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Sample records for cyclic behavior due

  1. Breaking antidunes: Cyclic behavior due to hysteresis

    DEFF Research Database (Denmark)

    Deigaard, Rolf

    2006-01-01

    The cyclic behavior of breaking antidunes (growth, breaking of surface wave, obliteration) is investigated by use of a numerical model. The model includes the transition between supercritical and transcritical flow. As the antidune grows the flow becomes transcritical and a hydraulic jump is form...... upstream of the antidune crest. The relation between growth of the antidune and supercritical flow and between decay and transcritical flow is shown, and the significance of hysteresis in the flow conditions is investigated....

  2. Cyclic Shearing Deformation Behavior of Saturated Clays

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The apparatus for static and dynamic universal triaxial and torsional shear soil testing is employed to perform stress-controlled cyclic single-direction torsional shear tests and two-direction coupled shear tests under unconsolidated-undrained conditions. Through a series of tests on saturated clay, the effects of initial shear stress and stress reversal on the clay's strain-stress behavior are examined, and the behavior of pore water pressure is studied. The experimental results indicate that the patterns of stress-strain relations are distinctly influenced by the initial shear stress in the cyclic single-direction shear tests. When the initial shear stress is large and no stress reversal occurs, the predominant deformation behavior is characterized by an accumulative effect. When the initial shear stress is zero and symmetrical cyclic stress occurs, the predominant deformation behavior is characterized by a cyclic effect. The pore water pressure fluctuates around the confining pressure with the increase of cycle number. It seems that the fluctuating amplitude increases with the increase of the cyclic stress. But a buildup of pore water pressure does not occur. The deformations of clay samples under the complex initial and the cyclic coupled stress conditions include the normal deviatoric deformation and horizontal shear deformation, the average deformation and cyclic deformation. A general strain failure criterion taking into account these deformations is recommended and is proved more stable and suitable compared to the strain failure criteria currently used.

  3. Cyclic behaviors of amorphous shape memory polymers.

    Science.gov (United States)

    Yu, Kai; Li, Hao; McClung, Amber J W; Tandon, Gyaneshwar P; Baur, Jeffery W; Qi, H Jerry

    2016-04-01

    Cyclic loading conditions are commonly encountered in the applications of shape memory polymers (SMPs), where the cyclic characteristics of the materials determine their performance during the service life, such as deformation resistance, shape recovery speed and shape recovery ratio. Recent studies indicate that in addition to the physical damage or some other irreversible softening effects, the viscoelastic nature could also be another possible reason for the degraded cyclic behavior of SMPs. In this paper, we explore in detail the influence of the viscoelastic properties on the cyclic tension and shape memory (SM) behavior of an epoxy based amorphous thermosetting polymer. Cyclic experiments were conducted first, which show that although the epoxy material does not have any visible damage or irreversible softening effect during deformation, it still exhibits obvious degradation in the cyclic tension and SM behaviors. A linear multi-branched model is utilized to assist in the prediction and understanding of the mechanical responses of amorphous SMPs. Parametric studies based on the applied model suggest that the shape memory performance can be improved by adjusting programming and recovery conditions, such as lowering the loading rate, increasing the programming temperature, and reducing the holding time.

  4. Cyclical Cushing's syndrome due to an atypical thymic carcinoid

    NARCIS (Netherlands)

    Meinardi, [No Value; van den Berg, G; Wolffenbuttel, BHR; Kema, IP; Dullaart, RPF

    A 43-year-old man presented with fluctuating symptoms of weight gain, shortness of breath, pretibial oedema, associated with anxiety and memory disturbances. Laboratory investigation revealed an adrenocorticotropin (ACTH)-dependent cyclical Cushing's syndrome characterised by remarkable variations

  5. Paediatric cyclical Cushing's disease due to corticotroph cell hyperplasia.

    LENUS (Irish Health Repository)

    Noctor, E

    2015-06-01

    Cushing\\'s disease is very rare in the paediatric population. Although uncommon, corticotroph hyperplasia causing Cushing\\'s syndrome has been described in the adult population, but appears to be extremely rare in children. Likewise, cyclical cortisol hypersecretion, while accounting for 15 % of adult cases of Cushing\\'s disease, has only rarely been described in the paediatric population. Here, we describe a very rare case of a 13-year old boy with cyclical cortisol hypersecretion secondary to corticotroph cell hyperplasia.

  6. Experimental Research on the Dynamic Compressive Behaviors of CA Mortar Due to Cyclic Loading History%循环荷载历史下 CA 砂浆的动态受压试验研究

    Institute of Scientific and Technical Information of China (English)

    王平; 王彪; 徐浩

    2015-01-01

    研究目的:为研究历经不同循环荷载历史和不同应变速率对铁路轨道系统 CRTSⅠ型板式无砟轨道水泥乳化沥青砂浆(CA 砂浆)的抗压强度、弹性模量和峰值应变的影响规律,进行 CA 砂浆圆柱体试件历经循环加载历史后,在应变速率为1×10-5~1×10-2 s -1时的单轴受压特性试验。  研究结论:(1)应变速率和循环荷载历史对 CA 砂浆的力学性能影响显著;(2)CA 砂浆的抗压强度、弹性模量和峰值应变均随应变速率的增大而提高;(3)在相同的应变速率下,CA 砂浆的抗压强度随循环荷载次数和循环荷载幅值的增加而降低,最大降低幅度为8.34%;(4)当循环荷载幅值较小时,CA 砂浆的弹性模量随循环荷载次数的增加而增大,最大增加幅度为59.17%;(5)在相同的应变速率下,CA 砂浆的峰值应变随循环荷载次数及循环荷载幅值的增大呈降低趋势,且应变速率对峰值应变的影响小于循环荷载历史的影响;(6)该研究成果为进一步了解历经循环加载历史后板式无砟轨道的力学性能提供必要的试验依据,进而应用于指导 CA 砂浆材料优化设计中。%Research purposes:In order to analyze the influence on the change rule of compressive strength,elastic modulus and peak strain of China railway track system(CRTS)Ⅰslab track cement asphalt mortar(CA mortar)by different cyclic loading histories and strain rates.The uniaxial compression characteristic test of CA mortar cylinder specimens due to cyclic loading histories with the strain rates ranging from 1 ×10 -5 s -1 to 1 ×10 -2 s -1 was carried out. Research conclusions:(1)The mechanical property of CA mortar is affected obviously by strain rates and cyclic loading histories.(2)The compressive strength,elastic modulus and peak strain of CA mortar are increase with the strain rate. (3)The compressive strength of CA mortar

  7. Undrained dynamical behavior of Nanjing flake-shaped fine sand under cyclic loading

    Institute of Scientific and Technical Information of China (English)

    陈国兴; 刘雪珠; 战吉艳

    2008-01-01

    A series of dynamic behavior tests on Nanjing flake-shaped fine sand were performed by using the WFI cyclic triaxial apparatus made in England. The dynamic behaviors of Nanjing flake-shaped fine sand under different static deviator stress levels and cyclic stress ratios were studied. Through comparing the effective stress path under cyclic loading with static loading, the processes of liquefaction of saturated Nanjing flake-shaped fine sand with development of dynamic pore-water pressure, including the initial compact state, compression state and dilative state, were investigated. The variation of the shear stiffness with the number of cycles and cyclic strain was investigated by analyzing the secant shear modulus in each unload-reload loop of dynamic stress-strain relationship. And by means of the exponential function, the empirical equations of the relationship between secant shear modulus Gsec, shear modulus ratio Gsec/Gmax and cyclic strain ε were established based on series of test results. The results show that according to different combinations of static deviator stress and cyclic stress, two kinds of failure patterns with deviator stress reversal or no deviator stress reversal are observed in the samples tested in this series, including cyclic mobility and the failure of accumulation residual strain. In addition, the degradation of dynamic shear modulus is due to the development of vibration pore-water pressure and it is observed that the shear modulus reduces with the progressive number of cycles.

  8. Macro-residual strains due to cyclic loading of composites

    CERN Document Server

    Hashin, Z

    1999-01-01

    Macro-residual strains produced by load cycles on elastic-brittle composites are analytically expressed in terms of the effective thermal expansion coefficients of the composite as affected by the damage states developing during the $9 cycling. Limiting values of residual strain are evaluated for unidirectional fiber composites and cross-ply laminates. Frictional losses due to internal sliding are not considered. (17 refs).

  9. Behavior of nonplastic silty soils under cyclic loading.

    Science.gov (United States)

    Ural, Nazile; Gunduz, Zeki

    2014-01-01

    The engineering behavior of nonplastic silts is more difficult to characterize than is the behavior of clay or sand. Especially, behavior of silty soils is important in view of the seismicity of several regions of alluvial deposits in the world, such as the United States, China, and Turkey. In several hazards substantial ground deformation, reduced bearing capacity, and liquefaction of silty soils have been attributed to excess pore pressure generation during dynamic loading. In this paper, an experimental study of the pore water pressure generation of silty soils was conducted by cyclic triaxial tests on samples of reconstituted soils by the slurry deposition method. In all tests silty samples which have different clay percentages were studied under different cyclic stress ratios. The results have showed that in soils having clay content equal to and less than 10%, the excess pore pressure ratio buildup was quicker with an increase in different cyclic stress ratios. When fine and clay content increases, excess pore water pressure decreases constant cyclic stress ratio in nonplastic silty soils. In addition, the applicability of the used criteria for the assessment of liquefaction susceptibility of fine grained soils is examined using laboratory test results.

  10. Behavior of Nonplastic Silty Soils under Cyclic Loading

    Directory of Open Access Journals (Sweden)

    Nazile Ural

    2014-01-01

    Full Text Available The engineering behavior of nonplastic silts is more difficult to characterize than is the behavior of clay or sand. Especially, behavior of silty soils is important in view of the seismicity of several regions of alluvial deposits in the world, such as the United States, China, and Turkey. In several hazards substantial ground deformation, reduced bearing capacity, and liquefaction of silty soils have been attributed to excess pore pressure generation during dynamic loading. In this paper, an experimental study of the pore water pressure generation of silty soils was conducted by cyclic triaxial tests on samples of reconstituted soils by the slurry deposition method. In all tests silty samples which have different clay percentages were studied under different cyclic stress ratios. The results have showed that in soils having clay content equal to and less than 10%, the excess pore pressure ratio buildup was quicker with an increase in different cyclic stress ratios. When fine and clay content increases, excess pore water pressure decreases constant cyclic stress ratio in nonplastic silty soils. In addition, the applicability of the used criteria for the assessment of liquefaction susceptibility of fine grained soils is examined using laboratory test results.

  11. Differential self-assembly behaviors of cyclic and linear peptides.

    Science.gov (United States)

    Choi, Sung-ju; Jeong, Woo-jin; Kang, Seong-Kyun; Lee, Myongsoo; Kim, Eunhye; Ryu, Du Yeol; Lim, Yong-beom

    2012-07-01

    Here we ask the fundamental questions about the effect of peptide topology on self-assembly. The study revealed that the self-assembling behaviors of cyclic and linear peptides are significantly different in several respects, in addition to sharing several similarities. Their clear differences included the morphological dissimilarities of the self-assembled nanostructures and their thermal stability. The similarities include their analogous critical aggregation concentration values and cytotoxicity profiles, which are in fact closely related. We believe that understanding topology-dependent self-assembly behavior of peptides is important for developing tailor-made self-assembled peptide nanostructures.

  12. Cyclic Deformation of Advanced High-Strength Steels: Mechanical Behavior and Microstructural Analysis

    Science.gov (United States)

    Hilditch, Timothy B.; Timokhina, Ilana B.; Robertson, Leigh T.; Pereloma, Elena V.; Hodgson, Peter D.

    2009-02-01

    The fatigue properties of multiphase steels are an important consideration in the automotive industry. The different microstructural phases present in these steels can influence the strain life and cyclic stabilized strength of the material due to the way in which these phases accommodate the applied cyclic strain. Fully reversed strain-controlled low-cycle fatigue tests have been used to determine the mechanical fatigue performance of a dual-phase (DP) 590 and transformation-induced plasticity (TRIP) 780 steel, with transmission electron microscopy (TEM) used to examine the deformed microstructures. It is shown that the higher strain life and cyclic stabilized strength of the TRIP steel can be attributed to an increased yield strength. Despite the presence of significant levels of retained austenite in the TRIP steel, both steels exhibited similar cyclic softening behavior at a range of strain amplitudes due to comparable ferrite volume fractions and yielding characteristics. Both steels formed low-energy dislocation structures in the ferrite during cyclic straining.

  13. Deformation Behavior of Recycled Concrete Aggregate during Cyclic and Dynamic Loading Laboratory Tests

    Directory of Open Access Journals (Sweden)

    Wojciech Sas

    2016-09-01

    Full Text Available Recycled concrete aggregate (RCA is a relatively new construction material, whose applications can replace natural aggregates. To do so, extensive studies on its mechanical behavior and deformation characteristics are still necessary. RCA is currently used as a subbase material in the construction of roads, which are subject to high settlements due to traffic loading. The deformation characteristics of RCA must, therefore, be established to find the possible fatigue and damage behavior for this new material. In this article, a series of triaxial cyclic loading and resonant column tests is used to characterize fatigue in RCA as a function of applied deviator stress after long-term cyclic loading. A description of the shakedown phenomenon occurring in the RCA and calculations of its resilient modulus (Mr as a function of fatigue are also presented. Test result analysis with the stress-life method on the Wohler S-N diagram shows the RCA behavior in accordance with the Basquin law.

  14. Cyberbullying behavior and adolescents' use of media with antisocial content: a cyclic process model.

    Science.gov (United States)

    den Hamer, Anouk; Konijn, Elly A; Keijer, Micha G

    2014-02-01

    The present study examined the role of media use in adolescents' cyberbullying behavior. Following previous research, we propose a Cyclic Process Model of face-to-face victimization and cyberbullying through two mediating processes of anger/frustration and antisocial media content. This model was tested utilizing a cross-sectional design with adolescent participants (N=892). Exposure to antisocial media content was measured with a newly developed content-based scale (i.e., the C-ME), showing good psychometric qualities. Results of structural equation modeling showed that adolescents' exposure to antisocial media content was significantly associated with cyberbullying behavior, especially in adolescents who experienced anger and frustration due to face-to-face victimization. Goodness of fit indices demonstrated a good fit of the theoretical model to the data and indicated that exposure to antisocial media content acts as an amplifier in a cyclic process of victimization-related anger and cyberbullying behavior.

  15. On intrinsic time measure in the modeling of cyclic behavior of a Nitinol cubic block

    Science.gov (United States)

    Chiroiu, Veturia; Florinel Ionescu, Marius; Sireteanu, Tudor; Ioan, Rodica; Munteanu, Ligia

    2015-03-01

    In this paper, the cyclic behavior of a superelastic-plastic nitinol cubic block is described by using the Bouc-Wen model coupled to an intrinsic time measure other than clock time, which governs the behavior of the materials. As a consequence, the thermodynamic admissibility of the Bouc-Wen model is provided by the endochronic theory of plasticity. The role of the intrinsic time measure is described by capturing the stiffness and strength degradation and the opposite phenomena. Such behavior is due to the permanent-strain addition of residual martensite and alterations in the properties of the texture during phase transformation.

  16. Cyclic Behavior of Mortarless Brick Joints with Different Interlocking Shapes

    Directory of Open Access Journals (Sweden)

    Hongjun Liu

    2016-03-01

    Full Text Available The framed structure infilled with a mortarless brick (MB panel exhibits considerable in-plane energy dissipation because of the relative sliding between bricks and good out-of-plane stability resulting from the use of interlocking mechanisms. The cyclic behaviors of MB are investigated experimentally in this study. Two different types of bricks, namely non-interlocking mortarless brick (N-IMB and interlocking mortarless brick (IMB, are examined experimentally. The cyclic behavior of all of the joints (N-IMB and IMB are investigated in consideration of the effects of interlocking shapes, loading compression stress levels and loading cycles. The hysteretic loops of N-IMB and IMB joints are obtained, according to which a mechanical model is developed. The Mohr–Coulomb failure criterion is employed to describe the shear failure modes of all of the investigated joints. A typical frictional behavior is observed for the N-IMB joints, and a significant stiffening effect is observed for the IMB joints during their sliding stage. The friction coefficients of all of the researched joints increase with the augmentation of the compression stress level and improvement of the smoothness of the interlocking surfaces. An increase in the loading cycle results in a decrease in the friction coefficients of all of the joints. The degradation rate (DR of the friction coefficients increases with the reduction in the smoothness of the interlocking surface.

  17. Coevolutionary dynamics with clustering behaviors on cyclic competition

    Science.gov (United States)

    Dong, Linrong; Yang, Guangcan

    2012-05-01

    We propose a dynamic model for describing clustering behaviors on a cyclic game, in which the same species form a cluster to compete. The rates of consuming the prey depend not only on the individual competing ability v, but also on the two interacting cluster’s sizes. The fragmentation and coagulation rates of the clusters are related to the cohesive strength among the individuals. A new parameter u is introduced to indicate the uniting degree. We find that the probability distribution of the clustering sizes is almost a power law in a large regime specified by the two parameters, which reflects the scale-free behavior in complex systems. In addition, the exponential magnitudes are mostly in the range of real social systems. Our simulation shows that clustering promotes biodiversity. At steady state, the amounts about the three species evolve tempestuously with asymmetric period; the aggregations about big size’s clusters to compete are obvious and on-off intermittence.

  18. Large strain cyclic behavior of metastable austenic stainless steel

    Energy Technology Data Exchange (ETDEWEB)

    Geijselaers, H.J.M., E-mail: h.j.m.geijselaers@utwente.nl; Hilkhuijsen, P.; Bor, T.C.; Boogaard, A.H. van den

    2015-04-17

    Metastable austenitic stainless steel will transform to martensite when subjected to mechanical working. In this research an austenitic stainless steel has been subjected to large amplitude strain paths containing a strain reversal. During the tests, apart from the stress and the strain also magnetic induction was measured. From the in situ magnetic induction measurements an estimate of the stress partitioning among the phases is determined. When the strain path reversal is applied at low strains, a classical Bauschinger effect is observed. When the strain reversal is applied at higher strains, a higher flow stress is measured after the reversal compared to the flow stress before reversal. Also a stagnation of the transformation is observed, meaning that a higher strain as well as a higher stress than before the strain path change is required to restart the transformation after reversal. The observed behavior can be explained by a model in which for the martensitic transformation a stress induced transformation model is used. The constitutive behavior of both the austenite phase and the martensite is described by a Chaboche model to account for the Bauschinger effect. Mean-field homogenization of the material behavior of the individual phases is employed to obtain a constitutive behavior of the two-phase composite. The overall applied stress, the stress in the martensite phase and the observed transformation behavior during cyclic shear are very well reproduced by the model simulations.

  19. Modeling the Cyclic Behavior of Shape Memory Alloys

    Science.gov (United States)

    Waimann, Johanna; Junker, Philipp; Hackl, Klaus

    2017-06-01

    The phenomenon of functional fatigue occurs during cyclic loading of pseudoelastic shape memory alloys. We model this effect by considering an irreversible martensitic volume fraction in addition to the reversible amounts of austenite and martensite based on variational principles. The inclusion of irreversible martensitic volume fractions coincides with experimental observations and enables the model to be easily calibrated without any fitting functions. In our previous studies, we modeled the polycrystalline material structure by static discretization of a relatively large number of randomly chosen grain orientations, which required much numerical effort. In contrast, we now apply a dynamic representation of the orientation distribution function to the modeling of functional fatigue which has proven to be beneficial regarding the numerical performance. To this end, we take into account an averaged grain orientation parameterized by three Euler angles that serve as additional internal variables. This results in an extremely reduced numerical effort. The model derivation is given along with the numerical implementation and computer experiments on the cyclic behavior of shape memory alloys.

  20. Manifest and Subtle Cyclic Behavior in Nonequilibrium Steady States

    CERN Document Server

    Zia, R K P; Mandal, Dibyendu; Fox-Kemper, Baylor

    2016-01-01

    Many interesting phenomena in nature are described by stochastic processes with irreversible dynamics. To model these phenomena, we focus on a master equation or a Fokker-Planck equation with rates which violate detailed balance. When the system settles in a stationary state, it will be a nonequilibrium steady state (NESS), with time independent probability distribution as well as persistent probability current loops. The observable consequences of the latter are explored. In particular, cyclic behavior of some form must be present: some are prominent and manifest, while others are more obscure and subtle. We present a theoretical framework to analyze such properties, introducing the notion of "probability angular momentum" and its distribution. Using several examples, we illustrate the manifest and subtle categories and how best to distinguish between them. These techniques can be applied to reveal the NESS nature of a wide range of systems in a large variety of areas. We illustrate with one application: var...

  1. Cyclic behavior of solar inter-network magnetic field

    CERN Document Server

    Jin, Chunlan

    2015-01-01

    Solar inter-network magnetic field is the weakest component of solar magnetism, but contributes most of the solar surface magnetic flux. The study on its origin has been constrained by the inadequate tempo-spatial resolution and sensitivity of polarization observations. With dramatic advances in spatial resolution and detective sensitivity, solar spectro-polarimetry provided by the Solar Optical Telescope aboard Hinode in an interval from solar minimum to maximum of cycle 24 opens an unprecedented opportunity to study the cyclic behavior of solar inter-network magnetic field. More than 1000 Hinode magnetograms observed from 2007 January to 2014 August are selected in the study. It has been found that there is a very slight correlation between sunspot number and magnetic field at the inter-network flux spectrum. From solar minimum to maximum of cycle 24, the flux density of solar inter-network field is invariant, which is 10$\\pm1$ G. The observations suggest that the inter-network magnetic field does not arise...

  2. The Cyclic Deformation Behavior of Severe Plastic Deformation (SPD Metals and the Influential Factors

    Directory of Open Access Journals (Sweden)

    Charles C. F. Kwan

    2012-02-01

    Full Text Available A deeper understanding of the mechanical behavior of ultra-fine (UF and nanocrystalline (NC grained metals is necessary with the growing interest in using UF and NC grained metals for structural applications. The cyclic deformation response and behavior of UF and NC grained metals is one aspect that has been gaining momentum as a major research topic for the past ten years. Severe Plastic Deformation (SPD materials are often in the spotlight for cyclic deformation studies as they are usually in the form of bulk work pieces and have UF and NC grains. Some well known techniques in the category of SPD processing are High Pressure Torsion (HPT, Equal Channel Angular Pressing (ECAP, and Accumulative Roll-Bonding (ARB. In this report, the literature on the cyclic deformation response and behavior of SPDed metals will be reviewed. The cyclic response of such materials is found to range from cyclic hardening to cyclic softening depending on various factors. Specifically, for SPDed UF grained metals, their behavior has often been associated with the observation of grain coarsening during cycling. Consequently, the many factors that affect the cyclic deformation response of SPDed metals can be summarized into three major aspects: (1 the microstructure stability; (2 the limitation of the cyclic lifespan; and lastly (3 the imposed plastic strain amplitude.

  3. CYCLIC HARDENING BEHAVIOR OF POLYCRYSTALS WITH PENETRABLE GRAIN BOUNDARIES: TWO-DIMENSIONAL DISCRETE DISLOCATION DYNAMICS SIMULATION

    Institute of Scientific and Technical Information of China (English)

    Chuantao Hou; Zhenhuan Li; Minsheng Huang; Chaojun Ouyang

    2009-01-01

    A two-dimensional discrete dislocation dynamics (DDD) technology by Giessen and Needleman (1995), which has been extended by integrating a dislocation-grain boundary interaction model, is used to computationally analyze the micro-cyclic plastic response of polycrystals containing micron-sized grains, with special attentions to significant influence of dislocationpenetrable grain boundaries (GBs) on the micro-plastic cyclic responses of polycrystals and underlying dislocation mechanism. Toward this end, a typical polycrystalline rectangular specimen under simple tension-compression loading is considered. Results show that, with the increase of cycle accumulative strain, continual dislocation accumulation and enhanced dislocation-dislocation interactions induce the cyclic hardening behavior; however, when a dynamic balance among dislocation nucleation, penetration through GB and dislocation annihilation is approximately established, cyclic stress gradually tends to saturate. In addition, other factors, including the grain size, cyclic strain amplitude and its history, also have considerable influences on the cyclic hardening and saturation.

  4. Analysis of the cyclic behavior and fatigue damage of extruded AA2017 aluminum alloy

    Energy Technology Data Exchange (ETDEWEB)

    May, A., E-mail: abdelghani1980@yahoo.fr [INSA/GPM, CNRS UMR 6634, BP 08 avenue de l' université, 76801 Saint Etienne du Rouvray Cedex (France); Laboratoire Génie des Matériaux, Ecole Militaire Polytechnique, BP 17 Bordj El-Bahri Algiers (Algeria); Taleb, L., E-mail: lakhdar.taleb@insa-rouen.fr [INSA/GPM, CNRS UMR 6634, BP 08 avenue de l' université, 76801 Saint Etienne du Rouvray Cedex (France); Belouchrani, M.A., E-mail: nbelouch@yahoo.fr [Laboratoire Génie des Matériaux, Ecole Militaire Polytechnique, BP 17 Bordj El-Bahri Algiers (Algeria)

    2013-06-01

    The present work is devoted to study the anisotropic behavior of an extruded aluminum alloy under cyclic loading in axial and shear directions. In first, we have studied its elastoplastic behavior through the evolution of stress–strain loops, isotropic and kinematic hardening and we have associated this behavior with the evolution of its elastic adaptation (shakedown). In second, we have studied the behavior of the material in fatigue damage using the evolution of stiffness. Finally, microstructural investigations were performed on fractured surfaces using scanning electron microscope (SEM) in order to understand the evolution of fatigue damage during cyclic loading.

  5. Molecular Simulations of Cyclic Loading Behavior of Carbon Nanotubes Using the Atomistic Finite Element Method

    Directory of Open Access Journals (Sweden)

    Jianfeng Wang

    2009-01-01

    Full Text Available The potential applications of carbon nanotubes (CNT in many engineered bionanomaterials and electromechanical devices have imposed an urgent need on the understanding of the fatigue behavior and mechanism of CNT under cyclic loading conditions. To date, however, very little work has been done in this field. This paper presents the results of a theoretical study on the behavior of CNT subject to cyclic tensile and compressive loads using quasi-static molecular simulations. The Atomistic Finite Element Method (AFEM has been applied in the study. It is shown that CNT exhibited extreme cyclic loading resistance with yielding strain and strength becoming constant within limited number of loading cycles. Viscoelastic behavior including nonlinear elasticity, hysteresis, preconditioning (stress softening, and large strain have been observed. Chiral symmetry was found to have appreciable effects on the cyclic loading behavior of CNT. Mechanisms of the observed behavior have been revealed by close examination of the intrinsic geometric and mechanical features of tube structure. It was shown that the accumulated residual defect-free morphological deformation was the primary mechanism responsible for the cyclic failure of CNT, while the bond rotating and stretching experienced during loading/unloading played a dominant role on the strength, strain and modulus behavior of CNT.

  6. Work-hardening behavior of mild steel under cyclic deformation at finite strains

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Z. (Univ. Paris-Nord, Villetaneuse (France))

    1994-10-01

    The work-hardening behavior of mild steel under monotonic deformation at large shears and cyclic deformation under a wide range of shear amplitudes (from 3 to 34%) has been experimentally investigated and modeled. The influence of shear amplitude, the effect of the amount of pre-shear and that of pre-cyclic deformation have been studied. Considering the evolution of both polarized persistent dislocation structures and no-polarized low-energy dislocation configurations, a physically-based phenomenological model with four internal variables has been proposed. The model explains the cyclic hardening behavior at large strains, the work-hardening stagnation followed by a resumption of work-hardening under Bauschinger deformation with large pre-strains and under cyclic deformation with moderate strain amplitudes. A good qualitative and quantitative agreement has been achieved between experimental results and model predictions.

  7. Cyclic AMP-dependent memory mutants are defective in the food choice behavior of Drosophila.

    Science.gov (United States)

    Motosaka, Katsunori; Koganezawa, Masayuki; Narikawa, Satoko; Furuyama, Akira; Shinozaki, Kenji; Isono, Kunio; Shimada, Ichiro

    2007-02-01

    Acute choice behavior in ingesting two different concentrations of sucrose in Drosophila is presumed to include learning and memory. Effects on this behavior were examined for four mutations that block associative learning (dunce, rutabaga, amnesiac, and radish). Three of these mutations cause cyclic AMP signaling defects and significantly reduced taste discrimination. The exception was radish, which affects neither. Electrophysiological recordings confirmed that the sensitivity of taste receptors is almost indistinguishable in all flies, whether wild type or mutant. These results suggest that food choice behavior in Drosophila involves central nervous learning and memory operating via cyclic AMP signaling pathways.

  8. Behavioral effects of cyclic changes in serotonin during the human menstrual cycle.

    Science.gov (United States)

    Warren, D E; Tedford, W H; Flynn, W E

    1979-03-01

    Many cyclic changes during the menstrual cycle (temperature, depression, motor activity, pain sensitivity, etc.) are closely paralleled by changes in brain serotonin level. These changes, in turn, are associated with peripheral hormone levels which are comparatively regular and easily measured. Their measurement may be useful both in predicting behavior and in accounting for atypical menstrual-related behavior.

  9. Characterizing and modeling cyclic behavior in non-stationary time series through multi-resolution analysis

    CERN Document Server

    Ahalpara, D P; Parikh, J C; Verma, A; Ahalpara, Dilip P.; Panigrahi, Prasanta K.; Parikh, Jitendra C.; Verma, Amit

    2006-01-01

    A method based on wavelet transform and genetic programming is proposed for characterizing and modeling variations at multiple scales in non-stationary time series. The cyclic variations, extracted by wavelets and smoothened by cubic splines, are well captured by genetic programming in the form of dynamical equations. For the purpose of illustration, we analyze two different non-stationary financial time series, S&P CNX Nifty closing index of the National Stock Exchange (India) and Dow Jones industrial average closing values through Haar, Daubechies-4 and continuous Morlet wavelets for studying the character of fluctuations at different scales, before modeling the cyclic behavior through GP. Cyclic variations emerge at intermediate time scales and the corresponding dynamical equations reveal characteristic behavior at different scales.

  10. Precipitation under cyclic strain in solution-treated Al4wt%Cu I: mechanical behavior

    Energy Technology Data Exchange (ETDEWEB)

    Farrow, Adam M [Los Alamos National Laboratory; Laird, Campbell [UNIV OF PENNSYLVANIA

    2008-01-01

    Solution-treated AL-4wt%Cu was strain-cycled at ambient temperature and above, and the precipitation and deformation behaviors investigated by TEM. Anomalously rapid growth of precipitates appears to have been facilitated by a vacancy super-saturation generated by cyclic strain and the presence of a continually refreshed dislocation density to provide heterogeneous nucleation sites. Texture effects as characterized by Orientation Imaging Microscopy appear to be responsible for latent hardening in specimens tested at room temperature, with increasing temperatures leading to a gradual hardening throughout life due to precipitation. Specimens exhibiting rapid precipitation hardening appear to show a greater effect of texture due to the increased stress required to cut precipitates in specimens machined from rolled plate at an angle corresponding to a lower average Schmid factor. The accelerated formation of grain boundary precipitates appears to be partially responsible for rapid inter-granular fatigue failure at elevated temperatures, producing fatigue striations and ductile dimples coexistent on the fracture surface.

  11. Inelastic behavior of cold-formed braced walls under monotonic and cyclic loading

    Science.gov (United States)

    Gerami, Mohsen; Lotfi, Mohsen; Nejat, Roya

    2015-06-01

    The ever-increasing need for housing generated the search for new and innovative building methods to increase speed and efficiency and enhance quality. One method is the use of light thin steel profiles as load-bearing elements having different solutions for interior and exterior cladding. Due to the increase in CFS construction in low-rise residential structures in the modern construction industry, there is an increased demand for performance inelastic analysis of CFS walls. In this study, the nonlinear behavior of cold-formed steel frames with various bracing arrangements including cross, chevron and k-shape straps was evaluated under cyclic and monotonic loading and using nonlinear finite element analysis methods. In total, 68 frames with different bracing arrangements and different ratios of dimensions were studied. Also, seismic parameters including resistance reduction factor, ductility and force reduction factor due to ductility were evaluated for all samples. On the other hand, the seismic response modification factor was calculated for these systems. It was concluded that the highest response modification factor would be obtained for walls with bilateral cross bracing systems with a value of 3.14. In all samples, on increasing the distance of straps from each other, shear strength increased and shear strength of the wall with bilateral bracing system was 60 % greater than that with lateral bracing system.

  12. Low Cycle Fatigue Behavior of 316LN Stainless Steel Alloyed with Varying Nitrogen Content. Part I: Cyclic Deformation Behavior

    Science.gov (United States)

    Prasad Reddy, G. V.; Sandhya, R.; Sankaran, S.; Mathew, M. D.

    2014-10-01

    In this study, the influence of cyclic strain amplitude on the evolution of cyclic stress-strain response and the associated cyclic deformation mechanisms in 316LN stainless steel with varying nitrogen content (0.07 to 0.22 wt pct) is reported in the temperature range 773 K to 873 K (500 °C to 600 °C). Two mechanisms, namely dynamic strain aging and secondary cyclic hardening, are found to strongly influence the cyclic stress response. Deformation substructures associated with both the mechanisms showed planar mode of deformation. These mechanisms are observed to be operative over certain combinations of temperature and strain amplitude. For strain amplitudes >0.6 pct, wavy or mixed mode of deformation is noticed to suppress both the mechanisms. Cyclic stress-strain curves revealed both single and dual-slope behavior depending on the test temperature. Increase in nitrogen content is found to increase the tendency toward planar mode of deformation, while increase in strain amplitude leads to transition from planar slip bands to dislocation cell/wall structure formation, irrespective of the nitrogen content in 316LN stainless steel.

  13. Modeling and cyclic behavior of segmental bridge column connected with shape memory alloy bars

    Science.gov (United States)

    Roh, Hwasung; Reinhorn, Andrei M.; Lee, Jong Seh

    2012-09-01

    This paper examines the quasi-static cyclic behavior, lateral strength and equivalent damping capacities of a system of post-tensioned segmental bridge columns tied with large diameter martensitic Shape Memory Alloy (SMA) link-bars. Moment-curvature constitutive relationships are formulated and analysis tools are developed for the PT column, including a modified four-spring model prepared for the SMA bars. The suggested system is exemplified using a column with an aspect ratio of 7.5 and twelve 36.5 mm diameter NiTi martensitic SMA bars. A post-tensioning force of 40% to 60% of the tendon yield strength is applied in order to obtain a self re-centering system, considering the residual stress of the martensitic SMA bars. The cyclic response results show that the lateral strength remains consistently around 10% of the total vertical load and the equivalent viscous damping ratios reach 10%-12% of critical. When large diameter NiTi superelastic SMA bars are incorporated into the column system, the cyclic response varies substantially. The creep behavior of the superelastic SMA bar is accounted for since it affects the re-centering capability of the column. Two examples are presented to emphasize the modeling sensitivities for these special bars and quantify their cyclic behavior effects within the column assembly.

  14. Using dynamic mode decomposition to extract cyclic behavior in the stock market

    Science.gov (United States)

    Hua, Jia-Chen; Roy, Sukesh; McCauley, Joseph L.; Gunaratne, Gemunu H.

    2016-04-01

    The presence of cyclic expansions and contractions in the economy has been known for over a century. The work reported here searches for similar cyclic behavior in stock valuations. The variations are subtle and can only be extracted through analysis of price variations of a large number of stocks. Koopman mode analysis is a natural approach to establish such collective oscillatory behavior. The difficulty is that even non-cyclic and stochastic constituents of a finite data set may be interpreted as a sum of periodic motions. However, deconvolution of these irregular dynamical facets may be expected to be non-robust, i.e., to depend on specific data set. We propose an approach to differentiate robust and non-robust features in a time series; it is based on identifying robust features with reproducible Koopman modes, i.e., those that persist between distinct sub-groupings of the data. Our analysis of stock data discovered four reproducible modes, one of which has period close to the number of trading days/year. To the best of our knowledge these cycles were not reported previously. It is particularly interesting that the cyclic behaviors persisted through the great recession even though phase relationships between stocks within the modes evolved in the intervening period.

  15. Mechanical Behavior of Two High Strength Alloy Steels Under Conditions of Cyclic Tension

    Science.gov (United States)

    Srivatsan, T. S.; Manigandan, K.; Sastry, S.; Quick, T.; Schmidt, M. L.

    2014-01-01

    The results of a recent study aimed at understanding the conjoint influence of load ratio and microstructure on the high cycle fatigue properties and resultant fracture behavior of two high strength alloy steels is presented and discussed. Both the chosen alloy steels, i.e., 300M and Tenax™ 310 have much better strength and ductility properties to offer in comparison with the other competing high strength steels having near similar chemical composition. Test specimens were precision machined from the as-provided stock of each steel. The machined specimens were deformed in both uniaxial tension and cyclic fatigue under conditions of stress control. The test specimens of each alloy steel were cyclically deformed over a range of maximum stress at two different load ratios and the number of cycles to failure recorded. The specific influence of load ratio on cyclic fatigue life is presented and discussed keeping in mind the maximum stress used during cyclic deformation. The fatigue fracture surfaces were examined in a scanning electron microscope to establish the macroscopic mode and to concurrently characterize the intrinsic features on the fracture surface. The conjoint influence of nature of loading, maximum stress, and microstructure on cyclic fatigue life is discussed.

  16. Influence of cyclic frequency on oxidation behavior of K38 superalloy with yttrium additions at 1 273 K

    Institute of Scientific and Technical Information of China (English)

    YU Ping; WANG Wen; WANG Fuhui

    2011-01-01

    Cyclic oxidation test is a fundamental method to assess lifetime of materials in high temperature environment. Cycle length or cyclic frequency is one important variable in cyclic oxidation testing. In present work, cyclic oxidation tests were performed on cast K38 alloys with 0 wt.%, 0.1 wt.%, and 0.5 wt.% yttrium additions at 1 273 K respectively. Two cyclic frequencies were used to investigate the influence of cycle length (1 h vs. 20 h) on the high temperature oxidation behavior of superalloy. The results showed that the degradation of cast K38alloy critically was dependent on the cyclic frequency. The yttrium addition was beneficial to reducing scale-growth rate, improving the scale adhesion and stress releasing, thereby increased the spallation resistance. It could be drawn that the effect of cyclic frequency was highly dependent on the scale adherence to the substrate.

  17. Mechanical Behavior of AZ31B Mg Alloy Sheets under Monotonic and Cyclic Loadings at Room and Moderately Elevated Temperatures

    Directory of Open Access Journals (Sweden)

    Ngoc-Trung Nguyen

    2014-02-01

    Full Text Available Large-strain monotonic and cyclic loading tests of AZ31B magnesium alloy sheets were performed with a newly developed testing system, at different temperatures, ranging from room temperature to 250 °C. Behaviors showing significant twinning during initial in-plane compression and untwinning in subsequent tension at and slightly above room temperature were recorded. Strong yielding asymmetry and nonlinear hardening behavior were also revealed. Considerable Bauschinger effects, transient behavior, and variable permanent softening responses were observed near room temperature, but these were reduced and almost disappeared as the temperature increased. Different stress–strain responses were inherent to the activation of twinning at lower temperatures and non-basal slip systems at elevated temperatures. A critical temperature was identified to account for the transition between the twinning-dominant and slip-dominant deformation mechanisms. Accordingly, below the transition point, stress–strain curves of cyclic loading tests exhibited concave-up shapes for compression or compression following tension, and an unusual S-shape for tension following compression. This unusual shape disappeared when the temperature was above the transition point. Shrinkage of the elastic range and variation in Young’s modulus due to plastic strain deformation during stress reversals were also observed. The texture-induced anisotropy of both the elastic and plastic behaviors was characterized experimentally.

  18. Shear Behavior of Novel Prestressed Concrete Beam Subjected to Monotonic and Cyclic Loading

    Institute of Scientific and Technical Information of China (English)

    余芳; 姚大立; 贾金青; 吴锋

    2014-01-01

    Prestressed steel ultrahigh-strength reinforced concrete (PSURC) beam is a new type of prestressed con-crete beam, which not only has a considerable compressive strength attributed to the ultrahigh strength concrete, but also ensures a certain degree of ductility at failure due to the existence of structural steel. Five of these beams were monotonically tested until shear failure to investigate the static shear performance including the failure pattern, load-deflection behavior, shear capacity, shear crack width and shear ductility. The experimental results show that these beams have superior shear capacity, crack control ability and shear ductility. To study the shear performance under repeated overloading, seven PSURC beams were loaded in cyclic test simultaneously. The overall shear performance of cycled beams is similar to that of uncycled beams at low load level but different at high load level. The shear capac-ity and crack control ability of cycled beams at high load level are reduced, whereas the shear ductility is improved. In addition, the influences of variables including the degree of prestress, stirrup ratio and load level on the shear perform-ance of both uncycled and cycled beams were also discussed and compared, respectively.

  19. Cyclic behavior test of a new double-arch steel gate

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A new double-arch structure for the gate used as tidal barrage and sluice was adopted in Caoe River Dam in China. It was a spatial structure made up of the right arch, the invert arch, the chord, etc., and was designed to bear bilateral loads. To research the cyclic behavior of the new double-arch structure, a scale-model cyclic test was conducted. First, the test setup and test method were presented in detail, and according to the test results, the cyclic behavior and failure characteristics of this structure were discussed. Then by analyzing the test cyclic envelope curve, it was found the curve was divided into three stages: the elastic stage, the local plastic stage and the failure stage at the local yield point and structural yield point. The gate model has local yield strength and structural yield strength, with both their values being bigger than that of the designing load. Therefore, the gate is safe enough for the projects. At last, dynamic property of the gate was analyzed considering additional mass of the water. It was found that the tidal bore shock would not cause resonance vibration of the gate.

  20. Modest effects of repeated fluoxetine on estrous cyclicity and sexual behavior in Sprague Dawley female rats.

    Science.gov (United States)

    Maswood, Navin; Sarkar, Jhimly; Uphouse, Lynda

    2008-12-15

    In an earlier study, we reported that daily fluoxetine treatment (10 mg/kg/day) rapidly disrupted estrous cyclicity and sexual receptivity in adult, regularly cycling Fischer rats. The current study was designed to investigate if comparable fluoxetine treatment would similarly affect intact, regularly cycling Sprague Dawley rats. In the first experiment, fluoxetine was injected for 24 days. After 11-14 days of daily fluoxetine treatment, 40% of the rats showed a transient disturbance of the estrous cycle with elimination of sexual receptivity. In these affected rats, reduced sexual receptivity generally preceded disruption of vaginal cyclicity. In a second experiment, a shorter exposure was used to attempt to dissociate effects of fluoxetine on behavior and estrous cyclicity. Nine days of fluoxetine treatment eliminated sexual receptivity and proceptivity (hops/darts) in 40% and 46%, respectively, of rats without altering the estrous cycle. Female rats then received a 10th fluoxetine injection 30 min prior to assessment of sexual motivation (measured with the male preference paradigm). There was no effect of fluoxetine on male preference, but fluoxetine significantly reduced the number of crossings and seconds of grooming during preference testing. Therefore, effects of fluoxetine on estrous cyclicity and behavior of Sprague Dawley female rats were smaller and required longer to develop than previously reported in Fischer female rats. These findings reinforce a probable relationship between fluoxetine's effect on sexual activity and neuroendocrine disturbances and illustrate the importance of strain selection in attempting to model human disease.

  1. Cell behavior in Dictyostelium discoideum: preaggregation response to localized cyclic AMP pulses.

    Science.gov (United States)

    Futrelle, R P; Traut, J; McKee, W G

    1982-03-01

    The motion of cells in the aggregation phase of Dictyostelium discoideum development is complex. To probe its mechanisms we applied precisely timed (+/- 1 s) and positioned (+/-2 micrometers) pulses of cyclic AMP to fields of cells of moderate density using a micropipette. We recorded cell behavior by time lapse microcinematography and extracted cell motion data from the film with our Galatea computer system. Analysis of these data reveals: (a) Chemotaxis lasts only about as long as the cyclic AMP signal; in particular, brief pulses (approximately 5 s) do not induce chemotaxis. (b) Chemotactic competence increases gradually from within an hour after the initiation of development (starvation) to full competence at approximately 15 h when aggregation begins under our conditions. (c) Cell motion reverses rapidly (within 20 s) when the external gradient is reversed. There is no refractory period for motion. We present a new description of the process of aggregation consistent with our result and other recent findings. (d) The behavioral response to cyclic AMP includes a phenomenon we call "cringing." In a prototypical cringe the cell speed drops within 3 s after a brief cyclic AMP stimulus, and the cell stops and rounds and then resumes motion after 25 s. (e) The development of the speed response in cringing as the cells age closely parallels the development of the cyclic AMP-induced light-scattering response of cells in suspension. (f) Cringing occurs in natural populations during weak oriented movement. The computerized analysis of cell behavior proves to be a powerful technique which can reveal significant phenomena that are not apparent to the eye even after repeated examination of the film.

  2. Investigation on hardening behavior of metallic glass under cyclic indentation loading via molecular dynamics simulation

    Science.gov (United States)

    Zhao, Dan; Zhao, Hongwei; Zhu, Bo; Wang, Shunbo

    2017-09-01

    Mechanical behavior of a Cu-Zr metallic glass (MG) under cyclic indentation loading is investigated via molecular dynamics simulation. A large-depth indentation after cycling is conducted, and the indentation curves show that hardening behavior occurs with cyclic indentation amplitudes exceeding elastic range. The atomic Von Mises shear strain distributions during the large-depth indentation are investigated, and the pre-existing plastic deformation induced by cyclic indentation is found to be the main contributor to the hardening behavior. By monitoring the atom trajectories and Voronoi atom volume, structure densification and free volume reduction phenomenon are found in the area beneath indenter after cycles. The accumulations of irreversible shear strain during cycling induce the area beneath indenter experience atom structure transition and become densified, thus the sample becomes more resistant to further deformation. In addition, the effects of temperatures and loading rates on the hardening behavior are studied. With higher temperature, more homogenous deformation and plasticity are produced, and then inducing more severe hardening in the MG. While with lower loading rate, the hardening phenomenon is found to be less severe because of the localization of shear strain during cycling.

  3. Experimental research on seismic behavior of recycled concrete frame under varying cyclic loading

    Institute of Scientific and Technical Information of China (English)

    Yuedong SUN; Jianzhuang; XIAO Research

    2008-01-01

    A study is conducted on the seismic behavior of one natural concrete frame and two recycled concrete frames with 100% recycled coarse aggregate whose scales are 1:2 entirely, and a comparative study is conducted under low-reversed cyclic lateral loading and different ver-tical loading. This work aims to estimate the failure mech-anism, hysteresis loops, displacement ductility, deterioration of strength and stiffness and energy dissipa-tion of recycled concrete frames under low-reversed cyclic loading as well as the influence of different vertical load-ing. Analysis on the basis of the experiment proves that it is entirely feasible to apply recycled concrete to practical engineering for the sake of its good seismic behaviors. Theoretical base is provided for further study and prac-tical application of recycled concrete structure.

  4. Inelastic behavior of materials and structures under monotonic and cyclic loading

    CERN Document Server

    Brünig, Michael

    2015-01-01

    This book presents studies on the inelastic behavior of materials and structures under monotonic and cyclic loads. It focuses on the description of new effects like purely thermal cycles or cases of non-trivial damages. The various models are based on different approaches and methods and scaling aspects are taken into account. In addition to purely phenomenological models, the book also presents mechanisms-based approaches. It includes contributions written by leading authors from a host of different countries.

  5. BASIC STUDY ON TENSION SOFTENING AND CYCLIC DEFORMATION BEHAVIOR OF SOLIDIFIED BODY FOR THE COHESIVE SOIL

    Science.gov (United States)

    Urano, Kazuhiko; Adachi, Yuji; Mihara, Masaya; Yamada, Atsuo; Kawamura, Makoto

    So far, authors have proposed a method to improve earthquake resistance of pile foundations by partially solidifying an underground part of the pile foundations, and the effect of reinforcement has been confirmed by shaking table tests and the lateral loading tests of a full scale model. Though the solidified body is usually designed as an elastic body, it is possible to design the body considering the damage by the tensile stress when a seismic ground motion is assumed to be level 2. Therefore, material tests of the solidified body for the cohesive soil were executed, and the characteristics of the tension softening and the cyclic deformation behavior of the solidified bod y were clarified. Moreover, loading tests that used wall models of the solidified body were executed, and the effects of the shape on the tension softening and the cyclic deformation behavior of the solidified body were clarified. In addition, a numerical simulation by elastoplastic FEM analysis that considers the damage of the solidified body was executed, and the tension softening and the cyclic deformation behavior of the solidified body were reproduced.

  6. Long-Term Cyclic Oxidation Behavior of Wrought Commercial Alloys at High Temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Bingtao Li

    2003-08-05

    The oxidation resistance of a high-temperature alloy is dependent upon sustaining the formation of a protective scale, which is strongly related to the alloying composition and the oxidation condition. The protective oxide scale only provides a finite period of oxidation resistance owing to its eventual breakdown, which is especially accelerated under thermal cycling conditions. This current study focuses on the long-term cyclic oxidation behavior of a number of commercial wrought alloys. The alloys studied were Fe- and Ni-based, containing different levels of minor elements, such as Si, Al, Mn, and Ti. Oxidation testing was conducted at 1000 and 1100 C in still air under both isothermal and thermal cycling conditions (1-day and 7-days). The specific aspects studied were the oxidation behavior of chromia-forming alloys that are used extensively in industry. The current study analyzed the effects of alloying elements, especially the effect of minor element Si, on cyclic oxidation resistance. The behavior of oxide scale growth, scale spallation, subsurface changes, and chromium interdiffusion in the alloy were analyzed in detail. A novel model was developed in the current study to predict the life-time during cyclic oxidation by simulating oxidation kinetics and chromium interdiffusion in the subsurface of chromia-forming alloys.

  7. Monotonic and Cyclic Bond Behavior of Deformed CFRP Bars in High Strength Concrete

    Directory of Open Access Journals (Sweden)

    T. Tibet Akbas

    2016-05-01

    Full Text Available Composite reinforcing bars (rebars that are used in concrete members with high performance (strength and durability properties could have beneficial effects on the behavior of these members. This is especially vital when a building is constructed in an aggressive environment, for instance a corrosive environment. Although tension capacity/weight (or volume ratios in composite rebars (carbon fiber reinforced polymer (CFRP, glass fiber reinforced polymer (GFRP, etc. are very high when compared to steel rebars, major weaknesses in concrete members reinforced with these composite rebars may be the potential consequences of relatively poor bonding capacity. This may even be more crucial when the member is subjected to cyclic loading. Although monotonic bond tests are available in the literature, only limited experimental studies exist on bond characteristics under cyclic loading conditions. In order to fill this gap and propose preliminary design recommendations, 10 specimens of 10-mm-diameter ribbed CFRP rebars embedded in specially designed high strength concrete (f’c = 70 MPa blocks were subjected to monotonic and cyclic pullout tests. The experimental results showed that cyclically loaded CFRP rebars had less bond strength than those companion specimens loaded monotonically.

  8. Micro-mechanical behavior of porous tungsten/Zr-based metallic glass composite under cyclic compression

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, X.Q. [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Xue, Y.F., E-mail: xueyunfei@bit.edu.cn [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Wang, L.; Fan, Q.B.; Nie, Z.H. [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Zhang, H.F.; Fu, H.M. [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China)

    2015-09-03

    The micro-mechanical behavior of porous tungsten/Zr-based metallic glass composites with different tungsten volume fraction was investigated under cyclic compression by synchrotron-based in-situ high-energy X-ray diffraction (HEXRD) and finite element modeling (FEM). During cyclic compression, the dislocation in the tungsten phase tangled near the interfaces, indicating that the elastic metallic glass phase restricted dislocation motion and obstructed the deformation of the tungsten phase because of the heterogeneity in stress. After the metallic glass phase yielded, the dislocation tended to propagate away from the interfaces, showing the decrease of the interphase stress affected the direction of motion in the dislocations. The tungsten phase exhibited increased yield strength with the increase of cyclic loading number. Yield stress of the tungsten phase decreased with increasing the tungsten volume fraction during cyclic compression, which was influenced by the elastic strain mismatch between the two phases. The stress heterogeneity and the stress distribution difference between the two phases resulted in that the yield strength of the metallic glass phase decreased with the increase of tungsten volume fraction, and accelerated the formation of shear bands in the metallic glass phase as well as cracks in the tungsten phase. The heterogeneity in stress also excessed the interface bonding strength, inducing interface fracture near interfaces.

  9. Correlation between the Cyclic Stress Behavior and Microstructure in 316LN based on the Analysis of Hysteresis Loops

    Institute of Scientific and Technical Information of China (English)

    CHANG Bo; ZHANG Zheng

    2014-01-01

    Total strain controlled cyclic test was performed on 316LN under uniaxial loadings. Through the partitioning of hysteresis loops, the evolution of two components of cyclic flow stress, the internal and effective stresses, was reported. The former one determines the cyclic stress response. Based on the transmission electron microscopic (TEM) observation on specimens loaded with scheduled cycles, it is found that planar dislocation structures prevail during the entire cyclic process at low strain amplitude, while a remarkable dislocation rearrangement from planar structures to heterogeneous spatial distributions is companied by a cyclic softening behavior at high strain amplitude. The competition between the evolution of the intergranular and the intragranular components of the internal stress caused by the transition of slip mode induces the cyclic hardening and softening at high strain levels. The intergranular internal stress represents the most part of the internal stress at low strain level.

  10. A new bounding-surface plasticity model for cyclic behaviors of saturated clay

    Science.gov (United States)

    Hu, Cun; Liu, Haixiao

    2015-05-01

    A new combined isotropic-kinematic hardening rule is proposed based on the concept of the generalized homological center and the generalization of Masing's rule. The key point of the new hardening rule is that the unloading event can be treated as if it were virgin loading through taking the stress reversal point as the new generalized homological center of the bounding surface. Therefore, a new simple bounding-surface plasticity model with three important features for the cyclic behaviors of saturated clay is developed. Firstly, according to the movement of the generalized homological center, the model can harden not only isotropically but also kinematically to account for the anisotropy and memory the particular loading events. Secondly, the continuous cyclic loading is divided into the first loading, unloading and reloading processes and they are treated differently when calculating the hardening modulus to describe the soil responses accurately. The third feature is taking the generalized homological center as the mapping origin in the mapping rule to reflect the plastic flow in the unloading event. The behaviors of saturated clay for the monotonic and cyclic stress-controlled and strain-controlled triaxial tests are simulated by the model. The prediction results show an encouraging agreement with the experimental data.

  11. Cyclic Degradation Behavior of < 001 \\rangle -Oriented Fe-Mn-Al-Ni Single Crystals in Tension

    Science.gov (United States)

    Vollmer, M.; Kriegel, M. J.; Krooß, P.; Martin, S.; Klemm, V.; Weidner, A.; Chumlyakov, Y.; Biermann, H.; Rafaja, D.; Niendorf, T.

    2017-08-01

    In the present study, functional fatigue behavior of a near 〈001〉-oriented Fe-Mn-Al-Ni single crystal was investigated under tensile load. An incremental strain test up to 3.5% strain and cyclic tests up to 25 cycles revealed rapid pseudoelastic degradation. Progressive microstructural degradation was studied by in situ scanning electron microscopy. The results show a partially inhibited reactivation of previously formed martensite and proceeding activation of untransformed areas in subsequent cycles. The preferentially formed martensite variants were identified by means of Schmid factor calculation and the Kurdjumov-Sachs relationship. Post mortem transmission electron microscopy investigations shed light on the prevailing degradation mechanisms. Different types of dislocations were found promoting the progressive degradation during cyclic loading.

  12. Cyclic Voltammetry and Impedance Spectroscopy Behavior Studies of Polyterthiophene Modified Electrode

    Directory of Open Access Journals (Sweden)

    Naima Maouche

    2011-01-01

    Full Text Available We present in this work a study of the electrochemical behaviour of terthiophene and its corresponding polymer, which is obtained electrochemically as a film by cyclic voltammetry (CV on platinum electrode. The analysis focuses essentially on the effect of two solvents acetonitrile and dichloromethane on the electrochemical behaviour of the obtained polymer. The electrochemical behavior of this material was investigated by cyclic voltammetry and electrochemical impedance spectroscopy (EIS. The voltammograms show that the film of polyterthiophene can oxide and reduce in two solutions; in acetonitrile, the oxidation current intensity is more important than in dichloromethane. The impedance plots show the semicircle which is characteristic of charge-transfer resistance at the electrode/polymer interface at high frequency and the diffusion process at low frequency.

  13. A Model of Cyclic Transcriptomic Behavior in Cyanobacterium Cyanothece sp. ATCC 51142

    Energy Technology Data Exchange (ETDEWEB)

    McDermott, Jason E.; Oehmen, Christopher S.; McCue, Lee Ann; Hill, Eric A.; Choi, Daniel M.; Stockel, Jana; Liberton, Michelle L.; Pakrasi, Himadri B.; Sherman, Louis A.

    2011-07-01

    Systems biology attempts to reconcile large amounts of disparate data with existing knowledge to provide models of functioning biological systems. Useful and predictive models aim to summarize complex and dynamic processes and represent the relationships between these processes. The cyanobacterial Cyanothece species Strain sp. ATCC 51142 is an excellent candidate for such systems studies because: (i) it displays tight functional regulation as it must separate the opposing processes of oxygen-generating photosynthesis and oxygen-sensitive nitrogen fixation temporally in the same cell, ; (ii) it has robust cyclic patterns at the genetic, protein and metabolomic levels, ; and (iii) and it has potential applications for bioenergy and carbon sequestration, and thus a predictive model of its function is of practical use. We have represented the transcriptomic data from Cyanothece 51142 under diurnal light/dark cycles as a high-level functional abstraction and describe development of a predictive in silico model of diurnal and circadian behavior in terms of regulatory and metabolic processes in Cyanothece 51142. Our model provides a way to integrate disparate data types into a framework that can be used to explain behavior, generate high-quality predictions for validation, and to suggest future experiments. We show that incorporating network topology into the model improves performance in terms of our ability to explain the behavior of the system under new conditions. The model presented robustly describes transcriptomic behavior of Cyanothece 51142 under different cyclic and non-cyclic growth conditions robustly, and represents a significant advance in the understanding of gene regulation in this important organism.

  14. Cyclic Deformation Behavior and Fatigue Crack Propagation of Low Carbon Steel Prestrained in Tension

    Directory of Open Access Journals (Sweden)

    J. G. Wang

    2009-01-01

    Full Text Available The tests were performed on low carbon steel plate. In the tension fatigue tests, two angle values (ϕ=0° and ϕ=45°, ϕ is the angle between the loading and the rolling direction have been chosen. The influence of strain path change on the subsequent initial work softening rate and the saturation stress has been investigated. Dislocation microstructure was observed by transmission electron microscopy. It was found that the strain amount of preloading in tension has obviously affected the cyclic softening phenomenon and the initial cyclic softening rate. It was observed that the reloading axial stress for ϕ=45° case increased more than that of ϕ=0° case, due to the anisotropism of Q235. In the fatigue crack propagation tests, the experimental results show that with increasing the pretension deformation degree, the fatigue crack growth rate increases, especially at the near threshold section.

  15. The cyclic fatigue behavior of a Nicalon/SiC composite

    Energy Technology Data Exchange (ETDEWEB)

    Miriyala, N.; Liaw, P.K.; McHargue, C.J. [Univ. of Tennessee, Knoxville, TN (United States); Snead, L.L. [Oak Ridge National Lab., TN (United States)

    1996-10-01

    Cyclic fatigue tests were performed at ambient temperature on a Nicalon/SiC composite to study the effects of fabric orientation on the mechanical behavior. Four-point bend specimens were loaded either parallel or normal to the braided fabric plies. The maximum stresses chosen during the fatigue tests were 60, 70, and 80% of the monotonic strengths, respectively, in both orientations. Specimen failure did not occur in any case even after one million loading cycles. However, it was observed that much of the decrease in the composite modulus occurred in the first few (<10) cycles, and the fabric orientation did not significantly affect the effective modulus or midspan deflection trends.

  16. Behavior of Pile Group with Elevated Cap Subjected to Cyclic Lateral Loads

    Institute of Scientific and Technical Information of China (English)

    陈云敏; 顾明; 陈仁朋; 孔令刚; 张浙杭; 边学成

    2015-01-01

    The pile group with elevated cap is widely used as foundation of offshore structures such as turbines, power transmission towers and bridge piers, and understanding its behavior under cyclic lateral loads induced by waves, tide water and winds, is of great importance to designing. A large-scale model test on 3×3 pile group with elevated cap subjected to cyclic lateral loads was performed in saturated silts. The preparation and implementation of the test is presented. Steel pipes with the outer diameter of 114 mm, thickness of 4.5 mm, and length of 6 m were employed as model piles. The pile group was cyclic loaded in a multi-stage sequence with the lateral displacement controlled. In addition, a single pile test was also conducted at the same site for comparison. The displacement of the pile cap, the internal forces of individual piles, and the horizontal stiffness of the pile group are presented and discussed in detail. The results indicate that the lateral cyclic loads have a greater impact on pile group than that on a single pile, and give rise to the significant plastic strain in the soil around piles. The lateral loads carried by each row of piles within the group would be redistributed with loading cycles. The lateral stiffness of the pile group decreases gradually with cycles and broadly presents three different degradation patterns in the test. Significant axial forces were measured out in some piles within the group, owing to the strong restraint provided by the cap, and finally lead to a large settlement of the pile group. These findings can be referred for foundation designing of offshore structures.

  17. Behavior of pile group with elevated cap subjected to cyclic lateral loads

    Science.gov (United States)

    Chen, Yun-min; Gu, Ming; Chen, Ren-peng; Kong, Ling-gang; Zhang, Zhe-hang; Bian, Xue-cheng

    2015-06-01

    The pile group with elevated cap is widely used as foundation of offshore structures such as turbines, power transmission towers and bridge piers, and understanding its behavior under cyclic lateral loads induced by waves, tide water and winds, is of great importance to designing. A large-scale model test on 3×3 pile group with elevated cap subjected to cyclic lateral loads was performed in saturated silts. The preparation and implementation of the test is presented. Steel pipes with the outer diameter of 114 mm, thickness of 4.5 mm, and length of 6 m were employed as model piles. The pile group was cyclic loaded in a multi-stage sequence with the lateral displacement controlled. In addition, a single pile test was also conducted at the same site for comparison. The displacement of the pile cap, the internal forces of individual piles, and the horizontal stiffness of the pile group are presented and discussed in detail. The results indicate that the lateral cyclic loads have a greater impact on pile group than that on a single pile, and give rise to the significant plastic strain in the soil around piles. The lateral loads carried by each row of piles within the group would be redistributed with loading cycles. The lateral stiffness of the pile group decreases gradually with cycles and broadly presents three different degradation patterns in the test. Significant axial forces were measured out in some piles within the group, owing to the strong restraint provided by the cap, and finally lead to a large settlement of the pile group. These findings can be referred for foundation designing of offshore structures.

  18. Cyclic compressive creep-elastoplastic behaviors of in situ TiB{sub 2}/Al-reinforced composite

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Qing [School of Mechanical Engineering, Beijing Institute of Technology, 100081 (China); Zhang, Weizheng, E-mail: zhangwz@bit.edu.cn [School of Mechanical Engineering, Beijing Institute of Technology, 100081 (China); Liu, Youyi [School of Mechanical Engineering, State University of New York at Stony Brook, NY 11790 (United States); Guo, BingBin [School of Mechanical Engineering, Beijing Institute of Technology, 100081 (China)

    2016-06-01

    This paper presents a study on the cyclic compressive creep-elastoplastic behaviors of a TiB{sub 2}-reinforced aluminum matrix composite (ZL109) at 350 °C and 200 °C. According to the experimental results, under cyclic elastoplasticity and cyclic coupled compressive creep-elastoplasticity, the coupled creep will cause changes in isotropic stress and kinematic stress. Isotropic stress decreases with coupled creep, leading to cyclic softening. Positive kinematic stress, however, increases with coupled creep, leading to cyclic hardening. Transmission electron microscopy (TEM) observations of samples under cyclic compressive creep-elastoplasticity with different temperatures and strain amplitudes indicate that more coupled creep contributes to more subgrain boundaries but fewer intracrystalline dislocations. Based on the macro tests and micro observations, the micro mechanism of compressive creep's influence on cyclic elastoplasticity is elucidated. Dislocations recovering with coupled creep leads to isotropic softening, whereas subgrain structures created by coupled creep lead to kinematic hardening during cyclic deformation.

  19. MODELING OF NONLINEAR CYCLIC LOAD BEHAVIOR OF I-SHAPED COMPOSITE STEEL-CONCRETE SHEAR WALLS OF NUCLEAR POWER PLANTS

    Directory of Open Access Journals (Sweden)

    AHMER ALI

    2013-02-01

    Full Text Available In recent years steel-concrete composite shear walls have been widely used in enormous high-rise buildings. Due to high strength and ductility, enhanced stiffness, stable cycle characteristics and large energy absorption, such walls can be adopted in the auxiliary building; surrounding the reactor containment structure of nuclear power plants to resist lateral forces induced by heavy winds and severe earthquakes. This paper demonstrates a set of nonlinear numerical studies on I-shaped composite steel-concrete shear walls of the nuclear power plants subjected to reverse cyclic loading. A three-dimensional finite element model is developed using ABAQUS by emphasizing on constitutive material modeling and element type to represent the real physical behavior of complex shear wall structures. The analysis escalates with parametric variation in steel thickness sandwiching the stipulated amount of concrete panels. Modeling details of structural components, contact conditions between steel and concrete, associated boundary conditions and constitutive relationships for the cyclic loading are explained. Later, the load versus displacement curves, peak load and ultimate strength values, hysteretic characteristics and deflection profiles are verified with experimental data. The convergence of the numerical outcomes has been discussed to conclude the remarks.

