WorldWideScience

Sample records for correlation method investigacao

  1. Investigation of hyperfine parameters of semiconductor oxides SnO{sub 2} and TiO{sub 2} pure and doped with 3d transition methods using spectroscopy of perturbed gamma-gamma angular correlation; Investigacao de parametros hiperfinos dos oxidos semicondutores SnO{sub 2} and TiO{sub 2} puros e dopados com metais de transicao 3d pela espectroscopia de correlacao angular gama-gama perturbada

    Energy Technology Data Exchange (ETDEWEB)

    Schell, Juliana

    2015-09-01

    This study aimed the use of nuclear technique Perturbed γ-γ Angular Correlation Spectroscopy (PAC) to measure the hyperfine interactions in thin films and powder samples of SnO{sub 2} and TiO{sub 2} pure and doped with transition metals to obtain a systematic investigation of defects and magnetism from an atomic point of view with the main motivation the application in spintronics. The work also focused on the preparation and characterization of samples by conventional techniques such as X-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy and magnetization measurements. Pure samples of the films were measured by the systematic variation of thermal treatment and applied magnetic field. These measurements were performed in HISKP at the University of Bonn (Rheinische Friedrich-Wilhelms-Universität Bonn) using {sup 111}In({sup 111}Cd) or {sup 181}Hf ({sup 181}Ta); at IPEN, in turn, these measurements were performed after the diffusion of the same probe nuclei. Another part of PAC measurements were carried out using {sup 111}mCd({sup 111}Cd) and {sup 117}Cd ({sup 117}In) in Isotope Mass Separator On-Line (ISOLDE) at Centre Européen Recherche Nucléaire (CERN). The measurements were performed from 8 K to 1173 K. After comparing results from macroscopic techniques with those from PAC, it was concluded that there is a correlation between the defects, magnetism and the mobility of charge carriers in semiconductors studied here. A step forward in the search for semiconductors, whose magnetic ordering allows its use in electronics based on spin. Some results have been published, including results obtained at the University of Bonn for the sandwich doctorate period [1-7]. (author)

  2. Investigation of hyperfine interactions in pure silicon and NTD silicon by means of perturbed angular {gamma}-{gamma} correlation spectroscopy; Investigacao de interacoes hiperfinas em silicio puro e silicio NTD pela tecnica de correlacao angular {gamma}-{gamma} perturbada

    Energy Technology Data Exchange (ETDEWEB)

    Cordeiro, Moacir Ribeiro

    2007-07-01

    III the present work, a microscopic investigation of hyperfine interactions in single crystal silicon samples was carried out by means of Perturbed Angular {gamma} -{gamma} correlation technique (PAC), which is based in hyperfine interactions. In order to achieve these measurements, it was used {sup 111} In {yields} {sup 111}Cd radioactive probe nuclei, which decay through the well known {gamma} cascade 171-245 keV with an intermediate level of 245 keV ( I 5{sup +}/2, Q = 0.83b, T{sub 1/2} = 84.5 ns). The samples were prepared using different probe nuclei insertion methods, making possible to increase our understanding on the impact generated by each of these techniques in PAC measurements. Ion implantation, diffusion and evaporation were carefully investigated giving emphasis on its characteristics and particularities. Then, it was made a study about the concentration of intrinsic defects as function of severe annealing processes. Finally, a comparative analysis was made for all these probe nuclei insertion methods. This work also accomplished PAC measurements in single crystal silicon doped with phosphorus by means of Neutron Transmutation Doping (NTD) method, carried out in a research nuclear reactor. The extremely high doping uniformity allied to the nonexistence of previous measurements in these materials emphasize the importance of the results obtained. These results are then compared with literature results for samples doped by conventional methods presenting the respective conclusions. (author)

  3. Utilization of the IAIA (Investigation and Analysis of Incidents and Accidents) method in the investigation of the P-36 platform accident; Utilizacao do metodo IAIA (Investigacao e Analise de Acidentes e Incidentes) na investigacao do acidente ocorrido na plataforma P-36

    Energy Technology Data Exchange (ETDEWEB)

    Teles, Marcus de Barros [ARCE - Agencia Reguladora de Servicos Publicos Delegados do Estado do Ceara, Fortaleza, CE (Brazil)

    2004-07-01

    In the beginning of XXI century the Brazilian oil industry report a big accident involving that which was the biggest petroleum platform of the world. With capacity production of 180.000 barrels a day and capacity compression of 7,2 million cubic meter a day of natural gas, the off-shore platform P-36 was situated on Roncador field, in Campos basin, operating in 1360 meters of water. As consequences, eleven deaths with irreparable traumas to the families, friends and worker partners, one billion dollars in prejudices to brazilian country, environmental damages by oil leak and injuries to PETROBRAS reputation in Brazil and in the world. The method of investigation and analysis of incidents and accidents - IAIA is very wide and its philosophy contain a lot of topics, since basic concepts, investigation actions, analysis action and diagnosis by the general kind of fail. Using this method and taking advantage from the report elaborated by the commission organized by ANP - Agencia Nacional do Petroleo and DPC - Diretoria de Portos e Costas, responsible for the investigation and analysis of the accident occurred with P-36, this paper identify the direct and indirect causes of the accident, in attempt to avoid new similar situations. (author)

  4. Improved Digital Image Correlation method

    Science.gov (United States)

    Mudassar, Asloob Ahmad; Butt, Saira

    2016-12-01

    Digital Image Correlation (DIC) is a powerful technique which is used to correlate two image segments to determine the similarity between them. A correlation image is formed which gives a peak known as correlation peak. If the two image segments are identical the peak is known as auto-correlation peak otherwise it is known as cross correlation peak. The location of the peak in a correlation image gives the relative displacement between the two image segments. Use of DIC for in-plane displacement and deformation measurements in Electronic Speckle Photography (ESP) is well known. In ESP two speckle images are correlated using DIC and relative displacement is measured. We are presenting background review of ESP and disclosing a technique based on DIC for improved relative measurements which we regard as the improved DIC method. Simulation and experimental results reveal that the proposed improved-DIC method is superior to the conventional DIC method in two aspects, in resolution and in the availability of reference position in displacement measurements.

  5. Global Method for Electron Correlation

    Science.gov (United States)

    Piris, Mario

    2017-08-01

    The current work presents a new single-reference method for capturing at the same time the static and dynamic electron correlation. The starting point is a determinant wave function formed with natural orbitals obtained from a new interacting-pair model. The latter leads to a natural orbital functional (NOF) capable of recovering the complete intrapair, but only the static interpair correlation. Using the solution of the NOF, two new energy functionals are defined for both dynamic (Edyn) and static (Esta) correlation. Edyn is derived from a modified second-order Møller-Plesset perturbation theory (MP2), while Esta is obtained from the static component of the new NOF. Double counting is avoided by introducing the amount of static and dynamic correlation in each orbital as a function of its occupation. As a result, the total energy is represented by the sum E˜ HF+Edyn+Esta , where E˜ HF is the Hartree-Fock energy obtained with natural orbitals. The new procedure called NOF-MP2 scales formally as O (M5) (where M is the number of basis functions), and is applied successfully to the homolytic dissociation of a selected set of diatomic molecules, paradigmatic cases of near-degeneracy effects. The size consistency has been numerically demonstrated for singlets. The values obtained are in good agreement with the experimental data.

  6. Strongly correlated systems numerical methods

    CERN Document Server

    Mancini, Ferdinando

    2013-01-01

    This volume presents, for the very first time, an exhaustive collection of those modern numerical methods specifically tailored for the analysis of Strongly Correlated Systems. Many novel materials, with functional properties emerging from macroscopic quantum behaviors at the frontier of modern research in physics, chemistry and material science, belong to this class of systems. Any technique is presented in great detail by its own inventor or by one of the world-wide recognized main contributors. The exposition has a clear pedagogical cut and fully reports on the most relevant case study where the specific technique showed to be very successful in describing and enlightening the puzzling physics of a particular strongly correlated system. The book is intended for advanced graduate students and post-docs in the field as textbook and/or main reference, but also for other researchers in the field who appreciate consulting a single, but comprehensive, source or wishes to get acquainted, in a as painless as possi...

  7. Application of the perturbed angular correlation in the investigation of hyperfine interactions in compounds of hafnium, indium and cadmium with F{sup 1-}, OH{sup 1-} and EDTA ligands; Aplicacao da espectroscopia de correlacao angular perturbada na investigacao de interacoes hiperfinas em compostos de hafnio, indio e cadmio com os ligantes F{sup 1-}, OH{sup 1-} e EDTA

    Energy Technology Data Exchange (ETDEWEB)

    Amaral, Antonio Acleto

    2011-07-01

    In this study the hyperfine parameters, including the dynamical nature, Perturbed Angular Correlation (PAC) spectroscopy was used to measure the hyperfine parameters in molecules of ligand compounds in solutions. The measurements were carried out at 295 K and 77 K using {sup 111}In {yields} {sup 111}Cd, {sup 181}Hf {yields} {sup 181}Ta and {sup 111m}Cd {yields}{sup 111}Cd, as probe nuclei. Samples were prepared by adding a small volume of radioactive solution containing the probe nuclei in aqueous solution, buffer solution and ethylenediaminetetraacetic acid (EDTA) used as a ligand with pH 4.3 which correspond to the pH of the saturated EDTA solution and in buffer solution with pH between 9 and 10. The results made possible to understand the impact of each method for PAC measurements. Finally a comparative analysis for the several methods of inserting of the probe nuclei in the sample was made, considering chemical and nuclear aspects. The lack of measurements in this kind of samples justifies the importance of the obtained results. (author)

  8. Correlation methods in cutting arcs

    Energy Technology Data Exchange (ETDEWEB)

    Prevosto, L; Kelly, H, E-mail: prevosto@waycom.com.ar [Grupo de Descargas Electricas, Departamento Ing. Electromecanica, Universidad Tecnologica Nacional, Regional Venado Tuerto, Laprida 651, Venado Tuerto (2600), Santa Fe (Argentina)

    2011-05-01

    The present work applies similarity theory to the plasma emanating from transferred arc, gas-vortex stabilized plasma cutting torches, to analyze the existing correlation between the arc temperature and the physical parameters of such torches. It has been found that the enthalpy number significantly influence the temperature of the electric arc. The obtained correlation shows an average deviation of 3% from the temperature data points. Such correlation can be used, for instance, to predict changes in the peak value of the arc temperature at the nozzle exit of a geometrically similar cutting torch due to changes in its operation parameters.

  9. Investigation of hyperfine interactions in DNA and antibody of different lineages of mice infected by T. cruzi by perturbed gamma-gamma angular correlation spectroscopy; Investigacao de interacoes hiperfinas em DNA e anticorpos de diferentes linhagens de camundongos frente a infeccao por T. cruzi pela epectroscopia de correlacao angular gama-gama perturbada

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Andreia dos Santos

    2012-07-01

    In the present work perturbed angular correlation (PAC) spectroscopy was used to measured electric quadrupole interactions in DNA biomolecules of different mice lineages (A/J, C57BL/6, B6AF1, BXA1 e BXA2), samples of different isotypes of immunoglobulin G (IgG1, IgG2a e IgG2b) and active portions of complete and fragmented immunoglobulin responsible by the immune response. Electric quadrupole interactions were also measured in DNA nitrogenous bases (adenine, cytosine, guanine, thymine). PAC measurements were performed using {sup 111}In {yields} {sup 111C}d; {sup 111mC}d {yields} {sup 111}Cd; {sup 111}Ag {yields} {sup 111}Cd; e {sup 181}Hf {yields} {sup 181}Ta as probe nuclei, and carried out at room temperature and liquid nitrogen temperature, in order to investigate dynamic and static hyperfine interactions, respectively. The biomolecule samples were directly marked with the radioactive parent nuclei, whose atom link to a certain site in the biomolecules. The biological materials as well as the probe nuclei were chosen to investigate the possibility to use PAC spectroscopy to measure hyperfine parameters at nuclei from metallic elements bound to biomolecules (including the use of different probe nuclei produced in the decay of parent nuclei of four different metals) and also to study the behavior of different biomolecules by means of the measured hyperfine parameters. Results show differences in the hyperfine interactions of probe nuclei bound to the studied biomolecules. Such differences were observed by variations in the hyperfine parameters, which depend on the type of biomolecule and the results also show that the probe nuclei atom bound to the molecule in some cases and in others do not. (author)

  10. Investigation of local magnetism in RZn (R = Ce, Gd, Tb, Dy) and GdCu intermetallic compounds using perturbed angular correlation gamma-gamma spectroscopy; Investigacao do magnetismo local em compostos intermetalicos do tipo RZn (R = Ce, Gd, Tb, Dy) e GdCu pela espectroscopia de correlacao angular gama-gama perturbada

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Brianna Bosch dos

    2010-07-01

    This work presents, from a microscopic point of view, a systematic study of the local magnetism in RZn (R = Ce, Gd, Tb, Dy) and GdCu intermetallic compounds through measurements of hyperfine interactions using the Perturbed Angular Correlation Gamma- Gamma Spectroscopy technique with {sup 111}In {yields} {sup 111}Cd and {sup 140}La {yields} {sup 140}Ce as probe nuclei. As the magnetism in these compounds originates from the 4f electrons of the rare-earth elements it is interesting to observe in a systematic study of RZn compounds the behavior of the magnetic hyperfine field with the variation of the number of 4f electrons in the R element. The use of probe nuclei {sup 140}La {yields} {sup 140}Ce is interesting because Ce{sup +3} ion posses one 4f electron which may contribute to the total hyperfine field, and the results showed anomalous behavior. The results for {sup 111}Cd probe showed that the temperature dependence of the magnetic hyperfine field follows the Brillouin function, and the magnetic hyperfine field decreases linearly with increase of the atomic number of rare earth when plotted as a function of the rare-earth J spin projection, showing that the main contribution to the magnetic hyperfine field in RZn compounds comes from the polarization of the conduction electrons. The results for the electric field gradient measured with {sup 111}Cd for all compounds showed a strong decrease with the atomic number of the rare-earth element. We have therefore assumed that the major contribution to the electric field gradient originates from the 4f electrons of the rare-earths. The measurements of the electric field gradient for GdCu with {sup 111}Cd, after temperature decreases and increases again showed that two different structures, CsCl-type cubic and FeB-type orthorhombic structures co-exist. Finally, it is the first time that measurements of hyperfine parameters have been carried out with theses two probe nuclei in the studied RZn. (author)

  11. A method for generating realistic correlation matrices

    CERN Document Server

    Garcia, Stephan Ramon

    2011-01-01

    Simulating sample correlation matrices is important in many areas of statistics. Approaches such as generating normal data and finding their sample correlation matrix or generating random uniform $[-1,1]$ deviates as pairwise correlations both have drawbacks. We develop an algorithm for adding noise, in a highly controlled manner, to general correlation matrices. In many instances, our method yields results which are superior to those obtained by simply simulating normal data. Moreover, we demonstrate how our general algorithm can be tailored to a number of different correlation models. Finally, using our results with an existing clustering algorithm, we show that simulating correlation matrices can help assess statistical methodology.

  12. BONNSAI: correlated stellar observables in Bayesian methods

    CERN Document Server

    Schneider, F R N; Fossati, L; Langer, N; de Koter, A

    2016-01-01

    In an era of large spectroscopic surveys of stars and big data, sophisticated statistical methods become more and more important in order to infer fundamental stellar parameters such as mass and age. Bayesian techniques are powerful methods because they can match all available observables simultaneously to stellar models while taking prior knowledge properly into account. However, in most cases it is assumed that observables are uncorrelated which is generally not the case. Here, we include correlations in the Bayesian code BONNSAI by incorporating the covariance matrix in the likelihood function. We derive a parametrisation of the covariance matrix that, in addition to classical uncertainties, only requires the specification of a correlation parameter that describes how observables co-vary. Our correlation parameter depends purely on the method with which observables have been determined and can be analytically derived in some cases. This approach therefore has the advantage that correlations can be accounte...

  13. BONNSAI: correlated stellar observables in Bayesian methods

    Science.gov (United States)

    Schneider, F. R. N.; Castro, N.; Fossati, L.; Langer, N.; de Koter, A.

    2017-02-01

    In an era of large spectroscopic surveys of stars and big data, sophisticated statistical methods become more and more important in order to infer fundamental stellar parameters such as mass and age. Bayesian techniques are powerful methods because they can match all available observables simultaneously to stellar models while taking prior knowledge properly into account. However, in most cases it is assumed that observables are uncorrelated which is generally not the case. Here, we include correlations in the Bayesian code Bonnsai by incorporating the covariance matrix in the likelihood function. We derive a parametrisation of the covariance matrix that, in addition to classical uncertainties, only requires the specification of a correlation parameter that describes how observables co-vary. Our correlation parameter depends purely on the method with which observables have been determined and can be analytically derived in some cases. This approach therefore has the advantage that correlations can be accounted for even if information for them are not available in specific cases but are known in general. Because the new likelihood model is a better approximation of the data, the reliability and robustness of the inferred parameters are improved. We find that neglecting correlations biases the most likely values of inferred stellar parameters and affects the precision with which these parameters can be determined. The importance of these biases depends on the strength of the correlations and the uncertainties. For example, we apply our technique to massive OB stars, but emphasise that it is valid for any type of stars. For effective temperatures and surface gravities determined from atmosphere modelling, we find that masses can be underestimated on average by 0.5σ and mass uncertainties overestimated by a factor of about 2 when neglecting correlations. At the same time, the age precisions are underestimated over a wide range of stellar parameters. We conclude that

  14. FUNCTIONAL CORRELATION OF FP AND DC METHODS

    Directory of Open Access Journals (Sweden)

    Marin Kaluža

    2013-02-01

    Full Text Available Most of organizations today use information-communication technologies (ICT for building an information system (IS. IS is assembled of hardware, software, network resources, organizational and human resources. In IS development process, complexity is crucial for evaluating quantities of resources needed (time, people, money, equipment. Complexity of an IS can be evaluated and/or measured in different phases of development. There are many methods for measuring complexity, but mostly used and thoroughly described method is Function Point Analysis (FP. The opposite method, Database Complexity (DC, does not measure all the aspects of IS, but it could evaluate system complexity depending on the database complexity. DC method is intended to be used for measuring semantic complexity of the IS database, and can be shown by counting attributes A and foreign keys F. This paper describes a very high correlation between FP and DC methods, and defines a function which can in 95% of accuracy express FP values from measured DC values.

  15. Jealousy: novel methods and neural correlates.

    Science.gov (United States)

    Harmon-Jones, Eddie; Peterson, Carly K; Harris, Christine R

    2009-02-01

    Because of the difficulties surrounding the evocation of jealousy, past research has relied on reactions to hypothetical scenarios and recall of past experiences of jealousy. Both methodologies have limitations, however. The present research was designed to develop a method of evoking jealousy in the laboratory that would be well controlled, ethically permissible, and psychologically meaningful. Study 1 demonstrated that jealousy could be evoked in a modified version of K. D. Williams' (2007) Cyberball ostracism paradigm in which the rejecting person was computer-generated. Study 2, the first to examine neural activity during the active experience of jealousy, tested whether experienced jealousy was associated with greater relative left or right frontal cortical activation. The findings revealed that the experience of jealousy was correlated with greater relative left frontal cortical activation toward the "sexually" desired partner. This pattern of activation suggests that jealousy is associated with approach motivation. Taken together, the present studies developed a laboratory paradigm for the study of jealousy that should help foster research on one of the most social of emotions.

  16. Ergodicity test of the eddy correlation method

    Science.gov (United States)

    Chen, J.; Hu, Y.; Yu, Y.; Lü, S.

    2014-07-01

    The turbulent flux observation in the near-surface layer is a scientific issue which researchers in the fields of atmospheric science, ecology, geography science, etc. are commonly interested in. For eddy correlation measurement in the atmospheric surface layer, the ergodicity of turbulence is a basic assumption of the Monin-Obukhov (M-O) similarity theory, which is confined to steady turbulent flow and homogenous surface; this conflicts with turbulent flow under the conditions of complex terrain and unsteady, long observational period, which the study of modern turbulent flux tends to focus on. In this paper, two sets of data from the Nagqu Station of Plateau Climate and Environment (NaPlaCE) and the cooperative atmosphere-surface exchange study 1999 (CASE99) were used to analyze and verify the ergodicity of turbulence measured by the eddy covariance system. Through verification by observational data, the vortex of atmospheric turbulence, which is smaller than the scale of the atmospheric boundary layer (i.e., its spatial scale is less than 1000 m and temporal scale is shorter than 10 min) can effectively meet the conditions of the average ergodic theorem, and belong to a wide sense stationary random processes. Meanwhile, the vortex, of which the spatial scale is larger than the scale of the boundary layer, cannot meet the conditions of the average ergodic theorem, and thus it involves non-ergodic stationary random processes. Therefore, if the finite time average is used to substitute for the ensemble average to calculate the average random variable of the atmospheric turbulence, then the stationary random process of the vortex, of which spatial scale was less than 1000 m and thus below the scale of the boundary layer, was possibly captured. However, the non-ergodic random process of the vortex, of which the spatial scale was larger than that of the boundary layer, could not be completely captured. Consequently, when the finite time average was used to substitute

  17. Correlation methods in fingerprint detection studies

    Energy Technology Data Exchange (ETDEWEB)

    Santer, B.D.; Wigley, T.M.L.; Jones, P.D. (Lawrence Livermore National Laboratory, Livermore, CA (United States))

    1993-07-01

    This investigation addresses two general issues regarding the role of pattern similarity statistics in greenhouse warming detection studies: normalization, and the relative merits of centered versus uncentered statistics. A pattern correlation statistic is used to search for the greenhouse warming signals predicted by five different models in the observed records of land and ocean surface temperature changes. Two forms of this statistic were computed: R(t), which makes use of non-normalized data, and R(t), which employs point-wise normalized data in order to focus the search on regions where the signal-to-noise ratio is large. While there are no trends in the R(t) time series, the time series of R(t) show large positive trends. However, it is not possible to infer from the R(t) results that the observed pattern of temperature change is, in fact, becoming increasingly similar to the model-predicted signal. It is shown that trends in R(t) must arise almost completely from the observed data, and cannot be an indicator of increasing observed data/signal similarity. The most informative pattern correlation statistic for detection purposes is R(t), the standard product-moment correlation coefficient between the observed and model fields. Our failure to find meaningful trends in R(t) may be due to the fact that the signal is being obscured by the background noise of natural variability, and/or because of incorrect model signals or sensitivities.

  18. Bin-bin correlation measurement by bunching-parameter method

    Energy Technology Data Exchange (ETDEWEB)

    Chekanov, S.V.; Kittel, W. [High Energy Physics Inst. Nijmegen, Univ. of Nijmegen/NIKHEF, Nijmegen (Netherlands); Kuvshinov, V.I. [Inst. of Physics, Academy of Sciences of Belarus, Minsk (Belgium)

    1996-08-01

    A new method for the experimental study of bin-bin correlations is proposed. It is shown that this method is able to reveal important additional information on bin-bin correlations, beyond that of factorial-correlator measurements. (author) 15 refs, 1 fig

  19. Correlation studies on surface particle detection methods

    Science.gov (United States)

    Peterson, Ronald V.; White, James C.

    1988-01-01

    The accurate determination of dust levels on optical surfaces is necessary to assess sensor system performance. A comparison study was made on several particle measurement methods including those based on direct imaging and light scattering. The effectiveness of removing the particles from the surface prior to determining particle size distributions was also assessed. These studies revealed that some methods, especially those requiring particle removal before analysis, are subject to large systematic errors affecting particle size distributions. Thus, an understanding of the particle measurement methods employed is necessary before any surface cleanliness or obstruction value assignments are accepted as true representations of an optical surface contamination condition.

  20. Relativistic internally contracted multireference electron correlation methods

    CERN Document Server

    Shiozaki, Toru

    2015-01-01

    We report internally contracted relativistic multireference configuration interaction (ic-MRCI), complete active space second-order perturbation (CASPT2), and strongly contracted n-electron valence state perturbation theory (NEVPT2) on the basis of the four-component Dirac Hamiltonian, enabling accurate simulations of relativistic, quasi-degenerate electronic structure of molecules containing transition-metal and heavy elements. Our derivation and implementation of ic-MRCI and CASPT2 are based on an automatic code generator that translates second-quantized ans\\"atze to tensor-based equations, and to efficient computer code. NEVPT2 is derived and implemented manually. The rovibrational transition energies and absorption spectra of HI and TlH are presented to demonstrate the accuracy of these methods.

  1. A MONTE-CARLO METHOD FOR ESTIMATING THE CORRELATION EXPONENT

    NARCIS (Netherlands)

    MIKOSCH, T; WANG, QA

    1995-01-01

    We propose a Monte Carlo method for estimating the correlation exponent of a stationary ergodic sequence. The estimator can be considered as a bootstrap version of the classical Hill estimator. A simulation study shows that the method yields reasonable estimates.

  2. A MONTE-CARLO METHOD FOR ESTIMATING THE CORRELATION EXPONENT

    NARCIS (Netherlands)

    MIKOSCH, T; WANG, QA

    We propose a Monte Carlo method for estimating the correlation exponent of a stationary ergodic sequence. The estimator can be considered as a bootstrap version of the classical Hill estimator. A simulation study shows that the method yields reasonable estimates.

  3. Correlations between direct and indirect strength test methods

    Institute of Scientific and Technical Information of China (English)

    Kallu Raj; Roghanchi Pedram

    2015-01-01

    The difficulties associated with performing direct compression strength tests on rocks lead to the devel-opment of indirect test methods for the rock strength assessment. Indirect test methods are simple, more economical, less time-consuming, and easily adaptable to the field. The main aim of this study was to derive correlations between direct and indirect test methods for basalt and rhyolite rock types from Carlin trend deposits in Nevada. In the destructive methods, point load index, block punch index, and splitting tensile strength tests are performed. In the non-destructive methods, Schmidt hammer and ultrasonic pulse velocity tests are performed. Correlations between the direct and indirect compression strength tests are developed using linear and nonlinear regression analysis methods. The results show that the splitting tensile strength has the best correlation with the uniaxial compression strength. Furthermore, the Poisson’s ratio has no correlation with any of the direct and indirect test results.

  4. An Improved Dynamic Programming Method for Automatic Stratigraphic Correlation

    Institute of Scientific and Technical Information of China (English)

    Yan Hanjie; Yan Hong; Xiang Zhucong; Wang Yanjiang

    2003-01-01

    An improved dynamic programming algorithm is proposed for reducing the possible mismatching of layer in multi-well correlation. Compared with the standard dynamic programming algorithm, this method restricts the searching range during layer matching. It can not only avoid possible mismatching between sample and target layer, but also reduce the time spent on layer correlation. The result of applying the improved methods on the data processed by standard method before indicates that the improved one is more effective and timesaving for the multi-well correlation system than conventional dynamic programming algorithm.

  5. Correlation theory-based signal processing method for CMF signals

    Science.gov (United States)

    Shen, Yan-lin; Tu, Ya-qing

    2016-06-01

    Signal processing precision of Coriolis mass flowmeter (CMF) signals affects measurement accuracy of Coriolis mass flowmeters directly. To improve the measurement accuracy of CMFs, a correlation theory-based signal processing method for CMF signals is proposed, which is comprised of the correlation theory-based frequency estimation method and phase difference estimation method. Theoretical analysis shows that the proposed method eliminates the effect of non-integral period sampling signals on frequency and phase difference estimation. The results of simulations and field experiments demonstrate that the proposed method improves the anti-interference performance of frequency and phase difference estimation and has better estimation performance than the adaptive notch filter, discrete Fourier transform and autocorrelation methods in terms of frequency estimation and the data extension-based correlation, Hilbert transform, quadrature delay estimator and discrete Fourier transform methods in terms of phase difference estimation, which contributes to improving the measurement accuracy of Coriolis mass flowmeters.

  6. WAVELET BASED SPECTRAL CORRELATION METHOD FOR DPSK CHIP RATE ESTIMATION

    Institute of Scientific and Technical Information of China (English)

    Li Yingxiang; Xiao Xianci; Tai Hengming

    2004-01-01

    A wavelet-based spectral correlation algorithm to detect and estimate BPSK signal chip rate is proposed. Simulation results show that the proposed method can correctly estimate the BPSK signal chip rate, which may be corrupted by the quadratic characteristics of the spectral correlation function, in a low SNR environment.

  7. A double-correlation tremor-location method

    CERN Document Server

    Li, Ka Lok; Sadeghisorkhani, Hamzeh; Roberts, Roland; Gudmundsson, Ólafur

    2016-01-01

    A double-correlation method is introduced to locate tremor sources based on stacks of complex, doubly-correlated tremor records of multiple triplets of seismographs back projected to hypothetical source locations in a geographic grid. Peaks in the resulting stack of moduli are inferred source locations. The stack of the moduli is a robust measure of energy radiated from a point source or point sources even when the velocity information is imprecise. Application to real data shows how double correlation focuses the source mapping compared to the common single correlation approach. Synthetic tests demonstrate the robustness of the method and its resolution limitations which are controlled by the station geometry, the finite frequency of the signal, the quality of the used velocity information and noise level. Both random noise and signal or noise correlated at time shifts that are inconsistent with the assumed velocity structure can be effectively suppressed. Assuming a surface-wave velocity, we can constrain t...

  8. Dermatoglyphics: Correlation between software and traditional method in kineanthropometric application

    Directory of Open Access Journals (Sweden)

    R.J. Nodari-Júnior

    2014-06-01

    Conclusion: These results significantly correlate the computerized and traditional methods, which qualifies M1 as the instrument for the capture, structuration of the design and analysis of the digital fingerprints through a dermatoglyphic method using the digital fingerprint marker, which is the essential condition to acceptance and scientific recognition of new instruments.

  9. Rapid Measurement of Spectral Characteristics by Correlation Matching Method

    CERN Document Server

    Kim, Chol-Sun; Im, Song-Jin

    2015-01-01

    In this paper, we have established the couple system of a spectroscope, CCD and computer and proposed a method of the rapid measurement on spectral characteristics such as central wavelengths, relative intensities, sensitivity lines and the wavelength range and image pixel of the spectral images of a material by using the correlation matching method for the image discernment of digital spectra.

  10. A correlation method of detecting and estimating interactions of QTLs

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    More and more studies demonstrate that a great deal of interactions among the quantitative trait loci (QTLs) are far more than those detected by single markers. A correlation method was proposed for estimating the interactions of multiple QTLs detected by multi-markers in several mapping populations. Genetic implication of this method and usage were discussed.

  11. Bringing the cross-correlation method up to date

    Science.gov (United States)

    Statler, Thomas

    1995-03-01

    The cross-correlation (XC) method of Tonry & Davis (1979, AJ, 84, 1511) is generalized to arbitrary parametrized line profiles. In the new algorithm the correlation function itself, rather than the observed galaxy spectrum, is fitted by the model line profile: this removes much of the complication in the error analysis caused by template mismatch. Like the Fourier correlation quotient (FCQ) method of Bender (1990, A&A, 229, 441), the inferred line profiles are, up to a normalization constant, independent of template mismatch as long as there are no blended lines. The standard reduced chi2 is a good measure of the fit of the inferred velocity distribution, largely decoupled from the fit of the spectral template. The updated XC method performs as well as other recently developed methods, with the added virtue of conceptual simplicity.

  12. Bringing the cross-correlation method up to date

    Science.gov (United States)

    Statler, Thomas

    1995-01-01

    The cross-correlation (XC) method of Tonry & Davis (1979, AJ, 84, 1511) is generalized to arbitrary parametrized line profiles. In the new algorithm the correlation function itself, rather than the observed galaxy spectrum, is fitted by the model line profile: this removes much of the complication in the error analysis caused by template mismatch. Like the Fourier correlation quotient (FCQ) method of Bender (1990, A&A, 229, 441), the inferred line profiles are, up to a normalization constant, independent of template mismatch as long as there are no blended lines. The standard reduced chi(exp 2) is a good measure of the fit of the inferred velocity distribution, largely decoupled from the fit of the spectral template. The updated XC method performs as well as other recently developed methods, with the added virtue of conceptual simplicity.

  13. A Parallel Probabilistic Load Flow Method Considering Nodal Correlations

    Directory of Open Access Journals (Sweden)

    Jun Liu

    2016-12-01

    Full Text Available With the introduction of more and more random factors in power systems, probabilistic load flow (PLF has become one of the most important tasks for power system planning and operation. Cumulants-based PLF is an effective algorithm to calculate PLF in an analytical way, however, the correlations among the nodal injections to the system level have rarely been studied. A novel parallel cumulants-based PLF method considering nodal correlations is proposed in this paper, which is able to deal with the correlations among all system nodes, and avoid the Jacobian matrix inversion in the traditional cumulants-based PLF as well. In addition, parallel computing is introduced to improve the efficiency of the numerical calculations. The accuracy of the proposed method is validated by numerical tests on the standard IEEE-14 system, comparing with the results from Correlation Latin hypercube sampling Monte Carlo Simulation (CLMCS method. And the efficiency and parallel performance is proven by the tests on the modified IEEE-300, C703, N1047 systems with distributed generation (DG. Numerical simulations show that the proposed parallel cumulants-based PLF method considering nodal correlations is able to get more accurate results using less computational time and physical memory, and have higher efficiency and better parallel performance than the traditional one.

  14. Shape determination of unidimensional objects: the virtual image correlation method

    OpenAIRE

    Auradou H.; Vatteville J.; Semin B.; Francois M.

    2010-01-01

    The proposed method, named Virtual Image Correlation, allows one to identify an analytical expression of the shape of a curvilinear object from its image. It uses a virtual beam, whose curvature field is expressed as a truncated mathematical series. The virtual beam width only needs to be close to the physical one; its gray level (in the transverse direction) is bell-shaped. The method consists in finding the coefficients of the series for which the correlation between physical and virtual ...

  15. Systematic errors in the correlation method for Johnson noise thermometry: residual correlations due to amplifiers

    CERN Document Server

    Callegaro, Luca; Ortolano, Massimo

    2009-01-01

    Johnson noise thermometers (JNT) measure the equilibrium electrical noise, proportional to thermodynamic temperature, of a sensing resistor. In the correlation method, the same resistor is connected to two amplifiers and a correlation of their outputs is performed, in order to reject amplifiers' noise. Such rejection is not perfect: the residual correlation gives a systematic error in the JNT reading. In order to put an upper limit, or to achieve a correction, for such error, a careful electrical modelling of the amplifiers and connections must be performed. Standard numerical simulation tools are inadequate for such modelling. In literature, evaluations have been performed by the painstaking solving of analytical modelling. We propose an evaluation procedure for the JNT error due to residual correlations which blends analytical and numerical approaches, with the benefits of both: a rigorous and accurate circuit noise modelling, and a fast and flexible evaluation with an user-friendly commercial tool. The met...

  16. DIGITAL SPECKLE CORRELATION METHOD IMPROVED BY GENETIC ALGORITHM

    Institute of Scientific and Technical Information of China (English)

    MaShaopeng; JillGuanchang

    2003-01-01

    The digital speckle correlation method is an important optical metrology for surface displacement and strain measurement. With this technique, the whole field deformation information can be obtained by tracking the geometric points on the speckle images based on a correlation-matching search technique. However, general search techniques suffer from great computational complexity in the processing of speckle images with large deformation and the large random errors in the processing of images of bad quality. In this paper, an advanced approach based on genetic algorithms (GA) for correlation-matching search is developed. Benefiting from the abilities of global optimum and parallelism searching of GA, this new approach can complete the correlation-matching search with less computational consumption and at high accuracy. Two experimental results from the simulated speckle images have proved the efficiency of the new approach.

  17. A double-correlation tremor-location method

    Science.gov (United States)

    Li, Ka Lok; Sgattoni, Giulia; Sadeghisorkhani, Hamzeh; Roberts, Roland; Gudmundsson, Olafur

    2017-02-01

    A double-correlation method is introduced to locate tremor sources based on stacks of complex, doubly-correlated tremor records of multiple triplets of seismographs back projected to hypothetical source locations in a geographic grid. Peaks in the resulting stack of moduli are inferred source locations. The stack of the moduli is a robust measure of energy radiated from a point source or point sources even when the velocity information is imprecise. Application to real data shows how double correlation focuses the source mapping compared to the common single correlation approach. Synthetic tests demonstrate the robustness of the method and its resolution limitations which are controlled by the station geometry, the finite frequency of the signal, the quality of the used velocity information and noise level. Both random noise and signal or noise correlated at time shifts that are inconsistent with the assumed velocity structure can be effectively suppressed. Assuming a surface wave velocity, we can constrain the source location even if the surface wave component does not dominate. The method can also in principle be used with body waves in 3-D, although this requires more data and seismographs placed near the source for depth resolution.

  18. Capturing correlations in chaotic diffusion by approximation methods.

    Science.gov (United States)

    Knight, Georgie; Klages, Rainer

    2011-10-01

    We investigate three different methods for systematically approximating the diffusion coefficient of a deterministic random walk on the line that contains dynamical correlations that change irregularly under parameter variation. Capturing these correlations by incorporating higher-order terms, all schemes converge to the analytically exact result. Two of these methods are based on expanding the Taylor-Green-Kubo formula for diffusion, while the third method approximates Markov partitions and transition matrices by using a slight variation of the escape rate theory of chaotic diffusion. We check the practicability of the different methods by working them out analytically and numerically for a simple one-dimensional map, study their convergence, and critically discuss their usefulness in identifying a possible fractal instability of parameter-dependent diffusion, in the case of dynamics where exact results for the diffusion coefficient are not available.

  19. Cluster-in-molecule local correlation method for large systems

    Institute of Scientific and Technical Information of China (English)

    LI Wei; LI ShuHua

    2014-01-01

    A linear scaling local correlation method,cluster-in-molecule(CIM)method,was developed in the last decade for large systems.The basic idea of the CIM method is that the electron correlation energy of a large system,within the M ller-Plesset perturbation theory(MP)or coupled cluster(CC)theory,can be approximately obtained from solving the corresponding MP or CC equations of various clusters.Each of such clusters consists of a subset of localized molecular orbitals(LMOs)of the target system,and can be treated independently at various theory levels.In the present article,the main idea of the CIM method is reviewed,followed by brief descriptions of some recent developments,including its multilevel extension and different ways of constructing clusters.Then,some applications for large systems are illustrated.The CIM method is shown to be an efficient and reliable method for electron correlation calculations of large systems,including biomolecules and supramolecular complexes.

  20. Two-Dimensional Correlation Method for Polymer Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Herman, Matthew Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-06-08

    Since its introduction by Noda in 1986 two-dimension correlation spectroscopy has been offering polymer scientists an opportunity to look more deeply into collected spectroscopic data. When the spectra are recorded in response to an external perturbation, it is possible to correlate the spectra and expand the information over a separate spectra axis allow for enhancement of spectral resolution, the ability to determine synchronous change, and a unique way to organize observed changes in the spectra into sequential order following a set of three simple rules. By organizing the 2D spectra into synchronous change plots and asynchronous change plots it is possible to correlate change between spectral regions and develop their temporal relationships to one another. With the introduction of moving-window correlation-spectroscopy by Thomas and Richardson in 2000, a method of binning and processing data, it became possible to directly correlate relationships generated in the spectra from the change in the perturbation variable. This method takes advantage of the added resolution of two-dimension spectroscopy and has been applied to study very week transitions found in polymer materials. Appling both of these techniques we are beginning to develop an understanding of how polymers decay under radiolytic aging, to develop a stronger understanding of changes in mechanical properties and the service capabilities of materials.

  1. External Source Method for Kubo-Transformed Quantum Correlation Functions

    CERN Document Server

    Horikoshi, Atsushi

    2014-01-01

    We revisit the external source method for Kubo-transformed quantum correlation functions recently proposed by Krishna and Voth. We derive an exact formula and show that the Krishna-Voth formula can be derived as an approximation of our formula. Some properties of this approximation are clarified through a model calculation of the position autocorrelation function for a one-dimensional harmonic oscillator. A key observation is that the Krishna-Voth correlation function has a term which behaves as the secular term in perturbation theory.

  2. Shape determination of unidimensional objects: the virtual image correlation method

    Directory of Open Access Journals (Sweden)

    Auradou H.

    2010-06-01

    Full Text Available The proposed method, named Virtual Image Correlation, allows one to identify an analytical expression of the shape of a curvilinear object from its image. It uses a virtual beam, whose curvature field is expressed as a truncated mathematical series. The virtual beam width only needs to be close to the physical one; its gray level (in the transverse direction is bell-shaped. The method consists in finding the coefficients of the series for which the correlation between physical and virtual beams is the best. The accuracy and the robustness of the method is shown by the mean of two examples. The first details a Young’s modulus identification from a cantilever beam image. The second is relative to a thermal plume image, that have a weak contrast and a lot of noise.

  3. Shape determination of unidimensional objects: the virtual image correlation method

    Science.gov (United States)

    Francois, M.; Semin, B.; Auradou, H.; Vatteville, J.

    2010-06-01

    The proposed method, named Virtual Image Correlation, allows one to identify an analytical expression of the shape of a curvilinear object from its image. It uses a virtual beam, whose curvature field is expressed as a truncated mathematical series. The virtual beam width only needs to be close to the physical one; its gray level (in the transverse direction) is bell-shaped. The method consists in finding the coefficients of the series for which the correlation between physical and virtual beams is the best. The accuracy and the robustness of the method is shown by the mean of two examples. The first details a Young’s modulus identification from a cantilever beam image. The second is relative to a thermal plume image, that have a weak contrast and a lot of noise.

  4. An improved image reconstruction method for optical intensity correlation Imaging

    Science.gov (United States)

    Gao, Xin; Feng, Lingjie; Li, Xiyu

    2016-12-01

    The intensity correlation imaging method is a novel kind of interference imaging and it has favorable prospects in deep space recognition. However, restricted by the low detecting signal-to-noise ratio (SNR), it's usually very difficult to obtain high-quality image of deep space object like high-Earth-orbit (HEO) satellite with existing phase retrieval methods. In this paper, based on the priori intensity statistical distribution model of the object and characteristics of measurement noise distribution, an improved method of Prior Information Optimization (PIO) is proposed to reduce the ambiguous images and accelerate the phase retrieval procedure thus realizing fine image reconstruction. As the simulations and experiments show, compared to previous methods, our method could acquire higher-resolution images with less error in low SNR condition.

  5. New Transcorrelated Method Improving the Feasibility of Explicitly Correlated Calculations

    Directory of Open Access Journals (Sweden)

    Osamu Hino

    2002-05-01

    Full Text Available Abstract: We recently developed an explicitly correlated method using the transcorrelated Hamiltonian, which is preliminarily parameterized in such a way that the Coulomb repulsion is compensated at short inter-electronic distances. The extra part of the effective Hamiltonian features short-ranged, size-consistent, and state-universal. The localized and frozen nature of the correlation factor makes the enormous three-body interaction less important and enables us to bypass the complex nonlinear optimization. We review the basic strategy of the method mainly focusing on the applications to single-reference many electron theories using modified Møller-Plesset partitioning and biorthogonal orbitals. Benchmark calculations are performed for 10-electron systems with a series of basis sets.

  6. Correlation between two methods of florbetapir PET quantitative analysis.

    Science.gov (United States)

    Breault, Christopher; Piper, Jonathan; Joshi, Abhinay D; Pirozzi, Sara D; Nelson, Aaron S; Lu, Ming; Pontecorvo, Michael J; Mintun, Mark A; Devous, Michael D

    2017-01-01

    This study evaluated performance of a commercially available standardized software program for calculation of florbetapir PET standard uptake value ratios (SUVr) in comparison with an established research method. Florbetapir PET images for 183 subjects clinically diagnosed as cognitively normal (CN), mild cognitive impairment (MCI) or probable Alzheimer's disease (AD) (45 AD, 60 MCI, and 78 CN) were evaluated using two software processing algorithms. The research method uses a single florbetapir PET template generated by averaging both amyloid positive and amyloid negative registered brains together. The commercial software simultaneously optimizes the registration between the florbetapir PET images and three templates: amyloid negative, amyloid positive, and an average. Cortical average SUVr values were calculated across six predefined anatomic regions with respect to the whole cerebellum reference region. SUVr values were well correlated between the two methods (r2 = 0.98). The relationship between the methods computed from the regression analysis is: Commercial method SUVr = (0.9757*Research SUVr) + 0.0299. A previously defined cutoff SUVr of 1.1 for distinguishing amyloid positivity by the research method corresponded to 1.1 (95% CI = 1.098, 1.11) for the commercial method. This study suggests that the commercial method is comparable to the published research method of SUVr analysis for florbetapir PET images, thus facilitating the potential use of standardized quantitative approaches to PET amyloid imaging.

  7. A fast digital image correlation method for deformation measurement

    Science.gov (United States)

    Pan, Bing; Li, Kai

    2011-07-01

    Fast and high-accuracy deformation analysis using digital image correlation (DIC) has been increasingly important and highly demanded in recent years. In literature, the DIC method using the Newton-Rapshon (NR) algorithm has been considered as a gold standard for accurate sub-pixel displacement tracking, as it is insensitive to the relative deformation and rotation of the target subset and thus provides highest sub-pixel registration accuracy and widest applicability. A significant drawback of conventional NR-algorithm-based DIC method, however, is its extremely huge computational expense. In this paper, a fast DIC method is proposed deformation measurement by effectively eliminating the repeating redundant calculations involved in the conventional NR-algorithm-based DIC method. Specifically, a reliability-guided displacement scanning strategy is employed to avoid time-consuming integer-pixel displacement searching for each calculation point, and a pre-computed global interpolation coefficient look-up table is utilized to entirely eliminate repetitive interpolation calculation at sub-pixel locations. With these two approaches, the proposed fast DIC method substantially increases the calculation efficiency of the traditional NR-algorithm-based DIC method. The performance of proposed fast DIC method is carefully tested on real experimental images using various calculation parameters. Results reveal that the computational speed of the present fast DIC is about 120-200 times faster than that of the traditional method, without any loss of its measurement accuracy

  8. An improved method for estimating the frequency correlation function

    KAUST Repository

    Chelli, Ali

    2012-04-01

    For time-invariant frequency-selective channels, the transfer function is a superposition of waves having different propagation delays and path gains. In order to estimate the frequency correlation function (FCF) of such channels, the frequency averaging technique can be utilized. The obtained FCF can be expressed as a sum of auto-terms (ATs) and cross-terms (CTs). The ATs are caused by the autocorrelation of individual path components. The CTs are due to the cross-correlation of different path components. These CTs have no physical meaning and leads to an estimation error. We propose a new estimation method aiming to improve the estimation accuracy of the FCF of a band-limited transfer function. The basic idea behind the proposed method is to introduce a kernel function aiming to reduce the CT effect, while preserving the ATs. In this way, we can improve the estimation of the FCF. The performance of the proposed method and the frequency averaging technique is analyzed using a synthetically generated transfer function. We show that the proposed method is more accurate than the frequency averaging technique. The accurate estimation of the FCF is crucial for the system design. In fact, we can determine the coherence bandwidth from the FCF. The exact knowledge of the coherence bandwidth is beneficial in both the design as well as optimization of frequency interleaving and pilot arrangement schemes. © 2012 IEEE.

  9. Field methods to measure surface displacement and strain with the Video Image Correlation method

    Science.gov (United States)

    Maddux, Gary A.; Horton, Charles M.; Mcneill, Stephen R.; Lansing, Matthew D.

    1994-01-01

    The objective of this project was to develop methods and application procedures to measure displacement and strain fields during the structural testing of aerospace components using paint speckle in conjunction with the Video Image Correlation (VIC) system.

  10. a Task-Oriented Disaster Information Correlation Method

    Science.gov (United States)

    Linyao, Q.; Zhiqiang, D.; Qing, Z.

    2015-07-01

    With the rapid development of sensor networks and Earth observation technology, a large quantity of disaster-related data is available, such as remotely sensed data, historic data, case data, simulated data, and disaster products. However, the efficiency of current data management and service systems has become increasingly difficult due to the task variety and heterogeneous data. For emergency task-oriented applications, the data searches primarily rely on artificial experience based on simple metadata indices, the high time consumption and low accuracy of which cannot satisfy the speed and veracity requirements for disaster products. In this paper, a task-oriented correlation method is proposed for efficient disaster data management and intelligent service with the objectives of 1) putting forward disaster task ontology and data ontology to unify the different semantics of multi-source information, 2) identifying the semantic mapping from emergency tasks to multiple data sources on the basis of uniform description in 1), and 3) linking task-related data automatically and calculating the correlation between each data set and a certain task. The method goes beyond traditional static management of disaster data and establishes a basis for intelligent retrieval and active dissemination of disaster information. The case study presented in this paper illustrates the use of the method on an example flood emergency relief task.

  11. A TASK-ORIENTED DISASTER INFORMATION CORRELATION METHOD

    Directory of Open Access Journals (Sweden)

    Q. Linyao

    2015-07-01

    Full Text Available With the rapid development of sensor networks and Earth observation technology, a large quantity of disaster-related data is available, such as remotely sensed data, historic data, case data, simulated data, and disaster products. However, the efficiency of current data management and service systems has become increasingly difficult due to the task variety and heterogeneous data. For emergency task-oriented applications, the data searches primarily rely on artificial experience based on simple metadata indices, the high time consumption and low accuracy of which cannot satisfy the speed and veracity requirements for disaster products. In this paper, a task-oriented correlation method is proposed for efficient disaster data management and intelligent service with the objectives of 1 putting forward disaster task ontology and data ontology to unify the different semantics of multi-source information, 2 identifying the semantic mapping from emergency tasks to multiple data sources on the basis of uniform description in 1, and 3 linking task-related data automatically and calculating the correlation between each data set and a certain task. The method goes beyond traditional static management of disaster data and establishes a basis for intelligent retrieval and active dissemination of disaster information. The case study presented in this paper illustrates the use of the method on an example flood emergency relief task.

  12. Correlation Method for Public Security Information in Big Data Environment

    Directory of Open Access Journals (Sweden)

    Gang Zeng

    2015-04-01

    Full Text Available With the gradual improvement of the informationization level in public security area, the concept "Information led policing" has been formed, many information systems have been built and vast amounts of business data have been accumulated down, But these systems and data are isolated and becoming the isolated information islands. This thesis proposes an architecture of information analysis system on big data platform, then discuss the question of data integration, finally proposes the correlation method for public security information: direct association and indirect association.

  13. Fast methods for spatially correlated multilevel functional data

    KAUST Repository

    Staicu, A.-M.

    2010-01-19

    We propose a new methodological framework for the analysis of hierarchical functional data when the functions at the lowest level of the hierarchy are correlated. For small data sets, our methodology leads to a computational algorithm that is orders of magnitude more efficient than its closest competitor (seconds versus hours). For large data sets, our algorithm remains fast and has no current competitors. Thus, in contrast to published methods, we can now conduct routine simulations, leave-one-out analyses, and nonparametric bootstrap sampling. Our methods are inspired by and applied to data obtained from a state-of-the-art colon carcinogenesis scientific experiment. However, our models are general and will be relevant to many new data sets where the object of inference are functions or images that remain dependent even after conditioning on the subject on which they are measured. Supplementary materials are available at Biostatistics online.

  14. Study of quantum correlation swapping with relative entropy methods

    Science.gov (United States)

    Xie, Chuanmei; Liu, Yimin; Chen, Jianlan; Zhang, Zhanjun

    2016-02-01

    To generate long-distance shared quantum correlations (QCs) for information processing in future quantum networks, recently we proposed the concept of QC repeater and its kernel technique named QC swapping. Besides, we extensively studied the QC swapping between two simple QC resources (i.e., a pair of Werner states) with four different methods to quantify QCs (Xie et al. in Quantum Inf Process 14:653-679, 2015). In this paper, we continue to treat the same issue by employing other three different methods associated with relative entropies, i.e., the MPSVW method (Modi et al. in Phys Rev Lett 104:080501, 2010), the Zhang method (arXiv:1011.4333 [quant-ph]) and the RS method (Rulli and Sarandy in Phys Rev A 84:042109, 2011). We first derive analytic expressions of all QCs which occur during the swapping process and then reveal their properties about monotonicity and threshold. Importantly, we find that a long-distance shared QC can be generated from two short-distance ones via QC swapping indeed. In addition, we simply compare our present results with our previous ones.

  15. Deformation-phase measurement by digital speckle correlation method

    Science.gov (United States)

    Zhao, Ran; Sun, Ping

    2016-10-01

    A novel algorithm which extracts the out-of-plane component of deformation phase from two continuous fringe patterns is proposed. The velocity field between two consecutive frames is estimated by digital speckle correlation method (DSCM). After that, according to the optical flow constrained equation, the whole-field deformation-phase map is obtained by the estimations of the velocity field and the local frequency of the original image. The operation of the proposed method is simple compared with other phase demodulation methods. Moreover, the new method works perfectly at the areas with dense fringes. In this paper, the proposed algorithm is introduced. Meanwhile, in order to verify the effectiveness, the new algorithm is applied to simulated interferogram and real fringe pattern with a centrally loaded and edge-clamped plate. The results of simulation and experiment show that the new method can demodulate the out-of-plane component of deformation phase from the visible in-plane velocity field without unwrapping process. Further, dynamic deformation-phase extraction will be realized when we know the time interval of two continuous images. The proposed algorithm provides a new approach for whole-field deformation-phase measurement and dynamic deformation measurement.

  16. Explicitly Correlated Methods within the ccCA Methodology.

    Science.gov (United States)

    Mahler, Andrew; Wilson, Angela K

    2013-03-12

    The prediction of energetic properties within "chemical accuracy" (1 kcal mol(-1) from well-established experiment) can be a major challenge in computational quantum chemistry due to the computational requirements (computer time, memory, and disk space) needed to achieve this level of accuracy. Methodologies such as coupled cluster with single, double, and perturbative triple excitations (CCSD(T)) combined with very large basis sets are often required to reach this level of accuracy. Unfortunately, such calculations quickly become cost prohibitive as system size increases. Our group has developed an ab initio composite method, the correlation consistent Composite Approach (ccCA), which enables such accuracy to be possible, on average, but at reduced computational cost as compared with CCSD(T) in combination with a large basis set. While ccCA has proven quite useful, computational bottlenecks still occur. In this study, the means to reduce the computational cost of ccCA without compromising accuracy by utilizing explicitly correlated methods within ccCA have been considered, and an alternative formulation is described.

  17. Transforming han: a correlational method for psychology and religion.

    Science.gov (United States)

    Oh, Whachul

    2015-06-01

    Han is a destructive feeling in Korea. Although Korea accomplished significant exterior growth, Korean society is still experiencing the dark aspects of transforming han as evidenced by having the highest suicide rate in Asia. Some reasons for this may be the fragmentation between North and South Korea. If we can transform han then it can become constructive. I was challenged to think of possibilities for transforming han internally; this brings me to the correlational method through psychological and religious interpretation. This study is to challenge and encourage many han-ridden people in Korean society. Through the psychological and religious understanding of han, people suffering can positively transform their han. They can relate to han more subjectively, and this means the han-ridden psyche has an innate sacredness of potential to transform.

  18. Hybrid star structure with the Field Correlator Method

    Energy Technology Data Exchange (ETDEWEB)

    Burgio, G.F.; Zappala, D. [INFN, Catania (Italy)

    2016-03-15

    We explore the relevance of the color-flavor locking phase in the equation of state (EoS) built with the Field Correlator Method (FCM) for the description of the quark matter core of hybrid stars. For the hadronic phase, we use the microscopic Brueckner-Hartree-Fock (BHF) many-body theory, and its relativistic counterpart, i.e. the Dirac-Brueckner (DBHF). We find that the main features of the phase transition are directly related to the values of the quark-antiquark potential V{sub 1}, the gluon condensate G{sub 2} and the color-flavor superconducting gap Δ. We confirm that the mapping between the FCM and the CSS (constant speed of sound) parameterization holds true even in the case of paired quark matter. The inclusion of hyperons in the hadronic phase and its effect on the mass-radius relation of hybrid stars is also investigated. (orig.)

  19. Migration Correlation: Estimation Method and Application to French Corporates Ratings

    OpenAIRE

    Sandra FOULCHER; Gourieroux, Christian; Tiomo, André

    2006-01-01

    One major topic in empirical studies on Finance is the correlation of default risk. Correlation is a main driver for credit risk on a credit portfolio and for bank's capital requirement under the Basel II Accord. However, empirical evidence on the magnitude of correlation is rather scarce, mainly due to data limitation. First, the aim of this paper is to clarify the notion of correlation which depends on the underlying distributions and variables of interest. We suggest a general framework in...

  20. Applications of Digital Correlation Method to Structure Inspection

    Institute of Scientific and Technical Information of China (English)

    CHEN Junda; JIN Guanchang; MENG Libo

    2007-01-01

    In structure inspections, applications of optical techniques are rare, but the advantages of a noncontact, full field technique using a simple apparatus are attractive. The main requirements for structure inspection are the full-field strain measurement with the required precision and on-site measurement ability.The digital correlation method (DCM), a new optical deformation measurement tool, can satisfy all of the requirements for structure inspection. A smoothing algorithm which can greatly improve the strain measurement precision, and a 3-D DCM have been developed in this paper. For verifying this improvement, a comparison of strain measurements by computer-simulated speckle images has been carried out. Additionally,three structure inspection examples that cover typical materials and structure styles are presented: the interface shear stress distribution for reinforced concrete piles bedded on rock, the 3-D strain distribution of a composite vessel structure, and stresses in a hookup that connects two steel bridge structures. All the examples show that the new structural inspection tool is exemplary and illustrates the obvious advantages of this optical non-destructive technique.

  1. Generalized Method for Sampling Spatially Correlated Heterogeneous Speckled Imagery

    Directory of Open Access Journals (Sweden)

    Alejandro C. Frery

    2001-06-01

    Full Text Available This paper presents a general result for the simulation of correlated heterogeneous targets, which are present in images corrupted by speckle noise. This technique is based on the use of a correlation mask and Gaussian random variables, in order to obtain spatially dependent Gamma deviates. These Gamma random variables, in turn, allow the obtainment of correlated 𝒦 deviates with specified correlation structure. The theoretical properties of the procedure are presented, along with the corresponding algorithm.

  2. Advanced cluster methods for correlated-electron systems

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Andre

    2015-04-27

    In this thesis, quantum cluster methods are used to calculate electronic properties of correlated-electron systems. A special focus lies in the determination of the ground state properties of a 3/4 filled triangular lattice within the one-band Hubbard model. At this filling, the electronic density of states exhibits a so-called van Hove singularity and the Fermi surface becomes perfectly nested, causing an instability towards a variety of spin-density-wave (SDW) and superconducting states. While chiral d+id-wave superconductivity has been proposed as the ground state in the weak coupling limit, the situation towards strong interactions is unclear. Additionally, quantum cluster methods are used here to investigate the interplay of Coulomb interactions and symmetry-breaking mechanisms within the nematic phase of iron-pnictide superconductors. The transition from a tetragonal to an orthorhombic phase is accompanied by a significant change in electronic properties, while long-range magnetic order is not established yet. The driving force of this transition may not only be phonons but also magnetic or orbital fluctuations. The signatures of these scenarios are studied with quantum cluster methods to identify the most important effects. Here, cluster perturbation theory (CPT) and its variational extention, the variational cluster approach (VCA) are used to treat the respective systems on a level beyond mean-field theory. Short-range correlations are incorporated numerically exactly by exact diagonalization (ED). In the VCA, long-range interactions are included by variational optimization of a fictitious symmetry-breaking field based on a self-energy functional approach. Due to limitations of ED, cluster sizes are limited to a small number of degrees of freedom. For the 3/4 filled triangular lattice, the VCA is performed for different cluster symmetries. A strong symmetry dependence and finite-size effects make a comparison of the results from different clusters difficult

  3. Set Correlation as a General Multivariate Data-Analytic Method.

    Science.gov (United States)

    Cohen, Jacob

    1982-01-01

    Set correlation is a multivariate generalization of multiple regression/correlation analysis that features the employment of overall measures of association interpretable as proportions of variance and the use of set-partialled sets of variables. The statistical development of the theory and several examples are presented. (Author/JKS)

  4. Investigation of phase stability in the scandia-zirconia; Investigacao da estabilidade de fases da zirconia-escandia

    Energy Technology Data Exchange (ETDEWEB)

    Grosso, Robson Lopes

    2016-11-01

    In this work, the phase stability of scandia-zirconia (ScSZ) system was investigated by the thermodynamic study of nanoparticles, within the range of 0 to 20 mol% Sc{sub 2}O{sub 3}, and by codoping of ZrO{sub 2}-10 mol% Sc{sub 2}O{sub 3} (10ScSZ) with Dy{sub 2}O{sub 3} and Nb{sub 2}O{sub 5}. The phase stability of ScSZ was evaluated based on thermodynamic data collected by water adsorption microcalorimetry and high temperature oxide melt solution. Nanostructured zirconia-scandia solid solutions were synthesized by coprecipitation method. Thermodynamic data were determined for ScSZ polymorph (monoclinic, tetragonal, cubic, rhombohedral β and γ) found by X-ray diffraction. This systemic work resulted in an unprecedented phase diagram at the nanoscale of particle size-composition. The effects of additives on 10ScSZ were investigated aiming to stabilize the cubic (c) structure at room temperature and to suppress the characteristic cubic-rhombohedral β phase transformation. Compositions were prepared by coprecipitation and solid state reaction. Materials were sintered by conventional and spark plasma sintering. Full stabilization of the cubic phase was attained by 1 mol% Dy{sub 2}O{sub 3} and 0.5 mol% Nb{sub 2}O{sub 5} additions. The smallest Nb{sub 2}O{sub 5} content required for cubic phase stabilization was attributed to liquid phase formation during sintering and to small ionic radius of Nb{sup 5+}. Results of high temperature X-ray diffraction and thermal analysis show suppression of the c-β transformation. Samples containing 0.5 mol% Nb{sub 2}O{sub 5} show total ionic conductivity similar to 10ScSZ without additives within a broad temperature range with high stability during 170 h at 600 °C. (author)

  5. PHREATOPHYTE WATER USE ESTIMATED BY EDDY-CORRELATION METHODS.

    Science.gov (United States)

    Weaver, H.L.; Weeks, E.P.; Campbell, G.S.; Stannard, D.I.; Tanner, B.D.

    1986-01-01

    Water-use was estimated for three phreatophyte communities: a saltcedar community and an alkali-Sacaton grass community in New Mexico, and a greasewood rabbit-brush-saltgrass community in Colorado. These water-use estimates were calculated from eddy-correlation measurements using three different analyses, since the direct eddy-correlation measurements did not satisfy a surface energy balance. The analysis that seems to be most accurate indicated the saltcedar community used from 58 to 87 cm (23 to 34 in. ) of water each year. The other two communities used about two-thirds this quantity.

  6. Spectral methods and cluster structure in correlation-based networks

    Science.gov (United States)

    Heimo, Tapio; Tibély, Gergely; Saramäki, Jari; Kaski, Kimmo; Kertész, János

    2008-10-01

    We investigate how in complex systems the eigenpairs of the matrices derived from the correlations of multichannel observations reflect the cluster structure of the underlying networks. For this we use daily return data from the NYSE and focus specifically on the spectral properties of weight W=|-δ and diffusion matrices D=W/sj-δ, where C is the correlation matrix and si=∑jW the strength of node j. The eigenvalues (and corresponding eigenvectors) of the weight matrix are ranked in descending order. As in the earlier observations, the first eigenvector stands for a measure of the market correlations. Its components are, to first approximation, equal to the strengths of the nodes and there is a second order, roughly linear, correction. The high ranking eigenvectors, excluding the highest ranking one, are usually assigned to market sectors and industrial branches. Our study shows that both for weight and diffusion matrices the eigenpair analysis is not capable of easily deducing the cluster structure of the network without a priori knowledge. In addition we have studied the clustering of stocks using the asset graph approach with and without spectrum based noise filtering. It turns out that asset graphs are quite insensitive to noise and there is no sharp percolation transition as a function of the ratio of bonds included, thus no natural threshold value for that ratio seems to exist. We suggest that these observations can be of use for other correlation based networks as well.

  7. An edge-adaptive demosaicking method based on image correlation

    Institute of Scientific and Technical Information of China (English)

    贾晓芬; 赵佰亭; 周孟然; 陈兆权

    2015-01-01

    To reduce the cost, size and complexity, a consumer digital camera usually uses a single sensor overlaid with a color filter array (CFA) to sample one of the red−green−blue primary color values, and uses demosaicking algorithm to estimate the missing color values at each pixel. A novel image correlation and support vector machine (SVM) based edge-adaptive algorithm was proposed, which can reduce edge artifacts and false color artifacts, effectively. Firstly, image pixels were separated into edge region and smooth region with an edge detection algorithm. Then, a hybrid approach switching between a simple demosaicking algorithm on the smooth region and SVM based demosaicking algorithm on the edge region was performed. Image spatial and spectral correlations were employed to create middle planes for the interpolation. Experimental result shows that the proposed approach produced visually pleasing full-color result images and obtained higher CPSNR and smaller S-CIELAB *abDE than other conventional demosaicking algorithms.

  8. Correlation of the summary method with learning styles.

    Science.gov (United States)

    Sarikcioglu, Levent; Senol, Yesim; Yildirim, Fatos B; Hizay, Arzu

    2011-09-01

    The summary is the last part of the lesson but one of the most important. We aimed to study the relationship between the preference of the summary method (video demonstration, question-answer, or brief review of slides) and learning styles. A total of 131 students were included in the present study. An inventory was prepared to understand the students' learning styles, and a satisfaction questionnaire was provided to determine the summary method selection. The questionnaire and inventory were collected and analyzed. A comparison of the data revealed that the summary method with video demonstration received the highest score among all the methods tested. Additionally, there were no significant differences between learning styles and summary method with video demonstration. We suggest that such a summary method should be incorporated into neuroanatomy lessons. Since anatomy has a large amount of visual material, we think that it is ideally suited for this summary method.

  9. Ground State Correlations and the Multiconfiguration Mixing Method

    CERN Document Server

    Pillet, N; Van Giai, N; Berger, J F; Giai, Nguyen Van

    2004-01-01

    We study the convergence properties of a truncation scheme in describing the ground state properties of a many-particle system of fermions. The model wave function is built within a multiconfiguration mixing approach where the many-body wave function is described as a superposition of multiparticle-multihole configurations constructed upon a Slater determinant. The convergence properties of physical quantities such as correlation energies and single-particle occupation probabilities in terms of the increasing number of particle-hole configurations are investigated for the case of an exactly solvable pairing hamiltonian.

  10. The Numerical Renormalization Group Method for correlated electrons

    OpenAIRE

    Bulla, Ralf

    2000-01-01

    The Numerical Renormalization Group method (NRG) has been developed by Wilson in the 1970's to investigate the Kondo problem. The NRG allows the non-perturbative calculation of static and dynamic properties for a variety of impurity models. In addition, this method has been recently generalized to lattice models within the Dynamical Mean Field Theory. This paper gives a brief historical overview of the development of the NRG and discusses its application to the Hubbard model; in particular th...

  11. Correlates of the Rosenberg Self-Esteem Scale Method Effects

    Science.gov (United States)

    Quilty, Lena C.; Oakman, Jonathan M.; Risko, Evan

    2006-01-01

    Investigators of personality assessment are becoming aware that using positively and negatively worded items in questionnaires to prevent acquiescence may negatively impact construct validity. The Rosenberg Self-Esteem Scale (RSES) has demonstrated a bifactorial structure typically proposed to result from these method effects. Recent work suggests…

  12. Correlates of the Rosenberg Self-Esteem Scale Method Effects

    Science.gov (United States)

    Quilty, Lena C.; Oakman, Jonathan M.; Risko, Evan

    2006-01-01

    Investigators of personality assessment are becoming aware that using positively and negatively worded items in questionnaires to prevent acquiescence may negatively impact construct validity. The Rosenberg Self-Esteem Scale (RSES) has demonstrated a bifactorial structure typically proposed to result from these method effects. Recent work suggests…

  13. Investigation of the ROMP catalysis mechanism of norbornene using methods of density functional; Investigacao do mecanismo de catalise ROMP do norborneno utilizando metodos de funcional de densidade

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Carlos Pereira da, E-mail: carlosps1985@gmail.co [Institutor Federal de Educacao, Ciencia e Tecnologia do Piaui, Teresina, PI (Brazil); Lima, Francisco das Chagas Alves [Universidade Estadual do Piaui, Teresina, PI (Brazil). Coordenacao de Quimica; Leal, Regis Casimiro; Moita Neto, Jose Machado [Universidade Federal do Piaui (UFPI), Teresina, PI (Brazil)

    2010-07-01

    This work presents a density functional theory study of the norbornene ROMP metathesis reactions. The energies have been calculated in a Grubbs catalyst model Cl{sub 2}(PH{sub 3}){sub 2}Ru=CH{sub 2}. The geometries and energy profile are similar to the Grubbs methylidene (Cl{sub 2}(PCy{sub 3}){sub 2}Ru=CH{sub 2} real model. It was found that the metathesis reaction proceeds via associative mechanism (catalyst-norbornene) followed by dissociative substitution of a phosphine ligand with norbornene, giving a monophosphine complex. The results are in reasonable agreement with the available experimental data. The dissociation energy of the phosphines is predicted to be 23.2 kcal mol{sup -1}. (author)

  14. On the Brodutch and Modi method of constructing geometric measures of classical and quantum correlations

    Science.gov (United States)

    Walczak, Zbigniew; Wintrowicz, Iwona

    2017-03-01

    Recently, Brodutch and Modi proposed a general method of constructing meaningful measures of classical and quantum correlations. We systematically apply this method to obtain geometric classical and quantum correlations based on the Bures and the trace distances for two-qubit Bell diagonal states. Moreover, we argue that in general the Brodutch and Modi method may provide non-unique results, and we show how to modify this method to avoid this issue.

  15. A comparison of confidence interval methods for the concordance correlation coefficient and intraclass correlation coefficient with small number of raters.

