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Sample records for cor triatriatum dexter

  1. Cor triatriatum dexter: A rare cause of childhood cyanosis

    Directory of Open Access Journals (Sweden)

    Ahmad Rustam bin Mohd Zainudin

    2012-01-01

    Full Text Available Cor triatriatum dexter is a rare congenital heart anomaly where the right atrium is divided into two chambers by a membrane. We report a boy who had persistent mild cyanosis and diagnosed to have cor triatriatum dexter with secundum atrial septal defect by transoesophageal echocardiography. Interestingly, he had persistent mild cyanosis despite insignificant obstruction to the right ventricular inflow and normal pulmonary artery pressure. The pathophysiology, approach to the diagnosis, and mode of treatment are also discussed.

  2. Cor triatriatum dexter: A rare cause of cyanosis during neonatal period.

    Science.gov (United States)

    Alghamdi, Mohammed Hussien

    2016-01-01

    Cor-triatriatum dexter is an extremely rare congenital heart defect in which there is complete persistence of the right valve of embryonic sinus venosus that results in partitioning of the right atrium into a smooth and trabeculated portion. The smooth portion receives venous blood from inferior vena cava, superior vena cava, and coronary sinus while the trabeculated portion contains the right atrial appendage and the opening of tricuspid valve. We report a 1-week-old child who presented with intermittent episodes of central cyanosis. Echocardiography, established, and bubble contrast study confirmed the diagnosis of an isolated cor-triatriatum dexter. The baby initially underwent an intervention by cardiac catheterization, which was unsuccessful in disrupting the membrane and re-direct the systemic venous flow to the right heart chambers. She subsequently had the cor-triatriatum dexter membrane resected via an uncomplicated open-heart surgery.

  3. Cor triatriatum dexter and atrial septal defect in a 43-year-old woman.

    Science.gov (United States)

    Vukovic, Petar M; Kosevic, Dragana; Milicic, Miroslav; Jovovic, Ljiljana; Stojanovic, Ivan; Micovic, Slobodan

    2014-08-01

    Cor triatriatum dexter is a rare congenital heart anomaly in which a membrane divides the right atrium into 2 chambers. We report the case of a 43-year-old woman who had cor triatriatum dexter and a large atrial septal defect. During attempted percutaneous closure, the balloon disrupted the membrane and revealed that the defect had no inferior rim, precluding secure placement of an Amplatzer Septal Occluder. Surgical treatment subsequently proved to be successful. In patients with an incomplete membrane and a septal defect with well-defined rims, percutaneous treatment can be the first choice. In patients who have cor triatriatum dexter and unfavorable anatomic features or concomitant complex heart anomalies, open-heart surgery remains the gold standard for treatment.

  4. Cor triatriatum dexter in a dog

    International Nuclear Information System (INIS)

    Brayley, K.A.; Lunney, J.; Ettinger, S.J.

    1994-01-01

    A six-year-old, spayed, female German shepherd dog cross was evaluated for distention of the caudal vena cava. Differential diagnoses included right heart defects and Budd-Chiari type lesions. Radiography, echocardiography, cardiac catheterization, and angiography demonstrated cor triatriatum dexter. This rare congenital anomaly of the right atrium has been described previously in veterinary patients with a right heart failure syndrome. This dog was asymptomatic, therefore, surgical correction was not undertaken

  5. Cor triatriatum dexter associated with atrial septal defect: Management in a complex clinical case.

    Science.gov (United States)

    Sozzi, Fabiola B; Montanaro, Claudia; Bacà, Laura; Viani, Giacomo M; Zilocchi, Massimo; Canetta, Ciro; Meazza, Roberto; Pavone, Laura; Lombardi, Federico

    2017-11-01

    The coexistence of an atrial septal defect and a prominent eustachian valve is a rare congenital anomaly, rarely reported in literature. Differentiation between a giant eustachian valve and cor triatriatum dexter can be difficult. A case of a large atrial septal defect associated with cor triatriatum dexter diagnosed by echocardiography in an asymptomatic woman is reported. A watchful waiting strategy was adopted. © 2017, Wiley Periodicals, Inc.

  6. Fetal cor triatriatum dexter: a report of two cases associated with nuchal edema in early second trimester

    DEFF Research Database (Denmark)

    Maroun, L.L.; Graem, N.; Skibsted, L.

    2008-01-01

    Two early-2nd-trimester fetuses were aborted as a result of nuchal edema and suspected severe heart malformation. At autopsy one fetus demonstrated nuchal edema, mild hydronephrosis, and cor triatriatum dexter associated with ventricular septal defect and tubular hypoplasia of the aortic arch....... The other fetus demonstrated severe nuchal edema, and cor triatriatum dexter was the only malformation. Cor triatriatum dexter is a rare cardiac malformation characterized by division of the right atrium into 2 compartments by a usually fenestrated membrane representing remnants of the right valve...

  7. Cor triatriatum dexter, atrial septal defects, and pulmonary stenosis-a rare association.

    Science.gov (United States)

    Simsek, Ziya; Koza, Yavuzer; Tas, Hakan

    2014-04-01

    Cor triatriatum dexter (CTD) is an extremely rare congenital anomaly in which the right atrium is divided into 2 chambers by a membrane. The estimated incidence of cor triatriatum has been reported as 0.1% of congenital cardiac malformations. The septation of the right atrium in the setting of CTD is the result of failed resorption of the right valve of the sinus venosus. This results in anterolateral and posteromedial portions of the divided right atrium. CTD can be diagnosed at any age, especially if it is incidentally discovered. © 2014, Wiley Periodicals, Inc.

  8. Transthoracic ultrasound guided balloon dilation of cor triatriatum dexter in 2 Rottweiler puppies.

    Science.gov (United States)

    Birettoni, F; Caivano, D; Bufalari, A; Giorgi, M E; Miglio, A; Paradies, P; Porciello, F

    2016-12-01

    Balloon dilation was performed in two Rottweiler puppies with cor triatriatum dexter and clinical signs of ascites using transthoracic echocardiographic guidance. The dogs were positioned on a standard echocardiography table in right lateral recumbency, and guide wires and balloon catheters were imaged by echocardiographic views optimized to allow visualization of the defect. The procedures were performed successfully without complications and clinical signs were resolved completely in both cases. Guide wires and balloon catheters appeared hyperechoic on transthoracic echocardiography image and could be clearly monitored and guided in real-time. These two cases demonstrate that it is possible to perform balloon catheter dilation of cor triatriatum dexter under transthoracic guidance alone. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Imperforated cor triatriatum dexter in a dog with concurrent caudal vena cava wall mineralization

    NARCIS (Netherlands)

    Dobak, Tetyda Paulina; Starrak, Gregory; Linn, Kathleen; Snead, Elisabeth Christine Roberston

    2017-01-01

    BACKGROUND: Cor triatriatum dexter (CTD) is a rare congenital cardiac malformation with various manifestations and has been sporadically described in dogs. Clinically the dogs present with nonspecific signs of right heart failure or Budd-Chiari-like syndrome. Other associated concurrent

  10. Unique sail-like structure of cor triatriatum dexter in three-dimensional echocardiogram.

    Science.gov (United States)

    Low, Ting Ting; Uy, Celia Catherine C; Wong, Raymond Ching Chiew

    2014-08-01

    Cor triatriatum dexter (CTD) is an extremely rare congenital condition arising from the persistence of the right valve of the sinus venosus. It divides the right atrium (RA) into 2 separate chambers. We report a case of a 50-year-old man who had an incidental finding of CTD on transesophageal echocardiogram. An incomplete membrane of the RA was seen, and three-dimensional echocardiogram delineated the structure clearly as a triangular sail-like structure with multiple orifices and a fenestration. © 2013, Wiley Periodicals, Inc.

  11. Cor triatriatum dexter, a very rare congenital anomaly presented in a complex pathological context – case presentation

    Directory of Open Access Journals (Sweden)

    Gozar Liliana

    2014-08-01

    Full Text Available Background Cor triatriatum dexter is an extremely rare congenital anomaly, and in most cases, without hemodynamic significance. Congenital cytomegalovirus infection is the most common viral infection, the majority of infected infants being asymptomatic and only 5-15% being symptomatic in the neonatal period.

  12. Stent placement for palliation of cor triatriatum dexter in a dog with suspected patent foramen ovale.

    Science.gov (United States)

    Barncord, Kristin; Stauthammer, Christopher; Moen, Sean L; Hanson, Melissa; Gruenstein, Daniel H

    2016-03-01

    An 11 month old spayed, female dog presented with exercise intolerance and cyanosis upon exertion. Echocardiography revealed an imperforate cor triatriatum dexter with mild tricuspid valve dysplasia, an underfilled right ventricle and significant right to left shunting across a presumptive patent foramen ovale. Balloon dilation of the abnormal atrial membrane was initially successful in creating a communication between the right atrial chambers, but stenosis of the original perforation and persistent clinical signs prompted a second intervention. A balloon expandable biliary stent was placed across the abnormal partition, improving caudal venous return to the right ventricle and reducing the right to left shunt. Three months after stent placement, resting oxygen saturation had normalized. Six months after stent placement, exercise tolerance had improved and exertional cyanosis had resolved. Long term follow up will be necessary to assess for remodeling of the right ventricle with improved venous return. Stent placement can be considered as a palliative treatment option for cor triatriatum dexter, especially for stenosis post-balloon dilation. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Complete A-V block: incidental or a part of cor triatriatum dexter.

    Science.gov (United States)

    Guler, Y; Akgun, T; Toprak, C; Guler, A; Esen, A M

    2014-05-01

    Cor triatriatum dexter (CTD) is an extremely rare cardiac anomaly in which the right atrium is divided into two distinct chambers by a membrane. The persistence of the right valve of sinus venosus results in a complete septation of the right atrium. This anomaly is frequently associated with other right-sided cardiac abnormalities. Its clinical manifestation and the need for intervention are determined by the number and the size of the fenestrations on the membrane, associated cardiac anomalies and arrhythmias. We describe a case of CTD in a patient with complete atrioventricular (A-V) block.

  14. Cyanosis and Stroke due to Functional Cor Triatriatum Dexter in a Neonate.

    Science.gov (United States)

    León, Rachel L; Zaban, Nicholas B; Schamberger, Marcus S; Ho, Chang Y; Mietzsch, Ulrike

    2018-01-01

    Small remnants of the right valve of the sinus venosus are commonly found in adults, but the incidence and risk associated with these embryonic remnants in neonates are not well studied. The following report describes a cyanotic neonate with a large Eustachian valve remnant creating a functional cor triatriatum dexter who was initially diagnosed with persistent pulmonary hypertension of the newborn. The cyanosis in this infant improved over the first postnatal week with conservative management, but she suffered multifocal subcortical stroke, likely related to her intracardiac shunt. The clinical presentation and questions regarding long-term management of this rare diagnosis are explored. © 2018 S. Karger AG, Basel.

  15. Cor triatriatum sinister e hipertensão arterial pulmonar secundária em cão

    Directory of Open Access Journals (Sweden)

    T. Champion

    2014-02-01

    Full Text Available This paper describes the occurrence of cor triatriatum sinister, a rare cardiac malformation in dogs, associated with pulmonary edema and pulmonary hypertension in a 5-year-old Poodle female with history of acute dyspnea and cyanosis. The animal presented acute respiratory failure, heart failure with low cardiac output, progressing to acute tubular necrosis and death. The diagnosis was made posmortem due to the clinical instability of the dog. This malformation was diagnosed by the subdivision of the left atrium into two compartments separated by an abnormal fibromuscular membrane, absence of structural abnormalities of the mitral valve and thickening of pulmonary artery tunica media associated with renal tubular degeneration. The occurrence of cor triatriatum in dogs is most common in the right atrium, defined as cor triatriatum dexter. Additionally, pulmonary arterial hypertension associated with this malformation is described only in humans with this heart defect.

  16. Anaesthetic management of a child with "cor-triatriatum" and multiple ventricular septal defects - A rare congenital anomaly

    Directory of Open Access Journals (Sweden)

    Sriram Sabade

    2010-01-01

    Full Text Available Cor-triatriatum is a rare congenital cardiac anomaly. It accounts for 0.1% of congenital heart diseases. Its association with multiple ventricular septal defects (VSD is even rarer. A five-month-old baby was admitted with respiratory distress and failure to thrive. Clinical examination revealed diastolic murmur over mitral area. Chest X-ray showed cardiomegaly. Haematological and biochemical investigations were within normal limits. Electrocardiogram showed left atrial enlargement. 2D echo showed double-chambered left atrium (cor-triatriatum, atrial septal defect (ASD and muscular VSD with moderate pulmonary arterial hypertension. The child was treated with 100% oxygen, diuretics and digoxin and was stabilized medically. We used balanced anaesthetic technique using oxygen, air, isoflurane, fentanyl, midazolam and vecuronium. Patient was operated under cardiopulmonary bypass (CPB with moderate hypothermia. Through right atriotomy abnormal membrane in the left atrium was excised to make one chamber. VSD were closed with Dacron patches and ASD was closed with autologous pericardial patch. Patient tolerated the whole procedure well and was ventilated electively for 12h in the intensive care unit. He was discharged on the 10 th postoperative day.

  17. Mutations in HYAL2, Encoding Hyaluronidase 2, Cause a Syndrome of Orofacial Clefting and Cor Triatriatum Sinister in Humans and Mice.

