitats in the LRGV. These diminished habitats harbor many rare, threatened, and endangered species. This report updates the widely used 1988 USFWS biological report titled “Tamaulipan Brushland of the Lower Rio Grande Valley of South Texas: Description, Human Impacts, and Management Options” by synthesizing nearly 400 peer-reviewed scientific publications that have resulted from biological and sociological research conducted specifically in the four Texas counties of the LRGV in the past nearly 30 years. This report has three goals: (1) synthesize scientific insights gained since 1988 related to the biology and management of the LRGV and its unique biota, focusing on flora and fauna of greatest conservation concern; (2) update ongoing challenges facing Federal and State agencies and organizations that focus on conservation or key natural resources in the LRGV; and (3) redefine conservation opportunities and land-acquisition strategies that are feasible and appropriate today, given the many new and expanding constraints that challenge conservation

  8. Birds of the Reserva Biológica do Mato Grande and surroundings, Rio Grande do Sul, Brazil

    DEFF Research Database (Denmark)

    Vizentin-Bugoni, Jeferson; Jacobs, Fernando; Coimbra, Marco Antônio Afonso

    2015-01-01

    The Reserva Biológica do Mato Grande encompasses 5,161 hectares of wetlands, restinga forests and grasslands in southern Brazil. Aiming to assemble a list of bird species occurring in the reserve, we carried out 21 monthly expeditions from July 2007 to March 2009 and an additional visit on October...

  9. Overview of natural gas in Rio Grande do Norte, Brazil; Panorama do gas natural no Rio Grande do Norte

    Energy Technology Data Exchange (ETDEWEB)

    Teixeira, Pedro Helio Gomes [Universidade Federal do Rio Grande do Norte (GREEN/UFRN), Natal, RN (Brazil). Centro de Tecnologia. Grupo de Estudos Energeticos

    2008-07-01

    This work draws a picture of what the natural gas means to Rio Grande do Norte in its quantitative dimension, expressed in the numbers and reserve indicators, production and structure of consume. In another dimension, it broaches the processes of energetic substitution by the natural gas in the state energetic matrix. (author)

  10. Environmental challenge

    International Nuclear Information System (INIS)

    Conable, B.; Warford, J.; Partow, Z.; Lutz, E.; Munasinghe, M.

    1991-09-01

    The contents include the following: Development and the Environment: A Global Balance; Evolution of the World Bank's Environmental Policy; Accounting for the Environment; Public Policy and the Environment; Managing Drylands; Environmental Action Plans in Africa; Agroforestry in Sub-Saharan Africa; Irrigation and the Environmental Challenge; Curbing Pollution in Developing Countries; Global Warming and the Developing World; and The Global Environment Facility

  11. Challenging Identities

    DEFF Research Database (Denmark)

    depends on the conceptual or ideological constellation in which it takes part. This volume on one hand demonstrates the role of notions of identity in a variety of European contexts, and on the other hand highlights how there may be reasons to challenge the use of the term and corresponding social...

  12. Overcoming challenges

    Medline Plus

    Full Text Available ... Contact Us Blog Popular topics Vision and mission Leadership Programs and activities In your community Funding opportunities Internships and jobs View all pages in this section Home It's Only Natural Overcoming challenges It's Only Natural Planning ahead Addressing breastfeeding myths ...

  13. Overcoming challenges

    Medline Plus

    Full Text Available ... we are What we do Programs and activities Work with us Contact Us Blog Popular topics Vision and mission Leadership Programs and activities In your community Funding opportunities Internships and jobs View all pages in this section Home It's Only Natural Overcoming challenges It's Only Natural ...

  14. Assessing Grand Strategies: How the EU and NATO Rock the Strategic Boat

    Science.gov (United States)

    2015-05-01

    part to constitute the embryos of the European Union and NATO grand strategies briefly illustrated in the extracts presented in the epigraph. These... embryos gestated over time becoming de facto grand strategies for these institutions. Applying the characterization of grand strategy elaborated in...6. Michio Kaku, Physics of the Future: How Science Will Shape Human Destiny and Our Daily

  15. Water Environment Evolution along the China Grand Canal

    International Nuclear Information System (INIS)

    Mao, F; Wu, Y X; Yang, B F; Li, X J

    2014-01-01

    The China Grand Canal is one of the earliest canals in the world, having lasted for nearly 3000 years. Even its section canals have a rich history, such as the North-South Grand Canal that was established during the Sui Dynasty, whereas the Beijing-Hangzhou Canal was excavated during the Yuan Dynasty and the east line of the South-to-North Water Diversion. As one of the longest in the world, the China Grand Canal's total length is over 3500 kilometers. This length includes the navigable, unnavigable, and underground sections. Making the best use of situations and according to local conditions, the Chinese people harmoniously constructed the Beijing-Hangzhou Canal with nature. Tens of millions of workers took nearly 3000 years to complete the great shipping system. Navigable sections still exist for up to 900 kilometers and the volume of freight traffic is approximately 300 million tons. The canal remains the main logistical channel of the North-to-South Coal Transportation, South-to-North Water Diversion, and resources circulation. To date, China is promoting the success of heritage application. Part of these efforts is the declaration of the China Grand Canal as a World Cultural Heritage by 2014. In addition, the east route of the South-to-North Water Transfer project is planned to be navigable by 2016. The ancient Beijing-Hangzhou Grand Canal will usher in the new ecological civilization and cultural revival along the canal. This paper presents technical methods of water environment evolution research on the river system, river, and water quality along the Beijing-Hangzhou Canal through the integration of historical literature and modern remote sensing image data. The study carried out water environment investigation and analysis along the Beijing-Hangzhou canal by using ETM, SPOT image data, and GPS measurement data. Spatial and temporal evolution characteristics and regulations of the Beijing-Hangzhou Grand Canal regional water environment in the span of

  16. Mobility Challenges

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Lassen, Claus

    2011-01-01

    This article takes point of departure in the challenges to understand the importance of contemporary mobility. The approach advocated is a cross-disciplinary one drawing on sociology, geography, urban planning and design, and cultural studies. As such the perspective is to be seen as a part...... of the so-called ‘mobility turn’ within social science. The perspective is illustrative for the research efforts at the Centre for Mobility and Urban Studies (C-MUS), Aalborg University. The article presents the contours of a theoretical perspective meeting the challenges to research into contemporary urban...... mobilities. In particular the article discusses 1) the physical city, its infrastructures and technological hardware/software, 2) policies and planning strategies for urban mobility and 3) the lived everyday life in the city and the region....

  17. A Grand Vision for European Astronomy

    Science.gov (United States)

    2007-09-01

    Today, and for the first time, astronomers share their global Science Vision for European Astronomy in the next two decades. This two-year long effort by the ASTRONET network of funding agencies, sponsored by the European Commission and coordinated by INSU-CNRS, underscores Europe's ascension to world leadership in astronomy and its will to maintain that position. It will be followed in just over a year by a prioritised roadmap for the observational facilities needed to implement the Vision. Implementation of these plans will ensure that Europe fully contributes to Mankind's ever deeper understanding of the wonders of our Universe. astronet logo "This is a great opportunity to help create a vibrant long-term future for astronomy and science" says Tim de Zeeuw (Leiden Observatory, The Netherlands) who led this community-wide effort. The ASTRONET Science Vision provides a comprehensive overview of the most important scientific questions that European astronomy should address in the next twenty years. The four key questions are the extremes of the Universe, from the nature of the dark matter and dark energy that comprise over 95% of the Universe to the physics of extreme objects such as black holes, neutron stars, and gamma-ray bursts; the formation of galaxies from the first seeds to our Milky Way; the formation of stars and planets and the origin of life; and the crucial question of how do we (and our Solar System) fit in the global picture. These themes reach well beyond the realm of traditional astronomy into the frontiers of physics and biology. The Vision identifies the major new facilities that will be needed to achieve these goals, but also stresses the need for parallel developments in theory and numerical simulations, high-performance computing resources, efficient astronomical data archiving and the European Virtual Observatory, as well as in laboratory astrophysics. "This report is a key input for the even more challenging task of developing a prioritised

  18. Clinical Immersion and Biomedical Engineering Design Education: "Engineering Grand Rounds".

    Science.gov (United States)

    Walker, Matthew; Churchwell, André L

    2016-03-01

    Grand Rounds is a ritual of medical education and inpatient care comprised of presenting the medical problems and treatment of a patient to an audience of physicians, residents, and medical students. Traditionally, the patient would be in attendance for the presentation and would answer questions. Grand Rounds has evolved considerably over the years with most sessions being didactic-rarely having a patient present (although, in some instances, an actor will portray the patient). Other members of the team, such as nurses, nurse practitioners, and biomedical engineers, are not traditionally involved in the formal teaching process. In this study we examine the rapid ideation in a clinical setting to forge a system of cross talk between engineers and physicians as a steady state at the praxis of ideation and implementation.

  19. A Grande Reportagem em Televisão

    OpenAIRE

    Teixeira, Clara Manuela Araújo

    2009-01-01

    Monografia apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Ciências da Comunicação Este projecto de graduação é dedicado ao estudo da elaboração de uma grande reportagem em televisão. As próximas páginas procuram dar a conhecer ao leitor as diferentes fases do processo de realização de uma grande reportagem audiovisual: desde a preparação à investigação feita pelo jornalista, passando pela recolha de informação no terr...

  20. DOE-Grand Junction logging model data synopsis

    International Nuclear Information System (INIS)

    Mathews, M.A.; Koizumi, C.J.; Evans, H.B.

    1978-05-01

    This synopsis provides the available data concerning the logging models at the DoE-Grand Junction facility, to date (1976). Because gamma-ray logs are used in uranium exploration to estimate the grade (percent U 3 O 8 ) and the thickness of uranium ore zones in exploration drill holes, logging models are required to calibrate the gamma-ray logging equipment in order to obtain accuracy, uniformity, standardization, and repeatability during logging. This quality control is essential for accurate ore reserve calculations and for estimates of ore potential. The logging models at the DoE-Grand Junction facility are available for use by private industry in calibrating their gamma-ray logging equipment. 21 figures, 26 tables

  1. Standardized methods for Grand Canyon fisheries research 2015

    Science.gov (United States)

    Persons, William R.; Ward, David L.; Avery, Luke A.

    2013-01-01

    This document presents protocols and guidelines to persons sampling fishes in the Grand Canyon, to help ensure consistency in fish handling, fish tagging, and data collection among different projects and organizations. Most such research and monitoring projects are conducted under the general umbrella of the Glen Canyon Dam Adaptive Management Program and include studies by the U.S. Geological Survey (USGS), U.S. Fish and Wildlife Service (FWS), National Park Service (NPS), the Arizona Game and Fish Department (AGFD), various universities, and private contractors. This document is intended to provide guidance to fieldworkers regarding protocols that may vary from year to year depending on specific projects and objectives. We also provide herein documentation of standard methods used in the Grand Canyon that can be cited in scientific publications, as well as a summary of changes in protocols since the document was first created in 2002.

  2. Low-energy neutral current phenomenology and grand unified theories

    International Nuclear Information System (INIS)

    Del Aguila, F.; Mendez, A.

    1981-01-01

    We derive necessary and sufficient conditions to be satisfied by any expanded electroweak gauge model in order to reproduce the standard model low-energy neutral current predictions. These conditions imply several constraints on the neutral gauge boson masses and the quantum number assignments for the ordinary fermions. Using these conditions, we prove that the popular grand unified theories based on the gauge groups SO(10) and E6 can only accommodate trivial extensions of the standard model. As a consequence, if any of these grand unified models works at some energy scale, present low-energy neutral current phenomenology implies that the Z-boson must be produced with the expected mass and couplings to the ordinary fermions. Any additional neutral gauge boson (with the possible exception of very heavy ones) could only be produced in hadronic collisions and it would not decay in e + e - . (orig.)

  3. Bias Gender Dalam Novel La Grande Borne Karya NH. Dini

    OpenAIRE

    Dilla, Raili Irfa; Thahar, Harris Effendi; Zulfikarni, Zulfikarni

    2013-01-01

    The purpose of this article was to describe the gender diffraction in novel La Grande Borne by Nh. Dini, evaluated from five aspects, (a) marginalization, (b) subordination, (c) stereotype, (d) violence, and (e) double work load. The data of this study was the sentences that refer to the gender diffraction.. The analyze technics were (1) describe the data, (2) analyze the data that refer to gender, (3) lnterpretated the unfair in gender, and (4) conclusion. The results of this study could be ...

  4. L'espace mondial des grandes manifestations sportives internationales

    Directory of Open Access Journals (Sweden)

    Daniel MATHIEU

    1989-06-01

    Full Text Available La carte des grandes manifestations sportives mondiales montre une forte concentration des épreuves dans un petit nombre de pays développés, en particulier l'Europe occidentale. L'examen des nations concernées par les tournois majeurs du tennis et par le cyclisme professionnel soulignent, avec les nuances propres à chacun des sports, l'étroitesse des espaces intéressés.

  5. Magnetostratigraphy of the Grande Ronde Basalt Pasco Basin, Washington

    International Nuclear Information System (INIS)

    Packer, D.R.; Petty, M.H.

    1979-01-01

    The paleomagnetic measurements of samples from the holes sampled have shown that there are four magnetic correlation lines, between adjacent flows in holes that have distinctly different mean stratigraphic inclinations, and two magnetic polarity boundaries that can be used for magnetic correlation in the Grande Ronde Basalt in the Pasco Basin. The results of paleomagnetic measurements of samples from the Wanapum Basalt and Saddle Mountains Basalt indicate that the potential for magnetostratigraphic correlation in these sequences is also good

  6. Bitcoin Market Volatility Analysis Using Grand Canonical Minority Game

    Directory of Open Access Journals (Sweden)

    Matteo Ortisi

    2016-12-01

    Full Text Available In this paper we propose to use the Grand Canonical Minority Game (GCMG, a highly simplified financial market model as a model of bitcoin market to show how the lack of an income for “miners”, similar to yield earned by bond holders, could be a structural reason for high volatility of bitcoin price in a reference currency. Coherently with present analysis, the introduction of future contracts on bitcoin would have the effect of reducing the overall market volatility.

  7. Differential compaction mechanism for earth fissures near Casa Grande, Arizona.

    Science.gov (United States)

    Jachens, R.C.; Holzer, T.L.

    1982-01-01

    Precise gravity measurements indicate that earth fissures or tension cracks caused by ground-water withdrawal within a 10km2 area SE of Casa Grande are associated with relief on the buried interface between the alluvial aquifer and underlying bedrock. These relations suggest that the fissures are forming in response to localized differential compaction caused by localized variations of aquifer-system thickness. -from Authors

  8. Proceedings of the fourth workshop on grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Weldon, H.A.; Langacker, P.; Steinhardt, P.J.

    1983-01-01

    This book compiles the papers presented at the fourth conference of grand unified theories of nuclear physics held in University of Pennsylvania April 1983. The topics covered were proton decay theory; angular distribution and flux of atmospheric neutrinos; atmospheric neutrinos and astrophysical neutrinos in proton decay experiments; review of future nucleon decay experiments; monopole experiments; searches for magnetic monopole; monopoles, gauge, fields and anomalies; darkmatter, galaxies and voids; adiabatic fluctuations; supersymmetry, supergravity, and Kaluza-Klein theories; superstring theory and superunification.

  9. Radiative breaking of cosmologically acceptable grand unified theories

    International Nuclear Information System (INIS)

    Gato, B.; Leon, J.; Quiros, M.

    1984-01-01

    We present a cosmologically acceptable grand unified model where the breaking of SU(5) proceeds through radiative corrections induced by supergravity soft-breaking terms. The breaking scale is determined by dimensional transmutation. The model is compatible with the radiative breaking of SU(2)sub(L)xU(1)sub(Y) which provides an experimentally accessible low energy particle spectrum and small top quark mass. (orig.)

  10. Z2 vortex strings in grand unified theories

    International Nuclear Information System (INIS)

    Olive, D.; Turok, N.

    1982-01-01

    Spontaneously broken gauge theories may display distinct vortex string solutions for the disconnected components of the exact gauge symmetry group. A type of Higgs mechanism thought to apply in grand unified theories as being responsible for fermion masses yields Z 2 vortex lines, irrespectively of the group. These could seed galaxy formation if the corresponding fermion masses are superheavy. More generally a Higgs mechanism producing Zsub(n) vortex strings is presented. (orig.)