    Science.gov (United States)

    Feng, Dai; Svetnik, Vladimir; Coimbra, Alexandre; Baumgartner, Richard

    2014-01-01

    The intraclass correlation coefficient (ICC) with fixed raters or, equivalently, the concordance correlation coefficient (CCC) for continuous outcomes is a widely accepted aggregate index of agreement in settings with small number of raters. Quantifying the precision of the CCC by constructing its confidence interval (CI) is important in early drug development applications, in particular in qualification of biomarker platforms. In recent years, there have been several new methods proposed for construction of CIs for the CCC, but their comprehensive comparison has not been attempted. The methods consisted of the delta method and jackknifing with and without Fisher's Z-transformation, respectively, and Bayesian methods with vague priors. In this study, we carried out a simulation study, with data simulated from multivariate normal as well as heavier tailed distribution (t-distribution with 5 degrees of freedom), to compare the state-of-the-art methods for assigning CI to the CCC. When the data are normally distributed, the jackknifing with Fisher's Z-transformation (JZ) tended to provide superior coverage and the difference between it and the closest competitor, the Bayesian method with the Jeffreys prior was in general minimal. For the nonnormal data, the jackknife methods, especially the JZ method, provided the coverage probabilities closest to the nominal in contrast to the others which yielded overly liberal coverage. Approaches based upon the delta method and Bayesian method with conjugate prior generally provided slightly narrower intervals and larger lower bounds than others, though this was offset by their poor coverage. Finally, we illustrated the utility of the CIs for the CCC in an example of a wake after sleep onset (WASO) biomarker, which is frequently used in clinical sleep studies of drugs for treatment of insomnia.

  16. A New Generation Method for Spatial-Temporal Correlated MIMO Nakagami Fading Channel

    Directory of Open Access Journals (Sweden)

    Qiu-Ming Zhu

    2012-01-01

    Full Text Available A new generation method for spatial and temporal correlated multiple-input multiple-output (MIMO Nakagami fading channel is proposed, which has low complexity and is applicable for arbitrary fading parameters and prespecified correlation coefficients of different subchannel. The new scheme can be divided into two steps: (1 generate independent Nakagami fading sequences for each subchannel based on a novel rejection method; (2 introduce the temporal and spatial correlation based on the relationships between Rayleigh, Gamma, and Nakagami random processes. The analysis and simulation results show that the proposed simulator has a good agreement with the theoretical model on fading envelope distribution, spatial-temporal correlation characteristic.

  17. A NEW SYSTEM DYNAMIC EXTREMUM SELF-SEARCHING METHOD BASED ON CORRELATION ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    李嘉; 刘文江; 胡军; 袁廷奇

    2003-01-01

    Objective To propose a new dynamic extremum self-searching method, which can be used in industrial processes extremum optimum control systems, to overcome the disadvantages of traditional method. Methods This algorithm is based on correlation analysis. A pseudo-random binary signal m-sequence u(t) is added as probe signal in system input, construct cross-correlation function between system input and output, the next step hunting direction is judged by the differential sign. Results Compared with traditional algorithm such as step forward hunting method, the iterative efficient, hunting precision and anti-interference ability of the correlation analysis method is obvious over the traditional algorithm. The computer simulation experimental given illustrate these viewpoints. Conclusion The correlation analysis method can settle the optimum state point of device operating process. It has the advantage of easy condition , simple calculate process.

  18. A correlation based fault detection method for short circuits in battery packs

    Science.gov (United States)

    Xia, Bing; Shang, Yunlong; Nguyen, Truong; Mi, Chris

    2017-01-01

    This paper presents a fault detection method for short circuits based on the correlation coefficient of voltage curves. The proposed method utilizes the direct voltage measurements from the battery cells, and does not require any additional hardware or effort in modeling during fault detection. Moreover, the inherent mathematical properties of the correlation coefficient ensure the robustness of this method as the battery pack ages or is imbalanced in real applications. In order to apply this method online, the recursive moving window correlation coefficient calculation is adopted to maintain the detection sensitivity to faults during operation. An additive square wave is designed to prevent false positive detections when the batteries are at rest. The fault isolation can be achieved by identifying the overlapped cell in the correlation coefficients with fault flags. Simulation and experimental results validated the feasibility and demonstrated the advantages of this method.

  19. Estimating genetic correlations based on phenotypic data: a simulation-based method

    Indian Academy of Sciences (India)

    Elias Zintzaras

    2011-04-01

    Knowledge of genetic correlations is essential to understand the joint evolution of traits through correlated responses to selection, a difficult and seldom, very precise task even with easy-to-breed species. Here, a simulation-based method to estimate genetic correlations and genetic covariances that relies only on phenotypic measurements is proposed. The method does not require any degree of relatedness in the sampled individuals. Extensive numerical results suggest that the propose method may provide relatively efficient estimates regardless of sample sizes and contributions from common environmental effects.

  20. Extension of the spatial autocorrelation (SPAC) method to mixed-component correlations of surface waves

    Science.gov (United States)

    Haney, Matthew M.; Mikesell, T. Dylan; van Wijk, Kasper; Nakahara, Hisashi

    2012-01-01

    Using ambient seismic noise for imaging subsurface structure dates back to the development of the spatial autocorrelation (SPAC) method in the 1950s. We present a theoretical analysis of the SPAC method for multicomponent recordings of surface waves to determine the complete 3 × 3 matrix of correlations between all pairs of three-component motions, called the correlation matrix. In the case of isotropic incidence, when either Rayleigh or Love waves arrive from all directions with equal power, the only non-zero off-diagonal terms in the matrix are the vertical–radial (ZR) and radial–vertical (RZ) correlations in the presence of Rayleigh waves. Such combinations were not considered in the development of the SPAC method. The method originally addressed the vertical–vertical (ZZ), RR and TT correlations, hence the name spatial autocorrelation. The theoretical expressions we derive for the ZR and RZ correlations offer additional ways to measure Rayleigh wave dispersion within the SPAC framework. Expanding on the results for isotropic incidence, we derive the complete correlation matrix in the case of generally anisotropic incidence. We show that the ZR and RZ correlations have advantageous properties in the presence of an out-of-plane directional wavefield compared to ZZ and RR correlations. We apply the results for mixed-component correlations to a data set from Akutan Volcano, Alaska and find consistent estimates of Rayleigh wave phase velocity from ZR compared to ZZ correlations. This work together with the recently discovered connections between the SPAC method and time-domain correlations of ambient noise provide further insights into the retrieval of surface wave Green’s functions from seismic noise.

  1. Cross-Correlation-Function-Based Multipath Mitigation Method for Sine-BOC Signals

    Directory of Open Access Journals (Sweden)

    H. H. Chen

    2012-06-01

    Full Text Available Global Navigation Satellite Systems (GNSS positioning accuracy indoor and urban canyons environments are greatly affected by multipath due to distortions in its autocorrelation function. In this paper, a cross-correlation function between the received sine phased Binary Offset Carrier (sine-BOC modulation signal and the local signal is studied firstly, and a new multipath mitigation method based on cross-correlation function for sine-BOC signal is proposed. This method is implemented to create a cross-correlation function by designing the modulated symbols of the local signal. The theoretical analysis and simulation results indicate that the proposed method exhibits better multipath mitigation performance compared with the traditional Double Delta Correlator (DDC techniques, especially the medium/long delay multipath signals, and it is also convenient and flexible to implement by using only one correlator, which is the case of low-cost mass-market receivers.

  2. Time domain averaging and correlation-based improved spectrum sensing method for cognitive radio

    Science.gov (United States)

    Li, Shenghong; Bi, Guoan

    2014-12-01

    Based on the combination of time domain averaging and correlation, we propose an effective time domain averaging and correlation-based spectrum sensing (TDA-C-SS) method used in very low signal-to-noise ratio (SNR) environments. With the assumption that the received signals from the primary users are deterministic, the proposed TDA-C-SS method processes the received samples by a time averaging operation to improve the SNR. Correlation operation is then performed with a correlation matrix to determine the existence of the primary signal in the received samples. The TDA-C-SS method does not need any prior information on the received samples and the associated noise power to achieve improved sensing performance. Simulation results are presented to show the effectiveness of the proposed TDA-C-SS method.

  3. A new method to determine the energy of vanishing flow, using particle-particle azimuthal correlations

    Energy Technology Data Exchange (ETDEWEB)

    Buta, A. [Caen Univ., 14 (France). Lab. de Physique Corpusculaire]|[Institute of Atomic Physics, Bucharest (Romania); Angelique, J.C.; Bizard, G.; Brou, R.; Cussol, D. [Caen Univ., 14 (France). Lab. de Physique Corpusculaire; Auger, G.; Cabot, C. [Grand Accelerateur National d`Ions Lourds (GANIL), 14 - Caen (France); Cassagnou, Y. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. d`Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l`Instrumentation Associee; Crema, E. [Caen Univ., 14 (France). Lab. de Physique Corpusculaire]|[Sao Paulo Univ., SP (Brazil). Inst. de Fisica; El Masri, Y. [Louvain Univ., Louvain-la-Neuve (Belgium). Unite de Physique Nucleaire; and others

    1996-09-01

    Measuring the in-plane flow parameter appears to be a promising method to gain information on the equation of state of nuclear matter. A new method, based on particle-particle azimuthal correlations is proposed. This method does not require the knowledge of the reaction plane. The collisions Zn+Ni and Ar+Al are presented as an example. (K.A.).

  4. A Simple Superresolution Approach of Multipath Delay Profiles Measured by PN Correlation Method

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Time resolution of multipath delay profiles measured by using autocorrelation of pseudonoise (PN) code sequence is generally limitec by the chip rate of the PN code sequence. In this paper, we propose a simple method to improve the time resolution of delay profiles measured by the PN correlation method. Effectiveness of this method is demonstrated by indoor wireless propagation experiments.

  5. Structural carbohydrates in a plant biomass: correlations between the detergent fiber and dietary fiber methods.

    Science.gov (United States)

    Godin, Bruno; Agneessens, Richard; Gerin, Patrick; Delcarte, Jérôme

    2014-06-18

    We compared the detergent fiber and dietary fiber methods to analyze the cellulose and hemicellulose contents of commelinid and non-commelinid magnoliophyta biomass. A good linear correlation was found between both methods. Compared to the more accurate dietary fiber method, the detergent fiber method overestimates the content of cellulose, whereas the detergent fiber method, as compared to the dietary fiber method, overestimates and underestimates the hemicellulose content in commelinid and non-commelinid magnoliophyta biomass, respectively. Because of the good linear correlations, conversion factors were determined to predict the cellulose, hemicellulose, and xylan contents to be expected from the dietary fiber method, on the basis of analyses made by the faster, cheaper, and more commonly practiced detergent fiber method. Nevertheless, the dietary fiber method offers the advantage of providing the detailed composition of the hemicelluloses (xylan, arabinan, hemicellulosic glucan, galactan, and mannan), and that is of interest for biorefining purposes.

  6. SPECTRAL CORRELATION METHOD IN THE IDENTIFICATION OF FREQUENCY-SELECTIVE FADING RADIO ENVIRONMENT

    Institute of Scientific and Technical Information of China (English)

    Weng Hong; Wang Hongyuan; Yu Guowen

    2006-01-01

    Many modulated communication signals exhibit a cyclostationarity (or periodic correlation) property. To exploit the underlying periodicity of the modulated signal in the real-time recognition scheme of radio environments, this letter introduces a spectral correlation method to identify the number and the direction of multi-path in the environment of frequency-selective fading channel. By simulation, the graphs of spatial spectra corresponding to a certain cycle frequency is presented to show the accuracy of spectral correlation method in multi-path environment recognition.

  7. A combined method for correlative 3D imaging of biological samples from macro to nano scale

    Science.gov (United States)

    Kellner, Manuela; Heidrich, Marko; Lorbeer, Raoul-Amadeus; Antonopoulos, Georgios C.; Knudsen, Lars; Wrede, Christoph; Izykowski, Nicole; Grothausmann, Roman; Jonigk, Danny; Ochs, Matthias; Ripken, Tammo; Kühnel, Mark P.; Meyer, Heiko

    2016-10-01

    Correlative analysis requires examination of a specimen from macro to nano scale as well as applicability of analytical methods ranging from morphological to molecular. Accomplishing this with one and the same sample is laborious at best, due to deformation and biodegradation during measurements or intermediary preparation steps. Furthermore, data alignment using differing imaging techniques turns out to be a complex task, which considerably complicates the interconnection of results. We present correlative imaging of the accessory rat lung lobe by combining a modified Scanning Laser Optical Tomography (SLOT) setup with a specially developed sample preparation method (CRISTAL). CRISTAL is a resin-based embedding method that optically clears the specimen while allowing sectioning and preventing degradation. We applied and correlated SLOT with Multi Photon Microscopy, histological and immunofluorescence analysis as well as Transmission Electron Microscopy, all in the same sample. Thus, combining CRISTAL with SLOT enables the correlative utilization of a vast variety of imaging techniques.

  8. A new method to estimate the noise in financial correlation matrices

    Energy Technology Data Exchange (ETDEWEB)

    Guhr, Thomas [Matematisk Fysik, LTH, Lunds Universitet, Box 118, 22100 Lund (Sweden); Kaelber, Bernd [Max Planck Institut fuer Kernphysik, Postfach 103980, 69029 Heidelberg (Germany)

    2003-03-28

    Companies belonging to the same industrial branch are subject to similar economical influences. Hence, the time series of their stocks can show similar trends implying a correlation. Financial correlation matrices measure the unsystematic correlations between time series of stocks. Such information is important for risk management. It has been found by Laloux et al that the correlation matrices are 'noise dressed', a major reason being the finiteness of the time series. We present a new and alternative method to estimate this noise. We introduce a power mapping of the elements in the correlation matrix which suppresses the noise and thereby effectively 'prolongs' the time series. Neither further data processing nor additional input is needed. To develop and test our method, we use a model suggested by Noh which can be viewed as a special case of a 'factor model' in economics. We perform numerical simulations for the time series and obtain correlation matrices. We support the numerics by a qualitative analytical discussion. With our approach, different correlation structures buried under this noise can be detected. Our method is general and can be applied to all systems in which time series are measured.

  9. A new method to estimate the noise in financial correlation matrices

    Science.gov (United States)

    Guhr, Thomas; Kälber, Bernd

    2003-03-01

    Companies belonging to the same industrial branch are subject to similar economical influences. Hence, the time series of their stocks can show similar trends implying a correlation. Financial correlation matrices measure the unsystematic correlations between time series of stocks. Such information is important for risk management. It has been found by Laloux et al that the correlation matrices are 'noise dressed', a major reason being the finiteness of the time series. We present a new and alternative method to estimate this noise. We introduce a power mapping of the elements in the correlation matrix which suppresses the noise and thereby effectively 'prolongs' the time series. Neither further data processing nor additional input is needed. To develop and test our method, we use a model suggested by Noh which can be viewed as a special case of a 'factor model' in economics. We perform numerical simulations for the time series and obtain correlation matrices. We support the numerics by a qualitative analytical discussion. With our approach, different correlation structures buried under this noise can be detected. Our method is general and can be applied to all systems in which time series are measured.

  10. Probabilistic power flow using improved Monte Carlo simulation method with correlated wind sources

    Science.gov (United States)

    Bie, Pei; Zhang, Buhan; Li, Hang; Deng, Weisi; Wu, Jiasi

    2017-01-01

    Probabilistic Power Flow (PPF) is a very useful tool for power system steady-state analysis. However, the correlation among different random injection power (like wind power) brings great difficulties to calculate PPF. Monte Carlo simulation (MCS) and analytical methods are two commonly used methods to solve PPF. MCS has high accuracy but is very time consuming. Analytical method like cumulants method (CM) has high computing efficiency but the cumulants calculating is not convenient when wind power output does not obey any typical distribution, especially when correlated wind sources are considered. In this paper, an Improved Monte Carlo simulation method (IMCS) is proposed. The joint empirical distribution is applied to model different wind power output. This method combines the advantages of both MCS and analytical method. It not only has high computing efficiency, but also can provide solutions with enough accuracy, which is very suitable for on-line analysis.

  11. Study on Correlation and Quantitative Error Estimation Method Among the Splitting Shear Wave Identification Methods

    Institute of Scientific and Technical Information of China (English)

    Liu Xiqiang; Zhou Huilan; Li Hong; Gai Dianguang

    2000-01-01

    Based on the propagation characteristics of shear wave in the anisotropic layers, thecorrelation among several splitting shear-wave identification methods hasbeen studied. Thispaper puts forward the method estimating splitting shear-wave phases and its reliability byusing of the assumption that variance of noise and useful signal data obey normaldistribution. To check the validity of new method, the identification results and errorestimation corresponding to 95% confidence level by analyzing simulation signals have beengiven.

  12. AN IMPROVED CROSS-CORRELATION METHOD FOR (DIGITAL) PARTICLE IMAGE VELOCIMETRY

    Institute of Scientific and Technical Information of China (English)

    翁文国; 范维澄; 廖光煊; 秦俊

    2001-01-01

    An improved method that brings enhancement in accuracy for the interrogation of (digital) PIV images is described in this paper. This method is based on cross-correlation with discrete window offset, which makes use of a translation of the second interrogation window and rebuilds it considering rotation and shear.The displacement extracted from PIV images is predicted and corrected by means of an iterative procedure. In addition, the displacement vectors are validated at each intermediate of the iteration process. The present improved cross-correlation method is compared with the conventional one in accuracy by interrogation of synthetic and real (digital) PIV images and the interrogation results are discussed.

  13. Correlation-interferometr method of DF with dispersion transformationof complex cross spectrum of signals.

    Directory of Open Access Journals (Sweden)

    V. V. Tsyporenko

    2010-05-01

    Full Text Available Tо digital method of dispersion cross-correlation DF which differs of subsequent direct determination of delay and proper direction to the source of radio radiation is developed. The compare analyze of fast-acting and error of developed method is executed.

  14. Variational multiparticle-multihole configuration mixing method applied to pairing correlations in nuclei

    CERN Document Server

    Pillet, N; Caurier, E

    2008-01-01

    Applying a variational multiparticle-multihole configuration mixing method whose purpose is to include correlations beyond the mean field in a unified way without particle number and Pauli principle violations, we investigate pairing-like correlations in the ground states of $ ^{116}$Sn,$ ^{106}$Sn and $ ^{100}$Sn. The same effective nucleon-nucleon interaction namely, the D1S parameterization of the Gogny force is used to derive both the mean field and correlation components of nuclear wave functions. Calculations are performed using an axially symetric representation. The structure of correlated wave functions, their convergence with respect to the number of particle-hole excitations and the influence of correlations on single-particle level spectra and occupation probabilities are analyzed and compared with results obtained with the same two-body effective interaction from BCS, Hartree-Fock-Bogoliubov and particle number projected after variation BCS approaches. Calculations of nuclear radii and the first ...

  15. Spectral and network methods in the analysis of correlation matrices of stock returns

    CERN Document Server

    Heimo, T; Onnela, J P; Saramäki, J; Heimo, Tapio; Kaski, Kimmo; Onnela, Jukka-Pekka; Saramaki, Jari

    2007-01-01

    Correlation matrices inferred from stock return time series contain information on the behaviour of the market, especially on clusters of highly correlating stocks. Here we study a subset of New York Stock Exchange (NYSE) traded stocks and compare three different methods of analysis: i) spectral analysis, i.e. investigation of the eigenvalue-eigenvector pairs of the correlation matrix, ii) asset trees, obtained by constructing the maximal spanning tree of the correlation matrix, and iii) asset graphs, which are networks in which the strongest correlations are depicted as edges. We illustrate and discuss the localisation of the most significant modes of fluctuation, i.e. eigenvectors corresponding to the largest eigenvalues, on the asset trees and graphs.

  16. Information and treatment of unknown correlations in the combination of measurements using the BLUE method

    CERN Document Server

    Valassi, A

    2014-01-01

    We discuss the effect of large positive correlations in the combinations of several measurements of a single physical quantity using the Best Linear Unbiased Estimate (BLUE) method. We suggest a new approach for comparing the relative weights of the different measurements in their contributions to the combined knowledge about the unknown parameter, using the well-established concept of Fisher information. We argue, in particular, that one contribution to information comes from the collective interplay of the measurements through their correlations and that this contribution cannot be attributed to any of the individual measurements alone. We show that negative coefficients in the BLUE weighted average invariably indicate the presence of a regime of high correlations, where the effect of further increasing some of these correlations is that of reducing the error on the combined estimate. In these regimes, we stress that the correlations provided as input to BLUE combinations need to be assessed with extreme ca...

  17. Shale characteristics impact on Nuclear Magnetic Resonance (NMR fluid typing methods and correlations

    Directory of Open Access Journals (Sweden)

    Mohamed Mehana

    2016-06-01

    Full Text Available The development of shale reservoirs has brought a paradigm shift in the worldwide energy equation. This entails developing robust techniques to properly evaluate and unlock the potential of those reservoirs. The application of Nuclear Magnetic Resonance techniques in fluid typing and properties estimation is well-developed in conventional reservoirs. However, Shale reservoirs characteristics like pore size, organic matter, clay content, wettability, adsorption, and mineralogy would limit the applicability of the used interpretation methods and correlation. Some of these limitations include the inapplicability of the controlling equations that were derived assuming fast relaxation regime, the overlap of different fluids peaks and the lack of robust correlation to estimate fluid properties in shale. This study presents a state-of-the-art review of the main contributions presented on fluid typing methods and correlations in both experimental and theoretical side. The study involves Dual Tw, Dual Te, and doping agent's application, T1-T2, D-T2 and T2sec vs. T1/T2 methods. In addition, fluid properties estimation such as density, viscosity and the gas-oil ratio is discussed. This study investigates the applicability of these methods along with a study of the current fluid properties correlations and their limitations. Moreover, it recommends the appropriate method and correlation which are capable of tackling shale heterogeneity.

  18. How to combine correlated data sets-A Bayesian hyperparameter matrix method

    Science.gov (United States)

    Ma, Y.-Z.; Berndsen, A.

    2014-07-01

    We construct a “hyperparameter matrix” statistical method for performing the joint analyses of multiple correlated astronomical data sets, in which the weights of data sets are determined by their own statistical properties. This method is a generalization of the hyperparameter method constructed by Lahav et al. (2000) and Hobson et al. (2002) which was designed to combine independent data sets. The advantage of our method is to treat correlations between multiple data sets and gives appropriate relevant weights of multiple data sets with mutual correlations. We define a new “element-wise” product, which greatly simplifies the likelihood function with hyperparameter matrix. We rigorously prove the simplified formula of the joint likelihood and show that it recovers the original hyperparameter method in the limit of no covariance between data sets. We then illustrate the method by applying it to a demonstrative toy model of fitting a straight line to two sets of data. We show that the hyperparameter matrix method can detect unaccounted systematic errors or underestimated errors in the data sets. Additionally, the ratio of Bayes' factors provides a distinct indicator of the necessity of including hyperparameters. Our example shows that the likelihood we construct for joint analyses of correlated data sets can be widely applied to many astrophysical systems.

  19. Comparison of explicitly correlated local coupled-cluster methods with various choices of virtual orbitals.

    Science.gov (United States)

    Krause, Christine; Werner, Hans-Joachim

    2012-06-07

    Explicitly correlated local coupled-cluster (LCCSD-F12) methods with pair natural orbitals (PNOs), orbital specific virtual orbitals (OSVs), and projected atomic orbitals (PAOs) are compared. In all cases pair-specific virtual subspaces (domains) are used, and the convergence of the correlation energy as a function of the domain sizes is studied. Furthermore, the performance of the methods for reaction energies of 52 reactions involving 58 small and medium sized molecules is investigated. It is demonstrated that for all choices of virtual orbitals much smaller domains are needed in the explicitly correlated methods than without the explicitly correlated terms, since the latter correct a large part of the domain error, as found previously. For PNO-LCCSD-F12 with VTZ-F12 basis sets on the average only 20 PNOs per pair are needed to obtain reaction energies with a root mean square deviation of less than 1 kJ mol(-1) from complete basis set estimates. With OSVs or PAOs at least 4 times larger domains are needed for the same accuracy. A new hybrid method that combines the advantages of the OSV and PNO methods is proposed and tested. While in the current work the different local methods are only simulated using a conventional CCSD program, the implications for low-order scaling local implementations of the various methods are discussed.

  20. How to combine correlated data sets -- A Bayesian hyperparameter matrix method

    CERN Document Server

    Ma, Yin-Zhe

    2013-01-01

    We construct a statistical method for performing the joint analyses of multiple correlated astronomical data sets, in which the weights of data sets are determined by their own statistical properties. This method is a generalization of the hyperparameter method constructed by \\cite{Lahav00} and \\cite{Hobson02} which was designed to combine independent data sets. The hyperparameter matrix method we present here includes the relevant weights of multiple data sets and mutual correlations, and when the hyperparameters are marginalized over, the parameters of interest are recovered. We define a new "element-wise" product, which greatly simplifies the likelihood function with hyperparameter matrix. We rigorously prove the simplified formula of the joint likelihood and show that it recovers the original hyperparameter method in the limit of no covariance between data sets. We then illustrate the method by applying a classic model of fitting a straight line to two sets of data. We show that the hyperparameter matrix ...

  1. Verification of Engineering-Geological/Geotechnical Correlation Column and Reference Level of Correlation (RNK) Method by Observations in the Slip-Plane Zone

    OpenAIRE

    Jurak, V.; Ortolan, Ž.; Slovenec, D.; Mihalinec, Z.

    2004-01-01

    The engineering-geological/geotechnical correlation column can be established in zones of limited extent using one or several characteristic layers, one of which is selected as the reference layer. The Reference Level of Correlation method, i.e. the RNK (Referentni nivo korelacije in Croatian) method, is a confirmed procedure enabling the establishment of such columns. In the engineering geological/geotechnical correlation column, the plasticity index is the most significant indicator of the ...

  2. Linear methods for input scenes restoration from signals of optical-digital pattern recognition correlator

    Science.gov (United States)

    Starikov, Sergey N.; Konnik, Mikhail V.; Manykin, Edward A.; Rodin, Vladislav G.

    2009-04-01

    Linear methods of restoration of input scene's images in optical-digital correlators are described. Relatively low signal to noise ratio of a camera's photo sensor and extensional PSF's size are special features of considered optical-digital correlator. RAW-files of real correlation signals obtained by digital photo sensor were used for input scene's images restoration. It is shown that modified evolution method, which employs regularization by Tikhonov, is better among linear deconvolution methods. As a regularization term, an inverse signal to noise ratio as a function of spatial frequencies was used. For additional improvement of restoration's quality, noise analysis of boundary areas of the image to be reconstructed was performed. Experimental results on digital restoration of input scene's images are presented.

  3. The feasibility and application of gray scale adjustment method in high temperature digital image correlation

    Science.gov (United States)

    Wang, Shen; Yao, Xue Feng; Su, Yun Quan; Liu, Wei

    2017-02-01

    In this paper, the basic principle and application of linear gray scale adjustment method are investigated in high temperature digital image correlation (DIC) technology. First, the simple linear gray scale adjustment method is proposed, which can adjust the gray scale value of the saturated pixels and diminish the correlation error caused by the saturated pixels. Then, both the simulated high temperature images and DIC correlation results before and after the gray scale adjustment are provided and analyzed to verify its effectiveness, in which the displacement error decreased from 0.1 pixels to 0.04 pixels after the linear gray scale adjustment for high temperature images. Finally, the linear gray scale adjustment method is used to extract the displacement with high accuracy in high temperature experiment of SiC specimen, and the displacement error decreased from 0.5 pixels to 0.1 pixels after the linear gray scale adjustment.

  4. A divergence-free method to extract observables from correlation functions

    Directory of Open Access Journals (Sweden)

    Si-xue Qin

    2015-03-01

    Full Text Available Correlation functions provide information on the properties of mesons in vacuum and of hot nuclear matter. In this work, we present a new method to derive a well-defined spectral representation for correlation functions. Combining this method with the quark gap equation and the inhomogeneous Bethe–Salpeter equation in the rainbow-ladder approximation, we calculate in-vacuum masses of light mesons and the electrical conductivity of the quark–gluon plasma. The analysis can be extended to other observables of strong-interaction systems.

  5. High Resolution Pulse Compression Imaging Using Super Resolution FM-Chirp Correlation Method (SCM)

    Science.gov (United States)

    Fujiwara, M.; Okubo, K.; Tagawa, N.

    This study addresses the issue of the super-resolution pulse compression technique (PCT) for ultrasound imaging. Time resolution of multiple ultrasonic echoes using the FM-Chirp PCT is limited by the bandwidth of the sweep-frequency. That is, the resolution depends on the sharpness of auto-correlation function. We propose the Super resolution FM-Chirp correlation Method (SCM) and evaluate its performance. This method is based on the multiple signal classification (MUSIC) algorithm. Our simulations were made for the model assuming multiple signals reflected from some scatterers. We confirmed that SCM detects time delay of complicated reflected signals successfully with high resolution.

  6. Correlation methods of base-level cycle based on wavelet neural network

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The authors discussed the method of wavelet neural network (WNN) for correlation of base-level cycle. A new vectored method of well log data was proposed. Through the training with the known data set, the WNN can remenber the cycle pattern characteristic of the well log curves. By the trained WNN to identify the cycle pattern in the vectored log data, the ocrrelation process among the well cycles was completed. The application indicates that it is highly efficient and reliable in base-level cycle correlation.

  7. A New Wavelet Threshold Determination Method Considering Interscale Correlation in Signal Denoising

    Directory of Open Access Journals (Sweden)

    Can He

    2015-01-01

    Full Text Available Due to simple calculation and good denoising effect, wavelet threshold denoising method has been widely used in signal denoising. In this method, the threshold is an important parameter that affects the denoising effect. In order to improve the denoising effect of the existing methods, a new threshold considering interscale correlation is presented. Firstly, a new correlation index is proposed based on the propagation characteristics of the wavelet coefficients. Then, a threshold determination strategy is obtained using the new index. At the end of the paper, a simulation experiment is given to verify the effectiveness of the proposed method. In the experiment, four benchmark signals are used as test signals. Simulation results show that the proposed method can achieve a good denoising effect under various signal types, noise intensities, and thresholding functions.

  8. Method for measuring radial impurity emission profiles using correlations of line integrated signals

    Science.gov (United States)

    Kuldkepp, M.; Brunsell, P. R.; Drake, J.; Menmuir, S.; Rachlew, E.

    2006-04-01

    A method of determining radial impurity emission profiles is outlined. The method uses correlations between line integrated signals and is based on the assumption of cylindrically symmetric fluctuations. Measurements at the reversed field pinch EXTRAP T2R show that emission from impurities expected to be close to the edge is clearly different in raw as well as analyzed data to impurities expected to be more central. Best fitting of experimental data to simulated correlation coefficients yields emission profiles that are remarkably close to emission profiles determined using more conventional techniques. The radial extension of the fluctuations is small enough for the method to be used and bandpass filtered signals indicate that fluctuations below 10kHz are cylindrically symmetric. The novel method is not sensitive to vessel window attenuation or wall reflections and can therefore complement the standard methods in the impurity emission reconstruction procedure.

  9. Fungible Correlation Matrices: A Method for Generating Nonsingular, Singular, and Improper Correlation Matrices for Monte Carlo Research.

    Science.gov (United States)

    Waller, Niels G

    2016-01-01

    For a fixed set of standardized regression coefficients and a fixed coefficient of determination (R-squared), an infinite number of predictor correlation matrices will satisfy the implied quadratic form. I call such matrices fungible correlation matrices. In this article, I describe an algorithm for generating positive definite (PD), positive semidefinite (PSD), or indefinite (ID) fungible correlation matrices that have a random or fixed smallest eigenvalue. The underlying equations of this algorithm are reviewed from both algebraic and geometric perspectives. Two simulation studies illustrate that fungible correlation matrices can be profitably used in Monte Carlo research. The first study uses PD fungible correlation matrices to compare penalized regression algorithms. The second study uses ID fungible correlation matrices to compare matrix-smoothing algorithms. R code for generating fungible correlation matrices is presented in the supplemental materials.

  10. Correlation imaging method based on local wavenumber for interpreting magnetic data

    Science.gov (United States)

    Ma, Guoqing; Liu, Cai; Xu, Jiashu; Meng, Qingfa

    2017-03-01

    Depth estimation is a general task in the interpretation of magnetic data, and local wavenumber is an effective tool to accomplish this task, but this method requires the structural index of causative source when applies it to compute the depth of the source, which is hard to obtain for an unknown area. In this paper, we suggested a correlation imaging method to interpret magnetic data, which uses the correlation coefficient of local wavenumber of real magnetic data and transformative local wavenumber of synthetic magnetic data generated by assumed source to estimate the location of the source, and this method does not require any priori information of the source and does not require solving any matrix. The computation steps as follows, first, we assume that the causative sources are distributed regularly as a rectangular grid, and then separately compute the correlation coefficient of the local wavenumber of real data and local wavenumber of the anomaly generated by each assumed source, and the correlation coefficient gets maximum when the location parameters of the assumed source are in accord with the true locations of real sources. The synthetic tested results show that this method can obtain the location of magnetic source effectively and correctly, and is insensitive to magnetization direction and noise. This method is also applied to measured magnetic data, and get the location parameters of the source.

  11. A spectral synthesis method to suppress aliasing and calibrate for delay errors in Fourier transform correlators

    CERN Document Server

    Kaneko, Tak

    2008-01-01

    Context: Fourier transform (or lag) correlators in radio interferometers can serve as an efficient means of synthesising spectral channels. However aliasing corrupts the edge channels so they usually have to be excluded from the data set. In systems with around 10 channels, the loss in sensitivity can be significant. In addition, the low level of residual aliasing in the remaining channels may cause systematic errors. Moreover, delay errors have been widely reported in implementations of broadband analogue correlators and simulations have shown that delay errors exasperate the effects of aliasing. Aims: We describe a software-based approach that suppresses aliasing by oversampling the cross-correlation function. This method can be applied to interferometers with individually-tracking antennas equipped with a discrete path compensator system. It is based on the well-known property of interferometers where the drift scan response is the Fourier transform of the source's band-limited spectrum. Methods: In this p...

  12. Method for vessel attitude estimation by spatial correlation function for bottom reverberation

    Institute of Scientific and Technical Information of China (English)

    FENG Lei; DENG Kai; WANG Changhong

    2006-01-01

    Under the assumption that the sea bottom is an almost-flat and randomly rough thin layer, a spatial correlation model for bottom reverberation is constructed. At high signal noise ratio, the phase of the spatial correlation function is the product of sound wave number and the vertical vector between two hydrophones. In a nominally horizontal plane, roll and pitch bring on the vertical vector between the hydrophones. Then an equation including roll, pitch and the phase of the spatial correlation function is found. If a parallelogram can be constructed by 3 hydrophones and the ratios of its acreage to diagonals are not smaller than half of the wavelength, roll and pitch can be obtained analytically or by optimal method. However, the ranges of roll and pitch are restricted because of the phase ambiguity. Using Fisher information matrix, the Cramer-Rao lower bound is obtained. Results from computer simulation and sea test data prove the feasibility of the method.

  13. Subpixel Accuracy Analysis of Phase Correlation Shift Measurement Methods Applied to Satellite Imagery

    Directory of Open Access Journals (Sweden)

    S.M. Badwai

    2013-01-01

    Full Text Available the key point of super resolution process is the accurate measuring of sub-pixel shift. Any tiny error in measuring such shift leads to an incorrect image focusing. In this paper, methodology of measuring sub-pixel shift using Phase correlation (PC are evaluated using different window functions, then modified version of (PC method using high pass filter (HPF is introduced . Comprehensive analysis and assessment of (PC methods shows that different natural features yield different shift measurements. It is concluded that there is no universal window function for measuring shift; it mainly depends on the features in the satellite images. Even the question of which window is optimal of particular feature is generally remains open. This paper presents the design of a method for obtaining high accuracy sub pixel shift phase correlation using (HPF.The proposed method makes the change in the different locations that lack of edges easy.

  14. Research of aluminium alloy aerospace structure aperture measurement based on 3D digital speckle correlation method

    Science.gov (United States)

    Bai, Lu; Wang, Hongbo; Zhou, Jiangfan; Yang, Rong; Zhang, Hui

    2014-11-01

    In this paper, the aperture change of the aluminium alloy aerospace structure under real load is researched. Static experiments are carried on which is simulated the load environment of flight course. Compared with the traditional methods, through experiments results, it's proved that 3D digital speckle correlation method has good adaptability and precision on testing aperture change, and it can satisfy measurement on non-contact,real-time 3D deformation or stress concentration. The test results of new method is compared with the traditional method.

  15. Isothermal thermogravimetric analysis of soybean oil oxidation correlated to thin film micro-oxidation test methods

    Science.gov (United States)

    A method of correlation between the Thin Film Micro-Oxidation (TFMO) test with isothermal thermogravimetric analysis is reported utilizing a soybean oil system. Utilizing a kinetic model, pseudo-rate constants and “activation energy” can be calculated from weight loss data. This model accounts for o...

  16. System reliability with correlated components: Accuracy of the Equivalent Planes method

    NARCIS (Netherlands)

    Roscoe, K.; Diermanse, F.; Vrouwenvelder, A.C.W.M.

    2015-01-01

    Computing system reliability when system components are correlated presents a challenge because it usually requires solving multi-fold integrals numerically, which is generally infeasible due to the computational cost. In Dutch flood defense reliability modeling, an efficient method for computing th

  17. Experimental investigation of interface curing stresses between PMMA and composite using digital speckle correlation method

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    This paper studies the interface curing stresses between polymethyl methacrylate (PMMA) and composite by means of digital speckle correlation method (DSCM).A new method by combining DSCM with the marker points is developed to measure the interface curing stresses,and the measurement principle is introduced.The interface curing stresses between PMMA and composite with different curing bonding conditions are measured and analyzed,this indicates that the residual stress for furnace heating and furnace cooling ...

  18. The use of photon correlation spectroscopy method for determining diffusion coefficient in brine and herring flesh

    Directory of Open Access Journals (Sweden)

    Shumanova M.V.

    2015-03-01

    Full Text Available The process fish salting has been studied by the method of photon correlation spectroscopy; the distribution of salt concentration in the solution and herring flesh with skin has been found, diffusion coefficients and salt concentrations used for creating a mathematical model of the salting technology have been worked out; the possibility of determination by this method the coefficient of dynamic viscosity of solutions and different media (minced meat etc. has been considered

  19. Clinical correlative evaluation of an iterative method for reconstruction of brain SPECT images

    Energy Technology Data Exchange (ETDEWEB)

    Nobili, Flavio E-mail: fnobili@smartino.ge.it; Vitali, Paolo; Calvini, Piero; Bollati, Francesca; Girtler, Nicola; Delmonte, Marta; Mariani, Giuliano; Rodriguez, Guido

    2001-08-01

    Background: Brain SPECT and PET investigations have showed discrepancies in Alzheimer's disease (AD) when considering data deriving from deeply located structures, such as the mesial temporal lobe. These discrepancies could be due to a variety of factors, including substantial differences in gamma-cameras and underlying technology. Mesial temporal structures are deeply located within the brain and the commonly used Filtered Back-Projection (FBP) technique does not fully take into account either the physical parameters of gamma-cameras or geometry of collimators. In order to overcome these limitations, alternative reconstruction methods have been proposed, such as the iterative method of the Conjugate Gradients with modified matrix (CG). However, the clinical applications of these methods have so far been only anecdotal. The present study was planned to compare perfusional SPECT data as derived from the conventional FBP method and from the iterative CG method, which takes into account the geometrical and physical characteristics of the gamma-camera, by a correlative approach with neuropsychology. Methods: Correlations were compared between perfusion of the hippocampal region, as achieved by both the FBP and the CG reconstruction methods, and a short-memory test (Selective Reminding Test, SRT), specifically addressing one of its function. A brain-dedicated camera (CERASPECT) was used for SPECT studies with {sup 99m}Tc-hexamethylpropylene-amine-oxime in 23 consecutive patients (mean age: 74.2{+-}6.5) with mild (Mini-Mental Status Examination score {>=}15, mean 20.3{+-}3), probable AD. Counts from a hippocampal region in each hemisphere were referred to the average thalamic counts. Results: Hippocampal perfusion significantly correlated with the MMSE score with similar statistical significance (p<0.01) between the two reconstruction methods. Correlation between hippocampal perfusion and the SRT score was better with the CG method (r=0.50 for both hemispheres, p<0

  20. How to use linear regression and correlation in quantitative method comparison studies.

    Science.gov (United States)

    Twomey, P J; Kroll, M H

    2008-04-01

    Linear regression methods try to determine the best linear relationship between data points while correlation coefficients assess the association (as opposed to agreement) between the two methods. Linear regression and correlation play an important part in the interpretation of quantitative method comparison studies. Their major strength is that they are widely known and as a result both are employed in the vast majority of method comparison studies. While previously performed by hand, the availability of statistical packages means that regression analysis is usually performed by software packages including MS Excel, with or without the software programe Analyze-it as well as by other software packages. Such techniques need to be employed in a way that compares the agreement between the two methods examined and more importantly, because we are dealing with individual patients, whether the degree of agreement is clinically acceptable. Despite their use for many years, there is a lot of ignorance about the validity as well as the pros and cons of linear regression and correlation techniques. This review article describes the types of linear regression and regression (parametric and non-parametric methods) and the necessary general and specific requirements. The selection of the type of regression depends on where one has been trained, the tradition of the laboratory and the availability of adequate software.

  1. Linear Confirmatory Factor Models To Evaluate Multitrait-Multimethod Matrices: The Effects of Number of Indicators and Correlation among Methods.

    Science.gov (United States)

    Tomas, Jose M.; Hontangas, Pedro M.; Oliver, Amparo

    2000-01-01

    Assessed two models for confirmatory factor analysis of multitrait-multimethod data through Monte Carlo simulation. The correlated traits-correlated methods (CTCM) and the correlated traits-correlated uniqueness (CTCU) models were compared. Results suggest that CTCU is a good alternative to CTCM in the typical multitrait-multimethod matrix, but…

  2. Data-driven fault detection for industrial processes canonical correlation analysis and projection based methods

    CERN Document Server

    Chen, Zhiwen

    2017-01-01

    Zhiwen Chen aims to develop advanced fault detection (FD) methods for the monitoring of industrial processes. With the ever increasing demands on reliability and safety in industrial processes, fault detection has become an important issue. Although the model-based fault detection theory has been well studied in the past decades, its applications are limited to large-scale industrial processes because it is difficult to build accurate models. Furthermore, motivated by the limitations of existing data-driven FD methods, novel canonical correlation analysis (CCA) and projection-based methods are proposed from the perspectives of process input and output data, less engineering effort and wide application scope. For performance evaluation of FD methods, a new index is also developed. Contents A New Index for Performance Evaluation of FD Methods CCA-based FD Method for the Monitoring of Stationary Processes Projection-based FD Method for the Monitoring of Dynamic Processes Benchmark Study and Real-Time Implementat...

  3. Spectral density analysis of time correlation functions in lattice QCD using the maximum entropy method

    CERN Document Server

    Fiebig, H R

    2002-01-01

    We study various aspects of extracting spectral information from time correlation functions of lattice QCD by means of Bayesian inference with an entropic prior, the maximum entropy method (MEM). Correlator functions of a heavy-light meson-meson system serve as a repository for lattice data with diverse statistical quality. Attention is given to spectral mass density functions, inferred from the data, and their dependence on the parameters of the MEM. We propose to employ simulated annealing, or cooling, to solve the Bayesian inference problem, and discuss practical issues of the approach.

  4. Electric vehicle chassis dynamometer test methods at JPL and their correlation to track tests

    Science.gov (United States)

    Marte, J.; Bryant, J.

    1983-01-01

    Early in its electric vehicle (EV) test program, JPL recognized that EV test procedures were too vague and too loosely defined to permit much meaningful data to be obtained from the testing. Therefore, JPL adopted more stringent test procedures and chose the chassis dynamometer rather than the track as its principal test technique. Through the years, test procedures continued to evolve towards a methodology based on chassis dynamometers which would exhibit good correlation with track testing. Based on comparative dynamometer and track test results on the ETV-1 vehicle, the test methods discussed in this report demonstrate a means by which excellent track-to-dynamometer correlation can be obtained.

  5. A self-constrained inversion of magnetic data based on correlation method

    Science.gov (United States)

    Sun, Shida; Chen, Chao

    2016-12-01

    Geologically-constrained inversion is a powerful method for producing geologically reasonable solutions in geophysical exploration problems. But in many cases, except the observed geophysical data to be inverted, the geological information is insufficiently available for improving reliability of recovered models. To deal with these situations, self-constraints extracted from preprocessing observed data have been applied to constrain the inversion. In this paper, we present a self-constrained inversion method based on correlation method. In our approach the correlation results are first obtained by calculating the cross-correlation between theoretical data and horizontal gradients of the observed data. Subsequently, we propose two specific strategies to extract the spatial variation from the correlation results and then translate them into spatial weighting functions. Incorporating the spatial weighting functions into the model objective function, we obtain self-constrained solutions with higher reliability. We presented two synthetic and one field magnetic data example to test the validity. All results demonstrate that the solution from our self-constrained inversion can delineate the geological bodies with clearer boundaries and much more concentrated physical property.

  6. A Novel Three-Head Ultrasonic System for Distance Measurements Based on the Correlation Method

    Directory of Open Access Journals (Sweden)

    Gądek Krzysztof

    2014-12-01

    Full Text Available A novel double-emitter ultrasonic system for distance measurements based on the correlation method is presented. The proposed distance measurement method may be particularly useful in difficult conditions, e.g. for media parameters undergoing fast changes or in cases when obstacles and mechanical interference produce false reflections. The system is a development of a previously studied single-head idea. The present article covers a comparison of the two systems in terms of efficiency and precision. Experimental research described in this paper indicated that adding the second head improved the measurement exactness – standard deviation decreased by 40%. The correlation method is also described in detail, also giving the criterion for the quality of the measurement signal.

  7. Determination of Material for Shaft Design Using on Grey Correlation Analysis and TOPSIS Method

    Directory of Open Access Journals (Sweden)

    B. Siva Kumar

    2015-10-01

    Full Text Available Machines, automobiles, aircrafts and many other applications have shaft as major mechanical component which must have a proper design, in-order to have the efficient transmission of power from one element to another. For the design of shaft an appropriate range of evaluation, general product form and processing methods for material must be made. The selection of material should be done by using multiple attribute decision methods (MADM. In this paper, Grey Correlation Analysis and TOPSIS Method is proposed in order to decide a suitable material by considering different attributes and graphical representations are made for different attributes verse materials and vice versa.

  8. An estimation method of the fault wind turbine power generation loss based on correlation analysis

    Science.gov (United States)

    Zhang, Tao; Zhu, Shourang; Wang, Wei

    2017-01-01

    A method for estimating the power generation loss of a fault wind turbine is proposed in this paper. In this method, the wind speed is estimated and the estimated value of the loss of power generation is given by combining the actual output power characteristic curve of the wind turbine. In the wind speed estimation, the correlation analysis is used, and the normal operation of the wind speed of the fault wind turbine is selected, and the regression analysis method is used to obtain the estimated value of the wind speed. Based on the estimation method, this paper presents an implementation of the method in the monitoring system of the wind turbine, and verifies the effectiveness of the proposed method.

  9. Gradient Correlation Method for the Stabilization of Inversion Results of Aerosol Microphysical Properties Retrieved from Profiles of Optical Data

    Directory of Open Access Journals (Sweden)

    Kolgotin Alexei

    2016-01-01

    Full Text Available Correlation relationships between aerosol microphysical parameters and optical data are investigated. The results show that surface-area concentrations and extinction coefficients are linearly correlated with a correlation coefficient above 0.99 for arbitrary particle size distribution. The correlation relationships that we obtained can be used as constraints in our inversion of optical lidar data. Simulation studies demonstrate a significant stabilization of aerosol microphysical data products if we apply the gradient correlation method in our traditional regularization technique.

  10. Investigation of Socially Responsible Investment Markets (SRI Using Dynamic Conditional Correlation (DCC Method: Implications for Diversification

    Directory of Open Access Journals (Sweden)

    Gurudeo Anand Tularam

    2010-01-01

    Full Text Available Problem statement: Over the last ten years there has been a phenomenal growth in the amount of funds placed in SRI globally estimated to be around US$6.5 trillion while around US$55 billion in the Australian market. Accurate knowledge of correlation of the Australian SRI market with other SRI markets overseas is crucially important for Australian (SRI investors for international portfolio diversification since portfolio diversification theory posits that the lower (higher the correlation between markets, the higher (lower the gains to be made. The study examines the relationship of the Australian SRI market with fourteen other markets-Canada, Denmark, France, Germany, Hong Kong, Ireland, Japan, Netherlands, Norway, South Africa, Sweden, Switzerland, United Kingdom and the United States. Approach: The relationships of the Australian Socially Responsible Investment (SRI market with other SRI markets worldwide during the period 1994-2009 are examined based on the dynamic conditional correlation multivariate GARCH model (DCCMVGarch. In the DCC method, the multivariate conditional variance estimation is simplified by estimating univariate GARCH models for each market. Using the transformed residuals resulting from the first stage, the authors can estimate a conditional correlation estimator. The standard errors for the first stage parameters remain while the standard errors for the correlation parameters are modified. Results: Our results showed that the Australian market experienced a surge in correlation with all other markets during the global financial crisis. During the period of study, the correlation of Australia with Canada, Denmark, Norway and the United Kingdom increased over time while its correlation with other countries remained stationary. This implies that the Australian SRI market is becoming more integrated with those of Canada, Denmark, Norway and the United Kingdom. Therefore, these overseas markets provide less

  11. Correlating thermal conductivity of pure hydrocarbons and aromatics via perceptron artificial neural network (PANN) method

    Institute of Scientific and Technical Information of China (English)

    Mostafa Lashkarbolooki; Ali Zeinolabedini Hezave; Mahdi Bayat

    2017-01-01

    Accurate estimation of liquid thermal conductivity is highly necessary to appropriately design equipments in dif-ferent industries. Respect to this necessity, in the current investigation a feed-forward artificial neural network (ANN) model is examined to correlate the liquid thermal conductivity of normal and aromatic hydrocarbons at the temperatures range of 257–338 K and atmospheric pressure. For this purpose, 956 experimental thermal con-ductivities for normal and aromatic hydrocarbons are collected from different previously published literature. During the modeling stage, to discriminate different substances, critical temperature (Tc), critical pressure (Pc) and acentric factor (ω) are utilized as the network inputs besides the temperature. During the examination, ef-fects of different transfer functions and number of neurons in hidden layer are investigated to find the optimum network architecture. Besides, statistical error analysis considering the results obtained from available correla-tions and group contribution methods and proposed neural network is performed to reliably check the feasibility and accuracy of the proposed method. Respect to the obtained results, it can be concluded that the proposed neu-ral network consisted of three layers namely, input, hidden and output layers with 22 neurons in hidden layer was the optimum ANN model. Generally, the proposed model enables to correlate the thermal conductivity of normal and aromatic hydrocarbons with absolute average relative deviation percent (AARD), mean square error (MSE), and correlation coefficient (R2) of lower than 0.2%, 1.05 × 10?7 and 0.9994, respectively.

  12. A WYNER-ZIV VIDEO CODING METHOD UTILIZING MIXTURE CORRELATION NOISE MODEL

    Institute of Scientific and Technical Information of China (English)

    Hu Xiaofei; Zhu Xiuchang

    2012-01-01

    In Wyner-Ziv (WZ) Distributed Video Coding (DVC),correlation noise model is often used to describe the error distribution between WZ frame and the side information.The accuracy of the model can influence the performance of the video coder directly.A mixture correlation noise model in Discrete Cosine Transform (DCT) domain for WZ video coding is established in this paper.Different correlation noise estimation method is used for direct current and alternating current coefficients.Parameter estimation method based on expectation maximization algorithm is used to estimate the Laplace distribution center of direct current frequency band and Mixture Laplace-Uniform Distribution Model (MLUDM) is established for alternating current coefficients.Experimental results suggest that the proposed mixture correlation noise model can describe the heavy tail and sudden change of the noise accurately at high rate and make significant improvement on the coding efficiency compared with the noise model presented by DIStributed COding for Video sERvices (DISCOVER).

  13. Investigation of real materials with strong electronic correlations by the LDA+DMFT method.

    Science.gov (United States)

    Anisimov, V I; Lukoyanov, A V

    2014-02-01

    Materials with strong electronic correlations are at the cutting edge of experimental and theoretical studies, capturing the attention of researchers for a great variety of interesting phenomena: metal-insulator, phase and magnetic spin transitions, `heavy fermion' systems, interplay between magnetic order and superconductivity, appearance and disappearance of local magnetic moments, and transport property anomalies. It is clear that the richness of physical phenomena for these compounds is a result of partially filled 3d, 4f or 5f electron shells with local magnetic moments preserved in the solid state. Strong interactions of d and f electrons with each other and with itinerant electronic states of the material are responsible for its anomalous properties. Electronic structure calculations for strongly correlated materials should explicitly take into account Coulombic interactions between d or f electrons. Recent advances in this field are related to the development of the LDA+DMFT method, which combines local density approximation (LDA) with dynamical mean-field theory (DMFT) to account for electronic correlation effects. In recent years, LDA+DMFT has allowed the successful treatment not only of simple systems but also of complicated real compounds. Nowadays, the LDA+DMFT method is the state-of-the-art tool for investigating correlated metals and insulators, spin and metal-insulator transitions (MIT) in transition-metal compounds in paramagnetic and magnetically ordered phases.

  14. Examples of the effects of different averaging methods on carbon dioxide fluxes calculated using the eddy correlation method

    Directory of Open Access Journals (Sweden)

    A. D. Culf

    2000-01-01

    Full Text Available Three hours of high frequency vertical windspeed and carbon dioxide concentration data recorded over tropical forest in Brazil are presented and discussed in relation to various detrending techniques used in eddy correlation analysis. Running means with time constants 100, 1000 and 1875s and a 30 minute linear detrend, as commonly used to determine fluxes, have been calculated for each case study and are presented. It is shown that, for different trends in the background concentration of carbon dioxide, the different methods can lead to the calculation of radically different fluxes over an hourly period. The examples emphasise the need for caution when interpreting eddy correlation derived fluxes especially for short term process studies. Keywords: Eddy covariance; detrending; running mean; carbon dioxide; tropical forest

  15. Probabilistic fracture investigation of symmetric angle ply laminated composite plates using displacement correlation method

    Directory of Open Access Journals (Sweden)

    Lal Achchhe

    2016-01-01

    Full Text Available The second order statistics of mixed mode stress intensity factors (MSIF of single edge V-notched angle ply laminated composite plate subjected to uniaxial tensile load with uncertinity in the system properties using displacement correlation method (DCM is evaluated. The random system properties such as material properties, crack opening and crack length are modelled as combined uncorrelated and correlated random system variables. A C0 finite element method (FEM based on higher order shear deformation plate theory (HSDT is used for basic formulation. The Taylor series based first order perturbation technique (FOPT, second order perturbation technique (SOPT are used and direct Monte Carlo simulation (MCS is performed to evaluate the statistics (mean and coefficient of variance of the mixed mode SIFs. The present work signifies the accurate analysis of frature behaviour by influence of different random variables and fibre orientations on the fracture behaviour in angle ply laminates.

  16. Electronic properties of antiferromagnetic UBi2 metal by exact exchange for correlated electrons method

    Directory of Open Access Journals (Sweden)

    E Ghasemikhah

    2012-03-01

    Full Text Available This study investigated the electronic properties of antiferromagnetic UBi2 metal by using ab initio calculations based on the density functional theory (DFT, employing the augmented plane waves plus local orbital method. We used the exact exchange for correlated electrons (EECE method to calculate the exchange-correlation energy under a variety of hybrid functionals. Electric field gradients (EFGs at the uranium site in UBi2 compound were calculated and compared with the experiment. The EFGs were predicted experimentally at the U site to be very small in this compound. The EFG calculated by the EECE functional are in agreement with the experiment. The densities of states (DOSs show that 5f U orbital is hybrided with the other orbitals. The plotted Fermi surfaces show that there are two kinds of charges on Fermi surface of this compound.

  17. Statistical methods to evaluate the correlation between measured and calculated dose using quality assurance method in IMRT

    Directory of Open Access Journals (Sweden)

    Abdulhamid Chaikh

    2015-12-01

    Full Text Available Purpose: the objective of this study is to validate a procedure based on a statistical method to assess the agreement and the correlation between measured and calculated dose in the process of quality assurance (QA for Intensity-Modulated Radiation Therapy (IMRT.Patients and methods: 10 patients including 56 fields for head and neck cancer treatment were analyzed. For each patient, one treatment plan was generated using Eclipse TPS®. To compare the calculated dose with measured dose a CT-scan of solid water slabs (30 × 30 × 15 cm3 was used. The measurements were done for absolute dose by a pinpoint ionization chamber and 2D dose distributions using electronic portal imaging device dosimetry. Six criteria levels were applied for each case (3%, 3 mm, (4%, 3 mm, (5%, 3 mm, (4%, 4 mm, (5%, 4 mm and (5%, 5 mm. The normality of the data and the variance homogeneity were tested using Shapiro-Wilks test and Levene’s test, respectively. Wilcoxon signed-rank paired test was used to calculate p-value. Bland-Altman method was used to calculate the limit of agreement between calculated and measured doses and to draw a scatter plot. The correlation between calculated and measured doses was assessed using Spearman’s rank test.Results: The statistical tests indicate that the data do not fulfill normal distribution, p < 0.001 and had a homogenous variance, p = 0.85. The upper and lower limit of agreements for absolute dose measurements were 6.44% and -6.40%, respectively. Wilcoxon test indicated a significance difference between calculated and measured dose with ionization chamber, p = 0.01. Spearman’s test indicated a strong correlation between calculated and absolute measured dose, ρ = 0.99. Therefore, there is a lack of correlation between dose difference for absolute dose measurements and gamma passing rates for 2D dose measurements.Conclusion: the statistical tests showed that the common acceptance criteria’s using gamma evaluation are not able

  18. Analytic methods for the Percus-Yevick hard sphere correlation functions

    Directory of Open Access Journals (Sweden)

    D. Henderson

    2009-01-01

    Full Text Available The Percus-Yevick theory for hard spheres provides simple accurate expressions for the correlation functions that have proven exceptionally useful. A summary of the author's lecture notes concerning three methods of obtaining these functions are presented. These notes are original only in part. However, they contain some helpful steps and simplifications. The purpose of this paper is to make these notes more widely available.

  19. Correlation analysis of PCB and comparison of test-analysis model reduction methods

    Institute of Scientific and Technical Information of China (English)

    Xu Fei; Li Chuanri; Jiang Tongmin; Rong Shuanglong

    2014-01-01

    The validity of correlation analysis between finite element model (FEM) and modal test data is strongly affected by three factors, i.e., quality of excitation and measurement points in modal test, FEM reduction methods, and correlation check techniques. A new criterion based on modified mode participation (MMP) for choosing the best excitation point is presented. Comparison between this new criterion and mode participation (MP) criterion is made by using Case 1 with a simple printed circuit board (PCB). The result indicates that this new criterion produces better results. In Case 2, 35 measure-ment points are selected to perform modal test and correlation analysis while 9 selected in Case 3. System equivalent reduction expansion process (SEREP), modal assurance criteria (MAC), coordinate modal assurance criteria (CoMAC), pseudo orthogonality check (POC) and coordinate orthogonality check (CORTHOG) are used to show the error introduced by modal test in Cases 2 and 3. Case 2 shows that additional errors which cannot be identified by using CoMAC can be found by using CORTHOG. In both Cases 2 and 3, Guyan reduction, improved reduced system (IRS) method, SEREP and Hybrid reduction are compared for accuracy and robustness. The results suggest that the quality of the reduction process is problem dependent. However, the IRS method is an improvement over the Guyan reduction, and the Hybrid reduction is an improvement over the SEREP reduction.

  20. A cross-correlation method to search for gravitational wave bursts with AURIGA and Virgo

    Energy Technology Data Exchange (ETDEWEB)

    Bignotto, M; Cerdonio, M; Conti, L; Drago, M; Liguori, N [Dipartimento di Fisica, Universita di Padova, Via Marzolo 8, 35131 Padova (Italy); Bonaldi, M; Falferi, P; Vinante, A [Istituto di Fotonica e Nanotecnologie, CNR-Fondazione Bruno Kessler, I-38050 Povo (Trento) (Italy); Camarda, M [Dipartimento di Ingegneria Informatica, Universita di Padova, Via G. Gradenigo 6a, 35131 Padova (Italy); Longo, S; Ortolan, A [INFN, Laboratori Nazionali di Legnaro, 35020 Legnaro, Padova (Italy); Mezzena, R; Mion, A; Prodi, G A; Re, V; Salemi, F; Vitale, S [INFN, Gruppo Collegato di Trento, Sezione di Padova, I-38050 Povo, Trento (Italy); Taffarello, L; Vedovato, G; Zendri, J P [INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy)], E-mail: virginia.re@lnl.infn.it (and others)

    2008-06-07

    We present a method to search for transient gravitational waves using a network of detectors with different spectral and directional sensitivities: the interferometer Virgo and the bar detector AURIGA. The data analysis method is based on the measurements of the correlated energy in the network by means of a weighted cross-correlation. To limit the computational load, this coherent analysis step is performed around time-frequency coincident triggers selected by an excess power event trigger generator tuned at low thresholds. The final selection of gravitational wave candidates is performed by a combined cut on the correlated energy and on the significance as measured by the event trigger generator. The method has been tested on one day of data of AURIGA and Virgo during September 2005. The outcomes are compared to the results of a stand-alone time-frequency coincidence search. We discuss the advantages and the limits of this approach, in view of a possible future joint search between AURIGA and one interferometric detector.

  1. A Cross-correlation method to search for gravitational wave bursts with AURIGA and Virgo

    CERN Document Server

    Bignotto, M; Camarda, M; Cerdonio, M; Conti, L; Drago, M; Falferi, P; Liguori, N; Longo, S; Mezzena, R; Mion, A; Ortolan, A; Prodi, G A; Re, V; Salemi, F; Taffarello, L; Vedovato, G; Vinante, A; Vitale, S; Zendri, J P; Acernese, F; Alshourbagy, M; Amico, P; Antonucci, F; Aoudia, S; Astone, P; Avino, S; Baggio, L; Ballardin, G; Barone, F; Barsotti, L; Barsuglia, M; Bauer, T S; Bigotta, S; Birindelli, S; Boccara, C; Bondu, F; Bosi, L; Braccini, S; Bradaschia, C; Brillet, A; Brisson, V; Buskulic, D; Cagnoli, G; Calloni, E; Campagna, E; Carbognani, F; Cavalier, F; Cavalieri, R; Cella, G; Cesarini, E; Chassande-Mottin, E; Clapson, A C; Cleva, F; Coccia, E; Corda, C; Corsi, A; Cottone, F; Coulon, J P; Cuoco, E; D'Antonio, S; Dari, A; Dattilo, V; Davier, M; De Rosa, R; Del Prete, M; Di Fiore, L; Di Lieto, A; Di Paolo Emilio, M; Di Virgilio, A; Evans, M; Fafone, V; Ferrante, I; Fidecaro, F; Fiori, I; Flaminio, R; Fournier, J D; Frasca, S; Frasconi, F; Gammaitoni, L; Garufi, F; Genin, E; Gennai, A; Giazotto, A; Giordano, L; Granata, V; Greverie, C; Grosjean, D; Guidi, G; Hamdani, S; Hebri, S; Heitmann, H; Hello, P; Huet, D; Kreckelbergh, S; La Penna, P; Laval, M

    2008-01-01

    We present a method to search for transient GWs using a network of detectors with different spectral and directional sensitivities: the interferometer Virgo and the bar detector AURIGA. The data analysis method is based on the measurements of the correlated energy in the network by means of a weighted cross-correlation. To limit the computational load, this coherent analysis step is performed around time-frequency coincident triggers selected by an excess power event trigger generator tuned at low thresholds. The final selection of GW candidates is performed by a combined cut on the correlated energy and on the significance as measured by the event trigger generator. The method has been tested on one day of data of AURIGA and Virgo during September 2005. The outcomes are compared to the results of a stand-alone time-frequency coincidence search. We discuss the advantages and the limits of this approach, in view of a possible future joint search between AURIGA and one interferometric detector.

  2. Local Correlation Calculations Using Standard and Renormalized Coupled-Cluster Methods

    Science.gov (United States)

    Piecuch, Piotr; Li, Wei; Gour, Jeffrey

    2009-03-01

    Local correlation variants of the coupled-cluster (CC) theory with singles and doubles (CCSD) and CC methods with singles, doubles, and non-iterative triples, including CCSD(T) and the completely renormalized CR-CC(2,3) approach, are developed. The main idea of the resulting CIM-CCSD, CIM-CCSD(T), and CIM-CR-CC(2,3) methods is the realization of the fact that the total correlation energy of a large system can be obtained as a sum of contributions from the occupied orthonormal localized molecular orbitals and their respective occupied and unoccupied orbital domains. The CIM-CCSD, CIM-CCSD(T), and CIM-CR-CC(2,3) algorithms are characterized by the linear scaling of the total CPU time with the system size and embarrassing parallelism. By comparing the results of the canonical and CIM-CC calculations for normal alkanes and water clusters, it is demonstrated that the CIM-CCSD, CIM-CCSD(T), and CIM-CR-CC(2,3) approaches recover the corresponding canonical CC correlation energies to within 0.1 % or so, while offering savings in the computer effort by orders of magnitude. By examining the dissociation of dodecane into C11H23 and CH3 and several lowest-energy structures of the (H2O)n clusters, it is shown that the CIM-CC methods accurately reproduce the relative energetics of the corresponding canonical CC calculations.

  3. Correlation analysis of PCB and comparison of test-analysis model reduction methods

    Directory of Open Access Journals (Sweden)

    Xu Fei

    2014-08-01

    Full Text Available The validity of correlation analysis between finite element model (FEM and modal test data is strongly affected by three factors, i.e., quality of excitation and measurement points in modal test, FEM reduction methods, and correlation check techniques. A new criterion based on modified mode participation (MMP for choosing the best excitation point is presented. Comparison between this new criterion and mode participation (MP criterion is made by using Case 1 with a simple printed circuit board (PCB. The result indicates that this new criterion produces better results. In Case 2, 35 measurement points are selected to perform modal test and correlation analysis while 9 selected in Case 3. System equivalent reduction expansion process (SEREP, modal assurance criteria (MAC, coordinate modal assurance criteria (CoMAC, pseudo orthogonality check (POC and coordinate orthogonality check (CORTHOG are used to show the error introduced by modal test in Cases 2 and 3. Case 2 shows that additional errors which cannot be identified by using CoMAC can be found by using CORTHOG. In both Cases 2 and 3, Guyan reduction, improved reduced system (IRS method, SEREP and Hybrid reduction are compared for accuracy and robustness. The results suggest that the quality of the reduction process is problem dependent. However, the IRS method is an improvement over the Guyan reduction, and the Hybrid reduction is an improvement over the SEREP reduction.

  4. Entropy correlation distance method. The Euro introduction effect on the Consumer Price Index

    Science.gov (United States)

    Miśkiewicz, Janusz

    2010-04-01

    The idea of entropy was introduced in thermodynamics, but it can be used in time series analysis. There are various ways to define and measure the entropy of a system. Here the so called Theil index, which is often used in economy and finance, is applied as it were an entropy measure. In this study the time series are remapped through the Theil index. Then the linear correlation coefficient between the remapped time series is evaluated as a function of time and time window size and the corresponding statistical distance is defined. The results are compared with the the usual correlation distance measure for the time series themselves. As an example this entropy correlation distance method (ECDM) is applied to several series, as those of the Consumer Price Index (CPI) in order to test some so called globalisation processes. Distance matrices are calculated in order to construct two network structures which are next analysed. The role of two different time scales introduced by the Theil index and a correlation coefficient is also discussed. The evolution of the mean distance between the most developed countries is presented and the globalisation periods of the prices discussed. It is finally shown that the evolution of mean distance between the most developed countries on several networks follows the process of introducing the European currency - the Euro. It is contrasted to the GDP based analysis. It is stressed that the entropy correlation distance measure is more suitable in detecting significant changes, like a globalisation process than the usual statistical (correlation based) measure.

  5. Double-layered target and identification method of individual target correlated with evaporation residues

    Energy Technology Data Exchange (ETDEWEB)

    Kaji, D., E-mail: daiya@riken.jp; Morimoto, K.

    2015-08-21

    A double-layered target system and an identification method (target ID) for individual targets mounted on a rotating wheel using correlation with evaporation residues were newly developed for the study of superheavy elements (SHE). The target system can be used in three modes: conventional single-layered mode, double-layered mode, and energy-degrader mode. The target ID method can be utilized for masking a target, measuring an excitation function without changing the beam energy from the accelerator, and searching for SHE nuclides using multiple targets during a single irradiation.

  6. Singlet-triplet gaps in substituted carbenes predicted from block-correlated coupled cluster method

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The block correlated coupled cluster (BCCC) method, with the complete active-space self-consistent-field (CASSCF) reference function, has been applied to investigating the singlet-triplet gaps in several substituted carbenes including four halocarbenes (CHCl, CF2, CCl2, and CBr2) and two hydroxycar-benes (CHOH and C(OH)2). A comparison of our results with the experimental data and other theoretical estimates shows that the present approach can provide quantitative descriptions for all the studied carbenes. It is demonstrated that the CAS-BCCC method is a promising theoretical tool for calculating the electronic structures of diradicals.

  7. Increasing the computational efficient of digital cross correlation by a vectorization method

    Science.gov (United States)

    Chang, Ching-Yuan; Ma, Chien-Ching

    2017-08-01

    This study presents a vectorization method for use in MATLAB programming aimed at increasing the computational efficiency of digital cross correlation in sound and images, resulting in a speedup of 6.387 and 36.044 times compared with performance values obtained from looped expression. This work bridges the gap between matrix operations and loop iteration, preserving flexibility and efficiency in program testing. This paper uses numerical simulation to verify the speedup of the proposed vectorization method as well as experiments to measure the quantitative transient displacement response subjected to dynamic impact loading. The experiment involved the use of a high speed camera as well as a fiber optic system to measure the transient displacement in a cantilever beam under impact from a steel ball. Experimental measurement data obtained from the two methods are in excellent agreement in both the time and frequency domain, with discrepancies of only 0.68%. Numerical and experiment results demonstrate the efficacy of the proposed vectorization method with regard to computational speed in signal processing and high precision in the correlation algorithm. We also present the source code with which to build MATLAB-executable functions on Windows as well as Linux platforms, and provide a series of examples to demonstrate the application of the proposed vectorization method.

