WorldWideScience

Sample records for council regulation ec

  1. EU Customs Protection of Intellectual Property Rights——Council regulation(EC)No.1383/2003 Review%欧盟知识产权海关保护条例——Council egulation(EC)No.1383/2003评析

    Institute of Scientific and Technical Information of China (English)

    张永亮

    2010-01-01

    知识产权海关保护是随着国际贸易出现大量盗版和假冒商品等非法货物贸易的情况下产生并发展起来的一种行之有效的知识产权保护制度.欧盟知识产权海关保护条例的实施有效地遏制了盗版和假冒商品对国际贸易秩序的危害,对欧盟知识产权权利人利益的维护起到了至关重要的作用.但其不足也很明显:Council Regulation(EC)No.1383/2003的执行很大程度上是依赖于各成员国政府和海关当局,另外Council Regulation(EC)No.1383/2003允许成员国时其相关内容做出细化或作出不同的规定,这将导致各国海关对知识产权保护出现不同的执法效果.

  2. Council Regulation (EC No. 1099/2009: state of the art and its application in a local health unit in Piedmont, Italy

    Directory of Open Access Journals (Sweden)

    Ginevra Paolucci

    2015-06-01

    Full Text Available In the last decade, the European Union has reinforced the concept of animal welfare throughout the food chain, from breeding to slaughtering. Studies and assessments of economic nature led to the adoption of Regulation EC 1099/2009 and at the end of 2014 this regulation will be applied to all the members involved in the food chain. For this reason several local health units organized different initiatives. The local health unit of Turin no. 4 (ASLTO4 has developed a project aimed to train food business operators (FBO to fulfill all the criteria developed in this Regulation. This initiative was divided into four steps: i communication to the companies about the criteria of the new regulation; ii a training course for official veterinarians; iii slaughterhouse audits in order to get information about animal welfare; iv and a training course for the personnel involved in slaughterhouses. The purpose of this paper was to report the results of the audits in order to identify critical points of structural, instrumental and documentary facilities. Then, the results can be compared with similar studies in order to develop common strategies and intervention areas.

  3. DECISIONS OF ROMANIAN LAW COURTS IN CASES CONCERNING THE INTERPRETATION OF ARTICLE 3 (D OF REGULATION (EC NO 469/2009 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL OF 6 MAY 2009, CONCERNING THE SUPPLEMENTARY PROTECTION CERTIFICATE FOR MEDICINAL PRODUCTS

    Directory of Open Access Journals (Sweden)

    BUCURA IONESCU

    2012-05-01

    Full Text Available The supplementary protection certificate is currently considered to represent an accessory of a national or European patent granted in order to extend the duration of the rights that said patent confers on its owner in respect of an active substance or a combination of active substances. Based on the above-mentioned patent and on the certificate, the owner shall have the exclusive right of manufacturing and commercializing the patented product, as well as the right to oppose to any form of counterfeiting of the patented product. The grant of this protection title for medicaments is regulated on the territory of the European Union by the Regulation (EC No 469/2009 of the European Parliament and of the Council of 6 May 2009 concerning the supplementary protection certificate for medicinal products (Codified version. The conditions for obtaining the certificate are stipulated under Art. 3. The paper is intended to present the decisions made by the Romanian courts in the cases concerning the controversial interpretation of Art. 3 letter d of the Regulation, which provides that the valid authorization to place the medicament on the market in accordance with Directive 2001/83/EC or Directive 2001/82/EC, as the case may be, should be the first authorization to place the product on the market as a medicament. At the same time, the paper presents the differences in the approach and the judgment of such cases by OSIM (State Office for Inventions and Trademarks and by the national courts. The paper aims at analyzing said decisions as compared to the European practice, with a view to identifying solutions for a uniform interpretation of Community legislation at the level of the Romanian courts.

  4. Radiation Protection Of Outside Workers: Implementation Of The EC Council Directive 90/641/EURATOM

    Energy Technology Data Exchange (ETDEWEB)

    Jannsens, A.; Schnuer, K.; Naegele, J. [European Commission, DG Energy and Transport B. EUROFORUM, 4455, L-2920 (Luxembourg); Lefaure, C.; Vaillant, L. [Nuclear Protection Evaluation Centre (CEPN) Batiment Expansion 10000, 28 rue de la Redoute, 92263 Fontenay-aux- Roses (France)

    2006-07-01

    States national regulations. In addition, a Seminar was held in Luxembourg on 29 and 30 November 2005, gathering representatives from EC departments, national regulatory bodies, operators, outside undertakings and from trade unions. The participants discussed measures aimed at coping with these above-mentioned challenges for the radiological protection of outside workers. The paper will provide information on the results of the survey and will present the summaries and conclusions of the discussions of the Luxembourg workshop. (authors)

  5. Impact of EU Council Directive 99/74/EC 'welfare of laying hens' on the competitiveness of the EU egg industry.

    NARCIS (Netherlands)

    Horne, van P.L.M.; Bondt, N.

    2003-01-01

    Because of animal welfare concerns in the EU, from 2012 only enriched cages will be allowed for the housing of laying hens (Council Directive 1999/74/EC). Production in enriched cages will increase the production cost of eggs. At the same time the World Trade Organisation (WTO) has launched a new ro

  6. Developmental regulation of ecdysone receptor (EcR and EcR-controlled gene expression during pharate-adult development of honeybees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Tathyana Rachel Palo Mello

    2014-12-01

    Full Text Available Major developmental transitions in multicellular organisms are driven by steroid hormones. In insects, these, together with juvenile hormone (JH, control development, metamorphosis, reproduction and aging, and are also suggested to play an important role in caste differentiation of social insects. Here, we aimed to determine how EcR transcription and ecdysteroid titers are related during honeybee postembryonic development and what may actually be the role of EcR in caste development of this social insect. In addition, we expected that knocking-down EcR gene expression would give us information on the participation of the respective protein in regulating downstream targets of EcR. We found that in Apis mellifera females, EcR-A is the predominantly expressed variant in postembryonic development, while EcR-B transcript levels are higher in embryos, indicating an early developmental switch in EcR function. During larval and pupal stages, EcR-B expression levels are very low, while EcR-A transcripts are more variable and abundant in workers compared to queens. Strikingly, these transcript levels are opposite to the ecdysteroid titer profile. 20-hydroxyecdysone (20E application experiments revealed that low 20E levels induce EcR expression during development, whereas high ecdysteroid titers seem to be repressive. By means of RNAi-mediated knockdown (KD of both EcR transcript variants we detected the differential expression of 234 poly-A+ transcripts encoding genes such as CYPs, MRJPs and certain hormone response genes (Kr-h1 and ftz-f1. EcR-KD also promoted the differential expression of 70 miRNAs, including highly conserved ones (e.g. miR-133 and miR-375, as well honeybee-specific ones (e.g. miR-3745 and miR-3761. Our results put in evidence a broad spectrum of EcR-controlled gene expression during postembryonic development of honeybees, revealing new facets of EcR biology in this social insect.

  7. Comparing Czech and Slovak Council Newspapers’ Policy and Regulation Development

    Directory of Open Access Journals (Sweden)

    Lenka Waschkova Cisarova

    2015-12-01

    Full Text Available Council newspapers form an integral part of European media systems and, as such, have been analysed for their important contribution to the development of local politics. However, despite a recognition of the media’s important democratic function in the transition countries of Central and Eastern Europe (CEE after the fall of socialism, the consideration of council newspapers’ political role in the Czech Republic and Slovakia have been largely absent in debates surrounding the development of regulatory frameworks until recently. Interestingly, debates regarding local government transparency emerged recently (2011 in the United Kingdom, resulting in the Code of recommended practice on local authority publicity, underscoring the importance of this issue. However, developments in the aforementioned situations demonstrate divergent outcomes in such considerations: the British addressed the causes, the Czechs addressed the symptoms, and the Slovaks have yet to make any headway. This article utilizes qualitative analysis of policy and regulation documents to compare the trajectories of media policy and regulation of council publicity in the Czech Republic and Slovakia, ultimately contrasting it with developments in the UK, suggesting possible future trajectories for the development of this type of regulation in the CEE countries.

  8. Evaluation of EU Risk assessments Existing Chemicals (EC Regulation 793/93)

    NARCIS (Netherlands)

    Bodar CWM; Berthault F; Bruijn JHM de; Leeuwen CJ van; Pronk MEJ; Vermeire TG; CSR

    2002-01-01

    An evaluation was performed on the first group (41) of completed risk assessments for chemicals of the EU priority lists (Existing Chemicals; EC Regulation 793/93). The evaluation focussed on the conclusions of the risk assessments. The EU risk assessment process detected a high number of substance

  9. [Regulation (EC) No. 1394/2007 on advanced therapy medicinal products : Incorporation into national law].

    Science.gov (United States)

    Dwenger, A; Strassburger, J; Schwerdtfeger, W

    2010-01-01

    Regulation (EC) No. 1394/2007 has created a new legal framework for advanced therapy medicinal products (gene therapy medicinal products, somatic cell therapy medicinal products and tissue engineered products). The Regulation is directly applicable in the Member States of the European Union and, in principle, requires no incorporation into national law. However, the amendment of Directive 2001/83/EC, which results from Regulation (EC) No. 1394/2007, has created a need for incorporation into and amendment of the German Medicinal Products Act. This is one of the objectives of the 15th amendment of the German Medicinal Products Act. In particular, the definition "advanced therapy medicinal products" and the special provisions for advanced therapy medicinal products prepared on a non-routine basis, which are based on the special provisions contained in Art. 28 No. 2 of Regulation (EC) No. 1394/2007, are to be incorporated into the German Medicinal Products Act. These special provisions will be explained in detail.

  10. UK air quality modelling for annual reporting 2006 on ambient air quality assessment under Council Directives 96/62/EC, 1999/30/EC and 2000/69/EC

    Energy Technology Data Exchange (ETDEWEB)

    Andrew J. Kent; Susannah Grice; John R. Stedman; Tony J. Bush; Keith J. Vincent; John Abbott (and others)

    2006-11-15

    Directive 96/62/EC on Ambient Air Quality Assessment and Management establishes a framework under which the EU sets limit values or target values for the concentrations of specified air pollutants. Directive 1999/30/EC (the first Daughter Directive) sets the limit values to be achieved for sulphur dioxide, nitrogen dioxide and oxides of nitrogen, particles and lead. Directive 2000/69/EC (the second Daughter Directive) set limits to be achieved for benzene and carbon monoxide. 2005 is the sixth year for which an annual air quality assessment for the first Daughter Directive pollutants is required and the fifth year for which an annual air quality assessment has been undertaken for the second Daughter Directive pollutants. 2006 is the second year for which an annual air quality assessment has been undertaken for the third Daughter Directive. A questionnaire has been completed for submission to the EU containing the results of this air quality assessment. The assessment takes the form of comparisons of measured and modelled air pollutant concentrations with the limit values set out in the Directives. Air quality modelling has been carried out to supplement the information available from the UK national air quality monitoring networks. This report provides a summary of key results from the questionnaire for pollutants included in the first and second Daughter Directives and additional technical information on the modelling methods that have been used to assess SO{sub 2}, NO{sub 2} and NOx, PM10, benzene and CO concentrations throughout the UK. The dominant contributions to measured SO{sub 2} concentrations in the UK are typically from major point sources such as power stations and refineries, particularly in terms of high percentile concentrations. 39 refs.

  11. Study on the impact of regulation (EC) No 1/2005 on the protec-tion of animals during transport

    NARCIS (Netherlands)

    Baltussen, W.H.M.; Gebrensbet, G.; Roest, de K.

    2011-01-01

    The objective of the findings of an evaluation of Regulation (EC) 1/2005 was to provide a detailed assessment of the implementation of the Regulation (EC) and its impact on the animals being transported and on operators, with special reference to trade flows, navigation systems and the socio‐economi

  12. The history of derogations from chemical parametric values set by the European Drinking Water Directive (Council Directive 98/83/EC), in Italy and the Piedmont region.

    Science.gov (United States)

    Zicari, Giuseppe; Marro, Silvia; Soardo, Vincenzo; Berruti, Renza; Maggi, Claudio; Cerrato, Elena; Ferrari, Romina; Gulino, Margherita

    2014-01-01

    Italian legislation (Article 13 of Legislative Decree 31/2001) provides for the possibility of establishing derogations from chemical parametric values for drinking water set by EU legislation (Council Directive 98/83/EC), if the supply of drinking water cannot be maintained by any other reasonable means. A derogation is possible only after obtaining a specific authorization and must be limited to the shortest time possible. This paper presents the history of derogations granted in Italy and the case of arsenic and nickel in Piedmont. From 2003 to 2009, 13 regions requested a derogation (Campania, Emilia Romagna, Latium, Lombardy, Marche, Piedmont, Apulia, Sardinia, Sicily, Tuscany, Trentino Alto Adige, Umbria, Venetia) at different times and for a total of 13 parameters. In 2012, tap water provided to almost one million Italians in 112 municipalities of three regions (Latium, Tuscany and Campania), did not comply with the legal limits for the following parameters: arsenic, boron and fluorides. Currently, in the Piedmont region there are no derogations from the maximum permitted concentrations of contaminants in drinking water. In the past derogations have been applied for the nickel parameter (years 2006-2007) and from the arsenic parameter (years 2006-2008).

  13. Determination of the priority substances regulated by 2000/60/EC and 2008/105/EC Directives in the surface waters supplying water treatment plants of Athens, Greece.

    Science.gov (United States)

    Golfinopoulos, Spyros K; Nikolaou, Anastasia D; Thomaidis, Nikolaos S; Kotrikla, Anna Maria; Vagi, Maria C; Petsas, Andreas S; Lekkas, Demetris F; Lekkas, Themistokles D

    2017-03-21

    An investigation into the occurrence of priority substances regulated by 2000/60/EC Water Framework Directive and 2008/105/EC Directive was conducted for a period of one year in the surface water sources supplying the water treatment plants (WTPs) of Athens and in the raw water of WTPs. Samples from four reservoirs and four water treatment plants of Athens were taken seasonally. The substances are divided into seven specific groups, including eight volatile organic compounds (VOCs), diethylhexylphthalate, four organochlorine pesticides (OCPs), three organophosphorus/organonitrogen pesticides (OPPs/ONPs), four triazines and phenylurea herbicides, pentachlorophenol, and four metals. The aforementioned substances belong to different chemical categories, and different analytical methods were performed for their determination. The results showed that the surface waters that feed the WTPs of Athens are not burdened with significant levels of toxic substances identified as European Union (EU) priority substances. Atrazine, hexachlorocyclohexane, endosulfan, trifluralin, anthracene and 4-nonylphenol were occasionally observed at very low concentrations. Their presence in a limited number of cases could be attributed to waste disposal, agricultural activities, and to a limited industrial activity in the area nearby the water bodies.

  14. Impact of EC Regulation on Animal Protection during Transport in Romania – some Aspects

    Directory of Open Access Journals (Sweden)

    Ioana Andronie

    2013-10-01

    Full Text Available The aim of this study was to establish how the application of EC Regulation 1/2005 and national legislation, have contributed or not to increase the animal protection and welfare during transport in our country. Short or long distance of animal transport done often in poor conditions can produce suffering of the animal involved. EU and national legislation in the field, wanted that suffering being minimized or even missing. A Commission report on animal transport Regulation showed that current legislation applicable from 2007 made some improvements in this area but it is still far from satisfactory especially in terms of time journey in relation with travel conditions (means of transport construction, microclimate, and methods of loading/unloading, supplies of food and water, stop for watering, feeding and rest. The study was based on answers given by drivers and attendants of animals involved in transport to some questions in the field. Results showed that livestock transporters lined to current legislation requirements thus ensuring the protection and animal welfare. This was due both proper equipping vehicles, especially long-term transport, and training of the drivers and attendants of animals in order to obtain the certificate of competence.

  15. AMENDING REGULATION (EC NO.1346/2000 ON INSOLVENCY PROCEEDINGS - SOLVING DEFICIENCIES OR ATTEMPT TO RESCUE COMPANIES IN DIFFICULTY?

    Directory of Open Access Journals (Sweden)

    GABRIELA FIERBINŢEANU

    2013-05-01

    Full Text Available EC Insolvency Regulation claims, after more than 10 years, several changes imposed by some of the issues raised by the practice of its application but also by the need to promote economic recovery for enterprises in difficulty in the current economic crisis. This paper analyzes the major segments of change and aims to determine whether these segments provide a coherent answer for the practical difficulties faced by the EC Regulation and whether extending its scope by revising the definition of insolvency proceedings may offer better chances of recovery for the enterprises in difficulty.

  16. EFSA guidance on the submission of applications for authorisation of genetically modified plants under Regulation (EC No 1829/2003

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-12-01

    Full Text Available This document provides guidance to applicants for submitting an application for authorisation of genetically modified (GM plants for food and feed uses, import and processing, and/or cultivation in the European Union under Regulation (EC No 1829/2003. The EFSA submission guidance describes the community procedures in the European Union for handling GM plant applications, and provides instructions to applicants on how to prepare and present data in an application. It is supplemented with seven appendices providing templates of data presentation to be followed by applicants, including a completeness checklist. The earlier versions are now updated to account for requirements outlined in Implementing Regulation (EU No 503/2013. Instructions for submission described in this EFSA guidance are applicable to all GM plant applications submitted under Articles 5, 11, 17 and 23 of Regulation (EC No 1829/2003.

  17. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2015. Scientific opinion on the Safety of lacto-N-neotetraose as a novel food ingredient pursuant to Regulation (EC) No 258/97

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on lacto-N-neotetraose as a novel food ingredient (NFI) submitted pursuant to Regulation (EC) No 258/97 of the European Parliament and of the Council......, taking into account the comments and objections of a scientific nature raised by Member States. Lacto-N-neotetraose (LNnT) is a synthetic tetrasaccharide, which is intended to be used in infant and follow-on formulae, foods for special medical purposes for infants and young children and other foods...

  18. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2015. Scientific opinion on the safety of 2'-O-fucosyllactose as a novel food ingredient pursuant to Regulation (EC) No 258/97

    DEFF Research Database (Denmark)

    Tetens, Inge

    2015-01-01

    Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on 2'-O-fucosyllactose as a novel food ingredient (NFI) submitted pursuant to Regulation (EC) No 258/97 of the European Parliament and of the Council......, taking into account the comments and objections of a scientific nature raised by Member States. 2'-O-fucosyllactose (2'-FL) is a synthetic trisaccharide, which is intended to be used in infant and follow-on formulae, foods for special medical purposes for infants and young children, and other foods...

  19. Regulation (EC No 1901/2006 on medicinal products for paediatric use & clinical research in vulnerable populations

    Directory of Open Access Journals (Sweden)

    Lehmann Birka

    2008-12-01

    Full Text Available Abstract Before any medicinal product is authorised for use in adults, it must undergo extensive pharmaceutical consistency and stability tests, toxicological tests and clinical trials to ensure that it is of high quality, safe and effective. The same approach may not always be applied to medicinal products used to treat children. Studies showed that over 50% of the medicinal products used in children may not have been tested for use in this age group. The absence of suitable authorised medicinal products to treat conditions in children results from the fact that pharmaceutical companies do not adapt medicinal products to the needs of the paediatric population. This leaves health care professionals with no alternative other than to use medicinal products "off-label" and to use unauthorised products with the associated risks of inefficacy and/or adverse reactions. The Regulation (EC No 1901/2006 sets up a system of requirements, rewards and incentives, together with horizontal measures, to ensure that medicinal products are researched, developed and authorised to meet the therapeutic needs of children. The Regulation is addressed to: 1. The pharmaceutical industry by setting out the legal framework for receiving rewards and incentives by conducting clinical trials in the paediatric population. 2. The Member States to set out to support research into, and the development and availability of, medicinal products for paediatric use. 3. The Community as funds for research into medicinal products for the paediatric population shall be provided for in the Community budget in order to support studies relating to medicinal products or active substances not covered by a patent or a supplementary protection certificate. The legal framework for conducting clinical trials, including children/minors, is set up in Directive 2001/20/EC, the Clinical Trials Directive (CTD, for the European Union (EU. The CTD establishes specific provisions regarding conduct of

  20. Safety of UV-treated milk as a novel food pursuant to Regulation (EC) No 258/97

    DEFF Research Database (Denmark)

    Poulsen, Morten

    Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on UV-treated milk as a novel food submitted pursuant to Regulation (EC) No 258/97, taking into account the comments and objections of a scientific...... of infants (up to 1 year of age). The Panel considers that it is unlikely that tolerable upper intake levels established by EFSA for children aged 1–10 years, adolescents and adults will be exceeded. The Panel considers that the novel food is not nutritionally disadvantageous. The data provided do not give...... rise to concerns with regard to the microbiological quality. The Panel considers that the risk of allergic reactions to the novel food is not dissimilar to that associated with conventional milk. The Panel concludes that the novel food, UV-treated milk, is safe under the intended conditions of use...

  1. Basic substances under EC 1107/2009 phytochemical regulation: experience with non-biocide and food products as biorationals

    Directory of Open Access Journals (Sweden)

    Marchand Patrice A.

    2016-07-01

    Full Text Available Basic Substances are a newly effective category of Plant Protection Product under EC Regulation No 1107/2009. The first approved application of Equisetum arvense L. opened Part C of Implementing Regulation (EU No 540/2011, which lists the basic substance approved. Although E. arvense was described as a fungicide extract, subsequent applications like chitosan were related to non-biocide molecules. Consequently, plant protection product data were collected from research on alternative or traditional crop protection methods. They are notably issued or derived from foodstuffs (plants, plant by-products, plant derived products, substances and derived substances from animal origin. Applications are currently submitted by our Institute, under evaluation at different stages of the approval process or already approved. Remarkably, this Basic Substance category under pesticide EU Regulation was surprisingly designed for these non-biocidal plant protection products. In fact, components described as the “active substance” of most of the actual applications are food products like sugars and lecithin. Basic Substance applications for these foodstuffs are therefore a straightforward way of easily gaining approval for them. Here we describe the approval context and detail the agricultural uses of theses food products as Biological Control Agents (BCAs or biorationals for crop protection. From all deposited or approved Basic Substance Application (BSA, a proof has been provided that non-biocide and food products via physical barrier or lure effects may be effective plant protection products with an acceptable low profile of concern for public and agricultural safety.

  2. MicroRNA-281 regulates the expression of ecdysone receptor (EcR) isoform B in the silkworm, Bombyx mori

    Science.gov (United States)

    Hundreds of Bombyx mori miRNAs had been identified in recent years, but their function in vivo remains poorly understood. The silkworm EcR gene (BmEcR) has three transcriptional isoforms, A, B1 and B2. Isoform sequences are different in the 3’UTR region of the gene, which is the case only in insects...

  3. 10 CFR 51.10 - Purpose and scope of subpart; application of regulations of Council on Environmental Quality.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Purpose and scope of subpart; application of regulations of Council on Environmental Quality. 51.10 Section 51.10 Energy NUCLEAR REGULATORY COMMISSION..., regulations, and public laws of the United States shall be interpreted and administered in accordance with...

  4. Up-regulation of stathmin induces growth arrest of esophageal squamous cell carcinoma EC9706 cell%上调stathmin基因表达对食管鳞癌EC9706细胞的作用

    Institute of Scientific and Technical Information of China (English)

    王峰; 王留兴; 何炜; 李克; 王瑞林; 赵培荣; 樊青霞

    2010-01-01

    proliferation of transfected cells was measured by cell counting, MTT and in vitro formation assay of flat Flow cytometry was used to detect the cell cycle. Nude mice were adopted to investigate the in vivo tumorigenic characteristics of the transfected cells. Results A 450 bp coding sequence of stathmin cDNA was amplified by RT-PCR and then cloned into pcDNA3. 1 ( + ) plasmid to harvest the recombinant plasmid pcDNA3. 1-stathmin. The recombinant plasmid pcDNA3. 1-stathmin and blank vector were transfected respectively into EC9706 cells. The up-regulated expression of stathmin protein was validated by Western blot ( P < 0. 01 ) . Compared with control, EC9706 cells transfected with pcDNA3. 1-stathmin appeared swollen and multi-nuclear with a cell mitotic arrest; doubling generation time of pcDNA3. 1stathmin transfectants was prolonged(25 -28 h); The in vitro cell proliferation ability and clone formation rate (34.5% +-6.9%) decreased, cell cleavage was blocked at G2/M phase (21. 7% +- 3. 4% ) and the oncogenicity of inoculated cells in nude mice decreased ( all P < 0. 01). Conclusions The up-regulated expression of stathmin protein triggered by the recombinant plasmid pcDNA3. 1-stathmin can inhibit the proliferation and oncogenicity of ESCC EC9706 cells. TTiis molecule may be a promising therapeutic target in ESCC patients.

  5. Medical devices and the Middle East: market, regulation, and reimbursement in Gulf Cooperation Council states

    Directory of Open Access Journals (Sweden)

    Howard JJ

    2014-11-01

    Full Text Available Jason J Howard Division of Paediatric Orthopaedics, Department of Surgery, Sidra Medical and Research Center, Doha, Qatar Abstract: With some of the richest economies in the world, the Gulf Cooperation Council (GCC is undergoing rapid growth not only in its population but also in health care expenditure. Despite the GCC's abundance of hydrocarbon-based wealth, the drivers of the medical device industry in the GCC are still in flux, with gains yet to be made in areas of infrastructure, regulation, and reimbursement. However, the regional disease burden, expanding health insurance penetration, increasing privatization, and a desire to attract skilled expatriate health care providers have led to favorable conditions for the medical device market in the GCC. The purpose of this article is to investigate the current state of the GCC medical device industry, with respect to market, regulation, and reimbursement, paying special attention to the three largest medical device markets: Saudi Arabia, the United Arab Emirates, and Qatar. The GCC would seem to represent fertile ground for the development of medical technologies, especially those in line with the regional health priorities of the respective member states. Keywords: medical devices, regulation, reimbursement, Middle East 

  6. Reasoned opinion on the review of the existing maximum residue levels (MRLs for dichlobenil according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance dichlobenil. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of dichlobenil are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses for the time being but this assessment may be reconsidered when the future review of MRLs for fluopicolide under the aforementioned regulation (EC No 396/2005 will be carried out because fluopicolide is an authorised pesticide active substance generating a metabolite common to dichlobenil.

  7. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the modification of the authorisation of a health claim related to cocoa flavanols and maintenance of normal endotheliumdependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006 following a request in accordance with Article 19 of Regulation (EC) No 1924/2006

    OpenAIRE

    Tetens, Inge

    2014-01-01

    Following an application from Barry Callebaut Belgium NV, submitted pursuant to Article 19 of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the modification of the authorisation of a health claim related to “cocoa flavanols help maintain the elasticity of blood vessels, which contributes to normal blood flow”, pursuant to Article 13(5) of Regulation (EC) No 1924/2006. T...

  8. Scientific Opinion on the modification of the authorisation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006 following a request in accordance with Article 19 of Regulation (EC) No 1924/2006

    OpenAIRE

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)

    2014-01-01

    Following an application from Barry Callebaut Belgium NV, submitted pursuant to Article 19 of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the modification of the authorisation of a health claim related to “cocoa flavanols help maintain the elasticity of blood vessels, which contributes to normal blood flow”, pursuant to Article 13(5) of Regulation (EC) No 1924/2006. T...

  9. Medical devices and the Middle East: market, regulation, and reimbursement in Gulf Cooperation Council states

    Science.gov (United States)

    Howard, Jason J

    2014-01-01

    With some of the richest economies in the world, the Gulf Cooperation Council (GCC) is undergoing rapid growth not only in its population but also in health care expenditure. Despite the GCC’s abundance of hydrocarbon-based wealth, the drivers of the medical device industry in the GCC are still in flux, with gains yet to be made in areas of infrastructure, regulation, and reimbursement. However, the regional disease burden, expanding health insurance penetration, increasing privatization, and a desire to attract skilled expatriate health care providers have led to favorable conditions for the medical device market in the GCC. The purpose of this article is to investigate the current state of the GCC medical device industry, with respect to market, regulation, and reimbursement, paying special attention to the three largest medical device markets: Saudi Arabia, the United Arab Emirates, and Qatar. The GCC would seem to represent fertile ground for the development of medical technologies, especially those in line with the regional health priorities of the respective member states. PMID:25429243

  10. The stimulatory adenosine receptor ADORA2B regulates serotonin (5-HT synthesis and release in oxygen-depleted EC cells in inflammatory bowel disease.

    Directory of Open Access Journals (Sweden)

    Rikard Dammen

    Full Text Available OBJECTIVE: We recently demonstrated that hypoxia, a key feature of IBD, increases enterochromaffin (EC cell 5-HT secretion, which is also physiologically regulated by the ADORA2B mechanoreceptor. Since hypoxia is associated with increased extracellular adenosine, we wanted to examine whether this nucleotide amplifies HIF-1α-mediated 5-HT secretion. DESIGN: The effects of hypoxia were studied on IBD mucosa, isolated IBD-EC cells, isolated normal EC cells and the EC cell tumor derived cell line KRJ-1. Hypoxia (0.5% O2 was compared to NECA (adenosine agonist, MRS1754 (ADORA2B receptor antagonist and SCH442146 (ADORA2A antagonist on HIF signaling and 5-HT secretion. Antisense approaches were used to mechanistically evaluate EC cells in vitro. PCR and western blot were used to analyze transcript and protein levels of HIF-1α signaling and neuroendocrine cell function. An animal model of colitis was evaluated to confirm hypoxia:adenosine signaling in vivo. RESULTS: HIF-1α is upregulated in IBD mucosa and IBD-EC cells, the majority (~90% of which express an activated phenotype in situ. Hypoxia stimulated 5-HT release maximally at 30 mins, an effect amplified by NECA and selectively inhibited by MRS1754, through phosphorylation of TPH-1 and activation of VMAT-1. Transient transfection with Renilla luciferase under hypoxia transcriptional response element (HRE control identified that ADORA2B activated HIF-1α signaling under hypoxic conditions. Additional signaling pathways associated with hypoxia:adenosine included MAP kinase and CREB. Antisense approaches mechanistically confirmed that ADORA2B signaling was linked to these pathways and 5-HT release under hypoxic conditions. Hypoxia:adenosine activation which could be reversed by 5'-ASA treatment was confirmed in a TNBS-model. CONCLUSION: Hypoxia induced 5-HT synthesis and secretion is amplified by ADORA2B signaling via MAPK/CREB and TPH-1 activation. Targeting ADORA2s may decrease EC cell 5-HT

  11. Scientific opinion on the safety of synthetic L-ergothioneine (Ergoneine®) as a novel food pursuant to Regulation (EC) No 258/97

    DEFF Research Database (Denmark)

    Poulsen, Morten

    Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on synthetic l-ergothioneine, marketed as Ergoneine®, as a novel food submitted pursuant to Regulation (EC) No 258/97 of the European...... concerns. The applicant intends to use the novel food in quantities of up to 5 mg per serving in alcohol-free beverages, cereal bars, milk, fresh dairy products and chocolate. The applicant also proposes to provide the novel food as a food supplement, with a daily dose of up to 30 mg/day for adults and 20...

  12. Reasoned opinion on the review of the existing maximum residue levels (MRLs for ethoxyquin according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance ethoxyquin. Although this active substance is no longer authorised within the European Union, an MRL was established by the Codex Alimentarius Commission (CXL. Based on the assessment of the available data, EFSA assessed the CXL, and a consumer risk assessment was carried out. The CXL was found not to be adequately supported by data and a possible risk to consumers was identified. Hence, further consideration by risk managers is needed.

  13. Reasoned opinion on the review of the existing maximum residue levels (MRLs for indolylbutyric acid according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance indolylbutyric acid. Considering that this active substance is not authorised for use on edible crops within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of indolylbutyric acid are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or a limit of quantification (LOQ for enforcement against potential illegal uses.

  14. Reasoned opinion on the review of the existing maximum residue levels (MRLs for acetochlor according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance acetochlor. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of acetochlor are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  15. Reasoned opinion on the review of the existing maximum residue levels (MRLs for cyanamide according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance cyanamide. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of cyanamide are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  16. Reasoned opinion on the review of the existing maximum residue levels (MRLs for trifluralin according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-04-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance trifluralin. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of trifluralin are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  17. Reasoned opinion on the review of the existing maximum residue levels (MRLs for asulam according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance asulam. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of asulam are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  18. Reasoned opinion on the review of the existing maximum residue levels (MRLs for dicloran according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-06-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance dicloran. Although this active substance is no longer authorised within the European Union, MRLs were established by the Codex Alimentarius Commission (CXLs. Based on the assessment of the available data, EFSA assessed the CXLs, and a consumer risk assessment was carried out. Some CXLs were found not to be adequately supported by data and, for some CXLs, a possible acute risk to consumers was also identified. Hence, further consideration by risk managers is needed.

  19. Reasoned opinion on the review of the existing maximum residue levels (MRLs for quinoclamine according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-03-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance quinoclamine. Considering that this active substance is not authorised for use on edible crops within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of quinoclamine are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  20. Reasoned opinion on the review of the existing maximum residue levels (MRLs for guazatine according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance guazatine. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of guazatine are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  1. Reasoned opinion on the review of the existing maximum residue levels (MRLs for propargite according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-08-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance propargite. Although this active substance is no longer authorised within the European Union, MRLs were established by the Codex Alimentarius Commission (CXLs. Based on the assessment of the available data, EFSA assessed the CXLs. CXLs were found not to be adequately supported by data and a consumer risk assessment could not be carried out. Hence, further consideration by risk managers is needed.

  2. Reasoned opinion on the review of the existing maximum residue levels (MRLs for 1,3-dichloropropene according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance 1,3-dichloropropene. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of 1,3-dichloropropene are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive an LOQ for enforcement against potential illegal uses.

  3. Reasoned opinion on the review of the existing maximum residue levels (MRLs for dodemorph according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance dodemorph. Considering that this active substance is not authorised for use on edible crops within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of dodemorph are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  4. Reasoned opinion on the review of the existing maximum residue levels (MRLs for indolylacetic acid according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance indolylacetic acid. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of indolylacetic acid are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or a limit of quantification (LOQ for enforcement against potential illegal uses.

  5. Reasoned opinion on the review of the existing maximum residue levels (MRLs for chloropicrin according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance chloropicrin. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of chloropicrin are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  6. Reasoned opinion on the review of the existing maximum residue levels (MRLs for propisochlor according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-06-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance propisochlor. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of propisochlor are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  7. Scientific Opinion on the safety of alginate-konjac-xanthan polysaccharide complex (PGX) as a novel food pursuant to Regulation (EC) No 258/97

    DEFF Research Database (Denmark)

    Poulsen, Morten

    is an off-white granular powder composed of three non-starch polysaccharides: konjac glucomannan, xanthan gum and sodium alginate. The information provided on the composition, the specifications, the batch-to-batch variability and the stability of the NF is sufficient and does not raise safety concerns......Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on alginate-konjac-xanthan polysaccharide complex (PGX) as a novel food (NF) submitted pursuant to Regulation (EC) No 258/97. The NF...

  8. Directive2001-83-EC关于传统草药的具体规定%Detailed regulations about traditional herbal medicines in Directive 2001-83-EC

    Institute of Scientific and Technical Information of China (English)

    黄宇虹; 张伯礼

    2011-01-01

    Directive 2001-83-EC is a primary part of the EU laws and regulations relevant to drugs used in human.The Directive 2001-83-EC published firstly in Nov.6, 2001 has being used to supervise the manufacture,distribution and administration of medical products in order to protect the public health and promote drug development.Up to date, it has been revised seven times.This article, according to the third part of the Directive 2001-83-EC published in Dec.30.2008, introduces the detailed regulations about traditional herbal registration in EU.The goal is to offer information for Chinese researchers, sponsors and other persons who are interested in registering Chinese traditional medicines in EU and intend to get approval.%2001-83号法令是欧盟人用药物相关法令中的基本大法.该法令于2001年11月6日第一次颁布,主要是用于监管药品生产、流通、使用环节,以保证公众健康和促进药品研发.到目前为止已经修订了7次.本文依据2008年12月30日版中第三大部分内容,详细介绍了传统植物药在欧盟注册的法规要求,以期为国内的研究者、企业(申办者)及其他致力于传统中草药在欧盟注册并期望获得批准的有志者提供些许信息支持.

  9. Reasoned opinion on the review of the existing maximum residue levels (MRLs for methyl bromide according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance methyl bromide. Although this active substance is no longer authorised within the European Union, guideline levels for methyl bromide (at point of retail sale or when offered for consumption and MRLs for bromide ion, which is a relevant metabolite of methyl bromide, were established by the Codex Alimentarius Commission (CXLs. Regarding methyl bromide, the default MRL of 0.01 mg/kg as defined by Regulation (EC No 396/2005 is compliant with the Codex guideline levels and provides a satisfactory level of protection for the European consumer but it could not be demonstrated that the default MRL can be achieved in routine enforcement. Moreover, based on the assessment of the available data, some CXLs were found not to be adequately supported by data and the consumer risk assessment could not be finalised, as the toxicological reference values of bromide ion need to be revised and only few information on the natural occurrence of bromide ion in food was available to EFSA. Hence, further consideration by risk managers is needed.

  10. Reviewing the Nutrition and Health Claims Regulation (EC) No. 1924/2006: What do we know about its challenges and potential impact on innovation?