    Directory of Open Access Journals (Sweden)

    Martina M A Muggenthaler

    2017-01-01

    Full Text Available Orofacial clefting is amongst the most common of birth defects, with both genetic and environmental components. Although numerous studies have been undertaken to investigate the complexities of the genetic etiology of this heterogeneous condition, this factor remains incompletely understood. Here, we describe mutations in the HYAL2 gene as a cause of syndromic orofacial clefting. HYAL2, encoding hyaluronidase 2, degrades extracellular hyaluronan, a critical component of the developing heart and palatal shelf matrix. Transfection assays demonstrated that the gene mutations destabilize the molecule, dramatically reducing HYAL2 protein levels. Consistent with the clinical presentation in affected individuals, investigations of Hyal2-/- mice revealed craniofacial abnormalities, including submucosal cleft palate. In addition, cor triatriatum sinister and hearing loss, identified in a proportion of Hyal2-/- mice, were also found as incompletely penetrant features in affected humans. Taken together our findings identify a new genetic cause of orofacial clefting in humans and mice, and define the first molecular cause of human cor triatriatum sinister, illustrating the fundamental importance of HYAL2 and hyaluronan turnover for normal human and mouse development.

  18. [Cor triatriatum. Anatomical forms and surgical treatment of 6 consecutive cases].

    Science.gov (United States)

    Bloch, G; Heurtematte, Y; Menu, P; Mesnildrey, P; Casasoprana, A; Magnier, S; Tamari, W; Seurat, M C; Aubry, P; Vernant, P

    1988-01-01

    Six cases of cor triatriatum documented and operated on at Henri-Mondor hospital between 1980 and 1984 are reported. Ages at the time of surgery ranged from 8 months to 57 years. Four of the 6 patients presented with pulmonary hypertension. Anatomic types consisted of 4 diaphragmatic types and 2 more complex malformations. Associated lesions were present in all but one patients. They consisted mostly of interatrial defects (depending on their position with regard to the intra-atrial membrane, they play a determinant role in the symptomatology) and of a left superior vena cava (which might play a role in the embryogenesis of the malformation). Except for one early postoperative death, results of surgery were excellent for all patients, with a mean follow-up of 5 years. This series, compared with the literature, allows precising the embryologic and anatomic aspects of the malformation and the surgical techniques in complex types.

  19. Cor triatriatum izquierdo diagnosticado tardíamente. Reporte de caso

    Directory of Open Access Journals (Sweden)

    Francisco J. Vázquez-Roque

    2016-09-01

    Full Text Available El Cor Triatriatum izquierdo es una anomalía congénita cardiaca rara. Es infrecuente que estos pacientes sobrepasen la edad de 40 años sin su corrección quirúrgica. El objetivo de este artículo fue el de presentar un paciente de 43 años que fue intervenido quirúrgicamente a la edad de 5 años para el cierre de una comunicación interauricular y donde el diagnóstico de esta entidad no se realizó. Un mes antes del ingreso comienza con palpitaciones y disnea a los moderados esfuerzos. Con la ecografía transesofágica se hace el diagnóstico de esta anomalía, la cual se asociaba a una insuficiencia mitral y fibrilación auricular. Se procedió a la resección de la membrana fibromuscular y la reparación de dos hendiduras congénitas en el borde del velo anterior de la válvula mitral con buenos resultados. Un año después el paciente se encuentra asintomático y en la ecocardiografía transtoráxica se muestra una aurícula izquierda unicameral con una regurgitación mitral trivial.

  20. Morphological dilemma: Anomalous pulmonary venous confluence or cor triatriatum—does it matter?

    Directory of Open Access Journals (Sweden)

    Nagarajan Muthialu

    2018-01-01

    Full Text Available Cardiac variant of total anomalous pulmonary venous return is a rare entity, whereby all the pulmonary veins drain directly to the right atrium or coronary sinus. The effective left heart blood flow channels through a small stretched patent foramen ovale and can often be confused with a variant of cor triatriatum. Cor triatriatum is a rare congenital cardiac anomaly where pulmonary veins drain to a persistent chamber above the left atrium with a membrane separating these two. There persists either a small aperture directly from the true to the accessory left atrium or none at all. Where there is no such aperture, it is often physiologically akin to the cardiac variant of total anomalous pulmonary venous return described above. Such morphological differentiation is often challenging in a clinical situation, but the effective treatment remains the same. It involves removal of the common wall between the two chambers and baffling the pulmonary veins effectively to the left atrium. We describe such a case where the pulmonary venous return is to the right atrium, managed recently in our centre, and discuss the morphological differences between these two.

  1. Incidental discovery of an unusual right atrial membrane in an adult patient

    Directory of Open Access Journals (Sweden)

    Nasrin N Aldawoodi

    2012-01-01

    Full Text Available We describe presence of an unusual right atrial membrane in a 30-year old female with end stage renal disease, hypertension and peripheral vascular disease. The patient was scheduled for midline sternotomy and pericardiotomy and removal of a migrated vascular stent in the right pulmonary artery. An intraoperative transesophageal echocardiogram (TEE revealed an unusual membranous structure with fenestrations that stretched across the right atrium with attachments superiorly at the free wall and inferiorly at the inter-atrial septum. There was no evidence of flow obstruction across the tricuspid valve. Some of the considerations for the likely diagnosis of this structure were a prominent Eustachian valve, persistent Chiari network, aneurysmal inter-atrial septum, an inter-atrial septal cyst or Cor triatriatum dexter (CTD.

  2. Dexter energy transfer pathways.

    Science.gov (United States)

    Skourtis, Spiros S; Liu, Chaoren; Antoniou, Panayiotis; Virshup, Aaron M; Beratan, David N

    2016-07-19

    Energy transfer with an associated spin change of the donor and acceptor, Dexter energy transfer, is critically important in solar energy harvesting assemblies, damage protection schemes of photobiology, and organometallic opto-electronic materials. Dexter transfer between chemically linked donors and acceptors is bridge mediated, presenting an enticing analogy with bridge-mediated electron and hole transfer. However, Dexter coupling pathways must convey both an electron and a hole from donor to acceptor, and this adds considerable richness to the mediation process. We dissect the bridge-mediated Dexter coupling mechanisms and formulate a theory for triplet energy transfer coupling pathways. Virtual donor-acceptor charge-transfer exciton intermediates dominate at shorter distances or higher tunneling energy gaps, whereas virtual intermediates with an electron and a hole both on the bridge (virtual bridge excitons) dominate for longer distances or lower energy gaps. The effects of virtual bridge excitons were neglected in earlier treatments. The two-particle pathway framework developed here shows how Dexter energy-transfer rates depend on donor, bridge, and acceptor energetics, as well as on orbital symmetry and quantum interference among pathways.

  3. Designing Dexter-based cooperative hypermedia systems

    DEFF Research Database (Denmark)

    Grønbæk, Kaj; Madsen, Ole Lehrmann; Sloth, Lennard

    1993-01-01

    This paper discusses issues for the design of a Dexter-based cooperative hypermedia architecture and a specific system, DeVise Hypermedia (DHM), developed from this architecture. The Dexter Hypertext Reference Model [Hala90] was used as basis for designing the architecture. The Dexter model...... provides a general and solid foundation for designing a general hypermedia architecture. It introduces central concepts and proposes a layering of the architecture. However, to handle cooperative work aspects, such as sharing material and cooperative authoring, we have to go beyond the Dexter model...... concepts. To deal with such aspects we have extended our implementation of the Dexter concepts with support for long-term transactions, locking and event notification as called for by Halasz [Hala88]. The result is a platform independent architecture for developing cooperative hypermedia systems...

  4. To Dexter - A Tribute from Aarhus

    DEFF Research Database (Denmark)

    Schmidt, Erik Meineche; Skyum, Sven; Nielsen, Mogens

    2012-01-01

    At Aarhus University, we consider Dexter to be one of our oldest and best friends and colleagues. Dexter has visited our Department of Computer Science as a guest professor twice, first in 1981–1982 and again, exactly 10 years later, in 1991–1992. Both visits were immensely successful and laid...... the ground for continued cooperation during the following years. Dexter made numerous shorter visits to the department, and he served with great enthusiasm and competence on the advisory board for BRICS (Basic Research in Computer Science) Research Center and international PhD-School. BRICS covered both...... “Track A and B” activities (Algorithmics and Semantics), and as such Dexter was the ideal adviser. Looking back, we pay tribute to Dexter for his many contributions to computer science in Aarhus over a period of more than thirty years....

  5. SERIAL TELEVISI DEXTER SEBAGAI ANAKRONISME DALAM SASTRA POPULER

    OpenAIRE

    Ida Rochani Adi

    2014-01-01

    In the popular literature context, this study aims to investigate: (1) how the formulation of the characterization of Dexter in the television serial Dexter violates the tradition of literary characterization, and (2) how the formula of moral values is dramatized through Dexter, who is a sociopath, psychopath, serial killer, and person without moral. The research object was the television serial Dexter, which ranks five in popularity in the world. The data were collected by documenting 84 epi...

  6. Intelligent computational control of multi-fingered dexterous robotic hand

    OpenAIRE

    Chen, Disi; Li, Gongfa; Jiang, Guozhang; Fang, Yinfeng; Ju, Zhaojie; Liu, Honghai

    2015-01-01

    We discuss the intelligent computational control theory and introduce the hardware structure of HIT/DLR II dexterous robotic hand, which is the typical dexterous robotic hand. We show that how DSP or FPGA controller can be used in the dexterous robotic hand. A popular intelligent dexterous robotic hand control system, which named Electromyography (EMG) control is investigated. We introduced some mathematical algorithms in EMG controlling, such as Gauss mixture model (GMM), artificial neural n...

  7. Manual Dexterity in Schizophrenia—A Neglected Clinical Marker?

    Directory of Open Access Journals (Sweden)

    Maxime Térémetz

    2017-07-01

    Full Text Available Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially affected and how they relate to clinical characteristics also remains unclear. We quantified the degree of dexterity in 35 stabilized patients with schizophrenia and in 20 age-matched control subjects using four visuomotor tasks: (i force tracking to quantify visuomotor precision, (ii sequential finger tapping to measure motor sequence recall, (iii single-finger tapping to assess temporal regularity, and (iv multi-finger tapping to measure independence of finger movements. Diverse clinical and neuropsychological tests were also applied. A patient subgroup (N = 15 participated in a 14-week cognitive remediation protocol and was assessed before and after remediation. Compared to control subjects, patients with schizophrenia showed greater error in force tracking, poorer recall of tapping sequences, decreased tapping regularity, and reduced degree of finger individuation. A composite performance measure discriminated patients from controls with sensitivity = 0.79 and specificity = 0.9. Aside from force-tracking error, no other dexterity components correlated with antipsychotic medication. In patients, some dexterity components correlated with neurological soft signs, Positive and Negative Syndrome Scale (PANSS, or neuropsychological scores. This suggests differential cognitive contributions to these components. Cognitive remediation lead to significant improvement in PANSS, tracking error, and sequence recall (without change in medication. These findings show that multiple aspects of sensorimotor control contribute to impaired manual dexterity in schizophrenia. Only visuomotor precision was related to antipsychotic medication. Good diagnostic accuracy and responsiveness to treatment suggest that manual

  8. Edwin Grant Dexter: an early researcher in human behavioral biometeorology

    Science.gov (United States)

    Stewart, Alan E.

    2015-06-01

    Edwin Grant Dexter (1868-1938) was one of the first researchers to study empirically the effects of specific weather conditions on human behavior. Dexter (1904) published his findings in a book, Weather influences. The author's purposes in this article were to (1) describe briefly Dexter's professional life and examine the historical contexts and motivations that led Dexter to conduct some of the first empirical behavioral biometeorological studies of the time, (2) describe the methods Dexter used to examine weather-behavior relationships and briefly characterize the results that he reported in Weather influences, and (3) provide a historical analysis of Dexter's work and assess its significance for human behavioral biometeorology. Dexter's Weather influences, while demonstrating an exemplary approach to weather, health, and behavior relationships, came at the end of a long era of such studies, as health, social, and meteorological sciences were turning to different paradigms to advance their fields. For these reasons, Dexter's approach and contributions may not have been fully recognized at the time and are, consequently, worthy of consideration by contemporary biometeorologists.

  9. Control System Design of the YWZ Multi-Fingered Dexterous Hand

    Directory of Open Access Journals (Sweden)

    Wenzhen Yang

    2012-07-01

    Full Text Available The manipulation abilities of a multi-fingered dexterous hand, such as motion in real-time, flexibility, grasp stability etc., are largely dependent on its control system. This paper developed a control system for the YWZ dexterous hand, which had five fingers and twenty degrees of freedom (DOFs. All of the finger joints of the YWZ dexterous handwere active joints driven by twenty micro-stepper motors respectively. The main contribution of this paper was that we were able to use stepper motor control to actuate the hand's fingers, thus, increasing the hands feasibility. Based the actuators of the YWZ dexterous hand, we firstly developed an integrated circuit board (ICB, which was the communication hardware between the personal computer (PC and the YWZ dexterous hand. The ICB included a centre controller, twenty driver chips, a USB port and other electrical parts. Then, a communication procedure between the PC and the ICB was developed to send the control commands to actuate the YWZ dexterous hand. Experiment results showed that under this control system, the motion of the YWZ dexterous hand was real-time; both the motion accuracy and the motion stability of the YWZ dexterous hand were reliable. Compared with other types of actuators related to dexterous hands, such as pneumatic servo cylinder, DC servo motor, shape memory alloy etc., experiment results verified that the stepper motors as actuators for the dexterous handswere effective, economical, controllable and stable.

  10. SERIAL TELEVISI DEXTER SEBAGAI ANAKRONISME DALAM SASTRA POPULER

    Directory of Open Access Journals (Sweden)

    Ida Rochani Adi

    2014-06-01

    Full Text Available In the popular literature context, this study aims to investigate: (1 how the formulation of the characterization of Dexter in the television serial Dexter violates the tradition of literary characterization, and (2 how the formula of moral values is dramatized through Dexter, who is a sociopath, psychopath, serial killer, and person without moral. The research object was the television serial Dexter, which ranks five in popularity in the world. The data were collected by documenting 84 episodes of the serial having been broadcast since 2006. They were analyzed by means of content analysis and qualitative descriptive techniques. Based on the findings, the conclusions are as follows. First, there is a violation or anachronism of characterization through the main character in the serial. Second, the dramatized moral values still contain conventional values although they are in different forms.

