WorldWideScience

Sample records for cos chinese optical society

  1. Sixty years of the Chinese physical society

    International Nuclear Information System (INIS)

    Qian Linzhao; Wu Ziqin; Li Shounan.

    1993-01-01

    In commemoration of the 60th anniversary of the Chinese Physical Society (CPS) established in 1932, an overview is presented of the activities in the former fifty years. The main achievements of physics research in China, the progress in research and development in various branches of physics and the activities of the CPS over the last ten years are then reviewed

  2. The Applicability of Western Socio-Legal Frameworks to the Study of Negotiation in Chinese Society

    Science.gov (United States)

    Chung, Mona; Ingleby, Richard

    2011-01-01

    Theoretical frameworks for the examination of negotiation generated by Western academics do not easily translate to Chinese society because of fundamental differences between Western and Chinese society. Attempts to study negotiation in Chinese society and to improve negotiation between Chinese and Western business people are themselves…

  3. Hainan - State, Society, and Business in a Chinese Province

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    studies: central-local relations, institutional reform, state-society relations, and economic development strategies. It provides detailed evidence of how relations between party cadres, state bureaucrats, businesses, foreign investors and civil society play out in practice in China today. It argues...... of an economic, political, and social nature that have received great attention from Beijing, in particular the "small government, big society" project. This book provides a full account of this transition, showing how Hainan casts important light on a number of highly topical issues in contemporary China...... that despite the liberalization of recent years, especially in the economic sphere, the party state remains the most powerful actor in Chinese society, and that path-breaking reform experiments such as in Hainan remain highly vulnerable due to the central government's hesitation to commit the resources...

  4. Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis.

    Science.gov (United States)

    Bankaitis, Katherine; Borriello, Lucia; Cox, Thomas; Lynch, Conor; Zijlstra, Andries; Fingleton, Barbara; Gužvić, Miodrag; Anderson, Robin; Neman, Josh

    2017-04-01

    During September 16th-20th 2016, metastasis experts from around the world convened for the 16th Biennial Congress of the Metastasis Research Society and 12th National Congress of the Chinese Tumor Metastasis Society in Chengdu, China to share most current data covering basic, translational, and clinical metastasis research. Presentations of the more than 40 invited speakers of the main congress and presentations from the associated Young Investigator Satellite Meeting are summarized in this report by session topic. The congress program also included three concurrent short talk sessions, an advocacy forum with Chinese and American metastatic patient advocates, a 'Meet the Professors Roundtable' session for young investigators, and a 'Meet the Editors' session with editors from Cancer Cell and Nature Cell Biology. The goal of integrating expertise and exchanging the latest findings, ideas, and practices in cancer metastasis research was achieved magnificently, thanks to the excellent contributions of many leaders in the field.

  5. The research infrastructure of Chinese foundations, a database for Chinese civil society studies.

    Science.gov (United States)

    Ma, Ji; Wang, Qun; Dong, Chao; Li, Huafang

    2017-07-25

    This paper provides technical details and user guidance on the Research Infrastructure of Chinese Foundations (RICF), a database of Chinese foundations, civil society, and social development in general. The structure of the RICF is deliberately designed and normalized according to the Three Normal Forms. The database schema consists of three major themes: foundations' basic organizational profile (i.e., basic profile, board member, supervisor, staff, and related party tables), program information (i.e., program information, major program, program relationship, and major recipient tables), and financial information (i.e., financial position, financial activities, cash flow, activity overview, and large donation tables). The RICF's data quality can be measured by four criteria: data source reputation and credibility, completeness, accuracy, and timeliness. Data records are properly versioned, allowing verification and replication for research purposes.

  6. Responses of Chinese Higher Education to the Information Society

    Science.gov (United States)

    Cai, Yuzhuo; Guo, Wenge

    2006-01-01

    Compared to the advanced industrial countries, the use of information technology in Chinese higher education came relatively late. Nevertheless, recent Chinese practices have achieved significant progress in the country's efforts to bridge the digital divide. This article focuses special attention on the responses of Chinese higher education to…

  7. The adaptation of Chinese adolescents in two societies: a comparison of Chinese adolescents in Hong Kong and Australia.

    Science.gov (United States)

    Leung, Cynthia; Karnilowicz, Wally

    2009-06-01

    This study aimed to compare the adaptation of two groups of migrant Chinese adolescents with their nonmigrant peers. The migrant adolescents included 55 Chinese migrant adolescents who migrated to Australia (Chinese-Australian) and 111 China-born adolescents who migrated to Hong Kong (Chinese-Hong Kong). The nonmigrant adolescents included 157 Anglo-Australian adolescents residing in Australia and 456 Hong Kong-born Chinese adolescents residing in Hong Kong. There were three research questions in this study. First, would there be any differences in the adaptation of Chinese migrant adolescents in different societies of settlement? Second, would migrant adolescents experience more adaptation problems than nonmigrant adolescents? Third, would there be any differences in the adaptation of adolescents in the two societies, Australia and Hong Kong? It was hypothesized that: (1) mainland Chinese migrant adolescents in Hong Kong would experience more adaptation problems than Chinese migrant adolescents in Australia; (2) migrant adolescents would report better adaptation than nonmigrant adolescents; (3) adolescents in Hong Kong would report poorer adaptation than adolescents in Australia. The participants were requested to complete a questionnaire on various adaptation outcome measures including life satisfaction, self-esteem, psychological symptoms, academic satisfaction, and behaviour problems. The results indicated that Chinese-Australian adolescents reported better psychological adaptation but Chinese-Hong Kong adolescents reported better sociocultural adaptation. Adolescents resident in Australia reported higher psychological adaptation but lower sociocultural adaptation than those in Hong Kong. Migrant adolescents reported better psychological and sociocultural adaptation than their nonmigrant counterparts. The results were discussed in relation to the social and educational systems of the two societies.

  8. Chinese National Optical Education Small Private Online Course system

    Science.gov (United States)

    Zhang, XiaoJie; Lin, YuanFang; Liu, Xu; Liu, XiangDong; Cen, ZhaoFeng; Li, XiaoTong; Zheng, XiaoDong; Wang, XiaoPing

    2017-08-01

    In order to realize the sharing of high quality course resources and promote the deep integration of `Internet+' higher education and talent training, a new on-line to off-line specialized courses teaching mode was explored in Chinese colleges and universities, which emphasized different teaching places, being organized asynchronously and localized. The latest progress of the Chinese National Optical Education Small Private On-line Course (CNOESPOC) system set up by Zhejiang University and other colleges and universities having disciplines in the field of optics and photonics under the guidance of the Chinese National Steering Committee of Optics and Photonics (CNSCOP) was introduced in this paper. The On-line to Off-line (O2O) optical education teaching resource sharing practice offers a new good example for higher education in China under the background of Internet +.

  9. Hainan - State, Society, and Business in a Chinese Province

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    studies: central-local relations, institutional reform, state-society relations, and economic development strategies. It provides detailed evidence of how relations between party cadres, state bureaucrats, businesses, foreign investors and civil society play out in practice in China today. It argues......This book examines the complex relationship between the state, society and business in China, focusing on the experience of the island province of Hainan. This island, for many years a provincial backwater, was given provincial rank in 1988 and became the testing ground for experiments...

  10. The role of NGO in nuclear public communication and the practices of the Chinese Nuclear Society

    International Nuclear Information System (INIS)

    Shen, L.

    2014-01-01

    'Full text:' Public acceptance is becoming an outstanding issue in China's nuclear power development. All the related stakeholders have been working hard to improve their work on public communication. This paper started with a general view of the nuclear power in China and then presented the situation on nuclear public acceptance, the related laws and regulations in China. After that, the paper discussed the four advantages of NGOs such as nuclear societies in this course. The paper presented more on the practices of Chinese Nuclear Society in public communication and nuclear science popularization.It is concluded with some suggestions for public communication. (author)

  11. The role of NGO in nuclear public communication and the practices of the Chinese Nuclear Society

    Energy Technology Data Exchange (ETDEWEB)

    Shen, L., E-mail: shenlx@cnnc.com.cn [Chinese Nuclear Society, Beijing (China)

    2014-07-01

    'Full text:' Public acceptance is becoming an outstanding issue in China's nuclear power development. All the related stakeholders have been working hard to improve their work on public communication. This paper started with a general view of the nuclear power in China and then presented the situation on nuclear public acceptance, the related laws and regulations in China. After that, the paper discussed the four advantages of NGOs such as nuclear societies in this course. The paper presented more on the practices of Chinese Nuclear Society in public communication and nuclear science popularization.It is concluded with some suggestions for public communication. (author)

  12. The role of Chinese National Steering Committee of Optics and Photonics (CNSCOP)

    Science.gov (United States)

    Liu, Xu; Ge, Baozhen; Qin, Shiqiao; Liu, Xiangdong; Zhang, Xiaojie; Shi, Yaocheng

    2017-08-01

    The Chinese National Steering Committee of Optics and Photonics (CNSCOP) is appointed by the ministry of education of China. The members of the committee are selected from 18 representative domestic Universities, 4 Chinese Academic Institutes and major enterprises. Through designing National high education standards for optic and Photonics; establishing Teacher's training Center; Organizing National annual conference on Optics and Photonics education; setting up the Optics and Photonics Teaching Resource Sharing Platform etc., the CNSCOP has developed many process in order to improve the Chinese optical education quality and to promote the high achievements of students for whole country. In this paper, we will give brief introduction of all these activities.

  13. Local engagement of Chinese international students in host societies: a perspective of diasporic Chinese community building (CCB) in the UK

    OpenAIRE

    Wu, Bin

    2016-01-01

    Social changes in diasporic Chinese communities in the 21st century calls for a new approach to understand new dynamics, resources and opportunities to bring together all stakeholders, both Chinese and non-Chinese, toward mutual trust, effective communication and collaboration in host countries (Wu, 2010; 2011). For this purpose, this paper aims to develop a framework for the process of diasporic Chinese community building (CCB) in general and for the local engagement of Chinese international...

  14. New era of the relationship between Chinese interventional radiology sub-society and journal of interventional radiology

    International Nuclear Information System (INIS)

    Li Linsun

    2009-01-01

    The past decades have witnessed interventional radiology in China to go from a very initial clinical practice to an important medical player in modern medicine. Recently, a friendly collaboration has been successfully established between the Chinese Interventional Radiology Sub-society and the Journal of Interventional Radiology. The Chinese Interventional Radiology Sub-society will take the full responsibility for the academic governance of the Journal of Interventional Radiology and the Journal of Interventional Radiology will formally become the sole interventional academic periodical of the Chinese Interventional Radiology Sub-society in China. This collaboration will surely make Chinese interventional radiology to initiate a new era,promote the further development of interventional radiology at home and enable the Journal of Interventional Radiology to step into the international medical circle. (authors)

  15. Constructing library networks with Chinese characteristics: bringing about society-wide sharing of information resources

    Directory of Open Access Journals (Sweden)

    Salman Nazari

    2006-10-01

    Full Text Available As one of the most important components of a nations basic facilities, the networking of the library plays a vital role in terms of promoting the sharing of access to information. Although the traditional methods of literature indexing and accessing will continue to exist and develop, library networking will become the new model and the direction for the development of the library. Through the discussion of the current situation of information sharing in the Chinese library, the author analyzes the factors that affect information sharing and proposes establishing a cooperative networking center for regional libraries in one region by linking together dispersed information and assembling an open, shared repository of information resources, which will promote literature resources sharing throughout society.  

  16. College Students' Definitions of Intimate Partner Violence: A Comparative Study of Three Chinese Societies.

    Science.gov (United States)

    Jiao, Yanpeng; Sun, Ivan Y; Farmer, Ashley K; Lin, Kai

    2016-04-01

    Although a large number of studies have been conducted worldwide to examine various aspects of intimate partner violence (IPV), comparative study of people's views on such violence in Chinese societies has been scarce. Using survey data collected from more than 850 college students in China, Hong Kong, and Taiwan, this study specifically assessed the impact of attitudes toward gender role and violence, personal and vicarious experience, demographic characteristics, and locality on students' definitions of IPV. The Taiwanese students were most likely to define a broader range of abusive behavior as IPV, followed by Hong Kong and Beijing students. Gender role and violence attitudes appeared to be most important predictors of IPV definitions. College students who supported the notion of male dominance were more likely to have a narrower definition of IPV, whereas those who viewed domestic violence as crime were more inclined to have a broader definition of IPV. Implications for future research and policy were discussed. © The Author(s) 2014.

  17. Formulation of Policy and Strategy in Developing Creativity Education in Four Asian Chinese Societies: A Policy Analysis

    Science.gov (United States)

    Hui, Anna N. N.; Lau, Sing

    2010-01-01

    The present study sought to compare and contrast educational policies on creativity education in four Asian Chinese societies, namely mainland China, Hong Kong, Singapore, and Taiwan. It establishes five criteria on creativity education policy, including policies regarding legislation on creativity education, definitions of creativity, standard…

  18. Cycle 24 COS/NUV Fold Distribution

    Science.gov (United States)

    Wheeler, Thomas; Welty, Alan

    2018-02-01

    We summarize the Cycle 24 COS/NUV Fold Distribution for the Cosmic Origins Spectrograph's (COS) MAMA detector on the Hubble Space Telescope. The detector micro-channel plate's health state is determined and the results presented.

  19. Chinese vinegar classification via volatiles using long-optical-path infrared spectroscopy and chemometrics.

    Science.gov (United States)

    Dong, D; Zheng, W; Jiao, L; Lang, Y; Zhao, X

    2016-03-01

    Different brands of Chinese vinegar are similar in appearance, color and aroma, making their discrimination difficult. The compositions and concentrations of the volatiles released from different vinegars vary by raw material and brewing process and thus offer a means to discriminate vinegars. In this study, we enhanced the detection sensitivity of the infrared spectrometer by extending its optical path. We measured the infrared spectra of the volatiles from 5 brands of Chinese vinegar and observed the spectral characteristics corresponding to alcohols, esters, acids, furfural, etc. Different brands of Chinese vinegar had obviously different infrared spectra and could be classified through chemometrics analysis. Furthermore, we established classification models and demonstrated their effectiveness for classifying different brands of vinegar. This study demonstrates that long-optical-path infrared spectroscopy has the ability to discriminate Chinese vinegars with the advantages that it is fast and non-destructive and eliminates the need for sampling. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Politics, Economics, Society, and Overseas Chinese Teaching: A Case Study of Australia

    Science.gov (United States)

    Chen, Ping

    2016-01-01

    The history and current state of Chinese teaching in Australia has largely been determined by two key factors: first, the country's policy on languages, and in particular its policy regarding foreign language education; and second, its immigrants and overseas students from Chinese-speaking countries and regions. Beginning in the 1980s, Chinese…

  1. Legislating separation and solidarity in plural societies: the Chinese in Indonesia and Malaysia.

    Science.gov (United States)

    Hwang, Julie Chernov; Sadiq, Kamal

    2010-01-01

    The Chinese minority plays a dominant role in the economies of Indonesia and Malaysia, a fact that evokes indigenous resentment. However, Indonesia and Malaysia dealt differently with the issue. Malaysia legislated the Malays into the economy and protected Chinese citizenship, making them an integral part of a multicultural state. By contrast, New Order Indonesia adopted policies of economic manipulation, forced assimilation, and unequal citizenship. Only when the New Order regime fell did Chinese integration begin. The policy trajectories of Indonesia and Malaysia offer important lessons for plural states.

  2. Reliability and concurrent validity of the adapted Chinese version of Scoliosis Research Society-22 (SRS-22) questionnaire.

    Science.gov (United States)

    Cheung, Kenneth M C; Senkoylu, Alpaslan; Alanay, Ahmet; Genc, Yasemin; Lau, Sarah; Luk, Keith D

    2007-05-01

    Validation study to define validity and reliability of an adapted and translated questionnaire. Assessment of the concurrent validity and reliability of a Chinese version of SRS-22 outcome instrument. No valid health-related quality of life (HRQL) outcome instrument exists for patients with spinal deformity in Chinese. The modified SRS-22 questionnaire was proven to be an appropriate outcome instrument in English, and has already been translated and validated in several other languages. The English version of the SRS-22 questionnaire was adapted to Chinese according to the International Quality of Life Assessment Project guidelines. To assess reliability, 48 subjects with adolescent idiopathic scoliosis (mean age, 16.5 years) filled the questionnaire on 2 separate occasions (Group 1). To assess concurrent validity, 50 subjects (mean age, 21 years) filled in the same questionnaire and a previously validated Chinese version of the Short Form-36 (SF36) questionnaire (Group 2). Internal consistency, reproducibility and concurrent validity were determined with Cronbach's alpha coefficient, interclass correlation coefficient and Pearson correlation coefficient, respectively. Cronbach's alpha coefficient for the 4 major domains (function/activity, pain, self-image/appearance and mental health) were high. Intraclass correlation was also excellent for all domains. For concurrent validity, excellent correlation was found in 1 domain, good in 12 domains, moderate in 3 domains, and poor in 1 domain of the 17 relevant domains. Both cultural adaptation and linguistic translation are essential in any attempt to use a HRQL questionnaire across cultures. The Chinese version of the SRS-22 outcome instrument has satisfactory internal consistency and excellent reproducibility. It is ready for use in clinical studies on idiopathic scoliosis in Chinese-speaking societies.

  3. The Optical Society's 2016 topical meeting on optical interference coatings: introduction.

    Science.gov (United States)

    Ristau, Detlev; Li, Li; Sargent, Robert; Sytchkova, Anna

    2017-02-01

    This feature issue of Applied Optics is dedicated to the 13th Topical Meeting on Optical Interference Coatings, which was held June 19-24, 2016, in Tucson, Arizona, USA. The conference, taking place every three years, is a focal point for global technical interchange in the field of optical interference coatings and provides premier opportunities for people working in the field to present their new advances in research and development. Papers presented at the meeting covered a broad range of topics, including fundamental research on coating design theory, new materials, and deposition and characterization technologies, as well as the vast and growing number of applications in electronic displays, communication, optical instruments, high power and ultra-fast lasers, solar cells, space missions, gravitational wave detection, and many others.

  4. Optical mapping of brain activation during the English to Chinese and Chinese to English sight translation.

    Science.gov (United States)

    He, Yan; Wang, Meng-Yun; Li, Defeng; Yuan, Zhen

    2017-12-01

    Translating from Chinese into another language or vice versa is becoming a widespread phenomenon. However, current neuroimaging studies are insufficient to reveal the neural mechanism underlying translation asymmetry during Chinese/English sight translation. In this study, functional near infrared spectroscopy (fNIRS) was used to extract the brain activation patterns associated with Chinese/English sight translation. Eleven unbalanced Chinese (L1)/English (L2) bilinguals participated in this study based on an intra-group experimental design, in which two translation and two reading aloud tasks were administered: forward translation (from L1 to L2), backward translation (from L2 to L1), L1 reading, and L2 reading. As predicted, our findings revealed that forward translation elicited more pronounced brain activation in Broca's area, suggesting that neural correlates of translation vary according to the direction of translation. Additionally, significant brain activation in the left PFC was involved in backward translation, indicating the importance of this brain region during the translation process. The identical activation patterns could not be discovered in forward translation, indicating the cognitive processing of reading logographic languages (i.e. Chinese) might recruit incongruent brain regions.

  5. The CzeCOS Network

    Science.gov (United States)

    Havránková, Kateřina; Taufarová, Klára; Šigut, Ladislav; McGloin, Ryan; Acosta, Manuel; Dušek, Jiří; Krupková, Lenka; Macálková-Mžourková, Lenka; Pavelka, Marian; Dařenová, Eva; Yadav, Shilpi; Nguyen, Vinh; Guerra, Carlos; Janous, Dalibor; Marek, Michal V.

    2017-04-01

    The Global Change Research Institute of the Czech Academy of Sciences (CzechGlobe) have established a well-equipped network of ecosystem stations, with modern instrumentation for eco-physiological, plant physiological and micrometeorological studies, and estimation of GHG emissions. The network of stations (CzeCOS) covers the main terrestrial ecosystems of the Czech Republic (young and old coniferous forest, deciduous forest, mixed floodplain forest, grassland, wetland and cropland). The ecosystem stations are equipped with eddy covariance systems, soil and stem chamber systems for CO2 efflux and instruments for making micrometeorological measurements. The network enables detailed research to be conducted on topics such as: the carbon balance of different ecosystems, energy balance closure, the impact of current climate conditions on production and ecosystem disturbances during extreme weather conditions (drought, floods, winter storms, etc.) at regional, national and international scales. As a part of global networks (Fluxnet, ANAEe, ICOS), CzeCOS participates in evaluating and predicting environmental change and helps in the proposal of mitigation measures. Another important issue studied at some of the CzeCOS sites is the use of the eddy covariance method in sloping terrain in order to improve eddy covariance data processing for sites in this kind of terrain. Here we show specific results from the sites and outline the importance of the regional/national network for improving our knowledge about the exchange of matter and energy fluxes at different ecosystems. This study was supported by the Ministry of Education, Youth and Sports of CR within the National Sustainability Program I (NPU I), grant number LO1415 and LD 15040. Computational resources were provided by the CESNET LM2015042 and the CERIT Scientific Cloud LM2015085, provided under the programme "Projects of Large Research, Development, and Innovations Infrastructures".

  6. Understanding and Preventing Financial Fraud Against Older Citizens in Chinese Society: Results of a Focus Group Study.

    Science.gov (United States)

    Li, Jessica C M; Yu Yolanda, Mengyan; Wong, Gabriel T W; Ngan, Raymond M H

    2016-10-01

    This study examines the public discourse on financial fraud against older citizens in Chinese society using six focus groups with 45 stakeholders comprising social workers, police officers, caregivers, nurses, community representatives, and insurance and banking personnel. This study uses qualitative data to describe the patterns and social features that facilitate this specific type of crime in Hong Kong. The narratives of the community stakeholders reveal several specific social features of Hong Kong that contribute to financial fraud against older persons, such as traditional Chinese values and ideologies, increasing cross-border activities, the Internet and technological advancements, and unfavourable economic situations. The results of this study support the assumptions of the routine activity approach and have a number of theoretical and practical implications. © The Author(s) 2015.

  7. Immigrant Chinese Mothers' Socialization of Achievement in Children: A Strategic Adaptation to the Host Society

    Science.gov (United States)

    Ng, Florrie Fei-Yin; Sze, Irene Nga-Lam; Tamis-LeMonda, Catherine S.; Ruble, Diane N.

    2017-01-01

    Academic socialization by low-income immigrant mothers from Mainland China was investigated in two studies. Immigrant Chinese mothers of first graders (n = 52; M[subscript age] = 38.69) in the United States (Study 1) and kindergartners (n = 86; M[subscript age] = 36.81) in Hong Kong (Study 2) tell stories that emphasized achieving the best grade…

  8. Review the past and look forward the future: in celebration of 20 anniversary of(Chinese Society of Interventional Radiology)

    International Nuclear Information System (INIS)

    Li Linsun

    2010-01-01

    This paper aims to make a brief review of the Chinese Society of Interventional Radiology in the past 20 years since it was established and to put forward some personal suggestions. The article will mainly describe the following contents: (1) to make suggestions to set up a standard organization of Chinese Interventional Society; (2) to demand interventional radiologist to be a real clinical doctor, to take care of their own patients for full course, to practice all kinds of minimally-invasive therapy; (3) to improve the ability of scientific research work; (4) to perfect the system of education, training and promotion in interventional radiology field; (5) to strengthen the special team of interventional radiologists; (6) to raise the academic level and status of the 'Journal of Interventional Radiology'; (7) to heighten the quality of academic activity and to intensify the organization system of interventional discipline; (8) to correctly deal with the competition between different subjects; and (9) to improve and perfect our own interventional job.(authors)

  9. Social sustainability in an ageing chinese society : Towards an integrative conceptual framework

    NARCIS (Netherlands)

    Liu, Yafei; Dijst, Martin; Geertman, Stan; Cui, Can

    2017-01-01

    Social sustainability is a relatively underexposed dimension of the sustainability debate. Diversified and discipline-specific study perspectives and the lack of contextualization make it difficult to gain a comprehensive understanding of social sustainability in non-Western societies. In examining

  10. Ethnic Contestation and Language Policy in a Plural Society: The Chinese Language Movement in Malaysia, 1952-1967

    Science.gov (United States)

    Yao Sua, Tan; Hooi See, Teoh

    2014-01-01

    The Chinese language movement was launched by the Chinese educationists to demand the recognition of Chinese as an official language to legitimise the status of Chinese education in the national education system in Malaysia. It began in 1952 as a response to the British attempt to establish national primary schools teaching in English and Malay to…

  11. Resource analysis of the Chinese society 1980-2002 based on exergy-Part 3: Agricultural products

    International Nuclear Information System (INIS)

    Chen, B.; Chen, G.Q.

    2007-01-01

    This part is the continuation of the second part on renewable energy sources and forest. The major agricultural products entering the Chinese society from 1980 to 2002 are calculated and analyzed in detail in this paper. The relative political infrastructure and organization of the agricultural production in the rural areas frequently and rapidly changed during the past two decades, making profound impact on the crop structure and yields. The planning and organization of agriculture has been adjusted when prices and market are introduced into agricultural production and the direct planning is restricted. The growth in usage of fertilizers, pesticides and farm-use plastic membrane is revealed. The state farm system as the pioneer of exploring the modernization of agriculture and accumulating experiences is also described

  12. Cycle 24 COS FUV Dark Monitor Summary

    Science.gov (United States)

    Fix, Mees B.

    2018-02-01

    We summarize the Cycle 24 FUV Dark Monitoring Program for COS, covering the dates from November 2016 to October 2017. We give an overview of the calibration plan and summary for this calibration program.

  13. In-Law and Mate Preferences in Chinese Society and the Role of Traditional Cultural Values.

    Science.gov (United States)

    Guo, Qingke; Li, Yujie; Yu, Shushuang

    2017-01-01

    Using 347 parent-child dyads as participants, this study directly examined in-law and mate preferences in a typical collectivist culture. The results showed (1) traits indicating social status and parental investment were more highly valued by the parents, while traits indicating genetic quality and traits related to romantic love were more highly valued by the children. (2) Parental preferences were moderated by gender of the in-laws. Good earning capacity was more preferred by parents in a son-in-law, traits connoting genetic quality and reproductive fitness were more preferred by parents in a daughter-in-law. (3) There was more convergence in in-law and mate preferences in Chinese culture than in Western cultures. (4) Traditional cultural values (i.e., filial piety) can be used as a predictor of traditional mate preferences and less parent-child divergences. Additionally, greater preference for kind and understanding by parents than by children as well as by daughters than by sons, and greater preference for social status by the daughters' than by the sons' parents have not been observed in the rating and the ranking instrument. These findings illustrated how culture handles the parent-child disagreement over mating by authorizing greater parental influence on children's mating decisions.

  14. Analysis of Society Conditions/Reality During Chinese Feudal Era in the Novel Liaozhai Zhiyi

    Directory of Open Access Journals (Sweden)

    Chen Chongjie

    2010-11-01

    Full Text Available Liaozhai Zhiyi is a compilation of short stories created by the Qing Dynasty novelist, Pu Songling. The main concept is not centered on regular ghost stories, but the author told a story on real life and the fantasy world by describing realities of society life in the feudal era. The author, through stories in Liaozhai Zhiyi, analyses social reality in their education, politics, love, economic and moral aspects. The author of Liaozhai Zhiyi uses of a lot of stories concerning fox spirits, ghosts, and other types of spirits in portraying his critics and anger towards incidents happening in feudal China. Analysis shows that Liaozhai Zhiyi broadly depicts social reality happening in feudal era in education, politics, love, economic and moral aspects. Liaozhai Zhiyi also criticizes the corrupt government official examination scheme, and the crime and decadence of the feudal government. In contrast, the stories also praised the freedom of young men and women seeking love in marriage, endorsing young men and women to reject arranged marriages, showing women in the economic independence and social advancement, and summed up the lessons of social life.

  15. A method of neighbor classes based SVM classification for optical printed Chinese character recognition.

    Science.gov (United States)

    Zhang, Jie; Wu, Xiaohong; Yu, Yanmei; Luo, Daisheng

    2013-01-01

    In optical printed Chinese character recognition (OPCCR), many classifiers have been proposed for the recognition. Among the classifiers, support vector machine (SVM) might be the best classifier. However, SVM is a classifier for two classes. When it is used for multi-classes in OPCCR, its computation is time-consuming. Thus, we propose a neighbor classes based SVM (NC-SVM) to reduce the computation consumption of SVM. Experiments of NC-SVM classification for OPCCR have been done. The results of the experiments have shown that the NC-SVM we proposed can effectively reduce the computation time in OPCCR.

  16. A method of neighbor classes based SVM classification for optical printed Chinese character recognition.

    Directory of Open Access Journals (Sweden)

    Jie Zhang

    Full Text Available In optical printed Chinese character recognition (OPCCR, many classifiers have been proposed for the recognition. Among the classifiers, support vector machine (SVM might be the best classifier. However, SVM is a classifier for two classes. When it is used for multi-classes in OPCCR, its computation is time-consuming. Thus, we propose a neighbor classes based SVM (NC-SVM to reduce the computation consumption of SVM. Experiments of NC-SVM classification for OPCCR have been done. The results of the experiments have shown that the NC-SVM we proposed can effectively reduce the computation time in OPCCR.

  17. An autopsy of dead planetary systems with COS

    Science.gov (United States)

    Debes, John

    2014-10-01

    We propose to use HST/COS to conduct autopsies of dead planetary systems around UV bright hydrogen-white dwarfs (WDs), which have dust disks found via their mid-IR emission in excess of that expected from the photosphere. As part of a WISE survey, and followed up with a combination of NASA Keck HIRES/Magellan MIKE optical spectroscopy, we have identified three new systems that are accreting dust. These WDs are bright in the mid-IR and UV, gold-standard targets for studies with HST/COS and later with JWST. The dusty material is debris resulting from the tidal disruption of exo-asteroids that accrete onto the WD surface. Many atomic elements from the accreted and dissociated dust particles are detectable with COS, enabling abundance determinations of exo-asteroidal material. Moreover, the photospheric abundances of this material can be directly compared with a determination of the dust mineralogy obtained with future JWST mid-IR spectroscopy-our proposed UV observations provide complementary constraints on mineralogical compositions of the accreting dust particles. UV spectroscopy is crucial for cataloging elemental abundances for these exo-asteroids. For the majority of WDs, optical spectroscopy reveals only a couple of lines of Ca or Mg, while UV spectroscopy captures lines from Al, Fe, Si, C, Ni, O, S, Cr, P, and Ti. Obtaining the elemental abundances of exo-asteroids is comparable to the spectroscopic characterization of transiting exoplanets or protoplanetary disks-all of these techniques determine how the chemical diversity of planetary systems translate into planetary architectures and the probability of habitable planets around solar-type stars.

  18. Clinical evaluation and mitochondrial DNA sequence analysis in three Chinese families with Leber's hereditary optic neuropathy

    International Nuclear Information System (INIS)

    Qian Yaping; Zhou Xiangtian; Hu Yongwu; Tong Yi; Li Ronghua; Lu Fan; Yang Huanming; Mo Junqin; Qu Jia; Guan Minxin

    2005-01-01

    We report here the clinical, genetic, and molecular characterization of three Chinese families (WZ4, WZ5, and WZ6) with Leber's hereditary optic neuropathy (LHON). Clinical and genetic evaluations revealed the variable severity and age-of-onset in visual impairment in these families. Penetrances of visual impairment in these Chinese families were 33.3%, 35.7%, and 35.5%, respectively, with an average 34.8%. Furthermore, the average age-at-onset in those Chinese families was 17, 20, and 18 years. In addition, the ratios between affected male and female matrilineal relatives in these Chinese families were 3:0, 1:1, and 1.2:1, respectively. Sequence analysis of the complete mitochondrial genomes in these pedigrees showed the distinct sets of mtDNA polymorphism, in addition to the identical G11778A mutation associated with LHON in many families. The fact that mtDNA of those pedigrees belonged to different haplogroups F1, D4, and M10 suggested that the G11778A mutation occurred sporadically and multiplied through evolution of the mtDNA in China. However, there was the absence of functionally significant mutations in tRNA and rRNAs or secondary LHON mutations in these Chinese families. The I187T mutation in the ND1, the S99A mutation in the A6, the V254I in CO3, and I58V in ND6 mutation, showing high evolutional conservation, may contribute to the phenotypic expression of the G11778A mutation in the WZ6 pedigree. By contrast, none of mtDNA variants are evolutionarily conserved and implicated to have significantly functional consequence in WZ4 and WZ5 pedigrees. Apparently, these variants do not have a potential modifying role in the development of visual impairment associated with G11778A mutation in those two families. Thus, nuclear modifier gene(s) or environmental factor(s) seem to account for the penetrance and expressivity of LHON in these three Chinese families carrying the G11778A mutation

  19. Proceedings of the IEEE laser and electro-optics society annual meeting

    International Nuclear Information System (INIS)

    Hudson, M.J.B.; Raney, H.; Raney, D.; Spalaris, C.N.

    1990-01-01

    This book is covered under the following headings: Electro-optic systems; Emerging laser technology; Optical sensors and measurements; Optoelectronics; Semiconductor diode lasers; Solid state lasers; UV and short wavelength; Applied optical diagnostics of semiconductor materials and devices symposium and optical sensors and measurements; and Applied optical diagnostics of semiconductor materials and devices symposium

  20. Solution structure of the microtubule-targeting COS domain of MID1.

    Science.gov (United States)

    Wright, Katharine M; Du, Haijuan; Dagnachew, Mesgana; Massiah, Michael A

    2016-08-01

    The human MID1 protein is required for the proper development during embryogenesis. Mutations of MID1 are associated with X-linked Opitz G syndrome, characterized by midline anomalies. MID1 associates with the microtubules and functions as an ubiquitin E3 ligase, targeting protein phosphatase 2A for ubiquitin-mediated regulation. The mechanism of microtubule association is not known. Recently, a 60-amino acid region termed the C-terminal subgroup One Signature (COS) box/domain was identified at the C-terminal end of the coiled-coil (CC) domain that facilitates microtubule localization. Insertion of the MID1 COS domain at the C-terminal end of the CC domain of a nonmicrotubule-associated TRIM protein confers microtubule localization. Here, we report the solution structure of the COS domain of MID1. The domain adopts a helix-loop-helix structure in which the N- and C-terminal ends are in close proximity. Hydrophobic residues stabilizing the interaction of the two α-helices form a central hydrophobic core. The loop separating the α-helices is structured, with two of its hydrophobic residues making contact with the central core. On the outer surface, positively charged residues form a distinct basic patch near the termini that we postulate is important for microtubule binding. A model of the structure of the preceding coiled-coil and COS domains (CC-COS) show that the COS domain forms a helical bundle at the C-terminal end of the CC domain similar to the spectrin-like fold observed with some known microtubule-binding proteins. Interestingly, the CC-COS domains bind to microtubules, demonstrating for the first time that MID1 can directly associate with the microtubules. Structural data are available in PDB database under the accession number 5IM8. © 2016 Federation of European Biochemical Societies.

  1. A novel OPA1 mutation in a Chinese family with autosomal dominant optic atrophy

    International Nuclear Information System (INIS)

    Zhang, Juanjuan; Yuan, Yimin; Lin, Bing; Feng, Hao; Li, Yan; Dai, Xianning; Zhou, Huihui; Dong, Xujie; Liu, Xiao-Ling; Guan, Min-Xin

    2012-01-01

    Highlights: ► We report the characterization of a four-generation large Chinese family with ADOA. ► We find a new heterozygous mutation c.C1198G in OPA1 gene which may be a novel pathogenic mutation in this pedigree. ► We do not find any mitochondrial DNA mutations associated with optic atrophy. ► Other factors may also contribute to the phenotypic variability of ADOA in this pedigree. -- Abstract: A large four-generation Chinese family with autosomal dominant optic atrophy (ADOA) was investigated in the present study. Eight of the family members were affected in this pedigree. The affected family members exhibited early-onset and progressive visual impairment, resulting in mild to profound loss of visual acuity. The average age-at-onset was 15.9 years. A new heterozygous mutation c.C1198G was identified by sequence analysis of the 12th exon of the OPA1 gene. This mutation resulted in a proline to alanine substitution at codon 400, which was located in an evolutionarily conserved region. This missense mutation in the GTPase domain was supposed to result in a loss of function for the encoded protein and act through a dominant negative effect. No other mutations associated with optic atrophy were found in our present study. The c.C1198G heterozygous mutation in the OPA1 gene may be a novel key pathogenic mutation in this pedigree with ADOA. Furthermore, additional nuclear modifier genes, environmental factors, and psychological factors may also contribute to the phenotypic variability of ADOA in this pedigree.

  2. A novel OPA1 mutation in a Chinese family with autosomal dominant optic atrophy

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Juanjuan; Yuan, Yimin; Lin, Bing; Feng, Hao; Li, Yan [School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou 325027, Zhejiang (China); Dai, Xianning; Zhou, Huihui [Attardi Institute of Mitochondrial Biomedicine and Zhejiang Provincial Key Laboratory of Medical Genetics, School of Life Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang (China); Dong, Xujie [School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou 325027, Zhejiang (China); Liu, Xiao-Ling, E-mail: lxl@mail.eye.ac.cn [School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou 325027, Zhejiang (China); Guan, Min-Xin, E-mail: min-xin.guan@cchmc.org [Attardi Institute of Mitochondrial Biomedicine and Zhejiang Provincial Key Laboratory of Medical Genetics, School of Life Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang (China); Institute of Genetics, Zhejiang University, Hangzhou, Zhejiang 310012 (China); Division of Human Genetics, Cincinnati Children' s Hospital Medical Center, OH 45229 (United States)

    2012-03-23

    Highlights: Black-Right-Pointing-Pointer We report the characterization of a four-generation large Chinese family with ADOA. Black-Right-Pointing-Pointer We find a new heterozygous mutation c.C1198G in OPA1 gene which may be a novel pathogenic mutation in this pedigree. Black-Right-Pointing-Pointer We do not find any mitochondrial DNA mutations associated with optic atrophy. Black-Right-Pointing-Pointer Other factors may also contribute to the phenotypic variability of ADOA in this pedigree. -- Abstract: A large four-generation Chinese family with autosomal dominant optic atrophy (ADOA) was investigated in the present study. Eight of the family members were affected in this pedigree. The affected family members exhibited early-onset and progressive visual impairment, resulting in mild to profound loss of visual acuity. The average age-at-onset was 15.9 years. A new heterozygous mutation c.C1198G was identified by sequence analysis of the 12th exon of the OPA1 gene. This mutation resulted in a proline to alanine substitution at codon 400, which was located in an evolutionarily conserved region. This missense mutation in the GTPase domain was supposed to result in a loss of function for the encoded protein and act through a dominant negative effect. No other mutations associated with optic atrophy were found in our present study. The c.C1198G heterozygous mutation in the OPA1 gene may be a novel key pathogenic mutation in this pedigree with ADOA. Furthermore, additional nuclear modifier genes, environmental factors, and psychological factors may also contribute to the phenotypic variability of ADOA in this pedigree.

  3. Hubble COS Spectroscopy of the Dwarf Nova CW Mon: The White Dwarf in Quiescence?

    Science.gov (United States)

    Hause, Connor; Sion, Edward M; Godon, Patrick; Boris, T Gänsicke; Szkody, Paula; de Martino, Domitilla; Pala, Anna

    2017-08-01

    We present a synthetic spectral analysis of the HST COS spectrum of the U Geminorum-type dwarf nova CW Mon, taken during quiescence as part of our COS survey of accreting white dwarfs in Cataclysmic Variables. We use synthetic photosphere and optically thick accretion disk spectra to model the COS spectrum as well as archival IUE spectra obtained decades ago when the system was in an even deeper quiescent state. Assuming a reddening of E(B-V)=0.06, an inclination of 60° (CW Mon has eclipses of the accretion disk, and a white dwarf mass of 0.8 M ⊙ , our results indicate the presence of a 22-27,000 K white dwarf and a low mass accretion rate [Formula: see text], for a derived distance o ~200 to ~300 pc.

  4. The Spatial Resolution of the COS FUV channel at Lifetime Position 4

    Science.gov (United States)

    Fox, Andrew

    2018-02-01

    In this ISR we report on the COS FUV spatial resolution at Lifetime Position 4 (LP4), as determined via analysis of the cross-dispersion spread functions (XDSFs). The XDSFs are predicted by the Code V optical model of the COS system and validated via high-S/N observations taken at LP4. We present analysis of the XDSFs in multiple central wavelength settings of the three COS FUV gratings: G130M, G160M, and G140L, deriving the dependence of the width (FWHM) of the XDSFs vs. wavelength. We find good agreement (RMS<1 pixel) between the predictions and the models on the FUVB segment, but in several settings the data are broader than the models by 1-2 pixels on FUVA.

  5. Cycle 24 COS NUV Dark Monitor Summary

    Science.gov (United States)

    Fix, Mees B.

    2018-02-01

    We summarize the Cycle 24 NUV Dark Monitoring Program for the Cosmic Origin Spectrograph (COS) on the Hubble Space Telescope (HST) covering dates November 2016 to October 2017. We give an overview of the calibration plan and summary for this calibration program.

  6. Soil atmosphere exchange of carbonyl sulfide (COS regulated by diffusivity depending on water-filled pore space

    Directory of Open Access Journals (Sweden)

    H. Van Diest

    2008-04-01

    Full Text Available The exchange of carbonyl sulfide (COS between soil and the atmosphere was investigated for three arable soils from Germany, China and Finland and one forest soil from Siberia for parameterization in the relation to ambient carbonyl sulfide (COS concentration, soil water content (WC and air temperature. All investigated soils acted as sinks for COS. A clear and distinct uptake optimum was found for the German, Chinese, Finnish and Siberian soils at 11.5%, 9%, 11.5%, and 9% soil WC, respectively, indicating that the soil WC acts as an important biological and physical parameter for characterizing the exchange of COS between soils and the atmosphere. Different optima of deposition velocities (Vd as observed for the Chinese, Finnish and Siberian boreal soil types in relation to their soil WC, aligned at 19% in relation to the water-filled pore space (WFPS, indicating the dominating role of gas diffusion. This interpretation was supported by the linear correlation between Vd and bulk density. We suggest that the uptake of COS depends on the diffusivity dominated by WFPS, a parameter depending on soil WC, soil structure and porosity of the soil.

  7. COS as a proxy for photosynthesis: foliage and soil contributions to ecosystem COS flux

    Science.gov (United States)

    Erkkilä, Kukka-Maaria; Kooijmans, Linda; Aalto, Juho; Chen, Huilin; Mammarella, Ivan; Maseyk, Kadmiel; Pihlatie, Mari; Seibt, Ulli; Sun, Wu; Vesala, Timo

    2017-04-01

    Traditionally the photosynthetic sink of CO2 (described by gross primary production, GPP) is defined from ecosystem scale measurements of CO2 flux taking into account respiration defined from the nighttime CO2 flux data. The problem with this method is the accurate determination of ecosystem respiration, since the respiratory processes can vary remarkably between daytime and nighttime. Carbonyl sulfide (COS) has been suggested to be a useful proxy for GPP since plants take up COS in a similar way as CO2 via their stomata. In contrast to CO2, there is no back-flux (respiration) of COS by plants and GPP can be calculated directly from COS flux measurements. However, leaf relative uptake (LRU) ratio, that is used when converting COS flux into GPP with a linear relation, has been treated as a constant and needs to be better determined for more accurate GPP estimates. This presentation shows the preliminary results of a measurement campaign organized in Hyytiälä Scots pine (Pinus sylvestris) stand in southern Finland during the growing season 2016. COS fluxes from the soil were measured with soil chambers over different vegetations. Pine and aspen branches were measured with branch chambers and ecosystem scale exchange was monitored via eddy covariance measurements. Preliminary results show night-time ecosystem uptake of COS (negative flux) that is about 15% of the daily uptake. Soil chambers show constantly negative COS fluxes, although there is no uptake of CO2 and the soil flux is about 25% of the total ecosystem flux. Pine and aspen branches seem to be sinks of COS throughout the day indicating open stomata during night-time. These findings suggest that negative ecosystem COS flux can be explained by soil and vegetation uptake during night-time. From branch chamber measurements we were able to calculate the leaf relative uptake (LRU) separately for aspen and pine. We find that LRU has an exponential correlation with photosynthetic active radiation (PAR) when PAR

  8. CONFERENCE NOTE: European Optical Society, Topical Meeting Optical Metrology and Nanotechnology, Engelberg, Switzerland, 27 30 March 1994

    Science.gov (United States)

    1993-01-01

    This meeting, organized by the Paul Scherrer Institute's Department of Applied Solid State Physics, will be held from 27 30 March 1994 at the Hotel Regina-Titlis, Engelberg, Switzerland. The aim is to bring together scientists from two important fields of current research and increasing industrial relevance. Optical metrology is a traditional discipline of applied optics which reached the nanometre scale a long time ago. Nanotechnology is setting new limits and represents a major challenge to metrology, as well as offering new opportunities to optics. The meeting is intended to help define a common future for optical metrology and nanotechnology. Topics to be covered include: nanometre position control and measuring techniques ultrahigh precision interferometry scanning probe microscopy (AFM, SNOM, etc.) surface modification by scanning probe methods precision surface fabrication and characterization nanolithography micro-optics, diffractive optics components, including systems and applications subwavelength optical structures synthetic optical materials structures and technologies for X-ray optics. For further information please contact: Jens Gobrecht (Secretary), Paul Scherrer Institute, CH-5232 Villigen-PSI, Switzerland.Tel. (41)56992529; Fax (41) 5698 2635.

  9. Seeking Balance between Individual and Society : Comparison of the Luxury Consumption Motivations between Chinese and Japanese Youth

    OpenAIRE

    Lu, Ying

    2012-01-01

    The purpose of this study is to explore the distinctions of luxury consumption motivations between Chinese and Japanese youth in the context of institutionalized individualization. It compares the different consumption motivations among Chinese and Japanese young people, as well as their respective inclinations between traditional and individualist consumption. It aims at identifying the underlying social factors that influence and contribute to the luxury consumptions in today’s China and Ja...

  10. Coping with the Challenges of Open Online Education in Chinese Societies in the Mobile Era: NTHU OCW as a Case Study

    Directory of Open Access Journals (Sweden)

    Shelley Shwu-Ching Young

    2014-07-01

    Full Text Available In an era witnessing the rapid development of information technology, mobile devices have brought revolutionary changes to learning. A single conventional media platform is not enough for the various mobile devices. Technology-enriched educational environments supported by different devices are important research issues nowadays. To capture the rapid growth of mobile users in Chinese societies, OpenCourseWare (OCW needs to move their learning models toward the mobile sphere. Therefore, this study reports the three years of empirical experience in implementing the upgraded National Tsing Hua University OCW platform and analyzes how users access the platform with various devices. The results indicate a responsive web design and cloud-computing provide great accessibility to meet the diversity of various mobile devices from Chinese users throughout the world, including 466,429 visits with 264 different mobile devices from 146 territories. Moreover, the proposed solutions make the workflow of OCW production more efficient. The study further discussed the importance of both tablets and smartphones. Moreover, to expand the reach of open educational resources (OER in Chinese societies, the critical issues of fair use and sustainability of OER should be of concern. The findings of the study provide valuable references for web engineers and educators to explore cross-device online learning using PCs and mobile devices.

  11. Estimating the contribution of bryophytes to the atmospheric COS budget

    Science.gov (United States)

    Gimeno, Teresa; Ogee, Jerome; Wingate, Lisa

    2017-04-01

    In the past decade, global biogeochemical modellers have embraced enthusiastically the potential of carbonyl sulphide (COS) as a tracer for gross primary productivity (GPP). COS is the most abundant sulphur-containing gas in the atmosphere, it is produced mainly in the ocean and it is consumed by the biosphere, with terrestrial vegetation being the most important contributor. Plant COS uptake is proportional to photosynthetic CO2 withdraw and that is why measurements of the biosphere-atmosphere COS flux can serve a proxy for GPP. Plant COS uptake is mediated by the light-independent enzyme carbonic anhydrase that irreversibly hydrolyses COS into H2S, which is quickly utilised as a sulphur source. Currently, there are no described plant-processes with COS as a by-product and hence the atmospheric-plant COS flux is assumed unidirectional. So far, we had focused on characterizing plant COS uptake dynamics on vascular plants and previous studies are consistent with the unidirectional flux assumption. However, although early works on sulphur metabolism suggested non-vascular plants might not abide to this assumption, we lack estimates of COS uptake dynamics for non-vascular communities. Bryophytes are key constituents of biocrusts and non-vascular photoautrophic communities and in temperate and cold latitudes contribute significantly to ecosystem carbon and nutrient cycling. We expect that in these ecosystems the coupling between COS and CO2 uptake will be influenced by specific environmental cues that control gas-exchange in bryophytes. We expect tissue hydration to be the most influential driver on COS uptake. In contrast, light would constrain CO2 but not COS uptake and therefore we expect greater uncoupling of COS and CO2 in the dark than in vascular plants. We characterized COS and CO2 uptake dynamics in two broadly distributed bryophytes, with contrasting life forms and evolutionary origins: the liverwort Marchantia polymorpha and the feather moss Scleropodium

  12. OA2 Chinese migrant peasant workers and the contradictory demands of filial piety in neo-liberal chinese society: a case study of filial end-of-life care in langzhong city.

    Science.gov (United States)

    He, Longtao

    2015-04-01

    Many scholars claim that recent changes to Chinese society since economic reform have challenged longstanding forms of informal social care, such as filial piety. For instance there is a societal tension at work in contemporary Chinese society today. On the one hand decreasing co-residence in multi-generational households caused by rural-urban migration, population ageing, the fall in fertility and 'One-Child Policy', and women's increasing participation in the labour market, emphasises an individualised, wage earning centred society. On the other hand, the Chinese government has sought to enforce a form of institutionalised filial piety through policies that legally require younger generations fulfil the full responsibility of care as there is no institutionalised equivalent of the welfare state to provide e.g. home help or personal care to the elderly whose relatives live and work at some distance. This places many younger generations in the contradiction of having to comply with neo-liberal labour market demands while also fulfilling state enforced filial piety. This research is to look at how Chinese migrant worker experience perceived filial responsibilities in relation to End-of-Life care for parents diagnosed with cancer in the current Chinese context. My PhD, based on interviews with migrant peasant workers caught in this dilemma by the demands of having a terminally ill parent, examines how Chinese migrant peasant workers negotiate and conduct their filial practices. The preliminary analysis of the interviews suggests that 'Filial Piety' is getting reconstructed in multifaceted ways as they negotiate the care dilemmas they face. The way they engage with the concept of filial piety enables and constrains how they can think about and practically organise their parents' care. The result would shed a light on evaluation of and suggestions for governmental policy-makings, such as the newly implemented Parent-Visiting law in China, in terms of better reinforcing

  13. Efficient propagation of progressive multifocal leukoencephalopathy-type JC virus in COS-7-derived cell lines stably expressing Tat protein of human immunodeficiency virus type 1.

    Science.gov (United States)

    Nukuzuma, Souichi; Nakamichi, Kazuo; Kameoka, Masanori; Sugiura, Shigeki; Nukuzuma, Chiyoko; Miyoshi, Isao; Takegami, Tsutomu

    2010-12-01

    The high incidence of progressive multifocal leukoencephalopathy (PML) in AIDS patients compared with many other immunosuppressive diseases suggests that HIV-1 infection is strictly related to the activation of JC virus (JCV) propagation. In this report, propagation of PML-type JCV in COS-7-derived cell lines stably expressing HIV-1 Tat (COS-tat cells) has been examined. In COS-tat cells, production of viral particles and replication of genomic DNA were markedly increased compared to COS-7 cells, as judged by HA and real-time PCR analyses. These results demonstrate that COS-tat cells provide a useful model system for studying HIV-1 Tat-mediated propagation of PML-type JCV. © 2010 The Societies and Blackwell Publishing Asia Pty Ltd.

  14. Broadband Optical Access Technologies to Converge towards a Broadband Society in Europe

    Science.gov (United States)

    Coudreuse, Jean-Pierre; Pautonnier, Sophie; Lavillonnière, Eric; Didierjean, Sylvain; Hilt, Benoît; Kida, Toshimichi; Oshima, Kazuyoshi

    This paper provides insights on the status of broadband optical access market and technologies in Europe and on the expected trends for the next generation optical access networks. The final target for most operators, cities or any other player is of course FTTH (Fibre To The Home) deployment although we can expect intermediate steps with copper or wireless technologies. Among the two candidate architectures for FTTH, PON (Passive Optical Network) is by far the most attractive and cost effective solution. We also demonstrate that Ethernet based optical access network is very adequate to all-IP networks without any incidence on the level of quality of service. Finally, we provide feedback from a FTTH pilot network in Colmar (France) based on Gigabit Ethernet PON technology. The interest of this pilot lies on the level of functionality required for broadband optical access networks but also on the development of new home network configurations.

  15. Decolonization, Educational Language Policy and Nation Building in Plural Societies: The Development of Chinese Education in Malaysia, 1950-1970

    Science.gov (United States)

    Sua, Tan Yao

    2013-01-01

    The two decades from 1950 to 1970 were a crucial period of educational reorganization in Malaysia that stemmed from the decolonization after the Second World War. This educational reorganization sought to address the perennial issue of nation building via educational language policy. The development of Chinese education was under severe threat as…

  16. Chinese descendants in East Asia under Japanese colonialism: the workshop on border societies ICAS 8, Macao, 25 June 2013

    NARCIS (Netherlands)

    Douw, L.

    2013-01-01

    Our workshop en gaged with the history of Chinese migrations around the countries of East Asia. There is a big challenge involved in this, especially when discussing the period of Japanese colonialism (1895-1945). For decades, the assertion of national interests has been preponderant in the public

  17. Living and dying with dignity in Chinese society: perspectives of older palliative care patients in Hong Kong.

    Science.gov (United States)

    Ho, Andy Hau Yan; Chan, Cecilia Lai Wan; Leung, Pamela Pui Yu; Chochinov, Harvey Max; Neimeyer, Robert A; Pang, Samantha Mei Che; Tse, Doris Man Wah

    2013-07-01

    the empirical Dignity Model has profoundly influenced the provision of palliative care for older terminally ill patients in the West, as it provides practical guidance and intervention strategies for promoting dignity and reducing distress at the end-of-life. to examine the concept of 'living and dying with dignity' in the Chinese context, and explore the generalisability of the Dignity Model to older terminal patients in Hong Kong. using qualitative interviews, the concept of dignity was explored among 16 older Chinese palliative care patients with terminal cancer. Framework analysis with both deductive and inductive methods was employed. the three major categories of themes of the Dignity Model were broadly supported. However, the subtheme of death anxiety was not supported, while two subthemes of generativity/legacy and resilience/fighting spirit manifested differently in the Chinese context. Furthermore, four new emergent themes have been identified. They include enduring pain, moral transcendence, spiritual surrender and transgenerational unity. these findings highlight both a cultural and a familial dimension in the construct of dignity, underline the paramount importance of cultural awareness and competence for working with ethnically diverse groups, and call for a culturally sensitive and family oriented approach to palliative care interventions with older Chinese terminal patients.

  18. Digital Holography and 3D Imaging: introduction to the joint feature issue in Applied Optics and Journal of the Optical Society of America A.

    Science.gov (United States)

    Kang, Hoonjong; Lee, Byoungho; Kozacki, Tomasz; Picart, Pascal; Situ, Guohai

    2018-01-01

    The OSA Topical Meeting on Digital Holography and 3D Imaging (DH) was held 29 May to 1 June 2017 on Jeju Island, South Korea. Feature issues based on the DH meeting series have been released by Applied Optics (AO) since 2007. This year, AO and the Journal of the Optical Society of America A (JOSA A) jointly decided to have one such feature issue in each journal. This feature issue includes 33 papers in AO and 9 in JOSA A and covers a large range of topics, reflecting the rapidly expanding techniques and applications of digital holography and 3D imaging. The upcoming DH meeting (DH 2018) will be held 25-28 June 2018 in Orlando, Florida, as part of the OSA Imaging and Applied Optics Congress.

  19. The Spectral Resolution of the COS FUV channel at Lifetime Position 4

    Science.gov (United States)

    Fox, Andrew; James, Bethan; Roman-Duval, Julia; Rafelski, Marc; Sonnentrucker, Paule

    2018-02-01

    In this ISR we report on the COS FUV spectral resolution at Lifetime Position 4 (LP4). We cover five central wavelength (cenwave) settings: G130M/1222, G130M/1291, G130M/1327, G160M/1577, and G160M/1623. We base our analysis on the profiles of narrow interstellar absorption lines in the COS FUV spectra of the SMC star AzV 75. We show that a high-resolution STIS E140M spectrum of AzV 75 convolved with the COS line spread functions (LSFs) generated by Code V optical models can successfully reproduce the observed COS line profiles at LP4. The spectral resolution at LP4 has degraded by 10-15% relative to LP3, as expected from the models. The highest resolution achievable is on the FUVA segment of the G160M cenwaves, where it reaches R=19,700 (FWHM=15.2 km/s) at 1780 Å. The resolution of the workhorse cenwave G130M/1291 varies from R=12 100 (24.8 km/s) at 1150 Å to R=16 900 (17.7 km/s) at 1450 Å.

  20. Cycle 24 COS FUV Detector Gain Maps

    Science.gov (United States)

    Sahnow, David

    2018-02-01

    Program 14519 used the onboard deuterium lamp to illuminate the LP3 region of the COS FUV detector immediately before and after the nominal high voltage on Segment B was changed on October 17, 2016. Exposures were also taken at LP2 approximately one year after the previous LP2 gain maps were obtained, and at LP3 using the G130M/1222 high voltage values. The pulse height information obtained was used to create gain maps in order to monitor the detector gain sag and to determine when high voltage changes and Lifetime Position changes were needed.

  1. Comparison of two optical biometers in Chinese school-aged children

    Directory of Open Access Journals (Sweden)

    Pei-Yang Shen

    2014-11-01

    Full Text Available AIM: To evaluate the repeatability of ocular biometrical measurements obtained from the optical low-coherence reflectometry(Lenstar LS900® version 1.10, as well as its agreement with the partial coherence interferometry(IOL Master® 500 version 7.1in Chinese school-aged children.METHODS: A prospective comparison of ocular biometrical measurements made by the Lenstar and IOL Master was performed on right eye of each participant. The intraobserver repeatability of Lenstar was assessed by coefficient of variation(CV. Agreement was analyzed using Bland-Altman plots.RESULTS: The mean age of the 110 subjects(range 6-15ywas 10.9±2.0y, and 54.5% were female. The Lenstar yielded repeatable measurements, with the smallest CV was obtained for axial length(AL(CVvs 23.88±1.27mm, Pvs 3.58±0.25mm, Pvs 7.56±0.27mm, PCONCLUSIONS: The Lenstar yielded excellent repeatability results of AL, ACD, and corneal curvature measurements, which were interchangeable with the IOL Master measurements in school-aged children.

  2. GROMOS polarizable charge-on-spring models for liquid urea: COS/U and COS/U2.

    Science.gov (United States)

    Lin, Zhixiong; Bachmann, Stephan J; van Gunsteren, Wilfred F

    2015-03-07

    Two one-site polarizable urea models, COS/U and COS/U2, based on the charge-on-spring model are proposed. The models are parametrized against thermodynamic properties of urea-water mixtures in combination with the polarizable COS/G2 and COS/D2 models for liquid water, respectively, and have the same functional form of the inter-atomic interaction function and are based on the same parameter calibration procedure and type of experimental data as used to develop the GROMOS biomolecular force field. Thermodynamic, dielectric, and dynamic properties of urea-water mixtures simulated using the polarizable models are closer to experimental data than using the non-polarizable models. The COS/U and COS/U2 models may be used in biomolecular simulations of protein denaturation.

  3. Measurement of optic tracts in normal Chinese adults of the Han nationality based on the high-resolution MRI

    International Nuclear Information System (INIS)

    Li Changying; Shi Linping; Zhang Yang; Wang Jian; Chen Nan; Wang Xing; Li Kuncheng; Zhuo Yan; Chen Lin

    2010-01-01

    Objective: To explore the morphological characteristics of optic tracts in healthy Chinese Han adults on the high-resolution MRI and fill the database of Chinese standard brain with morphological data of optic tracts. Methods: Cerebral MRI scans with T 1 WI 3D MPRAGE sequence of 1000 healthy Chinese volunteers from 15 hospitals were divided into five stages, ranging in age from 18 to 70. With the technique of multi-baseline, structure and morphology of optic tracts were displayed optimally on the images with multiplanar reconstruction. Data were measured as following: transverse distance of the cisternal optic tract (TD1) and peri-crural optic tract (TD2), length from the cisternal optic tract to the peri-crural optic tract (L), angle between optic tract(AOT) and height of optic tract from its first segment to plane of anterior commissure (H) including H1, H2, H3, H4 and H5. The measurements of optic tracts between sexualities and among age groups were compared by anasis of covariance; those among five age groups were compared pairwisedly by least significant difference analysis (LSD); and the differences of measurements between left and right optic tracts were analyzed using paired t test. Results: (1) Comparisons of optic tract structures between male and female: the mean optic tract length of male [(11.69±1.45),(11.56±1.44) mm] was significant longer than that of female [(10.58±1.29), (10.40±1.34) mm] (F=22.236, 29.703, P=0.000); the mean H1 of male [(2.56±0.28), (2.60±0.29) mm] and female [(2.57±0.31), (2.63±0.32) mm] were significantly different (F= 11.130,7.805, P=0.000, 0.005). No significant differences of the other measurements were found between male and female (P>0.05). (2) Comparisons among age groups: among 5 age groups, TD1 of both sides [left TD1 :(4.64 ± 0.51) ,(4.64 ± 0.57), (4.55 ± 0.58), (4.39 ± 0.53), (4.36 ± 0.58) mm; right TD1: (4.84 ± 0.53), (4.80 ± 0.60 ), (4.77 ± 0.65), (4.60 ± 0.59), (4.57 ± 0.59) mm ] and the right TD2

  4. Defining cosQ, the site required for termination of bacteriophage lambda DNA packaging.

    OpenAIRE

    Wieczorek, D J; Feiss, M

    2001-01-01

    Bacteriophage lambda is a double-stranded DNA virus that processes concatemeric DNA into virion chromosomes by cutting at specific recognition sites termed cos. A cos is composed of three subsites: cosN, the nicking site; cosB, required for packaging initiation; and cosQ, required for termination of chromosome packaging. During packaging termination, nicking of the bottom strand of cosN depends on cosQ, suggesting that cosQ is needed to deliver terminase to the bottom strand of cosN to carry ...