  11. Grande Ronde Basin Supplementation Program; Lostine River, 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Onjukka, Sam T. (Oregon Department of Fish and Wildlife, Portland, OR); Harbeck, Jim (Nez Perce Tribe, Department of Fisheries Resource Management, Enterprise, OR)

    2003-03-01

    The Northwest Power Planning Council (NPPC) identified supplementation as a high priority to achieve its goal of increasing runs of anadromous fish in the Columbia Basin. Supplementation activities in the Lostine River and associated monitoring and evaluation conducted by the Nez Perce Tribe relate directly to the needs addressed in the Columbia River Basin Fish and Wildlife Program (NPPC 1994). Measure 7.4L.1 of the Program mandates that appropriate research accompany any proposed supplementation. In addition, measure 7.3B.2 of the Program stresses the need for evaluating supplementation projects to assess their ability to increase production. Finally, Section 7.4D.3 encourages the study of hatchery rearing and release strategies to improve survival and adaptation of cultured fish. In 1997, Oregon Department of Fisheries and Wildlife (ODFW) requested a modification of Permit 1011 to allow the take of adult spring chinook salmon. In 1998, the Nez Perce Tribe also requested a permit specific to activities on Lostine River. The permit was issued in 2000. A special condition in the permits required the development of a long term management plan for the spring chinook salmon of the Grande Ronde Basin. The Nez Perce Tribe, ODFW, and the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) completed a formal long range plan entitled ''Grande Ronde Basin Endemic Spring Chinook Salmon Supplementation Program''. The program proposes to increase the survival of spring chinook salmon in the Grand Ronde Basin through hatchery intervention. Adult salmon from the Lostine River, Catherine Creek, and the Upper Grande Ronde River are used for a conventional supplementation program in the basin. The Nez Perce program currently operates under the ESA Section 10 Permit 1149.

  12. Grande Ronde Basin Supplementation Program; Lostine River, 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Onjukka, Sam T. (Oregon Department of Fish and Wildlife, Portland, OR); Harbeck, Jim (Nez Perce Tribe, Department of Fisheries Resource Management, Enterprise, OR)

    2003-03-01

    The Northwest Power Planning Council (NPPC) identified supplementation as a high priority to achieve its goal of increasing runs of anadromous fish in the Columbia Basin. Supplementation activities in the Lostine River and associated monitoring and evaluation conducted by the Nez Perce Tribe relate directly to the needs addressed in the Columbia River Basin Fish and Wildlife Program (NPPC 1994). Measure 7.4L.1 of the Program mandates that appropriate research accompany any proposed supplementation. In addition, measure 7.3B.2 of the Program stresses the need for evaluating supplementation projects to assess their ability to increase production. Finally, Section 7.4D.3 encourages the study of hatchery rearing and release strategies to improve survival and adaptation of cultured fish. In 1997, Oregon Department of Fisheries and Wildlife (ODFW) requested a modification of Permit 1011 to allow the take of adult spring chinook salmon. In 1998, the Nez Perce Tribe also requested a permit specific to activities on Lostine River. The permit was issued in 2000. A special condition in the permits required the development of a long term management plan for the spring chinook salmon of the Grande Ronde Basin. The Nez Perce Tribe, ODFW, and the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) completed a formal long range plan entitled ''Grande Ronde Basin Endemic Spring Chinook Salmon Supplementation Program''. The program proposes to increase the survival of spring chinook salmon in the Grand Ronde Basin through hatchery intervention. Adult salmon from the Lostine River, Catherine Creek, and the Upper Grande Ronde River are used for a conventional supplementation program in the basin. The Nez Perce program currently operates under the ESA Section 10 Permit 1149.

  13. Estimation of Actual Evapotranspiration along the Middle Rio Grande of New Mexico Using MODIS and Landsat Imagery with the METRIC Model

    OpenAIRE

    Trezza, Ricardo; Allen, Richard; Tasumi, Masahiro

    2013-01-01

    Estimation of actual evapotranspiration (ET) for the Middle Rio Grande valley in central New Mexico via the METRIC surface energy balance model using MODIS and Landsat imagery is described. MODIS images are a useful resource for estimating ET at large scales when high spatial resolution is not required. One advantage of MODIS satellites is that images having a view angle < ~15° are potentially available about every four to five days. The main challenge of applying METRIC using MODIS is the se...

  14. Deciphering solar magnetic activity: on grand minima in solar activity

    Energy Technology Data Exchange (ETDEWEB)

    McIntosh, Scott W. [High Altitude Observatory, National Center for Atmospheric Research, Boulder, CO (United States); Leamon, Robert J., E-mail: mscott@ucar.edu [Department of Physics, Montana State University, Bozeman, MT (United States)

    2015-07-08

    The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well- understood. There has been tremendous progress in the century since the discovery of solar magnetism—magnetism that ultimately drives the electromagnetic, particulate, and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a “grand minimum”? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(&ish) year solar activity cycle.

  15. United States Department of Energy, Grand Junction Office

    International Nuclear Information System (INIS)

    1980-01-01

    The Grand Junction Office (GJO), US Department of Energy (DOE), develops and administers programs for evaluating domestic uranium resources and the production capability of industry; for developing resource planning information for DOE; and for advancing geologic and geophysical exploration concepts and techniques. In addition, GJO administers the leasing of mineral lands under DOE control, and carries out activities relating to the environmental aspects of uranium mining and milling, including remedial programs. The Office is staffed by administrative and technical program-management personnel. Bendix Field Engineering Corporation (Bendix) is the DOE operating contractor at the Grand Junction, Colorado, Government-owned/contractor-operated (GOCO) facility. The technical staffs of both GJO and Bendix are primarily geoscience-oriented. Specifically during 1980, uranium resource assessment on 135 National Topographic Map Series (NTMS) quadrangles was completed, along with other specific studies, to yield October 1980 national resource estimates. In addition, updated uranium supply analysis and production capability projections were completed. Another key aspect of this successful program was the development of improved geophysical and geochemical equipment and techniques in support of uranium resource assessment. Much of the hardware and know-how developed was turned over to the public and to the uranium industry at large for application to uranium exploration and the assessment of uranium company resources. The Grand Junction Office also participated actively during 1980 in international cooperative research on uranium exploration techniques and on the geology of uranium deposits

  16. Light grand unified theory triplets and Yukawa splitting

    International Nuclear Information System (INIS)

    Rakshit, Subhendu; Shadmi, Yael; Raz, Guy; Roy, Sourov

    2004-01-01

    Triplet-mediated proton decay in grand unified theories (GUTs) is usually suppressed by arranging a large triplet mass. Here we explore instead a mechanism for suppressing the couplings of the triplets to the first and second generations compared to the Yukawa couplings, so that the triplets can be light. This mechanism is based on a 'triplet symmetry' in the context of product-group GUTs. We study two possibilities. The first possibility, which requires the top Yukawa coupling to arise from a nonrenormalizable operator at the GUT scale, is that all triplet couplings to matter are negligible, so that the triplets can be at the weak scale, giving new evidence for grand unification. The second possibility is that some triplet couplings, and in particular Ttb and Tt-barl-bar, are equal to the corresponding Yukawa couplings. This would give a distinct signature of grand unification if the triplets were sufficiently light. However, we derive a model-independent bound on the triplet mass in this case, which is at least 10 6 GeV. Finally, we construct an explicit viable GUT model based on Yukawa splitting, with the triplets at 10 14 GeV, as required for coupling unification to work. This model requires no additional thresholds below the GUT scale

  17. Deciphering Solar Magnetic Activity: On Grand Minima in Solar Activity

    Directory of Open Access Journals (Sweden)

    Scott William Mcintosh

    2015-07-01

    Full Text Available The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well understood. There has been tremendous progress in the century since the discovery of solar magnetism - magnetism that ultimately drives the electromagnetic, particulate and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a grand minimum? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(-ish year solar activity cycle.

  18. Deciphering Solar Magnetic Activity: On Grand Minima in Solar Activity

    Science.gov (United States)

    Mcintosh, Scott; Leamon, Robert

    2015-07-01

    The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well understood. There has been tremendous progress in the century since the discovery of solar magnetism - magnetism that ultimately drives the electromagnetic, particulate and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a "grand minimum"? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(-ish) year solar activity cycle.

  19. Blaise Cendrars et ses 'Grands Fétiches'

    DEFF Research Database (Denmark)

    Doubinsky, Sebastien

    2016-01-01

    Quand l’écrivain Blaise Cendrars fait paraître sa série de poèmes réunis sous le titre Les Grands Fétiches dans la revue bruxelloise Le Disque vert en 1922, il semble participer de la grande mode « Nègre » qui secoue la France en cette période. Co-découvreur des arts dits « primitives » dès 1916...... avec Guillaume Apollinaire, l’écrivain va les insérer dans son travail poétique comme miroirs inversés de la modernité occidentale. Cependant, même s'il utilise certains des clichés racistes de son époque, il se place lui-même dans le camp des « mélanophiles », et va se servir de cet Art Nègre pour...... repousser à l'extrême les frontières de la modernité. La série des Grands Fétiches participe directement de ce désir, et nous tenterons de montrer dans cet article comment ces objets dits primitifs deviennent des objets « instables » qui remettent en question la définition même du poétique....

  20. Lower Grande Ronde smolt trap monitoring. Annual report 1996

    International Nuclear Information System (INIS)

    Setter, A.; Carmichael, R.W.

    1998-01-01

    The authors sampled downstream migrating salmonids at Boggan's Oasis in the Grande Ronde River with a screw trap during 1995 and a scoop trap during 1996. Sampling began in March and terminated early in June. Wild spring chinook and wild/hatchery steelhead were collected and marked to assess migration patterns and timing. Fish were marked with tags in order to obtain downstream migration data with minimal fish handling. Observations were recorded when a fish swam through an interrogation monitor at hydroelectric facilities downstream. The second year for monitoring smolts leaving the Grande Ronde River was completed in 1995. The authors continued to pursue moving to a permanent location downstream for 1997 because of the limitations for trapping smolts at Boggan's Oasis. This involved reconnaissance surveys of several potential sites near the mouth of the river from 1994--1996. During February of 1996, a water velocity and bottom topography assessment was completed. Results of the assessment were used for siting the anchoring tower structure upstream approximately 1.2 miles from the mouth of the Grande Ronde River

  1. Global challenges

    International Nuclear Information System (INIS)

    Blix, H.

    1990-01-01

    A major challenge now facing the world is the supply of energy needed for growth and development in a manner which is not only economically viable but also environmentally acceptable and sustainable in view of the demands of and risks to future generations. The internationally most significant pollutants from energy production through fossil fuels are SO 2 and NO x which cause acid rain, and CO 2 which is the most significant contributor to the greenhouse effect. Nuclear power, now providing about 17% of the world's electricity and 5% of the primary energy already is making a notable contribution to avoiding these emissions. While the industrialized countries will need more energy and especially electricity in the future, the needs of the developing countries are naturally much larger and present a tremendous challenge to the shaping of the world's future energy supply system. The advanced countries will have to accept special responsibilities, as they can most easily use advanced technologies and they have been and remain the main contributors to the environmental problems we now face. Energy conservation and resort to new renewable energy sources, though highly desirable, appear inadequate alone to meet the challenges. The world can hardly afford to do without an increased use of nuclear power, although it is strongly contested in many countries. The objections raised against the nuclear option focus on safety, waste management and disposal problems and the risk for proliferation of nuclear weapons. These issues are not without their problems. The risk of proliferation exists but will not appreciably diminish with lesser global reliance on nuclear power. The waste issue is more of a political than a technical problem. The use of nuclear power, or any other energy source, will never be at zero risk, but the risks are constantly reduced by new techniques and practices. The IAEA sees it as one of its priority tasks to promote such techniques. (author)

  2. DARPA, SDI, and GaAs

    International Nuclear Information System (INIS)

    Karp, S.; Rooslid, S.

    1986-01-01

    When silicon replaced germanium in the early 1960's as the semiconductor of choice for solid state devices, it converted the entire industry in just a few years because of two important characteristics. First, silicon has a higher energy bandgap, which permits silicon-based devices to operate over a wider temperature range (a feature especially important to the military). Second, and more important, silicon has a native oxide that provided for improved stability and planar, rather than mesa, type devices. Planar technology soon spawned integrated circuits. The integrated circuit in turn brought on the electronics revolution, allowing the complexity of circuits to increase by a factor of two every year (Moore's Law) and bringing us from single transistors to megabit memory chips

  3. Environmental assessment of facility operations at the U.S. Department of Energy Grand Junction Projects Office, Grand Junction, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    The US Department of Energy (DOE) has prepared a sitewide environmental assessment (EA) of the proposed action to continue and expand present-day activities on the DOE Grand Junction Projects Office (GJPO) facility in Grand Junction, Colorado. Because DOE-GJPO regularly proposes and conducts many different on-site activities, DOE decided to evaluate these activities in one sitewide EA rather than in multiple, activity-specific documents. On the basis of the information and analyses presented in the EA, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined by the National Environmental Policy Act (NEPA) of 1969. Therefore, preparation of an environmental impact statement is not required for facility operations, and DOE is issuing this Finding of No Significant Impact (FONSI).

  4. Environmental assessment of facility operations at the U.S. Department of Energy Grand Junction Projects Office, Grand Junction, Colorado

    International Nuclear Information System (INIS)

    1996-06-01

    The US Department of Energy (DOE) has prepared a sitewide environmental assessment (EA) of the proposed action to continue and expand present-day activities on the DOE Grand Junction Projects Office (GJPO) facility in Grand Junction, Colorado. Because DOE-GJPO regularly proposes and conducts many different on-site activities, DOE decided to evaluate these activities in one sitewide EA rather than in multiple, activity-specific documents. On the basis of the information and analyses presented in the EA, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined by the National Environmental Policy Act (NEPA) of 1969. Therefore, preparation of an environmental impact statement is not required for facility operations, and DOE is issuing this Finding of No Significant Impact (FONSI)

  5. Microbial contamination and chemical toxicity of the Rio Grande

    Directory of Open Access Journals (Sweden)

    Valles Adrian

    2004-04-01

    Full Text Available Abstract Background The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic activities, as well as differences in disposal regulations and enforcement increase the contamination potential of water supplies along the border region. Therefore, continuous and accurate assessment of the quality of water supplies is of paramount importance. The objectives of this study were to monitor water quality of the Rio Grande and to determine if any correlations exist between fecal coliforms, E. coli, chemical toxicity as determined by Botsford's assay, H. pylori presence, and environmental parameters. Seven sites along a 112-Km segment of the Rio Grande from Sunland Park, NM to Fort Hancock, TX were sampled on a monthly basis between January 2000 and December 2002. Results The results showed great variability in the number of fecal coliforms, and E. coli on a month-to-month basis. Fecal coliforms ranged between 0–106 CFU/100 ml while E. coli ranged between 6 to > 2419 MPN. H. pylori showed positive detection for all the sites at different times. Toxicity ranged between 0 to 94% of inhibition capacity (IC. Since values above 50% are considered to be toxic, most of the sites displayed significant chemical toxicity at different times of the year. No significant correlations were observed between microbial indicators and chemical toxicity. Conclusion The results of the present study indicate that the 112-Km segment of the Rio Grande river from Sunland Park, NM to Fort Hancock, TX exceeds the standards for contact recreation water on a continuous basis. In addition, the presence of chemical toxicity in most sites along the 112-Km segment indicates that water quality is an area of concern for the bi-national region. The presence of H. pylori adds to the potential health hazards of the Rio Grande. Since no

  6. Data Challenges

    CERN Multimedia

    McCubbin, N A

    Some two years ago we planned a series of Data Challenges starting at the end of 2001. At the time, that seemed to be comfortingly far in the future... Well, as the saying goes, doesn't time fly when you are having fun! ATLAS Computing is now deep in the throes of getting the first Data Challenge (DC0) up and running. One of the main aims of DC0 is to have a software 'release' in which we can generate full physics events, track all particles through the detector, simulate the detector response, reconstruct the event, and study it, with appropriate data storage en route. As all software is "always 95% ready" (!), we have been able to do most of this, more or less, for some time. But DC0 forces us to have everything working, together, at the same time: a reality check. DC0 should finish early next year, and it will be followed almost immediately afterwards by DC1 (DC0 was foreseen as the 'check' for DC1). DC1 will last into the middle of 2002, and has two major goals. The first is generation, simulation, and r...

  7. Micetomas actinomicóticos no Rio Grande do Sul: relato de quatro casos Actinomycotic mycetomas in Rio Grande do Sul: report of 4 cases

    Directory of Open Access Journals (Sweden)

    Alberto T. Londero

    1986-03-01

    Full Text Available São relatados quatro casos de micetoma causados por Nocardia brasiliensis, ocorridos no Rio Grande do Sul. É revista a literatura rio-grandense-do-sul.Four cases of mycetoma caused by N. brasiliensis, occurring in Rio Grande do Sul (Brazil, are reported.