  11. Businnes Model of Cors-Tr Tusaga-Aktif

    Science.gov (United States)

    Bakici, S.; Erkek, B.; İlbey, A.; Kulaksiz, E.

    2017-11-01

    CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network - Active)), serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  12. BUSINNES MODEL OF CORS-TR (TUSAGA-AKTIF

    Directory of Open Access Journals (Sweden)

    S. Bakici

    2017-11-01

    Full Text Available CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network – Active, serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  13. Cognitive object recognition system (CORS)

    Science.gov (United States)

    Raju, Chaitanya; Varadarajan, Karthik Mahesh; Krishnamurthi, Niyant; Xu, Shuli; Biederman, Irving; Kelley, Troy

    2010-04-01

    We have developed a framework, Cognitive Object Recognition System (CORS), inspired by current neurocomputational models and psychophysical research in which multiple recognition algorithms (shape based geometric primitives, 'geons,' and non-geometric feature-based algorithms) are integrated to provide a comprehensive solution to object recognition and landmarking. Objects are defined as a combination of geons, corresponding to their simple parts, and the relations among the parts. However, those objects that are not easily decomposable into geons, such as bushes and trees, are recognized by CORS using "feature-based" algorithms. The unique interaction between these algorithms is a novel approach that combines the effectiveness of both algorithms and takes us closer to a generalized approach to object recognition. CORS allows recognition of objects through a larger range of poses using geometric primitives and performs well under heavy occlusion - about 35% of object surface is sufficient. Furthermore, geon composition of an object allows image understanding and reasoning even with novel objects. With reliable landmarking capability, the system improves vision-based robot navigation in GPS-denied environments. Feasibility of the CORS system was demonstrated with real stereo images captured from a Pioneer robot. The system can currently identify doors, door handles, staircases, trashcans and other relevant landmarks in the indoor environment.

  14. Comparison of four variants of a major allergen in hazelnut (Corylus avellana) Cor a 1.04 with the major hazel pollen allergen Cor a 1.01

    DEFF Research Database (Denmark)

    Lüttkopf, D; Müller, U; Skov, P S

    2002-01-01

    of the recombinant variants: Cor a 1.0401>Cor a 1.0402 and 03>Cor a 1.0404 (the proline variant). Similar results for Cor a 1.0402 and 03 suggest a minor influence in IgE binding of cysteine in position 4, whereas proline in position 99 appears to be responsible for the decrease in IgE reactivity in Cor a 1...

  15. Impaired Finger Dexterity in Parkinson's Disease Is Associated with Praxis Function

    Science.gov (United States)

    Vanbellingen, T.; Kersten, B.; Bellion, M.; Temperli, P.; Baronti, F.; Muri, R.; Bohlhalter, S.

    2011-01-01

    A controversial concept suggests that impaired finger dexterity in Parkinson's disease may be related to limb kinetic apraxia that is not explained by elemental motor deficits such as bradykinesia. To explore the nature of dexterous difficulties, the aim of the present study was to assess the relationship of finger dexterity with ideomotor praxis…

  16. Intercomparison of the LASCO-C2, SECCHI-COR1, SECCHI-COR2, and Mk4 Coronagraphs

    Science.gov (United States)

    Frazin, Richard A.; Vasquez, Alberto M.; Thompson, William T.; Hewett, Russell J.; Lamy, Philippe; Llebaria, Antoine; Vourlidas, Angelos; Burkepile, Joan

    2012-01-01

    In order to assess the reliability and consistency of white-light coronagraph measurements, we report on quantitative comparisons between polarized brightness [pB] and total brightness [B] images taken by the following white-light coronagraphs: LASCO-C2 on SOHO, SECCHI-COR1 and -COR2 on STEREO, and the ground-based MLSO-Mk4. The data for this comparison were taken on 16 April 2007, when both STEREO spacecraft were within 3.1 deg. of Earth’s heliographic longitude, affording essentially the same view of the Sun for all of the instruments. Due to the difficulties of estimating stray-light backgrounds in COR1 and COR2, only Mk4 and C2 produce reliable coronal-hole values (but not at overlapping heights), and these cannot be validated without rocket flights or ground-based eclipse measurements. Generally, the agreement between all of the instruments’ pB values is within the uncertainties in bright streamer structures, implying that measurements of bright CMEs also should be trustworthy. Dominant sources of uncertainty and stray light are discussed, as is the design of future coronagraphs from the perspective of the experiences with these instruments.

  17. Sensing human hand motions for controlling dexterous robots

    Science.gov (United States)

    Marcus, Beth A.; Churchill, Philip J.; Little, Arthur D.

    1988-01-01

    The Dexterous Hand Master (DHM) system is designed to control dexterous robot hands such as the UTAH/MIT and Stanford/JPL hands. It is the first commercially available device which makes it possible to accurately and confortably track the complex motion of the human finger joints. The DHM is adaptable to a wide variety of human hand sizes and shapes, throughout their full range of motion.

  18. Comparing the level of dexterity offered by latex and nitrile SafeSkin gloves.

    Science.gov (United States)

    Sawyer, Jo; Bennett, Allan

    2006-04-01

    An increase in the occurrence of latex allergy has been concurrent with the increasing use of latex gloves by laboratory and healthcare workers. In recent years nitrile gloves have been used to replace latex gloves to prevent latex allergy. Nitrile gloves offer a comparable level of protection against chemical and biological agents and are more puncture resistant. However, if manual dexterity is compromised by nitrile gloves to a greater degree than latex then this may increase the risk of sharps injuries. The Purdue pegboard test, which measures both gross and fine finger dexterity, was used to test the dexterity levels of two glove types used at HPA CEPR; Kimberly-Clark SafeSkin nitrile and latex laboratory gloves. There was a statistically significant 8.6% increase in fine finger dexterity provided by latex compared with nitrile SafeSkin laboratory gloves but no difference in gross dexterity between the glove types. There was no significant relationship between glove dexterity and age or gender. The selection of glove size was influenced by the digit length of participants. Moreover, those with longer, thinner fingers appeared to have an advantage when using nitrile SafeSkin gloves. The level of dexterity provided by latex and nitrile SafeSkin gloves for tasks on a gross dexterity level are comparable and health workers will benefit from the non-allergenic properties of nitrile. For tasks requiring fine finger dexterity nitrile SafeSkin gloves may impede dexterity. Despite this, the degree of restriction appears to have a negligible impact on safety in this study when compared with the risk of latex sensitization and subsequent allergy. In addition to glove material, working practices must also take into account glove size, fit, grip and thickness, as these factors can all influence dexterity.

  19. Manual dexterity aptitude testing: a soap carving study.

    Science.gov (United States)

    Tang, Christopher G; Hilsinger, Raymond L; Cruz, Raul M; Schloegel, Luke J; Byl, Fred M; Rasgon, Barry M

    2014-03-01

    Currently there are few validated metrics for predicting surgical skill among otolaryngology residency applicants. To determine whether manual dexterity aptitude testing in the form of soap carving during otolaryngology residency interviews at Kaiser Permanente Medical Center Oakland predicts surgical skill at the time of graduation from otolaryngology residency programs. This study was conducted to determine how applicants with the best and worst soap carvings compared at the time of graduation with respect to various metrics including visuospatial ability and manual dexterity. Over the last 25 years, applicants to the residency program at Kaiser Permanente Oakland were required to carve soap during their residency interview. The 3 best and 3 worst soap carvings from 1990 through 2006 were determined. Of the individuals who carved those soaps, 62 qualified for the study and matriculated into otolaryngology residency programs. Surveys were sent to the 62 individuals' residency programs to evaluate those individuals on a 5-point Likert scale in various categories as well as to rank those individuals as being in the top 50% or bottom 50% of their graduating class. All else being equal, we hypothesized that applicants who had the manual dexterity and visuospatial skills to accurately carve a bar of soap would more likely possess the skills necessary to become a good surgeon. There was no difference between individuals with the best soap carvings and those with the worst soap carvings in all categories: cognitive knowledge, visuospatial ability, manual dexterity, decision making, and overall score (P > .10 for all categories). There was a 95% response rate, with 35 of 37 residency programs responding and 59 of 62 surveys returned. Manual dexterity aptitude testing in the form of soap carving does not appear to correlate with surgical skill at the time of graduation. Further studies need to be conducted to determine the role of manual dexterity and visuospatial

  20. Dexter: Data Extractor for scanned graphs

    Science.gov (United States)

    Demleitner, Markus

    2011-12-01

    The NASA Astrophysics Data System (ADS) now holds 1.3 million scanned pages, containing numerous plots and figures for which the original data sets are lost or inaccessible. The availability of scans of the figures can significantly ease the regeneration of the data sets. For this purpose, the ADS has developed Dexter, a Java applet that supports the user in this process. Dexter's basic functionality is to let the user manually digitize a plot by marking points and defining the coordinate transformation from the logical to the physical coordinate system. Advanced features include automatic identification of axes, tracing lines and finding points matching a template.

  1. Knotworking In An Interior Décor Process

    DEFF Research Database (Denmark)

    Rasmussen, Mai; Jensen, Rasmus Lund; Fisker, Anna Marie

    2016-01-01

    These days, new buildings are being built at Aalborg University in Denmark, why interior décor processes are initiated. Planning the interior décor of Aalborg University is centralized at the Shared Service Center, where internal architects furnish the spaces and buy the selected furniture withou...

  2. Design issues for a Dexter-based hypermedia system

    DEFF Research Database (Denmark)

    Grønbæk, Kaj; Trigg, Randall H.

    1992-01-01

    This paper discusses experiences and lessons learned from the design of an openhypermedia system, one that integrates applications and data not "owned" bythe hypermedia. The Dexter Hypertext Reference Model [8] was used as thebasis for the design. Though our experiences were generally positive, we...... foundthe model constraining in certain ways and underdeveloped in others. Forinstance, Dexter argues against dangling links, but we found several situationswhere permitting and supporting...

  3. Travelling with Dexter Kozen

    NARCIS (Netherlands)

    van Emde Boas, P.; Constable, R.L.; Silva, A.

    2012-01-01

    Aside from our shared interest in particular areas of Theoretical Computer Science, the experience I share with Dexter Kozen originates from the fact that we both belong to the not too large group of Theoreticiancs who during the late 1970-ies and early 1980-ies frequently crossed the Iron Curtain

  4. Effectiveness of Treatment of Idiopathic Scoliosis by SpineCor Dynamic Bracing with Special Physiotherapy Programme in SpineCor System.

    Science.gov (United States)

    Rożek, Karina; Potaczek, Tomasz; Zarzycka, Maja; Lipik, Ewa; Jasiewicz, Barbara

    2016-10-28

    The SpineCor dynamic brace for the treatment of idiopathic scoliosis is designed to maintain the correct position of the spine and a new movement strategy for 20 hours per day. The SpineCor exercise system intensifies and complements the brace treatment. This study evaluated the effectiveness of a comprehensive treatment of idiopathic scoliosis involving the SpineCor system. The study assessed a group of 40 patients (38 girls and 2 boys) with idiopathic scoliosis treated with the SpineCor brace. The average age at beginning of treatment was 13.1 yrs (10-15). Minimum treatment time was 18 months. 28 participants met the SRS criteria. Angles of the curve before and after bracing based on imaging studies were measured at the beginning and end of the treatment, analyzed and compared. Rehabilitation focused on teaching active corrective movement throughout the brace treatment. A control group was formed of 33 patients, including 21 meeting the SRS criteria, who used the SpineCor dynamic brace but did not participate in the associated exercise programme. Among patients from the exercise group who met the SRS criteria, 25% demonstrated reduced curve angles, 35.7% demonstrated curve progression and 39.3% showed stabilization (no change). Among patients meeting the SRS criteria from the control group, a decrease in curve angle was observed in 14.3% of the patients, curve progression in 57.1% and stabilization in 28.6%. 1. The addition of a dedicated physiotherapy programme to SpineCor dynamic bracing improves the chances of obtaining a positive outcome. 2. It is necessary to further analyse the course of the comprehensive treatment, also with regard to other types of braces and kinesiotherapy programmes.

  5. Wearing ambidextrous vinyl gloves does not impair manual dexterity.

    Science.gov (United States)

    Drabek, Tomas; Boucek, Charles D; Buffington, Charles W

    2013-01-01

    Universal precautions mandate that health care workers wear gloves to prevent the unintended spread of bloodborne pathogens. Gloves may affect manual dexterity, generally delaying task completion. Our previous study showed that wearing the wrong size latex surgical glove degraded manual dexterity. The use of non-sterile and non-latex gloves may limit certain risks and be more cost-effective. However, such gloves may produce different results. We hypothesized that ambidextrous vinyl examination gloves would degrade manual dexterity compared with bare hands. We studied 20 random subjects from a medical environment. Subjects performed a standard battery of Grooved Pegboard tasks while bare-handed, wearing ambidextrous non-sterile vinyl gloves that were their preferred size, a size too small, and a size too large. The order was randomized with a Latin Square design to minimize the effects of time, boredom, and fatigue on the subjects. Subjects were also invited to comment on the fit of different size gloves. Wearing vinyl gloves of both the preferred size and a size up or down failed to affect manual dexterity vs. bare hands on time to insert pegs, and pegs dropped during insertion or removal. In contrast, the time to remove pegs was reduced by wearing preferred size vinyl gloves compared with performing the task with bare hands (Pgloves that were too small caused significant hand discomfort. Vinyl gloves surprisingly do not degrade manual dexterity even when worn in ill-fitting sizes. Wearing a preferred size vinyl glove vs. bare hands may improve dexterity in selected tasks. Choosing a comfortable, large size seems the best strategy when the preferred size is unavailable. Thinner vinyl gloves may improve grip and may not degrade touch as much as latex surgical gloves and may thus represent a reasonable choice for selected tasks.

