WorldWideScience

Sample records for current research investigated

  1. Current Research Activities.

    Science.gov (United States)

    1975-02-01

    Biological oceanography, marine food chain dynamics, carbon cycling in the ocean. Martin, Seelye,Ph.D., Johns Hopkins. Geophysical fluid dynamics...currently under investigation, (Ahmed, Packard) 8. Amylase studies An assay for amylase activity has been adapted to measure zooplankton grazing. This...as a function of available food and of the biomass of copepods, was prescribed by sixteen equations: five, corresponding to copepodite stages (I to V

  2. Current Understandings of the Research-Practice Gap From the Viewpoint of Complementary Medicine Academics: A Mixed-Method Investigation.

    Science.gov (United States)

    Leach, Matthew J; Tucker, Basil

    Research plays an important role in advancing health and healthcare. However, much research evidence is not reflected in contemporary complementary and alternative medicine (CAM) practice. Understanding and addressing the reasons for this research-practice gap may have positive implications for quality of care. To shed light on the gap between research and CAM practice. Descriptive cross-sectional, mixed-method study. A total of 126 senior CAM academics across Australasia, Europe, UK, and North America. Participants completed a 30-item online survey and a semi-structured interview; both of which explored the research-practice gap in CAM. A total of 43 (34%) academics completed the survey, with 29 (67%) respondents undergoing an interview. There was general agreement among respondents that CAM research should be informed by practice, and practice informed by research; however, most agreed that this did not reflect the current situation. Translational issues were perceived to be the primary reason for the research-practice gap in CAM. Suggested strategies for closing the gap focussed mostly around improving CAM student/practitioner education and training, and researcher-practitioner engagement and collaboration. Study findings point toward the presence of a research-practice gap in CAM, with several factors likely to be instrumental in sustaining this gap. Attention now needs to focus on understanding the views of CAM clinicians on this issue. Insights gained from this research will help inform the development of a multi-modal strategy that will effectively target the barriers to change in order to bring CAM research and practice closer together. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Investigation of Current Driven Loudspeakers

    DEFF Research Database (Denmark)

    Schneider, Henrik; Agerkvist, Finn T.; Knott, Arnold

    2015-01-01

    Current driven loudspeakers have previously been investigated but the literature is limited and the advantages and disadvantages are yet to be fully identified. This paper makes use of a non-linear loudspeaker model to analyse loudspeakers with distinct non-linear characteristics under voltage...... and current drive. A multi tone test signal is used in the evaluation of the driving schemes since it resembles audio signals to a higher degree than the signals used in total harmonic distortion and intermodulation distortion test methods. It is found that current drive is superior over voltage drive in a 5...

  4. Xerostomia: current streams of investigation.

    Science.gov (United States)

    Quock, Ryan L

    2016-07-01

    Xerostomia is the subjective feeling of dry mouth, and it is often related to salivary hypofunction. Besides medication-related salivary hypofunction, Sjögren syndrome and head-and-neck radiation are two common etiologies that have garnered considerable attention. Approaches to treating and/or preventing salivary hypofunction in patients with these conditions will likely incorporate gene therapy, stem cell therapy, and tissue engineering. Advances in these disciplines are central to current research in the cure for xerostomia and will be key to eventual treatment. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Current Solid Mechanics Research

    DEFF Research Database (Denmark)

    Tvergaard, Viggo

    2016-01-01

    About thirty years ago James Lighthill wrote an essay on “What is Mechanics?” With that he also included some examples of the applications of mechanics. While his emphasis was on fluid mechanics, his own research area, he also included examples from research activities in solid mechanics....

  6. Current Models of Digital Scholarly Communication: Results of an Investigation Conducted by Ithaka for the Association of Research Libraries

    Science.gov (United States)

    Maron, Nancy L.; Smith, K. Kirby

    2008-01-01

    As electronic resources for scholarship proliferate, more and more scholars turn to their computers rather than to print sources to conduct their research. The decentralized distribution of these new model works can make it difficult to fully appreciate their scope and number, even for university librarians tasked with knowing about valuable…

  7. Current issues with research support

    Energy Technology Data Exchange (ETDEWEB)

    Russell, W.T.

    1996-03-01

    It would be difficult to condense current issues in nuclear reactor regulation to just a few minutes. So, let me start off by saying that I have not tried to give a comprehensive listing of issues that are currently facing the reactor program, but rather to select those that I thought were relevant as they relate to research activities. Use of probabilistic risk assessment in regulatory decisions; materials aging issues concerning steam generators and reactor vessels; high burnup fuels; accident management; and digital instrumentation and control, are just a sampling of the important issues that I want to talk about.

  8. Social networks user: current research

    Directory of Open Access Journals (Sweden)

    Agadullina E.R.

    2015-12-01

    Full Text Available The purpose of this article is to review current research studies focusing on the users of Facebook and their behaviors in social networks. This review is organized into two sections: 1 social-demographic characteristics (Age, Gender, Nationality; 2 personality characteristics (Neuroticism, Extraversion, Openness-to-Experience, Agreeableness, Conscientiousness, Narcissism, Self-esteem. The results showed that the information in the personal profile and online behavior are strongly connected with socio-demographic and personality characteristics

  9. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  10. Current research on aviation weather (bibliography), 1979

    Science.gov (United States)

    Turkel, B. S.; Frost, W.

    1980-01-01

    The titles, managers, supporting organizations, performing organizations, investigators and objectives of 127 current research projects in advanced meteorological instruments, forecasting, icing, lightning, visibility, low level wind shear, storm hazards/severe storms, and turbulence are tabulated and cross-referenced. A list of pertinent reference material produced through the above tabulated research activities is given. The acquired information is assembled in bibliography form to provide a readily available source of information in the area of aviation meteorology.

  11. 大学生时间洞察力现状调查研究%Investigation and Research on the Current Situation of College Students' Insight into Time

    Institute of Scientific and Technical Information of China (English)

    张云霞

    2016-01-01

    本文以洛阳市3所高校学生为被试,通过《时间洞察力问卷》调查大学生时间洞察力状况。研究表明:大学生对未来时间的理解和体验有明确的认知,总体时间洞察力有待加强;女生未来时间洞察力显著高于男生;男生现在宿命时间洞察力显著高于女生;大二学生现在宿命时间洞察力显著高于大一学生;理工科学生现在宿命时间洞察力显著高于文科学生。结论:大学生存在不佳的时间偏向,总体时间洞察力水平不高,急需采取措施提高时间洞察力水平。%With students from 3 colleges of Luoyang City as the subject,"questionnaire on insight into time"was used to investi-gate the current situation of college students' insight into time. It was found in the research that: college students have a clear knowledge on the understanding and experience of future time, but the general insight into time still needs to be improved; fe-male students' insight into future time is significantly higher than that of male students;male students' insight into present destiny time is significantly higher than that of female students; sopho-mores' insight into present destiny time is significantly higher than that of freshmen; science and engineering students' insight into present destiny time is significantly higher than that of liberal arts students. Conclusion: College students' tendency towards time is poor and the general level of their insight into time is low, so urgent measures should be taken to improve the level of insight into time.

  12. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1988-01-01

    Briefly describes 22 reports on language-related research relevant to Southeast Asia, detailing study aims, methodology, researchers, and sponsors for studies conducted in Brunei Darussalam, Indonesia, Malaysia, Philippines, Singapore, and Thailand. (CB)

  13. Cell Phones: Current Research Results

    Science.gov (United States)

    ... Potential Biological or Adverse Health Effects of Wireless Communication Devices World Health Organization: Electromagnetic Fields and Public Health: Mobile Phones International Agency for Research on Cancer Press ...

  14. Current concepts in cancer research

    Directory of Open Access Journals (Sweden)

    Ivan Kok Seng Yap

    2013-04-01

    Full Text Available Cancer research is an extremely broadtopic covering many scientific disciplines includingbiology (e.g. biochemistry and signal transduction,chemistry (e.g. drug discover and development,physics (e.g. diagnostic devices and even computerscience (e.g. bioinformatics. Some would argue thatcancer research will continue in much the same wayas it is by adding further layers of complexity to thescientific knowledge that is already complex and almostbeyond measure. But we anticipate that cancer researchwill undergo a dramatic paradigm shift due to therecent explosion of new discoveries in cancer biology.This review article focuses on the latest horizons incancer research concerning cancer epigenetics, cancerstem cells, cancer immunology and cancer metabolism.

  15. Integrated fundamental research on current collection

    Science.gov (United States)

    Kuhlmann-Wilsdorf, Doris; Tran, Leo

    1993-06-01

    The aim of our research was to add to the basic understanding in the area of current collection with particular emphasis on topics likely to benefit practical objectives. Under sponsorship of this contract, 23 papers were published in the international literature. Additionally, 13 invited lectures and 11 contributed lectures on various aspects of this research were delivered at universities, research laboratories, and international conferences by the principal investigator and co-workers. The development of a novel metal fiber material for sliding electrical contacts was continued with much success. This is expected to become very useful for making metal fiber brushed for homopolar motors/generators, as well as for EML armatures. Included in this report are title pages (and abstracts) for the 23 published papers.

  16. Current Research in Southeast Asia.

    Science.gov (United States)

    Beh, Yolanda

    1989-01-01

    Summaries of six language-related research projects are presented from Malaysia, Singapore, and Thailand. Topics include English as the instructional medium, teacher's use of language, Tamil language management, standardizing texts, cross-cultural business negotiations, and assessment of English language needs in computer science. (LB)

  17. Current Research Status of Allelopathy

    Directory of Open Access Journals (Sweden)

    AHMAD JUNAEDI

    2006-06-01

    Full Text Available The term of allelopathy refers to chemical interactions (inhibitory or stimulatory between plants, between plants and microorganisms, and between microorganisms. The wealth of information on the processes, procedures, and practices of allelopathy has contributed to understanding this field of science. Recently, researches of allelopathy have been conducted in laboratory, greenhouse, and field with multifaceted standpoint in some concerning area: (i allelochemicals identifications and screening test; (ii ecological and physiological aspects of allelopathy; (iii genetic studies and the possibilities of using plant breeding or genetic manipulation to enhance allelopathic varieties; (iv the use of allelopathic potential in the biological control, including as natural pesticide, of weeds and plant diseases as eco-friendly approach for sustainable agriculture scheme.

  18. Current Research on Antiepileptic Compounds

    Directory of Open Access Journals (Sweden)

    Cheng-Xi Wei

    2015-11-01

    Full Text Available Epilepsy affects about 1% of the world’s population. Due to the fact all antiepileptic drugs (AEDs have some undesirable side effects and about 30% of epileptic patients are not seizure-free with the existing AEDs, there is still an urgent need for the development of more effective and safer AEDs. Based on our research work on antiepileptic compounds and other references in recent years, this review covers the reported work on antiepileptic compounds which are classified according to their structures. This review summarized 244 significant anticonvulsant compounds which are classified by functional groups according to the animal model data, although there are some limitations in the data. This review highlights the properties of new compounds endowed with promising antiepileptic properties, which may be proven to be more effective and selective, and possibly free of unwanted side effects. The reviewed compounds represent an interesting possibility to overcome refractory seizures and to reduce the percentage of patients with a poor response to drug therapy.

  19. Investigation on current status of clinical research team building of traditional Chinese medicine%中医临床研究团队建设现状研究

    Institute of Scientific and Technical Information of China (English)

    李屹; 汪瑾; 朱惠蓉

    2014-01-01

    This article introduced several concepts about clinical research team building of traditional Chinese medicine and raised current problems:personnel structure and member collaboration of the team were poor,staff major in medicine had imbalanced knowledge structure within medical area and the structure of team learning margin was unitary. Members in the team had not been influenced enough by the team. Some suggestions were put forward at last. Reasonable structure of the team should be established,which included selecting the appropriate academic leader and backbone and training qualified excellent team members. Effective methods should be used to form a sense of superiority and mission among team members. Through understanding the main problems and tasks in different stages of the team, team members could provide assistance and support more innovatively,lively,and modernly for the whole team.%阐述了中医临床研究团队建设相关的几个概念,揭示了其目前存在的问题:中医临床研究团队的配置与协作有硬伤,医学人才“偏科”现象严重,研究团队学缘结构单一;研究团队对成员个人的影响力尚未形成。提出对策建议:构建合理的研究团队结构,包括选择合适的学术带头人,适合的学术研究骨干和培养合格乃至优秀的团队成员;通过有效手段促使团队成员形成团队优越感与使命感,通过了解研究团队建设不同阶段的主要问题与任务,以更新颖、活泼、现代化方式行使医院人力资源部门职能,为中医临床研究团队的建设提供协助与保障。

  20. Current challenges in dedifferentiated fat cells research.

    Science.gov (United States)

    Shah, Mickey; George, Richard L; Evancho-Chapman, M Michelle; Zhang, Ge

    2016-07-02

    Dedifferentiated fat cells show great promises as a novel cell source for stem cell research. It has many advantages when used for cell-based therapeutics including abundance, pluripotency, and safety. However, there are many obstacles researchers need to overcome to make the next big move in DFAT cells research. In this review, we summarize the current main challenges in DFAT cells research including cell culture purity, phenotypic properties, and dedifferentiation mechanisms. The common methods to produce DFAT cells as well as the cell purity issue during DFAT cell production have been introduced. Current approaches to improve DFAT cell purity have been discussed. The phenotypic profile of DFAT cells have been listed and compared with other stem cells. Further studies on elucidating the underlying dedifferentiation mechanisms will dramatically advance DFAT cell research.

  1. Current Care and Investigational Therapies in Achondroplasia.

    Science.gov (United States)

    Unger, Sheila; Bonafé, Luisa; Gouze, Elvire

    2017-04-01

    The goal of this review is to evaluate the management options for achondroplasia, the most common non-lethal skeletal dysplasia. This disease is characterized by short stature and a variety of complications, some of which can be quite severe. Despite several attempts to standardize care, there is still no widely accepted consensus. This is in part due to absence of concrete data on the incidence of sudden unexplained death in infants with achondroplasia and the best investigation for ascertaining which individuals could benefit from foramen magnum decompression surgery. In this review, we identify the different options of care and management for the various orthopedic, neurologic, and respiratory complications. In parallel, several innovative or drug repositioning therapies are being investigated that would restore bone growth but may also prevent complications. Achondroplasia is the most common non-lethal skeletal dysplasia. It is characterized by short stature and a variety of complications, some of which can be quite severe. Despite several attempts to standardize care, there is still no widely accepted consensus. This is in part due to absence of concrete data on the incidence of sudden unexplained death in infants with achondroplasia and the best investigation for ascertaining which individuals could benefit from foramen magnum decompression surgery. In this review, we identify the different options of care and management for the various orthopedic, neurologic, and respiratory complications. In parallel, several innovative or drug repositioning therapies are being investigated that would restore bone growth but may also prevent complications.

  2. Digital library research : current developments and trends

    OpenAIRE

    Shiri, Ali

    2003-01-01

    This column gives an overview of current trends in digital library research under the following headings: digital library architecture, systems, tools and technologies; digital content and collections; metadata; interoperability; standards; knowledge organisation systems; users and usability; legal, organisational, economic, and social issues in digital libraries.

  3. Current research of hepatic cirrhosis in China

    Institute of Scientific and Technical Information of China (English)

    Xi-Xian Yao; Shu-Lin Jiang; Dong-Mei Yao

    2005-01-01

    Hepatic cirrhosis is a common disease that poses a serious threat to public health, and is characterized by chronic,progressive and diffuse hepatic lesions preceded by hepaticfibrosis regardless of the exact etiologies. In recent years,considerable achievements have been made in China in research of the etiopathogenesis, diagnosis and especially the treatment of hepatic fibrosis, resulting in much improved prognosis of hepatic fibrosis and cirrhosis. In this paper, the authors review the current status of research in hepatic fibrosis, cirrhosis and their major complications.

  4. Medical Robots: Current Systems and Research Directions

    OpenAIRE

    Beasley, Ryan A.

    2012-01-01

    First used medically in 1985, robots now make an impact in laparoscopy, neurosurgery, orthopedic surgery, emergency response, and various other medical disciplines. This paper provides a review of medical robot history and surveys the capabilities of current medical robot systems, primarily focusing on commercially available systems while covering a few prominent research projects. By examining robotic systems across time and disciplines, trends are discernible that imply future capabilities ...

  5. Current clinical research in orthodontics: a perspective.

    Science.gov (United States)

    Baumrind, Sheldon

    2006-10-01

    This essay explores briefly the approach of the Craniofacial Research Instrumentation Laboratory to the systematic and rigorous investigation of the usual outcome of orthodontic treatment in the practices of experienced clinicians. CRIL's goal is to produce a shareable electronic database of reliable, valid, and representative data on clinical practice as an aid in the production of an improved environment for truly evidence-based orthodontic treatment.

  6. Medical Robots: Current Systems and Research Directions

    Directory of Open Access Journals (Sweden)

    Ryan A. Beasley

    2012-01-01

    Full Text Available First used medically in 1985, robots now make an impact in laparoscopy, neurosurgery, orthopedic surgery, emergency response, and various other medical disciplines. This paper provides a review of medical robot history and surveys the capabilities of current medical robot systems, primarily focusing on commercially available systems while covering a few prominent research projects. By examining robotic systems across time and disciplines, trends are discernible that imply future capabilities of medical robots, for example, increased usage of intraoperative images, improved robot arm design, and haptic feedback to guide the surgeon.

  7. Topics in current aerosol research (part2)

    CERN Document Server

    Hidy, G M

    1972-01-01

    Topics in Current Aerosol Research, Part 2 contains some selected articles in the field of aerosol study. The chosen topics deal extensively with the theory of diffusiophoresis and thermophoresis. Also covered in the book is the mathematical treatment of integrodifferential equations originating from the theory of aerosol coagulation. The book is the third volume of the series entitled International Reviews in Aerosol Physics and Chemistry. The text offers significant understanding of the methods employed to develop a theory for thermophoretic and diffusiophoretic forces acting on spheres in t

  8. INVESTIGATION OF BLOCKING ALGORITHM FOR TRANSFORMER CURRENT PROTECTIONS IN MAGNETIZING INRUSH CURRENT MODES

    Directory of Open Access Journals (Sweden)

    A. N. Kuzovlev

    2014-01-01

    Full Text Available Presents investigations on blocking  algorithm for transformer  current  protections  during magnetizing  inrush  current. The investigations have shown that the algorithm has high sensitivity and reliably determines magnetizing  inrush current modes.

  9. Leadership: current theories, research, and future directions.

    Science.gov (United States)

    Avolio, Bruce J; Walumbwa, Fred O; Weber, Todd J

    2009-01-01

    This review examines recent theoretical and empirical developments in the leadership literature, beginning with topics that are currently receiving attention in terms of research, theory, and practice. We begin by examining authentic leadership and its development, followed by work that takes a cognitive science approach. We then examine new-genre leadership theories, complexity leadership, and leadership that is shared, collective, or distributed. We examine the role of relationships through our review of leader member exchange and the emerging work on followership. Finally, we examine work that has been done on substitutes for leadership, servant leadership, spirituality and leadership, cross-cultural leadership, and e-leadership. This structure has the benefit of creating a future focus as well as providing an interesting way to examine the development of the field. Each section ends with an identification of issues to be addressed in the future, in addition to the overall integration of the literature we provide at the end of the article.

  10. Current and Future Research at DANCE

    Directory of Open Access Journals (Sweden)

    Jandel M.

    2015-01-01

    Full Text Available An overview of the current experimental program on measurements of neutron capture and neutron induced fission at the Detector for Advanced Neutron Capture Experiments (DANCE is presented. Three major projects are currently under way: 1 high precision measurements of neutron capture cross sections on Uranium isotopes, 2 research aimed at studies of the short-lived actinide isomer production in neutron capture on 235U and 3 measurements of correlated data of fission observables. New projects include developments of auxiliary detectors to improve the capability of DANCE. We are building a compact, segmented NEUtron detector Array at DANCE (NEUANCE, which will be installed in the central cavity of the DANCE array. It will provide experimental information on prompt fission neutrons in coincidence with the prompt fission gamma-rays measured by 160 BaF2 crystals of DANCE. Unique correlated data will be obtained for neutron capture and neutron-induced fission using the DANCE-NEUANCE experimental set up in the future.

  11. Current and Future Research at DANCE

    Science.gov (United States)

    Jandel, M.; Baramsai, B.; Bredeweg, T. A.; Couture, A.; Hayes, A.; Kawano, T.; Mosby, S.; Rusev, G.; Stetcu, I.; Taddeucci, T. N.; Talou, P.; Ullmann, J. L.; Walker, C. L.; Wilhelmy, J. B.

    2015-05-01

    An overview of the current experimental program on measurements of neutron capture and neutron induced fission at the Detector for Advanced Neutron Capture Experiments (DANCE) is presented. Three major projects are currently under way: 1) high precision measurements of neutron capture cross sections on Uranium isotopes, 2) research aimed at studies of the short-lived actinide isomer production in neutron capture on 235U and 3) measurements of correlated data of fission observables. New projects include developments of auxiliary detectors to improve the capability of DANCE. We are building a compact, segmented NEUtron detector Array at DANCE (NEUANCE), which will be installed in the central cavity of the DANCE array. It will provide experimental information on prompt fission neutrons in coincidence with the prompt fission gamma-rays measured by 160 BaF2 crystals of DANCE. Unique correlated data will be obtained for neutron capture and neutron-induced fission using the DANCE-NEUANCE experimental set up in the future.

  12. Numeric Investigation of Brain Tumor Influence on the Current Distributions During Transcranial Direct Current Stimulation.

    Science.gov (United States)

    Song, Bo; Wen, Peng; Ahfock, Tony; Li, Yan

    2016-01-01

    This study constructed a series of high-resolution realistic human-head models with brain tumors, and numerically investigated the influence of brain tumor's location and grade on the current distributions, under different electrode montages during tDCS. The threshold area and the peak current density were also derived and analyzed in the region of interest. The simulation result showed that it is safe to apply tDCS on the patients with brain tumors to treat their neuropsychiatric conditions and cancer pain caused by the tumor; although considerable changes of the current distributions are induced by the presence of a brain tumor. In addition, several observations on the global and local influences of tumor grade and possible edema have been made as well. These findings should be helpful for researchers and clinical doctors to treat patients with brain tumors. This study is also the first numerical study to fill in the gap of tDCS applications on the patients with brain tumors.

  13. Current research directions definition of economic security

    Directory of Open Access Journals (Sweden)

    Anna Falovych

    2013-05-01

    Full Text Available The article features the topical issue of the established level of the enterprise's economic security. The objective of this article is to research, to base and to supplement the tendency for generalization of the categorical system in order to clarify the matter meaning of the enterprise's economic security. The systematized analyses of the matter meaning of the enterprise's economic security were done by domestic and foreign scientists-economists. The results of the study were expounded and also some vital approaches to the definition of the enterprise's economic security were presented and proved particularly: strategically, resource-functional, marketable, combined, deductive, systematic and criminal.Based on the analyzed content-conceptual interpretations and detailed characteristics of each approach to the definition of this meaning, there was proposed its own meaning of the interpretation of the enterprise's economic security. A systematic approach was adopted due to the matters concerning enterprise's economic security. As in this approach the vital economic interests of thee enterprise were stipulated, also gained the topicality in the current crisis economic conditions

  14. CURRENT ANSTO RESEARCH ON WASTEFORM DEVELOPMENT

    Energy Technology Data Exchange (ETDEWEB)

    Vance, E.R.; Perera, D.S.; Stewart, M.W.A.; Begg, B.D.; Carter, M.L.; Day, R.A.; Moricca, S.; Smith, K.L.; Lumpkin, G.R.; Hanna, J.V.

    2003-02-27

    Current ANSTO scientific research on wasteform development for mainly high-level radioactive waste is directed towards practical applications. Titanate wasteform products we have developed or are developing are aimed at immobilization of: (a) tank wastes and sludges; (b) U-rich wastes from radioisotope production from reactor irradiation of UO2 targets; (c) Al-rich wastes arising from reprocessing of Al-clad fuels; (d) 99Tc; (e) high- Mo wastes arising from reprocessing of U-Mo fuels and (f) partitioned Cs-rich wastes. Other wasteforms include encapsulated zeolites or silica/alumina beads for immobilization of 129I. Wasteform production techniques cover hot isostatic and uniaxial pressing, sintering, and cold-crucible melting. In addition, building on previous work on speciation and leach resistance of Cs in cementitious products, we are studying geopolymers. Although we have a strong focus on candidate wasteforms for actual wastes, we have a considerable program directed at basic understanding of the wasteforms in regard to crystal chemistry, their dissolution behavior in aqueous media, radiation damage effects and processing techniques.

  15. The current status of research on resources recycling in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Seung-Hee; Kuh, Sung-Eun; Kim, Dong-Su [Ewha Womans University, Seoul (Korea)

    1999-03-31

    The current domestic research status for resources recycling has been reviewed by surveying the technical and review papers reported to some academic journals. The surveyed articles were classified based upon several categories, including recycling fields according to the kinds of recyclable materials, applied recycling technologies, organizations where the research was conducted, and references according to publication year and region. The survey showed that the recycling of metallurgical waste is being studied most actively. Also, the investigation of fly ash recycling is surveyed to be actively conducted. In the aspect of recycling technologies, chemical technologies are shown to be more widely applied than physical ones. For research-conducting organizations, academic institutes have been more active in the research of recycling field compared with national/private research institutes and industries. In the reference survey, English-written articles and the articles published between 1991-1995 period are shown to be most referred. (author). 6 refs., 7 tabs., 8 figs.

  16. Current Research on Effective Classroom Management.

    Science.gov (United States)

    Emmer, Edmund T.

    This presentation provides an overview of research on classroom management, emphasizing results from a program of research conducted at the Research and Development Center for Teacher Education (University of Texas) during the last 5 years. These studies, along with others, provide a basis for describing important dimensions of teacher behavior…

  17. Current trends in free software research

    OpenAIRE

    Navarro Bosch, Ramon; Vila Marta, Sebastià

    2009-01-01

    This report analyzes how scientific research is studying free software. We find which research is being done on free software by looking into scientific journals and conferences publications. The data thus obtained is analized and the most salient trends related to free software discovered. We also reviewed the main works published in each free software research area.

  18. Current investigations into carbon nanotubes for biomedical application

    Energy Technology Data Exchange (ETDEWEB)

    Li Xiaoming; Fan Yubo [Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191 (China); Watari, Fumio, E-mail: x.m.li@hotmail.co [Department of Biomedical Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586 (Japan)

    2010-04-15

    The nano-dimensionality of nature has logically given rise to the interest in using nanomaterials in the biomedical field. Currently, a lot of investigations into carbon nanotubes (CNTs), as one of the typical nanomaterials, are being made for biomedical application. In this review, five parts, such as cellular functions induced by CNTs, apatite formation on CNTs, CNT-based tissue engineering scaffold, functionalized CNTs for the delivery of genes and drugs and CNT-based biosensors, are stated, which might indicate that CNTs, with a range of unique properties, appear suited as a biomaterial and may become a useful tool for tissue engineering. However, everything has two parts and CNTs is not an exception. There are still concerns about cytotoxicity and biodegradation of CNTs. Chemical fictionalization may be one of the effective ways to improve the 'disadvantages' and utilize the 'advantages' of CNTs. One of their 'disadvantages', unbiodegradable property, may be utilized by creating monitors in in vivo-engineered tissues or nanosized CNT-based biosensors. Other promising research points, for example proteins adsorbed on CNTs, use of CNTs in combination with other biomaterials to achieve the goals of tissue engineering, mineralization of CNTs and standard toxicological tests for CNTs, are also described in the conclusion and perspectives part. (topical review)

  19. Investigation of casing inspection through tubing with pulsed eddy current

    Science.gov (United States)

    Fu, Yuewen; Yu, Runqiao; Peng, Xuewen; Ren, Shangkun

    2012-12-01

    Corrosion and cracks of casing string in oil wells is a serious problem on which little research has been done when inspecting casing through tubing. In this study, inspecting casing through tubing with pulsed eddy current is investigated. Longitudinal and transverse probes are centred inside the tubing to detect wall thinnings and cracks in casing. A time slice of induced voltage in the receiving coil of the probe is used as the feature to recognise defects. The experimental results show that large area wall thinnings and long cracks in casing are detected successfully through the tubing with appropriate inspection parameters. The probe's orientation to the crack is important and a particular discovery is that the transverse probe should be parallel to the transverse crack and not be perpendicular to it when inspecting. A method based on linear regression is proposed to estimate flaws in casing while wall thinning in the tubing occurs at the same location. The method is effective for large area thinning in casing when tubing thinning is wide.

  20. Statistics used in current nursing research.

    Science.gov (United States)

    Zellner, Kathleen; Boerst, Connie J; Tabb, Wil

    2007-02-01

    Undergraduate nursing research courses should emphasize the statistics most commonly used in the nursing literature to strengthen students' and beginning researchers' understanding of them. To determine the most commonly used statistics, we reviewed all quantitative research articles published in 13 nursing journals in 2000. The findings supported Beitz's categorization of kinds of statistics. Ten primary statistics used in 80% of nursing research published in 2000 were identified. We recommend that the appropriate use of those top 10 statistics be emphasized in undergraduate nursing education and that the nursing profession continue to advocate for the use of methods (e.g., power analysis, odds ratio) that may contribute to the advancement of nursing research.

  1. Investigating Design Research Landscapes through Exhibition

    DEFF Research Database (Denmark)

    Jönsson, Li; Hansen, Flemming Tvede; Mäkelä, Maarit;

    2013-01-01

    What characterizes a design research exhibition compared to a traditional design and art exhibition? How do you show the very materialities of the design experiments as a means for communicating knowledge of research and of practice? How do you present, review and utilize such an exhibition......? With those questions in mind, the intention and challenge for the Nordes 2013 Design Research Exhibition was to expand on current notions of staging research enquires in design research conference contexts. Artefacts, installations, performances, and other materialities that relate to the theme...... of the conference - Experiments in Design Research – were displayed as tools to express and communicate different design research enquires. Through this paper we will describe the Nordes exhibition as a specific case that renders questions visible in relation to how to utilize a design research exhibition...

  2. Current status of nuclear physics research

    Energy Technology Data Exchange (ETDEWEB)

    Bertulani, Carlos A. [Department of Physics and Astronomy, Texas A and M University-Commerce (United States); Hussein, Mahir S., E-mail: hussein@if.usp.br [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos, SP (Brazil). Dept. de Fisica

    2015-12-15

    In this review, we discuss the current status of research in nuclear physics which is being carried out in different centers in the world. For this purpose, we supply a short account of the development in the area which evolved over the last nine decades, since the discovery of the neutron. The evolution of the physics of the atomic nucleus went through many stages as more data became available. We briefly discuss models introduced to discern the physics behind the experimental discoveries, such as the shell model, the collective model, the statistical model, the interacting boson model, etc., some of these models may be seemingly in conflict with each other, but this was shown to be only apparent. The richness of the ideas and abundance of theoretical models attests to the important fact that the nucleus is a really singular system in the sense that it evolves from two-body bound states such as the deuteron, to few-body bound states, such as {sup 4}He, {sup 7}Li, {sup 9}Be, etc. and up the ladder to heavier bound nuclei containing up to more than 200 nucleons. Clearly, statistical mechanics, usually employed in systems with very large number of particles, would seemingly not work for such finite systems as the nuclei, neither do other theories which are applicable to condensed matter. The richness of nuclear physics stems from these restrictions. New theories and models are presently being developed. Theories of the structure and reactions of neutron-rich and proton-rich nuclei, called exotic nuclei, halo nuclei, or Borromean nuclei, deal with the wealth of experimental data that became available in the last 35 years. Furthermore, nuclear astrophysics and stellar and Big Bang nucleosynthesis have become a more mature subject. Due to limited space, this review only covers a few selected topics, mainly those with which the authors have worked on. Our aimed potential readers of this review are nuclear physicists and physicists in other areas, as well as graduate

  3. Current Status of Nuclear Physics Research

    Science.gov (United States)

    Bertulani, Carlos A.; Hussein, Mahir S.

    2015-12-01

    In this review, we discuss the current status of research in nuclear physics which is being carried out in different centers in the world. For this purpose, we supply a short account of the development in the area which evolved over the last nine decades, since the discovery of the neutron. The evolution of the physics of the atomic nucleus went through many stages as more data became available. We briefly discuss models introduced to discern the physics behind the experimental discoveries, such as the shell model, the collective model, the statistical model, the interacting boson model, etc., some of these models may be seemingly in conflict with each other, but this was shown to be only apparent. The richness of the ideas and abundance of theoretical models attests to the important fact that the nucleus is a really singular system in the sense that it evolves from two-body bound states such as the deuteron, to few-body bound states, such as 4He, 7Li, 9Be, etc. and up the ladder to heavier bound nuclei containing up to more than 200 nucleons. Clearly, statistical mechanics, usually employed in systems with very large number of particles, would seemingly not work for such finite systems as the nuclei, neither do other theories which are applicable to condensed matter. The richness of nuclear physics stems from these restrictions. New theories and models are presently being developed. Theories of the structure and reactions of neutron-rich and proton-rich nuclei, called exotic nuclei, halo nuclei, or Borromean nuclei, deal with the wealth of experimental data that became available in the last 35 years. Furthermore, nuclear astrophysics and stellar and Big Bang nucleosynthesis have become a more mature subject. Due to limited space, this review only covers a few selected topics, mainly those with which the authors have worked on. Our aimed potential readers of this review are nuclear physicists and physicists in other areas, as well as graduate students interested in

  4. Experimental Setup for the Investigation of Superconducting Persistent Current

    Science.gov (United States)

    2015-09-01

    NOTES 14. ABSTRACT We report on a recent experimental setup for the investigation of the relaxation rate of the persistent current in an assembly of...at cryo-temperatures in magnetic field at time scale of seconds to hours. 15. SUBJECT TERMS persistent current, 2G HTS, coated conductor, relaxation ... activation . One unknown aspect is the variation of the coils’ position with temperature from room to cryogenic. A better design of the coils assembly

  5. Some Current Themes in Functional Analysis Research.

    Science.gov (United States)

    Vollmer, Timothy R.; Smith, Richard G.

    1996-01-01

    This article discusses clinical application of functional analysis in developmental disabilities, reviewing issues related to treatment logic and development. The article then approaches functional analysis as a research method, reviewing three areas of research: analysis of diverse response topographies, analysis of basic behavioral processes,…

  6. Neuroimaging for psychotherapy research: current trends.

    Science.gov (United States)

    Weingarten, Carol P; Strauman, Timothy J

    2015-01-01

    This article reviews neuroimaging studies that inform psychotherapy research. An introduction to neuroimaging methods is provided as background for the increasingly sophisticated breadth of methods and findings appearing in psychotherapy research. We compiled and assessed a comprehensive list of neuroimaging studies of psychotherapy outcome, along with selected examples of other types of studies that also are relevant to psychotherapy research. We emphasized magnetic resonance imaging (MRI) since it is the dominant neuroimaging modality in psychological research. We summarize findings from neuroimaging studies of psychotherapy outcome, including treatment for depression, obsessive compulsive disorder (OCD), and schizophrenia. The increasing use of neuroimaging methods in the study of psychotherapy continues to refine our understanding of both outcome and process. We suggest possible directions for future neuroimaging studies in psychotherapy research.

  7. Current developments in toxicological research on arsenic.

    Science.gov (United States)

    Bolt, Hermann M

    2013-01-01

    There is a plethora of recent publications on all aspects relevant to the toxicology of arsenic (As). Over centuries exposures to arsenic continue to be a major public health problem in many countries. In particular, the occurrence of high As concentrations in groundwater of Southeast Asia receives now much attention. Therefore, arsenic is a high-priority matter for toxicological research. Key exposure to As are (traditional) medicines, combustion of As-rich coal, presence of As in groundwater, and pollution due to mining activities. As-induced cardiovascular disorders and carcinogenesis present themselves as a major research focus. The high priority of this issue is now recognized politically in a number of countries, research funds have been made available. Also experimental research on toxicokinetics and toxicodynamics and on modes of toxic action is moving very rapidly. The matter is of high regulatory concern, and effective preventive measures are required in a number of countries.

  8. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    2012-01-01

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge pert

  9. Current trends in chloroplast genome research

    African Journals Online (AJOL)

    USER

    2010-06-14

    Jun 14, 2010 ... organization and promising ability for transgenic expression. Therefore, cpDNA ... highly conserved in size, structure and gene content. (Olmstead and ... contain only 10% of the genes required for fully functional organelle whereas the ... concept (McFadden, 1999; Maliga, 2003; Howe, 2008). Currently 170 ...

  10. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge

  11. Loyalty Programmes : Current Knowledge and Research Directions

    NARCIS (Netherlands)

    Dorotic, Matilda; Bijmolt, Tammo H. A.; Verhoef, Peter C.

    2012-01-01

    Loyalty programmes (LPs) have increased in number and popularity, but their effects on customer behaviour remain equivocal, due to a lack of understanding of the drivers of LP effectiveness and insufficient generalizable conclusions across prior studies. This paper synthesizes current knowledge pert

  12. New Titan Saltation Threshold Experiments: Investigating Current and Past Climates

    Science.gov (United States)

    Bridges, N.; Burr, D. M.; Marshall, J.; Smith, J. K.; Emery, J. P.; Horst, S. M.; Nield, E.; Yu, X.

    2015-12-01

    Titan exhibits aeolian sand dunes that cover ~20% of its surface, attesting to significant sediment transport by the wind. Recent experiments in the Titan Wind Tunnel (TWT) at NASA Ames Research Center [1,2] found that the threshold friction speed needed to detach Titanian "sand" is about 50% higher than previous estimates based on theory alone [3], a result that might be explained by the low ratio of particle to fluid density on the body [1]. Following the successful completion of the initial Titan threshold tests, we are conducting new experiments that expand the pressure range above and below current Titan values. The basic experimental techniques are described in [1], with minor updates to the instrumentation as described in [2]. To reproduce the kinematic viscosity and particle friction Reynolds number equivalent to that expected for Titan's nitrogen atmosphere at 1.4 bars and 94 K requires that TWT be pressurized to 12.5 bars for air at 293K. In addition to running experiments at this pressure to reproduce previous results [1] and investigate low density (high density ratio) materials, TWT pressures of 3 and 8 bars are in the experimental matrix to understand threshold under past Titan conditions when the atmospheric pressure may have been lower [4]. Higher pressures, at 15 and 20 bars in TWT, are also being run to understand the putative effects of low density ratio conditions. Our experimental matrix for this follow-on work uses some of the same materials as previously used, including walnut shells, basalt, quartz, glass spheres, and various low density materials to better simulate the gravity-equivalent weight of Titan sand. For these experiments, the TWT is now equipped with a new high pressure Tavis transducer with sufficient sensitivity to measure freestream speeds of less than 0.5 m s-1 at 12.5 bars. New techniques include video documentation of the experiments. We are also investigating methods of measuring humidity of the wind tunnel environment and

  13. CURRENT STATE OF HISTORIC AND EDUCATIONAL RESEARCH

    Directory of Open Access Journals (Sweden)

    Magsumov Timur Albertovich

    2013-05-01

    Full Text Available In this paper we analyze the results of development of national historic and educational research at the turn of the XXth century; pinpoint obvious success and indicate problems and contradictory areas; give grounding to the development model of the XXth century Russian pedagogy; make suggestions on the strategy and tactics of further development of historic and educational science and suggest areas for further research. They are ‘new social history’ of education, professional education and teacher training, personified microhistory and history of local educational environment, genesis of didactic principles, ethno-pedagogy, country school, pedagogical diagnostics, Orthodox religious education, contemporary history of foreign pedagogy, pedagogical futurology. We prove the need in reassessment of certain studies’ viability. We draw the conclusion that historic and educational knowledge determines areas and instruments to understand the problems of educational issues, their roots and realize the existence of ways to solve them.

  14. Integrating Current Meteorological Research Through Club Fundraising

    Science.gov (United States)

    Gill, S. S.; Kauffman, C. M.

    2003-12-01

    Earth science programs whose focus is primarily an undergraduate education do not often have the funding to take students to very many conferences which could expose the student to new research as well as possible graduate programs and employment opportunities. Conferences also give the more enthusiastic and hardworking students a venue in which to present their research to the meteorological community. In addition, the California University services largely lower income counties, which make student attendance at conferences even more difficult even though the student in SW PA may be individually motivated. This issue is compounded by the fact that the Meteorology Concentration within the Earth Science department at Cal U is composed of only two full-time Professors, which limits the amount of research students can be exposed to within a classroom setting. New research ideas presented at conferences are thus an important mechanism for broadening what could be an isolated program. One way in which the meteorology program has circumvented the funding problem to a certain extent is through an active student club. With nearly 60 majors (3/4 of which are active in club activities, the meteorology club is able to execute a variety of fundraising activities. Money that is raised can then request from student services matching funds. Further money is given to clubs, which are very active not only in fundraising, but using that money for academic related activities. For the last 3 years the club budget has been in the neighborhood of \\$4500. The money has then been used to partially finance student registration and accommodation costs making conference attendance much more affordable. Normally 8-16 students attend conferences that they would otherwise not be able to attend without great expense. There are times when more than 16 students wish to attend, but travel arrangements prohibit more than 16. Moreover club money is also use to supplement student costs on a summer

  15. Sustainability in facilities management: an overview of current research

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev; Sarasoja, Anna-Liisa; Ramskov Galamba, Kirsten

    2016-01-01

    the emerging sub-discipline of sustainable facilities management (SFM) on research, an overview of current studies is needed. The purpose of this literature review is to provide exactly this overview. Design/methodology/approach: This article identifies and examines current research studies on SFM through...... indicated that the current research varies in focus, methodology and application of theory, and it was concluded that the current research primary addresses environmental sustainability, whereas the current research which takes an integrated strategic approach to SFM is limited. The article includes lists...... of reviewed journals and articles to support the further development of SFM in research and practice. Research limitations/implications: The literature review includes literature from 2007 to 2012, to manage the analytical process within the project period. However, with the current categorisation...

  16. Thoughts on the Problems of Research Method in the Investigation of Current Situation of Taekwondo%跆拳道运动现状调查方法存在的问题及几点思考

    Institute of Scientific and Technical Information of China (English)

    罗微; 李来

    2015-01-01

    近些年来,跆拳道运动的普及与发展促进了体育学术界对跆拳道运动的研究。本文以文献研究为主要方法,依据从1737篇以“跆拳道”为篇名中核心概念的文章中甄选出的25篇跆拳道运动现状调查的文章(不包括学校和经营性的以跆拳道俱乐部、跆拳道馆为篇名的现状调查),揭示出其调查方法中存在的六个问题,试图提起研究者们的注意,为促进调查方法的科学性、可靠性提供某些参考。%Among the 1737 articles whose core concept in its name is 'Taekwondo',25 articles (excluding surveys in the name of school and business Taekwondo clubs or taekwondo Kwan)on the survey of current situation of Taekwondo are chosen with the method of document research to expose the six problems in their survey methods. This paper aims to call researchers'attention to these problems and provides some guidance for scientific and reliable research methods.

  17. Intelligent multimedia surveillance current trends and research

    CERN Document Server

    Atrey, Pradeep K; Cavallaro, Andrea

    2013-01-01

    Intelligent multimedia surveillance concerns the analysis of multiple sensing inputs including video and audio streams, radio-frequency identification (RFID), and depth data. These data are processed for the automated detection and tracking of people, vehicles, and other objects. The goal is to locate moving targets, to understand their behavior, and to detect suspicious or abnormal activities for crime prevention. Despite its benefits, there is societal apprehension regarding the use of such technology, so an important challenge in this research area is to balance public safety and privacy.

  18. The current status of Kartini research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tri Wulan Tjiptono; Syarip

    1998-10-01

    The Kartini reactor reached the first criticality on January 25, 1979. In the first three years, the reactor power is limited up to 50 kW thermal power and on July 1, 1982 has been increased to 100 kW. It has been used as experiments facility by researcher of Atomic Energy National Agency and students of the Universities. Three beam tubes used as experiments facilities, the first, is used as a neutron source for H{sub 2}O-Natural Uranium Subcritical Assembly, the second, is developed for neutron radiography facility and the third, is used for gamma radiography facility. The other facilities are rotary rack and two pneumatic transfer systems, one for delayed neutron counting system and the other for the new Neutron Activation Analysis (NAA) facility. The rotary rack used for isotope production for NAA purpose (for long time irradiation), the delayed neutron counting system used for analysis the Uranium contents of the ores and the new NAA is provided for short live elements analysis. In the last three years the Reactor Division has a joint use program with the Nuclear Component and Engineering Center in research reactor instrumentation and control development. (author)

  19. Nanofluid technology : current status and future research.

    Energy Technology Data Exchange (ETDEWEB)

    Choi, S. U.-S.

    1998-10-20

    Downscaling or miniaturization has been a recent major trend in modern science and technology. Engineers now fabricate microscale devices such as microchannel heat exchangers, and micropumps that are the size of dust specks. Further major advances would be obtained if the coolant flowing in the microchannels were to contain nanoscale particles to enhance heat transfer. Nanofluid technology will thus be an emerging and exciting technology of the 21st century. This paper gives a brief history of the Advanced Fluids Program at Argonne National Laboratory (ANL), discusses the concept of nanofluids, and provides an overview of the R and D program at ANL on the production, property characterization, and performance of nanofluids. It also describes examples of potential applications and benefits of nanofluids. Finally, future research on the fundamentals and applications of nanofluids is addressed.

  20. A SURVEY OF CURRENT RESEARCH ON CAPTCHA

    Directory of Open Access Journals (Sweden)

    Walid Khalifa Abdullah Hasan

    2016-06-01

    Full Text Available The internet has been playing an increasingly important role in our daily life, with the availability of many web services such as email and search engines. However, these are often threatened by attacks from computer programs such as bots. To address this problem, CAPTCHA (Completely Automated Public Turing Test to Tell Computers and Humans Apart was developed to distinguish between computer programs and human users. Although this mechanism offers good security and limits automatic registration to web services, some CAPTCHAs have several weaknesses which allow hackers to infiltrate the mechanism of the CAPTCHA. This paper examines recent research on various CAPTCHA methods and their categories. Moreover it discusses the weakness and strength of these types.

  1. Experimental investigation of current free double layers in helicon plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Sahu, B. B. [Department of Applied Sciences and Humanities, Dronacharya College of Engineering, Gurgaon 123506 (India); Tarey, R. D. [Department of Physics, Indian Institute of Technology, New Delhi 110016 (India); Ganguli, A. [Centre for Energy Studies, Indian Institute of Technology, New Delhi 110016 (India)

    2014-02-15

    The paper presents investigations of current free double layer (CFDL) that forms in helicon plasmas. In contrast to the other work reporting on the same subject, in the present investigations the double layer (DL) forms in a mirror-like magnetic field topology. The RF compensated Langmuir probe measurements show multiple DLs, which are in connection with, the abrupt fall of densities along with potential drop of about 24 V and 18 V. The DLs strengths (e ΔV{sub p})/(k T{sub e}) are about 9.5 and 6, and the corresponding widths are about 6 and 5 D lengths. The potential drop is nearly equal to the thermal anisotropies between the two plasma regions forming the DL, which is present in the plateau region of mirror, unlike the earlier studies on the DL formation in the region of strong gradients in the magnetic field. Also, it presents a qualitative discussion on the mechanism of DL formation.

  2. Aespoe hard rock laboratory. Current research projects 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a `dress rehearsal` for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book `Aespoe Hard Rock Laboratory - 10 years of Research` published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

  3. Current Issues in LPP Research and Their Impact on Society

    Science.gov (United States)

    Darquennes, Jeroen

    2013-01-01

    After a very broad description of what language policy and planning is about this paper presents an overview of some of the current preoccupations of researchers focusing on language policy and planning as one of the blooming fields of applied linguistics. The current issues in language policy and planning research that are dealt with include…

  4. Current investigation and management of patients with syncope

    DEFF Research Database (Denmark)

    Dagres, Nikolaos; Bongiorni, Maria Grazia; Dobreanu, Dan

    2013-01-01

    for neurally mediated syncope. Physical manoeuvres were the most widely (93%) applied standard treatment for this syncope form. The results of this survey suggest that there are significant differences in the management of patients with syncope across Europe, specifically with respect to hospitalization rates......The aim of this European Heart Rhythm Association (EHRA) survey was to provide an insight into the current practice of work-up and management of patients with syncope among members of the EHRA electrophysiology research network. Responses were received from 43 centres. The majority of respondents...... (74%) had no specific syncope unit and only 42% used a standardized assessment protocol or algorithm. Hospitalization rates varied from 10% to 25% (56% of the centres) to >50% (21% of the centres). The leading reasons for hospitalization were features suggesting arrhythmogenic syncope (85...

  5. Current investigations into magnetic nanoparticles for biomedical applications.

    Science.gov (United States)

    Li, Xiaoming; Wei, Jianrong; Aifantis, Katerina E; Fan, Yubo; Feng, Qingling; Cui, Fu-Zhai; Watari, Fumio

    2016-05-01

    It is generally recognized that nanoparticles possess unique physicochemical properties that are largely different from those of conventional materials, specifically the electromagnetic properties of magnetic nanoparticles (MNPs). These properties have attracted many researchers to launch investigations into their potential biomedical applications, which have been reviewed in this article. First, common types of MNPs were briefly introduced. Then, the biomedical applications of MNPs were reviewed in seven parts: magnetic resonance imaging (MRI), cancer therapy, the delivery of drugs and genes, bone and dental repair, tissue engineering, biosensors, and in other aspects, which indicated that MNPs possess great potentials for many kinds of biomedical applications due to their unique properties. Although lots of achievements have been obtained, there is still a lot of work to do. New synthesis techniques and methods are still needed to develop the MNPs with satisfactory biocompatibility. More effective methods need to be exploited to prepare MNPs-based composites with fine microstructures and high biomedical performances. Other promising research points include the development of more appropriate techniques of experiments both in vitro and in vivo to detect and analyze the biocompatibility and cytotoxicity of MNPs and understand the possible influencing mechanism of the two properties. More comprehensive investigations into the diagnostic and therapeutic applications of composites containing MNPs with "core-shell" structure and deeper understanding and further study into the properties of MNPs to reveal their new biomedical applications, are also described in the conclusion and perspectives part.

  6. The International Permafrost Association: current initiatives for cryospheric research

    Science.gov (United States)

    Schollaen, Karina; Lewkowicz, Antoni G.; Christiansen, Hanne H.; Romanovsky, Vladimir E.; Lantuit, Hugues; Schrott, Lothar; Sergeev, Dimitry; Wei, Ma

    2015-04-01

    The International Permafrost Association (IPA), founded in 1983, has as its objectives to foster the dissemination of knowledge concerning permafrost and to promote cooperation among persons and national or international organizations engaged in scientific investigation and engineering work on permafrost. The IPA's primary responsibilities are convening International Permafrost Conferences, undertaking special projects such as preparing databases, maps, bibliographies, and glossaries, and coordinating international field programs and networks. Membership is through adhering national or multinational organizations or as individuals in countries where no Adhering Body exists. The IPA is governed by its Executive Committee and a Council consisting of representatives from 26 Adhering Bodies having interests in some aspect of theoretical, basic and applied frozen ground research, including permafrost, seasonal frost, artificial freezing and periglacial phenomena. This presentation details the IPA core products, achievements and activities as well as current projects in cryospheric research. One of the most important core products is the circumpolar permafrost map. The IPA also fosters and supports the activities of the Global Terrestrial Network on Permafrost (GTN-P) sponsored by the Global Terrestrial Observing System, GTOS, and the Global Climate Observing System, GCOS, whose long-term goal is to obtain a comprehensive view of the spatial structure, trends, and variability of changes in the active layer thickness and permafrost temperature. A further important initiative of the IPA are the biannually competitively-funded Action Groups which work towards the production of well-defined products over a period of two years. Current IPA Action Groups are working on highly topical and interdisciplinary issues, such as the development of a regional Palaeo-map of Permafrost in Eurasia, the integration of multidisciplinary knowledge about the use of thermokarst and permafrost

  7. Experimental Investigation of Turbulence Specifications of Turbidity Currents

    Directory of Open Access Journals (Sweden)

    B Firoozabadi

    2010-01-01

    Full Text Available The present study investigates the turbulence characteristic of turbidity current experimentally. The three-dimensional Acoustic-Doppler Velocimeter (ADV was used to measure the instantaneous velocity and characteristics of the turbulent flow. The experiments were conducted in a three-dimensional channel for different discharge flows, concentrations, and bed slopes. Results are expressed at various distances from the inlet, for all flow rates, slopes and concentrations as the distribution of turbulence energy, Reynolds stress and the turbulent intensity. It was concluded that the maximum turbulence intensity happens in both the interface and near the wall. Also, it was observed that the turbulence intensity reaches its minimum where maximum velocity occurs.

  8. The current status of environmental health research in Australia.

    Science.gov (United States)

    Gowland, Angela; Cook, Angus; Heyworth, Jane

    2012-01-01

    At present, the extent of environmental health research in Australia is unclear and there are no recent overarching reviews of national publications on the subject. This study investigates the current status of environmental health research in Australia using a bibliometric analysis. Three databases (Medline, Web of Science, and AUSTHealth) were used to access original, peer-reviewed journal articles with Australian data published between 1 January 2001 and 11 June 2010. A total of 337 articles from 174 different journal titles were used in the analysis and were classified according to 15 pre-determined environmental health areas. The highest number of articles related to water health and resources (66 articles), exposure to hazardous chemicals (57 articles), and air pollution including indoor air (58 articles). These areas made up 54% of the total publication output over the past 10 years. The amount of environmental health research published in Australia over the past 10 years, and the topics explored in these studies, is comparable to that of other countries of similar socio-economic status.

  9. Investigating the Impacts of Previous and Current Learning Experiences on Student Teachers' Teaching Experiences

    Science.gov (United States)

    Ögeyik, Muhlise Cosgun

    2016-01-01

    This study investigated the impacts of the previous and current learning experiences of the student teachers on their microteaching practices. The study pursued threefold research goals: to diagnose the microteaching stance, to treat it, and to explore and evaluate the progress. The participants were 24 undergraduate third year student teachers…

  10. Participation in a trauma-focused epidemiological investigation may result in sensitization for current health problems

    NARCIS (Netherlands)

    Verschuur, M.J.; Spinhoven, Ph.; van Emmerik, A.A.P.; Rosendaal, F.R.

    2008-01-01

    Objectives - Participation in health survey research may result in a worsening of self-assessed health status and enhanced service-use by increasing self-awareness of current health status. The present study investigated whether participation in a traumafocused epidemiological study sensitized parti

  11. What's Yours Is Mine: An Investigation of Current Copyright Policies of Education Journals

    Science.gov (United States)

    Meyer, Katrina A.

    2009-01-01

    This research investigated the current copyright policies of 21 education journals published by academic societies, universities and university presses, and commercial publishers. For the sample I chose only journals with a copyright policy on the journal or publisher web site, and I then analyzed the content of the policies in order to answer…

  12. Current status and future directions of research on facial attractiveness

    National Research Council Canada - National Science Library

    Kościński, Krzysztof

    2009-01-01

    The aim of the present paper was to evaluate the current state of knowledge on the perception of facial attractiveness and to assess the opportunity for research on poorly explored issues regarding facial preferences...

  13. Current Research on the Relative Effectiveness of Selected Media Characteristics.

    Science.gov (United States)

    Gulliford, Nancy L.