  8. Challenging makerspaces

    DEFF Research Database (Denmark)

    Sandvik, Kjetil; Thestrup, Klaus

    This paper takes its departure in the EU-project MakEY - Makerspaces in the early years – enhancing digital literacy and creativity that is part of a H2020 RISE-program and is running January 2017 - June 2019. Here digital literacy and creative skills of young children between the age of 3......-8 will be developed through participation in creative activities in specially-designed spaces termed ‘makerspaces’. This paper discusses, develops and challenges this term in relation to Danish pedagogical traditions, to expanding makerspaces onto the internet and on how to combine narratives and construction....... The Danish part of the project will be undertaken by a small network of partners: DOKK1, a public library and open urban space in Aarhus, that is experimenting with different kind of makerspaces, spaces and encounters between people, The LEGO-LAB situated at Computer Science, Aarhus University, that has...

  9. Pathogenic landscape of transboundary zoonotic diseases in the Mexico-US border along the Rio Grande

    Directory of Open Access Journals (Sweden)

    Maria Dolores Esteve-Gasent

    2014-11-01

    Full Text Available Transboundary zoonotic diseases, several of which are vector borne, can maintain a dynamic focus, and have pathogens circulating in geographic regions encircling multiple geopolitical boundaries. Global change is intensifying transboundary problems including the spatial variation of the risk and incidence of zoonotic diseases. The complexity of these challenges can be greater in areas where rivers delineate international boundaries and encompass transitions between ecozones. The Rio Grande serves as a natural border between the US State of Texas and the Mexican States of Chihuahua, Coahuila, Nuevo León, and Tamaulipas. Not only millions of people live in this transboundary region but also a substantial movement of goods and people pass through it everyday. Moreover, it occurs over a region that functions as a corridor for animal migrations, and thus links the Neotropic and Nearctic biogeographic zones, with the latter being a known foci of zoonotic diseases. However, the pathogenic landscape of important zoonotic diseases in the south Texas-Mexico transboundary region remains to be fully understood. An international perspective on the interplay between disease systems, ecosystem processes, land use, and human behaviors is applied here to analyze landscape and spatial features of Venezuelan equine encephalitis, Hantavirus disease, Lyme Borreliosis, Leptospirosis, Bartonellosis, Chagas disease, human Babesiosis, and Leishmaniasis. Surveillance systems following the One Health approach with a regional perspective will help identifying opportunities to mitigate the health burden of those diseases on human and animal populations. It is proposed that the Mexico-US border, along the Rio Grande region be viewed as a continuum landscape where zoonotic pathogens circulate regardless of national borders.

  10. Pathogenic Landscape of Transboundary Zoonotic Diseases in the Mexico–US Border Along the Rio Grande

    Science.gov (United States)

    Esteve-Gassent, Maria Dolores; Pérez de León, Adalberto A.; Romero-Salas, Dora; Feria-Arroyo, Teresa P.; Patino, Ramiro; Castro-Arellano, Ivan; Gordillo-Pérez, Guadalupe; Auclair, Allan; Goolsby, John; Rodriguez-Vivas, Roger Ivan; Estrada-Franco, Jose Guillermo

    2014-01-01

    Transboundary zoonotic diseases, several of which are vector borne, can maintain a dynamic focus and have pathogens circulating in geographic regions encircling multiple geopolitical boundaries. Global change is intensifying transboundary problems, including the spatial variation of the risk and incidence of zoonotic diseases. The complexity of these challenges can be greater in areas where rivers delineate international boundaries and encompass transitions between ecozones. The Rio Grande serves as a natural border between the US State of Texas and the Mexican States of Chihuahua, Coahuila, Nuevo León, and Tamaulipas. Not only do millions of people live in this transboundary region, but also a substantial amount of goods and people pass through it everyday. Moreover, it occurs over a region that functions as a corridor for animal migrations, and thus links the Neotropic and Nearctic biogeographic zones, with the latter being a known foci of zoonotic diseases. However, the pathogenic landscape of important zoonotic diseases in the south Texas–Mexico transboundary region remains to be fully understood. An international perspective on the interplay between disease systems, ecosystem processes, land use, and human behaviors is applied here to analyze landscape and spatial features of Venezuelan equine encephalitis, Hantavirus disease, Lyme Borreliosis, Leptospirosis, Bartonellosis, Chagas disease, human Babesiosis, and Leishmaniasis. Surveillance systems following the One Health approach with a regional perspective will help identifying opportunities to mitigate the health burden of those diseases on human and animal populations. It is proposed that the Mexico–US border along the Rio Grande region be viewed as a continuum landscape where zoonotic pathogens circulate regardless of national borders. PMID:25453027

  11. Think first job! Preferences and expectations of engineering students in a French `Grande Ecole'

    Science.gov (United States)

    Gerwel Proches, Cecile N.; Chelin, Nathalie; Rouvrais, Siegfried

    2018-03-01

    A career in engineering may be appealing owing to the prospect of a good salary and a dynamic work environment. There may, however, be challenges for students wishing to enter their first job. In engineering education, career preparation courses may be included so as to prepare students adequately for their first job, future careers, and to reinforce career decision-making skills. This study explored the first-job preferences and expectations of engineering students at a generalist French 'Grande Ecole' before their compulsory internship. The study ultimately provided insight into ways in which future engineers may best be equipped for their first jobs. A qualitative research study was employed, using four focus groups to collect data, which was analysed thematically. Key findings indicate the resolute importance that engineering students place on having a challenging job, teamwork, independence, opportunities for development, and a participative style of being managed. The research findings may be of value in order to renew an engineering curriculum with better alignment between students' expectations and industry needs.

  12. UMTRA project water sampling and analysis plan, Grand Junction, Colorado

    International Nuclear Information System (INIS)

    1994-07-01

    Surface remedial action will be completed at the Grand Junction processing site during the summer of 1994. Results of 1993 water sampling indicate that ground water flow conditions and ground water quality at the processing site have remained relatively constant with time. Uranium concentrations in ground water continue to exceed the maximum concentration limits, providing the best indication of the extent of contaminated ground water. Evaluation of surface water quality of the Colorado River indicate no impact from uranium processing activities. No compliance monitoring at the Cheney disposal site has been proposed because ground water in the Dakota Sandstone (uppermost aquifer) is classified as limited-use (Class 111) and because the disposal cell is hydrogeologically isolated from the uppermost aquifer. The following water sampling and water level monitoring activities are planned for calendar year 1994: (i) Semiannual (early summer and late fall) sampling of six existing monitor wells at the former Grand Junction processing site. Analytical results from this sampling will be used to continue characterizing hydrogeochemical trends in background ground water quality and in the contaminated ground water area resulting from source term (tailings) removal. (ii) Water level monitoring of approximately three proposed monitor wells projected to be installed in the alluvium at the processing site in September 1994. Data loggers will be installed in these wells, and water levels will be electronically monitored six times a day. These long-term, continuous ground water level data will be collected to better understand the relationship between surface and ground water at the site. Water level and water quality data eventually will be used in future ground water modeling to establish boundary conditions in the vicinity of the Grand Junction processing site. Modeling results will be used to help demonstrate and document the potential remedial alternative of natural flushing

  13. Pacing of Paleozoic macroevolutionary rates by Milankovitch grand cycles.

    Science.gov (United States)

    Crampton, James S; Meyers, Stephen R; Cooper, Roger A; Sadler, Peter M; Foote, Michael; Harte, David

    2018-05-29

    Periodic fluctuations in past biodiversity, speciation, and extinction have been proposed, with extremely long periods ranging from 26 to 62 million years, although forcing mechanisms remain speculative. In contrast, well-understood periodic Milankovitch climate forcing represents a viable driver for macroevolutionary fluctuations, although little evidence for such fluctuation exists except during the Late Cenozoic. The reality, magnitude, and drivers of periodic fluctuations in macroevolutionary rates are of interest given long-standing debate surrounding the relative roles of intrinsic biotic interactions vs. extrinsic environmental factors as drivers of biodiversity change. Here, we show that, over a time span of 60 million years, between 9 and 16% of the variance in biological turnover (i.e., speciation probability plus species extinction probability) in a major Early Paleozoic zooplankton group, the graptoloids, can be explained by long-period astronomical cycles (Milankovitch "grand cycles") associated with Earth's orbital eccentricity (2.6 million years) and obliquity (1.3 million years). These grand cycles modulate climate variability, alternating times of relative stability in the environment with times of maximum volatility. We infer that these cycles influenced graptolite speciation and extinction through climate-driven changes to oceanic circulation and structure. Our results confirm the existence of Milankovitch grand cycles in the Early Paleozoic Era and show that known processes related to the mechanics of the Solar System were shaping marine macroevolutionary rates comparatively early in the history of complex life. We present an application of hidden Markov models to macroevolutionary time series and protocols for the evaluation of statistical significance in spectral analysis.

  14. Glomar challenger

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, J P

    1969-01-01

    The Glomar Challenger has a length of 400 ft, a 65-ft beam, and a depth of 27 ft 6-in. She has a draft of 20 ft with a gross displacement of 10,500 long tons. The principal specifications of the vessel are tabulated. To achieve dynamic positioning, 4 fixed thrusters and the vessel's 2 propulsion screws are utilized. The ''fix'' is obtained by placing a sonar beacon, with self contained batteries, on the ocean floor at a selected site. The vessel is provided with 4 hydrophones installed in the hull at the 4 corners of a square. The sonar beacon radiates sound waves at a fixed pulse rate. If the vessel is directly over the beacon, the sound waves will arrive at all hydrophones simultaneously. A difference in time of arrival indicates the vessel is off location. The sound signals received by the hydrophones are fed into a computer. They are changed into coordinate information, which serves as the primary function of determining corrective action by the vessel's propulsion and thruster system. The computer feeds back information into a control system, which enables the propulsion and thrusters to automatically respond, in order to keep the vessel on the predetermined location. The major drilling components are listed. The deep-sea drilling project is described. A summary of the first leg is given in tabular form.

  15. Scrapheap Challenge

    CERN Document Server

    2004-01-01

    Three British guys at CERN recently took a break from work to try their hand at Scrapheap Challenge. Shown on Channel 4 in the UK, it is a show where two teams must construct a machine for a specific task using only the junk they can scavenge from the scrap yard around them. And they have just 10 hours to build their contraption before it is put to the test. The first round, aired 19 September, pitted a team of three women, from the British Army's Royal Electrical and Mechanical Engineers, against the CERN guys - the Up 'n Atoms: Ali Day, David McFarlane and James Ridewood. Each team, with the help of an appointed expert, had the task of making a giant, 3-metre self-propelled "bowling ball", to roll down a 50 metre bowling alley at skittles 4 metres high. The Up 'n Atoms' contraption featured a small car with a huge wheel on its back. Once up to speed, slamming on the brakes caused the wheel to roll over and take the car with it. On their very last run they managed to take out seven pins. Luckily, though, ...

  16. Information Summary, Area of Concern: Grand Calumet River, Indiana

    Science.gov (United States)

    1991-03-01

    Page 179-183) 56 Waste Fill and Lagoon Sites Mapped Within the Grand Calumet Watershed (Source R13, Table 2-15) 57 Waste Fills of Greatest Concern...Percent Response for Single Species Sediment Bioassays from Indiana Harbor (Source RI, Table 18) 78 Aquatic Macroinvertebrates Collected from Stations 1, 2...3, 4, 5, and 12a, 3-4 May 88 (Source Rl, Table 22) 79 Aquatic Macroinvertebrates Collected from Stations 6, 7, 8, 9a, 10a, and 11, 3-4 and 19 May 88

  17. Igreja e italianidade: Rio Grande do Sul (1875-1945

    Directory of Open Access Journals (Sweden)

    Paulo César Possamai

    1999-12-01

    Full Text Available This article analyses the position adopted by the catholic clergy concerning the italianità policy among the Italian immigrants in the State of Rio Grande do Sul. While the Carlists protected the Italian nationalism among the colonists and were inclined to a good relationship between the Catholic Church and the Kingdom of Italy, to the Capuchins the italianità was useful to preserve the catholic faith among the colonists, although they also supported the conservative point of view of the Vatican, that the liberal Italian State was the usurper of the papacy lands.

  18. GRAND DESIGN MODEL PEMBINAAN PROFESIONAL GURU BERBASIS DETERMINAN KINERJA GURU

    Directory of Open Access Journals (Sweden)

    Bambang Budi Wiyono

    2015-08-01

    Full Text Available Abstract: A Grand Design Model of Teacher Professional Education Based on Teacher's Perfor­mace Determinant. One of the crucial factors that determines the quality of education is teachers. Thus, developing teachers' professionalism in carrying out their work is essential. This study aims at developing a grand design model of teacher professional education based on determinant factors of teachers' performance. It is a research and development study (R&D, in which data were collected through questionnaires, observations, and interviews, and analyzed using descriptive statistics, correla­tion analysis, and qualitative data analysis. The sample consists of 90 teachers and 28 headmasters selected using quota random sampling. The findings of the study show that the effective model of teacher pro­fessional education is the one conducted through five steps, namely, needs analysis, development of training and supervision programs, implementation of the programs, evaluation of the programs, and follow-ups of the programs. The development of the programs requires coordination among related in­stitutions. The implementation needs to refer to the right principles, approach, and training techniques and be supported by good facilities, media, trainers, and training places. Keywords: training model, teachers' professionalism, teachers' performance Abstrak: Grand Design Model Pembinaan Profesional Guru Berbasis Determinan Kinerja Guru. Salah satu faktor yang sangat menentukan mutu pendidikan adalah guru. Untuk itu diperlukan pening­katan profesionalisme guru dalam melaksanakan tugas. Penelitian ini bertujuan mengembangkan grand design model pembinaan profesional guru yang efektif berbasis faktor-faktor determinan kinerja guru. Penelitian menggunakan desain penelitian pengembangan. Sampel diambil sebesar 90 guru dan 28 kepala sekolah dengan quota random sampling. Data dikumpulan data kuesioner, observasi, dan wawancara. Hasil pengumpulan data dianalisis

  19. Grande Ronde Endemic Spring Chinook Project - ODFW, 2008 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, Scott

    2009-04-10

    Core activities of the Grande Ronde Endemic Spring Chinook Supplementation Program (GRESCSP) are funded through the authority of the Lower Snake River Fish and Wildlife Compensation Plan (LSRCP). The LSRCP program was approved by the Water Resources Development Act of 1976, PL 94-587, Section 102, 94th Congress substantially in accordance with the Special Report, LSRCP, June 1975 on file with the Chief of Engineers. The LSRCP was prepared and submitted in compliance with the Fish and Wildlife Coordination Act of 1958, PL 85-624, 85th Congress, August 12, 1958 to mitigate for the losses of fish and wildlife caused by the construction of dams on lower Snake River. The GRESCSP is an artificial propagation program that was initiated by Bonneville Power Administrations Fish and Wildlife program in the mid 1990's. The intent of this program was to change the mitigation aspect of the LSRCP program (harvest mitigation) to an integrated supplementation program; inasmuch as, hatchery produced fish could be experimentally used as a recovery tool and fish surplus to mitigation would be available for in-place and in-kind harvest. Fish production is still authorized by the LSRCP with the original mitigation return goal of 5,860 adult spring Chinook to the project area. The GRESCSP was developed with two primary components: (1) conventional broodstock (projects 199800702; 199800703; 199800704) and (2) captive brood (projects 199801001; 199801006). The GRESCSP relies on cooperative M&E efforts from the LSRCP including setting aside the Wenaha and Minam tributaries as natural production reserves components used for reference streams. The GRESCSP, coordinated with federal and tribal partners, identifies production levels for both propagation components and weir management strategies for each of the three supplemented tributary areas within the Grande Ronde Sub-basin. The three supplemented areas are Catherine Creek, Lostine River, and upper Grande Ronde River. Lookingglass

  20. Los milagros de la Mamá Grande

    OpenAIRE

    Palomares Güells, Laura

    2017-01-01

    Análisis de la figura mítica de Carmen Balcells desde el arquetipo de "la Mamá Grande" con el que se la ha identificado en numerosas ocasiones, para observar la relevancia de Balcells en la memoria editorial colectiva del boom latinoamericano. Anàlisi de la figura mítica de Carmen Balcells des de l'arquetip de la "Mamà Gran" amb el que se l'ha identificat en nombroses ocasions per a observar la rellevància de Balcells en la memòria editorial col·lectiva del boom llatinoamericà.