  20. Cyclic oxidation behavior of plasma surface chromising coating on titanium alloy Ti-6Al-4V

    Energy Technology Data Exchange (ETDEWEB)

    Wei Dongbo, E-mail: weidb1982@163.com [College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211100 (China); Zhang Pingze; Yao Zhengjun; Zhou Jintang; Wei Xiangfei; Zhou Peng [College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211100 (China)

    2012-11-15

    Highlights: Black-Right-Pointing-Pointer A chromising coating in gradient distribution was obtained on Ti-6Al-4V titanium alloy. Black-Right-Pointing-Pointer The cyclic oxidation behavior of chromising coating was studied at 650-850 Degree-Sign C. Black-Right-Pointing-Pointer The Ti-Cr mutual diffusion layer changed into the Ti(Cr, Al){sub 2} laves phase layer, which prevented the inward diffusion of oxygen. Black-Right-Pointing-Pointer A multi-layers structure of Cr{sub 2}O{sub 3}, TiO{sub 2} and Al{sub 2}O{sub 3} formed during oxidation. Black-Right-Pointing-Pointer Ti, Al diffused toward the oxide-gas interface, Cr diffused predominantly outward. - Abstract: The cyclic oxidation behavior of plasma surface chromising coating on titanium alloy (Ti-6Al-4V) was researched in air at 650 Degree-Sign C, 750 Degree-Sign C and 850 Degree-Sign C. A NiCrAlY coating was prepared by multi-arc ion plating as a comparison. The surface morphologies, microstructures and phases of both coatings before and after oxidation were investigated using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X-ray diffractometry (XRD). The results show that the chromising coating consisted of an outer layer of loose Cr deposition, an intermediate layer of compact Cr deposition and an inner Ti-Cr mutual diffusion layer. The multilayer oxide scales formed in the oxidation process, which has the better cyclic oxidation resistance compared with NiCrAlY thermal barrier coating. However, the brittleness of Ti(Cr, Al){sub 2} laves phase resulted in spallation of oxide scales at 750 Degree-Sign C and 850 Degree-Sign C.

  1. Monotonic and Cyclic Behavior of DIN 34CrNiMo6 Tempered Alloy Steel

    Directory of Open Access Journals (Sweden)

    Ricardo Branco

    2016-04-01

    Full Text Available This paper aims at studying the monotonic and cyclic plastic deformation behavior of DIN 34CrNiMo6 high strength steel. Monotonic and low-cycle fatigue tests are conducted in ambient air, at room temperature, using standard 8-mm diameter specimens. The former tests are carried out under position control with constant displacement rate. The latter are performed under fully-reversed strain-controlled conditions, using the single-step test method, with strain amplitudes lying between ±0.4% and ±2.0%. After the tests, the fracture surfaces are examined by scanning electron microscopy in order to characterize the surface morphologies and identify the main failure mechanisms. Regardless of the strain amplitude, a softening behavior was observed throughout the entire life. Total strain energy density, defined as the sum of both tensile elastic and plastic strain energies, was revealed to be an adequate fatigue damage parameter for short and long lives.

  2. The Mechanical Behavior Of A Nylon Seat Belt Exposed To Cyclical Loads: A Numerical Approach

    Directory of Open Access Journals (Sweden)

    Lucas Nogueira Assis,

    2015-09-01

    Full Text Available This work aims to study the mechanical behavior of a nylon seat belt when it is exposed to cyclical loads through the Finite Element Methods. This work used as base the brazilian regulamentoy standard ABNT NBR 7337:2011 to create the virtual model of the seat belt, with the following dimensions: 1.20mm thick, 48mm width and 250mm length. The next step was to import this CAD model to ANSYS 14.5 software, to create the correct material model for this case and apply the correct boundary conditions in order to analyze its behavior under a load that varies from 0 to 2000 N at a 10 Hz frequency. The final step was to analyze this numerical results that referring to this component under these conditions.

  3. Breaking the cycle: cognitive behavioral therapy and biofeedback training in a case of cyclic vomiting syndrome.

    Science.gov (United States)

    Slutsker, Barak; Konichezky, Andres; Gothelf, Doron

    2010-12-01

    The present article presents a case of cognitive behavioral therapy (CBT) along with heart rate variability (HRV) biofeedback training for the treatment of a medication unresponsive 13-year-old boy with cyclic vomiting syndrome (CVS). CVS is characterized by recurring stereotypic episodes of vomiting, interspersed with asymptomatic periods. Triggers for vomiting include anticipatory anxiety related to school examinations, family conflicts, and birthday parties as well as infectious diseases, and certain foods. Current treatment design addressed two pivotal etiological factors: autonomic dysregulation and anticipatory anxiety. Treatment outcome suggests that vomiting episodes may be successfully prevented by aiding the patient to identify and manage precipitant psychological stressors, to regulate HRV patterns, and gain a renewed sense of bodily control and self-efficacy. Further research is suggested using a controlled study with pre- and post-behavioral and stress measures to evaluate the effectiveness of CBT and biofeedback training compared to pharmacotherapy and placebo.

  4. Mechanical behaviors of multi-filament twist superconducting strand under tensile and cyclic loading

    Science.gov (United States)

    Wang, Xu; Li, Yingxu; Gao, Yuanwen

    2016-01-01

    The superconducting strand, serving as the basic unit cell of the cable-in-conduit-conductors (CICCs), is a typical multi-filament twist composite which is always subjected to a cyclic loading under the operating condition. Meanwhile, the superconducting material Nb3Sn in the strand is sensitive to strain frequently relating to the performance degradation of the superconductivity. Therefore, a comprehensive study on the mechanical behavior of the strand helps understanding the superconducting performance of the strained Nb3Sn strands. To address this issue, taking the LMI (internal tin) strand as an example, a three-dimensional structural finite element model, named as the Multi-filament twist model, of the strand with the real configuration of the LMI strand is built to study the influences of the plasticity of the component materials, the twist of the filament bundle, the initial thermal residual stress and the breakage and its evolution of the filaments on the mechanical behaviors of the strand. The effective properties of superconducting filament bundle with random filament breakage and its evolution versus strain are obtained based on the damage theory of fiber-reinforced composite materials proposed by Curtin and Zhou. From the calculation results of this model, we find that the occurrence of the hysteresis loop in the cyclic loading curve is determined by the reverse yielding of the elastic-plastic materials in the strand. Both the initial thermal residual stress in the strand and the pitch length of the filaments have significant impacts on the axial and hysteretic behaviors of the strand. The damage of the filaments also affects the axial mechanical behavior of the strand remarkably at large axial strain. The critical current of the strand is calculated by the scaling law with the results of the Multi-filament twist model. The predicted results of the Multi-filament twist model show an acceptable agreement with the experiment.

  5. Cyclic Deformation Behavior of a Rare-Earth Containing Extruded Magnesium Alloy: Effect of Heat Treatment

    Science.gov (United States)

    Mirza, F. A.; Chen, D. L.; Li, D. J.; Zeng, X. Q.

    2015-03-01

    The present study was aimed at evaluating strain-controlled cyclic deformation behavior of a rare-earth (RE) element containing Mg-10Gd-3Y-0.5Zr (GW103K) alloy in different states (as-extruded, peak-aged (T5), and solution-treated and peak-aged (T6)). The addition of RE elements led to an effective grain refinement and weak texture in the as-extruded alloy. While heat treatment resulted in a grain growth modestly in the T5 state and significantly in the T6 state, a high density of nano-sized and bamboo-leaf/plate-shaped β' (Mg7(Gd,Y)) precipitates was observed to distribute uniformly in the α-Mg matrix. The yield strength and ultimate tensile strength, as well as the maximum and minimum peak stresses during cyclic deformation in the T5 and T6 states were significantly higher than those in the as-extruded state. Unlike RE-free extruded Mg alloys, symmetrical hysteresis loops in tension and compression and cyclic stabilization were present in the GW103K alloy in different states. The fatigue life of this alloy in the three conditions, which could be well described by the Coffin-Manson law and Basquin's equation, was equivalent within the experimental scatter and was longer than that of RE-free extruded Mg alloys. This was predominantly attributed to the presence of the relatively weak texture and the suppression of twinning activities stemming from the fine grain sizes and especially RE-containing β' precipitates. Fatigue crack was observed to initiate from the specimen surface in all the three alloy states and the initiation site contained some cleavage-like facets after T6 heat treatment. Crack propagation was characterized mainly by the characteristic fatigue striations.

  6. A Critical Assessment of Cyclic Softening and Hardening Behavior in a Near- α Titanium Alloy During Thermomechanical Fatigue

    Science.gov (United States)

    Prasad, Kartik; Sarkar, Rajdeep; Rao, K. Bhanu Sankara; Sundararaman, M.

    2016-10-01

    Thermomechanical fatigue behavior of Ti-alloy Timetal 834 has been studied at two temperature intervals viz. 573 K to 723 K (300 °C to 450 °C) and 723 K to 873 K (450 °C to 600 °C) under mechanical strain-controlled cycling. Among the temperatures studied, the alloy exhibited initial cyclic softening followed by cyclic hardening at 723 K (450 °C) in the temperature interval of 573 K to 723 K (300 °C to 450 °C). However, continuous cyclic hardening was observed at 723 K (450 °C) in 723 K to 873 K (450 °C to 600 °C). At 573 K (300 °C) and 873 K (600 °C), cyclic softening was observed in the cyclic stress response curves in both the temperature intervals. The dislocation substructure was observed to be planar in both the modes of TMF loading. Based on TEM microstructures and few unconventional fatigue tests, the observed cyclic hardening is attributed to dynamic strain aging. The reduced fatigue life at 723 K to 873 K (450 °C to 600 °C) under OP-TMF loading was attributed to the combined effect of cyclic hardening (leading to early strain localization and crack initiation), oxidation, and development of tensile mean stresses.

  7. A Dynamic Gene Regulatory Network Model That Recovers the Cyclic Behavior of Arabidopsis thaliana Cell Cycle

    Science.gov (United States)

    Ortiz-Gutiérrez, Elizabeth; García-Cruz, Karla; Azpeitia, Eugenio; Castillo, Aaron; Sánchez, María de la Paz; Álvarez-Buylla, Elena R.

    2015-01-01

    Cell cycle control is fundamental in eukaryotic development. Several modeling efforts have been used to integrate the complex network of interacting molecular components involved in cell cycle dynamics. In this paper, we aimed at recovering the regulatory logic upstream of previously known components of cell cycle control, with the aim of understanding the mechanisms underlying the emergence of the cyclic behavior of such components. We focus on Arabidopsis thaliana, but given that many components of cell cycle regulation are conserved among eukaryotes, when experimental data for this system was not available, we considered experimental results from yeast and animal systems. We are proposing a Boolean gene regulatory network (GRN) that converges into only one robust limit cycle attractor that closely resembles the cyclic behavior of the key cell-cycle molecular components and other regulators considered here. We validate the model by comparing our in silico configurations with data from loss- and gain-of-function mutants, where the endocyclic behavior also was recovered. Additionally, we approximate a continuous model and recovered the temporal periodic expression profiles of the cell-cycle molecular components involved, thus suggesting that the single limit cycle attractor recovered with the Boolean model is not an artifact of its discrete and synchronous nature, but rather an emergent consequence of the inherent characteristics of the regulatory logic proposed here. This dynamical model, hence provides a novel theoretical framework to address cell cycle regulation in plants, and it can also be used to propose novel predictions regarding cell cycle regulation in other eukaryotes. PMID:26340681

  8. Cyclic behavior of sandy shoals on the ebb-tidal deltas of the Wadden Sea

    Science.gov (United States)

    Ridderinkhof, W.; Hoekstra, P.; van der Vegt, M.; de Swart, H. E.

    2016-03-01

    Ebb-tidal deltas are bulges of sand that are located seaward of tidal inlets. Many of these deltas feature shoals that cyclically form and migrate towards the coast. The average period between successive shoals that attach to the coast varies among different inlets. In this study, a quantitative assessment of the cyclic behavior of shoals on the ebb-tidal deltas of the Wadden Sea is presented. Analysis of bathymetric data and Landsat satellite images revealed that at the majority of inlets along the Wadden Sea migrating shoals occur. The average period between succeeding shoals correlates to the tidal prism and has values ranging between 4 and 130 years. A larger tidal prism favors larger periods between successive shoal attachments. However, such a relationship was not found for wide inlets with multiple channels. There is a positive relationship between the frequency with which the shoals attach to the coast and their migration velocity, and a negative relationship between the migration velocity of the shoal and the tidal prism. Finally, the data were too sparse to assess whether the longshore sediment transport has a significant effect on the period between successive shoals that attach to the coasts downdrift of the observed tidal inlets.

  9. Experimental Modeling of Pile-Leg Interaction in Jacket Type Offshore Platforms Cyclic Inelastic Behavior

    Directory of Open Access Journals (Sweden)

    M. R. Honarvar

    2008-01-01

    Full Text Available Offshore platforms in seismically active areas should be designed to survive in the event of severe ground excitations with no global structural failure. The annulus between the pile and leg in jacket-type offshore platforms can be filled with cement grout as a means of reducing horizontal deflections, inhibiting corrosion and preventing local damages. This paper discusses an experimental approach which can be used to demonstrate the effect of grouting on enhanced structural performance of jackets. In this regard, the lateral load bearing behavior of grouted and un-grouted jackets are investigated experimentally with special attention to effect of grout on pile-leg interaction. Results are presented on the cyclic inelastic behavior of two scaled frame models of a representative platform which was recently installed in the Persian gulf. The objective of this effort was to improve the understanding of the behavior of jackets subjected to lateral motions and specially the effects of exact real pile-leg interaction. it should be noted that this paper addresses the exact and realistic pile-leg interaction. It is concluded that grouting can not be considered as a definite method of improving strength and structural nonlinear dynamic behavior. Although it generally increases the lateral stiffness, but some side effects and points are to be considered. In this paper, the two separate lateral load bearing mechanisms -namely portal (braced mechanism and frame bending mechanism- are distinguished and the effect of grout on each one is shown.

  10. Long-term behavior of a cyclic max-type system of difference equations

    Directory of Open Access Journals (Sweden)

    Tatjana Stevic

    2015-09-01

    Full Text Available We study the long-term behavior of positive solutions of the cyclic system of difference equations $$ x^{(i}_{n+1}=\\max\\Big\\{\\alpha,\\frac{(x^{(i+1}_n^p}{(x^{(i+2}_{n-1}^q}\\Big\\}, \\quad i=1,\\ldots,k,\\; n\\in\\mathbb{N}_0, $$ where $k\\in\\mathbb{N}$, $\\min\\{\\alpha, p, q\\}>0$ and where we regard that $x^{(i_1}_n=x^{(i_2}_n$ when $i_1\\equiv i_2$ (mod $k$. We determine the set of parameters $\\alpha$, p and q in $(0,\\infty^3$ for which all such solutions are bounded. In the other cases we show that the system has unbounded solutions. For the case p=q we give some sufficient conditions which guaranty the convergence of all positive solutions. The main results in this paper generalize and complement some recent ones.

  11. Influences of Yttrium on Cyclic Oxidation Behavior of Fe-Cr-Al Alloy

    Institute of Scientific and Technical Information of China (English)

    辛丽; 李美栓; 钱余海; 李铁藩

    2001-01-01

    The 1100 ℃ cyclic oxidation behavior of Fe-23Cr-5Al alloy modified by yttrium was studied. Yttrium was added to this alloy in the form of (1) metallic addition, (2) yttrium oxide dispersion and (3) ion implantation. Cracking and spalling occurred on the convoluted scale formed on Y-free alloy and the substrate was exposed. A flat dense scale without spallation was formed on the yttrium alloying addition or yttrium oxide dispersion alloy. Spallation mainly occurred between two layers of the scale on the 1×1017Y ions/cm2-implanted alloy. The results indicate the main reason that the adhesion of alumina scale was improved by yttrium addition lies in that yttrium is liable to form a stable yttrium sulfide with sulfur in the alloy and prevent sulfur interface segregation. Another reason is that the growth mechanism of alumina scale was changed by yttrium addition.

  12. A coupled damage-plasticity model for the cyclic behavior of shear-loaded interfaces

    Science.gov (United States)

    Carrara, P.; De Lorenzis, L.

    2015-12-01

    The present work proposes a novel thermodynamically consistent model for the behavior of interfaces under shear (i.e. mode-II) cyclic loading conditions. The interface behavior is defined coupling damage and plasticity. The admissible states' domain is formulated restricting the tangential interface stress to non-negative values, which makes the model suitable e.g. for interfaces with thin adherends. Linear softening is assumed so as to reproduce, under monotonic conditions, a bilinear mode-II interface law. Two damage variables govern respectively the loss of strength and of stiffness of the interface. The proposed model needs the evaluation of only four independent parameters, i.e. three defining the monotonic mode-II interface law, and one ruling the fatigue behavior. This limited number of parameters and their clear physical meaning facilitate experimental calibration. Model predictions are compared with experimental results on fiber reinforced polymer sheets externally bonded to concrete involving different load histories, and an excellent agreement is obtained.

  13. Thermomechanical behavior of different Ni-base superalloys during cyclic loading at elevated temperatures

    Directory of Open Access Journals (Sweden)

    Huber Daniel

    2014-01-01

    Full Text Available The material behavior of three Ni-base superalloys (Inconel® 718, Allvac® 718PlusTM and Haynes® 282® during in-phase cyclic mechanical and thermal loading was investigated. Stress controlled thermo-mechanical tests were carried out at temperatures above 700 ∘C and different levels of maximum compressive stress using a Gleeble® 3800 testing system. Microstructure investigations via light optical microscopy (LOM and field emission gun scanning electron microscopy (FEG-SEM as well as numerical precipitation kinetics simulations were performed to interpret the obtained results. For all alloys, the predominant deformation mechanism during deformation up to low plastic strains was identified as dislocation creep. The main softening mechanism causing progressive increase of plastic strain after preceding linear behavior is suggested to be recrystallization facilitated by coarsening of grain boundary precipitates. Furthermore, coarsening and partial transformation of strengthening phases was observed. At all stress levels, Haynes® 282® showed best performance which is attributable to its stable microstructure containing a high phase fraction of small, intermetallic precipitates inside grains and different carbides evenly distributed along grain boundaries.

  14. [Involvement of cyclic adenosine monophosphate in the control of motile behavior of Physarum polycephalum plasmodium].

    Science.gov (United States)

    Matveeva, N B; Teplov, V A; Nezvetskiĭ, A R; Orlova, T G; Beĭlina, S I

    2012-01-01

    Possible involvement of autocrine factors into the control of motile behavior via a receptor-mediated mechanism was investigated in Physarum polycephalum plasmodium, a multinuclear amoeboid cell with the auto-oscillatory mode of motility. Cyclic adenosine monophosphate (cAMP) and extracellular cAMP-specific phosphodiesterase, its involvement into the control of plasmodium motile behavior was proved by action of its strong inhibitor, were regarded as putative autocrine factors. It was shown that the plasmodium secreted cAMP. When it was introduced into agar support, 0,1-1 mM cAMP induced a delay of the plasmodium spreading and its transition to migration. When locally applied, cAMP at the same concentrations induced typical for attractant action the increase in oscillation frequency and the decrease of ectoplasm elasticity. The ability to exhibit positive chemotaxis in cAMP gradient and the dependence of its realization were shown to depend on the plasmodium state. Chemotaxis test specimens obtained from the migrating plasmodium, unlike those obtained from growing culture, generate alternative fronts which compete effectively with fronts oriented towards the attractant increment. The results obtained support our supposition stated earlier that advance of the Physarum polycephalum plasmodium leading edge is determined by local extracellular cAMP gradients arising from a time delay between secretion and hydrolysis of the nucleotide.

  15. Influence of Nickel Particle Reinforcement on Cyclic Fatigue and Final Fracture Behavior of a Magnesium Alloy Composite

    Directory of Open Access Journals (Sweden)

    Manoj Gupta

    2012-06-01

    Full Text Available The microstructure, tensile properties, cyclic stress amplitude fatigue response and final fracture behavior of a magnesium alloy, denoted as AZ31, discontinuously reinforced with nano-particulates of aluminum oxide and micron size nickel particles is presented and discussed. The tensile properties, high cycle fatigue and final fracture behavior of the discontinuously reinforced magnesium alloy are compared with the unreinforced counterpart (AZ31. The elastic modulus and yield strength of the dual particle reinforced magnesium alloy is marginally higher than of the unreinforced counterpart. However, the tensile strength of the composite is lower than the monolithic counterpart. The ductility quantified by elongation to failure over 0.5 inch (12.7 mm gage length of the test specimen showed minimal difference while the reduction in specimen cross-section area of the composite is higher than that of the monolithic counterpart. At the microscopic level, cyclic fatigue fractures of both the composite and the monolithic alloy clearly revealed features indicative of the occurrence of locally ductile and brittle mechanisms. Over the range of maximum stress and at two different load ratios the cyclic fatigue resistance of the magnesium alloy composite is superior to the monolithic counterpart. The mechanisms responsible for improved cyclic fatigue life and resultant fracture behavior of the composite microstructure are highlighted.

  16. Initial corrosion behavior of AZ91 magnesium alloy in simulating acid rain under wet-dry cyclic condition

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Corrosion behavior of AZ91 magnesium alloy in simulating acid rain under wet-dry cyclic condition was investigated.The results show that corrosion potential shifts positively and the corrosion current density decreases at low wet-dry cyclic time.Further increase of the cyclic time results in the negative movement of corrosion potential and the increase of current density.SEM observation indicates that corrosion Occurs only in αphase,βphase is inert in corrosive medium,and the corrosion of AZ91 magnesium appears in uniform characteristic.XPS analysis suggests that the corrosion product is mainly composed of oxide and hydroxide of magnesium and aluminum,and a small amount of sulfate is also contained in the film.

  17. Effect of dynamic monotonic and cyclic loading on fracture behavior for Japanese carbon steel pipe STS410

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, Kanji; Murayama, Kouichi; Ogata, Hiroyuki [and others

    1997-04-01

    The fracture behavior for Japanese carbon steel pipe STS410 was examined under dynamic monotonic and cyclic loading through a research program of International Piping Integrity Research Group (EPIRG-2), in order to evaluate the strength of pipe during the seismic event The tensile test and the fracture toughness test were conducted for base metal and TIG weld metal. Three base metal pipe specimens, 1,500mm in length and 6-inch diameter sch.120, were employed for a quasi-static monotonic, a dynamic monotonic and a dynamic cyclic loading pipe fracture tests. One weld joint pipe specimen was also employed for a dynamic cyclic loading test In the dynamic cyclic loading test, the displacement was controlled as applying the fully reversed load (R=-1). The pipe specimens with a circumferential through-wall crack were subjected four point bending load at 300C in air. Japanese STS410 carbon steel pipe material was found to have high toughness under dynamic loading condition through the CT fracture toughness test. As the results of pipe fracture tests, the maximum moment to pipe fracture under dynamic monotonic and cyclic loading condition, could be estimated by plastic collapse criterion and the effect of dynamic monotonic loading and cyclic loading was a little on the maximum moment to pipe fracture of the STS410 carbon steel pipe. The STS410 carbon steel pipe seemed to be less sensitive to dynamic and cyclic loading effects than the A106Gr.B carbon steel pipe evaluated in IPIRG-1 program.

  18. Fatigue behavior and cumulative damage rule of concrete under cyclic compression with constant confined stress

    Institute of Scientific and Technical Information of China (English)

    ZHU Jin-song; GAO Chang-e; SONG Yu-pu

    2005-01-01

    The effects of different lateral confinement stress on the fatigue behavior and cumulative damage of plain concrete were investigated experimentally. Eighty 100mm × 100mm × 100mm specimens of ordinary strength concrete were tested with constant-or variable-amplitude cyclic compression and lateral confinement pressure in two orthogonal directions. A fatigue equation was gained by modifying the classical Aas-Jakobsen SN equation and used for taking into account the effect of the confined stress on fatigue strength of plain concrete. The present study indicates that the fatigue failure is greatly influenced by the sequence of applied variable-amplitude fatigue loading, and Miner's rule is inapplicable to predict the residual fatigue life, especially in the sequence of low to high. The present research also shows that the exponent d of the Corten-Dolan's damage formula is a constant depending on the materials and the levels of load spectrum, and d can be determined through the two-stage fatigue tests. The residual fatigue lives predicted by Corten-Dolan' s damage formula are found to be in good agreement with the results of the experiments.

  19. The cyclic oxidation behavior of the single crystal TMS-82+ superalloy in humidified air

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Y. [School of Materials Science and Engineering, Shanghai, Institute of Technology, Shanghai (China); Research Group of Interface Control Engineering, Graduate School of Engineering, Hokkaido University, Sapporo (Japan); Narita, T. [Research Group of Interface Control Engineering, Graduate School of Engineering, Hokkaido University, Sapporo (Japan)

    2009-10-15

    The cyclic oxidation behavior of a single crystal Ni-based superalloy TMS-82+ was studied at 800 and 900 C for 200 h in water vapor (air plus 15% H{sub 2}O). Regardless of the exposure temperature, time-dependence of the growth rate of the scale for the superalloy was fitted by a subparabolic relationship. The oxidation rate was enhanced with increase in exposure temperature, which was evidenced by a higher mass gain and thicker scale. The oxides on the specimen at 800 C consisted of (Ni,Co)O, CrTaO{sub 4}, AlTaO{sub 4}, Cr{sub 2}O{sub 3}, and {theta}-Al{sub 2}O{sub 3}, whereas for the specimen exposed at 900 C, spinels of NiCr{sub 2}O{sub 4} and (Ni,Co)Al{sub 2}O{sub 4} as well as {alpha}-Al{sub 2}O{sub 3} were observed. An innermost dense {alpha}-Al{sub 2}O{sub 3} layer was responsible for a stable growth rate of the scale after the initial rapid oxidation. (Abstract Copyright [2009], Wiley Periodicals, Inc.)

  20. Experimental research on behavior of 460 MPa high strength steel I-section columns under cyclic loading

    Science.gov (United States)

    Wang, Jiaojiao; Shi, Gang; Shi, Yongjiu

    2014-12-01

    To investigate the seismic behavior of I-section columns made of 460 MPa high strength steel (HSS), six specimens were tested under constant axial load and cyclic horizontal load. The specimens were designed with different width-to-thickness ratios and loaded under different axial load ratios. For each specimen, the failure mode was observed and hysteretic curve was measured. Comparison of different specimens on hysteretic characteristic, energy dissipation capacity and deformation capacity were further investigated. Test results showed that the degradation of bearing capacity was due to local buckling of flange and web. Under the same axial load ratio, as width-to-thickness ratio increased, the deformation area of local buckling became smaller. And also, displacement level at both peak load and failure load became smaller. In addition, the full extent of hysteretic curve, energy dissipation capacity, ultimate story drift angle decreased, and capacity degradation occurred more rapidly with the increase of width-to-thickness ratio or axial load ratio. Based on the capacity of story drift angle, limiting values which shall not be exceeded are suggested respectively for flange and web plate of 460 MPa HSS I-section columns when used in SMFs and in IMFs in the case of axial load ratio no more than 0.2. Such values should be smaller when the axial load ratio increases.

  1. Exploring the dynamic behaviors and transport properties of gas molecules in a transmembrane cyclic peptide nanotube.

    Science.gov (United States)

    Li, Rui; Fan, Jianfen; Li, Hui; Yan, Xiliang; Yu, Yi

    2013-12-05

    The dynamic behaviors and transport properties of O2, CO2, and NH3 molecules through a transmembrane cyclic peptide nanotube (CPNT) of 8×cyclo-(WL)4/POPE have been investigated by steered molecular dynamics (SMD) simulations and adaptive biasing force (ABF) samplings. Different external forces are needed for three gas molecules to enter the channel. The periodic change of the pulling force curve for a gas traveling through the channel mainly arises from the regular and periodic arrangement of the composed CP subunits of the CPNT. Radial distribution functions (RDFs) between gas and water disclose the density decrease of channel water, which strongly aggravates the discontinuity of H-bond formation between a gas molecule and the neighboring water. Compared to hardly any H-bond formation between CO2 (or O2) and the framework of the CPNT, NH3 can form abundant H-bonds with the carbonyl/amide groups of the CPNT, leading to a fierce competition to NH3-water H-bonded interactions. In addition to direct H-bonded interactions, all three gases can form water bridges with the tube. The potential profile of mean force coincides with the occurring probability of a gas molecule along the tube axis. The energy barriers at two mouths of the CPNT elucidate the phenomenon that CO2 and O2 are thoroughly confined in the narrow lumen while NH3 can easily go outside the tube. Intermolecular interactions of each gas with channel water and the CPNT framework and the formation of H-bonds and water bridges illuminate the different gas translocation behaviors. The results uncover interesting and comprehensive mechanisms underlying the permeation characteristics of three gas molecules traveling through a transmembrane CPNT.

  2. Cyclic delamination behavior of plasma-sprayed hydroxyapatite coating on Ti-6Al-4V substrates in simulated body fluid.

    Science.gov (United States)

    Otsuka, Yuichi; Kawaguchi, Hayato; Mutoh, Yoshiharu

    2016-10-01

    This study aimed to clarify the effect of a simulated body fluid (SBF) on the cyclic delamination behavior of a plasma-sprayed hydroxapatite (HAp) coating. A HAp coating is deposited on the surfaces of surgical metallic materials in order to enhance the bond between human bone and such surfaces. However, the HAp coating is susceptible to delamination by cyclic loading from the patient's gait. Although hip joints are subjected to both positive and negative moments, only the effects of tensile bending stresses on vertical crack propagation behavior have been investigated. Thus, the cyclic delamination behavior of a HAp coating was observed at the stress ratio R=-1 in order to determine the effects of tensile/compressive loading on the delamination behavior. The delamination growth rate increased with SBF immersion, which decreased the delamination life. Raman spectroscopy analysis revealed that the selective phase dissolution in the HAp coating was promoted at interfaces. Finite element analysis revealed that the energy release rate Gmax showed a positive value even in cases with compressive loading, which is a driving force for the delamination of a HAp coating. A prediction model for the delamination growth life was developed that combines a fracture mechanics parameter with the assumed stress-dependent dissolution rate. The predicted delamination life matched the experimental data well in cases of lower stress amplitudes with SBF. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Behavior of equipment. Project of cyclic stimulation with hot water. [Venezuela

    Energy Technology Data Exchange (ETDEWEB)

    Socorro, J.B.; Reid, T.B.

    1972-01-01

    This paper presents the results of the project of cyclic hot water injection carried out in the Morichal field, Monagas State, Venezuela, by Phillips Petroleum Co. A total of 66 billion btu of heat was injected in 21 wells for a total increment of 560,000 bbl in petroleum production. This increment in the production of petroleum was due to 2 reasons: (1) the cleanness of the formation around the wells, of the tube's perforations, and of the gravel packing caused by the removal of asphalt deposits, carbonates, etc.; and (2) reduction of the viscosity of petroleum caused by the increase of the temperature. The best results were obtained from wells in which production had decreased from plugging of flow channels in the surrounding formation, wells in good mechanical conditions and wells which were adjacent to undeveloped areas. The experience of this project points out that: (1) during a second cycle of stimulation, a production increment is obtained of approx. 80% as compared to that of the first cycle; (2) at least 2 billion btu of heat has to be injected per cycle; and (3) the wells that have a bad response to a cycle of stimulation should not be stimulated again unless the cause of bad response is eliminated or corrected.

  4. Corrosion Behavior of S450EW Low-alloy Weathering Steel in Cyclically Alternate Corrosion Environments

    Institute of Scientific and Technical Information of China (English)

    Jun-shan WANG; Pei-yang SHI; Cheng-jun LIU; Mao-fa JIANG

    2015-01-01

    Weathering steel is widely used in various ifelds due to its excellent mechanical properties and high corrosion resistance. The effect of chromium content on the S450EW weathering steel in cyclic immersion test was studied. The results indicated that the corrosion resistance of S450EW weathering steel is closely related to chromium content. The addition of chromium signiif-cantly inhibited the weathering steel corrosion. The corrosion rate of experimental steel after 96 h immersion was 1.101 g·m−2·h−1. The rust of S450EW weathering steel was mainly constituted of FeOOH and Fe3O4 phase, and the elevation of chromium content promoted the formation of α-FeOOH. The ifne precipitates of the two phases contributed to the formation of dense dust layer of test steel. Furthermore, the increase of chromium is beneifcial for the cure of original defects and cracks of the rust layer via the enrich-ment of chromium. The corrosion potential and the resistance of corrosion process were thus increased, protecting the experimental steel from further corrosion. A S450EW steel with corrosion resistance more than 1.5 times of Q450NQR1 steel was prepared.

  5. Effect of cyclic outer and inner bending on the fatigue behavior of a multi-layer metal film on a polymer substrate

    Science.gov (United States)

    Kim, Byoung-Joon; Shin, Hae-A.-Seul; Lee, Ji-Hoon; Joo, Young-Chang

    2016-06-01

    The electrical reliability of a multi-layer metal film on a polymer substrate during cyclic inner bending and outer bending is investigated using a bending fatigue system. The electrical resistance of a Cu film on a polymer substrate during cyclic outer bending increases due to fatigue damage formation, such as cracks and extrusion. Cyclic inner bending also leads to fatigue damage and a similar increase in the electrical resistance. In a sample having a NiCr under-layer, however, the electrical resistance increases significantly during outer bending but not during inner bending mode. Cross-sectional observations reveal that brittle cracking in the hard under-layer results in different fatigue behaviors according to the stress mode. By applying an Al over-layer, the fatigue resistance is improved during both outer bending and inner bending by suppressing fatigue damage formation. The effects of the position, materials, and thickness of the inter-layer on the electrical reliability of a multi-layer sample are also investigated. This study can provide meaningful information for designing a multi-layer structure under various mechanical deformations including tensile and compressive stress.

  6. [Analysis of sick leaves due to mental and behavioral problems].

    Science.gov (United States)

    Miranda, Gonzalo H; Alvarado, Sergio O; Kaufman, Jay S

    2012-02-01

    In Chile, the number of sick leaves due to mental health problems has systematically increased in recent years. To perform an analysis of sick leaves due to mental problems managed by the Fondo Nacional de Salud (FONASA) during 2008. Analysis of all sick leaves awarded during 2008 for mental or behavioral problems, that were managed at FONASA. A negative binomial regression, was performed to predict the effects of different variables on the total duration of sick leaves. A total of 546,477 sick leaves were awarded to 198,752 individuals (2.27 per subject). The mean duration of each leave was 15.6 days. Summing all leaves, the lapse off work was 98 ± 96 days (median 65 days). Women had longer leaves than men. The type of medical leave, occupation, working for private or public institutions, economic activity and diagnosis were significantly associated with duration of time off work. Sick leaves for mental problems are prolonged and related to gender and socioeconomic variables.

  7. Cyclic stress-strain behavior of polymeric nonwoven structures for the use as artificial leaflet material for transcatheter heart valve prostheses

    Directory of Open Access Journals (Sweden)

    Arbeiter Daniela

    2017-09-01

    Full Text Available Xenogenic leaflet material, bovine and porcine pericardium, is widely used for the fabrication of surgically implanted and transcatheter heart valve prostheses. As a biological material, long term durability of pericardium is limited due to calcification, degeneration and homogeneity. Therefore, polymeric materials represent a promising approach for a next generation of artificial heart valve leaflets with improved durability. Within the current study we analyzed the mechanical performance of polymeric structures based on elastomeric materials. Polymeric cast films were prepared and nonwovens were manufactured in an electrospinning process. Analysis of cyclic stress-strain behavior was performed, using a universal testing machine. The uniaxial cyclic tensile experiments of the elastomeric samples yielded a non-linear elastic response due to viscoelastic behavior with hysteresis. Equilibrium of stress-strain curves was found after a specific number of cycles, for cast films and nonwovens, respectively. In conclusion, preconditioning was found obligatory for the evaluation of the mechanical performance of polymeric materials for the use as artificial leaflet material for heart valve prostheses.

  8. A cyclic behavior of CME accelerations for accelerating and decelerating events

    Institute of Scientific and Technical Information of China (English)

    Peng-Xin Gao; Ke-Jun Li

    2009-01-01

    We investigate the cyclic evolutionary behavior of CME accelerations for accelerating and decelerating CME events in cycle 23 from 1997 January to 2007 December.It is found that the absolute values of semiannual mean accelerations of both accelerating and decelerating CME events roughly wax and wane in a cycle,delaying the sunspot cycle in time phase.We also investigate the semiannual number of CMEs with positive and negative acceleration and find that there are more decelerating CME events than accelerating CME events during the maximum period of a cycle (about three years),but there are more accelerating CME events than decelerating CME events during the rest of the time interval of the cycle.Our results seem to suggest that the different driving mechanisms may be acting accelerate and decelerate CME events: for accelerating CME events,the propelling force (Fp) statistically seems to play a significant role in pushing CMEs outward;for decelerating CME events,the drag (F_d) statistically seems to play a more effective role in determining CME kinematic evolution in the outer corona.During the maximum period of a cycle,because of the V_2 dependence,Fd is generally stronger; because of the magnetic field dependence,Fp is also generally stronger.Thus,the absolute values of both the negative and positive accelerations are generally larger during that time.Because of the V2 dependence,Fd may be more effective during the maximum period of a cycle.Hence,there are more decelerating CME events than accelerating CME events during that time.During the minimum time interval of a cycle,CMEs have relatively small speeds,and Fp may be more effective.Therefore,there are more accelerating CME events than decelerating CME events during that time.

  9. Changes in cyclic nucleotides, locomotory behavior, and body length produced by novel endogenous neuropeptides in the parasitic nematode Ascaris suum.

    Science.gov (United States)

    Reinitz, Catharine A; Pleva, Anthony E; Stretton, Antony O W

    2011-11-01

    Recent technical advances have rapidly advanced the discovery of novel peptides, as well as the transcripts that encode them, in the parasitic nematode Ascaris suum. Here we report that many of these novel peptides produce profound and varied effects on locomotory behavior and levels of cyclic nucleotides in A. suum. We investigated the effects of 31 endogenous neuropeptides encoded by transcripts afp-1, afp-2, afp-4, afp-6, afp-7, and afp-9-14 (afp: Ascaris FMRFamide-like Precursor protein) on cyclic nucleotide levels, body length and locomotory behavior. Worms were induced to generate anteriorly propagating waveforms, peptides were injected into the pseudocoelomic cavity, and changes in the specific activity (nmol/mg protein) of second messengers cAMP (3'5' cyclic adenosine monophosphate) and cGMP (3'5' cyclic guanosine monophosphate) were determined. Many of these neuropeptides changed the levels of cAMP (both increases and decreases were found), whereas few neuropeptides changed the level of cGMP. A subset of the peptides that lowered cAMP was investigated for effects on the locomotory waveform and on body length. Injection of AF19, or AF34 (afp-13), AF9 (afp-14), AF26 or AF41 (afp-11) caused immediate paralysis and cessation of propagating body waveforms. These neuropeptides also significantly increased body length. In contrast, injection of AF15 (afp-9) reduced the body length, and decreased the amplitude of waves in the body waveform. AF30 (afp-10) produced worms with tight ventral coils. Although injection of neuropeptides encoded by afp-1 (AF3, AF4, AF10 or AF13) produced an increased number of exaggerated body waves, there were no effects on either cAMP or cGMP. By injecting peptides into behaving A. suum, we have provided an initial screen of the effects of novel peptides on several behavioral and biochemical parameters.

  10. PSI showed higher tolerance to Sb(V) than PSII due to stimulation of cyclic electron flow around PSI.

    Science.gov (United States)

    Wang, Shuzhi; Pan, Xiangliang; Zhang, Daoyong

    2015-01-01

    The knowledge of the effects of Sb(V) on the physiological characteristics of cyanobacteria was still limited. In the present study, responses of photosystem I and II (PSI and PSII), cyclic electron flow (CEF), and interphotosystem electron transport of Microcystis aeruginosa to 5-100 mg/l Sb(V) were synchronously measured using the Dual-PAM-100. 5 mg/l Sb (V) significantly inhibited PSII activity, but had no significant effects on PSI activity. At higher concentrations of Sb(V), the quantum yield and electron transport of PSI were less affected compared to PSII. The ratio of Y(II)/Y(I) significantly decreased with increasing Sb(V) concentration. It decreased from 0.7 for control to 0.4 for 100 mg/l Sb(V)-treated cells, indicating that the change of the distribution of quantum yields between two photosystems and more serious inhibition of PSII under stress of Sb(V) compared to PSI. CEF was activated associated with the inhibition of linear electron flow after exposure to Sb(V). The contribution of Y(CEF) to the quantum yield and activity of PSI increased with increasing Sb(V) concentrations. The cyclic electron transport rate made a significant contribution to electron transport rate of PSI, especially at high Sb(V) concentration (100 mg/l) and high illumination (above 555 μmol photons/m(2)/s). The stimulation of CEF was essential for the higher tolerance of PSI than PSII to Sb(V).

  11. Multiaxial fatigue behavior of conventional and highly crosslinked UHMWPE during cyclic small punch testing.

    Science.gov (United States)

    Villarraga, M L; Kurtz, S M; Herr, M P; Edidin, A A

    2003-08-01

    Previous observations of reduced uniaxial elongation, fracture resistance, and crack propagation resistance of highly crosslinked ultrahigh molecular weight polyethylene (UHMWPE) have contributed to concern that the technology may not be appropriate for systems undergoing cyclic fatigue loading. Using a "total life" approach, we examined the influence of radiation crosslinking on the fatigue response of UHMWPE under cyclic loading via the small punch test. Our goal in this study was to evaluate the suitability of the small punch test for conducting miniature-specimen, cyclic loading, and fatigue experiments of conventional and highly crosslinked UHMWPE. We subjected four types of conventional and highly crosslinked UHMWPE to cyclic loading at 200 N/s and at body temperature in a small punch test apparatus. After failure, the fracture surfaces were characterized with the use of field emission scanning electron microscopy to evaluate the fatigue mechanisms. Cyclic small punch testing under load control was found to be an effective and repeatable method for relative assessment of the fatigue resistance of conventional and highly crosslinked UHMWPE specimens under multiaxial loading conditions. For each of the four conventional and highly crosslinked UHMWPE materials evaluated in this study, fatigue failures were consistently produced according to a power law relationship in the low cycle regimen, corresponding to failures below 10000 cycles. The fatigue failures were all found to be consistent with a single source of initiation and propagation to failure. Our long-term goal in this research is to develop miniature-specimen fatigue testing techniques for characterization of retrieved UHMWPE inserts.

  12. Si-Al COATING ON PURE MOLYBDENUM SUBSTRATE AND ITS CYCLIC OXIDATION BEHAVIOR

    Institute of Scientific and Technical Information of China (English)

    F.S.Liu; J.L.Xu; C.G.Zhou; S.K.Gong; H.B.Xu

    2004-01-01

    The halide-activated pack cementation method is utilized to codeposit aluminum and silicon on Mo substrate. Emphasis is placed on the microstructure and elevated-temperature oxidation resistance of coatings. The results show that hexagonal Mo (Si, Al)2 as a main phase and a little amount of the lower disilicide MosSis was formed on Mo substrate through the halide-activated pack cementation method. The resultant Si-Al coating on Mo substrate exhibits excellent cyclic oxidation resistance. The excellent cyclic oxidation resistance of the coatings is attributed to the formation of alumina on the coatings during the oxidation.

  13. Cyclic behavior of sandy shoals on the ebb-tidal deltas of the Wadden Sea

    NARCIS (Netherlands)

    Ridderinkhof, W.; Hoekstra, P.; van der Vegt, M.; de Swart, H. E.

    2016-01-01

    Ebb-tidal deltas are bulges of sand that are located seaward of tidal inlets. Many of these deltas feature shoals that cyclically form and migrate towards the coast. The average period between successive shoals that attach to the coast varies among different inlets. In this study, a quantitative ass

  14. High-voltage electron-microscopic observation of cyclic slip behavior around a fatigue crack tip in an iron alloy

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Yoshimasa [National Institute of Advanced Industrial Science and Technology (AIST), 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan)], E-mail: yoshim.takahashi@aist.go.jp; Tanaka, Masaki; Higashida, Kenji [Department of Materials Science and Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan); Noguchi, Hiroshi [Department of Mechanical Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan)

    2009-04-15

    The cyclic slip behavior around a fatigue crack tip originally located inside a bulk Fe-Si alloy was successfully observed by a high-voltage electron microscope in combination with a novel specimen preparation method. The method, by taking advantages of ion milling and focused ion beam techniques, ensures that the original shape of the crack tip is preserved without introducing additional slips. The observation confirms that the slip bands emitted from the fatigue crack tip are bounded by a labyrinth-like wall structure.

  15. Cyclic-Oxidation Behavior of Multilayered Pt/Ru-Modified Aluminide Coating

    Institute of Scientific and Technical Information of China (English)

    Yingxue Song; Hideyuki Murakami; Chungen Zhou

    2011-01-01

    Multilayered Pt/Ru modified aluminide coating for thermal barrier coating (TBC) systems has been investigated. 2 μm Pt+2μm Ru+2 μm Pt was first deposited on nickel-base superalloy DZ125 by electrodeposition, and then the coating was treated by annealing and a conventional pack-cementation aluminizing process. The cyclic oxidation tests were carried out at 1423 K in air. It was found that the thermal cyclic oxidation resistance of Pt/Ru-modified aluminide coating was comparable to that of Pt-modified aluminide coating, which was much better than simply aluminized DZ125. The addition of Ru to Pt-modified aluminide coating increased the resistance to rumpling. The microstructures and phase constitutions of the coating before and after oxidation were investigated.

  16. MODEST EFFECTS OF REPEATED FLUOXETINE ON ESTROUS CYCLICITY AND SEXUAL BEHAVIOR IN SPRAGUE DAWLEY FEMALE RATS

    OpenAIRE

    2008-01-01

    In an earlier study, we reported that daily fluoxetine treatment (10 mg/kg/day) rapidly disrupted estrous cyclicity and sexual receptivity in adult, regularly cycling Fischer rats. The current study was designed to investigate if comparable fluoxetine treatment would similarly affect intact, regularly cycling Sprague Dawley rats. In the first experiment, fluoxetine was injected for 24 days. After 11–14 days of daily fluoxetine treatment, 40% of the rats showed a transient disturbance of the e...

  17. Short-Term Creep Behavior of CFRP-Reinforced Wood Composites Subjected to Cyclic Loading at Different Climate Conditions

    Directory of Open Access Journals (Sweden)

    Xiaojun Yang

    2014-02-01

    Full Text Available Carbon fiber reinforced plastic (CFRP was used to adhesively reinforce Chinese fir (Cunninghamia lanceolata wood specimens. This study examined the flexural static and creep performances of CFPR-reinforced wood composites that had been subjected to changes in moisture and stress levels. The major findings were as follows: 1 the cyclic creep was slightly lower for those specimens subjected to the cyclic stress condition than for those subjected to a constant stress level due to the deflection recovery under cyclic loading; 2 the environmental conditions of high temperature and high humidity assisted in accelerating the creep by increasing the moisture content of the composite and reducing the compressive strength of wood, causing the composite specimen to fail via damage in the wood layer from compressive crushing; 3 the stress level governed the creep of the CFRP-reinforced wood composite; and 4 the Burger model was able to accurately simulate the short-term creep performance of the CFPR-reinforced wood composite. It was suggested the maximum bending stress level should be limited to 40% for the CFRP-reinforced wood composites fabricated in this study.

  18. Behavior of low-carbon steel at static and cyclic loadings

    Directory of Open Access Journals (Sweden)

    І. О. Вакуленко

    2015-03-01

    Full Text Available In the article, on the example of low-carbon steel (0.1 % C, the analysis of influence of size of grain ferrite on development of plastic flow in the conditions of static and cyclic loading is conducted. Different modes of heat treatment and thermo-mechanical treatment were applied to get experimental samples. The investigation was fulfilled using optical quantities metallography as well transmission microscopy. The assessment of separate influence of solid solution state and the ferrite grain boundaries on the yield stress and the fatigue strength of the metal was carried out by analyzing the chart type of the Hall-Petch law. The estimation of required density a mobile dislocations is carried out for maintenance of terms continuity distribution plastic flow. It was found that for low-carbon steel under cyclic loading the strengthening effect of grain boundary-prostrate exceeds solid-solution strengthening at a much finer structure compared with static stretching. To maintain the continuity propagation of plastic deformation at the same size of ferrite grain under cyclic loading conditions requires about twice as much of mobile dislocations than under the unidirectional deformation

  19. Energy Challenges: Isolating Results Due to Behavior Change

    Science.gov (United States)

    Boulton, Kelly; Pallant, Eric; Bradshaw-Wilson, Casey; Choate, Beth; Carbone, Ian

    2017-01-01

    Purpose: Approximately 700 colleges and universities have committed to climate neutrality, which will require significant reductions in energy consumption. This paper aims to explore the effectiveness of an Annual Energy Challenge in curtailing electricity use by changing consumption behaviors at one liberal arts college.…

  20. Electrochemical quartz crystal microbalance study on the two-electrode-system cyclic voltammetric behavior of Prussian blue films

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A two-channel electrochemical quartz crystal microbalance (EQCM) was used to investigate the cyclic voltammetric behavior of two Prussian blue (PB) film-modified Au electrodes in a two-electrode con-figuration in aqueous solution. The redox peaks observed in the two-electrode cyclic voltammogram (CV) are assigned to the intrinsic redox transitions among the Everitt’s salt, PB, and Prussian yellow for the film itself, the redox process of the Au substrate and the redox process of small-quantity ferri-/ferrocyanide impurities entrapped in the PB film, as also supported by ultraviolet-visible (UV-Vis) spectroelectrochemical data. The profile of the two-electrode solid-state CV for the PB powder sand-wiched between two gold-coated indium-tin oxide (ITO) electrodes is similar to that for two PB-modified Au electrodes in aqueous solution, implying similar origins for the corresponding redox peaks. The two-channel EQCM method is expected to become a highly effective technique for the studies of the two-electrode electrochemical behaviors of many other species/materials.

  1. Cyclic multiverses

    CERN Document Server

    Marosek, Konrad; Balcerzak, Adam

    2015-01-01

    Starting with the idea of regularization of singularities due to the variability of the fundamental constants in cosmology we first study the cyclic universe models. We find two models of oscillating mass density and pressure regularized by varying gravitational constant $G$. Then, we extend this idea onto the multiverse containing cyclic individual universes with either growing or decreasing entropy though leaving the net entropy constant. In order to get the key idea, we consider the doubleverse with the same geometrical evolution of the two "parallel" universes with their physical evolution (physical coupling constants $c(t)$ and $G(t)$) being different. An interesting point is that there is a possibility to exchange the universes at the point of maximum expansion -- the fact which was already noticed in quantum cosmology. Similar scenario is also possible within the framework of Brans-Dicke theory.

  2. Influence of cyclic dimer formation on the phase behavior of carboxylic acids.

    Science.gov (United States)

    Janecek, Jiri; Paricaud, Patrice

    2012-07-12

    A new thermodynamic approach based on the Sear and Jackson association theory for doubly bonded dimers [Mol. Phys.1994, 82, 1033] is proposed to describe the thermodynamic properties of carboxylic acids. The new model is able to simultaneously represent the vapor pressures, saturated densities, and vaporization enthalpies of the shortest acids and is in a much better agreement with experimental data than other approaches that do no consider the formation of cyclic dimers. The new model is applied to mixtures of carboxylic acids with nonassociating compounds, and a very good description of the vapor-liquid equilibria in mixtures of alkanes + carboxylic acids is obtained.

  3. Effect of Cyclic Pre-deformation on Uniaxial Tensile Behavior of Cu-16 at. pct Al Alloy with Low Stacking Fault Energy

    Science.gov (United States)

    Yan, Y.; Qi, C. J.; Han, D.; Ji, H. M.; Zhang, M. Q.; Li, X. W.

    2017-02-01

    To explore the effect of cyclic pre-deformation on static mechanical behavior of materials with different stacking fault energies (SFEs), polycrystalline Cu-16 at. pct Al alloy with a low SFE is selected as the target material in the present work, and the strengthening micro-mechanisms induced by cyclic pre-deformation are compared with the previous studies on pure Al with a high SFE and Cu with an intermediate SFE. The results show that the movement of dislocations exhibits a high slip planarity during cyclic pre-deformation at different total strain amplitudes Δ ɛ t/2, and some nano-sized deformation twins are formed after subsequent tension. The cyclic pre-deformation at an appropriate Δ ɛ t/2 of 1.0 × 10-3 promotes a significant increase in ultimate tensile strength σ UTS nearly without loss of tensile ductility, which primarily stems from the introduction of many mobile planar slip dislocations by cyclic pre-deformation as well as the formation of nano-sized deformation twins during subsequent tension. Based on the comparison of the strengthening micro-mechanisms induced by cyclic pre-deformation in Al, Cu, and Cu-16 at. pct Al alloy, it is deduced that a low-cycle cyclic pre-deformation at an appropriate condition is expected to cause a better strengthening effect on the static tensile properties of low SFE metals.

  4. Effect of surface deposited rare earth oxide gel characteristics on cyclic oxidation behavior of Fe20-Cr alloys

    Directory of Open Access Journals (Sweden)

    Stela Maria Cristina Fernandes

    2006-06-01

    Full Text Available Rare earths have been used to increase high temperature oxidation resistance of many chromium dioxide and alumina forming alloys. These rare earths can be added as elements (or as oxide dispersions to the alloys or applied as an oxide coating to the alloy surface. The sol-gel technique is considered to be very efficient to apply fine oxide particle coatings. Oxide gel coatings of various rare earths such as lanthanum, cerium, praseodymium, neodymium, samarium, gadolinium, dysprosium, yttrium, erbium and ytterbium have been applied to an iron-chromium alloy to determine their influence on the cyclic oxidation behavior (RT-900 °C of the alloy. The morphology and coverage of the rare earth oxide gels varied with the type of rare earth. The cyclic oxidation resistance of the alloy increased with increase in time at temperature required to reach a specific chromium dioxide layer thickness and this in turn was influenced by the rare earth ion radius and characteristics of the rare earth oxide coating such as morphology, stability, coverage, resistance to thermal stresses and consequently adhesion.

  5. Micromechanical Simulation of Thermal Cyclic Behavior of ZrO2/Ti Functionally Graded Thermal Barrier Coatings

    Directory of Open Access Journals (Sweden)

    Hideaki Tsukamoto

    2015-03-01

    Full Text Available This study numerically investigates cyclic thermal shock behavior of ZrO2/Ti functionally graded thermal barrier coatings (FG TBCs based on a nonlinear mean-field micromechanical approach, which takes into account the time-independent and dependent inelastic deformation, such as plasticity of metals, creep of metals and ceramics, and diffusional mass flow at the ceramic/metal interface. The fabrication processes for the FG TBCs have been also considered in the simulation. The effect of creep and compositional gradation patterns on micro-stress states in the FG TBCs during thermal cycling has been examined in terms of the amplitudes, ratios, maximum and mean values of thermal stresses. The compositional gradation patterns highly affect thermal stress states in case of high creep rates of ZrO2. In comparison with experimental data, maximum thermal stresses, amplitudes and ratios of thermal stresses can be effective parameters for design of such FG TBCs subject to cyclic thermal shock loadings.

  6. Cyclic Oxidation Behavior of CuCrAl Cold-Sprayed Coatings for Reusable Launch Vehicles

    Science.gov (United States)

    Raj, Sai; Karthikeyan, J.

    2009-01-01

    The next generation of reusable launch vehicles is likely to use GRCop-84 [Cu-8(at.%)Cr-4%Nb] copper alloy combustion liners. The application of protective coatings on GRCop-84 liners can minimize or eliminate many of the environmental problems experienced by uncoated liners and significantly extend their operational lives and lower operational cost. A newly developed Cu- 23 (wt.%) Cr-5% Al (CuCrAl) coating, shown to resist hydrogen attack and oxidation in an as-cast form, is currently being considered as a protective coating for GRCop-84. The coating was deposited on GRCop-84 substrates by the cold spray deposition technique, where the CuCrAl was procured as gas-atomized powders. Cyclic oxidation tests were conducted between 773 and 1,073 K to characterize the coated substrates.

  7. Instrumentation for fast-scan cyclic voltammetry combined with electrophysiology for behavioral experiments in freely moving animals

    Science.gov (United States)

    Takmakov, Pavel; McKinney, Collin J.; Carelli, Regina M.; Wightman, R. Mark

    2011-07-01

    Fast-scan cyclic voltammetry is a unique technique for sampling dopamine concentration in the brain of rodents in vivo in real time. The combination of in vivo voltammetry with single-unit electrophysiological recording from the same microelectrode has proved to be useful in studying the relationship between animal behavior, dopamine release and unit activity. The instrumentation for these experiments described here has two unique features. First, a 2-electrode arrangement implemented for voltammetric measurements with the grounded reference electrode allows compatibility with electrophysiological measurements, iontophoresis, and multielectrode measurements. Second, we use miniaturized electronic components in the design of a small headstage that can be fixed on the rat's head and used in freely moving animals.

  8. THE EFFECTS OF MONOMER STRUCTURE OF CYCLIC KETENE ACETALS ON THE BEHAVIOR OF CONTROLLED RADICAL RING-OPENING POLYMERIZATION

    Institute of Scientific and Technical Information of China (English)

    Jin-ying Yuan; Cai-yuan Pana

    2002-01-01

    Polymerization of three cyclic ketene acetals: i.e., 5,6-benzo-2-methylene-1,3-dioxepane (BMDO), 2-methylene-4-phenyl-1,3-dioxolane (MPDO) and 4,7-dimethyl-2-methylene-1,3-dioxepane (DMMDO) were carried out in the presence of ethyl α-bromobutyrate/CuBr/2,2'-bipyridine respectively. The structures ofpoly(BMDO), poly(MPDO) and poly(DMMDO)were characterized by 1H and 13C-NMR spectra. The effects of monomer structure on the behavior of atom transfer free radical ring-opening polymerization were investigated and the mechanism of controlled free radical ring-opening polymerization was discussed.

  9. Cyclic Voltammetric Studies of the Behavior of Lead-Silver Anodes in Zinc Electrolytes

    Science.gov (United States)

    Zhang, W.; Tu, C. Q.; Chen, Y. F.; Li, W. Y.; Houlachi, G.

    2013-06-01

    Cyclic voltammetry (CV) for lead-silver anodes has been performed in an acidic zinc sulfate solution with and without Mn2+ at 38 °C. It has been found that the most redox peaks observed at the lowest sweep rate of 3 mV/s in the sulfate solution could be characterized by the Nernst equation. Bubbling argon into the zinc electrolyte and increasing the potential sweep rates from 3 to 300 mV/s did not change the shape of the CV diagrams. It was also found that 0.7% silver as alloying element had an important influence on the reactions of Pb-Ag anodes in the zinc electrolyte. Lead-silver alloys were oxidized more easily in sulfuric acid than in the examined zinc electrolyte. The addition of MnSO4 to the zinc electrolyte decreased the numbers of the redox peaks on the curve of CV for lead-silver anode in zinc electrolyte.

  10. A Study on the Cyclic Oxidation Behavior of Detonation-Gun-Sprayed Ni-5Al Coatings on Inconel-718 at 900 °C

    Science.gov (United States)

    Saladi, Sekar; Menghani, Jyoti; Prakash, Satya

    2014-12-01

    Cyclic oxidation behavior of detonation-gun-sprayed Ni-5Al coating on Inconel-718 is discussed in the present study. Oxidation studies were carried out on both bare and coated superalloy substrates in air at 900 °C for 100 cycles. The thermogravimetric technique was used to establish kinetics of oxidation. X-ray diffraction, FESEM/EDAX, and x-ray mapping techniques were used to analyze the oxidation products of bare and coated samples. The weight gain of bare superalloy was higher than the Ni-5Al-coated superalloy. Both bare and Ni-5Al-coated superalloys followed nearly parabolic oxidation behavior. The Ni-5Al coating was able to reduce the overall weight gain by 26.2% in comparison with bare superalloy in the given environment. The better oxidation resistance of Ni-5Al coating may be due the formation of protective oxides phases such as NiO, Al2O3, and NiAl2O4 on the oxidized coating and Cr2O3 at the coating-substrate interface. The Ni-5Al coatings obtained from detonation-gun-spraying process showed very little porosity and low surface roughness values.

  11. Monotonic and cyclic deformation behavior of MIG-CMT welded and heat-treated joints of aluminum cast and wrought alloys

    Energy Technology Data Exchange (ETDEWEB)

    Kantehm, Matthias; Soeker, Marcus; Krupp, Ulrich; Michels, Wilhelm [Faculty of Engineering and Computer Science, Institute of Materials Design and Structural Integrity, University of Applied Sciences Osnabrueck, 49009 Osnabrueck (Germany)

    2012-10-15

    While the fatigue behavior of die cast aluminum as well as welded aluminum wrought alloys have been subject of several studies, no systematic work has been carried out on hybrid structures made as a combination of welded sand castings and wrought alloys. Aim of the present study is to correlate the monotonic and cyclic deformation behavior of thin sheet welded joints with the microstructure in the heat affected zone of the material combination sand cast EN AC-Al Si7Mg0.3 and wrought alloy EN AW-Al Si1MgMn (EN AW-6082). The metal sheets were welded using a metal inert gas cold metal transfer process under variation of the welding gap, the heat treatment parameters, as well as the surface finishes. It was demonstrated by Woehler diagrams based on bending fatigue tests that the fatigue life could be increased for the welded and heat treated specimens as compared to the as-received cast specimens. By means of optical microscopy this effect was attributed to microstructural changes due to the optimized welding and heat treatment process. A detailed analysis of the mechanical tests was possible by the application of an optical 3D strain analysis. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  12. Seismic Behavior of Frame with Specially Shaped Columns Subjected to Cyclic Load

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In order to study the seismic behavior of frame with specially shaped columns, the hysteretic curve was analyzed based on a quasi-static test of a two-span, three-story frame with specially shaped columns. The top layer framework curve and the corresponding resilience model were obtained from the hysteretic curve. And the stiffness and strength degeneration were also investigated.The results indicated that the stiffness degeneration is not obvious, thus the frame with specially shaped columns has high earthquake-resistant behavior. The resilience model calculated from the test can provide reference for design and nonlinear finite element analysis.

  13. The effect of combined cyclic mechanical stretching and microgrooved surface topography on the behavior of fibroblasts

    NARCIS (Netherlands)

    Loesberg, W.A.; Walboomers, X.F.; Loon, J.J. van; Jansen, J.A.

    2005-01-01

    Under the influence of mechanical stress, cultured fibroblasts have a tendency to orient themselves perpendicular to the stress direction. Similar cell alignment can be induced by guiding cells along topographical clues, like microgrooves. The aim of this study was to evaluate cell behavior on micro

  14. Influence of deformation behavior, oxydation, and temperature on the long time cyclic stress behavior of high temperature steels

    Science.gov (United States)

    Maile, K.

    1982-01-01

    The influence of different parameters on the creep-fatigue behavior of several steel alloys was investigated. The higher the temperature the lower the crack initiation value. Pauses during the cycle reduce the damage. Oxidation reduces and protective gas increases the lifetime. Prior loading and prior deformation reduce the lifetime. Short annealing slightly affects the cycle stress behavior. The test results do not satisfactorily agree with methods of extrapolation and damage accumulation.

  15. Constitutive Cyclic Deformation Behavior in Single-crystal and Directionally Solidified SSME High-pressure Fuel Turbopump Airfoil Materials

    Science.gov (United States)

    Milligan, W. W.; Huron, E. S.; Antolovich, S. D.

    1985-01-01

    The major goal of the project is to correlate mechanical properties with microstructural deformation behavior and to develop models for constitutive response under a variety of monotonic and cyclic loading cycles, temperatures, strain levels, strain rates, and environments. Two alloys are being studied as candidate SSME turbine blade materials. The first is PWA 1480, which is a single-crystal alloy whose nominal composition is reported. The second alloy being studied is D.S. Mar-M 246 + Hf. This is a directionally solidified material, and its nominal composition is also reported. The major areas of interest for the two materials will be slightly different. The single-crystal alloy lends itself well to fundamental deformation studies, since resolved shear stresses on slip planes are all known and only one grain is present. The D.S. material presents an excellent opportunity to study the effects of slightly misaligned grains on deformation behavior. The two materials will be studied by using approximately the same test matrix, so a good degree of direct comparison will also be possible.

  16. Cyclic multiverses

    Science.gov (United States)

    Marosek, Konrad; Dąbrowski, Mariusz P.; Balcerzak, Adam

    2016-09-01

    Using the idea of regularization of singularities due to the variability of the fundamental constants in cosmology we study the cyclic universe models. We find two models of oscillating and non-singular mass density and pressure (`non-singular' bounce) regularized by varying gravitational constant G despite the scale factor evolution is oscillating and having sharp turning points (`singular' bounce). Both violating (big-bang) and non-violating (phantom) null energy condition models appear. Then, we extend this idea on to the multiverse containing cyclic individual universes with either growing or decreasing entropy though leaving the net entropy constant. In order to get an insight into the key idea, we consider the doubleverse with the same geometrical evolution of the two `parallel' universes with their physical evolution [physical coupling constants c(t) and G(t)] being different. An interesting point is that there is a possibility to exchange the universes at the point of maximum expansion - the fact which was already noticed in quantum cosmology. Similar scenario is also possible within the framework of Brans-Dicke theory where varying G(t) is replaced by the dynamical Brans-Dicke field φ(t) though these theories are slightly different.

  17. Monotonic and Cyclic Bond Behavior of Deformed CFRP Bars in High Strength Concrete

    OpenAIRE

    2016-01-01

    Composite reinforcing bars (rebars) that are used in concrete members with high performance (strength and durability) properties could have beneficial effects on the behavior of these members. This is especially vital when a building is constructed in an aggressive environment, for instance a corrosive environment. Although tension capacity/weight (or volume) ratios in composite rebars (carbon fiber reinforced polymer (CFRP), glass fiber reinforced polymer (GFRP), etc.) are very high when com...

  18. Cyclical Behavior of Inventories and Growth Projections Recent Evidence From Europe and the United States

    OpenAIRE

    Alexander W. Hoffmaister; Jens R Clausen

    2010-01-01

    In the United States and a few European countries, inventory behavior is mainly the outcome of demand shocks: a standard buffer-stock model best characterizes these economies. But most European countries are described by a modified buffer-stock model where supply shocks dominate. In contrast to the United States, inventories boost growth with a one-year lag in Europe. Moreover, inventories provide limited information to improve growth forecasts particularly when a modified buffer-stock model ...