    Science.gov (United States)

    Bröring, Stefanie; Khedkar, Sukhada; Ciliberti, Stefano

    2017-02-01

    Health claims potentially represent an opportunity for firms to engage in product differentiation and thereby induce investment into R&D and innovation in the food sector. The Nutrition and Health Claims Regulation (EC) No. 1924/2006 (NHCR) aims at protecting and promoting innovation as one of its objectives. However, existing studies indicate that this regulation may create several challenges for innovation in the food sector. To this end, we review the challenges related to the NHCR (Article 13.1) and its impact on innovation. Extant literature suggests that companies face challenges related to changing list of ingredients, missing transparency, wording of claims, limited financial resources, limited R&D resources, switching product categories and abandoning the functional foods sector. Moreover, current studies imply that so far the NHCR (in specific Article 13.1) does not seem to encourage innovation in the EU food sector.

  11. Exploring the Nutrition and Health Claims Regulation (EC) No. 1924/2006: What is the impact on innovation in the EU food sector?

    Science.gov (United States)

    Khedkar, Sukhada; Bröring, Stefanie; Ciliberti, Stefano

    2017-02-01

    Literature suggests that despite its positive aim of promoting innovation, the Nutrition and Health Claims Regulation (EC) No. 1924/2006 (NHCR) may bring along several compliance challenges, which might affect innovation in the EU food sector. This study investigates the challenges faced by companies to comply with the NHCR (specifically Article 13.1) and their impact on innovation. To this end, we conducted an online survey with 105 companies involved in the EU food sector. Results indicate that companies perceive wording of claims, missing transparency and limited financial resources as major challenges to comply with the NHCR (Article 13.1). Companies reported not to have increased their R&D expenditure or innovation activities after the NHCR (Article 13.1) was implemented. Thus, this study highlights specific compliance challenges related to the NHCR (Article 13.1) and indicates that currently, the regulation does not seem to have fostered innovation in the EU food sector.

  12. COUNCIL DECISIONS ON THE 5-YEARLY REMUNERATION REVIEW, AJUSTMENTS FOR 2001 AND CHANGES TO THE STAFF RULES AND REGULATIONS

    CERN Multimedia

    Human Resources Division

    2001-01-01

    As announced by the Director-General in December last year, Council approved the package of measures concerning the 5-yearly remuneration review, recommended by the TREF Restricted Group, as well as the adjustments for 2001 related to salaries and pensions. These measures, as summarised below, enter into force on 1 January 2001, subject to later implementation of some items. Related changes to the Staff Rules and Regulations will be published as soon as possible in the mean time, changes which were annexed to the Council Resolution can be viewed on the HR Division Web site. 1. Scale of basic salaries (Annex R A 1 of the Staff Regulations) : increased by 4.32% resulting from the 5-yearly Review, and by 0.6% which corresponds to the salary adjustment for 2001. This includes the increases in social insurance contributions indicated below. 2. Scale of stipends of Fellows (Annex R A 2 of the Staff Regulations) : increased by 1.52% resulting from the 5-yearly Review, and by 0.6% which corresponds to the adjustment ...

  13. Reasoned opinion on the review of the existing maximum residue levels (MRLs for kresoxim-methyl according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance kresoxim-methyl. In order to assess the occurrence of kresoxim-methyl residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  14. Reasoned opinion on the review of the existing maximum residue levels (MRLs for fenhexamid according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance fenhexamid. In order to assess the occurrence of fenhexamid residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  15. Reasoned opinion on the review of the existing maximum residue levels (MRLs for boscalid according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance boscalid. In order to assess the occurrence of boscalid residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and all MRL proposals derived by EFSA still require further consideration by risk managers

  16. Reasoned opinion on the review of the existing maximum residue levels (MRLs for flutolanil according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-09-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance flutolanil. In order to assess the occurrence of flutolanil residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still requires further consideration by risk managers.

  17. Reasoned opinion on the review of the existing maximum residue levels (MRLs for etoxazole according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-10-01

    Full Text Available

    According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance etoxazole. In order to assess the occurrence of etoxazole residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  18. Reasoned Opinion on the review of the existing maximum residue levels (MRLs for trifloxystrobin according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-02-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance trifloxystrobin. In order to assess the occurrence of trifloxystrobin residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  19. Reasoned opinion on the review of the existing maximum residue levels (MRLs for azoxystrobin according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-12-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance azoxystrobin. In order to assess the occurrence of azoxystrobin residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances andEuropean authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  20. Reasoned opinion on the review of the existing maximum residue levels (MRLs for folpet according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-05-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance folpet. In order to assess the occurrence of folpet residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  1. Reasoned opinion on the review of the existing maximum residue levels (MRLs for teflubenzuron according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-04-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance teflubenzuron. In order to assess the occurrence of teflubenzuron residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  2. Reasoned opinion on the review of the existing maximum residue levels (MRLs for fenamidone according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-11-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance fenamidone. In order to assess the occurrence of fenamidone residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  3. Reasoned opinion on the review of the existing maximum residue levels (MRLs for metsulfuron-methyl according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance metsulfuron-methyl. In order to assess the occurrence of metsulfuron-methyl residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  4. Reasoned opinion on the review of the existing maximum residue levels (MRLs for thiabendazole according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-07-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance thiabendazole. In order to assess the occurrence of thiabendazole residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and all MRL proposals derived by EFSA still require further consideration by risk managers.

  5. Reasoned opinion on the review of the existing maximum residue levels (MRLs for flurtamone according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-12-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance flurtamone. In order to assess the occurrence of flurtamone residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. No information required by the regulatory framework was found to be missing and no risk to consumers was identified.

  6. Reasoned opinion on the review of the existing maximum residue levels (MRLs for carfentrazone-ethyl according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-11-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance carfentrazone-ethyl. In order to assess the occurrence of carfentrazone-ethyl residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and all MRL proposals derived by EFSA still require further consideration by risk managers.

  7. Reasoned opinion on the review of the existing maximum residue levels (MRLs for acibenzolar-S-methyl according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-02-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide acibenzolar-S-methyl. In order to assess the occurrence of acibenzolar-S-methyl residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  8. Reasoned opinion on the review of the existing maximum residue levels (MRLs for mesosulfuron according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-11-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance mesosulfuron. In order to assess the occurrence of mesosulfuron residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. No information required by the regulatory framework was found to be missing and no risk to consumers was identified.

  9. Reasoned opinion on the review of the existing maximum residue levels (MRLs for cyazofamid according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-12-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide cyazofamid. In order to assess the occurrence of cyazofamid residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory framework was found to be missing. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  10. The draft EC sewage sludge regulation and its consequences for sewage sludge management; EU-Klaerschlamm-Richtlinie (Entwurf) und deren Auswirkungen auf die Praxis der Klaerschlammentsorgung

    Energy Technology Data Exchange (ETDEWEB)

    Schmelz, K.G.; Wolf, R. [Emschergenossenschaft und Lippeverband, Essen (Germany); Esch, B. [Abwassertechnische Vereinigung e.V. (ATV), Hennef (Germany)

    2001-07-01

    The new EC regulation favours the utilization of sewage sludge as an agricultural fertilizer. There will be two categories of sludge, i.e. hygienized and conventionally treated sludge, and apart from fields also other agricultural lands will be listed as land where dumping of sewage is permissible. Maximum permissible heavy metal concentrations will be set at 25% of the present values, and limiting values will be defined also for organic pollutants (LAS, DEHP; NPE, PAH) although the latter are not yet scientifically proved to be hazardous. In view of the intention of the new EC regulation, i.e. promoting the use of sewage sludge as an agricultural fertilizer, the authors make some critical comments, especially on the more rigid limiting values, the introduction of new limiting values without scientific validation, the favouring of hygienization processes, and the frequency of control analyses. [German] Die EU-Kommission hat im April des letzten Jahres den 3. Arbeitsentwurf zur Novellierung der europaeischen Klaerschlammrichtlinie vorgelegt. Das Ziel der Richtlinie ist eindeutig die Foerderung der landwirtschaftlichen Klaerschlammverwertung. Nach den Vorstellungen der EU-Kommission soll es zukuenftig zwei Klassen von Klaerschlaemmen geben, die sich in der Behandlung (Klasse 1: Mit Hygienisierung, Klasse 2: Konventionelle Behandlung) und den zugelassenen Ausbringungsflaechen bzw. den Einschraenkungen der Ausbringung unterscheiden. Als Ausbringungsflaechen werden neben Ackerland auch Weideland, Futter-, Obst-, Gemuese- und Weinanbauflaechen, Baumschulen, Rekultivierungsflaechen und oeffentliche Gruenflaechen wie Parks etc. zugelassen. Neben der stufenweisen Absenkung der Schwermetallgehalte auf bis zu 25% der Werte der zur Zeit in Deutschland gueltigen Klaerschlammverordnung (AbfKlaerV) sollen Konzentrationsgrenzwerte fuer zusaetzliche organische Schadstoffe (LAS, DEHP, NPE, PAH) aufgenommen werden. Ein wissenschaftlich fundierter Nachweis der Schaedlichkeit dieser

  11. The Italian Helpdesk under the Regulation (EC No. 1272/2008 (CLP: three-year activity and experience (2009-2011

    Directory of Open Access Journals (Sweden)

    Sonia D'Ilio

    2012-01-01

    Full Text Available INTRODUCTION: The Regulation (EC No. 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP sets further obligations for manufacturers, importers, distributors, downstream users of substances either on their own or in mixtures. According to the European mandate, each Member State has constituted its National Helpdesk to provide advice to the interested parties on their duties under this Regulation. In Italy, the contact point for questions has been established at the National Centre for Chemical Substances of the Istituto Superiore di Sanità. FUNCTIONS: The responders of the Italian CLP Helpdesk process the requests that have been submitted by the dedicated website. Applicants are asked to complete the form with all the required information. The Helpdesk staff also take part in the European network of CLP, REACH and ECHA Helpdesks together with the European Commission and other parties, that is the HelpNet. RESULTS: The present paper describes the results of the three-year activity of the Italian CLP Helpdesk (2009-2011.

  12. Electric Arc Furnace as a Source of Emission of Polychlorinated Dibenzo-p-Dioxins and Polychlorinated Dibenzofurans in Perspective of the Council Directive 96/61 EC Concerning Integrated Pollution Prevention and Control

    Directory of Open Access Journals (Sweden)

    Sofilić, T.

    2008-01-01

    Full Text Available As the accumulation of PCDDs/Fs in the natural environment poses a great threat, and the pollution of the environment with these highly toxic compounds from various emitters needs to be prevented, many countries have conducted an inventory of industrial sources and their emissions in order to obtain better insight into the share of particular sources in the total emission of PCDDs/Fs and to develop strategies to reduce these emissions.Metallurgical processes like sintering of iron ore, production of steel and non-ferrous and light metals from scrap material belong to a group of stationary PCDDs/Fs emitters and their share in the total PCDDs/Fs emission into the environment is very significant. The relative significance of particular metallurgical processes varies from country to country, depending on the nature of a particular process, installed capacities and annual output levels.As the modern approach to observing the environment includes preventive measures, as opposed to corrective post-event measures that were common practice in the past, the owners/operators of metallurgical processes are developing and introducing pollution monitoring and surveillance systems, based on which they take appropriate measures.One of the frequently applied measures is to build and implement the ISO 14001 environmental management system that very efficiently runs production processes along with maintenance of environmental protection on a daily basis. Since the adoption of the ISO 14001 environmental management system is a voluntary decision to be made by each organization, in 1996 the European Union adopted, for the purpose of environmental protection and pollution prevention, the Directive 96/61 EC or IPPC Directive on Integrated Pollution Prevention and Control (IPPC requiring from industrial installations, depending on their type and output level, to obtain environmental permits to run production processes using best available techniques, thus maintaining

  13. Scientific Opinion on the modification of the authorisation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5 of Regulation (EC No 1924/2006 following a request in accordance with Article 19 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-05-01

    Full Text Available Following an application from Barry Callebaut Belgium NV, submitted pursuant to Article 19 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the modification of the authorisation of a health claim related to “cocoa flavanols help maintain the elasticity of blood vessels, which contributes to normal blood flow”, pursuant to Article 13(5 of Regulation (EC No 1924/2006. The modification concerns an extension of the authorised conditions of use of the claim to a high-flavanols (HF cocoa extract to be consumed in capsules, tablets or added to “other foods, including beverages”. Cocoa flavanols, which are the subject of the health claim, have been sufficiently characterised. Maintenance of normal endothelium-dependent vasodilation is a beneficial physiological effect. The Panel concludes that a cause and effect relationship has been established between the consumption of cocoa flavanols in the HF cocoa extract (i.e. in capsules or tablets and maintenance of normal endothelium-dependent vasodilation. In order to obtain the claimed effect, 200 mg of cocoa flavanols should be consumed daily. This amount could be provided by less than one gram of HF cocoa extract in capsules or tablets, and can be consumed in the context of a balanced diet. The target population is the general population.

  14. Reasoned opinion on the review of the existing maximum residue levels (MRLs for for glufosinate according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2015-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance glufosinate. In order to assess the occurrence of glufosinateresidues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, some MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  15. Reasoned Opinion on the review of the existing maximum residue levels (MRLs for thiacloprid according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-03-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance thiacloprid. In order to assess the occurrence of thiacloprid residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, some MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  16. Reasoned opinion on the review of the existing maximum residue levels (MRLs for pirimiphos-methyl according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2015-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance pirimiphos-methyl. In order to assess the occurrence of pirimiphos-methyl residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible chronic risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, all MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  17. Reasoned opinion on the review of the existing maximum residue levels (MRLs for flusilazole according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-04-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance flusilazole. In order to assess the occurrence of flusilazole residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, some MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  18. Reasoned opinion on the review of the existing maximum residue levels (MRLs for methoxyfenozide according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance methoxyfenozide. In order to assess the occurrence of methoxyfenozide residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified regarding the European authorisations, some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified for some of the MRLs established by the Codex Alimentarius Commission. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further consideration by risk managers.

  19. Reasoned opinion on the review of the existing maximum residue levels (MRLs for propamocarb according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2013-04-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance propamocarb. In order to assess the occurrence of propamocarb residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, some MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  20. Reasoned opinion on the review of the existing maximum residue levels (MRLs for captan according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-04-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance captan. In order to assess the occurrence of captan residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, some MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  1. Reasoned opinion on the review of the existing maximum residue levels (MRLs for chlorothalonil according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-10-01

    Full Text Available

    According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance chlorothalonil. In order to assess the occurrence of chlorothalonil residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals for parent chlorothalonil in plant commodities and for 2,5,6-trichloro-4-hydroxyphtalonitrile (SDS-3701 in animal commodities were derived, and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing (in particular with regard to metabolite SDS-3701 and a possible acute risk to consumers was identified for parent chlorothalonil. Hence, the consumer risk assessment is considered indicative only, all MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  2. Reasoned opinion on the review of the existing maximum residue levels (MRLs for lambda-cyhalothrin according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-01-01

    Full Text Available According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance lambda-cyhalothrin. In order to assess the occurrence of lambda-cyhalothrin residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission as well as the import tolerances and European authorisations reported by Member States (incl. the supporting residues data. Based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Some information required by the regulatory framework was found to be missing and a possible acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, some MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.

  3. Report: Wells Band Council Needs to Improve Its Accounting System to Comply With Federal Regulations

    Science.gov (United States)

    Report #14-2-0316, July 14, 2014. The Wells Band Council’s accounting system did not comply with federal regulations, which resulted in $390,000 of questioned costs and proposed high-risk designation for the grantee.

  4. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014 . Scientific Opinion on the substantiation of a health claim related to zinc and normal growth pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...

  5. EC declaration of conformity.

    Science.gov (United States)

    Donawa, M E

    1996-05-01

    The CE-marking procedure requires that manufacturers draw up a written declaration of conformity before placing their products on the market. However, some companies do not realize that this is a requirement for all devices. Also, there is no detailed information concerning the contents and format of the EC declaration of conformity in the medical device Directives or in EC guidance documentation. This article will discuss some important aspects of the EC declaration of conformity and some of the guidance that is available on its contents and format.

  6. Scientific Opinion on the substantiation of a health claim related to caffeine and increased alertness pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-02-01

    Full Text Available Following an application from SmithKline Beecham Limited, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of United Kingdom, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to caffeine and increased alertness. The food constituent, caffeine, which is the subject of the health claim, is sufficiently characterised. Increased alertness might be a beneficial physiological effect. A claim on caffeine and increased alertness, in the general adult population, for products containing at least 75 mg of caffeine per serving, has already been assessed by the Panel with a favourable outcome. In the present application, the applicant proposed that, in order to bear the claim, a product should contain at least 40 mg of caffeine per serving. In weighing the evidence, the Panel took into account that most studies which measured reaction time in various cognitive tasks found no effect of caffeine at doses < 75 mg. In the particular dose range between 40 and < 75 mg, no effect of caffeine was found on the majority of outcome measures of reaction time. The Panel notes that the majority of studies with caffeine doses of 75 mg or higher showed a significant reduction in measures of reaction time. On the basis of the evidence provided, the Panel reiterates its previous conclusion that, in order to bear the claim, a product should contain at least 75 mg caffeine per serving. The Panel concludes that a cause and effect relationship has not been established between the consumption of caffeine and increased alertness under the conditions of use proposed by the applicant.

  7. Local IWRM organizations for groundwater regulation: The experiences of the Aquifer Management Councils (COTAS) in Guanajuato, Mexico

    NARCIS (Netherlands)

    Wester, P.; Hoogesteger van Dijk, J.D.; Vincent, L.F.

    2009-01-01

    Evidence of groundwater management by aquifer users emerging under Integrated Water Resources Management (IWRM) initiatives is presented, by analyzing the Consejos Técnicos de Aguas (COTAS; Technical Water Councils or Aquifer Management Councils) in the state of Guanajuato, Mexico, established

  8. Trop-2表达下调对食管鳞癌EC9706细胞增殖和细胞迁移的影响%Down-regulation of Trop-2 expression inhibits cell proliferation and migration in human esophageal squamous cell carcinoma cell line EC9706

    Institute of Scientific and Technical Information of China (English)

    李慎柯; 范天黎; 寇洁; 崔瑶

    2011-01-01

    目的:研究肿瘤相关钙信号传导蛋白2(tumorassociated calcium signal transducer-2,Trop-2)表达下调对食管鳞癌EC9706细胞增殖和细胞迁移的影响,并探讨其可能的分子机制.方法:将Trop-2 siRNA和对照siRNA转染食管鳞癌EC9706细胞,利用实时荧光定量PCR和Western blotting检测转染Trop-2 siRNA后食管鳞癌EC9706细胞中Trop-2 mRNA和蛋白的表达.利用CCK-8试剂分析转染Trop-2 siRNA后EC9706细胞的增殖变化,接着采用Boyden小室研究下调Trop-2对EC9706细胞迁移的影响,最后利用Western blotting技术分析与细胞迁移相关基因MMP-7表达的变化.结果:转染Trop-2 48 h,Trop-2 siRNA组中Trop-2 mRNA和蛋白的表达显著低于未处理组和对照siRNA组(P<0.05).Trop-2表达下调能明显抑制食管鳞癌EC9706细胞的增殖(P<0.05).此外,Boyden小室结果表明,与未处理组(119.27±4.63)及对照siRNA组(112.81±5.01)相比,Trop-2 siRNA组中EC9706细胞的穿膜数(65.29±4.33)明显降低.Westernblotting结果表明,Trop-2 siRNA能明显降低食管鳞癌EC9706细胞中MMP-7的表达.结论:Trop-2表达下调能抑制食管鳞癌细胞的增殖和迁移,其介导的迁移能力的降低可能与MMP-7表达的下调密切相关,操纵Trop-2有望成为食管鳞癌的分子治疗靶点.%AIM: To investigate the effect of down-regulation of tumor-associated calcium signal trans-ducer-2 (Trop-2) expression on cell proliferation and migration in human esophageal squamous cell carcinoma (ESCC cell line EC9706 and to explore possible molecular mechanisms involved.METHODS: Trop-2-specific small interferingRNA (siRNA) and control siRNA were transfect-ed into EC9706 cells, and expression of Trop-2 mRNA and protein was detected by real-time PCR and Western blotting. CCK-8 assay was used to measure cell proliferation, and Boyden chamber assay was utilized to determine cell migration. The expression of cell migration-related MMP-7 protein was detected by Western blotting

  9. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2016. Scientific opinion on the safety of fermented soybean extract NSK-SD® as a novel food pursuant to Regulation (EC) No 258/97

    DEFF Research Database (Denmark)

    Poulsen, Morten

    Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the fermented soybean extract NSK-SD® as a novel food (NF) submitted pursuant to Regulation (EC) No 258/97 of the European Parliament and of the ......Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the fermented soybean extract NSK-SD® as a novel food (NF) submitted pursuant to Regulation (EC) No 258/97 of the European Parliament...... pregnant and lactating women. The Panel noted that nattokinase exhibits in vitro fibrinolytic activity and in vivo thrombolytic activity in animals when administered parenterally. However, the information provided with respect to absorption, distribution, metabolism and excretion of the NF does not allow...

  10. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to iron and maintenance of normal hair growth pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Pierre Fabre Dermo-Cosmétique, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a hea......Following an application from Pierre Fabre Dermo-Cosmétique, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation...... of a health claim based on newly developed scientific evidence related to iron and maintenance of normal hair growth. Iron is sufficiently characterised. The claimed effect is “reduction of excessive hair loss”. The target population proposed by the applicant is non-menopausal women, aged between 19 and 49...

  11. E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.

    Science.gov (United States)

    Bardaweel, Sanaa; Ghosh, Brahma; Chou, Tsui-Fen; Sadowsky, Michael J; Wagner, Carston R

    2011-01-01

    Histidine triad nucleotide binding proteins (Hints) are highly conserved members of the histidine triad (HIT) protein superfamily. Hints comprise the most ancient branch of this superfamily and can be found in Archaea, Bacteria, and Eukaryota. Prokaryotic genomes, including a wide diversity of both gram-negative and gram-positive bacteria, typically have one Hint gene encoded by hinT (ycfF in E. coli). Despite their ubiquity, the foundational reason for the wide-spread conservation of Hints across all kingdoms of life remains a mystery. In this study, we used a combination of phenotypic screening and complementation analyses with wild-type and hinT knock-out Escherichia coli strains to show that catalytically active ecHinT is required in E. coli for growth on D-alanine as a sole carbon source. We demonstrate that the expression of catalytically active ecHinT is essential for the activity of the enzyme D-alanine dehydrogenase (DadA) (equivalent to D-amino acid oxidase in eukaryotes), a necessary component of the D-alanine catabolic pathway. Site-directed mutagenesis studies revealed that catalytically active C-terminal mutants of ecHinT are unable to activate DadA activity. In addition, we have designed and synthesized the first cell-permeable inhibitor of ecHinT and demonstrated that the wild-type E. coli treated with the inhibitor exhibited the same phenotype observed for the hinT knock-out strain. These results reveal that the catalytic activity and structure of ecHinT is essential for DadA function and therefore alanine metabolism in E. coli. Moreover, they provide the first biochemical evidence linking the catalytic activity of this ubiquitous protein to the biological function of Hints in Escherichia coli.

  12. E. coli histidine triad nucleotide binding protein 1 (ecHinT is a catalytic regulator of D-alanine dehydrogenase (DadA activity in vivo.

    Directory of Open Access Journals (Sweden)

    Sanaa Bardaweel

    Full Text Available Histidine triad nucleotide binding proteins (Hints are highly conserved members of the histidine triad (HIT protein superfamily. Hints comprise the most ancient branch of this superfamily and can be found in Archaea, Bacteria, and Eukaryota. Prokaryotic genomes, including a wide diversity of both gram-negative and gram-positive bacteria, typically have one Hint gene encoded by hinT (ycfF in E. coli. Despite their ubiquity, the foundational reason for the wide-spread conservation of Hints across all kingdoms of life remains a mystery. In this study, we used a combination of phenotypic screening and complementation analyses with wild-type and hinT knock-out Escherichia coli strains to show that catalytically active ecHinT is required in E. coli for growth on D-alanine as a sole carbon source. We demonstrate that the expression of catalytically active ecHinT is essential for the activity of the enzyme D-alanine dehydrogenase (DadA (equivalent to D-amino acid oxidase in eukaryotes, a necessary component of the D-alanine catabolic pathway. Site-directed mutagenesis studies revealed that catalytically active C-terminal mutants of ecHinT are unable to activate DadA activity. In addition, we have designed and synthesized the first cell-permeable inhibitor of ecHinT and demonstrated that the wild-type E. coli treated with the inhibitor exhibited the same phenotype observed for the hinT knock-out strain. These results reveal that the catalytic activity and structure of ecHinT is essential for DadA function and therefore alanine metabolism in E. coli. Moreover, they provide the first biochemical evidence linking the catalytic activity of this ubiquitous protein to the biological function of Hints in Escherichia coli.

  13. Programming Amazon EC2

    CERN Document Server

    Vliet, Jurg

    2011-01-01

    If you plan to use Amazon Web Services to run applications in the cloud, the end-to-end approach in this book will save you needless trial and error. You'll find practical guidelines for designing and building applications with Amazon Elastic Compute Cloud (EC2) and a host of supporting AWS tools, with a focus on critical issues such as load balancing, monitoring, and automation. How do you move an existing application to AWS, or design your application so that it scales effectively? How much storage will you require? Programming Amazon EC2 not only helps you get started, it will also keep y

  14. Works Councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne; Markey, Ray

    2002-01-01

    The article outlines the operation of works councils in Europe and in the context of disscussing their viability in Austalia.......The article outlines the operation of works councils in Europe and in the context of disscussing their viability in Austalia....

  15. Scientific Opinion on the substantiation of health claims related to glycaemic carbohydrates and maintenance of normal brain function pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    OpenAIRE

    Tetens, Inge

    2015-01-01

    Following applications from Dextro Energy GmbH & Co. KG, submitted for the authorisation of health claims pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of health claims related to glycaemic carbohydrates and maintenance of normal brain function. The scope of the applications was proposed to fall under health...

  16. Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    OpenAIRE

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)

    2012-01-01

    Following an application from Barry Callebaut Belgium nv, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation. Cocoa flavanols are sufficiently characterised. The claimed effect is “help maintain end...

  17. Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    OpenAIRE

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)

    2012-01-01

    Following an application from Barry Callebaut Belgium nv, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation. Cocoa flavanols are sufficiently characterised. The claimed effect is “help maintain end...

  18. EVALUATION OF THE FIRST YEAR OF APPLICATION OF THREE-YEAR REGIONAL INTEGRATED PLAN OF CONTROLS (2008/2010 IN LAZIO REGION (REGULATION EC 882/2004

    Directory of Open Access Journals (Sweden)

    S. Saccares

    2011-01-01

    Full Text Available The evaluation of the first year of the three-year Regional Integrated Plan of Controls has highlighted some problems that does not allow, in some cases, to perform risk assessments to different production processes. Evidence of these concerns has allowed to analyze the corrective actions to be applied in order to make the plan appropiate for the purposes intended by the EC.

  19. Owners responsibility of refrigeration equipment according F-Gas-regulation 'EC 842/2006' and answers; Betreiberpflichten nach 'F-Gas-Verordnung' EG 842/2006 und Antworten darauf

    Energy Technology Data Exchange (ETDEWEB)

    Beermann, Karsten [IKKE gGmbH, Duisburg (Germany)

    2012-08-15

    The results of the F-Gas-regulation EC 842/2006 are some responsibilities for owners of refrigeration equipment. To fulfill these duties exist e-learning training modules and different tools which are the result of a European LEONARDO- project. Particularly the awareness of the equipment owner and the certified person (refrigeration technician) according the regulation will be the main background of a safe handling of refrigerants for an effective environmental protection. Interested persons and companies will find helpful information to learn good practice. (orig.)

  20. Council Districts

    Data.gov (United States)

    Town of Cary, North Carolina — View the location of the Town of Cary’s four Town Council districts.Please note that one district, District A, is split into two geo-spatial areas. One area is in...

  1. EC Bananarama 1992

    OpenAIRE

    Borrell, Brent; Maw-Cheng Yang

    1990-01-01

    The disparate banana import policies currently operating in member states of the European Community (EC) are inconsistent with the Community's objective of full economic integration in 1992. Under separate national legislation, widely varying banana prices apply across different member states, varying duties and import quotas apply to the external (world) market, and internal trade is virtually excluded. The inconsistencies are obvious and politically they are highly transparent. Community im...

  2. EC-CERN Memorandum of Understanding (MoU) signature

    CERN Multimedia

    EC audiovisual service

    2009-01-01

    Signature of the Memorandum of Understanding EC-CERN at Brussels with Mr. José Manuel Silva Rodriguez, European Commission Director General for Research , Rolf Heuer, CERN’s Director-General and Torsten Akesson, President of the CERN Council

  3. Statutory regulation and workers' competence: the influence of Dutch works councils on the introduction of new technology

    NARCIS (Netherlands)

    Tijdens, K.; van Klaveren, M.

    1997-01-01

    A repeated survey carried out among Dutch works councils revealed a lower degree of involvement in technological decisionmaking than four years earlier, as well as a lower perception of their influence. In all probability, decreased influence related to decreased attention. Their statutory rights

  4. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to phaseolamine and reduction in body weight (ID 1701) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to phaseolamine and reduction in body weight. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food...

  5. Scientific Opinion on the substantiation of a health claim related to “native chicory inulin” and maintenance of normal defecation by increasing stool frequency pursuant to Article 13.5 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from BENEO-Orafti S.A., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health...... the claimed effect. The Panel concludes that a cause and effect relationship has been established between the consumption of “native chicory inulin” and maintenance of normal defecation by increasing stool frequency. The following wording reflects the scientific evidence: “Chicory inulin contributes...

  6. Scientific Opinion on the substantiation of a health claim related to glycaemic carbohydrates and contribution to normal cognitive function pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Dextro Energy GmbH & Co. KG, submitted for the authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver...... an opinion on the scientific substantiation of a health claim related to glycaemic carbohydrates and contribution to normal cognitive function. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The Panel considers that the food constituent...

  7. Scientific Opinion on the substantiation of a health claim related to “L-tug lycopene” and reduction of blood LDL-cholesterol pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Lycotec Ltd, submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health...... the risk of CHD. The Panel notes that the unpublished studies submitted to support the claim were exploratory in nature and insufficient information was provided to allow the scientific evaluation of these studies. The Panel concludes that a cause and effect relationship has not been established between...

  8. Scientific Opinion on the substantiation of a health claim related to FRUIT UP® and a reduction of post-prandial blood glucose responses pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from WILD-Valencia SAU, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Spain, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion...... on the scientific substantiation of a health claim related to FRUIT UP® and a reduction of post-prandial blood glucose responses. The Panel considers that the food, FRUIT UP®, and the food (i.e. glucose, sucrose) that FRUIT UP® should replace in foods or beverages are both sufficiently characterised in relation...

  9. Council Session

    CERN Multimedia

    1977-01-01

    From face, 1st raw: Erich Lohrmann, Sergio Fubini, Léon Van Hove, John Adams (Directors-General), Paul Levaux (President of the Council) Hans-Otto Wüster, Franco Bonaudi, Robert Lévy-Mandel and 2nd raw, centre: Patrick Mollet, Eliane de Modzelewska, Jean-Marie Dufour

  10. Use of the EFSA Standard Sample Description (SSD for the reporting of data on the control of pesticide residues in food and feed according to Regulation (EC No 396/2005 (Version: 2013 Data Collection

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2014-01-01

    Full Text Available Regulation (EC No 396/2005 on Maximum Residue Levels of pesticides in or on food and feed of plant and animal origin requires the Member States to monitor pesticide residue levels in food commodities and submit the monitoring results to EFSA and the European Commission. In 2009, EFSA developed the Standard Sample Description (SSD, which is a standardised model for the reporting of harmonised data on analytical measurements of chemical substances occurring in food, feed and water. This document is intended to provide the Member States with specific guidance on how to use the SSD for the reporting of the national results of the pesticide monitoring in the framework of Article 32 of Regulation (EC No 396/2005. In particular, this document is meant to provide SSD users with support in selecting the appropriate codes for the elements which pertain to pesticide residues monitoring data. This document shall complement the EFSA guidance document “Standard sample description for food and feed”.

  11. Scientific Opinion on a request from the European Commission related to the emergency measure notified by Luxembourg on genetically modified maize MON 810 according to Article 34 of Regulation (EC No 1829/2003

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Genetically Modified Organisms (GMO

    2013-09-01

    Full Text Available Following a request of the European Commission, the European Food Safety Authority’s Panel on Genetically Modified Organisms (EFSA GMO Panel evaluated the documentation submitted by Luxembourg in support of its request for the prohibition of the placing on the market of the genetically modified maize MON 810 according to Article 34 of Regulation (EC No 1829/2003. All concerns related to human and animal health or the environment raised by Luxembourg were already addressed in previous scientific opinions of the EFSA GMO Panel on maize MON 810 while other concerns relate to socio-economic aspects and co-existence and thus fall outside the remit of EFSA. Therefore, the EFSA GMO Panel concludes that, based on the documentation submitted by Luxembourg, there is no specific scientific evidence, in terms of risk to human and animal health or the environment, that would support the notification of an emergency measure under Article 34 of Regulation (EC No 1829/2003 and that would invalidate its previous risk assessments of maize MON 810.

  12. Scientific Opinion on a request from the European Commission related to the emergency measure notified by Italy on genetically modified maize MON 810 according to Article 34 of Regulation (EC No 1829/2003

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Genetically Modified Organisms (GMO

    2013-09-01

    Full Text Available Following a request of the European Commission, the European Food Safety Authority’s Panel on Genetically Modified Organisms (EFSA GMO Panel evaluated the documentation submitted by Italy in support of its request for the prohibition of the placing on the market of the genetically modified maize MON 810 according to Article 34 of Regulation (EC No 1829/2003. All concerns related to human and animal health or the environment raised by Italy were already addressed in previous scientific opinions of the EFSA GMO Panel on maize MON 810 while other concerns relate to co-existence and thus fall outside the remit of EFSA. Therefore, the EFSA GMO Panel concludes that, based on the documentation submitted by Italy, there is no specific scientific evidence, in terms of risk to human and animal health or the environment, that would support the notification of an emergency measure under Article 34 of Regulation (EC No 1829/2003 and that would invalidate its previous risk assessments of maize MON 810.

  13. Council dinner

    CERN Multimedia

    1980-01-01

    Jean Teillac (President of the Council) gives the speech. The occasion was the end-of-term of Leon Van Hove and John Adams as Research and Executive Director-General, respectively, to be succeeded by Herwig Schopper. The venue was the Hotel Beau-Rivage in Geneva. Beside Jean Teillac are (on the left) G.H. Stafford and Mme Van Hove, (on the right) Mme Schopper.

  14. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2015. Scientific opinion on biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    2015-01-01

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked......-yielding metabolism applies to all ages, including infants and young children (from birth to three years). The Panel concludes that a cause and effect relationship has been established between the dietary intake of biotin and contribution to normal energy-yielding metabolism. The following wording reflects...... the scientific evidence: ‘Biotin contributes to normal energy-yielding metabolism.’ The target population is infants and young children up to three years of age....

  15. Reasoned opinion on the review of the existing maximum residue levels (MRLs for petroleum oils (CAS 92062-35-6 according to Article 12 of Regulation (EC No 396/2005

    Directory of Open Access Journals (Sweden)

    European Food Safety Authority

    2012-07-01

    Full Text Available

    According to Article 12 of Regulation (EC No 396/2005, the European Food Safety Authority (EFSA has reviewed the Maximum Residue Levels (MRLs currently established at European level for the pesticide active substance petroleum oils (CAS 92062-35-6. Considering that this active substance is no longer authorised within the European Union, that no MRLs are established by the Codex Alimentarius Commission, and that no import tolerances were notified to EFSA, residues of petroleum oils (CAS 92062-35-6 are not expected to occur in any plant or animal commodity. Available data were also not sufficient to derive a residue definition or an LOQ for enforcement against potential illegal uses.

  16. Scientific Opinion on the substantiation of a health claim related to hyaluronic acid and protection of the skin against dehydration pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to hyaluronic acid and protection of the skin against dehydration. The food constituent that is the subject of the health claim, hyaluronic acid, is sufficiently characterised. The claimed effect, protection of the skin against dehydration, is a beneficial physiological effect. The target population proposed by the applicant is the general population. No human studies have been provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect relationship has not been established between the consumption of hyaluronic acid and protection of the skin against dehydration.

  17. Scientific Opinion on the substantiation of a health claim related to iodine and contribution to normal thyroid function pursuant to Article 14 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-01-01

    Full Text Available Following an application from Specialised Nutrition Europe (formerly IDACE, submitted pursuant to Article 14 of Regulation (EC No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to iodine and contribution to normal thyroid function. The food constituent, iodine, which is the subject of the health claim, is sufficiently characterised. Contribution to normal thyroid function is a beneficial physiological effect for infants and young children. A claim on iodine and normal thyroid function in the general population has already been assessed with a favourable outcome. The Panel considers that the role of iodine on normal thyroid function applies to all ages, including infants and young children (from birth to three years. The Panel concludes that a cause and effect relationship has been established between the dietary intake of iodine and contribution to normal thyroid function.