  1. KLEPSUDRA: How the Rio Grande Treaty Increased Instability in Mexico

    Science.gov (United States)

    2008-05-09

    advantages, not the least of which is having an agency that can operate on the peer level with Mexico’s national water agency (Comisión Nacional del Agua ...Help Wanted’ ads,” USA Today, 25 April 08, sec. A, p. 8. 77 Manwaring (2007), 9-11, 24-25, 34-35. 78 Contamination levels along the border areas and in...the Rio Grande River after NAFTA has been extensively researched and documented. Recent testing indicates extreme fecal contamination is exposing

  2. Google Science Fair 2012 : Grand Prize Winner Brittany Wenger

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    17-18 age category AND Grand Prize Winner: Brittany Wenger (USA)—“Global Neural Network Cloud Service for Breast Cancer.” Brittany’s project harnesses the power of the cloud to help doctors accurately diagnose breast cancer. Brittany built an application that compares individual test results to an extensive dataset stored in the cloud, allowing doctors to assess tumors using a minimally-invasive procedure. Brittany Michelle Wenger, and her mother, passed through the CERN Control Centre accompanied by Mike Lamont, CERN Beams Department, Operation Group Leader.

  3. Softening the supersymmetric flavor problem in orbifold grand unified theories

    International Nuclear Information System (INIS)

    Kajiyama, Yuji; Terao, Haruhiko; Kubo, Jisuke

    2004-01-01

    The infrared attractive force of the bulk gauge interactions is applied to soften the supersymmetric flavor problem in the orbifold SU(5) grand unified theory of Kawamura. Then this force aligns in the infrared regime the soft supersymmetry breaking terms out of their anarchical disorder at a fundamental scale, in such a way that flavor-changing neutral currents as well as dangerous CP-violating phases are suppressed at low energies. It is found that this dynamical alignment is sufficiently good compared with the current experimental bounds, as long as the diagonalization matrices of the Yukawa couplings are CKM-like

  4. El poder de las grandes empresas petroleras: 19001950

    OpenAIRE

    Jesús Mora Contreras

    2003-01-01

    Entre 1900 y 1950 las grandes corporaciones petroleras internacionales lograron imponer a los propietarios del recurso natural en el Medio Oriente y en Venezuela las normas y procedimientos que regulaban contractual y legalmente las actividades de exploración y explotación de petróleo. Lograron además crear un cartel interna-cional de empresas productoras para dividirse el mercado entre ellas e imponer a los consumidores un sistema de fijación del precio mundial del crudo.

  5. Stability of mass hierarchy in locally supersymmetric grand unification

    International Nuclear Information System (INIS)

    Nishino, H.; Helayel-Neto, J.A.; Koh, I.G.

    1984-06-01

    Some locally supersymmetric SU(5) grand unified models with a sliding singlet and two pairs of 5sub(tilde) and 5sub(tilde)* Higgs multiplets are considered from the viewpoint of universal baryon asymmetry and the one-loop stability of mass hierarchy. A new mechanism based on ''sliding singlet reflection symmetry'' to avoid the problem of the mass hierarchical stability is proposed. The stability is shown up to two-loop levels for some models. All order stability is also discussed. (author)

  6. Grande Ronde Basin Fish Habitat Enhancement Project : 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, Vance R.; Powell, Russ M.; Stennfeld, Scott P.

    2001-04-01

    On July 1, 1984 the Bonneville Power Administration and the Oregon Department of Fish and Wildlife entered into an agreement to initiate fish habitat enhancement work in the Joseph Creek subbasin of the Grande Ronde River Basin in northeast Oregon. In July of 1985 the Upper and Middle Grande Ronde River, and Catherine Creek subbasins were included in the intergovernmental contract, and on March 1, 1996 the Wallowa River subbasin was added. The primary goal of ''The Grande Ronde Basin Fish Habitat Enhancement Project'' is to access, create, improve, protect, and restore riparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin. This project provided for implementation of Program Measure 703 (C)(1), Action Item 4.2 of the Northwest Power Planning Council's Columbia River Basin Fish and Wildlife Program (NPPC, 1987), and continues to be implemented as offsite mitigation for mainstem fishery losses caused by the Columbia River hydro-electric system. All work conducted by the Oregon Department of Fish and Wildlife is on private lands and therefore requires that considerable time be spent developing rapport with landowners to gain acceptance of, and continued cooperation with this program throughout 10-15 year lease periods. This project calls for passive regeneration of habitat, using riparian enclosure fencing as the primary method to restore degraded streams to a normative condition. Active remediation techniques using plantings, off-site water developments, site-specific instream structures, or whole channel alterations are also utilized where applicable. Individual projects contribute to and complement ecosystem and basin-wide watershed restoration efforts that are underway by state, federal, and tribal agencies, and local watershed councils. Work undertaken during 2000 included: (1) Implementing 2 new projects in the Grande Ronde drainage, and retrofitting one old

  7. Regulatory challenges

    International Nuclear Information System (INIS)

    Austvik, Ole Gunnar

    2003-01-01

    The problem for policy makers wanting to liberalize natural gas markets is that its concentrated structure may also be the socially most efficient one. Because of scale economies, more firms operating in the market may incur higher transportation costs unless the market grows sufficiently in each geographic segment. This argument goes for product extension through vertical (or horizontal) integration and the exploitation of economies of scope as well. Thus, the challenge for governments is to intervene in a way that preserves a market structure that has the potential to minimize cost, and at the same lime change its behavior in order to avoid possible lax cost control and exploitation of market power. The existence of scope advantages indicates that liberalization of the market should open for the possibility to bundle services in competition with provision of unbundled services. If operations are unbundled and there exist economies of scope, the gain from increased competition should be weighed against the losses of less efficient operations of each firm. Thus, with the growth in the European market, gradually more arguments support the idea of unbundling. The significant scale economy in trunk pipelines, sunk investments and capital immobility, possible economies of scope in vertical integration and companies' bundling of services influences vertical and horizontal ownership relations and contractual terms in the European gas market. In specific segments of the markets, these relationships may promote efficient investments and pricing without public interference, but the strong concentration of market power indicates that this is rather the exception than the rule. In order to design an efficient and welfare maximizing way of regulating the market one needs a closer identification of the actual goal of the regulation. Microeconomic theory is often used for this purpose. The author discusses the alternatives of laissez-faire, nationalization or regulation for the

  8. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    Science.gov (United States)

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C.; Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  9. The Tragedy of Migrants. Gabriele Del Grande's Reportage

    Directory of Open Access Journals (Sweden)

    Luigi Franchi

    2017-11-01

    Full Text Available L’espressione "Tragedia dei migranti" che ciclicamente compare nei notiziari televisivi, seppur evocando la categoria del tragico, non suscita nessuno dei sentimenti che caratterizzano questa forma di spettacolo. Lo spettatore infatti è portato a considerare i naufragi nel Mediterraneo il frutto di un destino ineluttabile, senza quindi intravedere alcuna possibilità da parte sua di intervenire sulla realtà. Mamadou va a morire e Il mare di mezzo di Gabriele Del Grande dimostrano come i naufragi dei migranti nel Mediterraneo non siano parte del disegno divino di un deus absconditus, ma una delle drammatiche conseguenze della crisi economica della contemporaneità. Esibendo i meccanismi sottesi al fenomeno della migrazione, l’autore mostra i presupposti razionali sui quali questa si fonda e suggerisce come i suoi esiti drammatici possano essere contrastati a livello individuale e collettivo. Questo articolo si propone di dotare di un senso più pieno l’espressione "tragedia dei migranti": per fare ciò si rintraccerà all’interno dei reportage la riemersione di alcuni topoi della tragedia greca. Verrà inoltre individuata tra gli individui incontrati da Del Grande nei suoi viaggi e i personaggi della tragedia greca una serie di analogie in grado di restituire alla condizione del migrante una reale potenzialità tragica.

  10. Grand Unification as a Bridge Between String Theory and Phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Pati, Jogesh C.

    2006-06-09

    In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2){sub L} x SU(2){sub R} x SU(4){sup c} or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in {mu} {yields} e{gamma}, {tau} {yields} {mu}{gamma}, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

  11. Geomorphology of plutonium in the Northern Rio Grande

    Energy Technology Data Exchange (ETDEWEB)

    Graf, W.L. [Arizona Univ., Tempe, AZ (United States). Dept., of Geography

    1993-03-01

    Nearly all of the plutonium in the natural environment of the Northern Rio Grande is associated with soils and sediment, and river processes account for most of the mobility of these materials. A composite regional budget for plutonium based on multi-decadal averages for sediment and plutonium movement shows that 90 percent of the plutonium moving into the system is from atmospheric fallout. The remaining 10 percent is from releases at Los Alamos. Annual variation in plutonium flux and storage exceeds 100 percent. The contribution to the plutonium budget from Los Alamos is associated with relatively coarse sediment which often behaves as bedload in the Rio Grande. Infusion of these materials into the main stream were largest in 1951, 1952, 1957, and 1968. Because of the schedule of delivery of plutonium to Los Alamos for experimentation and weapons manufacturing, the latter two years are probably the most important. Although the Los Alamos contribution to the entire plutonium budget was relatively small, in these four critical years it constituted 71--86 percent of the plutonium in bedload immediately downstream from Otowi.

  12. Cosmic Ray Physics with the KASCADE-Grande Observatory

    Science.gov (United States)

    Arteaga-Velázquez, J. C.; Apel, W. D.; Bekk, K.; Bertaina, M.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; Di Pierro, F.; Doll, P.; Engel, R.; Fuhrmann, D.; Gherghel-Lascu, A.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Huege, T.; Kampert, K.-H.; Kang, D.; Klages, H. O.; Link, K.; Łuczak, P.; Mathes, H. J.; Mayer, H. J.; Milke, J.; Mitrica, B.; Morello, C.; Oehlschläger, J.; Ostapchenko, S.; Pierog, T.; Rebel, H.; Roth, M.; Schieler, H.; Schoo, S.; Schröder, F. G.; Sima, O.; Toma, G.; Trinchero, G. C.; Ulrich, H.; Weindl, A.; Wochele, J.; Zabierowski, J.

    The existence of a knee at a few PeV in the all-particle cosmic ray energy spectrum has been well established by several experiments but its physical origin has eluded researches for a long time. It is believed that keys to disentangle the mystery could be found in the spectrum and the composition of cosmic rays between 1 PeV and 1 EeV. A first detailed look into the elemental chemical abundances of cosmic rays in this energy regime was provided by both the KASCADE and the KASCADE-Grande experiments. Their measurements opened the door to a wealth of new data on the subject, which led to the discovery of new structures in the all-particle energy spectrum and the confirmation of knee-like features in the spectra of individual mass groups, as well as the observation of an unexpected ankle-like structure at around 100 PeV in the flux of the light component of cosmic rays. In this contribution, early findings with the KASCADE-Grande experiment will be reviewed and then a short update on the analyses currently performed with the data of the observatory will be presented.

  13. Mandibular fracture cases in Pelotas, Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Rafael Silva da Silva

    2009-10-01

    Full Text Available Objectives: To analyze the data in the literature, which show a high incidence of mandibular fractures. The aim of this research was to elucidate the context in which these fractures occur among patients attended at the first aid center of “Pronto Socorro Municipal de Pelotas”, Rio Grande do Sul, Brazil. Methods: From the records referring to the period of June, 2001 to August, 2007, there were 1 345 patients with facial fractures. Of this total, 116 patients with mandibular fracture were selected for this study and the items analysed were: age, gender, mandibular fracture site, etiology and period of the year. Results: It was found that 86.2% of the sample were men. The most prevalent age was 20 to 29 years old representing 36.2%, and the most affected mandibular sites were the body, with 29 cases (25%, and the condyle, with 26 cases (22.4%. The most common cause of fractures was the physical aggression representing 37.1%. The period of the year with the highest incidence of mandibular fractures was the summer, with 38 cases (32.8%. Conclusion: It was therefore observed that the patients with mandibular fracture assisted at Pronto-Socorro Municipal de Pelotas, Rio Grande do Sul, Brazil, were generally men, 20 to 29 years old with mandibular body fracture and they were victims of physical aggression.

  14. Saturn's Magnetic Field from the Cassini Grand Finale orbits

    Science.gov (United States)

    Dougherty, M. K.; Cao, H.; Khurana, K. K.; Hunt, G. J.; Provan, G.; Kellock, S.; Burton, M. E.; Burk, T. A.

    2017-12-01

    The fundamental aims of the Cassini magnetometer investigation during the Cassini Grand Finale orbits were determination of Saturn's internal planetary magnetic field and the rotation rate of the deep interior. The unique geometry of the orbits provided an unprecedented opportunity to measure the intrinsic magnetic field at close distances never before encountered. The surprising close alignment of Saturn's magnetic axis with its spin axis, known about since the days of Pioneer 11, has been a focus of the team's analysis since Cassini Saturn Orbit Insertion. However, the varying northern and southern magnetospheric planetary period oscillations, which fill the magnetosphere, has been a factor in masking the field signals from the interior. Here we describe an overview of the magnetometer results from the Grand Finale orbits, including confirmation of the extreme axisymmetric nature of the planetary magnetic field, implications for knowledge of the rotation rate and the behaviour of external magnetic fields (arising from the ring current, field aligned currents both at high and low latitudes and the modulating effect of the planetary period oscillations).

  15. Wintertime Boundary Layer Structure in the Grand Canyon.

    Science.gov (United States)

    Whiteman, C. David; Zhong, Shiyuan; Bian, Xindi

    1999-08-01

    Wintertime temperature profiles in the Grand Canyon exhibit a neutral to isothermal stratification during both daytime and nighttime, with only rare instances of actual temperature inversions. The canyon warms during daytime and cools during nighttime more or less uniformly through the canyon's entire depth. This weak stability and temperature structure evolution differ from other Rocky Mountain valleys, which develop strong nocturnal inversions and exhibit convective and stable boundary layers that grow upward from the valley floor. Mechanisms that may be responsible for the different behavior of the Grand Canyon are discussed, including the possibility that the canyon atmosphere is frequently mixed to near-neutral stratification when cold air drains into the top of the canyon from the nearby snow-covered Kaibab Plateau. Another feature of canyon temperature profiles is the sharp inversions that often form near the canyon rims. These are generally produced when warm air is advected over the canyon in advance of passing synoptic-scale ridges.Wintertime winds in the main canyon are not classical diurnal along-valley wind systems. Rather, they are driven along the canyon axis by the horizontal synoptic-scale pressure gradient that is superimposed along the canyon's axis by passing synoptic-scale weather disturbances. They may thus bring winds into the canyon from either end at any time of day.The implications of the observed canyon boundary layer structure for air pollution dispersion are discussed.

  16. O DISCURSO DO MARKETING DE LUGAR E OS GRANDES EVENTOS

    Directory of Open Access Journals (Sweden)

    Michel Nicolau Netto

    Full Text Available Os grandes eventos se globalizam na mesma medida em que proliferam os lugares promovidos como marcas. Embora autônomos, esses processos estão relacionados ao se fundarem numa visão de que os lugares devem competir na globalização e que a competição deve se dar a partir de suas imagens. Esse tipo de competição se embasa num discurso produzido por publicitários de marketing de lugar, que tanto manuseiam formas simbólicas construídas como identidades coletivas, quanto se engajam na produção de novos elementos, de forma a configurá-los, tal qual as marcas de produtos, como diferencial competitivo. Neste artigo, investigo a atuação desses publicitários, compreendidos como artífices de um “senso comum planetário” que ressignifica a imagem do lugar a partir de concepção de uma marca. Serão aqui analisados os pressupostos desse discurso, suas instâncias de legitimidade e sua relação com os grandes eventos, que devem ser entendidos como espaços de consagração e circulação do discurso do marketing de lugar.

  17. Multivariable extrapolation of grand canonical free energy landscapes

    Science.gov (United States)

    Mahynski, Nathan A.; Errington, Jeffrey R.; Shen, Vincent K.

    2017-12-01

    We derive an approach for extrapolating the free energy landscape of multicomponent systems in the grand canonical ensemble, obtained from flat-histogram Monte Carlo simulations, from one set of temperature and chemical potentials to another. This is accomplished by expanding the landscape in a Taylor series at each value of the order parameter which defines its macrostate phase space. The coefficients in each Taylor polynomial are known exactly from fluctuation formulas, which may be computed by measuring the appropriate moments of extensive variables that fluctuate in this ensemble. Here we derive the expressions necessary to define these coefficients up to arbitrary order. In principle, this enables a single flat-histogram simulation to provide complete thermodynamic information over a broad range of temperatures and chemical potentials. Using this, we also show how to combine a small number of simulations, each performed at different conditions, in a thermodynamically consistent fashion to accurately compute properties at arbitrary temperatures and chemical potentials. This method may significantly increase the computational efficiency of biased grand canonical Monte Carlo simulations, especially for multicomponent mixtures. Although approximate, this approach is amenable to high-throughput and data-intensive investigations where it is preferable to have a large quantity of reasonably accurate simulation data, rather than a smaller amount with a higher accuracy.