  6. Bio-inspired mechanical design of a tendon-driven dexterous prosthetic hand.

    Science.gov (United States)

    Controzzi, Marco; Cipriani, Christian; Jehenne, Beryl; Donati, Marco; Carrozza, Maria Chiara

    2010-01-01

    This paper presents the preliminary design of a new dexterous upper-limb prosthesis provided with a novel anthropomorphic hand, a compact wrist based on bevel gears and a modular forearm able to cover different levels of upper-limb amputations. The hand has 20 DoFs and 11 motors, with a dexterous three fingered subsystem composed by a fully actuated thumb, and an hybrid index and middle fingers to enable dexterous manipulation and enhance grasp performance.

  7. DEXTER: Disease-Expression Relation Extraction from Text.

    Science.gov (United States)

    Gupta, Samir; Dingerdissen, Hayley; Ross, Karen E; Hu, Yu; Wu, Cathy H; Mazumder, Raja; Vijay-Shanker, K

    2018-01-01

    Gene expression levels affect biological processes and play a key role in many diseases. Characterizing expression profiles is useful for clinical research, and diagnostics and prognostics of diseases. There are currently several high-quality databases that capture gene expression information, obtained mostly from large-scale studies, such as microarray and next-generation sequencing technologies, in the context of disease. The scientific literature is another rich source of information on gene expression-disease relationships that not only have been captured from large-scale studies but have also been observed in thousands of small-scale studies. Expression information obtained from literature through manual curation can extend expression databases. While many of the existing databases include information from literature, they are limited by the time-consuming nature of manual curation and have difficulty keeping up with the explosion of publications in the biomedical field. In this work, we describe an automated text-mining tool, Disease-Expression Relation Extraction from Text (DEXTER) to extract information from literature on gene and microRNA expression in the context of disease. One of the motivations in developing DEXTER was to extend the BioXpress database, a cancer-focused gene expression database that includes data derived from large-scale experiments and manual curation of publications. The literature-based portion of BioXpress lags behind significantly compared to expression information obtained from large-scale studies and can benefit from our text-mined results. We have conducted two different evaluations to measure the accuracy of our text-mining tool and achieved average F-scores of 88.51 and 81.81% for the two evaluations, respectively. Also, to demonstrate the ability to extract rich expression information in different disease-related scenarios, we used DEXTER to extract information on differential expression information for 2024 genes in lung

  8. An orthologue of the cor gene is involved in the exclusion of temperate lambdoid phages. Evidence that Cor inactivates FhuA receptor functions

    International Nuclear Information System (INIS)

    Uc-Mass, Augusto; Loeza, Eva Jacinto; Garza, Mireya de la; Guarneros, Gabriel; Hernandez-Sanchez, Javier; Kameyama, Luis

    2004-01-01

    A new set of lambdoid phages (mEp) classified into different immunity groups was previously described. Phages mEp213, mEp237, and mEp410 were unable to grow in mEp167 lysogenic cells, presumably due to an exclusion mechanism expressed constitutively by the mEp167 repressed prophage. In this work, to analyze the exclusion phenomenon, we constructed a genomic library from mEp167 phage in a pPROEX derivative plasmid. A DNA fragment containing an open reading frame for a 77 amino acid polypeptide was selected by its ability to confer resistance to heteroimmune phage infection. This ORF shows high amino acid sequence identity with putative Cor proteins of phages HK022, φ80 and N15. Cells expressing the mEp167 cor gene from a plasmid (Cor + phenotype) excluded 13 of 20 phages from different infection immunity groups. This exclusion was observed in both tonB - and tonB + cells. Lambdoid mEp phages that were excluded in these cells were unable to infect cells defective in the outer membrane FhuA receptor (fhuA - ). Thus, Cor-mediated exclusion was only observed in fhuA + cells. Phage production after DNA transfection or the spontaneous induction of mEp prophage in Cor + cells was not blocked. In addition, ferrichrome uptake, which is mediated by FhuA, was inhibited in Cor + cells. Our results show that not only phage infection via FhuA but also a FhuA transport activity (ferrichrome uptake) are inhibited by Cor, presumably by inactivation of FhuA

  9. Isolation and expression pattern of COR15b and KIN1 genes in ...

    African Journals Online (AJOL)

    sequences of COR15b and KIN1 genes were firstly isolated from leaves of watermelon (Citrullus lanatus) and pumpkin (Cucurbita moschata). Sequencing results indicated that the open reading fragments (ORF) of COR15b in watermelon (ClCOR15b) and COR15b in pumpkin (CmCOR15b) were 348 and 426 bp, which ...

  10. Reliability and validity of a new dexterity questionnaire (DextQ-24) in Parkinson's disease

    NARCIS (Netherlands)

    Vanbellingen, Tim; Nyffeler, Thomas; Nef, Tobias; Kwakkel, Gert; Bohlhalter, Stephan; van Wegen, Erwin E.H.

    2016-01-01

    Background Patients with Parkinson's disease exhibit disturbed dexterity. Validated self-reported outcomes for dexterity in Parkinson's disease are lacking. The aim of this study was to investigate the reliability, content and construct validity of a new Dexterity Questionnaire 24. Methods One

  11. Complex Hand Dexterity: A Review of Biomechanical Methods for Measuring Musical Performance

    Directory of Open Access Journals (Sweden)

    Cheryl Diane Metcalf

    2014-05-01

    Full Text Available Complex hand dexterity is fundamental to our interactions with the physical, social and cultural environment. Dexterity can be an expression of creativity and precision in a range of activities, including musical performance. Little is understood about complex hand dexterity or how virtuoso expertise is acquired, due to the versatility of movement combinations available to complete any given task. This has historically limited progress of the field because of difficulties in measuring movements of the hand. Recent developments in methods of motion capture and analysis mean it is now possible to explore the intricate movements of the hand and fingers. These methods allow us insights into the neurophysiological mechanisms underpinning complex hand dexterity and motor learning. They also allow investigation into the key factors that contribute to injury, recovery and functional compensation.The application of such analytical techniques within musical performance provides a multidisciplinary framework for purposeful investigation into the process of learning and skill acquisition in instrumental performance. These highly skilled manual and cognitive tasks present the ultimate achievement in complex hand dexterity. This paper will review methods of assessing instrumental performance in music, focusing specifically on biomechanical measurement and the associated technical challenges faced when measuring highly dexterous activities.

  12. OpenCOR: a modular and interoperable approach to computational biology

    Directory of Open Access Journals (Sweden)

    Alan eGarny

    2015-02-01

    Full Text Available Computational biologists have been developing standards and formats for nearly two decades, with the aim of easing the description and exchange of experimental data, mathematical models, simulation experiments, etc. One of those efforts is CellML (cellml.org, an XML-based markup language for the encoding of mathematical models.Early CellML-based environments include COR and OpenCell. However, both of those tools have limitations and were eventually replaced with OpenCOR (opencor.ws. OpenCOR is an open source modeling environment that is supported on Windows, Linux and OS X. It relies on a modular approach, which means that all of its features come in the form of plugins. Those plugins can be used to organize, edit, simulate and analyze models encoded in the CellML format.We start with an introduction to CellML and two of its early adopters, which limitations eventually led to the development of OpenCOR. We then go onto describing the general philosophy behind OpenCOR, as well as describing its openness and its development process. Next, we illustrate various aspects of OpenCOR, such as its user interface and some of the plugins that come bundled with it (e.g. its editing and simulation plugins. Finally, we discuss some of the advantages and limitations of OpenCOR before drawing some concluding remarks.

  13. THE HEIGHT EVOLUTION OF THE ''TRUE'' CORONAL MASS EJECTION MASS DERIVED FROM STEREO COR1 AND COR2 OBSERVATIONS

    International Nuclear Information System (INIS)

    Bein, B. M.; Temmer, M.; Veronig, A. M.; Utz, D.; Vourlidas, A.

    2013-01-01

    Using combined STEREO-A and STEREO-B EUVI, COR1, and COR2 data, we derive deprojected coronal mass ejection (CME) kinematics and CME ''true'' mass evolutions for a sample of 25 events that occurred during 2007 December to 2011 April. We develop a fitting function to describe the CME mass evolution with height. The function considers both the effect of the coronagraph occulter, at the beginning of the CME evolution, and an actual mass increase. The latter becomes important at about 10-15 R ☉ and is assumed to mostly contribute up to 20 R ☉ . The mass increase ranges from 2% to 6% per R ☉ and is positively correlated to the total CME mass. Due to the combination of COR1 and COR2 mass measurements, we are able to estimate the ''true'' mass value for very low coronal heights ( ☉ ). Based on the deprojected CME kinematics and initial ejected masses, we derive the kinetic energies and propelling forces acting on the CME in the low corona ( ☉ ). The derived CME kinetic energies range between 1.0-66 × 10 23 J, and the forces range between 2.2-510 × 10 14 N.

  14. Selección natural sobre a cor das flores de Gentiana lutea L.

    OpenAIRE

    Veiga Blanco, Tania

    2015-01-01

    A variación floral dentro dunha de especie pode resultar da variación espacial nos axentes de selección. A cor floral podería variar pola selección dos animais que se alimentan das plantas. Os polinizadores poderían exercer selección natural sobre a cor, si a cor inflúe na eficacia do consumo. Outros axentes de selección, como os predadores de sementes, poderían seleccionar sobre a cor, si a cor indica recursos alimentarios (sementes) ou si a cor está relacionada con defensas químicas. Así, a...

  15. Effects of Dexterity Level and Hand Anthropometric Dimensions on Smartphone Users’ Satisfaction

    Directory of Open Access Journals (Sweden)

    N. Firat Ozkan

    2015-01-01

    Full Text Available The usage of smartphones instead of simple mobile phones increases sharply in our era, especially among young people, because they do multiple tasks with single equipment. This study mainly focuses on smartphone satisfaction by combining hand measurements, smartphone users’ survey results, and hand dexterity levels of corresponding users acquired from Minnesota Manual Dexterity Test (MMDT. Structural Equation Modelling (SEM is used as a statistical tool to discover the potential direct and indirect relations among user satisfaction, hand dimensions, and dexterity scores. Results indicates that thumb length, hand length, and dexterity level of the users have notable effects on users’ satisfaction with smartphones. Based on the results, a new approach that includes both gross motor skills and physical measurements is suggested to see hidden indirect relations with satisfaction.

  16. A CASE OF COR BILOCULARE ACCOMPANIED BY POLYSPLENIA

    Directory of Open Access Journals (Sweden)

    M. S. ROJHAN

    1972-07-01

    Full Text Available The clinical history and necroscopic fi ndings of a 3 -} year old girl - involved in cor biloculare was reported. In th is case dextrotransposition of the great a rteries and polysplenia was observed. The majority of cor biloculare cases appearing in the literature being accompanied by asplenia, the present case of polysplenia is relatively rare

  17. COR V2: teaching observational research with multimedia courseware.

    Science.gov (United States)

    Blasko, Dawn G; Kazmerski, Victoria A; Torgerson, Carla N

    2004-05-01

    Courseware for Observational Research (COR Version 2) is an interactive multimedia program designed to teach the foundation of the scientific method: systematic observation. COR uses digital video with interactive coding to teach basic concepts, such as creating precise operational definitions; using frequency, interval, and duration coding; developing sampling strategies; and analyzing and interpreting data. Through lessons, a case study, and laboratory exercises, it gradually scaffolds students from teacher-directed learning into self-directed learning. The newest addition to COR is a case study in which students work collaboratively, using their own observations to make recommendations about a child's disruptive behavior in an after-school program. Evaluations of the lessons showed that classes using COR received better grades on their field observations than did those using methods that are more traditional. Students' confidence and knowledge increased as they moved through each section of the program.

  18. Sofrimento psíquico na perversão: o caso dexter El sufrimiento psíquico en la perversión: el caso dexter Psychic suffering in perversion: the dexter affair

    Directory of Open Access Journals (Sweden)

    Fábio Roberto Rodrigues Belo

    2012-09-01

    Full Text Available A análise do personagem fictício Dexter permite construir hipóteses metapsicológicas sobre as origens da perversão. A posição perversa nesse caso deve-se à presença maciça de violência nas origens do sujeito psíquico. Dexter expressa o abandono sofrido pela atuação pulsional, os assassinatos em série, tentando inverter o estado de passividade no qual se encontra. Sua angústia pode ser organizada de duas formas distintas: a primeira é consciente, fornecida por seu pai, Harry, que o ensina a não deixar vestígios dos seus crimes. A segunda maneira é inconsciente, e traduz o desejo de submeter o outro à dor, fazendo com que, por meio do mecanismo de identificação projetiva, o perverso desfrute deste sofrimento que provoca, sendo remetido, então, às suas vivências originárias de submissão. Conclui-se que na perversão a angústia não apenas está presente, como também é constitutiva da escolha do sujeito de operar pela via da violência.El análisis del personaje ficticio Dexter permite la construcción de hipótesis metapsicológicas sobre los orígenes de la perversión. La posición perversa en este caso se debe a la presencia masiva de la violencia en los orígenes del sujeto psíquico. Dexter expresa el abandono sufrido a través de una actuación pulsional, los asesinatos en serie, intentando invertir el estado de pasividad en el que se encuentra. Su angustia puede ser organizada de dos maneras distintas: la primera es consciente, proporcionada por su padre, Harry, quien le enseña a no dejar rastros de sus crímenes. La segunda es inconsciente, y traduce el deseo de someter al otro al dolor, haciendo con que, a través del mecanismo de la identificación proyectiva, el perverso disfrute del sufrimiento que provoca, siendo remitido, así, a sus experiencias originarias de sumisión. Concluimos que, en la perversión, la angustia no sólo está presente, sino que es constitutiva de la elección del sujeto de operar

  19. 75 FR 10241 - Town of Dexter; Notice of Declaration of Intention and Soliciting Comments, Protests, and/or...

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. DI10-7-000] Town of Dexter.... Date Filed: February 16, 2010. d. Applicant: Town of Dexter. e. Name of Project: Dexter Hydroelectric Project. f. Location: The proposed Dexter Hydroelectric Project will be located on the East Branch...

