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Sample records for cu6sn5 imc layer

  1. Grain Growth Orientation and Anisotropy in Cu6Sn5 Intermetallic: Nanoindentation and Electron Backscatter Diffraction Analysis

    Science.gov (United States)

    Choudhury, Soud Farhan; Ladani, Leila

    2014-04-01

    As the size of joints in micro/nano-electronics diminishes, the role of intermetallic (IMC) layers becomes more significant. It was shown that solder joint strength is controlled largely by IMC strength at higher strain rates. Additionally, there is a possibility that very small joints are completely composed of IMCs. Further miniaturization of joints may result in statistical grain size effects. Therefore, it is essential to characterize IMC materials and understand their anisotropic mechanical properties. One of the most common types of IMCs in microelectronic joints is Cu6Sn5, which is formed in a variety of bonding materials with different compositions of Sn, Cu, and Ag. This work studies through nanoindentation elastic-plastic properties of a single grain of Cu6Sn5 IMC in a Sn-3.5Ag/Cu system with reflow soldering. Elastic properties such as elastic modulus and hardness were determined from the nanoindentation load-depth curve. The reverse analysis model described by Dao et al. was used to extract plastic properties such as yield strength and strain hardening exponent from nanoindentation data. Care was taken to achieve indentation of single grains with sufficient accuracy and repeatability. Electron backscatter diffraction (EBSD) mapping was used to determine orientation of Cu6Sn5 grains and to relate the orientation with the load-depth curve results of nanoindentation and the corresponding elastic and plastic properties. The EBSD results indicated that the Cu6Sn5 crystal structure is hexagonal. Columnar growth of the Cu6Sn5 grains was observed as the grains mostly grew along the c-axis of the crystal. Indentation of different grains parallel to the basal plane showed no significant difference in mechanical properties.

  2. Creep and Mechanical Properties of Cu6Sn5 and (Cu,Ni)6Sn5 at Elevated Temperatures

    Science.gov (United States)

    Mu, Dekui; Huang, Han; McDonald, Stuart D.; Nogita, Kazuhiro

    2013-02-01

    Cu6Sn5 is the most common and important intermetallic compound (IMC) formed between Sn-based solders and Cu substrates during soldering. The Cu6Sn5 IMC exhibits significantly different thermomechanical properties from the solder alloys and the substrate. The progress of high-density three-dimensional (3D) electrical packaging technologies has led to increased operating temperatures, and interfacial Cu6Sn5 accounts for a larger volume fraction of the fine-pitch solder joints in these packages. Knowledge of creep and the mechanical behavior of Cu6Sn5 at elevated temperatures is therefore essential to understanding the deformation of a lead-free solder joint in service. In this work, the effects of temperature and Ni solubility on creep and mechanical properties of Cu6Sn5 were investigated using energy-dispersive x-ray spectroscopy and nanoindentation. The reduced modulus and hardness of Cu6Sn5 were found to decrease as temperature increased from 25°C to 150°C. The addition of Ni increased the reduced modulus and hardness of Cu6Sn5 and had different effects on the creep of Cu6Sn5 at room and elevated temperatures.

  3. Cu6Sn5-TiC-C nanocomposite anodes for high-performance sodium-ion batteries

    Science.gov (United States)

    Kim, Il Tae; Allcorn, Eric; Manthiram, Arumugam

    2015-05-01

    Cu6Sn5 alloy nanoparticles dispersed in a TiC and C conductive matrix have been developed via high energy mechanical milling (HEMM), and the resulting Cu6Sn5-TiC-C nanocomposite has been assessed as anodes for sodium-ion batteries. Composite anodes of Sn-C exhibit poor cyclic performance even with the introduction of 2 vol. % fluoroethylene carbonate (FEC) additive into the electrolyte. In contrast, Cu6Sn5-TiC-C nanocomposite anodes exhibit stable cycle life corresponding to a capacity retention of ∼80% at 40 cycles and high-rate performance with a capacity retention of ∼62% at 3000 mA g-1. These superior performance metrics is ascribed to the well-developed electrochemically active nanocrystalline material (Cu6Sn5) as well as a hybrid conductive matrix (TiC and C). The incorporation of 2 vol. % FEC additive into the electrolyte further improves the performance of Cu6Sn5-TiC-C nanocomposite to display a capacity retention of ∼94% at 250 cycles and high-rate capacity retention of ∼82% at 5000 mA g-1, which are attributed to the formation of a thin and stable SEI layer in presence of FEC.

  4. Three Dimensional Characterization of Tin Crystallography and Cu6Sn5 Intermetallics in Solder Joints by Multiscale Tomography

    Science.gov (United States)

    Kirubanandham, A.; Lujan-Regalado, I.; Vallabhaneni, R.; Chawla, N.

    2016-11-01

    Decreasing pitch size in electronic packaging has resulted in a drastic decrease in solder volumes. The Sn grain crystallography and fraction of intermetallic compounds (IMCs) in small-scale solder joints evolve much differently at the smaller length scales. A cross-sectional study limits the morphological analysis of microstructural features to two dimensions. This study utilizes serial sectioning technique in conjunction with electron backscatter diffraction to investigate the crystallographic orientation of both Sn grains and Cu6Sn5 IMCs in Cu/Pure Sn/Cu solder joints in three dimensional (3D). Quantification of grain aspect ratio is affected by local cooling rate differences within the solder volume. Backscatter electron imaging and focused ion beam serial sectioning enabled the visualization of morphology of both nanosized Cu6Sn5 IMCs and the hollow hexagonal morphology type Cu6Sn5 IMCs in 3D. Quantification and visualization of microstructural features in 3D thus enable us to better understand the microstructure and deformation mechanics within these small scale solder joints.

  5. 热迁移对Cu/Sn/Cu焊点液-固界面Cu6Sn5生长动力学的影响∗%Effect of thermomigration on the growth kinetics of Cu6Sn5 at liquid-solid interfaces in Cu/Sn/Cu solder joints

    Institute of Scientific and Technical Information of China (English)

    赵宁; 钟毅; 黄明亮; 马海涛; 刘小平

    2015-01-01

    With the continuous miniaturization of electronic packaging, micro bumps for chip interconnects are smaller in size, and thus the reliability of interconnects becomes more and more sensitive to the formation and growth of intermetallic compounds (IMCs) at liquid-solid interface during soldering. Thermomigration (TM) is one of the simultaneous heat and mass transfer phenomena, and occurs in a mixture under certain external temperature gradient. In the process of interconnection, micro bumps usually undergo multiple reflows during which nonuniform temperature distribution may occur, resulting in TM of metal atoms. Since the interdiffusion of atoms between solders and under bump metallization (UBM) dominates the formation of interfacial IMCs, TM which enhances the directional diffusion of metal atoms and induces the redistribution of elements, will markedly influence the growth behaviors of interfacial IMCs and consequently the reliability of solder joints. The diffusivity of atoms in liquid solder is significantly larger than that in solid solder and in consequence a small temperature gradient may induce the mass migration of atoms. As a result, the growth of interfacial IMCs becomes more sensitive to temperature difference between solder joints in soldering process. So far, however, few studies have focused on liquid state TM in solder joints, and the growth kinetics of interfacial IMCs under TM during soldering is still unknown to us. In this study, Cu/Sn/Cu solder joints are used to investigate the migration behavior of Cu atoms and its effect on the growth kinetics of interfacial Cu6Sn5 under temperature gradients of 35.33 ◦C/cm at 250 ◦C and 40.0 ◦C/cm at 280 ◦C, respectively. TM experiments are carried out by reflowing the Cu/Sn/Cu interconnects on a hot plate at 250 ◦C and 280 ◦C for different durations. For comparison, isothermal aging experiments are conducted in a high temperature chamber under the same temperatures and reaction durations

  6. Mendapatkan Young’s Modulus Fasa Cu6Sn5 dengan Teknik Ultrasonik dan Teori Komposit

    Directory of Open Access Journals (Sweden)

    Ellyza Herda

    2015-09-01

    Full Text Available The purpose of this study is to obtain the Young’s Modulus (elastic property of Cu6Sn5 phase by using ultrasonic technique and composite theory. Alloy with the following composition (weight percent = wt%: 15.00 % Cu and 85 % Sn was fabricated by casting method. Phases identification were determined by using X-ray Diffraction (XRD, Differential Scanning Calorimeter (DSC, and Scanning Electron Microscope (SEM + EDAX (Energy Dispersive X-ray Analysis. A non destructive technique is preferable evaluation method for evaluation the elastic property of material, that is by utilizing longitudinal and transversal waves velocity employed by ultrasonic pulse-echo method. X-ray diffraction, DSC, and SEM+EDAX analysis indicate that the fabricated Cu-85%Sn alloy produce a composite in situ material which consist of Sn as a matrix (0.67 volume fraction and Cu6Sn5 phase as a reinforcing material (0.33 volume fraction. The Young’s Modulus value of Cu-85%Sn is 67.7 GPa. This value is base on the calculating result on the longitudinal and transversal waves velocity. In order to obtain the Young’s Modulus of reinforcement (Cu6Sn5 phase the composite theory was applied to this material (Cu-85%Sn, and the resulted value is 103.8 GPa.

  7. The influence of Ni additions on the relative stability of η and η′ Cu6Sn5

    KAUST Repository

    Schwingenschlögl, Udo

    2010-02-09

    We investigate how 5 at. % Ni influences the relative stability of η and η′ Cu6Sn5. Synchrotron x-ray diffraction shows that, while Cu6Sn5 exists as η′ at 25 and 150 °C and transforms to η on heating to 200 °C, Cu5.5Ni0.5Sn5 is best fit to η throughout 25–200 °C. Our first principles calculations predict that η′ is stable at T=0 K in both Cu6Sn5 and Cu5.5Ni0.5Sn5, but that the energy difference is substantially reduced from 1.21 to 0.90 eV per 22 atom cell by the Ni addition. This effect is attributed to Ni developing distinct bonding to both Cu and Sn in the η phase.

  8. Effect of Lanthanum on Driving Force for Cu6Sn5 Growth and Improvement of Solder Joint Reliability

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    By means of adding low content of rare earth element La into Sn60-Pb40 solder alloy, the growth of Cu6Sn5 intermetallic compound at the interface of solder joint is hindered, and the thermal fatigue life of solder joint is increased by 2 times. The results of thermodynamic calculation based on diffusion kinetics show that, the driving force for Cu6Sn5 growth is lowered by adding small content of La in Sn60-Pb40 solder alloy. Meanwhile, there is an effective local mole fraction range of La, in which, 0.18% is the limited value and 0.08% is the best value.

  9. Hexagonal-Rod Growth Mechanism and Kinetics of the Primary Cu6Sn5 Phase in Liquid Sn-Based Solder

    Science.gov (United States)

    Zhang, Z. H.; Cao, H. J.; Yang, H. F.; Li, M. Y.; Yu, Y. X.

    2016-11-01

    A hexagonal-rod growth mechanism is proposed to describe the growth behavior of the primary Cu6Sn5 phase in liquid Sn-based solder. After Sn-6.5 at.%Cu solder had been maintained at 250°C for 10 h, a large number of hexagonal-rod-type Cu6Sn5 grains were found to have separated within it. Our observations show that these hexagonal rods had side facets in the { 10overline{1} 0}_{η } family and round ends close to the {0002}η family. Moreover, the nucleation of the hexagonal rods was studied, and the corresponding growth kinetics found to be governed by a Cu-supply-controlled mechanism rather than an interfacial-reaction-controlled or Cu-diffusion-limited mechanism. More importantly, the anisotropic growth of the Cu6Sn5 phase was confirmed to be the dominant reason for production of these primary hexagonal rods with high aspect ratio. This may represent an avenue for synthesis of nanosized Cu6Sn5 single crystals for use as anode materials in lithium-ion batteries. Additionally, our Cu6Sn5 hexagonal-rod growth mechanism may provide insight into morphological and kinetic studies on interfacial Cu6Sn5 grains and similar intermetallics.

  10. Influence of Dopant on Growth of Intermetallic Layers in Sn-Ag-Cu Solder Joints

    Science.gov (United States)

    Li, G. Y.; Bi, X. D.; Chen, Q.; Shi, X. Q.

    2011-02-01

    The interfacial interaction between Cu substrates and Sn-3.5Ag-0.7Cu- xSb ( x = 0, 0.2, 0.5, 0.8, 1.0, 1.5, and 2.0) solder alloys has been investigated under different isothermal aging temperatures of 100°C, 150°C, and 190°C. Scanning electron microscopy (SEM) was used to measure the thickness of the intermetallic compound (IMC) layer and observe the microstructural evolution of the solder joints. The IMC phases were identified by energy-dispersive x-ray spectroscopy (EDX) and x-ray diffractometry (XRD). The growth of both the Cu6Sn5 and Cu3Sn IMC layers at the interface between the Cu substrate and the solder fits a power-law relationship with the exponent ranging from 0.42 to 0.83, which suggests that the IMC growth is primarily controlled by diffusion but may also be influenced by interface reactions. The activation energies and interdiffusion coefficients of the IMC formation of seven solder alloys were determined. The addition of Sb has a strong influence on the growth of the Cu6Sn5 layer, but very little influence on the formation of the Cu3Sn IMC phase. The thickness of the Cu3Sn layer rapidly increases with aging time and temperature, whereas the thickness of the Cu6Sn5 layer increases slowly. This is probably due to the formation of Cu3Sn at the interface between two IMC phases, which occurs with consumption of Cu6Sn5. Adding antimony to Sn-3.5Ag-0.7Cu solder can evidently increase the activation energy of Cu6Sn5 IMC formation, reduce the atomic diffusion rate, and thus inhibit excessive growth of Cu6Sn5 IMCs. This study suggests that grain boundary pinning is one of the most important mechanisms for inhibiting the growth of Cu6Sn5 IMCs in such solder joints when Sb is added.

  11. 电化学阻抗谱法研究温度对三维多孔Cu6Sn5合金电极嵌锂过程的影响%Electrochemical Impedance Spectroscopy Study on Effects of Temperature on the Lithiation Process of 3-Dimensional Porous Cu6Sns Alloy Electrode

    Institute of Scientific and Technical Information of China (English)

    樊小勇; 王晶晶; 李严; 曹桂铭; 史晓媛; 黄令; 孙世刚; 李东林

    2011-01-01

    Porous Cu was fabricated by electrodepositing using hydrogen bubbles as the dynamic template,and subsequently treated by annealing to increase the structural stability. The 3-dimensional porous Cu6Sn5 alloy electrode was prepared by electrodepositing using the porous Cu as the substrate. The lithiation/delithiation potentials of 3-dimensional porous Cu6Sn5 were investigated by cyclic voltammetry. The initial lithiation process of 3-dimensional porous Cu6Sn5 alloy electrode at different temperature was studied by electrochemical impedance spectroscopy. The results indicate that the Nyquist plots are composed of three regions in the main lithiation range: high frequency arc represents solid electrolyte interphase(SEI) impedance, middle frequency arc represents charge transfer impedance, and low frequency arc represents phase transformation impedance.The variation of the electrochemical impedance versus temperature was analyzed by simulating the experimental data using appropriate equivalent circuit.%采用氢气泡为动力学模板电沉积获得多孔铜,通过热处理增强其结构稳定性,并以该多孔铜为基底电沉积获得三维多孔Cu6Sn5合金电极.采用循环伏安法研究了三维多孔Cu6Sn5合金电极的嵌/脱锂电位.采用电化学阻抗谱研究了三维多孔Cu6Sn5合金电极在不同温度下的首次嵌锂过程.结果显示,在主要的嵌锂区间内,三维多孔Cu6Sn5合金电极的Nyquist图由锂离子穿过电极表面SEI膜阻抗的高频圆弧、电荷传递阻抗的中频圆弧和相变阻抗的低频圆弧3部分组成.因此,选择合适的等效电路对阻抗谱进行了模拟,并分析了其随温度的变化规律.

  12. Abnormal accumulation of IMC at cathode during electromigration in SnAgCu solder joint%SnAgCu焊点电迁移诱发IMC阴极异常堆积

    Institute of Scientific and Technical Information of China (English)

    常红; 李明雨

    2011-01-01

    In order to study the change of intermetallic compound (IMC) between solder joint and pad during electromigration, electromigration test was performed for Sn3.0Ag0.5Cu solder joint at 28 ℃ with a direct current of 6.5 A. The results show that, after 144 h electromigration, the IMC layer at anode thickens to 10.12 μm, while most part of the IMC layer at cathode thins to 0.86 μm and part of the Cu pad dissolves, however, an abnormal accumulation ofCu6Sn5 IMC is found at the fringe of cathode. The finite element analysis of temperature distribution in the solder joint indicates that the abnormal accumulation of IMC is due to that the thermomigration caused by temperature gradient dominates the partial migration process at cathode.%为了研究电迁移过程中焊点与焊盘界面金属问化合物(IMC)的变化,在28℃下,对无铅Sn3.0Ag0.5Cu焊点进行了6.5A直流电下的电迁移实验.结果发现,通电144h后,阳极侧IMC层变厚,平均达到10.12 μm;阴极侧IMC层大部分区域变薄至0.86μm,局部出现Cu焊盘的溶解消失,但在界面边缘处出现Cu3Sn5 IMC异常堆积现象.焊点温度分布的有限元模拟分析表明,阴极界面IMC的异常堆积是温度梯度引起的热迁移控制了阴极区局部迁移过程的结果.

  13. Characterization of Elastic-plastic Material Properties for IMC Layer of ENEPIG by Using Reverse Algorithm

    Science.gov (United States)

    Kim, Jong-Min; Lee, Hyun-Boo; Chang, Yoon-Suk; Choi, Jae-Boong; Kim, Young-Jin; Ji, Kum-Young

    2010-05-01

    Recently, the reliability assurance of lead-free solder to prevent environmental contamination is quite important issue for chip-scale packaging. Although lots of efforts have been devoted to the solder undergone drop, shear and creep loads, there was a little research on IMC due primarily to its thickness restriction and geometric irregularity. However, the IMC is known as the weakest layer governing failures of the solder joint. The present work is to characterize realistic material properties of the IMC for ENEPIG process. Lee's modified reverse algorithm was adopted to determine elastic-plastic stress-strain curve and so forth, after examining several methods, which requires inherently elastic data. In this context, a series of nano-indentation tests as well as corresponding simulations were carried out by changing indentation depths from 200 to 400 nm and strain rates from 0.05 to 0.10 1/s. It would be conclude that effect of strain rate is relatively small and IMC layer should be more than 5 times of indentation depth when using the recommended method, which are applicable to generate realistic material properties for further diverse structural integrity simulations.

  14. Sn-Ag-xCu-Bi-Ni/Cu焊点界面IMC演变%Evolution of the Interfacial IMC in Sn-Ag-xCu-Bi-Ni/Cu Solder Joints

    Institute of Scientific and Technical Information of China (English)

    孙凤莲; 汪洋; 刘洋; 王国军

    2012-01-01

    为了研究低银无铅焊点界面金属间化合物(IMC)的形成与演变,以低银无铅焊点Sn-Ag-xCu-Bi-Ni/Cu为研究对象,研究了钎料中Cu质量分数对界面IMC厚度、形貌和成分的影响.实验结果表明,随着钎料中Cu质量分数的增加,回流焊后焊点IMC层厚度变薄,IMC晶粒尺寸增大,IMC晶粒形貌由颗粒状转变为棱柱状以及鹅卵石状,同时界面IMC成分发生由(Cu,Ni)6Sn5向Cu6Sns的转变.高温时效后,界面IMC层厚度增长.当钎料中Cu质量分数超过1%时,时效后生成较厚的Cu3Sn化合物层,对焊点可靠性不利.钎料中Cu质量分数应控制在1%以下.%In order to study the formation and evolution of the intermetallic compounds (IMC) in low-Ag lead-free solder joints, the effect of Cu content on the thickness, morphology, and constituent of the interfacial IMC in Sn-Ag-xCu-Bi-Ni/Cu solder joints was investigated. Experimental results indicated that the thickness of IMC layer decreased but the grain size of which increased as the concentration of Cu increased in the solder alloys. Meanwhile , the appearance of IMC grains transformed from tiny grains to prisms and cobbles, and the constituent of IMC transformed from (Cu,Ni)6Sn5to Cu6Sn5. The thickness of IMC layer increased during high temperature storage ( HTS) aging. Thick Cu3Sn layer formed during aging when the Cu content was higher than 1% in the solder. Due to reliability concern, the content of Cu in the solder should be controlled less than 1 %.

  15. Miniaturization of Micro-Solder Bumps and Effect of IMC on Stress Distribution

    Science.gov (United States)

    Choudhury, Soud Farhan; Ladani, Leila

    2016-07-01

    As the joints become smaller in more advanced packages and devices, intermetallic (IMCs) volume ratio increases, which significantly impacts the overall mechanical behavior of joints. The existence of only a few grains of Sn (Tin) and IMC materials results in anisotropic elastic and plastic behavior which is not detectable using conventional finite element (FE) simulation with average properties for polycrystalline material. In this study, crystal plasticity finite element (CPFE) simulation is used to model the whole joint including copper, Sn solder and Cu6Sn5 IMC material. Experimental lap-shear test results for solder joints from the literature were used to validate the models. A comparative analysis between traditional FE, CPFE and experiments was conducted. The CPFE model was able to correlate the experiments more closely compared to traditional FE analysis because of its ability to capture micro-mechanical anisotropic behavior. Further analysis was conducted to evaluate the effect of IMC thickness on stress distribution in micro-bumps using a systematic numerical experiment with IMC thickness ranging from 0% to 80%. The analysis was conducted on micro-bumps with single crystal Sn and bicrystal Sn. The overall stress distribution and shear deformation changes as the IMC thickness increases. The model with higher IMC thickness shows a stiffer shear response, and provides a higher shear yield strength.

  16. Effect of La addition on the IMC of SnAgCu/Cu and Ni%La对SnAgCu/Cu及Ni界面金属间化合物的影响

    Institute of Scientific and Technical Information of China (English)

    王佳; 王丽凤; 刘学

    2011-01-01

    利用扫描电镜、能谱分析仪对Sn0.3Ag0.7Cu-xLa/Cu(x=0~0.25)和Ni界面金属间化合物(IMC)形成及长大规律进行了研究.结果表明:微量La的添加使钎焊与时效后焊点/Cu界面生成的CuSn晶粒明显细化,当X超过0.10时,CuSn晶粒的上方出现大量的粒状AgSn,晶粒表面粗化并出现孔洞.X为0.07的焊点/Ni的IMC厚度变化在时效过程中比较稳定,且超过300h时效后,其IMC厚度最小,因此,La的最佳质量分数应为0.07%.%The formation and growth of intermetallic compounds (IMC) for Sn0.3Ag0.7Cu-xLa/Cu (x = 0-0.25) and Ni were studied with the scanning electron microscope and the energy dispersive X-ray detector. The results indicate that the grain size of Cu6Sn5 in the soldering point/Cu interface is obviously refined with La addition after reflowing and aging.When x surpasses 0.10, numerous grains of Ag3Sn appear on the top of Cu6Sn5 grain, and the surface of Cu6Sn5 becomes coarsing and emerges many. holes. When x is 0.07, the thickness of IMC changes relatively stable with increment of the aging time and is minimum after 300 h aging. The optimum addition of w(La) is 0.07%.

  17. DIFFUSION-INDUCED STRESS IN THE INTERMETALLIC COMPOUND LAYER OF SOLDER JOINTS%焊锡接点IMC层的扩散应力

    Institute of Scientific and Technical Information of China (English)

    秦飞; 安彤; 夏国峰

    2012-01-01

    钎焊过程中在焊锡接点中形成的金属间化合物(IMC)对焊锡接点可靠性具有重要影响.在原子扩散效应下,回流焊和等温时效过程中IMC层的生长会在其内部产生应力,其微结构也发生变化,致使IMC层和整个焊锡接点的力学性能下降.论文基于扩散反应机制,研究了由于原子扩散产生的IMC层的扩散应力.首先建立了描述焊锡接点IMC层生长早期微结构特征的2界面(Cu/Cu6 Sn5/Solder)分析模型,然后运用Laplace变换法求解扩散方程得到了Cu原了在IMC层中的浓度分布;采用把原子扩散作用转换为体应变方法,计算了IMC层在形成和生长过程中应力的解析解.结果表明:IMC层中的扩散应力为压应力,最大值位于Cu/IMC界面处,大小与扩散原子浓度密切相关;随着时效时间的增加,扩散应力增大,但最终趋于稳定并沿IMC厚度方向线性变化.%Intermetallic compound (IMC) layers formed during soldering processes significantly affect the reliability of solder joints. The atomic diffusion effect during reflow and isothermal aging leads to growth and morphological evolution of IMC layers.and stress is developed in the IMC layers. The changed microstructure and the stress in the IMC layer result in degradation of mechanical performance of solder joints. Based on the mechanism of atomic diffusion-reaction, the diffusion induced stress during the growth of the IMC layer is investigated. An analytic model with two interfaces(Cu/Cu6Sn3/Solder)at the early stages of IMC formation is proposed,and then the copper concentration distribution in the IMC layer is calculated using the Laplace transformation method. Diffusion-induced stresses are obtained analytically by transforming atomic diffusion effects into bulk strain. The results show that the diffusion-induced stress is compressive,and it reaches its peak at the Cu/Cu6Sn5 interface. The diffusion induced stress increases with the increase of the isothermal

  18. Investigation on the Microstructure, Interfacial IMC Layer, and Mechanical Properties of Cu/Sn-0.7Cu- xNi/Cu Solder Joints

    Science.gov (United States)

    Yang, Li; Ge, Jinguo; Zhang, Yaocheng; Dai, Jun; Liu, Haixiang; Xiang, Jicen

    2016-07-01

    Sn-0.7Cu- xNi composite solder has been fabricated via mechanical mixing of different weight percentages of Ni particles with Sn-0.7Cu solder paste, and the effect of the Ni concentration on the microstructure, wettability, and tensile properties of Cu/Sn-0.7Cu- xNi/Cu solder joints investigated. The results show that refined dot-shaped particles of intermetallic compounds (IMCs) are uniformly dispersed in a primary β-Sn matrix in the Cu/Sn-0.7Cu-(0.05-0.1)Ni/Cu solder joints. The interfacial IMC layer thickness increased slightly when adding Ni content to 0.05 wt.%, then rapidly when further increasing the Ni concentration to 0.4 wt.%. Excellent wettability with bright appearance was obtained for the Sn-0.7Cu-0.05Ni solder due to diminished interfacial tension. The tensile properties improved after adding Ni content to 0.05 wt.% due to the presence of the refined dot-like IMC particles, in agreement with theoretical predictions based on the combination of dispersion and grain-refinement strengthening mechanisms. Refined microstructure and enhanced mechanical properties were obtained for the Cu/Sn-0.7Cu-0.05Ni/Cu solder joint.

  19. Effects of post-reflow cooling rate and thermal aging on growth behavior of interfacial intermetallic compound between SAC305 solder and Cu substrate

    Science.gov (United States)

    Hu, Xiaowu; Xu, Tao; Jiang, Xiongxin; Li, Yulong; Liu, Yi; Min, Zhixian

    2016-04-01

    The interfacial reactions between Cu and Sn3Ag0.5Cu (SAC305) solder reflowed under various cooling rates were investigated. It is found that the cooling rate is an important parameter in solder reflow process because it influences not only microstructure of solder alloy but also the morphology and growth of intermetallic compounds (IMCs) formed between solder and Cu substrate. The experimental results indicate that only scallop-like Cu6Sn5 IMC layer is observed between solder and Cu substrate in case of water cooling and air cooling, while bilayer composed of scallop-like Cu6Sn5 and thin layer-like Cu3Sn is detected under furnace cooling due to sufficient reaction time to form Cu3Sn between Cu6Sn5 IMC and Cu substrate which resulted from slow cooling rate. Samples with different reflow cooling rates were further thermal-aged at 423 K. And it is found that the thickness of IMC increases linearly with square root of aging time. The growth constants of interfacial IMC layer during aging were obtained and compared for different cooling rates, indicating that the IMC layer thickness increased faster in samples under low cooling rate than in the high cooling rate under the same aging condition. The long prismatic grains were formed on the existing interfacial Cu6Sn5 grains to extrude deeply into solder matrix with lower cooling rate and long-term aging, and the Cu6Sn5 grains coarsened linearly with cubic root of aging time.

  20. Pathway analysis of IMC

    DEFF Research Database (Denmark)

    Skrypnyuk, Nataliya; Nielson, Flemming; Pilegaard, Henrik

    2009-01-01

    We present the ongoing work on the pathway analysis of a stochastic calculus. Firstly we present a particular stochastic calculus that we have chosen for our modeling - the Interactive Markov Chains calculus, IMC for short. After that we specify a few restrictions that we have introduced into the......We present the ongoing work on the pathway analysis of a stochastic calculus. Firstly we present a particular stochastic calculus that we have chosen for our modeling - the Interactive Markov Chains calculus, IMC for short. After that we specify a few restrictions that we have introduced...

  1. PDSS/IMC requirements and functional specifications

    Science.gov (United States)

    1983-01-01

    The system (software and hardware) requirements for the Payload Development Support System (PDSS)/Image Motion Compensator (IMC) are provided. The PDSS/IMC system provides the capability for performing Image Motion Compensator Electronics (IMCE) flight software test, checkout, and verification and provides the capability for monitoring the IMC flight computer system during qualification testing for fault detection and fault isolation.

  2. First-Principles Study of Thermodynamical and Elastic Properties of η'-(Cu,Co)6Sn5 Ternary Alloys

    Science.gov (United States)

    Zhang, Xuechao; Zhao, Xiuchen; Zheng, Bing; Liu, Ying; Cheng, Jingwei; Li, Hong

    2016-10-01

    First-principles calculations were made to investigate the formation energy and elastic properties of η'-Cu6Sn5-based intermetallic compounds (IMCs) with different amounts of Co substitutional atom concentrations. The possible Co substitutional sites in η'-Cu6Sn5 structures are examined. The formation energy of substitutional Co in η'-Cu6Sn5 is reduced with increasing Co concentration. The effect of Co on the elastic modulus and ductility of η'-Cu6Sn5 dramatically increased the elastic properties of Cu-Sn IMCs in the range 0-27.27 at.%. Cu4Co2Sn5 has the highest Young's modulus, bulk modulus and shear modulus with a maximum Poisson's ratio of 0.32 with 18.18 at.% Co concentration. Ductility for these compounds is further analyzed by calculating the ratio of B/ G and Cauchy's stress ( C 12 - C 44) and the results indicate that η'-Cu6Sn5 with Co substitutions should have a better ductility than the pure η'-Cu6Sn5 structure. The electronic structures of Co-substituted η'-Cu6Sn5 are analyzed and the increasing hybridization between Co- d and Sn- p accounts for the improved phase stability and elastic modulus of η'-Cu6Sn5 with Co addition up to 18.18 at.%.

  3. IMC/RMC Network Professional Film Collection.

    Science.gov (United States)

    New York State Education Dept., Albany. Special Education Instructional Materials Center.

    The compilation is a comprehensive listing of films available from the centers in the Instructional Materials Centers/Regional Media Centers (IMC/RMC) Network. Each IMC/RMC location is given a numerical code in a preliminary listing. These numerical codes are used within the film listing, which is arranged alphabetically according to film titles,…

  4. From the editor - about the IMC Proceedings

    Science.gov (United States)

    Roggemans, P.

    2016-01-01

    At the occasion of the 25th IMC in Roden, the Netherlands in 2006, the history of the IMCs was put in the spotlight with a dedicated presentation. Meanwhile we are 10 years later and many new faces appeared at the conference as regular participants. An update on the history of the IMCs is given. One of the first time participants at the 35th International Meteor Conference was the 1000nd officially registered participant according to the final effective participants' lists since 1979. In total 1033 different individuals have participated at one or more IMCs since 1979. The 35th IMC broke a few records: the largest total number of participants, the largest number of presentations, both talks and posters and the thickest IMC Proceedings ever. The International Meteor Conference got a splendid reputation worldwide as unique event among all international meetings of amateur astronomers. As far as the author is aware of, there is no other amateur conference in any astronomy domain comparable to the IMC. Some statistics about the conference and its history are presented.

  5. Effect of adding Ce on interfacial reactions between Sn-3.0Ag-0.5Cu solder and Cu substrate

    Institute of Scientific and Technical Information of China (English)

    LU Bin; LI Hui; WANG Juan-hui; ZHU Hua-wei; JIAO Xian-he

    2008-01-01

    The formation and the growth of Cu-Sn intermetallic compound (IMC) layer at the interface between Sn-3.0Ag-0.5Cu-xCe solder and Cu substrate during soldering and aging were studied. The results show that Cu6Sn5 IMC is observed at the interface between solder and Cu substrate in all conditions. After aging for 120h, the Cu3Sn IMC is then obtained. With increasing aging time, the scalloped Cu6Sn5 structure changes to a plate structure. The Cu3Sn film always forms with a relatively planar interface. By adding a small amount of the rare earth element Ce (only 0.1%, mass fraction) into the Sn-3.0Ago0.5Cu solder alloy, the growth rate of the Cu-Sn IMC at the interface of solder alloy system is decreased. When the time exponent is approximately 0.5, the growth of the IMC layer is mainly controlled by a diffusion over the studied time range.

  6. PDSS/IMC CIS user's guide

    Science.gov (United States)

    1984-01-01

    The Spacelab Payload Development Support System PDSS Image Motion Compensator (IMC) computer interface simulation (CIS) user's manual is given. The software provides a real time interface simulation for the following IMC subsystems: the Dry Rotor Reference Unit, the Advanced Star/Target Reference Optical sensor, the Ultra Violet imaging telescope, the Wisconson Ultraviolet Photopolarimetry Experiment, the Cruciform Power distributor, and the Spacelab Experiment Computer Operating System.

  7. Formative Assessment in the High School IMC

    Science.gov (United States)

    Edwards, Valerie A.

    2007-01-01

    In this article, the author discusses how she uses formative assessments of information literacy skills in the high school IMC. As a result of informal observation and conversations with individual students--a form of formative assessment itself--the author learned that students were not using indexes to locate relevant information in nonfiction…

  8. PDSS/IMC qualification test software acceptance procedures

    Science.gov (United States)

    1984-01-01

    Tests to be performed for qualifying the payload development support system image motion compensator (IMC) are identified. The performance of these tests will verify the IMC interfaces and thereby verify the qualification test software.

  9. A reliability study on tin based lead free micro joint including intermetallic and void evolution

    Science.gov (United States)

    Feyissa, Frezer Assefa

    In microelectronics soldering to Cu pad lead to formation of two intermetallic structures in the solder -pad interface. The growth of these layers is accompanied by microscopic voids that usually cause reliability concern in the industry. Therefore it is important to understand factors that contribute for the growth of IMC using various combination of reflow time, Sn thickness and aging temperature. Systematic study was conducted on Cu-Sn system to investigate the formation and growth of intermetallic compound (IMC) as well as voiding evolution for different solder thicknesses. The growth of the Cu6Sn5 IMC layer was found to be increasing as the Sn thicknesses increase after reflow while the Cu3Sn layer were decreasing under same conditions. Also after reflow and aging more voiding were shown to occur in the thin solder than thicker one.

  10. Microinjection of limonene into caudate nucleus inhibits IMC of rats

    Institute of Scientific and Technical Information of China (English)

    Hong Guo; Xin Yi Zhu; Yi Quan Wei; De Zhi Yang

    2000-01-01

    AIM We have discovered that Limonene modulates interdigestive myoelectrical complexes (IMCs) ofgastrointestinal tract in rats. In this research we will elucidate weather limonene affects acetylcholine M-receptor in caudate nucleus.METHODS Changes of IMCs were studied after limonene and/or atropine were microinjected into caudatenucleus. IMCs were recorded by a RM-6200 four-channel recorder and then delivered to Maclab and PowerMacintosh.RESULTS The active phases of IMCs occupied about 40% of total cycle in average. After microinjection oflimonene into caudate nucleus, the active phases were significantly shortened, while the cycle time of IMCswere not changed significantly. The inhibitory effects of limonene were abolished by pretreatment withatropine, whilst the atropine has no effect on IMCs.CONCLUSION It is suggested that limonene inhabits the gastrointestinal IMCs by affecting M-receptor incaudate nucleus.

  11. Summer Project on Exponential Convergence for IMC

    Energy Technology Data Exchange (ETDEWEB)

    Gentile, N [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-05-23

    I want to look at modifying the Morel and Bolding algorithm in two ways. One is to remove the need to represent the intensity in a deterministic form and for a deterministic representation of a transport operator. The second is to look at representing the moments of the source with a simpler form that doesn’t require as many terms. Morel and Bolding also didn’t include scattering in their stuff. IMC has a lot of scattering occurring because of the effective scatters. I think that scattering can be added to the method, but I think that will require more than a summer’s worth of work. So we’ll just ignore scattering, and just look at problems with a huge cv so that there is no effective scattering.

  12. Perpendicular Growth Characteristics of Cu-Sn Intermetallic Compounds at the Surface of 99Sn-1Cu/Cu Solder Interconnects

    Science.gov (United States)

    Chen, Zhiwen; Liu, Changqing; Wu, Yiping; An, Bing

    2015-12-01

    The growth of intermetallic compounds (IMCs) on the free surface of 99Sn-1Cu solder joints perpendicular to the interdiffusion direction has been investigated in this work. The specimens were specifically designed and polished to reveal a flat free surface at the solder/Cu interface for investigation. After aging at 175°C for progressively increased durations, the height of the perpendicular IMCs was examined and found to follow a parabolic law with aging duration that could be expressed as y = 0.11√ t, where t is the aging duration in hours and y is the height of the perpendicular IMCs in μm. For comparison, the planar growth of IMCs along the interdiffusion direction was also investigated in 99Sn-1Cu/Cu solder joints. After prolonged aging at 175°C, the thickness of the planar interfacial IMC layers also increased parabolically with aging duration and could be expressed as h_{{IMC}} = 0.27√ t + 4.6, where h is the thickness in μm and t is the time in hours. It was found that both the planar and perpendicular growth of the IMCs were diffusion-controlled processes, but the perpendicular growth of the IMCs was much slower than their planar growth due to the longer diffusion distance. It is proposed that Cu3Sn forms prior to the formation of Cu6Sn5 in the perpendicular IMCs, being the reverse order compared with the planar IMC growth.

  13. Reaction of Liquid Sn-Ag-Cu-Ce Solders with Solid Copper

    Science.gov (United States)

    Chriaštel'Ová, J.; Rízeková Trnková, L.; Pocisková Dimová, K.; Ožvold, M.

    2011-09-01

    Small amounts of the rare-earth element Ce were added to the Sn-rich lead-free eutectic solders Sn-3.5Ag-0.7Cu, Sn-0.7Cu, and Sn-3.5Ag to improve their properties. The microstructures of the solders without Ce and with different amounts (0.1 wt.%, 0.2 wt.%, and 0.5 wt.%) of Ce were compared. The microstructure of the solders became finer with increasing Ce content. Deviation from this rule was observed for the Sn-Ag-Cu solder with 0.2 wt.% Ce, and for the Sn-0.7Cu eutectic alloy, which showed the finest microstructure without Ce. The melting temperatures of the solders were not affected. The morphology of intermetallic compounds (IMC) formed at the interface between the liquid solders and a Cu substrate at temperatures about 40°C above the melting point of the solder for dipping times from 2 s to 256 s was studied for the basic solder and for solder with 0.5 wt.% Ce addition. The morphology of the Cu6Sn5 IMC layer developed at the interface between the solders and the substrate exhibited the typical scallop-type shape without significant difference between solders with and without Ce for the shortest dipping time. Addition of Ce decreased the thickness of the Cu6Sn5 IMC layer only at the Cu/Sn-Ag-Cu solder interface for the 2-s dipping. A different morphology of the IMC layer was observed for the 256-s dipping time: The layers were less continuous and exhibited a broken relief. Massive scallops were not observed. For longer dipping times, Cu3Sn IMC layers located near the Cu substrate were also observed.

  14. Interfacial Reactions and Joint Strengths of Sn- xZn Solders with Immersion Ag UBM

    Science.gov (United States)

    Jee, Y. K.; Yu, Jin

    2010-10-01

    The solder joint microstructures of immersion Ag with Sn- xZn ( x = 0 wt.%, 1 wt.%, 5 wt.%, and 9 wt.%) solders were analyzed and correlated with their drop impact reliability. Addition of 1 wt.% Zn to Sn did not change the interface microstructure and was only marginally effective. In comparison, the addition of 5 wt.% or 9 wt.% Zn formed layers of AgZn3/Ag5Zn8 at the solder joint interface, which increased drop reliability significantly. Under extensive aging, Ag-Zn intermetallic compounds (IMCs) transformed into Cu5Zn8 and Ag3Sn, and the drop impact resistance at the solder joints deteriorated up to a point. The beneficial role of Zn on immersion Ag pads was ascribed to the formation of Ag-Zn IMC layers, which were fairly resistant to the drop impact, and to the suppression of the brittle Cu6Sn5 phase at the joint interface.

  15. Integrated Marketing Communications (IMC di PT Halo Rumah Bernyanyi

    Directory of Open Access Journals (Sweden)

    Rebekka Rismayanti

    2017-01-01

    Full Text Available Abstract: This research aims to describe the effectiveness of Integrated Marketing Communication (IMC in PT Halo Rumah Bernyanyi which, from the perspective of marketing strategy, could be studied by analyzing the segmentation, targeting, and positioning. Using case-study method with in-depth interview, the result shows that the implementation of IMC at PT Halo Rumah Bernyayi is arranged in one single strategy and tend to neglect the complexities of running multi-brand family karaoke-house. This considers as ineffective because it leads to “cannibalization” among brands, especially when costumer’s targetting is overlooked before drafting the IMC plan. Keywords: Business, Integrated Marketing Communication, Marketing   Abstrak: Penelitian ini bertujuan untuk mendeskripsikan efektivitas penerapan Integrated Marketing Communications (IMC yang dilihat dari aspek segmentation, targeting dan positioning. Metode penelitian adalah studi kasus dengan menggunakan wawancara mendalam. Hasil penelitian menunjukkan bahwa penerapan IMC di PT Halo Rumah Bernyanyi dibuat dalam satu strategi dan tidak memerhatikan kompleksitas dari aspek segmentation, targeting dan positioning sebagai pedoman dasar. Langkah tersebut dinilai tidak efektif karena dapat mengakibatkan “kanibalisasi” antar brand, terlebih jika perhatian terhadap target konsumen diabaikan sebelum menyusun perencanaan IMC. Kata Kunci: Bisnis, Integrated Marketing Communications, Pemasaran

  16. Characterization and modeling of microstructural evolution of near-eutectic tin-silver-copper solder joints

    Science.gov (United States)

    Zbrzezny, Adam R.

    Near-eutectic Sn-Ag-Cu (SAC) solders are currently considered as major lead-free replacement candidates for Sn-Pb eutectic alloys in microelectronics applications. In this thesis, the microstructural thermal stability including recrystallization, grain growth behavior, Pb and Au contamination effects and interaction of the SAC solder with Cu and Ni substrates were investigated. The true eutectic composition of the Sn-Ag-Cu alloy was verified to be Sn3.5Ag0.9Cu wt.%, and the eutectic melting temperature was determined to be 217.4 +/- 0.8°C. The system was classified as belonging to faceting (Cu6Sn5)-faceting (Ag3Sn)-nonfaceting (Sn matrix) ternary eutectic. The most significant consequence of Pb contamination was the formation of a quaternary eutectic phase (Sn-Ag-Cu-Pb) with a melting point at 176°C. Similarly, the presence of gold in the SAC alloy led to a development of a new quaternary phase (Sn-Ag-Cu-Au) melting at 204°C. Prolonged aging of SAC-4 wt.% Au on nickel resulted in the deposition of a new, previously unreported, intermetallic (IMC) layer, ((Au1-xCUx)6Sn 5, 15 wt.% of Au) on top of the existing (Cu1-yNi y)6Sn5 layer. The interfacial products that formed during soldering to copper were Cu6Sn5 and Cu3Sn. Soldering to nickel resulted in the formation of one layer, (Cu1-yNiy) 6Sn5, which was different from the expected Ni3Sn 4 layer. A small copper content in the SAC solder (0.7 wt.%) was sufficient to promote this thermodynamic shift. Intermetallic growth on Cu during solid state aging was established to be bulk diffusion controlled. The IMC layers in the SAC system grew at a slower rate than in the Sn-Pb system. It was found that the reliability of SAC solder joints on copper was considerably better than on nickel due to copper enrichment during reflow and subsequent Cu6Sn5 intermetallic precipitation. Enhanced copper and silver diffusion followed by tin recrystallization and grain growth, cavity nucleation and subsequent micro-crack linkage formed

  17. Electromigration-induced cracks in Cu/Sn3.5Ag/Cu solder reaction couple at room temperature

    Science.gov (United States)

    Hongwen, He; Guangchen, Xu; Fu, Guo

    2009-03-01

    Electromigration (EM) behavior of Cu/Sn3.5Ag/Cu solder reaction couple was investigated with a high current density of 5 × 103 A/cm2 at room temperature. One dimensional structure, copper wire/solder ball/copper wire SRC was designed and fabricated to dissipate the Joule heating induced by the current flow. In addition, thermomigration effect was excluded due to the symmetrical structure of the SRC. The experimental results indicated that micro-cracks initially appeared near the cathode interface between solder matrix and copper substrate after 474 h current stressing. With current stressing time increased, the cracks propagated and extended along the cathode interface. It should be noted that the continuous Cu6Sn5 intermetallic compounds (IMCs) layer both at the anode and at the cathode remained their sizes. Interestingly, tiny cracks appeared at the root of some long column-type Cu6Sn5 at the cathode interface due to the thermal stress.

  18. The IMC-IMC Cascade Control for Time-delay Systems%时滞系统的IMC-IMC串级控制

    Institute of Scientific and Technical Information of China (English)

    王娟; 赵曜; 吴亚峰

    2007-01-01

    针对一类含大时滞且对抗扰性有严格要求的系统,结合内模控制(IMC)对大时滞系统的控制优越性和串级控制良好的抗扰性,提出IMC-IMC串级控制方法,将两个IMC结构引入串级控制系统中,主要扰动包含在副回路,两个内模控制器分别调节系统的跟踪和抗扰性能.理论分析和仿真结果表明,该方法对于大时滞系统同时具备良好的跟踪和抗扰性能.

  19. Procedures Handbook for Elementary School IMC Clerks. Revised.

    Science.gov (United States)

    Allen, Christine

    This training manual describes and explains the variety of tasks performed by library clerks in the Riverside (California) Unified School District's elementary school instructional media centers (IMCs). It is noted that the job responsibilities of these clerks fall into four areas with specific duties relating to each: maintenance of the…

  20. The Impact of IMC on Advertising and Public Relations Education.

    Science.gov (United States)

    Griffin, W. Glenn; Pasadeos, Yorgo

    1998-01-01

    Surveys advertising and public relations faculty members with regard to IMC (Integrated Marketing Communications) and its impact on current curricula. Finds (1) areas of discontent with current course curricula; (2) evidence of "separate agendas" between advertising and public relations educators on this issue; and (3) evidence of a generation gap…

  1. Learning Through Media; An IMC Handbook for Chelmsford Teachers.

    Science.gov (United States)

    Morrow, James; Wallace, Daniel

    This handbook is designed to provide basic information that is necessary to use the Chelmsford School System's Instructional Media Center (IMC). It defines six different media (print, sound, television, photography, movies and design) and suggests a series of separate classroom production activities in each. An emphasis is given to the ways in…

  2. Summary of the Open Session at the IMC 2016

    Science.gov (United States)

    Verbeeck, C.; Argo, M.; Brown, P.; Molau, S.; Rendtel, J.; Martínez Picar, A.

    2016-01-01

    The Open Session at the IMC 2016 took place on Friday, June 3rd 2016 evening (21:30-22:30) and was intended to accommodate beginners' questions about meteor astronomy. Megan Argo moderated a panel of experts, consisting of Peter Brown, Sirko Molau, Jürgen Rendtel, and Antonio Martínez Picar.

  3. IMC based robust PID controller tuning for disturbance rejection

    Institute of Scientific and Technical Information of China (English)

    Mohammad Shamsuzzoha

    2016-01-01

    It is well-known that the IMC-PID controller tuning gives fast and improved set point response but slow disturbance rejection. A modification has been proposed in IMC-PID tuning rule for the improved disturbance rejection. For the modified IMC-PID tuning rule, a method has been developed to obtain the IMC-PID setting in closed-loop mode without acquiring detailed information of the process. The proposed method is based on the closed-loop step set point experiment using a proportional only controller with gainKc0. It is the direct approach to find the PID controller setting similar to classical Ziegler-Nichols closed-loop method. Based on simulations of a wide range of first-order with delay processes, a simple correlation has been derived to obtain the modified IMC-PID controller settings from closed-loop experiment. In this method, controller gain is a function of the overshoot obtained in the closed loop set point experiment. The integral and derivative time is mainly a function of the time to reach the first peak (overshoot). Simulation has been conducted for the broad class of processes and the controllers were tuned to have the same degree of robustness by measuring the maximum sensitivity, Ms, in order to obtain a reasonable comparison. The PID controller settings obtained in the proposed tuning method show better performance and robustness with other two-step tuning methods for the broad class of processes. It has also been applied to temperature control loop in distillation column model. The result has been compared to the open loop tuning method where it gives robust and fast response.

  4. PID Controller Design Based on the Time Domain Information of Robust IMC Controller Using Maximum Sensitivity

    Institute of Scientific and Technical Information of China (English)

    JIN Qibing; LIU Qie; WANG Qi; TIAN Yuqi; WANG Yuanfei

    2013-01-01

    The IMC (Internal Model Control) controller based on robust tuning can improve the robustness and dynamic performance of the system.In this paper,the robustness degree of the control system is investigated based on Maximum Sensitivity (Ms) in depth.And the analytical relationship is obtained between the robustness specification and controller parameters,which gives a clear design criterion to robust IMC controller.Moreover,a novel and simple IMC-PID (Proportional-Integral-Derivative) tuning method is proposed by converting the IMC controller to PID form in terms of the time domain rather than the frequency domain adopted in some conventional IMC-based methods.Hence,the presented IMC-PID gives a good performance with a specific robustness degree.The new IMC-PID method is compared with other classical IMC-PID rules,showing the flexibility and feasibility for a wide range of plants.

  5. Mechanical Characterization of Lead-Free Sn-Ag-Cu Solder Joints by High-Temperature Nanoindentation

    OpenAIRE

    Lotfian, S.; Molina Aldareguía, Jon M.; Yazzie, K. E.; Llorca Martinez, Francisco Javier; Chawla, N

    2013-01-01

    The reliability of Pb-free solder joints is controlled by their microstructural constituents. Therefore, knowledge of the solder microconstituents’ mechanical properties as a function of temperature is required. Sn-Ag-Cu lead-free solder alloy contains three phases: a Sn-rich phase, and the intermetallic compounds (IMCs) Cu6Sn5 and Ag3Sn. Typically, the Sn-rich phase is surrounded by a eutectic mixture of β-Sn, Cu6Sn5, and Ag3Sn. In this paper, we report on the Young’s modulus and hardness of...

  6. Limitaciones del IMC como indicador exclusivo de estado nutricional

    Directory of Open Access Journals (Sweden)

    Moreno Romero, Susana

    2007-01-01

    Full Text Available El presente trabajo tiene como objetivo determinar el potencial diagnóstico y las limitaciones del uso del Índice de Masa Corporal como único indicador del estado nutricional. Para ello se analizó una muestra constituida por 2155 sujetos de ambos sexos, con edades comprendidas entre los 6 y 18 años y pertenecientes a tres poblaciones jujeñas que difieren en ubicación altitudinal y nivel socieconómico (NSE: 1. Susques, localidad rural situada a 3675 m.s.n.m; 2. Alto Comedero, barrio periférico de San Salvador de Jujuy (1250 m.s.n.m. de NSE bajo; y 3. José Hernández, muestra representativa del estrato SE elevado de la misma capital. Se tomaron las medidas directas de talla, peso, perímetro braquial y pliegues de grasa subcutánea tricipital y subescapular, entre otras. A partir de éstas, se calculó el IMC y las áreas tisulares del brazo. Se establecieron las categorías nutricionales en función de los percentilos establecidos por el NHANES I y II para la talla, IMC, área magra y grasa del brazo y pliegues tricipital y subescapular. Al comparar los resultados obtenidos para cada variable se comprueba como el uso exclusivo del IMC enmascara importantes patologías nutricionales, tanto por defecto como por exceso.

  7. Development of Solar Tracking System Using Imc-Pid Controller

    Directory of Open Access Journals (Sweden)

    Bamigboye O. Oladayo

    2016-06-01

    Full Text Available In the past, solar cells are hooked with fixed elevating angles, and it does not track the sun. Therefore the efficiency of the power generation is low. A solar panel receives the most sunlight when it is perpendicular to the sun’s rays, but the sunlight direction changes regularly with changing seasons and weather. There is therefore the need to track the solar panel to increase its efficiency. The stability and improved speed of response can only be achieved with appropriate controller to take care of external disturbances and design uncertainty associated with a conventional controller. The IMC controller would be used to allow good tracking ability and good load disturbance rejection Unconventional controller like fuzzy logic can be used to tune the PID controller andthe result compared with using a conventional controller like ZN. The internal model control based proportional integral derivative design procedure can be implemented in industrial processes using existing proportional integral derivative control equipment. Modeling of a dual axis solar tracker. An IMC-PID controller was developed for a dual axis solar tracker. The result of this work showed that the IMC-PID controller provided an efficient and commendable improvement in the relative stability, disturbance attenuation, set point tracking and an improved speed of response for the system

  8. Investigation of the Phase Equilibria of Sn-Cu-Au Ternary and Ag-Sn-Cu-Au Quaternary Systems and Interfacial Reactions in Sn-Cu/Au Couples

    Science.gov (United States)

    Yen, Yee-Wen; Jao, Chien-Chung; Hsiao, Hsien-Ming; Lin, Chung-Yung; Lee, Chiapyng

    2007-02-01

    The phase equilibria of the Sn-Cu-Au ternary, Ag-Sn-Cu-Au quaternary systems and interfacial reactions between Sn-Cu alloys and Au were experimentally investigated at specific temperatures in this study. The experimental results indicated that there existed three ternary intermetallic compounds (IMCs) and a complete solid solubility between AuSn and Cu6Sn5 phases in the Sn-Cu-Au ternary system at 200°C. No quaternary IMC was found in the isoplethal section of the Ag-Sn-Cu-Au quaternary system. Three IMCs, AuSn, AuSn2, and AuSn4, were found in all couples. The same three IMCs and (Au,Cu)Sn/(Cu,Au)6Sn5 phases were found in all Sn-Cu/Au couples. The thickness of these reaction layers increased with increasing temperature and time. The mechanism of IMC growth can be described by using the parabolic law. In addition, when the reaction time was extended and the Cu content of the alloy was increased, the AuSn4 phase disappeared gradually. The (Au, Cu)Sn and (Cu,Au)6Sn5 layers played roles as diffusion barriers against Sn in Sn-Cu/Au reaction couple systems.

  9. Size effects in tin-based lead-free solder joints: Kinetics of bond formation and mechanical characteristics

    Science.gov (United States)

    Abdelhadi, Ousama Mohamed Omer

    Continuous miniaturization of microelectronic interconnects demands smaller joints with comparable microstructural and structural sizes. As the size of joints become smaller, the volume of intermetallics (IMCs) becomes comparable with the joint size. As a result, the kinetics of bond formation changes and the types and thicknesses of IMC phases that form within the constrained region of the bond varies. This dissertation focuses on investigating combination effects of process parameters and size on kinetics of bond formation, resulting microstructure and the mechanical properties of joints that are formed under structurally constrained conditions. An experiment is designed where several process parameters such as time of bonding, temperature, and pressure, and bond thickness as structural chracteristic, are varied at multiple levels. The experiment is then implemented on the process. Scanning electron microscope (SEM) is then utilized to determine the bond thickness, IMC phases and their thicknesses, and morphology of the bonds. Electron backscatter diffraction (EBSD) is used to determine the grain size in different regions, including the bulk solder, and different IMC phases. Physics-based analytical models have been developed for growth kinetics of IMC compounds and are verified using the experimental results. Nanoindentation is used to determine the mechanical behavior of IMC phases in joints in different scales. Four-point bending notched multilayer specimen and four-point bending technique were used to determine fracture toughness of the bonds containing IMCs. Analytical modeling of peeling and shear stresses and fracture toughness in tri-layer four-point bend specimen containing intermetallic layer was developed and was verified and validated using finite element simulation and experimental results. The experiment is used in conjunction with the model to calculate and verify the fracture toughness of Cu6Sn5 IMC materials. As expected two different IMC phases

  10. Alloying Effects on the Phase Stability and Mechanical Properties of Doped Cu-Sn IMCs: A First-Principle Study

    Science.gov (United States)

    Zhang, Yong; Yuan, Ding-Wang; Chen, Jiang-Hua; Zeng, Guang; Fan, Tou-Wen; Liu, Zi-Ran; Wu, Cui-Lan; Liu, Ling-Hong

    2016-08-01

    Cu-Sn phases are important intermetallic compounds formed at the interface between solder and substrate in the soldering process. They exist in several crystal structures ( η', η, η 1 and η 2, etc.). The solid-state phase transformation that occurs among Cu-Sn intermetallic compounds is a crucial issue for industry applications, because the associated volume change inevitably leads to microstructural instability. Generally, four alloying elements, i.e., Ni, Au, Zn, and indium (In), are used as alloying elements to stabilize the high temperature hexagonal η-phase. However, the physical mechanism of this stabilization effect, especially on the high temperature η 1 and η 2 phases, is still unclear. In the present study, first-principle calculations were performed to study the stability and mechanical properties of Cu5Sn4 ( η 1 and η 2) and Cu6Sn5 ( η') when doped with Ni, Au, Zn, and indium alloying elements. It is shown that their phase stability and mechanical properties could be enhanced by these elements in some circumstances. Ni-doping can significantly enhance both the stability and the mechanical properties of the three phases, whereas Zn-doping exhibits a significant effect on that of the η 2 phase.

  11. The influence of heat treatment on properties of lead-free solders

    Directory of Open Access Journals (Sweden)

    Lýdia Trnková Rízeková

    2015-02-01

    Full Text Available The article is focused on the analysis of degradation of properties of two eutectic lead-free solders SnCu0.7 and SnAg3.5Cu0.7. The microstructures of the intermetallic compound (IMC layers at the copper substrate - solder interface were examined before and after heat treatment at 150°C for 50, 200, 500 and 1000 hours. The thickness of IMC layers of the Cu6Sn5 phase was growing with the increasing time of annealing and shown the typical scallops. For the heat treatment times of 200 hours and longer, the Cu3Sn IMC layers located near the Cu substrate were also observed. The experiments showed there is a link between the thickness of IMC layers and decrease of the shear strength of solder joints. In general, the joints made of the ternary solder showed higher shear strength before and after heat treatment in comparison to joints from solder SnCu0.7.

  12. The Transport Equation in Optically Thick Media: Discussion of IMC and its Diffusion Limit

    Energy Technology Data Exchange (ETDEWEB)

    Szoke, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brooks, E. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-07-12

    We discuss the limits of validity of the Implicit Monte Carlo (IMC) method for the transport of thermally emitted radiation. The weakened coupling between the radiation and material energy of the IMC method causes defects in handling problems with strong transients. We introduce an approach to asymptotic analysis for the transport equation that emphasizes the fact that the radiation and material temperatures are always different in time-dependent problems, and we use it to show that IMC does not produce the correct diffusion limit. As this is a defect of IMC in the continuous equations, no improvement to its discretization can remedy it.

  13. Polarity effect of electromigration on kinetics of intermetallic compound formation in Pb-free solder V-groove samples

    Science.gov (United States)

    Gan, H.; Tu, K. N.

    2005-03-01

    Intermetallic compound (IMC) formation is critical for the reliability of microelectronic interconnections, especially for flip chip solder joints. In this article, we investigate the polarity effect of electromigration on kinetics of IMC formation at the anode and the cathode in solder V-groove samples. We use V-groove solder line samples, with width of 100 μm and length of 500-700 μm, to study interfacial IMC growth between Cu electrodes and Sn-3.8Ag-0.7Cu (in wt %) solder under different current density and temperature settings. The current densities are in the range of 103 to 104A/cm2 and the temperature settings are 120, 150, and 180 °C. While the same types of IMCs, Cu6Sn5 and Cu3Sn, form at the solder/Cu interfaces independent of the passage of electric current, the growth of the IMC layer has been enhanced by electric current at the anode and inhibited at the cathode, in comparison with the no-current case. We present a kinetic model, based on the Cu mass transport in the sample, to explain the growth rate of IMC at the anode and cathode. The growth of IMC at the anode follows a parabolic growth rule, and we propose that the back stress induced in the IMC plays a significant role. The model is in good agreement with our experimental data. We then discuss the influence of both chemical force and electrical force, and their combined effect on the IMC growth with electric current.

  14. Ramucirumab (IMC-1121B): a novel attack on angiogenesis.

    Science.gov (United States)

    Spratlin, Jennifer L; Mulder, Karen E; Mackey, John R

    2010-07-01

    Angiogenesis is a critical hallmark of malignancy, and attempts to inhibit this process have characterized the age of biologic anticancer therapies for solid tumors. VEGF receptor-2 is the premier receptor responsible for many of the cancer-driven VEGF-induced spectrum of biologic changes, including modification of blood vessel structure and function, proliferation and migration. Unlike all clinically approved angiogenesis inhibitors, the fully human monoclonal antibody ramucirumab (IMC-1121B) specifically and potently inhibits VEGF receptor-2. Phase I clinical trials have shown safety across a wide range of ramucirumab doses with impressive, albeit early, evidence of both stable disease and partial responses in a variety of tumor types. In this article, we review the current data on ramucirumab and make comparisons with commercially available antiangiogenic agents.

  15. Mechanical Characterization of Lead-Free Sn-Ag-Cu Solder Joints by High-Temperature Nanoindentation

    Science.gov (United States)

    Lotfian, S.; Molina-Aldareguia, J. M.; Yazzie, K. E.; Llorca, J.; Chawla, N.

    2013-06-01

    The reliability of Pb-free solder joints is controlled by their microstructural constituents. Therefore, knowledge of the solder microconstituents' mechanical properties as a function of temperature is required. Sn-Ag-Cu lead-free solder alloy contains three phases: a Sn-rich phase, and the intermetallic compounds (IMCs) Cu6Sn5 and Ag3Sn. Typically, the Sn-rich phase is surrounded by a eutectic mixture of β-Sn, Cu6Sn5, and Ag3Sn. In this paper, we report on the Young's modulus and hardness of the Cu6Sn5 and Cu3Sn IMCs, the β-Sn phase, and the eutectic compound, as measured by nanoindentation at elevated temperatures. For both the β-Sn phase and the eutectic compound, the hardness and Young's modulus exhibited strong temperature dependence. In the case of the intermetallics, this temperature dependence is observed for Cu6Sn5, but the mechanical properties of Cu3Sn are more stable up to 200°C.