  5. EDITORIAL: Special section: Selected papers from OMS'05, the 1st Topical Meeting of the European Optical Society on Optical Microsystems (OMS)

    Science.gov (United States)

    Rendina, Ivo; Fazio, Eugenio; Ferraro, Pietro

    2006-07-01

    OMS'05 is the first international conference wholly dedicated to optical microsystems. It was organized by the European Optical Society (EOS) in the frame of its international topical meeting activity and was held in Italy, September 2005, amidst the wonderful scenery of the Island of Capri. A possible definition of an optical microsystem is a complex system, able to perform one or more sensing and actuation functions, where optical devices are integrated in a smart way with electronic, mechanical and sensing components by taking advantage of the progress in micro- and nano-technologies. The increasing interest in this field arises from the expected applications that would significantly improve the quality of life. The list of possibilities offered by the optical microsystem enabling technologies is very long and seems to increase day by day. We are not only thinking about the next generation of optical telecommunication networks and computers, but also about low-cost, compact microsystems for environmental monitoring, in order to improve safety in the avionic and automotive fields, medical diagnostics and proteomic/genomic studies, or just finding general applications in several industrial fields. The goal of the conference was to involve scientists and young researchers from the main public and private laboratories, giving them the opportunity to present new scientific results and compare their know-how in the exciting and emerging field of optical microsystems. We believe that we succeeded in this. More than 200 scientists from all over the world attended the conference. We had more than 100 oral presentations and approximately 20 from the keynote lectures and invited speeches. It was an opportunity to define the most recent progress carried out in the field and to outline the possible road-map leading to the expected results in the industrial and social fields. We strongly believe that research and technology are closely interconnected at present and cannot

  6. Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families

    International Nuclear Information System (INIS)

    Zhou Xiangtian; Wei Qiping; Yang Li; Tong Yi; Zhao Fuxin; Lu Chunjie; Qian Yaping; Sun Yanghong; Lu Fan; Qu Jia; Guan Minxin

    2006-01-01

    We report here the clinical, genetic, and molecular characterization of five Chinese families with Leber's hereditary optic neuropathy (LHON). Clinical and genetic evaluations revealed the variable severity and age-of-onset in visual impairment in these families. Strikingly, there were extremely low penetrances of visual impairment in these Chinese families. Sequence analysis of the complete mitochondrial genomes in these pedigrees showed the distinct sets of mtDNA polymorphism, in addition to the identical ND4 G11696A mutation associated with LHON. Indeed, this mutation is present in homoplasmy only in the maternal lineage of those pedigrees but not other members of these families. In fact, the occurrence of the G11696A mutation in these several genetically unrelated subjects affected by visual impairment strongly indicates that this mutation is involved in the pathogenesis of visual impairment. Furthermore, the N405D in the ND5 and G5820A in the tRNA Cys , showing high evolutional conservation, may contribute to the phenotypic expression of G11696A mutation in the WZ10 pedigree. However, there was the absence of functionally significant mtDNA mutations in other four Chinese pedigrees carrying the G11696A mutation. Therefore, nuclear modifier gene(s) or environmental factor(s) may play a role in the phenotypic expression of the LHON-associated G11696A mutation in these Chinese pedigrees

  7. Aerosol optical depth (AOD) and Angstrom exponent of aerosols observed by the Chinese Sun Hazemeter Network from August 2004 to September 2005

    Science.gov (United States)

    Jinyuan Xin; Yuesi Wang; Zhanqing Li; Pucai Wang; Wei Min Hao; Bryce L. Nordgren; Shigong Wang; Guangren Lui; Lili Wang; Tianxue Wen; Yang Sun; Bo Hu

    2007-01-01

    To reduce uncertainties in the quantitative assessment of aerosol effects on regional climate and environmental changes, extensive measurements of aerosol optical properties were made with handheld Sun photometers in the Chinese Sun Hazemeter Network (CSHNET) starting in August 2004. Regional characteristics of the aerosol optical depth (AOD) at 500 nm and Angstrom...

  8. Science and Society: The Case of Acceptance of Newtonian Optics in the Eighteenth Century

    Science.gov (United States)

    Silva, Cibelle Celestino; Moura, Breno Arsioli

    2012-01-01

    The present paper presents a historical study on the acceptance of Newton's corpuscular theory of light in the early eighteenth century. Isaac Newton first published his famous book "Opticks" in 1704. After its publication, it became quite popular and was an almost mandatory presence in cultural life of Enlightenment societies. However, Newton's…

  9. 33 CFR 110.58 - Cos Cob Harbor, Greenwich, Conn.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cos Cob Harbor, Greenwich, Conn. 110.58 Section 110.58 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.58 Cos Cob Harbor, Greenwich, Conn. (a) Area A...

  10. Expression of functional human C1 inhibitor in COS cells

    NARCIS (Netherlands)

    Eldering, E.; Nuijens, J. H.; Hack, C. E.

    1988-01-01

    Full length human C1 inhibitor cDNA was cloned into a vector suitable for transient expression in COS-1 cells. Transfected COS cells secreted an immunoreactive protein of Mr approximately 110,000 that appeared to be functionally equivalent to the plasma-derived protein as established by the

  11. Association of parental warmth and harsh discipline with developmental trajectories of depressive symptoms among adolescents in Chinese society.

    Science.gov (United States)

    Wang, Yu-Chung Lawrence; Chan, Hsun-Yu; Lin, Ching-Wen; Li, Jia-Ru

    2015-12-01

    This article examines the relationship between parenting styles and the development of depressive symptoms among adolescents. We analyzed a nationally representative longitudinal data set of adolescents aged 12 to 14 in Taiwan. Results from growth mixture modeling revealed a nonlinear increase in the intensity of depressive symptoms between early and middle adolescence. More pronounced depressive symptoms in earlier years were also shown to be associated with more rapid development of similar symptoms later in adolescence. Perceived parenting styles, as manifest in parental warmth and harsh discipline, were categorized into 4 latent heterogeneous classes: attentive, reserved, austere, and conflicting. Adolescents living under austere parenting tend to report the most pronounced depressive symptoms from early to middle adolescence; however, the development of symptoms in this group was the slowest. We also discuss the role of harsh parenting in Chinese culture, as it pertains to the roles traditionally assumed by the father and mother. (c) 2015 APA, all rights reserved).

  12. Proceedings of the establishment conference of Professional Committee on Waste Underground Disposal of Chinese Society for Rock Mechanics and Engineering and the first academic seminar

    International Nuclear Information System (INIS)

    2006-07-01

    Approved by the China Association for Science and Technology, Chinese Society for Rock Mechanics and Engineering newly established 'Professional Committee on Waste Underground Disposal'. The committee will organise the national and international academic exchange, and provide advice on discipline development, sustainable industrial development, environmental protection, etc.. This is the establishing conference of the professional committee, as well as the first academic seminar. The following topics on waste underground disposal are discussed: the theory, practice and exploration, project examples, new technologies and new methods. The contents include: waste disposal technology in the new century, the geological disposal of high level radioactive waste, LLW and ILW underground waste disposal, urban and industrial waste underground disposal, and etc.

  13. Development and Pilot Evaluation of a Novel Dignity-Conserving End-of-Life (EoL) Care Model for Nursing Homes in Chinese Societies.

    Science.gov (United States)

    Ho, Andy H Y; Dai, Annie A N; Lam, Shu-Hang; Wong, Sandy W P; Tsui, Amy L M; Tang, Jervis C S; Lou, Vivian W Q

    2016-06-01

    The provision of end-of-life (EoL) care in long-term-care settings remains largely underdeveloped in most Chinese societies, and nursing home residents often fail to obtain good care as they approach death. This paper systematically describes the development and implementation mechanisms of a novel Dignity-Conserving EoL Care model that has been successfully adopted by three nursing homes in Hong Kong and presents preliminary evidence of its effectiveness on enhancing dignity and quality of life (QoL) of terminally ill residents. Nine terminally ill nursing home residents completed the McGill Quality of Life Questionnaire and the Nursing Facilities Quality of Life Questionnaire at baseline and 6 months post-EoL program enrollment. Wilcoxon signed rank test was used to detect significance changes in each QoL domains across time. Although significant deterioration was recorded for physical QoL, significant improvement was observed for social QoL. Moreover, a clear trend toward significant improvements was identified for the QoL domains of individuality and relationships. A holistic and compassionate caring environment, together with the core principles of family-centered care, interagency and interdisciplinary teamwork, as well as cultural-specific psycho-socio-spiritual support, are all essential elements for optimizing QoL and promoting death with dignity for nursing home residents facing morality. This study provides a useful framework to facilitate the future development of EoL care in long-term-care settings in the Chinese context. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. [History and development of Chinese orthodontics].

    Science.gov (United States)

    Lin, Jiu-Xiang; Xu, Tian-Min

    2008-02-18

    Orthodontics in China has experienced two important stages. At its early stage from 1950's to 1970's orthodontics was a division of prosthodontic department in China. There were 3 top professors in this field, who got partly training at one time or another in USA and returned to China working in Beijing Medical College, the Fourth Military Medical University and Shanghai Second Medical College. Among them, Professor Mao of Beijing Medical College was regarded as the father of Chinese Orthodontics. Removable appliance was the main tool at that stage and Prof.Mao brought forward Mao's Classification of Malocclusion which is still used in China. The rapid developing stage began in the 1980's when China opened its door to the world. More and more orthodontists got further training abroad and brought back advanced techniques since then. Up to now, we have already had more than one thousand of orthodontic specialists and established its own organization--the Chinese Orthodontic Society (COS), which holds domestic orthodontic meetings and organize its members to attend international meetings. Right now, almost all advanced techniques in diagnosis and treatment are adopted in China, including 3D imaging, self-ligating bracket appliance, and implant anchorage. Chinese orthodontists have started to present or publish papers in international meetings and journals and more than that, started to develop new appliances, such as Driving-Force Straight Wire Appliance, which has shown advantages in treating skeletal Class III malocclusion.

  15. Moving COS FUV Spectra to the Third COS FUV Lifetime Position

    Science.gov (United States)

    Proffitt, Charles R.; Bostroem, K. Azalee; Debes, John H.; Ely, Justin; Hernandez, Svea; Hodge, Philip; Jedrzejewski, Robert I.; Lindsay, Kevin; Massa, Derck; Oliveira, Cristina M.; Penton, Steven V.; Roman-Duval, Julia; Sahnow, David J.; Sana, Hugues; Sonnentrucker, Paul; Taylor, Joanna M.

    2014-06-01

    In the fall of 2014, the location of COS FUV spectra on the detector is expected to be moved from the second COS FUV Lifetime Position (LP2) to the third COS FUV Lifetime Position (LP3). This move is needed to mitigate the continuing effects of gain sag in the microchannel plate detectors. With the LP2 move (July 2012) spectra were shifted perpendicularly to the dispersion direction by the equivalent of +3.5", or about 41 pixels, from the original LP1 location. With the LP3 move, spectra will be shifted below the original LP1 position by about -2.5", which maximizes resolution and the detector area available for future lifetime positions. The modes with the widest profiles perpendicular to the dispersion, G130M 1055 and 1096, will remain at LP2, while all other modes will be moved to LP3. Improved extraction techniques are being developed to ensure that the gain sagged regions near LP1 do not affect the spectral quality of point source observations at LP3. We will present results from preliminary tests near LP3 and discuss the implications for science observations. Typical spectral resolving power (λ/Δλ) for the modes that are moved to LP3 may decline by about 15% relative to the performance at LP2. Observations of spatially extended sources may also be slightly impacted by the proximity to the gain sagged regions near the original LP1 location and care may be needed not to confuse gain sag artifacts with real spectral features for such sources. Instrument performance is otherwise expected to be similar to that seen during Cycle 21.

  16. Electrical, optical, and magnetic properties of organic solid-state materials IV. Materials Research Society, symposium proceedings Volume 488

    International Nuclear Information System (INIS)

    Reynolds, J.R.; Jen, A.K.Y.; Rubner, M.F.; Chiang, L.Y.; Dalton, L.R.

    1998-01-01

    The symposium, Electrical, Optical, and Magnetic Properties of Organic Solid-State Materials IV, was sponsored by the Materials Research Society and held December 1--5, 1997, in Boston, Massachusetts. Early studies of charge transport in conducting polymers have evolved from the elucidation of fundamental structure/function relationships to applications as batteries, simple electrical devices such as diodes, chemical sensors, antistatic coatings, microwave and millimeter wave-absorbing materials, and photochromic devices. A particularly exciting evolution has been the discovery and development of organic light-emitting diodes (OLEDs) which appear to be nearing commercialization in an amazingly short period of time. This application is of particular interest because both electrical and optical properties must be considered, and these have been important parallel themes of the conference. Moreover, nanostructure control is important for OLEDs, and nanoscale architectural engineering has been an increasingly important theme of the conference. Indeed, not only has the study of conjugated (quasidelocalized) electrons in organic solid-state materials resulted in interesting physical properties and device applications, but the desire to exploit these properties has promoted the development of new synthesis and processing methodologies to achieve special nanoscale and microscale structures. One hundred five papers have been processed separately for inclusion on the data base

  17. The final COS-B database now publicly available

    Science.gov (United States)

    Mayer-Hasselwander, H. A.; Bennett, K.; Bignami, G. F.; Bloemen, J. B. G. M.; Buccheri, R.; Caraveo, P. A.; Hermsen, W.; Kanbach, G.; Lebrun, F.; Paul, J. A.

    1985-01-01

    The data obtained by the gamma ray satellite COS-B was processed, condensed and integrated together with the relevant mission and experiment parameters into the Final COS-B Database. The database contents and the access programs available with the database are outlined. The final sky coverage and a presentation of the large scale distribution of the observed Milky Way emission are given. The database is announced to be available through the European Space Agency.

  18. COS in the stratosphere. [sulfuric acid aerosol precursor

    Science.gov (United States)

    Inn, E. C. Y.; Vedder, J. F.; Tyson, B. J.; Ohara, D.

    1979-01-01

    Carbonyl sulfide (COS) has been detected in the stratosphere, and mixing ratio measurements are reported for altitudes of 15.2 to 31.2 km. A large volume, cryogenic sampling system mounted on board a U-2 aircraft has been used for lower stratosphere measurements and a balloon platform for measurement at 31.2 km. These observations and measurements strongly support the concept that stratospheric COS is an important precursor in the formation of sulfuric acid aerosols.

  19. Assessing canopy performance using carbonyl sulfide (COS) measurements.

    Science.gov (United States)

    Yang, Fulin; Qubaja, Rafat; Tatarinov, Fyodor; Rotenberg, Eyal; Yakir, Dan

    2018-03-25

    Carbonyl sulfide (COS) is a tracer of ecosystem photosynthesis that can advance carbon cycle research from leaf to global scales; however, a range of newly reported caveats related to sink/source strength of various ecosystem components hinder its application. Using comprehensive eddy-covariance and chamber measurements, we systematically measure ecosystem contributions from leaf, stem, soil and litter and were able to close the ecosystem COS budget. The relative contributions of non-photosynthetic components to the overall canopy-scale flux are relatively small (~4% during peak activity season) and can be independently estimated based on their responses to temperature and humidity. Converting COS to photosynthetic CO 2 fluxes based on the leaf relative uptake of COS/CO 2 , faces challenges due to observed daily and seasonal changes. Yet, this ratio converges around a constant value (~1.6), and the variations, dominated by light intensity, were found unimportant on a flux-weighted daily time-scale, indicating a mean ratio of daytime gross-to-net primary productivity of ~2 in our ecosystem. The seasonal changes in the leaf relative uptake ratio may indicate a reduction in mesophyll conductance in winter, and COS-derived canopy conductance permitted canopy temperature estimate consistent with radiative skin temperature. These results support the feasibility of using COS as a powerful and much-needed means of assessing ecosystem function and its response to change. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  20. Bryophyte gas-exchange dynamics along varying hydration status reveal a significant carbonyl sulphide (COS) sink in the dark and COS source in the light.

    Science.gov (United States)

    Gimeno, Teresa E; Ogée, Jérôme; Royles, Jessica; Gibon, Yves; West, Jason B; Burlett, Régis; Jones, Sam P; Sauze, Joana; Wohl, Steven; Benard, Camille; Genty, Bernard; Wingate, Lisa

    2017-08-01

    Carbonyl sulphide (COS) is a potential tracer of gross primary productivity (GPP), assuming a unidirectional COS flux into the vegetation that scales with GPP. However, carbonic anhydrase (CA), the enzyme that hydrolyses COS, is expected to be light independent, and thus plants without stomata should continue to take up COS in the dark. We measured net CO 2 (A C ) and COS (A S ) uptake rates from two astomatous bryophytes at different relative water contents (RWCs), COS concentrations, temperatures and light intensities. We found large A S in the dark, indicating that CA activity continues without photosynthesis. More surprisingly, we found a nonzero COS compensation point in light and dark conditions, indicating a temperature-driven COS source with a Q 10 (fractional change for a 10°C temperature increase) of 3.7. This resulted in greater A S in the dark than in the light at similar RWC. The processes underlying such COS emissions remain unknown. Our results suggest that ecosystems dominated by bryophytes might be strong atmospheric sinks of COS at night and weaker sinks or even sources of COS during daytime. Biotic COS production in bryophytes could result from symbiotic fungal and bacterial partners that could also be found on vascular plants. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  1. Soil-atmosphere carbonyl sulfide (COS) exchange in a tropical rainforest at La Selva, Costa Rica

    Science.gov (United States)

    Sun, W.; Maseyk, K. S.; Juarez, S.; Lett, C.; Seibt, U. H.

    2014-12-01

    Carbonyl sulfide (COS) has recently been proposed as a promising tracer for partitioning ecosystem carbon assimilation due to the close analogy between leaf uptake processes of COS and CO2. This emerging framework requires accurate characterization of the source and sink components of COS, including soil fluxes. Here we present the first direct, continuous observations of soil COS fluxes for 4 months at a tropical rainforest, La Selva Biological Station, Costa Rica. Three soil plots with contrasting water content were selected for chamber measurements. Our observations confirmed that soils are principally COS sinks, with daily mean COS fluxes averaged across all chambers ranging from -3 to 0 pmol m-2 s-1. When compared with net ecosystem COS uptake which peaks around -30 pmol m-2 s-1, their contributions should be considered in ecosystem COS balance. We did not find a temperature optimum, but soil COS uptake slightly increased with soil temperature, indicating biotic control on soil COS fluxes. Diurnal cycles of COS fluxes were observed during drying out periods after rain. The diel periodicity of COS fluxes was probably obscured by frequent raining at the site. Diffusional control of soil COS fluxes is shown from increasing soil COS uptake at lower soil water-filled pore space. These confirm that soil COS fluxes are mediated both by soil physical and biological factors. Using a depth-resolved diffusion-reaction model with data-driven enzyme activity parameterization, we simulated the COS fluxes from measured soil environmental variables, consistent with observations. This modeling scheme is useful for separating soil COS fluxes from net ecosystem COS fluxes, which lends support to the emergent COS-based approach of carbon flux partitioning.

  2. Only male matrilineal relatives with Leber's hereditary optic neuropathy in a large Chinese family carrying the mitochondrial DNA G11778A mutation

    International Nuclear Information System (INIS)

    Qu Jia; Li Ronghua; Tong Yi; Hu Yongwu; Zhou Xiangtian; Qian Yaping; Lu Fan; Guan Minxin

    2005-01-01

    We report here the characterization of a five-generation large Chinese family with Leber's hereditary optic neuropathy (LHON). Very strikingly, six affected individuals of 38 matrilineal relatives (17 females/21 males) are exclusively males in this Chinese family. These matrilineal relatives in this family exhibited late-onset/progressive visual impairment with a wide range of severity, ranging from blindness to normal vision. The age of onset in visual impairment varies from 17 to 30 years. Sequence analysis of the complete mitochondrial genome in this pedigree revealed the presence of the G11778A mutation in ND4 gene and 29 other variants. This mitochondrial genome belongs to the Southern Chinese haplogroup B5b. We showed that the G11778A mutation is present at near homoplasmy in matrilineal relatives of this Chinese family but not in 164 Chinese controls. Incomplete penetrance of LHON in this family indicates the involvement of modulatory factors in the phenotypic expression of visual dysfunction associated with the G11778A mutation. However, none of other mtDNA variants are evolutionarily conserved and implicated to have significantly functional consequence. Thus, nuclear modifier gene(s) or environmental factor(s) seem to account for the penetrance and phenotypic variability of LHON in this Chinese family carrying the G11778A mutation

  3. Core Outcome Set–STAndards for Reporting: The COS-STAR Statement

    Science.gov (United States)

    Kirkham, Jamie J.; Gorst, Sarah; Altman, Douglas G.; Blazeby, Jane M.; Clarke, Mike; Devane, Declan; Moher, David; Schmitt, Jochen; Tugwell, Peter; Tunis, Sean; Williamson, Paula R.

    2016-01-01

    Background Core outcome sets (COS) can enhance the relevance of research by ensuring that outcomes of importance to health service users and other people making choices about health care in a particular topic area are measured routinely. Over 200 COS to date have been developed, but the clarity of these reports is suboptimal. COS studies will not achieve their goal if reports of COS are not complete and transparent. Methods and Findings In recognition of these issues, an international group that included experienced COS developers, methodologists, journal editors, potential users of COS (clinical trialists, systematic reviewers, and clinical guideline developers), and patient representatives developed the Core Outcome Set–STAndards for Reporting (COS-STAR) Statement as a reporting guideline for COS studies. The developmental process consisted of an initial reporting item generation stage and a two-round Delphi survey involving nearly 200 participants representing key stakeholder groups, followed by a consensus meeting. The COS-STAR Statement consists of a checklist of 18 items considered essential for transparent and complete reporting in all COS studies. The checklist items focus on the introduction, methods, results, and discussion section of a manuscript describing the development of a particular COS. A limitation of the COS-STAR Statement is that it was developed without representative views of low- and middle-income countries. COS have equal relevance to studies conducted in these areas, and, subsequently, this guideline may need to evolve over time to encompass any additional challenges from developing COS in these areas. Conclusions With many ongoing COS studies underway, the COS-STAR Statement should be a helpful resource to improve the reporting of COS studies for the benefit of all COS users. PMID:27755541

  4. Core Outcome Set-STAndards for Reporting: The COS-STAR Statement.

    Science.gov (United States)

    Kirkham, Jamie J; Gorst, Sarah; Altman, Douglas G; Blazeby, Jane M; Clarke, Mike; Devane, Declan; Gargon, Elizabeth; Moher, David; Schmitt, Jochen; Tugwell, Peter; Tunis, Sean; Williamson, Paula R

    2016-10-01

    Core outcome sets (COS) can enhance the relevance of research by ensuring that outcomes of importance to health service users and other people making choices about health care in a particular topic area are measured routinely. Over 200 COS to date have been developed, but the clarity of these reports is suboptimal. COS studies will not achieve their goal if reports of COS are not complete and transparent. In recognition of these issues, an international group that included experienced COS developers, methodologists, journal editors, potential users of COS (clinical trialists, systematic reviewers, and clinical guideline developers), and patient representatives developed the Core Outcome Set-STAndards for Reporting (COS-STAR) Statement as a reporting guideline for COS studies. The developmental process consisted of an initial reporting item generation stage and a two-round Delphi survey involving nearly 200 participants representing key stakeholder groups, followed by a consensus meeting. The COS-STAR Statement consists of a checklist of 18 items considered essential for transparent and complete reporting in all COS studies. The checklist items focus on the introduction, methods, results, and discussion section of a manuscript describing the development of a particular COS. A limitation of the COS-STAR Statement is that it was developed without representative views of low- and middle-income countries. COS have equal relevance to studies conducted in these areas, and, subsequently, this guideline may need to evolve over time to encompass any additional challenges from developing COS in these areas. With many ongoing COS studies underway, the COS-STAR Statement should be a helpful resource to improve the reporting of COS studies for the benefit of all COS users.

  5. A note on the assignments of Rydberg states of COS

    Science.gov (United States)

    Wu, C. Y. R.

    1982-01-01

    Assignments of the Rydberg states which converge to the respective X-tilde and B-tilde ion states of the COS(+) ion are reported. The assignments were made based on previously established orderings for the quantum defects of isoelectronic molecules. The Rydberg series I and II, which converge to the X-tilde 2 Pi state of COS(+), and the series III, IV, V, VI and VII, which converge to the B-tilde 2 Sigma + state, are assigned to molecular orbitals characterized by predominant sulfur orbitals, in contrast to those converging to the C-tilde states, which are characterized by oxygen atomic orbitals.

  6. Semi-automated International Cartilage Repair Society scoring of equine articular cartilage lesions in optical coherence tomography images.

    Science.gov (United States)

    Te Moller, N C R; Pitkänen, M; Sarin, J K; Väänänen, S; Liukkonen, J; Afara, I O; Puhakka, P H; Brommer, H; Niemelä, T; Tulamo, R-M; Argüelles Capilla, D; Töyräs, J

    2017-07-01

    Arthroscopic optical coherence tomography (OCT) is a promising tool for the detailed evaluation of articular cartilage injuries. However, OCT-based articular cartilage scoring still relies on the operator's visual estimation. To test the hypothesis that semi-automated International Cartilage Repair Society (ICRS) scoring of chondral lesions seen in OCT images could enhance intra- and interobserver agreement of scoring and its accuracy. Validation study using equine cadaver tissue. Osteochondral samples (n = 99) were prepared from 18 equine metacarpophalangeal joints and imaged using OCT. Custom-made software was developed for semi-automated ICRS scoring of cartilage lesions on OCT images. Scoring was performed visually and semi-automatically by five observers, and levels of inter- and intraobserver agreement were calculated. Subsequently, OCT-based scores were compared with ICRS scores based on light microscopy images of the histological sections of matching locations (n = 82). When semi-automated scoring of the OCT images was performed by multiple observers, mean levels of intraobserver and interobserver agreement were higher than those achieved with visual OCT scoring (83% vs. 77% and 74% vs. 33%, respectively). Histology-based scores from matching regions of interest agreed better with visual OCT-based scoring than with semi-automated OCT scoring; however, the accuracy of the software was improved by optimising the threshold combinations used to determine the ICRS score. Images were obtained from cadavers. Semi-automated scoring software improved the reproducibility of ICRS scoring of chondral lesions in OCT images and made scoring less observer-dependent. The image analysis and segmentation techniques adopted in this study warrant further optimisation to achieve better accuracy with semi-automated ICRS scoring. In addition, studies on in vivo applications are required. © 2016 EVJ Ltd.

  7. The Society for Translational Medicine

    DEFF Research Database (Denmark)

    Gao, Shugeng; Zhang, Zhongheng; Aragón, Javier

    2017-01-01

    The Society for Translational Medicine and The Chinese Society for Thoracic and Cardiovascular Surgery conducted a systematic review of the literature in an attempt to improve our understanding in the postoperative management of chest tubes of patients undergoing pulmonary lobectomy. Recommendati......The Society for Translational Medicine and The Chinese Society for Thoracic and Cardiovascular Surgery conducted a systematic review of the literature in an attempt to improve our understanding in the postoperative management of chest tubes of patients undergoing pulmonary lobectomy...

  8. Regulation of oxidative stress response by CosR, an essential response regulator in Campylobacter jejuni.

    Directory of Open Access Journals (Sweden)

    Sunyoung Hwang

    Full Text Available CosR (Campylobacter oxidative stress regulator; Cj0355c is an OmpR-type response regulator essential for the viability of Campylobacter jejuni, a leading foodborne pathogen causing human gastroenteritis worldwide. Despite importance, the function of CosR remains completely unknown mainly because of cell death caused by its knockout mutation. To overcome this technical limitation, in this study, antisense technology was used to investigate the regulatory function of CosR by modulating the level of CosR expression. Two-dimensional gel electrophoresis (2DGE was performed to identify the CosR regulon either by suppressing CosR expression with antisense peptide nucleic acid (PNA or by overexpressing CosR in C. jejuni. According to the results of 2DGE, CosR regulated 32 proteins involved in various cellular processes. Notably, CosR negatively regulated a few key proteins of the oxidative stress response of C. jejuni, such as SodB, Dps, Rrc and LuxS, whereas CosR positively controlled AhpC. Electrophoretic mobility shift assay showed that CosR directly bound to the promoter region of the oxidative stress genes. DNase I footprinting assays identified 21-bp CosR binding sequences in the sodB and ahpC promoters, suggesting CosR specifically recognizes and binds to the regulated genes. Interestingly, the level of CosR protein was significantly reduced by paraquat (a superoxide generator but not by hydrogen peroxide. Consistent with the overall negative regulation of oxidative stress defense proteins by CosR, the CosR knockdown by antisense rendered C. jejuni more resistant to oxidative stress compared to the wild type. Overall, this study reveals the important role played by the essential response regulator CosR in the oxidative stress defense of C. jejuni.

  9. A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family

    Science.gov (United States)

    Zhang, Liping; Shi, Wei; Song, Liming; Zhang, Xiao; Cheng, Lulu; Wang, Yanfang; Ge, Xianglian; Li, Wei; Zhang, Wei; Min, Qingjie; Jin, Zi-Bing; Qu, Jia; Gu, Feng

    2014-11-01

    Autosomal dominant optic atrophy (ADOA) is the most frequent form of hereditary optic neuropathy and occurs due to the degeneration of the retinal ganglion cells. To identify the genetic defect in a family with putative ADOA, we performed capture next generation sequencing (CNGS) to screen known retinal disease genes. However, six exons failed to be sequenced by CNGS in optic atrophy 1 gene (OPA1). Sequencing of those exons identified a 4 bp deletion mutation (c.2983-1_2985del) in OPA1. Furthermore, we sequenced the transcripts of OPA1 from the patient skin fibroblasts and found there is six-nucleotide deletion (c.2984-c.2989, AGAAAG). Quantitative-PCR and Western blotting showed that OPA1 mRNA and its protein expression have no obvious difference between patient skin fibroblast and control. The analysis of protein structure by molecular modeling suggests that the mutation may change the structure of OPA1 by formation of an alpha helix protruding into an existing pocket. Taken together, we identified an OPA1 mutation in a family with ADOA by filling the missing CNGS data. We also showed that this mutation affects the structural intactness of OPA1. It provides molecular insights for clinical genetic diagnosis and treatment of optic atrophy.

  10. Così fan tutte: Brilliance or Buffoonery?

    Directory of Open Access Journals (Sweden)

    Sarah Whitfield

    2011-12-01

    Full Text Available Hardly any opera has endured more scrutiny and self-preserving apology than Mozart’s Così fan tutte. Flagrant opposition and a long string of “rescue” attempts shroud the receptive history of the work. Since its premiere, Così fan tutte has long been recognized as a problem opera. Many critics found it implausible that Mozart—the consummate composer and man that warranted their idolization—could have stooped so low as to agree to such an immoral plot. The great beauty in Mozart’s musical parody is that it at once mocks and transforms the supposed superficial experiment of Lorenzo Da Ponte’s libretto. The parody in Così fan tutte must be correctly interpreted. It is rampant, but it exists for much more than a perfunctory laugh. The beauty of Mozart’s music—in both moments of wild parody and heartfelt emotion—succeeds in giving Così fan tutte a depth that is both challenging and transforming.

  11. Option pricing with COS method on Graphics Processing Units

    NARCIS (Netherlands)

    B. Zhang (Bo); C.W. Oosterlee (Cornelis)

    2009-01-01

    htmlabstractIn this paper, acceleration on the GPU for option pricing by the COS method is demonstrated. In particular, both European and Bermudan options will be discussed in detail. For Bermudan options, we consider both the Black-Scholes model and Levy processes of infinite activity. Moreover,

  12. Core Outcome Set-STAndards for Development: The COS-STAD recommendations.

    Science.gov (United States)

    Kirkham, Jamie J; Davis, Katherine; Altman, Douglas G; Blazeby, Jane M; Clarke, Mike; Tunis, Sean; Williamson, Paula R

    2017-11-01

    The use of core outcome sets (COS) ensures that researchers measure and report those outcomes that are most likely to be relevant to users of their research. Several hundred COS projects have been systematically identified to date, but there has been no formal quality assessment of these studies. The Core Outcome Set-STAndards for Development (COS-STAD) project aimed to identify minimum standards for the design of a COS study agreed upon by an international group, while other specific guidance exists for the final reporting of COS development studies (Core Outcome Set-STAndards for Reporting [COS-STAR]). An international group of experienced COS developers, methodologists, journal editors, potential users of COS (clinical trialists, systematic reviewers, and clinical guideline developers), and patient representatives produced the COS-STAD recommendations to help improve the quality of COS development and support the assessment of whether a COS had been developed using a reasonable approach. An open survey of experts generated an initial list of items, which was refined by a 2-round Delphi survey involving nearly 250 participants representing key stakeholder groups. Participants assigned importance ratings for each item using a 1-9 scale. Consensus that an item should be included in the set of minimum standards was defined as at least 70% of the voting participants from each stakeholder group providing a score between 7 and 9. The Delphi survey was followed by a consensus discussion with the study management group representing multiple stakeholder groups. COS-STAD contains 11 minimum standards that are the minimum design recommendations for all COS development projects. The recommendations focus on 3 key domains: the scope, the stakeholders, and the consensus process. The COS-STAD project has established 11 minimum standards to be followed by COS developers when planning their projects and by users when deciding whether a COS has been developed using reasonable

  13. Core Outcome Set-STAndards for Development: The COS-STAD recommendations.

    Directory of Open Access Journals (Sweden)

    Jamie J Kirkham

    2017-11-01

    Full Text Available The use of core outcome sets (COS ensures that researchers measure and report those outcomes that are most likely to be relevant to users of their research. Several hundred COS projects have been systematically identified to date, but there has been no formal quality assessment of these studies. The Core Outcome Set-STAndards for Development (COS-STAD project aimed to identify minimum standards for the design of a COS study agreed upon by an international group, while other specific guidance exists for the final reporting of COS development studies (Core Outcome Set-STAndards for Reporting [COS-STAR].An international group of experienced COS developers, methodologists, journal editors, potential users of COS (clinical trialists, systematic reviewers, and clinical guideline developers, and patient representatives produced the COS-STAD recommendations to help improve the quality of COS development and support the assessment of whether a COS had been developed using a reasonable approach. An open survey of experts generated an initial list of items, which was refined by a 2-round Delphi survey involving nearly 250 participants representing key stakeholder groups. Participants assigned importance ratings for each item using a 1-9 scale. Consensus that an item should be included in the set of minimum standards was defined as at least 70% of the voting participants from each stakeholder group providing a score between 7 and 9. The Delphi survey was followed by a consensus discussion with the study management group representing multiple stakeholder groups. COS-STAD contains 11 minimum standards that are the minimum design recommendations for all COS development projects. The recommendations focus on 3 key domains: the scope, the stakeholders, and the consensus process.The COS-STAD project has established 11 minimum standards to be followed by COS developers when planning their projects and by users when deciding whether a COS has been developed using

  14. Genetics of cosQ, the DNA-packaging termination site of phage lambda: local suppressors and methylation effects.

    OpenAIRE

    Wieczorek, Douglas J; Feiss, Michael

    2003-01-01

    The cos site of the bacteriophage lambda chromosome contains the sites required for DNA processing and packaging during virion assembly. cos is composed of three subsites, cosQ, cosN, and cosB. cosQ is required for the termination of chromosome packaging. Previous studies have shown cosQ mutations to be suppressed in three ways: by a local suppressor within cosQ; by an increase in the length of the lambda chromosome; and by missense mutations affecting the prohead's portal protein, gpB. In th...

  15. In silico mapping of Conserved Ortholog Set (COS) markers in the potato genome

    Science.gov (United States)

    Conserved ortholog set (COS) markers are useful for genetic mapping across diverse taxa, including the Solanaceae. We amplified over 300 COS markers from diverse set of Solanum germplasm, sequenced them and aligned into the whole genome sequence of potato. We also mapped a set of COS markers genetic...

  16. Noninvasive optical diagnosis of low back pain with the aid of Chinese cupping procedure

    Science.gov (United States)

    Li, Nanxi; Li, Ting

    2018-02-01

    Low back pain (LBP) is a complex disease that can be cause by a variety of reasons. Now LBP has become a very common and severe disease among kinds of occupational groups with showing a younger trend. The traditional diagnosis relies on complicated imaging modalities and other dangerous and invasive methods. Noninvasive near-infrared spectroscopy (NIRS) is noninvasive and convenient, and has been successful used in point-of-care diagnosis. Here, we attempt to explore NIRS's application in in low back pain diagnosis and the effect of aid-use of Chinese cupping procedure. 13 LBP patients and 13 healthy subjects participated in NIRS measurements of concentrations of oxy- and deoxy-hemoglobins (Δ[HbO2] and Δ[Hb]) at the middle of the lumbar spine. It was showed that there was significant differences (p < 0.001) between healthy subjects and LBP patients after cupping procedure, while insignificant before cupping. Moreover, it was found that healthy subjects showed stronger responses to cupping procedure than LBP patients, with prominently higher concentration of Δ[HbO2] and Δ[Hb]. It indicates the potential of NIRS in noninvasive, measurable and straightforward monitoring/therapeutic effect evaluation of LBP with bedside and point-of-care monitoring capability.

  17. Assessment of Retinal and Choroidal Measurements in Chinese School-Age Children with Cirrus-HD Optical Coherence Tomography.

    Directory of Open Access Journals (Sweden)

    Tao Li

    Full Text Available To evaluate retinal thickness (RT, retinal volume (RV and choroidal thickness (ChT in Chinese children using Cirrus-HD optical coherence tomography (OCT, and assess their associations with spherical equivalent (SE, age and gender.This was a prospective study that recruited 193 healthy Chinese children (193 eyes with no ophthalmic disease history between December 2012 and December 2013. RT and RV were acquired using OCT. Subfoveal ChT (SFCT and ChT1-mm and 2-mm temporal, nasal, superior and inferior to the fovea were measured manually.RT in the inner temporal and nasal regionsdiffered significantly between refraction groups (both P<0.05. Significant differences were also found inSFCT andChT 1- and 2-mm inferior to the fovea (all P<0.05. RT differed significantly between males and females in the outer superior region in the emmetropia group (P<0.05. ChT differed significantly between males and females 2-mm temporal to the fovea in the emmetropia group (P<0.05, and 1-mm temporal to the fovea in the mild myopia group (P<0.05. SE correlated positively with RT in the inner temporal (r = 0.230,nasal (r = 0.252 and inferior (r = 0.149 regions (all P<0.05. Age correlated positively with foveolar (r = 0.169, total macular (r = 0.202, inner temporal (r = 0.237, inner nasal (r = 0.248, inner superior (r = 0.378 and inner inferior (r = 0.345 region thicknesses, and with RV (r = 0.207(all P<0.05. SE correlated positively with SFCT (r = 0.195, and with ChT1-mm temporal (r = 0.167, 1- and 2-mm nasal (r = 0.144 and r = 0.162, 2-mm superior (r = 0.175, and 1- and 2-mm inferior (r = 0.207 and r = 0.238 to the fovea (all P<0.05. Age had no significant association with ChT.SE, age and gender did not influence macular RT and ChT in most regions, and correlations of RT with age and ChT with SE were weak.

  18. Convergent evolution of pathogenicity islands in helper cos phage interference.

    Science.gov (United States)

    Carpena, Nuria; Manning, Keith A; Dokland, Terje; Marina, Alberto; Penadés, José R

    2016-11-05

    Staphylococcus aureus pathogenicity islands (SaPIs) are phage satellites that exploit the life cycle of their helper phages for their own benefit. Most SaPIs are packaged by their helper phages using a headful (pac) packaging mechanism. These SaPIs interfere with pac phage reproduction through a variety of strategies, including the redirection of phage capsid assembly to form small capsids, a process that depends on the expression of the SaPI-encoded cpmA and cpmB genes. Another SaPI subfamily is induced and packaged by cos-type phages, and although these cos SaPIs also block the life cycle of their inducing phages, the basis for this mechanism of interference remains to be deciphered. Here we have identified and characterized one mechanism by which the SaPIs interfere with cos phage reproduction. This mechanism depends on a SaPI-encoded gene, ccm, which encodes a protein involved in the production of small isometric capsids, compared with the prolate helper phage capsids. As the Ccm and CpmAB proteins are completely unrelated in sequence, this strategy represents a fascinating example of convergent evolution. Moreover, this result also indicates that the production of SaPI-sized particles is a widespread strategy of phage interference conserved during SaPI evolution.This article is part of the themed issue 'The new bacteriology'. © 2016 The Authors.

  19. Soil fluxes of carbonyl sulfide (COS), carbon monoxide, and carbon dioxide in a boreal forest in southern Finland

    NARCIS (Netherlands)

    Sun, Wu; Kooijmans, Linda M. J.; Maseyk, Kadmiel; Chen, Huilin; Mammarella, Ivan; Vesala, Timo; Levula, Janne; Keskinen, Helmi; Seibt, Ulli

    2018-01-01

    Soil is a major contributor to the biosphere-atmosphere exchange of carbonyl sulfide (COS) and carbon monoxide (CO). COS is a tracer with which to quantify terrestrial photosynthesis based on the coupled leaf uptake of COS and CO2, but such use requires separating soil COS flux, which is unrelated

  20. Investigations into the carbonic anhydrase inhibition of COS-releasing donor core motifs.

    Science.gov (United States)

    Steiger, Andrea K; Zhao, Yu; Choi, Won Jin; Crammond, Alder; Tillotson, McKinna R; Pluth, Michael D

    2018-03-01

    Carbonyl sulfide (COS) releasing scaffolds are gaining popularity as hydrogen sulfide (H 2 S) donors through exploitation of the carbonic anhydrase (CA)-mediated hydrolysis of COS to H 2 S. The majority of compounds in this emerging class of donors undergo triggerable decomposition (often referred to as self-immolation) to release COS, and a handful of different COS-releasing structures have been reported. One benefit of this donation strategy is that numerous caged COS-containing core motifs are possible and are poised for development into self-immolative COS/H 2 S donors. Because the intermediate release of COS en route to H 2 S donation requires CA, it is important that the COS donor motifs do not inhibit CA directly. In this work, we investigate the cytotoxicity and CA inhibition properties of different caged COS donor cores, as well as caged CO 2 and CS 2 motifs and non-self-immolative control compounds. None of the compounds investigated exhibited significant cytotoxicity or enhanced cell proliferation at concentrations up to 100 μM in A549 cells, but we identified four core structures that function as CA inhibitors, thus providing a roadmap for the future development of self-immolative COS/H 2 S donor motifs. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Relationships between carbonyl sulfide (COS) and CO2 during leaf gas exchange.

    Science.gov (United States)

    Stimler, Keren; Montzka, Stephen A; Berry, Joseph A; Rudich, Yinon; Yakir, Dan

    2010-06-01

    *Carbonyl sulfide (COS) exchange in C(3) leaves is linked to that of CO(2), providing a basis for the use of COS as a powerful tracer of gross CO(2) fluxes between plants and the atmosphere, a critical element in understanding the response of the land biosphere to global change. *Here, we carried out controlled leaf-scale gas-exchange measurements of COS and CO(2) in representative C(3) plants under a range of light intensities, relative humidities and temperatures, CO(2) and COS concentrations, and following abscisic acid treatments. *No 'respiration-like' emission of COS or detectable compensation point, and no cross-inhibition effects between COS and CO(2) were observed. The mean ratio of COS to CO(2) assimilation flux rates, A(s)/A(c), was c. 1.4 pmol micromol(-1) and the leaf relative uptake (assimilation normalized to ambient concentrations, (A(s)/A(c))(C(a)(c)/C(a)(s))) was 1.6-1.7 across species and conditions, with significant deviations under certain conditions. Stomatal conductance was enhanced by increasing COS, which was possibly mediated by hydrogen sulfide (H(2)S) produced from COS hydrolysis, and a correlation was observed between A(s) and leaf discrimination against C(18)OO. *The results provide systematic and quantitative information necessary for the use of COS in photosynthesis and carbon-cycle research on the physiological to global scales.

  2. Carbonyl sulfide (COS) as a tracer for canopy photosynthesis, transpiration and stomatal conductance: potential and limitations.

    Science.gov (United States)

    Wohlfahrt, Georg; Brilli, Federico; Hörtnagl, Lukas; Xu, Xiaobin; Bingemer, Heinz; Hansel, Armin; Loreto, Francesco

    2012-04-01

    The theoretical basis for the link between the leaf exchange of carbonyl sulfide (COS), carbon dioxide (CO(2)) and water vapour (H(2)O) and the assumptions that need to be made in order to use COS as a tracer for canopy net photosynthesis, transpiration and stomatal conductance, are reviewed. The ratios of COS to CO(2) and H(2)O deposition velocities used to this end are shown to vary with the ratio of the internal to ambient CO(2) and H(2)O mole fractions and the relative limitations by boundary layer, stomatal and internal conductance for COS. It is suggested that these deposition velocity ratios exhibit considerable variability, a finding that challenges current parameterizations, which treat these as vegetation-specific constants. COS is shown to represent a better tracer for CO(2) than H(2)O. Using COS as a tracer for stomatal conductance is hampered by our present poor understanding of the leaf internal conductance to COS. Estimating canopy level CO(2) and H(2)O fluxes requires disentangling leaf COS exchange from other ecosystem sources/sinks of COS. We conclude that future priorities for COS research should be to improve the quantitative understanding of the variability in the ratios of COS to CO(2) and H(2)O deposition velocities and the controlling factors, and to develop operational methods for disentangling ecosystem COS exchange into contributions by leaves and other sources/sinks. To this end, integrated studies, which concurrently quantify the ecosystem-scale CO(2), H(2)O and COS exchange and the corresponding component fluxes, are urgently needed. © 2011 Blackwell Publishing Ltd.

  3. Virtual half-metallicity at the CoS2/FeS2 interface induced by strain

    KAUST Repository

    Nazir, Safdar

    2013-01-01

    Spin polarized ab initio calculations based on density functional theory are performed to investigate the electronic and magnetic properties of the interface between the ferromagnetic metal CoS2 and the nonmagnetic semiconductor FeS2. Relaxation of the interface structure is taken into account by atomic force minimization. We find that both Co and Fe are close to half-metallicity at the interface. Tensile strain is shown to strongly enhance the spin polarization so that a virtually half-metallic interface can be achieved, for comparably moderate strain. © 2012 The Royal Society of Chemistry.

  4. Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.

    Science.gov (United States)

    Jaime, Maria D L A; Lopez-Llorca, Luis Vicente; Conesa, Ana; Lee, Anna Y; Proctor, Michael; Heisler, Lawrence E; Gebbia, Marinella; Giaever, Guri; Westwood, J Timothy; Nislow, Corey

    2012-06-22

    Chitosan oligosaccharide (COS), a deacetylated derivative of chitin, is an abundant, and renewable natural polymer. COS has higher antimicrobial properties than chitosan and is presumed to act by disrupting/permeabilizing the cell membranes of bacteria, yeast and fungi. COS is relatively non-toxic to mammals. By identifying the molecular and genetic targets of COS, we hope to gain a better understanding of the antifungal mode of action of COS. Three different chemogenomic fitness assays, haploinsufficiency (HIP), homozygous deletion (HOP), and multicopy suppression (MSP) profiling were combined with a transcriptomic analysis to gain insight in to the mode of action and mechanisms of resistance to chitosan oligosaccharides. The fitness assays identified 39 yeast deletion strains sensitive to COS and 21 suppressors of COS sensitivity. The genes identified are involved in processes such as RNA biology (transcription, translation and regulatory mechanisms), membrane functions (e.g. signalling, transport and targeting), membrane structural components, cell division, and proteasome processes. The transcriptomes of control wild type and 5 suppressor strains overexpressing ARL1, BCK2, ERG24, MSG5, or RBA50, were analyzed in the presence and absence of COS. Some of the up-regulated transcripts in the suppressor overexpressing strains exposed to COS included genes involved in transcription, cell cycle, stress response and the Ras signal transduction pathway. Down-regulated transcripts included those encoding protein folding components and respiratory chain proteins. The COS-induced transcriptional response is distinct from previously described environmental stress responses (i.e. thermal, salt, osmotic and oxidative stress) and pre-treatment with these well characterized environmental stressors provided little or any resistance to COS. Overexpression of the ARL1 gene, a member of the Ras superfamily that regulates membrane trafficking, provides protection against COS

  5. Biotechnological approaches for field applications of chitooligosaccharides (COS) to induce innate immunity in plants.

    Science.gov (United States)

    Das, Subha Narayan; Madhuprakash, Jogi; Sarma, P V S R N; Purushotham, Pallinti; Suma, Katta; Manjeet, Kaur; Rambabu, Samudrala; Gueddari, Nour Eddine El; Moerschbacher, Bruno M; Podile, Appa Rao

    2015-03-01

    Plants have evolved mechanisms to recognize a wide range of pathogen-derived molecules and to express induced resistance against pathogen attack. Exploitation of induced resistance, by application of novel bioactive elicitors, is an attractive alternative for crop protection. Chitooligosaccharide (COS) elicitors, released during plant fungal interactions, induce plant defenses upon recognition. Detailed analyses of structure/function relationships of bioactive chitosans as well as recent progress towards understanding the mechanism of COS sensing in plants through the identification and characterization of their cognate receptors have generated fresh impetus for approaches that would induce innate immunity in plants. These progresses combined with the application of chitin/chitosan/COS in disease management are reviewed here. In considering the field application of COS, however, efficient and large-scale production of desired COS is a challenging task. The available methods, including chemical or enzymatic hydrolysis and chemical or biotechnological synthesis to produce COS, are also reviewed.

  6. Cycle 24 COS NUV Internal/External Wavelength Scale Monitor

    Science.gov (United States)

    Fischer, William J.

    2018-02-01

    We report on the monitoring of the COS NUV wavelength scale zero-points during Cycle 24 in program 14859. Select cenwaves were monitored for all NUV gratings. The target and cenwaves have remained the same since Cycle 18, with changes only to the target acquisition sequence and the number of visits per cycle. With minor exceptions, measured offsets are within the error goals. The declining sensitivity of the G285M grating is beginning to present a challenge for precise cross-correlation.

  7. Cycle 24 COS FUV Internal/External Wavelength Scale Monitor

    Science.gov (United States)

    Fischer, William J.

    2018-02-01

    We report on the monitoring of the COS FUV wavelength scale zero-points during Cycle 24 in program 14855. Select cenwaves were monitored for all FUV gratings at Lifetime Position 3. The target and cenwaves have remained the same since Cycle 21, with a change only to the target acquisition sequence. All measured offsets are within the error goals, although the G140L cenwaves show offsets at the short-wavelength end of segment A that are approaching the tolerance. This behavior will be closely monitored in subsequent iterations of the program.

  8. Towards the understanding of biogeochemical processes involved in the release of carbonyl sulfide (COS) from soil

    Science.gov (United States)

    Behrendt, Thomas; Catao, Elisa; Bunk, Rüdiger; Yi, Zhigang; Greule, Markus; Keppler, Frank; Kesselmeier, Jürgen; Trumbore, Susan

    2017-04-01

    Carbonyl sulfide (COS) is present in the atmosphere in low mixing ratio ( 500ppt). It is relevant in climate change through the effect in aerosol formation. Soils can act as source of COS, e.g. by microbial degradation of thiocyanate from plant material. On the other side it is known that COS can be consumed via various enzymatic pathways. Assuming that biogenic processes dominate over chemical reactions we extracted nucleic acids and performed amplicon sequencing for bacteria (16S rRNA) and fungi (ITS region) from a mid-latitude agricultural maize soil which was previously incubated under ambient COS and COS fumigation ( 1000ppt). The mixing ratios of COS have been measured online from soil samples in a dynamic chamber system under laboratory conditions by an integrated cavity output spectroscopy (IOCS) analyzer (Los Gatos Research Inc., USA). Additionally stable carbon isotope values (δ13C values) of COS were measured using a pre-concentration method and stable isotope ratio mass spectrometry (IRMS). Under low COS mixing ratio ( 50ppt) δ13C +4.7 ‰ for spruce forest ( 23°C), and -24.4‰ for mid-latitude cornfield ( 22°C), respectively. Linking gas release rates of (COS, CO2, CO, NO) to isotopic signatures of COS and molecular results might allow us to indicate bacterial s-compound degradation related to the higher activity of β-Proteobacteria and of the family Acetobacteraceae from the α-Proteobacteria phylum, potentially involved with the hydrolysis of thiocyanate in the soil releasing COS. Furthermore, our study reports the first COS data for rainforest and desert soils which are in the order of 0.5 pmol gdw-1 h-1 and 2 pmol gdw-1 h-1, respectively.

  9. COS-STAR: a reporting guideline for studies developing core outcome sets (protocol).

    Science.gov (United States)

    Kirkham, Jamie J; Gorst, Sarah; Altman, Douglas G; Blazeby, Jane; Clarke, Mike; Devane, Declan; Gargon, Elizabeth; Williamson, Paula R

    2015-08-22

    Core outcome sets can increase the efficiency and value of research and, as a result, there are an increasing number of studies looking to develop core outcome sets (COS). However, the credibility of a COS depends on both the use of sound methodology in its development and clear and transparent reporting of the processes adopted. To date there is no reporting guideline for reporting COS studies. The aim of this programme of research is to develop a reporting guideline for studies developing COS and to highlight some of the important methodological considerations in the process. The study will include a reporting guideline item generation stage which will then be used in a Delphi study. The Delphi study is anticipated to include two rounds. The first round will ask stakeholders to score the items listed and to add any new items they think are relevant. In the second round of the process, participants will be shown the distribution of scores for all stakeholder groups separately and asked to re-score. A final consensus meeting will be held with an expert panel and stakeholder representatives to review the guideline item list. Following the consensus meeting, a reporting guideline will be drafted and review and testing will be undertaken until the guideline is finalised. The final outcome will be the COS-STAR (Core Outcome Set-STAndards for Reporting) guideline for studies developing COS and a supporting explanatory document. To assess the credibility and usefulness of a COS, readers of a COS development report need complete, clear and transparent information on its methodology and proposed core set of outcomes. The COS-STAR guideline will potentially benefit all stakeholders in COS development: COS developers, COS users, e.g. trialists and systematic reviewers, journal editors, policy-makers and patient groups.

  10. Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS using chemogenomics

    Directory of Open Access Journals (Sweden)

    Jaime Maria DLA

    2012-06-01

    Full Text Available Abstract Background Chitosan oligosaccharide (COS, a deacetylated derivative of chitin, is an abundant, and renewable natural polymer. COS has higher antimicrobial properties than chitosan and is presumed to act by disrupting/permeabilizing the cell membranes of bacteria, yeast and fungi. COS is relatively non-toxic to mammals. By identifying the molecular and genetic targets of COS, we hope to gain a better understanding of the antifungal mode of action of COS. Results Three different chemogenomic fitness assays, haploinsufficiency (HIP, homozygous deletion (HOP, and multicopy suppression (MSP profiling were combined with a transcriptomic analysis to gain insight in to the mode of action and mechanisms of resistance to chitosan oligosaccharides. The fitness assays identified 39 yeast deletion strains sensitive to COS and 21 suppressors of COS sensitivity. The genes identified are involved in processes such as RNA biology (transcription, translation and regulatory mechanisms, membrane functions (e.g. signalling, transport and targeting, membrane structural components, cell division, and proteasome processes. The transcriptomes of control wild type and 5 suppressor strains overexpressing ARL1, BCK2, ERG24, MSG5, or RBA50, were analyzed in the presence and absence of COS. Some of the up-regulated transcripts in the suppressor overexpressing strains exposed to COS included genes involved in transcription, cell cycle, stress response and the Ras signal transduction pathway. Down-regulated transcripts included those encoding protein folding components and respiratory chain proteins. The COS-induced transcriptional response is distinct from previously described environmental stress responses (i.e. thermal, salt, osmotic and oxidative stress and pre-treatment with these well characterized environmental stressors provided little or any resistance to COS. Conclusions Overexpression of the ARL1 gene, a member of the Ras superfamily that regulates membrane

  11. Effects of carbonyl sulfide (COS) and carbonic anhydrase on stomatal conductance

    Science.gov (United States)

    Yakir, D.; Stimler, K.; Berry, J. A.

    2011-12-01

    The potential use of COS as tracer of the gross, one-way, CO2 flux into plants is based on its co-diffusion with CO2 into leaves without outflux stimulated research on COS-CO2 interactions during leaf gas exchange. We carried out gas exchange measurements of COS and CO2 in 22 plant species representing deciduous and evergreen trees, grasses, and shrubs, under a range of light intensities and ambient COS concentrations, using mid IR laser spectroscopy. A narrow range in the normalized ratio of the net uptake rates of COS (As) and CO2 (Ac; As/Ac*[CO2]/[COS]) was observed, with a mean value of 1.61±0.26. These results reflect the dominance of stomatal conductance over both COS and CO2 uptake, imposing a relatively constant ratio between the two fluxes (except under low light conditions when CO2, but not COS, metabolism is light limited). A relatively constant ratio under common ambient conditions will facilitate the application of COS as a tracer of gross photosynthesis from leaf to global scales. However, its effect on stomatal conductance may require a special attention. Increasing COS concentrations between 250 and 2800 pmol mol-1 (enveloping atmospheric levels) seems to stimulate stomatal conductance. We examined the stimulation of conductance by COS in a range of species and show that there is a large variation with some species showing almost no response while others are highly responsive (up to doubling stomatal conductance). Using C3 and C4 plants with antisense lines abolishing carbonic anhydrase activity, we show that the activity of this enzyme is essential for both the uptake of COS and the enhancement of stomatal conductance by COS. Since carbonic anhydrase catalyzes the conversion of COS to CO2 and H2S it seems likely that the stomata are responding to H2S produced in the mesophyll. In all natural species examined the uptake of COS and CO2 were highly correlated, and there was no relationship between the sensitivity of stomata and the rate of COS uptake

  12. Divergent distribution of the sensor kinase CosS in non-thermotolerant campylobacter species and its functional incompatibility with the response regulator CosR of Campylobacter jejuni.

    Directory of Open Access Journals (Sweden)

    Sunyoung Hwang

    Full Text Available Two-component signal transduction systems are commonly composed of a sensor histidine kinase and a cognate response regulator, modulating gene expression in response to environmental changes through a phosphorylation-dependent process. CosR is an OmpR-type response regulator essential for the viability of Campylobacter jejuni, a major foodborne pathogenic species causing human gastroenteritis. Although CosR is a response regulator, its cognate sensor kinase has not been identified in C. jejuni. In this study, DNA sequence analysis of the cosR flanking regions revealed that a gene encoding a putative sensor kinase, which we named cosS, is prevalent in non-thermotolerant Campylobacter spp., but not in thermotolerant campylobacters. Phosphorylation assays indicated that C. fetus CosS rapidly autophosphorylates and then phosphorylates C. fetus CosR, suggesting that the CosRS system constitutes a paired two-component signal transduction system in C. fetus. However, C. fetus CosS does not phosphorylate C. jejuni CosR, suggesting that CosR may have different regulatory cascades between thermotolerant and non-thermotolerant Campylobacter species. Comparison of CosR homolog amino acid sequences showed that the conserved phosphorylation residue (D51, which is present in all non-thermotolerant Campylobacter spp., is absent from the CosR homologs of thermotolerant Campylobacter species. However, C. jejuni CosR was not phosphorylated by C. fetus CosS even after site-directed mutagenesis of N51D, implying that C. jejuni CosR may possibly function phosphorylation-independently. In addition, the results of cosS mutational analysis indicated that CosS is not associated with the temperature dependence of the Campylobacter spp. despite its unique divergent distribution only in non-thermotolerant campylobacters. The findings in this study strongly suggest that thermotolerant and non-thermotolerant Campylobacter spp. have different signal sensing mechanisms

  13. Mutation screening of mitochondrial DNA as well as OPA1 and OPA3 in a Chinese cohort with suspected hereditary optic atrophy.

    Science.gov (United States)

    Chen, Jieqiong; Xu, Ke; Zhang, Xiaohui; Jiang, Feng; Liu, Lijuan; Dong, Bing; Ren, Yanfan; Li, Yang

    2014-09-09

    Leber's hereditary optic atrophy (LHON) and autosomal dominant optic atrophy (DOA) are the two most common forms. The objective of this study was to define the fractional prevalence of LHON and DOA in a cohort of Chinese patients with suspected hereditary optic neuropathy. We recruited 520 unrelated patients with bilateral optic atrophy for genetic analysis: 174 patients had a positive family history of visual failure and 346 were sporadic cases. A total of 14 primary LHON-causing mtDNA mutations was screened by PCR-based sequencing methods for all patients except the individuals with a paternal family history. All coding exons and exon-intron boundaries of the OPA1 and OPA3 gene were screened for mutations by PCR-based DNA sequencing for all patients with paternal family history and for the LHON-negative patients. A large genomic DNA arrangement of the OPA1 gene was detected further by multiplex ligation probe amplification (MLPA) assay for the patients with paternal family history, but results were negative for the OPA1 and OPA3 mutation screenings. We found molecular defects in 323 (62%) of the 520 probands screened. Among these, 271 patients (83.9%) had an mtDNA mutation, 50 patients (15.5%) carried an OPA1 mutation, and 2 patients (0.6%) had an OPA3 mutation. Coexistence m.3460 G>A and m.11778G>A was found in one patient. We identified 40 intragenic mutations and six large genomic DNA arrangements of the OPA1 gene, 23 of which were novel. The LHON-mtDNA mutations are the most common genetic defects, followed by the OPA1 mutations, in this Chinese cohort. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  14. Investigation of MEK activity in COS7 cells entering mitosis.