  20. MOTORIC SPEED AND MANUAL DEXTERITY OF CHILDERN WITH IMPAIRED VISION

    Directory of Open Access Journals (Sweden)

    Dženana Radžo Alibegović

    2017-04-01

    Full Text Available The aim of this study was to estimate the motoric speed and manual dexterity of children with visual impairments. The research is covered by a sample size of 35 participants with visual impairment, with ages between 7 and 15 years, of which 19 participants with visual impairment were male and 16 participants with impaired vision were female. The study was conducted in 17 primary schools in the municipality of Tuzla, Bosnia and Herzegovina. The results showed that the motoric speed and manual dexterity of children with visual impairment is evenly developed on the right and left hand, and also on both hands together and that there is a relationship between the motoric speed and manual dexterity of the right and left hand and both hands together.

  1. Bulldog dwarfism in Dexter cattle is caused by mutations in ACAN.

    Science.gov (United States)

    Cavanagh, Julie A L; Tammen, Imke; Windsor, Peter A; Bateman, John F; Savarirayan, Ravi; Nicholas, Frank W; Raadsma, Herman W

    2007-11-01

    Bulldog dwarfism in Dexter cattle is one of the earliest single-locus disorders described in animals. Affected fetuses display extreme disproportionate dwarfism, reflecting abnormal cartilage development (chondrodysplasia). Typically, they die around the seventh month of gestation, precipitating a natural abortion. Heterozygotes show a milder form of dwarfism, most noticeably having shorter legs. Homozygosity mapping in candidate regions in a small Dexter pedigree suggested aggrecan (ACAN) as the most likely candidate gene. Mutation screening revealed a 4-bp insertion in exon 11 (2266_2267insGGCA) (called BD1 for diagnostic testing) and a second, rarer transition in exon 1 (-198C>T) (called BD2) that cosegregate with the disorder. In chondrocytes from cattle heterozygous for the insertion, mutant mRNA is subject to nonsense-mediated decay, showing only 8% of normal expression. Genotyping in Dexter families throughout the world shows a one-to-one correspondence between genotype and phenotype at this locus. The heterozygous and homozygous-affected Dexter cattle could prove invaluable as a model for human disorders caused by mutations in ACAN.

  2. Hand and finger dexterity as a function of skin temperature, EMG, and ambient condition.

    Science.gov (United States)

    Chen, Wen-Lin; Shih, Yuh-Chuan; Chi, Chia-Fen

    2010-06-01

    This article examines the changes in skin temperature (finger, hand, forearm), manual performance (hand dexterity and strength), and forearm surface electromyograph (EMG) through 40-min, 11 degrees C water cooling followed by 15-min, 34 degrees C water rewarming; additionally, it explores the relationship between dexterity and the factors of skin temperature, EMG, and ambient condition. Hand exposure in cold conditions is unavoidable and significantly affects manual performance. Two tasks requiring gross and fine dexterity were designed, namely, nut loosening and pin insertion, respectively. The nested-factorial design includes factors of gender, participant (nested within gender), immersion duration, muscle type (for EMG), and location (for skin temperature). The responses are changes in dexterity, skin temperature, normalized amplitude of EMG, and grip strength. Finally, factor analysis and stepwise regression are used to explore factors affecting hand and finger dexterity. Dexterity, EMG, and skin temperature fell with prolonged cooling, but the EMG of the flexor digitorum superficialis remained almost unchanged during the nut loosening task. All responses but the forearm skin temperature recovered to the baseline level at the end of rewarming. The three factors extracted by factor analysis are termed skin temperature, ambient condition, and EMG. They explain approximately two thirds of the variation of the linear models for both dexterities, and the factor of skin temperature is the most influential. Sustained cooling and warming significantly decreases and increases finger, hand, and forearm skin temperature. Dexterity, strength, and EMG are positively correlated to skin temperature. Therefore, keeping the finger, hand, and forearm warm is important to maintaining hand performance. The findings could be helpful to building safety guidelines for working in cold environments.

  3. The right atrium: gateway to the heart--anatomic and pathologic imaging findings.

    Science.gov (United States)

    Malik, Sachin B; Kwan, Damon; Shah, Amar B; Hsu, Joe Y

    2015-01-01

    Knowledge of right atrial anatomic and pathologic imaging findings and associated clinical symptoms is important to avoid false-positive diagnoses and missed findings. Complete evaluation of the heart often requires a multimodality approach that includes radiography, echocardiography, computed tomography (CT), magnetic resonance (MR) imaging, and invasive angiography. In general, CT provides the highest spatial resolution of these modalities at the cost of radiation exposure to the patient. Echocardiography and MR imaging offer complementary and detailed information for functional evaluation without added radiation exposure. The advantages and disadvantages of each modality for the evaluation of right atrial anatomic structure, size, and pathologic findings are discussed. Cardiac MR imaging is the reference standard for evaluation of right atrial size and volume but often is too time consuming and resource intensive to perform in routine clinical practice. Therefore, established reference ranges for two-dimensional transthoracic echocardiography are often used. Right atrial pathologic findings can be broadly categorized into (a) congenital anomalies (cor triatriatum dexter, Ebstein anomaly, and aneurysm), (b) disorders of volume (tricuspid regurgitation, pathologic mimics such as a pseudoaneurysm, and atrial septal defect), (c) disorders of pressure (tricuspid stenosis, restrictive cardiomyopathy, and constrictive pericarditis), and (d) masses (pseudomasses, thrombus, lipomatous hypertrophy of the interatrial septum, lipoma, myxoma, sarcoma, and metastatic disease). Familiarity with each pathologic entity and its treatment options is essential to ensure that appropriate imaging modalities are selected. Online supplemental material is available for this article. RSNA, 2015

  4. Task specificity of finger dexterity tests

    NARCIS (Netherlands)

    Berger, M.A.M.; Krul, A.; Daanen, H.A.M.

    2009-01-01

    Finger dexterity tests are generally used to assess performance decrease due to gloves, cold and pathology. It is generally assumed that the O’Connor and Purdue Pegboard test yield similar results. In this experiment we compared these two tests for dry conditions without gloves, and for dry and wet

  5. Task specificity of finger dexterity tests

    NARCIS (Netherlands)

    Berger, M.A.M.; Krul, A.J.; Daanen, H.A.M.

    2009-01-01

    Finger dexterity tests are generally used to assess performance decrease due to gloves, cold and pathology. It is generally assumed that the O'Connor and Purdue Pegboard test yield similar results. In this experiment we compared these two tests for dry conditions without gloves, and for dry and wet

  6. Automation of motor dexterity assessment.

    Science.gov (United States)

    Heyer, Patrick; Castrejon, Luis R; Orihuela-Espina, Felipe; Sucar, Luis Enrique

    2017-07-01

    Motor dexterity assessment is regularly performed in rehabilitation wards to establish patient status and automatization for such routinary task is sought. A system for automatizing the assessment of motor dexterity based on the Fugl-Meyer scale and with loose restrictions on sensing technologies is presented. The system consists of two main elements: 1) A data representation that abstracts the low level information obtained from a variety of sensors, into a highly separable low dimensionality encoding employing t-distributed Stochastic Neighbourhood Embedding, and, 2) central to this communication, a multi-label classifier that boosts classification rates by exploiting the fact that the classes corresponding to the individual exercises are naturally organized as a network. Depending on the targeted therapeutic movement class labels i.e. exercises scores, are highly correlated-patients who perform well in one, tends to perform well in related exercises-; and critically no node can be used as proxy of others - an exercise does not encode the information of other exercises. Over data from a cohort of 20 patients, the novel classifier outperforms classical Naive Bayes, random forest and variants of support vector machines (ANOVA: p home-based virtual rehabilitation and telerehabilitation alternatives.

  7. A novel method for the quantification of key components of manual dexterity after stroke

    OpenAIRE

    T?r?metz, Maxime; Colle, Florence; Hamdoun, Sonia; Maier, Marc A.; Lindberg, P?vel G.

    2015-01-01

    Background A high degree of manual dexterity is a central feature of the human upper limb. A rich interplay of sensory and motor components in the hand and fingers allows for independent control of fingers in terms of timing, kinematics and force. Stroke often leads to impaired hand function and decreased manual dexterity, limiting activities of daily living and impacting quality of life. Clinically, there is a lack of quantitative multi-dimensional measures of manual dexterity. We therefore ...

  8. Increasing The Dexterity Of Redundant Robots

    Science.gov (United States)

    Seraji, Homayoun

    1990-01-01

    Redundant coordinates used to define additional tasks. Configuration control emerging as effective way to control motions of robot having more degrees of freedom than necessary to define trajectory of end effector and/or of object to be manipulated. Extra or redundant degrees of freedom used to give robot humanlike dexterity and versatility.

  9. Coréia aguda na gravidez

    Directory of Open Access Journals (Sweden)

    Walter C. Pereira

    1967-12-01

    Full Text Available São apresentados doze casos de coréia aguda observados entre 150.000 gestantes (1/12.500. A maioria dos surtos ocorreu no segundo trimestre da primeira gravidez. A duração média dos sintomas foi de três meses, não tendo sido registrado caso algum de óbito materno. Todos os partos foram espontâneos e normais. Houve apenas um óbito fetal conseqüente a choque hemorrágico. São tecidas considerações a propósito dos aspectos clínico, laboratorial e prognóstico da coréia gravídica, sendo focalizado mais pormenorizadamente o problema fisiopatogênico dessa afecção.

  10. A questão ontológica da percepção de cor

    Directory of Open Access Journals (Sweden)

    Elton Hiroshi Matsushima

    2001-01-01

    Full Text Available O presente estudo focaliza as questões sobre a ontologia da cor, essencialmente a discussão entre Fisicalismo e Subjetivismo. Analisando estes debates, entre uma concepção físicalista, que considera a cor uma propriedade física dos objetos externos, e uma concepção subjetivista, em que a cor é identificada com um processamento mental, encontrou-se argumentação diversa, desde questões silogísticas até evidências experimentais. Entretanto, uma hipótese alternativa é oferecida, o Psicofisicalismo, em que evidências da psicofísica da cor e modelos evolucionários fornecem uma descrição da essência da cor. A cor deve ser considerada uma propriedade dual, com uma vertente física e uma psicológica estreitamente relacionadas.

  11. Qualitative Analysis of a Cultural Dexterity Program for Surgeons: Feasible, Impactful, and Necessary.

    Science.gov (United States)

    Udyavar, Rhea; Smink, Douglas S; Mullen, John T; Kent, Tara S; Green, A; Harlow, Alyssa F; Castillo-Angeles, Manuel; Columbus, Alexandra B; Haider, Adil H

    2018-02-15

    Ineffective cross-cultural communication contributes to adverse outcomes for minority patients. To address this, the authors developed a novel curriculum for surgical residents built on the principle of cultural dexterity, emphasizing adaptability to clinical and sociocultural circumstances to tailor care to the needs of the individual patient. This study's objective was to evaluate the feasibility, acceptability, and perception of this program upon conclusion of its first year. The curriculum was implemented at 3 general surgery programs. The flipped classroom model combined independent study via e-learning modules with interactive role-playing sessions. Sessions took place over 1 academic year. Four focus groups were held, each with 6 to 9 participants, to gain feedback on the curriculum. Focus groups were recorded and transcribed, and the data were analyzed using a grounded theory approach. Five major themes emerged: (1) Role modeling from senior colleagues is integral in developing communication/interpersonal skills and attitudes toward cultural dexterity. (2) Cultural dexterity is relevant to the provision of high-quality surgical care. (3) Barriers to providing culturally dexterous care exist at the system level. (4) "Buy-in" at all levels of the institution is necessary to implement the principles of cultural dexterity. (5) The shared experience of discussing the challenges and triumphs of caring for a diverse population was engaging and impactful. Early implementation of the curriculum revealed that the tension between surgical residents' desire to improve their cultural dexterity and systemic/practical obstacles can be resolved. Combining surgically relevant didactic materials with experiential learning activities can change the paradigm of cross-cultural training. Copyright © 2018 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  12. Isolation and expression pattern of COR15b and KIN1 genes in ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-11-02

    Nov 2, 2009 ... COR15b and KIN1 (COR 6.5) genes encode polypeptides of 15 KDa and 6.5 KDa, respectively. They are involved in the dehydration tolerance mechanisms and play important role under cold stress. cDNA sequences of COR15b and KIN1 genes were firstly isolated from leaves of watermelon (Citrullus.

  13. Toward a Dexter-based model for open hypermedia: Unifying embedded references and link objects

    DEFF Research Database (Denmark)

    Grønbæk, Kaj; Trigg, Randall Hagner

    1996-01-01

    Nominated for the Doug Engelbart best paper award. This paper discusses experiences and lessons learned from the design of an open hypermedia system, one that integrates applications and data not ''owned'' by the hypermedia. The Dexter Hypertext Reference Model was used as the basis for the design....... Though our experiences were generally positive, we found the model constraining in certain ways and underdeveloped in others. For instance, Dexter argues against dangling links, but we found several situations where permitting and supporting dangling links was advisable. In Dexter, the data objects...

  14. Molecular mechanism of Mg2+-dependent gating in CorA

    Science.gov (United States)

    Dalmas, Olivier; Sompornpisut, Pornthep; Bezanilla, Francisco; Perozo, Eduardo

    2014-04-01

    CorA is the major transport system responsible for Mg2+ uptake in bacteria and can functionally substitute for its homologue Mrs2p in the yeast inner mitochondrial membrane. Although several CorA crystal structures are available, the molecular mechanism of Mg2+ uptake remains to be established. Here we use electron paramagnetic resonance spectroscopy, electrophysiology and molecular dynamic simulations to show that CorA is regulated by cytoplasmic Mg2+ acting as a ligand and elucidate the basic conformational rearrangements responsible for Mg2+-dependent gating. Mg2+ unbinding at the divalent cation sensor triggers a conformational change that leads to the inward motion of the stalk helix, which propagates to the pore-forming transmembrane helix TM1. Helical tilting and rotation in TM1 generates an iris-like motion that increases the diameter of the permeation pathway, triggering ion conduction. This work establishes the molecular basis of a Mg2+-driven negative feedback loop in CorA as the key physiological event controlling Mg2+ uptake and homeostasis in prokaryotes.