  16. The iterative thermal emission method: A more implicit modification of IMC

    Energy Technology Data Exchange (ETDEWEB)

    Long, A.R., E-mail: arlong.ne@tamu.edu [Department of Nuclear Engineering, Texas A and M University, 3133 TAMU, College Station, TX 77843 (United States); Gentile, N.A. [Lawrence Livermore National Laboratory, L-38, P.O. Box 808, Livermore, CA 94550 (United States); Palmer, T.S. [Nuclear Engineering and Radiation Health Physics, Oregon State University, 100 Radiation Center, Corvallis, OR 97333 (United States)

    2014-11-15

    For over 40 years, the Implicit Monte Carlo (IMC) method has been used to solve challenging problems in thermal radiative transfer. These problems typically contain regions that are optically thick and diffusive, as a consequence of the high degree of “pseudo-scattering” introduced to model the absorption and reemission of photons from a tightly-coupled, radiating material. IMC has several well-known features that could be improved: a) it can be prohibitively computationally expensive, b) it introduces statistical noise into the material and radiation temperatures, which may be problematic in multiphysics simulations, and c) under certain conditions, solutions can be nonphysical, in that they violate a maximum principle, where IMC-calculated temperatures can be greater than the maximum temperature used to drive the problem. We have developed a variant of IMC called iterative thermal emission IMC, which is designed to have a reduced parameter space in which the maximum principle is violated. ITE IMC is a more implicit version of IMC in that it uses the information obtained from a series of IMC photon histories to improve the estimate for the end of time step material temperature during a time step. A better estimate of the end of time step material temperature allows for a more implicit estimate of other temperature-dependent quantities: opacity, heat capacity, Fleck factor (probability that a photon absorbed during a time step is not reemitted) and the Planckian emission source. We have verified the ITE IMC method against 0-D and 1-D analytic solutions and problems from the literature. These results are compared with traditional IMC. We perform an infinite medium stability analysis of ITE IMC and show that it is slightly more numerically stable than traditional IMC. We find that significantly larger time steps can be used with ITE IMC without violating the maximum principle, especially in problems with non-linear material properties. The ITE IMC method does

  17. Extension of IMC tuning correlations for non-self regulating (integrating) processes.

    Science.gov (United States)

    Arbogast, Jeffrey E; Cooper, Douglas J

    2007-06-01

    The filter term of a PID with Filter controller reduces the impact of measurement noise on the derivative action of the controller. This impact is quantified by the controller output travel defined as the total movement of the controller output per unit time. Decreasing controller output travel is important to reduce wear in the final control element. Internal Model Control (IMC) tuning correlations are widely published for PI, PID, and PID with Filter controllers for self regulating processes. For non-self regulating (or integrating) processes, IMC tuning correlations are published for PI and PID controllers but not for PID with Filter controllers. The important contribution of this work is that it completes the set of IMC tuning correlations with an extension to the PID with Filter controller for non-self regulating processes. Other published correlations (not based upon the IMC framework) for PID with Filter controllers fix the filter time constant at one-tenth the derivative time regardless of the model of the process. In contrast, the novel IMC correlations presented in this paper calculate a filter time constant based upon the model of the process and the user's choice for the closed-loop time constant. The set point tracking and disturbance rejection performance of the proposed IMC tunings is demonstrated using simulation studies and a bench-scale experimental system. The proposed IMC tunings are shown to perform as well as various PID correlations (with and without a filter term) while requiring considerably less controller action.

  18. Characterization of Low-Melting-Point Sn-Bi-In Lead-Free Solders

    Science.gov (United States)

    Li, Qin; Ma, Ninshu; Lei, YongPing; Lin, Jian; Fu, HanGuang; Gu, Jian

    2016-11-01

    Development of lead-free solders with low melting temperature is important for substitution of Pb-based solders to reduce direct risks to human health and the environment. In the present work, Sn-Bi-In solders were studied for different ratios of Bi and Sn to obtain solders with low melting temperature. The microstructure, thermal properties, wettability, mechanical properties, and reliability of joints with Cu have been investigated. The results show that the microstructures of the Sn-Bi-In solders were composed of β-Sn, Bi, and InBi phases. The intermetallic compound (IMC) layer was mainly composed of Cu6Sn5, and its thickness increased slightly as the Bi content was increased. The melting temperature of the solders was around 100°C to 104°C. However, when the Sn content exceeded 50 wt.%, the melting range became larger and the wettability became worse. The tensile strength of the solder alloys and solder joints declined with increasing Bi content. Two fracture modes (IMC layer fracture and solder/IMC mixed fracture) were found in solder joints. The fracture mechanism of solder joints was brittle fracture. In addition, cleavage steps on the fracture surface and coarse grains in the fracture structure were comparatively apparent for higher Bi content, resulting in decreased elongation for both solder alloys and solder joints.

  19. Identification and characterization of the inducible murine mast cell gene, imc-415.

    Science.gov (United States)

    Cho, S H; Cho, J J; Kim, I S; Vliagoftis, H; Metcalfe, D D; Oh, C K

    1998-11-01

    Activation of mast cells results in the generation and release of bioactive mediators which in turn initiate allergic inflammation. Mast cell function is enhanced following stimulation in part because of the induction of specific genes and their products. To identify additional genes induced in mast cells that support this process, we thus constructed an activation-specific mast cell subtraction library. To date, we have isolated 26 novel inducible murine mast cell (imc) cDNA clones. Among them, a full-coding region of the murine gene imc-415 was found to have a greater than 90% nucleotide sequence homology and a 97.5% amino acid sequence homology to both a human beta4 integrin-binding protein (p27(BBP)) and a human translation initiation factor 6 (eIF6), which in turn are identical. In vitro translation of the imc-415 gene yielded a band of an approximately 26 kDa. This is the same as the calculated molecular weight of murine IMC-415 protein based on the predicted amino acid sequence and is the molecular weight of p27(BBP)/eIF6. Murine imc-415 message was also induced in inflamed lung tissues in a mouse model of asthma. These results suggest a role for murine imc-415 in allergic inflammation where it may enhance protein synthesis. Human eIF6/p27(BBP) may also play a role in allergic diseases based on the similarities in sequence and in gene expression patterns.

  20. The alveolin IMC1h is required for normal ookinete and sporozoite motility behaviour and host colonisation in Plasmodium berghei.

    Directory of Open Access Journals (Sweden)

    Katrin Volkmann

    Full Text Available Alveolins, or inner membrane complex (IMC proteins, are components of the subpellicular network that forms a structural part of the pellicle of malaria parasites. In Plasmodium berghei, deletions of three alveolins, IMC1a, b, and h, each resulted in reduced mechanical strength and gliding velocity of ookinetes or sporozoites. Using time lapse imaging, we show here that deletion of IMC1h (PBANKA_143660 also has an impact on the directionality and motility behaviour of both ookinetes and sporozoites. Despite their marked motility defects, sporozoites lacking IMC1h were able to invade mosquito salivary glands, allowing us to investigate the role of IMC1h in colonisation of the mammalian host. We show that IMC1h is essential for sporozoites to progress through the dermis in vivo but does not play a significant role in hepatoma cell transmigration and invasion in vitro. Colocalisation of IMC1h with the residual IMC in liver stages was detected up to 30 hours after infection and parasites lacking IMC1h showed developmental defects in vitro and a delayed onset of blood stage infection in vivo. Together, these results suggest that IMC1h is involved in maintaining the cellular architecture which supports normal motility behaviour, access of the sporozoites to the blood stream, and further colonisation of the mammalian host.

  1. The alveolin IMC1h is required for normal ookinete and sporozoite motility behaviour and host colonisation in Plasmodium berghei.

    Science.gov (United States)

    Volkmann, Katrin; Pfander, Claudia; Burstroem, Charlotte; Ahras, Malika; Goulding, David; Rayner, Julian C; Frischknecht, Friedrich; Billker, Oliver; Brochet, Mathieu

    2012-01-01

    Alveolins, or inner membrane complex (IMC) proteins, are components of the subpellicular network that forms a structural part of the pellicle of malaria parasites. In Plasmodium berghei, deletions of three alveolins, IMC1a, b, and h, each resulted in reduced mechanical strength and gliding velocity of ookinetes or sporozoites. Using time lapse imaging, we show here that deletion of IMC1h (PBANKA_143660) also has an impact on the directionality and motility behaviour of both ookinetes and sporozoites. Despite their marked motility defects, sporozoites lacking IMC1h were able to invade mosquito salivary glands, allowing us to investigate the role of IMC1h in colonisation of the mammalian host. We show that IMC1h is essential for sporozoites to progress through the dermis in vivo but does not play a significant role in hepatoma cell transmigration and invasion in vitro. Colocalisation of IMC1h with the residual IMC in liver stages was detected up to 30 hours after infection and parasites lacking IMC1h showed developmental defects in vitro and a delayed onset of blood stage infection in vivo. Together, these results suggest that IMC1h is involved in maintaining the cellular architecture which supports normal motility behaviour, access of the sporozoites to the blood stream, and further colonisation of the mammalian host.

  2. Tuning of IMC based PID controllers for integrating systems with time delay.

    Science.gov (United States)

    Kumar, D B Santosh; Padma Sree, R

    2016-07-01

    Design of Proportional Integral and Derivative (PID) controllers based on IMC principles for various types of integrating systems with time delay is proposed. PID parameters are given in terms of process model parameters and a tuning parameter. The tuning parameter is IMC filter time constant. In the present work, the IMC filter (Q) is chosen in such a manner that the order of the denominator of IMC controller is one less than the order of the numerator. The IMC filter time constant (λ) is tuned in such a way that a good compromise is made between performance and robustness for both servo and regulatory problems. To improve servo response of the controller a set point filter is designed such that the closed loop response is similar to that of first order plus time delay system. The proposed controller design method is applied to various transfer function models and to the non-linear model equations of jacketed CSTR to demonstrate its applicability and effectiveness. The performance of the proposed controller is compared with the recently reported methods in terms of IAE and ITAE. The smooth functioning of the controller is determined in terms of total variation and compared with recently reported methods. Simulation studies are carried out on various integrating systems with time delay to show the effectiveness and superiority of the proposed controllers.

  3. Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8.

    Science.gov (United States)

    Li, Shiqing; Kussie, Paul; Ferguson, Kathryn M

    2008-02-01

    Therapeutic anticancer strategies that target and inactivate the epidermal growth factor receptor (EGFR) are under intense study in the clinic. Here we describe the mechanism of EGFR inhibition by an antibody drug IMC-11F8. IMC-11F8 is a fully human antibody that has similar antitumor potency as the chimeric cetuximab/Erbitux and might represent a safer therapeutic alternative. We report the X-ray crystal structure of the Fab fragment of IMC-11F8 (Fab11F8) in complex with the entire extracellular region and with isolated domain III of EGFR. We compare this to our previous study of the cetuximab/EGFR interaction. Fab11F8 interacts with a remarkably similar epitope, but through a completely different set of interactions. Both the similarities and differences in binding of these two antibodies have important implications for the development of inhibitors that could exploit this same mechanism of EGFR inhibition.

  4. IMC-PID design based on model matching approach and closed-loop shaping.

    Science.gov (United States)

    Jin, Qi B; Liu, Q

    2014-03-01

    Motivated by the limitations of the conventional internal model control (IMC), this communication addresses the design of IMC-based PID in terms of the robust performance of the control system. The IMC controller form is obtained by solving an H-infinity problem based on the model matching approach, and the parameters are determined by closed-loop shaping. The shaping of the closed-loop transfer function is considered both for the set-point tracking and for the load disturbance rejection. The design procedure is formulated as a multi-objective optimization problem which is solved by a specific optimization algorithm. A nice feature of this design method is that it permits a clear tradeoff between robustness and performance. Simulation examples show that the proposed method is effective and has a wide applicability.

  5. Performance assessment of PID and IMC tuning methods for a mixing process with time delay.

    Science.gov (United States)

    Selvi, J Arputha Vijaya; Radhakrishnan, T K; Sundaram, S

    2007-06-01

    A flow process with time delay has been considered for modeling and control. A dilute solution of sodium chloride is used as tracer and an online conductivity measurement unit as sensor and recorder. The objective of the current study is to design control algorithms and present corresponding robust control analysis for the process. The control methodologies considered are (i) conventional PID control and (ii) internal model control (IMC). The control structures are comparatively analyzed using standard robustness measures for stability and performance. Of the two control algorithms, conventional PID and IMC, IMC exhibits faster settling time, no overshoot, better set-point tracking and disturbance rejection, and good robust performance than the PID control scheme.

  6. PI/PID controller design based on IMC and percentage overshoot specification to controller setpoint change.

    Science.gov (United States)

    Ali, Ahmad; Majhi, Somanath

    2009-01-01

    In this work, the normalized Internal Model Control (IMC) filter time constant is designed to achieve a specified value of the maximum sensitivity for stable first and second order plus time delay process models, respectively. Since a particular value of the maximum sensitivity results in an almost constant percentage overshoot to controller setpoint change, an empirical relationship between the normalized IMC filter time constant and percentage overshoot is presented. The main advantage of the proposed method is that only a user-defined overshoot is required to design a PI/PID controller. Simulation examples are given to demonstrate the value of the proposed method.

  7. Analysis of Robustness of PID-GPC Based on IMC Structure

    Institute of Scientific and Technical Information of China (English)

    陈增强; 毛宗星; 等

    2003-01-01

    Proportion integral differential generalized predictive control(PID-GPC),a new type of generalized predictive control(GPC) is introduced,and its quality is analyzed with internal model contron(IMC).A very important characteristic,which distinguishes GPC from ordinary IMC,and the robust effect are found.At the same time,a robust region is obtained according to the control laws,so that the defect that the robust analysis could be carried out only with stable models is vercome.It is verified that the robustness of PID-GPC is stronger than general GPC.

  8. New tuning rules for PID controllers based on IMC with minimum IAE for inverse response processes

    Directory of Open Access Journals (Sweden)

    Duby Castellanos-Cárdenas

    2015-01-01

    Full Text Available In this paper new tuning rules for Proportional Integral Derivative (PID are presented, which are based on Internal Model Control (IMC. This set of equations minimizes the performance index, in this case, the Integral Absolute Error (IAE. Furthermore, a correlation is proposed in order to calculate the tuning parameter of the method, where a holding oscillation response is obtained regarding changes in the set point. This value represents a stability limit for the IMC method. The overall development is then applied to an Inverse Response System of second order and with dead time.

  9. Electromigration Behaviors of Cu Reinforced Sn-3.5Ag Composite Solder Joints

    Science.gov (United States)

    Wang, Yan; Han, Jing; Ma, Limin; Zuo, Yong; Guo, Fu

    2016-09-01

    The composite approach, by incorporating small amounts of reinforcement particles in the solder matrix, has proven to be one of the effective ways to improve the reliability of solder joints. The effects of Cu addition on electromigration were investigated in this study by incorporating 2% volume fraction Cu particles into Sn-3.5Ag eutectic solder paste by the in situ process. The one-dimensional solder joints, designed to prevent the current crowding effect, were stressed under a constant current density of 104 A/cm2 at room temperature, and the temperature of the sample could reach 105 ± 5°C due to the Joule heating effect. Doping 2 vol.% Cu was found to retard the electromigration phenomenon effectively. After electric current stressing for 528 h, the growth rate of an interfacial intermetallic compound (IMC) layer at the anode decreased 73% in contrast to that of Sn-3.5Ag solder joints, and the IMC layer at the cathode was almost unchanged. The polarization effect of Cu reinforced composite solder joints was also apparently mitigated. In addition, the surface damage of the composite solder joints was relieved by incorporating 2 vol.% Cu particles. Compared to Sn-3.5Ag solder joints, which had protruded Cu6Sn5 and wrinkles of Sn-solder matrix on the surface, the solder joints with Cu addition had a more even surface.

  10. Electromigration Behaviors of Cu Reinforced Sn-3.5Ag Composite Solder Joints

    Science.gov (United States)

    Wang, Yan; Han, Jing; Ma, Limin; Zuo, Yong; Guo, Fu

    2016-12-01

    The composite approach, by incorporating small amounts of reinforcement particles in the solder matrix, has proven to be one of the effective ways to improve the reliability of solder joints. The effects of Cu addition on electromigration were investigated in this study by incorporating 2% volume fraction Cu particles into Sn-3.5Ag eutectic solder paste by the in situ process. The one-dimensional solder joints, designed to prevent the current crowding effect, were stressed under a constant current density of 104 A/cm2 at room temperature, and the temperature of the sample could reach 105 ± 5°C due to the Joule heating effect. Doping 2 vol.% Cu was found to retard the electromigration phenomenon effectively. After electric current stressing for 528 h, the growth rate of an interfacial intermetallic compound (IMC) layer at the anode decreased 73% in contrast to that of Sn-3.5Ag solder joints, and the IMC layer at the cathode was almost unchanged. The polarization effect of Cu reinforced composite solder joints was also apparently mitigated. In addition, the surface damage of the composite solder joints was relieved by incorporating 2 vol.% Cu particles. Compared to Sn-3.5Ag solder joints, which had protruded Cu6Sn5 and wrinkles of Sn-solder matrix on the surface, the solder joints with Cu addition had a more even surface.

  11. Astronomy through the microscope: A workshop during the opening night of the 2016 IMC

    Science.gov (United States)

    Netjes, G. J.; de Vet, S.

    2016-01-01

    During the IMC workshop meteoritical thins sections were shown live with a microscope connected to the beamer. This article will provide a background to thin sections, what we can learn from them and the tour through the solar system we can take with them.

  12. Understanding the development and diffusion of integrated marketing communications (IMC) : A metaphorical perspective

    NARCIS (Netherlands)

    Cornelissen, J.P.; Thøger, L.; Vijn, P.

    2006-01-01

    In recent years, theoretical commentaries and empirical research on the concept of Integrated Marketing Communications (IMC) have been concerned with its development and specification as a theoretical construct, and its diffusion among academics and practitioner populations across the globe. In this

  13. An Analysis of Source Tilting and Sub-cell Opacity Sampling for IMC

    Energy Technology Data Exchange (ETDEWEB)

    Wollaeger, Ryan T. [Los Alamos National Laboratory; Urbatsch, Todd J. [Los Alamos National Laboratory; Wollaber, Allan B. [Los Alamos National Laboratory; Densmore, Jeffery D. [Los Alamos National Laboratory

    2012-08-02

    Implicit Monte Carlo (IMC) is a stochastic method for solving the radiative transfer equations for multiphysics application with the material in local thermodynamic equilibrium. The IMC method employs a fictitious scattering term that is computed from an implicit discretization of the material temperature equation. Unfortunately, the original histogram representation of the temperature and opacity with respect to the spatial domain leads to nonphysically fast propagation of radiation waves through optically thick material. In the past, heuristic source tilting schemes have been used to mitigate the numerical teleportation error of the radiation particles in IMC that cause this overly rapid radiation wave propagation. While improving the material temperature profile throughout the time duration, these tilting schemes alone do not generally alleviate the teleportation error to suitable levels. Another means of potentially reducing teleportation error in IMC is implementing continuous sub-cell opacities based on sub-cell temperature profiles. We present here an analysis of source tilting and continuous sub-cell opacity sampling applied to various discretizations of the temperature equation. Through this analysis, we demonstrate that applying both heuristics does not necessarily yield more accurate results if the discretization of the material equation is inconsistent with the Monte Carlo sub-cell transport.

  14. Antitumor Activity of IMC-038525, a Novel Oral Tubulin Polymerization Inhibitor.

    Science.gov (United States)

    Tuma, Maria Carolina; Malikzay, Asra; Ouyang, Xiaohu; Surguladze, David; Fleming, James; Mitelman, Stan; Camara, Margarita; Finnerty, Bridget; Doody, Jacqueline; Chekler, Eugene L P; Kussie, Paul; Tonra, James R

    2010-10-01

    Microtubules are a well-validated target for anticancer therapy. Molecules that bind tubulin affect dynamic instability of microtubules causing mitotic arrest of proliferating cells, leading to cell death and tumor growth inhibition. Natural antitubulin agents such as taxanes and Vinca alkaloids have been successful in the treatment of cancer; however, several limitations have encouraged the development of synthetic small molecule inhibitors of tubulin function. We have previously reported the discovery of two novel chemical series of tubulin polymerization inhibitors, triazoles (Ouyang et al. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors. Bioorg Med Chem Lett. 2005; 15:5154-5159) and oxadiazole derivatives (Ouyang et al. Oxadiazole derivatives as a novel class of antimitotic agents: synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines. Bioorg Med Chem Lett. 2006; 16:1191-1196). Here, we report on the anticancer effects of a lead oxadiazole derivative in vitro and in vivo. In vitro, IMC-038525 caused mitotic arrest at nanomolar concentrations in epidermoid carcinoma and breast tumor cells, including multidrug-resistant cells. In vivo, IMC-038525 had a desirable pharmacokinetic profile with sustained plasma levels after oral dosing. IMC-038525 reduced subcutaneous xenograft tumor growth with significantly greater efficacy than the taxane paclitaxel. At efficacious doses, IMC-038525 did not cause substantial myelosuppression or peripheral neurotoxicity, as evaluated by neutrophil counts and changes in myelination of the sciatic nerve, respectively. These data indicate that IMC-038525 is a promising candidate for further development as a chemotherapeutic agent.

  15. In vitro evaluation of antimicrobial activity of Lactobacillus rhamnosus IMC 501(®) , Lactobacillus paracasei IMC 502(®) and SYNBIO(®) against pathogens.

    Science.gov (United States)

    Coman, M M; Verdenelli, M C; Cecchini, C; Silvi, S; Orpianesi, C; Boyko, N; Cresci, A

    2014-08-01

    Probiotic lactobacilli have a great potential to produce antimicrobial compounds that inhibit and control the microbial pathogen growth. The antimicrobial and antifungal activities of two probiotic strains, Lactobacillus rhamnosus IMC 501(®) and Lactobacillus paracasei IMC 502(®) , and their 1 : 1 combination, named SYNBIO(®) , were studied using four different methods. Using two modified streak methods and a well diffusion method, the inhibitory activity of the probiotics and their metabolites towards six Gram-positive, nine Gram-negative pathogenic bacterial strains and eight Candida strains was tested. Antagonistic effect of probiotic Lactobacillus strains was also investigated by coculturing assay highlighting a significant inhibition of most of the pathogens tested in this study. The combination SYNBIO(®) showed a microbicidal activity against most of the strains tested in the study. Compared with the control, most of the pathogenic bacteria and yeast were inhibited by all probiotic strains tested to various degrees. Screening Lactobacillus strains according to their activity in various environmental conditions could precede the clinical efficacy studies for adjunct treatment with probiotics in cure of different gastrointestinal and vaginal tract infections. © 2014 The Society for Applied Microbiology.

  16. Effect of Cu concentration on morphology of Sn-Ag-Cu solders by mechanical alloying

    Science.gov (United States)

    Kao, Szu-Tsung; Duh, Jenq-Gong

    2004-12-01

    The mechanical alloying (MA) process is considered an alternative approach to produce solder materials. In this study, the effect of Cu concentration in the ternary Sn-3.5Ag-xCu (x=0.2, 0.7, and 1) solder by MA was investigated. The (Cu,Sn) solid solution was precipitated as the Cu6Sn5 intermetallic compound (IMC), which was distributed nonuniformly through the microstructure. The Cu6Sn5 IMC, which was present in the SnAgCu solder with high Cu composition, causes the as-milled MA particle to fracture to a smaller size. Appreciable distinction on morphology of as-milled MA powders with different Cu content was revealed. When the Cu concentration was low (x=0.2), MA particle aggregated to a spherical ingot with large particle size. For higher Cu concentration (x=0.7 and x=1), the MA particle turned to flakes with smaller particle size. The distinction of the milling mechanism of Sn-3.5Ag-xCu (x=0.2, 0.7, and 1) solder by the MA process was discussed. An effective approach was developed to reduce the particle size of the SnAgCu solder from 1 mm down to 10-100 µm by doping the Cu6Sn5 nanoparticle during the MA process. In addition, the differential scanning calorimetry (DSC) results also ensure the compatibility to apply the solder material for the reflow process.

  17. IMC based feedforward controller framework for disturbance attenuation on uncertain systems.

    Science.gov (United States)

    Vilanova, R; Arrieta, O; Ponsa, P

    2009-10-01

    This paper presents a generalization of the Internal Model Control (IMC) approach to feedforward control action generation. As is well known, one of the distinctive features of the IMC formulation is the possibility to distinguish between the nominal and uncertain situations. However the consideration of the presence of uncertainty for the feedforward part of the controller is not as simple as that for the feedback one. In this sense, what is proposed in this paper provides a more systematic way of addressing a robust feedforward design. In addition, being one of the major drawbacks of the Internal Model Control to have to deal with stable systems, the generalization presented here allows for unstable plants as well as unstable disturbance models.

  18. Substrate-induced activation of a trapped IMC-mediated protein folding intermediate.

    Science.gov (United States)

    Inouye, M; Fu, X; Shinde, U

    2001-04-01

    While several unfolded proteins acquire native structures through distinct folding intermediates, the physiological relevance and importance of such states in the folding kinetics remain controversial. The intramolecular chaperone (IMC) of subtilisin was used to trap a partially folded, stable crosslinked intermediate conformer (CLIC) through a disulfide bond between mutated IMC and subtilisin. The trapped CLIC contains non-native interactions. Here we show that CLIC can be induced into a catalytically active form by incubating it with small peptide substrates. The structure and catalytic properties of the activated crosslinked intermediate conformer (A-CLIC) differ from those of the fully folded enzyme in that A-CLIC lacks any endopeptidase activity toward a large protein substrate. Our results show that a disulfide-linked partially folded protein can be induced to acquire catalytic activity with a substrate specificity that is different from completely folded subtilisin. These results also suggest that protein folding intermediates may also participate in catalytic reactions.

  19. Safety experience with IMC-C225, an anti-epidermal growth factor receptor antibody.

    Science.gov (United States)

    Needle, Michael N

    2002-10-01

    In phase II trials, the anti-epidermal growth factor receptor antibody IMC-C225 did not appear to significantly exacerbate the common toxicities associated with cytotoxic chemotherapy when combined with standard anticancer treatments in patients with colorectal cancer, squamous cell carcinoma of the head and neck, or pancreatic cancer. The most common treatment-related adverse events reported during therapy with IMC-C225 were an acne-like rash and hypersensitivity reactions. The acne-like rash appeared as a sterile, suppurative form of folliculitis, commonly starting on the face, scalp, chest, and upper back. It resolved without scarring once treatment was stopped. Notably, the appearance of acne-like rash, particularly grade 3, was associated with higher treatment responses in patients with refractory colorectal cancer. The hypersensitivity reactions occurred less often than acne-like rash. They responded to standard treatments and were less common after the first dose. In summary, IMC-C225 is generally well tolerated as a single agent and when combined with chemotherapy or radiotherapy and possesses a manageable toxicity profile.

  20. Characteristics of indomethacin-saccharin (IMC-SAC) co-crystals prepared by an anti-solvent crystallization process.

    Science.gov (United States)

    Chun, Nan-Hee; Wang, In-Chun; Lee, Min-Jeong; Jung, Yun-Taek; Lee, Sangkil; Kim, Woo-Sik; Choi, Guang J

    2013-11-01

    The creation of co-crystals of various insoluble drug substances has been extensively investigated as a promising approach to improve their pharmaceutical performance. In this study, co-crystal powders of indomethacin and saccharin (IMC-SAC) were prepared by an anti-solvent (water) addition and compared with co-crystals by evaporation method. No successful synthesis of a pharmaceutical co-crystal powder via an anti-solvent approach has been reported. Among solvents examined, methanol was practically the only one that resulted in the formation of highly pure IMC-SAC co-crystal powders by anti-solvent approach. The mechanism of a preferential formation of IMC-SAC co-crystal to IMC was explained with two aspects: phase solubility diagram and solution complexation concept. Accordingly, the anti-solvent approach can be considered as a competitive route for producing pharmaceutical co-crystal powders with acceptable properties.

  1. Spreading Behavior and Evolution of IMCs During Reactive Wetting of SAC Solders on Smooth and Rough Copper Substrates

    Science.gov (United States)

    Satyanarayan; Prabhu, K. N.

    2013-08-01

    The effect of surface roughness of copper substrate on the reactive wetting of Sn-Ag-Cu solder alloys and morphology of intermetallic compounds (IMCs) was investigated. The spreading behavior of solder alloys on smooth and rough Cu substrates was categorized into capillary, diffusion/reaction, and contact angle stabilization zones. The increase in substrate surface roughness improved the wetting of solder alloys, being attributed to the presence of thick Cu3Sn IMC at the interface. The morphology of IMCs transformed from long needle shaped to short protruded type with an increase in the substrate surface roughness for the Sn-0.3Ag-0.7Cu and Sn-3Ag-0.5Cu solder alloys. However, for the Sn-2.5Ag-0.5Cu solder alloy the needle-shaped IMCs transformed to the completely scallop type with increase in the substrate surface roughness. The effect of Ag content on wetting behavior was not significant.

  2. Toxoplasma ISP4 is a central IMC sub-compartment protein whose localization depends on palmitoylation but not myristoylation.

    Science.gov (United States)

    Fung, Connie; Beck, Josh R; Robertson, Seth D; Gubbels, Marc-Jan; Bradley, Peter J

    2012-08-01

    Apicomplexan parasites utilize a peripheral membrane system called the inner membrane complex (IMC) to facilitate host cell invasion and parasite replication. We recently identified a novel family of Toxoplasma IMC Sub-compartment Proteins (ISP1/2/3) that localize to sub-domains of the IMC using a targeting mechanism that is dependent on coordinated myristoylation and palmitoylation of a series of residues in the N-terminus of the protein. While the precise functions of the ISPs are unknown, deletion of ISP2 results in replication defects, suggesting that this family of proteins plays a role in daughter cell formation. Here we have characterized a fourth ISP family member (ISP4) and discovered that this protein localizes to the central IMC sub-compartment, similar to ISP2. Like ISP1/3, ISP4 is dispensable for the tachyzoite lytic cycle as the disruption of ISP4 does not produce any gross replication or growth defects. Surprisingly, targeting of ISP4 to the IMC membranes is dependent on residues predicted for palmitoylation but not myristoylation, setting its trafficking apart from the other ISP proteins and demonstrating distinct mechanisms of protein localization to the IMC membranes, even within a family of highly related proteins.

  3. A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division.

    Science.gov (United States)

    Beck, Josh R; Rodriguez-Fernandez, Imilce A; de Leon, Jessica Cruz; Huynh, My-Hang; Carruthers, Vern B; Morrissette, Naomi S; Bradley, Peter J

    2010-09-09

    Apicomplexans employ a peripheral membrane system called the inner membrane complex (IMC) for critical processes such as host cell invasion and daughter cell formation. We have identified a family of proteins that define novel sub-compartments of the Toxoplasma gondii IMC. These IMC Sub-compartment Proteins, ISP1, 2 and 3, are conserved throughout the Apicomplexa, but do not appear to be present outside the phylum. ISP1 localizes to the apical cap portion of the IMC, while ISP2 localizes to a central IMC region and ISP3 localizes to a central plus basal region of the complex. Targeting of all three ISPs is dependent upon N-terminal residues predicted for coordinated myristoylation and palmitoylation. Surprisingly, we show that disruption of ISP1 results in a dramatic relocalization of ISP2 and ISP3 to the apical cap. Although the N-terminal region of ISP1 is necessary and sufficient for apical cap targeting, exclusion of other family members requires the remaining C-terminal region of the protein. This gate-keeping function of ISP1 reveals an unprecedented mechanism of interactive and hierarchical targeting of proteins to establish these unique sub-compartments in the Toxoplasma IMC. Finally, we show that loss of ISP2 results in severe defects in daughter cell formation during endodyogeny, indicating a role for the ISP proteins in coordinating this unique process of Toxoplasma replication.

  4. A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division.

    Directory of Open Access Journals (Sweden)

    Josh R Beck

    Full Text Available Apicomplexans employ a peripheral membrane system called the inner membrane complex (IMC for critical processes such as host cell invasion and daughter cell formation. We have identified a family of proteins that define novel sub-compartments of the Toxoplasma gondii IMC. These IMC Sub-compartment Proteins, ISP1, 2 and 3, are conserved throughout the Apicomplexa, but do not appear to be present outside the phylum. ISP1 localizes to the apical cap portion of the IMC, while ISP2 localizes to a central IMC region and ISP3 localizes to a central plus basal region of the complex. Targeting of all three ISPs is dependent upon N-terminal residues predicted for coordinated myristoylation and palmitoylation. Surprisingly, we show that disruption of ISP1 results in a dramatic relocalization of ISP2 and ISP3 to the apical cap. Although the N-terminal region of ISP1 is necessary and sufficient for apical cap targeting, exclusion of other family members requires the remaining C-terminal region of the protein. This gate-keeping function of ISP1 reveals an unprecedented mechanism of interactive and hierarchical targeting of proteins to establish these unique sub-compartments in the Toxoplasma IMC. Finally, we show that loss of ISP2 results in severe defects in daughter cell formation during endodyogeny, indicating a role for the ISP proteins in coordinating this unique process of Toxoplasma replication.

  5. Sensitivity analysis of helicopter IMC decelerating steep approach and landing performance to navigation system parameters

    Science.gov (United States)

    Karmali, M. S.; Phatak, A. V.

    1982-01-01

    Results of a study to investigate, by means of a computer simulation, the performance sensitivity of helicopter IMC DSAL operations as a function of navigation system parameters are presented. A mathematical model representing generically a navigation system is formulated. The scenario simulated consists of a straight in helicopter approach to landing along a 6 deg glideslope. The deceleration magnitude chosen is 03g. The navigation model parameters are varied and the statistics of the total system errors (TSE) computed. These statistics are used to determine the critical navigation system parameters that affect the performance of the closed-loop navigation, guidance and control system of a UH-1H helicopter.

  6. An application of the IMC software to controller design for the JPL LSCL Experiment Facility

    Science.gov (United States)

    Zhu, Guoming; Skelton, Robert E.

    1993-01-01

    A software package which Integrates Model reduction and Controller design (The IMC software) is applied to design controllers for the JPL Large Spacecraft Control Laboratory Experiment Facility. Modal Cost Analysis is used for the model reduction, and various Output Covariance Constraints are guaranteed by the controller design. The main motivation is to find the controller with the 'best' performance with respect to output variances. Indeed it is shown that by iterating on the reduced order design model, the controller designed does have better performance than that obtained with the first model reduction.

  7. Avian Imc-tectal projection is mediated by acetylcholine and glutamate.

    Science.gov (United States)

    Wang, S R; Wu, G Y; Felix, D

    1995-03-27

    In the bird, biochemical and histochemical data suggest that the neurotransmitter between nucleus isthmi pars magnocellularis (Imc) and tectum is either acetylcholine or glutamate. There are, however, discrepancies regarding the functional role of acetylcholine. In the present study we investigated the action of acetylcholine and glutamate and their specific antagonists on excitatory isthmo-tectal synaptic transmission using electrophysiological and microiontophoretic techniques. The results show two different population of cells: (1) excitatory cholinergic input, blocked by atropine sulphate but not by glutamate antagonist; (2) excitatory glutamatergic input of NMDA or non-NMDA receptor type, which is blocked or reduced by CPP or CNQX but not by atropine sulphate.

  8. Coordinating IMC-PID and adaptive SMC controllers for a PEMFC.

    Science.gov (United States)

    Wang, Guo-Liang; Wang, Yong; Shi, Jun-Hai; Shao, Hui-He

    2010-01-01

    For a Proton Exchange Membrane Fuel Cell (PEMFC) power plant with a methanol reformer, the process parameters and power output are considered simultaneously to avoid violation of the constraints and to keep the fuel cell power plant safe and effective. In this paper, a novel coordinating scheme is proposed by combining an Internal Model Control (IMC) based PID Control and adaptive Sliding Mode Control (SMC). The IMC-PID controller is designed for the reformer of the fuel flow rate according to the expected first-order dynamic properties. The adaptive SMC controller of the fuel cell current has been designed using the constant plus proportional rate reaching law. The parameters of the SMC controller are adaptively tuned according to the response of the fuel flow rate control system. When the power output controller feeds back the current references to these two controllers, the coordinating controllers system works in a system-wide way. The simulation results of the PEMFC power plant demonstrate the effectiveness of the proposed method.

  9. Enhanced IMC design of load disturbance rejection for integrating and unstable processes with slow dynamics.

    Science.gov (United States)

    Liu, Tao; Gao, Furong

    2011-04-01

    In view of the deficiencies in existing internal model control (IMC)-based methods for load disturbance rejection for integrating and unstable processes with slow dynamics, a modified IMC-based controller design is proposed to deal with step- or ramp-type load disturbance that is often encountered in engineering practices. By classifying the ways through which such load disturbance enters into the process, analytical controller formulae are correspondingly developed, based on a two-degree-of-freedom (2DOF) control structure that allows for separate optimization of load disturbance rejection from setpoint tracking. An obvious merit is that there is only a single adjustable parameter in the proposed controller, which in essence corresponds to the time constant of the closed-loop transfer function for load disturbance rejection, and can be monotonically tuned to meet a good trade-off between disturbance rejection performance and closed-loop robust stability. At the same time, robust tuning constraints are given to accommodate process uncertainties in practice. Illustrative examples from the recent literature are used to show effectiveness and merits of the proposed method for different cases of load disturbance.

  10. Influence of IMC in the Semisolid Behaviour of an Eutectic Sn-Pb/Cu Slurry

    Science.gov (United States)

    Merizalde, Carlos; Cabrera, José-María; Prado, José-Manuel

    2007-04-01

    A mixture of a liquid Sn-Pb alloy reinforced with solid Cu particles has been found to show thixotropic and pseudoplastic behaviour. The presence of an intermetallic compound (IMC) between the Cu particles and the molten matrix has some very important consequences in the rheological behaviour of the slurry. The semisolid material is obtained mixing a sufficient amount of Cu particles with a liquid eutectic Sn-Pb alloy by mechanical stirring at a given temperature and time. The intermetallic compound is formed from the reaction of solid Cu and liquid Sn. This reaction results in some displacement in the phase diagram, affecting the liquid alloy composition, moving the liquidus temperature and therefore altering the balance of %wt solid- %wt liquid necessary to obtain the best thixotropic behaviour. In this work a model of the solid fraction of the slurry taking into account the IMC growth rate is presented. This model is also used to predict the processing window under which the material keeps the thixotropic behaviour.

  11. Hypertrophy of IMC of carotid artery in Parkinson's disease is associated with L-DOPA, homocysteine, and MTHFR genotype.

    Science.gov (United States)

    Nakaso, Kazuhiro; Yasui, Kenichi; Kowa, Hisanori; Kusumi, Masayoshi; Ueda, Keigo; Yoshimoto, Yuko; Takeshima, Takao; Sasaki, Kiyohiro; Nakashima, Kenji

    2003-03-15

    In recent years, an intense interest has developed in the association between Parkinson's disease (PD) and hyperhomocysteinemia. Homocysteine (Hcy) is a neuronal excitotoxic amino acid, and is well known as a risk factor for vascular diseases. Some reports suggest that the administration of L-DOPA may promote hyperhomocysteinemia and idiopathic atherosclerosis. In this study, we report that a mild hypertrophy of the intima-media complex (IMC) of the carotid artery, which has been established as a marker for systemic atherosclerosis, is observed in PD patients compared with normal subjects. PD patients that were treated with L-DOPA for long durations showed a hypertrophic IMC, while the patients that were not treated with L-DOPA did not show any hypertrophic changes in the IMC. These hypertrophic changes were observed primarily in patients with a Hoehn-Yahr stage of 3-5. PD patients with hypertrophic IMC of the carotid artery also exhibited elevated plasma levels of Hcy associated with the C677T genotype of 5,10-methylenetetrahydrofolate reductase (MTHFR). Moreover, a prolonged duration of treatment with L-DOPA in patients with MTHFR T/T genotype enhanced the hypertrophy of IMC, compared with patients with the C/C or C/T genotype. These results suggest that hyperhomocysteinemia promoted by the C677T genotype of MTHFR and prolonged treatment with L-DOPA enhances atherosclerosis in PD patients and affects their general condition.

  12. 整合营销传播(IMC)理论精要及其发展方向(上)%the Soul and Direction of IMC

    Institute of Scientific and Technical Information of China (English)

    杨明刚

    2004-01-01

    20世纪90年代以来,作为一种新的营销传播方式,整合营销传播(Integrated Marketing Communication,简称IMC)风靡西方广告界、媒体界、企业界,并获得了快速的发展和应用。IMC已成为一种新趋势、新理念、新理论和新方法。目前,尽管IMC还处于正在不断完善与实践阶段,但它的兴起与进一步发展已打破了营销领域中占重要地位的结构性概念,即4P(Product、Price、Place、Promotion)为核心的营销框架,并显示出将替代传统营销理论而成为主流范式的征兆。

  13. 基于VRFT的IMC-PID方法及其在水厂浊度控制中的仿真研究%Research on VRFT-based IMC-PID Method and Simulation of Turbidity Control in Water Supply Plant

    Institute of Scientific and Technical Information of China (English)

    哀微; 朱学峰

    2011-01-01

    Considering the nonlinearity and time-variant, large time constant and dead time in water supply proeess,a data-driven method virtual reference feedback tuning(VRFT) was introduced to the IMC-PID tuning, and a novel VRFT-IMC tuning method without using model parameters was presented. This method combines strong robust in IMC and model-free adaptive in data-driven control. Simulation results show that IMCPID method based on VRFT outperforms the traditional IMC-PID, and can be used for initial tuning of the controller and auto-tuning in the turbidity control.%针对城市供水出水浊度过程的大惯性、大时滞、非线性以及时变等特点,将虚拟参考反馈整定数据驱动方法引入到IMC-PID控制器的整定中来,提出了一种不基于模型参数的VRFT-IMC参数整定方法.该方法集合了内模控制鲁棒性强和数据驱动控制的自适应性两方面的优点,仿真表明其控制性能优于普通IMC-PID控制器,可望用于出水浊度等复杂过程控制器参数的初始整定和实时自整定.

  14. Correlations between IMC thickness and three factors in Sn-3Ag-0.5Cu alloy system

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The effects of Ni content, soldering temperature and time on the IMC thickness in Sn-3Ag-0.5Cu and Sn-3Ag-0.5Cu-0.2Co alloys were researched using uniform design method and computer programs. For each alloy, the factors were divided into three levels in the experiment. Two correlative equations are given by regression. They indicate that the effects of three factors on the function are in the mutual and quadratic forms. And the analysis of variance shows the equations are sound and meaningful. Using the equations, it is easy to search, predict and control the IMC thickness. The existence of element Co accelerates the crystallization and growing up of IMC.

  15. IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer.

    Science.gov (United States)

    Herbst, Roy S; Hong, Waun Ki

    2002-10-01

    Squamous cell carcinoma of the head and neck remains a clinical challenge because of the high rate of locoregional disease recurrence. The importance of the epidermal growth factor receptor (EGFR) in the development and progression of many solid tumors, including squamous cell carcinoma of the head and neck, is well understood; increased expression is associated with enhanced tumor invasiveness, resistance to chemotherapy, and a lower patient survival rate. Several approaches have been developed to achieve EGFR blockade as an anticancer treatment strategy, including the anti-EGFR monoclonal antibody IMC-C225, which competitively binds to the extracellular receptor site and prevents binding by the natural EGFR ligands EGF and transforming growth factor-alpha. Preclinical studies to evaluate IMC-225 in human cancer cell lines in vitro and human tumor xenografts in vivo have shown its potent antitumor activity. Clinical efficacy of IMC-C225 appears to involve multiple mechanisms, including inhibition of cell cycle progression, induction of apoptosis, inhibition of angiogenesis, inhibition of metastasis, and enhancement of the response to chemotherapy and radiation therapy. Phase I studies of IMC-C225 combined with chemotherapy or radiation showed promising response rates in patients with recurrent or refractory squamous cell carcinoma of the head and neck. Phase II and III trials to examine the efficacy and safety of these combinations are currently underway. To date, IMC-C225 has been well tolerated, with skin rashes and allergic reactions being the most clinically important adverse events reported. IMC-C225 displays dose-dependent elimination characteristics and a half-life of approximately 7 days. Current recommendations for dosing include a 400 mg/m(2) loading dose, followed by weekly infusions at 250 mg/m(2).

  16. A Practical Application of IMC-PID Controller in Unmanned Vehicle

    Directory of Open Access Journals (Sweden)

    Qin Gang

    2013-06-01

    Full Text Available In allusion to unmanned vehicle steering control of the brushless DC motor control system, traditional PID controller parameter adjustment complex, weak ability to adapt to the environment and other issues, on the basis of the analysis of internal model control and classical PID control internal corresponding relationship, comprehensive its advantages, The design uses a brushless DC motor in the steering control system for unmanned vehicles based on the internal model PID controller ( IMC-PID for speed. Based on the build object theoretical model, online simulation controller show that, for the design objects, based on the internal model PID controller whether the system step response or disturbance tracking control effect can reach the classic PID control requirements, also reduces the complexity and randomness of the design parameters.

  17. Design of Dynamic Quantizers in Two Degree of Freedom IMC for Input-delay Plant

    Science.gov (United States)

    Okajima, Hiroshi; Umemoto, Tatsuya; Matsunaga, Nobutomo; Kawaji, Shigeyasu

    It is well known that plants with time delay are hard to be controlled by using traditional method. For this, controller with delay, such as Internal Model Control (IMC), Smith-method, have been proposed for input-delay systems. However, it would be difficult to realize the delay of controller because of memory limit of micro control unit(MCU). Also, the sampling time might be large in case of the application to the plant with large time delay, because of the limitation of the memory in MCU. Hence, the trade-off exists between sampling time and maximum quantizing error, and the assignment of the quantizer affects the quantization error. In this paper, dynamic quantizers are designed for achieving small quantizing error for input-delay control systems in MCU system. Also, the attainable performance caused by assignment of the quantizer is discussed. The effectiveness of the proposed method is shown by numerical example.

  18. Ramucirumab (IMC-1121B): Monoclonal antibody inhibition of vascular endothelial growth factor receptor-2.

    Science.gov (United States)

    Spratlin, Jennifer

    2011-04-01

    Angiogenesis, a well-recognized characteristic of malignancy, has been exploited more than any other pathway targeted by biologic anti-neoplastic therapies. Vascular endothelial growth factor receptor-2 (VEGFR-2) is the critical receptor involved in malignant angiogenesis with its activation inducing a number of other cellular modifications resulting in tumor growth and metastases. Ramucirumab (IMC-1121B; ImClone Systems Corporation, Branchburg, NJ) is a fully human monoclonal antibody developed to specifically inhibit VEGFR-2. Ramucirumab is currently being investigated in multiple clinical trials across a variety of tumor types. Herein, angiogenesis inhibition in cancer is reviewed and up-to-date information on the clinical development of ramucirumab is presented.

  19. Effectively Transforming IMC Flight into VMC Flight: An SVS Case Study

    Science.gov (United States)

    Glaab, Louis J.; Hughes, Monic F.; Parrish, Russell V.; Takallu, Mohammad A.

    2006-01-01

    A flight-test experiment was conducted using the NASA LaRC Cessna 206 aircraft. Four primary flight and navigation display concepts, including baseline and Synthetic Vision System (SVS) concepts, were evaluated in the local area of Roanoke Virginia Airport, flying visual and instrument approach procedures. A total of 19 pilots, from 3 pilot groups reflecting the diverse piloting skills of the GA population, served as evaluation pilots. Multi-variable Discriminant Analysis was applied to three carefully selected and markedly different operating conditions with conventional instrumentation to provide an extension of traditional analysis methods as well as provide an assessment of the effectiveness of SVS displays to effectively transform IMC flight into VMC flight.

  20. Branson: A Mini-App for Studying Parallel IMC, Version 1.0

    Energy Technology Data Exchange (ETDEWEB)

    2017-03-28

    This code solves the gray thermal radiative transfer (TRT) equations in parallel using simple opacities and Cartesian meshes. Although Branson solves the TRT equations it is not designed to model radiation transport: Branson contains simple physics and does not have a multigroup treatment, nor can it use physical material data. The opacities have are simple polynomials in temperature there is a limited ability to specify complex geometries and sources. Branson was designed only to capture the computational demands of production IMC codes, especially in large parallel runs. It was also intended to foster collaboration with vendors, universities and other DOE partners. Branson is similar in character to the neutron transport proxy-app Quicksilver from LLNL, which was recently open-sourced.

  1. Integrated Marketing Communications (IMC) Variables That Influence Perceived Return on Investment (ROI) in Higher Education: Chief Marketing Officers' Perceptions

    Science.gov (United States)

    King, Adrienne L.

    2013-01-01

    This study examines the relationship of the level of Integrated Marketing Communications (IMC) implementation, level of open systems and change in state appropriations on perceived return on investment (ROI) in U.S. public higher education institutions (HEIs). Designed to provide HEI leaders with data to more accurately determine the best IMC…

  2. A Report of Perceptions of Censorship of IMC Materials in 1982-83 from a State-Level Perspective.

    Science.gov (United States)

    Hopkins, Dianne McAfee

    A survey was conducted in August and September 1983 to ascertain the perceptions of state leaders regarding censorship of K-12 instructional media center (IMC) materials during the 1982-83 school year. Of the 53 surveys sent to persons involved with state-level library media programs, 42 responses representing 41 states and one territory were…

  3. Teacher Use of Instructional Materials and Other Matters Related to Special Education IMC/LRC Collections. Theoretical Paper No. 59.

    Science.gov (United States)

    Latham, Glenn

    Presented is the report of a study -- involving 1150 special education teachers and 25 instructional materials centers (IMCs) and learning resource centers (LRCs) -- to investigate the needs for, uses of, and priorities for instructional materials for teaching handicapped children. Listed are three methods of data collection: the use of materials…

  4. Integrated Marketing Communications (IMC) Variables That Influence Perceived Return on Investment (ROI) in Higher Education: Chief Marketing Officers' Perceptions

    Science.gov (United States)

    King, Adrienne L.

    2013-01-01

    This study examines the relationship of the level of Integrated Marketing Communications (IMC) implementation, level of open systems and change in state appropriations on perceived return on investment (ROI) in U.S. public higher education institutions (HEIs). Designed to provide HEI leaders with data to more accurately determine the best IMC…

  5. Ron knockdown and Ron monoclonal antibody IMC-RON8 sensitize pancreatic cancer to histone deacetylase inhibitors (HDACi).

    Science.gov (United States)

    Zou, Yi; Howell, Gillian M; Humphrey, Lisa E; Wang, Jing; Brattain, Michael G

    2013-01-01

    Recepteur d'origine nantais (Ron) is overexpressed in a panel of pancreatic cancer cells and tissue samples from pancreatic cancer patients. Ron can be activated by its ligand macrophage stimulating protein (MSP), thereby activating oncogenic signaling pathways. Crosstalk between Ron and EGFR, c-Met, or IGF-1R may provide a mechanism underlying drug resistance. Thus, targeting Ron may represent a novel therapeutic strategy. IMC-RON8 is the first Ron monoclonal antibody (mAb) entering clinical trial for targeting Ron overexpression. Our studies show IMC-RON8 downmodulated Ron expression in pancreatic cancer cells and significantly blocked MSP-stimulated Ron activation, downstream Akt and ERK phosphorylation, and survivin mRNA expression. IMC-RON8 hindered MSP-induced cell migration and reduced cell transformation. Histone deacetylase inhibitors (HDACi) are reported to target expression of various genes through modification of nucleosome histones and non-histone proteins. Our work shows HDACi TSA and Panobinostat (PS) decreased Ron mRNA and protein expression in pancreatic cancer cells. PS also reduced downstream signaling of pAkt, survivin, and XIAP, as well as enhanced cell apoptosis. Interestingly, PS reduced colony formation in Ron knockdown cells to a greater extent than Ron scramble control cells in colony formation and soft agarose assays. IMC-RON8 could also sensitize pancreatic cancer cells to PS, as reflected by reduced colony numbers and size in combination treatment with IMC-RON8 and PS compared to single treatment alone. The co-treatment further reduced Ron expression and pAkt, and increased PARP cleavage compared to either treatment alone. This study suggests the potential for a novel combination approach which may ultimately be of value in treatment of pancreatic cancer.

  6. Ron knockdown and Ron monoclonal antibody IMC-RON8 sensitize pancreatic cancer to histone deacetylase inhibitors (HDACi.

    Directory of Open Access Journals (Sweden)

    Yi Zou

    Full Text Available Recepteur d'origine nantais (Ron is overexpressed in a panel of pancreatic cancer cells and tissue samples from pancreatic cancer patients. Ron can be activated by its ligand macrophage stimulating protein (MSP, thereby activating oncogenic signaling pathways. Crosstalk between Ron and EGFR, c-Met, or IGF-1R may provide a mechanism underlying drug resistance. Thus, targeting Ron may represent a novel therapeutic strategy. IMC-RON8 is the first Ron monoclonal antibody (mAb entering clinical trial for targeting Ron overexpression. Our studies show IMC-RON8 downmodulated Ron expression in pancreatic cancer cells and significantly blocked MSP-stimulated Ron activation, downstream Akt and ERK phosphorylation, and survivin mRNA expression. IMC-RON8 hindered MSP-induced cell migration and reduced cell transformation. Histone deacetylase inhibitors (HDACi are reported to target expression of various genes through modification of nucleosome histones and non-histone proteins. Our work shows HDACi TSA and Panobinostat (PS decreased Ron mRNA and protein expression in pancreatic cancer cells. PS also reduced downstream signaling of pAkt, survivin, and XIAP, as well as enhanced cell apoptosis. Interestingly, PS reduced colony formation in Ron knockdown cells to a greater extent than Ron scramble control cells in colony formation and soft agarose assays. IMC-RON8 could also sensitize pancreatic cancer cells to PS, as reflected by reduced colony numbers and size in combination treatment with IMC-RON8 and PS compared to single treatment alone. The co-treatment further reduced Ron expression and pAkt, and increased PARP cleavage compared to either treatment alone. This study suggests the potential for a novel combination approach which may ultimately be of value in treatment of pancreatic cancer.

  7. Wettability and interface layer characteristics of Sn-3.5Ag solder alloy with tilting copper and nickel substrates%Sn-3.5Ag合金在Cu,Ni倾斜基板的润湿及界面特性

    Institute of Scientific and Technical Information of China (English)

    战亚鹏; 徐红艳; 王晨钰; 周舟; 袁章福; 张军玲; 赵宏欣

    2011-01-01

    Good wettability is a key factor for excellent solder. The study of wetting behavior is an important step in the characterization of solder alloys and also provides basic physicochemical data for design and development of composite lead-free solder alloys. As operatings in various industrial processes were often on tilting surface, the study of wetting behavior on the inclined substrate could better reflect the actual situation. Sessile drop method was employed to investigate the wetting behavior of a new Sn-3.5 Ag solder alloy on Cu and Ni substrates under Ar-H2 flow in the temperature (494-744) K. The result indicate that in (494~744) K, the contact angle between Sn-3.5 Ag and Cu substrate was 139.2°~33.3°, the contact angle hysteresis was 82.1°~47.8°. In (494-744) K, the contact angle between Sn-3.5 Ag and Ni substrate was 140.8°~41.5°, the contact angle hysteresis was 92°~60.9°. Among these solder alloys studied, the wettability of Sn-3.5 Ag alloy to the Cu substrates was excellent and reactivity wettability. Intermetallics(IMC) at the Sn-3.5 Ag/Cu interface are identified by EPMA analysis as Cu6Sn5 adjacent to the solder and Cu3Sn adjacent to the Cu substrate, respectively. The configuration of the triple line of Sn-3.5 Ag/Cu is discussed by the description of equilibrium. The calculated results based on experimental values of tension balances along each of the three interfaces at this final state show good agreement with theoretical analysis. The wettability of Sn-3.5 Ag alloy to the Ni substrates was excellent and reactivity wettability..%良好的润湿性是优质焊料的重要指标,同时也可以为复合无铅焊料的开发提供必要的研究基础。而工业过程中的操作表面往往是倾斜的,因此,研究倾斜状态下的润湿特性更能反映实际情况。本文采用静滴法研究了不同温度下Sn-3.5Ag合金熔体在Cu,Ni材料水平基板和倾斜基板上的润湿行为与界面相互作用,分析了润

  8. Scientific Opinion on the substantiation of a health claim related to SYNBIO®, a combination of Lactobacillus rhamnosus IMC 501® and Lactobacillus paracasei IMC 502®, and maintenance of normal defecation pursuant to Article 13(5) of Regulation (EC) No

    DEFF Research Database (Denmark)

    Tetens, Inge

    on the scientific substantiation of a health claim related to SYNBIO®, a combination of Lactobacillus rhamnosus IMC 501® and Lactobacillus paracasei IMC 502®, and maintenance of normal defecation. The Panel considers that the food, SYNBIO®, which is the subject of the health claim, is sufficiently characterised...... for an effect of SYNBIO® on the maintenance of normal defecation in humans, studies which investigated the presence of L. rhamnosus IMC 501® and L. paracasei IMC 502® in the faeces of participants who consumed foods enriched with these strains were not considered by the Panel. The Panel concludes that a cause...

  9. Genetic insights into pyralomicin biosynthesis in Nonomuraea spiralis IMC A-0156.

    Science.gov (United States)

    Flatt, Patricia M; Wu, Xiumei; Perry, Steven; Mahmud, Taifo

    2013-05-24

    The biosynthetic gene cluster for the pyralomicin antibiotics has been cloned and sequenced from Nonomuraea spiralis IMC A-0156. The 41 kb gene cluster contains 27 ORFs predicted to encode all of the functions for pyralomicin biosynthesis. This includes nonribosomal peptide synthetases (NRPS) and polyketide synthases (PKS) required for the formation of the benzopyranopyrrole core unit, as well as a suite of tailoring enzymes (e.g., four halogenases, an O-methyltransferase, and an N-glycosyltransferase) necessary for further modifications of the core structure. The N-glycosyltransferase is predicted to transfer either glucose or a pseudosugar (cyclitol) to the aglycone. A gene cassette encoding C7-cyclitol biosynthetic enzymes was identified upstream of the benzopyranopyrrole-specific ORFs. Targeted disruption of the gene encoding the N-glycosyltransferase, prlH, abolished pyralomicin production, and recombinant expression of PrlA confirms the activity of this enzyme as a sugar phosphate cyclase involved in the formation of the C7-cyclitol moiety.

  10. Practitioners’ view of the role of OOH advertising media in IMC campaigns

    Directory of Open Access Journals (Sweden)

    A. Therese Roux

    2016-12-01

    Full Text Available Despite the traction that contemporary out-of-home advertising has gained in the global media landscape, there are still some ambiguities regarding the contribution of this medium in the context of integrated marketing communication. Previous studies have examined consumers’ responses to different out-of-home advertising media types; however, little attention has been paid to how they could contribute to an overall integrated marketing communication (IMC program. The purpose of the study was, therefore, to explore a practitioner’s view of the role of out-of-home advertising media in an integrated marketing communication campaign. Investigating knowledgeable practitioners’ perspectives and practices helped to reveal novel media planning techniques applied by specialists in the field and contributed to the limited theory on out-of-home advertising media planning. The three roles performed by out-of-home advertising media within this context: support; lead; or even as the only media, were clarified. Some unique media tactics to reach marketing communication objectives on cognitive, affective or behavioural levels and direction for future research were also proposed.

  11. 用于二阶加纯滞后过程的IMC-PID控制器的研究%Study of IMC-based PID controller for a second order lag process with dead time

    Institute of Scientific and Technical Information of China (English)

    龚剑平; 王连伟; 游浩

    1999-01-01

    研究了用于二阶加纯滞后过程(SOPDT)的IMC-PID控制系统, 对纯滞后采用一阶或非对称二阶Pade近似, 给出了结构均为简单的二阶IMC-PID控制器, 且只需调整一个参数. 结果表明: 与采用其它经典PID控制器参数整定方法的系统相比, 控制系统的性能指标和鲁棒性得到了很大的改善.

  12. Effect of buckwheat flour and oat bran on growth and cell viability of the probiotic strains Lactobacillus rhamnosus IMC 501®, Lactobacillus paracasei IMC 502® and their combination SYNBIO®, in synbiotic fermented milk.

    Science.gov (United States)

    Coman, Maria Magdalena; Verdenelli, Maria Cristina; Cecchini, Cinzia; Silvi, Stefania; Vasile, Aida; Bahrim, Gabriela Elena; Orpianesi, Carla; Cresci, Alberto

    2013-10-15

    Fermented foods have a great significance since they provide and preserve large quantities of nutritious foods in a wide diversity of flavors, aromas and texture, which enrich the human diet. Originally fermented milks were developed as a means of preserving nutrients and are the most representatives of the category. The first aim of this study was to screen the effect of buckwheat flour and oat bran as prebiotics on the production of probiotic fiber-enriched fermented milks, by investigating the kinetics of acidification of buckwheat flour- and oat bran-supplemented milk fermented by Lactobacillus rhamnosus IMC 501®, Lactobacillus paracasei IMC 502® and their 1:1 combination named SYNBIO®. The probiotic strains viability, pH and sensory characteristics of the fermented fiber-enriched milk products, stored at 4 °C for 28 days were also monitored. The results showed that supplementation of whole milk with the tested probiotic strains and the two vegetable substrates results in a significant faster lowering of the pH. Also, the stability of L. rhamnosus IMC 501®, L. paracasei IMC 502® and SYNBIO® during storage at 4 °C for 28 days in buckwheat flour- and oat bran-supplemented samples was remarkably enhanced. The second aim of the study was to develop a new synbiotic product using the best combination of probiotics and prebiotics by promoting better growth and survival and be acceptable to the consumers with high concentration of probiotic strain. This new product was used to conduct a human feeding trial to validate the fermented milk as a carrier for transporting bacterial cells into the human gastrointestinal tract. The probiotic strains were recovered from fecal samples in 40 out of 40 volunteers fed for 4 weeks one portion per day of synbiotic fermented milk carrying about 10(9) viable cells. © 2013.

  13. Pondering on How to Introduce IMC into Chinese Enterprises%对我国企业导入IMC的思考

    Institute of Scientific and Technical Information of China (English)

    张莹

    2004-01-01

    IMC(整合营销传播)带来了营销方式的变革,是企业获取可持续竞争优势的重要选择.然而,我国企业在导入IMC过程中遇到了诸如对利害关系者重视不够、营销传播管理者水平不高等障碍.因此,必须采取建立消费者数据库、搭建现代客户导向型企业组织结构等策略正确导入IMC,真正发挥其效力.

  14. Targeting FMS-related tyrosine kinase receptor 3 with the human immunoglobulin G1 monoclonal antibody IMC-EB10.

    Science.gov (United States)

    Youssoufian, Hagop; Rowinsky, Eric K; Tonra, James; Li, Yiwen

    2010-02-15

    FMS-related tyrosine kinase receptor 3 (FLT3) is a class III receptor tyrosine kinase that holds considerable promise as a therapeutic target in hematologic malignancies. Current efforts directed toward the development of small-molecule tyrosine kinase inhibitors of FLT3 may be limited by off-target toxicities and the development of drug resistance. Target-specific antibodies could overcome these hurdles and provide additional mechanisms to enhance the antitumor efficacy of FLT3 inhibitors. IMC-EB10 is a novel antibody directed against FLT3. The binding of IMC-EB10 to FLT3 results in antiproliferative effects in vitro and in mouse models engrafted with human leukemia cells that harbor wild-type or constitutively activated FLT3. Future clinical trials will test these notions formally and will identify the most appropriate opportunities for this member of a new generation of antileukemic therapies.

  15. Limitations of Feedback, Feedforward and IMC Controller for a First Order Non-Linear Process with Dead Time

    Directory of Open Access Journals (Sweden)

    Maruthai Suresh

    2010-10-01

    Full Text Available A nonlinear process, the heat exchanger whose parameters vary with respect to the process variable, is considered. The time constant and gain of the chosen process vary as a function of temperature. The limitations of the conventional feedback controller tuned using Ziegler-Nichols settings for the chosen process are brought out. The servo and regulatory responses through simulation and experimentation for various magnitudes of set-point changes and load changes at various operating points with the controller tuned only at a chosen nominal operating point are obtained and analyzed. Regulatory responses for output load changes are studied. The efficiency of feedforward controller and the effects of modeling error have been brought out. An IMC based system is presented to understand clearly how variations of system parameters affect the performance of the controller. The present work illustrates the effectiveness of Feedforward and IMC controller.

  16. 电场作用下SnAgCu焊点界面化合物生长行为研究%Research on Intermetallic Compound Growth Behavior of SnAgCu Solder Joint Under Electric Field

    Institute of Scientific and Technical Information of China (English)

    程光辉; 王要利; 赵向飞; 郭江

    2015-01-01

    研究了电场对Sn3.0Ag0.5Cu焊点界面间化合物(IMC)的影响.结果表明:电流会对试样IMC厚度起促进作用,IMC生长速度随着电流的增大呈递增趋势,且大电流对IMC生长作用明显,小电流对IMC生长的促进作用有限.IMC由Cu6Sn5和Cu3Sn共同组成,呈扇贝状生长.

  17. Sveobuhvatno istraživanje spojeva bakrenih cijevi izrađenih čvrstim lemljenjem

    OpenAIRE

    Koleňák, Roman; Provazník, Martin; Koleňáková, Monika

    2013-01-01

    Cilj je ovoga rada bio procijeniti tehnološku lemljivost bakrenih cijevi električnim otporom. Lemljenje električnim otporom je alternativa klasičnom zagrijavanju plamenom. Vrijeme taljenja eksperimentalnih lemila određeno je DSC analizom. Ustanovljene su najčešće greške zalemljenih spojeva i otkriveni faktori koji su ih uzrokovali. Primijećene su faze Cu3Sn i Cu6Sn5 na rubovima analiziranih spojeva. Prosječna debljina IMC (intermetalnih spojeva) na uzorcima izrađenim čvrstim lemljenjem bila ...