    Science.gov (United States)

    Shi, Huaiping; Zhang, Tianying; Yi, Yongqing; Luo, Jun

    2014-12-01

    Although the mitogen-activated protein kinase (MAPK) pathway has been extensively investigated, numerous events remain unclear. In the present study, we examined mitogen-activated protein kinase kinase (MEK) expression from interphase to mitosis. Following nocodazole treatment, COS7 cells gradually became round as early as 4 h after treatment. Cyclin B1 expression gradually increased from 4 to 24 h in the presence of nocodazole. When cells were treated with nocodazole for 4 h, the level of epidermal growth factor (EGF)-mediated MEK phosphorylation did not significantly change between nocodazole-untreated and -treated (4 h) cells (P>0.05). However, EGF-mediated MEK phosphorylation was significantly inhibited upon treatment with nocodazole for 8 and 24 h compared to nocodazole-untreated cells (PMEK phosphorylation levels were comparable between 1, 5, 10 and 50 ng/ml EGF treatments. Phorbol 12-myristic 13-acetate (PMA) did not activate MEK in mitotic cells. Following treatment of COS7 cells at the interphase with AG1478 or U0126, MEK phosphorylation was blocked. In addition, the investigation of the expression of proteins downstream of MEK demonstrated that EGF does not significantly affect the phosphorylation level of extracellular-signal-regulated kinase (ERK), ribosomal protein S6 kinase (RSK) and Elk in mitotic cells (P>0.05). The results showed that MEK expression is gradually inhibited from cell interphase to mitosis, and that MEK downstream signaling is affected by this inhibition, which probably reflects the requirements of cell physiology during mitosis.

  15. Aerosol optical properties observation and its relationship to meteorological conditions and emission during the Chinese National Day and Spring Festival holiday in Beijing

    Science.gov (United States)

    Zheng, Yu; Che, Huizheng; Zhao, Tianliang; Zhao, Hujia; Gui, Ke; Sun, Tianze; An, Linchang; Yu, Jie; Liu, Chong; Jiang, Yongcheng; Zhang, Lei; Wang, Hong; Wang, Yaqiang; Zhang, Xiaoye

    2017-11-01

    The reduction of traffic flow in downtown areas during the Chinese National Day holiday and the fireworks during the Spring Festival provide a unique opportunity for investigating the impact of urban anthropogenic activities on aerosol optical properties during these important Chinese festivals in Beijing. The National Day in 2014 and 2015 and Spring Festival in 2015 and 2016 were selected as study periods. The aerosol optical depth (AOD) at 440 nm increased over the all holiday periods and the average AODs during the 2015 National Day, 2015 Spring Festival and 2016 Spring Festival were about 81%, 21% and 36% higher than the background levels, respectively. The average AOD in 2014 National Day holiday was lower than background level partly influenced by precipitation event. The absorption AOD (AAOD) at 440 nm showed consistent variations with the AOD and the average AAODs during the 2015 National Day, 2015 Spring Festival and 2016 Spring Festival holidays were about 75%, 19% and 23% higher than the background level, respectively. The mean values of single scattering albedo were greater than the background level during the Spring Festival holidays, whereas the values during the National Day holiday in 2015 were lower partly due to the reduction of vehicular emissions in downtown areas. Fine- and coarse-mode particle volumes during pollution periods in holidays were 0.04-0.25 μm3 and 0.03-0.15 μm3 larger than background level, respectively. The results of potential source contribution function and concentration-weighted trajectory analyses identified the areas south of Beijing as the main source regions of PM2.5 and were responsible for the extremely high PM2.5 concentrations in Beijing during the holiday periods. The findings of this study may aid understanding the effects of human activities on aerosol optical properties over Beijing area and contribute to improving regional air quality.

  16. Kinetic study of COS with tertiary alkanolamine solutions 1. Experiments in an intensely stirred batch reactor

    NARCIS (Netherlands)

    Littel, R.J.; Littel, R.J.; Versteeg, Geert; van Swaaij, Willibrordus Petrus Maria

    1992-01-01

    The reaction between COS and various tertiary alkanolamines in aqueous solutions has been studied in an intensely stirred batch reactor. Experiments for TEA, DMMEA, and DEMEA were carried out at 303 K the reaction between COS and aqueous MDEA has been studied at temperaturm ranging from 293 to 323

  17. Kinetic Study of COS with Tertiary Alkanolamine Solutions. 1. Experiments in an Intensely Stirred Batch Reactor

    NARCIS (Netherlands)

    Littel, Rob J.; Versteeg, Geert F.; Swaaij, Wim P.M. van

    1992-01-01

    The reaction between COS and various tertiary alkanolamines in aqueous solutions has been studied in an intensely stirred batch reactor. Experiments for TEA, DMMEA, and DEMEA were carried out at 303 K; the reaction between COS and aqueous MDEA has been studied at temperatures ranging from 293 to 323

  18. 76 FR 24843 - Safety Zone; Rudey/Braga Wedding Fireworks Display, Cos Cob Harbor, Greenwich, CT

    Science.gov (United States)

    2011-05-03

    ...-AA00 Safety Zone; Rudey/Braga Wedding Fireworks Display, Cos Cob Harbor, Greenwich, CT AGENCY: Coast... of a wedding celebration in Greenwich, CT, directly off a private estate in Cos Cob Harbor. This rule.... 0170.1. 2. Add Sec. 165.T01-0148 to read as follows: Sec. 165.T01-0148 Safety Zone; Rudey/Braga Wedding...

  19. Optics

    CERN Document Server

    Mathieu, Jean Paul

    1975-01-01

    Optics, Parts 1 and 2 covers electromagnetic optics and quantum optics. The first part of the book examines the various of the important properties common to all electromagnetic radiation. This part also studies electromagnetic waves; electromagnetic optics of transparent isotropic and anisotropic media; diffraction; and two-wave and multi-wave interference. The polarization states of light, the velocity of light, and the special theory of relativity are also examined in this part. The second part is devoted to quantum optics, specifically discussing the classical molecular theory of optical p

  20. Galaxy Groups in HST/COS-SDSS Fields

    Science.gov (United States)

    Conway, Matthew; Hamill, Colin; Apala, Elizabeth; Scott, Jennifer

    2018-01-01

    We extend the results of a study of the sightlines of 45 low redshift quasars (0.06 footprint of the Sloan Digital Sky Survey. We have used photometric data from the SDSS DR12, along with the known absorption characteristics of the intergalactic medium and circumgalactic medium, to identify the most probable galaxy matches to absorbers in the spectroscopic dataset. Here, we use an existing catalog of galaxy group candidates in the SDSS DR8 to identify galaxy groups within our HST/COS-SDSS fields that may show line of sight absorption due to an intergroup medium. To identify galaxy group candidates that lie within the impact parameter of our quasar fields (< 3 degrees), we calculate the angular separation between the quasar coordinates and the galaxy group centroid coordinates. We investigate differences in galaxy and absorber properties among the galaxy-absorber pairs likely arising in groups and those likely associated with individual field galaxies.

  1. Chinese student mobility, local engagement and transformation of Chinese communities in England: an empirical study

    OpenAIRE

    Wu, Bin

    2016-01-01

    Unprecedented growth and circulation of Chinese international students cannot be fully understood unless the roles of host societies including diaspora Chinese communities are taken into account. This chapter draws attention to a phenomenon of local engagement, a process of interconnections and interactions between Chinese students and local communities, leading to a co-development of both Chinese students and diaspora Chinese communities in host countries. The links and impacts of Chinese st...

  2. Optics

    CERN Document Server

    Fincham, W H A

    2013-01-01

    Optics: Ninth Edition Optics: Ninth Edition covers the work necessary for the specialization in such subjects as ophthalmic optics, optical instruments and lens design. The text includes topics such as the propagation and behavior of light; reflection and refraction - their laws and how different media affect them; lenses - thick and thin, cylindrical and subcylindrical; photometry; dispersion and color; interference; and polarization. Also included are topics such as diffraction and holography; the limitation of beams in optical systems and its effects; and lens systems. The book is recommen

  3. Soil fluxes of carbonyl sulfide (COS), carbon monoxide, and carbon dioxide in a boreal forest in southern Finland

    Science.gov (United States)

    Sun, Wu; Kooijmans, Linda M. J.; Maseyk, Kadmiel; Chen, Huilin; Mammarella, Ivan; Vesala, Timo; Levula, Janne; Keskinen, Helmi; Seibt, Ulli

    2018-02-01

    Soil is a major contributor to the biosphere-atmosphere exchange of carbonyl sulfide (COS) and carbon monoxide (CO). COS is a tracer with which to quantify terrestrial photosynthesis based on the coupled leaf uptake of COS and CO2, but such use requires separating soil COS flux, which is unrelated to photosynthesis, from ecosystem COS uptake. For CO, soil is a significant natural sink that influences the tropospheric CO budget. In the boreal forest, magnitudes and variabilities of soil COS and CO fluxes remain poorly understood. We measured hourly soil fluxes of COS, CO, and CO2 over the 2015 late growing season (July to November) in a Scots pine forest in Hyytiälä, Finland. The soil acted as a net sink of COS and CO, with average uptake rates around 3 pmol m-2 s-1 for COS and 1 nmol m-2 s-1 for CO. Soil respiration showed seasonal dynamics controlled by soil temperature, peaking at around 4 µmol m-2 s-1 in late August and September and dropping to 1-2 µmol m-2 s-1 in October. In contrast, seasonal variations of COS and CO fluxes were weak and mainly driven by soil moisture changes through diffusion limitation. COS and CO fluxes did not appear to respond to temperature variation, although they both correlated well with soil respiration in specific temperature bins. However, COS : CO2 and CO : CO2 flux ratios increased with temperature, suggesting possible shifts in active COS- and CO-consuming microbial groups. Our results show that soil COS and CO fluxes do not have strong variations over the late growing season in this boreal forest and can be represented with the fluxes during the photosynthetically most active period. Well-characterized and relatively invariant soil COS fluxes strengthen the case for using COS as a photosynthetic tracer in boreal forests.

  4. IAEA Syllabus for the Education and Training of Radiation Oncologists. Endorsed by the American Society for Radiation Oncology (ASTRO) and the European Society for Therapeutic Radiology and Oncology (ESTRO) (Chinese Edition)

    International Nuclear Information System (INIS)

    2014-01-01

    obstacle to making radiotherapy accessible to cancer patients. To ensure a uniformity and consistency in the training that could be undertaken by the various medical institutions running their postgraduate programmes in radiation oncology the IAEA's intent in formulating a syllabus for the education and training of radiation oncologists is to provide guidance for all professionals and administrators involved in the training of this discipline. The syllabus seeks to address the training requirements in developing countries in order to establish a common and consistent framework. It provides both a structure for the organization of the training and a core curriculum. The guidelines outlined in the core curriculum could be adopted by the various Member States as a baseline for national curricula. These guidelines have been framed via consultations with representatives of the Member States - both from developed and developing countries at a Consultants' Meeting held at IAEA headquarters in Vienna on 14-17 August 2006 and were commented on by major national and regional societies of radiation oncology. The IAEA recognizes the variability in the prevalence and spectrum of diseases as well as the variation in the availability of different technologies in the countries and regions. National and regional societies should prioritize the subjects presented in the core curriculum and adapt them to the disease profiles observed in their own countries/regions. Countries with a limited number of radiation oncologists should recognize the fact that cancer care is becoming ever more specialized and other aspects of cancer care such as medical oncology and palliative care should act in collaboration with the radiation oncologists to cover these other partially overlapping disciplines. The IAEA promotes a policy of multidisciplinary decision-making regarding the management of the individual patient, where the radiation oncologist interacts with other disciplines as a competent and

  5. COS2025: Extending the Lifetime of the FUV channel of the Cosmic Origins Spectrograph to 2025

    Science.gov (United States)

    Rafelski, Marc; De Rosa, Gisella; Fischer, William J.; Fix, Mees; Fox, Andrew; Indriolo, Nick; James, Bethan; Magness, Camellia; Oliveira, Cristina M.; Penton, Steven V.; Plesha, Rachel; Roman-Duval, Julia; Sahnow, David J.; Sankrit, Ravi; Snyder, Elaine M.; Taylor, Joanna M.; White, James

    2018-01-01

    The Hubble Space Telescope's Cosmic Origins Spectrograph (COS) Far-Ultraviolet (FUV) microchannel plate detector's efficiency at converting incoming photons into detectable events decreases with usage. This depletion of the detector's gain (i.e. gain sag) results in unusable regions of the COS/FUV detector. In order to mitigate this gain sag, a number of strategies have been employed over the past 8 years of operations, ranging from moving to different lifetime positions, to managing the high voltage to extract a smaller amount of charge, to re-distributing the cenwave usage so that Ly-alpha does not produce a gain-sag hole in a given location. We are now at a point where none of the strategies above will, without any other changes, allow us to continue operating the COS/FUV detector to 2025. To address this a new COS2025 policy was developed, with the goal of retaining full science capability of COS/FUV to 2025. We present an overview of the COS2025 policy, which places restrictions on the G130M cenwaves allowed at Lifetime Position 4 (LP4). We also present a tool which allows users to visualize the COS/FUV wavelength ranges to help users prepare their proposals in the light of the restrictions on the G130M cenwaves.

  6. LYVE-1 enhances the adhesion of HS-578T cells to COS-7 cells via hyaluronan.

    Science.gov (United States)

    Du, Yan; Liu, Yiwen; Wang, Yingzhi; He, Yiqing; Yang, Cuixia; Gao, Feng

    2011-02-01

    Lymphatic vessel endothelial hyaluronan receptor (LYVE-1), a specific molecular marker for lymph systems, has only one known ligand, hyaluronan (HA). Many studies have reported that HA, on the surface of tumor cells, is associated with the metastatic behavior of cancer cells. The interaction of LYVE-1 with HA may facilitate tumor cell attachment and enhance dissemination of tumor cells to lymph nodes. The aim of this study was to explore the biological function of LYVE-1 and to determine whether the interaction between LYVE-1 and HA was directly involved in the adhesion of tumor cells to lymphatic vessels. COS-7 cells were transfected with cDNA encoding LYVE-1 and expressed LYVE-1 assembled exogenously added HA. A high HA-expressing breast cancer cell line, HS-578T, was chosen to be the upper layer of cells that adhered to a lower layer of COS-7(LYVE-1(+)), COS-7(pEGFP-N1), or COS-7 cells for the adhesion analyses. The mechanism of adhesion was investigated by an experiment in which the HA on the surface of HS-578T cells was digested by Streptomyces hyaluronidase before the HS-578T cells were allowed to adhere to COS-7(LYVE-1(+)) cells. Results showed that more adhesion was observed between HS-578T and COS-7(LYVE-1(+)) cells, while less adhesion was observed between HS-578T cells and either COS-7(pEGFP-N1) or COS-7 cells (p COS-7(LYVE-1(+)) cells suggesting that this adhesion might be mediated through HA. Our results suggest that LYVE-1 allows the adhesion of tumor cells through the interaction of HA on the tumor cell membrane with LYVE-1.

  7. Expression of Cryptosporidium parvum thioredoxin peroxidase in COS-7 cells confers radioprotection.

    Science.gov (United States)

    Hong, Semie; Kim, Jae-Hwan; Yoon, Sejoung; Kim, Kyoungjin; Sim, Seobo; Park, Woo-Yoon; Yu, Jae-Ran

    2016-04-01

    Cryptosporidium parvum is one of the most radioresistant organisms identified to date. In a previous study, we found that thioredoxin peroxidase (CpTPx) was significantly upregulated in this species following exposure to high dose (10 kGy) of γ-irradiation. To assess the potential of CpTPx to confer radioprotection in mammalian cells, it was expressed in COS-7 African green monkey kidney cells (CpTPx-COS7). For comparison, the thioredoxin peroxidase of Cryptosporidium muris (CmTPx) was also expressed in these cells (CmTPx-COS7 cells), which has been confirmed to have lesser antioxidant activity than CpTPx in the previous study. Notably, the survival rates of CpTPx-COS7 cells were significantly higher (12-22%) at 72 h after 8 Gy irradiation than CmTPx-COS7 or non-transfected COS-7 (ntCOS-7) counterparts. In addition, CpTPx revealed a 50% of ROS reduction in irradiated CpTPx-COS7 cells, while γ-H2AX DNA damage marker expression was not significantly changed. Furthermore, the amount of apoptosis only increased to about 120% after 2-8 Gy irradiation compared to 200-300% increase observed in ntCOS-7 cells. CmTPx was shown to have antioxidant and DNA damage protection activities; however, these activities were always lower than those of CpTPx. These results suggest that the potent antioxidant and protective activities of CpTPx are well conserved in this cell-based system and that CpTPx contributed to the radioprotection of mammalian cells through its exceptional antioxidant activity. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Comparative analysis of the radish genome based on a conserved ortholog set (COS) of Brassica.

    Science.gov (United States)

    Jeong, Young-Min; Chung, Won-Hyong; Chung, Hee; Kim, Namshin; Park, Beom-Seok; Lim, Ki-Byung; Yu, Hee-Ju; Mun, Jeong-Hwan

    2014-09-01

    This manuscript provides a Brassica conserved ortholog set (COS) that can be used as diagnostic cross-species markers as well as tools for genetic mapping and genome comparison of the Brassicaceae. A conserved ortholog set (COS) is a collection of genes that are conserved in both sequence and copy number between closely related genomes. COS is a useful resource for developing gene-based markers and is suitable for comparative genome mapping. We developed a COS for Brassica based on proteome comparisons of Arabidopsis thaliana, B. rapa, and B. oleracea to establish a basis for comparative genome analysis of crop species in the Brassicaceae. A total of 1,194 conserved orthologous single-copy genes were identified from the genomes based on whole-genome BLASTP analysis. Gene ontology analysis showed that most of them encoded proteins with unknown function and chloroplast-related genes were enriched. In addition, 152 Brassica COS primer sets were applied to 16 crop and wild species of the Brassicaceae and 57.9-92.8 % of them were successfully amplified across the species representing that a Brassica COS can be used as diagnostic cross-species markers of diverse Brassica species. We constructed a genetic map of Raphanus sativus by analyzing the segregation of 322 COS genes in an F2 population (93 individuals) of Korean cultivars (WK10039 × WK10024). Comparative genome analysis based on the COS genes showed conserved genome structures between R. sativus and B. rapa with lineage-specific rearrangement and fractionation of triplicated subgenome blocks indicating close evolutionary relationship and differentiation of the genomes. The Brassica COS developed in this study will play an important role in genetic, genomic, and breeding studies of crop Brassicaceae species.

  9. In situ soil COS exchange of a temperate mountain grassland under simulated drought.

    Science.gov (United States)

    Kitz, Florian; Gerdel, Katharina; Hammerle, Albin; Laterza, Tamara; Spielmann, Felix M; Wohlfahrt, Georg

    2017-03-01

    During recent years, carbonyl sulfide (COS), a trace gas with a similar diffusion pathway into leaves as carbon dioxide (CO 2 ), but with no known "respiration-like" leaf source, has been discussed as a promising new approach for partitioning net ecosystem-scale CO 2 fluxes into photosynthesis and respiration. The utility of COS for flux partitioning at the ecosystem scale critically depends on the understanding of non-leaf sources and sinks of COS. This study assessed the contribution of the soil to ecosystem-scale COS fluxes under simulated drought conditions at temperate grassland in the Central Alps. We used transparent steady-state flow-through chambers connected to a quantum cascade laser spectrometer to measure the COS and CO 2 gas exchange between the soil surface and the atmosphere. Soils were a source of COS during the day, emissions being mainly driven by incoming solar radiation and to a lesser degree soil temperature. Soil water content had a negligible influence on soil COS exchange and thus the drought and control treatment were statistically not significantly different. Overall, daytime fluxes were large (12.5 ± 13.8 pmol m -2  s -1 ) in their magnitude and consistently positive compared to the previous studies, which predominantly used dark chambers. Nighttime measurements revealed soil COS fluxes around zero, as did measurements with darkened soil chambers during daytime reinforcing the importance of incoming solar radiation. Our results suggest that abiotic drivers play a key role in controlling in situ soil COS fluxes of the investigated grassland.

  10. Optics

    CERN Document Server

    Fincham, W H A

    2013-01-01

    Optics: Eighth Edition covers the work necessary for the specialization in such subjects as ophthalmic optics, optical instruments and lens design. The text includes topics such as the propagation and behavior of light; reflection and refraction - their laws and how different media affect them; lenses - thick and thin, cylindrical and subcylindrical; photometry; dispersion and color; interference; and polarization. Also included are topics such as diffraction and holography; the limitation of beams in optical systems and its effects; and lens systems. The book is recommended for engineering st

  11. Colloquium on Atomic, Molecular and Optical Physics of the French Physics Society. Days of Molecular Spectroscopy, Lille, 7-10 July 2008

    International Nuclear Information System (INIS)

    Balcou, Philippe; Aspect, Alain; Merkt, Frederic; Haroche, Serge; Hendecourt, Louis d'; Dereux, Alain; Bloch, Daniel; Courty, Jean-Michel; Demaison, Jean; Hynes, James T.; Lievin, Jacky; Billy, J.; Josse, V.; Zuo, Z.; Bernard, A.; Hambrecht, B.; Lugan, P.; Clement, D.; Sanchez-Palencia, L.; Bouyer, P.; Aspect, A.; Garreau, Jean-Claude; Chabe, Julien; Szriftgiser, Pascal; Lemarie, Gabriel; Gremaud, Benoit; Delande, Dominique; Simoni, Andrea; Browaeys, Antoine; Kasparian, Jerome; Boutou, Veronique; Guyon, Laurent; Courvoisier, Francois; Roth, Matthias; Roslund, Jon; Rabitz, Herschel; Bonacina, Luigi; Rondi, Ariana; Extermann, Jerome; Wolf, Jean-Pierre; Maitre, Philippe; Zehnacker, Anne; Le Barbu-Debus, Katia; Sidis, Victor; Aguillon, Francois; Sizun, Muriel; Rougeau, Nathalie; Teillet-Billy, Dominique; Bachellerie, Damien; Jeloaica, Leonard; Morisset, Sabine; Picaud, Sylvain; Cacciani, Patrice; Grosliere, Marie-Christine; Joly, Gilles; Joly, Nicolas; Kudlinsky, Alexandre; Martinelli, Gilbert; Buchard, Virginie; Tudorie, Marcela; Khelkhal, Mohamed; Cosleou, Jean; Hennequin, Daniel; Beaugeois, Maxime; Lebrun, Nathalie; Droz, Daniel; El Aydam, Mohamed; Gama, Marie-Jose; Ferri, Sandrine; Schyns, Bernadette; Courty, Jean Michel

    2008-07-01

    This colloquium of the French Physics Society on atomic, molecular and optical physics (and more particularly on molecular spectroscopy) comprised several mini-colloquia: methane and its applications in planetology, moving mirrors and Casimir, atoms and molecules in interaction with surfaces, electronic properties of small molecules, molecular spectroscopy for atmospheric applications, quantum memories in atomic sets, methods and applications of reaction dynamics, dynamics of super-excited molecular statuses, mass spectrometry, quantum spectroscopy and chemistry, spectroscopy and reactivity of of confined molecules, electronic and molecular dynamics, dipolar quantum gases. It also comprised plenary sessions: atto-second optics, the atomic Hanbury-Brown-Twiss effect with fermions and bosons, atom and molecule slowing down by Zeeman effect and by Stark effect on Rydberg levels, non destructive counting of photons trapped in a cavity, interstellar chemistry, atom-surface van der Waals interaction noticed in the exotic regime of short distances, communication, vulgarisation and education (the multiple lives of a scientific result), the actual precision of molecular parameters, towards the formation of an amine acid precursor in the interstellar medium via proton transfer, prediction of the ionized and excited molecular electronic structure by Quantum Chemistry (from bi-atomic to bio-molecules), direct observation of Anderson location of matter waves in a controlled disordered potential, experimental observation of the Anderson transition of cold atoms, ultra-cold collisions as a key towards the quantum world, Quantum physics with a single atom, Teramobile or plasma filaments to study the atmosphere, optimal control or how to discriminate two almost identical bio-molecules, infrared spectroscopy as a new dimension for mass spectrometry, chiral recognition in gaseous phase, interactions and reactions between H atoms and graphite surfaces, modelling of gas

  12. Preparation of chitosan oligomers COS and their effect on the retrogradation of intermediate amylose rice starch.

    Science.gov (United States)

    Wu, Yue; Lin, Qin Lu; Chen, Zheng Xing; Wu, Wei; Xiao, Hua Xi

    2012-12-01

    Chitosan oligomers (COS) were obtained by enzymatic hydrolysis and H2O2 oxidative treatment, and then separated into different fractions using ultra-filtration membranes. Each COSM fraction prepared using enzymatic hydrolysis retained its structure, especially the reduced end residue (-NH2 group), and had a peak for molecular weight. On the other hand, each COSH fraction prepared by oxidative treatment had partly damaged -NH2 groups and two peaks for molecular weight. These results indicate that the same COS fractions prepared by the two methods differ in their amino groups and in their molecular weights, though they can both pass through the same size ultra-filtration membrane. The effect of COS on the retrogradation of intermediate amylose rice starch (IA-RS) was also investigated. The 5 k COS determined its anti-retrogradation capability. All COSH fractions from oxidative treatment had no effect on the retrogradation.

  13. Influence of the physico-chemical characteristics of chito-oligosaccharides (COS) on antioxidant activity.

    Science.gov (United States)

    Mengíbar, Marian; Mateos-Aparicio, Inmaculada; Miralles, Beatriz; Heras, Angeles

    2013-09-12

    Chito-oligosaccharides (COS) are being used as important functional materials for many applications due to their bioactivities. The aim of this research has been to assess the relationship between the physico-chemical characteristics, average molecular weight (Mw), acetylation degree (DA), polymerization degree (DP) and specially sequence composition determined by MALDI-TOF MS and the antioxidant properties of COS. These oligosaccharides were obtained by enzymatic depolymerization with chitosanase and lysozyme using a specific chitosan and its reacetylated product. The COS fraction below 5 kDa obtained from chitosanase depolymerization showed the highest capacity to scavenge DPPH radicals and to reduce Fe(3+). A correlation was found between the relative amount of molecules with a given A/D (acetylated vs deacetylated units) ratio within the COS and their antioxidant activity, which could be used to predict the antioxidant behavior of a fraction of chito-oligosaccharides. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Concurrent CO2 and COS fluxes across major biomes in Europe

    Science.gov (United States)

    Spielmann, Felix M.; Kitz, Florian; Hammerle, Albin; Gerdel, Katharina; Ibrom, Andreas; Kolle, Olaf; Migliavacca, Mirco; Moreno, Gerardo; Noe, Steffen M.; Wohlfahrt, Georg

    2017-04-01

    The trace gas carbonyl sulfide (COS) has been proposed as a tracer for canopy gross primary production (GPP), canopy transpiration and stomatal conductance of plant canopies in the last few years. COS enters the plant leaf through the stomata and diffuses through the intercellular space, the cell wall, the plasma membrane and the cytosol like carbon dioxide (CO2). It is then catalyzed by the enzyme carbonic anhydrase in a one-way reaction to hydrogen sulfide and CO2. This one-way flux into the leaf makes COS a promising tracer for the GPP. However, this approach assumes that the ratio of the deposition velocities between COS and CO2 is constant, which must be determined in field experiments covering a wide variety of ecosystems. The overarching objective of this study was to quantify the relationship between the ecosystem-scale exchange of COS and CO2 and thus, to test for the potential of COS to be used as a universal tracer for the plant canopy CO2 exchange. Between spring 2015 and summer 2016 we set up our quantum cascade laser at different field sites across Europe. These sites included a managed temperate mountain grassland (AUT), a savanna (ESP), a temperate beech forest (DEN) and a hemiboreal forest (EST). On each of these sites, we conducted ecosystem scale eddy covariance and soil chamber measurements. Since the soil COS flux contribution, especially in grass dominated ecosystems, could not be neglected, we had to derive the actual canopy COS fluxes for all the measurement sites. Using these fluxes we compared the ecosystem relative uptake (ERU) of the sites and searched for factors affecting its variability. We then used the influential factors to scale the ERU to be comparable under different field sites and conditions. Furthermore we also calculated the GPP using conventional CO2 flux partitioning and compared the results with the approach of using the leaf relative uptake.

  15. Construction of porcine CCK pDNA and its expression in COS-7 cells.

    Science.gov (United States)

    Bai, Jigang; Lü, Yi; Bai, Qiaoling

    2007-06-01

    CCK correlates with the generation and progression of pancreatic cancer. The research aims to construct eukaryotic expression plasmid pIRES2-EGFP/CCK (CCK pDNA) and transiently express it in COS-7 cells. Total RNA was extracted from porcine intestinal mucosa. RT-PCR was used to amplify the aimed segments CCKcDNA which was then digested with EcoR1 and BamH1 and inserted into a eukaryotic expression plasmid pIRES2-EGFP to construct CCK pDNA. The constructed plasmid was transfected into COS-7 cells by lepofectamin 2000-mediated transfer method. The expression of CCK in transfected COS-7 cells was detected 24, 48 and 72 h post-transfection with fluorescence microscopy and the expression level of CCK mRNA in transfected COS-7 cells was assayed by using RT-PCR. The results showed CCK pDNA was successfully constructed and expressed transiently in COS-7 cells. Green fluorescent protein could be detected in the COS-7 cells transfected with porcine CCK pDNA 24 h post-transfection. At 48th h post-transfection, the number of positive cells was increased significantly and much brighter green fluorescence could be detected. And 72 h post-transfection, the green fluorescence of positive cells became even stronger, while no green fluorescence was detected in the control group. The expression of CCK mRNA in the cells was detectable by using RT-PCR. In COS-7 cells transfected with CCK pDNA a high level of porcine CCK mRNA was detected while no expression of porcine CCKmRNA was found in the cells transfected with null plasmid. It was concluded CCK pDNA was expressed successfully in COS-7 cells, which lays a foundation for further research on the relationship between CCK and tumor.

  16. Sin(x)**2 + cos(x)**2 = 1. [programming identities using comparative combinatorial substitutions

    Science.gov (United States)

    Stoutemyer, D. R.

    1977-01-01

    Attempts to achieve tasteful automatic employment of the identities sin sq x + cos sq x = 1 and cos sq h x -sin sq h x = 1 in a manner which truly minimizes the complexity of the resulting expression are described. The disappointments of trigonometric reduction, trigonometric expansion, pattern matching, Poisson series, and Demoivre's theorem are related. The advantages of using the method of comparative combinatorial substitutions are illustrated.

  17. Autism Society

    Science.gov (United States)

    ... Español Improving the lives of all affected by autism. The Autism Society is the nation's leading grassroots ... more Improving the lives of all affected by autism. The Autism Society is the nation's leading grassroots ...

  18. The Politics of Frontier Mining: Local Chieftains, Chinese Miners, and Upland Society in the Nông Văn Vân Uprising in the Sino-Vietnamese Border Area, 1833–1835

    Directory of Open Access Journals (Sweden)

    Vũ Đường Luân

    2014-06-01

    Full Text Available This article, part of a longer study of the history of mining in Vietnam, argues that the Nông Văn Vân uprising (1833–1835 in the northern uplands of Vietnam brings into relief the importance of mining in the Vietnamese economy of the nineteenth century. It also highlights the consequences of Emperor Minh Mệnh’s dual agenda of extracting more tax revenues from mining operations and expanding the reach of the state by replacing hereditary tribal chieftains with imperial bureaucrats. While the uprising was quelled, the imperial agenda could not be fully realized in the face of local opposition and declining revenue from mining. The uprising reflected the multiethnic nature of border society, composed as it was of Vietnamese, local minority populations, and a significant number of Chinese mine owners, workers, and providers of goods and services to the mining towns. In ordinary times, the border was regularly flouted as kinship relations, trading networks, and ethnic affinity transcended allegiance to either the Qing or the Nguyễn in this borderland. Although the uprising was formally contained within the Vietnamese territory, rebels were able to seek refuge and recruit new adherents in China. And while the Nguyễn court was eventually able to subdue the rebels, its centralizing policies and attempts at extracting more revenues from mining were ultimately unsuccessful in the face of reemerging local and transborder forces.

  19. Multi-channel photon migration study in visible Chinese human muscle for optical detection of deep vein thrombosis

    Science.gov (United States)

    Sun, Yunlong; Li, Ting

    2016-03-01

    Deep vein thrombosis (DVT) always induced venous thrombosis. Most cases of venous thrombosis were induced by deep vein thrombosis (DVT), with high incidence rate of >60% in >60 years old people. Near-infrared spectroscopy (NIRS) were reported recently to be an intriguing and potential technique in detecting DVT in clinics. However, the photon transport is still unclear, which is crucial for the image reconstruction of the updated development called as NIRS-based DVT imager. Here we employed the Monte Carlo simulation software for 3D voxelized media (MCVM) and the Visible Chinese Human (VCH) model, which segmentation is finest in the world, to simulate multi-channel photon migration in calf muscle. And the image reconstruction of DVT hemodynamic distribution was achieved. This study, for the first time, provides the most realistic 3-D multichannel photon migration for NIRS study on DVT, and explored the image reconstruction for furtherly developing a NIRS-based DVT imager.

  20. Mass Society

    DEFF Research Database (Denmark)

    Borch, Christian

    2017-01-01

    Mass society is a societal diagnosis that emphasizes – usually in a pejorative, modernity critical manner – a series of traits allegedly associated with modern society, such as the leveling of individuality, moral decay, alienation, and isolation. As such, the notion of mass society generalizes...

  1. Microbial, Physical and Chemical Drivers of COS and 18O-CO2 Exchange in Soils

    Science.gov (United States)

    Meredith, L. K.; Boye, K.; Whelan, M.; Pang, E.; von Sperber, C.; Brueggemann, N.; Berry, J. A.; Welander, P. V.

    2015-12-01

    Carbonyl sulfide (COS) and the oxygen isotope composition (δ18O) of CO2 are potential tools for differentiating the contributions of photosynthesis and respiration to the balance of global carbon cycling. These processes are coupled at the leaf level via the enzyme carbonic anhydrase (CA), which hydrolyzes CO2 in the first biochemical step of the photosynthetic pathway (CO2 + H2O ⇌ HCO3- + H+) and correspondingly structural analogue COS (COS + H2O → CO2 + H2S). CA also accelerates the exchange of oxygen isotopes between CO2 and H2O leading to a distinct isotopic imprint [1]. The biogeochemical cycles of these tracers include significant, yet poorly characterized soil processes that challenge their utility for probing the carbon cycle. In soils, microbial CA also hydrolyze COS and accelerate O isotope exchange between CO2 and soil water. Soils have been observed to emit COS by undetermined processes. To account for these soil processes, measurements are needed to identify the key microbial, chemical, and physical factors. In this study, we survey COS and δ18O exchange in twenty different soils spanning a variety of biomes and soil properties. By comparing COS fluxes and δ18O-CO2 values emitted from moist soils we investigate whether the same types of CA catalyze these two processes. Additionally, we seek to identify the potential chemical drivers of COS emissions by measuring COS fluxes in dry soils. These data are compared with soil physical (bulk density, volumetric water content, texture), chemical (pH, elemental analysis, sulfate, sulfur K-edge XANES), and microbial measurements (biomass and phylogeny). Furthermore, we determine the abundance and diversity of CA-encoding genes to directly link CA with measured soil function. This work will define the best predictors for COS fluxes and δ18O-CO2 values from our suite of biogeochemical measurements. The suitability of identified predictor variables can be tested in follow-up studies and applied for modeling

  2. Planetary Society

    Science.gov (United States)

    Murdin, P.

    2000-11-01

    Carl Sagan, Bruce Murray and Louis Friedman founded the non-profit Planetary Society in 1979 to advance the exploration of the solar system and to continue the search for extraterrestrial life. The Society has its headquarters in Pasadena, California, but is international in scope, with 100 000 members worldwide, making it the largest space interest group in the world. The Society funds a var...

  3. Retinal nerve fiber layer thickness measured by optical coherence tomography in Chinese teenagers aged from 13 years old to 18 years old

    Directory of Open Access Journals (Sweden)

    Yu-Ming Zhang

    2014-04-01

    Full Text Available AIM: To establish a reference range of retinal nerve fiber layer(RNFLthickness by optical coherence tomography(OCTin Chinese teenagers aged from 13 to 18 years old, and investigate its relationship with age, eye side, gender, and ethnic group.METHODS: A total of 402 eyes from 201 normal Chinese aged from 13 to 18 years old were recruited for this study. Optic disk with 3.4mm diameter circle in different global average, quadrant and part-time bit retinal nerve fiber layer thickness(RNFLTwas measured by RNFL thickness average analysis program. Their RNFLT at different part-time bit, quadrant and global average RNFLT around the disc were measured by OCT with 3.4mm diameter circle, using the RNFL thickness average analysis program. The data was analyzed with SPSS statistical 19.0. The influences of several factors(such as age, eye side, gender, and ethnic groupon RNFLT were also analyzed.RESULTS: The global average RNFLT at 13, 14, 15, 16, 17, 18 years old was 108.32±9.42μm, 109.23±9.67μm, 110.36±11.14μm, 111.27±10.21μm, 109.23±9.67μm, 112.11±8.83μm respectively. RNFLT of right eyes was 109.82±8.93μm and of left eyes was 110.33±9.89μm. All of the male's average RNFLT was 110.14±10.02μm, and all of the female's average RNFLT was 109.96±11.22μm. The average RNFLT of Han nationality was 110.22±9.31μm and of non-Han nationality was 109.87±8.65μm. The average RNFLT of all was 110.02±9.87μm, the RNFLT at the superior, nasal, inferior and temporal quadrant was 146.56 ±18.88μm, 76.49±13.28μm, 136.64±16.29μm, 82.01±12.55μm respectively. There was no significant difference in gender, eye side, and ethnic group(all PCONCLUSION: This study has established a normal standard reference of RNFLT and its related indexes by OCT in Chinese teenagers aged 13-18 years old. Gender, age, eye side, and ethnic group have no effect on their RNFLT, which has significant difference with adult's data. And for the diagnosis and follow-up of

  4. Optical dating of eolian deposits since the last interglacial along the northern margin of the Chinese Loess Plateau

    Science.gov (United States)

    Lü, Tongyan; Sun, Jimin; Gong, Zhijun

    2018-04-01

    Understanding the chronology of eolian sand-loess-paleosol sequences along the northern margin of the Chinese Loess Plateau (CLP) is crucial for comprehending climate change and the advance and retreat of the adjacent Mu Us desert. In this study, a sand-loess-soil sequence from the northern margin of the CLP was studied by applying the single aliquot regenerative (SAR) protocol to quartz grains, and the multi-elevated-temperature post-IR IRSL (MET-pIRIR) protocol to K-feldspar grains. For equivalent dose (De) determination, 63-90 μm quartz and K-feldspar grains were used. Our results indicate that the MET-pIRIR ages of K-feldspar grains in this sequence range from 94.4 ± 7.0 ka to 148.3 ± 13.3 ka for the last interglacial paleosol (S1); for the upper part of the section, quartz-based SAR-OSL dating was used, yielding ages spanning from 5.8 ± 0.4 ka to 35.9 ± 4.1 ka. After cross-checking these results with previously-reported isochron OSL and TL ages, the reliability of the MET-pIRIR protocol when applied to the last interglacial paleosol was confirmed. Based on a new OSL chronology of the Shimao profile, the studied eolian deposits can be broadly correlated with the last glacial-interglacial cycle, but their dating also points to sedimentary hiatuses occurring at 94.4 ka, 35.9 ka and 5.8 ka, due most probably to strong wind erosion caused by intensified cold-dry winter monsoonal circulations during the last glacial maxima.

  5. Optical detection of λ-cyhalothrin by core-shell fluorescent molecularly imprinted polymers in Chinese spirits.

    Science.gov (United States)

    Wang, Jixiang; Gao, Lin; Han, Donglai; Pan, Jianming; Qiu, Hao; Li, Hongji; Wei, Xiao; Dai, Jiangdong; Yang, Jinghai; Yao, Hui; Yan, Yongsheng

    2015-03-11

    In this study, fluorescent molecularly imprinted polymers (FMIPs), which were for the selective recognition and fluorescence detection of λ-cyhalothrin (LC), were synthesized via fluorescein 5(6)-isothiocyanate (FITC) and 3-aminopropyltriethoxysilane (APTS)/SiO2 particles. The SiO2@FITC-APTS@MIPs were characterized by Fourier transform infrared (FT-IR), UV-vis spectrophotometer (UV-vis), fluorescence spectrophotometer, thermogravimetric analysis (TGA), confocal laser scanning microscope (CLSM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The as-synthesized SiO2@FITC-APTS@MIPs with an imprinted polymer film (thickness was about 100 nm) was demonstrated to be spherically shaped and had good monodispersity, high fluorescence intensity, and good selective recognition. Using fluorescence quenching as the detection tool, the largest fluorescence quenching efficiency (F0/F - 1) of SiO2@FITC-APTS@MIPs is close to 2.5 when the concentration of the LC is 1.0 μM L(-1). In addition, a linear relationship (F0/F - 1= 0.0162C + 0.0272) could be obtained covering a wide concentration range of 0-60 nM L(-1) with a correlation coefficient of 0.9968 described by the Stern-Volmer equation. Moreover, the limit of detection (LOD) of the SiO2@FITC-APTS@MIPs was 9.17 nM L(-1). The experiment results of practical detection revealed that the SiO2@FITC-APTS@MIPs as an attractive recognition element was satisfactory for the determination of LC in Chinese spirits. Therefore, this study demonstrated the potential of SiO2@FITC-APTS@MIPs for the recognition and detection of LC in food.

  6. COS-B observations of localized sources of gamma-ray emission

    Science.gov (United States)

    1977-01-01

    In October 1975, the high-energy gamma-ray flux from the Vela pulsar measured by COS-B was found to be 1.6 to 2.1 times higher than the flux measured by SAS-2 in 1973. This factor is too large to be accounted for by error in the COS-B calibration or analysis. This is supported by a comparison of the COS-B measurement of the narrow-line component from the galactic center region with the flux derived from the measurements of SAS-2; the COS-B flux comes out about 15 percent lower than the SAS-2 figure. It is interesting to note that a glitch in the pulsar period took place about 1 month prior to the COS-B observation; the previous glitch occurred about 1.5 years before the SAS-2 observation. The increased rotational energy loss after the glitch cannot simply explain the increased gamma-ray luminosity. If the two phenomena are related, the gamma-ray emission, absorption, or beaming process must be extremely sensitive to changes in rotational parameters. The existence is confirmed of a second region of enhanced radiation in the galactic anticenter in addition to that from the Crab pulsar.

  7. Therapeutic Delivery of H2S via COS: Small Molecule and Polymeric Donors with Benign Byproducts.

    Science.gov (United States)

    Powell, Chadwick R; Foster, Jeffrey C; Okyere, Benjamin; Theus, Michelle H; Matson, John B

    2016-10-19

    Carbonyl sulfide (COS) is a gas that may play important roles in mammalian and bacterial biology, but its study is limited by a lack of suitable donor molecules. We report here the use of N-thiocarboxyanhydrides (NTAs) as COS donors that release the gas in a sustained manner under biologically relevant conditions with innocuous peptide byproducts. Carbonic anhydrase converts COS into H 2 S, allowing NTAs to serve as either COS or H 2 S donors, depending on the availability of the enzyme. Analysis of the pseudo-first-order H 2 S release rate under biologically relevant conditions revealed a release half-life of 75 min for the small molecule NTA under investigation. A polynorbornene bearing pendant NTAs made by ring-opening metathesis polymerization was also synthesized to generate a polymeric COS/H 2 S donor. A half-life of 280 min was measured for the polymeric donor. Endothelial cell proliferation studies revealed an enhanced rate of proliferation for cells treated with the NTA over untreated controls.

  8. Symmetrical synergy of hybrid CoS2-WS2 electrocatalysts for hydrogen evolution reaction

    KAUST Repository

    Zhou, Xiaofeng

    2017-06-05

    A highly active and stable hybrid electrocatalyst 3D hierarchical CoS2 nanosheets incorporated with WS2 (CoS2@WS2) has been developed via a one-step sulfurization method for the first time, where the contents of WS2 can be adjusted easily. We first prove the addition of small amounts of WS2 enhances the hydrogen evolution reaction (HER) performance of CoS2, and vise versa. In other words, we validated the symmetric synergy for HER between the Co- and W-based sulfide hybrid catalysts. In addition, we confirmed that the formation of nanointerfaces of Co-S-W between CoS2 and WS2 was responsible for the excellent HER activity (an overpotential of -97.2 mV at -10 mA/cm2, a small Tafel slope of 66.0 mV/dec, and prominent electrochemical stability) of hybrid electrocatalyst CoS2@WS2.

  9. Optic Nerve Pit

    Science.gov (United States)

    ... Conditions Frequently Asked Questions Español Condiciones Chinese Conditions Optic Nerve Pit What is optic nerve pit? An optic nerve pit is a ... may be seen in both eyes. How is optic pit diagnosed? If the pit is not affecting ...

  10. NIR assignment of isopsoralen by 2D-COS technology and model application in Yunkang Oral Liquid

    Directory of Open Access Journals (Sweden)

    Yanling Pei

    2015-11-01

    Full Text Available Near infrared (NIR assignment of Isopsoralen was performed using deuterated chloroform solvent and two-dimensional correlation spectroscopy (2D-COS technology. Yunkang Oral Liquid was applied to study Isopsoralen, the characteristic bands by spectral assignment as well as the bands by interval partial least squares (iPLS and synergy interval partial least squares (siPLS were used to establish partial least squares (PLS model. The coefficient of determination in calibration $(R_{\\rm cal}^{2}$ were 0.9987, 0.9970 and 0.9982. The coefficient of determination in cross validation $(R_{\\rm val}^{2}$ were 0.9985, 0.9921 and 0.9982. The coefficient of determination in prediction $(R_{\\rm pre}^{2}$ were 0.9987, 0.9955 and 0.9988. The root mean square error of calibration (RMSEC were 0.27, 0.40 and 0.31 ppm. The root mean square error of cross validation (RMSECV were 0.30, 0.67 and 0.32 ppm. The root mean square error of prediction (RMSEP were 0.23, 0.43 and 0.22 ppm. The residual predictive deviation (RPD were 31.00, 16.58 and 32.41. It turned out that the characteristic bands by spectral assignment had the same results with the chemometrics methods in PLS model. It provided guidance for NIR spectral assignment of chemical compositions in Chinese Materia Medica (CMM.

  11. The Learning of Chinese Idioms through Multimedia Storytelling Prototype

    Science.gov (United States)

    Li, Ee Hui; Hew, Soon Hin; Choo, Siew Hwa

    2016-01-01

    In recent years, the growth of China has successfully boosted the Chinese language to be studied by people from different language-speaking societies. The Chinese language has become the most preferred second or third language among non-Chinese native novices due to the great development of China and global economic change. The Chinese idiom is…

  12. Graphene-wrapped CoS nanoparticles for high-capacity lithium-ion storage.

    Science.gov (United States)

    Gu, Yan; Xu, Yi; Wang, Yong

    2013-02-01

    Graphene-wrapped CoS nanoparticles are synthesized by a solvothermal approach. The product is significantly different from porous CoS microspheres prepared in the absence of graphene under similar preparation conditions. The CoS microspheres and CoS/graphene composite are fabricated as anode materials for lithium-ion batteries. The CoS/graphene composite is found to be better suitable as an anode in terms of higher capacity and better cycling performances. The nanocomposite exhibits an unprecedented high reversible capacity of 1056 mA h/g among all cobalt sulfide-based anode materials. Good cycling performances are also observed at both small and high current rates.

  13. Using Heterologous COS-7 Cells to Identify Semaphorin-Signaling Components.

    Science.gov (United States)

    Sakurai, Atsuko; Doçi, Colleen L; Gutkind, J Silvio

    2017-01-01

    Semaphorins are a family of membrane-bound and secreted type of proteins which were initially identified as chemorepulsive axon guidance molecules. Plexins and neuropilins are two major receptor families of semaphorins, and their common downstream targets are the actin cytoskeleton and cell-to-extracellular matrix adhesions. Semaphorins promote the collapse of growth cones by inducing rapid changes in the cytoskeleton and disassembly of focal adhesion structures. When transfected with appropriate receptors, non-neuronal COS-7 cells exhibit a similar cell collapse phenotype upon semaphorin stimulation. This heterologous system using COS-7 cells has been developed and widely used to investigate semaphorin-signaling pathways. In this chapter, we describe a COS-7 collapse assay protocol used to identify semaphorin-signaling components and a method to produce recombinant class 3 semaphorin proteins.

  14. Observations of the uptake of carbonyl sulfide (COS by trees under elevated atmospheric carbon dioxide concentrations

    Directory of Open Access Journals (Sweden)

    L. Sandoval-Soto

    2012-08-01

    Full Text Available Global change forces ecosystems to adapt to elevated atmospheric concentrations of carbon dioxide (CO2. We understand that carbonyl sulfide (COS, a trace gas which is involved in building up the stratospheric sulfate aerosol layer, is taken up by vegetation with the same triad of the enzymes which are metabolizing CO2, i.e. ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco, phosphoenolpyruvate carboxylase (PEP-Co and carbonic anhydrase (CA. Therefore, we discuss a physiological/biochemical acclimation of these enzymes affecting the sink strength of vegetation for COS. We investigated the acclimation of two European tree species, Fagus sylvatica and Quercus ilex, grown inside chambers under elevated CO2, and determined the exchange characteristics and the content of CA after a 1–2 yr period of acclimation from 350 ppm to 800 ppm CO2. We demonstrate that a compensation point, by definition, does not exist. Instead, we propose to discuss a point of uptake affinity (PUA. The results indicate that such a PUA, the CA activity and the deposition velocities may change and may cause a decrease of the COS uptake by plant ecosystems, at least as long as the enzyme acclimation to CO2 is not surpassed by an increase of atmospheric COS. As a consequence, the atmospheric COS level may rise causing an increase of the radiative forcing in the troposphere. However, this increase is counterbalanced by the stronger input of this trace gas into the stratosphere causing a stronger energy reflection by the stratospheric sulfur aerosol into space (Brühl et al., 2012. These data are very preliminary but may trigger a discussion on COS uptake acclimation to foster measurements with modern analytical instruments.

  15. Buddhist Activism and Chinese Modernity

    Directory of Open Access Journals (Sweden)

    Hung-yok Ip

    2015-02-01

    Full Text Available The history of modern Chinese Buddhism has begun to attract attention in recent years. Some scholars have done inspiring research as they unravel the integration of Buddhism into the highly secularized process of Chinese modernity by drawing on the repository of knowledge on modern China. While this special issue joins this exciting endeavor, it also uses Buddhism as a window to reflect on scholarship on Chinese modernity. Conceptually, this special issue presses scholars in the field of modern China to rethink the place of tradition in the course of modernity. Thematically we show the expansionist impulse of Chinese Buddhism: In addition to envisioning the geographical expansion of their religion, Chinese Buddhists have endeavored to enhance the significance of Buddhism in various dimensions of Chinese society in particular and human life in general.

  16. Light-Activated COS/H2S Donation from Photocaged Thiocarbamates.

    Science.gov (United States)

    Zhao, Yu; Bolton, Sarah G; Pluth, Michael D

    2017-05-05

    Hydrogen sulfide (H 2 S) is an important biomolecule, and responsive chemical tools for its delivery are needed. Here, we utilize the photocleavable o-nitrobenzyl group to unmask caged thiocarbamates and to access photoactivated H 2 S releasing molecules. These donors function by the initial release of carbonyl sulfide (COS), which is quickly hydrolyzed to H 2 S by carbonic anhydrase (CA). Our investigations demonstrate that o-nitrobenzyl-caged thiocarbamates can serve as a donor platform for the bio-orthogonal stimulated release of COS/H 2 S.

  17. Individualised controlled ovarian stimulation (iCOS: maximising success rates for assisted reproductive technology patients

    Directory of Open Access Journals (Sweden)

    Bosch Ernesto

    2011-06-01

    Full Text Available Abstract Background In the last two decades, pregnancy rates for patients undergoing in-vitro fertilisation (IVF have significantly increased. Some of the major advances responsible for this improvement were the introduction of controlled ovarian stimulation (COS for the induction of multiple follicle development, and the utilisation of mid-luteal gonadotropin-releasing hormone agonists to achieve pituitary down-regulation and full control of the cycle. As a result, a combination of a gonadotropin-releasing hormone agonist with high doses (150-450 IU/day of recombinant follicle-stimulating hormone has become the current standard approach for ovarian stimulation. However, given the heterogeneity of patients embarking on IVF, and the fact that many different drugs can be used alone or in different combinations (generating multiple potential protocols of controlled ovarian stimulation, we consider the need to identify special populations of patients and adapt treatment protocols accordingly, and to implement a more individualised approach to COS. Discussion Studies on mild, minimal and natural IVF cycles have yielded promising results, but have focused on fresh embryo transfers and included relatively young patient populations who generally have the potential for more favourable outcomes. The efficacy of these protocols in patients with a poorer prognosis remains to be tested. When comparing protocols for COS, it is important to think beyond current primary endpoints, and to consider the ideal quality and quantity of oocytes and embryos being produced per stimulated patient, in order to achieve a pregnancy. We should also focus on the cumulative pregnancy rate, which is based on outcomes from fresh and frozen embryos from the same cycle of stimulation. Individualised COS (iCOS determined by the use of biomarkers to test ovarian reserve has the potential to optimise outcomes and reduce safety issues by adapting treatment protocols according to each

  18. Structural Alterations of Segmented Macular Inner Layers in Aquaporin4-Antibody-Positive Optic Neuritis Patients in a Chinese Population.

    Directory of Open Access Journals (Sweden)

    Chunxia Peng

    Full Text Available This study aimed to analyse the structural injury of the peripapillary retinal nerve fibre layer (pRNFL and segmented macular layers in optic neuritis (ON in aquaporin4-antibody (AQP4-Ab seropositivity(AQP4-Ab-positiveON patients and in AQP4-Ab seronegativity (AQP4-Ab-negative ON patients in order to evaluate their correlations with the best-corrected visual acuity (BCVA and the value of the early diagnosis of neuromyelitis optica (NMO.This is a retrospective, cross-sectional and control observational study.In total, 213 ON patients (291 eyes and 50 healthy controls (HC (100 eyes were recruited in this study. According to a serum AQP4-Ab assay, 98 ON patients (132 eyes were grouped as AQP4-Ab-positive ON and 115 ON patients (159 eyes were grouped as AQP4-Ab-negative ON cohorts. All subjects underwent scanning with spectralis optical coherence tomography (OCT and BCVA tests. pRNFL and segmented macular layer measurements were analysed.The pRNFL thickness in AQP4-Ab-positive ON eyes showed a more serious loss during 0-2 months (-27.61μm versus -14.47 μm and ≥6 months (-57.91μm versus -47.19μm when compared with AQP4-Ab-negative ON eyes. AQP4-Ab-positive ON preferentially damaged the nasal lateral pRNFL. The alterations in the macular ganglion cell layer plus the inner plexiform layer (GCIP in AQP4-Ab-positive ON eyes were similar to those in AQP4-Ab-negative ON eyes. AQP4-Ab-positive ON eyes had entirely different injury patterns in the inner nuclear layer (INL compared with AQP4-Ab-negative ON eyes during the first 6 months after the initial ON attack. These differences were as follows: the INL volume of AQP4-Ab-positive ON eyes had a gradual growing trend compared with AQP4-Ab-negative ON eyes, and it increased rapidly during 0-2 months, reached its peak during 2-4 months, and then decreased gradually. The pRNFL and GCIP in AQP4-Ab-positive ON eyes had positive correlations with BCVA. When the pRNFL thickness decreased to 95%CI (50.77

  19. Solubility and Diffusivity Data for the Absorption of COS, CO2, and N2O in Amine Solutions

    NARCIS (Netherlands)

    Littel, Rob J.; Versteeg, Geert F.; Swaaij, Wlm P.M. van

    1992-01-01

    Absorption data for COS and N2O in aqueous solutions of N-methyldiethanolamine (MDEA), ethylene glycol, and sulfolane (tetrahydrothiophene 1,1-dioxide) at 298 K and solubility data for COS in water at temperatures ranging from 298 to 338 K are presented. Also density, viscosity, N2O solubility, and

  20. Catalytic hydrolysis of COS over CeO{sub 2} (110) surface: A density functional theory study

    Energy Technology Data Exchange (ETDEWEB)

    Song, Xin; Ning, Ping [Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Wang, Chi [Faculty of Chemical Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Li, Kai, E-mail: likaikmust@163.com [Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Tang, Lihong; Sun, Xin [Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500 (China)

    2017-08-31

    Graphical abstract: CeO{sub 2} decreases the maximum energy barrier by 76.15 kcal/mol. H{sub 2}O plays a role as a bridge in the process of joint adsorption. Catalytic effect of CeO{sub 2} in the hydrolysis of COS is mainly reflected on the C−O channel. - Highlights: • H{sub 2}O is easier adsorbed on the CeO{sub 2} (110) surface than COS. • When COS and H{sub 2}O jointly adsorb on the CeO{sub 2} (110) surface, the H{sub 2}O molecule plays a role as a bridge. • Ce−O−H bond can enhance the adsorption effect. • Catalytic effect of CeO{sub 2} in the hydrolysis of COS is mainly reflected on the C−O channel. - Abstract: Density functional theory (DFT) calculations were performed to investigate the reaction pathways for catalytic hydrolysis of COS over CeO{sub 2} (110) surface using Dmol{sup 3} model. The thermodynamic stability analysis for the suggested routes of COS hydrolysis to CO{sub 2} and H{sub 2}S was evaluated. The absolute values of adsorption energy of H{sub 2}O-CeO{sub 2} are higher than that of COS-CeO{sub 2}. Meanwhile, the adsorption energy and geometries show that H{sub 2}O is easier adsorbed on the surface of CeO{sub 2} (110) than COS. H{sub 2}O plays a role as a bridge in the process of joint adsorption. H{sub 2}O forms more Ce−O−H groups on the CeO{sub 2} (110) surface. CeO{sub 2} decreases the maximum energy barrier by 76.15 kcal/mol. The migration of H from H{sub 2}O to COS is the key for the hydrolysis reaction. C−O channel is easier to occur than C−S channel. Experimental result shows that adding of CeO{sub 2} can increase COS removal rate and prolong the 100% COS removal rate from 180 min to 210 min. The difference between Fe{sub 2}O{sub 3} and CeO{sub 2} for the hydrolysis of COS is characterized in the atomic charge transfer and the formation of H−O bond and H−S bond. The transfer effect of H in H{sub 2}O to S in COS over CeO{sub 2} decreases the energy barriers of hydrolysis reaction, and enhances the reaction

  1. Transforming Society

    DEFF Research Database (Denmark)

    Enemark, Stig; Dahl Højgaard, Pia

    2017-01-01

    This paper provides an understanding of the cadastral evolution in Denmark with a focus on establishing the cadastre as an outcome of the enclosure movement in the late 1700s. The purpose of the cadastre was collection of tax based on the yielding capacity of the soil. The Danish cadastre, this way......, was a result of transforming society from a feudal system to a capitalistic and market based economy. This story is interesting in itself - but it also provides a key to understanding the cadastral system of today. The system has evolved over time and now serves a whole range of functions in society. The paper...

  2. Applied optics and optical design

    CERN Document Server

    Conrady, Alexander Eugen

    1957-01-01

    ""For the optical engineer it is an indispensable work."" - Journal, Optical Society of America""As a practical guide this book has no rival."" - Transactions, Optical Society""A noteworthy contribution,"" - Nature (London)Part I covers all ordinary ray-tracing methods, together with the complete theory of primary aberrations and as much of higher aberration as is needed for the design of telescopes, low-power microscopes and simple optical systems. Chapters: Fundamental Equations, Spherical Aberration, Physical Aspect of Optical Images, Chromatic Aberration, Design of Achromatic Object-Glass

  3. La recreació fisicoesportiva i el seu tractament del cos: una anàlisi crítica

    Directory of Open Access Journals (Sweden)

    J. Pere Molina Alventosa

    2010-06-01

    Full Text Available En aquest treball es realitza una anàlisi crítica de la recreació fisicoesportiva a partir de la seva concepció i tractament del cos. Per fer-ho, es parteix de la dimensió subjectiva del lleure i del sentit de la recreació fisicoesportiva, igual com del significat atribuït al cos en les societats postmodernes. D’aquesta manera, l’anàlisi distingeix dues concepcions bàsiques del cos, ‘el cos com a producte’ i ‘el cos com a experiència’, que deriven, respectivament, en dues orientacions de la recreació fisicoesportiva: la utilitària i l’emancipadora. En uns comentaris finals, es qüestiona el posicionament de la professió davant de la recreació fisicoesportiva com a mercat emergent.

  4. Practice patterns of Canadian Ophthalmological Society members in cataract surgery--2009 survey.

    Science.gov (United States)

    Ong-Tone, Lindsay; Bell, Ali

    2010-04-01

    To establish the practice patterns of the members of the Canadian Ophthalmological Society (COS) in cataract surgery. A questionnaire consisting of multiple choice questions on cataract surgery practices was sent as an attachment by email to the members of the COS. Seven-hundred and seventy-seven COS members with a valid email address in the Society's database. A 29-item questionnaire pertaining to cataract surgery practices was sent by email. A reminder email with the attached questionnaire was sent 3 weeks later. The survey data were descriptively analyzed with the Statistical Package for the Social Sciences (SPSS) v 16.0 software and the results compared with those from surveys by the American Society of Cataract and Refractive Surgery and the European Society of Cataract and Refractive Surgeons. There were 161 responses. Of these, 30 members did not do any cataract surgery, and a further 8 responses were incomplete, therefore, 123 responses were analyzed. The majority of the respondents (69.1%) were between 40-59 years old. Phacoemulsification was the procedure of choice of all the respondents. Topical anaesthesia with clear corneal incisions was the most popular technique. Only 59.8% of respondents used a NSAID drop while 90.1% used a steroid drop postoperatively. The practice patterns of the members of the COS for cataract surgery have not been reported before. This survey will serve as a baseline for future ones.