    The literature of research and theory on media, the psychology of learning, and the technology of instruction is reviewed. The focus is on discovering what is currently known about the intersection of these fields. Current thoughts and discoveries about brain structure and processing are discussed. The management of learning as a system is another…

  14. 流行病学论文的医学伦理意识现况调查与启示%Investigation on Current Condition of Medical Ethics Consciousness and its Enlightenment in Epidemiological Research

    Institute of Scientific and Technical Information of China (English)

    孟若谷; 翟炎冰; 陈森; 张晏畅; 张越伦; 赵剑云; 孙凤

    2012-01-01

    目的 描述近5年发表的流行病学论文的伦理意识现状,发现我国流行病学研究中存在的主要伦理学问题.方法 查阅某杂志2006~ 2010年刊登的文献,对其中以人为研究对象的原始论著的伦理意识进行描述.结果 共纳入论著749篇,分析显示:①论文中说明“经受试者知情同意”的论文为29.24%;声明“通过伦理委员会审批”的论文为6.94%;②伦理意识呈逐年上升趋势;③试验性研究论文伦理意识好于观察性研究;④不同研究机构和资金来源的研究伦理意识不同;⑤在采集受试者生物标本和隐私信息等方面的伦理意识较弱.结论 我国流行病学研究的伦理审查和知情同意意识较弱,建议应加强医学伦理学的宣传;发挥伦理委员会审查职能,规范伦理程序;积极完善期刊编审程序,提高编辑伦理素养,发挥期刊导向功能.%Objective:By describing the status of current ethics development in scientific literatures published on Chinese Journal of Epidemiology, to find the main ethical problems exist in epidemiological studies. Methods: Searching and reviewing papers on " Chinese Journal of Epidemiology" from2006 to2010, assess the medical ethical consciousness among the original studies focusing on human beings. Results; There are 749 Chinese articles were recruited, which show that; ①the proportion with announcements of "informed consent by the subjects" is 29. 24% ; the proportion with "possessing approvals from the ethic committees" announced is 6. 94%.②There is an increasing in ethics consciousness through these 5 years. ③Articles derived from trial studies have better ethics data than those from observational studies. ④Different research institutes and founding sources have different ethical review levels. ⑤Ethics consciousnesses are weak in biological specimens collection and privacy protection. Conclusion: The medical ethics consciousnesses in informed consent are still

  15. State of multicultural neuropsychological assessment in children: current research issues.

    Science.gov (United States)

    Byrd, Desiree; Arentoft, Alyssa; Scheiner, Diane; Westerveld, Michael; Baron, Ida Sue

    2008-09-01

    Scientific attention to cultural considerations in child neuropsychological assessment has not developed parallel to the focus these issues have received in adult and elderly neuropsychological assessment. There are limited data on the presence, magnitude, etiology, and implications of culture-related differences in cognitive test performance among children. This preliminary report reviews the available empirical literature on the current state of multicultural neuropsychological assessment in children. The review identified articles by searching PubMed and PsycINFO databases, and the tables of contents of Developmental Neuropsychology and Child Neuropsychology from 2003-2008. Of the 1,834 abstracts reviewed, ten papers met inclusion criteria for the review. Five studies were completed in America; four of these compared performance between ethnic groups while the fifth examined neighborhood level poverty indicators exclusively within African-American children. Of the five international studies, all established local normative data and/or were exploratory investigations of neuropsychological functions in specific cultural groups, including Taiwanese infants, South African youth, and bilingual British children. Taken together, the results yield important clinical and research data that begin to inform many of the complex and fascinating mechanisms by which ethnic identity and culture impact cognitive development and the neuropsychological assessment of children. A critique of the existing literature and directions for future research are provided.

  16. Current research projects on traffic conflicts technique studies.

    NARCIS (Netherlands)

    Hondel, M. van den & and Kraay, J.H.

    1979-01-01

    A review of current research concerning the development, evaluation and use of the traffic conflicts technique is presented. The 32 studies, selected from the IRRD data base, are listed alphabetically by names of countries and under countries by names of research organizations. The IRRD descriptions

  17. Educational Research in Mainland China: Current Situation and Developmental Trends

    Science.gov (United States)

    Sun, Miantao

    2011-01-01

    The influence of Confucian culture in Chinese Mainland China is reflected in the current situation and contextual trends of educational research content of educational thought of Confucianism, educational issues grounded on theoretical views of Confucianism, and the influence of the inclusiveness of Confucianism. In terms of research method, the…

  18. Current status and future research in motion planning

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Y.K.

    1995-07-01

    There have been numerous research efforts in the field of motion planning, resulting in many theoretical and practical results. We review the current status of existing motion planning algorithms, evaluate their completeness and efficiencies on modern computers, and suggest fruitful future research directions.

  19. Educational Research in Mainland China: Current Situation and Developmental Trends

    Science.gov (United States)

    Sun, Miantao

    2011-01-01

    The influence of Confucian culture in Chinese Mainland China is reflected in the current situation and contextual trends of educational research content of educational thought of Confucianism, educational issues grounded on theoretical views of Confucianism, and the influence of the inclusiveness of Confucianism. In terms of research method, the…

  20. Current and Future Research in Active Control of Lightweight, Flexible Structures Using the X-56 Aircraft

    Science.gov (United States)

    Ryan, John J.; Bosworth, John T.; Burken, John J.; Suh, Peter M.

    2014-01-01

    The X-56 Multi-Utility Technology Testbed aircraft system is a versatile experimental research flight platform. The system was primarily designed to investigate active control of lightweight flexible structures, but is reconfigurable and capable of hosting a wide breadth of research. Current research includes flight experimentation of a Lockheed Martin designed active control flutter suppression system. Future research plans continue experimentation with alternative control systems, explore the use of novel sensor systems, and experiments with the use of novel control effectors. This paper describes the aircraft system, current research efforts designed around the system, and future planned research efforts that will be hosted on the aircraft system.

  1. Investigation of Si(001) stable surfaces in alternating current heating

    Science.gov (United States)

    Doi, T.; Koguchi, M.

    2016-11-01

    The topography of a Si(001) vicinal surface is investigated using reflection electron microscopy (REM) during alternating current (AC) heating of the surface in ultra-high vacuum. The normal direction of the surface is slightly tilted from the [001] direction at θx or θy on the x or y axis (they are orthogonal directions in the Si(001) surface), and the average widths of the terraces (a or b in x or y axis) are determined by θx or θy; the direction perpendicular to the incidence electron beam on the surface is selected as the x (horizontal) axis in each REM image. Alternating current heating changes each initial surface from stable to double-domain (DD), in which 2 × 1 and 1 × 2 terraces are arranged regularly with approximately equal width, at its transition temperature Tc; the dimer rows are parallel to the x or y axis in the 1 × 2 or 2 × 1 terraces. There are two types of stable surfaces in the vicinal surface. At temperatures below its Tc, the surface with horizontally (vertically) long terraces, where b a), changes to a 2 × 1 (1 × 2) surface with wide 2 × 1 (1 × 2) and narrow 1 × 2 (2 × 1) terraces. The terrace, the short side of which is parallel to its dimer row direction, grows to create a stable surface by thermal diffusion of Si atoms at temperatures below Tc. During AC heating, thermal diffusion plays a key role in analyzing the kinetics of the atoms on the surface because the thermal effect acts as the driving force for the atoms that have not yet evaporated from the surface. Then, by evaporating atoms from the vicinal surface, AC heating creates a DD surface at temperatures between its Tc and 1100 °C and a rugged surface consisting of small 2 × 1 and 1 × 2 terraces at temperatures above 1100 °C.

  2. Image Information Retrieval: An Overview of Current Research

    Directory of Open Access Journals (Sweden)

    Abby A. Goodrum

    2000-01-01

    Full Text Available This paper provides an overview of current research in image information retrieval and provides an outline of areas for future research. The approach is broad and interdisciplinary and focuses on three aspects of image research (IR: text-based retrieval, content-based retrieval, and user interactions with image information retrieval systems. The review concludes with a call for image retrieval evaluation studies similar to TREC.

  3. Image Information Retrieval: An Overview of Current Research

    OpenAIRE

    Abby A. Goodrum

    2000-01-01

    This paper provides an overview of current research in image information retrieval and provides an outline of areas for future research. The approach is broad and interdisciplinary and focuses on three aspects of image research (IR): text-based retrieval, content-based retrieval, and user interactions with image information retrieval systems. The review concludes with a call for image retrieval evaluation studies similar to TREC.

  4. Paying research participants: a study of current practices in Australia.

    Science.gov (United States)

    Fry, C L; Ritter, A; Baldwin, S; Bowen, K J; Gardiner, P; Holt, T; Jenkinson, R; Johnston, J

    2005-09-01

    To examine current research payment practices and to inform development of clearer guidelines for researchers and ethics committees. Exploratory email based questionnaire study of current research participant reimbursement practices. A diverse sample of organisations and individuals were targeted. Australia. Contacts in 84 key research organisations and select electronic listservers across Australia. A total of 100 completed questionnaires were received with representations from a variety of research areas (for example, market, alcohol and drug, medical, pharmaceutical and social research). Open-ended and fixed alternative questions about type of research agency; type of research; type of population under study; whether payment is standard; amounts and mechanisms of payment; factors taken into account when deciding on payment practices; and whether payment policies exist. Reimbursement practice is highly variable. Where it occurs (most commonly for drug dependent rather than health professional or general population samples) it is largely monetary and is for time and out-of-pocket expenses. Ethics committees were reported to be often involved in decision making around reimbursement. Research subject payment practices vary in Australia. Researchers who do provide payments to research participants generally do so without written policy and procedures. Ethics committees have an important role in developing guidelines in this area. Specific guidelines are needed considering existing local policies and procedures; payment models and their application in diverse settings; case study examples of types and levels of reimbursement; applied definitions of incentive and inducement; and the rationale for diverse payment practices in different settings.

  5. Research Reproducibility in Geosciences: Current Landscape, Practices and Perspectives

    Science.gov (United States)

    Yan, An

    2016-04-01

    Reproducibility of research can gauge the validity of its findings. Yet currently we lack understanding of how much of a problem research reproducibility is in geosciences. We developed an online survey on faculty and graduate students in geosciences, and received 136 responses from research institutions and universities in Americas, Asia, Europe and other parts of the world. This survey examined (1) the current state of research reproducibility in geosciences by asking researchers' experiences with unsuccessful replication work, and what obstacles that lead to their replication failures; (2) the current reproducibility practices in community by asking what efforts researchers made to try to reproduce other's work and make their own work reproducible, and what the underlying factors that contribute to irreproducibility are; (3) the perspectives on reproducibility by collecting researcher's thoughts and opinions on this issue. The survey result indicated that nearly 80% of respondents who had ever reproduced a published study had failed at least one time in reproducing. Only one third of the respondents received helpful feedbacks when they contacted the authors of a published study for data, code, or other information. The primary factors that lead to unsuccessful replication attempts are insufficient details of instructions in published literature, and inaccessibility of data, code and tools needed in the study. Our findings suggest a remarkable lack of research reproducibility in geoscience. Changing the incentive mechanism in academia, as well as developing policies and tools that facilitate open data and code sharing are the promising ways for geosciences community to alleviate this reproducibility problem.

  6. Current states and perspectives of Czech educational research

    Directory of Open Access Journals (Sweden)

    Tomáš Janík

    2010-06-01

    Full Text Available The aim of the review study is to evaluate the current state of Czech educationalresearch and to offer possibilities of its further development. The paper has threeparts. In the first part, the author presents the context of the topic: the current changesin the financing of research and development in the Czech Republic; the avoiding ofthe term (social science is discussed along with the issue of institutional financing ofresearch and the various presently up-to-date methodologies of quality assessment inresearch. In the second part, the author analyses the current state of Czech educationalresearch – previous analyses of J. Pr°ucha, J. Mareš and E. Walterová and those carriedout by the Educational Research Centre are briefly summarised. In the third part, possibilitiesof further development of Czech educational research are offered. Developinga knowledge base of educational sciences is used as an example. First the nature andsubject of knowledge that is produced by research is analysed, then the difference betweenpedagogical research and research in education is discussed. Towards the end,relevant approaches are discussed along with research areas and types of knowledgeacquired by research.

  7. Agriculture for improved nutrition: the current research landscape.

    Science.gov (United States)

    Turner, Rachel; Hawkes, Corinna; Jeff, Waage; Ferguson, Elaine; Haseen, Farhana; Homans, Hilary; Hussein, Julia; Johnston, Deborah; Marais, Debbi; McNeill, Geraldine; Shankar, Bhavani

    2013-12-01

    Concern about food security and its effect on persistent undernutrition has increased interest in how agriculture could be used to improve nutritional outcomes in developing countries. Yet the evidence base for the impact of agricultural interventions targeted at improved nutrition is currently poor. To map the extent and nature of current and planned research on agriculture for improved nutrition in order to identify gaps where more research might be useful. The research, which was conducted from April to August 2012, involved developing a conceptual framework linking agriculture and nutrition, identifying relevant research projects and programs, devising and populating a "template" with details of the research projects in relation to the conceptual framework, classifying the projects, and conducting a gap analysis. The study identified a large number of research projects covering a broad range of themes and topics. There was a strong geographic focus on sub-Saharan Africa, and many studies were explicitly concerned with nutritional impacts on women and children. Although the study revealed a diverse and growing body of research, it also identified research gaps. Few projects consider the entire evidence chain linking agricultural input or practice to nutritional outcomes. There is comparatively little current research on indirect effects of agriculture on nutrition, or the effect of policies or governance, rather than technical interventions. Most research is focused on undernutrition and small farmer households, and few studies target consumers generally, urban populations, or nutrition-related non-communicable diseases. There is very little work on the cost-effectiveness of agricultural interventions. On the basis of these findings, we make suggestions for research investment and for broader engagement of researchers and disciplines in developing approaches to design and evaluate agricultural programs for improved nutrition.

  8. Investigation on a new inducer of pulsed eddy current thermography

    Science.gov (United States)

    He, Min; Zhang, Laibin; Zheng, Wenpei; Feng, Yijing

    2016-09-01

    In this paper, a new inducer of pulsed eddy current thermography (PECT) is presented. The use of the inducer can help avoid the problem of blocking the infrared (IR) camera's view in eddy current thermography technique. The inducer can also provide even heating of the test specimen. This paper is concerned with the temperature distribution law around the crack on a specimen when utilizing the new inducer. Firstly, relative mathematical models are provided. In the following section, eddy current distribution and temperature distribution around the crack are studied using the numerical simulation method. The best separation distance between the inducer and the specimen is also determined. Then, results of temperature distribution around the crack stimulated by the inducer are gained by experiments. Effect of current value on temperature rise is studied as well in the experiments. Based on temperature data, temperature features of the crack are discussed.

  9. Investigation on a new inducer of pulsed eddy current thermography

    Directory of Open Access Journals (Sweden)

    Min He

    2016-09-01

    Full Text Available In this paper, a new inducer of pulsed eddy current thermography (PECT is presented. The use of the inducer can help avoid the problem of blocking the infrared (IR camera’s view in eddy current thermography technique. The inducer can also provide even heating of the test specimen. This paper is concerned with the temperature distribution law around the crack on a specimen when utilizing the new inducer. Firstly, relative mathematical models are provided. In the following section, eddy current distribution and temperature distribution around the crack are studied using the numerical simulation method. The best separation distance between the inducer and the specimen is also determined. Then, results of temperature distribution around the crack stimulated by the inducer are gained by experiments. Effect of current value on temperature rise is studied as well in the experiments. Based on temperature data, temperature features of the crack are discussed.

  10. The Development and Current State of Translation Process Research

    DEFF Research Database (Denmark)

    Lykke Jakobsen, Arnt

    2014-01-01

    The development and current state of translation process research ch Arnt Lykke Jakobsen Copenhagen Business School lInterest in process-oriented translation studies has been intense for the past almost half a century. Translation process research (TPR) is the label we have used to refer to a spe......The development and current state of translation process research ch Arnt Lykke Jakobsen Copenhagen Business School lInterest in process-oriented translation studies has been intense for the past almost half a century. Translation process research (TPR) is the label we have used to refer...... to a special descriptive, empirical, experimental approach to translation studies based on close, technology-supported observation of translational (micro)behaviour. Fundamentally, TPR is based on software which logs a translator’s keystrokes on a computer keyboard in time in combination with an eyetracker...

  11. Curating research data a handbook of current practice

    CERN Document Server

    Johnston, Lisa R

    2017-01-01

    Curating Research Data, Volume Two: A Handbook of Current Practice guides you across the data lifecycle through the practical strategies and techniques for curating research data in a digital repository setting. The data curation steps for receiving, appraising, selecting, ingesting, transforming, describing, contextualizing, disseminating, and preserving digital research data are each explored, and then supplemented with detailed case studies written by more than forty international practitioners from national, disciplinary, and institutional data repositories. The steps in this volume detail the sequential actions that you might take to curate a data set from receiving the data (Step 1) to eventual reuse (Step 8). Data curators, archivists, research data management specialists, subject librarians, institutional repository managers, and digital library staff will benefit from these current and practical approaches to data curation.

  12. [Physiotherapeutic care marketing research: current state-of-the art].

    Science.gov (United States)

    Babaskin, D V

    2011-01-01

    Successful introduction of modern technologies into the national health care systems strongly depends on the current pharmaceutical market situation. The present article is focused on the peculiarities of marketing research with special reference to physiotherapeutic services and commodities. Analysis of the structure and sequence of marketing research processes is described along with the methods applied for the purpose including their support by the use of Internet resources and technologies.

  13. A Preliminary Investigation of Current Practices in American Youth Theatres.

    Science.gov (United States)

    Regan, F. Scott

    1983-01-01

    Summarizes results of a survey of youth theatres on (1) theatre goals; (2) staff training and courses offered; (3) organization and funds; and (4) teachers' knowledge of actor training, child and adolescent psychology, playwriting trends in children's theatre, and current theoretical writings. (PD)

  14. Current research status of immunology in the genomic era

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    This review updates the current status of immunology research under the influence of genomics,both conceptually and technologically.It particularly highlights the advantages of employing the high-throughput and large-scale technology,the large genomic database,and bioinformatic power in the immunology research.The fast development in the fields of basic immunology,clinical immunology(tumor and infectious immunology) and vaccine designing is illustrated with respect to the successful usage of genomic strategy.We also speculate the future research directions of immunology in the era of genomics and post-genomics.

  15. Current research status of immunology in the genomic era

    Institute of Scientific and Technical Information of China (English)

    LI HaoWen; LI dinZhi; ZHAO GuoPing; WANG Ying

    2009-01-01

    This review updates the current status of immunology research under the influence of genomics, both conceptually and technologically. It particularly highlights the advantages of employing the high-throughput and large-scale technology, the large genomic database, and bioinformatic power in the immunology research. The fast development in the fields of basic immunology, clinical immunology (tumor and infectious immunology) and vaccine designing is illustrated with respect to the successful usage of genomic strategy. We also speculate the future research directions of immunology in the era of genomics and post-genomics.

  16. Changing Currents in Second Language Writing Research: A Colloquium.

    Science.gov (United States)

    Matsuda, Paul Kei; Canagarajah, A. Suresh; Harklau, Linda; Hyland, Ken; Warschauer, Mark

    2003-01-01

    This article is based on an invited colloqium on second language (L) writing presented at the 200 meeting of the American Association for Applied Linguistics. The colloquium featured five second language writing researchers two discussed some of the important currents that have shaped the field of second language writing. (Author/VWL)

  17. Current Status and Advancements in Research of Plantation Nutrient Cycling

    Institute of Scientific and Technical Information of China (English)

    LI Run; ZHANG Changshun; SUN Yongyu

    2006-01-01

    This paper introduces concepts and current research status of plantation nutrients cyclings, and analyzes main contents of plantation nutrients cycling as nutrients contents, accumulation and distribution of nutrients elements, understory species and forest litter. At the same time, the paper summarizes the problems in plantation nutrients cycling and its prospects.

  18. Communicative Language Testing: Current Issues and Future Research

    Science.gov (United States)

    Harding, Luke

    2014-01-01

    This article discusses a range of current issues and future research possibilities in Communicative Language Testing (CLT) using, as its departure point, the key questions which emerged during the CLT symposium at the 2010 Language Testing Forum. The article begins with a summary of the 2010 symposium discussion in which three main issues related…

  19. Lubbock Gin Lab - Current Research and Leaf Grade Issues

    Science.gov (United States)

    This presentation was given to a group of cotton gin managers and allied industry reps. Approximately 100 attendees were in the audience. A discussion of the current research conducted at the USDA ARS CPPRU Ginning Laboratory in Lubbock, TX was given along with a discussion of leaf grade issues and ...

  20. Cheerleading and Cynicism of Effective Mentoring in Current Empirical Research

    Science.gov (United States)

    Crutcher, Paul A.; Naseem, Samina

    2016-01-01

    This article presents the results of a review of current empirical research of effective practices in teacher mentoring. Compiling literature published since 2000 in peer-reviewed journals, we examine arguments for mentoring practices to improve teacher candidate and novice teacher experiences and skills. The emergent "effective"…

  1. Current status of NADPH oxidase research in cardiovascular pharmacology

    Directory of Open Access Journals (Sweden)

    Rodiño-Janeiro BK

    2013-07-01

    Full Text Available Bruno K Rodiño-Janeiro,1,2 Beatriz Paradela-Dobarro,1 María Isabel Castiñeiras-Landeira,1 Sergio Raposeiras-Roubín,1,3 José R González-Juanatey,1,3,4 Ezequiel Álvarez1,4 1Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain; 2European Molecular Biology Laboratory, Grenoble, France; 3Cardiology Department, University Clinic Hospital of Santiago de Compostela, Santiago de Compostela, Spain; 4Medicine Department, University of Santiago de Compostela, Santiago de Compostela, Spain Abstract: The implications of reactive oxygen species in cardiovascular disease have been known for some decades. Rationally, therapeutic antioxidant strategies combating oxidative stress have been developed, but the results of clinical trials have not been as good as expected. Therefore, to move forward in the design of new therapeutic strategies for cardiovascular disease based on prevention of production of reactive oxygen species, steps must be taken on two fronts, ie, comprehension of reduction-oxidation signaling pathways and the pathophysiologic roles of reactive oxygen species, and development of new, less toxic, and more selective nicotinamide adenine dinucleotide phosphate (NADPH oxidase inhibitors, to clarify both the role of each NADPH oxidase isoform and their utility in clinical practice. In this review, we analyze the value of NADPH oxidase as a therapeutic target for cardiovascular disease and the old and new pharmacologic agents or strategies to prevent NADPH oxidase activity. Some inhibitors and different direct or indirect approaches are available. Regarding direct NADPH oxidase inhibition, the specificity of NADPH oxidase is the focus of current investigations, whereas the chemical structure-activity relationship studies of known inhibitors have provided pharmacophore models with which to search for new molecules. From a general point of view, small-molecule inhibitors are preferred because of their hydrosolubility

  2. Consciousness and working memory: Current trends and research perspectives.

    Science.gov (United States)

    Velichkovsky, Boris B

    2017-07-27

    Working memory has long been thought to be closely related to consciousness. However, recent empirical studies show that unconscious content may be maintained within working memory and that complex cognitive computations may be performed on-line. This promotes research on the exact relationships between consciousness and working memory. Current evidence for working memory being a conscious as well as an unconscious process is reviewed. Consciousness is shown to be considered a subset of working memory by major current theories of working memory. Evidence for unconscious elements in working memory is shown to come from visual masking and attentional blink paradigms, and from the studies of implicit working memory. It is concluded that more research is needed to explicate the relationship between consciousness and working memory. Future research directions regarding the relationship between consciousness and working memory are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Animal models of frailty: current applications in clinical research.

    Science.gov (United States)

    Kane, Alice E; Hilmer, Sarah N; Mach, John; Mitchell, Sarah J; de Cabo, Rafael; Howlett, Susan E

    2016-01-01

    The ethical, logistical, and biological complications of working with an older population of people inherently limits clinical studies of frailty. The recent development of animal models of frailty, and tools for assessing frailty in animal models provides an invaluable opportunity for frailty research. This review summarizes currently published animal models of frailty including the interleukin-10 knock-out mouse, the mouse frailty phenotype assessment tool, and the mouse clinical frailty index. It discusses both current and potential roles of these models in research into mechanisms of frailty, interventions to prevent/delay frailty, and the effect of frailty on outcomes. Finally, this review discusses some of the challenges and opportunities of translating research findings from animals to humans.

  4. 职业学校医学生学习动机的现状调查与研究%Investigation and research on the current situation of learning motivation of medical students in vocational schools

    Institute of Scientific and Technical Information of China (English)

    徐文兰; 张阳

    2016-01-01

    目的:为了解初中起点的职业学校医学生的学习动机和学习心理,为提高学生学习积极性提供依据,针对性采取改进措施。方法采用按专业、年级进行分层整群抽样,抽取阜阳市两所职业学校的1031名在校医学生进行调查,问卷使用黄希庭编制的学习动机问卷量表。结果学习动机内容得分从高到低依次为物质追求、小群体取向、求知进取、社会取向、个人成就、害怕失败;男生在害怕失败方面和女生具有显著差异性;中专学生求知进取动机和大专学生具有显著差异性;个人成就同年级分布具有差异,四年级各项得分均处于最高水平。结论职业学校学生学习动机更注重物质追求,满足生理需要为基础;求知进取动机不足,维持学习的动机水平较弱;对校纪校规的约束动机较弱。故应从纠正学生学习动机出发,找出对策,提高学生学习积极性。%Objective To understand the learning motivation and psychology of vocational school students started from junior high school, and to provide the basis for improving students'learning motivation, and to take measures to improve the students'learning motivation.Methods Using stratified cluster sampling method to sampling 1031 medicos from two vocational schools in Fuyang City according to specialty and grade.A questionnaire compiled by Huang Xiting was used to investigate learning motivation.Results The score of different aspects of learning motivation from high to low were material pursuit, small group orientation, learning enterprising, social orientation, personal achievement, fear of failure sequentially.The fear of failure between boys and girls has significant difference.Learning motivation between secondary school students and college students has significant difference.The distribution of personal achievement in the same grade was different. Students on the fourth grade are in the highest

  5. Investigator Bias and Theory-Ladenness in Cross-Cultural Research: Insights from Wittgenstein

    Science.gov (United States)

    Tan, Charlene

    2016-01-01

    A relatively under-explored topic in the current literature on and methods for research in the field of comparative and international education is the problem of investigator bias in cross-cultural research. This article discusses the nature of and an approach to address investigator bias in research that originates from the theory-ladenness of…

  6. Productive Research Designs for Health Education Investigations.

    Science.gov (United States)

    Green, Lawrence W.; Gordon, Nancy P.

    1982-01-01

    The problem of productivity in evaluative research is addressed from three perspectives in health education. Two perspectives are scientific, while the third is practical and deals with the implementation of evaluative research. This third perspective is illustrated through an example of a health education program about sexually transmitted…

  7. Overview of recent and current research on the TCV tokamak

    Science.gov (United States)

    S. Codathe TCV Team

    2013-10-01

    Through a diverse research programme, the Tokamak à Configuration Variable (TCV) addresses physics issues and develops tools for ITER and for the longer term goals of nuclear fusion, relying especially on its extreme plasma shaping and electron cyclotron resonance heating (ECRH) launching flexibility and preparing for an ECRH and NBI power upgrade. Localized edge heating was unexpectedly found to decrease the period and relative energy loss of edge localized modes (ELMs). Successful ELM pacing has been demonstrated by following individual ELM detection with an ECRH power cut before turning the power back up to trigger the next ELM, the duration of the cut determining the ELM period. Negative triangularity was also seen to reduce the ELM energy release. H-mode studies have focused on the L-H threshold dependence on the main ion species and on the divertor leg length. Both L- and H-modes have been explored in the snowflake configuration with emphasis on edge measurements, revealing that the heat flux to the strike points on the secondary separatrix increases as the X-points approach each other, well before they coalesce. In L-mode, a systematic scan of the auxiliary power deposition profile, with no effect on confinement, has ruled it out as the cause of confinement degradation. An ECRH power absorption observer based on transmitted stray radiation was validated for eventual polarization control. A new profile control methodology was introduced, relying on real-time modelling to supplement diagnostic information; the RAPTOR current transport code in particular has been employed for joint control of the internal inductance and central temperature. An internal inductance controller using the ohmic transformer has also been demonstrated. Fundamental investigations of neoclassical tearing mode (NTM) seed island formation by sawtooth crashes and of NTM destabilization in the absence of a sawtooth trigger were carried out. Both stabilizing and destabilizing agents

  8. Some current challenges in research on air pollution and health.

    Science.gov (United States)

    Samet, Jonathan M

    2014-01-01

    This commentary addresses some of the diverse questions of current interest with regard to the health effects of air pollution, including exposure-response relationships, toxicity of inhaled particles and risks to health, multipollutant mixtures, traffic-related pollution, accountability research, and issues with susceptibility and vulnerability. It considers the challenges posed to researchers as they attempt to provide useful evidence for policy-makers relevant to these issues. This commentary accompanies papers giving the results from the ESCALA project, a multi-city study in Latin America that has an overall goal of providing policy-relevant results. While progress has been made in improving air quality, driven by epidemiological evidence that air pollution is adversely affecting public health, the research questions have become more subtle and challenging as levels of air pollution dropped. More research is still needed, but also novel methods and approaches to address these new questions.

  9. A review on Bacopa monniera: Current research and future prospects

    Directory of Open Access Journals (Sweden)

    Gohil Kashmira

    2010-01-01

    Full Text Available In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. Lately, one of the outstandingly important medicinal plants, widely used therapeutically in the orient and becoming increasingly popular in the west is Bacopa monniera, a well-known nootropic. The present review summarizes our current knowledge of pharmacological actions, preclinical and clinical studies, major bioactives, reported mechanisms of actions, clinical efficacy, safety and the possibility of interactions of the herb with the conventional drugs. Simultaneously, research updates as well as avenues for further research are also mentioned concerning the plant.

  10. SYRUPS: COMPOSITION, TECHNOLOGY, CURRENT STATE OF RESEARCH (REVIEW

    Directory of Open Access Journals (Sweden)

    M. E. Kim

    2014-01-01

    Full Text Available The overview data for the syrups formulation, including syrups for children, with synthetic substances were represented: assortment, composition, technological approach. The advantages and disadvantages of this dosage form were described. Details considered flavoring agents and other auxiliaries (stabilizers, preservatives, thickeners comprising syrups were closely examined. The issues of current research state of syrups for children were described.

  11. Investigation of heavy current discharges with high initial gas density

    Energy Technology Data Exchange (ETDEWEB)

    Budin, A.; Bogomaz, A.; Kolikov, V.; Kuprin, A.; Leontiev, V.; Rutberg, P.; Shirokov, N. [Institute of Problems of Electrophysics of Russian Academy of Sciences, Dvortsovayanab., 18, St. Petersburg, 191065 (Russia)

    1996-05-01

    Piezoelectric pressure transducers, with noise immunity and time resolution of 0,5 {mu}s were used to measure pulse pressures of 430 MPa along the axis of an electrical discharge channel. Initial concentration of He was 2,7{center_dot}10{sup 21}cm{sup {minus}3}, dI/dt=6{center_dot}10{sup 11}A/s, and I{sub max}=560kA. Shock waves with amplitudes exceeding the pressure along the axis, were detected by a pressure transducer on the wall of the discharge chamber. Typical shock velocities were 2{center_dot}4km/s. Average pressure measurements along the discharge axis at different radii were used to estimate the current density distribution along the canal radius. The presence of the shock waves, promoting the additional hydrogen heating in the discharge chamber, has been registered during the discharge in hydrogen for I{sub max}{approximately}1MA and an initial concentration of 10{sup 21}cm{sup {minus}3}. {copyright} {ital 1996 American Institute of Physics.}

  12. Research on scheme of applying ASON to current networks

    Science.gov (United States)

    Mao, Y. F.; Li, J. R.; Deng, L. J.

    2008-10-01

    Automatically Switched Optical Network (ASON) is currently a new and hot research subject in the world. It can provide high bandwidth, high assembly flexibility, high network security and reliability, but with a low management cost. It is presented to meet the requirements for high-throughput optical access with stringent Quality of Service (QoS). But as a brand new technology, ASON can not be supported by the traditional protocol software and network equipments. And the approach to build a new ASON network on the basis of completely abandoning the traditional optical network facilities is not desirable, because it costs too much and wastes a lot of network resources can also be used. So how to apply ASON to the current networks and realize the smooth transition between the existing network and ASON has been a serious problem to many network operators. In this research, the status in quo of ASON is introduced first and then the key problems should be considered when applying ASON to current networks are discussed. Based on this, the strategies should be complied with to overcome these key problems are listed. At last, the approach to apply ASON to the current optical networks is proposed and analyzed.

  13. 14 CFR 1274.943 - Investigation of research misconduct.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Investigation of research misconduct. 1274... misconduct. Investigation of Research Misconduct May 2005 Recipients of this cooperative agreement are subject to the requirements of 14 CFR part 1275, “Investigation of Research Misconduct.”...

  14. 14 CFR 1260.40 - Investigation of research misconduct.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Investigation of research misconduct. 1260... COOPERATIVE AGREEMENTS General Provisions § 1260.40 Investigation of research misconduct. Investigation of Research Misconduct May 2005 Recipients of this grant or cooperative agreement are subject to...

  15. Animal behavioral assessments in current research of Parkinson's disease.

    Science.gov (United States)

    Asakawa, Tetsuya; Fang, Huan; Sugiyama, Kenji; Nozaki, Takao; Hong, Zhen; Yang, Yilin; Hua, Fei; Ding, Guanghong; Chao, Dongman; Fenoy, Albert J; Villarreal, Sebastian J; Onoe, Hirotaka; Suzuki, Katsuaki; Mori, Norio; Namba, Hiroki; Xia, Ying

    2016-06-01

    Parkinson's disease (PD), a neurodegenerative disorder, is traditionally classified as a movement disorder. Patients typically suffer from many motor dysfunctions. Presently, clinicians and scientists recognize that many non-motor symptoms are associated with PD. There is an increasing interest in both motor and non-motor symptoms in clinical studies on PD patients and laboratory research on animal models that imitate the pathophysiologic features and symptoms of PD patients. Therefore, appropriate behavioral assessments are extremely crucial for correctly understanding the mechanisms of PD and accurately evaluating the efficacy and safety of novel therapies. This article systematically reviews the behavioral assessments, for both motor and non-motor symptoms, in various animal models involved in current PD research. We addressed the strengths and weaknesses of these behavioral tests and their appropriate applications. Moreover, we discussed potential mechanisms behind these behavioral tests and cautioned readers against potential experimental bias. Since most of the behavioral assessments currently used for non-motor symptoms are not particularly designed for animals with PD, it is of the utmost importance to greatly improve experimental design and evaluation in PD research with animal models. Indeed, it is essential to develop specific assessments for non-motor symptoms in PD animals based on their characteristics. We concluded with a prospective view for behavioral assessments with real-time assessment with mobile internet and wearable device in future PD research.

  16. Current status of oral health research in Africa: an overview.

    Science.gov (United States)

    Kanoute, Aïda; Faye, Daouda; Bourgeois, Denis

    2012-12-01

    Research in oral health contributes effectively to decisions and strategies aimed at improving the oral health of populations. Further contributions to enhance current knowledge of oral health in Africa are required. The principal objective of this study was to produce an analysis of oral health research published from different subregions of Africa and to estimate bilateral and multilateral international cooperation in oral health research during the period 2005-2010. The PubMed database was searched for published articles on topics related to oral health in Africa. A total of 935 oral health-related articles were retrieved during April and May 2011. Publications emanating from Nigeria and South Africa accounted for a striking 68% of all oral health-related material published from Africa during the study period. Researchers from 30 different countries had participated in collaboration on at least one published article. A total of 262 journals had published at least one item examining oral health in Africa, but only 29 journals had published more than seven articles. These 29 journals accounted for 66% of all published material and induced non-African reviews (26%) and African reviews (40%). This study shows strong variation among countries in the production of articles on oral health whereby rich countries produce greater quantities of published research and poorer nations more frequently develop research partnerships with other countries. © 2012 FDI World Dental Federation.

  17. Walden Pond, Massachusetts: Environmental Setting and Current Investigations

    Science.gov (United States)

    Colman, John A.; Waldron, Marcus C.

    1998-01-01

    as plant nutrients, organic matter, and soil are leached and eroded from the surrounding watershed. This process is known as eutrophication. The term 'cultural eutrophication' refers to an accelerated form of the natural process in which extra soil and nutrients are derived from people's use of fertilizer, rerouting of surface drainage, and disposal of domestic and industrial waste. Cultural eutrophication can lead to excessive growth of aquatic plants, pond filling by decayed plants and eroded soils, reduced water clarity, and depletion of dissolved oxygen in deep water with subsequent loss of cold-water fish habitat. In order to document the longterm ecological health of Walden Pond, the U.S. Geological Survey (USGS), working in cooperation with the Massachusetts Department of Environmental Management (MDEM), is investigating factors that could contribute to cultural eutrophication of Walden. Through measurements of mass balance of nutrients and oxygen in the pond's deep water, the investigation will establish a baseline data set on Walden's trophic state, which is a measure of the pond's ability to support plant growth. The baseline data will be used to detect trends and give early warning of trophic changes or trophic response to pond remediation projects. This Fact Sheet provides background information on the environmental setting, limnological features, and cultural eutrophication of Walden Pond, and describes the joint USGS/MDEM study.

  18. CURRENT APPROACHES FOR RESEARCH OF MULTIPLE SCLEROSIS BIOMARKERS

    Directory of Open Access Journals (Sweden)

    Kolyada T.I

    2016-12-01

    Full Text Available Current data concerning features of multiple sclerosis (MS etiology, pathogenesis, clinical course and treatment of disease indicate the necessity of personalized approach to the management of MS patients. These features are the variety of possible etiological factors and mechanisms that trigger the development of MS, different courses of disease, and significant differences in treatment efficiency. Phenotypic and pathogenetic heterogeneity of MS requires, on the one hand, the stratification of patients into groups with different treatment depending on a number of criteria including genetic characteristics, disease course, stage of the pathological process, and forms of the disease. On the other hand, it requires the use of modern methods for assessment of individual risk of developing MS, its early diagnosis, evaluation and prognosis of the disease course and the treatment efficiency. This approach is based on the identification and determination of biomarkers of MS including the use of systems biology technology platforms such as genomics, proteomics, metabolomics and bioinformatics. Research and practical use of biomarkers of MS in clinical and laboratory practice requires the use of a wide range of modern medical and biological, mathematical and physicochemical methods. The group of "classical" methods used to study MS biomarkers includes physicochemical and immunological methods aimed at the selection and identification of single molecular biomarkers, as well as methods of molecular genetic analysis. This group of methods includes ELISA, western blotting, isoelectric focusing, immunohistochemical methods, flow cytometry, spectrophotometric and nephelometric methods. These techniques make it possible to carry out both qualitative and quantitative assay of molecular biomarkers. The group of "classical methods" can also include methods based on polymerase chain reaction (including multiplex and allele-specific PCR and genome sequencing

  19. Gender relations and health research: a review of current practices

    Directory of Open Access Journals (Sweden)

    Bottorff Joan L

    2011-12-01

    Full Text Available Abstract Introduction The importance of gender in understanding health practices and illness experiences is increasingly recognized, and key to this work is a better understanding of the application of gender relations. The influence of masculinities and femininities, and the interplay within and between them manifests within relations and interactions among couples, family members and peers to influence health behaviours and outcomes. Methods To explore how conceptualizations of gender relations have been integrated in health research a scoping review of the existing literature was conducted. The key terms gender relations, gender interactions, relations gender, partner communication, femininities and masculinities were used to search online databases. Results Through analysis of this literature we identified two main ways gender relations were integrated in health research: a as emergent findings; and b as a basis for research design. In the latter, gender relations are included in conceptual frameworks, guide data collection and are used to direct data analysis. Conclusions Current uses of gender relations are typically positioned within intimate heterosexual couples whereby single narratives (i.e., either men or women are used to explore the influence and/or impact of intimate partner gender relations on health and illness issues. Recommendations for advancing gender relations and health research are discussed. This research has the potential to reduce gender inequities in health.

  20. Current safety practices in nano-research laboratories in China.

    Science.gov (United States)

    Zhang, Can; Zhang, Jing; Wang, Guoyu

    2014-06-01

    China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

  1. Current frontiers and future directions of telecoupling research

    Science.gov (United States)

    Liu, J.

    2016-12-01

    The world has been increasingly interconnected over long distances though processes such as international trade, migration, telecommunication, and disease spread. However, previous studies often focused on socioeconomic or environmental issues of distant processes. While these studies have generated useful information for individual disciplines, integrating socioeconomic and environmental information is essential for holistic understanding of complex global challenges and unbiased decision making to address the challenges. To advance integrated research, the framework of telecoupling (socioeconomic and environmental interactions over distances) has been developed to explicitly address both socioeconomic and environmental issues simultaneously. Although the framework is relatively new, it has already been applied to tackle a variety of globally important issues, such as food security, water resources, energy sustainability, land use, international trade (e.g., food, forest products, energy, wildlife, industrial products), species invasion, investment, ecosystem services, conservation, information dissemination, and tourism. These applications have identified many important research gaps (e.g. spillover systems) and hidden linkages (e.g. feedbacks) among distant areas of the world with profound implications for sustainable development, ecosystem health, and human well-being. While working with telecoupling presents more challenges than focusing only on disciplinary issues, support from funding agencies has helped accelerate research on telecoupling and more efforts are being aimed at framework quantification and operationalization. The presenter will provide an overview of the current frontiers, discuss future research directions, and highlight emerging opportunities and challenges in telecoupling research and governance.

  2. Current research in child and adolescent bipolar disorder.

    Science.gov (United States)

    Demeter, Christine A; Townsend, Lisa D; Wilson, Michael; Findling, Robert L

    2008-01-01

    Although recently more research has considered children with bipolar disorder than in the past, much controversy still surrounds the validity of the diagnosis. Furthermore, questions remain as to whether or not childhood expressions of bipolarity are continuous with adult manifestations of the illness. In order to advance current knowledge of bipolar disorders in children, researchers have begun to conduct phenomenological, longitudinal, treatment, and neuroimaging studies in youths who exhibit symptoms of bipolar illness, as well as offspring of parents with bipolar disorders. Regardless of the differences between research groups regarding how bipolar disorder in children is defined, it is agreed that pediatric bipolarity is a serious and pernicious illness. With early intervention during the period of time in which youths are exhibiting subsyndromal symptoms of pediatric bipolarity, it appears that the progression of the illness to the more malignant manifestation of the disorder may be avoided. This paper will review what is currently known and what still is left to learn about clinically salient topics that pertain to bipolar disorder in children and adolescents.

  3. Survey of biomass gasification. Volume III. Current technology and research

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-04-01

    This survey of biomass gasification was written to aid the Department of Energy and the Solar Energy Research Institute Biological and Chemical Conversion Branch in determining the areas of gasification that are ready for commercialization now and those areas in which further research and development will be most productive. Chapter 8 is a survey of gasifier types. Chapter 9 consists of a directory of current manufacturers of gasifiers and gasifier development programs. Chapter 10 is a sampling of current gasification R and D programs and their unique features. Chapter 11 compares air gasification for the conversion of existing gas/oil boiler systems to biomass feedstocks with the price of installing new biomass combustion equipment. Chapter 12 treats gas conditioning as a necessary adjunct to all but close-coupled gasifiers, in which the product is promptly burned. Chapter 13 evaluates, technically and economically, synthesis-gas processes for conversion to methanol, ammonia, gasoline, or methane. Chapter 14 compiles a number of comments that have been assembled from various members of the gasifier community as to possible roles of the government in accelerating the development of gasifier technology and commercialization. Chapter 15 includes recommendations for future gasification research and development.

  4. Current status of research and related activities in NAA application

    Energy Technology Data Exchange (ETDEWEB)

    Ab. Khalik bin Haji Wood [Malaysia Institute for Nuclear Technology Research, Bangi, Selangor (Malaysia)

    1999-10-01

    Current activities of Analytical Chemistry Group of MINT (Malaysia Institute for Nuclear Technology Research) laboratory for elemental analysis of trace amounts in environmental samples such as air particulate matter (on air filter), soils/sediments, water, flora/fauna, oil sludge/waste sludge, and tailing/blasting slag and others, utilizing particularly NAA (Neutron Activation Analysis) method are reviewed. The laboratory participates in the IAEA-organized Interlaboratory Comparison Studies to ensure the analytical system. Other activities include analytical chemistry services with ICP-mass spectrometry and GC/GCMS to compliment the NAA and, moreover, air and marine pollution studies with participation in the UNDP/RCA/IAEA project. (S. Ohno)

  5. Investigation and analysis of the current cognition status of nursing staff who attended a training course on qualitative research in Zhejiang Province%浙江省某学习班护理人员质性研究认知现状调查与分析

    Institute of Scientific and Technical Information of China (English)

    阮佳音; 周云仙

    2015-01-01

    目的:了解护理人员质性研究认知现状,为相关培训提供依据。方法采用自制问卷对2014年浙江省护理质性研究学习班111名学员进行调查。结果100名护理人员中有60%的护理人员对质性研究不了解,仅15%的护理人员做过质性研究。有所接触的质性研究方法以现象学(4%)和描述性质性研究(10%)为主。获取质性研究知识主要途径为文献期刊(51%)。护理人员对10道质性研究认知单选题正确率均低于80%。结论护理人员质性研究认知水平亟待提高,需给予切实的针对性培训。%Objective To investigate the current cognition status of nursing staff on qualitative research, so as to provide information for related training courses. Methods A self-designed questionnaire was used to survey 111 members who attended the nursing qualitative research training course in Zhejiang Province in 2014. Results Among 100 respondents,60% knew little about qualitative research, only 15% respondents had done qualitative research before. The main qualitative research methods that respondents had heard of were phenomenology (4%) and descriptive qualitative method(10%). Literatures (51%) was the main way to get knowledge on qualitative research. Conclusions The cognition level of nursing staff on qualitative research needs to be improved urgently by offering more targeted training courses.

  6. On Unsaturated Soil Mechanics - Personal Views on Current Research

    Science.gov (United States)

    Pande, G. N.; Pietruszczak, S.

    2015-09-01

    This paper presents the authors' personal views on current research being conducted by various research groups around the world in the broad area of mechanics of unsaturated geomaterials in general and soils in particular. The topic is of interest to a wide spectrum of scientists and engineers working in diverse areas such as geology and geophysics, powder technology, agricultural, petroleum, chemical, geotechnical, civil, environmental and nuclear engineering. Even if we restrict ourselves to civil, geotechnical and environmental engineering, it is noted that a plethora of hypotheses as well as a number of empirical and semi-empirical relations have been introduced for describing the mechanics of unsaturated porous media. However, many of these proposed advances as well as methods of testing may lack sound theoretical basis.

  7. Current Research and Management of Ovarian Cancer in China

    Institute of Scientific and Technical Information of China (English)

    GUMeijiao; SHIWei

    2002-01-01

    Ovarian cancer is ne of the most lethal malignant tumors in China,represents the third most common cancer after cervical cancer and endometrial cancer,and the first leading cause of death from hynaecological cancers.Due to the lack of effective screening strategies and the absence of symptoms in early-stage of disease,over 70% of patients present at an advanced stage.Despite the advances in surgical techniques and conventional chemotheraphy,the prognosis of ovarian cancer has not been improved significantly,and indeed the long-term survival for patients with advanced disease does not exceed 20%.The aetiology of ovarian cancer temains poorly understood.In China,the major focus of research is to clarify the mechanism underlying ovarian cancer,develop more effective life-saving diagnostic and therapeutic measures,and undertake more population-based studies.This article summarizes current research,diagnosis and management of ovarian cancer in China.

  8. Bulk Glassy Alloys: Historical Development and Current Research

    Directory of Open Access Journals (Sweden)

    Akihisa Inoue

    2015-06-01

    Full Text Available This paper reviews the development of current research in bulk glassy alloys by focusing on the trigger point for the synthesis of the first bulk glassy alloys by the conventional mold casting method. This review covers the background, discovery, characteristics, and applications of bulk glassy alloys, as well as recent topics regarding them. Applications of bulk glassy alloys have been expanding, particularly for Fe-based bulk glassy alloys, due to their unique properties, high glass-forming ability, and low cost. In the near future, the engineering importance of bulk glassy alloys is expected to increase steadily, and continuous interest in these novel metallic materials for basic science research is anticipated.

  9. On Unsaturated Soil Mechanics – Personal Views on Current Research

    Directory of Open Access Journals (Sweden)

    Pande G.N.

    2015-09-01

    Full Text Available This paper presents the authors’ personal views on current research being conducted by various research groups around the world in the broad area of mechanics of unsaturated geomaterials in general and soils in particular. The topic is of interest to a wide spectrum of scientists and engineers working in diverse areas such as geology and geophysics, powder technology, agricultural, petroleum, chemical, geotechnical, civil, environmental and nuclear engineering. Even if we restrict ourselves to civil, geotechnical and environmental engineering, it is noted that a plethora of hypotheses as well as a number of empirical and semi-empirical relations have been introduced for describing the mechanics of unsaturated porous media. However, many of these proposed advances as well as methods of testing may lack sound theoretical basis.

  10. Astrobites: Engaging Undergraduate Science Majors with Current Astrophysical Research

    Science.gov (United States)

    Zevin, Michael; Astrobites

    2017-01-01

    Astrobites is a graduate-student organization that publishes an online astrophysical literature blog (astrobites.com). The purpose of the site is to make current astrophysical research accessible to and exciting for undergraduate physical science majors and astronomy enthusiasts, and the site now hosts an archive of over 1300 posts summarizing recent astrophysical research. In addition, Astrobites presents posts on career guidance, practical 'how-to' articles, conference summaries, and astronomy news. Astrobites has an average of more than 1000 pageviews per day and reaches not only its target audience of undergraduates, but also graduate students and professionals within astronomy, astronomy enthusiasts, and educators. As we enter our seventh year of successful blogging, we share here the most up-to-date summary of our organization, readership, and growth.

  11. Viewpoint on the current status of researches on sepsis

    Directory of Open Access Journals (Sweden)

    Zheng-guo WANG

    2012-11-01

    Full Text Available Sepsis is a common complication after severe trauma and burn, and also one of the main causes of death. Recently, although some new progresses were seen in antibiotic therapy, the mortality of sepsis is still on the rise, and the death rate as a result of sepsis is higher than a total of that of prostate cancer, breast cancer and AIDS. Therefore, sepsis has obviously become one of the serious ailments threatening human health. The present paper introduced the international definition of sepsis, severe sepsis and septic shock, the current researches on diagnosis and therapy, and proposed that we should not only pay attention to pathogenesis and treatment, but also to sepsis prevention in sepsis researches, and we should try to find out the breakthrough in the interaction and dynamic balance between human being and pathogenic factors. Researches on the strategies to revert strong toxicity of infectious agents to non-toxic or weak pathogenic factors, and to conduct further research concerning biological characteristics of microorganisms and mechanism of drug resistance in order to render them to lose the drug resistance ability, or to increase its sensitivity to the drugs. The above suggested approaches might form the future strategies for preventing and controlling sepsis.

  12. First Language Transfer in Second Language Writing: An Examination of Current Research

    Science.gov (United States)

    Karim, Khaled; Nassaji, Hossein

    2013-01-01

    First language (L1) transfer has been a key issue in the field of applied linguistics, second language acquisition (SLA), and language pedagogy for almost a century. Its importance, however, has been re-evaluated several times within the last few decades. The aim of this paper is to examine current research that has investigated the role of L1…

  13. Support for international agricultural research: current status and future challenges.

    Science.gov (United States)

    Zeigler, Robert S; Mohanty, Samarendu

    2010-11-30

    The success of the first Green Revolution in the form of abundant food supplies and low prices over the past two decades has diverted the world's attention from agriculture to other pressing issues. This has resulted in lower support for the agricultural research work primarily undertaken by the 15 research centers of the Consultative Group on International Agricultural Research (CGIAR). The total support in real dollars for most of the last three decades has been more or less flat although the number of centers increased from 4 to 15. However, since 2000, the funding situation has improved for the CGIAR centers, with almost all the increase coming from grants earmarked for specific research projects. Even for some centers such as the International Rice Research Institute (IRRI), the downward trend continued as late as 2006 with the budget in real dollars reaching the 1978 level of support. The recent food crisis has renewed the call for a second Green Revolution by revitalizing yield growth to feed the world in the face of growing population and a shrinking land base for agricultural use. The slowdown in yield growth because of decades of neglect in agricultural research and infrastructure development has been identified as the underlying reason for the recent food crisis. For the second Green Revolution to be successful, the CGIAR centers will have to play a complex role by expanding productivity in a sustainable manner with fewer resources. Thus, it is crucial to examine the current structure of support for the CGIAR centers and identify the challenges ahead in terms of source and end use of funds for the success of the second Green Revolution. The objective of this paper is to provide a historical perspective on the support to the CGIAR centers and to examine the current status of funding, in particular, the role of project-specific grants in rebuilding capacity of these centers. The paper will also discuss the nature of the support (unrestricted vs. project

  14. Livestock in biomedical research: history, current status and future prospective.

    Science.gov (United States)

    Polejaeva, Irina A; Rutigliano, Heloisa M; Wells, Kevin D

    2016-01-01

    Livestock models have contributed significantly to biomedical and surgical advances. Their contribution is particularly prominent in the areas of physiology and assisted reproductive technologies, including understanding developmental processes and disorders, from ancient to modern times. Over the past 25 years, biomedical research that traditionally embraced a diverse species approach shifted to a small number of model species (e.g. mice and rats). The initial reasons for focusing the main efforts on the mouse were the availability of murine embryonic stem cells (ESCs) and genome sequence data. This powerful combination allowed for precise manipulation of the mouse genome (knockouts, knockins, transcriptional switches etc.) leading to ground-breaking discoveries on gene functions and regulation, and their role in health and disease. Despite the enormous contribution to biomedical research, mouse models have some major limitations. Their substantial differences compared with humans in body and organ size, lifespan and inbreeding result in pronounced metabolic, physiological and behavioural differences. Comparative studies of strategically chosen domestic species can complement mouse research and yield more rigorous findings. Because genome sequence and gene manipulation tools are now available for farm animals (cattle, pigs, sheep and goats), a larger number of livestock genetically engineered (GE) models will be accessible for biomedical research. This paper discusses the use of cattle, goats, sheep and pigs in biomedical research, provides an overview of transgenic technology in farm animals and highlights some of the beneficial characteristics of large animal models of human disease compared with the mouse. In addition, status and origin of current regulation of GE biomedical models is also reviewed.

  15. INVESTIGATION OF MICROPROCESSOR TRANSFORMER CURRENT PROTECTION IN SHORT CIRCUIT FAULT MODES

    Directory of Open Access Journals (Sweden)

    M. S. Loman

    2014-01-01

    Full Text Available The paper presents an investigation on transformer current protection with blocking against magnetizing inrush current in short circuit fault modes. It has been shown that the proposed magnetizing in-rush current blocking algorithm can be implemented in microprocessor current protections of transformers.

  16. Precision viticulture in Brazil: Current research status on wine grape

    Directory of Open Access Journals (Sweden)

    Miele Alberto

    2014-01-01

    Full Text Available Technologies associated to precision viticulture (PV are not currently used by Brazilian growers. To overcome this situation, a research is being carried out since 2011 in a vineyard of Merlot using a wide range of PV technologies. During this period, several PV research activities were performed which will be concluded in a couple of years. Therefore, final results depend on further variable evaluation which should be done by means of geostatistic, Geographic Information Systems and Principal Component Analysis. This paper briefly presents a series of methodological procedures used in different ways to attain the objective of this research project. In the sequence, it describes one final result and nine partial ones. Morphological and physicochemical analyses of soil showed that the vineyards are established on three taxonomic classes of soil – Argissolo, Cambissolo and Neossolo −, which are formed by ten mapping units. The partial results are mainly related to the utilization of GIS, modeling and must and wine composition of five mapping units; however they show results of only one year. With the complete set of analyses, data should be spatialized and maps prepared. Then, it will be possible to recommend different practices to each soil type and to aid oenologists to direct wines to a specific quality pattern.