  18. Scientific Opinion on the substantiation of a health claim related to ♀EFAX™ and reduction of menstrual discomfort pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-02-01

    Full Text Available Following an application from Nutrilinks Sarl submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Cyprus, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to ♀EFAX™ and reduction of menstrual discomfort. The food, ♀EFAX™, which is standardised pure krill oil and is the subject of the health claim, is sufficiently characterised. The claimed effect, reduction of menstrual discomfort, is a beneficial physiological effect. No human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim were provided by the applicant. A cause and effect relationship has not been established between the consumption of ♀EFAX™ and reduction of menstrual discomfort.

  19. Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-01-01

    Full Text Available Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability. The food that is a subject of the health claim, a combination of diosmin, troxerutin and hesperidin, is sufficiently characterised. The claimed effect, maintenance of normal venous-capillary permeability, is a beneficial physiological effect. No human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim were provided by the applicant. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of diosmin, troxerutin and hesperidin and the maintenance of normal venous-capillary permeability.

  20. Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-01-01

    Full Text Available Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone. The food that is a subject of the health claim, a combination of diosmin, troxerutin and hesperidin, is sufficiently characterised. The claimed effect, maintenance of normal venous tone, is a beneficial physiological effect. No human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim were provided by the applicant. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of diosmin, troxerutin and hesperidin and the maintenance of normal venous tone.

  1. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to sugar beet fibre and increasing faecal bulk pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    based on newly developed scientific evidence related to sugar beet fibre and “increasing faecal bulk”. The food constituent that is the subject of the health claim is sugar beet fibre. The Panel considers that sugar beet fibre is sufficiently characterised in relation to the claimed effect. The claimed......Following an application from Nordic Sugar A/S, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Denmark, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim...... that a cause and effect relationship has been established between the consumption of sugar beet fibre and increasing faecal bulk. The following wording reflects the scientific evidence: “Sugar beet fibre increases faecal bulk”. In order to bear the claim a food should be at least “high in fibre” as per...

  2. Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to sugar beet fibre and decreasing intestinal transit time pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nordic Sugar A/S, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Denmark, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim...... based on newly developed scientific evidence related to sugar beet fibre and “decreasing intestinal transit time”. The food constituent that is the subject of the health claim is sugar beet fibre. This opinion applies to sugar beet fibre naturally present in foods and to those forms added to foods...... that decreasing intestinal (orofaecal) transit time may be a beneficial physiological effect. The applicant provided four human studies as pertinent to the health claim. The Panel considers that no conclusion can be drawn from three studies for the scientific substantiation of the claim owing to methodological...

  3. EC motors for blowers; EC-Motoren fuer Luefter

    Energy Technology Data Exchange (ETDEWEB)

    Sauer, Thomas; Reiff, Ellen-Christine

    2009-10-15

    There are highly flexible commercial ventilation and air conditioning systems for server rooms which combine energy savings with optimum room air quality. EC blowers contribute to this and reduce also body sound. (orig./GL)

  4. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to L-tyrosine and contribution to normal synthesis of dopamine pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Vitabiotics Ltd. pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim......-tyrosine in the normal synthesis of catecholamines for the general population with a favourable outcome in a previous opinion under Article 13(1) of Regulation (EC) No 1924/2006. L-Tyrosine is the starting point for the synthesis of all catecholamines, including dopamine. The Panel concludes that a cause and effect....... The following wording reflects the scientific evidence: “L-tyrosine contributes to normal synthesis of dopamine”. In order to bear the claim a food should be at least a source of protein as per Annex to Regulation (EC) No 1924/2006. Such amounts can be easily consumed as part of a balanced diet. The target...

  5. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to L-ornithine and contribution to the regulation of the urea cycle (ID 4270) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of a health...... claim in relation to L-ornithine and contribution to the regulation of the urea cycle. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from...

  6. Scientific Opinion on the substantiation of a health claim related to Rosbacher drive® and increased attention pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-02-01

    Full Text Available Following an application from Hassia Mineralquellen GmbH & Co KG, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Germany, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Rosbacher drive® and increased attention. The Panel considers that Rosbacher drive®, which contains natural mineral water plus grape juice, lemon juice, pomegranate juice, elderberry juice, isomaltulose, sucrose, fructose syrup, caffeine, ascorbic acid and natural flavourings, is sufficiently characterised. The claimed effect, increased attention, is a beneficial physiological effect. The single study which was carried out with Rosbacher drive® was an open-label, non-randomised sequential study and the study did not report on any outcomes of attention. No conclusions can be drawn from this study for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of Rosbacher drive® and increased attention.

  7. Scientific Opinion on the substantiation of a health claim related to KF2BL20 and maintenance of normal hair pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to KF2BL20, which is a combination of keratin, copper, zinc, niacin, pantothenic acid, pyridoxine and D-biotin, and maintenance of normal hair. The Panel considers that KF2BL20 is sufficiently characterised. The claimed effect is “helps to reinforce hair strength and normal hair function and contributes to reduce hair loss”. The target population proposed by the applicant is healthy adults in the general population. The Panel considers that maintenance of normal hair is a beneficial physiological effect. The applicant identified one single arm study as being pertinent to the health claim. The Panel notes that this study was uncontrolled and considers that no conclusions can be drawn from this study for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of KF2BL20 and maintenance of normal hair.

  8. Scientific Opinion on the substantiation of a health claim related to beta-alanine and increase in physical performance during short-duration, high-intensity exercise pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-07-01

    Full Text Available Following an application from Natural Alternative International, Inc. (NAI, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to beta-alanine and increase in physical performance during short-duration, high-intensity exercise. The food constituent that is the subject of the claim is beta-alanine, which is sufficiently characterised. The Panel considers that an increase in physical performance during short-duration, high-intensity exercise is a beneficial physiological effect. In weighing the evidence the Panel took into account that only one out of 11 pertinent human intervention studies (including 14 pertinent outcomes from which conclusions could be drawn showed an effect of beta-alanine on physical performance during short-duration, high intensity exercise. The Panel concludes that a cause and effect relationship has not been established between the consumption of beta-alanine and an increase in physical performance during short-duration, high intensity exercise.

  9. Scientific Opinion on the substantiation of a health claim related to beta-palmitate and contribution to softening of stools pursuant to Article 14 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-02-01

    Full Text Available Following an application from Specialised Nutrition Europe (formerly IDACE, submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to beta-palmitate and contribution to softening of stools. The food constituent, beta-palmitate, that is the subject of the health claim, is sufficiently characterised. Contribution to softening of stools is a beneficial physiological effect for infants. In weighing the evidence the Panel took into account that, out of two human intervention studies with important methodological limitations, one suggested a stool-softening effect of beta-palmitate whereas the second did not, that one animal study did not support a stool-softening effect of beta-palmitate, and that the evidence provided for a mechanism by which beta-palmitate could contribute to the softening of stools is weak. The Panel concludes that a cause and effect relationship has not been established between the consumption of beta-palmitate and softening of stools.

  10. Scientific Opinion on the substantiation of a health claim related to “Femilub®” and maintenance of vaginal moisture pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-09-01

    Full Text Available

    Following an application from Nutrilinks Sarl submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to provide a scientific opinion on a health claim related to “Femilub®” and maintenance of vaginal moisture. The food that is the subject of the health claim, “Femilub®”, which is a combination of macadamia oil, borage oil, perilla oil, d‑α‑tocopherol and biotin, is sufficiently characterised. The claimed effect, maintenance of vaginal moisture, is a beneficial physiological effect. No human intervention studies were provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect relationship has not been established between the consumption of “Femilub®” and maintenance of vaginal moisture.

  11. Scientific Opinion on the substantiation of a health claim related to barley soup “Orzotto” and protection of blood lipids from oxidative damage pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-01-01

    Full Text Available Following an application from Italsur srl, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to barley soup “Orzotto” and protection of blood lipids from oxidative damage. The Panel considers that barley soup “Orzotto”, which is a vegetable mix containing pearled barley, Tuscan Black cabbage, potatoes, “blu savoy” cabbage, purple carrots, “bi coloured” spinach, “tri-coloured” Swiss chard, onions, red and yellow celery and parsley, is sufficiently characterised. The claimed effect, protection of blood lipids from oxidative damage, may be a beneficial physiological effect. No human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim were provided by the applicant. The Panel concludes that a cause and effect relationship has not been established between the consumption of barley soup “Orzotto” and protection of blood lipids from oxidative damage.

  12. Scientific Opinion on the substantiation of a health claim related to Slendesta® Potato Extract and reduction of body weight pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-02-01

    Full Text Available Following an application from Kemin Foods LC, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Slendesta® Potato Extract and reduction of body weight. The food constituent, Slendesta® Potato Extract, that is the subject of the health claim is sufficiently characterised. The claimed effect, a reduction of body weight, is a beneficial physiological effect for overweight individuals. In weighing the evidence, the Panel took into account that all four human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim did not show an effect of Slendesta® Potato Extract on the reduction of body weight. The Panel concludes that a cause and effect relationship has not been established between the consumption of Slendesta® Potato Extract and reduction of body weight.

  13. Scientific Opinion on the substantiation of a health claim related to Bimuno® GOS and reducing gastro-intestinal discomfort pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-06-01

    Full Text Available Following an application from Clasado Limited, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Malta, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Bimuno® GOS and reducing gastro-intestinal discomfort. The food constituent, Bimuno® GOS, a mixture of β-galacto-oligosaccharides, which is the subject of the health claim, is sufficiently characterised. The claimed effect proposed by the applicant is “reduce bloating, flatulence and abdominal pain. These effects can be described collectively as abdominal discomfort” and the target population proposed by the applicant is the general adult population. Reducing gastro-intestinal discomfort is a beneficial physiological effect. A health claim on Bimuno® GOS and reducing gastro-intestinal discomfort has already been assessed by the Panel with an unfavourable outcome. The supplementary information submitted by the applicant in this application did not provide evidence that could be used for the scientific substantiation of this claim.

  14. Scientific Opinion on the substantiation of a health claim related to Lactobacillus rhamnosus GG and maintenance of normal defecation during antibiotic treatment pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-06-01

    Full Text Available Following an application from Fuko Pharma Ltd, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Finland, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Lactobacillus rhamnosus GG and maintenance of normal defecation during antibiotic treatment. The food constituent, Lactobacillus rhamnosus GG, which is the subject of the health claim, is sufficiently characterised. The claimed effect proposed by the applicant is “help to maintain normal defecation during antibiotic treatment” and the target population proposed by the applicant is “healthy outpatient adults and children on oral antibiotic treatment”. Maintenance of normal defecation during antibiotic treatment is a beneficial physiological effect. The Panel notes that the information submitted from five out of seven human intervention studies is insufficient to allow a full scientific evaluation, and that these studies have important methodological limitations. No conclusions could be drawn from these studies for the scientific substantiation of the claim. The remaining two human intervention studies, from which conclusions could be drawn for the scientific substantiation of the claim, did not show an effect of Lactobacillus rhamnosus GG on the incidence of diarrhoea resulting from antibiotic treatment. The Panel concludes that a cause and effect relationship has not been established between the consumption of Lactobacillus rhamnosus GG and maintenance of normal defecation during antibiotic treatment.

  15. Scientific Opinion on the substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood concentrations of triglycerides pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood concentrations of triglycerides. The food that is the subject of the health claim, OptiEFAX™, which is standardised pure krill oil, is sufficiently characterised in relation to the claimed effect. The claimed effect, maintenance of normal blood concentrations of triglycerides, is a beneficial physiological effect. The target population proposed by the applicant is the general population. No human studies have been provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect relationship has not been established between the consumption of OptiEFAX™ and maintenance of normal blood concentrations of triglycerides.

  16. Scientific Opinion on the substantiation of a health claim related to krill oil and maintenance of joint comfort pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-12-01

    Full Text Available Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim related to krill oil and maintenance of joint comfort. The Panel considers that krill oil is sufficiently characterised. The claimed effect proposed by the applicant is “helps to improve the comfort of sensitive joints”. The Panel considers that maintenance of joint comfort is a beneficial physiological effect. The applicant identified one human intervention study as being pertinent to the health claim. The Panel notes that chronic inflammation was an inclusion criterion of the study, that a significant number of the patients recruited were reported to have confirmed diagnosis of osteoarthritis, rheumatoid arthritis, or of both cardiovascular disease and osteoarthritis, and that the WOMAC osteoarthritis questionnaire was administered only to patients with arthritic disease (osteoarthritis or rheumatoid arthritis. The Panel also notes that no evidence which could justify the extrapolation of the results, obtained in patients with joint diseases characterised by chronic inflammation, to the target population, subjects without chronic joint diseases, was provided by the applicant. The Panel considers that no conclusions can be drawn from this study for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of krill oil and maintenance of joint comfort.

  17. Scientific Opinion on the substantiation of a health claim related to cytidine 5-diphosphocholine and maintenance of normal vision pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-02-01

    Full Text Available Following an application from Omikron Italia S.r.l. submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to cytidine 5-diphosphocholine and maintenance of normal vision. The Panel considers that the food constituent cytidine 5-diphosphocholine (CDP-choline or citicoline, which is the subject of the health claim, is sufficiently characterised. The claimed effect, maintenance of normal vision, is a beneficial physiological effect. The Panel considers that no conclusions can be drawn from the three narrative reviews and the eight human intervention studies provided by the applicant for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of CDP-choline and maintenance of normal vision.

  18. 76 FR 39850 - The Manufacturing Council: Meeting

    Science.gov (United States)

    2011-07-07

    ... International Trade Administration The Manufacturing Council: Meeting AGENCY: International Trade Administration, U.S. Department of Commerce. ] ACTION: Notice of an open meeting. SUMMARY: The Manufacturing Council..., energy regulation reform, trade agreements and other issues affecting the U.S. manufacturing sector...

  19. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to cytidine 5 -diphosphocholine and maintenance of normal vision pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Omikron Italia S.r.l. submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion...

  20. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to Saccharomyces boulardii ATY-SB-101 (BCCM/MUCL 53837) (ID 1010, 1011, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on health claims pursuant to Article 13.1 of Regulation (EC) No 1924/2006 in the framework of further assessment related to Saccharomyces boulardii A...

  1. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to EffEXT™ and maintenance of normal joint mobility pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health cla...

  2. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014 . Scientific Opinion on the substantiation of a health claim related to zinc and normal function of the immune system pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...

  3. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014 . Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non-haem iron absorption pursuant to Article 14 of Regulation (EC ) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to ...

  4. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 20 13 . Scientific Opinion on the substantiatio n of a health claim related to iron and contribution to normal cognitive development pursuant to Article 14 of Regulation (EC ) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from IDACE, submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim relate...

  5. EFSA NDA Panel (EFSA Panel on Dietetic Product s, Nutrition and Allergies), 2013 . Scientific Opinion on the substantiation of a health claim related to vitamin A and contribution to normal development and function of the immune system pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from IDACE, submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim relate...

  6. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies) , 2014 . Scientific Opinion on the substantiation of a health claim related to Rosbacher drive® and increased attention pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Hassia Mineralquellen GmbH & Co KG, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver...

  7. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to a combination of lycopene, vitamin E, lutein and selenium and “ helps to prepare and activate tannin g ” pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Cyprus, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health clai...

  8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to Slendesta® Potato Extract and reduction of body weight pursuant to Article 13(5) of Regulation (EC) No 19 24/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Kemin Foods LC, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scient...

  9. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to a combination of lutein and zeaxanthin and improved vision under bright light conditions pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to a combination of lutein and zeaxanthin and improved vision under bright light conditions pursuant to Article 13(5) of Regulation (EC) No 1924/2006....

  10. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to Bifidobacterium animalis subsp. lactis LMG P-21384 and changes in bowel function (ID 2940, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to provide a scientific opinion on a health claim pursuant to Article 13 of Regulation (EC) No 1924/2006 in the framework of further assessment in relation to Bifidobacterium...

  11. EFSA NDA Panel (EFSA Panel on Dietetic Product s, Nutrition and Allergies), 2013 . Scientific Opinion on the substantiation of a health claim related to magnesium and contributio n to normal development of bone pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from IDACE, submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim relate...

  12. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to isolated soy protein and reduction of blood LDL-cholesterol concentrations pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from the European Natural Soyfood Manufacturers Association (ENSA), the European Vegetable Protein Federation (EUVEPRO) and the Soya Protein Association (SPA), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel...

  13. 小干扰RNA 抑制Pokemon表达对肺癌细胞A549和食管癌细胞EC109增殖的影响%Effects of Down-regulating Pokemon Expression by siRNA on Proliferation of Lung Cancer Cell A549 and Esophageal Cancer Cell EC109

    Institute of Scientific and Technical Information of China (English)

    沈惠琳; 叶月芳; 丛德刚

    2014-01-01

    目的:探讨Pokemon特异性小干扰RNA对肺癌细胞A549和食管癌细胞EC109 增殖的影响.方法:瞬时转染Pokemon特异性小干扰RNA至肺癌细胞A549和食管癌细胞EC109,RT-PCR、Western Blot技术检测转染后细胞中Pokemon的mRNA和蛋白表达水平,检测细胞的增殖及细胞周期变化.结果:与空白组和阴性对照组相比,瞬时转染Pokemon小干扰RNA后,肺癌细胞A549和食管癌细胞EC109中Pokemon的mRNA水平均下降至25%~35%,蛋白水平亦明显下降.细胞增殖能力在培养24,48,72 h均显著降低(P<0.05).细胞周期分析显示转染Pokemon小干扰RNA后S期的比例显著高于siRNA阴性对照组(A549细胞:55.7%±2.5% vs 42.7%±0.6%,P<0.01;EC109细胞:67.7%±2.5% vs 52.0%±2.0%,P<0.01).G1期的比例显著低于siRNA阴性对照组(A549细胞:33.0%±2.0% vs 45.3%±1.5%,P<0.01;EC109细胞:30.7%±1.2% vs 44.0%±1.7%,P<0.01).两种细胞均阻滞于S期.结论:Pokemon小干扰RNA可抑制肺癌细胞A549和食管癌细胞EC109 的增殖.

  14. Proposal for a decision of the EC Council concerning the planning of a sectoral R and D programme in the field of raw materials, 1982 to 1985. Vorschlag fuer einen Beschluss des Rates zur Festlegung eines sektoralen Forschungs- und Entwicklungsprogrammes auf dem Gebiet der Rohstoffe 1982 bis 1985

    Energy Technology Data Exchange (ETDEWEB)

    1981-01-01

    The subprogramme II of the research programme is concerned with the update of the first R + D programme in the field of uranium prospecting and mining which was accepted by the Council on 6th March 1978. This decision (78/246/EURATOM) was amended by the Council on 28th April 1981. The new decision schedules a five-year run for the first programme, expiring on 31st December 1982. The contents of the prolonged programme corresponds to the proposed subprogramme. The problem includes two research fields: research field I: uranium prospecting, res. field II: uranium mining and recovery. Document COM(80)382 endg. is a detailed description of subprogramme II. Additional means shall be required for prolonging the subprogramme beyond the year 1982.

  15. 24 CFR 964.117 - Resident council partnerships.

    Science.gov (United States)

    2010-04-01

    ... § 964.117 Resident council partnerships. A resident council may form partnerships with outside... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Resident council partnerships. 964.117 Section 964.117 Housing and Urban Development Regulations Relating to Housing and...

  16. Scientific Opinion on the substantiation of a health claim related to Wheat Polar Lipid Extract and protection of the skin against dehydration pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Extraction Purification Innovation France, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Wheat Polar Lipid Extract and protection of the skin against dehydration. The Panel considers that Wheat Polar Lipid Extract is sufficiently characterised. The claimed effect is “contributes to improve skin hydration”. The target population proposed by the applicant is healthy adults with skin dryness. The Panel considers that protection of the skin against dehydration is a beneficial physiological effect. The applicant identified one published and two unpublished human intervention studies as being pertinent to the health claim. The Panel considers that no conclusions can be drawn from one uncontrolled pilot study, nor from one study which was not carried out with the food which is the subject of the claim. In weighing the evidence, the Panel took into account that one human intervention study reported an effect of consumption of Wheat Polar Lipid Extract on transepidermal water loss and skin water-holding capacity, but that the outcome of the study lacked plausibility given the limitations in the study design, and that the evidence provided in support of a mechanism was weak. The Panel concludes that a cause and effect relationship has not been established between the consumption of Wheat Polar Lipid Extract and protection of the skin against dehydration.

  17. Scientific Opinion on the substantiation of a health claim related to EffEXT™ and maintenance of normal joint mobility pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-12-01

    Full Text Available Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to EffEXT™ and maintenance of normal joint mobility. The Panel considers that EffEXT™, which is standardised pure krill oil, is sufficiently characterised. The claimed effect proposed by the applicant is “contributes to support joint flexibility”. The Panel considers that maintenance of normal joint mobility is a beneficial physiological effect. The applicant identified one human intervention study as being pertinent to the health claim. The Panel notes that chronic inflammation was an inclusion criterion of the study, that a significant number of the patients recruited were reported to have confirmed diagnosis of osteoarthritis, rheumatoid arthritis, or of both cardiovascular disease and osteoarthritis, and that the WOMAC osteoarthritis questionnaire was administered only to patients with arthritic disease (osteoarthritis or rheumatoid arthritis. The Panel also notes that no evidence which could justify the extrapolation of the results, obtained in patients with joint diseases characterised by chronic inflammation, to the target population, subjects without chronic joint diseases, was provided by the applicant. The Panel considers that no conclusions can be drawn from this study for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of EffEXT™ and maintenance of normal joint mobility.

  18. Scientific Opinion on the substantiation of a health claim related to ?native chicory inulin? and maintenance of normal defecation by increasing stool frequency pursuant to Article 13.5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2015-01-01

    Full Text Available Following an application from BENEO-Orafti S.A., submitted pursuant to Article 13.5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to “native chicory inulin” and maintenance of normal defecation by increasing stool frequency. The food constituent that is a subject of a claim is “native chicory inulin”. The Panel considers that “native chicory inulin”, a non-fractionated mixture of monosaccharides (< 10%, disaccharides, inulin-type fructans and inulin extracted from chicory, with a mean DP ≥ 9, is sufficiently characterised in relation to the claimed effect. The Panel considers that maintenance of normal defecation by increasing stool frequency (provided that it does not result in diarrhoea is a beneficial physiological effect. Six studies involving 86 subjects consistently showed that consumption of “native chicory inulin” at an amount of at least 12 g/day increases stool frequency. The Panel also notes the plausible mechanisms by which inulin and inulin-type fructans in “native chicory inulin” could exert the claimed effect. The Panel concludes that a cause and effect relationship has been established between the consumption of “native chicory inulin” and maintenance of normal defecation by increasing stool frequency. The following wording reflects the scientific evidence: “Chicory inulin contributes to maintenance of normal defecation by increasing stool frequency”. In order to obtain the claimed effect, 12 g of “native chicory inulin” should be consumed daily.

  19. Scientific Opinion on the substantiation of a health claim related to a standardised aqueous extract from white kidney bean (Phaseolus vulgaris L. and reduction of body weight pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-07-01

    Full Text Available Following an application from InQpharm Europe Ltd, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of the United Kingdom, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a standardised aqueous extract from white kidney bean (Phaseolus vulgaris L. and reduction of body weight. The Panel considers that the food is sufficiently characterised. A reduction in body weight is a beneficial physiological effect for overweight individuals. The applicant identified a total of four human intervention studies which investigated the effects of the aqueous extract from white kidney bean on body weight as being pertinent to the claim. No conclusions could be drawn from two of these four studies. In weighing the evidence, the Panel took into account that one human intervention study showed an effect of the standardised aqueous extract from white kidney bean in reducing body weight when consumed for 12 weeks, that the reduction in body weight was mostly through a reduction in body fat and that the effect of the standardised aqueous extract from white kidney bean on body weight was supported by a second study of shorter duration. However, the Panel also took into account that the first study was at risk of bias, that the supportive study suffered from methodological limitations and that no evidence was provided for a mechanism by which the standardised aqueous extract from white kidney bean could exert the claimed effect. The Panel concludes that the evidence provided is insufficient to establish a cause and effect relationship between the consumption of the standardised aqueous extract from white kidney bean (Phaseolus vulgaris L. and reduction of body weight.

  20. APA Council Reports.

    Science.gov (United States)

    2017-10-01

    At the fall component meetings of the American Psychiatric Association in Arlington, Va., September 13-16, 2017, the APA councils heard reports from their components. Following are summaries of the activities of the councils and their components.

  1. APA Council Reports.

    Science.gov (United States)

    2016-10-01

    At the fall component meetings of the American Psychiatric Association in Crystal City, Va., September 14-17, 2016, the APA councils heard reports from their components. Following are summaries of the activities of the councils and their components.

  2. More efficient policy of energy and regional electricity supply by the directive 96/92/EC of the European Parliament and of the Council of 10 december 1996 concerning common rules for the internal market in electricity; Effizientere Energiepolitik und regionale Elektrizitaetsversorgung durch die EU-Elektrizitaetsrichtlinie 1996. Politikfeldanalyse der europaeischen, deutschen und bayerischen Energiepolitik und Elektrizitaetswirtschaft im Zusammenhang mit der Entstehung und Umsetzung der EU-Richtlinie 96 sowie der Veraenderung der Effizienz in der traditionellen Elektrizitaetsversorgung unter supranationalem EU-Einfluss

    Energy Technology Data Exchange (ETDEWEB)

    Furtner, Franz

    2006-07-01

    The German energy policy and its main addressees, the regional electricity companies (EVU), are going through a critical phase at the beginning of the 21st century. The increasing complexity and inconsistency of energy issues have, in Germany and in other countries, led to decisions which again have produced extensive, but not yet foreseeable developments, as, for example, the liberalisation of the electricity and gas market within the European Union. The first objective of this paper is an empirical analysis of the regional electricity supply industry in Germany and particularly in Bavaria in so far as it is relevant for energy politics, as well as an introduction to the German energy policy up to approximately the time when the Directive 96/92/EC of the European Parliament and the Council of 19 December 1996 concerning common rules for the internal market in electricity, was passed. Moreover, findings for the definition of energy efficiency in electricity supply and of the policy analysis are outlined. The second objective of this paper is the analysis and evaluation of the European Union energy policy, in particular of the Directive 96/92/EC, its formation and how it has been put into action by the German and Bavarian electricity supply industry. Energy efficiency of the electricity supply serves as a yardstick, the research method employed is the policy analysis. The main part of this paper, by comparing objectives to effects and by evaluating interviews with energy experts, examines the questions if, in what ways and to what extent the Directive 96/92/EC has led to an increase of energy efficiency in the narrow as well as in the boarder sense, within the EU, Germany and Bavaria. Additionally, three hypotheses are tested: firstly the significance of energy efficiency (in the narrow sense), secondly the alignment of European energy supply, and thirdly the importance of supranational control through EU politics. The results are presented in tabular form, and the

  3. 75 FR 80040 - Manufacturing Council

    Science.gov (United States)

    2010-12-21

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... Manufacturing Council. SUMMARY: On November 23, 2010, the Department of Commerce's International Trade... vacant position on the Manufacturing Council (Council). The November 23, 2010 notice provided that all...

  4. 75 FR 30781 - Manufacturing Council

    Science.gov (United States)

    2010-06-02

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... Manufacturing Council. SUMMARY: On March 16, 2010, the Department of Commerce's International Trade... the Manufacturing Council (Council). The March 16, 2010 notice provided that all applications must be...

  5. Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Barry Callebaut Belgium nv, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation. Cocoa flavanols are sufficiently characterised. The claimed effect is “help maintain endothelium-dependent vasodilation which contributes to healthy blood flow”. The target population proposed by the applicant is the general healthy adult population. The Panel considers that maintenance of normal endothelium-dependent vasodilation is a beneficial physiological effect. In weighing the evidence, the Panel took into account that cocoa flavanols consumed for 12 weeks have been shown to increase fasting ED-FMD significantly in the target population in one human intervention study, that in another study the effect was dose-dependent and occurred after one week of consumption, that the effect was supported by two additional studies, and that it was also observed in two out of three studies in patients under pharmacological treatment for coronary artery disease, although the mechanisms by which regular consumption of cocoa flavanols may induce a sustained effect on fasting ED-FMD are unknown. The Panel concludes that a cause and effect relationship has been established between the consumption of cocoa flavanols and maintenance of normal endothelium-dependent vasodilation. The following wording reflects the scientific evidence: “Cocoa flavanols help maintain endothelium-dependent vasodilation, which contributes to normal blood flow”. In order to obtain the claimed effect, 200 mg of cocoa flavanols should be consumed daily. This amount could be provided by 2.5 g of high-flavanol cocoa powder or 10 g of high-flavanol dark chocolate, both of which can be

  6. Scientific Opinion on the substantiation of a health claim related to non digestible carbohydrates and a reduction of post prandial glycaemic responses pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-01-01

    Full Text Available Following an application from Beneo-Orafti SA, Sensus BV and Cosucra-Groupe Warcoing SA, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to fructo-oligosaccharides (FOS from inulin and a reduction of post-prandial glycaemic responses. Non-digestible carbohydrates including FOS are resistant to hydrolysis and absorption in the small intestine and do not contribute to post-prandial glycaemia. This opinion applies to non-digestible carbohydrates (e.g. non-starch polysaccharides, resistant oligosaccharides and resistant starch which should replace sugars in foods or beverages in order to obtain the claimed effect. The Panel considers that the food constituent, non-digestible carbohydrates, which is the subject of the health claim, and the food constituent (i.e. sugars that non-digestible carbohydrates should replace in foods or beverages, are both sufficiently characterised in relation to the claimed effect. The Panel considers that a reduction of post-prandial glycaemic responses might be a beneficial physiological effect. In weighing the evidence, the Panel took into account that consumption of non-digestible carbohydrates results in reduced post-prandial blood glucose (and insulinaemic responses compared with the consumption of sugars on a weight-by-weight basis owing to the non-digestibility in the small intestine and to a decrease in the amount of available carbohydrates, and that the consumption of foods/drinks in which non-digestible carbohydrates replaced sugars induced lower post-prandial glycaemic and insulinaemic responses than sugar-containing foods/drinks. The Panel concludes that a cause and effect relationship has been established between the consumption of foods/beverages containing non

  7. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to choline and “development of brain” pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked...... population is infants and young children from birth to three years of age. Taking into account that no evidence was provided for an effect of dietary choline deficiency in the normal development of the brain in infants and young children, the Panel considers that the claimed effect, “development of brain......” for infants and young children from birth to three years in relation to dietary choline, is not sufficiently defined for a scientific evaluation. The Panel considers that the claimed effect is general and non-specific, and does not refer to any specific health claim as required by Regulation (EC) No 1924/2006....

  8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to alpha-cyclodextrin and reduction of post-prandial glycaemic responses (ID 2926, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a health claim pursuant to Article 13.1 of Regulation (EC) No 1924/2006 in the framework of further assessment related to alpha-cyclodextrin and r......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a health claim pursuant to Article 13.1 of Regulation (EC) No 1924/2006 in the framework of further assessment related to alpha......), may be a beneficial physiological effect. The proposed target population is individuals who wish to reduce their post-prandial glycaemic responses. In weighing the evidence, the Panel took into account that two intervention studies showed a significant effect of alpha-cyclodextrin added to starch...

  9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to lutein and maintenance of normal vision (ID 1603, 1604, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006 in the framework of further assessment related to lutein and mainte......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006 in the framework of further assessment related to lutein...... into account that one human intervention study in healthy subjects did not show an effect of lutein on visual acuity or glare sensitivity, that the results of this study were inconsistent as regards contrast sensitivity, and that the evidence provided for a mechanism by which lutein could exert the claimed...

  10. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    OpenAIRE

    Tetens, Inge

    2012-01-01

    Following an application from Barry Callebaut Belgium nv, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation. Cocoa flavanols are sufficiently characterised. The claimed effect is “help maintain endothelium-...

  11. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to medium-chain triglycerides and reduction in body weight (ID 643, 677, 1614) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    OpenAIRE

    Tetens, Inge

    2011-01-01

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health claims in relation to medium-chain triglycerides and reduction in body weight. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article ...

  12. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    OpenAIRE

    Tetens, Inge

    2012-01-01

    Following an application from Barry Callebaut Belgium nv, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation. Cocoa flavanols are sufficiently characterised. The claimed effect is “help maintain endothelium-...

  13. 48 CFR 1.201-1 - The two councils.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false The two councils. 1.201-1... ACQUISITION REGULATIONS SYSTEM Administration 1.201-1 The two councils. (a) Subject to the authorities discussed in 1.103, revisions to the FAR will be prepared and issued through the coordinated action of two...

  14. 77 FR 2275 - Manufacturing Council

    Science.gov (United States)

    2012-01-17

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an opportunity to apply for membership on the Manufacturing Council... Manufacturing Council (Council). The purpose of the Council is to advise the Secretary of Commerce on matters...

  15. 77 FR 56811 - Manufacturing Council

    Science.gov (United States)

    2012-09-14

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an Opportunity to Apply for Membership on the Manufacturing Council... ] Manufacturing Council (Council) for a two-year term to begin in fall 2012. The purpose of the Council is to...

  16. 76 FR 33244 - Manufacturing Council

    Science.gov (United States)

    2011-06-08

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an Opportunity To Apply for Membership on the Manufacturing Council... Manufacturing Council (Council). The purpose of the Council is to advise the Secretary of Commerce on matters...

  17. European works councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne

    2003-01-01

    The theme adressed by this paper is the opportunities for European Works Councils (EWCs) of gaining influence on corporate decisions in multinational companies.......The theme adressed by this paper is the opportunities for European Works Councils (EWCs) of gaining influence on corporate decisions in multinational companies....

  18. CLAFA Council Meeting Held

    Institute of Scientific and Technical Information of China (English)

    JiWei

    2004-01-01

    The Council Meeting of the China-Latin America Friendship Association (CLAFA) was held in Beijing on February 3, 2004. More than 30 council members attended the meeting. It was presided over by CLAFA Vice President Li Xiaolin. Cheng Siwei, CLAFA president and vice chairman of

  19. European works councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne

    2004-01-01

    The theme addressed by this artcle is the opportunities for European Works Councils of gaining influence on corporate decisions in multinational companies.......The theme addressed by this artcle is the opportunities for European Works Councils of gaining influence on corporate decisions in multinational companies....

  20. European works councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne

    2003-01-01

    The theme adressed by this paper is the opportunities for European Works Councils (EWCs) of gaining influence on corporate decisions in multinational companies.......The theme adressed by this paper is the opportunities for European Works Councils (EWCs) of gaining influence on corporate decisions in multinational companies....

  1. European works councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne

    2004-01-01

    The theme addressed by this artcle is the opportunities for European Works Councils of gaining influence on corporate decisions in multinational companies.......The theme addressed by this artcle is the opportunities for European Works Councils of gaining influence on corporate decisions in multinational companies....

  2. The Iraqi Governing Council

    Science.gov (United States)

    Social Education, 2004

    2004-01-01

    This article provides the details of the chronological events surrounding the establishment of a Governing Council in Iraq in July 2003 by the United States, acting as the leader of the Coalition Provisional Authority (CPA) that administers Iraq. The following topics are discussed in the article: (1) The Composition of the Governing Council; (2)…

  3. [Ethical aspects of human embryonic stem cell use and commercial umbilical cord blood stem cell banking. Ethical reflections on the occasion of the regulation of the European Council and Parliament on advanced therapy medicinal products].

    Science.gov (United States)

    Virt, G

    2010-01-01

    The regulation of the European Council and Parliament on advanced therapy medicinal products also includes therapies with human embryonic stem cells. The use of these stem cells is controversially and heavily discussed. Contrary to the use of adult stem cells, medical and ethical problems concerning the use of human embryonic stem cells persists, because this use is based on the destruction of human life at the very beginning. The regulation foresees, therefore, subsidiarity within the European Member States. Although there are no ethical problems in principle with the use of stem cells from the umbilical cord blood, there are social ethical doubts with the banking of these stem cells for autologous use without any currently foreseeable medical advantage by commercial blood banks. Also in this case subsidiarity is valid.

  4. Elections to Staff Council

    CERN Multimedia

    Saff Association

    2013-01-01

    2013 Elections to Staff Council   Vote! Make your voice heard and be many to elect the new Staff Council. More details on the elections can be found on the Staff Association web site (https://ap-vote.web.cern.ch/elections-2013).   Timetable elections Monday 28 October to Monday 11 November, 12:00 am voting Monday 18 and Monday 25 November, publication of the results in Echo Tuesday 19 November, Staff Association Assizes Tuesday 3 December, first meeting of the new Staff Council and election of the new Executive Committee The voting procedure is monitored by the Election Committee.

  5. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to diacylglycerol (DAG) oil and reduction of body weight pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claim related to diacylglycerol oil and reduction of body weight. The food constituent, diacylglycerol (DAG) oil, and the food constituents, vegetable oils of similar fatty acid composition containing mostly (>90%) triacylglycerol (TAG), which DAG oil should replace in order to obtain the claimed effect......Following an application from Kao Corporation, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health...