  5. One-step hydrothermal synthesis of flower-like CoS ...

    Indian Academy of Sciences (India)

    50

    cycles, there are only 12.7% loss of the original specific capacitance. The results signify that the CoS supercapacitor ... hierarchitectures showed a specific capacitance of 357 F. g-1 at a current density of 0.5. A. g-1. After 2000 galvanostatic .... slightly to more positive and negative directions separately. This occurs because.

  6. In COS cells Vpu can both stabilize tetherin expression and counteract its antiviral activity.

    Science.gov (United States)

    Waheed, Abdul A; Kuruppu, Nishani D; Felton, Kathryn L; D'Souza, Darren; Freed, Eric O

    2014-01-01

    The interferon-inducible cellular protein tetherin (CD317/BST-2) inhibits the release of a broad range of enveloped viruses. The HIV-1 accessory protein Vpu enhances virus particle release by counteracting this host restriction factor. While the antagonism of human tetherin by Vpu has been associated with both proteasomal and lysosomal degradation, the link between Vpu-mediated tetherin degradation and the ability of Vpu to counteract the antiviral activity of tetherin remains poorly understood. Here, we show that human tetherin is expressed at low levels in African green monkey kidney (COS) cells. However, Vpu markedly increases tetherin expression in this cell line, apparently by sequestering it in an internal compartment that bears lysosomal markers. This stabilization of tetherin by Vpu requires the transmembrane sequence of human tetherin. Although Vpu stabilizes human tetherin in COS cells, it still counteracts the ability of tetherin to suppress virus release. The enhancement of virus release by Vpu in COS cells is associated with a modest reduction in cell-surface tetherin expression, even though the overall expression of tetherin is higher in the presence of Vpu. This study demonstrates that COS cells provide a model system in which Vpu-mediated enhancement of HIV-1 release is uncoupled from Vpu-mediated tetherin degradation.

  7. Inhibition of Mitochondrial Bioenergetics by Esterase-Triggered COS/H2S Donors.

    Science.gov (United States)

    Steiger, Andrea K; Marcatti, Michela; Szabo, Csaba; Szczesny, Bartosz; Pluth, Michael D

    2017-08-18

    Hydrogen sulfide (H 2 S) is an important biological mediator, and synthetic H 2 S donating molecules provide an important class of investigative tools for H 2 S research. Here, we report esterase-activated H 2 S donors that function by first releasing carbonyl sulfide (COS), which is rapidly converted to H 2 S by the ubiquitous enzyme carbonic anhydrase (CA). We report the synthesis, self-immolative decomposition, and H 2 S release profiles of the developed scaffolds. In addition, the developed esterase-triggered COS/H 2 S donors exhibit higher levels of cytotoxicity than equivalent levels of Na 2 S or the common H 2 S donors GYY4137 and AP39. Using cellular bioenergetics measurements, we establish that the developed donors reduce cellular respiration and ATP synthesis in BEAS 2B human lung epithelial cells, which is consistent with COS/H 2 S inhibition of cytochrome c oxidase in the mitochondrial respiratory chain although not observed with common H 2 S donors at the same concentrations. Taken together, these results may suggest that COS functions differently than H 2 S in certain biological contexts or that the developed donors are more efficient at delivering H 2 S than other common H 2 S-releasing motifs.

  8. COS-B observations of the high energy gamma radiation from the galactic disc

    Science.gov (United States)

    Paul, J.

    1976-01-01

    During the first months of operation, COS-B has observed galactic high energy gamma rays from the galactic disc. In the galactic center and Vela regions the disc emission distribution was measured. From these data the existence of a local ( 1 kpc) and a distant ( 3 kpc) emitting region is apparent in the general direction of the inner galaxy.

  9. Kinetics of COS with primary and secondary amines in aqueous solutions

    NARCIS (Netherlands)

    Littel, R.J.; Littel, R.J.; Versteeg, Geert; van Swaaij, Willibrordus Petrus Maria

    1992-01-01

    The reaction between COS and aqueous solutions of primary and secondary amines has been studied by means of the stirred cell technique. Kinetic experiments at temperatures 283 to 333 K were carried out with MEA, DGA, DEA, DIPA, MMEA, AMP, and MOR. All kinetic experiments could be described by a

  10. Plant immunity induced by COS-OGA elicitor is a cumulative process that involves salicylic acid.

    Science.gov (United States)

    van Aubel, Géraldine; Cambier, Pierre; Dieu, Marc; Van Cutsem, Pierre

    2016-06-01

    Plant innate immunity offers considerable opportunities for plant protection but beside flagellin and chitin, not many molecules and their receptors have been extensively characterized and very few have successfully reached the field. COS-OGA, an elicitor that combines cationic chitosan oligomers (COS) with anionic pectin oligomers (OGA), efficiently protected tomato (Solanum lycopersicum) grown in greenhouse against powdery mildew (Leveillula taurica). Leaf proteomic analysis of plants sprayed with COS-OGA showed accumulation of Pathogenesis-Related proteins (PR), especially subtilisin-like proteases. qRT-PCR confirmed upregulation of PR-proteins and salicylic acid (SA)-related genes while expression of jasmonic acid/ethylene-associated genes was not modified. SA concentration and class III peroxidase activity were increased in leaves and appeared to be a cumulative process dependent on the number of sprayings with the elicitor. These results suggest a systemic acquired resistance (SAR) mechanism of action of the COS-OGA elicitor and highlight the importance of repeated applications to ensure efficient protection against disease. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. COS-B observations of localised sources of gamma-ray emission

    Science.gov (United States)

    Mayer-Hasselwander, H.

    1976-01-01

    In October 1975 the high energy gamma ray flux from the Vela pulsar was measured by COS-B to be 1.6 to 2.1 times higher than the flux measured by SAS-2 in 1973. The existence is confirmed of a second region of enhanced radiation in the galactic anticenter in addition to that from the Crab pulsar.

  12. One-step hydrothermal synthesis of flower-like CoS ...

    Indian Academy of Sciences (India)

    2018-03-29

    Mar 29, 2018 ... Abstract. Flower-like CoS hierarchitectures were successfully synthesized through a hydrothermal route in the presence of ethylenediamine as ligand and structure-directing agent. The structure and morphology of the products were characterized by X-ray diffraction, transmission electron microscopy, field ...

  13. The influence of vapor pressure deficit (VPD) on the use of carbonyl sulfide (COS) as a photosynthetic tracer

    Science.gov (United States)

    Sun, W.; Maseyk, K. S.; Lett, C.; Seibt, U.

    2017-12-01

    Using carbonyl sulfide (COS) as a tracer to derive gross primary productivity (GPP) estimates requires knowledge of the relationship between leaf COS and CO2 uptake, which is typically embodied in a parameter called leaf relative uptake (LRU) ratio, defined as the concentration normalized COS:CO2 flux ratio. Previous laboratory and field studies have found light as the key environmental driver of LRU due to differential light responses of COS and CO2 uptake imposed by stomatal regulation. But the influences on LRU from other environmental drivers, particularly vapor pressure deficit (VPD) that affects stomatal conductance, remain elusive. Here we show that VPD is an important determinant of the COS-CO2 uptake relationship in a water-stressed ecosystem. We measured leaf COS and CO2 fluxes from a coast live oak with automated leaf chambers in spring 2013 in a southern Californian woodland. In this semiarid ecosystem, both leaf COS and CO2 uptake responded to VPD and showed a midday depression caused by reduced stomatal conductance. Above a moderate light level ( 500 µmol m-2 s-1), COS uptake decreased with light, whereas CO2 uptake saturated. As a result of the VPD-limited COS uptake, LRU value became smaller than 1.0 at high light (> 1000 µmol m-2 s-1), strongly deviating from previous laboratory values that converge to 1.6. Hence, failure to consider VPD influence may result in overestimated LRU value and underestimated CO2 uptake in this ecosystem. Using a coupled photosynthesis-stomatal conductance model, we show that the VPD control on LRU is in accordance with the response of stomatal conductance to VPD. Our results highlight that incorporating the VPD effect into the prediction of LRU value is crucial to the implementation of COS-based photosynthesis estimates in semiarid ecosystems.

  14. Effects of partial La filling and Sb vacancy defects on CoS b3 skutterudites

    Science.gov (United States)

    Hu, Chongze; Zeng, Xiaoyu; Liu, Yufei; Zhou, Menghan; Zhao, Huijuan; Tritt, Terry M.; He, Jian; Jakowski, Jacek; Kent, Paul R. C.; Huang, Jingsong; Sumpter, Bobby G.

    2017-04-01

    Over the past decade, the open frame ("cagey") structure of CoS b3 skutterudite has invited intensive filling studies with various rare-earth elements for delivering state-of-the-art midtemperature thermoelectric performance. To rationalize previously reported experimental results and provide new insight into the underexplored roles of La fillers and Sb vacancies, ab initio density functional theory studies, along with semiclassical Boltzmann transport theory calculations, are performed for pristine CoS b3 of different lattice settings and La-filled CoS b3 with and without Sb's mono- and divacancy defects. The effects of spin-orbit coupling (SOC), partial La filling, Sb vacancy defects, and spin polarization on the electronic and thermoelectric properties are systematically examined. The SOC shows minor effects on the electronic and thermoelectric properties of CoS b3 . The peculiar quasi-Dirac band in the pristine CoS b3 largely survives La filling but not Sb vacancies, which instead introduce dispersive bands in the band gap region. The non-spin-polarized and spin-polarized solutions of La-filled CoS b3 are nearly degenerate. Importantly, the band structure, density of states, and Fermi surface of the latter are significantly spin polarized, giving rise to spin-dependent thermoelectric properties. Seebeck coefficients directly calculated as a function of chemical potential are interpreted in connection with the electronic structures. Temperature-dependent Seebeck coefficients derived for the experimentally studied materials agree well with available experimental data. Seebeck coefficients obtained as a function of charge carrier concentration corroborate the thermoelectrically favorable role at high filling fractions played by the Fermi electron pockets associated with the degenerate valleys in the conduction bands, and also point toward a similar role of the Fermi hole pockets associated with the degenerate hills in the valence bands. These results serve to

  15. Conceptual framework of Tenaga Nasional Berhad (TNB) cost of service (COS) model

    Science.gov (United States)

    Zainudin, WNRA; Ishak, WWM; Sulaiman, NA

    2017-09-01

    One of Malaysia Electricity Supply Industry (MESI) objectives is to ensure Tenaga Nasional Berhad (TNB) economic viability based on a fair economic electricity pricing. In meeting such objective, a framework that investigates the effect of cost of service (COS) on revenue is in great need. This paper attempts to present a conceptual framework that illustrate the distribution of the COS among TNB’s various cost centres which are subsequently redistributed in varying quantities among all of its customer categories. A deep understanding on the concepts will ensure optimal allocation of COS elements between different sub activities of energy production processes can be achieved. However, this optimal allocation needs to be achieved with respect to the imposed TNB revenue constraint. Therefore, the methodology used for this conceptual approach is being modelled into four steps. Firstly, TNB revenue requirement is being examined to ensure the conceptual framework addressed the requirement properly. Secondly, the revenue requirement is unbundled between three major cost centres or business units consist of generation, transmission and distribution and the cost is classified based on demand, energy and customers related charges. Finally, the classified costs are being allocated to different customer categories i.e. Household, Commercial, and Industrial. In summary, this paper proposed a conceptual framework on the cost of specific services that TNB currently charging its customers and served as potential input into the process of developing revised electricity tariff rates. On that purpose, the finding of this COS study finds cost to serve customer varies with the voltage level that customer connected to, the timing and the magnitude of customer demand on the system. This COS conceptual framework could potentially be integrated into a particular tariff structure and serve as a useful tool for TNB.

  16. Remifentanil induces autophagy and prevents hydrogen peroxide-induced apoptosis in Cos-7 cells.

    Science.gov (United States)

    Yoon, Ji-Young; Baek, Chul-Woo; Woo, Mi-Na; Kim, Eun-Jung; Yoon, Ji-Uk; Park, Chang-Hoon

    2016-09-01

    This study investigated the effect of remifentanil pretreatment on Cos-7 cells exposed to oxidative stress, and the influence of remifentanil on intracellular autophagy and apoptotic cell death. Cells were divided into 4 groups: (1) Control: non-pretreated cells were incubated in normoxia (5% CO 2 , 21% O 2 , and 74% N 2 ). (2) H 2 O 2 : non-pretreated cells were exposed to H 2 O 2 for 24 h. (3) RPC+H 2 O 2 : cells pretreated with remifentanil were exposed to H 2 O 2 for 24 h. (4) 3-MA+RPC+H 2 O 2 : cells pretreated with 3-Methyladenine (3-MA) and remifentanil were exposed to H 2 O 2 for 24 h. We determined the cell viability of each group using an MTT assay. Hoechst staining and FACS analysis of Cos-7 cells were performed to observe the effect of remifentanil on apoptosis. Autophagy activation was determined by fluorescence microscopy, MDC staining, and AO staining. The expression of autophagy-related proteins was observed using western blotting. Remifentanil pretreatment increased the viability of Cos-7 cells exposed to oxidative stress. Hoechst staining and FACS analysis revealed that oxidative stress-dependent apoptosis was suppressed by the pretreatment. Additionally, fluorescence microscopy showed that remifentanil pretreatment led to autophagy-induction in Cos-7 cells, and the expression of autophagy-related proteins was increased in the RPC+H 2 O 2 group. The study showed that remifentanil pretreatment stimulated autophagy and increased viability in an oxidative stress model of Cos-7 cells. Therefore, we suggest that apoptosis was activated upon oxidative stress, and remifentanil preconditioning increased the survival rate of the cells by activating autophagy.

  17. INHALATIONAL EXPOSURE TO CARBONYL SULFIDE (COS) PRODUCES BRAIN LESIONS AND ALTERED BRAINSTEM AUDITORY (BAER) AND SOMATOSENSORY (SEP) EVOKED POTENTIALS IN FISHCER 344N RATS.

    Science.gov (United States)

    Because of the amount of carbonyl sulfide (COS) emissions and the lack of toxicological data, COS was listed in the Clean Air Act of 1990 as a Hazardous Air Pollutant. In 1999 COS was nominated by the US EPA to the National Toxicology Program for additional toxicological investig...

  18. Comparison of spectral-domain optical coherence tomography for intra-retinal layers thickness measurements between healthy and diabetic eyes among Chinese adults.

    Directory of Open Access Journals (Sweden)

    Shu-Ting Li

    Full Text Available To compare intra-retinal layer thickness measurements between eyes with no or mild diabetic retinopathy (DR and age-matched controls using Spectralis spectral-domain optical coherence tomography (SD-OCT.Cross-sectional observational analysis study. High-resolution macular volume scans (30° * 25° were obtained for 133 type 2 diabetes mellitus (T2DM patients with no DR, 42 T2DM patients with mild DR and 115 healthy controls. The mean thickness was measured in all 9 Early Treatment Diabetic Retinopathy Study (ETDRS sectors for 8 separate layers, inner retinal layer (IRL, outer retinal layer (ORL and total retina (TR, after automated segmentation. The ETDRS grid consisted of three concentric circles of 1-, 3-, and 6-mm diameter. The superior, inferior, temporal, and nasal sectors of the 3- and 6-mm circles were respectively designated as S3, I3, T3, and N3 and S6, I6, T6, and N6. Linear regression analyses were conducted to evaluate the associations between the intra-retinal layer thicknesses, age, diabetes duration, fasting blood glucose and HbA1c.The mean age and duration of T2DM were 61.1 and 13.7 years, respectively. Although no significant differences in the average TR and ORL volumes were observed among the groups, significant differences were found in the volume and sectorial thicknesses of the inner plexiform layer (IPL, outer plexiform layer (OPL and IRL among the groups. In particular, the thicknesses of the IPL (S3, T3, S6, I6 and T6 sectors and the IRL (S6 sector were decreased in the no-DR group compared with the controls (P < 0.05. The thickness of the OPL (S3, N3, S6 and N6 sectors was thinner in the no-DR group than in mild DR (P < 0.05. The average IPL thickness was significantly negatively correlated with age and the duration of diabetes.The assessment of the intra-retinal layer thickness showed a significant decrease in the IPL and IRL thicknesses in Chinese adults with T2DM, even in the absence of visible microvascular signs of

  19. Measurements of atmospheric carbonyl sulfide during the NASA Chemical Instrumentation Test and Evaluation Project: Implications for the global COS budget

    Science.gov (United States)

    Johnson, James E.; Bandy, Alan R.; Thornton, Donald C.; Bates, Timothy S.

    1993-01-01

    Atmospheric carbonyl sulfide COS concentrations were measured by three analytical systems during the Chemical Instrumentation Test and Evaluation (CITE 3) project. The three systems all used cryogenic sample preconcentration and gas chromatographic (GC) separation but differed in the method of detection. The FPD system used a flame photometric detector, the MS system used a mass selective detector, and the ECD-S system used a fluorinating catalyst followed by an electron capture detector. With the FPD system, we found a mean COS concentration of 510 ppt over the North Atlantic and 442 ppt over the Tropical Atlantic. With the ECD-S system, we found a mean COS concentration of 489 ppt over the North Atlantic and 419 ppt over the Tropical Atlantic. All three systems registered a latitudinal gradient in atmospheric COS of between 1.6 and 2.0 ppt per degree of latitude, with increasing COS concentrations northward which was similar to the gradient measured by Bingemer et al. (1990). It is difficult to reconcile the measured latitudinal concentration gradient with present theories of the global COS budget since the largest sink of COS is thought to be a flux to land plants, most of which are in the northern hemisphere.

  20. Measurements of atmospheric carbonyl sulfide during the NASA Chemical Instrumentation Test and Evaluation Project: Implications for the global COS budget

    Science.gov (United States)

    Johnson, James E.; Bandy, Alan R.; Thornton, Donald C.; Bates, Timothy S.

    1993-12-01

    Atmospheric COS concentrations were measured by three analytical systems during the Chemical Instrumentation Test and Evaluation (CITE 3) project. The three systems all used cryogenic sample preconcentration and gas chromatographic (GC) separation but differed in the method of detection. The FPD system used a flame photometric detector, the MS system used a mass selective detector, and the ECD-S system used a fluorinating catalyst followed by an electron capture detector. With the FPD system, we found a mean COS concentration of 510 ppt over the North Atlantic and 442 ppt over the Tropical Atlantic. With the ECD-S system, we found a mean COS concentration of 489 ppt over the North Atlantic and 419 ppt over the Tropical Atlantic. All three systems registered a latitudinal gradient in atmospheric COS of between 1.6 and 2.0 ppt per degree of latitude, with increasing COS concentrations northward which was similar to the gradient measured by Bingemer et al. (1990). It is difficult to reconcile the measured latitudinal concentration gradient with present theories of the global COS budget since the largest sink of COS is thought to be a flux to land plants, most of which are in the northern hemisphere.

  1. HST/COS Observations of the Quasar HE 2347-4342: Probing the Epoch of He II Patchy Reionization at Redshifts z = 2.4-2.9

    Science.gov (United States)

    Shull, J. Michael; France, Kevin; Danforth, Charles W.; Smith, Britton; Tumlinson, Jason

    2010-10-01

    We report ultraviolet spectra of the high-redshift (z em ≈ 2.9) quasar, HE 2347 - 4342, taken by the Cosmic Origins Spectrograph (COS) on the Hubble Space Telescope. Spectra in the G130M (medium resolution, 1135-1440 Å) and G140L (low resolution, 1030-2000 Å) gratings exhibit patchy Gunn-Peterson absorption in the 303.78 Å Lyα line of He II between z = 2.39-2.87 (G140L) and z = 2.74-2.90 (G130M). With COS, we obtain better spectral resolution, higher signal-to-noise ratio (S/N), and better determined backgrounds than previous studies, with sensitivity to abundance fractions x He II ≈ 0.01 in filaments of the cosmic web. The He II optical depths from COS are higher than those with the Far Ultraviolet Spectroscopic Explorer and range from τHe II = 5, with a slow recovery in mean optical depth to langτHe II rang numerous flux-transmission windows between 1135 and 1186 Å. The He II absorption extends to 1186.26 Å (z = 2.905), including associated absorbers with z abs ≈ z QSO and minimal "proximity effect" of flux transmission at the He II edge. We propose a QSO systemic redshift z QSO = 2.904 ± 0.002, some Δz = 0.019 higher than that derived from O I λ1302 emission. Three long troughs (4-10 Å or 25-60 Mpc comoving distance) of strong He II absorption between z = 2.75and2.90 are uncharacteristic of the intergalactic medium if He II reionized at zr ≈ 3. Contrary to recent indirect estimates (zr = 3.2 ± 0.2) from H I optical depths, the epoch of He II reionization may extend to z <~ 2.7. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained from the data archive at the Space Telescope Science Institute. STScI is operated by the Association of Universities for Research in Astronomy, Inc. under NASA contract NAS5-26555.

  2. Effects of chitosan oligosaccharide (COS) on the glycerol-induced acute renal failure in vitro and in vivo.

    Science.gov (United States)

    Yoon, Hyun Joong; Moon, Myoung E; Park, Haeng Soon; Kim, Hyun Woo; Im, Shun Young; Lee, Jun Haeng; Kim, Young Ho

    2008-02-01

    The purpose of this study was to investigate the effects of chitosanoligosaccharide (COS) on the change of inflammatory response, renal function factor, and renal oxidative stress in glycerol-induced ARF in vitro and in vivo. The molecular weight of COS was approximately below 10 kDa with 90% degree of deacetylation. Renal proximal tubular cells were treated with only COS (0, 0.01, 0.025, 0.05, 0.075 and 0.1%) or COS in the presence of glycerol (4mM). And rats were administered with glycerol (50%, 8 ml/kg) by intramuscular injection for the induction of ARF. For identification the protection effect of COS in the glycerol-induced ARF, rats were administered by COS (0.05 and 0.1%) using P.O. injection. The enzymatic activity of the released RDPase was assayed by the fluorometric method. The level of TNF-alpha in kidney or the culture medium was quantified using ELISA kit (R&D Systems, Minneapolis, USA) and, nitrite concentration was determined by the Griess reaction. We showed that COS stimulated the production of TNF-alpha, NO and the released RDPase. Glycerol increased the concentration of RDPase in kidney and decreased the released RDPase in proximal tubular cells. And, glycerol increased the production of NO, TNF-alpha, creatinine, and MDA, and decreased SOD. However, COS recovered the glycerol-induced inflammatory response, renal function factor, and antioxidant effect in kidney. COS had the antioxidant activity and the anti-inflammatory effect. And maybe that characteristics could help recover the glycerol-induced ARF.

  3. Cryptozoology Society

    Science.gov (United States)

    Richman, Barbara T.

    Reports of Loch Ness monsters, Bigfoot, and the Yeti spring u p from time to time, sparking scientific controversy about the veracity of these observations. Now an organization has been established to help cull, analyze, and disseminate information on the alleged creatures. The International Society of Cryptozoology, formed at a January meeting at the U.S. National Museum of Natural History of the Smithsonian Institution, will serve as the focal point for the investigation, analysis, publication, and discussion of animals of unexpected form or size or of unexpected occurrences in time or space.

  4. Network Society

    DEFF Research Database (Denmark)

    Clausen, Lars; Tække, Jesper

    2017-01-01

    the five strands of theory on the network society. Each theoretical position has its specific implications for acting toward strategic goals. In its entirety, the five perspectives give a thorough understanding of the conditions for successful strategic communication in the 21st century.......Strategic communication needs a thorough understanding of the social forms of interaction, organization and social structure, it works within and through. Success is a scarce resource, and organizations compete to fulfill their mission and advance toward specific goals. In this chapter, we present...

  5. Network Society

    DEFF Research Database (Denmark)

    Clausen, Lars; Tække, Jesper

    2017-01-01

    Strategic communication needs a thorough understanding of the social forms of interaction, organization and social structure, it works within and through. Success is a scarce resource, and organizations compete to fulfill their mission and advance toward specific goals. In this chapter, we present...... the five strands of theory on the network society. Each theoretical position has its specific implications for acting toward strategic goals. In its entirety, the five perspectives give a thorough understanding of the conditions for successful strategic communication in the 21st century....

  6. Network Society

    DEFF Research Database (Denmark)

    Clausen, Lars; Tække, Jesper

    2018-01-01

    Strategic communication needs a thorough understanding of the social forms of interaction, organization and social structure, it works within and through. Success is a scarce resource, and organizations compete to fulfill their mission and advance toward specific goals. In this chapter, we present...... the five strands of theory on the network society. Each theoretical position has its specific implications for acting toward strategic goals. In its entirety, the five perspectives give a thorough understanding of the conditions for successful strategic communication in the 21st century....

  7. Optical instrumentation engineering in science, technology and society; Proceedings of the Sixteenth Annual Technical Meeting, San Mateo, Calif., October 16-18, 1972

    Science.gov (United States)

    Katz, Y. H.

    1973-01-01

    Visual tracking performance in instrumentation is discussed together with photographic pyrometry in an aeroballistic range, optical characteristics of spherical vapor bubbles in liquids, and the automatic detection and control of surface roughness by coherent diffraction patterns. Other subjects explored are related to instruments, sensors, systems, holography, and pattern recognition. Questions of data handling are also investigated, taking into account minicomputer image storage for holographic interferometry analysis, the design of a video amplifier for a 90 MHz bandwidth, and autostereoscopic screens. Individual items are announced in this issue.

  8. Ecological civilization and Chinese philosophy

    Directory of Open Access Journals (Sweden)

    Balchindorjieva O.B.

    2016-10-01

    Full Text Available the author raises the problem of the construction of ecological civilization in China in terms of the definition of «ecological civilization» in the context of traditional Chinese culture in its relationship with the traditional and the modern understanding of harmony and harmonious society, and the development of regulation in the sphere of environmental protection. In the article the analysis of philosophical aspects of this problem is given. The author demonstrates the approach developed by the Chinese scholars to understanding of the ecological civilization as a new stage in the human society’s development coming after industrial society. In conclusion the author proposes to consider this approach a necessary civilizational choice that is to be made by the Chinese society.

  9. Harmonious Society and Ecological Civilization: The concepts’ relationship

    Directory of Open Access Journals (Sweden)

    Balchindorzhieva O.B.

    2016-01-01

    Full Text Available The paper discusses a conceptual basis of a new course of development of the Chinese society that is aimed at sustainable development, solving the environmental pollution issues, achieving harmony in the society. The Chinese authorities proposed a new course of ‘ecological civilization’ development. The authors analyze the issues that arise from the development of ecological civilization in China from the perspective of definition of the term ‘ecological civilization’ in the context of traditional Chinese culture, its relationship with traditional and modern understanding of the harmony and harmonious society, and development of legal regulations in the sphere of environmental protection. We provide the analysis of philosophical aspects of the emergence of ecological society, such as expansion of the Western anthropocentrism in the modern Chinese society, possibility of revival of ecological consciousness that is based on traditional Chinese culture, etc. The paper demonstrates the approach that was developed in the works of Chinese scholars regarding understanding of ecological civilization as a new stage of human society’s development that comes after industrial society. In conclusion, the authors propose to consider that approach as a necessary civilizational choice that is to be taken by the Chinese society.

  10. Hollow Nanotubes of N-Doped Carbon on CoS.

    Science.gov (United States)

    Chen, Yuming; Li, Xiaoyan; Park, Kyusung; Zhou, Limin; Huang, Haitao; Mai, Yiu-Wing; Goodenough, John B

    2016-12-19

    Low-cost, single-step synthesis of hollow nanotubes of N-doped carbon deposited on CoS is enabled by the simultaneous use of three functionalities of polyacrylonitrite (PAN) nanofibers: 1) a substrate for loading active materials, 2) a sacrificial template for creating hollow tubular structures, and 3) a precursor for in situ nitrogen doping. The N-doped carbon in hollow tubes of CoS provides a high-capacity anode of long cycle life for a rechargeable Li-ion or Na-ion battery cell that undergoes the conversion reaction 2 A + +2 e - +CoS →Co+A 2 S with A=Li or Na. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Cos i subjecte pedagògic, de malestars, simulacions i reptes

    OpenAIRE

    A. Cullen, Carlos

    1997-01-01

    Voldria compartir amb vostès en aquesta jornada una breu reflexió sobre el lloc del cos en l'educació, avui i aquí. Parlar de l'educació avui i aquí és parlar d'una crisi, d'incertesa, d'una inquietud, que es tradueix sens dubte en el treball quotidià quan es posa el cos, cada dia, travessats per tots els dubtes i dificultats sobre el sentit i el sense sentit del que es fa o es deixa de fer i que es tradueix també quan és necessari ajuntar els cossos i dejunar en una carpa, o sortir al carrer...

  12. Neutron stress measurement using image plate and the cos α method

    International Nuclear Information System (INIS)

    Sasaki, Toshihiko; Hirose, Yukio; Minakawa, Nobuaki; Morii, Yukio

    2004-01-01

    A new type of the neutron stress measurement method, in which the stress is determined by the cos α method, was studied. A neutron image plate was used in this study for detecting the diffraction image. Steel specimens of 5 mm thickness were used for the tensile stress test. The stresses obtain from the experiment showed one-to-one ratio with respect to the applied stresses, though the misfit stress of about 400 MPa was also observed in the result. A simple correction technique for calibrating raw data was proposed to obtain the true stress. A simulation study was carried out to check the experimental result on the peak positions in the diffraction ring and the stress calculation by the cos α method. (author)

  13. High-Field Nb3Sn Cos-theta Dipole with Stress Management

    Energy Technology Data Exchange (ETDEWEB)

    Novitski, Igor [Fermilab; Carmichael, Justin [Fermilab; Kashikhin, Vadim V. [Fermilab; Zlobin, Alexander V. [Fermilab

    2017-01-01

    Cost-effective superconducting dipole magnets with operating fields up to 16 T are being considered for the LHC en-ergy upgrade (HE-LHC) and a Future Circular Collider (FCC). To demonstrate feasibility of 15 T accelerator quality dipole mag-nets, FNAL as a part of the US-MDP is developing a single-aper-ture Nb3Sn dipole demonstrator based on a 4-layer graded cos-theta coil with 60 mm aperture and cold iron yoke. In parallel, to explore the limit of the Nb3Sn accelerator magnet technology, op-timize magnet design and performance parameters, and reduce magnet cost, magnet design studies are also being performed to push the nominal bore field to 16 T in a 60-mm aperture cos-theta dipole. Results of these studies are reported and discussed in this paper.

  14. Postflight analysis for Delta Program Mission no. 113: COS-B Mission

    Science.gov (United States)

    1976-01-01

    On 8 August 1975, the COS-B spacecraft was launched successfully from the Western Test Range (Delta Program Mission No. 113). The launch vehicle was a three stage Extended Long Tank Delta DSV-3P-11B vehicle. Postflight analyses performed in connection with flight are presented. Vehicle trajectory, stage performance, vehicle reliability and the propulsion, guidance, flight control, electronics, mechanical and structural systems are evaluated.

  15. Linking the potato genome to the conserved ortholog set (COS) markers.

    Science.gov (United States)

    Lindqvist-Kreuze, Hannele; Cho, Kwangsoo; Portal, Leticia; Rodríguez, Flor; Simon, Reinhard; Mueller, Lukas A; Spooner, David M; Bonierbale, Merideth

    2013-06-08

    Conserved ortholog set (COS) markers are an important functional genomics resource that has greatly improved orthology detection in Asterid species. A comprehensive list of these markers is available at Sol Genomics Network (http://solgenomics.net/) and many of these have been placed on the genetic maps of a number of solanaceous species. We amplified over 300 COS markers from eight potato accessions involving two diploid landraces of Solanum tuberosum Andigenum group (formerly classified as S. goniocalyx, S. phureja), and a dihaploid clone derived from a modern tetraploid cultivar of S. tuberosum and the wild species S. berthaultii, S. chomatophilum, and S. paucissectum. By BLASTn (Basic Local Alignment Search Tool of the NCBI, National Center for Biotechnology Information) algorithm we mapped the DNA sequences of these markers into the potato genome sequence. Additionally, we mapped a subset of these markers genetically in potato and present a comparison between the physical and genetic locations of these markers in potato and in comparison with the genetic location in tomato. We found that most of the COS markers are single-copy in the reference genome of potato and that the genetic location in tomato and physical location in potato sequence are mostly in agreement. However, we did find some COS markers that are present in multiple copies and those that map in unexpected locations. Sequence comparisons between species show that some of these markers may be paralogs. The sequence-based physical map becomes helpful in identification of markers for traits of interest thereby reducing the number of markers to be tested for applications like marker assisted selection, diversity, and phylogenetic studies.

  16. Amplification of rabbit hepatocyte growth factor and detection of its expression in COS-7 cell line.

    Science.gov (United States)

    Yao, H; Han, J; Wang, J; Wang, L; Gong, C; Li, L; Liang, Z; Tian, Y

    2015-11-25

    We used RT-PCR, nested PCR to acquire the partial 5'- race fragment of rabbit HGF cDNA and the partial 3'- race fragment of rabbit HGF cDNA. Then, we used recombination PCR to acquire rabbit HGF successfully. Homology analysis was conducted among the sequence of RABHGF and known human and rat HGF by DNAStar. It was proved that high level of homology existed among the sequences of those three HGF genes. We used the acquired gene of RABHGF to construct its recombinant eukaryotic expression vector pcDNA3.1(+)-RABHGF (pRABHGF). The identification of the eukaryotic expression vector pRABHGF by PCR, restriction enzyme and sequencing analysis showed that rabbit HGF gene was correctly inserted into the vector. pRABHGF and pcDNA3.1(+) as controls were transfected into COS-7 cells by lipofectamine. It takes 24h-36h after transfection to detect the expression of RABHGF protein by indirect immunofluorescence assay (IFA). The proliferation of cos-7 cells were evaluated by MTT assay. The result displayed positive effect of RABHGF protein on the proliferation of COS-7 cells. This study lays the foundation for a new gene therapy method for ischemic heart disease.

  17. Buffalo Leukemia Inhibitory Factor Induces Differentiation and Dome-Like Secondary Structures in COS-1 Cells.

    Science.gov (United States)

    Kaur, Gurjeet; Ali, Syed Azmal; Pachauri, Shikha; Malakar, Dhruba; Kaushik, Jai K; Mohanty, Ashok K; Kumar, Sudarshan

    2017-01-01

    This study aimed to understand the molecular characteristics of buffalo leukemia inhibitory factor (BuLIF) and the generation of a stably transfected COS-1_BuLIF cell line for its functional characterization. Cumulus cells, isolated from oocytes, were separated, and total cDNA was prepared. The BuLIF gene was ligated into the cloning vector pJET1.2/blunt and expression vector pAcGFP-N1 which was transfected into COS-1 cells and confirmed by qRT-PCR and Western blot. BuLIF was immunoprecipitated and evaluated through a MTT assay. qRT-PCR of STAT3 was performed. The multiple sequence alignment of BuLIF showed high similarity with sheep (98.77%) and cattle (96.62%) compared with other species. The BuLIF gene has an open reading frame of 609 nucleotides coding for 202 amino acids. BuLIF was integrated into the genome of COS-1 cells and resulted in the formation of dome-like secondary structures which are indicative of its functional role mediated through STAT3 proteins. In conclusion, this cell line is suitable for understanding LIF-mediated biological functions. © 2017 S. Karger AG, Basel.

  18. Hydrothermal Synthesis and Electrochemical Properties of CoS2-Reduced Graphene Oxide Nanocomposite for Supercapacitor Application

    Science.gov (United States)

    Venkateshalu, Sandhya; Rangappa, Dinesh; Grace, Andrews Nirmala

    A Cobalt disulfide-reduced graphene oxide (CoS2-RGO) nanocomposite was prepared by a simple hydrothermal method and the prepared nanocomposite was characterized using various techniques like XRD, SEM and FTIR. The results of these techniques indicated the uniform deposition of CoS2 nanoparticles on Graphene sheets. Further, the prepared nanocomposites were tested for its activity towards energy storage and the test results showed a specific capacitance of 28F/g in an aqueous 20% KOH electrolyte at a current density of 0.5A/g. All these materials showed highly reversible charge-discharge cycles. The overall electrochemical performance of this composite is shown to be drastically improved when compared to bare CoS2 nanoparticles. Thus with the good electrochemical properties, CoS2-RGO nanocomposites could be effectively used as an electrode material for supercapacitors.

  19. Chinese Cooking.

    Science.gov (United States)

    Kane, Tony

    This unit, intended for secondary level students, is a general introduction to Chinese cooking. It is meant to inform students about the origins of Chinese cooking styles in their various regional manifestations, and it can be used to discuss how and why different cultures develop different styles of cooking. The first part of the unit, adapted…

  20. Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.

    Science.gov (United States)

    Nozaki, Mitsuki; Haraguchi, Shogo; Miyazaki, Takuro; Shigeta, Daichi; Kano, Noriko; Lei, Xiao-Feng; Kim-Kaneyama, Joo-Ri; Minakata, Hiroyuki; Miyazaki, Akira; Tsutsui, Kazuyoshi

    2018-02-01

    The COS-7 (CV-1 in Origin with SV40 genes) cells are known as non-steroidogenic cells because they are derived from kidney cells and the kidney is defined as a non-steroidogenic organ. Therefore, COS-7 cells are used for transfection experiments to analyze the actions of functional molecules including steroids. However, a preliminary study suggested that COS-7 cells metabolize [ 3 H]testosterone to [ 3 H]androstenedione. These results suggest that COS-7 cells are able to metabolize steroids. Therefore, the present study investigated the expression of steroidogenic enzymes and the metabolism of steroids in COS-7 cells. RT-PCR analyses demonstrated the expressions of several kinds of steroidogenic enzymes, such as cytochrome P450 side-chain cleavage enzyme, 3β-hydroxysteroid dehydrogenase/Δ 5 -Δ 4 isomerase, cytochrome P450 7α-hydroxylase, cytochrome P450 17α-hydroxylase/17,20-lyase, 17β-hydroxysteroid dehydrogenase, 5α-reductase, cytochrome P450 21-hydroxylase, cytochrome P450 11β-hydroxylase, and cytochrome P450 aromatase in COS-7 cells. In addition, steroidogenic enzymes 3β-HSD, P4507α, 5α-reductase, P450c17, P450c21, P450c11β, and 17β-HSD actively metabolized various steroids in cultured COS-7 cells. Finally, we demonstrated that 17β-HSD activity toward androstenedione formation was greater than other steroidogenic enzyme activities. Our results provide new evidence that COS-7 cells express a series of steroidogenic enzyme mRNAs and actively metabolize a variety of steroids.

  1. Bio-orthogonal "click-and-release" donation of caged carbonyl sulfide (COS) and hydrogen sulfide (H2S).

    Science.gov (United States)

    Steiger, Andrea K; Yang, Yang; Royzen, Maksim; Pluth, Michael D

    2017-01-24

    Hydrogen sulfide (H 2 S) is an important biomolecule with high therapeutic potential. Here we leverage the inverse-electron demand Diels-Alder (IEDDA) click reaction between a thiocarbamate-functionalized trans-cyclooctene and a tetrazine to deliver carbonyl sulfide (COS), which is quickly converted to H 2 S by the uniquitous enzyme carbonic anhydrase (CA), thus providing a new strategy for bio-orthogonal COS/H 2 S donation.

  2. Comparison of the Antimicrobial Properties of Chitosan Oligosaccharides (COS) and EDTA against Fusarium fujikuroi Causing Rice Bakanae Disease.

    Science.gov (United States)

    Kim, Seung Won; Park, Jae Kweon; Lee, Cho Heun; Hahn, Bum-Soo; Koo, Ja Choon

    2016-04-01

    Bakanae disease is a destructive rice disease in South Korea caused by Fusarium fujikuroi infection. Chemical fungicides have been used to manage the disease, but the emergence of fungicide-resistant strains has gradually increased. Two chelating agents, chitosan oligosaccharides (COS) and ethylenediaminetetraacetatic acid (EDTA), are well known as biosafe and biocompatible antimicrobial agents. In this study, we compared the actions of COS and EDTA to gain a better understanding of the underlying antimicrobial activities and to evaluate them as eco-friendly fungicides against F. fujikuroi. While COS exhibited a rapid fungicidal effect on hyphal growing cells within 5 min, EDTA had a fungistatic effect on reversible growth inhibition. Scanning electron microscopy revealed that COS treatment resulted in pore-formation and cellular leakage along the growing hyphae, whereas EDTA caused no significant morphological changes. COS activity was greatly suppressed by the addition of Ca(2+) to the medium, and EDTA action was largely suppressed by Mn(2+) and slightly by Ca(2+), respectively. Taken together, these results indicated that two chelating agents, COS and EDTA, have different modes of antimicrobial action on F. fujikuroi. Thus, the combination of chelating agents having different modes of action might be an effective disease management strategy to prevent or delay the development of fungicide-resistant strains.

  3. Three-dimensional hierarchical MoS2/CoS2 heterostructure arrays for highly efficient electrocatalytic hydrogen evolution

    Directory of Open Access Journals (Sweden)

    Canbin Ouyang

    2017-04-01

    Full Text Available Developing non-expensive, highly active and highly stable electrocatalysts for hydrogen evolution has aroused extensive attention, owing to the necessity of novel clean and sustainable energy carriers. In this paper, we report a synthesis of free-standing three-dimensional hierarchical MoS2/CoS2 heterostructure arrays through a convenient process. The investigation of electrocatalytic HER performance suggests that the MoS2/CoS2 hybrid catalyst exhibits significant enhancement in HER (onsetpotential and potential at a current density of 100 mA cm−2 are 20 mV and 125 mV, respectively and superior durability (no shift of current density is observed after a continuous scanning of 3000 times compared with individual CoS2 and MoS2. The superior HER performance was attributed to the formation of the interface between CoS2 and MoS2 through the electrochemical characterization, Raman, XPS analysis, and the control experiment. The lower onsetpotential, higher current density, excellent durability, and the free-standing structure of the three-dimensional hierarchical MoS2/CoS2 heterostructure array make it a promising cathode catalyst suitable for widespread application. Keywords: MoS2/CoS2, Heterostructure array, Free-standing, Hydrogen evolution reaction

  4. Imparting Cultural Values to Chinese Children through Literature

    Science.gov (United States)

    Zhang, Chenyi; Morrison, Johnetta W.

    2010-01-01

    Based on the occurrence of modernization and globalization in Chinese society over the last few decades, the content of 145 stories, published in the most popular Chinese children's story magazine from the 1980s to the present, were examined for the representation of cultural values. The presence of Chinese, Western and social-moral values in…

  5. Propagation of a general-type beam through a truncated fractional Fourier transform optical system.

    Science.gov (United States)

    Zhao, Chengliang; Cai, Yangjian

    2010-03-01

    Paraxial propagation of a general-type beam through a truncated fractional Fourier transform (FRT) optical system is investigated. Analytical formulas for the electric field and effective beam width of a general-type beam in the FRT plane are derived based on the Collins formula. Our formulas can be used to study the propagation of a variety of laser beams--such as Gaussian, cos-Gaussian, cosh-Gaussian, sine-Gaussian, sinh-Gaussian, flat-topped, Hermite-cosh-Gaussian, Hermite-sine-Gaussian, higher-order annular Gaussian, Hermite-sinh-Gaussian and Hermite-cos-Gaussian beams--through a FRT optical system with or without truncation. The propagation properties of a Hermite-cos-Gaussian beam passing through a rectangularly truncated FRT optical system are studied as a numerical example. Our results clearly show that the truncated FRT optical system provides a convenient way for laser beam shaping.

  6. Optics Express

    OpenAIRE

    Poon, Ting-Chung; Doh, K. B.

    2007-01-01

    The Hilbert transform as been investigated abundantly in coherent imaging. To the best of our knowledge, it is for the first time investigated in the context of incoherent imaging. We present a two-pupil optical heterodyne scanning system and analyze mathematically the design of its two pupils such that the optical system can perform the Hilbert transform on incoherent objects. Computer simulations of the idea clarify the theoretical results. (c) 2007 Optical Society of America.

  7. Publication rate of abstracts presented at the 2010 Canadian Ophthalmological Society Annual Meeting.

    Science.gov (United States)

    Basilious, Alfred; Benavides Vargas, Ana Maria; Buys, Yvonne M

    2017-08-01

    To evaluate the publication rate of submitted abstracts accepted for presentation at the 2010 Canadian Ophthalmological Society (COS) Annual Meeting in peer-reviewed journals. A retrospective analysis and literature search of abstracts presented at the 2010 COS Annual Meeting. Abstracts accepted as an oral presentation or poster from the 2010 COS Annual Meeting were tabulated by type of presentation (oral vs poster), subspecialty, study design, number of authors, and principal investigator's institution. A PubMed search was conducted for each abstract by key word, first author, and last author. The year of publication, journal, and impact factor were recorded for identified publications. Publication rate was calculated by type of presentation, subspecialty, study design, number of authors, and institution. A total of 175 abstracts were presented at the 2010 COS Annual Meeting. There were 105 oral (60%) and 70 poster (40%) presentations. The overall publication rate was 45.7%; 49.5% for oral presentations and 40.0% for posters. Cornea (57.6%) and public health (54.5%) had the highest publication rates of all subspecialties. Randomized control trials (71.4%) and cohort studies (70.0%) had higher publication rates than other study designs. Overall, 28.8% of abstracts were published in the Canadian Journal of Ophthalmology. The average impact factor of all publications was 2.73. Of abstracts presented at the 2010 COS Annual Meeting, 45.7% were published within 5 years after the conference. This publication rate is within the upper end of previously reported meeting publication rates for medical societies. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  8. Optical Coherence Tomography–Based Corneal Power Measurement and Intraocular Lens Power Calculation Following Laser Vision Correction (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Huang, David; Tang, Maolong; Wang, Li; Zhang, Xinbo; Armour, Rebecca L.; Gattey, Devin M.; Lombardi, Lorinna H.; Koch, Douglas D.

    2013-01-01

    Purpose: To use optical coherence tomography (OCT) to measure corneal power and improve the selection of intraocular lens (IOL) power in cataract surgeries after laser vision correction. Methods: Patients with previous myopic laser vision corrections were enrolled in this prospective study from two eye centers. Corneal thickness and power were measured by Fourier-domain OCT. Axial length, anterior chamber depth, and automated keratometry were measured by a partial coherence interferometer. An OCT-based IOL formula was developed. The mean absolute error of the OCT-based formula in predicting postoperative refraction was compared to two regression-based IOL formulae for eyes with previous laser vision correction. Results: Forty-six eyes of 46 patients all had uncomplicated cataract surgery with monofocal IOL implantation. The mean arithmetic prediction error of postoperative refraction was 0.05 ± 0.65 diopter (D) for the OCT formula, 0.14 ± 0.83 D for the Haigis-L formula, and 0.24 ± 0.82 D for the no-history Shammas-PL formula. The mean absolute error was 0.50 D for OCT compared to a mean absolute error of 0.67 D for Haigis-L and 0.67 D for Shammas-PL. The adjusted mean absolute error (average prediction error removed) was 0.49 D for OCT, 0.65 D for Haigis-L (P=.031), and 0.62 D for Shammas-PL (P=.044). For OCT, 61% of the eyes were within 0.5 D of prediction error, whereas 46% were within 0.5 D for both Haigis-L and Shammas-PL (P=.034). Conclusions: The predictive accuracy of OCT-based IOL power calculation was better than Haigis-L and Shammas-PL formulas in eyes after laser vision correction. PMID:24167323

  9. Electronic excitation of carbonyl sulphide (COS) by high-resolution vacuum ultraviolet photoabsorption and electron-impact spectroscopy in the energy region from 4 to 11 eV

    Energy Technology Data Exchange (ETDEWEB)

    Limão-Vieira, P., E-mail: plimaovieira@fct.unl.pt [Laboratório de Colisões Atómicas e Moleculares, CEFITEC, Departamento de Física, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica (Portugal); Department of Physics, Sophia University, Tokyo 102-8554 (Japan); Department of Physical Sciences, The Open University, Walton Hall, Milton Keynes MK7 6AA (United Kingdom); Ferreira da Silva, F.; Almeida, D. [Laboratório de Colisões Atómicas e Moleculares, CEFITEC, Departamento de Física, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica (Portugal); Hoshino, M.; Tanaka, H. [Department of Physics, Sophia University, Tokyo 102-8554 (Japan); Mogi, D. [Development and Marketing Department, New Products Development Division, Kanto Denka, Kogyo Co., Ltd., Chiyoda-ku, Tokyo 101-0063 (Japan); Tanioka, T. [Shibukawa Development Research Laboratory, New Products Development Division, Kanto Denka Kogyo Co., Ltd., Shibukawa City, Gunma 377-8513 (Japan); Mason, N. J. [Department of Physical Sciences, The Open University, Walton Hall, Milton Keynes MK7 6AA (United Kingdom); Hoffmann, S. V. [ISA, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Århus C (Denmark); Hubin-Franskin, M.-J.; Delwiche, J. [Départment de Chimie, Université de Liège, Institut de Chimie-Bât. B6C, allée de la Chimie 3, B-4000 Liège 1 (Belgium)

    2015-02-14

    The electronic state spectroscopy of carbonyl sulphide, COS, has been investigated using high resolution vacuum ultraviolet photoabsorption spectroscopy and electron energy loss spectroscopy in the energy range of 4.0–10.8 eV. The spectrum reveals several new features not previously reported in the literature. Vibronic structure has been observed, notably in the low energy absorption dipole forbidden band assigned to the (4π←3π) ({sup 1}Δ←{sup 1}Σ{sup +}) transition, with a new weak transition assigned to ({sup 1}Σ{sup −}←{sup 1}Σ{sup +}) reported here for the first time. The absolute optical oscillator strengths are determined for ground state to {sup 1}Σ{sup +} and {sup 1}Π transitions. Based on our recent measurements of differential cross sections for the optically allowed ({sup 1}Σ{sup +} and {sup 1}Π) transitions of COS by electron impact, the optical oscillator strength f{sub 0} value and integral cross sections (ICSs) are derived by applying a generalized oscillator strength analysis. Subsequently, ICSs predicted by the scaling are confirmed down to 60 eV in the intermediate energy region. The measured absolute photoabsorption cross sections have been used to calculate the photolysis lifetime of carbonyl sulphide in the upper stratosphere (20–50 km)

  10. Design and development of an ancient Chinese document recognition system

    Science.gov (United States)

    Peng, Liangrui; Xiu, Pingping; Ding, Xiaoqing

    2003-12-01

    The digitization of ancient Chinese documents presents new challenges to OCR (Optical Character Recognition) research field due to the large character set of ancient Chinese characters, variant font types, and versatile document layout styles, as these documents are historical reflections to the thousands of years of Chinese civilization. After analyzing the general characteristics of ancient Chinese documents, we present a solution for recognition of ancient Chinese documents with regular font-types and layout-styles. Based on the previous work on multilingual OCR in TH-OCR system, we focus on the design and development of two key technologies which include character recognition and page segmentation. Experimental results show that the developed character recognition kernel of 19,635 Chinese characters outperforms our original traditional Chinese recognition kernel; Benchmarked test on printed ancient Chinese books proves that the proposed system is effective for regular ancient Chinese documents.

  11. The coexistence of mitochondrial ND6 T14484C and 12S rRNA A1555G mutations in a Chinese family with Leber's hereditary optic neuropathy and hearing loss

    International Nuclear Information System (INIS)

    Wei Qiping; Zhou Xiangtian; Yang Li; Sun Yanhong; Zhou Jian; Li Guang; Jiang, Robert; Lu Fan; Qu Jia; Guan Minxin

    2007-01-01

    We report here the clinical, genetic and molecular characterization of one three-generation Han Chinese family with Leber's hereditary optic neuropathy (LHON) and hearing loss. Four of 14 matrilineal relatives exhibited the moderate central vision loss at the average age of 12.5 years. Of these, one subject exhibited both LHON and mild hearing impairment. Sequence analysis of the complete mitochondrial genomes in the pedigree showed the presence of homoplasmic LHON-associated ND6 T14484C mutation, deafness-associated 12S rRNA A1555 mutation and 47 other variants belonging to Eastern Asian haplogroup H2. None of other mitochondrial variants was evolutionarily conserved and functional significance. Therefore, the coexistence of the A1555G mutation and T14484C mutations in this Chinese family indicate that the A1555G mutation may play a synergistic role in the phenotypic manifestation of LHON associated ND6 T14484C mutation. However, the incomplete penetrance of vision and hearing loss suggests the involvement of nuclear modifier genes and environmental factors in the phenotypic expression of these mtDNA mutations

  12. Propofol protects against oxidative-stress-induced COS-7 cell apoptosis by inducing autophagy.

    Science.gov (United States)

    Yoon, Ji-Young; Baek, Chul-Woo; Kim, Eun-Jung; Park, Bong-Soo; Yu, Su-Bin; Yoon, Ji-Uk; Kim, Eok-Nyun

    2017-03-01

    In oxidative stress, reactive oxygen species (ROS) production contributes to cellular dysfunction and initiates the apoptotic cascade. Autophagy is considered the mechanism that decreases ROS concentration and oxidative damage. Propofol shows antioxidant properties, but the mechanisms underlying the effect of propofol preconditioning (PPC) on oxidative injury remain unclear. Therefore, we investigated whether PPC protects against cell damage from hydrogen peroxide (H 2 O 2 )-induced oxidative stress and influences cellular autophagy. COS-7 cells were randomly divided into the following groups: control, cells were incubated in normoxia (5% CO 2 , 21% O 2 , and 74% N 2 ) for 24 h without propofol; H 2 O 2 , cells were exposed to H 2 O 2 (400 µM) for 2 h; PPC + H 2 O 2 , cells pretreated with propofol were exposed to H 2 O 2 ; and 3-methyladenine (3-MA) + PPC + H 2 O 2 , cells pretreated with 3-MA (1 mM) for 1 h and propofol were exposed to H 2 O 2 . Cell viability was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide thiazolyl blue (MTT) reduction. Apoptosis was determined using Hoechst 33342 staining and fluorescence microscopy. The relationship between PPC and autophagy was detected using western blot analysis. Cell viability decreased more significantly in the H 2 O 2 group than in the control group, but it was improved by PPC (100 µM). Pretreatment with propofol effectively decreased H 2 O 2 -induced COS-7 cell apoptosis. However, pretreatment with 3-MA inhibited the protective effect of propofol during apoptosis. Western blot analysis showed that the level of autophagy-related proteins was higher in the PPC + H 2 O 2 group than that in the H 2 O 2 group. PPC has a protective effect on H 2 O 2 -induced COS-7 cell apoptosis, which is mediated by autophagy activation.

  13. Harmonious Society and Ecological Civilization: The concepts’ relationship

    OpenAIRE

    Balchindorzhieva O.B.; Tsyrendorzhieva D.Sh.

    2016-01-01

    The paper discusses a conceptual basis of a new course of development of the Chinese society that is aimed at sustainable development, solving the environmental pollution issues, achieving harmony in the society. The Chinese authorities proposed a new course of ‘ecological civilization’ development. The authors analyze the issues that arise from the development of ecological civilization in China from the perspective of definition of the term ‘ecological civilization’ in the context of tradit...

  14. Changes to the Spectral Extraction Algorithm at the Third COS FUV Lifetime Position

    Science.gov (United States)

    Taylor, Joanna M.; Azalee Bostroem, K.; Debes, John H.; Ely, Justin; Hernandez, Svea; Hodge, Philip E.; Jedrzejewski, Robert I.; Lindsay, Kevin; Lockwood, Sean A.; Massa, Derck; Oliveira, Cristina M.; Penton, Steven V.; Proffitt, Charles R.; Roman-Duval, Julia; Sahnow, David J.; Sana, Hugues; Sonnentrucker, Paule

    2015-01-01

    Due to the effects of gain sag on flux on the COS FUV microchannel plate detector, the COS FUV spectra will be moved in February 2015 to a pristine location on the detector, from Lifetime Position 2 (LP2) to LP3. The spectra will be shifted in the cross-dispersion (XD) direction by -2.5", about -31 pixels, from the original LP1. In contrast, LP2 was shifted by +3.5", about 41 pixels, from LP1. By reducing the LP3-LP1 separation compared to the LP2-LP1 separation, we achieve maximal spectral resolution at LP3 while preserving more detector area for future lifetime positions. In the current version of the COS boxcar extraction algorithm, flux is summed within a box of fixed height that is larger than the PSF. Bad pixels located anywhere within the extraction box cause the entire column to be discarded. At the new LP3 position the current extraction box will overlap with LP1 regions of low gain (pixels which have lost >5% of their sensitivity). As a result, large portions of spectra will be discarded, even though these flagged pixels will be located in the wings of the profiles and contain a negligible fraction of the total source flux. To avoid unnecessarily discarding columns affected by such pixels, an algorithm is needed that can judge whether the effects of gain-sagged pixels on the extracted flux are significant. The "two-zone" solution adopted for pipeline use was tailored specifically for the COS FUV data characteristics: First, using a library of 1-D spectral centroid ("trace") locations, residual geometric distortions in the XD direction are removed. Next, 2-D template profiles are aligned with the observed spectral image. Encircled energy contours are calculated and an inner zone that contains 80% of the flux is defined, as well as an outer zone that contains 99% of the flux. With this approach, only pixels flagged as bad in the inner 80% zone will cause columns to be discarded while flagged pixels in the outer zones do not affect extraction. Finally, all

  15. COS-B gamma ray sources beyond the predicted diffuse emission

    Science.gov (United States)

    Mayer-Hasselwander, H. A.; Simpson, G.

    1990-01-01

    COS-B data were reanalyzed using for background subtraction the modeled galactic diffuse gamma-ray emission based on HI- and CO-line surveys and the gamma-ray data itself. A methodology was developed for this purpose with the following three features: automatic generation of source catalogs using correlation analysis, simulation of trials to derive significance thresholds for source detection, and bootstrap sampling to drive error boxes and confidence intervals for source parameters. The analysis shows that about half of the 2CG sources are explained by concentrations in the distribution of molecular hydrogen. Indication for a few weak new sources is also obtained.

  16. The COS-B experiment and mission. [high energy extraterrestrial gamma radiation

    Science.gov (United States)

    1977-01-01

    The COS-B satellite carries a single experiment, capable of detecting gamma rays with energies greater than 30 MeV to study the spatial, energy, and time characteristics of high-energy radiation of galactic and extragalactic origin. The capability to search for gamma ray pulsations is enhanced by the inclusion in the payload of a proportional counter sensitive of X-rays of 2 to 12 keV. The experiment was calibrated using particle accelerators. The results of these measurements are presented, and the performance of the system in orbit is discussed.

  17. Analysis of the COS B data for evidence of linear polarization of Vela pulsar gamma rays

    Science.gov (United States)

    Mattox, John R.; Mayer-Hasselwander, Hans A.; Strong, Andy W.

    1990-01-01

    The COS B spark chamber telescope observations of the Vela pulsar were analyzed for gamma-ray polarization. No significant quadrupole moment is found in the azimuthal distribution of the electron-positron pair production planes. However, analysis of the sensitivity indicates that even 100-percent polarization would not be detected. Therefore, the null result does not constrain the polarization of the Vela pulsar gamma-ray emission. This result contradicts the report of Caraveo et al. (1988) of possible evidence for polarization of the Vela pulsar gamma rays.

  18. COS-B observations of the high-energy gamma radiation from the galactic disk

    Science.gov (United States)

    1977-01-01

    The COS-B experiment has observed approximately one-fourth of the galactic disk, including the galactic-center region, the galactic anticenter, and the Vela region. A completely automatic analysis of the events recorded during these observations reveals a galactic gamma ray emission from the three regions. In the galactic center and Vela regions, the disk emission distribution was measured. From these data, the existence of a local (less than 1 kpc) and a distant (greater than 3 kpc) emitting region is apparent in the general direction of the inner galaxy.

  19. COS-B observation of the milky way in high-energy gamma rays

    International Nuclear Information System (INIS)

    Mayer-Hasselwander, H.A.; Lebrun, F.; Masnou, J.L.

    1978-01-01

    The Caravane Collaboration's gamma-ray astronomy experiment aboard ESA's satellite COS-B has been recording celestial gamma rays in the energy range from about 50 MeV to several GeV since August 1975. These observations covers the whole range of galactic longitude, thus making it possible to present here the first complete detailed gamma-ray survey of the Milky Way with greatly improved statistical accuracy and significantly better energy measurement than in the previous survey. The present work concentrates on the spatial aspects of the gamma radiation, including localised sources

  20. Quantitative Metathesis in the Dialect of Cos: Ionic Influence or Local Feature?

    Directory of Open Access Journals (Sweden)

    Enrique Nieto Izquierdo

    2015-12-01

    Full Text Available In this paper the author discusses the adjective τέλεως and the «quantitative metathesis» of the type βασιλῆος > βασιλέως in the Ancient Greek Doric dialect of Cos. After presenting the available data, the author refutes the hypothesis that explain this feature as an influence of the nearby Ionic dialect and he provides arguments that prove that the «quantitative metathesis » is a local feature of the dialect of the island.

  1. Positive Effect of Heat Treatment on Carbon-Supported CoS Nanocatalysts for Oxygen Reduction Reaction

    Directory of Open Access Journals (Sweden)

    Haihong Zhong

    2015-07-01

    Full Text Available It is of increasing interest and an important challenge to develop highly efficient less-expensive cathode catalysts for anion-exchange membrane fuel cells (AEMFCs. In this work, we have directly prepared a carbon-supported CoS nanocatalyst in a solvothermal route and investigated the effect of heat-treatment on electrocatalytic activity and long-term stability using rotating ring-disk electrode (RRDE. The results show that the heat-treatment below 400 °C under nitrogen atmosphere significantly enhanced the electrocatalytic performance of CoS catalyst as a function of annealed temperature in terms of the cathodic current density, the half-wave potential, the HO2− product and the number of electrons transferred. The CoS catalyst that annealed at 400 °C (CoS-400 has exhibited a promising performance with the half-wave potential of 0.71 V vs. RHE (the highest one for non-precious metal chalcogenides, the minimum HO2− product of 4.3% at 0.60 V vs. RHE and close to the 4-electron pathway during the oxygen reduction reaction in 0.1 M KOH. Also, the CoS-400 catalyst has comparable durability to the Pt/C catalyst.