  17. Current Status and Research into Overcoming Limitations of Capsule Endoscopy.

    Science.gov (United States)

    Kwack, Won Gun; Lim, Yun Jeong

    2016-01-01

    Endoscopic investigation has a critical role in the diagnosis and treatment of gastrointestinal (GI) diseases. Since 2001, capsule endoscopy (CE) has been available for small-bowel exploration and is under continuous development. During the past decade, CE has achieved impressive improvements in areas such as miniaturization, resolution, and battery life. As a result, CE is currently a first-line tool for the investigation of the small bowel in obscure gastrointestinal bleeding and is a useful alternative to wired enteroscopy. Nevertheless, CE still has several limitations, such as incomplete examination and limited diagnostic and therapeutic capabilities. To resolve these problems, many groups have suggested several models (e.g., controlled CO2 insufflation system, magnetic navigation system, mobile robotic platform, tagging and biopsy equipment, and targeted drug-delivery system), which are in development. In the near future, new technological advances will improve the capabilities of CE and broaden its spectrum of applications not only for the small bowel but also for the colon, stomach, and esophagus. The purpose of this review is to introduce the current status of CE and to review the ongoing development of solutions to address its limitations.

  18. Incredible Years parenting interventions: current effectiveness research and future directions.

    Science.gov (United States)

    Gardner, Frances; Leijten, Patty

    2017-06-01

    The Incredible Years parenting intervention is a social learning theory-based programme for reducing children's conduct problems. Dozens of randomized trials, many by independent investigators, find consistent effects of Incredible Years on children's conduct problems across multiple countries and settings. However, in common with other interventions, these average effects hide much variability in the responses of individual children and families. Innovative moderator research is needed to enhance scientific understanding of why individual children and parents respond differently to intervention. Additionally, research is needed to test whether there are ways to make Incredible Years more effective and accessible for families and service providers, especially in low resource settings, by developing innovative delivery systems using new media, and by systematically testing for essential components of parenting interventions. Copyright © 2017. Published by Elsevier Ltd.

  19. Translational research in infectious disease: current paradigms and challenges ahead.

    Science.gov (United States)

    Fontana, Judith M; Alexander, Elizabeth; Salvatore, Mirella

    2012-06-01

    In recent years, the biomedical community has witnessed a rapid scientific and technologic evolution after the development and refinement of high-throughput methodologies. Concurrently and consequentially, the scientific perspective has changed from the reductionist approach of meticulously analyzing the fine details of a single component of biology to the "holistic" approach of broadmindedly examining the globally interacting elements of biological systems. The emergence of this new way of thinking has brought about a scientific revolution in which genomics, proteomics, metabolomics, and other "omics" have become the predominant tools by which large amounts of data are amassed, analyzed, and applied to complex questions of biology that were previously unsolvable. This enormous transformation of basic science research and the ensuing plethora of promising data, especially in the realm of human health and disease, have unfortunately not been followed by a parallel increase in the clinical application of this information. On the contrary, the number of new potential drugs in development has been decreasing steadily, suggesting the existence of roadblocks that prevent the translation of promising research into medically relevant therapeutic or diagnostic application. In this article, we will review, in a noninclusive fashion, several recent scientific advancements in the field of translational research, with a specific focus on how they relate to infectious disease. We will also present a current picture of the limitations and challenges that exist for translational research, as well as ways that have been proposed by the National Institutes of Health to improve the state of this field. Copyright © 2012 Mosby, Inc. All rights reserved.

  20. Current status of silicon materials research for photovoltaic applications

    Energy Technology Data Exchange (ETDEWEB)

    Ciszek, T F

    1985-04-01

    The desire for high solar cell efficiencies has been a strong factor in determining the course of recent silicon crystal growth research efforts for photovoltaics. This review, therefore, focuses on single-crystal, dislocation-free ingot growth methods (Czochralski growth, float zoning, and cold crucible growth) and on sheet growth technologies, generally multicrystalline, that have achieved moderately high (>13.5%) laboratory-scale efficiencies. These include dendritic web growth, growth from capillary dies, edge-supported pulling, ribbon-against-drop growth, and a recent technique termed crucible-free horizontal growth. Silicon ribbon crystals provide a favorable geometry and require no wafering, but they contain defects that limit solar cell performance. Growth processes, their current status, and cell efficiencies are discussed. Silicon material process steps before and after crystal growth are described, and the advantages of silicon are presented.

  1. Current Debates in Corporate Social Responsibility: An Agenda for Research

    Directory of Open Access Journals (Sweden)

    David Crowther

    2007-06-01

    Full Text Available Corporate Social Responsibility (CSR has a particular prominence at this point in time, featuring heavily in the discourses of both academe and business. The understanding of what is meant by CSR continues to evolve as a consensus is reached. Nevertheless some important debates continue – or are commencing – which need to be resolved. It is the purpose of this paper to highlight these as some of the current debates within the CSR community – and hence form a significant part of an agenda for research in the area. Specifically we focus upon three key areas for the management of business, namely setting standards for reporting, identifying and implementing sustainable practice, and the management of risk.

  2. Current Research Status of KHNP for Site Risk

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Kyemin; Jeon, Ho-Jun; Bahng, Ki-In; Na, Jang-Hwan [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    In Korea, by the geographical characteristics, many Nuclear Power Plants (NPPs) have been constructed and operated at a single site. This is above average level or number of plants per site in the world. For this reason, the public concerns for the safety of nuclear facilities increased after Fukushima Daiichi accident. As a result, comprehensive risk assessment and management for the site which have multi-unit NPPs were strongly asked. Currently, to solve it, many researches and projects has carried out by various Korean companies, research centers, and regulatory authorities. In this paper, R and D plans of KHNP for multi-unit risk were summarized. Firstly, the needs of multi-unit PSA were reviewed. R and D activities and plans of KHNP were summarized in the last part. In this paper, we summarized the R and D plans of KHNP for assessing the multi-unit risk. Currently, multi-unit risk or multi-unit PSA are important and practical issues in both nuclear industry and national energy policy. After Fukushima accident, several countries stopped the construction and the operation of NPPs, other countries which is maintaining the NPPs are being strongly asked to assess the risk for multi-unit NPPs at the same site. Because of Korean geographical characteristics, the number of NPPs which are above average level or number of plants per site in the world is being constructed and operated at a single site. The population density nearby each site is considered to be higher than that of other countries.

  3. [Video game and internet addiction. The current state of research].

    Science.gov (United States)

    Rehbein, F; Mößle, T; Arnaud, N; Rumpf, H-J

    2013-05-01

    The use of interactive screen media is widespread and for some users leads to pathological symptoms that are phenomenologically similar to signs of addictive disorders. Addictive use of computer games and other Internet applications, such as social media can be distinguished. In the past standard criteria to classify this new disorder were lacking. In DSM-5, nine criteria are proposed for diagnosing Internet gaming disorder. The focus is currently on video games as most studies have been done in this field. Prevalence estimations are difficult to interpret due to the lack of standard diagnostic measures and result in a range of the frequency of Internet addiction between 1 % and 4.2 % in the general German population. Rates are higher in younger individuals. For computer game addiction prevalence rates between 0.9 % and 1.7  % can be found in adolescents. Despite substantial comorbidity among those affected current research points to addictive media use as a stand-alone disorder.

  4. Collaborative Research in Childhood Cancer Survivorship: The Current Landscape.

    Science.gov (United States)

    Bhatia, Smita; Armenian, Saro H; Armstrong, Gregory T; van Dulmen-den Broeder, Eline; Hawkins, Michael M; Kremer, Leontien C M; Kuehni, Claudia E; Olsen, Jørgen H; Robison, Leslie L; Hudson, Melissa M

    2015-09-20

    Survivors of childhood cancer carry a substantial burden of morbidity and are at increased risk for premature death. Furthermore, clear associations exist between specific therapeutic exposures and the risk for a variety of long-term complications. The entire landscape of health issues encountered for decades after successful completion of treatment is currently being explored in various collaborative research settings. These settings include large population-based or multi-institutional cohorts and single-institution studies. The ascertainment of outcomes has depended on self-reporting, linkage to registries, or clinical assessments. Survivorship research in the cooperative group setting, such as the Children's Oncology Group, has leveraged the clinical trials infrastructure to explore the molecular underpinnings of treatment-related adverse events, and to understand specific complications in the setting of randomized risk-reduction strategies. This review highlights the salient findings from these large collaborative initiatives, emphasizing the need for life-long follow-up of survivors of childhood cancer, and describing the development of several guidelines and efforts toward harmonization. Finally, the review reinforces the need to identify populations at highest risk, facilitating the development of risk prediction models that would allow for targeted interventions across the entire trajectory of survivorship.

  5. FES in Europe and Beyond: Current Translational Research

    Science.gov (United States)

    Coste, Christine Azevedo; Mayr, Winfried; Bijak, Manfred; Musarò, Antonio; Carraro, Ugo

    2016-01-01

    Capacity of adult neural and muscle tissues to respond to external Electrical Stimulation (ES) is the biological basis for the development and implementation of mobility impairment physiotherapy protocols and of related assistive technologies, e.g, Functional Electrical Stimulation (FES). All body tissues, however, respond to electrical stimulation and, indeed, the most successful application of FES is electrical stimulation of the heart to revert or limit effects of arrhythmias (Pace-makers and Defibrillators). Here, we list and discuss results of FES current research activities, in particular those presented at 2016 Meetings: the PaduaMuscleDays, the Italian Institute of Myology Meeting, the 20th International Functional Electrical Stimulation Society (IFESS) conference held in Montpellier and the Vienna Workshop on FES. Several papers were recently e-published in the European Journal of Translational Myology as reports of meeting presentations. All the events and publications clearly show that FES research in Europe and beyond is alive and promisses translation of results into clinical management of a very large population of persons with deficiencies. PMID:28078074

  6. FES in Europe and beyond: Current Translational Research

    Directory of Open Access Journals (Sweden)

    Christine Azevedo Coste

    2016-12-01

    Full Text Available Capacity of adult neural and muscle tissues to respond to external Electrical Stimulation (ES is the biological basis for the development and implementation of mobility impairment physiotherapy protocols and of related assistive technologies, e.g, Functional Electrical Stimulation (FES. All body tissues, however, respond to electrical stimulation and, indeed, the most successful application of FES is electrical stimulation of the heart to revert or limit effects of arrhythmias (Pace-makers and Defibrillators. Here, we list and discuss results of FES current research activities, in particular those presented at 2016 Meetings: the PaduaMuscleDays, the Italian Institute of Myology Meeting, the 20th International Functional Electrical Stimulation Society (IFESS conference held in Montpellier and the Vienna Workshop on FES. Several papers were recently e-published in the European Journal of Translational Myology as reports of meeting presentations. All the events and publications clearly show that FES research in Europe and beyond is alive and promisses translation of results into clinical management of a very large population of persons with deficiencies.

  7. Human behavioral assessments in current research of Parkinson's disease.

    Science.gov (United States)

    Asakawa, Tetsuya; Fang, Huan; Sugiyama, Kenji; Nozaki, Takao; Kobayashi, Susumu; Hong, Zhen; Suzuki, Katsuaki; Mori, Norio; Yang, Yilin; Hua, Fei; Ding, Guanghong; Wen, Guoqiang; Namba, Hiroki; Xia, Ying

    2016-09-01

    Parkinson's disease (PD) is traditionally classified as a movement disorder because patients mainly complain about motor symptoms. Recently, non-motor symptoms of PD have been recognized by clinicians and scientists as early signs of PD, and they are detrimental factors in the quality of life in advanced PD patients. It is crucial to comprehensively understand the essence of behavioral assessments, from the simplest measurement of certain symptoms to complex neuropsychological tasks. We have recently reviewed behavioral assessments in PD research with animal models (Asakawa et al., 2016). As a companion volume, this article will systematically review the behavioral assessments of motor and non-motor PD symptoms of human patients in current research. The major aims of this article are: (1) promoting a comparative understanding of various behavioral assessments in terms of the principle and measuring indexes; (2) addressing the major strengths and weaknesses of these behavioral assessments for a better selection of tasks/tests in order to avoid biased conclusions due to inappropriate assessments; and (3) presenting new concepts regarding the development of wearable devices and mobile internet in future assessments. In conclusion we emphasize the importance of improving the assessments for non-motor symptoms because of their complex and unique mechanisms in human PD brains.

  8. Public health services and systems research: current state of finance research.

    Science.gov (United States)

    Ingram, Richard C; Bernet, Patrick M; Costich, Julia F

    2012-11-01

    There is a growing recognition that the US public health system should strive for efficiency-that it should determine the optimal ways to utilize limited resources to improve and protect public health. The field of public health finance research is a critical part of efforts to understand the most efficient ways to use resources. This article discusses the current state of public health finance research through a review of public health finance literature, chronicles important lessons learned from public health finance research to date, discusses the challenges faced by those seeking to conduct financial research on the public health system, and discusses the role of public health finance research in relation to the broader endeavor of Public Health Services and Systems Research.

  9. An Investigation on the Current Situation of Management Information Systems Discipline in Turkey

    Directory of Open Access Journals (Sweden)

    Serdar YARLIKAŞ

    2015-09-01

    Full Text Available The purpose of this research is to investigate the development of management information systems field by evaluating the theses conducted at universities in Turkey in the departments of management information systems and science of management information systems. First, this study aims to determine the distribution of the theses in terms of years, subjects and the research methods used. Another purpose of this study was to determine which of the related disciplines of management information systems are used most in the theses. In addition, as a result of the study, the compatibility degree between the theses written and the courses taught in the graduate programs of management information systems were determined. In this research, content analysis method is used. Through this method, each of the theses was evaluated with a 10-question ‘thesis evaluation question set' constructed towards the purpose of the study. Through this evaluation, the current situation of the field was determined. It was observed that the number of doctoral theses associated with the field was less. Using the combination of qualitative and quantitative techniques most in the theses denoted that the interdisciplinary approaches were adopted in the theses associated with management information systems. It was observed that the literature analysis and survey techniques were the most studied research methods in the theses. Besides, statistical techniques were used highly in the theses. As a result of this study, it was concluded that out of the associated disciplines of management information systems, management science, computer science and statistics disciplines were more associated with the investigated theses. When the study results were evaluated as a whole, it was seen that significant progress was made in the discipline of management information systems compared to the early 2000s.

  10. Munchausen by Internet: Current Research and Future Directions

    Science.gov (United States)

    Taylor, Jacqui

    2012-01-01

    Background The Internet has revolutionized the health world, enabling self-diagnosis and online support to take place irrespective of time or location. Alongside the positive aspects for an individual’s health from making use of the Internet, debate has intensified on how the increasing use of Web technology might have a negative impact on patients, caregivers, and practitioners. One such negative health-related behavior is Munchausen by Internet. Objective Munchausen by Internet occurs when medically well individuals fake recognized illnesses in virtual environments, such as online support groups. This paper focuses on the aspect of Munchausen by Internet in which individuals actively seek to disrupt groups for their own satisfaction, which has not yet been associated with the wider phenomena of Internet trolls (users who post with the intention of annoying someone or disrupting an online environment). Methods A wide-ranging review was conducted to investigate the causes and impacts of online identity deception and Munchausen by Internet drawing on academic research and case studies reported online and in the media. Results The limited research relating to motivation, opportunity, detection, effects, and consequences of Munchausen by Internet is highlighted and it is formally linked to aspects of trolling. Case studies are used to illustrate the phenomenon. What is particularly worrying is the ease with which the deception can be carried out online, the difficulty in detection, and the damaging impact and potential danger to isolated victims. Conclusions We suggest ways to deal with Munchausen by Internet and provide advice for health group facilitators. We also propose that Munchausen by Internet and Munchausen by Internet trolling should be formally acknowledged in a revised version of the Diagnostic and Statistical Manual DSM-5. This will assist in effectively identifying and minimizing the growth of this behavior as more people seek reassurance and support

  11. An investigation of the role of current and future remote sensing data systems in numerical meteorology

    Science.gov (United States)

    Diak, George R.; Smith, William L.

    1993-01-01

    The goals of this research endeavor have been to develop a flexible and relatively complete framework for the investigation of current and future satellite data sources in numerical meteorology. In order to realistically model how satellite information might be used for these purposes, it is necessary that Observing System Simulation Experiments (OSSEs) be as complete as possible. It is therefore desirable that these experiments simulate in entirety the sequence of steps involved in bringing satellite information from the radiance level through product retrieval to a realistic analysis and forecast sequence. In this project we have worked to make this sequence realistic by synthesizing raw satellite data from surrogate atmospheres, deriving satellite products from these data and subsequently producing analyses and forecasts using the retrieved products. The accomplishments made in 1991 are presented. The emphasis was on examining atmospheric soundings and microphysical products which we expect to produce with the launch of the Advanced Microwave Sounding Unit (AMSU), slated for flight in mid 1994.

  12. The investigation of reverse traction current influence on tone track circuit modes

    Directory of Open Access Journals (Sweden)

    E.I.Jasсhuk

    2012-12-01

    Full Text Available Introduction: With the introduction of high-speed traffic there is an increased consumption of traction current by new types of rolling stock. This issue is important, as high levels of traction currents can have not only prevents, but also a dangerous impact on the equipment of railway automation devices. It is necessary to investigate the propagation of traction currents and potentials along the rails. Objective: Investigate the propagation of traction currents and potentials along the rails, the determination of critical currents, which not executed tone track circuits modes. Methods: In order to investigate the mathematical model, and the method of calculation tone track circuits modes was used. Results: By means of mathematical model, which includes being several rolling-stocks at the feeder zone, different rail resistance and isolation, the diagrams of currents and potentials propagations for DC and AC electric traction have been obtained. A comparative analysis of the experimental data and the results of the investigation has been realized. Based on received levels of reverse traction current their influence on track circuit modes has been investigated. Conclusions: The reverse traction current level near the substation and rolling-stock can be more than 600A. Great reverse traction current levels have an influence on tonal track circuit functioning, namely normal and shunt modes. When the traction current arrives 200 A there is a reduction criteria of tonal track circuits.

  13. Current Research Therapeutic Strategies for Alzheimer's Disease Treatment

    Science.gov (United States)

    Folch, Jaume; Petrov, Dmitry; Ettcheto, Miren; Abad, Sonia; Sánchez-López, Elena; García, M. Luisa; Olloquequi, Jordi; Beas-Zarate, Carlos; Auladell, Carme; Camins, Antoni

    2016-01-01

    Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing down disease progression. In recent years the main focus of research on novel pharmacotherapies was based on the amyloidogenic hypothesis of AD, which posits that the beta amyloid (Aβ) peptide is chiefly responsible for cognitive impairment and neuronal death. The goal of such treatments is (a) to reduce Aβ production through the inhibition of β and γ secretase enzymes and (b) to promote dissolution of existing cerebral Aβ plaques. However, this approach has proven to be only modestly effective. Recent studies suggest an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse. Aβ oligomers may cause aberrant N-methyl-D-aspartate receptor (NMDAR) activation postsynaptically by forming complexes with the cell-surface prion protein (PrPC). PrPC is enriched at the neuronal postsynaptic density, where it interacts with Fyn tyrosine kinase. Fyn activation occurs when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5). Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease. PMID:26881137

  14. Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

    Directory of Open Access Journals (Sweden)

    Jaume Folch

    2016-01-01

    Full Text Available Alzheimer’s disease (AD currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing down disease progression. In recent years the main focus of research on novel pharmacotherapies was based on the amyloidogenic hypothesis of AD, which posits that the beta amyloid (Aβ peptide is chiefly responsible for cognitive impairment and neuronal death. The goal of such treatments is (a to reduce Aβ production through the inhibition of β and γ secretase enzymes and (b to promote dissolution of existing cerebral Aβ plaques. However, this approach has proven to be only modestly effective. Recent studies suggest an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse. Aβ oligomers may cause aberrant N-methyl-D-aspartate receptor (NMDAR activation postsynaptically by forming complexes with the cell-surface prion protein (PrPC. PrPC is enriched at the neuronal postsynaptic density, where it interacts with Fyn tyrosine kinase. Fyn activation occurs when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5. Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease.

  15. Current status of auditory aging and anti-aging research.

    Science.gov (United States)

    Ruan, Qingwei; Ma, Cheng; Zhang, Ruxin; Yu, Zhuowei

    2014-01-01

    The development of presbycusis, or age-related hearing loss, is determined by a combination of genetic and environmental factors. The auditory periphery exhibits a progressive bilateral, symmetrical reduction of auditory sensitivity to sound from high to low frequencies. The central auditory nervous system shows symptoms of decline in age-related cognitive abilities, including difficulties in speech discrimination and reduced central auditory processing, ultimately resulting in auditory perceptual abnormalities. The pathophysiological mechanisms of presbycusis include excitotoxicity, oxidative stress, inflammation, aging and oxidative stress-induced DNA damage that results in apoptosis in the auditory pathway. However, the originating signals that trigger these mechanisms remain unclear. For instance, it is still unknown whether insulin is involved in auditory aging. Auditory aging has preclinical lesions, which manifest as asymptomatic loss of periphery auditory nerves and changes in the plasticity of the central auditory nervous system. Currently, the diagnosis of preclinical, reversible lesions depends on the detection of auditory impairment by functional imaging, and the identification of physiological and molecular biological markers. However, despite recent improvements in the application of these markers, they remain under-utilized in clinical practice. The application of antisenescent approaches to the prevention of auditory aging has produced inconsistent results. Future research will focus on the identification of markers for the diagnosis of preclinical auditory aging and the development of effective interventions.

  16. Current pathways for epidemiological research in amyotrophic lateral sclerosis

    Science.gov (United States)

    FACTOR-LITVAK, PAM; AL-CHALABI, AMMAR; ASCHERIO, ALBERTO; BRADLEY, WALTER; CHÍO, ADRIANO; GARRUTO, RALPH; HARDIMAN, ORLA; KAMEL, FREYA; KASARSKIS, EDWARD; MCKEE, ANN; NAKANO, IMAHARU; NELSON, LORENE M.; EISEN, ANDREW

    2017-01-01

    Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease. The current status of the epidemiology, challenges to its study, and novel study design options are discussed in this paper. We focus on recent results from large-scale population based prospective studies, case-control studies and population based registries, risk factors, and neuropathologic findings in chronic traumatic encephalomyelopathy. We identify areas of interest for future research, including time-trends in the incidence and prevalence of ALS; the meaning of lifetime risk; the phenotypic description of ALS; the definition of familial versus sporadic ALS, syndromic aspects of ALS; specific risk factors such as military service, life style factors such as smoking, the use of statins, and the presence of β-N-methylamino-L-alanine (BMAA), an excitotoxic amino acid derivative possibly produced by cyanobacteria found in almost every terrestrial and aquatic habitat; the emergence and disappearance of an endemic ALS in areas of the Pacific; and gene-environment interactions in the etiology of ALS. To move the epidemiology forward, we suggest using well-characterized cohorts of newly diagnosed ALS patients to identify risk and prognostic factors; storing biological material for future studies; building on the National ALS Registry as a resource of future studies; working in multidisciplinary consortia; and addressing the possible early life etiology of ALS. PMID:23678878

  17. Sleep disturbance due to noise: Current issues and future research

    Directory of Open Access Journals (Sweden)

    Ken Hume

    2010-01-01

    Full Text Available There is growing interest in carrying out further research to understand and reduce the impact of aircraft noise on airport neighborhood in anticipation of the projected substantial increase in global aviation. Soundscapes provide new analytical methods and a broader, more comprehensive appreciation of the aural environment, which may have a useful role in understanding noise-induced sleep disturbance and annoyance. Current noise metrics like Leq do not provide a common language to report noise environment to residents, which is a key obstacle to effective noise management and acceptance. Non-auditory effects complicate the production of consistent dose-response functions for aircraft noise affecting sleep and annoyance. There are various end-points that can be chosen to assess the degree of sleep disturbance, which has detracted from the clarity of results that has been communicated to wider audiences. The World Health Organization (WHO-Europe has produced Night Noise Guidelines for Europe, which act as a clear guide for airports and planners to work towards. Methodological inadequacies and the need for simpler techniques to record sleep will be considered with the exciting potential to greatly increase cost-effective field data acquisition, which is needed for large scale epidemiological studies

  18. Alcohol and NMDA Receptor: Current research and future direction

    Directory of Open Access Journals (Sweden)

    Raman eChandrasekar

    2013-05-01

    Full Text Available The brain is one of the major targets of alcohol actions. Most of the excitatory synaptic transmission in the central nervous system is mediated by NMDA receptors. However, one of the most devastating effects of alcohol leads to brain shrinkage, loss of nerve cells at specific regions through a mechanism involving excitotoxicity, oxidative stress. Earlier studies have indicated that chronic exposure to ethanol both in vivo and in vitro, increases NR1 and NR2B gene expression and their polypeptide levels. The effect of alcohol and molecular changes on the regulatory process, which modulates NMDAR functions including factors altering transcription, translation, post-translational modifications and protein expression, as well as those influencing their interactions with different regulatory proteins (downstream effectors are incessantly increasing at the cellular level. Further, I discuss the various genetically altered mice approaches that have been used to study NMDA receptor subunits and their functional implication. In a recent countable review, epigenetic dimension (i.e., histone modification-induced chromatin remodeling and DNA methylation, in the process of alcohol related neuroadapation is one of the key molecular mechanisms in alcohol mediated NMDAR alteration. Here, I provide a recount on what has already been achieved, current trends and how the future research/studies of the NMDA receptor might lead to even greater engagement with many possible new insights into the neurobiology and treatment of alcoholism.

  19. Alcohol and NMDA receptor: current research and future direction.

    Science.gov (United States)

    Chandrasekar, Raman

    2013-01-01

    The brain is one of the major targets of alcohol actions. Most of the excitatory synaptic transmission in the central nervous system is mediated by N-methyl-D-aspartate (NMDA) receptors. However, one of the most devastating effects of alcohol leads to brain shrinkage, loss of nerve cells at specific regions through a mechanism involving excitotoxicity, oxidative stress. Earlier studies have indicated that chronic exposure to ethanol both in vivo and in vitro, increases NR1 and NR2B gene expression and their polypeptide levels. The effect of alcohol and molecular changes on the regulatory process, which modulates NMDAR functions including factors altering transcription, translation, post-translational modifications, and protein expression, as well as those influencing their interactions with different regulatory proteins (downstream effectors) are incessantly increasing at the cellular level. Further, I discuss the various genetically altered mice approaches that have been used to study NMDA receptor subunits and their functional implication. In a recent countable review, epigenetic dimension (i.e., histone modification-induced chromatin remodeling and DNA methylation, in the process of alcohol related neuroadaptation) is one of the key molecular mechanisms in alcohol mediated NMDAR alteration. Here, I provide a recount on what has already been achieved, current trends and how the future research/studies of the NMDA receptor might lead to even greater engagement with many possible new insights into the neurobiology and treatment of alcoholism.

  20. Rethinking cancer: current challenges and opportunities in cancer research.

    Science.gov (United States)

    Cagan, Ross; Meyer, Pablo

    2017-04-01

    Cancer therapeutics currently have the lowest clinical trial success rate of all major diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon be the leading cause of mortality in developed countries. As a disease embedded in the fundamentals of our biology, cancer presents difficult challenges that would benefit from uniting experts from a broad cross-section of related and unrelated fields. Combining extant approaches with novel ones could help in tackling this challenging health problem, enabling the development of therapeutics to stop disease progression and prolong patient lives. This goal provided the inspiration for a recent workshop titled 'Rethinking Cancer', which brought together a group of cancer scientists who work in the academic and pharmaceutical sectors of Europe, America and Asia. In this Editorial, we discuss the main themes emerging from the workshop, with the aim of providing a snapshot of key challenges faced by the cancer research community today. We also outline potential strategies for addressing some of these challenges, from understanding the basic evolution of cancer and improving its early detection to streamlining the thorny process of moving promising drug targets into clinical trials. © 2017. Published by The Company of Biologists Ltd.

  1. Rethinking cancer: current challenges and opportunities in cancer research

    Directory of Open Access Journals (Sweden)

    Ross Cagan

    2017-04-01

    Full Text Available Cancer therapeutics currently have the lowest clinical trial success rate of all major diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon be the leading cause of mortality in developed countries. As a disease embedded in the fundamentals of our biology, cancer presents difficult challenges that would benefit from uniting experts from a broad cross-section of related and unrelated fields. Combining extant approaches with novel ones could help in tackling this challenging health problem, enabling the development of therapeutics to stop disease progression and prolong patient lives. This goal provided the inspiration for a recent workshop titled ‘Rethinking Cancer’, which brought together a group of cancer scientists who work in the academic and pharmaceutical sectors of Europe, America and Asia. In this Editorial, we discuss the main themes emerging from the workshop, with the aim of providing a snapshot of key challenges faced by the cancer research community today. We also outline potential strategies for addressing some of these challenges, from understanding the basic evolution of cancer and improving its early detection to streamlining the thorny process of moving promising drug targets into clinical trials.

  2. Sediment pollution of the Elbe River side structures - current research

    Science.gov (United States)

    Chalupova, Dagmar; Janský, Bohumír

    2016-04-01

    The contribution brings the summarized results of a long-term research on sediment pollution of side structures of the Elbe River over the last 14 years. The investigation has been focused on old anthropogenic pollution of sediment cores taken from fluvial lakes and floodplain, as the sampling of deeper sediments outside the riverbed is not a part of systematic monitoring of sediment pollution of the Elbe. The Elbe River floodplain has been influenced by human activities since the Middle Ages, but the main anthropogenic pollution have been produced in the 20th century. The studied localities were chosen with the respect to the distance from the source of industrial pollution, the intensity of hydrological communication with the river and the surrounding landuse to determine the extend and the level of anthropogenic contamination in the Elbe River floodplain ecosystem. Apart from bathymetric measurements, observation of the hydrological regime in several fluvial lakes or water quality sampling at some localities, the research was focused above all on determination of metal concentrations (Ag, Cd, Cr, Cu, Fe, Hg, Mn, Pb, Zn) in all taken sediment cores, specific organic compounds (PCBs, DDT, HCH, HCB, PAHs etc.), total organic carbon at some localities and grain structure analyses. The data were also compared with the results of systematic sediment monitoring from the nearest riverbed sampling stations on the Elbe River. The highest concentrations of metals and specific organic compounds were determined in the sediments taken from fluvial lakes and floodplain (Zimní přístav PARAMO, Rosice fuvial Lake, Libiš pool etc.) situated in the vicinity of the main Elbe River polluters - Synthesia chemical plant and PARAMO refinery in Pardubice or Spolana chemical plant near Neratovice. However, there was also determined a significant role of the hydrological communication with the river proved with lower sediment pollution in separated localities. The realization of the

  3. [Pathological gambling and computergame-addiction. Current state of research regarding two subtypes of behavioural addiction].

    Science.gov (United States)

    Wölfling, K; Müller, K W

    2010-04-01

    Behavioral addictions, like pathological gambling and computer game addiction (or internet addiction), have become a growing concern in research and public interest. Currently similarities between behavioral addictions and substance dependency are controversially discussed in the scientific community. Unfortunately a mismatch exists between the large number of people seeking treatment and the small number of scientific studies on pathological gambling and computer game addiction. Prevalence of pathological gambling among the German population is estimated to be 0.2-0.5%. These estimations are comparable to prevalence rates reported for drug dependency. Latest research states that about 3% of German adolescents and young adults are believed to suffer from computer game addiction. Therefore, it is important to enhance investigations regarding the clinical and neuroscientific basis of computer game addiction. This review offers a summary of current results of research regarding pathological gambling and internet addiction. The phenomenological description of these two disorders is meant to allow a deeper understanding of behavioral addictions.

  4. White Paper on Multicarrier Excitation of Multipactor Breakdown: A Survey of Current Methods and Research Opportunities

    Science.gov (United States)

    2015-06-18

    AEROSPACE REPORT NO. TOR-2015-02548 White Paper on Multicarrier Excitation of Multipactor Breakdown: A Survey of Current Methods and...voltage phenomena where the verification power level is chosen such that the maximum instantaneous operational voltage in the component is excited . In...analysis methods under investigation for multicarrier excitation threshold prediction based on a survey of the research literature. In general, this

  5. Summary of current research on Central Asian vortex

    Directory of Open Access Journals (Sweden)

    Lian-Mei YANG

    2017-03-01

    Full Text Available The Central Asian vortex (CAV is an important synoptic-scale system that causes rainstorms, short-term heavy precipitation, hail, and sustained low temperatures in Xinjiang. This paper summarizes the current research conducted on the CAV since the 1960s. The objective definition of the CAV has been revised and a deep and shallow CAV classification proposed. Two high-frequency areas of deep CAV activity are the Kazakhstan hills (Sayan mountains and the eastern area of the Aral Sea (Tashkent; events mostly occur in summer and 40% cause strong rainfall. In addition, two high-frequency activity areas of the shallow CAV are located in the west and south of the Pamirs Plateau and mostly occur in spring; 23.2% of occurrences cause strong rainfall. The western and eastern water vapor transport relates to westerlies and a strong low-level easterly jet stream (LLEJ extending from Gansu to Xinjiang, respectively, and water vapor over the Tibetan Plateau transports even more northwards and enters Xinjiang. The deep CAV has an obvious cold core structure down to 300 hPa. The conversion terms from eddy available potential energy (AE to eddy kinetic energy (KE and eddy kinetic energy inflow (BKE from the open atmospheric region boundaries are the main sources of KE which cause rapid development of the CAV. The anomalous anti-cyclone center over the northeast Atlantic is the fountain of Rossby wave energy dispersion; Rossby waves propagate from the northeast Atlantic to eastern Europe (Urals (EEU, and then continuously propagate to Central Asia causing development of the CAV. The CAV requires further study to characterize the meso-scale system structure and evolution characteristics. In addition, physical modeling of the severe convective weather occurring under the CAV is required to determine the critical impacts of this severe convective weather and enable forecasting and early-warning indexes.

  6. A sequential mixed methods research approach to investigating HIV ...

    African Journals Online (AJOL)

    A sequential mixed methods research approach to investigating HIV/AIDS intervention ... the HIV/AIDS pandemic has seen construction management taking on a vital ... commenced with a quantitative survey to establish base-line information.

  7. [Current situation of toxicity classification of Chinese materia medica and its research thoughts].

    Science.gov (United States)

    Sun, Wenyan; Hou, Xiujuan; Wang, Bin; Zhu, Yuelan; Zhang, Shuofeng; Chang, Hongsheng; Sun, Jianning

    2012-08-01

    Toxicity of Chinese materia medica (CMM) is an important part of Chinese herbal nature theory. In clinical application, the dosage, time limitation and compatibility of CMM is mainly determined by toxicity. At present, there is no uniform toxicity classification standard for the evaluation of Chinese herbal toxicity. Therefore, it is significant to research toxicity classification of CMM. The current situation of toxicity classification of CMM is reviewed in this paper, and proposed research thoughts are as follows: the measurement of toxicity parameters, the confirmation of poisoning target organs, the investigation on toxic mechanism by serum pharmacology and toxicokinetics, the comprehensive evaluation on toxicity based on quantitative theory.

  8. International Inventory of Current Mexico-Related Research. Volume 4.

    Science.gov (United States)

    Montoya, Ricardo Anzaldua, Ed.; And Others

    The fourth annual research inventory describes 728 Mexican-related research projects being conducted in 1984 or to begin in 1985 in 14 countries. Data come from questionnaires sent during 1984 to more than 1,800 individual researchers and 650 institutions around the world. Each project description provides names and addresses of principal and…

  9. Current developments in environmental psychology : topics and researchers

    NARCIS (Netherlands)

    van der Werff, Ellen; Perlaviciute, Goda; Muinos, Gabriel

    2016-01-01

    The aim of this special issue is to bring the work of early-career researchers in environmental psychology to the spotlight. These young researchers come from different countries and cultures, have their own theoretical approaches and employ different research methods to increase knowledge on the re

  10. Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities

    Science.gov (United States)

    Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities, a 2013 workshop sponsored by the Epidemiology and Genomics Research Program.

  11. Neonatal research in India: current status, challenges, and the way forward.

    Science.gov (United States)

    Gupta, Shuchita; Chaurasia, Suman; Sankar, M Jeeva; Deorari, Ashok K; Paul, Vinod K; Agarwal, Ramesh

    2014-11-01

    The present article systematically reviews the current status of neonatal research in India by examining the research articles published by Indian authors in the last 10 years. It also enlists the major challenges and proposes a few potential solutions to improve the status of neonatal research in the country. The systematic review of 574 eligible articles indicates that majority of the studies were observational in nature, facility-based, and primarily investigator-driven with no external funding, had small sample size, and were published in journals with low impact factor. Only a few select government and non-government academic institutions contributed to most studies. The major challenges include shortage of faculty, no provision for dedicated research time, inadequate knowledge/skills in research methods, lack of funding opportunities, limited access to literature, non-existence of research administrative cell, inappropriately low perks to research staff, and poor support for data management and statistical analysis. The recently revised guidelines on clinical trials involving drugs have further increased the researcher's dilemma. The potential solutions are to increase the faculty strength in medical colleges, allow dedicated research time to them, appoint dedicated research cadre with emoluments at par with clinical faculty, initiate formal training in research methods, create nationwide free portal for access to literature, facilitate development of good protocols through technical guidance at all stages, make the process of funding quick and transparent, and to promote collaborative trans-disciplinary research. Experts from different domains should come together and formulate evidence based research priorities. Regulatory mechanisms should be kept proportionate to plausible risks of research, and detailed ethical guidelines for research in children should be formulated. And last but not least, harnessing postgraduate thesis potential to answer simple and

  12. Investigation of current status in Europe and USA on boron neutron capture therapy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-11-01

    This report describes on the spot investigation results of current status of medical irradiation in Europe and USA at Feb. 1999. In HFR (Netherlands), the phase 1 study with the Joint Research Centre (JRC) of the EU had been already finished in those days, at the same time, an improvement of medical irradiation field of VTT(Finland) had been finishing and then clinical trial research had been about to start. On the other hand, phase 1 studies by two groups of BNL (Brook heaven National Laboratory) and MIT (Nuclear Engineering of Massachusetts Institute of Technology) in US were now in almost final stage, and they would start on phase 2 study. Either reactors of MIT and BNL were in modification to increase neutron flux, especially that employing fission converter into the irradiation facility and installation of irradiation room were carrying out in the former. In Europe and USA, the accelerator-based BNCT planes are now in progress vigorously, and will have reality. A reform of dynamitron accelerator at University of Birmingham was progressed, and the clinical treatment would be started from September 2000. The accelerator group at MIT has a small type of tandem accelerator, and they were performing basic experiment for BNCS (Boron Neutron Capture Synovectomy) with this accelerator. The concept design for an accelerator and a moderator had been finished at Lawrence Berkeley National Laboratory and University of Berkeley. (author)

  13. Bibliometric Analysis of Current Web Survey Research in China

    Institute of Scientific and Technical Information of China (English)

    ZHANG Qian; SHAO Peiji; FANG Jiaming

    2008-01-01

    In recent years, with the advancement of information technology and its application in survey activities, web surveys have not only greatly developed, but have also encountered many problems in China. An analysis of domestic research is important for better understanding of web surveys, to guide further research and application. This paper gives a bibliometric analysis of 120 domestic articles on web surveys from 1998 to 2006, on publication growth, author and organization distribution, journal distribution, and research subjects. Research on web surveys in China should make progress comparable with research abroad in comparative studies, specific studies, and technical application studies.

  14. Research and design of a novel current mode charge pump

    Science.gov (United States)

    Xianrui, Li; Xinquan, Lai; Yushan, Li; Qiang, Ye

    2009-10-01

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transconductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice simulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 μs, and the load current jumps from 400 to 800 mA.

  15. Research and design of a novel current mode charge pump

    Energy Technology Data Exchange (ETDEWEB)

    Li Xianrui; Lai Xinquan; Li Yushan; Ye Qiang, E-mail: lixianrui4213@126.co [Research Institute of Design Circuit, Xidian University, Xi' an 710071 (China)

    2009-10-15

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transconductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice simulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 {mu}s, and the load current jumps from 400 to 800 mA.

  16. Research and design of a novel current mode charge pump

    Institute of Scientific and Technical Information of China (English)

    Li Xianrui; Lai Xinquan; Li Yushan; Ye Qiang

    2009-01-01

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transcon ductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice sim ulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 μs, and the load current jumps from 400 to 800 mA.

  17. Current status of research on biophysical effects of ultrasound.

    Science.gov (United States)

    Barnett, S B; ter Haar, G R; Ziskin, M C; Nyborg, W L; Maeda, K; Bang, J

    1994-01-01

    This overview of bioeffects of ultrasound presents some key aspects of selected papers dealing with biophysical end-points. Its purpose is to establish a basis for exposure and dosimetric standards for medical ultrasonic equipment. It is intended to provide essential background resource material for the medical/scientific community, and more specifically for scientific working groups. This document was prepared by members of the Safety Committee of the World Federation for Ultrasound in Medicine and Biology. It was produced as a resource document in response to a request for information by Working Group 12 (Ultrasound exposure parameters) of the International Electrotechnical Commission Technical Committee 87, Ultrasonics. IEC TC 87, WG12 is the working group responsible for generating international standards for the classification of equipment by its acoustic fields based on safety thresholds. Our paper is intended to update and supplement information on the thermal mechanism provided in the publication, "WFUMB Symposium on Safety and Standardisation in Medical Ultrasound: Issues and Recommendations Regarding Thermal Mechanisms for Biological Effects of Ultrasound" (WFUMB 1992). It also provides an overview of trends in research into nonthermal mechanisms as a preliminary to the next WFUMB Symposium on Safety of Medical Ultrasound when this subject will be examined in detail by a select group of international experts. The WFUMB-sponsored workshop will take place in Utsunomiya, Japan during 11-15th July, 1994. The purpose of the meeting is to evaluate the scientific literature and to formulate internationally accepted recommendations on the safe use of diagnostic ultrasound that may be endorsed as official policy of the WFUMB. It should be noted that the current publication is not intended for review or endorsement as an official WFUMB document. It is produced as a scientific paper by individuals who are members of the WFUMB Safety Committee, and it therefore

  18. 系外行星大气研究现状%Current Investigations on Exoplanetary Atmospheres

    Institute of Scientific and Technical Information of China (English)

    田蕾; 季江徽

    2015-01-01

    The ultimate goal for detecting exoplanets is to search for extraterrestrial life and habitable terrestrial planets. The exoplanetary atmosphere acts as a good window to understand exoplanet’s characteristics and habitability. Hence, such investigation is one of the most significant frontiers in astronomy. In the last decade, tremendous achievements have been made on the theories of the exoplanetary atmosphere, and observations through photometric and spectroscopic methods using a variety of space-borne and ground-based observational facilities. However, currently the atmosphere observations mainly come from transiting hot Jupiters, super-Earths and direct imaging giant planets, because of limitation in current observational techniques. The present review attempts to succinctly summarize current investigations in this field. First, we briefly describe the methods of observing exoplanetary atmospheres. Next, we review the fundamental facts, nowadays research progress of atmospheres for hot Jupiters and super-Earths. Finally,we present an introduction of the projects, which are involved in exoplanetary atmosphere detection to show the bright prospects for future investigation.%探测系外行星的最终目的是为了寻找系外生命和宜居行星,而系外行星大气是人们了解行星宜居特性的窗口,所以系外行星大气的研究至关重要。近10年来,系外行星大气的理论研究和观测都发展迅速。受观测技术限制,目前观测到大气的系外行星主要是用凌星法探测到的热木星和超级地球,还有用直接成像法探测到的离主星较远的年轻气态巨行星。力求在系外行星大气领域飞速发展之际,对该领域研究现状做简明介绍。首先介绍系外行星大气的观测方法,随后介绍热木星和超级地球的大气概况和研究现状,最后对系外行星大气探测的有关项目进行简要介绍,以展示未来系外行星大气研究的前景。

  19. Dual use research: investigation across multiple science disciplines.

    Science.gov (United States)

    Oltmann, Shannon

    2015-04-01

    Most recent studies of dual use research have focused on the life sciences, although some researchers have suggested that dual use research occurs across many disciplines. This research is an initial investigation into the prevalence of dual use research in other scientific disciplines by surveying senior editors of scientific journals, drawn from Journal Citation Reports. The survey was emailed to 7,500 journal editors with a response rate of 10.1 %. Approximately 4.8 % of life science editors reported they had to consider whether to publish dual use research and 38.9 % said they decided to not publish the research in question. In disciplines other than the life sciences, 7.2 % of editors from other science disciplines reported that they had to consider whether to publish dual use research, and 48.4 % declined to publish it. The survey investigated relationships between dual use and the journal's source of funding and place of publication, but no relationships were found. Further research is needed to better understand the occurrence of dual use research in other science disciplines.

  20. Investigation and Analysis of Current Writing Teaching Mode among English Majors in Normal Universities in China

    Science.gov (United States)

    Zeng, Hang-li

    2010-01-01

    This paper has made an investigation on the current writing teaching mode among English majors in normal universities in China, by means of questionnaire, interview and class observation. The study finds out that the current writing teaching mode is not purely product approach or process approach. In fact, the two approaches to writing co-exist in…

  1. Statistical research on the motion properties of the magnetotail current sheet:Cluster observations

    Institute of Scientific and Technical Information of China (English)

    H.REME; E.LUCEK

    2010-01-01

    The origin of the flapping motion of the earth’s magnetotail current sheet is one of the most important problems in the magnetotail dynamics.Using Cluster data,we make a statistical research on the motion properties of the magnetotail current sheet of 2001 and 2003.We calculate the velocities of the magnetotail current sheet using new methods and obtain the distribution of the magnetotail current sheet velocities in the X-Y plane in GSE coordinate system.Our results show that although most of the current sheets were propagating toward the tail flanks and those of the exceptions lay in dusk side,which is consistent with previous studies,the proportions of the current sheet which were propagating toward midnight (where |YGSE|=0) were higher than those in previous studies.Motions of the current sheet in the middle area (|YGSE|<8 Re) of the magnetotail are investigated.Relatively high value of the Z component of the velocity further confirms that the middle area of the magnetotail might be a source region for the motion of the current sheets which were propagating towards the tail flanks.According to our case studies,the way the current sheets propagated toward midnight area differs significantly from that toward dusk and dawn side,from which we infer that there might be two different kinds of current sheet motions originated from different sources.The statistical results of this paper may give some clues for further studies on the origin of the flapping motion of the magnetotail current sheet.

  2. The current status of nuclear research reactor in Thailand

    Energy Technology Data Exchange (ETDEWEB)

    Sittichai, C.; Kanyukt, R.; Pongpat, P. [Office of Atomic Energy for Peace, Bangkok (Thailand)

    1998-10-01

    Since 1962, the Thai Research Reactor has been serving for various kinds of activities i.e. the production of radioisotopes for medical uses and research and development on nuclear science and technology, for more than three decades. The existing reactor site should be abandoned and relocated to the new suitable site, according to Thai cabinet`s resolution on the 27 December 1989. The decommissioning project for the present reactor as well as the establishment of new nuclear research center were planned. This paper discussed the OAEP concept for the decommissioning programme and the general description of the new research reactor and some related information were also reported. (author)

  3. Urban tourism research : Recent progress and current paradoxes

    NARCIS (Netherlands)

    Ashworth, Gregory; Page, Stephen J.

    Urban tourism has remained a consistent theme in the expansion of tourism research since the 1980s and several seminal papers (e.g. Ashworth, 1989, 2003) have reviewed the state of research and its progress towards a greater recognition. This Progress in Tourism Management review article moves our

  4. The Research on School Marketing: Current Issues and Future Directions

    Science.gov (United States)

    Oplatka, Izhar; Hemsley-Brown, Jane

    2004-01-01

    This review provides a synthesis of the scholarship that has sought to expand the understanding of educational marketing practice in schools. The following research questions guided this review. What are the common themes and characteristics that emerge from research about marketing in schools? What remains underdeveloped in the characterization…

  5. Postgraduate Research Supervision: A Critical Review of Current Practice

    Science.gov (United States)

    McCallin, Antoinette; Nayar, Shoba

    2012-01-01

    Changes in the funding and delivery of research programmes at the university level have, in recent years, resulted in significant changes to research supervision. This paper critically reviews key influences effecting postgraduate supervision. Analysis draws on literature spanning 2000-2010 to determine the appropriateness of traditional models of…

  6. Urban tourism research : Recent progress and current paradoxes

    NARCIS (Netherlands)

    Ashworth, Gregory; Page, Stephen J.

    2011-01-01

    Urban tourism has remained a consistent theme in the expansion of tourism research since the 1980s and several seminal papers (e.g. Ashworth, 1989, 2003) have reviewed the state of research and its progress towards a greater recognition. This Progress in Tourism Management review article moves our u

  7. Human memory research: Current hypotheses and new perspectives

    Directory of Open Access Journals (Sweden)

    Antônio Jaeger

    Full Text Available Abstract Research on human memory has increased significantly in the last few decades. Inconsistencies and controversies inherent to such research, however, are rarely articulated on published reports. The goal of the present article is to present and discuss a series of open questions related to major topics on human memory research that can be addressed by future research. The topics covered here are visual working memory, recognition memory, emotion and memory interaction, and methodological issues of false memories studies. Overall, the present work reveals a series of open questions and alternative analysis which could be useful for the process of hypothesis generation, and consequently for the design and implementation of future research on human memory.

  8. Incorporating current research into formal higher education settings using Astrobites

    Science.gov (United States)

    Sanders, Nathan E.; Kohler, Susanna; Faesi, Chris; Villar, Ashley; Zevin, Michael

    2017-10-01

    A primary goal of many undergraduate- and graduate-level courses in the physical sciences is to prepare students to engage in scientific research or to prepare students for careers that leverage skillsets similar to those used by research scientists. Even for students who may not intend to pursue a career with these characteristics, exposure to the context of applications in modern research can be a valuable tool for teaching and learning. However, a persistent barrier to student participation in research is familiarity with the technical language, format, and context that academic researchers use to communicate research methods and findings with each other: the literature of the field. Astrobites, an online web resource authored by graduate students, has published brief and accessible summaries of more than 1300 articles from the astrophysical literature since its founding in 2010. This article presents three methods for introducing students at all levels within the formal higher education setting to approaches and results from modern research. For each method, we provide a sample lesson plan that integrates content and principles from Astrobites, including step-by-step instructions for instructors, suggestions for adapting the lesson to different class levels across the undergraduate and graduate spectrum, sample student handouts, and a grading rubric.

  9. Review of current research on hydrocarbon production by plants

    Energy Technology Data Exchange (ETDEWEB)

    Benedict, H. M.; Inman, B.

    1979-01-01

    This review assesses the status of research and development in the area of plants that produce hydrocarbons as a possible replacement for traditional fossil fuels. The information is meant to be used as a basis for determining the scope of a possible R and D program by DOE/FFB. Except in the case of guayule (Parthenium argentatum Gray), research on hydrocarbon species generally has not advanced beyond preliminary screening, extraction, and growth studies. Virtually no field studies have been initiated; hydrocarbon component extraction, separation, identification, and characterization have been only timidly approached; the biochemistry of hydrocarbon formation remains virtually untouched; and potential market analysis has been based on insufficient data. Research interest is increasing in this area, however. Industrial interest understandably centers about guayule prospects and is supplemented by NSF and DOE research funds. Additional support for other research topics has been supplied by DOE and USDA and by certain university systems. Due to the infant state of technology in this area of energy research, it is not possible to predict or satisfactorily assess at this time the potential contribution that plant hydrocarbons might make toward decreasing the nation's dependence upon petroleum. However, the general impression received from experts interviewed during this review was that the major thrust of research should be directed toward the manufacture of petrochemical substitutes rather than fuel production.

  10. Review of current research on hydrocarbon production by plants

    Energy Technology Data Exchange (ETDEWEB)

    Benedict, H. M.; Inman, B.

    1979-01-01

    This review assesses the status of research and development in the area of plants that produce hydrocarbons as a possible replacement for traditional fossil fuels. The information is meant to be used as a basis for determining the scope of a possible R and D program by DOE/FFB. Except in the case of guayule (Parthenium argentatum Gray), research on hydrocarbon species generally has not advanced beyond preliminary screening, extraction, and growth studies. Virtually no field studies have been initiated; hydrocarbon component extraction, separation, identification, and characterization have been only timidly approached; the biochemistry of hydrocarbon formation remains virtually untouched; and potential market analysis has been based on insufficient data. Research interest is increasing in this area, however. Industrial interest understandably centers about guayule prospects and is supplemented by NSF and DOE research funds. Additional support for other research topics has been supplied by DOE and USDA and by certain university systems. Due to the infant state of technology in this area of energy research, it is not possible to predict or satisfactorily assess at this time the potential contribution that plant hydrocarbons might make toward decreasing the nation's dependence upon petroleum. However, the general impression received from experts interviewed during this review was that the major thrust of research should be directed toward the manufacture of petrochemical substitutes rather than fuel production.

  11. [Current situation and development trend of Chinese medicine information research].

    Science.gov (United States)

    Dong, Yan; Cui, Meng

    2013-04-01

    Literature resource service was the main service that Chinese medicine (CM) information offered. But in recent years users have started to request the health information knowledge service. The CM information researches and application service mainly included: (1) the need of strength studies on theory, application of technology, information retrieval, and information standard development; (2) Information studies need to support clinical decision making, new drug research; (3) Quick response based on the network monitoring and support to emergency countermeasures. CM information researches have the following treads: (1) developing the theory system structure of CM information; (2) studying the methodology system of CM information; (3) knowledge discovery and knowledge innovation.

  12. Current research trends in mountain biodiversity in NW Europe

    Directory of Open Access Journals (Sweden)

    Väisänen, Risto A.

    1998-12-01

    Full Text Available Focusing on four themes in relation to biodiversity (vegetation science, keystone grazers, long-term studies and protected areas, a synthesis of current research in the mountain areas of Fennoscandia, Iceland and Scotland is presented. Recent relevant advances in vegetation science include classifications of mountain habitats which together with species distribution maps offer new possibilities for analysis. Generalisations emerging from comparisons of the ecology and ecophysiology of plants between different mountain areas are greatly needed. Further studies on the ecological impacts of keystone grazers are urgently required because of the alarming rate of degradation of mountain habitats. The topics highlighted from northern Fennoscandia include (i the effect of overgrazing by reindeer on the cover of foliose lichens and on the regeneration of mountain birch, (ii the ecological interactions between the autumnal moth and mountain birch, and (Hi the effect of rodents on vegetation. Long-term studies of slow processes to capture rare but important events are needed to better understand the functioning of mountain ecosystems. Examples of such studies are presented for (i the moss Racomitrium lanuginosum as an indicator of airborne nitrogen pollution, (ii research based on cyclic oscillations of vole numbers, and (Hi the application of breeding birds in environmental assessment. The conservation of appropriate areas is important for mountain biodiversity. Mountain habitats have been protected extensively in northern Europe. The evaluation of how representative the existing areas are and how to use them for research need international co-ordination.

    [fr] On présente une synthèse de la recherche actuelle dans les régions de montagne de la Scandinavie, l'Islande et l'Ecosse, centrée sur quatre sujets autour de la biodiversité (science de la végétation, herbivores principaux, études à long terme et zones protégées. Les r

  13. Relationship Education Research: Current Status and Future Directions

    Science.gov (United States)

    Markman, Howard J.; Rhoades, Galena K.