  18. Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite.

    Science.gov (United States)

    Poulin, Benoit; Patzewitz, Eva-Maria; Brady, Declan; Silvie, Olivier; Wright, Megan H; Ferguson, David J P; Wall, Richard J; Whipple, Sarah; Guttery, David S; Tate, Edward W; Wickstead, Bill; Holder, Anthony A; Tewari, Rita

    2013-01-01

    The phylum Apicomplexa comprises over 5000 intracellular protozoan parasites, including Plasmodium and Toxoplasma, that are clinically important pathogens affecting humans and livestock. Malaria parasites belonging to the genus Plasmodium possess a pellicle comprised of a plasmalemma and inner membrane complex (IMC), which is implicated in parasite motility and invasion. Using live cell imaging and reverse genetics in the rodent malaria model P. berghei, we localise two unique IMC sub-compartment proteins (ISPs) and examine their role in defining apical polarity during zygote (ookinete) development. We show that these proteins localise to the anterior apical end of the parasite where IMC organisation is initiated, and are expressed at all developmental stages, especially those that are invasive. Both ISP proteins are N-myristoylated, phosphorylated and membrane-bound. Gene disruption studies suggest that ISP1 is likely essential for parasite development, whereas ISP3 is not. However, an absence of ISP3 alters the apical localisation of ISP1 in all invasive stages including ookinetes and sporozoites, suggesting a coordinated function for these proteins in the organisation of apical polarity in the parasite.

  19. Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite

    Directory of Open Access Journals (Sweden)

    Benoit Poulin

    2013-09-01

    The phylum Apicomplexa comprises over 5000 intracellular protozoan parasites, including Plasmodium and Toxoplasma, that are clinically important pathogens affecting humans and livestock. Malaria parasites belonging to the genus Plasmodium possess a pellicle comprised of a plasmalemma and inner membrane complex (IMC, which is implicated in parasite motility and invasion. Using live cell imaging and reverse genetics in the rodent malaria model P. berghei, we localise two unique IMC sub-compartment proteins (ISPs and examine their role in defining apical polarity during zygote (ookinete development. We show that these proteins localise to the anterior apical end of the parasite where IMC organisation is initiated, and are expressed at all developmental stages, especially those that are invasive. Both ISP proteins are N-myristoylated, phosphorylated and membrane-bound. Gene disruption studies suggest that ISP1 is likely essential for parasite development, whereas ISP3 is not. However, an absence of ISP3 alters the apical localisation of ISP1 in all invasive stages including ookinetes and sporozoites, suggesting a coordinated function for these proteins in the organisation of apical polarity in the parasite.

  20. Report by the International Space Station (ISS) Management and Cost Evaluation (IMCE) Task Force

    Science.gov (United States)

    Young, A. Thomas; Kellogg, Yvonne (Technical Monitor)

    2001-01-01

    The International Space Station (ISS) Management and Cost Evaluation Task Force (IMCE) was chartered to conduct an independent external review and assessment of the ISS cost, budget, and management. In addition, the Task Force was asked to provide recommendations that could provide maximum benefit to the U.S. taxpayers and the International Partners within the President's budget request. The Task Force has made the following principal findings: (1) The ISS Program's technical achievements to date, as represented by on-orbit capability, are extraordinary; (2) The Existing ISS Program Plan for executing the FY 02-06 budget is not credible; (3) The existing deficiencies in management structure, institutional culture, cost estimating, and program control must be acknowledged and corrected for the Program to move forward in a credible fashion; (4) Additional budget flexibility, from within the Office of Space Flight (OSF) must be provided for a credible core complete program; (5) The research support program is proceeding assuming the budget that was in place before the FY02 budget runout reduction of $1B; (6) There are opportunities to maximize research on the core station program with modest cost impact; (7) The U.S. Core Complete configuration (three person crew) as an end-state will not achieve the unique research potential of the ISS; (8) The cost estimates for the U.S.-funded enhancement options (e.g., permanent seven person crew) are not sufficiently developed to assess credibility. After these findings, the Task Force has formulated several primary recommendations which are published here and include: (1) Major changes must be made in how the ISS program is managed; (2) Additional cost reductions are required within the baseline program; (3) Additional funds must be identified and applied from the Human Space Flight budget; (4) A clearly defined program with a credible end-state, agreed to by all stakeholders, must be developed and implemented.

  1. Adhesion of Streptococcus sanguinis to glass surfaces measured by isothermal microcalorimetry (IMC).

    Science.gov (United States)

    Hauser-Gerspach, Irmgard; de Freitas, Patricia Scandiucci; Dan Daniels, A U; Meyer, Jürg

    2008-04-01

    Bacterial adhesion is the first step in the development of the oral biofilm, called dental plaque. Plaque is the cause of caries, periodontal diseases, and periimplantitis. Investigations of dental plaque, including bacterial adhesion, employ various in vivo and in vitro models using microscopic methods. Microcalorimetry offers another direct approach. The model organism Streptococcus sanguinis is one of the first colonizers adhering to the saliva-coated human tooth surfaces or dental materials within minutes after tooth cleaning. TAM III thermostats, equipped with microcalorimeters, were used for isothermal microcalorimetric (IMC) measurements of heat production as a function of time, expressed by power-time (p-t) curves. Continuous measurements of heat production of growing S. sanguinis cells showed their overall metabolic activity and were highly reproducible. For the adhesion experiments the bacteria were allowed to adhere to different amounts of glass beads. Growing S. sanguinis cells produced a characteristic p-t curve with a maximum of 500 microW at 4.5 h when reaching 10(9) cells ml(-1). The same number of stationary S. sanguinis cells, suspended in PBS produced only approximately 30 microW at 0.5 h due to adhesion. But the amount of heat increased with available glass surface area, indicating that a portion of the heat of adhesion was measured. Similar results were obtained with stationary S. sanguinis cells suspended in human saliva. This study shows that microcalorimetric evaluation of initial bacterial adhesion is indeed possible and may become a rapid, reproducible screening method to study adhesion of different bacteria to different dental materials or to modified surfaces.

  2. Al and Si Alloying Effect on Solder Joint Reliability in Sn-0.5Cu for Automotive Electronics

    Science.gov (United States)

    Hong, Won Sik; Oh, Chulmin; Kim, Mi-Song; Lee, Young Woo; Kim, Hui Joong; Hong, Sung Jae; Moon, Jeong Tak

    2016-08-01

    To suppress the bonding strength degradation of solder joints in automotive electronics, we proposed a mid-temperature quaternary Pb-free Sn-0.5Cu solder alloy with minor Pd, Al, Si and Ge alloying elements. We manufactured powders and solder pastes of Sn-0.5Cu-(0.01,0.03)Al-0.005Si-(0.006-0.007)Ge alloys (T m = 230°C), and vehicle electronic control units used for a flame-retardant-4 printed circuit board with an organic solderability preservative finish were assembled by a reflow soldering process. To investigate the degradation properties of solder joints used in engine compartments, thermal cycling tests were conducted from -40°C to 125°C (10 min dwell) for 1500 cycles. We also measured the shear strength of the solder joints in various components and observed the microstructural evolution of the solder joints. Based on these results, intermetallic compound (IMC) growth at the solder joints was suppressed by minor Pd, Al and Si additions to the Sn-0.5Cu alloy. After 1500 thermal cycles, IMC layers thicknesses for 100 parts per million (ppm) and 300 ppm Al alloy additions were 6.7 μm and 10 μm, compared to the as-reflowed bonding thicknesses of 6 μm and 7 μm, respectively. Furthermore, shear strength degradation rates for 100 ppm and 300 ppm Al(Si) alloy additions were at least 19.5%-26.2%. The cause of the improvement in thermal cycling reliability was analyzed using the (Al,Cu)-Sn, Si-Sn and Al-Sn phases dispersed around the Cu6Sn5 intermetallic at the solder matrix and bonding interfaces. From these results, we propose the possibility of a mid-temperature Sn-0.5Cu(Pd)-Al(Si)-Ge Pb-free solder for automotive engine compartment electronics.

  3. Evolution of Intermetallic Compounds between Sn-0.3Ag-0.7Cu Low-silver Lead-free Solder and Cu Substrate during Thermal Aging

    Institute of Scientific and Technical Information of China (English)

    Niwat Mookam; Kannachai Kanlayasiri

    2012-01-01

    The growth, transformation, and lattice structure of intermetallic compounds formed between Sn-0.3Ag-0.7Cu lead-free solder and copper substrate were investigated. Dip soldering was used to initiate the reaction between the solder and substrate. An r/-Cu6Sn5 intermetallic phase possessing a hexagonal lattice structure was found at the as-soldered interface. Thermal aging at a number of conditions resulted in the formation of a CuaSn intermetallic phase between the Cu6Sn5 layer and the copper substrate, e-Cu3Sn with an orthorhombic lattice structure was found together with hexagonal CusSn. Subsequently, the activation energies of the intermetallic phases were calculated and compared to results obtained from the literature. The comparison showed that good agreement existed between the findings from this study and literature data within a similar temperature range.

  4. Effects of Fe and Bi Minor Alloying on Mechanical, Thermal, and Microstructural Properties of Sn-0.7Cu Solder Alloy

    Science.gov (United States)

    Mahdavifard, M. H.; Sabri, M. F. M.; Said, S. M.; Shnawah, D. A.; Badruddin, I. A.; Rozali, S.

    2016-07-01

    The effects of adding 0.05 wt.% Fe and 1 wt.% or 2 wt.% Bi on the mechanical, thermal, and microstructural properties of Sn-0.7Cu solder alloy have been investigated. Addition of 0.05% Fe did not change the morphology of the microstructure, so the mechanical properties and melting behavior remained unchanged. Analyses showed that, besides inclusion of Fe in Cu6Sn5 intermetallic compound (IMC), a few FeSn2 IMCs formed in interdendritic regions. On the other hand, addition of 2% Bi to Sn-0.7Cu-0.05Fe alloy increased the yield strength by 97%, from 19.7 MPa to 38.84 MPa. This is because addition of Bi degraded interdendritic regions by reducing the amount of Cu6Sn5 IMC particles and refining primary β-Sn dendrites. Furthermore, differential scanning calorimetry indicated that Bi reduced the melting temperature by 4°C from 232.2°C to 228.1°C for the 2% Bi alloy.

  5. Effect of phase morphologies on the mechanical properties of babbitt-bronze composite interfaces

    Science.gov (United States)

    Liaw, P. K.; Gungor, M. N.; Logsdon, W. A.; Ijiri, Y.; Taszarek, B. J.; Frohlich, S.

    1990-02-01

    Interfaces of two different babbitt-bronze composites were tested ultrasonically and then were fractured using the Chalmers test method. The primary distinction between the two composites was in the copper content. Use of less copper in the babbitt resulted in interfaces with higher strength, lower ductility, less cracking, and less unbonded area. The differences appeared to stem from the structure of the intermetallic compounds found at the interface, namely, the Cu3Sn and the Cu6Sn5 layers. The low-copper composite failed within a thick, dendrite-like Cu6Sn5 layer, while the high-copper one separated at the interface between a smooth Cu6Sn5 layer and the babbitt metal. The rough interface morphology seemed responsible for the low-copper composite’s increased strength. The correlation between mechanical and ultrasonic properties was poor for the low-copper composite but excellent for the high-copper one. These results suggest that interface morphology can significantly affect mechanical as well as ultrasonic properties.

  6. Tsuwalhkalh Ti Tmicwa (The Land is Ours): Stat'imc Self-Determination in the Face of Large-Scale Hydro-electric Development

    Science.gov (United States)

    Moritz, Sarah Carmen

    In Canada, First Nations asserting authority over their lands are developing diverse strategies to overcome the state''s dogmatic insistence on jurisdictional sovereignty. This movement corresponds to the wider context of the challenges faced by indigenous people to use their own ways of knowing to resist or reformulate legal doctrines and political tenets based on colonial power. Interior Salish Stat'imc people identify themselves through a strong and ongoing social relationship with Sataqwa7, the Fraser River, and the "Valley of Plenty"---now known as the flooded Bridge River Valley---maintained through Stat'imc knowledge and cultural practice and demonstrated by talk of '"the Stat'imc right to fish" and Tsuwalhkalh Ti Tmicwa (The Land is Ours). Stat'imc fishers are prepared to contest and resist any regulatory system that is understood to impact this right to fish while they advocate their own ways of sustainable fishing and water management. Based on ethnographic research in collaboration with Stat'imc people, this thesis explores some of these often successful contestations especially in the context of increasing territorial governance and by example of the rapidly transforming relationship between Stat'imc, BC Hydro and the Province of BC. Interior Salish Stat'imc people are currently navigating through a significant phase of increasing jurisdiction and authority and recognition of (unsettled) territorial property relationships. This very dynamic process is marked by strategic collaborations, compensation for 'infringements' on St'a'imc Title and Rights, and conservation efforts to protect their home. An important example is the changing relationship between Stat'imc people and BC Hydro---a relationship between two groups with radically different cultures and agendas: Stat'imc people in a struggle for self-determination, social justice and cultural survival and BC Hydro, a corporate culture, with the agenda to provide hydro-electric power to BC, maintain

  7. Intermetallic compound layer growth kinetics in non-lead bearing solders

    Energy Technology Data Exchange (ETDEWEB)

    Vianco, P.T.; Kilgo, A.C.; Grant, R.

    1995-04-01

    The introduction of alternative, non-lead bearing solders into electronic assemblies requires a thorough investigation of product manufacturability and reliability. Both of these attributes can be impacted by the excessive growth of intermetallic compound (IMC) layers at the solder/substrate interface. An extensive study has documented the stoichiometry and solid state growth kinetics of IMC layers formed between copper and the lead-free solders: 96.5Sn-3.5Ag (wt.%), 95Sn-5Sb, 100Sn, and 58Bi-42Sn. Aging temperatures were 70--205 C for the Sn-based solders and 55--120 C for the Bi-rich solder. Time periods were 1--400 days for all of the alloys. The Sn/Cu, Sn-Ag/Cu, and Sn-Sb/Cu IMC layers exhibited sub-layers of Cu{sub 6}Sn{sub 5} and Cu{sub 3}Sn; the latter composition was present only following prolonged aging times or higher temperatures. The total layer growth exhibited a time exponent of n = 0.5 at low temperatures and a value of n = 0.42 at higher temperatures in each of the solder/Cu systems. Similar growth kinetics were observed with the low temperature 58Bi-42Sn solder; however, a considerably more complex sub-layer structure was observed. The kinetic data will be discussed with respect to predicting IMC layer growth based upon solder composition.

  8. Sensitivity analysis of helicopter IMC decelerating steep approach and landing performance to navigation system parameters. [Instrument Meteorological Conditions

    Science.gov (United States)

    Karmali, M. S.; Phatak, A. V.; Bull, J. S.; Peach, L. L.; Demko, P. S.

    1984-01-01

    The present investigation is concerned with a sensitivity analysis of the Decelerated Steep Approach and Landing (DSAL) maneuver to on-board and ground-based navigation system parameters. The Instrument Meteorological Conditions (IMC) DSAL maneuver involves decelerating to zero range rate while tracking the localizer and glideslope. The considered study investigated the performance of the navigation systems using Constant Deceleration Profile (CDP) guidance and a six degrees glideslope trajectory. A closed-loop computer simulation of the UH1H helicopter DSAL system was developed for the sensitivity analysis. Conclusions on system performance parameter sensitivity are discussed.

  9. Design of Dynamic Quantizers for 2-DOF IMC and Its Application to the Temperature Control of a Heat Plate

    Science.gov (United States)

    Okajima, Hiroshi; Matsunaga, Nobutomo; Kawaji, Shigeyasu

    It is well known that plants with dead-time are difficult to controll by using traditional control methods. For this, some controllers with dead-time have been proposed for the systems with dead-time, e.g. Internal Model Control (IMC) and the Smith-method. However, these controllers cause another problem, i.e. it would be difficult to realize the dead-time component in controller because of the memory limit of micro control unit (MCU). The sampling time has to be large in applications to the plant with large dead-time when each data size is sufficiently kept. Hence, a trade-off between the sampling time and the maximum quantization error exists by the memory limit. In this paper, a design method of dynamic quantizers is proposed for achieving small quantization error for control systems in MCU. The effectiveness of the proposed method is shown by numerical examples. Moreover, the proposed method is applied to a temperature control of a heat plate. Since the input-output relation of the temperature control system can be written with dead-time, 2-DOF IMC is introduced for this system. It is verified that the output with the proposed quantizer approximates the desired output under the memory limit.

  10. IMC-A12, a human IgG1 monoclonal antibody to the insulin-like growth factor I receptor.

    Science.gov (United States)

    Rowinsky, Eric K; Youssoufian, Hagop; Tonra, James R; Solomon, Phillip; Burtrum, Douglas; Ludwig, Dale L

    2007-09-15

    Targeted monoclonal antibody therapy is an important strategy in cancer therapeutics. Among the most promising characteristics of therapeutic targets are those that modulate the growth and survival of malignant neoplasms and their sensitivity to anticancer therapies. The insulin-like growth factor-I receptor (IGF-IR) is overexpressed in many types of solid and hematopoietic malignancies, and has been implicated as a principal cause of heightened proliferative and survival signaling. IGF-IR has also been shown to confer resistance to cytotoxic, hormonal, and targeted therapies, suggesting that therapeutics targeting IGF-IR may be effective against a broad range of malignancies. IMC-A12 (ImClone Systems Incorporated), a fully human monoclonal IgG1 antibody that binds with high affinity to the IGF-IR, inhibits ligand-dependent receptor activation and downstream signaling. IMC-A12 also mediates robust internalization and degradation of the IGF-IR. In human tumor xenograft models, IGF-IR blockade by IMC-A12 results in rapid and profound growth inhibition of cancers of the breast, lung, colon, and pancreas, and many other neoplasms. Although promising single-agent activity has been observed, the most impressive effects of targeting the IGF-IR with IMC-A12 have been noted when this agent was combined with cytotoxic agents or other targeted therapeutics. The results with IMC-A12 to date suggest that it may be an effective therapeutic in a diverse array of oncologic indications.

  11. Surface Morphology of Sn-Rich Solder Interconnects After Electrical Loading

    Science.gov (United States)

    Zhu, Q. S.; Liu, H. Y.; Wang, Z. G.; Shang, J. K.

    2012-04-01

    Morphological changes from electromigration were examined on microsized Sn-Ag-Cu, pure Sn, and single-crystal Sn solder interconnects. It was found that both grain structure and alloying had a strong influence on the form of electromigration damage. In polycrystal Sn, grain boundary grooves were the primary form of electromigration damage, while in single-crystal Sn interconnects wavy surface relief appeared following electromigration. Alloying with Ag and Cu encouraged formation of Sn hillocks and Cu6Sn5 intermetallic compound (IMC) segregation. The grain boundary grooves were related to the divergence of the vacancy concentration at grain boundaries, which induced Sn grain tilting or sliding. Removal of the grain boundaries in the single-crystal interconnect made surface diffusion the primary electromigration mechanism, resulting in wavy surface relief after long electromigration time. In Sn-Ag-Cu alloy, directional flow of Cu caused Cu6Sn5 IMC segregation, which produced large compressive stress, driving the stressed grains to grow into hillocks.

  12. Microstructural behavior of iron and bismuth added Sn-1Ag-Cu solder under elevated temperature aging

    Science.gov (United States)

    Ali, Bakhtiar; Sabri, Mohd Faizul Mohd; Jauhari, Iswadi

    2016-07-01

    An extensive study was done to investigate the microstructural behavior of iron (Fe) and bismuth (Bi) added Sn-1Ag-0.5Cu (SAC105) under severe thermal aging conditions. The isothermal aging was done at 200 °C for 100 h, 200 h, and 300 h. Optical microscopy with cross-polarized light revealed that the grain size significantly reduces with Fe/Bi addition to the base alloy SAC105 and remains literally the same after thermal aging. The micrographs of field emission scanning electron microscopy (FESEM) with backscattered electron detector and their further analysis via imageJ software indicated that Fe/Bi added SAC105 showed a significant reduction in the IMCs size (Ag3Sn and Cu6Sn5), especially the Cu6Sn5 IMCs, as well as β-Sn matrix and a refinement in the microstructure, which is due to the presence of Bi in the alloys. Moreover, their microstructure remains much more stable under severe thermal aging conditions, which is because of the presence of both Fe and Bi in the alloy. The microstructural behavior suggests that Fe/Bi modified SAC105 would have much improved reliability under severe thermal environments. These modified alloys also have relatively low melting temperature and low cost.

  13. Design and Implementation of Pulp Level Control in Flotation Based on IMC-PID%浮选矿浆液位过程的IMC-PID设计与实现

    Institute of Scientific and Technical Information of China (English)

    陈华; 陈夕松

    2011-01-01

    浮选过程是选矿生产中的关键环节,其液位要求严格控制以保证金属回收率.采用一种基于内模控制(IMC)设计的PID控制器(IMC—PID)来实现选矿浮选矿浆液位的自动控制,具有结构简单、整定参数少、鲁棒性强等优点.介绍了IMC-PID的基本原理和设计步骤,给出了液位控制系统的具体实现.应用表明,基于IMC—PID的浮选液住控制系统提高了浮选的金属回收率,保证了精矿品位,具有良好的推广价值.%Flotation is a key process in mineral processing production, in which flotation level must be strictly controlled to ensure high metal recovery rate. A PID controller ([MC-PID) which is designed based on Internal Model Control(IMC) is applied to bring flotation level under automatic control. The model has such advantages as simple structure, few adjustable parameters and strong robustness. Moreover, the basic principle and design method of IMC-PID are introduced, and a flotation level control system is presented. The practical application indicates that the system has improved the metal recovery rate, which ensures fine quality of ore grade, thus having broad implications.

  14. Analysis of Robustness of PID-GPC Based on IMC Structure%基于IMC结构的PID-GPC的鲁棒性分析

    Institute of Scientific and Technical Information of China (English)

    陈增强; 毛宗星; 杜升之; 孙青林; 袁著祉

    2003-01-01

    Proportion integral differential generalized predictive control(PID-GPC), a new type of generalizedpredictive control(GPC) is introduced, and its quality is analyzed with internal model control (IMC). A veryimportant characteristic, which distinguishes GPC from ordinary IMC, and the robust effect are found. At thesame time, a robust region is obtained according to the control laws, so that the defect that the robust analysiscould be carried out only with stable models is overcome. It is verified that the robustness of PID-GPC is strongerthan general GPC.

  15. Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers.

    Science.gov (United States)

    Herbst, Roy S; Langer, Corey J

    2002-02-01

    Epidermal growth factor receptor is one of four receptors critical to cellular proliferation, differentiation, and survival, and is widely expressed in malignant tissue, particularly in squamous cell carcinoma of the head and neck. Expression has been associated with malignant progression, inhibition of apoptosis, neoplastic angiogenesis, enhanced metastatic potential, and both chemoresistance and radioresistance. IMC-C225 is a chimeric monoclonal antibody that targets extracellular epidermal growth factor receptor; it has shown both in vitro and in vivo antitumor activity in tumor cells lines expressing epidermal growth factor receptor, including heightened radiation response in vitro in cultured human squamous cell carcinoma and enhancement of taxane- and platinum-induced cytotoxicity in non-small cell lung cancer xenografts. In A431 head and neck squamous cell xenografts, IMC-C225 administered both before and after radiation therapy yields a radiation enhancement factor of 3.62, attributable to both tumor necrosis and antiangiogenesis. In phase I pharmacokinetic studies, IMC-C225 has a long half-life, lending itself to convenient weekly administration. It has shown a favorable toxicity profile, limited primarily to allergic and dermatologic reactions, the latter characterized by a self-limited, sterile, acneiform rash. Anaphylaxis is rare. Standard treatment entails a loading dose of 400 mg/m(2) at week 1, followed by a maintenance dose of 250 mg/m(2) weekly. An ongoing phase III international multicenter, randomized study in locally advanced squamous cell carcinoma of the head and neck is evaluating therapeutic radiation therapy, either alone or in conjunction with IMC-C225. In a pilot trial, six of nine patients with platinum-exposed squamous cell carcinoma of the head and neck exhibited objective response. In an ongoing phase II trial in patients with stable or progressive disease on platinum-based therapy, the preliminary response rate is approximately 20

  16. Interfacial Reactions in the Ni/Sn- xZn/Cu Sandwich Couples

    Science.gov (United States)

    Yen, Yee-Wen; Lin, Chung-Yung; Lai, Mei-Ting; Chen, Wan-Ching

    2016-01-01

    The interfacial reactions in Ni/Sn- xZn/Cu sandwich couples which were reflowed at 270°C for 1 h and then aged at 160°C for 1-1000 h were investigated. When the 1000- μm-thick Sn-Zn alloy reacted with Ni and Cu in this couple, the results indicated that the (Ni, Cu)3Sn4, (Ni, Cu)5Zn21, and Ni5Zn21 phases were formed at Sn-1Zn/Ni, Sn-5Zn/Ni, and Sn-9Zn/Ni interfaces for 1 h reflowing, respectively. After 1000 h aging, each intermetallic compound (IMC) was converted to (Cu, Ni, Zn)6Sn5, (Ni, Cu, Sn)5Zn21/Ni5Zn21, and Ni5Zn21 (two layers) phases in the related couples. On the Cu side, the Cu6Sn5 phase in the Sn-1Zn/Cu interface and the Cu5Zn8 phase in the Sn-5Zn/Cu and Sn-9Zn/Cu interfaces were observed when the couple was reflowed at 270°C for 1 h. After 100 h aging, the (Cu, Ni, Zn)6Sn5, Cu5Zn8/(Cu, Zn)6Sn5, and Cu5Zn8 phases were formed at the Sn-1Zn/Cu, Sn-5Zn/Cu and Sn-9Zn/Cu interfaces. When the Sn-Zn alloy thickness was decreased to 500 μm, the (Cu, Ni, Zn)6Sn5 phase at the Sn-1Zn/Ni interface and the (Ni, Cu, Sn)5Zn21 phase at the Sn-5Zn/Ni and Sn-9Zn/Ni interfaces were observed after 1 h reflowing. When the couple was aged at 160°C for 1000 h, each IMC was converted to (Cu, Ni, Zn)6Sn5 and Cu5Zn8/(Cu, Ni, Sn)Zn/Ni5Zn21 phases at the Sn-1Zn/Ni and Sn-(5, 9)Zn/Ni interfaces. (Cu, Ni, Zn)6Sn5 and Cu5Zn8 were, respectively, formed at the Sn-1Zn/Cu and Sn-(5, 9)Zn/Cu interfaces for 1 h reflowing. After 100 h aging, the IMCs were converted to (Cu, Ni, Zn)6Sn5 and Cu5Zn8/(Cu, Zn)6Sn5 phases. This current study reveals that the IMC formation in Ni/(Sn- xZn)/Cu sandwich couples are very sensitive to the Zn concentration and thickness in Sn- xZn alloys.

  17. Peso, talla e IMC en relación con el cáncer de mama

    OpenAIRE

    Marín Oliván, Paula

    2015-01-01

    Introducción: la obesidad se ha relacionado con la aparición de diversos cánceres, incluyendo el de mama, siendo esta relación muy distinta en mujeres pre y postmenopáusicas y según el tipo de tumor y sus receptores. Además los cambios de peso, la altura y otras variables antropométricas también influyen. El objetivo principal de este estudio es analizar el grado de asociación que existe en la población de Cantabria entre el peso, talla e IMC y el desarrollo de cáncer de mama. Métodos: est...

  18. Peso, talla e IMC en relación con el cáncer de mama

    OpenAIRE

    Marín Oliván, Paula

    2015-01-01

    Introducción: la obesidad se ha relacionado con la aparición de diversos cánceres, incluyendo el de mama, siendo esta relación muy distinta en mujeres pre y postmenopáusicas y según el tipo de tumor y sus receptores. Además los cambios de peso, la altura y otras variables antropométricas también influyen. El objetivo principal de este estudio es analizar el grado de asociación que existe en la población de Cantabria entre el peso, talla e IMC y el desarrollo de cáncer de mama. Métodos: est...

  19. Enhanced IMC based PID controller design for non-minimum phase (NMP) integrating processes with time delays.

    Science.gov (United States)

    Ghousiya Begum, K; Seshagiri Rao, A; Radhakrishnan, T K

    2017-03-18

    Internal model control (IMC) with optimal H2 minimization framework is proposed in this paper for design of proportional-integral-derivative (PID) controllers. The controller design is addressed for integrating and double integrating time delay processes with right half plane (RHP) zeros. Blaschke product is used to derive the optimal controller. There is a single adjustable closed loop tuning parameter for controller design. Systematic guidelines are provided for selection of this tuning parameter based on maximum sensitivity. Simulation studies have been carried out on various integrating time delay processes to show the advantages of the proposed method. The proposed controller provides enhanced closed loop performances when compared to recently reported methods in the literature. Quantitative comparative analysis has been carried out using the performance indices, Integral Absolute Error (IAE) and Total Variation (TV).

  20. Relación entre autoconcepto físico, ansiedad e IMC en estudiantes universitarios mexicanos

    OpenAIRE

    Linares-Manrique, M.; Linares-Girela, D.; Schmidt-Rio-Valle, J.; Mato-Medina, O.; Fernández-García, R.; Cruz-Quintana, F.

    2016-01-01

    El propósito de la investigación es conocer y relacionar los resultados del autoconcepto físico, con diferentes tipos de ansiedad y el IMC en los estudiantes de enfermería y educación física dela península de Yucatán (México). La muestra estuvo formada por 264 participantes, de los cuales 91 eran varones y 173 mujeres, con edades comprendidas entre 18 y 25 años. Nuestros datos revelan que en el autoconcepto físico, los valores obtenidos por los estudiantes de educación físic...

  1. Relación entre autoconcepto físico, ansiedad e IMC en estudiantes universitarios mexicanos

    OpenAIRE

    Linares-Manrique, M.; Linares-Girela, D.; Schmidt-Rio-Valle, J.; Mato-Medina, O.; Fernández-García, R.; Cruz-Quintana, F.

    2016-01-01

    El propósito de la investigación es conocer y relacionar los resultados del autoconcepto físico, con diferentes tipos de ansiedad y el IMC en los estudiantes de enfermería y educación física dela península de Yucatán (México). La muestra estuvo formada por 264 participantes, de los cuales 91 eran varones y 173 mujeres, con edades comprendidas entre 18 y 25 años. Nuestros datos revelan que en el autoconcepto físico, los valores obtenidos por los estudiantes de educación físic...

  2. La对Sn-Ag-Cu无铅钎料与铜钎焊接头金属间化合物的影响%Effect of La on intermetallic compounds of Sn-Ag-Cu lead-free alloy soldered with copper

    Institute of Scientific and Technical Information of China (English)

    周迎春; 潘清林; 李文斌; 梁文杰; 何运斌; 李运春; 路聪阁

    2008-01-01

    研究微量稀土La在钎焊和时效过程中对Sn-3.0Ag-0.5Cu无铅钎料与铜基板的钎焊界面及钎料内部金属间化合物(IMC)的形成与生长行为的影响.结果表明:钎焊后钎焊界面形成连续的扇形Cu6Sn5化合物层,其厚度随La含量的增加而减小;在150℃时效100h后,连续的Cu3Sn化合物层在Cu6Sn5化合物层和铜基板之间析出,且Cu6Sn5层里嵌有Ag3Sn颗粒;界面金属间化合物总厚度随时效时间的延长而增厚,且在相同时效条件下随La含量的增加而减小;时效过程中金属间化合物生长动力学的时间系数(n)随着La含量的增加逐渐增大;钎焊后钎料内部Ag仍以共晶形式存在,时效后Ag3Sn颗粒沿钎料内部的共晶组织网络析出.

  3. Censorship of IMC Materials in Wisconsin Schools. Part I: Focus on Middle/Junior High Schools. Results of a Survey Conducted in May 1980.

    Science.gov (United States)

    Wisconsin State Dept. of Public Instruction, Madison.

    Professional staff in school libraries and instructional media centers (IMCs) located in 229 Wisconsin middle and junior high schools were surveyed anonymously to collect information on censorship attempts in their schools during 1978-79 and 1979-80. A total of 212 surveys were returned. Survey participants were asked to respond to questions…

  4. Imagen corporal, IMC, afrontamiento, depresión y riesgo de TCA en jóvenes universitarios

    Directory of Open Access Journals (Sweden)

    Lina-María Hernández-Cortés

    2013-10-01

    Full Text Available El presente estudio descriptivo correlacional pretendió determinar la relación entre estilo de afrontamiento, historia psiquiátrica familiar, salud percibida, IMC, género, percepción de la figura y depresión y el riesgo de padecer un trastorno de conducta alimentaria. Participaron 417 estudiantes universitarios que se seleccionaron de manera no aleatorizada estratificada con grupos de conveniencia. Para obtener los datos se utilizó la Ficha de Registro de Información General, la Escala Abreviada de las actitudes alimentarias EAT -26-M, el Cuestionario de Formas de Afrontamiento, el Inventario de Depresión de Beck, la Prueba de Optimismo Disposicional y el Registro de Percepción de la Figura. El análisis de datos se llevo a cabo mediante el uso de ecuaciones estructurales. Se concluyó que la interacción de las variables antecedentes psicológicos familiares, género, deseo de disminución del peso, satisfacción con la imagen corporal, estilo de afrontamiento evitativo y depresión en conjunto predicen el riesgo de padecer un TCA, se discuten los hallazgos y se evidencian las limitaciones del presente estudio.

  5. Integrated Marketing Communications(IMC) Theory and New Advertising Doctrine Revolution%整合营销传播理论与新广告主义革命

    Institute of Scientific and Technical Information of China (English)

    端木志坚; 洪永波

    2010-01-01

    整合营销传播(IMC)理论在广告业界的导入并未完成中国广告传播理念的根本性转移.中国广告尚期待一场深层意义上的实践性变革,即实现从集"销售主义"大成的"整合营销传播(IMC)"到"人文关怀与社会关怀"相融汇的新广告范式建构,亦即本文所论及的"新广告主义革命",以此完成广告传播的观念重建,最终实现从以物为本到以人为本的根本性变革.

  6. Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factor-kappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225.

    Science.gov (United States)

    Sclabas, Guido M; Fujioka, Shuichi; Schmidt, Christian; Fan, Zhen; Evans, Douglas B; Chiao, Paul J

    2003-01-01

    We have previously demonstrated that RelA is constitutively activated in the majority of human pancreatic cancers and plays an important role in tumorigenesis and metastasis. The antiapoptotic gene bcl-xl is a downstream target of RelA, and regulation of bcl-xl transcription is mediated directly by the nuclear factor kappaB (NF-kappaB) binding sites present in the upstream promoter element of the bcl-xl gene. In this study we investigated the effects of inhibition of epidermal growth factor receptor (EGFR) signaling pathway with the anti-EGFR monoclonal antibody IMC-C225 on constitutive NF-kappaB activation and regulation of apoptosis-related genes in human pancreatic cancer cells. We found that activation of EGFR can be blocked with the anti-EGFR antibody IMC-C225 in the human pancreatic cancer cell line MDA Panc-28, leading to a marked decrease in constitutive NF-kappaB DNA binding activity. Our data also suggest that downregulation of NF-kappaB DNA binding activity by IMC-C225 leads to a decrease in bcl-xl and bfl-1 expression. Therefore, targeting the NF-kappaB signaling pathway with an anti-EGFR antibody may be one strategy to restore apoptosis in human pancreatic cancer cells, thereby enhancing the effect of chemotherapy and radiation therapy.

  7. A new human natural killer leukemia cell line, IMC-1. A complex chromosomal rearrangement defined by spectral karyotyping: functional and cytogenetic characterization.

    Science.gov (United States)

    Chen, I-Ming; Whalen, Margaret; Bankhurst, Arthur; Sever, Cordelia E; Doshi, Rashmi; Hardekopf, David; Montgomery, Karen; Willman, Cheryl L

    2004-03-01

    A new human IL-2 dependent leukemic cell line with a natural killer (NK) cell phenotype, IMC-1, was established from an adult patient with aggressive NK cell leukemia. The IMC-1 cell line expresses the CD56, CD2, CD11a, CD38 and HLA-DR cell surface antigens, whereas the CD16 and CD8 antigens expressed on the primary leukemic blasts from which the cell line was derived were lost after 7 and 28 weeks of culture, respectively. The IMC-1 cell line displays functional NK cytotoxicity and lyses target cells in a non-MHC restricted, antibody-independent manner with equal or superior efficiency to freshly isolated NK cells. Cytogenetic analysis at presentation and after 55 weeks in culture revealed complex structural and numerical abnormalities, defined by classic G-banding and by spectral karyotyping (SKY). Three apparently intact copies of chromosome 8 occurred in the diagnostic bone marrow specimen; the cell line also contains three copies of chromosome 8 but each was structurally altered. The development and detailed characterization of this new NK leukemic cell line will facilitate biologic and functional studies of NK cells and chromosomal aberrations potentially important in leukemic transformation.

  8. Rationale for the development of IMC-3G3, a fully human immunoglobulin G subclass 1 monoclonal antibody targeting the platelet-derived growth factor receptor alpha.

    Science.gov (United States)

    Shah, Gaurav D; Loizos, Nick; Youssoufian, Hagop; Schwartz, Jonathan D; Rowinsky, Eric K

    2010-02-15

    A large body of evidence suggests that the platelet-derived growth factor (PDGF) family and associated receptors are potential targets in oncology therapeutic development because of their critical roles in the proliferation and survival of various cancers and in the regulation and growth of the tumor stroma and blood vessels. Several small molecules that nonspecifically target the PDGF signaling axis are in current use or development as anticancer therapies. However, for the majority of these agents, PDGF and its receptors are neither the primary targets nor the principal mediators of anticancer activity. IMC-3G3, a fully human monoclonal antibody of the immunoglobulin G subclass 1, specifically binds to the human PDGF receptor alpha (PDGFRalpha) with high affinity and blocks PDGF ligand binding and PDGFRalpha activation. The results of preclinical studies and the frequent expression of PDGFRalpha in many types of cancer and in cancer-associated stroma support a rationale for the clinical development of IMC-3G3. Currently, IMC-3G3 is being evaluated in early clinical development for patients with several types of solid malignancies.

  9. IMC-EB10, an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell lines and primary leukemic samples.

    Science.gov (United States)

    Piloto, Obdulio; Nguyen, Bao; Huso, David; Kim, Kyu-Tae; Li, Yiwen; Witte, Larry; Hicklin, Daniel J; Brown, Patrick; Small, Donald

    2006-05-01

    The class III receptor tyrosine kinase FLT3 is expressed on the blasts of >90% of patients with B-lineage acute lymphoblastic leukemias (ALL). In addition, it is expressed at extremely high levels in ALL patients with mixed lineage leukemia rearrangements or hyperdiploidy and is sometimes mutated in these same patients. In this report, we investigate the effects of treating ALL cell lines and primary samples with human anti-FLT3 monoclonal antibodies (mAb) capable of preventing binding of FLT3 ligand. In vitro studies, examining the ability of two anti-FLT3 mAbs (IMC-EB10 and IMC-NC7) to affect FLT3 activation and downstream signaling in ALL cell lines and primary blasts, yielded variable results. FLT3 phosphorylation was consistently inhibited by IMC-NC7 treatment, but in some cell lines, IMC-EB10 actually stimulated FLT3 activation, possibly as a result of antibody-mediated receptor dimerization. Through antibody-dependent, cell-mediated cytotoxicity, such an antibody could still prove efficacious against leukemia cells in vivo. In fact, IMC-EB10 treatment significantly prolonged survival and/or reduced engraftment of several ALL cell lines and primary ALL samples in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice. This occurred even when IMC-EB10 treatment resulted in FLT3 activation in vitro. Moreover, fluorescence-activated cell sorting and PCR analysis of IMC-EB10-treated NOD/SCID mice surviving 150 days post-leukemic cell injection revealed that FLT3 immunotherapy reduced leukemic engraftment below the level of detection in these assays (IMC-EB10 treatment did not select for resistant cells, because cells surviving IMC-EB10 treatment remain sensitive to IMC-EB10 cytotoxicity upon retransplantation. In vivo studies involving either partial depletion or activation of natural killer (NK) cells show that most of the cytotoxic effect of IMC-EB10 is mediated through NK cells. Therefore, such an antibody, either naked or conjugated to radioactive

  10. Static Analysis of IMC

    DEFF Research Database (Denmark)

    Skrypnyuk, Nataliya; Nielson, Flemming; Pilegaard, Henrik

    2012-01-01

    Process algebras formalism is highly suitable for producing succinct descriptions of reactive concurrent systems. Process algebras allow to represent them in a compositional way, as processes that run in parallel and interact, for example, through synchronisation or message passing. On the other...

  11. TRIO-012: a multicenter, multinational, randomized, double-blind phase III study of IMC-1121B plus docetaxel versus placebo plus docetaxel in previously untreated patients with HER2-negative, unresectable, locally recurrent or metastatic breast cancer.

    Science.gov (United States)

    Mackey, John; Gelmon, Karen; Martin, Miguel; McCarthy, Nicole; Pinter, Tamas; Rupin, Mathieu; Youssoufian, Hagop

    2009-11-01

    In this multinational, placebo-controlled, randomized phase III trial, Translational Research In Oncology (TRIO) will define the efficacy and safety of adding a novel antiangiogenic agent, IMC-1121B (ramucirumab), to standard first-line docetaxel chemotherapy for women with HER2-negative metastatic breast cancer. We will evaluate whether the addition of IMC-1121B prolongs progression-free survival and whether its use improves overall survival. Accrual is under way.

  12. Research advances in the interfacial IMC between the Sn-based solders and Cu substrate%锡基钎料与铜界面IMC的研究进展

    Institute of Scientific and Technical Information of China (English)

    位松; 尹立孟; 许章亮; 李欣霖; 李望云

    2012-01-01

    Research advances in the formation and growth mechanism of interfacial IMC between the Sn-based solder and Cu substrate in interconnection solder joint of electronic packaging are reviewed and commented. The formation and growth behavior of interfacial IMC in lead-free solder joints, the thermodynamics of IMC formation and the kinetics of IMC growth are expounded. Some other factors which are related to the growth behavior of interfacial IMC are also briefly proposed. In addition, the development trends of the research on interfacial IMC in lead-free electronic packaging are discussed.%对国内外电子封装“锡基钎料/铜基板”焊点体系界面IMC形成与生长机理的研究进展进行了回顾、评述,重点阐述了界面IMC的形成与生长行为、形成热力学和生长动力学,简要评述了相关因素对界面IMC生长行为的影响.最后,对无铅化电子封装互连焊点界面IMC研究的发展趋势进行了展望.

  13. Effect of contact metallization on electromigration reliability of Pb-free solder joints

    Science.gov (United States)

    Ding, Min; Wang, Guotao; Chao, Brook; Ho, Paul S.; Su, Peng; Uehling, Trent

    2006-05-01

    The effect of underbump metallization (UBM) on electromigration (EM) lifetime and failure mechanism has been investigated for Pb-free solder bumps of 97Sn3Ag composition in the temperature range of 110-155 °C. The EM lifetime of the SnAg Pb-free solders with either Cu or Ni UBM was found to be better than the eutectic SnPb (63Sn37Pb) solders but worse than high-Pb (95Pb5Sn) solders. In the test temperature range, the EM lifetimes were found to be comparable for Cu and Ni UBMs but with different activation energies: 0.64-0.72 eV for Cu UBM and 1.03-1.11 eV for Ni UBM. EM failure was observed only in solder bumps with electron current flow from UBM to the substrate. Failure analysis revealed that EM damage was initiated by the formation of intermetallic compounds (IMC) at the UBM/solder interface which was found to be significantly enhanced by mass transport driven by the electron current. Under EM, the continued growth of IMC with the dissolution of the UBM and the accumulation of Kirkendall voids resulted in the formation of interfacial cracks and eventual EM failure of the solder bump. For Ni UBM, the IMC formation was dominated by the Ni3Sn4 phase while for Cu UBM, a bilayer of Cu3Sn/Cu6Sn5 was found. Void formation at the Cu6Sn5/solder interface was found to be important in controlling the EM lifetime of the Cu UBM solder.

  14. Artrodese posterolateral vs artrodese circunferencial no tratamento da espondilolistese degenerativa: avaliação clínica e impacto do IMC nos resultados

    Directory of Open Access Journals (Sweden)

    Filipe Rodrigues Duarte

    2013-01-01

    Full Text Available OBJETIVO: O tratamento cirúrgico da espondilolistese degenerativa (ED apresenta vantagens quando comparado com o tratamento conservador. As técnicas cirúrgicas evoluíram no sentido de optimizar a fixação vertebral após descompressão, com o intuito de aumentar a taxa de artrodese. A fixação pedicular associada à fusão intersomática permite aumentar a área de contacto ósseo e assim a taxa de fusão, mas serão os resultados clínicos e funcionais superiores? MÉTODOS: Estudo retrospectivo incluindo 51 indivíduos (idade média de 61,2 anos submetidos a artrodese posterolateral (APL (19 e artrodese circunferencial (360º (32 de 1996 até 2009 com acompanhamento médio de 5,8 anos (2 a 14 anos. Incluídas apenas descompressões de um nível. Avaliação clínica (VAS - Visual Analogue Pain Score, satisfação global e avaliação funcional (Oswestry disability Index modificado. Cálculo do IMC (índice de massa corporal - avaliação clínica e funcional IMC ≥30 vs IMC <30. Estudo estatístico com SPSS®. RESULTADOS: Os resultados mostram franca melhoria clínica e funcional no tratamento cirúrgico da espondilolistese degenerativa, independentemente das técnicas estudadas. A taxa de satisfação é igualmente elevada. No confronto entre as duas técnicas de fixação não houve diferenças estatisticamente significativas. Relativamente ao IMC, os pacientes não obesos tiveram melhores resultados clínicos (p<0,05, não havendo diferenças relativas à função entre os dois grupos. CONCLUSÃO: A descompressão seguida de instrumentação vertebral é um tratamento eficaz para os pacientes com espondilolistese degenerativa. A técnica de artrodese utilizada não influencia os resultados clínicos e funcionais

  15. Estudio longitudinal del Índice de masa corporal (IMC) en pacientes en diálisis Longitudinal study on the body mass index (BMI) of dialysis patients

    OpenAIRE

    M. Palomares Bayo; J. J. Quesada Granados; A. Osuna Ortega; Asensio Peinado, C.; M.ª J. Oliveras López; H. López Gª de la Serrana; M.ª C. López Martínez

    2006-01-01

    La insuficiencia renal crónica está relacionada frecuentemente con la malnutrición, afectando aproximadamente a un tercio de los pacientes con enfermedad renal avanzada. Realizamos un estudio longitudinal de la evolución nutricional de 73 pacientes en programa de hemodiálisis periódica, valorando las modificaciones del parámetro antropométrico de índice de masa corporal (IMC) y su correspondencia con parámetros nutricionales bioquímicos como son proteínas totales (PT) y albúmina sérica (Alb)....

  16. Intermediate layer, microstructure and mechanical properties of aluminum alloy/stainless steel butt joint using laser-MIG hybrid welding-brazing method

    Science.gov (United States)

    Zhu, Zongtao; Wan, Zhandong; Li, Yuanxing; Xue, Junyu; Hui, Chen

    2017-07-01

    Butt joining of AA6061 aluminum (Al) alloy and 304 stainless steel of 2-mm thickness was conducted using laser-MIG hybrid welding-brazing method with ER4043 filler metal. To promote the mechanical properties of the welding-brazing joints, two kinds of intermediate layers (Al-Si-Mg alloy and Ag-based alloy) are used to adjust the microstructures of the joints. The brazing interface and the tensile strength of the joints were characterized. The results showed that the brazing interface between Al alloy and stainless steel consisted of double layers of Fe2Al5 (near stainless steel) and Fe4Al13 intermetallic compounds (IMCs) with a total thickness of 3.7 μm, when using Al-Si-Mg alloy as the intermediate layer. The brazing interface of the joints using Ag-based alloy as intermediate layer also consists of double IMC layers, but the first layer near stainless steel was FeAl2 and the total thickness of these two IMC layers decreased to 3.1 μm. The tensile strength of the joints using Al-Si-Mg alloy as the intermediate layer was promoted to 149 MPa, which was 63 MPa higher than that of the joints using Al-Si-Mg alloy as the intermediate layer. The fractures occurred in the brazing interface between Al alloy and stainless steel.

  17. Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector

    Directory of Open Access Journals (Sweden)

    Cronin Michael

    2008-06-01

    Full Text Available Abstract Background The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to identify and validate genes involved in the pathogenicity and environmental biology of the organism. The aim here was to develop a widely applicable method to tag L. monocytogenes strains, with a particular emphasis on the development of multiple strain competitive index assays. Results We have constructed a new site-specific integrative vector, pIMC, based on pPL2, for the selection of L. monocytogenes from complex samples. The pIMC vector was further modified through the incorporation of IPTG inducible markers (antibiotic and phenotypic to produce a suite of four vectors which allowed the discrimination of multiple strains from a single sample. We were able to perform murine infection studies with up to four EGDe isolates within a single mouse and showed that the tags did not impact upon growth rate or virulence. The system also allowed the identification of subtle differences in virulence between strains of L. monocytogenes commonly used in laboratory studies. Conclusion This study has developed a competitive index assay that can be broadly applied to all L. monocytogenes strains. Improved statistical robustness of the data was observed, resulting in fewer mice being required for virulence assays. The competitive index assays provide a powerful method to analyse the virulence or fitness of L. monocytogenes in complex biological samples.

  18. Purification, crystallization and preliminary X-ray diffraction analysis of inner membrane complex (IMC) subcompartment protein 1 (ISP1) from Toxoplasma gondii.

    Science.gov (United States)

    Tonkin, Michelle L; Brown, Shannon; Beck, Josh R; Bradley, Peter J; Boulanger, Martin J

    2012-07-01

    The protozoan parasites of the Apicomplexa phylum are devastating global pathogens. Their success is largely due to phylum-specific proteins found in specialized organelles and cellular structures. The inner membrane complex (IMC) is a unique apicomplexan structure that is essential for motility, invasion and replication. The IMC subcompartment proteins (ISP) have recently been identified in Toxoplasma gondii and shown to be critical for replication, although their specific mechanisms are unknown. Structural characterization of TgISP1 was pursued in order to identify the fold adopted by the ISPs and to generate detailed insight into how this family of proteins functions during replication. An N-terminally truncated form of TgISP1 was purified from Escherichia coli, crystallized and subjected to X-ray diffraction analysis. Two crystal forms of TgISP1 belonging to space groups P4(1)32 or P4(3)32 and P2(1)2(1)2(1) diffracted to 2.05 and 2.1 Å resolution, respectively.

  19. Accelerated Metastable Solid-liquid Interdiffusion Bonding with High Thermal Stability and Power Handling

    Science.gov (United States)

    Huang, Ting-Chia; Smet, Vanessa; Kawamoto, Satomi; Pulugurtha, Markondeya R.; Tummala, Rao R.

    2017-09-01

    Emerging high-performance systems are driving the need for advanced packaging solutions such as 3-D integrated circuits (ICs) and 2.5-D system integration with increasing performance and reliability requirements for off-chip interconnections. Solid-liquid interdiffusion (SLID) bonding resulting in all-intermetallic joints has been proposed to extend the applicability of solders, but faces fundamental and manufacturing challenges hindering its wide adoption. This paper introduces a Cu-Sn SLID interconnection technology, aiming at stabilization of the microstructure in the Cu6Sn5 metastable phase rather than the usual stable Cu3Sn phase. This enables formation of a void-free interface yielding higher mechanical strength than standard SLID bonding, as well as significantly reducing the transition time. The metastable SLID technology retains the benefits of standard SLID with superior I/O pitch scalability, thermal stability and current handling capability, while advancing assembly manufacturability. In the proposed concept, the interfacial reaction is controlled by introducing Ni(P) diffusion barrier layers, designed to effectively isolate the metastable Cu6Sn5 phase preventing any further transformation. Theoretical diffusion and kinetic models were applied to design the Ni-Cu-Sn interconnection stack to achieve the targeted joint composition. A daisy chain test vehicle was used to demonstrate this technology as a first proof of concept. Full transition to Cu6Sn5 was successfully achieved within a minute at 260°C as confirmed by scanning electron microscope (SEM) and x-ray energy dispersive spectroscopy (XEDS) analysis. The joint composition was stable through 10× reflow, with outstanding bond strength averaging 90 MPa. The metastable SLID interconnections also showed excellent electromigration performance, surviving 500 h of current stressing at 105 A/cm2 at 150°C.

  20. Microstructural Evolution of Lead-Free Solder Joints in Ultrasonic-Assisted Soldering

    Science.gov (United States)

    Ji, Hongjun; Wang, Qiang; Li, Mingyu

    2016-01-01

    Solder joint reliability greatly depends on the microstructure of the solder matrix and the morphology of intermetallic compounds (IMCs) in the joints. Addition of strengthening phases such as carbon nanotubes and ceramic particles to solder joints to improve their properties has been widely studied. In this work, ultrasonic vibration (USV) of casting ingots was applied to considerably improve their microstructure and properties, and the resulting influence on fluxless soldering of Cu/Sn-3.0Ag-0.5Cu/Cu joints and their microstructural evolution was investigated. It was demonstrated that USV application during reflow of Sn-based solder had favorable effects on β-Sn grain size refinement as well as the growth and distribution of various IMC phases within the joints. The β-Sn grain size was significantly refined as the ultrasound power was increased, with a reduction of almost 90% from more than 100 μm to below 10 μm. Long and large Cu6Sn5 tubes in the solder matrix of the joints were broken into tiny ones. Needle-shaped Ag3Sn was transformed into flake-shaped. These IMCs were mainly precipitated along β-Sn phase boundaries. High-temperature storage tests indicated that the growth rate of interfacial IMCs in joints formed with USV was slower than in conventional reflow joints. The mechanisms of grain refinement and IMC fragmentation are discussed and related to the ultrasonic effects.

  1. Effect of Joint Scale and Processing on the Fracture of Sn-3Ag-0.5Cu Solder Joints: Application to Micro-bumps in 3D Packages

    Science.gov (United States)

    Talebanpour, B.; Huang, Z.; Chen, Z.; Dutta, I.

    2016-01-01

    In 3-dimensional (3D) packages, a stack of dies is vertically connected to each other using through-silicon vias and very thin solder micro-bumps. The thinness of the micro-bumps results in joints with a very high volumetric proportion of intermetallic compounds (IMCs), rendering them much more brittle compared to conventional joints. Because of this, the reliability of micro-bumps, and the dependence thereof on the proportion of IMC in the joint, is of substantial concern. In this paper, the growth kinetics of IMCs in thin Sn-3Ag-0.5Cu joints attached to Cu substrates were analyzed, and empirical kinetic laws for the growth of Cu6Sn5 and Cu3Sn in thin joints were obtained. Modified compact mixed mode fracture mechanics samples, with adhesive solder joints between massive Cu substrates, having similar thickness and IMC content as actual micro-bumps, were produced. The effects of IMC proportion and strain rate on fracture toughness and mechanisms were investigated. It was found that the fracture toughness G C decreased with decreasing joint thickness ( h Joint). In addition, the fracture toughness decreased with increasing strain rate. Aging also promoted alternation of the crack path between the two joint-substrate interfaces, possibly proffering a mechanism to enhance fracture toughness.

  2. Associação entre IMC e teste de coordenação corporal para crianças (KTK. Uma meta-análise

    Directory of Open Access Journals (Sweden)

    Leonardo Gomes de Oliveira Luz

    2015-06-01

    Full Text Available O Teste de Coordenação Corporal para Crianças (Körperkoordinationstest für Kinder, KTK tem sido utilizado na avaliação da coordenação motora de crianças e adolescentes. O objetivo desta revisão sistemática com meta-análise foi analisar a relação entre o índice de massa corporal (IMC e o desempenho motor no KTK em crianças e jovens escolares saudáveis. O estudo baseou-se em pesquisas indexadas nas bases eletrônicas PubMed e SciELO. Os descritores foram: "Körperkoordinationstest für Kinder" e "KTK". Foram considerados artigos em inglês e português publicados até Outubro de 2014. A qualidade dos estudos foi determinada pelas Escalas PEDro e STROBE. Foi realizada meta-análise utilizando o software Comprehensive Meta-Analysis V2. Foram incluídos 10 estudos. O resultado global com base no modelo de efeitos fixos mostrou que valores maiores de IMC estão diretamente associados ao baixo desempenho no KTK. Apesar da pequena diferença entre ambos, a magnitude do efeito da associação foi classificada como pequena, porém, significativa para o sexo masculino (r=0,29; IC95% 0,27 a 0,32; Z=22,47; p=0,000 e moderada para o sexo feminino (r=0,32; IC95% 0,30 a 0,34; Z=24,76; p=0,000. Os estudos apresentaram características amostrais bastante divergentes quanto ao tamanho da amostra e a faixa etária dos sujeitos, além de nenhum deles ter analisado o estado maturacional dos participantes. Conclui-se que há uma tendência de relação positiva entre valores elevados de IMC e o baixo desempenho no KTK. Para confirmação desta tendência, recomenda-se que os próximos trabalhos considerem o estado maturacional dos participantes, além de possibilitarem uma análise por sexo e idade.

  3. IMC-1新型缓蚀剂的复配测试结果及评价%A New Inhibitor IMC 1— — Its Study and Evaluation

    Institute of Scientific and Technical Information of China (English)

    王大喜; 刘丽霞

    2001-01-01

    介绍了IMC-1新型咪唑啉缓蚀剂的复配测试结果及评价,用电化学法和失重法测试了在不同浓度、不同温度和不同腐蚀介质下的缓蚀效果.结果表明,IMC-1缓蚀剂在较低的浓度下缓蚀率可达94.6%左右,适用于酸性腐蚀介质.

  4. CORRELAÇÃO ENTRE O ÍNDICE DE MASSA CORPÓREA (IMC), GRAVIDADE E CONTROLE DA ASMA EM PACIENTES PARTICIPANTES DE UM PROGRAMA ESTRUTURADO DE EDUCAÇÃO EM ASMA

    OpenAIRE

    Passos, Lucas Santana; Universidade Federal do Maranhão - UFMA; Costa, Maria do Rosário da Silva Ramos; Universidade Federal do Maranhão - UFMA

    2012-01-01

    O aumento do índice de massa corporal (IMC) tem sido associado a uma maior prevalência da asma em adultos. O presente estudo tem o objetivo de correlacionar o IMC com a gravidade e o nível de controle da asma dos pacientes atendidos em um programa estruturado de educação em asma. 182 pacientes diagnosticados como portadores de asma brônquica foram entrevistados e classificou-se a gravidade da asma através da história clínica, dos resultados da espirometria e da medicação prescrita, segundo a ...

  5. Correlação entre o índice de massa corporal (IMC de gestantes e hipotensão após raquianestesia para cesarianas

    Directory of Open Access Journals (Sweden)

    Fernando Souza Nani

    2011-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Existem poucas publicações correlacionando hipotensão em gestantes obesas, principalmente em obesas mórbidas, após raquianestesia para cesárea. Objetivamos avaliar a incidência de hipotensão correlacionada ao IMC. MÉTODO: No grupo Eutrofia foram incluídas 49 pacientes com IMC pré-gestacional abaixo de 25 kg.m-2 e no grupo Sobrepeso, 51 pacientes com IMC igual ou acima de 25 kg.m-2. Após raquianestesia, foram anotadas as medidas de pressão arterial, volume de cristaloides infundidos e dose de vasopressores utilizada até o nascimento. Redução da pressão arterial sistólica abaixo de 100 mmHg ou 10% da pressão arterial sistólica (PAS inicial foi classificada como hipotensão e corrigida com vasopressor. RESULTADOS: Os episódios de hipotensão foram menores no grupo Eutrofia (5,89 ± 0,53 vs. 7,80 ± 0,66; p = 0,027, assim como a quantidade de cristaloides (1.298 ± 413,6 mL vs. 1.539 ± 460,0 mL; p = 0,007 e o uso de vasopressores (5,87 ± 3,45 bolus vs. 7,70 ± 4,46 bolus; p = 0,023. Quanto às doenças associadas, observamos maior incidência de diabetes entre as gestantes obesas (29,41% vs. 9,76%, RR 1,60; IC 95%: 1,15-2,22; p = 0,036, porém não houve diferença entre os grupos em relação à incidência de doença hipertensiva específica da gestação (DHEG (sobrepeso: 21,57%, peso normal: 12,20%, RR 1,30; IC 95%: 0,88-1,94; p = 0,28. CONCLUSÕES: Na amostra estudada, IMC pré-gestacional maior ou igual a 25 kg.m-2 apresentou-se como fator de risco para hipotensão após raquianestesia em pacientes submetidas a cesáreas. O mesmo grupo de pacientes necessitou de um número de doses maior de vasopressores. A valorização desses achados implica aprimorar as técnicas anestésicas nessas pacientes a fim de diminuir as consequências da hipotensão pós-raquianestesia, tanto na gestante como no feto.

  6. Innovation of Mountain Agricultural Industrialization Based on IMC%基于IMC的山区农业产业化经营创新探讨

    Institute of Scientific and Technical Information of China (English)

    王烨冰

    2011-01-01

    农业产业化是深化农村改革、发展农村经济的必然选择.在山区农业产业化经营管理中运用IMC(整合营销传播)管理理念,对于促进山区农业和农村经济结构战略调整而言,是一次产业化经营体制的创新.文章介绍了IMC的概念及其主要特征,分析了山区农业产业化经营创新的必要性以及如何运用IMC管理理念构建山区农业产业化经营创新平台,为发展山区农业经济服务.

  7. Hábitos alimentares: Sua influência no índice de massa corporal (IMC) em portadores de Síndrome de Down

    OpenAIRE

    Neves, Lilian Ferreira; Durães, Grayce Laiz Lima Silveira; Bezerra, Kátia Francielly; Capuchinho, Laura Caroline Ferreira Mendes; Lopes, Wanessa Casteluber

    2015-01-01

    A Síndrome de Down (SD) consiste em um determinismo gené­tico, definido pelo excesso do cromossomo de número 21, o que determina suas características específicas como o fenótipo, a hipotonia e o comprome­timento intelectual. Neste estudo objetivou-se avaliar os hábitos sobre ali­mentação e nutrição, e o índice de massa corporal (IMC) em 105 alunos com SD matriculados na Fundação Educacional Clarice Albuquerque de Montes Claros, Minas Gerais. Para tanto, realizou-se uma pesquisa quali-quantita...

  8. 基于IMC-PID的釜式反应器控制系统综合教学实验的设计%Design of an integrated teaching experiment by using the control system with continuous stirred tank reactor(CSTR)based on IMC-PID

    Institute of Scientific and Technical Information of China (English)

    李大字; 刘霞; 张永德; 孙洪程; 刘展

    2008-01-01

    基于系统仿真平台MPCE一1000设计了聚丙烯连续聚合反应CSTR的IMC-PID控制仿真实验系统.在该实验中,首先按照实际工艺流程对实验设备进行相应的连接,接着进行控制方案设计与组态,然后运行控制方案并且进行调试,最后叙述实验步骤,并且对控制方案进行比较与评价.该实验通过简单直观的方法,让学生们了解和掌握如何对一个工业实际系统进行系统辨识,以及通过辨识出的数学模型设计IMC-PID控制器,以便取得更好的控制效果.