  19. Enhancing the Electrochemical Behavior of Pure Copper by Cyclic Potentiodynamic Passivation: A Comparison between Coarse- and Nano-Grained Pure Copper

    Science.gov (United States)

    Fattah-alhosseini, Arash; Imantalab, Omid; Attarzadeh, Farid Reza

    2016-10-01

    Electrochemical behavior of coarse- and nano-grained pure copper were modified and improved to a large extent by the application of cyclic potentiodynamic passivation. The efficacy of this method was evaluated on the basis of grain size which is of great importance in corrosion studies. In this study, the eight passes of accumulative roll bonding process at room temperature were successfully performed to produce nano-grained pure copper. Transmission electron microscopy image indicated that the average grain size reached below 100 nm after eight passes. On the basis of cyclic voltammetry and also the electrochemical tests performed after that, it was revealed that cyclic potentiodynamic passivation had a significant improving effect on the passive behavior of both coarse- and nano-grained samples. In addition, a superior behavior of nano-grained sample in comparison to coarse-grained one was distinguished by its smaller cyclic voltammogram loops, nobler free potentials, larger capacitive arcs in the Nyquist plots, and less charge carrier densities within the passive film.

  20. Simultaneous Investigation of the Effect of Advanced Thermomechanical Treatment and Repetitive Cyclic Voltammetry on the Electrochemical Behavior of AISI 430 Ferritic Stainless Steel

    Science.gov (United States)

    Vafaeian, Saeed; Fattah-alhosseini, Arash; Keshavarz, Mohsen K.; Mazaheri, Yousef

    2017-01-01

    In this study, it was revealed that the electrochemical behavior of AISI 430 ferritic stainless steel can be modified and improved to a large extent by the application of repetitive cyclic voltammetry in the anodic polarization branch of the alloy. The efficiency of this method was evaluated on the basis of the alloy grain size which is of great importance in corrosion studies. In fact, a coarse grain structure versus a fine grain structure was the subject of the used surface treatment method. Coarsening and refining of the grain size were conducted through a heat treatment and an advanced thermomechanical process. On the basis of cyclic voltammetry tests and also the electrochemical tests performed after that, it was shown that cyclic voltammetry had a significant improving effect on the passive behavior of both fine- and coarse-grained samples. Moreover, superior behavior of fine-grained sample in comparison with coarse-grained one was distinguished by its smaller cyclic voltammogram loops, more noble free potentials, larger capacitive arcs in the Nyquist plots, and less charge carrier densities within the passive film.

  1. Simultaneous Investigation of the Effect of Advanced Thermomechanical Treatment and Repetitive Cyclic Voltammetry on the Electrochemical Behavior of AISI 430 Ferritic Stainless Steel

    Science.gov (United States)

    Vafaeian, Saeed; Fattah-alhosseini, Arash; Keshavarz, Mohsen K.; Mazaheri, Yousef

    2017-02-01

    In this study, it was revealed that the electrochemical behavior of AISI 430 ferritic stainless steel can be modified and improved to a large extent by the application of repetitive cyclic voltammetry in the anodic polarization branch of the alloy. The efficiency of this method was evaluated on the basis of the alloy grain size which is of great importance in corrosion studies. In fact, a coarse grain structure versus a fine grain structure was the subject of the used surface treatment method. Coarsening and refining of the grain size were conducted through a heat treatment and an advanced thermomechanical process. On the basis of cyclic voltammetry tests and also the electrochemical tests performed after that, it was shown that cyclic voltammetry had a significant improving effect on the passive behavior of both fine- and coarse-grained samples. Moreover, superior behavior of fine-grained sample in comparison with coarse-grained one was distinguished by its smaller cyclic voltammogram loops, more noble free potentials, larger capacitive arcs in the Nyquist plots, and less charge carrier densities within the passive film.

  2. Effect of minor alloying elements La, C and B on the cyclic oxidation behavior of Ni-Cr-W-Mo superalloys

    Science.gov (United States)

    Yun, Dae Won; Seo, Seong Moon; Jeong, Hi Won; Yoo, Young Soo

    2017-09-01

    The cyclic oxidation behavior of Ni-Cr-W-Mo base alloys with various La, C and B contents is investigated at 1150 °C in ambient air with 15 min of high-temperature exposure and 5 min of air cooling. Oxidation resistance is evaluated by the weight change during cyclic oxidation. The cross-section of the oxide scale is observed by scanning electron microscopy after the cyclic oxidation test. The oxide scale mainly consists with spinels and a chromia layer. NiWO4 oxide particles and NiO are also observed in some areas. The addition of La improves the cyclic oxidation resistance significantly. However, the addition of 0.03 wt% B reduces the beneficial effect of La. The additions of B and C increase the spallation at the initial stage such that severe weight loss is observed. However, the spallation is reduced at the later stage. The addition of a proper amounts of B and C can be beneficial to improve the cyclic oxidation resistance of Ni-Cr-W-Mo alloys.

  3. Delamination growth behavior in cross-ply composites under compressive cyclic (fatigue) loading

    Science.gov (United States)

    Pelegri, Assimina A.

    A mode dependent fatigue delamination growth law for anisotropic composite plates is presented in this thesis. The novelty of the presented law lies in the mode dependency of the material and laminate constants m(Psi) and C(Psi). The model describing the mode dependent delamination growth law consists of an initial postbuckling solution accounting for general delaminated composites, i.e. with no restrictive assumptions on the delamination dimensions, and a fracture mechanics solution. A numerical code was developed for the implementation of the closed form solution which gives the loading and geometrical quantities as well as the energy release rates and the mode mixities. The computer code was especially designed for parametric studies. Parameters assigned in this particular investigation were: end conditions, delamination position (h/T), and applied strain. The effect of the end conditions, i.e. clamped-clamped versus simply-supported ends on the initial postbuckling and growth behavior of delaminated plates was also investigated. In conjunction with the previous analysis, a detailed experimental study was designed and carried out in order to validate the proposed model. The tests were designed so that the effect of certain parameters on the delamination growth behavior could be evaluated. The parameters included in the investigation were: initial delamination length, applied strain and delamination position (h/T). Compressive static, compressive fatigue (constant displacement amplitude), and double cantilever beam (DCB) tests were conducted. Data acquisition and analysis for these tests were performed. By comparing analytical and experimental results it is shown that a very good correlation exists, and the presented mode dependent fatigue delamination growth law can accurately predict fatigue lives of delaminated composite structures.

  4. Maladaptive Behavior Differences in Prader-Willi Syndrome Due to Paternal Deletion versus Maternal Uniparental Disomy.

    Science.gov (United States)

    Dykens, Elisabeth M.; King, Bryan H.; Cassidy, Suzanne B.

    1999-01-01

    This study compared maladaptive behavior in 23 people with Prader-Willi syndrome due to paternal deletion and in 23 age- and gender-matched subjects with maternal uniparental disomy. Controlling for IQs, the deletion cases showed significantly higher maladaptive ratings, more symptom-related distress, and more behavior problems. Findings suggest a…

  5. Cyclic-Tension Fatigue Behavior in a SS400 Steel Plate Studied Using Ultrasonic Linear and Nonlinear Techniques

    Science.gov (United States)

    Yamagishi, Hideki; Fukuhara, Mikio

    2015-11-01

    Three acoustic probe configurations were used to assess cyclic-tension fatigue in SS400 steel at room temperature via a diffracted horizontally polarized shear wave (SH) transmission method. Linear analysis of the propagation time and amplitude of shear and longitudinal waves with fatigue progression revealed that the linear behavior was governed by residual stress, attributed to the acoustoelastic effect. Specifically, the propagation time of the shear waves increased and the wave amplitude decreased with fatigue progression. Our results also revealed that the propagation paths of the waves became deeper with progressive fatigue. Additionally, when the probe angle was optimized for diffraction, the estimated change in the length prior to fatigue breakage was 0.61 pct. Nonlinear analysis results revealed that second harmonic β-parameters increased as fatigue progressed, up to ~800 pct for the optimal frequency configuration; this was attributed to an increase in the number of dislocation-associated viscoelastic effects. The proposed approach shows great potential for nondestructive evaluation of metal fatigue via parameter analysis of residual stress and dislocation variations.

  6. Thermal Fatigue Behavior of Air-Plasma Sprayed Thermal Barrier Coating with Bond Coat Species in Cyclic Thermal Exposure

    Directory of Open Access Journals (Sweden)

    Ungyu Paik

    2013-08-01

    Full Text Available The effects of the bond coat species on the delamination or fracture behavior in thermal barrier coatings (TBCs was investigated using the yclic thermal fatigue and thermal-shock tests. The interface microstructures of each TBC showed a good condition without cracking or delamination after flame thermal fatigue (FTF for 1429 cycles. The TBC with the bond coat prepared by the air-plasma spray (APS method showed a good condition at the interface between the top and bond coats after cyclic furnace thermal fatigue (CFTF for 1429 cycles, whereas the TBCs with the bond coats prepared by the high-velocity oxygen fuel (HVOF and low-pressure plasma spray (LPPS methods showed a partial cracking (and/or delamination and a delamination after 780 cycles, respectively. The TBCs with the bond coats prepared by the APS, HVOF and LPPS methods were fully delaminated (>50% after 159, 36, and 46 cycles, respectively, during the thermal-shock tests. The TGO thickness in the TBCs was strongly dependent on the both exposure time and temperature difference tested. The hardness values were found to be increased only after the CFTF, and the TBC with the bond coat prepared by the APS showed the highest adhesive strength before and after the FTF.

  7. Creep behavior of hand-mixed Simplex P bone cement under cyclic tensile loading.

    Science.gov (United States)

    Verdonschot, N; Huiskes, R

    1994-01-01

    Acrylic cement, used for the fixation of total hip replacements and other orthopedic implants, is a subject of renewed scientific interest as a result of recent hypotheses about dynamic, long-term mechanical failure mechanisms suspected to play a role in prosthetic loosening. Little is known, however, about the long-term mechanical behavior of cement. In this study, the dynamic creep deformation of hand mixed acrylic cement was examined in laboratory tests. Strain patterns found represented the familiar creep process consisting of a primary, a secondary, and a tertiary creep phase. Specimens dynamically loaded with a maximum stress of 3 MPa from 0 were subject to creep of about 50% of the elastic strain after 250 000 loading cycles. A linear relationship between the logarithmic values of the creep-strain and the number of loading cycles was found. Specimens exposed to higher loads showed significantly higher creep-strains. No relationship could be established between the strain levels and the porosity of the specimens. Specimens dynamically loaded with a maximal stress of 7 or 11 MPa from 0 failed during the tests. The number of loading cycles to failure was similar to fatigue strength data reported in earlier literature.

  8. Comportamiento de viviendas de ferrocemento bajo cargas cíclic Behavior of ferrocement housing under cyclical loads

    Directory of Open Access Journals (Sweden)

    Daniel Bedoya Ruiz

    2009-07-01

    Full Text Available La escasez de vivienda en el mundo ha llevado desde hace varios años a la búsqueda de nuevos materiales y sistemas alternativos para su construcción. El ferrocemento desde hace más de 25 décadas viene siendo estudiado y aplicado como solución de vivienda en varios países; Colombia, uno de ellos. En este trabajo se presenta parte de los resultados de una investigación acerca del comportamiento de las viviendas de ferrocemento bajo cargas cíclicas. Se probaron dos módulos de vivienda a escala real construidos con paneles prefabricados de pared delgada de ferrocemento. Sobre cada módulo de ferrocemento se realizaron ensayos de carga cíclica y se evaluó su comportamiento. Los resultados obtenidos muestran la sensibilidad de este sistema estructural ante varios ciclos de carga, con pérdidas de rigidez cercanas al 20% para los primeros ciclos y hasta un 85% al final de los mismos.The shortage of dwelling in the world has taken for several years to the search of new materials and alternative systems for its construction. For more than 25 decades, ferrocement has been studied and applied as a dwelling solution in several countries, among them Colombia.. This article refers to the results of a research about seismic behavior of ferrocement dwellings. Two modules built on real scale with prefabricated panels of ferrocement thin wall were used. On each module of ferrocement, tests of cyclical load were carried out, and its behavior was evaluated. The obtained results showed the sensitivity of this structural system under several cycles of load, with losses of rigidity near to 20% for the first cycles and up to 85% at the end of the same.

  9. Does cyclic stress and accelerated ageing influence the wear behavior of highly crosslinked polyethylene?

    Science.gov (United States)

    Affatato, Saverio; De Mattia, Jonathan Salvatore; Bracco, Pierangiola; Pavoni, Eleonora; Taddei, Paola

    2016-06-01

    First-generation (irradiated and remelted or annealed) and second-generation (irradiated and vitamin E blended or doped) highly crosslinked polyethylenes were introduced in the last decade to solve the problems of wear and osteolysis. In this study, the influence of the Vitamin-E addition on crosslinked polyethylene (XLPE_VE) was evaluated by comparing the in vitro wear behavior of crosslinked polyethylene (XLPE) versus Vitamin-E blended polyethylene XLPE and conventional ultra-high molecular weight polyethylene (STD_PE) acetabular cups, after accelerated ageing according to ASTM F2003-02 (70.0±0.1°C, pure oxygen at 5bar for 14 days). The test was performed using a hip joint simulator run for two millions cycles, under bovine calf serum as lubricant. Mass loss was found to decrease along the series XLPE_VE>STD_PE>XLPE, although no statistically significant differences were found between the mass losses of the three sets of cups. Micro-Raman spectroscopy was used to investigate at a molecular level the morphology changes induced by wear. The spectroscopic analyses showed that the accelerated ageing determined different wear mechanisms and molecular rearrangements during testing with regards to the changes in both the chain orientation and the distribution of the all-trans sequences within the orthorhombic, amorphous and third phases. The results of the present study showed that the addition of vitamin E was not effective to improve the gravimetric wear of PE after accelerated ageing. However, from a molecular point of view, the XLPE_VE acetabular cups tested after accelerated ageing appeared definitely less damaged than the STD_PE ones and comparable to XLPE samples.

  10. Furnace Cyclic Behavior of Plasma-Sprayed Zirconia-Yttria and Multi-Component Rare Earth Oxide Doped Thermal Barrier Coatings

    Science.gov (United States)

    Zhu, Dongming; Nesbitt, James A.; McCue, Terry R.; Barrett, Charles A.; Miller, Robert A.

    2002-01-01

    Ceramic thermal barrier coatings will play an increasingly important role in advanced gas turbine engines because of their ability to enable further increases in engine temperatures. However, the coating performance and durability become a major concern under the increasingly harsh thermal cycling conditions. Advanced zirconia- and hafnia-based cluster oxide thermal barrier coatings with lower thermal conductivity and improved thermal stability are being developed using a high-heat-flux laser-rig based test approach. Although the new composition coatings were not yet optimized for cyclic durability, an initial durability screening of numerous candidate coating materials was carried out using conventional furnace cyclic tests. In this paper, furnace thermal cyclic behavior of the advanced plasma-sprayed zirconia-yttria-based thermal barrier coatings that were co-doped with multi-component rare earth oxides was investigated at 1163 C using 45 min hot cycles. The ceramic coating failure mechanisms were studied by using scanning electron microscopy combined with X-ray diffraction phase analysis after the furnace tests. The coating cyclic lifetime will be discussed in relation to coating phase structures, total dopant concentrations, and other properties.

  11. Experimental study on the stability of plate anchors in clay under cyclic loading

    Directory of Open Access Journals (Sweden)

    Long Yu

    2015-03-01

    Full Text Available Although the bearing capacity of plate anchors in clay has been studied extensively, the results considering the effects of offshore cyclic loading are relatively rare. In the present study, 1 g model tests are carried out to investigate the effect of cyclic loading on the bearing capacity of plate anchors in clay. The ultimate pullout capacity of plate anchors in clay decreases as the accumulated plastic shear strain grows due to the strain-softening of clay under cyclic loading. The load–displacement curves of these tests are presented and the effects of overburden stress and cyclic loading amplitude on the strain-softening behavior are discussed.

  12. Cyclic derangements

    CERN Document Server

    Assaf, Sami H

    2010-01-01

    A classic problem in enumerative combinatorics is to count the number of derangements, that is, permutations with no fixed point. Inspired by a recent generalization to facet derangements of the hypercube by Gordon and McMahon, we generalize this problem to enumerating derangements in the wreath product of any finite cyclic group with the symmetric group. We also give q- and (q, t)-analogs for cyclic derangements, generalizing results of Brenti and Gessel.

  13. Cyclic Voltammetry Experiment.

    Science.gov (United States)

    Van Benschoten, James J.; And Others

    1983-01-01

    Describes a three-part experiment designed to introduce cyclic voltammetry to graduate/undergraduate students. Part 1 demonstrates formal reduction potential, redox electron transfer, diffusion coefficient, and electrochemical reversibility. Part 2 investigates electrochemical behavior of acetaminophen. Part 3 examines such experimental variables…

  14. Cyclic Voltammetry Experiment.

    Science.gov (United States)

    Van Benschoten, James J.; And Others

    1983-01-01

    Describes a three-part experiment designed to introduce cyclic voltammetry to graduate/undergraduate students. Part 1 demonstrates formal reduction potential, redox electron transfer, diffusion coefficient, and electrochemical reversibility. Part 2 investigates electrochemical behavior of acetaminophen. Part 3 examines such experimental variables…

  15. Cyclic Deformation Behavior of Fe-18Cr-18Mn-0.63N Nickel-Free High-Nitrogen Austenitic Stainless Steel

    Science.gov (United States)

    Shao, C. W.; Shi, F.; Li, X. W.

    2015-04-01

    Cyclic deformation and damage behavior of a Ni-free high-nitrogen austenitic stainless steel with a composition of Fe-18Cr-18Mn-0.63N (weight pct) were studied, and the internal stress and effective stress were estimated by partitioning the hysteresis loop during cyclic straining at total strain amplitudes ranging from 3.0 × 10-3 to 1.0 × 10-2. It is found that immediate cyclic softening takes place at all strain amplitudes and subsequently a saturation or quasi-saturation state develops and occupies the main part of the whole fatigue life. The internal stress increases with increasing strain amplitude, while the variation of effective stress with strain amplitude is somewhat complicated. Such a phenomenon is discussed in terms of dislocation structures and the short-range ordering caused by the interaction between nitrogen atoms and substitutional atoms. The relationship of fatigue life vs plastic strain amplitude ( N f-Δ ɛ pl/2) follows a bilinear Coffin-Manson rule, resulting from the variation in slip deformation mode with the applied strain amplitude. At the low strain amplitude, cracks initiate along slip bands, and planar slip dislocation configurations dominate the major characteristic of internal microstructures. At high strain amplitudes, intergranular (mostly along grain boundaries and few along twin boundaries) cracks are generally found, and the deformation microstructures are mainly composed of dislocation cells, stacking faults and a small amount of deformation twins, in addition to planar slip dislocation structures.

  16. 钢管橡胶混凝土柱滞回性能分析%Analytical Behavior of Rubber Concrete-Filled steel Tubular Columns under Cyclic Loading

    Institute of Scientific and Technical Information of China (English)

    刘艳华; 王铁良; 刘文合; 李玉清

    2014-01-01

    采用有限元分析的方法,对钢管橡胶混凝土柱荷载-位移滞回关系曲线进行计算,并系统分析钢管截面形式和橡胶粉取代率等参数对滞回曲线骨架线、承载力退化曲线、刚度退化曲线的影响。结果表明:有限元计算结果与试验结果符合较好,钢管橡胶混凝土具有较好的滞回性能。%Waste rubber processing has become a global environment and resources problems. Crushed waste rubber into rubber powder,and added into concrete,the formed of rubber concrete used as a building material,can not only achieve the utilization of waste,but also has significance for environmental protection. The cyclic behavior of rubber concrete-filled steel tubular columns was studied in this paper. The cyclic load versus later-al displacement hysteretic curve was calculated by using finite element analysis(FEA)model to investigate the behavior of the columns. Based on the theoretical model,the influences of different column cross-section type and rubber replacing ratio on the lateral load versus lateral displacement skeleton curves,capacity reduction curves and rigidity degradation curves of rubber concrete-filled steel tubular columns were discussed. Analysis shows that the predicted cyclic responses for the composite columns are in good agreement with the test results. The rubber concrete-filled steel tu-bular columns have good dynamic behaviors. The results indicate to be used for elastico-plastic analysis of the structural system.

  17. Influence of cyclic dimer formation on the phase behavior of carboxylic acids. II. Cross-associating systems.

    Science.gov (United States)

    Janeček, Jiří; Paricaud, Patrice

    2013-08-15

    The doubly bonded dimer association scheme (DBD) proposed by Sear and Jackson is extended to mixtures exhibiting both self- and cross-associations. The PC-SAFT equation of state is combined with the new DBD association contribution to describe the vapor-liquid equilibria of binary mixtures of carboxylic acids + associating compounds (water, alcohols, and carboxylic acids). The effect of doubly bonded dimers on the phase behavior in such systems is less important than in mixtures of carboxylic acids with nonassociating compounds, due to the cross-associations that compete with the formation of DBDs. Nevertheless, a clear improvement in the description of vapor-liquid coexistence curves is achieved over the classical 2B association model, particularly for the dew point curves.

  18. Material characterization and finite element modelling of cyclic plasticity behavior for 304 stainless steel using a crystal plasticity model

    OpenAIRE

    Lu, Jiawa; Sun, Wei; Becker, Adib A.

    2016-01-01

    Low cycle fatigue tests were carried out for a 304 stainless steel at room temperature. A series of experimental characterisations, including SEM, TEM, and XRD were conducted for the 304 stainless steel to facilitate the understanding of the mechanical responses and microstructural behaviour of the material under cyclic loading including nanostructure, crystal structure and the fractured surface. The crystal plasticity finite element method (CPFEM) is a powerful tool for studying the microstr...

  19. Numerical modeling of centrifuge cyclic lateral pile load experiments

    Institute of Scientific and Technical Information of China (English)

    Nikos Gerolymos; Sandra Escoffer; George Gazetas; Jacques Gamier

    2009-01-01

    To gain insight into the inelastic behavior of piles, the response of a vertical pile embedded in dry sand and subjected to cyclic lateral loading was studied experimentally in centrifuge tests conducted in Laboratoire Central des Ponts et Chaussees. Three types of cyclic loading were applied, two asymmetric and one symmetric with respect to the unloaded pile. An approximately square-root variation of soil stiffness with depth was obtained from indirect in-flight density measurements, laboratory tests on reconstituted samples, and well-established empirical correlations. The tests were simulated using a cyclic nonlinear Winkler spring model, which describes the full range of inelastic phenomena, including separation and re-attachment of the pile from and to the soil. The model consists of three mathematical expressions capable of reproducing a wide variety of monotonic and cyclic experimental p-y curves. The physical meaning of key model parameters is graphically explained and related to soil behavior. Comparisons with the centrifuge test results demonstrate the general validity of the model and its ability to capture several features of pile-soil interaction, including: soil plastification at an early stage of loading, "pinching" behavior due to the formation of a relaxation zone around the upper part of the pile, and stiffness and strength changes due to cyclic loading. A comparison of the p-y curves derived from the test results and the proposed model, as well as those from the classical curves of Reese et al. (1974) for sand, is also presented.

  20. Cyclic Voltammetry.

    Science.gov (United States)

    Evans, Dennis H.; And Others

    1983-01-01

    Cyclic voltammetry is a simple experiment that has become popular in chemical research because it can provide useful information about redox reactions in a form which is easily obtained and interpreted. Discusses principles of the method and illustrates its use in the study of four electrode reactions. (Author/JN)

  1. Cyclic Voltammetry.

    Science.gov (United States)

    Evans, Dennis H.; And Others

    1983-01-01

    Cyclic voltammetry is a simple experiment that has become popular in chemical research because it can provide useful information about redox reactions in a form which is easily obtained and interpreted. Discusses principles of the method and illustrates its use in the study of four electrode reactions. (Author/JN)

  2. The effect of 0.1 atomic percent zirconium on the cyclic oxidation behavior of beta-NiAl for 3000 hours at 1200 C

    Science.gov (United States)

    Barrett, C. A.

    1989-01-01

    The long time effect of 0.1 at percent Zr (0.2 wt percent Zr) on the cyclic oxidation behavior of hipped beta-NiAl was studied. Oxidation testing was performed in static air at 1200 C for up to 3000 one-hour exposure cycles. Specific weight change versus time data was modeled with the COSP computer program to analyze cyclic oxidation behavior. The Zr-free stoichiometric alloy oxidized and spalled randomly to bare metal between cycles at a rate high enough to deplete Al to a low enough level that oxidation breakaway took place as nonprotective NiO replaced the alpha-Al203/NiAl204 scale as the controlling oxide. The Zr minimized this severe type of spalling maintaining the protective alpha-Al203 scale even out to 3000 hours for the stoichiometric alloy with no significant Al depletion. A third beta-NiAl alloy containing 0.1 at percent Zr but with 10 percent less Al than the stoichiometric alloy was also tested and showed some depletion of Al, but the protective Al203/NiAl204 was still maintained to close to 2700 hours.

  3. The effect of 0.1 atomic percent zirconium on the cyclic oxidation behavior of beta-NiAl for 300 hours at 1200 C

    Science.gov (United States)

    Barrett, C. A.

    1988-01-01

    The long time effect of 0.1 at percent Zr (0.2 wt percent Zr) on the cyclic oxidation behavior of hipped beta-NiAl was studied. Oxidation testing was performed in static air at 1200 C for up to 3000 one-hour exposure cycles. Specific weight change versus time data was modeled with the COSP computer program to analyze cyclic oxidation behavior. The Zr-free stoichiometric alloy oxidized and spalled randomly to bare metal between cycles at a rate high enough to deplete Al to a low enough level that oxidation breakaway took place as nonprotective NiO replaced the alpha-Al2O3/NiAl2O4 scale as the controlling oxide. The Zr minimized this severe type of spalling maintaining the protective alpha-Al2O3 scale even out to 3000 hours for the stoichiometric alloy with no significant Al depletion. A third beta-NiAl alloy containing 0.1 at percent Zr but with 10 percent less Al than the stoichiometric alloy was also tested and showed some depletion of Al, but the protective Al2O3/NiAl2O4 was still maintained to close to 2700 hours.

  4. Complex behavior of internal collapse due to self-generated radial electric field

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, Taro; Tokuda, Shinji; Kishimoto, Yasuaki; Takizuka, Tomonori [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment; Naitou, Hiroshi [Department of Electical and Electronic Engineering, Yamaguchi University, Ube, Yamaguchi (Japan)

    2000-07-01

    The density gradient effect is taken into account in the gyro-kinetic nonlinear simulation of the kinetic m=1 internal kink mode to clarify the nonlinear behavior of the internal collapse. Even when the density gradient is not so large enough to change the process of the full reconnection, the later process is changed considerably due to the self-generated radial electric field. The nonlinear growth of the 0/0 mode after the internal collapse violates the symmetrical flow of the parallel current, restricting the secondary reconnection. (author)

  5. Hopf cyclic cohomology and transverse characteristic classes

    CERN Document Server

    Moscovici, Henri

    2010-01-01

    By refining the cyclic cohomological apparatus for computing the Hopf cyclic cohomology of the Hopf algebras associated to infinite primitive Cartan-Lie pseudogroup, we explicitly identify, as a Hopf cyclic complex, the image of the canonical homomorphism from the Gelfand-Fuks complex to the Bott complex for equivariant cohomology. Distinct from the original realization due to A. Connes and the first named author of the cyclic cohomology of such Hopf algebras as differentiable cyclic cohomology, this construction provides a convenient front-end model for their Hopf cyclic cohomology. Relying on it, we produce characteristic homomorphisms from newly developed models for Hopf cyclic characteristic classes to the cyclic cohomology of the convolution algebras of \\'etale holonomy groupoids, which in particular work in the relative case with no compactness restriction. As an illustration, we apply the latter feature to transfer the universal Hopf cyclic Chern classes found by us in a previous paper, and produce in ...

  6. Infertility in Female Mice with a Gain-of-Function Mutation in the Luteinizing Hormone Receptor Is Due to Irregular Estrous Cyclicity, Anovulation, Hormonal Alterations, and Polycystic Ovaries.

    Science.gov (United States)

    Hai, Lan; McGee, Stacey R; Rabideau, Amanda C; Paquet, Marilène; Narayan, Prema

    2015-07-01

    The luteinizing hormone receptor, LHCGR, is essential for fertility in males and females, and genetic mutations in the receptor have been identified that result in developmental and reproductive defects. We have previously generated and characterized a mouse model (KiLHR(D582G)) for familial male-limited precocious puberty caused by an activating mutation in the receptor. We demonstrated that the phenotype of the KiLHR(D582G) male mice is an accurate phenocopy of male patients with activating LHCGR mutations. In this study, we observed that unlike women with activating LHCGR mutations who are normal, female KiLHR(D582G) mice are infertile. Mice exhibit irregular estrous cyclicity, anovulation, and precocious puberty. A temporal study from 2-24 wk of age indicated elevated levels of progesterone, androstenedione, testosterone, and estradiol and upregulation of several steroidogenic enzyme genes. Ovaries of KiLHR(D582G) mice exhibited significant pathology with the development of large hemorrhagic cysts as early as 3 wk of age, extensive stromal cell hyperplasia and hypertrophy with luteinization, numerous atretic follicles, and granulosa cell tumors. Ovulation could not be rescued by the addition of exogenous gonadotropins. The body weights of the KiLHR(D582G) mice were higher than wild-type counterparts, but there was no increase in the body fat composition or metabolic abnormalities such as impaired glucose tolerance and insulin resistance. These studies demonstrate that activating LHCGR mutations do not produce the same phenotype in female mice as in humans and clearly illustrate species differences in the expression and regulation of LHCGR in the ovary, but not in the testis. © 2015 by the Society for the Study of Reproduction, Inc.

  7. Gambling Disorder Due to Brazilian Animal Game ("Jogo do bicho"): Gambling Behavior and Psychopathology.

    Science.gov (United States)

    Medeiros, Gustavo; Grant, Jon; Tavares, Hermano

    2016-03-01

    Gambling is currently widespread across the globe and despite legally restricted, it is significantly common in Brazil. A traditional and common form of gambling in Brazil is the Brazilian animal game (BAG)--"Jogo do bicho" in Portuguese. In 2013, BAG activities collected approximately 19 billion Brazilian reais--equivalent to more than 8 billon American dollars, a figure almost 60 % higher than legal lotteries. Although a common form of gambling, the gambling behavior and psychopathology of gambling disorder (GD) associated with BAG has never been systematically studied. The aim of this study is to conduct, the first research approaching GD due to BAG. We assessed 897 participants of whom 63 subjects (7.0 %) presented with GD due to BAG and 834 with GD associated with other forms of gambling. After comparing these two groups, major differences were found in demographics, gambling behavior elements and psychopathological variables. This research reinforces the need for further research on BAG and the need for specific approaches in GD. The particularities of BAG may affect treatment strategies as, for example, suggest some adaptations in social and psychotherapeutic approaches. We also highlight the need to acknowledge the "hidden" BAG as a potential addictive game.

  8. Temperature and grain size effects on the behavior of CuAlBe SMA wires under cyclic loading

    Energy Technology Data Exchange (ETDEWEB)

    Araya, Rodrigo; Marivil, Marco; Mir, Cristobal [Universidad de Chile, Facultad de Ciencias Fisicas y Matematicas, Beaucheff 850, Santiago (Chile); Moroni, Ofelia [Universidad de Chile, Facultad de Ciencias Fisicas y Matematicas, Beaucheff 850, Santiago (Chile)], E-mail: mmoroni@ing.uchile.cl; Sepulveda, Aquiles [Universidad de Chile, Facultad de Ciencias Fisicas y Matematicas, Beaucheff 850, Santiago (Chile)

    2008-11-25

    This study evaluates the properties of a superelastic CuAlBe shape memory alloy under cyclic loading to assess its potential for applications in seismic resistant design. Wires {phi} = 0.5 mm, previously heated during different periods of time, are tested to study the effect of grain size, temperature and strain rate on the strength, equivalent viscous damping, and recentering properties of the alloy. The wires are subjected to quasi-static and dynamic tensile loading tests. The results show that nearly ideal superelastic properties can be obtained up to 3% axial strain. Overall, the damping potential of the alloy is moderate, typically less than 5%. Increased temperatures lead to a reduction in the equivalent damping and an increase in the forward transformation stress, and increased grain sizes lead to an increase in the equivalent damping and a reduction in the forward transformation and ultimate stresses.

  9. 10,000-Hour Cyclic Oxidation Behavior at 982 C (1800 F) of 68 High-Temperature Co-, Fe-, and Ni-Base Alloys

    Science.gov (United States)

    Barrett, Charles A.

    1997-01-01

    Sixty-eight high temperature Co-, Fe-, and Ni-base alloys were tested for 10-one thousand hour cycles in static air at 982 C (1800 F). The oxidation behavior of the test samples was evaluated by specific weight change/time data, x-ray diffraction of the post-test samples, and their final appearance. The gravimetric and appearance data were combined into a single modified oxidation parameter, KB4 to rank the cyclic oxidation resistance from excellent to catastrophic. The alloys showing the 'best' resistance with no significant oxidation attack were the alumina/aluminate spinel forming Ni-base turbine alloys: U-700, NASA-VIA and B-1900; the Fe-base ferritic alloys with Al: TRW-Valve, HOS-875, NASA-18T, Thermenol and 18SR; and the Ni-base superalloy IN-702.

  10. Effects of Cyclic Loading on Mechanical Behavior of 24S-T4 and 75S-T6 Aluminum Alloys and SAE 4130 Steel

    Science.gov (United States)

    Macgregor, C W; Grossman, N

    1952-01-01

    An investigation was conducted to determine the effects of cyclic loading on the mechanical behavior of 24S-T4 and 75S-T6 aluminum alloys and SAE 4130 steel. Specimens of the three materials were subjected to various numbers of prior fatigue cycles both below and above the fatigue limits. Special slow-bend tests were employed to show the effects of prior cycles of fatigue stressing on the transition temperature to brittle fracture for SAE 4130 steel and on the energy-absorption capacity of the aluminum alloys. Micrographic studies were made to observe and measure crack formation and propagation and additional special tests were conducted to supplement the results of the slow-bend tests. These included Charpy impact tests, mirohardness surveys, tension tests, and fretting-corrosion studies.

  11. Cyclic Vitalism

    DEFF Research Database (Denmark)

    Halse, Sven

    2014-01-01

    an enthusiastic worshipping of life, one that holds youth, health, strength and beauty as its primary attributes, and which was prevalent in all aspects of cultural life around 1900. But even the post war founders of the Vitalist re-conceptualisation of this era, Wolfdietrich Rasch and Gunter Martens, warned...... that also encompasses notions of destruction, decay and death. “All life symbols in literature around 1900 are at the same time symbols of death”. (Rasch, W. 1967:24) Through the analyses of three poems, this article aims to show concrete examples of how cyclic Vitalist thinking is embedded in poetry...

  12. Phase Transformation Behavior and Resistance to Bending and Cyclic Fatigue of ProTaper Gold and ProTaper Universal Instruments.

    Science.gov (United States)

    Hieawy, Ahmed; Haapasalo, Markus; Zhou, Huimin; Wang, Zhe-Jun; Shen, Ya

    2015-07-01

    The purpose of this study was to compare the flexibility and cyclic fatigue resistance of ProTaper Universal (PTU; Dentsply Tulsa Dental Specialities, Tulsa, OK) and ProTaper Gold (PTG; Dentsply Tulsa Dental Specialities, Tulsa, OK) instruments in relation to their phase transformation behavior. Sizes S1, S2, F1, F2, and F3 of PTU and PTG instruments were subjected to rotational bending at a curvature of 40° and a radius of 6 mm. The number of cycles to fracture (NCF) was recorded. The fracture surface of all fragments was examined with a scanning electron microscope. Flexibility was determined by 45° bending tests according to the ISO 3630-1 specification. Unused and fractured instruments were examined by differential scanning calorimetry. PTG had a cyclic fatigue resistance superior to PTU in all sizes (P difference in the NCF of PTU instruments was detected between F1 and F2. The fractured files of both PTU and PTG showed the typical fracture pattern of fatigue failure. The bending load values were significantly lower for PTG than for PTU (P difference in the austenite finish between unused files and instruments subjected to the fatigue process. PTG files were significantly more flexible and resistant to fatigue than PTU files. PTG exhibited different phase transformation behavior than PTU, which may be attributed to the special heat treatment history of PTG instruments. PTG may be more suited for preparing canals with a more abrupt curvature. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  13. Thermal-hydraulic behaviors of vapor-liquid interface due to arrival of a pressure wave

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Akira; Fujii, Yoshifumi; Matsuzaki, Mitsuo [Tokyo Institute of Technology (Japan)

    1995-09-01

    In the vapor explosion, a pressure wave (shock wave) plays a fundamental role for triggering, propagation and enhancement of the explosion. Energy of the explosion is related to the magnitude of heat transfer rate from hot liquid to cold volatile one. This is related to an increasing rate of interface area and to an amount of transient heat flux between the liquids. In this study, the characteristics of transient heat transfer and behaviors of vapor film both on the platinum tube and on the hot melt tin drop, under same boundary conditions have been investigated. It is considered that there exists a fundamental mechanism of the explosion in the initial expansion process of the hot liquid drop immediately after arrival of pressure wave. The growth rate of the vapor film is much faster on the hot liquid than that on the solid surface. Two kinds of roughness were observed, one due to the Taylor instability, by rapid growth of the explosion bubble, and another, nucleation sites were observed at the vapor-liquid interface. Based on detailed observation of early stage interface behaviors after arrival of a pressure wave, the thermal fragmentation mechanism is proposed.

  14. CHF Phenomena by Photographic Study of Boiling Behavior due to Transient Heat Inputs

    Directory of Open Access Journals (Sweden)

    Jongdoc Park

    2012-01-01

    Full Text Available The transient boiling heat transfer characteristics in a pool of water and highly wetting liquids such as ethanol and FC-72 due to an exponentially increasing heat input of various rates were investigated using the 1.0 mm diameter experimental heater shaped in a horizontal cylinder for wide ranges of pressure and subcooling. The trend of critical heat flux (CHF values in relation to the periods was divided into three groups. The CHF belonging to the 1st group with a longer period occurs with a fully developed nucleate boiling (FDNB heat transfer process. For the 2nd group with shorter periods, the direct transition to film boiling from non boiling occurs as an explosive boiling. The direct boiling transition at the CHF from non-boiling regime to film boiling occurred without a heat flux increase. It was confirmed that the initial boiling behavior is significantly affected by the property and the wettability of the liquid. The photographic observations on the vapor bubble behavior during transitions to film boiling were performed using a high-speed video camera system.

  15. The arabidopsis cyclic nucleotide interactome

    KAUST Repository

    Donaldson, Lara

    2016-05-11

    Background Cyclic nucleotides have been shown to play important signaling roles in many physiological processes in plants including photosynthesis and defence. Despite this, little is known about cyclic nucleotide-dependent signaling mechanisms in plants since the downstream target proteins remain unknown. This is largely due to the fact that bioinformatics searches fail to identify plant homologs of protein kinases and phosphodiesterases that are the main targets of cyclic nucleotides in animals. Methods An affinity purification technique was used to identify cyclic nucleotide binding proteins in Arabidopsis thaliana. The identified proteins were subjected to a computational analysis that included a sequence, transcriptional co-expression and functional annotation analysis in order to assess their potential role in plant cyclic nucleotide signaling. Results A total of twelve cyclic nucleotide binding proteins were identified experimentally including key enzymes in the Calvin cycle and photorespiration pathway. Importantly, eight of the twelve proteins were shown to contain putative cyclic nucleotide binding domains. Moreover, the identified proteins are post-translationally modified by nitric oxide, transcriptionally co-expressed and annotated to function in hydrogen peroxide signaling and the defence response. The activity of one of these proteins, GLYGOLATE OXIDASE 1, a photorespiratory enzyme that produces hydrogen peroxide in response to Pseudomonas, was shown to be repressed by a combination of cGMP and nitric oxide treatment. Conclusions We propose that the identified proteins function together as points of cross-talk between cyclic nucleotide, nitric oxide and reactive oxygen species signaling during the defence response.

  16. Hybrids of HNBR and in situ polymerizable cyclic butylene terephthalate (CBT oligomers: properties and dry sliding behavior

    Directory of Open Access Journals (Sweden)

    2008-07-01

    Full Text Available A peroxide curable hydrogenated nitrile rubber (HNBR was modified by cyclic butylene terephthalate oligomer (CBT, added in 100 parts per hundred rubber (phr. CBT polymerization was expected to occur simultaneously with that of the curing of the HNBR rubber (T = 190°C, t = 25 min. Differential scanning calorimetry (DSC indicated that only a minor part of CBT has been polymerized (pCBT in the hybrid. Dynamic mechanical thermal analysis (DMTA revealed that HNBR formed the continuous whereas (pCBT the dispersed phase. Mechanical properties (hardness, tensile modulus, ultimate tensile strength and strain, tear strength of the HNBR and HNBR/CBT were determined and collated. Tribological properties were investigated with pin(steel-onplate(rubber (POP, with roller(steel-on-plate (rubber (ROP, with oscillating steel cylinder on rubber plate (Fretting test configurations. Coefficient of friction (COF and specific wear rate of the HNBR-based systems were determined. It was found that the resistance to wear increases with CBT hybridization. On the other hand, COF did not change much with CBT content. The friction and wear characteristics strongly depended on the test configurations. The worn surface of the HNBR systems was inspected in scanning electron microscope (SEM to conclude the typical wear mechanisms. SEM investigation showed that the CBT was predominantly recrystallized from its molten state under the curing conditions set. The well developed prism- and platy-like, micron-scaled CBT crystals were made responsible for the reinforcing effect observed.

  17. Voltammetric behavior, biocidal effect and synthesis of some new nanomeric fused cyclic thiosemicarbazones and their mercuric(II salts

    Directory of Open Access Journals (Sweden)

    M.S.T. Makki

    2014-11-01

    Full Text Available New nanomeric 3-thioxo-5-methoxy-4,5-dihydro-6-methyl-9-unsubstituted/substituted-1,2,4-triazino[5,6-b]indoles (2a–c and 3-thioxo-5-methoxy-4,5-dihydro-6,7-dihydroxy-1,2,4-triaino[5,6]-cyclobut-6-ene (3 were prepared via reaction of thiosemicarbazide with 5-unsubstitutedand/substituted-indol-2,3-diones and/or 3,4-dihydroxycyclobutane-1,2-dione in methanol–concentrated HCl at room temperature. A series of mercury(II–ligand salts e.g. compound 4b and Hg(II complexes 5a,b and 6 of cyclic Schiff base were prepared. Structures of these compounds were established by elemental analysis and spectral measurements. The redox characteristics of selected compounds were studied for use as chelating agents for stripping voltammetric determination of mercuric(II ions in aqueous media. The compounds were also screened for their use as molluscicidal agents against Biomophalaria Alexandrina Snails responsible for Bilhariziasis.

  18. Molecular Dynamics Simulations on the Behaviors of Hydrophilic/Hydrophobic Cyclic Peptide Nanotubes at the Water/Hexane Interface.

    Science.gov (United States)

    Lin, Huifang; Fan, Jianfen; Weng, Peipei; Si, Xialan; Zhao, Xin

    2017-09-08

    In this work, nine kinds of amino acid residues, i.e., alanine (A), leucine (L), valine (V), isoleucine (I), tryptophan (W), glutamine (Q), threonine (T), serine (S), and cysteine (C), were selected to construct seven cyclic peptide nanotubes (CPNTs) with diverse hydrophilic/hydrophobic external surfaces, which were further separately inserted at the water/hexane interface to investigate their microstructures and interfacial properties. Molecular dynamics (MD) simulations reveal that all the CPNTs except the QT- and VL-CPNTs have different degrees of tilt, fracture, and shedding at the interface. The end-CPs are more susceptible to the effect of the surroundings than the mid-CPs. The interactions of individual CP subunits with the neighborings disclose the firmness of the mid-CPs and the dissociation of the end-CPs. The results indicate that a hydrophobic CPNT is prone to stay at the interface, while a hydrophilic CPNT easily enters the water phase, resulting in many H-bonds with water. Results in this work enrich the dynamic properties of a hydrophilic/hydrophobic CPNT at the biphase interface at the atomic level.

  19. Diffusional transport during the cyclic oxidation of gamma + beta, Ni-Cr-Al(Y, Zr) alloys

    Science.gov (United States)

    Nesbitt, J. A.; Heckel, R. W.

    1988-01-01

    The cyclic oxidation behavior of several cast gamma + beta, Ni-Cr-Al(Y, Zr) alloys and one low-pressure plasma spraying gamma + beta, Ni-Co-Cr-Al(Y) alloy was studied. Cyclic oxidation was found to result in a decreasing Al concentration at the oxide-metal interface due to a high rate of Al consumption coupled with oxide scale cracking and spalling. Diffusion paths plotted on the ternary phase diagram showed higher Ni concentrations with increasing cyclic oxidation exposures. The alloy with the highest rate of Al consumption and the highest Al content underwent breakaway oxidation following 500 1-hr cycles at 1200 C.

  20. Diffusional transport during the cyclic oxidation of gamma + beta, Ni-Cr-Al(Y, Zr) alloys

    Science.gov (United States)

    Nesbitt, J. A.; Heckel, R. W.

    1988-01-01

    The cyclic oxidation behavior of several cast gamma + beta, Ni-Cr-Al(Y, Zr) alloys and one low-pressure plasma spraying gamma + beta, Ni-Co-Cr-Al(Y) alloy was studied. Cyclic oxidation was found to result in a decreasing Al concentration at the oxide-metal interface due to a high rate of Al consumption coupled with oxide scale cracking and spalling. Diffusion paths plotted on the ternary phase diagram showed higher Ni concentrations with increasing cyclic oxidation exposures. The alloy with the highest rate of Al consumption and the highest Al content underwent breakaway oxidation following 500 1-hr cycles at 1200 C.

  1. Cyclic Vitalism

    DEFF Research Database (Denmark)

    Halse, Sven

    2014-01-01

    of taking such a unilateral view of what constituted a Vitalist concept of life. It could lead to a misunderstanding of Vitalist way of thinking, Rasch said, if the focus were only set upon the enthusiastic surplus, the worshipping of youth and health. To Vitalists, life is more than that. It is a totality...... that also encompasses notions of destruction, decay and death. “All life symbols in literature around 1900 are at the same time symbols of death”. (Rasch, W. 1967:24) Through the analyses of three poems, this article aims to show concrete examples of how cyclic Vitalist thinking is embedded in poetry...... of the era. The analyses include a further sub-categorisation to capture the different types of Life Force dealt with in the texts. By way of an introduction, Vitalism is discussed within the context of the scientific and social developments of the 19th Century....

  2. The cyclic nucleotide gated channel subunit CNG-1 instructs behavioral outputs in Caenorhabditis elegans by coincidence detection of nutritional status and olfactory input.

    Science.gov (United States)

    He, Chao; Altshuler-Keylin, Svetlana; Daniel, David; L'Etoile, Noelle D; O'Halloran, Damien

    2016-10-06

    In mammals, olfactory subsystems have been shown to express seven-transmembrane G-protein-coupled receptors (GPCRs) in a one-receptor-one-neuron pattern, whereas in Caenorhabditis elegans, olfactory sensory neurons express multiple G-protein coupled odorant receptors per olfactory sensory neuron. In both mammalian and C. elegans olfactory sensory neurons (OSNs), the process of olfactory adaptation begins within the OSN; this process of negative feedback within the mammalian OSN has been well described in mammals and enables activated OSNs to desensitize their response cell autonomously while attending to odors detected by separate OSNs. However, the mechanism that enables C. elegans to adapt to one odor and attend to another odor sensed by the same olfactory sensory neuron remains unclear. We found that the cyclic nucleotide gated channel subunit CNG-1 is required to promote cross adaptation responses between distinct olfactory cues. This change in sensitivity to a pair of odorants after persistent stimulation by just one of these odors is modulated by the internal nutritional state of the animal, and we find that this response is maintained across a diverse range of food sources for C. elegans. We also reveal that CNG-1 integrates food related cues for exploratory motor output, revealing that CNG-1 functions in multiple capacities to link nutritional information with behavioral output. Our data describes a novel model whereby CNG channels can integrate the coincidence detection of appetitive and olfactory information to set olfactory preferences and instruct behavioral outputs.

  3. Study the Cyclic Plasticity Behavior of 508 LAS under Constant, Variable and Grid-Load-Following Loading Cycles for Fatigue Evaluation of PWR Components

    Energy Technology Data Exchange (ETDEWEB)

    Mohanty, Subhasish [Argonne National Lab. (ANL), Argonne, IL (United States); Barua, Bipul [Argonne National Lab. (ANL), Argonne, IL (United States); Soppet, William K. [Argonne National Lab. (ANL), Argonne, IL (United States); Majumdar, Saurin [Argonne National Lab. (ANL), Argonne, IL (United States); Natesan, Ken [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-09-01

    This report provides an update of an earlier assessment of environmentally assisted fatigue for components in light water reactors. This report is a deliverable in September 2016 under the work package for environmentally assisted fatigue under DOE’s Light Water Reactor Sustainability program. In an April 2016 report, we presented a detailed thermal-mechanical stress analysis model for simulating the stress-strain state of a reactor pressure vessel and its nozzles under grid-load-following conditions. In this report, we provide stress-controlled fatigue test data for 508 LAS base metal alloy under different loading amplitudes (constant, variable, and random grid-load-following) and environmental conditions (in air or pressurized water reactor coolant water at 300°C). Also presented is a cyclic plasticity-based analytical model that can simultaneously capture the amplitude and time dependency of the component behavior under fatigue loading. Results related to both amplitude-dependent and amplitude-independent parameters are presented. The validation results for the analytical/mechanistic model are discussed. This report provides guidance for estimating time-dependent, amplitude-independent parameters related to material behavior under different service conditions. The developed mechanistic models and the reported material parameters can be used to conduct more accurate fatigue and ratcheting evaluation of reactor components.

  4. Data related to cyclic deformation and fatigue behavior of direct laser deposited Ti-6Al-4V with and without heat treatment.

    Science.gov (United States)

    Sterling, Amanda J; Torries, Brian; Shamsaei, Nima; Thompson, Scott M

    2016-03-01

    Data is presented describing the strain-controlled, fully-reversed uniaxial cyclic deformation and fatigue behavior of Ti-6Al-4V specimens additively manufactured via Laser Engineered Net Shaping (LENS) - a Direct Laser Deposition (DLD) process. The data was collected by performing multiple fatigue tests on specimens with various microstructural states/conditions, i.e. in their 'as-built', annealed (below the beta transus temperature), or heat treated (above the beta transus temperature) condition. Such data aids in characterizing the mechanical integrity and fatigue resistance of DLD parts. Data presented herein also allows for elucidating the strong microstructure coupling of the fatigue behavior of DLD Ti-6Al-4V, as the data trends were found to vary with material condition (i.e. as-built, annealed or heat treated) [1]. This data is of interest to the additive manufacturing and fatigue scientific communities, as well as the aerospace and biomedical industries, since additively-manufactured parts cannot be reliably deployed for public use, until their mechanical properties are understood with high certainty.

  5. Data related to cyclic deformation and fatigue behavior of direct laser deposited Ti–6Al–4V with and without heat treatment

    Directory of Open Access Journals (Sweden)

    Amanda J. Sterling

    2016-03-01

    Full Text Available Data is presented describing the strain-controlled, fully-reversed uniaxial cyclic deformation and fatigue behavior of Ti–6Al–4V specimens additively manufactured via Laser Engineered Net Shaping (LENS – a Direct Laser Deposition (DLD process. The data was collected by performing multiple fatigue tests on specimens with various microstructural states/conditions, i.e. in their ‘as-built’, annealed (below the beta transus temperature, or heat treated (above the beta transus temperature condition. Such data aids in characterizing the mechanical integrity and fatigue resistance of DLD parts. Data presented herein also allows for elucidating the strong microstructure coupling of the fatigue behavior of DLD Ti–6Al–4V, as the data trends were found to vary with material condition (i.e. as-built, annealed or heat treated [1]. This data is of interest to the additive manufacturing and fatigue scientific communities, as well as the aerospace and biomedical industries, since additively-manufactured parts cannot be reliably deployed for public use, until their mechanical properties are understood with high certainty.

  6. Heat-mechanics interaction behavior of lead rubber bearings for seismic base isolation under large and cyclic lateral deformation. Part 1. Dynamic loading test of LRB and development of analytical method

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, Akihiro; Takenaka, Yasuo; Takaoka, Eiji; Hikita, Makiko; Hyodo, Yo (Kajima Corporation, Tokyo (Japan)), e-mail: kondo-akihiro@kajima.com; Kitamura, Haruyuki (Tokyo Univ. of Science, Chiba (Japan)), e-mail: kita-h@rs.noda.tus.ac.jp

    2009-07-01

    When base-isolated buildings are subjected to long-period strong earthquakes emanating from oceanic trenches, base-isolation devices such as Lead Rubber Bearings (LRB) can be subjected to larger and more cyclic deformations than anticipated in structural design. In an LRB, seismic input energy is absorbed as hysteresis energy of a lead plug, and finally transformed into thermal energy. The resulting large and multiple cyclic deformations of the LRB generate a large amount of heat, causing high temperatures of the lead plug. The resulting deterioration of damping characteristics which encompasses a complex thermal and mechanical phenomenon provides a serious concern for the base-isolated building responses. However, there is insufficient experimental data on this phenomenon, and no analytical method for evaluation of heat-mechanics interaction behavior has been derived. The paper describes experimental results and derivation of analytical methods for determining the heat-mechanics interaction of the LRB under a large and cyclic lateral deformation

  7. Cyclic adenosine monophosphate metabolism in synaptic growth, strength, and precision: neural and behavioral phenotype-specific counterbalancing effects between dnc phosphodiesterase and rut adenylyl cyclase mutations.

    Science.gov (United States)

    Ueda, Atsushi; Wu, Chun-Fang

    2012-03-01

    Two classic learning mutants in Drosophila, rutabaga (rut) and dunce (dnc), are defective in cyclic adenosine monophosphate (cAMP) synthesis and degradation, respectively, exhibiting a variety of neuronal and behavioral defects. We ask how the opposing effects of these mutations on cAMP levels modify subsets of phenotypes, and whether any specific phenotypes could be ameliorated by biochemical counter balancing effects in dnc rut double mutants. Our study at larval neuromuscular junctions (NMJs) demonstrates that dnc mutations caused severe defects in nerve terminal morphology, characterized by unusually large synaptic boutons and aberrant innervation patterns. Interestingly, a counterbalancing effect led to rescue of the aberrant innervation patterns but the enlarged boutons in dnc rut double mutant remained as extreme as those in dnc. In contrast to dnc, rut mutations strongly affect synaptic transmission. Focal loose-patch recording data accumulated over 4 years suggest that synaptic currents in rut boutons were characterized by unusually large temporal dispersion and a seasonal variation in the amount of transmitter release, with diminished synaptic currents in summer months. Experiments with different rearing temperatures revealed that high temperature (29-30°C) decreased synaptic transmission in rut, but did not alter dnc and wild-type (WT). Importantly, the large temporal dispersion and abnormal temperature dependence of synaptic transmission, characteristic of rut, still persisted in dnc rut double mutants. To interpret these results in a proper perspective, we reviewed previously documented differential effects of dnc and rut mutations and their genetic interactions in double mutants on a variety of physiological and behavioral phenotypes. The cases of rescue in double mutants are associated with gradual developmental and maintenance processes whereas many behavioral and physiological manifestations on faster time scales could not be rescued. We discuss

  8. Differences in structure and magnetic behavior of Mn-AlN films due to substrate material

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Takanobu; Nakatani, Ryoichi [Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University (Japan); Endo, Yasushi [Depertment of Electrical and Communication Engineering, Graduate School of Engineering, Tohoku University (Japan); Kirino, Fumiyoshi [Conservation of Cultural Property, Graduate School of Fine Arts, Tokyo National University of Fine Arts and Music (Japan)], E-mail: takanobu.sato@mat.eng.osaka-u.ac.jp

    2009-05-01

    The structure and magnetic behavior of Mn-AlN (Al{sub 1-x}Mn{sub x}N, x = 0.03, 0.04) films deposited on thermally oxidized Si (001) substrates and sapphire (0001) substrates were studied. Mn-AlN films deposited on each substrate had a wuertzite-type AlN phase with a preferentially oriented c-axis. Mn-AlN films that were deposited on Si (001) substrate exhibited paramagnetic behavior. In addition to paramagnetic behavior, weak ferromagnetic behavior with curie temperatures higher than room temperature were observed for Mn-AlN films deposited on sapphire (0001) substrates.

  9. Comparison of Cyclic Hysteresis Behavior between Cross-Ply C/SiC and SiC/SiC Ceramic-Matrix Composites

    Directory of Open Access Journals (Sweden)

    Longbiao Li

    2016-01-01

    Full Text Available In this paper, the comparison of cyclic hysteresis behavior between cross-ply C/SiC and SiC/SiC ceramic-matrix composites (CMCs has been investigated. The interface slip between fibers and the matrix existed in the matrix cracking mode 3 and mode 5, in which matrix cracking and interface debonding occurred in the 0° plies are considered as the major reason for hysteresis loops of cross-ply CMCs. The hysteresis loops of cross-ply C/SiC and SiC/SiC composites corresponding to different peak stresses have been predicted using present analysis. The damage parameter, i.e., the proportion of matrix cracking mode 3 in the entire matrix cracking modes of the composite, and the hysteresis dissipated energy increase with increasing peak stress. The damage parameter and hysteresis dissipated energy of C/SiC composite under low peak stress are higher than that of SiC/SiC composite; However, at high peak stress, the damage extent inside of cross-ply SiC/SiC composite is higher than that of C/SiC composite as more transverse cracks and matrix cracks connect together.

  10. Potential-dependent adsorption/desorption behavior of perfluorosulfonated ionomer on a gold electrode surface studied by cyclic voltammetry, electrochemical quartz microbalance, and electrochemical atomic force microscopy.

    Science.gov (United States)

    Masuda, Takuya; Ikeda, Kota; Uosaki, Kohei

    2013-02-19

    Potential-dependent adsorption/desorption behavior of perfluorosulfonated ionomer (PFSI) on a gold electrode was investigated by cyclic voltammetry (CV), electrochemical quartz crystal microbalance (EQCM), and electrochemical atomic force microscopy (EC-AFM) in a Nafion (i.e., PFSI) dispersed aqueous solution without any other electrolyte. It was found that PFSI serves as an electrolyte and that electrochemical measurements can be performed in this solution without any significant IR drop. PFSI molecules were adsorbed on the Au surface in the lying-down configuration in the potential range between 0 and 0.45 V, the amount of adsorbed PFSI increased when the potential was made more positive than 0.75 V, and the adsorbed PFSI fully desorbed from the surface at potentials more positive than 1.4 V where gold oxide was formed. Once the gold oxide had been reduced, PFSI readsorbed on the surface, albeit slowly. PFSI desorbed from the surface as the potential was made more negative than 0 V. These processes took place reversibly.

  11. Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats

    Science.gov (United States)

    Qian, Jie; Mummalaneni, Shobha; Phan, Tam-Hao T.; Heck, Gerard L.; DeSimone, John A.; West, David; Mahavadi, Sunila; Hojati, Deanna; Murthy, Karnam S.; Rhyu, Mee-Ra; Spielman, Andrew I.; Özdener, Mehmet Hakan

    2017-01-01

    During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells (TRCs). Currently, the intracellular signals that regulate the postnatal development of salt taste have not been identified. We investigated the effect of cAMP, a downstream signal for arginine vasopressin (AVP) action, on the postnatal development of NaCl responses in 19–23 day old rats. ENaC-dependent NaCl CT responses were monitored after lingual application of 8-chlorophenylthio-cAMP (8-CPT-cAMP) under open-circuit conditions and under ±60 mV lingual voltage clamp. Behavioral responses were tested using 2 bottle/24h NaCl preference tests. The effect of [deamino-Cys1, D-Arg8]-vasopressin (dDAVP, a specific V2R agonist) was investigated on ENaC subunit trafficking in rat FF TRCs and on cAMP generation in cultured adult human FF taste cells (HBO cells). Our results show that in 19–23 day old rats, the ENaC-dependent maximum NaCl CT response was a saturating sigmoidal function of 8-CPT-cAMP concentration. 8-CPT-cAMP increased the voltage-sensitivity of the NaCl CT response and the apical Na+ response conductance. Intravenous injections of dDAVP increased ENaC expression and γ-ENaC trafficking from cytosolic compartment to the apical compartment in rat FF TRCs. In HBO cells dDAVP increased intracellular cAMP and cAMP increased trafficking of γ- and δ-ENaC from cytosolic compartment to the apical compartment 10 min post-cAMP treatment. Control 19–23 day old rats were indifferent to NaCl, but showed clear preference for appetitive NaCl concentrations after 8-CPT-cAMP treatment. Relative to adult rats, 14 day old rats demonstrated significantly less V2R antibody binding in circumvallate TRCs. We conclude that an age-dependent increase in V2R expression produces an AVP-induced incremental increase in cAMP that

  12. Behavioral sexual dimorphism in models of anxiety and depression due to changes in HPA axis activity.

    Science.gov (United States)

    Kokras, Nikolaos; Dalla, Christina; Sideris, Antonios C; Dendi, Artemis; Mikail, Hudu G; Antoniou, Katerina; Papadopoulou-Daifoti, Zeta

    2012-01-01

    Anxiety and depression are considered as stress-related disorders, which present considerable sex differentiation. In animal models of anxiety and depression sex differences have been described and linked to the sexually dimorphic hypothalamus-pituitary-adrenals (HPA) axis. The present study aimed to adjust corticosterone, the main HPA axis stress hormone, in male and female adrenalectomized rats with oral (25 μg/ml) corticosterone replacement (ADXR). Subsequently we investigated the behavioral performance of ADXR rats in the open field, light/dark and forced swim test (FST). Male ADXR rats showed less anxiety-like behavior when compared to sham-operated controls, despite adequate corticosterone replacement. They further showed increased swimming and reduced climbing behavior in the FST, while immobility duration did not differ from sham-operated males. On the contrary, adrenalectomy and corticosterone replacement did not have significant effects on the female behavioral response. Females were generally more active and presented less anxiety-like behavior than males, while they exhibited higher depressive-like symptomatology in the FST. ADXR affected behavioral responses predominantly in males, which in turn modified sex differences in the behavioral profile. Females in proestrous and estrous did not differ from females in diestrous and methestrous in any measured behavioral response. Present results suggest that the male and not the female behavioral responses in models of anxiety and depression were mainly affected by ADXR. These findings may play a significant role in explaining the differential coping strategy of the two sexes in response to stressful experiences. This article is part of a Special Issue entitled 'Anxiety and Depression'.

  13. Moment Contribution Capacity of Tendon Prestressed Partial on Concrete Beam-column Joint Interior According to Provisions ACI 318-2008 Chapter 21.5.2.5(c Due to Cyclic Lateral Loads

    Directory of Open Access Journals (Sweden)

    Astawa Made Dharma

    2016-01-01

    Full Text Available This research designed a partial prestressed concrete beam-column with reinforced concrete interior joint, using square columns of 400/400 mm, reinforcement 6 D16 + 4D13, section beam 250/400 mm, tensile reinforcement 5 D13, compression reinforcement 3 D13 + 2 strand tendon D12,7 mm , and joint without plastic hinge, then tested in laboratory with lateral cyclic loads on peak column, static axial load 1120 kN on the centre column, to get the tendon capacity to assume positive and negative bending moments due to lateral load, according to provisions of ACI 318-2008 part 21.5.2.5 (c. Test results showed that the moment tendon contribution on beam section, in the tensile area, the positive and negative moment both on the left side or the right side column are all qualified ( 25 %. As for the negative moment, either left or right side column are all qualified (4.0. Although the contribution of positive moment capacity tendon in compression areas does not qualify, in overall, the reliability and ductility of the structure qualify.

  14. Abnormal Nocturnal Behavior due to Hypoglycemia in a Patient with Type 2 Diabetes.

    Science.gov (United States)

    Yang, Kwang Ik; Kim, Hyung Ki; Baek, Jeehun; Kim, Doh-Eui; Park, Hyung Kook

    2016-04-15

    Abnormal nocturnal behavior can have many causes, including primary sleep disorder, nocturnal seizures, and underlying medical or neurological disorders. A 79-year-old woman with type 2 diabetes was admitted for evaluation of abnormal nocturnal behavior. Every night at around 04:30 she was observed displaying abnormal behavior including leg shaking, fumbling with bedclothes, crawling around the room with her eyes closed, and non-responsiveness to verbal communication. Polysomnography with 20-channel electroencephalography (EEG) was performed. EEG showed that the posterior dominant rhythm was slower than that observed in the initial EEG, with diffuse theta and delta activities intermixed, and no epileptiform activity. The serum glucose level was 35 mg/dL at that time, and both the EEG findings and clinical symptoms were resolved after an intravenous injection of 50 mL of 50% glucose. These results indicate that nocturnal hypoglycemia should be considered as one of the possible etiologies in patients presenting with abnormal nocturnal behavior.

  15. A Mechanism Facilitates Pollination due to Stigma Behavior in Campsis radicans (Bignoniaceae)

    Institute of Scientific and Technical Information of China (English)

    YANGShu-Xiang; YANGChun-Feng; ZHANGTao; WANGQing-Feng

    2004-01-01

    The precise factors affecting stigma behavior in Campsis radicans (L.) Seem. ex Bureau. remain unclear up to now. In this study mechanical touch, self- and cross-pollination, and pollination with variable amounts of pollen grains separately contacting with stigmas have been conducted to determine the exact factor affecting the stigma behavior. Results show that mechanical touch alone cannot make the stigmas close permanently. It is the adequate pollen (>350) deposition that causes the stigma permanent closure, which is in accordance with previous reports that sufficient pollen grains are necessary for fruit development. In addition, the stigma behavior does not display differences when pollinated with cross- or self-pollen separately; both self and cross pollen grains can germinate and grow successfully. Our results cannot demonstrate that the stigma behavior in C. radicans is an outcrossing mechanism, but strongly indicate it acts as a mechanism to facilitate pollination, and then enhance the reproductive success.