  18. Predictive Temperature Equations for Three Sites at the Grand Canyon

    Science.gov (United States)

    McLaughlin, Katrina Marie Neitzel

    Climate data collected at a number of automated weather stations were used to create a series of predictive equations spanning from December 2009 to May 2010 in order to better predict the temperatures along hiking trails within the Grand Canyon. The central focus of this project is how atmospheric variables interact and can be combined to predict the weather in the Grand Canyon at the Indian Gardens, Phantom Ranch, and Bright Angel sites. Through the use of statistical analysis software and data regression, predictive equations were determined. The predictive equations are simple or multivariable best fits that reflect the curvilinear nature of the data. With data analysis software curves resulting from the predictive equations were plotted along with the observed data. Each equation's reduced chi2 was determined to aid the visual examination of the predictive equations' ability to reproduce the observed data. From this information an equation or pair of equations was determined to be the best of the predictive equations. Although a best predictive equation for each month and season was determined for each site, future work may refine equations to result in a more accurate predictive equation.

  19. Geomorphology of plutonium in the Northern Rio Grande

    International Nuclear Information System (INIS)

    Graf, W.L.

    1993-03-01

    Nearly all of the plutonium in the natural environment of the Northern Rio Grande is associated with soils and sediment, and river processes account for most of the mobility of these materials. A composite regional budget for plutonium based on multi-decadal averages for sediment and plutonium movement shows that 90 percent of the plutonium moving into the system is from atmospheric fallout. The remaining 10 percent is from releases at Los Alamos. Annual variation in plutonium flux and storage exceeds 100 percent. The contribution to the plutonium budget from Los Alamos is associated with relatively coarse sediment which often behaves as bedload in the Rio Grande. Infusion of these materials into the main stream were largest in 1951, 1952, 1957, and 1968. Because of the schedule of delivery of plutonium to Los Alamos for experimentation and weapons manufacturing, the latter two years are probably the most important. Although the Los Alamos contribution to the entire plutonium budget was relatively small, in these four critical years it constituted 71--86 percent of the plutonium in bedload immediately downstream from Otowi

  20. Grand Unification as a Bridge Between String Theory and Phenomenology

    Science.gov (United States)

    Pati, Jogesh C.

    In the first part of this paper, we explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity — be it string/M-theory or a reincarnation — this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2)L × SU(2)R × SU(4)c or SO(10) symmetry in 4D in explaining (i) observed neutrino oscillations, (ii) baryogenesis via leptogenesis, and (iii) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in μ → eγ, τ → μγ, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M-theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

  1. Grand Unification as a Bridge Between String Theory and Phenomenology

    International Nuclear Information System (INIS)

    Pati, J

    2006-01-01

    In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2) L x SU(2) R x SU(4) c or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in μ → eγ, τ → μγ, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism

  2. Measurement and reproduction accuracy of computer-controlled grand pianos

    Science.gov (United States)

    Goebl, Werner; Bresin, Roberto

    2003-10-01

    The recording and reproducing capabilities of a Yamaha Disklavier grand piano and a Bösendorfer SE290 computer-controlled grand piano were tested, with the goal of examining their reliability for performance research. An experimental setup consisting of accelerometers and a calibrated microphone was used to capture key and hammer movements, as well as the acoustic signal. Five selected keys were played by pianists with two types of touch (``staccato'' and ``legato''). Timing and dynamic differences between the original performance, the corresponding MIDI file recorded by the computer-controlled pianos, and its reproduction were analyzed. The two devices performed quite differently with respect to timing and dynamic accuracy. The Disklavier's onset capturing was slightly more precise (+/-10 ms) than its reproduction (-20 to +30 ms); the Bösendorfer performed generally better, but its timing accuracy was slightly less precise for recording (-10 to 3 ms) than for reproduction (+/-2 ms). Both devices exhibited a systematic (linear) error in recording over time. In the dynamic dimension, the Bösendorfer showed higher consistency over the whole dynamic range, while the Disklavier performed well only in a wide middle range. Neither device was able to capture or reproduce different types of touch.

  3. Probing the design of grand unification through conservation laws

    International Nuclear Information System (INIS)

    Pati, J.C.

    1981-01-01

    The purpose of this talk is to note a few special consequences of gauging ''maximal'' quark-lepton symmetries such as SO(16), which is the maximal symmetry for a single family of fermions. Within these symmetries, violations for B, L and F are spontaneous rather than explicit. Furthermore these symmetries as a rule permit intermediate mass scales approx.(10 3 -10 6 GeV) and (10 8 -10 11 GeV) filling the so-called grand plateau between 10 2 and 10 15 GeV. It has been shown in earlier papers that within these symmetries proton may decay via four alternative models: i.e. proton→one or three leptons or antileptons plus mesons; some of which can coexist. It is now observed that even n-n-bar oscillations can coexist with (B-L) conserving proton-decays of the type p→e + π 0 etc. without posing any conflict with the cosmological generation of baryon-excess; both these processes can possess measurable strengths so as to be amenable to forthcoming searches. Search for alternative decay modes of proton and n-n-bar oscillations, even as processes in second and third generation experiments, would provide valuable information on the question of intermediate mass-scales and thereby on the design of grand unification

  4. Towards a grand deal on subsidies and climate change

    International Nuclear Information System (INIS)

    Moor, Andre de

    2001-01-01

    Recent studies have identified public subsidies as a principal cause of unsustainable development. Worldwide, governments are spending up to $US950 billion a year on subsidies. Many of these public subsidies fail to serve their purpose and in fact, often turn out as policy failures as they further distort trade and cause environmental harm. The energy sector is among the most subsidized sectors in the world, receiving over $US240 billion per annum of public subsidies. This article highlights current energy subsidies and their implications. The article examines: (i) the global size and distribution of energy subsidies in industrialized and developing countries; (ii) the impact of these subsidies on the economy, equity and the environment ana their role as barriers for sustainable development; (iii) the political economy behind public subsidies and the various political and institutional barriers and lock-in mechanisms that cause subsidies to become entrenched in economic and public structures; and (iv) proposals for effective subsidy reform in energy policies, suggesting a global strategy to eliminate energy subsidies. OECD governments are in a position to take the lead, and the UN Framework Convention on Climate Change presents an excellent opportunity of striking a political grand deal and linking the reform of energy subsidies to a meaningful participation of developing countries to the Kyoto Protocol. Moreover, if sinks are to be included in the clean development mechanism (CDM), it is crucial to include the removal of forestry subsidies in the grand deal. (author)

  5. The New Totalitarians: Social Identities and Radical Islamist Political Grand Strategy

    National Research Council Canada - National Science Library

    Macdonald, Douglas J

    2007-01-01

    ... of the ideologically-driven grand political strategy of the Islamist extremists, which represents a totalitarian, transnational, and, in many versions, universalist social revolutionary movement...

  6. The Nature of Grand Minima and Maxima from Fully Nonlinear Flux Transport Dynamos

    Energy Technology Data Exchange (ETDEWEB)

    Inceoglu, Fadil; Arlt, Rainer [Leibniz-Institute for Astrophysics Potsdam, An der Sternwarte 16, D-14482, Potsdam (Germany); Rempel, Matthias, E-mail: finceoglu@aip.de [High Altitude Observatory, National Center for Atmospheric Research, P.O. Box 3000, Boulder, CO 80307 (United States)

    2017-10-20

    We aim to investigate the nature and occurrence characteristics of grand solar minimum and maximum periods, which are observed in the solar proxy records such as {sup 10}Be and {sup 14}C, using a fully nonlinear Babcock–Leighton type flux transport dynamo including momentum and entropy equations. The differential rotation and meridional circulation are generated from the effect of turbulent Reynolds stress and are subjected to back-reaction from the magnetic field. To generate grand minimum- and maximum-like periods in our simulations, we used random fluctuations in the angular momentum transport process, namely the Λ-mechanism, and in the Babcock–Leighton mechanism. To characterize the nature and occurrences of the identified grand minima and maxima in our simulations, we used the waiting time distribution analyses, which reflect whether the underlying distribution arises from a random or a memory-bearing process. The results show that, in the majority of the cases, the distributions of grand minima and maxima reveal that the nature of these events originates from memoryless processes. We also found that in our simulations the meridional circulation speed tends to be smaller during grand maximum, while it is faster during grand minimum periods. The radial differential rotation tends to be larger during grand maxima, while it is smaller during grand minima. The latitudinal differential rotation, on the other hand, is found to be larger during grand minima.

  7. Engineering assessment of inactive uranium mill tailings, Grand Junction site, Grand Junction, Colorado. Phase II, Title I

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-10-01

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Grand Junction, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.9 million tons of tailings at the Grand Junction site constitutes the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from millsite decontamination (Option I), to adding various depths of stabilization cover material (Options II and III), to removal of the tailings to long-term storage sites and decontamination of the present site (Options IV through VIII). Cost estimates for the eight options range from $470,000 to $18,130,000. Reprocessing the tailings for uranium recovery does not appear to be economically attractive at present.

  8. Engineering assessment of inactive uranium mill tailings, Grand Junction site, Grand Junction, Colorado. Phase II, Title I

    International Nuclear Information System (INIS)

    1977-10-01

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Grand Junction, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.9 million tons of tailings at the Grand Junction site constitutes the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from millsite decontamination (Option I), to adding various depths of stabilization cover material (Options II and III), to removal of the tailings to long-term storage sites and decontamination of the present site (Options IV through VIII). Cost estimates for the eight options range from $470,000 to $18,130,000. Reprocessing the tailings for uranium recovery does not appear to be economically attractive at present

  9. Jeito de mulher rural: a busca de direitos sociais e da igualdade de gênero no Rio Grande do Sul The rural woman's way: the struggle for social rights and gender equality in Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Alie Van Der Schaaf

    2003-01-01

    Full Text Available Este trabalho trata de processos emancipatórios de mulheres, em especial de pequenas agricultoras no sul do Brasil, no Movimento de Mulheres Trabalhadoras Rurais do Rio Grande do Sul - MMTR-RS. A vida diária das agricultoras nos providencia elementos cruciais para entender a sua ação social, sendo o âmbito em que se produzem os significados culturais. Além disso, o enfoque na vida diária revela o impacto dos contextos históricos, econômicos, religiosos e políticos específicos em que a ação social acontece e nos ajuda a entender como as participantes chegam a problematizar demandas coletivas e a desafiar a arena política.This work approaches womens' emancipatory processes, specially those by small farmers in Southern Brazil, within the Rural Working Women's Movement of Rio Grande do Sul - MMTR-RS. Rural working women's daily life provide us with crucial elements to understand their social action, as the field in which they produce cultural meaning. Besides, the focus on daily life reveals the impact of historical, economical, religious and political contexts in which action develops, and helps us to understand how participants identify a set of problems as collective demands and challenge public arena.

  10. Imaging mass spectrometry tackles interfacial challenges in electrochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Xiao-Ying

    2017-12-01

    Electrochemistry has played a significant role in many research fields. Owing to its sensitivity and selectivity, in situ electroanalysis has been widely used as a fast and economical means for achieving outstanding results. Although many spectroscopic techniques have been used in electrochemistry, the challenges to capture short-lived intermediate species as a result of electron transfer in the buried solid electrode and electrolyte solution interface remains a grand challenge. In situ imaging mass spectrometry (IMS) recently has been extended to capture transient species in electrochemistry. This review intends to summarize newest development of IMS and its applications in advancing fundamental electrochemistry.

  11. The 'New Urban Europe': Global Challenges and Local Responses in the Urban Century

    NARCIS (Netherlands)

    Nijkamp, P.; Kourtit, K.

    2013-01-01

    Modern cities in the open European space-economy are powerhouses of creative ideas, smart technologies, sustainable developments and socio-economic wealth. They play a pivotal role in the future of an urbanized Europe, but they are also confronted with grand challenges, notably far-reaching

  12. Completion of the uranium mill tailings remedial project and cleanup of the former mill site at Grand Junction, Colorado

    International Nuclear Information System (INIS)

    Rael, G.J.; Cox, S.W.; Artiglia, E.W.

    2000-01-01

    The United States Department of Energy's Uranium Mill Tailings Remedial Action (UMTRA) Surface Project has successfully completed the cleanup of 22 former uranium mill sites, more than 5400 vicinity properties, and has constructed 18 entombment cells. The Project has recently received the United States Nuclear Regulatory Commission's approval and certification for the last two disposal sites, with these sites being placed under the general license for long term custodial care of residual radioactive material. The UMTRA site located at Grand Junction, Colorado is a good example of the technical, political, economic, and public relations challenges that were overcome in achieving success. The UMTRA Team discussed, negotiated, planned, and eventually acted on this uranium mill tailings problem and brought the project to a successful conclusion for the community. From the early 1940s through the 1970s, uranium ore was mined in significant quantities under United States federal contracts for the government's national defence programmes, i.e. the Manhattan Engineering District and Atomic Energy Commission programmes. The problem started as the need for uranium decreased in the late 1960s, resulting in mills shutting down, leaving behind large quantities of process waste tailings and contaminated mill buildings. The former Climax Uranium Company mill site in Grand Junction was one of the largest of these sites. (author)

  13. Public safety around dams : Grand River Conservation Authority

    Energy Technology Data Exchange (ETDEWEB)

    Moore, N [Grand River Conservation Authority, Cambridge, ON (Canada)

    2009-07-01

    Ontario's Grand River Conservation Authority (GRCA) is a corporate body, through which municipalities, landowners and other organizations work cooperatively to manage the watershed and outdoor recreation. This involves reducing flood damage; improving water quality; providing adequate water supply; protecting natural areas; watershed planning; and environmental education. This presentation discussed public safety issues regarding a dam in the GRCA that is 5 minutes to downtown Brantford; 5 minutes to several elementary and secondary schools; and a popular area for anglers. The city of Brantford owns the east embankment and the Brant conservation area is located on the west embankment. The safeguards included measures to involve the municipality and local police; install better signage; install better fencing; and public education. Increasing public awareness of the dangers surrounding dams was an important point of the presentation. Results included reduced trespassing and greater community awareness. figs.

  14. Pre-cambrian geochronology in Rio Grande do Norte, Brazil

    International Nuclear Information System (INIS)

    Galindo, A.C.

    1981-08-01

    The Precambrian region polyciclic caracter, in the Rio Grande do Norte State has make difficulties to its geochronological and geological studies. Four importants tectonometamorphic occurences identified dissimulate the original isotopic composition of the rocks. Is much defined the presence of three geochronological events wich left vestiges in the differents Serido litological units. The first event is related with Jequie cicle (2,7 b.y) and related with the Caico Group rocks. The second important event define the Transamazonic cicle (2.1 b.y). The third is correlated with Brazilian Cicle, when occurred the granitoids and pegmatites bodies formation. This third event was the last in this region and affect the other units too. (C.D.G.) [pt

  15. Gauge hierarchy in an SO(10) supersymmetric grand unified model

    International Nuclear Information System (INIS)

    Zhiyong, Z.

    1982-01-01

    An SO(10) supersymmetric grand unified model is constructed in which the gauge hierarchy problem may be solved. Using Higgs superfields belonging to the SO(10) representations 16, 10 and 54, it is found that if SO(10) is broken down to SU(3)sub(c)xSU(2)sub(L)xU(1) via SO(6)xSO(4)approximately equal to SU(4)sub(c)xSU(2)sub(L)xSU(2)sub(R) at unification mass scales without supersymmetry breaking, the gauge hierarchy puzzle might be carried away. It is also shown that the colour-triplet Higgs, which mediates proton decay, is superheavy by an incredibly accurate, but 'natural' adjustment of parameters in the potential. (author)

  16. The Dialogical Traveler: A Reading of Semprun's Le grand voyage

    Directory of Open Access Journals (Sweden)

    Sally M. Silk

    1990-06-01

    Full Text Available In light of discourse theory influenced by Bakhtin's concept of dialogism, the notion of voice has changed significantly so that we are invited to read discourse in a way that represents a departure from Bakhtin. The theories of François Flahault, Michel Pêchetut, and John Frow, who inquire into the importance of conditions of production of language, are used to explore the vain search for a subject-centered voice in Jorge Semprun's Le Grand voyage . The narrating subject Gerard experiences "homelessness" in discourse because he fails to find a voice of his own. His relationship to music and literature depends on an other; in invasion of self by the other occurs so that Gerard speaks only through alien voices that confront him throughout the narrative. In discourse a decentering occurs that is not present at the thematic level: the protagonist arrives at a destination, but discourse does not.