  9. Bi对Sn-0.3Ag-0.7Cu-xBi/Ni焊点IMC的影响%Influence of Bi on IMC of Sn-0.3Ag-0.7Cu-xBi/Ni Solder

    Institute of Scientific and Technical Information of China (English)

    权延慧; 李锋

    2011-01-01

    无铅钎料和基板间金属间化合物(1MC)的生长对元器件的可靠性有重要影响.使用Sn-0.3Ag-0.7Cu-xBi无铅钎料与Ni盘进行焊接,并对焊点进行了180℃时效试验,时效时间分别为O、24、96、216和384h.采用金相显微镜、扫描电镜和能谱仪观察分析了钎料与Ni界面IMC的生长及形貌变化,并对其焊点IMC层Ni的分布进行了分析,同时对其界面生长速率进行了拟合.结果表明:Sn-0.3Ag-0.7Cu焊料与Ni焊盘之间的IMC是棒状的(CuxNi1-x)6Sn5,Bi的加入并没有起到很好的抑制作用,而是随着Bi含量的增加IMC先增加后减少.Sn-O.3Ag-0.7Cu/Ni焊点IMC中Ni的平均含量(wN)分为15%、5%两区域.由近Ni向钎料基体方向呈下降趋势.但是Sn-O.3Ag-0.7Cu-3.0Bi/Ni焊点IMC中Ni的平均含量在7%左右.时效后IMC层的厚度会随着老化时间的延长而增加,但是Sn-0.3Ag-0.7Cu-xBi/Ni焊点由于Bi的析出IMC增长得缓慢;Sn-0.3Ag-0.7Cu/Ni焊点(CuxNi1-x)6Sn5中15%Ni的含量区域逐渐过渡到5%区域,但是Sn-0.3Ag-0.7Cu-xBi/Ni焊点IMC中Ni的平均含量维持9%较时效前有所增加.通过生长速率计算,Sn-O.3Ag-0.7Cu-xBi/Ni焊点IMC的生长速率随着Bi含量的增加而减少.%The growth of intermetallic compounds (IMC) between lead-free solder and pad has an important influence on the reliability of primary device. Ni substrate was welded by Sn-0.3Ag-0.7Cu-xBi lead-free solder, and the joints were aging-treated at 180C, aging time was 0, 24, 95, 216 and 384 h respectively, The growth and morphology characteristics of the IMCs were investigated by metallographic microscope, SEM and EDX. The content change of Ni in the IMC was also analysed, meanwhile, the IMC growth rates were fitted by experimental data. The results show that the IMC between Sn-0.3Ag-0.7Cu-xBi and Ni substrate is (CuxNi1-x)6Sn5- The effect of controlling the thickness of IMC is not very good after the addition of Bi, with the increase of Bi content, the thickness of IMC

  10. Synthetic Vision Systems in GA Cockpit-Evaluation of Basic Maneuvers Performed by Low Time GA Pilots During Transition from VMC to IMC

    Science.gov (United States)

    Takallu, M. A.; Wong, D. T.; Uenking, M. D.

    2002-01-01

    An experimental investigation was conducted to study the effectiveness of modern flight displays in general aviation cockpits for mitigating Low Visibility Loss of Control and the Controlled Flight Into Terrain accidents. A total of 18 General Aviation (GA) pilots with private pilot, single engine land rating, with no additional instrument training beyond private pilot license requirements, were recruited to evaluate three different display concepts in a fixed-based flight simulator at the NASA Langley Research Center's General Aviation Work Station. Evaluation pilots were asked to continue flight from Visual Meteorological Conditions (VMC) into Instrument Meteorological Conditions (IMC) while performing a series of 4 basic precision maneuvers. During the experiment, relevant pilot/vehicle performance variables, pilot control inputs and physiological data were recorded. Human factors questionnaires and interviews were administered after each scenario. Qualitative and quantitative data have been analyzed and the results are presented here. Pilot performance deviations from the established target values (errors) were computed and compared with the FAA Practical Test Standards. Results of the quantitative data indicate that evaluation pilots committed substantially fewer errors when using the Synthetic Vision Systems (SVS) displays than when they were using conventional instruments. Results of the qualitative data indicate that evaluation pilots perceived themselves to have a much higher level of situation awareness while using the SVS display concept.

  11. Blockade of insulin-like growth factor type-1 receptor with cixutumumab (IMC-A12): a novel approach to treatment for multiple cancers.

    Science.gov (United States)

    Rowinsky, Eric K; Schwartz, Jonathan D; Zojwalla, Naseem; Youssoufian, Hagop; Fox, Floyd; Pultar, Philippe; Novosyadlyy, Ruslan; Cosaert, Jan; Ludwig, Dale L

    2011-12-01

    Insulin-like growth factor type-1 receptor (IGF-1R) plays a central role in cell proliferation and survival and is overexpressed in many tumor types. Notably, IGF-1R-mediated signaling confers resistance to diverse cytotoxic, hormonal, and biologic agents, suggesting that therapies targeting IGF-1R may be effective against a broad range of human malignancies. Cixutumumab (IMC-A12; ImClone Systems) is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically inhibits IGF-1R signaling. Binding of cixutumumab to IGF-1R results in receptor internalization and degradation. Because cixutumumab is an IgG1 monoclonal antibody, it may induce additional cytotoxicity via immune effector mechanisms such as antibody-dependent cellular cytotoxicity. In preclinical studies, cixutumumab monotherapy resulted in growth inhibition of multiple experimental cancers. Moreover, cixutumumab safely enhanced the tumor growth inhibitory and cytotoxic effects of a broad range of chemotherapeutics, and modulated the action of agents that target hormone receptors and signal transduction, which may have implications for cancer therapy. Herein, we review published preclinical and clinical data for cixutumumab and provide a comprehensive overview of selected clinical studies.

  12. CORRELAÇÃO ENTRE O IMC E AS CAPACIDADES MOTORAS CONDICIONAIS EM JOVENS PRATICANTES DE MODALIDADES DESPORTIVAS EXTRA-CURRICULARES

    Directory of Open Access Journals (Sweden)

    C. Alves

    2015-04-01

    Full Text Available As capacidades motoras são “a base para a capacidade de aprendizagem sensorial e motora”, responsáveis pela execução de uma ação, desde a mais simples à mais complexa (andar, correr, etc. (Moraes, 2003. Estas capacidades são condicionadas por fatores genéticos, contudo, desenvolvem-se através do treino, potenciando um elevado desempenho motor (Moraes, 2003. É, por isso, importante avaliar as capacidades motoras dos jovens, adequando por esta via, as experiências motoras a cada criança/grupo de crianças e/ou jovens (Neto, Marcarenhas, Nunes, Lepre & Campos, 2004. As relações entre a prática de atividade física e obesidade configuram-se como objeto de estudo prioritário e as evidências na literatura apontam para a existência de associação entre o excesso de peso na adolescência e alterações da sua saúde na idade adulta, dado o excesso de gordura corporal, além de ser fator de risco para diversas doenças, prejudica o desempenho físico. Objetivo: Analisar a associação entre o IMC e as Capacidades Motoras Condicionais em jovens praticantes de modalidades desportivas extra-curriculares.

  13. Electromigration-induced cracks in Cu/Sn3.5Ag/Cu solder reaction couple at room temperature

    Institute of Scientific and Technical Information of China (English)

    He Hongwen; Xu Guangchen; Guo Fu

    2009-01-01

    Electromigration (EM) behavior of Cu/Sn3.5Ag/Cu solder reaction couple was investigated with a high current density of 5× 103 A/cm2 at room temperature. One dimensional structure, copper wire/solder ball/copper wire SRC was designed and fabricated to dissipate the Joule heating induced by the current flow. In addition, thermomigration effect was excluded due to the symmetrical structure of the SRC. The experimental results in-dicated that micro-cracks initially appeared near the cathode interface between solder matrix and copper substrate after 474 h current stressing. With current stressing time increased, the cracks propagated and extended along the cathode interface. It should be noted that the continuous Cu6Sn5 intcrmetallic compounds (LMCs) layer both at the anode and at the cathode remained their sizes. Interestingly, tiny cracks appeared at the root of some long column-type Cu6Sn5 at the cathode interface due to the thermal stress.

  14. Relação entre atividade física e desportiva, níveis de IMC, perceções de sucesso e rendimento escolar

    Directory of Open Access Journals (Sweden)

    Fernando Bastos

    2015-12-01

    Full Text Available O excesso de peso é cada vez maior entre da população escolar jovem. Uma vez que não é evidente qual a atitude dos alunos com sobrepeso e obesidade face à participação em atividades físicas e sua relação com o desempenho escolar pretendemos identificar os factores de influência no contexto da EF escolar. Participaram neste estudo 490 alunos dos 3º ciclo e ensino secundário, divididos por sexo. Os valores de IMC foram ajustados para sexo e idade e criados três grupos: Magreza; peso normal; e excesso de peso. Os valores dos resultados escolares foram normalizadas para uma escala de 1 a 5 valores. A participação em atividades desportivas, regularidade de prática e percepção do sucesso escolar foi medida por questionário. Após análise exploratória dos dados foram realizados os testes do Qui-quadrado, ANOVA e correlação de Pearson. O eta quadrado parcial (η² foi reportado como medida da magnitude do efeito das diferenças verificadas nas ANOVAs. Foi considerado o valor de α de 0.05. Os resultados mostraram que alunos com excesso de peso e magreza reportaram menores níveis de atividade física em relação a alunos normoponderais (4.20±1.73, 4.06±1.77, 4.61±1.73; p=0.044; η²=0.01, resp.. A maior parte dos alunos definiu o seu sucesso escolar através da aprovação/transição de ano a par de boas classificações, tendo este grupo obtido níveis superiores de prática (4.57±1.71, p=0.03 Verificaram-se efeitos significativos da variável níveis de IMC nas classificações médias finais e na disciplina de EF, em que os alunos normoponderais obtiveram melhores classificações do que os alunos com excesso de peso. Além disso, verificaram-se correlações significativas entre as classificações de Português e Matemática (r=0.80; p<0.001, entre as classificações de EF e Português (r=0.36; p<0.001, e entre as classificações de EF e Matemática (r=0.42; p<0.001. Os alunos com sobrepeso apresentaram n

  15. Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2.

    Science.gov (United States)

    Spratlin, Jennifer L; Cohen, Roger B; Eadens, Matthew; Gore, Lia; Camidge, D Ross; Diab, Sami; Leong, Stephen; O'Bryant, Cindy; Chow, Laura Q M; Serkova, Natalie J; Meropol, Neal J; Lewis, Nancy L; Chiorean, E Gabriela; Fox, Floyd; Youssoufian, Hagop; Rowinsky, Eric K; Eckhardt, S Gail

    2010-02-10

    PURPOSE To evaluate the safety, maximum-tolerated dose (MTD), pharmacokinetics (PKs), pharmacodynamics, and preliminary anticancer activity of ramucirumab (IMC-1121B), a fully human immunoglobulin G(1) monoclonal antibody targeting the vascular endothelial growth factor receptor (VEGFR)-2. PATIENTS AND METHODS Patients with advanced solid malignancies were treated once weekly with escalating doses of ramucirumab. Blood was sampled for PK studies throughout treatment. The effects of ramucirumab on circulating vascular endothelial growth factor-A (VEGF-A), soluble VEGFR-1 and VEGFR-2, tumor perfusion, and vascularity using dynamic contrast-enhanced magnetic resonance imaging were assessed. Results Thirty-seven patients were treated with 2 to 16 mg/kg of ramucirumab. After one patient each developed dose-limiting hypertension and deep venous thrombosis at 16 mg/kg, the next lower dose (13 mg/kg) was considered the MTD. Nausea, vomiting, headache, fatigue, and proteinuria were also noted. Four (15%) of 27 patients with measurable disease had a partial response (PR), and 11 (30%) of 37 patients had either a PR or stable disease lasting at least 6 months. PKs were characterized by dose-dependent elimination and nonlinear exposure consistent with saturable clearance. Mean trough concentrations exceeded biologically relevant target levels throughout treatment at all dose levels. Serum VEGF-A increased 1.5 to 3.5 times above pretreatment values and remained in this range throughout treatment at all dose levels. Tumor perfusion and vascularity decreased in 69% of evaluable patients. CONCLUSION Objective antitumor activity and antiangiogenic effects were observed over a wide range of dose levels, suggesting that ramucirumab may have a favorable therapeutic index in treating malignancies amenable to VEGFR-2 inhibition.

  16. Correlação entre Índice de massa Corporal (IMC pré-natal e peso ao nascer – um estudo longitudinal - doi: 10.5020/18061230.2012.p356

    Directory of Open Access Journals (Sweden)

    Saurabh Rambiharilal Shrivastava

    2012-11-01

    Full Text Available Objetivos: Estudar a correlação entre Índice de Massa Corporal (IMC no período pré-natal e o peso de nascimento da criança, bem como, os determinantes sócio-demográficos de peso ao nascer. Métodos: Um estudo longitudinal de um ano de duração, de junho 2010 a maio de 2011, foi realizado em uma favela urbana de Mumbai, Índia. O método de amostragem universal foi aplicado, incluindo como sujeitos todas as mulheres grávidas que realizaram pré-natal com, no mínimo, duas visitas, incluindo pelo menos uma no terceiro trimestre, registradas no centro urbano de saúde, de junho a agosto de 2010. Mulheres com qualquer estado mórbido pré-existente ou com histórico de gestações com nascimento de gêmeos ou de criança com qualquer má-formação congênita, ou inda, com ocorrência de natimorto ou parto em casa, foram excluídas do estudo. Estas mulheres foram acompanhadas durante os próximos meses até o parto. O peso materno foi medido em cada visita e calculado o IMC, ou o IMC médio, no caso de mais de uma visita em qualquer trimestre. O peso ao nascer foi registrado a partir de dados do hospital ou maternidade. Resultados: A prevalência de Baixo Peso ao Nascer (BPN foi de 26,7%. Correlação entre o IMCmaterno do terceiro trimestre e o peso ao nascer foi moderadamente positiva. 60,8% da variabilidade no peso ao nascer podem ser preditos pelo IMC materno no terceiro trimestre. Conclusão: O IMC materno no terceiro trimestre pode ser usado como um preditor de peso ao nascimento neonatal. Informação, Educação e Aconselhamento (IEC sobre a utilização do pré-natal podem ajudar na redução da incidência de Baixo Peso ao Nascer (BPN.

  17. Nonmixing layers

    Science.gov (United States)

    Gaillard, Pierre; Giovangigli, Vincent; Matuszewski, Lionel

    2016-12-01

    We investigate the impact of nonideal diffusion on the structure of supercritical cryogenic binary mixing layers. This situation is typical of liquid fuel injection in high-pressure rocket engines. Nonideal diffusion has a dramatic impact in the neighborhood of chemical thermodynamic stability limits where the components become quasi-immiscible and ultimately form a nonmixing layer. Numerical simulations are performed for mixing layers of H2 and N2 at a pressure of 100 atm and temperature around 120-150 K near chemical thermodynamic stability limits.

  18. The influence of BMI and psychological variables in the body size estimation among adult women = A influência do IMC e variáveis psicológicas na estimação da imagem corporal em mulheres adultas = La influencia de IMC y variables psicológicas en la estimación del tamaño corporal entre las mujeres adultas

    Directory of Open Access Journals (Sweden)

    Xavier, Gabriela Salim

    2016-01-01

    Full Text Available O objetivo desse estudo foi quantificar a estimação da imagem corporal para avaliar as variáveis que a influenciam – Índice de Massa Corporal (IMC, insatisfação com a imagem corporal e sintomas depressivos em mulheres eutróficas (n=40 e com excesso de peso (n=40. A avaliação da imagem corporal e dos sintomas depressivos foi conduzida por meio da Escala de Figuras de Silhuetas (EFS e pelo Inventário de Depressão de Beck (BDI, em suas versões brasileiras, respectivamente. No grupo eutrófico, a insatisfação e a pontuação do BDI explicaram 55% e 12% da variação da estimação, respectivamente. No grupo com excesso de peso, a insatisfação com a imagem corporal foi responsável por 14% da variação da estimação da imagem corporal, enquanto o IMC, individualmente, por somente 9%. Quando avaliados em conjunto, esse percentual aumenta para 42%, indicando que juntos – IMC e insatisfação – agregam maior valor explicativo para essa variável. A insatisfação foi considerada a variável mais saliente, influenciando em maiores proporções os valores de estimação obtidos, particularmente entre as mulheres eutróficas

  19. Seguimento de 9 anos da bioprótese valvular cardíaca de pericárdio bovino IMC-Biomédica: estudo multicêntrico Nine year follow-up of the bovine pericardial prosthetic valve IMC-Biomedica: a multicenter study

    Directory of Open Access Journals (Sweden)

    Alexandre V Brick

    1987-12-01

    Full Text Available De dezembro de 1977 a novembro de 1986, foi usado o bioenxerto valvular cardíaco de pericárdio bovino IMC-Biomédica na posição mitral, em 798 pacientes, com idade média de 42 anos. Os 722 pacientes sobreviventes foram observados por um período de até 9 anos, representando 27036 meses, ou 2253 anos. O estudo indicou um índice de sobrevida de 66% para os adultos e 69% para os jovens, sendo de 94% e 80% o índice de sobrevida para os adultos e jovens, respectivamente, com pós-operatório de 5 anos. A freqüência das complicações diante da amostra analisada foi: 0,4% de rotura do tecido; 0,4% de vazamento paravalvular; 2,7% de acidente vascular cerebral; 3,2% de endocardite infecciosa; 4,4% de calcificação. A curva atuarial de calcificação entre os anos de 1978 e 1982 (Grupo I mostrou 94% dos adultos e 12% dos jovens livres dessa complicação. Por outro lado, de 1982 a 1986 (Grupo II, esse índice subiu para 99,0% entre os adultos e 92,0% para os jovens. Deste modo, concluímos que a nossa opção pela bioprótese de pericárdio bovino foi apropriada, visto que 96% dos pacientes estiveram livres de complicações fatais relacionadas à bioprótese, o que significa que, em 9 anos, o potencial da bioprótese foi apenas de 4%.A mitral pericardial bioprosthetic valve IMC-Biomedica was implanted in a consecutive series of 798 patients with mean age of 52 years, from December 1977 to November 1978. The 722 patients who survived operation were observed during a period of 9 years (mean 27036 months or 2253 years. Actuarial studies indicated an expected survived rate at 9 years of 66% for adult patients and 68% for younger patients. The probability of complications were the following: rupture 0.4; perivalvar leak 0.4%; thromboembolysm 2.7%; endocarditis 3.2%; calcification 4.4%. The actuarial freedom from calcification between 1977 to 1982 (Group I was 94.0% to adults and 12.0% to younger patients. On the other hand, between 1982 to 1986

  20. Vascular endothelial growth factor receptor-1 in human cancer: concise review and rationale for development of IMC-18F1 (Human antibody targeting vascular endothelial growth factor receptor-1).

    Science.gov (United States)

    Schwartz, Jonathan D; Rowinsky, Eric K; Youssoufian, Hagop; Pytowski, Bronislaw; Wu, Yan

    2010-02-15

    The human vascular endothelial growth factor receptor-1 (VEGFR-1, or Flt-1) is widely expressed in normal and pathologic tissue and contributes to the pathogenesis of both neoplastic and inflammatory diseases. In human cancer, VEGFR-1 mediated signaling is responsible for both direct tumor activation and angiogenesis. VEGFR-1 mediated activation of nonmalignant supporting cells, particularly stromal, dendritic, hematopoietic cells, and macrophages, is also likely important for cancer pathogenesis. VEGFR-1 is also hypothesized to enable the development of cancer metastases by means of activation and premetastatic localization in distant organs of bone marrow-derived hematopoietic progenitor cells, which express VEGFR-1. IMC-18F1 is a fully human IgG(1) antibody that binds to VEGFR-1 and has been associated with the inhibition of cancer growth in multiple in vitro and human tumor xenograft models. The preliminary results of phase 1 investigations have also indicated a favorable safety profile for IMC-18F1 at doses that confer antibody concentrations that are associated with relevant antitumor activity in preclinical models.

  1. Identification and cloning of a novel isoform of mouse secretory leukocyte protease inhibitor, mSLPI-beta, overexpressed in murine leukemias and a highly liver metastatic tumor, IMC-HA1 cells.

    Science.gov (United States)

    Morita, M; Arakawa, H; Nishimura, S

    1999-01-01

    Several genes showing transcriptional alteration in a highly liver metastatic murine carcinoma cell line, IMC-HA1, were identified by mRNA differential display system. Among them, a gene identical to mSLPI was isolated as mSLPI-alpha and -beta. They were produced through an alternative splicing. Their full-length cDNA sequences were determined, and their expression in various murine tumors and normal tissues was analysed. The deduced translation product of mSLPI-alpha showed 59% identity to hSLPI. Although mSLPI-beta had the same 103-amino-acid sequence from the carboxyl terminus, the amino terminus showed hydrophilicity opposite mSLPI-alpha or hSLPI. The mSLPI-alpha was expressed ubiquitously in various tumor cell lines. Interestingly, however, mSLPI-beta expression was only observed in P388 and L1210 leukemias and IMC-HA1 cells, and in lower amounts in three normal tissues (thymus, lung and spleen), suggesting that mSLPI, and in particular the unusual splicing product, mSLPI-beta, plays a specific role in these cells, including malignant processes of tumor cells.

  2. Control Logic for the Interlock system of the ATLAS Insertable B-Layer

    CERN Document Server

    Riegel, Christian

    Part of the first upgrade program of the ATLAS detector is the installation of the Insertable B-Layer (IBL) as a fourth and innermost detector layer of the ATLAS pixel detector to prepare the tracking system for the expected increase of pile-up events. As with every sub-detector, the IBL and its components have to be monitored and controlled via a Detector Control System (DCS). A hardware-based interlock system is installed on-site to prevent detector and people working at the detector from serious harm and damage. For the IBL, the logical processing of interlock signals is realised in Interlock Matrix Crates (IMCs) using Complex Programmable Logic Devices (CPLD). One part of this master thesis is the automatic implementation of the logical assignments from database information. A script was developed to generate the needed file to program the CPLD. The second part of this thesis is the design of a test setup to verify the functionality of the electrical components of each IMC and to confirm the correct proce...

  3. Maternal BMI and migration status as predictors of childhood obesity in Mexico IMC materno y migración como predictor de obesidad infantil de México

    Directory of Open Access Journals (Sweden)

    A. Jiménez-Cruz

    2011-02-01

    Full Text Available Objective: To assess the association of maternal migration to Baja California, body mass index (BMI status, children's perceived food insecurity, and childhood lifestyle behaviors with overweight (BMI > 85% ile, obesity (BMI > 95% ile and abdominal obesity (Waist Circumference > 90% ile. Methods: Convenience sampling methods were used to recruit a cross-sectional sample of 4th, 5th and 6th grade children and their parents at Tijuana and Tecate Public Schools. Children's and parents' weights and heights were measured. Children were considered to have migrant parents if parents were not born in Baja California. Results: One hundred and twenty-two children and their parents were recruited. The mean age of the children was 10.1 ± 1.0 years. Forty nine per cent of children were overweight or obese. Children with obese parents (BMI > 30 had greater odds of being obese, Odds Ratio (OR 4.9 (95% Confidence Interval (CI, 1.2-19, p = 0.03. Children with migrant parents had greater odds of being obese, OR= 3.7 (95% CI, 1.6-8.3, p = 0.01 and of having abdominal obesity, OR = 3.2 (95% CI, 1.4-7.1, p = 0.01. Children from migrant parents have greater risk of higher consumption of potato chips, OR = 8.0 (95% CI, 2.1 -29.1, p = 0.01. Children from non-migrant parents had greater odds of being at risk of hunger. Conclusions: Parental obesity and migration are associated with increased risk of obesity among Mexican children. Children whose parents were born in Baja California have greater odds of being at risk of hunger. Further studies should evaluate the role of migration on risk for childhood obesity.Objetivo: Determinar la asociación entre la inmigración materna a Baja California, el índice de masa corporal (IMC, la percepción de inseguridad alimentaria de los niños, y los estilos de vida y el sobrepeso, (BMI > 85% ila, la obesidad (BMI > 95% ila y la obesidad abdominal (Circunferencia de Cintura > 90% ila. Métodos: Se realizó una muestra por

  4. Electromigration Reliability and Morphologies of Cu Pillar Flip-Chip Solder Joints with Cu Substrate Pad Metallization

    Science.gov (United States)

    Lai, Yi-Shao; Chiu, Ying-Ta; Chen, Jiunn

    2008-10-01

    The Cu pillar is a thick underbump metallurgy (UBM) structure developed to alleviate current crowding in a flip-chip solder joint under operating conditions. We present in this work an examination of the electromigration reliability and morphologies of Cu pillar flip-chip solder joints formed by joining Ti/Cu/Ni UBM with largely elongated ˜62 μm Cu onto Cu substrate pad metallization using the Sn-3Ag-0.5Cu solder alloy. Three test conditions that controlled average current densities in solder joints and ambient temperatures were considered: 10 kA/cm2 at 150°C, 10 kA/cm2 at 160°C, and 15 kA/cm2 at 125°C. Electromigration reliability of this particular solder joint turns out to be greatly enhanced compared to a conventional solder joint with a thin-film-stack UBM. Cross-sectional examinations of solder joints upon failure indicate that cracks formed in (Cu,Ni)6Sn5 or Cu6Sn5 intermetallic compounds (IMCs) near the cathode side of the solder joint. Moreover, the ~52- μm-thick Sn-Ag-Cu solder after long-term current stressing has turned into a combination of ~80% Cu-Ni-Sn IMC and ~20% Sn-rich phases, which appeared in the form of large aggregates that in general were distributed on the cathode side of the solder joint.

  5. INFLUENCE OF IMC ON THE INTERFACE FAILURE OF TIN-SILVER-COPPER SOLDER JOINTS%金属间化合物对SnAgCu/Cu界面破坏行为的影响

    Institute of Scientific and Technical Information of China (English)

    李晓延; 严永长; 史耀武

    2005-01-01

    无铅焊接与封装是对新一代电子产品的基本要求,SnAgCu系合金是最有可能替代SnPb焊料的无铅焊料.SnAgCu-Cu界面金属间化合物(intermetallic components,IMC)的形成与生长对电子产品的性能和可靠性有重要影响.文中讨论SnAgCu-Cu界面IMC的形貌及组织演变,介绍SnAgCu-Cu界面IMC的形成、生长机理和表征方法,分析IMC对SnAgCu-Cu界面破坏行为的影响.

  6. Estudo da correlação do IMC e comprimento do intestino delgado em pacientes obesos submetidos à cirurgia bariátrica Correlation study of BMI and small intestine length in obese patients subjected to bariatric surgery

    Directory of Open Access Journals (Sweden)

    Paulo Afonso Nunes Nassif

    2009-09-01

    Full Text Available RACIONAL: Segundo a hipótese do intestino longo, o comprimento do intestino delgado estaria relacionado à obesidade. Existem dados evolutivos, anatômicos e neuroendócrinos em favor desta afirmação. OBJETIVOS: Verificar a medida do comprimento do intestino delgado em pacientes obesos submetidos à cirurgia bariátrica e analisar a correlação entre o seu tamanho e o IMC. MÉTODO: A casuística foi composta de 30 pacientes do Serviço de Obesidade do Hospital Universitário Evangélico de Curitiba, submetidos à cirurgia bariátrica no período de março a junho de 2009, e previamente avaliados, verificando peso, altura e IMC. A técnica cirúrgica foi a de Fobi-Capella. A mensuração do intestino delgado foi realizada desde a flexura duodenojejunal à junção ileocecal, durante o trans-operatório, utilizando uma pinça de manipulação intestinal, a qual foi marcada com a medida de 10 cm. As alças intestinais foram medidas na margem anti-mesentérica, aplicando-se tensão mínima necessária para retificar as mesmas. Os dados foram correlacionados e tabulados estatisticamente, utilizando-se o método de correlação de Pearson. RESULTADOS: A média do comprimento intestinal para o sexo masculino foi de 582,5 cm e para o sexo feminino de 509,1. A partir do cálculo do coeficiente de correlação de Pearson, confirmou-se a ausência de correlação entre IMC e comprimento do intestino delgado. CONCLUSÃO: Obteve-se uma média de tamanho intestinal de 528,7 cm para toda a amostra. O comprimento do intestino delgado não possuiu correspondência com o IMC, não sendo um fator de significância neste estudo.BACKGROUND: According to the hypothesis of long bowel, the length of small intestine is related to obesity. There are evolutionary, anatomics, neuroendocrines evidences in favor of this assertion. AIM: To check the measure of the small intestine length in overweight patients submitted to bariatric surgery and to analyze the correlation

  7. 整合营销传播是创建世界名牌的战略选择%Integrated Marketing Communication (IMC) Is Strategic Option of Creating World-famous Brand

    Institute of Scientific and Technical Information of China (English)

    孙持录

    2000-01-01

    本文首先分析了当前全球市场与竞争具有的市场个性化等四个特点,指出:整合营销传播(IMC)是创建世界名牌的战略选择,阐述了整合营销传播的精髓在于:市场导向性,系统整合性、控制反馈性,因而能适应当前全球的市场变化。同时建议我国企业在实施IMC时,应不失时机地建立顾客服务信息系统,进行组织再造,加强组织修炼,并注意跨文化沟通。

  8. IMC-PID Application to Control Exit Temperature of Heating Furnace%内模PID控制在加热炉出口温度控制中的应用

    Institute of Scientific and Technical Information of China (English)

    汤志武

    2013-01-01

    针对加热炉非线性、大滞后、大惯性的特点,采用内模PID控制方法对其出口温度进行控制.仿真与实践结果表明内模PID控制器具有良好的性能,出口温度能够得到良好地控制.%In petroleum refineries,heating furnace is commonly used though it consumes much energy; and the exit temperature as an important index of heating furnace control means great to follow-up technical process.Regarding the nonlinearity and large time delay and inertia of the heating furnace,the IMC-PID control method was employed to control the furnace' s exit temperature.Simulation results and application in-situ show that this method has good performance in the exit temperature control.

  9. IMC控制在双凸极发电机电压调节中的应用%Application of IMC Control on Voltage Regulation of A Doubly Salient Generator

    Institute of Scientific and Technical Information of China (English)

    陈志辉; 严仰光

    2000-01-01

    The paper presents the hardware platform of the digital voltage regulator,which is based on a DSP chip——TMS320C32,to fit the n eed for voltage regulation of a doubly-salient DC generator.And the IMC control algorithm os adopted in the hardware platform.In the experiment on a brushless doubly-salient DC generator,the digital voltage regulator results in good responses.%针对双凸极无刷直流发电机的调压要求,设计了以 TMS320C32为核心的数字调压器硬件平台。采用内模控制算法的数字调压在对双凸极无刷直 流发电机进行调压实验的过程中,取得了良好的控制效果。

  10. Metallurgical challenges in microelectronic 3D IC packaging technology for future consumer electronic products

    Institute of Scientific and Technical Information of China (English)

    K.; N.; TU; TIAN; Tian

    2013-01-01

    Metallurgical challenges in controlling the microstructural stability of Cu and solder microbumps in 3D IC packaging technol-ogy are discussed. Using uni-directional <111> oriented nanotwinned Cu, the controlled growth of oriented Cu6Sn5 on the nanotwinned Cu and its transformation to Cu3Sn without Kirkendall voids have been achieved. In order to join a stack of Si chips into a 3D device, multiple reflows of solder microbumps may be required; we consider localized heating to do so by the use of self-sustained explosive reaction in multi-layered Al/Ni thin films of nano thickness. It avoids re-melting of those solder joints which have been formed already in the 3D stacking structure.

  11. Nucleation and Growth of Cu-Al Intermetallics in Al-Modified Sn-Cu and Sn-Ag-Cu Lead-Free Solder Alloys

    Science.gov (United States)

    Reeve, Kathlene N.; Anderson, Iver E.; Handwerker, Carol A.

    2015-03-01

    Lead-free solder alloys Sn-Cu (SC) and Sn-Ag-Cu (SAC) are widely used by the microelectronics industry, but enhanced control of the microstructure is needed to improve solder performance. For such control, nucleation and stability of Cu-Al intermetallic compound (IMC) solidification catalysts were investigated by variation of the Cu (0.7-3.0 wt.%) and Al (0.0-0.4 wt.%) content of SC + Al and SAC + Al alloys, and of SAC + Al ball-grid array (BGA) solder joints. All of the Al-modified alloys produced Cu-Al IMC particles with different morphologies and phases (occasionally non-equilibrium phases). A trend of increasing Cu-Al IMC volume fraction with increasing Al content was established. Because of solidification of non-equilibrium phases in wire alloy structures, differential scanning calorimetry (DSC) experiments revealed delayed, non-equilibrium melting at high temperatures related to quenched-in Cu-Al phases; a final liquidus of 960-1200°C was recorded. During cooling from 1200°C, the DSC samples had the solidification behavior expected from thermodynamic equilibrium calculations. Solidification of the ternary alloys commenced with formation of ternary β and Cu-Al δ phases at 450-550°C; this was followed by β-Sn, and, finally, Cu6Sn5 and Cu-Al γ1. Because of the presence of the retained, high-temperature phases in the alloys, particle size and volume fraction of the room temperature Cu-Al IMC phases were observed to increase when the alloy casting temperature was reduced from 1200°C to 800°C, even though both temperatures are above the calculated liquidus temperature of the alloys. Preliminary electron backscatter diffraction results seemed to show Sn grain refinement in the SAC + Al BGA alloy.

  12. Optimization of the Ni(P) Thickness for an Ultrathin Ni(P)-Based Surface Finish in Soldering Applications

    Science.gov (United States)

    Ho, C. E.; Wang, S. J.; Fan, C. W.; Wu, W. H.

    2014-01-01

    The effects of the Ni(P) thickness δ Ni(P) on the interfacial reaction between an Sn-3Ag-0.5Cu solder and an Au/Pd(P)/Ni(P)/Cu pad (thickness: 0.05/0.05/0.1-0.3/20 μm) and the resulting mechanical properties were investigated using scanning electron microscopy equipped with an electron backscatter diffraction system, a focused ion beam system, electron probe microanalysis, and high-speed ball shear (HSBS) testing. Regardless of δ Ni(P), all of the Au/Pd(P)/Ni(P) surface finishes examined were completely exhausted in one reflow, exposing the Cu pad underneath the solder. Cu6Sn5 dissolved with various Ni contents, termed (Cu,Ni)6Sn5, was the dominant intermetallic compound (IMC) species at the solder/Cu interface. Additionally, Ni2SnP and Ni3P IMCs might form with the (Cu,Ni)6Sn5 in the thick Ni(P) case, i.e., δ Ni(P) = 0.3 μm, and the two IMCs (Ni2SnP and Ni3P) were gradually eliminated from the interface after multiple reflows. A mass balance analysis indicated that the growth of the Ni-containing IMCs, rather than the dissolution of the metallization pad, played a key role in the Ni(P) exhaustion. The HSBS test results indicated that the mechanical strength of the solder joints was also δ Ni(P) dependent. The combined results of the interfacial reaction and the mechanical evaluation provided the optimal δ Ni(P) value for soldering applications.

  13. Studies on in situ particulate reinforced tin-silver composite solders relevant to thermomechanical fatigue issues

    Science.gov (United States)

    Choi, Sunglak

    2001-07-01

    Global pressure based on environmental and health concerns regarding the use of Pb-bearing solder has forced the electronics industry to develop Pb-free alternative solders. Eutectic Sn-Ag solder has received much attention as a potential Pb-free candidate to replace Sn-Pb solder. Since introduction of surface mount technology, packaging density increased and the electronic devices became smaller. As a result, solders in electronic modules are forced to function as a mechanical connection as well as electrical contact. Solders are also exposed to very harsh service conditions such as automotive under-the-hood and aerospace applications. Solder joints experience thermomechanical fatigue, i.e. interaction of fatigue and creep, during thermal cycling due to temperature fluctuation in service conditions. Microstructural study on thermomechanical fatigue of the actual eutectic Sn-Ag and Sn-4Ag-0.5Cu solder joints was performed to better understand deformation and damage accumulation occurring during service. Incorporation of reinforcements has been pursued to improve the mechanical and particularly thermomechanical behavior of solders, and their service temperature capability. In-situ Sn-Ag composite solders were developed by incorporating Cu 6Sn5, Ni3Sn4, and FeSn2 particulate reinforcements in the eutectic Sn-Ag solder in an effort to enhance thermomechanical fatigue resistance. In-situ composite solders were investigated on the growth of interfacial intermetallic layer between solder and Cu substrate growth and creep properties. Solder joints exhibited significant deformation and damage on free surface and interior regions during thermomechanical fatigue. Cracks initiated on the free surface of the solder joints and propagated toward interior regions near the substrate of the solder joint. Crack grew along Sn grain boundaries by grain boundary sliding. There was significant residual stress within the solder joint causing more damage. Presence of small amount of Cu

  14. 电迁移对Ni/Sn3.0Ag0.5Cu/Cu焊点界面反应的影响%EFFECT OF ELECTROMIGRATION ON INTERFACIAL REACTION IN Ni/Sn3.0Ag0.5Cu/Cu FLIP CHIP SOLDER JOINTS

    Institute of Scientific and Technical Information of China (English)

    黄明亮; 陈雷达; 周少明

    2012-01-01

    The effect of electromigration (EM) on the interfacial reaction in Ni/Sn3.0Ag0.5Cu/Cu solder joints was investigated under a current density of 5.0 ×l03 A/cm2 at 150 ℃ All solder joints were aged at 150 ℃ for comparison purpose. It has been found that the (Cu,Ni)6Sn5 intermetallic compounds (IMCs) form at both soIder/Ni and solder/Cu interfaces in the as-reflowed state. During aging at 150 ℃, the thickness of interfacial IMC increases with increasing aging time, and no interfacial IMC transformation occurs even after aging for 800 h. The flowing direction of electrons plays an important role in Cu consumption. When electrons flow from printed circuit board (PCB) to chip, the current crowding effect induces a rapid and localized dissolution of Cu pad on PCB and a formation of microcrack at the Sn3.0Ag0.5Cu/(Cu, Ni)6Sn5 interface. The dissolved Cu atoms are driven towards anode by EM, and a large amount of Cu6Sn5 IMC particles form in solder matrix along the flowing direction of electrons. When electrons flow from chip to PCB, no obvious consumption of Ni underbump metallogy (UBM) has been observed and few Cu6Sn5 IMC particles form in solder matrix near the anode interface. There is no evidence of failure induced by EM in solder joints even after EM for 800 h. To sum up, EM enhances the growth of interfacial (Cu, Ni)6Sn5 at anode side, no matter how the direction of electrons is. The interfacial IMC at anode side is thicker than that at cathode side. The Ni/Sn3.0Ag0.5Cu/Cu solder joint is prone to fail when electrons flowing from Cu to Ni.%研究了温度为150℃,电流密度为5.0×103 A/cm2的条件下电迁移对Ni/Sn3.0Ag0.5Cu/Cu焊点界面反应的影响.回流焊后在Sn3.0Ag0.5Cu/Ni和Sn3.0Ag0.5Cu/Cu的界面上均形成了(Cu,Ni)6Sn5型化合物.时效过程中界面化合物随时效时间增加而增厚,时效800 h后两端的化合物并没有发生转变,仍为(Cu,Ni)6Sn5型.电流方向对Cu基板的消耗起着决定作用.当电子从基板

  15. Asociación entre periodontitis crónica, interleuquina -6 (IL-6 e índice de masa corporal (IMC en embarazadas Association between chronic periodontitis, interleukin-6 (IL-6 and body mass index (BMI in pregnant women

    Directory of Open Access Journals (Sweden)

    S Mella

    2011-12-01

    Full Text Available Objetivo: Determinar si la condición clínica periodontal materna, el índice de masa corporal (IMC y su variación durante el embarazo, se asocian con marcadores de inflamación sistémica: interleuquina-6 (IL-6, factor de necrosis tumoral alfa (TNF- y proteína C reactiva (PCR a nivel plasmático. Material y Método: Estudio clínico que analizó una cohorte de 56 embarazadas entre 18 y 38 años de edad (promedio 27.9 ± 7.04 años, derivadas de la unidad de medicina perinatal en el centro de salud docente asistencial (CESA de la Universidad de los Andes. Todas ellas consintieron voluntariamente su participación en el estudio. En cada trimestre de embarazo, se les realizó un examen periodontal completo, consistente en la determinación de los niveles de inserción clínica, profundidad al sondaje, índice de higiene y sangrado en seis sitios por cada pieza dentaria, excluyendo terceros molares. Adicionalmente, en cada control se obtuvieron muestras de sangre periférica para la determinación de los mediadores proinflamatorios mediante técnica de ELISA. El diagnóstico periodontal y los niveles de mediadores inflamatorios fueron relacionados con la variación del IMC durante el embarazo. Resultados: Las embarazadas con periodontitis crónica presentaron una mayor variación y aumento del índice de masa corporal (p=0.039 y niveles de IL-6 (p=0.026 en comparación con las mujeres embarazadas con gingivitis. Conclusiones: En esta serie de pacientes, se demostró una asociación entre el diagnóstico clínico de periodontitis durante el embarazo con un aumento plasmático de IL-6, así como también una asociación entre un aumento del IMC con los niveles plasmáticos de PCR.Objective: To determine if maternal periodontal clinical status, body mass index (BMI and its variation during pregnancy are associated with increased levels of interleukin-6 (IL-6, tumor necrosis factor alpha (TNF- and C-reactive protein (CRP in plasma. Material and

  16. International BMI-for-age references underestimate thinness and overestimate overweigth and obesity in Bolivian adolescents Las referencias internacionales de IMC por edad subestiman delgadez y sobreestiman sobrepeso y obesidad en adolescentes bolivianos

    Directory of Open Access Journals (Sweden)

    A. Baya Botti

    2010-06-01

    Full Text Available Background: Since no growth standards for adolescents exist and a single reference applicable everywhere is still in debate, it is recognized that the best reference should be derived from the growth pattern of the healthy population that will use it. In 2007 a study developed references for body mass index for 12th to 18th y Bolivian school adolescent (BAP. Objectives: To compare nutritional status outcomes applying BMI references from the BAP, the Center for Disease Control and Prevention CDC 2000, the International Task Force (IOTF, and the 2007 WHO, to determine appropriateness of use in Bolivian adolescents. Subjects/methods: References were applied in 3306 adolescents, 45.0% male, 55% female, 12th to 18th y selected from a nationally representative sample. Results: Main findings reveal that the CDC and the 2007 WHO underestimate underweight (p Introducción: Puesto que no existen estándares de crecimiento para adolescentes y la aplicación de una sola referencia a nivel mundial es aún debatible, se reconoce que la mejor referencia es aquella derivada del patrón de crecimiento de la población saludable en la que será posteriormente utilizada. Por ello en 2007 se efectuó un estudio para desarrollar la Referencia Boliviana de IMC poredad (BAP para adolescentes entre 12 a 18 años. Objetivos: Comparar la clasificación de adolescentes por categorías nutricionales, aplicando las referencias de IMC boliviano (BAP, la referencia CDC 2000, los puntosde corte de IOTF y de la OMS, 2007. Métodos y población: Las referencias se aplicaron a los datos medidos de peso y talla de 3.306 adolescentes, 45% varones y 55% mujeres seleccionados de una muestrarepresentativa de la población boliviana. Resultados: Se observa que CDC y OMS 2007 subestiman la prevalencia de delgadez (P < 0,001 mientras que las tres referencias internacionales sobreestiman el sobrepeso(p < 0,001 con variaciones por edad y género. Conclusión: Se recomienda al personal de

  17. Model uncertainty bound of first order lag process with dead time and IMC controller design for robust performance%FOPDT的模型不确定性界和内模控制器 鲁棒性能设计

    Institute of Scientific and Technical Information of China (English)

    龚剑平

    2001-01-01

    给出了一种求取一阶加纯滞后对象(FOPDT)不确定性界的方法,与Laughlin等人提出的方法相比,具有高精确度和广泛的应用范围。将文中给出的模型不确定性界应用于按鲁棒性能要求的内模控制器设计,取得了令人满意的结果。%A method of calculating model uncertainty bound for the first order lag process with dead time(FOPDT) is given in this paper. Camparing with the method developed by Laughlin et al, the accuracy of the method in this paper is much higher, and the application scope is more extensive. Using the method given in this paper, the satisfied result of the IMC controller design for robost performance is also obtained.

  18. 奇瑞QQ VS与大众GOL--评IMC在汽车营销中的实践%Cherry QQ VS Volkswagen GOL-comment on IMC during practice in auto sales

    Institute of Scientific and Technical Information of China (English)

    陈宪

    2004-01-01

    @@ 中国加入WTO之后,无论是国外还是国内,各种资本纷纷进入汽车行业,新车型频频推出,价格战连绵不断,形成了一种群雄逐鹿的强大竞争态势.在这种巨大的竞争压力下,大部分汽车厂家开始尝试运用公关、广告、促销、降价等营销手段,打造强势汽车品牌.这标志着中国汽车业真正进入了营销时代,各大汽车厂商能不能在这种激烈的竞争中站稳脚跟取决于营销.本文将通过奇瑞QQ和大众GOL一成一败两个案例讨论IMC(整合营销传播)在汽车营销中的应用,希望能给汽车营销提供一点借鉴.

  19. 理论建构与理论批评的互动——美国整合营销传播理论研究二十年综述%Interaction of Theoretical Construction and Theoretical Criticism——A Review of Twenty Years of American IMC Theory Research

    Institute of Scientific and Technical Information of China (English)

    黄迎新

    2010-01-01

    "整合营销传播"(IMC)从概念到话语只花了十年时间,这一阶段以理论建构为主.在随后的十年,美国IMC研究集中在"理论"和"实践"两大主题上,对于"什么是IMC"及"IMC是否有价值"学术界仍存在较大分歧,集中体现在"IMC是管理时尚还是理论范式"的争论上,这一阶段以理论批评为主,正是理论批评与理论建构互动,推动IMC向理论范式迈进.美国IMC理论研究路径对中国学者们的研究深具启发意义.

  20. Innovation in Layer-by-Layer Assembly.

    Science.gov (United States)

    Richardson, Joseph J; Cui, Jiwei; Björnmalm, Mattias; Braunger, Julia A; Ejima, Hirotaka; Caruso, Frank

    2016-12-14

    Methods for depositing thin films are important in generating functional materials for diverse applications in a wide variety of fields. Over the last half-century, the layer-by-layer assembly of nanoscale films has received intense and growing interest. This has been fueled by innovation in the available materials and assembly technologies, as well as the film-characterization techniques. In this Review, we explore, discuss, and detail innovation in layer-by-layer assembly in terms of past and present developments, and we highlight how these might guide future advances. A particular focus is on conventional and early developments that have only recently regained interest in the layer-by-layer assembly field. We then review unconventional assemblies and approaches that have been gaining popularity, which include inorganic/organic hybrid materials, cells and tissues, and the use of stereocomplexation, patterning, and dip-pen lithography, to name a few. A relatively recent development is the use of layer-by-layer assembly materials and techniques to assemble films in a single continuous step. We name this "quasi"-layer-by-layer assembly and discuss the impacts and innovations surrounding this approach. Finally, the application of characterization methods to monitor and evaluate layer-by-layer assembly is discussed, as innovation in this area is often overlooked but is essential for development of the field. While we intend for this Review to be easily accessible and act as a guide to researchers new to layer-by-layer assembly, we also believe it will provide insight to current researchers in the field and help guide future developments and innovation.

  1. Sn-Ag-Cu无铅钎料粉末与合金的组织及钎焊性能对比%Microstructure and Solderability of Sn-Ag-Cu Lead-free Solder Powder and Alloy

    Institute of Scientific and Technical Information of China (English)

    许天旱; 王党会

    2009-01-01

    利用自行设计的超音速雾化制粉装置制备了Sn-3Ag-2.8Cu 无铅焊锡粉末,并将不同介质雾化的粉末组织和普通合金组织进行对比,同时选择一种综合性能良好的粉末,将其钎焊性能和普通合金进行对比.结果表明,氮气雾化粉末比空气雾化粉末具有更高的凝固速度;雾化粉末组织更细小,主要由基体上弥散分布的多边形Cu6Sn5 IMC 和粒状Ag3Sn IMC组成;粉末比普通合金与铜基板形成的IMC更不规则,且扩散层与基板的界面更模糊;雾化粉末的蠕变断裂寿命显著高于普通合金.因此,Sn-3Ag-2.8Cu无铅焊锡粉末性能优于普通合金.

  2. SnAgCu无铅焊点的电迁移行为研究%Electromigration behavior of SnAgCu lead-free soldering point

    Institute of Scientific and Technical Information of China (English)

    何洪文; 徐广臣; 郝虎; 雷永平; 郭福

    2007-01-01

    电迁移引发的焊点失效已经成为当今高集成度电子封装中的最严重的可靠性问题之一.应用SnAgCu无铅焊膏焊接微米级铜线,进行电迁移实验.结果表明:焊点形貌从原来的光滑平整变得凹凸不平,阴极处出现了裂纹和孔洞,并且在铜基板和Cu6Sn5金属间化合物(IMC)之间出现薄薄的一层Cu3Sn金属间化合物,由ImageJ软件测量其平均厚度约为2.11 μm;而在阳极附近没有明显的Cu3Sn金属间化合物形成.

  3. Aplicação do teste de informação, memória e concentração (IMC ao estudo epidemiológico de demência senil em Fortaleza

    Directory of Open Access Journals (Sweden)

    G. S. B. Viana

    1991-09-01

    Full Text Available O presente trabalho teve por objetivo verificar a ocorrência de demência senil em amostra de pessoas de 65 e mais anos de idade residentes no Município de Fortaleza. Foram testados 865 idosos, a partir do teste de Informação, Memória e Concentração, IMC (teste de Hachinski, modificado, que aborda aspectos concernentes à identificação da pessoa, à memória de fatos atuais e remotos e à concentração, determinando os estados demenciais em função do número e grau de respostas numa seqüência programada e previamente testada quanto à sensibilidade e especificidade. Analisando-se os resultados quanto a idade, sexo e condição social, evidenciou-se uma prevalência de 8,4% de demência senil no conjunto geral, com diferença não-significativa na faixa de 75 e mais anos de idade (9,3%, comparada ao grupo de 65 a 74 anos (7,5%. Os percentuais foram semelhantes para homens e mulheres: 8,7% e 8,3%, respectivamente. Quanto à condição social, foi verificado um aumento progressivo nas proporções de estados demenciais, desde 4,2% para o estrato A/B (abastados, 6,9% para o grupo C (nível intermediário e 10,3% no nível D/E correspondente ao estrato de pessoas economicamente desprivilegiadas. Estes resultados, entretanto, deverão ser vistos com cena reserva, dado o grau de recusa por ocasião das entrevistas, especialmente nos estratros A/B (19,3% e D/E (9,3%.The objective of the present paper was to verify the occurrence of senile dementia in the city of Fortaleza, Brazil. A screening test, the Information, Memory and Concentration Test (IMC, was applied to 865 persons (65 years old and older. The Test includes questions on personal identification, recent and remote memory and concentration. Dementia was determined as a function of the total score obtained by the person in the test previously examined as far as sensitivity and specificity are concerned. The results were analysed according to age, sex and social strata. It was

  4. Insulin-like growth factor-I receptor (IGF-IR) targeting with monoclonal antibody cixutumumab (IMC-A12) inhibits IGF-I action in endometrial cancer cells.

    Science.gov (United States)

    Attias-Geva, Zohar; Bentov, Itay; Ludwig, Dale L; Fishman, Ami; Bruchim, Ilan; Werner, Haim

    2011-07-01

    Specific insulin-like growth factor-I receptor (IGF-IR) targeting emerged in recent years as a promising therapeutic strategy in cancer. Endometrial cancer is the most common gynaecological cancer in the Western world. The aim of this study was to evaluate the potential of cixutumumab (IMC-A12, ImClone Systems), a fully human monoclonal antibody against the IGF-IR, to inhibit IGF-I-mediated biological actions and cell signalling events in four endometrial carcinoma-derived cell lines (ECC-1, Ishikawa, USPC-1 and USPC-2). Our results demonstrate that cixutumumab was able to block the IGF-I-induced autophosphorylation of the IGF-IR. In addition, the PI3K and MAPK downstream signalling pathways were also inactivated by cixutumumab in part of the cell lines. Prolonged (24h and 48h) exposures to cixutumumab reduced IGF-IR expression. Furthermore, confocal microscopy of GFP-tagged receptors shows that cixutumumab treatment led to IGF-IR redistribution from the cell membrane to the cytoplasm. Antiapoptotic effects were evaluated by cleavage of caspase 3 and PARP, and mitogenicity and transformation by proliferation and cell cycle assays. Results obtained showed that cixutumumab abrogated the IGF-I-stimulated increase in proliferation rate, and increased caspase-3 and PARP cleavage, two markers of apoptosis. Of importance, cixutumumab had no effect neither on insulin receptor (IR) expression nor on IGF-I activation of IR. In summary, in a cellular model of endometrial cancer cixutumumab was able to inhibit the IGF-I-induced activation of intracellular cascades, apoptosis and proliferation.

  5. Gidon Kremer sai IMC-UNESCO auhinna

    Index Scriptorium Estoniae

    2001-01-01

    Rahvusvaheline muusikanõukogu ja UNESCO kuulutasid tänavu üheks oma ühise muusikaauhinna saajateks Gidon Kremeri, kes esineb ka 21. augustil Estonia kontserdisaalis koos Schleswig-Holsteini festivaliorkestriga

  6. MICROSTRUCTURE ANALYSIS OF INTERFACIAL LAYER WITH TUNGSTEN INERT GAS WELDING-BRAZING JOINT OF ALUMINUM ALLOY/STAINLESS STEEL%铝合金/不锈钢钨极氩弧熔-钎焊接头界面层的微观结构分析

    Institute of Scientific and Technical Information of China (English)

    林三宝; 宋建岭; 杨春利; 马广超

    2009-01-01

    Against the background of the required weight reduction in transportation through lightweight construction, the application of hybrid structures, where aluminum alloy and steel are jointed together, has a high technical and economical potential. But jointing of material combinations of aluminum alloy and steel is problematic by fusion welding since brittle intermetallic compounds (IMCs) are formed between aluminum alloy and steel. Nowadays, tungsten inert gas (TIG) welding-brazing offers a great potential for aluminum alloy and steel jointing. In this process, the sheet and filler metal are heated or melted by TIG heat, and the joint has a dual characteristic: in aluminum alloy side it is a welding joint, while in steel side it is a brazing joint. However, in the dynamic heating process, the heating temperature changes so quickly and the reaction time between the liquid filler metal and solid steel is so short that it is more difficult to control the IMC layer's growth, predominantly its thickness and microstructures. Most of past reports about the brazing of aluminum alloy and steel indicate Al-Fe binary IMC layers, e.g., Fe_2Al_5 and FeAl_3, formed in the brazing joint, which are detrimental to the mechanical properties of the joint. Si additions are used to limit the growth of the brittle Al-Fe IMC layer between aluminum alloy and steel by replacing Al-Fe phases with less detrimental Al-Fe-Si phases in aluminizing and furnace brazing of aluminum alloy and steel. By now, there have been few reports of investigating the interfacial layer of TIG welding-brazing joint of aluminum alloy and stainless steel. In this paper, a butt TIG welding-brazing joint of aluminum alloy/stainless steel was formed using Al-Si eutectic filler wire with modified Noclock flux precoated on a steel surface. The microstructure characteristics of the welded seam-steel interfacial layer were analyzed by OM, SEM and EDS and its mechanical properties were measured by dynamic ultra

  7. Rapid Solidification of Sn-Cu-Al Alloys for High-Reliability, Lead-Free Solder: Part I. Microstructural Characterization of Rapidly Solidified Solders

    Science.gov (United States)

    Reeve, Kathlene N.; Choquette, Stephanie M.; Anderson, Iver E.; Handwerker, Carol A.

    2016-12-01

    Particles of Cu x Al y in Sn-Cu-Al solders have previously been shown to nucleate the Cu6Sn5 phase during solidification. In this study, the number and size of Cu6Sn5 nucleation sites were controlled through the particle size refinement of Cu x Al y via rapid solidification processing and controlled cooling in a differential scanning calorimeter. Cooling rates spanning eight orders of magnitude were used to refine the average Cu x Al y and Cu6Sn5 particle sizes down to submicron ranges. The average particle sizes, particle size distributions, and morphologies in the microstructures were analyzed as a function of alloy composition and cooling rate. Deep etching of the samples revealed the three-dimensional microstructures and illuminated the epitaxial and morphological relationships between the Cu x Al y and Cu6Sn5 phases. Transitions in the Cu6Sn5 particle morphologies from faceted rods to nonfaceted, equiaxed particles were observed as a function of both cooling rate and composition. Initial solidification cooling rates within the range of 103 to 104 °C/s were found to be optimal for realizing particle size refinement and maintaining the Cu x Al y /Cu6Sn5 nucleant relationship. In addition, little evidence of the formation or decomposition of the ternary- β phase in the solidified alloys was noted. Solidification pathways omitting the formation of the ternary- β phase agreed well with observed room temperature microstructures.

  8. Redução da pressão arterial, da IMC e da glicose após treinamento aeróbico em idosas com diabete tipo 2

    Directory of Open Access Journals (Sweden)

    Luciana Zaranza Monteiro

    2010-10-01

    Full Text Available FUNDAMENTO: O processo de envelhecimento associa-se ao desenvolvimento de várias doenças, que podem ser amenizadas pela prática de atividades físicas. O treinamento aeróbico é um meio efetivo para manter e melhorar as funções cardiovasculares. Além disso, desempenha um papel fundamental na prevenção e tratamento de diversas doenças crônico-degenerativas, em especial o diabete melito. OBJETIVO: Verificar os efeitos de 13 semanas de treinamento aeróbico sobre a pressão arterial, o índice de massa corpórea e a glicemia em idosas com diabete tipo 2. MÉTODOS: Onze mulheres idosas diabéticas (61,0 ± 9,1 anos de idade, sedentárias, realizaram 13 semanas de treinamento aeróbico, compondo o grupo G2. Onze idosas (60,2 ± 6,8 anos de idade controladas não realizaram exercícios físicos durante a pesquisa, constituindo o grupo-controle (G1. O grupo G1 foi submetido somente a orientações educativas uma vez na semana, e o grupo G2, a caminhadas três vezes na semana. RESULTADOS: Houve redução significativa da glicemia e da pressão arterial diastólica nos dois grupos. Não foram encontradas reduções significativas no IMC após o treinamento aeróbico em ambos os grupos. CONCLUSÃO: Treze semanas de treinamento aeróbico foi suficiente para promover reduções significativas na pressão arterial diastólica e glicemia, portanto, esse tipo de exercício reduz os fatores de risco para doenças cardiovasculares e metabólicas.

  9. Fatigue Test on Bogie Frame of Straddle-Type Monorail Train Based on IMC%基于IMC数采器的跨座式单轨列车转向架疲劳试验

    Institute of Scientific and Technical Information of China (English)

    文孝霞; 杜子学; 姜保军; 李吉惠

    2013-01-01

    Straddle-type monorail train bogie frame was regarded as the test object. The strain gauge was layout at dangerous situation of the frame. By using the half-bridge wiring method and applying portable data collector CI of IMC, the stress time history data of the measuring point placed the dangerous situation was collected at 30,35 ,40,45 km/h speed. After the collected data was cut, filter, smooth, delayed treatment and discarded invalid amplitude, the program of rain-flow counting and S-N material curve were complied. By the program, the fatigue damaged values under different speed, different filter were calculated. Based on the test data, the function of damaged value and speed were set up, and the fatigue life in different running speed was predicted.%以跨坐式单轨列车转向架构架为试验对象,在构架危险部位布置应变片.采用半桥路接线法,运用IMC公司便携式数采器CI,对车辆在30,35,40,45 km/h运行速度下危险部位测点的应力时间历程数据实时采集.对采集的数据进行截取、滤波、平滑、迟滞处理及载荷谱无效幅值舍弃后,编制雨流计数程序及材料的S-N材料特性程序,计算出该构架在不同时速、不同滤波情况下疲劳损伤值.根据测试的数据,拟合出损伤值与速度之间的函数关系,预测了转向架构架在不同运行速度下的疲劳寿命.

  10. VSWI Wetlands Advisory Layer

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset represents the DEC Wetlands Program's Advisory layer. This layer makes the most up-to-date, non-jurisdictional, wetlands mapping avaiable to the public...

  11. Basic Ozone Layer Science

    Science.gov (United States)

    Learn about the ozone layer and how human activities deplete it. This page provides information on the chemical processes that lead to ozone layer depletion, and scientists' efforts to understand them.

  12. Ozone Layer Protection

    Science.gov (United States)

    ... Search Search Ozone Layer Protection Share Facebook Twitter Google+ Pinterest Contact Us Ozone Layer Protection Welcome to ... Managing Refrigerant Emissions Stationary Refrigeration and Air Conditioning Car and Other Mobile Air Conditioning GreenChill Partnership Responsible ...

  13. Piezoelectric Resonator with Two Layers

    Science.gov (United States)

    Stephanou, Philip J. (Inventor); Black, Justin P. (Inventor)

    2013-01-01

    A piezoelectric resonator device includes: a top electrode layer with a patterned structure, a top piezoelectric layer adjacent to the top layer, a middle metal layer adjacent to the top piezoelectric layer opposite the top layer, a bottom piezoelectric layer adjacent to the middle layer opposite the top piezoelectric layer, and a bottom electrode layer with a patterned structure and adjacent to the bottom piezoelectric layer opposite the middle layer. The top layer includes a first plurality of electrodes inter-digitated with a second plurality of electrodes. A first one of the electrodes in the top layer and a first one of the electrodes in the bottom layer are coupled to a first contact, and a second one of the electrodes in the top layer and a second one of the electrodes in the bottom layer are coupled to a second contact.

  14. Building biomedical materials layer-by-layer

    Directory of Open Access Journals (Sweden)

    Paula T. Hammond

    2012-05-01

    Full Text Available In this materials perspective, the promise of water based layer-by-layer (LbL assembly as a means of generating drug-releasing surfaces for biomedical applications, from small molecule therapeutics to biologic drugs and nucleic acids, is examined. Specific advantages of the use of LbL assembly versus traditional polymeric blend encapsulation are discussed. Examples are provided to present potential new directions. Translational opportunities are discussed to examine the impact and potential for true biomedical translation using rapid assembly methods, and applications are discussed with high need and medical return.

  15. Multi-layers castings

    Directory of Open Access Journals (Sweden)

    J. Szajnar

    2010-01-01

    Full Text Available In paper is presented the possibility of making of multi-layers cast steel castings in result of connection of casting and welding coating technologies. First layer was composite surface layer on the basis of Fe-Cr-C alloy, which was put directly in founding process of cast carbon steel 200–450 with use of preparation of mould cavity method. Second layer were padding welds, which were put with use of TIG – Tungsten Inert Gas surfacing by welding technology with filler on Ni matrix, Ni and Co matrix with wolfram carbides WC and on the basis on Fe-Cr-C alloy, which has the same chemical composition with alloy, which was used for making of composite surface layer. Usability for industrial applications of surface layers of castings were estimated by criterion of hardness and abrasive wear resistance of type metal-mineral.

  16. The Equatorial Ekman Layer

    CERN Document Server

    Marcotte, Florence; Soward, Andrew

    2016-01-01

    The steady incompressible viscous flow in the wide gap between spheres rotating about a common axis at slightly different rates (small Ekman number E) has a long and celebrated history. The problem is relevant to the dynamics of geophysical and planetary core flows, for which, in the case of electrically conducting fluids, the possible operation of a dynamo is of considerable interest. A comprehensive asymptotic study, in the limit E<<1, was undertaken by Stewartson (J. Fluid Mech. 1966, vol. 26, pp. 131-144). The mainstream flow, exterior to the E^{1/2} Ekman layers on the inner/outer boundaries and the shear layer on the inner sphere tangent cylinder C, is geostrophic. Stewartson identified a complicated nested layer structure on C, which comprises relatively thick quasi-geostrophic E^{2/7} (inside C) and E^{1/4} (outside C) layers. They embed a thinner E^{1/3} ageostrophic shear layer (on C), which merges with the inner sphere Ekman layer to form the E^{2/5} Equatorial Ekman layer of axial length E^{...

  17. The Application of Layer Theory to Design: The Control Layer

    Science.gov (United States)

    Gibbons, Andrew S.; Langton, Matthew B.

    2016-01-01

    A theory of design layers proposed by Gibbons ("An Architectural Approach to Instructional Design." Routledge, New York, 2014) asserts that each layer of an instructional design is related to a body of theory closely associated with the concerns of that particular layer. This study focuses on one layer, the control layer, examining…

  18. Multi-layer coatings

    Energy Technology Data Exchange (ETDEWEB)

    Maghsoodi, Sina; Brophy, Brenor L.; Abrams, Ze' ev R.; Gonsalves, Peter R.

    2016-06-28

    Disclosed herein are coating materials and methods for applying a top-layer coating that is durable, abrasion resistant, highly transparent, hydrophobic, low-friction, moisture-sealing, anti-soiling, and self-cleaning to an existing conventional high temperature anti-reflective coating. The top coat imparts superior durability performance and new properties to the under-laying conventional high temperature anti-reflective coating without reducing the anti-reflectiveness of the coating. Methods and data for optimizing the relative thickness of the under-layer high temperature anti-reflective coating and the top-layer thickness for optimizing optical performance are also disclosed.

  19. Addressing Ozone Layer Depletion

    Science.gov (United States)

    Access information on EPA's efforts to address ozone layer depletion through regulations, collaborations with stakeholders, international treaties, partnerships with the private sector, and enforcement actions under Title VI of the Clean Air Act.