  2. Sulfur fertilization and fungal infections affect the exchange of H(2)S and COS from agricultural crops.

    Science.gov (United States)

    Bloem, Elke; Haneklaus, Silvia; Kesselmeier, Jürgen; Schnug, Ewald

    2012-08-08

    The emission of gaseous sulfur (S) compounds by plants is related to several factors, such as the plant S status or fungal infection. Hydrogen sulfide (H(2)S) is either released or taken up by the plant depending on the ambient air concentration and the plant demand for S. On the contrary, carbonyl sulfide (COS) is normally taken up by plants. In a greenhouse experiment, the dependence of H(2)S and COS exchange with ambient air on the S status of oilseed rape (Brassica napus L.) and on fungal infection with Sclerotinia sclerotiorum was investigated. Thiol contents were determined to understand their influence on the exchange of gaseous S compounds. The experiment revealed that H(2)S emissions were closely related to pathogen infections as well as to S nutrition. S fertilization caused a change from H(2)S consumption by S-deficient oilseed rape plants to a H(2)S release of 41 pg g(-1) (dw) min(-1) after the addition of 250 mg of S per pot. Fungal infection caused an even stronger increase of H(2)S emissions with a maximum of 1842 pg g(-1) (dw) min(-1) 2 days after infection. Healthy oilseed rape plants acted as a sink for COS. Fungal infection caused a shift from COS uptake to COS releases. The release of S-containing gases thus seems to be part of the response to fungal infection. The roles the S-containing gases may play in this response are discussed.

  3. Protocol for the development of a Core Outcome Set (COS) for hemorrhoidal disease: an international Delphi study.

    Science.gov (United States)

    van Tol, R R; Melenhorst, J; Dirksen, C D; Stassen, L P S; Breukink, S O

    2017-07-01

    Over the last decade, many studies were performed regarding treatment options for hemorrhoidal disease. Randomised controlled trials (RCTs) should have well-defined primary and secondary outcomes. However, the reported outcome measures are numerous and diverse. The heterogeneity of outcome definition in clinical trials limits transparency and paves the way for bias. The development of a core outcome set (COS) helps minimizing this problem. A COS is an agreed minimum set of outcomes that should be measured and reported in all clinical trials of a specific disease. The aim of this project is to generate a COS regarding the outcome of treatment after hemorrhoidal disease. A Delphi study will be performed by an international steering group healthcare professionals and patients with the intention to create a standard outcome set for future clinical trials for the treatment of hemorrhoidal disease. First, a literature review will be conducted to establish which outcomes are used in clinical trials for hemorrhoidal disease. Secondly, both healthcare professionals and patients will participate in several consecutive rounds of online questionnaires and a face-to-face meeting to refine the content of the COS. Development of a COS for hemorrhoidal disease defines a minimum outcome-reporting standard and will improve the quality of research in the future.

  4. Identificación in silico de un grupo de secuencias ortólogas conservadas (COS de Ipomoea batatas

    Directory of Open Access Journals (Sweden)

    Christian Solís Calero

    2013-03-01

    Full Text Available En el presente trabajo se describe una serie de procedimientos bioinformáticos para la predicción de un grupo secuencias ortólogas conservadas (COS de Ipomoea batatas, así como la evaluación de su potencial utilidad para la generación de marcadores moleculares y estudios de diversidad en esta especie. Con ese propósito usando los programas BLAST X y TBLASTN se realizó una comparación reciproca por similaridad entre secuencias ESTs procedentes de librerías de cDNAs de Ipomoea batatas, propias o disponibles de modo público en la base de datos GenBank, con secuencias COS de Arabidopsis thaliana. La anotación funcional de las secuencias COS predichas en Ipomoea batatas se realizo usando los programas BLASTX, INTERPROSCAN y PSI-BLAST. Se obtuvieron en total 204 secuencias COS candidatos de Ipomoea batatas, siendo 16 secuencias provenientes de una librería generada a partir de raíces de reserva. Se evaluó de modo computacional el polimorfismo de las secuencias COS de raíces de reserva, obteniéndose SNPs en 8 secuencias, y secuencias repetidas en tandem en una de ellas.

  5. Shoot Injury Increases the Level of Persistence of Salmonella enterica Serovar Sofia and Listeria innocua on Cos Lettuce and of Salmonella enterica Serovar Sofia on Chive.

    Science.gov (United States)

    Harapas, Dean; Premier, Robert; Tomkins, Bruce; Hepworth, Graham; Ajlouni, Said

    2015-12-01

    Minor shoot injury significantly (P cos lettuce in the greenhouse. Initial mean counts of the Salmonella on the injured and uninjured cos lettuce were on the order of 6 log CFU/g. After 3 days, the mean count decreased to 4.8 log CFU/g on the injured plants compared with the significantly (P cos lettuce and S. enterica serovar Sofia on chive. The findings reaffirm earlier results with Escherichia coli and increase the impetus to avoid shoot injury during the production of cos lettuce and chive, if bacteria of food safety concern are present.

  6. COS-7-based model: methodological approach to study John Cunningham virus replication cycle.

    Science.gov (United States)

    Prezioso, C; Scribano, D; Rodio, D M; Ambrosi, C; Trancassini, M; Palamara, A T; Pietropaolo, V

    2018-02-05

    John Cunningham virus (JCV) is a human neurotropic polyomavirus whose replication in the Central Nervous System (SNC) induces the fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML). JCV propagation and PML investigation have been severely hampered by the lack of an animal model and cell culture systems to propagate JCV have been very limited in their availability and robustness. We previously confirmed that JCV CY strain efficiently replicated in COS-7 cells as demonstrated by the progressive increase of viral load by quantitative PCR (Q-PCR) during the time of transfection and that archetypal regulatory structure was maintained, although two characteristic point mutations were detected during the viral cycle. This short report is an important extension of our previous efforts in defining our reliable model culture system able to support a productive JCV infection.Supernatants collected from transfected cells have been used to infect freshly seeded COS-7 cell line. An infectious viral progeny was obtained as confirmed by Western blot and immunofluorescence assay. During infection, the archetype regulatory region was conserved.Importantly, in this study we developed an improved culture system to obtain a large scale production of JC virus in order to study the genetic features, the biology and the pathogenic mechanisms of JC virus that induce PML.

  7. Ultrastructural and developmental evidence of phytotoxicity on cos lettuce (Lactuca sativa) associated with nonylphenol exposure.

    Science.gov (United States)

    de Bruin, Willeke; van der Merwe, Chris; Kritzinger, Quenton; Bornman, Riana; Korsten, Lise

    2017-02-01

    It has long been understood that the presence of endocrine disrupter chemicals (EDCs) in water can affect the reproductive, behavioural and regulatory systems of different types of mammals. Thus far, only a handful of studies have examined its impact on plant systems. Present research is limited to the potential uptake of these chemicals by plants and the general phytotoxic effects it can elicit. The aim of this study was to determine what effect an EDC has on developing plant and cell organelles and how it affects it. In this study, cos lettuce plants were exposed to different concentrations of nonylphenol (NP), an EDC, in a static hydroponic system. Changes in plant morphology, mass and length, chlorophyll content, as well as electrolyte leakage were examined. Furthermore an in-depth investigation of the plant cell ultrastructure was carried out with transmission electron microscopy. Results indicated that cos lettuce growth was severely restricted, chlorophyll content was reduced, leakage of electrolytes increased and roots were stunted especially after ≥3200 μg/l NP exposures. The structure of the rough endoplasmic reticulum, vacuole and chloroplast were also changed. This study emphasizes the importance of water quality management, since the presence of an EDC, like NP, can negatively impact the yield and internal structure of one of the world's most significant salad crops, namely lettuce. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Mechanistic and kinetic study on the catalytic hydrolysis of COS in small clusters of sulfuric acid.

    Science.gov (United States)

    Li, Kai; Song, Xin; Zhu, Tingting; Wang, Chi; Sun, Xin; Ning, Ping; Tang, Lihong

    2018-01-01

    The catalytic hydrolysis of carbonyl sulfide (COS) and the effect of small clusters of H 2 O and H 2 SO 4 have been studied by theoretical calculations. The addition of H 2 SO 4 could increase the enthalpy change (ΔHCOS + H 2 SO 4 -H 2 O) reaction has the lowest energy barrier of 29.97 kcal/mol. Although an excess addition of H 2 O and H 2 SO 4 increases the energy barrier, decreases the catalytic hydrolysis, which is consistent with experimental observations. The order of the energy barriers for the three reactions from low to high are as follows: COS + H 2 SO 4 -H 2 O COS + H 2 O + H 2 SO 4 -H 2 O COS + H 2 O+(H 2 SO 4 ) 2 . Kinetic simulations show that the addition of H 2 SO 4 can increase the reaction rate constants. Consequently, adding an appropriate amount of sulfuric acid promotes the catalytic hydrolysis of COS both kinetically and thermodynamically. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Implementation of a secure USIM COS architecture for mobile payment applications

    Science.gov (United States)

    Xiao, Juan; Wu, Juan; Xu, Donglai

    2017-01-01

    In this paper, a secure architecture for mobile payment applications is designed, which combines public service platform, Trusted Service Manager(TSM) and Security Element Financial Certification Security Domain(SE FCSD). The architecture interconnects various platforms, authenticates the identity of transaction parties and detects the legality of applications. In the architecture, a more reliable secure channel protocol SCP10 is used to secure the confidentiality and integrity of data. Using NFC Universal Subscriber Identifier Module Card (NFC USIM card) as the hardware platform, a security element supporting the architecture is implemented, and also a USIM Chip Operating System (USIM COS) supporting both financial certification security domain and SCP10 protocol is designed. In order to improve the efficiency of identity authentication of USIM card, a compact digital certification is adopted to improve verification speed and save storage space. The experiment results and security tests show that the USIM COS has advantages of security and reliability , and it has commercial value and has achieved effective mobile payments.

  10. Highly Active Catalyst of Two-Dimensional CoS2/Graphene Nanocomposites for Hydrogen Evolution Reaction.

    Science.gov (United States)

    Xing, Wei; Zhang, Yu; Xue, Qingzhong; Yan, Zifeng

    2015-12-01

    Hydrogen evolution reaction (HER) by electrochemical water splitting using new promising non-precious metal catalysts shows great potential for clean energy technology. The design and fabrication of a high-performance electrode material based on cobalt disulfide/reduced graphene oxide (CoS2/RGO) nanocomposites is reported by a one-step hydrothermal method. Benefiting from its structural advantages, namely, large amount of exposed surface, fast charge transfer, and synergistic effect between CoS2 and RGO, the as-prepared nanocomposites are exploited as a catalyst for the HER. The results indicate that CoS2/RGO-5 % exhibits the best performance of hydrogen evolution and the smallest overpotential of 159 mV to achieve a 15 mA cm(-2) current density, possessing the easiest releasing of hydrogen gas and the highest charge transfer rate, as well as remarkable stability.

  11. The Chinese Tiger Mother

    OpenAIRE

    Jacek Hołówka

    2011-01-01

    In 2010 a book by Amy Chua: Battle Hymn of the Tiger Mother was published and it sparked a broad discussion among pedagogues and the open society about the factors determining educational success. Chua forms a simple and provocative thesis – the Chinese mothers are the best in the world because they don’t spoil their children, quickly introduce them into the adult culture, have high expectations of them, they are brusque and cold but they teach their children how to survive and be competitive...

  12. Chinese Journalism Students

    DEFF Research Database (Denmark)

    Dombernowsky, Laura Møller

    2014-01-01

    As important providers of information, analysis of current events and debates, journalists are subject to high expectations regarding their professional values. Journalism is considered to be more than merely a career; it is construed as a profession that builds on personal commitment to serve...... society. This chapter is concerned with Chinese journalism students' self-perceptions and evaluations of journalistic performances in order to understand the professional values to which they adhere. The study is based on semi-structured in-depth interviews conducted in two periods in Spring 2011 and Fall...

  13. Staphylococcal pathogenicity island DNA packaging system involving cos-site packaging and phage-encoded HNH endonucleases.

    Science.gov (United States)

    Quiles-Puchalt, Nuria; Carpena, Nuria; Alonso, Juan C; Novick, Richard P; Marina, Alberto; Penadés, José R

    2014-04-22

    Staphylococcal pathogenicity islands (SaPIs) are the prototypical members of a widespread family of chromosomally located mobile genetic elements that contribute substantially to intra- and interspecies gene transfer, host adaptation, and virulence. The key feature of their mobility is the induction of SaPI excision and replication by certain helper phages and their efficient encapsidation into phage-like infectious particles. Most SaPIs use the headful packaging mechanism and encode small terminase subunit (TerS) homologs that recognize the SaPI-specific pac site and determine SaPI packaging specificity. Several of the known SaPIs do not encode a recognizable TerS homolog but are nevertheless packaged efficiently by helper phages and transferred at high frequencies. In this report, we have characterized one of the non-terS-coding SaPIs, SaPIbov5, and found that it uses two different, undescribed packaging strategies. SaPIbov5 is packaged in full-sized phage-like particles either by typical pac-type helper phages, or by cos-type phages--i.e., it has both pac and cos sites--a configuration that has not hitherto been described for any mobile element, phages included--and uses the two different phage-coded TerSs. To our knowledge, this is the first example of SaPI packaging by a cos phage, and in this, it resembles the P4 plasmid of Escherichia coli. Cos-site packaging in Staphylococcus aureus is additionally unique in that it requires the HNH nuclease, carried only by cos phages, in addition to the large terminase subunit, for cos-site cleavage and melting.

  14. Co3O4@CoS Core-Shell Nanosheets on Carbon Cloth for High Performance Supercapacitor Electrodes

    Science.gov (United States)

    Ning, Jinfeng; Zhang, Tianyu; He, Ying; Jia, Congpu; Saha, Petr; Cheng, Qilin

    2017-01-01

    In this work, a two-step electrodeposition strategy is developed for the synthesis of core-shell Co3O4@CoS nanosheet arrays on carbon cloth (CC) for supercapacitor applications. Porous Co3O4 nanosheet arrays are first directly grown on CC by electrodeposition, followed by the coating of a thin layer of CoS on the surface of Co3O4 nanosheets via the secondary electrodeposition. The morphology control of the ternary composites can be easily achieved by altering the number of cyclic voltammetry (CV) cycles of CoS deposition. Electrochemical performance of the composite electrodes was evaluated by cyclic voltammetry, galvanostatic charge–discharge and electrochemical impedance spectroscopy techniques. The results demonstrate that the Co3O4@CoS/CC with 4 CV cycles of CoS deposition possesses the largest specific capacitance 887.5 F·g−1 at a scan rate of 10 mV·s−1 (764.2 F·g−1 at a current density of 1.0 A·g−1), and excellent cycling stability (78.1% capacitance retention) at high current density of 5.0 A·g−1 after 5000 cycles. The porous nanostructures on CC not only provide large accessible surface area for fast ions diffusion, electron transport and efficient utilization of active CoS and Co3O4, but also reduce the internal resistance of electrodes, which leads to superior electrochemical performance of Co3O4@CoS/CC composite at 4 cycles of CoS deposition. PMID:28772968

  15. Co3O4@CoS Core-Shell Nanosheets on Carbon Cloth for High Performance Supercapacitor Electrodes

    Directory of Open Access Journals (Sweden)

    Jinfeng Ning

    2017-06-01

    Full Text Available In this work, a two-step electrodeposition strategy is developed for the synthesis of core-shell Co3O4@CoS nanosheet arrays on carbon cloth (CC for supercapacitor applications. Porous Co3O4 nanosheet arrays are first directly grown on CC by electrodeposition, followed by the coating of a thin layer of CoS on the surface of Co3O4 nanosheets via the secondary electrodeposition. The morphology control of the ternary composites can be easily achieved by altering the number of cyclic voltammetry (CV cycles of CoS deposition. Electrochemical performance of the composite electrodes was evaluated by cyclic voltammetry, galvanostatic charge–discharge and electrochemical impedance spectroscopy techniques. The results demonstrate that the Co3O4@CoS/CC with 4 CV cycles of CoS deposition possesses the largest specific capacitance 887.5 F·g−1 at a scan rate of 10 mV·s−1 (764.2 F·g−1 at a current density of 1.0 A·g−1, and excellent cycling stability (78.1% capacitance retention at high current density of 5.0 A·g−1 after 5000 cycles. The porous nanostructures on CC not only provide large accessible surface area for fast ions diffusion, electron transport and efficient utilization of active CoS and Co3O4, but also reduce the internal resistance of electrodes, which leads to superior electrochemical performance of Co3O4@CoS/CC composite at 4 cycles of CoS deposition.

  16. Templates of "Chineseness" and Trajectories of Cambodian Chinese Entrepreneurship in Phnom Penh

    Directory of Open Access Journals (Sweden)

    Michiel Verver

    2012-09-01

    Full Text Available In the 1960s, William Willmott described Cambodia as a plural society in which different ethnic groups occupy different places in the economic structure. The Chinese made up the economic class, active in trade and commerce, and formed a definable ethnic community, both socioculturally and politically. Since Willmott’s seminal studies, Cambodia’s ethnic Chinese have endured the destruction and repression of both private enterprise and Chinese sociocultural life (1970–1990, followed by a revitalization of Chinese business. Through ethnographic case studies, this paper explores the relationship between “Chineseness” and business life in trajectories of Cambodian Chinese entrepreneurship in Phnom Penh. How do entrepreneurs deploy notions of Chinese business? The author argues that Chinese family businesses, trust-based networks, patronage arrangements, and cultural representations have indeed been greatly revitalized over the last few decades, but that they also remain challenged in certain contexts. Moreover, such revitalization has taken a fundamentally different form from Willmott’s description. Practices of Chinese business can no longer be ascribed to an ethnic Chinese “community” in Phnom Penh. Rather, as the latter has become increasingly multiform, Chinese business has developed into a template at the deployment (or neglect of a broader category of Cambodian Chinese entrepreneurs.

  17. A Benchmark Approach of Counterparty Credit Exposure of Bermudan Option under Lévy Process : The Monte Carlo-COS Method

    NARCIS (Netherlands)

    Shen, Y.; Van der Weide, J.A.M.; Anderluh, J.H.M.

    2013-01-01

    An advanced method, which we call Monte Carlo-COS method, is proposed for computing the counterparty credit exposure profile of Bermudan options under Lévy process. The different exposure profiles and exercise intensity under different mea- sures, P and Q, are discussed. Since the COS method [1

  18. Two-Layer 16 Tesla Cosθ Dipole Design for the FCC

    Energy Technology Data Exchange (ETDEWEB)

    Holik, Eddie Frank [Fermilab; Ambrosio, Giorgio [Fermilab; Apollinari, G. [Fermilab

    2018-02-13

    The Future Circular Collider or FCC is a study aimed at exploring the possibility to reach 100 TeV total collision energy which would require 16 tesla dipoles. Upon the conclusion of the High Luminosity Upgrade, the US LHC Accelerator Upgrade Pro-ject in collaboration with CERN will have extensive Nb3Sn magnet fabrication experience. This experience includes robust Nb3Sn conductor and insulation scheming, 2-layer cos2θ coil fabrication, and bladder-and-key structure and assembly. By making im-provements and modification to existing technology the feasibility of a two-layer 16 tesla dipole is investigated. Preliminary designs indicate that fields up to 16.6 tesla are feasible with conductor grading while satisfying the HE-LHC and FCC specifications. Key challenges include accommodating high-aspect ratio conductor, narrow wedge design, Nb3Sn conductor grading, and especially quench protection of a 16 tesla device.

  19. Cyg X-3: Not seen in high-energy gamma rays by COS-B

    Science.gov (United States)

    Hermsen, W.; Bennett, K.; Bignami, G. F.; Bloemen, J. B. G. M.; Buccheri, R.; Caraveo, P. A.; Mayer-Hasselwander, H. A.; Oezel, M. E.; Pollock, A. M. T.; Strong, A. W.

    1985-01-01

    COS-B had Cyg X-3 within its field of view during 7 observation periods between 1975 and 1982 for in total approximately 300 days. In the skymaps (70 meV E 5000 meV) of the Cyg-X region produced for each of these observations and in the summed map, a broad complex structure is visible in the region 72 deg approximately less than 1 approximately less than 85 deg, approximately less than 5 deg. No resolved source structure is visible at the position of Cyg X-3, but a weak signal from Cyg X-3 could be hidden in the structured gamma-ray background. Therefore, the data has been searched for a 4.8 h timing signature, as well as for a source signal in the sky map in addition to the diffuse background structure as estimated from tracers of atomic and molecular gas.

  20. HST/COS Observations of 10 Quasar Outflows in the Extreme UV: AGN Feedback

    Science.gov (United States)

    Reid Miller, Timothy; Arav, Nahum; Xu, Xinfeng

    2018-01-01

    Quasars and Seyferts show ubiquitous outflows where blue-shifted absorption lines are attributed to sub-relativistic (~103-104 km/s) mass ejections. These outflows are prime candidates for producing various AGN feedback processes: curtailing the growth of the host galaxy, explaining the relationship between the masses of the central black hole and the host galaxy, and chemical enrichment of the intergalactic and intracluster medium. HST COS observations from Cycle 24 program GO14777 allowed for the first time a sample of quasar outflows covering the diagnostic-rich 500-1050 Angstrom rest-frame (EUV) wavelength range. Initial results on the distances and energetics of the observed outflows are presented here.

  1. Quantitative Metathesis in the Dialect of Cos: Ionic Influence or Local Feature?

    OpenAIRE

    Enrique Nieto Izquierdo

    2015-01-01

    En este trabajo se discute el adjetivo τέλεως y la llamada «metátesis de cantidad» (βασιλῆος > βασιλέως) en el antiguo dialecto dorio de Cos. Tras presentar los datos de que disponemos, el autor rechaza las teorías que atribuyen el fenómeno a un influjo del dialecto jonio y aporta argumentos que muestran que se trata con toda probabilidad de un proceso autóctono de la isla In this paper the author discusses the adjective τέλεως and the «quantitative metathesis» of the type βασι...

  2. The Amazing COS FUV (1320 - 1460 A) Spectrum of (lambda) Vel (K4Ib-II)

    Science.gov (United States)

    Carpenter, Kenneth

    2010-01-01

    The FUV spectrum (1320-1460 A) of the K4 lb-11 supergiant (lambda) Vel was observed with the Cosmic Origins Spectrograph (COS) on HST, as part of the Ayres and Redfield Cycle 17 SNAP program "SNAPing Coronal Iron". This spectrum covers a region not previously recorded in (lambda) Vel at high resolution and, in a mere 20 minutes of exposure, reveals a treasure trove of information. It shows a wide variety of strong emission lines, superposed on a bright continuum, with contributions from both atomic and molecular species. Multiple absorptions, including numerous Ni II and Fe II lines, are visible over this continuum, which is likely generated in the chromosphere of the star. Evidence of the stellar wind is seen in the P Cygni profiles of the CII lines near 1335 A and the results of fluorescence processes are visible throughout the region. The spectrum has remarkable similarities to that of (alpha) Boo (K1.5 III), but significant differences as well, including substantial FUV continuum emission, reminiscent of the M2 Iab supergiant (alpha) Ori, but minus the CO fundamental absorption bands seen in the spectrum of the latter star. However, fluoresced CO emission is present, as in the K-giant stars (alpha) Boo and (alpha) Tau (K5 III). The presence of hot plasma in the atmosphere of the star, indicated by previous GHRS observations of Si III] and C III] lines near 1900 A and FUSE observations of O VI 1032 A, is further confirmed by the detection in this COS spectrum of the Si IV UV 1 lines near 1400 A, though both lines are contaminated by overlying fluorescent H2 emission. We present the details of this spectrum, in comparison with stars of similar temperature or luminosity and discuss the implications for the structure of, and the radiative processes active in, the outer atmospheres of these stars.

  3. Flickering AGN can explain the strong circumgalactic O VI observed by COS-Halos

    Science.gov (United States)

    Oppenheimer, Benjamin D.; Segers, Marijke; Schaye, Joop; Richings, Alexander J.; Crain, Robert A.

    2018-03-01

    Proximity zone fossils (PZFs) are ionization signatures around recently active galactic nuclei (AGNs) where metal species in the circumgalactic medium remain overionized after the AGNs have shut off due to their long recombination time scales. We explore cosmological zoom hydrodynamic simulations, using the EAGLE (Evolution and Assembly of GaLaxies and their Environments) model paired with a non-equilibrium ionization and cooling module including time-variable AGN radiation to model PZFs around star-forming disc galaxies in the z ˜ 0.2 Universe. Previous simulations typically underestimated the O VI content of galactic haloes, but we show that plausible PZF models increase O VI column densities by 2 - 3 × to achieve the levels observed around COS-Halos star-forming galaxies out to 150 kpc. Models with AGN bolometric luminosities ≳ 1043.6erg s- 1, duty cycle fractions ≲ 10 per cent, and AGN lifetimes ≲ 106 yr are the most promising, because their supermassive black holes grow at the cosmologically expected rate and they mostly appear as inactive AGN, consistent with COS-Halos. The central requirement is that the typical star-forming galaxy hosted an active AGN within a time-scale comparable to the recombination time of a high metal ion, which for circumgalactic O VI is ≈107 yr. H I, by contrast, returns to equilibrium much more rapidly due to its low neutral fraction and does not show a significant PZF effect. O VI absorption features originating from PZFs appear narrow, indicating photoionization, and are often well aligned with lower metal ion species. PZFs are highly likely to affect the physical interpretation of circumgalactic high ionization metal lines if, as expected, normal galaxies host flickering AGN.

  4. Genomics in cereals: from genome-wide conserved orthologous set (COS) sequences to candidate genes for trait dissection.

    Science.gov (United States)

    Quraishi, Umar Masood; Abrouk, Michael; Bolot, Stéphanie; Pont, Caroline; Throude, Mickael; Guilhot, Nicolas; Confolent, Carole; Bortolini, Fernanda; Praud, Sébastien; Murigneux, Alain; Charmet, Gilles; Salse, Jerome

    2009-11-01

    Recent updates in comparative genomics among cereals have provided the opportunity to identify conserved orthologous set (COS) DNA sequences for cross-genome map-based cloning of candidate genes underpinning quantitative traits. New tools are described that are applicable to any cereal genome of interest, namely, alignment criterion for orthologous couples identification, as well as the Intron Spanning Marker software to automatically select intron-spanning primer pairs. In order to test the software, it was applied to the bread wheat genome, and 695 COS markers were assigned to 1,535 wheat loci (on average one marker/2.6 cM) based on 827 robust rice-wheat orthologs. Furthermore, 31 of the 695 COS markers were selected to fine map a pentosan viscosity quantitative trait loci (QTL) on wheat chromosome 7A. Among the 31 COS markers, 14 (45%) were polymorphic between the parental lines and 12 were mapped within the QTL confidence interval with one marker every 0.6 cM defining candidate genes among the rice orthologous region.

  5. RAINBOW TROUT ANDROGEN RECEPTOR ALPHA AND THE HUMAN ANDROGEN RECEPTOR: COMPARISONS IN THE COS WHOLE CELL BINDING ASSAY

    Science.gov (United States)

    Rainbow Trout Androgen Receptor Alpha And Human Androgen Receptor: Comparisons in the COS Whole Cell Binding Assay Mary C. Cardon, L. Earl Gray, Jr. and Vickie S. WilsonU.S. Environmental Protection Agency, ORD, NHEERL, Reproductive Toxicology Division, Research Triangle...

  6. Estimate of the penetrance of BRCA mutation and the COS software for the assessment of BRCA mutation probability.

    Science.gov (United States)

    Berrino, Jacopo; Berrino, Franco; Francisci, Silvia; Peissel, Bernard; Azzollini, Jacopo; Pensotti, Valeria; Radice, Paolo; Pasanisi, Patrizia; Manoukian, Siranoush

    2015-03-01

    We have designed the user-friendly COS software with the intent to improve estimation of the probability of a family carrying a deleterious BRCA gene mutation. The COS software is similar to the widely-used Bayesian-based BRCAPRO software, but it incorporates improved assumptions on cancer incidence in women with and without a deleterious mutation, takes into account relatives up to the fourth degree and allows researchers to consider an hypothetical third gene or a polygenic model of inheritance. Since breast cancer incidence and penetrance increase over generations, we estimated birth-cohort-specific incidence and penetrance curves. We estimated breast and ovarian cancer penetrance in 384 BRCA1 and 229 BRCA2 mutated families. We tested the COS performance in 436 Italian breast/ovarian cancer families including 79 with BRCA1 and 27 with BRCA2 mutations. The area under receiver operator curve (AUROC) was 84.4 %. The best probability threshold for offering the test was 22.9 %, with sensitivity 80.2 % and specificity 80.3 %. Notwithstanding very different assumptions, COS results were similar to BRCAPRO v6.0.

  7. Kinetic study of COS with tertiary alkanolamine solutions 2. Modelling and experiments in a stirred cell reactor

    NARCIS (Netherlands)

    Littel, R.J.; Littel, R.J.; Versteeg, Geert; van Swaaij, Willibrordus Petrus Maria

    1992-01-01

    Absorption experiments of COS into aqueous solutions of MDEA and DEMEA at 303 K have been carried out in a stirred cell reactor. An absorption model, based on Higbie’s penetration theory, has been developed and applied to interpret the absorption experiments, using the kinetic data obtained in part

  8. Kinetic Study of COS with Tertiary Alkanolamine Solutions. 2. Modeling and Experiments in a Stirred Cell Reactor

    NARCIS (Netherlands)

    Littel, Rob J.; Versteeg, Geert F.; Swaaij, Wim P.M. van

    1992-01-01

    Absorption experiments of COS into aqueous solutions of MDEA and DEMEA at 303 K have been carried out in a stirred cell reactor. An absorption model, based on Higbie’s penetration theory, has been developed and applied to interpret the absorption experiments, using the kinetic data obtained in part

  9. Synthesis of tremella-like CoS and its application in sensing of hydrogen peroxide and glucose.

    Science.gov (United States)

    Wu, Wenqin; Yu, Beibei; Wu, Huimin; Wang, Shengfu; Xia, Qinghua; Ding, Yu

    2017-01-01

    Different phases of cobalt sulfides have been fabricated by one-pot hydrothermal method. Comparing all of the prepared materials, and the results revealed that CoS was the most conductive and could accelerate electron transfer. The CoS presented tremella-like and excellent catalytic activities towards hydrogen peroxide and glucose. The sensor based on CoS performed amperometric sensing of hydrogen peroxide in a linear range between 5.00μM and 14.82mM. Meanwhile, sensing of glucose with double-linear range, one is between 5.00μM and 1.10mM, the other is between 1.20mM and 10.20mM. These due to the fact that more and more intermediate species absorb onto electrode surface with increasing the concentration of glucose, which limit the following glucose oxidation. Furthermore, the hydrogen peroxide and glucose sensors based on tremella-like CoS also exhibited excellent selectivity, stability, and reproducibility. Thus, the sensor showed potential utilities in hydrogen peroxide and glucose detection. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. CoS acicular nanorod arrays for the counter electrode of an efficient dye-sensitized solar cell.

    Science.gov (United States)

    Kung, Chung-Wei; Chen, Hsin-Wei; Lin, Chia-Yu; Huang, Kuan-Chieh; Vittal, R; Ho, Kuo-Chuan

    2012-08-28

    One-dimensional cobalt sulfide (CoS) acicular nanorod arrays (ANRAs) were obtained on a fluorine-doped tin oxide (FTO) substrate by a two-step approach. First, Co(3)O(4) ANRAs were synthesized, and then they were converted to CoS ANRAs for various periods. The compositions of the films obtained after various conversion periods were verified by X-ray diffraction, UV-visible spectrophotometry, and X-ray photoelectron spectroscopy; their morphologies were examined at different periods by scanning electron microscopic and transmission electron microscopic images. Electrocatalytic abilities of the films toward I(-)/I(3)(-) were verified through cyclic voltammetry (CV) and Tafel polarization curves. Long-term stability of the films in I(-)/I(3)(-) electrolyte was studied by CV. The FTO substrates with CoS ANRAs were used as the counter electrodes for dye-sensitized solar cells; a maximum power conversion efficiency of 7.67% was achieved for a cell with CoS ANRAs, under 100 mW/cm(2), which is nearly the same as that of a cell with a sputtered Pt counter electrode (7.70%). Electrochemical impedance spectroscopy was used to substantiate the photovoltaic parameters.

  11. ACTIVATION ASSAY FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR- ALPHA (PPARÁ) BY PERFLUOROALKYL ACIDS (PFAAS) IN COS-1 CELLS

    Science.gov (United States)

    PFAAs have been found to elicit various physiological effects including peroxisome proliferation, indicating the mechanism of action for these chemicals could involve PPAR. This study investigates the ability of PFAAs to bind and activate mouse and human PPARα in COS-1 cell...

  12. BINDING OF STEROIDS AND ENVIRONMENTAL CHEMICALS TO THE RAINBOW TROUT ANDROGEN RECEPTOR ALPHA EXPRESSED IN COS CELLS

    Science.gov (United States)

    Binding of Steroids and Environmental Chemicals to the Rainbow Trout Androgen Receptor Alpha Expressed in COS Cells. Mary C. Cardon, L. Earl Gray. Jr., Phillip C. Hartig and Vickie S. Wilson U.S. Environmental Protection Agency, ORD, NHEERL, Reproductive Toxicology...

  13. Optical biosensors.

    Science.gov (United States)

    Damborský, Pavel; Švitel, Juraj; Katrlík, Jaroslav

    2016-06-30

    Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surface-enhanced Raman scattering biosensors. The optical biosensors discussed here allow the sensitive and selective detection of a wide range of analytes including viruses, toxins, drugs, antibodies, tumour biomarkers and tumour cells. © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  14. Expression of rat oligodendrocyte transcription factor 2 in COS-7 cells following its eukaryotic expression vector construction.

    Science.gov (United States)

    Qu, D-W; Han, X-J; Wang, Y-L; Xu, H-S

    2014-08-01

    The basic HLH transcription factor Olig is a key regulator for differentiating the oligodendrocyte lineage cells during development. Oligodendrocyte transcription factor 2 (Olig2) plays a crucial role in differentiating the oligodendrocytes in the spinal cord. We aimed to construct and investigate the eukaryotic expression recombinant plasmid in the rat Olig2. The experiment was performed at the Laboratory of Neurobiology, Xuzhou Medical College from October 2011 to March 2012. The pEGFP-N1 vector was purchased from Invitrogen. JM101 competent cells and COS-7 cells were preserved at the Laboratory of Neurobiology, Xuzhou Medical College, China. The Olig2 cDNA fragment was cloned by RT-PCR with the total RNA from the neonatal rat spinal cord, and subsequently cloned into pGEM-T vector. The confirmed Olig2 fragment was then cloned into the pEGFP-N1 vector. The right recombinant was transfected into COS-7 cells by lipofectamine 2000. The expression of the Olig2 in COS-7 cells was detected by RT-PCR and immunoblot analysis. Enzyme digestion and sequencing of the recombinant plasmid; and expression of the Olig2 were analyzed by fluorescence microscope and western blot. The correct pEGFP-N1-Olig2 cloning was verified by restriction endonuclease digestion and sequencing. The western blot analysis indicated that the Olig2-GFP fusion protein was expressed in the COS-7/pEGFP-N1-Olig2 cells at 72 h. The pEGFP-N1-Olig2 vector was constructed successfully. The Olig2-GFP fusion protein was expressed in the COS-7/pEGFP-N1-Olig2 cells. This study lays the foundation for further research in gene therapy for central nervous system demyelinating diseases.

  15. Optical enhancement effects of plasmonic nanostructures on organic photovoltaic cells

    KAUST Repository

    Park, Hui Joon

    2015-04-01

    © 2015 Hui Joon Park and L. Jay Guo. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved. In this article, the optical enhancement effects of plasmonic nanostructures on OPV cells were reviewed as an effective way to resolve the mismatch problems between the short exciton diffusion length in organic semiconductors (around 10 nm) and the large thickness required to fully absorb sunlight (e.g. hundreds of nanometers). Especially, the performances of OPVs with plasmonic nanoparticles in photoactive and buffer layers and with periodic nanostructures were investigated. Furthermore, nanoimprint lithography-based nanofabrication processes that can easily control the dimension and uniformity of structures for large-area and uniform plasmonic nanostructures were demonstrated.

  16. Chinese restaurant syndrome

    Science.gov (United States)

    Chinese restaurant syndrome is a set of symptoms that some people have after eating Chinese food. A food additive ... Chinese restaurant syndrome is most often diagnosed based on the symptoms. The health care provider may ask the following ...

  17. The Chinese path to individualization.

    Science.gov (United States)

    Yan, Yunxiang

    2010-09-01

    This article explores the rise of the individual and the consequential individualization of society which should be viewed as a reflexive part of China's state-sponsored quest for modernity. It traces the origin of the individualization process to the Maoist era, arguing that some collectivist programmes of social engineering and the socialist path of modernization under Maoism ironically resulted in a partial individualization of Chinese society. Examining profound social changes during the three decades of the post-Mao reforms, the article reveals a number of similarities with the individualization process in Western Europe but also demonstrates some important differences. In the last section, the theoretical implications of the Chinese case in light of Ulrich Beck's theory of individualization and second modernity are discussed. © London School of Economics and Political Science 2010.

  18. Ecological civilization and Chinese philosophy

    OpenAIRE

    Balchindorjieva O.B.

    2016-01-01

    the author raises the problem of the construction of ecological civilization in China in terms of the definition of «ecological civilization» in the context of traditional Chinese culture in its relationship with the traditional and the modern understanding of harmony and harmonious society, and the development of regulation in the sphere of environmental protection. In the article the analysis of philosophical aspects of this problem is given. The author demonstrates the approach developed b...

  19. Effect of myopia on ganglion cell complex and peripapillary retinal nerve fibre layer measurements: a Fourier-domain optical coherence tomography study of young Chinese persons.

    Science.gov (United States)

    Zhao, Zhennan; Jiang, Chunhui

    2013-08-01

    To investigate the change of the ganglion cell complex and peripapillary retinal nerve fibre layer under different refractive conditions, as measured by optical coherence tomography. Cross-sectional observational study. A total of 107 eyes from 107 subjects were studied. Ganglion cell complex and retinal nerve fibre layer were studied by a spectral-domain system. Their relationship against spherical equivalents and axial length was studied. The thickness of ganglion cell complex and retinal nerve fibre layer at different area and under different refractive conditions as measurements by optical coherence tomography. The average, superior and inferior macular ganglion cell complex thickness was significantly associated with both spherical equivalents (all P fibre layer thicknesses from the superior, inferior and temporal quadrants were associated with both spherical equivalents (all P fibre layer thickness was studied in sections, then some parts of the upper and lower temporal part showed no correlation with either spherical equivalents or axial length (all P fibre layer were correlated with refraction and axial length. Therefore, when using these for clinical purposes, attention must be paid to the refractive state of the patient. © 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.

  20. History of modern optics ad optoelectronics development in China

    CERN Document Server

    Tian, Shouyun

    2014-01-01

    This book presents a collection of memoir papers on the development of modern and contemporary optics and optoelectronics in China from the 18th to 20th centuries. The papers were written by famous scientists in China, including members of the Chinese Academy of Sciences and the Chinese Academy of Engineering, sharing their experience in different fields of optics and optoelectronics development. This is a unique book in understanding the natural science history of optics and optoelectronics. It gives you the general idea about how the western optical science spread to China in the 17th to 18th century; the cradle of the contemporary optics in China; Birth, development and application of lasers in China; high energy and high power lasers for laser antiballistic missile and laser nuclear fusion; development of Chinese optical communication and optical information storage; laser and infrared optics research for space science; development of Chinese optical instruments, etc.

  1. Dual repression of the multidrug efflux pump CmeABC by CosR and CmeR in Campylobacter jejuni

    Directory of Open Access Journals (Sweden)

    Tara Grinnage-Pulley

    2016-07-01

    Full Text Available During transmission and intestinal colonization, Campylobacter jejuni, a major foodborne human pathogen, experiences oxidative stress. CosR, a response regulator in C. jejuni, modulates the oxidative stress response and represses expression of the CmeABC multidrug efflux pump. CmeABC, a key component in resistance to toxic compounds including antimicrobials and bile salts, is also under negative regulation by CmeR, a TetR family transcriptional regulator. How CosR and CmeR interact in binding to the cmeABC promoter and how CosR senses oxidative stress are still unknown. To answer these questions, we conducted various experiments utilizing electrophoretic mobility shift assays and transcriptional fusion assays. CosR and CmeR bound independently to two separate sites of the cmeABC promoter, simultaneously repressing cmeABC expression. This dual binding of CosR and CmeR is optimal with a 17 base pair space between the two binding sites as mutations that shortened the distance between the binding sites decreased binding by CmeR and enhanced cmeABC expression. Additionally, the single cysteine residue (C218 of CosR was sensitive to oxidation, which altered the DNA-binding activity of CosR and dissociated CosR from the cmeABC promoter as determined by electrophoretic mobility shift assay. Replacement of C218 with serine rendered CosR insensitive to oxidation, suggesting a potential role of C218 in sensing oxidative stress and providing a possible mechanism for CosR-mediated response to oxidative stress. These findings reveal a dual regulatory role of CosR and CmeR in modulating cmeABC expression and suggest a potential mechanism that may explain overexpression of cmeABC in response to oxidative stress. Differential expression of cmeABC mediated by CmeR and CosR in response to different signals may facilitate adaptation of Campylobacter to various environmental conditions.

  2. School Experience of Chinese Sexual Minority Students in Hong Kong

    Science.gov (United States)

    Kwok, Diana K.

    2016-01-01

    Heterosexism faced by sexual minority (lesbian, gay, bisexual, and queer/questioning [LGBQ]) students has been extensively studied internationally in the past 2 decades but has only recently received attention from Hong Kong Chinese society. Chinese LGBQ students are not guaranteed to be included in Hong Kong schools, where antidiscrimination…

  3. Chinese and related North American herbs: phytopharmacology and therapeutic values

    National Research Council Canada - National Science Library

    Li, Thomas S. C

    2002-01-01

    ..., most particularly Chinese herbs. Unfortunately, while there is an incredible wealth of knowledge about Chinese herbs, most of this information has been unavailable to Western society, and even the accessible information has often been in obscure sources. The famous 15th century physician Paracelsus taught that the only difference between a medi...

  4. Birth Cohort Changes in Chinese College Students' Loneliness and Social Support

    Science.gov (United States)

    Xin, Sufei; Xin, Ziqiang

    2016-01-01

    With the dramatic recent changes in Chinese society, Chinese college students' average levels of loneliness and social support might also have changed across their birth cohorts. The present cross-temporal meta-analysis of 56 studies (N = 21,541) found that Chinese college students' scores on the UCLA Loneliness Scale (Version 3) increased…

  5. Etnisch ondernemerschap : de Chinese horecasector in Nederland en in de Verenigde Staten van Amerika

    NARCIS (Netherlands)

    Rijkschroeff, Boudewijn Roger

    1998-01-01

    Chinese cuisine has become very familiar to Dutch society in the past few decades. Although there already existed a handful of Chinese restaurants in the Netherlands shortly after the Second World War, it was not until the 1970s that the Chinese restaurant and catering sector began to bloom. In

  6. Older Chinese women immigrants and their leisure experiences: before and after emigration to the United States

    Science.gov (United States)

    Ching-Hua Ho; Jaclyn A. Card

    2002-01-01

    The concept of leisure has generally focused on men. This is especially true in Chinese society where women seldom have the right to speak about leisure or mention leisure activities. For many Chinese women, the integration of household and leisure has been necessary to find meaning in life. Based on this concept, we explored older Chinese women immigrants'...

  7. Cross-cultural adaptation and Chinese students in Europe

    NARCIS (Netherlands)

    Broeder, Peter

    2014-01-01

    This contribution goes into the experiences of Chinese students studying at universities abroad. In the host societies they find themselves having to deal with major cultural confusion, which frustrates their education. Individualism and independence are characteristics strongly embedded in modern

  8. Nitric oxide does not mediate promotion of cellular potassium release by phenolphthalein in COS-7 cells.

    Science.gov (United States)

    Mason, Robert W; Hopp, Laszlo; Lloyd, John B

    2004-04-01

    1. It has been proposed that phenolphthalein exerts its laxative effect via an intracellular cascade that begins with the activation of nitric oxide synthase (NOS) and ends with an inhibition of NaCl and water reabsorption from the colon. Phenolphthalein also promotes the release of potassium from cells, but it is not known how this is related to its effect on sodium and water uptake. 2. An established in vitro system was used to examine the role of nitric oxide (NO) in phenolphthalein-induced release of (86)Rb(+) from COS-7 cells. 3. Sodium nitroprusside, an NOS-independent NO source, was unable to mimic the effects of phenolphthalein and N(G)-nitro-L-arginine methyl ester, an NOS inhibitor, was unable to block the effect of phenolphthalein. 4. It is concluded that NO generation is not required for phenolphthalein-stimulated potassium release. It is proposed that the effect of phenolphthalein on cellular potassium release is mechanistically distinct from the effect on NaCl and water uptake by colonocytes.

  9. J/ψ production in polarized and unpolarized ep collision and Sivers and cos 2φ asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Mukherjee, Asmita; Rajesh, Sangem [Indian Institute of Technology Bombay, Department of Physics, Mumbai (India)

    2017-12-15

    We calculate the Sivers and cos 2φ azimuthal asymmetries in J/ψ production in the polarized and unpolarized semi-inclusive ep collision, respectively, using the formalism based on the transverse momentum-dependent parton distributions (TMDs). The non-relativistic QCD-based color octet model is employed in calculating the J/ψ production rate. The Sivers asymmetry in this process directly probes the gluon Sivers function. The estimated Sivers asymmetry at z = 1 is negative, which is in good agreement with the COMPASS data. The effect of TMD evolution on the Sivers asymmetry is also investigated. The cos 2φ asymmetry is sizable and probes the linearly polarized gluon distribution in an unpolarized proton. (orig.)

  10. Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite Leishmania.

    Science.gov (United States)

    Gazanion, Élodie; Fernández-Prada, Christopher; Papadopoulou, Barbara; Leprohon, Philippe; Ouellette, Marc

    2016-05-24

    Innovative strategies are needed to accelerate the identification of antimicrobial drug targets and resistance mechanisms. Here we develop a sensitive method, which we term Cosmid Sequencing (or "Cos-Seq"), based on functional cloning coupled to next-generation sequencing. Cos-Seq identified >60 loci in the Leishmania genome that were enriched via drug selection with methotrexate and five major antileishmanials (antimony, miltefosine, paromomycin, amphotericin B, and pentamidine). Functional validation highlighted both known and previously unidentified drug targets and resistance genes, including novel roles for phosphatases in resistance to methotrexate and antimony, for ergosterol and phospholipid metabolism genes in resistance to miltefosine, and for hypothetical proteins in resistance to paromomycin, amphothericin B, and pentamidine. Several genes/loci were also found to confer resistance to two or more antileishmanials. This screening method will expedite the discovery of drug targets and resistance mechanisms and is easily adaptable to other microorganisms.

  11. Efficient propagation of archetype JC polyomavirus in COS-7 cells: evaluation of rearrangements within the NCCR structural organization after transfection.

    Science.gov (United States)

    Prezioso, Carla; Scribano, Daniela; Bellizzi, Anna; Anzivino, Elena; Rodio, Donatella Maria; Trancassini, Maria; Palamara, Anna Teresa; Pietropaolo, Valeria

    2017-12-01

    John Cunningham virus (JCPyV) is an ubiquitous human pathogen that causes disease in immunocompromised patients. The JCPyV genome is composed of an early region and a late region, which are physically separated by the non-coding control region (NCCR). The DNA sequence of the NCCR distinguishes two forms of JCPyV, the designated archetype and the prototype, which resulted from a rearrangement of the archetype sequence. To date, the cell culture systems for propagating JCPyV archetype have been very limited in their availability and robustness. Prior to this study, it was demonstrated that JCPyV archetype DNA replicates in COS-7 simian kidney cells expressing SV40 TAg and COS-7 cells expressing HIV-1 Tat. Based on these observations, the present study was conducted to reproduce an in vitro model in COS-7 cells transfected with the JCPyV archetype strain in order to study JCPyV DNA replication and analyze NCCR rearrangements during the viral life cycle. The efficiency of JCPyV replication was evaluated by quantitative PCR (Q-PCR) and by hemagglutination (HA) assay after transfection. In parallel, sequence analysis of JCPyV NCCR was performed. JCPyV efficiently replicated in kidney-derived COS-7 cells, as demonstrated by a progressive increase in viral load and virion particle production after transfection. The archetypal structure of NCCR was maintained during the viral cycle, but two characteristic point mutations were detected 28 days after transfection. This model is a useful tool for analyzing NCCR rearrangements during in vitro replication in cells that are sites of viral persistence, such as tubular epithelial cells of the kidney.

  12. A specific controlled ovarian stimulation (COS) protocol for fertility preservation in women with breast cancer undergoing neoadjuvant chemotherapy.

    Science.gov (United States)

    Cavagna, Felipe; Pontes, Anagloria; Cavagna, Mario; Dzik, Artur; Donadio, Nilka F; Portela, Rafael; Nagai, Michelle T; Gebrim, Luiz H

    2017-01-01

    The authors present a novel and specific controlled ovarian stimulation protocol for fertility preservation in women with estrogen-positive receptor breast cancer undergoing neoadjuvant chemotherapy. The protocol foresees random start ovarian stimulation and the use of letrozole associated to tamoxifen. Forty breast cancer patients were included in the study. COS was performed either with recombinant FSH or hMG. Concomitantly with COS, letrozole in a dose of 5 mg and tamoxifen in a dose of 20 mg were given orally on a daily basis. The trigger was performed with 0.2 mg of triptorelin, in the presence of follicles ≥ 19 mm. Oocyte retrieval was scheduled 35-36 hours after triptorelin injection. Our main outcome measures were the number of oocytes collected and number of oocytes vitrified, the length of ovarian stimulation, total dose of gonadotropins administered, and levels of estradiol on the day of the trigger. The mean age of patients was 30.43 ±4.25 years. Nineteen women commenced COS in the luteal phase, eleven in the early follicular phase and ten in the late follicular phase. The mean number of collected oocytes was 11.78 ±9.12 and the mean number of vitrified oocytes was 9.72 ±7.36. The mean duration of COS was 10.03 ±1.33 days. The mean estradiol concentrations on the triggering day was 623.10 ±441.27, and the mean dose of gonadotropins administered was 2540 ±713.10. The authors suggest that the protocol is efficient and may be a safe option for oocyte vitrification in these patients.

  13. Optics/Optical Diagnostics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optics/Optical Diagnostics Laboratory supports graduate instruction in optics, optical and laser diagnostics and electro-optics. The optics laboratory provides...

  14. Structure-Selective Cation Exchange in the Synthesis of Zincblende MnS and CoS Nanocrystals.

    Science.gov (United States)

    Fenton, Julie L; Schaak, Raymond E

    2017-06-01

    The ability to selectively form one crystal structure among several options in a polymorphic system is an important goal in solid-state synthesis. Nanocrystal cation exchange, which proceeds rapidly under mild conditions, can retain key structural features and yield otherwise inaccessible phases, but the extent to which crystal structure can be retained and therefore selectively targeted during such reactions has been limited. Here, we show that nanocrystals of digenite Cu 2-x S transform to zincblende MnS and CoS upon cation exchange. Zincblende MnS and CoS, which are metastable in bulk, retain both the tetrahedral cation coordination and cubic close packed anion sublattice of digenite Cu 2-x S. Comparison with wurtzite MnS and CoS, which have been accessed previously through analogous cation exchange of roxbyite Cu 2-x S, demonstrates the selective formation of the related zincblende vs. wurtzite polymorphs by cation exchange of structurally distinct templates. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Scoliosis Research Society

    Science.gov (United States)

    Scoliosis Research Society Close Menu Member Login Become a Member Home Find a Specialist | Calendar Contact | Donate ... a Member Find a Specialist Calendar Contact Donate Scoliosis Research Society Dedicated to the optimal care of ...

  16. American Society of Echocardiography

    Science.gov (United States)

    American Society of Echocardiography Join Ase Renew Member Portal Log In Membership Member Portal Log In Join ASE Renew Benefits Rates FASE – Fellow of the American Society of Echocardiography Member Referral Program FAQs Initiatives Advocacy Awards, Grants, ...

  17. Reclaiming Society Publishing

    Directory of Open Access Journals (Sweden)

    Philip E. Steinberg

    2015-07-01

    Full Text Available Learned societies have become aligned with commercial publishers, who have increasingly taken over the latter’s function as independent providers of scholarly information. Using the example of geographical societies, the advantages and disadvantages of this trend are examined. It is argued that in an era of digital publication, learned societies can offer leadership with a new model of open access that can guarantee high quality scholarly material whose publication costs are supported by society membership dues.

  18. Noise reduction methods applied to two-dimensional correlation spectroscopy (2D-COS) reveal complementary benefits of pre- and post-treatment.

    Science.gov (United States)

    Foist, Rod B; Schulze, H Georg; Ivanov, Andre; Turner, Robin F B

    2011-05-01

    Two-dimensional correlation spectroscopy (2D-COS) is a powerful spectral analysis technique widely used in many fields of spectroscopy because it can reveal spectral information in complex systems that is not readily evident in the original spectral data alone. However, noise may severely distort the information and thus limit the technique's usefulness. Consequently, noise reduction is often performed before implementing 2D-COS. In general, this is implemented using one-dimensional (1D) methods applied to the individual input spectra, but, because 2D-COS is based on sets of successive spectra and produces 2D outputs, there is also scope for the utilization of 2D noise-reduction methods. Furthermore, 2D noise reduction can be applied either to the original set of spectra before performing 2D-COS ("pretreatment") or on the 2D-COS output ("post-treatment"). Very little work has been done on post-treatment; hence, the relative advantages of these two approaches are unclear. In this work we compare the noise-reduction performance on 2D-COS of pretreatment and post-treatment using 1D (wavelets) and 2D algorithms (wavelets, matrix maximum entropy). The 2D methods generally outperformed the 1D method in pretreatment noise reduction. 2D post-treatment in some cases was superior to pretreatment and, unexpectedly, also provided correlation coefficient maps that were similar to 2D correlation spectroscopy maps but with apparent better contrast.

  19. In vitro studies of magnetically enhanced transfection in COS-7 cells

    International Nuclear Information System (INIS)

    Ang, D.; Tay, C.Y.; Tan, L.P.; Preiser, P.R.; Ramanujan, R.V.

    2011-01-01

    In the magnetically enhanced gene delivery technique, DNA complexed with polymer coated aggregated magnetic nanoparticles (AMNPs) is used for effecting transfection. The aim of this study is to examine the relationship between transfection efficiency and the physical characteristics of the polymer coated AMNPs. In vitro studies of transfection efficiency in COS-7 cells were carried out using pEGFP-N1 and pMIR-REPORT complexed polyethylenimine (PEI) coated iron oxide magnetic nanoparticles. PEI coated AMNPs (PEI-AMNPs) with average individual particle diameters in the range of 8 nm to 30 nm were studied and characterized by transmission electron microscopy, vibrating sample magnetometry, X-ray diffractometry, thermal gravimetric analysis and photon correlation spectroscopy methods. PEI-A8MNP and PEI-A30MNP yielded higher transfection efficiency compared to commercial polyMAG particles as well as PEI of equivalent molar ratio of nitrogen/phosphorous (N/P ratio). The transfection efficiency was related to the physical characteristics of the PEI-AMNPs and its complexes: transfection efficiency was strongly positively correlated with saturation magnetization (Ms) and susceptibility (χ), strongly negatively correlated with N/P ratio, moderately positively correlated to zeta potential and moderately negatively correlated to hydrodynamic diameter of the complex. PEI-A8MNP and PEI-A30MNP possessing higher Ms, χ, lower N/P ratio and smaller complex size exhibited higher transfection efficiency compared to PEI-A16MNP which have weaker magnetic properties, higher N/P ratio and larger complex size. We have demonstrated that optimization of the physical properties of PEI-AMNPs is needed to maximize transfection efficiency. - Research highlights: →The transfection efficiency in magnetically enhanced gene delivery was studied. →Transfection efficiency was strongly positively correlated to magnetic properties. →Transfection efficiency was strongly negatively correlated with

  20. Nicholson Medal Lecture: Scientists and Totalitarian Societies

    Science.gov (United States)

    Fang, Li-Zhi

    1997-04-01

    In order to call for support for his policy in China from the scientific community outside of China, Li Peng, China's premier today and at the time of Tiananmen massacre in 1989, published an editorial of ``Science" magazine (July 5, 1996) titled ``Why China needs science ... and partners." This editorial brought a serious problem, which is originally faced by scientists in a totalitarian society, upon the scientific community in free societies outside. It is well known that the current attitude of the Chinese government toward science is what it was during the years of Mao and the Soviet Union: science is limited to provide instruments useful to the rulers, but any degree of freedom, such as to challenge ideas, required by science to change the totalitarian regime itself, is suppressed. Thus, the problem facing us is: how to help your colleagues and promote science in a totalitarian society, without becoming a partner of the injustices of that regime.

  1. The Information Society

    Directory of Open Access Journals (Sweden)

    Hiranya Nath

    2017-03-01

    Full Text Available This article briefly discusses various definitions and concepts of the so-called information society. The term information society has been proposed to refer to the post-industrial society in which information plays a pivotal role. The definitions that have been proposed over the years highlight five underlying characterisations of an information society: technological, economic, sociological, spatial, and cultural. This article discusses those characteristics. While the emergence of an information society may be just a figment of one’s imagination, the concept could be a good organising principle to describe and analyse the changes of the past 50 years and of the future in the 21st century.

  2. Ecologizing industrialization in Chinese small towns

    NARCIS (Netherlands)

    Zhang, L.

    2002-01-01

    For historical reasons, any policies that attempt to address issues of Chinese farmers, agriculture and rural society are doomed to be facing dilemmas. One typical example is the question

  3. Competitiveness of chinese socialist market economy

    Directory of Open Access Journals (Sweden)

    Henry Ernesto Turner Barragán

    2015-08-01

    Full Text Available The article analyzes the dynamics held by the Chinese economy becomes, since it happened to be a communist to a capitalist economy and social market economy. Being in the latter, in which the country achieved high rates of economic growth, and improve their competitiveness pillars, generating higher growth prospects in the economy and the income of the society.

  4. Engendering social suffering: a Chinese diasporic community in northern Thailand.

    Science.gov (United States)

    Huang, Shu-Min

    2014-01-01

    This paper examines how reproducing Chineseness has become a source of social suffering through the case study of a group of Yunnan Chinese who escaped Chinese communist rules in the Mainland in 1949 or shortly after and settled in northern Thailand in the 1960s. As self-proclaimed carriers of traditional Chinese culture, they worked arduously to replicate whatever they considered 'authentic' Chinese through a narrow interpretation of the Confucian moral tenets in daily life. The (re)establishment of a patriarchal social order in Thailand - a society with a relatively high level of gender-equality, has inflicted tremendous pain and suffering among women and youth in this reified society. Ethnographic fieldwork, upon which this paper was based, was conducted in Maehong Village, Chiang Mai Province, between 2002 and 2007.

  5. Commercial Genetic Testing and Its Governance in Chinese Society

    Science.gov (United States)

    Sui, Suli; Sleeboom-Faulkner, Margaret

    2015-01-01

    This paper provides an empirical account of commercial genetic testing in China. Commercial predictive genetic testing has emerged and is developing rapidly in China, but there is no strict and effective governance. This raises a number of serious social and ethical issues as a consequence of the enormous potential market for such tests. The paper…

  6. Sexual revolution in China: implications for Chinese women and society.

    Science.gov (United States)

    Xiao, Zhiwen; Mehrotra, Purnima; Zimmerman, Rick

    2011-06-01

    China is undergoing rapid changes in sexual mores due to several reasons such as decreasing control of the state over private lives of individuals, globalization of its economy, and some policies initiated by the state. There is increased acceptance of premarital sex and extramarital sex in China, especially among youth. In historically conservative China, influenced by Confucian ideals of patriarchal dominance for centuries, the sexual freedom currently enjoyed by many is unprecedented. This has impacted women's status and sexual lives in several positive ways such as increasing freedom of sexual expression, control over their bodies, sexual choices, and increasing equality with men in all spheres of life. However several negative consequences such as a rise in STD/HIV prevalence, commercial sex, and divorce rates have also been attributed to the ongoing sexual revolution in China. Recommendations combating these and suggestions for directions in future research are discussed.

  7. Asian Creativity, Chapter One: Creativity across Three Chinese Societies

    Science.gov (United States)

    Wu, Jing-Jyi; Albanese, Dale

    2010-01-01

    This commentary looks at the contributions and future research implications of the four articles in this Special Issue of "Thinking Skills and Creativity" to the fields of creativity and creativity education, both in culture-specific and culture-general terms. The articles included in this Special Issue draw attention to issues of…

  8. Filial piety, authoritarian moralism, and cognitive conservatism in Chinese societies.

    Science.gov (United States)

    Ho, D Y

    1994-08-01

    In the present study, I examined the role of Confucian filial piety in relation to parental attitudes, the function of personality, and social cognition, using data assembled from 11 samples of adults and students in Hong Kong and Taiwan. Results showed that (a) filial attitudes tend to be moderately associated with parental attitudes and child training that emphasize obedience and indebtedness to one's parents, impulse control, and proper conduct; (b) people endorsing traditional filial and/or child-training attitudes tend to be poorer in verbal fluency, to adopt a passive, uncritical, and uncreative orientation toward learning, to hold fatalistic, superstitious, and stereotypic beliefs, and to be authoritarian, dogmatic, and conformist; and (c) parents' attitudes rooted in filial piety tend to result in high rigidity and low cognitive complexity in their children. The results support the contention that filial piety underlies both authoritarian moralism and cognitive conservatism.