  17. Leucemia de grandes linfócitos granulares

    OpenAIRE

    Terra,Bruno; Maia,Amanda M.

    2010-01-01

    O presente estudo tem como objetivo o estabelecimento de fundamentação teórica atualizada baseada em revisão bibliográfica sobre a leucemia de grandes linfócitos granulares (LGLG), doença onco-hematológica, que, devido à sua relativa raridade, é pouco conhecida e subdiagnosticada. A LGLG é caracterizada pela proliferação clonal de linfócitos T ou NK na medula óssea e/ou no sangue periférico. Dentre as manifestações clínico-laboratoriais, podem ocorrer citopenias (anemia e/ou neutropenia e/ou ...

  18. Reconciling grand unification with strings by anisotropic compactifications

    International Nuclear Information System (INIS)

    Dundee, Ben; Raby, Stuart; Wingerter, Akin

    2008-01-01

    We analyze gauge coupling unification in the context of heterotic strings on anisotropic orbifolds. This construction is very much analogous to effective five-dimensional orbifold grand unified theory field theories. Our analysis assumes three fundamental scales: the string scale M S , a compactification scale M C , and a mass scale for some of the vectorlike exotics M EX ; the other exotics are assumed to get mass at M S . In the particular models analyzed, we show that gauge coupling unification is not possible with M EX =M C , and in fact we require M EX C ∼3x10 16 GeV. We find that about 10% of the parameter space has a proton lifetime (from dimension six gauge exchange) 10 33 yr 0 e + ) 36 yr. The other 80% of the parameter space gives proton lifetimes below Super-Kamiokande bounds. The next generation of proton decay experiments should be sensitive to the remaining parameter space.

  19. Prevalence of canine parvovirus infection in Grand Tunis, Tunisia

    Directory of Open Access Journals (Sweden)

    Ghada Tagorti

    2018-03-01

    Results: The overall prevalence of CPV-2 was 32.14% (n=54/168. A total number of 54 young dogs, aging 1 to 7 months, of American Staffordshire terrier, German shepherd, Rottweiler and Spaniel breeds were affected. There was no sex predisposition and German shepherd was the over-represented breed (n=33/54; 61.11%. The prevalence of clinical cases below the three months old was 70.37% (n=38/54 with autumn (n=27/54; 50% as the most common season of infection. Furthermore, the study showed that 87.04% (n=47/54 of CPV-2 unvaccinated young dogs were positive. Conclusion: This work was a new descriptive study concerning canine parvovirus infection in the Grand Tunis; further studies are required to better characterize the epidemiology of CPV-2 infection in Tunisia. [J Adv Vet Anim Res 2018; 5(1.000: 93-97

  20. Big Bologna. Le anomalie degli spazi pubblici in grande scala

    Directory of Open Access Journals (Sweden)

    Richard Ingersoll

    2013-06-01

    Full Text Available Nella periferia di Bologna sono nati recentemente nuovi spazi pubblici, molto diversi rispetto a quelli della città storica, che esprimono chiaramente  la mania della grandezza, la sindrome di Big Bologna. Ovunque si getta lo sguardo si notano nuove manifestazioni di una scala fuori proporzione che contribuisce alla segregazione sociale. Da quando sono arrivate le torri bianche della megastruttura di Kenzo Tange alla Fiera, la grande scala ha dato origine a spazi pubblici poco ameni per la vita urbana. Forse questi megaprogetti sono inevitabili segni dell’epoca della globalizzazione, ma ci si chiede se i committenti e i loro architetti sono stati consapevoli di quanto la progettazione di tali forme causa un deterrente alla socializzazione.

  1. Brasil – Estados Unidos: grandes expectativas, pequenos atritos

    Directory of Open Access Journals (Sweden)

    Virgílio Caixeta Arraes

    2016-12-01

    Full Text Available O princípio da administração de Barack Obama, do Partido Democrata, gerou expectativa positiva na América Latina, região desdenhada pelo antecessor, George Bush, do Partido Republicano. Valorizar o continente seria prestigiar o Brasil. Todavia, o relacionamento não foi o esperado, embora sem grandes decepções também. The beginning of Barack Obama´s term produced positive expectations on Latin America, a continent which was ignored by his predecessor, George Bush. To give attention to Latin America implies giving prestige to Brazil.  Nonetheless the real relationship could not meet the expectations, although without causing great deceptions.

  2. O turning point da grande reportagem multimídia

    OpenAIRE

    Longhi, Raquel Ritter; Universidade Federal de Santa Catarina / Campus Reitor João David Ferreira Lima. Florianópolis, Santa Catarina. Brasil. CEP: 88049-900 Tel: (48) 3721.9000

    2015-01-01

    Este artigo analisa o estado da arte da grande reportagem multimídia no jornalismo online, atentando para um momento que se pode definir como “turning point”, ou ponto de virada desse tipo de formato noticioso. A partir de uma sistematização da evolução dos formatos expressivos multimidiáticos da notícia no jornalismo digital, o artigo identifica três momentos principais dessa trajetória: o slide-show noticioso, no início dos anos 2000; os especiais multimídia, de meados de 2000 a 2011 e a gr...

  3. Squark and slepton mass relations in grand unified theories

    International Nuclear Information System (INIS)

    Cheng, H.; Hall, L.J.

    1995-01-01

    In the minimal supersymmetric standard model, assuming universal scalar masses at large energies, there are four intragenerational relations between the masses of the squarks and sleptons for each light generation. In this paper we study the scalar mass relations which follow only from the assumption that at large energies there is a grand unified theory which leads to a significant prediction of the weak mixing angle. Two new intragenerational mass relations for each of the light generations are derived. In addition, a third mass relation is found which relates the Higgs boson masses, the masses of the third generation scalars, and the masses of the scalars of the lighter generations. Verification of a fourth mass relation, involving only the charged slepton masses, provides a signal for SO(10) unification

  4. Grande Ronde Basin Fish Habitat Enhancement Project : 2007 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, Vance R.; Morton, Winston H.

    2008-12-30

    On July 1, 1984 the Bonneville Power Administration and the Oregon Department of Fish and Wildlife entered into an intergovernmental contract to initiate fish habitat enhancement work in the Joseph Creek subbasin of the Grande Ronde River Basin in northeast Oregon. In 1985 the Upper and Middle Grande Ronde River, and Catherine Creek subbasins were included in the contract, and in 1996 the Wallowa River subbasin was added. The primary goal of 'The Grande Ronde Basin Fish Habitat Enhancement Project' is to create, protect, and restore riparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin. This project provided for implementation of Program Measure 703 (C)(1), Action Item 4.2 of the Northwest Power Planning Council's Columbia River Basin Fish and Wildlife Program (NPPC, 1987), and continues to be implemented as offsite mitigation for mainstem fishery losses caused by the Columbia River hydro-electric system. All work conducted by the Oregon Department of Fish and Wildlife and partners is on private lands and therefore requires that considerable time be spent developing rapport with landowners to gain acceptance of, and continued cooperation with this program throughout 10-15 year lease periods. Both passive and active restoration treatment techniques are used. Passive regeneration of habitat, using riparian exclosure fencing and alternate water sources are the primary method to restore degraded streams when restoration can be achieved primarily through changes in management. Active restoration techniques using plantings, bioengineering, site-specific instream structures, or whole stream channel alterations are utilized when streams are more severely degraded and not likely to recover in a reasonable timeframe. Individual projects contribute to and complement ecosystem and basin-wide watershed restoration efforts that are underway by state, federal, and tribal agencies, and

  5. Grand unification and the fundamental problems of classical cosmology

    International Nuclear Information System (INIS)

    Turner, M.S.

    1981-01-01

    The accomplishments of classical cosmology are reviewed. In particular, the hot big bang model provides a reliable framework for understanding the evolution of the universe back to times at least as early as approx. 0.01 s after the big bang. At present there are (at least) six fundamental problems which have not yet been (completely) resolved. They are: (1) the origin of the baryon number-to-entropy ratio, (2) the origin of the isotropy, (3) the origin of the homogeneity and inhomogeneity, (4) the origin of the flatness, (5) the cosmological constant, and (6) the monopole problem. The role that grand unification has played, and may play in the resolution of these puzzles is discussed. Guth's inflationary universe, which addresses five of these six problems, is reviewed

  6. Pattern of neutrino mixing in grand unified theories

    International Nuclear Information System (INIS)

    Milton, K.; Tanaka, K.

    1981-01-01

    It was found previously in SO(10) grand unified theories that if the neutrinos have a Dirac mass and a right-handed Majorana mass (approx. 10 15 GeV) but no left-handed Majorana mass, there is small ν/sub e/ mixing but ν/sub μ/ - ν/sub tau/ mixing can be substantial. This problem is reexamined on the basis of a formalism that assumes that the up, down, lepton, and neutrino mass matrices arise from a single complex 10 and a single 126 Higgs boson. This formalism determines the Majorana mass matrix in terms of quark mass matrices. Adopting three different sets of quark mass matrices that produce acceptable fermion mass ratios and Cabbibo mixing produces results consistent with the above; however, in the optimum case, ν/sub e/ - ν/sub μ/ mixing can be of the order of the Cabbibo angle

  7. STEM education for teachers in the Rio Grande Valley

    Science.gov (United States)

    Ries, Judit Gyorgyey; Baguio, Margaret R.

    2015-11-01

    We have worked with elementary and middle school teachers in the Rio Grande Valley for the last 10 years bringing Earth and Space Science themed workshops to underserved areas of Texas. The Texas curriculum was also changed to include Astronomy and Space Science requirement in the tests students need to take to prove their academic preparedness. The teachers worked through a variety of inquiry-based, hands-on activities after a short presentation on the background science. In order to evaluate our effectiveness, we have asked the teachers to take pre- and post-workshop tests, and we asked them to fill out a self-reflective survey. We will report on our experiences, what works best with the teachers, and in what areas we still have a long way to go.This work was supported by various NASA education grants and Cooperative agreements, as well as grants provided by the Texas Space Grant Consortium.

  8. RESCUE OF Cucurbita spp. GERMPLASM IN RIO GRANDE DO NORTE

    Directory of Open Access Journals (Sweden)

    GRACE KELLY LEITE DE LIMA

    2016-01-01

    Full Text Available Com objetivo de resgatar germoplasma de Cucurbita spp. da agricultura familiar do estado do Rio Grande do Norte, quantificar a variabilidade fenotípica e identificar as principais espécies cultivadas, foram organizadas 17 expedições para coleta de acessos, nos municípios de Baraúna, Rio do Fogo e Touros (principais fornecedores de frutos para o comercio estadual e de mais oito municípios de diferentes microrregiões do Estado (Apodi, Caraúbas, Ceará Mirim, Cerro Corá, Currais Novos, João Câmara, Lagoa Nova e Macaíba. Cada acesso coletado foi composto por um fruto ou aproximadamente vinte sementes fornecidas pelo próprio agricultor. Todos os acessos foram identificados quanto à espécie botânica e realizados os procedimentos de acondicionamento, identificação e armazenamento das sementes em câmara fria para preservação do material. Uma amostra dos acessos coletados como frutos e uma pequena parte dos acessos obtidos como sementes da espécie C. moschata foram multiplicados usando-se autofecundação das plantas. Plantas e frutos foram caracterizados preliminarmente com auxílio de descritores morfológicos. Resgatou-se acessos em todos os municípios visitados, sendo 112 de C. moschata e 50 de C. maxima. Verificou-se predominância do cultivo da espécie C. moschata bem como constatou-se grande variabilidade para vários descritores de planta e fruto nos acessos que foram caracterizados.

  9. QUALIDADE AMBIENTAL DO RESERVATÓRIO CAJÁ, TABOLEIRO GRANDE (RN

    Directory of Open Access Journals (Sweden)

    Francisco Ericardo do Nascimento

    2016-07-01

    Full Text Available O reservatório Cajá é o manancial responsável por abastecer a cidade de Taboleiro Grande mas, atualmente, sofre com alguns problemas relacionados ao uso e ocupação do entorno, além da diminuição do volume em função da baixa precipitação pluviométrica na região do Alto Oeste Potiguar. O objetivo deste trabalho foi realizar uma análise da qualidade ambiental do reservatório Cajá, localizado no município de Taboleiro Grande (RN. A metodologia de abordagem consistiu em leitura de parâmetros de qualidade de água com aparelho multiparâmetro, levantamento pontuais de impactos ambientais, e entrevistas com a população local sobre questões relacionadas ao uso e qualidade das águas do reservatório, tendo como principal foco a percepção ambiental dos munícipes. Os parâmetros utilizados para analisar a qualidade das águas foram: Temperatura, pH, Oxigênio Dissolvido e Condutividade Elétrica. Estabeleceram-se dois pontos no reservatório, onde as leituras foram realizadas em dois períodos sazonais, isto é, na estação seca e chuvosa. O resultado das análises mostrou que o OD e CE não apresentaram os índices estabelecidos pelo CONAMA 357/2005 para o consumo da água para o ser humano. Foram identificadas também algumas fontes que contribuem para a degradação da qualidade da água do manancial

  10. Stratigraphy of the Grande Savane Ignimbrite Sequence, Dominica, Lesser Antilles

    Science.gov (United States)

    Schneider, S.; Smith, A. L.; Deuerling, K.; Killingsworth, N.; Daly, G.

    2007-12-01

    The island of Dominica, located in the central part of the Lesser Antilles island arc has eight potentially active volcanoes. One of these, Morne Diablotins, is a composite stratovolcano with several superimposed stratigraphic sequences ranging in age from Pliocene (4-2 Ma) to "Younger" Pleistocene (22,000 and >40,000 years B.P. The ignimbrite sequences form four flow fans that reached both the east and west coasts of the island. One of these flow fans, the Grande Savane, on the west coast of the island, also extends off-shore for a distance of at least 14 km as a distinctive submarine fan. Stratigraphical studies of the on- shore deposits that make up this fan indicate an older sequence of block and ash flow deposits, within which occurs a distinctive vulcanian fall deposit. These are overlain, with no evidence of an intervening paleosol, by a sequence of ignimbrites containing welded horizons (ranging in thickness from around 4 m to 16m). The lack of fall deposits beneath the ignimbrites suggest they may have been formed by instantaneous continuous collapse of the eruption column. This whole succession is overlain by a series of planar and dune bedded pumiceous surge deposits with interbedded pumiceous lapilli fall and ash fall deposits, that extend laterally outside of the main area of ignimbrite deposition. Beds within this upper sequence often contain accretionary lapilli and gas cavities suggesting magma-water interaction. The youngest deposits from Morne Diablotins appear to be valley- fill deposits of both ignimbrite and block and ash flow. A comparison of the of the Grande Savane pyroclastic sequence with the Pointe Ronde (west coast) and Londonderry (east coast) pyroclastic flow fans will provide information on the eruptive history of this major Plinian episode.

  11. Along the Grand Trunk Road: The Photography of Raghubir Singh

    Directory of Open Access Journals (Sweden)

    Chaya Chandrasekhar

    2013-05-01

    Full Text Available For more than two millennia, the historic Grand Trunk Road, the busy thoroughfare that extends some 1500 miles through north India and Pakistan served as the main artery of South Asia. It was also the gateway through which waves of immigrants, travelers, and invaders entered the subcontinent. As a result, a great deal of diversity and tolerance marks the road. Between 1988 and 1991, Raghubir Singh (1942-1999, one of India’s renowned documentary photographers, traveled and photographed the Indian stretch of the Road. Ninety-six photographs from his journeys appear in the publication, 'The Grand Trunk Road: A Passage Through India '(1995. Singh used the pictorial style of street photography that he is known for to capture everyday life along the path. Further, he emphasized the tremendous diversity he witnessed along the road through the selections he made for inclusion in the book and the specific manner in which he arranged many of them. By underscoring the heterogeneity, Singh provided a critical visual commentary of the political climate in India during the 1980s and early nineties. This period coincided with the rise of Hindu nationalism, which aimed to erase the subcontinent’s diverse past and promote instead the idea of a homogenous/Hindu India. By documenting the road in his uniquely pictorial style and arranging the photographs in his book to draw attention to the differences and tolerance witnessed along the path, Singh demonstrated that India was not a monolithic culture as the politics of the time claimed, but a rich interwoven fabric of many varied strands.