  20. Structured luminescence conversion layer

    Science.gov (United States)

    Berben, Dirk; Antoniadis, Homer; Jermann, Frank; Krummacher, Benjamin Claus; Von Malm, Norwin; Zachau, Martin

    2012-12-11

    An apparatus device such as a light source is disclosed which has an OLED device and a structured luminescence conversion layer deposited on the substrate or transparent electrode of said OLED device and on the exterior of said OLED device. The structured luminescence conversion layer contains regions such as color-changing and non-color-changing regions with particular shapes arranged in a particular pattern.

  1. Layered circle packings

    Directory of Open Access Journals (Sweden)

    David Dennis

    2005-01-01

    Full Text Available Given a bounded sequence of integers {d0,d1,d2,…}, 6≤dn≤M, there is an associated abstract triangulation created by building up layers of vertices so that vertices on the nth layer have degree dn. This triangulation can be realized via a circle packing which fills either the Euclidean or the hyperbolic plane. We give necessary and sufficient conditions to determine the type of the packing given the defining sequence {dn}.

  2. Sugar-sweetened beverages consumption and BMI in Mexican adolescents: Mexican National Health and Nutrition Survey 2006 Consumo de bebidas azucaradas y su relación con el IMC en adolescentes mexicanos: Encuesta Nacional de Salud y Nutrición 2006

    Directory of Open Access Journals (Sweden)

    Alejandra Jiménez-Aguilar

    2009-01-01

    Full Text Available OBJECTIVE: To evaluate the association between the consumption of sugar-sweetened beverages (SSBs and body mass index (BMI in Mexican adolescents. MATERIAL AND METHODS: We analyzed the data of 10 689 adolescents (ages 10 to 19 years old who participated in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006. Consumption of SSBs (i.e. sodas, fruit beverages and sugar beverages was evaluated by means of a semi-quantitative food frequency questionnaire. BMI was calculated (kg/m². RESULTS: Mean age was 13.8 ± 2.7 years. Fifty percent were females. Mean BMI was 21.7 ± 4.5. Thirty percent of adolescents were overweight or obese. Ninety percent of adolescents consumed at least one SSB during the 7 days before the interview. The median consumption of SSBs was 0.89 portion per day. Multiple-linear regression analysis showed that for each portion of sodas consumed, a 0.17-point increase in BMI was observed in boys after adjusting for confounders (95% CI; 0.02-0.32, p 0.03. Positive interactions of SSB consumption with age and time watching TV were observed in boys. CONCLUSIONS: Consumption of sodas was positively associated with BMI in Mexican boys.OBJETIVO: Examinar la asociación entre el consumo de bebidas refrescantes azucaradas (BRA y el índice de masa corporal (IMC en adolescentes mexicanos. MATERIAL Y MÉTODOS: Se analizaron datos de 10 689 adolescentes (10 a 19 años de edad de la Encuesta Nacional de Salud y Nutrición 2006 (ENSANUT 2006. El consumo de bebidas refrescantes azucaradas (BRA: refrescos, bebidas de fruta y bebidas endulzadas se evaluó con un cuestionario semicuantitativo de frecuencia de consumo de alimentos. Se calculó el índice de masa corporal (kg/m². RESULTADOS: La media de edad fue de 13.8 ± 2.7 años. El 50.4% fueron mujeres. La media de IMC fue de 21.7 ± 4.5. Un 30% de los adolescentes presentó sobrepeso u obesidad. El 90% de los adolescentes consumieron al menos una BRA en los 7 días previos a la

  3. Superfluid Boundary Layer

    Science.gov (United States)

    Stagg, G. W.; Parker, N. G.; Barenghi, C. F.

    2017-03-01

    We model the superfluid flow of liquid helium over the rough surface of a wire (used to experimentally generate turbulence) profiled by atomic force microscopy. Numerical simulations of the Gross-Pitaevskii equation reveal that the sharpest features in the surface induce vortex nucleation both intrinsically (due to the raised local fluid velocity) and extrinsically (providing pinning sites to vortex lines aligned with the flow). Vortex interactions and reconnections contribute to form a dense turbulent layer of vortices with a nonclassical average velocity profile which continually sheds small vortex rings into the bulk. We characterize this layer for various imposed flows. As boundary layers conventionally arise from viscous forces, this result opens up new insight into the nature of superflows.

  4. Layered Systems Engineering Engines

    Science.gov (United States)

    Breidenthal, Julian C.; Overman, Marvin J.

    2009-01-01

    A notation is described for depicting the relationships between multiple, contemporaneous systems engineering efforts undertaken within a multi-layer system-of-systems hierarchy. We combined the concepts of remoteness of activity from the end customer, depiction of activity on a timeline, and data flow to create a new kind of diagram which we call a "Layered Vee Diagram." This notation is an advance over previous notations because it is able to be simultaneously precise about activity, level of granularity, product exchanges, and timing; these advances provide systems engineering managers a significantly improved ability to express and understand the relationships between many systems engineering efforts. Using the new notation, we obtain a key insight into the relationship between project duration and the strategy selected for chaining the systems engineering effort between layers, as well as insights into the costs, opportunities, and risks associated with alternate chaining strategies.

  5. Reinforcing the mineral layer

    Energy Technology Data Exchange (ETDEWEB)

    Pishchulin, V.V.; Kuntsevich, V.I.; Seryy, A.M.; Shirokov, A.P.

    1980-05-15

    A way of reinforcing the mineral layer includes drilling holes and putting in anchors that are longer than the width of the layer strip being extracted. It also includes shortening the anchors as the strip is mined and reinforcing the remaining part of the anchor in the mouth of the hole. To increase the productivity and safety of the work, the anchors are shortened by cutting them as the strip is mined and are reinforced through wedging. The device for doing this has auxilliary lengthwise grooves in the shaft located along its length at an interval equal to the width of the band being extracted.

  6. Improved electron transport layer

    DEFF Research Database (Denmark)

    2012-01-01

    The present invention provides: a method of preparing a coating ink for forming a zinc oxide electron transport layer, comprising mixing zinc acetate and a wetting agent in water or methanol; a coating ink comprising zinc acetate and a wetting agent in aqueous solution or methanolic solution...

  7. Physical layer network coding

    DEFF Research Database (Denmark)

    Fukui, Hironori; Popovski, Petar; Yomo, Hiroyuki

    2014-01-01

    Physical layer network coding (PLNC) has been proposed to improve throughput of the two-way relay channel, where two nodes communicate with each other, being assisted by a relay node. Most of the works related to PLNC are focused on a simple three-node model and they do not take into account...

  8. Layer-Cake Earth

    Science.gov (United States)

    Tedford, Rebecca; Warny, Sophie

    2006-01-01

    In this article, the authors offer a safe, fun, effective way to introduce geology concepts to elementary school children of all ages: "coring" layer cakes. This activity introduces the concepts and challenges that geologists face and at the same time strengthens students' inferential, observational, and problem-solving skills. It also addresses…

  9. EHD lubricating layer

    Energy Technology Data Exchange (ETDEWEB)

    Shvarts, I.A.

    1978-01-01

    The simplest model of an EHD lubricating layer consists of a unipolarly charged nonconducting viscous fluid between two parallel or slightly inclined nonconducting plates. The performance of such a layer is analyzed here on the basis of the fundamental EHD equations, with a plane-parallel approximation of the flow of a thin layer under a variable upper boundary. The results of the solution indicate that the bearing capacity of such a layer between parallel plates does not depend on the viscosity of the fluid, but is proportional to the energy density of the electric field in vacuum. With the plates not parallel, the bearing capacity depends on the mobility and the diffusion of the charged fluid particles. In either case the energy of the electric field can be made to compensate for the energy dissipation due to viscous friction, and in this case or with overcompensation such as EHD bearing becomes an EHD generator. Most valuable for practical applications are fluids with a high dielectric permittivity, such as ammonia and hydrogen chloride at cryogenic temperatures. 5 references, 1 figure.

  10. MITRE sensor layer prototype

    Science.gov (United States)

    Duff, Francis; McGarry, Donald; Zasada, David; Foote, Scott

    2009-05-01

    The MITRE Sensor Layer Prototype is an initial design effort to enable every sensor to help create new capabilities through collaborative data sharing. By making both upstream (raw) and downstream (processed) sensor data visible, users can access the specific level, type, and quantities of data needed to create new data products that were never anticipated by the original designers of the individual sensors. The major characteristic that sets sensor data services apart from typical enterprise services is the volume (on the order of multiple terabytes) of raw data that can be generated by most sensors. Traditional tightly coupled processing approaches extract pre-determined information from the incoming raw sensor data, format it, and send it to predetermined users. The community is rapidly reaching the conclusion that tightly coupled sensor processing loses too much potentially critical information.1 Hence upstream (raw and partially processed) data must be extracted, rapidly archived, and advertised to the enterprise for unanticipated uses. The authors believe layered sensing net-centric integration can be achieved through a standardize-encapsulate-syndicateaggregate- manipulate-process paradigm. The Sensor Layer Prototype's technical approach focuses on implementing this proof of concept framework to make sensor data visible, accessible and useful to the enterprise. To achieve this, a "raw" data tap between physical transducers associated with sensor arrays and the embedded sensor signal processing hardware and software has been exploited. Second, we encapsulate and expose both raw and partially processed data to the enterprise within the context of a service-oriented architecture. Third, we advertise the presence of multiple types, and multiple layers of data through geographic-enabled Really Simple Syndication (GeoRSS) services. These GeoRSS feeds are aggregated, manipulated, and filtered by a feed aggregator. After filtering these feeds to bring just the type

  11. Study on W2W Vacuum Package for MEMS Device%MEMS器件的W2 W真空封装研究

    Institute of Scientific and Technical Information of China (English)

    董艳

    2015-01-01

    A simple wafer-level vacuum packaging method based on W2W process was developed for MEMS device.The sold-er frames with Cu and Sn metallization layers were deposited on both MEMS device wafer and cap wafer with electroplating process. MEMS device wafer and cap wafer were kept for 10 min in vacuum of 0.01 Pa and at the temperature of 160℃to create vacuum. Then the wafers were bonded together through the inter diffusion process of elemental Cu and Sn by keeping for 30 min at 270℃and 4 MPa.The intermetallic Cu3Sn and Cu6Sn5 was confirmed by measuring the weight ratio of elemental Cu and Sn in bonding region.The strength of bonding area of single chip was characterized by shear testing,calculating shear strength for bonding area was 32.20 MPa.%开发了一种适于MEMS器件的基于W2W(圆片对圆片)工艺的简易的圆片级真空封装方法。通过电镀工艺在MEMS器件圆片和封盖圆片上各沉积含5μm Cu和1.5μm Sn金属层的键合环。器件圆片和封盖圆片在160℃及0.01 Pa的真空环境中保持10 min以形成真空,之后在270℃及4 MPa保持30 min通过Cu和Sn的互溶扩散工艺完成键合。测量键合区内Cu元素和Sn元素的重量比,证实形成了Cu3 Sn和Cu6 Sn5金属间化合物。通过剪切力测试对单个芯片的键合面强度进行标定,计算剪切强度达32.20 MPa。

  12. Boundary layer transition studies

    Science.gov (United States)

    Watmuff, Jonathan H.

    1995-02-01

    A small-scale wind tunnel previously used for turbulent boundary layer experiments was modified for two sets of boundary layer transition studies. The first study concerns a laminar separation/turbulent reattachment. The pressure gradient and unit Reynolds number are the same as the fully turbulent flow of Spalart and Watmuff. Without the trip wire, a laminar layer asymptotes to a Falkner & Skan similarity solution in the FPG. Application of the APG causes the layer to separate and a highly turbulent and approximately 2D mean flow reattachment occurs downstream. In an effort to gain some physical insight into the flow processes a small impulsive disturbance was introduced at the C(sub p) minimum. The facility is totally automated and phase-averaged data are measured on a point-by-point basis using unprecedently large grids. The evolution of the disturbance has been tracked all the way into the reattachment region and beyond into the fully turbulent boundary layer. At first, the amplitude decays exponentially with streamwise distance in the APG region, where the layer remains attached, i.e. the layer is viscously stable. After separation, the rate of decay slows, and a point of minimum amplitude is reached where the contours of the wave packet exhibit dispersive characteristics. From this point, exponential growth of the amplitude of the disturbance is observed in the detached shear layer, i.e. the dominant instability mechanism is inviscid. A group of large-scale 3D vortex loops emerges in the vicinity of the reattachment. Remarkably, the second loop retains its identify far downstream in the turbulent boundary layer. The results provide a level of detail usually associated with CFD. Substantial modifications were made to the facility for the second study concerning disturbances generated by Suction Holes for laminar flow Control (LFC). The test section incorporates suction through interchangeable porous test surfaces. Detailed studies have been made using isolated

  13. Boundary layer transition studies

    Science.gov (United States)

    Watmuff, Jonathan H.

    1995-01-01

    A small-scale wind tunnel previously used for turbulent boundary layer experiments was modified for two sets of boundary layer transition studies. The first study concerns a laminar separation/turbulent reattachment. The pressure gradient and unit Reynolds number are the same as the fully turbulent flow of Spalart and Watmuff. Without the trip wire, a laminar layer asymptotes to a Falkner & Skan similarity solution in the FPG. Application of the APG causes the layer to separate and a highly turbulent and approximately 2D mean flow reattachment occurs downstream. In an effort to gain some physical insight into the flow processes a small impulsive disturbance was introduced at the C(sub p) minimum. The facility is totally automated and phase-averaged data are measured on a point-by-point basis using unprecedently large grids. The evolution of the disturbance has been tracked all the way into the reattachment region and beyond into the fully turbulent boundary layer. At first, the amplitude decays exponentially with streamwise distance in the APG region, where the layer remains attached, i.e. the layer is viscously stable. After separation, the rate of decay slows, and a point of minimum amplitude is reached where the contours of the wave packet exhibit dispersive characteristics. From this point, exponential growth of the amplitude of the disturbance is observed in the detached shear layer, i.e. the dominant instability mechanism is inviscid. A group of large-scale 3D vortex loops emerges in the vicinity of the reattachment. Remarkably, the second loop retains its identify far downstream in the turbulent boundary layer. The results provide a level of detail usually associated with CFD. Substantial modifications were made to the facility for the second study concerning disturbances generated by Suction Holes for laminar flow Control (LFC). The test section incorporates suction through interchangeable porous test surfaces. Detailed studies have been made using isolated

  14. Thermal processes and solidification kinetcs of evolution of the microstructure of tin-silver-copper solder alloys

    Science.gov (United States)

    Kinyanjui, Robert Kamau

    The adoption of Sn-Ag-Cu (SAC) Pb-free solders will affect electronic manufacturing processes and joint reliability for electronics packages. Since SAC solder has a higher melting temperature than eutectic Pb-Sn solder, higher processing temperatures will be required. The higher processing temperatures can potentially affect the microstructure of these Pb-free solder joints. We investigated the effect of thermal history on the evolution of the microstructure of Sn-xAg-yCu (0 ≤ x ≤ 4.0; 0 ≤ y ≤ 1.4, concentrations are in weight percent) solder alloys. This family of alloys falls within a class of Sn-rich Sn-Ag-Cu (SAC) alloys recommended by various international consortia for implementation in electronic manufacturing industry to replace the conventional PbSn solders. This investigation was divided into three parts: part one was an investigation of an optimum SAC alloy composition devoid of large (in length scales) intermetallic compounds (IMCs) after thermal treatment. The presence of large IMCs, with different mechanical characteristics from the bulk Sn, may compromise the mechanical integrity of the Pb-free solder interconnect. In part two of this study, we examined the growth morphology of Ag3Sn, Cu6Sn 5, and betaSn in the SAC alloys. In part three, an examination of the effect of sample size on undercooling was carried out. A Sn-Ag-Cu alloy of the composition: 96.5Sn-2.6Ag-0.9Cu (in weight percent) was found to exhibit no growth of large Ag3Sn, Cu6Sn 5 intermetallic compounds at cooling rates from 0.1 to 1°C/s. However, growth of large betaSn dendrites was observed. The crystallized Sn-Ag-Cu balls were found to contain only a few Sn grains. Also the solidification temperature of the 96.5Sn-2.6Ag-yCu (0 ≤ y ≤ 1.4) solder system was found to increase with Cu content. Further, this investigation established a strong correlation between Sn-Ag-Cu sample size and degree of undercooling for these Pb-free solder alloys. The degree of undercooling of Sn in

  15. Effect Mechanism of Rare Earth on the Microstructures of SnAgCu Solder Joints%稀土元素对SnAgCu焊点内部组织的影响机制

    Institute of Scientific and Technical Information of China (English)

    张亮; 韩继光; 郭永环; 何成文; 袁建民

    2012-01-01

    Due to the enhancement of environmental protection in our world, the research on lead-free solders has become the important role in electronic industry, the addition of rare earth can improve the properties of lead-free solders, based on the soldering testing of lead-free solders bearing rare earth Ce, the scanning electron microscope and energy dispersive X-ray spectroscopy technology are used to investigate the effect mechanism of rare earth Ce on the microstructure of SnAgCu solder joints systematically. The results indicated that CeSn3 with different morphologies appear in the solder matrix. The chemical affinity is utilized to describe the correlation between Ce and Sn, Ag, Cu elements, it can be demonstrated that the rare earth Ce had higher affinity for Sn in the SnAgCu system in theoretically. The adsorption effect of rare earth is investigated based on ULF principle, it can be used to explain the intermetallic compounds(IMCs) refinement of SnAgCu solder joints bearing rare earth Ce. With the microstructure analysis of SnAgCuCe solder joints, it is found that the order of IMCs particles sizes is CeSn3>Cu6Sn5>Ag3Sn, in the theory, it is confirmed that the Ag3Sn particles plays an important role in the strengthen of SnAgCu solder joints, which can provide the theory support for the research of lead-free solders.%随着人们环保意识的逐渐增强,新型无铅钎料的研究成为电子工业中的研究热点,而稀土元素的添加可以显著改善钎料的性能,基于含稀土Ce无铅钎料的钎焊试验,采用扫描电镜和能谱仪研究稀土元素Ce对SnAgCu焊点内部组织的影响机制.结果表明,稀土元素在SnAgCu焊点内部以CeSn3的形式存在,且稀土相形态各异.采用化学亲和力来表征稀土元素Ce与Sn、Ag、Cu之间的内在联系,从理论上证明Ce的“亲Sn性”.采用乌尔夫原理研究稀土元素的吸附现象,解释稀土元素Ce对SnAgCu焊点内部金属间化合物的细化作用.由SnAgCuCe焊

  16. Peeling Back the Layers

    Science.gov (United States)

    2004-01-01

    NASA's Mars Exploration Rover Spirit took this panoramic camera image of the rock target named 'Mazatzal' on sol 77 (March 22, 2004). It is a close-up look at the rock face and the targets that will be brushed and ground by the rock abrasion tool in upcoming sols. Mazatzal, like most rocks on Earth and Mars, has layers of material near its surface that provide clues about the history of the rock. Scientists believe that the top layer of Mazatzal is actually a coating of dust and possibly even salts. Under this light coating may be a more solid portion of the rock that has been chemically altered by weathering. Past this layer is the unaltered rock, which may give scientists the best information about how Mazatzal was formed. Because each layer reveals information about the formation and subsequent history of Mazatzal, it is important that scientists get a look at each of them. For this reason, they have developed a multi-part strategy to use the rock abrasion tool to systematically peel back Mazatzal's layers and analyze what's underneath with the rover's microscopic imager, and its Moessbauer and alpha particle X-ray spectrometers. The strategy began on sol 77 when scientists used the microscopic imager to get a closer look at targets on Mazatzal named 'New York,' 'Illinois' and 'Arizona.' These rock areas were targeted because they posed the best opportunity for successfully using the rock abrasion tool; Arizona also allowed for a close-up look at a range of tones. On sol 78, Spirit's rock abrasion tool will do a light brushing on the Illinois target to preserve some of the surface layers. Then, a brushing of the New York target should remove the top coating of any dust and salts and perhaps reveal the chemically altered rock underneath. Finally, on sol 79, the rock abrasion tool will be commanded to grind into the New York target, which will give scientists the best chance of observing Mazatzal's interior. The Mazatzal targets were named after the home states of

  17. Crack layer theory

    Science.gov (United States)

    Chudnovsky, A.

    1984-01-01

    A damage parameter is introduced in addition to conventional parameters of continuum mechanics and consider a crack surrounded by an array of microdefects within the continuum mechanics framework. A system consisting of the main crack and surrounding damage is called crack layer (CL). Crack layer propagation is an irreversible process. The general framework of the thermodynamics of irreversible processes are employed to identify the driving forces (causes) and to derive the constitutive equation of CL propagation, that is, the relationship between the rates of the crack growth and damage dissemination from one side and the conjugated thermodynamic forces from another. The proposed law of CL propagation is in good agreement with the experimental data on fatigue CL propagation in various materials. The theory also elaborates material toughness characterization.

  18. Layered bismuth vanadate ferroelectrics

    Energy Technology Data Exchange (ETDEWEB)

    Osipyan, V.G.; Savchenko, L.M.; Elbakyan, V.L.; Avakyan, P.B.

    1987-08-01

    The authors synthesize new layered bismuth vanadate ferroelectrics. The x-ray diffraction characteristics of Bi/sub 2/VO/sub 5.5/ are shown. Thermal expansion of ceramics with various compositions are presented, as are the temperature dependences of the dielectric constant of the ceramic with various compositions. Unit-cell parameters, Curie temperature, electrical conductivity and the dielectric characteristics of the compositions studied are shown.

  19. Boundary-layer theory

    CERN Document Server

    Schlichting (Deceased), Hermann

    2017-01-01

    This new edition of the near-legendary textbook by Schlichting and revised by Gersten presents a comprehensive overview of boundary-layer theory and its application to all areas of fluid mechanics, with particular emphasis on the flow past bodies (e.g. aircraft aerodynamics). The new edition features an updated reference list and over 100 additional changes throughout the book, reflecting the latest advances on the subject.

  20. CHALCOGENIDE MISFIT LAYER COMPOUNDS

    NARCIS (Netherlands)

    ROUXEL, J; MEERSCHAUT, A; WIEGERS, GA

    1995-01-01

    Misfit layer chalcogenides (MX)(1+x)(TX(2))(m) (M=Sn, Pb, Sb, Bi, rare earth; T=Ti, V, Cr, Nb, Ta; X=S, Se; 0.08

  1. Physical Layer Network Coding

    DEFF Research Database (Denmark)

    Fukui, Hironori; Yomo, Hironori; Popovski, Petar

    2013-01-01

    Physical layer network coding (PLNC) has the potential to improve throughput of multi-hop networks. However, most of the works are focused on the simple, three-node model with two-way relaying, not taking into account the fact that there can be other neighboring nodes that can cause/receive inter......Physical layer network coding (PLNC) has the potential to improve throughput of multi-hop networks. However, most of the works are focused on the simple, three-node model with two-way relaying, not taking into account the fact that there can be other neighboring nodes that can cause....../receive interference. The way to deal with this problem in distributed wireless networks is usage of MAC-layer mechanisms that make a spatial reservation of the shared wireless medium, similar to the well-known RTS/CTS in IEEE 802.11 wireless networks. In this paper, we investigate two-way relaying in presence...

  2. Multifunctional layered magnetic composites

    Directory of Open Access Journals (Sweden)

    Maria Siglreitmeier

    2015-01-01

    Full Text Available A fabrication method of a multifunctional hybrid material is achieved by using the insoluble organic nacre matrix of the Haliotis laevigata shell infiltrated with gelatin as a confined reaction environment. Inside this organic scaffold magnetite nanoparticles (MNPs are synthesized. The amount of MNPs can be controlled through the synthesis protocol therefore mineral loadings starting from 15 wt % up to 65 wt % can be realized. The demineralized organic nacre matrix is characterized by small-angle and very-small-angle neutron scattering (SANS and VSANS showing an unchanged organic matrix structure after demineralization compared to the original mineralized nacre reference. Light microscopy and confocal laser scanning microscopy studies of stained samples show the presence of insoluble proteins at the chitin surface but not between the chitin layers. Successful and homogeneous gelatin infiltration in between the chitin layers can be shown. The hybrid material is characterized by TEM and shows a layered structure filled with MNPs with a size of around 10 nm. Magnetic analysis of the material demonstrates superparamagnetic behavior as characteristic for the particle size. Simulation studies show the potential of collagen and chitin to act as nucleators, where there is a slight preference of chitin over collagen as a nucleator for magnetite. Colloidal-probe AFM measurements demonstrate that introduction of a ferrogel into the chitin matrix leads to a certain increase in the stiffness of the composite material.

  3. Modern Thin-Layer Chromatography.

    Science.gov (United States)

    Poole, Colin F.; Poole, Salwa K.

    1989-01-01

    Some of the important modern developments of thin-layer chromatography are introduced. Discussed are the theory and instrumentation of thin-layer chromatography including multidimensional and multimodal techniques. Lists 53 references. (CW)

  4. Modern Thin-Layer Chromatography.

    Science.gov (United States)

    Poole, Colin F.; Poole, Salwa K.

    1989-01-01

    Some of the important modern developments of thin-layer chromatography are introduced. Discussed are the theory and instrumentation of thin-layer chromatography including multidimensional and multimodal techniques. Lists 53 references. (CW)

  5. Diversity in S-layers.

    Science.gov (United States)

    Zhu, Chaohua; Guo, Gang; Ma, Qiqi; Zhang, Fengjuan; Ma, Funing; Liu, Jianping; Xiao, Dao; Yang, Xiaolin; Sun, Ming

    2017-01-01

    Surface layers, referred simply as S-layers, are the two-dimensional crystalline arrays of protein or glycoprotein subunits on cell surface. They are one of the most common outermost envelope components observed in prokaryotic organisms (Archaea and Bacteria). Over the past decades, S-layers have become an issue of increasing interest due to their ubiquitousness, special features and functions. Substantial work in this field provides evidences of an enormous diversity in S-layers. This paper reviews and illustrates the diversity from several different aspects, involving the S-layer-carrying strains, the structure of S-layers, the S-layer proteins and genes, as well as the functions of S-layers.

  6. Elemental and Chemical Mapping of High Capacity Intermetallic Li-ion Anodes with Transmission X-ray Microscopy

    Science.gov (United States)

    Ausderau, Logan J.; Gonzalez Malabet, Hernando J.; Buckley, Joseph R.; De Andrade, Vincent; Liu, Yijin; Nelson, George J.

    2017-09-01

    X-ray nanotomography has been applied toward the three-dimensional (3D) imaging of a Li-ion battery alloy anode material (Cu6Sn5), and subsequent segmentation and analysis has been performed to distinguish the alloy material from its constituent components. Follow-on x-ray absorption near edge structure imaging was performed yielding absorption spectra for Cu, Cu6Sn5, and Li2CuSn. Analyses based on these spectra were performed on two-dimensional (2D) images of samples from cycled electrodes to assess chemical composition in Cu-containing phases. The capability to distinguish the different materials within mixed samples suggests that microstructure and composition changes resulting from lithiation and delithiation in Cu6Sn5 may be observed and better understood with 3D x-ray imaging methods. These methods are expected to be applicable to other intermetallic tin alloy electrodes.

  7. Protecting the ozone layer.

    Science.gov (United States)

    Munasinghe, M; King, K

    1992-06-01

    Stratospheric ozone layer depletion has been recognized as a problem by the Vienna Convention for the Protection of the Ozone Layer and the 1987 Montreal Protocol (MP). The ozone layer shields the earth from harmful ultraviolet radiation (UV-B), which is more pronounced at the poles and around the equator. Industrialized countries have contributed significantly to the problem by releasing chlorofluorocarbons (CFCs) and halons into the atmosphere. The effect of these chemicals, which were known for their inertness, nonflammability, and nontoxicity, was discovered in 1874. Action to deal with the effects of CFCs and halons was initiated in 1985 in a 49-nation UN meeting. 21 nations signed a protocol limiting ozone depleting substances (ODS): CFCs and halons. Schedules were set based on each country's use in 1986; the target phaseout was set for the year 2000. The MP restricts trade in ODSs and weights the impact of substances to reflect the extent of damage; i.e., halons are 10 times more damaging than CFCs. ODS requirements for developing countries were eased to accommodate scarce resources and the small fraction of ODS emissions. An Interim Multilateral Fund under the Montreal Protocol (IMFMP) was established to provide loans to finance the costs to developing countries in meeting global environmental requirements. The IMFMP is administered by the World Bank, the UN Environmental Program, and the UN Development Program. Financing is available to eligible countries who use .3 kg of ODS/person/year. Rapid phaseout in developed countries has occurred due to strong support from industry and a lower than expected cost. Although there are clear advantages to rapid phaseout, there were no incentives included in the MP for rapid phaseout. Some of the difficulties occur because the schedules set minimum targets at the lowest possible cost. Also, costs cannot be minimized by a country-specific and ODS-specific process. The ways to improve implementation in scheduling and

  8. Cooperating systems: Layered MAS

    Science.gov (United States)

    Rochowiak, Daniel

    1990-01-01

    Distributed intelligent systems can be distinguished by the models that they use. The model developed focuses on layered multiagent system conceived of as a bureaucracy in which a distributed data base serves as a central means of communication. The various generic bureaus of such a system is described and a basic vocabulary for such systems is presented. In presenting the bureaus and vocabularies, special attention is given to the sorts of reasonings that are appropriate. A bureaucratic model has a hierarchy of master system and work group that organizes E agents and B agents. The master system provides the administrative services and support facilities for the work groups.

  9. Basis reduction for layered lattices

    NARCIS (Netherlands)

    Torreão Dassen, Erwin

    2011-01-01

    We develop the theory of layered Euclidean spaces and layered lattices. We present algorithms to compute both Gram-Schmidt and reduced bases in this generalized setting. A layered lattice can be seen as lattices where certain directions have infinite weight. It can also be interpre

  10. The Boundary Layer Radiometer

    Science.gov (United States)

    Irshad, Ranah; Bowles, N. E.; Calcutt, S. B.; Hurley, J.

    2010-10-01

    The Boundary Layer Radiometer is a small, low mass (<1kg) radiometer with only a single moving part - a scan/calibration mirror. The instrument consists of a three mirror telescope system incorporating an intermediate focus for use with miniature infrared and visible filters. It also has an integrated low power blackbody calibration target to provide long-term calibration stability The instrument may be used as an upward looking boundary layer radiometer for both the terrestrial and Martian atmospheres with appropriate filters for the mid-infrared carbon dioxide band, as well as a visible channel for the detection of aerosol components such as dust. The scan mirror may be used to step through different positions from the local horizon to the zenith, allowing the vertical temperature profile of the atmosphere to be retrieved. The radiometer uses miniature infrared filter assemblies developed for previous space-based instruments by Oxford, Cardiff and Reading Universities. The intermediate focus allows for the use of upstream blocking filters and baffles, which not only simplifies the design of the filters and focal plane assembly, but also reduces the risk of problems due to stray light. Combined with the calibration target this means it has significant advantages over previous generations of small radiometers.

  11. Thin layer chromatography.

    Science.gov (United States)

    Santiago, Marina; Strobel, Scott

    2013-01-01

    In many experiments, it is important to be able to separate a mixture into its chemical components in order to isolate one compound or to assess the purity of the mixture. Thin layer chromatography (TLC) is one of the easiest and most versatile methods of doing this because of its low cost, simplicity, quick development time, high sensitivity, and good reproducibility. TLC is used by many industries and fields of research, including pharmaceutical production, clinical analysis, industrial chemistry, environmental toxicology, food chemistry, water, inorganic, and pesticide analysis, dye purity, cosmetics, plant materials, and herbal analysis. In its simplest form, glass plates are coated with a uniform layer of silica gel (SiO2). The dissolved sample is placed on the plate, and the plate is inserted into a screw-top jar containing the developing solvent and a piece of filter paper. When the solvent has risen to near the top of the plate, the plate is removed, dried, and visualized using UV light. Variations on this protocol are used for different purposes, including pretreating the sample, changing the sorbent, plate material, the solvent system, the development techniques, and method of detection and visualization or by coupling TLC to other techniques. © 2013 Elsevier Inc. All rights reserved.

  12. Multiresonant layered plasmonic films

    Energy Technology Data Exchange (ETDEWEB)

    DeVetter, Brent M. [Pacific Northwest National Laboratory, Richland, Washington, United States; Bernacki, Bruce E. [Pacific Northwest National Laboratory, Richland, Washington, United States; Bennett, Wendy D. [Pacific Northwest National Laboratory, Richland, Washington, United States; Schemer-Kohrn, Alan [Pacific Northwest National Laboratory, Richland, Washington, United States; Alvine, Kyle J. [Pacific Northwest National Laboratory, Richland, Washington, United States

    2017-01-01

    Multi-resonant nanoplasmonic films have numerous applications in areas such as nonlinear optics, sensing, and tamper indication. While techniques such as focused ion beam milling and electron beam lithography can produce high-quality multi-resonant films, these techniques are expensive, serial processes that are difficult to scale at the manufacturing level. Here, we present the fabrication of multi-resonant nanoplasmonic films using a layered stacking technique. Periodically-spaced gold nanocup substrates were fabricated using self-assembled polystyrene nanospheres followed by oxygen plasma etching and metal deposition via magnetron sputter coating. By adjusting etch parameters and initial nanosphere size, it was possible to achieve an optical response ranging from the visible to the near-infrared. Singly resonant, flexible films were first made by performing peel-off using an adhesive-coated polyolefin film. Through stacking layers of the nanofilm, we demonstrate fabrication of multi-resonant films at a fraction of the cost and effort as compared to top-down lithographic techniques.

  13. Layered kagome spin ice

    Science.gov (United States)

    Hamp, James; Dutton, Sian; Mourigal, Martin; Mukherjee, Paromita; Paddison, Joseph; Ong, Harapan; Castelnovo, Claudio

    Spin ice materials provide a rare instance of emergent gauge symmetry and fractionalisation in three dimensions: the effective degrees of freedom of the system are emergent magnetic monopoles, and the extensively many `ice rule' ground states are those devoid of monopole excitations. Two-dimensional (kagome) analogues of spin ice have also been shown to display a similarly rich behaviour. In kagome ice however the ground-state `ice rule' condition implies the presence everywhere of magnetic charges. As temperature is lowered, an Ising transition occurs to a charge-ordered state, which can be mapped to a dimer covering of the dual honeycomb lattice. A second transition, of Kosterlitz-Thouless or three-state Potts type, occurs to a spin-ordered state at yet lower temperatures, due to small residual energy differences between charge-ordered states. Inspired by recent experimental capabilities in growing spin ice samples with selective (layered) substitution of non-magnetic ions, in this work we investigate the fate of the two ordering transitions when individual kagome layers are brought together to form a three-dimensional pyrochlore structure coupled by long range dipolar interactions. We also consider the response to substitutional disorder and applied magnetic fields.

  14. Analysis of turbulent boundary layers

    CERN Document Server

    Cebeci, Tuncer

    1974-01-01

    Analysis of Turbulent Boundary Layers focuses on turbulent flows meeting the requirements for the boundary-layer or thin-shear-layer approximations. Its approach is devising relatively fundamental, and often subtle, empirical engineering correlations, which are then introduced into various forms of describing equations for final solution. After introducing the topic on turbulence, the book examines the conservation equations for compressible turbulent flows, boundary-layer equations, and general behavior of turbulent boundary layers. The latter chapters describe the CS method for calculati

  15. The Adobe Photoshop layers book

    CERN Document Server

    Lynch, Richard

    2011-01-01

    Layers are the building blocks for working in Photoshop. With the correct use of the Layers Tool, you can edit individual components of your images nondestructively to ensure that your end result is a combination of the best parts of your work. Despite how important it is for successful Photoshop work, the Layers Tool is one of the most often misused and misunderstood features within this powerful software program. This book will show you absolutely everything you need to know to work with layers, including how to use masks, blending, modes and layer management. You'll learn professional tech

  16. Metal deposition using seed layers

    Science.gov (United States)

    Feng, Hsein-Ping; Chen, Gang; Bo, Yu; Ren, Zhifeng; Chen, Shuo; Poudel, Bed

    2013-11-12

    Methods of forming a conductive metal layers on substrates are disclosed which employ a seed layer to enhance bonding, especially to smooth, low-roughness or hydrophobic substrates. In one aspect of the invention, the seed layer can be formed by applying nanoparticles onto a surface of the substrate; and the metallization is achieved by electroplating an electrically conducting metal onto the seed layer, whereby the nanoparticles serve as nucleation sites for metal deposition. In another approach, the seed layer can be formed by a self-assembling linker material, such as a sulfur-containing silane material.

  17. The multiple layer solar collector

    Science.gov (United States)

    Kenna, J. P.

    1983-01-01

    An analytical model is developed for obtaining numerical solutions for differential equations describing the performance of separate layers in a multiple layer solar collector. The configurations comprises heat transfer fluid entering at the top of the collector and travelling down through several layers. A black absorber plate prevents reemission of thermal radiation. The overall performance is shown to depend on the number of layers, the heat transfer coefficient across each layer, and the absorption properties of the working fluid. It is found that the multiple layer system has a performance inferior to that of flat plate selective surface collectors. Air gaps insulating adjacent layers do not raise the efficiency enough to overcome the relative deficiency.

  18. Aeolian transport layer.

    Science.gov (United States)

    Almeida, Murilo P; Andrade, José S; Herrmann, Hans J

    2006-01-13

    We investigate the airborne transport of particles on a granular surface by the saltation mechanism through numerical simulation of particle motion coupled with turbulent flow. We determine the saturated flux q(s) and show that its behavior is consistent with classical empirical relations obtained from wind tunnel measurements. Our results also allow one to propose and explain a new relation valid for small fluxes, namely, q(s) = a(u*-u(t))alpha, where u* and u(t) are the shear and threshold velocities of the wind, respectively, and the scaling exponent is alpha approximately 2. We obtain an expression for the velocity profile of the wind distorted by the particle motion due to the feedback and discover a novel dynamical scaling relation. We also find a new expression for the dependence of the height of the saltation layer as a function of the wind velocity.

  19. The layers of subtitling

    Directory of Open Access Journals (Sweden)

    Elena Di Giovanni

    2016-12-01

    Full Text Available The study of subtitling, although widely practiced over the past 20 years, has generally been confined to comparative studies focusing on the product of subtitle translation, with little or no consideration of the conditions of creation and reception. Focusing on the process of subtitle production, occasional studies have touched upon the cognitive processes accompanying it, but no study so far has related these processes, and the resulting products, to various degrees of translators’ competence. This is precisely what this essay does, focusing on the different layers of subtitle translation provided for two different films and in two different contexts. By analysing the first and second versions of subtitle translations, we shall reflect on the acquisition, and application, of different subtitling competences.

  20. Transparent layer constancy.

    Science.gov (United States)

    Faul, Franz; Ekroll, Vebjørn

    2012-11-14

    In transparency perception the visual system assigns transmission-related attributes to transparent layers. Based on a filter model of perceptual transparency we investigate to what extent these attributes remain constant across changes of background and illumination. On a computational level, we used computer simulations to test how constant the parameters of the filter model remain under realistic changes in background reflectances and illumination and found almost complete constancy. This contrasts with systematic deviations from constancy found in cross-context matches of transparent filters. We show that these deviations are of a very regular nature and can be understood as a compromise between a proximal match of the mean stimulus color and complete constancy as predicted by the filter model.

  1. Wireless physical layer security

    Science.gov (United States)

    Poor, H. Vincent; Schaefer, Rafael F.

    2017-01-01

    Security in wireless networks has traditionally been considered to be an issue to be addressed separately from the physical radio transmission aspects of wireless systems. However, with the emergence of new networking architectures that are not amenable to traditional methods of secure communication such as data encryption, there has been an increase in interest in the potential of the physical properties of the radio channel itself to provide communications security. Information theory provides a natural framework for the study of this issue, and there has been considerable recent research devoted to using this framework to develop a greater understanding of the fundamental ability of the so-called physical layer to provide security in wireless networks. Moreover, this approach is also suggestive in many cases of coding techniques that can approach fundamental limits in practice and of techniques for other security tasks such as authentication. This paper provides an overview of these developments.

  2. Templated quasicrystalline molecular layers

    Science.gov (United States)

    Smerdon, Joe; Young, Kirsty; Lowe, Michael; Hars, Sanger; Yadav, Thakur; Hesp, David; Dhanak, Vinod; Tsai, An-Pang; Sharma, Hem Raj; McGrath, Ronan

    2014-03-01

    Quasicrystals are materials with long range ordering but no periodicity. We report scanning tunneling microscopy (STM) observations of quasicrystalline molecular layers on five-fold quasicrystal surfaces. The molecules adopt positions and orientations on the surface consistent with the quasicrystalline ordering of the substrate. Carbon-60 adsorbs atop sufficiently-separated Fe atoms on icosahedral Al-Cu-Fe to form a unique quasicrystalline lattice whereas further C60 molecules decorate remaining surface Fe atoms in a quasi-degenerate fashion. Pentacene (Pn) adsorbs at tenfold-symmetric points around surface-bisected rhombic triacontahedral clusters in icosahedral Ag-In-Yb. These systems constitute the first demonstrations of quasicrystalline molecular ordering on a template. EPSRC EP/D05253X/1, EP/D071828/1, UK BIS.

  3. Ferroelectrics based absorbing layers

    Science.gov (United States)

    Hao, Jianping; Sadaune, Véronique; Burgnies, Ludovic; Lippens, Didier

    2014-07-01

    We show that ferroelectrics-based periodic structure made of BaSrTiO3 (BST) cubes, arrayed onto a metal plate with a thin dielectric spacer film exhibit a dramatic enhancement of absorbance with value close to unity. The enhancement is found around the Mie magnetic resonance of the Ferroelectrics cubes with the backside metal layer stopping any transmitted waves. It also involves quasi-perfect impedance matching resulting in reflection suppression via simultaneous magnetic and electrical activities. In addition, it was shown numerically the existence of a periodicity optimum, which is explained from surface waves analysis along with trade-off between the resonance damping and the intrinsic loss of ferroelectrics cubes. An experimental verification in a hollow waveguide configuration with a good comparison with full-wave numerical modelling is at last reported by measuring the scattering parameters of single and dual BST cubes schemes pointing out coupling effects for densely packed structures.

  4. Ozone Layer Observations

    Science.gov (United States)

    McPeters, Richard; Bhartia, P. K. (Technical Monitor)

    2002-01-01

    The US National Aeronautics and Space Administration (NASA) has been monitoring the ozone layer from space using optical remote sensing techniques since 1970. With concern over catalytic destruction of ozone (mid-1970s) and the development of the Antarctic ozone hole (mid-1980s), long term ozone monitoring has become the primary focus of NASA's series of ozone measuring instruments. A series of TOMS (Total Ozone Mapping Spectrometer) and SBUV (Solar Backscatter Ultraviolet) instruments has produced a nearly continuous record of global ozone from 1979 to the present. These instruments infer ozone by measuring sunlight backscattered from the atmosphere in the ultraviolet through differential absorption. These measurements have documented a 15 Dobson Unit drop in global average ozone since 1980, and the declines in ozone in the antarctic each October have been far more dramatic. Instruments that measure the ozone vertical distribution, the SBUV and SAGE (Stratospheric Aerosol and Gas Experiment) instruments for example, show that the largest changes are occurring in the lower stratosphere and upper troposphere. The goal of ozone measurement in the next decades will be to document the predicted recovery of the ozone layer as CFC (chlorofluorocarbon) levels decline. This will require a continuation of global measurements of total column ozone on a global basis, but using data from successor instruments to TOMS. Hyperspectral instruments capable of measuring in the UV will be needed for this purpose. Establishing the relative roles of chemistry and dynamics will require instruments to measure ozone in the troposphere and in the stratosphere with good vertical resolution. Instruments that can measure other chemicals important to ozone formation and destruction will also be needed.

  5. The Plasmasphere Boundary Layer

    Directory of Open Access Journals (Sweden)

    D. L. Carpenter

    2004-12-01

    Full Text Available As an inner magnetospheric phenomenon the plasmapause region is of interest for a number of reasons, one being the occurrence there of geophysically important interactions between the plasmas of the hot plasma sheet and of the cool plasmasphere. There is a need for a conceptual framework within which to examine and discuss these interactions and their consequences, and we therefore suggest that the plasmapause region be called the Plasmasphere Boundary Layer, or PBL. Such a term has been slow to emerge because of the complexity and variability of the plasma populations that can exist near the plasmapause and because of the variety of criteria used to identify the plasmapause in experimental data. Furthermore, and quite importantly in our view, a substantial obstacle to the consideration of the plasmapause region as a boundary layer has been the longstanding tendency of textbooks on space physics to limit introductory material on the plasmapause phenomenon to zeroth order descriptions in terms of ideal MHD theory, thus implying that the plasmasphere is relatively well understood. A textbook may introduce the concept of shielding of the inner magnetosphere from perturbing convection electric fields, but attention is not usually paid to the variety of physical processes reported to occur in the PBL, such as heating, instabilities, and fast longitudinal flows, processes which must play roles in plasmasphere dynamics in concert with the flow regimes associated with the major dynamo sources of electric fields. We believe that through the use of the PBL concept in future textbook discussions of the plasmasphere and in scientific communications, much progress can be made on longstanding questions about the physics involved in the formation of the plasmapause and in the cycles of erosion and recovery of the plasmasphere.

    Key words. Magnetospheric physics (plasmasphere; plasma convection; MHD waves and instabilities

  6. Effects of Ni{sub 3}Sn{sub 4} and (Cu,Ni){sub 6}Sn{sub 5} intermetallic layers on cross-interaction between Pd and Ni in solder joints

    Energy Technology Data Exchange (ETDEWEB)

    Baek, Yong-Ho [Department of Materials Science and Engineering, Korea University, Seoul 136-713 (Korea, Republic of); Division of Advanced Circuit Interconnect, Samsung Electro-Mechanics Co., Ltd., Suwon 443-743 (Korea, Republic of); Chung, Bo-Mook [Department of Materials Science and Engineering, Korea University, Seoul 136-713 (Korea, Republic of); Department of Research and Development, KPM TECH, Ansan 425-090 (Korea, Republic of); Choi, Young-Sik [Division of Advanced Circuit Interconnect, Samsung Electro-Mechanics Co., Ltd., Suwon 443-743 (Korea, Republic of); Choi, Jaeho [Department of Advanced Metal and Materials Engineering, Gangneung-Wonju National University, Gangneung 210-702 (Korea, Republic of); Huh, Joo-Youl, E-mail: jyhuh@korea.ac.kr [Department of Materials Science and Engineering, Korea University, Seoul 136-713 (Korea, Republic of)

    2013-12-05

    Highlights: •Ni{sub 3}Sn{sub 4} acts as a source of Ni atoms, leading to a strong cross-interaction with Pd. •(Cu,Ni){sub 6}Sn{sub 5} is an effective Ni diffusion barrier, inhibiting Pd resettlement. •Dissolution kinetics of (Pd,Ni)Sn{sub 4} was interpreted based on the Sn–Ni–Pd isotherm. •Cu addition to solder alleviates the (Pd,Ni)Sn{sub 4}-related risk of reliability deterioration. -- Abstract: We examined the effects of layers of intermetallic compound (IMC) Ni{sub 3}Sn{sub 4} and (Cu,Ni){sub 6}Sn{sub 5} formed at the solder/Ni interface, on the cross-interactions between Pd and Ni during solid-state aging and reflow soldering. Two types of diffusion couples, Pd/Sn/Ni and Pd/Sn–Cu/Ni, were aged at 150 °C to study the solid-state interactions. In contrast to the Pd/Sn/Ni couples in which a Ni{sub 3}Sn{sub 4} layer formed at the Ni interface, the Pd/Sn–Cu/Ni couple where a (Cu,Ni){sub 6}Sn{sub 5} layer formed at the Ni interface exhibited no significant interaction between Pd and Ni. The (Cu,Ni){sub 6}Sn{sub 5} layer acted as an effective barrier against Ni diffusion and thus inhibited the resettlement of (Pd,Ni)Sn{sub 4} onto the Ni interface. For the interaction during reflow, Sn–3.5Ag and Sn–3.0Ag–0.5Cu solder balls were isothermally reflowed on an electroless Ni(P)/electroless Pd/immersion Au (ENEPIG) surface finish at 250 °C, and the dissolution kinetics of the (Pd,Ni)Sn{sub 4} particles converted from the 0.2-μm-thick Pd-finish layer were examined. The spalled (Pd,Ni)Sn{sub 4} particles very quickly dissolved into the molten solder when the IMC layer formed on the Ni substrate was (Cu,Ni){sub 6}Sn{sub 5} rather than Ni{sub 3}Sn{sub 4}. The dependence of the dissolution kinetics of the spalled (Pd,Ni)Sn{sub 4} particles on the IMC layers was rationalized on the basis of a Sn–Ni–Pd isotherm at 250 °C. The present study suggests that the formation of a dense (Cu,Ni){sub 6}Sn{sub 5} layer at the solder/Ni interface can effectively

  7. Processes for multi-layer devices utilizing layer transfer

    Energy Technology Data Exchange (ETDEWEB)

    Nielson, Gregory N; Sanchez, Carlos Anthony; Tauke-Pedretti, Anna; Kim, Bongsang; Cederberg, Jeffrey; Okandan, Murat; Cruz-Campa, Jose Luis; Resnick, Paul J

    2015-02-03

    A method includes forming a release layer over a donor substrate. A plurality of devices made of a first semiconductor material are formed over the release layer. A first dielectric layer is formed over the plurality of devices such that all exposed surfaces of the plurality of devices are covered by the first dielectric layer. The plurality of devices are chemically attached to a receiving device made of a second semiconductor material different than the first semiconductor material, the receiving device having a receiving substrate attached to a surface of the receiving device opposite the plurality of devices. The release layer is etched to release the donor substrate from the plurality of devices. A second dielectric layer is applied over the plurality of devices and the receiving device to mechanically attach the plurality of devices to the receiving device.

  8. Processes for multi-layer devices utilizing layer transfer

    Science.gov (United States)

    Nielson, Gregory N; Sanchez, Carlos Anthony; Tauke-Pedretti, Anna; Kim, Bongsang; Cederberg, Jeffrey; Okandan, Murat; Cruz-Campa, Jose Luis; Resnick, Paul J

    2015-02-03

    A method includes forming a release layer over a donor substrate. A plurality of devices made of a first semiconductor material are formed over the release layer. A first dielectric layer is formed over the plurality of devices such that all exposed surfaces of the plurality of devices are covered by the first dielectric layer. The plurality of devices are chemically attached to a receiving device made of a second semiconductor material different than the first semiconductor material, the receiving device having a receiving substrate attached to a surface of the receiving device opposite the plurality of devices. The release layer is etched to release the donor substrate from the plurality of devices. A second dielectric layer is applied over the plurality of devices and the receiving device to mechanically attach the plurality of devices to the receiving device.

  9. Aging Characteristics of Sn-Ag Eutectic Solder Alloy with the Addition of Cu, In, and Mn

    Science.gov (United States)

    Ghosh, M.; Kar, Abhijit; Das, S. K.; Ray, A. K.

    2009-10-01

    In the present investigation, three types of solder alloy, i.e., Sn-Ag-Cu, Sn-Ag-In, and Sn-Ag-Cu-Mn, have been prepared and joined with Cu substrate. In the reflowed condition, the joint interface is decorated with Cu6Sn5 intermetallic in all cases. During aging at 100 °C for 50 to 200 hours, Cu3Sn formation took place in the diffusion zone of the Sn-Ag-Cu and Sn-Ag-In vs Cu assembly, which was not observed for the Sn-Ag-Cu-Mn vs Cu joint. Aging also leads to enhancement in the width of reaction layers; however, the growth is sluggish (~134 KJ/mol) for the Sn-Ag-Cu-Mn vs Cu transition joint. In the reflowed condition, the highest shear strength is obtained for the Sn-Ag-Cu-Mn vs Cu joint. Increment in aging time results in decrement in shear strength of the assemblies; yet small reduction is observed for the Sn-Ag-Cu-Mn vs Cu joint. The presence of Mn in the solder alloy is responsible for the difference in microstructure of the Sn-Ag-Cu-Mn solder alloy vs Cu assembly in the reflowed condition, which in turn influences the microstructure of the same after aging with respect to others.

  10. Microstructure and mechanical behavior of novel rare earth-containing Pb-Free solders

    Science.gov (United States)

    Dudek, M. A.; Sidhu, R. S.; Chawla, N.; Renavikar, M.

    2006-12-01

    Sn-rich solders have been shown to have superior mechanical properties when compared to the Pb-Sn system. Much work remains to be done in developing these materials for electronic packaging. In this paper, we report on the microstructure and mechanical properties of La-containing Sn-3.9Ag-0.7Cu alloys. The addition of small amounts of La (up to 0.5 wt.%) to Sn-Ag-Cu refined the microstructure by decreasing the length and spacing of the Sn dendrites and decreased the thickness of the Cu6Sn5 intermetallic layer at the Cu/solder interface. As a result of the change in the microstructure, Sn-Ag-Cu alloys with La additions exhibited a small decrease in ultimate shear strength but significantly higher elongations compared with Sn-Ag-Cu. The influence of LaSn3 intermetallics on microstructural refinement and damage evolution in these novel solders is discussed. Our results have profound implications for improving the mechanical shock resistance of Pb-free solders.

  11. Morphology and Shear Strength of Lead-Free Solder Joints with Sn3.0Ag0.5Cu Solder Paste Reinforced with Ceramic Nanoparticles

    Science.gov (United States)

    Yakymovych, A.; Plevachuk, Yu.; Švec, P.; Švec, P.; Janičkovič, D.; Šebo, P.; Beronská, N.; Roshanghias, A.; Ipser, H.

    2016-12-01

    To date, additions of different oxide nanoparticles is one of the most widespread procedures to improve the mechanical properties of metals and metal alloys. This research deals with the effect of minor ceramic nanoparticle additions (SiO2, TiO2 and ZrO2) on the microstructure and mechanical properties of Cu/solder/Cu joints. The reinforced Sn3.0Ag0.5Cu (SAC305) solder alloy with 0.5 wt.% and 1.0 wt.% of ceramic nanoparticles was prepared through mechanically stirring. The microstructure of as-solidified Cu/solder/Cu joints was studied using scanning electron microscopy. The additions of ceramic nanoparticles suppressed the growth of the intermetallic compound layer Cu6Sn5 at the interface solder/Cu and improved the microstructure of the joints. Furthermore, measurements of mechanical properties showed improved shear strength of Cu/composite solder/Cu joints compared to joints with unreinforced solder. This fact related to all investigated ceramic nanoinclusions and should be attributed to the adsorption of nanoparticles on the grain surface during solidification. However, this effect is less pronounced on increasing the nanoinclusion content from 0.5 wt.% to 1.0 wt.% due to agglomeration of nanoparticles. Moreover, a comparison analysis showed that the most beneficial influence was obtained by minor additions of SiO2 nanoparticles into the SAC305 solder alloy.

  12. Inter-layer synchronization in multiplex networks of identical layers

    Energy Technology Data Exchange (ETDEWEB)

    Sevilla-Escoboza, R. [Centro Universitario de los Lagos, Universidad de Guadalajara, Jalisco 47460 (Mexico); Sendiña-Nadal, I.; Leyva, I.; Buldú, J. M. [Complex Systems Group & GISC, Universidad Rey Juan Carlos, 28933 Móstoles, Madrid (Spain); Center for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid (Spain); Gutiérrez, R. [School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD (United Kingdom); Boccaletti, S. [CNR-Institute of Complex Systems, Via Madonna del Piano, 10, 50019 Sesto Fiorentino, Florence (Italy); The Italian Embassy in Israel, 25 Hamered st., 68125 Tel Aviv (Israel)

    2016-06-15

    Inter-layer synchronization is a distinctive process of multiplex networks whereby each node in a given layer evolves synchronously with all its replicas in other layers, irrespective of whether or not it is synchronized with the other units of the same layer. We analytically derive the necessary conditions for the existence and stability of such a state, and verify numerically the analytical predictions in several cases where such a state emerges. We further inspect its robustness against a progressive de-multiplexing of the network, and provide experimental evidence by means of multiplexes of nonlinear electronic circuits affected by intrinsic noise and parameter mismatch.

  13. Neocortical layer 6, a review

    Directory of Open Access Journals (Sweden)

    Alex M Thomson

    2010-03-01

    Full Text Available This review attempts to summarise some of the major areas of neocortical research as it pertains to layer 6. After a brief summary of the development of this intriguing layer, the major pyramidal cell classes to be found in layer 6 are described and compared. The connections made and received by these different classes of neurones are then discussed and the possible functions of these connections, with particular reference to the shaping of responses in visual cortex and thalamus. Inhibition in layer 6 is discussed where appropriate, but not in great detail. Many types of interneurones are to be found in each cortical layer and layer 6 is no exception, but the functions of each type remain to be elucidated.

  14. Nanostructure Neutron Converter Layer Development

    Science.gov (United States)

    Park, Cheol (Inventor); Sauti, Godfrey (Inventor); Kang, Jin Ho (Inventor); Lowther, Sharon E. (Inventor); Thibeault, Sheila A. (Inventor); Bryant, Robert G. (Inventor)

    2016-01-01

    Methods for making a neutron converter layer are provided. The various embodiment methods enable the formation of a single layer neutron converter material. The single layer neutron converter material formed according to the various embodiments may have a high neutron absorption cross section, tailored resistivity providing a good electric field penetration with submicron particles, and a high secondary electron emission coefficient. In an embodiment method a neutron converter layer may be formed by sequential supercritical fluid metallization of a porous nanostructure aerogel or polyimide film. In another embodiment method a neutron converter layer may be formed by simultaneous supercritical fluid metallization of a porous nanostructure aerogel or polyimide film. In a further embodiment method a neutron converter layer may be formed by in-situ metalized aerogel nanostructure development.

  15. Magnetism in layered Ruthenates

    Energy Technology Data Exchange (ETDEWEB)

    Steffens, Paul C.

    2008-07-01

    In this thesis, the magnetism of the layered Ruthenates has been studied by means of different neutron scattering techniques. Magnetic correlations in the single-layer Ruthenates of the series Ca{sub 2-x}Sr{sub x}RuO{sub 4} have been investigated as function of Sr-concentration (x=0.2 and 0.62), temperature and magnetic field. These inelastic neutron scattering studies demonstrate the coexistence of ferromagnetic paramagnon scattering with antiferromagnetic fluctuations at incommensurate wave vectors. The temperature dependence of the amplitudes and energies of both types of excitations indicate the proximity to magnetic instabilities; their competition seems to determine the complex behavior of these materials. In Ca{sub 1.8}Sr{sub 0.2}RuO{sub 4}, which shows a metamagnetic transition, the ferromagnetic fluctuations are strongly suppressed at low temperature, but appear at higher temperature or application of a magnetic field. In the high-field phase of Ca{sub 1.8}Sr{sub 0.2}RuO{sub 4} above the metamagnetic transition, a ferromagnetic magnon dominates the excitation spectrum. Polarized neutron scattering revealed the existence of a very broad signal around the zone centre, in addition to the well-known incommensurate excitations at Q=(0.3,0.3,0) in the unconventional superconductor Sr{sub 2}RuO{sub 4}. With this additional contribution, it is possible to set up a general model for the Q-dependent magnetic susceptibility, which is well consistent with the results of other measurement methods that do not resolve the Q-dependence. Upon doping with Ti, the incommensurate fluctuations are enhanced, in particular near the critical concentration for the onset of magnetic order, but no divergence down to very low temperature is observed. In the bilayer Ti-doped Ca{sub 3}Ru{sub 2}O{sub 7}, the existence of magnetic order with a propagation vector of about ((1)/(4),(1)/(4),0) has been discovered and characterized in detail. Above and below T{sub N}, excitations at this

  16. Boundary-Layer & health

    Science.gov (United States)

    Costigliola, V.

    2010-09-01

    It has long been known that specific atmospheric processes, such as weather and longer-term climatic fluctuations, affect human health. The biometeorological literature refers to this relationship as meteorotropism, defined as a change in an organism that is correlated with a change in atmospheric conditions. Plenty of (patho)physiological functions are affected by those conditions - like the respiratory diseases - and currently it is difficult to put any limits for pathologies developed in reply. Nowadays the importance of atmospheric boundary layer and health is increasingly recognised. A number of epidemiologic studies have reported associations between ambient concentrations of air pollution, specifically particulate pollution, and adverse health effects, even at the relatively low concentrations of pollution found. Since 1995 there have been over twenty-one studies from four continents that have explicitly examined the association between ambient air pollutant mixes and daily mortality. Statistically significant and positive associations have been reported in data from various locations around the world, all with varying air pollutant concentrations, weather conditions, population characteristics and public health policies. Particular role has been given to atmospheric boundary layer processes, the impact of which for specific patient-cohort is, however, not well understood till now. Assessing and monitoring air quality are thus fundamental to improve Europe's welfare. One of current projects run by the "European Medical Association" - PASODOBLE will develop and demonstrate user-driven downstream information services for the regional and local air quality sectors by combining space-based and in-situ data with models in 4 thematic service lines: - Health community support for hospitals, pharmacies, doctors and people at risk - Public information for regions, cities, tourist industry and sporting event organizers - Compliance monitoring support on particulate

  17. Oxygen-reducing catalyst layer

    Energy Technology Data Exchange (ETDEWEB)

    O' Brien, Dennis P. (Maplewood, MN); Schmoeckel, Alison K. (Stillwater, MN); Vernstrom, George D. (Cottage Grove, MN); Atanasoski, Radoslav (Edina, MN); Wood, Thomas E. (Stillwater, MN); Yang, Ruizhi (Halifax, CA); Easton, E. Bradley (Halifax, CA); Dahn, Jeffrey R. (Hubley, CA); O' Neill, David G. (Lake Elmo, MN)

    2011-03-22

    An oxygen-reducing catalyst layer, and a method of making the oxygen-reducing catalyst layer, where the oxygen-reducing catalyst layer includes a catalytic material film disposed on a substrate with the use of physical vapor deposition and thermal treatment. The catalytic material film includes a transition metal that is substantially free of platinum. At least one of the physical vapor deposition and the thermal treatment is performed in a processing environment comprising a nitrogen-containing gas.

  18. Polymer-Layer Silicate Nanocomposites

    DEFF Research Database (Denmark)

    Potarniche, Catalina-Gabriela

    Nowadays, some of the material challenges arise from a performance point of view as well as from recycling and biodegradability. Concerning these aspects, the development of polymer layered silicate nanocomposites can provide possible solutions. This study investigates how to obtain polymer layered...... silicate nanocomposites and their structure-properties relationship. In the first part of the thesis, thermoplastic layered silicates were obtained by extrusion. Different modification methods were tested to observe the intercalation treatment effect on the silicate-modifier interactions. The silicate...

  19. Outer layer effects in wind-farm boundary layers: Coriolis forces and boundary layer height

    Science.gov (United States)

    Allaerts, Dries; Meyers, Johan

    2015-11-01

    In LES studies of wind-farm boundary layers, scale separation between the inner and outer region of the atmospheric boundary layer (ABL) is frequently assumed, i.e., wind turbines are presumed to fall within the inner layer and are not affected by outer layer effects. However, modern wind turbine and wind farm design tends towards larger rotor diameters and farm sizes, which means that outer layer effects will become more important. In a prior study, it was already shown for fully-developed wind farms that the ABL height influences the power performance. In this study, we use the in-house LES code SP-Wind to investigate the importance of outer layer effects on wind-farm boundary layers. In a suite of LES cases, the ABL height is varied by imposing a capping inversion with varying inversion strengths. Results indicate the growth of an internal boundary layer (IBL), which is limited in cases with low inversion layers. We further find that flow deceleration combined with Coriolis effects causes a change in wind direction throughout the farm. This effect increases with decreasing boundary layer height, and can result in considerable turbine wake deflection near the end of the farm. The authors are supported by the ERC (ActiveWindFarms, grant no: 306471). Computations were performed on VSC infrastructiure (Flemish Supercomputer Center), funded by the Hercules Foundation and the Flemish Government-department EWI.

  20. Sub-Transport Layer Coding

    DEFF Research Database (Denmark)

    Hansen, Jonas; Krigslund, Jeppe; Roetter, Daniel Enrique Lucani

    2014-01-01

    Packet losses in wireless networks dramatically curbs the performance of TCP. This paper introduces a simple coding shim that aids IP-layer traffic in lossy environments while being transparent to transport layer protocols. The proposed coding approach enables erasure correction while being...... oblivious to the congestion control algorithms of the utilised transport layer protocol. Although our coding shim is indifferent towards the transport layer protocol, we focus on the performance of TCP when ran on top of our proposed coding mechanism due to its widespread use. The coding shim provides gains...