    2011-01-01

    The overarching aim of this paper is to review research on relationship education programs and approaches that have been published or accepted for publication since the last review article in 2002. This paper provides a critical overview of the relationship education field and sets an agenda for research and practice for the next decade. A theme weaved throughout the paper are the ways in which relationship education is similar and different from couples therapy and we conclude that there can be a synergistic, healthy marriage between the two. We then provide recommendations for future directions for research in the relationship education field. Finally, the co-authors comment on our experiences in both the relationship education field and couples therapy field as both researchers and interventionists. PMID:22283386

  14. Research on cancer diagnosis in Malaysia: current status.

    Science.gov (United States)

    Looi, L M; Zubaidah, Z; Cheah, P L; Cheong, S K; Gudum, H R; Iekhsan, O; Ikram, S I; Jamal, R; Mak, J W; Othman, N H; Puteri, J N; Rosline, H; Sabariah, A R; Seow, H F; Sharifah, N A

    2004-06-01

    Cancer is a major morbidity and mortality concern in Malaysia. Based on National Cancer Registry data, the Malaysian population is estimated to bear a cancer burden of about 40,000 new cases per year, and a cumulative lifetime risk of about 1:4. Cancer research in Malaysia has to consider needs relevant to our population, and resources constraints. Hence, funding bodies prioritise cancers of high prevalence, unique to our community and posing specific clinical problems. Cancer diagnosis is crucial to cancer management. While cancer diagnosis research largely aims at improvements in diagnostic information towards more appropriate therapy, it also impacts upon policy development and other areas of cancer management. The scope of cancer diagnosis upon which this paper is based, and their possible impact on other R&D areas, has been broadly categorized into: (1) identification of aetiological agents and their linkages to the development of precancer and cancer (impact on policy development, cancer prevention and treatment), (2) cancer biology and pathogenesis (impact on cancer prevention, treatment strategies and product development), (3) improvements in accuracy, sensitivity and specificity in cancer detection, monitoring and classification (impact on technology development) and (4) prognostic and predictive parameters (impact on treatment strategies). This paper is based on data collected by the Working Group on Cancer Diagnosis Research for the First National Conference on Cancer Research Coordination in April 2004. Data was collated from the databases of Institutions/Universities where the authors are employed, the Ministry of Science, Technology and Innovation (MOSTI) and targeted survey feedback from key cancer researchers. Under the 7th Malaysia Plan, 76 cancer projects were funded through the Intensified Research in Priority Areas (IRPA) scheme of MOSTI, amounting to almost RM15 million of grant money. 47(61.8%) of these projects were substantially in cancer

  15. MicroRNA Detection: Current Technology and Research Strategies

    Science.gov (United States)

    Hunt, Eric A.; Broyles, David; Head, Trajen; Deo, Sapna K.

    2015-07-01

    The relatively new field of microRNA (miR) has experienced rapid growth in methodology associated with its detection and bioanalysis as well as with its role in -omics research, clinical diagnostics, and new therapeutic strategies. The breadth of this area of research and the seemingly exponential increase in number of publications on the subject can present scientists new to the field with a daunting amount of information to evaluate. This review aims to provide a collective overview of miR detection methods by relating conventional, established techniques [such as quantitative reverse transcription polymerase chain reaction (RT-qPCR), microarray, and Northern blotting (NB)] and relatively recent advancements [such as next-generation sequencing (NGS), highly sensitive biosensors, and computational prediction of microRNA/targets] to common miR research strategies. This should guide interested readers toward a more focused study of miR research and the surrounding technology.

  16. Neuroeconomics: cross-currents in research on decision-making

    NARCIS (Netherlands)

    Sanfey, A.G.; Loewenstein, G.; McClure, S.M.; Cohen, J.D.

    2006-01-01

    Despite substantial advances, the question of how we make decisions and judgments continues to pose important challenges for scientific research. Historically, different disciplines have approached this problem using different techniques and assumptions, with few unifying efforts made. However, the

  17. Symposium: Organizational Health Intervention Research: Current Empirical Developments

    DEFF Research Database (Denmark)

    Ipsen, Christine; Jenny, Gregor

    2014-01-01

    This symposium is one of three symposia submitted by the "International organizational health intervention research partnership". The aim of this symposium is to present new empirical developments based on participatory intervention models. All five studies have developed and applied intervention...

  18. Current research situation of titanium alloys in China

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Titanium and its alloys possess excellent comprehensive properties, and they are widely used in many fields. China pays great attentions to the research on new titanium alloys. This paper mainly reviews the research on new Ti alloys in China, for example, high strength and high toughness Ti alloys, burn resistant Tialloys, high temperature Ti alloys, low cost Ti alloys and so on.New basic theories on Ti alloys developed in China in recent years are also reviewed.

  19. Current research in transcultural psychiatry in the Nordic countries

    DEFF Research Database (Denmark)

    Ekblad, Solvig; Kastrup, Marianne Carisius

    2013-01-01

    This article discusses major themes in recent transcultural psychiatric research in the Nordic countries from 2008 to 2011: (a) epidemiological studies of migration, (b) indigenous populations, and (c) quality of psychiatric care for migrants. Over the past several decades, the populations......, and after migration, with potential effects on their physical, mental, social, and spiritual health. Growing interest in transcultural issues is reflected in the level of scientific research and clinical activity in the field by Nordic physicians, psychologists, social scientists, demographers, medical...

  20. Current status of quantitative rotational spectroscopy for atmospheric research

    Science.gov (United States)

    Drouin, Brian J.; Wlodarczak, Georges; Colmont, Jean-Marcel; Rohart, Francois

    2004-01-01

    Remote sensing of rotational transitions in the Earth's atmosphere has become an important method for the retrieval of geophysical temperatures, pressures and chemical composition profiles that requires accurate spectral information. This paper highlights the current status of rotational data that are useful for atmospheric measurements, with a discussion of the types the rotational lineshape measurements that are not generally available in either online repository.

  1. 2002–2012: 10 Years of Research Progress in Horizontal-Axis Marine Current Turbines

    Directory of Open Access Journals (Sweden)

    Kai-Wern Ng

    2013-03-01

    Full Text Available Research in marine current energy, including tidal and ocean currents, has undergone significant growth in the past decade. The horizontal-axis marine current turbine is one of the machines used to harness marine current energy, which appears to be the most technologically and economically viable one at this stage. A number of large-scale marine current turbines rated at more than 1 MW have been deployed around the World. Parallel to the development of industry, academic research on horizontal-axis marine current turbines has also shown positive growth. This paper reviews previous research on horizontal-axis marine current turbines and provides a concise overview for future researchers who might be interested in horizontal-axis marine current turbines. The review covers several main aspects, such as: energy assessment, turbine design, wakes, generators, novel modifications and environmental impact. Future trends for research on horizontal-axis marine current turbines are also discussed.

  2. Research Diagnostic criteria for Temporomandibular Disorders: current status & future relevance.

    Science.gov (United States)

    Dworkin, S F

    2010-10-01

    The Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), published in 1992, was based on international expert recommendations and available empirical data. The major rationale was to offer a putative diagnostic and classification system whose reliability, validity and clinical usefulness for TMD diagnosis and classification could be scientifically evaluated and then revised using an evidence-based model for successive iterations. The present journal issue attests to the accomplishment of that major objective: the RDC/TMD has been translated into 18 languages and used very extensively in international research. One important component of that research has been to yield reliable and valid data resulting in an evidence-based revision of the RDC/TMD now available for continuing research and clinical application. The present article offers recommendations and speculations regarding how the RDC/TMD may continue to serve the function of guiding future research and, most importantly, serve as an evidence-based diagnostic and classification system to aid in the rational choice of clinical care for TMD sufferers around the world.

  3. An Evolution in Research Practice for Investigating International Business Relationships

    Directory of Open Access Journals (Sweden)

    Anne HAMPTON

    2013-09-01

    Full Text Available The purpose of this paper is to discuss the development and rationale of research methodology for a specific topic of research. The topic in question is an investigation into international business relationships, a complex subject and one that is very topical in the growing world of international business. It is intended to examine the logical development of research practice in our study and to show the changing thought processes and justifications we have made over a period of time. It is hoped that this discussion paper will be helpful to academics and students alike, as so often research methodology is only discussed in terms of the final method/techniques chosen with an emphasis on the technical aspects of the methods rather than relating them to the subject to be researched.

  4. Investigating the feasibility of using transcranial direct current stimulation to enhance fluency in people who stutter.

    Science.gov (United States)

    Chesters, Jennifer; Watkins, Kate E; Möttönen, Riikka

    2017-01-01

    Developmental stuttering is a disorder of speech fluency affecting 1% of the adult population. Long-term reductions in stuttering are difficult for adults to achieve with behavioural therapies. We investigated whether a single session of transcranial direct current stimulation (TDCS) could improve fluency in people who stutter (PWS). In separate sessions, either anodal TDCS (1mA for 20min) or sham stimulation was applied over the left inferior frontal cortex while PWS read sentences aloud. Fluency was induced during the stimulation period by using choral speech, that is, participants read in unison with another speaker. Stuttering frequency during sentence reading, paragraph reading and conversation was measured at baseline and at two outcome time points: immediately after the stimulation period and 1h later. Stuttering was reduced significantly at both outcome time points for the sentence-reading task, presumably due to practice, but not during the paragraph reading or conversation tasks. None of the outcome measures were significantly modulated by anodal TDCS. Although the results of this single-session study showed no significant TDCS-induced improvements in fluency, there were some indications that further research is warranted. We discuss factors that we believe may have obscured the expected positive effects of TDCS on fluency, such as heterogeneity in stuttering severity for the sample and variations across sessions. Consideration of such factors may inform future studies aimed at determining the potential of TDCS in the treatment of developmental stuttering. Copyright © 2016. Published by Elsevier Inc.

  5. Material research for environmental sustainability in Thailand: current trends

    Science.gov (United States)

    Niranatlumpong, Panadda; Ramangul, Nudjarin; Dulyaprapan, Pongsak; Nivitchanyong, Siriluck; Udomkitdecha, Werasak

    2015-06-01

    This article covers recent developments of material research in Thailand with a focus on environmental sustainability. Data on Thailand’s consumption and economic growth are briefly discussed to present a relevant snapshot of its economy. A selection of research work is classified into three topics, namely, (a) resource utilization, (b) material engineering and manufacturing, and (c) life cycle efficiency. Material technologies have been developed and implemented to reduce the consumption of materials, energy, and other valuable resources, thus reducing the burden we place on our ecological system. At the same time, product life cycle study allows us to understand the extent of the environmental impact we impart to our planet.

  6. Current research on parenting styles, dimensions, and beliefs.

    Science.gov (United States)

    Smetana, Judith G

    2017-06-01

    For decades, parenting has been characterized in terms of broad global styles, with authoritative parenting seen as most beneficial for children's development. Concerns with greater sensitivity to cultural and contextual variations have led to greater specificity in defining parenting in terms of different parenting dimensions and greater consideration of the role of parenting beliefs in moderating links between parenting and adjustment. New research includes 'domain-specific' models that describe parents as flexibly deploying different practices depending on their goals, children's needs, and the types of behaviors towards which parenting is directed. These trends are described, and directions for future research are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Material research for environmental sustainability in Thailand: current trends.

    Science.gov (United States)

    Niranatlumpong, Panadda; Ramangul, Nudjarin; Dulyaprapan, Pongsak; Nivitchanyong, Siriluck; Udomkitdecha, Werasak

    2015-06-01

    This article covers recent developments of material research in Thailand with a focus on environmental sustainability. Data on Thailand's consumption and economic growth are briefly discussed to present a relevant snapshot of its economy. A selection of research work is classified into three topics, namely, (a) resource utilization, (b) material engineering and manufacturing, and (c) life cycle efficiency. Material technologies have been developed and implemented to reduce the consumption of materials, energy, and other valuable resources, thus reducing the burden we place on our ecological system. At the same time, product life cycle study allows us to understand the extent of the environmental impact we impart to our planet.

  8. Current research activity in the measurement of thorium and the identification of future research needs.

    Science.gov (United States)

    White, M A; Howe, A M; Rosen, P; Holmes, L

    2001-01-01

    A pre-requisite in the setting and enforcement of regulatory limits for exposure to thorium in the workplace is that thorium and its progeny can be accurately measured. Literature surveys have shown that the majority of thorium measurements were performed using either a radiochemical technique, such as alpha or gamma spectroscopy, or ICP-MS. For many methods. there was a separation step to isolate and pre-concentrate thorium from the sample matrix. Thorium was most commonly measured in geological matrices and industrial materials. A survey of current research activity was performed through distribution of a questionnaire to laboratories and national centres. From the rcsponses, four areas of current activity were identified: (i) development of methods for low level thorium determination, (ii) biological monitoring and metabolism of thorium, (iii) environmental monitoring for thorium, and (iv) health risks from X ray contract media. Two key areas for priority research were identified by the thorium Thematic Network: namely sample preparation methods and for traceable standards and reference materials for thorium analysis.

  9. Research on Predicting Drive Current of Shipborne Satcom Antenna

    Directory of Open Access Journals (Sweden)

    Kong Jinping

    2015-01-01

    Full Text Available Predicting the effect of antenna wind load on servo system precisely is meaningful to ensure the safety of satcom antenna on operation, which can avoid overload operation. In this paper, the computational fluid dynamics is used to proceed numerical computation on the pressure distribution of the reflector and torque of drive shaft under different wind speed, windward angle and angle of pitch of the antenna. The simulation model is built under MATLAB/Simulink simulation environment, and the drive current of the antenna servo system is analyzed under wind load effect and ship swing. Then, a method of predicting drive current of antenna servo system according to the wind speed, wind direction and attitude of the antenna is concluded. And this method is verified by simulation at last.

  10. Research on current e-commerce of tourism in China

    OpenAIRE

    Lei, Jun

    2016-01-01

    The rapid development of e-commerce in China has been accompanied by a similar development in tourism-based e-commerce. Taking the network as the medium, e-commerce has already become the new model for tourism transactions in the information age: By building one convenient bridge between tourism-based enterprises and tourists, can directly influence the profitability of enterprises. The paper will introduce the current development of tourism-based e-commerce websites, by firstly examining...

  11. Current trends in safety testing and toxicological research

    Science.gov (United States)

    Zbinden, G.

    1982-06-01

    The paper reviews current concepts of toxicological evaluation of new drugs and other chemicals. Instead of completing a predetermined check-list toxicologists now consider the potential adverse effects of the substances under actual conditions of use. They then design experimental models which have a high probability to predict the toxic effects. Moreover, the enhanced susceptibilities of special risk populations is more and more taken into consideration.

  12. Transcranial Direct Current Stimulation: Considerations for Research in Adolescent Depression

    Directory of Open Access Journals (Sweden)

    Jonathan C. Lee

    2017-06-01

    Full Text Available Adolescent depression is a prevalent disorder with substantial morbidity and mortality. Current treatment interventions do not target relevant pathophysiology and are frequently ineffective, thereby leading to a substantial burden for individuals, families, and society. During adolescence, the prefrontal cortex undergoes extensive structural and functional changes. Recent work suggests that frontolimbic development in depressed adolescents is delayed or aberrant. The judicious application of non-invasive brain stimulation techniques to the prefrontal cortex may present a promising opportunity for durable interventions in adolescent depression. Transcranial direct current stimulation (tDCS applies a low-intensity, continuous current that alters cortical excitability. While this modality does not elicit action potentials, it is thought to manipulate neuronal activity and neuroplasticity. Specifically, tDCS may modulate N-methyl-d-aspartate receptors and L-type voltage-gated calcium channels and effect changes through long-term potentiation or long-term depression-like mechanisms. This mini-review considers the neurobiological rationale for developing tDCS protocols in adolescent depression, reviews existing work in adult mood disorders, surveys the existing tDCS literature in adolescent populations, reviews safety studies, and discusses distinct ethical considerations in work with adolescents.

  13. Research on Low Power Marine Current Power Generation System

    Directory of Open Access Journals (Sweden)

    Dongkai Peng

    2013-09-01

    Full Text Available This study proposes a simple topological structure and power control method for a small scale stand alone marine current system, in which a diode rectifier, DC/DC boost converter for the maximum power control, battery as a storage element and a single phase inverter to link with load. The study establishes the steady-state mathematical model of marine current power generation system and derives the formula between the maximum power point and dc battery voltage. Then use the measurements of DC voltage and DC current to obtain Maximum Power Point Tracking (MPPT by controlling the duty cycle of the boost converter switch in order to simplify the system structure and the control strategies. In this case, the hill climbing searching algorithm is employed to get maximum power point and the double closed loops control strategy is used to improve the dynamic and static performance of single phase inverter. The simulation model is developed in MATLAB/Simulink. And the control method is executed in dSPACE1104 real-time platform. The simulation and experimental results demonstrate the feasibility and validity of the proposed control strategies.

  14. Artificial Neural Networks in Policy Research: A Current Assessment.

    Science.gov (United States)

    Woelfel, Joseph

    1993-01-01

    Suggests that artificial neural networks (ANNs) exhibit properties that promise usefulness for policy researchers. Notes that ANNs have found extensive use in areas once reserved for multivariate statistical programs such as regression and multiple classification analysis and are developing an extensive community of advocates for processing text…

  15. Talent management : Current theories and future research directions

    NARCIS (Netherlands)

    Al Ariss, A.; Cascio, W.F.; Paauwe, J.

    2014-01-01

    Research on Talent Management (TM) has been lagging behind businesses in offering vision and leadership in this field. After sketching a comprehensive outline of knowledge about TM, theoretical as well as practical, we introduce the papers in this special issue and their important contributions.

  16. Applying Current Theory and Research in Career Exploration to Practice.

    Science.gov (United States)

    Blustein, David L.

    1992-01-01

    Provides selected review of two lines of recent research on career exploration (identifying antecedents of exploratory activity and application of information processes biases to career exploration), with specific focus on applications for counseling practice. Describes relevant counseling interventions and concludes with summary of six goals to…

  17. Current research in transcultural psychiatry in the Nordic countries.

    Science.gov (United States)

    Ekblad, Solvig; Kastrup, Marianne Carisius

    2013-12-01

    This article discusses major themes in recent transcultural psychiatric research in the Nordic countries from 2008 to 2011: (a) epidemiological studies of migration, (b) indigenous populations, and (c) quality of psychiatric care for migrants. Over the past several decades, the populations of the Nordic countries, Denmark, Finland, Norway, and Sweden, which were relatively homogeneous, have become increasingly culturally diverse. Many migrants to Nordic countries have been exposed to extreme stress, such as threats of death and/or torture and other severe social adversities before, during, and after migration, with potential effects on their physical, mental, social, and spiritual health. Growing interest in transcultural issues is reflected in the level of scientific research and clinical activity in the field by Nordic physicians, psychologists, social scientists, demographers, medical anthropologists, as well as other clinicians and policy planners. Research includes work with migrants and indigenous minorities in the Nordic countries, as well as comparisons with mental health in postconflict countries. We conclude by suggesting future directions for transcultural psychiatry research and providing guidelines for the education and training of future clinicians in the Nordic countries.

  18. Gifted Male Readers: Current Understandings and Suggestions for Future Research

    Science.gov (United States)

    Pagnani, Alexander R.

    2013-01-01

    Research literature concerning gifted male readers relies primarily on more extensive bodies of work regarding gifted males and male readers. Studied as a whole, the two halves portray a worrisome state of affairs for gifted male readers, who lag behind their female counterparts in the same patterns found across the ability spectrum. This literacy…

  19. Current Research and Opportunities to Address Environmental Asbestos Exposures

    Science.gov (United States)

    Asbestos-related diseases continue to result in approximately 120,000 deaths every year in the United States and worldwide.Although extensive research has been conducted on health effects of occupational exposures to asbestos, many issues related to environmental asbestos exposur...

  20. Behavioral Marital Therapy: Current Trends in Research, Assessment and Practice.

    Science.gov (United States)

    Jacobson, Neil S.

    1980-01-01

    Behavioral Marital Therapy (BMT) is clinically useful because it includes elaborating procedures, modifying the spouse's self-defeating cognitions, and moving toward early intervention and prevention. Each article in this issue of American Journal of Family Therapy focuses on innovations in BMT, either in research or practice. (Author/NRB)

  1. Dyslexia and the Brain: What Does Current Research Tell Us?

    Science.gov (United States)

    Hudson, Roxanne F.; High, Leslie; Al Otaiba, Stephanie

    2007-01-01

    Dyslexia is a disorder of the language-processing systems in the brain. It is a specific learning disability in reading that often affects spelling as well. This article describes: (1) Common characteristics experienced by people with dyslexia or reading disabilities; (2) Common misconceptions about dyslexia; (3) What brain research tell us about…

  2. Current Relevance of Zetetics to Library Research and Library Instruction.

    Science.gov (United States)

    Davis, Marta A.; Davis, Harry O.

    1996-01-01

    Explains zetetics which involve theories of research and epistemology and discusses its relevance to library science. Topics include library literacy, and the use of an information matrix to help library patrons understand what information they have and what they need to find. (Author/LRW)

  3. Materials for hydrogen storage: current research trends and perspectives.

    Science.gov (United States)

    van den Berg, Annemieke W C; Areán, Carlos Otero

    2008-02-14

    Storage and transport of hydrogen constitutes a key enabling technology for the advent of a hydrogen-based energy transition. Main research trends on hydrogen storage materials, including metal hydrides, porous adsorbents and hydrogen clathrates, are reviewed with a focus on recent developments and an appraisal of the challenges ahead. .

  4. Artificial Neural Networks in Policy Research: A Current Assessment.

    Science.gov (United States)

    Woelfel, Joseph

    1993-01-01

    Suggests that artificial neural networks (ANNs) exhibit properties that promise usefulness for policy researchers. Notes that ANNs have found extensive use in areas once reserved for multivariate statistical programs such as regression and multiple classification analysis and are developing an extensive community of advocates for processing text…

  5. Business model innovation: Past research, current debates, and future directions

    DEFF Research Database (Denmark)

    Hossain, Mokter

    2017-01-01

    Purpose – The purpose of this paper is to provide state-of-the-art knowledge about business model innovation (BMI) and suggest avenues for future research. Design/methodology/approach – A systematic literature review approach was adopted with thematic analysis being conducted on 92 articles...

  6. Current research in Spain on walnut for wood production

    Science.gov (United States)

    Neus Alet& #224; Neus NO-VALUE

    2004-01-01

    The Department of Mediterranean Trees at the Institut de Recerca i Tecnologia Agroalimentaries (IRTA) in Spain initiated a research program in 1993 to examine the variability among walnut species for wood production and to establish orchards with improved selections. The main objective of the programme is to obtain superior Persian walnut (Juglans regia...

  7. Current Research and Opportunities to Address Environmental Asbestos Exposures

    Science.gov (United States)

    Asbestos-related diseases continue to result in approximately 120,000 deaths every year in the United States and worldwide.Although extensive research has been conducted on health effects of occupational exposures to asbestos, many issues related to environmental asbestos exposur...

  8. Current and Planned Cochlear Implant Research at New York University Laboratory for Translational Auditory Research

    Science.gov (United States)

    Svirsky, Mario A.; Fitzgerald, Matthew B.; Neuman, Arlene; Sagi, Elad; Tan, Chin-Tuan; Ketten, Darlene; Martin, Brett

    2013-01-01

    The Laboratory of Translational Auditory Research (LTAR/NYUSM) is part of the Department of Otolaryngology at the New York University School of Medicine and has close ties to the New York University Cochlear Implant Center. LTAR investigators have expertise in multiple related disciplines including speech and hearing science, audiology, engineering, and physiology. The lines of research in the laboratory deal mostly with speech perception by hearing impaired listeners, and particularly those who use cochlear implants (CIs) or hearing aids (HAs). Although the laboratory's research interests are diverse, there are common threads that permeate and tie all of its work. In particular, a strong interest in translational research underlies even the most basic studies carried out in the laboratory. Another important element is the development of engineering and computational tools, which range from mathematical models of speech perception to software and hardware that bypass clinical speech processors and stimulate cochlear implants directly, to novel ways of analyzing clinical outcomes data. If the appropriate tool to conduct an important experiment does not exist, we may work to develop it, either in house or in collaboration with academic or industrial partners. Another notable characteristic of the laboratory is its interdisciplinary nature where, for example, an audiologistandan engineer might work closely to develop an approach that would not have been feasible if each had worked singly on the project. Similarly, investigators with expertise in hearing aids and cochlear implants might join forces to study how human listeners integrate information provided by a CI and a HA. The following pages provide a flavor of the diversity and the commonalities of our research interests. PMID:22668763

  9. Researches on regenerative medicine——current state and prospect

    Institute of Scientific and Technical Information of China (English)

    WANG Zheng-guo; XIAO Kai

    2012-01-01

    Since 1980s,the rapid development of tissue engineering and stem cell research has pushed regenerative medicine to a new fastigium,and regenerative medicine has become a noticeable research field in the international biology and medicine.In China,about 100 million patients need repair and regeneration treatment every year,while the number is much larger in the world.Regenerative medicine could provide effective salvation for these patients.Both Chinese Academy of Sciences and Chinese Academy of Engineering have made roadmaps of 2010-2050 and 2011-2030 for regenerative medicine.The final goal of the two roadmaps is to make China go up to leading position in most research aspects of regenerative medicine.In accord with this strategy,the government and some enterprises have invested 3-5 billion RMB (0.5-0.8 billion USD)for the research on regenerative medicine.In order to push the translation of regenerative medicine forward - from bench to bedside,a strategic alliance has been established.and it includes 27 top-level research institutes,medical institutes,colleges,universities and enterprises in the field of stem cell and regeneration medicine.Recently the journal,Science,has published a special issue-Regenerative Medicine in China,consisting of 35 papers dealing with stem cell and regeneration,tissue engineering and regeneration,trauma and regeneration and bases for tissue repair and regenerative medicine.It is predicated that a greater breakthrough in theory and practice of regenerative medicine will be achieved in the near future (20 to 30 years).

  10. An Investigation of the Intellectual Structure of Opinion Mining Research

    Science.gov (United States)

    Zhu, Yongjun; Kim, Meen Chul; Chen, Chaomei

    2017-01-01

    Introduction: Opinion mining has been receiving increasing attention from a broad range of scientific communities since early 2000s. The present study aims to systematically investigate the intellectual structure of opinion mining research. Method: Using topic search, citation expansion, and patent search, we collected 5,596 bibliographic records…

  11. Comprehensive Investigation on Current Imbalance among Parallel Chips inside MW-Scale IGBT Power Modules

    DEFF Research Database (Denmark)

    Wu, Rui; Smirnova, Liudmila; Wang, Huai

    2015-01-01

    With the demands for increasing the power rating and improving reliability level of the high power IGBT modules, there are further needs of understanding how to achieve stable paralleling and identical current sharing between the chips. This paper investigates the stray parameters imbalance among...... parallel chips inside the 1.7 kV/1 kA high power IGBT modules at different frequencies by Ansys Q3D parastics extractor. The resulted current imbalance is further confirmed by experimental measurement....

  12. Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research

    NARCIS (Netherlands)

    T. van Asselt (Thea); B.L.T. Ramaekers (Bram); I. Corro Ramos (Isaac); M.A. Joore (Manuela); M.J. Al (Maiwenn); Lesman-Leegte, I. (Ivonne); M.J. Postma (Maarten); P. Vemer (Pepijn); T.L. Feenstra (Talitha)

    2017-01-01

    textabstractBackground: The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. Objective: The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses;

  13. THEORETICAL INVESTIGATION ON BY-ONLY-CURRENT ELECTROMAGNETIC SEPARATION OF INCLUSION FROM MOLTEN METALS

    Institute of Scientific and Technical Information of China (English)

    B.W. Zhang; Z.M. Ren; Y.B. Zhong; K. Deng; K.D. Xu

    2002-01-01

    The electromagnetic field under applied AC and DC current in round and rectangularpipe was systematically investigated, then a concept of "equivalent current density"was proposed for evaluating the inhomogeneous electromagnetic pinch force, and themono-component removal efficiency and the overall removal efficiency of inclusionwere formulated. It is founded that flat pipe is superior to round pipe for the electro-magnetic removal of inclusion, and DC current can get a higher removal efficiencythan AC current due to absence of skin phenomenon. Under usual condition, a re-moval efficiency of 52% for 10μm inclusion or more than 92% for 20μm inclusioncan be achieved by imposing a current density of 3× 106A/m2 in a fiat pipe.

  14. Icing Branch Current Research Activities in Icing Physics

    Science.gov (United States)

    Vargas, Mario

    2009-01-01

    Current development: A grid block transformation scheme which allows the input of grids in arbitrary reference frames, the use of mirror planes, and grids with relative velocities has been developed. A simple ice crystal and sand particle bouncing scheme has been included. Added an SLD splashing model based on that developed by William Wright for the LEWICE 3.2.2 software. A new area based collection efficiency algorithm will be incorporated which calculates trajectories from inflow block boundaries to outflow block boundaries. This method will be used for calculating and passing collection efficiency data between blade rows for turbo-machinery calculations.

  15. Nanomaterials in Lubricants: An Industrial Perspective on Current Research

    Directory of Open Access Journals (Sweden)

    Boris Zhmud

    2013-11-01

    Full Text Available This paper presents an overview on the use of various classes of nanomaterials in lubricant formulations. The following classes of nanomaterials are considered: fullerenes, nanodiamonds, ultradispersed boric acid and polytetrafluoroethylene (PTFE. Current advances in using nanomaterials in engine oils, industrial lubricants and greases are discussed. Results of numerous studies combined with formulation experience of the authors strongly suggest that nanomaterials do indeed have potential for enhancing certain lubricant properties, yet there is a long way to go before balanced formulations are developed.

  16. Current Research and Development of Chemotherapeutic Agents for Melanoma

    Directory of Open Access Journals (Sweden)

    Kyaw Minn Hsan

    2010-04-01

    Full Text Available Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma.

  17. Conceptual knowledge representation: A cross-section of current research.

    Science.gov (United States)

    Rogers, Timothy T; Wolmetz, Michael

    2016-01-01

    How is conceptual knowledge encoded in the brain? This special issue of Cognitive Neuropsychology takes stock of current efforts to answer this question through a variety of methods and perspectives. Across this work, three questions recur, each fundamental to knowledge representation in the mind and brain. First, what are the elements of conceptual representation? Second, to what extent are conceptual representations embodied in sensory and motor systems? Third, how are conceptual representations shaped by context, especially linguistic context? In this introductory article we provide relevant background on these themes and introduce how they are addressed by our contributing authors.

  18. [Musculoskeletal shock wave therapy--current database of clinical research].

    Science.gov (United States)

    Rompe, J D; Buch, M; Gerdesmeyer, L; Haake, M; Loew, M; Maier, M; Heine, J

    2002-01-01

    During the past decade application of extracorporal shock waves became an established procedure for the treatment of various musculoskeletal diseases in Germany. Up to now the positive results of prospective randomised controlled trials have been published for the treatment of plantar fasciitis, lateral elbow epicondylitis (tennis elbow), and of calcifying tendinitis of the rotator cuff. Most recently, contradicting results of prospective randomised placebo-controlled trials with adequate sample size calculation have been reported. The goal of this review is to present information about the current clinical database on extracorporeal shock wave treatment (ESWT).

  19. Current research on drugs and vaccines for fighting bird flu.

    Science.gov (United States)

    Wiwanitkit, Viroj

    2007-12-01

    Bird flu, or avian flu, caused by the H5N1 virus, is of concern worldwide. The antiviral drugs oseltamivir and zanamivir have been used to treat human cases, and resistance has been reported. Studies on the molecular mechanisms of antiviral resistance are needed to understand the problem and to aid future drug development. Control of a major outbreak would require a vaccine, but current manufacturing technology is not adequate to support influenza vaccine production in the event of an avian influenza outbreak.

  20. Current electroconvulsive therapy practice and research in the geriatric population

    Science.gov (United States)

    Kerner, Nancy; Prudic, Joan

    2014-01-01

    SUMMARY Electroconvulsive therapy (ECT) is utilized worldwide for various severe and treatment-resistant psychiatric disorders. Research studies have shown that ECT is the most effective and rapid treatment available for elderly patients with depression, bipolar disorder and psychosis. For patients who suffer from intractable catatonia and neuroleptic malignant syndrome, ECT can be life saving. For elderly patients who cannot tolerate or respond poorly to medications and who are at a high risk for drug-induced toxicity or toxic drug interactions, ECT is the safest treatment option. Organic causes are frequently associated with late-life onset of neuropsychiatric conditions, such as parkinsonism, dementia and stroke. ECT has proven to be efficacious even when these conditions are present. During the next decade, research studies should focus on the use of ECT as a synergistic therapy, to enhance other biological and psychological treatments, and prevent symptom relapse and recurrence. PMID:24778709

  1. Opening the "black box" of current creativity research

    DEFF Research Database (Denmark)

    Hoffmann Birk, Rasmus; Ernø, Steffen

    value" or none at all. Creativity was mostly measured with different types of divergent thinking tests. There appears to be a lack of deeper theoretical and methodological discussions of creativity in the literature, which creates a disconnection between definitions, methodologies and the interpretation......This presentation aims to problematise the ways in which creativity is defined and measured in recent studies on the topic. For this purpose, we analyzed 58 articles on creativity, selected from within the sub-fields of neuropsychology, psychometrics and developmental psychology published from 2009......-2012. The sub-fields were chosen because of their prominence in psychological research and research on creativity. The articles were procured from the PsycINFO database, with selection criteria being that they must be peer-reviewed and empirical studies. Typical definitions of creativity were "novelty plus...

  2. CYBERQUEER – MAJOR TOPICS AND ISSUES IN CURRENT RESEARCH

    Directory of Open Access Journals (Sweden)

    SIMONA RODAT

    2014-12-01

    Full Text Available The emergence of the opportunities opened by the internet raises also questions of interest for research regarding the extent to which these have an impact on the formations of non heterosexual life and on the experience of marginalised sexual identities. There have been different approaches in this regard and answers vary from optimistic and utopian appraisals concerning cyberspace in the early 90s to the more moderate and sceptic visions in the 2000s. Starting from this framework of debates, the present paper aims to explore the meaning of the term “cyberqueer”, including the theoretical context of its occurrence, to briefly highlight some critical considerations relating to cyberqueer research and to look over the main recurrent themes linked up with this concept, such as queer and cyberqueer identity, body and (disembodied practices and the forthcoming process of blurring the dividing boundaries between real/virtual, online/offline and public/private

  3. AAS Nova and Astrobites: Making current astronomy research accessible

    Science.gov (United States)

    Kohler, Susanna; Astrobites Team

    2016-10-01

    AAS Nova and Astrobites are two resources available for astronomers, astronomy students, and astronomy enthusiasts to keep up with some of the most recent research published across the field of astronomy. Both supported by the AAS, these two daily astrophysical literature blogs provide accessible summaries of recent publications on the arXiv and in AAS journals. We present the goals, content, and readership of AAS Nova and Astrobites, and discuss how they might be used as tools in the undergraduate classroom.

  4. Current Status and Trend of Forest Hydrological Services Market Research

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Of the many services that forests provide, hydrological services are among the most valuable, and it becomes more scarce with the growing demands by human beings. As a kind of incentive measure for protecting forest, forest hydrological services markets have been developed in many countries around the world and some valuable experiences have been achieved. The paper reviews the experiments carried out in the world and their research findings on forest hydrological services market, and presents the issues to...

  5. Ubiquitous Wireless Computing: Current Research Progress, Challenging, and Future Directions

    OpenAIRE

    Elyas, Palantei

    2014-01-01

    - The aggressive research activities and generous studies focusing on the ubiquitous mobile computing carried-out during the last two decades have gained very tremendous outcomes to apply in broad areas of modern society lives. In the near future, the computing technology application is highly possible to emerge as the dominant method to connect any objects to the global ICT infrastructure, the internet. This talk mainly discusses several R&D achievements performed during the last five yea...

  6. Current Institutional Trends in Research Productivity in Counseling Psychology Journals

    Science.gov (United States)

    Diegelman, Nathan M.; Uffelman, Rachel A.; Wagner, Kimberly S.; Diegelman, Sally A.

    2005-01-01

    This study investigated institutional publication activity in counseling psychology journals for the 10-year period from 1993 to 2002. Four journals reported by counseling psychology training directors as prime publication outlets for the field of counseling psychology were used: "Journal of Counseling Psychology," "The Counseling Psychologist,"…

  7. Music therapy in cardiac health care: current issues in research.

    Science.gov (United States)

    Hanser, Suzanne B

    2014-01-01

    Music therapy is a service that has become more prevalent as an adjunct to medical practice-as its evidence base expands and music therapists begin to join the cardiology team in every phase of care, from the most serious cases to those maintaining good heart health. Although applications of music medicine, primarily listening to short segments of music, are capable of stabilizing vital signs and managing symptoms in the short-term, music therapy interventions by a qualified practitioner are showing promise in establishing deeper and more lasting impact. On the basis of mind-body approaches, stress/coping models, the neuromatrix theory of pain, and entrainment, music therapy capitalizes on the ability of music to affect the autonomic nervous system. Although only a limited number of randomized controlled trials pinpoint the efficacy of specific music therapy interventions, qualitative research reveals some profound outcomes in certain individuals. A depth of understanding related to the experience of living with a cardiovascular disease can be gained through music therapy approaches such as nonverbal music psychotherapy and guided imagery and music. The multifaceted nature of musical responsiveness contributes to strong individual variability and must be taken into account in the development of research protocols for future music therapy and music medicine interventions. The extant research provides a foundation for exploring the many potential psychosocial, physiological, and spiritual outcomes of a music therapy service for cardiology patients.

  8. The Communication Research in Spain. Historical evolution and current challenges

    Directory of Open Access Journals (Sweden)

    Dr. Manuel Martínez Nicolás - manuel.martinez.nicolas@urjc.es

    2009-01-01

    Full Text Available We propose in this paper an approach to the history of Communication Research in Spain, taking into account the scientific production and the structure and historical context in which the scientific community interested in this field have performed their work. For this task we have established a temporary frame beginning from the moment communication became an autonomous field of research and education in Spain, during the mid-sixties, until present time. This period has been divided into three stages, typically defined as emergence, consolidation and development (or maturing of communication studies in Spain. In each of these stages, the scientific community interested in communication research have worked in different social, academic and epistemic or scientific contexts. These particular conditions contribute to understanding the different orientations which have inspired historical communication research in Spain (research objects, theoretical and methodological approaches, contributions and limitations.Traducción supervisada por la Dda. María Teresa Durán Sánchez (ULPGC.En este trabajo se propone una aproximación a la historia de la investigación sobre comunicación en España poniendo en relación la producción científica con las características, estructura y condiciones históricas en las que ha desempeñado su trabajo la comunidad científica interesada en este ámbito. Para ello, se establece un marco temporal que arranca en el momento de la constitución de la comunicación como campo de investigación (y de docencia autónomo, a mediados de la década de los sesenta, y llega hasta la actualidad. Consideramos que en el curso de este periodo pueden distinguirse no menos de tres etapas, que convencionalmente se han denominado de emergencia, consolidación y desarrollo (o maduración de los estudios sobre comunicación en España. En cada una de estas etapas, la comunidad científica interesada en la investigación comunicativa

  9. Reprioritizing current research trends in medical education: a reflection on research activities in Saudi Arabia.

    Science.gov (United States)

    Obeidat, Akef S; Alhaqwi, Ali Ibrahim; Abdulghani, Hamza Mohammad

    2015-04-01

    There are numerous national efforts to determine and develop research priorities of medical education in Saudi Arabia. These priorities were first proposed in 2010 by "Dr Al-Khuli's Chair for Developing Medical Education in Saudi Arabia". The proposed priority domains were: curriculum, students, faculty, and quality assurance and accreditation. To investigate publications in medical education at the national and international levels in areas relating to these proposed priorities. Electronic search within PubMed database for papers relating to each domain of priority was conducted at national and international levels in the last three years, using the same keywords as the priority domains, but only confined to undergraduate medical education. Out of 3145 articles retrieved when searching with keyword as broad as "undergraduate medical curriculum" only 81 articles worldwide and 3 articles from Saudi Arabia were dealing with curriculum related issues as a whole. Further search on the sub-domains "effective strategies to manage undergraduate curriculum" and "undergraduate medical education models", resulted in the retrieval of few articles worldwide and none from Saudi Arabia. At the national level, there were 63 publications from Saudi Arabia that were either course (topic)-specific or could not be classified under the four domains specified by Dr Al-Khuli's Chair. Research activities in medical education in Saudi Arabia in the last 3 years showed diversity and lack of focus in the research priorities. Efforts of academic and research centers should continue to monitor and encourage these activities toward achieving the recommended priorities.

  10. Alaskan Peninsula Cenozoic stratigraphy: stratigraphic sequences and current research

    Energy Technology Data Exchange (ETDEWEB)

    Allison, R.C.; Armentrout, J.M.

    1985-04-01

    Geology of the Alaska Peninsula-Island Arc and Continental Margin, by C.A. Burk, is the principal reference for stratigraphic studies on the Alaska Peninsula. Burk mapped the Phanerozoic stratigraphy and provided a geologic history and structural interpretation of the area between Wide Bay and Unimak Island. Cenozoic rocks were mapped as three unconformity-bounded sequences. Recognition of specific formations was difficult due to similarity of lithofacies, isolated outcrops, rapid facies changes, and alteration and burial by young volcanics. Consequently, megafossil assemblages were relied upon to facilitate correlations between study areas. The three unconformity-bounded Cenozoic sequences are: (1) the Paleogene Beaver Bay Group consisting of three formations: the dominantly nonmarine Tolstoi Formation, the dominantly marine Stepovak Formation, and the volcanic Meshik Formation. Current work suggests these units are at least in part coeval facies of late Paleocene through Oligocene age. (2) The Neogene Bear Lake Formation consisting of the lower Unga Conglomerate Member and an unnamed upper member. Rapid facies changes and incorrect reports of fossil occurrence have resulted in confusion of stratigraphic relationships within this sequence of middle to late Miocene age. (3) A late Neogene informally defined upper sequence consisting of interbedded marginal marine, coastal-plain, and volcanic facies. Current work suggests this sequence is Pliocene through Pleistocene in age.

  11. Science and cycling: current knowledge and future directions for research.

    Science.gov (United States)

    Atkinson, Greg; Davison, Richard; Jeukendrup, Asker; Passfield, Louis

    2003-09-01

    In this holistic review of cycling science, the objectives are: (1) to identify the various human and environmental factors that influence cycling power output and velocity; (2) to discuss, with the aid of a schematic model, the often complex interrelationships between these factors; and (3) to suggest future directions for research to help clarify how cycling performance can be optimized, given different race disciplines, environments and riders. Most successful cyclists, irrespective of the race discipline, have a high maximal aerobic power output measured from an incremental test, and an ability to work at relatively high power outputs for long periods. The relationship between these characteristics and inherent physiological factors such as muscle capilliarization and muscle fibre type is complicated by inter-individual differences in selecting cadence for different race conditions. More research is needed on high-class professional riders, since they probably represent the pinnacle of natural selection for, and physiological adaptation to, endurance exercise. Recent advances in mathematical modelling and bicycle-mounted strain gauges, which can measure power directly in races, are starting to help unravel the interrelationships between the various resistive forces on the bicycle (e.g. air and rolling resistance, gravity). Interventions on rider position to optimize aerodynamics should also consider the impact on power output of the rider. All-terrain bicycle (ATB) racing is a neglected discipline in terms of the characterization of power outputs in race conditions and the modelling of the effects of the different design of bicycle frame and components on the magnitude of resistive forces. A direct application of mathematical models of cycling velocity has been in identifying optimal pacing strategies for different race conditions. Such data should, nevertheless, be considered alongside physiological optimization of power output in a race. An even distribution

  12. Ecosystem services – current challenges and opportunities for ecological research

    Directory of Open Access Journals (Sweden)

    Klaus eBirkhofer

    2015-01-01

    Full Text Available The concept of ecosystem services was originally developed to illustrate the benefits that natural ecosystems generate for society and to raise awareness for biodiversity and ecosystem conservation. In this article we identify major challenges and opportunities for ecologists involved in empirical or modeling ecosystem service research. The first challenge arises from the fact that the ecosystem service concept has not been generated in the context of managed systems. Ecologists need to identify the effect of anthropogenic interventions in order to propose practices to benefit service-providing organisms and associated services. The second challenge arises from the need to evaluate relationships between indicators of ecosystem services that are collected in ecological studies while accounting for uncertainties of ecological processes that underlie these services. We suggest basing the assessment of ecosystem services on the utilization of sets of indicators that cover aspects of service-providing units, ecosystem management and landscape modification. The third challenge arises from our limited understanding of the nature of relationships between services and a lack of a general statistical framework to address these links. To manage ecosystem service provisioning, ecologists need to establish whether services respond to a shared driver or if services are directly linked to each other. Finally, studies relating biodiversity to ecosystem services often focus on services at small spatial or short temporal scales, but research on the protection of services is often directed towards services providing benefits at large spatial scales. Ecological research needs to address a range of spatial and temporal scales to provide a multifaceted understanding of how nature promotes human well-being. Addressing these challenges in the future offers a unique opportunity for ecologists to act as promoters for the understanding about how to conserve benefits

  13. Current status of neutron activation analysis in HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong Sam; Moon, Jong Hwa; Sohn, Jae Min [Korea Atomic Energy Research Institute, Daejeon (Korea)

    2003-03-01

    The facilities for neutron activation analysis in the HANARO (Hi-flux Advanced Neutron Application Research Reactor) are described and the main applications of NAA (Neutron Activation Analysis) are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system were installed at three irradiation holes of HANARO at the end of 1995. The performance of the NAA facility was examined to identify the characteristics of the tube transfer system, irradiation sites and custom-made polyethylene irradiation capsule. The available thermal neutron fluxes at irradiation sites are in the range of 3 x 10{sup 13} - 1 x 10{sup 14} n/cm{sup 2}{center_dot}s and cadmium ratios are in 15 - 250. For an automatic sample changer for gamma-ray counting, a domestic product was designed and manufactured. An integrated computer program (Labview) to analyse the content was developed. In 2001, PGNAA (Prompt Gamma Neutron Activation Analysis) facility has been installed using a diffracted neutron beam of ST1. NAA has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials, and various polymers for research and development. The improvement of analytical procedures and establishment of an analytical quality control and assurance system were studied. Applied research and development for the environment, industry and human health by NAA and its standardization were carried out. For the application of the KOLAS (Korea Laboratory Accreditation Scheme), evaluation of measurement uncertainty and proficiency testing of reference materials were performed. Also to verify the reliability and to validate analytical results, intercomparison studies between laboratories were carried out. (author)

  14. Current Research in Aircraft Tire Design and Performance

    Science.gov (United States)

    Tanner, J. A.; Mccarthy, J. L.; Clark, S. K.

    1981-01-01

    A review of the tire research programs which address the various needs identified by landing gear designers and airplane users is presented. The experimental programs are designed to increase tire tread lifetimes, relate static and dynamic tire properties, establish the tire hydroplaning spin up speed, study gear response to tire failures, and define tire temperature profiles during taxi, braking, and cornering operations. The analytical programs are aimed at providing insights into the mechanisms of heat generation in rolling tires and developing the tools necessary to streamline the tire design process and to aid in the analysis of landing gear problems.

  15. Current Status of Dengue Therapeutics Research and Development.

    Science.gov (United States)

    Low, Jenny G H; Ooi, Eng Eong; Vasudevan, Subhash G

    2017-03-01

    Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of dengue. This review will provide a brief account of the status of therapeutics research and development for dengue. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.

  16. Current status, research progress and future plan of Kartini research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sardjono, Y.; Syarip; Tjiptono, T.W. [Yogyakarta Nuclear Research Center, Batan (Indonesia)

    1999-10-01

    The current status, research progress and future plan of the Kartini Research Reactor (KRR) is presented. The measurements of axial burn-up distributions for each fuel element by gamma scanning techniques, core axial power distribution display, fuel management for safeguards purpose as well as some research progress activities i.e.; utilization of beamport for: neutron radiography, application neutron activation analysis and history record of KRR power operations is also presented. The KRR is 100 kW pool water reactor type which uses natural circulation and provided by: five beamports in which one of them already coupled with natural uranium subcritical assembly, two thermalizing columns in which one of them is prepared for developing Boron Neutron Capture Therapy (BNCT), two rabbit systems utilized for special analysis uranium ore by delayed neutron counting techniques, one center timbre and 40 irradiation rack (lazy susan) for neutron activation analysis. The KRR was constructed as a second research reactor in Indonesia with special purpose for training and education, high safety margin with involve in high negative temperature coefficient which achieved its first criticality on January 25, 1979. The maximum power level on first criticality is 50 kW and since August 1981 up to now is operating 100 kW. Base on the KRR design limit, it is planned to increase the power level up to 250 kW in the future plan. The preliminary activities such as Non Destructive Testing (NDT) for some reactor components especially water tank and thermal column should be done before decided to increase power level. (author)

  17. JSC Advanced Curation: Research and Development for Current Collections and Future Sample Return Mission Demands

    Science.gov (United States)

    Fries, M. D.; Allen, C. C.; Calaway, M. J.; Evans, C. A.; Stansbery, E. K.

    2015-01-01

    Curation of NASA's astromaterials sample collections is a demanding and evolving activity that supports valuable science from NASA missions for generations, long after the samples are returned to Earth. For example, NASA continues to loan hundreds of Apollo program samples to investigators every year and those samples are often analyzed using instruments that did not exist at the time of the Apollo missions themselves. The samples are curated in a manner that minimizes overall contamination, enabling clean, new high-sensitivity measurements and new science results over 40 years after their return to Earth. As our exploration of the Solar System progresses, upcoming and future NASA sample return missions will return new samples with stringent contamination control, sample environmental control, and Planetary Protection requirements. Therefore, an essential element of a healthy astromaterials curation program is a research and development (R&D) effort that characterizes and employs new technologies to maintain current collections and enable new missions - an Advanced Curation effort. JSC's Astromaterials Acquisition & Curation Office is continually performing Advanced Curation research, identifying and defining knowledge gaps about research, development, and validation/verification topics that are critical to support current and future NASA astromaterials sample collections. The following are highlighted knowledge gaps and research opportunities.

  18. 76 FR 38399 - Assessing the Current Research, Policy, and Practice Environment in Public Health Genomics

    Science.gov (United States)

    2011-06-30

    ... HUMAN SERVICES Centers for Disease Control and Prevention Assessing the Current Research, Policy, and..., and other information helpful to assess the current research, policy, and practice environment in... Control and Prevention (CDC) has worked to integrate genomics into public health research, policy,...

  19. Strength and conditioning in tennis: current research and practice.

    Science.gov (United States)

    Reid, Machar; Schneiker, Knut

    2008-06-01

    Virtually all professional tennis players are in continuous pursuit of enhanced performance. With the modern game becoming increasingly dynamic and tournament schedules no less demanding, the importance of physical fitness is well accepted. Indeed, most professional tennis players resource strength and conditioning specialists on a full- or part-time basis. As tennis play is characterised by intricate bio-energetics, planning specific strength and conditioning interventions represents a significant challenge for the specialist. Further, where game physiology and mechanics have been described extensively, critiques of the efficacy of different training initiatives are far less common. This review therefore considers the current scientific, tennis-specific fitness training evidence base in light of contemporary conditioning, and more particularly resistance training, practices.

  20. Caffeine and cardiovascular diseases: critical review of current research.

    Science.gov (United States)

    Zulli, Anthony; Smith, Renee M; Kubatka, Peter; Novak, Jan; Uehara, Yoshio; Loftus, Hayley; Qaradakhi, Tawar; Pohanka, Miroslav; Kobyliak, Nazarii; Zagatina, Angela; Klimas, Jan; Hayes, Alan; La Rocca, Giampiero; Soucek, Miroslav; Kruzliak, Peter

    2016-06-01

    Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains "Which dose is safe?", as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.

  1. [Organ cryopreservation: current status of research carried out in Grenoble].

    Science.gov (United States)

    Descotes, J L; Payen, E; Rambeaud, J J; Peuridieu, J F; Baudot, A; Odin, J; Mazuer, J; Boutron, P; Delon-Martin, C; Dupeyre, R

    1995-12-01

    After discussing the problem of organ cryopreservation and reviewing the current data available on this subject, the Grenoble project is presented. Physical and biological studies have been combined with experimentation of autologous renal transplantation in rabbits to assess the functional value of the retransplanted organ after treatment and cooling. Renal resistances are measured during perfusion of the kidney with the cryoprotective solution. In order to verify the homogeneity of the cryoprotector concentration in the organ, on NMR spectral imaging test has been developed. A new rapid imaging method now allows real time monitoring of concentration variations during perfusion. In addition to concentration and homogeneity, analysis of local spectra also provides information about the local temperature de the kidney.

  2. The Development and Current State of Translation Process Research

    DEFF Research Database (Denmark)

    Lykke Jakobsen, Arnt

    2014-01-01

    which simultaneously tracks the translator’s eye movements across a screen displaying both a source text and the translator’s emerging translation. This research method was developed as a means of qualifying and strengthening translation process hypotheses based on verbal reports by providing additional...... remains inaccessible to outside observation. What mental processes underlie measurable (micro)behaviour can only be inferred. A multi-methodological approach is clearly called for in order to capture the full complexity of translation, and translation studies must be open to extend its curiosity beyond...... itself, into regions like cognitive psychology, psycho- and neurolinguistics, and neuroscience, where the interest in what goes on in our heads is also very strong....

  3. Microarrays—Current and Future Applications in Biomedical Research

    Directory of Open Access Journals (Sweden)

    Ulrich Certa

    2011-11-01

    Full Text Available Microarrays covers research where microarrays are applied to address complex biological questions. This new open access journal publishes articles where novel applications or state-of-the art technology developments in the field are reported. In addition, novel methods or data analysis algorithms are under the scope of Microarrays. This journal will serve as a platform for fast and efficient sharing of data within this large user community. As one of the first microarray users in Europe back in 1996, I am proud to serve as Editor-in-Chief and I believe we have assembled a highly proficient Editorial Board, responsible for a fair and fast peer-review of articles.

  4. Current Status of Japanese Global Precipitation Measurement (GPM) Research Project

    Science.gov (United States)

    Kachi, Misako; Oki, Riko; Kubota, Takuji; Masaki, Takeshi; Kida, Satoshi; Iguchi, Toshio; Nakamura, Kenji; Takayabu, Yukari N.