  15. Hit Dexter: A Machine-Learning Model for the Prediction of Frequent Hitters.

    Science.gov (United States)

    Stork, Conrad; Wagner, Johannes; Friedrich, Nils-Ole; de Bruyn Kops, Christina; Šícho, Martin; Kirchmair, Johannes

    2018-03-20

    False-positive assay readouts caused by badly behaving compounds-frequent hitters, pan-assay interference compounds (PAINS), aggregators, and others-continue to pose a major challenge to experimental screening. There are only a few in silico methods that allow the prediction of such problematic compounds. We report the development of Hit Dexter, two extremely randomized trees classifiers for the prediction of compounds likely to trigger positive assay readouts either by true promiscuity or by assay interference. The models were trained on a well-prepared dataset extracted from the PubChem Bioassay database, consisting of approximately 311 000 compounds tested for activity on at least 50 proteins. Hit Dexter reached MCC and AUC values of up to 0.67 and 0.96 on an independent test set, respectively. The models are expected to be of high value, in particular to medicinal chemists and biochemists who can use Hit Dexter to identify compounds for which extra caution should be exercised with positive assay readouts. Hit Dexter is available as a free web service at http://hitdexter.zbh. uni-hamburg.de. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Conflitos de gerações: Gustavo Corção e a juventude católica (Generation conflict: Gustavo Corção and Catholic Youth

    Directory of Open Access Journals (Sweden)

    Christiane Jalles de Paula

    2012-07-01

    Full Text Available Este artigo aborda o combate que empreendeu Gustavo Corção à juventude católica brasileira nas páginas do Diário de Notícias e d’ O Globo entre as décadas de 1950 e de 1960. No caso em tela, interessa-nos entender as reações de Gustavo Corção às mudanças na sociedade e na Igreja Católica entre 1957 e 1964. A hipótese é que as críticas de Corção explicitam o conflito entre duas gerações de católicos: uma conservadora; a dele; e outra progressista, a das organizações de jovens católicos, mais especificamente, a da Juventude Universitária Católica (JUC. Apresentaremos a disputa a partir do exame da seguinte questão: o papel que a juventude brasileira deveria desempenhar naqueles anos. O objetivo é mostrar que suas críticas à opção de ação temporal assumida pelas organizações de juventude católica devem ser lidas pela chave do conflito geracional que marcou o campo católico brasileiro. Palavras-chave: Catolicismo. Gerações. Gustavo Corção. Juventude católica.   Abstract: This paper discusses the fight of Brazilian Catholic Youth Gustavo Corção in the newspapers Diário de Notícias and O Globo in the 1950s and 1960s. In case we are interested in understanding the reactions of Gustavo Corção to changes in society and the Catholic Church between 1957 and 1964. The hypothesis is that the criticism of Corção explains the conflict between two generations of Catholics: a conservative and other progressive, represented by the Catholic youth organizations, more specifically, the Youth Catholic University. We are going to examine the question: the role that Brazilian youth should play in those years. Therefore, the aim is to show that his criticism of the political action undertaken by the young catholic organizations should be read by the key of generation conflict which has marked the Brazilian Catholic field. Keywords: Catholicism. Generations. Gustavo Corção. Catholic youth organizations.

  17. A cor e a moda : a função da cor como suporte para o design de moda e personalidade dentro de um público jovem

    OpenAIRE

    Pina, Liliana Maria Gonçalves

    2009-01-01

    Ao longo da evolução do ser humano este sempre se auxiliou da cor para seu benefício nas mais diversas etapas. Explorar a relação cor/moda e cor/personalidade foi, desde o início, um dos principais motivos para a escolha de um tema para esta dissertação. Desde sempre o consumidor, necessitou de se vestir, desde sempre teve vontade de experimentar coisas novas, contrastes e harmonias onde o seu modo de ser e personalidade se poderiam inserir. Mas por vezes, e sendo o ser h...

  18. Force and touch make video games 'serious' for dexterity rehabilitation.

    Science.gov (United States)

    Confalonieri, Michele; Guandalini, Giovanni; Da Lio, Mauro; De Cecco, Mariolino

    2012-01-01

    Computerized interfaces are able to represent 3D immersive simulations. Most of them make use of joystick, mouse, gloves, or grasp pressure transducers. Those have the drawback of 'filtering' the user interaction and/or de-locate the touch with respect to the visual stimulus. To overcome this we developed dexterity rehabilitation games on a novel touch interface that measures also force. The system allows dexterity training through 'direct' manipulation of virtual objects in 3D. Two dimensions via the touch screen, the third by the force channel. Tactile feedback is provided with a vibration device mounted on the screen back.

  19. Deficits in Visuo-Motor Temporal Integration Impacts Manual Dexterity in Probable Developmental Coordination Disorder.

    Science.gov (United States)

    Nobusako, Satoshi; Sakai, Ayami; Tsujimoto, Taeko; Shuto, Takashi; Nishi, Yuki; Asano, Daiki; Furukawa, Emi; Zama, Takuro; Osumi, Michihiro; Shimada, Sotaro; Morioka, Shu; Nakai, Akio

    2018-01-01

    The neurological basis of developmental coordination disorder (DCD) is thought to be deficits in the internal model and mirror-neuron system (MNS) in the parietal lobe and cerebellum. However, it is not clear if the visuo-motor temporal integration in the internal model and automatic-imitation function in the MNS differs between children with DCD and those with typical development (TD). The current study aimed to investigate these differences. Using the manual dexterity test of the Movement Assessment Battery for Children (second edition), the participants were either assigned to the probable DCD (pDCD) group or TD group. The former was comprised of 29 children with clumsy manual dexterity, while the latter consisted of 42 children with normal manual dexterity. Visuo-motor temporal integration ability and automatic-imitation function were measured using the delayed visual feedback detection task and motor interference task, respectively. Further, the current study investigated whether autism-spectrum disorder (ASD) traits, attention-deficit hyperactivity disorder (ADHD) traits, and depressive symptoms differed among the two groups, since these symptoms are frequent comorbidities of DCD. In addition, correlation and multiple regression analyses were performed to extract factors affecting clumsy manual dexterity. In the results, the delay-detection threshold (DDT) and steepness of the delay-detection probability curve, which indicated visuo-motor temporal integration ability, were significantly prolonged and decreased, respectively, in children with pDCD. The interference effect, which indicated automatic-imitation function, was also significantly reduced in this group. These results highlighted that children with clumsy manual dexterity have deficits in visuo-motor temporal integration and automatic-imitation function. There was a significant correlation between manual dexterity, and measures of visuo-motor temporal integration, and ASD traits and ADHD traits and

  20. Interfaces et reconfigurations de la question Nord/Sud en Corée.

    Directory of Open Access Journals (Sweden)

    Valérie Gelézeau

    2010-12-01

    Full Text Available S’appuyant sur un travail pluridisciplinaire autour de la notion d’interface, l’article propose de nouvelles perspectives d’analyse de la question Nord/Sud en Corée en considérant la partition entre Corée du Nord et Corée du Sud non plus comme un simple contexte géopolitique mais comme une matrice structurante des deux sociétés. Trois grands types d’interfaces entre les deux Corées sont identifiés et analysés à travers plusieurs études de cas : les interfaces spatiales (la frontière inter-coréenne, la frontière sino-nord-coréenne, ou encore les enclaves économiques développées au Nord par la Corée du Sud, les interfaces sociales (la communauté des Nord-Coréens au Sud, les élites sud-coréennes originaires du Nord, ou les échanges culturels nés de l’introduction au Sud de la peinture nord-coréenne, les interfaces narratives renvoyant aux discours que chaque Corée construit sur l’Autre, que ce soient les discours officiels (manuels scolaires, agences de presse ou ceux de la fiction (cinéma. Prolongeant le travail des géographes sur la notion, l’article s’efforce de mieux décrire la géométrie du système que constitue une interface (multiplicité des plans et des niveaux de contacts, jeu des synapses et des interstices, prégnance des enclaves non seulement sur le plan spatial mais aussi sur les plans social et narratif et de reconsidérer l’extraordinaire complexité de la culture coréenne contemporaine. Malgré les divergences de vues sur l’existence même d’une interface entre les deux Corées, l’article conclut que l’usage de ce concept a contribué à mettre en évidence la prégnance de cette division au cœur des deux Corées, à tous les niveaux de la sphère sociale et jusque dans le discours des études coréennes. En exposant les frontières divisant les discours et les savoirs sur la péninsule selon un paradigme bipolaire, le concept d’interface a pu permettre de

  1. Contradictions within a Knotworking session of an interior décor project

    DEFF Research Database (Denmark)

    Rasmussen, Mai; Jensen, Rasmus Lund; Svidt, Kjeld

    actors with an interest in the specific ‘knot’ (Engeström 2008). Moreover this presentation presents an analysis of contradictions within a Knotworking session of an interior décor project. The interior décor project is targeted a new building for Department of Civil Engineering at Aalborg University...... in Denmark aiming to generate an ownership among the users of the building. Through this presentation the audience will discover advantages and disadvantages of the utilization of Knotowkring as a method for making interior décor at a Danish University. Moreover, the audience will notify Knotworking...... been utilized in contexts as the library, hospital and construction industry. By investigating Knotworking in the context of interior décor through an analysis by activity theory systems, this research contributes to knowledge about contradictions within a Knotworking session and potential solutions...

  2. Not all resources are created equal: COR theory, values, and stress.

    Science.gov (United States)

    Morelli, Neil A; Cunningham, Christopher J L

    2012-01-01

    The common usage of conservation of resources (COR) theory highlights the quantity of resources in explaining stress reactions and responses. To expand the theoretical understanding and explanatory power of COR theory, this study tested the proposition that the perceived importance of an individual's resources is a function of personal values. Using a value framework based on Schwartz (1994), it was expected that values would influence both the appraisal of resource importance and coping behaviors. Results from both student and working samples indicated that while resource importance did not clearly mediate all of the coping outcomes, values did have an influence on the importance an individual assigns to resources. Measurement and theoretical implications related to COR theory are discussed.

  3. Conflitos de gerações: Gustavo Corção e a juventude católica (Generation conflict: Gustavo Corção and Catholic Youth)

    OpenAIRE

    Paula, Christiane Jalles de; Fundação Getulio Vargas

    2012-01-01

    Este artigo aborda o combate que empreendeu Gustavo Corção à juventude católica brasileira nas páginas do Diário de Notícias e d’ O Globo entre as décadas de 1950 e de 1960. No caso em tela, interessa-nos entender as reações de Gustavo Corção às mudanças na sociedade e na Igreja Católica entre 1957 e 1964. A hipótese é que as críticas de Corção explicitam o conflito entre duas gerações de católicos: uma conservadora; a dele; e outra progressista, a das organizações de jovens católicos, mais ...

  4. Determination of the relationship between cognitive function and hand dexterity in patients with chronic obstructive pulmonary disease (COPD): a cross-sectional study.

    Science.gov (United States)

    Soysal Tomruk, Melda; Ozalevli, Sevgi; Dizdar, Gorkem; Narin, Selnur; Kilinc, Oguz

    2015-07-01

    Hand dexterity is important for daily living activities and can be related to cognitive functions in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the relationship between cognitive dysfunction and hand dexterity in patients with COPD. 35 COPD patients and 36 healthy individuals were assessed. The Minnesota Hand Dexterity Test and Mini Mental State Examination (MMSE) were used for assessment of cognitive function and hand dexterity. Hand dexterity test scores and cognitive function of COPD patients' were significantly lower than the healthy group (p COPD group (p COPD; however, hand dexterity did not alter according to hypoxemia severity. Hand dexterity which is important in daily living activities should be evaluated in greater detail with further studies in COPD patients.

  5. An Instrumented Glove to Assess Manual Dexterity in Simulation-Based Neurosurgical Education

    Directory of Open Access Journals (Sweden)

    Juan Diego Lemos

    2017-04-01

    Full Text Available The traditional neurosurgical apprenticeship scheme includes the assessment of trainee’s manual skills carried out by experienced surgeons. However, the introduction of surgical simulation technology presents a new paradigm where residents can refine surgical techniques on a simulator before putting them into practice in real patients. Unfortunately, in this new scheme, an experienced surgeon will not always be available to evaluate trainee’s performance. For this reason, it is necessary to develop automatic mechanisms to estimate metrics for assessing manual dexterity in a quantitative way. Authors have proposed some hardware-software approaches to evaluate manual dexterity on surgical simulators. This paper presents IGlove, a wearable device that uses inertial sensors embedded on an elastic glove to capture hand movements. Metrics to assess manual dexterity are estimated from sensors signals using data processing and information analysis algorithms. It has been designed to be used with a neurosurgical simulator called Daubara NS Trainer, but can be easily adapted to another benchtop- and manikin-based medical simulators. The system was tested with a sample of 14 volunteers who performed a test that was designed to simultaneously evaluate their fine motor skills and the IGlove’s functionalities. Metrics obtained by each of the participants are presented as results in this work; it is also shown how these metrics are used to automatically evaluate the level of manual dexterity of each volunteer.

  6. Dexterity: A MATLAB-based analysis software suite for processing and visualizing data from tasks that measure arm or forelimb function.