  1. A POROUS, LAYERED HELIOPAUSE

    Energy Technology Data Exchange (ETDEWEB)

    Swisdak, M.; Drake, J. F. [Institute for Research in Electronics and Applied Physics, University of Maryland, College Park, MD 20742 (United States); Opher, M., E-mail: swisdak@umd.edu, E-mail: drake@umd.edu, E-mail: mopher@bu.edu [Department of Astronomy, Boston University, 725 Commonwealth Avenue, Boston, MA 02215 (United States)

    2013-09-01

    The picture of the heliopause (HP)-the boundary between the domains of the Sun and the local interstellar medium (LISM)-as a pristine interface with a large rotation in the magnetic field fails to describe recent Voyager 1 (V1) data. Magnetohydrodynamic (MHD) simulations of the global heliosphere reveal that the rotation angle of the magnetic field across the HP at V1 is small. Particle-in-cell simulations, based on cuts through the MHD model at V1's location, suggest that the sectored region of the heliosheath (HS) produces large-scale magnetic islands that reconnect with the interstellar magnetic field while mixing LISM and HS plasma. Cuts across the simulation reveal multiple, anti-correlated jumps in the number densities of LISM and HS particles, similar to those observed, at the magnetic separatrices. A model is presented, based on both the observations and simulations, of the HP as a porous, multi-layered structure threaded by magnetic fields. This model further suggests that contrary to the conclusions of recent papers, V1 has already crossed the HP.

  2. CHARGE-TRANSFER BETWEEN LAYERS IN MISFIT LAYER COMPOUNDS

    NARCIS (Netherlands)

    WIEGERS, GA

    1995-01-01

    Electron donation from MX double layers to TX(2) sandwiches, the interlayer bonding and the localization of conduction electrons in misfit layer compounds (MX)(p)(TX(2))(n) (M=Sn, Pb, Sb, Bi, rare earth metals; T=Ti, V, Cr, Nb, Ta; X=S, Se; 1.08

  3. Layer-by-Layer Proteomic Analysis of Mytilus galloprovincialis Shell.

    Directory of Open Access Journals (Sweden)

    Peng Gao

    Full Text Available Bivalve shell is a biomineralized tissue with various layers/microstructures and excellent mechanical properties. Shell matrix proteins (SMPs pervade and envelop the mineral crystals and play essential roles in biomineralization. Despite that Mytilus is an economically important bivalve, only few proteomic studies have been performed for the shell, and current knowledge of the SMP set responsible for different shell layers of Mytilus remains largely patchy. In this study, we observed that Mytilus galloprovincialis shell contained three layers, including nacre, fibrous prism, and myostracum that is involved in shell-muscle attachment. A parallel proteomic analysis was performed for these three layers. By combining LC-MS/MS analysis with Mytilus EST database interrogations, a whole set of 113 proteins was identified, and the distribution of these proteins in different shell layers followed a mosaic pattern. For each layer, about a half of identified proteins are unique and the others are shared by two or all of three layers. This is the first description of the protein set exclusive to nacre, myostracum, and fibrous prism in Mytilus shell. Moreover, most of identified proteins in the present study are novel SMPs, which greatly extended biomineralization-related protein data of Mytilus. These results are useful, on one hand, for understanding the roles of SMPs in the deposition of different shell layers. On the other hand, the identified protein set of myostracum provides candidates for further exploring the mechanism of adductor muscle-shell attachment.

  4. CHARGE-TRANSFER BETWEEN LAYERS IN MISFIT LAYER COMPOUNDS

    NARCIS (Netherlands)

    WIEGERS, GA

    1995-01-01

    Electron donation from MX double layers to TX(2) sandwiches, the interlayer bonding and the localization of conduction electrons in misfit layer compounds (MX)(p)(TX(2))(n) (M=Sn, Pb, Sb, Bi, rare earth metals; T=Ti, V, Cr, Nb, Ta; X=S, Se; 1.08

  5. Layer-by-Layer Proteomic Analysis of Mytilus galloprovincialis Shell

    Science.gov (United States)

    Wang, Xin-xing; Bao, Lin-fei; Fan, Mei-hua; Li, Xiao-min; Wu, Chang-wen; Xia, Shu-wei

    2015-01-01

    Bivalve shell is a biomineralized tissue with various layers/microstructures and excellent mechanical properties. Shell matrix proteins (SMPs) pervade and envelop the mineral crystals and play essential roles in biomineralization. Despite that Mytilus is an economically important bivalve, only few proteomic studies have been performed for the shell, and current knowledge of the SMP set responsible for different shell layers of Mytilus remains largely patchy. In this study, we observed that Mytilus galloprovincialis shell contained three layers, including nacre, fibrous prism, and myostracum that is involved in shell-muscle attachment. A parallel proteomic analysis was performed for these three layers. By combining LC-MS/MS analysis with Mytilus EST database interrogations, a whole set of 113 proteins was identified, and the distribution of these proteins in different shell layers followed a mosaic pattern. For each layer, about a half of identified proteins are unique and the others are shared by two or all of three layers. This is the first description of the protein set exclusive to nacre, myostracum, and fibrous prism in Mytilus shell. Moreover, most of identified proteins in the present study are novel SMPs, which greatly extended biomineralization-related protein data of Mytilus. These results are useful, on one hand, for understanding the roles of SMPs in the deposition of different shell layers. On the other hand, the identified protein set of myostracum provides candidates for further exploring the mechanism of adductor muscle-shell attachment. PMID:26218932

  6. Layer-by-Layer Proteomic Analysis of Mytilus galloprovincialis Shell.

    Science.gov (United States)

    Gao, Peng; Liao, Zhi; Wang, Xin-Xing; Bao, Lin-Fei; Fan, Mei-Hua; Li, Xiao-Min; Wu, Chang-Wen; Xia, Shu-Wei

    2015-01-01

    Bivalve shell is a biomineralized tissue with various layers/microstructures and excellent mechanical properties. Shell matrix proteins (SMPs) pervade and envelop the mineral crystals and play essential roles in biomineralization. Despite that Mytilus is an economically important bivalve, only few proteomic studies have been performed for the shell, and current knowledge of the SMP set responsible for different shell layers of Mytilus remains largely patchy. In this study, we observed that Mytilus galloprovincialis shell contained three layers, including nacre, fibrous prism, and myostracum that is involved in shell-muscle attachment. A parallel proteomic analysis was performed for these three layers. By combining LC-MS/MS analysis with Mytilus EST database interrogations, a whole set of 113 proteins was identified, and the distribution of these proteins in different shell layers followed a mosaic pattern. For each layer, about a half of identified proteins are unique and the others are shared by two or all of three layers. This is the first description of the protein set exclusive to nacre, myostracum, and fibrous prism in Mytilus shell. Moreover, most of identified proteins in the present study are novel SMPs, which greatly extended biomineralization-related protein data of Mytilus. These results are useful, on one hand, for understanding the roles of SMPs in the deposition of different shell layers. On the other hand, the identified protein set of myostracum provides candidates for further exploring the mechanism of adductor muscle-shell attachment.

  7. Natural melanin composites by layer-by-layer assembly

    Science.gov (United States)

    Eom, Taesik; Shim, Bong Sub

    2015-04-01

    Melanin is an electrically conductive and biocompatible material, because their conjugated backbone structures provide conducting pathways from human skin, eyes, brain, and beyond. So there is a potential of using as materials for the neural interfaces and the implantable devices. Extracted from Sepia officinalis ink, our natural melanin was uniformly dispersed in mostly polar solvents such as water and alcohols. Then, the dispersed melanin was further fabricated to nano-thin layered composites by the layer-by-layer (LBL) assembly technique. Combined with polyvinyl alcohol (PVA), the melanin nanoparticles behave as an LBL counterpart to from finely tuned nanostructured films. The LBL process can adjust the smart performances of the composites by varying the layering conditions and sandwich thickness. We further demonstrated the melanin loading degree of stacked layers, combination nanostructures, electrical properties, and biocompatibility of the resulting composites by UV-vis spectrophotometer, scanning electron microscope (SEM), multimeter, and in-vitro cell test of PC12, respectively.

  8. Layer-layer competition in multiplex complex networks

    CERN Document Server

    Gómez-Gardeñes, Jesús; Gutiérrez, Gerardo; Arenas, Alex; Gómez, Sergio

    2015-01-01

    The coexistence of multiple types of interactions within social, technological and biological networks has moved the focus of the physics of complex systems towards a multiplex description of the interactions between their constituents. This novel approach has unveiled that the multiplex nature of complex systems has strong influence in the emergence of collective states and their critical properties. Here we address an important issue that is intrinsic to the coexistence of multiple means of interactions within a network: their competition. To this aim, we study a two-layer multiplex in which the activity of users can be localized in each of the layer or shared between them, favoring that neighboring nodes within a layer focus their activity on the same layer. This framework mimics the coexistence and competition of multiple communication channels, in a way that the prevalence of a particular communication platform emerges as a result of the localization of users activity in one single interaction layer. Our...

  9. Layer-by-Layer Assembly of Enzymes on Carbon Nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jun; Liu, Guodong; Lin, Yuehe

    2008-06-01

    The use of Layer-by-layer techniques for immobilizing several types of enzymes, e.g. glucose oxidase (GOx), horse radish oxidases(HRP), and choline oxidase(CHO) on carbon nanotubes and their applications for biosenseing are presented. The enzyme is immobilized on the negatively charged CNT surface by alternatively assembling a cationic polydiallyldimethyl-ammonium chloride (PDDA) layer and a enzyme layer. The sandwich-like layer structure (PDDA/enzyme/PDDA/CNT) formed by electrostatic assembling provides a favorable microenvironment to keep the bioactivity of enzyme and to prevent enzyme molecule leakage. The morphologies and electrocatalytic acitivity of the resulted enzyme film were characterized using TEM and electrochemical techniques, respectively. It was found that these enzyme-based biosensors are very sensitive, selective for detection of biomolecules, e.g. glucose, choline.

  10. Influence of physical activity and dietary habits on lipid profile, blood pressure and BMI in subjects with metabolic syndrome Influencia de la actividad física y los hábitos nutricionales sobre el perfil lipídico, presión arterial e IMC en sujetos con síndrome metabólico

    Directory of Open Access Journals (Sweden)

    J. J. Muros Molina

    2011-10-01

    Full Text Available Background: The present study was determined the influence of physical activity and dietary habits on lipid profile, blood pressure (BP and body mass index (BMI in subjects with metabolic syndrome (MS. Aims: Identify the relationship between physical activity and proper nutrition and the probability of suffering from myocardial infarction (MI. Methods: Hundred chronically ill with MS who were active and followed a healthy diet were classified as compliant, while the remaining subjects were classified as non-compliant. Results: The compliant subjects show lower BMI values (30.8 ± 4.9 vs 32.5 ± 4.6, as well as lower levels of triacylglycerol (130.4 ± 48.2 vs 242.1 ± 90.1, total cholesterol (193.5 ± 39 vs 220.2 ± 52.3 and low-density lipoprotein cholesterol (105.2 ± 38.3 vs 139.2 ± 45. They show higher values in terms of high-density lipoprotein cholesterol levels (62.2 ± 20.1 vs 36.6 ± 15.3, with statistically significant differences. In terms of both systolic and diastolic pressure, no differences were revealed between the groups; however, those who maintain proper dietary habits show lower systolic blood pressure levels than the inactive subjects. The probability of suffering from MI greatly increases among the group of non-compliant subjects. Conclusions: Our results demonstrate how performing aerobic physical activity and following an individualized, Mediterranean diet significantly reduces MS indicators and the chances of suffering from MI.Introducción: En el presente estudio se determinó la influencia de la actividad física y los hábitos nutricionales sobre el perfil lipídico, presión arterial (PA e índice de masa corporal (IMC en sujetos con SM. Objetivos: Comprobar la relación entre realizar actividad física y una nutrición adecuada, y la posibilidad de sufrir infarto de miocardio (IM. Método: Se evaluaron 100 sujetos con SM. Los sujetos que manifestaban ser activos y llevaban una alimentación saludable fueron

  11. Bypass gástrico en Y de Roux para el tratamiento de pacientes con diabetes mellitus tipo II con IMC de 30 a 35 kg/m² Roux-en-Y gastric bypass for treatment of patients with DM type 2 and BMI of 30 to 35 Kg/m²

    Directory of Open Access Journals (Sweden)

    S. Navarrete Aulestia

    2012-08-01

    Full Text Available La incidencia de obesidad y una de sus comorbilidades más temida la diabetes mellitus tipo II está en aumento y no pareciera haber tratamiento médico que ayude a controlar estas pandemias. Existe una técnica quirúrgica bariátrica, el Bypass Gástrico en Y de Roux (BGYR que es segura y no sólo ayuda a controlar el exceso de peso sino también produce resultados alentadores en el control y remisión de la diabetes. Métodos: Se presentan 15 pacientes con IMC entre 30 y 35 kg/mt² diabéticos tipo II seleccionados sometidos a BGYR por laparoscopia con seguimiento de un año. Resultados: Se operaron 14 mujeres y un hombre con los siguientes valores promedios: Edad: 37 años, Peso: 88,3 kg, IMC: 32,8 kg/mt², Glicemia: 120 ± 38,8 mg%, HbA1c: 7,6% ± 0,73. 40% de hipertensión arterial y 33,3% dislipidémicos. El tiempo quirúrgico promedio fue de 75 minutos, dos días de hospitalización bajo índice de complicaciones y sin mortalidad. Se logró una remisión de la diabetes en el 93%, de los casos, con descensos de la glicemia y HbA1c significativos (p ≤ 0,05 y p ≤ 0,001 respectivamente con un control de la dislipidemia del 100% y 83,3% de la HTA. Conclusiones: El BGYR en obesos tipo I diabéticos seleccionados es una técnica segura y eficaz en el control metabólico y de la obesidad.Background: The incidence of obesity and its most feared comorbidity, diabetes mellitus type 2, is increasing and there would not seem to be any medical treatment to help control these pandemics. However, there is a bariatric surgery technique, the Roux-en-Y Gastric Bypass (RYGB, which is safe and not only helps control excess weight, but produces encouraging results in the control and remission of diabetes. Methods: We present 15 selected patients with a BMI between 30 and 35 kg/mt² and diabetes type 2 who underwent a laparoscopic RYGB with of one-year follow-up. Results: A total of 14 women and one man were operated with the following average values: age

  12. Distribución del indice de masa corporal (IMC y prevalencia de obesidad primaria en niños pre-púberes de 6 a 10 años de edad en el distrito de San Martín de Porres - Lima

    Directory of Open Access Journals (Sweden)

    Felix Konrad Llanos Tejada

    2003-07-01

    Full Text Available La obesidad en niños y adolescentes está experimentando, a nivel mundial, un incremento progresivo en su prevalencia, del cual nuestro país no es ajeno. Objetivo: Describir la distribución del índice de masa corporal y determinar la prevalencia de obesidad en escolares pre púberes de 6 a 10 años de edad en el distrito de San Martín de Porres de la provincia de Lima. Material y Métodos: Fueron seleccionados al azar 1636 escolares (879 del sexo masculino y 757 del sexo femenino pre púberes de 6 a 10 años de edad de seis centros educativos estatales del distrito de San Martín de Porres, distribuidos en cinco grupos etarios. Resultados: Nuestros resultados muestran una prevalencia de sobrepeso de 9.90% y de obesidad de 5.57% en varones, y una prevalencia de sobrepeso de 9.78% y de obesidad de 5.55% en mujeres, sin diferencias estadísticamente significativas entre ambos sexos en la prevalencia de sobrepeso (p = 0.244 y obesidad (p = 0.234. La comparación de nuestros resultados con los reportes del NHANES III de 1994 mostró una diferencia estadísticamente significativa (p<0.01. Conclusión: Concluimos que la población estudiada presenta alta prevalencia de sobrepeso (9.96% y baja prevalencia de obesidad (5.62% y recomendamos la utilización de la tabla de distribución por percentiles del IMC de este estudio.

  13. The layer by layer selective laser synthesis of ruby

    Directory of Open Access Journals (Sweden)

    Vlasova M.

    2010-01-01

    Full Text Available In the work, features of the layer-by-layer selective laser synthesis (SLS of ruby from an Al2O3-Cr2O3 mixture are considered depending on the irradiation power, the laser beam traverse speed, the height and amount of the backfill of powder layers. It has been established that, under irradiation, a track consisting of polycrystalline textured ruby forms. The morphology of the surface of the track and its crystalline structure are determined by the irradiation conditions.

  14. Layer-by-layer magnetometry of polarizing supermirrors

    CERN Document Server

    Ruecker, U; Toperverg, B; Brueckel, T; Ott, F

    2002-01-01

    We investigate the remagnetization behaviour of remanent polarizing supermirrors by polarized neutron reflectometry. Such a mirror can be remagnetized in a magnetic field of 30 mT. It is shown, that at lower fields, the mirror is not completely remagnetized, but the magnetization of the thinner layers can be flipped more easily than the magnetization of the thicker layers. With polarized neutron reflectometry, we are able to find out exactly how many layers are magnetized parallel and how many are magnetized antiparallel to the external field. Furthermore, information about structural and magnetic imperfections (roughness, domain formation) is available. (orig.)

  15. D0 layer 0 innermost layer of silicon microstrip tracker

    Energy Technology Data Exchange (ETDEWEB)

    Hanagaki, K.; /Fermilab

    2006-01-01

    A new inner layer silicon strip detector has been built and will be installed in the existing silicon microstrip tracker in D0. They report on the motivation, design, and performance of this new detector.

  16. Director of IMCS - National Prize Laureate of Moldova

    Directory of Open Access Journals (Sweden)

    Editorial board of the "Computer Science Journal of Moldova"

    2012-02-01

    Full Text Available Director of the Institute of Mathematics and Computer Science, Vice Editor-in-Chief of CSJM, and our colleague, D.Hab. Svetlana Cojocaru, in 2011 became the National Prize Laureate of Moldova. In accordance with Government decision, this distinction is given for ``outstanding achievements whose results have substantially enriched science, culture and art, had a considerable contribution to promoting a positive image of the country in the international arena, a significant impact on the development of socio-economic, scientific and technical progress, national and world culture.''

  17. Reading, Writing, and Research: A Writing Center in the IMC.

    Science.gov (United States)

    Pitel, Vonna J.

    1991-01-01

    Discusses the advantages of making the writing center part of the instructional media center in schools and provides some questions to consider in setting up a writing center. Offers three examples of popular writing assignments. (MG)

  18. IMC/RMC Network Professional Film Collection. Second Edition.

    Science.gov (United States)

    Council for Exceptional Children, Reston, VA. Information Center on Exceptional Children.

    The catalog lists and describes approximately 293 films concerning handicapped children which are available from the Instructional Materials Centers and Regional Media Centers Network. Films are organized under the following categories (number of films for each category is indicated in parentheses): art for exceptional children (five), autism…

  19. IMC,中国药企了解多少

    Institute of Scientific and Technical Information of China (English)

    蒋庆东

    2003-01-01

    @@ 整合营销传播(Integrated Marketing Communications),已成为自20世纪90年代以来广告界的主流,营销界的热门话题.但是在我国,尤其是医药界,IMC理论基本上没有得到应用,被营销界推崇的成功案例都是些短期策划、炒作行为,业界"成功"的企业挥动的市场利刃是广告或者价格,营销等同于销售,广告代替了传播,这些单一的销售手段被各类企业屡屡应用,一时间,垃圾广告满天飞,消费者耳边整天充满了降价的叫嚣声,我不禁想问,你们究竟想对目标受众传播什么样的信息,又想和他们沟通什么?

  20. Output constrained IMC controllers in control systems of electromechanical actuators

    Institute of Scientific and Technical Information of China (English)

    Piotr M MARUSAK; Suwat KUNTANAPREEDA

    2015-01-01

    Electromechanical actuators are widely used in many industrial applications. There are usually some constraints existing in a designed system. This paper proposes a simple method to design constrained controllers for electromechanical actuators. The controllers merge the ideas exploited in internal model control and model predictive control. They are designed using the standard control system structure with unity negative feedback. The structure of the controllers is relatively simple as well as the design process. The output constraint handling mechanism is based on prediction of the control plant behavior many time steps ahead. The mechanism increases control performance and safety of the control plant. The benefits offered by the proposed controllers have been demonstrated in real-life experiments carried out in control systems of two electromechanical actuators:a DC motor and an electrohydraulic actuator.

  1. Simulation Study of IMC and Fuzzy Controller for HVAC System

    Directory of Open Access Journals (Sweden)

    Umamaheshwari

    2009-06-01

    Full Text Available This paper presents how the fuzzy logic controller is used to solve the control problems of complex and non linear process and show that it is more robust and their performance are less sensitive to parametric variations than conventional controllers. These systems will yield a linear response when compared to ordinary controllers. The main advantage of Fuzzy control over conventional controllers is regulation can be done without over shoot.

  2. Boundary layers in stochastic thermodynamics.

    Science.gov (United States)

    Aurell, Erik; Mejía-Monasterio, Carlos; Muratore-Ginanneschi, Paolo

    2012-02-01

    We study the problem of optimizing released heat or dissipated work in stochastic thermodynamics. In the overdamped limit these functionals have singular solutions, previously interpreted as protocol jumps. We show that a regularization, penalizing a properly defined acceleration, changes the jumps into boundary layers of finite width. We show that in the limit of vanishing boundary layer width no heat is dissipated in the boundary layer, while work can be done. We further give an alternative interpretation of the fact that the optimal protocols in the overdamped limit are given by optimal deterministic transport (Burgers equation).

  3. Layer-by-Layer Insight into Electrostatic Charge Distribution of Few-Layer Graphene

    Science.gov (United States)

    Rokni, Hossein; Lu, Wei

    2017-01-01

    In few-layer graphene (FLG) systems on a dielectric substrate such as SiO2, the addition of each extra layer of graphene can drastically alter their electronic and structural properties. Here, we map the charge distribution among the individual layers of finite-size FLG systems using a novel spatial discrete model that describes both electrostatic interlayer screening and fringe field effects. Our results reveal that the charge density in the region very close to the edges is screened out an order of magnitude more weakly than that across the central region of the layers. Our discrete model suggests that the interlayer charge screening length in 1–8 layer thick graphene systems depends mostly on the overall gate/molecular doping level rather than on temperature, in particular at an induced charge density >5 × 1012 cm−2, and can reliably be determined to be larger than half the interlayer spacing but shorter than the bilayer thickness. Our model can be used for designing FLG-based devices, and offers a simple rule regarding the charge distribution in FLG: approximately 70%, 20%, 6% and 3% (99% overall) of the total induced charge density reside within the four innermost layers, implying that the gate-induced electric field is not definitely felt by >4th layer. PMID:28220816

  4. Layer-by-Layer Insight into Electrostatic Charge Distribution of Few-Layer Graphene

    Science.gov (United States)

    Rokni, Hossein; Lu, Wei

    2017-02-01

    In few-layer graphene (FLG) systems on a dielectric substrate such as SiO2, the addition of each extra layer of graphene can drastically alter their electronic and structural properties. Here, we map the charge distribution among the individual layers of finite-size FLG systems using a novel spatial discrete model that describes both electrostatic interlayer screening and fringe field effects. Our results reveal that the charge density in the region very close to the edges is screened out an order of magnitude more weakly than that across the central region of the layers. Our discrete model suggests that the interlayer charge screening length in 1–8 layer thick graphene systems depends mostly on the overall gate/molecular doping level rather than on temperature, in particular at an induced charge density >5 × 1012 cm‑2, and can reliably be determined to be larger than half the interlayer spacing but shorter than the bilayer thickness. Our model can be used for designing FLG-based devices, and offers a simple rule regarding the charge distribution in FLG: approximately 70%, 20%, 6% and 3% (99% overall) of the total induced charge density reside within the four innermost layers, implying that the gate-induced electric field is not definitely felt by >4th layer.

  5. Atomic layer deposition for semiconductors

    CERN Document Server

    Hwang, Cheol Seong

    2014-01-01

    This edited volume discusses atomic layer deposition (ALD) for all modern semiconductor devices, moving from the basic chemistry of ALD and modeling of ALD processes to sections on ALD for memories, logic devices, and machines.

  6. Magnetic microscopy of layered structures

    CERN Document Server

    Kuch, Wolfgang; Fischer, Peter; Hillebrecht, Franz Ulrich

    2015-01-01

    This book presents the important analytical technique of magnetic microscopy. This method is applied to analyze layered structures with high resolution. This book presents a number of layer-resolving magnetic imaging techniques that have evolved recently. Many exciting new developments in magnetism rely on the ability to independently control the magnetization in two or more magnetic layers in micro- or nanostructures. This in turn requires techniques with the appropriate spatial resolution and magnetic sensitivity. The book begins with an introductory overview, explains then the principles of the various techniques and gives guidance to their use. Selected examples demonstrate the specific strengths of each method. Thus the book is a valuable resource for all scientists and practitioners investigating and applying magnetic layered structures.

  7. National Flood Hazard Layer (NFHL)

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The National Flood Hazard Layer (NFHL) is a compilation of GIS data that comprises a nationwide digital Flood Insurance Rate Map. The GIS data and services are...

  8. Hurricane Boundary-Layer Theory

    Science.gov (United States)

    2010-01-01

    2501. Kundu PK. 1990. Fluid Mechanics . Academic Press: San Diego, USA. Kuo HL. 1982. Vortex boundary layer under quadratic surface stress. Boundary...identification of two mechanisms for the spin-up of the mean tangential circulation of a hurricane. The first involves convergence of absolute angular...momentum above the boundary layer, where this quantity is approximately conserved. This mechanism acts to spin up the outer circulation at radii

  9. Photocurrent generation in organic photodetectors with tailor-made active layers fabricated by layer-by-layer deposition.

    Science.gov (United States)

    Vonhoeren, Benjamin; Dalgleish, Simon; Hu, Laigui; Matsushita, Michio M; Awaga, Kunio; Ravoo, Bart Jan

    2015-04-08

    Photodetectors supply an electric response when illuminated. The detectors in this study consist of an active layer and a polyvinylidene fluoride (PVDF) blocking layer, which are sandwiched by an aluminum and an indium tin oxide (ITO) electrode. The active layer was prepared of Zn porphyrins and assembled by covalent layer-by-layer (LbL) deposition. Layer growth was monitored by UV-vis absorbance, ellipsometry, and X-ray photoelectron spectroscopy. Upon exposure to chopped light, the detectors show an alternating transient photocurrent, which is limited by the accumulation of space charges at the blocking layer/active layer interface. We could show that the number of photoactive layers has a significant impact on device performance. The fastest response was achieved with fewer layers. The highest photocurrents were measured for detectors with an intermediate number of layers, beyond which, more layers did not lead to an increase in the photocurrent despite containing more active material.

  10. Hybrid window layer for photovoltaic cells

    Science.gov (United States)

    Deng, Xunming

    2010-02-23

    A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.

  11. Layer-by-layer films for biomedical applications

    CERN Document Server

    Picart, Catherine; Voegel, Jean-Claude

    2015-01-01

    The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance. In the last 15 years the LbL technique has seen considerable developments and has now reached a point where it is beginning to find applications in bioengineering and biomedical engineering. The book gives a thorough overview of applications of the LbL technique in the c

  12. DAR Assisted Layer-by-Layer Assembly of Aromatic Compounds

    Institute of Scientific and Technical Information of China (English)

    姜思光; 陈晓东; 张莉; 刘鸣华

    2003-01-01

    A facile DAR (diphenylamine-4-diazonium-formaldehyde resin)assisted layer-by-layer (LbL) assembly of uitrathin organic film of aromatic compounds has been investigated. The muitilayer of pyrene or anthracene was fabricated through simple dipping of the glass slide into the mixed solution of DAR with the target compounds. In this method, DAR acted as an assistant compound to help the assembling of the aromatic compounds. Such a convenient deposition method not only reserves the advantages of the traditional LbL technique but also simplifies the technique and extends the effectiveness of LbL technique to small molecules without any charge.

  13. Catalysts, Protection Layers, and Semiconductors

    DEFF Research Database (Denmark)

    Chorkendorff, Ib

    2015-01-01

    Hydrogen is the simplest solar fuel to produce and in this presentation we shall give a short overview of the pros and cons of various tandem devices [1]. The large band gap semiconductor needs to be in front, but apart from that we can chose to have either the anode in front or back using either...... acid or alkaline conditions. Since most relevant semiconductors are very prone to corrosion the advantage of using buried junctions and using protection layers offering shall be discussed [2-4]. Next we shall discuss the availability of various catalysts for being coupled to these protections layers...... and how their stability may be evaluated [5, 6]. Examples of half-cell reaction using protection layers for both cathode and anode will be discussed though some of recent examples under both alkaline and acidic conditions. Si is a very good low band gap semiconductor and by using TiO2 as a protection...

  14. Boundary layer control for airships

    Science.gov (United States)

    Pake, F. A.; Pipitone, S. J.

    1975-01-01

    An investigation is summarized of the aerodynamic principle of boundary layer control for nonrigid LTA craft. The project included a wind tunnel test on a BLC body of revolution at zero angle of attack. Theoretical analysis is shown to be in excellent agreement with the test data. Methods are evolved for predicting the boundary layer development on a body of revolution and the suction pumping and propulsive power requirements. These methods are used to predict the performance characteristics of a full-scale airship. The analysis indicates that propulsive power reductions of 15 to 25 percent and endurance improvements of 20 to 40 percent may be realized in employing boundary-layer control to nonrigid airships.

  15. Supermolecular layered dou- ble hydroxides

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Research progresses in the layered double hydroxides ·mH2O intercalated with metal coordinate ions or oxometalates in the last ten years are reviewed. These layered double hydroxides are mainly intercalated with polyoxometalate (POM) ions, a LiAl-LDH photochemical assembly containing TiO2 and CH3(CH2)12COO- anions, together with Zn(TPPC) (porphy-rin derivate) and macrocyclic ligand-containing porphyrin derivate anions. Emphasis is put on the synthesis methods for intercalation of the anions into the interlayer regions, the characterization techniques and structures for the layered compounds and the newest research progress in the fields such as catalysis. The review also forecasts the prospects of the field.

  16. The aqueous thermal boundary layer

    Science.gov (United States)

    Katsaros, Kristina B.

    1980-02-01

    This article reviews the available data, measurement techniques, and present understanding of the millimeter thick aqueous thermal boundary layer. A temperature difference between the surface and lower strata, δT, of the order of a few tenths to -1 °C have been observed. Techniques ranging from miniature mercury thermometers and electrical point sensors to optical interferometry and infrared radiometry have been employed. Many processes influence the temperature structure in this thin boundary layer. Among them are: the net upward heat flux due to evaporation and sensible heat transfer; infrared and solar radiation; and the turbulence near the interface due to wind mixing, wave breaking and current shear. Presence of solute and surface-active materials stimulate or dampen these mixing processes thereby influencing boundary-layer thickness and temperature structure.

  17. Asymptotic analysis and boundary layers

    CERN Document Server

    Cousteix, Jean

    2007-01-01

    This book presents a new method of asymptotic analysis of boundary-layer problems, the Successive Complementary Expansion Method (SCEM). The first part is devoted to a general comprehensive presentation of the tools of asymptotic analysis. It gives the keys to understand a boundary-layer problem and explains the methods to construct an approximation. The second part is devoted to SCEM and its applications in fluid mechanics, including external and internal flows. The advantages of SCEM are discussed in comparison with the standard Method of Matched Asymptotic Expansions. In particular, for the first time, the theory of Interactive Boundary Layer is fully justified. With its chapter summaries, detailed derivations of results, discussed examples and fully worked out problems and solutions, the book is self-contained. It is written on a mathematical level accessible to graduate and post-graduate students of engineering and physics with a good knowledge in fluid mechanics. Researchers and practitioners will estee...

  18. The Lowest Atmosphere: Atmospheric Boundary Layer Including Atmospheric Surface Layer.

    Science.gov (United States)

    1996-04-01

    of motion of the atmosphere— "second order closure"—to such applications as the SCIPUFF -PC code for tracer dispersion (see Sykes, 1994). Now, for...Turbulence, Methuen, London, 2nd Ed., 1955. Sykes, R.I., "The SCIPUFF -PC Code," ARAP Draft Report, 1994. Tennekes, H., "The Atmospheric Boundary Layer

  19. Electrostatic layer-by-layer construction of fibrous TMV biofilms.

    Science.gov (United States)

    Tiu, Brylee David B; Kernan, Daniel L; Tiu, Sicily B; Wen, Amy M; Zheng, Yi; Pokorski, Jonathan K; Advincula, Rigoberto C; Steinmetz, Nicole F

    2017-01-26

    As nature's choice in designing complex architectures, the bottom-up assembly of nanoscale building blocks offers unique solutions in achieving more complex and smaller morphologies with wide-ranging applications in medicine, energy, and materials science as compared to top-down manufacturing. In this work, we employ charged tobacco mosaic virus (TMV-wt and TMV-lys) nanoparticles in constructing multilayered fibrous networks via electrostatic layer-by-layer (LbL) deposition. In neutral aqueous media, TMV-wt assumes an anionic surface charge. TMV-wt was paired with a genetically engineered TMV-lys variant that displays a corona of lysine side chains on its solvent-exposed surface. The electrostatic interaction between TMV-wt and TMV-lys nanoparticles became the driving force in the highly controlled buildup of the multilayer TMV constructs. Since the resulting morphology closely resembles the 3-dimensional fibrous network of an extracellular matrix (ECM), the capability of the TMV assemblies to support the adhesion of NIH-3T3 fibroblast cells was investigated, demonstrating potential utility in regenerative medicine. Lastly, the layer-by-layer deposition was extended to release the TMV scaffolds as free-standing biomembranes. To demonstrate potential application in drug delivery or vaccine technology, cargo-functionalized TMV biofilms were programmed.

  20. Waist circumference is better associated with high density lipoprotein (HDL-c than with body mass index (BMI in adults with metabolic syndrome Circunferencia de la cintura es mejor asociado con lipoproteínas de alta densidad (LAD-C que con el índice de masa corporal (IMC en adultos con síndrome metabólico

    Directory of Open Access Journals (Sweden)

    S. T. Arimura

    2011-12-01

    Full Text Available Background: The measurement of waist circumference (WC is the most prevalent cause of the metabolic syndrome (MS. Objective: The aim of this study was to correlate WC and BMI with high-density lipoprotein (HDL-c levels in patients with MS being consulted by the Family Health Program (PSF, Brazil. Methods: This cross-sectional study was conducted from September to November 2008 with 42 patients (29 women and 13 men from 35 to 77 years. Dietary intake was reported, and biochemical and body composition measures were taken. Results: The HDL-c levels were higher in women when compared to men (48.4 ± 8.1 mg/dL vs. 36.4 ± 7.8 mg/dL. However, the triglycerides (TG/HDL-c ratio and TG concentrations were lower in women (3.8 ± 1.5 and 178.0 ± 57.8 mg/dL, respectively than in men (9.4 ± 8.5 and 471.5 ± 501.5 mg/dL, respectively. Regarding skinfold profile, the triceps was greater in females (37.0 ± 8.4 cm vs. 20.7 ± 10.5 cm. The dietetic profile showed that women had a lower intake of energy, fiber, phosphorus and sodium. The fruits and vegetables intake was diminished in the participants of this study, as less than 60% of the women and 50% of men met the daily recommendations. Approximately 54% of men and 28% of women had a lower intake of dairy products daily. Moreover, the results shows that the WC was negatively correlated to HDL-c (r = -0.41, p 0.06. Conclusion: Our findings showed that WC is a better predictor of changes in HDL-c than BMI.Antecedentes: La medición de la circunferencia de la cintura (CC es la causa más prevalente del síndrome metabólico (SM. Objetivo: el propósito de este estudio fue correlacionar la CC y el IMC con las concentraciones de lipoproteínas de densidad elevada (HDL-c en pacientes con SM vistos en consulta del Programa de salud familiar (PSF, de Brasil. Métodos: Este estudio trasversal se realizó entre septiembre y noviembre de 2008 en 42 pacientes (29 mujeres y 13 hombres de 35 a 77 años. Se registró la

  1. Nonparallel stability of boundary layers

    Science.gov (United States)

    Nayfeh, Ali H.

    1987-01-01

    The asymptotic formulations of the nonparallel linear stability of incompressible growing boundary layers are critically reviewed. These formulations can be divided into two approaches. The first approach combines a numerical method with either the method of multiple scales, or the method of averaging, of the Wentzel-Kramers-Brillouin (WKB) approximation; all these methods yield the same result. The second approach combined a multi-structure theory with the method of multiple scales. The first approach yields results that are in excellent agreement with all available experimental data, including the growth rates as well as the neutral stability curve. The derivation of the linear stability of the incompressible growing boundary layers is explained.

  2. Operating System Abstraction Layer (OSAL)

    Science.gov (United States)

    Yanchik, Nicholas J.

    2007-01-01

    This viewgraph presentation reviews the concept of the Operating System Abstraction Layer (OSAL) and its benefits. The OSAL is A small layer of software that allows programs to run on many different operating systems and hardware platforms It runs independent of the underlying OS & hardware and it is self-contained. The benefits of OSAL are that it removes dependencies from any one operating system, promotes portable, reusable flight software. It allows for Core Flight software (FSW) to be built for multiple processors and operating systems. The presentation discusses the functionality, the various OSAL releases, and describes the specifications.

  3. Thermohaline structure and circulation in the upper layers of the southern Bay of Bengal during BOBMEX-Pilot (October — November 1998)

    Indian Academy of Sciences (India)

    V Ramesh Babu; V S N Murty; L V G Rao; C V Prabhu; V Tilvi

    2000-06-01

    Hydrographic data collected on board ORV Sagar Kanya in the southern Bay of Bengal during the BOBMEX-Pilot programme (October - November 1998) have been used to describe the thermohaline structure and circulation in the upper 200 m water column of the study region. The presence of seasonal Inter-Tropical Convergence Zone (ITCZ) over the study area, typically characterized with enhanced cloudiness and flanked by the respective east/northeast winds on its northern part and west/southwest winds on its southern part, has led to net surface heat loss of about 55 W/m2. The sea surface dynamic topography relative to 500 db shows that the upper layer circulation is characterised by a cyclonic gyre encompassing the study area. The eastward flowing Indian Monsoon Current (IMC) between 5° N and 7° N in the south and its northward branching along 87° E up to 13° N appear to feed the cyclonic gyre. The Vessel-Mounted Acoustic Doppler Current Profiler (VM-ADCP) measured currents confirm the presence of the cyclonic gyre in the southern Bay of Bengal during the withdrawing phase of the southwest monsoon from the northern/central parts of the Bay of Bengal.

  4. Prediction of turbulent shear layers in turbomachines

    Science.gov (United States)

    Bradshaw, P.

    1974-01-01

    The characteristics of turbulent shear layers in turbomachines are compared with the turbulent boundary layers on airfoils. Seven different aspects are examined. The limits of boundary layer theory are investigated. Boundary layer prediction methods are applied to analysis of the flow in turbomachines.

  5. Improving modeling with layered UML diagrams

    DEFF Research Database (Denmark)

    Störrle, Harald

    2013-01-01

    Layered diagrams are diagrams whose elements are organized into sets of layers. Layered diagrams are routinely used in many branches of engineering, except Software Engineering. In this paper, we propose to add layered diagrams to UML modeling tools, and elaborate the concept by exploring usage...

  6. Adhesion Between Poly(dimethylsiloxane) Layers

    DEFF Research Database (Denmark)

    Yu, Liyun; Daugaard, Anders Egede; Skov, Anne Ladegaard

    Different adhesion methods of poly(dimethylsiloxane) (PDMS) layers were studied with respect to adhesional force and the resulting rheology of the two-layered PDMS films were investigated. The role of adhesion between PDMS layers on the performances of two-layer structures was studied with peel...

  7. Doped LZO buffer layers for laminated conductors

    Science.gov (United States)

    Paranthaman, Mariappan Parans [Knoxville, TN; Schoop, Urs [Westborough, MA; Goyal, Amit [Knoxville, TN; Thieme, Cornelis Leo Hans [Westborough, MA; Verebelyi, Darren T [Oxford, MA; Rupich, Martin W [Framingham, MA

    2010-03-23

    A laminated conductor includes a metallic substrate having a surface, a biaxially textured buffer layer supported by the surface of the substrate, the biaxially textured buffer layer comprising LZO and a dopant for mitigating metal diffusion through the LZO, and a biaxially textured conductor layer supported by the biaxially textured buffer layer.

  8. High Performance Thin Layer Chromatography.

    Science.gov (United States)

    Costanzo, Samuel J.

    1984-01-01

    Clarifies where in the scheme of modern chromatography high performance thin layer chromatography (TLC) fits and why in some situations it is a viable alternative to gas and high performance liquid chromatography. New TLC plates, sample applications, plate development, and instrumental techniques are considered. (JN)

  9. Shockwave-boundary layer interactions

    NARCIS (Netherlands)

    Glepman, R.

    2014-01-01

    Shock wave-boundary layer interactions are a very common feature in both transonic and supersonic flows. They can be encountered on compressor and turbine blades, in supersonic jet inlets, on transonic wings, on the stabilization fins of missiles and in many more situations. Because of their major i

  10. the Martian atmospheric boundary layer

    DEFF Research Database (Denmark)

    Petrosyan, A.; Galperin, B.; Larsen, Søren Ejling

    2011-01-01

    The planetary boundary layer (PBL) represents the part of the atmosphere that is strongly influenced by the presence of the underlying surface and mediates the key interactions between the atmosphere and the surface. On Mars, this represents the lowest 10 km of the atmosphere during the daytime...

  11. High Performance Thin Layer Chromatography.

    Science.gov (United States)

    Costanzo, Samuel J.

    1984-01-01

    Clarifies where in the scheme of modern chromatography high performance thin layer chromatography (TLC) fits and why in some situations it is a viable alternative to gas and high performance liquid chromatography. New TLC plates, sample applications, plate development, and instrumental techniques are considered. (JN)

  12. Properties Research of Ceramic Layer

    Directory of Open Access Journals (Sweden)

    Z. Żółkiewicz

    2012-12-01

    Full Text Available In the method of full mould the polystyrene model, which fills the mould cavity in the course of filling by the liquid metal is subjected tothe influence of high temperature and passes from the solid, through the liquid, to the gaseous state. During this process solid and gaseousproducts of thermal decomposition of polystyrene patterns occur. The kinetics of this process is significantly influenced by the gasificationtemperature, density and mass of the polystyrene patterns. One of the basic parameters is the amount and rate of gas from the polystyrenemodel during its thermal decomposition. Specific properties of ceramic layer used for lost foam castings are required. To ensure optimalprocess flow of metal in the form proper permeability of the ceramic layer is needed.To ensure optimal conditions for technological casting method EPS patterns are tested and determined are the technological parametersand physical-chemical process in: material properties of the pattern, properties of the ceramic layer applied to the pattern, pattern gasification kinetics pouring processIn the course of the research the characteristics of polystyrene and ceramic layer were determined.

  13. Stability of Boundary Layer Flow.

    Science.gov (United States)

    1980-03-01

    and Teske (1975). We can conclude (as in the case of ducting) that theoretical models of boundary layer structure and associated radar structure...FI33 (Secret). Hitney, (1978) "Surface Duct Effects," Naval Ocean Systems Center, San Diego, Calif., Report No. TD144. Lewellen, W. S., and M. E. Teske

  14. Organic photovoltaic cells utilizing ultrathin sensitizing layer

    Science.gov (United States)

    Rand, Barry P.; Forrest, Stephen R.

    2011-05-24

    A photosensitive device includes a series of organic photoactive layers disposed between two electrodes. Each layer in the series is in direct contact with a next layer in the series. The series is arranged to form at least one donor-acceptor heterojunction, and includes a first organic photoactive layer comprising a first host material serving as a donor, a thin second organic photoactive layer comprising a second host material disposed between the first and a third organic photoactive layer, and the third organic photoactive layer comprising a third host material serving as an acceptor. The first, second, and third host materials are different. The thin second layer serves as an acceptor relative to the first layer or as a donor relative to the third layer.

  15. Cyclone with boundary layer displacement

    Energy Technology Data Exchange (ETDEWEB)

    Gorton-Huelgerth, A.; Hoffmann, D.; Staudinger, G. [Technische Universitaet Graz, Graz (Austria). Inst. fuer Verfahrenstechnik, Abt. fuer Apparatebau und Mechanische Verfahrenstechnik

    1998-12-31

    In a cyclone the boundary layers at the cover plate and outside of the vortex finder are considered to affect the separation efficiency of a cyclone. To improve separation efficiency, the boundary layers at and the space between vortex finder and cover plate were investigated. Two identical cyclones, 400 mm diameter and 990 mm long were manufactured with high precision from stainless steel. One was equipped with openings for insertion of velocity probes; the opening could be closed with glass windows to allow Laser Doppler Anemometry. The other cyclone was used for testing separation efficiency. Velocity measurements by both conventional pressure probes and Laser Doppler Anemometry revealed that only a minor part of the boundary layer at the outside of the vortex finder reaches the lower end of it, because the axial velocity is slowed down drastically. Light sheet visualization showed that there exists a heavily particle loaded boundary layer at the cover plate. There are no particles at the lower part of the vortex finder. This can be explained by the radial mass exchange. The effect of vortex finder length on separation efficiency was investigated by varying the length of the vortex finder and measuring the separation efficiency using a limestone powder as test material. It was found that the separation efficiency is not sensitive to the length of the vortex finder. Particle slip increases only where the vortex finder is definitely shorter than its diameter. It was tried to improve the separation efficiency by introducing an air curtain along the vortex finder. The positive effect on separation efficiency and particle cut size is minimal. Results from velocity measurements with cylinder pressure probes in the boundary layer do not fit the results from other measurement techniques. Many older measurements were made with these probes. The conclusions drawn and the design rules deduced are to be questioned. 17 refs., 21 figs., 2 tabs.

  16. A microstructural analysis of solder joints from the electronic assemblies of dismantled nuclear weapons

    Energy Technology Data Exchange (ETDEWEB)

    Vianco, P.T.; Rejent, J.A. [Sandia National Labs., Albuquerque, NM (United States). Materials Joining Dept.

    1997-05-01

    MC1814 Interconnection Boxes from dismantled B57 bombs, and MC2839 firing Sets from retired W70-1 warheads were obtained from the Pantex facility. Printed circuit boards were selected from these components for microstructural analysis of their solder joints. The analysis included a qualitative examination of the solder joints and quantitative assessments of (1) the thickness of the intermetallic compound layer that formed between the solder and circuit board Cu features, and (2) the Pb-rich phase particle distribution within the solder joint microstructure. The MC2839 solder joints had very good workmanship qualities. The intermetallic compound layer stoichiometry was determined to be that of Cu6Sn5. The mean intermetallic compound layer thickness for all solder joints was 0.885 mm. The magnitude of these values did not indicate significant growth over the weapon lifetime. The size distribution of the Pb-rich phase particles for each of the joints were represented by the mean of 9.85 {times} 10{sup {minus}6} mm{sup 2}. Assuming a spherical geometry, the mean particle diameter would be 3.54 mm. The joint-to-joint difference of intermetallic compound layer thickness and Pb-rich particle size distribution was not caused by varying thermal environments, but rather, was a result of natural variations in the joint microstructure that probably existed at the time of manufacture. The microstructural evaluation of the through-hole solder joints form the MC2839 and MC1814 components indicated that the environmental conditions to which these electronic units were exposed in the stockpile, were benign regarding solder joint aging. There was an absence of thermal fatigue damage in MC2839 circuit board, through-hole solder joints. The damage to the eyelet solder joints of the MC1814 more likely represented infant mortality failures at or very near the time of manufacture, resulting from a marginal design status of this type of solder joint design.

  17. Rapid Prototyping Of Layered Composite Parts

    Science.gov (United States)

    Wolff, Edwin D.

    1992-01-01

    Numerically controlled cutting accelerates fabrication of layers. Proposed method derived from stereoscopic lithography. CATIA or CAEDS computer program used to generate three-dimensional mathematical model of prototype part. In model, geometry of part specified in layers, as in stereoscopic lithography. Model data for each layer fed to computer-numerically-controlled ultrasonic cutting machine. Sheet of prepreg (uncured composite material) of specified layer thickness placed in machine and cut, under control of model data, to specified shape of layer.

  18. A computer generator for randomly layered structures

    Institute of Scientific and Technical Information of China (English)

    YU Jia-shun; HE Zhen-hua

    2004-01-01

    An algorithm is introduced in this paper for the synthesis of randomly layered earth models. Under the assumption that the layering and the physical parameters for a layer are random variables with truncated normal distributions, random numbers sampled from the distributions can be used to construct the layered structure and determine physical parameters for the layers. To demonstrate its application, random models were synthesized for the modelling of seismic ground motion amplification of a site with uncertainties in its model parameters.

  19. Buffer layer for thin film structures

    Science.gov (United States)

    Foltyn, Stephen R.; Jia, Quanxi; Arendt, Paul N.; Wang, Haiyan

    2006-10-31

    A composite structure including a base substrate and a layer of a mixture of strontium titanate and strontium ruthenate is provided. A superconducting article can include a composite structure including an outermost layer of magnesium oxide, a buffer layer of strontium titanate or a mixture of strontium titanate and strontium ruthenate and a top-layer of a superconducting material such as YBCO upon the buffer layer.

  20. [A comment on chiral thin layer chromatography].

    Science.gov (United States)

    Chen, Xuexian; Yuan, Liming

    2016-01-01

    In recent eight years, authors' group has repeated a lot of experiments of chiral thin layer chromatography coming from literature. From the practical opinion, we summarized that there are nine characteristics for chiral thin layer chromatography. Some progresses of chiral thin layer chromatography are reviewed, and the enantioselectivity of a commercial chiral thin layer plate is introduced. The study of vancomycin as the chiral selector in thin layer chromatography is also reported.

  1. Tetradymite layer assisted heteroepitaxial growth and applications

    Energy Technology Data Exchange (ETDEWEB)

    Stoica, Vladimir A.; Endicott, Lynn; Clarke, Roy; Uher, Ctirad

    2017-08-01

    A multilayer stack including a substrate, an active layer, and a tetradymite buffer layer positioned between the substrate and the active layer is disclosed. A method for fabricating a multilayer stack including a substrate, a tetradymite buffer layer and an active layer is also disclosed. Use of such stacks may be in photovoltaics, solar cells, light emitting diodes, and night vision arrays, among other applications.

  2. Chemical solution seed layer for rabits tapes

    Science.gov (United States)

    Goyal, Amit; Paranthaman, Mariappan; Wee, Sung-Hun

    2014-06-10

    A method for making a superconducting article includes the steps of providing a biaxially textured substrate. A seed layer is then deposited. The seed layer includes a double perovskite of the formula A.sub.2B'B''O.sub.6, where A is rare earth or alkaline earth metal and B' and B'' are different rare earth or transition metal cations. A superconductor layer is grown epitaxially such that the superconductor layer is supported by the seed layer.

  3. Spraying asymmetry into functional membranes layer-by-layer

    Science.gov (United States)

    Krogman, Kevin C.; Lowery, Joseph L.; Zacharia, Nicole S.; Rutledge, Gregory C.; Hammond, Paula T.

    2009-06-01

    As engineers strive to mimic the form and function of naturally occurring materials with synthetic alternatives, the challenges and costs of processing often limit creative innovation. Here we describe a powerful yet economical technique for developing multiple coatings of different morphologies and functions within a single textile membrane, enabling scientists to engineer the properties of a material from the nanoscopic level in commercially viable quantities. By simply varying the flow rate of charged species passing through an electrospun material during spray-assisted layer-by-layer deposition, individual fibres within the matrix can be conformally functionalized for ultrahigh-surface-area catalysis, or bridged to form a networked sublayer with complimentary properties. Exemplified here by the creation of selectively reactive gas purification membranes, the myriad applications of this technology also include self-cleaning fabrics, water purification and protein functionalization of scaffolds for tissue engineering.

  4. Polyelectrolyte Layer-by-Layer Assembly on Organic Electrochemical Transistors.

    Science.gov (United States)

    Pappa, Anna-Maria; Inal, Sahika; Roy, Kirsty; Zhang, Yi; Pitsalidis, Charalampos; Hama, Adel; Pas, Jolien; Malliaras, George G; Owens, Roisin M

    2017-03-29

    Oppositely charged polyelectrolyte multilayers (PEMs) were built up in a layer-by-layer (LbL) assembly on top of the conducting polymer channel of an organic electrochemical transistor (OECT), aiming to combine the advantages of well-established PEMs with a high performance electronic transducer. The multilayered film is a model system to investigate the impact of biofunctionalization on the operation of OECTs comprising a poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS) film as the electrically active layer. Understanding the mechanism of ion injection into the channel that is in direct contact with charged polymer films provides useful insights for novel biosensing applications such as nucleic acid sensing. Moreover, LbL is demonstrated to be a versatile electrode modification tool enabling tailored surface features in terms of thickness, softness, roughness, and charge. LbL assemblies built up on top of conducting polymers will aid the design of new bioelectronic platforms for drug delivery, tissue engineering, and medical diagnostics.

  5. Polyelectrolyte Layer-by-Layer Assembly on Organic Electrochemical Transistors

    KAUST Repository

    Pappa, Anna-Maria

    2017-03-06

    Oppositely charged polyelectrolyte multilayers (PEMs) were built up in a layer-by-layer (LbL) assembly on top of the conducting polymer channel of an organic electrochemical transistor (OECT), aiming to combine the advantages of well-established PEMs with a high performance electronic transducer. The multilayered film is a model system to investigate the impact of biofunctionalization on the operation of OECTs comprising a poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS) film as the electrically active layer. Understanding the mechanism of ion injection into the channel that is in direct contact with charged polymer films provides useful insights for novel biosensing applications such as nucleic acid sensing. Moreover, LbL is demonstrated to be a versatile electrode modification tool enabling tailored surface features in terms of thickness, softness, roughness, and charge. LbL assemblies built up on top of conducting polymers will aid the design of new bioelectronic platforms for drug delivery, tissue engineering, and medical diagnostics.

  6. Layer-by-layer microcapsules templated on erythrocyte ghost carriers.

    Science.gov (United States)

    Shaillender, Mutukumaraswamy; Luo, Rongcong; Venkatraman, Subbu S; Neu, Björn

    2011-08-30

    This work reports the fabrication of layer-by-layer (LbL) microcapsules that provide a simple mean for controlling the burst and subsequent release of bioactive agents. Red blood cell (RBC) ghosts were loaded with fluorescently labeled dextran and lysozyme as model compounds via hypotonic dialysis with an encapsulation efficiency of 27-31%. It is demonstrated that these vesicles maintain their shape and integrity and that a uniform distribution of the encapsulated agents within these carriers is achieved. The loaded vesicles were then successfully coated with the biocompatible polyelectrolytes, poly-L-arginine hydrochloride and dextran sulfate. It is demonstrated that the release profiles of the encapsulated molecules can be regulated over a wide range by adjusting the number of polyelectrolyte layers. In addition, the LbL shell also protects the RBC ghost from decomposition thereby potentially preserving the bioactivity of encapsulated drugs or proteins. These microcapsules, consisting of an RBC ghost coated with a polyelectrolyte multilayer, provide a simple mean for the preparation of loaded LbL microcapsules eliminating the core dissolution and post-loading of bioactive agents, which are required for conventional LbL microcapsules.

  7. Fluidized bed layer-by-layer microcapsule formation.

    Science.gov (United States)

    Richardson, Joseph J; Teng, Darwin; Björnmalm, Mattias; Gunawan, Sylvia T; Guo, Junling; Cui, Jiwei; Franks, George V; Caruso, Frank

    2014-08-26

    Polymer microcapsules can be used as bioreactors and artificial cells; however, preparation methods for cell-like microcapsules are typically time-consuming, low yielding, and/or involve custom microfluidics. Here, we introduce a rapid (∼30 min per batch, eight layers), scalable (up to 500 mg of templates), and efficient (98% yield) microcapsule preparation technique utilizing a fluidized bed for the layer-by-layer (LbL) assembly of polymers, and we investigate the parameters that govern the formation of robust capsules. Fluidization in water was possible for particles of comparable diameter to mammalian cells (>5 μm), with the experimental flow rates necessary for fluidization matching well with the theoretical values. Important variables for polymer film deposition and capsule formation were the concentration of polymer solution and the molecular weight of the polymer, while the volume of the polymer solution had a negligible impact. In combination, increasing the polymer molecular weight and polymer solution concentration resulted in improved film deposition and the formation of robust microcapsules. The resultant polymer microcapsules had a thickness of ∼5.5 nm per bilayer, which is in close agreement with conventionally prepared (quiescent (nonflow) adsorption/centrifugation/wash) LbL capsules. The technique reported herein provides a new way to rapidly generate microcapsules (approximately 8 times quicker than the conventional means), while being also amenable to scale-up and mass production.

  8. Nonlinear Instability of Liquid Layers.

    Science.gov (United States)

    Newhouse, Lori Ann

    The nonlinear instability of two superposed viscous liquid layers in planar and axisymmetric configurations is investigated. In the planar configuration, the light layer fluid is bounded below by a wall and above by a heavy semiinfinite fluid. Gravity drives the instability. In the first axisymmetric configuration, the layer is confined between a cylindrical wall and a core of another fluid. In the second, a thread is suspended in an infinite fluid. Surface tension forces drive the instability in the axisymmetric configurations. The nonlinear evolution of the fluid-fluid interface is computed for layers of arbitrary thickness when their dynamics are fully coupled to those of the second fluid. Under the assumption of creeping flow, the flow field is represented by an interfacial distribution of Green's functions. A Fredholm integral equation of the second kind for the strength of the distribution is derived and then solved using an iterative technique. The Green's functions produce flow fields which are periodic in the direction parallel to the wall and have zero velocity on the wall. For small and moderate surface tension, planar layers evolve into a periodic array of viscous plumes which penetrate into the overlying fluid. The morphology of the plumes depends on the surface tension and the ratio of the fluid viscosities. As the viscosity of the layer increases, the plumes change from a well defined drop on top of a narrow stem to a compact column of rising fluid. The capillary instability of cylindrical interfaces and interfaces in which the core thickness varies in the axial direction are investigated. In both the unbounded and wall bounded configurations, the core evolves into a periodic array of elongated fluid drops connected by thin, almost cylindrical fluid links. The characteristics of the drop-link structure depend on the core thickness, the ratio of the core radius to the wall radius, and the ratio of the fluid viscosities. The factors controlling the

  9. Redução da pressão arterial, da IMC e da glicose após treinamento aeróbico em idosas com diabete tipo 2 Decrease in blood pressure, body mass index and glycemia after aerobic training in elderly women with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Luciana Zaranza Monteiro

    2010-10-01

    Full Text Available FUNDAMENTO: O processo de envelhecimento associa-se ao desenvolvimento de várias doenças, que podem ser amenizadas pela prática de atividades físicas. O treinamento aeróbico é um meio efetivo para manter e melhorar as funções cardiovasculares. Além disso, desempenha um papel fundamental na prevenção e tratamento de diversas doenças crônico-degenerativas, em especial o diabete melito. OBJETIVO: Verificar os efeitos de 13 semanas de treinamento aeróbico sobre a pressão arterial, o índice de massa corpórea e a glicemia em idosas com diabete tipo 2. MÉTODOS: Onze mulheres idosas diabéticas (61,0 ± 9,1 anos de idade, sedentárias, realizaram 13 semanas de treinamento aeróbico, compondo o grupo G2. Onze idosas (60,2 ± 6,8 anos de idade controladas não realizaram exercícios físicos durante a pesquisa, constituindo o grupo-controle (G1. O grupo G1 foi submetido somente a orientações educativas uma vez na semana, e o grupo G2, a caminhadas três vezes na semana. RESULTADOS: Houve redução significativa da glicemia e da pressão arterial diastólica nos dois grupos. Não foram encontradas reduções significativas no IMC após o treinamento aeróbico em ambos os grupos. CONCLUSÃO: Treze semanas de treinamento aeróbico foi suficiente para promover reduções significativas na pressão arterial diastólica e glicemia, portanto, esse tipo de exercício reduz os fatores de risco para doenças cardiovasculares e metabólicas.BACKGROUND: The aging process is associated with the development of several diseases, which can be attenuated by the practice of physical activities. Aerobic training is an effective method to maintain and improve cardiovascular function. Additionally, it has a crucial role in the prevention and treatment of several chronic-degenerative diseases, especially diabetes mellitus. }OBJECTIVE: To verify the effect of a 13-week aerobic training program on blood pressure (BP, body mass index (BMI and glycemia levels

  10. Stability of compressible boundary layers

    Science.gov (United States)

    Nayfeh, Ali H.

    1989-01-01

    The stability of compressible 2-D and 3-D boundary layers is reviewed. The stability of 2-D compressible flows differs from that of incompressible flows in two important features: There is more than one mode of instability contributing to the growth of disturbances in supersonic laminar boundary layers and the most unstable first mode wave is 3-D. Whereas viscosity has a destabilizing effect on incompressible flows, it is stabilizing for high supersonic Mach numbers. Whereas cooling stabilizes first mode waves, it destabilizes second mode waves. However, second order waves can be stabilized by suction and favorable pressure gradients. The influence of the nonparallelism on the spatial growth rate of disturbances is evaluated. The growth rate depends on the flow variable as well as the distance from the body. Floquet theory is used to investigate the subharmonic secondary instability.

  11. Photon transport through layered media

    CERN Document Server

    Masood, W

    1999-01-01

    The objective of this project is to study photon transport in layered media. In this regard the properties of the photon have been studied. The interactions that it makes with matter have been studied as well. ANISN code has been run for the sample problems regarding neutron and photon transport. As the project pertains to the transport of photons the layered media, therefore, photon energy spectrum was calculated using isotopes inventory calculation code ORIKAN which is run using 12 energy groups. The photon cross-section library used has a 21 group structure. The 12 group structure was expanded into 21 groups by using the method of histogram splitting. Calculations were made to find values of the energy transmitted at the outermost surface of the shield and then plotted for varying thicknesses of the shield. Finally, the results obtained have been discussed.

  12. Physical Layer Ethernet Clock Synchronization

    Science.gov (United States)

    2010-11-01

    42 nd Annual Precise Time and Time Interval (PTTI) Meeting 77 PHYSICAL LAYER ETHERNET CLOCK SYNCHRONIZATION Reinhard Exel , Georg...5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...Austrian Academy of Sciences Viktor Kaplan StraÃe 2, A-2700 Wiener Neustadt, Austria 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING

  13. Temperature distribution of single layer

    Science.gov (United States)

    Tang, Xuefei; Fan, Zhengxiu; Wang, ZhiJiang

    1993-03-01

    Temperature distributions of Ti02 single layer irradiated by iOns, 1. 06 m wavelength laser pulse were calculated with thermal transfer equation. Following conclusions were obtained: To improve thermal parameters of coating can reduce the peak temperature obviously; The thermal parameters of substrate have little effect on temperature response of coating; Temperature distribution of thin film depends on the electrical field distribution, The peak temperature of quarter -wavelength coatings is lower than that of half-wavelength coatings.

  14. Transition in hypersonic boundary layers

    Science.gov (United States)

    Zhang, Chuanhong; Zhu, Yiding; Chen, Xi; Yuan, Huijing; Wu, Jiezhi; Chen, Shiyi; Lee, Cunbiao; Gad-el-Hak, Mohamed

    2015-10-01

    Transition and turbulence production in a hypersonic boundary layer is investigated in a Mach 6 wind tunnel using Rayleigh-scattering visualization, fast-response pressure measurements, and particle image velocimetry. It is found that the second-mode instability is a key modulator of the transition process. Although the second-mode is primarily an acoustic wave, it causes the formation of high-frequency vortical waves, which triggers a fast transition to turbulence.

  15. Transition in hypersonic boundary layers

    Directory of Open Access Journals (Sweden)

    Chuanhong Zhang

    2015-10-01

    Full Text Available Transition and turbulence production in a hypersonic boundary layer is investigated in a Mach 6 wind tunnel using Rayleigh-scattering visualization, fast-response pressure measurements, and particle image velocimetry. It is found that the second-mode instability is a key modulator of the transition process. Although the second-mode is primarily an acoustic wave, it causes the formation of high-frequency vortical waves, which triggers a fast transition to turbulence.