  8. Investigation of spatial correlation in MR images of human cerebral white matter using geostatistical methods

    Energy Technology Data Exchange (ETDEWEB)

    Keil, Fabian

    2014-03-20

    Investigating the structure of human cerebral white matter is gaining interest in the neurological as well as in the neuroscientific community. It has been demonstrated in many studies that white matter is a very dynamic structure, rather than a static construct which does not change for a lifetime. That means, structural changes within white matter can be observed even on short timescales, e.g. in the course of normal ageing, neurodegenerative diseases or even during learning processes. To investigate these changes, one method of choice is the texture analysis of images obtained from white matter. In this regard, MRI plays a distinguished role as it provides a completely non-invasive way of acquiring in vivo images of human white matter. This thesis adapted a statistical texture analysis method, known as variography, to quantify the spatial correlation of human cerebral white matter based on MR images. This method, originally introduced in geoscience, relies on the idea of spatial correlation in geological phenomena: in naturally grown structures near things are correlated stronger to each other than distant things. This work reveals that the geological principle of spatial correlation can be applied to MR images of human cerebral white matter and proves that variography is an adequate method to quantify alterations therein. Since the process of MRI data acquisition is completely different to the measuring process used to quantify geological phenomena, the variographic analysis had to be adapted carefully to MR methods in order to provide a correctly working methodology. Therefore, theoretical considerations were evaluated with numerical samples in a first, and validated with real measurements in a second step. It was shown that MR variography facilitates to reduce the information stored in the texture of a white matter image to a few highly significant parameters, thereby quantifying heterogeneity and spatial correlation distance with an accuracy better than 5

  9. An efficient method for solving a correlated multi-item inventory system

    CERN Document Server

    Lee, Chang-Yong

    2014-01-01

    We propose an efficient method of finding an optimal solution for a multi-item continuous review inventory model in which a bivariate Gaussian probability distribution represents a correlation between the demands of different items. By utilizing appropriate normalizations of the demands, we show that the normalized demands are uncorrelated. Furthermore, the set of equations coupled with different items can be decoupled in such a way that the order quantity and reorder point for each item can be evaluated independently from those of the other. As a result, in contrast to conventional methods, the solution procedure for the proposed method can be much simpler and more accurate without any approximation. To demonstrate the advantage of the proposed method, we present a solution scheme for a multi-item continuous review inventory model in which the demand of optional components depend on that of a "vanilla box", representing the customer's stochastic demand, under stochastic payment and budget constraints. We als...

  10. Selection of an Optimal Method for Calculation of Correlated Color Temperature

    Directory of Open Access Journals (Sweden)

    Zheleznikova О. Ye.

    2016-04-01

    Full Text Available The article is dedicated to estimation of absolute errors in the methods of correlated color temperature (CCT calculation, namely the methods of Robertson (1968, McCamy (1992, Yoshi Ohno (2013, Javier Hernandez (1999 by means of the program developed by the authors. The work represents graphs of the absolute error distribution across the range of CCT definition. The authors outlined recommendations on use of the above methods in the colorimetric measurement practice based on the obtained results. The work also contains comparison of the “standard” variant of the Robertson’s method using 31 isotherms and the variants using more isotherms. It was demonstrated that with reduction of the period between isotherms the error tends to decrease. The calculation program was implemented with use of Python language and Numpy library, the tables were also computed by means of Python language and Scipy library, the graphs were plotted with the help of Matplotlib library.

  11. Identification of the elastic stiffness of composites using the virtual fields method and digital image correlation

    Science.gov (United States)

    Jiang, Lebin; Guo, Baoqiao; Xie, Huimin

    2015-04-01

    This paper presents an effective methodology for characterizing the mechanical parameters of composites using digital image correlation combined with the virtual fields method. By using a three-point bending test configuration, this method can identify all mechanical parameters of the material with merely a single test. Successful results verified that this method is especially effective for characterizing composite materials. In this study, the method is applied to measure the orthotropic elastic parameters of fiber-reinforced polymer-matrix composites before and after the hygrothermal aging process. The results indicate that the hygrothermal aging environment significantly influences the mechanical property of a composite. The components of the parameters in the direction of the fiber bundle decreased significantly. From the accuracy analysis, we found that the actual measurement accuracy is sensitive to a shift of the horizontal edges and rotation of the vertical edges.

  12. Inter-subject correlation in fMRI: method validation against stimulus-model based analysis.

    Directory of Open Access Journals (Sweden)

    Juha Pajula

    Full Text Available Within functional magnetic resonance imaging (fMRI, the use of the traditional general linear model (GLM based analysis methods is often restricted to strictly controlled research setups requiring a parametric activation model. Instead, Inter-Subject Correlation (ISC method is based on voxel-wise correlation between the time series of the subjects, which makes it completely non-parametric and thus suitable for naturalistic stimulus paradigms such as movie watching. In this study, we compared an ISC based analysis results with those of a GLM based in five distinct controlled research setups. We used International Consortium for Brain Mapping functional reference battery (FRB fMRI data available from the Laboratory of Neuro Imaging image data archive. The selected data included measurements from 37 right-handed subjects, who all had performed the same five tasks from FRB. The GLM was expected to locate activations accurately in FRB data and thus provide good grounds for investigating relationship between ISC and stimulus induced fMRI activation. The statistical maps of ISC and GLM were compared with two measures. The first measure was the Pearson's correlation between the non-thresholded ISC test-statistics and absolute values of the GLM Z-statistics. The average correlation value over five tasks was 0.74. The second was the Dice index between the activation regions of the methods. The average Dice value over the tasks and three threshold levels was 0.73. The results of this study indicated how the data driven ISC analysis found the same foci as the model-based GLM analysis. The agreement of the results is highly interesting, because ISC is applicable in situations where GLM is not suitable, for example, when analyzing data from a naturalistic stimuli experiment.

  13. Method of frequency dependent correlations: investigating the variability of total solar irradiance

    Science.gov (United States)

    Pelt, J.; Käpylä, M. J.; Olspert, N.

    2017-03-01

    Context. This paper contributes to the field of modeling and hindcasting of the total solar irradiance (TSI) based on different proxy data that extend further back in time than the TSI that is measured from satellites. Aims: We introduce a simple method to analyze persistent frequency-dependent correlations (FDCs) between the time series and use these correlations to hindcast missing historical TSI values. We try to avoid arbitrary choices of the free parameters of the model by computing them using an optimization procedure. The method can be regarded as a general tool for pairs of data sets, where correlating and anticorrelating components can be separated into non-overlapping regions in frequency domain. Methods: Our method is based on low-pass and band-pass filtering with a Gaussian transfer function combined with de-trending and computation of envelope curves. Results: We find a major controversy between the historical proxies and satellite-measured targets: a large variance is detected between the low-frequency parts of targets, while the low-frequency proxy behavior of different measurement series is consistent with high precision. We also show that even though the rotational signal is not strongly manifested in the targets and proxies, it becomes clearly visible in FDC spectrum. A significant part of the variability can be explained by a very simple model consisting of two components: the original proxy describing blanketing by sunspots, and the low-pass-filtered curve describing the overall activity level. The models with the full library of the different building blocks can be applied to hindcasting with a high level of confidence, Rc ≈ 0.90. The usefulness of these models is limited by the major target controversy. Conclusions: The application of the new method to solar data allows us to obtain important insights into the different TSI modeling procedures and their capabilities for hindcasting based on the directly observed time intervals.

  14. Taguchi Method for Development of Mass Flow Rate Correlation using Hydrocarbon Refrigerant Mixture in Capillary Tube

    Directory of Open Access Journals (Sweden)

    Shodiya Sulaimon

    2014-07-01

    Full Text Available The capillary tube is an important control device used in small vapor compression refrigeration systems such as window air-conditioners, household refrigerators and freezers. This paper develops a non-dimensional correlation based on the test results of the adiabatic capillary tube for the mass flow rate through the tube using a hydrocarbon refrigerant mixture of 89.3% propane and 10.7% butane (HCM. The Taguchi method, a statistical experimental design approach, was employed. This approach explores the economic benefit that lies in studies of this nature, where only a small number of experiments are required and yet valid results are obtained. Considering the effects of the capillary tube geometry and the inlet condition of the tube, dimensionless parameters were chosen. The new correlation was also based on the Buckingham Pi theorem. This correlation predicts 86.67% of the present experimental data within a relative deviation of -10% to +10%. The predictions by this correlation were also compared with results in published literature.

  15. Applying partial correlation method to analyzing the correlation between ionospheric NmF2 and height of isobaric level in the lower atmosphere

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    On the basis of a multiple linear regression model performed for ionospheric NmF2, partial correlation method is first applied to investigating the relation between NmF2 and h (the height of isobaric level) in the lower atmosphere over Wuhan, China during 1957―2004. The results show that partial correlation method can eliminate the influences of solar and geomagnetic activities as well as the seasonal variation factors and reveal the true correlation between NmF2 and h in the lower atmosphere. A weak positive correlation between NmF2 and h is found in the middle stratosphere. In addition, by comparing the partial correlation coefficients between NmF2 and its influence factors, we find that NmF2 is mainly affected by solar activity and the seasonal variation factors, and weakly affected by geomagnetic activity, but hardly affected by h in the lower atmosphere. The study suggests that partial correlation method is a helpful tool for investigating the correlation between ionospheric parameter and its influence factors.

  16. Prediction of shear wave velocity using empirical correlations and artificial intelligence methods

    Science.gov (United States)

    Maleki, Shahoo; Moradzadeh, Ali; Riabi, Reza Ghavami; Gholami, Raoof; Sadeghzadeh, Farhad

    2014-06-01

    Good understanding of mechanical properties of rock formations is essential during the development and production phases of a hydrocarbon reservoir. Conventionally, these properties are estimated from the petrophysical logs with compression and shear sonic data being the main input to the correlations. This is while in many cases the shear sonic data are not acquired during well logging, which may be for cost saving purposes. In this case, shear wave velocity is estimated using available empirical correlations or artificial intelligent methods proposed during the last few decades. In this paper, petrophysical logs corresponding to a well drilled in southern part of Iran were used to estimate the shear wave velocity using empirical correlations as well as two robust artificial intelligence methods knows as Support Vector Regression (SVR) and Back-Propagation Neural Network (BPNN). Although the results obtained by SVR seem to be reliable, the estimated values are not very precise and considering the importance of shear sonic data as the input into different models, this study suggests acquiring shear sonic data during well logging. It is important to note that the benefits of having reliable shear sonic data for estimation of rock formation mechanical properties will compensate the possible additional costs for acquiring a shear log.

  17. Prediction of shear wave velocity using empirical correlations and artificial intelligence methods

    Directory of Open Access Journals (Sweden)

    Shahoo Maleki

    2014-06-01

    Full Text Available Good understanding of mechanical properties of rock formations is essential during the development and production phases of a hydrocarbon reservoir. Conventionally, these properties are estimated from the petrophysical logs with compression and shear sonic data being the main input to the correlations. This is while in many cases the shear sonic data are not acquired during well logging, which may be for cost saving purposes. In this case, shear wave velocity is estimated using available empirical correlations or artificial intelligent methods proposed during the last few decades. In this paper, petrophysical logs corresponding to a well drilled in southern part of Iran were used to estimate the shear wave velocity using empirical correlations as well as two robust artificial intelligence methods knows as Support Vector Regression (SVR and Back-Propagation Neural Network (BPNN. Although the results obtained by SVR seem to be reliable, the estimated values are not very precise and considering the importance of shear sonic data as the input into different models, this study suggests acquiring shear sonic data during well logging. It is important to note that the benefits of having reliable shear sonic data for estimation of rock formation mechanical properties will compensate the possible additional costs for acquiring a shear log.

  18. Correlation mapping method of OCT for visualization blood vessels in brain

    Science.gov (United States)

    Izotova, O. A.; Kalyanov, A. L.; Lychagov, V. V.; Semyachkina-Glushkovskaya, O. V.

    2013-11-01

    The burning issue in modern medicine is the diagnosis and treatment of various life-threatening diseases, in particular the diseases of brain. One of them is intracranial hemorrhage (ICH). It occurs especially among newborn babies and is hard-diagnosed. In order to understand the nature of the ICH, the microcirculation of blood, which serves key functions within the body, is analyzed. On this basis a series of experiments was done, in the results of which it was showed, that latent stage of ICH is characterized by decrease of venous blood outflow and the loss of sensitivity of sagittal vein to vasoconstrictor effect of adrenaline. So, stress-related changes of the cerebral venous blood flow (CVBF) can be the source of this disease. In this paper registration CVBF was made with the help of commercially available Thorlabs Swept Source OCT System, using the correlation mapping method. In this method values of correlation coefficient of several images are analyzed. In the result of the algorithm the correlation map was obtained. By the resulting map the diameter of vessels was calculated, which is necessary for examination of effects of adrenalin to the vessels and identification symptoms of ICH.

  19. An autonomous surface discontinuity detection and quantification method by digital image correlation and phase congruency

    Science.gov (United States)

    Cinar, A. F.; Barhli, S. M.; Hollis, D.; Flansbjer, M.; Tomlinson, R. A.; Marrow, T. J.; Mostafavi, M.

    2017-09-01

    Digital image correlation has been routinely used to measure full-field displacements in many areas of solid mechanics, including fracture mechanics. Accurate segmentation of the crack path is needed to study its interaction with the microstructure and stress fields, and studies of crack behaviour, such as the effect of closure or residual stress in fatigue, require data on its opening displacement. Such information can be obtained from any digital image correlation analysis of cracked components, but it collection by manual methods is quite onerous, particularly for massive amounts of data. We introduce the novel application of Phase Congruency to detect and quantify cracks and their opening. Unlike other crack detection techniques, Phase Congruency does not rely on adjustable threshold values that require user interaction, and so allows large datasets to be treated autonomously. The accuracy of the Phase Congruency based algorithm in detecting cracks is evaluated and compared with conventional methods such as Heaviside function fitting. As Phase Congruency is a displacement-based method, it does not suffer from the noise intensification to which gradient-based methods (e.g. strain thresholding) are susceptible. Its application is demonstrated to experimental data for cracks in quasi-brittle (Granitic rock) and ductile (Aluminium alloy) materials.

  20. Tree Tensor Network State with Variable Tensor Order: An Efficient Multireference Method for Strongly Correlated Systems.

    Science.gov (United States)

    Murg, V; Verstraete, F; Schneider, R; Nagy, P R; Legeza, Ö

    2015-03-10

    We study the tree-tensor-network-state (TTNS) method with variable tensor orders for quantum chemistry. TTNS is a variational method to efficiently approximate complete active space (CAS) configuration interaction (CI) wave functions in a tensor product form. TTNS can be considered as a higher order generalization of the matrix product state (MPS) method. The MPS wave function is formulated as products of matrices in a multiparticle basis spanning a truncated Hilbert space of the original CAS-CI problem. These matrices belong to active orbitals organized in a one-dimensional array, while tensors in TTNS are defined upon a tree-like arrangement of the same orbitals. The tree-structure is advantageous since the distance between two arbitrary orbitals in the tree scales only logarithmically with the number of orbitals N, whereas the scaling is linear in the MPS array. It is found to be beneficial from the computational costs point of view to keep strongly correlated orbitals in close vicinity in both arrangements; therefore, the TTNS ansatz is better suited for multireference problems with numerous highly correlated orbitals. To exploit the advantages of TTNS a novel algorithm is designed to optimize the tree tensor network topology based on quantum information theory and entanglement. The superior performance of the TTNS method is illustrated on the ionic-neutral avoided crossing of LiF. It is also shown that the avoided crossing of LiF can be localized using only ground state properties, namely one-orbital entanglement.

  1. Numerical investigation of the High Temperature Reactor (VHTR) using computational fluid dynamics; Investigacao numerica do Reator de Alta Temperatura (VHTR) utilizando fluidodinamica computacional

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Joao Pedro C.T.A.; Santos, Andre A. Campagnole dos; Mesquita, Amir Z., E-mail: jpctap@cdtn.br, E-mail: aacs@cdtn.br, E-mail: amir@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG),Belo Horizonte, MG (Brazil). Lab. de Termo-Hidraulica

    2013-07-01

    This work consists to evaluate and continue the study that is being developed in the Laboratory of Thermo-Hydraulics of the CNEN/CDTN (Centro de Desenvolvimento da Tecnologia Nuclear), aiming to validate the methods and procedures used in the numerical calculations of fluid flow in fuel elements of the core of the VHTR.

  2. Studying the correlation between different word sense disambiguation methods and summarization effectiveness in biomedical texts

    Directory of Open Access Journals (Sweden)

    Díaz Alberto

    2011-08-01

    Full Text Available Abstract Background Word sense disambiguation (WSD attempts to solve lexical ambiguities by identifying the correct meaning of a word based on its context. WSD has been demonstrated to be an important step in knowledge-based approaches to automatic summarization. However, the correlation between the accuracy of the WSD methods and the summarization performance has never been studied. Results We present three existing knowledge-based WSD approaches and a graph-based summarizer. Both the WSD approaches and the summarizer employ the Unified Medical Language System (UMLS Metathesaurus as the knowledge source. We first evaluate WSD directly, by comparing the prediction of the WSD methods to two reference sets: the NLM WSD dataset and the MSH WSD collection. We next apply the different WSD methods as part of the summarizer, to map documents onto concepts in the UMLS Metathesaurus, and evaluate the summaries that are generated. The results obtained by the different methods in both evaluations are studied and compared. Conclusions It has been found that the use of WSD techniques has a positive impact on the results of our graph-based summarizer, and that, when both the WSD and summarization tasks are assessed over large and homogeneous evaluation collections, there exists a correlation between the overall results of the WSD and summarization tasks. Furthermore, the best WSD algorithm in the first task tends to be also the best one in the second. However, we also found that the improvement achieved by the summarizer is not directly correlated with the WSD performance. The most likely reason is that the errors in disambiguation are not equally important but depend on the relative salience of the different concepts in the document to be summarized.

  3. Using Correlation Adaptometry Method in Assessing Societal Stress: a Ukrainian Case

    CERN Document Server

    Rybnikov, Svyatoslav

    2012-01-01

    Societal stress may cause far reaching political, economic and even geological effects. Nevertheless, it is still scarcely investigated, contrary to social stress, which an individual faces in their interactions within a society. It is natural to suppose that in its adaptation, society demonstrates the same objective laws that biological population does, since they are, in fact, the closest systems. In the survey, the hypothesis is tested that the collective stress effect holds true in society, which must appear (as it happens according to correlation adaptometry method in biological systems) in escalation of both correlations between societal characteristics and their dispersion. Both tends are observed in Ukrainian society during 2009-2012, as a result of political elections that affect societal anxiety.

  4. A new method for correlation analysis of compositional (environmental) data - a worked example.

    Science.gov (United States)

    Reimann, C; Filzmoser, P; Hron, K; Kynčlová, P; Garrett, R G

    2017-12-31

    Most data in environmental sciences and geochemistry are compositional. Already the unit used to report the data (e.g., μg/l, mg/kg, wt%) implies that the analytical results for each element are not free to vary independently of the other measured variables. This is often neglected in statistical analysis, where a simple log-transformation of the single variables is insufficient to put the data into an acceptable geometry. This is also important for bivariate data analysis and for correlation analysis, for which the data need to be appropriately log-ratio transformed. A new approach based on the isometric log-ratio (ilr) transformation, leading to so-called symmetric coordinates, is presented here. Summarizing the correlations in a heat-map gives a powerful tool for bivariate data analysis. Here an application of the new method using a data set from a regional geochemical mapping project based on soil O and C horizon samples is demonstrated. Differences to 'classical' correlation analysis based on log-transformed data are highlighted. The fact that some expected strong positive correlations appear and remain unchanged even following a log-ratio transformation has probably led to the misconception that the special nature of compositional data can be ignored when working with trace elements. The example dataset is employed to demonstrate that using 'classical' correlation analysis and plotting XY diagrams, scatterplots, based on the original or simply log-transformed data can easily lead to severe misinterpretations of the relationships between elements. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Correlating the EMC analysis and testing methods for space systems in MIL-STD-1541A

    Science.gov (United States)

    Perez, Reinaldo J.

    1990-01-01

    A study was conducted to improve the correlation between the electromagnetic compatibility (EMC) analysis models stated in MIL-STD-1541A and the suggested testing methods used for space systems. The test and analysis methods outlined in MIL-STD-1541A are described, and a comparative assessment of testing and analysis techniques as they relate to several EMC areas is presented. Suggestions on present analysis and test methods are introduced to harmonize and bring the analysis and testing tools in MIL-STD-1541A into closer agreement. It is suggested that test procedures in MIL-STD-1541A must be improved by providing alternatives to the present use of shielded enclosures as the primary site for such tests. In addition, the alternate use of anechoic chambers and open field test sites must be considered.

  6. Deformation Study of Papandayan Volcano using GPS Survey Method and Its Correlation with Seismic Data Observation

    Directory of Open Access Journals (Sweden)

    Dina A. Sarsito

    2006-11-01

    Full Text Available Papandayan volcano located in the southern part of Garut regency, around 70 km away from Bandung city, West Java. Many methods carried out to monitoring the activities of volcano, both continuously or periodically, one of the monitoring method is periodically GPS survey. Basically those surveys are carried out to understand the pattern and velocity of displacement which occurred in the volcano body, both horizontally and vertically, and also others deformation elements such as; translation, rotation and dilatation. The Mogi modeling was also used to determine the location and volume of the pressure source which caused deformation of volcano body. By comparing seismic activity and the deformation reveal from GPS measurement, before, during and after eruption, it could be understood there is a correlation between the seismicity and its deformation. These studies is hoping that GPS measurement in Papandayan volcano could be one of supported method to determine the volcano activities, at least in Papandayan volcano.

  7. Practical approximation method for firing-rate models of coupled neural networks with correlated inputs

    Science.gov (United States)

    Barreiro, Andrea K.; Ly, Cheng

    2017-08-01

    Rapid experimental advances now enable simultaneous electrophysiological recording of neural activity at single-cell resolution across large regions of the nervous system. Models of this neural network activity will necessarily increase in size and complexity, thus increasing the computational cost of simulating them and the challenge of analyzing them. Here we present a method to approximate the activity and firing statistics of a general firing rate network model (of the Wilson-Cowan type) subject to noisy correlated background inputs. The method requires solving a system of transcendental equations and is fast compared to Monte Carlo simulations of coupled stochastic differential equations. We implement the method with several examples of coupled neural networks and show that the results are quantitatively accurate even with moderate coupling strengths and an appreciable amount of heterogeneity in many parameters. This work should be useful for investigating how various neural attributes qualitatively affect the spiking statistics of coupled neural networks.

  8. Computation of electronic structure and magnetic properties of strongly correlated materials with LDA+DMFT method

    Science.gov (United States)

    Skornyakov, S. L.; Anisimov, V. I.

    2015-04-01

    In this review, we describe general ideas of the LDA+DMFT method which merges dynamical mean-field theory (DMFT) and density functional theory (in particular the local density approximation (LDA)). Nowadays, the LDA+DMFT computational scheme is the most powerful numerical tool for studying physical properties of real materials and chemical compounds. It incorporates the advantage of DMFT to treat the full range of local dynamical Coulomb correlations and the ability of band methods to describe material-specific band dispersion caused by the lattice periodicity. We briefly discuss underlying physical ideas of LDA+DMFT and its mathematical implementation. Then different algorithms applied to solution of the DMFT impurity problem are briefly described. We then give examples of successful applications of the LDA+DMFT method to study spectral and magnetic properties of recently synthesized compounds like pnictide superconductors as well as classic charge-transfer systems NiO and MnO.

  9. Self-consistent implementation of ensemble density functional theory method for multiple strongly correlated electron pairs

    Science.gov (United States)

    Filatov, Michael; Liu, Fang; Kim, Kwang S.; Martínez, Todd J.

    2016-12-01

    The spin-restricted ensemble-referenced Kohn-Sham (REKS) method is based on an ensemble representation of the density and is capable of correctly describing the non-dynamic electron correlation stemming from (near-)degeneracy of several electronic configurations. The existing REKS methodology describes systems with two electrons in two fractionally occupied orbitals. In this work, the REKS methodology is extended to treat systems with four fractionally occupied orbitals accommodating four electrons and self-consistent implementation of the REKS(4,4) method with simultaneous optimization of the orbitals and their fractional occupation numbers is reported. The new method is applied to a number of molecular systems where simultaneous dissociation of several chemical bonds takes place, as well as to the singlet ground states of organic tetraradicals 2,4-didehydrometaxylylene and 1,4,6,9-spiro[4.4]nonatetrayl.

  10. Digital image correlation method for calculating coefficients of Williams expansion in compact tension specimen

    Science.gov (United States)

    Ayatollahi, Majid R.; Moazzami, Mostafa

    2017-03-01

    The digital image correlation (DIC) method is used to obtain the coefficients of higher-order terms in the Williams expansion in a compact tension (CT) specimens made of polymethyl methacrylate (PMMA). The displacement field is determined by the correlation between reference image (i.e., before deformation) and deformed image. The part of displacements resulting from rigid body motion and rotation is eliminated from the displacement field. For a large number of points in the vicinity of the crack tip, an over-determined set of simultaneous linear equations is collected, and by using the fundamental concepts of the least-squares method, the coefficients of the Williams expansion are calculated for pure mode I conditions. The experimental results are then compared with the numerical results calculated by finite element method (FEM). Very good agreement is shown to exist between the DIC and FE results confirming the effectiveness of the DIC technique in obtaining the coefficients of higher order terms of Williams series expansion from the displacement field around the crack tip.

  11. HORIZONTAL FLOWS IN ACTIVE REGIONS FROM RING-DIAGRAM AND LOCAL CORRELATION TRACKING METHODS

    Energy Technology Data Exchange (ETDEWEB)

    Jain, Kiran; Tripathy, S. C.; Komm, R.; Hill, F. [National Solar Observatory, 950 N Cherry Avenue, Tucson, AZ 85719 (United States); Ravindra, B., E-mail: kjain@nso.edu [Indian Institute of Astrophysics, Block 2, Koramangala, Bangaluru, 560034 (India)

    2016-01-01

    Continuous high-cadence and high spatial resolution Dopplergrams allow us to study subsurface dynamics that may be further extended to explore precursors of visible solar activity on the surface. Since the p-mode power is absorbed in the regions of high magnetic field, the inferences in these regions are often presumed to have large uncertainties. In this paper, using the Dopplergrams from space-borne Helioseismic Magnetic Imager, we compare horizontal flows in a shear layer below the surface and the photospheric layer in and around active regions. The photospheric flows are calculated using the local correlation tracking (LCT) method, while the ring-diagram technique of helioseismology is used to infer flows in the subphotospheric shear layer. We find a strong positive correlation between flows from both methods near the surface. This implies that despite the absorption of acoustic power in the regions of strong magnetic field, the flows inferred from the helioseismology are comparable to those from the surface measurements. However, the magnitudes are significantly different; the flows from the LCT method are smaller by a factor of 2 than the helioseismic measurements. Also, the median difference between the direction of corresponding vectors is 49°.

  12. Correlation Coefficients Between Different Methods of Expressing Bacterial Quantification Using Real Time PCR

    Directory of Open Access Journals (Sweden)

    Bahman Navidshad

    2012-02-01

    Full Text Available The applications of conventional culture-dependent assays to quantify bacteria populations are limited by their dependence on the inconsistent success of the different culture-steps involved. In addition, some bacteria can be pathogenic or a source of endotoxins and pose a health risk to the researchers. Bacterial quantification based on the real-time PCR method can overcome the above-mentioned problems. However, the quantification of bacteria using this approach is commonly expressed as absolute quantities even though the composition of samples (like those of digesta can vary widely; thus, the final results may be affected if the samples are not properly homogenized, especially when multiple samples are to be pooled together before DNA extraction. The objective of this study was to determine the correlation coefficients between four different methods of expressing the output data of real-time PCR-based bacterial quantification. The four methods were: (i the common absolute method expressed as the cell number of specific bacteria per gram of digesta; (ii the Livak and Schmittgen, ΔΔCt method; (iii the Pfaffl equation; and (iv a simple relative method based on the ratio of cell number of specific bacteria to the total bacterial cells. Because of the effect on total bacteria population in the results obtained using ΔCt-based methods (ΔΔCt and Pfaffl, these methods lack the acceptable consistency to be used as valid and reliable methods in real-time PCR-based bacterial quantification studies. On the other hand, because of the variable compositions of digesta samples, a simple ratio of cell number of specific bacteria to the corresponding total bacterial cells of the same sample can be a more accurate method to quantify the population.

  13. Simplified method for including spatial correlations in mean-field approximations

    Science.gov (United States)

    Markham, Deborah C.; Simpson, Matthew J.; Baker, Ruth E.

    2013-06-01

    Biological systems involving proliferation, migration, and death are observed across all scales. For example, they govern cellular processes such as wound healing, as well as the population dynamics of groups of organisms. In this paper, we provide a simplified method for correcting mean-field approximations of volume-excluding birth-death-movement processes on a regular lattice. An initially uniform distribution of agents on the lattice may give rise to spatial heterogeneity, depending on the relative rates of proliferation, migration, and death. Many frameworks chosen to model these systems neglect spatial correlations, which can lead to inaccurate predictions of their behavior. For example, the logistic model is frequently chosen, which is the mean-field approximation in this case. This mean-field description can be corrected by including a system of ordinary differential equations for pairwise correlations between lattice site occupancies at various lattice distances. In this work we discuss difficulties with this method and provide a simplification in the form of a partial differential equation description for the evolution of pairwise spatial correlations over time. We test our simplified model against the more complex corrected mean-field model, finding excellent agreement. We show how our model successfully predicts system behavior in regions where the mean-field approximation shows large discrepancies. Additionally, we investigate regions of parameter space where migration is reduced relative to proliferation, which has not been examined in detail before and find our method is successful at correcting the deviations observed in the mean-field model in these parameter regimes.

  14. Technical Note: Method to correlate whole-specimen histopathology of radical prostatectomy with diagnostic MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    McGrath, Deirdre M., E-mail: d.mcgrath@sheffield.ac.uk; Lee, Jenny; Foltz, Warren D. [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario M5G 2M9 (Canada); Samavati, Navid [Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9 (Canada); Jewett, Michael A. S. [Departments of Surgery (Urology) and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario M5G 2M9 (Canada); Kwast, Theo van der [Pathology Department, University Health Network, Toronto, Ontario M5G 2C4 (Canada); Chung, Peter [Radiation Medicine Program, Princess Margaret Hospital, University Health Network and the University of Toronto, Toronto, Ontario M5G 2M9 (Canada); Ménard, Cynthia [Radiation Medicine Program, Princess Margaret Hospital, University Health Network and the University of Toronto, Toronto, Ontario M5G 2M9, Canada and Centre Hospitalier de l’Université de Montréal, 1058 Rue Saint-Denis, Montréal, Québec H2X 3J4 (Canada); Brock, Kristy K. [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48108 (United States)

    2016-03-15

    Purpose: Validation of MRI-guided tumor boundary delineation for targeted prostate cancer therapy is achieved via correlation with gold-standard histopathology of radical prostatectomy specimens. Challenges to accurate correlation include matching the pathology sectioning plane with the in vivo imaging slice plane and correction for the deformation that occurs between in vivo imaging and histology. A methodology is presented for matching of the histological sectioning angle and position to the in vivo imaging slices. Methods: Patients (n = 4) with biochemical failure following external beam radiotherapy underwent diagnostic MRI to confirm localized recurrence of prostate cancer, followed by salvage radical prostatectomy. High-resolution 3-D MRI of the ex vivo specimens was acquired to determine the pathology sectioning angle that best matched the in vivo imaging slice plane, using matching anatomical features and implanted fiducials. A novel sectioning device was developed to guide sectioning at the correct angle, and to assist the insertion of reference dye marks to aid in histopathology reconstruction. Results: The percentage difference in the positioning of the urethra in the ex vivo pathology sections compared to the positioning in in vivo images was reduced from 34% to 7% through slicing at the best match angle. Reference dye marks were generated, which were visible in ex vivo imaging, in the tissue sections before and after processing, and in histology sections. Conclusions: The method achieved an almost fivefold reduction in the slice-matching error and is readily implementable in combination with standard MRI technology. The technique will be employed to generate datasets for correlation of whole-specimen prostate histopathology with in vivo diagnostic MRI using 3-D deformable registration, allowing assessment of the sensitivity and specificity of MRI parameters for prostate cancer. Although developed specifically for prostate, the method is readily

  15. Neutron Star masses from the Field Correlator Method Equation of State

    Directory of Open Access Journals (Sweden)

    Zappalà D.

    2014-04-01

    Full Text Available We analyse the hadron-quark phase transition in neutron stars by confronting the hadronic Equation of State (EoS obtained according to the microscopic Brueckner-Hartree-Fock many body theory, with the quark matter EoS derived within the Field Correlator Method. In particular, the latter EoS is only parametrized in terms of the gluon condensate and the large distance quark-antiquark potential, so that the comparison of the results of this analysis with the most recent measurements of heavy neutron star masses provides some physical constraints on these two parameters.

  16. Interaction of Shock Waves in Cement Mortar Plate Investigated by the Digital Speckle Correlation Method

    Institute of Scientific and Technical Information of China (English)

    LI Xu-Dong; LIU Kai-Xin; ZHANG Guang-Sheng; WEN Shang-Gang; TAN Fu-Li

    2008-01-01

    @@ Interaction of shock waves in cement mortar plate is studied by digital speckle correlation method and digital high-speed photography technique. When the plates were destroyed by two detonators exploding at the same time, variation of shock wave field is obtained. Experimental results show that the interaction of shock waves will result in a nonlinear huge increase of local normal strain, leading to large deformation and serious destruction. However, the occurrence of this strongly nonlinear phenomenon sensitively depends on the interval between detonators, and it will only appear when the interval is smaller than the diameter of the region where shock waves exist.

  17. Application of digital image correlation method for analysing crack variation of reinforced concrete beams

    Indian Academy of Sciences (India)

    Ming-Hsiang Shih; Wen-Pei Sung

    2013-08-01

    The Digital Image Correlation (DIC) method is a fast-growing emerging technology that provides a low-cost method for measuring the strain of an object. In this study, the feasibility of using this method to observe cracks developed in reinforced concrete beams will be explored so that a practical application can be proposed. The DIC method has been applied for analysing the field of surface displacement and strain; it is not applicable for measuring non-continuous field of displacement. However, if a singular point (i.e., crack points) can be considered as the area of concentrated strain by imitating the treatment of micro-cracks using the finite element method, the region of concentrated strain field based on analyses of digital images can be applied for determining the locations of cracks. Laboratory results show that cracks developed in reinforced cement beams can be observed with a good precision using the von Mises strain field, and that smaller grids lead to clearer crack images. In addition to identifying visible cracks, the DIC image analysis will enable researchers to identify minute cracks that are not visible to naked eyes. Additionally, the DIC method has more accuracy and precision than visual observation for analysing crack loadings so that earlier warnings can be realized before cracks develop in the specimen.

  18. Using Response Surface Methods to Correlate the Modal Test of an Inflatable Test Article

    Science.gov (United States)

    Gupta, Anju

    2013-01-01

    This paper presents a practical application of response surface methods (RSM) to correlate a finite element model of a structural modal test. The test article is a quasi-cylindrical inflatable structure which primarily consists of a fabric weave, with an internal bladder and metallic bulkheads on either end. To mitigate model size, the fabric weave was simplified by representing it with shell elements. The task at hand is to represent the material behavior of the weave. The success of the model correlation is measured by comparing the four major modal frequencies of the analysis model to the four major modal frequencies of the test article. Given that only individual strap material properties were provided and material properties of the overall weave were not available, defining the material properties of the finite element model became very complex. First it was necessary to determine which material properties (modulus of elasticity in the hoop and longitudinal directions, shear modulus, Poisson's ratio, etc.) affected the modal frequencies. Then a Latin Hypercube of the parameter space was created to form an efficiently distributed finite case set. Each case was then analyzed with the results input into RSM. In the resulting response surface it was possible to see how each material parameter affected the modal frequencies of the analysis model. If the modal frequencies of the analysis model and its corresponding parameters match the test with acceptable accuracy, it can be said that the model correlation is successful.

  19. Measuring electrophysiological connectivity by power envelope correlation: a technical review on MEG methods

    Science.gov (United States)

    O'Neill, George C.; Barratt, Eleanor L.; Hunt, Benjamin A. E.; Tewarie, Prejaas K.; Brookes, Matthew J.

    2015-11-01

    The human brain can be divided into multiple areas, each responsible for different aspects of behaviour. Healthy brain function relies upon efficient connectivity between these areas and, in recent years, neuroimaging has been revolutionised by an ability to estimate this connectivity. In this paper we discuss measurement of network connectivity using magnetoencephalography (MEG), a technique capable of imaging electrophysiological brain activity with good (~5 mm) spatial resolution and excellent (~1 ms) temporal resolution. The rich information content of MEG facilitates many disparate measures of connectivity between spatially separate regions and in this paper we discuss a single metric known as power envelope correlation. We review in detail the methodology required to measure power envelope correlation including (i) projection of MEG data into source space, (ii) removing confounds introduced by the MEG inverse problem and (iii) estimation of connectivity itself. In this way, we aim to provide researchers with a description of the key steps required to assess envelope based functional networks, which are thought to represent an intrinsic mode of coupling in the human brain. We highlight the principal findings of the techniques discussed, and furthermore, we show evidence that this method can probe how the brain forms and dissolves multiple transient networks on a rapid timescale in order to support current processing demand. Overall, power envelope correlation offers a unique and verifiable means to gain novel insights into network coordination and is proving to be of significant value in elucidating the neural dynamics of the human connectome in health and disease.

  20. Methods of estrus detection and correlates of the reproductive cycle in the sun bear (Helarctos malayanus).

    Science.gov (United States)

    Frederick, Cheryl; Kyes, Randall; Hunt, Kathleen; Collins, Darin; Durrant, Barbara; Wasser, Samuel K

    2010-10-15

    The objective was to explore multiple methods for detecting and characterizing the reproductive cycle of the sun bear (Helarctos malayanus). Thirteen H. m. euryspilus females, loaned from the Malaysian government to US zoos, were used. Fecal metabolite concentrations of estrogen and progesterone were compared to vaginal cytology, changes in genital appearance, and behavior (videotapes and zookeeper observations). Cytology and video behavior were characterized during five hormonally defined states: high, low, and baseline progesterone, estrus, and high estrogen. Among states, there were significant differences in cytology and behavior. Sexual, affiliative, and stereotypic behaviors were highest during estrus, whereas affiliative and social behaviors were lowest during high progesterone. In this captive breeding population, 30.8% of females cycled two or three times a year, 30.8% cycled once a year, and 38.5% did not cycle during this study. Inter-estrus intervals were (mean ± SEM) 115.7 ± 6.3 d (range, 101-131). Spearman rank correlations were significant between both ordinal sexual and affiliative behaviors and vulva swelling and color. Sexual behavior was significantly positively correlated with superficial and keratinized cells, but negatively correlated with parabasal and basophilic cells in cycling females (opposite pattern for appetitive behavior). In conclusion, data for cytology, vulva changes and behavior were consistent with, and complementary to, hormonal data; collectively, they delineated estrus and identified specific reproductive types.

  1. Intercomparison of a correlated-photon-based method to measure detector quantum efficiency.

    Science.gov (United States)

    Migdall, Alan; Castelletto, Stefania; Degiovanni, Ivo Pietro; Rastello, Maria Luisa

    2002-05-20

    We report on the absolute calibration of photodetector quantum efficiency by using correlated photon sources, performed independently at two laboratories, the National Institute of Standards and Technology and the Istituto Elettrotecnico Nazionale (IEN). The goal is to use an interlaboratory comparison to demonstrate the inherent absoluteness of the photon correlation technique by showing its independence from the particular experimental setup. We find that detector nonuniformity limited this comparison rather than uncertainty inherent in the method itself. The ultimate goal of these investigations is development of a robust measurement protocol that allows the uncertainties of individual measurements to be determined experimentally and verified operationally. Furthermore, to demonstrate the generality of the procedure, the IEN measurement setup was also used to calibrate a fiber-coupled avalanche photodiode module. Uncertainties are evaluated for the detector both with and without fiber coupling and differences are discussed. The current IEN setup using a thinner and higher transmittance nonlinear crystal for the generation of correlated photons shows a significant improvement in overall accuracy with respect to previously reported results from IEN [Metrologia 32, 501-503 (1996)].

  2. Method of correlation function for analyzing cross-sensitivity of strain and temperature in fiber grating sensors

    Institute of Scientific and Technical Information of China (English)

    HAN Gui-hua; ZHANG Wei-gang

    2007-01-01

    A novel method of correlation function for analyzing cross-sensitivity between strain and temperature is reported for the first time in this paper. Using the new method, the correlative characteristics between strain and temperature of fiber Bragg grating sensors are studied both theoretically and experimentally The experimental results accord with the theoretical calculations.

  3. Empirical source strength correlations for rans-based acoustic analogy methods

    Science.gov (United States)

    Kube-McDowell, Matthew Tyndall

    JeNo is a jet noise prediction code based on an acoustic analogy method developed by Mani, Gliebe, Balsa, and Khavaran. Using the flow predictions from a standard Reynolds-averaged Navier-Stokes computational fluid dynamics solver, JeNo predicts the overall sound pressure level and angular spectra for high-speed hot jets over a range of observer angles, with a processing time suitable for rapid design purposes. JeNo models the noise from hot jets as a combination of two types of noise sources; quadrupole sources dependent on velocity fluctuations, which represent the major noise of turbulent mixing, and dipole sources dependent on enthalpy fluctuations, which represent the effects of thermal variation. These two sources are modeled by JeNo as propagating independently into the far-field, with no cross-correlation at the observer location. However, high-fidelity computational fluid dynamics solutions demonstrate that this assumption is false. In this thesis, the theory, assumptions, and limitations of the JeNo code are briefly discussed, and a modification to the acoustic analogy method is proposed in which the cross-correlation of the two primary noise sources is allowed to vary with the speed of the jet and the observer location. As a proof-of-concept implementation, an empirical correlation correction function is derived from comparisons between JeNo's noise predictions and a set of experimental measurements taken for the Air Force Aero-Propulsion Laboratory. The empirical correlation correction is then applied to JeNo's predictions of a separate data set of hot jets tested at NASA's Glenn Research Center. Metrics are derived to measure the qualitative and quantitative performance of JeNo's acoustic predictions, and the empirical correction is shown to provide a quantitative improvement in the noise prediction at low observer angles with no freestream flow, and a qualitative improvement in the presence of freestream flow. However, the results also demonstrate

  4. Gastroesophageal reflux - correlation between diagnostic methods; Refluxo gastroesofagico - correlacao entre metodos diagnosticos

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, Maria das Gracas de Almeida; Penas, Maria Exposito; Fonseca, Lea Mirian Barbosa [Universidade Federal, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina. Dept. de Radiologia-Medicina Nuclear; Lemme, Eponina Maria O. [Universidade Federal, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina. Dept. de Clinia Medica-Gastroenterologia; Martinho, Maria Jose Ribeiro [Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, RJ (Brazil). Servico de Medicina Nuclear

    1999-02-01

    A group of 97 individuals with typical symptoms of gastroesophageal reflux disease (GERD) was submitted to gastroesophageal reflux scintigraphy (GES) and compared to the results obtained from endoscopy, histopathology and 24 hours pHmetry. Twenty-four healthy individuals were used as a control group and they have done only the GERS. The results obtained showed that: (a) the difference in the reflux index (RI) for the control group and the sick individuals was statistically significant (p < 0.0001); (b) the correlation between GERS and the other methods showed the following results: sensitivity, 84%; specificity, 95%; positive predictive value, 98%; negative predictive value, 67%; accuracy, 87%. We have concluded that the scintigraphic method should be used to confirm the diagnosis of GERD and also recommended as initial investiative procedure. (author)

  5. Singlet-triplet gaps in substituted carbenes predicted from block-correlated coupled cluster method

    Institute of Scientific and Technical Information of China (English)

    SHEN Jun; FANG Tao; LI Shuhua

    2008-01-01

    Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, ChinaThe block correlated coupled cluster (BCCC) method, with the complete active-space self-consistent-field (CASSCF) reference function, has been applied to investigating the singlet-triplet gaps in several substituted carbenes including four halocarbenes (CHCl, CF2, CCl2, and CBr2) and two hydroxycar-bones (CHOH and C(OH)2). A comparison of our results with the experimental data and other theoretical estimates shows that the present approach can provide quantitative descriptions for all the studied carbenes. It is demonstrated that the CAS-BCCC method is a promising theoretical tool for calculating the electronic structures of diradicals.

  6. Correlation and prediction of environmental properties of alcohol ethoxylate surfactants using the UNIFAC method

    DEFF Research Database (Denmark)

    Cheng, Hongyuan; Kontogeorgis, Georgios; Stenby, Erling Halfdan

    2005-01-01

    Environmental properties of one type of nonionic surfactants, the alcohol ethoxylates (polyoxyethylene alcohols), are predicted using the UNIFAC (universal quasi-chemical functional group activity coefficient) method. Various properties are considered; the octanol-water partition coefficient (Kow......), the bioconcentration factor (BCF), and the toxicity. Kow values of alcohol ethoxylates are difficult to measure. Existing methods such as those in commercial software like ACD,ClogP and KowWin have not been applied to surfactants, and they fail for heavy alcohol ethoxylates (alkyl carbon numbers above 12). Thus......, the Kow values are predicted here via UNIFAC and compared to the few available experimental data. Based on the predicted Kow values, a correlation between Kow and hydrophilic-lipophilic balance (HLB) is establi2shed because HLB is a widely used parameter in surfactant applications. Finally, BCF...

  7. A LFP-tree based method for association rules mining in telecommunication alarm correlation analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The mining of association rules is one of the primary methods used in telecommunication alarm correlation analysis,of which the alarm databases are very large.The efficiency of the algorithms plays an important role in tackling with large datasets. The classical frequent pattern growth(FP-growth) algorithm can produce a large number of conditional pattern trees which made it difficult to mine association rules in are telecommunication environment.In this paper,an algorithm based on layered frequent pattern tree(LFP-tree) is proposed for mining frequent patterns. Efficiency of this alagorithm is achieved with following techniques:1) All the frequent patterns are condensed into a layered structure,which can save memory time but also be very useful for updating the alarm databases.2) Each alarm item can be viewed as a triple,in which t is a Boolean vaviable that shows the item frequent or not.3) Deleting infrequent items with dynamic pruning can avoid produce conditional pattern sets. Simulation and analysis of algorithm show that it is a valid method with better time and space efficiency,which is adapted to mine association rules in telecommunication alarm correlation analysis.

  8. Partial least squares methods: partial least squares correlation and partial least square regression.

    Science.gov (United States)

    Abdi, Hervé; Williams, Lynne J

    2013-01-01

    Partial least square (PLS) methods (also sometimes called projection to latent structures) relate the information present in two data tables that collect measurements on the same set of observations. PLS methods proceed by deriving latent variables which are (optimal) linear combinations of the variables of a data table. When the goal is to find the shared information between two tables, the approach is equivalent to a correlation problem and the technique is then called partial least square correlation (PLSC) (also sometimes called PLS-SVD). In this case there are two sets of latent variables (one set per table), and these latent variables are required to have maximal covariance. When the goal is to predict one data table the other one, the technique is then called partial least square regression. In this case there is one set of latent variables (derived from the predictor table) and these latent variables are required to give the best possible prediction. In this paper we present and illustrate PLSC and PLSR and show how these descriptive multivariate analysis techniques can be extended to deal with inferential questions by using cross-validation techniques such as the bootstrap and permutation tests.

  9. Joint Analysis Method for Major Genes Controlling Multiple Correlated Quantitative Traits

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Based on the major gene and polygene mixed inheritance model for multiple correlated quantitative traits, the authors proposed a new joint segregation analysis method of major gene controlling multiple correlated quantitative traits, which include major gene detection and its effect and variation estimation. The effect and variation of major gene are estimated by the maximum likelihood method implemented via expectation-maximization (EM) algorithm. Major gene is tested with the likelihood ratio (LR) test statistic. Extensive simulation studies showed that joint analysis not only increases the statistical power of major gene detection but also improves the precision and accuracy of major gene effect estimates. An example of the plant height and the number of tiller of F2 population in rice cross Duonieai × Zhonghua 11 was used in the illustration. The results indicated that the genetic difference of these two traits in this cross refers to only one pleiotropic major gene. The additive effect and dominance effect of the major gene are estimated as -21.3 and 40.6 cm on plant height, and 22.7 and -25.3 on number of tiller, respectively. The major gene shows overdominance for plant height and close to complete dominance for number of tillers.

  10. Horizontal Flows in Active Regions from Ring-diagram and Local Correlation Tracking Methods

    CERN Document Server

    Jain, Kiran; Ravindra, B; Komm, R; Hill, F

    2015-01-01

    Continuous high-cadence and high-spatial resolution Dopplergrams allow us to study sub-surface dynamics that may be further extended to explore precursors of visible solar activity on the surface. Since the p-mode power is absorbed in the regions of high magnetic field, the inferences in these regions are often presumed to have large uncertainties. In this paper, using the Dopplergrams from space-borne Helioseismic Magnetic Imager (HMI), we compare horizontal flows in a shear layer below the surface and the photospheric layer in and around active regions. The photospheric flows are calculated using local correlation tracking (LCT) method while the ring-diagram (RD) technique of helioseismology is used to infer flows in the sub-photospheric shear layer. We find a strong positive correlation between flows from both methods near the surface. This implies that despite the absorption of acoustic power in the regions of strong magnetic field, the flows inferred from the helioseismology are comparable to those from ...

  11. A wavelet-based method to discriminate internal faults from inrush currents using correlation coefficient

    Energy Technology Data Exchange (ETDEWEB)

    Vahidi, B.; Ghaffarzadeh, N.; Hosseinian, S.H. [Dept. of Electrical Engineering, Amirkabir University of Technology, Tehran (Iran)

    2010-09-15

    In this paper a new method based on discrete wavelet transform and correlation coefficient is presented for digital differential protection. The algorithm includes offline and online operations. In offline operation, discrete wavelet transform is used to decompose typical three-phase differential currents for inrush current. Then an index is defined and computed. The index is based on the sum of the energy of detail coefficients at level 5 of three-phase differential currents at each half cycle. The online operation consists of capturing the three-phase differential currents using 10 kHz sampling rate, decomposing it by db1. Finally, the inrush current and internal fault is detected based on correlation coefficients of the computed index of pre-stored typical inrush current and a recorded indistinct signal. The effectiveness of the approach is tested using numerous inrush and internal fault currents. Simulations are used to confirm the aptness and the capability of the proposed method to discriminate inrush current from internal fault. (author)

  12. Development of digital image correlation method to analyse crack variations of masonry wall

    Indian Academy of Sciences (India)

    Shih-Heng Tung; Ming-Hsiang Shih; Wen-Pei Sung

    2008-12-01

    The detection of crack development in a masonry wall forms an important study for investigating the earthquake resistance capability of the masonry structures. Traditionally, inspecting the structure and documenting the findings were done manually. The procedures are time-consuming, and the results are sometimes inaccurate. Therefore, the digital image correlation (DIC) technique is developed to identify the strain and crack variations. This technique is non-destructive for inspecting the whole displacement and strain field. Tests on two masonry wall samples were performed to verify the performance of the digital image correlation method. The phenomena of micro cracks, strain concentration situation and nonuniform deformation distribution which could not have been observed preciously by manual inspection are successfully identified using DIC. The crack formation tendencies on masonry wall can be observed at an earlier stage by this proposed method. These results show a great application potential of the DIC technique for various situations such as inspecting shrinkage-induced cracks in fresh concrete, masonry and reinforced concrete structures, and safety of bridges.

  13. A minimalistic approach to static and dynamic electron correlations: Amending generalized valence bond method with extended random phase approximation correlation correction

    Science.gov (United States)

    Chatterjee, Koushik; Pastorczak, Ewa; Jawulski, Konrad; Pernal, Katarzyna

    2016-06-01

    A perfect-pairing generalized valence bond (GVB) approximation is known to be one of the simplest approximations, which allows one to capture the essence of static correlation in molecular systems. In spite of its attractive feature of being relatively computationally efficient, this approximation misses a large portion of dynamic correlation and does not offer sufficient accuracy to be generally useful for studying electronic structure of molecules. We propose to correct the GVB model and alleviate some of its deficiencies by amending it with the correlation energy correction derived from the recently formulated extended random phase approximation (ERPA). On the examples of systems of diverse electronic structures, we show that the resulting ERPA-GVB method greatly improves upon the GVB model. ERPA-GVB recovers most of the electron correlation and it yields energy barrier heights of excellent accuracy. Thanks to a balanced treatment of static and dynamic correlation, ERPA-GVB stays reliable when one moves from systems dominated by dynamic electron correlation to those for which the static correlation comes into play.

  14. A Numerical Method to Study Highly Correlated Nanostructures: The Logarithmic Discretization Embedded Cluster Approximation

    Science.gov (United States)

    Anda, E.; Chiappe, G.; Busser, C.; Davidovich, M.; Martins, G.; H-Meisner, F.; Dagotto, E.

    2008-03-01

    A numerical algorithm to study transport properties of highly correlated local structures is proposed. The method, dubbed the Logarithmic Discretization Embedded Cluster Approximation (LDECA), consists of diagonalizing a finite cluster containing the many-body terms of the Hamiltonian and embedding it into the rest of the system, combined with Wilson's ideas of a logarithmic discretization of the representation of the Hamiltonian. LDECA's rapid convergence eliminates finite-size effects commonly present in the embedding cluster approximation (ECA) method. The physics associated with both one embedded dot and a string of two dots side-coupled to leads is discussed. In the former case, our results accurately agree with Bethe ansatz (BA) data, while in the latter, the results are framed in the conceptual background of a two-stage Kondo problem. A diagrammatic expansion provides the theoretical foundation for the method. It is argued that LDECA allows for the study of complex problems that are beyond the reach of currently available numerical methods.

  15. A novel acoustic method for gas flow measurement using correlation techniques

    Science.gov (United States)

    Knuuttila, Matti Tapani

    The study demonstrates a new kind of acoustic method for gas flow measurement. The method uses upstream and downstream propagating low frequency plane wave and correlation techniques for volume flow rate determination. The theory of propagating low frequency plane waves in the pipe is introduced and is proved empirically to be applicable for flow measurement. The flow profile dependence of the method is verified and found to be negligible at least in the region of moderate perturbations. The physical principles of the method were applied in practice in the form of a flowmeter with new design concepts. The developed prototype meters were verified against the reference standard of NMI (Nederlands Meetinstituut), which showed that a wide dynamic range of 1:80 is achievable with total expanded uncertainty below 0.3%. Also the requirements used for turbine meters of linearity, weighted mean error and stability were shown to be well fulfilled. A brief comparison with other flowmeter types shows the new flowmeter to be competitive. The advantages it offers are a small pressure drop over the meter, no blockage of flow in possible malfunction, no pulsation to flow, essentially no moving parts, and the possibility for bidirectional measurements. The introduced flowmeter is also capable of using the introduced flowmeter is also capable of using the telephone network or a radio-modem to read the consumption of gas and report its operation to the user.

  16. A novel acoustic method for gas flow measurement using correlation techniques

    Energy Technology Data Exchange (ETDEWEB)

    Knuuttila, M. [VTT Chemical Technology, Espoo (Finland). Industrial Physics

    1997-12-31

    The study demonstrates a new kind of acoustic method for gas flow measurement. The method uses upstream and downstream propagating low frequency plane wave and correlation techniques for volume flow rate determination. The theory of propagating low frequency plane waves in the pipe is introduced and is proved empirically to be applicable for flow measurement. The flow profile dependence of the method is verified and found to be negligible at least in the region of moderate perturbations. The physical principles of the method were applied in practice in the form of a flowmeter with new design concepts. The developed prototype meters were verified against the reference standard of NMI (Nederlands Meetinstituut), which showed that a wide dynamic range of 1:80 is achievable with total expanded uncertainty below 0.3 %. Also the requirements used for turbine meters of linearity, weighted mean error and stability were shown to be well fulfilled. A brief comparison with other flowmeter types shows the new flowmeter to be competitive. The advantages it offers are a small pressure drop over the meter, no blockage of flow in possible malfunction, no pulsation to flow, essentially no moving parts, and the possibility for bidirectional measurements. The introduced flowmeter is also capable of using the telephone network or a radio-modem to read the consumption of gas and report its operation to the user. (orig.) 51 refs.

  17. A time and space correlated turbulence synthesis method for Large Eddy Simulations

    Science.gov (United States)

    Castro, Hugo G.; Paz, Rodrigo R.

    2013-02-01

    In the present work the problem of generating synthesized turbulence at inflow boundaries of the simulation domain is addressed in the context of the Large Eddy Simulation (LES) method. To represent adequately certain statistical properties of a turbulent process, we propose a synthesized turbulence method which is based on previous works (Huang et al., 2010; Smirnov et al., 2001) [15,28]. For this purpose, time and space correlations are introduced strictly in the mathematical formulation of the synthetic turbulence inflow data. It is demonstrated that the proposed approach inherits the properties of the methods on which it is based while presents some particular advantages as well. The strategy of imposing conditions on the inlet velocity field through turbulence synthesis is implemented in the parallel multiphysics code called PETSc-FEM (http://www.cimec.org.ar/petscfem) primarily targeted to calculations throughout finite elements on general unstructured 2D and 3D grids. We present several numerical tests in order to validate and evaluate the method describing the dynamic phenomena that take place in “real-life” problems, such as a swirling turbulent flow inside a diffuser and the airflow around a vehicle model inside a wind tunnel at high Reynolds number.

  18. In-die photomask registration and overlay metrology with PROVE using 2D correlation methods

    Science.gov (United States)

    Seidel, D.; Arnz, M.; Beyer, D.

    2011-11-01

    According to the ITRS roadmap, semiconductor industry drives the 193nm lithography to its limits, using techniques like double exposure, double patterning, mask-source optimization and inverse lithography. For photomask metrology this translates to full in-die measurement capability for registration and critical dimension together with challenging specifications for repeatability and accuracy. Especially, overlay becomes more and more critical and must be ensured on every die. For this, Carl Zeiss SMS has developed the next generation photomask registration and overlay metrology tool PROVE® which serves the 32nm node and below and which is already well established in the market. PROVE® features highly stable hardware components for the stage and environmental control. To ensure in-die measurement capability, sophisticated image analysis methods based on 2D correlations have been developed. In this paper we demonstrate the in-die capability of PROVE® and present corresponding measurement results for shortterm and long-term measurements as well as the attainable accuracy for feature sizes down to 85nm using different illumination modes and mask types. Standard measurement methods based on threshold criteria are compared with the new 2D correlation methods to demonstrate the performance gain of the latter. In addition, mask-to-mask overlay results of typical box-in-frame structures down to 200nm feature size are presented. It is shown, that from overlay measurements a reproducibility budget can be derived that takes into account stage, image analysis and global effects like mask loading and environmental control. The parts of the budget are quantified from measurement results to identify critical error contributions and to focus on the corresponding improvement strategies.

  19. Power Series Approximation for the Correlation Kernel Leading to Kohn-Sham Methods Combining Accuracy, Computational Efficiency, and General Applicability

    Science.gov (United States)

    Erhard, Jannis; Bleiziffer, Patrick; Görling, Andreas

    2016-09-01

    A power series approximation for the correlation kernel of time-dependent density-functional theory is presented. Using this approximation in the adiabatic-connection fluctuation-dissipation (ACFD) theorem leads to a new family of Kohn-Sham methods. The new methods yield reaction energies and barriers of unprecedented accuracy and enable a treatment of static (strong) correlation with an accuracy of high-level multireference configuration interaction methods but are single-reference methods allowing for a black-box-like handling of static correlation. The new methods exhibit a better scaling of the computational effort with the system size than rivaling wave-function-based electronic structure methods. Moreover, the new methods do not suffer from the problem of singularities in response functions plaguing previous ACFD methods and therefore are applicable to any type of electronic system.

  20. Two-dimensional cell tracking by FPGA-optical correlation method

    Science.gov (United States)

    Solís, Iraís; Torres-Cisneros, M.; Aviña-Cervantes, J. G.; Ibarra-Manzano, O. G.; Debeir, O.; Ledesma-Orozco, S.; Pérez-Careta, E.; Sanchez-Mondragón, J. J.

    2009-06-01

    Our work uses 1080 images sequence obtained from "in vitro" samples taken every 4 min from a microscope under phase contrast technique. These images are in JPEG format and are 500×700 pixels size with a compression rate of 3:1. We developed an algorithm and characterize it over several image operations against the tracking effectiveness and its robustness respect mitosis and cell shape change. Image equalization, dilation and erosion were the image processing procedures founded to provide best tracking results. Equalization procedure, for example, required a time delay of 5 sec for a size target of 60×90 pixels and 9 sec for size target of 89×100 pixels. This algorithm was implemented into a FPGA which controlled our optical correlator in order to performance all Fourier operations by optical method. Our results showed that the use of the optical correlator can reduce the time consuming in the image process until for 90% which able us to track cells in vascular structure.

  1. Exploiting Attribute Correlations: A Novel Trace Lasso-Based Weakly Supervised Dictionary Learning Method.

    Science.gov (United States)

    Wu, Lin; Wang, Yang; Pan, Shirui

    2016-10-04

    It is now well established that sparse representation models are working effectively for many visual recognition tasks, and have pushed forward the success of dictionary learning therein. Recent studies over dictionary learning focus on learning discriminative atoms instead of purely reconstructive ones. However, the existence of intraclass diversities (i.e., data objects within the same category but exhibit large visual dissimilarities), and interclass similarities (i.e., data objects from distinct classes but share much visual similarities), makes it challenging to learn effective recognition models. To this end, a large number of labeled data objects are required to learn models which can effectively characterize these subtle differences. However, labeled data objects are always limited to access, committing it difficult to learn a monolithic dictionary that can be discriminative enough. To address the above limitations, in this paper, we propose a weakly-supervised dictionary learning method to automatically learn a discriminative dictionary by fully exploiting visual attribute correlations rather than label priors. In particular, the intrinsic attribute correlations are deployed as a critical cue to guide the process of object categorization, and then a set of subdictionaries are jointly learned with respect to each category. The resulting dictionary is highly discriminative and leads to intraclass diversity aware sparse representations. Extensive experiments on image classification and object recognition are conducted to show the effectiveness of our approach.

  2. Searching non-impulsive earthquakes using a full-waveform, cross-correlation detection method.

    Science.gov (United States)

    alinne solano, ericka; Hjorleifsdottir, Vala

    2016-04-01

    Some seismic events, which have low P-wave amplitude, pass undetected by regional or global networks. A subset of these events occur due to fast mass movement as in the case of rapid glacial movements (Ekström, et al., 2003; Ekström, et al., 2006) or landslides (Ekstrom and Stark, 2013). Some other events depleted in high frequencies are related to volcanic activity (e.g. Schuler and Ekstrom, 2009) or to non-volcanic tremors (Obara, 2002). Furthermore, non-impulsive earthquakes have been located on oceanic transform faults (OTF) (Abercrombie and Ekstrom, 2001). A suite of methods can be used to detect these non-impulsive events. Correlation, matched filter, or template event methods (e.g. Schaff and Waldhauser 2010; Rubinstein & Beroza 2007) are very efficient for detecting smaller events occurring in a similar place and with the same mechanism as a larger template event. One such method (Ekström, 2006), that is applied on the scale of the globe, routinely detects events with magnitudes around Mw 5 and larger. In this work we want to lower the detection threshold by using shorter period records registered by regional networks together with a full-waveform detection method based on time reversal schemes (Solano, et al., in prep.). The method uses continuous observed seismograms, together with moment tensor responses calculated for a 3D structure. Looking for events on the East Pacific Rise (EPR) around 9 N in one month of data from the National Seismological broadband Network (Servicio Sismologico Nacional, SSN), we found one new event. However, we also had 435 false detections due to high noise levels at several stations, gaps in the data or detection of teleseismic phases. To manually discard these events is a time consuming task that should be automated. We are working on several strategies, including weighting the input traces by their signal to noise ratio, correlation of a template peak associated to the detection function and the coincidence in time of the

  3. Correlation energies by the generator coordinate method: computational aspects for quadrupolar deformations

    CERN Document Server

    Bender, M; Heenen, P H

    2004-01-01

    We investigate truncation schemes to reduce the computational cost of calculating correlations by the generator coordinate method based on mean-field wave functions. As our test nuclei, we take examples for which accurate calculations are available. These include a strongly deformed nucleus, 156Sm, a nucleus with strong pairing, 120Sn, the krypton isotope chain which contains examples of soft deformations, and the lead isotope chain which includes the doubly magic 208Pb. We find that the Gaussian overlap approximation for angular momentum projection is effective and reduces the computational cost by an order of magnitude. Cost savings in the deformation degrees of freedom are harder to realize. A straightforward Gaussian overlap approximation can be applied rather reliably to angular-momentum projected states based on configuration sets having the same sign deformation (prolate or oblate), but matrix elements between prolate and oblate deformations must be treated with more care. We propose a two-dimensional ...

  4. Method of encouraging attention by correlating video game difficulty with attention level

    Science.gov (United States)

    Pope, Alan T. (Inventor); Bogart, Edward H. (Inventor)

    1994-01-01

    A method of encouraging attention in persons such as those suffering from Attention Deficit Disorder is provided by correlating the level of difficulty of a video game with the level of attention in a subject. A conventional video game comprises a video display which depicts objects for interaction with a player and a difficulty adjuster which increases the difficulty level, e.g., action speed and/or evasiveness of the depicted object, in a predetermined manner. The electrical activity of the brain is measured at selected sites to determine levels of awareness, e.g., activity in the beta, theta, and alpha states. A value is generated based on this measured electrical signal which is indicative of the level of awareness. The difficulty level of the game is increased as the awareness level value decreases and is decreased as this awareness level value increases.

  5. Corner-Space Renormalization Method for Driven-Dissipative Two-Dimensional Correlated Systems.

    Science.gov (United States)

    Finazzi, S; Le Boité, A; Storme, F; Baksic, A; Ciuti, C

    2015-08-21

    We present a theoretical method to study driven-dissipative correlated quantum systems on lattices with two spatial dimensions (2D). The steady-state density matrix of the lattice is obtained by solving the master equation in a corner of the Hilbert space. The states spanning the corner space are determined through an iterative procedure, using eigenvectors of the density matrix of smaller lattice systems, merging in real space two lattices at each iteration and selecting M pairs of states by maximizing their joint probability. The accuracy of the results is then improved by increasing the dimension M of the corner space until convergence is reached. We demonstrate the efficiency of such an approach by applying it to the driven-dissipative 2D Bose-Hubbard model, describing lattices of coupled cavities with quantum optical nonlinearities.

  6. Scaled Opposite Spin Second Order Moller-Plesset Correlation Energy: An Economical Electronic Structure Method

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Yousung; Lochan, Rohini C.; Dutoi, Anthony D.; Head-Gordon, Martin

    2004-08-02

    A simplified approach to treating the electron correlation energy is suggested in which only the alpha-beta component of the second order Moller-Plesset energy is evaluated, and then scaled by an empirical factor which is suggested to be 1.3. This scaled opposite spin second order energy (SOS-MP2) yields results for relative energies and derivative properties that are statistically improved over the conventional MP2 method. Furthermore, the SOS-MP2 energy can be evaluated without the 5th order computational steps associated with MP2 theory, even without exploiting any spatial locality. A 4th order algorithm is given for evaluating the opposite spin MP2 energy using auxiliary basis expansions, and a Laplace approach, and timing comparisons are given.

  7. A Design Method of Code Correlation Reference Waveform in GNSS Based on Least-Squares Fitting.

    Science.gov (United States)

    Xu, Chengtao; Liu, Zhe; Tang, Xiaomei; Wang, Feixue

    2016-07-29

    The multipath effect is one of the main error sources in the Global Satellite Navigation Systems (GNSSs). The code correlation reference waveform (CCRW) technique is an effective multipath mitigation algorithm for the binary phase shift keying (BPSK) signal. However, it encounters the false lock problem in code tracking, when applied to the binary offset carrier (BOC) signals. A least-squares approximation method of the CCRW design scheme is proposed, utilizing the truncated singular value decomposition method. This algorithm was performed for the BPSK signal, BOC(1,1) signal, BOC(2,1) signal, BOC(6,1) and BOC(7,1) signal. The approximation results of CCRWs were presented. Furthermore, the performances of the approximation results are analyzed in terms of the multipath error envelope and the tracking jitter. The results show that the proposed method can realize coherent and non-coherent CCRW discriminators without false lock points. Generally, there is performance degradation in the tracking jitter, if compared to the CCRW discriminator. However, the performance promotions in the multipath error envelope for the BOC(1,1) and BPSK signals makes the discriminator attractive, and it can be applied to high-order BOC signals.

  8. Comparison of phase recovery methods in spiral speckle pattern interferometry correlation fringes

    Science.gov (United States)

    Vadnjal, Ana Laura; Etchepareborda, Pablo; Bianchetti, Arturo; Veiras, Francisco E.; Federico, Alejandro; Kaufmann, Guillermo H.

    2016-05-01

    Spiral interferometry can be used as a solution to the problem of sign ambiguity presented in the conventional speckle pattern interferometric technique when the optical phase needs to be reconstructed from a single closed fringe system. Depressions and elevations of the topography corresponding to the object deformation are distinguished by the direction of rotation of the local spiral fringe pattern. In this work, we implement and compare several methods for optical phase reconstruction by analyzing a single image composed of spiral speckle pattern interferometry correlation fringes. The implemented methods are based on contour line demodulation, center line demodulation, Spiral Phase Quadrature Transform and the 2D Riesz transform with multivector structure. Contour line and center line demodulation approaches are exclusively dedicated to images containing a fringe system with spiral structure. The others are based on the 2D Riesz transform, these being well known approaches in conventional interferometry. We examine simulated experiments and analyze some of the emerging drawbacks for solving the phase reconstruction problem by using different mean values of speckle size and background noise levels. We also discuss several numerical procedures that may well improve the efficiency and robustness of the presented numerical implementations. The performance of the implemented demodulation methods is evaluated by using a universal image quality index and therefore a quantitative comparison is also presented.

  9. A high throughput and sensitive method correlates neuronal disorder genotypes to Drosophila larvae crawling phenotypes.

    Science.gov (United States)

    Jakubowski, Brandon R; Longoria, Rafael A; Shubeita, George T

    2012-01-01

    Drosophila melanogaster is widely used as a model system for development and disease. Due to the homology between Drosophila and human genes, as well as the tractable genetics of the fly, its use as a model for neurologic disorders, in particular, has been rising. Locomotive impairment is a commonly used diagnostic for screening and characterization of these models, yet a fast, sensitive and model-free method to compare behavior is lacking. Here, we present a high throughput method to quantify the crawling behavior of larvae. We use the mean squared displacement as well as the direction autocorrelation of the crawling larvae as descriptors of their motion. By tracking larvae from wild-type strains and models of the Fragile X mental retardation as well as Alzheimer disease, we show these mutants exhibit impaired crawling. We further show that the magnitude of impairment correlates with the severity of the mutation, demonstrating the sensitivity and the dynamic range of the method. Finally, we study larvae with altered expression of the shaggy gene, a homolog of Glycogen Synthase Kinase-3 (GSK-3), which has been implicated in Alzheimer disease. Surprisingly, we find that both increased and decreased expression of dGSK-3 lead to similar larval crawling impairment. These findings have implications for the use of GSK-3 inhibitors recently proposed for Alzheimer treatment.