    Science.gov (United States)

    Butensky, Samuel D; Sloan, Andrew P; Meyers, Eric; Carmel, Jason B

    2017-07-15

    Hand function is critical for independence, and neurological injury often impairs dexterity. To measure hand function in people or forelimb function in animals, sensors are employed to quantify manipulation. These sensors make assessment easier and more quantitative and allow automation of these tasks. While automated tasks improve objectivity and throughput, they also produce large amounts of data that can be burdensome to analyze. We created software called Dexterity that simplifies data analysis of automated reaching tasks. Dexterity is MATLAB software that enables quick analysis of data from forelimb tasks. Through a graphical user interface, files are loaded and data are identified and analyzed. These data can be annotated or graphed directly. Analysis is saved, and the graph and corresponding data can be exported. For additional analysis, Dexterity provides access to custom scripts created by other users. To determine the utility of Dexterity, we performed a study to evaluate the effects of task difficulty on the degree of impairment after injury. Dexterity analyzed two months of data and allowed new users to annotate the experiment, visualize results, and save and export data easily. Previous analysis of tasks was performed with custom data analysis, requiring expertise with analysis software. Dexterity made the tools required to analyze, visualize and annotate data easy to use by investigators without data science experience. Dexterity increases accessibility to automated tasks that measure dexterity by making analysis of large data intuitive, robust, and efficient. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Cold habituation does not improve manual dexterity during rest and exercise in 5 °C

    Science.gov (United States)

    Muller, Matthew D.; Seo, Yongsuk; Kim, Chul-Ho; Ryan, Edward J.; Pollock, Brandon S.; Burns, Keith J.; Glickman, Ellen L.

    2014-04-01

    When exposed to a cold environment, a barehanded person experiences pain, cold sensation, and reduced manual dexterity. Both acute (e.g. exercise) and chronic (e.g. cold acclimatization or habituation) processes might lessen these negative effects. The purpose of this experiment was to determine the effect of cold habituation on physiology, perception, and manual dexterity during rest, exercise, and recovery in 5 °C. Six cold weather athletes (CWA) and eight non habituated men (NON) volunteered to participate in a repeated measures cross-over design. The protocol was conducted in 5 °C and was 90 min of resting cold exposure, 30 min of cycle ergometry exercise (50 % VO2 peak), and 60 min of seated recovery. Core and finger skin temperature, metabolic rate, Purdue Pegboard dexterity performance, hand pain, thermal sensation, and mood were quantified. Exercise-induced finger rewarming (EIFRW) was calculated for each hand. During 90 min of resting exposure to 5 °C, the CWA had a smaller reduction in finger temperature, a lower metabolic rate, less hand pain, and less negative mood. Despite this cold habituation, dexterity performance was not different between groups. In response to cycle ergometry, EIFRW was greater in CWA (~12 versus 7 °C) and occurred at lower core temperatures (37.02 versus 37.31 °C) relative to NON but dexterity was not greater during post-exercise recovery. The current data indicate that cold habituated men (i.e., CWA) do not perform better on the Purdue Pegboard during acute cold exposure. Furthermore, despite augmented EIFRW in CWA, dexterity during post-exercise recovery was similar between groups.

  8. Higher Plasma Myostatin Levels in Cor Pulmonale Secondary to Chronic Obstructive Pulmonary Disease.

    Science.gov (United States)

    Ju, Chun-Rong; Chen, Miao; Zhang, Jian-Heng; Lin, Zhi-Ya; Chen, Rong-Chang

    2016-01-01

    To analyze plasma myostatin levels and investigate their relationship with right ventricular (RV) function in patients with cor pulmonale secondary to chronic obstructive pulmonary disease (COPD). The study recruited 81 patients with advanced COPD and 40 age-matched controls. The patients were divided into two groups: those with cor pulmonale and those without. Echocardiography was used to evaluate RV function and morphology, and the value of tricuspid annular plane systolic excursion (TAPSE) less than 16 mm was considered RV dysfunction. Plasma myostatin levels were analyzed by enzyme-linked immunosorbent assay, and B-type natriuretic peptide (BNP) levels were analyzed as a comparison of myostatin. The data detected cor pulmonale in 39/81 patients, with the mean value of TAPSE of 14.3 mm. Plasma myostatin levels (ng/mL) were significantly higher in patients with cor pulmonale (16.68 ± 2.95) than in those without (13.56 ± 3.09), and much higher than in controls (8.79±2.79), with each pmyostatin levels were significantly correlated with the values of TAPSE and RV myocardium performance index among the COPD patients, and that BNP levels were significantly correlated only with systolic pulmonary arterial pressure, with each pmyostatin levels are increased in COPD patients who have cor pulmonale. Stronger correlations of plasma myostatin levels with echocardiographic indexes of the right heart suggest that myostatin might be superior to BNP in the early diagnosis of cor pulmonale in COPD.

  9. Combined motor point associative stimulation (MPAS) and transcranial direct current stimulation (tDCS) improves plateaued manual dexterity performance.

    Science.gov (United States)

    Hoseini, Najmeh; Munoz-Rubke, Felipe; Wan, Hsuan-Yu; Block, Hannah J

    2016-10-28

    Motor point associative stimulation (MPAS) in hand muscles is known to modify motor cortex excitability and improve learning rate, but not plateau of performance, in manual dexterity tasks. Central stimulation of motor cortex, such as transcranial direct current stimulation (tDCS), can have similar effects if accompanied by motor practice, which can be difficult and tiring for patients. Here we asked whether adding tDCS to MPAS could improve manual dexterity in healthy individuals who are already performing at their plateau, with no motor practice during stimulation. We hypothesized that MPAS could provide enough coordinated muscle activity to make motor practice unnecessary, and that this combination of stimulation techniques could yield improvements even in subjects at or near their peak. If so, this approach could have a substantial effect on patients with impaired dexterity, who are far from their peak. MPAS was applied for 30min to two right hand muscles important for manual dexterity. tDCS was simultaneously applied over left sensorimotor cortex. The motor cortex input/output (I/O) curve was assessed with transcranial magnetic stimulation (TMS), and manual dexterity was assessed with the Purdue Pegboard Test. Compared to sham or cathodal tDCS combined with MPAS, anodal tDCS combined with MPAS significantly increased the plateau of manual dexterity. This result suggests that MPAS has the potential to substitute for motor practice in mediating a beneficial effect of tDCS on manual dexterity. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  10. Carcinoma bilateral do plexo coróide operado com sucesso

    Directory of Open Access Journals (Sweden)

    Gilberto M. de Almeida

    1970-06-01

    Full Text Available Os autores não encontraram na literatura caso de carcinoma bilateral do plexo coróide operado com sucesso. O trabalho consta da apresentação de uma criança de 11 anos com carcinoma dos plexos coróides nos dois ventrículos laterais. São feitas considerações a respeito das dificuldades no diagnóstico, da importância dó estudo angiográfico completo e do tratamento

  11. Behavioral coping and physical functioning: The effect of adjusting the level of activity on observed dexterity

    NARCIS (Netherlands)

    Lankveld, W.G.J.M. van; Näring, G.W.B.; Pad Bosch, P. van 't; Putte, L.B.A. van de

    1999-01-01

    Objective. To assess the relationship between behavioral coping and dexterity in rheumatoid arthritis (RA) after controlling for disease activity, impairment of the hands, and pain. Methods. A random sample of 109 patients with RA was assessed twice within one year. Dexterity, disease activity, and

  12. Material properties of CorCap passive cardiac support device.

    Science.gov (United States)

    Chitsaz, Sam; Wenk, Jonathan F; Ge, Liang; Wisneski, Andrew; Mookhoek, Aart; Ratcliffe, Mark B; Guccione, Julius M; Tseng, Elaine E

    2013-01-01

    Myocardial function deteriorates during ventricular remodeling in patients with congestive heart failure (HF). Ventricular restraint therapy using a cardiac support device (CSD) is designed to reduce the amount of stress inside the dilated ventricles, which in turn halts remodeling. However, as an open mesh surrounding the heart, it is unknown what the mechanical properties of the CSD are in different fiber orientations. Composite specimens of CorCap (Acorn Cardiovascular, Inc, St. Paul, MN) CSD fabric and silicone were constructed in different fiber orientations and tested on a custom-built biaxial stretcher. Silicone controls were made and stretched to detect the parameters of the matrix. CSD coefficients were calculated using the composite and silicone matrix stress-strain data. Stiffness in different fiber orientations was determined. Silicone specimens exerted a linear behavior, with stiffness of 2.57 MPa. For the composites with 1 fiber set aligned with respect to the stretch axes, stiffness in the direction of the aligned fiber set was higher than that in the cross-fiber direction (14.39 MPa versus 5.66 MPa), indicating greater compliance in the cross-fiber direction. When the orientation of the fiber sets in the composite were matched to the expected clinical orientation of the implanted CorCap, the stiffness in the circumferential axis (with respect to the heart) was greater than in the longitudinal axis (10.55 MPa versus 9.70 MPa). The mechanical properties of the CorCap demonstrate directionality with greater stiffness circumferentially than longitudinally. Implantation of the CorCap clinically should take into account the directionality of the biomechanics to optimize ventricular restraint. Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  13. AbioCor totally implantable artificial heart. How will it impact hospitals?

    Science.gov (United States)

    2002-09-01

    Although heart transplantation remains the most effective treatment for severe heart failure, there are far fewer donor hearts available than there are patients who could benefit from them. One approach to addressing this shortfall is the total artificial heart, or TAH. To date, however, no TAH design has been able to achieve one of the ultimate goals of heart replacement: to allow a patient to live a reasonably normal life without being connected to external machinery. A new design, the AbioCor TAH developed by Abiomed Inc., may make this goal achievable. Thanks to a power system that transfers energy through the skin without the aid of wires, the AbioCor--currently undergoing clinical trials in the United States--allows the patient to be completely mobile. The lack of transcutaneous wires also eliminates the primary source of the infections that have plagued TAH patients in the past. Though it is not without drawbacks, the AbioCor could represent a crucial advance in TAH technology. In this Technology Overview, we describe the operation of the AbioCor and discuss its likely impact on hospitals if it is approved for marketing in the United States. We also discuss a related cardiac-support technology: ventricular assist devices (VADs), which may also be used for permanent cardiac support someday.

  14. Eyeball Measurement of Dexterity: Tests as Alternatives to Interviews.

    Science.gov (United States)

    Guion, Robert M.; Imada, Andrew S.

    1981-01-01

    Reports a study conducted for litigation in a sex discrimination case dealing with misuse of an employment interview. Results show that dexterity could not be determined in an interview and a more appropriate selection technique such as a test was required. (Author/JAC)

  15. Purification and crystallization of Cor a 9, a major hazelnut allergen

    International Nuclear Information System (INIS)

    Guo, Feng; Kothary, Mahendra H.; Wang, Yang; Yu, Xiaoping; Howard, Andrew J.; Fu, Tong-Jen; Zhang, Yu-Zhu

    2008-01-01

    The major hazelnut allergen Cor a 9 was purified from the natural source and crystallized. Diffraction data were collected to 1.9 Å resolution using a synchrotron-radiation source. Hazelnut (Corylus avellana) is one of the food sources that induce allergic reaction in a subpopulation of people with food allergy. The 11S legumin-like seed-storage protein from hazelnut has been identified as one of the major hazelnut allergens and named Cor a 9. In this study, Cor a 9 was extracted from hazelnut kernels using a high-salt solution and was purified by desalting out and FPLC to a highly purified state. Diffraction-quality single crystals were obtained using the hanging-drop vapour-diffusion method. Diffraction data were collected and a structure solution has been obtained by molecular-replacement calculations. Further refinement of the structure is currently in progress

  16. Clinical course of cor pulmonale investigated after an interval of one year by thallium-201 myocardial SPECT scintigraphy

    International Nuclear Information System (INIS)

    Yamaoka, Shimpachi; Nishimura, Kouichi; Kuno, Kenshi; Yonekura, Yoshiharu; Koide, Harutoshi.

    1988-01-01

    Cor pulmonale was evaluated in 13 patients with chronic lung disease by thallium-201 myocardial SPECT scintigraphy together with pulmonary function tests and right heart catheterization. One year later, we performed this scintigraphy again to investigate the clinical course of the cor pulmonale. In 6 of 13 patients with respiratory failure (Pao 2 less than 60 Torr), a remarkable progression in cor pulmonale was noted after one year, despite outpatient oxygen therapy. If the patients were admitted because of acute exacerbation of respiratory failure, the cor pulmonale was found to have worsened. In contrast, patients with acute exacerbation due to respiratory infection or causes other than respiratory failure, showed little change in cor pulmonale. Although patients with a marked progression of cor pulmonale tended to have poor pulmonary function data and elevated pulmonary arterial pressure, the clinical course of cor pulmonale could not be predicted from the initial pulmonary function tests or right heart catheterization. (author)

  17. Expression analysis and functional characterization of a novel cold-responsive gene CbCOR15a from Capsella bursa-pastoris.

    Science.gov (United States)

    Zhou, Mingqi; Wu, Lihua; Liang, Jing; Shen, Chen; Lin, Juan

    2012-05-01

    The cold-responsive (COR) genes involved in C-repeat binding factor signaling pathway function essentially in cold acclimation of higher plants. A novel COR gene CbCOR15a from shepherd's purse (Capsella bursa-pastoris) was predicted to be a homolog of COR15 in Arabidopsis. The analysis of tissue specific expression pattern as well as characterization of the CbCOR15a promoter revealed that the expression of CbCOR15a was induced by coldness not only in leaves and stem but also in roots. Sequence analysis showed that a 909 bp promoter region of CbCOR15a contained two CRT/DRE elements, two ABRE elements, one auxin-responsive TGA-element and one MeJA-responsive CGTCA-motif. In young seedlings the expression of CbCOR15a could be apparently increased by SA, ABA, MeJA and IAA, and transiently increased by GA(3) accompanied by obvious feedback suppression. According to the altered physiological index values in tobacco under cold treatments, the overexpression of CbCOR15a significantly increased the cold tolerance of transgenic tobacco plants. It can be suggested that CbCOR15a was involved in cold response of Capsella bursa-pastoris associated with SA, ABA, MeJA, IAA and GA(3) regulation and confers enhanced cold acclimation in transgenic plants.