  6. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to foods with reduced amounts of sodium and maintenance of normal blood pressure (ID 336, 705, 1148, 1178, 1185, 1420) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health cla...... or directly from stakeholders. The food constituents that are the subjects of the health claims are “sodium/salt”, “low sodium/salt and/or increased potassium”, “food reduced/low in/free of sodium/salt and/or increased potassium”, “breads with salt content of...

  7. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Barry Callebaut Belgium nv, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation...... daily. This amount could be provided by 2.5 g of high-flavanol cocoa powder or 10 g of high-flavanol dark chocolate, both of which can be consumed in the context of a balanced diet. The target population is the general population....

  8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to Lactobacillus casei DG CNCM I-1572 and decreasing potentially pathogenic gastro-intestinal microorganisms (ID 2949, 3061, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006 in the framework of further assessment related to Lactobacillus cas...... DG CNCM I-1572 and decreasing potentially pathogenic gastro-intestinal microorganisms. The food constituent that is the subject of the health claim, Lactobacillus casei DG CNCM I-1572, is sufficiently characterised. The claimed effect, decreasing potentially pathogenic gastro...

  9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to sodium alginate and reduction of post-prandial glycaemic responses (ID 1868, 1881) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to sodium alginate and reduction of post-prandial glycaemic responses. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from...

  10. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to anthocyanins from Ribes nigrum L. and improvement of visual adaptation to the dark (ID 2750) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to anthocyanins from Ribes nigrum L. and improvement of visual adaptation to the dark. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States...

  11. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to glycaemic carbohydrates and maintenance of normal brain function (ID 603, 653) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to glycaemic carbohydrates and maintenance of normal brain function. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from...

  12. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to olive leaf (Olea europaea L.) water extract and increase in glucose tolerance pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Comvita New Zealand Limited, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... water extract for 12 weeks under the conditions of use proposed by the applicant. However, the results have not been replicated in other studies, and no evidence has been provided in relation to the mechanism by which the olive leaf water extract could exert the claimed effect. The scientific evidence...

  13. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to spermidine and prolongation of the growing phase (anagen) of the hair cycle pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Giuliani S.p.A., submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim related......, and that it could be considered to affect the general population. From the evidence provided by the applicant the Panel considers that the claimed effect is related to the treatment of pathological conditions leading to shortening of the anagen phase of hair growth. The Panel concludes that the claimed effect...

  14. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to glucose and contribution to energy-yielding metabolism pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claim related to glucose and “contributes to normal energy-yielding metabolism”. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food constituent that is the subject of the health claim is glucose, which is sufficiently......Following an application from Dextro Energy GmbH & Co. KG, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health...

  15. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to KF2BL20 and maintenance of normal hair pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    OpenAIRE

    Tetens, Inge

    2012-01-01

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to KF2BL20, which is a combination of keratin, copper, zinc, niacin, pantothenic acid, pyridoxine and D-biotin, and maintenance of normal hair. The Panel considers that KF2BL20 is sufficien...

  16. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to beta-palmitate and contribution to softening of stools pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked...... physiological effect for infants. In weighing the evidence the Panel took into account that, out of two human intervention studies with important methodological limitations, one suggested a stool-softening effect of beta-palmitate whereas the second did not, that one animal study did not support a stool...

  17. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to iodine and contribution to normal cognitive development pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... established role of iodine in preventing iodine deficiency disorders such as retarded mental and physical development in children and adolescents, and impaired mental function and reduced cognitive capacity for people of all ages. The Panel concludes that a cause and effect relationship has been established...

  18. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to Wheat Polar Lipid Extract and protection of the skin against dehydration pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Extraction Purification Innovation France, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... on transepidermal water loss and skin water-holding capacity, but that the outcome of the study lacked plausibility given the limitations in the study design, and that the evidence provided in support of a mechanism was weak. The Panel concludes that a cause and effect relationship has not been established between...

  19. EFSA Panel on Di etetic Products, Nutrition and Allergie s (NDA); Scientific Opinion on the substantiation of a health claim relate d to OXY 280 and reduction of body weight pur suant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Actina, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related...... relative to the placebo, and that no conclusions can be drawn from this study for the scientific substantiation of the claim. The Panel notes that no studies from which conclusions could be drawn for the scientific substantiation of the claim were provided by the applicant. The Panel concludes that a cause...

  20. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to Cynatine ® and maintenance of normal joint mobility pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Roxlor Nutra LLC, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health...... for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of Cynatine® and maintenance of normal joint mobility. © European Food Safety Authority, 2012...

  1. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood LDL-cholesterol concentrations pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nutrilinks Sarl, submitted for authorisation of a claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... of normal blood LDL-cholesterol concentrations, is a beneficial physiological effect. The target population proposed by the applicant is the general population. No human studies have been provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect...

  2. High-Statistics β+ / EC -Decay Study of 122Xe

    Science.gov (United States)

    Jigmeddorj, Badamsambuu; S1292 Collaboration

    2016-09-01

    The Xe isotopes are centrally located in the Z > 50 , N vibrational structure influenced by proton subshell gaps, perhaps leading to shape-coexistence that could give rise to strong E 0 transitions. Recent work on 124Xe has established nearly identical quadrupole collectivity for the pairing vibrational 03+ band and the ground state band. However, in 122Xe, the 03+ state has not been firmly identified. A high-statistics 122Cs β+ / EC decay experiment to obtain detailed spectroscopic data for low-spin states was performed at the TRIUMF-ISAC facility using the 8 π γ-ray spectrometer and its auxiliary detectors including PACES, an array of five Si(Li) detectors, for conversion electron spectroscopy. The decay scheme has been considerably extended through a γ- γ coincidence analysis, and 0+ states have been identified via γ- γ angular correlations. This work supported by the Natural Sciences and Engineering Research Council of Canada and the National Research Council of Canada.

  3. Medicare Appeals Council Decisions

    Data.gov (United States)

    U.S. Department of Health & Human Services — Decisions of the Departmental Appeals Board's Medicare Appeals Council involving claims for entitlement to Medicare and individual claims for Medicare coverage and...

  4. Medicare Appeals Council Decisions

    Data.gov (United States)

    U.S. Department of Health & Human Services — Decisions of the Departmental Appeals Board's Medicare Appeals Council involving claims for entitlement to Medicare and individual claims for Medicare coverage and...

  5. Allegheny County Council Districts

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset portrays the boundaries of the County Council Districts in Allegheny County. The dataset is based on municipal boundaries and City of Pittsburgh ward...

  6. Allegheny County Council Districts

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset portrays the boundaries of the County Council Districts in Allegheny County. The dataset is based on municipal boundaries and City of Pittsburgh ward...

  7. News from Council

    CERN Multimedia

    2015-01-01

    Today concludes a very busy week for Council. As you’ll have seen from the press release this morning, Council elected a new President, who will take up his mandate on 1 January along with the new management team, which was also approved by Council yesterday.   You’ll find full details of the incoming Director-General’s management team and structures here. Completing the configuration for the immediate future, Council also approved the medium term plan, along with the budget for 2016. In other Council business, two complete applications for Associate Membership were discussed. Following an earlier letter, India’s complete application was received and considered by Council. Consequently, a fact-finding mission has been established to report back before the end of the year. A new application was also received from Azerbaijan, with a fact-finding mission to be established. India’s involvement with CERN goes back to the 1970s, and the country...

  8. 77 FR 69794 - Manufacturing Council

    Science.gov (United States)

    2012-11-21

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... Manufacturing Council. SUMMARY: On September 14, 2012, the Department of Commerce's International Trade... appointment of 25 members of the Manufacturing Council (Council) for a two-year term to begin in fall 2012...

  9. 78 FR 67117 - Manufacturing Council

    Science.gov (United States)

    2013-11-08

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an Opportunity to Apply for Membership on the Manufacturing Council.... manufacturing industry to fill five vacant positions on the Manufacturing Council (Council). The purpose of the...

  10. 77 FR 66179 - Manufacturing Council

    Science.gov (United States)

    2012-11-02

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... manufacturing council. SUMMARY: On September 14, 2012, the Department of Commerce's International Trade... of 25 members of the Manufacturing Council (Council) for a two-year term to begin in fall 2012. The...

  11. The EC in the WTO: The three-level game of decision-making. What multilateralism can learn from regionalism

    Directory of Open Access Journals (Sweden)

    Rafael Leal-Arcas

    2004-09-01

    Full Text Available This paper is a comparative institutional analysis of the EC's decision-making process in trade policy by focusing on three variables, i.e., competence (whether national or EC competence in EC trade policy, control (who controls the EC's position in international trade negotiations: the Commission or the EU Member States? and efficiency versus accountability (technocratic versus democratic trade policy at the national and supranational levels. The empirical background is the World Trade Organization, to which the EC and its Member States are members and, more precisely, the Doha Development Agenda, where the position of the EC is analyzed. The EC institutions and their interaction with EU Member States' institutions and trade policy is the core of this paper. The problems that the enlarged EU will face in its internal decision-making process (such as transparency, efficiency, accountability can be paralleled to the WTO's decision-making process, and thus the European experience can be used as a role or guidance in the WTO forum so that we can learn from the EC's benefits and, more importantly, avoid the mistakes of the European experience in the decision-making process of international trade fora . The paper concludes that EC trade policy, as well as WTO rules and policies, need to change to become more efficient and accountable at the same time as they address the issue of lack of transparency and legitimacy of the current system of governance, denounced by the Laeken European Council. Thus, more leadership is needed.

  12. 7 CFR 1260.315 - Qualified State Beef Councils.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Qualified State Beef Councils. 1260.315 Section 1260... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BEEF PROMOTION AND RESEARCH Rules and Regulations § 1260.315 Qualified State Beef Councils. The following...

  13. Multiresidue determination of fluoroquinolones in poultry muscle and kidney according to the regulation 2002/657/EC. A systematic comparison of two different approaches: Liquid chromatography coupled to high-resolution mass spectrometry or tandem mass spectrometry.

    Science.gov (United States)

    Rocha, Diego G; Santos, Flavio A; da Silva, Júlio César C; Augusti, Rodinei; Faria, Adriana F

    2015-01-30

    This work involved the optimization and validation of two methods according to the Commission Decision 2002/657/EC directives for determining fluoroquinolones residues in samples of poultry muscle and kidney: ciprofloxacin, danofloxacin, difloxacin, enrofloxacin, flumequine, marbofloxacin, nalidixic acid, norfloxacin, ofloxacin, oxolinic acid, pipemidic acid and sarafloxacin. The extraction procedure was based on a QuEChERS approach, whose optimization employed a Box-Behnken 3(3) factorial design. A liquid chromatography-tandem mass spectrometry method (LC-MS/MS) was developed for determining the twelve analytes using the multiple reaction monitoring mode (MRM). Accuracy, evaluated by recovery studies, varied from 88.8 to 112.2% for the selected levels with RSD values lower than 12.3%. The second validated method employed high resolution mass spectrometry (HRMS) performed in the single ion monitoring mode (SIM), determining nine among twelve analytes. The validation parameters were evaluated as satisfactory, with recoveries from 82.5 to 114.4% and RSD lower than 8.7%. Decision limits and detection capabilities for both methods were reported. The two methods were statistically compared using the Student's t test, at 95% confidence level, resulting in no significant difference.

  14. Scientific Opinion on the substantiation of a health claim related to Vitis vinifera L. seeds extract and “helps to decrease swollen legs” pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-12-01

    Full Text Available Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Vitis vinifera L. seeds extract and “helps to decrease swollen legs”. The Panel considers that the food constituent which is the subject of the health claim is sufficiently characterised. Upon EFSA’s request for clarification, the applicant stated that the claimed effect was “helps to decrease swollen legs”, and that the beneficial physiological effect could be related to “helps to refine legs”. In the context of the references provided for the scientific substantiation of the claim, and in particular of the human intervention study which was conducted with the food constituent that is the subject of the health claim, the Panel notes that the claim refers to the reduction of peripheral oedema in the context of chronic clinical conditions (e.g. chronic venous insufficiency where the reduction of peripheral oedema is a therapeutic target for the treatment of the condition. The Panel considers that the reduction of peripheral oedema in the context of chronic clinical conditions is a therapeutic target for the treatment of the condition and does not comply with the criteria laid down in Regulation (EC No 1924/2006.

  15. Scientific Opinion on the substantiation of a health claim related to EffEXT™ and “helps to support joint function by maintaining low levels of plasma C-reactive protein” pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-09-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to EffEXT™ and “helps to support joint function by maintaining low levels of plasma C‑reactive protein”. The Panel considers that EffEXT™, which is standardised pure krill oil, is sufficiently characterised. The claimed effect is “helps to support joint function by maintaining low levels of plasma C-reactive protein”. The Panel notes that the claim refers to a reduction of inflammation indicated by a lowered concentration of plasma C-reactive protein. Whether or not reduction of inflammatory markers is considered beneficial depends on the context in which a claim is made. In the context of the study provided, the Panel notes that the claim refers to diseases such as osteoarthritis or rheumatoid arthritis, in which a reduction of inflammation would be a therapeutic target for the treatment of the disease. The Panel considers that the reduction of inflammation in the context of diseases such as osteoarthritis or rheumatoid arthritis is a therapeutic target for the treatment of the disease and does not comply with the criteria laid down in Regulation (EC No 1924/2006.

  16. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2015. Scientific Opinion on the substantiation of a health claim related to a combination of pomegranate pomace extract and greater galangal rhizome powder and an increase in the number of motile spermatozoa in semen, pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nerthus ApS, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Denmark, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scie......Following an application from Nerthus ApS, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Denmark, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion...... on the scientific substantiation of a health claim related to a combination of pomegranate pomace extract (standardised by its content of punicalagins) and greater galangal rhizome powder (standardised by its content of acetoxychavicol acetate) and an increase in the number of motile spermatozoa in semen. The Panel...... the combination of pomegranate pomace extract and greater galangal rhizome powder was consumed for three months, that no other human studies in which these results have been replicated were provided, and that no evidence was provided for a mechanism by which the food could exert the claimed effect. The Panel...

  17. A report from Council

    CERN Multimedia

    2014-01-01

    The June meeting of Council is always a very busy one, having approval of the next year’s budget and the MTP as fixed agenda points. This year in addition, we had discussions on enlargement, as well as on the pension fund. I’d like to use this message to bring you up to date on all of those matters.   I’ll begin with the good news that the 2015 budget and MTP were recommended for approval by Finance Committee on Wednesday, and approved by Council on Thursday. This is extremely good news, and a solid vote of confidence from Council in the current economic situation. Coupled with that, I am pleased to report that at the half way stage of 2014, some 89% of budget contributions for the year have been received. Turning now to enlargement, I can inform you that the task force that went to Pakistan came back with a positive report, and as a consequence Council has authorised us to finalise discussion with Pakistan for Associate Membership. Council also authoris...

  18. Special Issue: Selected papers from ECS'97

    DEFF Research Database (Denmark)

    1999-01-01

    This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia.......This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia....

  19. The EC-ASEAN COGEN programme

    Energy Technology Data Exchange (ETDEWEB)

    Pennington, M.; Lacrosse, L. [Asian Institute of Technology (Thailand); Schenkel, Y. [Centre de Recherches Agronomiques (Belgium)

    1996-12-31

    The EC-ASEAN COGEN Programme is a co-operation programme between the European Commission (EC) and the Association of South East Asian Nations (ASEAN) co-ordinated by the Asian Institute of Technology (AIT), Bangkok, Thailand. Its aim is to accelerate the implementation of proven technologies generating heat and/or power from wood and agroindustrial residues through partnerships between European and ASEAN companies. (orig.)

  20. Special Issue: Selected papers from ECS'97

    DEFF Research Database (Denmark)

    1999-01-01

    This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia.......This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia....

  1. 36 CFR 271.8 - Consultation with Association of State Foresters and the Advertising Council.

    Science.gov (United States)

    2010-07-01

    ... of State Foresters and the Advertising Council. 271.8 Section 271.8 Parks, Forests, and Public... Association of State Foresters and the Advertising Council. These regulations in this part have been issued after consultation with the Association of State Foresters and the Advertising Council....

  2. European Honors Council

    NARCIS (Netherlands)

    Dr. Marca Wolfensberger

    2016-01-01

    In M. Wolfensberger (Chair), Models of support. Break out session conducted at the Utrecht Honours Conference 2016: Honours Futures, June 2-3 Utrecht. The European Honors Council (EHC) is a new European network around the subject of talent development in European higher education.

  3. Elections to Staff Council

    CERN Multimedia

    Association du personnel

    2006-01-01

    The Staff Association will shortly be renewing the mandate of half of the Staff Council. This is an opportunity for you to become more directly involved in the Staff Association's work and help promote and defend the staff's interests and, more broadly, those of the Organization itself.

  4. Elections to Staff Council

    CERN Multimedia

    Association du personnel

    2007-01-01

    The Staff Association will shortly be renewing the mandate of half of the Staff Council. This is an opportunity for you to become more directly involved in the Staff Association’s work and help promote and defend the staff’s interests and, more broadly, those of the Organization itself.

  5. Australian Research Council

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Introduction The Australian Research Council(ARC) is the Australian Government's main agency for allocating research funding to academics and researchers in Australian universities.Its mission is to deliver policy and programs that advance Australian research and innovation globally and benefit the community.

  6. Elections to Staff Council

    CERN Multimedia

    Association du personnel

    2006-01-01

    The Staff Association will shortly be renewing the mandate of half of the Staff Council. This is an opportunity for you to become more directly involved in the Staff Association's work and help promote and defend the staff's interests and, more broadly, those of the Organization itself.

  7. Report from Council

    CERN Multimedia

    2015-01-01

    This week’s Council meeting was dominated by discussions about the long-term, sustainable future of CERN. Key points are progress on the Medium-Term Plan, the successful LHC restart, and enlargement.   The budget proposed by management for 2016 was well received, as were the measures to mitigate against the recent change in exchange rates. These items will be put to the vote in September. Discussions on CERN staff employment conditions were conducted in a constructive atmosphere this week, and will continue in future Council meetings. The Council also clearly voiced its congratulations for the smooth and successful start of LHC run 2, coming on top of a clear run of spectacular scientific and technological successes over recent years. In the current climate of austerity, these developments are a strong endorsement from the Council. Nevertheless, it would be disingenuous of me to pretend that everything is rosy. There has been an air of unease at CERN over recent months, which was v...

  8. Distance Education Council.

    Science.gov (United States)

    Indira Gandhi National Open University, New Delhi (India). Distance Education Council.

    Since its inception in India in 1962, distance education has grown in popularity. The Distance Education Council (DEC) directs distance learning within India's higher education system. The DEC's promotion, coordination, and maintenance of standards for distance education are its three major roles. Its initiatives include grants, support for…

  9. Elections to Staff Council

    CERN Multimedia

    Staff Association

    2011-01-01

    Elections to fill all seats in the Staff Council are being organized this month. The voting takes place from the 31st of October to the 14th of November, at noon. As you may have noted when reading Echo, many issues concerning our employment conditions are on the agenda of the coming months and will keep the next Staff Council very busy. So, make your voice heard and take part in the elections for a new Staff Council. By doing so, you will be encouraging the men and women who will be representing you over the next two years and they will doubtless appreciate your gratitude. Every member of the Staff Association will have received an email containing a link to the webpage which will allow voting. If you are a member of the Staff Association and you did not receive such an email, please contact the Staff Association secretariat (staff.association@cern.ch). Do not forget to vote * * * * * * * Vote Make your voice heard and be many to elect the new Staff Council. More details on the election...

  10. The climate policy of the EC - too hot to handle

    Energy Technology Data Exchange (ETDEWEB)

    Skjaerseth, J.B.

    1993-01-01

    Has the climate policy of the European Community (EC) become stronger According to our criteria for strength, it has not. First, even with perfect and timely implementation of the climate package, there is no guarantee that the Community will succeed in curbing the anticipated growth of future CO[sub 2] emissions by the year 2000, to at least 12% of 1990 levels. Part of the decrease is expected from quite uncertain ''educative effects'', while 1.5% is left to ''new activities foreseen''. In addition, the expanding transport sector, which formed a central part of earlier proposals, has to a large extent been left out of the Community's climate policy. The stabilization target was adopted in October 1990; in 1991, CO[sub 2] emissions increased by about 4% in the Community. Secondly, the adoption and implementation of the climate package is uncertain. No legal proposals presented in the spring of 1992 have yet been adopted by the Council. Moreover, the proposed energy/carbon tax, which is to account for half of expected reductions, will not be implemented until other OECD countries follow suit. Thirdly, despite the clear political signals of the Community stabilization objective, almost half the member countries have no national goal and only three have a national policy on how to achieve their goals. Thus, from the remarkably smooth process up to goal formulation, the Community's climate policy seems to have been substantially watered down. On the other hand, the climate policy of the EC currently exists as a political commitment, and is thus quite sensitive to general political developments and fluctuations both within the Community and outside. 129 refs., 9 tabs.

  11. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to folate and maintenance of normal blood pressure (ID 176) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to folate and maintenance of normal blood pressure. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders...... and supplements) were collected by semi-quantitative food frequency questionnaires. On the basis of the data presented, the Panel concludes that a cause and effects relationship has not been established between the dietary intake of folate and maintenance of normal blood pressure....

  12. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) and contribution to normal cognitive function (ID 532) and maintenance, of normal bone (ID 642, 697, 1552) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food constituents that are the subjects of the health claims are “omega-3 and omega-6 fatty acids (GLA)”, “gamma-linolenic acid + eicosapentaenoic acid (GLA+EPA)”, and “evening primrose oil...... and fish oil”. From the references provided, the Panel assumes that the food constituents that are the subject of the claims are the n-6 fatty acid gamma-linolenic acid (GLA) in evening primrose oil and the n-3 long-chain polyunsaturated fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...

  13. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to Bimuno® GOS and reducing gastro-intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Clasado Ltd., submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health...... identified eight human intervention studies, two human observational studies, and three non-human studies as being pertinent to the health claim. The Panel considers that owing to important methodological limitations, no conclusions with respect to the scientific substantiation of the claim can be drawn from...... the two human intervention studies which investigated the effect of Bimuno® GOS on symptoms related to gastro-intestinal discomfort. The remaining human studies, and the animal and in vitro studies, addressed the effects of either Bimuno® GOS or other galacto-oligosaccharides from a variety of sources...

  14. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to coffee C21 and reduction of spontaneous DNA strand breaks pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    additional human studies investigated coffees other than coffee C21. Two of these had no control group and a third study did not assess spontaneous DNA strand breaks. No conclusions could be drawn from these human studies for the scientific substantiation of the claim. The fourth study did not show an effect......Following an application from Tchibo GmbH, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim related...... to coffee C21 and reduction of spontaneous DNA strand breaks. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food constituent that is the subject of the health claim is coffee C21, which is sufficiently characterised. The claimed...

  15. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to “slowly digestible starch in starch-containing foods” and “reduction of postprandial glycaemic responses” pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Kraft Foods Europe, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health...... claim related to “slowly digestible starch in starch-containing foods” and “reduction of post-prandial glycaemic responses”. The food constituent, “slowly digestible starch (SDS)”, as defined by the applicant in applying an appropriate method (such as the method developed by Englyst et al. (1996; 1999......)), which is the subject of the health claim, and the comparator food constituent, “rapidly digestible starch (RDS)”, as defined by the applicant, are sufficiently characterised in relation to the claimed effect. The claimed effect, reduction of post-prandial glycaemic responses (as long as post...

  16. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to non-digestible carbohydrates and reduction of post-prandial glycaemic responses pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Beneo-Orafti SA, Sensus BV and Cosucra-Groupe Warcoing SA, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA......) was asked to deliver an opinion on the scientific substantiation of a health claim related to fructo-oligosaccharides (FOS) from inulin and a reduction of post-prandial glycaemic responses. Non-digestible carbohydrates including FOS are resistant to hydrolysis and absorption in the small intestine and do...... not contribute to post-prandial glycaemia. This opinion applies to non-digestible carbohydrates (e.g. non-starch polysaccharides, resistant oligosaccharides and resistant starch) which should replace sugars in foods or beverages in order to obtain the claimed effect. The Panel considers that the food constituent...

  17. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to AlphaGOS® and a reduction of post-prandial glycaemic responses pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    physiological effect. A claim on non-digestible carbohydrates and reduction of post-prandial glycaemic responses has already been assessed by the Panel with a favourable outcome. The previous evaluation, including the proposed wording and the conditions of use, also applies to this application. The Panel......Following an application from Olygose, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... substantiation of a health claim related to AlphaGOS® and a reduction of post-prandial glycaemic responses. Non-digestible carbohydrates, including α-galacto-oligosaccharides in AlphaGOS®, are resistant to hydrolysis and absorption in the small intestine and therefore do not contribute to post-prandial glycaemia...

  18. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to high-fibre sourdough rye bread and reduction of post-prandial glycaemic responses pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Oy Karl Fazer AB, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Finland, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion...... responses when compared with glucose. The Panel also notes that, when comparable amounts of available carbohydrates from different carbohydrate-containing foods are tested, almost any carbohydrate-containing food would induce a reduction of post-prandial blood glucose responses compared with glucose....... In addition, foods containing low amounts of, or no available carbohydrates, will also induce lower post-prandial blood glucose responses when compared with glucose. The Panel concludes that a cause and effect relationship has been established between the consumption of almost any food and a reduction of post...

  19. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to carbohydrate solutions and maintenance of physical performance during endurance exercise pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to carbohydrate solutions and maintenance of physical performance during endurance exercise. The food, which is proposed by the applicant to be the subject of the health claim, is “carbohydrate solutions...... were provided by the applicant for the scientific substantiation of this health claim. The Panel considers that these meta-analyses cannot be used to substantiate a claim on the effect of carbohydrate solutions on the maintenance of physical performance during endurance exercise as compared to water......Following an application from the British Specialist Nutrition Association Ltd, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the EFSA Panel on Dietetic Products, Nutrition and Allergies...

  20. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to Nutriose®06 and a reduction of post-prandial glycaemic responses pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    applies to this application. The Panel concludes that a cause and effect relationship has been established between the consumption of foods/beverages containing non-digestible carbohydrates and a reduction of post-prandial glycaemic responses as compared with foods/beverages containing glycaemic......Following an application from Roquette Italia S.P.A., submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion...... on the scientific substantiation of a health claim related to Nutriose®06 and a reduction of post-prandial glycaemic responses. Non-digestible carbohydrates, including resistant dextrin in Nutriose®06, are resistant to hydrolysis and absorption in the small intestine and therefore do not contribute to post...

  1. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies ), 2015. Scientific opinion on vitamin D and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked...... in the functioning of the immune system applies to all ages, including infants and young children (from birth to three years of age). The Panel concludes that a cause and effect relationship has been established between the dietary intake of vitamin D and contribution to the normal function of the immune system....... The following wording reflects the scientific evidence: ‘Vitamin D contributes to the normal function of the immune system.’ The target population is infants and young children up to three years of age....

  2. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to iron and contribution to normal formation of haemoglobin and red blood cells pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... physiological effect for infants and young children. A claim on iron and contribution to normal formation of haemoglobin and red blood cells in the general population has already been assessed by the Panel with a favourable outcome. The Panel considers that the role of iron in normal formation of haemoglobin...... and red blood cells applies to all ages, including infants and young children (from birth to three years). The Panel concludes that a cause and effect relationship has been established between dietary intake of iron and contribution to normal formation of haemoglobin and red blood cells....

  3. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on the substantiation of a health claim related to riboflavin (vitamin B2) and contribution to normal energy-yielding metabolism pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... effect for infants and young children. A claim on riboflavin and contribution to normal energy-yielding metabolism in the general population has already been assessed with a favourable outcome. The Panel notes that the role of riboflavin on normal energy-yielding metabolism applies to all ages, including...... infants and young children (from birth to three years). The Panel concludes that a cause and effect relationship has been established between the dietary intake of riboflavin and contribution to normal energy-yielding metabolism....

  4. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014 . Scientific Opinion on the substantiation of a health claim related to vitamin D and contribution to normal bone and tooth development pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... for infants and young children. A claim on vitamin D and maintenance of normal bones and teeth in the general population has already been assessed with a favourable outcome. The Panel considers that the role of vitamin D in bone and tooth mineralisation and homeostasis applies to all ages, including infants...... and young children (from birth to three years). The Panel concludes that a cause and effect relationship has been established between the dietary intake of vitamin D and contribution to normal development of bones and teeth....

  5. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to iodine and contribution to normal thyroid function pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... substantiation of a health claim related to iodine and contribution to normal thyroid function. The food constituent, iodine, which is the subject of the health claim, is sufficiently characterised. Contribution to normal thyroid function is a beneficial physiological effect for infants and young children....... A claim on iodine and normal thyroid function in the general population has already been assessed with a favourable outcome. The Panel considers that the role of iodine on normal thyroid function applies to all ages, including infants and young children (from birth to three years). The Panel concludes...

  6. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on the substantiation of a health claim related to pantothenic acid and contribution to normal energy-yielding metabolism pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked......-yielding metabolism is a beneficial physiological effect for infants and young children. A claim on pantothenic acid and normal energy-yielding metabolism in the general population has already been assessed with a favourable outcome. The Panel notes that the role of pantothenic acid in normal energy......-yielding metabolism applies to all ages, including infants and young children (from birth to three years). The Panel concludes that a cause and effect relationship has been established between the dietary intake of pantothenic acid and contribution to normal energy-yielding metabolism....

  7. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the substantiation of a health claim related to prunes and contribution to normal bowel function pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific...... for infants and young children from six months to three years of age. No evidence was provided by the applicant to substantiate the effect of prunes on bowel function without the occurrence of diarrhoea for infants and young children. The Panel concludes that a cause and effect relationship has not been...... established between the consumption of prunes and contribution to normal bowel function without the occurrence of diarrhoea for infants and young children from six months to three years of age....

  8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to polyphenols in olive and maintenance of normal blood HDL-cholesterol concentrations (ID 1639, further assessment) pursuant to Article 13(1) of Regulation (EC

    DEFF Research Database (Denmark)

    Tetens, Inge

    and maintenance of normal blood HDL-cholesterol concentrations. The food constituent, polyphenols in olive (olive fruit, olive mill waste waters or olive oil, Olea europaea L. extract and leaf) standardised by their content of hydroxytyrosol and its derivatives (e.g. oleuropein complex), that is the subject...... was insufficient to establish a cause and effect relationship between the consumption of olive oil polyphenols (standardised by the content of hydroxytyrosol and its derivatives) and maintenance of normal blood HDL cholesterol concentrations.......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to provide a scientific opinion on a health claim pursuant to Article 13 of Regulation (EC) No 1924/2006 in the framework of further assessment related to polyphenols in olive...

  9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to spermidine and contribution to normal hair growth (ID 1705) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to spermidine and contribution to normal hair growth. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health....... On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of spermidine and contribution to normal hair growth....

  10. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to acetyl-L-carnitine and contribution to normal cognitive function (ID 1432) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to acetyl-L-carnitine and contribution to normal cognitive function. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... be drawn for the scientific substantiation of the claim. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of acetyl-L-carnitine and contribution to normal cognitive function....

  11. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to ribose and faster recovery from muscle fatigue after exercise (ID 4226) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to ribose and faster recovery from muscle fatigue after exercise. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... conducted after intense intermittent training. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of ribose and faster recovery from muscle fatigue after exercise....

  12. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to sodium bicarbonate and maintenance of normal blood pressure (ID 1404) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to sodium bicarbonate and maintenance of normal blood pressure. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... substantiation of the claim. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of sodium bicarbonate and maintenance of normal blood pressure....

  13. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to fructo-oligosaccharides (FOS) and decreasing potentially pathogenic gastro-intestinal microorganisms (ID 781), pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to fructo-oligosaccharides and decreasing potentially pathogenic gastro-intestinal microorganisms. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... conclusions could be drawn for the scientific substantiation of the claim were provided. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of fructo-oligosaccharides and decreasing potentially pathogenic gastro...

  14. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to xanthan gum and changes in bowel function (ID 837) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to xanthan gum and changes in bowel function. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health....... No human studies were provided from which conclusions could be drawn for the scientific substantiation of the claim. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of xanthan gum and changes in bowel function....

  15. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to sodium phosphate and increase in endurance performance (ID 318, 2887) and increase in endurance capacity (ID 318, 2887) pursuant to Article 13(1) of Regulation (EC

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to sodium phosphate and increase in endurance performance and increase in endurance capacity. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member...... States or directly from stakeholders. The food constituent that is the subject of the health claims is sodium phosphate. The Panel considers that sodium phosphate is sufficiently characterised....

  16. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to lactose and increase in calcium absorption leading to an increase in calcium retention (ID 668) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to lactose and increase in calcium absorption leading to an increase in calcium retention. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member...... States or directly from stakeholders. The food constituent that is the subject of the health claim is lactose. The Panel considers that lactose is sufficiently characterised. The claimed effect is “calcium absorption”. The target population is assumed to be the general population. The Panel notes...

  17. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to linoleic acid (LA) in combination with gamma-linolenic acid (GLA) and reduction of ocular dryness (ID 4274) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to linoleic acid (LA) in combination with gamma-linolenic acid (GLA) and reduction of ocular dryness. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from...... Member States or directly from stakeholders. The food that is the subject of the health claims is linoleic acid in combination with gamma-linolenic acid. The Panel considers that the food constituents, linoleic acid and gamma-linolenic acid, are sufficiently characterised. The claimed effect is “ocular...

  18. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to fats and “function of the cell membrane” (ID 622, 2900, 2911) and normal absorption of fat-soluble vitamins (ID 670, 2902) pursuant to Article 13(1) of Regulation (EC

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to fats and “function of the cell membrane” and normal absorption of fat-soluble vitamins. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member...... States or directly from stakeholders. The food constituent that is the subject of the health claims is fats. The Panel considers that fats are sufficiently characterised in relation to the claimed effects....

  19. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to acetic acid and maintenance of normal blood pressure (ID 1447) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to acetic acid and maintenance of normal blood pressure. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders...... characterised. The claimed effect is “helps maintain vascular health”. The target population is assumed to be the general population. In the context of the clarifications provided by Member States, the Panel assumes that the claimed effect refers to the maintenance of normal blood pressure. The Panel considers...

  20. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to arabinoxylan produced from wheat endosperm and reduction of post-prandial glycaemic responses (ID 830) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of a health...... claim in relation to arabinoxylan produced from wheat endosperm and reduction of post-prandial glycaemic responses. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from...... Member States or directly from stakeholders. The food constituent that is the subject of the health claim is “wheat grain fibre”. From the references and information provided, the Panel assumes that the food constituent that is responsible for the claimed effect is arabinoxylan from wheat endosperm...

  1. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to oat and barley grain fibre and increase in faecal bulk (ID 819, 822) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to oat and barley grain fibre and increase in faecal bulk. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders....... In the context of the clarifications provided by Member States and the references provided, the Panel assumes that the claimed effect refers to the improvement of bowel function by increasing faecal bulk. The Panel considers that an increase in faecal bulk may be a beneficial physiological effect. In weighing...

  2. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to a combination of lycopene, vitamin E, lutein and selenium and “ helps to prepare and activate tannin g ” pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Cyprus, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim...... related to a combination of lycopene, vitamin E, lutein and selenium and “helps to prepare and activate tanning”. The Panel considers that the combination of lycopene, vitamin E, lutein and selenium is sufficiently characterised. The claimed effect proposed by the applicant is “helps to prepare...... and activate tanning”. Tanning (i.e. increasing the pigmentation of the skin) may contribute to the protection of the skin against UV-induced damage. The Panel considers that protection of the skin from UV-induced (including photo-oxidative) damage is a beneficial physiological effect. A claim on a combination...

  3. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014. Scientific Opinion on the modification of the authorisation of a health claim related to cocoa flavanols and maintenance of normal endotheliumdependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924

    DEFF Research Database (Denmark)

    Tetens, Inge

    of the authorisation of a health claim related to “cocoa flavanols help maintain the elasticity of blood vessels, which contributes to normal blood flow”, pursuant to Article 13(5) of Regulation (EC) No 1924/2006. The modification concerns an extension of the authorised conditions of use of the claim to a high......-flavanols (HF) cocoa extract to be consumed in capsules, tablets or added to “other foods, including beverages”. Cocoa flavanols, which are the subject of the health claim, have been sufficiently characterised. Maintenance of normal endothelium-dependent vasodilation is a beneficial physiological effect....... The Panel concludes that a cause and effect relationship has been established between the consumption of cocoa flavanols in the HF cocoa extract (i.e. in capsules or tablets) and maintenance of normal endothelium-dependent vasodilation. In order to obtain the claimed effect, 200 mg of cocoa flavanols should...

  4. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to EffEXT™ and “helps to support joint function by maintaining low levels of plasma C-reactive protein” pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim...... related to EffEXT™ and “helps to support joint function by maintaining low levels of plasma C‑reactive protein”. The Panel considers that EffEXT™, which is standardised pure krill oil, is sufficiently characterised. The claimed effect is “helps to support joint function by maintaining low levels of plasma...... C-reactive protein”. The Panel notes that the claim refers to a reduction of inflammation indicated by a lowered concentration of plasma C-reactive protein. Whether or not reduction of inflammatory markers is considered beneficial depends on the context in which a claim is made. In the context...