  10. Correlated Random Systems Five Different Methods : CIRM Jean-Morlet Chair

    CERN Document Server

    Kistler, Nicola

    2015-01-01

    This volume presents five different methods recently developed to tackle the large scale behavior of highly correlated random systems, such as spin glasses, random polymers, local times and loop soups and random matrices. These methods, presented in a series of lectures delivered within the Jean-Morlet initiative (Spring 2013), play a fundamental role in the current development of probability theory and statistical mechanics. The lectures were: Random Polymers by E. Bolthausen, Spontaneous Replica Symmetry Breaking and Interpolation Methods by F. Guerra, Derrida's Random Energy Models by N. Kistler, Isomorphism Theorems by J. Rosen and Spectral Properties of Wigner Matrices by B. Schlein. This book is the first in a co-edition between the Jean-Morlet Chair at CIRM and the Springer Lecture Notes in Mathematics which aims to collect together courses and lectures on cutting-edge subjects given during the term of the Jean-Morlet Chair, as well as new material produced in its wake. It is targeted at researchers, i...

  11. Advanced digital speckle correlation method for strain measurement and nondestructive testing

    Science.gov (United States)

    Jin, Guan-chang; Bao, Nai-Keng; Chung, Po Sheun

    1997-03-01

    An advanced digital speckle correlation method (DSCM) is presented in this paper. The advantages of this method will not only improve the processing speed but also increase the measuring accuracy. Some mathematics tools are derived and a powerful computing program is developed for further applications. A new feature of the measuring sensitivity of DSCM that can be varied by different amplification of the optical arrangement is first presented. This advantage may be superior to those available in other optical metrology methods like Electronic Speckle Pattern Interferometry (ESPI) in micro-deformation measurements. The applications of strain measurement and nondestructive testing are described and the advantages of DSCM are obvious. Some examples of material behavior measurement and plastic strain measurement are presented. Due to the high sensitivity of DSCM, another potential application in nondestructive testing (NDT) is also described in this paper. From the application examples given, this advanced DSCM proves to be a new and effective optical strain sensing technique especially for small objects or micro-deformation measurements.

  12. A Group Contribution Method for the Correlation of Static Dielectric Constant of Ionic Liquids

    Institute of Scientific and Technical Information of China (English)

    周颖; 林真; 吴可君; 徐国华; 何潮洪

    2014-01-01

    Static dielectric constant is a key parameter to estimate the electro-viscous effect which plays important roles in the flow and convective heat transfer of fluids with ions in microfluidic devices such as micro reactors and heat exchangers. A group contribution method based on 27 groups is developed for the correlation of static dielec-tric constant of ionic liquids in this paper. The ionic liquids considered include imidazolium, pyridinium, pyrrolid-inium, alkylammonium, alkylsulfonium, morpholinium and piperidinium cations and various anions. The data col-lected cover the temperature ranges of 278.15-343.15 K and static dielectric constant ranges of 9.4-85.6. The re-sults of the method show a satisfactory agreement with the literature data with an average absolute relative devia-tion of 7.41%, which is generally of the same order of the experimental data accuracy. The method proposed in this paper provides a simple but reliable approach for the prediction of static dielectric constant of ionic liquids at dif-ferent temperatures.

  13. Augmented laminography, a correlative 3D imaging method for revealing the inner structure of compressed fossils

    Science.gov (United States)

    Zuber, Marcus; Laaß, Michael; Hamann, Elias; Kretschmer, Sophie; Hauschke, Norbert; van de Kamp, Thomas; Baumbach, Tilo; Koenig, Thomas

    2017-01-01

    Non-destructive imaging techniques can be extremely useful tools for the investigation and the assessment of palaeontological objects, as mechanical preparation of rare and valuable fossils is precluded in most cases. However, palaeontologists are often faced with the problem of choosing a method among a wide range of available techniques. In this case study, we employ x-ray computed tomography (CT) and computed laminography (CL) to study the first fossil xiphosuran from the Muschelkalk (Middle Triassic) of the Netherlands. The fossil is embedded in micritic limestone, with the taxonomically important dorsal shield invisible, and only the outline of its ventral part traceable. We demonstrate the complementarity of CT and CL which offers an excellent option to visualize characteristic diagnostic features. We introduce augmented laminography to correlate complementary information of the two methods in Fourier space, allowing to combine their advantages and finally providing increased anatomical information about the fossil. This method of augmented laminography enabled us to identify the xiphosuran as a representative of the genus Limulitella. PMID:28128302

  14. A Design Method of Code Correlation Reference Waveform in GNSS Based on Least-Squares Fitting

    Science.gov (United States)

    Xu, Chengtao; Liu, Zhe; Tang, Xiaomei; Wang, Feixue

    2016-01-01

    The multipath effect is one of the main error sources in the Global Satellite Navigation Systems (GNSSs). The code correlation reference waveform (CCRW) technique is an effective multipath mitigation algorithm for the binary phase shift keying (BPSK) signal. However, it encounters the false lock problem in code tracking, when applied to the binary offset carrier (BOC) signals. A least-squares approximation method of the CCRW design scheme is proposed, utilizing the truncated singular value decomposition method. This algorithm was performed for the BPSK signal, BOC(1,1) signal, BOC(2,1) signal, BOC(6,1) and BOC(7,1) signal. The approximation results of CCRWs were presented. Furthermore, the performances of the approximation results are analyzed in terms of the multipath error envelope and the tracking jitter. The results show that the proposed method can realize coherent and non-coherent CCRW discriminators without false lock points. Generally, there is performance degradation in the tracking jitter, if compared to the CCRW discriminator. However, the performance promotions in the multipath error envelope for the BOC(1,1) and BPSK signals makes the discriminator attractive, and it can be applied to high-order BOC signals. PMID:27483275

  15. Method of Removing the Cross-correlation Noise for Dual-input and Dual-output SAR

    Directory of Open Access Journals (Sweden)

    Huang Ping-ping

    2012-03-01

    Full Text Available According to analysis of separating the mixed echo by suppressing the cross-correlation noise in dual-input and dual-output SAR system, a new method based on threshold filter and inverse filter was proposed. The method can eliminate the most energy of cross-correlation noise by threshold filter, which can suppress the cross-correlation noise well. The principle and implementation steps are presented in detail. The computer simulation and account for the integrated sidelobe ratio showed the effectiveness of the proposed method.

  16. Calculation of correlated initial state in the hierarchical equations of motion method using an imaginary time path integral approach.

    Science.gov (United States)

    Song, Linze; Shi, Qiang

    2015-11-21

    Based on recent findings in the hierarchical equations of motion (HEOM) for correlated initial state [Y. Tanimura, J. Chem. Phys. 141, 044114 (2014)], we propose a new stochastic method to obtain the initial conditions for the real time HEOM propagation, which can be used further to calculate the equilibrium correlation functions and symmetrized correlation functions. The new method is derived through stochastic unraveling of the imaginary time influence functional, where a set of stochastic imaginary time HEOM are obtained. The validity of the new method is demonstrated using numerical examples including the spin-Boson model, and the Holstein model with undamped harmonic oscillator modes.

  17. Correlation of different phenotypic drug susceptibility testing methods for four fluoroquinolones in Mycobacterium tuberculosis.

    Science.gov (United States)

    Coeck, Nele; de Jong, Bouke C; Diels, Maren; de Rijk, Pim; Ardizzoni, Elisa; Van Deun, Armand; Rigouts, Leen

    2016-05-01

    Molecular resistance testing fails to explain all fluoroquinolone resistance, with a continued need for a suitable rapid phenotypic drug susceptibility testing method. To evaluate the optimal method for phenotypic fluoroquinolone susceptibility testing. Using Löwenstein-Jensen medium, Middlebrook 7H11 agar, BACTEC-MGIT 960 and the resazurin microtitre plate assay, we determined susceptibility to fluoroquinolones in Mycobacterium tuberculosis and investigated cross-resistance between ofloxacin, levofloxacin, moxifloxacin and gatifloxacin. We compared MICs of all four fluoroquinolones for 91 strains on Löwenstein-Jensen (as the gold standard) with their MICs in resazurin plates, and with ofloxacin susceptibility at a single concentration in MGIT and on 7H11 agar, in addition to sequencing of the gyrAB genes. Applying a cut-off of 2 mg/L ofloxacin, 1 mg/L levofloxacin and 0.5 mg/L moxifloxacin and gatifloxacin in all methods, some discordance between solid medium and MGIT methods was observed, yet this tended to be explained by MICs around the cut-off. The high discordance between Löwenstein-Jensen (LJ) and resazurin plates suggests that the currently applied cut-offs for all fluoroquinolones in the resazurin method should decrease and minor changes in colour (from blue to purple) be considered as meaningful. High-level resistance in all assays to all drugs correlated well with the presence of gyrA mutations, in support of recent findings that fluoroquinolone resistance should be tested at different concentrations, as patients with lower levels of resistance may continue to benefit from high-dose fluoroquinolone-based therapy. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.

  18. Pore Network Modeling: Alternative Methods to Account for Trapping and Spatial Correlation

    KAUST Repository

    De La Garza Martinez, Pablo

    2016-05-01

    Pore network models have served as a predictive tool for soil and rock properties with a broad range of applications, particularly in oil recovery, geothermal energy from underground reservoirs, and pollutant transport in soils and aquifers [39]. They rely on the representation of the void space within porous materials as a network of interconnected pores with idealised geometries. Typically, a two-phase flow simulation of a drainage (or imbibition) process is employed, and by averaging the physical properties at the pore scale, macroscopic parameters such as capillary pressure and relative permeability can be estimated. One of the most demanding tasks in these models is to include the possibility of fluids to remain trapped inside the pore space. In this work I proposed a trapping rule which uses the information of neighboring pores instead of a search algorithm. This approximation reduces the simulation time significantly and does not perturb the accuracy of results. Additionally, I included spatial correlation to generate the pore sizes using a matrix decomposition method. Results show higher relative permeabilities and smaller values for irreducible saturation, which emphasizes the effects of ignoring the intrinsic correlation seen in pore sizes from actual porous media. Finally, I implemented the algorithm from Raoof et al. (2010) [38] to generate the topology of a Fontainebleau sandstone by solving an optimization problem using the steepest descent algorithm with a stochastic approximation for the gradient. A drainage simulation is performed on this representative network and relative permeability is compared with published results. The limitations of this algorithm are discussed and other methods are suggested to create a more faithful representation of the pore space.

  19. A refined method for calculating paleotemperatures from linear correlations in bamboo coral carbon and oxygen isotopes

    Science.gov (United States)

    Saenger, Casey; Watkins, James M.

    2016-06-01

    Bamboo corals represent an emerging paleoclimate archive with the potential to record variability at intermediate depths throughout much of the global ocean. Realizing this potential has been complicated by biologically mediated vital effects, which are evident in linear correlations of skeletal carbon (δ13C) and oxygen (δ18O) isotope composition. Previous efforts to develop a bamboo coral δ18O paleothermometer by accounting for such vital effects have not been completely successful as they still rely on empirical calibrations that are offset from the temperature dependence of abiogenic experiments. Here we describe an approach that better corrects for bamboo coral vital effects and allows paleotemperatures to be calculated directly from the abiogenic temperature dependence. The success of the method lies in calculating apparent equilibrium carbon and oxygen isotope fractionation at the temperature, pH, and growth rate of each coral, as well as in the use of model II regressions. Rigorous propagation of uncertainty suggests typical errors of ±2-3°C, but in select cases errors as low as ±0.65°C can be achieved for densely sampled and strongly correlated data sets. This lower limit approaches the value attributed to uncertainty in pH and growth rate estimates alone, as predicted by a series of pseudoproxy experiments. The incorporation of isotopically light metabolic CO2 appears to be negligible in most Pacific corals, but may be significant in Atlantic specimens, potentially requiring an additional correction. The success of the method therefore hinges on how well complex environmental systems and biomineralization strategies are constrained, with the most reliable temperatures occurring when calcifying fluid pH, growth rate, and incorporation of metabolic carbon into skeletal calcite are constrained using multiple geochemical proxies.

  20. Correlations between two different methods to score bleeding and the relationship with plaque in systemically healthy young adults

    NARCIS (Netherlands)

    Cioccari Oliveira, S.; Slot, D.E.; Celeste, R.K.; Abegg, C.; Keijser, B.J.F.; van der Weijden, F.A.

    2015-01-01

    Aim To evaluate the correlation between bleeding on marginal probing (BOMP) and bleeding on pocket probing (BOPP), and the correlation of both bleeding indices with plaque. Materials and Methods This cross-sectional study screened 336 participants, from which 268 were eligible for examination and

  1. Application of Corner Transfer Matrix Renormalization Group Method to the Correlation Function of a Two-Dimensional Ising Model

    Institute of Scientific and Technical Information of China (English)

    何春山; 李志兵

    2003-01-01

    The correlation function of a two-dimensionalIsing model is calculated by the corner transfer matrix renormalization group method.We obtain the critical exponent η= 0.2496 with few computer resources.

  2. The Correlation Function of Multiple Dependent Poisson Processes Generated by the Alternating Renewal Process Method

    CERN Document Server

    Johnson, Don H

    2008-01-01

    We derive conditions under which alternating renewal processes can be used to construct correlated Poisson processes. The pairwise correlation function is also derived, showing that the resulting correlations can be negative. The technique and the analysis can be extended to the generation of two or more dependent renewal processes.

  3. Development of method for evaluating cell hardness and correlation between bacterial spore hardness and durability

    Directory of Open Access Journals (Sweden)

    Nakanishi Koichi

    2012-06-01

    Full Text Available Abstract Background Despite the availability of conventional devices for making single-cell manipulations, determining the hardness of a single cell remains difficult. Here, we consider the cell to be a linear elastic body and apply Young’s modulus (modulus of elasticity, which is defined as the ratio of the repulsive force (stress in response to the applied strain. In this new method, a scanning probe microscope (SPM is operated with a cantilever in the “contact-and-push” mode, and the cantilever is applied to the cell surface over a set distance (applied strain. Results We determined the hardness of the following bacterial cells: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and five Bacillus spp. In log phase, these strains had a similar Young’s modulus, but Bacillus spp. spores were significantly harder than the corresponding vegetative cells. There was a positive, linear correlation between the hardness of bacterial spores and heat or ultraviolet (UV resistance. Conclusions Using this technique, the hardness of a single vegetative bacterial cell or spore could be determined based on Young’s modulus. As an application of this technique, we demonstrated that the hardness of individual bacterial spores was directly proportional to heat and UV resistance, which are the conventional measures of physical durability. This technique allows the rapid and direct determination of spore durability and provides a valuable and innovative method for the evaluation of physical properties in the field of microbiology.

  4. Two-point estimate method for probabilistic optimal power flow computation including wind farms with correlated parameters

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xue; Cao, Jia; Du, Dajun [Shanghai Univ. (China). Key Lab. of Power Station Automation Technology

    2013-07-01

    This paper is concerned with the probabilistic optimal power flow (POPF) calculation including wind farms with correlated parameters which contains nodal injections. The two-point estimate method (2PEM) is employed to solve the POPF. Moreover, the correlation samples between nodal injections and line parameters are generated by Cholesky Factorization method. Simulation results show that 2PEM is feasible and effective to solve the POPF including wind farms with correlated parameters, while the 2PEM has higher computation precision and consume less CPU time than Monte Carlo Simulation.

  5. The application of the multifractal cross-correlation analysis methods in radar target detection within sea clutter

    Science.gov (United States)

    Xi, Caiping; Zhang, Shuning; Xiong, Gang; Zhao, Huichang; Yang, Yonghong

    2017-02-01

    Many complex systems generate multifractal time series which are long-range cross-correlated. This paper introduces three multifractal cross-correlation analysis methods, such as multifractal cross-correlation analysis based on the partition function approach (MFXPF), multifractal detrended cross-correlation analysis (MFDCCA) methods based on detrended fluctuation analysis (MFXDFA) and detrended moving average analysis (MFXDMA), which only consider one moment order. We do comparative analysis of the artificial time series (binomial multiplicative cascades and Cantor sets with different probabilities) by these methods. Then we do a feasibility test of the fixed threshold target detection within sea clutter by applying the multifractal cross-correlation analysis methods to the IPIX radar sea clutter data. The results show that it is feasible to use the method of the fixed threshold based on the multifractal feature parameter Δf(α) by the MFXPF and MFXDFA-1 methods. At last, we give the main conclusions and provide a valuable reference on how to choose the multifractal algorithms, the detection parameters and the target detection methods within sea clutter in practice.

  6. Pharmacokinetic-pharmacodynamic correlation of imipenem in pediatric burn patients using a bioanalytical liquid chromatographic method

    Directory of Open Access Journals (Sweden)

    Silvia Regina Cavani Jorge Santos

    2015-06-01

    Full Text Available A bioanalytical method was developed and applied to quantify the free imipenem concentrations for pharmacokinetics and PK/PD correlation studies of the dose adjustments required to maintain antimicrobial effectiveness in pediatric burn patients. A reverse-phase Supelcosil LC18 column (250 x 4.6 mm 5 micra, binary mobile phase consisting of 0.01 M, pH 7.0 phosphate buffer and acetonitrile (99:1, v/v, flow rate of 0.8 mL/min, was applied. The method showed good absolute recovery (above 90%, good linearity (0.25-100.0 µg/mL, r2=0.999, good sensitivity (LLOQ: 0.25 µg/mL; LLOD: 0.12 µg/mL and acceptable stability. Inter/intraday precision values were 7.3/5.9%, and mean accuracy was 92.9%. A bioanalytical method was applied to quantify free drug concentrations in children with burns. Six pediatric burn patients (median 7.0 years old, 27.5 kg, normal renal function, and 33% total burn surface area were prospectively investigated; inhalation injuries were present in 4/6 (67% of the patients. Plasma monitoring and PK assessments were performed using a serial blood sample collection for each set, totaling 10 sets. The PK/PD target attained (40%T>MIC for each minimum inhibitory concentration (MIC: 0.5, 1.0, 2.0, 4.0 mg/L occurred at a percentage higher than 80% of the sets investigated and 100% after dose adjustment. In conclusion, the purification of plasma samples using an ultrafiltration technique followed by quantification of imipenem plasma measurements using the LC method is quite simple, useful, and requires small volumes for blood sampling. In addition, a small amount of plasma (0.25 mL is needed to guarantee drug effectiveness in pediatric burn patients. There is also a low risk of neurotoxicity, which is important because pharmacokinetics are unpredictable in these critical patients with severe hospital infection. Finally, the PK/PD target was attained for imipenem in the control of sepsis in pediatric patients with burns.

  7. Correlation between vacancies and magnetoresistance changes in FM manganites using the Monte Carlo method

    Science.gov (United States)

    Agudelo-Giraldo, J. D.; Restrepo-Parra, E.; Restrepo, J.

    2015-10-01

    The Metropolis algorithm and the classical Heisenberg approximation were implemented by the Monte Carlo method to design a computational approach to the magnetization and resistivity of La2/3Ca1/3MnO3, which depends on the Mn ion vacancies as the external magnetic field increases. This compound is ferromagnetic, and it exhibits the colossal magnetoresistance (CMR) effect. The monolayer was built with L×L×d dimensions, and it had L=30 umc (units of magnetic cells) for its dimension in the x-y plane and was d=12 umc in thickness. The Hamiltonian that was used contains interactions between first neighbors, the magnetocrystalline anisotropy effect and the external applied magnetic field response. The system that was considered contains mixed-valence bonds: Mn3+eg'-O-Mn3+eg, Mn3+eg-O-Mn4+d3 and Mn3+eg'-O-Mn4+d3. The vacancies were placed randomly in the sample, replacing any type of Mn ion. The main result shows that without vacancies, the transitions TC (Curie temperature) and TMI (metal-insulator temperature) are similar, whereas with the increase in the vacancy percentage, TMI presented lower values than TC. This situation is caused by the competition between the external magnetic field, the vacancy percentage and the magnetocrystalline anisotropy, which favors the magnetoresistive effect at temperatures below TMI. Resistivity loops were also observed, which shows a direct correlation with the hysteresis loops of magnetization at temperatures below TC.

  8. Investigation of Rock Failure Pattern in Creep by Digital Speckle Correlation Method

    Directory of Open Access Journals (Sweden)

    Yunliang Tan

    2013-01-01

    Full Text Available In order to study the mechanical characteristics from creep deformation to failure of rock, the tests of uniaxial compression and pushing steel-plate anchored in rock were performed, by using RLJW-2000 servo test synchronizing with Digital Speckle Correlation Method (DSCM. The investigations showed that for a uniaxial compressive specimen, when load arrived at 0.5σc, displacement clusters orderly formed, which was ahead of the macrocreep strain occurring in a slight jump mode when load arrived at 0.7σc. When the load level arrived at 0.8σc, displacement clusters gathered to be a narrow band. After that, the specimen abruptly fractured in a shear mode. In the creep pushing steel-plate test, when pushing force arrived at 25 kN, crack began to occur, the horizontal displacement field as well as shear strain field concentrated continuously along the interface between steel-plate and rock, and a new narrow concentrating band gathered in the upper layer. When pushing force arrived at 27.5 kN, another new narrow shear deformation band formed in the lower layer. Then, the steel-plate was pushed out quickly accompanying strong creep deformation.

  9. Predicting residue contacts using pragmatic correlated mutations method: reducing the false positives

    Directory of Open Access Journals (Sweden)

    Alexov Emil G

    2006-11-01

    Full Text Available Abstract Background Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the predicted 3D structures. The correlated mutations (CM method serves as the most promising approach and it has been used to predict amino acids pairs that are distant in the primary sequence but form contacts in the native 3D structure of homologous proteins. Results Here we report a new implementation of the CM method with an added set of selection rules (filters. The parameters of the algorithm were optimized against fifteen high resolution crystal structures with optimization criterion that maximized the confidentiality of the predictions. The optimization resulted in a true positive ratio (TPR of 0.08 for the CM without filters and a TPR of 0.14 for the CM with filters. The protocol was further benchmarked against 65 high resolution structures that were not included in the optimization test. The benchmarking resulted in a TPR of 0.07 for the CM without filters and to a TPR of 0.09 for the CM with filters. Conclusion Thus, the inclusion of selection rules resulted to an overall improvement of 30%. In addition, the pair-wise comparison of TPR for each protein without and with filters resulted in an average improvement of 1.7. The methodology was implemented into a web server http://www.ces.clemson.edu/compbio/recon that is freely available to the public. The purpose of this implementation is to provide the 3D structure predictors with a tool that can help with ranking alternative models by satisfying the largest number of predicted contacts, as well as it can provide a confidence score for contacts in cases where structure is known.

  10. A new method for improving functional-to-structural MRI alignment using local Pearson correlation.

    Science.gov (United States)

    Saad, Ziad S; Glen, Daniel R; Chen, Gang; Beauchamp, Michael S; Desai, Rutvik; Cox, Robert W

    2009-02-01

    Accurate registration of Functional Magnetic Resonance Imaging (FMRI) T2-weighted volumes to same-subject high-resolution T1-weighted structural volumes is important for Blood Oxygenation Level Dependent (BOLD) FMRI and crucial for applications such as cortical surface-based analyses and pre-surgical planning. Such registration is generally implemented by minimizing a cost functional, which measures the mismatch between two image volumes over the group of proper affine transformations. Widely used cost functionals, such as mutual information (MI) and correlation ratio (CR), appear to yield decent alignments when visually judged by matching outer brain contours. However, close inspection reveals that internal brain structures are often significantly misaligned. Poor registration is most evident in the ventricles and sulcal folds, where CSF is concentrated. This observation motivated our development of an improved modality-specific cost functional which uses a weighted local Pearson coefficient (LPC) to align T2- and T1-weighted images. In the absence of an alignment gold standard, we used three human observers blinded to registration method to provide an independent assessment of the quality of the registration for each cost functional. We found that LPC performed significantly better (p<0.001) than generic cost functionals including MI and CR. Generic cost functionals were very often not minimal near the best alignment, thereby suggesting that optimization is not the cause of their failure. Lastly, we emphasize the importance of precise visual inspection of alignment quality and present an automated method for generating composite images that help capture errors of misalignment.

  11. Application of an improved maximum correlated kurtosis deconvolution method for fault diagnosis of rolling element bearings

    Science.gov (United States)

    Miao, Yonghao; Zhao, Ming; Lin, Jing; Lei, Yaguo

    2017-08-01

    The extraction of periodic impulses, which are the important indicators of rolling bearing faults, from vibration signals is considerably significance for fault diagnosis. Maximum correlated kurtosis deconvolution (MCKD) developed from minimum entropy deconvolution (MED) has been proven as an efficient tool for enhancing the periodic impulses in the diagnosis of rolling element bearings and gearboxes. However, challenges still exist when MCKD is applied to the bearings operating under harsh working conditions. The difficulties mainly come from the rigorous requires for the multi-input parameters and the complicated resampling process. To overcome these limitations, an improved MCKD (IMCKD) is presented in this paper. The new method estimates the iterative period by calculating the autocorrelation of the envelope signal rather than relies on the provided prior period. Moreover, the iterative period will gradually approach to the true fault period through updating the iterative period after every iterative step. Since IMCKD is unaffected by the impulse signals with the high kurtosis value, the new method selects the maximum kurtosis filtered signal as the final choice from all candidates in the assigned iterative counts. Compared with MCKD, IMCKD has three advantages. First, without considering prior period and the choice of the order of shift, IMCKD is more efficient and has higher robustness. Second, the resampling process is not necessary for IMCKD, which is greatly convenient for the subsequent frequency spectrum analysis and envelope spectrum analysis without resetting the sampling rate. Third, IMCKD has a significant performance advantage in diagnosing the bearing compound-fault which expands the application range. Finally, the effectiveness and superiority of IMCKD are validated by a number of simulated bearing fault signals and applying to compound faults and single fault diagnosis of a locomotive bearing.

  12. Radioguided breast surgery for occult lesion localization – correlation between two methods

    Directory of Open Access Journals (Sweden)

    Gutfilen Bianca

    2008-08-01

    Full Text Available Abstract Background The detection of sub-clinical breast lesions has increased with screening mammography. Biopsy techniques can offer precision and agility in its execution, as well as patient comfort. This trial compares radioguided occult lesion localization (ROLL and wire-guided localization (WL of breast lesions. We investigate if a procedure at the ambulatorial level (ROLL could lead to a better aesthetic result and less postoperative pain. In addition, we intend to demonstrate the efficacy of radioguided localization and removal of occult breast lesions using radiopharmaceuticals injected directly into the lesions and correlate radiological and histopathological findings. Methods One hundred and twenty patients were randomized into two groups (59 WL and 61 ROLL. The patients were requested to score the cosmetic appearance of their breast after surgery, and a numerical rating scale was used to measure pain on the first postoperative day. Clearance margins were considered at ≥ 10 mm for invasive cancer, ≥ 5 mm for ductal carcinoma in situ, and ≥ 1 mm for benign disease. Patients were subsequently treated according to the definitive histological result. When appropriate, different statistical tests were used in order to test the significance between the two groups, considering a P value Results WL and ROLL located all the occult breast lesions successfully. In the ROLL group, the specimen volume was smaller and there were more cases with clear margins (P Conclusion ROLL is an effective method for the excision of non-palpable breast lesions. It enables more careful planning of the cutaneous incision, leading to better aesthetic results, less postoperative symptoms, and smaller volumes of excised tissue.

  13. Quantum Monte Carlo methods and strongly correlated electrons on honeycomb structures

    Energy Technology Data Exchange (ETDEWEB)

    Lang, Thomas C.

    2010-12-16

    In this thesis we apply recently developed, as well as sophisticated quantum Monte Carlo methods to numerically investigate models of strongly correlated electron systems on honeycomb structures. The latter are of particular interest owing to their unique properties when simulating electrons on them, like the relativistic dispersion, strong quantum fluctuations and their resistance against instabilities. This work covers several projects including the advancement of the weak-coupling continuous time quantum Monte Carlo and its application to zero temperature and phonons, quantum phase transitions of valence bond solids in spin-1/2 Heisenberg systems using projector quantum Monte Carlo in the valence bond basis, and the magnetic field induced transition to a canted antiferromagnet of the Hubbard model on the honeycomb lattice. The emphasis lies on two projects investigating the phase diagram of the SU(2) and the SU(N)-symmetric Hubbard model on the hexagonal lattice. At sufficiently low temperatures, condensed-matter systems tend to develop order. An exception are quantum spin-liquids, where fluctuations prevent a transition to an ordered state down to the lowest temperatures. Previously elusive in experimentally relevant microscopic two-dimensional models, we show by means of large-scale quantum Monte Carlo simulations of the SU(2) Hubbard model on the honeycomb lattice, that a quantum spin-liquid emerges between the state described by massless Dirac fermions and an antiferromagnetically ordered Mott insulator. This unexpected quantum-disordered state is found to be a short-range resonating valence bond liquid, akin to the one proposed for high temperature superconductors. Inspired by the rich phase diagrams of SU(N) models we study the SU(N)-symmetric Hubbard Heisenberg quantum antiferromagnet on the honeycomb lattice to investigate the reliability of 1/N corrections to large-N results by means of numerically exact QMC simulations. We study the melting of phases

  14. Methane fugitive emissions quantification using the novel 'plume camera' (spatial correlation) method

    Science.gov (United States)

    Crosson, E.; Rella, C.

    2012-12-01

    Fugitive emissions of methane into the atmosphere are a major concern facing the natural gas production industry. Given that the global warming potential of methane is many times greater than that of carbon dioxide, the importance of quantifying methane emissions becomes clear. The rapidly increasing reliance on shale gas (or other unconventional sources) is only intensifying the interest in fugitive methane releases. Natural gas (which is predominantly methane) is an attractive energy source, as it emits 40% less carbon dioxide per Joule of energy generated than coal. However, if just a small percentage of the natural gas consumed is lost due to fugitive emissions during production, processing, or transport, this global warming benefit is lost (Howarth et al. 2012). It is therefore imperative, as production of natural gas increases, that the fugitive emissions of methane are quantified accurately. Traditional direct measurement techniques often involve physical access of the leak itself to quantify the emissions rate, and are generally require painstaking effort to first find the leak and then quantify the emissions rate. With over half a million natural gas producing wells in the U.S. (U.S. Energy Information Administration), not including the associated processing, storage, and transport facilities, and with each facility having hundreds or even thousands of fittings that can potentially leak, the need is clear to develop methodologies that can provide a rapid and accurate assessment of the total emissions rate on a per-well head basis. In this paper we present a novel method for emissions quantification which uses a 'plume camera' with three 'pixels' to quantify emissions using direct measurements of methane concentration in the downwind plume. By analyzing the spatial correlation between the pixels, the spatial extent of the instantaneous plume can be inferred. This information, when combined with the wind speed through the measurement plane, provides a direct

  15. Population models and simulation methods: The case of the Spearman rank correlation.

    Science.gov (United States)

    Astivia, Oscar L Olvera; Zumbo, Bruno D

    2017-01-31

    The purpose of this paper is to highlight the importance of a population model in guiding the design and interpretation of simulation studies used to investigate the Spearman rank correlation. The Spearman rank correlation has been known for over a hundred years to applied researchers and methodologists alike and is one of the most widely used non-parametric statistics. Still, certain misconceptions can be found, either explicitly or implicitly, in the published literature because a population definition for this statistic is rarely discussed within the social and behavioural sciences. By relying on copula distribution theory, a population model is presented for the Spearman rank correlation, and its properties are explored both theoretically and in a simulation study. Through the use of the Iman-Conover algorithm (which allows the user to specify the rank correlation as a population parameter), simulation studies from previously published articles are explored, and it is found that many of the conclusions purported in them regarding the nature of the Spearman correlation would change if the data-generation mechanism better matched the simulation design. More specifically, issues such as small sample bias and lack of power of the t-test and r-to-z Fisher transformation disappear when the rank correlation is calculated from data sampled where the rank correlation is the population parameter. A proof for the consistency of the sample estimate of the rank correlation is shown as well as the flexibility of the copula model to encompass results previously published in the mathematical literature.

  16. A method for stereoscopic strain analysis of the right ventricle by digital image correlation during coronary bypass surgery: short communication.

    Science.gov (United States)

    Mirow, Nikolas; Hokka, Mikko; Nagel, Horst; Irqsusi, Marc; Moosdorf, Rainer G; Kuokkala, Veli-Tapani; Vogt, Sebastian

    2015-06-01

    Perioperative cardiosurgical management of volume therapy remains one of the challenging tasks in cases of patients with severe heart disease. Early detection of congestive cardiac failure prevents subsequent low output and worse outcome. An effective method for controlling extracorporeal circulation is created by developing a non-invasive intraoperative method for right ventricular strain analysis through digital image contrast correlation.

  17. Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation

    DEFF Research Database (Denmark)

    Ottesen, Johnny T.; Mehlsen, Jesper; Olufsen, Mette

    2014-01-01

    We consider the inverse and patient specific problem of short term (seconds to minutes) heart rate regulation specified by a system of nonlinear ODEs and corresponding data. We show how a recent method termed the structural correlation method (SCM) can be used for model reduction and for obtaining...

  18. Detecting correlation changes in multivariate time series: A comparison of four non-parametric change point detection methods.

    Science.gov (United States)

    Cabrieto, Jedelyn; Tuerlinckx, Francis; Kuppens, Peter; Grassmann, Mariel; Ceulemans, Eva

    2017-06-01

    Change point detection in multivariate time series is a complex task since next to the mean, the correlation structure of the monitored variables may also alter when change occurs. DeCon was recently developed to detect such changes in mean and\\or correlation by combining a moving windows approach and robust PCA. However, in the literature, several other methods have been proposed that employ other non-parametric tools: E-divisive, Multirank, and KCP. Since these methods use different statistical approaches, two issues need to be tackled. First, applied researchers may find it hard to appraise the differences between the methods. Second, a direct comparison of the relative performance of all these methods for capturing change points signaling correlation changes is still lacking. Therefore, we present the basic principles behind DeCon, E-divisive, Multirank, and KCP and the corresponding algorithms, to make them more accessible to readers. We further compared their performance through extensive simulations using the settings of Bulteel et al. (Biological Psychology, 98 (1), 29-42, 2014) implying changes in mean and in correlation structure and those of Matteson and James (Journal of the American Statistical Association, 109 (505), 334-345, 2014) implying different numbers of (noise) variables. KCP emerged as the best method in almost all settings. However, in case of more than two noise variables, only DeCon performed adequately in detecting correlation changes.

  19. Relevant modes selection method based on Spearman correlation coefficient for laser signal denoising using empirical mode decomposition

    Science.gov (United States)

    Duan, Yabo; Song, Chengtian

    2016-10-01

    Empirical mode decomposition (EMD) is a recently proposed nonlinear and nonstationary laser signal denoising method. A noisy signal is broken down using EMD into oscillatory components that are called intrinsic mode functions (IMFs). Thresholding-based denoising and correlation-based partial reconstruction of IMFs are the two main research directions for EMD-based denoising. Similar to other decomposition-based denoising approaches, EMD-based denoising methods require a reliable threshold to determine which IMFs are noise components and which IMFs are noise-free components. In this work, we propose a new approach in which each IMF is first denoised using EMD interval thresholding (EMD-IT), and then a robust thresholding process based on Spearman correlation coefficient is used for relevant modes selection. The proposed method tackles the problem using a thresholding-based denoising approach coupled with partial reconstruction of the relevant IMFs. Other traditional denoising methods, including correlation-based EMD partial reconstruction (EMD-Correlation), discrete Fourier transform and wavelet-based methods, are investigated to provide a comparison with the proposed technique. Simulation and test results demonstrate the superior performance of the proposed method when compared with the other methods.

  20. Relevant modes selection method based on Spearman correlation coefficient for laser signal denoising using empirical mode decomposition

    Science.gov (United States)

    Duan, Yabo; Song, Chengtian

    2016-12-01

    Empirical mode decomposition (EMD) is a recently proposed nonlinear and nonstationary laser signal denoising method. A noisy signal is broken down using EMD into oscillatory components that are called intrinsic mode functions (IMFs). Thresholding-based denoising and correlation-based partial reconstruction of IMFs are the two main research directions for EMD-based denoising. Similar to other decomposition-based denoising approaches, EMD-based denoising methods require a reliable threshold to determine which IMFs are noise components and which IMFs are noise-free components. In this work, we propose a new approach in which each IMF is first denoised using EMD interval thresholding (EMD-IT), and then a robust thresholding process based on Spearman correlation coefficient is used for relevant modes selection. The proposed method tackles the problem using a thresholding-based denoising approach coupled with partial reconstruction of the relevant IMFs. Other traditional denoising methods, including correlation-based EMD partial reconstruction (EMD-Correlation), discrete Fourier transform and wavelet-based methods, are investigated to provide a comparison with the proposed technique. Simulation and test results demonstrate the superior performance of the proposed method when compared with the other methods.

  1. Prevalence and correlates of suicide ideation in patients with COPD: a mixed methods study

    Directory of Open Access Journals (Sweden)

    Fleehart S

    2014-12-01

    Full Text Available Sara Fleehart,1,* Vincent S Fan,2,3,* Huong Q Nguyen,4 Jungeun Lee,1 Ruth Kohen,3 Jerald R Herting,5 Gustavo Matute-Bello,2,3 Sandra G Adams,6,7 Genevieve Pagalilauan,3 Soo Borson3 1School of Nursing, University of Washington, Seattle, WA, USA; 2VAPuget Sound Health Care Center, Seattle, WA, USA; 3School of Medicine, University of Washington, Seattle, WA, USA; 4Reseach and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA; 5Department of Sociology, University of Washington, Seattle, WA, USA; 6School of Medicine, University of Texas Health Science Center; 7South Texas Veterans Health Care System, San Antonio, TX, USA *These authors contributed equally to this paper Purpose: The purpose of this study was to examine the prevalence and correlates of suicidal ideation (SI in patients with stable moderate to very severe chronic obstructive pulmonary disease (COPD. Patients and methods: We conducted an exploratory mixed methods analysis of data from participants in a longitudinal observational study of depression in COPD. We measured depression with the Patient Health Questionnaire-9 (PHQ-9, which includes an item on SI. We compared participants with and without SI in relation to sociodemographics, symptoms, anxiety, and healthcare resource use with independent t-tests and chi-square tests. Content analysis was performed on qualitative data gathered during a structured SI safety assessment. Results: Of 202 participants, 121 (60% had depressive symptoms (PHQ ≥6; 51 (25% had a PHQ-9 ≥10, indicating a high likelihood of current major depression; and 22 (11% reported SI. Compared to the 99 depressed participants without SI, those with SI were more likely to be female (59% vs 27%, P=0.004; had worse dyspnea (P=0.009, depression (P<0.001, and anxiety (P=0.003; and were also more likely to have received treatment for depression and/or anxiety (82% vs 40%, P<0.001 and more hospitalizations for COPD exacerbations (P=0.03 but had similar

  2. Correlation between vacancies and magnetoresistance changes in FM manganites using the Monte Carlo method

    Energy Technology Data Exchange (ETDEWEB)

    Agudelo-Giraldo, J.D. [PCM Computational Applications, Universidad Nacional de Colombia-Sede Manizales, Km. 9 vía al aeropuerto, Manizales (Colombia); Restrepo-Parra, E., E-mail: erestrepopa@unal.edu.co [PCM Computational Applications, Universidad Nacional de Colombia-Sede Manizales, Km. 9 vía al aeropuerto, Manizales (Colombia); Restrepo, J. [Grupo de Magnetismo y Simulación, Instituto de Física, Universidad de Antioquia, A.A. 1226, Medellín (Colombia)

    2015-10-01

    The Metropolis algorithm and the classical Heisenberg approximation were implemented by the Monte Carlo method to design a computational approach to the magnetization and resistivity of La{sub 2/3}Ca{sub 1/3}MnO{sub 3}, which depends on the Mn ion vacancies as the external magnetic field increases. This compound is ferromagnetic, and it exhibits the colossal magnetoresistance (CMR) effect. The monolayer was built with L×L×d dimensions, and it had L=30 umc (units of magnetic cells) for its dimension in the x–y plane and was d=12 umc in thickness. The Hamiltonian that was used contains interactions between first neighbors, the magnetocrystalline anisotropy effect and the external applied magnetic field response. The system that was considered contains mixed-valence bonds: Mn{sup 3+eg’}–O–Mn{sup 3+eg}, Mn{sup 3+eg}–O–Mn{sup 4+d3} and Mn{sup 3+eg’}–O–Mn{sup 4+d3}. The vacancies were placed randomly in the sample, replacing any type of Mn ion. The main result shows that without vacancies, the transitions T{sub C} (Curie temperature) and T{sub MI} (metal–insulator temperature) are similar, whereas with the increase in the vacancy percentage, T{sub MI} presented lower values than T{sub C}. This situation is caused by the competition between the external magnetic field, the vacancy percentage and the magnetocrystalline anisotropy, which favors the magnetoresistive effect at temperatures below T{sub MI}. Resistivity loops were also observed, which shows a direct correlation with the hysteresis loops of magnetization at temperatures below T{sub C}. - Highlights: • Changes in the resistivity of FM materials as a function of the temperature and external magnetic field can be obtained by the Monte Carlo method, Metropolis algorithm, classical Heisenberg and Kronig–Penney approximation for magnetic clusters. • Increases in the magnetoresistive effect were observed at temperatures below T{sub MI} by the vacancies effect. • The resistive hysteresis

  3. Treatment of overlapping gaseous absorption with the correlated-k method in hot Jupiter and brown dwarf atmosphere models

    OpenAIRE

    Amundsen, David. S.; Tremblin, Pascal; Manners, James; Baraffe, Isabelle; Mayne, Nathan J.

    2016-01-01

    The correlated-k method is frequently used to speed up radiation calculations in both one-dimensional and three-dimensional atmosphere models. An inherent difficulty with this method is how to treat overlapping absorption, i.e. absorption by more than one gas in a given spectral region. We have evaluated the applicability of three different methods in hot Jupiter and brown dwarf atmosphere models, all of which have been previously applied within models in the literature: (i) Random overlap, b...

  4. Correlation functions of the antiferromagnetic Heisenberg model using a modified Lanczos method

    Science.gov (United States)

    Gagliano, Eduardo R.; Dagotto, Elbio; Moreo, Adriana; Alcaraz, Francisco C.

    1986-08-01

    Using a modified Lanczos algorithm, we study the correlation functions in the ground state of the one-dimensional antiferromagnetic Heisenberg model. We obtain numerical results for rings up to 24 sites. There are no indications of the anomalous behavior of these correlation functions recently observed in chains with 16 sites. We also present a pedagogical description of the hashing technique which is an efficient algorithm for searching and storage purposes.

  5. Cellulite: poor correlation between instrumental methods and photograph evaluation for severity classification.

    Science.gov (United States)

    Soares, J L M; Miot, H A; Sanudo, A; Bagatin, E

    2015-02-01

    Cellulite refers to skin relief alterations in women's thighs and buttocks, causing dissatisfaction and search for treatment. Its physiopathology is complex and not completely understood. Many therapeutic options have been reported with no scientific evidence about benefits. The majority of the studies are not controlled nor randomized; most efficacy endpoints are subjective, like not well-standardized photographs and investigator opinion. Objective measures could improve severity assessment. Our purpose was to correlate non-invasive instrumental measures and standardized clinical evaluation. Twenty six women presenting cellulite on buttocks, aged from 25 to 41, were evaluated by: body mass index; standardized photography analysis (10-point severity and 5-point photonumeric scales) by five dermatologists; cutometry and high-frequency ultrasonography (dermal density and dermis/hypodermis interface length). Quality of life impact was assessed. Correlations between clinical and instrumental parameters were performed. Good agreement among dermatologists and main investigator perceptions was detected. Positive correlations: body mass index and clinical scores; ultrasonographic measures. Negative correlation: cutometry and clinical scores. Quality of life score was correlated to dermal collagen density. Cellulite caused impact in quality of life. Poor correlation between objective measures and clinical evaluation was detected. Cellulite severity assessment is a challenge, and objective parameters should be optimized for clinical trials. © 2014 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  6. Rapid screening of anti-infective drug products for counterfeits using Raman spectral library-based correlation methods.

    Science.gov (United States)

    Loethen, Yvette L; Kauffman, John F; Buhse, Lucinda F; Rodriguez, Jason D

    2015-11-07

    A new spectral library-based approach that is capable of screening a diverse set of finished drug products using only an active pharmaceutical ingredient spectral library is described in this paper. This approach obviates the need for a comprehensive drug product library, thereby streamlining the use of spectral library-based tests for anti-counterfeiting efforts, specifically to target finished drug products containing the wrong active ingredient or no active ingredient at all. Both laboratory-based and portable spectrometers are used in the study to demonstrate the usefulness and transferability of the spectral correlation method for field screening. The spectral correlation between the active pharmaceutical ingredient and finished drug product spectra is calculated using both full spectral analysis and targeted spectral regions analysis of six types of antimalarial, antibiotic and antiviral products. The spectral regions were determined using a moving window spectral correlation algorithm, and the use of specific spectral regions is shown to be crucial in screening finished drug products using only the active pharmaceutical ingredient spectrum. This comprehensive screening spectral correlation method is tested on seven different validation samples from different manufacturers as those used to develop the method, as well as simulated counterfeits which were prepared to mimic falsified drugs containing no active ingredient. The spectral correlation method is successful in correctly identifying 100% of the authentic products and simulated counterfeit samples tested.

  7. Generalized-active-space pair-density functional theory: an efficient method to study large, strongly correlated, conjugated systems.

    Science.gov (United States)

    Ghosh, Soumen; Cramer, Christopher J; Truhlar, Donald G; Gagliardi, Laura

    2017-04-01

    Predicting ground- and excited-state properties of open-shell organic molecules by electronic structure theory can be challenging because an accurate treatment has to correctly describe both static and dynamic electron correlation. Strongly correlated systems, i.e., systems with near-degeneracy correlation effects, are particularly troublesome. Multiconfigurational wave function methods based on an active space are adequate in principle, but it is impractical to capture most of the dynamic correlation in these methods for systems characterized by many active electrons. We recently developed a new method called multiconfiguration pair-density functional theory (MC-PDFT), that combines the advantages of wave function theory and density functional theory to provide a more practical treatment of strongly correlated systems. Here we present calculations of the singlet-triplet gaps in oligoacenes ranging from naphthalene to dodecacene. Calculations were performed for unprecedently large orbitally optimized active spaces of 50 electrons in 50 orbitals, and we test a range of active spaces and active space partitions, including four kinds of frontier orbital partitions. We show that MC-PDFT can predict the singlet-triplet splittings for oligoacenes consistent with the best available and much more expensive methods, and indeed MC-PDFT may constitute the benchmark against which those other models should be compared, given the absence of experimental data.

  8. Evaluation of Phase Locking and Cross Correlation Methods for Estimating the Time Lag between Brain Sites: A Simulation Approach.

    Science.gov (United States)

    Soltanzadeh, Mohammad Javad; Daliri, Mohammad Reza

    2014-01-01

    Direction and latency of electrical connectivity between different sites of brain explains brain neural functionality. We compared efficiency of cross correlation and phase locking methods in time lag estimation which are based on local field potential (LFP) and LFP-spike signals, respectively. Signals recorded from MT area of a macaque's brain was used in a simulation approach. The first signal was real brain activity and the second was identical to the first one, but with two kinds of delayed and not delayed forms. Time lag between two signals was estimated by cross correlation and phase locking methods. Both methods estimated the time lags with no errors. Phase locking was not as time efficient as correlation. In addition, phase locking suffered from temporal self bias. Correlation was a more efficient method. Phase locking was not considered as a proper method to estimate the time lags between brain sites due to time inefficiency and self bias, the problems which are reported for the first time about this method.

  9. Raman correlation spectroscopy: A feasibility study of a new optical correlation technique and development of multi-component nanoparticles using the reprecipitation method

    Science.gov (United States)

    Nishida, Maki

    The feasibility of Raman correlation spectroscopy (RCS) is investigated as a new temporal optical fluctuation spectroscopy in this dissertation. RCS analyzes the correlations of the intensity fluctuations of Raman scattering from particles in a suspension that undergo Brownian motion. Because each Raman emission line arises from a specific molecular bond, the RCS method could yield diffusion behavior of specific chemical species within a dispersion. Due to the nature of Raman scattering as a coherent process, RCS could provide similar information as acquired in dynamic light scattering (DLS) and be practical for various applications that requires the chemical specificity in dynamical information. The theoretical development is discussed, and four experimental implementations of this technique are explained. The autocorrelation of the intensity fluctuations from a beta-carotene solution is obtained using the some configurations; however, the difficulty in precise alignment and weak nature of Raman scattering prevented the achievement of high sensitivity and resolution. Possible fluctuations of the phase of Raman scattering could also be affecting the results. A possible explanation of the observed autocorrelation in terms of number fluctuations of particles is also examined to test the feasibility of RCS as a new optical characterization method. In order to investigate the complex systems for which RCS would be useful, strategies for the creation of a multicomponent nanoparticle system are also explored. Using regular solution theory along with the concept of Hansen solubility parameters, an analytical model is developed to predict whether two or more components will form single nanoparticles, and what effect various processing conditions would have. The reprecipitation method was used to demonstrate the formation of the multi-component system of the charge transfer complex perylene:TCNQ (tetracyanoquinodimethane) and the active pharmaceutical ingredient cocrystal

  10. Another Form of Correlation Coefficient between Single Valued Neutrosophic Sets and Its Multiple Attribute Decision-Making Method

    Directory of Open Access Journals (Sweden)

    Jun Ye

    2013-03-01

    Full Text Available A single valued neutrosophic set (SVNS, which is the subclass of a neutrosophic set, can be considered as a powerful tool to express the indeterminate and inconsistent information in the process of decision making. Then, correlation is one of the most broadly applied indices in many fields and also an important measure in data analysis and classification, pattern recognition, decision making and so on. Therefore, we propose another form of correlation coefficient between SVNSs and establish a multiple attribute decision making method using the correlation coefficient of SVNSs under single valued neutrosophic environment. Through the weighted correlation coefficient between each alternative and the ideal alternative, the ranking order of all alternatives can be determined and the best alternative can be easily identified as well. Finally, two illustrative examples are employed to illustrate the actual applications of the proposed decision-making approach.

  11. Method for stationarity-segmentation of spike train data with application to the Pearson cross-correlation.

    Science.gov (United States)

    Quiroga-Lombard, Claudio S; Hass, Joachim; Durstewitz, Daniel

    2013-07-01

    Correlations among neurons are supposed to play an important role in computation and information coding in the nervous system. Empirically, functional interactions between neurons are most commonly assessed by cross-correlation functions. Recent studies have suggested that pairwise correlations may indeed be sufficient to capture most of the information present in neural interactions. Many applications of correlation functions, however, implicitly tend to assume that the underlying processes are stationary. This assumption will usually fail for real neurons recorded in vivo since their activity during behavioral tasks is heavily influenced by stimulus-, movement-, or cognition-related processes as well as by more general processes like slow oscillations or changes in state of alertness. To address the problem of nonstationarity, we introduce a method for assessing stationarity empirically and then "slicing" spike trains into stationary segments according to the statistical definition of weak-sense stationarity. We examine pairwise Pearson cross-correlations (PCCs) under both stationary and nonstationary conditions and identify another source of covariance that can be differentiated from the covariance of the spike times and emerges as a consequence of residual nonstationarities after the slicing process: the covariance of the firing rates defined on each segment. Based on this, a correction of the PCC is introduced that accounts for the effect of segmentation. We probe these methods both on simulated data sets and on in vivo recordings from the prefrontal cortex of behaving rats. Rather than for removing nonstationarities, the present method may also be used for detecting significant events in spike trains.

  12. Diagnosis method based on wavelet coefficient scale relativity correlation dimension for fault

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Correlation dimension as a tool to describe machinery condition is introduced.Vibration signals of the fan under different working conditions are analyzed using a threshold filtering algorithm based on the region relativity of the wavelet coefficients for reducing noise.The result shows that the characteristics of the signal could be preserved completely.The correlation dimension is able to identify conditions of the fan with faults compared with the normal condition,thereby providing an effective technology for condition monitoring and fault diagnosis of mechanical equipment.

  13. Ground State Correlations Using exp(S) Method for the ^16O Nucleus.

    Science.gov (United States)

    Mihaila, Bogdan; Heisenberg, Jochen

    1998-04-01

    We use the Argonne-v18 potential together with a phenomenological three-nucleon interaction to do the calculation of the mean-field single particle wave functions and the correlation operator describing the ground state of the ^16O nucleus. Our correlation operator includes the contributions from up to 4p4h terms. We present a breakdown of the contributions to the binding from the two- and the three-body interactions. The one- and the two-body densities for ^16O are presented. Effects of the center-of-mass correction on the charge density and form factor are also discussed.

  14. A Fast Motion Parameters Estimation Method Based on Cross-Correlation of Adjacent Echoes for Wideband LFM Radars

    Directory of Open Access Journals (Sweden)

    Yi-Xiong Zhang

    2017-05-01

    Full Text Available In wideband radar systems, the performance of motion parameters estimation can significantly affect the performance of object detection and the quality of inverse synthetic aperture radar (ISAR imaging. Although the traditional motion parameters estimation methods can reduce the range migration (RM and Doppler frequency migration (DFM effects in ISAR imaging, the computational complexity is high. In this paper, we propose a new fast non-parameter-searching method for motion parameters estimation based on the cross-correlation of adjacent echoes (CCAE for wideband LFM signals. A cross-correlation operation is carried out for two adjacent echo signals, then the motion parameters can be calculated by estimating the frequency of the correlation result. The proposed CCAE method can be applied directly to the stretching system, which is commonly adopted in wideband radar systems. Simulation results demonstrate that the new method can achieve better estimation performances, with much lower computational cost, compared with existing methods. The experimental results on real radar datasets are also evaluated to verify the effectiveness and superiority of the proposed method compared to the state-of-the-art existing methods.

  15. Correlative multiple porosimetries for reservoir sandstones with adoption of a new reference-sample-guided computed-tomographic method

    Science.gov (United States)

    Jin, Jae Hwa; Kim, Junho; Lee, Jeong-Yil; Oh, Young Min

    2016-07-01

    One of the main interests in petroleum geology and reservoir engineering is to quantify the porosity of reservoir beds as accurately as possible. A variety of direct measurements, including methods of mercury intrusion, helium injection and petrographic image analysis, have been developed; however, their application frequently yields equivocal results because these methods are different in theoretical bases, means of measurement, and causes of measurement errors. Here, we present a set of porosities measured in Berea Sandstone samples by the multiple methods, in particular with adoption of a new method using computed tomography and reference samples. The multiple porosimetric data show a marked correlativeness among different methods, suggesting that these methods are compatible with each other. The new method of reference-sample-guided computed tomography is more effective than the previous methods when the accompanied merits such as experimental conveniences are taken into account.

  16. Correlative multiple porosimetries for reservoir sandstones with adoption of a new reference-sample-guided computed-tomographic method.

    Science.gov (United States)

    Jin, Jae Hwa; Kim, Junho; Lee, Jeong-Yil; Oh, Young Min

    2016-07-22

    One of the main interests in petroleum geology and reservoir engineering is to quantify the porosity of reservoir beds as accurately as possible. A variety of direct measurements, including methods of mercury intrusion, helium injection and petrographic image analysis, have been developed; however, their application frequently yields equivocal results because these methods are different in theoretical bases, means of measurement, and causes of measurement errors. Here, we present a set of porosities measured in Berea Sandstone samples by the multiple methods, in particular with adoption of a new method using computed tomography and reference samples. The multiple porosimetric data show a marked correlativeness among different methods, suggesting that these methods are compatible with each other. The new method of reference-sample-guided computed tomography is more effective than the previous methods when the accompanied merits such as experimental conveniences are taken into account.

  17. Correlated, Static and Dynamic Polarizabilities of Small Molecules. Comparison of Four "Black Box" Methods

    DEFF Research Database (Denmark)

    Dalskov, Erik K.; Sauer, Stephan P. A.

    1998-01-01

    were employed, Sadlej's medium size polarized basis set and Dunning's correlation consistent basis set of triple- quality augmented by two diffuse functions of each angular momentum (daug-cc-pVTZ). The results are compared to other theoretical results as well as to experimental values for the static...

  18. Analytical and Numerical Characterization of Autocorrelation and Perturbation-Correlation Moving-Window Methods.

    Science.gov (United States)

    Lee, Young Jong

    2017-01-01

    Moving-window (MW) approaches to two-dimensional correlation spectroscopy (2D-COS) make it possible to characterize spectral changes occurring in a narrow range of perturbation variable (e.g., time, temperature, and concentration). Despite the wide range of application, the physical meanings of MW correlation intensities have been only qualitatively associated with the direction and curvature of spectral intensity change with regard to a perturbation variable. Here are full and simplified analytical expressions of autocorrelation moving-window (ACMW) and synchronous and asynchronous perturbation-correlation moving-window ( s-PCMW and as-PCMW) intensities. When the window is set sufficiently narrower than the bandwidth of spectral change, the square root of ACMW intensity and s-PCMW intensity becomes proportional to the first order derivative, and as-PCMW intensity becomes proportional to the negative of the second order derivative. This paper demonstrates that both ACMW and PCMW profiles can be significantly altered by non-uniform perturbation spacing. It is also found that intensity noise can cause ACMW to display a false offset drift. This analytical and numerical characterization of the two MW correlation intensities elucidates their physical meanings and ascertains the analysis conditions for reliable interpretation.

  19. Determination of velocity vector angles using the directional cross-correlation method

    DEFF Research Database (Denmark)

    Kortbek, Jacob; Jensen, Jørgen Arendt

    2005-01-01

    with a normal transmission of a focused ultrasound field. The velocity profile estimates from simulations have relative mean standard deviations between 0 . 7% and 7 . 7% for flow between 45 ◦ and 90 ◦ . The angle estimation performance is highly dependent on the choice of the time k tprf · T prf ( correlation...

  20. Ground state correlations and mean field using the exp(S) method

    CERN Document Server

    Heisenberg, J H; Heisenberg, Jochen H.; Mihaila, Bogdan

    1999-01-01

    This document gives a detailed account of the terms used in the computation of the ground state mean field and the ground state correlations. While the general approach to this description is given in a separate paper (nucl-th/9802029) we give here the explicite expressions used.

  1. Correlation between feeding methods, non-nutritive sucking and orofacial behaviors.

    Science.gov (United States)

    Medeiros, Ana Paula Magalhães; Ferreira, José Tarcísio Lima; Felício, Cláudia Maria de

    2009-01-01

    The development of oral motor control depends partially on motor and sensory experiences. To analyze the relationship between the duration of breastfeeding, artificial feeding and sucking habits, and of these parameters with the orofacial motor performance. Participants of this study were one hundred and seventy-six children aged 6 to 12 years. All subjects were submitted to an orofacial myofunctional clinical examination, using a protocol with scores, and parents/care takers were interviewed in respect to the feeding and sucking habits of their children. Correlations were calculated using the Spearman Test. In the studied sample, the mean duration of breastfeeding was of 10.30 months (ranging from zero to 60 months), of artificial feeding was of 44.12 months (zero to 122 months) and of sucking habits was of 39.32 months (0 to 144 months). There was a negative correlation of breastfeeding duration with artificial feeding duration and sucking habits duration (p artificial feeding was positively correlated to the duration of sucking habits (p breastfeeding was positively correlated with the mobility of the tongue and jaw (p = 0.05). There was a negative correlation of the duration of artificial feeding and the duration of sucking habits with the performance in mastication and swallowing, respectively, as well as with the duration of both types of sucking with the performance in the diadochokinesia test (p = 0.05). The duration of natural breastfeeding presented a positive effect over the mobility of the orofacial structures. Deleterious effects of the prolonged duration of artificial feeding and sucking habits in the oral motor control were confirmed.

  2. PERFORMANCE OF RIDGE REGRESSION ESTIMATOR METHODS ON SMALL SAMPLE SIZE BY VARYING CORRELATION COEFFICIENTS: A SIMULATION STUDY

    Directory of Open Access Journals (Sweden)

    Anwar Fitrianto

    2014-01-01

    Full Text Available When independent variables have high linear correlation in a multiple linear regression model, we can have wrong analysis. It happens if we do the multiple linear regression analysis based on common Ordinary Least Squares (OLS method. In this situation, we are suggested to use ridge regression estimator. We conduct some simulation study to compare the performance of ridge regression estimator and the OLS. We found that Hoerl and Kennard ridge regression estimation method has better performance than the other approaches.

  3. Single-step scanner-based digital image correlation (SB-DIC) method for large deformation mapping in rubber

    Science.gov (United States)

    Goh, C. P.; Ismail, H.; Yen, K. S.; Ratnam, M. M.

    2017-01-01

    The incremental digital image correlation (DIC) method has been applied in the past to determine strain in large deformation materials like rubber. This method is, however, prone to cumulative errors since the total displacement is determined by combining the displacements in numerous stages of the deformation. In this work, a method of mapping large strains in rubber using DIC in a single-step without the need for a series of deformation images is proposed. The reference subsets were deformed using deformation factors obtained from the fitted mean stress-axial stretch ratio curve obtained experimentally and the theoretical Poisson function. The deformed reference subsets were then correlated with the deformed image after loading. The recently developed scanner-based digital image correlation (SB-DIC) method was applied on dumbbell rubber specimens to obtain the in-plane displacement fields up to 350% axial strain. Comparison of the mean axial strains determined from the single-step SB-DIC method with those from the incremental SB-DIC method showed an average difference of 4.7%. Two rectangular rubber specimens containing circular and square holes were deformed and analysed using the proposed method. The resultant strain maps from the single-step SB-DIC method were compared with the results of finite element modeling (FEM). The comparison shows that the proposed single-step SB-DIC method can be used to map the strain distribution accurately in large deformation materials like rubber at much shorter time compared to the incremental DIC method.

  4. Ground State Correlations Using exp(S) Method for the Argonne-v18 Potential.

    Science.gov (United States)

    Heisenberg, Jochen; Mihaila, Bogdan

    1997-04-01

    We use the Argonne-v18 potential together with the phenomenological three-nucleon interaction to do the calculation of the mean-field single particle wave functions and the correlation operator S for ^16O. Our correlation operator includes the contributions from up to 4p4h terms. From the three-nucleon interaction we include only those terms that can be written as a density dependent two-body term. We present a breakdown of the contributions to the binding from the two- and the three-body interactions. The one- and the two-body densities for ^16O are presented. Effects of the center-of-mass correction on the charge density and form factor are also discussed.

  5. Research Methods Identifying Correlation Between Physical Environment of Schools and Educational Paradigms

    Directory of Open Access Journals (Sweden)

    Grėtė Brukštutė

    2016-04-01

    Full Text Available The article is analysing the research that was already carried out in order to determine correlation between a physical environment of schools and educational paradigms. While selecting materials for the analysis, the attention was focused on studies conducted in the USA and European countries. Based on these studies the methodological attitudes towards coherence of the education and spatial structures were tried to identify. Homogeneity and conformity of an educational character and a physical learning environment became especially important during changes of educational conceptions. The issue how educational paradigms affect the architecture of school buildings is not yet analysed in Lithuania, therefore the results of this research could actualize a theme on correlation between educational paradigms and the architecture of school buildings and form initial guidelines for the development of the modern physical learning environment.

  6. Variability and correlations in muskmelon in relation to the cultivation method.

    Science.gov (United States)

    Molina, R V; Nuez, F; Cuartero, J; Goméz-Guillamón, M L; Abadía, J

    1989-09-01

    Six fruit characters have been measured in 23 cultivars of Cucumis melo, representing a wide geographical range. Plants were grown both in the greenhouse and in the field. When the 23 cultivars were analyzed together, the largest component of variance was found between cultivars under both growth conditions, suggesting the existence of large genetic diversity for all the characters studied. Generally, variance between plants within cultivars was less than or equal to variance between fruits within plant. This indicates that environmental variation is the most important part of the variation within cultivars. Correlations between pairs of characters at cultivar, plant and fruit levels were calculated from the variance-covariance components. In the majority of paired traits, the correlation values indicated that genetic and environmental factors may act in the same direction.

  7. A Non-Simulation Based Method for Inducing Pearson’s Correlation Between Input Random Variables

    Science.gov (United States)

    2008-04-23

    Thanks to Dr. Steven Book of MCR for his help in obtaining copies of several papers on correlation modules, without which this paper would not have been...risks, not estimating variation SWBS Description Upside Probable Downside 000 Administration 100 Hull 200 Propulsion 300 Electric Plant 400 Electonics ...Systems 500 Auxillary Systems 600 Outfit & Furnishings 700 Weapons 800 Integration & Engineering 900 Ship Assembly & Support Total SWBS Description

  8. Two-Way Gene Interaction From Microarray Data Based on Correlation Methods

    OpenAIRE

    Alavi Majd, Hamid; Talebi, Atefeh; Gilany, Kambiz; Khayyer, Nasibeh

    2016-01-01

    Background Gene networks have generated a massive explosion in the development of high-throughput techniques for monitoring various aspects of gene activity. Networks offer a natural way to model interactions between genes, and extracting gene network information from high-throughput genomic data is an important and difficult task. Objectives The purpose of this study is to construct a two-way gene network based on parametric and nonparametric correlation coefficients. The first step in const...

  9. DAMAGE AND FRACTURE EVALUATION OF GRANULAR COMPOSITE MATERIALS BY DIGITAL IMAGE CORRELATION METHOD

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jue; XIONG Chunyang; LI Hongju; LI Ming; WANG Jianxiang; FANG Jing

    2004-01-01

    This paper presents the applications of digital image correlation technique to the mesoscopic damage and fracture study of some granular based composite materials including steelfiber reinforced concrete, sandstone and crystal-polymer composite. The deformation fields of the composite materials resulted from stress localization were obtained by the correlation computation of the surface images with loading steps and thus the related damage prediction and fracture parameters were evaluated. The correlation searching could be performed either directly based on the gray levels of the digital images or from the wavelet transform (WT) coefficients of the transform spectrum. The latter was developed by the authors and showed higher resolution and sensitivity to the singularity detection.Because the displacement components came from the rough surfaces of the composite materials without any coats of gratings or fringes of optical interferometry, both surface profiles and the deformation fields of the composites were visualized which was helpful to compare each other to analyze the damage of those heterogeneous materials.

  10. Investigation of correlation effects in FeSe and FeTe by LDA + U method

    Energy Technology Data Exchange (ETDEWEB)

    Lohani, H.; Mishra, P.; Sekhar, B.R., E-mail: sekhar@iopb.res.in

    2015-05-15

    Highlights: • Comparative study of the influence of U and J in FeSe and FeTe. • We found correlation effects are strong in Fe-3d orbitals in FeSe and FeTe. • Correlation effects are orbital selective in nature. - Abstract: We present a comparative study of the influence of Coulomb interaction and Hund’s coupling on the electronic structure of FeSe and FeTe. Our calculations are based on density functional theory (DFT) with local density approximation (LDA + U) framework employed in TB-LMTO ASA code. We found the correlation effects are orbital selective due to the strength of interorbital hybridization among the different Fe-3d orbitals mediated via the chalcogen (Se/Te-p) orbitals and are different in both the compounds. The Coulomb interaction is screened significantly by Te-p bands in FeTe. Similarly the orbital selection is different in both the compounds because of the difference in the chalcogen height.

  11. Geminal-spanning orbitals make explicitly correlated reduced-scaling coupled-cluster methods robust, yet simple

    Science.gov (United States)

    Pavošević, Fabijan; Neese, Frank; Valeev, Edward F.

    2014-08-01

    We present a production implementation of reduced-scaling explicitly correlated (F12) coupled-cluster singles and doubles (CCSD) method based on pair-natural orbitals (PNOs). A key feature is the reformulation of the explicitly correlated terms using geminal-spanning orbitals that greatly reduce the truncation errors of the F12 contribution. For the standard S66 benchmark of weak intermolecular interactions, the cc-pVDZ-F12 PNO CCSD F12 interaction energies reproduce the complete basis set CCSD limit with mean absolute error <0.1 kcal/mol, and at a greatly reduced cost compared to the conventional CCSD F12.

  12. A method for the estimation of the significance of cross-correlations in unevenly sampled red-noise time series

    CERN Document Server

    Max-Moerbeck, W; Hovatta, T; Pavlidou, V; Pearson, T J; Readhead, A C S

    2014-01-01

    We present a practical implementation of a Monte Carlo method to estimate the significance of cross-correlations in unevenly sampled time series of data, whose statistical properties are modeled with a simple power-law power spectral density. This implementation builds on published methods, we introduce a number of improvements in the normalization of the cross-correlation function estimate and a bootstrap method for estimating the significance of the cross-correlations. A closely related matter is the estimation of a model for the light curves, which is critical for the significance estimates. We present a graphical and quantitative demonstration that uses simulations to show how common it is to get high cross-correlations for unrelated light curves with steep power spectral densities. This demonstration highlights the dangers of interpreting them as signs of a physical connection. We show that by using interpolation and the Hanning sampling window function we are able to reduce the effects of red-noise leak...

  13. Algebraic connectivity analysis in molecular electronic structure theory II: total exponential formulation of second-quantised correlated methods

    Science.gov (United States)

    Lyakh, Dmitry I.; Bartlett, Rodney J.

    2014-01-01

    The fundamentality of the exponential representation of a second-quantised correlated wave function is emphasised with an accent on the physical sense of cluster amplitudes as cumulants of the correlated ansatz. Three main wave function formalisms, namely, the configuration-interaction theory, the coupled-cluster approach, and the many-body perturbation theory (as well as their extensions, e.g. the equation-of-motion coupled-cluster method, multireference schemes, etc.), are represented in an exponential form, leading to a formulation of the working equations in terms of cluster amplitudes. By expressing the corresponding many-body tensor equations in terms of cluster amplitudes, we could unambiguously check connectivity types and the asymptotic behaviour of all tensors/scalars involved (in the formal limit of an infinite number of correlated particles). In particular, the appearance of disconnected cluster amplitudes corresponds to unphysical correlations. Besides, we demonstrate that the equation-of-motion coupled-cluster approach, as well as certain excited-state configuration-interaction methods, can be recast in a fully connected (exponential) form, thus breaking the common belief that all truncated configuration-interaction methods violate connectivity. Our work is based on the recently developed algebraic framework which can be viewed as a complement to the classical diagrammatic analysis.

  14. Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation.