  16. The Effect of Cognitive Behavior Therapy in Insomnia due to Methadone Maintenance Therapy: A Randomized Clinical Trial

    OpenAIRE

    Robabeh Soleimani; Mohammad Jafar Modabbernia; Sharareh Habibi; Maryam Habibi Roudsary; Masoumeh Elahi

    2015-01-01

    Background: Sleep disturbance is a common complaint of patients undergoing methadone maintenance therapy (MMT). There are limited studies about the effect of different treatments on insomnia due to MMT. In this study, we evaluated the effect of cognitive-behavioral treatment for insomnia (CBTI) on sleep disorders in patients undergoing MMT. Methods: Twenty-two patients with insomnia due to MMT (aged 18-60 years) participated in this randomized double-blind clinical trial. The intervention ...

  17. Trial-to-trial reoptimization of motor behavior due to changes in task demands is limited.

    Directory of Open Access Journals (Sweden)

    Orban de Xivry J-J

    Full Text Available Each task requires a specific motor behavior that is tuned to task demands. For instance, writing requires a lot of accuracy while clapping does not. It is known that the brain adjusts the motor behavior to different task demands as predicted by optimal control theory. In this study, the mechanism of this reoptimization process is investigated by varying the accuracy demands of a reaching task. In this task, the width of the reaching target (0.5 or 8 cm was varied either on a trial-to-trial basis (random schedule or in blocks (blocked schedule. On some trials, the hand of the subjects was clamped to a rectilinear trajectory that ended 2 cm on the left or right of the target center. The rejection of this perturbation largely varied with target width in the blocked schedule but not in the random schedule. That is, subjects exhibited different motor behavior in the different schedules despite identical accuracy demands. Therefore, while reoptimization has been considered immediate and automatic, the differences in motor behavior observed across schedules suggest that the reoptimization of the motor behavior is neither happening on a trial-by-trial basis nor obligatory. The absence of trial-to-trial mechanisms, the inability of the brain to adapt to two conflicting task demands and the existence of a switching cost are discussed as possible sources of the non-optimality of motor behavior during the random schedule.

  18. Analysis of uniaxial behavior of an Fe-based shape memory alloy under cyclic thermomechanical loading; Netsu rikigakuteki kurikaeshi fuka no moto deno tetsuki keijo kioku gokin no tanjiku henkei/hentai kyodo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Nishimura, F.; Watanabe, N.; Tanaka, K. [Tokyo Metropolitan Institute of Technology, Tokyo (Japan)

    1997-08-15

    The thermomechanical hysteretic behavior of an Fe-based shape memory alloy is phenomenologically analyzed under cyclic uniaxial tensile and compressive loading. The shift of the stress-strain-temperature hysteresis loop, expressed by means of the evolution of the residual strain, is well explained by the theory with some internal variables. The accumulated perfect dislocations formed as a result of the interaction of martensite plates is one of the internal variables introduced here. The back stress is also employed as an internal variable to be the driving force for the shape recovery for the martensite plates. The simulations describe well the hysteretic behavior under the strain and stress-controlled cyclic thermomechanical loading; the shift of a loop, evolution of the residual strain and the change in transformation stress. 21 refs., 10 figs., 1 tab.

  19. 1,4-Di-N-oxide quinoxaline-2-carboxamide: Cyclic voltammetry and relationship between electrochemical behavior, structure and anti-tuberculosis activity

    OpenAIRE

    Moreno-Viguri, E. (Elsa); Perez-Silanes, S. (Silvia); Gouravaram, S. (S.); Macharam, A. (Abinav); Ancizu, S. (Saioa); Torres, E; Aldana, I.; Monge, A; Crawford, P.W. (Philip W.)

    2011-01-01

    To gain insight into the mechanism of action, the redox properties of 37 quinoxaline-2-carboxamide 1,4-di-N-oxides with varying degrees of anti-tuberculosis activity were studied in dimethylformamide (DMF) using cyclic voltammetry and first derivative cyclic voltammetry. For all compounds studied, electrochemical reduction in DMF is consistent with the reduction of the N-oxide functionality to form a radical anion. The influence of molecular structure on reduction potential is addressed and i...

  20. The Effects of Chiropractic Treatment on Students With Learning and Behavioral Impairments Due to Neurological Dysfunction.

    Science.gov (United States)

    Walton, E. V.; Brzozowski, Walter T.

    The effects of chiropractic treatment on children with learning and behavioral problems was investigated with 24 elementary and secondary level students, 12 receiving regular chiropractic treatment and 12 receiving medication. Results indicated that chiropractic treatment was more effective for the wide range symptoms common in the neurological…

  1. Cyclic Voltammetry And Linear Sweep Voltammetry Study Of Cyclic Tertiary Amines

    Institute of Scientific and Technical Information of China (English)

    ZHAO Ping; TIAN JinPing; YIN YingWu

    2001-01-01

    @@ Cyclic six membered a-aminonitrile have proved to be very versatile synthetic intermediates and have been widely used in the construction of a large number of indole alkaloids. In order to obtain some information about the mechanisn of electrochemical synthesis of aaminonitrile. Electrochemistry behaviors that include cyclic voltammetry and linear sweep voltammetry of cyclic tertiary amines which including N-benzylpiperidine (NBP), 1-(l-Methoxycarbonyl ethyl) piperidine (MCEP), N-methylcarbonylppiperidine (NMCP), Nethylpiperidine(NEP) was studied.

  2. Cyclic Voltammetry And Linear Sweep Voltammetry Study Of Cyclic Tertiary Amines

    Institute of Scientific and Technical Information of China (English)

    ZHAO; Ping

    2001-01-01

    Cyclic six membered a-aminonitrile have proved to be very versatile synthetic intermediates and have been widely used in the construction of a large number of indole alkaloids. In order to obtain some information about the mechanisn of electrochemical synthesis of aaminonitrile. Electrochemistry behaviors that include cyclic voltammetry and linear sweep voltammetry of cyclic tertiary amines which including N-benzylpiperidine (NBP), 1-(l-Methoxycarbonyl ethyl) piperidine (MCEP), N-methylcarbonylppiperidine (NMCP), Nethylpiperidine(NEP) was studied.……

  3. Neural correlates underlying naloxone-induced amelioration of sexual behavior deterioration due to an alarm pheromone

    Directory of Open Access Journals (Sweden)

    Tatsuya eKobayashi

    2015-02-01

    Full Text Available Sexual behavior is suppressed by various types of stressors. We previously demonstrated that an alarm pheromone released by stressed male Wistar rats is a stressor to other rats, increases the number of mounts needed for ejaculation, and decreases the hit rate (described as the number of intromissions/sum of the mounts and intromissions. This deterioration in sexual behavior was ameliorated by pretreatment with the opioid receptor antagonist naloxone. However, the neural mechanism underlying this remains to be elucidated. Here, we examined Fos expression in 31 brain regions of pheromone-exposed rats and naloxone-pretreated pheromone-exposed rats 60 min after 10 intromissions. As previously reported, the alarm pheromone increased the number of mounts and decreased the hit rate. In addition, Fos expression was increases in the anterior medial division, anterior lateral division and posterior division of the bed nucleus of the stria terminalis, parvocellular part of the paraventricular nucleus of the hypothalamus, arcuate nucleus, dorsolateral and ventrolateral periaqueductal gray, and nucleus paragigantocellularis. Fos expression decreased in the magnocellular part of the paraventricular nucleus of the hypothalamus. Pretreatment with naloxone blocked the pheromone-induced changes in Fos expression in the magnocellular part of the paraventricular nucleus of the hypothalamus, ventrolateral periaqueductal gray, and nucleus paragigantocellularis. Based on these results, we hypothesize that the alarm pheromone deteriorated sexual behavior by activating the ventrolateral periaqueductal gray-nucleus paragigantocellularis cluster and suppressing the magnocellular part of the paraventricular nucleus of the hypothalamus via the opioidergic pathway.

  4. Impact on behavioral changes due to chronic use of sertraline in Wistar albino rats

    Directory of Open Access Journals (Sweden)

    Shatavisa Mukherjee

    2015-01-01

    Full Text Available Aim: Despite having better tolerability and a wide range of clinical applications over other antidepressants, selective serotonin reuptake inhibitors (SSRIs are also known to be associated with serious adverse effects like suicidal ideation on chronic use. The present study had explored the impact of the chronic use of sertraline, an SSRI, on the behavioral changes in Wistar albino rats. Materials and Methods: The study was conducted on 30 Wistar albino rats of either sex; divided into five groups. Four groups were subjected to chronic mild stress induced by using various stressors randomly scheduled in a week and continued for a period of 3 weeks. The stressed rodents were subjected to sertraline treatment for 9 weeks in different human therapeutic doses extrapolated to animal doses. Behavioral changes were monitored, assessed, and evaluated throughout the treatment phase with the help of tests such as locomotor activity test, forced swim test, tail suspension test, antianxiety test, and sucrose preference test (SPT. Results: All tests except SPT, demonstrated significant (P < 0.05 reduction in depressive-like activity in the stressed rodents by the mid-treatment phase, followed by an abrupt onset of the depressive state by the end of the treatment phase. SPT showed a significant (P < 0.05 increase in sucrose consumption throughout the treatment phase. Conclusion: Behavioral changes following chronic sertraline administration conferred gradual remission of depression state on initial treatment phase, followed by a reversal of effect on chronic use.

  5. Cyclic Vomiting Syndrome

    Science.gov (United States)

    ... or the flu eating certain foods, such as chocolate or cheese, or additives such as caffeine, nitrites— ... people with cyclic vomiting syndrome. Eating, Diet, and Nutrition During the prodrome and vomiting phases of cyclic ...

  6. Superextensions of cyclic semigroups

    Directory of Open Access Journals (Sweden)

    V. M. Gavrylkiv

    2013-06-01

    Full Text Available Given a cyclic semigroup $S$ we study right and left zeros,singleton left ideals, the minimal ideal, left cancelable andright cancelable elements of superextensions $lambda(S$ andcharacterize cyclic semigroups whose superextensions arecommutative.

  7. Cyclic Railway Timetable Optimization

    NARCIS (Netherlands)

    L.W.P. Peeters (Leon)

    2003-01-01

    textabstractCyclic Railway Timetable Optimization describes mathematical models and solution methods for constructing high quality cyclic railway timetables. In a cyclic timetable, a train for a certain destination leaves a certain station at the same time every cycle time, say every half an hour,

  8. Establishment of model of visceral pain due to colorectal distension and its behavioral assessment in rats

    Institute of Scientific and Technical Information of China (English)

    Jian-Ping Yang; Ming Yao; Xing-Hong Jiang; Li-Na Wang

    2006-01-01

    AIM: To establish a visceral pain model via colorectal distension (CRD) and to evaluate the efficiency of behavioral responses of CRD by measuring the score of abdominal withdrawal reflex (AWR) in rats.METHODS: Thirty-eight male SD rats weighing 180-240g were used to establish the visceral pain model. The rat was inserted intra-anally with a 7 cm long flexible latex balloon under ether anesthesia, and colorectal distensions by inflating the balloon with air were made 30 min after recovering from the anesthesia.Five AWR scores (AWR0 to AWR4) were used to assess the intensity of noxious visceral stimuli. It was regarded as the threshold of the minimal pressure (kPa). For abdominal flatting was induced by colorectal distension.RESULTS: A vigorous AWR to distension of the descending colon and rectum was found in 100% of the awake rats tested. The higher the pressure of distension; the higher the score of AWR. The distension pressures of 0, 2.00, 3.33, 5.33 and 8.00 kPa produced different AWR scores (P<0.05). The pain threshold of AWR was constant for up to 80 min after the initial windup (first 1-3 distensions), the mean threshold was 3.69±0.35 kPa. Systemic administration of morphine sulfate elevated the threshold of visceral pain in a dosedependent and naloxone reversible manner.CONCLUSION: Scoring the AWR during colorectal distensions can assess the intensity of noxious visceral stimulus. Flatting of abdomen (AWR 3) to CRD as the visceral pain threshold is clear, constant and reliable.This pain model and its behavioral assessment are good for research on visceral pain and analgesics.

  9. CHF Phenomena by Photographic Study of Boiling Behavior due to Transient Heat Inputs

    OpenAIRE

    Jongdoc Park; Katsuya Fukuda; Qiusheng Liu

    2012-01-01

    The transient boiling heat transfer characteristics in a pool of water and highly wetting liquids such as ethanol and FC-72 due to an exponentially increasing heat input of various rates were investigated using the 1.0 mm diameter experimental heater shaped in a horizontal cylinder for wide ranges of pressure and subcooling. The trend of critical heat flux (CHF) values in relation to the periods was divided into three groups. The CHF belonging to the 1st group with a longer period occurs with...

  10. Mortar constituent of concrete under cyclic compression

    Science.gov (United States)

    Maher, A.; Darwin, D.

    1980-10-01

    The behavior of the mortar constituent of concrete under cyclic compression was studied and a simple analytic model was developed to represent its cyclic behavior. Experimental work consisted of monotonic and cyclic compressive loading of mortar. Two mixes were used, with proportions corresponding to concretes having water cement ratios of 0.5 and 0.6. Forty-four groups of specimens were tested at ages ranging from 5 to 70 days. complete monotonic and cyclic stress strain envelopes were obtained. A number of loading regimes were investigated, including cycles to a constant maximum strain. Major emphasis was placed on tests using relatively high stress cycles. Degradation was shown to be a continuous process and a function of both total strain and load history. No stability or fatigue limit was apparent.

  11. Feasibility of Using PZT Actuators to Study the Dynamic Behavior of a Rotating Disk due to Rotor-Stator Interaction

    Directory of Open Access Journals (Sweden)

    Alexandre Presas

    2014-07-01

    Full Text Available In this paper, PZT actuators are used to study the dynamic behavior of a rotating disk structure due to rotor-stator interaction excitation. The disk is studied with two different surrounding fluids—air and water. The study has been performed analytically and validated experimentally. For the theoretical analysis, the natural frequencies and the associated mode shapes of the rotating disk in air and water are obtained with the Kirchhoff-Love thin plate theory coupled with the interaction with the surrounding fluid. A model for the Rotor Stator Interaction that occurs in many rotating disk-like parts of turbomachinery such as compressors, hydraulic runners or alternators is presented. The dynamic behavior of the rotating disk due to this excitation is deduced. For the experimental analysis a test rig has been developed. It consists of a stainless steel disk (r = 198 mm and h = 8 mm connected to a variable speed motor. Excitation and response are measured from the rotating system. For the rotating excitation four piezoelectric patches have been used. Calibrating the piezoelectric patches in amplitude and phase, different rotating excitation patterns are applied on the rotating disk in air and in water. Results show the feasibility of using PZT to control the response of the disk due to a rotor-stator interaction.

  12. Feasibility of using PZT actuators to study the dynamic behavior of a rotating disk due to rotor-stator interaction.

    Science.gov (United States)

    Presas, Alexandre; Egusquiza, Eduard; Valero, Carme; Valentin, David; Seidel, Ulrich

    2014-07-07

    In this paper, PZT actuators are used to study the dynamic behavior of a rotating disk structure due to rotor-stator interaction excitation. The disk is studied with two different surrounding fluids-air and water. The study has been performed analytically and validated experimentally. For the theoretical analysis, the natural frequencies and the associated mode shapes of the rotating disk in air and water are obtained with the Kirchhoff-Love thin plate theory coupled with the interaction with the surrounding fluid. A model for the Rotor Stator Interaction that occurs in many rotating disk-like parts of turbomachinery such as compressors, hydraulic runners or alternators is presented. The dynamic behavior of the rotating disk due to this excitation is deduced. For the experimental analysis a test rig has been developed. It consists of a stainless steel disk (r = 198 mm and h = 8 mm) connected to a variable speed motor. Excitation and response are measured from the rotating system. For the rotating excitation four piezoelectric patches have been used. Calibrating the piezoelectric patches in amplitude and phase, different rotating excitation patterns are applied on the rotating disk in air and in water. Results show the feasibility of using PZT to control the response of the disk due to a rotor-stator interaction.

  13. Cyclic phosphonium ionic liquids

    Directory of Open Access Journals (Sweden)

    Sharon I. Lall-Ramnarine

    2014-01-01

    Full Text Available Ionic liquids (ILs incorporating cyclic phosphonium cations are a novel category of materials. We report here on the synthesis and characterization of four new cyclic phosphonium bis(trifluoromethylsulfonylamide ILs with aliphatic and aromatic pendant groups. In addition to the syntheses of these novel materials, we report on a comparison of their properties with their ammonium congeners. These exemplars are slightly less conductive and have slightly smaller self-diffusion coefficients than their cyclic ammonium congeners.

  14. Variability of modal behavior in terms of critical speeds of a gear pair due to manufacturing errors and shaft misalignments

    Science.gov (United States)

    Driot, N.; Perret-Liaudet, J.

    2006-05-01

    This paper deals with the variability of the dynamic behavior induced by transmission error of a mass production gear pair. The origins of this variability are due to the manufacturing errors. The tolerances that are associated with shaft misalignment errors, gear tooth profile and lead errors, are considered as geometric independent random parameters. A procedure based on Taguchi's method is used to treat the tolerances statistically. The efficiency of this methodology is demonstrated by considering a simple dynamic model of a single spur gear pair. The predicted variations in dynamic behavior due to tolerances are verified by comparison with results obtained using Monte Carlo simulations. The analyzed parameters are firstly the static transmission error and the time-average mesh stiffness. As a consequence of the variability of the mesh stiffness, statistical variations of natural frequencies are observed for critical modes (high-energy modes). The related critical speed ranges are given too. At last, the variations of the high-energy mode shapes are also observed.

  15. The Effect of Cognitive Behavior Therapy in Insomnia due to Methadone Maintenance Therapy: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Robabeh Soleimani

    2015-09-01

    Full Text Available Background: Sleep disturbance is a common complaint of patients undergoing methadone maintenance therapy (MMT. There are limited studies about the effect of different treatments on insomnia due to MMT. In this study, we evaluated the effect of cognitive-behavioral treatment for insomnia (CBTI on sleep disorders in patients undergoing MMT. Methods: Twenty-two patients with insomnia due to MMT (aged 18-60 years participated in this randomized double-blind clinical trial. The intervention group received CBTI from a clinical psychologist for 8 weeks, whereas the control group received behavioral placebo therapy (BPT. The duration of individual sessions was 45 minutes, which was conducted once a week. The primary outcome was sleep disturbance assessed with Pittsburgh Sleep Quality Index (PSQI. Data were analyzed using SPSS software version 19. Results: Eleven patients were assigned to each group. Two groups were matched according to demographic characteristics (age, marital status, education, and daily methadone doses. Although PSQI score was significantly reduced during weeks 5 and 8 after both interventions, there was a significant difference in intervention versus time interaction (P<0.02. The effects of CBTI versus placebo were significantly different (P<0.001. The time course was also significant (P<0.001. Conclusion: This study showed that CBTI is more effective than BPT in overall sleep quality. We recommend further studies, with a larger sample, on CBTI in patients undergoing MMT.

  16. COMPORTAMIENTO DE UN MATERIAL GRANULAR NO TRATADO EN ENSAYOS TRIAXIALES CÍCLICOS CON PRESIÓN DE CONFINAMIENTO CONSTANTE Y VARIABLE BEHAVIOR OF AN UNBOUND GRANULAR MATERIAL IN CYCLIC TRIAXIAL TESTS WITH CONSTANT AND VARIABLE CONFINING PRESSURE

    Directory of Open Access Journals (Sweden)

    Hugo Alexander Rondón Quintana

    2008-12-01

    Full Text Available En un pavimento, cada una de las capas de la estructura experimenta bajo una carga vehicular ciclos de esfuerzo con componentes vertical, horizontal y de corte. Para el estudio de materiales granulares no tratados (utilizados para conformar capas de base y subbase, la mayor parte de las investigaciones se realizan empleando equipos triaxiales cíclicos en donde sólo la carga vertical es cíclica y la presión de confinamiento permanece constante durante el ensayo. Un ensayo que reproduce mejor la forma como se distribuyen los esfuerzos en estas capas es el ensayo triaxial cíclico con presión de confinamiento variable. En este ensayo se pueden modelar las componentes cíclicas tanto en el sentido vertical como horizontal. A pesar que son ensayos distintos, la ingeniería de pavimentos supone que la respuesta que experimentan estos materiales en estos ensayos es similar, lo anterior basado en algunos estudios realizados en la década de los setenta. En la presente investigación se diseña y desarrolla un programa experimental más detallado, para comparar el comportamiento que desarrolla un material granular no tratado en estos ensayos. De los resultados se evidencia que sólo para algunas trayectorias de esfuerzo, la dirección y la acumulación de la deformación vertical y volumétrica es similar.In a pavement structure, passing wheel loads impose cyclic stresses consisting of vertical, horizontal and shear components. Studies of the behavior of unbound granular materials (UGM, used for base and sub-base layers under cyclic loading are mostly performed using the axisymmetric triaxial test with constant confining pressure (CCP test and a cyclic variation of the axial stress. However, in this type of test only the vertical component of the cyclic stress path is considered. The oscillation of the horizontal stress can be reproduced by an additional cyclic variation of the confining pressure (VCP test. CCP and VCP tests are sometimes assumed to

  17. Affordable Cyclic Voltammetry

    Science.gov (United States)

    Stewart, Greg; Kuntzleman, Thomas S.; Amend, John R.; Collins, Michael J.

    2009-01-01

    Cyclic voltammetry is an important component of the undergraduate chemical curriculum. Unfortunately, undergraduate students rarely have the opportunity to conduct experiments in cyclic voltammetry owing to the high cost of potentiostats, which are required to control these experiments. By using MicroLab data acquisition interfaces in conjunction…

  18. Affordable Cyclic Voltammetry

    Science.gov (United States)

    Stewart, Greg; Kuntzleman, Thomas S.; Amend, John R.; Collins, Michael J.

    2009-01-01

    Cyclic voltammetry is an important component of the undergraduate chemical curriculum. Unfortunately, undergraduate students rarely have the opportunity to conduct experiments in cyclic voltammetry owing to the high cost of potentiostats, which are required to control these experiments. By using MicroLab data acquisition interfaces in conjunction…

  19. Cyclic anamorphic cosmology

    CERN Document Server

    Ijjas, Anna

    2016-01-01

    Cyclic models of the universe have the advantage of avoiding initial conditions problems related to postulating any sort of beginning in time. To date, the only known viable examples of cyclic models have been ekpyrotic. In this paper, we show that the recently proposed anamorphic scenario can also be made cyclic. The key to the cyclic completion is a classically stable, non-singular bounce. Remarkably, even though the bounce construction was originally developed to connect a period of contraction with a period of expansion both described by Einstein gravity, we show here that it can naturally be modified to connect an ordinary contracting phase described by Einstein gravity with a phase of anamorphic smoothing. The paper will present the basic principles and steps in constructing cyclic anamorphic models.

  20. Static and cyclic pullout behavior of cast-in-place headed and bonded anchors with large embedment depths in cracked concrete

    Energy Technology Data Exchange (ETDEWEB)

    Delhomme, F., E-mail: fabien.delhomme@insa-lyon.fr [University of Lyon, INSA-Lyon, LGCIE, F-69621 Villeurbanne (France); Roure, T.; Arrieta, B. [EDF SEPTEN Compagny, Civil Engineering, Villeurbanne (France); Limam, A. [University of Lyon, INSA-Lyon, LGCIE, F-69621 Villeurbanne (France)

    2015-06-15

    Highlights: • Optimizing the design and identifying margin of the headed fasteners used in French nuclear power plants. • Static and cyclic pullout tests on cast in place anchorage composed of an anchor plate welded to four headed or bonded rods. • Experimental data base on tests on anchor plates. • Anchor with large embedment depths in cracked concrete. • Edge effects. - Abstract: The equipment of French nuclear power plants is fixed on reinforced concrete structures with base plate with headed fasteners. EDF decided to carry out an experimental research program in partnership with LGCIE in order to optimize the design of the headed fasteners and identify margin. This article introduces the results of pullout tests on anchors with large embedment cast in place in a reinforced concrete block. The anchorage are composed of an anchor plate welded to four ribbed bars or headed smooth studs. The studied parameters are: the type of loading (static or cyclic), the edge distance, the state of cracking of the concrete block. The anchors with headed rods or ribbed bars have a steel rod failure mode in agreement with their initial design. However, an optimization of the size on the headed anchors seems to be expected in order to improve their installation. This experimental campaign will provide a data base enabling the development of numerical models in order to improve the design.

  1. Development of a design methodology for high temperature cyclic applications of materials which experience cyclic softening

    Energy Technology Data Exchange (ETDEWEB)

    Marriott, D.L.; Stubbins, J.F. (Illinois Univ., Urbana, IL (USA). Dept. of Mechanical and Industrial Engineering)

    1988-12-01

    The project has as its original focus the high temperature behavior of 2.25 Cr-1 Mo steel, heat treated to produce a predominantly bainitic microstructure and the load carrying response of components made of this material. Experiments were carried out on uniform and notched specimens under both steady and cyclic loading using specially acquired electromechanical test machines. It emerged that a very important feature of mechanical behavior under the conditions of interest was the strong tendency of this material to cyclically soften, particularly at high temperature in the creep range, giving the illusion of a severe creep-fatigue interaction under certain conditions. This finding led to a significant component of the project being devoted to investigation of the effects of local, as opposed to generalized, cyclic softening, and the implications this phenomenon might have on the setting of allowable design stress limits. The format of this report is as follows: The second chapter is a review of the work carried out in approximately chronological order under the headings of work was carried out under the following: (1) 2.25 Cr 1 Mo Steel -- Elevated Temperature Fatigue and Environmental Effects; (2) Preliminary Studies of Advanced Austenitics; (3) A Uniaxial Constitutive Model for Cyclic Softening; (4) The Iso-Cyclic Stress-Strain Approach to Evaluation of Components in Cyclic Softening Materials; (5) Testing of High Temperature Austenitic Alloys; and (6) Design Methodology for Aging Materials -- Application to Cyclic Softening. 65 refs., 39 figs., 7 tabs.

  2. Corrosion Behavior of N80 Steel under Immersion and Wet-dry Cyclic Condition%N80钢模拟全浸区和干湿交替试样的腐蚀行为

    Institute of Scientific and Technical Information of China (English)

    刘建国; 李言涛; 侯保荣

    2012-01-01

    利用SEM和XRD对锈层的腐蚀形貌和腐蚀产物组成进行观察和分析,研究了N80裸钢和模拟全浸区腐蚀试样及模拟干湿交替腐蚀试样在两种海水介质中的极化行为。结果表明,干湿交替腐蚀阴极过程溶解氧还原的极限扩散控制特征基本消失,而受腐蚀产物还原为主的电荷传递控制。N80钢干湿交替腐蚀电流不仅包括钢自身的腐蚀电流,还包括腐蚀产物的氧化还原电流,导致了N80钢模拟干湿交替的腐蚀速率远大于全浸区腐蚀速率。%The polarization behavior of N80 steel was obtained from the corroded steel samples under wet-dry cyclic condition and compared with that from bare steel and immersion samples. The corrosion morphology and corrosion products of the steel samples were characterized using scanning electron microscopy (SEM) and X-ray diffraction (XRD). The cathodic reduction of samples under wet-dry cyclic condition was controlled mainly by the charge transfer step of reduction of corrosion products rather than the limiting diffusion control of dissolved oxygen. The matrix metal of the samples was corroded and the rust itself also took part in the reduction processes and hence increased the corrosion rate of the steel samples under wet-dry cyclic condition.

  3. Fully undrained cyclic loading simulation on unsaturated soils using an elastoplastic model for unsaturated soils

    Directory of Open Access Journals (Sweden)

    Komolvilas Veerayut

    2016-01-01

    Full Text Available Several researchers have reported that Bishop’s mean effective stress decreases in unsaturated soils under fully undrained cyclic loading conditions, and unsaturated soils are finally liquefied in a similar manner as saturated soils. This paper presents a series of simulations of such fully undrained cyclic loading on unsaturated soils using an elastoplastic model of the unsaturated soil. This model is formulated using the Bishop’s effective stress tensor incorporating the following concepts: the volumetric movement of the state boundary surface containing the normal consolidation line and the critical state line due to the variation in the degree of saturation, a soil water characteristic curve model considering the effect of specific volume and hysteresis, the subloading surface model, and Boyle’s law. Comparisons between the simulation results and the experimental ones show that the model agreed well with the unsaturated soil behavior under cyclic loading. Finally, the typical cyclic behavior of unsaturated soils under fully undrained conditions, such as the mechanism of liquefaction of unsaturated soils, the compression behavior, and an increase in the degree of saturation, are described through the proposed simulation results.

  4. Real Topological Cyclic Homology

    DEFF Research Database (Denmark)

    Høgenhaven, Amalie

    The main topics of this thesis are real topological Hochschild homology and real topological cyclic homology. If a ring or a ring spectrum is equipped with an anti-involution, then it induces additional structure on the topological Hochschild homology spectrum. The group O(2) acts on the spectrum......, where O(2) is the semi-direct product of T, the multiplicative group of complex number of modulus 1, by the group G=Gal(C/R). We refer to this O(2)-spectrum as the real topological Hochschild homology. This generalization leads to a G-equivariant version of topological cyclic homology, which we call...... real topological cyclic homology. The first part of the thesis computes the G-equivariant homotopy type of the real topological cyclic homology of spherical group rings at a prime p with anti-involution induced by taking inverses in the group. The second part of the thesis investigates the derived G...

  5. Cyclical Behavior Study of Capital Buffer Based on the Evidence of City Commercial Bank%基于城市商业银行的资本缓冲周期性行为研究

    Institute of Scientific and Technical Information of China (English)

    吴成颂; 郭开春; 徐慧; 黄送钦

    2016-01-01

    Using an unbalanced panel data of 50 China’s city commercial bank from 2005 to 2014 in single-step system GMM estimation method, this paper studied the relationship between the e-conomic cycle and the capital buffer, and analyzed the effects of the pressure of prudential super-vision and equity heterogeneity to cyclical capital buffer behavior. Results show that there is a negative correlation between the economic cycle and capital buffers:the capital buffer has signifi-cant pro-cyclicality. Yet banks which under prudential supervision pressure, it’s Pro-cyclical fea-tures of capital buffer is weakened compared with other banks. Moreover, the nature of share-holding and foreign strategic investors of Ownership Characteristics can impact the pro-cyclicality of capital buffer, but the effect is not significant. Therefore, the City bank should to strengthen the banking system, establish a "capital buffer pool" and implement prudential regulatory policy in order to maintain its stability.%运用我国50家城市商业银行2005-2014年度的非平衡面板数据进行单步系统GMM估计,论文研究了资本缓冲与经济周期之间的关系,并分析了审慎监管压力和股权异质性结构特征对资本缓冲周期性行为的影响。实证分析结果表明城商行资本缓冲与经济周期之间呈现负相关,即资本缓冲具有显著的顺周期性。而处于审慎监管压力下的城商行,其资本缓冲的顺周期性特征较其他城商行有所减弱。此外,股权特征中控股性质和有无境外投资者持股可以影响城商行资本缓冲的顺周期性行为,但效果并不显著。因此,对于城商行而言,要加强银行体系的建设,建立“缓冲资本池”,并执行监管部门的审慎政策,以保持自身的稳定。

  6. Behavior of concrete-filled rectangular steel tubular columns under cyclical loading%方钢管混凝土柱滞回性能研究

    Institute of Scientific and Technical Information of China (English)

    李前; 卫建军

    2012-01-01

    以含钢率、长细比、材料强度等为主要参数,在确定钢材和核心混凝土在循环荷载作用下的应力-应变关系模型的基础上,利用有限元软件ANSYS,对方钢管混凝土柱在循环荷载作用下全过程进行了计算,以模拟地震作用下方钢管混凝土柱的实际受力性能.研究表明:方钢管混凝土柱荷载-位移滞回曲线呈比较饱满的“梭形”,没有明显的捏缩现象,达到极限荷载后,仍表现出良好的延性和后期变形能力,能够满足实际工程中大跨度、重荷载的要求,是一种良好的结构形式.%Considering the steel ratio, slenderness ratio, and the material strength as the main variable parameters, based on the determination of the stress-strain relation of the steel and core concrete under the cyclic loading, use the finite element software ANSYS to calculate the concrete-filled rectangular steel tubular columns under cyclic loading in the whole process, which simulates the mechanical properties of concrete-filled rectangular steel tubular columns in actual earthquake. Research shows that: the load versus displacement hysteretic curves of concrete-filled rectangular steel tubular columns was relatively full "spindle" .without obvious pinch phenomenon. After the limit load, model structure still showed good ductility and post-deformation. The concrete-filled rectangular steel tubular columns can meet the requirements of the real projects with large span and heavy load.

  7. Cup products in Hopf cyclic cohomology via cyclic modules I

    CERN Document Server

    Rangipour, Bahram

    2007-01-01

    This is the first one in a series of two papers on the continuation of our study in cup products in Hopf cyclic cohomology. In this note we construct cyclic cocycles of algebras out of Hopf cyclic cocycles of algebras and coalgebras. In the next paper we consider producing Hopf cyclic cocycle from "equivariant" Hopf cyclic cocycles. Our approach in both situations is based on (co)cyclic modules and bi(co)cyclic modules together with Eilenberg-Zilber theorem which is different from the old definition of cup products defined via traces and cotraces on DG algebras and coalgebras.

  8. Cyclic polymers from alkynes

    Science.gov (United States)

    Roland, Christopher D.; Li, Hong; Abboud, Khalil A.; Wagener, Kenneth B.; Veige, Adam S.

    2016-08-01

    Cyclic polymers have dramatically different physical properties compared with those of their equivalent linear counterparts. However, the exploration of cyclic polymers is limited because of the inherent challenges associated with their synthesis. Conjugated linear polyacetylenes are important materials for electrical conductivity, paramagnetic susceptibility, optical nonlinearity, photoconductivity, gas permeability, liquid crystallinity and chain helicity. However, their cyclic analogues are unknown, and therefore the ability to examine how a cyclic topology influences their properties is currently not possible. We have solved this challenge and now report a tungsten catalyst supported by a tetraanionic pincer ligand that can rapidly polymerize alkynes to form conjugated macrocycles in high yield. The catalyst works by tethering the ends of the polymer to the metal centre to overcome the inherent entropic penalty of cyclization. Gel-permeation chromatography, dynamic and static light scattering, viscometry and chemical tests are all consistent with theoretical predictions and provide unambiguous confirmation of a cyclic topology. Access to a wide variety of new cyclic polymers is now possible by simply choosing the appropriate alkyne monomer.

  9. Early onset behavioral variant frontotemporal dementia due to the C9ORF72 hexanucleotide repeat expansion: psychiatric clinical presentations.

    Science.gov (United States)

    Arighi, Andrea; Fumagalli, Giorgio G; Jacini, Francesca; Fenoglio, Chiara; Ghezzi, Laura; Pietroboni, Anna M; De Riz, Milena; Serpente, Maria; Ridolfi, Elisa; Bonsi, Rossana; Bresolin, Nereo; Scarpini, Elio; Galimberti, Daniela

    2012-01-01

    A hexanucleotide repeat expansion in the first intron of C9ORF72 has been shown to be responsible for a high number of familial cases of amyotrophic lateral sclerosis or frontotemporal lobar degeneration with or without concomitant motor neuron disease phenotype and TDP-43 based pathology. Here, we report on three cases carrying the hexanucleotide repeat expansion with an atypical presentation consisting in the development of psychiatric symptoms. Patient #1, a 53 year old man with positive family history for dementia, presented with mood deflection, characterized by apathy, social withdraw, and irritability in the last two years. He was diagnosed with "mild cognitive impairment due to depressive syndrome" six months later and subsequently with Alzheimer's disease. Patient #2, a woman with positive family history for dementia, developed behavioral disturbances, aggressiveness, and swearing at 57 years of age. Patient #3 presented, in the absence of brain atrophy, with mystical delirium with auditory hallucinations at 44 years of age, and did not present neurological symptoms over a 7-year follow up. The description of these cases underlines that the hexanucleotide repeat expansion in chromosome 9 could be associated with early onset psychiatric presentations.

  10. The cyclical component factor model

    DEFF Research Database (Denmark)

    Dahl, Christian Møller; Hansen, Henrik; Smidt, John

    Forecasting using factor models based on large data sets have received ample attention due to the models' ability to increase forecast accuracy with respect to a range of key macroeconomic variables in the US and the UK. However, forecasts based on such factor models do not uniformly outperform...... the simple autoregressive model when using data from other countries. In this paper we propose to estimate the factors based on the pure cyclical components of the series entering the large data set. Monte Carlo evidence and an empirical illustration using Danish data shows that this procedure can indeed...

  11. In aging, the vulnerability of rat brain mitochondria is enhanced due to reduced level of 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNP) and subsequently increased permeability transition in brain mitochondria in old animals.

    Science.gov (United States)

    Krestinina, Olga; Azarashvili, Tamara; Baburina, Yulia; Galvita, Anastasia; Grachev, Dmitry; Stricker, Rolf; Reiser, Georg

    2015-01-01

    Aging is accompanied by progressive dysfunction of mitochondria associated with a continuous decrease of their capacity to produce ATP. Mitochondria isolated from brain of aged animals show an increased mitochondrial permeability transition pore (mPTP) opening. We recently detected new regulators of mPTP function in brain mitochondria, the enzyme 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and its substrates 2', 3'-cAMP and 2', 3'-cNADP, and the neuronal protein p42(IP4). Here, we compared parameters of mPTP opening in non-synaptic brain mitochondria isolated from young and old rats. In mitochondria from old rats (>18 months), mPTP opening occurred at a lower threshold of Ca(2+) concentration than in mitochondria from young rats (aging was accompanied by decreased levels of voltage-dependent anion channel (VDAC; by 69%) and of p42(IP4) (by 59%). Thus, reduced levels of CNP in mitochondria could lead to a rise in the concentration of the mPTP promoter 2', 3'-cAMP. The level of CNP and p42(IP4) and, probably VDAC, might be essential for myelination and electrical activity of axons. We propose that in aging the reduction in the level of these proteins leads to mitochondrial dysfunction, in particular, to a decreased threshold Ca(2+) concentration to induce mPTP opening. This might represent initial steps of age-related mitochondrial dysfunction, resulting in myelin and axonal pathology.

  12. Infertility in Female Mice with a Gain-of-Function Mutation in the Luteinizing Hormone Receptor Is Due to Irregular Estrous Cyclicity, Anovulation, Hormonal Alterations, and Polycystic Ovaries1

    Science.gov (United States)

    Hai, Lan; McGee, Stacey R.; Rabideau, Amanda C.; Paquet, Marilène; Narayan, Prema

    2015-01-01

    The luteinizing hormone receptor, LHCGR, is essential for fertility in males and females, and genetic mutations in the receptor have been identified that result in developmental and reproductive defects. We have previously generated and characterized a mouse model (KiLHRD582G) for familial male-limited precocious puberty caused by an activating mutation in the receptor. We demonstrated that the phenotype of the KiLHRD582G male mice is an accurate phenocopy of male patients with activating LHCGR mutations. In this study, we observed that unlike women with activating LHCGR mutations who are normal, female KiLHRD582G mice are infertile. Mice exhibit irregular estrous cyclicity, anovulation, and precocious puberty. A temporal study from 2–24 wk of age indicated elevated levels of progesterone, androstenedione, testosterone, and estradiol and upregulation of several steroidogenic enzyme genes. Ovaries of KiLHRD582G mice exhibited significant pathology with the development of large hemorrhagic cysts as early as 3 wk of age, extensive stromal cell hyperplasia and hypertrophy with luteinization, numerous atretic follicles, and granulosa cell tumors. Ovulation could not be rescued by the addition of exogenous gonadotropins. The body weights of the KiLHRD582G mice were higher than wild-type counterparts, but there was no increase in the body fat composition or metabolic abnormalities such as impaired glucose tolerance and insulin resistance. These studies demonstrate that activating LHCGR mutations do not produce the same phenotype in female mice as in humans and clearly illustrate species differences in the expression and regulation of LHCGR in the ovary, but not in the testis. PMID:26040673

  13. Phase-space dependent critical gradient behavior of fast-ion transport due to Alfvén eigenmodes

    Science.gov (United States)

    Collins, C. S.; Heidbrink, W. W.; Podestà, M.; White, R. B.; Kramer, G. J.; Pace, D. C.; Petty, C. C.; Stagner, L.; Van Zeeland, M. A.; Zhu, Y. B.; The DIII-D Team

    2017-08-01

    Experiments in the DIII-D tokamak show that many overlapping small-amplitude Alfvén eigenmodes (AEs) cause fast-ion transport to sharply increase above a critical threshold in beam power, leading to fast-ion density profile resilience and reduced fusion performance. The threshold is above the AE linear stability limit and varies between diagnostics that are sensitive to different parts of fast-ion phase-space. Comparison with theoretical analysis using the nova and orbit codes shows that, for the neutral particle diagnostic, the threshold corresponds to the onset of stochastic particle orbits due to wave-particle resonances with AEs in the measured region of phase space. The bulk fast-ion distribution and instability behavior was manipulated through variations in beam deposition geometry, and no significant differences in the onset threshold outside of measurement uncertainties were found, in agreement with the theoretical stochastic threshold analysis. Simulations using the ‘kick model’ produce beam ion density gradients consistent with the empirically measured radial critical gradient and highlight the importance of including the energy and pitch dependence of the fast-ion distribution function in critical gradient models. The addition of electron cyclotron heating changes the types of AEs present in the experiment, comparatively increasing the measured fast-ion density and radial gradient. These studies provide the basis for understanding how to avoid AE transport that can undesirably redistribute current and cause fast-ion losses, and the measurements are being used to validate AE-induced transport models that use the critical gradient paradigm, giving greater confidence when applied to ITER.

  14. Outbreak of a cluster with epidemic behavior due to Serratia marcescens after colistin administration in a hospital setting.

    Science.gov (United States)

    Merkier, Andrea Karina; Rodríguez, María Cecilia; Togneri, Ana; Brengi, Silvina; Osuna, Carolina; Pichel, Mariana; Cassini, Marcelo H; Centrón, Daniela

    2013-07-01

    Serratia marcescens causes health care-associated infections with important morbidity and mortality. Particularly, outbreaks produced by multidrug-resistant isolates of this species, which is already naturally resistant to several antibiotics, including colistin, are usually described with high rates of fatal outcomes throughout the world. Thus, it is important to survey factors associated with increasing frequency and/or emergence of multidrug-resistant S. marcescens nosocomial infections. We report the investigation and control of an outbreak with 40% mortality due to multidrug-resistant S. marcescens infections that happened from November 2007 to April 2008 after treatment with colistin for Acinetobacter baumannii meningitis was started at hospital H1 in 2005. Since that year, the epidemiological pattern of frequently recovered species has changed, with an increase of S. marcescens and Proteus mirabilis infections in 2006 in concordance with a significant decrease of the numbers of P. aeruginosa and A. baumannii isolates. A single pulsed-field gel electrophoresis (PFGE) cluster of S. marcescens isolates was identified during the outbreak. When this cluster was compared with S. marcescens strains (n = 21) from 10 other hospitals (1997 to 2010), it was also identified in both sporadic and outbreak isolates circulating in 4 hospitals in Argentina. In132::ISCR1::blaCTX-M-2 was associated with the multidrug-resistant cluster with epidemic behavior when isolated from outbreaks. Standard infection control interventions interrupted transmission of this cluster even when treatment with colistin continued in several wards of hospital H1 until now. Optimizing use of colistin should be achieved simultaneously with improved infection control to prevent the emergence of species naturally resistant to colistin, such as S. marcescens and P. mirabilis.

  15. Cyclic and isothermal oxidation behavior of 2.25Cr-1Mo steel; Estudio del comportamiento del acero 2.25Cr-1Mo frente a los fenomenos de oxidacion ciclica e isoterma

    Energy Technology Data Exchange (ETDEWEB)

    Proy, M.; Utrilla, M. v.; Otero, E.

    2014-04-01

    Cyclic and isothermal oxidation of chromium-molybdenum steel 2.25Cr-1Mo were analyzed at 550 degree centigrade and 650 degree centigrade during 360 hours in air atmospheres. The cycles were performed with two stages; one of heating in furnace during 90 minutes and then the sample were cooled to 50 degree centigrade by air flow. Thermogravimetric analyses were performed to obtain high temperature corrosion kinetics. Several characterization techniques have been used to identify the corrosion mechanism, as X-Ray Diffraction (XRD), Optical Microscopy (OM) and Scanning Electron Microscopy (SEM). Thermal cycling tests can changes the corrosion mechanism, due cracks propagation in oxide scale, that witch can favors the access of oxidant agent to the substrate. (Author)

  16. Generalized Wideband Cyclic MUSIC

    Directory of Open Access Journals (Sweden)

    Zhang-Meng Liu

    2009-01-01

    Full Text Available The method of Spectral Correlation-Signal Subspace Fitting (SC-SSF fails to separate wideband cyclostationary signals with coherent second-order cyclic statistics (SOCS. Averaged Cyclic MUSIC (ACM method made up for the drawback to some degree via temporally averaging the cyclic cross-correlation of the array output. This paper interprets ACM from another perspective and proposes a new DOA estimation method by generalizing ACM for wideband cyclostationary signals. The proposed method successfully makes up for the aforementioned drawback of SC-SSF and obtains a more satisfying performance than ACM. It is also demonstrated that ACM is a simplified form of the proposed method when only a single spectral frequency is exploited, and the integration of the frequencies within the signal bandwidth helps the new method to outperform ACM.

  17. The cyclic reduction algorithm

    Science.gov (United States)

    Bini, Dario; Meini, Beatrice

    2009-05-01

    Cyclic reduction is an algorithm invented by G.H. Golub and R. W. Hockney in the mid 1960s for solving linear systems related to the finite differences discretization of the Poisson equation over a rectangle. Among the algorithms of Gene Golub, it is one of the most versatile and powerful ever created. Recently, it has been applied to solve different problems from different applicative areas. In this paper we survey the main features of cyclic reduction, relate it to properties of analytic functions, recall its extension to solving more general finite and infinite linear systems, and different kinds of nonlinear matrix equations, including algebraic Riccati equations, with applications to Markov chains, queueing models and transport theory. Some new results concerning the convergence properties of cyclic reduction and its applicability are proved under very weak assumptions. New formulae for overcoming breakdown are provided.

  18. Cyclical Long-term Unemployment, Skill Loss, and Monetary Policy

    OpenAIRE

    2012-01-01

    Movements in long-term unemployment (LTU) exhibit a substantial cyclical component. I develop a business cycle model featuring labor market frictions and skill loss during unemployment to capture various stylized facts about the cyclical behavior of long-term unemployment. I find that the skill loss mechanism helps reproduce negative duration dependence, high persistence in unemployment and output, volatility patterns across macroeconomic variables and the behavior of the incidence of LTU aro...

  19. Compressive cyclic ratcheting and fatigue of synthetic, soft biomedical polymers in solution.

    Science.gov (United States)

    Miller, Andrew T; Safranski, David L; Smith, Kathryn E; Guldberg, Robert E; Gall, Ken

    2016-02-01

    The use of soft, synthetic materials for the replacement of soft, load-bearing tissues has been largely unsuccessful due to a lack of materials with sufficient fatigue and wear properties, as well as a lack of fundamental understanding on the relationship between material structure and behavior under cyclic loads. In this study, we investigated the response of several soft, biomedical polymers to cyclic compressive stresses under aqueous conditions and utilized dynamic mechanical analysis and differential scanning calorimetry to evaluate the role of thermo-mechanical transitions on such behavior. Studied materials include: polycarbonate urethane, polydimethylsiloxane, four acrylate copolymers with systematically varied thermo-mechanical transitions, as well as bovine meniscal tissue for comparison. Materials showed compressive moduli between 2.3 and 1900MPa, with polycarbonate urethane (27.3MPa) matching closest to meniscal tissue (37.0MPa), and also demonstrated a variety of thermo-mechanical transition behaviors. Cyclic testing resulted in distinct fatigue-life curves, with failure defined as either classic fatigue fracture or a defined increased in maximum strain due to ratcheting. Our study found that polymers with sufficient dissipation mechanisms at the testing temperature, as evidenced by tan delta values, were generally tougher than those with less dissipation and exhibited ratcheting rather than fatigue fracture much like meniscal tissue. Strain recovery tests indicated that, for some toughened polymers, the residual strain following our cyclic loading protocol could be fully recovered. The similarity in ratcheting behavior, and lack of fatigue fracture, between the meniscal tissue and toughened polymers indicates that such polymers may have potential as artificial soft tissue.

  20. Cyclic Plastic Deformation and Welding Simulation

    NARCIS (Netherlands)

    Ten Horn, C.H.L.J.

    2003-01-01

    One of the concerns of a fitness for purpose analysis is the quantification of the relevant material properties. It is known from experiments that the mechanical properties of a material can change due to a monotonic plastic deformation or a cyclic plastic deformation. For a fitness for purpose anal

  1. Cyclic Vomiting Syndrome

    Science.gov (United States)

    ... digestive diseases specialist (gastroenterologist). If you or your child is in the middle of a severe vomiting episode, the doctor may ... system disorders There's no cure for cyclic vomiting syndrome, so treatment ... may be prescribed: Anti-nausea drugs Sedatives Medications ...

  2. On Expanded Cyclic Codes

    CERN Document Server

    Wu, Yingquan

    2008-01-01

    The paper has a threefold purpose. The first purpose is to present an explicit description of expanded cyclic codes defined in $\\GF(q^m)$. The proposed explicit construction of expanded generator matrix and expanded parity check matrix maintains the symbol-wise algebraic structure and thus keeps many important original characteristics. The second purpose of this paper is to identify a class of constant-weight cyclic codes. Specifically, we show that a well-known class of $q$-ary BCH codes excluding the all-zero codeword are constant-weight cyclic codes. Moreover, we show this class of codes achieve the Plotkin bound. The last purpose of the paper is to characterize expanded cyclic codes utilizing the proposed expanded generator matrix and parity check matrix. We analyze the properties of component codewords of a codeword and particularly establish the precise conditions under which a codeword can be represented by a subbasis. With the new insights, we present an improved lower bound on the minimum distance of...

  3. The Cyclicality of Bank Lending Behavior based on the Evidence from Chinese Listed Banks%中国上市银行信贷行为的周期性研究

    Institute of Scientific and Technical Information of China (English)

    刘辛元

    2015-01-01

    This paper studies the credit cyclicality of Chines's listed banks based on the listed banks data from 1998 to 2013 by using fixed effects model. The empirical results show there is phases pro-cyclicality and phases counter-cyclicality of the listed banks' lending supply, and there is significant effect between the size of bank and periodicity. Due to the Chinese government intervenes macroeconomic and bank management frequently. The intervention measures will weaken the policy effects of the bank regulatory authority. This paper suggests Chinese government and bank regulatory authority should coordinate with each other on policies making. The coordination will be benefit to prevent economic and financial crisis, promote China's economic and financial system health and sustainable development.%文章基于中国上市银行1998-2013年的数据,采用固定效应模型,对16家中国上市银行信贷行为的周期性进行了研究。研究表明,中国上市银行的信贷行为表现为阶段顺周期性和阶段逆周期性;银行规模对其周期性也有较大影响,规模较小银行或同一银行在规模较小阶段其信贷的逆周期性更显著。由于当前我国政府对宏观经济及银行行为的干预程度较大,银行监管当局所制定监管政策的针对性及有效性将受到很大削弱,因此文章建议政府的宏观经济调控政策与银行的监管政策必须相互协调,这是未来防范经济危机与金融危机,促进中国经济健康持续发展,保持中国金融系统稳健经营的必然选择。

  4. Cyclic-AMP metabolism in synaptic growth, strength and precision: Neural and behavioral phenotype-specific counterbalancing effects between dnc PDE and rut AC mutations

    OpenAIRE

    Ueda, Atsushi; Wu, Chun-Fang

    2012-01-01

    Two classic learning mutants in Drosophila, rutabaga (rut) and dunce (dnc), are defective in cAMP synthesis and degradation, respectively, exhibiting a variety of neuronal and behavioral defects. We ask how the opposing effects of these mutations on cAMP levels modify subsets of phenotypes, and whether any specific phenotypes could be ameliorated by biochemical counter balancing effects in dnc rut double mutants. Our study at larval neuromuscular junctions (NMJs) demonstrate that dnc mutation...

  5. Mechanical behavior under cyclic loading of the 18R-6R high-hysteresis martensitic transformation in Cu-Zn-Al alloys with nanoprecipitates

    Energy Technology Data Exchange (ETDEWEB)

    Castro Bubani, Franco de, E-mail: franco@cab.cnea.gov.ar [Centro Atómico Bariloche (CNEA), Av. E. Bustillo Km. 9, 5 (8400) S.C.de Bariloche (Argentina); CONICET, Buenos Aires (Argentina); Instituto Balseiro, Universidad Nacional de Cuyo, Bariloche, Rio Negro (Argentina); Sade, Marcos, E-mail: sade@cab.cnea.gov.ar [Centro Atómico Bariloche (CNEA), Av. E. Bustillo Km. 9, 5 (8400) S.C.de Bariloche (Argentina); CONICET, Buenos Aires (Argentina); Instituto Balseiro, Universidad Nacional de Cuyo, Bariloche, Rio Negro (Argentina); Lovey, Francisco, E-mail: lovey@cab.cnea.gov.ar [Centro Atómico Bariloche (CNEA), Av. E. Bustillo Km. 9, 5 (8400) S.C.de Bariloche (Argentina); Instituto Balseiro, Universidad Nacional de Cuyo, Bariloche, Rio Negro (Argentina)

    2013-08-10

    Mechanical damping applications could benefit from the large hysteresis, large pseudoelastic strain and the fact that the transformation stresses of the 18R↔6R martensite–martensite transformation depend very little on temperature in Cu-based alloys. This work presents the 18R↔6R mechanical cycling behavior of CuZnAl shape-memory alloy single crystals with electronic concentration e/a=1.48. A fine distribution of gamma phase nanoprecipitates is introduced to prevent plastic deformation of the 6R phase. Results show that, although significant 6R stabilization is observed at very low frequencies (below 10{sup −2} Hz), it is possible to obtain more than 1000 stable pseudoelastic cycles with only minor changes in transformation stresses and hysteresis width at frequencies above 10{sup −1} Hz. A more pronounced decrease in transformation stresses is observed after 1000 cycles. Nevertheless, the decrease in hysteresis is small up to 2000 cycles. Reported and present results indicate that pair interchange of atoms can explain the stabilization of 6R under quasistatic experimental conditions. However, at higher frequencies of cycling, stabilization of this martensite shows additional features, leading to a dynamic stabilization with slight effects on the mechanical behavior at the required frequency and number of cycles. On the whole, the behavior of this transformation is unique and very promising.

  6. A new type of bounding surface plasticity model for cyclic behavior of saturated clay%适用于饱和黏土循环动力分析的新型边界面塑性模型

    Institute of Scientific and Technical Information of China (English)

    胡存; 刘海笑

    2011-01-01

    In order to precisely evaluate the response of embedded offshore structures in a complicated ocean environment, it is essential to develop more simple and more accurate soil models under cyclic loading. Based on the generalized isotropic hardening rule, a new type of bounding surface plasticity model is herein proposed which is capable of modeling the undrained saturated clay behavior under cyclic loading. According to the movement of the hardening center, the new bounding surface plasticity model for predicting the evolvement of clay anisotropy can not only be adapted to the hardening isotropically but also kinematically. Meanwhile, virgin loading, unloading and reloading processes are treated differently when calculating the hardening modulus to predict the accumulation of permanent strain and pore pressure. The hardening center is taken as the mapping origin in the radial mapping rule to simulate the hysteresis property of clay under cyclic loading. The results of model simulations show an encouraging agreement with the experi- mental data from triaxial tests subjected to both short-term high stress level and long-term low stress level cyclic loading conditions.%为了合理评估嵌入式海洋工程结构在海洋环境中的动力响应和工作性能,有必要建立一种形式简单且能真实模拟饱和土体复杂动力特性的本构模型。本文基于广义各向同性硬化准则提出了适用于描述循环荷载作用下饱和黏土复杂动力特性的新型边界面塑性模型。模型引入广义各向同性硬化中心,实现边界面的等向硬化和运动硬化,以反映循环荷载作用下饱和黏土各向异性的演化。同时,土体的连续循环加载过程被分为三类加载事件:初始加载、卸载和再加载事件,采用不同的插值公式计算其塑性模量,以模拟循环塑性应变和孔压的累积;以该硬化中心作为映射中心,从而体现土体在卸载过程中产生的塑性变形

  7. Cyclic Strain Enhances Cellular Uptake of Nanoparticles

    Directory of Open Access Journals (Sweden)

    Jia Hu

    2015-01-01

    Full Text Available Nanoparticles (NPs have gained increasing interest in recent years due to their potential use as drug carrier, imaging, and diagnostic agents in pharmaceutical and biomedical applications. While many cells in vivo experience mechanical forces, little is known about the correlation of the mechanical stimulation and the internalization of NPs into cells. This paper investigates the effects of applied cyclic strain on NP uptake by cells. Bovine aortic endothelial cells (BAECs were cultured on collagen-coated culture plates and placed under cyclic equal-axial strains. NPs of sizes ranging from 50 to 200 nm were loaded at a concentration of 0.02 mg/mL and cyclic strains from 5 to 15% were applied to the cells for one hour. The cyclic strain results in a significant enhancement in NP uptake, which increases almost linearly with strain level. The enhanced uptake also depends on size of the NPs with the highest uptake observed on 100 nm NP. The effect of enhanced NP uptake lasts around 13 hours after cyclic stretch. Such in vitro cell stretch systems mimic physiological conditions of the endothelial cells in vivo and could potentially serve as a biomimetic platform for drug therapeutic evaluation.

  8. Cyclic Voltammograms from First Principles

    DEFF Research Database (Denmark)

    Karlberg, Gustav; Jaramillo, Thomas; Skulason, Egill

    2007-01-01

    Cyclic voltammetry is a fundamental experimental tool for characterizing electrochemical surfaces. Whereas cyclic voltammetry is widely used within the field of electrochemistry, a way to quantitatively and directly relate the cyclic voltammogram to ab initio calculations has been lacking, even f...

  9. A case of psychosis due to Fahr's syndrome and response to behavioral disturbances with risperidone and oxcarbazepine

    Science.gov (United States)

    Faye, Abhijeet Dhawalram; Gawande, Sushil; Tadke, Rahul; Kirpekar, Vivek C.; Bhave, Sudhir H.

    2014-01-01

    Calcification of basal ganglia or Fahr's syndrome is a rare disease characterized by bilateral and symmetrical intracranial deposition of calcium mainly in cerebral basal ganglia. Motor and neuropsychiatric symptoms are prominent features. We report a case presented with a few motor symptoms, features of delirium and prominent psychiatric symptoms (disorganized behavior) predominantly evident after the improvement in delirium. Radiological findings were suggestive of bilateral basal ganglia calcification. Parathyroid hormone levels were low with no significant findings in other investigations and negative family history. Patient showed significant improvement in behavioral disturbances with risperidone, low dose of lorazepam, oxcarbazepine, and memantine. PMID:24891710

  10. Dynamics of cyclic machines

    CERN Document Server

    Vulfson, Iosif

    2015-01-01

    This book focuses on modern methods of oscillation analysis in machines, including cyclic action mechanisms (linkages, cams, steppers, etc.). It presents schematization techniques and mathematical descriptions of oscillating systems, taking into account the variability of the parameters and nonlinearities, engineering evaluations of dynamic errors, and oscillation suppression methods. The majority of the book is devoted to the development of new methods of dynamic analysis and synthesis for cyclic machines that form regular oscillatory systems with multiple duplicate modules.  There are also sections examining aspects of general engineering interest (nonlinear dissipative forces, systems with non-stationary constraints, impacts and pseudo-impacts in clearances, etc.)  The examples in the book are based on the widely used results of theoretical and experimental studies as well as engineering calculations carried out in relation to machines used in the textile, light, polygraphic and other industries. Particu...

  11. The Cyclic Model Simplified

    CERN Document Server

    Steinhardt, P J; Steinhardt, Paul J.; Turok, Neil

    2004-01-01

    The Cyclic Model attempts to resolve the homogeneity, isotropy, and flatness problems and generate a nearly scale-invariant spectrum of fluctuations during a period of slow contraction that precedes a bounce to an expanding phase. Here we describe at a conceptual level the recent developments that have greatly simplified our understanding of the contraction phase and the Cyclic Model overall. The answers to many past questions and criticisms are now understood. In particular, we show that the contraction phase has equation of state w>1 and that contraction with w>1 has a surprisingly similar properties to inflation with w < -1/3. At one stroke, this shows how the model is different from inflation and why it may work just as well as inflation in resolving cosmological problems.

  12. Deformation and fatigue behaviors of carburized automotive gear steel and predictions

    Directory of Open Access Journals (Sweden)

    Bonglae Jo

    2016-07-01

    Full Text Available The fatigue behavior of carburized components such as automotive transmission gears is very complex due to hardness and microstructure difference, residual stresses and multi-axial stress states developed between the case and the core. In addition, automotive gears in service, commonly used in helical type, are actually subjected to complex stress conditions such as bending, torsion, and contact stress states. This study presents experimental and analytical results on deformation behavior of carburized steels, widely used in automotive gears, under cyclic stress conditions including axial and torsion loadings. Axial fatigue tests and rotating bending fatigue tests are also included. Predictions of cyclic deformation and fatigue behaviors of the carburized steel with two-layer model are compared with experimental results. The carburized steel investigated in this study exhibited cyclic softening under both axial loading and torsional loading. Predicted results with simple two-layer model for the cyclic deformation and fatigue behaviors were comparatively similar to the experimental data.

  13. Diagnosis of Cyclic Vomiting

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2002-12-01

    Full Text Available In a study at Children’s Hospital, Ann Arbor, MI, and Children’s Memorial Hospital, Chicago, designed primarily to compare cost-effectiveness of three methods of management of cyclic vomiting cases, one group of patients received an extensive diagnostic evaluation, a second was treated with empiric antimigraine drugs for 2 months, and a third an upper GI series with small-bowel follow-through (UGI-SBFT plus empiric therapy.

  14. Geometry of Cyclic Pursuit

    Science.gov (United States)

    2009-12-18

    analysis of the equilibria based on linearization of the shape dynamics. In [10], the authors extend their analysis to incorporate feedback control...differentiable curves in R2, deriving our dynamics from the natural Frenet frame equations (see, e.g., [5] for details). (A three- dimensional analysis of...cyclic pursuit formulated in terms of the natural Frenet frame equations is a topic of ongoing work.) As is depicted in figure 1, we let ri denote the

  15. Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits.

    Science.gov (United States)

    Zhao, Yu; Xiao, Ming; He, Wenbo; Cai, Zhiyou

    2015-01-01

    The cAMP response element binding protein (CREB) plays an important role in the mechanism of cognitive impairment and is also pivotal in the switch from short-term to long-term memory. Brain-derived neurotrophic factor (BDNF) seems a promising avenue in the treatment of cerebral ischemia injury since this neurotrophin could stimulate structural plasticity and repair cognitive impairment. Several findings have displayed that the dysregulation of the CREB-BDNF cascade has been involved in cognitive impairment. The aim of this study was to investigate the effect of cerebral ischemia on learning and memory as well as on the levels of CREB, phosphorylated CREB (pCREB), and BDNF, and to determine the effect of minocycline on CREB, pCREB, BDNF, and behavioral functional recovery after cerebral ischemia. The animal model was established by permanent bilateral occlusion of both common carotid arteries. Behavior was evaluated 5 days before decapitation with Morris water maze and open-field task. Four days after permanent bilateral occlusion of both common carotid arteries, minocycline was administered by douche via the stomach for 4 weeks. CREB and pCREB were examined by Western blotting, reverse transcription polymerase chain reaction, and immunohistochemistry. BDNF was measured by immunohistochemistry and Western blotting. The model rats after minocycline treatment swam shorter distances than control rats before finding the platform (P=0.0007). The number of times the platform position was crossed for sham-operation rats was more than that of the model groups in the corresponding platform location (P=0.0021). The number of times the platform position was crossed for minocycline treatment animals was significantly increased compared to the model groups in the corresponding platform position (P=0.0016). CREB, pCREB, and BDNF were downregulated after permanent bilateral occlusion of both common carotid arteries in the model group. Minocycline increased the expression of CREB

  16. Dravet syndrome with favourable cognitive and behavioral development due to a novel SCN1A frameshift mutation.

    Science.gov (United States)

    Jiang, Peifang; Shen, Jue; Yu, Yonglin; Jiang, Lihua; Xu, Jialu; Xu, Lu; Yu, Huimin; Gao, Feng

    2016-07-01

    Children with Dravet syndrome (DS) often have severe cognitive, behaviour and motor impairments. Patients with truncating mutations would logically have the more severe phenotype. Here we present a case of DS with an unusually favourable cognitive and behavioral development with a novel SCN1A frameshift mutation (c.4233-4234insAT). Under regular following up for ten years, the patient had normal expressive language and mild motor clumsiness. It is suggested that besides the type of SCN1A mutation, other mechanisms may be existed to influence the SCN1A phenotype, such as modifier genes, developmental variability, accumulation of somatic mutation in lifetime and environmental insults can all contribute to the cognitive and behavioral outcome.