  12. Fatores associados ao atraso no desenvolvimento em crianças, Rio Grande, Rio Grande do Sul, Brasil Factores asociados con retraso en el desarrollo de los niños, Rio Grande, Rio Grande do Sul, Brasil Factors associated with delay in development in children, Rio Grande, Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Aline Alves Veleda

    2011-03-01

    Full Text Available Estudo analítico com o objetivo de avaliar os fatores associados ao atraso no desenvolvimento em crianças entre 8 a 12 meses de idade indicadas como de risco ao nascer no município do Rio Grande, Rio Grande do Sul, Brasil. Foram utilizados como instrumentos o Teste de Triagem de Desenvolvimento de Denver II (TTDD II, a avaliação antropométrica e questionários estruturados. Participaram 220 crianças consideradas de risco ou não ao nascer. Foi encontrada uma prevalência de 20,5% de suspeita de atraso no desenvolvimento neuropsicomotor. As crianças que apresentaram risco de um TTDD II suspeito faziam parte de famílias de mais baixa renda; eram filhos de mães que haviam realizado menos de seis consultas de pré-natal e apresentavam índice peso-idade inadequado. Os dados sugerem a necessidade de um replanejamento das políticas de saúde infantil, visto que outros critérios poderiam ser incluídos nas condições de risco para a criança ao nascer.Estudio analítico con el objetivo de evaluar los factores asociados al atraso en el desarrollo en niños de 8 a 12 meses de edad indicados como riesgo al nacer en el municipio de Rio Grande, RS, Brasil. Fueron utilizadas como herramientas la Prueba de Tamizaje del Desarrollo de Denver II, la evaluación antropométrica y cuestionarios estructurados. Participaron 220 niños considerados de riesgo o no al nacer. Fue encontrada una prevalencia del 20,5% de sospecha de atraso en el desarrollo neuropsicomotor. Los niños que presentaron riesgo de un DDST II sospechoso formaban parte de familias de más baja renta; eran hijos de madres que habían realizado menos de seis consultas de prenatal y presentaban índice peso-edad inadecuado. Los datos sugieren la necesidad de un replanteamiento de las políticas de salud infantil, así como otros criterios podrían ser inclusos en las condiciones de riesgo para el niño al nacer.This analytical study aims to evaluate the factors associated to

  13. 78 FR 60994 - Culturally Significant Objects Imported for Exhibition Determinations: “In Grand Style...

    Science.gov (United States)

    2013-10-02

    ... Determinations: ``In Grand Style: Celebrations in Korean Art During the Joseon Dynasty'' SUMMARY: Notice is... objects to be included in the exhibition ``In Grand Style: Celebrations in Korean Art during the Joseon Dynasty,'' imported from abroad for temporary exhibition within the United States, are of cultural...

  14. 75 FR 10308 - Fire Management Plan, Final Environmental Impact Statement, Record of Decision, Grand Canyon...

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF THE INTERIOR National Park Service Fire Management Plan, Final Environmental Impact... Statement for the Fire Management Plan, Grand Canyon National Park. SUMMARY: Pursuant to the National... the Record of Decision for the Fire Management Plan, Grand Canyon National Park, Arizona. On January...

  15. Upper Rio Grande water operations model: A tool for enhanced system management

    Science.gov (United States)

    Gail Stockton; D. Michael Roark

    1999-01-01

    The Upper Rio Grande Water Operations Model (URGWOM) under development through a multi-agency effort has demonstrated capability to represent the physical river/reservoir system, to track and account for Rio Grande flows and imported San Juan flows, and to forecast flows at various points in the system. Testing of the Rio Chama portion of the water operations model was...

  16. Necessity of intermediate mass scales in grand unified theories with spontaneously broken CP invariance

    International Nuclear Information System (INIS)

    Senjanovic, G.

    1982-07-01

    It is demonstrated that the spontaneous breakdown of CP invariance in grand unified theories requires the presence of intermediate mass scales. The simplest realization is provided by weakly broken left-right symmetry in the context of SU(2)sub(L) x SU(2)sub(R) x U(1)sub(B-L) model embedded in grand unified theories. (author)

  17. Exórdio para o estudo da pedagogia libertária em Rio Grande

    OpenAIRE

    Vargas, Francisco Furtado Gomes Riet

    2007-01-01

    Aborda a História da Pedagogia Libertária e suas implicações práticas com ênfase ao Estado do Rio Grande do Sul, no Brasil. It approaches the History of Libertarian Pedagogy and its practical implications with emphasis to the State of Rio Grande do Sul, in Brazil.

  18. Spatial and seasonal variations of the contamination within water body of the Grand Canal, China

    NARCIS (Netherlands)

    Wang, X.L.; Han, Jingyi; Xu, L.G.; Zhang, Q.

    2010-01-01

    To delineate the character of contaminations in the Grand Canal, China, a three-year study (2004-2006) was conducted to investigate variations the water quality in the canal. Results showed that the variation of water quality within the Grand Canal was of there is remarkable spatial and seasonal

  19. 76 FR 6517 - San Luis & Rio Grande Railroad-Petition for a Declaratory Order

    Science.gov (United States)

    2011-02-04

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35380] San Luis & Rio... petition filed by San Luis & Rio Grande Railroad (SLRG), the Board instituted a declaratory order... proposed operation of a truck-to-rail transload facility in Antonito, Colorado. See San Luis & Rio Grande R...

  20. ‘Praise beyond Words’: Psalm 150 as grand finale of the crescendo in the Psalter

    Directory of Open Access Journals (Sweden)

    Dirk J. Human

    2011-04-01

    Full Text Available Without doubt the final hymn of the Psalter can be described as the climax, or grand finale, of the Israelite faith’s most known hymnbook. In this psalm, sound and action are blended into a picture of ecstatic joy. The whole universe is called upon to magnify Yah(weh, the God of Israel. The text poses various exegetical challenges. In the past, Psalm 150 was traditionally analysed as a single text; but with the advent of the canonical and redactionhistorical approaches to the interpretation of the Book of Psalms, Psalm 150 can be interpreted as part of the final Hallel (Pss 146–150, or Book V (Pss 107–150 of the Psalter. This view opens up new possibilities for reading the psalm in broader contexts and its broader literary context(s illuminate its theological significance. This article is an attempt at reflecting on the psalm’s context(s, structure, Gattung and dates of origin, tradition-historical relations to the Pentateuch, Psalms and other Old Testament texts. Ultimately some reflections on the psalm’s theological significance will be suggested.

  1. Municipal solid waste characterizations and management strategies for the Lower Rio Grande Valley, Texas.

    Science.gov (United States)

    Chang, Ni-Bin; Davila, Eric

    2008-01-01

    The Lower Rio Grande Valley (LRGV or Valley) in Texas, facing the big waste management challenge along the US-Mexico border today, is at the crossroads as a result of the rapid population growth, the scarcity of landfill space, the bi-nation's trade impacts, and the illusive goal of environmental sustainability. This paper offers a unique municipal solid waste investigation with regard to both physical and chemical characteristics leading to illuminate the necessary management policies with greater regional relevancy. With multiple sampling campaigns conducted during the spring of 2005, this study holistically summarizes the composition of solid waste, the statistical distribution patterns of key recyclable items, and the heating value in an uncertain environment. Research findings indicate that high fractions of plastics and paper in the waste stream imply a strong potential for energy recovery. Incineration options are thus bolstered by mildly high heating values across 10 cities in this region, which may lead to save land resources required for final disposal and increase electricity generation in the long run. Additional regression analyses further identify the correlation between recyclable items and heating value, which show that current recycling programs permit no obvious negative impacts on the incineration option. Final statistical hypothesis tests for both the Brownsville-Harlingen-San Benito and the McAllen-Edinburg-Mission metropolitan regions help foster consistent management strategies across the Valley regardless of the trivial differences of waste characteristics in between.

  2. Grand Narrative Pemberantasan Korupsi dalam Wacana Konflik Sepak Bola di Media Cetak

    Directory of Open Access Journals (Sweden)

    Afdal Makkuraga Putra

    2017-05-01

    Full Text Available Eradication of corruption has been a grand narrative since the early of reformation era. Mass media became part of the preservation of the grand narrative. Grand narrative is the main narration which becomes basis and universal character since it can be used as standard to measure and assess other narratives. This study analyzes grand narrative of corruption eradication in Indonesia soccer conflict in print media by using critical discourse by Norman Fairclough as research method. The result shows that media preserved grand narrative of corruption eradication through image projection of corruptors as common enemy. The spread of anti-corruption information through mass media carried out continuously and sustainably is a manifestation of the commitment to fight corruption. Information provided by media does not only explains the state’s loss but up to the development of its completion.

  3. O serviço social em indústrias de grande porte do Rio Grande do Sul = Social work in big companies in Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Ziliotto, Denise Macedo

    2010-01-01

    Full Text Available A temática deste artigo centra-se na prática profissional do assistente social na área empresarial, especialmente em indústrias de grande porte. Pretende contribuir na explicitação da especificidade do exercício profissional do Serviço Social nas organizações, entendido como uma atividade inserida na divisão sociotécnica do trabalho e sendo perpassada pelas transformações que estão ocorrendo no mundo laboral nas últimas décadas. A pesquisa foi realizada com profissionais atuantes no contexto investigado através de entrevistas pessoais, avaliadas pela análise de conteúdo. Os resultados obtidos sugerem a atuação predominante de mulheres com formação em universidades privadas, com trajetória profissional majoritária no setor empresarial. Os processos desenvolvidos pelas entrevistadas buscam reverter a imagem assistencialista do campo, valorizando as relações no trabalho e a sinergia com a organização como um todo. A importância do conhecimento multidisciplinar como instrumento para as intervenções e do posicionamento crítico diante das demandas que lhe são dirigidas na dinâmica organizacional foram evidenciados na pesquisa. O caráter recente e ainda restrito da presença dos profissionais no segmento industrial sinaliza um processo de inserção e reconhecimento ainda em construção

  4. Diagnóstico da floricultura no Rio Grande do Sul Diagnosis of floriculture in Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Atelene Normann Kämpf

    1999-09-01

    Full Text Available O objetivo deste trabalho foi avaliar o segmento da produção de flores e plantas ornamentais no Rio Grande do Sul, Brasil, por meio de um levantamento a campo. O estudo faz parte de um projeto global, apoiado pelo Instituto Brasileiro de Floricultura (IBRAFLOR e pelo Ministério da Agricultura e do Abastecimento (MAARA, através do Departamento Nacional de Cooperativismo (DENACOOP. Com base nos formulários preenchidos nas propriedades, foi elaborado um cadastro dos floricultores, com seus endereços e produções. A floricultura gaúcha conta com 257 produtores, que cultivam o total de 304ha em 65 municípios; 30% dessa área é ocupada com flores de corte, 33% com mudas para jardim, 29% com outros produtos da floricultura e 8% com plantas envasadas. O sistema de cultivo predominante é a céu aberto (89%, com baixos investimentos tecnológicos.A survey was conducted to quantify flower and ornamental plant production in the State of Rio Grande do Sul State, Brazil. The Brazilian Floriculture Institute (IBRAFLOR and the Agriculture Ministry (MAARA - DENACOOP granted this research. Based on an inventory formulary a catalog including the nurseries, addresses and main crops was elaborated. There are 257 growers in this State with an area of 304ha distributed among 65 counties; 30% of this area are cultivated with cut flowers, 33% with annuals and perennials for garden, 29% with other floriculture products and 8% with potted plants. The main system of cultivation is not protected with low technological investments.

  5. DARPA Technical Accomplishments. An Historical Review of Selected DARPA Projects. Volume 1

    Science.gov (United States)

    1990-02-01

    According to Mr. Albert Rubenstein, ARPA program manager at the time, Bell Telephone Laboratories (BTL), then constructing the Army’s Nike-Zeus Ballistic...18th Tri- Service Radar Symposiun, 1972, Vol. 1, p. 21. 14 Discussion with Mr. Albert Rubenstein, IDA, ARPA Defender Program Manager in 1958-59...in its use in Vietnam. 16-3 X26B-QT-2 INDUSTRY SAILPLANE TECHNOLOGY NAVY TEST PILOT TRNG ARMY SCHWEITZER AGILE VN REQUIREMENT I mmi" -" ~ ~ M . . •1OD

  6. DARPA Technical Accomplishments. Volume 2. An Historical Review of Selected DARPA Projects

    Science.gov (United States)

    1991-04-01

    without regard to biological realism ). 6 Image understanding is very different from image processing, which studies image- to-in’age transformation, not...to note that Jacobs and Weltnma.’ brought, respectively, radar and cinematic technology orientations to the work through theit family experiences and...eed for realistic battle-engagement simulation as followE: The next issue is thati-.f putting, as well as one can, wartime realism into simulation

  7. Middle Rio Grande Water Sustainability in Extreme Drought: Using Provenance to Trace Modeling Scenarios Selected by Users

    Science.gov (United States)

    Pennington, D. D.; Garnica Chavira, L.; Villanueva-Rosales, N.

    2017-12-01

    People living in the vicinity of the middle Rio Grande from Elephant Butte Reservoir in New Mexico through Fort Quitman, Texas, including inhabitants on the Mexican side of the river, are confronted with numerous challenges that include drought, population growth, reduced surface water quality and quantity, declining aquifers, and expected future increases in temperature with more variable precipitation. The transboundary surface water is subject to complex regulation across two U.S. states and two nations (U.S. and Mexico). This presentation will summarize the modeling efforts of a USDA-funded project to characterize potential future solutions for water sustainability while managing agriculture, economic, and human impacts. It will present an online software system designed for rapid, flexible modeling of different climate, policy, and technology scenarios with stakeholders, and the underlying intelligent system that manages model selection, data and parameters, and user choices, and provides a provenance trace based on the W3C PROV standard.

  8. Harnessing the hydropower potential in Africa: What should be the place and role of Grand Inga hydropower project?

    Energy Technology Data Exchange (ETDEWEB)

    Fall, Latsoucabe

    2010-09-15

    Harnessing Africa's huge hydropower potential should be made a priority for the sustainable development of the Continent. Particularly, Grand Inga hydropower project in DRC, due to its gigantic size (40,000 MW) and favourable natural characteristics, could be 'Africa's flagship Project of the 21st Century' offering enormous comparative advantages and opportunities for the benefits of the entire African Continent. Nevertheless, to make it a feasible and palpable 'Model Project', capable of producing clean and affordable energy, the paper tries to respond to key questions on the several daunting challenges to address for its sustainable, cost-effective and timely development and operation.

  9. Submarine landslides: advances and challenges

    Science.gov (United States)

    Locat, Jacques; Lee, Homa J.

    2002-01-01

    Due to the recent development of well-integrated surveying techniques of the sea floor, significant improvements were achieved in mapping and describing the morphology and architecture of submarine mass movements. Except for the occurrence of turbidity currents, the aquatic environment (marine and fresh water) experiences the same type of mass failure as that found on land. Submarine mass movements, however, can have run-out distances in excess of 100 km, so their impact on any offshore activity needs to be integrated over a wide area. This great mobility of submarinemass movements is still not very well understood, particularly for cases like the far-reaching debris flows mapped on the Mississippi Fan and the large submarine rock avalanches found around many volcanic islands. A major challenge ahead is the integration of mass movement mechanics in an appropriate evaluation of the hazard so that proper risk assessment methodologies can be developed and implemented for various human activities offshore, including the development of natural resources and the establishment of reliable communication corridors. Key words : submarine slides, hazards, risk assessment, morphology, mobility, tsunami. Le dveloppement rcent de techniques de levs hydrograhiques pour les fonds marins nous a permis d'atteindre une qualit ingale dans la cartographie et la description des glissements sous marins. l'exception des courants de turbidit, on retrouve dans le domaine aquatique les mmes types de mouvements de terrain que sur terre. Par contre, les glissements sous-marins peuvent atteindre des distances excdant 100 km de telle sorte que leur impact sur les activits offshore doit tre pris en compte sur degrandes tendues. La grande mobilit des glissements sous-marins n'est pas encore bien comprise, comme pour le cas des coules dedbris cartographies sur le cne du Mississippi ainsi que pour les grandes avalanches rocheuses sous-marines retrouves au pourtour des les volcaniques. Un dfi majeur

  10. Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank

    Science.gov (United States)

    Ramirez-Zamora, Adolfo; Giordano, James J.; Gunduz, Aysegul; Brown, Peter; Sanchez, Justin C.; Foote, Kelly D.; Almeida, Leonardo; Starr, Philip A.; Bronte-Stewart, Helen M.; Hu, Wei; McIntyre, Cameron; Goodman, Wayne; Kumsa, Doe; Grill, Warren M.; Walker, Harrison C.; Johnson, Matthew D.; Vitek, Jerrold L.; Greene, David; Rizzuto, Daniel S.; Song, Dong; Berger, Theodore W.; Hampson, Robert E.; Deadwyler, Sam A.; Hochberg, Leigh R.; Schiff, Nicholas D.; Stypulkowski, Paul; Worrell, Greg; Tiruvadi, Vineet; Mayberg, Helen S.; Jimenez-Shahed, Joohi; Nanda, Pranav; Sheth, Sameer A.; Gross, Robert E.; Lempka, Scott F.; Li, Luming; Deeb, Wissam; Okun, Michael S.