  9. Journal of Chinese Society of Astronautics (Selected Articles),

    Science.gov (United States)

    1987-04-06

    simulated axial oscillation of flexible j 3 -Z 3 snq’oqn ig i. The flexible r’nnecon heal connects * aptiely with the end ring and the lower flat plate...n n tiol - ’ 1 hch z., -ind Z, ’-tr’e i,iaf t w iosly smualler ,2 , ,er >1 : ’-le Thiereore, we take the two solution sets of s . , ’,;’,q r-sps ti...axes . The reason for this is that the intersection line of R, and R,_,. is located on R,_, on the one hand , arid,, therefore, crosses the Z1-1 axis

  10. Journal of the Chinese Society of Astronautics (Selected Articles),

    Science.gov (United States)

    1983-07-01

    many small disturbances, then the error model may be written as f(3) According to the Central Limit Theorem , normal distribution N(m, a) must be...intuitively from Figure 1. fl. ± * a PCP ; P-, Pz P* P Figure 1 Figure 2 -ra iator s note: In- - forei gn text. Fence, we should use "high negative

  11. Optical and electrical properties of chemical bath deposited cobalt sulphide thin films

    Energy Technology Data Exchange (ETDEWEB)

    Govindasamy, Geetha [R& D Centre, Bharathiar University, Coimbatore (India); Murugasen, Priya, E-mail: priyamurugasen15@gmail.com [Department of Physics, Saveetha Engineering, Chennai, Tamil Nadu (India); Sagadevan, Suresh [Department of Physics, AMET University, Chennai, Tamil Nadu (India)

    2017-01-15

    Cobalt sulphide (CoS) thin films were synthesized using the Chemical Bath Deposition (CBD) technique. X-ray diffraction (XRD) analysis was used to study the structure and the crystallite size of CoS thin film. Scanning Electron Microscope (SEM) studies reveal the surface morphology of these films. The optical properties of the CoS thin films were determined using UV-Visible absorption spectrum. The optical band gap of the thin films was found to be 1.6 eV. Optical constants such as the refractive index, the extinction coefficient and the electric susceptibility were determined. The dielectric studies were carried out at different frequencies and at different temperatures for the prepared CoS thin films. In addition, the plasma energy of the valence electron, Penn gap or average energy gap, the Fermi energy and electronic polarizability of the thin films were determined. The AC electrical conductivity measurement was also carried out for the thin films. The activation energy was determined by using DC electrical conductivity measurement. (author)

  12. Investigating Chinese Migrants’ Information-Seeking Patterns in Canada: Media Selection and Language Preference

    Directory of Open Access Journals (Sweden)

    Yuping Mao

    2015-12-01

    Full Text Available Taking a quantitative approach, this research surveyed Chinese migrants in Canada regarding channels they rely on to seek various information. This research also investigates how Chinese migrants’ preferences of channels correlate with their intercultural sensitivity level. Chinese migrants prefer Chinese newspapers and websites for government/policy information and life information rather than English newspapers and websites. However, they use English newspapers and websites more frequently for job and career development information. Overall, English television and radio are more frequently used by Chinese migrants than Chinese television and radio broadcasts. The intercultural sensitivity levels of Chinese migrants have a positive correlation with their frequencies of using English information resources, including government websites, English newspapers, English non-government websites, government officers, personal non-Chinese social networks, and English television and radio. Findings of this research suggest that Chinese ethnic media play an important role in Chinese migrants’ information-seeking behaviours and patterns in Canada. On one hand, government and other organizations can reach the Chinese migrant community through information diffusion in Chinese ethnic media. On the other hand, Chinese migrants should make an active effort to improve their English proficiency and intercultural communication sensitivity to better integrate themselves into the Canadian society. A more balanced approach of seeking information from English and Chinese media sources could be more beneficial for Chinese migrants.

  13. Indian Vacuum Society: The Indian Vacuum Society

    Science.gov (United States)

    Saha, T. K.

    2008-03-01

    The Indian Vacuum Society (IVS) was established in 1970. It has over 800 members including many from Industry and R & D Institutions spread throughout India. The society has an active chapter at Kolkata. The society was formed with the main aim to promote, encourage and develop the growth of Vacuum Science, Techniques and Applications in India. In order to achieve this aim it has conducted a number of short term courses at graduate and technician levels on vacuum science and technology on topics ranging from low vacuum to ultrahigh vacuum So far it has conducted 39 such courses at different parts of the country and imparted training to more than 1200 persons in the field. Some of these courses were in-plant training courses conducted on the premises of the establishment and designed to take care of the special needs of the establishment. IVS also regularly conducts national and international seminars and symposia on vacuum science and technology with special emphasis on some theme related to applications of vacuum. A large number of delegates from all over India take part in the deliberations of such seminars and symposia and present their work. IVS also arranges technical visits to different industries and research institutes. The society also helped in the UNESCO sponsored post-graduate level courses in vacuum science, technology and applications conducted by Mumbai University. The society has also designed a certificate and diploma course for graduate level students studying vacuum science and technology and has submitted a syllabus to the academic council of the University of Mumbai for their approval, we hope that some colleges affiliated to the university will start this course from the coming academic year. IVS extended its support in standardizing many of the vacuum instruments and played a vital role in helping to set up a Regional Testing Centre along with BARC. As part of the development of vacuum education, the society arranges the participation of

  14. Civil Society and Governance

    DEFF Research Database (Denmark)

    Hulgård, Lars

    An illustration of how important the relationship is between civil society anbd governance. A short historic journey with four snapshots of times and situations that have provided interesting evidence about the connection between civil society and governance. My goal for the short historic journey...... is to make clear and hopefully even verify that providing knowledge about the impact of civil society and citizens’ participation on governance is one of the most urgent research tasks in the current period of time....

  15. American Society of Nephrology

    Science.gov (United States)

    ... Society of Nephrology (CJASN) Kidney News Kidney News Online Kidney Week Abstracts In The Loop Request Missing Publication Advertising Opportunities Advocacy and public policy Legislative Action Center ...

  16. Optical high-performance computing: introduction to the JOSA A and Applied Optics feature.

    Science.gov (United States)

    Caulfield, H John; Dolev, Shlomi; Green, William M J

    2009-08-01

    The feature issues in both Applied Optics and the Journal of the Optical Society of America A focus on topics of immediate relevance to the community working in the area of optical high-performance computing.

  17. Measures and the Current Situation of the Aging Society in China

    OpenAIRE

    周, 金蘭; Zhou. Jinlan

    2015-01-01

    In China, the proportion of the elderly population over 60 years-old is more than 10% in 2000, and the Chinese have become an aging society. However, there are several problems of this aging society, for example, rapid aging speed, becoming old before rich, and different welfare situation in different provinces. Progress carried out by the Chinese government has done much to solve such problems Due to the increase of the elderly population, the related burdens also raises, such as the economi...

  18. High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms.

    Science.gov (United States)

    Fernandez-Prada, Christopher; Sharma, Mansi; Plourde, Marie; Bresson, Eva; Roy, Gaétan; Leprohon, Philippe; Ouellette, Marc

    2018-03-16

    Increasing drug resistance towards first line antimony-derived compounds has forced the introduction of novel therapies in leishmaniasis endemic areas including amphotericin B and miltefosine. However, their use is threatened by the emergence and spread of drug-resistant strains. In order to discover stage-dependent resistance genes, we have adapted the Cos-Seq approach through the introduction of macrophage infections in the pipeline. A L. infantum intracellular amastigote population complemented with a L. infantum cosmid library was submitted to increasing concentrations of miltefosine, amphotericin B and pentavalent antimonials in experimental infections of THP-1 cells. For each step of selection, amastigotes were extracted and cosmids were isolated and submitted to next-generation sequencing, followed by subsequent gene-enrichment analyses. Cos-Seq screen in amastigotes revealed four highly enriched loci for antimony, five for miltefosine and one for amphotericin B. Of these, a total of seven cosmids were recovered and tested for resistance in both promastigotes and amastigotes. Candidate genes within the pinpointed genomic regions were validated using single gene overexpression in wild-type parasites and/or gene disruption by means of a CRISPR-Cas9-based approach. This led to the identification and validation of a stage-independent antimony-resistance gene (LinJ.06.1010) coding for a putative leucine rich repeat protein and a novel amastigote-specific miltefosine-resistance gene (LinJ.32.0050) coding for a member of the SEC13 family of WD-repeat proteins. This study further reinforces the power of Cos-Seq approach to discover novel drug-resistance genes, some of which are life-stages specific. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  19. Unknown plant de-construction hazard -- Toxic COS and CS2 gas from torch cutting of pipe

    International Nuclear Information System (INIS)

    Martin, H.L.; Nutt, A.W.; Myers, B.L.; Hightower, J.O.

    1994-01-01

    An employee exhibited signs of illness after apparently inhaling fumes generated from a pipe that had been cut with a cutting torch. Identification and quantification of the hazardous air emission for reduction of risk via the Department of Energy Class B Investigation are described in this case study. The old hydrogen sulfide gas flare pipe in the heavy water plant of the Savannah River Site has been abandoned with one end open to atmosphere for almost twenty years. The pipe was being removed and cut into sections for disposal during an asbestos abatement project. It contained ash like corrosion deposits that smolder after torch cutting. Investigation revealed that burning of carbon and sulfur in the oxygen deficient atmosphere in the ash generated carbonyl sulfide (COS) and carbon disulfide (CS 2 ) gas, which vented when the pipe was moved by the injured construction rigger. This is believed to be the first well documented exposure and response of a human to high concentration COS gas. Sulfur dioxide (SO 2 ) gas is also generated during the cutting. SO 2 is almost impossible to inhale and has apparently prevented a similar injury during the cutting. SO 2 is almost impossible to inhale and has apparently prevented a similar injury during the many years of US and Canadian heavy water plant de-construction experience. Immediate water quench of the smoldering ash after each cut has eliminated the hazard of residual COS and CS 2 gas. This previously unrecognized industrial hazard may be encountered by other chemical and petroleum industries during torch cutting of pipes that contain similar deposits of iron oxide, iron sulfate, sulfur and carbon

  20. Rectification of the water permeability in COS-7 cells at 22, 10 and 0°C.

    Directory of Open Access Journals (Sweden)

    Diana B Peckys

    Full Text Available The osmotic and permeability parameters of a cell membrane are essential physico-chemical properties of a cell and particularly important with respect to cell volume changes and the regulation thereof. Here, we report the hydraulic conductivity, L(p, the non-osmotic volume, V(b, and the Arrhenius activation energy, E(a, of mammalian COS-7 cells. The ratio of V(b to the isotonic cell volume, V(c iso, was 0.29. E(a, the activation energy required for the permeation of water through the cell membrane, was 10,700, and 12,000 cal/mol under hyper- and hypotonic conditions, respectively. Average values for L(p were calculated from swell/shrink curves by using an integrated equation for L(p. The curves represented the volume changes of 358 individually measured cells, placed into solutions of nonpermeating solutes of 157 or 602 mOsm/kg (at 0, 10 or 22°C and imaged over time. L(p estimates for all six combinations of osmolality and temperature were calculated, resulting in values of 0.11, 0.21, and 0.10 µm/min/atm for exosmotic flow and 0.79, 1.73 and 1.87 µm/min/atm for endosmotic flow (at 0, 10 and 22°C, respectively. The unexpected finding of several fold higher L(p values for endosmotic flow indicates highly asymmetric membrane permeability for water in COS-7. This phenomenon is known as rectification and has mainly been reported for plant cell, but only rarely for animal cells. Although the mechanism underlying the strong rectification found in COS-7 cells is yet unknown, it is a phenomenon of biological interest and has important practical consequences, for instance, in the development of optimal cryopreservation.

  1. TRADITIONAL CHINESE HERBAL MEDICINE

    NARCIS (Netherlands)

    ZHU, YP; WOERDENBAG, HJ

    1995-01-01

    Herbal medicine, acupuncture and moxibustion, and massage and the three major constituent parts of traditional Chinese medicine. Although acupuncture is well known in many Western countries, Chinese herbal medicine, the mos important part of traditional Chinese medicine, is less well known in the

  2. Chinese restaurant syndrome

    Directory of Open Access Journals (Sweden)

    Balachandran C

    1991-01-01

    Full Text Available A 24-year-old Chinese student with history of recurrent attacks of flushing with burning and dryness of face of 4 years duration showed exacerbation of the symptoms after oral provocation with 1 mg of Chinese salt. Patient was treated with 50 mg pyridoxine daily and restriction of the Chinese salt in diet with moderate improvement.

  3. Towards core outcome set (COS) development: a follow-up descriptive survey of outcomes in Cochrane reviews.

    Science.gov (United States)

    Wuytack, Francesca; Smith, Valerie; Clarke, Mike; Williamson, Paula; Gargon, Elizabeth

    2015-05-19

    A core outcome set (COS) can address problems of outcome heterogeneity and outcome reporting bias in trials and systematic reviews, including Cochrane reviews, helping to reduce waste. One of the aims of the international Core Outcome Measures in Effectiveness Trials (COMET) Initiative is to link the development and use of COS with the outcomes specified and reported in Cochrane reviews, including the outcomes listed in the summary of findings (SoF) tables. As part of this work, an earlier exploratory survey of the outcomes of newly published 2007 and 2011 Cochrane reviews was performed. This survey examined the use of COS, the variety of specified outcomes, and outcome reporting in Cochrane reviews by Cochrane Review Group (CRG). To examine changes over time and to explore outcomes that were repeatedly specified over time in Cochrane reviews by CRG, we conducted a follow-up survey of outcomes in 2013 Cochrane reviews. A descriptive survey of outcomes in Cochrane reviews that were first published in 2013. Outcomes specified in the methods sections and reported in the results section of the Cochrane reviews were examined by CRG. We also explored the uptake of SoF tables, the number of outcomes included in these, and the quality of the evidence for the outcomes. Across the 50 CRGs, 375 Cochrane reviews that included at least one study specified a total of 3142 outcomes. Of these outcomes, 32 % (1008) were not reported in the results section of these reviews. For 23 % (233) of these non-reported outcomes, we did not find any reason in the text of the review for this non-report. Fifty-seven percent (216/375) of reviews included a SoF table. The proportion of specified outcomes that were reported in Cochrane reviews had increased in 2013 (68 %) compared to 2007 (61 %) and 2011 (65 %). Importantly, 2013 Cochrane reviews that did not report specified outcomes were twice as likely to provide an explanation for why the outcome was not reported. There has been an increased

  4. ‘But the Dutch would call it exploitation’. : Crimmigration and the moral economy of the Chinese catering industry in the Netherlands

    NARCIS (Netherlands)

    J.W. Hiah (Jing); R.H.J.M. Staring (Richard)

    2016-01-01

    markdownabstractBased on qualitative research into the Chinese catering industry in the Netherlands, this article describes labour relations between Chinese employers and their (undocumented) employees against the background of a society in which criminal, administrative, and immigration law

  5. Peptide Optical waveguides.

    Science.gov (United States)

    Handelman, Amir; Apter, Boris; Shostak, Tamar; Rosenman, Gil

    2017-02-01

    Small-scale optical devices, designed and fabricated onto one dielectric substrate, create integrated optical chip like their microelectronic analogues. These photonic circuits, based on diverse physical phenomena such as light-matter interaction, propagation of electromagnetic waves in a thin dielectric material, nonlinear and electro-optical effects, allow transmission, distribution, modulation, and processing of optical signals in optical communication systems, chemical and biological sensors, and more. The key component of these optical circuits providing both optical processing and photonic interconnections is light waveguides. Optical confinement and transmitting of the optical waves inside the waveguide material are possible due to the higher refractive index of the waveguides in comparison with their surroundings. In this work, we propose a novel field of bionanophotonics based on a new concept of optical waveguiding in synthetic elongated peptide nanostructures composed of ordered peptide dipole biomolecules. New technology of controllable deposition of peptide optical waveguiding structures by nanofountain pen technique is developed. Experimental studies of refractive index, optical transparency, and linear and nonlinear waveguiding in out-of-plane and in-plane diphenylalanine peptide nanotubes have been conducted. Optical waveguiding phenomena in peptide structures are simulated by the finite difference time domain method. The advantages of this new class of bio-optical waveguides are high refractive index contrast, wide spectral range of optical transparency, large optical nonlinearity, and electro-optical effect, making them promising for new applications in integrated multifunctional photonic circuits. Copyright © 2016 European Peptide Society and John Wiley & Sons, Ltd. Copyright © 2016 European Peptide Society and John Wiley & Sons, Ltd.

  6. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.

    Science.gov (United States)

    Cobb, Melanie M; Austin, Daniel C; Sack, Jon T; Trimmer, James S

    2015-12-04

    The plasma membrane (PM) comprises distinct subcellular domains with diverse functions that need to be dynamically coordinated with intracellular events, one of the most impactful being mitosis. The Kv2.1 voltage-gated potassium channel is conditionally localized to large PM clusters that represent specialized PM:endoplasmic reticulum membrane contact sites (PM:ER MCS), and overexpression of Kv2.1 induces more exuberant PM:ER MCS in neurons and in certain heterologous cell types. Localization of Kv2.1 at these contact sites is dynamically regulated by changes in phosphorylation at one or more sites located on its large cytoplasmic C terminus. Here, we show that Kv2.1 expressed in COS-1 cells undergoes dramatic cell cycle-dependent changes in its PM localization, having diffuse localization in interphase cells, and robust clustering during M phase. The mitosis-specific clusters of Kv2.1 are localized to PM:ER MCS, and M phase clustering of Kv2.1 induces more extensive PM:ER MCS. These cell cycle-dependent changes in Kv2.1 localization and the induction of PM:ER MCS are accompanied by increased mitotic Kv2.1 phosphorylation at several C-terminal phosphorylation sites. Phosphorylation of exogenously expressed Kv2.1 is significantly increased upon metaphase arrest in COS-1 and CHO cells, and in a pancreatic β cell line that express endogenous Kv2.1. The M phase clustering of Kv2.1 at PM:ER MCS in COS-1 cells requires the same C-terminal targeting motif needed for conditional Kv2.1 clustering in neurons. The cell cycle-dependent changes in localization and phosphorylation of Kv2.1 were not accompanied by changes in the electrophysiological properties of Kv2.1 expressed in CHO cells. Together, these results provide novel insights into the cell cycle-dependent changes in PM protein localization and phosphorylation. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Refractions of Civil Society

    DEFF Research Database (Denmark)

    Kuzmanovic, Daniella

    The thesis investigates various perceptions of civil society among civic activists in Turkey, and how these perceptions are produced and shaped. The thesis is an anthropological contribution to studies of civil society in general, as well as to studies on political culture in Turkey....

  8. World Society and Globalisation

    Science.gov (United States)

    Wittmann, Veronika

    2014-01-01

    Purpose: The purpose of this paper is to illustrate discourses on globalisation and world society and to disclose the commonalities and differences of both scientific debates. In particular, it draws attention to theoretical concepts of globalisation and world society. This is considered fruitful for comprehending the complex mechanisms of…

  9. Transformation of Neolithic Societies

    DEFF Research Database (Denmark)

    Iversen, Rune

    and prepared the way for the appearance of Bronze Age societies. The great era of megalithic architecture came to an end as the production and exchange of gold, copper and bronze objects became the driving force in the development of Copper and Bronze Age societies. This development also had a great influence...

  10. Producing Civil Society

    DEFF Research Database (Denmark)

    Feldt, Liv Egholm; Hein Jessen, Mathias

    ’ and as such dominates our way of thinking about civil society. Yet, this view hinders the understanding of how civil society is not a pre-existing or given sphere, but a sphere which is constantly produced both discursively, conceptually and practically. Through two examples; 1,the case of philanthropy in the beginning...

  11. Society-ethics-risk

    International Nuclear Information System (INIS)

    Ruh, H.; Seiler, H.

    1993-01-01

    The aim of the workshops which was reported in this volume, was the interpretation and evaluation of catastrophic risks for society in an interdisciplinary dialogue between representation of society, ethics, as well as natural science and technology. (author) figs., tabs., refs

  12. The Tranquebarian Society

    DEFF Research Database (Denmark)

    Jensen, Niklas Thode

    2015-01-01

    of this development was the establishment of the Tranquebarian Society, the third learned society east of the Cape of Good Hope. The article examines the unique assemblage of scientific networks, people, instruments, institutions, and ideas of local and global origin that converged in Tranquebar, and it investigates...

  13. Chitin Oligosaccharide (COS) Reduces Antibiotics Dose and Prevents Antibiotics-Caused Side Effects in Adolescent Idiopathic Scoliosis (AIS) Patients with Spinal Fusion Surgery.

    Science.gov (United States)

    Qu, Yang; Xu, Jinyu; Zhou, Haohan; Dong, Rongpeng; Kang, Mingyang; Zhao, Jianwu

    2017-03-14

    Antibiotics are always considered for surgical site infection (SSI) in adolescent idiopathic scoliosis (AIS) surgery. However, the use of antibiotics often causes the antibiotic resistance of pathogens and side effects. Thus, it is necessary to explore natural products as drug candidates. Chitin Oligosaccharide (COS) has anti-inflammation and anti-bacteria functions. The effects of COS on surgical infection in AIS surgery were investigated. A total of 312 AIS patients were evenly and randomly assigned into control group (CG, each patient took one-gram alternative Azithromycin/Erythromycin/Cloxacillin/Aztreonam/Ceftazidime or combined daily), experiment group (EG, each patient took 20 mg COS and half-dose antibiotics daily), and placebo group (PG, each patient took 20 mg placebo and half-dose antibiotics daily). The average follow-up was one month, and infection severity and side effects were analyzed. The effects of COS on isolated pathogens were analyzed. SSI rates were 2%, 3% and 8% for spine wounds and 1%, 2% and 7% for iliac wound in CG, EG and PG ( p antibiotics ( p antibiotics dose and antibiotics-caused side effects in AIS patients with spinal fusion surgery by improving antioxidant and anti-inflammatory activities. COS should be developed as potential adjuvant for antibiotics therapies.

  14. Gridded anthropogenic emissions inventory and atmospheric transport of carbonyl sulfide in the U.S.: U.S. Anthropogenic COS Source and Transport

    Energy Technology Data Exchange (ETDEWEB)

    Zumkehr, Andrew [Sierra Nevada Research Institute, University of California, Merced California USA; Hilton, Timothy W. [Sierra Nevada Research Institute, University of California, Merced California USA; Whelan, Mary [Sierra Nevada Research Institute, University of California, Merced California USA; Smith, Steve [Joint Global Change Research Institute, PNNL, College Park Maryland USA; Campbell, J. Elliott [Sierra Nevada Research Institute, University of California, Merced California USA

    2017-02-21

    Carbonyl sulfide (COS or OCS), the most abundant sulfur containing gas in the troposphere, has recently emerged as a potentially important atmospheric tracer for the carbon cycle. Atmospheric inverse modeling studies may be able to use existing tower, airborne, and satellite observations of COS to infer information about photosynthesis. However, such analysis relies on gridded anthropogenic COS source estimates that are largely based on industry activity data from over three decades ago. Here we use updated emission factor data and industry activity data to develop a gridded inventory with a 0.1 degree resolution for the U.S. domain. The inventory includes the primary anthropogenic COS sources including direct emissions from the coal and aluminum industries as well as indirect sources from industrial carbon disulfide emissions. Compared to the previously published inventory, we found that the total anthropogenic source (direct and indirect) is 47% smaller. Using this new gridded inventory to drive the STEM/WRF atmospheric transport model, we found that the anthropogenic contribution to COS variation in the troposphere is small relative to the biosphere influence, which is encouraging of carbon cycle applications in this region. Additional anthropogenic sectors with highly uncertain emission factors require further field measurements.

  15. Well-dispersed CoS nanoparticles on a functionalized graphene nanosheet surface: a counter electrode of dye-sensitized solar cells.

    Science.gov (United States)

    Miao, Xiaohuan; Pan, Kai; Wang, Guofeng; Liao, Yongping; Wang, Lei; Zhou, Wei; Jiang, Baojiang; Pan, Qingjiang; Tian, Guohui

    2014-01-07

    With a facile electrophoretic deposition and chemical bath process, CoS nanoparticles have been uniformly dispersed on the surface of the functionalized graphene nanosheets (FGNS). The composite was employed as a counter electrode of dye-sensitized solar cells (DSSCs), which yielded a power conversion efficiency of 5.54 %. It is found that this efficiency is higher than those of DSSCs based on the non-uniform CoS nanoparticles on FGNS (4.45 %) and built on the naked CoS nanoparticles (4.79 %). The achieved efficiency of our cost-effective DSSC is also comparable to that of noble metal Pt-based DSSC (5.90 %). Our studies have revealed that both the exceptional electrical conductivity of the FGNS and the excellent catalytic activity of the CoS nanoparticles improve the conversion efficiency of the uniformly FGNS-CoS composite counter electrode. The electrochemical impedance spectra, cyclic voltammetry, and Tafel polarization have evidenced the best catalytic activity and the fastest electron transport. Additionally, the dispersion condition of CoS nanoparticles on FGNS plays an important role for catalytic reduction of I3 (-) . Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. ER reorganization is remarkably induced in COS-7 cells accumulating transmembrane protein receptors not competent for export from the endoplasmic reticulum.

    Science.gov (United States)

    D'Agostino, Massimo; Crespi, Arianna; Polishchuk, Elena; Generoso, Serena; Martire, Gianluca; Colombo, Sara Francesca; Bonatti, Stefano

    2014-11-01

    The newly synthesized mutant L501fsX533 Frizzled-4 form and the alpha3beta4 nicotinic acetylcholine receptor expressed in the absence of nicotine accumulate in the endoplasmic reticulum of COS-7 cells and induce the formation of large areas of smooth and highly convoluted cisternae. This results in a generalized block of the transport to the Golgi complex of newly synthesized proteins. Intriguingly, both effects happen peculiarly in COS-7 cells; HeLa, Huh-7, and HEK293 cells expressing the two receptors at similar level than COS-7 cells show normal ER and normal transport toward the plasma membrane. These results question the conclusion that a dominant-negative mechanism would explain the dominance of the mutant L501fsX533 Fz4 allele in the transmission of a form of Familial exudative vitreoretinopathy. Moreover, they indicate that the coordination of endoplasmic reticulum homeostasis in COS-7 cells is particularly error prone. This finding suggests that COS-7 cells may be extremely useful to study the molecular mechanisms regulating endoplasmic reticulum size and architecture.

  17. COSWEETTM: A New Process to Reach Very High COS Specification on Natural Gas Treatment Combined with Selective H2S Removal

    Directory of Open Access Journals (Sweden)

    Magné-Drisch Julia

    2016-05-01

    Full Text Available COSWEETTM, developed for the treatment of COS containing natural gases, is based on a combination of deacidification with any alkanolamine solution and COS hydrolysis on a metal oxide based catalyst. Nearly complete COS conversion is reached, even at a relatively low operating temperature. Coupled with a classical sweetening unit, in which an adapted alkanolamine solvent is used in order to optimise the removal of H2S, CO2, as well as the H2S/CO2 selectivity, the high catalyst activity and the original integration of the scheme secure the COS removal at minimum extra cost. Benefits on capital and operating expenditures of the plant result both from the reduction of the absorption column and solvent flow rate and from the quality of the acid gas which has positive consequences on the design of the sulfur recovery facilities units, including Claus unit. This paper presents the complete development process approach and the results obtained on COS conversion, the model and simulation tool as well as a case study showing the advantages of coupling COSWEETTM to amine based solvent.

  18. Effects of Astragalus polysaccharides (APS) and chitooligosaccharides (COS) on growth, immune response and disease resistance of juvenile largemouth bass, Micropterus salmoides.

    Science.gov (United States)

    Lin, Shi-Mei; Jiang, Yu; Chen, Yong-Jun; Luo, Li; Doolgindachbaporn, Sompong; Yuangsoi, Bundit

    2017-11-01

    The effects of oral administration of Astragalus polysaccharides (APS) and chitooligosaccharides (COS), single or combined, on the growth performance, immunity and disease resistance of M. salmoides were investigated. Largemouth bass juvenile were divided into 4 groups and each group was fed with diets supplemented with or without immunostimulant for 8 weeks. After 8 weeks of feeding trial, five fish per tank were sampled for immunity determination, ten fish per tank were challenged by A. hydrophila. The results showed that the largemouth bass fed with two immunostimulants alone or in combination significantly enhanced the final weight and specific growth rate (SGR), decreased feed conversion ratio (FCR) (P APS. In addition, both COS and APS upregulated respiratory burst activity (RBA), phagocytic activity (PA), lysozyme activity and superoxide dismutase (SOD) activity. Meanwhile, COS also exhibited a increase in total leukocyte count, nitric oxide (NO) content and inducible nitric oxide synthase (iNOS) activity compared to the control. When challenged with A. hydrophila, the mortality of groups fed with COS and/or APS was lower than the control (P APS and COS had a synergistic effect on lysozme activity, iNOS activity, NO content and disease resistance of fish (P < 0.05). Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Sexual abuse trauma among Chinese survivors.

    Science.gov (United States)

    Tsun-Yin, E L

    1998-10-01

    As an initial effort to examine Chinese sexual abuse trauma in relation to the cultural construction of sexual victimization of women, this study applies Finkelhor and Browne's (1985) traumagenic dynamics model to examine post-abuse trauma among Chinese child and adolescent survivors in Taiwan. In analyzing sexual abuse trauma in the context of Chinese patriarchal familialism and cultural fetish for female chastity, this study attempts to explore cultural constructional process of sexual abuse in Chinese society. This study conducted in-depth interviews with 19 survivors of, and three social workers on, sexual abuse in Taiwan. These interviews were guided by a semi-structured questionnaire on sexual abuse incidents and post-abuse responses/concerns, and had generated a total of 84 pages of written reports, which serve as the text-data for the analysis. This study identifies sexual stigmatization and senses of disempowerment and betrayal as the most pervasive trauma complex among Chinese sexual abuse survivors in Taiwan. This study found that, in addition to lowering self-esteem, sexual stigmatization results in polarized sexuality among adolescent survivors, as manifested in aversion to and preoccupation with sexuality. The abuse-induced disempowerment is manifested in the survivors' fear for personal safety and heightened sense of vulnerability to re-victimization. The sense of betrayal results in interpersonal difficulties as manifested in self-imposed isolation from others and/or suspicious attitudes toward others, which further impair the survivor's efficacy in meeting her abuse-induced clinging need. Overall, this study observes similar traumatic symptoms between Chinese survivors and their American counterparts as documented in the literature. Nevertheless, this study observes the sexual stigmatization represents the most prevailing post-abuse trauma among Chinese sexual abuse survivors, and reflects the patriarchal fetish for female chastity in the Chinese

  20. Climate and Ancient Societies

    DEFF Research Database (Denmark)

    Climate, and human responses to it, have a strongly interconnected relationship. This when climate change occurs, the result of either natural or human causes, societies should react and adapt to these. But do they? If so, what is the nature of that change, and are the responses positive...... or negative for the long-term survival of social groups? In this volume, scholars from diverse disciplines including archaeology, geology and climate sciences explore scientific and material evidence for climate changes in the past, their causes, their effects on ancient societies and how those societies...

  1. Information society studies

    CERN Document Server

    Duff, Alistair S

    2013-01-01

    We are often told that we are ""living in an information society"" or that we are ""information workers."" But what exactly do these claims mean, and how might they be verified? In this important methodological study, Alistair S. Duff cuts through the rhetoric to get to the bottom of the ""information society thesis."" Wide-ranging in coverage, this study will be of interest to scholars in information science, communication and media studies and social theory. It is a key text for the newly-unified specialism of information society studies, and an indispensable guide to the future of this disc

  2. First genetic linkage map of Taraxacum koksaghyz Rodin based on AFLP, SSR, COS and EST-SSR markers.

    Science.gov (United States)

    Arias, Marina; Hernandez, Monica; Remondegui, Naroa; Huvenaars, Koen; van Dijk, Peter; Ritter, Enrique

    2016-08-04

    Taraxacum koksaghyz Rodin (TKS) has been studied in many occasions as a possible alternative source for natural rubber production of good quality and for inulin production. Some tire companies are already testing TKS tire prototypes. There are also many investigations on the production of bio-fuels from inulin and inulin applications for health improvement and in the food industry. A limited amount of genomic resources exist for TKS and particularly no genetic linkage map is available in this species. We have constructed the first TKS genetic linkage map based on AFLP, COS, SSR and EST-SSR markers. The integrated linkage map with eight linkage groups (LG), representing the eight chromosomes of Russian dandelion, has 185 individual AFLP markers from parent 1, 188 individual AFLP markers from parent 2, 75 common AFLP markers and 6 COS, 1 SSR and 63 EST-SSR loci. Blasting the EST-SSR sequences against known sequences from lettuce allowed a partial alignment of our TKS map with a lettuce map. Blast searches against plant gene databases revealed some homologies with useful genes for downstream applications in the future.

  3. Antagonism of serotonin receptor 1B decreases viability and promotes apoptosis in the COS canine osteosarcoma cell line.

    Science.gov (United States)

    Viall, A K; Goodall, C P; Stang, B; Marley, K; Chappell, P E; Bracha, S

    2016-06-01

    Serotonin receptor 1B (5HTR1B) traditionally exhibits anti-proliferative activity in osteoblasts. We examined the expression and function of 5HTR1B in the COS canine osteosarcoma cell line and normal canine osteoblasts. Equal levels of 5HTR1B gene and protein expression were found between normal and malignant osteoblasts. Treatment with serotonin enhanced viability of osteosarcoma cells but not normal osteoblasts. Challenge with the 5HTR1B agonist anpirtoline caused no change in cell viability. Rather incubation with the specific receptor antagonist SB224289 caused reduction in osteoblast viability, with this effect more substantial in osteosarcoma cells. Investigation of this inhibitory activity showed 5HTR1B antagonism induces apoptosis in malignant cells. Evaluation of phosphorylated levels of CREB and ERK, transcriptional regulators associated with serotonin receptor signalling in osteoblasts, revealed aberrant 5HTR1B signalling in COS. Our results confirm the presence of 5HTR1B in a canine osteosarcoma cell line and highlight this receptor as a possible novel therapeutic target. © 2014 John Wiley & Sons Ltd.

  4. Highly Efficient One-Pot Synthesis of COS-Based Block Copolymers by Using Organic Lewis Pairs.

    Science.gov (United States)

    Yang, Jia-Liang; Cao, Xiao-Han; Zhang, Cheng-Jian; Wu, Hai-Lin; Zhang, Xing-Hong

    2018-01-31

    A one-pot synthesis of block copolymer with regioregular poly(monothiocarbonate) block is described via metal-free catalysis. Lewis bases such as guanidine, quaternary onium salts, and Lewis acid triethyl borane (TEB) were equivalently combined and used as the catalysts. By using polyethylene glycol (PEG) as the macromolecular chain transfer agent (CTA), narrow polydispersity block copolymers were obtained from the copolymerization of carbonyl sulfide (COS) and propylene oxide (PO). The block copolymers had a poly(monothiocarbonate) block with perfect alternating degree and regioregularity. Unexpectedly, the addition of CTA to COS/PO copolymerization system could dramatically improve the turnover frequency (TOF) of PO (up to 240 h -1 ), higher than that of the copolymerization without CTA. In addition, the conversion of CTA could be up to 100% in most cases, as revealed by ¹H NMR spectra. Of consequence, the number-average molecular weights ( M n s) of the resultant block copolymers could be regulated by varying the feed ratio of CTA to PO. Oxygen-sulfur exchange reaction (O/S ER), which can generate randomly distributed thiocarbonate and carbonate units, was effectively suppressed in all of the cases in the presence of CTA, even at 80 °C. This work presents a versatile method for synthesizing sulfur-containing block copolymers through a metal-free route, providing an array of new block copolymers.

  5. First genetic linkage map of Taraxacum koksaghyz Rodin based on AFLP, SSR, COS and EST-SSR markers

    Science.gov (United States)

    Arias, Marina; Hernandez, Monica; Remondegui, Naroa; Huvenaars, Koen; van Dijk, Peter; Ritter, Enrique

    2016-01-01

    Taraxacum koksaghyz Rodin (TKS) has been studied in many occasions as a possible alternative source for natural rubber production of good quality and for inulin production. Some tire companies are already testing TKS tire prototypes. There are also many investigations on the production of bio-fuels from inulin and inulin applications for health improvement and in the food industry. A limited amount of genomic resources exist for TKS and particularly no genetic linkage map is available in this species. We have constructed the first TKS genetic linkage map based on AFLP, COS, SSR and EST-SSR markers. The integrated linkage map with eight linkage groups (LG), representing the eight chromosomes of Russian dandelion, has 185 individual AFLP markers from parent 1, 188 individual AFLP markers from parent 2, 75 common AFLP markers and 6 COS, 1 SSR and 63 EST-SSR loci. Blasting the EST-SSR sequences against known sequences from lettuce allowed a partial alignment of our TKS map with a lettuce map. Blast searches against plant gene databases revealed some homologies with useful genes for downstream applications in the future. PMID:27488242

  6. Development of a Roebel-cable-based cosθ dipole: design and windability of magnet ends

    CERN Document Server

    Lorin, Clément; Fazilleau, Philippe; Kirby, Glyn; Rossi, Lucio

    2016-01-01

    In the scope of the Future Circular Collider, work package 10, namely “Future Magnets”, of the EuCARD2 project aims at investigating accelerator quality magnets made of High Temperature Superconductors. The present paper deals with development of a cosθ dipole relying on Roebel cable technology. In the first part, we present in details the design of the dipole: the magnet generates 5 T in stand-alone mode with an overall current density of 684 A/mm². When operating in a background field of 13 T an extra field of 2 T can be provided by the cosθ insert due to mechanical limitations. A field increase up to 2.5 T is conceivable providing the addition of inner shell reinforcement that would reduce the magnet aperture from 40 mm to 30 mm. In the second part, winding tests of dummy Roebel cable are reported. They demonstrate the challenges stemming from the relative slippage of the cable tapes while winding that may be overcome by a lengthening of the longitudinal gap of the cable either by an increase of the...

  7. visCOS: An R-package to evaluate model performance of hydrological models

    Science.gov (United States)

    Klotz, Daniel; Herrnegger, Mathew; Wesemann, Johannes; Schulz, Karsten

    2016-04-01

    The evaluation of model performance is a central part of (hydrological) modelling. Much attention has been given to the development of evaluation criteria and diagnostic frameworks. (Klemeš, 1986; Gupta et al., 2008; among many others). Nevertheless, many applications exist for which objective functions do not yet provide satisfying summaries. Thus, the necessity to visualize results arises in order to explore a wider range of model capacities, be it strengths or deficiencies. Visualizations are usually devised for specific projects and these efforts are often not distributed to a broader community (e.g. via open source software packages). Hence, the opportunity to explicitly discuss a state-of-the-art presentation technique is often missed. We therefore present a comprehensive R-package for evaluating model performance by visualizing and exploring different aspects of hydrological time-series. The presented package comprises a set of useful plots and visualization methods, which complement existing packages, such as hydroGOF (Zambrano-Bigiarini et al., 2012). It is derived from practical applications of the hydrological models COSERO and COSEROreg (Kling et al., 2014). visCOS, providing an interface in R, represents an easy-to-use software package for visualizing and assessing model performance and can be implemented in the process of model calibration or model development. The package provides functions to load hydrological data into R, clean the data, process, visualize, explore and finally save the results in a consistent way. Together with an interactive zoom function of the time series, an online calculation of the objective functions for variable time-windows is included. Common hydrological objective functions, such as the Nash-Sutcliffe Efficiency and the Kling-Gupta Efficiency, can also be evaluated and visualized in different ways for defined sub-periods like hydrological years or seasonal sections. Many hydrologists use long-term water-balances as a

  8. Chinese Climate Policy - Institutions and Intent

    International Nuclear Information System (INIS)

    Ramsay, William C.; Lesourne, Jacques; Andrews-Speed, Philip; Yishan, Xia; Dezhao, Chen

    2011-06-01

    . Not surprisingly, institutions and practices continue to reflect millennia of Chinese history, which in some measure focused on nurturing the authority of an emperor. Students of China, who have long recognized its 'command and control' economy, are now aware of the limits of those concepts and the consequences of a bureaucratic hierarchy living in a sometimes conflicted condominium with the Communist Party, even as the economy surges on. The second study seeks to answer the questions: What are the economic and strategic drivers of Chinese energy policy? How does China plan to manage its increasing reliance on foreign sources of oil, gas and now coal? How will these drivers shape the guiding principles of Chinese national companies and their relations with international operators and foreign sources of energy resources? How does China define and shape its international diplomacy and practices in order to succeed in its quest to secure access to upstream oil, gas, coal and uranium - just to mention the fuels? The third study explores the Chinese approach to climate change. The Chinese have long been victims of their own internal deserts and know only too well the challenges that the power of nature imposes on their society. The recent spectacular growth of the Chinese economy has left China with a plethora of weeping environmental wounds. While these are increasingly urgent short-term challenges, Chinese leaders are only too aware that, in the longer term, under any probable climate change scenario, China is a loser

  9. American Society of Hematology

    Science.gov (United States)

    ... Navigation Account Navigation Main Content American Society of Hematology ASH Store ASH Job Center ASH Apps Share ... youtube linkedin Research In This Section Agenda for Hematology Research Sickle Cell Priorities Lymphoma Roadmap Moonshot Initiative ...

  10. American Society of Anesthesiologists

    Science.gov (United States)

    ... Trauma ASA and CAE Healthcare’s virtual O.R. Popular Courses Member Exclusive Difficult Airway Algorithm Member login ... You Industry Supporters Whose contributions allow the American Society of Anesthesiologists ® to create world-class education and ...

  11. Society for Ambulatory Anesthesia

    Science.gov (United States)

    ... SAMBA Link Digital Newsletter Educational Bibliography Research IARS/Anesthesia & Analgesia SCOR About SCOR Sponsor SAMBA Meetings Affinity Sponsor Program We Represent Ambulatory and Office-Based Anesthesia The Society for Ambulatory Anesthesia provides educational opportunities, ...

  12. International Transplant Nurses Society

    Science.gov (United States)

    ... The term "clinical ladder" refers to a "grading structure which facilitates career progression and associated differentiation of ... 20-1589538 Copyright © 2006 - 2014 International Transplant Nurses Society (ITNS). No materials, including graphics, may be reused, ...

  13. Valie EXPORT Society. Overlok

    Index Scriptorium Estoniae

    2001-01-01

    Valie EXPORT Society asutasid 23. okt. 1999. a. Frankfurdis Kadi Estland, Killu Sukmit ja Mari Laanemets, kui olid külastanud austria naiskunstniku Valie Exporti näitust. Rühmituse aktsioonide kirjeldus

  14. Valie EXPORT Society Rooseumis

    Index Scriptorium Estoniae

    2002-01-01

    Malmös Rooseumi Kaasaegse Kunsti Keskuses näitus "Baltic Babel". Projekt koosneb Läänemeremaade linnades tegutsevate innovatiivsete gruppide aktsioonidest. Kuraator Charles Esche. Esinejatest (Eestist Valie Export Society: Kadi Estland, Killu Sukmit)

  15. American Epilepsy Society

    Science.gov (United States)

    ... for the AES Annual Meeting. More info here . Epilepsy Currents American Epilepsy Society Journal Impact Factor More ... P450 enzyme overexpression during spontaneous recurrent seizures More Epilepsy Professional News AES Status Epilepticus guideline for treatment ...

  16. Changing Anthropology, Changing Society

    Science.gov (United States)

    Varughese, Heather

    2009-01-01

    Fifty years after the founding of the field of medical anthropology, the Society for Medical Anthropology of the American Anthropological Association held its first independent meeting on September 24-27, 2009, at Yale University. PMID:20027281

  17. Transnationalising Civil Society?

    DEFF Research Database (Denmark)

    Jørgensen, Martin Bak

    The paper takes a transnational perspective on developing an analytical framework for understanding how transnationalism interacts with civil society and how immigrant organisations use transnational strategies to challenge the pre-given positions of immigrants within given integration- and citiz......The paper takes a transnational perspective on developing an analytical framework for understanding how transnationalism interacts with civil society and how immigrant organisations use transnational strategies to challenge the pre-given positions of immigrants within given integration...

  18. Nuclear technology and society

    International Nuclear Information System (INIS)

    Suzuki, Tatsujiro; Tanaka, Yutaka; Taniguchi, Taketoshi; Oyama, Kosuke

    1999-01-01

    This special issue of Journal of the Atomic Energy Society of Japan deals with the relation between nuclear technology and society, and is composed of four papers: (1) Nuclear energy and international politics - sociotechnics around plutonium utilization; (2) Risk recognition and benefit recognition of nuclear facilities and social acceptance; (3) Environmental risk management and radioactive waste problem; and, (4) Public administration around the relation between nuclear energy and society. (1) describes the historical development of nuclear energy since its birth, focusing on how the leading countries tried to control nuclear proliferation. Peaceful utilization of nuclear energy is closely connected with the Non-proliferation problem. (1) also discusses the relation of plutonium utilization of Japan with international society. (2) discusses how nuclear facilities can be accepted by society, analyzing the background of risk recognition, in particular, of psychological character of mass society. (3) introduces an new approach (risk-based or risk-informed regulation) of environmental risk management for radioactive waste disposal problem, focusing on HLW (high-level waste). (4) explains the approach from public administration to nuclear energy and general energy policy and introduces PPA (participatory policy analysis) as a means for policy making. (M.M.)

  19. Fermi Surface and Magnetic Properties in Ferromagnet CoS2 and Paramagnet CoSe2 with the Pyrite-type Cubic Structure

    Science.gov (United States)

    Teruya, A.; Suzuki, F.; Aoki, D.; Honda, F.; Nakamura, A.; Nakashima, M.; Amako, Y.; Harima, H.; Uchima, K.; Hedo, M.; Nakama, T.; Ōnuki, Y.

    2017-02-01

    We succeeded in growing high-quality single crystals of pyrite-type cubic compounds CoSe2 and CoS2 using a transport agent of CoBr2 and measured the electrical resistivity, specific heat, magnetic susceptibility, magnetization, and the de Haas-van Alphen (dHvA) effect. We confirmed that CoSe2 is an exchange-enhanced paramagnet revealing a broad maximum at around 50 K in the temperature dependence of the magnetic susceptibility. The electronic specific heat coefficient is moderately large, γ = 18 mJ/(K2·mol). On the other hand, CoS2 is a ferromagnet with a Curie temperature T C = 122 K and an ordered moment μ s = 0.93 μB/Co. The γ value of 21 mJ/(K2·mol) in CoS2 is slightly larger than that of CoSe2. A large ordered moment, together with a large γ value, is a characteristic feature in CoS2 because CoS2 is a half-metallic spin state in the ferromagnetic state. Correspondingly, we detected a main dHvA branch with a large cyclotron effective mass of 13m 0 in the dHvA experiments. The detected dHvA branches in CoS2 and CoSe2 are discussed on the basis of the results of energy band calculations, revealing a broken four-fold-symmetry in the angular dependence of the dHvA frequency.

  20. The Society for Scandinavian Art

    DEFF Research Database (Denmark)

    Grand, Karina Lykke

    2016-01-01

    The Society for Nordic Art & the Scandinavian Society [Selskabet for Nordisk Kunst & Skandinavisk Selskab]......The Society for Nordic Art & the Scandinavian Society [Selskabet for Nordisk Kunst & Skandinavisk Selskab]...

  1. Russian – Chinese Trade and Exchange Rate

    Directory of Open Access Journals (Sweden)

    Dmitry Alexandrovich Izotov

    2012-09-01

    Full Text Available The author assesses the impact of the Yuan exchange rate volatility on the indicators of the Russian-Chinese trade (the analysis is made on the ground of the statistical database CEIC. Quantitative estimates of changes in Russian-Chinese merchandise trade by commodity groups (in the HS classification due to the revaluation of the CNY against the USD were obtained via the regression analysis. In the case of the revaluation of the Yuan to the US dollar the value of Russian exports may increase for such commodity groups as mineral products, chemical industry products, base metals, precious stones and metals, and vehicles. This article shows that the value of Chinese imports will decrease for such merchandise groups as transport vehicles, machinery and equipment, leather industry products, non-precious metals and products from them; in this case, the import of the food industry products, mineral products and optical instruments will decrease insignificantly. The author concludes that the revaluation of the Yuan, contributing to the growth of Russian exports and the reduction in Chinese imports, will not cause a radical change in structure of the Russian-Chinese trade

  2. Different facets of compulsive buying among Chinese students

    OpenAIRE

    LI, SHUANG; UNGER, ALEXANDER; BI, CHONGZENG

    2014-01-01

    Background and aims: Compulsive buying is a severe phenomenon, especially among younger consumers. It is well documented in Western industrial societies like the USA and Germany, and nowadays an increasing interest in compulsive buying in non-Western countries is on the rise. Methods: In the current study, we measured the prevalence of compulsive buying tendencies among Chinese female and male students by using a Chinese translation of the German Compulsive Buying Scale (Raab, Neuner, Reisch ...

  3. Circumostial injection of mitomycin C (COS-MMC) in external and endoscopic dacryocystorhinostomy: efficacy, safety profile, and outcomes.

    Science.gov (United States)

    Kamal, Saurabh; Ali, Mohammad Javed; Naik, Milind N

    2014-01-01

    To evaluate the safety and efficacy of a new technique of circumostial mitomycin C (COS-MMC) injection in dacryocystorhinostomy (DCR) and to evaluate the outcomes. A prospective, interventional consecutive case series involving 110 DCR surgeries performed over a period of 1 year using the COS-MMC technique were evaluated. All patients were operated by a single surgeon (M.J.A.). After fashioning of the mucosal flaps, all patients underwent an intramucosal injection of 0.02% MMC at 4 points (0.1 ml at each point) along the edges of the freshly created ostium. All patients were intubated, and stent removal was done at 12 weeks following the surgery. All patients underwent regular monitoring of the ostium to look for any complications. A minimum follow up of 6 months after stent removal was considered for final analysis. The outcome measures analyzed were anatomical and functional success, complications, and ostium. The mean age at presentation was 39.91 years. The diagnosis was primary acquired nasolacrimal duct obstruction in 60.9% (67/110) and persistent congenital nasolacrimal duct obstruction in 9.1% (10/110) of the patients. Twenty-six patients were known cases of failed DCR and underwent a revision DCR. Of the total patients, 19.1% (21/110) had a history of acute dacryocystitis, of which, 73% (80/110) of the surgeries were performed by an external approach and 27% (30/110) by endoscopic endonasal route. Anatomical success was noted in 97.3% (107/110) and functional success in 96.4% (106/110). All the 4 failures were due to cicatricial closure of the ostium. None of the patients were noted to have mucosal burns in the area where MMC was injected, and none of the Ostia showed any features of necrosis, infection, or any other complications. COS-MMC is a safe and effective adjunctive modality in DCR. No adverse effects on the ostium were noted. The technique appears to be promising for the success of cases with high risk of failures like revision DCR and traumatic

  4. Civil society sphericules

    DEFF Research Database (Denmark)

    Tufte, Thomas

    2014-01-01

    the organization strategizes about and seeks to articulate amongst Tanzanian youth. Situated in the ‘perverse confluence’ (Dagnino, 2011) between neoliberal and radical democratic agendas in the communicative practices of civil society-driven media platforms, Femina navigates between identities as an NGO, a social...... movement and a media initiative. In the context of the growing literature on social networking sites and their affordances, dynamics and structures, the case of Femina illustrates how a civil society sphericule emerges within the dynamic co-evolution of new and old media platforms. The study is furthermore...... an example of the difficult shift in civil society practice, from service provision to an agenda of public service monitoring, social accountability and community engagement....

  5. Society and education

    DEFF Research Database (Denmark)

    Moutsios, Stavros

    in Europe. Elaborating on the Castoriadian ontology, the book delves into the magma of social imaginary significations that characterise and associate pivotal epochs of the continent’s history, Classical Greece and Modernity, and exemplifies their incarnation in educational systems and in the formation......'Society and Education: An Outline of Comparison' explores the relation of society to education in Europe, as well as its comparative perspective towards overseas societies and their institutions. It is an enquiry into the social-historical institution of education and cross-cultural studies...... of the European and, in general, the Western comparative gaze. With a particular focus on our epoch, Postmodernity and globalisation, the study traces the pervasive dominance of capitalist significations in social institutions, forms, and activities, as well as in education and the way it is compared across...

  6. Ethnic identity of older Chinese in Canada.

    Science.gov (United States)

    Lai, Daniel W L

    2012-06-01

    In Canada's multicultural society, ethnic identity is important to the elderly and can influence areas such as access to services, health promotion and care. Often, the complex nature of ethnic identity is underestimated when looking at cultural groups. This study aims to: (a) validate the factor structure of a Chinese ethnic identity measure for older Chinese in Canada, (b) examine the level of ethnic identity of the participants, and (c) examine the correlates of ethnic identity in these older individuals. Using data from a large, national research project on the elderly Chinese in Canada, this study analyzed the results gathered from a total of 2,272 participants. Principal component analysis, maximum-likelihood confirmatory factor analysis, and multiple regression analysis were performed. The results indicated that ethnic identity of the older Chinese is a multi-dimensional construct made up of three factors: (a) culture related activities, (b) community ties, (c) linkage with country of origin, and (d) cultural identification. The findings have provided a better understanding of how ethnic identity can be measured among the aging Chinese population in Canada.

  7. Living in Two Cultures: Chinese Canadians' Perspectives on Health.

    Science.gov (United States)

    Lu, Chunlei; McGinn, Michelle K; Xu, Xiaojian; Sylvestre, John

    2017-04-01

    Chinese people have distinctive perspectives on health and illness that are largely unrecognized in Western society. The purpose of this descriptive study was to develop a profile of Chinese immigrants' beliefs and practices related to diet, mental and social health, and sexual health. A quantitative survey with descriptive and correlational analyses was employed to examine 100 first-generation Chinese immigrants living in four urban centres across Canada (Vancouver, Toronto, Halifax, and St. Catharines). Although most Chinese immigrants preferred a Chinese diet, where they resided affected the groceries they bought and the meals they ate. Almost all participants reported their mental health was important to them and most felt comfortable discussing mental health issues with others. However, only a third would see a psychiatrist if they believed they had a mental health problem. Most participants believed social relationships were important for their health. Only a small number of participants, however, preferred making friends with mainstream Caucasian Canadians. More men than women believed sexuality contributed to health and were comfortable talking about sexual health. Chinese immigrants should be encouraged to be more engaged in the larger community in order to fully integrate themselves into Canadian society while still being encouraged to retain their healthy practices. These findings may help educators and practitioners enhance their understandings of Chinese immigrants' perspectives on health and develop culturally competent education and services in health care and health promotion.

  8. Science and Society Colloquium

    CERN Multimedia

    Randi, J

    1991-01-01

    Mr. Randi will give an update of his lecture to the American Physical Society on the occasion of his award of the 1989 Forum Prize. The citation said: "for his unique defense of Science and the scientific method in many disciplines, including physics, against pseudoscience, frauds and charlatans. His use of scientific techniques has contributed to refuting suspicious and fraudulent claims of paranormal results. He has contributed significantly to public understanding of important issues where science and society interact". He is a professional magician and author of many books. He worked with John Maddox, the Editor of Nature to investigate the claims of "water with memory".

  9. European Respiratory Society statement

    DEFF Research Database (Denmark)

    Miravitlles, Marc; Dirksen, Asger; Ferrarotti, Ilaria

    2017-01-01

    lung disease. A large proportion of individuals affected remain undiagnosed and therefore without access to appropriate care and treatment.The most recent international statement on AATD was published by the American Thoracic Society and the European Respiratory Society in 2003. Since then there has...... the efficacy and safety of augmentation therapy, the only specific treatment available for the pulmonary disease associated with AATD.As AATD is a rare disease, it is crucial to organise national and international registries and collect information prospectively about the natural history of the disease...

  10. Advanced information society(7)

    Science.gov (United States)

    Chiba, Toshihiro

    Various threats are hiding in advanced informationalized society. As we see car accident problems in motorization society light aspects necessarily accompy shady ones. Under the changing circumstances of advanced informationalization added values of information has become much higher. It causes computer crime, hacker, computer virus to come to the surface. In addition it can be said that infringement of intellectual property and privacy are threats brought by advanced information. Against these threats legal, institutional and insurance measures have been progressed, and newly security industry has been established. However, they are not adequate individually or totally. The future vision should be clarified, and countermeasures according to the visions have to be considered.

  11. Chinese Principles of Operational Deception

    National Research Council Canada - National Science Library

    Murphy, Jr, Michael

    2006-01-01

    .... An analysis of Chinese employment of operational deception in each modern day Chinese conflict since the Chinese Civil War determines that China's principles of operation match those of the United States...

  12. State and society in Asia.

    Science.gov (United States)

    Mittal, S P

    1986-03-01

    India and China are the 2 most populous countries of the world; in the 1950s, both countries initiated a centrally planned program for rapid development within vastly differing political systems. China embarked India's policy encouraged only voluntary acceptance of family planning. In both cases, however, government involvement in population forms a part of comprehensive national planning. Both countries rely on a limited resource base and technological sophistication in order to alleviate mass poverty and misery. The political implications of population growth cannot be neatly isolated from those that are generated by social and economic forces of change in a society that is in a transitional stage of modernization and development. Development has not been an unmixed bleesing; population growth is one of its counterproductive outcomes. The development process has begun to draw increasing attention to hitherto neglected correlates of fertility decline, such as a reduction in infant mortality, universal education, improvement in women's status, and women's participation in economic activity outside the home, all of which eventually result in greater demand for family planning services. Both the Indian and Chinese models highlight the importance of taking the people into one's confidence; the response of the common people to official initiatives is critical in securing a reduction in fertility levels. China has adopted a 1 child family policy, yet it is unreasonable to expect that the Indian people would agree to a nationally prescribed family size norm below 2 children. The principal determinant of future population trends in both these countries is the course of their politics. The success of developing countries will be assured if the developed nations support their progress without being worried about their population growth, which is the result of their unavoidable failure to modernize their social and economic structures.

  13. Examination of the Position Accuracy of Implant Abutments Reproduced by Intra-Oral Optical Impression.

    Directory of Open Access Journals (Sweden)

    Hitoshi Ajioka

    Full Text Available An impression technique called optical impression using intraoral scanner has attracted attention in digital dentistry. This study aimed to evaluate the accuracy of the optical impression, comparing a virtual model reproduced by an intraoral scanner to a working cast made by conventional silicone impression technique. Two implants were placed on a master model. Working casts made of plaster were fabricated from the master model by silicone impression. The distance between the ball abutments and the angulation between the healing abutments of 5 mm and 7 mm height at master model were measured using Computer Numerical Control Coordinate Measuring Machine (CNCCMM as control. Working casts were then measured using CNCCMM, and virtual models via stereo lithography data of master model were measured by a three-dimensional analyzing software. The distance between ball abutments of the master model was 9634.9 ± 1.2 μm. The mean values of trueness of the Lava COS and working casts were 64.5 μm and 22.5 μm, respectively, greater than that of control. The mean of precision values of the Lava COS and working casts were 15.6 μm and 13.5 μm, respectively. In the case of a 5-mm-height healing abutment, mean angulation error of the Lava COS was greater than that of the working cast, resulting in significant differences in trueness and precision. However, in the case of a 7-mm-height abutment, mean angulation errors of the Lava COS and the working cast were not significantly different in trueness and precision. Therefore, distance errors of the optical impression were slightly greater than those of conventional impression. Moreover, the trueness and precision of angulation error could be improved in the optical impression using longer healing abutments. In the near future, the development of information technology could enable improvement in the accuracy of the optical impression with intraoral scanners.

  14. Examination of the Position Accuracy of Implant Abutments Reproduced by Intra-Oral Optical Impression

    Science.gov (United States)

    Odaira, Chikayuki; Kobayashi, Takuya; Kondo, Hisatomo

    2016-01-01

    An impression technique called optical impression using intraoral scanner has attracted attention in digital dentistry. This study aimed to evaluate the accuracy of the optical impression, comparing a virtual model reproduced by an intraoral scanner to a working cast made by conventional silicone impression technique. Two implants were placed on a master model. Working casts made of plaster were fabricated from the master model by silicone impression. The distance between the ball abutments and the angulation between the healing abutments of 5 mm and 7 mm height at master model were measured using Computer Numerical Control Coordinate Measuring Machine (CNCCMM) as control. Working casts were then measured using CNCCMM, and virtual models via stereo lithography data of master model were measured by a three-dimensional analyzing software. The distance between ball abutments of the master model was 9634.9 ± 1.2 μm. The mean values of trueness of the Lava COS and working casts were 64.5 μm and 22.5 μm, respectively, greater than that of control. The mean of precision values of the Lava COS and working casts were 15.6 μm and 13.5 μm, respectively. In the case of a 5-mm-height healing abutment, mean angulation error of the Lava COS was greater than that of the working cast, resulting in significant differences in trueness and precision. However, in the case of a 7-mm-height abutment, mean angulation errors of the Lava COS and the working cast were not significantly different in trueness and precision. Therefore, distance errors of the optical impression were slightly greater than those of conventional impression. Moreover, the trueness and precision of angulation error could be improved in the optical impression using longer healing abutments. In the near future, the development of information technology could enable improvement in the accuracy of the optical impression with intraoral scanners. PMID:27706225

  15. Cos-$\\theta$ design of dipole inserts made of ReBCO-Roebel or BSCCO-Rutherford cables

    CERN Document Server

    Lorin, C; Fazilleau, P; Pes, C; Rifflet, J M; Segreti, M; Ballarino, A; Bottura, L; Fleiter, J; Kirby, G; Rossi, L; Van Nugteren, J

    2015-01-01

    Next generation of dipole magnets with field higher than 16 T are considered for future particle colliders. To do so, combined-technology magnets - made of Nb-Ti, Nb$_{3}$Sn and HTS materials - have to be developed to reduce the cost of such a magnet. Therefore, in the framework of the EuCARD-2 project, many HTS dipole magnet designs have to be investigated so as to find the most effective design for the HTS insert in a graded magnet. This paper discusses the Cosθ option. A 5 T standalone configuration of the HTS accelerator magnet (the first goal of EuCARD2) appears to be achievable, whereas mechanical stress distribution shows that its use as insert in graded magnet is very challenging. This paves the way for alternative designs as the so-called slot or motor-like design, briefly introduced here.