    Science.gov (United States)

    Ottesen, Johnny T; Mehlsen, Jesper; Olufsen, Mette S

    2014-11-01

    We consider the inverse and patient specific problem of short term (seconds to minutes) heart rate regulation specified by a system of nonlinear ODEs and corresponding data. We show how a recent method termed the structural correlation method (SCM) can be used for model reduction and for obtaining a set of practically identifiable parameters. The structural correlation method includes two steps: sensitivity and correlation analysis. When combined with an optimization step, it is possible to estimate model parameters, enabling the model to fit dynamics observed in data. This method is illustrated in detail on a model predicting baroreflex regulation of heart rate and applied to analysis of data from a rat and healthy humans. Numerous mathematical models have been proposed for prediction of baroreflex regulation of heart rate, yet most of these have been designed to provide qualitative predictions of the phenomena though some recent models have been developed to fit observed data. In this study we show that the model put forward by Bugenhagen et al. can be simplified without loss of its ability to predict measured data and to be interpreted physiologically. Moreover, we show that with minimal changes in nominal parameter values the simplified model can be adapted to predict observations from both rats and humans. The use of these methods make the model suitable for estimation of parameters from individuals, allowing it to be adopted for diagnostic procedures.

  15. A Method to Optimize Geometric Errors of Machine Tool based on SNR Quality Loss Function and Correlation Analysis

    Directory of Open Access Journals (Sweden)

    Cai Ligang

    2017-01-01

    Full Text Available Instead improving the accuracy of machine tool by increasing the precision of key components level blindly in the production process, the method of combination of SNR quality loss function and machine tool geometric error correlation analysis to optimize five-axis machine tool geometric errors will be adopted. Firstly, the homogeneous transformation matrix method will be used to build five-axis machine tool geometric error modeling. Secondly, the SNR quality loss function will be used for cost modeling. And then, machine tool accuracy optimal objective function will be established based on the correlation analysis. Finally, ISIGHT combined with MATLAB will be applied to optimize each error. The results show that this method is reasonable and appropriate to relax the range of tolerance values, so as to reduce the manufacturing cost of machine tools.

  16. MIMO-OFDM channel estimation method utilizing correlation in time domain for B3G-TDD uplink

    Institute of Scientific and Technical Information of China (English)

    ZHOU Ming-yu; LI Li-hua; JIANG Jun; ZHONG Ming-hua; TAG Xiao-feng

    2007-01-01

    This article proposes a simple pilot-aided channel estimation method based on correlation in time domain for multiple-input and multiple-output orthogonal frequency division multiplexing (MIMO-OFDM) systems. Pilot symbols in all transmit antennas are generated from different circular shifting of a certain sequence. Through once correlation, the receiver can obtain time-domain pulse responses for channel fading from all transmit antennas to a certain receive antenna, from which channel estimation in frequency domain can be obtained. Beyond 3G time-division duplex (B3G-TDD) uplink is introduced, and the channel estimation method is used in it. Theoretical analysis and simulation are both carried out. Mean square error (MSB) performance shows that the method can exhibit precise estimation. Complexity analysis proves it requires very low complexity. System simulation result shows that it guarantees the performance of B3G-TDD uplink very well.

  17. A Method for Incipient Fault Diagnosis of Roller Bearings Based on the Wavelet Transform Correlation Filter and Hilbert Transform

    Institute of Scientific and Technical Information of China (English)

    ZENG Qing-hu; QIU Jing; LIU Guan-jun

    2007-01-01

    Noise is the biggest obstacle that makes the incipient fault diagnosis results of roller bearings uncorrected; a new method for diagnosing incipient fault of roller bearings based on the Wavelet Transform Correlation Filter and Hilbert Transform was proposed. First, the weak fault information features are picked up from the roller bearings fault vibration signals by use of a de-noising characteristic of the Wavelet Transform Correlation Filter as the preprocessing of the Hilbert Envelope Analysis. Then, in order to get fault features frequency, de-noised wavelet coefficients of high scales which represent high frequency signal were analyzed by Hilbert Envelope Spectrum Analysis. The simulation signals and diagnosing examples analysis results reveal that the proposed method is more effective than the method of direct wavelet coefficients-Hilbert Transform in de-noising and clarifying roller bearing incipient fault.

  18. Correlation between scores on integration of scientific knowledge and achievement in a course in educational research methods.

    Science.gov (United States)

    Onwuegbuzie, A J

    2001-04-01

    The purpose of this study was to investigate the correlations between students' scores on integrating science knowledge and their conceptual knowledge of educational research concepts, methods, and applications. Participants were 124 graduate students enrolled in several sections of a required introductory course in educational research methods. Students' integration of science knowledge was measured via the Test of Integrated Process Skills II, and performance in the educational research methods class was assessed via midterm and final examinations. Analysis indicated that correlations between scores on the Test of Integrated Process Skills II and achievement in the course on midterm and final examinations were .36 and .42, respectively, suggesting that those who were more able to integrate science knowledge also tended to exhibit higher performance on the examinations.

  19. A Rapid Identification Method for Calamine Using Near-Infrared Spectroscopy Based on Multi-Reference Correlation Coefficient Method and Back Propagation Artificial Neural Network.

    Science.gov (United States)

    Sun, Yangbo; Chen, Long; Huang, Bisheng; Chen, Keli

    2017-07-01

    As a mineral, the traditional Chinese medicine calamine has a similar shape to many other minerals. Investigations of commercially available calamine samples have shown that there are many fake and inferior calamine goods sold on the market. The conventional identification method for calamine is complicated, therefore as a result of the large scale of calamine samples, a rapid identification method is needed. To establish a qualitative model using near-infrared (NIR) spectroscopy for rapid identification of various calamine samples, large quantities of calamine samples including crude products, counterfeits and processed products were collected and correctly identified using the physicochemical and powder X-ray diffraction method. The NIR spectroscopy method was used to analyze these samples by combining the multi-reference correlation coefficient (MRCC) method and the error back propagation artificial neural network algorithm (BP-ANN), so as to realize the qualitative identification of calamine samples. The accuracy rate of the model based on NIR and MRCC methods was 85%; in addition, the model, which took comprehensive multiple factors into consideration, can be used to identify crude calamine products, its counterfeits and processed products. Furthermore, by in-putting the correlation coefficients of multiple references as the spectral feature data of samples into BP-ANN, a BP-ANN model of qualitative identification was established, of which the accuracy rate was increased to 95%. The MRCC method can be used as a NIR-based method in the process of BP-ANN modeling.

  20. Shocking fault component of abnormal sound signal in the fault engine extract method based on linear superposition method and cross-correlation analysis

    Directory of Open Access Journals (Sweden)

    Dayong Ning

    2015-08-01

    Full Text Available An extracted fault component of an abnormal sound is useful for faulty diagnosis. The existing fault component extracting approaches based on time–frequency analysis should filter the original signal to eliminate the background noise. However, these approaches will significantly change the fault component. In this article, a method for extracting the fault component of an abnormal sound signal is presented. This method is based on the linear superposition method and cross-correlation analysis. The method can eliminate the background noise and acquire the waveform of fault component. According to the feature of the shocking fault component, the acquired signal was intercepted into several segments, and the cross-correlation analysis was adopted to remove the wrong segment without the fault shocking component. The correct components were then linearly superposed together to eliminate the background noise. Finally, two experiments were performed to evaluate the effectiveness of the proposed fault component extracting method. The results show that the approach satisfactorily extracts the fault shocking component. The precise faulty component can be extracted by this method, which judges the engine condition precisely. The fault type can be diagnosed easily by this method. This method can be used in other fields to extract a particular component from a complicated signal.

  1. CORRELATION OF AATCC TEST METHOD 150 TO AATCC TEST METHOD 61 FOR USE WITH LAUNDERING DURABILITY STUDIES OF RETROREFLECTIVE ITEMS AS DEFINED IN PURCHASE DESCRIPTION CO/PD 06 05A

    Science.gov (United States)

    2017-06-02

    TECHNICAL REPORT AD ________________ NATICK/TR-17/015 CORRELATION OF AATCC...Final 3. DATES COVERED (From - To) October 2014 – April 2016 4. TITLE AND SUBTITLE CORRELATION OF AATCC TEST METHOD 150 TO AATCC TEST METHOD 61 FOR...data to the support the correlation between 5 laundering cycles of the America Association of Textile Chemists & Colorists Test Method 61

  2. Zero Field Splitting of the chalcogen diatomics using relativistic correlated wave-function methods

    DEFF Research Database (Denmark)

    Rota, Jean-Baptiste; Knecht, Stefan; Fleig, Timo;

    2011-01-01

    ) methods are used as well as two-step methods Spin-Orbit Complete Active Space Perturbation Theory at 2nd order (SO-CASPT2) and Spin-Orbit Difference Dedicated Configuration Interaction (SODDCI). The energy of the X21 state corresponds to the Zero-Field Splitting (ZFS) of the ground state spin triplet...

  3. A Correlated Microwave-Acoustic Imaging method for early-stage cancer detection.

    Science.gov (United States)

    Gao, Fei; Zheng, Yuanjin

    2012-01-01

    Microwave-based imaging technique shows large potential in detecting early-stage cancer due to significant dielectric contrast between tumor and surrounding healthy tissue. In this paper, we present a new way named Correlated Microwave-Acoustic Imaging (CMAI) of combining two microwave-based imaging modalities: confocal microwave imaging(CMI) by detecting scattered microwave signal, and microwave-induced thermo-acoustic imaging (TAI) by detecting induced acoustic signal arising from microwave energy absorption and thermal expansion. Necessity of combining CMI and TAI is analyzed theoretically, and by applying simple algorithm to CMI and TAI separately, we propose an image correlation approach merging CMI and TAI together to achieve better performance in terms of resolution and contrast. Preliminary numerical simulation shows promising results in case of low contrast and large variation scenarios. A UWB transmitter is designed and tested for future complete system implementation. This preliminary study inspires us to develop a new medical imaging modality CMAI to achieve real-time, high resolution and high contrast simultaneously.

  4. A new access density definition and its correlation with crash rates by microscopic traffic simulation method.

    Science.gov (United States)

    Huang, Bing; Zhang, Yu; Lu, Linjun; Lu, Jian John

    2014-03-01

    Better access management can improve highway safety by reducing potential crashes and conflicts. To make adequate access management decisions, it is essential to understand the impact of different access types on roadway safety, usually represented by the crash rate of a roadway segment. The objective of this paper is to propose a new access density definition reflecting the impact of traffic speed variation of different access types. The traffic speed variation was obtained from a microscopic traffic simulation software package TSIS-CORSIM. A sample roadway Temple Terrace Highway was selected to perform traffic simulation. Access Weight was obtained from traffic speed variation, and access density was obtained from access weight. The proposed access density was then compared with the existing definition by analyzing their correlations with crash rates on one suburban street in Temple Terrace, Florida. The comparison demonstrates that crash rates are more highly correlated with the proposed access density than that in the previous study, which is helpful for Federal Highway Administration (FHWA), United States Department of Transportation (USDOT), and transportation consulting companies to regulate the construction, management and design of roadway segments.

  5. Evaluation of recombinant human parathyroid hormone by CZE method and its correlation with in vitro bioassay and LC methods.

    Science.gov (United States)

    Maldaner, Fernanda Pavani Stamm; Perobelli, Rafaela Ferreira; Xavier, Bruna; Remuzzi, Gabriel Lunardi; Walter, Maurício Elesbão; Dalmora, Sérgio Luiz

    2017-01-01

    A stability-indicating capillary zone electrophoresis (CZE) method was validated to assess the content/potency of the recombinant human parathyroid hormone (rhPTH 1-34), using ranitidine as internal standard (IS). A fused-silica capillary, (i.d. of 50µm; effective length of 40cm) was used at 25°C; the applied voltage was 20kV. The background electrolyte solution consisted of 50mmolL(-1) sodium dihydrogen phosphate solution at pH 3.0. Injections were performed using a pressure mode at 50 mbar for 45s, with detection by photodiode array (PDA) detector set at 200nm. Separation was obtained with a migration time of 5.3min, and was linear over the concentration range of 0.25-250µgmL(-1) (r(2) =0.9992). Specificity and stability-indicating capability were established in degradation studies, which also showed that there was no interference of the excipients. The accuracy was 100.28% with bias lower than 0.85%. Analyses of the same batches showed mean differences of the estimated content/potencies of 0.61%, 1.31% higher and 0.86% lower as compared to the validated reversed-phase and size exclusion liquid chromatography methods, and to the UMR-106 cell culture bioassay, respectively, with non-significant differences (p>0.05). Degraded forms were also subjected to the in vitro cytotoxicity test. The results obtained showed the capabilities of each one of the methods, and constitute an alternative strategy to monitor stability, improve the quality control and ensure the batch-to-batch consistency of bulk and finished biotechnology-derived medicine.

  6. Correlative methods for dual-species quantum tests of the weak equivalence principle

    CERN Document Server

    Barrett, B; Chichet, L; Battelier, B; Gominet, P -A; Bertoldi, A; Bouyer, P; Landragin, A

    2015-01-01

    Matter-wave interferometers utilizing non-identical elements intrinsically have different sensitivities, and the analysis tools available until now are insufficient for accurately estimating the atomic phase difference under many experimental conditions. In this work, we describe and demonstrate two new methods for extracting the differential phase between dual-species atom interferometers for precise tests of the weak equivalence principle. The first method is a generalized Bayesian analysis, which uses knowledge of the system noise to estimate the differential phase based on a statistical model. The second method utilizes a mechanical accelerometer to reconstruct single-sensor interference fringes based on measurements of the vibration-induced phase. An improved ellipse-fitting algorithm is also implemented as a third method for comparison. These analysis tools are investigated using both numerical simulations and experimental data from simultaneous $^{87}$Rb and $^{39}$K interferometers, and both new techn...

  7. [Cross-correlation as a method for discriminating impulses on multineuronal recordings].

    Science.gov (United States)

    Bogdanov, A V; Galashina, A G

    1989-01-01

    Impulses series, singled out from multineuronal activity by means of amplitude discriminator, were analyzed by creating crosscorrelation histograms. The authors consider that in studying of net brain activity with crosscorrelation method of analysis "window" discrimination of impulses series in multineuronal record is a quite correct method and may be used along with discrimination of spikes by form. It is shown that the size of the "window", used for singling out of separate impulses series, is not a determining parameter in search of temporal dependence in the activity of the investigated cells, as final discrimination of the impulses of dependently acting neuronal pairs occurs at the level of the crosscorrelation method itself. The step of the analysis under the use of crosscorrelation method is of decisive significance for revealing of direct interconnections between neurones in the cases when these connections are masked on histograms with wide peaks reflecting the influences of common sources, on the recorded cells.

  8. Methods of correlating electropenetrography waveform data to Hemipteran probing behavior and pathogen transmission

    Science.gov (United States)

    Hemipteran feeding behavior cannot be visualized within plant tissues by researchers studying probing and/or transmission attributes of some economically important plant pathogens transmitted by these piercing sucking insects. Electropenetrography (EPG) is currently the most precise method for study...

  9. The method of the correlation and dispersion defining of the total power components in the electric transport devices

    Directory of Open Access Journals (Sweden)

    A. V. Nikitenko

    2013-04-01

    Full Text Available Purpose. Development and theoretical ground of the analytical method for the calculation of the active, reactive and total powers in the electric traction devices, taking into consideration the non-stationary character of the stochastic processes change of the voltage and current in the elements of these systems. Methodology. The mathematical methods of the random processes theory and the “discrete electrical engineering” methods are used for solving the main problem of this paper. Findings. The Method of the Correlation and Dispersion is developed for definition of the active power, the reactive power by Fryse and the total power of the devices in the elements of the electric traction system of the main-line railways. The method is based on the well-known concepts of auto- and inter-correlation functions of the random processes which govern the feeder voltages and the currents in the traction power supply subsystem as well as the currents and voltages of the electric rolling stock. The method developed in this paper allows estimating the powers of both stationary and non-stationary processes. This method can be used for the analysis of both the traction mode and the regenerative braking mode of the electric rolling stock. The total power components were calculated for the one of the feeder areas of the Prydniprovsk railway using this method. The results show the significant flow of the reactive power in the traction power supply system. This fact is also confirmed by the high values of the reactive power coefficient. Originality. Scientific novelty of the research is consisted in the following. Firstly, for defining the active and reactive powers in elements of the traction power supply system the new method (the Method of Correlation and Dispersion is created and grounded. This method is different from other existing methods because it takes into consideration the varying non-stationary character of the chance processes of the feeder and

  10. A Monte Carlo Method for Multi-Objective Correlated Geometric Optimization

    Science.gov (United States)

    2014-05-01

    performs a Monte Carlo optimization to provide geospatial intelligence on entity placement using OpenCL framework. The solutions for optimal...Geometric optimization,Monte Carlo method, parallel computing, OpenCL 22 Song J. Park 410-278-5444Unclassified Unclassified Unclassified UU ii...given threat and target positions, and • AMonte Carlo method development in the OpenCL programming model for vendor-agnostic architecture support and

  11. Acoustic signal detection through the cross-correlation method in experiments with different signal to noise ratio and reverberation conditions

    CERN Document Server

    Adrián-Martínez, S; Bou-Cabo, M; Felis, I; Llorens, C; Martínez-Mora, J A; Saldaña, M

    2015-01-01

    The study and application of signal detection techniques based on cross-correlation method for acoustic transient signals in noisy and reverberant environments are presented. These techniques are shown to provide high signal to noise ratio, good signal discernment from very close echoes and accurate detection of signal arrival time. The proposed methodology has been tested on real data collected in environments and conditions where its benefits can be shown. This work focuses on the acoustic detection applied to tasks of positioning in underwater structures and calibration such those as ANTARES and KM3NeT deep-sea neutrino telescopes, as well as, in particle detection through acoustic events for the COUPP/PICO detectors. Moreover, a method for obtaining the real amplitude of the signal in time (voltage) by using cross correlation has been developed and tested and is described in this work.

  12. Unsupervised Method for Correlated Noise Removal for Multi-wavelength Exo-planet Transit Observations

    Science.gov (United States)

    Dehghan Firoozabadi, Ali; Diaz, Alejandro; Rojo, Patricio; Soto, Ismael; Mahu, Rodrigo; Becerra Yoma, Nestor; Sedaghati, Elyar

    2017-07-01

    Exoplanetary atmospheric observations require an exquisite precision in the measurement of the relative flux among wavelengths. In this paper, we aim to provide a new adaptive method to treat light curves before fitting transit parameters in order to minimize systematic effects that affect, for instance, ground-based observations of exo-atmospheres. We propose a neural-network-based method that uses a reference built from the data itself with parameters that are chosen in an unsupervised fashion. To improve the performance of proposed method, K-means clustering and Silhouette criteria are used for identifying similar wavelengths in each cluster. We also constrain under which circumstances our method improves the measurement of planetary-to-stellar radius ratio without producing significant systematic offset. We tested our method in high quality data from WASP-19b and low-quality data from GJ-1214. We succeed in providing smaller error bars for the former when using JKTEBOP, but GJ-1214 light curve was beyond the capabilities of this method to improve as it was expected from our validation tests.

  13. Fast method of constructing image correlations to build a free network based on image multivocabulary trees

    Science.gov (United States)

    Zhan, Zongqian; Wang, Xin; Wei, Minglu

    2015-05-01

    In image-based three-dimensional (3-D) reconstruction, one topic of growing importance is how to quickly obtain a 3-D model from a large number of images. The retrieval of the correct and relevant images for the model poses a considerable technological challenge. The "image vocabulary tree" has been proposed as a method to search for similar images. However, a significant drawback of this approach is identified in its low time efficiency and barely satisfactory classification result. The method proposed is inspired by, and improves upon, some recent methods. Specifically, vocabulary quality is considered and multivocabulary trees are designed to improve the classification result. A marked improvement was, indeed, observed in our evaluation of the proposed method. To improve time efficiency, graphics processing unit (GPU) computer unified device architecture parallel computation is applied in the multivocabulary trees. The results of the experiments showed that the GPU was three to four times more efficient than the enumeration matching and CPU methods when the number of images is large. This paper presents a reliable reference method for the rapid construction of a free network to be used for the computing of 3-D information.

  14. Brillouin optical correlation analysis system using a simplified frequency-modulated time division method

    Science.gov (United States)

    Choi, Bo-Hun; Kwon, Il-Bum

    2014-01-01

    A time-division Brillouin optical correlation domain analysis system was successfully achieved using simplified laser diode (LD) modulation and pump lightwave optimization. A complicated transfer function for a precise output waveform of a LD was required for the conventional system. However, a very simple modulation function gave a power output very close to a required ideal rectangle waveform without sacrificing optical output spectrum. An electrical input waveform applied into a gate in the pump lightwave path was also optimized for eliminating a probe lightwave included in a pump lightwave and for passing consecutive pump pulses alternatively. So the stimulated Brillouin scattering gain was attained without seriously distorting FM modulation, and the targeted spatial resolution was clearly accomplished. Additionally, using high speed response of a semiconductor optical amplifier (SOA), unlike an erbium-doped fiber amplifier (EDFA), the possibility was investigated that an SOA was going to replace an EDFA and a modulator used as a gate in the same time.

  15. Investigation of correlation effects in FeSe and FeTe by LDA + U method

    Science.gov (United States)

    Lohani, H.; Mishra, P.; Sekhar, B. R.

    2015-05-01

    We present a comparative study of the influence of Coulomb interaction and Hund's coupling on the electronic structure of FeSe and FeTe. Our calculations are based on density functional theory (DFT) with local density approximation (LDA + U) framework employed in TB-LMTO ASA code. We found the correlation effects are orbital selective due to the strength of interorbital hybridization among the different Fe-3d orbitals mediated via the chalcogen (Se/Te-p) orbitals and are different in both the compounds. The Coulomb interaction is screened significantly by Te-p bands in FeTe. Similarly the orbital selection is different in both the compounds because of the difference in the chalcogen height.

  16. Correlation of the "EMIT" antiepileptic drug assay with a gas liquid chromatographic method.

    Science.gov (United States)

    Legaz, M; Raisys, V A

    1976-02-01

    Many methodologies have been developed for determining anticonvulsant drug levels in human serum. Unfortunately, most procedures are either time consuming or subject to a variety of interferring substances. The "Enzyme Multiplied Immunoassay Technique" (EMIT) system has been evaluated for its speed, sensitivity, accuracy, and precision. When compared with a gas-liquid chromatographic procedure, the EMIT assay appeared to yield results which were statistically comparable for the drugs diphenylhydantoin, phenobarbital, and primidone. The EMIT assay also demonstrated no significant interference when challenged with extraordinarily high levels of potentially cross reacting drugs. Results obtained with the EMIT assay correlated well with GLC data and rank it as an attractive alternative to many of the existing procedures now being used.

  17. Prediction of broadband ground-motion time histories: Hybrid low/high-frequency method with correlated random source parameters

    Science.gov (United States)

    Liu, P.; Archuleta, R.J.; Hartzell, S.H.

    2006-01-01

    We present a new method for calculating broadband time histories of ground motion based on a hybrid low-frequency/high-frequency approach with correlated source parameters. Using a finite-difference method we calculate low- frequency synthetics (3D velocity structure. We also compute broadband synthetics in a 1D velocity model using a frequency-wavenumber method. The low frequencies from the 3D calculation are combined with the high frequencies from the 1D calculation by using matched filtering at a crossover frequency of 1 Hz. The source description, common to both the 1D and 3D synthetics, is based on correlated random distributions for the slip amplitude, rupture velocity, and rise time on the fault. This source description allows for the specification of source parameters independent of any a priori inversion results. In our broadband modeling we include correlation between slip amplitude, rupture velocity, and rise time, as suggested by dynamic fault modeling. The method of using correlated random source parameters is flexible and can be easily modified to adjust to our changing understanding of earthquake ruptures. A realistic attenuation model is common to both the 3D and 1D calculations that form the low- and high-frequency components of the broadband synthetics. The value of Q is a function of the local shear-wave velocity. To produce more accurate high-frequency amplitudes and durations, the 1D synthetics are corrected with a randomized, frequency-dependent radiation pattern. The 1D synthetics are further corrected for local site and nonlinear soil effects by using a 1D nonlinear propagation code and generic velocity structure appropriate for the site’s National Earthquake Hazards Reduction Program (NEHRP) site classification. The entire procedure is validated by comparison with the 1994 Northridge, California, strong ground motion data set. The bias and error found here for response spectral acceleration are similar to the best results that have been

  18. Dynamical Behaviors between the PM10 and the meteorological factor using the detrended cross-correlation analysis method

    Science.gov (United States)

    Kim, Kyungsik; Lee, Dong-In

    2013-04-01

    There is considerable interest in cross-correlations in collective modes of real data from atmospheric geophysics, seismology, finance, physiology, genomics, and nanodevices. If two systems interact mutually, that interaction gives rise to collective modes. This phenomenon is able to be analyzed using the cross-correlation of traditional methods, random matrix theory, and the detrended cross-correlation analysis method. The detrended cross-correlation analysis method was used in the past to analyze several models such as autoregressive fractionally integrated moving average processes, stock prices and their trading volumes, and taxi accidents. Particulate matter is composed of the organic and inorganic mixtures such as the natural sea salt, soil particle, vehicles exhaust, construction dust, and soot. The PM10 is known as the particle with the aerodynamic diameter (less than 10 microns) that is able to enter the human respiratory system. The PM10 concentration has an effect on the climate change by causing an unbalance of the global radiative equilibrium through the direct effect that blocks the stoma of plants and cuts off the solar radiation, different from the indirect effect that changes the optical property of clouds, cloudiness, and lifetime of clouds. Various factors contribute to the degree of the PM10 concentration. Notable among these are the land-use types, surface vegetation coverage, as well as meteorological factors. In this study, we analyze and simulate cross-correlations in time scales between the PM10 concentration and the meteorological factor (among temperature, wind speed and humidity) using the detrended cross-correlation analysis method through the removal of specific trends at eight cities in the Korean peninsula. We divide time series data into Asian dust events and non-Asian dust events to analyze the change of meteorological factors on the fluctuation of PM10 the concentration during Asian dust events. In particular, our result is

  19. Kinetic theory of correlated fluids: from dynamic density functional to Lattice Boltzmann methods.

    Science.gov (United States)

    Marconi, Umberto Marini Bettolo; Melchionna, Simone

    2009-07-07

    Using methods of kinetic theory and liquid state theory we propose a description of the nonequilibrium behavior of molecular fluids, which takes into account their microscopic structure and thermodynamic properties. The present work represents an alternative to the recent dynamic density functional theory, which can only deal with colloidal fluids and is not apt to describe the hydrodynamic behavior of a molecular fluid. The method is based on a suitable modification of the Boltzmann transport equation for the phase space distribution and provides a detailed description of the local structure of the fluid and its transport coefficients. Finally, we propose a practical scheme to solve numerically and efficiently the resulting kinetic equation by employing a discretization procedure analogous to the one used in the Lattice Boltzmann method.

  20. CORRELATIONS BETWEEN CONTEMPORARY METHODS IN THE DIAGNOSIS OF CHLAMYDIA TRACHOMATIS UROGENITAL INFECTIONS.

    Directory of Open Access Journals (Sweden)

    Ilko Bakardzhiev

    2011-10-01

    Full Text Available The subject of this study were 486 outpatients between the ages of 17 and 62, diagnosed with urethritis, epidydimitis, prostatitis, cervicitis, endocervicitis, pelvic inflammatory disease and sterility. The following tests were used to make the diagnosis of Chlamydia trachomatis: Enzyme Immunoassay (EIA, Enzyme-Linked Fluorescent Assay (ELFA, Polymerase Chain Reaction DNA amplification for Chlamydia Trachomatis, Neisseria Gonorrhoeae, Mycoplasma Genitalium and Ureaplasma Urealyiticum. Comparison PCR and EIA showed statistically significant difference between the positive results obtained by the two methods (p0,1. EIA is a method that gives a higher percentage of nonspecific positive reactions, while the results obtained from ELFA are much closer to the ones obtained by PCR. According to contemporary evidence based medicine, the developmet of unified standard methods for diagnosis and evaluation is of vital importance, not only for the patient and the treating physician but also concerns for the healthcare system, the general public and the pharmaceutical companies as well.

  1. Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study

    DEFF Research Database (Denmark)

    van Straaten, EC; Fazekas, F; Rostrup, Egill;

    2006-01-01

    between groups with and without symptoms. METHODS: We used data of 618 independently living elderly with WMH collected in the Leukoaraiosis And DISability (LADIS) study. Subjects with and without symptoms of depression, gait disturbances, urinary incontinence, and memory decline were compared with respect......BACKGROUND AND PURPOSE: White matter hyperintensities (WMH) are associated with decline in cognition, gait, mood, and urinary continence. Associations may depend on the method used for measuring WMH. We investigated the ability of different WMH scoring methods to detect differences in WMH load...... and Mann-Whitney tests. In addition, the punctate and confluent lesion type with comparable WMH volume were compared with respect to the clinical data using Student t test and chi2 test. Direct comparison of visual ratings with volumetry was done using curve fitting. RESULTS: Visual and volumetric...

  2. Validation of Shape Context Based Image Registration Method Using Digital Image Correlation Measurement on a Rat Stomach

    DEFF Research Database (Denmark)

    Liao, Donghua; Wang, P; Zhao, Jingbo

    2014-01-01

    needs to be further verified by using a feature tracking measurement. Hence, the aim of this study was to verify the SC method-based calculation by using digital image correlation (DIC) measurement on a rat stomach. The rat stomach exposed to distension pressures 0.0, 0.2, 0.4, and 0.6 kPa were studied...... and quantitative agreement on the surfaces with small dissimilarity and small sample count difference between the reference surface and the target surface. In conclusion, this is the first study to validate the 3D SC-based image registration method by using unique tracking features measurement. The developed...

  3. Calculation of space localized properties in correlated quantum Monte Carlo methods with reweighting: the nonlocality of statistical uncertainties.

    Science.gov (United States)

    Assaraf, Roland; Domin, Dominik

    2014-03-01

    We study the efficiency of quantum Monte Carlo (QMC) methods in computing space localized ground state properties (properties which do not depend on distant degrees of freedom) as a function of the system size N. We prove that for the commonly used correlated sampling with reweighting method, the statistical fluctuations σ2(N) do not obey the locality property. σ2(N) grow at least linearly with N and with a slope that is related to the fluctuations of the reweighting factors. We provide numerical illustrations of these tendencies in the form of QMC calculations on linear chains of hydrogen atoms.

  4. Influence Of Sample Preparation Method On Isothermal Studies During Compatibility Screening Of Ofloxacin; Correlation With DSC Data

    Directory of Open Access Journals (Sweden)

    M. Misra, A. K. MISRA,, G. M. Panpalia

    2011-05-01

    Full Text Available Objectives: The compatibility of ofloxacin with somecommonly used diluents has been investigated usingisothermal stability studies (IST to allow relative ranking.Materials and Methods: The samples were prepared usingthree methods namely physical admixtures (with 5% addedmoisture, slugging and kneading in order to evaluate theeffect of mechanical treatment on the physicochemical stabilityof drug. To further verify the results of IST fresh binarymixtures were subjected to thermal analysis and an attemptwas made to correlate the results obtained from the twostudies.Results: The results from both DSC and IST revealed thatofloxacin was compatible with all the diluents used in thestudy. Among the three methods of sample preparation usedfor the study, the extent of degradation was more or less samein all the three methods indicating least influence of method ofsample preparation on the results of IST.Conclusions: From the study it was concluded that a betterco-correlation could have been obtained had ofloxacin beenmore unstable with few of the excipients than rest, used in thestudy. This way the extent of degradation would bedistinguishing enough to rank the excipients in decreasingorder of stability.

  5. Approach to the Correlation Discovery of Chinese Linguistic Parameters Based on Bayesian Method

    Institute of Scientific and Technical Information of China (English)

    WANG Wei(王玮); CAI LianHong(蔡莲红)

    2003-01-01

    Bayesian approach is an important method in statistics. The Bayesian belief network is a powerful knowledge representation and reasoning tool under the conditions of uncertainty.It is a graphics model that encodes probabilistic relationships among variables of interest. In this paper, an approach to Bayesian network construction is given for discovering the Chinese linguistic parameter relationship in the corpus.

  6. Image correlation based method for the analysis of collagen fibers patterns

    Science.gov (United States)

    Rosa, Ramon G. T.; Pratavieira, Sebastião.; Kurachi, Cristina

    2015-06-01

    The collagen fibers are one of the most important structural proteins in skin, being responsible for its strength and flexibility. It is known that their properties, like fibers density, ordination and mean diameter can be affected by several skin conditions, what makes these properties a good parameter to be used on the diagnosis and evaluation of skin aging, cancer, healing, among other conditions. There is, however, a need for methods capable of analyzing quantitatively the organization patterns of these fibers. To address this need, we developed a method based on the autocorrelation function of the images that allows the construction of vector field plots of the fibers directions and does not require any kind of curve fitting or optimization. The analyzed images were obtained through Second Harmonic Generation Imaging Microscopy. This paper presents a concise review on the autocorrelation function and some of its applications to image processing, details the developed method and the results obtained through the analysis of hystopathological slides of landrace porcine skin. The method has high accuracy on the determination of the fibers direction and presents high performance. We look forward to perform further studies keeping track of different skin conditions over time.

  7. Correlation of Condylar Guidance Determined by Panoramic Radiographs to One Determined by Conventional Methods

    Science.gov (United States)

    Godavarthi, A Sowjanya; Sajjan, M C Suresh; Raju, A V Rama; Rajeshkumar, P; Premalatha, Averneni; Chava, Narayana

    2015-01-01

    Background: To evaluate the feasibility of using panoramic radiographs as an alternative to an interocclusal recording method for determining the condylar guidance in dentate and edentulous conditions. Materials and Methods: 20 dentulous individuals with an age range of 20-30 years and 20 edentulous patients of 40-65 years were selected. An interocclusal bite registration was done in protrusive position for all the subjects. Orthopantomographs were made for all patients in open mouth position. Hanau articulator was modified to record the angulations to the accuracy of 1°. Tracing of glenoid fossa on radiograph was done to measure the condylar guidance angles. Readings were recorded and analyzed by Freidman’s test and t-test. Results: Condylar guidance values obtained by the interocclusal method and radiographic method in dentate individuals on the right side and left side 40.55°, and 37.1°, and 40.15°, and 34.75°, respectively. In the edentulous individuals, the values on the right side and left side was 36.7° and 36.1° and 35.95° and 33.6,° respectively. The difference was statistically significant (P = < 0.001) in dentate group and was not statistically significant (P = 0.6493) in edentulous group. Conclusion: Panoramic radiograph can be used as an alternative to interocclusal technique only in edentulous patients. Further studies comparing panoramic radiograph to jaw tracking devices would substantiate the results of this study. PMID:26464554

  8. Modeling dental composite shrinkage by digital image correlation and finite element methods

    Science.gov (United States)

    Chen, Terry Yuan-Fang; Huang, Pin-Sheng; Chuang, Shu-Fen

    2014-10-01

    Dental composites are light-curable resin-based materials with an inherent defect of polymerization shrinkage which may cause tooth deflection and debonding of restorations. This study aimed to combine digital image correlation (DIC) and finite element analysis (FEA) to model the shrinkage behaviors under different light curing regimens. Extracted human molars were prepared with proximal cavities for composite restorations, and then divided into three groups to receive different light curing protocols: regular intensity, low intensity, and step-curing consisting of low and high intensities. For each tooth, the composite fillings were consecutively placed under both unbonded and bonded conditions. At first, the shrinkage of the unbonded restorations was analyzed by DIC and adopted as the setting of FEA. The simulated shrinkage behaviors obtained from FEA were further validated by the measurements in the bonded cases. The results showed that different light curing regimens affected the shrinkage in unbonded restorations, with regular intensity showing the greatest shrinkage strain on the top surface. The shrinkage centers in the bonded cases were located closer to the cavity floor than those in the unbonded cases, and were less affected by curing regimens. The FEA results showed that the stress was modulated by the accumulated light energy density, while step-curing may alleviate the tensile stress along the cavity walls. In this study, DIC provides a complete description of the polymerization shrinkage behaviors of dental composites, which may facilitate the stress analysis in the numerical investigation.

  9. Topology of the correlation networks among major currencies using hierarchical structure methods

    Science.gov (United States)

    Keskin, Mustafa; Deviren, Bayram; Kocakaplan, Yusuf

    2011-02-01

    We studied the topology of correlation networks among 34 major currencies using the concept of a minimal spanning tree and hierarchical tree for the full years of 2007-2008 when major economic turbulence occurred. We used the USD (US Dollar) and the TL (Turkish Lira) as numeraires in which the USD was the major currency and the TL was the minor currency. We derived a hierarchical organization and constructed minimal spanning trees (MSTs) and hierarchical trees (HTs) for the full years of 2007, 2008 and for the 2007-2008 period. We performed a technique to associate a value of reliability to the links of MSTs and HTs by using bootstrap replicas of data. We also used the average linkage cluster analysis for obtaining the hierarchical trees in the case of the TL as the numeraire. These trees are useful tools for understanding and detecting the global structure, taxonomy and hierarchy in financial data. We illustrated how the minimal spanning trees and their related hierarchical trees developed over a period of time. From these trees we identified different clusters of currencies according to their proximity and economic ties. The clustered structure of the currencies and the key currency in each cluster were obtained and we found that the clusters matched nicely with the geographical regions of corresponding countries in the world such as Asia or Europe. As expected the key currencies were generally those showing major economic activity.

  10. Stress-wave induced fracture of unidirectional composites: an experimental study using digital image correlation method

    Science.gov (United States)

    Lee, Dongyeon; Tippur, Hareesh V.

    2010-03-01

    In this work, fracture behavior of unidirectional graphite/epoxy composite materials is optically investigated. Single-edge notched coupons are studied under geometrically symmetric impact loading. The notch orientation parallel to or at an angle relative to the fiber orientation is considered to produce mode-I as well as mixed-mode fracture. Stress-wave induced crack initiation and rapid crack growth events are studied using a digital correlation technique and high-speed photography. Surface deformations histories in the crack-tip vicinity are obtained by analyzing decorated speckle recordings. Measured deformation fields are used to extract fracture parameters and examine the effect of fiber orientation on crack initiation and growth behaviors. The maximum crack speed observed is the highest for mode-I dominant conditions and decreases with increasing fiber orientation angle. With increasing fiber orientation angle, crack takes longer to attain the maximum speed upon initiation. The crack initiation toughness values decrease with increasing degree-of-anisotropy.

  11. Functional cine MR imaging for the detection and mapping of intraabdominal adhesions: method and surgical correlation

    Energy Technology Data Exchange (ETDEWEB)

    Buhmann-Kirchhoff, Sonja; Reiser, Maximilian; Lienemann, Andreas [University Hospital Grosshadern, Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Munich (Germany); Lang, Reinhold; Steitz, Heinrich O.; Jauch, Karl W. [University Hospital Munich-Grosshadern, Department of Surgery, Munich (Germany); Kirchhoff, Chlodwig [University Hospital Munich-Innenstadt, Department of Surgery, Munich (Germany)

    2008-06-15

    The purpose of this study was to evaluate the presence and localization of intraabdominal adhesions using functional cine magnetic resonance imaging (MRI) and to correlate the MR findings with intraoperative results. In a retrospective study, patients who had undergone previous abdominal surgery with suspected intraabdominal adhesions were examined. A true fast imaging with steady state precession sequence in transverse/sagittal orientation was used for a section-by-section dynamic depiction of visceral slide on a 1.5-Tesla system. After MRI, all patients underwent anew surgery. A nine-segment abdominal map was used to document the location and type of the adhesions. The intraoperative results were taken as standard of reference. Ninety patients were enrolled. During surgery 71 adhesions were detected, MRI depicted 68 intraabdominal adhesions. The most common type of adhesion in MRI was found between the anterior abdominal wall and small bowel loops (n = 22, 32.5%) and between small bowel loops and pelvic organs (n = 14, 20.6%). Comparing MRI with the intraoperative findings, sensitivity varied between 31 and 75% with a varying specificity between 65 and 92% in the different segments leading to an overall MRI accuracy of 89%. Functional cine MRI proved to be a useful examination technique for the identification of intraabdominal adhesions in patients with acute or chronic pain and corresponding clinical findings providing accurate results. However, no differentiation for symptomatic versus asymptomatic adhesions is possible. (orig.)

  12. Estimation of resting-state functional connectivity using random subspace based partial correlation: a novel method for reducing global artifacts.

    Science.gov (United States)

    Chen, Tianwen; Ryali, Srikanth; Qin, Shaozheng; Menon, Vinod

    2013-11-15

    Intrinsic functional connectivity analysis using resting-state functional magnetic resonance imaging (rsfMRI) has become a powerful tool for examining brain functional organization. Global artifacts such as physiological noise pose a significant problem in estimation of intrinsic functional connectivity. Here we develop and test a novel random subspace method for functional connectivity (RSMFC) that effectively removes global artifacts in rsfMRI data. RSMFC estimates the partial correlation between a seed region and each target brain voxel using multiple subsets of voxels sampled randomly across the whole brain. We evaluated RSMFC on both simulated and experimental rsfMRI data and compared its performance with standard methods that rely on global mean regression (GSReg) which are widely used to remove global artifacts. Using extensive simulations we demonstrate that RSMFC is effective in removing global artifacts in rsfMRI data. Critically, using a novel simulated dataset we demonstrate that, unlike GSReg, RSMFC does not artificially introduce anti-correlations between inherently uncorrelated networks, a result of paramount importance for reliably estimating functional connectivity. Furthermore, we show that the overall sensitivity, specificity and accuracy of RSMFC are superior to GSReg. Analysis of posterior cingulate cortex connectivity in experimental rsfMRI data from 22 healthy adults revealed strong functional connectivity in the default mode network, including more reliable identification of connectivity with left and right medial temporal lobe regions that were missed by GSReg. Notably, compared to GSReg, negative correlations with lateral fronto-parietal regions were significantly weaker in RSMFC. Our results suggest that RSMFC is an effective method for minimizing the effects of global artifacts and artificial negative correlations, while accurately recovering intrinsic functional brain networks.

  13. Method for Caution Values Calculation of Dissolved Gases in Transformers Based on Statistical Distribution and Correlation Analysis

    Institute of Scientific and Technical Information of China (English)

    WANG Xuelei; LI Qingmin; LI Chengrong; YANG Rui; GAO Shuguo

    2013-01-01

    Before diagnosed by DGA (dissolved gas analysis) methods,gas caution values,which index the level of gas formation,must be used to evaluate the possibility of incipient faults to reduce the misdiagnosis in the normal state.However,the calculation of these values is now only based on cumulative percentile method without taking into account operating conditions.To overcome this disadvantage,a new approach to calculate the transformer caution values is presented.This approach is based on statistical distribution and correlation analysis,and it takes the individual variation and fluctuation caused by intemal and external factors into consideration.Then 6550 transformer DGA data collected from North China Power Grid are analyzed in this paper.The results show that the volume fraction of TH (total hydrocarbon)approximately obeys normal distribution when the 3-sigma rule is used to calculate its caution value.The volume fraction of CO has a strong positive correlation with oil temperature.For H2,the negative correlation with oil temperature is significant when the volume fraction is not very low.The caution value curves for CO and H2 are obtained by regression analyses.Thus,the gas caution values/curves obtained using the new method are not always constant,but vary with oil temperature,which is an advantage of the proposed method compared with cumulative percentile method.The variation of gas caution values/curves also reflects the influence of the external factors,for instance,varying with monitoring time ensures that the gas caution values are always consistent with operating status.

  14. Measuring the galaxy power spectrum and scale-scale correlations with multiresolution-decomposed covariance; 1, method

    CERN Document Server

    Fang, L Z; Fang, Li-Zhi; Feng, Long-Long

    2000-01-01

    We present a method of measuring galaxy power spectrum based on the multiresolution analysis of the discrete wavelet transformation (DWT). Since the DWT representation has strong capability of suppressing the off-diagonal components of the covariance for selfsimilar clustering, the DWT covariance for popular models of the cold dark matter cosmogony generally is diagonal, or $j$(scale)-diagonal in the scale range, in which the second scale-scale correlations are weak. In this range, the DWT covariance gives a lossless estimation of the power spectrum, which is equal to the corresponding Fourier power spectrum banded with a logarithmical scaling. In the scale range, in which the scale-scale correlation is significant, the accuracy of a power spectrum detection depends on the scale-scale or band-band correlations. This is, for a precision measurements of the power spectrum, a measurement of the scale-scale or band-band correlations is needed. We show that the DWT covariance can be employed to measuring both the ...

  15. Drug release profiles of modified MCM-41 with superparamagnetic behavior correlated with the employed synthesis method.

    Science.gov (United States)

    Cuello, Natalia I; Elías, Verónica R; Mendieta, Silvia N; Longhi, Marcela; Crivello, Mónica E; Oliva, Marcos I; Eimer, Griselda A

    2017-09-01

    Mesoporous materials with superparamagnetic properties were successfully synthesized by two different methods: direct incorporation (DI) and wet impregnation (WI). The synthetized solids were evaluated as host of drugs for delivery systems and their physicochemical properties were characterized by XRD, ICP, N2 adsorption-desorption, spectroscopies of UV-Vis DR, FT-IR and their magnetic properties were measured. Indomethacin (IND) was incorporated into the materials and the kinetic of the release profiles was studied by applying the Pepas and Sahlin model. In this sense, materials modified by DI, particularly that with hydrothermal treatment, showed the higher adsorption capacity and slower release rate. This behavior could be associated to the synthesis method used that allowed a high percentage of silanol groups available in the solids surface, which can interact with the IND molecule. This feature coupled with the superparamagnetic behavior; make these materials very interesting for drug delivery systems. Copyright © 2017. Published by Elsevier B.V.

  16. Numerical simulation of correlation method calculating the transverse component of the wind speed on basis of the measurements on the Shack-Hartmann sensor

    Science.gov (United States)

    Goleneva, N. V.; Lavrinov, V. V.; Lavrinova, L. N.

    2014-11-01

    According to data obtained at atmospheric path, was tested an algorithm for calculating the transverse component of the wind speed by correlation analysis of measurements on the Shack-Hartmann wavefront sensor. The correlation method is based on the hypothesis of "frozen" turbulence. Calculated correlation values are the coefficients of the linear correlation between the displacements of the coordinates of the centroids. To automate the algorithm for calculating the transverse component of the wind speed were created the following programming techniques: the moving average method, the gradient descent method, the method of calculation of derivatives.

  17. Measurement of multi-particle azimuthal correlations with the subevent cumulant method with the ATLAS detector

    CERN Document Server

    Zhou, Mingliang; The ATLAS collaboration

    2017-01-01

    The measurement of four-particle cumulant and anisotropic elliptic flow coefficient for the second harmonic, $c_{2}\\{4\\}$ and $v_{2}\\{4\\}$, are presented using $pp$ data at $\\sqrt{s}=5.02$ and $\\sqrt{s}=13$ TeV, and $p+$Pb data at $\\sqrt{s_{\\text{NN}}}=5.02$ TeV. These measurements aim to assess collective nature of multi-particle production. While collectivity is well established in $p$+Pb and Pb+Pb collisions, because of larger non-flow contributions, its evidence in $pp$ collisions is contested. The values of $c_{2}\\{4\\}$ are calculated using the standard cumulant method and recently proposed two and three subevent methods, which can further suppress the non-flow contributions in small systems. In these collisions systems, the three subevent method gives a negative $c_{2}\\{4\\}$, and thus a well-defined $v_{2}\\{4\\}$. The magnitude of $c_{2}\\{4\\}$ is found to be nearly independent of $\\langle N_{\\text{ch}} \\rangle$ and third harmonic $c_{3}\\{4\\}$ is consistent with 0. $v_{2}\\{4\\}$ is found to be smaller than...

  18. Chromatographic Characterization and Method Development for Determination of Levetiracetam in Saliva: Application to Correlation with Plasma Levels

    Directory of Open Access Journals (Sweden)

    Imad I. Hamdan

    2017-01-01

    Full Text Available Levetiracetam (LVT is a widely used antiepileptic drug (AED. A less invasive sampling method for therapeutic drug monitoring (TDM would be very useful particularly for children. Saliva has been shown as an adequate sample for TDM of some AEDs. Due to the high hydrophilicity of LVT its separation on common stationary phases is quite a challenge so that previous methods for determination of LVT in saliva employed either gradient high performance liquid chromatographic (HPLC system or mass spectrometer as a detector. In this study the retention behavior of LVT on some common stationary phases was examined, with C8 being the most retentive. A simple isocratic HPLC method that is based on simple protein precipitation was developed and validated for the determination of LVT in saliva. The method was applied to a sample group of epileptic children for the purpose of assessing potential correlation with plasma LVT levels and to investigate patient’s compliance. The results confirmed a reasonable correlation between plasma and salivary levels of LVT (R = 0.9 which supports the use of saliva for TDM of LVT. The study also revealed a significant percentage of epileptic patients having LVT levels below the estimated therapeutic range.

  19. A Correlation Based Method for Discriminating Inrush Current from Short Circuit Current Using Wavelet Transform in Power Transformer Differential Protection

    Directory of Open Access Journals (Sweden)

    M. Rasoulpoor

    2013-09-01

    Full Text Available This paper presents a new approach for power transformer differential protection. The Wavelet Transform is applied to discriminate between inrush currents and internal fault currents in power transformers. Discrete wavelet transform decomposes the current signal into sub-bands that give more information about the properties of the signals in different frequency bands. Also, this transform is used to investigate the energy distribution of the signal on the different time and frequency scales. Recognition method is based on the correlation factors between energy percentage vectors of the Wavelet coefficients. Discrete Wavelet transform is used for decomposing the current signals to different frequency coefficients. After that, by constituting the energy percentage vectors of wavelet transform coefficients and calculating the correlation factors between these vectors, it is possible to form a recognition criterion to distinguish between inrush and internal fault current in the proposed method. The proposed algorithm is tested for several conditions by simulated inrush and internal fault currents. Simulation of current signals is performed using electromagnetic transient program PSCAD/EMTDC software that is a powerful program for the investigation of transient signals. Simulation results show that the proposed scheme accurately identifies inrush and fault currents in the distance of the power transformer protection in less than quarter of power frequency cycle. Also, beside the sensitivity and high reliability, the proposed method has low computation content and unlike the common methods does not require to determine the threshold for each new power system.

  20. Ultrasound thermal mapping based on a hybrid method combining cross-correlation and zero-crossing tracking.

    Science.gov (United States)

    Huang, Chang-Wei; Lien, Der-Hsien; Chen, Ben-Ting; Shieh, Jay; Tsui, Po-Hsiang; Chen, Chuin-Shan; Chen, Wen-Shiang

    2013-08-01

    A hybrid method for estimating temperature with spatial mapping using diagnostic ultrasound, based on detection of echo shifts from tissue undergoing thermal treatment, is proposed. Cross-correlation and zero-crossing tracking are two conventional algorithms used for detecting echo shifts, but their practical applications are limited. The proposed hybrid method combines the advantages of both algorithms with improved accuracy in temperature estimation. In vitro experiments were performed on porcine muscle for preliminary validation and temperature calibration. In addition, thermal mapping of rabbit thigh muscle in vivo during high-intensity focused ultrasound heating was conducted. Results from the in vitro experiments indicated that the difference between the estimated temperature change by the proposed hybrid method and the actual temperature change measured by the thermocouple was generally less than 1 °C when the increase in temperature due to heating was less than 10 °C. For the in vivo study, the area predicted to experience the highest temperature coincided well with the focal point of the high-intensity focused ultrasound transducer. The computational efficiency of the hybrid algorithm was similar to that of the fast cross-correlation algorithm, but with an improved accuracy. The proposed hybrid method could provide an alternative means for non-invasive monitoring of limited temperature changes during hyperthermia therapy.

  1. Using deep learning to investigate the neuroimaging correlates of psychiatric and neurological disorders: Methods and applications.

    Science.gov (United States)

    Vieira, Sandra; Pinaya, Walter H L; Mechelli, Andrea

    2017-03-01

    Deep learning (DL) is a family of machine learning methods that has gained considerable attention in the scientific community, breaking benchmark records in areas such as speech and visual recognition. DL differs from conventional machine learning methods by virtue of its ability to learn the optimal representation from the raw data through consecutive nonlinear transformations, achieving increasingly higher levels of abstraction and complexity. Given its ability to detect abstract and complex patterns, DL has been applied in neuroimaging studies of psychiatric and neurological disorders, which are characterised by subtle and diffuse alterations. Here we introduce the underlying concepts of DL and review studies that have used this approach to classify brain-based disorders. The results of these studies indicate that DL could be a powerful tool in the current search for biomarkers of psychiatric and neurologic disease. We conclude our review by discussing the main promises and challenges of using DL to elucidate brain-based disorders, as well as possible directions for future research.

  2. Extraction of ionization spectra from correlated wave functions: a comparison between different methods

    CERN Document Server

    Argenti, Luca; Feist, Johannes; Nagele, Stefan; Liertzer, Matthias; Persson, Emil; Burgdörfer, Joachim; Lindroth, Eva

    2013-01-01

    We compare three techniques to extract partial photoelectron spectra from the wave packet resulting from the integration on a finite-element discrete variable representation basis of the time-dependent Schr\\"odinger equation for an helium atom subject to an ultra-short XUV pulse. These techniques are: projection on products of hydrogenic bound and continuum states, projection onto multi-channel scattering states computed in a B-spline close-coupling basis, and a technique based on exterior complex scaling (ECS) [Palacios \\emph{et al}, Phys. Rev. A {\\bf 76}, 043420 (2007)] implemented in the same basis used for the time propagation. These methods allow to monitor the population of continuum states in wave packets created with ultrashort pulses in different regimes. The first method works well at the energies where the ionization continuum is unstructured while it becomes inefficient close to threshold openings due to the presence of long-lived metastable states or of vanishingly slow photofragments. The agreem...

  3. New method for estimation of fluence complexity in IMRT fields and correlation with gamma analysis

    Science.gov (United States)

    Hanušová, T.; Vondráček, V.; Badraoui-Čuprová, K.; Horáková, I.; Koniarová, I.

    2015-01-01

    A new method for estimation of fluence complexity in Intensity Modulated Radiation Therapy (IMRT) fields is proposed. Unlike other previously published works, it is based on portal images calculated by the Portal Dose Calculation algorithm in Eclipse (version 8.6, Varian Medical Systems) in the plane of the EPID aS500 detector (Varian Medical Systems). Fluence complexity is given by the number and the amplitudes of dose gradients in these matrices. Our method is validated using a set of clinical plans where fluence has been smoothed manually so that each plan has a different level of complexity. Fluence complexity calculated with our tool is in accordance with the different levels of smoothing as well as results of gamma analysis, when calculated and measured dose matrices are compared. Thus, it is possible to estimate plan complexity before carrying out the measurement. If appropriate thresholds are determined which would distinguish between acceptably and overly modulated plans, this might save time in the re-planning and re-measuring process.

  4. Evaluation of two diagnostic methods for dengue virus infection and its correlation with thrombocytopenia

    Directory of Open Access Journals (Sweden)

    Tanvi H Panwala

    2016-01-01

    Full Text Available Context: Early definitive diagnosis of dengue virus (DENV infections is essential for the timely management of dengue infections. Aims: The aim of the present study is to compare results of both tests (IgM enzyme-linked immunosorbent assay [ELISA] and nonstructural protein 1 [NS1] and to prove that use of NS1 with IgM ELISA tests improves the dengue laboratory diagnosis. Settings and Design: Tertiary Care Hospital, Gujarat and retrospective cross-sectional study. Subjects and Methods: One thousand three hundred forty-three blood samples were screened from clinically suspected cases of dengue fever reporting at Tertiary Care Hospital, Gujarat from August to November 2014. The samples were divided into three study groups according to the tests performed. In Group 1, 840 samples were subjected for dengue IgM ELISA only. Group 2 comprised 379 samples tested for NS1 antigen (Ag only. Group 3 comprised 124 samples tested by both methods NS1 Ag detection test and IgM ELISA. Statistical Analysis Used: As the study has compared three different groups, Statistical proportion method used and data entry was done in Microsoft office excel version 2010. Results: In Group 1, 145 patients (76.3% found positive between 6 and 10 days of fever. More number of cases (89.4% gave positive reaction in NS1 Ag detection test at <5 days of fever in Group 2. In Group 3, of the forty positive samples, 19 (47% samples gave positive reaction in NS1 Ag detection test and negative in IgM ELISA with <5 days of fever history. Ten patients (25% showed positive IgM ELISA and negative for NS1 at more than 10 days of fever. Eleven patients (27.5% showed both the tests positive between 6 and 10 days of fever. Conclusions: If NS1 Ag detection test used in combination with IgM ELISA on a single serum sample of suspected patients will increase the sensitivity of detection, especially in areas with higher prevalence of secondary DENV infections.

  5. Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study

    DEFF Research Database (Denmark)

    van Straaten, EC; Fazekas, F; Rostrup, Egill;

    2006-01-01

    to WMH load measured qualitatively using 3 widely used visual rating scales (Fazekas, Scheltens, and Age-Related White Matter Changes scales) and quantitatively with a semiautomated volumetric technique and an automatic lesion count. Statistical significance between groups was assessed with the chi2...... between groups with and without symptoms. METHODS: We used data of 618 independently living elderly with WMH collected in the Leukoaraiosis And DISability (LADIS) study. Subjects with and without symptoms of depression, gait disturbances, urinary incontinence, and memory decline were compared with respect...... and Mann-Whitney tests. In addition, the punctate and confluent lesion type with comparable WMH volume were compared with respect to the clinical data using Student t test and chi2 test. Direct comparison of visual ratings with volumetry was done using curve fitting. RESULTS: Visual and volumetric...

  6. Cavity enhanced detection methods for probing the dynamics of spin correlated radical pairs in solution

    Science.gov (United States)

    Neil, Simon R. T.; Maeda, Kiminori; Henbest, Kevin B.; Goez, Martin; Hemmens, Robert; Timmel, Christiane R.; Mackenzie, Stuart R.

    2010-04-01

    Cavity enhanced absorption spectroscopy (CEAS) combined with phase-sensitive detection is employed to study the effects of static magnetic fields on radical recombination reactions. The chemical system comprises the photochemically generated thionine semiquinone radical and a 1,4-diazabicyclo[2.2.2]octane (DABCO) cationic radical in a micellar solution of sodium dodecyl sulphate. Data obtained using the modulated CEAS technique, describing the magnetic field effect (MFE) on reaction yields, are shown to be superior to those obtained using conventional transient absorption (TA) flash photolysis methods typically employed for these measurements. The high sensitivity afforded by modulated CEAS detection is discussed in terms of the new possibilities it offers such as the measurement of magnetic field effects in real biological systems which have hitherto been largely beyond the detection capabilities of existing techniques.

  7. Computational methods and destruction of the Fermi liquid in systems of correlated lattice electrons

    Science.gov (United States)

    Tremblay, A.-M. S.

    2004-03-01

    One of the most striking phenonema observed in the normal state of high-temperature superconductors is the replacement of Landau quasiparticles by a pseudogap in specific regions of the Brillouin zone. It is believed that this phenomenon can be described by the Hubbard Hamiltonian, that models electrons moving on a lattice and interacting through a short-range potential. Because of the theoretical difficulties involved in the solution of the Hubbard model, computational methods have played a key role in proving that the pseudogap phenomenon is indeed a property of the Hubbard model. In so doing, they also allowed physical understanding of the phenomenon. In this talk, the contributions of Cluster Perturbation Theory [1] and auxiliary field Quantum Monte Carlo will be the main focus. At strong coupling, the pseudogap phenomenon will be contrasted with the Mott gap. [2] At weak to intermediate coupling, the importance of antiferromagnetic fluctuations will be demonstrated through a combination of Quantum Monte Carlo and Two-Particle Self-Consistent calculations.[3] More generally, the strengths and limitations of different methods will be discussed along with the role of numerical solutions as benchmarks for non-perturbative approaches. I will also make a few remarks on the Beowulf cluster used for these calculations. Work done in collaboration with D. Sénéchal, B. Kyung and V. Hankevych. [1] D. Sénéchal et al. Phys. Rev. Lett. 84, 522 (2000); Phys. Rev. B 66, 075129 (2002). [2] D. Sénéchal et al. cond-mat/0308625. [3] B. Kyung et al. Phys. Rev. B 68, 174502/1-5 (2003); S. Moukouri, et al. Phys. Rev. B 61, 7887 (2000).

  8. Fast and Reliable Time Delay Estimation of Strong Lens Systems Using Method of Smoothing and Cross-Correlation

    CERN Document Server

    Aghamousa, Amir

    2014-01-01

    The observable time delays between the multiple images of strong lensing systems with time variable sources can provide us with some valuable information to probe the expansion history of the Universe. Estimation of these time delays can be very challenging due to complexities of the observed data where there are seasonal gaps, various noises and systematics such as unknown microlensing effects. In this paper we introduce a novel approach to estimate the time delays for strong lensing systems implementing various statistical methods of data analysis including the method of smoothing and cross-correlation. The method we introduce in this paper has been recently used in TDC0 and TDC1 Strong Lens Time Delay Challenges and has shown its power in reliable and precise estimation of time delays dealing with data with different complexities.

  9. Validation of Shape Context Based Image Registration Method Using Digital Image Correlation Measurement on a Rat Stomach

    DEFF Research Database (Denmark)

    Liao, Donghua; Wang, P; Zhao, Jingbo

    2014-01-01

    Recently we developed analysis for 3D visceral organ deformation by combining the shape context (SC) method with a full-field strain (strain distribution on a whole 3D surface) analysis for calculating distension-induced rat stomach deformation. The surface deformation detected by the SC method...... needs to be further verified by using a feature tracking measurement. Hence, the aim of this study was to verify the SC method-based calculation by using digital image correlation (DIC) measurement on a rat stomach. The rat stomach exposed to distension pressures 0.0, 0.2, 0.4, and 0.6 kPa were studied...... using both 3D DIC system and SC-based image registration calculation. Three different surface sample counts between the reference and the target surfaces were usedto gauge the effect of the surface sample counts on the calculation. Each pair of the surface points between the DIC measured target surface...

  10. Communication: Multipole approximations of distant pair energies in local correlation methods with pair natural orbitals

    Science.gov (United States)

    Werner, Hans-Joachim

    2016-11-01

    The accuracy of multipole approximations for distant pair energies in local second-order Møller-Plesset perturbation theory (LMP2) as introduced by Hetzer et al. [Chem. Phys. Lett. 290, 143 (1998)] is investigated for three chemical reactions involving molecules with up to 92 atoms. Various iterative and non-iterative approaches are compared, using different energy thresholds for distant pair selection. It is demonstrated that the simple non-iterative dipole-dipole approximation, which has been used in several recent pair natural orbitals (PNO)-LMP2 and PNO-LCCSD (local coupled-cluster with singles and doubles) methods, may underestimate the distant pair energies by up to 50% and can lead to significant errors in relative energies, unless very tight thresholds are used. The accuracy can be much improved by including higher multipole orders and by optimizing the distant pair amplitudes iteratively along with all other amplitudes. A new approach is presented in which very small special PNO domains for distant pairs are used in the iterative approach. This reduces the number of distant pair amplitudes by 3 orders of magnitude and keeps the additional computational effort for the iterative optimization of distant pair amplitudes minimal.

  11. DATA MODELING METHOD BASED ON PARTIAL LEAST SQUARE REGRESSION AND APPLICATION IN CORRELATION ANALYSIS OF THE STATOR BARS CONDITION PARAMETERS

    Institute of Scientific and Technical Information of China (English)

    李锐华; 高乃奎; 谢恒堃; 史维祥

    2004-01-01

    Objective To investigate various data message of the stator bars condition parameters under the condition that only a few samples are available, especially about correlation information between the nondestructive parameters and residual breakdown voltage of the stator bars. Methods Artificial stator bars is designed to simulate the generator bars. The partial didcharge( PD) and dielectric loss experiments are performed in order to obtain the nondestructive parameters, and the residual breakdown voltage acquired by AC damage experiment. In order to eliminate the dimension effect on measurement data, raw data is preprocessed by centered-compress. Based on the idea of extracting principal components, a partial least square (PLS) method is applied to screen and synthesize correlation information between the nondestructive parameters and residual breakdown voltage easily. Moreover, various data message about condition parameters are also discussed. Results Graphical analysis function of PLS is easily to understand various data message of the stator bars condition parameters. The analysis Results are consistent with result of aging testing. Conclusion The method can select and extract PLS components of condition parameters from sample data, and the problems of less samples and multicollinearity are solved effectively in regression analysis.

  12. [Ammonia gas concentration and velocity measurement using tunable diode laser absorption spectroscopy and optical signal cross-correlation method].

    Science.gov (United States)

    Zhang, Chun-Xiao; Wang, Fei; Li, Ning; Yan, Jian-Hua; Chi, Yong; Cen, Ke-Fa

    2009-10-01

    Simultaneous online measurement of gas concentration and velocity can be realized by tunable diode laser absorption spectroscopy (TDLAS) technique and optical signal cross-correlation method. The fundamental and relative factors of gas concentration and velocity measurement are described in the present paper. The spectral lines of NH3 used for gas sensing at communication band in near infrared range were selected and analyzed by the calculation based on the HITRAN database. In the verification experiment, NH3 and N2 were mixed by two mass flow meters and sent to flow through the quartz tube 0. 016 m in inner diameter and 1 m in length at normal temperature and pressure. The spectral line located at 6,548.7 cm(-1) was scanned at high frequency by the diode laser of 15 MHz linewidth and 1 cm' tunable range with no mode hoppings. The instantaneous NH3 absorbance was obtained using direct absorption method and the gas concentration was calculated. At the same time, the non-intrusive optical absorption signal cross-correlation method was utilized to obtain two concentration signals from two adjacent detectors mounted along the gas tube. The corresponding transit time of gas passing through the detectors was calculated by cross-correlation algorithm, and the average gas velocity was inferred according to the distance between the two detectors and the transit time. The relative errors were less than 7% for the gas concentration measurement, and less than 10% for the gas velocity measurement. Experimental results were proved to be of high precision and good repeatability in the lab. The feature of fast response and capacity immune to the in situ disturbance would lead to a potential in industry application for the real time measurement and control of gas pollutant emission in the future.

  13. [Evaluation methods in the work/stress correlations in law enforcement].

    Science.gov (United States)

    Magnavital, Nicola; Garbarino, Sergio; Siegrist, Johannes

    2014-01-01

    Stress in police: assessment methods. Police work is unanimously considered stressful. Prevention of stress in police is of the utmost importance, as a distressed officer could be hazardous for third parties. There is scientific evidence that the relationship between occupational stressors and their psychological and physical consequences can be described by Karasek's demand-control-support (DCS) model and the effort / reward imbalance (ERI) model of Siegrist. This study summarizes the results of surveys conducted using the DCS and ERI questionnaires.on police officers from the VI Mobile Unit of Genoa who were engaged in public order management at the G8 summit in L'Aquila in 2009. In spite of the high alert due to expected threats to public order during the G8 meeting, police officers were not affected by "distress". When the policemen were compared to other categories of workers, their stress levels were in the lowest range. In most cases, the personality profile of these workers did not differ substantially from that of the general population. There was an association between personality and stress response. The levels of perceived stress were significantly associated with absence from work. The prevalence of mental disorders in police officers was significantly lower than that of the general population. Occupational stress was associated with indicators of depression, anxiety and burnout. The DCS and ERI models yielded complementary results and proved to be effective in assessing the effects of stress in law enforcement. The extent of perceived stress does not directly depend on external events, but on the way in which these are handled: routine work may be more stressful than a single critical event. Special police forces are particularly resilient to stress, partly due to the characteristics and personality of individual officers, but mainly on account of their training. Occupational stress is associated with a lower level of psychological well-being and an

  14. Correlation between chronological age and third molar developmental stages in an Iranian population (Demirjian method).

    Science.gov (United States)

    Khosronejad, Aria; Navabi, Manijeh; Sakhdari, Shirin; Rakhshan, Vahid

    2017-01-01

    Third molar development is the only available tool for estimating the age of individuals after puberty. Since this tooth has very high interethnic variability, formulas calculated to estimate the age from its development stages cannot be generalized to other populations and should be adjusted for each region. Therefore, this study was conducted to evaluate this method in a sample of Tehran individuals for the first time, and also to compare the development of third molars across sexes and arches, and to estimate cutoff developmental stages for legal minor/major identification. A total of 150 dental patients aged between 15 and 25 years old were prospectively enrolled, and their Demirjian stages were recorded. The associations between chronological age and Demirjian stages were evaluated. Dental formation was compared between sexes and jaws. Cutoff stages were determined to identify legal minor/major cases (above or below 18 years old). Age estimation formula was found for this population. Of the 150 included patients, 56 were males. The difference between the ages of males and females at each given developmental stage was nonsignificant (P > 0.05), except for the H stage. Age difference between same stage teeth of the maxilla and mandible was nonsignificant. Each of the G and H stages was significantly above 18 years old (P stages were below 18 years old (P stages and age were above 90% (all P development was positively affected by the chronological age (P = 0.000) and being maxillary (P = 0.000) but not sex (P = 0.113). Regression formula for age estimation was: age = 6.52+ (0.64 × sex) + (0.32 × arch) + (1.86 × Demirjian stage). Development of third molar might complete after the age 22. Iranian individuals with third molars at the G and H stages are likely above 18 while those at E and F are likely below 18. Pace of molar development differs for jaws, but intergender differences are open to further investigations.

  15. Correlation between Resistivity and Ground Penetrating Radar (GPR) Methods in Understanding the Signatures in Detecting Cavities

    Science.gov (United States)

    Afiq Saharudin, Muhamad; Maslinda, Umi; Hisham, Hazrul; Taqiuddin, Z. M.; Nur Amalina, M. K. A.; Nawawi, Nordiana Ahmad; Sulaiman, Nabila; Nordiana, M. M.; Azwin, I. N.

    2017-04-01

    The research was conducted using Resistivity and Ground Penetrating Radar (GPR) methods in detecting in-filled cavities and air-filled cavities. The importance of this study is to see the difference in conductivity value of the in-filled and air-filled cavity. The first study location in which the known target is air-cavity located at School of Language, Literacies, and Translation (SoLLAT). The next study location is at Desasiswa Bakti Permai, which the known target is a bunker with both were located at Universiti Sains Malaysia, Penang and the last location is at Gua Musang, Kelantan with suspected in-filled cavity. The result from Gua Musang is compared with both of the results that have been done at Universiti Sains Malaysia. The resistivity value of the first location that indicates the possible tunnel is about 500 Ωm to 800 Ωm and the conductivity value is about 0.0017 S/m. The resistivity value for the second location located at Desasiswa Bakti Permai that indicates the bunker is about 50 Ωm to 250 Ωm and the conductivity value is about 0.1104 S/m. The resistivity value from Gua Musang is about 50 Ωm to 100 Ωm and the conductivity value is about 0.0101 S/m. The velocity of the in-filled cavities is much lower compared with the velocity of the air-filled cavities. Based on the characteristics, Gua Musang area was dominated with in-filled cavities.