  5. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to glucose and contribution to energy-yielding metabolism pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claim related to glucose and “contributes to normal muscle function”. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food constituent that is the subject of the health claim is glucose, which is sufficiently characterised......Following an application from Dextro Energy GmbH & Co. KG, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health....... The claimed effect is “contributes to normal muscle function”. The proposed target population is healthy, active, as well as endurance trained, men and women. The Panel notes that the claimed effect refers to the contribution of the food constituent to energy-yielding metabolism in active individuals. Energy...

  6. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to glucose and contribution to energy-yielding metabolism pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claim related to glucose and “contributes to normal energy-yielding metabolism during exercise”. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food constituent that is the subject of the health claim is glucose, which......Following an application from Dextro Energy GmbH & Co. KG, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health...... is sufficiently characterised. The claimed effect is “contributes to normal energy-yielding metabolism during exercise”. The proposed target population is healthy, active, as well as endurance trained, men and women. The Panel notes that the claimed effect refers to the contribution of the food constituent...

  7. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2014 . Scientific Opinion on the substantiation of a health claim related to selenium and protection of DNA, proteins a nd lipids from oxidative damage pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked...... to deliver an opinion on the scientific substantiation of a health claim related to selenium and protection of DNA, proteins and lipids from oxidative damage. The Panel considers that selenium is sufficiently characterised. Protection of body cells and molecules such as DNA, proteins and lipids from...... oxidative damage is a beneficial physiological effect. The Panel has previously assessed a claim on selenium and protection of DNA, proteins and lipids from oxidative damage with a favourable outcome. The target population was the general population. The Panel considers that the role of selenium...

  8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to calcium and potassium and maintenance of normal acid-base balance (ID 400, 407) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to calcium and potassium and maintenance of normal acid-base balance. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from...... stakeholders. The food constituents that are the subject of the health claims are calcium and potassium. The Panel considers that calcium and potassium are sufficiently characterised. The claimed effects are “calcium contributes to acid/base balance within metabolism” and “mineral/potassium: key function...

  9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to sugar-free chewing gum with calcium phosphoryl oligosaccharides and maintenance of tooth mineralisation (ID 337) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to sugar-free chewing gum with calcium phosphoryl oligosaccharides and maintenance of tooth mineralisation. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received...... from Member States or directly from stakeholders. The food constituent that is the subject of the health claim is calcium phosphoryl oligosaccharides. In the context of the references provided, the Panel assumes that the food, which is the subject of the health claim is sugar-free chewing gum...

  10. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to glucose and contribution to energy-yielding metabolism pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Dextro Energy GmbH & Co. KG submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health...... claim related to glucose and “it is metabolised within body’s normal energy metabolism”. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food constituent that is the subject of the health claim is glucose, which is sufficiently...... in energy-yielding metabolism as a source of energy. The Panel concludes that a cause and effect relationship has been established between the intake of glucose and contribution to energy-yielding metabolism. The following wording reflects the scientific evidence: “glucose contributes to energy...

  11. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to “αS1-casein tryptic hydrolysate” and alleviation of psychological stress (ID 656, 1819, 4253) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to “αS1-casein tryptic hydrolysate” and alleviation of psychological stress. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly...... to calm mind”, “mental state and performance”, and “stress”. The target population is assumed to be the general population. In the context of the proposed wordings and from the references provided, the Panel assumes that the claimed effects refer to alleviation of psychological stress. The Panel considers...

  12. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to carbonate and bicarbonate salts of sodium and potassium and maintenance of normal bone (ID 331, 1402) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health cla...... the dietary intake of carbonate or bicarbonate salts of sodium or potassium and maintenance of normal bone....... claims in relation to carbonate and bicarbonate salts of sodium and potassium and maintenance of normal bone. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member...... States or directly from stakeholders. The food constituents that are the subject of the health claim are carbonate and bicarbonate salts of sodium and potassium. The Panel considers that carbonate and bicarbonate salts of sodium and potassium are sufficiently characterised. The claimed effects are “acid...

  13. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to flaxseed oil and vitamin E and maintenance of the skin permeability barrier function pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim....... The applicant identified two published human intervention studies as being pertinent to the health claim. Owing to the very limited information provided regarding key methodological aspects, and to the important limitations of the statistical analysis performed, the Panel considers that no conclusions can...... be drawn from these studies for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of flaxseed oil and vitamin E and maintenance of the skin permeability barrier function...

  14. Public Availability to ECS Collected Datasets

    Science.gov (United States)

    Henderson, J. F.; Warnken, R.; McLean, S. J.; Lim, E.; Varner, J. D.

    2013-12-01

    Coastal nations have spent considerable resources exploring the limits of their extended continental shelf (ECS) beyond 200 nm. Although these studies are funded to fulfill requirements of the UN Convention on the Law of the Sea, the investments are producing new data sets in frontier areas of Earth's oceans that will be used to understand, explore, and manage the seafloor and sub-seafloor for decades to come. Although many of these datasets are considered proprietary until a nation's potential ECS has become 'final and binding' an increasing amount of data are being released and utilized by the public. Data sets include multibeam, seismic reflection/refraction, bottom sampling, and geophysical data. The U.S. ECS Project, a multi-agency collaboration whose mission is to establish the full extent of the continental shelf of the United States consistent with international law, relies heavily on data and accurate, standard metadata. The United States has made it a priority to make available to the public all data collected with ECS-funding as quickly as possible. The National Oceanic and Atmospheric Administration's (NOAA) National Geophysical Data Center (NGDC) supports this objective by partnering with academia and other federal government mapping agencies to archive, inventory, and deliver marine mapping data in a coordinated, consistent manner. This includes ensuring quality, standard metadata and developing and maintaining data delivery capabilities built on modern digital data archives. Other countries, such as Ireland, have submitted their ECS data for public availability and many others have made pledges to participate in the future. The data services provided by NGDC support the U.S. ECS effort as well as many developing nation's ECS effort through the U.N. Environmental Program. Modern discovery, visualization, and delivery of scientific data and derived products that span national and international sources of data ensure the greatest re-use of data and

  15. Scientific Opinion on the substantiation of a health claim related to eicosapentanoic acid (EPA and “reduces the AA/EPA ratio in blood. A high AA/EPA level is a risk factor in the development of attention difficulties in children with ADHD-like symptoms” pursuant to Article 14 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-04-01

    Full Text Available Following an application from Minami Nutrition Health BVBA, submitted pursuant to Article 14 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to eicosapentaenoic acid (EPA and “reduces the AA/EPA ratio in blood. A high AA/EPA level is a risk factor in the development of attention difficulties in children with attention deficit hyperactivity disorder (ADHD-like symptoms”. The food constituent, EPA, which is the subject of the health claim, is sufficiently characterised. The claimed effect proposed by the applicant is “reduces the AA/EPA ratio in blood. A high AA/EPA level is a risk factor in the development of attention difficulties in children with ADHD-like symptoms. These children are also characterised by less hyperactivity and/or coexisting oppositional behaviour”. Upon a request by EFSA for clarification, the applicant indicated that the disease was ADHD, which is classified as such in accordance with the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, that the risk factor for the disease was an elevated AA/EPA ratio in blood, and that the target population for the claim was children with diagnosis of ADHD. The Panel considers that the evidence provided does not establish that reducing the AA/EPA ratio reduces the risk of ADHD in children, and considers that the target population is a diseased population (i.e. children with ADHD. The Panel concludes that the claimed effect relates to the treatment of a disease, and that therefore the health claim does not comply with the criteria laid down in Regulation (EC No 1924/2006.

  16. Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis.

    Science.gov (United States)

    Teoh-Fitzgerald, M L; Fitzgerald, M P; Zhong, W; Askeland, R W; Domann, F E

    2014-01-16

    Expression of the antioxidant enzyme EcSOD in normal human mammary epithelial cells was not recognized until recently. Although expression of EcSOD was not detectable in non-malignant human mammary epithelial cells (HMEC) cultured in conventional two-dimensional (2D) culture conditions, EcSOD protein expression was observed in normal human breast tissues, suggesting that the 2D-cultured condition induces a repressive status of EcSOD gene expression in HMEC. With the use of laminin-enriched extracellular matrix (lrECM), we were able to detect expression of EcSOD when HMEC formed polarized acinar structures in a 3D-culture condition. Repression of the EcSOD-gene expression was again seen when the HMEC acini were sub-cultured as a monolayer, implying that lrECM-induced acinar morphogenesis is essential in EcSOD-gene activation. We have further shown the involvement of DNA methylation in regulating EcSOD expression in HMEC under these cell culture conditions. EcSOD mRNA expression was strongly induced in the 2D-cultured HMEC after treatment with a DNA methyltransferase inhibitor. In addition, epigenetic analyses showed a decrease in the degree of CpG methylation in the EcSOD promoter in the 3D versus 2D-cultured HMEC. More importantly, >80% of clinical mammary adenocarcinoma samples showed significantly decreased EcSOD mRNA and protein expression levels compared with normal mammary tissues and there is an inverse correlation between the expression levels of EcSOD and the clinical stages of breast cancer. Combined bisulfite restriction analysis analysis of some of the tumors also revealed an association of DNA methylation with the loss of EcSOD expression in vivo. Furthermore, overexpression of EcSOD inhibited breast cancer metastasis in both the experimental lung metastasis model and the syngeneic mouse model. This study suggests that epigenetic silencing of EcSOD may contribute to mammary tumorigenesis and that restoring the extracellular superoxide scavenging

  17. Two-component system YvqEC-dependent bacterial resistance against vancomycin in Bacillus thuringiensis.

    Science.gov (United States)

    Zhang, Shumeng; Hu, Yimin; Fan, Qingyun; Wang, Xun; He, Jin

    2015-08-01

    YvqEC is one of the two-component signal transduction systems that may respond to cell envelope stress and enable cells to adjust multiple cellular functions. It consists of a histidine kinase YvqE and a response regulator YvqC. In this study, we separately constructed a single gene mutant ΔyvqE and a double gene mutant ΔyvqEC in Bacillus thuringiensis BMB171 through a homing endonucleases I-SceI mediated markerless gene deletion method. We found that the deletion of either yvqE or yvqEC weakened the resistance of B. thuringiensis against vancomycin. We also identified nine operons that may be involved in the cellular metabolism regulated by YvqC. This study not only enriches our understanding of bacterial resistance mechanisms against vancomycin, but also helps investigate the functions of YvqEC.

  18. Council Chamber exhibition

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    To complete the revamp of CERN’s Council Chamber, a new exhibition is being installed just in time for the June Council meetings.   Panels will showcase highlights of CERN’s history, using some of the content prepared for the exhibitions marking 50 years of the PS, which were displayed in the main building last November. The previous photo exhibition in the Council Chamber stopped at the 1970s. To avoid the new panels becoming quickly out of date, photos are grouped together around specific infrastructures, rather than following a classic time-line. “We have put the focus on the accelerators – the world-class facilities that CERN has been offering researchers over the years, from the well-known large colliders to the lesser-known smaller facilities,” says Emma Sanders, who worked on the content. The new exhibition will be featured in a future issue of the Bulletin with photos and an interview with Fabienne Marcastel, designer of the exhibit...

  19. DECLARATION TO COUNCIL

    CERN Multimedia

    Staff Association

    2015-01-01

    One year ago, the Staff Association, together with the CERN-ESO Pensioners' Association, organized a staff meeting in front of this building to express our concern about certain actions of this Committee. Today we deem it necessary to come before you and convey in person, dear delegates, the concerns and worries of the staff. Indeed, the last 18 months we have observed a tendency of Council to take matters, in particular in the field of pensions, into its own hands, bypassing established governance structures, which Council has itself put into place. As a result, the Director General was prevented from playing his essential role of intermediary between staff and Council, an essential element of the established social dialogue. The creation of CERN in 1954 was very much based on the willingness of many countries of the old Continent to share resources to create a joint fundamental physics laboratory. The emphasis was on sharing resources for the common good to allow European scientists to engage in...

  20. Elections to Staff Council

    CERN Multimedia

    Staff Association

    2013-01-01

    Elections to fill all seats in the Staff Council are being organized this month. The voting takes place from the 28 of October to the 11th of November, at noon. As you may have noted when reading Echo, many issues concerning our employment conditions are on the agenda of the coming months, and in particular the Five-yearly-Review 2015, subject of the questionnaire that you probably recently filled out. All this will keep the next Staff Council very busy indeed. So, make your voice heard and take part in the elections for a new Staff Council. By doing so, you will be encouraging the men and women who will be representing you over the next two years and they will doubtless appreciate your gratitude. Every member of the Staff Association will have received an email containing a link to the webpage which will allow voting. If you are a member of the Staff Association and you did not receive such an email, please contact the Staff Association secretariat (staff.association@cern.ch). Do not forget to v...

  1. Highlights: Spring Council Meeting

    Science.gov (United States)

    Council members present at the May 24, 1981, meeting were Keiiti Aki, Steven Burges (for Jim Wallis), Peter S. Eagleson, E. R. Engdahl, Charles E. Helsley, James R. Heirtzler, Carl Kisslinger, Leslie H. Meredith, Chris N. K. Mooers, Norman F. Ness, Marcia M. Neugebauer, James J. O'Brien, Richard Rapp, Carl Sagan, James C. Savage, Joseph V. Smith, Fred Spilhaus, Donald L. Turcotte, James A. Van Allen, J. Tuzo Wilson, and Jay Winston (for Elmar R. Reiter until his arrival at 6:50 P.M.). David Strangway, representing the Canadian Geophysical Union, and Peter Steinhauser, representing the European Geophysical Society, were special observers at the meeting. Council meetings are open, and a number of section secretaries, committee chairmen, journal editors, and other members attended. The following major actions were adopted by the Council:The experiment of publishing oceanography and lower-atmosphere papers in JGR Green issues alternate to those containing upper-atmosphere papers will be continued through 1982. From preliminary indications the experiment seems to be working, but a full year of data, including a renewal cycle, is needed to assess the success of the experiment. Final decision will be made prior to the 1983 dues notices.

  2. IUDs as EC? Limited awareness and high reported acceptability: evidence from Argentina.

    Science.gov (United States)

    Pichardo, Margaret; Arribas, Lia; Coccio, Elina; Heredia, Graciela; Jagroep, Sherani; Palermo, Tia

    2014-11-01

    We explored knowledge and attitudes regarding the copper intrauterine device (IUD) as emergency contraception (EC) among women in Buenos Aires, Argentina. We interviewed a convenience sample of women attending a family planning center at a public hospital. Participants were asked about knowledge and use of contraceptives, including EC (pre-script). Then they were given information about the IUD as EC and subsequently asked about acceptability of using the copper IUD as EC (post-script), the primary outcome in this analysis. We analyzed data on 273 women. While only 1.83% of participants knew the IUD served as EC at baseline, 79.85% said they would be willing to use the device as such if the need arose after given relevant information. Multivariate results from a pre-script revealed that women with low levels of education and those born outside of Argentina were less knowledgeable about EC pills. Only previous use of the IUD was associated with high levels of IUD knowledge. Post-script, results indicated that being Argentine [odds ratio (OR)=2.15, 95% confidence interval (CI) 1.21, 3.81] and previous IUD use (OR=2.12, 95% CI=1.07, 4.19) were positively associated with considering the IUD as EC. Nulliparity was negatively associated with willingness to use the IUD as EC (OR=0.44, 95% CI 0.22, 0.86). We examined acceptability of the copper IUD as EC in a Latin American setting and found that, while prior levels of knowledg'e were low, acceptability of the IUD as EC was high. Implications for programming and policy include outreach and education regarding this highly effective method and advocacy to change existing regulations in Argentina prohibiting the use of IUD as EC. After given information about the IUD as a method of EC, women interviewed said they would be willing to use the IUD EC despite their limited prior knowledge of this method. With more widespread information and availability of the IUD as EC, more women may opt for this highly effective method, which

  3. The EC discourse on vocational training

    DEFF Research Database (Denmark)

    Cort, Pia

    2009-01-01

    This article traces the EC vocational training policy historically and describes the discursive alignments which brought the policy from a ‘common vocational training policy' as laid down in Article 128, in the Treaty of Rome to the Lisbon Lifelong Learning strategy. The argument is that vocational...... training has served as a lever for the gradual expansion of the policy field into both general and higher education and for the establishment of a European discourse on Lifelong Learning. In the article, Ball's concept of "policy as discourse" is used to identify the changing spaces of possibility within...... EC vocational training policy (Ball, What is policy? Texts, trajectories and toolboxes. Discourse, 13(2), 1993)....

  4. Preliminary conceptual design of DEMO EC system

    Energy Technology Data Exchange (ETDEWEB)

    Garavaglia, S., E-mail: garavaglia@ifp.cnr.it; Bin, W.; Bruschi, A.; Granucci, G.; Moro, A.; Rispoli, N. [Institute of Plasma Physics “P.Caldirola”, National Research Council of Italy, Milan (Italy); Grossetti, G.; Strauss, D. [IAM-AWP, Kaiserstr. 12, D-76131 Karlsruhe (Germany); Jelonnek, J. [IHM, KIT, Kaiserstr. 12, D-76131 Karlsruhe (Germany); Tran, Q. M. [CRPP, EPFL, EURATOM Association, CH-1015 Lausanne (Switzerland); Franke, T. [EUROfusion Consortium, Boltzmannstr. 2, D-85748 Garching (Germany); Max-Planck-Institut für Plasmaphysik, Garching (Germany)

    2015-12-10

    In the framework of EUROfusion Consortium the Work Package Heating and Current Drive addresses the engineering design and R&D for the electron cyclotron, ion cyclotron and neutral beam systems. This paper reports the activities performed in 2014, focusing on the work done regarding the input for the conceptual design of the EC system, particularly for the gyrotron, the transmission line and the launchers.

  5. Gorbachev’s Presidential Council

    Science.gov (United States)

    1990-08-01

    writer Valentin Rasputin told a Literaturnaya gazeta editor that his presence, and that of Chingis Aitmatov, on the Council was to ensure that the...president hear "another language a writer’s language." Also. Rasputin said, he would be able to convey to the president "specific Russian interests...and abroad. "It is very important." Council member Rasputin explains, "that the Presidential Council anticipates the probability of a critical

  6. Ecdysone Receptor (EcR Is Involved in the Transcription of Cell Cycle Genes in the Silkworm

    Directory of Open Access Journals (Sweden)

    Wenliang Qian

    2015-02-01

    Full Text Available EcR (ecdysone receptor-mediated ecdysone signaling pathway contributes to regulate the transcription of genes involved in various processes during insect development. In this work, we detected the expression of EcR gene in silkworm ovary-derived BmN4 cells and found that EcR RNAi result in an alteration of cell shape, indicating that EcR may orchestrate cell cycle progression. EcR RNAi and EcR overexpression analysis revealed that in the cultured BmN4 cells, EcR respectively promoted and suppressed the transcription of E2F-1 and CycE, two genes controlling cell cycle progression. Further examination demonstrated that ecdysone application in BmN4 cells not only changed the transcription of these two cell cycle genes like that under EcR overexpression, but also induced cell cycle arrest at G2/M phase. In vivo analysis confirmed that E2F-1 expression was elevated in silk gland of silkworm larvae after ecdysone application, which is same as its response to ecdysone in BmN4 cells. However, ecdysone also promotes CycE transcription in silk gland, and this is converse with the observation in BmN4 cells. These results provide new insights into understanding the roles of EcR-mediated ecdysone signaling in the regulation of cell cycle.

  7. 7 CFR 1260.312 - Remittance to the Cattlemen's Board or Qualified State Beef Council.

    Science.gov (United States)

    2010-01-01

    ... State Beef Council. 1260.312 Section 1260.312 Agriculture Regulations of the Department of Agriculture...), DEPARTMENT OF AGRICULTURE BEEF PROMOTION AND RESEARCH Rules and Regulations § 1260.312 Remittance to the Cattlemen's Board or Qualified State Beef Council. Each person responsible for the collection and...

  8. News from Council

    CERN Multimedia

    2016-01-01

    With this message I would like to share with you some highlights of this week’s Council meetings.   A major topic was the approval of CERN’s Medium Term Plan (MTP) 2017-2021, along with the budget for 2017. In approving the document, Council expressed its very strong support for the research programme the MTP outlines for the coming years.  Another important topic this week was the formal approval of the High Luminosity LHC project, HL-LHC. This comes as extremely good news not only for CERN, but also for particle physics globally. HL-LHC is the top priority of the European Strategy for Particle Physics in its 2013 update, and is part of the 2016 roadmap of the European Strategy Forum on Research Infrastructures, ESFRI. It was also identified as a priority in the US P5 strategy process, and in Japan’s strategic vision for the field. It secures CERN’s future until 2035, and ensures that we will achieve the maximum scientific return on the investment...

  9. 76 FR 542 - Pacific Fishery Management Council (Council); Public Meeting

    Science.gov (United States)

    2011-01-05

    ... Council (Pacific Council) will convene a meeting of the Ecosystem Plan Development Team (EPDT) which is.... SUPPLEMENTARY INFORMATION: Please note, this is not a public hearing; it is a work session for the primary... that may benefit from a coordinated overarching EFMP framework. A draft version of an EPDT...

  10. 75 FR 71417 - Manufacturing Council Membership

    Science.gov (United States)

    2010-11-23

    ... International Trade Administration Manufacturing Council Membership AGENCY: International Trade Administration... Manufacturing Council. SUMMARY: The Department of Commerce is currently seeking applications to fill one vacant position on the Manufacturing Council (Council). The purpose of the Council is to advise the Secretary of...

  11. Q and A. Why the EC's PINC has failed Europe's nuclear industry

    Energy Technology Data Exchange (ETDEWEB)

    Kraev, Kamen [NucNet, Brussels (Belgium)

    2016-12-15

    The European Economic and Social Committee (EESC) has called for a more comprehensive strategy to be incorporated in a revised version of the European Commission's (EC) Illustrative Programme for Nuclear Energy (PINC). EESC member Brian Curtis tells NucNet why the PINC has failed to address key issues for nuclear and why he believes the EC has become side-tracked by renewables. The EESC is a consultative body which represents the interests of civil society organisations and stakeholders at the EU. Its opinions are forwarded to the EC, the European Council, and the European Parliament and are considered in the EU's decision-making process. Brian Curtis was rapporteur on the committee's opinion paper.

  12. Trump revives National Space Council

    Science.gov (United States)

    Johnston, Hamish

    2017-08-01

    US president Donald Trump has signed an executive order to re-establish the US National Space Council. The 12-member council will include key government officials with an interest in space exploration, including NASA’s acting administrator Robert Lightfoot and the secretaries of state, commerce and defence.

  13. 75 FR 12507 - Manufacturing Council

    Science.gov (United States)

    2010-03-16

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an opportunity to apply for membership on the Manufacturing Council. SUMMARY: The Department of Commerce is currently seeking applications for membership on the Manufacturing...

  14. [International regulation of ethics committees on biomedical research as protection mechanisms for people: analysis of the Additional Protocol to the Convention on Human Rights and Biomedicine, concerning Biomedical Research of the Council of Europe].

    Science.gov (United States)

    de Lecuona, Itziar

    2013-01-01

    The article explores and analyses the content of the Council of Europe's Additional Protocol to the Convention on Human Rights and Biomedicine concerning Biomedical Research regarding the standard legal instrument in biomedical research, issued by an international organization with leadership in bioethics. This implies ethics committees are mechanisms of protection of humans in biomedical research and not mere bureaucratic agencies and that a sound inescapable international regulatory framework exists for States to regulate biomedical research. The methodology used focuses on the analysis of the background, the context in which it is made and the nature and scope of the Protocol. It also identifies and analyses the characteristics and functions of ethics committees in biomedical research and, in particular, the information that should be provided to this bodies to develop their functions previously, during and at the end of research projects. This analysis will provide guidelines, suggestions and conclusions for the awareness and training of members of these committees in order to influence the daily practice. This paper may also be of interest to legal practitioners who work in different areas of biomedical research. From this practical perspective, the article examines the legal treatment of the Protocol to meet new challenges and classic issues in research: the treatment of human biological samples, the use of placebos, avoiding double standards, human vulnerability, undue influence and conflicts of interest, among others. Also, from a critical view, this work links the legal responses to develop work procedures that are required for an effective performance of the functions assigned of ethics committees in biomedical research. An existing international legal response that lacks doctrinal standards and provides little support should, however, serve as a guide and standard to develop actions that allow ethics committees -as key bodies for States- to advance in

  15. Summary of ECE Presentations at EC-19

    Science.gov (United States)

    Austin, M. E.

    2017-07-01

    At the EC-19 workshop there were ten presentations in the topic of diagnosing and heating plasmas with Electron Cyclotron Emission (ECE) and Electron Bernstein Wave (EBW). Innovations continue in designs of ECE systems while tried-and-true instruments still provide adequate data to explore new areas of research. Heterodyne radiometers and Michelson interferometers carry on as the bedrock of ECE electron temperature (Te) measurements while ECE imaging systems continue expanding their capabilities. The design of the ITER-ECE diagnostic system is in its advanced stages; solutions are being found for challenges in the transmission lines and front-end calibration sources.

  16. Scientific Opinion on the substantiation of a health claim related to a combination of thiamin, riboflavin, niacin, pantothenic acid, pyridoxine, D-biotin and pumpkin seed oil and maintenance of normal hair pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following two applications from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of thiamin, riboflavin, niacin, pantothenic acid, pyridoxine, D-biotin and pumpkin seed oil (Cucurbita pepo L. and maintenance of normal hair. The Panel considers that the specified combination is sufficiently characterised. The claimed effects are “contributes to reduce hair loss” and “increases the number of hair”. The target population proposed by the applicant is healthy adults in the general population. The Panel considers that maintenance of normal hair is a beneficial physiological effect. The applicant identified one publication as being pertinent to the health claim. This study did not use the food which is the subject of the claim. No conclusions can be drawn from this study for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of thiamin, riboflavin, niacin, pantothenic acid, pyridoxine, D-biotin and pumpkin seed oil (Cucurbita pepo L. and maintenance of normal hair.

  17. Scientific Opinion on the substantiation of a health claim related to a combination of Bifidobacterium longum LA 101, Lactobacillus helveticus LA 102, Lactococcus lactis LA 103 and Streptococcus thermophilus LA 104 and improves stool frequency pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-02-01

    Full Text Available Following an application from PiLeJe submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of Bifidobacterium longum LA 101, Lactobacillus helveticus LA 102, Lactococcus lactis LA 103 and Streptococcus thermophilus LA 104 and improves stools frequency. The food that is the subject of the health claim is a combination of B. longum LA 101, L. helveticus LA 102, L. lactis LA 103 and S. thermophilus LA 104. The information provided was insufficient to establish that the strain L. lactis LA 103 was sufficiently characterised. The Panel considers that if in a combination of several microorganisms and/or ingredients one microorganism or ingredient used in the combination is not sufficiently characterised, then the combination is considered to be not sufficiently characterised. A combination of B. longum LA 101, L. helveticus LA 102, L. lactis LA 103, and S. thermophilus LA 104 is not sufficiently characterised. The Panel concludes that a cause and effect relationship cannot be established between the consumption of a combination of B. longum LA 101, L. helveticus LA 102, L. lactis LA 103 and S. thermophilus LA 104 and improves stool frequency.

  18. Scientific Opinion on the substantiation of a health claim related to Transitech® and improvement of bowel function which is maintained after cessation of consumption of the food pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-06-01

    Full Text Available Following an application from Vivatech, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to Transitech® and improvement of bowel function which is maintained after cessation of consumption of the food. The food, Transitech®, that is the subject of the health claim is sufficiently characterised. The claimed effect, improvement of bowel function which is maintained after cessation of consumption of the food, is a beneficial physiological effect. In weighing the evidence, the Panel considered that the one study that investigated the claimed effect did not show an effect of Transitech® on bowel function which is maintained after cessation of consumption of the food. A cause and effect relationship has not been established between the consumption of Transitech® and improvement of bowel function which is maintained after cessation of consumption of the food.

  19. Scientific Opinion on the substantiation of health claims related to soy isoflavones and maintenance of bone mineral density (ID 1655 and reduction of vasomotor symptoms associated with menopause (ID 1654, 1704, 2140, 3093, 3154, 3590 (further assessment pursuant to Article 13(1 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-08-01

    Full Text Available

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to provide a scientific opinion on health claims pursuant to Article 13 of Regulation (EC No 1924/2006 in the framework of further assessment related to soy isoflavones and maintenance of bone mineral density and reduction of vasomotor symptoms associated with menopause. The food constituent that is the subject of the claim, soy isoflavones, is sufficiently characterised. The claimed effects, maintenance of bone mineral density and reduction of vasomotor symptoms associated with menopause, which are eligible for further assessment, are beneficial physiological effects. The proposed target populations are peri- and/or post-menopausal women. On the basis of the data presented, the Panel concludes that the evidence provided is insufficient to establish a cause and effect relationship between the consumption of soy isoflavones and maintenance of bone mineral density, and between the consumption of soy isoflavones and reduction of vasomotor symptoms associated with menopause.

  20. Scientific Opinion on the substantiation of a health claim related to a combination of lycopene, vitamin E, lutein and selenium and “helps to prepare and activate tanning” pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-12-01

    Full Text Available Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Cyprus, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of lycopene, vitamin E, lutein and selenium and “helps to prepare and activate tanning”. The Panel considers that the combination of lycopene, vitamin E, lutein and selenium is sufficiently characterised. The claimed effect proposed by the applicant is “helps to prepare and activate tanning”. Tanning (i.e. increasing the pigmentation of the skin may contribute to the protection of the skin against UV-induced damage. The Panel considers that protection of the skin from UV-induced (including photo-oxidative damage is a beneficial physiological effect. A claim on a combination of lycopene, vitamin E, lutein and selenium and protection of the skin from UV-induced (including photo-oxidative damage has already been assessed by the Panel with an unfavourable outcome. The reference provided by the applicant for the scientific substantiation of this claim was the same as in the previous submission.

  1. Scientific Opinion on the substantiation of a health claim related to a combination of Paullinia cupana Kunth (guarana and Camellia sinensis (L. Kuntze (green tea extracts and reduction of body weight pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-12-01

    Full Text Available Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Cyprus, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of Paullinia cupana Kunth (guarana and Camellia sinensis (L. Kuntze (green tea extracts and reduction of body weight. The Panel considers that the food constituent which is the subject of the health claim is sufficiently characterised. The claimed effect, reduction of body weight, is a beneficial physiological effect for overweight subjects. One human intervention study from which no conclusions could be drawn for the scientific substantiation of the claim was provided by the applicant. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of Paullinia cupana Kunth (guarana and Camellia sinensis (L. Kuntze (green tea extracts and a reduction in body weight.

  2. Scientific Opinion on the substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood HDL-cholesterol concentrations pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted for authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood HDL-cholesterol concentrations. The food that is the subject of the health claim, OptiEFAX™, which is standardised pure krill oil, is sufficiently characterised in relation to the claimed effect. The claimed effect, maintenance of normal blood HDL-cholesterol concentrations, is a beneficial physiological effect. The target population proposed by the applicant is the general population. No human studies have been provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect relationship has not been established between the consumption of OptiEFAX™ and maintenance of normal blood HDL-cholesterol concentrations.

  3. Scientific Opinion on the substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood LDL-cholesterol concentrations pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies

    2012-07-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted for authorisation of a claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to OptiEFAX™ and maintenance of normal blood LDL-cholesterol concentrations. The food that is the subject of the health claim, OptiEFAX™, which is standardised pure krill oil, is sufficiently characterised in relation to the claimed effect. The claimed effect, maintenance of normal blood LDL-cholesterol concentrations, is a beneficial physiological effect. The target population proposed by the applicant is the general population. No human studies have been provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect relationship has not been established between the consumption of OptiEFAX™ and maintenance of normal blood LDL-cholesterol concentrations.

  4. Scientific Opinion on the substantiation of a health claim related to a combination of lycopene, vitamin E, lutein and selenium and protection of the skin from UV-induced (including photo-oxidative damage pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2012-09-01

    Full Text Available

    Following an application from Nutrilinks Sarl, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of Cyprus, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of lycopene, vitamin E, lutein and selenium and protection of the skin from UV-induced (including photo-oxidative damage. The Panel considers that the combination of lycopene, vitamin E, lutein and selenium is sufficiently characterised. The claimed effect refers to the photo-protective activity of the food, delaying the appearance of UV-induced erythema and decreasing its intensity. The target population proposed by the applicant is healthy adults in the general population, and in particular people with sensitive skin. The Panel considers that protection of the skin from UV-induced (including photo-oxidative damage is a beneficial physiological effect. The applicant identified one bioequivalence study as being pertinent to the health claim. The Panel notes that this study did not assess direct measures of UV-induced (including photo-oxidative skin damage. Therefore, no conclusions could be drawn from this study for the scientific substantiation of the claim. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of lycopene, vitamin E, lutein and selenium and protection of the skin from UV-induced (including photo-oxidative damage.

  5. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to 3 g/day plant stanols as plant stanol esters and lowering blood LDL-cholesterol and reduced risk of (coronary) heart disease pursuant to Article 14 of Regulation (EC

    DEFF Research Database (Denmark)

    Tetens, Inge

    related to 3 g/day plant stanols as plant stanol esters per day and lowering blood LDL-cholesterol by 12 % and reduced risk of (coronary) heart disease. The applicant has further requested that the minimum duration to obtain the effect be stated to be one to two weeks, and that the claims be authorised...... for an extended range of foods, including yellow fat spreads, dairy products, cheese, rye bread, oatmeal, fermented soy milk based products (drinkable and spoonable yoghurt-type products), and oat based milk drinks. The applicant provided an unpublished meta-analysis with 18 randomised, controlled human studies...... on the LDL-lowering efficacy of plant stanol esters at intakes between 2.7 to 3.3 g per day plant stanols. On the basis of the data presented, the Panel concludes that plant stanol esters at a daily intake of 3 g plant stanols (range 2.7 g to 3.3 g) in matrices approved by Regulation (EC) No 376/2010 (yellow...

  6. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to 3 g/day plant sterols/stanols and lowering blood LDL-cholesterol and reduced risk of (coronary) heart disease pursuant to Article 19 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    of an application to modify the conditions of use of an authorised Article 14 claim related to 1.5 - 3.0 g plant sterols/stanols per day and lowering blood LDL-cholesterol by 7 - 12 % and reduced risk of (coronary) heart disease. The applicant has further requested that the minimum duration to obtain the effect...... be one to two weeks. The applicant provided a published systematic review and meta-analysis that evaluated the comparative efficacy of plant sterols and plant stanols for lowering blood LDL-cholesterol in healthy and hypercholesterolaemic subjects and an unpublished meta-analysis on 27 randomised....../2010 (yellow fat spreads, dairy products, mayonnaise and salad dressings) have a similar efficacy on blood LDL-cholesterol lowering, that plant sterols and stanol esters at a daily intake of 3 g (range 2.6 g to 3.4 g) plant sterols/stanols in matrices approved by Regulation (EC) No 376/2010 lower LDL-cholesterol...

  7. 7 CFR 1230.6 - Council.

    Science.gov (United States)

    2010-01-01

    ... CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.6 Council. Council means the National Pork Producers Council, a nonprofit corporation of the type described...

  8. Government Districts, Other - MDC_CommunityCouncil

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — A polygon feature class of Miami-Dade County Community Councils. The Community Councils covers the entire unincorporated area of Miami-Dade County. Each Council has...

  9. EC Competition law and environmental protection

    Energy Technology Data Exchange (ETDEWEB)

    Rantala, M.

    1996-12-31

    Due to the increasing attention paid on environmental protection, by the European Community, the Member States and the consumers, undertakings are forced to adjust their policies to meet the new demands posed by public authorities and the market. This has an inevitable impact on competition. No matter how acceptable the goals were, the means are to be assessed also from the competition law point of view. The objective of this study is to analyze the situations where conflicts may take place, the main sources of research being the principles of law relating to the Treaty ,the judgements of the European Court of Justice, the Commission Decisions and other official documents of the Community as well as legal literature. This study classifies the Community and Member State instruments which are used for environmental protection into four categories. These are legislative, market-based, horizontal and financial supporting instruments. Undertakings` environmental practices, which are capable of affecting competition, are examined under Articles 85 and 86 EC, some attention being paid also to Article 90 EC. The touching points of competition policy and environmental protection in such cases are scrutinized under three headings. These are the two, in this case, most relevant public instruments, ie. legislative and market-based measures, and the voluntary actions of undertakings. (42 refs.)

  10. 77 FR 59702 - Promoting U.S. EC Regulatory Compatibility

    Science.gov (United States)

    2012-09-28

    ... Promoting U.S. EC Regulatory Compatibility AGENCY: Office of the United States Trade Representative. ACTION... greater transatlantic regulatory compatibility generally. Concrete ideas on how greater compatibility... and EC invite your views on how to promote greater transatlantic regulatory compatibility...

  11. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to L-theanine from Camellia sinensis (L.) Kuntze (tea) and improvement of cognitive function (ID 1104, 1222, 1600, 1601, 1707, 1935, 2004, 2005), alleviation, of psychological stress (ID 1598, 1601), maintenance of normal sleep (ID 1222, 1737, 2004) and reduction of menstrual discomfort (ID 1599) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... claims in relation to L-theanine from Camellia sinensis (L.) Kuntze (tea) and improvement of cognitive function, alleviation of psychological stress, maintenance of normal sleep and reduction of menstrual discomfort. The scientific substantiation is based on the information provided by the Member States...