    2013-04-01

    The Global Precipitation Measurement (GPM) mission is a mission led by the Japan Aerospace Exploration Agency (JAXA) and the National Aeronautics and Space Administration (NASA) under collaboration with many international partners, who will provide constellation of satellites carrying microwave radiometer instruments. The GPM Core Observatory, which carries the Dual-frequency Precipitation Radar (DPR) developed by JAXA and the National Institute of Information and Communications Technology (NICT), and the GPM Microwave Imager (GMI) developed by NASA. The GPM Core Observatory is scheduled to be launched in early 2014. JAXA also provides the Global Change Observation Mission (GCOM) 1st - Water (GCOM-W1) named "SHIZUKU," as one of constellation satellites. The SHIZUKU satellite was launched in 18 May, 2012 from JAXA's Tanegashima Space Center, and public data release of the Advanced Microwave Scanning Radiometer 2 (AMSR2) on board the SHIZUKU satellite was planned that Level 1 products in January 2013, and Level 2 products including precipitation in May 2013. The Japanese GPM research project conducts scientific activities on algorithm development, ground validation, application research including production of research products. In addition, we promote collaboration studies in Japan and Asian countries, and public relations activities to extend potential users of satellite precipitation products. In pre-launch phase, most of our activities are focused on the algorithm development and the ground validation related to the algorithm development. As the GPM standard products, JAXA develops the DPR Level 1 algorithm, and the NASA-JAXA Joint Algorithm Team develops the DPR Level 2 and the DPR-GMI combined Level2 algorithms. JAXA also develops the Global Rainfall Map product as national product to distribute hourly and 0.1-degree horizontal resolution rainfall map. All standard algorithms including Japan-US joint algorithm will be reviewed by the Japan-US Joint

  5. Plasma medicine—current state of research and medical application

    Science.gov (United States)

    Weltmann, K.-D.; von Woedtke, Th

    2017-01-01

    Plasma medicine means the direct application of cold atmospheric plasma (CAP) on or in the human body for therapeutic purposes. Further, the field interacts strongly with results gained for biological decontamination. Experimental research as well as first practical application is realized using two basic principles of CAP sources: dielectric barrier discharges (DBD) and atmospheric pressure plasma jets (APPJ). Originating from the fundamental insights that the biological effects of CAP are most probably caused by changes of the liquid environment of cells, and are dominated by reactive oxygen and nitrogen species (ROS, RNS), basic mechanisms of biological plasma activity are identified. It was demonstrated that there is no increased risk of cold plasma application and, above all, there are no indications for genotoxic effects. The most important biological effects of cold atmospheric pressure plasma were identified: (1) inactivation of a broad spectrum of microorganisms including multidrug resistant ones; (2) stimulation of cell proliferation and tissue regeneration with lower plasma treatment intensity (treatment time); (3) inactivation of cells by initialization of programmed cell death (apoptosis) with higher plasma treatment intensity (treatment time). In recent years, the main focus of clinical applications was in the field of wound healing and treatment of infective skin diseases. First CAP sources are CE-certified as medical devices now which is the main precondition to start the introduction of plasma medicine into clinical reality. Plasma application in dentistry and, above all, CAP use for cancer treatment are becoming more and more important research fields in plasma medicine. A further in-depth knowledge of control and adaptation of plasma parameters and plasma geometries is needed to obtain suitable and reliable plasma sources for the different therapeutic indications and to open up new fields of medical application.

  6. Investigation of the Critical Current Density of YBaCuO high-temperature Superconductor Ceramic

    OpenAIRE

    METSKHVARISHVILI, I. R.; KEKELIDZE, N. P.; METSKHVARISHVILI, M. R.

    2002-01-01

    The method of high harmonics is used to investigate penetration of low magnetic fields within the Y1Ba2Cu3O7 high-temperature superconductor ceramic. Given experimental results are explained by the modal dependencies between the value of critical current density and the magnetic induction B: jc(B) = jc(0){\\frac{{B02}} {{B02 + B2}}}.

  7. Investigation of Leakage Current Waveforms Recorded in a Coastal High Voltage Substation

    Directory of Open Access Journals (Sweden)

    E. Thalassinakis

    2011-06-01

    Full Text Available Leakage current monitoring is a widely employed technique to monitor the performance of outdoor insulation. The evaluation of leakage current waveforms recorded in the field, offers significant information since insulation’s performance is strongly linked with local conditions, and the waveforms’ shape correlate to different types of surface activity. In this paper, an investigation of leakage current waveforms recorded in a 150 kV coastal Substations suffering which suffers intense marine pollution is presented. Investigation of the recorded waveforms verified the basic waveform shapes described in the literature. Further, several variations of the basic types and complex waveforms, as well as field related waveforms, are presented. The need for added categorization criteria in the case of field measurements is discussed.

  8. Research on Field Emission and Dark Current in ILC Cavities

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Kexin; Li, Yongming; Palczewski, Ari; Geng, Rongli

    2013-09-01

    Field emission and dark current are issues of concern for SRF cavity performance and SRF linac operation. Complete understanding and reliable control of the issue are still needed, especially in full-scale multi-cell cavities. Our work aims at developing a generic procedure for finding an active field emitter in a multi-cell cavity and benchmarking the procedure through cavity vertical test. Our ultimate goal is to provide feedback to cavity preparation and cavity string assembly in order to reduce or eliminate filed emission in SRF cavities. Systematic analysis of behaviors of field emitted electrons is obtained by ACE3P developed by SLAC. Experimental benchmark of the procedure was carried out in a 9-cell cavity vertical test at JLab. The energy spectrum of Bremsstrahlung X-rays is measured using a NaI(Tl) detector. The end-point energy in the X-ray energy spectrum is taken as the highest kinetic electron energy to predict longitudinal position of the active field emitter. Angular location of the field emitter is determined by an array of silicon diodes around irises of the cavity. High-resolution optical inspection was conducted at the predicted field emitter location.

  9. Experimental Investigation of a Direct Methanol Fuel Cell with Hilbert Fractal Current Collectors

    Directory of Open Access Journals (Sweden)

    Jing-Yi Chang

    2014-01-01

    Full Text Available The Hilbert curve is a continuous type of fractal space-filling curve. This fractal curve visits every point in a square grid with a size of 2×2, 4×4, or any other power of two. This paper presents Hilbert fractal curve application to direct methanol fuel cell (DMFC current collectors. The current collectors are carved following first, second, and third order Hilbert fractal curves. These curves give the current collectors different free open ratios and opening perimeters. We conducted an experimental investigation into DMFC performance as a function of the free open ratio and opening perimeter on the bipolar plates. Nyquist plots of the bipolar plates are made and compared using electrochemical impedance spectroscopy (EIS experiments to understand the phenomena in depth. The results obtained in this paper could be a good reference for future current collector design.

  10. An analytical investigation on singularity of current distribution around a crack in a long cylindrical superconductor

    Science.gov (United States)

    Xue, Feng; Zhou, You-He

    2010-06-01

    This paper presents an analytical investigation to display the distribution of critical current flow and trapped magnetic field around a through crack centrally located in a long cylindrical superconductor on the basis of the Bean model and the Kim model. After a simple conformal mapping is employed to the case of that the superconductor is fully penetrated, the current streamlines, the current density, and the trapped field around the crack in the superconductor without deformation are obtained. It is shown that the crack results in a long-range disturbance of J(r ) on the scale much larger than the crack length 2a and a large stagnation region of magnetic flux near the crack except for the singularity of the critical current at the crack tip. Meanwhile, it is also found that the singularity feature is different from the conventional stress one at the crack tip in a deformable body.

  11. [Deep brain stimulation: a review on current research].

    Science.gov (United States)

    Conca, Andreas; Di Pauli, Jan; Hinterhuber, Hartmann; Kapfhammer, Hans-Peter

    2011-01-01

    Recently Deep brain stimulation (DBS) has found continuous use in treatment of neurological movement disorders. However DBS in psychiatric illnesses is less investigated. Its application in depression, obsessive-compulsive disorder, and therapy-resistant Tourette- Syndrome shows positive effects and offers an advanced alternative to neurosurgical therapies of the past. There are also case reports suggesting therapeutic benefits in schizophrenia and addiction. To a large extent, the mechanisms of action appear to be still unknown; the side effects seem partially modulated through the stimulation parameters. Furthermore, some ethics committees argue that DBS exhibits a relevant impact on the personality. The novel approach as well as the unknown long term effects of DBS implicate that the technique can be performed only under strict individual diagnosis and rigorous consideration of all ethical concerns.

  12. Current Developments in Research on the Teaching of Grammar

    Institute of Scientific and Technical Information of China (English)

    Hossein Nassaji; Sandra Fotos

    2006-01-01

    @@ Continued from Issue 61 Textual Enhancement There are a number of studies that have investigated the effects of textual enhancement on drawing the learner's attention to grammar, and the method has been described as the least explicit and the least intrusive method of focus on form (Doughty & Varela, 1998). It involves highlighting certain features of input that might go unnoticed under normal circumstances by typographically manipulating them through boldfacing, italicizing, underlining, or capitalizing. The assumption is that such manipulations enhance the perceptual saliency of the target structures, and this, hence, increases their chance of being noticed. A related technique is the provision of numerous instances of target linguistic forms in the input, called an input flood (Trahey & While, 1993). Again,the assumption is that frequent exposure to target items enhances their saliency and hence results in noticing the forms (Schmidt, 1990; Sharwood Smith, 1993). Whereas studies by Doughty (1991) and Fotos (1994) reported positive results in terms of awareness of target structures and proficiency gains resulting from textually enhanced structures, a study by White (1998) did not show that learners who received textually enhanced input differed significantly in their ability to use the target structure compared with those who did not.White concluded that the method of enhancement may not have been sufficiently explicit to draw the learners' attention to the type of linguistic features that involved L1-L2 contrasts. Similarly, Leow (2001) investigated the effects of textual enhancement on learning Spanish formal imperatives and found no advantage for enhanced text over unenhanced text.Finally, Izumi (2001) compared two types of focus on form strategies, output and visual input enhancement, on the learning of English relativization by adult ESL learners, finding that those who produced output developed more than those merely received input. However, the visual

  13. Current trends and future directions in flower development research.

    Science.gov (United States)

    Scutt, Charlie P; Vandenbussche, Michiel

    2014-11-01

    Flowers, the reproductive structures of the approximately 400 000 extant species of flowering plants, exist in a tremendous range of forms and sizes, mainly due to developmental differences involving the number, arrangement, size and form of the floral organs of which they consist. However, this tremendous diversity is underpinned by a surprisingly robust basic floral structure in which a central group of carpels forms on an axis of determinate growth, almost invariably surrounded by two successive zones containing stamens and perianth organs, respectively. Over the last 25 years, remarkable progress has been achieved in describing the molecular mechanisms that control almost all aspects of flower development, from the phase change that initiates flowering to the final production of fruits and seeds. However, this work has been performed almost exclusively in a small number of eudicot model species, chief among which is Arabidopsis thaliana. Studies of flower development must now be extended to a much wider phylogenetic range of flowering plants and, indeed, to their closest living relatives, the gymnosperms. Studies of further, more wide-ranging models should provide insights that, for various reasons, cannot be obtained by studying the major existing models alone. The use of further models should also help to explain how the first flowering plants evolved from an unknown, although presumably gymnosperm-like ancestor, and rapidly diversified to become the largest major plant group and to dominate the terrestrial flora. The benefits for society of a thorough understanding of flower development are self-evident, as human life depends to a large extent on flowering plants and on the fruits and seeds they produce. In this preface to the Special Issue, we introduce eleven articles on flower development, representing work in both established and further models, including gymnosperms. We also present some of our own views on current trends and future directions of the

  14. [Magnetoreception systems in birds: a review of current research].

    Science.gov (United States)

    Kishkinev, D A; Chernetsov, N S

    2014-01-01

    Currently at least two independent systems of magnetoreception are believed to exist in birds, based on different biophysical principles, located in different parts of their bodies, and having different innervation. One magnetoreceptory system is located in the retina and may be based on photo-induced biradical chemical reactions on the basis of cryptochrome. Information from these receptors is processed in a specialized part of visual Wulst, the so-called Cluster N. There are good reasons to believe that this visual magnetoreceptor processes compass magnetic information which is necessary for migratory orientation. The second magnetoreceptory system is probably iron-based (biogenic magnetite), is located somewhere in the upper beak (its exact location and ultrastructure of receptors remain unknown), and is innervated by the ophthalmic branch of trigeminal nerve. It cannot be ruled out that this system participates in spatial representation and helps forming either a kind of map or more primitive signposts, based on regular spatial variation of the geomagnetic field. The magnetic map probably governs navigation of migrating birds across hundreds and thousands of kilometers. Apart from these two systems whose existence may be considered to be convincingly shown (even if their details are not yet fully clear), there are data on the existence of magnetoreceptors based on the vestibular system. It cannot be ruled out that iron-based magnetoreception takes place in lagena (a structure homologous to cochlea of marsupials and eutherians), and the information perceived is processes in vestibular nuclei. The very existence of this magnetoreception system needs verification, and its function remains completely open.

  15. Nontyphoidal salmonella disease: Current status of vaccine research and development.

    Science.gov (United States)

    Tennant, Sharon M; MacLennan, Calman A; Simon, Raphael; Martin, Laura B; Khan, M Imran

    2016-06-01

    currently under development.

  16. An Investigation on the Current Situation of Management Information Systems Discipline in Turkey

    OpenAIRE

    Serdar YARLIKAŞ

    2015-01-01

    The purpose of this research is to investigate the development of management information systems field by evaluating the theses conducted at universities in Turkey in the departments of management information systems and science of management information systems. First, this study aims to determine the distribution of the theses in terms of years, subjects and the research methods used. Another purpose of this study was to determine which of the related disciplines of management information s...

  17. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research

    Science.gov (United States)

    Minori, Karen

    2017-01-01

    Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice), the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far. PMID:28210503

  18. Microorganisms in metalworking fluids: Current issues in research and management

    Directory of Open Access Journals (Sweden)

    Elżbieta A. Trafny

    2013-02-01

    Full Text Available The microbial contamination of water miscible metalworking fl uids (MWFs is a serious problem in metal industry. A good maintenance of MWF re-circulation systems can extend the lifetime of coolants and ensure the quality of the tools produced. In MWFs, as in the other water-based environments, microorganisms usually live in the form of biofi lms, the communities of bacteria and fungi attached to the surface of sumps, metal parts and also to each other. Biofi lms exhibit very high resistance to biocides. The effect of biocides that are used as additives to MWFs to control the growth of the bacterial and fungal microbiomes (microorganisms characteristic to the individual coolant system have become the subject of research only in recent years. There are also only sparse reports on the impact of biocides on microorganisms growing in biofi lms in MWF installations. Fast growing mycobacteria are important members of these biofi lm communities. Their presence has recently been linked with the occurrence of cases of hypersensitivity pneumonitis, a serious respiratory disorder in the metal industry employees. The new, relatively fast and inexpensive techniques to assess the species diversity within MWF microbiomes and their population size should be developed in order to control the microorganisms’ proliferation in MWFs and to diminish the occupational exposure to harmful bioaerosols in metal industry.

  19. Current practices and research updates on diabetes mellitus in canine

    Directory of Open Access Journals (Sweden)

    Pankaj Kumar

    2014-11-01

    Full Text Available Diabetes has evidence in ancient literatures, though recently is being considered as one amongst the most emerging disease condition in both human and companion animals. Diabetes mellitus is one of the common endocrinopathy of dog characterized by hyperglycemia, glycosuria and weight loss. Reports suggests high fraction of canine population suffer with diabetes world over. Studies in different veterinary hospitals of United States suggest increase in cases of canine diabetes and decrease in case fatality rate over time. Increase in cases of canine diabetes worldwide is attributed to awareness amongst pet owners, better veterinary health facilities, breed preferences by dog owners, increase dependence on commercial feeds, obesity, etc. Diabetes in most dogs is immune mediated and insulin dependent. Breed predisposition in canine is attributed to dog leukocyte antigen gene pool encoding form major histocompatibility complex-II molecules, however research is still underway. Diagnosis of diabetes still relies on blood sugar evaluation for screening of canine population, though many other diagnostic methods have shown promising benefits including measurement of fructosamine and glycated haemoglobin. Management of diabetes in dog is based on insulin therapy, diet modification and exercise. Use of oral anti-diabetics drugs in canine is limited though experimental studies have shown promising results. Alternative therapies have been explored, but only a few approaches have shown promise for clinical application.

  20. Vitamin K metabolism: current knowledge and future research.

    Science.gov (United States)

    Card, David J; Gorska, Renata; Cutler, Jacky; Harrington, Dominic J

    2014-08-01

    Vitamin K is an essential fat-soluble micronutrient that is required for the post-translational γ-carboxylation of specific glutamic acid residues in hepatic and extra-hepatic proteins involved in blood coagulation and preventing cartilage and vasculature calcification. In humans, sources of vitamin K are derived from plants as phylloquinone and bacteria as the menaquinones. Menadione is a synthetic product used as a pharmaceutical but also represents an intermediate in the tissue-specific conversion of vitamin K to menaquinone-4, which preferentially resides in tissues such as brain. Research into vitamin K metabolism is essential for the understanding of vitamin K biology in health and disease. Progress in this area, driven by knowledge of vitamin K and the availability of markers of vitamin K status, has already proved beneficial in many areas of medicine and further opportunities present themselves. Areas of interest discussed in this review include prophylactic administration of vitamin K1 in term and preterm neonates, interactions between vitamins K and E, the industrial conversion of vitamin K to dihydro-vitamin K in foods, tissue-specific conversion of vitamin K to menaquinone-4, the biological activity of the five and seven carbon metabolites of vitamin K and circadian variations.

  1. Current development of acupuncture research in Parkinson's disease.

    Science.gov (United States)

    Zeng, Bai-Yun; Salvage, Sarah; Jenner, Peter

    2013-01-01

    Parkinson's disease is an age-related progressive neurodegenerative disease. The etiology and pathogenetic mechanisms that cause PD are still not fully understood. The available treatments to PD are only symptomatic relief. Acupuncture is used to treat many medical conditions for 1000 years in China and has gained wider and increasing acceptance within both public and medical profession because it has been a very safe and well-tolerated treatment. In this chapter, we reviewed relevant laboratory findings regarding acupuncture mechanism on Parkinson's. We showed that acupuncture stimulation in Parkinson's models had generated valuable mechanistic insight of Parkinson's and showed that acupuncture treatment is in fact a neuroprotective therapy that increase the release of various neuroprotective agents such as brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor, and cyclophilin A. In addition, acupuncture therapy slows cell death process and attenuates oxidative stress to dopaminergic neurons in the substantia nigra. Further, acupuncture therapy modulates neuronal activity of the basal ganglia output structures. These results suggest that early application of acupuncture therapy to Parkinson's patients may be helpful for the best efficacy of acupuncture treatment. It is hopeful that translation of achievement in acupuncture research in Parkinson's models will maximize the potentials of acupuncture treatment.

  2. Current Challenges and Prospective Research for Upscaling Hybrid Perovskite Photovoltaics.

    Science.gov (United States)

    Williams, Spencer T; Rajagopal, Adharsh; Chueh, Chu-Chen; Jen, Alex K-Y

    2016-03-01

    Organic-inorganic hybrid perovskite photovoltaics (PSCs) are poised to push toward technology translation, but significant challenges complicating commercialization remain. Though J-V hysteresis and ecotoxicity are uniquely imposing issues at scale, CH3NH3PbI3 degradation is by far the sharpest limitation to the technology's potential market contribution. Herein, we offer a perspective on the practical market potential of PSCs, the nature of fundamental PSC challenges at scale, and an outline of prospective solutions for achieving module scale PSC production tailored to intrinsic advantages of CH3NH3PbI3. Although integrating PSCs into the energy grid is complicated by CH3NH3PbI3 degradation, the ability of PSCs to contribute to consumer electronics and other niche markets like those organic photovoltaics have sought footing in rests primarily upon the technology's price point. Thus, slot die, roll-to-roll processing has the greatest potential to enable PSC scale-up, and herein, we present a perspective on the research necessary to realize fully printable PSCs at scale.

  3. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research.

    Science.gov (United States)

    Mendes, Tiago; Minori, Karen; Ueta, Marlene; Miguel, Danilo Ciccone; Allegretti, Silmara Marques

    2017-01-01

    Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice), the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far.

  4. Strongyloidiasis Current Status with Emphasis in Diagnosis and Drug Research

    Directory of Open Access Journals (Sweden)

    Tiago Mendes

    2017-01-01

    Full Text Available Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Treatment is also an issue as ivermectin and benzimidazoles administration leads to inconsistent cure rates and several side effects. Researching new anti-Strongyloides drugs is a difficult task since S. stercoralis does not develop until the adult stages in Mus musculus (with the exception of SCID mice, the main experimental host model. Fortunately, alternative parasite models can be used, namely, Strongyloides ratti and S. venezuelensis. However, even with these models, there are other complications in finding new drugs, which are associated with specific in vitro assay protocol steps, such as larvae decontamination. In this review, we highlight the challenges associated with new drug search, the compounds tested, and a list of published in vitro assay methodologies. We also point out advances being made in strongyloidiasis diagnosis so far.

  5. Ovarian aging and menopause: current theories, hypotheses, and research models.

    Science.gov (United States)

    Wu, Julie M; Zelinski, Mary B; Ingram, Donald K; Ottinger, Mary Ann

    2005-12-01

    Aging of the reproductive system has been studied in numerous vertebrate species. Although there are wide variations in reproductive strategies and hormone cycle components, many of the fundamental changes that occur during aging are similar. Evolutionary hypotheses attempt to explain why menopause occurs, whereas cellular hypotheses attempt to explain how it occurs. It is commonly believed that a disruption in the hypothalamic-pituitary-gonadal axis is responsible for the onset of menopause. Data exist to demonstrate that the first signs of menopause occur at the level of the brain or the ovary. Thus, finding an appropriate and representative animal model is especially important for the advancement of menopause research. In primates, there is a gradual decline in the function of the hypothalamic-pituitary-gonadal (HPG) axis ultimately resulting in irregularities in menstrual cycles and increasingly sporadic incidence of ovulation. Rodents also exhibit a progressive deterioration in HPG axis function; however, they also experience a period of constant estrus accompanied by intermittent ovulations, reduced progesterone levels, and elevated circulating estradiol levels. It is remarkable to observe that females of other classes also demonstrate deterioration in HPG axis function and ovarian failure. Comparisons of aging in various taxa provide insight into fundamental biological mechanisms of aging that could underlie reproductive decline.

  6. Asthma in the Elderly: Current Understanding and Future Research Needs

    Science.gov (United States)

    Hanania, Nicola A.; King, Monroe J.; Braman, Sidney S.; Saltoun, Carol; Wise, Robert A.; Enright, Paul; Falsey, Ann A; Mathur, Sameer K.; Ramsdell, Joe W.; Rogers, Linda; Stempel, David A.; Lima, John J.; Fish, James E.; Wilson, Sandra R.; Boyd, Cynthia; Patel, Kushang V.; Irvin, Charles G.; Yawn, Barbara P.; Halm, Ethan A; Wasserman, Stephen I.; Sands, Mark F.; Ershler, William B.; Ledford, Dennis K.

    2011-01-01

    Asthma in the elderly (AIE) is under diagnosed and under treated and there is a paucity of knowledge. The National Institute on Aging convened this workshop to identify what is known, what gaps in knowledge remain and suggest research directions needed to improve the understanding and care of AIE. Asthma presenting at an advanced age often has similar clinical and physiologic consequences as seen with younger individuals but co-morbid illnesses and the psychosocial effects of aging may affect the diagnosis, clinical presentation and care of asthma in this population. At least two phenotypes exist among elderly asthma; those with long-standing asthma have more severe airflow limitation and less complete reversibility than those with late-onset asthma. Many challenges exist in the recognition and treatment of asthma in the elderly. Furthermore, the pathophysiological mechanisms of AIE are likely to be different from those seen in young asthmatics and these differences may influence the clinical course and outcomes of asthma in this population. PMID:21872730

  7. Current progress in epigenetic research for hepato-carcinomagenesis

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Hepatocellular carcinoma is the main type of primary liver cancer,and also one of the most malignant tumors.At present,the pathogenesis mechanisms of liver cancer are not entirely clear.It has been shown that inactivation of tumor suppressor genes and activation of oncogenes play a significant role in carcinogenesis,caused by the genetic and epigenetic aberrance.In the past,people generally thought that genetic mutation is a key event of tumor pathogenesis,and somatic mutation of tumor suppressor genes is in particular closely associated with oncogenesis.With deeper understanding of tumors in recent years,increasing evidence has shown that epigenetic silencing of those genes,as a result of aberrant hypermethylation of CpG islands in promoters and histone modification,is essential to carcinogenesis and metastasis.The term epigenetics refers to heritable changes in gene expression caused by regulation mechanisms,other than changes in the underlying DNA sequence.Specific epigenetic processes include DNA methylation,genome imprinting,chromotin remodeling,histone modification and microRNA regulations.This paper reviews recent epigenetics research progress in the hepatocellular carcinoma study,and tries to depict the relationships between hepatocellular carcinomagenesis and DNA methylation as well as microRNA regulation.

  8. Current progress in epigenetic research for hepato-carcinomagenesis

    Institute of Scientific and Technical Information of China (English)

    HUANG Jian

    2009-01-01

    Hepatocellular carcinoma is the main type of primary liver cancer, and also one of the most malignant tumors. At present, the pathogenesis mechanisms of liver cancer are not entirely clear. It has been shown that inactivation of tumor suppressor genes and activation of oncogenes play a significant role in carcinogenesis, caused by the genetic and epigenetic aberrance. In the past, people generally thought that genetic mutation is a key event of tumor pathogenesis, and somatic mutation of tumor suppressor genes is in particular closely associated with oncogenesis. With deeper understanding of tumors in recent years, increasing evidence has shown that epigenetic silencing of those genes, as a result of aberrant hypermethylation of CpG islands in promoters and histone modification, is essential to carcinogenesis and metastasis. The term epigenetics refers to heritable changes in gene expression caused by regulation mechanisms, other than changes in the underlying DNA sequence. Specific epi-genetic processes include DNA methylation, genome imprinting, chromotin remodeling, histone modi-fication and microRNA regulations. This paper reviews recent epigenetics research progress in the hepatocellular carcinoma study, and tries to depict the relationships between hepatocellular carci-nomagenesis and DNA methylation as well as microRNA regulation.

  9. Henry Mayhew: journalist, social investigator, and foreshadower of qualitative research.

    Science.gov (United States)

    Nunes, Everardo Duarte

    2012-09-01

    As a journalist, Henry Mayhew recorded daily life in London in the latter half of the nineteenth century. His approach remains of interest to historians and social scientists today in that it foreshadowed qualitative research. The article highlights methodological aspects of Mayhew's investigations and analyzes two of his reports, one on a cholera outbreak and the other on a female street vendor. It also addresses some analyses that have critiqued his work.

  10. First language transfer in second language writing: An examination of current research

    Directory of Open Access Journals (Sweden)

    Khaled Karim

    2013-01-01

    Full Text Available First language (L1 transfer has been a key issue in the field of applied linguistics, second language acquisition (SLA, and language pedagogy for almost a century. Its importance, however, has been re-evaluated several times within the last few decades. The aim of this paper is to examine current research that has investigated the role of L1 transfer in second language (L2 writing. The paper begins by discussing the different views of L1 transfer and how they have changed over time and then reviews some of the major studies that have examined the role of L1 transfer both as a learning tool and as a communicative strategy in L2 writing. The paper concludes with a number of suggestions for L2 writing instruction and future research.

  11. Soil Contamination and Remediation Strategies. Current research and future challenge

    Science.gov (United States)

    Petruzzelli, G.

    2012-04-01

    eliminating the source of pollution, but also on blocking the pathways from contaminants to receptors or reducing the exposure to contaminants,. Future challenge integration of sustainability into remediation decision-making. Soil is not a waste! There is a growing interest in the clean up approaches that maintain soil quality after remediation treatments. This issue is of great importance in the U.S.A. where the EPA from 2009 is promoting innovative clean-up strategies (Green Remediation). Green remediation is defined as the practice of considering all environmental effects of remedy and incorporating options to maximize environmental benefit of cleanup actions . These remediation strategies restore contaminated sites to productive use with a great attention to the global environmental quality, including the preservation of soil functionality according to the following principles: use minimally invasive technologies; use passive energy technologies such as bioremediation and phytoremediation as primary remedies or finishing steps where possible and effective; minimize soil and habitat disturbance; minimize bioavailability of contaminants trough adequate contaminant source and plume control If we move from the current definition of remedial targets based on total concentrations, technologies with low impact on the environment can be utilized reducing the wrong choice to disposal soil in landfill destroying quickly a not renewable essential resource.

  12. Radiology Research in Quality and Safety: Current Trends and Future Needs.

    Science.gov (United States)

    Zygmont, Matthew E; Itri, Jason N; Rosenkrantz, Andrew B; Duong, Phuong-Anh T; Mankowski Gettle, Lori; Mendiratta-Lala, Mishal; Scali, Elena P; Winokur, Ronald S; Probyn, Linda; Kung, Justin W; Bakow, Eric; Kadom, Nadja

    2017-03-01

    Promoting quality and safety research is now essential for radiology as reimbursement is increasingly tied to measures of quality, patient safety, efficiency, and appropriateness of imaging. This article provides an overview of key features necessary to promote successful quality improvement efforts in radiology. Emphasis is given to current trends and future opportunities for directing research. Establishing and maintaining a culture of safety is paramount to organizations wishing to improve patient care. The correct culture must be in place to support quality initiatives and create accountability for patient care. Focused educational curricula are necessary to teach quality and safety-related skills and behaviors to trainees, staff members, and physicians. The increasingly complex healthcare landscape requires that organizations build effective data infrastructures to support quality and safety research. Incident reporting systems designed specifically for medical imaging will benefit quality improvement initiatives by identifying and learning from system errors, enhancing knowledge about safety, and creating safer systems through the implementation of standardized practices and standards. Finally, validated performance measures must be developed to accurately reflect the value of the care we provide for our patients and referring providers. Common metrics used in radiology are reviewed with focus on current and future opportunities for investigation. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  13. Effects of micro- and nanoplastics on aquatic ecosystems: Current research trends and perspectives.

    Science.gov (United States)

    Chae, Yooeun; An, Youn-Joo

    2017-02-17

    Contamination by bulk plastics and plastic debris is currently the one of the most serious environmental problems in aquatic ecosystems. In particular, small-scale plastic debris such as microplastics and nanoplastics has become leading contributors to the pollution of marine and freshwater ecosystems. Studies are investigating the impacts of micro-and nanoplastics on aquatic organisms and ecosystems worldwide. This review covers 83 studies that investigated the distribution of microplastics and the ecotoxicity of micro- and nanoplastics in marine and freshwater ecosystems. The studies indicated that micro-sized plastics and plastic debris were distributed at various concentrations in aquatic ecosystems around the world. They had various effects on the growth, development, behavior, reproduction, and mortality of aquatic animals. We discuss these studies in detail and suggest directions for future research.

  14. Simulation and investigation of SiPM’s leakage currents at low voltages

    Science.gov (United States)

    Parygin, P. P.; Popova, E. V.; Grachev, V. M.

    2017-01-01

    Technology Computer-Aided Design (TCAD) allows us to use computers in order to develop semiconductor processing technologies and devices and optimize them. Within a framework of a study of silicon photomultipliers (SiPM) a simulation of these devices has been made. The simulation was performed for the irradiated SiPMs and current-voltage characteristics were obtained for the modeled devices. Investigation of current-voltage curve below breakdown with regard to the simulated structure was performed. Obtained curves are presented.

  15. The Current State of Research on Networks in China’s Business System

    NARCIS (Netherlands)

    J. Meuer (Johannes); B. Krug (Barbara)

    2009-01-01

    textabstractThe purpose of the paper is to assess the current state of network research in China’s business system. Research on networks has developed significantly during the last decades in regards to analytic techniques, number of research projects, and accumulated findings. While research on net

  16. The Current State of Research on Networks in China’s Business System

    NARCIS (Netherlands)

    J. Meuer (Johannes); B. Krug (Barbara)

    2009-01-01

    textabstractThe purpose of the paper is to assess the current state of network research in China’s business system. Research on networks has developed significantly during the last decades in regards to analytic techniques, number of research projects, and accumulated findings. While research on net

  17. Current research and future directions in pattern identification: Results of an international symposium.

    Science.gov (United States)

    Lee, Myeong Soo; Lee, Ju Ah; Alraek, Terje; Bian, Zhao-Xiang; Birch, Stephen; Goto, Hirozo; Jung, Jeeyoun; Kao, Shung-Te; Moon, Sang-Kwan; Park, Bongki; Park, Kyung-Mo; You, Sooseong; Yun, Kyung-Jin; Zaslawski, Chris

    2016-12-01

    A symposium on pattern identification (PI) was held at the Korea Institute of Oriental Medicine (KIOM) on October 2, 2013, in Daejeon, South Korea. This symposium was convened to provide information on the current research in PI as well as suggest future research directions. The participants discussed the nature of PI, possible research questions, strategies and future international collaborations in pattern research. With eight presentations and an extensive panel discussion, the symposium allowed participants to discuss research methods in traditional medicine for PI. One speaker presented the topic, 'Clinical pattern differentiation and contemporary research in PI.' Two speakers presented current trends in research on blood stasis while the remaining five other delegates discussed the research methods and future directions of PI research. The participants engaged in in-depth discussions regarding the nature of PI, potential research questions, strategies and future international collaborations in pattern research.

  18. Principle and experimental investigation of current-driven negative-inductance superconducting quantum interference device

    Science.gov (United States)

    Li, Hao; Liu, Jianshe; Zhang, Yingshan; Cai, Han; Li, Gang; Liu, Qichun; Han, Siyuan; Chen, Wei

    2017-03-01

    A negative-inductance superconducting quantum interference device (nSQUID) is an adiabatic superconducting logic device with high energy efficiency, and therefore a promising building block for large-scale low-power superconducting computing. However, the principle of the nSQUID is not that straightforward and an nSQUID driven by voltage is vulnerable to common mode noise. We investigate a single nSQUID driven by current instead of voltage, and clarify the principle of the adiabatic transition of the current-driven nSQUID between different states. The basic logic operations of the current-driven nSQUID with proper parameters are simulated by WRspice. The corresponding circuit is fabricated with a 100 A cm‑2 Nb-based lift-off process, and the experimental results at low temperature confirm the basic logic operations as a gated buffer.

  19. The Investigation of Primary School Teachers' Opinions Related to the Current Events

    Directory of Open Access Journals (Sweden)

    Halil İbrahim Sağlam

    2016-09-01

    Full Text Available The aim of this study is to examine primary school teachers’ opinions related to current events. The study group is consisted of total 30 primary school teachers who take part in THE GROUPS OF 15 female (%50 and 15 male (%50 in Sakarya during 2015 -2016 the education year. The study is carried out under science facts pattern of qualitative research designs. In order to reveal teachers’ views on current events, the form of semi-structured interviews from which is qualitative data collection tools is used. There are two sections in this study. First section is about teachers' personal information and second section is about teachers' questions to determine their views on current events. For the content validity of the questions in the negotiation form, it has been consulted with three experts and made the necessary adjustments in line with their proposals. In addition, the clarity of the questions in the negotiation form has been checked by discussing with five teachers and then the form has been finalized. The data obtained from teachers ARE analyzed by using content analysis. In the study, it is concluded that 97% of the teachers follow the current events. It is shown that 93% of female teachers and 100% male teachers follow the current events. FURTHERMORE, it is indicated that %100 of the teachers use the internet in their house.

  20. Payment of research participants: current practice and policies of Irish research ethics committees.

    LENUS (Irish Health Repository)

    Roche, Eric

    2013-09-01

    Payment of research participants helps to increase recruitment for research studies, but can pose ethical dilemmas. Research ethics committees (RECs) have a centrally important role in guiding this practice, but standardisation of the ethical approval process in Ireland is lacking.

  1. Wave-current interactions at the FloWave Ocean Energy Research Facility

    Science.gov (United States)

    Noble, Donald; Davey, Thomas; Steynor, Jeffrey; Bruce, Tom; Smith, Helen; Kaklis, Panagiotis

    2015-04-01

    Physical scale model testing is an important part of the marine renewable energy development process, allowing the study of forces and device behaviour in a controlled environment prior to deployment at sea. FloWave is a new state-of-the-art ocean energy research facility, designed to provide large scale physical modelling services to the tidal and wave sector. It has the unique ability to provide complex multi-directional waves that can be combined with currents from any direction in the 25m diameter circular tank. The facility is optimised for waves around 2s period and 0.4m height, and is capable of generating currents upwards of 1.6m/s. This offers the ability to model metocean conditions suitable for most renewable energy devices at a typical scale of between 1:10 and 1:40. The test section is 2m deep, which can be classed as intermediate-depth for most waves of interest, thus the full dispersion equation must be solved as the asymptotic simplifications do not apply. The interaction between waves and currents has been studied in the tank. This has involved producing in the tank sets of regular waves, focussed wave groups, and random sea spectra including multi-directional sea states. These waves have been both inline-with and opposing the current, as well as investigating waves at arbitrary angles to the current. Changes in wave height and wavelength have been measured, and compared with theoretical results. Using theoretical wave-current interaction models, methods have been explored to "correct" the wave height in the central test area of the tank when combined with a steady current. This allows the wave height with current to be set equal to that without a current. Thus permitting, for example, direct comparison of device motion response between tests with and without current. Alternatively, this would also permit a specific wave height and current combination to be produced in the tank, reproducing recorded conditions at a particular site of interest. The

  2. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  3. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  4. A Sustainable Model for Integrating Current Topics in Machine Learning Research into the Undergraduate Curriculum

    Science.gov (United States)

    Georgiopoulos, M.; DeMara, R. F.; Gonzalez, A. J.; Wu, A. S.; Mollaghasemi, M.; Gelenbe, E.; Kysilka, M.; Secretan, J.; Sharma, C. A.; Alnsour, A. J.

    2009-01-01

    This paper presents an integrated research and teaching model that has resulted from an NSF-funded effort to introduce results of current Machine Learning research into the engineering and computer science curriculum at the University of Central Florida (UCF). While in-depth exposure to current topics in Machine Learning has traditionally occurred…

  5. A Sustainable Model for Integrating Current Topics in Machine Learning Research into the Undergraduate Curriculum

    Science.gov (United States)

    Georgiopoulos, M.; DeMara, R. F.; Gonzalez, A. J.; Wu, A. S.; Mollaghasemi, M.; Gelenbe, E.; Kysilka, M.; Secretan, J.; Sharma, C. A.; Alnsour, A. J.

    2009-01-01

    This paper presents an integrated research and teaching model that has resulted from an NSF-funded effort to introduce results of current Machine Learning research into the engineering and computer science curriculum at the University of Central Florida (UCF). While in-depth exposure to current topics in Machine Learning has traditionally occurred…

  6. The Research of College Students’English Classroom Behavior Investigations

    Institute of Scientific and Technical Information of China (English)

    张单

    2014-01-01

    By employing quantitative research methods, the paper investigates college students ’preferences to English classroom behaviors and the relations between behaviors and achievements. The results indicate that there are significant differences among the subjects’behavior, cognitive and emotional elements, and their classroom behaviors are mainly visual, individual, imitative and exterior-motivated;there are significant differences in behavior element and emotional element between high-result group and low-result group;confident and oral classroom behaviors have prominent relations with CET-4 achievements, and different teaching methods may make learning behaviors produce good or bad effects to achievements.

  7. Corrosion investigations, Tracy Red Bluff, California, and Boulder City, Nevada, ehv direct current tests

    Energy Technology Data Exchange (ETDEWEB)

    Backstrom, T.E.

    1965-01-01

    Evaluation of corrosion on buried metalwork, by the introduction of large direct currents into the ground, was studied during ehv dc transmission investigations in the Tracy-Red Bluff, California and the Boulder City, Nevada areas. Tests made on two types of electrodes showed that ehv dc ground return at test current levels would: (1) promote serious corrosion of buried metalwork within approximately 1/2-mile radius of the electrode with a ground mat electrode and mild corrosion with a deep-well electrode; (2) promote negligible-to-serious corrosion of buried pipelines within 1/2 to 3 mile radius of either a ground mat or deep-well electrode, depending on (a) distance of the pipelines from the electrode, (b) geometry of the two electrode-pipeline systems, and (c) horizontal extent of the pipelines; (3) impress negligible-to-mild corrosion of buried pipelines beyond a 3-mile radius of the electrode depending upon geometry of the electrode-pipeline system. Results show normal corrosion prevention techniques will be adequate to prevent corrosion of buried metalwork, if electrode is properly located. Use of ground return for only 8 to 24 hours per year on the ehv intertie, although with currents 2 to 3 times higher than test currents, will cause stray current damage of only a fraction of that expected with continuous operations.

  8. Current Research.

    Science.gov (United States)

    Hunt, Mary Alice

    1981-01-01

    Describes a doctoral dissertation entitled "World-Future Images in Childrens Literature" which analyzed books on science fiction or utopian fiction by 43 authors of children's literature to determine whether presentations were optimistic or pessimistic. Results indicating generally optimistic stories are discussed, as well as strengths and…

  9. Investigating minority student participation in an authentic science research experience

    Science.gov (United States)

    Preston, Stephanie Danette

    In the United States, a problem previously overlooked in increasing the total number of scientifically literate citizens is the lack of diversity in advanced science classes and in science, technology, engineering, and mathematics (STEM) fields. Groups traditionally underserved in science education and thus underrepresented in the STEM fields include: low-income, racial/ethnic minorities, and females of all ethnic and racial backgrounds. Despite the number of these students who are initially interested in science very few of them thrive in the discipline. Some scholars suggest that the declining interest for students underrepresented in science is traceable to K-12th grade learning experiences and access to participating in authentic science. Consequently, the diminishing interest of minorities and women in science contributes negatively to the representation of these groups in the STEM disciplines. The purpose of this study was to investigate a summer science research experience for minority students and the nature of students' participation in scientific discourse and practices within the context of the research experience. The research questions that guided this study are: The nature of the Summer Experience in Earth and Mineral Science (SEEMS) research experience . (A) What are the SEEMS intended outcomes? (B) To what extent does SEEMS enacted curriculum align with the intended outcomes of the program? The nature of students engagement in the SEEMS research. (A) In what ways do students make sense of and apply science concepts as they engage in the research (e.g., understand problem, how they interpret data, how they construct explanations), and the extent to which they use the science content appropriately? (B) In what ways do students engage in the cultural practices of science, such as using scientific discourse, interpreting inscriptions, and constructing explanations from evidence (engaging in science practices, knowing science and doing science)? The

  10. Laboratory Investigations of Current Sheets at the Electron Skin Depth Scale

    Science.gov (United States)

    Vincena, S.; Gekelman, W.

    2005-12-01

    Laboratory Investigations of Current Sheets at the Electron Skin Depth Scale. Theoretical investigations, in situ spacecraft and rocket missions, and laboratory studies form an essential triad for understanding the variety of current sheet phenomena found in space plasmas. In the Large Plasma Device (LAPD) at UCLA, the formation dynamics, equilibrium state, and wave-mediated disruptions of current sheets can be studied with great spatial and temporal resolution using a variety of probes as well as non-invasive laser induced fluorescence and other optical diagnostics. The LAPD is aptly suited for studying current sheets flowing in a magnetized background plasma which is capable of supporting Alfvén waves. The cylindrical device is 20m long and one meter in diameter with a solenoidal magnetic field as high as 3000 Gauss. For the parameters in this experiment, the plasma column is ten shear Alfvén wavelengths along the field and 100 electron inertial lengths (δe) (or 200 ρi) in the perpendicular direction. An electron current sheet is created in the plasma by placing a thin copper plate in the plasma column at one end of the device and pulsing this plate positive with respect to the chamber wall. The current sheet extends for the length of the device and has an initial cross-field size of roughly 45 δe by 0.5δe. A parallel flow of ions is observed with similar dimensions and moves in the same direction as the electrons in the current sheet with a velocity of 0.2 times the ion sound speed. A much weaker sheared perpendicular flow is also measured. Cross-sections of the ion flow are measured at several axial locations over a distance of six meters. Second, as the ion flow increases in magnitude, a much broader (8ρi) density depletion (n=0.25nO) develops around the flow. The gradient scale length of the depletion shortens until the spontaneous growth of drift waves occurs. This disrupts the electron current and ion flow, and leads to cross-field transport of

  11. Investigating Current Status of English for Academic Purposes (EAP in Iran; Revisiting ESP Specificity Continuum

    Directory of Open Access Journals (Sweden)

    Marjan Vosoughi

    2013-05-01

    Full Text Available The EAP textbooks which are currently taught in Iranian universities don't seem to satisfy the necessary requirements current in new enquires of EAP research.  An EAP book sample from SAMT 1 publications for the students of medicine was chosen for a critical analysis on three criteria including: evaluating the objectives, reviewing the content, and evaluating the overall structure. The exploratory reviews showed that there must be major changes in EAP for medical students of SAMT to meet the specific needs of the target group above. In this article, the general status of ESP material development approaches is also depicted diachronically in order to evaluate the present situation in Iran against appropriate recent approaches towards EAP material development in the world. Recommended implications of some kind are presented throughout the various parts of the present survey.     Keywords: EAP materials, English for medical purposes (EMP, specificity continuum, material development

  12. Investigations on bipolar radio-frequency current application for interstitial thermotherapy (RF-ITT)

    Science.gov (United States)

    Desinger, Kai; Mueller, Gerhard J.; Stein, Thomas; Tschepe, Johannes

    1996-01-01

    This paper discusses the feasibility of radio-frequency current in bipolar technique for interstitial thermotherapy (rf-ITT). A short survey of established methods for interstitial tissue coagulation, e.g. the interstitial laser photocoagulation (ILP) and microwave exposure are given. In addition, a new concept for interstitial application of bipolar or quasi-bipolar radio- frequency alternating current is presented. Theoretical investigations of the electrical field distribution generated by a dipole model come together in the different mechanisms of heat generation by using radio-frequency alternating current. New concepts of bipolar or quasi- bipolar coaxial layered applicators are presented. This bipolar needle electrode enables the surgeon to use a partial and homogeneous exposure of radio-frequency current for interstitial thermotherapy, e.g. for the treatment of BPH or for concha coagulation in ENT. Less power is needed due to the limited current exposition at the immediate operation site and a highly safe procedure is possible. Therefore, to determine the thermal damage of tissue, depending on the rf parameters, a computer model for a real-time simulation of the spatial electrical field distribution especially for a multiple probe application is currently being developed. This is an appropriate tool for dosimetry. A similar program for LITT, called LITCIT, developed at the Laser-Medizin-Zentrum Berlin has already shown its efficiency in clinical use. Furthermore the feasibility of a 'cross-over' applicator is discussed which combines ILP and rf-application by using metallized optical fibers for a simultaneous application of electrical energy and laser radiation.

  13. Research of Current Issues and Preliminary Sensitivity Analysis of Level 3 PSA

    Energy Technology Data Exchange (ETDEWEB)

    Shin, So Eun; Lee, Yong Suk [FNC Technology Co. Ltd., Yongin (Korea, Republic of); Lee, Seung Woo [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    Thus, in this study, key current issues came from research on previous studies related to L3 PSA. L3 PSA has been carried out by using MACCS code in Korea on a trial basis. The technique of assessing an off-site radiation effect quantitatively is required because the interest in off-site consequence analysis has been increased after the Fukushima accident. Therefore, in order to use Level 3 PSA(L3 PSA) in Korea, methods of calculating MACCS(MELCOR Accident Consequence Code System) code to be adequate for domestic circumstances in Korea were investigated. If L3 PSA is performed in Korea, it will be possible to raise many issues. Since MACCS code is based on the U.S., input parameters and the scope of analysis were set by considering circumstances of the U.S. For this reason, by focusing on solutions to current issues, the method for reflecting circumstances of Korea in L3 PSA was investigated. It is also required to find out methods for decreasing uncertainty of L3 PSA in Korea.

  14. Current Practice in Measuring the Quality of Conceptual Models:Challenges and Research%Current Practice in Measuring the Quality of Conceptual Models:Challenges and Research

    Institute of Scientific and Technical Information of China (English)

    LIU Lei; WU Yu-feng; LI Xiao-jun

    2012-01-01

    How to measure the quality of conceptual models is an important issue in the IS field and related research. This paper conducts a review of research in measuring conceptual model quality and identifies the major theoretical and practical issues that need to be addressed in future studies. We review current classification frameworks for conceptual model quality and practice of measuring conceptual model quality. Based on the review, challenges for studies of measuring the quality of conceptual models are proposed and these challenges are also research points which should be strengthened in future studies.

  15. Navigation Hydraulics Research Program: Evaluation of Nanjing Hydraulic Research Institute Physical Model Current Meter.

    Science.gov (United States)

    1990-07-01

    readout circuit CURRENT VELOCITY / DIRECTION SENSOR A mini-servomotor and a piece of fibre optic rod are installed at the base. The rod is turned by...34Description. of The Fibre - Optic Type Miniature Propetler Velocity Meter" for detal Is) THE OPERATION OF THE COMBINED CURRENT VELOCITY ’ DIRECTION METER 1. Plug...of The Fibre - Optic Type Miniature propeller Velocity Meter" for details. Front Panel: Ma /jj (tPj ) Current Direction Readout (Degree) Sensitivity

  16. Investigation of scaling properties of a thin current sheet by means of particle trajectories study

    CERN Document Server

    Sasunov, Yu L; Alexeev, I I; Belenkaya, E S; Semenov, V S; Kubyshkin, I V; Mingalev, O V

    2015-01-01

    A thin current sheet (TCS), with the width of an order of thermal proton gyroradius, appears a fundamental physical object which plays an important role in structuring of major magnetospheric current systems (magnetotail, magnetodisk, etc.). The TCSs are nowadays under extensive study by means of space missions and theoretical models. We consider a simple model of the TCS separating two half-spaces occupied by a homogenous magnetic field of opposite sign tangential to the TCS; a small normal component of the magnetic field is prescribed. An analytical solution for the electric current and plasma density in the close vicinity of the TCS has been obtained and compared with numerical simulation. The number density and the electric current profiles have two maxima each. The characteristic spatial scale $z_S$ of the maxima location was investigated as a function of initial pitch-angle of an incoming charge particle. The effect of the thermal dispersion of the incoming proton beam have been taken into consideration...

  17. Experimental Investigations on PV Powered SVM-DTC Induction Motor without AC Phase Current Sensors

    Directory of Open Access Journals (Sweden)

    T. Muthamizhan

    2014-05-01

    Full Text Available The paper presents a low-cost, phase-current reconstruction algorithm for space vector modulated direct torque controlled induction motor using the information obtained from only one shunt resistor which is in series with low side switches in a conventional three-phase inverter. The aim is to develop a low-cost high - performance induction motor drive. It uses the dc-link voltage and dc current to reconstruct the stator currents needed to estimate the motor flux and the electromagnetic torque. Photovoltaic arrays convert solar power to dc electric power; uses chopper and dc-ac inverter to fed three phase Induction Motor. The chopper used here is current fed full bridge boost dc-dc converter, which is preferred and extensively used in high voltage applications and advantageous over voltage fed converters. The inverter switches are controlled by PWM techniques obtained from SVM-DTC of IM. The experimental investigations are given to prove the ability of the proposed scheme of reproducing the performances of a SVM- DTC IM drive.

  18. Investigation of helium ion production in constricted direct current plasma ion source with layered-glows

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yuna [Department of Nuclear Engineering, Seoul National University, Seoul 151-744 (Korea, Republic of); Chung, Kyoung-Jae, E-mail: jkjlsh1@snu.ac.kr [Center for Advance Research in Fusion Reactor Engineering, Seoul National University, Seoul 151-744 (Korea, Republic of); Park, Yeong-Shin [Samsumg Electronics Co. Ltd., Gyeonggi 445-701 (Korea, Republic of); Hwang, Y. S. [Department of Nuclear Engineering, Seoul National University, Seoul 151-744 (Korea, Republic of); Center for Advance Research in Fusion Reactor Engineering, Seoul National University, Seoul 151-744 (Korea, Republic of)

    2014-02-15

    Generation of helium ions is experimentally investigated with a constricted direct current (DC) plasma ion source operated at layered-glow mode, in which electrons could be accelerated through multiple potential structures so as to generate helium ions including He{sup 2+} by successive ionization collisions in front of an extraction aperture. The helium discharge is sustained with the formation of a couple of stable layers and the plasma ball with high density is created near the extraction aperture at the operational pressure down to 0.6 Torr with concave cathodes. The ion beam current extracted with an extraction voltage of 5 kV is observed to be proportional to the discharge current and inversely proportional to the operating pressure, showing high current density of 130 mA/cm{sup 2} and power density of 0.52 mA/cm{sup 2}/W. He{sup 2+} ions, which were predicted to be able to exist due to multiple-layer potential structure, are not observed. Simple calculation on production of He{sup 2+} ions inside the plasma ball reveals that reduced operating pressure and increased cathode area will help to generate He{sup 2+} ions with the layered-glow DC discharge.

  19. Global competencies of regional stem cell research: bibliometrics for investigating and forecasting research trends.

    Science.gov (United States)

    Watatani, Kenji; Xie, Zhongquan; Nakatsuji, Norio; Sengoku, Shintaro

    2013-09-01

    We employed a bibliometric approach to examine regional stem cell research in the USA, the UK, Japan and China based on publications from 2007 to 2011 with a co-citation clustering analysis to identify region-specific clusters of global competencies. We observed that there are clear differences in the number and interdisciplinary spread of competencies across regions: the USA retains the largest capacity and capability for pursuing medical and pharmaceutical applications; China has shown substantial growth through fusion approaches with chemistry and material sciences; Japan has been pursuing basic biology and is currently seeking further growth; and the UK has shown considerable growth and quality with a focus on medical research and the widest interdisciplinary spread. Furthermore, we discuss policy implications from these results in terms of industrial and clinical applications. These findings provide a rational way of evaluating research policies and forecasting research trends.

  20. Investigation of assumptions underlying current safety guidelines on EM-induced nerve stimulation

    Science.gov (United States)

    Neufeld, Esra; Vogiatzis Oikonomidis, Ioannis; Iacono, Maria Ida; Angelone, Leonardo M.; Kainz, Wolfgang; Kuster, Niels

    2016-06-01

    An intricate network of a variety of nerves is embedded within the complex anatomy of the human body. Although nerves are shielded from unwanted excitation, they can still be stimulated by external electromagnetic sources that induce strongly non-uniform field distributions. Current exposure safety standards designed to limit unwanted nerve stimulation are based on a series of explicit and implicit assumptions and simplifications. This paper demonstrates the applicability of functionalized anatomical phantoms with integrated coupled electromagnetic and neuronal dynamics solvers for investigating the impact of magnetic resonance exposure on nerve excitation within the full complexity of the human anatomy. The impact of neuronal dynamics models, temperature and local hot-spots, nerve trajectory and potential smoothing, anatomical inhomogeneity, and pulse duration on nerve stimulation was evaluated. As a result, multiple assumptions underlying current safety standards are questioned. It is demonstrated that coupled EM-neuronal dynamics modeling involving realistic anatomies is valuable to establish conservative safety criteria.

  1. An Official American Thoracic Society Research Statement: Current Understanding and Future Research Needs in Tobacco Control and Treatment.

    Science.gov (United States)

    Leone, Frank T; Carlsen, Kai-Hakon; Folan, Patricia; Latzka, Karen; Munzer, Alfred; Neptune, Enid; Pakhale, Smita; Sachs, David P L; Samet, Jonathan; Upson, Dona; White, Alexander

    2015-08-01

    Since the mid-20th century, the scientific community has substantially improved its understanding of the worldwide tobacco epidemic. Although significant progress has been made, the sheer enormity and scope of the global problem put it on track to take a billion lives this century. Curbing the epidemic will require maximizing the impact of proven tools as well as the development of new, breakthrough methods to help interrupt the spread of nicotine addiction and reduce the downstream morbidity. Members of the Tobacco Action Committee of the American Thoracic Society queried bibliographic databases, including Medline, Embase, and the Cochrane Collaborative, to identify primary sources and reviews relevant to the epidemic. Exploded search terms were used to identify evidence, including tobacco, addiction, smoking, cigarettes, nicotine, and smoking cessation. Evidence was consolidated into three thematic areas: (1) determinants of risk, (2) maternal-fetal exposure, and (3) current tobacco users. Expert panel consensus regarding current gaps in understanding and recommendations for future research priorities was generated through iterative discussion. Although much has been accomplished, significant gaps in understanding remain. Implementation often lags well behind insight. This report identifies a number of investigative opportunities for significantly reducing the toll of tobacco use, including: (1) the need for novel, nonlinear models of population-based disease control; (2) refinement of "real-world" models of clinical intervention in trial design; and (3) understanding of mechanisms by which intrauterine smoke exposure may lead to persistent, tobacco-related chronic disease. In the coming era of tobacco research, pooled talent from multiple disciplines will be required to further illuminate the complex social, environmental and biological codeterminants of tobacco dependence.