  16. Quasi-static tensile deformation and fracture behavior of a highly particle-filled composite using digital image correlation method

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Polymer bonded explosives (PBXs) are highly particle-filled composite materials.This paper experimentally studies the tensile deformation and fracture behavior of a PBX simulation by using the semi-circular bending (SCB) test.The deformation and fracture process of a pre-notched SCB sample with a random speckle pattern is recorded by a charge coupled device camera.The displacement and strain fields on the observed surface during the loading process are obtained by using the digital image correlation method....

  17. A Comparison Study of Canonical Correlation Analysis Based Methods for Detecting Steady-State Visual Evoked Potentials.

    Directory of Open Access Journals (Sweden)

    Masaki Nakanishi

    Full Text Available Canonical correlation analysis (CCA has been widely used in the detection of the steady-state visual evoked potentials (SSVEPs in brain-computer interfaces (BCIs. The standard CCA method, which uses sinusoidal signals as reference signals, was first proposed for SSVEP detection without calibration. However, the detection performance can be deteriorated by the interference from the spontaneous EEG activities. Recently, various extended methods have been developed to incorporate individual EEG calibration data in CCA to improve the detection performance. Although advantages of the extended CCA methods have been demonstrated in separate studies, a comprehensive comparison between these methods is still missing. This study performed a comparison of the existing CCA-based SSVEP detection methods using a 12-class SSVEP dataset recorded from 10 subjects in a simulated online BCI experiment. Classification accuracy and information transfer rate (ITR were used for performance evaluation. The results suggest that individual calibration data can significantly improve the detection performance. Furthermore, the results showed that the combination method based on the standard CCA and the individual template based CCA (IT-CCA achieved the highest performance.

  18. Variational method for estimating the effects of continuously varying lenses in HIFU, sonography, and sonography-based cross-correlation methods.

    Science.gov (United States)

    Alaniz, Alex; Kallel, Faouzi; Hungerford, Ed; Ophir, Jonathan

    2002-01-01

    The effects of high intensity focused ultrasound (HIFU)-induced continuously varying thermal gradients on sound ray propagation were modeled theoretically. This modeling was based on Fermat's variational principle of least time for rays propagating in a continuously varying thermal gradient described by a radially symmetric heat equation. Such thermal lenses dynamically affect HIFU beam focusing, and simultaneously create ultrasonic geometric and intensity distortions and artifacts in monitoring devices. Techniques which are based upon ultrasonic cross-correlation methods, such as elastography and two-dimensional temperature estimation, also suffer distortion effects and generate artifacts.

  19. Method of optical self-mixing for pulse wave transit time in comparison with other methods and correlation with blood pressure

    Science.gov (United States)

    Meigas, Kalju; Lass, Jaanus; Kattai, Rain; Karai, Deniss; Kaik, Juri

    2004-07-01

    This paper is a part of research to develop convenient method for continuous monitoring of arterial blood pressure by non-invasive and non-oscillometric way. A simple optical method, using self-mixing in a diode laser, is used for detection of skin surface vibrations near the artery. These vibrations, which can reveal the pulsate propagation of blood pressure waves along the vasculature, are used for pulse wave registration. The registration of the Pulse Wave Transit Time (PWTT) is based on computing the time delay in different regions of the human body using an ECG as a reference signal. In this study, the comparison of method of optical self-mixing with other methods as photoplethysmographic (PPG) and bioimpedance (BI) for PWTT is done. Also correlation of PWTT, obtained with different methods, with arterial blood pressure is calculated. In our study, we used a group of volunteers (34 persons) who made the bicycle exercise test. The test consisted of cycling sessions of increasing workloads during which the HR changed from 60 to 180 beats per minute. In addition, a blood pressure (NIBP) was registered with standard sphygmomanometer once per minute during the test and all NIBP measurement values were synchronized to other signals to find exact time moments where the systolic blood pressure was detected (Korotkoff sounds starting point). Computer later interpolated the blood pressure signal in order to get individual value for every heart cycle. The other signals were measured continuously during all tests. At the end of every session, a recovery period was included until person's NIBP and heart rate (HR) normalized. As a result of our study it turned out that time intervals that were calculated from plethysmographic (PPG) waveforms were in the best correlation with systolic blood pressure. The diastolic pressure does not correlate with any of the parameters representing PWTT. The pulse wave signals measured by laser and piezoelectric transducer are very similar

  20. Stress-energy tensor correlators in N-dimensional hot flat spaces via the generalized zeta-function method

    Science.gov (United States)

    Cho, H. T.; Hu, B. L.

    2012-09-01

    We calculate the expectation values of the stress-energy bitensor defined at two different spacetime points x, x‧ of a massless, minimally coupled scalar field with respect to a quantum state at finite temperature T in a flat N-dimensional spacetime by means of the generalized zeta-function method. These correlators, also known as the noise kernels, give the fluctuations of energy and momentum density of a quantum field which are essential for the investigation of the physical effects of negative energy density in certain spacetimes or quantum states. They also act as the sources of the Einstein-Langevin equations in stochastic gravity which one can solve for the dynamics of metric fluctuations as in spacetime foams. In terms of constitutions these correlators are one rung above (in the sense of the correlation—BBGKY or Schwinger-Dyson—hierarchies) the mean (vacuum and thermal expectation) values of the stress-energy tensor which drive the semiclassical Einstein equation in semiclassical gravity. The low- and the high-temperature expansions of these correlators are also given here: at low temperatures, the leading order temperature dependence goes like TN while at high temperatures they have a T2 dependence with the subleading terms exponentially suppressed by e-T. We also discuss the singular behavior of the correlators in the x‧ → x coincident limit as was done before for massless conformal quantum fields. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical in honour of Stuart Dowker’s 75th birthday devoted to ‘Applications of zeta functions and other spectral functions in mathematics and physics’.

  1. Deep reflection seismic imaging in SE Poland using extended correlation method applied to PolandSPAN™ data

    Science.gov (United States)

    Malinowski, M.

    2016-10-01

    Here I apply the extended correlation technique to a 156-km long regional seismic profile, PL1-5100, from the PolandSPAN™ survey located in SE Poland. This method allows the extension of the nominal record length of the survey (12 s in this case) to much longer times (22 s tested here), given that in the field the raw uncorrelated data were stored and a broadband sweep was used. Processing of the ground force correlated data compared to pilot sweep correlated one produced qualitatively similar results. Based on the consistency of the ground force measured along the profile, data were correlated with the mean of the ground force estimates. Results of the processing were validated against the coincident wide-angle reflection/refraction (WARR) profile (CELEBRATION 2000 CEL05 profile) and a deep reflection profile located further to the SE (POLCRUST-01 profile). I found a good correspondence between the wide-angle Moho signature and the near-vertical incidence (NVI) Moho reflectivity, both in terms of the depth and the reflection strength, with the exception of the area of the crustal keel (Moho > 50 km) interpreted from the WARR data, where the NVI reflectivity is observed at depth ca. 47 km. Similarly to POLCRUST-01, line PL1-5100 is portraying the attenuated crust of the East European Platform margin with the dipping crystalline basement down to ca. 20 km depth and the reflective lower crust. Two important fault zones: Izbica-Zamość Fault and Wilczopole Fault Zone are interpreted as the deeply-rooted crustal features, but there is no evidence for the Teisseyre-Tornquist Zone itself.

  2. Digital image correlation and finite element modelling as a method to determine mechanical properties of human soft tissue in vivo

    CERN Document Server

    Moerman, Kevin M; Evans, Sam L; Simms, Ciaran K

    2016-01-01

    The mechanical properties of human soft tissue are crucial for impact biomechanics, rehabilitation engineering and surgical simulation. Validation of these constitutive models using human data remains challenging and often requires the use of non-invasive imaging and inverse finite element (FE) analysis. Post processing data from imaging methods such as tagged magnetic resonance imaging (MRI) can be challenging. Digital Image Correlation (DIC) however is a relatively straightforward imaging method and thus the goal of this study was to assess the use of DIC in combination with FE modelling to determine the bulk material properties of human soft tissue. Indentation experiments were performed on a silicone gel soft tissue phantom. A two camera DIC setup was then used to record the 3D surface deformation. The experiment was then simulated using a FE model.

  3. HPLC method for the quantification of procyanidins in cocoa and chocolate samples and correlation to total antioxidant capacity.

    Science.gov (United States)

    Adamson, G E; Lazarus, S A; Mitchell, A E; Prior, R L; Cao, G; Jacobs, P H; Kremers, B G; Hammerstone, J F; Rucker, R B; Ritter, K A; Schmitz, H H

    1999-10-01

    Monomeric and oligomeric procyanidins present in cocoa liquors and chocolates were separated and quantified in four different laboratories using a normal-phase high-performance liquid chromatography (HPLC) method with fluorescence detection. Procyanidin standards through decamers were obtained by extraction from cocoa beans, enrichment by Sephadex LH-20 gel permeation chromatography, and final purification by preparative normal-phase HPLC. The purity of each oligomeric fraction was assessed using HPLC coupled to mass spectrometry. A composite standard was then prepared, and calibration curves were generated for each oligomeric class using a quadratic fit of area sum versus concentration. Results obtained by each of the laboratories were in close agreement, which suggests this method is reliable and reproducible for quantification of procyanidins. Furthermore, the procyanidin content of the samples was correlated to the antioxidant capacity measured using the ORAC assay as an indicator for potential biological activity.

  4. Localization of Peripheral Pulmonary Lesions Using a Method of Computed Tomography-Anatomic Correlation and Radial Probe Endobronchial Ultrasound Confirmation.

    Science.gov (United States)

    Chen, Alexander C; Loiselle, Andrea; Zhou, Li; Baty, Jack; Misselhorn, David

    2016-09-01

    Peripheral pulmonary lesions requiring a diagnosis continue to present challenges to clinicians. One significant barrier is the inability to reliably locate peripheral lesions by bronchoscopic approaches. Multiplanar computed tomographic (CT) scan reconstruction is available to most physicians and provides axial, coronal, and sagittal images that may be used to estimate target lesion location and guide bronchoscopists during procedures. This study was performed to evaluate a systematic method of CT-anatomic correlation based on multiplanar reconstruction CT scanning with monoplanar fluoroscopy during bronchoscopy to locate peripheral pulmonary lesions and confirm lesion location, using radial probe endobronchial ultrasound. A retrospective review of peripheral bronchoscopy cases in which radial probe endobronchial ultrasound for peripheral lesions was performed at a tertiary care, university hospital. All cases involved a systematic approach of reviewing axial, coronal, and sagittal CT reconstructions, coupled with monoplanar fluoroscopy during procedures to assist with locating peripheral lesions. Using the method of CT-anatomic correlation, 332 of 348 (95.4%) of all lesions were successfully localized and confirmed, using radial probe endobronchial ultrasound. Lesions 1-2 cm in size accounted for 45% of all lesions, and the ability to locate lesions was not significantly different based on lesion size. Mean time to lesion localization was 6.8 minutes. Larger lesions and lesions demonstrating an air bronchus sign on CT scan were located in less time. The overall diagnostic yield was 58.9%. A systematic approach applying CT-anatomic correlation with multiplanar CT scan reconstruction and monoplanar fluoroscopy during procedures can result in an efficient, and successful process for locating peripheral pulmonary lesions.

  5. A New Method for Recognition of Arcing Faults in Transmission Lines using Wavelet Transform and Correlation Coefficient

    Directory of Open Access Journals (Sweden)

    Navid Ghaffarzadeh

    2013-03-01

    Full Text Available In this paper a novel method based on discrete wavelet transform and correlation coefficient is presented for distinguishing between arcing and permanent faults. The algorithm includes offline and online processing. In the offline, discrete wavelet transform is used to decompose typical faulted phase voltage waveforms during arcing faults. An index is then defined and computed. The index is based on the normalised energy of detail coefficients at resolution levels 1 to 14. The online processing consists of capturing the faulted phase voltage waveform using a 20 kHz sampling rate, and decomposing it by db4. Finally, arcing faults are distinguished from permanent faults based on correlation coefficient of the computed index of the pre-stored typical arcing faults and a recorded indistinct signal. The effectiveness of the approach has been tested for numerous arcing and permanent fault conditions on a transmission line using the Electromagnetic transient Program (EMTP software tool. The simulation results show the capability of the proposed method in distinguishing between arcing faults from permanent faults.

  6. Laboratory Earthquake Measurements with the High-speed Digital Image Correlation Method and Applications to Super-shear Transition

    Science.gov (United States)

    Rubino, V.; Lapusta, N.; Rosakis, A.

    2012-12-01

    Mapping full-field displacements and strains on the Earth's surface during an earthquake is of paramount importance to enhance our understanding of earthquake mechanics. In this study, the feasibility of such measurements using image correlation methods is investigated in a laboratory earthquake setup. Earthquakes are mimicked in the laboratory by dynamic rupture propagating along an inclined frictional interface formed by two Homalite plates under compression, using the configuration developed by Rosakis and coworkers (e.g., Rosakis et al., 2007). In our study, the interface is partially glued, in order to confine the rupture before it reaches the ends of the specimen. The specimens are painted with a speckle pattern to provide the surface with characteristic features for image matching. Images of the specimens are taken before and after dynamic rupture with a 4 Megapixels resolution CCD camera. The digital images are analyzed with two software packages: VIC-2D (Correlated Solutions Inc.) and COSI-Corr (Leprince et. al, 2007). Both VIC-2D and COSI-Corr are able to characterize the full-field static displacement of a dynamic crack. For example, in a case with secondary mode I cracks, the correlation analysis performed with either software clearly shows (i) the relative displacement (slip) along the frictional interface, (ii) the rupture arrest on the glued boundaries, and (iii) the presence of two wing cracks. The obtained displacement measurements are converted to strains, using de-noising techniques. The digital image correlation method is then used in combination with high-speed photography. We will report our progress on the study of a spontaneously expanding sub-Rayleigh shear crack advancing along an interface containing a patch of favorable heterogeneity, such as a preexisting subcritical crack or a patch with higher prestress. According to the predictions of Liu and Lapusta (2008), intersonic transition and propagation can be achieved in the presence of a

  7. Treatment of overlapping gaseous absorption with the correlated-k method in hot Jupiter and brown dwarf atmosphere models

    CERN Document Server

    Amundsen, David S; Manners, James; Baraffe, Isabelle; Mayne, Nathan J

    2016-01-01

    The correlated-k method is frequently used to speed up radiation calculations in both one-dimensional and three-dimensional atmosphere models. An inherent difficulty with this method is how to treat overlapping absorption, i.e. absorption by more than one gas in a given spectral region. We have evaluated the applicability of three different methods in hot Jupiter and brown dwarf atmosphere models, all of which have been previously applied within models in the literature: (i) Random overlap, both with and without resorting and rebinning, (ii) equivalent extinction and (iii) pre-mixing of opacities, where (i) and (ii) combine k-coefficients for different gases to obtain k-coefficients for a mixture of gases, while (iii) calculates k-coefficients for a given mixture from the corresponding mixed line-by-line opacities. We find that the random overlap method is the most accurate and flexible of these treatments, and is fast enough to be used in one-dimensional models with resorting and rebinning. In three-dimensio...

  8. Experimental validation for the determination of particle positions by the correlation coefficient method in digital particle holography.

    Science.gov (United States)

    Yang, Yan; Kang, Bo-seon

    2008-11-10

    The feasibility and the accuracy of the correlation coefficient (CC) method for the determination of particle positions along the optical axis in digital particle holography were verified by validation experiments. A translation system capable of high precision was used to move the particle objects by exact known distances between several different positions. The particle positions along the optical axis were calculated by the CC method and compared with their exact values to obtain the errors of the focus plane determination. The tested particles were two-dimensional (2D) dots in a calibration target along with different-sized glass beads and droplets that reflected and caused a three-dimensional (3D) effect. The results show that the CC method can work well for both the 2D dots and the 3D particles. The effect of other particles on the focus plane determination was also investigated. The CC method can locate the focus plane of particles with high precision, regardless of the existence of other particles.

  9. Comparison of methods for estimating the intraclass correlation coefficient for binary responses in cancer prevention cluster randomized trials.

    Science.gov (United States)

    Wu, Sheng; Crespi, Catherine M; Wong, Weng Kee

    2012-09-01

    The intraclass correlation coefficient (ICC) is a fundamental parameter of interest in cluster randomized trials as it can greatly affect statistical power. We compare common methods of estimating the ICC in cluster randomized trials with binary outcomes, with a specific focus on their application to community-based cancer prevention trials with primary outcome of self-reported cancer screening. Using three real data sets from cancer screening intervention trials with different numbers and types of clusters and cluster sizes, we obtained point estimates and 95% confidence intervals for the ICC using five methods: the analysis of variance estimator, the Fleiss-Cuzick estimator, the Pearson estimator, an estimator based on generalized estimating equations and an estimator from a random intercept logistic regression model. We compared estimates of the ICC for the overall sample and by study condition. Our results show that ICC estimates from different methods can be quite different, although confidence intervals generally overlap. The ICC varied substantially by study condition in two studies, suggesting that the common practice of assuming a common ICC across all clusters in the trial is questionable. A simulation study confirmed pitfalls of erroneously assuming a common ICC. Investigators should consider using sample size and analysis methods that allow the ICC to vary by study condition.

  10. Communication: Proton NMR dipolar-correlation effect as a method for investigating segmental diffusion in polymer melts

    Science.gov (United States)

    Lozovoi, A.; Mattea, C.; Herrmann, A.; Rössler, E. A.; Stapf, S.; Fatkullin, N.

    2016-06-01

    A simple and fast method for the investigation of segmental diffusion in high molar mass polymer melts is presented. The method is based on a special function, called proton dipolar-correlation build-up function, which is constructed from Hahn Echo signals measured at times t and t/2. The initial rise of this function contains additive contributions from both inter- and intramolecular magnetic dipole-dipole interactions. The intermolecular contribution depends on the relative mean squared displacements (MSDs) of polymer segments from different macromolecules, while the intramolecular part reflects segmental reorientations. Separation of both contributions via isotope dilution provides access to segmental displacements in polymer melts at millisecond range, which is hardly accessible by other methods. The feasibility of the method is illustrated by investigating protonated and deuterated polybutadiene melts with molecular mass 196 000 g/mol at different temperatures. The observed exponent of the power law of the segmental MSD is close to 0.32 ± 0.03 at times when the root MSD is in between 45 Å and 75 Å, and the intermolecular proton dipole-dipole contribution to the total proton Hahn Echo NMR signal is larger than 50% and increases with time.

  11. Influence of electron correlation and degeneracy on the Fukui matrix and extension of frontier molecular orbital theory to correlated quantum chemical methods.

    Science.gov (United States)

    Bultinck, Patrick; Van Neck, Dimitri; Acke, Guillaume; Ayers, Paul W

    2012-02-21

    The Fukui function is considered as the diagonal element of the Fukui matrix in position space, where the Fukui matrix is the derivative of the one particle density matrix (1DM) with respect to the number of electrons. Diagonalization of the Fukui matrix, expressed in an orthogonal orbital basis, explains why regions in space with negative Fukui functions exist. Using a test set of molecules, electron correlation is found to have a remarkable effect on the eigenvalues of the Fukui matrix. The Fukui matrices at the independent electron model level are mathematically proven to always have an eigenvalue equal to exactly unity while the rest of the eigenvalues possibly differ from zero but sum to zero. The loss of idempotency of the 1DM at correlated levels of theory causes the loss of these properties. The influence of electron correlation is examined in detail and the frontier molecular orbital concept is extended to correlated levels of theory by defining it as the eigenvector of the Fukui matrix with the largest eigenvalue. The effect of degeneracy on the Fukui matrix is examined in detail, revealing that this is another way by which the unity eigenvalue and perfect pairing of eigenvalues can disappear.

  12. Treatment of overlapping gaseous absorption with the correlated-k method in hot Jupiter and brown dwarf atmosphere models

    Science.gov (United States)

    Amundsen, David S.; Tremblin, Pascal; Manners, James; Baraffe, Isabelle; Mayne, Nathan J.

    2017-02-01

    The correlated-k method is frequently used to speed up radiation calculations in both one-dimensional and three-dimensional atmosphere models. An inherent difficulty with this method is how to treat overlapping absorption, i.e. absorption by more than one gas in a given spectral region. We have evaluated the applicability of three different methods in hot Jupiter and brown dwarf atmosphere models, all of which have been previously applied within models in the literature: (i) random overlap, both with and without resorting and rebinning, (ii) equivalent extinction and (iii) pre-mixing of opacities, where (i) and (ii) combine k-coefficients for different gases to obtain k-coefficients for a mixture of gases, while (iii) calculates k-coefficients for a given mixture from the corresponding mixed line-by-line opacities. We find that the random overlap method is the most accurate and flexible of these treatments, and is fast enough to be used in one-dimensional models with resorting and rebinning. In three-dimensional models such as global circulation models (GCMs) it is too slow, however, and equivalent extinction can provide a speed-up of at least a factor of three with only a minor loss of accuracy while at the same time retaining the flexibility gained by combining k-coefficients computed for each gas individually. Pre-mixed opacities are significantly less flexible, and we also find that particular care must be taken when using this method in order to to adequately resolve steep variations in composition at important chemical equilibrium boundaries. We use the random overlap method with resorting and rebinning in our one-dimensional atmosphere model and equivalent extinction in our GCM, which allows us to e.g. consistently treat the feedback of non-equilibrium chemistry on the total opacity and therefore the calculated P-T profiles in our models.

  13. Comparing Geophysical Methods for Determining the Thickness of Arctic Sea Ice: Is There a Correlation Between Thickness and Surface Temperature?

    Science.gov (United States)

    Robertson, R.; Bowman, T.; Eagle, J. L.; Fisher, L.; Mankowski, K.; McGrady, N.; Schrecongost, N.; Voll, H.; Zulfiqar, A.; Herman, R. B.

    2016-12-01

    Several small geophysical surveys were conducted on the Chukchi Sea ice just offshore from the Naval Arctic Research Laboratory near Barrow, Alaska, in March, 2016. The goal was to investigate a possible correlation between the surface temperature and the thickness of the sea ice, as well as to test a potential new method for more accurately determining ice thickness. Surveys were conducted using a capacitively coupled resistivity array, a custom built thermal sensor array sled, ground penetrating radar (GPR), and an ice drill. The thermal sensor array was based on an Arduino microcontroller. It used an infrared (IR) sensor to determine surface temperature, and thermistor-based sensors to determine vertical air temperatures at 6 evenly spaced heights up to a maximum of 1.5 meters. Surface temperature (IR) data show possible correlations with ice drill, resistivity, and GPR data. The vertical air sensors showed almost no variation for any survey line which we postulate is due to the constant wind during each survey. Ice drill data show ice thickness along one 200 meter line varied from 79-95 cm, with an average of 87 cm. The thickness appears to be inversely correlated to surface temperatures. Resistivity and IR data both showed abrupt changes when crossing from the shore to the sea ice along a 400 meter line. GPR and IR data showed similar changes along a separate 900 meter line, suggesting that surface temperature and subsurface composition are related. Resistivity data were obtained in two locations by using the array in an expanding dipole-dipole configuration with 2.5 meter dipoles. The depth to the ice/water boundary was calculated using a "cumulative resistivity" plot and matched the depths obtained via the ice drill to within 2%. This has initiated work to develop a microcontroller-based resistivity array specialized for thickness measurements of thin ice.

  14. Development and Application of Explicitly Correlated Wave Function Based Methods for the Investigation of Optical Properties of Semiconductor Nanomaterials

    Science.gov (United States)

    Elward, Jennifer Mary

    Semiconductor nanoparticles, or quantum dots (QDs), are well known to have very unique optical and electronic properties. These properties can be controlled and tailored as a function of several influential factors, including but not limited to the particle size and shape, effect of composition and heterojunction as well as the effect of ligand on the particle surface. This customizable nature leads to extensive experimental and theoretical research on the capabilities of these quantum dots for many application purposes. However, in order to be able to understand and thus further the development of these materials, one must first understand the fundamental interaction within these nanoparticles. In this thesis, I have developed a theoretical method which is called electron-hole explicitly correlated Hartee-Fock (eh-XCHF). It is a variational method for solving the electron-hole Schrodinger equation and has been used in this work to study electron-hole interaction in semiconductor quantum dots. The method was benchmarked with respect to a parabolic quantum dot system, and ground state energy and electron-hole recombination probability were computed. Both of these properties were found to be in good agreement with expected results. Upon successful benchmarking, I have applied the eh-XCHF method to study optical properties of several quantum dot systems including the effect of dot size on exciton binding energy and recombination probability in a CdSe quantum dot, the effect of shape on a CdSe quantum dot, the effect of heterojunction on a CdSe/ZnS quantum dot and the effect of quantum dot-biomolecule interaction within a CdSe-firefly Luciferase protein conjugate system. As metrics for assessing the effect of these influencers on the electron-hole interaction, the exciton binding energy, electron-hole recombination probability and the average electron-hole separation distance have been computed. These excitonic properties have been found to be strongly infuenced by the

  15. An adaptive line enhancement method for UWB proximity fuze signal processing based on correlation matrix estimation with time delay factor

    Science.gov (United States)

    Li, Meng; Huang, Zhonghua

    2016-10-01

    Signal processing for an ultra-wideband radio fuze receiver involves some challenges: it requires high real-time performance; the output signal is mixed with broadband noise; and the signal-to-noise ratio (SNR) decreases with increased detection range. The adaptive line enhancement method is used to filter the output signal of the ultra-wideband radio fuze receiver, and thus suppress the wideband noise from the output signal of the receiver and extract the target characteristic signal. The filter input correlation matrix estimation algorithm is based on the delay factor of an adaptive line enhancer. The proposed adaptive algorithm was used to filter and reduce noise in the output signal from the fuze receiver. Simulation results showed that the SNR of the output signal after adaptive noise reduction was improved by 20 dB, which was higher than the SNR of the output signal after finite impulse response (FIR) filtering of around 10 dB.

  16. Real-Time and Robust Method for Hand Gesture Recognition System Based on Cross-Correlation Coefficient

    Directory of Open Access Journals (Sweden)

    Reza Azad

    2013-11-01

    Full Text Available Hand gesture recognition possesses extensive applications in virtual reality, sign language recognition, and computer games. The direct interface of hand gestures provides us a new way for communicating with the virtual environment. In this paper a novel and real-time approach for hand gesture recognition system is presented. In the suggested method, first, the hand gesture is extracted from the main image by the image segmentation and morphological operation and then is sent to feature extraction stage. In feature extraction stage the Cross-correlation coefficient is applied on the gesture to recognize it. In the result part, the proposed approach is applied on American Sign Language (ASL database and the accuracy rate obtained 98.34%.

  17. Stochastic growth theory of molecular beam epitaxy with atom correlation effects: A Monte-Carlo master equation method

    Science.gov (United States)

    Nakayama, Hiroshi; Furuichi, Akihisa; Kita, Takashi; Nishino, Taneo

    1997-04-01

    Structural phase transition of epitaxial growing layer is quite important to understand the atomic scale mechanism of molecular beam epitaxy (MBE). GaAs and related alloy semiconductors are typical systems which show variety of such structural transitions during MBE. Structural evolution of surface reconstruction phases and an order-disorder transition in III-V alloy semiconductors are typical cases where such phase transitions appear during epitaxial processes. In this work, a stochastic theory and the Monte-Carlo simulation have been presented to describe the structural evolution of epitaxial growth in binary system. This method, known here as the 'Monte-Carlo master equation (MCME) method', couples a master equation for epitaxial growth kinetics with an Ising Hamiltonian of growing surface. The Monte-Carlo (MC) simulation of binary growing surface with atom-correlation effects has successfully revealed the evolution of atomic structure and the formation of short-range ordering (SRO) during epitaxy. This demonstrates the usefulness of the MCME method in describing the atomic-structural dynamics as compared with a conventional theory of epitaxy based on a diffusion equation and standard nucleation theory.

  18. Detection and Identification of Multiple Stationary Human Targets Via Bio-Radar Based on the Cross-Correlation Method

    Directory of Open Access Journals (Sweden)

    Yang Zhang

    2016-10-01

    Full Text Available Ultra-wideband (UWB radar has been widely used for detecting human physiological signals (respiration, movement, etc. in the fields of rescue, security, and medicine owing to its high penetrability and range resolution. In these applications, especially in rescue after disaster (earthquake, collapse, mine accident, etc., the presence, number, and location of the trapped victims to be detected and rescued are the key issues of concern. Ample research has been done on the first issue, whereas the identification and localization of multi-targets remains a challenge. False positive and negative identification results are two common problems associated with the detection of multiple stationary human targets. This is mainly because the energy of the signal reflected from the target close to the receiving antenna is considerably stronger than those of the targets at further range, often leading to missing or false recognition if the identification method is based on the energy of the respiratory signal. Therefore, a novel method based on cross-correlation is proposed in this paper that is based on the relativity and periodicity of the signals, rather than on the energy. The validity of this method is confirmed through experiments using different scenarios; the results indicate a discernible improvement in the detection precision and identification of the multiple stationary targets.

  19. Scalable Electron Correlation Methods. 2. Parallel PNO-LMP2-F12 with Near Linear Scaling in the Molecular Size.

    Science.gov (United States)

    Ma, Qianli; Werner, Hans-Joachim

    2015-11-10

    We present an efficient explicitly correlated pair natural orbital local second-order Møller-Plesset perturbation theory (PNO-LMP2-F12) method. The method is an extension of our previously reported PNO-LMP2 approach [ Werner et al. J. Chem. Theory Comput. 2015 , 11 , 484 ]. Near linear scaling with the size of molecule is achieved by using domain approximations on both virtual and occupied orbitals, local density fitting (DF), and local resolution of the identity (RI), and by exploiting the sparsity of the local molecular orbitals (LMOs) as well as of projected atomic orbitals (PAOs). All large data structures used in the method are stored in distributed memory using Global Arrays (GAs) to achieve near inverse-linear scaling with the number of processing cores, provided that the GAs can be efficiently and independently accessed from all cores. The effect of the various domain approximations is tested for a wide range of chemical reactions. The PNO-LMP2-F12 reaction energies deviate from the canonical DF-MP2-F12 results by ≤1 kJ mol(-1) using triple-ζ (VTZ-F12) basis sets and are close to the complete basis set limits. PNO-LMP2-F12 calculations on molecules of chemical interest involving a few thousand basis functions can be performed within an hour or less using a few nodes on a small computer cluster.

  20. A model-based method for computation of correlation dimension, Lyapunov exponents and synchronization from depth-EEG signals.

    Science.gov (United States)

    Shayegh, F; Sadri, S; Amirfattahi, R; Ansari-Asl, K

    2014-01-01

    In order to predict epileptic seizures many precursory features, extracted from the EEG signals, have been introduced. Before checking out the performance of features in detection of pre-seizure state, it is required to see whether these features are accurately extracted. Evaluation of feature estimation methods has been less considered, mainly due to the lack of a ground truth for the real EEG signals' features. In this paper, some simulated long-term depth-EEG signals, with known state spaces, are generated via a realistic neural mass model with physiological parameters. Thanks to the known ground truth of these synthetic signals, they are suitable for evaluating different algorithms used to extract the features. It is shown that conventional methods of estimating correlation dimension, the largest Lyapunov exponent, and phase coherence have non-negligible errors. Then, a parameter identification-based method is introduced for estimating the features, which leads to better estimation results for synthetic signals. It is shown that the neural mass model is able to reproduce real depth-EEG signals accurately; thus, assuming this model underlying real depth-EEG signals, can improve the accuracy of features' estimation.

  1. Effect of Sr-modification on the bendability of cast aluminum alloy A356 using digital image correlation method

    Energy Technology Data Exchange (ETDEWEB)

    Marzouk, M.; Jain, M., E-mail: jainmk@mcmaster.ca; Shankar, S.

    2014-03-01

    The effect of cast microstructure on bendability of automotive cast aluminum alloy A356 has been studied by machining sheet specimens and conducting V-bend tests. Specimens in the loaded condition are observed from the through-thickness section using a CCD camera and also using a scanning electron microscope (SEM). The latter allowed recording of high magnification images from the through-thickness region of the bend to determine aspects of strain localization and particle induced damage in the microstructure. In addition, the initial microstructure is utilized as a speckle pattern for further analysis of through-thickness strain development in the bent region using digital image correlation (DIC) method. The method is applied to unmodified and Sr-modified A356 compositions. The results indicate superior bendability of Sr modified A356 alloy compared to the unmodified alloy. The differences in bendability are attributed to the size and morphology of eutectic Si phase particles that undergo significant cracking in the tensile region of specimen during bending. The results demonstrate that high magnification SEM imaging of bent specimens coupled with DIC based strain analysis offers a useful method of analyzing the effect of microstructure on bendability of cast materials.

  2. Development and validation of a stability-indicating capillary zone electrophoretic method for the assessment of entecavir and its correlation with liquid chromatographic methods.

    Science.gov (United States)

    Dalmora, Sergio Luiz; Nogueira, Daniele Rubert; D'Avila, Felipe Bianchini; Souto, Ricardo Bizogne; Leal, Diogo Paim

    2011-01-01

    A stability-indicating capillary zone electrophoresis (CZE) method was validated for the analysis of entecavir in pharmaceutical formulations, using nimesulide as an internal standard. A fused-silica capillary (50 µm i.d.; effective length, 40 cm) was used while being maintained at 25°C; the applied voltage was 25 kV. A background electrolyte solution consisted of a 20 mM sodium tetraborate solution at pH 10. Injections were performed using a pressure mode at 50 mbar for 5 s, with detection at 216 nm. The specificity and stability-indicating capability were proven through forced degradation studies, evaluating also the in vitro cytotoxicity test of the degraded products. The method was linear over the concentration range of 1-200 µg mL(-1) (r(2) = 0.9999), and was applied for the analysis of entecavir in tablet dosage forms. The results were correlated to those of validated conventional and fast LC methods, showing non-significant differences (p > 0.05).

  3. Computing Wigner distributions and time correlation functions using the quantum thermal bath method: application to proton transfer spectroscopy.

    Science.gov (United States)

    Basire, Marie; Borgis, Daniel; Vuilleumier, Rodolphe

    2013-08-14

    Langevin dynamics coupled to a quantum thermal bath (QTB) allows for the inclusion of vibrational quantum effects in molecular dynamics simulations at virtually no additional computer cost. We investigate here the ability of the QTB method to reproduce the quantum Wigner distribution of a variety of model potentials, designed to assess the performances and limits of the method. We further compute the infrared spectrum of a multidimensional model of proton transfer in the gas phase and in solution, using classical trajectories sampled initially from the Wigner distribution. It is shown that for this type of system involving large anharmonicities and strong nonlinear coupling to the environment, the quantum thermal bath is able to sample the Wigner distribution satisfactorily and to account for both zero point energy and tunneling effects. It leads to quantum time correlation functions having the correct short-time behavior, and the correct associated spectral frequencies, but that are slightly too overdamped. This is attributed to the classical propagation approximation rather than the generation of the quantized initial conditions themselves.

  4. Morphological correlates of sprint swimming speed in five species of spadefoot toad tadpoles: comparison of morphometric methods.

    Science.gov (United States)

    Arendt, Jeff

    2010-09-01

    The relationship between vertebrate morphology and swimming performance has long interested biologists. Recent work on predator-induced morphological plasticity of anuran tadpoles has increased this interest. Here, I use data on five species of spadefoot toad tadpoles (Scaphiopodidae) to compare linear and geometric morphometrics. Linear measures explain only 7-26% of the variation in swimming speed, depending on species, whereas geometric morphometrics could explain 24-46% of the same variation. I also compare two methods for examining how similar the morphology-swimming speed relationship is among species. A canonical variate derived from a MANCOVA approach successfully detected species differences in these relationships, whether using linear or geometric methods, but a canonical correlation approach failed in both cases. Overall, tadpoles with smaller bodies, larger tails, and larger tail muscles are faster swimmers but the details of how these shape changes are achieved differed among species. For example, in some species a smaller body was achieved primarily by reducing abdomen size, whereas in others both the head and abdomen are smaller.Faster swimmers also had deeper tails, especially in the posterior half of the tail. This pattern would have been missed in standard linear morphometrics which usually only measures maximum tail depth.

  5. Catalytic activity vs. size correlation in platinum catalysts of PEM fuel cells prepared on carbon black by different methods

    Energy Technology Data Exchange (ETDEWEB)

    Nores-Pondal, F.J.; Granada, M.; Corti, H.R. [Departamento de Fisica de la Materia Condensada, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica (CNEA), General Paz 1499, 1650 San Martin, Buenos Aires (Argentina); Vilella, I.M.J.; de Miguel, S.R.; Scelza, O.A. [Instituto de Investigaciones en Catalisis y Petroquimica (INCAPE), Facultad de Ingenieria Quimica (Universidad Nacional del Litoral) - CONICET, Santiago del Estero 2654, 3000 Santa Fe (Argentina); Troiani, H. [Departamento de Fisica, Centro Atomico Bariloche, Comision Nacional de Energia Atomica (CNEA), Av. Bustillo 9500, 8400 San Carlos de Bariloche (Argentina)

    2009-10-15

    In this work nanoparticulated platinum catalysts have been prepared on carbon Vulcan XC-72 using three methods starting with chloroplatinic acid as a precursor: (i) formic acid as a reductor agent; (ii) impregnation method followed by reduction in hydrogen atmosphere at moderated temperature; and (iii) microwave-assisted reduction in ethylene glycol. The catalytic and size studies were also performed on a commercial Pt catalyst (E-Tek, De Nora). The characterization of the particle size and distribution was performed by means of transmission electron microscopy (TEM) and X-ray diffraction (XRD). The characterizations of the catalytic and electrocatalytic properties of the catalysts were determined by studying the cyclohexane dehydrogenation reaction (CHD) and the behavior under cyclic voltammetry (CV) in sulfuric acid solutions. The measured electrochemical activity, along with the hydrogen chemisorption of the catalysts allows the estimation of effective particle sizes, which are much larger than those measured by TEM and XRD. The catalysts prepared by reduction with formic acid and ethylene glycol (microwave-assisted) show electrochemical activities very close to those of the commercial catalyst, and are almost insensitive to the Pt dispersion or Pt particle size. The chemical activity in CHD correlates well with the metallic dispersion determined by hydrogen chemisorption, indicating similar accesibility of H{sub 2} and cyclohexane to the catalyst surface. (author)

  6. Correlation Between An In-vitro Method And An In-vivo Method In Assessing Bioavailable Arsenic In Two Pesticide-Amended Soils

    Science.gov (United States)

    Quazi, S.; Sarkar, D.; Sylvia, V.; Datta, R.

    2006-05-01

    Health risk assessment of Arsenic (As) enriched soil requires the estimation of bioavailable fraction of total metal. Research has been conducted to gain a better understanding of the relationship between metal availability and risk assessment. Some baseline risk assessments developed for contaminated sites have used the conservative assumption that all (i.e. 100%) of the As present in soils and wastes is bioavailable, due to tremendous cost associated with in-vivo bioavailability studies. This potentially overestimates the actual health risk, elevating the expenses associated with site cleanup. Health risk from direct exposure to soil-As via the hand-to-mouth exposure route is restricted only to those fractions of As in the soil that are available to the human gastrointestinal system. A reasonable approach is to develop in-vitro methods that simulate the complex and dynamic human gastrointestinal system and correlate well with the results of in-vivo method. Thus this study aims in addressing the potential of one such in-vitro method developed by our research group in assessing the bioavailability of soil-As. Two soils with drastically different chemical characteristics in regards to As reactivity (Immokalee-low As retention capacity; Millhopper-high As retention capacity) spiked with a pesticide (sodium arsenate) were used. Soils were amended at two rates representing concentrations typically found at Superfund sites: 675 and 1500 mg/kg of As. In-vitro bioavailability experiments were performed in order to obtain an estimate of the amount of As likely to be available in the human gastrointestinal system as well as the fraction potentially absorbed onto the intestinal linings. Following the in-vitro study selective in-vivo bioavailability studies using As-contaminated soils were conducted on male and female mice to validate the in-vitro results via comparison with the in-vivo data. Soils were administered orally to the BALB/c mice immediately after spiking

  7. Density functional theory embedding for correlated wavefunctions: improved methods for open-shell systems and transition metal complexes.

    Science.gov (United States)

    Goodpaster, Jason D; Barnes, Taylor A; Manby, Frederick R; Miller, Thomas F

    2012-12-14

    Density functional theory (DFT) embedding provides a formally exact framework for interfacing correlated wave-function theory (WFT) methods with lower-level descriptions of electronic structure. Here, we report techniques to improve the accuracy and stability of WFT-in-DFT embedding calculations. In particular, we develop spin-dependent embedding potentials in both restricted and unrestricted orbital formulations to enable WFT-in-DFT embedding for open-shell systems, and develop an orbital-occupation-freezing technique to improve the convergence of optimized effective potential calculations that arise in the evaluation of the embedding potential. The new techniques are demonstrated in applications to the van-der-Waals-bound ethylene-propylene dimer and to the hexa-aquairon(II) transition-metal cation. Calculation of the dissociation curve for the ethylene-propylene dimer reveals that WFT-in-DFT embedding reproduces full CCSD(T) energies to within 0.1 kcal/mol at all distances, eliminating errors in the dispersion interactions due to conventional exchange-correlation (XC) functionals while simultaneously avoiding errors due to subsystem partitioning across covalent bonds. Application of WFT-in-DFT embedding to the calculation of the low-spin/high-spin splitting energy in the hexaaquairon(II) cation reveals that the majority of the dependence on the DFT XC functional can be eliminated by treating only the single transition-metal atom at the WFT level; furthermore, these calculations demonstrate the substantial effects of open-shell contributions to the embedding potential, and they suggest that restricted open-shell WFT-in-DFT embedding provides better accuracy than unrestricted open-shell WFT-in-DFT embedding due to the removal of spin contamination.

  8. Impact of CT attenuation correction method on quantitative respiratory-correlated (4D) PET/CT imaging

    Energy Technology Data Exchange (ETDEWEB)

    Nyflot, Matthew J., E-mail: nyflot@uw.edu [Department of Radiation Oncology, University of Washington, Seattle, Washington 98195-6043 (United States); Lee, Tzu-Cheng [Department of Bioengineering, University of Washington, Seattle, Washington 98195-6043 (United States); Alessio, Adam M.; Kinahan, Paul E. [Department of Radiology, University of Washington, Seattle, Washington 98195-6043 (United States); Wollenweber, Scott D.; Stearns, Charles W. [GE Healthcare, Waukesha, Wisconsin 53188 (United States); Bowen, Stephen R. [Department of Radiation Oncology, University of Washington, Seattle, Washington 98195-6043 and Department of Radiology, University of Washington, Seattle, Washington 98195-6043 (United States)

    2015-01-15

    Purpose: Respiratory-correlated positron emission tomography (PET/CT) 4D PET/CT is used to mitigate errors from respiratory motion; however, the optimal CT attenuation correction (CTAC) method for 4D PET/CT is unknown. The authors performed a phantom study to evaluate the quantitative performance of CTAC methods for 4D PET/CT in the ground truth setting. Methods: A programmable respiratory motion phantom with a custom movable insert designed to emulate a lung lesion and lung tissue was used for this study. The insert was driven by one of five waveforms: two sinusoidal waveforms or three patient-specific respiratory waveforms. 3DPET and 4DPET images of the phantom under motion were acquired and reconstructed with six CTAC methods: helical breath-hold (3DHEL), helical free-breathing (3DMOT), 4D phase-averaged (4DAVG), 4D maximum intensity projection (4DMIP), 4D phase-matched (4DMATCH), and 4D end-exhale (4DEXH) CTAC. Recovery of SUV{sub max}, SUV{sub mean}, SUV{sub peak}, and segmented tumor volume was evaluated as RC{sub max}, RC{sub mean}, RC{sub peak}, and RC{sub vol}, representing percent difference relative to the static ground truth case. Paired Wilcoxon tests and Kruskal–Wallis ANOVA were used to test for significant differences. Results: For 4DPET imaging, the maximum intensity projection CTAC produced significantly more accurate recovery coefficients than all other CTAC methods (p < 0.0001 over all metrics). Over all motion waveforms, ratios of 4DMIP CTAC recovery were 0.2 ± 5.4, −1.8 ± 6.5, −3.2 ± 5.0, and 3.0 ± 5.9 for RC{sub max}, RC{sub peak}, RC{sub mean}, and RC{sub vol}. In comparison, recovery coefficients for phase-matched CTAC were −8.4 ± 5.3, −10.5 ± 6.2, −7.6 ± 5.0, and −13.0 ± 7.7 for RC{sub max}, RC{sub peak}, RC{sub mean}, and RC{sub vol}. When testing differences between phases over all CTAC methods and waveforms, end-exhale phases were significantly more accurate (p = 0.005). However, these differences were driven by

  9. Measuring DHEA-S in saliva: time of day differences and positive correlations between two different types of collection methods

    Directory of Open Access Journals (Sweden)

    Klein Laura C

    2010-07-01

    Full Text Available Abstract Background The anabolic steroid, dehydroepiandosterone sulfate (DHEA-S, is secreted from the adrenal cortex. It plays a significant role in the body as a precursor to sex steroids as well as a lesser known role in the hypothalamic pituitary adrenal axis (HPA response to stress. DHEA-S can be measured reliably in saliva, making saliva collection a valuable tool for health research because it minimizes the need for invasive sampling procedures (e.g., blood draws. Typical saliva collection methods include the use of plain cotton swab collection devices (e.g., Salivette® or passive drool. There has been some speculation that the plain saliva cotton collection device may interfere with determination of DHEA-S by enzyme immunoassay (EIA bringing this saliva collection method into question. Because of the increasing popularity of salivary biomarker research, we sought to determine whether the cotton swab interferes with DHEA-S determination through EIA techniques. Findings Fifty-six healthy young adult men and women aged 18-30 years came to the lab in the morning (0800 hrs; 14 men, 14 women or late afternoon (1600 hrs; 14 men, 14 women and provided saliva samples via cotton Salivette and passive drool. Passive drool collection was taken first to minimize particle cross contamination from the cotton swab. Samples were assayed for DHEA-S in duplicate using a commercially available kit (DSL, Inc., Webster, TX. DHEA-S levels collected via Salivette and passive drool were positively correlated (r = + 0.83, p Conclusions Results suggest that DHEA-S can be measured accurately using passive drool or cotton Salivette collection methods. Results also suggest that DHEA-S levels change across the day and that future studies need to take this time of day difference into account when measuring DHEA-S.

  10. Informal caregivers and detection of delirium in postacute care: a correlational study of the confusion assessment method (CAM), confusion assessment method-family assessment method (CAM-FAM) and DSM-IV criteria.

    Science.gov (United States)

    Flanagan, Nina M; Spencer, Gale

    2016-09-01

    Delirium is a common, serious and potentially life-threatening syndrome affecting older adults. This syndrome continues to be under-recognised and under treated by healthcare professionals across all care settings. Older adults who develop delirium have poorer outcomes, higher mortality and higher care costs. The purposes of this study were to correlate the confusion assessment method-family assessment method and confusion assessment method in the detection of delirium in postacute care, to correlate the confusion assessment method-family assessment method and diagnostic and statistical manual of mental disorders text revision criteria in detection of delirium in postacute care, to determine the prevalence of delirium in postacute care elders and to describe the relationship of level of cognitive impairment and delirium in the postacute care setting. Implications for Practice Delirium is disturbing for patients and caregivers. Frequently . family members want to provide information about their loved one. The use of the CAM-FAM and CAM can give a more definitive determination of baseline status. Frequent observations using both instruments may lead to better recognition of delirium and implementation of interventions to prevent lasting sequelae. Descriptive studies determined the strengths of relationship between the confusion assessment method, confusion assessment method-family assessment method, Mini-Cog and diagnostic and statistical manual of mental disorders text revision criteria in detection of delirium in the postacute care setting. Prevalence of delirium in this study was 35%. The confusion assessment method-family assessment method highly correlates with the confusion assessment method and diagnostic and statistical manual of mental disorders text revision criteria for detecting delirium in older adults in the postacute care setting. Persons with cognitive impairment are more likely to develop delirium. Family members recognise symptoms of delirium when

  11. A comparison of confidence interval methods for the intraclass correlation coefficient in community-based cluster randomization trials with a binary outcome.

    Science.gov (United States)

    Braschel, Melissa C; Svec, Ivana; Darlington, Gerarda A; Donner, Allan

    2016-04-01

    Many investigators rely on previously published point estimates of the intraclass correlation coefficient rather than on their associated confidence intervals to determine the required size of a newly planned cluster randomized trial. Although confidence interval methods for the intraclass correlation coefficient that can be applied to community-based trials have been developed for a continuous outcome variable, fewer methods exist for a binary outcome variable. The aim of this study is to evaluate confidence interval methods for the intraclass correlation coefficient applied to binary outcomes in community intervention trials enrolling a small number of large clusters. Existing methods for confidence interval construction are examined and compared to a new ad hoc approach based on dividing clusters into a large number of smaller sub-clusters and subsequently applying existing methods to the resulting data. Monte Carlo simulation is used to assess the width and coverage of confidence intervals for the intraclass correlation coefficient based on Smith's large sample approximation of the standard error of the one-way analysis of variance estimator, an inverted modified Wald test for the Fleiss-Cuzick estimator, and intervals constructed using a bootstrap-t applied to a variance-stabilizing transformation of the intraclass correlation coefficient estimate. In addition, a new approach is applied in which clusters are randomly divided into a large number of smaller sub-clusters with the same methods applied to these data (with the exception of the bootstrap-t interval, which assumes large cluster sizes). These methods are also applied to a cluster randomized trial on adolescent tobacco use for illustration. When applied to a binary outcome variable in a small number of large clusters, existing confidence interval methods for the intraclass correlation coefficient provide poor coverage. However, confidence intervals constructed using the new approach combined with Smith

  12. Two-Dimensional UV Absorption Correlation Spectroscopy as a Method for the Detection of Thiamethoxam Residue in Tea

    Science.gov (United States)

    Zhang, J.; Zhao, Zh.; Wang, L.; Zhu, X.; Shen, L.; Yu, Y.

    2015-05-01

    Two-dimensional correlation spectroscopy (2D-COS) combined with UV absorption spectroscopy was evaluated as a technique for the identification of spectral regions associated with the residues of thiamethoxam in tea. There is only one absorption peak at 275 nm in the absorption spectrum of a mixture of thiamethoxam and tea, which is the absorption peak of tea. Based on 2D-COS, the absorption peak of thiamethoxam at 250 nm is extracted from the UV spectra of the mixture. To determine the residue of thiamethoxam in tea, 250 nm is selected as the measured wavelength, at which the fitting result is as follows: the residual sum of squares is 0.01375, standard deviation R2 is 0.99068, and F value is 426. Statistical analysis shows that there is a significant linear relationship between the concentration of thiamethoxam in tea and the absorbance at 250 nm in the UV spectra of the mixture. Moreover, the average prediction error is 0.0033 and the prediction variance is 0.1654, indicating good predictive result. Thus, the UV absorption spectrum can be used as a measurement method for rapid detection of thiamethoxam residues in tea.

  13. Deformation behavior of lead zirconate titanate ceramics under uniaxial compression measured by the digital image correlation method

    Science.gov (United States)

    Chen, Di; Carter, Emma; Kamlah, Marc

    2016-09-01

    The deformation behavior of lead zirconate titanate bulk ceramic specimen under uniaxial compression was monitored by the digital image correlation method and the homogeneity of the deformation was discussed. Combined with using a Sawyer-Tower circuit, the depolarization curve was also obtained. Because of the friction at both the top and bottom surfaces of the lead zirconate titanate ceramic specimen, the distribution of deformation under large uniaxial compressive stresses usually shows a barrel shape. By focusing on correspondingly selected regions of interest and calculating the values of strain components there, the barreling behavior was proved. This barreling behavior is due to elastic strains, in the first place, while the remnant strains are less affected by this phenomenon. All these findings are the experimental justifications for the selection of an aspect ratio of 3:1 for our specimens, where only the central cubic region of a specimen represents the desired purely uniaxial stress state. Only from this region, true uniaxial stress-strain results can be obtained to develop constitutive models.

  14. Correlation of Chlamydia and Chlamydophila spp. IgG and IgM antibodies by microimmunofluorescence with antigen detection methods.

    Science.gov (United States)

    She, Rosemary C; Welch, Ryan; Wilson, Andrew R; Davis, David; Litwin, Christine M

    2011-01-01

    Correlation of serologic titers for Chlamydia trachomatis with other tests has been based on direct fluorescence antibody (DFA) testing and culture, but not on nucleic acid-based tests that are used for screening. We retrospectively reviewed the specificity of antibodies against C. trachomatis, Chlamydia psittaci, and Chlamydophila pneumoniae by microimmunofluorescence (MIF) when compared with DFA, culture, nucleic acid probe, and transcription-mediated amplification. Over a 6-year period, 226 cases had both MIF and one of these other methods performed for comparison. Agreement between C. trachomatis antigen or nucleic acid detection and MIF results was 87% (197/226). C. trachomatis serology had a negative predictive value of 98%, and 10.6% of cases were positive by serology and negative by antigen testing. Of the 13 patients who had a positive C. trachomatis antigen or nucleic acid test result, 9 had IgG and/or IgM titers highest against C. trachomatis, 3 had IgG titers highest against C. pneumoniae, and 1 had undetectable titers for the three chlamydial species. Twenty-five patients had positive IgG and/or IgM titers to C. trachomatis but negative antigen test results. Serologic testing can increase the sensitivity of detecting C. trachomatis infections.

  15. Density functional theory embedding for correlated wavefunctions: Improved methods for open-shell systems and transition metal complexes

    CERN Document Server

    Goodpaster, Jason D; Manby, Frederick R; Miller, Thomas F

    2012-01-01

    Density functional theory (DFT) embedding provides a formally exact framework for interfacing correlated wave-function theory (WFT) methods with lower-level descriptions of electronic structure. Here, we report techniques to improve the accuracy and stability of WFT-in-DFT embedding calculations. In particular, we develop spin-dependent embedding potentials in both restricted and unrestricted orbital formulations to enable WFT-in-DFT embedding for open-shell systems, and we develop an orbital-occupation-freezing technique to improve the convergence of optimized effective potential (OEP) calculations that arise in the evaluation of the embedding potential. The new techniques are demonstrated in applications to the van-der-Waals-bound ethylene-propylene dimer and to the hexaaquairon(II) transition-metal cation. Calculation of the dissociation curve for the ethylene-propylene dimer reveals that WFT-in-DFT embedding reproduces full CCSD(T) energies to within 0.1 kcal/mol at all distances, eliminating errors in th...

  16. A new method to evaluate the similarity of chromatographic fingerprints: weighted pearson product-moment correlation coefficient.

    Science.gov (United States)

    Liu, Yongsuo; Meng, Qinghua; Chen, Rong; Wang, Jiansong; Jiang, Shumin; Hu, Yuzhu

    2004-01-01

    The Pearson product-moment correlation coefficient is being used to evaluate the similarity of the high-performance liquid chromatographic fingerprints of traditional Chinese medicine (TCM) in China. It is confirmed that a large range of peak areas produced the wrong results. A new algorithm concerning weighted Pearson product-moment correlation coefficient is proposed in this article. The results for both real cases and simulated data sets show that the weighted Pearson product-moment correlation coefficients allow relatively larger differences for large values, smaller differences for small values, and more reliable results than the unweighted Pearson product-moment correlation coefficients. Weight selection depends on the specific scientific problem.

  17. Correlation of trans-Lycopene Measurements by the HPLC Method with the Optothermal and Photoacoustic Signals and the Color Readings of Fresh Tomato Homogenates.

    Science.gov (United States)

    Bicanic, Dane; Dimitrovski, Darko; Luterotti, Svjetlana; Marković, Ksenija; van Twisk, Charlotte; Buijnsters, Josephus G; Dóka, Otto

    2010-03-01

    The trans-lycopene content of fresh tomato homogenates was assessed by means of the laser photoacoustic spectroscopy, the laser optothermal window, micro-Raman spectroscopy, and colorimetry; none of these methods require the extraction from the product matrix prior to the analysis. The wet chemistry method (high-performance liquid chromatography) was used as the absolute quantitative method. Analytical figures of merit for all methods were compared statistically; best linear correlation was achieved for the chromaticity index a* and chroma C*.

  18. Effects of tissue mechanical and acoustic anisotropies on the performance of a cross-correlation-based ultrasound strain imaging method

    Science.gov (United States)

    Li, He; Lee, Wei-Ning

    2017-02-01

    The anisotropic mechanical properties (mechanical anisotropy) and view-dependent ultrasonic backscattering (acoustic anisotropy) of striated muscle due to the underlying myofiber arrangement have been well documented, but whether they impact on ultrasound strain imaging (USI) techniques remains unclear. The aim of this study was therefore to investigate the performance of a cross-correlation-based two-dimensional (2D) USI method in anisotropic media under controlled quasi-static compression in silico and in vitro. First, synthetic pre- and post-deformed 2D radiofrequency images of anisotropic phantoms were simulated in two scenarios to examine the individual effect of the mechanical and acoustic anisotropies on strain estimation. In the first scenario, the phantom was defined to be transversely isotropic with the scatterer amplitudes following a zero-mean Gaussian distribution, while in the second scenario, the phantom was defined to be mechanically isotropic with Gaussian distributed scatterer amplitudes correlated along the principal directions of pre-defined fibers. These two anisotropies were then jointly incorporated into the ultrasound image simulation model with additional depth-dependent attenuation. Three imaging planes—the fiber plane with the fiber direction perpendicular to the ultrasound beam (TISperp_fb), the fiber plane with the fiber direction parallel to the beam (TISpara), and the transverse fiber plane (TISperp_cfb)—were studied. The absolute relative error (ARE) of the lateral strain estimates in TISperp_fb (20.99  ±  15.65%) was much higher than that in TISperp_cfb (4.14  ±  3.17%). The ARE in TISpara was unavailable owing to the large spatial extent of false peaks. The effect of tissue anisotropy on the performance of the 2D USI was further confirmed in an in vitro porcine skeletal muscle phantom. The best in-plane strain quality was again shown in TISperp_cfb (elastographic signal-to-noise ratio, or SNRe:  >25 d

  19. Correlation of Parathormone and the Serum Values of Acidum Uricum with Calcium Nephrolithiasis Examined by Three Different Methods of Diagnostics

    Science.gov (United States)

    Milicevic, Snjezana; Bijelic, Radojka; Jakovljevic, Branislava

    2015-01-01

    Introduction. Urolithiasis is a multifactorial disease. Changes in social and economic living conditions have generated changes in chemical composition of urolith too. Although calcium is a predominant crystalline constituent of kidney stones in 80% of cases, metabolic disorders are not the main reason for their formation. Hyperparathyroidism may be a cause of occurrence of calcium lithiasis, however, the biggest number of its occurrence is not a consequence of elevated values of parathormone. Acid uric has a pervasive presence in all body fluids. The serum level of acid uric is determined by its rate of synthesis, rate of excretion by kidney and gastrointestinal tract, and metabolism. Goal. The goal of our study is to determine a correlation of calcium lithiasis of the upper part of the urinary tract with the parathormone values and the concomitant values of acidum uricum. Material and methods. The study was prospective and included 120 patients with calcium lithiasis of the upper part of urinary tract, divided in three age categories, 20-40 years, 40-60 years and older than 60 years. The diagnosis of calcium lithiasis of the upper part of the urinary tract was made on the basis of urinary tract ultrasonography, and kidney-ureter-bladder radiography (KUB) /intravenous urography (IVU), urine culture and chemical analysis of stone with patients who had a spontaneous emission of stone or following some of the methods for active removal of stone; with some patients non-contrast (NCCT) was carried out too. All patients were subjected to the laboratory analysis of the serum level of acidum uricum and parathormone. Results. With observed 120 patients suffering from calcium urolithiasis, who belonged to adult population, no patient had an elevated value of parathormone, while three patients (2.5%) had the values of acidum uricum higher than the reference values. The average value (for both parameters) was the lowest with the youngest patients and vice versa, and only in

  20. A fast and accurate method for the simulation of the diffusing temporal light correlation in multi-layered turbid media

    Institute of Scientific and Technical Information of China (English)

    LUO Bin; LI Jun; HE Sai-ling

    2005-01-01

    Monte Carlo simulation of the diffusing temporal light correlation in a multi-layered turbid medium is considered.A straightforward formula is introduced to calculate accurately and efficiently the autocorrelation function at any detector position.The simulation results are in an excellent agreement with an analytical solution of the correlation diffusion equation.

  1. A novel method for measurement of the spin correlation function for relativistic electron pairs produced in Møller scattering

    Science.gov (United States)

    Bodek, K.; Kępka, D.; Rozpędzik, D.; Zejma, J.; Kozela, A.

    2017-04-01

    A self-calibrating double-Mott polarimeter is proposed for measurement of the spin correlation function of relativistic electron pairs produced in Møller scattering. The polarization of outgoing electrons (appearing when the beam is polarized) is utilized for calibration of effective analyzing powers in the secondary Mott scattering used for spin analysis. The experiment will measure the newly introduced relative spin correlation function. This new observable can be measured with a significantly better accuracy than the regular spin correlation function in a small scale experiment. It is shown that both the spin correlation function and the relative spin correlation function are theoretically equivalent. A specific experimental data analysis scenario is proposed, which effectively eliminates the systematic effects related to the imperfect geometry and detector efficiency.

  2. 基于几何法的雷达与ESM航迹关联算法%Radar-ESM Track Correlation Based on Geometric Method

    Institute of Scientific and Technical Information of China (English)

    陈中华; 王国宏; 刘德浩; 谭顺成

    2012-01-01

    为解决雷达与ESM航迹关联门限的不确定性,提出了基于几何法的雷达与ESM航迹关联算法.该算法根据雷达与ESM的几何位置建立航迹粗关联函数,并利用航迹的历史信息建立航迹关联代价矩阵,通过代价最小实现航迹关联.仿真结果表明,该算法具有很好的关联性能.%In order to deal with the uncertainty thresholds of Radar-ESM ( Electronic Support Measures) correlation, an Radar-ESM correlation mode based on geometric method was proposed. Firstly, a coarse correlation function was built up based on the geometric position of radar and ESM. Then,a cost correlation matrix was set up by accumulating the historical information of the coarse correlation. Thus the track correlation was realized by finding the minimum cost of cost matrix. Finally, the correlation method proposed was verified by Monte Carlo simulation.

  3. COBAS® TaqMan® MTB, smear positivity grade and MGIT culture; correlation analyses of three methods for bacillary quantification.

    Science.gov (United States)

    Chikamatsu, Kinuyo; Aono, Akio; Kato, Tomoko; Takaki, Akiko; Yamada, Hiroyuki; Sasaki, Yuka; Izumi, Kiyohiko; Yi, Lina; Mitarai, Satoshi

    2016-01-01

    We investigated the correlation between the cycle threshold (Ct) value of the COBAS(®) TaqMan(®) MTB (TaqMan MTB), the mycobacterial smear positivity grade, and the time to detection (TTD) in the Mycobacteria Growth Indicator Tube (MGIT) for quantification of Mycobacterium tuberculosis (MTB). For 57 sputum samples, significant correlations were observed between the Ct value, the smear positivity grade, and the MGIT TTD (Spearman's rank correlation coefficient: r(s) = -0.940, P real-time PCR system, for diagnostic samples.

  4. Correlations among different markers determined by immunochemical methods used for the diagnosis and monitoring of intact immunoglobulin multiple myeloma cases.

    Science.gov (United States)

    Dogaru, Monica; Lazăr, Veronica; Coriu, Daniel

    2012-01-01

    The purpose of this study was to determine the correlations between the concentration of free light chains (kappa, lambda and ratio kappa/lambda) and two other markers, M- protein and pathological total intact immunoglobulin in four groups of patients with intact immunoglobulin multiple myeloma (IIMM) at the diagnosis and during the treatment. In this study 354 samples coming from 46 patients with IIMM were assayed, out of which: 19, IgGkappa; 13, IgGlambda; 7, IgAkappa; 7, IgAlambda. At the diagnosis, immunofixation was positive in all samples and serum protein electrophoresis quantified M- protein for all patients. Free light chains concentrations were abnormal in 92.25% of patients with concentrations above the reference ranges in all patients with IgGkappa and IgAkappa MM. The intact immunoglobulins were elevated in 83.12% of cases. Pearson correlation coefficient showed correlations among the free light chains serum levels (kappa, lambda and ratio kappa/lambda), M- protein and intact immunoglobulins in two groups with IIMM (IgGlambda, IgAlambda). Spearman correlation coefficient values analysis showed that there is a good correlation between M-protein and FLCs (kappa, lambda and ratio kappa/lambda) in three patient groups (IgGkappa, IgGlambda and IgAlambda), excepting IgAkappa myeloma group where the correlation was insignificant. Regarding the intact immunoglobulin, Spearman coefficient showed significant correlations with FLCs concentrations in two groups (IgGlambda and IgAlambda) and an insignificant correlation in the group with IgGkappa MM. For the group of patients with IgAkappa myeloma, the Spearman coefficient showed that IgA concentrations did not correlate with the concentrations of FLCs. The individual correlation (for each patient) among FLCs, M- protein and intact immunoglobulins in 8 patients with IgGkappa IIMM proved to be more significant as compared with the degree of correlation established for the entire group of patients among these markers

  5. Experimental study of the temperature distribution in the TRIGA IPR-R1 Brazilian research reactor; Investigacao experimental da distribuicao de temperaturas no reator nuclear de pesquisa TRIGA IPR-R1

    Energy Technology Data Exchange (ETDEWEB)

    Mesquita, Amir Zacarias

    2005-07-01

    The TRIGA-IPR-R1 Research Nuclear Reactor has completed 44 years in operation in November 2004. Its initial nominal thermal power was 30 kW. In 1979 its power was increased to 100 kW by adding new fuel elements to the reactor. Recently some more fuel elements were added to the core increasing the power to 250 kW. The TRIGA-IPR-R1 is a pool type reactor with a natural circulation core cooling system. Although the large number of experiments had been carried out with this reactor, mainly on neutron activation analysis, there is not many data on its thermal-hydraulics processes, whether experimental or theoretical. So a number of experiments were carried out with the measurement of the temperature inside the fuel element, in the reactor core and along the reactor pool. During these experiments the reactor was set in many different power levels. These experiments are part of the CDTN/CNEN research program, and have the main objective of commissioning the TRIGA-IPR-R1 reactor for routine operation at 250 kW. This work presents the experimental and theoretical analyses to determine the temperature distribution in the reactor. A methodology for the calibration and monitoring the reactor thermal power was also developed. This methodology allowed adding others power measuring channels to the reactor by using thermal processes. The fuel thermal conductivity and the heat transfer coefficient from the cladding to the coolant were also experimentally valued. lt was also presented a correlation for the gap conductance between the fuel and the cladding. The experimental results were compared with theoretical calculations and with data obtained from technical literature. A data acquisition and processing system and a software were developed to help the investigation. This system allows on line monitoring and registration of the main reactor operational parameters. The experiments have given better comprehension of the reactor thermal-fluid dynamics and helped to develop numerical

  6. Orbital-dependent exchange-correlation functionals in density-functional theory realized by the FLAPW method

    Energy Technology Data Exchange (ETDEWEB)

    Betzinger, Markus

    2011-12-14

    In this thesis, we extended the applicability of the full-potential linearized augmented-plane-wave (FLAPW) method, one of the most precise, versatile and generally applicable electronic structure methods for solids working within the framework of density-functional theory (DFT), to orbital-dependent functionals for the exchange-correlation (xc) energy. Two different schemes that deal with orbital-dependent functionals, the Kohn-Sham (KS) and the generalized Kohn-Sham (gKS) formalism, have been realized. Hybrid functionals, combining some amount of the orbital-dependent exact exchange energy with local or semi-local functionals of the density, are implemented within the gKS scheme. We work in particular with the PBE0 hybrid of Perdew, Burke, and Ernzerhof. Our implementation relies on a representation of the non-local exact exchange potential - its calculation constitutes the most time consuming step in a practical calculation - by an auxiliary mixed product basis (MPB). In this way, the matrix elements of the Hamiltonian corresponding to the non-local potential become a Brillouin-zone (BZ) sum over vector-matrix-vector products. Several techniques are developed and explored to further accelerate our numerical scheme. We show PBE0 results for a variety of semiconductors and insulators. In comparison with experiment, the PBE0 functional leads to improved band gaps and an improved description of localized states. Even for the ferromagnetic semiconductor EuO with localized 4f electrons, the electronic and magnetic properties are correctly described by the PBE0 functional. Subsequently, we discuss the construction of the local, multiplicative exact exchange (EXX) potential from the non-local, orbital-dependent exact exchange energy. For this purpose we employ the optimized effective potential (OEP) method. Central ingredients of the OEP equation are the KS wave-function response and the single-particle density response function. We show that a balance between the LAPW

  7. Measurement of multi-particle azimuthal correlations with the subevent cumulant method in $pp$ and $p$+Pb collisions with the ATLAS detector at the LHC

    CERN Document Server

    Aaboud, Morad; ATLAS Collaboration; Abbott, Brad; Abdinov, Ovsat; Abeloos, Baptiste; Abidi, Syed Haider; AbouZeid, Ossama; Abraham, Nicola; Abramowicz, Halina; Abreu, Henso; Abreu, Ricardo; Abulaiti, Yiming; Acharya, Bobby Samir; Adachi, Shunsuke; Adamczyk, Leszek; Adelman, Jahred; Adersberger, Michael; Adye, Tim; Affolder, Tony; Afik, Yoav; Agatonovic-Jovin, Tatjana; Agheorghiesei, Catalin; Aguilar-Saavedra, Juan Antonio; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Akatsuka, Shunichi; Akerstedt, Henrik; Åkesson, Torsten Paul Ake; Akilli, Ece; Akimov, Andrei; Alberghi, Gian Luigi; Albert, Justin; Albicocco, Pietro; Alconada Verzini, Maria Josefina; Alderweireldt, Sara; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexopoulos, Theodoros; Alhroob, Muhammad; Ali, Babar; Aliev, Malik; Alimonti, Gianluca; Alison, John; Alkire, Steven Patrick; Allbrooke, Benedict; Allen, Benjamin William; Allport, Phillip; Aloisio, Alberto; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Alshehri, Azzah Aziz; Alstaty, Mahmoud; Alvarez Gonzalez, Barbara; Άlvarez Piqueras, Damián; Alviggi, Mariagrazia; Amadio, Brian Thomas; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Amor Dos Santos, Susana Patricia; Amoroso, Simone; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, John Kenneth; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Angelidakis, Stylianos; Angelozzi, Ivan; Angerami, Aaron; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antel, Claire; Antonelli, Mario; Antonov, Alexey; Antrim, Daniel Joseph; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Arabidze, Giorgi; Arai, Yasuo; Araque, Juan Pedro; Araujo Ferraz, Victor; Arce, Ayana; Ardell, Rose Elisabeth; Arduh, Francisco Anuar; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Armitage, Lewis James; Arnaez, Olivier; Arnold, Hannah; Arratia, Miguel; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Artz, Sebastian; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Augsten, Kamil; Avolio, Giuseppe; Axen, Bradley; Ayoub, Mohamad Kassem; Azuelos, Georges; Baas, Alessandra; Baca, Matthew John; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Bagnaia, Paolo; Bahmani, Marzieh; Bahrasemani, Sina; Baines, John; Bajic, Milena; Baker, Oliver Keith; Bakker, Pepijn Johannes; Baldin, Evgenii; Balek, Petr; Balli, Fabrice; Balunas, William Keaton; Banas, Elzbieta; Bandyopadhyay, Anjishnu; Banerjee, Swagato; Bannoura, Arwa A E; Barak, Liron; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisits, Martin-Stefan; Barkeloo, Jason Tyler Colt; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska-Blenessy, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barranco Navarro, Laura; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Basalaev, Artem; Bassalat, Ahmed; Bates, Richard; Batista, Santiago Juan; Batley, Richard; Battaglia, Marco; Bauce, Matteo; Bauer, Florian; Bawa, Harinder Singh; Beacham, James; Beattie, Michael David; Beau, Tristan; Beauchemin, Pierre-Hugues; Bechtle, Philip; Beck, Hans~Peter; Beck, Helge Christoph; Becker, Kathrin; Becker, Maurice; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bednyakov, Vadim; Bedognetti, Matteo; Bee, Christopher; Beermann, Thomas; Begalli, Marcia; Begel, Michael; Behr, Janna Katharina; Bell, Andrew Stuart; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belotskiy, Konstantin; Beltramello, Olga; Belyaev, Nikita; Benary, Odette; Benchekroun, Driss; Bender, Michael; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez, Jose; Benjamin, Douglas; Benoit, Mathieu; Bensinger, James; Bentvelsen, Stan; Beresford, Lydia; Beretta, Matteo; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Beringer, Jürg; Berlendis, Simon; Bernard, Nathan Rogers; Bernardi, Gregorio; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertoli, Gabriele; Bertram, Iain Alexander; Bertsche, Carolyn; Bertsche, David; Besjes, Geert-Jan; Bessidskaia Bylund, Olga; Bessner, Martin Florian; Besson, Nathalie; Bethani, Agni; Bethke, Siegfried; Betti, Alessandra; Bevan, Adrian John; Beyer, Julien-christopher; Bianchi, Riccardo-Maria; Biebel, Otmar; Biedermann, Dustin

    2017-01-01

    A detailed study of multi-particle azimuthal correlations is presented using $pp$ data at $\\sqrt{s}=5.02$ and 13 TeV, and $p$+Pb data at $\\sqrt{s_{\\rm{NN}}}=5.02$ TeV, recorded with the ATLAS detector at the LHC. The azimuthal correlations are probed using four-particle cumulants $c_{n}\\{4\\}$ and flow coefficients $v_n\\{4\\}=(-c_{n}\\{4\\})^{1/4}$ for $n=2$ and 3, with the goal of extracting long-range multi-particle azimuthal correlation signals and suppressing the short-range correlations. The values of $c_{n}\\{4\\}$ are obtained as a function of the average number of charged particles per event, $\\left\\langle N_{\\rm{ch}} \\right\\rangle$, using the recently proposed two-subevent and three-subevent cumulant methods, and compared with results obtained with the standard cumulant method. The three-subevent method is found to be least sensitive to short-range correlations, which originate mostly from jets with a positive contribution to $c_{n}\\{4\\}$. The three-subevent method gives a negative $c_{2}\\{4\\}$, and theref...