  12. News from the CERN Council

    CERN Multimedia

    The CERN Council today thanked the Organization’s outgoing management, and welcomed in the new. Outgoing Director General Robert Aymar, looked back on his five years at the helm, while new Director General, Rolf Heuer, presented his vision for the future. In other Council business, Romania was welcomed as a Candidate for Accession as Member State of CERN; and the groundwork was laid for a study of geographical and scientific extension of the role of CERN. Council also established the practical procedures for following projects relevant to the European Strategy for Particle Physics. Consult the complete Press Release.

  13. Summary of ECE Presentations at EC-18

    Directory of Open Access Journals (Sweden)

    Taylor G.

    2015-01-01

    Full Text Available There were nine ECE and one EBE presentation at EC-18. Four of the presentations were on various aspects of ECE on ITER. The ITER ECE diagnostic has entered an important detailed preliminary design phase and faces several design challenges in the next 2-3 years. Most of the other ECE presentations at the workshop were focused on applications of ECE diagnostics to plasma measurements, rather than improvements in technology, although it was apparent that heterodyne receiver technology continues to improve. CECE, ECE imaging and EBE imaging are increasingly providing valuable insights into plasma behavior that is important to understand if future burning plasma devices, such as ITER, FNSF and DEMO, are to be successful.

  14. Hewitt launches Research Councils UK

    CERN Multimedia

    2002-01-01

    "Trade and Industry Secretary Patricia Hewitt today launched 'Research Councils UK' - a new strategic partnership that will champion research in science, engineering and technology across the UK" (1 page).

  15. Scientific Opinion on the substantiation of a health claim related to an equimolar mixture of the CLA isomers c9,t11 and t10,c12 (marketed as Clarinol® and Tonalin® and ?contributes to a reduction in body fat mass? pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2015-01-01

    Full Text Available Following an application from BASF SE and Stepan Lipid Nutrition, submitted for the authorisation of a health claim pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of the Netherlands, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to an equimolar mixture (marketed under the trade names Clarinol® and Tonalin® of the two conjugated linoleic acid (CLA isomers c9,t11 and t10,c12. The Panel considers that the food is sufficiently characterised. The claimed effect is “contributes to a reduction in body fat mass”. In previous assessments on the safety of these equimolar isomeric mixtures of CLA, the NDA Panel considered that the observed increase in plasma and urinary concentrations of isoprostanes, which may indicate an increase in lipid peroxidation, and the increase in some markers of subclinical inflammation associated with CLA consumption, together with the limited data available on the effects of CLA on vascular function, may indicate a potential for vascular damage in the longer term. The Panel considers that the information provided does not establish that a reduction in body fat mass, when accompanied by an increase in markers of lipid peroxidation and inflammation, is a beneficial physiological effect for the target population. The Panel concludes that a cause and effect relationship has not been established between the consumption of an equimolar mixture of the CLA isomers c9,t11 and t10,c12, marketed under the trade names of Clarinol® and Tonalin®, and a beneficial physiological effect.

  16. Scientific Opinion on the substantiation of a health claim related to a combination of Bifidobacterium longum LA 101, Lactobacillus helveticus LA 102, Lactococcus lactis LA 103 and Streptococcus thermophilus LA 104 and reducing intestinal discomfort pursuant to Article 13(5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2014-05-01

    Full Text Available Following an application from PiLeJe, submitted pursuant to Article 13(5 of Regulation (EC No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to a combination of Bifidobacterium longum LA 101, Lactobacillus helveticus LA 102, Lactococcus lactis LA 103 and Streptococcus thermophilus LA 104 and reducing intestinal discomfort. The food that is the subject of the health claim is a combination of four bacterial strains—B. longum LA 101, L. helveticus LA 102, L. lactis LA 103 and S. thermophilus LA 104. The Panel considers that the food, a combination of B. longum LA 101, L. helveticus LA 102, L. lactis LA 103 and S. thermophilus LA 104, which is the subject of the health claim is sufficiently characterised. The claimed effect proposed by the applicant is "improves intestinal comfort". The Panel considers that reduction of gastro-intestinal discomfort is a beneficial physiological effect. The Panel considers that the only human study provided for the substantiation of the claim (with limitations did not find an effect of a combination of the bacterial strains being the subject of the claim on gastrointestinal discomfort. The Panel concludes that a cause and effect relationship has not been established between the consumption of a combination of B. longum LA 101, L. helveticus LA 102, L. lactis LA 103 and S. thermophilus LA 104 and reducing gastro-intestinal discomfort.

  17. Use of EC-blowers contribute to green investment; Gebruik van EC-ventilatoren levert bijdrage aan groene investering

    Energy Technology Data Exchange (ETDEWEB)

    Huijgens, G.; Ridder, A.

    2009-07-01

    Despite their small share in the entire use, applying EC blowers (electronically commutated) in coolers and condensers can provide an interesting contribution to a sound green investment. This additional investment with EC blowers will pay off through more efficient energy use and easy operation with rpm control. [Dutch] Door gebruik te maken van EC-ventilatoren (EC staat voor 'electronically commutated') op koelers en condensors kan, ondanks het kleine aandeel in het totaalverbruik, toch een interessante bijdrage geleverd worden aan een verantwoorde groene investering. Deze meerinvestering met EC-ventilatoren betaalt zich uit in zuinig energieverbruik en eenvoudige aansturing met toerenregeling.

  18. 75 FR 4493 - Natural Resources Defense Council; Denial of Petition for Rulemaking

    Science.gov (United States)

    2010-01-28

    ...; ] NUCLEAR REGULATORY COMMISSION 10 CFR Part 50 Natural Resources Defense Council; Denial of Petition for... Nuclear Regulatory Commission (NRC) is denying a petition for rulemaking submitted by the Natural Resources Defense Council (PRM- 50-90). The petitioner requested that the NRC amend the regulations...

  19. 75 FR 59143 - Magnuson-Stevens Fishery Conservation and Management Act; Regional Fishery Management Councils...

    Science.gov (United States)

    2010-09-27

    ... grant administration. NMFS understands the need for some flexibility to allow a Council to make minor... interaction with NMFS regarding Council administration, budget, and planning. The regulations do highlight the... National Oceanic and Atmospheric Administration 50 CFR Part 600 RIN 0648-AW18 Magnuson-Stevens...

  20. 78 FR 56706 - Depository Library Council to the Public Printer; Meeting

    Science.gov (United States)

    2013-09-13

    ... Depository Library Council to the Public Printer; Meeting The Depository Library Council to the Public... discuss the Federal Depository Library Program. All sessions are open to the public. The United States... Disabilities Act and meets all Fire Safety Act regulations. Davita Vance-Cooks, Public Printer of the...

  1. 76 FR 13617 - Depository Library Council to the Public Printer Meeting

    Science.gov (United States)

    2011-03-14

    ... Depository Library Council to the Public Printer Meeting The Depository Library Council to the Public Printer... Depository Library Program. All sessions are open to the public. The sleeping rooms available at the Crowne... Safety Act regulations. William J. Boarman, Public Printer of the United States. BILLING CODE 1520-01-P...

  2. 77 FR 27029 - The Manufacturing Council: Teleconference Meeting of the Manufacturing Council

    Science.gov (United States)

    2012-05-08

    ... International Trade Administration The Manufacturing Council: Teleconference Meeting of the Manufacturing... Manufacturing Council (Council). The agenda may change to accommodate Council business. The final agenda will be... Manufacturing Council, Room 4043, 1401 Constitution Avenue NW., Washington, DC 20230, telephone 202-482-4501...

  3. Watershed councils: it takes a community to restore a watershed

    Science.gov (United States)

    Marie Oliver; Rebecca Flitcroft

    2011-01-01

    Regulation alone cannot solve complex ecological problems on private lands that are managed for diverse uses. Executing coordinated restoration projects at the watershed scale is only possible with the cooperation and commitment of all stakeholders. Locally organized, nonregulatory watershed councils have proven to be a powerful method of engaging citizens from all...

  4. Real-time multi-EC-actuator MHD control on TCV

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, T. P.; Canal, G.; Duval, B. P.; Graves, J. P.; Kim, D.; Reimerdes, H.; Sauter, O.; Testa, D. [Ecole Polytechnique Fédérale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, CH-1015 Lausanne (Switzerland); Felici, F. [Ecole Polytechnique Fédérale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, CH-1015 Lausanne, Switzerland and Eindhoven University of Technology - Faculty of Mec (Netherlands); Collaboration: TCV Team

    2014-02-12

    Real-time control of multiple plasma actuators is a requirement in advanced tokamaks; for example for burn control, plasma current profile control and MHD stabilization - EC wave absorption is ideally suited especially for the latter. For example, on ITER 24 EC sources can be switched between 54 inputs at the torus. In the torus, 5 launchers direct the power to various locations across the plasma profile via 11 steerable mirrors. For optimal usage of the available power, the aiming and polarization of the beams must be adapted to the plasma configuration and the needs of the scenario. Since the EC system performs many competing tasks, present day systems should demonstrate the ability of an EC plant to deal with several targets in parallel and/or to switch smoothly between goals to attain overall satisfaction. Recently TCV has taken a first step towards such a demonstration. Several EC launchers are used simultaneously to regulate the sawtooth period and to preempt m/n = 3/2 NTMs, by controlling the power levels. In parallel, a second algorithm stabilizes any NTM that saturates [1]. These and real-time MHD control experiments on ELMs [2] are presented.

  5. Single-Particle Composition Measured in an Alpine Valley: Wood Smoke, EC and BC

    Science.gov (United States)

    Liepmann, C.; Gross, D. S.; Benzaid, S.; Christensen, J.; Turetsky, E.; Musicant, D.; Sandradewi, J.; Prevot, A.; Baltensperger, U.

    2007-12-01

    Particulate pollution is an issue of concern in today's society. Current regulations focus on the mass of particulate matter (PM) per volume of air, and not the source or chemical composition of the PM. Here we will present results from the AEROWOOD campaign in Roveredo, Switzerland where we investigated the PM composition measured using a single-particle mass spectrometer (TSI 3800 ATOFMS) to identify the sources of ambient particles. The goal was to differentiate wood smoke particles from diesel emissions. Roveredo is located in a deep alpine valley with strong wintertime thermal inversions, trapping the emissions. Local homes are predominantly heated by wood fires, and the village is located along a motorway that crosses the Swiss alps, providing two distinct particle sources. The particles sampled with the ATOFMS have been analyzed in a variety of ways with a focus on the temporal trends of the different particle types identified. Of particular interest is the distinction made between elemental carbon (EC) and black carbon (BC). During AEROWOOD, EC was measured chemically using real- time thermo/optical methods. BC was recorded directly by absorption, using an aethalometer. Regression models have been constructed to predict the EC and BC values using the single-particle mass spectra, providing chemical insight into the differences in these quantities. Additionally, comparing the timeline plots of EC, BC and the particle types found from the ATOFMS data should provide an idea as to the sources of EC and BC in this location.

  6. Determination of the role of noradrenergic and 5-hydroxytryptaminergic neurones in postsynaptic alpha 2-adrenoceptor desensitization by desipramine and ECS.

    OpenAIRE

    Heal, D. J.; Prow, M. R.; Buckett, W R

    1991-01-01

    1. Experiments were conducted to determine the respective roles which noradrenergic and 5-hydroxytryptaminergic neurones play in the down-regulation of postsynaptic alpha 2-adrenoceptors by desipramine and electroconvulsive shock (ECS). The functional status of these receptors was monitored by use of clonidine-induced mydriasis in conscious mice. 2. Mydriasis to clonidine (0.1 mg kg-1, i.p.) was markedly attenuated by administration of either desipramine (10 mg kg-1, i.p.) for 14 days or ECS ...

  7. Guidelines for accurate EC50/IC50 estimation.

    Science.gov (United States)

    Sebaugh, J L

    2011-01-01

    This article provides minimum requirements for having confidence in the accuracy of EC50/IC50 estimates. Two definitions of EC50/IC50s are considered: relative and absolute. The relative EC50/IC50 is the parameter c in the 4-parameter logistic model and is the concentration corresponding to a response midway between the estimates of the lower and upper plateaus. The absolute EC50/IC50 is the response corresponding to the 50% control (the mean of the 0% and 100% assay controls). The guidelines first describe how to decide whether to use the relative EC50/IC50 or the absolute EC50/IC50. Assays for which there is no stable 100% control must use the relative EC50/IC50. Assays having a stable 100% control but for which there may be more than 5% error in the estimate of the 50% control mean should use the relative EC50/IC50. Assays that can be demonstrated to produce an accurate and stable 100% control and less than 5% error in the estimate of the 50% control mean may gain efficiency as well as accuracy by using the absolute EC50/IC50. Next, the guidelines provide rules for deciding when the EC50/IC50 estimates are reportable. The relative EC50/IC50 should only be used if there are at least two assay concentrations beyond the lower and upper bend points. The absolute EC50/IC50 should only be used if there are at least two assay concentrations whose predicted response is less than 50% and two whose predicted response is greater than 50%. A wide range of typical assay conditions are considered in the development of the guidelines.

  8. 2011 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2011-01-01

    Vote Elections to fill all seats in the Staff Council are being organized this month. Voting will begin on Monday 31 October. Make your voice heard and be many to elect the new Staff Council. By doing so, you will be encouraging the men and women who will  represent you over the next two years and they will doubtless appreciate your gratitude. More details on the elections can be found on the Staff Association web site. (http://association.web.cern.ch) Elections Timetable Monday 31 October, at noon start date for voting Monday 14 November, at noon closing date for voting Monday 21 November, publication of the results in Echo Tuesday 22 and Wednesday 29 November Staff Association Assizes Tuesday 6 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure is monitored by the Election Committee. 

  9. EC Project 'GUIDELINES ON MPE': proposed qualification and curriculum frameworks and the MPE in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Caruana, C J, E-mail: carmel.j.caruana@um.edu.mt [EFOMP Representative on the EC ' Guidelines on MPE' Project and Biomedical Physics, Faculty of Health Sciences, University of Malta (Malta)

    2011-09-23

    The objectives of EC project 'Guidelines on Medical Physics Expert' are to provide for improved implementation of the provisions relating to the Medical Physics Expert within Council Directive 97/43/EURATOM and the proposed recast Basic Safety Standards directive. This includes harmonisation of the mission statement for Medical Physics Services as well as the education and training of the MPE. It also includes detailed knowledge-skills-competence inventories for the Medical Physics Expert in each of Diagnostic and Interventional Radiology, Nuclear Medicine and Radiotherapy. This paper presents the proposed Qualification and Curriculum Frameworks and their application to the Medical Physics Expert in Nuclear Medicine.

  10. Members of the State Council of Geneva

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Luncheon hosted by the Director-General for members of the State Council of Geneva: From left to right A. Naudi; J. May; M. Carlo Lamprecht, State Council - Employement, Foreign Office and Economic Departement; M. Robert Hensler, State Chancellor; L. Maiani, CERN Director General; H.F. Hoffmann; M. Robert Cramer, State Council - Environment, Agriculture and Interior Departement; J.Van Der Boon; M. Laurent Moutinot, State Council - Installation, equipment and housing Departement; C. Détraz; C. Wyss; P. Jenni; G. Hentsch; M. Pierre-François Unger, State Council - Health and Social Action Departement; G. Stassinakis; M. Bourquin, CERN Council President.

  11. EC Hidraulic Drive Cylinder Relief Vlave Test

    Energy Technology Data Exchange (ETDEWEB)

    Wu, J.; /Fermilab

    1991-04-03

    This engineering note documents the testing of the set pressure of the EC hydraulic drive cylinder relief valve. The purpose of the relief valve is to provide a safety measure in the event that oil becomes trapped in the rod side of the cylinder and pressure is applied to the cap side. The note includes an explanation of the procedure used and a summary of the result of the testing done on February 14, 1991 by Gary Trotter. The result was that the cylinder relief valve relieved at the correct set pressure of 10,500 psig. The basic concern is for the protection of the cylinder. The pump is capable of providing up to 10,500 psi of pressure to either side of the cylinder. The cylinder is rated for 10,500 psi. Under normal operating conditions, the valves would be open, and the pumping pressure would automatically flow oil into one side, and remove oil from the other side. If, however, the valve for the other side was closed, so that oil could not be removed, then the pressure would build in that side. If the rod side is pressurized to the maximum pump pressure of 10,500 psi, the cross sectional area ratio of 2.29 results in a pressure of approximately 4600 psi in the cap side, which is well under the rated pressure. If, however, the cap side is pressurized to 10,500 psi, the cross sectional area would produce a pressure of approximately 24,000 psi in the rod side, which could damage the cylinder. Therefore, the pressure on the rod side must be limited to the rated pressure of 10,500 psi. In reality, the maximum operating force on the piston would be under 11,000 Ibs., which would result in the maximum cylinder pressure being under 8000 psi to the rod side, and under 3500 psi to the cap side. Therefore, the relief is only needed as a safety precaution in the case that oil becomes trapped.

  12. REQUIREMENTS ECO-DESIGN VACUUMS BY COMMISSION REGULATION (EU NO 666/2013

    Directory of Open Access Journals (Sweden)

    Przemysław Kurczewski

    2014-10-01

    Full Text Available For several years, the executive acts related to the Directive of the European Parliament and of the Council 2009/125/EC of 21 October 2009 establishing a framework for the setting of ecodesign requirements for energy-related products are systematically adopted as a part of European Union legislation. Especially the Regulation 666/2013 concerning the eco-design requirements for vacuum cleaners introduced in July 2013 is strongly discussed. This article presents the background to the Directive 2009/125/EC and explains the concept that underlies the formulation of ecodesign requirements for different powered energy products, with special focus on the role of environmental life cycle assessment (LCA.

  13. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to polydextrose and changes in bowel function (ID 784), changes in short chain fatty acid (SCFA) production and/or pH in the gastro-intestinal tract (ID 784), decreasing, potentially pathogenic gastro-intestinal microorganisms (ID 785) and reduction of gastro-intestinal discomfort (ID 784) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to polydextrose and changes in bowel function, changes in short chain fatty acid (SCFA) production and/or pH in the gastro-intestinal tract, decreasing potentially pathogenic gastro-intestinal microorganisms and reduction of gastro-intestinal discomfort. The scientific substantiation......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food constituent that is the subject of the health claims is polydextrose. The Panel considers...

  14. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to n-3 polyunsaturated fatty acids (n-3 PUFAs) and “nutrient tasks and interactions” (ID 574), increase in calcium absorption leading to an increase in calcium retention, (ID 606), and maintenance of normal bone (ID 607) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food constituent that is the subject of the health claims is n-3 polyunsaturated fatty acids (n-3 PUFAs). The Panel considers that n-3 PUFAs are sufficiently characterised....... claims in relation to n-3 polyunsaturated fatty acids (n-3 PUFAs) and “nutrient tasks and interactions”, increase in calcium absorption leading to an increase in calcium retention, and maintenance of normal bone. The scientific substantiation is based on the information provided by the Member States......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...

  15. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion Part II on the substantiation of health claims related to various food(s)/food constituent(s) not supported by pertinent human data (ID 406, 462, 472, 543, 659, 678, 696, 858, 1381, 1403, 1437, 1438, 1513, 1536, 1537, , 1538, 1539, 1540, 1543, 1613, 1627, 1855, 1860, 1981, 2126, 2514, 3127, 4038, 4501, 4672, 4712, 4718) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to various food(s)/food constituent(s) not supported by pertinent human data. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... evaluated in this opinion. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of the food(s)/food constituent(s) and the claimed effects evaluated in this opinion....

  16. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion Part III on the substantiation of health claims related to various food(s)/food constituent(s) not supported by pertinent human data (ID 644, 946, 1717, 1730, 1742, 1760, 1871, 1894, 1910, 1926, 1933, 2000, 2024, , 2028, 2095, 2124, 2127, 2137, 2213, 2332, 2337, 2380, 2435, 2833, 2917, 3072, 3075, 3080, 3129, 3193, 3636, 4037, 4044, 4313) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to various food(s)/food constituent(s) not supported by pertinent human data. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... evaluated in this opinion. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of the food(s)/food constituent(s) and the claimed effects evaluated in this opinion....

  17. EFSA ND A Panel ( EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on the substantiation of a health claim related to eicosapentanoic acid (EPA) and “ reduces the AA/EPA ratio in blood. A high AA/EPA level is a risk factor in the d evelopment of attention difficulties in children with ADHD - like symptoms ” pursuant to Article 14 of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    of a health claim related to eicosapentaenoic acid (EPA) and “reduces the AA/EPA ratio in blood. A high AA/EPA level is a risk factor in the development of attention difficulties in children with attention deficit hyperactivity disorder (ADHD)-like symptoms”. The food constituent, EPA, which is the subject...... population (i.e. children with ADHD). The Panel concludes that the claimed effect relates to the treatment of a disease, and that therefore the health claim does not comply with the criteria laid down in Regulation (EC) No 1924/2006. © European Food Safety Authority, 2013...... of the health claim, is sufficiently characterised. The claimed effect proposed by the applicant is “reduces the AA/EPA ratio in blood. A high AA/EPA level is a risk factor in the development of attention difficulties in children with ADHD-like symptoms. These children are also characterised by less...

  18. (ID 1688), contribution to normal muscle function (ID 1685), and “immune system” (ID 1689, 1919, 1980) pursuant to Article 13(1) of Regulation (EC) No 1924/2006, EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to astaxanthin and protection of the skin from UV-induced damage (ID 1687, 1979), defence against Helicobacter pylori (ID 1686), contribution to normal spermatogenesis

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to astaxanthin and protection of the skin from UV-induced damage, defence against Helicobacter pylori, contribution to normal spermatogenesis, contribution to normal muscle function, and “immune system”. The scientific substantiation is based on the information provided by the Member......Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health...... States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food constituent that is the subject of the health claims is astaxanthin. The Panel considers that astaxanthin is sufficiently characterised....

  19. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on the substantiation of a health claim related to a combination of red spinach, green spinach, red chicory, green chicory, green leaf chard, red leaf chard, red Swiss chard, golden Swiss chard, and white Swiss chard and protection of blood lipids from oxidative damage pursuant to Article 13(5) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following an application from Italsur s.r.l., submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim...... related to a combination of red spinach, green spinach, red chicory, green chicory, green leaf chard, red leaf chard, red Swiss chard, golden Swiss chard and white Swiss chard and protection of blood lipids from oxidative damage. The food that is the subject of the health claim, a combination....... cicla), golden Swiss chard (Beta vulgaris L. var. cicla) and white Swiss chard (Beta vulgaris L. var. cicla), is sufficiently characterised. The claimed effect, protection of blood lipids from oxidative damage, may be a beneficial physiological effect. No human intervention studies from which...

  20. Analyzing 5 years of EC-TEL proceedings

    NARCIS (Netherlands)

    Reinhardt, Wolfgang; Meier, Christian; Drachsler, Hendrik; Sloep, Peter

    2011-01-01

    Reinhardt, W., Meier, C., Drachsler, H., & Sloep, P. B. (2011). Analyzing 5 years of EC-TEL proceedings. In C. D. Kloos, D. Gillet, R. M. Crespo García, F. Wild, & M. Wolpers (Eds.), Towards Ubiquitous Learning: 6th European Conference of Technology Enhanced Learning, EC-TEL 2011 (pp. 531-536). Sept

  1. A busy week for Council

    CERN Multimedia

    2009-01-01

    This has been a busy week for the CERN Council, and there is much to report. Firstly, I’m pleased to say that Council approved the Organization’s Medium Term Plan, and with it the budget for financial year 2010. In a time of global recession, this is a strong vote of confidence from the Member States. This meeting of Council provided an opportunity for the working group on the scientific and geographical enlargement of CERN to set out a roadmap towards its final report, which is to be made at Council’s December session this year. One part of the process over the coming months is to bring the major players in particle physics from beyond the European region into the discussion, ensuring that the working group’s recommendations lead to an optimum position for CERN and European particle physics in the global context. An indicator of the continuing attractiveness of CERN is the fact that Council has received four new applications...

  2. News from Council - September 2016

    CERN Multimedia

    2016-01-01

    I would like to inform you of the main news from the Council this week. First of all, the Council congratulated CERN and the Collaborations on the superb performance of the accelerator complex and experiments. It has been a great year so far, with important physics results across the whole spectrum of the CERN research programme.   Looking forward, one of the main accomplishments from this week’s meetings is that the Council has approved the opening of a credit facility with the European Investment Bank (EIB) to cover the cash shortage during the peak years of the High-Luminosity LHC (HL-LHC) construction. This is very good news since it will allow us to carry out the work necessary for the HL-LHC without compromising the rest of the Laboratory’s scientific programme. Turning to the scientific and geographical enlargement, the Council approved the admission of India as an Associate Member State, and I very much hope that the agreement can be signed in the near future so that Indi...

  3. Early insulin therapy Coordination Council

    Directory of Open Access Journals (Sweden)

    Marina Vladimirovna Shestakova

    2012-12-01

    Full Text Available Coordination Council has denoted the importance of adherence to Russian and international guidelines and prominent role of insulin therapy in management of type 2 diabetes mellitus (T2DM. Insulin therapy in T2DM preserves endogenous insulin secretion, prevents or decelerates development of microvascular complications and is known to be the most effective glucose-lowering treatment.

  4. Council celebrates CERN Control Centre

    CERN Multimedia

    2006-01-01

    With the unveiling of its new sign, the CERN Control Centre was officially inaugurated on Thursday 16 March. To celebrate its startup, CERN Council members visited the sleek centre, a futuristic-looking room filled with a multitude of monitoring screens.

  5. President's Council on Fitness, Sports and Nutrition

    Science.gov (United States)

    ... Newsletter Search Site President's Council on Fitness, Sports & Nutrition Be Active Why Is It Important? Ways To ... Jaci L. Van Heest, PhD. November 03, 2016 Nutrition Celebrate a Haunt-Healthy Halloween! By President's Council ...

  6. 76 FR 34230 - Technological Advisory Council

    Science.gov (United States)

    2011-06-13

    ... persons that the Federal Communications Commission's (FCC) Technological Advisory Council will hold a... Johnston, Chief, Electromagnetic Compatibility Division, Office of Engineering and Technology 202-418-0807; Walter.Johnston@FCC.gov . SUPPLEMENTARY INFORMATION: Technical Advisory Council members have...

  7. Report on Scottish council elections 2012

    OpenAIRE

    Bochel, Hugh; Denver, David; Steven, Martin

    2012-01-01

    This report to the Electoral Commission covers the Scottish council elections of May 2012. It considers aspects of the administration of the elections, turnout, patterns of candidature and party support and control of councils.

  8. 76 FR 64111 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2011-10-17

    ... SPACE ADMINISTRATION NASA Advisory Council; Meeting AGENCY: National Aeronautics and Space Administration. ACTION: Notice of meeting. SUMMARY: In accordance with the Federal Advisory Committee Act, Public... Advisory Council Administrative Officer, National Aeronautics and Space Administration, Washington,...

  9. President's Council on Fitness, Sports and Nutrition

    Science.gov (United States)

    ... A Print Share President's Council on Fitness, Sports & Nutrition (PCFSN) Fitness Homepage Intro Tile PCFSN engages, educates, ... lifestyle that includes regular physical activity and good nutrition. Since 1956, the Council has created and promoted ...

  10. All-College Council at Maryville College.

    Science.gov (United States)

    Blair, Carolyn L.

    In May 1968, the Special Committee on Community Life and Structure of Maryville College recommended that an All-College Council be organized by January 1969. Following approval of this recommendation by the Executive Council of the Faculty, the Special Committee proposed the nomination of 15 council members who were subsequently chosen in a…

  11. 77 FR 42297 - National Petroleum Council

    Science.gov (United States)

    2012-07-18

    ... National Petroleum Council AGENCY: Department of Energy, Office of Fossil Energy. ACTION: Notice of open meeting. ] SUMMARY: This notice announces a meeting of the National Petroleum Council. The Federal... Brought Before the National Petroleum Council Adjournment Public Participation: The meeting is open to the...

  12. 78 FR 40131 - National Petroleum Council

    Science.gov (United States)

    2013-07-03

    ... National Petroleum Council AGENCY: Office of Fossil Energy, Department of Energy. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the National Petroleum Council. The Federal Advisory... Business Properly Brought Before the National Petroleum Council Adjournment Public Participation: The...

  13. 76 FR 53889 - National Petroleum Council

    Science.gov (United States)

    2011-08-30

    ... National Petroleum Council AGENCY: Department of Energy, Office of Fossil Energy. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the National Petroleum Council. The Federal Advisory... National, Petroleum Council, Adjournment. Public Participation: The meeting is open to the public. The...

  14. The British Council's Global Cataloguing Service.

    Science.gov (United States)

    Magalhaes, Rodrigo; Nogueira, Madalena Sa

    1985-01-01

    The British Council Global Cataloging Service was initiated in 1980 to reduce duplication of cataloging same titles in council libraries abroad. Each of 56 council libraries participating in system receives list of new accessions and updated microfiche catalog. Portugal was one of the first six countries chosen to test the system. (EJS)

  15. Works Council Effectiveness: Determinants and Outcomes

    NARCIS (Netherlands)

    Sapulete, S.

    2013-01-01

    This thesis aimed to gain more insights into works council effectiveness in two ways: 1. studying the influence of works council presence on organizational outcomes; and, 2. studying the determinants of works council effectiveness. We found that productivity increases with the presence of a works co

  16. 76 FR 79655 - Manufacturing Council Meeting

    Science.gov (United States)

    2011-12-22

    ... International Trade Administration Manufacturing Council Meeting AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open meeting. SUMMARY: The Manufacturing Council will hold a..., trade agreements and other issues affecting the U.S. manufacturing sector and to determine the Council's...

  17. 77 FR 778 - Council Coordination Committee Meeting

    Science.gov (United States)

    2012-01-06

    ... National Oceanic and Atmospheric Administration RIN 0648-XA918 Council Coordination Committee Meeting...), Commerce. ACTION: Notice of a public meeting. SUMMARY: NMFS will host a meeting of the Council Coordination... Reauthorization Act (MSRA) of 2006 established the Council Coordination Committee by amending Section 302 (16...

  18. 75 FR 31418 - Intermountain Region, Payette National Forest, Council Ranger District; Idaho; Mill Creek-Council...

    Science.gov (United States)

    2010-06-03

    ... Forest Service Intermountain Region, Payette National Forest, Council Ranger District; Idaho; Mill Creek... Forest will prepare an environmental impact statement (EIS) for the Mill Creek--Council Mountain... Council, Idaho. The Mill Creek--Council Mountain Landscape Restoration Project proposes to...

  19. 77 FR 38317 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-06-27

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife..., announce a public teleconference of the Wildlife and Hunting Heritage Conservation Council (Council). DATES... that Wildlife and Hunting Heritage Conservation Council will hold a teleconference. Background...

  20. 76 FR 3155 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2011-01-19

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... that Wildlife and Hunting Heritage Conservation Council will hold a meeting. Background Formed...

  1. 78 FR 42104 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2013-07-15

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife..., announce a public teleconference of the Wildlife and Hunting Heritage Conservation Council (Council). DATES... Wildlife and Hunting Heritage Conservation Council will hold a teleconference. Background Formed...

  2. 77 FR 16051 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-03-19

    ... Office of the Secretary Wildlife and Hunting Heritage Conservation Council AGENCY: Office of the... Hunting Heritage Conservation Council (Council). The Council provides advice about wildlife and habitat conservation endeavors that (a) benefit wildlife resources; (b) encourage partnership among the...

  3. 77 FR 74864 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-12-18

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting.... App., we announce that Wildlife and Hunting Heritage Conservation Council will hold a...

  4. 77 FR 31636 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-05-29

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... Council provides advice about wildlife and habitat conservation endeavors that: 1. Benefit...

  5. 75 FR 57292 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2010-09-20

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... that Wildlife and Hunting Heritage Conservation Council will hold a meeting. Background Formed...

  6. 77 FR 15386 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-03-15

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife..., announce a public teleconference of the Wildlife and Hunting Heritage Conservation Council (Council). DATES... that Wildlife and Hunting Heritage Conservation Council will hold a teleconference. Background...

  7. 77 FR 27440 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-05-10

    ... National Oceanic and Atmospheric Administration New England Fishery Management Council; Public Meeting...), Commerce. ACTION: Notice; public meeting. SUMMARY: The New England Fishery Management Council (Council) is... INFORMATION CONTACT: Paul J. Howard, Executive Director, New England Fishery Management Council;...

  8. Proteomics-Based Metabolic Modeling Reveals That Fatty Acid Oxidation (FAO) Controls Endothelial Cell (EC) Permeability*

    Science.gov (United States)

    Patella, Francesca; Schug, Zachary T.; Persi, Erez; Neilson, Lisa J.; Erami, Zahra; Avanzato, Daniele; Maione, Federica; Hernandez-Fernaud, Juan R.; Mackay, Gillian; Zheng, Liang; Reid, Steven; Frezza, Christian; Giraudo, Enrico; Fiorio Pla, Alessandra; Anderson, Kurt; Ruppin, Eytan; Gottlieb, Eyal; Zanivan, Sara

    2015-01-01

    Endothelial cells (ECs) play a key role to maintain the functionality of blood vessels. Altered EC permeability causes severe impairment in vessel stability and is a hallmark of pathologies such as cancer and thrombosis. Integrating label-free quantitative proteomics data into genome-wide metabolic modeling, we built up a model that predicts the metabolic fluxes in ECs when cultured on a tridimensional matrix and organize into a vascular-like network. We discovered how fatty acid oxidation increases when ECs are assembled into a fully formed network that can be disrupted by inhibiting CPT1A, the fatty acid oxidation rate-limiting enzyme. Acute CPT1A inhibition reduces cellular ATP levels and oxygen consumption, which are restored by replenishing the tricarboxylic acid cycle. Remarkably, global phosphoproteomic changes measured upon acute CPT1A inhibition pinpointed altered calcium signaling. Indeed, CPT1A inhibition increases intracellular calcium oscillations. Finally, inhibiting CPT1A induces hyperpermeability in vitro and leakage of blood vessel in vivo, which were restored blocking calcium influx or replenishing the tricarboxylic acid cycle. Fatty acid oxidation emerges as central regulator of endothelial functions and blood vessel stability and druggable pathway to control pathological vascular permeability. PMID:25573745

  9. Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.

    Science.gov (United States)

    Patella, Francesca; Schug, Zachary T; Persi, Erez; Neilson, Lisa J; Erami, Zahra; Avanzato, Daniele; Maione, Federica; Hernandez-Fernaud, Juan R; Mackay, Gillian; Zheng, Liang; Reid, Steven; Frezza, Christian; Giraudo, Enrico; Fiorio Pla, Alessandra; Anderson, Kurt; Ruppin, Eytan; Gottlieb, Eyal; Zanivan, Sara

    2015-03-01

    Endothelial cells (ECs) play a key role to maintain the functionality of blood vessels. Altered EC permeability causes severe impairment in vessel stability and is a hallmark of pathologies such as cancer and thrombosis. Integrating label-free quantitative proteomics data into genome-wide metabolic modeling, we built up a model that predicts the metabolic fluxes in ECs when cultured on a tridimensional matrix and organize into a vascular-like network. We discovered how fatty acid oxidation increases when ECs are assembled into a fully formed network that can be disrupted by inhibiting CPT1A, the fatty acid oxidation rate-limiting enzyme. Acute CPT1A inhibition reduces cellular ATP levels and oxygen consumption, which are restored by replenishing the tricarboxylic acid cycle. Remarkably, global phosphoproteomic changes measured upon acute CPT1A inhibition pinpointed altered calcium signaling. Indeed, CPT1A inhibition increases intracellular calcium oscillations. Finally, inhibiting CPT1A induces hyperpermeability in vitro and leakage of blood vessel in vivo, which were restored blocking calcium influx or replenishing the tricarboxylic acid cycle. Fatty acid oxidation emerges as central regulator of endothelial functions and blood vessel stability and druggable pathway to control pathological vascular permeability.

  10. THE RESULT OF THE TRANSPOSITION OF EU DIRECTIVES INTO NATIONAL LEGISLATION. THE FIRST CASE AGAINST ROMANIA REGARDING THE IMPLEMENTATION OF THE RACIAL EQUALITY DIRECTIVE (2000/43/EC AND OF THE EQUAL TREATMENT DIRECTIVE (2000/78/EC

    Directory of Open Access Journals (Sweden)

    CRISTIAN JURA

    2011-04-01

    Full Text Available The purpose if this research paper is to analyze how the two directives, The Racial Equality Directive (2000/43/EC and of The Equal Treatment Directive (2000/78/EC, were transposed into national legislation. One objective of the paper is to present and analyze some outcomes of the transposition: the national legislation on combating discrimination and the national institutions in this field. The second objective is to present and analyze the first case against Romania regarding the transposition of The Racial Equality Directive (2000/43/EC and of The Equal Treatment Directive (2000/78/EC into national legislation: preliminary ruling C-310/10 (Agafi ei and Others, Romania and the possible impact of this case. Council Directive 2000/43 is implementing the principle of equal treatment between persons irrespective of racial or ethnic origin. Directive 2000/78/EC is establishing a general framework for equal treatment in employment and occupation. The case stems from a salary dispute Agafitei and others, staff of the national anti-corruption board and management research to fight organized crime and terrorism. There is a reward past circumstances arise system with two tracks: one that is followed by the 'attorneys' and by other staff. For the first track counts along the length of service for the second. Since there is no (additional qualification requirements for the group of prosecutors, according to defendants pay equal. In a national procedure Agafitei others (defendants in the national procedure in the right, and their employers to pay the lost wages. The respective employers, however, did not agree and make cassation.