  16. RBS analysis of electrochromic layers

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.C.; Bell, J.M. [University of Technology, Sydney, NSW (Australia); Kenny, M.J.; Wielunski, L.S. [Commonwealth Scientific and Industrial Research Organisation (CSIRO), Lindfield, NSW (Australia). Div. of Applied Physics

    1993-12-31

    Tungsten oxide thin films produced by dip-coating from tungsten alkoxide solutions are of interest for their application in large area switchable windows. The application consists of a layer of electrochromic tungsten oxide (W0{sub 3}) on indium tin oxide (ITO) coated glass in contact with a complementary structure. Electrochromic devices are switchable between states of high and low transparency by the application of a small voltage. The mechanism relies on the dual injection of ions and electrons into the W0{sub 3} layer from adjacent layers in the device. Electrochromic tungsten oxide can be deposited using standard techniques (eg. sputtering and evaporation) but also using sol-gel deposition. Sol-gel processing has an advantage over conventional preparation techniques because of the simplicity of the equipment. The scaling up to large area coatings is also feasible. RBS and forward recoil has been used to obtain profiles for individual elements in the structure of electrochromic films. 3 refs., 3 figs.

  17. Spectral and gravimetric analysis of completely oxidized amalgam systems.

    Science.gov (United States)

    Mueller, H J

    1980-01-01

    Analysis of the soluble solution species, insoluble solution precipitate, adherent corrosion products, and microstructural changes of the substrate amalgam after selected polarization to -0.2v and +0.5v in a chloride solution is reported. Results indicate only small concentrations of soluble species, high concentrations of a Sn insoluble solution precipitate at -0.2v, and high concentrations of a Cu precipitate at +0.5v, related to CuCl2 . 3 Cu (OH)2. The completely oxidized amalgam microstructure indicates a thin outermost layer of predominantly Sn--Cl, a thick corroded layer of Ag-Sn-Hg-Cl, and the remaining substrate amalgam. The compound of (SnO) 160 is also associated with the thick corroded layer. The microstructure of the substrate amalgam exhibits, besides the normally occurring phases and products, four new phases or alterations due to the redistribution of Sn, Cl and 0 from the gamma-2 corrosion products, (1) the reappearance of voids, (2) a grey Ag-Sn-Cl phase with and without Cu localized at specific sites in the gamma-1 matrix, (3) dark areas or partially filled voids containing the same elements as in (2) and formerly occupied by the gamma-2 products, and (4) a Cu-rich phase from the deterioration of the Cu6Sn5 phase and also included within the matrix. These changes, particularly (1), (2) and (3) occur with the onset of the gamma-1 deterioration. Unreacted Ag3Sn including the additions of the Cu3Sn component is the last phase to be attacked in the composite amalgam.

  18. Cross-layer design in optical networks

    CERN Document Server

    Brandt-Pearce, Maïté; Demeester, Piet; Saradhi, Chava

    2013-01-01

    Optical networks have become an integral part of the communications infrastructure needed to support society’s demand for high-speed connectivity.  Cross-Layer Design in Optical Networks addresses topics in optical network design and analysis with a focus on physical-layer impairment awareness and network layer service requirements, essential for the implementation and management of robust scalable networks.  The cross-layer treatment includes bottom-up impacts of the physical and lambda layers, such as dispersion, noise, nonlinearity, crosstalk, dense wavelength packing, and wavelength line rates, as well as top-down approaches to handle physical-layer impairments and service requirements.

  19. Layers over layer-by-layer assemblies: silanization of polyelectrolyte multilayers.

    Science.gov (United States)

    Dirani, Ali; Fernandes, Antony E; Wong, Diana Ramirez; Lipnik, Pascale; Poleunis, Claude; Nysten, Bernard; Glinel, Karine; Jonas, Alain M

    2014-08-26

    The functionalization of poly(allylamine hydrochloride)/poly(acrylic acid) (PAH/PAA) polyelectrolyte multilayers by silanes reacted from the gas phase is studied depending on reaction time and temperature, pH of multilayer assembly, and nature of the reacting silane group. Whereas monochlorosilanes only diffuse in the multilayer and graft in limited amount, trichloro- and triethoxysilanes form rapidly a continuous gel layer on the surface of the multilayer, with a thickness of ca. 10-20 nm. The reactivity is lower in the strongly paired regime of the multilayers (neutral assembly conditions) but otherwise is not affected by the pH of multilayer assembly. Silanization considerably broadens the range of possible functionalities for (PAH/PAA) multilayers: hydrophobicity, surface-initiated polymerization, and grafting of fluorescent probes by the formation of disulfide bridges are demonstrated. Conversely, our results also broaden the range of substrates that can be functionalized by silanes, using (PAH/PAA) multilayers as ubiquitous anchoring layers.

  20. Sparse coding for layered neural networks

    Science.gov (United States)

    Katayama, Katsuki; Sakata, Yasuo; Horiguchi, Tsuyoshi

    2002-07-01

    We investigate storage capacity of two types of fully connected layered neural networks with sparse coding when binary patterns are embedded into the networks by a Hebbian learning rule. One of them is a layered network, in which a transfer function of even layers is different from that of odd layers. The other is a layered network with intra-layer connections, in which the transfer function of inter-layer is different from that of intra-layer, and inter-layered neurons and intra-layered neurons are updated alternately. We derive recursion relations for order parameters by means of the signal-to-noise ratio method, and then apply the self-control threshold method proposed by Dominguez and Bollé to both layered networks with monotonic transfer functions. We find that a critical value αC of storage capacity is about 0.11|a ln a| -1 ( a≪1) for both layered networks, where a is a neuronal activity. It turns out that the basin of attraction is larger for both layered networks when the self-control threshold method is applied.

  1. Hydraulic Stability of Single-Layer Dolos and Accropode Armour Layers

    DEFF Research Database (Denmark)

    Christensen, M.; Burcharth, H. F.

    1995-01-01

    A new design for Dolos breakwater armour layers is presented: Dolos armour units are placed in a selected geometric pattern in a single layer. A series of model tests have been performed in order to determine the stability of such single-layer Dolos armour layers. The test results are presented...... and compared to the stability formula for the traditional double-layer, randomly placed Dolos armour layer design presented by Burcharth (1992). The results of a series of stability tests performed with Accropode® armour layers is presented and compared to the test results obtained with single-layer Dolos...

  2. Layer-by-layer assemblies for antibacterial applications.

    Science.gov (United States)

    Zhu, Xiaoying; Jun Loh, Xian

    2015-12-01

    The adhesion and proliferation of bacteria on various artificial surfaces affects the functionality of these specific interfaces. To overcome the problems caused by bacterial growth on these surfaces, various antibacterial coatings were developed. In this review, we summarized most of the antibacterial surfaces prepared by the Layer-by-Layer (LbL) assembly approach and classified these LbL films based on their antibacterial mechanisms. In the first group, the bactericidal LbL assemblies which incorporate various biocides including heavy metals, antibiotics, cationic molecules, antimicrobial peptides and enzymes are able to kill surrounding or contacted bacteria. In the second group, we focused on the physical aspects of film surfaces. Bacterial adhesion resistant LbL films have been fabricated to adjust the substrate surface properties such as surface free energy (or wettability), roughness, and surface charge which may affect the adhesion of bacteria. Furthermore, as an enhancement in the antibacterial efficiency, multifunctional LbL assemblies combining both bactericidal and adhesion resistant functionalities were discussed. The advantages and limitations of these antibacterial LbL assemblies were summarized and subsequently directions for future development were proposed.

  3. Dendrimers in Layer-by-Layer Assemblies: Synthesis and Applications

    Directory of Open Access Journals (Sweden)

    Katsuhiko Sato

    2013-07-01

    Full Text Available We review the synthesis of dendrimer-containing layer-by-layer (LbL assemblies and their applications, including biosensing, controlled drug release, and bio-imaging. Dendrimers can be built into LbL films and microcapsules by alternating deposition of dendrimers and counter polymers on the surface of flat substrates and colloidal microparticles through electrostatic bonding, hydrogen bonding, covalent bonding, and biological affinity. Dendrimer-containing LbL assemblies have been used to construct biosensors, in which electron transfer mediators and metal nanoparticles are often coupled with dendrimers. Enzymes have been successfully immobilized on the surface of electrochemical and optical transducers by forming enzyme/dendrimer LbL multilayers. In this way, high-performance enzyme sensors are fabricated. In addition, dendrimer LbL films and microcapsules are useful for constructing drug delivery systems because dendrimers bind drugs to form inclusion complexes or the dendrimer surface is covalently modified with drugs. Magnetic resonance imaging of cancer cells by iron oxide nanoparticles coated with dendrimer LbL film is also discussed.

  4. Method for producing substrates for superconducting layers

    DEFF Research Database (Denmark)

    2013-01-01

    There is provided a method for producing a substrate (600) suitable for supporting an elongated superconducting element, wherein, e.g., a deformation process is utilized in order to form disruptive strips in a layered solid element, and where etching is used to form undercut volumes (330, 332......) between an upper layer (316) and a lower layer (303) of the layered solid element. Such relatively simple steps enable providing a substrate which may be turned into a superconducting structure, such as a superconducting tape, having reduced AC losses, since the undercut volumes (330, 332) may be useful...... for separating layers of material. In a further embodiment, there is placed a superconducting layer on top of the upper layer (316) and/or lower layer (303), so as to provide a superconducting structure with reduced AC losses....

  5. Black layers on historical architecture.

    Science.gov (United States)

    Toniolo, Lucia; Zerbi, Carlotta M; Bugini, Roberto

    2009-03-01

    The external surface of any building in urban polluted environment is unavoidably destined to be covered with layers that assume a grey to black colour and are generally called 'black crusts'. These, according to standard protocols and glossary, are deteriorated surface layers of stone material; they can have variable thickness, are hard and fragile and can detach spontaneously from the substrate, which, in general, is quite decayed. Plain visual examination may lead to consider 'black crusts' all similar, whilst only a careful diagnostic investigation can distinguish 'black crusts' and the consequences of their formation on stone substrates. In this paper, various black layers on marble are studied and compared and the morphological and compositional characteristics discussed according to the related mechanisms of formation. Differences between old (hundred years) and recent crusts (30 years) are investigated and pointed out. Samples of black crusts collected from the Milan Cathedral façade (Candoglia Marble) have been studied and compared with the careful and synergic employ of traditional techniques: optical (transmission and reflected VIS light) and electron microscopy, X-ray spectrometry and micro-Fourier transform infrared spectroscopy. Visual examination of loose fragments does not allow to point out outstanding differences amongst the various samples; black layers have similar main mineral components, gypsum and airborne particles, with different spatial distribution. The microscopic studies allowed to point out the porosity differences, the gypsum crystallisation habit, different amount of embedded particles, level and progress of marble decay. The observations lead to define three main types of black crusts: black crust deriving from marble sulphation, compact deposit and encrustation due to exogenic materials deposition. Black crusts show evidence of sulphation in progress, without a clear continuity solution between crust and marble; the lack of

  6. Reverse engineering of multi-layer films

    OpenAIRE

    Effendi Widjaja; Marc Garland

    2011-01-01

    This contribution introduces the combined application of Raman microscopy and band-target entropy minimization (BTEM) in order to successfully reverse-engineer a multi-layer packaging material. Three layers are identified, namely, polyethylene, a paper and talc layer (with two distinct cellulose forms), and a poly-styrene co-polymer composite containing anatase and calcite. This rapid and non-destructive approach provides a unique opportunity for the assessment of multi-layer composites, incl...

  7. Assembly of 1D nanofibers into a 2D bi-layered composite nanofibrous film with different functionalities at the two layers via layer-by-layer electrospinning.

    Science.gov (United States)

    Wang, Zijiao; Ma, Qianli; Dong, Xiangting; Li, Dan; Xi, Xue; Yu, Wensheng; Wang, Jinxian; Liu, Guixia

    2016-12-21

    A two-dimensional (2D) bi-layered composite nanofibrous film assembled by one-dimensional (1D) nanofibers with trifunctionality of electrical conduction, magnetism and photoluminescence has been successfully fabricated by layer-by-layer electrospinning. The composite film consists of a polyaniline (PANI)/Fe3O4 nanoparticle (NP)/polyacrylonitrile (PAN) tuned electrical-magnetic bifunctional layer on one side and a Tb(TTA)3(TPPO)2/polyvinylpyrrolidone (PVP) photoluminescent layer on the other side, and the two layers are tightly combined face-to-face together into the novel bi-layered composite film of trifunctionality. The brand-new film has totally different characteristics at the double layers. The electrical conductivity and magnetism of the electrical-magnetic bifunctional layer can be, respectively, tunable via modulating the PANI and Fe3O4 NP contents, and the highest electrical conductivity can reach up to the order of 10(-2) S cm(-1), and predominant intense green emission at 545 nm is obviously observed in the photoluminescent layer under the excitation of 357 nm single-wavelength ultraviolet light. More importantly, the luminescence intensity of the photoluminescent layer remains almost unaffected by the electrical-magnetic bifunctional layer because the photoluminescent materials have been successfully isolated from dark-colored PANI and Fe3O4 NPs. By comparing with the counterpart single-layered composite nanofibrous film, it is found that the bi-layered composite nanofibrous film has better performance. The novel bi-layered composite nanofibrous film with trifunctionality has potential in the fields of nanodevices, molecular electronics and biomedicine. Furthermore, the design conception and fabrication technique for the bi-layered multifunctional film provide a new and facile strategy towards other films of multifunctionality.

  8. S-layer nanoglycobiology of bacteria

    OpenAIRE

    Messner, Paul; Steiner, Kerstin; Zarschler, Kristof; Schäffer, Christina

    2008-01-01

    Cell surface layers (S-layers) are common structures of the bacterial cell envelope with a lattice-like appearance that are formed by a self-assembly process. Frequently, the constituting S-layer proteins are modified with covalently linked glycan chains facing the extracellular environment. S-layer glycoproteins from organisms of the Bacillaceae family possess long, O-glycosidically linked glycans that are composed of a great variety of sugar constituents. The observed variations already exc...

  9. Multiple-Dynode-Layer Microchannel Plate

    Science.gov (United States)

    Woodgate, Bruce E.

    1990-01-01

    Improved microchannel-plate electron image amplifier made of stack of discrete microchannel-plate layers. New plates easier to manufacture because no need to etch long, narrow holes, to draw and bundle thin glass tubes, or to shear plates to give microchannels curvatures necessary for reduction of undesired emission of ions. Discrete dynode layers stacked with slight offset from layer to layer to form microchannel plate with curved channels. Provides for relatively fast recharging of microchannel dynodes, with consequent enhancement of performance.

  10. Behavior of macromolecules in adsorbed layers

    Institute of Scientific and Technical Information of China (English)

    牟伯中[1; 姚恒申[2; 罗平亚[3

    2000-01-01

    A model for describing the behavior ot macromoiecuies in aosoroea layers is developed by introducing a concept of distribution density of layer thickness U based on stochastic process and probabilistic statistics. The molecular behavior of layers adsorbed on clay particle surfaces is discussed; the random distribution and its statistics of the layer thickness are given by incorporating experimental results with an ionic polyelectrolyte with the molecular weight of 1.08×106and chain charged density of 0.254.

  11. Behavior of macromolecules in adsorbed layers

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A model for describing the behavior of macromolecules in adsorbed layers is developed by introducing a concept of distribution density of layer thickness U based on stochastic process and probabilistic statistics. The molecular behavior of layers adsorbed on clay particle surfaces is discussed; the random distribution and its statistics of the layer thickness are given by incorporating experimental results with an ionic polyelectrolyte with the molecular weight of 1.08×106 and chain charged density of 0.254.

  12. Multi-Layer Traffic Steering

    DEFF Research Database (Denmark)

    Fotiadis, Panagiotis; Polignano, Michele; Gimenez, Lucas Chavarria

    2013-01-01

    This paper investigates the potentials of traffic steering in the Radio Resource Control (RRC) Idle state by evaluating the Absolute Priorities (AP) framework in a multilayer Long Term Evolution (LTE) macrocell scenario. Frequency priorities are broadcast on the system information and RRC Idle...... users can be steered towards higher priority carriers whenever coverage allows it. However, such an approach may overload the prioritized layers. For that purpose, an enhanced scheme is proposed, where priorities are adjusted on a user basis and are provided to the terminal via the connection release...

  13. Computer Program Re-layers Engineering Drawings

    Science.gov (United States)

    Crosby, Dewey C., III

    1990-01-01

    RULCHK computer program aids in structuring layers of information pertaining to part or assembly designed with software described in article "Software for Drawing Design Details Concurrently" (MFS-28444). Checks and optionally updates structure of layers for part. Enables designer to construct model and annotate its documentation without burden of manually layering part to conform to standards at design time.

  14. The Hole in the Ozone Layer.

    Science.gov (United States)

    Hamers, Jeanne S.; Jacob, Anthony T.

    This document contains information on the hole in the ozone layer. Topics discussed include properties of ozone, ozone in the atmosphere, chlorofluorocarbons, stratospheric ozone depletion, effects of ozone depletion on life, regulation of substances that deplete the ozone layer, alternatives to CFCs and Halons, and the future of the ozone layer.…

  15. Separating a Walkable Environment into Layers

    NARCIS (Netherlands)

    Hillebrand, A.; van den Akker, J.M.; Geraerts, R.J.; Hoogeveen, J.A.

    2016-01-01

    A multi-layered environment is a representation of the walkable environment in a 3D virtual environment that comprises a set of two-dimensional layers together with the locations where the different layers touch, which are called connections. This representation can be used for crowd simulations, e.

  16. An Electromagnetic GL Double Layered Cloak

    CERN Document Server

    Xie, Ganquan; Xie, Feng; Xie, Lee

    2009-01-01

    In this paper, we propose a new electromagnetic (EM) GL double layered cloak. The GL double layered cloak is consist of two sphere annular layers, $R_1 \\le r \\le R_2$ and $R_2 \\le r \\le R_3$. Two type cloak materials are proposed and installed in the each layer, respectively. The outer layer cloak of the GL double layered cloak has the invisible function, the inner layer cloak has fully absorption function. The GL double layered metamaterials are weak degenerative and weak dispersive. When the source is located outside of the GL double layered cloak, the excited EM wave field propagation outside of the double layered cloak is as same as in free space and never be disturbed by the cloak; also, the exterior EM wave can not penetrate into the inner layer and concealment. When local sources are located inside of the GL double cloaked concealment with the normal EM materials, the excited EM wave is propagating under Maxwell equation governing, it is complete absorbed by the inner layer cloak of GL double cloak and...

  17. Dispersal, settling and layer formation.

    Science.gov (United States)

    Caffrey, James R; Hughes, Barry D; Landman, Kerry A

    2011-07-01

    Motivated by examples in developmental biology and ecology, we develop a model for convection-dominated invasion of a spatial region by initially motile agents which are able to settle permanently. The motion of the motile agents and their rate of settling are affected by the local concentration of settled agents. The model can be formulated as a nonlinear partial differential equation for the time-integrated local concentration of the motile agents, from which the instantaneous density of settled agents and its long-time limit can be extracted. In the limit of zero diffusivity, the partial differential equation is of first order; for application-relevant initial and boundary-value problems, shocks arise in the time-integrated motile agent density, leading to delta-function components in the motile agent density. Furthermore, there are simple solutions for a model of successive layer formation. In addition some analytic results for a one-dimensional system with non-zero diffusivity can also be obtained. A case study, both with and without diffusion, is examined numerically. Some important predictions of the model are insensitive to the specific settling law used and the model offers insight into biological processes involving layered growth or overlapping generations of colonization.

  18. Layered Working-Set Trees

    CERN Document Server

    Bose, Prosenjit; Dujmović, Vida; Howat, John

    2009-01-01

    The working-set bound [Sleator and Tarjan, J. ACM, 1985] roughly states that searching for an element is fast if the element was accessed recently. Binary search trees, such as splay trees, can achieve this property in the amortized sense, while data structures that are not binary search trees are known to have this property in the worst case. We close this gap and present a binary search tree called a layered working-set tree that guarantees the working-set property in the worst case. The unified bound [Badoiu et al., TCS, 2007] roughly states that searching for an element is fast if it is near (in terms of rank distance) to a recently accessed element. We show how layered working-set trees can be used to achieve the unified bound to within a small additive term in the amortized sense while maintaining in the worst case an access time that is both logarithmic and within a small multiplicative factor of the working-set bound.

  19. Textured strontium titanate layers on platinum by atomic layer deposition

    Energy Technology Data Exchange (ETDEWEB)

    Blomberg, T., E-mail: tom.blomberg@asm.com [ASM Microchemistry Ltd., Vaeinoe Auerin katu 12 A, 00560 Helsinki (Finland); Anttila, J.; Haukka, S.; Tuominen, M. [ASM Microchemistry Ltd., Vaeinoe Auerin katu 12 A, 00560 Helsinki (Finland); Lukosius, M.; Wenger, Ch. [IHP, Im Technologiepark 25, 15236 Frankfurt (Oder) (Germany); Saukkonen, T. [Aalto University, Puumiehenkuja 3, 02150 Espoo (Finland)

    2012-08-31

    Formation of textured strontium titanate (STO) layers with large lateral grain size (0.2-1 {mu}m) and low X-ray reflectivity roughness ({approx} 1.36 nm) on Pt electrodes by industry proven atomic layer deposition (ALD) method is demonstrated. Sr(t-Bu{sub 3}Cp){sub 2}, Ti(OMe){sub 4} and O{sub 3} precursors at 250 Degree-Sign C were used to deposit Sr rich STO on Pt/Ti/SiO{sub 2}/Si Empty-Set 200 mm substrates. After crystallization post deposition annealing at 600 Degree-Sign C in air, most of the STO grains showed a preferential orientation of the {l_brace}001{r_brace} plane parallel to the substrate surface, although other orientations were also present. Cross sectional and plan view transmission electron microscopy and electron diffraction analysis revealed more than an order of magnitude larger lateral grain sizes for the STO compared to the underlying multicrystalline {l_brace}111{r_brace} oriented platinum electrode. The combination of platinum bottom electrodes with ALD STO(O{sub 3}) shows a promising path towards the formation of single oriented STO film. - Highlights: Black-Right-Pointing-Pointer Amorphous strontium titanate (STO) on platinum formed a textured film after annealing. Black-Right-Pointing-Pointer Single crystal domains in 60 nm STO film were 0.2-1 {mu}m wide. Black-Right-Pointing-Pointer Most STO grains were {l_brace}001{r_brace} oriented.

  20. Aligned Layers of Silver Nano-Fibers

    Directory of Open Access Journals (Sweden)

    Andrii B. Golovin

    2012-02-01

    Full Text Available We describe a new dichroic polarizers made by ordering silver nano-fibers to aligned layers. The aligned layers consist of nano-fibers and self-assembled molecular aggregates of lyotropic liquid crystals. Unidirectional alignment of the layers is achieved by means of mechanical shearing. Aligned layers of silver nano-fibers are partially transparent to a linearly polarized electromagnetic radiation. The unidirectional alignment and density of the silver nano-fibers determine degree of polarization of transmitted light. The aligned layers of silver nano-fibers might be used in optics, microwave applications, and organic electronics.

  1. Dense, layered membranes for hydrogen separation

    Science.gov (United States)

    Roark, Shane E.; MacKay, Richard; Mundschau, Michael V.

    2006-02-21

    This invention provides hydrogen-permeable membranes for separation of hydrogen from hydrogen-containing gases. The membranes are multi-layer having a central hydrogen-permeable layer with one or more catalyst layers, barrier layers, and/or protective layers. The invention also relates to membrane reactors employing the hydrogen-permeable membranes of the invention and to methods for separation of hydrogen from a hydrogen-containing gas using the membranes and reactors. The reactors of this invention can be combined with additional reactor systems for direct use of the separated hydrogen.

  2. Five layers in a turbulent pipe flow

    Science.gov (United States)

    Lee, Jinyoung; Ahn, Junsun; Sung, Hyung Jin

    2016-11-01

    The scaling laws governing the five layers of the mean velocity distribution of a turbulent pipe flow were characterized using the available DNS data (Reτ = 544 , 934, 3008). Excluding the very near-wall and core regions, the buffer, meso- and log layers were identified by examining the streamwise mean momentum equation and the net force spectra. The (outer) log layer was located in the overlap region where the viscous force was negligible. Another (inner) log layer was observed in the buffer layer, in which the viscous force was directly counterbalanced by the turbulent inertia. A meso-layer between the buffer and outer log layers was found to feature viscous effects. The acceleration force of the large-scale motions (LSMs) penetrated the outer log layer at higher Reynolds numbers, as observed in the net force spectra. The acceleration force of the LSMs became strong and was counterbalanced by the deceleration force of the small-scale motions (SSMs), indicating that the inner and outer length scales contributed equally to the meso-layer. The outer log layer was established by forming an extended connection link between the meso- and outer layers. This work was supported by the Creative Research Initiatives (No. 2016-004749) program of the National Research Foundation of Korea (MSIP) and partially supported by KISTI under the Strategic Supercomputing Support Program.

  3. Experimental research on the stability of armour and secondary layer in a single layered Tetrapod breakwater

    NARCIS (Netherlands)

    De Jong, W.; Verhagen, H.J.; Olthof, J.

    2004-01-01

    Physical model tests were done on an armour of Tetrapods, placed in a single layer. The objective of the investigations was to study the stability of the secondary layer, and to see if the material of this secondary layer could be washed out through the single layer of Tetrapods. It was concluded

  4. Combined technique for estimating the quality of joining the layers in three-layer pipes

    Science.gov (United States)

    Nikulin, S. A.; Rozhnov, A. B.; Nechaikina, T. A.; Rogachev, S. O.; Votinov, S. N.; Zavodchikov, S. Yu.

    2014-04-01

    The prospects of estimating the quality of joining the layers of a three-layer pipe for the fuel claddings of a fast reactor from the results of a combined investigation, which includes computer-assisted quantitative metallography, microindentation, electron-probe microanalysis, and layer-by-layer atomic emission spectroscopy, are discussed.

  5. Multi-layered proton-conducting electrolyte

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tae H.; Dorris, Stephen E.; Balachandran, Uthamalingam

    2017-06-27

    The present invention provides a multilayer anode/electrolyte assembly comprising a porous anode substrate and a layered solid electrolyte in contact therewith. The layered solid electrolyte includes a first dense layer of yttrium-doped barium zirconate (BZY), optionally including another metal besides Y, Ba, and Zr (e.g., a lanthanide metal such as Pr) on one surface thereof, a second dense layer of yttrium-doped barium cerate (BCY), and an interfacial layer between and contacting the BZY and BCY layers. The interfacial layer comprises a solid solution of the BZY and BCY electrolytes. The porous anode substrate comprises at least one porous ceramic material that is stable to carbon dioxide and water (e.g., porous BZY), as well as an electrically conductive metal and/or metal oxide (e.g., Ni, NiO, and the like).

  6. Reflective article having a sacrificial cathodic layer

    Energy Technology Data Exchange (ETDEWEB)

    Kabagambe, Benjamin; Buchanan, Michael J.; Scott, Matthew S.; Rearick, Brian K.; Medwick, Paul A.; McCamy, James W.

    2017-09-12

    The present invention relates to reflective articles, such as solar mirrors, that include a sacrificial cathodic layer. The reflective article, more particularly includes a substrate, such as glass, having a multi-layered coating thereon that includes a lead-free sacrificial cathodic layer. The sacrificial cathodic layer includes at least one transition metal, such as a particulate transition metal, which can be in the form of flakes (e.g., zinc flakes). The sacrificial cathodic layer can include an inorganic matrix formed from one or more organo-titanates. Alternatively, the sacrificial cathodic layer can include an organic polymer matrix (e.g., a crosslinked organic polymer matrix formed from an organic polymer and an aminoplast crosslinking agent). The reflective article also includes an outer organic polymer coating, that can be electrodeposited over the sacrificial cathodic layer.

  7. S-layer protein self-assembly.

    Science.gov (United States)

    Pum, Dietmar; Toca-Herrera, Jose Luis; Sleytr, Uwe B

    2013-01-25

    Crystalline S(urface)-layers are the most commonly observed cell surface structures in prokaryotic organisms (bacteria and archaea). S-layers are highly porous protein meshworks with unit cell sizes in the range of 3 to 30 nm, and thicknesses of ~10 nm. One of the key features of S-layer proteins is their intrinsic capability to form self-assembled mono- or double layers in solution, and at interfaces. Basic research on S-layer proteins laid foundation to make use of the unique self-assembly properties of native and, in particular, genetically functionalized S-layer protein lattices, in a broad range of applications in the life and non-life sciences. This contribution briefly summarizes the knowledge about structure, genetics, chemistry, morphogenesis, and function of S-layer proteins and pays particular attention to the self-assembly in solution, and at differently functionalized solid supports.

  8. Network Composition from Multi-layer Data

    CERN Document Server

    Lerman, Kristina; Yan, Xiaoran

    2016-01-01

    It is common for people to access multiple social networks, for example, using phone, email, and social media. Together, the multi-layer social interactions form a "integrated social network." How can we extend well developed knowledge about single-layer networks, including vertex centrality and community structure, to such heterogeneous structures? In this paper, we approach these challenges by proposing a principled framework of network composition based on a unified dynamical process. Mathematically, we consider the following abstract problem: Given multi-layer network data and additional parameters for intra and inter-layer dynamics, construct a (single) weighted network that best integrates the joint process. We use transformations of dynamics to unify heterogeneous layers under a common dynamics. For inter-layer compositions, we will consider several cases as the inter-layer dynamics plays different roles in various social or technological networks. Empirically, we provide examples to highlight the usef...

  9. A new layered iron fluorophosphate

    Indian Academy of Sciences (India)

    Amitava Choudhury

    2002-04-01

    A new iron fluorophosphate of the composition, [C6N4H21] [Fe2F2(HPO4)3][H2PO4]·2H2O, I has been prepared by the hydrothermal route. This compound contains iron fluorophosphate layers and the H2PO$_{4}^{-}$ anions are present in the interlayer space along with the protonated amine and water molecules. The compound crystallizes in the monoclinic space group 21/. ( = 13.4422(10) Å, = 9.7320(10) Å, = 18.3123(3) Å, = 92.1480 °, = 2393.92(5) Å3, = 4, = 719.92, calc = 1.997 g cm-3, 1 = 0.03 and 2 = 0.09).

  10. Smear layer--materials surface.

    Science.gov (United States)

    Eick, J D

    1992-01-01

    SEM and TEM photomicrographs were presented of the smear layer and several dentin-adhesive interfaces. It was shown that as the wetting and penetration of the dentin adhesive increased, the shear bond strength also increased. Three categories of dentin adhesives were presented. Category one included Scotchbond, Dentin Adhesit and Gluma, with shear bond strength values between 5 and 7 MPa; the second category, dentin adhesives based on Dr. Bowen's research, included Tenure and Mirage Bond, with shear bond strengths between 8 and 14 MPa; the third category included Superbond and Scotchbond 2, with shear bond strength values up to 20 MPa. Failures occurred at the interface or in the resin adhesive for materials in categories one and two; failures occurred through the dentin or composite for materials in category three.

  11. films using atomic layer deposition

    Science.gov (United States)

    Chervinskii, Semen; Matikainen, Antti; Dergachev, Alexey; Lipovskii, Andrey A.; Honkanen, Seppo

    2014-08-01

    We fabricated self-assembled silver nanoisland films using a recently developed technique based on out-diffusion of silver from an ion-exchanged glass substrate in reducing atmosphere. We demonstrate that the position of the surface plasmon resonance of the films depends on the conditions of the film growth. The resonance can be gradually shifted up to 100 nm towards longer wavelengths by using atomic layer deposition of titania, from 3 to 100 nm in thickness, upon the film. Examination of the nanoisland films in surface-enhanced Raman spectrometry showed that, in spite of a drop of the surface-enhanced Raman spectroscopy (SERS) signal after the titania spacer deposition, the Raman signal can be observed with spacers up to 7 nm in thickness. Denser nanoisland films show slower decay of the SERS signal with the increase in spacer thickness.

  12. NDAS Hardware Translation Layer Development

    Science.gov (United States)

    Nazaretian, Ryan N.; Holladay, Wendy T.

    2011-01-01

    The NASA Data Acquisition System (NDAS) project is aimed to replace all DAS software for NASA s Rocket Testing Facilities. There must be a software-hardware translation layer so the software can properly talk to the hardware. Since the hardware from each test stand varies, drivers for each stand have to be made. These drivers will act more like plugins for the software. If the software is being used in E3, then the software should point to the E3 driver package. If the software is being used at B2, then the software should point to the B2 driver package. The driver packages should also be filled with hardware drivers that are universal to the DAS system. For example, since A1, A2, and B2 all use the Preston 8300AU signal conditioners, then the driver for those three stands should be the same and updated collectively.

  13. Superconductivity in Layered Organic Metals

    Directory of Open Access Journals (Sweden)

    Jochen Wosnitza

    2012-04-01

    Full Text Available In this short review, I will give an overview on the current understanding of the superconductivity in quasi-two-dimensional organic metals. Thereby, I will focus on charge-transfer salts based on bis(ethylenedithiotetrathiafulvalene (BEDT-TTF or ET for short. In these materials, strong electronic correlations are clearly evident, resulting in unique phase diagrams. The layered crystallographic structure leads to highly anisotropic electronic as well as superconducting properties. The corresponding very high orbital critical field for in-plane magnetic-field alignment allows for the occurrence of the Fulde–Ferrell– Larkin–Ovchinnikov state as evidenced by thermodynamic measurements. The experimental picture on the nature of the superconducting state is still controversial with evidence both for unconventional as well as for BCS-like superconductivity.

  14. Tracer diffusion inside fibrinogen layers

    Science.gov (United States)

    Cieśla, Michał; Gudowska-Nowak, Ewa; Sagués, Francesc; Sokolov, Igor M.

    2014-01-01

    We investigate the obstructed motion of tracer (test) particles in crowded environments by carrying simulations of two-dimensional Gaussian random walk in model fibrinogen monolayers of different orientational ordering. The fibrinogen molecules are significantly anisotropic and therefore they can form structures where orientational ordering, similar to the one observed in nematic liquid crystals, appears. The work focuses on the dependence between level of the orientational order (degree of environmental crowding) of fibrinogen molecules inside a layer and non-Fickian character of the diffusion process of spherical tracer particles moving within the domain. It is shown that in general particles motion is subdiffusive and strongly anisotropic, and its characteristic features significantly change with the orientational order parameter, concentration of fibrinogens, and radius of a diffusing probe.

  15. Tracer diffusion inside fibrinogen layers

    CERN Document Server

    Cieśla, Michał; Sagués, Francesc; Sokolov, Igor M

    2013-01-01

    We investigate the motion of tracer (test) particles in crowded environments by carrying simulations of two-dimensional Gaussian random walk in model fibrinogen monolayers of different orientational ordering. The fibrinogen molecules are significantly anisotropic and therefore they can form structures where orientational ordering, similar to the one observed in nematic liquid crystals, appears. The work focuses on the dependence between level of the orientational order (degree of environmental crowding) of fibrinogen molecules inside a layer and non-Fickian character of the diffusion process of spherical tracer particles moving within the domain. It is shown that in general particles motion is subdiffusive and strongly anisotropic, and its characteristic features significantly change with the orientational order parameter, concentration of fibrinogens and radius of a diffusing probe.

  16. Layer-by-layer growth of GaN induced by silicon

    Energy Technology Data Exchange (ETDEWEB)

    Munkholm, A. [Chemistry Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Thompson, Carol [Department of Physics, Northern Illinois University, DeKalb, Illinois 60115 (United States); Ramana Murty, M. V. [Materials Science Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Eastman, J. A. [Materials Science Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Auciello, O. [Materials Science Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Stephenson, G. B. [Materials Science Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Fini, P. [Materials Department, University of California, Santa Barbara, California 93106 (United States); DenBaars, S. P. [Materials Department, University of California, Santa Barbara, California 93106 (United States); Speck, J. S. [Materials Department, University of California, Santa Barbara, California 93106 (United States)

    2000-09-11

    We present in situ x-ray scattering studies of surface morphology evolution during metal-organic chemical vapor deposition of GaN. Dosing the GaN(0001) surface with Si is shown to change the growth mode from step-flow to layer-by-layer over a wide temperature range. Annealing of highly doped layers causes Si to segregate to the surface, which also induces layer-by-layer growth. (c) 2000 American Institute of Physics.

  17. Inter-layer synchronization in non-identical multi-layer networks.

    Science.gov (United States)

    Leyva, I; Sevilla-Escoboza, R; Sendiña-Nadal, I; Gutiérrez, R; Buldú, J M; Boccaletti, S

    2017-04-04

    Inter-layer synchronization is a dynamical process occurring in multi-layer networks composed of identical nodes. This process emerges when all layers are synchronized, while nodes in each layer do not necessarily evolve in unison. So far, the study of such inter-layer synchronization has been restricted to the case in which all layers have an identical connectivity structure. When layers are not identical, the inter-layer synchronous state is no longer a stable solution of the system. Nevertheless, when layers differ in just a few links, an approximate treatment is still feasible, and allows one to gather information on whether and how the system may wander around an inter-layer synchronous configuration. We report the details of an approximate analytical treatment for a two-layer multiplex, which results in the introduction of an extra inertial term accounting for structural differences. Numerical validation of the predictions highlights the usefulness of our approach, especially for small or moderate topological differences in the intra-layer coupling. Moreover, we identify a non-trivial relationship connecting the betweenness centrality of the missing links and the intra-layer coupling strength. Finally, by the use of multiplexed layers of electronic circuits, we study the inter-layer synchronization as a function of the removed links.

  18. Process Conditions of Forming the Surface Layer of Aluminum Powder Product by Layer-by-layer Laser Sintering

    Science.gov (United States)

    Saprykina, N. A.; Saprykin, A. A.; Ibragimov, E. A.; Arkhipova, D. A.

    2016-07-01

    The paper presents data on state of the art in selective laser sintering of products. Layer-by-layer sintering is shown to be a future-oriented technology, making it possible to synthesize products of metal powder materials. Factors, influencing the quality of a sintered product, are revealed in the paper. It presents outcomes of experiments, focused on the dependence of surface layer thickness of sintered aluminum powder PA-4 on laser processing conditions. Basic factors, influencing the quality of a sintered surface layer include laser power, speeds of scanning and moving the laser beam on the layer of powder. Thickness of the sintered layer varies from 0.74 to 1.55 mm, as the result of changing the laser processing conditions.

  19. The smear layer in endodontics - a review.

    Science.gov (United States)

    Violich, D R; Chandler, N P

    2010-01-01

    Root canal instrumentation produces a layer of organic and inorganic material called the smear layer that may also contain bacteria and their by-products. It can prevent the penetration of intracanal medicaments into dentinal tubules and influence the adaptation of filling materials to canal walls. This article provides an overview of the smear layer, focusing on its relevance to endodontics. The PubMed database was used initially; the reference list for smear layer featured 1277 articles, and for both smear layer dentine and smear layer root canal revealed 1455 publications. Smear layer endodontics disclosed 408 papers. A forward search was undertaken on selected articles and using some author names. Potentially relevant material was also sought in contemporary endodontic texts, whilst older books revealed historic information and primary research not found electronically, such that this paper does not represent a 'classical' review. Data obtained suggests that smear layer removal should enhance canal disinfection. Current methods of smear removal include chemical, ultrasonic and laser techniques - none of which are totally effective throughout the length of all canals or are universally accepted. If smear is to be removed, the method of choice seems to be the alternate use of ethylenediaminetetraacetic acid and sodium hypochlorite solutions. Conflict remains regarding the removal of the smear layer before filling root canals, with investigations required to determine the role of the smear layer in the outcomes of root canal treatment.

  20. Nanomanufacturing : nano-structured materials made layer-by-layer.

    Energy Technology Data Exchange (ETDEWEB)

    Cox, James V.; Cheng, Shengfeng; Grest, Gary Stephen; Tjiptowidjojo, Kristianto (University of New Mexico); Reedy, Earl David, Jr.; Fan, Hongyou; Schunk, Peter Randall; Chandross, Michael Evan; Roberts, Scott A.

    2011-10-01

    Large-scale, high-throughput production of nano-structured materials (i.e. nanomanufacturing) is a strategic area in manufacturing, with markets projected to exceed $1T by 2015. Nanomanufacturing is still in its infancy; process/product developments are costly and only touch on potential opportunities enabled by growing nanoscience discoveries. The greatest promise for high-volume manufacturing lies in age-old coating and imprinting operations. For materials with tailored nm-scale structure, imprinting/embossing must be achieved at high speeds (roll-to-roll) and/or over large areas (batch operation) with feature sizes less than 100 nm. Dispersion coatings with nanoparticles can also tailor structure through self- or directed-assembly. Layering films structured with these processes have tremendous potential for efficient manufacturing of microelectronics, photovoltaics and other topical nano-structured devices. This project is designed to perform the requisite R and D to bring Sandia's technology base in computational mechanics to bear on this scale-up problem. Project focus is enforced by addressing a promising imprinting process currently being commercialized.

  1. S-layer nanoglycobiology of bacteria.

    Science.gov (United States)

    Messner, Paul; Steiner, Kerstin; Zarschler, Kristof; Schäffer, Christina

    2008-08-11

    Cell surface layers (S-layers) are common structures of the bacterial cell envelope with a lattice-like appearance that are formed by a self-assembly process. Frequently, the constituting S-layer proteins are modified with covalently linked glycan chains facing the extracellular environment. S-layer glycoproteins from organisms of the Bacillaceae family possess long, O-glycosidically linked glycans that are composed of a great variety of sugar constituents. The observed variations already exceed the display found in eukaryotic glycoproteins. Recent investigations of the S-layer protein glycosylation process at the molecular level, which has lagged behind the structural studies due to the lack of suitable molecular tools, indicated that the S-layer glycoprotein glycan biosynthesis pathway utilizes different modules of the well-known biosynthesis routes of lipopolysaccharide O-antigens. The genetic information for S-layer glycan biosynthesis is usually present in S-layer glycosylation (slg) gene clusters acting in concert with housekeeping genes. To account for the nanometer-scale cell surface display feature of bacterial S-layer glycosylation, we have coined the neologism 'nanoglycobiology'. It includes structural and biochemical aspects of S-layer glycans as well as molecular data on the machinery underlying the glycosylation event. A key aspect for the full potency of S-layer nanoglycobiology is the unique self-assembly feature of the S-layer protein matrix. Being aware that in many cases the glycan structures associated with a protein are the key to protein function, S-layer protein glycosylation will add a new and valuable component to an 'S-layer based molecular construction kit'. In our long-term research strategy, S-layer nanoglycobiology shall converge with other functional glycosylation systems to produce 'functional' S-layer neoglycoproteins for diverse applications in the fields of nanobiotechnology and vaccine technology. Recent advances in the field of

  2. Intermetallic Phase on the Interface of Ag-Au-Pd/Al Structure

    Directory of Open Access Journals (Sweden)

    Hao-Wen Hsueh

    2014-01-01

    Full Text Available Three wires, Au, Cu, and Ag-Au-Pd, were bonded on an Al pad, inducing IMC growth by a 155 hr high temperature storage (HTS so that the electrical resistance was increased and critical fusing current density (CFCD decreased. Observations of the Ag-Au-Pd wire after HTS (0–1000 hr indicated that IMC between the Ag-Au-Pd wire and Al Pad was divided into three layers: Ag2Al layers above and below the bonding interface and a polycrystal thin layer above the total IMC. A high percentage of Pd and Au existed in this 200 nm thin layer, and could suppress Al diffusion into the Ag matrix to inhibit IMC growth. After PCT-1000 hr, a noncontinuous structure still remained between the IMC layer and interface, and the main phase of IMC was (Ag, Au, Pd2Al with a hexagonal structure.

  3. Synthesis of Layered Double Hydroxide Single-Layer Nanosheets in Formamide.

    Science.gov (United States)

    Yu, Jingfang; Liu, Jingjing; Clearfield, Abraham; Sims, Johnathan E; Speiegle, Michael T; Suib, Steven L; Sun, Luyi

    2016-11-21

    Layered double hydroxide (LDH) single-layer nanosheets were synthesized through a single-step process in the presence of formamide. This one-step process is simple, fast, and efficient and thus is potentially viable for large-scale production. Two key factors for the growth of LDH single-layer nanosheets, formamide concentration and LDH layer charge, were investigated thoroughly. A higher formamide concentration and a higher LDH layer charge are favorable for the growth of LDH single-layer nanosheets. The LDH single-layer nanosheets obtained at the premium formamide concentration and LDH layer charge were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), and atomic force micrscopy (AFM). Poly(vinyl alcohol) (PVA)/LDH nanocomposite coatings were also prepared. The coated polyethylene terephthalate (PET) and poly(lactic acid) (PLA) films exhibited significantly improved oxygen gas barrier properties thanks to the well-dispersed and -aligned LDH single-layer nanosheets in the coating.

  4. Synchronization in networks with multiple interaction layers

    CERN Document Server

    del Genio, Charo I; Bonamassa, Ivan; Boccaletti, Stefano

    2016-01-01

    The structure of many real-world systems is best captured by networks consisting of several interaction layers. Understanding how a multi-layered structure of connections affects the synchronization properties of dynamical systems evolving on top of it is a highly relevant endeavour in mathematics and physics, and has potential applications to several societally relevant topics, such as power grids engineering and neural dynamics. We propose a general framework to assess stability of the synchronized state in networks with multiple interaction layers, deriving a necessary condition that generalizes the Master Stability Function approach. We validate our method applying it to a network of R\\"ossler oscillators with a double layer of interactions, and show that highly rich phenomenology emerges. This includes cases where the stability of synchronization can be induced even if both layers would have individually induced unstable synchrony, an effect genuinely due to the true multi-layer structure of the interact...

  5. Effect of Rare-Earth (La, Ce, and Y) Additions on the Microstructure and Mechanical Behavior of Sn-3.9Ag-0.7Cu Solder Alloy

    Science.gov (United States)

    Dudek, M. A.; Chawla, N.

    2010-03-01

    In this article, we report on the microstructure and mechanical properties of Ce- and Y-containing Sn-3.9Ag-0.7Cu solders. The microstructures of both as-processed solder and solder joints containing rare-earth (RE) elements (up to 0.5 wt pct) are more refined compared to conventional Sn-3.9Ag-0.7Cu, with decreases in secondary Sn dendrite size and spacing and a thinner Cu6Sn5 intermetallic layer at the Cu/solder interface. These results agree well with similar observations seen in La-containing solders reported previously. The monotonic shear behavior of reflowed Sn-3.9Ag-0.7Cu- X(Ce, Y)/Cu lap shear joints was studied as well as the creep behavior at 368 K (95 °C). The data were compared with results obtained for Sn-3.9Ag-0.7Cu and Sn-3.9Ag-0.7Cu- XLa alloys. All RE-containing alloys exhibited creep behavior similar to Sn-3.9Ag-0.7Cu. Alloys with Ce additions exhibited a small decrease in ultimate shear strength but higher elongations compared with Sn-Ag-Cu. Similar observations were seen in La-containing solders. The influence of the RE-containing intermetallics (CeSn3 and YSn3) that form in these alloys on the microstructural refinement, solidification behavior, and mechanical performance of these novel materials is discussed.

  6. Hydrogen in magnesium palladium thin layer structures

    OpenAIRE

    Kruijtzer, G. L.

    2008-01-01

    In this thesis, the study of hydrogen storage, absorption and desorption in magnesium layers is described. The magnesium layers have a thickness of 50-500 nm and are covered by a palladium layer which acts as a hydrogen dissociation/association catalyst. The study was preformed under ultra high vacuum conditions to avoid oxygen contamination. The main analysis techniques were RBS, ERD and TDS.

  7. A spiral antenna sandwiched by dielectric layers

    OpenAIRE

    Nakano, Hisamatsu; Ikeda, Masakazu; Hitosugi, Kazuo; Yamauchi, Junji

    2004-01-01

    An infinitesimally thin spiral antenna, sandwiched by bottom and top dielectric layers having the same relative permittivity, is analyzed under the condition that the dielectric layers are of finite extent and the antenna is backed by an infinite conducting plane. As the thickness of the top dielectric layer increases, the input impedance and axial ratio (AR) vary in an oscillatory fashion, with a period slightly larger than one-half of the guided wavelength of a wave propagating in an unboun...

  8. Gap Waves in Piezoelectric layered Medium

    Directory of Open Access Journals (Sweden)

    Danoyan Z.N.

    2007-03-01

    Full Text Available In the present paper the conditions of existence of shear electroelastic gap waves in piezoelectric-vacuum-dielectric layered system are found. It is shown that in the discontact layered system the gap electroelastic waves can be propagated. It is considered the limiting case when the thickness of vacuuming layer tends to zero. It is proved that the statement of the problem is true when there is no acoustic contact between piezoelectric and dielectric grounded media.

  9. Size distributions of boundary-layer clouds

    Energy Technology Data Exchange (ETDEWEB)

    Stull, R.; Berg, L.; Modzelewski, H. [Univ. of Wisconsin, Madison, WI (United States)

    1996-04-01

    Scattered fair-weather clouds are triggered by thermals rising from the surface layer. Not all surface layer air is buoyant enough to rise. Also, each thermal has different humidities and temperatures, resulting in interthermal variability of their lifting condensation levels (LCL). For each air parcel in the surface layer, it`s virtual potential temperature and it`s LCL height can be computed.

  10. Multi-layer seal for electrochemical devices

    Science.gov (United States)

    Chou, Yeong-Shyung [Richland, WA; Meinhardt, Kerry D [Kennewick, WA; Stevenson, Jeffry W [Richland, WA

    2010-09-14

    Multi-layer seals are provided that find advantageous use for reducing leakage of gases between adjacent components of electrochemical devices. Multi-layer seals of the invention include a gasket body defining first and second opposing surfaces and a compliant interlayer positioned adjacent each of the first and second surfaces. Also provided are methods for making and using the multi-layer seals, and electrochemical devices including said seals.

  11. Hall effect in organic layered conductors

    Directory of Open Access Journals (Sweden)

    R.A.Hasan

    2006-01-01

    Full Text Available The Hall effect in organic layered conductors with a multisheeted Fermi surfaces was considered. It is shown that the experimental study of Hall effect and magnetoresistance anisotropy at different orientations of current and a quantizing magnetic field relative to the layers makes it possible to determine the contribution of various charge carriers groups to the conductivity, and to find out the character of Fermi surface anisotropy in the plane of layers.

  12. Superconductive articles including cerium oxide layer

    Science.gov (United States)

    Wu, Xin D.; Muenchausen, Ross E.

    1993-01-01

    A ceramic superconductor comprising a metal oxide substrate, a ceramic high temperature superconductive material, and a intermediate layer of a material having a cubic crystal structure, said layer situated between the substrate and the superconductive material is provided, and a structure for supporting a ceramic superconducting material is provided, said structure comprising a metal oxide substrate, and a layer situated over the surface of the substrate to substantially inhibit interdiffusion between the substrate and a ceramic superconducting material deposited upon said structure.

  13. Cation Permeability in Soybean Aleurone Layer

    OpenAIRE

    Noda, Hiroko; Fukuda, Mitsuru

    1998-01-01

    The permeation of water and ions into bean seeds is essential for processing and cooking of beans. The permeability of cations, K, Na, Ca, and Mg ions, into soybean seed tissue, especially aleurone layer, during water uptake was investigated to characterize the ion permeation into soybeans. Aleurone layers and seed coats contained relatively high concentration of endogenous K and Ca ions, and endogenous Ca ion, respectively. The amounts of Ca ion entered seed coats and aleurone layers were gr...

  14. Multi-layer seal for electrochemical devices

    Science.gov (United States)

    Chou, Yeong-Shyung [Richland, WA; Meinhardt, Kerry D [Kennewick, WA; Stevenson, Jeffry W [Richland, WA

    2010-11-16

    Multi-layer seals are provided that find advantageous use for reducing leakage of gases between adjacent components of electrochemical devices. Multi-layer seals of the invention include a gasket body defining first and second opposing surfaces and a compliant interlayer positioned adjacent each of the first and second surfaces. Also provided are methods for making and using the multi-layer seals, and electrochemical devices including said seals.

  15. Manganese containing layer for magnetic recording media

    Science.gov (United States)

    Lambeth, David N.; Lee, Li-Lien; Laughlin, David E.

    1999-01-01

    The present invention provides for a magnetic recording media incorporating Mn-containing layers between a substrate and a magnetic layer to provide media having increased coercivity and lower noise. The Mn-containing layer can be incorporated in a rotating, translating or stationary recording media to operate in conjunction with magnetic transducing heads for recording and reading of magnetic data, as well as other applications. The magnetic recording medium of the invention preferably includes a Co or Co alloy film magnetic layer, and Mn-containing layer, preferably comprised of VMn, TiMn, MnZn, CrMnMo, CrMnW, CrMnV, and CrMnTi, and most preferably a CrMn alloy, disposed between the substrate and the magnetic layer to promote an epitaxial crystalline structure in the magnetic layer. The medium can further include seed layers, preferably polycrystalline MgO for longitudinal media, underlayers, and intermediate layers. Underlayers and intermediate layers are comprised of materials having either an A2 structure or a B2-ordered crystalline structure disposed between the seed layer and the magnetic layer. Materials having an A2 structure are preferably Cr or Cr alloys, such as CrV, CrMo, CrW and CrTi. Materials having a B2-ordered structure having a lattice constant that is substantially comparable to that of Cr, such as those preferably selected from the group consisting of NiAl, AILCo, FeAl, FeTi, CoFe, CoTi, CoHf, CoZr, NiTi, CuBe, CuZn, A-LMn, AlRe, AgMg, and Al.sub.2 FeMn.sub.2, and is most preferably FeAl or NiAl.

  16. Generalized approach to design multi-layer stacks for enhanced optical detectability of ultrathin layers

    Science.gov (United States)

    Hutzler, A.; Matthus, C. D.; Rommel, M.; Frey, L.

    2017-01-01

    The optical detectability of ultrathin conductive films (down to one atomic layer) can be enhanced by choosing distinct layer-stacks. A simple analytical approach using the transfer matrix method is applied for calculating the reflectance of arbitrary multi-layer stack systems with and without the ultrathin layer of interest on top in a wide wavelength range, including both the visible spectrum and the ultraviolet spectrum. Then, the detectability defined by the Michelson contrast was calculated. Performing these calculations for thickness variations of the individual layers in the stack allows determining optimum layer thicknesses, e.g., maximum overall contrast or maximum contrast for a given wavelength. To demonstrate the validity of the methodology, two thin film stacks were investigated, which use p-type silicon as a substrate material and partially covered by a single-layer graphene as a top layer. For each stack, two samples with different layer thicknesses were fabricated and their experimentally determined reflectance was compared to the calculated values. The first system consists of a single SiO2 layer with a thickness of 147 nm and 304 nm, respectively, and the second is a double layer stack consisting of a Si3N4 layer with a thickness of 54 nm and 195 nm, respectively, on top of an 11 nm SiO2 film. The Michelson contrast of single-layer graphene flakes on the latter layer stacks becomes very high (absolute value of more than 0.3) in the visible wavelength range. Additionally, in the UV-B range a large difference in the reflection of selected SiO2 layer thicknesses on silicon substrates with and without single-layer graphene on top is found with a decrease in the measured reflectance of up to 33%. The measured and calculated values showed a high conformity suggesting this approach usable for the calculation of reflectance and transmittance properties of arbitrary layer stack systems including thin conductive layers.

  17. Investigating the Effects of Lead Forming Parameters on Intermetallic Layer Crack Using the Finite-Element Method

    Science.gov (United States)

    Chin, J. W. C.; Kok, C. K.; Rajmohan, M. M.; Yeo, V. S. H.; Said, M. R.

    2012-04-01

    The lead trim-and-form process is important in the manufacturing of programmable logic devices, microprocessors, and memories. Normally, inspection of a chip package is performed in a lead inspection machine after the lead forming process to detect defects on the leads. One such defect is the lead intermetallic compound (IMC) crack, exhibiting itself as plating crack. In this study, IMC crack of package leads, which causes loose connection between the copper lead and the tin plating, was analyzed using the finite-element method. The simulation results were verified by matching the simulated and actual formed lead profile. Simulation results showed a strong correlation between IMC crack after forming and aging and high residual tensile strain induced during lead forming. A proposal was made to resolve the crack issue by performing design of experiment (DOE) to reduce the residual tensile strain of the lead upon forming. Three optimization parameters were chosen, namely the forming angle, the shank angle, and the pre-forming angle. It is shown that, with the optimized parameter setting, a reduction of the residual strain can be achieved, thus minimizing the risk of IMC crack.

  18. Reverse engineering of multi-layer films

    Directory of Open Access Journals (Sweden)

    Effendi Widjaja

    2011-03-01

    Full Text Available This contribution introduces the combined application of Raman microscopy and band-target entropy minimization (BTEM in order to successfully reverse-engineer a multi-layer packaging material. Three layers are identified, namely, polyethylene, a paper and talc layer (with two distinct cellulose forms, and a poly-styrene co-polymer composite containing anatase and calcite. This rapid and non-destructive approach provides a unique opportunity for the assessment of multi-layer composites, including the constitution of the additives present.

  19. Method of Thermocleaving a Polymer Layer

    DEFF Research Database (Denmark)

    2010-01-01

    A method of thermocleaving a thermocleavable polymer layer which is in thermal contact with a heat sensitive component that is not tolerant of the temperature required for thermocleavage of the thermocleavable polymer layer, in which the thermocleavable polymer layer is illuminated with a light...... source having a wavelength range more strongly absorbed by the thermocleavable polymer and substantially less strongly absorbed by the heat sensitive component, such that the thermocleavable polymer layer reaches a temperature sufficient to cause thermocleavage of the polymer without causing detrimental...

  20. Boundary layer heights derived from velocity spectra

    Energy Technology Data Exchange (ETDEWEB)

    Hoejstrup, J.; Barthelmie, R.J. [Risoe National Lab., Roskilde (Denmark); Kaellstrand, B. [Univ. of Uppsala, Uppsala (Sweden)

    1997-10-01

    It is a well-known fact that the height of the mixed layer determines the size of the largest and most energetic eddies that can be observed in the unstable boundary layer, and consequently a peak can be observed in the power spectra of the along-wind velocity component at scales comparable to the mixed layer depth. We will now show how the mixed layer depth can be derived from the u-specta and the results will be compared with direct measurements using pibal and tethersonde measurements. (au)

  1. Radioluminescent nuclear batteries with different phosphor layers

    Science.gov (United States)

    Hong, Liang; Tang, Xiao-Bin; Xu, Zhi-Heng; Liu, Yun-Peng; Chen, Da

    2014-11-01

    A radioluminescent nuclear battery based on the beta radioluminescence of phosphors is presented, and which consists of 147Pm radioisotope, phosphor layers, and GaAs photovoltaic cell. ZnS:Cu and Y2O2S:Eu phosphor layers for various thickness were fabricated. To investigate the effect of phosphor layer parameters on the battery, the electrical properties were measured. Results indicate that the optimal thickness ranges for the ZnS:Cu and Y2O2S:Eu phosphor layers are 12 mg cm-2 to 14 mg cm-2 and 17 mg cm-2 to 21 mg cm-2, respectively. ZnS:Cu phosphor layer exhibits higher fluorescence efficiency compared with the Y2O2S:Eu phosphor layer. Its spectrum properly matches the spectral response of GaAs photovoltaic cell. As a result, the battery with ZnS:Cu phosphor layer indicates higher energy conversion efficiency than that with Y2O2S:Eu phosphor layer. Additionally, the mechanism of the phosphor layer parameters that influence the output performance of the battery is discussed through the Monte Carlo method and transmissivity test.

  2. Electroactive functional hybrid layered nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Destri, Giovanni Li; Torrisi, Vanna; Marletta, Giovanni [Laboratory for Molecular Surfaces and Nanotechnology (LAMSUN) - University of Catania and CSGI - Catania (Italy)

    2012-07-11

    Two methodologies to build new nanostructured hybrid layered nanocomposites are presented. The first one involves the preparation of hybrid metal/polymer nanolayers (NLs) by combining two monolayer preparation techniques: Horizontal Precipitation Langmuir Blodgett method (HP-ML), for copolymer monolayers and sputter deposition technique, for Au NLs deposition. The second methodology is aimed to prepare regular arrays of nanopores, with diameter ranging between 40-100 nm, in ultra-thin films of electroactive polymers, to obtain embedded regular arrays of nanopores filled by a further electroactive organic component. The produced hybrid MLs have been characterized by means of X-ray Photoelectron Spectroscopy (XPS), Atomic Force Microscopy (AFM) and Grazing Incidence X-ray Diffraction (GI-XRD). In the first case, current-voltage (I-V) measurements demonstrate that the multilayers exhibit a bipolar conduction behaviour (electrons and holes carriers), with a peculiar transition in the nature of the majority carriers (from holes to electrons) above a threshold number of bilayers. In the second case, it is found that the degree of pore filling, as well as the polymer crystallinity can be easily modulated, prompting the tuning of the photoresponse of the nanocomposites.

  3. Virtual Heterogeneous Model Integration Layer

    Directory of Open Access Journals (Sweden)

    Muhammad Ali Memon

    2016-05-01

    Full Text Available The classic way of building a software today sim-plistically consists in connecting a piece of code calling a method with the piece of code implementing that method. We consider these piece of code (software systems not calling anything, behaving in a non deterministic way and providing complex sets of services in different domains. In software engineering reusability is the holly grail, and specially the reusability of code from autonomus tools requires powerful compostion/integration mechanisms. These systems are developed by different developers and being modified inceremently. Integrating these autonomous tools generate various conflicts. To deal with these conflicts, current integration mechanisms defines specific set of rules to resolve these conflicts and accompalish integration. Indeed still there is a big chance that changes made by other developers, or they update their changes in order to make them compliant with other developers cancel the updates done by others. The approach presented here claims three contributions in the field of Hetrogeneous Software Integration. First, this approach eliminate the need of conflicts resolving mechanism. Secondly, it provides the mechanism to work in the presence of conflicts without resolving them. Finally, contribution is that the integration mechanism does not affect if either of the system evolves. We do this by introducing an intermediate virtual layer between two systems that introduce a delta models which consist of three parts; viability that share required elements, hiding that hide conflicting elements and aliasing that aliases same concepts in both systems.

  4. Hollow glass for insulating layers

    Science.gov (United States)

    Merticaru, Andreea R.; Moagar-Poladian, Gabriel

    1999-03-01

    Common porous materials, some of which will be considered in the chapters of this book, include concrete, paper, ceramics, clays, porous semiconductors, chromotography materials, and natural materials like coral, bone, sponges, rocks and shells. Porous materials can also be reactive, such as in charcoal gasification, acid rock dissolution, catalyst deactivation and concrete. This study continues the investigations about the properties of, so-called, hollow glass. In this paper is presented a computer simulation approach in which the thermo-mechanical behavior of a 3D microstructure is directly computed. In this paper a computer modeling approach of porous glass is presented. One way to test the accuracy of the reconstructed microstructures is to computed their physical properties and compare to experimental measurement on equivalent systems. In this view, we imagine a new type of porous type of glass designed as buffer layer in multilayered printed boards in ICs. Our glass is a variable material with a variable pore size and surface area. The porosity could be tailored early from the deposition phases that permitting us to keep in a reasonable balance the dielectric constant and thermal conductivity.

  5. Spray Layer-by-Layer Assembled Clay Composite Thin Films as Selective Layers in Reverse Osmosis Membranes.

    Science.gov (United States)

    Kovacs, Jason R; Liu, Chaoyang; Hammond, Paula T

    2015-06-24

    Spray layer-by-layer assembled thin films containing laponite (LAP) clay exhibit effective salt barrier and water permeability properties when applied as selective layers in reverse osmosis (RO) membranes. Negatively charged LAP platelets were layered with poly(diallyldimethylammonium) (PDAC), poly(allylamine) (PAH), and poly(acrylic acid) (PAA) in bilayer and tetralayer film architectures to generate uniform films on the order of 100 nm thick that bridge a porous poly(ether sulfone) support to form novel RO membranes. Nanostructures were formed of clay layers intercalated in a polymeric matrix that introduced size-exclusion transport mechanisms into the selective layer. Thermal cross-linking of the polymeric matrix was used to increase the mechanical stability of the films and improve salt rejection by constraining swelling during operation. Maximum salt rejection of 89% was observed for the tetralayer film architecture, with an order of magnitude increase in water permeability compared to commercially available TFC-HR membranes. These clay composite thin films could serve as a high-flux alternative to current polymeric RO membranes for wastewater and brackish water treatment as well as potentially for forward osmosis applications. In general, we illustrate that by investigating the composite systems accessed using alternating layer-by-layer assembly in conjunction with complementary covalent cross-linking, it is possible to design thin film membranes with tunable transport properties for water purification applications.