  8. Investigation on the of effect of self assembling molecules on the corrosion resistance of the 1050 aluminium alloy; Investigacao do efeito de moleculas auto-organizaveis na resistencia a corrosao da liga de aluminio 1050

    Energy Technology Data Exchange (ETDEWEB)

    Szurkalo, Margarida

    2009-07-01

    Surface treatments are widely used to increase the corrosion resistance of metallic materials. Specifically for aluminum and aluminum alloys, treatment with hexavalent chromium is one of the most used, due to its efficiency and ease of application. However, because of environmental restrictions and the high cost involved in the treatments of waste generated in this process, alternative methods for its replacement are necessary. In this context, this study investigated the effect of the surface treatment with self-assembling molecules (SAM) based on phosphonate compounds on the corrosion of the 1050 aluminum alloy. The conditions adopted for the SAM treatment were determined by conductivity and contact angle measurements, besides electrochemical experiments. Electrochemical techniques, specifically: measurement of the open circuit potential (OCP) variation with time, electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization curves were used to evaluate the corrosion resistance of the 1050 aluminum alloy exposed to SAM treatment The experimental impedance diagrams were interpreted using equivalent electrical circuit models that simulate film that is formed on the alloy surface. The results of the samples treated with SAM were compared with those of samples either without any treatment or treated with chromatizing conversion coating with Cr(VI) and showed that the first treatment significantly increased the corrosion resistance of the aluminum alloy and approached that of chromatizing with Cr(VI) process. (author)

  9. Advanced optical correlation and digital methods for pattern matching—50th anniversary of Vander Lugt matched filter

    Science.gov (United States)

    Millán, María S.

    2012-10-01

    On the verge of the 50th anniversary of Vander Lugt’s formulation for pattern matching based on matched filtering and optical correlation, we acknowledge the very intense research activity developed in the field of correlation-based pattern recognition during this period of time. The paper reviews some domains that appeared as emerging fields in the last years of the 20th century and have been developed later on in the 21st century. Such is the case of three-dimensional (3D) object recognition, biometric pattern matching, optical security and hybrid optical-digital processors. 3D object recognition is a challenging case of multidimensional image recognition because of its implications in the recognition of real-world objects independent of their perspective. Biometric recognition is essentially pattern recognition for which the personal identification is based on the authentication of a specific physiological characteristic possessed by the subject (e.g. fingerprint, face, iris, retina, and multifactor combinations). Biometric recognition often appears combined with encryption-decryption processes to secure information. The optical implementations of correlation-based pattern recognition processes still rely on the 4f-correlator, the joint transform correlator, or some of their variants. But the many applications developed in the field have been pushing the systems for a continuous improvement of their architectures and algorithms, thus leading towards merged optical-digital solutions.

  10. Diagnostics of hemangioma by the methods of correlation and fractal analysis of laser microscopic images of blood plasma

    Science.gov (United States)

    Boychuk, T. M.; Bodnar, B. M.; Vatamanesku, L. I.

    2012-01-01

    For the first time the complex correlation and fractal analysis was used for the investigation of microscopic images of both tissue images and hemangioma liquids. It was proposed a physical model of description of phase distributions formation of coherent radiation, which was transformed by optical anisotropic biological structures. The phase maps of laser radiation in the boundary diffraction zone were used as the main information parameter. The results of investigating the interrelation between the values of correlation (correlation area, asymmetry coefficient and autocorrelation function excess) and fractal (dispersion of logarithmic dependencies of power spectra) parameters are presented. They characterize the coordinate distributions of phase shifts in the points of laser images of histological sections of hemangioma, hemangioma blood smears and blood plasma with vascular system pathologies. The diagnostic criteria of hemangioma nascency are determined.

  11. In-pipe leak detection by Minimum Residual complexity: A Robust time Delay Estimation method against correlated noise

    CERN Document Server

    Ahmadi, A M; Bahrampour, A R; Ravanbod, H

    2013-01-01

    In this work, the residual complexity (RC) similarity measure, is employed for time delay estimation (TDE) in gas pipe leak localization. The result of TDE by RC is compared with those of Cross Correlation(CC) and Mutual Information(MI) similarity measures based on our experimental data. The comparison confirms the advantages of RC relative to CC and MI, in robustness against both correlated noises and reduction of number of samples. These advantages originate from not only its mathematical nature of RC similarity measure which considers interdependency but also from broadband frequency of acoustic waves propagating during gas pipes.

  12. Neural Correlates of Biased Responses: The Negative Method Effect in the Rosenberg Self-Esteem Scale Is Associated with Right Amygdala Volume.

    Science.gov (United States)

    Wang, Yinan; Kong, Feng; Huang, Lijie; Liu, Jia

    2016-10-01

    Self-esteem is a widely studied construct in psychology that is typically measured by the Rosenberg Self-Esteem Scale (RSES). However, a series of cross-sectional and longitudinal studies have suggested that a simple and widely used unidimensional factor model does not provide an adequate explanation of RSES responses due to method effects. To identify the neural correlates of the method effect, we sought to determine whether and how method effects were associated with the RSES and investigate the neural basis of these effects. Two hundred and eighty Chinese college students (130 males; mean age = 22.64 years) completed the RSES and underwent magnetic resonance imaging (MRI). Behaviorally, method effects were linked to both positively and negatively worded items in the RSES. Neurally, the right amygdala volume negatively correlated with the negative method factor, while the hippocampal volume positively correlated with the general self-esteem factor in the RSES. The neural dissociation between the general self-esteem factor and negative method factor suggests that there are different neural mechanisms underlying them. The amygdala is involved in modulating negative affectivity; therefore, the current study sheds light on the nature of method effects that are related to self-report with a mix of positively and negatively worded items. © 2015 Wiley Periodicals, Inc.

  13. Molecular dynamics simulation and vibrational spectroscopy of molecules (Ⅰ)——A method of internal coordinate correlation for band assignment

    Institute of Scientific and Technical Information of China (English)

    杨小震

    1995-01-01

    A method of simulation of vibrational spectra by using the "internal coordinatecorrelation" based on molecular dynamics algorithms and auto-correlation function has been developed.The in-ternal coordinates,such as bond stretching,bond angle bending,out-of-plane bending and torsion,are treatedas the dynamic variables to obtain a density spectrum or the "internal coordinate correlation" spectrum Theadvantages of this method are as follows:i)it is easier to assign vibration modes for the density spectra;ii)itsimply connects the Fourier transformed "internal coordinate correlation" function to the eigenvectors innormal coordinate analysis;iii)it is a basis for simulating IR and Raman active spectra of a large molecularsystem.

  14. Ab initio-driven nuclear energy density functional method. A proposal for safe/correlated/improvable parametrizations of the off-diagonal EDF kernels

    Energy Technology Data Exchange (ETDEWEB)

    Duguet, T. [IRFU/Service de Physique Nucleaire, CEA, Centre de Saclay, Gif-sur-Yvette (France); Instituut voor Kern- en Stralingsfysica, KU Leuven, Leuven (Belgium); Michigan State University, National Superconducting Cyclotron Laboratory and Department of Physics and Astronomy, East Lansing, MI (United States); Bender, M. [Centre d' Etudes Nucleaires de Bordeaux Gradignan, Universite Bordeaux, UMR5797, Gradignan (France); Centre d' Etudes Nucleaires de Bordeaux Gradignan, CNRS/IN2P3, UMR5797, Gradignan (France); Ebran, J.P. [CEA, DAM, DIF, Arpajon (France); Lesinski, T.; Soma, V. [IRFU/Service de Physique Nucleaire, CEA, Centre de Saclay, Gif-sur-Yvette (France)

    2015-12-15

    This programmatic paper lays down the possibility to reconcile the necessity to resum many-body correlations into the energy kernel with the fact that safe multi-reference energy density functional (EDF) calculations cannot be achieved whenever the Pauli principle is not enforced, as is for example the case when many-body correlations are parametrized under the form of empirical density dependencies. Our proposal is to exploit a newly developed ab initio many-body formalism to guide the construction of safe, explicitly correlated and systematically improvable parametrizations of the off-diagonal energy and norm kernels that lie at the heart of the nuclear EDF method. The many-body formalism of interest relies on the concepts of symmetry breaking and restoration that have made the fortune of the nuclear EDF method and is, as such, amenable to this guidance. After elaborating on our proposal, we briefly outline the project we plan to execute in the years to come. (orig.)

  15. A Small Leak Detection Method Based on VMD Adaptive De-Noising and Ambiguity Correlation Classification Intended for Natural Gas Pipelines

    Directory of Open Access Journals (Sweden)

    Qiyang Xiao

    2016-12-01

    Full Text Available In this study, a small leak detection method based on variational mode decomposition (VMD and ambiguity correlation classification (ACC is proposed. The signals acquired from sensors were decomposed using the VMD, and numerous components were obtained. According to the probability density function (PDF, an adaptive de-noising algorithm based on VMD is proposed for noise component processing and de-noised components reconstruction. Furthermore, the ambiguity function image was employed for analysis of the reconstructed signals. Based on the correlation coefficient, ACC is proposed to detect the small leak of pipeline. The analysis of pipeline leakage signals, using 1 mm and 2 mm leaks, has shown that proposed detection method can detect a small leak accurately and effectively. Moreover, the experimental results have shown that the proposed method achieved better performances than support vector machine (SVM and back propagation neural network (BP methods.

  16. A Small Leak Detection Method Based on VMD Adaptive De-Noising and Ambiguity Correlation Classification Intended for Natural Gas Pipelines.

    Science.gov (United States)

    Xiao, Qiyang; Li, Jian; Bai, Zhiliang; Sun, Jiedi; Zhou, Nan; Zeng, Zhoumo

    2016-12-13

    In this study, a small leak detection method based on variational mode decomposition (VMD) and ambiguity correlation classification (ACC) is proposed. The signals acquired from sensors were decomposed using the VMD, and numerous components were obtained. According to the probability density function (PDF), an adaptive de-noising algorithm based on VMD is proposed for noise component processing and de-noised components reconstruction. Furthermore, the ambiguity function image was employed for analysis of the reconstructed signals. Based on the correlation coefficient, ACC is proposed to detect the small leak of pipeline. The analysis of pipeline leakage signals, using 1 mm and 2 mm leaks, has shown that proposed detection method can detect a small leak accurately and effectively. Moreover, the experimental results have shown that the proposed method achieved better performances than support vector machine (SVM) and back propagation neural network (BP) methods.

  17. The intraclass correlation coefficient applied for evaluation of data correction, labeling methods and rectal biopsy sampling in DNA microarray experiments

    NARCIS (Netherlands)

    Pellis, E.P.M.; Franssen-Hal, van N.L.W.; Burema, J.; Keijer, J.

    2003-01-01

    We show that the intraclass correlation coefficient (ICC) can be used as a relatively simple statistical measure to assess methodological and biological variation in DNA microarray analysis. The ICC is a measure that determines the reproducibility of a variable, which can easily be calculated from a

  18. Lack of correlation between constitutive and induced resistance to a herbivore in crucifer plants: real or flawed by experimental methods?

    NARCIS (Netherlands)

    Zhang, P.J.; Shu, J.P.; Wu, Z.Y.; Dicke, M.; Liu, S.S.

    2009-01-01

    The correlation between constitutive and induced resistance to herbivores in plants has long been of interest to evolutionary biologists, and various approaches to determining levels of resistance have been used in this field of research. In this study, we examined the relationship between constitut

  19. Method and apparatus for a single channel digital communications system. [synchronization of received PCM signal by digital correlation with reference signal

    Science.gov (United States)

    Couvillon, L. A., Jr.; Carl, C.; Goldstein, R. M.; Posner, E. C.; Green, R. R. (Inventor)

    1973-01-01

    A method and apparatus are described for synchronizing a received PCM communications signal without requiring a separate synchronizing channel. The technique provides digital correlation of the received signal with a reference signal, first with its unmodulated subcarrier and then with a bit sync code modulated subcarrier, where the code sequence length is equal in duration to each data bit.

  20. On the theory of the proton dipolar-correlation effect as a method for investigation of segmental displacement in polymer melts

    Science.gov (United States)

    Lozovoi, A.; Petrova, L.; Mattea, C.; Stapf, S.; Rössler, E. A.; Fatkullin, N.

    2017-08-01

    A thorough theoretical description of the recently suggested method [A. Lozovoi et al. J. Chem. Phys. 144, 241101 (2016)] based on the proton NMR dipolar-correlation effect allowing for the investigation of segmental diffusion in polymer melts is presented. It is shown that the initial rise of the proton dipolar-correlation build-up function, constructed from Hahn Echo signals measured at times t and t/2, contains additive contributions from both inter- and intramolecular magnetic dipole-dipole interactions. The intermolecular contribution depends on the relative mean-squared displacement of polymer segments from different macromolecules, which provides an opportunity for an experimental study of segmental translational motions at the millisecond range that falls outside the typical range accessible by other methods, i.e., neutron scattering or NMR spin echo with the magnetic field gradients. A comparison with the other two proton NMR methods based on transverse spin relaxation phenomena, i.e., solid echo and double quantum resonance, shows that the initial rise of the build-up functions in all the discussed methods is essentially identical and differs only in numerical coefficients. In addition, it is argued that correlation functions constructed in the same manner as the dipolar-correlation build-up function can be applied for an experimental determination of a mean relaxation rate in the case of systems possessing multi-exponential magnetization decay.

  1. Accurate quantitative analysis of gold alloys using multi-pulse laser induced breakdown spectroscopy and a correlation-based calibration method

    Energy Technology Data Exchange (ETDEWEB)

    Galbacs, Gabor [Department of Inorganic and Analytical Chemistry, University of Szeged, 6720 Szeged, Dom ter 7. (Hungary)], E-mail: galbx@chem.u-szeged.hu; Jedlinszki, Nikoletta; Cseh, Gabor; Galbacs, Zoltan; Turi, Laszlo [Department of Inorganic and Analytical Chemistry, University of Szeged, 6720 Szeged, Dom ter 7. (Hungary)

    2008-05-15

    Multi-pulse laser induced breakdown spectroscopy (LIBS), in combination with the generalized linear correlation calibration method (GLCM), was applied to the quantitative analysis (fineness determination) of quaternary gold alloys. Accuracy and precision on the order of a few thousandths ( per mille ) was achieved. The analytical performance is directly comparable to that of the standard cupellation method (fire assay), but provides results within minutes and is virtually non-destructive, as it consumes only a few micrograms of the sample.

  2. Development of the Gamma-Gamma Perturbed Angular Correlation One-Detector Method for the Studies of the Physicochemical Properties of Matter

    CERN Document Server

    Filossofov, D V; Korolev, N A; Egorov, V G; Lebedev, N A; Akselrod, Z Z; Brockmann, J; Rösch, F

    2001-01-01

    A new method of the perturbed angular \\gamma\\gamma-correlation (PAC) measurements was developed using one detector only. For the perturbation factor quantification the relation of the summing peak composed of two cascade \\gamma-rays of study (the perturbation-affected parameter) to the summing peak composed of one \\gamma-ray and X-ray (the perturbation non-affected parameter) was used. This method was demonstrated for the ^{111}In and ^{111m}Cd radionuclides.

  3. Measurement of multi-particle azimuthal correlations with the subevent cumulant method in $pp$ and $p+$Pb collisions with the ATLAS detector

    CERN Document Server

    Zhou, Mingliang; The ATLAS collaboration

    2017-01-01

    The measurement of four-particle cumulant elliptic flow coefficients $c_{2}\\{4\\}$ and $v_{2}\\{4\\}$ are presented using $pp$ data at $\\sqrt{s}=5.02$ and $\\sqrt{s}=13$ TeV, and $p+$Pb data at $\\sqrt{s_{\\text{NN}}}=5.02$ TeV. The values of $c_{2}\\{4\\}$ are calculated using the standard cumulant method and recently proposed two subevent and three subevent methods. The two subevent method is found to be less sensitive to short-range correlations, and three subevent method further suppresses dijet correlations. The three subevent method gives a negative $c_{2}\\{4\\}$, and thus a well-defined $v_{2}\\{4\\}=(-c_{2}\\{4\\})^{1/4}$, in these collision systems. The magnitude of the $c_{2}\\{4\\}$ is found to be nearly independent of $\\langle N_{\\text{ch}}\\rangle$. Furthermore, $v_{2}\\{4\\}$ is found to be smaller than $v_{2}\\{2\\}$ measured using the two-particle correlation method, as expected for a long-range collective behavior. Following a recent model framework, the measured values of $v_{2}\\{4\\}$ and $v_{2}\\{2\\}$ are used ...

  4. The Research of the Baker Code Correlation Peak Extraction Method of Acousto-optic Correlator%声光相关器巴克码相关峰提取方法的研究

    Institute of Scientific and Technical Information of China (English)

    王素铭; 周鹰; 杨立峰; 王亚非; 高椿明; 王占平

    2012-01-01

    Acousto-optic signal processing is a sort of technology of spectrum analysis and correlation, taking a-cousto-optic device as the core, with the features of large instantaneous bandwidth, dynamic range, processing gain and high speed parallel capacity. According to the principle of incoherent time-integrating correlator, the methods of polynomial fitting and wavelet transform are used to resolve the problem of correlation peak extraction of baker code. At last, experimental results and comparison of two methods are also given.%声光信号处理技术是以声光器件为核心的频谱分析技术和相关处理技术,具有大瞬时带宽、大动态范围、高处理增益和高速并行能力.根据非相干时间积分声光相关器原理,针对巴克码相关峰提取问题,提出了多项式拟合和小波变换两种峰值提取方法,对两种方法进行了比较,并对实验结果进行了分析.

  5. A method for predicting DCT-based denoising efficiency for grayscale images corrupted by AWGN and additive spatially correlated noise

    Science.gov (United States)

    Rubel, Aleksey S.; Lukin, Vladimir V.; Egiazarian, Karen O.

    2015-03-01

    Results of denoising based on discrete cosine transform for a wide class of images corrupted by additive noise are obtained. Three types of noise are analyzed: additive white Gaussian noise and additive spatially correlated Gaussian noise with middle and high correlation levels. TID2013 image database and some additional images are taken as test images. Conventional DCT filter and BM3D are used as denoising techniques. Denoising efficiency is described by PSNR and PSNR-HVS-M metrics. Within hard-thresholding denoising mechanism, DCT-spectrum coefficient statistics are used to characterize images and, subsequently, denoising efficiency for them. Results of denoising efficiency are fitted for such statistics and efficient approximations are obtained. It is shown that the obtained approximations provide high accuracy of prediction of denoising efficiency.

  6. Synchronous two-dimensional MIR correlation spectroscopy (2D-COS) as a novel method for screening smoke tainted wine.

    Science.gov (United States)

    Fudge, Anthea L; Wilkinson, Kerry L; Ristic, Renata; Cozzolino, Daniel

    2013-08-15

    In this study, two-dimensional correlation spectroscopy (2D-COS) combined with mid-infrared (MIR) spectroscopy was evaluated as a novel technique for the identification of spectral regions associated with smoke-affected wine, for the purpose of screening taint arising from grapevine exposure to smoke. Smoke-affected wines obtained from experimental and industry sources were analysed using MIR spectroscopy and chemometrics, and calibration models developed. 2D-COS analysis was used to generate synchronous data maps for red and white cask wines spiked with guaiacol, a marker of smoke taint. Correlations were observed at wavelengths that could be attributable to aromatic C-C stretching, i.e., between 1400 and 1500 cm(-1), indicative of volatile phenols. These results demonstrate the potential of 2D-COS as a rapid, high-throughput technique for the preliminary screening of smoke tainted wine.

  7. A Review of Correlative Light and Electron Microscopy (CLEM) Methods, Markers, and Instrument Set Ups to Study Infectious Disease

    Science.gov (United States)

    2016-12-12

    with the oxidation reaction [43], and limited penetration [43, 72]. In fixed and non-fixed cells mitochondria generate reactive oxygen species (ROS... mitochondria during apoptosis. Nat Cell Biol, 2007. 9(9): p. 1057-65. 22. Kong, D. and J. Loncarek, Correlative light and electron microscopy analysis...there is need to study, at nanoscale, objects of interest which are commonly part of rare transient events or afflict a particular cell among a

  8. Identification of viscoplastic parameters and characterization of Lüders behaviour using digital image correlation and the virtual fields method

    OpenAIRE

    Avril, Stéphane; Pierron, Fabrice; Sutton, Michael A.; Yan, Junhui

    2008-01-01

    In this study, tensile loading experiments are performed on notched steel bars at an average applied strain rate of 1s-1. Displacement fields are measured across the specimen by coupling digital image correlation (DIC) with imaging using high speed CCD cameras (4796 fps). Results from the experiments indicate the presence of local strain rates ranging from 0.1 to 10s-1 in the notched specimens. The heterogeneity of the strain rate fields provides suitable conditions for determining simultaneo...

  9. The correlation between academic achievements, self-esteem and motivation of female seventh grade students: A mixed methods approach

    Science.gov (United States)

    Henman, Karen

    During the early grades, female students generally display enthusiasm for learning science. As these same students go though school, however, their level of motivation changes. Once female students reach high school, many lack the confidence to take chemistry and physics. Then, in college they lack the background necessary to major in chemistry, physics, and engineering. This study used quantitative data to investigate the correlation between female students' motivation, self-esteem, and standards-based state science achievement tests combined with a qualitative survey of student's perceptions of parents' attitudes toward science. The Children's Science Motivation Inventory (CAIMI) determined students' levels of motivation toward science. The Coopersmith Self-esteem Inventory (CSEI) ascertained female students' overall self-esteem. The ISTEP+ exam given in the 6th grade measured the students' academic achievement in science. Trained examiners who interviewed students comprised the qualitative component of the study. Each examiner elaborated on selected questions from the CSEI and CAIMI to determine the students' perceptions of parental attitudes toward science. A multiple regression was used to determine the correlation between self-esteem, motivation, and achievement in science. The correlation was strongest between motivation. Interviews revealed parents and teachers had the most influence on students' perception of science. In understanding the correlation between female students' motivation, achievement, and self-esteem, schools will gain further knowledge into how students relate to the academic field of science and can thus promote females' participation in more science courses in high school. This then will provide females the necessary background knowledge to pursue a greater number of science majors in college.

  10. Orbital-dependent second-order scaled-opposite-spin correlation functionals in the optimized effective potential method

    Science.gov (United States)

    Grabowski, Ireneusz; Fabiano, Eduardo; Teale, Andrew M.; Śmiga, Szymon; Buksztel, Adam; Della Sala, Fabio

    2014-07-01

    The performance of correlated optimized effective potential (OEP) functionals based on the spin-resolved second-order correlation energy is analysed. The relative importance of singly- and doubly- excited contributions as well as the effect of scaling the same- and opposite- spin components is investigated in detail comparing OEP results with Kohn-Sham (KS) quantities determined via an inversion procedure using accurate ab initio electronic densities. Special attention is dedicated in particular to the recently proposed scaled-opposite-spin OEP functional [I. Grabowski, E. Fabiano, and F. Della Sala, Phys. Rev. B 87, 075103 (2013)] which is the most advantageous from a computational point of view. We find that for high accuracy, a careful, system dependent, selection of the scaling coefficient is required. We analyse several size-extensive approaches for this selection. Finally, we find that a composite approach, named OEP2-SOSh, based on a post-SCF rescaling of the correlation energy can yield high accuracy for many properties, being comparable with the most accurate OEP procedures previously reported in the literature but at substantially reduced computational effort.

  11. Orbital-dependent second-order scaled-opposite-spin correlation functionals in the optimized effective potential method

    Energy Technology Data Exchange (ETDEWEB)

    Grabowski, Ireneusz, E-mail: ig@fizyka.umk.pl; Śmiga, Szymon; Buksztel, Adam [Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziadzka 5, 87-100 Torun (Poland); Fabiano, Eduardo [National Nanotechnology Laboratory, Istituto Nanoscienze–CNR, Via per Arnesano, I-73100 Lecce (Italy); Teale, Andrew M. [School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD (United Kingdom); Centre for Theoretical and Computational Chemistry, Department of Chemistry, University of Oslo, P.O. Box 1033 Blindern, N-0315 Oslo (Norway); Sala, Fabio Della [National Nanotechnology Laboratory, Istituto Nanoscienze–CNR, Via per Arnesano, I-73100 Lecce (Italy); Center for Biomolecular Nanotechnologies @UNILE, Istituto Italiano di Tecnologia (IIT), Via Barsanti, 73010 Arnesano (LE) (Italy)

    2014-07-14

    The performance of correlated optimized effective potential (OEP) functionals based on the spin-resolved second-order correlation energy is analysed. The relative importance of singly- and doubly- excited contributions as well as the effect of scaling the same- and opposite- spin components is investigated in detail comparing OEP results with Kohn–Sham (KS) quantities determined via an inversion procedure using accurate ab initio electronic densities. Special attention is dedicated in particular to the recently proposed scaled-opposite–spin OEP functional [I. Grabowski, E. Fabiano, and F. Della Sala, Phys. Rev. B 87, 075103 (2013)] which is the most advantageous from a computational point of view. We find that for high accuracy, a careful, system dependent, selection of the scaling coefficient is required. We analyse several size-extensive approaches for this selection. Finally, we find that a composite approach, named OEP2-SOSh, based on a post-SCF rescaling of the correlation energy can yield high accuracy for many properties, being comparable with the most accurate OEP procedures previously reported in the literature but at substantially reduced computational effort.

  12. Targeting c-Myc-activated genes with a correlation method: Detection of global changes in large gene expression network dynamics

    Science.gov (United States)

    Remondini, D.; O'Connell, B.; Intrator, N.; Sedivy, J. M.; Neretti, N.; Castellani, G. C.; Cooper, L. N.

    2005-01-01

    This work studies the dynamics of a gene expression time series network. The network, which is obtained from the correlation of gene expressions, exhibits global dynamic properties that emerge after a cell state perturbation. The main features of this network appear to be more robust when compared with those obtained with a network obtained from a linear Markov model. In particular, the network properties strongly depend on the exact time sequence relationships between genes and are destroyed by random temporal data shuffling. We discuss in detail the problem of finding targets of the c-myc protooncogene, which encodes a transcriptional regulator whose inappropriate expression has been correlated with a wide array of malignancies. The data used for network construction are a time series of gene expression, collected by microarray analysis of a rat fibroblast cell line expressing a conditional Myc-estrogen receptor oncoprotein. We show that the correlation-based model can establish a clear relationship between network structure and the cascade of c-myc-activated genes. PMID:15867157

  13. Fuzzy logic and optical correlation-based face recognition method for patient monitoring application in home video surveillance

    Science.gov (United States)

    Elbouz, Marwa; Alfalou, Ayman; Brosseau, Christian

    2011-06-01

    Home automation is being implemented into more and more domiciles of the elderly and disabled in order to maintain their independence and safety. For that purpose, we propose and validate a surveillance video system, which detects various posture-based events. One of the novel points of this system is to use adapted Vander-Lugt correlator (VLC) and joint-transfer correlator (JTC) techniques to make decisions on the identity of a patient and his three-dimensional (3-D) positions in order to overcome the problem of crowd environment. We propose a fuzzy logic technique to get decisions on the subject's behavior. Our system is focused on the goals of accuracy, convenience, and cost, which in addition does not require any devices attached to the subject. The system permits one to study and model subject responses to behavioral change intervention because several levels of alarm can be incorporated according different situations considered. Our algorithm performs a fast 3-D recovery of the subject's head position by locating eyes within the face image and involves a model-based prediction and optical correlation techniques to guide the tracking procedure. The object detection is based on (hue, saturation, value) color space. The system also involves an adapted fuzzy logic control algorithm to make a decision based on information given to the system. Furthermore, the principles described here are applicable to a very wide range of situations and robust enough to be implementable in ongoing experiments.

  14. Research and Correlation of Diagnostic Methods for Assessment of the State of Oil Filling in Cycloid Gearbox

    Directory of Open Access Journals (Sweden)

    Petr Baron

    2015-01-01

    Full Text Available The paper describes the research in the area of the application of diagnostic methods for assessment of the state of oil filling in cycloid gearbox of robotic manipulator. The experiments were realized on request of the manufacturer of the cycloid gearbox. Primarily, the two different methods were compared: an induction, magnetic method with the use of measurement system Cosmos-Steel Dust Checker and an RTG method, XRF (X-ray fluorescent method, analyses with use of X-ray radiation. These analytical methods provide the identification and quantification of emerging Fe abrasion particles occurring in the oil filling of the redactor. The results of the experiment pointed to the unsuitability of the application of the induction magnetic method for the assessment of an actual technical state of the cycloid gearbox. The reason for this lies in specific construction of the cycloid gearbox, with characteristic high operation temperatures of the oil filling, small dimensions, high transferred power, and gear ratio.

  15. Study of the dependence between the simultaneous wind speed and the global solar radiation measurements using the Time dependent Intrinsic Correlation method

    Science.gov (United States)

    Schmitt, F. G.; Calif, R.; Huang, Y.

    2014-12-01

    Wind and global solar radiation are complex atmospheric processes exhibiting nonstationary and nonlinear properties, involving with a high level intermittency degree on a broad range of spatial and temporal scales. It has been shown recently that the wind speed and the solar global radiation had intermittent and multiscaling statistics on mesoscales range.The emergence of electricity production units combining renewable wind and solar energy generation, need the understanding of the dependence between these two processes. The interest is to develop strategic tools in order to smooth the aggregate power output of this kind of electricity production unit.In this study, we study their multi-scale dynamics and we investigate possible correlations at different scales using a new methodology called Time Dependent Intrinsic Correlation (TDIC) based on the EMD (Emiprical Mode Decomposition) method. For that, the Time Dependent Intrinsic Correlation method is applied to simultaneous wind and global solar radiation measurements. The two time series are collected with a sampling time t=1h during five years at Guadeloupean Archipelago (French West Indies) located at 16°15'N latitude and 60°30'W longitude. After decomposition of both times series in fast and slow fluctuations with the EMD method, the Hilbert spectra are estimated for the both time series. The time evolution and the scale dependence of their correlation are determined at different time scales and for different intrinsic modes functions.

  16. Development of polaron-transformed explicitly correlated full configuration interaction method for investigation of quantum-confined Stark effect in GaAs quantum dots

    CERN Document Server

    Blanton, Christopher J; Chakraborty, Arindam

    2012-01-01

    The effect of external electric field on electron-hole correlation in GaAs quantum dots is investigated. The electron-hole Schrodinger equation in the presence of external electric field is solved using explicitly correlated full configuration interaction (XCFCI) method and accurate exciton binding energy and electron-hole recombination probability are obtained. The effect of the electric field was included in the 1-particle single component basis functions by performing variational polaron transformation. The quality of the wavefunction at small inter-particle distances was improved by using Gaussian-type geminal function that depended explicitly on the electron-hole separation distance. The parameters of the explicitly correlated function were determined variationally at each field strength. The scaling of total exciton energy, exciton binding energy, and electron-hole recombination probability with respect to the strength of the electric field was investigated. It was found that a 500 kV/cm change in elect...

  17. Pair correlation functions of two- and three-dimensional hard-core fluids confined into narrow pores: exact results from transfer-matrix method.

    Science.gov (United States)

    Gurin, Péter; Varga, Szabolcs

    2013-12-28

    The effect of confinement is studied on the local structure of two- and three-dimensional hard-core fluids. The hard disks are confined between two parallel lines, while the hard spheres are in a cylindrical hard pore. In both cases only nearest neighbour interactions are allowed between the particles. The vertical and longitudinal pair correlation functions are determined by means of the exact transfer-matrix method. The vertical pair correlation function indicates that the wall induced packing constraint gives rise to a zigzag (up-down sequence) shaped close packing structure in both two- and three-dimensional systems. The longitudinal pair correlation function shows that both systems transform continuously from a one-dimensional gas-like behaviour to a zigzag solid-like structure with increasing density.

  18. LDA + GTB (generalized tight-binding) method for the electronic structure calculations of strongly correlated electron systems: Application for the band structure calculations of p-type cuprates

    Energy Technology Data Exchange (ETDEWEB)

    Korshunov, Maxim M. [L.V. Kirensky Institute of Physics, Siberian Branch of RAS, Akademgorodok, 660036 Krasnoyarsk (Russian Federation); Max-Planck-Institut fuer Physik komplexer Systeme, Noethnitzer Str. 38, D-01187 Dresden (Germany)], E-mail: maxim@mpipks-dresden.mpg.de; Ovchinnikov, Sergey G. [Max-Planck-Institut fuer Physik komplexer Systeme, Noethnitzer Str. 38, D-01187 Dresden (Germany)

    2007-09-01

    Mean-field theory of the non-superconducting phase of the high-T{sub c} cuprates is formulated within the effective t-t'-t''-J model with three-site correlated hoppings. This model with the ab initio calculated parameters results from the LDA + GTB method. The static spin and kinematical correlation functions beyond Hubbard I approximation are calculated self-consistently taking into account hoppings to the first, the second, and the third neighboring sites, as well as the three-site correlated hoppings. The obtained Fermi surface evolves from hole-pockets at low-doping to large hole-type Fermi surface at higher doping concentrations. Calculated doping dependence of the nodal Fermi velocity, the effective mass and the chemical potential shift are in good agreement with experimental data.

  19. A method for an improved measurement of the electron-antineutrino correlation in free neutron beta decay

    Energy Technology Data Exchange (ETDEWEB)

    Wietfeldt, F.E. [Department of Physics, Tulane University, New Orleans, LA 70118 (United States)]. E-mail: few@tulane.edu; Fisher, B.M. [Department of Physics, Tulane University, New Orleans, LA 70118 (United States); Trull, C. [Department of Physics, Tulane University, New Orleans, LA 70118 (United States); Jones, G.L. [Physics Department, Hamilton College, Clinton, NY 13323 (United States); Collet, B. [Physics Department, Hamilton College, Clinton, NY 13323 (United States); Goldin, L. [Physics Department, Harvard University, Cambridge, MA 02139 (United States); Yerozolimsky, B.G. [Physics Department, Harvard University, Cambridge, MA 02139 (United States); Wilson, R. [Physics Department, Harvard University, Cambridge, MA 02139 (United States); Balashov, S. [Kurchatov Institute, Moscow (Russian Federation); Kurchatov Institute, Moscow (Russian Federation); Mostovoy, Yu. [Kurchatov Institute, Moscow (Russian Federation); Komives, A. [Physics Department, DePauw University, Greencastle, IN 46135 (United States); Leuschner, M. [Indiana University Cyclotron Facility, Bloomington, IN 47408 (United States); Byrne, J. [University of Sussex (United Kingdom); Bateman, F.B. [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States); Dewey, M.S. [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States); Nico, J.S. [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States); Thompson, A.K. [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States)

    2005-06-11

    The angular correlation between the beta electron and antineutrino in nuclear beta decay is characterized by the dimensionless parameter a. The value of a for free neutron decay, when combined with other neutron decay parameters, can be used to determine the weak vector and axial vector coupling constants g{sub V} and g{sub A} and test the validity and self-consistency of the Electroweak Standard Model. Previous experiments that measured a in neutron decay relied on precise proton spectroscopy and were limited by systematic effects at about the 5% level. We present a new approach to measuring a for which systematic uncertainties promise to be much smaller.

  20. Noise reduction methods applied to two-dimensional correlation spectroscopy (2D-COS) reveal complementary benefits of pre- and post-treatment.

    Science.gov (United States)

    Foist, Rod B; Schulze, H Georg; Ivanov, Andre; Turner, Robin F B

    2011-05-01

    Two-dimensional correlation spectroscopy (2D-COS) is a powerful spectral analysis technique widely used in many fields of spectroscopy because it can reveal spectral information in complex systems that is not readily evident in the original spectral data alone. However, noise may severely distort the information and thus limit the technique's usefulness. Consequently, noise reduction is often performed before implementing 2D-COS. In general, this is implemented using one-dimensional (1D) methods applied to the individual input spectra, but, because 2D-COS is based on sets of successive spectra and produces 2D outputs, there is also scope for the utilization of 2D noise-reduction methods. Furthermore, 2D noise reduction can be applied either to the original set of spectra before performing 2D-COS ("pretreatment") or on the 2D-COS output ("post-treatment"). Very little work has been done on post-treatment; hence, the relative advantages of these two approaches are unclear. In this work we compare the noise-reduction performance on 2D-COS of pretreatment and post-treatment using 1D (wavelets) and 2D algorithms (wavelets, matrix maximum entropy). The 2D methods generally outperformed the 1D method in pretreatment noise reduction. 2D post-treatment in some cases was superior to pretreatment and, unexpectedly, also provided correlation coefficient maps that were similar to 2D correlation spectroscopy maps but with apparent better contrast.

  1. Correlation functions of the integrable higher-spin XXX and XXZ spin chains through the fusion method

    Science.gov (United States)

    Deguchi, Tetsuo; Matsui, Chihiro

    2010-06-01

    For the integrable higher-spin XXX and XXZ spin chains we present multiple-integral representations for the correlation function of an arbitrary product of Hermitian elementary matrices in the massless ground state. We give a formula expressing it by a single term of multiple integrals. In particular, we explicitly derive the emptiness formation probability (EFP). We assume 2s-strings for the ground-state solution of the Bethe-ansatz equations for the spin-s XXZ chain, and solve the integral equations for the spin-s Gaudin matrix. In terms of the XXZ coupling Δ we define ζ by Δ=cos ζ, and put it in a region 0⩽ζ<π/2s of the gapless regime: -1<Δ⩽1 (0⩽ζ<π), where Δ=1 (ζ=0) corresponds to the antiferromagnetic point. We calculate the zero-temperature correlation functions by the algebraic Bethe-ansatz, introducing the Hermitian elementary matrices in the massless regime, and taking advantage of the fusion construction of the R-matrix of the higher-spin representations of the affine quantum group.

  2. Measurement of Spin Correlations in $t\\overline{t}$ Systems in the muon+jets Channel using a Matrix Element Method with the CMS Detector at the LHC.

    CERN Document Server

    AUTHOR|(SzGeCERN)683526; Ryckbosch, Dirk; Grünewald, Martin

    2015-01-01

    In this work, the consistency of the spin correlation strength in top quark pair events with the Standard Model (SM) prediction is tested in the muon+jets final state. The events are obtained from $\\mathrm{pp}$ collisions at a centre-of-mass energy of $\\sqrt{s}\\,=$ 8 TeV, corresponding to an integrated luminosity of 19.7 fb$^{-1}$. Using a Matrix Element Method, event likelihoods are calculated under two different top quark pair hypotheses: the SM hypothesis and a hypothesis which predicts zero spin correlation. Using the event likelihoods, a variable sensitive to the spin correlation strength is constructed. In a hypothesis testing procedure, the data are found to favour the SM hypothesis. Using a template fit method, the fraction of events that show SM spin correlations is measured to be $f\\,=\\,0.72\\,\\pm\\,0.08\\,\\mathrm{(stat)}{}^{+0.15}_{-0.13}\\,\\mathrm{(syst)}$, representing the most precise measurement of this quantity in the lepton+jets channel to date.

  3. Pregnancy termination in Matlab, Bangladesh: trends and correlates of use of safer and less-safe methods.

    Science.gov (United States)

    DaVanzo, Julie; Rahman, Mizanur

    2014-09-01

    Menstrual regulation (MR), a relatively safe form of pregnancy termination, is legal in Bangladesh during the early stages of pregnancy. However, little is known about the factors associated with whether women who terminate pregnancies choose this method or a less-safe one. Data from the Matlab Demographic Surveillance System on 122,691 pregnancies-5,221 (4.3%) of which were terminated-were used to examine trends between 1989 and 2008 in termination and in use of safer methods (MR or dilation and curettage) and less-safe (all other) methods of pregnancy termination. Logistic and multinomial logistic regressions were used to assess factors associated with whether women terminate pregnancies and whether they use safer methods. Sixty-seven percent of pregnancy terminations were by safer methods and 33% by less-safe means. The proportion of pregnancies that were terminated increased between 1989 and 2008; this increase was entirely due to increased use of safer methods. Women younger than 18 and those 25 or older were more likely than women aged 20-24 to terminate their pregnancies (odds ratios ranged from 1.5 among women aged 16-17 or 25-29 to 26.1 among those aged 45 or older). Among women who terminated their pregnancies, those aged 25-44 were more likely than those aged 20-24 to use a safer method. Compared with women who had no formal education, those with some education were more likely to terminate their pregnancies and to do so using safer methods. A growing proportion of pregnancies in Matlab are terminated, and these terminations are increasingly done using safer methods.

  4. A modified method for accurate correlation between the craze density and the optomechanical properties of fibers using Pluta microscope.

    Science.gov (United States)

    Sokkar, T Z N; El-Farahaty, K A; El-Bakary, M A; Omar, E Z; Hamza, A A

    2016-05-01

    A modified method was suggested to improve the performance of the Pluta microscope in its nonduplicated mode in the calculation of the areal craze density especially, for relatively low draw ratio (low areal craze density). This method decreases the error that is resulted from the similarity between the formed crazes and the dark fringes of the interference pattern. Furthermore, an accurate method to calculate the birefringence and the orientation function of the drawn fibers via nonduplicated Pluta polarizing interference microscope for high areal craze density (high draw ratio) was suggested. The advantage of the suggested method is to relate the optomechanical properties of the tested fiber with the areal craze density, for the same region of the fiber material.

  5. High-resolution optical refractometer based on a long-period grating Michelson interferometer using a cross-correlation signal-processing method

    Science.gov (United States)

    Zhou, Xinlei; Chen, Ke; Mao, Xuefeng; Peng, Wei; Yu, Qingxu

    2015-12-01

    We report a high-resolution optical refractometer based on the long-period grating Michelson interferometer. The interferometer phase shift depends on the refractive index that surrounds the fiber probe. A cross-correlation signal-processing method is used to demodulate the interferometer phase shift. Experimental results show that a resolution of 3×10-6 refractive index unit (RIU) can be obtained using this cross-correlation signal processing method. In addition, a measurement sensitivity up to 3×103 deg/RIU is showed as the surrounding refractive index changing from 1.33 to 1.42. Such high-resolution and low-cost optical refractometers would find more applications in chemical or biochemical sensing fields.

  6. Negative emotion differentiation: its personality and well-being correlates and a comparison of different assessment methods.

    Science.gov (United States)

    Erbas, Yasemin; Ceulemans, Eva; Lee Pe, Madeline; Koval, Peter; Kuppens, Peter

    2014-01-01

    Previous research has shown that individual differences in negative emotion differentiation may play a prominent role in well-being. Yet, many basic questions about negative emotion differentiation remain unanswered, including how it relates and overlaps with related and known dimensions of individual differences and what its possible underlying processes are. To answer these questions, in the current article we present three correlational studies that chart the nomological network of individual differences in negative emotion differentiation in terms of personality, difficulties in identifying and describing feelings, and several indicators of well-being, propose a novel paradigm to assess it in the lab, and explore relationships with a possible underlying mechanism in terms of the motivation to approach or avoid emotions. The results affirm consistent relations between negative emotion differentiation and indicators of adjustment like negative affect, self-esteem, neuroticism, depression and meta-knowledge about one's emotions, and show how it is related to the motivation to experience affective states.

  7. The neural correlates of happiness: A review of PET and fMRI studies using autobiographical recall methods.

    Science.gov (United States)

    Suardi, Angelo; Sotgiu, Igor; Costa, Tommaso; Cauda, Franco; Rusconi, Maria

    2016-06-01

    Although very difficult to define, happiness is becoming a core concept within contemporary psychology and affective neuroscience. In the last two decades, the increased use of neuroimaging techniques has facilitated empirical study of the neural correlates of happiness. This area of research utilizes procedures that induce positive emotion and mood, and autobiographical recall is one of the most widely used and effective approaches. In this article, we review eight positron emission tomography and seven functional magnetic resonance imaging studies that have investigated happiness by using autobiographical recall to induce emotion. Regardless of the neuroimaging technique used, the studies conducted so far have shown that remembering happy events is primarily associated with the activation of many areas, including anterior cingulate cortex, prefrontal cortex, and insula. Importantly, these areas are also found to be connected with other basic emotions, such as sadness and anger. In the conclusion, we integrate these findings, discussing important limitations of the extant literature and suggesting new research directions.

  8. Correlación entre diferentes métodos de evaluación de color en el clareamiento dental. Correlation between different methods for co

    OpenAIRE

    Grez, Patrício Vildosóla; Casielles, Javier Martin; Godoy,Eduardo Fernandez; Aguirre,pablo Angel; Reyes, Ivonne Ovalle; Andrade, Marcelo Ferrarezi de [UNESP; Cortés,Gustavo Moncada; Oliveira Júnior, Osmir Batista de [UNESP

    2014-01-01

    The aim of this study was to evaluate the correlation of color change on bleaching tooth through delta E (ΔE) by the spectrophotometer Spectroshade (SS) and digital program Scanwhite (SW). Methods: 25 patient volunteers were recruited from Operative Dentistry at Universidad de Chile Dental School, between 18 to 30 years, with good oral hygiene. Exclusion criteria: Previous experienced tooth bleaching, anterior restorations, cervical lesions, pain dental, pregnant patient, stained teeth, malpo...

  9. A comparative study of the centroid and ring-polymer molecular dynamics methods for approximating quantum time correlation functions from path integrals

    Science.gov (United States)

    Pérez, Alejandro; Tuckerman, Mark E.; Müser, Martin H.

    2009-05-01

    The problems of ergodicity and internal consistency in the centroid and ring-polymer molecular dynamics methods are addressed in the context of a comparative study of the two methods. Enhanced sampling in ring-polymer molecular dynamics (RPMD) is achieved by first performing an equilibrium path integral calculation and then launching RPMD trajectories from selected, stochastically independent equilibrium configurations. It is shown that this approach converges more rapidly than periodic resampling of velocities from a single long RPMD run. Dynamical quantities obtained from RPMD and centroid molecular dynamics (CMD) are compared to exact results for a variety of model systems. Fully converged results for correlations functions are presented for several one dimensional systems and para-hydrogen near its triple point using an improved sampling technique. Our results indicate that CMD shows very similar performance to RPMD. The quality of each method is further assessed via a new χ2 descriptor constructed by transforming approximate real-time correlation functions from CMD and RPMD trajectories to imaginary time and comparing these to numerically exact imaginary time correlation functions. For para-hydrogen near its triple point, it is found that adiabatic CMD and RPMD both have similar χ2 error.

  10. Paramagnetic susceptibility and correlation functions of a d-dimensional classical Heisenberg ferromagnet via the two-time Green function method

    Science.gov (United States)

    Campana, L. S.; Cavallo, A.; Cesare, L. De; Esposito, U.; Naddeo, A.

    2017-04-01

    In the present paper we investigate the paramagnetic susceptibility and the short-range order correlation functions of a d-dimensional classical isotropic ferromagnetic Heisenberg model with short-range exchange interactions by employing the two-time Green function method in classical statistical mechanics. Here we use Tyablikov-Callen-like decouplings for higher order Green functions and a formula for magnetization recently obtained by extension of the well known Callen method developed many years ago for the quantum isotropic Heisenberg model. Although our analysis is true for any temperature and dimensionality, we focus on one-, and some two- and three-dimensional lattices of experimental interest and derive asymptotic expressions for susceptibility and correlation functions within the paramagnetic phase close to the phase boundary and in the high-temperature regime. Besides, we present a Fourier series expansion method for deriving the high-temperature behaviors of the correlation functions. Our predictions, as obtained from a genuine classical many-body framework, may constitute a good reference point for the quantum counterparts emerging in the classical limit at the same level of approximation. Of course, although the classical spin models have unrealistic properties at sufficiently low temperatures, our classical analysis provides, in a relatively simple way as compared to a quantum treatment, an experimentally interesting scenario at finite temperature and dimensionalities d ≥ 1.

  11. Computational methods using genome-wide association studies to predict radiotherapy complications and to identify correlative molecular processes

    Science.gov (United States)

    Oh, Jung Hun; Kerns, Sarah; Ostrer, Harry; Powell, Simon N.; Rosenstein, Barry; Deasy, Joseph O.

    2017-02-01

    The biological cause of clinically observed variability of normal tissue damage following radiotherapy is poorly understood. We hypothesized that machine/statistical learning methods using single nucleotide polymorphism (SNP)-based genome-wide association studies (GWAS) would identify groups of patients of differing complication risk, and furthermore could be used to identify key biological sources of variability. We developed a novel learning algorithm, called pre-conditioned random forest regression (PRFR), to construct polygenic risk models using hundreds of SNPs, thereby capturing genomic features that confer small differential risk. Predictive models were trained and validated on a cohort of 368 prostate cancer patients for two post-radiotherapy clinical endpoints: late rectal bleeding and erectile dysfunction. The proposed method results in better predictive performance compared with existing computational methods. Gene ontology enrichment analysis and protein-protein interaction network analysis are used to identify key biological processes and proteins that were plausible based on other published studies. In conclusion, we confirm that novel machine learning methods can produce large predictive models (hundreds of SNPs), yielding clinically useful risk stratification models, as well as identifying important underlying biological processes in the radiation damage and tissue repair process. The methods are generally applicable to GWAS data and are not specific to radiotherapy endpoints.

  12. Measurement of multi-particle azimuthal correlations with the subevent method in $pp$ and $p$+Pb collisions with the ATLAS detector

    CERN Document Server

    Behera, Arabinda; The ATLAS collaboration

    2017-01-01

    The measurement of four-particle cumulant elliptic flow coefficients $c_2\\{4\\}$ and $v_2\\{4\\}$ are presented using 0.17 $pb^{-1}$ p+p data at $\\sqrt{s_{NN}}$ = 5.02 TeV, 0.9 $pb^{-1}$ p+p data at $\\sqrt{s_{NN}}$ = 13 TeV and 28 $nb^{-1}$ p+Pb data $\\sqrt{s_{NN}}$ = 5.02 TeV. The $c_2\\{4\\}$ are calculated as a function of average number of charged particles, $\\langle N_{\\text{ch}}\\rangle$, using standard cumulant method, as well as the recently proposed two-subevent and three-subevent cumulant methods. The three-subevent method is found to be much less sensitive to the short range correlations originating mostly from jets and di-jets compared to the other two methods, which can lead to the observation of negative $c_2\\{4\\}$ and a real $v_2\\{4\\} = -\\left( c_2\\{4\\}\\right)^{1/4}$ in all collision systems. The magnitude of $c_2\\{4\\}$ is nearly independent of $\\langle N_{\\text{ch}}\\rangle$. The $v_2\\{4\\}$ is found to be smaller than the $v_2\\{2\\}$ measured from two-particle correlation method, as expected for long-...

  13. Immunohistochemical assessment of oestrogen and progesterone receptors: correlations with the DCC method and clinical outcome in primary breast cancer patients

    DEFF Research Database (Denmark)

    Grabau, D A; Thorpe, S M; Knoop, A

    2000-01-01

    of patients, receptor positive cases fared better than negative cases in all situations. Investigation of the prognostic power revealed that classification based on IHA allowed better discrimination of patients than classification based on the DCC method. The reason for this difference might be because...... distinction between benign and malignant tissue is possible using the IHAmethod. Thus, IHAresults appear to be more clinically relevant....

  14. MBA Students' Quality Improvement: The Correlation Analysis of Students' Personal Traits and Attitudes towards Teaching Methods at a Chinese University

    Science.gov (United States)

    Kong, Rui; Gao, Xiaowei; Zhong, Wanxing; Zhou, Xiaoling

    2015-01-01

    MBA education has become the fastest growing segment of education in China in recent years and a segment that can now be considered indispensable. However, how best to teach it has long been a source of debate. One of the key issues is how to match student traits with teaching methods. While engaged as teachers of marketing management, the authors…

  15. MBA Students' Quality Improvement: The Correlation Analysis of Students' Personal Traits and Attitudes towards Teaching Methods at a Chinese University

    Science.gov (United States)

    Kong, Rui; Gao, Xiaowei; Zhong, Wanxing; Zhou, Xiaoling

    2015-01-01

    MBA education has become the fastest growing segment of education in China in recent years and a segment that can now be considered indispensable. However, how best to teach it has long been a source of debate. One of the key issues is how to match student traits with teaching methods. While engaged as teachers of marketing management, the authors…

  16. Unreported seismic events found far off-shore Mexico using full-waveform, cross-correlation detection method.

    Science.gov (United States)

    Solano, ErickaAlinne; Hjorleifsdottir, Vala; Perez-Campos, Xyoli

    2015-04-01

    A large subset of seismic events do not have impulsive arrivals, such as low frequency events in volcanoes, earthquakes in the shallow part of the subduction interface and further down dip from the traditional seismogenic part, glacial events, volcanic and non-volcanic tremors and landslides. A suite of methods can be used to detect these non-impulsive events. One of this methods is the full-waveform detection based on time reversal methods (Solano, et al , submitted to GJI). The method uses continuous observed seismograms, together with Greens functions and moment tensor responses calculated for an arbitrary 3D structure. This method was applied to the 2012 Ometepec-Pinotepa Nacional earthquake sequence in Guerrero, Mexico. During the span time of the study, we encountered three previously unknown events. One of this events was an impulsive earthquake in the Ometepec area, that only has clear arrivals on three stations and was therefore not located and reported by the SSN. The other two events are previously undetected events, very depleted in high frequencies, that occurred far outside the search area. A very rough estimate gives the location of this two events in the portion of the East Pacific Rise around 9 N. These two events are detected despite their distance from the search area, due to favorable move-out on the array of the Mexican National Seismological Service network (SSN). We are expanding the study area to the EPR and to a larger period of time, with the objective of finding more events in that region. We will present an analysis of the newly detected events, as well as any further findings at the meeting.

  17. Efficient and accurate local single reference correlation methods for high-spin open-shell molecules using pair natural orbitals

    Science.gov (United States)

    Hansen, Andreas; Liakos, Dimitrios G.; Neese, Frank

    2011-12-01

    A production level implementation of the high-spin open-shell (spin unrestricted) single reference coupled pair, quadratic configuration interaction and coupled cluster methods with up to doubly excited determinants in the framework of the local pair natural orbital (LPNO) concept is reported. This work is an extension of the closed-shell LPNO methods developed earlier [F. Neese, F. Wennmohs, and A. Hansen, J. Chem. Phys. 130, 114108 (2009), 10.1063/1.3086717; F. Neese, A. Hansen, and D. G. Liakos, J. Chem. Phys. 131, 064103 (2009), 10.1063/1.3173827]. The internal space is spanned by localized orbitals, while the external space for each electron pair is represented by a truncated PNO expansion. The laborious integral transformation associated with the large number of PNOs becomes feasible through the extensive use of density fitting (resolution of the identity (RI)) techniques. Technical complications arising for the open-shell case and the use of quasi-restricted orbitals for the construction of the reference determinant are discussed in detail. As in the closed-shell case, only three cutoff parameters control the average number of PNOs per electron pair, the size of the significant pair list, and the number of contributing auxiliary basis functions per PNO. The chosen threshold default values ensure robustness and the results of the parent canonical methods are reproduced to high accuracy. Comprehensive numerical tests on absolute and relative energies as well as timings consistently show that the outstanding performance of the LPNO methods carries over to the open-shell case with minor modifications. Finally, hyperfine couplings calculated with the variational LPNO-CEPA/1 method, for which a well-defined expectation value type density exists, indicate the great potential of the LPNO approach for the efficient calculation of molecular properties.

  18. A novel 2nd-order shape function based digital image correlation method for large deformation measurements

    Science.gov (United States)

    Bai, Ruixiang; Jiang, Hao; Lei, Zhenkun; Li, Weikang

    2017-03-01

    Compared with the traditional forward compositional matching strategy, the inverse compositional matching strategy has almost the same accuracy, but has an obviously higher efficiency than the former in digital image correlation (DIC) algorithms. Based on the inverse compositional matching strategy and the auxiliary displacement functions, a more accurate inverse compositional Gauss-Newton (IC-GN2) algorithm with a new second-order shape operator is proposed for nonuniform and large deformation measurements. A theoretical deduction showed that the new proposed second-order shape operator is invertible and can steadily attain second-order precision. The result of the numerical simulation showed that the matching accuracy of the new IC-GN2 algorithm is the same as that of the forward compositional Gauss-Newton (FC-GN2) algorithm and is relatively better than in IC-GN2 algorithm. Finally, a rubber tension experiment with a large deformation of 27% was performed to validate the feasibility of the proposed algorithm.

  19. Global study of beyond-mean-field correlation energies in covariant energy density functional theory using a collective Hamiltonian method

    CERN Document Server

    Lu, K Q; Li, Z P; Yao, J M; Meng, J

    2015-01-01

    We report the first global study of dynamic correlation energies (DCEs) associated with rotational motion and quadrupole shape vibrational motion in a covariant energy density functional (CEDF) for 575 even-even nuclei with proton numbers ranging from $Z=8$ to $Z=108$ by solving a five-dimensional collective Hamiltonian, the collective parameters of which are determined from triaxial relativistic mean-field plus BCS calculation using the PC-PK1 force. After taking into account these beyond mean-field DCEs, the root-mean-square (rms) deviation with respect to nuclear masses is reduced significantly down to 1.14 MeV, which is smaller than those of other successful CEDFs: NL3* (2.96 MeV), DD-ME2 (2.39 MeV), DD-ME$\\delta$ (2.29 MeV) and DD-PC1 (2.01 MeV). Moreover, the rms deviation for two-nucleon separation energies is reduced by $\\sim34\\%$ in comparison with cranking prescription.

  20. A correlational method to concurrently measure envelope and temporal fine structure weights: effects of age, cochlear pathology, and spectral shaping.

    Science.gov (United States)

    Fogerty, Daniel; Humes, Larry E

    2012-09-01

    The speech signal may be divided into spectral frequency-bands, each band containing temporal properties of the envelope and fine structure. This study measured the perceptual weights for the envelope and fine structure in each of three frequency bands for sentence materials in young normal-hearing listeners, older normal-hearing listeners, aided older hearing-impaired listeners, and spectrally matched young normal-hearing listeners. The availability of each acoustic property was independently varied through noisy signal extraction. Thus, the full speech stimulus was presented with noise used to mask six different auditory channels. Perceptual weights were determined by correlating a listener's performance with the signal-to-noise ratio of each acoustic property on a trial-by-trial basis. Results demonstrate that temporal fine structure perceptual weights remain stable across the four listener groups. However, a different weighting typography was observed across the listener groups for envelope cues. Results suggest that spectral shaping used to preserve the audibility of the speech stimulus may alter the allocation of perceptual resources. The relative perceptual weighting of envelope cues may also change with age. Concurrent testing of sentences repeated once on a previous day demonstrated that weighting strategies for all listener groups can change, suggesting an initial stabilization period or susceptibility to auditory training.

  1. Communication: Almost error-free resolution-of-the-identity correlation methods by null space removal of the particle-hole interactions

    Science.gov (United States)

    Schurkus, Henry F.; Luenser, Arne; Ochsenfeld, Christian

    2017-06-01

    We present a method to improve upon the resolution-of-the-identity (RI) for correlation methods. While RI is known to allow for drastic speedups, it relies on a cancellation of errors. Our method eliminates the errors introduced by RI which are known to be problematic for absolute energies. In this way, independence of the error compensation assumption for relative energies is also achieved. The proposed method is based on the idea of starting with an oversized RI basis and projecting out all of its unphysical parts. The approach can be easily implemented into existing RI codes and results in an overhead of about 30%, while effectively removing the RI error. In passing, this process alleviates the problem that for many frequently employed basis sets no optimized RI basis sets have been constructed. In this paper, the theory is presented and results are discussed exemplarily for the random phase approximation and Møller-Plesset perturbation theory.

  2. Review on Mining Methods of Correlated Bursty Topic Patterns%关联爆发主题模式挖掘方法研究综述

    Institute of Scientific and Technical Information of China (English)

    黄永文

    2012-01-01

    简要介绍关联爆发主题模式的含义,从探测与发现爆发主题、定位爆发主题的爆发时间段以及分析和挖掘出关联的爆发主题三个方面出发,研究关联爆发主题模式挖掘的关键问题。最后,对基于文档集、基于同步文本流、以及基于异步文本流的关联爆发主题挖掘的相关研究进展进行分析。%This paper introduces the definition of correlated bursty topic patterns and studies the key issues of mining correlated bursty topic patterns such as detect bursty topics, locate bursty period of a bursty topic and discover correlated bursty topics. Finally, it analyzes the methods of mining correlated bursty topics from text collections, synchronous text streams and asynchronous text streams.

  3. Real-Time and Robust Method for Hand Gesture Recognition System Based on Cross-Correlation Coefficient

    OpenAIRE

    Azad, Reza; Azad, Babak; Kazerooni, Iman Tavakoli

    2014-01-01

    Hand gesture recognition possesses extensive applications in virtual reality, sign language recognition, and computer games. The direct interface of hand gestures provides us a new way for communicating with the virtual environment. In this paper a novel and real-time approach for hand gesture recognition system is presented. In the suggested method, first, the hand gesture is extracted from the main image by the image segmentation and morphological operation and then is sent to feature extra...

  4. Real-Time and Robust Method for Hand Gesture Recognition System Based on Cross-Correlation Coefficient

    OpenAIRE

    Reza Azad; Babak Azad; Iman tavakoli kazerooni

    2013-01-01

    Hand gesture recognition possesses extensive applications in virtual reality, sign language recognition, and computer games. The direct interface of hand gestures provides us a new way for communicating with the virtual environment. In this paper a novel and real-time approach for hand gesture recognition system is presented. In the suggested method, first, the hand gesture is extracted from the main image by the image segmentation and morphological operation and then is sent to feature extra...

  5. Ab initio-driven nuclear energy density functional method. A proposal for safe/correlated/improvable parametrizations of the off-diagonal EDF kernels

    CERN Document Server

    Duguet, T; Ebran, J -P; Lesinski, T; Somà, V

    2015-01-01

    This programmatic paper lays down the possibility to reconcile the necessity to resum many-body correlations into the energy kernel with the fact that safe multi-reference energy density functional (EDF) calculations cannot be achieved whenever the Pauli principle is not strictly enforced, as is for example the case when many-body correlations are parametrized under the form of empirical density dependencies. Our proposal is to exploit a newly developed ab initio many-body formalism to guide the construction of safe, explicitly correlated and systematically improvable parametrizations of the {\\it off-diagonal} energy and norm kernels that lie at the heart of the nuclear EDF method. The many-body formalism of interest relies on the concepts of symmetry breaking {\\it and} restoration that have made the fortune of the nuclear EDF method and is, as such, amenable to this guidance. After elaborating on our proposal, we briefly outline the project we plan to execute in the years to come.

  6. Collaborative study for the validation of serological methods for potency testing of diphtheria toxoid vaccines - extended study: correlation of serology with in vivo toxin neutralisation.

    Science.gov (United States)

    Sesardic, D; Winsnes, R; Rigsby, P; Behr-Gross, M-E

    2004-01-01

    Phase I of BSP034 collaborative study was extended in two laboratories to include correlation of serology with in vivo toxin neutralisation test (TNT) using 2 separate sets of 20 serum pools, produced in-house. The study investigated the extent to which the in vitro methods for diphtheria antibodies, Vero cell assay and diphtheria enzyme-linked immunosorbent assay for diphtheria antitoxin (D-ELISA), can detect neutralising antibodies by comparison with TNT in guinea pigs. The study was also performed to compare the antibody neutralising potency obtained in relation to guinea pig (GP) or equine (DI) antitoxin standard. In addition, the study provided an opportunity to compare ELISA for tetanus antitoxin (T-ELISA) and TNT assay for detection of anti-tetanus antibodies, from the same set of serum pools. The data obtained show that antitoxin potency obtained by Vero cell assay, D-ELISA and T-ELISA using the same GP standard, highly correlated with neutralising potency as determined in respective TNT assays. Vero cell assay with DI provided estimates that also correlated with neutralising potency, but were of significantly lower titre. Since reference to DI standard is widely used in serodiagnosis, as well as in clinical studies where diphtheria antitoxin titres obtained in the Vero cell method are taken as surrogate markers for vaccine efficacy, it should be investigated if a similar difference is also observed for human serology.

  7. LDA+{sigma}({omega}) method for the electronic structure of strongly correlated antiferromagnetic materials: application to La{sub 2}CuO{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Navarro, A.; Costa-Quintana, J.; Lopez-Aguilar, F. [Groupe d' Electromagnetisme, Departament de Fisica, Edifici Cn, Facultat de Ciencies, Universitat Autonoma de Barcelona, 08193 Bellaterra (Barcelona) (Spain)

    2002-09-08

    In this paper we present a method for obtaining the quasiband structure and the renormalized density of quasistates of strongly correlated systems with antiferromagnetic ordering. We calculate the electronic structure of La{sub 2}CuO{sub 4} in order to test this method. The first step required is to calculate the electronic structure from the local density approximation (LDA) in order to obtain the initial non-interacting ground state. The LDA density of states in strongly correlated systems usually presents serious discrepancies with experimental results. As is well known, these discrepancies, fundamentally concerning photoemission, are due to the fact that the dynamic correlation effects are not taken into account within the LDA. In order to include these effects, we obtain a self-energy potential which allows the initial LDA electronic structure to connect with that of the antiferromagnetic ground state arising from a Bogolyubov-like transformation. Within this new ground state, we determine an antiferromagnetic self-energy by means of a spin density wave procedure, and the interacting Green function yields a density of states which is in reasonable agreement with the experimental photoemission result. (Abstract Copyright [2002], Wiley Periodicals, Inc.)