  17. Evidence that behavioral phenotypes of morphine in β-arr2-/- mice are due to the unmasking of JNK signaling.

    Science.gov (United States)

    Mittal, Nitish; Tan, Miao; Egbuta, Onyemachi; Desai, Nina; Crawford, Cynthia; Xie, Cui-Wei; Evans, Christopher; Walwyn, Wendy

    2012-07-01

    The altered behavioral effects of morphine, but not most other mu agonists, in mice lacking β-arrestin 2, suggest that this scaffolding protein regulates the signaling cascade of this commonly used analgesic. One of the cascades that could be regulated by β-arrestin 2 is cJun-N-terminal kinase (JNK), which binds with β-arrestin 2 and modulates the analgesic effects of morphine. Using neurons lacking β-arrestin 2 (β-arr2-/-) to examine this interaction, we found that β-arr2-/- neurons show altered intracellular distribution of JNK and cJun, and that morphine, but not fentanyl, increased the nuclear localization of the phosphorylated, therefore activated, form of cJun, a JNK target in dorsal root ganglia neurons. This suggests that deleting β-arrestin 2 affects the JNK cascade. We therefore examined whether some of the behavioral phenotypes of mice lacking β-arrestin 2 could be a result of altered JNK signaling. Indeed, two different JNK inhibitors reversed the enhanced analgesic effect of morphine, a known phenotype of β-arr2-/- mice, to +/+ levels. Both the reduced locomotor effect of morphine and the psychomotor sensitization to repeated morphine administration in β-arr2-/- mice were also returned to +/+ levels by inhibiting JNK. In contrast, the behavioral effects of fentanyl were neither genotype-dependent nor affected by JNK inhibition. Furthermore, a PKC inhibitor had a similar effect as inhibiting JNK in reducing the enhanced analgesic effect of morphine in β-arr2-/- mice to +/+ levels. In summary, removing β-arrestin 2 reveals mu receptor activation of the JNK cascade in a ligand-specific manner explaining several behavioral phenotypes of β-arr2-/- mice.

  18. Behavioral effects and somnolence due to levetiracetam versus oxcarbazepine - a retrospective comparison study of North Indian patients with refractory epilepsy.

    Science.gov (United States)

    Shukla, Garima; Gupta, Anupama; Agarwal, Priya; Poornima, Shivani

    2016-11-01

    Levetiracetam (LEV) is often chosen early in the treatment of refractory epilepsy; however, its adverse effects have largely been studied as part of clinical trials. Oxcarbazepine and valproate (VPA) are the other commonly used AEDs and, hence, serve as good comparators. This study was conducted to evaluate behavioral abnormalities and somnolence among patients with epilepsy being treated with LEV and/or OXC compared with those receiving VPA. Data of consecutive patients attending our intractable epilepsy clinic over a 2 1/2-year period were reviewed, and patients with at least one seizure a month, who had been initiated on either or a combination of LEV, VPA, or OXC, were included for analysis. Data regarding behavioral adverse effects, daytime somnolence (EDS), and weight changes were collected apart from those regarding any major effect necessitating dose reduction or discontinuation of the AED. Among a total of 445 patients screened, 292 (93 F, median age: 21years [range: 8-54]; 237 focal and 55 generalized epilepsy) fulfilled inclusion criteria. Median epilepsy duration was 11years. Levetiracetam had been introduced in 114 patients, VPA in 134, and OXC in 151 during the study period. Twenty-three were on LEV+OXC, 27 on LEV+VPA, and 33 on VPA+OXC. Behavioral disturbances (irritability, obsessive manifestations, aggressiveness, and frank psychosis) were observed in 43 patients; 23 on introduction of LEV (20.2%); LEV was discontinued in 10 (9%). Daytime somnolence was reported by 28 patients, 15 on OXC (10%); 8 received oral modafinil for the same, while none discontinued this AED. Only one patient on LEV and 3 on VPA reported EDS. Menstrual disturbances were reported by 9, weight gain by 3, and severe hair loss by 2 females on VPA. Behavioral disturbances with levetiracetam are common among patients with refractory epilepsy while somnolence is common with oxcarbazepine. Antiepileptic drugs should be selected with this in perspective. Copyright © 2016 Elsevier

  19. Changes of the hindgut microbiota due to high-starch diet can be associated with behavioral stress response in horses.

    Science.gov (United States)

    Destrez, Alexandra; Grimm, Pauline; Cézilly, Frank; Julliand, Véronique

    2015-10-01

    The digestive system of horses is adapted to a high-fiber diet consumed in small amounts over a long time. However, during training, high-starch and low-fiber diets are usually fed which may induce hindgut microbial disturbances and intestinal pain. These diets can be described as alimentary stress. The aim of the present study was to investigate to what extent changes in behavior are associated with alimentary stress and microbial composition changes of the cecal or colonic ecosystem. Six fistulated horses were used. The alimentary stress was a modification of diet from a high-fiber diet (100% hay) to a progressive low-fiber and high-starch diet (from 90% hay and 10% barley to 57% hay and 43% barley in 5 days). Cecal and colonic total anaerobic, cellulolytic, amylolytic and lactate-utilizing bacteria were enumerated three times (twice on high-fiber diet and once on 57% hay and 43% barley diet). The behavior of horses was assessed from continuous video recording over an 18-h time period. In addition two personality traits were measured: neophobia (assessed from the reaction to the presence of a novel object placed near a feeder in a test arena) and sociability (assessed from the reaction to an unfamiliar horse in a stall). Video recordings were analyzed by scan sampling every 10 min using the following behavioral categories: lying, resting, feeding and being vigilant. In addition, we recorded time spent feeding and time spent in vigilance during the neophobia test, and time spent in vigilance and time spent in interactions with the unfamiliar horse during the sociability test. The alimentary stress induced significant increases of colonic total anaerobic bacteria, lactate-utilizing bacteria and amylolytic bacteria concentrations. When horses were fed the 57% hay–43% barley diet, time spent in vigilance tended to be positively correlated with cecal and colonic amylolytic bacteria concentrations during the sociability test and with cecal lactate-utilizing and

  20. Martensitic Transformation in Ultrafine-Grained Stainless Steel AISI 304L Under Monotonic and Cyclic Loading

    Directory of Open Access Journals (Sweden)

    Heinz Werner Höppel

    2012-02-01

    Full Text Available The monotonic and cyclic deformation behavior of ultrafine-grained metastable austenitic steel AISI 304L, produced by severe plastic deformation, was investigated. Under monotonic loading, the martensitic phase transformation in the ultrafine-grained state is strongly favored. Under cyclic loading, the martensitic transformation behavior is similar to the coarse-grained condition, but the cyclic stress response is three times larger for the ultrafine-grained condition.

  1. Constitutive Model for Multiaxial Ratcheting Predictions of Cyclic Softening Weld Metal

    Institute of Scientific and Technical Information of China (English)

    GAO Hong; CHEN Xu; JIAO Rong

    2005-01-01

    A series of fully reversed axial, torsional strain-controlled cyclic tests and two multiaxial ratcheting tests were conducted on weld metal specimens using an Instron8521 tension-torsional servo-controlled testing machine. The weld metal showed clear cyclic softening under axial, torsional and multiaxial loading. A modified kinematic hardening rule was proposed in which a multiaxial-loading-dependent parameter incorporated the radial evanescence term of the Burlet-Cailletaud mode with the Ohno-Wang kinematic hardening rule to predict the multiaxial ratcheting effects. The introduction of yield stress evolved with accumulated plasticity strain enables the model to predict cyclic plasticity behavior of cyclic softening or cyclic hardening materials. Thus modified model considers the isotropic hardening as well as kinematic hardening of yield surface, and it can present description of plasticity behavior and ratcheting of cyclic softening and cyclic hardening materials well under multiaxial loading.

  2. Pendulating—A grounded theory explaining patients’ behavior shortly after having a leg amputated due to vascular disease

    Directory of Open Access Journals (Sweden)

    Ulla Riis Madsen

    2016-09-01

    Full Text Available Introduction: Although the group of vascular leg amputated patients constitutes some of the most vulnerable and frail on the orthopedic wards, previous research of amputated patients has focused on patients attending gait training in rehabilitation facilities leaving the patient experience shortly after surgery unexplored. Understanding patients’ behavior shortly after amputation could inform health professionals in regard to how these vulnerable patients’ needs at hospital can be met as well as how to plan for care post-discharge. Aim: To construct a grounded theory (GT explaining patients’ behavior shortly after having a leg amputated as a result of vascular disease. Method: In line with constructivist GT methodology, data from ethnographic observations and interviews were simultaneously collected and analyzed using the constant comparative method covering the patients’ experiences during the first 4 weeks post-surgery. Data collection was guided by theoretical sampling and comprised 11 patients. A GT was constructed. Results: Patients went through a three-phased process as they realized they were experiencing a life-changing event. The first phase was “Losing control” and comprised the sub-categories “Being overwhelmed” and “Facing dependency.” The second phase was “Digesting the shock” and comprised the sub-categories “Swallowing the life-changing decision,” “Detecting the amputated body” and “Struggling dualism.” The third phase was “Regaining control” and comprised the sub-categories “Managing consequences” and “Building-up hope and self-motivation.” “Pendulating” was identified as the core category describing the general pattern of behavior and illustrated how patients were swinging both cognitively and emotionally throughout the process. Conclusion: The theory of “Pendulating” offers a tool to understand the amputated patients’ behavior and underlying concerns and to recognize

  3. Pendulating—A grounded theory explaining patients’ behavior shortly after having a leg amputated due to vascular disease

    Science.gov (United States)

    Madsen, Ulla Riis; Hommel, Ami; Bååth, Carina; Berthelsen, Connie Bøttcher

    2016-01-01

    Introduction Although the group of vascular leg amputated patients constitutes some of the most vulnerable and frail on the orthopedic wards, previous research of amputated patients has focused on patients attending gait training in rehabilitation facilities leaving the patient experience shortly after surgery unexplored. Understanding patients’ behavior shortly after amputation could inform health professionals in regard to how these vulnerable patients’ needs at hospital can be met as well as how to plan for care post-discharge. Aim To construct a grounded theory (GT) explaining patients’ behavior shortly after having a leg amputated as a result of vascular disease. Method In line with constructivist GT methodology, data from ethnographic observations and interviews were simultaneously collected and analyzed using the constant comparative method covering the patients’ experiences during the first 4 weeks post-surgery. Data collection was guided by theoretical sampling and comprised 11 patients. A GT was constructed. Results Patients went through a three-phased process as they realized they were experiencing a life-changing event. The first phase was “Losing control” and comprised the sub-categories “Being overwhelmed” and “Facing dependency.” The second phase was “Digesting the shock” and comprised the sub-categories “Swallowing the life-changing decision,” “Detecting the amputated body” and “Struggling dualism.” The third phase was “Regaining control” and comprised the sub-categories “Managing consequences” and “Building-up hope and self-motivation.” “Pendulating” was identified as the core category describing the general pattern of behavior and illustrated how patients were swinging both cognitively and emotionally throughout the process. Conclusion The theory of “Pendulating” offers a tool to understand the amputated patients’ behavior and underlying concerns and to recognize where they are in the

  4. Natural variation in the thermotolerance of neural function and behavior due to a cGMP-dependent protein kinase.

    Directory of Open Access Journals (Sweden)

    Ken Dawson-Scully

    Full Text Available Although it is acknowledged that genetic variation contributes to individual differences in thermotolerance, the specific genes and pathways involved and how they are modulated by the environment remain poorly understood. We link natural variation in the thermotolerance of neural function and behavior in Drosophila melanogaster to the foraging gene (for, which encodes a cGMP-dependent protein kinase (PKG as well as to its downstream target, protein phosphatase 2A (PP2A. Genetic and pharmacological manipulations revealed that reduced PKG (or PP2A activity caused increased thermotolerance of synaptic transmission at the larval neuromuscular junction. Like synaptic transmission, feeding movements were preserved at higher temperatures in larvae with lower PKG levels. In a comparative assay, pharmacological manipulations altering thermotolerance in a central circuit of Locusta migratoria demonstrated conservation of this neuroprotective pathway. In this circuit, either the inhibition of PKG or PP2A induced robust thermotolerance of neural function. We suggest that PKG and therefore the polymorphism associated with the allelic variation in for may provide populations with natural variation in heat stress tolerance. for's function in behavior is conserved across most organisms, including ants, bees, nematodes, and mammals. PKG's role in thermotolerance may also apply to these and other species. Natural variation in thermotolerance arising from genes involved in the PKG pathway could impact the evolution of thermotolerance in natural populations.

  5. Supplementary Material for: The arabidopsis cyclic nucleotide interactome

    KAUST Repository

    Donaldson, Lara

    2016-01-01

    Abstract Background Cyclic nucleotides have been shown to play important signaling roles in many physiological processes in plants including photosynthesis and defence. Despite this, little is known about cyclic nucleotide-dependent signaling mechanisms in plants since the downstream target proteins remain unknown. This is largely due to the fact that bioinformatics searches fail to identify plant homologs of protein kinases and phosphodiesterases that are the main targets of cyclic nucleotides in animals. Methods An affinity purification technique was used to identify cyclic nucleotide binding proteins in Arabidopsis thaliana. The identified proteins were subjected to a computational analysis that included a sequence, transcriptional co-expression and functional annotation analysis in order to assess their potential role in plant cyclic nucleotide signaling. Results A total of twelve cyclic nucleotide binding proteins were identified experimentally including key enzymes in the Calvin cycle and photorespiration pathway. Importantly, eight of the twelve proteins were shown to contain putative cyclic nucleotide binding domains. Moreover, the identified proteins are post-translationally modified by nitric oxide, transcriptionally co-expressed and annotated to function in hydrogen peroxide signaling and the defence response. The activity of one of these proteins, GLYGOLATE OXIDASE 1, a photorespiratory enzyme that produces hydrogen peroxide in response to Pseudomonas, was shown to be repressed by a combination of cGMP and nitric oxide treatment. Conclusions We propose that the identified proteins function together as points of cross-talk between cyclic nucleotide, nitric oxide and reactive oxygen species signaling during the defence response.

  6. Ekpyrotic and Cyclic Cosmology

    CERN Document Server

    Lehners, Jean-Luc

    2008-01-01

    Ekpyrotic and cyclic cosmologies provide theories of the very early and of the very late universe. In these models, the big bang is described as a collision of branes - and thus the big bang is not the beginning of time. Before the big bang, there is an ekpyrotic phase with equation of state w=P/rho >> 1 (where P is the average pressure and rho the average energy density) during which the universe slowly contracts. This phase resolves the standard cosmological puzzles and generates a nearly scale-invariant spectrum of cosmological perturbations containing a significant non-gaussian component. At the same time it produces small-amplitude gravitational waves with a blue spectrum. The dark energy dominating the present-day cosmological evolution is reinterpreted as a small attractive force between our brane and a parallel one. This force eventually induces a new ekpyrotic phase and a new brane collision, leading to the idea of a cyclic universe. This review discusses the detailed properties of these models, thei...

  7. Ekpyrotic and cyclic cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Lehners, Jean-Luc [Princeton Center for Theoretical Science, Jadwin Hall, Princeton University, Princeton NJ 08544 (United States)], E-mail: jlehners@princeton.edu

    2008-09-15

    Ekpyrotic and cyclic cosmologies provide theories of the very early and of the very late universe. In these models, the big bang is described as a collision of branes - and thus the big bang is not the beginning of time. Before the big bang, there is an ekpyrotic phase with equation of state w=P/({rho}) >>1 (where P is the average pressure and {rho} the average energy density) during which the universe slowly contracts. This phase resolves the standard cosmological puzzles and generates a nearly scale-invariant spectrum of cosmological perturbations containing a significant non-Gaussian component. At the same time it produces small-amplitude gravitational waves with a blue spectrum. The dark energy dominating the present-day cosmological evolution is reinterpreted as a small attractive force between our brane and a parallel one. This force eventually induces a new ekpyrotic phase and a new brane collision, leading to the idea of a cyclic universe. This review discusses the detailed properties of these models, their embedding in M-theory and their viability, with an emphasis on open issues and observational signatures.

  8. [Asthma and cyclic neutropenia].

    Science.gov (United States)

    Salazar Cabrera, A N; Berrón Pérez, R; Ortega Martell, J A; Onuma Takane, E

    1996-01-01

    We report a male with history of recurrent infections (recurrent oral aphtous disease [ROAD], middle ear infections and pharyngo amigdalitis) every 3 weeks since he was 7 months old. At the age of 3 years cyclic neutropenia was diagnosed with cyclic fall in the total neutrophil count in blood smear every 21 days and prophylactic antimicrobial therapy was indicated. Episodic events every 3 weeks of acute asthma and allergic rhinitis were detected at the age of 6 years old and specific immunotherapy to Bermuda grass was given during 3 years with markedly improvement in his allergic condition but not in the ROAD. He came back until the age of 16 with episodic acute asthma and ROAD. The total neutrophil count failed to 0 every 21 days and surprisingly the total eosinophil count increased up to 2,000 at the same time, with elevation of serum IgE (412 Ul/mL). Specific immunotherapy to D.pt. and Aller.a. and therapy with timomodulin was indicated. After 3 months we observed clinical improvement in the asthmatic condition and the ROAD disappeared, but the total neutrophil count did not improve. We present this case as a rare association between 2 diseases with probably no etiological relationship but may be physiopatological that could help to understand more the pathogenesis of asthma.

  9. Cyclic Strain Enhances Cellular Uptake of Nanoparticles

    OpenAIRE

    Jia Hu; Yaling Liu

    2015-01-01

    Nanoparticles (NPs) have gained increasing interest in recent years due to their potential use as drug carrier, imaging, and diagnostic agents in pharmaceutical and biomedical applications. While many cells in vivo experience mechanical forces, little is known about the correlation of the mechanical stimulation and the internalization of NPs into cells. This paper investigates the effects of applied cyclic strain on NP uptake by cells. Bovine aortic endothelial cells (BAECs) were cultured on ...

  10. Supra-normal stimulation of dopamine D1 receptors in the prelimbic cortex blocks behavioral expression of both aversive and rewarding associative memories through a cyclic-AMP-dependent signaling pathway.

    Science.gov (United States)

    Lauzon, Nicole M; Bechard, Melanie; Ahmad, Tasha; Laviolette, Steven R

    2013-04-01

    Dopamine (DA) receptor transmission through either D(1) or D(2)-like subtypes is involved critically in the processing of emotional information within the medial prefrontal cortex (mPFC). However the functional role of specific DA D(1)-like receptor transmission in the expression of emotionally salient associative memories (either aversive or rewarding) is not currently understood. Here we demonstrate that specific activation of DA D(1) receptors in the prelimbic (PLC) division of the mPFC causes a transient block in the behavioral expression of both aversive and rewarding associative memories. We report that intra-PLC microinfusions of a selective D(1) receptor agonist block the spontaneous expression of an associative olfactory fear memory, without altering the stability of the original memory trace. Furthermore, using an unbiased place conditioning procedure (CPP), intra-PLC D(1) receptor activation blocks the spontaneous expression of an associative morphine (5 mg/kg; i.p.) reward memory, while leaving morphine-primed memory expression intact. Interestingly, both intra-PLC D(1)-receptor mediated block of either fear-related or reward-related associative memories were dependent upon downstream cyclic-AMP (cAMP) signaling as both effects were rescued by co-administration of a cAMP signaling inhibitor. The blockade of both rewarding and aversive associative memories is mediated through a D(1)-specific signaling pathway, as neither forms of spontaneous memory expression were blocked by intra-PLC microinfusions of a D(2)-like receptor agonist. Our results demonstrate that the spontaneous expression of either rewarding or aversive emotionally salient memories shares a common, D(1)-receptor mediated substrate within the mPFC.

  11. Fragmentations of protonated cyclic-glycylglycine and cyclic-alanylalanine

    NARCIS (Netherlands)

    Shek, P. Y. I.; Lau, J. K. C.; Zhao, J. F.; Grzetic, J.; Verkerk, U. H.; Oomens, J.; Hopkinson, A. C.; Siu, K. W. M.

    2012-01-01

    Collision-induced dissociation has been used to study the fragmentations of two protonated diketopiperazines, protonated cyclic-glycylglycine and cyclic-alanylalanine. Protonated cyclo-AA lost CO and (CO + NH3) at low collision energies, channels attributed to dissociation of the O-protonated

  12. Cosmic Perturbations Through the Cyclic Ages

    CERN Document Server

    Erickson, J K; Steinhardt, P J; Turok, N G; Erickson, Joel K.; Gratton, Steven; Steinhardt, Paul J.; Turok, Neil

    2006-01-01

    We analyze the evolution of cosmological perturbations in the cyclic model, paying particular attention to their behavior and interplay over multiple cycles. Our key results are: (1) galaxies and large scale structure present in one cycle are generated by the quantum fluctuations in the preceding cycle without interference from perturbations or structure generated in earlier cycles and without interfering with structure generated in later cycles; (2) the ekpyrotic phase, an epoch of gentle contraction with equation of state $w\\gg 1$ preceding the hot big bang, makes the universe homogeneous, isotropic and flat within any given observer's horizon; and, (3) although the universe is uniform within each observer's horizon, the global structure of the cyclic universe is more complex, owing to the effects of superhorizon length perturbations, and cannot be described in a uniform Friedmann-Robertson-Walker picture. In particular, we show that the ekpyrotic phase is so effective in smoothing, flattening and isotropiz...

  13. Early cognitive changes due to whole body γ-irradiation: a behavioral and diffusion tensor imaging study in mice.

    Science.gov (United States)

    Kumar, Mayank; Haridas, Seenu; Trivedi, Richa; Khushu, Subhash; Manda, Kailash

    2013-10-01

    Radiation-induced aberration in the neuronal integrity and cognitive functions are well known. However, there is a lacuna between sparsely reported immediate effects and the well documented delayed effects of radiation on cognitive functions. The present study was aimed at investigating the radiation-dose dependent incongruities in the early cognitive changes, employing two approaches, behavioral functions and diffusion tensor imaging (DTI). Six-month old female C57BL/6 mice were exposed to whole-body doses of 2, 5 and 8 Gy of γ-radiation and 24 h after exposure, the stress and anxiety levels were examined in the open-field test (OFT). Forty-eight hours after irradiation, the hippocampal dependent recognition memory was observed by the novel object recognition task (NORT), and the cognitive functions related to memory processing and recall were tested using the elevated plus maze (EPM). Magnetic resonance imaging, including diffusion tensor imaging (DTI) was done at 48-hour post-irradiation to visualize microstructural damage in brain parenchyma. Our results indicate a complex dose independent effect on the cognitive functions immediately after exposure to gamma rays. Radiation exposure caused short-term memory dysfunctions at lower doses, which were seen to be abrogated at higher doses, but the long-term memory processing was disrupted at higher doses. The hippocampus emerged as one of the sensitive regions to be affected by whole-body exposure to gamma rays, which led to profound immediate alterations in cognitive functions. Furthermore, the results indicate a cognitive recovery process, which might be dependent on the extent of damage to the hippocampal region. The present study also emphasizes the importance of further research to unravel the complex pattern of neurobehavioral responses immediately following ionizing radiation exposure. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Mean field dynamics of the coexistence phase in generalized cyclic competitions

    Science.gov (United States)

    Mowlaei, Shahir; Roman, Ahmed; Pleimling, Michel

    2014-03-01

    Multispecies Lotka-Volterra models have been a rich source of inspiration in multidisciplinary areas of research due to their inherent nonlinearity which yields intriguing and complex behavior for a large class of competition schemes. Of particular interest here is a subclass of these models where competition is realized in a cyclic manner through a variety of reactions. The goal is to predict and quantify emerging two-dimensional patterns in the coexistence regime. The focus will further be on a set of models that can be analyzed without using the cumbersome machinery of slow-manifolds. This work is supported by the US National Science Foundation through grant DMR-1205309.

  15. Small-Scale Testing Rig for Long-Term Cyclically Loaded Monopiles in Cohesionless Soil

    DEFF Research Database (Denmark)

    Roesen, Hanne Ravn; Ibsen, Lars Bo; Andersen, Lars Vabbersgaard

    2012-01-01

    Monopiles used as foundations for offshore wind turbines are exposed to strong cyclic loading due to the wind and wave forces. This cyclic loading may induce an accumulated rotation and a change in stiffness with time depending on the mean level (i.e. the static loading), the amplitude, and the p......Monopiles used as foundations for offshore wind turbines are exposed to strong cyclic loading due to the wind and wave forces. This cyclic loading may induce an accumulated rotation and a change in stiffness with time depending on the mean level (i.e. the static loading), the amplitude......, and the period of the cyclic loading. However, the design guidance on these issues is limited. Thus, in order to investigate the pile behaviour for cyclically long-term loaded monopiles, a test setup for small-scale tests in saturated dense cohesionless soil is constructed and presented in here. The cyclic...

  16. Gold prices: Analyzing its cyclical behavior

    Directory of Open Access Journals (Sweden)

    Martha Gutiérrez

    2013-01-01

    Full Text Available El oro es un bien básico que se ve como refugio cuando una crisis financiera acontece; pero cuando los mercados de valores son prósperos, las acciones son una alternativa más atractiva, y así se da el ciclo del oro. El DJIA/GF (relación entre el Índice Industrial Dow Jones y el precio del oro permite establecer la evolución de los precios del oro en relación con el NYSE. Este trabajo tiene dos objetivos: demostrar que la relación DJIA/ GF es fuertemente cíclica usando análisis de Fourier, y establecer un modelo de redes neuronales para predecir el comportamiento de esta relación durante 2011-2020. Para ello, eventos económicos cíclicos como la Gran Depresión junto con la crisis de los años 70, y el auge de los años 50 junto con la recuperación de los 90, se contrastan a la luz de la relación DJIA/GF. Se encuentra que los precios del oro evolucionan cíclicamente con un periodo dominante de 37 años y están afectados principalmente por los precios de los energéticos, los mercados financieros e indicadores macroeconómicos.

  17. 开口冷弯厚壁型钢轴压构件抗震性能研究%Research on the seismic behaviors of opening cold-formed thick-walled steel under the axial cyclic loading

    Institute of Scientific and Technical Information of China (English)

    付小超; 李元齐; 沈祖炎

    2016-01-01

    为研究开口冷弯厚壁型钢构件在轴向滞回荷载作用下的抗震性能,首先选取了3根壁厚t>6 mm的冷弯内卷边槽钢进行轴向滞回试验,然后建立相关的ANSYS有限元模型进行模拟计算,在与试验结果对比的基础上,选取了不同的腹板宽厚比(h/t=25~90)、绕弱轴长细比(λy=30~90)的构件进行参数化分析计算.研究结果表明:宽厚比、长细比是影响冷弯型钢抗震性能的两个主要因素,宽厚比(h/t)越大抗震性能越差,长细比(λy)越大抗震性能同样也越差,设计时应尽量避免选择长细比和宽厚比均较大的构件.%In order to investigate the hysteretic behaviors of opening cold-formed thick-walled steel members under the axial cyclic loading, three cold-formed steel columns were tested. On the basis of compared with the test results, a finite element method ( FEM) in ANSYS was established. The in-fluence of width-thickness ratio ( h/t) rang from 25 to 90 for web and slenderness ratio about the weak axis y (λy ) rang from 30 to 90 of such members were investigated by FEM. Analysis results in-dicated that the width-thickness ratio and the slenderness ratio about the weak axis y are the most important factors to affect the hysteretic behaviors. So, the cold-formed steels which with great width-thickness ratio ( h/t) and great slenderness ratio (λy ) should be avoided in designing, because they will lead to poor seismic performance.

  18. Cyclic cohomology of Hopf algebras

    NARCIS (Netherlands)

    Crainic, M.

    2001-01-01

    We give a construction of ConnesMoscovicis cyclic cohomology for any Hopf algebra equipped with a character Furthermore we introduce a noncommutative Weil complex which connects the work of Gelfand and Smirnov with cyclic cohomology We show how the Weil complex arises naturally when looking at Hopf

  19. Biosynthesis and characterization of cadmium sulfide nanoparticles – An emphasis of zeta potential behavior due to capping

    Energy Technology Data Exchange (ETDEWEB)

    Sankhla, Aryan, E-mail: aaryansankhla@gmail.com [Centre for Converging Technologies, University of Rajasthan, Jaipur, 302015 (India); Sharma, Rajeshwar; Yadav, Raghvendra Singh [Centre for Converging Technologies, University of Rajasthan, Jaipur, 302015 (India); Kashyap, Diwakar [Department of Biological Chemistry, Ariel University, Ariel, 40700 (Israel); Kothari, S.L. [Institute of Biotechnology, Amity University, Jaipur, 303002 (India); Kachhwaha, S. [Department of Botany, University of Rajasthan, Jaipur, 302004 (India)

    2016-02-15

    and diameter well below 10 nm. • Proteins play active roles in the formation and in capping of CdS NPs as confirmed. • High ζ-potential with varying pH confers stability of aqueous CdS NP dispersion. • Dispersion stability due to interplay between NP surface and adsorbed protein.

  20. Effect of confining pressure due to external jacket of steel plate or shape memory alloy wire on bond behavior between concrete and steel reinforcing bars.

    Science.gov (United States)

    Choi, Eunsoo; Kim, Dongkyun; Park, Kyoungsoo

    2014-12-01

    For external jackets of reinforced concrete columns, shape memory alloy (SMA) wires are easy to install, and they provide active and passive confining pressure; steel plates, on the other hand, only provide passive confining pressure, and their installation on concrete is not convenient because of the requirement of a special device. To investigate how SMA wires distinctly impact bond behavior compared with steel plates, this study conducted push-out bond tests of steel reinforcing bars embedded in concrete confined by SMA wires or steel plates. For this purpose, concrete cylinders were prepared with dimensions of 100 mm x 200 mm, and D-22 reinforcing bars were embedded at the center of the concrete cylinders. External jackets of 1.0 mm and 1.5 mm thickness steel plates were used to wrap the concrete cylinders. Additionally, NiTiNb SMA wire with a diameter of 1.0 mm was wound around the concrete cylinders. Slip of the reinforcing bars due to pushing force was measured by using a displacement transducer, while the circumferential deformation of specimens was obtained by using an extensometer. The circumferential deformation was used to calculate the circumferential strains of the specimens. This study assessed the radial confining pressure due to the external jackets on the reinforcing bars at bond strength from bond stress-slip curves and bond stress-circumferential strain curves. Then, the effects of the radial confining pressure on the bond behavior of concrete are investigated, and an equation is suggested to estimate bond strength using the radial confining pressure. Finally, this study focused on how active confining pressure due to recovery stress of the SMA wires influences bond behavior.

  1. Determination of behavioral reactions of a child of 3-6 ages group to be hospitalized due to an acute illness

    Directory of Open Access Journals (Sweden)

    Zümrüt Başbakkal

    2010-02-01

    Full Text Available The study is executed with mothers of children aged 3-6 (n=170 whose children were hospitalized for the first time between the dates of 15.07.2003 and 15.06.2006, who were reachable by phone and accepted to participate in the study aiming determination of behavioral reactions of a child of 3-6 ages group to be hospitalized due to an acute illness.In this study, for data gathering "Personal Information Form" including 15 questions and "Inquiry Form of Behavior Changes of  3-6 Ages Group Children After Being Hospitalized" with 30 questions were used. Date gathering forms were carried out as pre-test by using face-to-face interview method with mothers of 3-6 aged children who were hospitalized for the first time and were in first 12 hours of hospitalization. "Inquiry Form of Behavior Changes of 3-6 Ages Group Children After Being Hospitalized" was re-carried out with mothers by phone 1 month after children being discharged from hospital.In analyzing of datas statistical programme of SPSS 13.0 for Windows was used. In statistical evaluation;  number-percent dispersion, Wilcoxon Sing Rank test and Paired Sample-t test were used.According to the results obtained from the study, 57.6% of children are male with age average of 4,46±1,18 and 52.3% of them were hospitalized due to Gastroentestinal System Illnesses. A significant difference was determined between average points of behavior changes of 3-6 ages group children hospitalized due to an acute illness before hospitalized (10,735±4,882 and after being discharged from hospital (15,0476±4,306. In the study, it is observed that there are some behavioral changes in children after being hospitalized such as being cranky before going to bed and during eating, disquiet, bed-wetting, seperation anxiety, excessive attachment to a parent, to need help even for the things he/she could accomplish, to have fear from new environments, people or objects, bad temper attacks, fear of doctor/nurse and hospital

  2. Mechanical behavior of PMMA due to artificial aging by means of a xenon-test chamber; Comportamiento mecanico del polimetilmetacrilato sometido a envejecimiento artificial mediante camara xenotest

    Energy Technology Data Exchange (ETDEWEB)

    Colom, X.; Nogues, F.; Valldeperas, J.; Carrillo, F.; Gordillo, A.

    2001-07-01

    In this investigation, the mechanical behavior of poly(methylmethacrylate) due to aging in Xenon test chamber, using a xenon-arch lamp as alight radiation to simulate natural sun light has been studied. This work studies the mechanical properties (elongation at break, Young's modules, tensile strength and toughness) of PMMA samples exposed to different aging conditions (until 1560 h xenotest that correspond to 750 days exposure at natural light). The evolution of different mechanical properties characterizes the PMMA's process of degradation. (Author) 10 refs.

  3. Cyclic sieving, promotion, and representation theory

    CERN Document Server

    Rhoades, Brendon

    2010-01-01

    We prove a collection of conjectures of D. White \\cite{WComm}, as well as some related conjectures of Abuzzahab-Korson-Li-Meyer \\cite{AKLM} and of Reiner and White \\cite{ReinerComm}, \\cite{WComm}, regarding the cyclic sieving phenomenon of Reiner, Stanton, and White \\cite{RSWCSP} as it applies to jeu-de-taquin promotion on rectangular tableaux. To do this, we use Kazhdan-Lusztig theory and a characterization of the dual canonical basis of $\\mathbb{C}[x_{11}, ..., x_{nn}]$ due to Skandera \\cite{SkanNNDCB}. Afterwards, we extend our results to analyzing the fixed points of a dihedral action on rectangular tableaux generated by promotion and evacuation, suggesting a possible sieving phenomenon for dihedral groups. Finally, we give applications of this theory to cyclic sieving phenomena involving reduced words for the long elements of hyperoctohedral groups and noncrossing partitions.

  4. An experimental study on the hysteretic behavior of composite steel staggered truss structures under cyclic load%循环荷载作用下混合式钢交错桁架结构的滞回性能试验研究

    Institute of Scientific and Technical Information of China (English)

    冉红东; 苏明周; 胡天兵; 申林

    2009-01-01

    通过1个5层混合式钢交错桁架结构1/3缩尺模型试验,研究该结构体系在循环荷载作用下的抗震性能和破坏机理.从滞回性能、刚度退化、结构延性、吸能能力及破坏模式等方面评价该结构体系的抗震性能.试验及分析结果表明,该结构体系具有承载能力高、侧向刚度大等优点,但其延性、变形能力和耗能能力较差,且侧向刚度沿结构高度方向分布不均匀.应力测试结果表明,该结构体系塑性铰开始形成于底部2层桁架,然后向上层桁架发展,直至试件形成机构破坏,柱中未形成塑性铰,地震能量主要通过桁架构件耗散,其破坏属于梁铰机制.%The seismic behavior and failure mechanism of steel staggered truss structures, including the hysteretic behavior, rigidity degeneration, ductility and energy dissipation, under cyclic load were studied through a 1/3 scaled model test. The results indicated that composite steel staggered truss structures are advantageous in bearing capacity, lateral rigidity, while the disadvantages are in ductility, deformability, energy dissipation and non-uniform lateral rigidity along the height. The stress measurement showed that the plastic hinge first formed in the members of the truss in the second story, and then extended to upper stories, and the structure failed due to the formation of the mechanism. The plastic hinges did not form in the column until model failure, earthquake energy was mostly dissipated by the truss members, and failure of composite steel staggered truss structures was due to formation of beam hinges.

  5. Temperature Dependent Cyclic Deformation Mechanisms in Haynes 188 Superalloy

    Science.gov (United States)

    Rao, K. Bhanu Sankara; Castelli, Michael G.; Allen, Gorden P.; Ellis, John R.

    1995-01-01

    The cyclic deformation behavior of a wrought cobalt-base superalloy, Haynes 188, has been investigated over a range of temperatures between 25 and 1000 C under isothermal and in-phase thermomechanical fatigue (TMF) conditions. Constant mechanical strain rates (epsilon-dot) of 10(exp -3)/s and 10(exp -4)/s were examined with a fully reversed strain range of 0.8%. Particular attention was given to the effects of dynamic strain aging (DSA) on the stress-strain response and low cycle fatigue life. A correlation between cyclic deformation behavior and microstructural substructure was made through detailed transmission electron microscopy. Although DSA was found to occur over a wide temperature range between approximately 300 and 750 C the microstructural characteristics and the deformation mechanisms responsible for DSA varied considerably and were dependent upon temperature. In general, the operation of DSA processes led to a maximum of the cyclic stress amplitude at 650 C and was accompanied by pronounced planar slip, relatively high dislocation density, and the generation of stacking faults. DSA was evidenced through a combination of phenomena, including serrated yielding, an inverse dependence of the maximum cyclic hardening with epsilon-dot, and an instantaneous inverse epsilon-dot sensitivity verified by specialized epsilon-dot -change tests. The TMF cyclic hardening behavior of the alloy appeared to be dictated by the substructural changes occuring at the maximum temperature in the TMF cycle.

  6. Magnetic interactions in CuII-LnIII cyclic tetranuclear complexes: is it possible to explain the occurrence of SMM behavior in CuII-TbIII and CuII-DyIII complexes?

    Science.gov (United States)

    Hamamatsu, Takefumi; Yabe, Kazuya; Towatari, Masaaki; Osa, Shutaro; Matsumoto, Naohide; Re, Nazzareno; Pochaba, Andrzej; Mrozinski, Jerzy; Gallani, Jean-Louis; Barla, Alessandro; Imperia, Paolo; Paulsen, Carley; Kappler, Jean-Paul

    2007-05-28

    An extensive series of tetranuclear CuII2LnIII2 complexes [CuIILLnIII(hfac)2]2 (with LnIII being all lanthanide(III) ions except for the radioactive PmIII) has been prepared in order to investigate the nature of the CuII-LnIII magnetic interactions and to try to answer the following question: What makes the CuII2TbIII2 and CuII2DyIII2 complexes single molecule magnets while the other complexes are not? All the complexes within this series possess a similar cyclic tetranuclear structure, in which the CuII and LnIII ions are arrayed alternately via bridges of ligand complex (CuIIL). Regular SQUID magnetometry measurements have been performed on the series. The temperature-dependent magnetic susceptibilities from 2 to 300 K and the field-dependent magnetizations from 0 to 5 T at 2 K have been measured for the CuII2LnIII2 and NiII2LnIII2 complexes, with the NiII2LnIII2 complex containing diamagnetic NiII ions being used as a reference for the evaluation of the CuII-LnIII magnetic interactions. These measurements have revealed that the interactions between CuII and LnIII ions are very weakly antiferromagnetic if Ln=Ce, Nd, Sm, Yb, ferromagnetic if Ln=Gd, Tb, Dy, Ho, Er, Tm, and negligible if Ln=La, Eu, Pr, Lu. With the same goal of better understanding the evolution of the intramolecular magnetic interactions, X-ray magnetic circular dichroism (XMCD) has also been measured on CuII2TbIII2, CuII2DyIII2, and NiII2TbIII2 complexes, either at the L- and M-edges of the metal ions or at the K-edge of the N and O atoms. Last, the CuII2TbIII2 complex exhibiting SMM behavior has received a closer examination of its low temperature magnetic properties down to 0.1 K. These particular measurements have revealed the unusual very slow setting-up of a 3D order below 0.6 K.

  7. Cyclic $n$-gonal Surfaces

    CERN Document Server

    Broughton, S Allen

    2010-01-01

    A cyclic $n$-gonal surface is a compact Riemann surface $X$ of genus $g\\geq 2$ admitting a cyclic group of conformal automorphisms $C$ of order $n$ such that the quotient space $X/C$ has genus 0. In this paper, we provide an overview of ongoing research into automorphism groups of cyclic $n$-gonal surfaces. Much of the paper is expository or will appear in forthcoming papers, so proofs are usually omitted. Numerous explicit examples are presented illustrating the computational methods currently being used to study these surfaces.

  8. Prognosis of Cyclic Vomiting Syndrome

    Directory of Open Access Journals (Sweden)

    J. Gordon Millichap

    2016-03-01

    Full Text Available Investigators from Teikyo University School of Medicine, Tokyo, Japan, evaluated the clinical features, prognosis, and prophylaxis of cyclic vomiting syndrome and the relationship between the syndrome and levels of adrenocorticotropic/antidiuretic hormones (ACTH/ADH.

  9. Design of a cyclic multiverse

    National Research Council Canada - National Science Library

    Piao, Yun-Song

    2010-01-01

    Recently, it has been noticed that the amplification of the amplitude of curvature perturbation cycle by cycle can lead to a cyclic multiverse scenario, in which the number of universes increases cycle by cycle...

  10. Algebraic curves of maximal cyclicity

    Science.gov (United States)

    Caubergh, Magdalena; Dumortier, Freddy

    2006-01-01

    The paper deals with analytic families of planar vector fields, studying methods to detect the cyclicity of a non-isolated closed orbit, i.e. the maximum number of limit cycles that can locally bifurcate from it. It is known that this multi-parameter problem can be reduced to a single-parameter one, in the sense that there exist analytic curves in parameter space along which the maximal cyclicity can be attained. In that case one speaks about a maximal cyclicity curve (mcc) in case only the number is considered and of a maximal multiplicity curve (mmc) in case the multiplicity is also taken into account. In view of obtaining efficient algorithms for detecting the cyclicity, we investigate whether such mcc or mmc can be algebraic or even linear depending on certain general properties of the families or of their associated Bautin ideal. In any case by well chosen examples we show that prudence is appropriate.

  11. Experimental Study on the Uniaxial Cyclic Deformation of 25CDV4.11 Steel

    Institute of Scientific and Technical Information of China (English)

    Guozheng KANG; Qianhua KAN; Juan ZHANG

    2005-01-01

    The strain cyclic characteristics and ratcheting behavior of 25CDV4.11 steel were studied by the experiments under uniaxial cyclic loading with relatively high cyclic number and at room temperature. The cyclic hardening/softening feature of the material was first observed under the uniaxial strain cycling with various strain amplitudes. Then, the ratcheting behavior of the material was researched in detail, and the effects of stress amplitude and mean stress on the ratcheting were discussed under uniaxial asymmetrical stress cycling. Comparing with the experimental results of SS316L stainless steel, it is concluded that the material exhibits remarkable cyclic softening feature, and then a special ratcheting behavior is caused. Some conclusions useful to establish corresponding constitutive model are obtained.

  12. Experimental study of the shearing behavior of cold-formed steel wall panels under cyclic load%冷弯薄壁型钢组合墙体循环荷载下抗剪性能试验研究

    Institute of Scientific and Technical Information of China (English)

    苏明周; 黄智光; 孙健; 齐岩; 申林

    2011-01-01

    为考察冷弯薄壁型钢组合墙体在循环荷载下的抗剪性能,进行10片足尺墙体试件水平低周反复加载试验,得到不同构造墙体的屈服荷载、最大荷载、破坏荷载、耗能系数和延性系数等性能指标。试验结果表明:组合墙体的耗能能力较好;墙体的抗剪承载力主要来源于墙板的蒙皮作用;斜撑对提高单柱墙体抗剪承载力起一定作用,但对双柱墙体的作用很小;当忽略墙体开洞部分的抗剪承载力后,单位长度开洞墙体的抗剪承载力比普通墙体稍高,表明墙体开洞部分承担了一定剪力;双柱墙体比单柱墙体的抗剪承载力显著提高;试验过程中各试件立柱的应变反应普遍较大、横撑%In order to study the shearing behavior of cold-formed steel wall panels, full scale model test was carried out for 10 pieces of wall panels under cyclic horizontal load. The shearing performance indexes of wall panels such as yield load, maximum load, failure load, energy dissipation coefficient, and ductility factor were calculated using the test results. Based on the analysis, the following conclusions are obtained. The wall panels had good energy dissipation capacity. The shear resistance of the wall panels mainly derived from skin action. The diagonal bracings were helpful to improve the shear resistance of single-column wall panel while nearly useless to double-column wall panel. The per unit shear resistance of wall panel with openings was higher than that of ordinary wall panel when the shear load carrying capacity of openings was ignored. The shear load carrying capacities of double-column wall panels were obviously higher than that of single-column ones. The strain response was largest for the column, smaller for the transverse bracing, and smallest for the diagonal bracing. The interface slip between the upper and lower wallboards was obvious, thus the seams between wallboards should be as small as possible

  13. Cyclic Cushing's syndrome: an overview.

    Science.gov (United States)

    Albiger, Nora Maria Elvira; Scaroni, Carla M; Mantero, Franco

    2007-11-01

    Cyclic Cushing's syndrome (CS) is a disorder in which glucocorticoid levels are alternately normal and high, the latter occurring in episodes that can last from a few days to several months. It is more common in children than in adults. Cyclic CS may be either of the two different forms of CS (ACTH-dependent or -independent CS). Clinically, it may present with one or many symptoms, depending on the duration of disease activity and the timing of the fluctuations. A serotoninergic influence, cyclic changes in central dopaminergic tone, spontaneous episodic hemorrhage in the tumor, and the action of inflammatory cytokines with antitumor properties are some of the mechanisms suggested to explain the physiopathology of this phenomenon but the exact mechanism remains to be clarified. The cyclic pattern of hypercortisolism can delay the final diagnosis of CS and make it difficult to interpret the results of dynamic tests. Patients may have paradoxical responses to dexamethasone that can reflect increasing or decreasing levels of endogenous activity. Hormone assessments have to be repeated periodically when a diagnosis of CS is suspected. The cyclic pattern can also interfere with medical treatment because patients may show unexpected clinical and biochemical signs of hypocortisolism when cortisol secretion cyclically returns to normal, so an accurate follow-up is mandatory in these patients.

  14. Temporal analysis of static priority preemptive scheduled cyclic streaming applications using CSDF models

    NARCIS (Netherlands)

    Kurtin, Philip Sebastian; Bekooij, Marco Jan Gerrit

    2016-01-01

    Real-time streaming applications with cyclic data dependencies that are executed on multiprocessor systems with processor sharing usually require a temporal analysis to give guarantees on their temporal behavior at design time. Current accurate analysis techniques for cyclic applications that are

  15. Transitive oriented 3-Hypergraphs of cyclic orders

    OpenAIRE

    2012-01-01

    In this paper we introduce the definition of transitivity for oriented 3-hypergraphs in order to study partial and complete cyclic orders. This definition allow us to give sufficient conditions on a partial cyclic order to be totally extendable. Furthermore, we introduce the 3-hypergraph associated to a cyclic permutation and characterize it in terms of cyclic comparability 3-hypergraphs.

  16. ACTH, cyclic nucleotides, and brain protein phosphorylation in vitro

    NARCIS (Netherlands)

    Zwiers, H; Veldhuis, H D; Schotman, P; Gispen, W H

    1976-01-01

    Endogenous phosphorylation of proteins from rat brain synaptosomal plasma membranes was studied in vitro. Cyclic AMP (cAMP) markedly stimulated(32)P incorporation in three protein bands with molecular weights of 75,000, 57,000, and 54,000, respectively. The effect of the behaviorally active peptide

  17. Challenges related to flotation cleaning of oil shales. Issues due to compositional and surface features and post-grinding surface behavior

    Directory of Open Access Journals (Sweden)

    Altun N. Emre

    2016-01-01

    Full Text Available Oil shale is an important energy resource alternative. Despite its recognition as an unconventional oil source, oil shale is also considered as an important solid fossil fuel alternative to coal and lignites due to the solid form and remarkable extent of organic content. Utilization possibilites, similar to coal and lignites, have been considered in the past decades and direct use of oil shales in thermal power production has been possible in countries like Estonia and China. In the perspective of utilization of oil shales in a similar manner to coal and lignites, problems and restrictions related to the inorganic ash-making and potentially pollutant constituents are applied. In this respect, cleaning of this important energy source through mineral processing methods, particularly by flotation, is an outstanding option. However, on the basis of unique features and distinctive characteristics, treatment of oil shales like a type of coal is a big perception and may be highly misleading. This paper discusses specific challenges regarding flotation behavior of oil shales with reference to the surface characteristics and behavior of oil shale entities – probably the most important aspect that determines the efficiency and success of the flotation based cleaning process.

  18. Mental and Behavioral Disorders Due to Substance Abuse and Perinatal Outcomes: A Study Based on Linked Population Data in New South Wales, Australia

    Directory of Open Access Journals (Sweden)

    Michelle R. Bonello

    2014-05-01

    Full Text Available Background: The effects of mental and behavioral disorders (MBD due to substance use during peri-conception and pregnancy on perinatal outcomes are unclear. The adverse perinatal outcomes of primiparous mothers admitted to hospital with MBD due to substance use before and/or during pregnancy were investigated. Method: This study linked birth and hospital records in NSW, Australia. Subjects included primiparous mothers admitted to hospital for MBD due to use of alcohol, opioids or cannabinoids during peri-conception and pregnancy. Results: There were 304 primiparous mothers admitted to hospital for MBD due to alcohol use (MBDA, 306 for MBD due to opioids use (MBDO and 497 for MBD due to cannabinoids (MBDC between the 12 months peri-conception and the end of pregnancy. Primiparous mothers admitted to hospital for MBDA during pregnancy or during both peri-conception and pregnancy were significantly more likely to give birth to a baby of low birthweight (AOR = 4.03, 95%CI: 1.97–8.24 for pregnancy; AOR = 9.21, 95%CI: 3.76–22.57 both periods; preterm birth (AOR = 3.26, 95% CI: 1.52–6.97 for pregnancy; AOR = 4.06, 95%CI: 1.50–11.01 both periods and admission to SCN or NICU (AOR = 2.42, 95%CI: 1.31–4.49 for pregnancy; AOR = 4.03, 95%CI: 1.72–9.44 both periods. Primiparous mothers admitted to hospital for MBDO, MBDC or a combined diagnosis were almost three times as likely to give birth to preterm babies compared to mothers without hospital admissions for psychiatric or substance use disorders. Babies whose mothers were admitted to hospital with MBDO before and/or during pregnancy were six times more likely to be admitted to SCN or NICU (AOR = 6.29, 95%CI: 4.62–8.57. Conclusion: Consumption of alcohol, opioids or cannabinoids during peri-conception or pregnancy significantly increased the risk of adverse perinatal outcomes.

  19. POSTBUCKLING OF CARBON NANOTUBES SUBJECTED TO CYCLIC LOAD

    Institute of Scientific and Technical Information of China (English)

    WangLifeng; HuHaiyan; GuoWanlin

    2005-01-01

    This study focuses on the postbuckling and the nonlinear behavior of single-walled carbon nanotubes subject to a cyclic axial compressive load through the use of molecular dynamic simulation based on the Tersoff-Brenner potential. It reveals the bifurcation behavior in the buckling process simulated with very fine time steps. In the whole cycle of nonlinear deformation, the carbon nanotubes exhibit the profound hysteretic behavior and the energy absorption ability. The molecular dynamics simulation indicates that the carbon nanotube behaves approximately as an ideal plastic spring when the cyclic strain is applied within the same postbuckling mode. In comparison, the theory of continuum mechanics gives a good prediction about the critical buckling strength, but only provides a rough estimation for the post-buckling behaviors.

  20. Prediction of cyclic delamination lives of plasma-sprayed hydroxyapatite coating on Ti-6Al-4V substrates with considering wear and dissolutions.

    Science.gov (United States)

    Otsuka, Yuichi; Kojima, Daisuke; Mutoh, Yoshiharu

    2016-12-01

    This study aims at developing the prediction model of cyclic delamination lives of plasma-sprayed HAp coating on Ti-6Al-4V substrate by considering wear by interface contacts and dissolution effect by Simulated Body Fluid (SBF). Delamination of HAp coating can lead to loosening of implants stem and final failure in vivo. In the fracture mechanism of interfaces between HAp coating with Ti substrates, only adhesive strength (interracial tensile strength) or fatigue behavior by longitudinal cracking have been observed. Cyclic delamination mechanism by considering various loading modes and corrosion effect has not been revealed yet. The interface delamination rates by cyclic loading were much higher than those by static loading tests. The result clearly demonstrated that the interface demalination behaviors are dominated not by maximum stress, but by stress range. Surface profile measurement and SEM observation also demonstrated damages by interface contact or third body wear at delamination tips of HAp coating only in the cases of compressions. The mechanisms of acceleration on the delaminations are third-body wear or wedge effect by worn particles which increased mean stress level during cyclic loading. Cyclic loading tests under SBF also revealed that cyclic delamination lives were shortened probably due to crevice corrosion at interfaces. Dissolutions at the tips of delaminations were observed by SEM images under tensile loading condition in SBF. Linearly adding the effects of wear and dissolutions into Paris law could successfully predict the delamination lives of HAp coating for various loading ratios in SBF. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  1. Evaluation of Microscopic Deformation Behaviors of Metal Matrix Composite due to Heat Treatment by means of SFC Test and Acoustic Emission

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Moon Phil; Lee, Joon Hyun [Pusan National University, Busan (Korea, Republic of)

    2000-10-15

    Metal matrix composite(MMCs) have been rapidly becoming one of the strongest candidates for structural materials for high temperature application. It is well recognized that MMCs always experience at least one large cool-down from processing temperature before my significant applied service loading. Due to the large difference in thermal expansion coefficient between the fiber and matrix, large thermal residual stresses generally develop in composites. It was reported from many previous studies that the effects of thermal residual stress on mechanical properties and fracture behavior were much more complex and dramatic than conventional engineering materials. Therefore it is crucial to evaluate the effect of heat treatment which changes the characteristic of distribution of thermal residual stress in MMCs. Single fiber composite(SFC) test based on the balance in a micromechanical model is a quite convenient method to evaluate interfacial shear strength(IFSS) and the failure mode of composite. In this study the effect of heat treatment on IFSS and the microscopic failure mechanism of MMC is investigated by combining acoustic emission(AE) technique with SFC test. The characteristic of AE signal, IFSS and microscopic failure mechanism due to heat treatment condition is discussed

  2. Experimental study on slip behavior between shaped steel and concrete in SRC columns under cyclic reversed loading%低周反复荷载下型钢混凝土柱滑移性能试验研究

    Institute of Scientific and Technical Information of China (English)

    李俊华; 薛建阳; 赵鸿铁

    2008-01-01

    通过在型钢翼缘外侧滑移传感器,对轴力和反复水平荷载作用下型钢混凝土柱的粘结滑移性能进行了试验研究.试验中主要考虑了跨比、轴压比、配箍率、混凝土强度的影响.由试验得到了水平荷载-滑移滞回曲线和骨架曲线、滑移沿柱高的分布规律等.试验结果表明,型钢混凝土的荷载-滑移滞回曲线比较丰满,在整个加载过程中没有明显的"捏拢"现象;滑移沿柱高大致呈指数分布,柱根位置的滑移量最大,由柱根向柱顶逐渐递减;当剪跨比小于2时,滑移随剪跨比的增大而减小,当剪跨比大于2以后,滑移又随剪跨比的增大而增大;滑移随着轴压比的增大增大,随着配箍率和混凝土强度的提高而减小;随着荷载循环次数的增加,滑移刚度不断减小,滑移量不断增大,出现明显的粘结退化现象.%Slip distribution behavior of SRC (steel reinforced concrete) columns under constant axial load together with cyclic reversed horizontal load is studied by embedding slip transfers on the flanges of shaped steel. Four test parameters,i. e., shear span ratio, axial compression ratio, stirrup ratio and volumetric ratio and concrete strength are taken into consideration- Hysteretic and skeleton curves of slip against horizontal load as well as slip distribution law along columns are obtained from tests. Test results show that the hysteretic curve of slip against horizontal load is chubbiness and fold phenomenon does not occur in the course of loading. The interior slip between shaped steel and concrete is exponentially distributed along the columns. Maximum slips lie in the bottom of columns, and gradually descend from bottom to top. Slip increases with the increase of axial compression ratio, but decrease with the increase of stirrup ratio or concrete strength.When the shear span ratio is less than 2. 0, slip decreases with the increase of shear span ratio, but when shear span ratio exceeds 2

  3. 铝合金7A04在干湿周浸条件下的腐蚀行为研究%The Corrosion Behavior of Aluminum Alloy 7A04 under Cyclic Wet-Dry Immersion Conditions

    Institute of Scientific and Technical Information of China (English)

    周和荣; 李晓刚; 肖葵; 董超芳

    2009-01-01

    采用扫描电镜、X光电子能谱、失重法和电化学交流阻抗技术研究了铝合金7A04在0.6 mol/L NaCl溶液和0.6 mol/LNaCl+0.02mol/L NaHSO3溶液中干湿周浸后的腐蚀行为和规律,并测试了3种材料力学性能的变化.研究结果表明,随试验时间的延长,铝合金腐蚀产物不断增多,腐蚀失重符合指数规律C=A tn,抗拉强度和延伸率呈下降趋势;表面腐蚀产物形貌呈块状,在0.6 mol/L NaCl溶液中腐蚀产物主要为氢氧化铝和氯化铝,而在0.6 mol/LNaCl+0.02 mol/LNaHSO3溶液中腐蚀产物主要为氢氧化铝、氯化铝和硫酸铝.电化学交流阻抗谱显示铝合金7A04在0.6 mol/L NaCI+0.02 mol/0L NaHSO3溶液中的腐蚀速率远大于在0.6 mol/L NaCl溶液的腐蚀速率,并探讨了其腐蚀机理.%The corrosion behavior of aluminum alloy 7A04 under cyclic wet-dry immersion conditions was investigated in 0.6 mol/L sodium chloride solution and 0.6 mol/L sodium chloride+F0.02 mol/L sodium sulfite solution by Scanning electron microscopy (SEM),energy dispersive X-ray detection (EDS),X-ray photoelectron spectroscopy (XPS),mass loss method,mechanical capability test and electrochemical impedance spectroscopy (EIS).The results showed that the mass loss increases with corrosion time prolonging,and according with the rule as C=Atn,strength and elongation percentage are declining.Surface observation revealed that corrosion product is agglomerated and accidented.The corrosion products are AI(OH)3 and aluminum chloride in 0.6 mol/L sodium chloride solution,and Al(OH)3,aluminum sulfate and chloride in 0.6 mol/L sodium chloride and 0.02 mol/L sodium anlfite solution.The EIS results indicated that corrosion rate in 0.6 mol/L sodium chloride and 0.02 mol/Lsodium sulfite solution is higher than that in 0.6 mol/L sodium chloride solution.The corrosion reaction mechanism was discussed.

  4. 环甲基硅氧烷的环境分布、行为与效应研究进展%The Research Progress of Environmental Distribution, Behavior and Effects of Cyclic Methylsiloxanes

    Institute of Scientific and Technical Information of China (English)

    张松林; 吴丽华

    2016-01-01

    In recent years, the cyclic volatile methyl siloxanes (cVMS) are widely used in the process of production and people’ s daily life because of their excellent performance, meanwhile leading to increasing environmental and human exposure risks and receiving dramatic concerns because of their persistence, potential biological accumula ̄tion and toxicity. At present, researchers have a certain understanding about the occurrence, behavior and effects of cVMS in various environmental media all over the world. Most cVMS were discharged into the atmosphere, and some cVMS were found in water, sediment, soil and organism. Many studies have shown that the highest median of the total cyclic siloxane of indoor air dust was from Greek (1 380 ng•g ̄1 ), and followed by China (362 ng•g ̄1 ). The total siloxane flux per capita for sewage treatment plant in China (10 g•y ̄1 ) was much lower than that of UK (48.3 g•y ̄1 for D4 ̄D6) and the United States (93.5 g•y ̄1for D4 ̄D6). The total cVMS concentration (1.05μg•L ̄1) from a sewage treatment plant with CWSBR in Dalian was generally lower than that of Greece (5.14 μg•L ̄1 ), Spain (9.2 μg•L ̄1), Canada (44μg•L ̄1) and some of the Nordic countries (17μg•L ̄1). In the aspect of the methyl siloxane of sewage sludge from wastewater treatment plant, China (0.1 ̄l μg•g ̄1 dw) was also much lower than some of the Nordic countries (26μg•g ̄1 dw), Greece (20μg•g ̄1 dw) and Canada (64μg•g ̄1 dw). The PEL (pseu ̄do ̄exposure level) median (173 ng•d ̄1 ) of D4 ̄D6 by inhaling and feeding for ordinary residents was much lower than the average median (18.5 μg•d ̄1) by skin exposure in China, and much lower than the exposure level (1.875 mg•d ̄1 ) for adult in the UK and for women (307 mg•d ̄1 ) exposed to the total siloxane in the United States. Gener ̄ally, the behavior and the effect of cVMS discharged into environment depend on the physical and chemical prop

  5. Work-focused cognitive behavioral intervention for psychological complaints in patients on sick leave due to work-related stress: Results from a randomized controlled trial.

    Science.gov (United States)

    Dalgaard, Vita Ligaya; Andersen, Lars Peter Sønderbo; Andersen, Johan Hviid; Willert, Morten Vejs; Carstensen, Ole; Glasscock, David John

    2017-08-22

    Work-related stress is a global problem with negative implications for individuals and society. The purpose of the current study was to evaluate a stress management intervention for patients on sick leave due to work-related stress complaints using a three-armed randomized controlled design. Participants were patients referred from three municipalities to the regional Department of Occupational Medicine. Inclusion criteria were: 1) sick leave due to work-related stress complaints, 2) a diagnosis of adjustment disorder or reactions to severe stress (ICD 10 code: F43,2 - F 43,9 not PTSD) or mild depressive episode (F 32.0). Through a double randomization procedure patients (n = 163) were randomized to either an intervention group (n = 58), a 'control group A' receiving a clinical examination (n = 56), or 'control group B' (n = 49) receiving no offers at the department. The intervention comprised six sessions of individual cognitive behavioral therapy and the offer of a small workplace intervention. Questionnaire data were analyzed with multivariate repeated measurements analysis. Primary outcomes assessed were perceived stress and general mental health. Secondary outcomes were sleep quality and cognitive failures. Follow-up was at four and 10 months after baseline. Complaints were significantly reduced in all groups over time. No group effects were observed between the intervention group and control group A that was clinically assessed. Significant group effects were found for perceived stress and memory when comparing the intervention group to group B, but most likely not due to an intervention effect. Psychological complaints improved substantially over time in all groups, but there was no significant treatment effect on any outcomes when the intervention group was compared to control group A that received a clinical assessment. ISRCTN ISRCTN91404229. Registered 03 August 2012 (retrospectively registered).

  6. Behavior of concentrically loaded CFT braces connections

    Directory of Open Access Journals (Sweden)

    Maha M. Hassan

    2014-03-01

    Full Text Available Concrete filled tubes (CFTs composite columns have many economical and esthetic advantages, but the behavior of their connections is complicated. Through this study, it is aimed to investigate the performance and behavior of different connection configurations between concrete filled steel tube columns and bracing diagonals through an experimental program. The study included 12 connection subassemblies consisting of a fixed length steel tube and gusset plate connected to the tube end with different details tested under half cyclic loading. A notable effect was observed on the behavior of the connections due to its detailing changes with respect to capacity, failure mode, ductility, and stress distribution.

  7. Behavior of concentrically loaded CFT braces connections.

    Science.gov (United States)

    Hassan, Maha M; Ramadan, Hazem M; Abdel-Mooty, Mohammed N; Mourad, Sherif A

    2014-03-01

    Concrete filled tubes (CFTs) composite columns have many economical and esthetic advantages, but the behavior of their connections is complicated. Through this study, it is aimed to investigate the performance and behavior of different connection configurations between concrete filled steel tube columns and bracing diagonals through an experimental program. The study included 12 connection subassemblies consisting of a fixed length steel tube and gusset plate connected to the tube end with different details tested under half cyclic loading. A notable effect was observed on the behavior of the connections due to its detailing changes with respect to capacity, failure mode, ductility, and stress distribution.

  8. Manual for Cyclic Triaxial Test

    DEFF Research Database (Denmark)

    Shajarati, Amir; Sørensen, Kris Wessel; Nielsen, Søren Kjær

    /dynamic triaxial cell is overall constructed in the same way as the static triaxial cell at Aalborg University, but with the ability to apply any kind of load sequence to the test sample. When conducting cyclic triaxial tests, it is recommended that the manual is followed very tediously since there are many steps...... and if they are done improperly or in the wrong order there is a risk of destroying the test sample or obtaining invalid results.......This manual describes the different steps that is included in the procedure for conducting a cyclic triaxial test at the geotechnical Laboratory at Aalborg University. Furthermore it contains a chapter concerning some of the background theory for the static triaxial tests. The cyclic...

  9. Design of a cyclic multiverse

    Energy Technology Data Exchange (ETDEWEB)

    Piao Yunsong, E-mail: yspiao@gucas.ac.c [College of Physical Sciences, Graduate School of Chinese Academy of Sciences, Beijing 100049 (China)

    2010-08-09

    Recently, it has been noticed that the amplification of the amplitude of curvature perturbation cycle by cycle can lead to a cyclic multiverse scenario, in which the number of universes increases cycle by cycle. However, this amplification will also inevitably induce either the ultimate end of corresponding cycle, or the resulting spectrum of perturbations inside corresponding universe is not scale invariant, which baffles the existence of observable universes. In this Letter, we propose a design of a cyclic multiverse, in which the observable universe can emerges naturally. The significance of a long period of dark energy before the turnaround of each cycle for this implementing is shown.

  10. Recursive processing of cyclic graphs.

    Science.gov (United States)

    Bianchini, Monica; Gori, Marco; Sarti, Lorenzo; Scarselli, Franco

    2006-01-01

    Recursive neural networks are a powerful tool for processing structured data. According to the recursive learning paradigm, the input information consists of directed positional acyclic graphs (DPAGs). In fact, recursive networks are fed following the partial order defined by the links of the graph. Unfortunately, the hypothesis of processing DPAGs is sometimes too restrictive, being the nature of some real-world problems intrinsically cyclic. In this paper, a methodology is proposed, which allows us to process any cyclic directed graph. Therefore, the computational power of recursive networks is definitely established, also clarifying the underlying limitations of the model.

  11. Small-Scale Testing of Cyclic Laterally Loaded Monopiles in Dense Saturated Sand

    DEFF Research Database (Denmark)

    Nicolai, Giulio; Ibsen, Lars Bo

    2014-01-01

    Monopiles are currently the most common foundations for offshore wind turbines, which are subjected to millions of cyclic loads that are still not well interpreted in the design guidelines. The accumulated rotation of the turbine and the change of foundation stiffness due to the long-term cyclic ...