    2018-01-01

    The annual Deep Brain Stimulation (DBS) Think Tank provides a focal opportunity for a multidisciplinary ensemble of experts in the field of neuromodulation to discuss advancements and forthcoming opportunities and challenges in the field. The proceedings of the fifth Think Tank summarize progress in neuromodulation neurotechnology and techniques for the treatment of a range of neuropsychiatric conditions including Parkinson's disease, dystonia, essential tremor, Tourette syndrome, obsessive compulsive disorder, epilepsy and cognitive, and motor disorders. Each section of this overview of the meeting provides insight to the critical elements of discussion, current challenges, and identified future directions of scientific and technological development and application. The report addresses key issues in developing, and emphasizes major innovations that have occurred during the past year. Specifically, this year's meeting focused on technical developments in DBS, design considerations for DBS electrodes, improved sensors, neuronal signal processing, advancements in development and uses of responsive DBS (closed-loop systems), updates on National Institutes of Health and DARPA DBS programs of the BRAIN initiative, and neuroethical and policy issues arising in and from DBS research and applications in practice. PMID:29416498

  11. Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank

    Directory of Open Access Journals (Sweden)

    Adolfo Ramirez-Zamora

    2018-01-01

    Full Text Available The annual Deep Brain Stimulation (DBS Think Tank provides a focal opportunity for a multidisciplinary ensemble of experts in the field of neuromodulation to discuss advancements and forthcoming opportunities and challenges in the field. The proceedings of the fifth Think Tank summarize progress in neuromodulation neurotechnology and techniques for the treatment of a range of neuropsychiatric conditions including Parkinson's disease, dystonia, essential tremor, Tourette syndrome, obsessive compulsive disorder, epilepsy and cognitive, and motor disorders. Each section of this overview of the meeting provides insight to the critical elements of discussion, current challenges, and identified future directions of scientific and technological development and application. The report addresses key issues in developing, and emphasizes major innovations that have occurred during the past year. Specifically, this year's meeting focused on technical developments in DBS, design considerations for DBS electrodes, improved sensors, neuronal signal processing, advancements in development and uses of responsive DBS (closed-loop systems, updates on National Institutes of Health and DARPA DBS programs of the BRAIN initiative, and neuroethical and policy issues arising in and from DBS research and applications in practice.

  12. Particle physics models of inflation in supergravity and grand unification

    International Nuclear Information System (INIS)

    Kostka, Philipp Manuel

    2010-01-01

    In the first part of this thesis, we study classes of hybrid and chaotic inflation models in four-dimensional N=1 supergravity. Therein, the η-problem can be resolved relying on fundamental symmetries in the Kaehler potential. Concretely, we investigate explicit realizations of superpotentials, in which the flatness of the inflaton potential is protected at tree level by a shift symmetry or a Heisenberg symmetry in the Kaehler potential. In the latter case, the associated modulus field can be stabilized during inflation by supergravity effects. In the context of hybrid inflation, a novel class of models, to which we refer as ''tribrid inflation,'' turns out to be particularly compatible with such symmetry solutions to the η-problem. Radiative corrections due to operators in the superpotential, which break the respective symmetry, generate the required small slope of the inflaton potential. Additional effective operators in the Kaehler potential can reduce the predicted spectral index so that it agrees with latest observational data. Within a model of chaotic inflation in supergravity with a quadratic potential, we apply the Heisenberg symmetry to allow for viable inflation with super-Planckian field values, while the associated modulus is stabilized. We show that radiative corrections are negligible in this context. In the second part, the tribrid inflation models are extended to realize gauge non-singlet inflation. This is applied to the matter sector of supersymmetric Grand Unified Theories based on the Pati-Salam gauge group. For the specific scenario in which the right-handed sneutrino is the inflaton, we study the scalar potential in a D-flat valley. We show that despite potentially dangerous two-loop corrections, the required flatness of the potential can be maintained. The reason for this is the strong suppression of gauge interactions of the inflaton field due to its symmetry breaking vacuum expectation value. In addition, the production of stable

  13. Did a slump source cause the 1929 Grand Banks tsunami?

    Science.gov (United States)

    Løvholt, F.; Schulten, I.; Mosher, D.; Harbitz, C. B.; Krastel, S.

    2017-12-01

    On November 18, 1929, a Mw 7.2 earthquake occurred beneath the upper Laurentian Fan, south of Newfoundland. The earthquake displaced about 100 km3 of sediment volume that rapidly evolved into a turbidity current revealed by a series of successive telecommunication cable breaks. A tsunami with fatal consequences along the south coast of Newfoundland also resulted. This tsunami is attributed to sediment mass failure as no seafloor displacement due to the earthquake is observed or expected. Although sidescan sonar, sub-bottom profiler and modern multibeam data show surficial sediment slumping and translational slide activity in the upper part of the slope, no major headscarp, single evacuation area or large mass transport deposit are observed. Sediment mass failure has been interpreted as broadly distributed and shallow, likely occurring in a retrogressive fashion. The question remained, therefore, as to how such complex failure kinematics could generate a tsunami. The Grand Banks tsunami is the only landslide tsunami for which traces are found at transoceanic distances. Despite being a landmark event, only a couple of attempts to model the tsunami exist. None of these have been able to match tsunami observations. Recently acquired seismic reflection data suggest that rotational slumping of a thick sediment mass ( 500 m) on the St. Pierre Slope may have occurred, causing seafloor displacements (fault traces) up to 100 m in height. The previously mapped surficial failures were a consequence of slumping of the thicker mass. Here, we simulate tsunami generation using the new geophysical information to construct different tsunamigenic slump sources. In addition, we undertake simulations assuming a flowing surficial landslide. The numerical simulations shows that its large and rapid vertical displacements render the slump source more tsunamigenic than the alternative surficial landslide. The simulations using the slump source roughly complies with observations of large run

  14. Particle physics models of inflation in supergravity and grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Kostka, Philipp Manuel

    2010-12-03

    In the first part of this thesis, we study classes of hybrid and chaotic inflation models in four-dimensional N=1 supergravity. Therein, the {eta}-problem can be resolved relying on fundamental symmetries in the Kaehler potential. Concretely, we investigate explicit realizations of superpotentials, in which the flatness of the inflaton potential is protected at tree level by a shift symmetry or a Heisenberg symmetry in the Kaehler potential. In the latter case, the associated modulus field can be stabilized during inflation by supergravity effects. In the context of hybrid inflation, a novel class of models, to which we refer as ''tribrid inflation,'' turns out to be particularly compatible with such symmetry solutions to the {eta}-problem. Radiative corrections due to operators in the superpotential, which break the respective symmetry, generate the required small slope of the inflaton potential. Additional effective operators in the Kaehler potential can reduce the predicted spectral index so that it agrees with latest observational data. Within a model of chaotic inflation in supergravity with a quadratic potential, we apply the Heisenberg symmetry to allow for viable inflation with super-Planckian field values, while the associated modulus is stabilized. We show that radiative corrections are negligible in this context. In the second part, the tribrid inflation models are extended to realize gauge non-singlet inflation. This is applied to the matter sector of supersymmetric Grand Unified Theories based on the Pati-Salam gauge group. For the specific scenario in which the right-handed sneutrino is the inflaton, we study the scalar potential in a D-flat valley. We show that despite potentially dangerous two-loop corrections, the required flatness of the potential can be maintained. The reason for this is the strong suppression of gauge interactions of the inflaton field due to its symmetry breaking vacuum expectation value. In addition, the

  15. REESTRUTURAÇÃO PRODUTIVA NO RIO GRANDE DO NORTE

    Directory of Open Access Journals (Sweden)

    Francisco Fransualdo de Azevedo

    2013-01-01

    Full Text Available El objetivo de este articulo es analizar el proceso de reestruturación produtiva del sistema capitalista, discu- tiendo sus distintas dimensiones, concretamente la económica, social, política y técnica. Se trata, por tanto, de explicar como este proceso se à desarrollando em el territorio de Rio Grande do Norte (Brasil, teniendo em cuenta las vuejas y nuevas materialidades que constituyen este proceso de producción del espacio durante las últimas décadas. Al mismo tiempo que lo ayudan a explicar. Desde el punto de vista metodológico, se hace una breve revisión teórica y conceptual acerca de la recolección de datos y la sistematización y ana- lisi de los datos procedentes de fuentes oficiales. Como son las secretarias y los organos gubernamentales -Instituto Brasileiro de Geografia e Estatística, Instituto de Desenvolvimento Sustentável e Meio Ambiente do Rio Grande do Norte, Agência Nacional de Petróleo, Serviço Brasileiro de Apoio às Micro e Pequenas Empresas- y también algunas instituciones académicas, como es el caso del Observatório das Metrópoles. De todo ello parece desprenderse que los años 1980/90 estuvieron marcados por cambios importantes em el proceso de producción del espacio potiguar, destacando em particular los que estuvieron asociados a los incentivos estatales, em consonancia con acciones e intenciones del capítal privado interessado em el fo- mento de la reeestructuración de las actividades em todo el arco de la estructura económica: las actividades agropeciarias, la pesca, y la carcinicultura, así como el turismo, la extracción minera, la construcción de infrestructuras públicas, la industria textil, el comercio y los servicios.

  16. Descriptive summary of the Grande Ronde Basalt type section, Columbia River Basalt Group

    International Nuclear Information System (INIS)

    Camp, V.E.; Price, S.M.; Reidel, S.P.

    1978-10-01

    The Grande Ronde Basalt type section, located in extreme southeastern Washington, was measured, sampled, and characterized. The section is 800 meters thick and is comprised of 35 Grande Ronde Basalt flows. These flows are divisible into 3 magnetostratiographic units termed, in ascending order, the R 1 , the N 1 , and the R 2 . The R 1 unit is represented by 13 reversely polarized flows; the N 1 unit, by 13 normally polarized flows; and the R 2 , by 9 reversely polarized flows. Chemically, the Grande Ronde Basalt flows are divided into 2 major groups, termed A and B. The compositions of the lower 9 flows, members of Group A, are similar to either the high-Mg Grande Ronde chemical type, the high-Ti Grande Ronde chemical type, or the Pomona chemical type. The compositions of the upper 25 flows, members of Group B, are predominantly similar to the low-Mg Grande Ronde chemical type. Petrographically, the Grande Ronde Basalt flows are generally fine grained and aphyric, and have a intergranular or intersertal micro-texture. Major mineral phases include plagioclase (An/sub 40-60/) and augite; minor mineral phases include pigeonite, orthopyroxene, ilmenite, titanomagnetite, and olivine. Group A flows generally contain more olivine and less pigeonite than do Group B flows. 6 figures, 6 tables

  17. Populating a Control Point Database: A cooperative effort between the USGS, Grand Canyon Monitoring and Research Center and the Grand Canyon Youth Organization

    Science.gov (United States)

    Brown, K. M.; Fritzinger, C.; Wharton, E.

    2004-12-01

    The Grand Canyon Monitoring and Research Center measures the effects of Glen Canyon Dam operations on the resources along the Colorado River from Glen Canyon Dam to Lake Mead in support of the Grand Canyon Adaptive Management Program. Control points are integral for geo-referencing the myriad of data collected in the Grand Canyon including aerial photography, topographic and bathymetric data used for classification and change-detection analysis of physical, biologic and cultural resources. The survey department has compiled a list of 870 control points installed by various organizations needing to establish a consistent reference for data collected at field sites along the 240 mile stretch of Colorado River in the Grand Canyon. This list is the foundation for the Control Point Database established primarily for researchers, to locate control points and independently geo-reference collected field data. The database has the potential to be a valuable mapping tool for assisting researchers to easily locate a control point and reduce the occurrance of unknowingly installing new control points within close proximity of an existing control point. The database is missing photographs and accurate site description information. Current site descriptions do not accurately define the location of the point but refer to the project that used the point, or some other interesting fact associated with the point. The Grand Canyon Monitoring and Research Center (GCMRC) resolved this problem by turning the data collection effort into an educational exercise for the participants of the Grand Canyon Youth organization. Grand Canyon Youth is a non-profit organization providing experiential education for middle and high school aged youth. GCMRC and the Grand Canyon Youth formed a partnership where GCMRC provided the logistical support, equipment, and training to conduct the field work, and the Grand Canyon Youth provided the time and personnel to complete the field work. Two data

  18. Histoplasmose pulmonar aguda no Rio Grande do Sul Acute pulmonary histoplasmosis in the State of Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Gisela Unis

    2005-02-01

    Full Text Available INTRODUÇÃO: A histoplasmose pulmonar aguda depende da inalação de uma grande quantidade de propágulos fúngicos por um paciente hígido. O tempo de exposição determina a gravidade da doença. Uma epidemia é influenciada por fatores que afetam o crescimento e a transmissão do Histoplasma capsulatum var. capsulatum na natureza. OBJETIVO: Identificar os aspectos epidemiológicos e clínico-laboratoriais dos pacientes com histoplasmose pulmonar aguda no Rio Grande do Sul e compará-los com as microepidemias relatadas no Brasil. MÉTODO: Foram revisados 212 prontuários clínicos de pacientes com histoplasmose dos arquivos do Laboratório de Micologia do Complexo Hospitalar Santa Casa de Porto Alegre (RS num período de 25 anos (1977-2002. Foram identificados e incluídos no estudo os casos de histoplasmose pulmonar aguda com cultivo positivo e/ou achado histopatológico compatível. As microepidemias foram diagnosticadas com a comprovação de um caso ou evidência soromicológica com história clínica compatível. Foram revisadas as microepidemias publicadas no Brasil. RESULTADOS: Dezoito de um total de 212 pacientes (8,5% foram incluídos no trabalho. A idade variou de 8 a 63 anos (média de 35,4; mediana de 34,5, e 67% eram do sexo masculino. A história epidemiológica foi sugestiva em 11 pacientes (61%. O tipo primário de histoplasmose pulmonar aguda foi o mais freqüente (17; 95%. Houve predomínio de casos isolados. CONCLUSÃO: O reconhecimento de casos isolados e a presença de microepidemias demonstram a abundância do H. capsulatum no solo, e juntamente com a ocorrência de todas as formas da doença, confirmam o Rio Grande do Sul como hiperendêmico para histoplasmose.BACKGROUND: Acute pulmonary histoplasmosis is a respiratory infection occurring when an otherwise healthy individual inhales a large quantity of fungal propagules. Length of exposure determines disease severity. An epidemic is influenced by factors affecting the

  19. A Nurse-Led Innovation in Education: Implementing a Collaborative Multidisciplinary Grand Rounds.

    Science.gov (United States)

    Matamoros, Lisa; Cook, Michelle

    2017-08-01

    Multidisciplinary grand rounds provides an opportunity to promote excellence in patient care through scholarly presentations and interdisciplinary collaboration with an innovative approach. In addition, multidisciplinary grand rounds serves to recognize expertise of staff, mentor and support professional development, and provide a collaborative environment across all clinical disciplines and support services. This article describes a process model developed by nurse educators for implementing a multidisciplinary grand rounds program. The components of the process model include topic submissions, coaching presenters, presentations, evaluations, and spreading the work. This model can be easily implemented at any organization. J Contin Educ Nurs. 2017;48(8):353-357. Copyright 2017, SLACK Incorporated.

  20. Terracina - terra di briganti, tappa prediletta dai (grand- turisti

    Directory of Open Access Journals (Sweden)

    Clemens Arts

    2012-05-01

    Full Text Available Terracina: bandit territory and resort cherished by (grand- touristsFor travellers who left the Eternal City, Terracina was one of the first stages, and almost an obligatory one, on their way to Naples and further south. The charming fishing town on the Tyrrhenian Sea situated on the Via Appia offered to those who had crossed the boring and bothersome Pontine Marshes a glimpse of the lushest Mediterranean vegetation and views. Yet another aspect of Terracina’s historical background is the protracted terrifying presence of notorious bandits such as Fra Diavolo and Gasbarrone.This article questions the imagological implications of these mytho-cultural assets of Terracina in literature, with a focus on ‘Romantic’ early Nineteen Century travel literature at large (Irving Washington, Stendhal, in which the point of view is mostly from a visitor's perspective, whereas authoritative studies, e.g. by Eric Hobsbawm, have rightly stressed the crucial importance of the insiders’ point of view as well.As an excursus from this cultural and historical context Pier Paolo Pasolini’s delicious ‘Terracina’ comes in to offer just such an insider’s point of view, telling the story of two Roman ‘ragazzi di vita’ – or ‘briganti’, as the villagers call them – who become tourists themselves and get fatally attracted by the idyllic Terracina seascape.