  16. Beta-galactosidase-deficient human fibroblasts: uptake and processing of the exogenous precursor enzyme expressed by stable transformant COS cells.

    Science.gov (United States)

    Oshima, A; Itoh, K; Nagao, Y; Sakuraba, H; Suzuki, Y

    1990-10-01

    COS-1 cells were transfected by electroporation with a cDNA for human acid beta-galactosidase cloned in our laboratory and stable transformants expressing the enzyme activity were selected. The precursor form of the enzyme was secreted in large quantities into the culture medium. The fibroblasts from patients with GM1-gangliosidosis or Morquio B disease showed a remarkable increase of enzyme activity, up to the normal level, after culture in this medium for 2 days; the amount of uptake was essentially the same as that for the precursor form in human fibroblasts. After endocytosis, the precursor molecules were processed normally to the mature form and remained as stable as those produced by human fibroblasts. On the other hand, cells from galactosialidosis patients did not show any increase of enzyme activity in a similar experiment. It was concluded that the transformants are useful as the source of precursor proteins for the study of intracellular turnover of enzyme molecules in mutant cells.

  17. The interface of the ferromagnetic metal CoS2 and the nonmagnetic semiconductor FeS2

    KAUST Repository

    Nazir, S.

    2010-11-05

    The electronic and magnetic properties of the cubic pyriteCoS2/FeS2interface are studied using the all-electron full-potential linearized augmented plane wave method. We find that this contact between a ferromagneticmetal and a nonmagnetic semiconductor shows a metallic character. The CoS2 stays close to half-metallicity at the interface, while the FeS2 becomes metallic. The magnetic moment of the Co atoms at the interface slightly decreases as compared to the bulk value and a small moment is induced on the Fe atoms. Furthermore, at the interfaceferromagnetic ordering is found to be energetically favorable as compared to antiferromagnetic ordering.

  18. Study on Chinese Low Carbon Economic Model

    OpenAIRE

    Huifeng Li; Xiaofang Wang

    2010-01-01

    Global warming, which is caused by over consumption of fossil energy during economic development in human society, threatens global ecological balance, tampers social and economic development, imperils energy security, ecological safety, water and food safety, and endangers the entire human race. Low carbon economy is a new economic development model based on low energy consumption, low pollution, and low-emission-based. This paper analyzes the Status quo and Limits of the Chinese Low Carbon ...

  19. Optic neuritis

    Science.gov (United States)

    Retro-bulbar neuritis; Multiple sclerosis - optic neuritis; Optic nerve - optic neuritis ... The exact cause of optic neuritis is unknown. The optic nerve carries visual information from your eye to the brain. The nerve can swell when ...

  20. Society of Thoracic Surgeons

    Science.gov (United States)

    ... Society of Thoracic Surgeons Facebook Twitter LinkedIn YouTube Instagram Flickr About STS Governance and Leadership Bylaws Policies ... Tweets by @STS_CTsurgery Facebook Twitter LinkedIn YouTube Instagram Flickr Footer menu Home Contact Us CT Surgery ...

  1. Exploratory of society

    Science.gov (United States)

    Cederman, L.-E.; Conte, R.; Helbing, D.; Nowak, A.; Schweitzer, F.; Vespignani, A.

    2012-11-01

    A huge flow of quantitative social, demographic and behavioral data is becoming available that traces the activities and interactions of individuals, social patterns, transportation infrastructures and travel fluxes. This has caused, together with innovative computational techniques and methods for modeling social actions in hybrid (natural and artificial) societies, a qualitative change in the ways we model socio-technical systems. For the first time, society can be studied in a comprehensive fashion that addresses social and behavioral complexity. In other words we are in the position to envision the development of large data and computational cyber infrastructure defining an exploratory of society that provides quantitative anticipatory, explanatory and scenario analysis capabilities ranging from emerging infectious disease to conflict and crime surges. The goal of the exploratory of society is to provide the basic infrastructure embedding the framework of tools and knowledge needed for the design of forecast/anticipatory/crisis management approaches to socio technical systems, supporting future decision making procedures by accelerating the scientific cycle that goes from data generation to predictions.

  2. The Doctor and Society*

    African Journals Online (AJOL)

    The doctor, no less than any other scientist, is a member of society. His situation, however, is unique, inasmuch as in an age of technocracy he must remain human. Despite the pressure of his own discipline he should be an edu- cated person in the general meaning of the word. The necessary attributes of this state are ...

  3. Libraries in society

    DEFF Research Database (Denmark)

    Kristiansson, Michael; Skouvig, Laura Henriette Christine

    2008-01-01

    brought about by the boom of the internet and the advent of the post-modern globalised knowledge-based and network-organised society. Finally, the paper outlines how theoretical and strategic library development can benefit from academic considerations on the dialectics between openness and restrictedness...

  4. Italian Society of Physics

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    The abstracts of most of the papers read at the 53 National Congress of the Italian Society of Physics are presented. The Congress developed in ten sessions: high energy and elementary particle physics, physics of nuclei, condensed matter, quantum electronics, cosmic physics, geophysics, general physics, electronics and applied physics, health physics and hystory of physics. An author index is also included

  5. Big Society, Big Deal?

    Science.gov (United States)

    Thomson, Alastair

    2011-01-01

    Political leaders like to put forward guiding ideas or themes which pull their individual decisions into a broader narrative. For John Major it was Back to Basics, for Tony Blair it was the Third Way and for David Cameron it is the Big Society. While Mr. Blair relied on Lord Giddens to add intellectual weight to his idea, Mr. Cameron's legacy idea…

  6. Reintegrating ghettos into society

    DEFF Research Database (Denmark)

    Mechlenborg, Mette

    2018-01-01

    In 2010, the Danish government launched a ghetto strategy with 32 initiatives in order to “dissolve parallel communities” in Danish housing areas and to (re)integrate them into Danish society (Statsministeret, 2010). Despite its negative offspring in the Muhammed riots (Freiesleben 2016, Houlind...

  7. MARX EMBRYOLOGY OF SOCIETY

    NARCIS (Netherlands)

    WOUTERS, A

    This article presents a new interpretation of Marx's dialectical method. Marx conceived dialectics as a method for constructing a model of society. The way this model is developed is analogous to the way organisms develop according to the German embryologist Karl Ernst von Baer, and, indeed, Marx's

  8. Filling the Void: A Comprehensive Survey of the Intergalactic Medium at z 1 Using STIS/COS Archival Spectra

    Science.gov (United States)

    Khaire, Vikram

    2017-08-01

    There exists a large void in our understanding of the intergalactic medium (IGM) at z=0.5-1.5, spanning a significant cosmic time of 4 Gyr. This hole resulted from a paucity of near-UV QSO spectra, which were historically very expensive to obtain. However, with the advent of COS and the HST UV initiative, sufficient STIS/COS NUV spectra have finally become available, enabling the first statistical analyses. We propose a comprehensive study of the z 1 IGM using the Ly-alpha forest of 26 archival QSO spectra. This analysis will: (1) measure the distribution of HI absorbers to several percent precision down to log NHI background (UVB) at that epoch; (2) measure the Ly-alpha forest power spectrum to 12%, providing another precision test of LCDM and our theory of the IGM; (3) measure the thermal state of the IGM, which reflects the balance of heating (photoheating, HI/HeII reionization) and cooling (Hubble expansion) of cosmic baryons, and directly verify the predicted cooldown of IGM gas after reionization for the first time; (4) generate high-quality reductions, coadds, and continuum fits that will be released to the public to enable other science cases. These results, along with our state-of-the-art hydrodynamical simulations, and theoretical models of the UVB, will fill the 4 Gyr hole in our understanding of the IGM. When combined with existing HST and ground-based data from lower and higher z, they will lead to a complete, empirical description of the IGM from HI reionization to the present, spanning more than 10 Gyr of cosmic history, adding substantially to Hubble's legacy of discovery on the IGM.

  9. Radiation protection and society

    International Nuclear Information System (INIS)

    Skryabin, A.M.

    1997-01-01

    The radiological protection of population, living on the contaminated territories, is actual 10 years after the Chernobyl accident. Eventually, the whole system of countermeasures application is aimed to protect society as a complex community of individuals . The variety of levels of society, i.e. family, settlement on the whole, can be considered as certain harmonic systems differing in their public consciousness levels and lifestyles, this explain the difference in their 'behaviour' in terms of radiation protection and attitude to the information obtained. Each level of society possesses a certain degree of liberty of choice, that finally influence the magnitude and the character of dose distribution within certain population groups. In general, the dose distribution in the settlement can be explained only on the bases of 'family' analysis. This concerns the rural settlement as a society too. All rural settlement can be divided into two or three classes: with low, high and intermediate social features. Small settlements (< 100 persons), where the advanced in age persons with low material income and high degree of natural economy are applied to the first class. This results in higher doses (2-3 fold), than in the settlements with higher social level. The analysis shows that in socially 'waning' settlements the countermeasures are less efficient and the term of their action is shorter. (this class is the largest, About 50% among all the rural settlements). Due to the deterioration of the economic situation in the Republic of Belarus after 1991-1992 resulted in the increase of doses mainly in the habitants first of all of this class of settlements. It seems problematic to increase countermeasures efficiency in this class of settlements without the refuse of the accustomed lifestyle and radical improvement of social-demographic and economic conditions. The present material shows the necessity of the differential approach based on 'society-analysis' in the

  10. Ambiguity-Free Measurement of cos2beta: Time-Intergrated and Time-Dependent Angular Analyses of B to J/psi K pi

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2004-11-02

    We present results on B {yields} J/{psi} K{pi} decays using e{sup +}e{sup -} annihilation data collected with the BABAR detector at the {Upsilon}(4S) resonance. The detector is located at the PEP-II asymmetric-energy storage ring facility at the Stanford Linear Accelerator Center. Using approximately 88 million B{bar B} pairs, we measure the decay amplitudes for the flavor eigenmodes and observe strong-phase differences indicative of final-state interactions with a significance of 7.6 standard deviations. We use the interference between the K{pi} S-wave and P-wave amplitudes in the region of the K*(892) to resolve the ambiguity in the determination of these strong phases. We then perform an ambiguity-free measurement of cos 2{beta} using the angular and time-dependent asymmetry in B {yields} J/{psi} K*{sup 0} (K{sub S}{sup 0}{pi}{sup 0}) decays. With sin2{beta} fixed at its measured value and cos2{beta} treated as an independent parameter, we find cos 2{beta} = 2.72{sub -0.79}{sup +0.50}(stat) {+-} 0.27(syst), determining the sign of cos 2{beta} to be positive at 86% CL.

  11. Comparing the heterogeneity of copper-binding characteristics for two different-sized soil humic acid fractions using fluorescence quenching combined with 2D-COS.

    Science.gov (United States)

    Hur, Jin; Lee, Bo-Mi

    2011-01-01

    Heterogeneous distributions of copper-binding characteristics were compared for two ultrafiltered size fractions of a soil HA using fluorescence quenching combined with two-dimensional correlation spectroscopy (2D-COS). The apparent shapes of the original synchronous fluorescence spectra and the extent of the fluorescence quenching upon the addition of copper were similar for the two fractions. The stability constants calculated at their highest peaks were not significantly different. However, the 2D-COS results revealed that the fluorescence quenching behaviors were strongly affected by the associated wavelengths and the fraction's size. The spectral change preferentially occurred in the wavelength order of 467 nm → 451 nm → 357 nm for the 1-10 K fraction and of 376 nm → 464 nm for the >100 K fraction. The extent of the binding affinities exactly followed the sequential orders interpreted from the 2D-COS, and they exhibited the distinctive ranges of the logarithmic values from 5.86 to 4.91 and from 6.48 to 5.95 for the 1-10 K and the >100 K fractions, respectively. Our studies demonstrated that fluorescence quenching combined with 2D-COS could be successfully utilized to give insight into the chemical heterogeneity associated with metal-binding sites within the relatively homogeneous HA size fractions.

  12. Self-Assembled CoS Nanoflowers Wrapped in Reduced Graphene Oxides as the High-Performance Anode Materials for Sodium-Ion Batteries.

    Science.gov (United States)

    Zhao, Yingying; Pang, Qiang; Meng, Yuan; Gao, Yu; Wang, Chunzhong; Liu, Bingbing; Wei, Yingjin; Du, Fei; Chen, Gang

    2017-09-21

    It remains a big challenge to identify high-performance anode materials to promote practical applications of sodium-ion batteries. Herein, the facile synthesis of CoS nanoflowers wrapped in reduced graphene oxides (RGO) is reported, and their sodium storage properties are systematically studied in comparison with bare CoS. The CoS@RGO nanoflowers deliver a high reversible capacity of 620 mAh g -1 at a current density of 100 mA g -1 and superior rate capability with discharge capacity of 329 mAh g -1 at 4 A g -1 , much higher than those of the bare CoS. Evidenced by electrochemical impedance spectra and ex-situ SEM images, the improvement in the sodium storage performance is found to be due to the introduction of RGO which serves as a conducting matrix, to not only increase the kinetic properties of CoS, but also buffer the volume change and maintain the integrity of working electrodes during (de)sodiation processes. More importantly, the pseudocapacitive contribution of more than 89 % is only observed in the CoS@RGO nanocomposites, owing to the enhanced specific area and surface redox behavior. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Ni3S2@CoS core-shell nano-triangular pyramid arrays on Ni foam for high-performance supercapacitors.

    Science.gov (United States)

    Li, Rui; Wang, Senlin; Wang, Jianpeng; Huang, Zongchuan

    2015-07-07

    In this study, we demonstrate a facile method to fabricate novel Ni3S2 nano-triangular pyramid (NTP) arrays on Ni foam through a hydrothermal process and build unique Ni3S2@CoS core-shell NTP arrays by electro-deposition. The obtained Ni3S2@CoS material displays twice the specific capacitance of the pure Ni3S2 material in both a three-electrode system (4.89 F cm(-2) at 4 mA cm(-2)) and asymmetric supercapacitor device (0.69 F cm(-2) at 1.43 mA cm(-2)). In addition, the asymmetric supercapacitor demonstrates the outstanding energy density of 28.24 W h kg(-1) at a power density of 134.46 W kg(-1), with a stable cycle life (98.83% retained after 2000 cycles). The unique structure of the Ni3S2@CoS core-shell NTP arrays, which provides an ultra-thin CoS shell to enlarge efficient areas, introduces good conductivity, and short transportation lengths for both ions and electrons, contributes most to its excellent performance. Moreover, the bare Ni3S2 NTP arrays can be used as a new template to build other potential electrode materials.

  14. In Situ Fabrication of CoS and NiS Nanomaterials Anchored on Reduced Graphene Oxide for Reversible Lithium Storage.

    Science.gov (United States)

    Tan, Yingbin; Liang, Ming; Lou, Peili; Cui, Zhonghui; Guo, Xiangxin; Sun, Weiwei; Yu, Xuebin

    2016-06-15

    CoS and NiS nanomaterials anchored on reduced graphene oxide (rGO) sheets, synthesized via combination of hydrothermal with sulfidation process, are studied as high-capacity anode materials for the reversible lithium storage. The obtained CoS nanofibers and NiS nanoparticles are uniformly dispersed on rGO sheets without aggregation, forming the sheet-on-sheet composite structure. Such nanoarchitecture can not only facilitate ion/electron transport along the interfaces, but also effectively prevent metal-sulfide nanomaterials aggregation during the lithium reactions. Both the rGO-supported CoS nanofibers (NFs) and NiS nanoparticles (NPs) show superior lithium storage performance. In particular, the CoS NFs-rGO electrodes deliver the discharge capacity as high as 939 mA h g(-1) after the 100th cycle at 100 mA g(-1) with Coulombic efficiency above 98%. This strategy for construction of such composite structure can also synthesize other metal-sulfide-rGO nanomaterials for high-capacity lithium-ion batteries.

  15. In vitro functional test of two subclasses of an anti-RhD antibody produced by transient expression in COS cells

    DEFF Research Database (Denmark)

    Nielsen, Leif Kofoed; Norderhaug, Lars; Sandlie, Inger

    2006-01-01

    that other sources of anti-RhD will be needed. One such source is recombinant human antibodies. Here we describe the construction of plasmids encoding two subclasses (IgG1 and IgG3) of an anti-RhD antibody, their transient expression in COS cells, and subsequent functional characterization of the antibodies...

  16. Consumption in the Information Society

    Science.gov (United States)

    Zherebin, V. M.; Ermakova, N. A.; Makhrova, O. N.

    2010-01-01

    The current state of the economy in the developed countries make it possible to characterize them using concepts and terms such as the postindustrial society, the new economy, the service economy, the creative economy, the posteconomic society, the information society, the knowledge society, and the consumer society. Among these terms and…

  17. INSTITUTIONAL Change as Cultural Change. An Illustration by Chinese Postsocialist Transformation

    OpenAIRE

    EL KAROUNI, Ilyess

    2007-01-01

    Culture of a society reflects its social values. So, through Chinese experience, we want to show that institutional change is not only an economic or a political process but fundamentally a cultural one. It is therefore based on a change in values and mentalities. Like in a chemical reaction, we discern initial conditions, factors which triggered the reaction, catalysts and elements of synthesis. Chinese institutional change per se derived from a cultural shock induced by the Chinese economic...

  18. [Key points of poverty alleviation of Chinese herbal medicine industry and classification of recommended Chinese herbal medicines].

    Science.gov (United States)

    Huang, Lu-Qi; Su, Gang-Qiang; Zhang, Xiao-Bo; Sun, Xiao-Ming; Wu, Xiao-Jun; Guo, Lan-Ping; Li, Meng; Wang, Hui; Jing, Zhi-Xian

    2017-11-01

    To build a well-off society in an all-round way, eliminate poverty, improve people's livelihood and improve the level of social and economic development in poverty-stricken areas is the frontier issues of the government and science and technology workers at all levels. Chinese herbal medicine is the strategic resource of the people's livelihood, Chinese herbal medicine cultivation is an important part of China's rural poor population income. As most of the production of Chinese herbal medicine by the biological characteristics of their own and the interaction of natural ecological environment factors, showing a strong regional character.the Ministry of Traditional Chinese Medicine and the State Council Poverty Alleviation Office and other five departments jointly issued the "China Herbal Industry Poverty Alleviation Action Plan (2017-2020)", according to local conditions of guidance and planning of Chinese herbal medicine production practice, promote Chinese herbal medicine industry poverty alleviation related work In this paper, based on the relevant data of poverty-stricken areas, this paper divides the areas with priority to the poverty alleviation conditions of Chinese herbal medicine industry, and analyzes and catalogs the list of Chinese herbal medicines grown in poverty-stricken areas at the macro level. The results show that there are at least 10% of the poor counties in the counties where the poverty-stricken counties and the concentrated areas are concentrated in the poverty-stricken areas. There is already a good base of Chinese herbal medicine industry, which is the key priority area for poverty alleviation of Chinese herbal medicine industry. Poverty-stricken counties, with a certain degree of development of Chinese medicine industry poverty alleviation conditions, the need to strengthen the relevant work to expand the foundation and capacity of Chinese herbal medicine industry poverty alleviation; 37% of poor counties to develop Chinese medicine

  19. Investigating the impact of light and water status on the exchange of COS, 13CO2, CO18O and H218O from bryophytes

    Science.gov (United States)

    Gimeno, Teresa; Royles, Jessica; Ogee, Jerome; Jones, Samuel; Burlett, Regis; West, Jason; Sauze, Joana; Wohl, Steven; Genty, Bernard; Griffiths, Howard; Wingate, Lisa

    2016-04-01

    Terrestrial surfaces are often covered by photoautotrophic communities that play a significant role in the biological fixation of C and N at the global scale. Bryophytes (mosses, liverworts and hornworts) are key members in these communities and are especially adapted to thrive in hostile environments, by growing slowly and surviving repeated dehydration events. Consequently, bryophyte communities can be extremely long-lived (>1500yrs) and can serve as valuable records of historic climate change. In particular the carbon and oxygen isotope compositions of mosses can be used as powerful proxies describing how growing season changes in atmospheric CO2 and rainfall have changed in the distant past over the land surface. Interpreting the climate signals of bryophyte biomass requires a robust understanding of how changes in photosynthetic activity and moisture status regulate the growth and isotopic composition of bryophyte biomass. Thus theoretical models predicting how changes in isotopic enrichment and CO2 discrimination respond to dehydration and rehydration are used to tease apart climatic and isotopic source signals. Testing these models with high resolution datasets obtained from new generation laser spectrometers can provide more information on how these plants that lack stomata cope with water loss. In addition novel tracers such as carbonyl sulfide (COS) can also be measured at high resolution and precision (bryophyte species (Marchantia sp.) in the light and during the dark, through complete desiccation cycles. Our measurements consistently reveal a strong enrichment dynamic in the oxygen isotope composition of transpired water over the dessication cycle that caused an increase in the oxygen isotope discrimination of CO2. These data followed closely values predicted by our process-based model. We also observed a consistent pattern in the fluxes of CO2 and COS during the desiccation cycle. Initially when the bryophyte was wet and a barrier to diffusion existed

  20. Cultural influence, economic security, and the fertility behavior of the Chinese in Canada

    Directory of Open Access Journals (Sweden)

    Zongli Tang

    2001-12-01

    analysis and random coefficient models are the major statistical tools employed to achieve the above objectives. The Chinese-Canadians are compared to the British-Canadians, who are used as the reference group. The findings suggest that Chinese reproductive norms with pronatalist endowments exert strong influence on the fertility behavior of the Chinese in Canada. This influence effectively counteracts the negative effects of economic insecurity and encourages Chinese immigrants to quickly recover their fertility deficit after the initial immigration stage. The effects of the origin culture on fertility diminish with increasing exposure to the host society. However, even among the nativeborn or Canadian-born Chinese, the influence of Chinese reproductive norms is still present though not as strong as among the foreign-born Chinese.

  1. Chinese Foods; Teacher's Handbook.

    Science.gov (United States)

    Huang, Joe, Ed.

    Different styles of Chinese cooking, traditional food items, cooking utensils, serving techniques, and the nutritional value of Chinese cooking are described in this teaching guide. Lesson plans for the preparation of simple dishes are presented. Recipes, a shopping guide to San Francisco's Chinatown, a guide to sources of supplies, and a…

  2. Fabrication of Cost-Effective Dye-Sensitized Solar Cells Using Sheet-Like CoS2 Films and Phthaloylchitosan-Based Gel-Polymer Electrolyte

    Directory of Open Access Journals (Sweden)

    Saradh Prasad

    2018-01-01

    Full Text Available Platinum-free counter electrodes (CE were developed for use in efficient and cost-effective energy conversion devices, such as dye-sensitized solar cells (DSSCs. Electrochemical deposition of CoS2 on fluorine-doped tin oxide (FTO formed a hierarchical sheet-like structured CoS2 thin film. This film was engaged as a cost-effective platinum-free and high-efficiency CE for DSSCs. High stability was achieved using a phthaloychitosan-based gel-polymer electrolyte as the redox electrolyte. The electrocatalytic performance of the sheet-like CoS2 film was analyzed by electrochemical impedance spectroscopy and cyclic voltammetry. The film displayed improved electrocatalytic behavior that can be credited to a low charge-transfer resistance at the CE/electrolyte boundary and improved exchange between triiodide and iodide ions. The fabricated DSSCs with a phthaloychitosan-based gel-polymer electrolyte and sheet-like CoS2 CE had a power conversion efficiency (PCE, η of 7.29% with a fill factor (FF of 0.64, Jsc of 17.51 mA/cm2, and a Voc of 0.65 V, which was analogous to that of Pt CE (η = 7.82%. The high PCE of the sheet-like CoS2 CE arises from the enhanced FF and Jsc, which can be attributed to the abundant active electrocatalytic sites and enhanced interfacial charge-transfer by the well-organized surface structure.

  3. Branding Cities, Changing Societies

    DEFF Research Database (Denmark)

    Ooi, Can-Seng

    Societal changes are seldom discussed in the literature on city branding. The time element is important because it highlights the fluctuating reality of society. The city brand message freezes the place but in fact, the city branding exercise is a continuous process. Society emerges too. City...... brands are supposed to accentuate the uniqueness of the city, be built from the bottom-up and reflect the city's identity. This paper highlights three paradoxes, pointing out that city branding processes can also make cities more alike, bring about societal changes and forge new city identities. A city...... branding campaign does not just present the city, it may change the city. The relationships between the branding exercise and the city are intertwined in the evolution of the place....

  4. Connecting Science with Society

    DEFF Research Database (Denmark)

    awareness of the important questions of our society reflected in scientific research and of the answers produced by these research activities. The CRIS2010 conference, entitled “Bringing Science to Society”, therefore seeks to highlight the role of Current Research Information Systems for communicating......CRIS2010, the 10th conference in the bi-annual series organized by euroCRIS, focuses on the connecting role of Current Research Information Systems (CRIS). Aalborg, Denmark where CRIS2010 is held, is located near the intersection of the Northern Sea and Kattegat, a place were not only the waters...... of two seas are exchanged, but also goods and culture. In a similar way, Current Research Information Systems are at the intersection between (publicly funded) research and society. They do not only connect actors, activities and results within the research domain but also play a crucial role in raising...

  5. Branding Cities, Changing Societies

    DEFF Research Database (Denmark)

    Ooi, Can-Seng

    brands are supposed to accentuate the uniqueness of the city, be built from the bottom-up and reflect the city's identity. This paper highlights three paradoxes, pointing out that city branding processes can also make cities more alike, bring about societal changes and forge new city identities. A city......Societal changes are seldom discussed in the literature on city branding. The time element is important because it highlights the fluctuating reality of society. The city brand message freezes the place but in fact, the city branding exercise is a continuous process. Society emerges too. City...... branding campaign does not just present the city, it may change the city. The relationships between the branding exercise and the city are intertwined in the evolution of the place....

  6. Discrimination in Modern Society

    OpenAIRE

    Schekach, E. V.; Щекач, Е. В.

    2013-01-01

    Issues of discrimination in modern society are examined in the article. Types of discrimination, ways of demonstration, methods of combating discrimination and inequality are described. Particular attention is paid to the legal basis and the real life stories, which serve as a material base for judgments how to prevent discrimination. Possible ways are suggested to eliminate such a negative phenomenon of society like discrimination. Статья посвящена вопросам дискриминации в современном общ...

  7. Chinese Companies in Switzerland

    Directory of Open Access Journals (Sweden)

    Esther Kessler

    2014-10-01

    Full Text Available In recent years, some of China’s leading firms have made headlines with their European expansion, by either opening new facilities or by acquiring or merging with significant enterprises in Europe. The goal of this paper is to contribute to the existing literature by examining Chinese enterprises expanding into Switzerland. The study also allows some conclusions for Chinese companies entering Central and Eastern Europe. We analyze via interviews the motivations of Chinese companies to expand into Switzerland as well as their behavior and the impediments in their internationalization process. Our findings show that Chinese companies fail to take advantage of certain benefits of western economies (such as open information and stable rule of law. To move forward efficiently, they should develop competence in dealing systematically with readily available market information, building professional networks that recognize a separation between business life and personal life, and managing their Chinese and foreign employees in the foreign cultural environment.

  8. Society and Social Power

    Directory of Open Access Journals (Sweden)

    Janani Harish

    2014-10-01

    Full Text Available Society is the source of immense power. Over the past few centuries humanity has record­ed phenomenal growth in its collective capacity for accomplishment, as reflected in the 12-fold growth in global per capita income since 1800. The remarkable achievements in living standards, longevity, science, technology, industry, education, democracy, human rights, peace and global governance are the result of the exponential development of the capacity of society to harness human energies and convert them into social power for productive purposes. Today, humanity possesses the power and capabilities needed to fully meet the multi-dimensional challenges confronting global society. The source of this energy is people. Human energy is transformed into social power by the increasing reach, frequency and complexity of human relationships. Society is a complex living network of organized relationships between people. Its power issues from channelizing our collective energies in productive ways by means of organizing principles such as coordination, systems, specialization of function, hierarchy of authority, and integration. This immense social power remains largely underutilized. Social science needs to evolve a comprehensive, trans-disciplinary understanding of the roots of social power and the process by which it is generated, distributed and applied. This knowledge is the essential foundation for formulating effective social policies capable of eradicating forever persistent poverty, unemployment and social inequality. This article is based on a series of lectures delivered by the author in the WAAS-WUC course on “Toward a Trans-disciplinary Science of Society” at Dubrovnik on September 1-3, 2014. It traces the development of social power in different fields to show that human and social capital are inexhaustible in potential. The more we harness them, the more they grow. Unleashing, directing, channeling and converting human potential into social

  9. Evolution, museums and society.

    Science.gov (United States)

    MacFadden, Bruce J

    2008-11-01

    Visitors to natural history museums have an incomplete understanding of evolution. Although they are relatively knowledgeable about fossils and geological time, they have a poor understanding of natural selection. Museums in the 21st century can effectively increase public understanding of evolution through interactive displays, novel content (e.g. genomics), engaging videos and cyberexhibits that communicate to a broad spectrum of society, both within the exhibit halls as well as outside the museum.

  10. Creativity In Conscience Society

    OpenAIRE

    Ion Gh. Rosca; Dumitru Todoroi

    2011-01-01

    Creativity is a result of brain activity which differentiates individuals and could ensure an important competitive advantage for persons, for companies, and for Society in general. Very innovative branches – like software industry, computer industry, car industry – consider creativity as the key of business success. Natural Intelligence Creativity can develop basic creative activities, but Artificial Intelligence Creativity, and, especially, Conscience Intelligence Creativity should be devel...

  11. The new totalitarian society

    Directory of Open Access Journals (Sweden)

    Vlajki Emil

    2011-01-01

    Full Text Available The new totalitarian society is a euphemized expression denoting the New World Order, which in itself denotes the American globalization. The underpinning of this mindset is rationality, which is characteristic of Western civilization. Christianity engendered rationality by introducing it through St. Thomas Aquinas, Aristotle, and especially formal logic. Since it is obvious that religion and logic cannot ultimately be harmonized, this combination has proven lethal in many cases throughout history. For instance, the Inquisition, which, contrary to what happened at scholastic universities, severely berated rational thinking in practice. Catholicism helped carry out genocide against the Jews, and Orthodoxy is in a certain manner tied in with Stalinism. The new totalitarian society is anchored in American Protestantism. On the whole, Christian rationalism is a sphere of science, techniques and technologies efficiently employed to promote the West to the status of a society of plenty and the conception of human rights, which turn into their opposite and irrational behavior of the worst kind. An example of such inhumanity is the attack against Yugoslavia/Serbia in 1999.

  12. Translation: an example from ancient Chinese to modern Chinese

    NARCIS (Netherlands)

    Liu, X; Hoede, C.

    2002-01-01

    In this paper, we gave an idea of translation by means of knowledge graph theory from ancient Chinese to modern Chinese, by using an example story. Actually, we give the details of the method of translation from ancient Chinese to modern Chinese step by step as carried out by hand. From the example,

  13. Cognitive and Social Influences on Gang Involvement among Delinquents in Three Chinese Cities

    Science.gov (United States)

    Ngai, Ngan-pun; Cheung, Chau-kiu; Ngai, Steven Sek-Yum

    2007-01-01

    Inasmuch as research has held the increase in youth gang activities responsible for the escalating level of crime and delinquency in Chinese societies, ascertaining risk or protective factors of gang involvement among Chinese youths is crucial. The factors include those associated with social control, social learning, and cognitive development. To…

  14. Students Learn about Chinese Culture through the Folktale "Yeh-Shen": Emphasizing Figurative Language Interpretation

    Science.gov (United States)

    Palmer, Barbara C.; Sun, Lingzhi; Leclere, Judith T.

    2012-01-01

    This article will analyze the figurative language that reflects Chinese traditional society and culture in "Yeh-Shen." The authors will consider both the figures of speech and the figures of thought (to include symbolism) that provide insight into an understanding of the Chinese culture through a reading of "Yeh-Shen." This analysis can be used by…

  15. The Chinese negotiation.

    Science.gov (United States)

    Graham, John L; Lam, N Mark

    2003-10-01

    Most Westerners preparing for a business trip to China like to arm themselves with a list of etiquette how-tos. "Carry a boatload of business cards," tipsters say. "Bring your own interpreter." "Speak in short sentences." "Wear a conservative suit." Such advice can help get companies in the door and even through the first series of business transactions. But it won't sustain the prolonged, year-in, year-out associations Chinese and Western businesses can now achieve. The authors' work with dozens of companies and thousands of American and Chinese executives over the past 20 years has demonstrated that a superficial adherence to etiquette rules gets executives only so far. They have witnessed communication breakdowns between American and Chinese businesspeople time and time again. The root cause: the American side's failure to understand the much broader context of Chinese culture and values, a problem that too often leaves Western negotiators flummoxed and flailing. American and Chinese approaches often appear incompatible. Americans see Chinese negotiators as inefficient, indirect, and even dishonest, while the Chinese see American negotiators as aggressive, impersonal, and excitable. Such perceptions have deep cultural origins. Yet those who know how to navigate these differences can develop thriving, mutually profitable, and satisfying business relationships. Four cultural threads have bound the Chinese people together for some 5,000 years, and these show through in Chinese business negotiations. They are agrarianism, morality, the Chinese pictographic language, and wariness of strangers. Most Western businesspeople often find those elements mysterious and confusing. But ignore them at any time during the negotiation process, and the deal can easily fall apart.

  16. The Chinese Tiger Mother

    Directory of Open Access Journals (Sweden)

    Jacek Hołówka

    2011-12-01

    Full Text Available In 2010 a book by Amy Chua: Battle Hymn of the Tiger Mother was published and it sparked a broad discussion among pedagogues and the open society about the factors determining educational success. Chua forms a simple and provocative thesis – the Chinese mothers are the best in the world because they don’t spoil their children, quickly introduce them into the adult culture, have high expectations of them, they are brusque and cold but they teach their children how to survive and be competitive. Chua shows this educational model as a contrast to the Western model, where the children have their own, naive and sentimental culture, their own shops and catwalks in shopping malls. The results of systematic research on education seem to prove something quite different. The educational success has to be measured using different scales, because it depends on different factors. The data published by OECD show that the level of education depends on the educational tradition of the society, level of GDP, intergenerational contacts, level of education of teachers and their social status. A strong determiner is the family, but not necessarily the mother. Even more, there is a strong correlation between the results in learning and a supporting stance of the parents, but also with their habit of spending free time with their children. The parents who take their children to the cinema, an a trip, gossip with them or take them to McDonalds, can be sure that their children will have statistically higher than the average grades. Detailed results from other sources show that success correlates the most with grades from previous class, parents’ habit of talking about things at school, higher education of the parents, being a child of a single mother, signing the child up for extracurricular classes from music and the mother working part-time. Failure correlates with being an Afro-American or Latino, checking homework by parents, free time after school without

  17. Chinese nuclear insurance and Chinese nuclear insurance pool

    International Nuclear Information System (INIS)

    Gong Zhiqi

    2000-01-01

    Chinese Nuclear Insurance Started with Daya Bay Nuclear Power Station, PICC issued the insurance policy. Nuclear insurance cooperation between Chinese and international pool's organizations was set up in 1989. In 1996, the Chinese Nuclear Insurance Pool was prepared. The Chinese Nuclear Insurance Pool was approved by The Chinese Insurance Regulatory Committee in May of 1999. The principal aim is to centralize maximum the insurance capacity for nuclear insurance from local individual insurers and to strengthen the reinsurance relations with international insurance pools so as to provide the high quality insurance service for Chinese nuclear industry. The Member Company of Chinese Nuclear Pool and its roles are introduced in this article

  18. Proceedings of the PILAC optics workshop

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    This report contains viewgraphs on the following topics: PILAC Overview; PILAC Injection Line; PILAC General-Purpose Line Design; Program RAYTRACE; Design & Performance of MRS; Program MOTER; Recent Upgrades of MOTER; Use of MOTER at Michigan State; Spectrometer Design at Michigan State; Use of MOTER at CEBAF & Related Topics; TOSCA Calculations at CEBAF; TOSCA Calculations for PILAC; Measurements of EPICS Quadrupoles; Quadrupole Measurements and Analysis at Bates Laboratory; Analysis of 3D Quadrupole Data; Quadrupole 3D Fringe Fields (Theoretical Lecture); Analysis of 3D Field Data; Analysis of Dipole Fringe Fields; Quadrupoles with Perfect N=2 Symmetry; CEBAF Superconducting Cos (20) Quadrupole; Upgrades to TRANSPORT and TURTLE; Optics using Differential Algebra; and A Possible Test of Quad Optics Using EPICS.

  19. Flatland optics. III. Achromatic diffraction.

    Science.gov (United States)

    Lohmann, A W; Pe'er, A; Wang, D; Friesem, A A

    2001-09-01

    In the previous two sections of "Flatland optics" [J. Opt. Soc. Am. A 17, 1755 (2000); 18, 1056 (2001)] we described the basic principles of two-dimensional (2D) optics and showed that a wavelength lambda in three-dimensional (3D) space (x, y, z) may appear in Flatland (x, z) as a wave with another wavelength Lambda=lambda/cos alpha. The tilt angle alpha can be modified by a 3D-Spaceland individual, who then is able to influence the 2D optics in a way that must appear to be magical to 2D-Flatland individuals-in the spirit of E. A. Abbott's science fiction story of 1884 [Flatland, a Romance of Many Dimensions, 6th ed. (Dover, New York, 1952)]. Here we show how the light from a white source can be perceived in Flatland as perfectly monochromatic, so diffraction with white light will be free of color blurring and the contrast of interference fringes can be 100%. The basic considerations for perfectly achromatic diffraction are presented, along with experimental illustration of Talbot self-imaging performed with broadband illumination.

  20. Science, Society and Policy

    Science.gov (United States)

    White, K. S.; Teich, A. H.

    2010-12-01

    Apart from the journals they produce, scientific societies play an important role in communicating scientific findings and norms to the broader society. The American Association for the Advancement of Science (AAAS) includes among its goals to promote and defend the integrity of science and its use; provide a voice for science on societal issues; promote the responsible use of science in public policy; and increase public engagement with science and technology. AAAS websites and programs, including Communicating Science (www.aaas.org/communicatingscience), Working with Congress (http://www.aaas.org/spp/cstc/wwc/book.htm) and ScienceCareers.org (http://sciencecareers.sciencemag.org), provide tools for scientists to become more directly engaged in effectively communicating their findings and involved in the policy process. Education programs work to build the next generation of scientists and a science-literate public. To bridge the current communication gap between scientists, the public and policymakers, AAAS, like other scientific societies, maintains policy and outreach programs with limited budgets and staff. AAAS works to engage policymakers and provide scientific underpinning to key issues through congressional briefings, meetings, policy briefs, and media outreach. AAAS responds to challenges to accepted scientific findings and processes through op-eds, letters to government officials, resolutions, and Board statements. Some of these initiatives occur on a local level in partnership with local civic leaders, whose endorsement makes them more powerful. On a national scale, they assure that the voice of science is included in the debate. The changing media landscape presents opportunities and challenges for future AAAS endeavors.

  1. Risk and society

    International Nuclear Information System (INIS)

    Tubiana, M.; Vrousos, C.; Pages, J.P.; Carde, C.

    1999-01-01

    This book brings together the communications presented at the colloquium 'risk and society' held in Paris (France) on November 1998. During this colloquium, the various aspects of risk and of its management were discussed by medical specialists, historians, industrialists, engineers, philosophers, lawyers, politicians and administration representatives. The first theme concerns the controversies generated by the development of some activities (genetics, bio-technologies, nuclear and radiations use). The second theme concerns the management of risks and the way to conciliate the point of view of authorities and citizens (confidence of the public with respect to experts, scientists, industrialists, government and administrative representatives, role played by the media). The debates that took place during the colloquium have shown that the public opinion concerning the nuclear activities or the new technologies greatly depends on the ideological attitudes and on the public's likes and dislikes with respect to some categories of actors (distrust with respect to public decisions, fears with respect to changes and future, nostalgia of the past). The following aspects are reviewed: Notions of risk and hazard (risk and health, risk in today's society, medicine and society, the point of view of the industrialists and of the scientific and technical specialists); from the psychological aspects of the risk to its social aspects (survey of the risk assessment battlefield, social attenuation and amplification of risk, the feeling of risks in Europe, insecurity and delinquency, controversies around radioactivity and health); the negotiation and communication about risks (risk and public health, negotiation around risks, risks and information dissemination about the public debate, communication and crisis, evolution of risk communication, comparison between American and European approaches, the Seveso directive); the public debate and the evolution of risks management (the

  2. Application of Toxic Chinese Medicine in Chinese Pharmacopoeia

    Science.gov (United States)

    Zhao, Hui; Feng, Yu; Mao, Mingsan

    2018-01-01

    Objective: Explore the application characteristics of proprietary Chinese medicine prescriptions containing toxic herbs in pharmacopoeia. Methods: In this paper, according to the clinical application of pharmacopoeia proprietary Chinese medicine is divided into table agent, Qushu agent, diarrhea agent, heat agent, Wen Li agent, cough and asthma agents, resuscitation agent, Gutian agent, Fuzheng agent, Anshen agent, hemostatic agent, The traditional Chinese medicine prescription and the clinical application of the Chinese herbal medicine containing the toxic Chinese medicine were analyzed and sorted out., Summed up the compatibility of toxic herbs and application characteristics. Results: Toxic Chinese herbal medicine in the cure of traditional Chinese medicine to play a long-standing role, through the overall thinking, dialectical thinking, and thinking of toxic Chinese medicine in the analysis of Chinese medicine that [2], toxic Chinese medicine in the application of proprietary Chinese medicine can not lack. Conclusion: Pharmacopoeia included proprietary Chinese medicine not only in the clinical treatment of good, but also the application of its toxic traditional Chinese medicine and its understanding of the enrichment of the toxic characteristics of traditional Chinese medicine and treatment-related disease pathology between the points of contact for patients with clinical applications Based on and theoretical guidance of Chinese medicine [3].

  3. Popular Music and Society

    DEFF Research Database (Denmark)

    2007-01-01

    Fifteen years after the collapse of the Soviet Union, popular music is thriving in the former Soviet territories and covers a broad variety of genres.  Among these are rock bands formed in the Soviet era, surviving legends of Soviet pop, and younger bands and performers of the 1990s and 2000s...... or the Russkii Rok-Klub v Amerike (Russian Rock Club of America).   This special edition of Popular Music and Society aims to present research on contemporary popular music (broadly defined) in the former Soviet republics and their diasporas.  A central issue will be how the musical landscape has changed since...

  4. Membership in cooperative societies

    Directory of Open Access Journals (Sweden)

    Eba Gaminde Egia

    2017-12-01

    Full Text Available In this work we will analyze the practical application of one of the cooperative principles, «voluntary and free membership», referring to the entering of members in cooperative societies. We will first explain the meaning of this principle, and then bring up its normative regulation, with special emphasis on those aspects in which our autonomic laws differ, and ending with a brief reference to the economic aspect and the different ways to make contributions and their consequences.Received: 31 May 2017Accepted: 14 October 2017Published online: 22 December 2017

  5. Performing "Chinese-ness" in Singkawang

    NARCIS (Netherlands)

    Ong, C.E.; Ormond, M.E.; Sulianti, Dian

    2017-01-01

    Through an examination of two festivals – Qing Ming and Cap Go Meh – in the town of Singkawang in Indonesian Borneo (Kalimantan), we show how Singkawang-bound Chinese Indonesian tourists and their Singkawang-based relatives produce a diasporic heritage network through ‘moorings’ generated by both

  6. Fibre-optical microendoscopy.

    Science.gov (United States)

    Gu, M; Bao, H; Kang, H

    2014-04-01

    Microendoscopy has been an essential tool in exploring micro/nano mechanisms in vivo due to high-quality imaging performance, compact size and flexible movement. The investigations into optical fibres, micro-scanners and miniature lens have boosted efficiencies of remote light delivery to sample site and signal collection. Given the light interaction with materials in the fluorescence imaging regime, this paper reviews two classes of compact microendoscopy based on a single fibre: linear optical microendoscopy and nonlinear optical microendoscopy. Due to the fact that fluorescence occurs only in the focal volume, nonlinear optical microendoscopy can provide stronger optical sectioning ability than linear optical microendoscopy, and is a good candidate for deep tissue imaging. Moreover, one-photon excited fluorescence microendoscopy as the linear optical microendoscopy suffers from severe photobleaching owing to the linear dependence of photobleaching rate on excitation laser power. On the contrary, nonlinear optical microendoscopy, including two-photon excited fluorescence microendoscopy and second harmonic generation microendoscopy, has the capability to minimize or avoid the photobleaching effect at a high excitation power and generate high image contrast. The combination of various nonlinear signals gained by the nonlinear optical microendoscopy provides a comprehensive insight into biophenomena in internal organs. Fibre-optical microendoscopy overcomes physical limitations of traditional microscopy and opens up a new path to achieve early cancer diagnosis and microsurgery in a minimally invasive and localized manner. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

  7. Optical Coherence Tomographic and Visual Results at Six Months after Transitioning to Aflibercept for Patients on Prior Ranibizumab or Bevacizumab Treatment for Exudative Age-Related Macular Degeneration (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Chan, Clement K.; Jain, Atul; Sadda, Srinivas; Varshney, Neeta

    2014-01-01

    Purpose: To study optical coherence tomographic (OCT) results and vision at 6 months after transition (post-Tx) from intravitreal bevacizumab and/or ranibizumab to aflibercept for treatment of neovascular age-related macular degeneration (nAMD). The null hypothesis was the lack of improvements in OCT metrics and vision outcome in study eyes at 6 months after transitioning from bevacizumab or ranibizumab to aflibercept. Methods: This retrospective study assessed 6 monthly OCT (Cirrus) data after transitioning to aflibercept for eyes on prior Legacy-ranibizumab, Legacy-bevacizumab, or mixed treatment for nAMD. Outcome measures were subretinal fluid (SRF), cystoid macular edema (CME), pigment epithelial detachment (PED) heights and volumes, central 1- and 3-mm subfield, Macular Volume, and best spectacle and pinhole visual acuity (VA). A single masked investigator performed all OCT measurements. Results: One hundred eighty-nine eyes in 172 patients in Legacy-bevacizumab (95 eyes), Legacy-ranibizumab (84 eyes), or Mixed Group(10 eyes) were switched to aflibercept and followed for 6 months. Significant post-Tx reductions were noted in SRF/CME heights and volumes (all P<.001). Similar findings were noted for PED heights (122.8 μm vs 79.4 μm) and PED volumes (all P<.001). Post-Tx VA was better (20/43 vs 20/51, P<.001). There were no differences between Legacy-bevacizumab and Legacy-ranibizumab groups in OCT and VA changes. Post-Tx VA, SRF/CME, and PED heights and volumes were improved for Nonresponders (suboptimal response to bevacizumab/ranibizumab) (P=.001 to <.001), but not Responders (good responses to same). The only adverse event was a retinal pigment epithelial tear in one eye. Conclusions: Significant improvements in vision and OCT metrics developed in Nonresponders but not in Responders. Post-Tx VA and OCT measures were similar for eyes on prior bevacizumab or ranibizumab. Post-Tx adverse events were uncommon. PMID:25646034

  8. Molecular cooking: Physical transformations in Chinese ‘century’ eggs

    NARCIS (Netherlands)

    Eiser, E.; Miles, C.S.; Geerts, N.; Verschuren, P.; MacPhee, C.E.

    2009-01-01

    Over two thousand years ago the Chinese developed a method to preserve eggs such that they remain edible for many months. The room temperature, physico-chemical preservation process that is used to prepare ‘century’ eggs transforms the egg white into a yellow, transparent gel with optical and

  9. Conceptualizing the Cultural and Political Facets of “Chinese Nationalism” in an Era of China’s Global Rise

    DEFF Research Database (Denmark)

    Bislev, Ane Katrine; Li, Xing

    2014-01-01

    Understanding Chinese nationalism and national identity is of primary importance in comprehending the increasingly assertive role that a rising China plays on the global political scene. But “Chinese nationalism” is a very difficult concept to deal with due to differences in the Western and Chinese...... society is also recognized by the Chinese state, that deliberately fosters patriotic sentiment among the young generation through the Patriotic Education Campaign. Material from this campaign is used to provide an important indication of the patriotic content of current Chinese state nationalism....

  10. Changes in Chinese hair growth along a full year.

    Science.gov (United States)

    Liu, C; Yang, J; Qu, L; Gu, M; Liu, Y; Gao, J; Collaudin, C; Loussouarn, G

    2014-12-01

    To confirm the existence of seasonal hair growth cycle among Chinese subjects and objectivize the seasonal effect of hair loss; the hair growth parameters of Chinese volunteers were followed monthly for an entire year on the same area of vertex. The hair growth parameters of 41 Chinese volunteers (women and men), free from alopecia, were recorded monthly along an entire year using the phototrichogram technique. Results show an increased rate of telogen hairs (growing arrest) around August-September in the study group, as previously reported in European subjects albeit of a lower extent and remaining within the normal range of healthy head hair parameters. The possible effects of latitude and daylight duration are discussed. Data confirm that Chinese hairs present characteristics of the most developed and fast growing terminal fibres, as compared to other non-Asian ethnics. © 2014 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  11. Communicating Science to Society

    Science.gov (United States)

    Illingworth, Samuel; Muller, Jennifer; Leather, Kimberley; Morgan, William; O'Meara, Simon; Topping, David; Booth, Alastair; Llyod, Gary; Young, Dominique; Bannan, Thomas; Simpson, Emma; Percival, Carl; Allen, Grant; Clark, Elaine; Muller, Catherine; Graves, Rosemarie

    2014-05-01

    "Nothing in science has any value to society if it is not communicated." So goes the 1952 quote from Anne Roe, the noted twentieth century American psychologist and writer. She went on to say that "scientists are beginning to learn their social obligations", and now over 60 years later there is certainly evidence to support her assertions. As scientists, by communicating our research to the general public we not only better inform the tax payer where their money is being spent, but are also able to help put into context the topical environmental challenges and issues that society faces, as well as inspiring a whole new generation of future scientists. This process of communication is very much a two-way street; by presenting our work to people outside of our usual spheres of contemporaries, we expose ourselves to alternative thoughts and insights that can inspire us, as scientists, to take another look at our research from angles that we had never before considered. This work presents the results and experiences from a number of public engagement and outreach activities across the UK, in which geoscientists engaged and interacted with members of the general public. These include the design and implementation of Raspberry Pi based outreach activities for several hundred high school students; the process of running a successful podcast (http://thebarometer.podbean.com); hosting and participating in science events for thousands of members of the general public (e.g. http://www.manchestersciencefestival.com and http://sse.royalsociety.org/2013); and creating a citizen science activity that involved primary school children from across the UK. In communicating their research it is imperative that scientists interact with their audience in an effective and engaging manner, whether in an international conference, a classroom, or indeed down the pub. This work also presents a discussion of how these skills can be developed at an early stage in the careers of a research

  12. Nanotechnology and society

    Science.gov (United States)

    Keller, Kenneth H.

    2007-01-01

    Past experience has shown that the successful introduction of a new technology requires careful attention to the interactions between the technology and society. These interactions are bi-directional: on the one hand, technology changes and challenges social patterns and, on the other hand, the governance structures and values of the society affect progress in developing the technology. Nanotechnology is likely to be particularly affected by these kinds of interactions because of its great promise and the unusually early public attention it has received. Moreover, it represents a new kind of experiment in packaging a rather wide range of fundamental research activities under a single "mission-like" umbrella. Although this gives it more impetus as a field, it sets a higher bar for showing successful applications early on and because it links disparate fields, regulatory regimes reasonable for one kind of nanotechnology development may be inappropriately extended to others. There are a number of lessons to be gleaned from experience with the introduction of other technologies, which offer guidance with respect to what pitfalls to avoid and what issues to be sensitive to as we move forward with the development of nanotechnology applications. The problems encountered by nuclear power point out the dangers of over-promising and the role the need for the technology plays in ameliorating fears of risk. The public reaction to biomedical engineering and biotechnology highlights, in addition, the cultural factors that come into play when technologies raise questions about what is "natural" and what is "foreign" and what conceptions are involved in defining "personhood". In all cases, it has been clear that a main task for those introducing new technology is building public trust-in the safety of the technologies and the integrity of those introducing it. The advocates of nanotechnology have already shown that they are generally aware of the need to consider the public

  13. Nanotechnology and society

    International Nuclear Information System (INIS)

    Keller, Kenneth H.

    2007-01-01

    Past experience has shown that the successful introduction of a new technology requires careful attention to the interactions between the technology and society. These interactions are bi-directional: on the one hand, technology changes and challenges social patterns and, on the other hand, the governance structures and values of the society affect progress in developing the technology. Nanotechnology is likely to be particularly affected by these kinds of interactions because of its great promise and the unusually early public attention it has received. Moreover, it represents a new kind of experiment in packaging a rather wide range of fundamental research activities under a single 'mission-like' umbrella. Although this gives it more impetus as a field, it sets a higher bar for showing successful applications early on and because it links disparate fields, regulatory regimes reasonable for one kind of nanotechnology development may be inappropriately extended to others. There are a number of lessons to be gleaned from experience with the introduction of other technologies, which offer guidance with respect to what pitfalls to avoid and what issues to be sensitive to as we move forward with the development of nanotechnology applications. The problems encountered by nuclear power point out the dangers of over-promising and the role the need for the technology plays in ameliorating fears of risk. The public reaction to biomedical engineering and biotechnology highlights, in addition, the cultural factors that come into play when technologies raise questions about what is 'natural' and what is 'foreign' and what conceptions are involved in defining 'personhood'. In all cases, it has been clear that a main task for those introducing new technology is building public trust-in the safety of the technologies and the integrity of those introducing it. The advocates of nanotechnology have already shown that they are generally aware of the need to consider the public

  14. Traditional Chinese Biotechnology

    Science.gov (United States)

    Xu, Yan; Wang, Dong; Fan, Wen Lai; Mu, Xiao Qing; Chen, Jian

    The earliest industrial biotechnology originated in ancient China and developed into a vibrant industry in traditional Chinese liquor, rice wine, soy sauce, and vinegar. It is now a significant component of the Chinese economy valued annually at about 150 billion RMB. Although the production methods had existed and remained basically unchanged for centuries, modern developments in biotechnology and related fields in the last decades have greatly impacted on these industries and led to numerous technological innovations. In this chapter, the main biochemical processes and related technological innovations in traditional Chinese biotechnology are illustrated with recent advances in functional microbiology, microbial ecology, solid-state fermentation, enzymology, chemistry of impact flavor compounds, and improvements made to relevant traditional industrial facilities. Recent biotechnological advances in making Chinese liquor, rice wine, soy sauce, and vinegar are reviewed.

  15. Chinese Studies and Beyond

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    2013-01-01

    Many different conceptual approaches and models have been used to analyze contemporary Chinese history and politics. Some of the more commonly used include "totalitarianism", "two-line struggle", "clientelism", "tendency analysis", "political culture", "interest group politics", "bureaucratic...

  16. Chinese implicit leadership theory.

    Science.gov (United States)

    Ling, W; Chia, R C; Fang, L

    2000-12-01

    In a 1st attempt to identify an implicit theory of leadership among Chinese people, the authors developed the Chinese Implicit Leadership Scale (CILS) in Study 1. In Study 2, they administered the CILS to 622 Chinese participants from 5 occupation groups, to explore differences in perceptions of leadership. Factor analysis yielded 4 factors of leadership: Personal Morality, Goal Efficiency, Interpersonal Competence, and Versatility. Social groups differing in age, gender, education level, and occupation rated these factors. Results showed no significant gender differences, and the underlying cause for social group differences was education level. All groups gave the highest ratings to Interpersonal Competence, reflecting the enormous importance of this factor, which is consistent with Chinese collectivist values.

  17. Chinese Musical Prodigies.

    Science.gov (United States)

    Kwok, Carolyn; Harris, R. Carl

    1989-01-01

    The article describes several young Chinese musical prodigies as well as principles of the Shanghai Music Conservatory's middle and primary schools which provide intensive musical training to musically gifted students. (DB)

  18. Behaviorism and Society.

    Science.gov (United States)

    Krapfl, Jon E

    2016-05-01

    A probable list of causes for the limited acceptance of behaviorism in our society is identified. This is followed by a summary review of the proposed solutions identified in other papers in this special issue of The Behavior Analyst, most of which relate to either better marketing of either the behavior analytic process or the results achieved as a consequence. One paper proposes a more broad conception of behavior analysis. This paper endorses the solutions identified in previous papers and then goes on to propose an even more broad conception of behavior analysis and makes the point that behavior analysis is unlikely to flourish unless behavior analysts understand a good deal more about the cultural and other contextual features of the environments in which they work.

  19. War and society

    Directory of Open Access Journals (Sweden)

    Upeniece V.

    2016-01-01

    Full Text Available A discussion of effects of war on society is desirable as it can stimulate nations and their politicians to refrain in their international and non-international relations from the threat or use of force against the territorial integrity or political independence of the state. The prohibition of the use of force is a valid norm of customary international law and is fixed in the Charter of the United Nations. Any specific use of force can be lawful only if it is based on exceptions of this rule (action of self-defence under the Article 51 or action under specific authorization by the Security Council under Chapter VII. However the main issue is how to ensure that the other states respect this principle of non-use of force.

  20. Making Sense for Society

    Science.gov (United States)

    van der Heide, J. J.; Grus, M. M.; Nouwens, J. C. A. J.

    2017-09-01

    The Netherlands is a densely populated country. Cities in the metropolitan area (Randstad) will be growing at a fast pace in the coming decades1. Cities like Amsterdam and Rotterdam are being overrun by tourists. Climate change effects are noticed in cities (heavy rains for instance). Call for circular economy rises. Traffic increases. People are more self-reliant. Public space is shared by many functions. These challenges call for smart answers, more specific and directly than ever before. Sensor data is a cornerstone of these answers. In this paper we'll discuss the approaches of Dutch initiatives using sensor data as the new language to live a happy life in our cities. Those initiatives have been bundled in a knowledge platform called "Making sense for society" 1 https://www.cbs.nl/nl-nl/nieuws/2016/37/pbl-cbs-prognose-groei-steden-zet-door (in dutch)

  1. Advanced information society(5)

    Science.gov (United States)

    Tanizawa, Ippei

    Based on the advancement of information network technology information communication forms informationalized society giving significant impact on business activities and life style in it. The information network has been backed up technologically by development of computer technology and has got great contribution by enhanced computer technology and communication equipments. Information is transferred by digital and analog methods. Technical development which has brought out multifunctioned modems of communication equipments in analog mode, and construction of advanced information communication network which has come out by joint work of computer and communication under digital technique, are described. The trend in institutional matter and standardization of electrical communication is also described showing some examples of value-added network (VAN).

  2. Popular Music and Society

    DEFF Research Database (Denmark)

    2007-01-01

    Fifteen years after the collapse of the Soviet Union, popular music is thriving in the former Soviet territories and covers a broad variety of genres.  Among these are rock bands formed in the Soviet era, surviving legends of Soviet pop, and younger bands and performers of the 1990s and 2000s.......   Local and foreign musics blend as new impulses arrive from without and arise from within the region.  Thanks to the most recent wave of Russian emigrants, these popular musics have also spread to various localities around the world, as exemplified by the phenomenon of "Russendisko" in Berlin...... or the Russkii Rok-Klub v Amerike (Russian Rock Club of America).   This special edition of Popular Music and Society aims to present research on contemporary popular music (broadly defined) in the former Soviet republics and their diasporas.  A central issue will be how the musical landscape has changed since...

  3. Nuclear Research and Society

    International Nuclear Information System (INIS)

    Eggermont, G.

    2000-01-01

    In 1998, SCK-CEN took the initiative to include social sciences and humanities into its research programme. Within this context, four projects were defined, respectively on sustainability and nuclear development; transgenerational ethics related to the disposal of long-lived radioactive waste; legal aspects and liability; emergency communication and risk perception. Two reflection groups were established, on expert culture and ethical choices respectively, in order to deepen insight while creating exchange of disciplinary approaches of the committed SCK-CEN researchers and social scientists. Within the context of SCK-CEN's social sciences and humanities programme, collaborations with various universities were initiated, teams consisting of young doctorate and post-doctorate researchers and university promotors with experience in interaction processes of technology with society were established and steering committees with actors and external experts were set up for each project. The objectives and main achievements in the four projects are summarised

  4. Afghanistan, state and society

    DEFF Research Database (Denmark)

    Kværnø, Ole

    In June 2007, the RAND Corporation and the Royal Danish Defence College hosted a conference titled “Afghanistan: State and Society, Great Power Politics, and the Way Ahead”. The two-day event, held in Copenhagen, was attended by more than 100 politicians, scholars, academics, and representative...... of both governmental and nongovernmental institutions from more than 20 states. Its theme was to discuss the problems that Afghanistan faces in the wake of the U.S.-led attack on al Qaeda training camps and the Taliban government; examine the challenges confronting the NATO International Security...... Assistance Force as it coordinates nation-building activities in Afghanistan; and suggest ways to address these issues. This volume compiles 11 of the papers presented at the conference; themes include the importance of historical precedents, coordination among relevant parties, and the development of an all...