  11. Resolution of the Staff Council

    CERN Document Server

    Staff Association

    2015-01-01

    You were many to attend the public information meetings organised in October and we thank you for your interest. In this decision phase of the current Five-Yearly Review of our employment conditions they provided an opportunity to review the Management proposals in detail. They were a moment of exchange also on the various topics under review, and your comments were many and very valuable. Meeting on Thursday 29th October, the Staff Council discussed once more these proposals. It considered that the "package" of proposed measures is not balanced enough in its current form. It decided to formulate additional requests to the Management, relating mainly to the effects of the introduction of the proposed new career system. The resolution adopted this morning also implies that the consultation of staff, originally foreseen next week, is postponed. The staff Council will reconvene in a special session on Thursday, 5th November to reassess its position depending on the progress made regarding its d...

  12. 2015 Elections to Staff Council

    CERN Document Server

    Staff Asscociation

    2015-01-01

    Make your voice heard, support your candidates! Be many to vote and to elect the new Staff Council. By doing so, you will be encouraging the men and women who will represent you over the next two years and they will without doubt appreciate your gratitude. The voting takes place from the 26th of October to the 9th of November, at noon at https://ap-vote.web.cern.ch/elections-2015.   Elections Timetable Monday 9 November, at noon Closing date for voting Monday 16 and Monday 23 November, publication of the results in Echo Tuesday 8 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure will be monitored by the Election Committee, which is also in charge of announcing the results in Echo on 16 and 24 November. Candidates for the 2015 elections

  13. The resistance councils in Uganda

    DEFF Research Database (Denmark)

    Tidemand, Per

    in the capitals. In my dissertation I propose to change that focus. Partly by paying particular attention to rural politics, partly through a discussion of democracy in a longer-term perspective using a broader definition of democracy and finally through a discussion of democracy as effective political...... participation rather than only form al rights. I shall do so by analysing the Resistance Councils (RCs) in Uganda....

  14. Temperature Control of Evaporative Cooler (EC for Converter Dry Dedusting

    Directory of Open Access Journals (Sweden)

    Li Fangwei

    2013-09-01

    Full Text Available The converter dry dedusting is more complicated with higher requirements in automatic control than the wet dust extraction. The key difficult point is the EC temperature control. This paper puts forth a method to effectively deal with the fluctuated-drastically temperature caused by control lagging at the EC outlet in the traditional converter dry dedusting. The EC outlet temperature can be under control of technological requirement by combining controls of proportion, empirical value, fuzziness and PID. The intelligent system is available with parameter auto tuning, which facilitates the on-site debugging greatly for operators. The result of the on-site application suggests that this method can be used to well handle some technological difficulties in the EC temperature control.    

  15. Electronic Project of Taxation Based on EC Under Single Nation

    Institute of Scientific and Technical Information of China (English)

    WANG Tao; ZENG Xiao-ping

    2002-01-01

    Because of no real location and its virtual interaction, the information flow, the cash flow and the logistic flow of EC(Electronic Commerce) are to be separated individually. So the traditional taxation based on those three flows is challenged. Under this condition, this paper researches how to levy taxes on EC through internet using internet technology. As to simplify the model, it relates under a single nation. But it will also give some measures about the international trades.

  16. Progress in conceptual design of EU DEMO EC system

    Science.gov (United States)

    Garavaglia, Saul; Bruschi, Alex; Franke, Thomas; Granucci, Gustavo; Grossetti, Giovanni; Jelonnek, John; Moro, Alessandro; Poli, Emanuele; Rispoli, Natale; Strauss, Dirk; Tran, Quang Minh

    2017-07-01

    Since 2014 under the umbrella of EUROfusion Consortium the Work Package Heating and Current Drive (WPHCD) is performing the engineering design and R&D for the electron cyclotron (EC), ion cyclotron and neutral beam systems of the future fusion power plant DEMO. This presentation covers the activities performed in the last two years on the EC system conceptual design, as part of the WPHCD, focusing on launchers, transmission lines, system reliability and architecture.

  17. Expression of a finger millet transcription factor, EcNAC1, in tobacco confers abiotic stress-tolerance.

    Directory of Open Access Journals (Sweden)

    Venkategowda Ramegowda

    Full Text Available NAC (NAM, ATAF1-2, and CUC2 proteins constitute one of the largest families of plant-specific transcription factors and have been shown to be involved in diverse plant processes including plant growth, development, and stress-tolerance. In this study, a stress-responsive NAC gene, EcNAC1, was isolated from the subtracted stress cDNA library generated from a drought adapted crop, finger millet, and characterized for its role in stress-tolerance. The expression analysis showed that EcNAC1 was highly induced during water-deficit and salt stress. EcNAC1 shares high amino acid similarity with rice genes that have been phylogenetically classified into stress-related NAC genes. Our results demonstrated that tobacco transgenic plants expressing EcNAC1 exhibit tolerance to various abiotic stresses like simulated osmotic stress, by polyethylene glycol (PEG and mannitol, and salinity stress. The transgenic plants also showed enhanced tolerance to methyl-viologen (MV induced oxidative stress. Reduced levels of reactive oxygen species (ROS and ROS-induced damage were noticed in pot grown transgenic lines under water-deficit and natural high light conditions. Root growth under stress and recovery growth after stress alleviation was more in transgenic plants. Many stress-responsive genes were found to be up-regulated in transgenic lines expressing EcNAC1. Our results suggest that EcNAC1 overexpression confers tolerance against abiotic stress in susceptible species, tobacco.

  18. Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties.

    Science.gov (United States)

    Tarrant, Ann M; Behrendt, Lars; Stegeman, John J; Verslycke, Tim

    2011-09-01

    In arthropods, ecdysteroids regulate molting by activating a heterodimer formed by the ecdysone receptor (EcR) and retinoid X receptor (RXR). While this mechanism is similar in insects and crustaceans, variation in receptor splicing, dimerization and ligand affinity adds specificity to molting processes. This study reports the EcR and RXR sequences from American lobster, a commercially and ecologically important crustacean. We cloned two EcR splice variants, both of which specifically bind ponasterone A, and two RXR variants, both of which enhance binding of ponasterone A to the EcR. Lobster EcR has high affinity for ponasterone A and muristerone and moderately high affinity for the insecticide tebufenozide. Bisphenol A, diethyl phthalate, and two polychlorinated biphenyls (PCB 29 and PCB 30), environmental chemicals shown to interfere with crustacean molting, showed little or no affinity for lobster EcR. These studies establish the molecular basis for investigation of lobster ecdysteroid signaling and signal disruption by environmental chemicals.

  19. Notification of upcoming AGU Council meeting

    Science.gov (United States)

    Williams, Billy

    2012-10-01

    The AGU Council will meet on Sunday, 2 December 2012, at the InterContinental Hotel in San Francisco, Calif. The meeting, which is open to all AGU members, will include discussions of AGU's new Grand Challenge Project (a project that will be introduced to members at the 2012 Fall Meeting), the proposed AGU scientific ethics policy, publishing strategies, future plans for honors and recognition, and leadership transition as new members join the Council. This year the Council experimented with a new approach to conducting business. By holding virtual meetings throughout the year, Council members have been able to act in a more timely manner and provide input on important membership and science issues on the Board of Directors' agenda. The Council Leadership Team—an elected subset of the Council—also experimented with a new approach, meeting every month to keep moving projects forward. This approach has increased communication and improved effectiveness in Council decision making.

  20. The effectiveness of the Arctic Council

    OpenAIRE

    2012-01-01

    Created in 1996, the Arctic Council has now been in operation long enough to justify a systematic effort to assess its effectiveness. To explore this topic, we created a questionnaire and circulated it to a large number of individuals who have participated in the work of the council in one capacity or another or who have followed the work of the council closely. This article analyses the quantitative and the qualitative input of those who responded to the questionnaire. The main conclusions a...

  1. 75 FR 14427 - Gulf of Mexico Fishery Management Council (Council); Public Meetings

    Science.gov (United States)

    2010-03-25

    ...., Galveston, TX 77551. Council address: Gulf of Mexico Fishery Management Council, 2203 North Lois Avenue... update on the SEFSC Methodology for Age Composition for Red Drum. Although other non-emergency issues...

  2. 78 FR 55114 - Native American Employment and Training Council (Council) Charter; Notice of Intent To Renew

    Science.gov (United States)

    2013-09-09

    ... Employment and Training Administration Native American Employment and Training Council (Council) Charter; Notice of Intent To Renew AGENCY: Employment and Training Administration, Labor. ACTION: Notice of Intent... Labor (the Department), Employment and Training Administration (ETA) intends to renew the...

  3. 2015 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2015-01-01

    Elections Timetable Monday 21 September, at noon Start date for receipt of the application Friday 16 October, at noon Closing date for receipt of the applications Monday 26 October, at noon Start date for voting Monday 9 November, at noon Closing date for voting Monday 16 and Monday 23 November, publication of the results in Echo Monday 23 and Tuesday 24 November Staff Association Assizes Tuesday 1st December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure will be monitored by the Election Committee, which is also in charge of announcing the results in Echo on 16 and 24 November. During its meeting of March 17 2015, the Staff Council approved the election rules, which define the allocation of seats in each department, as follows:   Number of seats in the electoral colleges Departments BE EN TE DG/DGS FP GS HR/PF IT PH Career paths AA - D 2 3 3 1 1 2 1 1 2 Career paths E - G 2 2 2 1 1 1 1 2 3   ...

  4. 2015 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2015-01-01

    Elections Timetable Monday 26 October, at noon Start date for voting Monday 9 November, at noon Closing date for voting Monday 16 and Monday 23 November, publication of the results in Echo Monday 23 and Tuesday 24 November Staff Association Assizes Tuesday 1st December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure will be monitored by the Election Committee, which is also in charge of announcing the results in Echo on 16 and 24 November. During its meeting of March 17 2015, the Staff Council approved the election rules, which define the allocation of seats in each department, as follows:   Number of seats in the electoral colleges Departments BE EN TE DG/DGS FP GS HR/PF IT PH Career paths AA - D 2 3 3 1 1 2 1 1 2 Career paths E - G 2 2 2 1 1 1 1 2 3   Global CERN Career paths AA - G 14     Number of seats for fellows representatives Global CERN 5 For more informat...

  5. Alpha- and EC-decay measurements of {sup 257}Rf

    Energy Technology Data Exchange (ETDEWEB)

    Hessberger, F.P. [GSI - Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Helmholtz Institut Mainz, Mainz (Germany); Antalic, S.; Andel, B.; Kalaninova, Z. [Comenius University in Bratislava, Department of Nuclear Physics and Biophysics, Bratislava (Slovakia); Mistry, A.K.; Laatiaoui, M. [Helmholtz Institut Mainz, Mainz (Germany); GSI - Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Ackermann, D.; Kindler, B.; Kojouharov, I.; Lommel, B. [GSI - Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Block, M. [GSI - Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Helmholtz Institut Mainz, Mainz (Germany); Johannes Gutenberg-Universitaet Mainz, Mainz (Germany); Piot, J.; Vostinar, M. [GANIL, Caen (France)

    2016-07-15

    Alpha- and Electron capture (EC) decay properties of {sup 257}Rf were investigated by measuring α-γ coincidences and correlations between conversion electrons (CE) emitted during the process of EC decay of {sup 257}Rf and α decays of the daughter isotope {sup 257}Lr. So far, previously unobserved α (8296 keV)-γ (557 keV) coincidences were measured and interpreted as decays of {sup 257m}Rf (11/2{sup -}[725]) into the 7/2{sup -}[743] level in {sup 253}No. A search of delayed coincidences between α particles and signals at E ≤ 1000 keV, which are interpreted as being due to CE emission, revealed a clear correlation between CE and α particles from the decay of {sup 257}Lr, which is regarded as a direct proof of the EC decay of {sup 257g}Rf and {sup 257m}Rf. (orig.)

  6. Regulatory aspects of pharmaceuticals' exports in gulf cooperation council countries.

    Science.gov (United States)

    Pateriya, S; Janodia, Md; Deshpande, Pb; Ligade, Vs; Talole, Kb; Kulshrestha, T; Kamariya, Y; Musmade, Pb; Udupa, N

    2011-04-01

    The Gulf cooperation council (GCC) region is considered as "Emerging market" for pharmaceutical export and bilateral trade. The understanding of the regulatory requirements of this region can be beneficial for pharmaceutical export. Some incidents of the year 2008-09, like recession or economic slowdown in highly well-off and regulated market of the EU and US, raised the demand for alternate destinations for business. The regulations of Gulf countries are encouraging the import of quality generic products, which can be good news to the Indian drug manufacturers.

  7. 78 FR 61840 - Pacific Fishery Management Council (Pacific Council); Public Meetings

    Science.gov (United States)

    2013-10-04

    ... Methodology Review Process and Preliminary Topic Selection 5. Pacific Sardine Stock Assessment and Management... 0648-XC914 Pacific Fishery Management Council (Pacific Council); Public Meetings AGENCY: National... Pacific Council will meet as late as necessary each day to complete its scheduled business. ADDRESSES...

  8. 75 FR 80039 - The Manufacturing Council: Meeting of the Manufacturing Council

    Science.gov (United States)

    2010-12-21

    ... International Trade Administration The Manufacturing Council: Meeting of the Manufacturing Council AGENCY... Manufacturing Council will hold a meeting to discuss competitiveness, clean energy, export/import issues and workforce development issues affecting the U.S. manufacturing sector and to receive briefings from the...

  9. 75 FR 60411 - The Manufacturing Council: Meeting of the Manufacturing Council

    Science.gov (United States)

    2010-09-30

    ... International Trade Administration The Manufacturing Council: Meeting of the Manufacturing Council AGENCY... Manufacturing Council will hold a meeting to discuss and identify the priority issues affecting the U.S. manufacturing industry, which may include increasing exports, supply chain and access to credit, among others...

  10. 76 FR 57714 - The Manufacturing Council: Meeting of the Manufacturing Council

    Science.gov (United States)

    2011-09-16

    ... International Trade Administration The Manufacturing Council: Meeting of the Manufacturing Council AGENCY... Manufacturing Council will hold a meeting to hear updates from the Department of Commerce in addition to the... agreements and other issues affecting the U.S. manufacturing sector and to determine future areas of focus...

  11. 77 FR 26743 - The Manufacturing Council: Work Session of the Manufacturing Council

    Science.gov (United States)

    2012-05-07

    ... International Trade Administration The Manufacturing Council: Work Session of the Manufacturing Council AGENCY...: This notice sets forth the schedule and agenda for an open work session of the Manufacturing Council... Freescale Austin Technology and Manufacturing Center, 3501 Ed Bluestein Boulevard, Austin, Texas. All guests...

  12. 75 FR 10216 - The Manufacturing Council: Meeting of the Manufacturing Council

    Science.gov (United States)

    2010-03-05

    ...: 2010-4797] DEPARTMENT OF COMMERCE International Trade Administration The Manufacturing Council: Meeting of the Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open meeting. SUMMARY: The Manufacturing Council will hold a meeting to discuss a...

  13. ECS: efficient communication scheduling for underwater sensor networks.

    Science.gov (United States)

    Hong, Lu; Hong, Feng; Guo, Zhongwen; Li, Zhengbao

    2011-01-01

    TDMA protocols have attracted a lot of attention for underwater acoustic sensor networks (UWSNs), because of the unique characteristics of acoustic signal propagation such as great energy consumption in transmission, long propagation delay and long communication range. Previous TDMA protocols all allocated transmission time to nodes based on discrete time slots. This paper proposes an efficient continuous time scheduling TDMA protocol (ECS) for UWSNs, including the continuous time based and sender oriented conflict analysis model, the transmission moment allocation algorithm and the distributed topology maintenance algorithm. Simulation results confirm that ECS improves network throughput by 20% on average, compared to existing MAC protocols.

  14. The Danish EC/EU referenda from 1972-2015

    OpenAIRE

    Poulsen, Kristian Ersbøll Berg; Sander, Rasmus Christian Wolff

    2016-01-01

    The main research question of this thesis is: “By which dominant discourses are truth value claimed in an electoral campaign prior to a Danish EC/EU referendum and how is this ‘a collective activity of thinking’?” To answer the research question, a Governmentality analysis of the Danish EC/EU referenda from 1972-2015 is conducted based on the theoretical framework of Michel Foucault, Nikolas Rose & Peter Miller and Mitchell Dean. Furthermore, four qualitative interviews with politicians an...

  15. ECS: Efficient Communication Scheduling for Underwater Sensor Networks

    Directory of Open Access Journals (Sweden)

    Lu Hong

    2011-03-01

    Full Text Available TDMA protocols have attracted a lot of attention for underwater acoustic sensor networks (UWSNs, because of the unique characteristics of acoustic signal propagation such as great energy consumption in transmission, long propagation delay and long communication range. Previous TDMA protocols all allocated transmission time to nodes based on discrete time slots. This paper proposes an efficient continuous time scheduling TDMA protocol (ECS for UWSNs, including the continuous time based and sender oriented conflict analysis model, the transmission moment allocation algorithm and the distributed topology maintenance algorithm. Simulation results confirm that ECS improves network throughput by 20% on average, compared to existing MAC protocols.

  16. Cloning and Expression Analysis of One Gamma-Glutamylcysteine Synthetase Gene (Hbγ-ECS1 in Latex Production in Hevea brasiliensis

    Directory of Open Access Journals (Sweden)

    Wei Fang

    2016-01-01

    Full Text Available Rubber tree is a major commercial source of natural rubber. Latex coagulation is delayed by thiols, which belong to the important type of antioxidants in laticifer submembrane, and is composed of glutathione (GSH, cysteine, and methionine. The rate-limiting enzyme, γ-ECS, plays an important role in regulating the biosynthesis of glutathione under any environment conditions. To understand the relation between γ-ECS and thiols and to correlate latex flow with one-time tapping and continuous tapping, we cloned and derived the full length of one γ-ECS from rubber tree latex (Hbγ-ECS1. According to qPCR analysis, the expression levels of Hbγ-ECS1 were induced by tapping and Ethrel stimulation, and the expression was related to thiols content in the latex. Continuous tapping induced injury, and the expression of HbγECS1 increased with routine tapping and Ethrel-stimulation tapping (more intensive tapping. According to expression in long-term flowing latex, the gene was related to the duration of latex flow. HbγECS1 was expressed in E. coli Rosetta using pET-sumo as an expression vector and the recombinant enzyme was purified; then we achieved 0.827 U/mg specific activity and about 66 kDa molecular weight. The present study can help us understand the complex role of Hbγ-ECS in thiols biosynthesis, which is influenced by tapping.

  17. 50 CFR 600.250 - Council member training.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Council Membership § 600.250 Council... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Council member training. 600.250 Section... to matters before the Councils and shall make the training course available to all Council...

  18. Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex.

    Directory of Open Access Journals (Sweden)

    Yoshitaka Sato

    2009-07-01

    Full Text Available p53-signaling is modulated by viruses to establish a host cellular environment advantageous for their propagation. The Epstein-Barr virus (EBV lytic program induces phosphorylation of p53, which prevents interaction with MDM2. Here, we show that induction of EBV lytic program leads to degradation of p53 via an ubiquitin-proteasome pathway independent of MDM2. The BZLF1 protein directly functions as an adaptor component of the ECS (Elongin B/C-Cul2/5-SOCS-box protein ubiquitin ligase complex targeting p53 for degradation. Intringuingly, C-terminal phosphorylation of p53 resulting from activated DNA damage response by viral lytic replication enhances its binding to BZLF1 protein. Purified BZLF1 protein-associated ECS could be shown to catalyze ubiquitination of phospho-mimetic p53 more efficiently than the wild-type in vitro. The compensation of p53 at middle and late stages of the lytic infection inhibits viral DNA replication and production during lytic infection, suggesting that the degradation of p53 is required for efficient viral propagation. Taken together, these findings demonstrate a role for the BZLF1 protein-associated ECS ligase complex in regulation of p53 phosphorylated by activated DNA damage signaling during viral lytic infection.

  19. Coordinating Council. Ninth Meeting: Total Quality Management

    Science.gov (United States)

    1992-01-01

    This report summarizes the 9th meeting of the STI Coordinating Council. The council listened to the speakers' understanding of Total Quality Management (TQM) principles and heard stories of successful applications of these principles. Definitions of quality stated were focused on customer satisfaction. Reports presented by the speakers are also included.

  20. Developing Self-Esteem through Student Council

    Science.gov (United States)

    Marriott, Mary Ann

    2004-01-01

    For a middle school student council to be effective, it must address the unique behaviors of and situations that arise for adolescents. The development of decision-making skills, conflict resolution skills, and cooperative learning and working not only provides a framework for success as a council, but also enables students to maximize their own…

  1. 77 FR 59026 - Federal Salary Council

    Science.gov (United States)

    2012-09-25

    ... the fields of labor relations and pay policy. The Council makes recommendations to the President's Pay... of pay, and the level of comparability payments that should be paid. The Council will hear public testimony about the locality pay program, review the results of pay comparisons, and formulate its...

  2. 78 FR 61404 - Federal Salary Council; Meeting

    Science.gov (United States)

    2013-10-03

    ... Council will hear public testimony about the locality pay program, review the results of pay comparisons... experts in the fields of labor relations and pay policy. The Council makes recommendations to the... rates, and locality pay areas and boundaries for 2015. The meeting is open to the public. Please contact...

  3. 76 FR 59175 - Federal Salary Council; Meeting

    Science.gov (United States)

    2011-09-23

    ... Council will hear public testimony about the locality pay program, review the results of pay comparisons... experts in the fields of labor relations and pay policy. The Council makes recommendations to the... rates, and locality pay areas and boundaries for 2013. The meeting is open to the public. Please contact...

  4. 78 FR 65717 - Federal Salary Council

    Science.gov (United States)

    2013-11-01

    ... the fields of labor relations and pay policy. The Council makes recommendations to the President's Pay... of pay, and the level of comparability payments that should be paid. The Council will hear public testimony about the locality pay program, review the results of pay comparisons, and formulate its...

  5. 76 FR 62133 - National Women's Business Council

    Science.gov (United States)

    2011-10-06

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business Administration. ACTION: Notice of... location, date, time, and agenda for the next meeting of the National Women's Business Council (NWBC)....

  6. 77 FR 61466 - National Women's Business Council

    Science.gov (United States)

    2012-10-09

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business Administration. ACTION: Notice of... location, date, time, and agenda for the next meeting of the National Women's Business Council (NWBC)....

  7. 78 FR 44187 - National Women's Business Council

    Science.gov (United States)

    2013-07-23

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Women's Business Council ACTION: Notice of open Federal advisory committee meeting... meeting of the National Women's Business Council (NWBC). The meeting will be open to the public. ]...

  8. Voices from CCPIT Sub-Councils

    Institute of Scientific and Technical Information of China (English)

    Yan Manman

    2010-01-01

    @@ All the branches and headquarters comprise the huge and crisscross network of CCPIT system.At the National CCPIT Work Meeting on January 16-17,2010,50 CCPIT local sub-councils,22 CCPIT industrial sub-councils,16CCPIT overseas offices voiced their views on how CCPIT can be built as a worldwide top class trade promotion agency.

  9. 78 FR 7424 - National Coal Council

    Science.gov (United States)

    2013-02-01

    ... Clean Coal Electricity 5. Jim Butz, Vice President of Product Management, Novinda Corp.: ``Mercury... National Coal Council AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Coal Council (NCC). The Federal Advisory Committee Act (Pub. L....

  10. Health council report 'Antimicrobial growth promoters'.

    NARCIS (Netherlands)

    Goettsch, W; Degener, JE

    1999-01-01

    The Health Council of the Netherlands has issued a report on the risk of development of resistance among bacteria as result of the use of antibiotics as growth promotors in livestock farming. The committee appointed by the Health Council conclude that the use of antimicrobial growth promotors contri

  11. The Agricultural Development Council. A History.

    Science.gov (United States)

    Stevenson, Russell; Locke, Virginia O.

    This history of the Agriculture Development Council (ADC) consists of eight chapters and four appendices. Chapter 1 traces the early years of the ADC, from its inception in 1953 to 1957, the year of the retirement of the council's first director, J. Lossing Buck. The chapter covers the role of John D. Rockefeller, III, the incorporation of the…

  12. The Agricultural Development Council. A History.

    Science.gov (United States)

    Stevenson, Russell; Locke, Virginia O.

    This history of the Agriculture Development Council (ADC) consists of eight chapters and four appendices. Chapter 1 traces the early years of the ADC, from its inception in 1953 to 1957, the year of the retirement of the council's first director, J. Lossing Buck. The chapter covers the role of John D. Rockefeller, III, the incorporation of the…

  13. 77 FR 2714 - National Petroleum Council

    Science.gov (United States)

    2012-01-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Office of Fossil Energy, Department of Energy. ACTION: Notice of Renewal... that the National Petroleum Council has been renewed for a two-year period, beginning January 12, 2012...

  14. 75 FR 48320 - National Petroleum Council

    Science.gov (United States)

    2010-08-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY National Petroleum Council AGENCY: Department of Energy, Office of Fossil Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the National Petroleum Council. The Federal Advisory...

  15. 77 FR 40400 - National Women's Business Council

    Science.gov (United States)

    2012-07-09

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business Administration. ACTION: Notice of... location, date, time, and agenda for the next meeting of the National Women's Business Council (NWBC)....

  16. 76 FR 37873 - National Women's Business Council

    Science.gov (United States)

    2011-06-28

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business Administration. ACTION: Notice of... location, date, time, ] and agenda for the next meeting of the National Women's Business Council...

  17. 76 FR 21786 - National Women's Business Council

    Science.gov (United States)

    2011-04-18

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION National Women's Business Council AGENCY: U.S. Small Business Administration. ACTION: Notice of... location, date, time, and agenda for the next meeting of the National Women's Business Council (NWBC)....

  18. 77 FR 19300 - National Infrastructure Advisory Council

    Science.gov (United States)

    2012-03-30

    ... SECURITY National Infrastructure Advisory Council AGENCY: National Protection and Programs Directorate, DHS... Infrastructure Advisory Council (NIAC) will meet on Tuesday, April 17, 2012, 1310 N. Courthouse Road, Suite 300, Virginia Room, Arlington, VA 22201. The meeting will be open to the public. DATES: The NIAC will...

  19. 77 FR 39247 - National Infrastructure Advisory Council

    Science.gov (United States)

    2012-07-02

    ... SECURITY National Infrastructure Advisory Council AGENCY: National Protection and Programs Directorate, DHS... Infrastructure Advisory Council (NIAC) will meet on Tuesday, July 17, 2012, at the Department of Transportation's... meeting will be open to the public. DATES: The NIAC will meet Tuesday, July 17, 2012, from 1:30 p.m. to...

  20. 78 FR 65675 - National Infrastructure Advisory Council

    Science.gov (United States)

    2013-11-01

    ... SECURITY National Infrastructure Advisory Council AGENCY: National Protection and Programs Directorate, DHS... Infrastructure Advisory Council (NIAC) will meet Thursday, November 21, 2013, at the United States Patent and... the public. DATES: The NIAC will meet Thursday, November 21, 2013, from 1:30 p.m. to 4:30 p.m....

  1. 78 FR 40487 - National Infrastructure Advisory Council

    Science.gov (United States)

    2013-07-05

    ... SECURITY National Infrastructure Advisory Council AGENCY: National Protection and Programs Directorate, DHS... Infrastructure Advisory Council (NIAC) will meet Monday, July 29, 2013, at the United States Access Board, 1331 F Street NW., Suite 800, Washington, DC 20004. The meeting will be open to the public. DATES: The NIAC...

  2. 77 FR 62521 - National Infrastructure Advisory Council

    Science.gov (United States)

    2012-10-15

    ... SECURITY National Infrastructure Advisory Council AGENCY: National Protection and Programs Directorate, DHS... Infrastructure Advisory Council (NIAC) will meet Tuesday, October 16, 2012, at the United States Access Board, 1331 F Street NW., Suite 800, Washington, DC 20004. The meeting will be open to the public. DATES:...

  3. 77 FR 67029 - NASA Advisory Council Meeting

    Science.gov (United States)

    2012-11-08

    ... SPACE ADMINISTRATION NASA Advisory Council Meeting AGENCY: National Aeronautics and Space Administration... amended, the National Aeronautics and Space Administration announces a meeting of the NASA Advisory Council. DATES: Wednesday, November 28, 2012, from 1:00 to 5:00 p.m. Thursday, November 29, 2012, from...

  4. 75 FR 4588 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2010-01-28

    ... SPACE ADMINISTRATION NASA Advisory Council; Meeting AGENCY: National Aeronautics and Space... newly formed Information Technology Infrastructure Committee of the NASA Advisory Council. This will be...-877-613-3958; 2939943. ADDRESSES: NASA Headquarters, 300 E Street, SW., Washington, DC, Room 2N35 FOR...

  5. 78 FR 72719 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2013-12-03

    ... SPACE ADMINISTRATION NASA Advisory Council; Meeting AGENCY: National Aeronautics and Space... NASA Advisory Council (NAC). DATES: Wednesday, December 11, 2013, 1:00 p.m.-5:15 p.m., Local Time; and Thursday, December 12, 2013, 9:00 a.m.-4:00 p.m., Local Time. ADDRESSES: NASA Kennedy Space Center...

  6. 76 FR 41825 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2011-07-15

    ... SPACE ADMINISTRATION NASA Advisory Council; Meeting AGENCY: National Aeronautics and Space... NASA Advisory Council (NAC). The agenda topics for the meeting will include: DATES: Thursday, August 4, 2011, 8 a.m.-5 p.m., and Friday, August 5, 2011, 8 a.m.-12 p.m., Local Time. ADDRESSES: NASA Ames...

  7. 75 FR 4875 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2010-01-29

    ... SPACE ADMINISTRATION NASA Advisory Council; Meeting AGENCY: National Aeronautics and Space... newly formed Education and Public Outreach Committee of the NASA Advisory Council. This will be the first meeting of this Committee. DATES: February 17, 2010--10 a.m.-4 p.m. (EST). ADDRESSES: NASA...

  8. 75 FR 39973 - NASA Advisory Council; Meeting

    Science.gov (United States)

    2010-07-13

    ... SPACE ADMINISTRATION NASA Advisory Council; Meeting AGENCY: National Aeronautics and Space... NASA Advisory Council. DATES: Thursday, August 5, 2010, 8 a.m.-5 p.m. (local time) Friday, August 6, 2010, 8 a.m.-12 a.m. (local time). ADDRESSES: NASA Jet Propulsion Laboratory, Von Karman Auditorium...

  9. 75 FR 2880 - Homeland Security Advisory Council

    Science.gov (United States)

    2010-01-19

    ... SECURITY Homeland Security Advisory Council AGENCY: The Office of Policy, DHS. ACTION: Committee management... providing strategic, timely and actionable advice. ] The HSAC will meet publicly to swear in new Council members, receive observations and remarks from DHS senior leadership, and review and...

  10. The European Divorce (Applicable Law Council Regulation (EU No 1259/2010 of 20 December 2010 Implementing Enhanced Cooperation in the Area of the Law Applicable to Divorce and Legal Separation

    Directory of Open Access Journals (Sweden)

    Crina Alina Tagarta (DE SMET

    2015-05-01

    Full Text Available The main objectives with this paper are to give a brief overview of the Scope of application of the regulation; of the main conflict-of-law rules adopted by the regulation, in special those that are more relevant to the role that a notary might have in an international divorce situation. The regulation provides citizens with appropriate outcomes in terms of legal certainty, predictability and flexibility, protects weaker partners during divorce disputes and prevents 'forum shopping'. This also helps avoiding complicated, lengthy and painful proceedings. More specifically, it allows international couples to agree in advance which law would apply to their divorce or legal separation as long as the agreed law is the law of the Member State which they have a closer connection with. In case the couple cannot agree, the judges can use a common formula for deciding which country's law applies. This paper will bring to light some risks and coordination difficulties with the regulation and a few matters that the regulation does not apply to.

  11. The ITER EC H&CD upper launcher: Structural design

    NARCIS (Netherlands)

    Spaeh, P.; Aiello, G.; de M. Baar,; Chavan, R.; Elzendoorn, B.; Goodman, T.; Henderson, M.; Kleefeldt, K.; Landis, J. D.; Meier, A.; Ronden, D.; Saibene, G.; Scherer, T.; Schreck, S.; Serikov, A.; Strauss, D.; Vaccaro, A.

    2011-01-01

    Four ITER EC H&CD (Electron Cyclotron Heating and Current Drive) Upper Launchers will be installed in the ITER Tokamak to counteract plasma instabilities by injection of up to 20 MW of millimeter-wave power at 170 GHz. Each Launcher features a structural system which is equipped with eight b

  12. The E-C Translation of Vocabularies in Sports News

    Institute of Scientific and Technical Information of China (English)

    何琳琳

    2014-01-01

    In recent years, many world top level sports events take place in China. The exchange in sports field between China and international society adds more significance to the E-C translation of sports news. This paper analyses the lexical features of sports news and then explains some difficulties in the translation of the words of sports news.

  13. EC-aided Gas Project Wound Up Satisfactorily

    Institute of Scientific and Technical Information of China (English)

    Wang Anfang

    1995-01-01

    @@ China and European Community signed an agreement on technical cooperation in March 1989,which offers China an EC aid of 2.6 million Ecu (3.32 million US dollars) for the energy project titled"Development of China's natural gas resources."

  14. EC-LEDS Supports the Low-Carbon Transition

    Energy Technology Data Exchange (ETDEWEB)

    2016-09-01

    EC-LEDS is a flagship U.S. government-led effort that assists countries to create and implement low emission development strategies, or LEDS -- development frameworks that promote sustainable social and economic development while reducing greenhouse gas emissions over the medium to long term.

  15. Genetic transformation of cry1EC gene into cotton (Gossypium ...

    African Journals Online (AJOL)

    welcome

    2013-04-10

    Apr 10, 2013 ... sp is not susceptible to Bt cotton containing Cry1Ac toxin so, there is ... encodes an insecticidal protein Cry1EC, (ii) 35S promoter from cauliflower ... the embryogenic calli were treated with the bacterial suspension by shaking ...

  16. EC-LEDS Mexico: Advancing Clean Energy Goals

    Energy Technology Data Exchange (ETDEWEB)

    2016-07-01

    EC-LEDS works with the government of Mexico to help meet its goals of reducing greenhouse gas emissions from the energy sector. The program targets specific, highly technical areas where Mexico has indicated the program can add value and make an impact.

  17. Notch-1-mediated esophageal carcinoma EC-9706 cell invasion and metastasis by inducing epithelial-mesenchymal transition through Snail.

    Science.gov (United States)

    Wang, Tao; Xuan, Xiaoyan; Pian, Linping; Gao, Ping; Hu, Hong; Zheng, Yuling; Zang, Wenqiao; Zhao, Guoqiang

    2014-02-01

    Notch has recently been shown to promote epithelial-to-mesenchymal transition (EMT) by involving in the EMT process that occurs during tumor progression and converts polarized epithelial cells into motile, invasive cells. However, it is still unclear whether the Notch signaling pathway is associated with the regulation of EMT in esophageal carcinoma. The present study explored Notch-1-mediated esophageal carcinoma EC-9706 cell invasion and metastasis by inducing epithelial–mesenchymal transition through Snail. The results demonstrated that the inhibition of Notch-1 expression in the esophageal carcinoma cell line EC-9706 could suppress the occurrence of EMT and at the same time could decrease the invasion and metastasis ability of the EC-9706 cells, indicative of its role in EMT. Snail is a transcriptional repressor of E-cadherin. We found that with the inhibition of Notch-1 expression in the esophageal carcinoma cell line EC-9706, the expression of Snail also decreased. Mechanistic studies showed that the up-expression of Snail in the EC-9706 cells restored the suppression of EMT regulated by Notch-1 inhibition, suggesting the role of Snail in Notch-1-mediated EMT. At the same time, the up-expression of Snail in the EC-9706 cells could also rescue the invasion and metastasis ability inhibited by Notch-1 siRNA. Taken together, our results had revealed that Notch-1 could participate in the invasion and metastasis of esophageal carcinoma through EMT via Snail. This study indicated that Notch-1 might be a useful target for esophageal carcinoma prevention and therapy.

  18. The effectiveness of the Arctic Council

    Directory of Open Access Journals (Sweden)

    Paula Kankaanpää

    2012-10-01

    Full Text Available Created in 1996, the Arctic Council has now been in operation long enough to justify a systematic effort to assess its effectiveness. To explore this topic, we created a questionnaire and circulated it to a large number of individuals who have participated in the work of the council in one capacity or another or who have followed the work of the council closely. This article analyses the quantitative and the qualitative input of those who responded to the questionnaire. The main conclusions are that: (1 the council has achieved considerable success in identifying emerging issues, framing them for consideration in policy venues and raising their visibility on the policy agenda and (2 changes now occurring in the Arctic will require significant adjustments to maintain the effectiveness of the council during the foreseeable future.