  2. To investigate or not to investigate? Researchers' views on unexplored atmospheric light phenomena

    Science.gov (United States)

    Caron, Etienne; Faridi, Pouya

    2016-02-01

    For hundreds of years, scientists have been studying light, which is used nowadays to explore the universe and cure diseases. Here, we present the results of a survey indicating a significant support from a subset of the academic community to investigate rare, unusual and unexplained atmospheric light phenomena that have historically been unexplored by scientists — the transient luminous phenomena in the valley of Hessdalen in Norway in particular. We propose that stable, long-term funding, and thorough investigation of poorly understood and/or unexplored luminous phenomena occurring in the low atmosphere could lead to the creation of new inter-disciplinary research programs in multiple universities, and ultimately, to important fundamental discoveries in the field of atmospheric science, photonics and beyond.

  3. EXPERIMENTAL INVESTIGATIONS ON DIFFUSION CHARACTERISTICS OF HIGH CONCENTRATION JETS IN ENVIRONMENTAL CURRENTS

    Institute of Scientific and Technical Information of China (English)

    张燕; 王道增; 樊靖郁

    2002-01-01

    By means of flow visualization and quantitative measurement, the diffusionpattern and concentration distribution characteristics of high concentration jets verticallydischarged into shallow moving waterbody were experimentally investigated in waterchannel. The interactions between the high concentration jets and environmental flowconditions were analysed, and the formulae of impinging point coordinate and transversespread angle are gained from data analysis. Experimental results indicate that the jets showcomplicated flow patterns and diffusion characteristics in near region, which are differentfrom common submerged jets, and spread downstream in the manner of density currents.

  4. An investigation into the lepton flavor changing neutral current at a Z-factory

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The potential for detecting the lepton flavor changing neutral current (LFCNC) via the Z → eτ rare decay at a Z-factory is investigated.Practicable event selection strategies are designed to increase signal significance over SM contributions.Assuming no apparent deviation from SM predictions,one can conclude that the most general model-independent LFCNC effective form factors would be constrained at an unprecedent level,and accordingly a 3-order improvement from LEP1 measurements on the upper limit of BR(Z → eτ) could be achieved,as precisely as 10-8 with 100 fb-1 at Z-factory.

  5. Chosen Aspects Of Investigations Of Solar Cells With The Laser Beam Induced Current Technique

    Directory of Open Access Journals (Sweden)

    Chrobak Łukasz Bartłomiej

    2015-06-01

    Full Text Available This paper presents maps of spatial distributions of the short circuit current Isc(x,y and the open circuit voltage Uoc(x,y of the investigated low cost solar cells. Visible differences in values of these parameters were explained by differences in the serial and shunt resistances determined for different points of solar cells from measurements of I–V characteristics. The spectral dependence of the photo voltage of solar cell is also shown, discussed and interpreted in the model of amorphous and crystal silicon.

  6. Beam brilliance investigation of high current ion beams at GSI heavy ion accelerator facility

    Energy Technology Data Exchange (ETDEWEB)

    Adonin, A. A., E-mail: a.adonin@gsi.de; Hollinger, R. [Linac and Operations/Ion Sources, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany)

    2014-02-15

    In this work the emittance measurements of high current Ta-beam provided by VARIS (Vacuum Arc Ion Source) ion source are presented. Beam brilliance as a function of beam aperture at various extraction conditions is investigated. Influence of electrostatic ion beam compression in post acceleration gap on the beam quality is discussed. Use of different extraction systems (single aperture, 7 holes, and 13 holes) in order to achieve more peaked beam core is considered. The possible ways to increase the beam brilliance are discussed.

  7. An Overview of Current Capabilities and Research Activities in the Airspace Operations Laboratory at NASA Ames Research Center

    Science.gov (United States)

    Prevot, Thomas; Smith, Nancy M.; Palmer, Everett; Callantine, Todd; Lee, Paul; Mercer, Joey; Homola, Jeff; Martin, Lynne; Brasil, Connie; Cabrall, Christopher

    2014-01-01

    The Airspace Operations Laboratory at NASA Ames conducts research to provide a better understanding of roles, responsibilities, and requirements for human operators and automation in future air traffic management (ATM) systems. The research encompasses developing, evaluating, and integrating operational concepts and technologies for near-, mid-, and far-term air traffic operations. Current research threads include efficient arrival operations, function allocation in separation assurance and efficient airspace and trajectory management. The AOL has developed powerful air traffic simulation capabilities, most notably the Multi Aircraft Control System (MACS) that is used for many air traffic control simulations at NASA and its partners in government, academia and industry. Several additional NASA technologies have been integrated with the AOL's primary simulation capabilities where appropriate. Using this environment, large and small-scale system-level evaluations can be conducted to help make near-term improvements and transition NASA technologies to the FAA, such as the technologies developed under NASA's Air Traffic Management Demonstration-1 (ATD-1). The AOL's rapid prototyping and flexible simulation capabilities have proven a highly effective environment to progress the initiation of trajectory-based operations and support the mid-term implementation of NextGen. Fundamental questions about accuracy requirements have been investigated as well as realworld problems on how to improve operations in some of the most complex airspaces in the US. This includes using advanced trajectory-based operations and prototype tools for coordinating arrivals to converging runways at Newark airport and coordinating departures and arrivals in the San Francisco and the New York metro areas. Looking beyond NextGen, the AOL has started exploring hybrid human/automation control strategies as well as highly autonomous operations in the air traffic control domain. Initial results

  8. Sounding Rocket Experiments to Investigate Thermal Electron Heating in the Sq Current Focus

    Science.gov (United States)

    Abe, T.; Ishisaka, K.; Kumamoto, A.; Yoshikawa, A.; Takahashi, T.; Tanaka, M.

    2015-12-01

    Sounding rocket observations in the southern part of Japan suggest that the electron temperature profile occasionally exhibits the local increase by several hundred K at 100-110 km altitudes at 1100-1200 LT in winter. Detailed study of the temperature profiles indicates that such an increase is closely related to the existence of Sq current focus, because it becomes more significant when the measurement is made near the center of Sq focus. In order to understand a general feature of this unusual phenomena occurring in the Sq current focus, the sounding rocket experiment was conducted in Uchinoura of Japan. In this experiment, we launched "S-310-37" rocket equipped with a total of eight science instruments at 11:20 JST on January 16, 2007 after being convinced that the Sq current was approaching to the planned rocket trajectory. The geomagnetic activity had been successively quiet on that day so that we can estimate the position of Sq current focus. Our analysis of the obtained data indicates that the electron temperature was certainly increased by about 500-600 K at the altitude of 97-101 km with respect to the background. Strong electron density perturbation was also observed to exist above 97 km altitude, which corresponds to the lower boundary of the high electron temperatures. It is also noticeable that both the electric field and magnetic field data include unusual variation in the same altitude region as the temperature increase was observed, suggesting a possible connection between the thermal electron heating and variation of the electric and/or magnetic field. Thus, the first experiment in 2007 revealed a general feature of such unusual phenomena in the Sq current focus, and thereby our interest to the generation mechanism for increasing the electron temperature was more and more increased. We will conduct the second rocket experiment to investigate such unusual phenomena in the Sq current focus in January 2016. In this experiment, we will try to measure

  9. Investigation of the characteristics of GIDL current in 90nm CMOS technology

    Institute of Scientific and Technical Information of China (English)

    Chen Hai-Feng; Hao Yue; Ma Xiao-Hua; Zhang Jin-Cheng; Li Kang; Cao Yan-Rong; Zhang Jin-Feng; Zhou Peng-Ju

    2006-01-01

    A specially designed experiment is performed for investigating gate-induced drain leakage (GIDL) current in 90nm CMOS technology using lightly-doped drain (LDD) NMOSFET. This paper shows that the drain bias VD has a strong effect on GIDL current as compared with the gate bias VG at the same drain-gate voltage VDG-It is found that the difference between ID in the off-state ID-VG characteristics and the corresponding one in the off-state ID-VD characteristics, which is defined as /DIFF, versus VDG shows a peak. The difference between the influences of VD and VG on GIDL current is shown quantitatively by /DIFF, especially in 90nm scale. The difference is due to different hole tunnellings. Furthermore, the maximum /DIFF(IDIFF.MAX) varies linearly with VDG in logarithmic coordinates and also VDG at IDIFF.MAX with VF which is the characteristic voltage of /DIFF- The relations are studied and some related expressions are given.

  10. Investigating Effects of Nano- to Micro-Ampere Alternating Current Stimulation on Trichophyton rubrum Growth

    Science.gov (United States)

    Kwon, Dong Rak; Kwon, Hyunjung; Lee, Woo Ram

    2016-01-01

    Background Fungi are eukaryotic microorganisms including yeast and molds. Many studies have focused on modifying bacterial growth, but few on fungal growth. Microcurrent electricity may stimulate fungal growth. Objective This study aims to investigate effects of microcurrent electric stimulation on Trichophyton rubrum growth. Methods Standard-sized inoculums of T. rubrum derived from a spore suspension were applied to potato dextrose cornmeal agar (PDACC) plates, gently withdrawn with a sterile pipette, and were applied to twelve PDACC plates with a sterile spreader. Twelve Petri dishes were divided into four groups. The given amperage of electric current was 500 nA, 2 µA, and 4 µA in groups A, B, and C, respectively. No electric current was given in group D. Results In the first 48 hours, colonies only appeared in groups A and B (500 nA and 2 µA exposure). Colonies in group A (500 nA) were denser. Group C (4 µA) plates showed a barely visible film of fungus after 96 hours of incubation. Fungal growth became visible after 144 hours in the control group. Conclusion Lower intensities of electric current caused faster fungal growth within the amperage range used in this study. Based on these results, further studies with a larger sample size, various fungal species, and various intensities of electric stimulation should be conducted. PMID:27746636

  11. Investigating the Place and Meaning of "Physical Education" to Preschool Children: Methodological Lessons from a Research Study

    Science.gov (United States)

    McEvilly, Nollaig

    2015-01-01

    Preschool physical education has not been extensively researched. Furthermore, research in physical activity and physical education rarely seeks young children's perspectives. The current paper focuses on one aspect of a post-structural study concerned with investigating the place and meaning of "physical education" to practitioners and…

  12. Experimental Investigation and Modelling for the Optimisation of Conduction Cooled HTS Hybrid Current Leads for SMES

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    It′s important that HTS tapes have lower thermal conductivity and higher transversal resistivity in order to reduce the heat leaks conducted along the tapes and AC losses in the high temperature superconducting system conduction-cooled by GM coolers. This paper presents an experimental investigation into the effects of pure Ag and AgAu alloys sheath materials on the properties of Bi(2223) multifilamentary tapes and the optimisation of conduction-cooled hybrid current leads made from copper and Bi(2223)/Ag or Bi(2223)/AgAu tapes. The thermal conductivity of the tapes were measured by cryogenic steady heat flux method and the resistance was measured by using standard DC four-probe method at low temperature. The results showed that the reduction of thermal conductivity by the addition of Au into the sheath material of Bi(2223) tapes was 650%, 750% and 850% lower than that of pure Ag sheathed Bi(2223) tapes and the increase of resistivity was 4.9, 10 and 19.4 times higher than that of pure Ag for the addition of 2.20%, 5.70% and 10.70%Au(atom ratio) respectively. And the study also attempts to optimise thermodynamically the conduction-cooled hybrid current lead by using a developed model, which took the irreversibility of commercial GM coolers, the contact resistance and thermal conductance into account. Predictions from the model showed that AgAu alloys were suitable candidate materials to replace Ag as sheath material of Bi(2223) tapes applied in HTS current leads. In addition, Bi(2223)/AgAu was a suitable material to be applied as the HTS section of hybrid current leads in conduction-cooled superconducting electric systems.

  13. Investigation of properties of human epidermal membrane under constant conductance alternating current iontophoresis.

    Science.gov (United States)

    Zhu, Honggang; Peck, Kendall D; Miller, David J; Liddell, Mark R; Yan, Guang; Higuchi, William I; Li, S Kevin

    2003-04-14

    Previous studies in our laboratory have shown that enhanced, constant permeant fluxes across human skin can be achieved by applying an alternating current (AC) to maintain skin electrical conductance at a constant level. Relative to conventional direct current (DC) iontophoresis, for which current is maintained at a constant level, this newly developed constant conductance alternating current (CCAC) method achieves constant fluxes with less inter- and intra-sample variability. The present study focused upon further investigating the permeability properties of human skin during CCAC iontophoresis at a variety of target resistance/conductance values. A three-stage experimental protocol was used with flux measurements determined on 3 consecutive days. Stage I was an AC only protocol (symmetrical AC square-wave signal), stage II was an AC plus DC protocol (AC square-wave with DC offset voltage), and stage III was a repeat of stage I. During this three-stage protocol, the skin electrical resistance was maintained at a constant target value by manually adjusting the applied AC voltage. Radiolabeled mannitol and urea were model permeants in all experiments. Their fluxes were determined and used to characterize the permeability properties of human skin. The results from the present study established that: (i) the CCAC protocol made it possible to reduce HEM electrical resistance to different target levels as low as 0.8 kOmega cm(2) and maintain the specific resistance level throughout the flux experiment, (ii) permeant fluxes are proportional to skin electrical conductance, (iii) under the studied CCAC passive conditions, membrane pore size tends to increase as skin resistance decreases, and (iv) as the membrane breaks down, its pore sizes become larger.

  14. Investigation and Research on Current Economic Environment Problems in Rural Areas in More Developed Towns--Take Hu'nan Shaodong Liuze Town as an example%当前经济较发达地区农村乡镇环境问题的调查与研究--以湖南省邵东县流泽镇为例

    Institute of Scientific and Technical Information of China (English)

    陈波; 曾方荣

    2014-01-01

    With the development of urbanization, industrialization, the rural environment pollution problem increasingly prominent. In order to further understand the current rural environment pollution and treatment status. We have investigated the weeklong on Liu Ze town in Shao Dong County of Hunan province. Through the survey found that as the economy is relatively developed township rural pollution increasing, the performance in pollution sources is increasing, living garbage, pollutant treatment facilities and other issues, the cause of these problems is, etc. In view of the current rural environmental problems, the countermeasures we should strengthen management, strict law enforcement, increasing investment, to award to promote governance and the comprehensive improvement of multi-pronged.%随着城镇化、工业化发展,农村环境污染问题日益突出。为进一步了解当前农村环境污染和整治状况,我们对湖南省邵东县流泽镇进行了为期一星期的调查。通过调查发现,作为经济较发达乡镇农村污染不断加剧,表现在污染源日益增多、生活垃圾困扰大、污染物处理设施落后等问题,造成这些问题原因是多方面的。针对当前农村环境问题,解决对策应从加强管理、严格执法、加大投入、以奖促治、综合整治等多管齐下入手。

  15. Communicating Research Through Student Involvement in Phenological Investigations

    Science.gov (United States)

    Sparrow, E. B.; Kopplin, M.; Gazal, R. M.; Robin, J. H.; Boger, R. A.

    2011-12-01

    Phenology plays a key role in the environment and ecosystem. Primary and secondary students around the world have been collecting vegetation phenology data and contributing to ongoing scientific investigations. They have increased research capacity by increasing spatial coverage of ground observations that can be useful for validation of remotely sensed data. The green-up and green-down phenology measurement protocols developed at the University of Alaska Fairbanks (UAF) as part of the Global Learning and Observations to Benefit the Environment (GLOBE) program, have been used in more than 250 schools in over 20 countries. In addition to contributing their data, students have conducted their own investigations and presented them at science fairs and symposiums, and international conferences. An elementary school student in Alaska conducted a comprehensive study on the green-down rates of native and introduced trees and shrubs. Her project earned her a one-year college scholarship at UAF. Students from the Model Secondary School for the Deaf in Washington, D. C. and from the Indiana School for the Deaf collaborated on a comparative green-up study, and were chosen to present at an international conference where students from more than 20 countries participated. Similarly, students in Thailand presented at national conferences, their studies such as "The Relationship between Environmental Conditions and Green-down of Teak Trees (Tectona grandis L.)" at Roong Aroon School, Bangkok and "The Comparison of Budburst and Green-up of Leab Trees (Ficus infectoria Roxb.) at Rob Wiang and Mae Khao Tom Sub-district in Chiang Rai Province". Some challenges in engaging students in phenological studies include the mismatch in timing of the start and end of the plant growing season with that of the school year in northern latitudes and the need for scientists and teachers to work with students to ensure accurate measurements. However these are outweighed by benefits to the scientists

  16. Technical support to the Solvent Refined Coal (SRC) demonstration projects: assessment of current research and development

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, M.S.; Rodgers, B.R.; Brown, C.H.; Carlson, P.K.; Gambill, W.R.; Gilliam, T.M.; Holmes, J.M.; Krishnan, R.P.; Parsly, L.F.

    1980-12-01

    A program to demonstrate Solvent Refined Coal (SRC) technology has been initiated by the US Department of Energy (DOE) in partnership with two industrial groups. Project management responsibility has been assigned to the Oak Ridge Operations Office (ORO) of DOE. ORO requested that the Oak Ridge National Laboratory assess current research and development (R and D) activities and develop recommendations for those activities that might contribute to successful completion of the SRC demonstration plant projects. The objectives of this final report are to discuss in detail the problem areas in SRC; to discuss the current and planned R and D investigations relevant to the problems identified; and to suggest appropriate R and D activities in support of designs for the SRC demonstration plants. Four types of R and D activities are suggested: continuation of present and planned activities; coordination of activities and results, present and proposed; extension/redirection of activities not involving major equipment purchase or modifications; and new activities. Important examples of the first type of activity include continuation of fired heater, slurry rheology, and slurry mixing studies at Ft. Lewis. Among the second type of activity, coordination of data acquisition and interpretation is recommended in the areas of heat transfer, vapor/liquid equilibria, and physical properties. Principal examples of recommendations for extension/redirection include screening studies at laboratory scale on the use of carbonaceous precoat (e.g., anthracite) infiltration, and 15- to 30-day continuous tests of the Texaco gasifier at the Texaco Montebello facility (using SRC residues).

  17. Reviewing current knowledge in snatch performance and technique: the need for future directions in applied research.

    Science.gov (United States)

    Ho, Lester K W; Lorenzen, Christian; Wilson, Cameron J; Saunders, John E; Williams, Morgan D

    2014-02-01

    This is a review of current research trends in weightlifting literature relating to the understanding of technique and its role in successful snatch performance. Reference to the world records in the snatch from the 1960s onwards indicates little progress across all weight categories. With such mediocre advances in performance at the International level, there is a need to better understand how snatch technique can improve performance even if only by a small margin. Methods of data acquisition for technical analysis of the snatch have involved mostly 2-dimensional barbell and joint kinematics. Although key variables which play a role in the successful outcome of a snatch lift have been heavily investigated, few studies have combined variables relating both the barbell and the weightlifter in their analyses. This suggests the need for a more detailed approach integrating both barbell-related and weightlifter-related data to enhance understanding of the mechanics of a successful lift. Currently, with the aid of technical advances in motion analysis, data acquisition, and methods of analysis, a more accurate representation of the movement can be provided. Better ways of understanding the key characteristics of technique in the snatch could provide the opportunity for more effective individualized feedback from the coach to the athlete, which should in turn lead to improved performance in competition.

  18. Digital information and communication networks and scientific research substance: An investigation of meteorology

    Science.gov (United States)

    Shen, Yi

    This study investigated research meteorologists' current usage and evaluation of information and communication technologies (ICT) in performing research tasks and the current relationship between meteorologists' ICT use and content characteristics of their research outputs. It surveyed research meteorologists working in three NOAA funded research institutes based at universities. Follow-up interviews with two selective samples of the survey participants were conducted to provide additional evidence to survey results and make suggestions for future measurement development work. Multiple regression analysis was performed to test the hypothesized relationships between meteorologists' ICT use and two substantive characteristics of their research---data integration and intra-/interdisciplinarity. Descriptive statistics were calculated to discern inferences of the scientists' current state of use and their degree of satisfaction with ICT tools. Follow-up interviews were transcribed and analyzed qualitatively with open coding and axial coding. The study findings contradicted the two assumptions of ICT effects on meteorological research by showing that the greater frequency of networked ICT use is not significantly associated with either greater data integration in research analysis, or greater intra- or interdisciplinary research. The major ICT barrier is the lack of a data and information infrastructure and support system for integrated, standardized, specialized, and easily accessible data and information from distributed servers. Suggestions were provided on the improvements of technical, social, political, and educational settings to promote large-scale date integration and intra-/interdisciplinary research. By moving further from theoretical assumptions to practical examinations, the research findings provide empirical evidence of Bowker's theories on the social shaping and social impact of infrastructure in sciences and affirmed some of Bowker's arguments regarding

  19. Developing a line of investigation using educational design research

    NARCIS (Netherlands)

    McKenney, Susan; Reeves, Thomas

    2015-01-01

    Design-Based Research (DBR), Educational Design Research (EDR) and DBIR (Design-Based Implementation Research) share the dual aims of (1) deriving new knowledge through (2) the design and implementation of solutions to problems in educational practice. This family of research approaches involves int

  20. A Review of Research on Metacognition in Science Education: Current and Future Directions

    Science.gov (United States)

    Zohar, Anat; Barzilai, Sarit

    2013-01-01

    The goal of this study is to map the current state of research in the field of metacognition in science education, to identify key trends, and to discern areas and questions for future research. We conducted a systematic analysis of 178 studies published in peer-reviewed journals in the years 2000-2012 and indexed in the ERIC database. The…

  1. Research of resisting of the biological active point for constant and alternative current

    Directory of Open Access Journals (Sweden)

    S. N. Peregudov

    2008-05-01

    Full Text Available Is conducted research of resistance of biologically active point (BAT on a direct and variable current. Research results are presented. The estimation of intercommunication between resistance of skin and by an electromagnetic radiation in BAT is done. Is shown possibility of the use of experimental information for diagnostics of the state of human to the organism.

  2. Mindfulness for Children in Public Schools: Current Research and Developmental Issues to Consider

    Science.gov (United States)

    Chadwick, Jeanne; Gelbar, Nicholas W.

    2016-01-01

    Mindfulness-based interventions have increased in popularity over the past decade and interest continues to increase in the potential to use mindfulness-based interventions in schools. The current research concerning school-based mindfulness-based interventions is reviewed in this article. This research base is fragmented, as most of the studies…

  3. A Review of Research on Metacognition in Science Education: Current and Future Directions

    Science.gov (United States)

    Zohar, Anat; Barzilai, Sarit

    2013-01-01

    The goal of this study is to map the current state of research in the field of metacognition in science education, to identify key trends, and to discern areas and questions for future research. We conducted a systematic analysis of 178 studies published in peer-reviewed journals in the years 2000-2012 and indexed in the ERIC database. The…

  4. Current research trends and perspectives on materials-based hydrogen storage solutions: A critical review

    CSIR Research Space (South Africa)

    Ren, Jianwei

    2016-01-01

    Full Text Available Effective hydrogen storage solutions have been pursued for decades, and materials-based hydrogen storage is a research frontier of much current interest. Yet, no researched materials to date have come close to the DOE 2020 targets for hydrogen...

  5. The Focus of Current HCI Research in Usability Evaluation and Feedback

    DEFF Research Database (Denmark)

    Høegh, Rune Thaarup

    2007-01-01

    This paper presents the findings from a systematic literature study of the research on usability evaluation and feedback. The literature study covers the papers published from five key human-computer interaction journals for a period of four years, and depicts the most current research within...

  6. The causal relationship between Foreign Direct Investment and Current Account: an empirical investigation for Pakistan economy

    Directory of Open Access Journals (Sweden)

    Muhammad ASIM

    2013-08-01

    Full Text Available This paper investigates relationship between FDI and current account (CA in Pakistan using the Johansen-Juselius cointegration technique and the Granger causality test. The study results indicate that FDI and CA are cointegrated and thus exhibit a reliable long run relationship. The Granger causality test findings indicate that the causality between FDI and CA is uni-directional. However, there is no short run causality from FDI to CA and vice versa. Therefore, as a policy implication that FDI inflows may cause to the deterioration of the balance of payments in the long run should be taken into account when policy makers decide to implement policies to attract foreign investors.

  7. Current Research Activities in Drive System Technology in Support of the NASA Rotorcraft Program

    Science.gov (United States)

    Handschuh, Robert F.; Zakrajsek, James J.

    2006-01-01

    Drive system technology is a key area for improving rotorcraft performance, noise/vibration reduction, and reducing operational and manufacturing costs. An overview of current research areas that support the NASA Rotorcraft Program will be provided. Work in drive system technology is mainly focused within three research areas: advanced components, thermal behavior/emergency lubrication system operation, and diagnostics/prognostics (also known as Health and Usage Monitoring Systems (HUMS)). Current research activities in each of these activities will be presented. Also, an overview of the conceptual drive system requirements and possible arrangements for the Heavy Lift Rotorcraft program will be reviewed.

  8. [Resource activation in clinical psychology and psychotherapy: review of theoretical issues and current research].

    Science.gov (United States)

    Groß, L J; Stemmler, M; de Zwaan, M

    2012-08-01

    This review summarises theoretical issues and current research on working with clients' resources and strengths in clinical psychology and psychotherapy. Resource activation is considered as an important common factor in psychotherapy. In general, resource activation means an explicit focus on resources, strengths and potentials of the clients. After defining the term resources, considerations with regard to therapeutic attitude, principles of resource activation, approaches to resource diagnostics and different research strategies are presented. Current research focuses especially on the relation between resource activation and process variables in out-patient treatment.

  9. INSTITUTIONALISM AND INFORMATION SYSTEMS: CURRENT STATE OF THE ART AND POSITION OF FRENCH RESEARCH

    Directory of Open Access Journals (Sweden)

    Rolande Marciniak

    2009-10-01

    Full Text Available The various currents of institutionalism are used in management science, particularly in the area of information systems. Richard Scott's global model is a fertile framework for the analysis of institutional research. First, we will study the contributions of French research to institutionalism. Then, returning to the fundamentals of information systems (IS, we will show that the interaction between institutions and IS can be analysed via the notion of formal and informal rules. Research carried out at the University of Paris

  10. Investigation of pulsed eddy current probes for detection of defects in riveted structures

    Science.gov (United States)

    Yang, Binfeng; Zhang, Hui; Kang, Zhibin; Wang, Xiaofeng

    2013-09-01

    The fatigue crack is the threat to integrity and safety of fuselage lap-joints. Quantification of fatigue cracks by designing and utilisation of an optimised electromagnetic nondestructive evaluation probe can insure the flight safety of aircrafts. In this paper, pulsed eddy current (PEC) for detection and characterisation of fatigue cracks is investigated. The principle of PEC is analysed first, from which four different models of PEC probes are simulated in ANSYS. The signal features, namely zero-crossing time, zero-crossing frequency and peak value are extracted from the time and frequency domains in an effort to qualitatively compare the crack detectability of the four models. The sensitivities of the different probes to cracks are analysed quantitatively. The difference in detectability among the probes is investigated based on the working principle. Simulation results show that the probe consisting of two horizontal detecting coils along with a magnetic field shield focusing the flux has the highest detectability. The conclusions derived from the simulation study are also validated by experiments.

  11. Investigation of Characteristics of Large dB/dt for Geomagnetically Induced Currents

    Science.gov (United States)

    Munoz, D.; Ngwira, C.; Damas, M. C.

    2016-12-01

    When geomagnetically induced currents (GICs) flow through electrical networks, they become a potential threat for electrical power systems. Changes in the geomagnetic field (dB/dt) during severe geomagnetic disturbances are the main sources of GICs. These dB/dt phenomena were studied by selecting 24 strong geomagnetic storms with Dst ≤ - 150 nT. ACE spacecraft solar wind data: flow speed, proton density, By and Bz IMF components of the solar wind were correlated with measurements of the magnetic field detected on ground stations at different latitudes. This article reports characteristics of the solar wind during time intervals of large changes in the horizontal geomagnetic field with a threshold of dB/dt ≥ ± 20 nT/min for the 24 geomagnetic storms. The results of this investigation can help scientists to understand the mechanisms responsible for causing large magnetic field variations in order to predict and mitigate possible large events in the future, which is critical for our society that relies constantly on electricity for livelihood and security. In addition, this ongoing project will continue to investigate electron flux response before, during, and after large changes in geomagnetic field.

  12. 新媒体背景下大学生媒体素养现状调查研究--以河北省部分高校学生为例%Investigation and Research on the Current Situation of College Students' Media Literacy in New Media Back-ground:A Case Study on Some College Students in Hebei Province

    Institute of Scientific and Technical Information of China (English)

    王新; 田明; 李岩芳

    2015-01-01

    When emerging media, such as mobile network, tablet computers, smartphones, , are bringing convenience to college students' life and learning, they also exert certain negative influ-ence. In today's rapid developing emerging media, a pressing matter of the moment for colleges is to strengthen the media liter-acy education of college students. Through investigating the me-dia literacy of some college students in Hebei Province, this pa-per intends to learn about the current situation of college stu-dents' media literacy in Hebei Province, and on this basis, it pro-vides relevant strategies to strengthen the media literacy educa-tion of college students in Hebei Province.%移动网络、平板电脑、智能手机等新兴媒体在给大学生的生活与学习带来便利的同时,也带来了一定的负面影响。在新兴媒体迅速发展的今天,高等院校的当务之急就是要加强大学生媒体素养教育。本文通过对河北省部分高校大学生媒体素养进行调查,了解河北省大学生媒体素养现状,在此基础上,为加强我省大学生媒体素养教育提供相关策略。

  13. Research on Digital Output Verification Technology of Electronic DC Current Transformer

    Science.gov (United States)

    Chen, Yuanjie; Wang, Bin; Hu, Haoliang; Xiong, Qianzhu; Yang, Chunyan

    2017-05-01

    Aiming at the error of calibration system when conducting field calibration by electronic DC current transformer’s digital calibration system, an electronic DC current transformer’s digital calibration system based on protocol conversion is proposed and researched. Data frames outputted from merging unit are collected and converted by the system, the digital synchronization is realized by using the synchronous clock device to trigger the second pulse, and it is verified by the virtual instrument design software. The field calibration is conducted to some converter station digital dc current transformer under the rated current of 500A by using the calibration system. By calibrating and analyzing errors, the error is less than 0.075% when tested current is more than 40% of the rated current. According the standard in literature[1], performance of the calibration system is perfect, measured results perfectly meet the requirements of design, and the calibration system has great practical application value.

  14. Fracture detection and mapping for geothermal reservoir definition: an assessment of current technology, research, and research needs

    Energy Technology Data Exchange (ETDEWEB)

    Goldstein, N.E.

    1984-11-01

    The detection and mapping of fractures and other zones of high permeability, whether natural or manmade, has been a subject of considerable economic and scientific interest to the pertroleum industry and to the geothermal community. Research related to fractured geothermal reservoirs has been conducted under several past DOE geothermal energy development programs. In this paper we review the present state of technology in fracture detection and mapping. We outline the major problems and limitations of the ''conventional'' techniques, and current research in new technologies. We also present research needs.

  15. An Official American Thoracic Society Research Statement : Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling

    NARCIS (Netherlands)

    Prakash, Y S; Halayko, Andrew J; Gosens, Reinoud; Panettieri Jr., Reynold A; Camoretti-Mercado, Blanca; Penn, Raymond B; Burgess, Janette K

    2017-01-01

    BACKGROUND: Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and

  16. An Official American Thoracic Society Research Statement : Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling

    NARCIS (Netherlands)

    Prakash, Y S; Halayko, Andrew J; Gosens, Reinoud; Panettieri Jr., Reynold A; Camoretti-Mercado, Blanca; Penn, Raymond B; Burgess, Janette K

    2017-01-01

    BACKGROUND: Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and regulato

  17. Developing independent investigators for clinical research relevant for Africa

    LENUS (Irish Health Repository)

    Manabe, Yukari C

    2011-12-29

    Abstract Sustainable research capacity building requires training individuals at multiple levels within a supportive institutional infrastructure to develop a critical mass of independent researchers. At many African medical institutions, a PhD is important for academic promotion and is, therefore, an important focal area for capacity building programs. We examine the training at the Infectious Diseases Institute (IDI) as a model for in-country training based on systems capacity building and attention to the academic environment. PhD training in Africa should provide a strong research foundation for individuals to perform independent, original research and to mentor others. Training the next generation of researchers within excellent indigenous academic centers of excellence with strong institutional infrastructure will empower trainees to ask regionally relevant research questions that will benefit Africans.

  18. How to survive in research: advice for the novice investigator.

    Science.gov (United States)

    Siskind, Dan; Parker, Stephen; Loi, Samantha; Looi, Jeffrey C; Macfarlane, Matthew D; Merry, Sally; Smith, Geoff; Kisely, Steve

    2015-02-01

    This paper, written by the RANZCP Committee for Research, provides an outline for how to survive in research, considering the ingredients likely to contribute to success, the role of supportive structures and the expected challenges. Learning how to survive in research is relevant for both trainees and for Fellows undertaking research at any stage of their career. Intellectual curiosity, perseverance, frustration tolerance, patience and humility are key for success as a researcher. Selection of the right supervisor is important, as is development and maintenance of a good working supervisor/supervisee relationship. The personal benefits of undertaking research include flexibility in work hours, and improved skills in writing, oral presentations, objectivity, critical thinking, problem solving and project management. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  19. Current Situation Investigation and Countermeasure Research on the Customer Satisfaction of the Business Expansion of Zhaoqing Power Supply Bureau%肇庆市供电局业扩客户满意度现状调查及对策研究

    Institute of Scientific and Technical Information of China (English)

    周丽; 倪玉琳

    2016-01-01

    In the electricity business of power supply enterprise, the business expansion project is field most easy to occur human power, relative power and the situation of abusing the power to pursue personal interests. In recent years, the "three designations" of the installtion of business expansion have become the focus of concern and the hot spots of complaints, which directly affect the image of the power supply business and the interests of users. In this regard, the research group investigates the customer satisfaction of the business expansion of Zhaoqing Power Supply Bureau and puts forward the countermeasures and suggestions for the existing problems to help power supply enterprises improve customer satisfaction of the business expansion.%在供电企业的电力业务中,业扩项目是最容易产生人情电、关系电、以电谋私的领域。近年来,业扩报装“三指定”等问题,已成为广大客户关心的重点和投诉的热点,这直接影响到供电企业的形象和用户的利益。对此,课题组对肇庆市供电局的业扩客户满意度进行了调查,并针对存在的问题提出了解决对策和建议,以期对供电企业提高业扩客户满意度提供帮助。

  20. Data standards for clinical research data collection forms: current status and challenges.

    Science.gov (United States)

    Richesson, Rachel L; Nadkarni, Prakash

    2011-05-01

    Case report forms (CRFs) are used for structured-data collection in clinical research studies. Existing CRF-related standards encompass structural features of forms and data items, content standards, and specifications for using terminologies. This paper reviews existing standards and discusses their current limitations. Because clinical research is highly protocol-specific, forms-development processes are more easily standardized than is CRF content. Tools that support retrieval and reuse of existing items will enable standards adoption in clinical research applications. Such tools will depend upon formal relationships between items and terminological standards. Future standards adoption will depend upon standardized approaches for bridging generic structural standards and domain-specific content standards. Clinical research informatics can help define tools requirements in terms of workflow support for research activities, reconcile the perspectives of varied clinical research stakeholders, and coordinate standards efforts toward interoperability across healthcare and research data collection.

  1. Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research.

    Science.gov (United States)

    van Asselt, Thea; Ramaekers, Bram; Corro Ramos, Isaac; Joore, Manuela; Al, Maiwenn; Lesman-Leegte, Ivonne; Postma, Maarten; Vemer, Pepijn; Feenstra, Talitha

    2017-09-20

    The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses; and (2) developing a costing tool to support reviewers of grant proposals in assessing whether the proposed budget is realistic. For granted study proposals from the Netherlands Organization for Health Research and Development (ZonMw), type of study, potential cost drivers, proposed budget, and general characteristics were extracted. Regression analysis was conducted in an attempt to generate a 'predicted budget' for certain combinations of cost drivers, for implementation in the costing tool. Of 133 drug-related research grant proposals, 74 were included for complete data extraction. Because an association between cost drivers and budgets was not confirmed, we could not generate a predicted budget based on regression analysis, but only historic reference budgets given certain study characteristics. The costing tool was designed accordingly, i.e. with given selection criteria the tool returns the range of budgets in comparable studies. This range can be used in VOI analysis to estimate whether the expected net benefit of sampling will be positive to decide upon the net value of future research. The absence of association between study characteristics and budgets may indicate inconsistencies in the budgeting or granting process. Nonetheless, the tool generates useful information on historical budgets, and the option to formally relate VOI to budgets. To our knowledge, this is the first attempt at creating such a tool, which can be complemented with new studies being granted, enlarging the underlying database and keeping estimates up to date.

  2. Current research at Neal Smith National Wildlife Refuge as of June 3, 2005

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is a list of research projects in progress at Neal Smith National Wildlife Refuge as of June 3, 2005. For each project, the principle investigator, the...

  3. Informed consent in human subject research: a comparison of current international and Nigerian guidelines.

    Science.gov (United States)

    Fadare, Joseph O; Porteri, Corinna

    2010-03-01

    Informed consent is a basic requirement for the conduct of ethical research involving human subjects. Currently, the Helsinki Declaration of the World Medical Association and the International Ethical Guidelines for Biomedical Research of the Council for International Organizations of Medical Sciences (CIOMS) are widely accepted as international codes regulating human subject research and the informed consent sections of these documents are quite important. Debates on the applicability of these guidelines in different socio-cultural settings are ongoing and many workers have advocated the need for national or regional guidelines. Nigeria, a developing country, has recently adopted its national guideline regulating human subject research: the National Health Research Ethics Committee (NHREC) code. A content analysis of the three guidelines was done to see if the Nigerian guidelines confer any additional protection for research subjects. The concept of a Community Advisory Committee in the Nigerian guideline is a novel one that emphasizes research as a community burden and should promote a form of "research friendship" to foster the welfare of research participants. There is also the need for a regular update of the NHREC code so as to address some issues that were not considered in its current version.

  4. Computational intelligence in gait research: a perspective on current applications and future challenges.

    Science.gov (United States)

    Lai, Daniel T H; Begg, Rezaul K; Palaniswami, Marimuthu

    2009-09-01

    Our mobility is an important daily requirement so much so that any disruption to it severely degrades our perceived quality of life. Studies in gait and human movement sciences, therefore, play a significant role in maintaining the well-being of our mobility. Current gait analysis involves numerous interdependent gait parameters that are difficult to adequately interpret due to the large volume of recorded data and lengthy assessment times in gait laboratories. A proposed solution to these problems is computational intelligence (CI), which is an emerging paradigm in biomedical engineering most notably in pathology detection and prosthesis design. The integration of CI technology in gait systems facilitates studies in disorders caused by lower limb defects, cerebral disorders, and aging effects by learning data relationships through a combination of signal processing and machine learning techniques. Learning paradigms, such as supervised learning, unsupervised learning, and fuzzy and evolutionary algorithms, provide advanced modeling capabilities for biomechanical systems that in the past have relied heavily on statistical analysis. CI offers the ability to investigate nonlinear data relationships, enhance data interpretation, design more efficient diagnostic methods, and extrapolate model functionality. These are envisioned to result in more cost-effective, efficient, and easy-to-use systems, which would address global shortages in medical personnel and rising medical costs. This paper surveys current signal processing and CI methodologies followed by gait applications ranging from normal gait studies and disorder detection to artificial gait simulation. We review recent systems focusing on the existing challenges and issues involved in making them successful. We also examine new research in sensor technologies for gait that could be combined with these intelligent systems to develop more effective healthcare solutions.

  5. Research on Measurement of Bed Shear Stress Under WaveCurrent Interaction

    Institute of Scientific and Technical Information of China (English)

    徐华; 夏云峰; 张世钊马炳和; 郝思禹; 杜德军

    2015-01-01

    The movement of sediment in estuary and on coast is directly restricted by the bed shear stress. Therefore, the research on the basic problem of sediment movement by the bed shear stress is an important way to research the theory of sediment movement. However, there is not a measuring and computing method to measure the bed shear stress under a complicated dynamic effect like wave and current. This paper describes the measurement and test research on the bed shear stress in a long launder of direct current by the new instrument named thermal shearometer based on micro-nanotechnology. As shown by the research results, the thermal shearometer has a high response frequency and strong stability. The measured results can reflect the basic change of the bed shear stress under wave and wave-current effect, and confirm that the method of measuring bed shear stress under wave-current effect with thermal shearometer is feasible. Meanwhile, a preliminary method to compute the shear stress compounded by wave-current is put forward according to the tested and measured results, and then a reference for further study on the basic theory of sediment movement under a complicated dynamic effect is provided.

  6. Mindfulness-Based Stress Reduction and Transcendental Meditation: Current State of Research

    Directory of Open Access Journals (Sweden)

    Adam Holt

    2015-04-01

    Full Text Available This article summarizes the current state of meditation research, specifically focusing on mindfulness-based stress reduction and transcendental meditation. Despite significant methodological problems with the studies reported to date on the subject, there is consistent evidence that meditation can produce changes in the nervous system and physiology of the meditator, and can help with various psychological markers of well-being. Regarding improvement in specific clinical diseases, research is generally mixed and preliminary. Strong recommendations cannot be made based on current evidence, and further studies are needed. In general, there is a stronger body of evidence supporting mindfulness-based stress reduction than for transcendental meditation.

  7. Metabolic Investigation in Gluconacetobacter xylinus and Its Bacterial Cellulose Production under a Direct Current Electric Field.

    Science.gov (United States)

    Liu, Miao; Zhong, Cheng; Zhang, Yu Ming; Xu, Ze Ming; Qiao, Chang Sheng; Jia, Shi Ru

    2016-01-01

    The effects of a direct current (DC) electric field on the growth and metabolism of Gluconacetobacter xylinus were investigated in static culture. When a DC electric field at 10 mA was applied using platinum electrodes to the culture broth, bacterial cellulose (BC) production was promoted in 12 h but was inhibited in the last 12 h as compared to the control (without DC electric field). At the cathode, the presence of the hydrogen generated a strong reductive environment that is beneficial to cell growth. As compared to the control, the activities of glycolysis and tricarboxylic acid cycle, as well as BC productivity were observed to be slightly higher in the first 12 h. However, due to the absence of sufficient oxygen, lactic acid was accumulated from pyruvic acid at 18 h, which was not in favor of BC production. At the anode, DC inhibited cell growth in 6 h when compared to the control. The metabolic activity in G. xylinus was inhibited through the suppression of the tricarboxylic acid cycle and glycolysis. At 18-24 h, cell density was observed to decrease, which might be due to the electrolysis of water that significantly dropped the pH of cultural broth far beyond the optimal range. Meanwhile, metabolites for self-protection were accumulated, for instance proline, glutamic acid, gluconic acid, and fatty acids. Notably, the accumulation of gluconic acid and lactic acid made it a really tough acid stress to cells at the anode and finally led to depression of cell growth.

  8. Investigation of Deep Dielectric Charging and Subsequent Currents on Geosynchronous Spacecraft

    Science.gov (United States)

    1991-12-01

    backscatter+ jh True ambient flux is all of the flux that surrounds the spacecraft. Ambient current density is current/unit area that comes from the ambient...We tacitly assume the currents are constant over the periods of integration. (5) Lnet= nambient +Jenergetic+Jsecondary+ Jbackscatter+ Jhv For the two

  9. An Investigation of the Variety and Complexity of Statistical Methods Used in Current Internal Medicine Literature.

    Science.gov (United States)

    Narayanan, Roshni; Nugent, Rebecca; Nugent, Kenneth

    2015-10-01

    Accreditation Council for Graduate Medical Education guidelines require internal medicine residents to develop skills in the interpretation of medical literature and to understand the principles of research. A necessary component is the ability to understand the statistical methods used and their results, material that is not an in-depth focus of most medical school curricula and residency programs. Given the breadth and depth of the current medical literature and an increasing emphasis on complex, sophisticated statistical analyses, the statistical foundation and education necessary for residents are uncertain. We reviewed the statistical methods and terms used in 49 articles discussed at the journal club in the Department of Internal Medicine residency program at Texas Tech University between January 1, 2013 and June 30, 2013. We collected information on the study type and on the statistical methods used for summarizing and comparing samples, determining the relations between independent variables and dependent variables, and estimating models. We then identified the typical statistics education level at which each term or method is learned. A total of 14 articles came from the Journal of the American Medical Association Internal Medicine, 11 from the New England Journal of Medicine, 6 from the Annals of Internal Medicine, 5 from the Journal of the American Medical Association, and 13 from other journals. Twenty reported randomized controlled trials. Summary statistics included mean values (39 articles), category counts (38), and medians (28). Group comparisons were based on t tests (14 articles), χ2 tests (21), and nonparametric ranking tests (10). The relations between dependent and independent variables were analyzed with simple regression (6 articles), multivariate regression (11), and logistic regression (8). Nine studies reported odds ratios with 95% confidence intervals, and seven analyzed test performance using sensitivity and specificity calculations

  10. Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions.

    Science.gov (United States)

    Guinat, Claire; Gogin, Andrey; Blome, Sandra; Keil, Guenther; Pollin, Reiko; Pfeiffer, Dirk U; Dixon, Linda

    2016-03-12

    African swine fever (ASF) is a major threat to the pig industry in Europe. Since 2007, ASF outbreaks have been ongoing in the Caucasus, Eastern Europe and the Baltic countries, causing severe economic losses for many pig farmers and pork producers. In addition, the number of ASF cases in wild boar populations has dramatically increased over the past few years. Evidence supports direct contact with infectious domestic pigs and wild boars, and consumption of contaminated feed, as the main transmission routes of ASF virus (ASFV) to domestic pigs. However, significant knowledge gaps highlight the urgent need for research to investigate the dynamics of indirect transmission via the environment, the minimal infective doses for contaminated feed ingestion, the probability of effective contacts between infectious wild boars and domestic pigs, the potential for recovered animals to become carriers and a reservoir for transmission, the potential virus persistence within wild boar populations and the influence of human behaviour for the spread of ASFV. This will provide an improved scientific basis to optimise current interventions and develop new tools and strategies to reduce the risk of ASFV transmission to domestic pigs.

  11. Research on the induction motor current signature for centrifugal pump at cavitation condition

    Directory of Open Access Journals (Sweden)

    Yin Luo

    2015-11-01

    Full Text Available Cavitation is a major undesirable phenomenon for centrifugal pump because it can cause hydraulic performance deterioration, pump damage by pitting and material erosion, and structural vibration and noise. Cavitation can appear within the entire range of the operating conditions; therefore, it must be prevented by all means. Sensorless monitoring technology based on motor current signature analysis is non-intrusive and economic for monitoring motor-driven equipment. Thus, this technology is suitable for centrifugal pump systems. The motor current signature for centrifugal pump load at the cavitation condition is the basis of this technology. However, systematic research is lacking on sensorless monitoring technology based on motor current signature. As a result, the tentative exploration for motor current signature at cavitation load was conducted in this study. The results show that the stator current is still a sinusoidal alternating current strictly to the law of sine. Moreover, the root mean square of the current fluctuates because of different flow regimes in the cavitation progress and decreases because vapor density is smaller than water density when cavitation is fully formed. For the stator current spectrum, the noise level, noise distribution, rotation speed, and vane pass frequency components show features in the cavitation process. These indicator indexes change according to the stage of cavitation development. Thus, the motor current signature analysis is found to be a feasible and cost-effective method for the stages of cavitation condition.

  12. Retrospectives, current valences and prospective dimensions of research at the Academy of Public Administration

    Directory of Open Access Journals (Sweden)

    Aurel SÎMBOTEANU

    2016-12-01

    Full Text Available The present study is an attempt to identify the social determinants, which initiated and facilitated the content and evolution of the scientific research of the administrative phenomenon in the Republic of Moldova after the declaration of independence. It also elucidates the current valences and perspectives of this activity in the context of the provisions of the recently adopted Research Strategy of the Academy of Public Administration for the period 2016-2020.

  13. Investigation of the current requirements engineering practices among software developers at the Universiti Utara Malaysia Information Technology (UUMIT) centre

    Science.gov (United States)

    Hussain, Azham; Mkpojiogu, Emmanuel O. C.; Abdullah, Inam

    2016-08-01

    Requirements Engineering (RE) is a systemic and integrated process of eliciting, elaborating, negotiating, validating and managing of the requirements of a system in a software development project. UUM has been supported by various systems developed and maintained by the UUM Information Technology (UUMIT) Centre. The aim of this study was to assess the current requirements engineering practices at UUMIT. The main problem that prompted this research is the lack of studies that support software development activities at the UUMIT. The study is geared at helping UUMIT produce quality but time and cost saving software products by implementing cutting edge and state of the art requirements engineering practices. Also, the study contributes to UUM by identifying the activities needed for software development so that the management will be able to allocate budget to provide adequate and precise training for the software developers. Three variables were investigated: Requirement Description, Requirements Development (comprising: Requirements Elicitation, Requirements Analysis and Negotiation, Requirements Validation), and Requirement Management. The results from the study showed that the current practice of requirement engineering in UUMIT is encouraging, but still need further development and improvement because a few RE practices were seldom practiced.

  14. Neuro-ethics: a research report from Chinese investigation

    Science.gov (United States)

    Hu, Jianfeng; Wang, Tangsheng; Yin, Jinhai; Wang, Yongxia

    2011-10-01

    The neurosciences play an increasingly prominent role in society ,which gives rise to numerous ethical and legal problems. As a result , neuroethics is currently undergoing an explosive growth. Neuroethics , a new field at the intersection of bioethics and neuroscience , is founded on discussions associated with mind and behavior. Broadly defined , neuroethics is concerned with ethical, legal and social policy implications of neuroscience.

  15. The impact on CT dose of the variability in tube current modulation technology: a theoretical investigation

    Science.gov (United States)

    Li, Xiang; Segars, W. Paul; Samei, Ehsan

    2014-08-01

    Body CT scans are routinely performed using tube-current-modulation (TCM) technology. There is notable variability across CT manufacturers in terms of how TCM technology is implemented. Some manufacturers aim to provide uniform image noise across body regions and patient sizes, whereas others aim to provide lower noise for smaller patients. The purpose of this study was to conduct a theoretical investigation to understand how manufacturer-dependent TCM scheme affects organ dose, and to develop a generic approach for assessing organ dose across TCM schemes. The adult reference female extended cardiac-torso (XCAT) phantom was used for this study. A ray-tracing method was developed to calculate the attenuation of the phantom for a given projection angle based on phantom anatomy, CT system geometry, x-ray energy spectrum, and bowtie filter filtration. The tube current (mA) for a given projection angle was then calculated as a log-linear function of the attenuation along that projection. The slope of this function, termed modulation control strength, α, was varied from 0 to 1 to emulate the variability in TCM technology. Using a validated Monte Carlo program, organ dose was simulated for five α values (α = 0, 0.25, 0.5, 0.75, and 1) in the absence and presence of a realistic system mA limit. Organ dose was further normalized by volume-weighted CT dose index (CTDIvol) to obtain conversion factors (h factors) that are relatively independent of system specifics and scan parameters. For both chest and abdomen-pelvis scans and for 24 radiosensitive organs, organ dose conversion factors varied with α, following second-order polynomial equations. This result suggested the need for α-specific organ dose conversion factors (i.e., conversion factors specific to the modulation scheme used). On the other hand, across the full range of α values, organ dose in a TCM scan could be derived from the conversion factors established for a fixed-mA scan (hFIXED). This was possible by

  16. Systematic review of research investigating psychotherapy and information and communication technologies.

    Science.gov (United States)

    Hallberg, Sílvia Cristina Marceliano; Lisboa, Carolina Saraiva de Macedo; de Souza, Déborah Brandão; Mester, Ariela; Braga, Andréia Zambon; Strey, Artur Marques; da Silva, Camila Sartori

    2015-01-01

    Information and communication technologies (ICTs) are devices, services and knowledge that reproduce, process and distribute information. Psychotherapy has been influenced by these technologies, and there is a tendency for their role to expand. To describe the current panorama of the scientific literature on psychotherapy and ICTs. This is a systematic and descriptive review. Searches were run on the electronic databases Biblioteca Virtual em Saude (BVS), PsycINFO, Scopus, PePSIC, ScienceDirect and Index Psi, using the Boolean operator AND and the descriptors psychotherapy, computers, Internet, cell phones and social networks. A considerable volume of empirical research was found, published recently in many different parts of the world, especially in the United States. There is very little Brazilian research on the subject. The majority of the studies identified assess the efficacy or describe the development of techniques and psychotherapies, via ICTs, for prevention, diagnosis or treatment of mental and behavioral disorders. The psychopathology most investigated in this area is depression and it was not possible to draw conclusions on a possible trend for research into the subject to increase. The technology most investigated was the Internet and cognitive-behavioral therapy was the most common theoretical approach in these studies. Systematic reviews of published studies can detect gaps in the research agenda within a specific field of knowledge.

  17. Evolutionary multi-objective optimization: some current research trends and topics that remain to be explored

    Institute of Scientific and Technical Information of China (English)

    Carlos A. COELLO COELLO

    2009-01-01

    This paper provides a short review of some of the main topics in which the current research in evolutionary multi-objective optimization is being focused. The topics discussed include new algorithms, efficiency, relaxed forms of dominance, scalability, and alternative metaheuristics. This discussion motivates some further topics which,from the author's perspective, constitute good potential areas for future research, namely, constraint-handling techniques,incorporation of user's preferences and parameter control,This information is expected to be useful for those interested in pursuing research in this area.

  18. A few perspectives of solar physics research in China - current status and future

    Science.gov (United States)

    Wang, Jingxiu; Ding, Mingde; Ji, Haisheng; Deng, Yuanyong; Liu, Yu; Liu, Zhong; Qu, Zhongquan; Wang, Huaning; Xia, Lidong; Yan, Yihua

    2016-07-01

    Solar physics research as an important discipline in astrophysics in China aims at improving the understanding of origin and variation of solar magnetic field and magnetic activity, and founding the basis for forecast of disastrous space weather. The current review is focused on the solar physics research in China in recent three years. Highlights in scientific research in solar magnetism, magnetic activity, coronal plasma, and space weather forecast are briefly summarized. Key advances in instrument development are reported in some necessary details. Future tendency and working direction are considered and discussed.

  19. Metabolic investigation in Gluconacetobacter xylinus and its bacterial cellulose production under a direct current electric field

    Directory of Open Access Journals (Sweden)

    Miao eLiu

    2016-03-01

    Full Text Available The effects of a direct current (DC electric field on the growth and metabolism of Gluconacetobacter xylinus were investigated in static culture. When a DC electric field at 10 mA was applied using platinum electrodes to the culture broth, bacterial cellulose (BC production was promoted in 12 hours (h but was inhibited in the last 12 h as compared to the control (without DC electric field. At the cathode, the presence of the hydrogen generated a strong reductive environment that is beneficial to cell growth. As compared to the control, the activities of glycolysis and tricarboxylic acid cycle, as well as BC productivity were observed to be slightly higher in the first 12 h. However, due to the absence of sufficient oxygen, lactic acid was accumulated from pyruvic acid at 18 h, which was not in favor of BC production. At the anode, DC inhibited cell growth in 6 h when compared to the control. The metabolic activity in G. xylinus was inhibited through the suppression of the tricarboxylic acid cycle and glycolysis. At 18-24 h, cell density was observed to decrease, which might be due to the electrolysis of water that significantly dropped the pH of cultural broth far beyond the optimal range. Meanwhile, metabolites for self-protection were accumulated, for instance proline, glutamic acid, gluconic acid and fatty acids. Notably, the accumulation of gluconic acid and lactic acid made it a really tough acid stress to cells at the anode and finally led to depression of cell growth.