  5. Nuclear Research and Society

    Energy Technology Data Exchange (ETDEWEB)

    Eggermont, G

    2000-07-01

    In 1998, SCK-CEN took the initiative to include social sciences and humanities into its research programme. Within this context, four projects were defined, respectively on sustainability and nuclear development; transgenerational ethics related to the disposal of long-lived radioactive waste; legal aspects and liability; emergency communication and risk perception. Two reflection groups were established, on expert culture and ethical choices respectively, in order to deepen insight while creating exchange of disciplinary approaches of the committed SCK-CEN researchers and social scientists. Within the context of SCK-CEN's social sciences and humanities programme, collaborations with various universities were initiated, teams consisting of young doctorate and post-doctorate researchers and university promotors with experience in interaction processes of technology with society were established and steering committees with actors and external experts were set up for each project. The objectives and main achievements in the four projects are summarised.

  6. Expectations from Society

    International Nuclear Information System (INIS)

    Blowers, A.

    2008-01-01

    Prof. A. Blowers observed that the social context within which radioactive waste management is considered has evolved over time. The early period where radioactive waste was a non-issue was succeeded by a period of intense conflict over solutions. The contemporary context is more consensual, in which solutions are sought that are both technically sound and socially acceptable. Among the major issues is that of inter-generational equity embraced in the question: how long can or should our responsibility to the future extend? He pointed out the differences in timescales. On the one hand, geo-scientific timescales are very long term, emphasizing the issue of how far into the future it is possible to make predictions about repository safety. By contrast, socio cultural timescales are much shorter, focusing on the foreseeable future of one or two generations and raising the issue of how far into the future we should be concerned. He listed. the primary expectations from society which are: safety and security to alleviate undue burdens to future generations and flexibility in order to enable the future generations to have a stake in decision making. The need to reconcile the two had led to a contemporary emphasis on phased geological disposal incorporating retrievability. However, the long timescales for implementation of disposal provided for sufficient flexibility without the need for retrievability. Future generations would inevitably have sold stake in decision making. Prof. A.. Blowers pointed out that society is also concerned with participation in decision making for implementation. The key elements for success are: openness and transparency, staged process, participation, partnership, benefits to enhance the well being of communities and a democratic framework for decision making, including the ratification of key decisions and the right for communities to withdraw from the process up to a predetermined point. This approach for decision making may also have

  7. The Chinese nuclear program

    International Nuclear Information System (INIS)

    Prenez, J.C.; Bettoun, G.

    2009-01-01

    This series of slides presents the organization of the Chinese nuclear industry and its perspectives for the 2 next decades. The presentation is divided into 5 parts. Part one: the energy sector in China. Due to the economic development of the country this sector is flourishing and reaches an average growth rate of 9% per year. More than fifty per cent of the power plants being built in the world, are located in China. The electricity production stems by far from fossil energies (>80%) but this part is expected to decrease to reach 70% in 2020. Part 2: the Chinese nuclear program. This program is dual: the massive deployment of chinese improved reactors of second generation (the construction of 6 CPR1000 reactors will be launched each year) and the import and assimilation of reactors of the third generation: 4 AP1000 and 2 EPR are being built. Part 3: the organization of the Chinese nuclear sector. The main actors are CNNC (China National Nuclear Corporation), CGNPC (China Guangdong Nuclear Power Corporation), CPI (China Power Investment Corporation), SNPTC (State Nuclear Power Technology Corporation). The main 5 Chinese suppliers are also presented. Part 4: The role of EDF. Today's EDF role is multiple: to be active in the Chinese nuclear program, to go beyond technical assistance to reach partnership, to invest in Chinese power plants, to promote cooperation between French and Chinese actors of the nuclear industry. A lot of joint ventures have been created. Part 5: the Taishan project. Taishan is a coastal site near Macao in the Guangdong province in which 2 EPR are being built, the first concrete was cast in october 2009, 52 months of construction are scheduled and the first unit will be commissioned in end 2013 while the second commissioning is planned for end 2014. (A.C.)

  8. Chinese Entrepreneurs Go Global

    OpenAIRE

    Daniel Zhou

    2012-01-01

    China may be on the tipping point of explosive global growth. In response to changes in the global economy and an economic slowdown domestically, hundreds of thousands of Chinese SMEs are being encouraged to “go global” by their central and local governments. To a Chinese company, going global requires the expansion of its existing business in other countries or the development of new ventures with partners operating in other countries. Explosive growth in China may be possible, but it will d...

  9. Chinese Tourists in Denmark

    OpenAIRE

    Ooi, Can-Seng

    2007-01-01

    Tourism is entwined in economics, politics, culture, and social life. Despite Denmark’s attempt to re-brand itself as a modern, trendy and vibrant destination, the Danish tourism authorities is still selling the country’s historical sights and Hans Christian Andersen fairy tales to attract a growing number of Chinese tourists. While tourism authorities want to please the Chinese, other Danish authorities are concerned with overstaying tourists who may end up as illegal immigrants. On the Chin...

  10. LyC, Ly-alpha, and Low Ions in Green Peas: Diagnostics of Optical Depth, Geometry, and Outflows

    Science.gov (United States)

    Jaskot, Anne

    2015-10-01

    The Green Peas are extreme, low-redshift starbursts that are under intense scrutiny as a possible class of Lyman continuum (LyC) emitting galaxies. Their extreme [O III]/[O II] ratios resemble those of z>2 Ly-alpha emitters (LAEs) and suggest conditions conducive to high LyC escape fractions. Our initial COS study of four extreme GPs demonstrated the diagnostic power of Ly-alpha emission plus low-ionization absorption and emission lines to simultaneously relate optical depth, neutral gas geometry, and Ly-alpha radiative transfer. We now propose to test this understanding by confirming these relationships and trends: we will combine these data with new COS spectra of 13 of the most extreme GPs, extending our analysis to a statistically significant sample. One of the targets has the highest [O III]/[O II] ratio in the entire SDSS survey. The combined 17 total spectra of these rare, highly ionized starbursts will provide the first statistics on optical depth and Ly-alpha emission within this key, extraordinary galaxy population. The proposed COS observations will confirm whether galaxies with extreme [O III]/[O II] are indeed often optically thin and will likely lead to revealing the Ly-alpha profiles characteristic of LyC-emitting galaxies. By linking optical depth, outflow geometry, and Ly-alpha profiles, these observations will provide a vital basis for interpreting high-redshift LAE spectra.

  11. Optical computing: introduction by the feature editors.

    Science.gov (United States)

    Li, Y; Tanida, J; Tooley, F; Wagner, K

    1996-03-10

    This feature issue of Applied Optics: Information Processing contains 19 papers on Optical Computing. Many of these papers are expanded versions of presentations given at the Optical Society of America's Sixth Topical Meeting on Optical Computing held in Salt Lake City, Utah, in March 1995. This introduction provides a brief historical account of the series of optical computing meetings and a brief review of the papers contained in this special issue.

  12. Quench Protection Study of the Eurocircol 16 T cosθ Dipole for the Future Circular Collider (FCC)

    CERN Document Server

    AUTHOR|(CDS)2151660; Caiffi, Barbara; Fabbricatore, Pasquale; Farinon, Stefania; Salmi, Tiina-Mari; Sorbi, Massimo Leone; Stenvall, Antti; Volpini, Giovanni

    2016-01-01

    After LHC will be turned off, a new, more energetic machine will be needed in order to explore unknown regions of the high-energy physics. For this reason, the project Future Circular Collider (FCC) has started, with the goal of developing a 100 km circumference collider of 50 TeV proton beams. The Eurocircol collaboration is part of the FCC study under the European Community leadership, and it aims to develop a conceptual design of FCC within 2019. One of the main targets is to design a bending dipole able to reach 16 T operation magnetic field, in order to accomplish the size and energy constraints. Such a magnetic field can be reached using Nb3Sn conductors at their highest performance. One option under exploration is the Cosθ dipole, by INFN of Milano and Genova. One of the aspects to be taken into consideration is the amount of conductor needed, because of the relatively high cost of superconducting cables involving Nb3Sn. The amount of superconductor in the cross-section conductor area is a discriminan...

  13. Introduction to Optics

    CERN Document Server

    Chartier, Germain

    2005-01-01

    Since the discovery of the laser in 1960 and optical fibers in 1970, optics has undergone dramatic changes that accentuate its multi-disciplinary character. This text covers essential concepts and reports the key developments and progress in current knowledge in the field. Inspired by the style of Richard Feynman, the method of presentation emphasizes "telling" optics, rather than deducing it from fundamental laws, as well as tactfully using mathematical tools so as not to obscure the physical phenomena of interest. For its excellent teaching approach, the book received the Arnulf-Francon Award of the French Optical Society. The concepts are formulated in a way such that the necessary mathematical tools do not hinder comprehension of the phenomena. Global in vision, the book can also be used as a reference. In addition to the traditional aspects of optics, it includes the tools and methods currently used by researchers and engineers, as well as explanation and implications of the most recent developments.

  14. The Unified Phonetic Transcription for Teaching and Learning Chinese Languages

    Science.gov (United States)

    Shieh, Jiann-Cherng

    2011-01-01

    In order to preserve distinctive cultures, people anxiously figure out writing systems of their languages as recording tools. Mandarin, Taiwanese and Hakka languages are three major and the most popular dialects of Han languages spoken in Chinese society. Their writing systems are all in Han characters. Various and independent phonetic…

  15. Samuel Dyer and His Contributions to Chinese Typography.

    Science.gov (United States)

    Ismail, Ibrahim bin

    1984-01-01

    This history of a London Missionary Society member's contributions to typography development in China highlights selection of 3,000 Chinese characters needed for purpose of printing Christian books, production of temporary font from wooden blocks, and use of European methods of punches and matrices to produce permanent metal font. (Twenty-seven…

  16. A Study of the Chinese Shipyard Management Control System.

    Science.gov (United States)

    1987-09-01

    and the Cultural Revolution. During these periods different segments of Chinese society were subject to intense verbal and at times physical attack...Accoungnfrato SysteMk Unversy of Califonia, LoI ngl Feld, Robert M. "The Pfornunc of Induy During, the Cultura Revobstionc Second Thoughs, Thje Ch~m Qmwer

  17. Collectivistic Conflict of Chinese in Counseling: Conceptualization and Therapeutic Directions

    Science.gov (United States)

    Kwan, Kwong-Liem Karl

    2009-01-01

    Rapid Westernization and modernization in most Chinese societies has triggered a process of acculturation to Western value orientations, which induced conflicts between Confucian-based collectivism and Western individualism at both the societal and individual levels. A review of research instruments indicated that a cultural conflict approach is…

  18. Anorexia Nervosa in Chinese Adolescents: Does Culture Make a Difference?

    Science.gov (United States)

    Lai, Kelly Y. C.

    2000-01-01

    Reports on clinical and psychosocial characteristics of 16 Chinese adolescents from Hong Kong with anorexia nervosa. Over 80% of these patients expressed a fear of fatness. Against the background of increasing Westernization of Hong Kong society, anorexia is taking on a Western pattern, in congruence with the notion that anorexia nervosa is a…

  19. On the national characteristics of Chinese ancient architecture

    Science.gov (United States)

    Yan, Jun; Shan, Xiaoxian

    2018-03-01

    architecture is a complex composed of technology and art. It is a concrete reflection of everything in the local society at that time. The architecture is basically consistent with the social content and historical development. This paper analyzes the formation, characteristics and style of ancient Chinese architecture and expounds its national spirit and characteristics.

  20. Two-dimensional correlation spectroscopy (2D-COS) variable selection for near-infrared microscopy discrimination of meat and bone meal in compound feed.

    Science.gov (United States)

    Lü, Chengxu; Chen, Longjian; Yang, Zengling; Liu, Xian; Han, Lujia

    2014-01-01

    This article presents a novel method for combining auto-peak and cross-peak information for sensitive variable selection in synchronous two-dimensional correlation spectroscopy (2D-COS). This variable selection method is then applied to the case of near-infrared (NIR) microscopy discrimination of meat and bone meal (MBM). This is of important practical value because MBM is currently banned in ruminate animal compound feed. For the 2D-COS analysis, a set of NIR spectroscopy data of compound feed samples (adulterated with varying concentrations of MBM) was pretreated using standard normal variate and detrending (SNVD) and then mapped to the 2D-COS synchronous matrix. For the auto-peak analysis, 12 main sensitive variables were identified at 6852, 6388, 6320, 5788, 5600, 5244, 4900, 4768, 4572, 4336, 4256, and 4192 cm(-1). All these variables were assigned their specific spectral structure and chemical component. For the cross-peak analysis, these variables were divided into two groups, each group containing the six sensitive variables. This grouping resulted in a correlation between the spectral variables that was in accordance with the chemical-component content of the MBM and compound feed. These sensitive variables were then used to build a NIR microscopy discrimination model, which yielded a 97% correct classification. Moreover, this method detected the presence of MBM when its concentration was less than 1% in an adulterated compound feed sample. The concentration-dependent 2D-COS-based variable selection method developed in this study has the unique advantages of (1) introducing an interpretive aspect into variable selection, (2) substantially reducing the complexity of the computations, (3) enabling the transferability of the results to discriminant analysis, and (4) enabling the efficient compression of spectral data.

  1. In situ synthesis of 3D CoS nanoflake/Ni(OH)₂ nanosheet nanocomposite structure as a candidate supercapacitor electrode.

    Science.gov (United States)

    Li, Songzhan; Wen, Jian; Chen, Tian; Xiong, Liangbin; Wang, Jianbo; Fang, Guojia

    2016-04-08

    A three-dimensional (3D) CoS/Ni(OH)2 nanocomposite structure based on CoS nanoflakes and two-dimensional (2D) Ni(OH)2 nanosheets were in situ synthesized on Ni foam by a whole hydrothermal reaction and electrodeposition process. The 3D CoS/Ni(OH)2 nanocomposite structures demonstrate the combined advantages of a sustained cycle stability of CoS and high specific capacitance from Ni(OH)2. The obtained CoS/Ni(OH)2 nanocomposite structures on Ni foam can directly serve as a binder-free electrode for a supercapacitor. For the 3D CoS/Ni(OH)2 nanocomposite electrode, the high specific capacitance is 1837 F g(-1) at a scan rate of 1 mV s(-1), which is obviously higher than both the bare CoS electrode and Ni(OH)2 electrode. The galvanostatic charge and discharge measurements illustrate that the 3D CoS/Ni(OH)2 nanocomposite electrode possesses excellent cycle stability, and it keeps a 95.8% retention of the initial capacity after 5000 cycles. Electrochemical impedance spectroscopy measurements also confirm that the 3D CoS/Ni(OH)2 nanocomposite electrode has better electrochemical characteristics. These remarkable performances can be attributed to the unique 3D nanoporous structure of CoS/Ni(OH)2 which leads to a large accessible surface area and a high stability during long-term operation. In addition, 2D Ni(OH)2 nanosheets in 3D nanocomposite structures can afford rapid mass transport and a strong synergistic effect of CoS and Ni(OH)2 as individual compositions contribute to the high performance of the nanocomposite structure electrode. These results may promote the design and implementation of nanocomposite structures in advanced supercapacitors.

  2. The Secret Lives of Cepheids: Completing the Picture with HST-COS Observations of the Nearest Classical Cepheids, Polaris and delta Cephei

    Science.gov (United States)

    Engle, Scott

    2017-08-01

    Classical Cepheids, although well studied in terms of their cosmologically important Period-Luminosity Law, are proving to be increasingly complex and astrophysically intriguing in terms of atmospheric energetics. This proposal expands on data collected by us in previous cycles to probe Cepheid atmospheres, understand their heating mechanisms and answer important questions. Our previous COS FUV spectra revealed a wealth of 10,000-300,000K plasma emission lines, phase-locked with each Cepheid's pulsation periods, showing that a pulsation-driven heating mechanism is at work. To significantly expand the parameter space of the Cepheid sample, we propose four visits to the nearest and brightest Cepheid, Polaris. Only two COS spectra of Polaris were acquired previously. But we have now seen that Cepheids undergo fairly large FUV emission line variations (flux level differences of 20x and more). Observations of the ultra-low amplitude Polaris will offer remarkable insights into the effects that even minimal pulsations have on a cool supergiant atmosphere, especially when compared to full amplitude Cepheids and also non-pulsating supergiants in the instability strip. We have also recently proven that delta Cep is an X-ray variable, with a tight pulsation phase-range where the star's X-ray activity increases by over 4x. However, no COS spectra exist at this phase, which will be necessary to determine atmospheric densities and dynamics during the X-ray enhancement. When combined with our existing X-ray and FUV data set, the proposed COS data will advance a much deeper understanding of Cepheids and their atmospheric plasmas.

  3. Microclones derived from the mouse chromosome 7 D-E bands map within the proximal region of the c14CoS deletion in albino mutant mice

    International Nuclear Information System (INIS)

    Toenjes, R.R.W.; Weith, A.; Rinchik, E.M.; Winking, H.; Carnwath, J.W.; Kaliner, B.; Paul, D.

    1991-01-01

    A group of radiation-induced perinatal-lethal deletions that include the albino (c) locus on mouse chromosome 7 causes failure of expression of various hepatocyte-specific genes when homozygous. The transcription of such genes could be controlled in trans by a regulatory gene(s) located within the proximal region of the C14CoS deletion. To identify this potential regulatory gene, a microclone library was established from microdissected D and E bands of chromosome 7. Three nonoverlapping microclones (E305, E336B, and E453B) hybridizing with wildtype but not with C14CoS/C14CoS DNA were isolated. E336B represents a single-copy DNA fragment, whereas E305 and E453B hybridized with 3 and 10 EcoRI DNA restriction fragments, respectively. All fragments map exclusively within the deletion. The microclones hybridized to DNA of viable C6H/C14CoS deletion heterozygotes but not to DNA of homozygotes for the lethal mutation c10R75M, which belongs to the same complementation group as c14CoS. DNA of viable homozygous mutant C62DSD, which carries a deletion breakpoint proximal to that of c6H, hybridized only with E453B. This microclone identified 6 EcoRI restriction fragments in C62DSD/C62DSD DNA. The results demonstrate that of the isolated microclones, E453B identifies a locus (D7RT453B) that maps closest to the hsdr-1 (hepatocyte-specific developmental regulation) locus, which maps between the proximal breakpoints of deletions c10R75M and c62DSD

  4. Western medicine in a Chinese cultural setting.

    Science.gov (United States)

    Ho, Faith Chi Suk

    2009-01-01

    Hong Kong's unique medical heritage stems from its development as a city with a predominantly Chinese population and a long history of exposure to the influence of Western cultural and scientific ideas and practices. This heritage is preserved and displayed in the Hong Kong Museum of Medical Sciences, where exhibits of both Traditional Chinese Medicine and Western medicine, particularly those aspects with special relevance to Hong Kong, are featured. This paper also describes the significance of the plague outbreak of 1894 in shaping Hong Kong's medical history, and in bringing about the existence of the building which houses the museum, a 100 year-old protected monument originally named the Bacteriological Institute. The museum's role in society, by providing programmes on health and heritage for the public's education and enjoyment, and the need to preserve and identify both tangible and intangible aspects of our cultural heritage is also briefly explored.

  5. Shining Future of Biomedical Optics

    Science.gov (United States)

    Wang, Lihong

    2017-10-04

    Lihong V. Wang summarizes his tenure as Editor-in-Chief of the Journal of Biomedical Optics and introduces his successor, Brian Pogue, who will assume the role in January 2018. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  6. THE EVALUATION OF PEPTIDE/HISTIDINE TRANSPORTER 1 (PHT1) FUNCTION: UPTAKE KINETICS UTILIZING A COS-7 STABLY TRANSFECTED CELL LINE.

    Science.gov (United States)

    Lindley, David J; Carl, Stephen M; Mowery, Stephanie A; Knipp, Gregory T

    2011-10-01

    There have been relatively few studies focused on the proton-dependent oligopeptide transporter (POT) superfamily member, Peptide/Histidine Transporter 1 (PHT1), with respect to its contribution to the ADME of peptides and peptide-based drugs. These studies were conducted to determine hPHT1-mediated, H + -dependent uptake kinetics of histidine, carnosine, Gly-Sar and valacyclovir in stably transfected hPHT1-COS-7 cells comparative to kinetics determined in an empty vector (Mock) stably transfected cell line. The results suggest that Gly-Sar appears to be a substrate for PHT1 based on efflux from the stably transfected hPHT1 COS-7 cells. Histidine and Gly-Sar concentration- and time-dependent studies suggest mixed-uptake kinetics. These studies suggest that stably transfected hPHT1-COS-7 cells exhibit different uptake kinetics than those observed in our previous studies and illustrate the requirement for experiments to delineate the physiological role of hPHT1.

  7. Rapid authentication of different ages of tissue-cultured and wild Dendrobium huoshanense as well as wild Dendrobium henanense using FTIR and 2D-COS IR

    Science.gov (United States)

    Chen, Nai-Dong; Chen, Nai-Fu; Li, Jun; Cao, Cai-Yun; Wang, Jin-Mei

    2015-12-01

    The accumulating of pharmaceutical chemicals in medicinal plants would greatly be affected by their ages and establishing a fast quality-identification method to evaluate the similarity of medicinal herbs at different cultivated ages is a critical step for assurance of quality and safety in the TCM industry. In this work, tri-step IR macro-fingerprinting and 2D-COS IR spectrum techniques combined with statistical pattern recognition were applied for discrimination and similarity evaluation of different ages of tissue-cultured and wild Dendrobium huoshanense C. Z. Tang et S. J. Cheng as well as Dendrobium henanense J.L.Lu et L.X Gao. Both tissue-cultured and wild D. huoshanense were easily differentiated from D. henanense by FTIR and SD-IR spectra, while it's quite difficult to discriminate different cultivated years of the three investigated Dendrobiums. In 2D-COS IR spectra, 1-5 auto-peaks with different indensity and positions were located in the region 1160-1030 cm-1 of the twelve Dendrobium samples and thus could be used to identify Dendrobium samples at different ages. Principle component analysis (PCA) of synchronous 2D-COS data showed that the twelve samples were effectively identified and evaluated. The results indicated that the tri-step infrared macro-fingerprinting combined with PCA method was suitable to differentiate the cultivated ages of Dendrobiums with species and orgins rapidly and nondestructively.

  8. Resources available in society

    International Nuclear Information System (INIS)

    Berg, S.E.

    1997-01-01

    A decontamination operation will only be successful if cost-efficient methods are used. The cost-effectiveness depends, among many other factors, including the qualifications and training of the personnel and the capability of the equipment. The personnel must be able to handle the equipment in a professional way and should also know how to protect themselves. To fulfil these requirements they need courses in radiation protection. The equipment must be suitable for the selected countermeasure. Societies planning and preparedness for reclamation should meet realistic demands for early actions and outline a cost-effective strategy that implies reasonable use of personnel and equipment resources. Planning for early cleanup actions is different from that of long term planning with respect to the available time and quantity and quality of available information on which to base decisions. Available resources vary, of course, between the Nordic countries, but in all countries there are organisations with both knowledgeable staff and suitable equipment accessible for decontamination operations. (EG)

  9. Ethic, society and environment

    International Nuclear Information System (INIS)

    Angel Maya, Augusto

    2000-01-01

    This article is a reproduction of parts the fourth chapter of the book the return of Icaro, Death and life of the philosophy; the Universidad Autonoma de Occidente will publish that. The book intends to debate the crossroad in which any environmental interpretation is finned: penned between the reductionism of natural sciences and the philosophical sobrenaturalism of the social science. Between some natural sciences that don't understand the man and some social sciences that don't recognize the bonds with the nature if this approach is applied to the study of society or of culture, it would be necessary to understand it as the result of a evolutionary process, but also at the same time as a rupture with the previous evolutionary forms. The culture is not in the genes, but it has relationships with nature, the social sciences have not wanted to accept this fact. It has ethical and political consequences. As well as there is no ecosystem ethics, all human ethics should be aware of its relationships with the environment. Maybe this proposal will bring a new vision of what is freedom

  10. American Head and Neck Society

    Science.gov (United States)

    American Head & Neck Society Mission Statement: Advance Education, Research, and Quality of Care for the head and neck oncology patient. American Head & Neck Society | AHNS The mission of the AHNS is to ...

  11. Indicators of Information Society Measurement :

    Directory of Open Access Journals (Sweden)

    Hind Elwy

    2006-09-01

    Full Text Available The indicator of information society describe the infrastructure of information and communication technology ; as well as it’s use and it’s production in different estate of society. The importance economic and social of tic is crescent in modern society. and the presentation of tendency inform above the situation of information society . in this article we want to describe the indicator of tic in Algeria according to librarian’s vision in Mentouri university

  12. In situ preparation of NiS2/CoS2 composite electrocatalytic materials on conductive glass substrates with electronic modulation for high-performance counter electrodes of dye-sensitized solar cells

    Science.gov (United States)

    Li, Faxin; Wang, Jiali; Zheng, Li; Zhao, Yaqiang; Huang, Niu; Sun, Panpan; Fang, Liang; Wang, Lei; Sun, Xiaohua

    2018-04-01

    The electrocatalytic composite materials of honeycomb structure NiS2 nanosheets loaded with metallic CoS2 nanoparticles are in situ prepared on F doped SnO2 conductive glass (FTO) substrates used as counter electrodes of DSSCs through chemical bath deposition (CBD) and sulfidizing process. Single crystalline NiS2 honeycomb structure array lay a foundation for the large surface area of NiS2/CoS2 composite CEs. The formed NiS2/CoS2 nanointerface modulates electronic structure of composite CEs from the synergetic interactions between CoS2 nanoparticles and NiS2 nanosheets, which dramatically improves the electrocatalytic activity of NiS2/CoS2 composite CEs; Metallic CoS2 nanoparticles covering NiS2 nanosheets electrodes adjusts the electrodes' structure and then reduces the series resistance (Rs) and the Nernst diffusion resistance (Zw) of counter electrodes. The improvement of these areas greatly enhances the electrocatalytic performance of CEs and the short circuit current density (Jsc) and Fill factor (FF) of DSSCs. Impressively, the DSSC based on NiS2/CoS2-0.1 CE shows the best photovoltaic performance with photovoltaic conversion efficiency of 8.22%, which is 24.36% higher than that (6.61%) of the DSSC with Pt CE. And the NiS2/CoS2-0.1 CE also displays a good stability in the iodine based electrolyte. This work indicates that rational construction of composite electrocatalytic materials paves an avenue for high-performance counter electrodes of DSSCs.

  13. Creative Drama and Agricultural Societies.

    Science.gov (United States)

    Courtney, Richard

    1989-01-01

    Discusses the interaction of culture and creative drama. Examines agricultural societies under three conditions: historically, from neolithic times; contemporary American Southwest Indian and Polynesian; and modern farming subcultures of European industrial societies. Asks how far agricultural life influences creative drama in agrarian societies.…

  14. Knowledge society training system

    International Nuclear Information System (INIS)

    Ceclan, Mihail; Ionescu, Tudor Basarab; Ceclan, Rodica Elena; Tatar, Florin; Tiron, Cristian; Georgescu, Luisa Maria

    2005-01-01

    The paper aims to present the results of the Cernavoda NPP Training Department modernization project. In order to achieve a knowledge society training system, in the first stage of the project a Computer Based Training (CBT) or E-Learning software platform and several CBT objects/courses have been implemented. The conceived solution is called CBTCenter which is a complete E-Learning and CBT system, offering a variety of teaching and learning tools and services to its users. CBT and/or E-Learning always mean two things: a software platform and content authoring. Ideally, a software platform should be able to import any type of flat documentation and integrate it into a structured database which keeps track of pedagogically meaningful information like the student's progress in studying materials, tests and quizzes, grades, etc. At the same time, the materials, the study and the tests have to be organized around certain objectives which play the role of guidelines during the entire educational activity. An example of such a course which has been successfully integrated into CBTCenter is Labour safety - code name BB-001. The implementation of the CBT technology at NPP Cernavoda Training Department has brought several advantages: the technology improves overall communication between all individuals which take part in the educational process; the classroom space problem has been considerably reduced; students can access training materials from their own desk using the NPP intranet; the logistics problems will decrease with the conversion of more and more conventional courses and materials into CBT objects/courses. (authors)

  15. Symptom distress and its association with traditional Chinese medicine use in Chinese American women with cancer.

    Science.gov (United States)

    Liu, Shan; Sun, Yiyuan; Louie, Wendy

    2015-01-01

    To identify symptom distress related to cancer for a group of Chinese American women in treatment, and to examine their use of various forms of traditional Chinese medicine (TCM) and their relationships to specific symptoms they identified. Cross-sectional, correlational. American Cancer Society Asian Initiatives support groups in the state of New York. 97 Chinese American women residing in New York with a mean age of 57 years; the time since diagnosis of cancer ranged from two months to 24 years. The type of diagnosis for the majority of women was breast cancer. A self-reported questionnaire including a demographic data form, a researcher-developed checklist for types of TCM, and the Memorial Symptom Assessment Scale Short Form (MSAS-SF) were administered. The MSAS-SF has three subscales: global distress index, psychological symptom distress scale, and physical symptom distress scale. Symptoms, symptom distress, and types of TCM. The descriptive statistics and Mann-Whitney U tests were applied for data analysis. Chinese American women with cancer in treatment reported multiple symptoms, and the three MSAS-SF distress subscale scores indicated moderate symptom distress. Symptoms were positively associated with the use of TCM. Chinese American women in treatment for cancer reported multiple symptoms and moderate symptom distress. Participants with specific symptoms tended to use specific forms of TCM. High prevalence of psychological symptoms for Chinese American women with cancer suggests that oncology nurses should work with mental health providers for symptom management of this population. Oncology nurses also need to stay informed of the growing body of evidence on the benefits of TCM for patients with cancer. Future studies should include an emphasis on the improvement in methodologic quality for studies that investigate using TCM in participants with cancer.

  16. HST-COS observations of AGNs. II. Extended survey of ultraviolet composite spectra from 159 active galactic nuclei

    International Nuclear Information System (INIS)

    Stevans, Matthew L.; Shull, J. Michael; Danforth, Charles W.; Tilton, Evan M.

    2014-01-01

    The ionizing fluxes from quasars and other active galactic nuclei (AGNs) are critical for interpreting their emission-line spectra and for photoionizing and heating the intergalactic medium. Using far-ultraviolet (FUV) spectra from the Cosmic Origins Spectrograph (COS) on the Hubble Space Telescope (HST), we directly measure the rest-frame ionizing continua and emission lines for 159 AGNs at redshifts 0.001 < z AGN < 1.476 and construct a composite spectrum from 475 to 1875 Å. We identify the underlying AGN continuum and strong extreme ultraviolet (EUV) emission lines from ions of oxygen, neon, and nitrogen after masking out absorption lines from the H I Lyα forest, 7 Lyman-limit systems (N H I ≥10 17.2 cm –2 ) and 214 partial Lyman-limit systems (14.5

  17. The COS-Halos survey: physical conditions and baryonic mass in the low-redshift circumgalactic medium

    Energy Technology Data Exchange (ETDEWEB)

    Werk, Jessica K.; Prochaska, J. Xavier; Tejos, Nicolas [UCO/Lick Observatory, University of California, Santa Cruz, CA (United States); Tumlinson, Jason; Peeples, Molly S.; Fox, Andrew J.; Thom, Christopher; Bordoloi, Rongmon [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD (United States); Tripp, Todd M.; Katz, Neal [Department of Astronomy, University of Massachusetts, Amherst, MA (United States); Lehner, Nicolas [Department of Physics and Astronomy, University of Notre Dame, South Bend, IN (United States); O' Meara, John M. [Department of Chemistry and Physics, Saint Michael' s College, Colchester, VT (United States); Ford, Amanda Brady [Astronomy Department, University of Arizona, Tucson, AZ 85721 (United States); Oppenheimer, Benjamin D. [Leiden Observatory, Leiden University, NL-2300 RA Leiden (Netherlands); Davé, Romeel [University of the Western Cape, Bellville, Cape Town 7535 (South Africa); Weinberg, David H., E-mail: jwerk@ucolick.org [Department of Astronomy, The Ohio State University, Columbus, OH (United States)

    2014-09-01

    We analyze the physical conditions of the cool, photoionized (T ∼10{sup 4} K) circumgalactic medium (CGM) using the COS-Halos suite of gas column density measurements for 44 gaseous halos within 160 kpc of L ∼ L* galaxies at z ∼ 0.2. These data are well described by simple photoionization models, with the gas highly ionized (n {sub H} {sub II}/n {sub H} ≳ 99%) by the extragalactic ultraviolet background. Scaling by estimates for the virial radius, R {sub vir}, we show that the ionization state (tracked by the dimensionless ionization parameter, U) increases with distance from the host galaxy. The ionization parameters imply a decreasing volume density profile n {sub H} = (10{sup –4.2±0.25})(R/R {sub vir}){sup –0.8±0.3}. Our derived gas volume densities are several orders of magnitude lower than predictions from standard two-phase models with a cool medium in pressure equilibrium with a hot, coronal medium expected in virialized halos at this mass scale. Applying the ionization corrections to the H I column densities, we estimate a lower limit to the cool gas mass M{sub CGM}{sup cool}>6.5×10{sup 10} M {sub ☉} for the volume within R < R {sub vir}. Allowing for an additional warm-hot, O VI-traced phase, the CGM accounts for at least half of the baryons purported to be missing from dark matter halos at the 10{sup 12} M {sub ☉} scale.

  18. Paperless or vanishing society

    Science.gov (United States)

    Turner Luke, Joy

    2002-06-01

    In the 1940s color photography became available and within a few years, extremely popular. As people switched from black and white photographs made with the old metallic silver process to the new color films, pictures taken to record their lives and families began a slow disappearing act. The various color processes, coupled with the substrates they were printed on, affected their longevity, but many color photographs taken from the late 1950s through the 1970s, and even into the 1980s, faded not only when exposed to the light, but also when stored in the dark. Henry Wilhelm's excellent book 'The Permanence and Care of Color Photographs' documents this history in detail. Today we are making another transition in the storage of pictures and information. There are questions about the longevity of different types of digital storage, and also of the images printed by various types of inkjet printers, or by laser printers using colored toners. Very expensive and very beautiful works of art produced on Iris printers are appearing in art exhibitions. Some of these are referred to as Giclee prints and are offered on excellent papers. Artists are told the prints will last a lifetime; and if by change they don't it is only necessary to make another print. Henry Wilhelm has begun to test and rate these images for lightfastness; however, his test method was developed for examining longevity in colored photographs. It is of interest to find out how these prints will hold up in the tests required for fine art materials. Thus far companies producing digital inks and printers have not invested the time and money necessary to develop an American Society for Testing and Materials (ASTM) standard method for evaluating the lightfastness of digital prints. However, it is possible to use ASTM D 5383, Standard Practice for Visual Determination of the Lightfastness of Art Materials by Art Technologists, to pinpoint colors that will fade in a short time, even though the test is not as

  19. CERN & Society launches donation portal

    CERN Multimedia

    Cian O'Luanaigh

    2014-01-01

    The CERN & Society programme brings together projects in the areas of education and outreach, innovation and knowledge exchange, and culture and arts, that spread the CERN spirit of scientific curiosity for the inspiration and benefit of society. Today, CERN & Society is launching its "giving" website – a portal to allow donors to contribute to various projects and forge new relationships with CERN.   "The CERN & Society initiative in its embryonic form began almost three years ago, with the feeling that the laboratory could play a bigger role for the benefit of society," says Matteo Castoldi, Head of the CERN Development Office, who, with his team, is seeking supporters and ambassadors for the CERN & Society initiative. "The concept is not completely new – in some sense it is embedded in CERN’s DNA, as the laboratory helps society by creating knowledge and new technologies – but we would like to d...

  20. Chinese students' great expectations

    DEFF Research Database (Denmark)

    Thøgersen, Stig

    2013-01-01

    The article focuses on Chinese students' hopes and expectations before leaving to study abroad. The national political environment for their decision to go abroad is shaped by an official narrative of China's transition to a more creative and innovative economy. Students draw on this narrative to...... system, they think of themselves as having a role in the transformation of Chinese attitudes to education and parent-child relations.......The article focuses on Chinese students' hopes and expectations before leaving to study abroad. The national political environment for their decision to go abroad is shaped by an official narrative of China's transition to a more creative and innovative economy. Students draw on this narrative...

  1. Optical conductivity of the triplet superconductor Sr2RuO4

    International Nuclear Information System (INIS)

    Virosztek, Attila; Dora, Balazs; Maki, Kazumi

    2003-10-01

    Now the spin triplet superconductivity in Sr 2 RuO 4 is well established. As to the nodal structures seen in high quality samples, there are two alternative models at present: a. 2D f-wave model with Δ(k) ∼ (k-circumflex x ± ik-circumflex y ) cos(ck z ) and b. the multigap model with Δ 1 (k) ∼ (k-circumflex x ± ik-circumflex y ) and Δ 2 (k) ∼ (k-circumflex x ± ik-circumflex y ) cos(ck z /2). In this paper we calculate the optical conductivity for T e in the 2D f-wave model and show that it differs significantly from those in the multigap model. (author)

  2. Re-Interpreting the "Chinese miracle"

    DEFF Research Database (Denmark)

    Feng, Xingyuan; Ljungwall, Christer; Guo, Sujian

    2011-01-01

    The rapid economic development and transformation of Chinese society over the past three decades has, by a large mass of analysts, been called a "Miracle." This paper not only addresses the shortcomings of existing interpretations but also develops a new multi-dimensional framework based on North......'s theory of institutional change and Hayek's theory of institutional evolution to explain China's miraculous growth. Our analysis shows that both Hayekian spontaneous order and Popper's "piecemeal social engineering" played a major role in attaining China's miraculous growth....

  3. Concepts of Chinese Folk Happiness

    Science.gov (United States)

    Ip, Po Keung

    2011-01-01

    Discourses on Chinese folk happiness are often based on anecdotal narratives or qualitative analysis. Two traditional concepts of happiness popular in Chinese culture are introduced. The paper constructs a concept of Chinese folk happiness on basis of the findings of a scientific survey on the Taiwanese people regarding their concepts of…

  4. CHINESE ENTREPRENEURIAL ACTIVITY IN PORTUGAL: TRADITIONAL ETHNIC STRATEGIES?

    Directory of Open Access Journals (Sweden)

    Catarina Reis Oliveira

    2010-12-01

    Full Text Available In Portugal in recent decades, just like in other welcoming countries, immigrants have reached levels of entrepreneurial activity that are higher than those of autochthonous citizens. However, a deeper analysis of the official data shows that not all immigrant groups have the same tendency to become entrepreneurs. In this respect, the Chinese stand out as being the group with the highest ratio of entrepreneurial activity in Portugal, despite the fact that their migration is a relatively recent phenomenon. What factors can explain the Chinese community’s disproportionate rate of entrepreneurial initiative? Do they possess any particular resources that make them more enterprising than the autochthonous population, or than other groups of immigrants? Does the context of Portugal hamper certain opportunities or in some way limit their economic integration into the job market? Do we find similar business strategies among other Chinese entrepreneurs residing in welcoming societies apart from that of Portugal? Why did Chinese business initiative grow at such an exceptional rate in Portugal in the late 1990s? By seeking answers to these questions, this article attempts to examine Chinese business strategies in Portugal, as well as their exceptional success rate in comparison with other entrepreneurial immigrants. To that end, the author has analysed the data gathered in a survey carried out on 309 Chinese entrepreneurs resident in Portugal (see Oliveira, 2005.

  5. Violence in society

    Directory of Open Access Journals (Sweden)

    António Pedro de Andrade Dores

    2014-07-01

    Full Text Available The recent interest in the sociology of violence has arisen at the same time that western societies are being urged to consider the profound social crisis provoked by global financial turmoil. Social changes demand the evo- lution of sociological practices. The analysis herein proposed, based on the studies of M. Wieviorka, La Violence (2005, and of R. Collins, Violence: A Micro-sociological Theory (2008, concludes that violence is subject to sociological treatments cen- tered on the aggressors, on the struggles for power and on male gender. There is a lack of connection between prac- tical proposals for violence prevention and the sociol- ogy of violence. It is accepted that violence as a subject of study has the potential, as well as the theoretical and social centrality, to promote the debate necessary to bring social theory up to date. This process is more likely to oc- cur in periods of social transformation, when sociology is open to considering subjects that are still taboo in its study of violence, such as the female gender and the state. The rise of the sociology of violence confronts us with a dilemma. We can either collaborate with the construc- tion of a sub discipline that reproduces the limitations and taboos of current social theory, or we can use the fact that violence has become a “hot topic” as an opportunity to open sociology to themes that are taboo in social the- ory (such as the vital and harmonious character of the biological aspects of social mechanisms or the normative aspects of social settings. ResumenEl interés reciente en la sociología de la violencia ha surgido al mismo tiempo que las sociedades occidenta- les están requiriendo considerar la profunda crisis social provocada por la agitación financiera global. Los cambios sociales demandan la evolución de las prácticas socioló- gicas. El análisis aquí expuesto, basado en los estudios de M. Wieviorka, La Violence (2005, and of R. Collins

  6. Danish-accented Chinese

    DEFF Research Database (Denmark)

    Wang, Lei; Sloos, Marjoleine 莱娜; Zhang, Chun

    the perception and production. We hypothesize that the phonological system and the variation in the pronunciation of in Danish is responsible for the production difficulty and will in a production and a perception experiment where lie the categorical boundaries of the students between tai and cai in a series...... of experiments. Further we will investigate the perception and production of tone among Danish students, as well as the tone perception of Chinese native speakers (with and without exposure to Danish) when they perceive Danish accented Chinese. Of special interest is the neutral tone: without particular...

  7. Perspectives on Family Health, Happiness and Harmony (3H) among Hong Kong Chinese People: A Qualitative Study

    Science.gov (United States)

    Lam, W. W. T.; Fielding, R.; McDowell, I.; Johnston, J.; Chan, Sophia; Leung, G. M.; Lam, T. H.

    2012-01-01

    Family harmony, an important Confucian ideal in Chinese society is believed to determine family happiness and therefore health, but is this accurate? This is a qualitative study of 41 Hong Kong Chinese family members. Individual recorded interviews were thematically analysed describing perceived interactions between harmony, happiness and health.…

  8. Predictors of Dating Violence among Chinese Adolescents: The Role of Gender-Role Beliefs and Justification of Violence

    Science.gov (United States)

    Shen, April Chiung-Tao; Chiu, Marcus Yu-Lung; Gao, Jianxiu

    2012-01-01

    In Chinese societies, violence among adolescent dating partners remains a largely ignored and invisible phenomenon. The goal of this study is to examine the relationships among gender-role beliefs, attitudes justifying dating violence, and the experiences of dating-violence perpetration and victimization among Chinese adolescents. This study has…

  9. Impulsivity as a Moderator and Mediator between Life Stress and Pathological Gambling among Chinese Treatment-Seeking Gamblers

    Science.gov (United States)

    Tang, Catherine So-kum; Wu, Anise M. S.

    2012-01-01

    This study examined the role of impulsivity and its interplay with gambling correlates in influencing the severity of pathological gambling in Chinese societies. It also investigated the extent to which impulsivity would moderate and/or mediate the relationship between life stress and pathological gambling in 94 Chinese treatment-seeking gamblers.…

  10. Quantum optics

    National Research Council Canada - National Science Library

    Agarwal, G. S

    2013-01-01

    .... Focusing on applications of quantum optics, the textbook covers recent developments such as engineering of quantum states, quantum optics on a chip, nano-mechanical mirrors, quantum entanglement...

  11. Being Chinese or Being Different: Chinese Undergraduates' Use of Discourses of Chineseness

    Science.gov (United States)

    Skyrme, Gillian

    2014-01-01

    Myths about "the Chinese learner" developed from an outsider perspective abound in the Western world. The focus of this article, however, is how discourses of Chineseness were used by the Chinese international students themselves who, as undergraduate students in a New Zealand university, were the subjects of my doctoral research. It…

  12. 48. annual symposium of the Austrian Physical Society

    International Nuclear Information System (INIS)

    Netzer, F.P.

    1998-01-01

    This volume contains short communications of lectures and posters of the 48 th Symposium of the Austrian Physical Society which had been held at the University of Graz (Austria) in 1998. The following topics are included: atomic physics, molecular physics, plasma physics, solid state physics, nuclear and particle physics, polymer physics, biophysics, environmental physics, quantum electronics and quantum optics. (Suda)

  13. 45. Annual Convention of the Austrian Physical Society

    International Nuclear Information System (INIS)

    1995-01-01

    This volume contains lectures of the 45 th symposium of the Austrian Physical Society which had been held in Leoben, Austria in 1995. The following topics are included: Atomic physics, molecular physics, plasma physics, solid state physics, nuclear and particle physics, biophysics, environmental physics, quantum electronics and quantum optics. (Suda)

  14. The Israel Physical Society 1997 Annual Meeting. Program and abstracts

    International Nuclear Information System (INIS)

    1997-01-01

    The book of program and abstracts of the 43rd meeting of the Israel physical society presents abstracts of presentations in various field of physics. Follow is the list of these fields. Astrophysics, condensed matter, laser and quantum optics, nuclear physics, particle and fields, physics in biology, physics in industry, plasma and space physics, statistical physics and nonlinear dynamics

  15. 50. Annual symposium of the Austrian Physical Society

    International Nuclear Information System (INIS)

    Lippitsch, M.E.

    2000-01-01

    The conference held from 25. - 29. 9. 2000 at the University of Graz was elaborated by the Austrian society of physics in the fields of solid state physics, polymers physics, quantum electronics, electrodynamics, optics, nuclear and particle physics, atomic, molecules and plasma physics, acoustics, physics - industry - energy and physics teaching. (botek)

  16. Israel Physical Society 44. annual meeting. Program and abstracts

    International Nuclear Information System (INIS)

    1998-01-01

    During the 1998 Annual Conference of the Israel Physical Society, various chapters were treated in parallel sessions: Physics teaching, Condensed matter, Lasers and Quantum Optics, Atomic and Nuclear physics, Particles and Fields, Statistical physics and nonlinear dynamics, Physics in industry, Plasma physics and computational physics

  17. 47. annual symposium of the Austrian Physical Society

    International Nuclear Information System (INIS)

    Kutschera, W.

    1997-01-01

    This volume contains lectures (short communications) of the 47. symposium of the Austrian Physical Society which had been held at the University of Vienna (Austria) in 1997. The following topics are included: atomic physics, molecular physics, plasma physics, solid state physics, nuclear and particle physics, biophysics, environmental physics, quantum electronics and quantum optics. (Suda)

  18. 49. annual symposium of the Austrian Physical Society

    International Nuclear Information System (INIS)

    Blatt, R.; Maerk, T.

    1999-01-01

    This volume contains short communications of lectures and poster sessions of the 49th symposium of the Austrian Physical Society which has been held at the University of Innsbruck (Austria) in 1999. The following topics are included: atomic physics, molecular physics, plasma physics, solid state physics, nuclear and particle physics, polymer physics, biophysics, environmental physics, quantum electronics and quantum optics. (Suda)

  19. Science communication at scientific societies.

    Science.gov (United States)

    Braha, Jeanne

    2017-10-01

    Scientific societies can play a key role in bridging the research and practice of scientists' engagement of public audiences. Societies are beginning to support translation of science communication research, connections between scientists and audiences, and the creation of opportunities for scientists to engage publics without extensive customization. This article suggests roles, strategies, and mechanisms for scientific societies to promote and enhance their member's engagement of public audiences. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Multivariable Chinese Remainder Theorem

    Indian Academy of Sciences (India)

    IAS Admin

    number as sought since N could be negative. However, we may add a suitable multiple of m1m2 to N ... Further, we note that negative numbers are dealt on an equal footing; the statement that x leaves a remainder .... classical Chinese remainder theorem can be thou- ght of as the special case when the matrix {aij} has only.

  1. SWOT ANALYSIS - CHINESE PETROLEUM

    Directory of Open Access Journals (Sweden)

    Chunlan Wang

    2014-01-01

    Full Text Available This article was written in early December 2013,combined with the historical development andthe latest data on the Chinese Petroleum carried SWOT- analysis. This paper discusses corporate resources, cost, management and external factorssuch as the political environment and the marketsupply and demand, conducted a comprehensiveand profound analysis.

  2. Milestone for Chinese physicists

    CERN Multimedia

    2003-01-01

    Chinese scientists have discovered a new particle predicted decades ago but never observed before. It could be what was once called the "multi-quark state," tiny elementary particles with a strong interaction or force that serves as the source of nuclear energy (1/2 page).

  3. Equilibria of Chinese Auctions

    DEFF Research Database (Denmark)

    Branzei, Simina; Forero, Clara; Larson, Kate

    are symmetric when both valuations and budgets are symmetric. We also study Chinese auctions with discrete budgets, for which we give both existence results and counterexamples. While the literature on rent-seeking contests traditionally focuses on continuous costly tickets, the discrete variant is very natural...

  4. Chinese Entrepreneurs Go Global

    Directory of Open Access Journals (Sweden)

    Daniel Zhou

    2012-02-01

    Full Text Available China may be on the tipping point of explosive global growth. In response to changes in the global economy and an economic slowdown domestically, hundreds of thousands of Chinese SMEs are being encouraged to “go global” by their central and local governments. To a Chinese company, going global requires the expansion of its existing business in other countries or the development of new ventures with partners operating in other countries. Explosive growth in China may be possible, but it will depend on an appropriate strategy for going global. For a country that has firmly established itself as an international manufacturing hub, going global requires a shift in its entrepreneurial capacity, which is the focus of this article. We first assess the current situation in China to understand its current entrepreneurial focus and capacity, as well as the impetus for change. Next, we contrast the Kirznerian and Schumpeterian views of entrepreneurship to illustrate that – to go global – Chinese entrepreneurs must shift from an emphasis on exploiting pricing inefficiencies (i.e., Kirznerian entrepreneurship to an emphasis on innovation (i.e., Schumpeterian entrepreneurship. Finally, we examine unique characteristics of the business environment and culture in China, which are likely to impact the ability of Chinese entrepreneurs to go global.

  5. Modelling Chinese Smart Grid

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    In this document, we consider a specific Chinese Smart Grid implementation and try to address the verification problem for certain quantitative properties including performance and battery consumption. We employ stochastic model checking approach and present our modelling and analysis study using...

  6. The Imperative in Chinese.

    Science.gov (United States)

    Hashimoto, Anne Yue

    A preliminary study of the syntactic characteristics of the imperative construction in modern Chinese is presented. The term "imperative" is used to refer to the type of syntactic construction which is marked by an implicit or explicit second person subject, and which expresses a direct command. Indirect or implied commands expressed by a…

  7. Digital Denmark: From Information Society to Network Society

    DEFF Research Database (Denmark)

    Henten, Anders; Falch, Morten

    2000-01-01

    The Danish Government recently issued a new policy report, Digital Denmark, on the "conversion to a network society", as a successor to its Information Society 2000 report (1994). This is part of a new round of information society policy vision statements that are, or will be forthcoming from...... national governments everywhere. Denmark provides an interesting case study because it ranks high in the benchmark indicators of information network society developments. This position has been obtained largely by public sector initiatives and without erosion of the highly reputed Scandinavian model...... for a welfare society. However, globalisation and the spreading use of new information and communication technologies and services challenge this position. This article examines Denmark's performance in implementing its IS 2000 plans, the background to the Digital Denmark report, and its implications...

  8. Traditional Chinese Medicine Use and Health in Community-Dwelling Chinese-American Older Adults in Chicago.

    Science.gov (United States)

    Dong, XinQi; Bergren, Stephanie M; Chang, E-Shien

    2015-12-01

    Chinese people have practiced traditional Chinese medicine (TCM) for thousands of years, but there is a paucity of research regarding TCM use in Chinese older adult immigrants in the United States. This study aims to provide an overall estimate of TCM use for Chinese older adults in the United States and to examine associations between sociodemographic characteristics, health measures, and TCM use. Data were collected through the Population Study of Chinese Elderly in Chicago, a community-based participant research study that surveyed 3,158 Chinese older adults aged 60 and older. TCM use was measured using an eight-item scale that examined eight kinds of TCM. Seventy-six percent of participants reported any use of TCM within the past year. After adjusting for potential confounding factors, health status was associated with greater use of acupuncture (odds ratio (OR) = 1.33, 95% confidence interval (CI) = 1.06-1.68) and massage therapy (OR = 1.53, 95% CI = 1.21-1.93), and quality of life was associated with less use of prescribed herbal products (OR 0.69, 95% CI = 0.55-0.87), tai chi (OR = 0.62, 95% CI = 0.50-0.78), and other traditional medicine (OR = 0.47, 95% CI = 0.40-0.56). These findings call for further investigation of TCM use by Chinese older adults, especially those with poor health and those with better quality of life. In the clinical setting, physicians should have awareness of TCM when treating Chinese older adults and look toward possible integration with Western medicine for more culturally appropriate, patient-centered care. © 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society.

  9. Optical Computing

    Indian Academy of Sciences (India)

    Optics has been used in computing for a number of years but the main emphasis has been and continues to be to link portions of computers, for communications, or more intrin- sically in devices that have some optical application or component (optical pattern recognition, etc). Optical digi- tal computers are still some years ...

  10. Translation and validation of the Chinese versions of the Suicidal Ideation Attributes Scale, Stigma of Suicide Scale, and Literacy of Suicide Scale.

    Science.gov (United States)

    Han, Jin; Batterham, Philip J; Calear, Alison L; Wu, Yang; Shou, Yiyun; van Spijker, Bregje A J

    2017-03-01

    This article reports the validation of the Chinese versions of the Suicidal Ideation Attributes Scale (SIDAS), the short form of Stigma of Suicide Scale (SOSS), and the short form of Literacy of Suicide Scale (LOSS) among 57 Chinese and English bilinguals and 224 Chinese university students. All the translated scales showed high correlations with the original versions. The translated SIDAS and refined SOSS demonstrated robust factor structures, good internal consistency, and convergent validity. Chinese students with self-reported depression symptoms tended to have higher glorification of suicide and lower suicide literacy. These brief scales fill an important gap in evaluating suicide outcomes in Chinese-speaking societies.

  11. Education in the Information Society

    Directory of Open Access Journals (Sweden)

    Octavia-Luciana Porumbeanu

    2007-01-01

    Full Text Available This article approaches the fundamental role which education has in the information society. The continuous evolution of information and communication technologies requires that all citizens have the necessary skills have to use these technologies and to access information for efficient individual functioning in the information society. In this context, the information literacy programmes have a growing importance.

  12. YOUTH AND THE CHANGING SOCIETY.

    Science.gov (United States)

    MILLER, S.M.

    THE YOUNG JOB HOLDER WILL NEED TO CHANGE HIS SKILLS SEVERAL TIMES DURING HIS WORKING LIFE. HE HAS LITTLE TRAINING OR RESOURCES, AND SOCIETY HAS DONE LITTLE TO HELP. THE NUMBER OF UNEMPLOYED YOUTH IS GROWING. OUR SOCIETY IS BECOMING MORE AND MORE A PLACE WHERE ONE'S CREDENTIALS HELP HIM SUCCEED. A COLLEGE DIPLOMA IS BECOMING A PREREQUISITE TO…

  13. Public Libraries in postindustrial societies

    DEFF Research Database (Denmark)

    Elbeshausen, Hans

    2015-01-01

    The article’s focus is on how public libraries are affected by structural changes in the wake of the transition to the knowledge society. Their attempts to match the knowledge society are illustrated by processes of sensemaking and sensegiving made in public libraries in Canada, the UK and Denmark....

  14. Rapid characterization of disease-causing mutations in the low density lipoprotein receptor (LDL-R) gene by overexpression in COS cells

    DEFF Research Database (Denmark)

    Jensen, T G; Andresen, B S; Jensen, H K

    1996-01-01

    To characterize disease-causing mutations in the low density lipoprotein receptor (LDL-R) gene, COS cells are transfected with the mutant gene in an EBV-based expression vector and characterized by flow cytometry. Using antibodies against the LDL-receptor the amount of receptor protein on the cell...... surface is quantitated. The receptor activity is measured by incubating the cells with fluorescence labeled LDL (Dil-labelled LDL) at 37 degrees C and 4 degrees C. The transfected cells stained with anti-LDL-R antibodies can also be analysed by immunofluorescence microscopy allowing the study...

  15. KEYNOTE ADDRESS OF THE SEVENTH INTERNATIONAL CONFERENCE ON THE HEALTH OF CHINESE IN NORTH AMERICA: Health Status of Chinese Americans: Challenges and Opportunities.

    Science.gov (United States)

    Chen, Moon S.

    1995-01-01

    PURPOSE. This paper is based on the author's keynote address given at the Seventh International Conference on the Health Problems of Chinese in North America. METHODS. The author/speaker reviewed the literature related to Chinese American health problems within the context of the broader demographic and aggregated health data reported on Asian Americans and Pacific Islanders. FINDINGS. In addition to background demographic statistics provided on Chinese Americans, the author/speaker focused on two categories of diseases: (1) communicable diseases; and (2) chronic diseases because of the greater availability of data on these categories. Communicable diseases from which Chinese Americans appear to suffer disproportionally are tuberculosis and hepatitis B. Infection with the hepatitis B virus also makes Chinese Americans much more susceptible to chronic liver diseases including cancer. Chinese also suffer disproportionally more from nasopharyngeal cancer; because of higher than average adult male smoking rates, these men can be expected to suffer disproportionally from a future epidemic of lung cancer cases. Unhealthy acculturation patterns in food consumption point towards changing profiles of cardiovascular morbidity and mortality as well as higher rates of dietary related cancers. OBSERVATIONS. Rather than conclusions, observations of the current health status of Chinese Americans were offered. Four measures that organizations such as the Chinese medical societies and Chinese American health professionals can pursue to advance the health status of Chinese Americans, particularly in the area of heaslth policy, are: (1) voting; (2) collecting data on health status; (3) writing for professional journals; and (4) being active in policy development. KEY WORDS. Chinese Americans; health status; tuberculosis; hepatits B; cancer; diet; acculturation; smoking

  16. What is the Knowledge Society?

    Directory of Open Access Journals (Sweden)

    Marin Dinu

    2008-02-01

    Full Text Available This study sets out to establish conceptual delimitations, more concordant to the theoretical acquisitions with regard to the knowledge society. The author considers it opportune to situate in the center of the definition of the concept of knowledge society the problem of prevalence in the typology of resources. Thus, the knowledge society appears as a form of organization in which scientific knowledge predominates, be that informatics as well. The concordances of essence are discovered through the discerning of the functional relationship knowledge society – global society. In the spectrum of meanings specific to this highway of post-postmodernist configuration of the world, the priorities of the project of the second modernity – the paradigmatic matrix of globalization – are approached. In fact, the study argues in favor of refocusing globalization on the humane, on its distinctive values which substantiate and lend sense to the evolutions of the world. Postreferentiality is the rational expression of humanity coming back to itself.

  17. Nephrotoxicity and Chinese Herbal Medicine.

    Science.gov (United States)

    Yang, Bo; Xie, Yun; Guo, Maojuan; Rosner, Mitchell H; Yang, Hongtao; Ronco, Claudio

    2018-04-03

    Chinese herbal medicine has been practiced for the prevention, treatment, and cure of diseases for thousands of years. Herbal medicine involves the use of natural compounds, which have relatively complex active ingredients with varying degrees of side effects. Some of these herbal medicines are known to cause nephrotoxicity, which can be overlooked by physicians and patients due to the belief that herbal medications are innocuous. Some of the nephrotoxic components from herbs are aristolochic acids and other plant alkaloids. In addition, anthraquinones, flavonoids, and glycosides from herbs also are known to cause kidney toxicity. The kidney manifestations of nephrotoxicity associated with herbal medicine include acute kidney injury, CKD, nephrolithiasis, rhabdomyolysis, Fanconi syndrome, and urothelial carcinoma. Several factors contribute to the nephrotoxicity of herbal medicines, including the intrinsic toxicity of herbs, incorrect processing or storage, adulteration, contamination by heavy metals, incorrect dosing, and interactions between herbal medicines and medications. The exact incidence of kidney injury due to nephrotoxic herbal medicine is not known. However, clinicians should consider herbal medicine use in patients with unexplained AKI or progressive CKD. In addition, exposure to herbal medicine containing aristolochic acid may increase risk for future uroepithelial cancers, and patients require appropriate postexposure screening. Copyright © 2018 by the American Society of Nephrology.

  18. Introduction: Feature Issue on Optical Imaging and Spectroscopy

    OpenAIRE

    Hielscher, Andreas H.; Mycek, Mary-Ann; Perelman, Lev T.

    2010-01-01

    The editors introduce the Biomedical Optics Express feature issue, “Optical Imaging and Spectroscopy,” which was a technical area at the 2010 Optical Society of America (OSA), Biomedical Optics (BIOMED) Topical Meeting held on 11–14 April in Miami, Florida. The feature issue includes 23 contributions from conference attendees.

  19. Introduction: Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy

    OpenAIRE

    Li, Xingde; Beard, Paul C.; Georgakoudi, Irene

    2010-01-01

    The editors introduce the Biomedical Optics Express feature issue, “Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy,” which combines three technical areas from the 2010 Optical Society of America (OSA), Biomedical Optics (BIOMED) Topical Meeting held on 11–14 April in Miami, Florida, and includes contributions from conference attendees.

  20. Home language shift and its implications for Chinese language teaching in Singapore

    Directory of Open Access Journals (Sweden)

    Li Li

    2016-12-01

    Full Text Available In a bilingual society like Singapore, home language environment (HLE of Singaporean children is becoming increasingly concerned, especially for those who are yet to have formal education in schools. The reported rapid shift of family language has increased the tensions among families, schools and communities. This study examined some of the many facets of Singaporean Chinese preschoolers’ HLE, and further discussed how these facets are related to children’s Chinese language proficiency in oral and written forms. Three hundred and seventy-six Singaporean Chinese six-year olds completed Chinese oral and written language proficiency screening. Their parents completed a HLE survey. The findings revealed the possible trend of home language shift from Mandarin Chinese to English in the younger generation. Aside from home language use factors, the importance of other facets that form a rich language environment is also highlighted for children's language development.