  12. DEFORMATION CHARACTERISTICS OF CRUSHED-STONE LAYER UNDER CYCLIC IMPACT LOADING FROM MICRO-MECHANICAL VIEW

    Science.gov (United States)

    Kono, Akiko; Matsushima, Takashi

    'Hanging sleepers', which have gaps between sleepers and ballast layer are often found in the neighborhood of rail joints or rugged surface rails. This suggests that differential settlement of the ballast layer is due to impact loading generated by the contact between running wheel and rugged surface rail. Then cyclic loading tests were performed on crushed-stone layer with two loading patterns, the one is a cyclic impact loading and the other one is cyclic 'standard' loading controlled at 1/10 loading velocity of the impact loading. It was shown that the crashed-stone layer deforms with volumetric expansion during every off-loading processes under the cyclic impact loading. This phenomena prevents crushed stone layer from forming stable grain columns, then the residual settlement under the cyclic impact loading is larger than that under the cyclic 'standard' loading. A simple mass-spring model simulates that two masses move in the opposite direction with increased frequency of harmonic excitation.

  13. Behaviorism

    National Research Council Canada - National Science Library

    Moore, J

    2011-01-01

    .... Watson proposed an alternative: classical S-R behaviorism. According to Watson, behavior was a subject matter in its own right, to be studied by the observational methods common to all sciences...

  14. Determination of behavioral reactions of a child of 3-6 ages group to be hospitalized due to an acute illnessDetermination of behavioral reactions of a child of 3-6 ages group to be hospitalized due to an acute illness

    Directory of Open Access Journals (Sweden)

    Nesrin Şen Celasin

    2010-02-01

    Full Text Available The study is executed with mothers of children aged 3-6 (n=170 whose children were hospitalized for the first time between the dates of 15.07.2003 and 15.06.2006, who were reachable by phone and accepted to participate in the study aiming determination of behavioral reactions of a child of 3-6 ages group to be hospitalized due to an acute illness.In this study, for data gathering "Personal Information Form" including 15 questions and "Inquiry Form of Behavior Changes of 3-6 Ages Group Children After Being Hospitalized" with 30 questions were used. Date gathering forms were carried out as pre-test by using face-to-face interview method with mothers of 3-6 aged children who were hospitalized for the first time and were in first 12 hours of hospitalization. "Inquiry Form of Behavior Changes of 3-6 Ages Group Children After Being Hospitalized" was re-carried out with mothers by phone 1 month after children being discharged from hospital.In analyzing of datas statistical programme of SPSS 13.0 for Windows was used. In statistical evaluation; number-percent dispersion, Wilcoxon Sing Rank test and Paired Sample-t test were used.According to the results obtained from the study, 57.6% of children are male with age average of 4,46±1,18 and 52.3% of them were hospitalized due to Gastroentestinal System Illnesses. A significant difference was determined between average points of behavior changes of 3-6 ages group children hospitalized due to an acute illness before hospitalized (10,735±4,882 and after being discharged from hospital (15,0476±4,306. In the study, it is observed that there are some behavioral changes in children after being hospitalized such as being cranky before going to bed and during eating, disquiet, bed-wetting, seperation anxiety, excessive attachment to a parent, to need help even for the things he/she could accomplish, to have fear from new environments, people or objects, bad temper attacks, fear of doctor/nurse and hospital, fear

  15. Cyclic Testing of Steel Chevron Braces with Vertically Slotted Beam Connection

    Directory of Open Access Journals (Sweden)

    Rozlyn K. Bubela

    2010-07-01

    Full Text Available Experimental tests were performed to study the seismic behavior and performance of modified steel chevron braced frame systems, which incorporate a vertical slotted connection (VSC detail between the top of the braces and the floor beam above. The VSC detail is intended to prevent vertical load transfer to the beam and limit brace forces to the compressive resistance of the members. Full-scale quasi-static cyclic tests were performed on two specimens with hollow tube braces, with one specimen having the braces filled with concrete. Both frames exhibited stable, predictable behavior under cyclic loading. The VSC detail provided free vertical movement of the brace assembly during both tests. However, its flexibility created a moderate reduction in the overall lateral stiffness of the frame. The concrete-filled tube specimen sustained higher peak loads, demonstrated greater residual strength and dissipated more energy than the hollow tube specimen due to the partial inhibition of local buckling by the concrete core. It was found that the VSC chevron braced frame system is a suitable concept for use in buildings in high-risk seismic zones.

  16. Oscillatory behavior of the tunnel magnetoresistance due to thickness variations in Ta|CoFe|MgO magnetic tunnel junctions: A first-principles study

    Science.gov (United States)

    Sankaran, K.; Swerts, J.; Couet, S.; Stokbro, K.; Pourtois, G.

    2016-09-01

    To investigate the impact of both the CoFe ferromagnetic layer thickness and the capping paramagnetic layer on the tunnel magnetoresistance (TMR), we performed first-principles simulations on epitaxial magnetic tunnel junctions contacted with either CoFe or Ta paramagnetic capping layers. We observed a strong oscillation of the TMR amplitude with respect to the thickness of the ferromagnetic layer. The TMR is found to be amplified whenever the MgO spin tunnel barrier is thickened. Quantization of the electronic structure of the ferromagnetic layers is found to be at the origin of this oscillatory behavior. Metals such as Ta contacting the magnetic layer are found to enhance the amplitude of the oscillations due to the occurrence of an interface dipole. The latter drives the band alignment and tunes the nature of the spin channels that are active during the tunneling process. Subsequently, the regular transmission spin channels are modulated in the magnetic tunnel junction stack and other complex ones are being activated.

  17. Color visualization of cyclic magnitudes

    Science.gov (United States)

    Restrepo, Alfredo; Estupiñán, Viviana

    2014-02-01

    We exploit the perceptual, circular ordering of the hues in a technique for the visualization of cyclic variables. The hue is thus meaningfully used for the indication of variables such as the azimuth and the units of the measurement of time. The cyclic (or circular) variables may be both of the continuous type or the discrete type; among the first there is azimuth and among the last you find the musical notes and the days of the week. A correspondence between the values of a cyclic variable and the chromatic hues, where the natural circular ordering of the variable is respected, is called a color code for the variable. We base such a choice of hues on an assignment of of the unique hues red, yellow, green and blue, or one of the 8 even permutations of this ordered list, to 4 cardinal values of the cyclic variable, suitably ordered; color codes based on only 3 cardinal points are also possible. Color codes, being intuitive, are easy to remember. A possible low accuracy when reading instruments that use this technique is compensated by fast, ludic and intuitive readings; also, the use of a referential frame makes readings precise. An achromatic version of the technique, that can be used by dichromatic people, is proposed.

  18. Cyclic Codes of Length 2

    Indian Academy of Sciences (India)

    Manju Pruthi

    2001-11-01

    In this paper explicit expressions of + 1 idempotents in the ring $R = F_q[X]/\\langle X^{2^m}-1\\rangle$ are given. Cyclic codes of length 2 over the finite field , of odd characteristic, are defined in terms of their generator polynomials. The exact minimum distance and the dimension of the codes are obtained.

  19. Universal Responses of Cyclic-Oxidation Models Studied

    Science.gov (United States)

    Smialek, James L.

    2003-01-01

    Oxidation is an important degradation process for materials operating in the high-temperature air or oxygen environments typical of jet turbine or rocket engines. Reaction of the combustion gases with the component material forms surface layer scales during these oxidative exposures. Typically, the instantaneous rate of reaction is inversely proportional to the existing scale thickness, giving rise to parabolic kinetics. However, more realistic applications entail periodic startup and shutdown. Some scale spallation may occur upon cooling, resulting in loss of the protective diffusion barrier provided by a fully intact scale. Upon reheating, the component will experience accelerated oxidation due to this spallation. Cyclic-oxidation testing has, therefore, been a mainstay of characterization and performance ranking for high-temperature materials. Models simulate this process by calculating how a scale spalls upon cooling and regrows upon heating (refs. 1 to 3). Recently released NASA software (COSP for Windows) allows researchers to specify a uniform layer or discrete segments of spallation (ref. 4). Families of model curves exhibit consistent regularity and trends with input parameters, and characteristic features have been empirically described in terms of these parameters. Although much insight has been gained from experimental and model curves, no equation has been derived that can describe this behavior explicitly as functions of the key oxidation parameters.

  20. THE STRENGTH OF REINFORCED CONCRETE BEAM ELEMENTS UNDER CYCLIC ALTERNATING LOADING AND LOW CYCLE LOAD OF CONSTANT SIGN

    Directory of Open Access Journals (Sweden)

    Semina Yuliya Anatol'evna

    2015-09-01

    Full Text Available The behavior of reinforced concrete elements under some types of cyclic loads is described in the paper. The main aim of the investigations is research of the stress-strain state and strength of the inclined sections of reinforced concrete beam elements in conditions of systemic impact of constructive factors and the factor of external influence. To spotlight the problem of cyclic loadings three series of tests were conducted by the author. Firstly, the analysis of the tests showed that especially cyclic alternating loading reduces the bearing capacity of reinforced concrete beams and their crack resistance by 20 % due to the fatigue of concrete and reinforcement. Thus the change of load sign creates serious changes of stress-strain state of reinforced concrete beam elements. Low cycle loads of constant sign effect the behavior of the constructions not so adversely. Secondly, based on the experimental data mathematical models of elements’ strength were obtained. These models allow evaluating the impact of each factor on the output parameter not only separately, but also in interaction with each other. Furthermore, the material spotlighted by the author describes stress-strain state of the investigated elements, cracking mechanism, changes of deflection values, the influence of mode cyclic loading during the tests. Since the data on the subject are useful and important to building practice, the ultimate aim of the tests will be working out for improvement of nonlinear calculation models of span reinforced concrete constructions taking into account the impact of these loads, and also there will be the development of engineering calculation techniques of their strength, crack resistance and deformability.

  1. Powers of Convex-Cyclic Operators

    Directory of Open Access Journals (Sweden)

    Fernando León-Saavedra

    2014-01-01

    Full Text Available A bounded operator T on a Banach space X is convex cyclic if there exists a vector x such that the convex hull generated by the orbit Tnxn≥0 is dense in X. In this note we study some questions concerned with convex-cyclic operators. We provide an example of a convex-cyclic operator T such that the power Tn fails to be convex cyclic. Using this result we solve three questions posed by Rezaei (2013.

  2. CYCLIC CODES OVER FORMAL POWER SERIES RINGS

    Institute of Scientific and Technical Information of China (English)

    Dougherty Steven T.; Liu Hongwei

    2011-01-01

    In this article, cyclic codes and negacyclic codes over formal power series rings are studied. The structure of cyclic codes over this class of rings is given, and the relationship between these codes and cyclic codes over finite chain rings is obtained. Using an isomorphism between cyclic and negacyclic codes over formal power series rings, the structure of negacyclic codes over the formal power series rings is obtained.

  3. 40 CFR 721.2120 - Cyclic amide.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Cyclic amide. 721.2120 Section 721... Cyclic amide. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as a cyclic amide (PMN P-92-131) is subject to reporting under this section for...

  4. The cyclic theory of Hopf algebroids

    NARCIS (Netherlands)

    Kowalzig, N.; Posthuma, H.

    2011-01-01

    We give a systematic description of the cyclic cohomology theory of Hopf alge\\-broids in terms of its associated category of modules. Then we introduce a dual cyclic homology theory by applying cyclic duality to the underlying cocyclic object. We derive general structure theorems for these theories

  5. The Cyclic Graph of a Finite Group

    Directory of Open Access Journals (Sweden)

    Xuan Long Ma

    2013-01-01

    and characterize certain finite groups whose cyclic graphs have some properties. Then, we present some properties of the cyclic graphs of the dihedral groups D2n and the generalized quaternion groups Q4n for some n. Finally, we present some parameters about the cyclic graphs of finite noncyclic groups of order up to 14.

  6. Diselenide-Labeled Cyclic Polystyrene with Multiple Responses: Facile Synthesis, Tunable Size, and Topology.

    Science.gov (United States)

    Cai, Zhaoxiong; Lu, Weihong; Gao, Feng; Pan, Xiangqiang; Zhu, Jian; Zhang, Zhengbiao; Zhu, Xiulin

    2016-05-01

    Diselenide-containing polymers have attracted more and more attention due to their redox sensitivity and bioapplication. In this work, a bifunctional diselenocarbonate is prepared and used to mediate the reversible addition-fragmentation chain transfer (RAFT) polymerization, producing α,ω-selenocarbonate-labeled telechelic polystyrene. Based on effective aminolysis of the terminal selenocarbonates and the followed spontaneous oxidation coupling reaction of diselenols, monoblock cyclic polystyrene linked by one diselenide bond and multiblock cyclic copolymer linked by several diselenide bonds are prepared by manipulating the concentration of α,ω-telechelic polystyrene in solution. The progress of aminolysis and the subsequent spontaneous oxidation of selenols to diselenides are monitored by UV-vis, gel permeation chromatography (GPC), and NMR characterizations, confirming the cyclic topologies of the resultant polymers (monocyclic or multiblock cyclic polymer). The monoblock cyclic or multiblock polymers show redox sensitivity, which can be converted to linear polymer by reducing or oxidizing agent. Moreover, the obtained monoblock cyclic polymer or multiblock cyclic copolymer can be transformed to each other under UV irradiation by adjusting the concentration of the cyclic polystyrene. For the first time, this work provides an alternative and promising approach to realize the topological transformation of polymers by installing multiresponsive diselenide moities into the backbone of cyclic polymer.

  7. Behaviorism

    Science.gov (United States)

    Moore, J.

    2011-01-01

    Early forms of psychology assumed that mental life was the appropriate subject matter for psychology, and introspection was an appropriate method to engage that subject matter. In 1913, John B. Watson proposed an alternative: classical S-R behaviorism. According to Watson, behavior was a subject matter in its own right, to be studied by the…

  8. Behaviorism

    Science.gov (United States)

    Moore, J.

    2011-01-01

    Early forms of psychology assumed that mental life was the appropriate subject matter for psychology, and introspection was an appropriate method to engage that subject matter. In 1913, John B. Watson proposed an alternative: classical S-R behaviorism. According to Watson, behavior was a subject matter in its own right, to be studied by the…

  9. Characterization of cyclical phases in the manufacturing industry in Spain

    Directory of Open Access Journals (Sweden)

    Mercè Sala

    2014-09-01

    Full Text Available 120 Purpose: The purpose of this paper is to characterize the cyclical phases of the manufacturing industry in Spain and detect which industries have more influence on the Spanish business cycle. We assume that economic growth is a priority; we are going to determine which industries have a more/less appropriate cyclical behavior according this priority. We analyze if the industries with better cyclical behavior are the ones that achieve greater co-movement with the business cycle of the Spanish economy, as this means they have a positive influence on economic activity. Design/methodology/approach: We examine the disaggregated quarterly IPI data of 16 manufacturing industries. Our methodology follows three steps. Firstly, we define cycle turning points; we follow the Harding and Pagan (2002 methodology. Secondly, we characterize the cyclical phases of the manufacturing industries in terms of duration, amplitude, deepness and steepness. We also determine the degree of inter-industrial cyclical synchronization and between industries in the cycle of the Spanish economy. This analysis is performed in two ways. On the one hand, we use the concordance index and the correlation coefficient. On the other hand, we work with indicators based on a consistency table. In the Third step, we apply a multi-objective methodology, specifically the compromise programming, to determine which industries have a more/less appropriate cyclical behavior according to the growth priority. Findings and Originality/value: The business cycle of the Spanish economy is positively influenced by high- and medium-tech industries, which have demonstrated their competitive capacity in international markets, and by medium- low-tech industries, with major strengths in R&D, and in survival and consolidation strategies. These results enable manufacturing industries to exert a positive effect on the business cycle that is weakened because many of them show a high correlation between

  10. Cyclical Fluctuations in Workplace Accidents

    OpenAIRE

    Boone, J.; J. C. VAN OURS

    2002-01-01

    This Paper presents a theory and an empirical investigation on cyclical fluctuations in workplace accidents. The theory is based on the idea that reporting an accident dents the reputation of a worker and raises the probability that he is fired. Therefore a country with a high or an increasing unemployment rate has a low (reported) workplace accident rate. The empirical investigation concerns workplace accidents in OECD countries. The analysis confirms that workplace accident rates are invers...

  11. Theory of chromatography of partially cyclic polymers: Tadpole-type and manacle-type macromolecules.

    Science.gov (United States)

    Vakhrushev, Andrey V; Gorbunov, Alexei A

    2016-02-12

    A theory of chromatography is developed for partially cyclic polymers of tadpole- and manacle-shaped topological structures. We present exact equations for the distribution coefficient K at different adsorption interactions; simpler approximate formulae are also derived, relevant to the conditions of size-exclusion, adsorption, and critical chromatography. Theoretical chromatograms of heterogeneous partially cyclic polymers are simulated, and conditions for good separation by topology are predicted. According to the theory, an effective SEC-radius of tadpoles and manacles is mostly determined by the molar mass M, and by the linear-cyclic composition. In the interactive chromatography, the effect of molecular topology on the retention becomes significant. At the critical interaction point, partial dependences K(Mlin) and K(Mring) are qualitatively different: while being almost independent of Mlin, K increases with Mring. This behavior could be realized in critical chromatography-for separation of partially cyclic polymers by the number and molar mass of cyclic elements.

  12. Acute changes in hamstrings musculo-articular dissipative properties induced by cyclic and static stretching.

    Science.gov (United States)

    Nordez, A; McNair, P; Casari, P; Cornu, C

    2008-05-01

    This study was designed to measure changes in musculo-articular dissipative properties related to viscosity that were induced by passive cyclic and static stretching. Musculo-articular dissipative properties were assessed by calculating a dissipation coefficient using potential elastic energies stored and restituted during cyclic stretching. Eight subjects performed five passive knee extensions/flexions cycles on a Biodex dynamometer at 5 degrees . s (-1) to 80 % of their maximal range of motion before and after a static stretching protocol. Electromyographic activity from the hamstring muscles was monitored and remained constant during cyclic stretching and after static stretching (p > 0.05). The dissipation coefficient decreased during cyclic stretching (- 28.8 +/- 6.0 %, p musculo-articular dissipative properties were primarily affected by a single cycle of motion, and were not influenced by static stretching procedures. The decrease in dissipation coefficient following cyclic motion indicates that the musculo-articular system displays thixotropic behavior.

  13. Supramolecular nesting of cyclic polymers.

    Science.gov (United States)

    Kondratuk, Dmitry V; Perdigão, Luís M A; Esmail, Ayad M S; O'Shea, James N; Beton, Peter H; Anderson, Harry L

    2015-04-01

    Advances in template-directed synthesis make it possible to create artificial molecules with protein-like dimensions, directly from simple components. These synthetic macromolecules have a proclivity for self-organization that is reminiscent of biopolymers. Here, we report the synthesis of monodisperse cyclic porphyrin polymers, with diameters of up to 21 nm (750 C–C bonds). The ratio of the intrinsic viscosities for cyclic and linear topologies is 0.72, indicating that these polymers behave as almost ideal flexible chains in solution. When deposited on gold surfaces, the cyclic polymers display a new mode of two-dimensional supramolecular organization, combining encapsulation and nesting; one nanoring adopts a near-circular conformation, thus allowing a second nanoring to be captured within its perimeter, in a tightly folded conformation. Scanning tunnelling microscopy reveals that nesting occurs in combination with stacking when nanorings are deposited under vacuum, whereas when they are deposited directly from solution under ambient conditions there is stacking or nesting, but not a combination of both.

  14. Development of plastic deformations in 12Kh18N10T steel under cyclic symmetrical bending of specimens of various length

    Energy Technology Data Exchange (ETDEWEB)

    Pisarenko, G.S.; Leonets, V.A.; Bega, N.D. (AN Ukrainskoj SSR, Kiev. Inst. Problem Prochnosti)

    1983-08-01

    Effect of specimen length on intensity of plastic deformation development and cyclic strength is studied for annealed 12Kh18N10T steel under cyclic symmetrical bending. The intensity of microplastic deformations and cyclic strength of annealed 12Kh18N10T steel in the considered case is due to self-heating.

  15. Controls on Precambrian sea level change and sedimentary cyclicity

    Science.gov (United States)

    Eriksson, P. G.; Catuneanu, O.; Nelson, D. R.; Popa, M.

    2005-04-01

    Although uniformitarianism applies in a general sense to the controls on relative and global sea level change, some influences thereon were more prominent in the Precambrian. Short-term base level change due to waves and tides may have been enhanced due to possibly more uniform circulation systems on wide, low gradient Precambrian shelves. The lack of evidence for global glacial events in the Precambrian record implies that intraplate stresses and cyclic changes to Earth's geoid were more likely explanations for third-order sea level change than glacio-eustasy. Higher heat flow in the earlier Precambrian may have led to more rapid tectonic plate formation, transport and destruction, along with an increased role for hot spots, aseismic ridges and mantle plumes (superplumes), all of which may have influenced cyclic sedimentation within the ocean basins. A weak cyclicity in the occurrence of plume events has an approximate duration comparable to that of first-order (supercontinental cycle) sea level change. Second-order cyclicity in the Precambrian largely reflects the influences of thermal epeirogeny, changes to mid-ocean ridge volume as well as to ridge growth and decay rates, and cratonic marginal downwarping concomitant with either sediment loading or extensional tectonism. Third-order cycles of sea level change in the Precambrian also reflected cyclic loading/unloading within flexural foreland basin settings, and filling/deflation of magma chambers associated with island arc evolution. The relatively limited number of studies of Precambrian sequence stratigraphy allows some preliminary conclusions to be drawn on duration of the first three orders of cyclicity. Archaean greenstone basins appear to have had first- and second-order cycle durations analogous to Phanerozoic equivalents, supporting steady state tectonics throughout Earth history. In direct contrast, however, preserved basin-fills from Neoarchaean-Palaeoproterozoic cratonic terranes have first- and

  16. Cyclic modular beta-sheets.

    Science.gov (United States)

    Woods, R Jeremy; Brower, Justin O; Castellanos, Elena; Hashemzadeh, Mehrnoosh; Khakshoor, Omid; Russu, Wade A; Nowick, James S

    2007-03-07

    The development of peptide beta-hairpins is problematic, because folding depends on the amino acid sequence and changes to the sequence can significantly decrease folding. Robust beta-hairpins that can tolerate such changes are attractive tools for studying interactions involving protein beta-sheets and developing inhibitors of these interactions. This paper introduces a new class of peptide models of protein beta-sheets that addresses the problem of separating folding from the sequence. These model beta-sheets are macrocyclic peptides that fold in water to present a pentapeptide beta-strand along one edge; the other edge contains the tripeptide beta-strand mimic Hao [JACS 2000, 122, 7654] and two additional amino acids. The pentapeptide and Hao-containing peptide strands are connected by two delta-linked ornithine (deltaOrn) turns [JACS 2003, 125, 876]. Each deltaOrn turn contains a free alpha-amino group that permits the linking of individual modules to form divalent beta-sheets. These "cyclic modular beta-sheets" are synthesized by standard solid-phase peptide synthesis of a linear precursor followed by solution-phase cyclization. Eight cyclic modular beta-sheets 1a-1h containing sequences based on beta-amyloid and macrophage inflammatory protein 2 were synthesized and characterized by 1H NMR. Linked cyclic modular beta-sheet 2, which contains two modules of 1b, was also synthesized and characterized. 1H NMR studies show downfield alpha-proton chemical shifts, deltaOrn delta-proton magnetic anisotropy, and NOE cross-peaks that establish all compounds but 1c and 1g to be moderately or well folded into a conformation that resembles a beta-sheet. Pulsed-field gradient NMR diffusion experiments show little or no self-association at low (

  17. Corrosive electrochemistry of jamesonite by cyclic voltammetry

    Institute of Scientific and Technical Information of China (English)

    余润兰; 胡岳华; 邱冠周; 覃文庆

    2004-01-01

    The corrosive electrochemistry of jamesonite was studied by cyclic voltammetry. Every peak in voltammograms was identified through thermodynamic calculation. The results show an irreversible electrode process by the strong adsorption of oxidation elemental sulfur on jamesonite. A deficient-metal and sulfur-rich compound is formed under the potential of 80 mV at pH 6.86. The passive action by elemental sulfur occurs from 80 to 470 mV and S2O23- , SO24- are produced at potential over 470 mV. The anodic peak producing SO24- is inhibited due to the deposition of PbSO4 at higher potential in Na2SO4 solution. The corrosive action of jamesonite becomes strong and the redox characterization similar to PbS, FeS and Sb2 S3 appears at pH 9.18.

  18. New Cyclic Voltammetry Method for Examining Phase Transitions: Simulated Results

    OpenAIRE

    2006-01-01

    We propose a new experimental technique for cyclic voltammetry, based on the first-order reversal curve (FORC) method for analysis of systems undergoing hysteresis. The advantages of this electrochemical FORC (EC-FORC) technique are demonstrated by applying it to dynamical models of electrochemical adsorption. The method can not only differentiate between discontinuous and continuous phase transitions, but can also quite accurately recover equilibrium behavior from dynamic analysis of systems...

  19. Sectoral Shifts and Cyclical Fluctuations Sectoral Shifts and Cyclical Fluctuations

    Directory of Open Access Journals (Sweden)

    Richard Rogerson

    1991-03-01

    Full Text Available Sectoral Shifts and Cyclical Fluctuations This paper studies a two sector real business cycle model in which the sectors experience different trend rates of growth and labor mobility is costly. Predictions are derived concerning the correlation between sectoral reallocation of workers and the cycle. This correlation may be positive or negative depending upon whether the growing sector displays larger or smaller fluctuations than the shrinking sector. The post- World War II period has witnessed two major patterns of sectoral change in industrialized countries: movement out of agriculture and movement out of the industrial sector. The model's basic prediction is shown to be consistent with the observed pattern of reallocation.

  20. A cyclic time-dependent Markov process to model daily patterns in wind turbine power production

    CERN Document Server

    Scholz, Teresa; Estanqueiro, Ana

    2013-01-01

    Wind energy is becoming a top contributor to the renewable energy mix, which raises potential reliability issues for the grid due to the fluctuating nature of its source. To achieve adequate reserve commitment and to promote market participation, it is necessary to provide models that can capture daily patterns in wind power production. This paper presents a cyclic inhomogeneous Markov process, which is based on a three-dimensional state-space (wind power, speed and direction). Each time-dependent transition probability is expressed as a Bernstein polynomial. The model parameters are estimated by solving a constrained optimization problem: The objective function combines two maximum likelihood estimators, one to ensure that the Markov process long-term behavior reproduces the data accurately and another to capture daily fluctuations. A convex formulation for the overall optimization problem is presented and its applicability demonstrated through the analysis of a case-study. The proposed model is capable of r...

  1. Comportement des fondations et des ancrages de structures marines sous l'effet de sollicitations cycliques Behavior of Foundations and Anchors for Marine Structures under the Effect of Cyclic Stresses

    Directory of Open Access Journals (Sweden)

    Le Tirant P.

    2006-11-01

    Full Text Available L'exploration et l'exploitation des hydrocarbures en haute mer conduisent à la mise en place d'ouvrages fixes ou flottants de dimensions de plus en plus colos sales, par des profondeurs d'eau sans cesse croissantes, atteignant actuellement 200 à 300 mètres en production, un millier de mètres en exploration. Les fondations des ouvrages pétroliers de production comprennent essentiel-lement- les pieux ou groupes de pieux, battus ou forés; - les fondations superficielles à embase poids. Le comportement des fondations ou ancrages de structures sous l'action des sollicitations cycliques est étudié, en fonction de la nature des terrains, à partir - de mesures et d'observations sur des structures réelles; d'expérimentations sur des modèles en semi-grandeur ou de simulations sur modèles réduits. Les exemples donnés situent la diversité des problèmes rencontrés pour l'instal-lation des ouvrages en haute mer et! l'ampleur des travaux nécessaires pour décrire plus correctement les phénomènes d'intéraction sols-structures mannes sous l'effet des chargements cycliques et transitoires et, par suite, mieux optimiser le dimensionnement des fondations et des ancrages. Exploration and production of hydrocarbons in the high seas lead ta the installation of fixed or floating structures having more and more colossal sizes at constantly increasing water depths which now attain 200 ta 300 meters for production and 1000 meters for exploration. The foundations of ail production structures mainly consist of - pilings or groups of pilings, either driven or drilled; superficial gravity foundations the behovior of foundations or anchors for such structures under the effect of cyclic stresses is examined as a function of the nature of formations, on the basis of - measurements and observations on actual structures, experiments with semi-full-sized models or by simulations with scale models. The examples given illustrate the diversity of the problems

  2. Experimental Testing of Monopiles in Sand Subjected to One-Way Long-Term Cyclic Lateral Loading

    DEFF Research Database (Denmark)

    Roesen, Hanne Ravn; Ibsen, Lars Bo; Andersen, Lars Vabbersgaard

    2013-01-01

    In the offshore wind turbine industry the most widely used foundation type is the monopile. Due to the wave and wind forces the monopile is subjected to a strong cyclic loading with varying amplitude, maximum loading level, and varying loading period. In this paper the soil–pile interaction of a ...... tests conducted post cyclic loading indicate that the static ultimate capacity increases with the magnitude of cyclic loading....

  3. The effects of Cr, Co, Al, Mo and Ta on the cyclic oxidation behavior of a prototype cast Ni-base superalloy based on a 2(5) composite statistically designed experiment

    Science.gov (United States)

    Barrett, C. A.

    1984-01-01

    A series of cast Ni-base superalloys were systematically varied at selected levels of Co, Cr, Mo, Ta, and Al. The elemental levels varied were Mo, 0 to 4 percent; Cr, 6 to 18 percent; Co, 0 to 20 percent, Ta, 0 to 8 percent; and Al, 3.25 to 6.25 percent. The cyclic oxidation resistance was determined from specific weight change data as a function of time for 1 hr cycles in static air at 1100 C. The significant terms in decreasing order of their importance were Al, Ta, Cr2, Al-Cr, Cr-Co, Co2, Al-Mo, Cr-Mo, Al-Al, and Mo-Ta. The Al term alone accounted for close to 82 percent of the explained variability. The estimating equation showed that the Al level was the most important and should be at its 6.25 wt % maximum value. The Mo and Ta levels should also be at their maximum 4 and 8 wt % respectively. The cobalt composition should be as low as possible, i.e., 0 wt%. The Cr level optimum varies depending on the other 4 levels. The X-ray diffaction results indicate the most protective scales are alumina/aluminate spinel stabilizized with a tri-rutile oxide high in Ta and Mo.

  4. Cyclic voltammetry of supported BLMs

    Science.gov (United States)

    Murgasova, Renata; Sabo, Jan; Ottova, Angelica L.; Tien, H. T.

    1996-06-01

    The transfer of an electron across a bilayer lipid membrane (BLM) is one of the BLMs most exciting processes. A number of well known electron mediators have been investigated using the method of cyclic voltammetry on a Teflon coated platinum wire, the tip of which has been modified by a self-assembled bilayer lipid membrane (s-BLM). The electrical capacitance of the s-BLM system was measured as a function of frequency. The results are discussed in terms of electron transfer and redox reactions.

  5. 一种适用于饱和黏土循环动力分析边界面塑性模型的隐式积分算法%An implicit integration algorithm in the bounding-surface plasticity model for cyclic behaviors of saturated clay

    Institute of Scientific and Technical Information of China (English)

    刘艳秋; 胡存; 刘海笑

    2013-01-01

    A fully implicit integration scheme in the bounding-surface plasticity model for cyclic behaviors of saturated clay is presented by modifying the conventional implicit return mapping algorithm. Within the critical state framework, based on the concept of shrinking the elastic region to a point, combining isotropic with kinematic hardening rule and a rotated bounding surface, and introducing a damage parameter representing the remolding of the soil fabric, the model can reflect the initial anisotropy, the cyclic stiffness degradation and strength softening of saturated clay under cyclic loading. Firstly, the numerical simulations of the undrained triaxial tests both for isotropic ( K01.0 ) and anisotropic ( K00.67 ) consolidated kaolin clay are carried out with variable strain increments. By comparing with the test data, the rationality, robustness and the accuracy of the new fully implicit integration for the bounding surface plasticity model are verified. Furthermore, the prediction for an undrained cyclic triaxial test on a saturated clay is given, and the cyclic degradation of the stiffness and strength is obtained, which indicates the validity of the computational results.%修正了传统隐式回映算法,建立了适用于饱和黏土循环动力分析的边界面塑性模型的完全隐式积分格式。该模型基于无弹性域概念和临界状态理论,采用各向同性、运动硬化准则、旋转的边界面,并引入表征土体结构损伤和重塑程度的损伤变量以反映循环载荷作用下饱和黏土的各向异性、刚度、强度软化及塑性变形累积等特征。针对等压固结K01.0和偏压固结K00.67的饱和高岭黏土的不排水三轴试验进行模拟,采用不同的应变增量步长进行计算,并与试验数据对比,结果表明,修正隐式回映算法应用于该类边界面模型的合理性、积分格式的精确性和稳定性;另外,结合有限元软件自动时间步长的

  6. The biosynthesis of cyclic carotenes.

    Science.gov (United States)

    Williams, R J; Britton, G; Goodwin, T W

    1967-10-01

    1. The incorporation of (3RS)-[2-(14)C,(4R)-4-(3)H(1)]mevalonic acid into various cyclic carotenes in the fruit of the tomato mutant delta has been studied. The results confirm our previous view that the alpha-ionone ring of alpha-carotene does not arise by isomerization of a beta-ionone residue, and show that the same is also true for the alpha-ionone ring of delta- and in-carotene and alpha-zeacarotene. 2. The incorporation of (3RS)-[2-(14)C,2-(3)H(2)]mevalonic acid into alpha- and beta-carotene in carrot roots has been studied. The results show that the beta-ionone ring of beta-carotene does not arise by isomerization of the alpha-ionone residue of alpha-carotene. 3. These experiments show that alpha- and beta-ionone rings in cyclic carotenes are formed independently, probably by elimination of different protons from the same carbonium ion intermediates.

  7. [Cyclic Cushing's Syndrome - rare or rarely recognized].

    Science.gov (United States)

    Kiałka, Marta; Doroszewska, Katarzyna; Mrozińska, Sandra; Milewicz, Tomasz; Stochmal, Ewa

    2015-01-01

    Cyclic Cushing's syndrome is a type of Cushing's disease which is characterized by alternating periods of increasing and decreasing levels of cortisol in the blood. The diagnostic criteria for cyclic Cushing's syndrome are at least three periods of hypercortisolism alternating with at least two episodes of normal levels of serum cortisol concentration. The epidemiology, signs, symptoms, pathogenesis and treatment of cyclic Cushing's syndrome have been discussed.

  8. Cyclic Cohomology of the Weyl Algebra

    CERN Document Server

    Willwacher, Thomas

    2008-01-01

    We give an explicit formula for symplectically basic representatives of the cyclic cohomology of the Weyl algebra. This paper can be seen as cyclic addendum to the paper by Feigin, Felder and Shoikhet, where the analogous Hochschild case was treated. As an application, we prove a generalization of a Theorem of Nest and Tsygan concerning the relation of the Todd class and the cyclic cohomology of the differential operators on a complex manifold.

  9. Cyclic and Inductive Calculi are equivalent

    CERN Document Server

    Voicu, Razvan

    2011-01-01

    Brotherston and Simpson [citation] have formalized and investigated cyclic reasoning, reaching the important conclusion that it is at least as powerful as inductive reasoning (specifically, they showed that each inductive proof can be translated into a cyclic proof). We add to their investigation by proving the converse of this result, namely that each inductive proof can be translated into an inductive one. This, in effect, establishes the equivalence between first order cyclic and inductive calculi.

  10. Cyclic and Inductive Calculi are equivalent

    OpenAIRE

    Razvan VOICU; Li, Mengran

    2011-01-01

    Brotherston and Simpson [citation] have formalized and investigated cyclic reasoning, reaching the important conclusion that it is at least as powerful as inductive reasoning (specifically, they showed that each inductive proof can be translated into a cyclic proof). We add to their investigation by proving the converse of this result, namely that each inductive proof can be translated into an inductive one. This, in effect, establishes the equivalence between first order cyclic and inductive...

  11. Integration Algorithm of Bounding-surface Model for Analyzing Cyclic Behaviors of Saturated Clay%饱和粘土循环动力分析边界面模型的积分算法

    Institute of Scientific and Technical Information of China (English)

    张福征; 胡存; 刘海笑

    2012-01-01

    Based on kinematic hardening rule, the bounding-surface plasticity model can be used to predict the dynamic response of saturated clay subject to cyclic loading. The numerical integration of the model is regarded as the means to evaluate offshore marine structures ,such as large-diameter cylindrical structure, the guarantee of bearing performance and dynamic response in the marine environment. The stress conversion method based on SMP rule is adopted to build a bounding-surface model which consider the tensile properties of the soil. Based on generalized trapezoidal rule, the integration algorithm of bounding-surface model is put forward to simulate the tri-axial tensile test and dynamic tri-axial test for the saturated soil. The simulation result basically accords with the geotechnical testing data.%基于运动硬化准则的新型边界面塑性模型,能够预测循环载荷作用下饱和粘土的动力响应,该模型的数值积分格式是合理评估海洋环境下大圆筒结构等近海工程结构承载性能和动力响应的保证.采用基于SMP准则的变换应力法,建立能考虑土体拉伸特性的边界面模型,根据广义梯形法则提出该模型的积分算法,模拟饱和粘土的三轴拉伸试验和动三轴试验,数值结果与土工试验数据吻合较好.

  12. Evidence that Behavioral Phenotypes of Morphine in β-arr2−/− Mice Are Due to the Unmasking of JNK Signaling

    Science.gov (United States)

    Mittal, Nitish; Tan, Miao; Egbuta, Onyemachi; Desai, Nina; Crawford, Cynthia; Xie, Cui-Wei; Evans, Christopher; Walwyn, Wendy

    2012-01-01

    The altered behavioral effects of morphine, but not most other mu agonists, in mice lacking β-arrestin 2, suggest that this scaffolding protein regulates the signaling cascade of this commonly used analgesic. One of the cascades that could be regulated by β-arrestin 2 is cJun-N-terminal kinase (JNK), which binds with β-arrestin 2 and modulates the analgesic effects of morphine. Using neurons lacking β-arrestin 2 (β-arr2−/−) to examine this interaction, we found that β-arr2−/− neurons show altered intracellular distribution of JNK and cJun, and that morphine, but not fentanyl, increased the nuclear localization of the phosphorylated, therefore activated, form of cJun, a JNK target in dorsal root ganglia neurons. This suggests that deleting β-arrestin 2 affects the JNK cascade. We therefore examined whether some of the behavioral phenotypes of mice lacking β-arrestin 2 could be a result of altered JNK signaling. Indeed, two different JNK inhibitors reversed the enhanced analgesic effect of morphine, a known phenotype of β-arr2−/− mice, to +/+ levels. Both the reduced locomotor effect of morphine and the psychomotor sensitization to repeated morphine administration in β-arr2−/− mice were also returned to +/+ levels by inhibiting JNK. In contrast, the behavioral effects of fentanyl were neither genotype-dependent nor affected by JNK inhibition. Furthermore, a PKC inhibitor had a similar effect as inhibiting JNK in reducing the enhanced analgesic effect of morphine in β-arr2−/− mice to +/+ levels. In summary, removing β-arrestin 2 reveals mu receptor activation of the JNK cascade in a ligand-specific manner explaining several behavioral phenotypes of β-arr2−/− mice. PMID:22491351

  13. Cell reorientation under cyclic stretching

    CERN Document Server

    Livne, Ariel; Geiger, Benjamin

    2014-01-01

    Mechanical cues from the extracellular microenvironment play a central role in regulating the structure, function and fate of living cells. Nevertheless, the precise nature of the mechanisms and processes underlying this crucial cellular mechanosensitivity remains a fundamental open problem. Here we provide a novel framework for addressing cellular sensitivity and response to external forces by experimentally and theoretically studying one of its most striking manifestations -- cell reorientation to a uniform angle in response to cyclic stretching of the underlying substrate. We first show that existing approaches are incompatible with our extensive measurements of cell reorientation. We then propose a fundamentally new theory that shows that dissipative relaxation of the cell's passively-stored, two-dimensional, elastic energy to its minimum actively drives the reorientation process. Our theory is in excellent quantitative agreement with the complete temporal reorientation dynamics of individual cells, measu...

  14. Modelling of Stress-Strain Relationship of Toyoura Sand in Large Cyclic Torsional Loading

    Science.gov (United States)

    Hong Nam, Nguyen; Koseki, Junichi

    The relationships between normalized shear stress and plastic shear strain of air-dried, dense Toyoura sand measured during large amplitude cyclic torsional loading with using local strain measurement could be well simulated numerically by the proportional rule combined with the drag rule. The proportional rule is an extended version of the Masing's second rule and can account for unsymmetrical stress strain behavior about neutral axis. The drag rule can account for strain hardening in cyclic loadings. Use of the newly proposed hypoelastic model for the quasi-elastic properties, the backbone curve using general hyperbolic equation or newly proposed lognormal equation for monotonic loading behavior, and the combination of the proportional rule and the drag rule for cyclic loading behavior would enable more precise simulation of deformation properties than before.

  15. Cyclic electrophoretic and chromatographic separation methods

    NARCIS (Netherlands)

    Eijkel, Jan C.T.; Berg, van den Albert; Manz, Andreas

    2004-01-01

    A review is given of the application of cyclic analytical methods in capillary electroseparation (CE) and liquid chromatography (LC) systems. Cyclic methods have been used since the early sixties in chromatographic systems to overcome pressure limitations to resolution. From the early nineties on th

  16. Cyclicality in Losses on Bank Loans

    NARCIS (Netherlands)

    B. Keijsers (Bart); B.F. Diris (Bart); H.J.W.G. Kole (Erik)

    2015-01-01

    markdownabstract__Abstract__ Cyclicality in the losses of bank loans is important for bank risk management. Because loans have a different risk profile than bonds, evidence of cyclicality in bond losses need not apply to loans. Based on unique data we show that the default rate and loss given defau

  17. Cyclic malyl anthocyanins in Dianthus caryophyllus.

    Science.gov (United States)

    Nakayama, M; Koshioka, M; Yoshida, H; Kan, Y; Fukui, Y; Koike, A; Yamaguchi, M

    2000-12-01

    3,5-Di-O-(beta-glucopyranosyl) pelargonidin 6''-O-4,6'''-O-1-cyclic malate and a previously reported cyanidin equivalent, 3,5-di-O-(beta-glucopyranosyl) cyanidin 6''-O-4,6'''-O-1-cyclic malate were identified from petals of deep pink and red-purple flower cultivars of Dianthus caryophyllus, respectively.

  18. Products in Hopf-Cyclic Cohomology

    CERN Document Server

    Kaygun, Atabey

    2007-01-01

    We construct several pairings in Hopf-cyclic cohomology of (co)module (co)algebras with arbitrary coefficients. The key ideas instrumental in constructing these pairings are the derived functor interpretation of Hopf-cyclic and equivariant cyclic (co)homology, and the Yoneda interpretation of Ext-groups. As a special case of one of these pairings, we recover the Connes-Moscovici characteristic map in Hopf-cyclic cohomology. We also prove that this particular pairing, along with few others, would stay the same if we replace the derived category of (co)cyclic modules with the homotopy category of (special) towers of $X$-complexes, or the derived category of mixed complexes.

  19. Finite element approach to study the behavior of fluid distribution in the dermal regions of human body due to thermal stress

    Directory of Open Access Journals (Sweden)

    M.A. Khanday

    2015-10-01

    Full Text Available The human body is a complex structure where the balance of mass and heat transport in all tissues is necessary for its normal functioning. The stabilities of intracellular and extracellular fluids are important physiological factors responsible for homoeostasis. To estimate the effects of thermal stress on the behavior of extracellular fluid concentration in human dermal regions, a mathematical model based on diffusion equation along with appropriate boundary conditions has been formulated. Atmospheric temperature, evaporation rate, moisture concentration and other factors affecting the fluid concentration were taken into account. The variational finite element approach has been employed to solve the model and the results were interpreted graphically.

  20. Molecular dynamics investigation of the grain boundary migration hysteresis of nanocrystalline Ni under cyclic shear loading

    Science.gov (United States)

    Wang, Peng; Yang, Xinhua; Peng, Di

    2017-02-01

    The deformation behavior and grain boundary (GB) response of nanocrystalline Ni under cyclic shear loading are investigated by molecular dynamics simulations. The GB migration hysteresis phenomenon, in which the GB migration displacement lags behind the change in nominal shear strain, is observed in the symmetric tilt GBs for the first time. The elementary structure transformation occurring at the two end segments of the observed GB during GB migration produces a disordered and irreversible state, while the transformation in the middle segment is reversible. Both dislocation retraction and nucleation occur during unloading. Relatively large cyclic strain amplitudes lead to disordered GB segments of greater length, such that the residual GB migration displacement increases with increasing cyclic amplitude. GB migration hysteresis vanishes after the GB becomes immobile owing to a cyclic shear induced transition to a disordered state along its entire length.

  1. Behavioral and Movement Disorders due to Long-Lasting Myoclonic Status Epilepticus Misdiagnosed as ADHD in a Patient With Juvenile Myoclonic Epilepsy: Electroclinical Findings and Related Hemodynamic Changes.

    Science.gov (United States)

    Fanella, Martina; Carnì, Marco; Morano, Alessandra; Albini, Mariarita; Lapenta, Leonardo; Casciato, Sara; Fattouch, Jinane; Di Castro, Elisabetta; Colonnese, Claudio; Vaudano, Anna Elisabetta; Giallonardo, Anna Teresa; Di Bonaventura, Carlo

    2016-01-01

    Epilepsy and attention-deficit/hyperactivity disorder (ADHD) likely share common underlying neural mechanisms, as often suggested by both the evidence of electroencephalography (EEG) abnormalities in ADHD patients without epilepsy and the coexistence of these 2 conditions. The differential diagnosis between epilepsy and ADHD may consequently be challenging. In this report, we describe a patient presenting with a clinical association of "tics" and behavioral disorders that appeared 6 months before our first observation and had previously been interpreted as ADHD. A video-EEG evaluation documented an electroclinical pattern of myoclonic status epilepticus. On the basis of the revised clinical data, the EEG findings, the good response to valproate, the long-lasting myoclonic status epilepticus, and the enduring epileptic abnormalities likely causing behavioral disturbances, the patient's symptoms were interpreted as being the expression of untreated juvenile myoclonic epilepsy. The EEG-functional magnetic resonance imaging study revealed, during clinical generalized spike-and-wave and polyspike-and-wave discharges, positive blood oxygen level-dependent (BOLD) signal changes bilaterally in the thalamus, the prefrontal cortex (Brodmann area 6, supplementary motor area) and the cerebellum, and negative BOLD signal changes in the regions of the default mode network. Such findings, which are typical of BOLD changes observed in idiopathic generalized epilepsy, may also shed light on the anatomofunctional network underlying ADHD. © EEG and Clinical Neuroscience Society (ECNS) 2015.

  2. Application of cyclic J-integral to low cycle fatigue crack growth of Japanese carbon steel pipe

    Energy Technology Data Exchange (ETDEWEB)

    Miura, N.; Fujioka, T.; Kashima, K. [and others

    1997-04-01

    Piping for LWR power plants is required to satisfy the LBB concept for postulated (not actual) defects. With this in mind, research has so far been conducted on the fatigue crack growth under cyclic loading, and on the ductile crack growth under excessive loading. It is important, however, for the evaluation of the piping structural integrity under seismic loading condition, to understand the fracture behavior under dynamic and cyclic loading conditions, that accompanies large-scale yielding. CRIEPI together with Hitachi have started a collaborative research program on dynamic and/or cyclic fracture of Japanese carbon steel (STS410) pipes in 1991. Fundamental tensile property tests were conducted to examine the effect of strain rate on tensile properties. Cracked pipe fracture tests under some loading conditions were also performed to investigate the effect of dynamic and/or cyclic loading on fracture behavior. Based on the analytical considerations for the above tests, the method to evaluate the failure life for a cracked pipe under cyclic loading was developed and verified. Cyclic J-integral was introduced to predict cyclic crack growth up to failure. This report presents the results of tensile property tests, cracked pipe fracture tests, and failure life analysis. The proposed method was applied to the cracked pipe fracture tests. The effect of dynamic and/or cyclic loading on pipe fracture was also investigated.

  3. Cyclic imines: chemistry and mechanism of action: a review.

    Science.gov (United States)

    Otero, Alberto; Chapela, María-José; Atanassova, Miroslava; Vieites, Juan M; Cabado, Ana G

    2011-11-21

    In recent years, there has been an increase in the production of shellfish and in global demand for seafood as nutritious and healthy food. Unfortunately, a significant number of incidences of shellfish poisoning occur worldwide, and microalgae that produce phycotoxins are responsible for most of these. Phycotoxins include several groups of small to medium sized natural products with molecular masses ranging from 300 to over 3000 Da. Cyclic imines (CIs) are a recently discovered group of marine biotoxins characterized by their fast acting toxicity, inducing a characteristic rapid death in the intraperitoneal mouse bioassay. These toxins are macrocyclic compounds with imine (carbon-nitrogen double bond) and spiro-linked ether moieties. They are grouped together due to the imino group functioning as their common pharmacore and due to the similarities in their intraperitoneal toxicity in mice. Spirolides (SPXs) are the largest group of CIs cyclic imines that together with gymnodimines (GYMs) are best characterized. Although the amount of cyclic imines in shellfish is not regulated and these substances have not been categorically linked to human intoxication, they trigger high intraperitoneal toxicity in rodents. In this review, the corresponding chemical structures of each member of the CIs and their derivatives are reviewed as well as all the data accumulated on their mechanism of action at cellular level.

  4. Challenges related to flotation cleaning of oil shales. Issues due to compositional and surface features and post-grinding surface behavior

    OpenAIRE

    Altun N. Emre

    2016-01-01

    Oil shale is an important energy resource alternative. Despite its recognition as an unconventional oil source, oil shale is also considered as an important solid fossil fuel alternative to coal and lignites due to the solid form and remarkable extent of organic content. Utilization possibilites, similar to coal and lignites, have been considered in the past decades and direct use of oil shales in thermal power production has been possible in countries like Estonia and China. In the perspecti...

  5. Cyclic sciatica caused by infiltrative endometriosis: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Yekeler, Ensar; Kumbasar, Basak; Tunaci, Atadan; Barman, Ahmet; Tunaci, Mehtap [Department of Radiology, Istanbul Faculty of Medicine, Istanbul University, 34390, Capa, Istanbul (Turkey); Bengisu, Ergin [Department of Obstetrics and Gynecology, Istanbul Faculty of Medicine, Istanbul University, Istanbul (Turkey); Yavuz, Ekrem [Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, 34390, Capa, Istanbul (Turkey)

    2004-03-01

    Endometriosis, an important gynecological disorder of reproductive women, affects most commonly the ovaries and less frequently the gastrointestinal tract, chest, urinary tract, and soft tissues. Endometriosis classically appears on MRI as a mass with a large cystic component and variable signal intensities on T1- and T2-weighted images due to the presence of variable degradation of hemorrhagic products. Endometriosis in an atypical location, an infiltrative appearance and without cystic-hemorrhagic components has rarely been described. We report on a 33-year-old woman with cyclic sciatica due to histologically documented infiltrative endometriosis involving the area of the left sciatic notch. (orig.)

  6. Resurgence of oscillation in coupled oscillators under delayed cyclic interaction

    Science.gov (United States)

    Bera, Bidesh K.; Majhi, Soumen; Ghosh, Dibakar

    2017-07-01

    This paper investigates the emergence of amplitude death and revival of oscillations from the suppression states in a system of coupled dynamical units interacting through delayed cyclic mode. In order to resurrect the oscillation from amplitude death state, we introduce asymmetry and feedback parameter in the cyclic coupling forms as a result of which the death region shrinks due to higher asymmetry and lower feedback parameter values for coupled oscillatory systems. Some analytical conditions are derived for amplitude death and revival of oscillations in two coupled limit cycle oscillators and corresponding numerical simulations confirm the obtained theoretical results. We also report that the death state and revival of oscillations from quenched state are possible in the network of identical coupled oscillators. The proposed mechanism has also been examined using chaotic Lorenz oscillator.

  7. Low Cycle Fatigue of Steel in Strain Controled Cyclic Bending

    Directory of Open Access Journals (Sweden)

    Kulesa Anna

    2016-03-01

    Full Text Available The paper presents a comparison of the fatigue life curves based on test of 15Mo3 steel under cyclic, pendulum bending and tension-compression. These studies were analyzed in terms of a large and small number of cycles where strain amplitude is dependent on the fatigue life. It has been shown that commonly used Manson-Coffin-Basquin model cannot be used for tests under cyclic bending due to the impossibility of separating elastic and plastic strains. For this purpose, some well-known models of Langer and Kandil and one new model of authors, where strain amplitude is dependent on the number of cycles, were proposed. Comparing the results of bending with tension-compression it was shown that for smaller strain amplitudes the fatigue life for both test methods were similar, for higher strain amplitudes fatigue life for bending tests was greater than for tension-compression.

  8. Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection

    Directory of Open Access Journals (Sweden)

    Hwang Jong-Hee

    2008-10-01

    Full Text Available Abstract Background Worldwide, approximately two billion people are chronically infected with Toxoplasma gondii with largely unknown consequences. Methods To better understand long-term effects and pathogenesis of this common, persistent brain infection, mice were infected at a time in human years equivalent to early to mid adulthood and studied 5–12 months later. Appearance, behavior, neurologic function and brain MRIs were studied. Additional analyses of pathogenesis included: correlation of brain weight and neurologic findings; histopathology focusing on brain regions; full genome microarrays; immunohistochemistry characterizing inflammatory cells; determination of presence of tachyzoites and bradyzoites; electron microscopy; and study of markers of inflammation in serum. Histopathology in genetically resistant mice and cytokine and NRAMP knockout mice, effects of inoculation of isolated parasites, and treatment with sulfadiazine or αPD1 ligand were studied. Results Twelve months after infection, a time equivalent to middle to early elderly ages, mice had behavioral and neurological deficits, and brain MRIs showed mild to moderate ventricular dilatation. Lower brain weight correlated with greater magnitude of neurologic abnormalities and inflammation. Full genome microarrays of brains reflected inflammation causing neuronal damage (Gfap, effects on host cell protein processing (ubiquitin ligase, synapse remodeling (Complement 1q, and also increased expression of PD-1L (a ligand that allows persistent LCMV brain infection and CD 36 (a fatty acid translocase and oxidized LDL receptor that mediates innate immune response to beta amyloid which is associated with pro-inflammation in Alzheimer's disease. Immunostaining detected no inflammation around intra-neuronal cysts, practically no free tachyzoites, and only rare bradyzoites. Nonetheless, there were perivascular, leptomeningeal inflammatory cells, particularly contiguous to the aqueduct of

  9. Specificity of the Cyclic GMP-Binding Activity and of a Cyclic GMP-Dependent Cyclic GMP Phosphodiesterase in Dictyostelium discoideum

    NARCIS (Netherlands)

    Haastert, Peter J.M. van; Walsum, Hans van; Meer, Rob C. van der; Bulgakov, Roman; Konijn, Theo M.

    1982-01-01

    The nucleotide specificity of the cyclic GMP-binding activity in a homogenate of Dictyostelium discoideum was determined by competition of cyclic GMP derivatives with [8-3H] cyclic GMP for the binding sites. The results indicate that cyclic GMP is bound to the binding proteins by hydrogen bonds at N

  10. Effect of Cyclic Thermo-Mechanical Loads on Fatigue Reliability in Polymer Matrix Composites

    Science.gov (United States)

    Shah, A. R.; Murthy, P. L. N.; Chamis, C. C.

    1996-01-01

    A methodology to compute probabilistic fatigue life of polymer matrix laminated composites has been developed and demonstrated. Matrix degradation effects caused by long term environmental exposure and mechanical/thermal cyclic loads are accounted for in the simulation process. A unified time-temperature-stress dependent multi-factor interaction relationship developed at NASA Lewis Research Center has been used to model the degradation/aging of material properties due to cyclic loads. The fast probability integration method is used to compute probabilistic distribution of response. Sensitivities of fatigue life reliability to uncertainties in the primitive random variables (e.g., constituent properties, fiber volume ratio, void volume ratio, ply thickness, etc.) computed and their significance in the reliability- based design for maximum life is discussed. The effect of variation in the thermal cyclic loads on the fatigue reliability for a (0/+/- 45/90)(sub s) graphite/epoxy laminate with a ply thickness of 0.127 mm, with respect to impending failure modes has been studied. The results show that, at low mechanical cyclic loads and low thermal cyclic amplitudes, fatigue life for 0.999 reliability is most sensitive to matrix compressive strength, matrix modulus, thermal expansion coefficient, and ply thickness. Whereas at high mechanical cyclic loads and high thermal cyclic amplitudes, fatigue life at 0.999 reliability is more sensitive to the shear strength of matrix, longitudinal fiber modulus, matrix modulus, and ply thickness.

  11. Probabilistic Simulation of Combined Thermo-Mechanical Cyclic Fatigue in Composites

    Science.gov (United States)

    Chamis, Christos C.

    2011-01-01

    A methodology to compute probabilistically-combined thermo-mechanical fatigue life of polymer matrix laminated composites has been developed and is demonstrated. Matrix degradation effects caused by long-term environmental exposure and mechanical/thermal cyclic loads are accounted for in the simulation process. A unified time-temperature-stress-dependent multifactor-interaction relationship developed at NASA Glenn Research Center has been used to model the degradation/aging of material properties due to cyclic loads. The fast probability-integration method is used to compute probabilistic distribution of response. Sensitivities of fatigue life reliability to uncertainties in the primitive random variables (e.g., constituent properties, fiber volume ratio, void volume ratio, ply thickness, etc.) computed and their significance in the reliability-based design for maximum life is discussed. The effect of variation in the thermal cyclic loads on the fatigue reliability for a (0/+/-45/90)s graphite/epoxy laminate with a ply thickness of 0.127 mm, with respect to impending failure modes has been studied. The results show that, at low mechanical-cyclic loads and low thermal-cyclic amplitudes, fatigue life for 0.999 reliability is most sensitive to matrix compressive strength, matrix modulus, thermal expansion coefficient, and ply thickness. Whereas at high mechanical-cyclic loads and high thermal-cyclic amplitudes, fatigue life at 0.999 reliability is more sensitive to the shear strength of matrix, longitudinal fiber modulus, matrix modulus, and ply thickness.

  12. Cyclic deformation behaviour of naturalK0-consolidated soft clay under different stress paths

    Institute of Scientific and Technical Information of China (English)

    孙磊; 蔡袁强; 谷川; 王军; 郭林

    2015-01-01

    Characteristic of cyclic loading due to passing wheels is associated with one-way loading without stress reversal, which includes a simultaneous cyclic variation of vertical normal stress and horizontal normal stress lasting for a long period of time and generally takes place in partially-drained conditions. Therefore, it is of great practical relevance to study the deformation behaviour according to the characteristic of traffic loading. In this work, a series of one-way stress-controlled cyclic triaxial tests with a simultaneous variation of the vertical and horizontal stress components during cyclic loading were conducted to investigate the deformation behaviour of naturalK0-consolidated soft clay in partially-drained conditions. Test results demonstrate that not only the deviator part of the stress rules accumulation but also the volumetric part significantly contributes. While the deviator part of the stress amplitude is held constant, the increase amplitude of cyclic confining pressure will promote the development of both permanent volumetric strain and axial strain significantly. Furthermore, the effects of cyclic confining pressure on the deformation of naturalK0-consolidated soft clay was quantified. Finally, an empirical formula for permanent axial strain considering the effects of cyclic confining pressure was proposed which can be used for feasibility studies or for the preliminary design of foundations on K0-consolidated soft clay subjected to traffic loading.

  13. FINITE ELEMENT ANALYSIS OF CARDIAC MYOCYTE DEBONDING AND REORIENTATION DURING CYCLIC SUBSTRATE STRETCH EXPERIMENTS

    Institute of Scientific and Technical Information of China (English)

    Tao Tang; Jun Qiu; Meng Zhang; Zhuo Zhuang

    2009-01-01

    The substrate stretch experiment, which is carried out on several kinds of adherent cells, is usually used to catch the physiological variation and morphological response to cyclic substrate deformation. In this paper, stretch loading was exerted on cardiac myocytes cultured on silica substrates using a custom-made substrate stretch device. The effect of stretch on the alignment orientation of cardiac myocytes was studied through morphocytological statistics. Under cyclic stretch stimulus, the long axes of cardiac myocytes oriented perpendicularly to the stretch direction for continuous stretch acting. However, the mechanism underlying these behaviors is not well understood from such in vitro tests. Finite element (FE) model was developed in the analysis to investigate these behaviors. Xu-Needleman formulation was used to define the interaction behavior for contact surfaces between cell and substrate. The role of cell viscoelasticity nature is studied in adherent cell debonding with the substrate and aligning perpendicular to the stretch direction during long time cyclic stretch stimulation. There were four different strain magnitudes considered in the simulation to find out the cell debonding affected by the cyclic strains. The potential role of cyclic strain frequency in regulating cell debonding and alignment was also studied using FE analysis.

  14. Study of the electrochemical behavior of the niobium in relation to the hydrogen cyclical charge and uncharge; Estudo do comportamento eletroquimico do niobio em relacao ao carregamento e descarregamento ciclicos de hidrogenio

    Energy Technology Data Exchange (ETDEWEB)

    Silva, A.G.S.G. da; Ponte, H.A.; Pashchuk, A. [Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil). Centro Politecnico. Lab. de Eletroquimica de Superficie e Corrosao (LESK)], e-mail: aleksantos@hotmail.com

    2006-07-01

    One of the greatest problems found in the oil industry is the control of the deterioration at the steels structures of the units that compose the process petroleum refine. This deterioration is related the mechanisms involving processes of hydrogen embrittlement. The work had as objective to study the electrochemical behavior of the niobium (Nb) with relation to the charging and uncharging of hydrogen, to evaluate the potential to use of the Nb in the construction of electrochemical hydrogen probes. For this study techniques of cronopotenciometry and potential of open circuit (OCP) for the pure Nb submitted the different hydrogen charging conditions had been used. The gotten partial results indicate the viability to use of the niobium as hydrogen probe, however, it is necessary one better understanding of the mechanisms of hydrogen interaction with the niobium. (author)

  15. General solution of cyclic Leibniz rule

    CERN Document Server

    Kadoh, Daisuke

    2015-01-01

    We study the general solution of the cyclic Leibniz rule (CLR) which was recently proposed as a new approach to the lattice supersymmetry. Introducing some mathematical preliminaries associated with the cyclic symmetry, we find the general solution of the 2-body CLR for the naive symmetric difference operator. The main theorems of this paper state that the general solution can be uniquely expressed as (A) a linear combination of the two fundamental solutions with cyclic invariant coefficients, and (B) a linear combination of the minimal solutions with complex coefficients. Moreover, an extension to the general difference operators is also discussed.

  16. Monopod bucket foundations under cyclic lateral loading

    OpenAIRE

    Foglia, Aligi; Ibsen, Lars Bo

    2014-01-01

    The monopod bucket foundation can be a cost-reducing sub-structure for offshore wind turbines. To avoid problems during the turbine operation, the long-term effect of cyclic loading must be considered in the design of the foundation. In this paper a 1g testing rig is adopted to extend the knowledge on bucket foundations under lateral cyclic loading. The test setup is described in detail and a comprehensive experimental campaign is presented. The foundation is subjected to cyclic overturning m...

  17. Cyclic Control Optimization for a Smart Rotor

    DEFF Research Database (Denmark)

    Bergami, Leonardo; Henriksen, Lars Christian

    2012-01-01

    The paper presents a method to determine cyclic control trajectories for a smart rotor undergoing periodic-deterministic load variations. The control trajectories result from a constrained optimization problem, where the cost function to minimize is given by the variation of the blade root flapwise...... bending moment within a rotor revolution. The method is applied to a rotor equipped with trailing edge flaps, and capable of individual blade pitching. Results show that the optimized cyclic control significantly alleviates the load variations from periodic disturbances; the combination of both cyclic...

  18. Effect of psychological stress on the content of plasma cyclic nucleotide in individuals of different behavior types%心理应激对不同行为类型者血浆环核苷酸含量的影响

    Institute of Scientific and Technical Information of China (English)

    张爱华; 周力; 李佩贤; 徐丽华; 王力

    2004-01-01

    BACKGROUND: Research on coronary heart disease(CHD) mediator based on molecular biology is scarce, however, it is very helpful for the prevention and control of CHD on that level.OBJECTIVE: To find out the changes of plasma cyclic nucleotide in individuals of different behavior types so as to provide prospective data for the research of mediator of psychological factors inducing CHD.DESIGN: A prospective study.SETTING, PARTICIPANTS and INTERVENTION: Type A and Bbehaviour examinees, 19 respectively, were selected at random from 300 volunteers by questionnaire. Their venous bloods were collected at 16:30 to 17:00 80 days and 1 hour before examination respectively in Weifang First Middle School. Content of plasma cyclic nucleotide were assayed to observe the effect of psychological stress (university entrance examination is the stress origin) on individuals in different behavior types.MAIN OUTCOME MEASURES: Content of plasma cyclic nucleotide before and after stress respectively.RESULTS: Beforo the stress, content of plasma cyclic adenosine monophosphate(cAMP) [ (15.46 ± 3.56) nmol/L] of type A was significantly higher than type B[ (12.09 + 2.78) nmol/L], and this distinction had quite remarkable meanings( t = 3.25, P < 0. 01 ). After the stress, the plasma cAMP and cAMP/cGMP content in type A decreased compared with that before strcss[ (10.911 +3.950), (5.526 + 1.488) nmol/L respectively], and the differeces were significant( t = 12. 25, 8. 14, P < 0. 001), meanwhile, cGMP increased[ (2. 962 + 0. 764)nmol/L] ( t = - 9.06, P < 0. 001 ); the plasma cAMP and cAMP/cGMP in type B decreased[ (7.379 ± 1.762), (3.677 ±1.488) mmol/L] (t =7.42, 7.56, P < 0.001), while cGMP increased [ (2.280 ± 0.685 ) nmol / L ] ( t = - 7.52, P < 0.001 ). The decrease range of cAMP and Camp/cGMP in type A were significantly higher than that in type B(t =3.56,3.83, P <0.001).CONCLUSION: Effect of stress caused by college entrance examination on the content of plasma cyclic

  19. Recent progress on weight distributions of cyclic codes over finite fields

    Directory of Open Access Journals (Sweden)

    Hai Q. Dinh

    2015-01-01

    Full Text Available Cyclic codes are an interesting type of linear codes and have wide applications in communication and storage systems due to their efficient encoding and decoding algorithms. In coding theory it is often desirable to know the weight distribution of a cyclic code to estimate the error correcting capability and error probability. In this paper, we present the recent progress on the weight distributions of cyclic codes over finite fields, which had been determined by exponential sums. The cyclic codes with few weights which are very useful are discussed and their existence conditions are listed. Furthermore, we discuss the more general case of constacyclic codes and give some equivalences to characterize their weight distributions.