  20. Introduction to quantitative research methods an investigative approach

    CERN Document Server

    Balnaves, Mark

    2001-01-01

    Introduction to Quantitative Research Methods is a student-friendly introduction to quantitative research methods and basic statistics. It uses a detective theme throughout the text and in multimedia courseware to show how quantitative methods have been used to solve real-life problems. The book focuses on principles and techniques that are appropriate to introductory level courses in media, psychology and sociology. Examples and illustrations are drawn from historical and contemporary research in the social sciences. The multimedia courseware provides tutorial work on sampling, basic statistics, and techniques for seeking information from databases and other sources. The statistics modules can be used as either part of a detective games or directly in teaching and learning. Brief video lessons in SPSS, using real datasets, are also a feature of the CD-ROM.

  1. Introduction to quantitative research methods an investigative approach

    CERN Document Server

    Balnaves, Mark

    2001-01-01

    Introduction to Quantitative Research Methods is a student-friendly introduction to quantitative research methods and basic statistics. It uses a detective theme throughout the text and in multimedia courseware to show how quantitative methods have been used to solve real-life problems. The book focuses on principles and techniques that are appropriate to introductory level courses in media, psychology and sociology. Examples and illustrations are drawn from historical and contemporary research in the social sciences. The multimedia courseware provides tutorial work on sampling, basic statistics, and techniques for seeking information from databases and other sources. The statistics modules can be used as either part of a detective games or directly in teaching and learning. Brief video lessons in SPSS, using real datasets, are also a feature of the CD-ROM.

  2. Review of Current Status and Research Approaches to Nitrogen Pollution in Farmlands

    Institute of Scientific and Technical Information of China (English)

    NIE Sheng-wei; GAO Wang-sheng; CHEN Yuan-quan; SUI Peng; A Egrinya Eneji

    2009-01-01

    In this paper, the history, current status, and research approaches to nitrogen pollution were reviewed using systems analysis and deductions. The seriousness of N pollution world-wide was highlighted and recommendations were made to address the situation. A new hypothesis based on phytoremediation, which means the use of plants to directly or indirectly degrade or remove contaminats from soil and water, was proposed.

  3. Gravitational radiation theory. M.A. Thesis - Rice Univ.; [survey of current research

    Science.gov (United States)

    Wilson, T. L.

    1973-01-01

    A survey is presented of current research in the theory of gravitational radiation. The mathematical structure of gravitational radiation is stressed. Furthermore, the radiation problem is treated independently from other problems in gravitation. The development proceeds candidly through three points of view - scalar, rector, and tensor radiation theory - and the corresponding results are stated.

  4. Current status of neutron activation analysis using the Dalat Nuclear Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen Van Suc; Nguyen Mong Sinh [Nuclear Research Institute, Dalat (Viet Nam)

    1999-10-01

    Neutron activation analysis is one of the most sensitive, rapid, accurated methods for determination of trace elements in different materials. A review is made of the current status of the activities and the results in studying and developing NAA (Neutron Activation Analysis) at the Dalat Nuclear Research Institute and applying this method to different sectors of science and technology in Vietnam. (author)

  5. Current status and progress of research on the management of bean ...

    African Journals Online (AJOL)

    ©2000 National Agricultural Research Organisation. Current status ... Them a in ohj ective of this study was to identify control measures that can reduce the disease on ... practices in controlling root rot was carried out in 1997 for two seasons ...

  6. Fusarium mycotoxins: Current research at the USDA ARS Mycotoxin Prevention unit

    Science.gov (United States)

    Due to the health and economic costs of mycotoxins produced by Fusarium species, there is a compelling need for improved understanding of these fungi, from across diverse perspectives and disciplinary approaches. Current research at the USDA ARS Mycotoxin Prevention unit addresses Fusarium mycotoxin...

  7. Investigation on Current Situation of Health Literacy of College Sports Majors in Gansu and Improving Strategy Research%甘肃高校体育专业大学生健康素养现状调查及提升策略研究

    Institute of Scientific and Technical Information of China (English)

    程晖

    2015-01-01

    In order to understand the status of college sports majors’health literacy in Gansu and to provide basis for promoting their health literacy,the paper uses self -designed ‘Questionnaire on Sports Majors’Health Literacy in Gansu’to investigate its research objects with stratified cluster sampling method.It is found that the proportion of sports majors’health literacy is 7.84%,with the proportion of basic knowledge and concepts, healthy lifestyle and behavior,and basic skills respectively revealed as 21.55%,2.34% and 69.44%;Proportion of having five types of health literacy is respectively as follows:69.25% of safety and first aid;24.11% of primary medical treatment;17.80% of scientific view on health;8.88% of preventing chronic disease;6.19% of preventing infectious disease.The paper concludes that health literacy of sports majors is basically same with national average level and necessary health intervention needs taking to improve health literacy.%为了解甘肃省体育专业大学生具备健康素养状况,为促进该群体健康素养提供依据。本文采用分层整群抽样方法,使用自行设计的《甘肃省体育专业大学生健康素养调查问卷》对调查对象进行调查。结果发现:体育专业大学生具备健康素养的比例是7.84%,具备基本知识和理念、健康生活方式与行为、基本技能三方面素养的比例分别是21.55%,2.34%和69.44%;具备5类健康问题素养比例分别是:安全与急救69.25%,基本医疗24.11%,科学健康观17.80%,慢性病预防素养8.88%和传染病预防素养6.19%。结论体育专业大学生的健康素养和全国平均水平基本一致,应采取必要的健康教育干预,提升健康素养。

  8. The emergence and current performance of a health research system: lessons from Guinea Bissau

    Directory of Open Access Journals (Sweden)

    Kok Maarten O

    2012-02-01

    Full Text Available Abstract Background Little is known about how health research systems (HRS in low-income countries emerge and evolve over time, and how this process relates to their performance. Understanding how HRSs emerge is important for the development of well functioning National Health Research Systems (NHRS. The aim of this study was to assess how the HRS in Guinea Bissau has emerged and evolved over time and how the present system functions. Methods We used a qualitative case-study methodology to explore the emergence and current performance of the HRS, using the NHRS framework. We reviewed documents and carried out 39 in-depth interviews, ranging from health research to policy and practice stakeholders. Using an iterative approach, we undertook a thematic analysis of the data. Results The research practices in Guinea Bissau led to the emergence of a HRS with both local and international links and strong dependencies on international partners and donors. The post-colonial, volatile and resource-dependent context, changes in donor policies, training of local researchers and nature of the research findings influenced how the HRS evolved. Research priorities have mostly been set by 'expatriate' researchers and focused on understanding and reducing child mortality. Research funding is almost exclusively provided by foreign donors and international agencies. The training of Guinean researchers started in the mid-nineties and has since reinforced the links with the health system, broadened the research agenda and enhanced local use of research. While some studies have made an important contribution to global health, the use of research within Guinea Bissau has been constrained by the weak and donor dependent health system, volatile government, top-down policies of international agencies, and the controversial nature of some of the research findings. Conclusions In Guinea Bissau a de facto 'system' of research has emerged through research practices and co

  9. International Immersion in Counselor Education: A Consensual Qualitative Research Investigation

    Science.gov (United States)

    Barden, Sejal M.; Cashwell, Craig S.

    2014-01-01

    This study used consensual qualitative research methodology to examine the phenomenon of international immersion on counselor education students' (N = 10) development and growth. Seven domains emerged from the data (cultural knowledge, empathy, personal and professional impact, process/reflection, relationships, personal characteristics, and…

  10. Interpreting and Reporting Effect Sizes in Research Investigations.

    Science.gov (United States)

    Tapia, Martha; Marsh, George E., II

    Since 1994, the American Psychological Association (APA) has advocated the inclusion of effect size indices in reporting research to elucidate the statistical significance of studies based on sample size. In 2001, the fifth edition of the APA "Publication Manual" stressed the importance of including an index of effect size to clarify…

  11. Naval Arctic Research Laboratory (NARL) Subsurface Containment Berm Investigation

    Science.gov (United States)

    2015-10-01

    The former Navy Arctic Research Laboratory Airstrip Site in Barrow, Alaska, has a history of fuel spills. Various methods have been used to re- mediate ...or [− + −]) were ab- sent directly under the insulation/plywood and on the shoulder areas im- mediately adjacent to the insulation/plywood. The lack

  12. International Immersion in Counselor Education: A Consensual Qualitative Research Investigation

    Science.gov (United States)

    Barden, Sejal M.; Cashwell, Craig S.

    2014-01-01

    This study used consensual qualitative research methodology to examine the phenomenon of international immersion on counselor education students' (N = 10) development and growth. Seven domains emerged from the data (cultural knowledge, empathy, personal and professional impact, process/reflection, relationships, personal characteristics, and…

  13. Research Methods to Investigate Significant Life Experiences: Review and Recommendations

    Science.gov (United States)

    Chawla, Louise

    2006-01-01

    This article reviews different research approaches to understanding the significant experiences that influence peoples environmental concern and behaviour, with an emphasis on identifying the strengths and weaknesses of existing studies. It also reviews relevant findings regarding the validity of autobiographical memory, as memory is the medium…

  14. Investigating the Benefits of Participatory Action Research for Environmental Education

    Science.gov (United States)

    Bywater, Krista

    2014-01-01

    Environmental education (EE) continues to focus on enhancing people's ecological knowledge to encourage sustainable actions. This deficit approach presumes that once informed about environmental harms, people will work towards sustainable solutions for healthy societies. Yet research overwhelmingly demonstrates that knowledge of environmental…

  15. Current Researches on the Methods of Diagnosing Sasang Constitution: An Overview

    Directory of Open Access Journals (Sweden)

    Si-Woo Lee

    2009-01-01

    Full Text Available Sasang constitution diagnosis has traditionally been conducted by a Sasang constitutional medicine (SCM doctor who examines the external appearance, temperament and various symptoms of an individual and then collectively analyzes this information to determine their own constitutions. However, because this process is subjective and not quantitative, many researchers have been attempting to develop objective and reasonable methods of determining constitutions. In Korea, even though a wide range of research regarding SCM has been conducted, most of the work has not been revealed internationally. So in this review, the authors have searched the Journal of Sasang Constitutional Medicine, as well as other Korean domestic journal databases and Pubmed for research regarding modernized constitution diagnosis methods so to provide the understanding of current research state and outlook for future research.

  16. African swine fever virus: current state and future perspectives in vaccine and antiviral research.

    Science.gov (United States)

    Zakaryan, Hovakim; Revilla, Yolanda

    2016-03-15

    African swine fever (ASF) is among the most significant of swine diseases for which no effective vaccines and antivirals are available. The disease, which is endemic in Africa, was introduced to Trans-Caucasian countries and the Russian Federation in 2007, where it remains prevalent today among domestic pigs and wild boars. Although some measures were implemented, ASF continues to pose a global risk for all countries, and thereby highlighting the importance of vaccine and antiviral research. In this review, an overview of research efforts toward the development of effective vaccines during the past decades is presented. As an alternative to vaccine development, the current state in antiviral research against ASFV is also presented. Finally, future perspectives in vaccine and antiviral research giving emphasis on some strategies that may allow researchers to develop effective countermeasures against ASF are discussed.

  17. The Evolution of Current Research Impact Metrics: From Bibliometrics to Altmetrics?

    Science.gov (United States)

    Butler, Joseph S; Kaye, I David; Sebastian, Arjun S; Wagner, Scott C; Morrissey, Patrick B; Schroeder, Gregory D; Kepler, Christopher K; Vaccaro, Alexander R

    2017-03-23

    The prestige of publication has been based on traditional citation metrics, most commonly journal impact factor. However, the Internet has radically changed the speed, flow, and sharing of medical information. Furthermore, the explosion of social media, along with development of popular professional and scientific websites and blogs, has led to the need for alternative metrics, known as altmetrics, to quantify the wider impact of research. We explore the evolution of current research impact metrics and examine the evolving role of altmetrics in measuring the wider impact of research. We suggest that altmetrics used in research evaluation should be part of an informed peer-review process such as traditional metrics. Moreover, results based on altmetrics must not lead to direct decision making about research, but instead, should be used to assist experts in making decisions. Finally, traditional and alternative metrics should complement, not replace, each other in the peer-review process.

  18. Investigation of In Vitro Bone Cell Adhesion and Proliferation on Ti Using Direct Current Stimulation.

    Science.gov (United States)

    Bodhak, Subhadip; Bose, Susmita; Kinsel, William C; Bandyopadhyay, Amit

    2012-12-01

    Our objective was to establish an in vitro cell culture protocol to improve bone cell attachment and proliferation on Ti substrate using direct current stimulation. For this purpose, a custom made electrical stimulator was developed and a varying range of direct currents, from 5 to 25 µA, were used to study the current stimulation effect on bone cells cultured on conducting Ti samples in vitro. Cell-materials interaction was studied for a maximum of 5 days by culturing with human fetal osteoblast cells (hFOB). The direct current was applied in every 8 h time interval and the duration of electrical stimulation was kept constant at 15 min for all cases. In vitro results showed that direct current stimulation significantly favored bone cell attachment and proliferation in comparison to nonstimulated Ti surface. Immunochemistry and confocal microscopy results confirmed that the cell adhesion was most pronounced on 25 µA direct current stimulated Ti surfaces as hFOB cells expressed higher vinculin protein with increasing amount of direct current. Furthermore, MTT assay results established that cells grew 30% higher in number under 25 µA electrical stimulation as compared to nonstimulated Ti surface after 5 days of culture period. In this work we have successfully established a simple and cost effective in vitro protocol offering easy and rapid analysis of bone cell-materials interaction which can be used in promotion of bone cell attachment and growth on Ti substrate using direct current electrical stimulation in an in vitro model.

  19. Investigation of the current break-down phenomena in solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, S.K.; Srinivasamurthy, N.; Agrawal, B.L. [Power Systems Group, ISRO Satellite Centre, Bangalore (India)

    1996-08-15

    Observed reverse current-voltage characteristics of the single crystal silicon and gallium arsenide solar cells have been analyzed. Physical mechanisms behind the junction break-down in silicon cells and current break-down in gallium arsenide cells have been identified. Preliminary estimates of the diffusion capacitance in GaAs cells have been presented

  20. 14 CFR 1275.105 - Conduct of the OIG investigation of research misconduct.

    Science.gov (United States)

    2010-01-01

    ... research misconduct. 1275.105 Section 1275.105 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.105 Conduct of the OIG investigation of research misconduct. (a) The OIG shall make every reasonable effort to complete a NASA research misconduct investigation and...

  1. How Do Clinicians Learn About Knowledge Translation? An Investigation of Current Web-Based Learning Opportunities.

    Science.gov (United States)

    Damarell, Raechel A; Tieman, Jennifer J

    2017-07-13

    Clinicians are important stakeholders in the translation of well-designed research evidence into clinical practice for optimal patient care. However, the application of knowledge translation (KT) theories and processes may present conceptual and practical challenges for clinicians. Online learning platforms are an effective means of delivering KT education, providing an interactive, time-efficient, and affordable alternative to face-to-face education programs. This study investigates the availability and accessibility of online KT learning opportunities for health professionals. It also provides an analysis of the types of resources and associated disciplines retrieved by a range of KT synonyms. We searched a range of bibliographic databases and the Internet (Google advanced option) using 9 KT terms to identify online KT learning resources. To be eligible, resources had to be free, aimed at clinicians, educational in intent, and interactive in design. Each term was searched using two different search engines. The details of the first 100 websites captured per browser (ie, n=200 results per term) were entered into EndNote. Each site was subsequently visited to determine its status as a learning resource. Eligible websites were appraised for quality using the AACODS (Authority, Accuracy, Coverage, Objectivity, Date, Significance) tool. We identified 971 unique websites via our multiple search strategies. Of these, 43 were health-related and educational in intent. Once these sites were evaluated for interactivity, a single website matched our inclusion criteria (Dementia Knowledge Translation Learning Centre). KT is an important but complex system of processes. These processes overlap with knowledge, practice, and improvement processes that go by a range of different names. For clinicians to be informed and competent in KT, they require better access to free learning opportunities. These resources should be designed from the viewpoint of the clinician, presenting KT

  2. Experimental Research of Harmonic Spectrum of Currents at Traction Drive with PMSM

    Directory of Open Access Journals (Sweden)

    J. Novak

    2011-06-01

    Full Text Available The paper deals with the significant results of the experimental research of current harmonic spectrum of traction drive with permanent magnet synchronous motor. The experiments were done on a special workplace with a real traction drive for wheel vehicles. Current harmonic spectrum was analyzed by a specialized device on the base of central measuring station. The knowledge of current marked subharmonic components of stator winding is the most significant finding of experiments. The frequencies of these components are given by multiples of frequency of mechanical speeds. The subharmonic components also pass to input DC current of drive. This fact is important in particular from the point of view of legislative requirements to electromagnetic compatibility of drive with railway interlocking devices.

  3. Updates on Nutraceutical Sleep Therapeutics and Investigational Research

    Directory of Open Access Journals (Sweden)

    Michael Yurcheshen

    2015-01-01

    Full Text Available Approximately 50% of the population will suffer from a sleep disorder over the course of their lifetime. There is increasing interest in nutraceuticals for these conditions. The quality of the evidence for the safety and effectiveness of using these supplements to treat sleep disorders varies substantially. In this review, we discuss the data about the effectiveness and safety of six commonly used plant-based sleep therapeutics: caffeine, chamomile, cherries, kava kava, L-tryptophan, marijuana, and valerian. We explore both historical uses of each substance and the current state of the literature.

  4. Updates on Nutraceutical Sleep Therapeutics and Investigational Research.

    Science.gov (United States)

    Yurcheshen, Michael; Seehuus, Martin; Pigeon, Wilfred

    2015-01-01

    Approximately 50% of the population will suffer from a sleep disorder over the course of their lifetime. There is increasing interest in nutraceuticals for these conditions. The quality of the evidence for the safety and effectiveness of using these supplements to treat sleep disorders varies substantially. In this review, we discuss the data about the effectiveness and safety of six commonly used plant-based sleep therapeutics: caffeine, chamomile, cherries, kava kava, L-tryptophan, marijuana, and valerian. We explore both historical uses of each substance and the current state of the literature.

  5. Research program to investigate the fundamental chemistry of technetium

    Energy Technology Data Exchange (ETDEWEB)

    Shuh, David K.; Lukens, Wayne W.; Burns, Carol J.

    2003-12-19

    The objective of this research is to increase the knowledge of the fundamental technetium chemistry that is necessary to address challenges to the safe, long-term remediation of high-level waste posed by this element. These challenges may be divided into two categories: unexpected behavior of technetium in high-level waste tanks at the Hanford and Savannah River Sites and the behavior of technetium in waste forms.

  6. The Investigative Interview: A Review of Practice and Related Research

    Science.gov (United States)

    1988-11-01

    personal accomplishment that often occurs among individuals who do "people-work" of some kind ( Maslach and Jackson , 1985). Professionals who work in such...with feelings of anger, embarrassment, frustration, fear or despair" ( Maslach & Jackson , 1981b). The primary focus of research on burnout has been to...outcomes (e.g., intention to quit, job satisfaction, turnover) 98 ( Jackson , Schwab, & Schuler, i986; Maslach & Jackson , 1981a, 1981b). The role of sex

  7. Research program to investigate the fundamental chemistry of technetium

    Energy Technology Data Exchange (ETDEWEB)

    Shuh, David K.; Lukens, Wayne W.; Burns, Carol J.

    2003-12-19

    The objective of this research is to increase the knowledge of the fundamental technetium chemistry that is necessary to address challenges to the safe, long-term remediation of high-level waste posed by this element. These challenges may be divided into two categories: unexpected behavior of technetium in high-level waste tanks at the Hanford and Savannah River Sites and the behavior of technetium in waste forms.

  8. A Guide for Explosion and Bombing Scene Investigation. Research Report.

    Science.gov (United States)

    Department of Justice, Washington, DC. National Inst. of Justice.

    This document presents an investigative outline of the tasks that law enforcement personnel should consider at every bombing and explosion scene. The following are among the topics discussed in the guide's seven sections: (1) procuring equipment and tools (safety, general crime scene tools/equipment, scene documentation, evidence collection,…

  9. The value of value of information: best informing research design and prioritization using current methods.

    Science.gov (United States)

    Eckermann, Simon; Karnon, Jon; Willan, Andrew R

    2010-01-01

    Value of information (VOI) methods have been proposed as a systematic approach to inform optimal research design and prioritization. Four related questions arise that VOI methods could address. (i) Is further research for a health technology assessment (HTA) potentially worthwhile? (ii) Is the cost of a given research design less than its expected value? (iii) What is the optimal research design for an HTA? (iv) How can research funding be best prioritized across alternative HTAs? Following Occam's razor, we consider the usefulness of VOI methods in informing questions 1-4 relative to their simplicity of use. Expected value of perfect information (EVPI) with current information, while simple to calculate, is shown to provide neither a necessary nor a sufficient condition to address question 1, given that what EVPI needs to exceed varies with the cost of research design, which can vary from very large down to negligible. Hence, for any given HTA, EVPI does not discriminate, as it can be large and further research not worthwhile or small and further research worthwhile. In contrast, each of questions 1-4 are shown to be fully addressed (necessary and sufficient) where VOI methods are applied to maximize expected value of sample information (EVSI) minus expected costs across designs. In comparing complexity in use of VOI methods, applying the central limit theorem (CLT) simplifies analysis to enable easy estimation of EVSI and optimal overall research design, and has been shown to outperform bootstrapping, particularly with small samples. Consequently, VOI methods applying the CLT to inform optimal overall research design satisfy Occam's razor in both improving decision making and reducing complexity. Furthermore, they enable consideration of relevant decision contexts, including option value and opportunity cost of delay, time, imperfect implementation and optimal design across jurisdictions. More complex VOI methods such as bootstrapping of the expected value of

  10. Research on resistance characteristics of YBCO tape under short-time DC large current impact

    Science.gov (United States)

    Zhang, Zhifeng; Yang, Jiabin; Qiu, Qingquan; Zhang, Guomin; Lin, Liangzhen

    2017-06-01

    Research of the resistance characteristics of YBCO tape under short-time DC large current impact is the foundation of the developing DC superconducting fault current limiter (SFCL) for voltage source converter-based high voltage direct current system (VSC-HVDC), which is one of the valid approaches to solve the problems of renewable energy integration. SFCL can limit DC short-circuit and enhance the interrupting capabilities of DC circuit breakers. In this paper, under short-time DC large current impacts, the resistance features of naked tape of YBCO tape are studied to find the resistance - temperature change rule and the maximum impact current. The influence of insulation for the resistance - temperature characteristics of YBCO tape is studied by comparison tests with naked tape and insulating tape in 77 K. The influence of operating temperature on the tape is also studied under subcooled liquid nitrogen condition. For the current impact security of YBCO tape, the critical current degradation and top temperature are analyzed and worked as judgment standards. The testing results is helpful for in developing SFCL in VSC-HVDC.

  11. Experimental and theoretical investigations on the singularity of the intensity factor of the current in high temperature superconductors

    Science.gov (United States)

    Zhang, Xingyi; Huang, Yi; Zhou, Jun; Zhou, Youhe

    2013-08-01

    This paper presents experimental and analytical investigations into the distribution of current around a through-edge crack located in an infinitely long cylindrical high temperature superconductor (HTS) on the basis of the Bean model. Current distributions around the crack in the HTS without deformation are obtained by a simple conformal mapping. It is shown that the current is singular at the tip of the crack. An intensity factor of the current is introduced to characterize the singularity, the order of which is equal to -1. Additionally, an experimental verification according to the trapped field distributions around the crack is carried out, and the experimental results show little difference with the theoretical analysis.

  12. Investigations of Tracking Phenomena in Silicone Rubber Using Moving Average Current Technique

    Institute of Scientific and Technical Information of China (English)

    R. Sarathi; S. Chandrasekar

    2004-01-01

    In the present work, tracking phenomenon in Silicone rubber material has been studied under AC and DC voltage, with ammonium chloride as a contaminant. It is observed that the tracking is more severe under the DC voltages. The tracking time is less under negative DC compared to the positive DC voltage. The tracking mechanism is explained in detail. The leakage current during the tracking studies was as measured and the moving average technique was adopted to understand the trend in current flow. The leakage current magnitude is high with thermally aged specimens compared to the virgin specimen, irrespective of the type of applied voltage. It is realized that the tracking time and the leakage current magnitude shows an inverse relationship.

  13. Anodic Oxidation of Carbon Steel at High Current Densities and Investigation of Its Corrosion Behavior

    Science.gov (United States)

    Fattah-Alhosseini, Arash; Khan, Hamid Yazdani

    2017-02-01

    This work aims at studying the influence of high current densities on the anodization of carbon steel. Anodic protective coatings were prepared on carbon steel at current densities of 100, 125, and 150 A/dm2 followed by a final heat treatment. Coatings microstructures and morphologies were analyzed using X-ray diffraction (XRD) and scanning electron microscope (SEM). The corrosion resistance of the uncoated carbon steel substrate and the anodic coatings were evaluated in 3.5 wt pct NaCl solution through electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization measurements. The results showed that the anodic oxide coatings which were prepared at higher current densities had thicker coatings as a result of a higher anodic forming voltage. Therefore, the anodized coatings showed better anti-corrosion properties compared to those obtained at lower current densities and the base metal.

  14. INVESTIGATION OF MICROPROCESSOR CURRENT PROTECTION LINES WITH IMPROVED INDICES OF TECHNICAL PERFECTION

    Directory of Open Access Journals (Sweden)

    E. V. Buloichyk

    2014-01-01

    Full Text Available Technical perfection improvement of microprocessor current protection of distribution networks lines is provided by introduction of asymmetrical fault mode determination and fault location functions in the algorithm of its functioning. As a result of computing experiment the basic indices of the technical perfection of current protection have been obtained in the paper. The paper proves high efficiency of the proposed methods that ensure selective and proper operation in the different modes of the controlled line.

  15. Investigating the effects of the interface defects on the gate leakage current in MOSFETs

    Science.gov (United States)

    Mao, Ling-Feng

    2008-08-01

    The effects of the interface defects on the gate leakage current have been numerically modeled. The results demonstrate that the shallow and deep traps have different effects on the dependence relation of the stress-induced leakage current on the oxide electric field in the regime of direct tunneling, whereas both traps keep the same dependence relation in the regime of Fowler-Nordheim tunneling. The results also shows that the stress-induced leakage current will be the largest at a moderate oxide voltage for the electron interface traps but it increases with the decreasing oxide voltage for the hole interface traps. The results illustrate that the stress-induced leakage current strongly depends on the location of the electron interface traps but it weakly depends on the location of the hole interface traps. The increase in the gate leakage current caused by the electron interface traps can predict the increase, then decrease in the stress-induced leakage current, with decreasing oxide thickness, which is observed experimentally. And the electron interface trap level will have a large effect on the peak height and position.

  16. Fuel-coolant interaction (FCI) phenomena in reactor safety. Current understanding and future research needs

    Energy Technology Data Exchange (ETDEWEB)

    Speis, T.P. [Maryland Univ., College Park, MD (United States); Basu, S.

    1998-01-01

    This paper gives an account of the current understanding of fuel-coolant interaction (FCI) phenomena in the context of reactor safety. With increased emphasis on accident management and with emerging in-vessel core melt retention strategies for advanced light water reactor (ALWR) designs, recent interest in FCI has broadened to include an evaluation of potential threats to the integrity of reactor vessel lower head and ex-vessel structural support, as well as the role of FCI in debris quenching and coolability. The current understanding of FCI with regard to these issues is discussed, and future research needs to address the issues from a risk perspective are identified. (author)

  17. Cancer research in need of a scientific revolution: Using 'paradigm shift' as a method of investigation.

    Science.gov (United States)

    Wion, Didier; Appaix, Florence; Burruss, Meriwether; Berger, Francois; van der Sanden, Boudewijn

    2015-09-01

    Despite important human and financial resources and considerable accumulation of scientific publications, patents, and clinical trials, cancer research has been slow in achieving a therapeutic revolution similar to the one that occurred in the last century for infectious diseases. It has been proposed that science proceeds not only by accumulating data but also through paradigm shifts. Here, we propose to use the concept of 'paradigm shift' as a method of investigation when dominant paradigms fail to achieve their promises. The first step in using the 'paradigm shift' method in cancer research requires identifying its founding paradigms. In this review, two of these founding paradigms will be discussed: (i) the reification of cancer as a tumour mass and (ii) the translation of the concepts issued from infectious disease in cancer research. We show how these founding paradigms can generate biases that lead to over-diagnosis and over-treatment and also hamper the development of curative cancer therapies. We apply the 'paradigm shift' method to produce perspective reversals consistent with current experimental evidence. The 'paradigm shift' method enlightens the existence of a tumour physiologic-prophylactic-pathologic continuum. It integrates the target/antitarget concept and that cancer is also an extracellular disease. The 'paradigm shift' method has immediate implications for cancer prevention and therapy. It could be a general method of investigation for other diseases awaiting therapy.

  18. Research program to investigate the fundamental chemistry of technetium

    Energy Technology Data Exchange (ETDEWEB)

    McKeown, David A.; Buechele, Andrew C.; Lukens, Wayne W.; Muller, Isabelle S.; Shuh, David K.; Pegg, Ian L.

    2007-10-12

    The objective of this research is to increase the knowledge of the fundamental technetium chemistry necessary to address challenges to the safe, long-term disposal of high-level nuclear waste posed by this element. The primary issues examined during the course of this project were the behavior of technetium and its surrogate rhenium during waste vitrification and glass corrosion. Since the redox behavior of technetium can play a large role in determining its volatility, one goal of this research was to better understand the behavior of technetium in glass as a function of the redox potential of the glass melt. In addition, the behavior of rhenium was examined, since rhenium is commonly used as a surrogate for technetium in waste vitrification studies. A number of glasses similar to Hanford Low Activity Waste (LAW) glasses were prepared under controlled atmospheres. The redox state of the glass was determined from the Fe(II)/Fe(III) ratio in the cooled glass, and the speciation of technetium and rhenium was determined by x-ray absorption fine structure (XAFS) spectroscopy. The behavior of rhenium and technetium during glass alteration was also examined using the vapor hydration test (VHT).

  19. Improving performance in golf: current research and implications from a clinical perspective

    Directory of Open Access Journals (Sweden)

    Kerrie Evans

    2015-10-01

    Full Text Available ABSTRACTGolf, a global sport enjoyed by people of all ages and abilities, involves relatively long periods of low intensity exercise interspersed with short bursts of high intensity activity. To meet the physical demands of full swing shots and the mental and physical demands of putting and walking the course, it is frequently recommended that golfers undertake golf-specific exercise programs. Biomechanics, motor learning, and motor control research has increased the understanding of the physical requirements of the game, and using this knowledge, exercise programs aimed at improving golf performance have been developed. However, while it is generally accepted that an exercise program can improve a golfer's physical measurements and some golf performance variables, translating the findings from research into clinical practice to optimise an individual golfer's performance remains challenging. This paper discusses how biomechanical and motor control research has informed current practice and discusses how emerging sophisticated tools and research designs may better assist golfers improve their performance.

  20. Current thinking in qualitative research: evidence-based practice, moral philosophies, and political struggle.

    Science.gov (United States)

    Papadimitriou, Christina; Magasi, Susan; Frank, Gelya

    2012-01-01

    In this introduction to the special issue on current thinking in qualitative research and occupational therapy and science, the authors focus on the importance of rigorous qualitative research to inform occupational therapy practice. The authors chosen for this special issue reflect a "second generation of qualitative researchers" who are critical, theoretically sophisticated, methodologically productive, and politically relevant to show that working with disabled clients is political work. Three themes emerged across the articles included in this special issue: (1) recognizing and addressing social justice issues; (2) learning from clients' experiences; and (3) critically reframing occupational therapy's role. These themes can inform occupational therapy practice, research, and education to reflect a more client-centered and politically engaging approach. Copyright 2012, SLACK Incorporated.

  1. An investigation of counter-current flow in porous media with history-dependent modeling

    Science.gov (United States)

    Li, G.; Grader, A. S.; Halleck, P. H.; Karpyn, Z. T.

    2003-04-01

    Counter-current fluid flow occurs in many reservoir processes. It is important to understand and model these processes in order to operate them effectively. Both drainage and imbibition processes exist simultaneously when counter-current flow occurs. It has thus proven difficult to model this type of flow, especially when fluid banks form. Previously, counter-current flow experiments have been done in glass bead packs and the spatial and temporal saturation distributions obtained with X-ray computed tomography (CT). In the current paper, a new saturation-history-dependent approach has been developed to simulate the experiments. Hysteresis in both capillary pressure and relative permeabilities is considered during the process of matching the simulation results to experimental data. Capillary pressure and relative permeabilities are extracted with the aid of a deterministic reservoir simulator. During the history matching process, a family of curves (called scanning curves) is constructed connecting the two branches of the capillary hystersis loop. Each grid block of the sample is assigned a different scanning curve according to its saturation history. Simulation of the experiments reproduced two-dimensional saturation distributions over time with good accuracy. Similar results could not be obtained with traditional simulation using only one capillary pressure curve. History-dependent modeling successfully predicted cross-diameter counter-current flow in a cylindrical geometry. The parameters used in the single capillary pressure method are the average of the parameters used in the history-dependent method. Total effective mobility controls the flow process, being smaller in counter-current flow than in co-current flow. Experiments documented in the literature that exhibited formation of fluid banks were also successfully simulated. We anticipate that application of this method will improve the prediction of full-scale fluid flow processes such as ground water

  2. Research on Land Ecological Condition Investigation and Monitoring Technology

    Science.gov (United States)

    Lv, Chunyan; Guo, Xudong; Chen, Yuqi

    2017-04-01

    The ecological status of land reflects the relationship between land use and environmental factors. At present, land ecological situation in China is worrying. According to the second national land survey data, there are about 149 million acres of arable land located in forests and grasslands area in Northeast and Northwest of China, Within the limits of the highest flood level, at steep slope above 25 degrees; about 50 million acres of arable land has been in heavy pollution; grassland degradation is still serious. Protected natural forests accounted for only 6% of the land area, and forest quality is low. Overall, the ecological problem has been eased, but the local ecological destruction intensified, natural ecosystem in degradation. It is urgent to find out the situation of land ecology in the whole country and key regions as soon as possible. The government attaches great importance to ecological environment investigation and monitoring. Various industries and departments from different angles carry out related work, most of it about a single ecological problem, the lack of a comprehensive surveying and assessment of land ecological status of the region. This paper established the monitoring index system of land ecological condition, including Land use type area and distribution, quality of cultivated land, vegetation status and ecological service, arable land potential and risk, a total of 21 indicators. Based on the second national land use survey data, annual land use change data and high resolution remote sensing data, using the methods of sample monitoring, field investigation and statistical analysis to obtain the information of each index, this paper established the land ecological condition investigation and monitoring technology and method system. It has been improved, through the application to Beijing-Tianjin-Hebei Urban Agglomeration, the northern agro-pastoral ecological fragile zone, and 6 counties (cities).

  3. Person-centred health care: a critical assessment of current and emerging research approaches.

    Science.gov (United States)

    Martin, Carmel M; Félix-Bortolotti, Margot

    2014-12-01

    Person-centred health care is prominent in international health care reforms. A shift to understanding and improving personal care at the point of delivery has generated debates about the nature of the person-centred research agenda. This paper purviews research paradigms that influence current person-centred research approaches and traditions that influence knowledge foundations in the field. It presents a synthesis of the emergent approaches and methodologies and highlights gaps between static academic research and the increasing accessibility of evaluation, informatics and big data from health information systems. Paradigms in health services research range from theoretical to atheoretical, including positivist, interpretive, postmodern and pragmatic. Interpretivist (subjective) and positivist (objectivist) paradigms have been historically polarized. Yet, integrative and pragmatic approaches have emerged. Nevertheless, there is a tendency to reductionism, and to reduce personal experiences to metrics in the positivist paradigm. Integrating personalized information into clinical systems is increasingly driven by the pervasive health information technology, which raises many issues about the asymmetry and uncertainty in the flow of information to support personal health journeys. The flux and uncertainty of knowledge between and within paradigmatic or pragmatic approaches highlights the uncertainty and the 'unorder and disorder' in what is known and what it means. Transdisciplinary, complex adaptive systems theory with multi-ontology sense making provides an overarching framework for making sense of the complex dynamics in research progress. A major challenge to current research paradigms is focus on the individualizing of care and enhancing experiences of persons in health settings. There is an urgent need for person-centred research to address this complex process. A transdisciplinary and complex systems approach provides a sense-making framework. © 2014 John

  4. Investigation of in vitro bone cell adhesion and proliferation on Ti using direct current stimulation

    Energy Technology Data Exchange (ETDEWEB)

    Bodhak, Subhadip; Bose, Susmita [W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164-2920 (United States); Kinsel, William C. [Mechanical Engineering, Washington State University, Tri-Cities, WA (United States); Bandyopadhyay, Amit, E-mail: amitband@wsu.edu [W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164-2920 (United States)

    2012-12-01

    Our objective was to establish an in vitro cell culture protocol to improve bone cell attachment and proliferation on Ti substrate using direct current stimulation. For this purpose, a custom made electrical stimulator was developed and a varying range of direct currents, from 5 to 25 {mu}A, was used to study the current stimulation effect on bone cells cultured on conducting Ti samples in vitro. Cell-material interaction was studied for a maximum of 5 days by culturing with human fetal osteoblast cells (hFOB). The direct current was applied in every 8 h time interval and the duration of electrical stimulation was kept constant at 15 min for all cases. In vitro results showed that direct current stimulation significantly favored bone cell attachment and proliferation in comparison to nonstimulated Ti surface. Immunochemistry and confocal microscopy results confirmed that the cell adhesion was most pronounced on 25 {mu}A direct current stimulated Ti surfaces as hFOB cells expressed higher vinculin protein with increasing amount of direct current. Furthermore, MTT assay results established that cells grew 30% higher in number under 25 {mu}A electrical stimulation as compared to nonstimulated Ti surface after 5 days of culture period. In this work we have successfully established a simple and cost effective in vitro protocol offering easy and rapid analysis of bone cell-material interaction which can be used in promotion of bone cell attachment and growth on Ti substrate using direct current electrical stimulation in an in vitro model. - Highlights: Black-Right-Pointing-Pointer D.C. stimulation was used to enhance in vitro bone cell adhesion and proliferation. Black-Right-Pointing-Pointer Cells cultured on Ti were stimulated by using a custom made electrical stimulator. Black-Right-Pointing-Pointer Optimization was performed by using a varying range of direct currents {approx} 5 to 25 {mu}A. Black-Right-Pointing-Pointer 25 {mu}A stimulation was found most beneficial

  5. The Declaration of Helsinki in relation to medical research: historical and current perspectives.

    Science.gov (United States)

    Shrestha, B M

    2012-09-01

    Medical research aims at improving diagnostic, therapeutic and prophylactic measures and understanding of the aetiology and pathogenesis of diseases in humans, and their application to improve the quality of life and survival. The subjects involved are exposed to hazards inherent to the experiments. In order to protect the human subjects and to maintain high ethical standards, the World Medical Association had adopted the "Declaration of Helsinki" in 1964. The aim of this article is to provide a comprehensive review on the historical and current perspectives on the Declaration of Helsinki in relation to medical research on human subjects.

  6. The current state of the art of quantitative phosphoproteomics and its applications to diabetes research

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Chi Yuet X’avia; Gritsenko, Marina A.; Smith, Richard D.; Qian, Wei-Jun

    2016-03-17

    Protein phosphorylation is a fundamental regulatory mechanism in many cellular processes and aberrant perturbation of phosphorylation has been revealed in various human diseases. Kinases and their cognate inhibitors have been hotspot for drug development. Therefore, the emerging tools, which enable a system-wide quantitative profiling of phosphoproteome, would offer a powerful impetus in unveiling novel signaling pathways, drug targets and/or biomarkers for the disease of interest. In this review, we will highlight recent advances in phosphoproteomics, the current state-of-the-art of the technologies, and the challenges and future perspectives of this research area. Finally, we will underscore some exemplary applications of phosphoproteomics in diabetes research.

  7. The current state of the art of quantitative phosphoproteomics and its applications to diabetes research.

    Science.gov (United States)

    Chan, Chi Yuet X'avia; Gritsenko, Marina A; Smith, Richard D; Qian, Wei-Jun

    2016-01-01

    Protein phosphorylation is a fundamental regulatory mechanism in many cellular processes and aberrant perturbation of phosphorylation has been implicated in various human diseases. Kinases and their cognate inhibitors have been considered as hotspots for drug development. Therefore, the emerging tools, which enable a system-wide quantitative profiling of phosphoproteome, would offer a powerful impetus in unveiling novel signaling pathways, drug targets and/or biomarkers for diseases of interest. This review highlights recent advances in phosphoproteomics, the current state of the art of the technologies and the challenges and future perspectives of this research area. Finally, some exemplary applications of phosphoproteomics in diabetes research are underscored.

  8. Central centrifugal cicatricial alopecia: what has been achieved, current clues for future research.

    Science.gov (United States)

    Ogunleye, Temitayo A; McMichael, Amy; Olsen, Elise A

    2014-04-01

    Central centrifugal cicatricial alopecia is an inflammatory type of central scalp hair loss seen primarily in women of African descent. The prevalence is unknown, but may vary from 2.7% to 5.7% and increases with age. This review outlines the history and current beliefs and identifies clues for future research for this enigmatic condition. Despite that the cause of central centrifugal cicatricial alopecia is unknown, research is ongoing. The role of cytokeratins, androgens, genetics, and various possible sources of chronic inflammation in disease pathogenesis remain to be elucidated.

  9. Current Research and Classroom Practice: Toward More Inclusive Approaches to Literacy Development in Schools

    Directory of Open Access Journals (Sweden)

    David Booth

    2009-07-01

    Full Text Available This paper offers an exploration of current research and related practice in boys’ literacy development, interprets key findings in the literature, and further explores some of the complex dilemmas and debates related to the ‘gender gap’ – i.e., differences between the achievement of boys and girls in this area. In conclusion, the authors suggest that governments, policy-makers, administrators, teachers and parents all need to closely examine and consider available research-based strategies and classroom interventions that can effectively support both boys and girls in their literacy development. 

  10. Mandates, needs, equitable resources, and current research in English language teacher education: The case of Turkey

    Directory of Open Access Journals (Sweden)

    Saban Cepik

    2014-02-01

    Full Text Available Improving the quality of English language teacher education (ELTE programs has become a major point of consideration; however, such programmatic evaluations are markedly rare. This study utilizes both numeric and interpretive qualitative data in a blended research design. The study addresses, vis-à-vis current research in related fields: What is the current situation of the Turkish ELTE programs in terms of curriculum strength and faculty resources? How do the program directors and teacher candidates envision the situation of their programs in terms of curriculum strength and faculty resources? Data included 45 ELTE curricula, interviews with 24 program directors and pre-service teachers, documents, and test scores. Findings revealed several significant associations between school type (public/private and rank (low/high and the number of faculty with expertise in critical areas in the field. Qualitative critical evaluations suggest both perceptual matches and mismatches between program directors and teacher candidates regarding programmatic strengths and weaknesses.

  11. Regeneration of tissues of the oral complex: current clinical trends and research advances.

    Science.gov (United States)

    Nguyen, Thomas T; Mui, Brennan; Mehrabzadeh, Mahsa; Chea, Yannie; Chaudhry, Zoya; Chaudhry, Kamran; Tran, Simon D

    2013-01-01

    Regenerative therapy in oral health care is limited by both the body's natural capacity for regeneration and the materials and methods currently available. Research on various aspects of regenerative therapy, such as tissue engineering and stem cell and gene therapy, has produced promising results. Compelling advances, ranging from the discovery and characterization of stem cell populations in oral tissue to the engineering and transplantation of whole tooth structures, could result in exciting new treatment methods for clinicians in the near future. In this review, we discuss the limitations of natural healing and regeneration of various tissues of the oral complex, including teeth, periodontium and salivary glands, and summarize current treatment methods for tissue damage as well as research advances in oral tissue regeneration.

  12. Investigation of lower hybrid current drive during H-mode in EAST tokamak

    Institute of Scientific and Technical Information of China (English)

    Li Miao-Hui; Liu Fu-Kun; Wang Mao; Xu Han-Dong; Wan Bao-Nian; Ding Bo-Jiang; Kong Er-Hua; Zhang Lei; Zhang Xin-Jun; Qian Jin-Ping; Yan Ning; Han Xiao-Feng; Shan Jia-Fang

    2011-01-01

    H-mode discharges with lower hybrid current drive (LHCD) alone are achieved in EAST divertor plasma over a wide parameter range.These H-mode discharges are characterized by a sudden drop in Dα emission and a spontaneous rise in main plasma density.Good lower hybrid (LH) coupling during H-mode is obtained by putting the plasma close to the antenna and by injecting D2 gas from a pipe near the grill mouse.The analysis of lower hybrid current drive properties shows that the LH deposition profile shifts off axis during H-mode,and current drive (CD) efficiency decreases due to the increase in density.Modeling results of H-mode discharges with a general ray tracing code GENRAY are reported.

  13. Where Is Current Research on Blockchain Technology?—A Systematic Review

    Science.gov (United States)

    Yli-Huumo, Jesse; Ko, Deokyoon; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers. PMID:27695049

  14. Where Is Current Research on Blockchain Technology?-A Systematic Review.

    Science.gov (United States)

    Yli-Huumo, Jesse; Ko, Deokyoon; Choi, Sujin; Park, Sooyong; Smolander, Kari

    2016-01-01

    Blockchain is a decentralized transaction and data management technology developed first for Bitcoin cryptocurrency. The interest in Blockchain technology has been increasing since the idea was coined in 2008. The reason for the interest in Blockchain is its central attributes that provide security, anonymity and data integrity without any third party organization in control of the transactions, and therefore it creates interesting research areas, especially from the perspective of technical challenges and limitations. In this research, we have conducted a systematic mapping study with the goal of collecting all relevant research on Blockchain technology. Our objective is to understand the current research topics, challenges and future directions regarding Blockchain technology from the technical perspective. We have extracted 41 primary papers from scientific databases. The results show that focus in over 80% of the papers is on Bitcoin system and less than 20% deals with other Blockchain applications including e.g. smart contracts and licensing. The majority of research is focusing on revealing and improving limitations of Blockchain from privacy and security perspectives, but many of the proposed solutions lack concrete evaluation on their effectiveness. Many other Blockchain scalability related challenges including throughput and latency have been left unstudied. On the basis of this study, recommendations on future research directions are provided for researchers.

  15. Potential of nanotechnology as a delivery platform against tuberculosis: current research review.

    Science.gov (United States)

    Choudhary, S; Kusum Devi, V

    2015-03-28

    This review focusses on the current ongoing research in the field of tuberculosis comprising the resistant strains. It specifies a proper data analysis with results in concise form from areas gripping in: diagnostic nanotechnology, vaccine nanotechnology and the prime field of interest i.e., therapeutic nanotechnology. Primarily, therapeutic area recollects the research findings from advanced drug delivery (primary era) to the targeted drug delivery (modern era). The vaccine-based area derives the immune-specific targeting with enhanced emphasis on vaccine extraction and preparation of nanoparticles. Finally, the diagnostic area signifies the imaging techniques that may be employed in the diagnosis of TB. Not only that, there are some researches that emphasized on finding the comparable diagnostic differences between normal and resistant strains. With the advent of carbon nanotubes, metallic NPs, a newer hope has emerged out in diagnostic research, which may extend to therapeutic research applications too. Modifications of natural polymers, least or no use of organic solvents, size controlled NPs, optimized methodology, etc., are fields that need more effort to bypass toxicity. If above desired possibilities get the priority during research, it may lead to shift in the timeline towards much more oriented research. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Investigation of leakage current and breakdown voltage in irradiated double-sided 3D silicon sensors

    Science.gov (United States)

    Dalla Betta, G.-F.; Ayllon, N.; Boscardin, M.; Hoeferkamp, M.; Mattiazzo, S.; McDuff, H.; Mendicino, R.; Povoli, M.; Seidel, S.; Sultan, D. M. S.; Zorzi, N.

    2016-09-01

    We report on an experimental study aimed at gaining deeper insight into the leakage current and breakdown voltage of irradiated double-sided 3D silicon sensors from FBK, so as to improve both the design and the fabrication technology for use at future hadron colliders such as the High Luminosity LHC. Several 3D diode samples of different technologies and layout are considered, as well as several irradiations with different particle types. While the leakage current follows the expected linear trend with radiation fluence, the breakdown voltage is found to depend on both the bulk damage and the surface damage, and its values can vary significantly with sensor geometry and process details.

  17. Investigation of cathodic current collection in lithium/manganese dioxide cells by electrochemical impedance spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Merritt, D.R.; Schmidt, C.L. [Medtronic, Inc., Minneapolis, MN (United States)

    1994-12-31

    Contact impedance between pressed composite manganese dioxide cathodes and current collectors has been shown to play an important role in the overall impedance of primary Li/MnO{sub 2} cells. Specifically, this impedance is manifested by an arc in the complex-plane impedance plot, representative of a parallel resistive/capacitive combination, This paper presents the results of a systematic series of experiments designed to better define the relationship between cathodic current collector configuration and cell impedance. A refined equivalent circuit model of the Li/MnO{sub 2} cell is also presented.

  18. Nuclear microscopy in medical research. Investigations into degenerative diseases

    Energy Technology Data Exchange (ETDEWEB)

    Makjanic, J.; Thong, P.; Watt, F. [National University of Singapore (Singapore). Dept. of Physics

    1997-03-01

    The high energy (1-4MeV) focused ion beam (nuclear microbeam) has found uses in many scientific disciplines through a wide variety of ion beam based techniques. Of the many techniques available, the powerful combination of Particle Induced X-Ray Emission (PIXE), Rutherford Backscattering Spectrometry (RBS), and Scanning Transmission Ion Microscopy (STIM) is proving to be extremely useful, particularly in the characterisation and elemental analysis of thin specimens. In this paper we briefly review these ion beam techniques, as well as the hardware required for their application. Finally, we describe the application of the PIXE, RBS and STIM techniques in conjunction with a scanning focused 2MeV proton microbeam (nuclear microscopy). The examples chosen to illustrate the potential of nuclear microscopy are recent investigations into the degenerative diseases atherosclerosis (coronary heart disease), Parkinson`s disease and Alzheimer`s disease. (author)

  19. MicroRNAs as Biomarkers for Psychiatric Conditions: A Review of Current Research

    Science.gov (United States)

    Hussain, Mariyah; Sreeram, Venkatesh

    2017-01-01

    Neural-derived exosomes can be used as diagnostic markers to screen for various psychiatric conditions. These intravenously injected exosomes carry the potential to cross the blood brain barrier and deliver miRNA molecules specifically to neurons, microglia, and oligodendrocytes in the brain, resulting in specific gene knockdown. Here the authors review and discuss the current research on microRNA molecules and the therapeutic roles they may potentially play in treating depression, bipolar disorder, and schizophrenia.

  20. Ways of Thinking Globalisation--Insights into a Currently Running Investigation of Students' Ideas of Globalisation

    Science.gov (United States)

    Fischer, Sebastian; Fischer, Florian; Kleinschmidt, Malte; Lange, Dirk

    2014-01-01

    The investigation is about which ideas ninth form students at grammar schools and secondary modern schools have about globalisation. It shall be investigated if the perception of and judgement on globalisation-connected contexts happens along social structure-specific patterns. At first, by way of a questionnaire, the field of ideas is supposed to…

  1. Aacap 2001 Research Forum: Challenges and Recommendations regarding Recruitment and Retention of Participants in Research Investigations

    Science.gov (United States)

    Hinshaw, Stephen P.; Hoagwood, Kimberly; Jensen, Peter S.; Kratochvil, Christopher; Bickman, Leonard; Clarke, Greg; Abikoff, Howard B.; Atkins, Marc; Vitiello, Benedetto

    2004-01-01

    Objective: Clinical research depends on the participation of representative samples. At the 2001 Annual Meeting of the American Academy of Child and Adolescent Psychiatry, the Workgroup on Research conducted a research forum with the purpose of improving recruitment and retention of children and adolescents in research protocols. Method: An…

  2. Investigation of sounding rocket observations of field-aligned currents and electron temperature

    Science.gov (United States)

    Cohen, I. J.; Lessard, M.; Zettergren, M. D.; Moen, J.; Lynch, K. A.; Heavisides, J. M.

    2014-12-01

    Strangeway et al. [2005] and other authors have concluded that the establishment of the ambipolar field by the deposition of energy from soft electron precipitation is a significant driver of type-2 ion upflows. Likewise, Clemmons et al. [2008] and Zhang et al. [2012] proposed processes by which soft electron precipitation may play a role in heating neutrals and contribute to neutral upwelling. In both situations the thermal ionospheric electron population plays a crucial role in both generation of the ambipolar field and in collisional energy exchange with the atmosphere through a variety of processes. In this study we examine the dynamics of the electron population, specifically the temperature, in a slightly different context - focusing on the auroral downward current region (DCR). In many cases auroral DCRs may be depleted of plasma, which sets up interesting conditions involving thermoelectric heat fluxes (which flow upward - in the opposite direction from the current), adiabatic expansion due to the high (upward) speed of the electrons carrying the downward current, heat exchange from ions which have elevated temperatures due to frictional heating, and direct frictional heating of the electrons. A detailed understanding of the electron temperature in auroral DCRs is necessary to make quantitative statements about recombination, upflow, cavitation and a host of other processes relevant to ion outflow. In this study, we compare in situ rocket observations of electron temperature, density, and current densities with predictions from the Zettergren and Semeter [2012] model in an attempt to better understand the dynamics and relationships between these parameters in DCRs.

  3. Investigation of optical currents in coherent and partially coherent vector fields

    DEFF Research Database (Denmark)

    Angelsky, O. V.; Gorsky, M. P.; Maksimyak, P. P.

    2011-01-01

    in the arrangements of two-wave and four-wave superposition on the characteris-tics of the microparticle’s motion has been analyzed. The prospects of stud-ying temporal coherence using the proposed approach are made. For the first time, the possibility of diagnostics of optical currents in liquids caused...

  4. Current-voltage behaviour of bipolar membranes in concentrated salt solutions investigated with chronopotentiometry

    NARCIS (Netherlands)

    Wilhelm, F.G.; Vegt, van der N.F.A.; Strathmann, H.; Wessling, M.

    2002-01-01

    Chronopotentiometry is used as a tool to obtain detailed information on the transport behaviour of the bipolar membrane BP-1 in solutions of high sodium chloride concentration above the limiting current density. We discuss critically the interpretation of the observed transition times. The occurrenc

  5. Energy and materials conservation: applying pioneering research and techniques to current non-energy materials conservation issues.

    Science.gov (United States)

    Hannon, Bruce

    2013-03-13

    The research of the Energy Research Group (ERG) at the University of Illinois at Urbana-Champaign through the 1970s and early 1980s has recurring bouts of popularity. That research traced the flow of various energy types from nature to the final product or service, using modified economic input-output analysis. That information allowed for a comparison of alternative uses of products and services that delivered the same demand. The goal of the study was to identify the energy-conserving potential of the alternatives. Interest in that research has risen and fallen with the price of energy through three cycles now, with the current interest also encompassing materials conservation. Although the specific numerical results of this work are dated, the process by which the analysis was conducted creates, at least, a suggestion for future analysis in the arena of materials research. A review of the ERG history, including techniques pioneered for investigating the potential for energy conservation and some of the ancillary lessons learned along the way, may be of some use to those working on issues of materials conservation today. In the coming years, the most relevant research will include assessment of the socio-economic-ecological impact of technological materials conservation policies.

  6. Investigation and Development of Control Laws for the NASA Langley Research Center Cockpit Motion Facility

    Science.gov (United States)

    Coon, Craig R.; Cardullo, Frank M.; Zaychik, Kirill B.