  8. Correlation of In Vivo and In Vitro Methods in Measuring Choroidal Vascularization Volumes Using a Subretinal Injection Induced Choroidal Neovascularization Model

    Institute of Scientific and Technical Information of China (English)

    Chuang Nie; Mao-Nian Zhang; Hong-Wei Zhao; Thomas D Olsen; Kyle Jackman; Lian-Na Hu; Wen-Ping Ma

    2015-01-01

    Background:In vivo quantification of choroidal neovascularization (CNV) based on noninvasive optical coherence tomography (OCT) examination and in vitro choroidal flatmount immunohistochemistry stained of CNV currently were used to evaluate the process and severity of age-related macular degeneration (AMD) both in human and animal studies.This study aimed to investigate the correlation between these two methods in murine CNV models induced by subretinal injection.Methods:CNV was developed in 20 C57BL6/j mice by subretinal injection of adeno-associated viral delivery of a short hairpin RNA targeting sFLT-1 (AAV.shRNA.sFLT-1),as reported previously.After 4 weeks,CNV was imaged by OCT and fluorescence angiography.The scaling factors for each dimension,x,y,and z (μm/pixel) were recorded,and the corneal curvature standard was adjusted from human (7.7) to mice (1.4).The volume of each OCT image stack was calculated and then normalized by multiplying the number of voxels by the scaling factors for each dimension in Seg3D software (University of Utah Scientific Computing and Imaging Institute,available at http://www.sci.utah.edu/cibc-software/seg3d.html).Eighteen mice were prepared for choroidal flatmounts and stained by CD31.The CNV volumes were calculated using scanning laser confocal microscopy after immunohistochemistry staining.Two mice were stained by Hematoxylin and Eosin for observing the CNV morphology.Results:The CNV volume calculated using OCT was,on average,2.6 times larger than the volume calculated using the laser confocal microscopy.The correlation statistical analysis showed OCT measuring of CNV correlated significantly with the in vitro method (R2 =0.448,P=0.001,n =18).The correlation coefficient for CNV quantification using OCT and confocal microscopy was 0.693 (n =18,P =0.001).Conclusions:There is a fair linear correlation on CNV volumes between in vivo and in vitro methods in CNV models induced by subretinal injection.The result might provide a useful

  9. Correlation of In Vivo and In Vitro Methods in Measuring Choroidal Vascularization Volumes Using a Subretinal Injection Induced Choroidal Neovascularization Model

    Directory of Open Access Journals (Sweden)

    Chuang Nie

    2015-01-01

    Full Text Available Background: In vivo quantification of choroidal neovascularization (CNV based on noninvasive optical coherence tomography (OCT examination and in vitro choroidal flatmount immunohistochemistry stained of CNV currently were used to evaluate the process and severity of age-related macular degeneration (AMD both in human and animal studies. This study aimed to investigate the correlation between these two methods in murine CNV models induced by subretinal injection. Methods: CNV was developed in 20 C57BL6/j mice by subretinal injection of adeno-associated viral delivery of a short hairpin RNA targeting sFLT-1 (AAV.shRNA.sFLT-1, as reported previously. After 4 weeks, CNV was imaged by OCT and fluorescence angiography. The scaling factors for each dimension, x, y, and z (μm/pixel were recorded, and the corneal curvature standard was adjusted from human (7.7 to mice (1.4. The volume of each OCT image stack was calculated and then normalized by multiplying the number of voxels by the scaling factors for each dimension in Seg3D software (University of Utah Scientific Computing and Imaging Institute, available at http://www.sci.utah.edu/cibc-software/seg3d.html. Eighteen mice were prepared for choroidal flatmounts and stained by CD31. The CNV volumes were calculated using scanning laser confocal microscopy after immunohistochemistry staining. Two mice were stained by Hematoxylin and Eosin for observing the CNV morphology. Results: The CNV volume calculated using OCT was, on average, 2.6 times larger than the volume calculated using the laser confocal microscopy. The correlation statistical analysis showed OCT measuring of CNV correlated significantly with the in vitro method (R 2 =0.448, P = 0.001, n = 18. The correlation coefficient for CNV quantification using OCT and confocal microscopy was 0.693 (n = 18, P = 0.001. Conclusions: There is a fair linear correlation on CNV volumes between in vivo and in vitro methods in CNV models induced by subretinal

  10. Direct digital method fast-acting analysis of the correlation-interferometric radio direction-finding with reconstructing of spatial analytical

    Directory of Open Access Journals (Sweden)

    V. V. Tsyporenko

    2013-04-01

    Full Text Available Introduction. Nowadays radio control of radio electronic devices must be carried out in the conditions of sticky electromagnetic wicket, large prior uncertainty in relation to the parameters of radiations, and also in the conditions of the real time realization. The use and researches of direct digital methods of correlation-interferometric direction-finding is perspective direction in radio control realization for the indicated terms. Fundamentals of researches. In this paper, the direct digital method fast-acting analysis of the correlation-interferometric radio direction-finding with reconstructing of spatial analytical signal is executed. The estimation of time charges, fast-acting and relative time efficiency of method is executed. Conclusions. It is certain that analyzed direct method of direction-finding provides a spatial selection and simultaneous direction-finding of radiations which get in the pass frequencies band of simultaneous analysis with a width to one hundred ten megahertz real-time with the use of only one signal processor.

  11. Estimation of Flow Duration Curve for Ungauged Catchments using Adaptive Neuro-Fuzzy Inference System and Map Correlation Method: A Case Study from Turkey

    Science.gov (United States)

    Kentel, E.; Dogulu, N.

    2015-12-01

    In Turkey the experience and data required for a hydrological model setup is limited and very often not available. Moreover there are many ungauged catchments where there are also many planned projects aimed at utilization of water resources including development of existing hydropower potential. This situation makes runoff prediction at locations with lack of data and ungauged locations where small hydropower plants, reservoirs, etc. are planned an increasingly significant challenge and concern in the country. Flow duration curves have many practical applications in hydrology and integrated water resources management. Estimation of flood duration curve (FDC) at ungauged locations is essential, particularly for hydropower feasibility studies and selection of the installed capacities. In this study, we test and compare the performances of two methods for estimating FDCs in the Western Black Sea catchment, Turkey: (i) FDC based on Map Correlation Method (MCM) flow estimates. MCM is a recently proposed method (Archfield and Vogel, 2010) which uses geospatial information to estimate flow. Flow measurements of stream gauging stations nearby the ungauged location are the only data requirement for this method. This fact makes MCM very attractive for flow estimation in Turkey, (ii) Adaptive Neuro-Fuzzy Inference System (ANFIS) is a data-driven method which is used to relate FDC to a number of variables representing catchment and climate characteristics. However, it`s ease of implementation makes it very useful for practical purposes. Both methods use easily collectable data and are computationally efficient. Comparison of the results is realized based on two different measures: the root mean squared error (RMSE) and the Nash-Sutcliffe Efficiency (NSE) value. Ref: Archfield, S. A., and R. M. Vogel (2010), Map correlation method: Selection of a reference streamgage to estimate daily streamflow at ungaged catchments, Water Resour. Res., 46, W10513, doi:10.1029/2009WR008481.

  12. 基于相关性分析的硬件木马检测方法%Hardware Trojan Detection Method Based on Correlation Analysis

    Institute of Scientific and Technical Information of China (English)

    刘长龙; 赵毅强; 史亚峰; 冯紫竹

    2013-01-01

    为提高硬件木马检测的准确率,提出一种基于相关性分析的检测方法。在完成木马功耗建模的基础上,提出并分析利用经典相关系数进行木马检测的可行性以及存在的缺点,根据木马检测的特点,优化检测系数,给出利用区间重叠比作为木马判定依据的检测方法。实验结果表明,与采用经典相关系数的方法相比,该方法在降低约6%检测准确率的前提下,能使鲁棒性提高1倍以上。%To improve the accuracy of the hardware trojan detection, a method based on the correlation analysis is presented. After a power modeling of the trojan, the feasibility and defect of the detection method by using the classical correlation coefficient are analyzed, the detection coefficient is optimized according to the characteristics of trojan detection, and the detection method depended on the region overlap ratio is presented. Experimental results show that this method can provide more than two times of robustness when the detection accuracy declined about 6%compared with the classical correlation coefficient.

  13. SparseMaps—A systematic infrastructure for reduced-scaling electronic structure methods. IV. Linear-scaling second-order explicitly correlated energy with pair natural orbitals

    Science.gov (United States)

    Pavošević, Fabijan; Pinski, Peter; Riplinger, Christoph; Neese, Frank; Valeev, Edward F.

    2016-04-01

    We present a formulation of the explicitly correlated second-order Møller-Plesset (MP2-F12) energy in which all nontrivial post-mean-field steps are formulated with linear computational complexity in system size. The two key ideas are the use of pair-natural orbitals for compact representation of wave function amplitudes and the use of domain approximation to impose the block sparsity. This development utilizes the concepts for sparse representation of tensors described in the context of the domain based local pair-natural orbital-MP2 (DLPNO-MP2) method by us recently [Pinski et al., J. Chem. Phys. 143, 034108 (2015)]. Novel developments reported here include the use of domains not only for the projected atomic orbitals, but also for the complementary auxiliary basis set (CABS) used to approximate the three- and four-electron integrals of the F12 theory, and a simplification of the standard B intermediate of the F12 theory that avoids computation of four-index two-electron integrals that involve two CABS indices. For quasi-1-dimensional systems (n-alkanes), the O (" separators="N ) DLPNO-MP2-F12 method becomes less expensive than the conventional O (" separators="N5 ) MP2-F12 for n between 10 and 15, for double- and triple-zeta basis sets; for the largest alkane, C200H402, in def2-TZVP basis, the observed computational complexity is N˜1.6, largely due to the cubic cost of computing the mean-field operators. The method reproduces the canonical MP2-F12 energy with high precision: 99.9% of the canonical correlation energy is recovered with the default truncation parameters. Although its cost is significantly higher than that of DLPNO-MP2 method, the cost increase is compensated by the great reduction of the basis set error due to explicit correlation.

  14. Predictive analysis of beer quality by correlating sensory evaluation with higher alcohol and ester production using multivariate statistics methods.

    Science.gov (United States)

    Dong, Jian-Jun; Li, Qing-Liang; Yin, Hua; Zhong, Cheng; Hao, Jun-Guang; Yang, Pan-Fei; Tian, Yu-Hong; Jia, Shi-Ru

    2014-10-15

    Sensory evaluation is regarded as a necessary procedure to ensure a reproducible quality of beer. Meanwhile, high-throughput analytical methods provide a powerful tool to analyse various flavour compounds, such as higher alcohol and ester. In this study, the relationship between flavour compounds and sensory evaluation was established by non-linear models such as partial least squares (PLS), genetic algorithm back-propagation neural network (GA-BP), support vector machine (SVM). It was shown that SVM with a Radial Basis Function (RBF) had a better performance of prediction accuracy for both calibration set (94.3%) and validation set (96.2%) than other models. Relatively lower prediction abilities were observed for GA-BP (52.1%) and PLS (31.7%). In addition, the kernel function of SVM played an essential role of model training when the prediction accuracy of SVM with polynomial kernel function was 32.9%. As a powerful multivariate statistics method, SVM holds great potential to assess beer quality.

  15. Pearson相关系数法快慢横波波场分离%Wave filed separation of fast-slow shear waves by Pearson correlation coefficient method

    Institute of Scientific and Technical Information of China (English)

    王凯; 冯晅; 刘财

    2012-01-01

    横波分裂是各向异性介质的重要特征,当横波或转换波穿过各向异性介质到达地面时,地面三分量检波器的x分量和y分量接收到的地震记录中都会同时存在快横波和慢横波.将快横波和慢横波进行分离,进而计算介质的各向异性参数是多分量数据处理中重要的一步.将数学中的Pearson相关系数引入到多分量地震勘探中,提出了Pearson相关系数法进行旋转角度识别,进而分离快、慢横波波场.相比于传统的互相关法,Pearson相关系数法从精度、抗噪性能和计算效率上都有提高.%Shear-wave splitting is an important characteristic of anisotropic media. Generally, when S or P-SV waves reach to the ground through anisotropic media, the seismic record received by x component and y component of three-component detector contains fast wave and slow wave simultaneously- Separating fast wave and slow wave and then calculating the anisotropic parameters of media are an important step in multi-component data processing. The authors introduce the Pearson correlation coefficients into multi-component seismic exploration and propose the Pearson correlation coefficients to detect the rotation angle and then separate the fast wave and slow wave. Compared with the traditional cross-correlation method, the Pearson correlation coefficient method is better in accuracy, noise immunity and computational efficiency.

  16. A correlation of thin lens approximation to thick lens design by using context based method in optics education

    Science.gov (United States)

    Farsakoglu, O. F.; Inal Atik, Ipek; Kocabas, Hikmet

    2014-07-01

    The effect of Coddington factors on aberration functions has been analysed using thin lens approximation with optical glass parameters. The dependence of spherical aberration on Coddington shape factor for the various optical glasses in real lens design was discussed using exact ray tracing for the optics education and training purposes. Thin lens approximation and thick lens design are generally taught with only lecturing method. But, thick lens design is closely related to the real life. Hence, it is more appropriate to teach thin lens approximation and thick lens design with real-life context based approach. Context based teaching can be effective in solving problems in which the subject is very difficult and irrelevant. It also provides extensive evidence for optics education that students are generally unable to correctly apply the concepts of lens design to optical instruments currently used. Therefore, the outline of real-life context based thick lens design lessons were proposed and explained in detail considering thin lens approximation.

  17. Correlative imaging across microscopy platforms using the fast and accurate relocation of microscopic experimental regions (FARMER) method

    Science.gov (United States)

    Huynh, Toan; Daddysman, Matthew K.; Bao, Ying; Selewa, Alan; Kuznetsov, Andrey; Philipson, Louis H.; Scherer, Norbert F.

    2017-05-01

    Imaging specific regions of interest (ROIs) of nanomaterials or biological samples with different imaging modalities (e.g., light and electron microscopy) or at subsequent time points (e.g., before and after off-microscope procedures) requires relocating the ROIs. Unfortunately, relocation is typically difficult and very time consuming to achieve. Previously developed techniques involve the fabrication of arrays of features, the procedures for which are complex, and the added features can interfere with imaging the ROIs. We report the Fast and Accurate Relocation of Microscopic Experimental Regions (FARMER) method, which only requires determining the coordinates of 3 (or more) conspicuous reference points (REFs) and employs an algorithm based on geometric operators to relocate ROIs in subsequent imaging sessions. The 3 REFs can be quickly added to various regions of a sample using simple tools (e.g., permanent markers or conductive pens) and do not interfere with the ROIs. The coordinates of the REFs and the ROIs are obtained in the first imaging session (on a particular microscope platform) using an accurate and precise encoded motorized stage. In subsequent imaging sessions, the FARMER algorithm finds the new coordinates of the ROIs (on the same or different platforms), using the coordinates of the manually located REFs and the previously recorded coordinates. FARMER is convenient, fast (3-15 min/session, at least 10-fold faster than manual searches), accurate (4.4 μm average error on a microscope with a 100x objective), and precise (almost all errors are diverse set of samples and imaging methods: live mammalian cells at different time points; fixed bacterial cells on two microscopes with different imaging modalities; and nanostructures on optical and electron microscopes. FARMER can be readily adapted to any imaging system with an encoded motorized stage and can facilitate multi-session and multi-platform imaging experiments in biology, materials science

  18. Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Correia Luis C. L.

    2003-01-01

    Full Text Available OBJECTIVE: To evaluate the performance of the turbidimetric method of C-reactive protein (CRP as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS. METHODS: Serum samples obtained at hospital arrival from 68 patients (66±11 years, 40 men, admitted with unstable angina or non-ST elevation acute myocardial infarction were used to measure CRP by the methods of nephelometry and turbidimetry. RESULTS: The medians of C-reactive protein by the turbidimetric and nephelometric methods were 0.5 mg/dL and 0.47 mg/dL, respectively. A strong linear association existed between the 2 methods, according to the regression coefficient (b=0.75; 95% C.I.=0.70-0.80 and correlation coefficient (r=0.96; P<0.001. The mean difference between the nephelometric and turbidimetric CRP was 0.02 ± 0.91 mg/dL, and 100% agreement between the methods in the detection of high CRP was observed. CONCLUSION: In patients with non-ST elevation ACS, CRP values obtained by turbidimetry show a strong linear association with the method of nephelometry and perfect agreement in the detection of high CRP.

  19. A new field-of-view autotracking method based on back-projected ray image cross-correlation for online tomography reconstruction.

    Science.gov (United States)

    Tomonaga, Sachihiko; Baba, Misuzu; Baba, Norio

    2014-11-01

    In general, a tomogram cannot be observed immediately after the acquisition of a series of specimen tilt images, but is instead observed after the post-processing of the tilt series alignment, which often requires a substantial amount of time. Moreover, for general specimens, the automatic acquisition of the tilt series is difficult because field-of-view tracking frequently fails as the tilt angle or specimen thickness increases.In this study, we focus on the improvement of the field-of-view autotracking technique for the purpose of online tomography reconstruction and propose a new alternative technique [1,2]. The method we proposed uses a so-called 'back-projected ray image' instead of a specimen tilt image. The back-projected ray image is a cross-section image calculated from each projection image only during reconstruction. As a result of a study on 'ray images', the quality and accuracy of the cross-correlation between a pair of neighboring ray images among the tilt series were observed to be very high compared with those between a pair of projection images. We observed that a back projected ray image reliably cross-correlates with other neighboring ray images at the position of an existing three-dimensional object. The proposed method can therefore consistently track the field-of-view, overcoming the weakness of a conventional image-matching-based method. In addition, the present method is simple, and high speed processing is expected to be achieved because fast Fourier transform (FFT) and inverse fast Fourier transform (IFFT) algorithms can be used.We applied this method to real specimens in online experiments using a TEM and thereby demonstrated its successful performance. Online autotracking experiments with thin-section samples were used to demonstrate the effectiveness of the proposed method. The field-of-view was automatically tracked with high accuracy through a tilt angle range. Furthermore, online tomograms were obtained immediately after the last

  20. Correlation of severity of aphasia with cerebral blood flow. A study with /sup 133/Xe inhalation method

    Energy Technology Data Exchange (ETDEWEB)

    Tagawa, Koichi; Sugimoto, Keiko; Sone, Noriaki; Yamaguchi, Takenori; Naritomi, Hiroaki; Sawada, Tohru (National Cardiovascular Center, Suita, Osaka (Japan))

    1982-11-01

    In 46 patients with aphasia due to cerebral infarction, regional cerebral blood flow (rCBF) was measured by /sup 133/Xe inhalation method, and relationship between severity of aphasia and degree of rCBF reduction was investigated. Measurements of rCBF were performed after 2 months of ictus in all patients. At the time of rCBF measurements, the severity of aphasia was mild in 13, moderate in 16 and severe in the other 17 patients. Control rCBF values were obtained from 16 subjects who had neither neurological deficits nor abnormal findings on CT scan. In control group, mean hemispheric rCBF values (mCBF), which were calculated from initial slope index, were 49.1 +- 3.8 and 49.4 +- 3.9 respectively in the right and left hemisphere. In all aphasic patients but two who had mild aphasia, mCBF in the left hemisphere showed lower values as compared to that in the right hemisphere. The mCBF in the left hemisphere was 46.5 +- 5.3 in the mild group, 41.3 +- 5.8 in the moderate group and 34.3 +- 5.0 in the severe group. The values in the moderate and severe groups were significantly reduced as compared to the control or those in the mild group. The mCBF in the severe group was also significantly lower than those in the moderate group. The mCBF in the right hemisphere was 48.4 +- 6.3 in the mild group, 45.6 +- 6.1 in the moderate group and 38.6 +- 4.9 in the severe group. The values in the severe group were significantly reduced as compared to those in the other groups as well as the control. The present study suggests that measurements of rCBF by /sup 133/Xe inhalation method are valid for the evaluation of severity of aphasia in stroke patients.

  1. Optical correlation

    NARCIS (Netherlands)

    Boden, J.A.

    1974-01-01

    A survey is given of the most common types of coherent optical correlators, which are classified as spatial plane correlators, frequency plane correlators and special reference correlators. Only the spatial plane correlators are dealt with rather thoroughly. Basic principles, some special features,

  2. Correlation between Photoluminescence and Carrier Transport and a Simple In Situ Passivation Method for High-Bandgap Hybrid Perovskites.

    Science.gov (United States)

    Stoddard, Ryan J; Eickemeyer, Felix T; Katahara, John K; Hillhouse, Hugh W

    2017-07-20

    High-bandgap mixed-halide hybrid perovskites have higher open-circuit voltage deficits and lower carrier diffusion lengths than their lower-bandgap counterparts. We have developed a ligand-assisted crystallization (LAC) technique that introduces additives in situ during the solvent wash and developed a new method to dynamically measure the absolute intensity steady-state photoluminescence and the mean carrier diffusion length simultaneously. The measurements reveal four distinct regimes of material changes and show that photoluminescence brightening often coincides with losses in carrier transport, such as in degradation or phase segregation. Further, the measurements enabled optimization of LAC on the 1.75 eV bandgap FA0.83Cs0.17Pb(I0.66Br0.34)3, resulting in an enhancement of the photoluminescence quantum yield (PLQY) of over an order of magnitude, an increase of 80 meV in the quasi-Fermi level splitting (to 1.29 eV), an increase in diffusion length by a factor of 3.5 (to over 1 μm), and enhanced open-circuit voltage and short-circuit current from photovoltaics fabricated from the LAC-treated films.

  3. Magnetic behavior of iron-modified MCM-41 correlated with clustering processes from the wet impregnation method

    Energy Technology Data Exchange (ETDEWEB)

    Cuello, Natalia I.; Elías, Verónica R. [Centro de Investigación y Tecnología Química (CITeQ) (UTN-CONICET), Facultad Regional Córdoba. Maestro López y Cruz Roja Argentina, Ciudad Universitaria, Córdoba 5016 (Argentina); Winkler, Elin [Centro Atómico Bariloche, Comisión Nacional de Energía Atómica – CONICET, Avenue Bustillo 9500, San Carlos de Bariloche 8400 (Argentina); Pozo-López, Gabriela; Oliva, Marcos I. [Facultad de Matemática, Astronomía y Física, Universidad Nacional de Córdoba – IFEG, CONICET, Ciudad Universitaria, Córdoba 5000 (Argentina); Eimer, Griselda A., E-mail: geimer@frc.utn.edu.ar [Centro de Investigación y Tecnología Química (CITeQ) (UTN-CONICET), Facultad Regional Córdoba. Maestro López y Cruz Roja Argentina, Ciudad Universitaria, Córdoba 5016 (Argentina)

    2016-06-01

    Magnetic MCM-41 type mesoporous silica materials were synthetized and modified with different iron loadings by the wet impregnation method. The evolution of iron speciation, depending on the metal loading and associated with a particular magnetic behavior was investigated by M vs. H curves, FC–ZFC curves, EPR spectroscopy and other complementary techniques such as SEM, TEM, and chemisorption of pyridine followed by FT-IR studies. A superparamagnetic contribution was larger for the lower loadings suggesting the high dispersion of very small sized iron nanospecies. However, this contribution decreased with increasing metal loading due to the growth of magnetically blocked nanoparticles (hematite) on the outer surface. Finally, a bimodal size distribution for the superparamagnetic nanospecies could be inferred; then the anisotropy constant for this phase and the corresponding nanospecies sizes were estimated. - Highlights: • All samples showed a main superparamagnetic contribution. • The oxide particles grow at expense of superparamagnetic nanospecies. • Bimodal distribution of nanospecies in superparamagnetic regime was determined. • The anisotropy constant for superparamagnetic nanospecies was calculated.

  4. ORIGINAL ARTICLE: Detection of β-Lactamase Activity in Various Clinical Bacterial Isolates by Three Different Methods and its Correlation with Drug Resistance.

    Directory of Open Access Journals (Sweden)

    Sanjay M Wavare

    2012-07-01

    Full Text Available Background: β-lactams such as penicillins are the most widely used antibiotics, and β-lactamases are the greatest source of resistance to penicillins. Aims and Objectives: To study β-lactamase production in clinical isolates of family Enterobacteriaceae, P. aeruginosa and Staphylococci by three different methods and to correlate its potential with drug resistance; with an endeavour to evaluate convenient and economical method duly supported by relevant Minimum Inhibitory Concentration (MIC studies. Material and Methods: Total 240 clinical isolates (Gram-negative bacilli-191, staphylococci-49 were subjected to antimicrobial susceptibility testing by Kirby-Bauer disk diffusion method and MIC for ampicillin and penicillin was determined by agar dilution method. β-lactamase was detected by broth acidometric, iodometric cell suspension and microbiological method. Results: Multidrug resistance was observed in more than 90% isolates. One hundred and ninety Gram-negative bacilli were resistant to ampicillin and 47 staphylococcal isolates were resistant to both penicillin and ampicillin. Though microbiological method gave highest positive results 210 (87.5%, iodometric method could detect β-lactamase in apparently sensitive isolates as well giving satisfactory [207 (86.25%] comparable results. Conclusion: In view of the noted bacterial resistance, tests for β-lactamase should be carried out on a routine basis for an early implementation of appropriate antimicrobial therapy. Iodometric method is eminently convenient, economical and reliable method. Isolates showing MIC <0.125µg/ml for penicillin and MIC <8µg/ml for ampicillin should be checked for β-lactamase production.

  5. Determination of interaction potentials of colloidal monolayers from the inversion of pair correlation functions: a two-dimensional predictor-corrector method.

    Science.gov (United States)

    Law, A D; Buzza, D M A

    2009-09-07

    The structure and stability of colloidal monolayers depend crucially on the effective pair potential u(r) between colloidal particles. In this paper, we develop a two-dimensional (2D) predictor-corrector method for extracting u(r) from the pair correlation function g(r) of dense colloidal monolayers. The method is based on an extension of the three-dimensional scheme of Rajagopalan and Rao [Phys. Rev. E 55, 4423 (1997)] to 2D by replacing the unknown bridge function B(r) with the hard-disk bridge function B(d)(r); the unknown hard-disk diameter d is then determined using an iterative scheme. We compare the accuracy of our predictor-corrector method to the conventional one-step inversion schemes of hypernetted chain closure (HNC) and Percus-Yevick (PY) closure. Specifically we benchmark all three schemes against g(r) data generated from Monte Carlo simulation for a range of 2D potentials: exponential decay, Stillinger-Hurd, Lennard-Jones, and Derjaguin-Landau-Verwey-Overbeek. We find that for all these potentials, the predictor-corrector method is at least as good as the most accurate one-step method for any given potential, and in most cases it is significantly better. In contrast the accuracy of the HNC and PY methods relative to each other depends on the potential studied. The proposed predictor-corrector scheme is therefore a robust and more accurate alternative to these conventional one-step inversion schemes.

  6. Electronically Excited States of Vitamin B12: Benchmark Calculations Including Time-Dependent Density Functional Theory and Correlated Ab Initio Methods

    CERN Document Server

    Kornobis, Karina; Wong, Bryan M; Lodowski, Piotr; Jaworska, Maria; Andruniów, Tadeusz; Rudd, Kenneth; Kozlowski, Pawel M; 10.1021/jp110914y

    2011-01-01

    Time-dependent density functional theory (TD-DFT) and correlated ab initio methods have been applied to the electronically excited states of vitamin B12 (cyanocobalamin or CNCbl). Different experimental techniques have been used to probe the excited states of CNCbl, revealing many issues that remain poorly understood from an electronic structure point of view. Due to its efficient scaling with size, TD-DFT emerges as one of the most practical tools that can be used to predict the electronic properties of these fairly complex molecules. However, the description of excited states is strongly dependent on the type of functional used in the calculations. In the present contribution, the choice of a proper functional for vitamin B12 was evaluated in terms of its agreement with both experimental results and correlated ab initio calculations. Three different functionals, i.e. B3LYP, BP86, and LC-BLYP, were tested. In addition, the effect of relative contributions of DFT and HF to the exchange-correlation functional ...

  7. Study on correlation among three kinds of bilirubin detection method%三种胆红素检测方法相关性研究

    Institute of Scientific and Technical Information of China (English)

    李守卫; 姚强

    2013-01-01

    目的 探讨三种胆红素检测方法的相关性.方法 选取生后7d内目测存在黄疸的住院新生儿50例,抽取血清标本用生化法测定血清总胆红素值,并同步以微量法和经皮法测定胆红素值,分别计算经皮胆红素值(TcB)与静脉血总胆红素值、末梢微量血胆红素值、静脉血总胆红素值之间的相关系数、检验其统计学意义.结果 末梢微量血胆红素检测法、经皮胆红素检测法分别与静脉血生化法均有很好的相关性(r=0.948、0.935,均P<0.01),并且末梢微量血胆红素检测法与静脉血生化法相关性更好.结论 采用微量血测定法检测胆红素值,不失为一种操作简便、结果可靠的方法.%Objective To explore which operation and the accuracy of the detection method is better by exploring the correlation among three bilirubin detection methods.Methods 50 hospitalized neonates within 7 days after birth with visual jaundice were randomly selected.The total serum bilirubin level was measured by the routine laboratory method.At the same time,the serum bilirubin level was measured by bilirubin analyzer for capillary blood and transcutaneous bilirubin(TcB) measurement,then calculated the linear correlation coefficient of TcB level and TSB level,capillary blood bilirubin level and TSB level respectively to analyze their statistical significance,and get the linear regression model at last.Results Close correlation is existed between the capillary blood bilirubin measurement and the routine laboratory method,also the transcutaneous bilirubin measurement and the routine laboratory method.Moreover,the former is better than the later.Conclusion Capillary blood bilirubin is reliable in measuring serum bilirubin level of newborns.

  8. An empirical comparison of methods for analyzing correlated data from a discrete choice survey to elicit patient preference for colorectal cancer screening

    Directory of Open Access Journals (Sweden)

    Cheng Ji

    2012-02-01

    Full Text Available Abstract Background A discrete choice experiment (DCE is a preference survey which asks participants to make a choice among product portfolios comparing the key product characteristics by performing several choice tasks. Analyzing DCE data needs to account for within-participant correlation because choices from the same participant are likely to be similar. In this study, we empirically compared some commonly-used statistical methods for analyzing DCE data while accounting for within-participant correlation based on a survey of patient preference for colorectal cancer (CRC screening tests conducted in Hamilton, Ontario, Canada in 2002. Methods A two-stage DCE design was used to investigate the impact of six attributes on participants' preferences for CRC screening test and willingness to undertake the test. We compared six models for clustered binary outcomes (logistic and probit regressions using cluster-robust standard error (SE, random-effects and generalized estimating equation approaches and three models for clustered nominal outcomes (multinomial logistic and probit regressions with cluster-robust SE and random-effects multinomial logistic model. We also fitted a bivariate probit model with cluster-robust SE treating the choices from two stages as two correlated binary outcomes. The rank of relative importance between attributes and the estimates of β coefficient within attributes were used to assess the model robustness. Results In total 468 participants with each completing 10 choices were analyzed. Similar results were reported for the rank of relative importance and β coefficients across models for stage-one data on evaluating participants' preferences for the test. The six attributes ranked from high to low as follows: cost, specificity, process, sensitivity, preparation and pain. However, the results differed across models for stage-two data on evaluating participants' willingness to undertake the tests. Little within

  9. Linear scaling explicitly correlated MP2-F12 and ONIOM methods for the long-range interactions of the nanoscale clusters in methanol aqueous solutions.

    Science.gov (United States)

    Li, Wei

    2013-01-07

    A linear scaling quantum chemistry method, generalized energy-based fragmentation (GEBF) approach has been extended to the explicitly correlated second-order Møller-Plesset perturbation theory F12 (MP2-F12) method and own N-layer integrated molecular orbital molecular mechanics (ONIOM) method, in which GEBF-MP2-F12, GEBF-MP2, and conventional density functional tight-binding methods could be used for different layers. Then the long-range interactions in dilute methanol aqueous solutions are studied by computing the binding energies between methanol molecule and water molecules in gas-phase and condensed phase methanol-water clusters with various sizes, which were taken from classic molecular dynamics (MD) snapshots. By comparing with the results of force field methods, including SPC, TIP3P, PCFF, and AMOEBA09, the GEBF-MP2-F12 and GEBF-ONIOM methods are shown to be powerful and efficient for studying the long-range interactions at a high level. With the GEBF-ONIOM(MP2-F12:MP2) and GEBF-ONIOM(MP2-F12:MP2:cDFTB) methods, the diameters of the largest nanoscale clusters under studies are about 2.4 nm (747 atoms and 10 209 basis functions with aug-cc-pVDZ basis set) and 4 nm (3351 atoms), respectively, which are almost impossible to be treated by conventional MP2 or MP2-F12 method. Thus, the GEBF-F12 and GEBF-ONIOM methods are expected to be a practical tool for studying the nanoscale clusters in condensed phase, providing an alternative benchmark for ab initio and density functional theory studies, and developing new force fields by combining with classic MD simulations.

  10. Comparing Single Molecule Tracking and correlative approaches: an application to the datasets recently presented in Nature Methods by Chenuard et al

    CERN Document Server

    di Rienzo, Carmine

    2016-01-01

    Recent efforts to survey the numerous softwares available to perform single molecule tracking (SMT) highlighted a significant dependence of the outcomes on the specific method used, and the limitation encountered by most techniques to capture fast movements in a crowded environment. Other approaches to identify the mode and rapidity of motion of fluorescently labeled biomolecules, that do not relay on the localization and linking of the images of isolated single molecules are, however, available.This direct comparison shows that correlative imaging analysis approaches complement effectively current SMT methods in circumstances when, due to either the density of the sample, the low signal to noise ratio or molecular blinking, trajectory linking does not allow to capture long-range or fast motion.

  11. Statistical correlation of the soil incubation and the accelerated laboratory extraction methods to estimate nitrogen release rates of slow- and controlled-release fertilizers.

    Science.gov (United States)

    Medina, L Carolina; Sartain, Jerry; Obreza, Thomas; Hall, William L; Thiex, Nancy J

    2014-01-01

    Several technologies have been proposed to characterize the nutrient release patterns of enhanced-efficiency fertilizers (EEFs) during the last few decades. These technologies have been developed mainly by manufacturers and are product-specific based on the regulation and analysis of each EEF product. Despite previous efforts to characterize nutrient release of slow-release fertilizer (SRF) and controlled-release fertilizer (CRF) materials, no official method exists to assess their nutrient release patterns. However, the increased production and distribution of EEFs in specialty and nonspecialty markets requires an appropriate method to verify nutrient claims and material performance. Nonlinear regression was used to establish a correlation between the data generated from a 180-day soil incubation-column leaching procedure and 74 h accelerated lab extraction method, and to develop a model that can predict the 180-day nitrogen (N) release curve for a specific SRF and CRF product based on the data from the accelerated laboratory extraction method. Based on the R2 > 0.90 obtained for most materials, results indicated that the data generated from the 74 h accelerated lab extraction method could be used to predict N release from the selected materials during 180 days, including those fertilizers that require biological activity for N release.

  12. The Assessment of Parameters Affecting the Quality of Cord Blood by the Appliance of the Annexin V Staining Method and Correlation with CFU Assays.

    Science.gov (United States)

    Radke, Teja Falk; Barbosa, David; Duggleby, Richard Charles; Saccardi, Riccardo; Querol, Sergio; Kögler, Gesine

    2013-01-01

    The assessment of nonviable haematopoietic cells by Annexin V staining method in flow cytometry has recently been published by Duggleby et al. Resulting in a better correlation with the observed colony formation in methylcellulose assays than the standard ISHAGE protocol, it presents a promising method to predict cord blood potency. Herein, we applied this method for examining the parameters during processing which potentially could affect cord blood viability. We could verify that the current standards regarding time and temperature are sufficient, since no significant difference was observed within 48 hours or in storage at 4°C up to 26°C. However, the addition of DMSO for cryopreservation alone leads to an inevitable increase in nonviable haematopoietic stem cells from initially 14.8% ± 4.3% to at least 30.6% ± 5.5%. Furthermore, CFU-assays with varied seeding density were performed in order to evaluate the applicability as a quantitative method. The results revealed that only in a narrow range reproducible clonogenic efficiency (ClonE) could be assessed, giving at least a semiquantitative estimation. We conclude that both Annexin V staining method and CFU-assays with defined seeding density are reliable means leading to a better prediction of the final potency. Especially Annexin V, due to its fast readout, is a practical tool for examining and optimising specific steps in processing, while CFU-assays add a functional confirmation.

  13. An empirical comparison of methods for analyzing correlated data from a discrete choice survey to elicit patient preference for colorectal cancer screening.

    Science.gov (United States)

    Cheng, Ji; Pullenayegum, Eleanor; Marshall, Deborah A; Marshall, John K; Thabane, Lehana

    2012-02-20

    A discrete choice experiment (DCE) is a preference survey which asks participants to make a choice among product portfolios comparing the key product characteristics by performing several choice tasks. Analyzing DCE data needs to account for within-participant correlation because choices from the same participant are likely to be similar. In this study, we empirically compared some commonly-used statistical methods for analyzing DCE data while accounting for within-participant correlation based on a survey of patient preference for colorectal cancer (CRC) screening tests conducted in Hamilton, Ontario, Canada in 2002. A two-stage DCE design was used to investigate the impact of six attributes on participants' preferences for CRC screening test and willingness to undertake the test. We compared six models for clustered binary outcomes (logistic and probit regressions using cluster-robust standard error (SE), random-effects and generalized estimating equation approaches) and three models for clustered nominal outcomes (multinomial logistic and probit regressions with cluster-robust SE and random-effects multinomial logistic model). We also fitted a bivariate probit model with cluster-robust SE treating the choices from two stages as two correlated binary outcomes. The rank of relative importance between attributes and the estimates of β coefficient within attributes were used to assess the model robustness. In total 468 participants with each completing 10 choices were analyzed. Similar results were reported for the rank of relative importance and β coefficients across models for stage-one data on evaluating participants' preferences for the test. The six attributes ranked from high to low as follows: cost, specificity, process, sensitivity, preparation and pain. However, the results differed across models for stage-two data on evaluating participants' willingness to undertake the tests. Little within-patient correlation (ICC ≈ 0) was found in stage-one data, but

  14. A Method to Correlate mRNA Expression Datasets Obtained from Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Tissue Samples: A Matter of Thresholds.

    Directory of Open Access Journals (Sweden)

    Dana A M Mustafa

    Full Text Available Gene expression profiling of tumors is a successful tool for the discovery of new cancer biomarkers and potential targets for the development of new therapeutic strategies. Reliable profiling is preferably performed on fresh frozen (FF tissues in which the quality of nucleic acids is better preserved than in formalin-fixed paraffin-embedded (FFPE material. However, since snap-freezing of biopsy materials is often not part of daily routine in pathology laboratories, one may have to rely on archival FFPE material. Procedures to retrieve the RNAs from FFPE materials have been developed and therefore, datasets obtained from FFPE and FF materials need to be made compatible to ensure reliable comparisons are possible.To develop an efficient method to compare gene expression profiles obtained from FFPE and FF samples using the same platform.Twenty-six FFPE-FF sample pairs of the same tumors representing various cancer types, and two FFPE-FF sample pairs of breast cancer cell lines, were included. Total RNA was extracted and gene expression profiling was carried out using Illumina's Whole-Genome cDNA-mediated Annealing, Selection, extension and Ligation (WG-DASL V3 arrays, enabling the simultaneous detection of 24,526 mRNA transcripts. A sample exclusion criterion was created based on the expression of 11 stably expressed reference genes. Pearson correlation at the probe level was calculated for paired FFPE-FF, and three cut-off values were chosen. Spearman correlation coefficients between the matched FFPE and FF samples were calculated for three probe lists with varying levels of significance and compared to the correlation based on all measured probes. Unsupervised hierarchical cluster analysis was performed to verify performance of the included probe lists to compare matched FPPE-FF samples.Twenty-seven FFPE-FF pairs passed the sample exclusion criterion. From the profiles of 27 FFPE and FF matched samples, the best correlating probes were identified

  15. An Improved Phase Correlation Method for Obtaining Dynamic Feature of the Ocean from Sequential SAR Sub-aperture Images (in English

    Directory of Open Access Journals (Sweden)

    Wang Xiao-qing

    2013-03-01

    Full Text Available Dynamic features are important aspects of the ocean. However the dynamic information is lost in most conventional Synthetic Aperture Radar (SAR image processing methods, because they treat the image as an instantaneous state of the observed area. In fact, we can obtain dynamic features of the ocean from sequential sub-aperture images, because we know that the different parts of the azimuthal aperture correspond to different imaging instances. A key step for retrieving the dynamic features from sequential images is image-matching. However, the heavy noise characteristic of sub-aperture SAR images renders the traditional image-matching methods ineffective. In this paper we propose an image matching method based on improved phase correlation to deal with the heavy noise problem of SAR sub-aperture images. Experimental results show that the improved image-matching method presents an accuracy of 0.15 pixel and noise robustness. The analysis indicates that the improved algorithm is competent for obtaining dynamic information from the medium resolution airborne SAR images or high resolution spaceborne SAR images with 0.15-0.3 m/s estimation precision under most SNR conditions. The improved algorithm was used on an airborne SAR data to retrieve the movement velocity. The retrieved velocity ranged from 0.05-0.5 m/s, which seems to be reasonable value for the ocean current velocity.

  16. Scalable electron correlation methods I.: PNO-LMP2 with linear scaling in the molecular size and near-inverse-linear scaling in the number of processors.

    Science.gov (United States)

    Werner, Hans-Joachim; Knizia, Gerald; Krause, Christine; Schwilk, Max; Dornbach, Mark

    2015-02-10

    We propose to construct electron correlation methods that are scalable in both molecule size and aggregated parallel computational power, in the sense that the total elapsed time of a calculation becomes nearly independent of the molecular size when the number of processors grows linearly with the molecular size. This is shown to be possible by exploiting a combination of local approximations and parallel algorithms. The concept is demonstrated with a linear scaling pair natural orbital local second-order Møller-Plesset perturbation theory (PNO-LMP2) method. In this method, both the wave function manifold and the integrals are transformed incrementally from projected atomic orbitals (PAOs) first to orbital-specific virtuals (OSVs) and finally to pair natural orbitals (PNOs), which allow for minimum domain sizes and fine-grained accuracy control using very few parameters. A parallel algorithm design is discussed, which is efficient for both small and large molecules, and numbers of processors, although true inverse-linear scaling with compute power is not yet reached in all cases. Initial applications to reactions involving large molecules reveal surprisingly large effects of dispersion energy contributions as well as large intramolecular basis set superposition errors in canonical MP2 calculations. In order to account for the dispersion effects, the usual selection of PNOs on the basis of natural occupation numbers turns out to be insufficient, and a new energy-based criterion is proposed. If explicitly correlated (F12) terms are included, fast convergence to the MP2 complete basis set (CBS) limit is achieved. For the studied reactions, the PNO-LMP2-F12 results deviate from the canonical MP2/CBS and MP2-F12 values by <1 kJ mol(-1), using triple-ζ (VTZ-F12) basis sets.

  17. Practical method of quantifying cerebral blood flow using arterial spin labeling. Numerical simulation and correlation of pulsed ASL and cold xenon-CT CBF

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, Tokunori [Toshiba Corp., Otawara, Tochigi (Japan). Medical Systems R and D Center; Takahashi, Kiyohiko; Nozokido, Takeshi; Sato, Takaaki; Naito, Isao; Takatama, Shin [Geriatrics Research Inst. and Hospital, Gunma (Japan); Iwai, Tomoyuki [Suwa Central Hospital, Chino, Nagano (Japan)

    2002-07-01

    Currently arterial spin labeling (ASL) is not used in clinical practice even though various studies have been carried out on quantifying cerebral blood flow (CBF) by magnetic resonance (MR) perfusion imaging using ASL. In the following study, we evaluated the relationship between ASL signals and cerebral blood flow both numerically and experimentally. When evaluating the relationship numerically we used simulation based on the two-compartment model. We evaluated experimentally by using the correlation of pulsed ASL (PASL) signals with the CBF measured by cold xenon-CT (Xe-CT) in the human brain. Based on the results, we propose a practical linear scaling method for quantifying CBF values using a single TI pulsed ASL image. Numerical simulation using the two-compartment model, which was considered to model reality more closely than the conventional single-compartment model, showed that the ASL signal was correlated almost linearly in the CBF range (<100[ml/100 cc/min]). The ASL signal was also stronger in variations of model parameters, such as the relaxation time in extravascular space (T{sub 1e}), intravascular volume (CBV), and the brain-blood partition coefficient, than when the conventional single-compartment model was used. A linear correlation between the ASL signal and the absolute CBF value was also found in the PASL and Xe-CT experiments. This indicates that it may be possible to quantify CBF values using only a single TI pulsed ASL image. The proposed method requires reference CBF data (Xe-CT, SPECT, PET data or flow phantom data) or both a control image and conversion table obtained by simulation calculations. Although the ASL signals depend on the MRI hardware and imaging conditions, once the scaling coefficient K is calculated, the ASL signals can be converted to corresponding CBF values. Further studies are required in patients with ischemic conditions because the arterial transit delay time cannot be ignored in these patients. The proposed method can

  18. Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: Correlation with VEGF expression

    Energy Technology Data Exchange (ETDEWEB)

    Chen, T.-W. [Department of Radiology, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041 (China) and Sichuan Province Key Laboratory of Medical Imaging and Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 63 Wen Hua Lu, Nanchong, Sichuan 637000 (China); Yang, Z.-G., E-mail: yangzg1117@yahoo.com.cn [Department of Radiology, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041 (China); State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041 (China); Chen, H.-J. [Department of Pathology, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041 (China); Li, Y.; Tang, S.-S.; Yao, J.; Dong, Z.-H. [Department of Radiology, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041 (China); He, D. [Department of Pathology, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041 (China)

    2012-08-15

    Aim: To investigate the correlation between vascular endothelial cell growth factor (VEGF) expression and first-pass perfusion parameters at multidetector computed tomography (MDCT) using a low-dose technique, and to determine how to discriminate VEGF positivity from VEGF negativity by perfusion CT in oesophageal squamous cell carcinomas. Materials and methods: Thirty-two patients with oesophageal squamous cell carcinomas underwent first-pass perfusion with 64-section MDCT at 50 mAs. Perfusion parameters, including perfusion, peak enhanced density (PED), time to peak (TTP), and blood volume (BV), were measured. Postoperative specimens were assessed for VEGF expression. Correlation tests were performed to determine the associations between each CT perfusion parameter and VEGF expression. The cut-off values of perfusion parameters were obtained statistically to discriminate VEGF positivity from VEGF negativity. Results: Mean perfusion, PED, TTP, and BV were 38.47 {+-} 30.26 ml/min/ml, 24.68 {+-} 9.65 HU, 28.35 {+-} 9.03 s, and 11.82 {+-} 6.06 ml/100 g, respectively. PED or BV were significantly higher in the VEGF-positive group than in the VEGF-negative group (all p < 0.05), but no significant difference in perfusion or TTP was found between the VEGF-positive and VEGF-negative groups (all p > 0.05). In VEGF positivity, PED and BV were correlated with VEGF expression (r = 0.576 and 0.765, respectively; all p < 0.05), whereas perfusion and TTP were not (r = 0.361 and 0.239, respectively; all p > 0.05). A threshold of BV (10.23 ml/100 g) achieved a sensitivity of 94.4%, and a specificity of 92.9% for discriminating VEGF positivity from VEGF negativity. Conclusion: BV could reflect tumour VEGF expression, and could be an indicator for evaluating angiogenesis in oesophageal tumours.

  19. Parents' knowledge, attitudes, use of pain relief methods and satisfaction related to their children's postoperative pain management: a descriptive correlational study.

    Science.gov (United States)

    Chng, Hui Yi; He, Hong-Gu; Chan, Sally Wai-Chi; Liam, Joanne Li Wee; Zhu, Lixia; Cheng, Karis Kin Fong

    2015-06-01

    To examine parents' knowledge about and attitudes towards pain management, use of pain relief strategies and satisfaction with their children's postoperative pain management, as well as the relationships among these variables. Children's postoperative pain is inadequately managed worldwide. Despite increasing emphasis on parental involvement in children's postoperative pain management, few studies have examined parents' management of their child's postoperative pain in Singapore. A descriptive correlational study. A convenience sample of 60 parents having 6- to 14-year-old children undergoing inpatient elective surgery in a public hospital in Singapore was recruited. Data were collected one day after each child's surgery using the Pain Management Knowledge and Attitudes questionnaire and the Parents' Use of Pain Relief Strategies questionnaire. Descriptive statistics, Mann-Whitney U tests, Kruskal-Wallis tests and Spearman's rank correlation coefficient were used for data analyses. Parents displayed moderate levels of knowledge, attitudes and use of pain relief methods in relation to their children's postoperative pain and pain management. They were generally satisfied with the management of their child's postoperative pain. There was significant difference in Parents' Use of Pain Relief Strategies scores between parents with and without previous experience of caring for their hospitalised child. Statistically significant positive correlations were found between parents' knowledge and attitude, knowledge and satisfaction, attitude and satisfaction, knowledge and pain relief strategies, as well as attitude and pain relief strategies. This study indicates the need to provide parents with more information regarding their children's postoperative pain management. Future studies are needed to develop educational interventions for parents to improve their knowledge and attitudes, which will eventually improve their use of pain relief strategies for their children. Health

  20. 情景环境与人为差错的对应关系分析方法%Method for correlation analysis between scenario and human error

    Institute of Scientific and Technical Information of China (English)

    蒋英杰; 孙志强; 宫二玲; 谢红卫

    2011-01-01

    A new method is proposed to analyze the correlation between scenario and human error. The scenario is decomposed into six aspects, which are operator, machine, task, organization, environment and assistant devices. Based on the scenario decomposition, a taxonomy of performance shaping factor is constructed, which includes thirty-eight items and can provide a reference template for the investigation of human error causes. Based on the skill-based, rule-based and knowledge-based (SRK) model, the slip/lapse/mistake framework is introduced to classify human errors, which are categorized as skill-based slip and lapse, rule-based slip and mistake, and knowledge-based mistake. Grey relational analysis is introduced to analyze the correlation between performance shaping factors and human error types, in which the correlations of "consequent-antecedent" and "antecedent-consequent" are both analyzed. By this method, performance shaping factors related to some specified human error type and human error types caused by some specified performance shaping factor both can be sorted according to their correlation degrees. A case study is provided, which shows that the proposed method is applicable in analyzing the correlation between scenario and human error, and can provide some important implications for human error prediction and human error reduction.%提出了一种分析情景环境与人为差错之间对应关系的方法.将情景环境分为操作者、机器、任务、组织、环境和辅助系统6个方面,建立了包含38个元素的行为形成因子分类方法,为人为差错成因的查找提供了参考模板.在SRK(skill-based,rule-based and knowledge-based)模型的基础上引入疏忽/遗忘/错误分类框架,将人为差错分为技能型疏忽、技能型遗忘、规则型疏忽、规则型错误以及知识型错误等5种基本的人为差错类型.使用灰色关联分析方法,从“结果-原因”和“原因-结果”两个方向分析行为形

  1. A primer of statistical methods for correlating parameters and properties of electrospun poly(l -lactide) scaffolds for tissue engineering-PART 1: Design of experiments

    KAUST Repository

    Seyedmahmoud, Rasoul

    2014-03-20

    Tissue engineering scaffolds produced by electrospinning are of enormous interest, but still lack a true understanding about the fundamental connection between the outstanding functional properties, the architecture, the mechanical properties, and the process parameters. Fragmentary results from several parametric studies only render some partial insights that are hard to compare and generally miss the role of parameters interactions. To bridge this gap, this article (Part-1 of 2) features a case study on poly-l-lactide scaffolds to demonstrate how statistical methods such as design of experiments can quantitatively identify the correlations existing between key scaffold properties and control parameters, in a systematic, consistent, and comprehensive manner disentangling main effects from interactions. The morphological properties (i.e., fiber distribution and porosity) and mechanical properties (Young\\'s modulus) are "charted" as a function of molecular weight (MW) and other electrospinning process parameters (the Xs), considering the single effect as well as interactions between Xs. For the first time, the major role of the MW emerges clearly in controlling all scaffold properties. The correlation between mechanical and morphological properties is also addressed.

  2. Structural and spectroscopic characterization of methyl isocyanate, methyl cyanate, methyl fulminate, and acetonitrile N-oxide using highly correlated ab initio methods

    Science.gov (United States)

    Dalbouha, S.; Senent, M. L.; Komiha, N.; Domínguez-Gómez, R.

    2016-09-01

    Various astrophysical relevant molecules obeying the empirical formula C2H3NO are characterized using explicitly correlated coupled cluster methods (CCSD(T)-F12). Rotational and rovibrational parameters are provided for four isomers: methyl isocyanate (CH3NCO), methyl cyanate (CH3OCN), methyl fulminate (CH3ONC), and acetonitrile N-oxide (CH3CNO). A CH3CON transition state is inspected. A variational procedure is employed to explore the far infrared region because some species present non-rigidity. Second order perturbation theory is used for the determination of anharmonic frequencies, rovibrational constants, and to predict Fermi resonances. Three species, methyl cyanate, methyl fulminate, and CH3CON, show a unique methyl torsion hindered by energy barriers. In methyl isocyanate, the methyl group barrier is so low that the internal top can be considered a free rotor. On the other hand, acetonitrile N-oxide presents a linear skeleton, C3v symmetry, and free internal rotation. Its equilibrium geometry depends strongly on electron correlation. The remaining isomers present a bend skeleton. Divergences between theoretical rotational constants and previous parameters fitted from observed lines for methyl isocyanate are discussed on the basis of the relevant rovibrational interaction and the quasi-linearity of the molecular skeleton.

  3. A nonlinear training set superposition filter derived by neural network training methods for implementation in a shift-invariant optical correlator

    Science.gov (United States)

    Kypraios, Ioannis; Young, Rupert C. D.; Birch, Philip M.; Chatwin, Christopher R.

    2003-08-01

    The various types of synthetic discriminant function (sdf) filter result in a weighted linear superposition of the training set images. Neural network training procedures result in a non-linear superposition of the training set images or, effectively, a feature extraction process, which leads to better interpolation properties than achievable with the sdf filter. However, generally, shift invariance is lost since a data dependant non-linear weighting function is incorporated in the input data window. As a compromise, we train a non-linear superposition filter via neural network methods with the constraint of a linear input to allow for shift invariance. The filter can then be used in a frequency domain based optical correlator. Simulation results are presented that demonstrate the improved training set interpolation achieved by the non-linear filter as compared to a linear superposition filter.

  4. Linkage between passenger demand and surrounding land-use patterns at urban rail transit stations: A canonical correlation analysis method and case study in Chongqing

    Directory of Open Access Journals (Sweden)

    Xin Li

    2016-08-01

    Full Text Available This paper employs a canonical correlation analysis method to quantify the linkage between urban rail transit station demand and the surrounding land-use patterns. It is used to identify key land use variables by evaluating their degrees of contribution to the rail transit station demand. A full month of IC card data and detailed regulatory land use plan from Chongqing, China are collected for model development and validation. The proposed model contributes to offering the capability of targeting key land use patterns and associating them with rail transit station boarding and alighting demand simultaneously. The proposed model can reveal underlying rules between rail transit station demand and land use variables and can be used to evaluate the Transit Oriented Development (TOD plans to improve land use and transit operational efficiency.

  5. A novel auto-correlation function method and FORTRAN codes for the determination of the decay ratio in BWR stability analysis

    Energy Technology Data Exchange (ETDEWEB)

    Behringer, K

    2001-08-01

    A novel auto-correlation function (ACF) method has been investigated for determining the oscillation frequency and the decay ratio in BWR stability analyses. The report describes not only the method but also documents comprehensively the used and developed FORTRAN codes. The neutron signals are band-pass filtered to separate the oscillation peak in the power spectral density (PSD) from background. Two linear second-order oscillation models are considered. The ACF of each model, corrected for signal filtering and with the inclusion of a background term under the peak in the PSD, is then least-squares fitted to the ACF estimated on the previously filtered neutron signals, in order to determine the oscillation frequency and the decay ratio. The procedures of filtering and ACF estimation use fast Fourier transform techniques with signal segmentation. Gliding 'short-time' ACF estimates along a signal record allow the evaluation of uncertainties. Some numerical results are given which have been obtained from neutron signal data offered by the recent Forsmark I and Forsmark II NEA benchmark project. They are compared with those from other benchmark participants using different other analysis methods. (author)

  6. Investigations of high power laser beam interaction with material by means of hybrid FVM-FEM and digital image correlation methods

    Science.gov (United States)

    Kujawińska, M.; Łapka, P.; Malesa, M.; Malowany, K.; Prasek, M.; Marczak, J.

    2016-12-01

    The paper presents the new approach to the analysis of interaction between a high power laser beam and matter. The method relies on the combined experimental-numerical spatio-temporal analysis of temperature, displacement and strain maps which are generated at a surface of an object illuminated by a high power laser beam. Transient heat transfer numerical simulations were carried out applying the FVM, while the quasi-transient structural analyses were performed with the aid of the FEM. The displacement maps were captured by means of 3D Digital Image Correlation method, and temperature maps were provided by a high speed IR camera. The experimental data are compared to the initial model of laser induced heat transfer in an object and resulting displacements/strains. The first approach to hybrid experimental-numerical method which aims in indirect determination of laser beam profile is described. The monitoring of displacement/strain maps directly at an illuminated object may be also used for a structural integrity analysis of a target. In the paper at first the numerical simulations applied to model laser beam thermal interaction with solid bodies are presented. Next the laboratory experimental stand is described and the results of the initial tests performed at aluminum and bronze samples are shown and compared with numerical simulations. The advantages and disadvantages of the proposed methodology are discussed in relation to the two applications mentioned above.

  7. Validation of a stability-indicating RP-LC method for the assessment of recombinant human interleukin-11 and its correlation with bioassay.

    Science.gov (United States)

    Souto, Ricardo Bizogne; Stamm, Fernanda Pavani; Ribela, Maria Teresa de Carvalho Pinto; Bartolini, Paolo; Calegari, Guilherme Zanini; Dalmora, Sérgio Luiz

    2012-01-01

    A stability-indicating reversed-phase liquid chromatography (RP-LC) method was validated for the assessment of recombinant human interleukin-11 (rhIL-11), based on the ICH guidelines. The method was carried out on a Jupiter C(4) column (250 mm × 4.6 mm i.d.), maintained at 25°C. The mobile phase A consisted of 0.1% trifluoroacetic acid (TFA) and the mobile phase B was acetonitrile with 0.1% TFA, run at a flow rate of 1 mL/min, and using a photodiode array (PDA) detection at 214 nm. Separation was obtained with a retention time of 27.6 min, and was linear over the concentration range of 1-200 µg/mL (r(2) = 0.9995). Specificity was established in degradation studies, which also showed that there was no interference of the excipients. The accuracy was 100.22% with bias lower than 1.25%. Moreover, the in vitro cytotoxicity test of the degraded products showed non-significant differences (p > 0.05). The method was applied to the assessment of rhIL-11 and related proteins in biopharmaceutical dosage forms, and the results were correlated to those of a bioassay.

  8. A METHOD TO SEARCH FOR CORRELATIONS OF ULTRA-HIGH ENERGY COSMIC-RAY MASSES WITH THE LARGE-SCALE STRUCTURES IN THE LOCAL GALAXY DENSITY FIELD

    Energy Technology Data Exchange (ETDEWEB)

    Ivanov, A. A., E-mail: ivanov@ikfia.ysn.ru [Shafer Institute for Cosmophysical Research and Aeronomy, 31 Lenin Avenue, Yakutsk 677980 (Russian Federation)

    2013-02-15

    One of the main goals of investigations using present and future giant extensive air shower (EAS) arrays is the mass composition of ultra-high energy cosmic rays (UHECRs). A new approach to the problem is presented, combining the analysis of arrival directions with the statistical test of the paired EAS samples. One of the ideas of the method is to search for possible correlations between UHECR masses and their separate sources; for instance, if there are two sources in different areas of the celestial sphere injecting different nuclei, but the fluxes are comparable so that arrival directions are isotropic, then the aim is to reveal a difference in the mass composition of cosmic-ray fluxes. The method is based on a non-parametric statistical test-the Wilcoxon signed-rank routine-which does not depend on the populations fitting any parameterized distributions. Two particular algorithms are proposed: first, using measurements of the depth of the EAS maximum position in the atmosphere; and second, relying on the age variance of air showers initiated by different primary particles. The formulated method is applied to the Yakutsk array data, in order to demonstrate the possibility of searching for a difference in average mass composition between the two UHECR sets, arriving particularly from the supergalactic plane and a complementary region.

  9. Reliability of thermal conductivity measurement of liquids by using transient hot-wire, photon-correlation spectroscopy and the laser flash method

    Science.gov (United States)

    Kwon, Suyong; Lee, Joohyun; Kim, Dae Ho

    2016-05-01

    Measuring the thermal conductivity of liquids is important, but not easy, because of the complexity of and the natural convection in liquids, and reliable thermal conductivity measurements in liquids under various sample conditions is essential for data accuracy. We have introduced and developed a validation chain for measuring the thermal conductivity of liquids by using three different experimental methods: the transient hot-wire (THW), the photon correlation spectroscopy (PCS) and the laser flash (LF) methods in the temperature range from -30 to 90 °C. We checked the performance of the validation chain developed in this study by measuring the thermal conductivity of liquid toluene. We found good agreement between the thermal conductivity data obtained by using the THW, PCS and LF methods. To demonstrate the use of this validation chain for measurements of thermophysical properties in liquids, we also showed its use in measuring the specific heat of a volatile liquid, toluene which can be extracted from thermal conductivity, thermal diffusivity, and density measurements without any effects of volatilization.

  10. Determining the Correlation Between Three and Seven Day Records of Fluids Consumption to Determine an Appropriate Method for Estimating the Amount and Type of Fluids Intake in Adults

    Directory of Open Access Journals (Sweden)

    Karandish

    2016-09-01

    Full Text Available Background Different methods are used for adequate fluid intake assessment, while there is no standard method for adequate fluid intake assessment. Objectives The current pilot study aimed to evaluate the amount, type and frequency of fluids consumption to determine the correlation between three- and seven-day records. Methods This pilot cross-sectional study was done on 30 adult subjects in Ahvaz, Iran during year 2014. Demographic data were collected via a questionnaire and fluids consumption was assessed with a seven days records questionnaire. For data analyses the SPSS 16 software was used. Results Results of this cross-sectional study showed that the average total daily fluids consumption was 1.6 liter. Total fluids consumption for each subject on average in three and seven days was 4.5 and 11 liter, respectively. Water was the major fluid, which the participants consumed and tea was the second item. Total amount and frequency of fluids intake were not significantly different between three and seven-day records (P = 0.287, (P = 0.546. Conclusions This study showed that there was no significant difference between the record of seven and three days of fluids consumption in the participants and it is suggested that three-day records is useful in order to determine fluids intake.

  11. Stability-indicating capillary zone electrophoresis method for the assessment of recombinant human interleukin-11 and its correlation with reversed-phase liquid chromatography and biossay.

    Science.gov (United States)

    Souto, Ricardo Bizogne; Stamm, Fernanda Pavani; Schumacher, Jéssica Barbieri; Cardoso, Clovis Dervil Appratto; de Freitas, Guilherme Weber; Perobelli, Rafaela Ferreira; Dalmora, Sérgio Luiz

    2014-06-01

    A stability-indicating capillary zone electrophoresis (CZE) method was validated for the analysis of recombinant human interleukin-11(rhIL-11) using rupatadine fumarate, as internal standard (IS). A fused-silica capillary, (50 µm i.d.; effective length, 40 cm) was used at 25°C; the applied voltage was 20 kV. The background electrolyte solution consisted of 50 mmol L(-1) sodium dihydrogen phosphate solution at pH 3.0. Injections were performed using a pressure mode at 50 mbar for 45 s, with detection by photodiode array detector set at 196 nm. Specificity and stability-indicating capability were established in degradation studies, which also showed that there was no interference of the excipients. The method was linear over the concentration range of 1.0-300 µg mL(-1) (r(2)=0.9992) and the limit of detection (LOD) and limit of quantitation (LOQ) were 0.2 µg mL(-1) and 1.0 µg mL(-1), respectively. The accuracy was 100.4% with bias lower than 1.1%. Moreover, the in vitro cytotoxicity test of the degraded products showed significant differences (pmethod was applied for the content/potency assessment of rhIL-11 in biopharmaceutical formulations, and the results were correlated to those of a validated reversed-phase LC method (RP-LC) and an TF-1 cell culture assay, showing non-significant differences (p>0.05). In addition the CZE and RP-LC methods were applied for the analysis of rhIL-11 in human plasma. Therefore, the proposed alternative method can be applied to monitor stability, to assure the batch-to-batch consistency and quality of the bulk and finished biotechnology-derived medicine.

  12. High-accuracy 2D digital image correlation measurements using low-cost imaging lenses: implementation of a generalized compensation method

    Science.gov (United States)

    Pan, Bing; Yu, Liping; Wu, Dafang

    2014-02-01

    The ideal pinhole imaging model commonly assumed for an ordinary two-dimensional digital image correlation (2D-DIC) system is neither perfect nor stable because of the existence of small out-of-plane motion of the test sample surface that occurred after loading, small out-of-plane motion of the sensor target due to temperature variation of a camera and unavoidable geometric distortion of an imaging lens. In certain cases, these disadvantages can lead to significant errors in the measured displacements and strains. Although a high-quality bilateral telecentric lens has been strongly recommended to be used in the 2D-DIC system as an essential optical component to achieve high-accuracy measurement, it is not generally applicable due to its fixed field of view, limited depth of focus and high cost. To minimize the errors associated with the imperfectness and instability of a common 2D-DIC system using a low-cost imaging lens, a generalized compensation method using a non-deformable reference sample is proposed in this work. With the proposed method, the displacement of the reference sample rigidly attached behind the test sample is first measured using 2D-DIC, and then it is fitted using a parametric model. The fitted parametric model is then used to correct the displacements of the deformed sample to remove the influences of these unfavorable factors. The validity of the proposed compensation method is first verified using out-of-plane translation, out-of-plane rotation, in-plane translation tests and their combinations. Uniaxial tensile tests of an aluminum specimen were also performed to quantitatively examine the strain accuracy of the proposed compensation method. Experiments show that the proposed compensation method is an easy-to-implement yet effective technique for achieving high-accuracy deformation measurement using an ordinary 2D-DIC system.

  13. 基于相关匹配的QR码识别方法%QR code recognition method based on correlation match

    Institute of Scientific and Technical Information of China (English)

    熊用; 汪鲁才; 艾琼龙

    2011-01-01

    QR码图像识别是QR码应用中的关键技术.Hough变换、曲面拟合去背景、控制点变换等方法为QR码识别过程中图像预处理的基本方法,针对图像预处理后图像识别率低的缺点,提出了一种基于相关匹配法的QR码识别方法.基于曲面拟合的改进自适应阈值法分割图像.采用Hough变换和控制点变换方法校正图像的几何失真变形.利用模板对QR码进行相关匹配,对相干系数阈值处理得出取样网格.实验表明,本文算法能有效提高QR码识别效率和效果.%QR code recognition is the key technology in QR code application. Hough transformation, surface-fitting background removing and control point transformation are the essential methods of image preprocessing in QR code recognition. An improved QR code recognition method based on correlation match is proposed in this paper, which improves the low efficiency of the image recognition after image preprocessing. An improved adaptive threshold value method based on surface fitting is used to segment the QR code image. Hough transform and control point transformation methods are used to correct the geometric distortion deformation of the image. A template is used to carry out the match of the QR code image; and the coherent coefficient image is obtained easily. Then, a selected coherent coefficient threshold is processed and the sample grid image is obtained. Simulated results prove that the proposed method can greatly improve the QR code recognition efficiency and effect.

  14. Alternative methods for estimating common descriptors for QSAR studies of dyes and fluorescent probes using molecular modeling software. 2. Correlations between log P and the hydrophilic/lipophilic index, and new methods for estimating degrees of amphiphilicity.

    Science.gov (United States)

    Dapson, Richard W; Horobin, Richard W

    2013-11-01

    The log P descriptor, despite its usefulness, can be difficult to use, especially for researchers lacking skills in physical chemistry. Moreover this classic measure has been determined in numerous ways, which can result in inconsistant estimates of log P values, especially for relatively complex molecules such as fluorescent probes. Novel measures of hydrophilicity/lipophilicity (the Hydrophilic/Lipophilic Index, HLI) and amphiphilicity (hydrophilic/lipophilic indices for the head group and tail, HLIT and HLIHG, respectively) therefore have been devised. We compare these descriptors with measures based on log P, the standard method for quantitative structure activity relationships (QSAR) studies. HLI can be determined using widely available molecular modeling software, coupled with simple arithmetic calculations. It is based on partial atomic charges and is intended to be a stand-alone measure of hydrophilicity/lipophilicity. Given the wide application of log P, however, we investigated the correlation between HLI and log P using a test set of 56 fluorescent probes of widely different physicochemical character. Overall correlation was poor; however, correlation of HLI and log P for probes of narrowly specified charge types, i.e., non-ionic compounds, anions, conjugated cations, or zwitterions, was excellent. Values for probes with additional nonconjugated quaternary cations, however, were less well correlated. The newly devised HLI can be divided into domain-specific descriptors, HLIT and HLIHG in amphiphilic probes. Determinations of amphiphilicity, made independently by the authors using their respective methods, showed excellent agreement. Quantifying amphiphilicity from partial log P values of the head group (head group hydrophilicity; HGH) and tail (amphiphilicity index; AI) has proved useful for understanding fluorescent probe action. The same limitations of log P apply to HGH and AI, however. The novel descriptors, HLIT and HLIHG, offer analogous advantages

  15. Why do TD-DFT excitation energies of BODIPY/Aza-BODIPY families largely deviate from experiment? Answers from electron correlated and multireference methods.

    Science.gov (United States)

    Momeni, Mohammad R; Brown, Alex

    2015-06-09

    The vertical excitation energies of 17 boron-dipyrromethene (BODIPY) core structures with a variety of substituents and ring sizes are benchmarked using time-dependent density functional theory (TD-DFT) with nine different functionals combined with the cc-pVTZ basis set. When compared to experimental measurements, all functionals provide mean absolute errors (mean AEs) greater than 0.3 eV, larger than the 0.1-0.3 eV differences typically expected from TD-DFT. Due to the high linear correlation of TD-DFT results with experiment, most functionals can be used to predict excitation energies if corrected empirically. Using the CAM-B3LYP functional, 0-0 transition energies are determined, and while the absolute difference is improved (mean AE = 0.478 eV compared to 0.579 eV), the correlation diminishes substantially (R(2) = 0.961 to 0.862). Two very recently introduced charge transfer (CT) indices, q(CT) and d(CT), and electron density difference (EDD) plots demonstrate that CT does not play a significant role for most of the BODIPYs examined and, thus, cannot be the source of error in TD-DFT. To assess TD-DFT methods, vertical excitation energies are determined utilizing TD-HF, configuration interaction CIS and CIS(D), equation of motion EOM-CCSD, SAC-CI, and Laplace-transform based local coupled-cluster singles and approximate doubles LCC2* methods. Moreover, multireference CASSCF and CASPT2 vertical excitation energies were also obtained for all species (except CASPT2 was not feasible for the four largest systems). The SAC-CI/cc-pVDZ, LCC2*/cc-pVDZ, and CASPT2/cc-pVDZ approaches are shown to have the smallest mean AEs of 0.154, 0.109, and 0.100 eV, respectively; the utility of the LCC2* approach is demonstrated for eight extended BODIPYs and aza-BODIPYs. We found that the problems with TD-DFT arise from difficulties in dealing with the differential electron correlation (as assessed by comparing CCS, CC2, LR-CCSD, CCSDR(T), and CCSDR(3) vertical excitation energies for