  20. Review cyclic peptides on a merry-go-round; towards drug design.

    Science.gov (United States)

    Tapeinou, Anthi; Matsoukas, Minos-Timotheos; Simal, Carmen; Tselios, Theodore

    2015-09-01

    Peptides and proteins are attractive initial leads for the rational design of bioactive molecules. Several natural cyclic peptides have recently emerged as templates for drug design due to their resistance to chemical or enzymatic hydrolysis and high selectivity to receptors. The development of practical protocols that mimic the power of nature's strategies remains paramount for the advancement of novel peptide-based drugs. The de novo design of peptide mimetics (nonpeptide molecules or cyclic peptides) for the synthesis of linear or cyclic peptides has enhanced the progress of therapeutics and diverse areas of science and technology. In the case of metabolically unstable peptide ligands, the rational design and synthesis of cyclic peptide analogues has turned into an alternative approach for improved biological activity.

  1. Change in pharmacokinetic behavior of intravenously administered midazolam due to increased CYP3A2 expression in rats treated with menthol.

    Science.gov (United States)

    Nagai, Katsuhito; Suzuki, Sho; Yamamura, Ayumi; Konishi, Hiroki

    2015-04-01

    Menthol is used widely as a constituent of functional foods and chemical drugs. The present study investigated changes in the pharmacokinetic behavior of intravenously administered midazolam (MDZ), a probe for CYP3A, when rats were treated with menthol. The study also examined which isoforms of CYP3A1 and 3A2 were menthol-inducible and contributed to the altered disposition of midazolam. Menthol was administered intraperitoneally to rats once daily for 3 days at a dose of 10 mg/kg, while the control rats received vehicle alone. The pharmacokinetic examination of i.v. administered midazolam revealed that serum midazolam concentrations at each sampling point were lower in the menthol-treated rats than in the control rats. Regarding the pharmacokinetic parameters of the menthol-treated group, the area under the curve (AUC) was decreased significantly and, correspondingly, the elimination rate constant at terminal phase (ke) was increased significantly without significant changes in the volume of distribution at steady state (Vdss). The metabolic production of the 1'-hydroxylated and 4'-hydroxylated forms of MDZ by hepatic microsomes was significantly greater in the menthol-treated rats than in the control rats. The expression levels of mRNA and protein for hepatic CYP3A2 were more than 2.5-fold higher than the control levels when the rats were treated with menthol, whereas no changes were observed in the expression levels of CYP3A1. These results indicate that menthol enhanced the elimination clearance of midazolam by inducing hepatic CYP3A2 and that careful attention should be paid when menthol is ingested in combination with drugs that act as substrates for CYP3A.

  2. Experimental Investigations of Tension Piles in Sand Subjected to Static and Cyclic Loading

    DEFF Research Database (Denmark)

    Thomassen, Kristina

    The present thesis regards the behavior of the piles in jacket pile foundations used for offshore wind turbines. The piles are often loaded in tension because of the combination of wind and wave conditions and the low self-weight of the wind turbine. The repeated cyclic loading can lead...... to accumulated upwards displacement of the piles and, thus, undesired deflection of the wind turbine structure. This study concerns the effect of cyclic loading on a pile installed in dense sand and loaded in tension. A new laboratory test setup was constructed to make these pile load tests. The thesis discusses...... the advantages and disadvantages of the test setup. The results of cyclic loading tests showed that the loading conditions are very important for the behavior of piles. Some wind and wave conditions can be beneficial and increase the pile capacity while other conditions can be damaging and reduce the pile...

  3. Investigation on the radiation induced conductivity of space-applied polyimide under cyclic electron irradiation

    Science.gov (United States)

    Yue, Long; Wu, Yiyong; Sun, Chengyue; Xiao, Jingdong; Shi, Yaping; Ma, Guoliang; He, Shiyu

    2012-11-01

    Radiation induced conductivity (RIC) is an important property of dielectric materials to evaluate the charge/discharge effect in orbit-service spacecraft. RIC of space-applied polyimide film was in situ measured and studied under continuous and cyclic electron irradiation in this paper. The results indicate that, for cyclic electron irradiation, there is a similar increasing-mode of RIC to those for continuous irradiation with the electron irradiation time. However, under the cyclic electron irradiation, the RIC of polyimide shows an obvious irradiation-history characteristic, namely preliminary irradiation dose effect (PIDE). In this case, the steady RIC value presents an "overshoot" behavior in the first few irradiation cycles and then decrease to a stable one as that under continuous irradiation. Prolonging the initial irradiation duration may avoid occurrence of overshoot phenomenon. The behaviors of irradiation-induced free radicals in polyimide could be applied to explain the RIC evolution processes.

  4. The effect of cyclic torsion on the dislocation structure of drawn mild steel

    Directory of Open Access Journals (Sweden)

    Maria Teresa Paulino Aguilar

    2006-09-01

    Full Text Available Cold forming is usually associated with the "work hardening" of the material being formed. The work hardening behavior of metals subject to complex processing paths is different from that in monotonic deformation. The results show that, after some initial hardening, there is a possibility that further deformation will cause softening in the material ("work softening". Recent work showed that cyclic torsion applied to drawn products causes changes in the subsequent tensile behavior of low carbon steel, and that the effect will depend on the previous "history" of the material. For annealed samples, the cyclic torsion leads to an increase in the yield strength, but does not affect the tensile strength and elongation. For the case of previously drawn bars, the cyclic deformation caused a decrease in the yield and tensile strength and an increase in the total elongation. The present paper discusses the dislocation structure changes associated with different strain paths in mild steel.

  5. Mechanical behavior of concrete and related porous materials under partial saturation: The effective stress and the viscous softening due to movement of nanometer-scale pore fluid

    Science.gov (United States)

    Vlahinic, Ivan

    It has been said that porous materials are like music: the gaps are as important as the filled-in bits. In other words, in addition to the solid structure, pore characteristics such as size and morphology play a crucial role in defining the overall physical properties of the porous materials. This work goes a step further and examines the behaviors of some porous media that arise when the pore network is occupied by two fluids, principally air and water, as a result of drying or wetting. Such a state gives rise to fluid capillarity which can generate significant negative fluid pressures. In the first part, a constitutive model for drying of an elastic porous medium is proposed and then extended to derive a novel expression for effective stress in partially saturated media. The model is motivated by the fact that in a system that is saturated by two different fluids, two different pressure inherently act on the surfaces of the pore network. This causes a non-uniform strain field in the solid structure, something that is not explicitly accounted for in the classic formulations of this problem. We use some standard micromechanical homogenization techniques to estimate the extent of the 'non-uniformity' and on this basis, evaluate the validity of the classic Bishop effective stress expression for partially saturated materials. In the second part, we examine a diverse class of porous materials which behave in an unexpected (and even counterintuitive) way under the internal moisture fluctuations. In particular, during wetting and drying alike, the solid viscosity of these materials appears to soften, sometimes by an order of magnitude or more. Under load, this can lead to significantly increased rates of deformations. On account of the recent experimental and theoretical findings on the nature of water flow in nanometer-size hydrophillic spaces, we provide a physical explanation for the viscous softening and propose a constitutive law on this basis. To this end, it also

  6. Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits

    Directory of Open Access Journals (Sweden)

    Zhao Y

    2015-02-01

    Full Text Available Yu Zhao,1 Ming Xiao,2 Wenbo He,3 Zhiyou Cai3 1Department of Neurology, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 2Department of Anatomy, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 3Department of Neurology, Renmin Hospital, Hubei University of Medicine, Shiyan Renmin Hospital, Shiyan, Hubei Province, People’s Republic of China Background and purpose: The cAMP response element binding protein (CREB plays an important role in the mechanism of cognitive impairment and is also pivotal in the switch from short-term to long-term memory. Brain-derived neurotrophic factor (BDNF seems a promising avenue in the treatment of cerebral ischemia injury since this neurotrophin could stimulate structural plasticity and repair cognitive impairment. Several findings have displayed that the dysregulation of the CREB–BDNF cascade has been involved in cognitive impairment. The aim of this study was to investigate the effect of cerebral ischemia on learning and memory as well as on the levels of CREB, phosphorylated CREB (pCREB, and BDNF, and to determine the effect of minocycline on CREB, pCREB, BDNF, and behavioral functional recovery after cerebral ischemia. Methods: The animal model was established by permanent bilateral occlusion of both common carotid arteries. Behavior was evaluated 5 days before decapitation with Morris water maze and open-field task. Four days after permanent bilateral occlusion of both common carotid arteries, minocycline was administered by douche via the stomach for 4 weeks. CREB and pCREB were examined by Western blotting, reverse transcription polymerase chain reaction, and immunohistochemistry. BDNF was measured by immunohistochemistry and Western blotting. Results: The model rats after minocycline treatment swam shorter distances than control rats before finding the platform (P=0.0007. The number of times the

  7. The Permutation Groups and the Equivalence of Cyclic and Quasi-Cyclic Codes

    CERN Document Server

    Guenda, Kenza

    2010-01-01

    We give the class of finite groups which arise as the permutation groups of cyclic codes over finite fields. Furthermore, we extend the results of Brand and Huffman et al. and we find the properties of the set of permutations by which two cyclic codes of length p^r can be equivalent. We also find the set of permutations by which two quasi-cyclic codes can be equivalent.

  8. Cyclic Oxonitriles: Stereodivergent Grignard Addition-Alkylations

    OpenAIRE

    Fleming, Fraser F.; Wei, Guoqing; Zhang, Zhiyu; Steward, Omar W.

    2007-01-01

    Sequential carbonyl addition-conjugate addition of Grignard reagents to cyclic 5–7–membered oxoalkenenitriles efficiently generates cyclic magnesiated nitriles. Alkylations of these magnesiated nitriles exhibit diastereoselectivities that depend intimately on the size of the carbocyclic ring: 5-membered oxonitriles generate magnesiated nitriles whose alkylations are controlled by steric constraints whereas 6- and 7-membered oxonitriles generate internally coordinated, C-magnesiated nitriles w...

  9. Total synthesis of cyclic heptapeptide euryjanicin B

    Institute of Scientific and Technical Information of China (English)

    Chun Mei Zhang; Jun Xiang Guo; Liang Wang; Xiao Yun Chai; Hong Gang Hu; Qiu Ye Wu

    2011-01-01

    The first synthesis of the naturally occurring cyclic peptide euryjanicin B has been achieved. A general method was described to synthesize the cyclic peptide by a two-step solid-phase/solution synthesis strategy. All the amino acids in this study are L-configuration, The linear heptapeptide was assembled by standard Fmoc chemistry on solid-phase and subsequently cyclization was carried out by solution method.

  10. Cyclic Period in the CBE Model

    CERN Document Server

    Frampton, Paul H

    2016-01-01

    In a cyclic entropy model in which the extroverse is jettisoned at turnaround with a Come Back Empty (CBE) assumption, we address matching of the contaction scale factor $\\hat{a}(t)=f(t_T){a}(t)$ to the expansion scale factor $a(t)$, where $f(t_T)$ is the ratio at turnaround of the introverse to extroverse radii. Such matching is necessary for infinite cyclicity and fixes the CBE period at $\\sim 2.6Ty$.

  11. Synthesis of Chiral Amino Cyclic Phosphoric Acids

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Chirai amino cyclic phosphoric acids, 5-amino-2-hydroxy-4- (4-nitrophenyl)-l, 3,2-dioxaphospho- rinane 2-oxide and 2-hydroxy-4- (4-methylsulfonylphenyl)-5-phthalimido-1,3,2-dioxaphos phorinane 2-oxide are synthesized in good over yields (64. 2% and 72. 8% respectively) from 2-amino-l-aryl-l,3-propanediols. The different reaction conditions are necessary in hydrolysis reactions of amino cyclic phosphonyl chlorides.

  12. Inverse strain rate effect on cyclic stress response in annealed Zircaloy-2

    Energy Technology Data Exchange (ETDEWEB)

    Sudhakar Rao, G.; Verma, Preeti [Center of Advanced Study, Department of Metallurgical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi 221005 (India); Chakravartty, J.K. [Mechanical Metallurgy Group, Bhabha Atomic Research Center, Trombay 400 085, Mumbai (India); Nudurupati, Saibaba [Nuclear Fuel Complex, Hyderabad 500 062 (India); Mahobia, G.S.; Santhi Srinivas, N.C. [Center of Advanced Study, Department of Metallurgical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi 221005 (India); Singh, Vakil, E-mail: vsingh.met@itbhu.ac.in [Center of Advanced Study, Department of Metallurgical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi 221005 (India)

    2015-02-15

    Low cycle fatigue behavior of annealed Zircaloy-2 was investigated at 300 and 400 °C at different strain amplitudes and strain rates of 10{sup −2}, 10{sup −3}, and 10{sup −4} s{sup −1}. Cyclic stress response showed initial hardening with decreasing rate of hardening, followed by linear cyclic hardening and finally secondary hardening with increasing rate of hardening for low strain amplitudes at both the temperatures. The rate as well the degree of linear hardening and secondary hardening decreased with decrease in strain rate at 300 °C, however, there was inverse effect of strain rate on cyclic stress response at 400 °C and cyclic stress was increased with decrease in strain rate. The fatigue life decreased with decrease in strain rate at both the temperatures. The occurrence of linear cyclic hardening, inverse effect of strain rate on cyclic stress response and deterioration in fatigue life with decrease in strain rate may be attributed to dynamic strain aging phenomena resulting from enhanced interaction of dislocations with solutes. Fracture surfaces revealed distinct striations, secondary cracking, and oxidation with decrease in strain rate. Deformation substructure showed parallel dislocation lines and dislocation band structure at 300 °C. Persistent slip band wall structure and development of fine Corduroy structure was observed at 400 °C.

  13. Coping with cyclic oxygen availability: evolutionary aspects.

    Science.gov (United States)

    Flück, Martin; Webster, Keith A; Graham, Jeffrey; Giomi, Folco; Gerlach, Frank; Schmitz, Anke

    2007-10-01

    Both the gradual rise in atmospheric oxygen over the Proterozoic Eon as well as episodic fluctuations in oxygen over several million-year time spans during the Phanerozoic Era, have arguably exerted strong selective forces on cellular and organismic respiratory specialization and evolution. The rise in atmospheric oxygen, some 2 billion years after the origin of life, dramatically altered cell biology and set the stage for the appearance of multicelluar life forms in the Vendian (Ediacaran) Period of the Neoproterozoic Era. Over much of the Paleozoic, the level of oxygen in the atmosphere was near the present atmospheric level (21%). In the Late Paleozoic, however, there were extended times during which the level of atmospheric oxygen was either markedly lower or markedly higher than 21%. That these Paleozoic shifts in atmospheric oxygen affected the biota is suggested by the correlations between: (1) Reduced oxygen and the occurrences of extinctions, a lowered biodiversity and shifts in phyletic succession, and (2) During hyperoxia, the corresponding occurrence of phenomena such as arthropod gigantism, the origin of insect flight, and the evolution of vertebrate terrestriality. Basic similarities in features of adaptation to hyopoxia, manifest in living organisms at levels ranging from genetic and cellular to physiological and behavioral, suggest the common and early origin of a suite of adaptive mechanisms responsive to fluctuations in ambient oxygen. Comparative integrative approaches addressing the molecular bases of phenotypic adjustments to cyclic oxygen fluctuation provide broad insight into the incremental steps leading to the early evolution of homeostatic respiratory mechanisms and to the specialization of organismic respiratory function.

  14. Antimicrobial cyclic peptides for plant disease control.

    Science.gov (United States)

    Lee, Dong Wan; Kim, Beom Seok

    2015-03-01

    Antimicrobial cyclic peptides derived from microbes bind stably with target sites, have a tolerance to hydrolysis by proteases, and a favorable degradability under field conditions, which make them an attractive proposition for use as agricultural fungicides. Antimicrobial cyclic peptides are classified according to the types of bonds within the ring structure; homodetic, heterodetic, and complex cyclic peptides, which in turn reflect diverse physicochemical features. Most antimicrobial cyclic peptides affect the integrity of the cell envelope. This is achieved through direct interaction with the cell membrane or disturbance of the cell wall and membrane component biosynthesis such as chitin, glucan, and sphingolipid. These are specific and selective targets providing reliable activity and safety for non-target organisms. Synthetic cyclic peptides produced through combinatorial chemistry offer an alternative approach to develop antimicrobials for agricultural uses. Those synthesized so far have been studied for antibacterial activity, however, the recent advancements in powerful technologies now promise to provide novel antimicrobial cyclic peptides that are yet to be discovered from natural resources.

  15. Antimicrobial Cyclic Peptides for Plant Disease Control

    Directory of Open Access Journals (Sweden)

    Dong Wan Lee

    2015-03-01

    Full Text Available Antimicrobial cyclic peptides derived from microbes bind stably with target sites, have a tolerance to hydrolysis by proteases, and a favorable degradability under field conditions, which make them an attractive proposition for use as agricultural fungicides. Antimicrobial cyclic peptides are classified according to the types of bonds within the ring structure; homodetic, heterodetic, and complex cyclic peptides, which in turn reflect diverse physicochemical features. Most antimicrobial cyclic peptides affect the integrity of the cell envelope. This is achieved through direct interaction with the cell membrane or disturbance of the cell wall and membrane component biosynthesis such as chitin, glucan, and sphingolipid. These are specific and selective targets providing reliable activity and safety for non-target organisms. Synthetic cyclic peptides produced through combinatorial chemistry offer an alternative approach to develop antimicrobials for agricultural uses. Those synthesized so far have been studied for antibacterial activity, however, the recent advancements in powerful technologies now promise to provide novel antimicrobial cyclic peptides that are yet to be discovered from natural resources.

  16. The evolution of Momordica cyclic peptides.

    Science.gov (United States)

    Mahatmanto, Tunjung; Mylne, Joshua S; Poth, Aaron G; Swedberg, Joakim E; Kaas, Quentin; Schaefer, Hanno; Craik, David J

    2015-02-01

    Cyclic proteins have evolved for millions of years across all kingdoms of life to confer structural stability over their acyclic counterparts while maintaining intrinsic functional properties. Here, we show that cyclic miniproteins (or peptides) from Momordica (Cucurbitaceae) seeds evolved in species that diverged from an African ancestor around 19 Ma. The ability to achieve head-to-tail cyclization of Momordica cyclic peptides appears to have been acquired through a series of mutations in their acyclic precursor coding sequences following recent and independent gene expansion event(s). Evolutionary analysis of Momordica cyclic peptides reveals sites that are under selection, highlighting residues that are presumably constrained for maintaining their function as potent trypsin inhibitors. Molecular dynamics of Momordica cyclic peptides in complex with trypsin reveals site-specific residues involved in target binding. In a broader context, this study provides a basis for selecting Momordica species to further investigate the biosynthesis of the cyclic peptides and for constructing libraries that may be screened against evolutionarily related serine proteases implicated in human diseases. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  17. Variation in mechanical behavior due to different build directions of Titanium6Aluminum4Vanadium fabricated by electron beam additive manufacturing technology

    Science.gov (United States)

    Roy, Lalit

    available. Besides, these values have been compared among themselves in order to understand the effect of anisotropy due to the production nature. Nano-hardness at local points on the specimens' bodies has also been tested for comparison.

  18. Some Structure Properties of the Cyclic Fuzzy Group Family

    Institute of Scientific and Technical Information of China (English)

    Hacl Akta(s); Naim (C)a(g)man

    2005-01-01

    In crisp environment, the notion of cyclic group on a set is well known. We study an extension of this classical notion to the fuzzy sets to define the concept of cyclic fuzzy subgroups. By using these cyclic fuzzy subgroups, we then define a cyclic fuzzy group family and investigate its structure properties.

  19. Degradation and buckling of metal tubes under cyclic bending and external pressure

    Science.gov (United States)

    Corona, Edmundo

    The response and stability of long tubular components under bending and external pressure were investigated. The behavior of the structure under monotonic as well as cyclic bending was examined through combined experimental and analytical efforts. The experiments involved metal seamless tubes with diameter-to-thickness ratios in the range of 17 to 35. Long specimens were tested under combined bending and pressure in a specially developed test facility. Bending-pressure interaction collapse envelopes were first generated for monotonically increasing loading histories. The two loads were found to interact strongly through the ovalization of the cross section and the collapse envelopes to depend on the loading history followed. Cyclic bending under various curvature controlled and moment controlled histories was considered. The factors influencing the rate of accumulation of ovalization and the resulting instabilities were studied parametrically. Buckling under cyclic loads occurred when the ovalization of the tubes reached a critical value approximately equal to the critical value developed under the corresponding monotonically applied loads. The problem was analyzed numerically using kinematics which capture the ovalization of the cross section. The predicted response was found to be very sensitive to the elastic-plastic constitutive models used. This sensitivity was carefully analyzed using state-of-the-art models. In the case of cyclic loading histories, the hardening rules used in such models were found to play a pivotal role in the accuracy of the predictions. The reasons for this sensitivity were studied through a parallel investigation of the behavior of the material under cyclic loads.

  20. Monotonic and cyclic responses of impact polypropylene and continuous glass fiber-reinforced impact polypropylene composites at different strain rates

    KAUST Repository

    Yudhanto, Arief

    2016-03-08

    Impact copolymer polypropylene (IPP), a blend of isotactic polypropylene and ethylene-propylene rubber, and its continuous glass fiber composite form (glass fiber-reinforced impact polypropylene, GFIPP) are promising materials for impact-prone automotive structures. However, basic mechanical properties and corresponding damage of IPP and GFIPP at different rates, which are of keen interest in the material development stage and numerical tool validation, have not been reported. Here, we applied monotonic and cyclic tensile loads to IPP and GFIPP at different strain rates (0.001/s, 0.01/s and 0.1/s) to study the mechanical properties, failure modes and the damage parameters. We used monotonic and cyclic tests to obtain mechanical properties and define damage parameters, respectively. We also used scanning electron microscopy (SEM) images to visualize the failure mode. We found that IPP generally exhibits brittle fracture (with relatively low failure strain of 2.69-3.74%) and viscoelastic-viscoplastic behavior. GFIPP [90]8 is generally insensitive to strain rate due to localized damage initiation mostly in the matrix phase leading to catastrophic transverse failure. In contrast, GFIPP [±45]s is sensitive to the strain rate as indicated by the change in shear modulus, shear strength and failure mode.

  1. Regulation of cyclic photophosphorylation during ferredoxin-mediated electron transport. Effect of DCMU and the NADPH/NADP/sup +/ ratio

    Energy Technology Data Exchange (ETDEWEB)

    Hosler, J.P.; Yocum, C.F.

    1987-04-01

    Addition of ferredoxin to isolated thylakoid membranes reconstitutes electron transport from water to NADP and to O/sub 2/ (the Mehler reaction). This electron flow is coupled to ATP synthesis, and both cyclic and noncyclic electron transport drive photophosphorylation. Under conditions where the NADPH/NADP/sup +/ ratio is varied, as is the amount of ATP synthesis due to cyclic activity is also varied, as is the amount of cyclic activity which is sensitive to antimycin A. Partial inhibition of photosystem II activity with DCMU (which affects reduction of electron carriers of the interphotosystem chain) also affects the level of cyclic activity. The results of these experiments indicate that two modes of cyclic electron transfer activity, which differ in their antimycin A sensitivity, can operate in the thylakoid membrane. Regulation of these activities can occur at the level of ferredoxin and is governed by the NADPH/NADP ratio.

  2. Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products

    Directory of Open Access Journals (Sweden)

    Alexander O. Terent'ev

    2014-01-01

    Full Text Available The present review describes the current status of synthetic five and six-membered cyclic peroxides such as 1,2-dioxolanes, 1,2,4-trioxolanes (ozonides, 1,2-dioxanes, 1,2-dioxenes, 1,2,4-trioxanes, and 1,2,4,5-tetraoxanes. The literature from 2000 onwards is surveyed to provide an update on synthesis of cyclic peroxides. The indicated period of time is, on the whole, characterized by the development of new efficient and scale-up methods for the preparation of these cyclic compounds. It was shown that cyclic peroxides remain unchanged throughout the course of a wide range of fundamental organic reactions. Due to these properties, the molecular structures can be greatly modified to give peroxide ring-retaining products. The chemistry of cyclic peroxides has attracted considerable attention, because these compounds are used in medicine for the design of antimalarial, antihelminthic, and antitumor agents.

  3. Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products.

    Science.gov (United States)

    Terent'ev, Alexander O; Borisov, Dmitry A; Vil', Vera A; Dembitsky, Valery M

    2014-01-08

    The present review describes the current status of synthetic five and six-membered cyclic peroxides such as 1,2-dioxolanes, 1,2,4-trioxolanes (ozonides), 1,2-dioxanes, 1,2-dioxenes, 1,2,4-trioxanes, and 1,2,4,5-tetraoxanes. The literature from 2000 onwards is surveyed to provide an update on synthesis of cyclic peroxides. The indicated period of time is, on the whole, characterized by the development of new efficient and scale-up methods for the preparation of these cyclic compounds. It was shown that cyclic peroxides remain unchanged throughout the course of a wide range of fundamental organic reactions. Due to these properties, the molecular structures can be greatly modified to give peroxide ring-retaining products. The chemistry of cyclic peroxides has attracted considerable attention, because these compounds are used in medicine for the design of antimalarial, antihelminthic, and antitumor agents.

  4. Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products

    Science.gov (United States)

    Borisov, Dmitry A; Vil’, Vera A; Dembitsky, Valery M

    2014-01-01

    Summary The present review describes the current status of synthetic five and six-membered cyclic peroxides such as 1,2-dioxolanes, 1,2,4-trioxolanes (ozonides), 1,2-dioxanes, 1,2-dioxenes, 1,2,4-trioxanes, and 1,2,4,5-tetraoxanes. The literature from 2000 onwards is surveyed to provide an update on synthesis of cyclic peroxides. The indicated period of time is, on the whole, characterized by the development of new efficient and scale-up methods for the preparation of these cyclic compounds. It was shown that cyclic peroxides remain unchanged throughout the course of a wide range of fundamental organic reactions. Due to these properties, the molecular structures can be greatly modified to give peroxide ring-retaining products. The chemistry of cyclic peroxides has attracted considerable attention, because these compounds are used in medicine for the design of antimalarial, antihelminthic, and antitumor agents. PMID:24454562

  5. Fatigue Damage Analysis by Use of Cyclic Strain Approach

    DEFF Research Database (Denmark)

    Andersen, Michael Rye

    1996-01-01

    A number of cracks were reported in a bulk carrier (approx. 300m long) after 23 years of trade. The ship was still in good condition, no significant corrosion was found by inspection. The trade routes of the vessel were in the North Atlantic, usually one voyage in fully loaded condition followed...... of the deck. The initiation of the cracks was probably due to fatigue damage. In this paper the cracks will be investigated using the cyclic strain approach, and the obtained results will be compared with fatigue lives estimated by the S-N approach....

  6. Cyclic Benzimidazole Derivatives and Their Antitumor Activity

    Directory of Open Access Journals (Sweden)

    Karminski-Zamola, G.

    2008-06-01

    Full Text Available Over the past years benzimidazole derivatives are one of the most extensively studied classes of heterocyclic compounds, and have received much attention from synthetic organic as well as medicinal chemists, because of their well known biological activities and their applications in several areas as materials in electronics, in electrochemistry as anticorrosive agents, as polymers or optical materials and fluorescent tags in DNA sequencing. The structure of vitamin B12, as an example, contains a benzimidazole group. Compounds containing benzimidazole nuclei show anticancer, antineoplastic, antiinfective, antibacterial, antifungal and many others activities. Due to the structural similarity of benzimidazole nuclei with some naturally occurring compounds such as purine, they can easily interact with biomolecules of the living systems. The introduction of an additional substituent on the benzimidazole nuclei has been increasing attention in the expectation that such changes could potentially affect the interaction of the molecules with biological targets. Fused cyclic benzimidazole derivatives, as benzimidazo[1,2-a]quinolines,benzimidazo[1,2-c]quinazolines, benzimidazo[2,1-b]isoquinolines and many others, have also interesting biological activities and most of them are very good anticancer agents.DNA is the molecular target of many anticancer drugs in clinical use and development. Compounds which can bind to DNA with intercalative or non-intercalative mechanism play a major role in biological processes such as gene transcription or DNA replication. Benzoannulated benzimidazole analogues contain a planar chromophore and have the ability to become inserted between adjacent base pairs of DNA double helix. Intercalators are recognized as one of the most important classes of anticancer agents. So an understanding of the drug-DNA interactions is a promising approach to developing novel reagents and plays a key role in pharmacology today.

  7. 高血压患者的患病行为及其影响因素%Analysis on behaviors due to diseases in the patients having hypertension and the factors affecting the behaviors

    Institute of Scientific and Technical Information of China (English)

    谈菊华; 鲁萍

    2009-01-01

    Objective To approach hypertensive patients' understandings of their own diseases, daily behaviors responding to their complaints and the factors affecting their abnormal behaviors. Methods A specially-designed questionnaire survey was adopted and total 98 cases of all internal-patients suffering from hypertension were surveyed. Results The percentage of patients involving in the survey with abnormal psychological orientations is 38.8%. That of patients with abnormal disease confirmation factors is 46.9%. And that of patients with abnormal hypochondria index is 43.9%. The main factors affecting patients' behaviors are Age, Educational Background and Working Stress felt by themselves. Conclusions Nurses should attach more importance to the cognitive trainings of hypertension patients, get along with patients who have abnormal disease response symptoms and especially, pay more attention to Health Education and Psychological Nursing to patients who are seniors, higher-educated or whoever suffering working stress.%目的 了解高血压患者对自身疾病的认知、行为现状及异常患病行为的影响因素.方法 采用"患病行为问卷"对98例高血压住院患者进行问卷调查.结果 心理取向因子异常者占38.8%,疾病确信因子异常者占46.9%,疑病指数异常者占43.9%;影响患者行为的主要影响因素有年龄、文化程度和自觉工作紧张度.结论 护士应重视高血压患者的患病认知教育,尤其要做好年龄较大、文化程度较高、自觉工作紧张患者的健康教育和心理护理.

  8. Laboratory testing of cyclic laterally loaded pile in cohesionless soil. [MONOPILES

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Mette; Kirk Wolf, T. [COWI, Kgs. Lyngby (Denmark); Lange Rasmussen, K. [Niras, Aalborg (Denmark); Ravn Roesen, H.; Ibsen, L.B. [Aalborg Univ.. Dept. of Civil Engineering, Aalborg (Denmark)

    2013-06-15

    Offshore wind turbines are placed in a rough environment, subjected to variable lateral loads, mostly from wind and waves. A long-term lateral loading may create rotation (tilt) of the pile by change in the soil-pile system which is critical in the serviceability limit state. The accumulated rotation due to long-term lateral loading is therefore a current issue of interest as today's design guidances have little knowledge in this area. The cost of large-scale testing is extensive which make small-scale testing desirable as a tool for describing the behaviour of a soil-pile system subjected to lateral load. In this paper small-scale testing of a pile subjected to cyclic, lateral loading is treated in order to investigate the effect of cyclic loading. The test pile has a diameter of 100 mm and is 600 mm high, making the slenderness ratio 6, which resembles the ratio of offshore wind turbines today. The test pile is placed in saturated dense sand. A monotonic test is conducted to define the ultimate lateral capacity. Afterwards a cyclic test is conducted to investigate the accumulation of rotation when the pile is subjected to cyclic lateral load. Force and displacement during both tests are recorded to determine the deformation of the pile. Comparing the responses of the monotonic and the cyclic test, the cyclic test shows a stiffer response. During the cyclic test, the rotation of the pile accumulates with decreasing rotation increments. However, no stabilised situation occurs. The measured data is compared to theories on degradation, agreeing that the accumulated rotation as an estimate can be express by both a logarithmic and exponential expression. Comparing the results from the cyclic test with results from other recent small-scale tests shows agreement in the accumulation of rotation with decreasing rotation increments with no stabilising situation. (Author)

  9. Isochronous relaxation curves for type 304 stainless steel after monotonic and cyclic strain

    Energy Technology Data Exchange (ETDEWEB)

    Swindeman, R.W.

    1978-01-01

    Relaxation tests to 100 hr were performed on type 304 stainless steel in the temperature range 480 to 650/sup 0/C and were used to develop isochronous relaxation curves. Behavior after monotonic and cyclic strain was compared. Relaxation differed only slightly as a consequence of the type of previous strain, provided that plastic flow preceded the relaxation period. We observed that the short-time relaxation behavior did not manifest strong heat-to-heat variation in creep strength.

  10. Regulation of cyclic GMP, cyclic amp and lactate dehydrogenase by putative neutrotransmitters in the C6 rat glioma cell line

    Energy Technology Data Exchange (ETDEWEB)

    Bottenstein, J.E.; de Vellis, J.

    1977-01-01

    In C6 cells norepinephrine and dopamine caused transient increases in cyclic GMP and cyclic AMP, as well as an induction of lactate dehydrogenase. All of these responses were blocked by 1-propranolol, suggesting mediation by a ..beta..-receptor. Phentolamine potentiated the NE-increased cAMP levels by 5-fold when NE was used at suboptimal doses, suggesting the presence of ..cap alpha..-adrenergic receptors in C6 cells. Carbamylcholine decreased the levels of both cyclic nucleotides, with hexamethonium partially reversing the effect on cyclic GMP. Dibutyryl-cyclic GMP or carbamylcholine reduced catecholamine-induced cyclic AMP levels. Serotonin increased cyclic GMP levels 60% and decreased cyclic AMP levels 36%. Calcium- and magnesium-free media inhibited the norepinephrine-induced levels of cyclic GMP and cyclic AMP respectively.

  11. Regulation of cyclic GMP, cyclic AMP and lactate dehydrogenase by putative neurotransmitters in the C6 rat glioma cell line

    Energy Technology Data Exchange (ETDEWEB)

    Bottenstein, J.E.; de Vellis, J.

    1978-01-01

    In C6 cells norepinephrine and dopamine caused transient increases in cyclic GMP and cyclic AMP, as well as an induction of lactate dehydrogenase. All of these responses were blocked by l-propranolol, suggesting mediation by a ..beta..-receptor. Phentolamine potentiated the NE-increased cAMP levels by 5-fold when NE was used at suboptimal doses, suggesting the presence of ..cap alpha..-adrenergic receptors in C6 cells. Carbamylcholine decreased the levels of both cyclic nucleotides, with hexamethonium partially reversing the effect on cyclic GMP. Dibutyryl-cyclic GMP or carbamylcholine reduced catecholamine-induced cyclic AMP levels. Serotonin increased cyclic GMP levels 60% and decreased cyclic AMP levels 36%. Calcium- and magnesium-free media inhibited the norepinephrine-induced levels of cyclic GMP and cyclic AMP respectively.

  12. Cyclic transformation of orbital angular momentum modes

    CERN Document Server

    Schlederer, Florian; Fickler, Robert; Malik, Mehul; Zeilinger, Anton

    2015-01-01

    The spatial modes of photons are one realization of a QuDit, a quantum system that is described in a D-dimensional Hilbert space. In order to perform quantum information tasks with QuDits, a general class of D-dimensional unitary transformations is needed. Among these, cyclic transformations are an important special case required in many high-dimensional quantum communication protocols. In this paper, we experimentally demonstrate a cyclic transformation in the high-dimensional space of photonic orbital angular momentum (OAM). Using simple linear optical components, we show a successful four-fold cyclic transformation of OAM modes. Interestingly, our experimental setup was found by a computer algorithm. In addition to the four-cyclic transformation, the algorithm also found extensions to higher-dimensional cycles in a hybrid space of OAM and polarization. Besides being useful for quantum cryptography with QuDits, cyclic transformations are key for the experimental production of high-dimensional maximally enta...

  13. Cyclic transformation of orbital angular momentum modes

    Science.gov (United States)

    Schlederer, Florian; Krenn, Mario; Fickler, Robert; Malik, Mehul; Zeilinger, Anton

    2016-04-01

    The spatial modes of photons are one realization of a QuDit, a quantum system that is described in a D-dimensional Hilbert space. In order to perform quantum information tasks with QuDits, a general class of D-dimensional unitary transformations is needed. Among these, cyclic transformations are an important special case required in many high-dimensional quantum communication protocols. In this paper, we experimentally demonstrate a cyclic transformation in the high-dimensional space of photonic orbital angular momentum (OAM). Using simple linear optical components, we show a successful four-fold cyclic transformation of OAM modes. Interestingly, our experimental setup was found by a computer algorithm. In addition to the four-cyclic transformation, the algorithm also found extensions to higher-dimensional cycles in a hybrid space of OAM and polarization. Besides being useful for quantum cryptography with QuDits, cyclic transformations are key for the experimental production of high-dimensional maximally entangled Bell-states.

  14. Cyclical synchronization in the EMU along the financial crisis: An interpretation of the conflicting signals

    Directory of Open Access Journals (Sweden)

    Jose Ramon Cancelo

    2012-06-01

    Full Text Available We analyze how cyclical synchronization in the EMU evolved since the onset of the current financial crisis. The standard measures of cyclical correlation suggest that while the cycle of the euro area became more aligned with the cycles of other developed economies, the EMU itself apparently entered into a phase of cyclical divergence. We show that as a matter of fact the bulk of the member states remained closely aligned, and the seeming decline in synchronization is due to a few countries decoupling from the euro area. Next we present empirical evidence that the foundations that explain the evolution of the national cycles against the EMU aggregate through the crisis were already latent in 2007. Greece and Ireland deviate from the general pattern, the former because of its loose fiscal policy all along the period 2000-2007, and the latter due to the flexibility of its labor market.

  15. Nonlinear analytical solution for one-dimensional consolidation of soft soil under cyclic loading

    Institute of Scientific and Technical Information of China (English)

    XIE Kang-he; QI Tian; DONG Ya-qin

    2006-01-01

    This paper presents an analytical solution for one-dimensional consolidation of soft soil under some common types of cyclic loading such as trapezoidal cyclic loading, based on the assumptions proposed by Davis and Raymond (1965) that the decrease in permeability is proportional to the decrease in compressibility during the consolidation process of the soil and that the distribution of initial effective stress is constant with depth. It is verified by the existing analytical solutions in special cases. Using the solution obtained, some diagrams are prepared and the relevant consolidation behavior is investigated.

  16. Detection of gamma-irradiation effect on DNA and protein using magnetic sensor and cyclic voltammetry.

    Science.gov (United States)

    Park, Duck-Gun; Song, Hoon; Kishore, M B; Vértesy, G; Lee, Duk-Hyun

    2013-11-01

    In this study, a magnetic sensor utilizing Planar Hall Resistance (PHR) and cyclic Voltammetry (CV) for detecting the radiation effect was fabricated. Specifically, we applied in parallel a PHR sensor and CV device to monitor the irradiation effect on DNA and protein respectively. Through parallel measurements, we demonstrated that the PHR sensor and CV are sensitive enough to measure irradiation effect. The PHR voltage decreased by magnetic nanobead labeled DNA was slightly recovered after gamma ray irradiation. The behavior of cdk inhibitor protein p21 having a sandwich structure of Au/protein G/Ab/Ag/Ab was checked by monitoring the cyclic Voltammetry signal in analyzing the gamma ray irradiation effect.

  17. Generalized Phenomenological Cyclic Stress-Strain-Strength Characterization of Granular Media.

    Science.gov (United States)

    1984-09-02

    following special form of the general hypoelastic equation to model the behavior of granular media: dij = [a0 dem + a3 "pq d pq] 6ij + 1 dcij + C 2 dem...Phenomitno ogical I C.yclic Stress-Strain-Strength Characterization f Granular M~dia !RSO%.hL APT’.OR(S) M._McVay,_D._Seereeram,_P.__Linton andD... Granular Medi a, Vollow Cylinder. Cyclic Triaxial Test, Plasticity, Prediction Expanding Cavity LClic CTC rests ISTAAC? fCoom w mz_’-. ,f_.V,,A6’V "d

  18. Evaluation of homogeneous electrocatalysts by cyclic voltammetry.

    Science.gov (United States)

    Rountree, Eric S; McCarthy, Brian D; Eisenhart, Thomas T; Dempsey, Jillian L

    2014-10-06

    The pursuit of solar fuels has motivated extensive research on molecular electrocatalysts capable of evolving hydrogen from protic solutions, reducing CO2, and oxidizing water. Determining accurate figures of merit for these catalysts requires the careful and appropriate application of electroanalytical techniques. This Viewpoint first briefly presents the fundamentals of cyclic voltammetry and highlights practical experimental considerations before focusing on the application of cyclic voltammetry for the characterization of electrocatalysts. Key metrics for comparing catalysts, including the overpotential (η), potential for catalysis (E(cat)), observed rate constant (k(obs)), and potential-dependent turnover frequency, are discussed. The cyclic voltammetric responses for a general electrocatalytic one-electron reduction of a substrate are presented along with methods to extract figures of merit from these data. The extension of this analysis to more complex electrocatalytic schemes, such as those responsible for H2 evolution and CO2 reduction, is then discussed.

  19. Cyclic distillation technology - A mini-review

    DEFF Research Database (Denmark)

    Bîldea, Costin Sorin; Pătruţ, Cătălin; Jørgensen, Sten Bay;

    2016-01-01

    Process intensification in distillation systems has received much attention during the past decades, with the aim of increasing both energy and separation efficiency. Various techniques, such as internal heat-integrated distillation, membrane distillation, rotating packed bed, dividing-wall columns...... and reactive distillation were studied and reported in literature. All these techniques employ the conventional continuous counter-current contact of vapor and liquid phases. Cyclic distillation technology is based on an alternative operating mode using separate phase movement which leads to key practical...... advantages in both chemical and biochemical processes. This article provides a mini-review of cyclic distillation technology. The topics covered include the working principle, design and control methods, main benefits and limitations as well as current industrial applications. Cyclic distillation can...

  20. A Continuum Damage Mechanics Model for the Static and Cyclic Fatigue of Cellular Composites

    Science.gov (United States)

    Huber, Otto

    2017-01-01

    The fatigue behavior of a cellular composite with an epoxy matrix and glass foam granules is analyzed and modeled by means of continuum damage mechanics. The investigated cellular composite is a particular type of composite foam, and is very similar to syntactic foams. In contrast to conventional syntactic foams constituted by hollow spherical particles (balloons), cellular glass, mineral, or metal place holders are combined with the matrix material (metal or polymer) in the case of cellular composites. A microstructural investigation of the damage behavior is performed using scanning electron microscopy. For the modeling of the fatigue behavior, the damage is separated into pure static and pure cyclic damage and described in terms of the stiffness loss of the material using damage models for cyclic and creep damage. Both models incorporate nonlinear accumulation and interaction of damage. A cycle jumping procedure is developed, which allows for a fast and accurate calculation of the damage evolution for constant load frequencies. The damage model is applied to examine the mean stress effect for cyclic fatigue and to investigate the frequency effect and the influence of the signal form in the case of static and cyclic damage interaction. The calculated lifetimes are in very good agreement with experimental results. PMID:28809806

  1. Effect of cyclic aeration on fouling in submerged membrane bioreactor for wastewater treatment.

    Science.gov (United States)

    Wu, Jun; He, Chengda

    2012-07-01

    Due to the inefficiency of aeration measures in preventing fouling by soluble and colloidal particles. The effect of alternating high/low cyclic aeration mode on the membrane fouling in the submerged membrane bioreactor was studied by comparing to fouling in a constant aeration mode. Results indicated a higher overall fouling rate in the cyclic aeration mode than in the constant aeration. However, a higher percentage of reversible fouling was observed for the cyclic aeration mode. The membrane permeability can be more easily recovered from physical cleaning such as backwashing in the cyclic aeration mode. The activated sludge floc size distribution analysis revealed a floc destruction and re-flocculation processes caused by the alternating high/low aeration. The short high aeration period could prevent the destruction of strong strength bonds within activated sludge flocs. Therefore, less soluble and colloidal material was observed in the supernatant due to the preservation of the strong strength bonds. The weak strength bonds damaged in the high aeration period could be recovered in the re-flocculation process in the low aeration period. The floc destruction and re-flocculation processes were suggested to be the main reason for the low irreversible fouling in the cyclic aeration mode.

  2. Kenaf Fibre Reinforced Polypropylene Composites: Effect of Cyclic Immersion on Tensile Properties

    Directory of Open Access Journals (Sweden)

    W. H. Haniffah

    2015-01-01

    Full Text Available This research studied the degradation of tensile properties of kenaf fibre reinforced polypropylene composites due to cyclic immersion into two different solutions, as well as comparison of the developed composites’ tensile properties under continuous and cyclic immersion. Composites with 40% and 60% fibre loadings were immersed in tap water and bleach for 4 cycles. Each cycle consisted of 3 days of immersion and 4 days of conditioning in room temperature (28°C and 55% humidity. The tensile strength and modulus of composites were affected by fibre composition, type of liquid of immersion, and number of cycles. The number of immersion cycles and conditioning caused degradation to tensile strength and modulus of kenaf fibre reinforced polypropylene composites. Continuous and cyclic immersion in bleach caused tensile strength of the composites to differ significantly whereas, for tensile modulus, the difference was insignificant in any immersion and fibre loadings. However, continuous immersion in the bleach reduced the tensile strength of composites more compared to cyclic immersion. These preliminary results suggest further evaluation of the suitability of kenaf fibre reinforced polypropylene composites for potential bathroom application where the composites will be exposed to water/liquid in cyclic manner due to discontinuous usage of bathroom.

  3. Monetary Policy, Debt and the Cyclical Behavior of Inventories

    Directory of Open Access Journals (Sweden)

    Abdul Ghafar Ismail

    2007-01-01

    Full Text Available An earlier study on the determinants of inventories investment has been proposed by Lovel (1961. However, the study fails to mention the effects of financial variables. The puzzle prevails on account of imperfect capital markets. This implies that interest rate generally affects inventory investment indirectly through the debt channel. For instance, in the period of tight monetary policy, increasing interest rates have a negative impact on the present value of firms’ collateralizable net worth. In addition, they also weaken firms’ balance sheets as interest expenses also rise up. In imperfect capital markets, this fact indicates an increase in the amount of external financing that firms need, a rise in the premium on external financing that they face, and a reduction in their accumulation of assets, their spending and their production. Given the low adjustment cost that characterizes firms, it will be inventories that firms will initially reduce. Therefore, this paper is contributes to the issue of monetary policy transmission in Malaysia. Our specific attention is limited to the channel of monetary policy on a firm’s inventory. Using micro data, we try to take into account the relevance of the firm’s balance sheet conditions in the transmission of monetary policy.

  4. Cyclic Polymer with Alternating Monomer Sequence.

    Science.gov (United States)

    Zhu, Wen; Li, Zi; Zhao, Youliang; Zhang, Ke

    2015-11-01

    Cyclic polymers with alternating monomer sequence are synthesized for the first time based on the ring-closure strategy. Well-defined telechelic alternating polymers are synthesized by reversible addition-fragmentation chain transfer polymerization by copolymerizing the electron acceptor monomer of N-benzylmaleimide and donor monomer of styrene with a feed ratio of 1 between them. The corresponding cyclic alternating polymers are then produced by the UV-induced Diels-Alder click reaction to ring-close the linear alternating polymer precursors under highly diluted reaction solution.

  5. On cyclic associative Abel-Grassman groupoids

    OpenAIRE

    Iqbal, Muhammad; Ahmad, Imtiaz; Shah, Muhammad; Ali, Muhammad Irfan

    2015-01-01

    A new subclass of AG-groupoids, so called, cyclic associative Abel-Grassman groupoids or CA-AG-groupoid is studied. These have been enumerated up to order $6$. A test for the verification of cyclic associativity for an arbitrary AG-groupoid has been introduced. Various properties of CA-AG-groupoids have been studied. Relationship among CA-AG-groupoids and other subclasses of AG-groupoids is investigated. It is shown that the subclass of CA-AG-groupoid is different from that of the AG{*}-group...

  6. Undrained Cyclic Behaviour of Dense Frederikshavn Sand

    DEFF Research Database (Denmark)

    Nielsen, Søren Kjær; Ibsen, Lars Bo; Sørensen, Kris Wessel

    2013-01-01

    A modified contour diagram is created for the Frederikshavn Sand in the undrained case for a relative density of ID = 80 %. It can be used to estimate the number of cycles to failure for a given combination of pore pressure, average and cyclic load ratio. The diagram is based on a series of undra......A modified contour diagram is created for the Frederikshavn Sand in the undrained case for a relative density of ID = 80 %. It can be used to estimate the number of cycles to failure for a given combination of pore pressure, average and cyclic load ratio. The diagram is based on a series...

  7. Cyclic Entropy: An Alternative to Inflationary Cosmology

    CERN Document Server

    Frampton, Paul Howard

    2015-01-01

    We address how to construct an infinitely cyclic universe model. A major consideration is to make the entropy cyclic which requires the entropy to be reset to zero in each cycle expansion to turnaround, to contraction, to bounce, etc. Here we reset entropy at the turnaround by selecting the visible universe from the multiverse which is generated by the accelerated expansion. In the model, the observed homogeneity is explained by the low entropy at the bounce, The observed flatness arises from the contraction together with the reduction in size between the expanding and contracting universe. The present flatness is predicted to be very precise.

  8. Ultrafast cyclic voltammetry with asymmetrical potential scan

    Institute of Scientific and Technical Information of China (English)

    Zhi Yong Guo; Xiang Qin Lin

    2008-01-01

    Based on the perfect ohmic drop compensation by online electronic positive feedback, ultrafast cyclic voltammetry withasymmetrical potential scan is achieved for the first time, with the reduction of anthracene acting as the test system. Compared withthe traditional cyclic voltammetry utilizing symmetrical triangular waveform as the excitation one, the new method allows a simplerapproach to mechanistic analysis of ultrafast chemical reactions coupled with a charge transfer. And perhaps more important, it alsoprovides a way to eliminate the interference of the adsorbed product in dynamic monitoring.

  9. Severe congenital cyclic neutropenia: A case report

    Science.gov (United States)

    Patil, Vidyavathi H; Hugar, Shivayogi M; Balikai, Girish; Patil, Sudha

    2016-01-01

    Congenital cyclic neutropenia syndrome is a constitutional genetic disorder which is characterized by very low number of neutrophils (neutropenia). Patients suffering from this disorder clinically present with neutropenia at early age, history of recurrent fever, ulcerations in the oral cavity, gingivitis, and other recurrent infections. This paper describes a case report of a child with recurrent mouth ulcers, fever, and later diagnosed with severe congenital cyclic neutropenia. This also emphasizes the importance of identification of rare causes of immunosuppressive conditions in children presenting with recurrent oral ulcers and poor dental hygiene, to prevent long-term complications of oral cavity and also morbidity and mortality secondary to neutropenic sepsis. PMID:27857902

  10. Infrared thermographic analysis of shape memory polymer during cyclic loading

    Science.gov (United States)

    Staszczak, Maria; Pieczyska, Elżbieta A.; Maj, Michał; Kukla, Dominik; Tobushi, Hisaaki

    2016-12-01

    In this paper we present the effects of thermomechanical couplings occurring in polyurethane shape memory polymer subjected to cyclic tensile loadings conducted at various strain rates. Stress-strain characteristics were elaborated using a quasistatic testing machine, whereas the specimen temperature changes accompanying the deformation process were obtained with an infrared camera. We demonstrate a tight correlation between the mechanical and thermal results within the initial loading stage. The polymer thermomechanical behaviour in four subsequent loading-unloading cycles and the influence of the strain rate on the stress and the related temperature changes were also examined. In the range of elastic deformation the specimen temperature drops below the initial level due to thermoelastic effect whereas at the higher strains the temperature always increased, due to the dissipative deformation mechanisms. The difference in the characteristics of the specimen temperature has been applied to determine a limit of the polymer reversible deformation and analyzed for various strain rates. It was shown that at the higher strain rates higher values of the stress and temperature changes are obtained, which are related to higher values of the polymer yield points. During the cyclic loading a significant difference between the first and the second cycle was observed. The subsequent loading-unloading cycles demonstrated similar sharply shaped stress and temperature profiles and gradually decrease in values.

  11. Mechanical behaviors of the joint between steel reinforced concrete L-shaped column and concrete beam frame under low-cyclic reversed loading%型钢混凝土L形柱—混凝土梁节点的受力性能

    Institute of Scientific and Technical Information of China (English)

    陈宗平; 王妮; 薛建阳; 胡秀杰

    2011-01-01

    为了研究型钢混凝土(SRC)L形柱—混凝土梁框架节点的受力性能,设计了4个试件进行低周反复加载试验,揭示了其受力破坏机理;获取了节点受力全过程的荷载—位移滞回曲线和荷载—应变滞回曲线,分析了其变形能力和能量耗散能力.结果表明:反复荷载作用下SRC异形柱框架角节点的抗震性能良好,荷载—位移滞回曲线的滞回环饱满、对称,其抗震承载能力高,综合抗震指标明显优于钢筋混凝土异形柱框架角节点的.研究可为SRC异形柱框架角节点受力机理的分析和承载力计算方法的建立提供试验依据.%In order to reveal the mechanical behavior of joints between steel reinforced concrete (SRC) L-shaped column and concrete beam frame, 4 specimens were designed for low-cyclic reversed loading test. Failure mechanism of the joints is revealed. The hysteretic curves of load-displacement relation and load-strain relation of the joints were obtained, and deformability and dissipation capacity of the joints were analyzed. The results indicate that the seismic behavior of the corner joints in steel reinforced concrete special-shaped column frame is good. The load-displacement hysteretic curves of the specimens are symmetric and plump, and the seismic index of the joints are higher than those of the joints in RC special-shaped column frame. This study can be helpful for the analysis of mechanism and the establishment of calculation method of the corner joints in steel reinforced concrete special-shaped column frame.

  12. Ratcheting induced cyclic softening behaviour of 42CrMo4 steel

    Science.gov (United States)

    Kreethi, R.; Mondal, A. K.; Dutta, K.

    2015-02-01

    Ratcheting is an important field of fatigue deformation which happens under stress controlled cyclic loading of materials. The aim of this investigation is to study the uniaxial ratcheting behavior of 42CrMo4 steel in annealed condition, under various applied stresses. In view of this, stress controlled fatigue tests were carried out at room temperature up to 200 cycles using a servo-hydraulic universal testing machine. The results indicate that accumulation of ratcheting strain increases monotonically with increasing maximum applied stress however; the rate of strain accumulation attains a saturation plateau after few cycles. The investigated steel shows cyclic softening behaviour under the applied stress conditions. The nature of strain accumulation and cyclic softening has been discussed in terms of dislocation distribution and plastic damage incurred in the material.

  13. Effect of deformation frequency on temperature and stress oscillations in cyclic phase transition of NiTi shape memory alloy

    Science.gov (United States)

    Yin, Hao; He, Yongjun; Sun, Qingping

    2014-07-01

    Distinctive temperature and stress oscillations can be observed in superelastic shape memory alloys (SMAs) when they subject to displacement-controlled cyclic phase transition. In this paper, we examine the effect of the deformation frequency on the thermal and mechanical responses of the polycrystalline superelastic NiTi rods under stress-induced cyclic phase transition. By synchronized measurement of the evolutions in overall temperature and stress-strain curve over the frequency range of 0.0004-1 Hz (corresponding average strain rate range of 4.8×10-5/s-1.2×10-1/s) in stagnant air, it was found that both the temperature evolution and the stress-strain curve vary significantly with the frequency and the number of cycles. For each frequency, steady-state cyclic thermal and mechanical responses of the specimen were reached after a transient stage, exhibiting stabilization. In the steady-state, the average temperature oscillated around a mean temperature plateau which increased monotonically with the frequency and rose rapidly in the high frequency range due to the rapid accumulation of hysteresis heat. The oscillation was mainly caused by the release and absorption of latent heat and increased with the frequency, eventually reaching a saturation value. The variations in the stress responses followed similar frequency dependence as the temperature. The steady-state stress-strain hysteresis loop area, as a measure of the material's damping capacity, first increased then decreased with the frequency in a non-monotonic manner. The experimental data were analyzed and discussed based on the simplified lumped heat transfer analysis and the Clausius-Clapeyron relationship, incorporating the inherent thermomechanical coupling in the material's response. We found that, for given material's properties and specimen geometries, all such frequency-dependent variations in temperature, stress and damping capacity were essentially determined by the competition between the time

  14. Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.

    Science.gov (United States)

    Lorenz, Robin; Moon, Eui-Whan; Kim, Jeong Joo; Schmidt, Sven H; Sankaran, Banumathi; Pavlidis, Ioannis V; Kim, Choel; Herberg, Friedrich W

    2017-07-06

    Cyclic AMP and cyclic GMP are ubiquitous second messengers that regulate the activity of effector proteins in all forms of life. The main effector proteins, the 3',5'-cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) and the 3',5'-cyclic guanosine monophosphate (cGMP)-dependent protein kinase (PKG), are preferentially activated by cAMP and cGMP, respectively. However, the molecular basis of this cyclic nucleotide selectivity is still not fully understood. Analysis of isolated cyclic nucleotide-binding (CNB) domains of PKA regulatory subunit type Iα (RIα) reveals that the C-terminal CNB-B has a higher cAMP affinity and selectivity than the N-terminal CNB-A. Here, we show that introducing cGMP-specific residues using site-directed mutagenesis reduces the selectivity of CNB-B, while the combination of two mutations (G316R/A336T) results in a cGMP-selective binding domain. Furthermore, introducing the corresponding mutations (T192R/A212T) into the PKA RIα CNB-A turns this domain into a highly cGMP-selective domain, underlining the importance of these contacts for achieving cGMP specificity. Binding data with the generic purine nucleotide 3',5'-cyclic inosine monophosphate (cIMP) reveal that introduced arginine residues interact with the position 6 oxygen of the nucleobase. Co-crystal structures of an isolated CNB-B G316R/A336T double mutant with either cAMP or cGMP reveal that the introduced threonine and arginine residues maintain their conserved contacts as seen in PKG I CNB-B. These results improve our understanding of cyclic nucleotide binding and the molecular basis of cyclic nucleotide specificity. © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.

  15. Theoretical design of the cyclic lipopeptide nanotube as a molecular channel in the lipid bilayer, molecular dynamics and quantum mechanics approach.

    Science.gov (United States)

    Khavani, Mohammad; Izadyar, Mohammad; Housaindokht, Mohammad Reza

    2015-10-14

    In this article, cyclic peptides (CP) with lipid substituents were theoretically designed. The dynamical behavior of the CP dimers and the cyclic peptide nanotube (CPNT) without lipid substituents in the solution (water and chloroform) during the 50 ns molecular dynamic (MD) simulations has been investigated. As a result, the CP dimers and CPNT in a non-polar solvent are more stable than in a polar solvent and CPNT is a good container for non-polar small molecules such as chloroform. The effect of the lipid substituents on the CP dimers and CPNT has been investigated in the next stage of our studies. Accordingly, these substituents increase the stability of the CP dimers and CPNT, significantly, in polar solvents. MM-PBSA and MM-GBSA calculations confirm that substitution has an important effect on the stability of the CP dimers and CPNT. Finally, the dynamical behavior of CPNT with lipid substituents in a fully hydrated DMPC bilayer shows the high ability of this structure for molecule transmission across the lipid membrane. This structure is stable enough to be used as a molecular channel. DFT calculations on the CP dimers in the gas phase, water and chloroform, indicate that H-bond formation is the driving force for dimerization. CP dimers are more stable in the gas phase in comparison to in solution. HOMO-LUMO orbital analysis indicates that the interaction of the CP units in the dimer structures is due to the molecular orbital interactions between the NH and CO groups.

  16. The coefficient of cyclic variation: a novel statistic to measure the magnitude of cyclic variation.

    Science.gov (United States)

    Fulford, Anthony Jc

    2014-01-01

    PERIODIC OR CYCLIC DATA OF KNOWN PERIODICITY ARE FREQUENTLY ENCOUNTERED IN EPIDEMIOLOGICAL AND BIOMEDICAL RESEARCH: for instance, seasonality provides a useful experiment of nature while diurnal rhythms play an important role in endocrine secretion. There is, however, little consensus on how to analysis these data and less still on how to measure association or effect size for the often complex patterns seen. A simple statistic, readily derived from Fourier regression models, provides a readily-understood measure cyclic variation in a wide variety of situations. The coefficient of cyclic variation or similar statistics derived from the variance of a Fourier series could provide a universal means of summarising the magnitude of periodic variation.

  17. Rh(0)/Rh(iii) core-shell nanoparticles as heterogeneous catalysts for cyclic carbonate synthesis.

    Science.gov (United States)

    Jung, Younjae; Shin, Taeil; Kim, Kiseong; Byun, Hyeeun; Cho, Sung June; Kim, Hyunwoo; Song, Hyunjoon

    2016-12-22

    Rh(0)/Rh(iii) core-shell nanoparticles were prepared by surface oxidation of Rh nanoparticles with N-bromosuccinimide. They were employed as heterogeneous catalysts for cyclic carbonate synthesis from propylene oxide and CO2, and exhibited high activity and excellent recyclability due to Lewis acidic Rh(iii) species on the shells.

  18. Cyclic olefin polymers: emerging materials for lab-on-a-chip applications

    DEFF Research Database (Denmark)

    Nunes, Pedro; Ohlsson, Pelle; Sala, Olga Ordeig

    2010-01-01

    Cyclic olefin polymers (COPs) are increasingly popular as substrate material for microfluidics. This is due to their promising properties, such as high chemical resistance, low water absorption, good optical transparency in the near UV range and ease of fabrication. COPs are commercially availabl...

  19. The Formation of Crystal Defects in a Fe-Mn-Si Alloy Under Cyclic Martensitic Transformations.

    Science.gov (United States)

    Bondar, Vladimir I; Danilchenko, Vitaliy E; Iakovlev, Viktor E

    2016-12-01

    Formation of crystalline defects due to cyclic martensitic transformations (CMT) in the iron-manganese Fe-18 wt.% Mn-2 wt.% Si alloy was investigated using X-ray diffractometry. Conditions for accumulation of fragment sub-boundaries with low-angle misorientations and chaotic stacking faults in crystal lattice of austenite and ε-martensite were analyzed.

  20. Special subvarieties arising from families of cyclic covers of the projective line

    CERN Document Server

    Moonen, Ben

    2010-01-01

    We consider families of cyclic covers of the projective line, where we fix the covering group and the local monodromies and we vary the branch points. We prove that there are precisely twenty such families that give rise to a special subvariety in the moduli space of abelian varieties. Our proof uses techniques in mixed characteristics due to Dwork and Ogus.

  1. Removal of cyclic prefix in Adaptive Non-Contiguous OFDM for Dynamic Spectrum Access using DWT and WT

    OpenAIRE

    Saket kumar; Puspraj Tanwar

    2012-01-01

    Spectrum has valuable resource in wireless communication. In wireless communication some spectrum is waste due to uses of cyclic prefix (cp) in FFT multicarrier sampling. In place of FFT used DFT and wavelet transform function for removal of cyclic prefix. Wavelet based OFDM, particularly using DWT and WPT-OFDM as situations for Fourier- based OFDM with the focus on impulse noise effects. We begin by constructing the models of the inverse and forward transforms. We explain in detail each mode...

  2. Static and dynamic cyclic oxidation of 12 nickel-, cobalt-, and iron-base high-temperature alloys

    Science.gov (United States)

    Barrett, C. A.; Johnston, J. R.; Sanders, W. A.

    1978-01-01

    Twelve typical high-temperature nickel-, cobalt-, and iron-base alloys were tested by 1 hr cyclic exposures at 1038, 1093, and 1149 C and 0.05 hr exposures at 1093 C. The alloys were tested in both a dynamic burner rig at Mach 0.3 gas flow and in static air furnace for times up to 100 hr. The alloys were evaluated in terms of specific weight loss as a function of time, and X-ray diffraction analysis and metallographic examination of the posttest specimens. A method previously developed was used to estimate specific metal weight loss from the specific weight change of the sample. The alloys were then ranked on this basis. The burner-rig test was more severe than a comparable furnace test and resulted in an increased tendency for oxide spalling due to volatility of Cr in the protective scale and the more drastic cooling due to the air-blast quench of the samples. Increased cycle frequency also increased the tendency to spall for a given test exposure. The behavior of the alloys in both types of tests was related to their composition and their tendency to form scales. The alloys with the best overall behavior formed alpha-Al2O3 aluminate spinels.

  3. Cyclic viscoelastoplasticity of polypropylene/nanoclay composites

    DEFF Research Database (Denmark)

    Drozdov, A.; Christiansen, Jesper de Claville

    2012-01-01

    Observations are reported on isotactic polypropylene/organically modified nanoclay hybrids with concentrations of filler ranging from 0 to 5 wt.% in cyclic tensile tests with a stress–controlled program (oscillations between various maximum stresses and the zero minimum stress). A pronounced effect...

  4. Strongly Cyclic and Strongly Irreducible Decomposition

    Institute of Scientific and Technical Information of China (English)

    纪友清; 韩黎明

    2001-01-01

    Let W be an injective unilateral weighted shift, and let W(n) be the orthogonal direct sum of n copies of W. In this paper, we prove that, if the commutant of W is strictly cyclic, then W(n) has a unique (SI) decomposition with respect to similarity for every natural number n.

  5. Cyclic Triaxial Loading of Cohesionless Silty Sand

    DEFF Research Database (Denmark)

    Sabaliauskas, Tomas; Ibsen, Lars Bo

    2015-01-01

    To engineer efficient structures offshore, we need to extend our knowledge of soil response. Cyclic loading and high water pressure encountered offshore greatly influence cohesionless soil performance. Silty sand from Frederikshavn wind turbine farm was tested using single diameter height samples...

  6. Cyclic electron flow: facts and hypotheses.

    Science.gov (United States)

    Finazzi, Giovanni; Johnson, Giles N

    2016-09-01

    Over the last 15 years, research into the process of cyclic electron flow in photosynthesis has seen a huge resurgence. Having been considered by some in the early 1990s as a physiologically unimportant artefact, it is now recognised as essential to normal plant growth. Here, we provide an overview of the major developments covered in this special issue of photosynthesis research.