    2014-01-01

    The ability to develop highly advanced simulators is a critical need that has the ability to significantly impact the aerospace industry. The aerospace industry is advancing at an ever increasing pace and flight simulators must match this development with ever increasing urgency. In order to address both current problems and potential advancements with flight simulator techniques, several aspects of current control law technology of the National Aeronautics and Space Administration (NASA) Langley Research Center's Cockpit Motion Facility (CMF) motion base simulator were examined. Preliminary investigation of linear models based upon hardware data were examined to ensure that the most accurate models are used. This research identified both system improvements in the bandwidth and more reliable linear models. Advancements in the compensator design were developed and verified through multiple techniques. The position error rate feedback, the acceleration feedback and the force feedback were all analyzed in the heave direction using the nonlinear model of the hardware. Improvements were made using the position error rate feedback technique. The acceleration feedback compensator also provided noteworthy improvement, while attempts at implementing a force feedback compensator proved unsuccessful.

  7. Medical Big Data for Research Use: Current Status and Related Issues.

    Science.gov (United States)

    Ishikawa, Koichi Benjamin

    2016-09-01

    Advances in the computerization of information and development of technology have mitigated restrictions on handling of a large amount of information. This has resulted in growth of expectations for the use of large-scale databases, or so-called "big data." This is also the case in the field of healthcare. Projects that involve building of the national receipt database (NDB) of medical fee bill (receipt) information and special health check-up information based on the Act on Assurance of Medical Care for Elderly People and the development of medical information databases have been pursued by the national government, and considerable attention has also been focused on researches conducted through the secondary uses of publicly collected data. Aside from these trends, there are numerous projects which collect diagnosis procedure combination (DPC) data to build large-scale databases for research purposes. Following to the ethics guidelines for epidemiologic studies, they collect and analyze anonymized DPC data from cooperating institutions. This communication concentrates on the use of DPC data, and outlines the scale of data currently available for research use. Examples on the use of DPC data will be shown for analysis on the current status of clinical practice from the microscopic perspective and macroscopic analysis of community medical care provision. Additionally, potential for extending studies to long-term outcomes research, limitations and issues related to the use of medical big data will also be discussed.

  8. Review of current interest and research in water hyacinth-based wastewater treatment

    Science.gov (United States)

    Markarian, R. K.; Balon, J. E.; Robinson, A. C.

    1977-01-01

    The status of activity in the user community for water hyacinth-based wastewater treatment was evaluated. The principal technique used was that of interviewing people who either (1) were known to be engaged in hyacinth research or development or (2) had made inquiry to NASA about hyacinth systems. About 40 non-research organizations and a similar number of research organizations were contacted. As a result of the interviews and a review of the relevant literature, it was concluded that hyacinth systems have the potential for providing a lower cost way for small cities to meet increasingly stringent effluent requirements. A limited amount of full-scale demonstration of hyacinth systems has been carried out during the past two years, but the yield of design data has been small. Several organizations are currently planning construction of experimental full-scale hyacinth-based wastewater treatment systems during 1977-1978.

  9. Attachment among older adults: current issues and directions for future research.

    Science.gov (United States)

    Bradley, J M; Cafferty, T P

    2001-09-01

    Although John Bowlby conceptualized attachment theory as applicable across the life span, researchers have been relatively slow to examine attachment phenomena specifically among older adults. The present article reviews the extant research applying attachment theory to older populations; preliminary findings suggest that attachment issues hold particular relevance for older adults, given the increased potential for separation, loss and vulnerability associated with aging. Although many of the studies reviewed are somewhat limited methodologically, the overall pattern of results suggests that attachment patterns are associated with a variety of outcomes in later life (such as adaptation to chronic illness and caregiver burden among family members, reactions to the death of a loved one, and general well-being) in a theoretically consistent manner. The implications of and questions raised by current findings are reviewed, and directions for future research are discussed.

  10. Unmanned aircraft systems in wildlife research: Current and future applications of a transformative technology

    Science.gov (United States)

    Christie, Katherine S.; Gilbert, Sophie L.; Brown, Casey L.; Hatfield, Michael; Hanson, Leanne

    2016-01-01

    Unmanned aircraft systems (UAS) – also called unmanned aerial vehicles (UAVs) or drones – are an emerging tool that may provide a safer, more cost-effective, and quieter alternative to traditional research methods. We review examples where UAS have been used to document wildlife abundance, behavior, and habitat, and illustrate the strengths and weaknesses of this technology with two case studies. We summarize research on behavioral responses of wildlife to UAS, and discuss the need to understand how recreational and commercial applications of this technology could disturb certain species. Currently, the widespread implementation of UAS by scientists is limited by flight range, regulatory frameworks, and a lack of validation. UAS are most effective when used to examine smaller areas close to their launch sites, whereas manned aircraft are recommended for surveying greater distances. The growing demand for UAS in research and industry is driving rapid regulatory and technological progress, which in turn will make them more accessible and effective as analytical tools.

  11. Qualitative ergonomics/human factors research in health care: Current state and future directions.

    Science.gov (United States)

    Valdez, Rupa Sheth; McGuire, Kerry Margaret; Rivera, A Joy

    2017-07-01

    The objective of this systematic review was to understand the current state of Ergonomics/Human Factors (E/HF) qualitative research in health care and to draw implications for future efforts. This systematic review identified 98 qualitative research papers published between January 2005 and August 2015 in the seven journals endorsed by the International Ergonomics Association with an impact factor over 1.0. The majority of the studies were conducted in hospitals and outpatient clinics, were focused on the work of formal health care professionals, and were classified as cognitive or organizational ergonomics. Interviews, focus groups, and observations were the most prevalent forms of data collection. Triangulation and data archiving were the dominant approaches to ensuring rigor. Few studies employed a formal approach to qualitative inquiry. Significant opportunities remain to enhance the use of qualitative research to advance systems thinking within health care. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. National and International Migration:Reflections on Literature and Some Current Research1

    Institute of Scientific and Technical Information of China (English)

    Nicholas Tapp(Wang Fuwen)

    2013-01-01

    This article gives a review on literature and some current research relevant to na-tional and international migration , and examines the connections between such research in a na-tional context , and the research on international migration .The approaches to migration in migra-tion studies are very complex , and the author suggested that we need to pay attention to all three approaches contrasted by Solinger:the one based on rational calculation , the one based on stress-ing the historico-structural conditions and the one based on social networking analysis .The au-thor also stresses the importance of a network approach taken from the sociology of John Urry in the studies of both national and international migration , and the need to see movement as prima-ry, and productive of place , as much recent anthropological literature has stressed .

  13. Pharmacotherapy for the core symptoms in autistic disorder: current status of the research.

    Science.gov (United States)

    Farmer, Cristan; Thurm, Audrey; Grant, Paul

    2013-03-01

    The current review covers extant literature on pharmacotherapy for core symptoms of autism. The core symptoms of autism include impairments in social interaction and communication, as well as the presence of restricted and repetitive behaviors. There are no known efficacious treatments for the core social symptoms, although effects on repetitive behaviors are indicated with some data. While studies of fenfluramine, secretin, opiates, and mood stabilizers generally find no effect, mixed results suggest more research is needed on antidepressants and atypical antipsychotics. Newer lines of research, including cholinergic and glutamatergic agents and oxytocin, will be of considerable interest in the future. However, research on the treatment of core symptoms is plagued by limitations in study design, statistical power, and other issues inherent to the study of treatments for autism (e.g., heterogeneity of the disorder) that continue to prevent the elucidation of efficacious treatments.

  14. Constructed wetlands, 1991-2011: a review of research development, current trends, and future directions.

    Science.gov (United States)

    Zhi, Wei; Ji, Guodong

    2012-12-15

    This study explores a bibliometric approach to quantitatively evaluate global scientific constructed wetlands research, and statistically assess current trends, and future directions using the Science Citation Index Expanded (SCI-EXPANDED) database from 1991 to 2011. Articles referencing constructed wetlands were analyzed by accessing the following: publication language, output characteristics, publication performance by country and institution, author keywords, title words, and KeyWords Plus. Synthetically analyzing three keyword types, we concluded that the dominant constructed wetlands research hotspots from 1991 to 2011 included water, nutrients, plants, and flow. These four hotspots remained the most dominant research areas throughout our study period, and are predicted to remain the top research emphases in the near future. "Soil" also exhibited a notable increase since 2005, and is likely to become another notable area of research interest in the future. "Phytoremediation" and "horizontal" were not identified in 1991-1995, but exhibited marked increases from 136th (0.5%) and 169th (0.7%) in 1996-2000, to 9th (3.8%) and 11th (4.3%) in 2006-2011, respectively. Therefore, given the heightened attention during the last 15 years, these topics are likely to become a primary research focus in upcoming years.

  15. GEOS-3 ocean current investigation using radar altimeter profiling. [Gulf Stream surface topography

    Science.gov (United States)

    Leitao, C. D.; Huang, N. E.; Parra, C. G.

    1978-01-01

    Both quasi-stationary and dynamic departures from the marine geoid were successfully detected using altitude measurements from the GEOS-3 radar altimeter. The quasi-stationary departures are observed either as elevation changes in single pass profiles across the Gulf Stream or at the crowding of contour lines at the western and northern areas of topographic maps generated using altimeter data spanning one month or longer. Dynamic features such as current meandering and spawned eddies can be monitored by comparing monthly mean maps. Comparison of altimeter inferred eddies with IR detected thermal rings indicates agreement of the two techniques. Estimates of current velocity are made using derived slope estimates in conjunction with the geostrophic equation.

  16. A computational investigation of cardiac caveolae as a source of persistent sodium current

    Directory of Open Access Journals (Sweden)

    Ian M. Besse

    2011-11-01

    Full Text Available Recent studies of cholesterol-rich membrane microdomains, called caveolae, reveal that caveolae are reservoirs of recruitable sodium ion channels. Caveolar channels constitute a substantial and previously unrecognized source of sodium current in cardiac cells. In this paper we model for the first time caveolar sodium currents and their contributions to cardiac action potential morphology. We show that the beta-agonist-induced opening of caveolae may have substantial impacts on peak overshoot, maximum upstroke velocity, and ultimately conduction velocity. Additionally, we show that prolonged action potentials and the formation of potentially arrhythmogenic afterdepolarizations, can arise if caveolae open intermittently throughout the action potential. Our simulations suggest that there may exist routes to delayed repolarization, and the arrhythmias associated with such delays, that are independent of channelopathies.

  17. Investigation of drain current transient behavior in SLS TFTs with the DLTS technique

    Energy Technology Data Exchange (ETDEWEB)

    Exarchos, M A [National and Kapodistrian University of Athens, Physics Department, Solid State Physics Section, Athens 15784 (Greece); Papaioannou, G J [National and Kapodistrian University of Athens, Physics Department, Solid State Physics Section, Athens 15784 (Greece); Kouvatsos, D N [N.C.S.R. Demokritos, Institute of Microelecronics, Athens 15310 (Greece); Voutsas, A T [L.C.D. Process Technology Laboratory, SHARP Labs of America, Inc., Washington 98607 (United States)

    2005-01-01

    In this work, the study of drain current overshoot transients of thin film transistors (TFTs) fabricated by excimer laser sequential lateral solidification (ELA SLS) process is presented. Drain current transient behavior, is ascribed to carrier capture/emission processes within the transistors' Si body, and represents complex mechanisms differently responding at dark and under illumination conditions. Additionally, the thickness of the Si body film, which is an important parameter for the material structure evaluation, ranged from 30 nm to 100 nm. The results were stemmed by deep level transient spectroscopy (DLTS) technique and measurements were conducted within the temperature interval of 200 K to 400 K. The impact of illumination, contributes mainly at lower temperatures through electron-hole generation processes, compensating though carrier freeze-out phenomena.

  18. Investigation of drain current transient behavior in SLS TFTs with the DLTS technique

    Science.gov (United States)

    Exarchos, M. A.; Papaioannou, G. J.; Kouvatsos, D. N.; Voutsas, A. T.

    2005-01-01

    In this work, the study of drain current overshoot transients of thin film transistors (TFTs) fabricated by excimer laser sequential lateral solidification (ELA SLS) process is presented. Drain current transient behavior, is ascribed to carrier capture/emission processes within the transistors' Si body, and represents complex mechanisms differently responding at dark and under illumination conditions. Additionally, the thickness of the Si body film, which is an important parameter for the material structure evaluation, ranged from 30 nm to 100 nm. The results were stemmed by deep level transient spectroscopy (DLTS) technique and measurements were conducted within the temperature interval of 200 K to 400 K. The impact of illumination, contributes mainly at lower temperatures through electron-hole generation processes, compensating though carrier freeze-out phenomena.

  19. Investigations on the performances of the electrical generator of a rim-driven marine current turbine”

    OpenAIRE

    2008-01-01

    In this paper, the electrical generator of a rim-driven horizontal-axis current turbine is modeled in detail. Its main characteristics and performances are evaluated (efficiency, mass, cost, etc). This generator is of permanent magnet direct-driven synchronous type and is connected to a variable speed power electronics drive. It is then compared to a more traditional technology (a pod generator) in terms of mass and cost for a common set of specification. In addition, due to the specific geom...

  20. Investigations on the electrical current-voltage response in protein light receptors

    CERN Document Server

    Alfinito, E; Reggiani, L

    2014-01-01

    We report a theoretical/computational approach for modeling the current-voltage characteristics of sensing proteins. The modeling is applied to a couple of transmembrane proteins, bacteriorhodopsin and proteorhodopsin, sensitive to visible light and promising biomaterials for the development of a new generation of photo-transducers. The agreement between theory and experiments sheds new light on the microscopic interpretation of charge transfer in proteins and biological materials in general.

  1. Experimental investigation of quasiperiodic-chaotic-quasiperiodic-chaotic transition in a direct current magnetron sputtering plasma

    Energy Technology Data Exchange (ETDEWEB)

    Sabavath, Gopi Kishan; Banerjee, I.; Mahapatra, S. K., E-mail: skmahapatra@bitmesra.ac.in [Plasma Laboratory, Department of Physics, Birla Institute of Technology-Mesra, Ranchi 835215 (India); Shaw, Pankaj Kumar; Sekar Iyengar, A. N. [Plasma Physics Division, Saha Institute of Nuclear Physics, 1/AF, Bidhannagar, Kolkata 700064 (India)

    2015-08-15

    Floating potential fluctuations from a direct current magnetron sputtering plasma have been analysed using time series analysis techniques like phase space plots, power spectra, frequency bifurcation plot, etc. The system exhibits quasiperiodic-chaotic-quasiperiodic-chaotic transitions as the discharge voltage was increased. The transitions of the fluctuations, quantified using the largest Lyapunov exponent, have been corroborated by Hurst exponent and the Shannon entropy. The Shannon entropy is high for quasiperiodic and low for chaotic oscillations.

  2. Investigating and stimulating primary teachers’ attitudes towards science: Summary of a large-scale research project

    NARCIS (Netherlands)

    Walma van der Molen, Julie Henriëtte; van Aalderen-Smeets, Sandra

    2013-01-01

    Attention to the attitudes of primary teachers towards science is of fundamental importance to research on primary science education. The current article describes a large-scale research project that aims to overcome three main shortcomings in attitude research, i.e. lack of a strong theoretical

  3. Investigating and Stimulating Primary Teachers' Attitudes Towards Science: Summary of a Large-Scale Research Project

    Science.gov (United States)

    Walma van der Molen, Juliette; van Aalderen-Smeets, Sandra

    2013-01-01

    Attention to the attitudes of primary teachers towards science is of fundamental importance to research on primary science education. The current article describes a large-scale research project that aims to overcome three main shortcomings in attitude research, i.e. lack of a strong theoretical concept of attitude, methodological flaws in…

  4. Investigating and stimulating primary teachers’ attitudes towards science: Summary of a large-scale research project

    NARCIS (Netherlands)

    Walma van der Molen, Juliëtte; Aalderen-Smeets, van Sandra Iris

    2013-01-01

    Attention to the attitudes of primary teachers towards science is of fundamental importance to research on primary science education. The current article describes a large-scale research project that aims to overcome three main shortcomings in attitude research, i.e. lack of a strong theoretical con

  5. Investigation of data retention under current bias for phase change memory

    Science.gov (United States)

    Lu, Yao-Yao; Cai, Dao-Lin; Chen, Yi-Feng; Wang, Yue-Qing; Wei, Hong-Yang; Huo, Ru-Ru; Song, Zhi-Tang

    2016-10-01

    With Phase-change memory (PCM), information can be stored as different resistance states even when not powered. In order to accurately characterize the reliability of PCM devices, data retention has to be tested carefully. In this paper, a new test method is applied to measure the data retention of T-shaped PCM devices. This method makes it possible to accelerate crystallization in the amorphous area by using current bias. The new method works based on the field-induced crystallization theory, and could be able to gather fast and detailed information about high-resistance state's failure process, and at the same time, it could avoid issues related to high temperature. Experimental data for T-shaped PCM devices based on Ge2Sb2Te5 are presented and analyzed. An exponential trend-line of failure time t versus reciprocal bias current 1/I shows only negligible deviation of the measured data points, enabling the extrapolation of the retention behavior for ten-year lifetime. A maximum disturb current value of 5.08 μA is extracted to guarantee the ten years data retention requirement for PCM applications.

  6. Current trends and new challenges of databases and web applications for systems driven biological research

    Directory of Open Access Journals (Sweden)

    Pradeep Kumar eSreenivasaiah

    2010-12-01

    Full Text Available Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and web application. Several solutions have been proposed to meet the expectations and novel methods have been developed to address the persisting problems of data integration. It is important for researchers to understand different technologies and approaches. Having familiarized with the pros and cons of the existing technologies, researchers can exploit its capabilities to the maximum potential for integrating data. In this review we discuss the architecture, design and key technologies underlying some of the prominent databases (DBs and web applications. We will mention their roles in integration of biological data and investigate some of the emerging design concepts and computational technologies that are likely to have a key role in the future of systems driven biomedical research.

  7. Deliberate Microbial Infection Research Reveals Limitations to Current Safety Protections of Healthy Human Subjects.

    Science.gov (United States)

    Evers, David L; Fowler, Carol B; Mason, Jeffrey T; Mimnall, Rebecca K

    2015-08-01

    Here we identify approximately 40,000 healthy human volunteers who were intentionally exposed to infectious pathogens in clinical research studies dating from late World War II to the early 2000s. Microbial challenge experiments continue today under contemporary human subject research requirements. In fact, we estimated 4,000 additional volunteers who were experimentally infected between 2010 and the present day. We examine the risks and benefits of these experiments and present areas for improvement in protections of participants with respect to safety. These are the absence of maximum limits to risk and the potential for institutional review boards to include questionable benefits to subjects and society when weighing the risks and benefits of research protocols. The lack of a duty of medical care by physician-investigators to research subjects is likewise of concern. The transparency of microbial challenge experiments and the safety concerns raised in this work may stimulate further dialogue on the risks to participants of human experimentation.

  8. Current and future molecular approaches to investigate the white pine blister rust pathosystem

    Science.gov (United States)

    B. A. Richardson; A. K. M. Ekramoddoulah; J.-J. Liu; M.-S. Kim; N. B. Klopfenstein

    2010-01-01

    Molecular genetics is proving to be especially useful for addressing a wide variety of research and management questions on the white pine blister rust pathosystem. White pine blister rust, caused by Cronartium ribicola, is an ideal model for studying biogeography, genetics, and evolution because: (1) it involves an introduced pathogen; (2) it includes multiple primary...

  9. CURRENT APPLIED INVESTIGATIONS OF THE DEPARTMENT OF HIGHER MATHEMATICS OF MGSU

    Directory of Open Access Journals (Sweden)

    Bobyleva Tat’yana Nikolaevna

    2015-12-01

    Full Text Available The article presents an overview of some research works done by the academic staff of the Department in the field of differential equations, solid mechanics, probability theory and mathematical statistics, theory of functions of real and complex variable, functional analysis, topology, the theory of polymer composites having theoretical and practical interest, which leads to wide possibilities of application of these researches for formulation and solution of model problems of construction, technology and economics. In particular, we considered the problem of planar non-rotational fluid flow with a free boundary, discrete kinetic model of rarefied gas, the Burgers-Huxley equation of advection-diffusion fractional order. We studied the stress concentrators due to the geometry of the boundary and coupling elements made of materials with different physical properties, stress relaxation in concrete, free vibrations of isotropic hollow balls. The issues of loaded systems’ research arise frequently in practice in the problems with lumped loads. Extremum problems were considered, in particular, in the loaded space of Jacobi, extremum problems for analytic functions of some classes, the use of the duality of linear spaces applied to extremum problems of complex analysis. The researches on methods of teaching mathematics in technical universities were performed.

  10. Investigation of iron current measurement to detect combustion quality; Ion denryu ni yoru nensho jotai kenshutsu no kento

    Energy Technology Data Exchange (ETDEWEB)

    Nakata, K.; Mogi, K. [Toyota Motor Corp., Aichi (Japan)

    1997-10-01

    The possibility and problems were investigated in detecting the combustion quality by means of ion current measured at the spark plug. The ion current has two peaks during one combustion stroke; first peak is generated by flame around the spark plug just after ignition and second one appears with the rise in temperature of burned gases. As the result of investigations, it was confirmed that the first ion peak might be useful to forecast the combustion quality, but it would be hard to practice owing to the spark duration. And the second peak offered the information of combustion chamber pressure. 4 refs., 12 figs., 1 tab.

  11. A descriptive investigation of the impact of student research projects arising from elective research courses.

    Science.gov (United States)

    Harirforoosh, Sam; Stewart, David W

    2016-01-27

    Pharmacy academicians have noted the need to develop research skills in student pharmacists. At the Gatton College of Pharmacy, significant focus has been placed on the development of research skills through offering elective research courses. In order to evaluate the impact of participation in the research elective(s), we analyzed college records and surveyed faculty members with regard to the number of poster/podium presentations, published peer-reviewed manuscripts, and funded projects. Student enrollment in the research elective sequence has increased over time and has resulted in 81 poster presentations, 14 podium presentations, and 15 peer-reviewed publications. Implementation of a research elective sequence and fostering of a research culture amongst the faculty and students has resulted in increased student engagement in research and related scholarly activities.

  12. Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System

    Science.gov (United States)

    Farrelly, L.A.; Dill, B.D.; Molina, H.; Birtwistle, M.R.; Maze, I.

    2016-01-01

    Characterizing the dynamic behavior of nucleosomes in the central nervous system is vital to our understanding of brain-specific chromatin-templated processes and their roles in transcriptional plasticity. Histone turnover—the complete loss of old, and replacement by new, nucleosomal histones—is one such phenomenon that has recently been shown to be critical for cell-type-specific transcription in brain, synaptic plasticity, and cognition. Such revelations that histones, long believed to static proteins in postmitotic cells, are highly dynamic in neurons were only possible owing to significant advances in analytical chemistry-based techniques, which now provide a platform for investigations of histone dynamics in both healthy and diseased tissues. Here, we discuss both past and present proteomic methods (eg, mass spectrometry, human “bomb pulse labeling”) for investigating histone turnover in brain with the hope that such information may stimulate future investigations of both adaptive and aberrant forms of “neuroepigenetic” plasticity. PMID:27423867

  13. An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling.

    Science.gov (United States)

    Prakash, Y S; Halayko, Andrew J; Gosens, Reinoud; Panettieri, Reynold A; Camoretti-Mercado, Blanca; Penn, Raymond B

    2017-01-15

    Airway remodeling (AR) is a prominent feature of asthma and other obstructive lung diseases that is minimally affected by current treatments. The goals of this Official American Thoracic Society (ATS) Research Statement are to discuss the scientific, technological, economic, and regulatory issues that deter progress of AR research and development of therapeutics targeting AR and to propose approaches and solutions to these specific problems. This Statement is not intended to provide clinical practice recommendations on any disease in which AR is observed and/or plays a role. An international multidisciplinary group from within academia, industry, and the National Institutes of Health, with expertise in multimodal approaches to the study of airway structure and function, pulmonary research and clinical practice in obstructive lung disease, and drug discovery platforms was invited to participate in one internet-based and one face-to-face meeting to address the above-stated goals. Although the majority of the analysis related to AR was in asthma, AR in other diseases was also discussed and considered in the recommendations. A literature search of PubMed was performed to support conclusions. The search was not a systematic review of the evidence. Multiple conceptual, logistical, economic, and regulatory deterrents were identified that limit the performance of AR research and impede accelerated, intensive development of AR-focused therapeutics. Complementary solutions that leverage expertise of academia and industry were proposed to address them. To date, numerous factors related to the intrinsic difficulty in performing AR research, and economic forces that are disincentives for the pursuit of AR treatments, have thwarted the ability to understand AR pathology and mechanisms and to address it clinically. This ATS Research Statement identifies potential solutions for each of these factors and emphasizes the importance of educating the global research community as to the

  14. 江西省医疗卫生机构BSL-2实验室现状调查与管理对策研究%Investigation and countermeasure research on the current status of BSL-2 laboratory of medical and public health departments in Jiangxi province

    Institute of Scientific and Technical Information of China (English)

    邹明霞; 于子颖; 叶颖; 张静; 肖坚孝

    2013-01-01

    目的 了解江西省医疗卫生机构BSL-2实验室生物安全管理现状,为卫生行政部门加强和规范实验室生物安全管理提供对策依据.方法 以现场评估和问卷调查相结合的方式,2010~2011年对江西省各类医疗卫生机构共计55家单位的BSL-2实验室进行生物安全现场检查.结果 江西省医疗卫生机构BSL-2实验室已逐步建立生物安全管理体系,但有些单位存在实验室备案不全,菌毒种运输管理、生物安全管理制度、实验室设施设备、生物安全措施薄弱的现象.结论 各类医疗卫生机构生物安全管理存在不同差距,有待政府行政部门应加强监管,进一步完善医疗卫生机构的生物安全管理.%OBJECTIVE To find out medical and public health departments' situation of BSL-2 laboratory biosafety management in Jiangxi province so as to offer countermeasures to health administrative departments.METHODS 55 medical and public health departments' BSL-2 laboratory biosafety managements were investigated in 2010-2011 by field assessments and questionnaire surveys.RESULTS BSL-2 laboratory of Jiangxi province had established biosafety management system gradually,some laboratories' records were incomplete,the management of poisonous species of bacteria's transportation,bio-safety system,laboratory facilities and bio-security measures still had some weak points.CONCLUSION There are differences between medical and public health departments in biological safety management.Supervision should be strengthened and effective measures should be taken by executive branch of government.

  15. The mesospheric sodium layer as a remotely, optically pumped magnetometer for investigation of Birkeland currents

    Science.gov (United States)

    Johnsen, Magnar G.; Matzka, Jürgen; Hoppe, Ulf-Peter

    2016-04-01

    By means of optical pumping, it is possible to use the naturally occurring sodium layer in the mesosphere to measure Earth's scalar magnetic field at ~90 km above ground. This is an altitude not accessible by other means than rockets, which only will provide point measurements of very short time scales. We are planning to modify the sodium lidar at ALOMAR in Northern Norway to be able, for the first time, to measure and monitor the magnetic field in situ in the high latitude mesosphere over longer time scales. The planned modifications to the lidar instrument will allow alternating between the new magnetometer mode and its present mode for atmospheric temperatures and winds. The technique, which has been proposed earlier for measurements at low or mid-latitudes for studies of Earth's internal magnetic field, will in our project be applied to high latitudes in the auroral zone. This opens for a completely new domain of measurements of externally generated geomagnetic variations related to currents in the magnetosphere-ionosphere system. In particular, we aim to measure the magnetic field variations in close vicinity to Birkeland currents associated with particle precipitation events penetrating to altitudes below 90 km and small-scale, discrete auroral arcs. It is, furthermore, anticipated that it will be possible to detect horizontal current structures in the E-layer on much smaller length scales than it is presently possible from ground observations alone. During the project we plan take advantage of the rich space science infrastructure located in northern Norway, including ALOMAR, EISCAT and the Tromsø Geophysical Observatory magnetometer network. If possible, we also aim to make measurements in conjunction with overpasses of the SWARM satellites.

  16. Studying the effects of classic hallucinogens in the treatment of alcoholism: rationale, methodology, and current research with psilocybin.

    Science.gov (United States)

    Bogenschutz, Michael P

    2013-03-01

    Recent developments in the study of classic hallucinogens, combined with a re-appraisal of the older literature, have led to a renewal of interest in possible therapeutic applications for these drugs, notably their application in the treatment of addictions. This article will first provide a brief review of the research literature providing direct and indirect support for the possible therapeutic effects of classic hallucinogens such as psilocybin and lysergic acid diethylamide (LSD) in the treatment of addictions. Having provided a rationale for clinical investigation in this area, we discuss design issues in clinical trials using classic hallucinogens, some of which are unique to this class of drug. We then discuss the current status of this field of research and design considerations in future randomized trials.

  17. How Do Clinicians Learn About Knowledge Translation? An Investigation of Current Web-Based Learning Opportunities

    OpenAIRE

    Damarell, Raechel A; Tieman, Jennifer J

    2017-01-01

    Background Clinicians are important stakeholders in the translation of well-designed research evidence into clinical practice for optimal patient care. However, the application of knowledge translation (KT) theories and processes may present conceptual and practical challenges for clinicians. Online learning platforms are an effective means of delivering KT education, providing an interactive, time-efficient, and affordable alternative to face-to-face education programs. Objective This study ...

  18. Current knowledge on the genetics of autism and propositions for future research.

    Science.gov (United States)

    Bourgeron, Thomas

    2016-01-01

    Autism spectrum disorders (ASD) are a heterogeneous group of neuropsychiatric disorders characterized by problems in social communication, as well as by the presence of restricted interests, stereotyped and repetitive behaviours. In the last 40years, genetic studies have provided crucial information on the causes of ASD and its diversity. In this article, I will first review the current knowledge on the genetics of ASD and then suggest three propositions to foster research in this field. Twin and familial studies estimated the heritability of ASD to be 50%. While most of the inherited part of ASD is captured by common variants, our current knowledge on the genetics of ASD comes almost exclusively from the identification of highly penetrant de novo mutations through candidate gene or whole exome/genome sequencing studies. Approximately 10% of patients with ASD, especially those with intellectual disability, are carriers of de novo copy-number (CNV) or single nucleotide variants (SNV) affecting clinically relevant genes for ASD. Given the function of these genes, it was hypothesized that abnormal synaptic plasticity and failure of neuronal/synaptic homeostasis could increase the risk of ASD. In addition to these discoveries, three propositions coming from institutions, researchers and/or communities of patients and families can be made to foster research on ASD: (i) to use more dimensional and quantitative data than diagnostic categories; (ii) to increase data sharing and research on genetic and brain diversity in human populations; (iii) to involve patients and relatives as participants for research. Hopefully, this knowledge will lead to a better diagnosis, care and integration of individuals with ASD.

  19. Using ASM Podcasts to Excite Undergraduate Students about Current Microbiological Research

    Directory of Open Access Journals (Sweden)

    Stacey E. Lettini

    2014-08-01

    Full Text Available Innovative technology is often used as a mechanism to engage students in and out of the classroom and can be used to increase critical thinking skills. Podcasts are an excellent way to introduce students to current topics and research in microbiology. The American Society for Microbiology (ASM produces three podcasts that are microbiologically focused: This Week in Microbiology (TWiM, This Week in Parasitology (TWiP, and This Week in Virology (TWiV. These podcasts are usually presented in a manner similar to a journal club, as the presenters regularly invite guests to discuss current research papers. Since students often find reading scientific literature difficult and get bogged down in the details rather than seeing the over-arching purpose of a paper, these podcasts have been used in a General Microbiology course to introduce recent research articles. The students were first assigned an original research article to read and review, and they were asked to generate questions pertaining to things they did not understand. Next, students listened to the corresponding podcast that discussed the article and used it to answer their questions. This was followed by a classroom discussion of the article and the podcast. The ASM podcast helped to demystify original research by providing details of the experimental design and presentation of the results in a language that is more casual and relatable. Students demonstrated greater critical thinking and comprehension of microbiology literature after listening to the podcast. This activity can be used in a variety of courses in the biology curriculum.

  20. Current research and potential applications of the Concealed Information Test: An overview

    Directory of Open Access Journals (Sweden)

    Gershon eBen-Shakhar

    2012-09-01

    Full Text Available Research interest in psychophysiological detection of deception has significantly increased since the September 11 terror attack in the USA. In particular, the Concealed Information Test (CIT, designed to detect memory traces that can connect suspects to a certain crime, has been extensively studied. In this paper I will briefly review several psychophysiological detection paradigms that have been studied, with a focus on the CIT. The theoretical background of the CIT, its strength and weaknesses, its potential applications as well as research finings related to its validity, (based on a recent mata-analytic study, will be discussed. Several novel research directions, with a focus on factors that may affect CIT detection in realistic settings (e.g., memory for crime details; the effect of emotional stress during crime execution will be described. Additionally, research focusing on mal-intentions and attempts to detect terror networks using information gathered from groups of suspects using both the standard CIT and the searching CIT will be reviewed. Finally, implications of current research to the actual application of the CIT will be discussed and several recommendations that can enhance the use of the CIT will be made.

  1. Prebiotics and the health benefits of fiber: current regulatory status, future research, and goals.

    Science.gov (United States)

    Brownawell, Amy M; Caers, Wim; Gibson, Glenn R; Kendall, Cyril W C; Lewis, Kara D; Ringel, Yehuda; Slavin, Joanne L

    2012-05-01

    First defined in the mid-1990s, prebiotics, which alter the composition and activity of gastrointestinal (GI) microbiota to improve health and well-being, have generated scientific and consumer interest and regulatory debate. The Life Sciences Research Organization, Inc. (LSRO) held a workshop, Prebiotics and the Health Benefits of Fiber: Future Research and Goals, in February 2011 to assess the current state of the science and the international regulatory environment for prebiotics, identify research gaps, and create a strategy for future research. A developing body of evidence supports a role for prebiotics in reducing the risk and severity of GI infection and inflammation, including diarrhea, inflammatory bowel disease, and ulcerative colitis as well as bowel function disorders, including irritable bowel syndrome. Prebiotics also increase the bioavailability and uptake of minerals and data suggest that they reduce the risk of obesity by promoting satiety and weight loss. Additional research is needed to define the relationship between the consumption of different prebiotics and improvement of human health. New information derived from the characterization of the composition and function of different prebiotics as well as the interactions among and between gut microbiota and the human host would improve our understanding of the effects of prebiotics on health and disease and could assist in surmounting regulatory issues related to prebiotic use.

  2. Current Realities and Future Possibilities: Language and science literacy—empowering research and informing instruction

    Science.gov (United States)

    Yore, Larry D.; Treagust, David F.

    2006-02-01

    In this final article, we briefly review and synthesize the science and language research and practice that arose from the current literature and presentations at an international conference, referred to as the first “Island Conference”. We add to the synthesis of the articles the conference deliberations and on-going discussions of the field and also offer our views as to how such contributions can take place. These central issues—the definition of science literacy; the models of learning, discourse, reading, and writing and their underlying pedagogical assumptions; the roles of discourse in doing, teaching, and learning science; and the demands on teacher education and professional development in the current reforms in language and science education—provide points of departure for discussion of four possible new considerations to research in this field of endeavour that could contribute to a broader and productive scholarship and deeper and enriched understanding of both teaching and learning. These considerations, each from well-established fields of research literature, are the need to develop support for a contemporary view of science literacy, the role of metacognition in science learning generally, the role of multiple representations in knowledge building and science literacy, and the need for more focused teacher education and professional development programmes.

  3. A comparative study: the impact of different lipid extraction methods on current microalgal lipid research.

    Science.gov (United States)

    Li, Yan; Ghasemi Naghdi, Forough; Garg, Sourabh; Adarme-Vega, Tania Catalina; Thurecht, Kristofer J; Ghafor, Wael Abdul; Tannock, Simon; Schenk, Peer M

    2014-01-24

    Microalgae cells have the potential to rapidly accumulate lipids, such as triacylglycerides that contain fatty acids important for high value fatty acids (e.g., EPA and DHA) and/or biodiesel production. However, lipid extraction methods for microalgae cells are not well established, and there is currently no standard extraction method for the determination of the fatty acid content of microalgae. This has caused a few problems in microlagal biofuel research due to the bias derived from different extraction methods. Therefore, this study used several extraction methods for fatty acid analysis on marine microalga Tetraselmis sp. M8, aiming to assess the potential impact of different extractions on current microalgal lipid research. These methods included classical Bligh & Dyer lipid extraction, two other chemical extractions using different solvents and sonication, direct saponification and supercritical CO₂ extraction. Soxhlet-based extraction was used to weigh out the importance of solvent polarity in the algal oil extraction. Coupled with GC/MS, a Thermogravimetric Analyser was used to improve the quantification of microalgal lipid extractions. Among these extractions, significant differences were observed in both, extract yield and fatty acid composition. The supercritical extraction technique stood out most for effective extraction of microalgal lipids, especially for long chain unsaturated fatty acids. The results highlight the necessity for comparative analyses of microalgae fatty acids and careful choice and validation of analytical methodology in microalgal lipid research.

  4. Towards Current Profile Control in ITER: Potential Approaches and Research Needs

    Science.gov (United States)

    Schuster, E.; Barton, J. E.; Wehner, W. P.

    2014-10-01

    Many challenging plasma control problems still need to be addressed in order for the ITER Plasma Control System (PCS) to be able to successfully achieve the ITER project goals. For instance, setting up a suitable toroidal current density profile is key for one possible advanced scenario characterized by noninductive sustainment of the plasma current and steady-state operation. The nonlinearity and high dimensionality exhibited by the plasma demand a model-based current-profile control synthesis procedure that can accommodate this complexity through embedding the known physics within the design. The development of a model capturing the dynamics of the plasma relevant for control design enables not only the design of feedback controllers for regulation or tracking but also the design of optimal feedforward controllers for a systematic model-based approach to scenario planning, the design of state estimators for a reliable real-time reconstruction of the plasma internal profiles based on limited and noisy diagnostics, and the development of a fast predictive simulation code for closed-loop performance evaluation before implementation. Progress towards control-oriented modeling of the current profile evolution and associated control design has been reported following both data-driven and first-principles-driven approaches. An overview of these two approaches will be provided, as well as a discussion on research needs associated with each one of the model applications described above. Supported by the US Department of Energy under DE-SC0001334 and DE-SC0010661.

  5. Large-Eddy Simulation: Current Capabilities, Recommended Practices, and Future Research

    Science.gov (United States)

    Georgiadis, Nicholas J.; Rizzetta, Donald P.; Fureby, Christer

    2009-01-01

    This paper presents the results of an activity by the Large Eddy Simulation (LES) Working Group of the AIAA Fluid Dynamics Technical Committee to (1) address the current capabilities of LES, (2) outline recommended practices and key considerations for using LES, and (3) identify future research needs to advance the capabilities and reliability of LES for analysis of turbulent flows. To address the current capabilities and future needs, a survey comprised of eleven questions was posed to LES Working Group members to assemble a broad range of perspectives on important topics related to LES. The responses to these survey questions are summarized with the intent not to be a comprehensive dictate on LES, but rather the perspective of one group on some important issues. A list of recommended practices is also provided, which does not treat all aspects of a LES, but provides guidance on some of the key areas that should be considered.

  6. Current trends in research and clinical issues in the study of personality and its disorders

    DEFF Research Database (Denmark)

    Simonsen, Erik; Sørensen, Per; Pedersen, Liselotte

    2014-01-01

    lecture (Simonsen), a young researchers' symposium (Hopwood, Sharp, and Kaess), and special lectures on the Danish philosopher Soeren Kierkegaard and the poet Hans Christian Andersen. In this article we will survey the presentations and highlight the important issues in order to underline the current......The International Society for the Study of Personality Disorders (ISSPD) celebrated its 25th anniversary in September 2013 in Copenhagen and commemorated the First International Congress at the same site. The overall theme of the congress was "Bridging Personality and Psychopathology: The Person...... Behind the Illness." More than 400 abstracts were submitted, and the program included 8 keynote presentations, 18 invited symposia, a debate on current controversial issues in the classification of personality disorders (Fossati, Tyrer, Livesley, and Krueger), an ISSPD award lecture (Silk), a jubilee...

  7. Experimental investigation of the effect of titanium dioxide and barium titanate additives on DC transient currents in low density polyethylene

    DEFF Research Database (Denmark)

    Khalil, M.S; Henk, Peter O; Henriksen, Mogens

    1988-01-01

    The effect of titanium dioxide as a semiconductive additive and barium titanate as a highly polar additive on the DC transient currents in low-density polyethylene is investigated. Experiments were made using thick specimens under a high electric field (>25×106 V/m) and a constant temperature of 40...

  8. Current research in nuclear medicine and molecular imaging: highlights of the 23rd Annual EANM Congress.

    Science.gov (United States)

    Carrió, Ignasi

    2011-02-01

    The most recent research developments in nuclear medicine and molecular imaging were presented at the 2010 Annual Congress of the EANM. This review summarizes some of the most relevant contributions made in the fields of oncology, cardiovascular science, neurology and psychiatry, technological innovation and novel tracers. Presentations covered basic and clinical research in nuclear medicine and molecular imaging, and diagnostic and therapeutic applications of radioisotopes and radiopharmaceuticals on a global scale. The results reported demonstrate that investigative strategies using nuclear medicine techniques facilitate effective diagnosis and management of patients with most prevalent disease states. At the same time novel tracers and technologies are being explored, which hold promise for future new applications of nuclear medicine and molecular imaging in research and clinical practice.

  9. Third-generation biofuels: current and future research on microalgal lipid biotechnology

    Directory of Open Access Journals (Sweden)

    Li-Beisson Yonghua

    2013-11-01

    Full Text Available One pressing issue faced by modern societies is to develop renewable energy for transportation. Microalgal biomass offers an attractive solution due to its high (annual surface biomass productivity, efficient conversion of solar energy into chemical energy and the ability to grow on non-agricultural land. Despite these considerable advantages, microalgal biofuels are not yet commercially sustainable. Major challenges lie in improving both cultivation technologies and microalgal strains. A microalgal crop species is yet to emerge. In this review, we focus on researches aiming at understanding and harnessing lipid metabolism in microalgae in view of producing lipid-based biofuels such as biodiesel. Current biotechnological challenges and key progresses made in the development of algal models, genetic tools and lipid metabolic engineering strategies are reviewed. Possible future research directions to increase oil yields in microalgae are also highlighted.

  10. Bridging prediction and attention in current research on perception and action.

    Science.gov (United States)

    Schröger, Erich; Kotz, Sonja A; SanMiguel, Iria

    2015-11-11

    Prediction and attention are fundamental brain functions in the service of perception and action. Theories on prediction relate to neural (mental) models inferring about (present or future) sensory or action-related information, whereas theories of attention are about the control of information flow underlying perception and action. Both concepts are related and not always clearly distinguishable. The special issue includes current research on prediction and attention in various subfields of perception and action. It especially considers interactions between predictive and attentive processes, which constitute a newly emerging and highly interesting field of research. As outlined in this editorial, the contributions in this special issue allow specifying as well as bridging concepts on prediction and attention. The joint consideration of prediction and attention also reveals common functional principles of perception and action.

  11. Ethics of medical care and clinical research: a qualitative study of principal investigators in biomedical HIV prevention research.

    Science.gov (United States)

    Haire, Bridget G

    2013-04-01

    In clinical research there is a tension between the role of a doctor, who must serve the best interests of the patient, and the role of the researcher, who must produce knowledge that may not have any immediate benefits for the research participant. This tension is exacerbated in HIV research in low and middle income countries, which frequently uncovers comorbidities other than the condition under study. Some bioethicists argue that as the goals of medicine and those of research are distinct, it is a mistake for researchers to assume therapeutic responsibilities while engaging in research. Others propose that there is a duty of care, but disagree as to how this is limited and specified. In this qualitative study, principal investigators from HIV prevention trials discuss their experience of providing medical benefits to participants within the context of conducting research into HIV biomedical prevention technologies. They describe the limitations imposed at times by funders and at times by infrastructure constraints, and canvass the importance of ancillary care provision and capacity building in trial communities. The views of the principal investigators are compatible with the perspective that there is a duty of care, limited by the nature of the research, the depth of the relationship between research and participant, and the capacity of the research site. The therapeutic orientation in HIV prevention trial appears to be indivisible from competent research practise by making concrete and appropriate benefits available to trial participants and their communities that support rather than compete with local infrastructure.

  12. Grand Research Plan for Neural Circuits of Emotion and Memory-Current status of neural circuit studies in China

    Institute of Scientific and Technical Information of China (English)

    Yuan-Gui Zhu; He-Qi Cao; Er-Dan Dong

    2013-01-01

    During recent years,major advances have been made in neuroscience,i.e.,asynchronous release,three-dimensional structural data sets,saliency maps,magnesium in brain research,and new functional roles of long non-coding RNAs.Especially,the development of optogenetic technology provides access to important information about relevant neural circuits by allowing the activation of specific neurons in awake mammals and directly observing the resulting behavior.The Grand Research Plan for Neural Circuits of Emotion and Memory was launched by the National Natural Science Foundation of China.It takes emotion and memory as its main objects,making the best use of cutting-edge technologies from medical science,life science and information science.In this paper,we outline the current status of neural circuit studies in China and the technologies and methodologies being applied,as well as studies related to the impairments of emotion and memory.In this phase,we are making efforts to repair the current deficiencies by making adjustments,mainly involving four aspects of core scientific issues to investigate these circuits at multiple levels.Five research directions have been taken to solve important scientific problems while the Grand Research Plan is implemented.Future research into this area will be multimodal,incorporating a range of methods and sciences into each project.Addressing these issues will ensure a bright future,major discoveries,and a higher level of treatment for all affected by debilitating brain illnesses.

  13. Investigation on the Arc Ignition Characteristics and Energy Absorption of Liquid Metal Current Limiter Based on Self-Pinch Effect

    Institute of Scientific and Technical Information of China (English)

    JU Xingbao; SUN Haishun; YANG Zhuo; ZHANG Junmin

    2016-01-01

    The GaInSn liquid metal current limiter based on the fluid pinch effect has broad application prospects due to its particular properties.However,the limited rated current and ability of power dissipation are the critical problems for its wide application.Firstly,the temperature distribution of the liquid metal current limiter (LMCL) was obtained by experiments with a rated current of 1 kA and the arc ignition phenomenon was observed with 1.5 kA,which indicates that the rated current is mainly limited by the arc rather than the high temperature compared to the traditional switchgears.Furthermore,an improved method is proposed by adding the paralleled pure resistance,impedance or another LMCL element to protect the setup from the fault energy concentration in the setup.The problem of a slower arc voltage increasing rate can be solved by adding a paralleled impedance with suitable parameters.Finally,the current limiting properties based on the improved method were investigated and the alternating oscillating current was found between two paralleled LMCL elements owing to their deviation of arc ignition in reality.

  14. An in vitro investigation of two currently marketed dentin tubule occlusion dentifrices.

    Science.gov (United States)

    Parkinson, Charles R; Willson, Richard J

    2011-01-01

    The objective of this study was to evaluate the relative level of dentin tubule occlusion afforded by two dentifrices specifically developed to occlude dentin tubules, following finger-applied dab-on application and by repeated brushing, in a longitudinal acid-challenge-based dentin disk model. The impact of a dietary acid alone (grapefruit juice) on the level of dentin tubule occlusion conferred by each product following dab-on application was also explored in a separate short-term stand-alone exploratory dentin disk-based in vitro study. For the longitudinal study, 120 bovine dentin discs, polished and etched in citric acid for two minutes to provide a smooth dentin surface with patent tubules, were divided into three treatment groups and subjected to a finger application of the dentifrice only, or a combination of finger application and brushing. Prior to and between treatments, the dentin samples were stored in saliva (for > 60 minutes). The test products were an 8% w/w strontium acetate dentifrice (currently marketed as Sensodyne Rapid Relief), an arginine-based dentifrice (marketed as Colgate Sensitive Pro-Relief), and deionized water. For the exploratory acid resistance study, 24 dentin samples were divided into two treatment groups. Treatment consisted of a single dab-on application with the test dentifrices to the hydrated surface of dentin, followed by exposure to either a 30-second or 10-minute grapefruit juice acid challenge. For both models, at the end of each treatment period, the samples were removed for scanning electron microscopy analysis and graded on a categorical visual scale. All data were analyzed statistically by unpaired t-test comparison. In the longitudinal (four-day) model, the strontium acetate-based dentifrice occluded dentin tubules significantly better than the currently marketed arginine-based dentifrice post-dab-on treatment and grapefruit juice challenge (p < 0.0001). At all other time points, the strontium acetate dentifrice

  15. A Literature Investigation about Electrospinning and Nanofibers: Historical Trends, Current Status and Future Challenges.

    Science.gov (United States)

    Nascimento, Marcio L F; Araújo, Evando S; Cordeiro, Erlon R; de Oliveira, Ariadne H P; de Oliveira, Helinando P

    2015-01-01

    The development of new fibrilar materials based on electrospinning (ES) technique has a notable history of nearly four centuries of discoveries and results. The eletrospinning manufacturing is one of the most widely reported methods for nanofiber (NF) manufacturing, providing security, high quality and productivity. In spite of the first patent about electrospinning has been applied in April 5(th), 1900 by John Francis Cooley, a historical perspective (since 1600s) about this amazing discovery represents an important step for future applications. Nanofibers have been considered one of the top interesting fundamental study objects for academicians, and greatest intriguing business materials for modern industry. As a consequence, lucrative organizations and companies have explored the relevance of nanofibers. In this paper, the quantity of published manuscripts and patent inventions is presented and the correlation of research activities to the production of new electrospinning materials is shown. China and the United States have been leading in electrospinning and nanofibers development. The company triumph is mostly dependent on applications improvement relevant for broader business society. A dramatic rise of interest in nanofibers produced by electrospinning technique has been confirmed due to the publication data, author's affiliation, keywords, and essential characterization procedures. Is has been shown that the number of publications on electrospinning and nanofibers researches from academic institutions is higher than industrial laboratories. More than 1,891 patents using the term "electrospinning" and 2,960 with the term "nanofibers" according to the European Patent Office at title or abstract have been filed around the world up to 2013. These numbers just continue to increase along with worldwide ES-related sales. Curiously, for the same period 11,973 electrospinning documents and 18,679 nanofibers-related (mainly manuscripts) were published considering

  16. Wi-Fi and health: review of current status of research.

    Science.gov (United States)

    Foster, Kenneth R; Moulder, John E

    2013-12-01

    This review summarizes the current state of research on possible health effects of Wi-Fi (a commercial name for IEEE 802.11-compliant wireless networking). In response to public concerns about health effects of Wi-Fi and wireless networks and calls by government agencies for research on possible health and safety issues with the technology, a considerable amount of technology-specific research has been completed. A series of high quality engineering studies have provided a good, but not complete, understanding of the levels of radiofrequency (RF) exposure to individuals from Wi-Fi. The limited number of technology-specific bioeffects studies done to date are very mixed in terms of quality and outcome. Unequivocally, the RF exposures from Wi-Fi and wireless networks are far below U.S. and international exposure limits for RF energy. While several studies report biological effects due to Wi-Fi-type exposures, technical limitations prevent drawing conclusions from them about possible health risks of the technology. The review concludes with suggestions for future research on the topic.

  17. Ocean Science for Decision-Making: Current Activities of the National Research Council's Ocean Studies Board

    Science.gov (United States)

    Roberts, S.; Glickson, D.; Mengelt, C.; Forrest, S.; Waddell, K.

    2012-12-01

    The National Research Council is a private, nonprofit organization chartered by Congress in 1916 as an expansion of the U.S. National Academy of Sciences. Its mission is to improve the use of science in government decision making and public policy, increase public understanding, and promote the acquisition and dissemination of knowledge in matters involving science, engineering, technology, and health. Within the National Research Council, the Ocean Studies Board (OSB) mission is to explore the science, policies, and infrastructure needed to understand, manage, and conserve coastal and marine environments and resources. OSB undertakes studies and workshops on emerging scientific and policy issues at the request of federal agencies, Congress, and others; provides program reviews and guidance; and facilitates communication on oceanographic issues among different sectors. OSB also serves as the U.S. National Committee to the international, nongovernmental Scientific Committee on Oceanic Research (SCOR). OSB has produced reports on a wide range of topics of interest to researchers and educators, the federal government, the non-profit sector, and industry. Recent reports have focused on ecosystem services in the Gulf of Mexico after the Deepwater Horizon oil spill, sea level rise on the U.S. west coast, scientific ocean drilling needs and accomplishments, requirements for sustained ocean color measurements, critical infrastructure for ocean research, tsunami warning and preparedness, ocean acidification, and marine and hydrokinetic power resource assessments. Studies that are currently underway include responding to oil spills in the Arctic, evaluating the effectiveness of fishery stock rebuilding plans, and reviewing the National Ocean Acidification Research Plan. OSB plays an important role in helping create policy decisions and disseminating important information regarding various aspects of ocean science.

  18. An Investigation of Current and Future Data Systems in Numerical Meteorology

    Science.gov (United States)

    Diak, George R.; Burns, Barbara A.; Wu, Xiangqian

    1996-01-01

    The Advanced Microwave Sounding Unit (AMSU) and the Microwave Humidity Sounder (MHS) constitute the advanced microwave sounding system to be flown on the EOS-PM platform. Similar instruments (the AMSU-A corresponding to the AMSU and the AMSU-B corresponding to the MHS) are scheduled to become operational on the NOAA polar orbiting satellites beginning with NOAA-K. The unique characteristics of the AMSU-MHS instruments, as compared to the capabilities of their infrared and microwave predecessors, introduce new opportunities, and challenges, for operational retrievals of atmospheric structure. Not only will these new data improve present capabilities for the retrieval of atmospheric profiles of temperature and moisture, but they will provide the only opportunity for successfully retrieving atmospheric temperature and humidity profiles in the presence of modest amounts of cloud and precipitation. A complementary opportunity is presented by the potential of the AMSU-MHS to obtain information about the structure of clouds and precipitation. The data sets obtained will contribute to the current knowledge of global water and energy budgets, and provide critical information on the horizontal and vertical distribution of tropospheric water vapor, the spatial and temporal distribution of rain, and the relationship of cloud formation and dissipation to atmospheric dynamics and thermodynamics.

  19. An Experimental Investigation of Passive Variable-Pitch Vertical-Axis Ocean Current Turbine

    Directory of Open Access Journals (Sweden)

    Ridho Hantoro

    2011-04-01

    Full Text Available Vertical-axis hydrokinetic turbines with fixed pitch blades typically suffer from poor starting torque, low efficiency and shaking due to large fluctuations in both radial and tangential force with azimuth angle. Maximizing the turbine power output can be achieved only if the mechanism of generation of the hydrodynamic force on the blades is clearly identified and tools to design high-performance rotors are developed. This paper describes an initial experimental investigation to understand more of the performance on vertical-axis turbine related to the effect of fixed-pitch and passive variable-pitch application using airfoil NACA 0018. Comparative analysis according to aspects of rotation and tip speed ratios was discussed. Information regarding the changes of foil position in passive variable-pitch during rotation at a limited range of flow velocity variations test was obtained and analyzed.

  20. DNA typing in forensic medicine and in criminal investigations: a current survey

    Science.gov (United States)

    Benecke, Mark

    Since 1985 DNA typing of biological material has become one of the most powerful tools for personal identification in forensic medicine and in criminal investigations [1-6]. Classical DNA 〝fingerprinting'' is increasingly being replaced by polymerase chain reaction (PCR) based technology which detects very short polymorphic stretches of DNA [7-15]. DNA loci which forensic scientists study do not code for proteins, and they are spread over the whole genome [16, 17]. These loci are neutral, and few provide any information about individuals except for their identity. Minute amounts of biological material are sufficient for DNA typing. Many European countries are beginning to establish databases to store DNA profiles of crime scenes and known offenders. A brief overview is given of past and present DNA typing and the establishment of forensic DNA databases in Europe.