  6. Modeling the summertime Arctic cloudy boundary layer

    Energy Technology Data Exchange (ETDEWEB)

    Curry, J.A.; Pinto, J.O. [Univ. of Colorado, Boulder, CO (United States); McInnes, K.L. [CSIRO Division of Atmospheric Research, Mordialloc (Australia)

    1996-04-01

    Global climate models have particular difficulty in simulating the low-level clouds during the Arctic summer. Model problems are exacerbated in the polar regions by the complicated vertical structure of the Arctic boundary layer. The presence of multiple cloud layers, a humidity inversion above cloud top, and vertical fluxes in the cloud that are decoupled from the surface fluxes, identified in Curry et al. (1988), suggest that models containing sophisticated physical parameterizations would be required to accurately model this region. Accurate modeling of the vertical structure of multiple cloud layers in climate models is important for determination of the surface radiative fluxes. This study focuses on the problem of modeling the layered structure of the Arctic summertime boundary-layer clouds and in particular, the representation of the more complex boundary layer type consisting of a stable foggy surface layer surmounted by a cloud-topped mixed layer. A hierarchical modeling/diagnosis approach is used. A case study from the summertime Arctic Stratus Experiment is examined. A high-resolution, one-dimensional model of turbulence and radiation is tested against the observations and is then used in sensitivity studies to infer the optimal conditions for maintaining two separate layers in the Arctic summertime boundary layer. A three-dimensional mesoscale atmospheric model is then used to simulate the interaction of this cloud deck with the large-scale atmospheric dynamics. An assessment of the improvements needed to the parameterizations of the boundary layer, cloud microphysics, and radiation in the 3-D model is made.

  7. Stable water layers on solid surfaces.

    Science.gov (United States)

    Hong, Ying-Jhan; Tai, Lin-Ai; Chen, Hung-Jen; Chang, Pin; Yang, Chung-Shi; Yew, Tri-Rung

    2016-02-17

    Liquid layers adhered to solid surfaces and that are in equilibrium with the vapor phase are common in printing, coating, and washing processes as well as in alveoli in lungs and in stomata in leaves. For such a liquid layer in equilibrium with the vapor it faces, it has been generally believed that, aside from liquid lumps, only a very thin layer of the liquid, i.e., with a thickness of only a few nanometers, is held onto the surface of the solid, and that this adhesion is due to van der Waals forces. A similar layer of water can remain on the surface of a wall of a microchannel after evaporation of bulk water creates a void in the channel, but the thickness of such a water layer has not yet been well characterized. Herein we showed such a water layer adhered to a microchannel wall to be 100 to 170 nm thick and stable against surface tension. The water layer thickness was measured using electron energy loss spectroscopy (EELS), and the water layer structure was characterized by using a quantitative nanoparticle counting technique. This thickness was found for channel gap heights ranging from 1 to 5 μm. Once formed, the water layers in the microchannel, when sealed, were stable for at least one week without any special care. Our results indicate that the water layer forms naturally and is closely associated only with the surface to which it adheres. Our study of naturally formed, stable water layers may shed light on topics from gas exchange in alveoli in biology to the post-wet-process control in the semiconductor industry. We anticipate our report to be a starting point for more detailed research and understanding of the microfluidics, mechanisms and applications of gas-liquid-solid systems.

  8. Mesoporous layer-by-layer ordered nanohybrids of layered double hydroxide and layered metal oxide: highly active visible light photocatalysts with improved chemical stability.

    Science.gov (United States)

    Gunjakar, Jayavant L; Kim, Tae Woo; Kim, Hyo Na; Kim, In Young; Hwang, Seong-Ju

    2011-09-28

    Mesoporous layer-by-layer ordered nanohybrids highly active for visible light-induced O(2) generation are synthesized by self-assembly between oppositely charged 2D nanosheets of Zn-Cr-layered double hydroxide (Zn-Cr-LDH) and layered titanium oxide. The layer-by-layer ordering of two kinds of 2D nanosheets is evidenced by powder X-ray diffraction and cross-sectional high resolution-transmission electron microscopy. Upon the interstratification process, the original in-plane atomic arrangements and electronic structures of the component nanosheets remain intact. The obtained heterolayered nanohybrids show a strong absorption of visible light and a remarkably depressed photoluminescence signal, indicating an effective electronic coupling between the two component nanosheets. The self-assembly between 2D inorganic nanosheets leads to the formation of highly porous stacking structure, whose porosity is controllable by changing the ratio of layered titanate/Zn-Cr-LDH. The resultant heterolayered nanohybrids are fairly active for visible light-induced O(2) generation with a rate of ∼1.18 mmol h(-1) g(-1), which is higher than the O(2) production rate (∼0.67 mmol h(-1) g(-1)) by the pristine Zn-Cr-LDH material, that is, one of the most effective visible light photocatalysts for O(2) production, under the same experimental condition. This result highlights an excellent functionality of the Zn-Cr-LDH-layered titanate nanohybrids as efficient visible light active photocatalysts. Of prime interest is that the chemical stability of the Zn-Cr-LDH is significantly improved upon the hybridization, a result of the protection of the LDH lattice by highly stable titanate layer. The present findings clearly demonstrate that the layer-by-layer-ordered assembly between inorganic 2D nanosheets is quite effective not only in improving the photocatalytic activity of the component semiconductors but also in synthesizing novel porous LDH-based hybrid materials with improved chemical

  9. 内生无铝复合钎料在不同工艺条件下的制备及性能研究%Preparation and properties study of lead-free in-situ composite solder under different conditions

    Institute of Scientific and Technical Information of China (English)

    韩孟婷; 邰枫; 王晓雅; 马立民; 郭福

    2012-01-01

    通过采用不同工艺的内生法在Sn-3.5Ag共晶钎料基体中引入弥散分布的Cu6Sn5颗粒,制得了内生无铅复合钎料.研究了不同工艺条件对该钎料力学性能及电迁移行为的影响.结果表明,在冷却速度(0.1℃/S)较慢时制备的钎料,其内生Cu6Sn5颗粒细小,分布最均匀,且团聚程度较轻,另外,其钎焊接头力学性能最好;通5A电流384 h后,其正负极金属间化合物层厚度的差异保持在约1.2 μm,说明Cu6Sn5颗粒的引入提高了钎料的抗电迁移性能.%Lead-free in-situ composite solders were prepared by introducing Cu6Sn5 grain reinforcements into the Sn-3.5Ag eutectic solder using in-situ methods with different processes. The effects of preparation condition on the mechanical and electromigration properties of the solder were studied. The results show that, for the solder prepared at a relatively low cooling rate (0.1℃/s), its endogenous Cu6Sn5 grains show small size, the most uniform distribution and less agglomeration, and its joint shows the best mechanical performance; After applying 5 A current for 384 h, the difference in the thickness of intermetallic compound between positive and negative poles of the solder keeps at about 1.2 urn, indicating that introduction of Cu6Sn5 reinforcements enhances the anti-electromigration ability of the solder.

  10. Micro-Layer Tomography System

    Directory of Open Access Journals (Sweden)

    M. Navabpour

    2005-08-01

    Full Text Available Introduction & Background: Tomography or plani-graphy is an x-ray imaging system for preserving a certain plane of a radiography object by diffusing the other planes; however, the desired plane does not obtain an optimum sharpness. Meanwhile, relatively nearer points to the rotating axes fixed point have lesser liner velocity than those lying further from the fixed point. Consequently, unwanted obscuring planes occur gradually, that then render the wanted plane somehow blurred, hence the phenomenon known as "tomographic blurring", which diminishes the clinical value of the image. Thus, computerized imaging is uncertain especially to medical authorities. Besides, there is a possibility of dismissing the lesion in some cases, because of the relatively undesirable deep resolution of the system. The present innovation could be an approach to improve current tomography systems by increasing image resolution, obtaining optimum deep resolution, rapid operation, and cost reduction. Material and Methods: Micro-layer tomography has been designed with the benefit of fast x-ray rotating velocity without tube movement, to make images with deep resolution of millimeter fraction, while there is no need of digital images reconstruction in-struments that allows statistical errors to fall to about zero. Furthermore, high-resolution images could be prepared in all planes, including coronal, sagittal, and transverse ones. Likewise, patient treatment and sys-tem maintenance costs are by far less than those in CT scan and MRI. Results & Conclusion: The system quick operation is highly exceptional; therefore, the tomographic slices could be prepared in about less than 0.02 second. The laboratory samples experienced by this system showed a unique result, suggesting the new device preference.

  11. Layer-by-layer tissue microfabrication supports cell proliferation in vitro and in vivo.

    NARCIS (Netherlands)

    Catros, S.; Guillemont, F.; Nandakumar, A.; Ziane, S.; Moroni, L.; Habibovic, P.; Blitterswijk, van C.A.; Rousseau, B.; Chassande, O.; Amedee, J.; Fricain, J-C.

    2012-01-01

    Layer-by-layer biofabrication represents a novel strategy to create three-dimensional living structures with a controlled internal architecture, using cell micromanipulation technologies. Laser assisted bioprinting (LAB) is an effective printing method for patterning cells, biomolecules, and biomate

  12. PRESSURE DRIVEN CONDUCTING POLYMER MEMBRANES DERIVED FROM LAYER BY LAYER FORMATION AND CHARACTERIZATION: A REVIEW

    Directory of Open Access Journals (Sweden)

    IZZATI IZNI YUSOFF

    2016-08-01

    Full Text Available The layer-by-layer method is a technique used for the fabrication of ultra-thin defect free films which involves alternating sequential adsorption of polycations and polyanions, while conducting polymer is characterized by a conjugated structure of alternating single and double bonds. The use of layer-by-layer in producing a membrane for separation has received considerable interest due to its properties. However, the introduction of conducting polymer as a base membrane is relatively new. Therefore, in this review, we discuss in detail three types of LBL techniques (dip, spin and spray layer-by-layer along with their parameters. We will also summarize current developments on the characterization of modified membrane prepared using the layer-by-layer techniques in terms of morphology, physical and chemical properties, and separation performances.

  13. A parcel formulation for Hamiltonian layer models

    NARCIS (Netherlands)

    Bokhove, O.; Oliver, M.

    2009-01-01

    Starting from the three-dimensional hydrostatic primitive equations, we derive Hamiltonian N-layer models with isentropic tropospheric and isentropic or isothermal stratospheric layers. Our construction employs a new parcel Hamiltonian formulation which describes the fluid as a continuum of Hamilton

  14. Delamination of Compressed Thin Layers at Corners

    DEFF Research Database (Denmark)

    Sørensen, Kim D.; Jensen, Henrik Myhre; Clausen, Johan

    2008-01-01

    An analysis of delamination for a thin elastic layer under compression, attached to a substrate at a corner is carried out. The analysis is performed by combining results from interface fracture mechanics and the theory of thin shells. In contrast with earlier results for delamination on a flat...... layers, Fracture mechanics, Crack closure, Steady state crack propagation....

  15. Internal equilibrium layer growth over forest

    DEFF Research Database (Denmark)

    Dellwik, E.; Jensen, N.O.

    2000-01-01

    the magnitude of the scatter. Different theoretical friction velocity profiles for the Internal Boundary Layer (IBL) are tested against the forest data. The results yield information on the Internal Equilibrium Layer (IEL) growth and an equation for the IEL height fur neutral conditions is derived. For stable...

  16. Low-temperature atomic layer epitaxy of AlN ultrathin films by layer-by-layer, in-situ atomic layer annealing.

    Science.gov (United States)

    Shih, Huan-Yu; Lee, Wei-Hao; Kao, Wei-Chung; Chuang, Yung-Chuan; Lin, Ray-Ming; Lin, Hsin-Chih; Shiojiri, Makoto; Chen, Miin-Jang

    2017-01-03

    Low-temperature epitaxial growth of AlN ultrathin films was realized by atomic layer deposition (ALD) together with the layer-by-layer, in-situ atomic layer annealing (ALA), instead of a high growth temperature which is needed in conventional epitaxial growth techniques. By applying the ALA with the Ar plasma treatment in each ALD cycle, the AlN thin film was converted dramatically from the amorphous phase to a single-crystalline epitaxial layer, at a low deposition temperature of 300 °C. The energy transferred from plasma not only provides the crystallization energy but also enhances the migration of adatoms and the removal of ligands, which significantly improve the crystallinity of the epitaxial layer. The X-ray diffraction reveals that the full width at half-maximum of the AlN (0002) rocking curve is only 144 arcsec in the AlN ultrathin epilayer with a thickness of only a few tens of nm. The high-resolution transmission electron microscopy also indicates the high-quality single-crystal hexagonal phase of the AlN epitaxial layer on the sapphire substrate. The result opens a window for further extension of the ALD applications from amorphous thin films to the high-quality low-temperature atomic layer epitaxy, which can be exploited in a variety of fields and applications in the near future.

  17. Reassembly of S-layer proteins

    Science.gov (United States)

    Pum, Dietmar; Sleytr, Uwe B.

    2014-08-01

    Crystalline bacterial cell surface layers (S-layers) represent the outermost cell envelope component in a broad range of bacteria and archaea. They are monomolecular arrays composed of a single protein or glycoprotein species and represent the simplest biological membranes developed during evolution. They are highly porous protein mesh works with unit cell sizes in the range of 3 to 30 nm, and pore sizes of 2 to 8 nm. S-layers are usually 5 to 20 nm thick (in archaea, up to 70 nm). S-layer proteins are one of the most abundant biopolymers on earth. One of their key features, and the focus of this review, is the intrinsic capability of isolated native and recombinant S-layer proteins to form self-assembled mono- or double layers in suspension, at solid supports, the air-water interface, planar lipid films, liposomes, nanocapsules, and nanoparticles. The reassembly is entropy-driven and a fascinating example of matrix assembly following a multistage, non-classical pathway in which the process of S-layer protein folding is directly linked with assembly into extended clusters. Moreover, basic research on the structure, synthesis, genetics, assembly, and function of S-layer proteins laid the foundation for their application in novel approaches in biotechnology, biomimetics, synthetic biology, and nanotechnology.

  18. Introduction to computational techniques for boundary layers

    Energy Technology Data Exchange (ETDEWEB)

    Blottner, F.G.

    1979-09-01

    Finite-difference procedures to solve boundary layer flows in fluid mechanics are explained. The governing equations and the transformations utilized are described. Basic solution techniques are illustrated with the similar boundary layer equations. Nonsimilar solutions are developed for the incompressible equations. Various example problems are solved, and the numerical results in the Fortran listing of the computer codes are presented.

  19. Modelling stable atmospheric boundary layers over snow

    NARCIS (Netherlands)

    Sterk, H.A.M.

    2015-01-01

    Thesis entitled: Modelling Stable Atmospheric Boundary Layers over Snow H.A.M. Sterk Wageningen, 29th of April, 2015 Summary The emphasis of this thesis is on the understanding and forecasting of the Stable Boundary Layer (SBL) over snow-covered surfaces. SBLs typically form at night and in polar re

  20. Dynamical Aspects of Electrostatic Double Layers

    DEFF Research Database (Denmark)

    Raadu, M.A.; Juul Rasmussen, J.

    1988-01-01

    Electrostatic double layers have been proposed as an acceleration mechanism in solar flares and other astrophysical objects. They have been extensively studied in the laboratory and by means of computer simulations. The theory of steady-state double layers implies several existence criteria...

  1. Magnetohydrodynamic cross-field boundary layer flow

    Directory of Open Access Journals (Sweden)

    D. B. Ingham

    1982-01-01

    Full Text Available The Blasius boundary layer on a flat plate in the presence of a constant ambient magnetic field is examined. A numerical integration of the MHD boundary layer equations from the leading edge is presented showing how the asymptotic solution described by Sears is approached.

  2. Steady water waves with multiple critical layers

    CERN Document Server

    Ehrnström, Mats; Wahlén, Erik

    2010-01-01

    We construct small-amplitude periodic water waves with multiple critical layers. In addition to waves with arbitrarily many critical layers and a single crest in each period, two-dimensional sets of waves with several crests and troughs in each period are found. The setting is that of steady two-dimensional finite-depth gravity water waves with vorticity.

  3. Adhesion between Polydimethylsiloxane Layers by Crosslinking

    DEFF Research Database (Denmark)

    Yu, Liyun; Daugaard, Anders Egede; Skov, Anne Ladegaard

    2013-01-01

    stability, and outstanding dielectric properties. The excellent performances of PDMS elastomers enable the realization of pneumatic, electromagnetic, and thermal actuators. In this work, two-layered PDMS films were adhered together by different mixtures of crosslinkers. The double-layered films were...

  4. Modelling stable atmospheric boundary layers over snow

    NARCIS (Netherlands)

    Sterk, H.A.M.

    2015-01-01

    Thesis entitled: Modelling Stable Atmospheric Boundary Layers over Snow H.A.M. Sterk Wageningen, 29th of April, 2015 Summary The emphasis of this thesis is on the understanding and forecasting of the Stable Boundary Layer (SBL) over snow-covered surfaces. SBLs typically form at night and in polar re

  5. Stationary Double Layers in a Collisionless Magnetoplasma

    DEFF Research Database (Denmark)

    Noriyoshi, Sato; Mieno, Tetsu; Hatakeyama, Rikizo;

    1983-01-01

    Stationary double layers are generated in a magnetoplasma by applying potential differences between two heated plates on which the plasma is produced by surface ionization. By measuring the double-layer formation process, a localized potential drop is found to be formed initially in front of the ...

  6. Multi-layered breathing architectural envelope

    DEFF Research Database (Denmark)

    Lund Larsen, Andreas; Foged, Isak Worre; Jensen, Rasmus Lund

    2014-01-01

    A multi layered breathing envelope is developed as a method of natural ventilation. The two main layers consist of mineral wool and air permeable concrete. The mineral wool works as a dynamic insulation and the permeable concrete as a heat recovery system with a high thermal mass for heat storage...

  7. Modelling stable atmospheric boundary layers over snow

    NARCIS (Netherlands)

    Sterk, H.A.M.

    2015-01-01

    Thesis entitled: Modelling Stable Atmospheric Boundary Layers over Snow H.A.M. Sterk Wageningen, 29th of April, 2015 Summary The emphasis of this thesis is on the understanding and forecasting of the Stable Boundary Layer (SBL) over snow-covered surfaces. SBLs typically form at night and in polar

  8. Multi-Layer E-Textile Circuits

    Science.gov (United States)

    Dunne, Lucy E.; Bibeau, Kaila; Mulligan, Lucie; Frith, Ashton; Simon, Cory

    2012-01-01

    Stitched e-textile circuits facilitate wearable, flexible, comfortable wearable technology. However, while stitched methods of e-textile circuits are common, multi-layer circuit creation remains a challenge. Here, we present methods of stitched multi-layer circuit creation using accessible tools and techniques.

  9. Layered Polymeric Optical Systems Using Continuous Coextrusion

    Science.gov (United States)

    2009-01-01

    band[13]. The possibility of fabricating tunable photonic crystals was explored using thermoplastic polyurethane (TPU, n = 1.55) layered against Pebax... losses within the cavity reflection band. Typical emission spectra are shown in Figure 9. The thickness of the dielectric layer determines the spacing...fabrication of refractive index patterns, including gradients and superlattices. The periodic dielectric nature leads to interference effects

  10. Nonlinear Ekman Layer Theories and Their Applications

    Institute of Scientific and Technical Information of China (English)

    TAN Zhemin; FANG Juan; WU Rongsheng

    2006-01-01

    Based on the classical Ekman theory, a series of intermediate boundary layer models, which retain the nonlinear advective process while discard embellishments, have been proposed with the intention to understand the complex nonlinear features of the atmospheric boundary layer and its interaction with the free atmosphere. In this paper, the recent advances in the intermediate boundary-layer dynamic models are reviewed. Several intermediate models such as the boundary-layer models incorporating geostrophic momentum approximation, Ekman momentum approximation, and the weak nonlinear Ekman-layer model are a major theme.With inspection of the theoretical frameworks, the physical meaning and the limitations of each intermediate model are discussed. It is found that the qualitative descriptions of the nonlinear nature in Ekman layer made by the intermediate models are fairly consistent though the details may be different. As the application of the intermediate models is concerned, the application of the intermediate models to the study of the topographic boundary layer, frontogenesis, low-level frontal structure, and low-level jet are especially summarized in this paper. It is shown that the intermediate boundary-layer models have great potential in illustrating the low-level structures of the weather and climate systems as they are coupled with the free atmospheric models.In addition, the important remaining scientific challenges and a prospectus for future research on the intermediate model are also discussed.

  11. Martian Mixed Layer during Pathfinder Mission

    Science.gov (United States)

    Martinez, G. M.; Valero, F.; Vazquez, L.

    2008-09-01

    In situ measurements of the Martian Planetary Boundary Layer (MPBL) encompass only the sur- face layer. Therefore, in order to fully address the MPBL, it becomes necessary to simulate somehow the behaviour of the martian mixed layer. The small-scale processes that happen in the MPBL cause GCM's ([1], [2]) to describe only partially the turbulent statistics, height, convective scales, etc, of the surface layer and the mixed layer. For this reason, 2D and 3D martian mesoscale models ([4], [5]), and large eddy simulations ([4], [6], [7], [8]) have been designed in the last years. Although they are expected to simulate more accurately the MPBL, they take an extremely expensive compu- tational time. Alternatively, we have derived the main turbu- lent characteristics of the martian mixed layer by using surface layer and mixed layer similarity ([9], [10]). From in situ temperature and wind speed measurements, together with quality-tested simu- lated ground temperature [11], we have character- ized the martian mixed layer during the convective hours of Pathfinder mission Sol 25. Mean mixed layer turbulent statistics like tem- perature variance , horizontal wind speed variance , vertical wind speed variance , viscous dissipation rate , and turbu- lent kinetic energy have been calculated, as well as the mixed layer height zi, and the convective scales of wind w? and temperature θ?. Our values, obtained with negligible time cost, match quite well with some previously obtained results via LES's ([4] and [8]). A comparisson between the above obtained mar- tian values and the typical Earth values are shown in Table 1. Convective velocity scale w doubles its counterpart terrestrial typical value, as it does the mean wind speed variances and . On the other hand, the temperature scale θ? and the mean temperature variance are virtually around one order higher on Mars. The limitations of these results concern the va- lidity of the convective mixed layer similarity. This theory

  12. Visualizing Evaluation Structures using Layered Graph Drawings.

    Science.gov (United States)

    Onoue, Yosuke; Kukimoto, Nobuyuki; Sakamoto, Naohisa; Misue, Kazuo; Koyamada, Koji

    2016-03-18

    We propose a method for visualizing evaluation structures that is based on layered graph drawing techniques. An evaluation structure is a hierarchical structure of human cognition extracted from interviews based on the evaluation grid method. An evaluation structure can be defined as a directed acyclic graph (DAG). The Sugiyama framework is a popular method for constructing DAGs. A new layer assignment method that is a part of the Sugiyama framework is proposed to satisfy the requirements for drawing evaluation structures. We formulate a layer assignment problem by considering the sum of squares of arc lengths to be an integer quadratic programming (IQP) problem. Moreover, we transform the IQP problem into an equivalent integer linear programming (ILP) problem for computational efficiency. Evaluations demonstrate that the layered graph drawing with the proposed layer assignment method is preferred by users and aids in the understanding of evaluation structures.

  13. KONSEP INTEGRATION LAYER DALAM PEMBANGUNAN DATA WAREHOUSE

    Directory of Open Access Journals (Sweden)

    I WAYAN PULANTARA

    2012-11-01

    Full Text Available Information availability in exact time is one of keys for correct decision making. One of thesolutions is by developing a Data Warehouse for supporting decision making. In general DataWarehouse contains Dependent Data Mart (DDM, Integration Layer(IL, and Extract-Transform-Load (ETL. Integration Layer is a database that contains data that already integrated,stored in aid for one or more decision support system. For its data source, integration layerrequire Extract-Transform-Load (ETL as supplier for clean and integrated data. IntegrationLayer volume would be much larger than any on dependent data mart that its support, so thefocus aspect in developing Integration Layer as core part of Data Warehouse is how to handle ahuge amount of data in considerable performance. Beside that, interfacing aspect is alsoimportant, e.g. how Integration Layer interact with ETL Process and supporting dependent data.

  14. Experimental investigation of wave boundary layer

    DEFF Research Database (Denmark)

    Sumer, B. Mutlu

    2003-01-01

    A review is presented of experimental investigation of wave boundary layer. The review is organized in six main sections. The first section describes the wave boundary layer in a real-life environment and its simulation in the laboratory in an oscillating water tunnel and in a water tank...... with an oscillating seabed. A brief account is given of measured quantities, measurement techniques (LDA, PIV, flow visualization) and limitations/constraints in the experimental investigation of the wave boundary layer in the laboratory. The second section concentrates on uniform oscillating boundary layers...... with a smooth bed. The boundary layer process is described over the entire range of the Reynolds number (Re from practically nil to Re = O(107)), from the laminar regime to the transitional regime and to the fully developed turbulent regime. The third section focuses on the effect of the boundary roughness...

  15. Traveling Lamb wave in elastic metamaterial layer

    Science.gov (United States)

    Shu, Haisheng; Xu, Lihuan; Shi, Xiaona; Zhao, Lei; Zhu, Jie

    2016-10-01

    The propagation of traveling Lamb wave in single layer of elastic metamaterial is investigated in this paper. We first categorized the traveling Lamb wave modes inside an elastic metamaterial layer according to different combinations (positive or negative) of effective medium parameters. Then the impacts of the frequency dependence of effective parameters on dispersion characteristics of traveling Lamb wave were studied. Distinct differences could be observed when comparing the traveling Lamb wave along an elastic metamaterial layer with one inside the traditional elastic layer. We further examined in detail the traveling Lamb wave mode supported in elastic metamaterial layer, when the effective P and S wave velocities were simultaneously imaginary. It was found that the effective modulus ratio is the key factor for the existence of special traveling wave mode, and the main results were verified by FEM simulations from two levels: the level of effective medium and the level of microstructure unit cell.

  16. Structure of relaminarizing turbulent boundary layers

    Science.gov (United States)

    Ramesh, O.; Patwardhan, Saurabh

    2014-11-01

    Relaminarization of a turbulent boundary layer in a strongly accelerated flow has received a great attention in recent times. It has been found that such relaminarization is a general and regularly occurring phenomenon in the leading-edge region of a swept wing of an airplane (van Dam et al., 1993). In this work, we investigate the effect of initial Reynolds number on the process of relaminarization in turbulent boundary layers. The experimental and numerical investigation of relaminarizing turbulent boundary layers undergoing same history reveals that the boundary layer with higher initial Reynolds number relaminarizes at a lower pressure gradient value compared to the one with lower Reynolds number. This effect can be explained on the inviscid theory proposed earlier in the literature. Further, various parameter criteria proposed to predict relaminarization, are assessed and the structure of relaminarizing boundary layers is investigated. A mechanism for stabilization of near-wall low speed streaks is proposed.

  17. Leidenfrost Vapor Layer Stabilization on Superhydrophobic Surfaces

    Science.gov (United States)

    Vakarelski, Ivan; Patankar, Neelesh; Marston, Jeremy; Chan, Derek; Thoroddsen, Sigurdur

    2012-11-01

    We have performed experiments to investigate the influence of the wettability of a superheated metallic sphere on the stability of a thin vapor layer during the cooling of a sphere immersed in water. For high enough sphere temperatures, a continuous vapor layer (Leidenfrost regime) is observed on the surface of non-superhydrophobic spheres, but below a critical sphere temperature the layer becomes unstable and explosively switches to nuclear boiling regime. In contrast, when the sphere surface is textured and superhydrophobic, the vapor layer is stable and gradually relaxes to the sphere surface until the complete cooling of the sphere, thus avoiding the nuclear boiling transition altogether. This finding could help in the development of heat exchange devices and of vapor layer based drag reducing technologies.

  18. Subsurface Raman analysis of thin painted layers.

    Science.gov (United States)

    Conti, Claudia; Colombo, Chiara; Realini, Marco; Zerbi, Giuseppe; Matousek, Pavel

    2014-01-01

    Here we present, for the first time, an extension of spatially offset Raman spectroscopy to thin (tens of micrometers thick), highly turbid stratified media such as those encountered in paintings. The method permits the non-destructive interrogation of painted layers in situations where conventional Raman microscopy is not applicable due to high turbidity of the top layer(s). The concept is demonstrated by recovering the pure Raman spectra of paint sub-layers that are completely obscured by paint over-layers. Potential application areas include the analysis of paintings in art preservation and restoration avoiding the cross-sectional analysis used currently with this type of samples. The technique also holds promise for the development as a non-destructive subsurface tool for in situ analysis using portable instruments.

  19. Method of forming a nanocluster-comprising dielectric layer and device comprising such a layer

    NARCIS (Netherlands)

    Kochupurackal, J.B.P.; Besling, W.F.A.; Klootwijk, J.H.; Wolters, A.M.; Roozeboom, F.

    2012-01-01

    A method of forming a dielectric layer on a further layer of a semiconductor device is disclosed. The method comprises depositing a dielectric precursor compound and a further precursor compound over the further layer, the dielectric precursor compound comprising a metal ion from the group consistin

  20. Thermoelectric material including conformal oxide layers and method of making the same using atomic layer deposition

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jung Young; Ahn, Dongjoon; Salvador, James R.; Meisner, Gregory P.

    2016-06-07

    A thermoelectric material includes a substrate particle and a plurality of conformal oxide layers formed on the substrate particle. The plurality of conformal oxide layers has a total oxide layer thickness ranging from about 2 nm to about 20 nm. The thermoelectric material excludes oxide nanoparticles. A method of making the thermoelectric material is also disclosed herein.

  1. The influence of varying layer thicknesses on the color predictability of two different composite layering concepts

    NARCIS (Netherlands)

    G. Khashayar; A. Dozic; C.J. Kleverlaan; A.J. Feilzer

    2014-01-01

    Objective Optical properties of teeth are mimicked by composite layering techniques by combining a relatively opaque layer (dentin) with more translucent layers (enamel). However, the replacing material cannot always optically imitate the tooth when applied in the same thickness as that of the natur

  2. The Ocean Boundary Layer beneath Hurricane Frances

    Science.gov (United States)

    Dasaro, E. A.; Sanford, T. B.; Terrill, E.; Price, J.

    2006-12-01

    The upper ocean beneath the peak winds of Hurricane Frances (57 m/s) was measured using several varieties of air-deployed floats as part of CBLAST. A multilayer structure was observed as the boundary layer deepened from 20m to 120m in about 12 hours. Bubbles generated by breaking waves create a 10m thick surface layer with a density anomaly, due to the bubbles, of about 1 kg/m3. This acts to lubricate the near surface layer. A turbulent boundary layer extends beneath this to about 40 m depth. This is characterized by large turbulent eddies spanning the boundary layer. A stratified boundary layer grows beneath this reaching 120m depth. This is characterized by a gradient Richardson number of 1/4, which is maintained by strong inertial currents generated by the hurricane, and smaller turbulent eddies driven by the shear instead of the wind and waves. There is little evidence of mixing beneath this layer. Heat budgets reveal the boundary layer to be nearly one dimensional through much of the deepening, with horizontal and vertical heat advection becoming important only after the storm had passed. Turbulent kinetic energy measurements support the idea of reduced surface drag at high wind speeds. The PWP model correctly predicts the degree of mixed layer deepening if the surface drag is reduced at high wind speed. Overall, the greatest uncertainty in understanding the ocean boundary layer at these extreme wind speeds is a characterization of the near- surface processes which govern the air-sea fluxes and surface wave properties.

  3. Oxygen inhibition layer of composite resins: effects of layer thickness and surface layer treatment on the interlayer bond strength.

    Science.gov (United States)

    Bijelic-Donova, Jasmina; Garoushi, Sufyan; Lassila, Lippo V J; Vallittu, Pekka K

    2015-02-01

    An oxygen inhibition layer develops on surfaces exposed to air during polymerization of particulate filling composite. This study assessed the thickness of the oxygen inhibition layer of short-fiber-reinforced composite in comparison with conventional particulate filling composites. The effect of an oxygen inhibition layer on the shear bond strength of incrementally placed particulate filling composite layers was also evaluated. Four different restorative composites were selected: everX Posterior (a short-fiber-reinforced composite), Z250, SupremeXT, and Silorane. All composites were evaluated regarding the thickness of the oxygen inhibition layer and for shear bond strength. An equal amount of each composite was polymerized in air between two glass plates and the thickness of the oxygen inhibition layer was measured using a stereomicroscope. Cylindrical-shaped specimens were prepared for measurement of shear bond strength by placing incrementally two layers of the same composite material. Before applying the second composite layer, the first increment's bonding site was treated as follows: grinding with 1,000-grit silicon-carbide (SiC) abrasive paper, or treatment with ethanol or with water-spray. The inhibition depth was lowest (11.6 μm) for water-sprayed Silorane and greatest (22.9 μm) for the water-sprayed short-fiber-reinforced composite. The shear bond strength ranged from 5.8 MPa (ground Silorane) to 36.4 MPa (water-sprayed SupremeXT). The presence of an oxygen inhibition layer enhanced the interlayer shear bond strength of all investigated materials, but its absence resulted in cohesive and mixed failures only with the short-fiber-reinforced composite. Thus, more durable adhesion with short-fiber-reinforced composite is expected.

  4. Uncertainties in Surface Layer Modeling

    Science.gov (United States)

    Pendergrass, W.

    2015-12-01

    A central problem for micrometeorologists has been the relationship of air-surface exchange rates of momentum and heat to quantities that can be predicted with confidence. The flux-gradient profile developed through Monin-Obukhov Similarity Theory (MOST) provides an integration of the dimensionless wind shear expression where is an empirically derived expression for stable and unstable atmospheric conditions. Empirically derived expressions are far from universally accepted (Garratt, 1992, Table A5). Regardless of what form of these relationships might be used, their significance over any short period of time is questionable since all of these relationships between fluxes and gradients apply to averages that might rarely occur. It is well accepted that the assumption of stationarity and homogeneity do not reflect the true chaotic nature of the processes that control the variables considered in these relationships, with the net consequence that the levels of predictability theoretically attainable might never be realized in practice. This matter is of direct relevance to modern prognostic models which construct forecasts by assuming the universal applicability of relationships among averages for the lower atmosphere, which rarely maintains an average state. Under a Cooperative research and Development Agreement between NOAA and Duke Energy Generation, NOAA/ATDD conducted atmospheric boundary layer (ABL) research using Duke renewable energy sites as research testbeds. One aspect of this research has been the evaluation of legacy flux-gradient formulations (the ϕ functions, see Monin and Obukhov, 1954) for the exchange of heat and momentum. At the Duke Energy Ocotillo site, NOAA/ATDD installed sonic anemometers reporting wind and temperature fluctuations at 10Hz at eight elevations. From these observations, ϕM and ϕH were derived from a two-year database of mean and turbulent wind and temperature observations. From this extensive measurement database, using a

  5. Nanostructured ZnO Arrays with Self-ZnO Layer Created Using Simple Electrostatic Layer-by-Layer Assembly

    Directory of Open Access Journals (Sweden)

    PilHo Huh

    2012-01-01

    Full Text Available Formation of unique ZnO nanoarrays utilizing photodynamic polymer, surface-relief grating structures, and unique electrostatic layer-by-layer assembly as a simple and economical methodology was demonstrated. Atomic force microscope (AFM, scanning electron microscopy (SEM, and energy-dispersive X-ray (EDAX analysis were employed to characterize elemental composition and morphology of the resulting ZnO nanostructures with self-ZnO layer. Optical behavior of the final product was studied by UV-vis-NIR absorption and photoluminescence (PL spectra.

  6. Study on the Relation between Individual Layer and Multi-layered Nonwoven Geotextile Permeability

    Institute of Scientific and Technical Information of China (English)

    刘丽芳; 储才元

    2003-01-01

    Water permeability is an important property of nonwoven geotextiles used in drainage field, and usually it is obtained by testing individual layer or multi-layered nonwoven geotextiles. However, the permeability coefficient tested by using different layers would be different for the same nonwoven geotextile. In this paper, the relation between them is studied based on Darcy's law. The study shows that vertical permeability coefficients are theoretically invariable no matter how many layers are tested; but experimental results show that vertical permeability coefficients decrease with the increase of nonwoven geotextile layers number.

  7. Simulation of the layer-by-layer synthesis of articles with an electron beam

    Science.gov (United States)

    Rudskoi, A. I.; Kondrat'ev, S. Yu.; Sokolov, Yu. A.; Kopaev, V. N.

    2015-11-01

    The production of powder articles by layer-by-layer electron-beam synthesis is simulated. The following types of spatial distribution of the specific beam power over the surface of a powder layer are analyzed: truncated Gaussian distribution and β distribution. The mathematical description of the layer-by-layer electron- beam synthesis of articles includes a model for the interaction of a scanning electron beam with an article and a model for the heat-and-mass transfer processes that occur during the formation of an article.

  8. Layer-by-Layer Assembly Onto Gold Nanoparticles of Various Size

    Science.gov (United States)

    Kilroy, Andrew; Kessler, Sarah; Dobbins, Tabbetha

    This research focuses on the potential applications of coated gold nanoparticles in medicine. By coating gold nanoparticles in layers of polyelectrolytes, with a final layer of antibodies which targets chemicals uniquely exhibited by cancer cells, we eventually hope to selectively attach the nanoparticles to the cancer cells. The coated nanoparticles are assembled through layer-by-layer coulombic attraction due to the passive zeta potential of the particle and the charged nature of the polyelectrolytes. This poster will explore the potential usefulness of variously sized nanoparticles with various thickness of polyelectrolyte layers.

  9. TEM Investigations on Layered Ternary Ceramics

    Institute of Scientific and Technical Information of China (English)

    Zhijun LIN; Meishuan LI; Yanchun ZHOU

    2007-01-01

    Layered ternary ceramics represent a new class of solids that combine the merits of both metals and ceramics.These unique properties are strongly related to their layered crystal structures and microstructures. The combination of atomic-resolution Z-contrast scanning transmission electron microscopy (STEM) and transmission electron microscopy (TEM), selected area electron diffraction (SAED), convergent beam electron diffraction (CBED) represents a powerful method to link microstructures of materials to macroscopic properties, allowing layered ternary ceramics to be investigated in an unprecedented detail. Vicrostructural information obtained using TEM is useful in understanding the formation mechanism, layered stacking characteristics, and defect structures for layered ternary ceramics down to atomic-scale level; and thus provides insight into understanding the "Processing-Structure-Property" relationship of layered ternary ceramics. Transmission electron microscopic characterizations of layered ternary ceramics in Ti-Si-C, Ti-Al-C, Cr-Al-C, Zr-Al-C, Ta-Al-C and Ti-Al-N systems are reviewed.

  10. Model castings with composite surface layer - application

    Directory of Open Access Journals (Sweden)

    J. Szajnar

    2008-10-01

    Full Text Available The paper presents a method of usable properties of surface layers improvement of cast carbon steel 200–450, by put directly in foundingprocess a composite surface layer on the basis of Fe-Cr-C alloy. Technology of composite surface layer guarantee mainly increase inhardness and aberasive wear resistance of cast steel castings on machine elements. This technology can be competition for generallyapplied welding technology (surfacing by welding and thermal spraying. In range of studies was made cast steel test castings withcomposite surface layer, which usability for industrial applications was estimated by criterion of hardness and aberasive wear resistance of type metal-mineral and quality of joint cast steel – (Fe-Cr-C. Based on conducted studies a thesis, that composite surface layer arise from liquid state, was formulated. Moreover, possible is control of composite layer thickness and its hardness by suitable selection of parameters i.e. thickness of insert, pouring temperature and solidification modulus of casting. Possibility of technology application of composite surface layer in manufacture of cast steel slide bush for combined cutter loader is presented.

  11. Instrument platforms for thin-layer chromatography.

    Science.gov (United States)

    Bernard-Savary, Pierre; Poole, Colin F

    2015-11-20

    High performance column and thin-layer chromatography are both instrumental techniques but differ in that column chromatography requires a fully integrated instrument platform with high pressure capability while for thin-layer chromatography separate devices are used for each unit operation, usually at or close to atmospheric pressure, and afford higher flexibility supporting on-line or off-line operation. The unit operations of thin-layer chromatography are defined as sample application, development and evaluation with derivatization as an optional step. The diversity of equipment for each operation contributes to the flexibility of analysis by thin-layer chromatography and supports manual, semi-automated or full-automation of the separation process. Instrument platforms are more than a convenience as they affect performance, repeatability, sample detectability, and time management. The current trend in thin-layer chromatography is to make the unit operations independent of the user so that analysts can perform other tasks while each step is performed. In addition, in thin-layer chromatography it is general practice to separate several samples simultaneously, and instrument platforms are required to accommodate this feature. In this article, we review contemporary instrumentation employed in thin-layer chromatography for sample application, development, derivatization, photodocumentation, densitometric evaluation, and hyphenation with spectroscopic detectors with an emphasis on the variety and performance of commercially available systems. Some suggestions for best practices and avoidance of common mistakes are included. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Electric fields and double layers in plasmas

    Science.gov (United States)

    Singh, Nagendra; Thiemann, H.; Schunk, R. W.

    1987-05-01

    Various mechanisms for driving double layers in plasmas are briefly described, including applied potential drops, currents, contact potentials, and plasma expansions. Some dynamical features of the double layers are discussed. These features, as seen in simulations, laboratory experiments, and theory, indicate that double layers and the currents through them undergo slow oscillations which are determined by the ion transit time across an effective length of the system in which double layers form. It is shown that a localized potential dip forms at the low potential end of a double layer, which interrupts the electron current through it according to the Langmuir criterion, whenever the ion flux into the double is disrupted. The generation of electric fields perpendicular to the ambient magnetic field by contact potentials is also discussed. Two different situations were considered; in one, a low-density hot plasma is sandwiched between high-density cold plasmas, while in the other a high-density current sheet permeates a low-density background plasma. Perpendicular electric fields develop near the contact surfaces. In the case of the current sheet, the creation of parallel electric fields and the formation of double layers are also discussed when the current sheet thickness is varied. Finally, the generation of electric fields and double layers in an expanding plasma is discussed.

  13. Evolution and formation of shear layers in a developing turbulent boundary layer

    Science.gov (United States)

    Lee, Junghoon; Monty, Jason; Hutchins, Nicholas

    2016-11-01

    The evolution and formation mechanism of shear layers in the outer region of a turbulent boundary layer are investigated using time-resolved PIV datasets of a developing turbulent boundary layer from inception at the trip up to Reτ = 3000 . An analysis of a sequence of instantaneous streamwise velocity fluctuation fields reveals that strong streamwise velocity gradients are prevalent along interfaces where low- and high-speed regions interact. To provide an insight on how such regions are associated with the formation of shear layers in the outer regions, we compute conditional averages of streamwise velocity fluctuations based on a strong shear layer. Our results reveal that one possible mechanism for the generation of shear layers in the outer region is due to the mismatch in the convection velocities between low- and high-speed regions. The results also indicate that the angle of the inclined shear layer is developing in time. In addition, the conditionally averaged velocity fluctuations exhibit a local instability along these shear layers, leading to a shear layer roll-up event as the layers evolve in time. Based on these findings, we propose a conceptual model which describes dynamic interactions of shear layers and their associated large-scale coherent motions. The authors wish to acknowledge the financial support of the Australian Research Council.

  14. Enforced Layer-by-Layer Stacking of Energetic Salts towards High-Performance Insensitive Energetic Materials.

    Science.gov (United States)

    Zhang, Jiaheng; Mitchell, Lauren A; Parrish, Damon A; Shreeve, Jean'ne M

    2015-08-26

    Development of modern high-performance insensitive energetic materials is significant because of the increasing demands for both military and civilian applications. Here we propose a rapid and facile strategy called the "layer hydrogen bonding pairing approach" to organize energetic molecules via layer-by-layer stacking, which grants access to tunable energetic materials with targeted properties. Using this strategy, an unusual energetic salt, hydroxylammonium 4-amino-furazan-3-yl-tetrazol-1-olate, with good detonation performances and excellent sensitivities, was designed, synthesized, and fully characterized. In addition, the expected unique layer-by-layer structure with a high crystal packing coefficient was confirmed by single-crystal X-ray crystallography. Calculations indicate that the layer-stacking structure of this material can absorb the mechanical stimuli-induced kinetic energy by converting it to layer sliding, which results in low sensitivity.

  15. Numerical methods for hypersonic boundary layer stability

    Science.gov (United States)

    Malik, M. R.

    1990-01-01

    Four different schemes for solving compressible boundary layer stability equations are developed and compared, considering both the temporal and spatial stability for a global eigenvalue spectrum and a local eigenvalue search. The discretizations considered encompass: (1) a second-order-staggered finite-difference scheme; (2) a fourth-order accurate, two-point compact scheme; (3) a single-domain Chebychev spectral collocation scheme; and (4) a multidomain spectral collocation scheme. As Mach number increases, the performance of the single-domain collocation scheme deteriorates due to the outward movement of the critical layer; a multidomain spectral method is accordingly designed to furnish superior resolution of the critical layer.

  16. On the theory of asymetrical current layer

    Science.gov (United States)

    Stanev, G.; Konstantinov, I.

    It is noted that a one-dimensional layer has previously been considered with a distribution function constructed by two Maxwellian distributions having a discontinuity in the middle of the layer. The resulting plasma sheet in this case was found to be asymmetric, but the magnetic field did not change sign. A more general self-consistent model is suggested here for current layers in a collisionless plasma which leads to a description of three-dimensional current sheets. A solution of Vlasov's equation is attempted with suitable constants of motion and adiabatic invariants. The current and the charge density are determined, and the Maxwellian equations are given in a closed form.

  17. Atomic layer deposition of nanoporous biomaterials

    Directory of Open Access Journals (Sweden)

    Roger J Narayan

    2010-03-01

    Full Text Available Due to its chemical stability, uniform pore size, and high pore density, nanoporous alumina is being investigated for use in biosensing, drug delivery, hemodialysis, and other medical applications. In recent work, we have examined the use of atomic layer deposition for coating the surfaces of nanoporous alumina membranes. Zinc oxide coatings were deposited on nanoporous alumina membranes using atomic layer deposition. The zinc oxide-coated nanoporous alumina membranes demonstrated antimicrobial activity against Escherichia coli and Staphylococcus aureus bacteria. These results suggest that atomic layer deposition is an attractive technique for modifying the surfaces of nanoporous alumina membranes and other nanostructured biomaterials.

  18. Layered phenomena in the mesopause region

    Science.gov (United States)

    Plane, J. M. C.; Bailey, S. M.; Baumgarten, G.; Rapp, M.

    2015-05-01

    This special issue of the Journal of Atmospheric and Solar-Terrestrial Physics comprises a collection of papers which were mostly presented at the 11th Layered Phenomena in the Mesopause Region (LPMR) Workshop, held at the University of Leeds between 29th July 2013 and 1st August 2013. The topics covered at the workshop included atmospheric dynamics, mesospheric ice clouds, meteoric metal layers, meteoric smoke particles, and airglow layers. There was also a session on the potential of planned sub-orbital spacecraft for making measurements in the mesosphere and lower thermosphere (MLT).

  19. Method for forming a barrier layer

    Energy Technology Data Exchange (ETDEWEB)

    Weihs, Timothy P. (Baltimore, MD); Barbee, Jr., Troy W. (Palo Alto, CA)

    2002-01-01

    Cubic or metastable cubic refractory metal carbides act as barrier layers to isolate, adhere, and passivate copper in semiconductor fabrication. One or more barrier layers of the metal carbide are deposited in conjunction with copper metallizations to form a multilayer characterized by a cubic crystal structure with a strong (100) texture. Suitable barrier layer materials include refractory transition metal carbides such as vanadium carbide (VC), niobium carbide (NbC), tantalum carbide (TaC), chromium carbide (Cr.sub.3 C.sub.2), tungsten carbide (WC), and molybdenum carbide (MoC).

  20. Drag Reduction by Leidenfrost Vapor Layers

    Science.gov (United States)

    Vakarelski, Ivan U.; Marston, Jeremy O.; Chan, Derek Y. C.; Thoroddsen, Sigurdur T.

    2011-05-01

    We demonstrate and quantify a highly effective drag reduction technique that exploits the Leidenfrost effect to create a continuous and robust lubricating vapor layer on the surface of a heated solid sphere moving in a liquid. Using high-speed video, we show that such vapor layers can reduce the hydrodynamic drag by over 85%. These results appear to approach the ultimate limit of drag reduction possible by different methods based on gas-layer lubrication and can stimulate the development of related energy saving technologies.

  1. The Functioning of a Cortex without Layers

    Directory of Open Access Journals (Sweden)

    Julien Guy

    2017-07-01

    Full Text Available A major hallmark of cortical organization is the existence of a variable number of layers, i.e., sheets of neurons stacked on top of each other, in which neurons have certain commonalities. However, even for the neocortex, variable numbers of layers have been described and it is just a convention to distinguish six layers from each other. Whether cortical layers are a structural epiphenomenon caused by developmental dynamics or represent a functionally important modularization of cortical computation is still unknown. Here we present our insights from the reeler mutant mouse, a model for a developmental, “molecular lesion”-induced loss of cortical layering that could serve as ground truth of what an intact layering adds to the cortex in terms of functionality. We could demonstrate that the reeler neocortex shows no inversion of cortical layers but rather a severe disorganization that in the primary somatosensory cortex leads to the complete loss of layers. Nevertheless, the somatosensory system is well organized. When exploring an enriched environment with specific sets of whiskers, activity-dependent gene expression takes place in the corresponding modules. Precise whisker stimuli lead to the functional activation of somatotopically organized barrel columns as visualized by intrinsic signal optical imaging. Similar results were obtained in the reeler visual system. When analyzing pathways that could be responsible for preservation of tactile perception, lemniscal thalamic projections were found to be largely intact, despite the smearing of target neurons across the cortical mantle. However, with optogenetic experiments we found evidence for a mild dispersion of thalamic synapse targeting on layer IV-spiny stellate cells, together with a general weakening in thalamocortical input strength. This weakening of thalamic inputs was compensated by intracortical mechanisms involving increased recurrent excitation and/or reduced feedforward

  2. Drag Reduction by Leidenfrost Vapor Layers

    KAUST Repository

    Vakarelski, Ivan Uriev

    2011-05-23

    We demonstrate and quantify a highly effective drag reduction technique that exploits the Leidenfrost effect to create a continuous and robust lubricating vapor layer on the surface of a heated solid sphere moving in a liquid. Using high-speed video, we show that such vapor layers can reduce the hydrodynamic drag by over 85%. These results appear to approach the ultimate limit of drag reduction possible by different methods based on gas-layer lubrication and can stimulate the development of related energy saving technologies.

  3. Formation of multilayered structures in the layer by layer deposition of colloid particles.

    Science.gov (United States)

    Adamczyk, Zbigniew; Weroński, Paweł; Barbasz, Jakub

    2008-01-01

    Theoretical calculations of particle film formation in the layer by layer (LbL) self-assembling processes have been performed according to the generalized random sequential adsorption (RSA) scheme. The first (precursor) layer was generated using the standard RSA scheme pertinent to homogeneous surface. Formation of the consecutive layers (up to twenty) was simulated for two kinds of particles of equal size. The interaction of two particles of different kind resulted in irreversible and localized adsorption upon contact, whereas particles of the same kind were assumed to interact via the hard potential (no adsorption possible). Using this algorithm particle coverage (2D density) and volume fraction (3D density) were calculated as well as the film thickness as a function of the number of layers. Additionally, the structure of the film was quantitatively characterized in terms of the 2D and 3D pair correlation functions. The simulations revealed that particle concentration distribution in the film was more uniform for low precursor layer density than for higher density, where well-defined layers of closely packed particles appeared. It was also predicted theoretically that the averaged value of particle volume fraction in the uniform film region was rho(LbL)=0.42, which is very close to the maximum packing density equal to 0.382 predicted from the 3D RSA model. On the other hand, the roughness of the film was the lowest at the highest precursor layer density. It was shown that for low precursor layer density the film thickness increased with the number of layers in a nonlinear way. However, for high precursor layer density, the film thickness increased linearly with the number of layers and the average layer thickness was close to the hexagonal layer thickness equal to 1.73a p. It was concluded that our theoretical results can be effectively exploited for interpretation of the LbL processes involving colloid particles and polyelectrolytes.

  4. Numerical modeling of altocumulus cloud layers

    Science.gov (United States)

    Liu, Shuairen

    1998-07-01

    Altocumulus (Ac) clouds are predominantly water clouds and typically less than several hundred meters thick. Ac cloud heights are mid-level, from 2 to 8 km. Ac clouds cover large portions of the Earth and play an important role in the Earth's energy budget through their effects on solar and infrared radiation. A two-dimensional cloud resolving model (CRM) and a one-dimensional turbulent closure model (TCM) are used to study Ac clouds with idealized initial conditions. An elevated mixed layer model (MLM) is developed and the results for the MLM are compared with results for CRM. The impacts of large-scale vertical motion, and solar and IR radiation, the utility of the TCM, the mixed layer characteristics and circulation of Ac layers, the turbulent kinetic energy (TKE) budget, and effects of relative humidify (RH) above the cloud are studied with a series of numerical simulations using the CRM and TCM. The results show that weak large-scale vertical motion may allow for a long lifetime of Ac clouds. In the nocturnal case, feedbacks between the liquid water path (LWP), IR radiation, and entrainment lead to an Ac layer with a nearly steady structure and circulation. The solar radiation in the diurnal case leads to decreases in the LWP, circulation intensity, and entrainment rate during the day. The comparison of TCM and CRM simulations suggests that TCM simulations can portray the basic characteristics of Ac clouds. The Ac convective layer includes mainly the cloud region and a shallow subcloud layer. In the Ac convective layers, the updrafts are wide and weak, whereas the downdrafts are narrow and strong. The updrafts are associated with regions of large cloud water mixing ratio, and the downdrafts with the regions of small cloud water mixing ratio. In Ac layers, the TKE is as large as in stratocumulus-topped-boundary-layer (STBL). The TKE is produced by buoyancy in the cloud region, dissipated by viscous dissipation, and redistributed upward and downward through

  5. Aqueous oxidation reaction enabled layer-by-layer corrosion of semiconductor nanoplates into single-crystalline 2D nanocrystals with single layer accuracy and ionic surface capping.

    Science.gov (United States)

    Ji, Muwei; Xu, Meng; Zhang, Jun; Liu, Jiajia; Zhang, Jiatao

    2016-02-25

    A controllable aqueous oxidation reaction enabled layer-by-layer corrosion has been proposed to prepare high-quality two-dimensional (2D) semiconductor nanocrystals with single layer accuracy and well-retained hexagonal shapes. The appropriate oxidizing agent, such as H2O2, Fe(NO3)3, and HNO3, could not only corrode the layered-crystalline-structured Bi2Te3 nanoplates layer-by-layer to be a single quintuple layer, but also replace the organic barriers to be ionic ligands on the surface synergistically. AFM analysis was used to confirm the layer-by-layer exfoliation from the side to the center. Together with precise XRD, LRTEM and HRTEM characterizations, the controllable oxidation reaction enabled aqueous layer-by-layer corrosion mechanism has been studied.

  6. Weak layer fracture: facets and depth hoar

    Directory of Open Access Journals (Sweden)

    I. Reiweger

    2013-09-01

    Full Text Available Understanding failure initiation within weak snow layers is essential for modeling and predicting dry-snow slab avalanches. We therefore performed laboratory experiments with snow samples containing a weak layer consisting of either faceted crystals or depth hoar. During these experiments the samples were loaded with different loading rates and at various tilt angles until fracture. The strength of the samples decreased with increasing loading rate and increasing tilt angle. Additionally, we took pictures of the side of four samples with a high-speed video camera and calculated the displacement using a particle image velocimetry (PIV algorithm. The fracture process within the weak layer could thus be observed in detail. Catastrophic failure started due to a shear fracture just above the interface between the depth hoar layer and the underlying crust.

  7. Circumpolar Active-Layer Permafrost System (CAPS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Circumpolar Active-Layer Permafrost System (CAPS) contains over 100 data sets pertaining to permafrost and frozen ground topics. It also contains detailed...

  8. Layered models for closed 3-manifolds

    CERN Document Server

    Johnson, Jesse

    2010-01-01

    We define a combinatorial structure on 3-manifolds that combines the model manifolds constructed in Minsky's proof of the ending lamination conjecture with the layered triangulations defined by Jaco and Rubinstein.

  9. Weak layer fracture: facets and depth hoar

    Directory of Open Access Journals (Sweden)

    I. Reiweger

    2013-05-01

    Full Text Available Understanding the fracture behavior of weak snow layers is essential for modeling and predicting dry-snow slab avalanches. We therefore performed laboratory experiments with snow samples containing a weak layer consisting of either faceted crystals or depth hoar. During these experiments the samples were loaded with different loading rates and at various tilt angles until fracture. The strength of the samples decreased with increasing loading rate and increasing tilt angle. Additionally, we took pictures of the side of the samples with a high-speed video camera and calculated the displacement using a particle image velocimetry (PIV algorithm. The fracture process within the weak layer could thus be studied in detail. We found a fracture in shear immediately followed by a collapse of the weak layer.

  10. Double layer dynamics in a collisionless magnetoplasma

    DEFF Research Database (Denmark)

    Iizuka, S.; Michelsen, Poul; Juul Rasmussen, Jens

    1985-01-01

    Investigations of double layer dynamics are performed in a Q-machine plasma by applying a positive step potential to a cold end-plate collector. The double layer created at the grounded plasma source just after the pulse is applied propagates towards the collector with the plasma flow speed. Large...... oscillations occur in the plasma current which is related to a recurring formation and propagation of the double layer. The current is limited during the propagation by a growing negative potential dip formed on the low-potential tail. Similar phenomena appear on the low-potential tail of the stationary double...... layer formed by applying a potential difference between two plasma sources...

  11. Double Layer Dynamics in a Collisionless Magnetoplasma

    DEFF Research Database (Denmark)

    Iizuka, S.; Michelsen, Poul; Juul Rasmussen, Jens

    An experimental investigation of the dynamics of double layers is presented. The experiments are performed in a Q-machine plasma and the double layers are generated by applying a positive step potential to a cold collector plate terminating the plasma column. The double layer is created...... at the grounded plasma source just after the pulse is applied and it propagates towards the collector with a speed around the ion acoustic speed. When the collector is biased positively, large oscillations are obserced in the plasma current. These oscillations are found to be related to a recurring formation...... difference is applied between two plasmas in a Q-machine with two sources. In this case a stationary double layer forms in the plasma column, but the low potential tail is subject to "back and forth" oscillations leading to large amplitude current oscillations....

  12. CropScape - Cropland Data Layer

    Data.gov (United States)

    National Agricultural Statistics Service, Department of Agriculture — The USDA National Agricultural Statistics Service (NASS) releases the annual Cropland Data Layer (CDL) via the NASS CropScape geospatial portal . The CDL product...

  13. Content layer progressive coding of digital maps

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Jensen, Ole Riis

    2000-01-01

    A new lossless context based method is presented for content progressive coding of limited bits/pixel images, such as maps, company logos, etc., common on the WWW. Progressive encoding is achieved by separating the image into content layers based on other predefined information. Information from...... already coded layers are used when coding subsequent layers. This approach is combined with efficient template based context bi-level coding, context collapsing methods for multi-level images and arithmetic coding. Relative pixel patterns are used to collapse contexts. The number of contexts are analyzed....... The new methods outperform existing coding schemes coding digital maps and in addition provide progressive coding. Compared to the state-of-the-art PWC coder, the compressed size is reduced to 60-70% on our layered test images....

  14. Ozone Layer Research and Technical Resources

    Science.gov (United States)

    Access information on research and technical resources related to ozone layer science. This page provides links to research efforts led by organizations such as the National Oceanic and Atmospheric Administration, the United Nations Environment Program, an

  15. Stability of nanocrystalline electrochemically deposited layers

    DEFF Research Database (Denmark)

    Pantleon, Karen; Somers, Marcel A. J.

    2009-01-01

    The technological demand for manufacturing components with complex geometries of micrometer or sub-micrometer dimensions and ambitions for ongoing miniaturization have attracted particular attention to electrochemical deposition methods. Thin layers of electrochemically deposited metals and alloys...

  16. Application Layer Multicast Technology of Streaming Media

    Directory of Open Access Journals (Sweden)

    Jiansheng Liu

    2011-08-01

    Full Text Available With the rapid development of network technology, Internet business has been transferred from a simple text into a host text, audio, video and other streaming services. Application layer multicast is one of the key technologies to protect the large-scale service quality of streaming media system, which has become an important part of study. Based on the application layer multicast technology, it focused on analyzing the effects of application layer multicast to the  large-scale of media streaming system, and summarized the typical characteristics of the system. It takes efficiency of multicast robustness, scalability, and the continuity as evaluation indexes, and summarized the typical multicast. In the end,the drawbacks and develop directions of application layer multicast were discussed.

  17. Surface state and normal layer effects

    Energy Technology Data Exchange (ETDEWEB)

    Klemm, R.A.; Ledvij, M. [Argonne National Lab., IL (United States); Liu, S.H. [Univ. of California, San Diego, CA (United States). Dept. of Physics

    1995-08-01

    In addition to the conducting CuO{sub 2} (S) layers, most high-T{sub c} superconductors also contain other conducting (N) layers, which are only superconducting due to the proximity effect. The combination of S and N layers can give rise to complicated electronic densities of states, leading to quasilinear penetration depth and NMR relaxation rate behavior at low temperatures. Surface states can also complicate the analysis of tunneling and, photoemission measurements. Moreover, geometrical considerations and in homogeneously trapped flux axe possible explanations of the paramagnetic Meissner effect and of corner and ring SQUID experiments. Hence, all of the above experiments could be consistent with isotropic s-wave superconductivity within the S layers.

  18. Mathematical Formulation of Multi-Layer Networks

    CERN Document Server

    De Domenico, Manlio; Cozzo, Emanuele; Kivelä, Mikko; Moreno, Yamir; Porter, Mason A; Gòmez, Sergio; Arenas, Alex

    2013-01-01

    A network representation is useful for describing the structure of a large variety of complex systems. However, most real and engineered systems have multiple subsystems and layers of connectivity, and the data produced by such systems is very rich. Achieving a deep understanding of such systems necessitates generalizing "traditional" network theory, and the newfound deluge of data now makes it possible to test increasingly general frameworks for the study of networks. In particular, although adjacency matrices are useful to describe traditional single-layer networks, such a representation is insufficient for the analysis and description of multiplex and time-dependent networks. One must therefore develop a more general mathematical framework to cope with the challenges posed by multi-layer complex systems. In this paper, we introduce a tensorial framework to study multi-layer networks, and we discuss the generalization of several important network descriptors and dynamical processes ---including degree centr...

  19. An Insolation Activated Dust Layer on Mars

    CERN Document Server

    de Beule, Caroline; Kelling, Thorben; Koester, Marc; Kocifaj, Miroslav

    2015-01-01

    The illuminated dusty surface of Mars acts like a gas pump. It is driven by thermal creep at low pressure within the soil. In the top soil layer this gas flow has to be sustained by a pressure gradient. This is equivalent to a lifting force on the dust grains. The top layer is therefore under tension which reduces the threshold wind speed for saltation. We carried out laboratory experiments to quantify the thickness of this activated layer. We use basalt with an average particle size of 67 $\\mu$m. We find a depth of the active layer of 100 to 200 $\\rm \\mu m$. Scaled to Mars the activation will reduce threshold wind speeds for saltation by about 10%.

  20. THERMAL BOUNDARY LAYER IN CFB BOILER RISER

    Institute of Scientific and Technical Information of China (English)

    Jinwei; Wang; Xinmu; Zhao; Yu; Wang; Xing; Xing; Jiansheng; Zhang; Guangxi; Yue

    2006-01-01

    Measurement of temperature profiles of gas-solid two-phase flow at different heights in commercial-scale circulating fluidized bed (CFB) boilers was carried out. Experimental results showed that the thickness of thermal boundary layer was generally independent of the distance from the air distributor, except when close to the riser outlet. Through analysis of flow and combustion characteristics in the riser, it was found that the main reasons for the phenomena were: 1) the hydrodynamic boundary layer was thinner than the thermal layer and hardly changed along the CFB boiler height, and 2) both radial and axial mass and heat exchanges were strong in the CFB boiler. Numerical simulation of gas flow in the outlet zone confirmed that the distribution of the thermal boundary layer was dominated by the flow field characteristics.