  7. Monopod bucket foundations under cyclic lateral loading

    DEFF Research Database (Denmark)

    Foglia, Aligi; Ibsen, Lars Bo

    The monopod bucket foundation can be a cost-reducing sub-structure for offshore wind turbines. To avoid problems during the turbine operation, the long-term effect of cyclic loading must be considered in the design of the foundation. In this paper a 1g testing rig is adopted to extend the knowled...

  8. Monopod Bucket Foundations Under Cyclic Lateral Loading

    DEFF Research Database (Denmark)

    Foglia, Aligi; Ibsen, Lars Bo

    2016-01-01

    The monopod bucket foundation has the potential to become a cost-reducing substructure for offshore wind turbines. To avoid problems during the energy converter operation, the long-term effect of cyclic loading must be considered in the design of the foundation. In this paper, a 1-g testing rig i...

  9. A New Cyclic Peptide from Schnabelia tetradonta

    Institute of Scientific and Technical Information of China (English)

    Hui DOU; Yan ZHOU; Shu lin PENG; Li Sheng DING

    2003-01-01

    A new cyclic octapeptide (schnabepeptide B) was isolated from the aerial part ofSchnabelia tetradonta (Sun) C. Y. Wu et C. Chen (Lamiaceae). Its structure was elucidated ascyclo-(NH-Trp-Gly1-Leu1-Gly2-Pro1-Pro2-Leu2-Pro3-CO) on the basis of extensive 2D NMR andMS spectra.

  10. Steady state oxygen reduction and cyclic voltammetry

    DEFF Research Database (Denmark)

    Rossmeisl, Jan; Karlberg, Gustav; Jaramillo, Thomas;

    2008-01-01

    The catalytic activity of Pt and Pt3Ni for the oxygen reduction reaction is investigated by applying a Sabatier model based on density functional calculations. We investigate the role of adsorbed OH on the activity, by comparing cyclic voltammetry obtained from theory with previously published...

  11. Hopf Algebroids and Their Cyclic Theory

    NARCIS (Netherlands)

    Kowalzig, N.

    2009-01-01

    The main objective of this thesis is to clarify concepts of generalised symmetries in noncommutative geometry (i.e., the noncommutative analogue of groupoids and Lie algebroids) and their associated (co)homologies. These ideas are incorporated by the notion of Hopf algebroids and Hopf-cyclic (co)hom

  12. Cyclic Cratonic Carbonates and Phanerozoic Calcite Seas.

    Science.gov (United States)

    Wilkinson, Bruce H.

    1982-01-01

    Discusses causes of cyclicity in cratonic carbonate sequences and evidence for and potential significance of postulated primary calcite sediment components in past Paleozoic seas, outlining problems, focusing on models explaining existing data, and identifying background. Future sedimentary geologists will need to address these and related areas…

  13. STUDY OF CYCLIC AMP IN HUMAN SEMEN

    Institute of Scientific and Technical Information of China (English)

    JIANGNing

    1989-01-01

    It had been observed that there was a close relationship between cyclic AMP and the motility, energy metabolism, capaeitation and acrosome reaction of spermatozoa. In this study a radio-immunoassay procedure for measuring cAMP concentration in sperm and

  14. Scale invariant density perturbations from cyclic cosmology

    Science.gov (United States)

    Frampton, Paul Howard

    2016-04-01

    It is shown how quantum fluctuations of the radiation during the contraction era of a comes back empty (CBE) cyclic cosmology can provide density fluctuations which re-enter the horizon during the subsequent expansion era and at lowest order are scale invariant, in a Harrison-Zel’dovich-Peebles sense. It is necessary to be consistent with observations of large scale structure.

  15. Hopf Algebroids and Their Cyclic Theory

    NARCIS (Netherlands)

    Kowalzig, N.|info:eu-repo/dai/nl/304349755

    2009-01-01

    The main objective of this thesis is to clarify concepts of generalised symmetries in noncommutative geometry (i.e., the noncommutative analogue of groupoids and Lie algebroids) and their associated (co)homologies. These ideas are incorporated by the notion of Hopf algebroids and Hopf-cyclic

  16. Cyclic deformation of NI/sub 3/(Al,Nb) single crystals at ambient and elevated temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Bonda, N.R.

    1985-01-01

    Cyclic tests were performed on Ni/sub 3/(Al,Nb) (..gamma..' phase) single crystals by using a servo-hydraulic machine under fully reversed plastic strain control at a frequency of 0.1-0.2 Hz at room temperature, 400/sup 0/C and 700/sup 0/C. Since the monotonic behavior is orientation dependent, three orientations were studied. Asymmetry in tensile and compressive stresses was observed in the cyclic hardening curves of specimens tested at these temperatures and they were discussed with regard to the model suggested by Paider et al for monotonic behavior. The stress levels in the cyclic stress-strain curves (CSSC) at room temperature depended on orientation and cyclic history. No CSSCs were established at 400/sup 0/C and 700/sup 0/C. The deformation in cyclic tests at small plastic strain amplitudes was found to be different from that in monotonic tests in the microplastic regions in which the deformation is believed to be carried by a small density of edge dislocations. But in cyclic deformation, to and from motion of dislocations trap the edge dislocations into dipoles and therefore screw dislocations will be forced to participate in the deformation. Cracks on the surfaces of specimens tested at room temperature and 400/sup 0/C were found to be of stage I type, whereas at 700/sup 0/C, they were of stage II type.

  17. Theory of cyclic creep of concrete based on Paris law for fatigue growth of subcritical microcracks

    Science.gov (United States)

    Bazant, Zdenek P.; Hubler, Mija H.

    2014-02-01

    Recent investigations prompted by a disaster in Palau revealed that worldwide there are 69 long-span segmental prestressed-concrete box-girder bridges that suffered excessive multi-decade deflections, while many more surely exist. Although the excessive deflections were shown to be caused mainly by obsolescence of design recommendations or codes for static creep, some engineers suspect that cyclic creep might have been a significant additional cause. Many investigators explored the cyclic creep of concrete experimentally, but a rational mathematical model that would be anchored in the microstructure and would allow extrapolation to a 100-year lifetime is lacking. Here it is assumed that the cause of cyclic creep is the fatigue growth of pre-existing microcracks in hydrated cement. The resulting macroscopic strain is calculated by applying fracture mechanics to the microcracks considered as either tensile or, in the form of a crushing band, as compressive. This leads to a mathematical model for cyclic creep in compression, which is verified and calibrated by laboratory test data from the literature. The cyclic creep is shown to be proportional to the time average of stress and to the 4th power of the ratio of the stress amplitude to material strength. The power of 4 is supported by the recent finding that, on the atomistic scale, the Paris law should have the exponent of 2 and that the exponent must increase due to scale bridging. Exponent 4 implies that cyclic creep deflections are enormously sensitive to the relative amplitude of the applied cyclic stress. Calculations of the effects of cyclic creep in six segmental prestressed concrete box girders indicate that, because of self-weight dominance, the effect on deflections absolutely negligible for large spans (>150m). For small spans (<40m) the cyclic creep deflections are not negligible but do not matter since the static creep causes in such bridges upward deflections. However, the cyclic creep is shown to cause

  18. Evaluation of the AZ31 cyclic elastic-plastic behaviour under multiaxial loading conditions

    Directory of Open Access Journals (Sweden)

    V. Anes

    2014-10-01

    Full Text Available Components and structures are designed based in their material’s mechanical properties such as Young's modulus or yield stress among others. Often those properties are obtained under monotonic mechanical tests but rarely under cyclic ones. It is assumed that those properties are maintained during the material fatigue life. However, under cyclic loadings, materials tend to change their mechanical properties, which can improve their strength (material hardening or degrade their mechanical capabilities (material softening or even a mix of both. This type of material behaviour is the so-called cyclic plasticity that is dependent of several factors such as the load type, load level, and microstructure. This subject is of most importance in design of structures and components against fatigue failures in particular in the case of magnesium alloys. Magnesium alloys due to their hexagonal compact microstructure have only 3 slip planes plus 1 twining plane which results in a peculiar mechanical behaviour under cyclic loading conditions especially under multiaxial loadings. Therefore, it is necessary to have a cyclic elastic-plastic model that allows estimating the material mechanical properties for a certain stress level and loading type. In this paper it is discussed several aspects of the magnesium alloys cyclic properties under uniaxial and multiaxial loading conditions at several stress levels taking into account experimental data. A series of fatigue tests under strain control were performed in hour glass specimens test made of a magnesium alloy, AZ31BF. The strain/stress relation for uniaxial loadings, axial and shear was experimentally obtained and compared with the estimations obtained from the theoretical elastic-plastic models found in the state-of-the-art. Results show that the AZ31BF magnesium alloy has a peculiar mechanical behaviour, which is quite different from the steel one. Moreover, the state of the art cyclic models do not capture in

  19. Regenerated Spider Silk Possess Mechanical Properties of Super- and Cyclic Contraction in Response to Environmental Humidity

    Science.gov (United States)

    Lu, Shan; Swaminathan, Ganesh; Evans, Samuel; Blackledge, Todd

    2013-06-01

    Major Ampullate (MA) spider silk is among the most impressive biomaterials due to its unparalleled mechanical properties, such as super-contraction and cyclic response to changes in humidity. Electro-spinning enables the generation of engineered silk fibers with controlled parameters and dimentions for various medical and commercial applications. However, their applications hinge on the ability to reproduce the mechanical properties such as a precise expansion-contraction response existed in natural silk fibers. Here, we successfully reproduced MA spider-silk fibers from solutions of natural MA silk proteins via electrospinning, which exhibit the super-contraction and cyclic response to humidity change in a manner mirroring the natural fibers.

  20. A Literature Study on the Effects of Cyclic Lateral Loading of Monopiles in Cohesionless Soils

    DEFF Research Database (Denmark)

    L. Rasmussen, Kristian; Hansen, Mette; Kirk Wolf, Torben

    Today, monopiles are the most typical foundation for offshore wind turbines. During their lifetime large diameter, stiff piles are subjected to millions of small cyclic loads due to environmental forces. The long-term cyclic loading can change the granular structure of the soil surrounding the pile....... This may change the stiffness of the soil-pile system and create an accumulated rotation of the pile. The behaviour of the soil-pile system is very complex and the influence of soil parameters, number of load cycles, and size, amplitude and characteristic of the load are examined, as they all contribute...

  1. Cyclical Patterns of Hand, Foot and Mouth Disease Caused by Enterovirus A71 in Malaysia.

    OpenAIRE

    Nmn NikNadia; I-Ching Sam; Sanjay Rampal; Wmz WanNorAmalina; Ghazali NurAtifah; Khebir Verasahib; Chia Ching Ong; MohdAidinniza MohdAdib; Yoke Fun Chan

    2016-01-01

    Enterovirus A71 (EV-A71) is an important emerging pathogen causing large epidemics of hand, foot and mouth disease (HFMD) in children. In Malaysia, since the first EV-A71 epidemic in 1997, recurrent cyclical epidemics have occurred every 2–3 years for reasons that remain unclear. We hypothesize that this cyclical pattern is due to changes in population immunity in children (measured as seroprevalence). Neutralizing antibody titers against EV-A71 were measured in 2,141 residual serum samples c...

  2. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome

    OpenAIRE

    Abdul-Sater, Ali A.; Tattoli, Ivan; Jin, Lei; Grajkowski, Andrzej; Levi, Assaf; Koller, Beverly H.; Irving C Allen; Beaucage, Serge L.; Fitzgerald, Katherine A.; Ting, Jenny P.-Y.; Cambier, John C.; Stephen E Girardin; Schindler, Christian

    2013-01-01

    Cyclic dinucleotides have been recently shown to induce type I interferon secretion. This study shows they also activate the NLRP3 inflammasome to stimulate robust IL-1b secretion through a novel pathway that does not generate mitochondrial ROS.

  3. Electrode calibration with a microfluidic flow cell for fast-scan cyclic voltammetry.

    Science.gov (United States)

    Sinkala, Elly; McCutcheon, James E; Schuck, Matthew J; Schmidt, Eric; Roitman, Mitchell F; Eddington, David T

    2012-07-07

    Fast-scan cyclic voltammetry (FSCV) is a common analytical electrochemistry tool used to measure chemical species. It has recently been adapted for measurement of neurotransmitters such as dopamine in awake and behaving animals (in vivo). Electrode calibration is an essential step in FSCV to relate observed current to concentration of a chemical species. However, existing methods require multiple components, which reduce the ease of calibrations. To this end, a microfluidic flow cell (μFC) was developed as a simple device to switch between buffer and buffer with a known concentration of the analyte of interest--in this case dopamine--in a microfluidic Y-channel. The ability to quickly switch solutions yielded electrode calibrations with faster rise times and that were more stable at peak current values. The μFC reduced the number of external electrical components and produced linear calibrations over a range of concentrations. To demonstrate this, an electrode calibrated with the μFC was used in FSCV recordings from a rat during the delivery of food reward--a stimulus that reliably evokes a brief increase in current due to the oxidation of dopamine. Using the linear calibration, dopamine concentrations were determined from the current responses evoked during the behavioral task. The μFC is able to easily and quickly calibrate FSCV electrode responses to chemical species for both in vitro and in vivo experiments.

  4. Basins of coexistence and extinction in spatially extended ecosystems of cyclically competing species.

    Science.gov (United States)

    Ni, Xuan; Yang, Rui; Wang, Wen-Xu; Lai, Ying-Cheng; Grebogi, Celso

    2010-12-01

    Microscopic models based on evolutionary games on spatially extended scales have recently been developed to address the fundamental issue of species coexistence. In this pursuit almost all existing works focus on the relevant dynamical behaviors originated from a single but physically reasonable initial condition. To gain comprehensive and global insights into the dynamics of coexistence, here we explore the basins of coexistence and extinction and investigate how they evolve as a basic parameter of the system is varied. Our model is cyclic competitions among three species as described by the classical rock-paper-scissors game, and we consider both discrete lattice and continuous space, incorporating species mobility and intraspecific competitions. Our results reveal that, for all cases considered, a basin of coexistence always emerges and persists in a substantial part of the parameter space, indicating that coexistence is a robust phenomenon. Factors such as intraspecific competition can, in fact, promote coexistence by facilitating the emergence of the coexistence basin. In addition, we find that the extinction basins can exhibit quite complex structures in terms of the convergence time toward the final state for different initial conditions. We have also developed models based on partial differential equations, which yield basin structures that are in good agreement with those from microscopic stochastic simulations. To understand the origin and emergence of the observed complicated basin structures is challenging at the present due to the extremely high dimensional nature of the underlying dynamical system.

  5. Fast-scan cyclic voltammetry analysis of dynamic serotonin reponses to acute escitalopram.

    Science.gov (United States)

    Wood, Kevin M; Hashemi, Parastoo

    2013-05-15

    The treatment of depression with selective serotonin reuptake inhibitors, SSRIs, is important to study on a neurochemical level because of the therapeutic variability experienced by many depressed patients. We employed the rapid temporal capabilities of fast scan cyclic voltammetry at carbon fiber microelectrodes to study the effects of a popular SSRI, escitalopram (ESCIT), marketed as Lexapro, on serotonin in mice. We report novel, dynamic serotonin behavior after acute ESCIT doses, characterized by a rapid increase in stimulated serotonin release and a gradual rise in serotonin clearance over 120 min. Dynamic changes after acute SSRI doses may be clinically relevant to the pathology of increased depression or suicidality after onset of antidepressant treatment. Due to the short-term variability of serotonin responses after acute ESCIT, we outline difficulties in creating dose response curves and we suggest effective means to visualize dynamic serotonin changes after SSRIs. Correlating chemical serotonin patterns to clinical findings will allow a finer understanding of SSRI mechanisms, ultimately providing a platform for reducing therapeutic variability.

  6. Simulation of reinforced concrete short shear wall subjected to cyclic loading

    Energy Technology Data Exchange (ETDEWEB)

    Parulekar, Y.M., E-mail: yogitap@barc.gov.in [Bhabha Atomic Research Centre (India); Reddy, G.R., E-mail: rssred@barc.gov.in [Bhabha Atomic Research Centre (India); Vaze, K.K. [Reactor Design and Development Group, Bhabha Atomic Research Centre (India); Pegon, P. [Joint Research Centre, Ispra (Italy); Wenzel, H. [Vienna Consulting Engineers, Vienna (Austria)

    2014-04-01

    Highlights: • Prediction of the capacity of squat shear wall using tests and analysis. • Modification of model of concrete in the softening part. • Pushover analysis using softened truss theory and FE analysis is performed. • Modified concrete model gives reasonable accurate peak load and displacement. • The ductility, ultimate load and also crack pattern can be accurately predicted. - Abstract: This paper addresses the strength and deformation capacity of stiff squat shear wall subjected to monotonic and pseudo-static cyclic loading using experiments and analysis. Reinforced concrete squat shear walls offer great potential for lateral load resistance and the failure mode of these shear walls is brittle shear mode. Shear strength of these shear walls depend strongly on softening of concrete struts in principal compression direction due to principal tension in other direction. In this work simulation of the behavior of a squat shear wall is accurately predicted by finite element modeling by incorporating the appropriate softening model in the program. Modification of model of concrete in the softening part is suggested and reduction factor given by Vecchio et al. (1994) is used in the model. The accuracy of modeling is confirmed by comparing the simulated response with experimental one. The crack pattern generated from the 3D model is compared with that obtained from experiments. The load deflection for monotonic loads is also obtained using softened truss theory and compared with experimental one.

  7. Synthesis and Characterization of Coumarin-Containing Cyclic Polymer and Its Photoinduced Coupling/Dissociation.

    Science.gov (United States)

    Li, Min; Fan, Wei; Hong, Chunyan; Pan, Caiyuan

    2015-12-01

    Cyclic polystyrene (PS) with a pendant coumarin group is prepared by the combination of atom transfer radical polymerization and "click" chemistry. Fluorescence resonance energy transfer process is observed in the fluorescence measurement of coumarin-containing PS, and cyclic PS exhibits stronger emission than that of its linear precursor. When cyclic PS is irradiated under UV light at λ = 365 nm, 8-shaped PS is achieved due to the dimerization of pendant coumarin group. Subsequently, 8-shaped PS can be divided into single macrocycle under UV irradiation at λ = 254 nm via the photocleavage of coumarin dimer. The photoinduced coupling and dissociation are monitored by UV/vis spectra and gel permeation chromatography (GPC).

  8. Literature review on cyclic lateral loading effects of mono-bucket foundations

    DEFF Research Database (Denmark)

    Kapitanov, Lachezar Rosenov; Duroska, Peter; Garcia, Cesar Antonio Garcia

    2016-01-01

    The renewable offshore energy sector is currently growing rapidly and there is a vast interest in optimization of the design procedures for the offshores wind turbines. Mono-Bucket can be a breakthrough in the sphere of offshore wind turbines foundations due to its lightness and fast installation...... and consequently cost-effectiveness compared to other common solutions. The long-term cyclic loading can cause degradation of soil-bucket system stiffness, which yields into accumulated and permanent deformations. Despite of the advantages, there is no standard procedure to design the foundation especially...... for assessing the accumulated deformations under environmental longterm loading. However, numerical and semi-empirical methods already used for offshore foundations can be adopted to take into account the effect of cyclic loading on Mono-Buckets. Among them, load-displacement techniques as cyclic p-y curves...

  9. A literature study on the effects of cyclic lateral loading of monopiles in cohesionless soils

    Energy Technology Data Exchange (ETDEWEB)

    Lange Rasmussen, K. [Niras, Aalborg (Denmark); Hansen, Mette; Kirk Wolf, T. [COWI, Kgs. Lyngby, (Denmark); Ibsen, L.B.; Ravn Roesen, H. [Aalborg Univ.. Dept. of Civil Engineering, Aalborg (Denmark)

    2013-06-15

    Today, monopiles are the most typical foundation for offshore wind turbines. During their lifetime large diameter, stiff piles are subjected to millions of small cyclic loads due to environmental forces. The long-term cyclic loading can change the granular structure of the soil surrounding the pile. This may change the stiffness of the soil-pile system and create an accumulated rotation of the pile. The behaviour of the soil-pile system is very complex and the influence of soil parameters, number of load cycles, and size, amplitude and characteristic of the load are examined, as they all contribute to the rotation and the change in stiffness. The scope of this article is to outline current design methods and the state of the art knowledge within the subject of long-term cyclic, lateral loading of piles. (Author)

  10. Effects of cyclic loading on temperature evolution of ULTIMET superalloy: experiment and theoretical modeling

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    High-speed, high-resolution infrared t hermography, as a non-contact, full-field, and nondestructive technique, was used to study the temperature variations of a cobalt-based ULTIMET alloy subjected to cyclic fatigue. During each fatigue cycle, the temperature oscillations, which were due to the thermal-elastic-plastic effects, were observed and related to stress-strain analyses. The change of temperature during fatigue was utilized to reveal the accumulation of fatigue damage . A constitutive model was developed for predicting the thermal and mechanical responses of ULTIMET alloy subjected to cyclic deformation. The model was constru cted in light of internal-state variables, which were developed to characterize the inelastic strain of the material during cyclic loading. The predicted stress -strain and temperature responses were found to be in good agreement with the e xperimental results.

  11. Simple Cyclic Movements As A Distinct Autism Feature - Computational Approach

    Directory of Open Access Journals (Sweden)

    Krzysztof Dobosz

    2013-01-01

    Full Text Available Diversity of symptoms in autism dictates a broad definition of Autism Spectrum of Disorders(ASD. Each year percentage of children diagnosed with ASD is growing. One common diag-nostic feature in individuals with ASD is the tendency to atypical simple cyclic movements.The motor brain activity seems to generate periodic attractor state that is hard to escape.Despite numerous studies scientists and clinicians do not know exactly if ASD is a result ofa simple but general mechanism, or a complex set of mechanisms, both on neural, molecularand system levels. Simulations using biologically relevant neural network model presentedhere may help to reveal simplest mechanisms that may be responsible for specific behavior.Abnormal neural fatigue mechanisms may be responsible for motor as well as many if notall other symptoms observed in ASD.

  12. Cyclic alternating pattern (CAP): the marker of sleep instability.

    Science.gov (United States)

    Parrino, Liborio; Ferri, Raffaele; Bruni, Oliviero; Terzano, Mario G

    2012-02-01

    Cyclic alternating pattern CAP is the EEG marker of unstable sleep, a concept which is poorly appreciated among the metrics of sleep physiology. Besides, duration, depth and continuity, sleep restorative properties depend on the capacity of the brain to create periods of sustained stable sleep. This issue is not confined only to the EEG activities but reverberates upon the ongoing autonomic activity and behavioral functions, which are mutually entrained in a synchronized oscillation. CAP can be identified both in adult and children sleep and therefore represents a sensitive tool for the investigation of sleep disorders across the lifespan. The present review illustrates the story of CAP in the last 25 years, the standardized scoring criteria, the basic physiological properties and how the dimension of sleep instability has provided new insight into pathophysiolology and management of sleep disorders.

  13. Experimental investigation of cyclic hygrothermal aging of hybrid composite

    KAUST Repository

    El Yagoubi, Jalal

    2013-04-05

    This work provides an experimental investigation of the cyclic hygrothermal aging of a hybrid composites. We aimed to propose a general framework in the view to further optimize polymer-based composites. It reports experimental data and relevant observations collected during an aging campaign (up to 2000 cycles) where anhydride-cured epoxy samples as well as composites samples are exposed to environmental conditions. The data gathered during the whole campaign reveals that (1) the polymer displays a non-classical sorption behavior (2) the volume change is correlated to the mass uptake (3) the elastic modulus is correlated to the glass transition temperature. Matrix and interface degradation of the hybrid composite is monitored by means of microstructural observations. © 2013 by the American Institute of Aeronautics and Astronautics, Inc. All rights reserved.

  14. Self-Organization of Mobile Populations in Cyclic Competition

    CERN Document Server

    Reichenbach, Tobias; Frey, Erwin

    2008-01-01

    The formation of out-of-equilibrium patterns is a characteristic feature of spatially-extended, biodiverse, ecological systems. Intriguing examples are provided by cyclic competition of species, as metaphorically described by the `rock-paper-scissors' game. Both experimentally and theoretically, such non-transitive interactions have been found to induce self-organization of static individuals into noisy, irregular clusters. However, a profound understanding and characterization of such patterns is still lacking. Here, we theoretically investigate the influence of individuals' mobility on the spatial structures emerging in rock-paper-scissors games. We devise a quantitative approach to analyze the spatial patterns self-forming in the course of the stochastic time evolution. For a paradigmatic model originally introduced by May and Leonard, within an interacting particle approach, we demonstrate that the system's behavior - in the proper continuum limit - is aptly captured by a set of stochastic partial differe...

  15. Multiaxial Cyclic Thermoplasticity Analysis with Besseling's Subvolume Method

    Science.gov (United States)

    Mcknight, R. L.

    1983-01-01

    A modification was formulated to Besseling's Subvolume Method to allow it to use multilinear stress-strain curves which are temperature dependent to perform cyclic thermoplasticity analyses. This method automotically reproduces certain aspects of real material behavior important in the analysis of Aircraft Gas Turbine Engine (AGTE) components. These include the Bauschinger effect, cross-hardening, and memory. This constitutive equation was implemented in a finite element computer program called CYANIDE. Subsequently, classical time dependent plasticity (creep) was added to the program. Since its inception, this program was assessed against laboratory and component testing and engine experience. The ability of this program to simulate AGTE material response characteristics was verified by this experience and its utility in providing data for life analyses was demonstrated. In this area of life analysis, the multiaxial thermoplasticity capabilities of the method have proved a match for the actual AGTE life experience.

  16. Recent developments in reassessment of jacket structures under extreme storm cyclic loading. Part 1: Overview

    Energy Technology Data Exchange (ETDEWEB)

    Eide, O.I.; Skallerud, B.H.; Johansen, A. [SINTEF Structures and Concrete, Trondheim (Norway); Amdahl, J. [Norwegian Inst. of Tech., Trondheim (Norway)

    1995-12-31

    An attractive approach to integrity assessment of jacket structures subjected to extreme storm cyclic loading is based on considerations of system strength rather than component strength. The system strength is determined by nonlinear pushover analyses. Nonlinear cyclic analyses are undertaken to determine if the system strength will be degraded due to repeated action of extreme waves. In the present series of papers, conditions for application and extension of such a procedure are addressed. Tubular members with D/t ratio in the range 35--80 were tested under extreme cyclic loading to investigate criteria for onset of local buckling and number of cycles to through thickness cracking. Tubular T-joints were tested under extreme cyclic loading to investigate degradation of cyclic capacity imposed by low cycle fatigue cracking. In part 1 of this series of papers, an overview of the developed methodology for integrity assessment of jacket structures is given. Conditions for application are addressed and illustrated by way of an example study.

  17. Environmental degradation of Opalinus Clay with cyclic variations in relative humidity

    Science.gov (United States)

    Wild, Katrin; Walter, Patric; Madonna, Claudio; Amann, Florian

    2016-04-01

    Clay shales are considered as favorable host rocks for nuclear waste repositories due to their low permeability, high sorption capacity and the potential for self-sealing. However, the favorable characteristics of the rock mass may change during tunnel excavation. Excavation is accompanied by stress redistribution and the development of an excavation damage zone. Furthermore, unloading and exposure to atmospheric conditions with a lower relative humidity (RH) causes desaturation of the rock mass close to the tunnel. This leads to shrinkage and the formation of desiccation cracks. During the open drift stage, seasonal atmospheric changes, especially RH variations, may alter the rock mass and influence the long-term crack evolution. This contribution discusses the influence of RH variation on the mechanical behavior of OPA. A series of specimens were exposed to short-term and long-term, stepwise cyclic RH variations between about 60 and 95% at constant temperature. Strains were measured using strain gauges to monitor the volumetric response during RH cycles. After each applied RH cycle, Brazilian tensile strength (BTS) tests were performed to identify whether there is a change in tensile strength due to environmental damage caused by the change in RH. Swelling and shrinkage of the specimens accompanied by irreversible volumetric expansion was observed as a consequence of the exposure to RH cycles. However, the irreversible strain was limited to the direction normal to bedding suggesting that internal damage is restricted along the bedding planes. No significant effect of cyclic RH variations on the BTS of the specimens was observed. The strength parallel to bedding remained constant over several cycles while the strength normal to bedding shows a slightly decreasing trend after 2 cycles. Furthermore, the water retention characteristics of the specimens were not altered significantly during stepwise RH cycling as the evolution of the water content was reversible

  18. Experimental study on seismic behavior of recycled-concrete-filled square steel tube columns under cyclic reversed loading%低周反复荷载下方钢管再生混凝土柱抗震性能试验研究

    Institute of Scientific and Technical Information of China (English)

    孟二从; 苏益声; 陈朋朋; 但宇

    2015-01-01

    为研究方钢管再生混凝土柱的抗震性能,以再生粗骨料取代率为变化参数,设计制作了4根不同取代率的试件,对其进行拟静力试验,研究分析其破坏形态、滞回曲线、骨架曲线、延性、耗能能力、刚度退化等力学性能指标。研究结果表明:方钢管再生混凝土柱的破坏形态与方钢管普通混凝土柱相似,均为柱脚的鼓曲破坏;随着再生骨料取代率的增大,试件的极限承载力会有所减小,但减小幅度不大;再生粗骨料取代率对试件的延性、耗能性能、刚度退化则没有明显的影响。%In order to study the seismic behavior of recycled-aggregate-concrete-filled square steel tube columns, four specimens with different replacement rates were test under the cyclic reversed loading. The destruction pattern and hysteretic performance, the hysteretic curves, skeleton curve, ductility, energy dissipation and stiffness degradation were analyzed. Research findings indicate that the destruction mode of recycled-aggregate-concrete-filled square steel tube columns is similar to that of concrete-filled square steel tubular columns. With the increase of the replacement ratio, the ulti-mate bearing capacity and measured value of he will be reduced, but the reduction is very tiny. The replacement ratio of recycled aggregate has no obvious effect on the ductility, energy dissipation and stiffness degradation.

  19. Autosomal dominant cyclic hematopoiesis: Genetics, phenotype, and natural history

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, S.E.; Stephens, K.; Dale, D.C. [Univ. of Washington, Seattle, WA (United States)

    1994-09-01

    Autosomal dominant cyclic hematopoiesis (ADCH; cyclic neutropenia) is a rare disorder manifested by transient neutropenia that recurs every three weeks. To facilitate mapping the ADCH gene by genetic linkage analysis, we studied 9 ADCH families with 42 affected individuals. Pedigrees revealed AD inheritance with no evidence for decreased penetrance. Similar intra- and interfamilial variable expression was observed, with no evidence to support heterogeneity. At least 3 families displayed apparent new mutations. Many adults developed chronic neutropenia, while offspring always cycled during childhood. Children displayed recurrent oral ulcers, gingivitis, lymphadenopathy, fever, and skin and other infections with additional symptoms. Interestingly, there were no cases of neonatal infection. Some children required multiple hospitalizations for treatment. Four males under age 18 died of Clostridium sepsis following necrotizing enterocolitis; all had affected mothers. No other deaths due to ADCH were found; most had improvement of symptoms and infections as adults. Adults experienced increased tooth loss prior to age 30 (16 out of 27 adults, with 9 edentulous). No increase in myelodysplasia, malignancy, or congenital anomalies was observed. Recombinant G-CSF treatment resulted in dramatic improvement of symptoms and infections. The results suggest that ADCH is not a benign disorder, especially in childhood, and abdominal pain requires immediate evaluation. Diagnosis of ADCH requires serial blood counts in the proband and at least one CBC in relatives to exclude similar disorders. Genetic counseling requires specific histories as well as CBCs of each family member at risk to determine status regardless of symptom history, especially to assess apparent new mutations.

  20. Volume Changes in Filled Rubber Under Uniaxial Cyclic Loading

    Directory of Open Access Journals (Sweden)

    Elina KAZINA

    2011-09-01

    Full Text Available Styrene-butadiene rubber, neat and filled with different silica content was investigated under uniaxial cyclic loading under a constant crosshead speed, with increasing deformation amplitude in subsequent loading cycles. Rubber was investigated in order to evaluate the reversibility of structure rearrangements, occurring in rubber when subjected to cyclic loading. Volume uniformly increases with growing strain and shows hysteresis at unloading. After complete unloading, no residual strain changes are observed. These data are in good conformity with the data of density measurements, which were made on specimens before and after the tests. By correlating data, obtained from volume changes and kinetics of hysteresis losses there were made assumptions on deformation mechanisms at different elongations. Deformational mechanisms, responsible for volume changes in rubber are reversible. Volume changes in specimen occur due to voids formation caused by filler microstructure breakage, rubber chains disentanglement, spaces between rubber macromolecular chains shrinkage, and chain slippage under higher elongations. Voids formation and deformation of rubber macromolecular chain reaches equilibrium state after certain elongation.http://dx.doi.org/10.5755/j01.ms.17.3.592

  1. Cyclic voltammetry of apple fruits: Memristors in vivo.

    Science.gov (United States)

    Volkov, Alexander G; Nyasani, Eunice K; Tuckett, Clayton; Blockmon, Avery L; Reedus, Jada; Volkova, Maya I

    2016-12-01

    A memristor is a resistor with memory that exhibits a pinched hysteretic relationship in cyclic voltammetry. Recently, we have found memristors in the electrical circuitry of plants and seeds. There are no publications in literature about the possible existence of memristors and electrical differentiators in fruits. Here we found that the electrostimulation of Golden Delicious or Arkansas Black apple fruits by bipolar periodic waves induces hysteresis loops with pinched points in cyclic voltammograms at low frequencies between 0.1MHz and 1MHz. At high frequencies of 1kHz, the pinched hysteresis loop transforms to a non-pinched hysteresis loop instead of a single line I=V/R for ideal memristors because the amplitude of electrical current depends on capacitance of a fruit's tissue and electrodes, frequency and direction of scanning. Electrostimulation of electrical circuits in apple fruits by periodic voltage waves also induces electrotonic potential propagation due to cell-to-cell electrical coupling with electrical differentiators. A differentiator is an electrical circuit in which the output of the circuit is approximately directly proportional to the rate of change of the input. The information gained from electrostimulation can be used to elucidate and to observe electrochemical and electrophysiological properties of electrical circuits in fruits.

  2. Rockfall triggering by cyclic thermal stressing of exfoliation fractures

    Science.gov (United States)

    Collins, Brian; Stock, Greg M.

    2016-01-01

    Exfoliation of rock deteriorates cliffs through the formation and subsequent opening of fractures, which in turn can lead to potentially hazardous rockfalls. Although a number of mechanisms are known to trigger rockfalls, many rockfalls occur during periods when likely triggers such as precipitation, seismic activity and freezing conditions are absent. It has been suggested that these enigmatic rockfalls may occur due to solar heating of rock surfaces, which can cause outward expansion. Here we use data from 3.5 years of field monitoring of an exfoliating granite cliff in Yosemite National Park in California, USA, to assess the magnitude and temporal pattern of thermally induced rock deformation. From a thermodynamic analysis, we find that daily, seasonal and annual temperature variations are sufficient to drive cyclic and cumulative opening of fractures. Application of fracture theory suggests that these changes can lead to further fracture propagation and the consequent detachment of rock. Our data indicate that the warmest times of the day and year are particularly conducive to triggering rockfalls, and that cyclic thermal forcing may enhance the efficacy of other, more typical rockfall triggers.

  3. Rockfall triggering by cyclic thermal stressing of exfoliation fractures

    Science.gov (United States)

    Collins, Brian D.; Stock, Greg M.

    2016-05-01

    Exfoliation of rock deteriorates cliffs through the formation and subsequent opening of fractures, which in turn can lead to potentially hazardous rockfalls. Although a number of mechanisms are known to trigger rockfalls, many rockfalls occur during periods when likely triggers such as precipitation, seismic activity and freezing conditions are absent. It has been suggested that these enigmatic rockfalls may occur due to solar heating of rock surfaces, which can cause outward expansion. Here we use data from 3.5 years of field monitoring of an exfoliating granite cliff in Yosemite National Park in California, USA, to assess the magnitude and temporal pattern of thermally induced rock deformation. From a thermodynamic analysis, we find that daily, seasonal and annual temperature variations are sufficient to drive cyclic and cumulative opening of fractures. Application of fracture theory suggests that these changes can lead to further fracture propagation and the consequent detachment of rock. Our data indicate that the warmest times of the day and year are particularly conducive to triggering rockfalls, and that cyclic thermal forcing may enhance the efficacy of other, more typical rockfall triggers.

  4. SCATTERING BY CYCLIC POLYMERS AND COPOLYMERS AT LARGE SCATTERING VECTORS

    NARCIS (Netherlands)

    KOSMAS, M; BENOIT, H; HADZIIOANNOU, G

    1994-01-01

    General formulae allowing the evaluation of the form factors of cyclic block copolymers are established and graphs for cyclic copolymers of the form (A-B)(N) are shown. When N is large, the linear and the cyclic copolymer have the same behaviour. It is possible to extend at large angle an analytical

  5. Cyclic cocycles on deformation quantizations and higher index theorems

    NARCIS (Netherlands)

    Pflaum, M.J.; Posthuma, H.; Tang, X.

    2010-01-01

    We construct a nontrivial cyclic cocycle on the Weyl algebra of a symplectic vector space. Using this cyclic cocycle we construct an explicit, local, quasi-isomorphism from the complex of differential forms on a symplectic manifold to the complex of cyclic cochains of any formal deformation quantiza

  6. SCATTERING BY CYCLIC POLYMERS AND COPOLYMERS AT LARGE SCATTERING VECTORS

    NARCIS (Netherlands)

    KOSMAS, M; BENOIT, H; HADZIIOANNOU, G

    1994-01-01

    General formulae allowing the evaluation of the form factors of cyclic block copolymers are established and graphs for cyclic copolymers of the form (A-B)(N) are shown. When N is large, the linear and the cyclic copolymer have the same behaviour. It is possible to extend at large angle an analytical

  7. Transient Spectroscopic Properties of [60]Fullerene-Containing Cyclic Sulphoxide

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The properties of the triplet excited state of [60]fullerene-containing cyclic sulphoxide have been investigated by time-resolved absorption spectroscopy. Transient absorption bands of [60]fullerene-containing cyclic sulphoxide showed two decay-components, which were attributed to triplet excited states of different spin multiplicity. The properties of photoexcited states of [60]fullerene-containing cyclic sulphoxide are also reported.

  8. Cyclic cocycles on deformation quantizations and higher index theorems

    NARCIS (Netherlands)

    Pflaum, M.J.; Posthuma, H.; Tang, X.

    2010-01-01

    We construct a nontrivial cyclic cocycle on the Weyl algebra of a symplectic vector space. Using this cyclic cocycle we construct an explicit, local, quasi-isomorphism from the complex of differential forms on a symplectic manifold to the complex of cyclic cochains of any formal deformation

  9. Helical Two-Revolutional Cyclical Surface

    Directory of Open Access Journals (Sweden)

    Tatiana Olejníková

    2009-12-01

    Full Text Available Paper presents a family of helical two-revolutional cyclical surfaces, which arecreated by movement of the circle alongside the helical cycloidal curve, where circle islocated in the curve normal plane and its centre is on this curve. Helical cycloidal curvecan be created by simultaneous revolution of a point about two different axes 3o, 2o and byscrewing about axis 1o in the space. Form of the helical cycloidal curve and also of thehelical two-revolutional cyclical surface is dependent on the relative position of the threeaxes of revolutions, on multiples of angular velocities and orientations of separaterevolutions. Analytic representation, classification of surfaces and some of their geometricproperties are derived.

  10. The Hall Algebra of Cyclic Serial Algebra

    Institute of Scientific and Technical Information of China (English)

    郭晋云

    1994-01-01

    In this paper, orders <1 and <2 on ((Z)+)nm are introduced and also regarded as orders on the isomorphism classes of finite modules of finite .cyclic algebra R with n simple modules and all the indecomposable projective modules have length m through a one-to-one correspondence between ((Z)+)nm and the isomorphism classes of finite R modules. Using this we prove that the Hall algebra of a cyclic serial algebra is identified with its Loewy subalgebra, and its rational extension has a basis of BPW type, and is a (((Z)+)nm, <2) filtered ring with the associated graded ring as an iterated skew polynomial ring. These results are also generalized to the Hall algebra of a tube over a finite field.

  11. Bouncing and cyclic string gas cosmologies

    CERN Document Server

    Greene, Brian; Marnerides, Stefanos

    2008-01-01

    We show that, in the presence of a string gas, simple higher-derivative modifications to the effective action for gravity can lead to bouncing and cyclic cosmological models. The modifications bound the expansion rate and avoid singularities at finite times. In these models the scale factors can have long loitering phases that solve the horizon problem. Adding a potential for the dilaton gives a simple realization of the pre-big bang scenario. Entropy production in the cyclic phase drives an eventual transition to a radiation-dominated universe. As a test of the Brandenberger-Vafa scenario, we comment on the probability of decompactifying three spatial dimensions in this class of models.

  12. Cyclic Nucleotide Signalling in Kidney Fibrosis

    Directory of Open Access Journals (Sweden)

    Elisabeth Schinner

    2015-01-01

    Full Text Available Kidney fibrosis is an important factor for the progression of kidney diseases, e.g., diabetes mellitus induced kidney failure, glomerulosclerosis and nephritis resulting in chronic kidney disease or end-stage renal disease. Cyclic adenosine monophosphate (cAMP and cyclic guanosine monophosphate (cGMP were implicated to suppress several of the above mentioned renal diseases. In this review article, identified effects and mechanisms of cGMP and cAMP regarding renal fibrosis are summarized. These mechanisms include several signalling pathways of nitric oxide/ANP/guanylyl cyclases/cGMP-dependent protein kinase and cAMP/Epac/adenylyl cyclases/cAMP-dependent protein kinase. Furthermore, diverse possible drugs activating these pathways are discussed. From these diverse mechanisms it is expected that new pharmacological treatments will evolve for the therapy or even prevention of kidney failure.

  13. Universal Cyclic Topology in Polymer Networks.

    Science.gov (United States)

    Wang, Rui; Alexander-Katz, Alfredo; Johnson, Jeremiah A; Olsen, Bradley D

    2016-05-01

    Polymer networks invariably possess topological defects: loops of different orders which have profound effects on network properties. Here, we demonstrate that all cyclic topologies are a universal function of a single dimensionless parameter characterizing the conditions for network formation. The theory is in excellent agreement with both experimental measurements of hydrogel loop fractions and Monte Carlo simulations without any fitting parameters. We demonstrate the superposition of the dilution effect and chain-length effect on loop formation. The one-to-one correspondence between the network topology and primary loop fraction demonstrates that the entire network topology is characterized by measurement of just primary loops, a single chain topological feature. Different cyclic defects cannot vary independently, in contrast to the intuition that the densities of all topological species are freely adjustable. Quantifying these defects facilitates studying the correlations between the topology and properties of polymer networks, providing a key step in overcoming an outstanding challenge in polymer physics.

  14. Detecting highly cyclic structure with complex eigenpairs

    CERN Document Server

    Klymko, Christine

    2016-01-01

    Many large, real-world complex networks have rich community structure that a network scientist seeks to understand. These communities may overlap or have intricate internal structure. Extracting communities with particular topological structure, even when they overlap with other communities, is a powerful capability that would provide novel avenues of focusing in on structure of interest. In this work we consider extracting highly-cyclic regions of directed graphs (digraphs). We demonstrate that embeddings derived from complex-valued eigenvectors associated with stochastic propagator eigenvalues near roots of unity are well-suited for this purpose. We prove several fundamental theoretic results demonstrating the connection between these eigenpairs and the presence of highly-cyclic structure and we demonstrate the use of these vectors on a few real-world examples.

  15. Generalized Toeplitz operators and cyclic vectors

    CERN Document Server

    Gassier, G; Zerouali, E H

    2003-01-01

    We give in this paper some asymptotic Von Neumann inequalities for power bounded operators in the class C subrho intersection C sub 1. and some spacial von Neumann inequalities associated with non zero elements of the point spectrum, when it is non void, of generalized Toeplitz operators. Introducing perturbed kernel, we consider classes C sub R which extend the classical classes C subrho. We give results about absolute continuity with respect to the Haar measure for operators in class C sub R intersection C sub 1. This allows us to give new results on cyclic vectors for such operators and provides invariant subspaces for their powers. Relationships between cyclic vectors for T and T* involving generalized Toeplitz operators are given and the commutativity of left brace T right brace', the commutant of T is discussed.

  16. Cyclic and Quasi-Cyclic LDPC Codes on Row and Column Constrained Parity-Check Matrices and Their Trapping Sets

    CERN Document Server

    Huang, Qin; Lin, Shu; Abdel-Ghaffar, Khaled

    2010-01-01

    This paper is concerned with construction and structural analysis of both cyclic and quasi-cyclic codes, particularly LDPC codes. It consists of three parts. The first part shows that a cyclic code given by a parity-check matrix in circulant form can be decomposed into descendant cyclic and quasi-cyclic codes of various lengths and rates. Some fundamental structural properties of these descendant codes are developed, including the characterizations of the roots of the generator polynomial of a cyclic descendant code. The second part of the paper shows that cyclic and quasi-cyclic descendant LDPC codes can be derived from cyclic finite geometry LDPC codes using the results developed in first part of the paper. This enlarges the repertoire of cyclic LDPC codes. The third part of the paper analyzes the trapping sets of regular LDPC codes whose parity-check matrices satisfy a certain constraint on their rows and columns. Several classes of finite geometry and finite field cyclic and quasi-cyclic LDPC codes with l...

  17. Past Eras In Cyclic Cosmological Models

    CERN Document Server

    Frampton, Paul H

    2009-01-01

    In infinitely cyclic cosmology past eras are discussed using set theory and transfinite numbers. One consistent scenario, already in the literature, is where there is always a countably infinite number, $\\aleph_0$, of universes and no big bang. I describe here an alternative where the present number of universes is $\\aleph_0$ and in the infinite past there was only a finite number of universes. In this alternative model it is also possible that there was no big bang.

  18. Cyclical Variability of Prominences, CMEs and Flares

    Indian Academy of Sciences (India)

    J. L. Ballester

    2000-09-01

    Solar flares, prominences and CMEs are well known manifestations of solar activity. For many years, qualitative studies were made about the cyclical behaviour of such phenomena. Nowadays, more quantitative studies have been undertaken with the aim to understand the solar cycle dependence of such phenomena as well as peculiar behaviour, such as asymmetries and periodicities, occurring within the solar cycle. Here, we plan to review the more recent research concerning all these topics.

  19. Transversality for Cyclic Negative Feedback Systems

    OpenAIRE

    2014-01-01

    Transversality of stable and unstable manifolds of hyperbolic periodic trajectories is proved for monotone cyclic systems with negative feedback. Such systems in general are not in the category of monotone dynamical systems in the sense of Hirsch. Our main tool utilized in the proofs is the so-called cone of high rank. We further show that stable and unstable manifolds between a hyperbolic equilibrium and a hyperbolic periodic trajectory, or between two hyperbolic equilibria with different di...

  20. Simple Current Actions of Cyclic Groups

    OpenAIRE

    Varga, Tamas

    2004-01-01

    Permutation actions of simple currents on the primaries of a Rational Conformal Field Theory are considered in the framework of admissible weighted permutation actions. The solution of admissibility conditions is presented for cyclic quadratic groups: an irreducible WPA corresponds to each subgroup of the quadratic group. As a consequence, the primaries of a RCFT with an order n integral or half-integral spin simple current may be arranged into multiplets of length k^2 (where k is a divisor o...

  1. Synthesis of a Cyclic Analogue of Galardin

    Institute of Scientific and Technical Information of China (English)

    马大为; 吴问根; 钱静; 郎深慧; 叶其壮

    2001-01-01

    A cyclic analogue 4 of galardin,a known MMP inhibitor,is designed to improve its selectivity.The synthesis of 4starts from dimethyl(S)-malate using diaselective alkylation and subsequent cyclization and amide formation as key steps.The compound 4 showed MMP inhibitory activity on all MMPs tested with IC50 ranging from 20.1 μM to 104 μM.

  2. General solution of the cyclic Leibniz rule

    Science.gov (United States)

    Kadoh, Daisuke; Ukita, Naoya

    2015-10-01

    We study the cyclic Leibniz rule (CLR) which was recently proposed as a new approach to the realization of supersymmetric quantum mechanics on the lattice. The CLR has an infinite number of solutions that give the different definitions of the lattice supersymmetric quantum mechanics. We show the general form of the solution for the naive symmetric difference operator and reveal the differences between the lattice models.

  3. Visualization of cyclic nucleotide dynamics in neurons

    Directory of Open Access Journals (Sweden)

    Kirill eGorshkov

    2014-12-01

    Full Text Available The second messengers cAMP and cGMP transduce many neuromodulatory signals from hormones and neurotransmitters into specific functional outputs. Their production, degradation and signaling are spatiotemporally regulated to achieve high specificity in signal transduction. The development of genetically encodable fluorescent biosensors has provided researchers with useful tools to study these versatile second messengers and their downstream effectors with unparalleled spatial and temporal resolution in cultured cells and living animals. In this review, we introduce the general design of these fluorescent biosensors and describe several of them in more detail. Then we discuss a few examples of using cyclic nucleotide fluorescent biosensors to study regulation of neuronal function and finish with a discussion of advances in the field. Although there has been significant progress made in understanding how the specific signaling of cyclic nucleotide second messengers is achieved, the mechanistic details in complex cell types like neurons are only just beginning to surface. Current and future fluorescent protein reporters will be essential to elucidate the role of cyclic nucleotide signaling dynamics in the functions of individual neurons and their networks.

  4. Cyclic dominance in evolutionary games: A review

    CERN Document Server

    Szolnoki, Attila; Jiang, Luo-Luo; Szczesny, Bartosz; Rucklidge, Alastair M; Perc, Matjaz

    2014-01-01

    Rock is wrapped by paper, paper is cut by scissors, and scissors are crushed by rock. This simple game is popular among children and adults to decide on trivial disputes that have no obvious winner, but cyclic dominance is also at the heart of predator-prey interactions, the mating strategy of side-blotched lizards, the overgrowth of marine sessile organisms, and the competition in microbial populations. Cyclical interactions also emerge spontaneously in evolutionary games entailing volunteering, reward, punishment, and in fact are common when the competing strategies are three or more regardless of the particularities of the game. Here we review recent advances on the rock-paper-scissors and related evolutionary games, focusing in particular on pattern formation, the impact of mobility, and the spontaneous emergence of cyclic dominance. We also review mean-field and zero-dimensional rock-paper-scissors models and the application of the complex Ginzburg-Landau equation, and we highlight the importance and use...

  5. Scale Factor Duality for Conformal Cyclic Cosmologies

    CERN Document Server

    dS, U Camara; Sotkov, G M

    2016-01-01

    The scale factor duality is a symmetry of dilaton gravity which is known to lead to pre-big-bang cosmologies. A conformal time version of the scale factor duality (SFD) was recently implemented as a UV/IR symmetry between decelerated and accelerated phases of the post-big-bang evolution within Einstein gravity coupled to a scalar field. The problem investigated in the present paper concerns the employment of the conformal time SFD methods to the construction of pre-big-bang and cyclic extensions of these models. We demonstrate that each big-bang model gives rise to two qualitatively different pre-big-bang evolutions: a contraction/expansion SFD model and Penrose's Conformal Cyclic Cosmology (CCC). A few examples of SFD symmetric cyclic universes involving certain gauged K\\"ahler sigma models minimally coupled to Einstein gravity are studied. We also describe the specific SFD features of the thermodynamics and the conditions for validity of the generalized second law in the case of Gauss-Bonnet (GB) extension ...

  6. Scale factor duality for conformal cyclic cosmologies

    Science.gov (United States)

    Camara da Silva, U.; Alves Lima, A. L.; Sotkov, G. M.

    2016-11-01

    The scale factor duality is a symmetry of dilaton gravity which is known to lead to pre-big-bang cosmologies. A conformal time version of the scale factor duality (SFD) was recently implemented as a UV/IR symmetry between decelerated and accelerated phases of the post-big-bang evolution within Einstein gravity coupled to a scalar field. The problem investigated in the present paper concerns the employment of the conformal time SFD methods to the construction of pre-big-bang and cyclic extensions of these models. We demonstrate that each big-bang model gives rise to two qualitatively different pre-big-bang evolutions: a contraction/expansion SFD model and Penrose's Conformal Cyclic Cosmology (CCC). A few examples of SFD symmetric cyclic universes involving certain gauged Kähler sigma models minimally coupled to Einstein gravity are studied. We also describe the specific SFD features of the thermodynamics and the conditions for validity of the generalized second law in the case of Gauss-Bonnet (GB) extension of these selected CCC models.

  7. Cyclical period changes in Z Chamaeleontis

    CERN Document Server

    Baptista, R; Oliveira, E; Vrielmann, S; Woudt, P A; Catalan, M S

    2002-01-01

    We report the identification of cyclical changes in the orbital period of the eclipsing dwarf nova Z Cha. We used times of mid-eclipse collected from the literature and our new eclipse timings to construct an observed-minus-calculated diagram covering 30 years of observations (1972-2002). The data present cyclical variations that can be fitted by a linear plus sinusoidal function with period 28+/-2 yr and amplitude 1.0+/-0.2 minute. The statistical significance of this period by an F-test is larger than 99.9%. The derived fractional period change, Delta P/P= 4.4 x 10^{-7}, is comparable to that of other short-period cataclysmic variables (CVs), but is one order of magnitude smaller than those of the long-period CVs. Separate fits to the first and second half of the data lead to ephemerides with quite different cycle periods and amplitudes, indicating that the variation is not sinusoidal or, most probably, is not strictly periodic. The observed cyclical period change is possibly caused by a solar-type magnetic...

  8. Cosmology and Cosmogony in a Cyclic Universe

    Indian Academy of Sciences (India)

    Jayant V. Narlikar; Geoffrey Burbidge; R. G. Vishwakarma

    2007-06-01

    In this paper we discuss the properties of the quasi-steady state cosmological model (QSSC) developed in 1993 in its role as a cyclic model of the universe driven by a negative energy scalar field. We discuss the origin of such a scalar field in the primary creation process first described by F. Hoyle & J. V. Narlikar forty years ago. It is shown that the creation processes which take place in the nuclei of galaxies are closely linked to the high energy and explosive phenomena, which are commonly observed in galaxies at all redshifts. The cyclic nature of the universe provides a natural link between the places of origin of the microwave background radiation (arising in hydrogen burning in stars), and the origin of the lightest nuclei (H, D, He3 and He4). It also allows us to relate the large scale cyclic properties of the universe to events taking place in the nuclei of galaxies. Observational evidence shows that ejection of matter and energy from these centers in the form of compact objects, gas and relativistic particles is responsible for the population of quasi-stellar objects (QSOs) and gamma-ray burst sources in the universe. In the later parts of the paper we briefly discuss the major unsolved problems of this integrated cosmological and cosmogonical scheme – the understanding of the origin of the intrinsic redshifts, and the periodicities in the redshift distribution of the QSOs.

  9. Scale factor duality for conformal cyclic cosmologies

    Energy Technology Data Exchange (ETDEWEB)

    Silva, University Camara da; Lima, A.L. Alves; Sotkov, G.M. [Departamento de Física - CCE,Universidade Federal de Espirito Santo, 29075-900, Vitoria ES (Brazil)

    2016-11-16

    The scale factor duality is a symmetry of dilaton gravity which is known to lead to pre-big-bang cosmologies. A conformal time version of the scale factor duality (SFD) was recently implemented as a UV/IR symmetry between decelerated and accelerated phases of the post-big-bang evolution within Einstein gravity coupled to a scalar field. The problem investigated in the present paper concerns the employment of the conformal time SFD methods to the construction of pre-big-bang and cyclic extensions of these models. We demonstrate that each big-bang model gives rise to two qualitatively different pre-big-bang evolutions: a contraction/expansion SFD model and Penrose’s Conformal Cyclic Cosmology (CCC). A few examples of SFD symmetric cyclic universes involving certain gauged Kähler sigma models minimally coupled to Einstein gravity are studied. We also describe the specific SFD features of the thermodynamics and the conditions for validity of the generalized second law in the case of Gauss-Bonnet (GB) extension of these selected CCC models.

  10. Critical current degradation in HTS wires due to cyclic mechanical strain

    NARCIS (Netherlands)

    Ryan, David T.; Li, Liang; Huang, Xianrui; Bray, J.W.; Laskaris, Evangelos T.; Sivasubramaniam, Kiruba; Gadre, Aniruddha D.; Fogerty, James M.; Harley, E.J.; Otto, A.; Ouden, den A.

    2005-01-01

    HTS wires, which may be used in many devices such as magnets and rotating machines, may be subjected to mechanical strains from electromagnetic, thermal and centripetal forces. In some applications these strains will be repeated several thousand times during the lifetime of the device. We have measu

  11. Spherical particles formation under biaxial cyclic loading due to mesotunneling effect

    Directory of Open Access Journals (Sweden)

    A. Shanyavskiy

    2015-07-01

    Full Text Available Fatigue fracture surfaces of Al-based alloys with fatigue striations pattern and such wear debris pattern as spherical particles were investigated fractographically, on the bases of the OG’e spectroscopic analysis. The sequence of events during fatigue crack edges opening was discovered when the elliptical or spherical shapes of wear debris build up on the fracture surface in crosspieces between mesotunnels under mode III of mode I fatigue crack opening because of volume rotation. The cause of black colour of places with fretting patterns on the fracture surfaces of Al-based alloys is discussed.

  12. Fractional Fourier domain analysis of cyclic multirate signal processing

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The cyclic filter banks, which are used widely in the image subband coding, refer to signal processing on the finite field. This study investigates the fractional Fourier domain (FRFD) analysis of cyclic multirate systems based on the fractional circular convolution and chirp period. The proposed theorems include the fractional Fourier domain analysis of cyclic decimation and cyclic interpolation, the noble identities of cyclic decimation and cyclic interpolation in the FRFD, the polyphase represen-tation of cyclic signal in the FRFD, and the perfect reconstruction condition for the cyclic filter banks in the FRFD. Furthermore, this paper proposes the design methods for perfect reconstruction cyclic filter bank and cyclic filter bank with chirp modulation in the FRFD. The proposed theorems extend the multirate signal processing in the FRFD, which also advance the applications of the theorems of filter bank in the FRFD on the finite signal field, such as digital image processing. At last, the proposed design methods for the cyclic filter banks in the FRFD are validated by simulations.

  13. Multiaxial elastoplastic cyclic loading of austenitic 316L steel

    Directory of Open Access Journals (Sweden)

    V. Mazánová

    2017-04-01

    Full Text Available Cyclic stress-strain response and fatigue damage character has been investigated in austenitic stainless steel 316L. Hollow cylindrical specimens have been cyclically deformed in combined tension-compression and torsion under constant strain rate condition and different constant strain and shear strain amplitudes. In-phase and 90° out-of-phase cyclic straining was applied and the stress response has been monitored. Cyclic hardening/softening curves were assessed in both channels. Cyclic softening followed for higher strain amplitudes by long-term cyclic hardening was observed. Cyclic stress-strain curves were determined. Study of the surface damage in fractured specimens revealed the types and directions of principal cracks and the sources of fatigue crack initiation in slip bands.

  14. Inhomogeneous deformation in INCONEL 718 during monotonic and cyclic loadings

    Science.gov (United States)

    Worthem, D. W.; Robertson, I. M.; Socie, D. F.; Altstetter, C. J.; Leckie, F. A.

    1990-01-01

    The paper concentrates on the relation between microstructural observations of the dislocation structures and the macroscopic deformation responses of both aged and homogenized precipitate-hardened alloys at room temperature. The deformation responses are compared to the cyclic deformation response of an aged precipitate-hardened alloy. Early in the deformation, one deformation band per grain and little evidence of work hardening are observed; with increased deformation, work hardening begins, more bands nucleate, and their spacing becomes similar to that in the aged material. It is pointed out that the degree of coarseness of inhomogeneous deformation is not a result of a softening process within the bands due to precipitate shearing, but it is a function of the amount of work hardening within the bands.

  15. Cosmological hysteresis in cyclic universe from membrane paradigm

    CERN Document Server

    Choudhury, Sayantan

    2016-01-01

    Cosmological hysteresis is a purely thermodynamical phenomenon caused by the gradient in pressure, hence the characteristic equation of state during the expansion and contraction phases of the universe are different, provided that the universe bounces and recollapses. During hysteresis pressure asymmetry is created due to the presence of a single scalar field in the dynamical process. Also such an interesting scenario has vivid implications in cosmology when applied to variants of modified gravity models described within the framework of membrane paradigm. Cyclic universe along with scalar field leads to the increase in the amplitude of the cosmological scale factor at each consecutive cycles of the universe. Detailed analysis shows that the conditions which creates a universe with an ever increasing expansion, depend on the signature of the hysteresis loop integral $\\oint pdV$ and on membrane model parameters.

  16. CARES/Life Ceramics Durability Evaluation Software Enhanced for Cyclic Fatigue

    Science.gov (United States)

    Nemeth, Noel N.; Powers, Lynn M.; Janosik, Lesley A.

    1999-01-01

    The CARES/Life computer program predicts the probability of a monolithic ceramic component's failure as a function of time in service. The program has many features and options for materials evaluation and component design. It couples commercial finite element programs--which resolve a component's temperature and stress distribution--to reliability evaluation and fracture mechanics routines for modeling strength-limiting defects. The capability, flexibility, and uniqueness of CARES/Life have attracted many users representing a broad range of interests and has resulted in numerous awards for technological achievements and technology transfer. Recent work with CARES/Life was directed at enhancing the program s capabilities with regards to cyclic fatigue. Only in the last few years have ceramics been recognized to be susceptible to enhanced degradation from cyclic loading. To account for cyclic loads, researchers at the NASA Lewis Research Center developed a crack growth model that combines the Power Law (time-dependent) and the Walker Law (cycle-dependent) crack growth models. This combined model has the characteristics of Power Law behavior (decreased damage) at high R ratios (minimum load/maximum load) and of Walker law behavior (increased damage) at low R ratios. In addition, a parameter estimation methodology for constant-amplitude, steady-state cyclic fatigue experiments was developed using nonlinear least squares and a modified Levenberg-Marquardt algorithm. This methodology is used to give best estimates of parameter values from cyclic fatigue specimen rupture data (usually tensile or flexure bar specimens) for a relatively small number of specimens. Methodology to account for runout data (unfailed specimens over the duration of the experiment) was also included.

  17. EC-FORC: A New Cyclic Voltammetry Based Method for Examining Phase Transitions and Predicting Equilibrium

    OpenAIRE

    2007-01-01

    We propose a new, cyclic-voltammetry based experimental technique that can not only differentiate between discontinuous and continuous phase transitions in an adsorbate layer, but also quite accurately recover equilibrium behavior from dynamic analysis of systems with a continuous phase transition. The Electrochemical first-order reversal curve (EC-FORC) diagram for a discontinuous phase transition (nucleation and growth), such as occurs in underpotential deposition, is characterized by a neg...

  18. Hairy carbon electrodes studied by cyclic voltammetry and battery discharge testing

    Science.gov (United States)

    Chung, Deborah D. L.; Shui, Xiaoping; Frysz, Christine A.

    1993-01-01

    Hairy carbon is a new material developed by growing submicron carbon filaments on conventional carbon substrates. Typical substrate materials include carbon black, graphite powder, carbon fibers, and glassy carbon. A catalyst is used to initiate hair growth with carbonaceous gases serving as the carbon source. To study the electrochemical behavior of hairy carbons, cyclic voltammetry (CV) and discharge testing were conducted. In both cases, hairy carbon results surpassed those of the substrate material alone.

  19. A one-dimensional stochastic approach to the study of cyclic voltammetry with adsorption effects

    OpenAIRE

    Adib J. Samin

    2016-01-01

    In this study, a one-dimensional stochastic model based on the random walk approach is used to simulate cyclic voltammetry. The model takes into account mass transport, kinetics of the redox reactions, adsorption effects and changes in the morphology of the electrode. The model is shown to display the expected behavior. Furthermore, the model shows consistent qualitative agreement with a finite difference solution. This approach allows for an understanding of phenomena on a microscopic level ...

  20. Assessing viscoelastic properties of chitosan scaffolds and validation with cyclical tests.

    Science.gov (United States)

    Ratakonda, Swapnika; Sridhar, Upasana M; Rhinehart, R Russell; Madihally, Sundararajan V

    2012-04-01

    We evaluated and modeled the viscoelastic characteristics of chitosan and chitosan-gelatin scaffolds prepared using a freeze-drying technique. Chitosan and chitosan-gelatin solutions (0.5 and 2 wt.%) were frozen at -80°C and freeze-dried. Using the scaffolds, uniaxial tensile properties were evaluated under physiological conditions (hydrated in phosphate buffered saline at 37°C) at a cross-head speed of 0.17 mms(-1) (10 mm min(-1)). From the break strain, the limit of strain per ramp was calculated to be 5% and the samples were stretched at a strain rate of 2.5%s(-1). The ramp-and-hold type of stress-relaxation test was performed for five successive stages. Chitosan and chitosan-gelatin showed nearly 90% relaxation of stress after each stage. The relaxation behavior was independent of the concentration of chitosan and gelatin. Also, changes in the microstructure of the tested samples were evaluated using an inverted microscope. The micrographs acquired after relaxation experiments showed orientation of pores, suggesting the retention of the stretched state even after many hours of relaxation. Based on these observations, two models (i) containing a hyper-elastic spring (containing two parameters) and (ii) retaining pseudo-components (containing three parameters) were developed in Visual Basic Applications accessed through MS Excel. The models were used to fit the experimental stress-relaxation data and the parameters obtained from modeling were used to predict their respective cyclic behaviors, which were compared with cyclical experimental results. These results showed that the model could be used to predict the cyclical behavior under the tested strain rates. The model predictions were also tested using cyclic properties at a lower strain rate of 0.0867%s(-1) (5%min(-1)) for 0.5 wt.% scaffolds but the model could not predict cyclical behavior at a very slow rate. In summary, the pseudo-component modeling approach can be used to model the sequential strain