  19. 78 FR 48460 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2013-08-08

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... wildlife and habitat conservation endeavors that: 1. Benefit wildlife resources; 2. Encourage...

  20. 78 FR 25463 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2013-05-01

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... advice about wildlife and habitat conservation endeavors that: 1. Benefit wildlife resources;...

  1. 77 FR 57577 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-09-18

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... wildlife and habitat conservation endeavors that: 1. Benefit wildlife resources; 2. Encourage...

  2. 78 FR 73205 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2013-12-05

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... advice about wildlife and habitat conservation endeavors that: 1. Benefit wildlife resources;...

  3. 77 FR 10543 - Wildlife and Hunting Heritage Conservation Council Charter

    Science.gov (United States)

    2012-02-22

    ... Office of the Secretary Wildlife and Hunting Heritage Conservation Council Charter AGENCY: Office of the... Secretary of Agriculture have renewed the Wildlife and Hunting Heritage Conservation Council (Council..., providing recommendations for: (a) Implementing the Recreational Hunting and Wildlife Resource...

  4. 77 FR 4370 - NASA Advisory Council; Commercial Space Committee; Meeting

    Science.gov (United States)

    2012-01-27

    ... SPACE ADMINISTRATION NASA Advisory Council; Commercial Space Committee; Meeting AGENCY: National... announces a meeting of the Commercial Space Committee (CSC) of the NASA Advisory Council (NAC). DATES... Admission to the NASA Advisory Council (NAC) Commercial Space Committee (CSC).'' For security...

  5. 78 FR 31519 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-05-24

    ... England Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS...: The New England Fishery Management Council's (Council) Groundfish Oversight Committee will meet to... held at the Providence Biltmore Hotel, 11 Dorrance Street, Providence, RI 02903; telephone: (401) 421...

  6. 75 FR 34479 - Meeting Announcement: North American Wetlands Conservation Council

    Science.gov (United States)

    2010-06-17

    ... Fish and Wildlife Service Meeting Announcement: North American Wetlands Conservation Council AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of meeting. SUMMARY: The North American Wetlands Conservation Council (Council) will meet to select North American Wetlands Conservation Act (NAWCA)...

  7. 78 FR 11220 - Meeting Announcement: North American Wetlands Conservation Council

    Science.gov (United States)

    2013-02-15

    ... Fish and Wildlife Service Meeting Announcement: North American Wetlands Conservation Council AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of meeting. SUMMARY: The North American Wetlands Conservation Council (Council) will meet to select North American Wetlands Conservation Act (NAWCA)...

  8. 77 FR 71820 - Meeting Announcement: North American Wetlands Conservation Council

    Science.gov (United States)

    2012-12-04

    ... Fish and Wildlife Service Meeting Announcement: North American Wetlands Conservation Council AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of meeting. SUMMARY: The North American Wetlands Conservation Council (Council) will meet to select North American Wetlands Conservation Act (NAWCA)...

  9. 77 FR 39252 - Meeting Announcement: North American Wetlands Conservation Council

    Science.gov (United States)

    2012-07-02

    ... Fish and Wildlife Service Meeting Announcement: North American Wetlands Conservation Council AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of meetings. SUMMARY: The North American Wetlands Conservation Council (Council) will meet to select North American Wetlands Conservation Act (NAWCA)...

  10. 76 FR 31626 - Meeting Announcement; North American Wetlands Conservation Council

    Science.gov (United States)

    2011-06-01

    ... Fish and Wildlife Service Meeting Announcement; North American Wetlands Conservation Council AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of meeting. SUMMARY: The North American Wetlands Conservation Council (Council) will meet to select North American Wetlands Conservation Act (NAWCA)...

  11. 76 FR 64073 - New England Fishery Management Council; Public Meetings

    Science.gov (United States)

    2011-10-17

    ... Administration (NOAA), Commerce. ACTION: Notice; public meetings. SUMMARY: The New England Fishery Management... National Oceanic and Atmospheric Administration RIN 0648-XA763 New England Fishery Management Council... locations, see SUPPLEMENTARY INFORMATION. Council address: New England Fishery Management Council, 50...

  12. The European "clinical trial" regulation; relationship with the Jardé Act: a Giens workshop.

    Science.gov (United States)

    Lemaire, François; Marchenay, Brigitte; Chassany, Olivier; Barthélémy, Philippe; Bouzzagou, Mohamed; Comet, Denis; Delval, Cécile; Dubray, Claude; Fouret, Cécile; Frija-Orvoen, Elisabeth; Gambotti, Laetitia; Lamarque, Véronique; d'Orsay, Geneviève; Plattner, Valérie; Sibenaler, Claire; Roux, Jacques; Thoby, Frédérique

    2015-01-01

    In May 2014, the European Union Parliament and Council published a new regulation on clinical trials on medicinal products for human use, which is designed to replace Directive 2001/20/EC. It will not come into effect until 2016. Nevertheless, it is essential to examine its relationship with national legislation, i.e. the Jardé Act, whose implementation has been delayed pending publication of the European regulation. The Giens workshop identified and examined the various issues that this relationship is bound to raise. In particular, it looked at trial methodology assessment procedures, the working relationship between the French National Agency of Drug Safety and Health Products (Agence Nationale de Sécurité du Médicament et des Produits de Santé, ANSM) and ethics committees during the authorization application evaluation phase, review of post-authorization/registration studies on medicinal products and medical devices, and data transparency.

  13. New EC Directive on the limitation of emissions from large combustion plants. Implications for German power plants; Neue EG-Richtlinie ueber nationale Emissionshoechstmengen. Folgerung fuer deutsche Kraftwerke

    Energy Technology Data Exchange (ETDEWEB)

    Hildebrand, M. [VDEW - e.V., Frankfurt am Main (Germany). Bereich Recht und Umwelt

    2002-03-25

    The Directive 2001/80/EC of the European Parliament and of the Council, on the limitation of emissions of certain pollutants into the air from large combustion plants uses a regulatory instrument for limiting emissions at the national levels of EU member states. This approach is completely new and the author of this article therefore expects problems to arise in the context of transfer of this EC Directive into national law. Another aspect discussed is the assessment of implications for the operating power plants in Germany. (orig./CB) [German] Mit der im Herbst 2001 durch das Europaeische Parlament und durch den Umweltministerrat verabschiedeten Richtlinie ueber nationale Emissionshoechstmengen wurde vom europaeischen Vorschriftengeber ein in Deutschland bislang systemfremdes Regelungsinstrument geschaffen, dessen Umsetzung in nationales Recht und dessen anlagenspezifische Konsequenzen - zumindest hierzulande -bislang noch reichlich unklar sind. (orig.)

  14. Seizure threshold to lidocaine is decreased following repeated ECS (electroconvulsive shock)

    DEFF Research Database (Denmark)

    Kragh, J; Seidelin, J; Bolwig, T G

    1993-01-01

    Seizure susceptibility to lidocaine was investigated in rats which had received repeated ECS (electroconvulsive shock). In the first experiment three groups of rats received an ECS daily for 18 days, an ECS weekly for 18 weeks, and 18 sham treatments, respectively. Twelve weeks after the last ECS...

  15. Seizure threshold to lidocaine is decreased following repeated ECS (electroconvulsive shock)

    DEFF Research Database (Denmark)

    Kragh, J; Seidelin, J; Bolwig, T G

    1993-01-01

    Seizure susceptibility to lidocaine was investigated in rats which had received repeated ECS (electroconvulsive shock). In the first experiment three groups of rats received an ECS daily for 18 days, an ECS weekly for 18 weeks, and 18 sham treatments, respectively. Twelve weeks after the last ECS...

  16. Achievements and bottlenecks in humanitarian demining EU-funded research: final results from the EC DELVE project

    Science.gov (United States)

    Sahli, Hichem; Bruschini, Claudio; Van Kempen, Luc; Schleijpen, Ric; den Breejen, Eric

    2008-04-01

    The EC DELVE Support Action project has analyzed the bottlenecks in the transfer of Humanitarian Demining (HD) technology from technology development to the use in the field, and drawn some lessons learned, basing itself on the assessment of the European Humanitarian Demining Research and Technology Development (RTD) situation from early 1990 until 2006. The situation at the European level was analyzed with emphasis on activities sponsored by the European Commission (EC). This was also done for four European countries and Japan, with emphasis on national activities. The developments in HD during the last 10 years underline the fact that in a number of cases demining related developments have been terminated or at least put on hold. The study also showed that the funding provided by the EC under the Framework Program for RTD has led directly to the creation of an extensive portfolio of Humanitarian Demining technology development projects. The latter provided a range of research and supporting measures addressing the critical issues identified as a result of the regulatory policies developed in the field of Humanitarian Demining over the last ten years. However, the range of instruments available to the EC to finance the necessary research and development were limited, to pre-competitive research. The EC had no tools or programs to directly fund actual product development. As a first consequence, the EC funding program for development of technology for Humanitarian Demining unfortunately proved to be largely unsuitable for the small-scale development needed in a field where there is only a very limited market. As a second consequence, most of the research has been demonstrator-oriented. Moreover, the timeframe for RTD in Humanitarian Demining has not been sufficiently synchronized with the timeframe of the EC policies and regulations. The separation of the Mine Action and RTD funding streams in the EC did also negatively affect the take-up of new technologies. As a

  17. Evaluation of the size segregation of elemental carbon (EC) emission in Europe: Influence on the simulation of EC long-range transportation

    NARCIS (Netherlands)

    Chen, Y.; Cheng, Y.F.; Nordmann, S.; Birmili, W.; Denier Van Der Gon, H.A.C.; Ma, N.; Wolke, R.; Wehner, B.; Sun, J.; Spindler, G.; Mu, Q.; Pöschl, U.; Su, H.; Wiedensohler, A.

    2016-01-01

    Elemental Carbon (EC) has a significant impact on human health and climate change. In order to evaluate the size segregation of EC emission in the EUCAARI inventory and investigate its influence on the simulation of EC long-range transportation in Europe, we used the fully coupled online Weather

  18. Evaluation of the size segregation of elemental carbon (EC) emission in Europe: Influence on the simulation of EC long-range transportation

    NARCIS (Netherlands)

    Chen, Y.; Cheng, Y.F.; Nordmann, S.; Birmili, W.; Denier Van Der Gon, H.A.C.; Ma, N.; Wolke, R.; Wehner, B.; Sun, J.; Spindler, G.; Mu, Q.; Pöschl, U.; Su, H.; Wiedensohler, A.

    2016-01-01

    Elemental Carbon (EC) has a significant impact on human health and climate change. In order to evaluate the size segregation of EC emission in the EUCAARI inventory and investigate its influence on the simulation of EC long-range transportation in Europe, we used the fully coupled online Weather Res

  19. Scientific Opinion on the substantiation of a health claim related to the combination of artichoke leaf dry extract standardised in caffeoylquinic acids, monacolin K in red yeast rice, sugar-cane derived policosanols, OPC from French maritime pine bark, garlic dry extract standardised in allicin, d-α-tocopheryl hydrogen succinate, riboflavin and inositol hexanicotinate in Limicol® and reduction of blood LDL-cholesterol concentrations pursuant to Article 14 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2013-07-01

    Full Text Available Following an application from Laboratoire Lescuyer, submitted pursuant to Article 14 of Regulation (EC No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to the combination of artichoke leaf dry extract standardised in caffeoylquinic acids, monacolin K in red yeast rice, sugar-cane derived policosanols, OPC from French maritime pine bark, garlic dry extract standardised in allicin, d-α-tocopheryl hydrogen succinate, riboflavin and inositol hexanicotinate in Limicol® and reduction of blood LDL-cholesterol concentrations. The Panel considers that the food which is the subject of the claim is sufficiently characterised. The Panel considers that reduction of blood LDL-cholesterol concentrations is a beneficial physiological effect. High LDL-cholesterol is a risk factor in the development of coronary heart disease. In weighing the evidence, the Panel took into account that, although no evidence was provided for an LDL-cholesterol lowering effect of any of the single food constituents in Limicol® at the proposed conditions of use or as to how the ingredients individually or in any combination could contribute to the claimed effect and despite the lack of a dose-response relationship observed in one human intervention study, three human intervention studies conducted by two independent research groups showed an effect of the combination of food ingredients in Limicol® on blood LDL-cholesterol concentrations. The Panel concludes that a cause and effect relationship has been established between the consumption of the combination of artichoke leaf dry extract standardised in caffeoylquinic acids, monacolin K in red yeast rice, sugar-cane derived policosanols, OPC from French maritime pine bark, garlic dry extract standardised in allicin, d-α-tocopheryl hydrogen succinate, riboflavin and inositol

  20. Scientific Opinion on the substantiation of a health claim related to fat-free yogurts and fermented milks with live yogurt cultures complying with the specifications ?fat free?, ?low in sugars?, ?high protein?, ?source of calcium? and ?source of vitamin D? for nutrition claims and maintenance of lean body mass in the context of an energy-restricted diet pursuant to Article 13.5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2015-01-01

    Full Text Available Following an application from Federación Nacional de Industrias Lácteas (FeNIL, submitted pursuant to Article 13.5 of Regulation (EC No 1924/2006 via the Competent Authority of Spain, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to fat-free yogurts and fermented milks with live yogurt cultures complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims and maintenance of lean body mass in the context of an energy-restricted diet. The Panel considers that the food that is the subject of the claim, fat-free yogurts and fermented milks complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims, is sufficiently characterised. The Panel considers that maintenance of lean body mass in the context of an energy-restricted diet is a beneficial physiological effect. No human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim were provided. The Panel concludes that a cause and effect relationship has not been established between the consumption of fat-free yogurts and fermented milks with live yogurt cultures complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims and maintenance of lean body mass in the context of an energy-restricted diet.

  1. EC,ASMC and Macrophage Oxidize Human Low Density Lipoprotein

    Institute of Scientific and Technical Information of China (English)

    Dai Zhao-ming; Wu Jun-zhu; Li Xiao-ming; Chen Li-da; Hong Jia-ling

    2003-01-01

    To investigate the mechanism of LDL oxidation in vivo , LDL was incubated with endothelium cell (EC),artery smooth muscle cell (ASMC) and macrophage, and then the change of myeloperoxidase (MPO) activity in cell and medium and the oxidation of LDL by those three cells were assessed. The result showed that LDL promoted the activity of cellular and secretive myeloperoxidase which was concentration-dependent on LDL; with elevation of MPO activity, oxidation of LDL intensified, which was expressed by the formation of conjugated dienes and the elevation of thiobarbituric acid teactive substance (TBARS). Macrophage's MPO activity went up with the increase of LDL at both low and high concentration; EC's MPO activity went up with the increase of LDL only at high concentration and ASMC's MPO activity wasn't sensitive to LDL concentration change. The results suggest that Macrophage might be crucial to the oxidation of LDL in vivo, in which MPO might play an important role.

  2. EC,ASMC and Macrophage Oxidize Human Low Density Lipoprotein

    Institute of Scientific and Technical Information of China (English)

    Dai; Zhao-ming; Wu; Jun-zhu; 等

    2003-01-01

    To investigate the mechanism of LDL oxidation in vivo, LDL was incubated with endothelium cell (EC),artery smooth muscle cell (ASMC) and macrophage, and then the change of myeloperoxidase (MPO) activity in cell and medium and the oxidation of LDL by those three cells were assessed. The result showed that LDL promoted the activity of cellular and secretive myeloperoxidase which was concentration-dependent on LDL; with elevation of MPO activity, oxidation of LDL intensified, which was expressed by the formation of conjugated dienes and the elevation of thiobarbituric acid teactive substance (TBARS). Macrophage's MPO activity went up with the increase of LDL at both low and high concentration; EC's MPO activity went up with the increase of LDL only at high concentration and ASMC's MPO activity wasn't sensitive to LDL concentration change. The results LDL in vivo, in which MPO might play an important role.

  3. X-ray spectroscopy in the EC nucleus

    Science.gov (United States)

    Ko, Seung Kook; Cho, Hyun Jae; Nha, Sang Kyun

    1998-10-01

    The probabilities PKK of double K-shell vacancy production per K electron capture decay and per K internal conversion of 109Cd and 207Bi have been determined by means of the double- and triple-coincidence experiments using Kα X-ray and K internal conversion. For 109Cd we find PKK(EC) = (4.2 ± 0.5) × 10 -5 and PKK(IC) = (4.32 ± 0.46) × 10 -5, and for 207Bi, PKK(EC) = (2.54 ± 0.50) × 10 -5. The observed X-ray energy shifts of the hypersatellite Ag ( Kα1H) X-ray and the hypersatellite Pb ( Kα1H) X-ray lines are 545±15 eV and 1238±45 eV, respectively.

  4. Nanoscale Bio-Molecular Control Using EC-OWLS

    Energy Technology Data Exchange (ETDEWEB)

    Bearinger, J P; Voros, J; Hubbell, J A; Textor, M

    2002-11-20

    A recently developed technique termed ''Electrochemical Optical Waveguide Lightmode Spectroscopy'' (EC-OWLS) [1] combines evanescent-field optical sensing with electrochemical control of surface adsorption processes. Initial EC-OWLS investigations efficiently monitored molecular surface adsorption and layer thickness changes of an adsorbed polymer layer examined in situ as a function of potential applied to a waveguide1. A layer of indium tin oxide (ITO) served as both a high refractive index waveguide for optical sensing, and a conductive electrode; an electrochemical flow-through fluid cell incorporated working, reference and counter electrodes. Poly(L-lysine)-grafted-poly(ethylene glycol) (PLL-g-PEG) served as a model, polycation adsorbate. Results indicate that adsorption and desorption of PLL-g-PEG from aqueous buffer are a function of applied potential, and that binding events subsequent to PLL-g-PEG functionalization are dependent on reorganization in the molecular adlayer.

  5. Reshaping Text Data for Efficient Processing on Amazon EC2

    OpenAIRE

    Gabriela Turcu; Ian Foster; Svetlozar Nestorov

    2011-01-01

    Text analysis tools are nowadays required to process increasingly large corpora which are often organized as small files (abstracts, news articles, etc.). Cloud computing offers a convenient, on-demand, pay-as-you-go computing environment for solving such problems. We investigate provisioning on the Amazon EC2 cloud from the user perspective, attempting to provide a scheduling strategy that is both timely and cost effective. We derive an execution plan using an empirically determined applicat...

  6. Environmental Quality Standards in the EC-Water Framework Directive

    DEFF Research Database (Denmark)

    Jirka, Gerhard H.; Burrows, Richard; Larsen, Torben

    2004-01-01

    The "combined approach" in the new EC-Water Framework Directive(WFD) consisting of environmental quality standards in addition to emission limit values promises improvements in the quality characteristics of surface water. However, the specification of where in the water body the environmental...... waters, respectively. Furthermore, water authorities will have to make increased use of predictive modeling techniques for the implementation of the "combined appraoch"....

  7. Environmental Quality Standards in the EC-Water Framework Directive

    DEFF Research Database (Denmark)

    Jirka, Gerhard H.; Burrows, Richard; Larsen, Torben

    2004-01-01

    The "combined approach" in the new EC-Water Framework Directive(WFD) consisting of environmental quality standards in addition to emission limit values promises improvements in the quality characteristics of surface water. However, the specification of where in the water body the environmental...... waters, respectively. Furthermore, water authorities will have to make increased use of predictive modeling techniques for the implementation of the "combined appraoch"....

  8. On E-C Translation of Proprietary Business Brand Terms

    Institute of Scientific and Technical Information of China (English)

    JIA Jun-min; ZHAO Wan-li

    2015-01-01

    An excellent translation of proprietary business brand terms is more important in international trade. Diverse cultural backgrounds and purposiveness of products are the most influential factors. The research tries to analyze the elements of cultural background and aims of products that affect E-C translation of proprietary business brand terms by descriptive study method and experience summary method, and then to provide methods to overcome these difficulties.

  9. 2013 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2013-01-01

    Elections Timetable Starting with Echo of 16 September, posters, etc. call for applications Monday 21 October, at noon closing date for receipt of the applications Monday 28 October, at noon start date for voting Monday 11 November, at noon closing date for voting Monday 18 and Monday 25 November, publication of the results in Echo Tuesday 19 November Staff Association Assizes Tuesday 3 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure is monitored by the Election Committee, which is also in charge of announcing the results in Echo on 18 and 25 November. n its meeting on 11 September 2013, the Electoral Commission decided on the following distribution of seats in colleges O.1 to O.6: Sectors Departments Career paths AA – A – B – C – D Career paths E – F – G – H Accelerators and Technology BE TE EN Electoral college 0.1 13 si&...

  10. 2011 Elections to Staff Council

    CERN Multimedia

    Association du personnel

    2011-01-01

    Elections Timetable Starting with Echo of 26 September, posters, etc. call for applications Wednesday 26 October, at noon closing date for receipt of the application Monday 31 October, at noon start date for voting Monday 14 November, at noon closing date for voting Monday 21 November, publication of the results in Echo Tuesday 22 and Wednesday 29 November Staff Association Assizes Tuesday 6 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure will be monitored by the Election Committee, which is also in charge of announcing the results in Echo on 21 November. In its meeting on 19 September 2011, the Electoral Commission decided on the following distribution of seats in colleges 0.1 to 0.6: Sector Department Career path AA – A – B – C – D Career path E – F – G – H Accelerators and Technology BE TE EN Electoral college 0.1 18 si&e...

  11. 2013 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2013-01-01

    Elections Timetable Starting with Echo of 16 September, posters, etc. call for applications Monday 21 October, at noon closing date for receipt of the applications Monday 28 October, at noon start date for voting Monday 11 November, at noon closing date for voting Monday 18 and Monday 25 November, publication of the results in Echo Tuesday 19 November Staff Association Assizes Tuesday 3 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure is monitored by the Election Committee, which is also in charge of announcing the results in Echo on 18 and 25 November. n its meeting on 11 September 2013, the Electoral Commission decided on the following distribution of seats in colleges O.1 to O.6: Sectors Departments Career paths AA – A – B – C – D Career paths E – F – G – H Accelerators and Technology BE TE EN Electoral colle...

  12. 2011 Elections to Staff Council

    CERN Multimedia

    Staff Association

    2011-01-01

    Elections Timetable Starting with Echo of 26 September, posters, etc. call for applications Wednesday 26 October, at noon closing date for receipt of the application Monday 31 October, at noon start date for voting Monday 14 November, at noon closing date for voting Monday 21 November, publication of the results in Echo Tuesday 22 and Wednesday 29 November Staff Association Assizes Tuesday 6 December, at 10.00 a.m. first meeting of the new Staff Council and election of the new Executive Committee The voting procedure will be monitored by the Election Committee, which is also in charge of announcing the results in Echo on 21 November. In its meeting on 19 September 2011, the Electoral Commission decided on the following distribution of seats in colleges 0.1 to 0.6: Sector Department Career path AA – A – B – C – D Career path E – F – G – H Accelerators and Technology BE TE EN Electoral college 0.1 18 si&e...

  13. Emergency EC-IC bypass for symptomatic atherosclerotic ischemic stroke.

    Science.gov (United States)

    Horiuchi, Tetsuyoshi; Nitta, Junpei; Ishizaka, Shigetoshi; Kanaya, Kohei; Yanagawa, Takao; Hongo, Kazuhiro

    2013-10-01

    Previous studies have shown that extracranial-intracranial (EC-IC) bypass surgery has no preventive effect on subsequent ipsilateral ischemic stroke in patients with symptomatic atherosclerotic internal carotid occlusion and hemodynamic cerebral ischemia. A few studies have assessed whether an urgent EC-IC bypass surgery is an effective treatment for main trunk stenosis or occlusion in acute stage. The authors retrospectively reviewed 58 consecutive patients who underwent urgent EC-IC bypass for symptomatic internal carotid artery or the middle cerebral artery stenosis or occlusion between January 2003 and December 2011. Clinical characteristics and neuroimagings were evaluated and analyzed. Based on preoperative angiogram, responsible lesions were the internal carotid artery in 19 (32.8%) patients and the middle cerebral artery in 39 (67.2%). No hemorrhagic complication occurred. Sixty-nine percent of patients showed improvement of neurological function after surgery, and 74.1% of patients had favorable outcome. Unfavorable outcome was associated with insufficient collateral flow and new infarction after bypass surgery.

  14. ESO Council Decides to Continue VLT Project at Paranal

    Science.gov (United States)

    1994-08-01

    to complete negotiation of a Supplementary and Amending Agreement and it was decided that a Council Delegation shall conclude as soon as possible the negotiation of this Agreement. Council noted that the Chilean Delegation has accepted ESO's invitation to hold the final round of negotiations in Europe and proposed that this final round shall be held in the period Sept. 15 - Oct. 15, 1994. Nonetheless, Council also expressed its preoccupation with regard to remaining ambiguities contained in some official statements according to which the formal recognition of ESO's status on Paranal would depend on the conclusion of the above mentioned Agreement. At the May 1994 meetings in Santiago [2], understanding had been reached that this Agreement will merely confirm the already existing legal situation. The main objective is to expand the cooperation between Chile and ESO by granting ensured access for Chilean astronomers to ESO's facilities and incorporate elements of Chilean labour legislation into the ESO internal staff regulations. In view of these circumstances, and pending the successful conclusion of these negotiations, Council therefore instructed the ESO Management to continue exploring alternative sites for the VLT. In a final statement, the ESO Council again expressed its hope that the scientific co-operation between Europe and Chile in the field of astronomy which began in 1963 will continue to develop and expand well into the next century to the mutual benefit of science in both communities. CONTINUATION OF THE VLT PROJECT In practical terms, the above decision by Council implies that ESO will now initiate the steps necessary to move from Europe to Paranal the main mechanical parts of the rotating dome (total weight around 500 tonnes) for the first VLT 8.2-metre unit telescope. It is expected that the sea transport will take place in September-October of this year and that assembly at Paranal will begin soon thereafter, once the concrete base, now under

  15. An approach to the implementation of European Directive 2007/60/EC on flood risk management in the Czech Republic

    Directory of Open Access Journals (Sweden)

    A. Dráb

    2010-09-01

    Full Text Available Directive 2007/60/EC of the European Parliament and of the Council of 23 October 2007 on the assessment and management of flood risks (the Flood Risk Directive signifies that flood risk analysis methods are gaining ground in EC Member States and, therefore, also in the Czech Republic (CR. Procedures of flood risk analysis have been developed in the Czech Republic since the catastrophic floods of 1997 in line with European and worldwide trends and have been tested and applied in hundreds of case studies to date. Currently, the Flood Risk Directive Guideline based on past experience with flood risk analysis applications is being processed.

    The aim of the paper is to present flood risk analysis procedures and specially developed techniques for the assembly of flood hazard, danger and flood risk maps. Methods related to flood risk management plans are briefly mentioned as well. The following particular problems are discussed in more detail: an application and extension of the "danger matrix" approach, the definition of residual danger, the formulation of efficiency criteria and preliminary multi-criteria flood risk assessment. These issues were tested in practical applications at pilot locations in the Czech Republic. Present experience provides evidence that the flood risk analysis methods used in the Czech Republic are in harmony with the requirements of the Flood Risk Directive. The proposed and applied methods are based primarily on existing available data such as flood extent maps, cadastral maps, the Register of Census Districts and Structures and others.

  16. Principles for shaping working conditions according to ILO conventions and EC directives.

    Science.gov (United States)

    Koradecka, D

    2001-01-01

    The strategy for the improvement of occupational safety and health is presented. The role of the state and the workers in shaping working conditions has changed over the years, and this process is traced through ILO and EC documents. There must be a coherent up-to-date national policy in this field. Safety and the protection of the workers' health is perceived by the Community legislation not only in the terms of the worker's individual interest, but also from a social viewpoint, consisted in striving for general improvement of the work environment. The Community regulations aspire to satisfy the public interest, and directives set the maximum level of protection but also serve as minimum standards not infringing the more favourable national regulations. They define requirements that should already be met at the planning and designing stages.

  17. The ITER EC H and CD upper launcher: Structural system

    Energy Technology Data Exchange (ETDEWEB)

    Spaeh, Peter, E-mail: peter.spaeh@kit.edu [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Aiello, Gaetano; Gessner, Robby; Grossetti, Giovanni; Meier, Andreas; Scherer, Theo; Schreck, Sabine [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Serikov, Arkady [Karlsruhe Institute of Technology, Institute for Neutron Physics and Reactor Technology, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Strauss, Dirk; Vaccaro, Alessandro [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Weinhorst, Bastian [Karlsruhe Institute of Technology, Institute for Neutron Physics and Reactor Technology, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany)

    2013-10-15

    Highlights: ► ITER EC H and CD Launcher goes towards final design. ► European consortium founded for bringing the EC H and CD launcher towards final design. ► New design updates for dedicated components of the ITER EC H and CD launcher. -- Abstract: After approval of the preliminary design of the ITER EC H and CD Upper Launcher, ECHUL-CA, a consortium of several European research institutes, was founded to pool resources for approaching the final design. At the end of 2011 the consortium has signed a 2 years contract with F4E to go ahead with the work on the launcher. The contract deals with design work on both the port plug, forming the structural system, and the mm-wave-system, which injects the RF-power into the plasma. Within the period of this contract all components being part of the Tritium confinement, of which the closure plate, the support flange, the diamond windows and the waveguide feed-throughs are the most outstanding ones, will get the status of the final design. Important steps to be done for the structural system are the optimization of the mechanical behavior of the launcher, leading to minimum deflections of the port plug during plasma disruptions and optimum seismic resistance. To reduce the effect of halo currents it was decided to recess the first wall of 100 mm compared to the regular blanket tangent. This recess requires substantial changes of the cooling system and the thermo-hydraulic design of the launcher. Also the layout of the shielding arrangement and the integration of the mm-wave system need significant revision. Moreover manufacturing aspects and enhanced remote handling capability are taken into account. For the final design also quality aspects must be considered; thus the design is elaborated with respect to applicable codes and standards, material specifications, risk analyses and the RAMI (reliability, availability, maintainability and inspectability) analysis to guarantee maximum performance of the device. This paper

  18. 78 FR 68077 - Navigation Safety Advisory Council

    Science.gov (United States)

    2013-11-13

    ... Study (ACPARS). The Council will receive an update on the ACPARS undertaken to accommodate offshore wind..., and those expected to commence in calendar year 2014. (4) Navigation Rules Regulatory Project....

  19. 76 FR 36137 - National Infrastructure Advisory Council

    Science.gov (United States)

    2011-06-21

    ... Infrastructure Advisory Council (NIAC) will meet on Tuesday, July 12, 2011, at the Washington Marriott at Metro... NIAC@dhs.gov . ADDRESSES: The meeting will be held at the Washington Marriott at Metro Center, Salon...

  20. Appeals Council Requests - Average Processing Time

    Data.gov (United States)

    Social Security Administration — This dataset provides annual data from 1989 through 2015 for the average processing time (elapsed time in days) for dispositions by the Appeals Council (AC) (both...

  1. [Bioethics in the Council of Europe].

    Science.gov (United States)

    Chatzixiros, Efstratios

    2015-12-01

    The Council is an intergovernmental institution that actively defends human rights in biomedicine through its experts' Committee on Bioethics. The field of biomedical science and technology is in constant development. Bioethics provisions must take account.

  2. 76 FR 9765 - National Coal Council

    Science.gov (United States)

    2011-02-22

    ... presentation on the new study conducted by the Council on the deployment of carbon capture and storage... Grahame of the Department of Energy on the impacts of black carbon in the atmosphere. Other...

  3. Fiscal autonomy of urban councils in Zimbabwe

    African Journals Online (AJOL)

    LAW

    2 Ministry of Local Government “Fiscal autonomy for urban councils? ... majority of those voting in a referendum chose self-rule rather than being incorporated into the Union of ..... In practice, the Ministers of Local Government and Finance.

  4. CDA Judicial Council: blending idealism and practicality.

    Science.gov (United States)

    Kiger, Robert D

    2013-07-01

    The California Dental Association Judicial Council has the responsibility for interpreting and enforcing the Code of Ethics, for disciplining members and for fostering a climate of education and ethics awareness for CDA members. The Council recognizes the inherent difficulty in rigid enforcement of the Code of Ethics, and chooses to take an approach that educates and encourages members to embrace the highest standards of our profession as outlined in the Code.

  5. Opening of the 123rd Council session

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The CERN Council held its 123rd session on 13 December 2002 under the chairmanship of Professor Maurice Bourquin. The election of the next Director General, the Baseline Plan for 2003-2010 and a new status for non-European states were among the items agreed. Photo 01: (left to right) Director-General Prof. Luciano Maiani, President of Council Prof. Maurice Bourquin, and Director of administration Jan van der Boon.

  6. Business-to-business electronic commerce systems and services. Smart EC solution; Kigyoka nrenkei system solution system. Smart EC solution

    Energy Technology Data Exchange (ETDEWEB)

    Setoguchi, T.; Manchu, Y.; Katsumata, M. [Toshiba Corp., Tokyo (Japan)

    2000-04-01

    Toshiba provides a range of information technology (IT) solutions called SmartEC Solution, which includes business-to-business electronic commerce systems and services based on international standards and industrial know-how, especially our electronic data interchange (EDI) know-how as a manufacturer. These IT solutions are supplied as services covering strategy planning, system integration, and application service provider based on five types of business-to-business electronic commerce. (author)

  7. 78 FR 64199 - Fisheries of the South Atlantic; South Atlantic Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-10-28

    .... SUMMARY: The South Atlantic Fishery Management Council's (Council) Scientific and Statistical Committee... Atlantic Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS...: (800) 445-8667 or (843) 308- 9330. Council address: South Atlantic Fishery Management Council,...

  8. 78 FR 80367 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-72; Introduction

    Science.gov (United States)

    2013-12-31

    ...This document summarizes the Federal Acquisition Regulation (FAR) rules agreed to by the Civilian Agency Acquisition Council and the Defense Acquisition Regulations Council (Councils) in this Federal Acquisition Circular (FAC) 2005-72. A companion document, the Small Entity Compliance Guide (SECG), follows this FAC. The FAC, including the SECG, is available via the Internet at......

  9. 75 FR 22423 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2010-04-28

    ... Fish and Wildlife Service Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife... public meeting of the Sport Fishing and Boating Partnership Council (Council). DATES: The meeting will be... announce that the Sport Fishing and Boating Partnership Council will hold a meeting. Background The...

  10. 76 FR 75898 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2011-12-05

    ... Fish and Wildlife Service Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife... (Service), announce a public teleconference of the Sport Fishing and Boating Partnership Council (Council.... The Council represents the interests of the public and private sectors of the sport fishing,...

  11. 78 FR 4161 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-01-18

    ... Fish and Wildlife Service Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife... (Service), announce a public teleconference of the Sport Fishing and Boating Partnership Council (Council.... App., we announce that Sport Fishing and Boating Partnership Council will hold a...

  12. 75 FR 47624 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2010-08-06

    ... Fish and Wildlife Service Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife... public meeting of the Sport Fishing and Boating Partnership Council (Council). DATES: The meeting will be.... App., we announce that the Sport Fishing and Boating Partnership Council will hold a meeting...

  13. 78 FR 33856 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-06-05

    ...; FF09X60000-FVWF97920900000-XXX] Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife... (Service), announce a public teleconference of the Sport Fishing and Boating Partnership Council (Council... Act, 5 U.S.C. App., we announce that Sport Fishing and Boating Partnership Council will hold...

  14. 77 FR 61626 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2012-10-10

    ... Fish and Wildlife Service Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife...), announce a public meeting of the Sport Fishing and Boating Partnership Council (Council). A Federal.... App., we announce that the Sport Fishing and Boating Partnership Council will hold a...

  15. 77 FR 26784 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2012-05-07

    ... Fish and Wildlife Service Sport Fishing and Boating Partnership Council AGENCY: Fish and Wildlife... (Service), announce a public teleconference of the Sport Fishing and Boating Partnership Council (Council.... App., we announce that Sport Fishing and Boating Partnership Council will hold a...

  16. 77 FR 4575 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2012-01-30

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... Wildlife and Hunting Heritage Conservation Council will hold a meeting. Background Formed in February...

  17. 76 FR 66955 - Wildlife and Hunting Heritage Conservation Council

    Science.gov (United States)

    2011-10-28

    ... Fish and Wildlife Service Wildlife and Hunting Heritage Conservation Council AGENCY: Fish and Wildlife... public meeting of the Wildlife and Hunting Heritage Conservation Council (Council). DATES: Meeting... Wildlife and Hunting Heritage Conservation Council will hold a meeting. Background Formed in February...

  18. 50 CFR 600.245 - Council member compensation.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Council Membership § 600.245 Council member compensation. (a) All voting Council members whose eligibility for compensation has... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Council member compensation....

  19. 20 CFR 404.971 - Dismissal by Appeals Council.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Dismissal by Appeals Council. 404.971 Section 404.971 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... Decisions Appeals Council Review § 404.971 Dismissal by Appeals Council. The Appeals Council will...

  20. 76 FR 7823 - New England Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-02-11

    ... National Oceanic and Atmospheric Administration RIN 0648-XA208 New England Fishery Management Council... (NEFSC), in cooperation with the New England Fishery Management Council (Council) will convene a webinar..., Executive Director, New England Fishery Management Council; telephone: (978) 465-0492....