  18. Higher Plasma Myostatin Levels in Cor Pulmonale Secondary to Chronic Obstructive Pulmonary Disease.

    Directory of Open Access Journals (Sweden)

    Chun-Rong Ju

    Full Text Available To analyze plasma myostatin levels and investigate their relationship with right ventricular (RV function in patients with cor pulmonale secondary to chronic obstructive pulmonary disease (COPD.The study recruited 81 patients with advanced COPD and 40 age-matched controls. The patients were divided into two groups: those with cor pulmonale and those without. Echocardiography was used to evaluate RV function and morphology, and the value of tricuspid annular plane systolic excursion (TAPSE less than 16 mm was considered RV dysfunction. Plasma myostatin levels were analyzed by enzyme-linked immunosorbent assay, and B-type natriuretic peptide (BNP levels were analyzed as a comparison of myostatin.The data detected cor pulmonale in 39/81 patients, with the mean value of TAPSE of 14.3 mm. Plasma myostatin levels (ng/mL were significantly higher in patients with cor pulmonale (16.68 ± 2.95 than in those without (13.56 ± 3.09, and much higher than in controls (8.79±2.79, with each p<0.01. Significant differences were also found in plasma BNP levels among the three groups (p<0.05. Multivariate regression analysis suggested that myostatin levels were significantly correlated with the values of TAPSE and RV myocardium performance index among the COPD patients, and that BNP levels were significantly correlated only with systolic pulmonary arterial pressure, with each p<0.05.Plasma myostatin levels are increased in COPD patients who have cor pulmonale. Stronger correlations of plasma myostatin levels with echocardiographic indexes of the right heart suggest that myostatin might be superior to BNP in the early diagnosis of cor pulmonale in COPD.

  19. A novel cold-regulated gene from Camellia sinensis, CsCOR1, enhances salt- and dehydration-tolerance in tobacco

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xian-Wen, E-mail: xianwenli01@sina.com [College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); College of Life Science, Xinyang Normal University, Xinyang 464000 (China); Key Laboratory of Horticultural Plant Biology of the Ministry of Education, Huazhong Agricultural University, Wuhan 430070 (China); Feng, Zhi-Guo; Yang, Hui-Min; Zhu, Xiao-Pei [College of Life Science, Xinyang Normal University, Xinyang 464000 (China); Liu, Jun, E-mail: liujun@mail.hzau.edu.cn [College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); Key Laboratory of Horticultural Plant Biology of the Ministry of Education, Huazhong Agricultural University, Wuhan 430070 (China); Yuan, Hong-Yu, E-mail: yhongyu92@163.com [College of Life Science, Xinyang Normal University, Xinyang 464000 (China)

    2010-04-02

    In present research, the full-length cDNA and the genomic sequence of a novel cold-regulated gene, CsCOR1, were isolated from Camellia sinensis L. The deduced protein CsCOR1 contains a hydrophobic N-terminus as a signal peptide and a hydrophilic C-terminal domain that is rich in glycine, arginine and proline. Two internal repetitive tridecapeptide fragments (HSVTAGRGGYNRG) exist in the middle of the C-terminal domain and the two nucleotide sequences encoding them are identical. CsCOR1 was localized in the cell walls of transgenic-tobaccos via CsCOR1::GFP fusion approach. The expression of CsCOR1 in tea leaves was enhanced dramatically by both cold- and dehydration-stress. And overexpression of CsCOR1 in transgenic-tobaccos improved obviously the tolerance to salinity and dehydration.

  20. Terapêutica hormonal na coréia de Sydenham

    Directory of Open Access Journals (Sweden)

    José Geraldo Albernaz

    1957-09-01

    Full Text Available Cinco casos de coréia de Sydenham foram submetidos à terapêutica hormonal com Cortisona, Prednisona e Prednisolona; o fenobarbital e a clorpromazina foram utilizados como medicação sintomática e a Penicilina-Benzatina como profilática. Depois de analisadas as referências bibliográficas, comparados os resultados de ν;rios autores, e ajuizados os resultados obtidos em nossos casos, acreditamos poder concluir que: 1 a terapêutica hormonal da coréia de Sydenham, com o uso de ACTH, Cortisona, Prednisona ou Pred-nisclona apresenta resultados satisfatórios; 2 a Prednisona e a Prednisolona são os hormônios mais úteis no tratamento da coréia de Sydenham, sendo possível que sua associação aos salicilatos permita obter resultados ainda melhores; 3 o tratamento deve prolongar-se até o completo desaparecimento dos sintomas, as doses variando de acôrdo com a gravidade e a evolução da moléstia; 4 a terapêutica hormonal deve ser usada sem prejuízo de medicação sintomática (sedativa e profilática (antibiótica.

  1. A motion-planning method for dexterous hand operating a tool based on bionic analysis

    Directory of Open Access Journals (Sweden)

    Wei Bo

    2017-01-01

    Full Text Available In order to meet the needs of robot’s operating tools for different types and sizes, the dexterous hand is studied by many scientific research institutions. However, the large number of joints in a dexterous hand leads to the difficulty of motion planning. Aiming at this problem, this paper proposes a planning method abased on BPNN inspired by human hands. Firstly, this paper analyses the structure and function of the human hand and summarizes its typical strategy of operation. Secondly, based on the manual operation strategy, the tools are classified according to the shape and the operation mode of the dexterous hand is presented. Thirdly, the BPNN is used to train the humanoid operation, and then output the operation plan. Finally, the simulating experiments of grasping simple tools and operating complex tools are made by MATLAB and ADAMS. The simulation verifies the effectiveness of this method.

  2. Atrofia girata de coróide e retina : relato de caso

    Directory of Open Access Journals (Sweden)

    Oyamaguchi Emerson Kenji

    2003-01-01

    Full Text Available OBJETIVO: Relatar um caso de atrofia girata de coróide e retina com confirmação por meio da bioquímica do plasma. MÉTODO: Aferiu-se a melhor acuidade visual corrigida de ambos olhos (AO em tabela de Snellen. Foram realizados biomicroscopia do segmento anterior, refração, mapeamento de retina, angiografia fluoresceínica, campo visual e dosagem da ornitina sérica (aminoacidograma. RESULTADOS: Paciente de 22 anos, sexo feminino, cor branca, apresentando alta miopia e acuidade visual (AV 20/100 em AO. À biomicroscopia do segmento anterior apresentava catarata subcapsular posterior em AO. À oftalmoscopia foram verificadas lesões atróficas da coróide e da retina bem delimitadas em meia periferia de AO. O aminoacidograma constatou elevação correspondente ao complexo da ornitina. CONCLUSÃO: Relata-se um caso típico de atrofia girata, distrofia retiniana rara associada a hiperornitinemia.

  3. A smartphone-based system to quantify dexterity in Parkinson's disease patients

    Directory of Open Access Journals (Sweden)

    Somayeh Aghanavesi

    2017-01-01

    Conclusions: Quantifying PD motor symptoms via instrumented, dexterity tests employed in a smartphone is feasible and data from such tests can also be used for measuring treatment-related changes in patients.

  4. Comparison of the effect of using latex and nitrile gloves hand dexterity among Iranian population

    Directory of Open Access Journals (Sweden)

    T. Allahyari

    2014-02-01

    .Conclusion: Considering that there was no significant difference in the score of both fine finger and gross hand dexterity while using nitrile gloves as compared to the control condition (without gloves, means that use of nitrile gloves has no adverse effect on hand dexterity therefore, using nitrile gloves is recommended as a alternative for the latex gloves, considering the additional advantage of no allergic reaction in this gloves.

  5. Assessing the effects of manual dexterity and playing computer games on catheter-wire manipulation for inexperienced operators.

    Science.gov (United States)

    Alsafi, Z; Hameed, Y; Amin, P; Shamsad, S; Raja, U; Alsafi, A; Hamady, M S

    2017-09-01

    To investigate the effect of playing computer games and manual dexterity on catheter-wire manipulation in a mechanical aortic model. Medical student volunteers filled in a preprocedure questionnaire assessing their exposure to computer games. Their manual dexterity was measured using a smartphone game. They were then shown a video clip demonstrating renal artery cannulation and were asked to reproduce this. All attempts were timed. Two-tailed Student's t-test was used to compare continuous data, while Fisher's exact test was used for categorical data. Fifty students aged 18-22 years took part in the study. Forty-six completed the task at an average of 168 seconds (range 103-301 seconds). There was no significant difference in the dexterity score or time to cannulate the renal artery between male and female students. Students who played computer games for >10 hours per week had better dexterity scores than those who did not play computer games: 9.1 versus 10.2 seconds (p=0.0237). Four of 19 students who did not play computer games failed to complete the task, while all of those who played computer games regularly completed the task (p=0.0168). Playing computer games is associated with better manual dexterity and ability to complete a basic interventional radiology task for novices. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  6. 48 CFR 1352.201-72 - Contracting Officer's Representative (COR).

    Science.gov (United States)

    2010-10-01

    ... COR is also responsible for the final inspection and acceptance of all deliverables and such other... otherwise obligate the Government or authorize any changes which affect the contract price, terms or...

  7. Changes in corticospinal drive to spinal motoneurones following tablet-based practice of manual dexterity

    DEFF Research Database (Denmark)

    Larsen, Lisbeth Højkjær; Jensen, Thor; Christensen, Mark Schram

    2016-01-01

    ) between EEG-EMG and EMG-EMG activity. Following motor practice performance improved significantly and a significant increase in EEG-EMGAPB and EMGAPB-EMGFDI coherence in the beta band (15-30 Hz) was observed. No changes were observed after the control session. Our results show that tablet-based motor...... practice is associated with changes in the common corticospinal drive to spinal motoneurons involved in manual dexterity. Tablet-based motor practice may be a motivating training tool for stroke patients who struggle with loss of dexterity....

  8. A restructuring of COR package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The COR package, which calculates the thermal response of the core and the lower plenum internal structures and models the relocation of the core and lower plenum structural materials, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To do this, the data transferring methods of the current MELCOR code are modified and adopted into the COR package. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as well as a waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which leads to an efficient memory treatment and an easy understanding of the code. Restructuring of the COR package addressed in this paper includes a module development, subroutine modification. The verification has been done by comparing the results of the modified code with those of the existing code. As the trends are similar to each other, it implies that the same approach could be extended to the entire code package. It is expected that the code restructuring will accelerated the code's domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  9. Cor a 14, the allergenic 2S albumin from hazelnut, is highly thermostable and resistant to gastrointestinal digestion

    Science.gov (United States)

    Pfeifer, Sabine; Bublin, Merima; Dubiela, Pawel; Hummel, Karin; Wortmann, Judith; Hofer, Gerhard; Keller, Walter; Radauer, Christian

    2015-01-01

    Scope Allergens from nuts frequently induce severe allergic reactions in sensitive individuals. The aim of this study was to elucidate the physicochemical characteristics of natural Cor a 14, the 2S albumin from hazelnut. Methods and results Cor a 14 was purified from raw hazelnuts using a combination of precipitation and chromatographic techniques. The protein was analyzed using gel electrophoresis, MS, and far‐UV circular dichroism (CD) analyses. The immunoglobulin E (IgE) binding of native, heat‐treated, and in vitro digested Cor a 14 was studied. We identified two different Cor a 14 isoforms and showed microclipping at the C‐terminus. CD spectra at room temperature showed the typical characteristics of 2S albumins, and temperatures of more than 80°C were required to start unfolding of Cor a 14 demonstrating its high stability to heat treatment. In vitro digestion experiments revealed that Cor a 14 is resistant to proteolytic degradation. Native and heat‐treated protein was recognized by sera from hazelnut allergic patients. However, denaturation of the allergen led to significantly reduced IgE binding. Conclusion We identified two different isoforms of Cor a 14 displaying high stability under heating and gastric and duodenal conditions. Data from IgE‐binding experiments revealed the existence of both, linear and conformational epitopes. PMID:26178695

  10. Cor a 14 is the superior serological marker for hazelnut allergy in children, independent of concomitant peanut allergy.

    Science.gov (United States)

    Eller, E; Mortz, C G; Bindslev-Jensen, C

    2016-04-01

    Hazelnut is the most frequent cause of tree nut allergy, but up to half of all children with hazelnut allergy additionally suffer from peanut allergy. Our aim was to identify diagnostic values of the most promising serological markers (Cor a 9 and Cor a 14) and to address the influence of concomitant peanut allergy and PR10 sensitization. We included 155 children suspected of hazelnut allergy and challenged according to the guidelines. Concomitant allergy to peanuts was verified or ruled out by challenge. Skin prick test, s-IgE and CRD to hazelnut, peanut, PR10 and LPT protein families were measured using ImmunoCAP. Sixty-five children had a positive hazelnut challenge, and 60% of these also had a concomitant peanut allergy. Children allergic to hazelnut were sensitized to Cor a 9 and Cor a 14; peanut-allergic children were sensitized to Ara h 2. Sensitization to PR10 protein components was seen in 45% of all included children, irrelevant to allergy to peanut or hazelnut. A cut-off >0.72 kU/L of IgE towards Cor a 14 diagnosed 87% correctly, making Cor a 14 the superior serology marker. However, nine hazelnut-allergic children were primarily sensitized to Cor a 9. Concomitant peanut allergy is common in hazelnut-allergic children, but decision points as well as diagnostic values for Cor a 14 are not affected. We found three independent and well-characterized serotypes; hazelnut-allergic children were sensitized to Cor a 14, peanut-allergic children were sensitized to Ara h 2, and independently of this were children sensitized to birch pollen (Bet v 1). © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. A novel cold-regulated gene from Phlox subulata, PsCor413im1, enhances low temperature tolerance in Arabidopsis.

    Science.gov (United States)

    Zhou, Aimin; Sun, Hongwei; Feng, Shuang; Zhou, Mi; Gong, Shufang; Wang, Jingang; Zhang, Shuzhen

    2018-01-08

    Low temperature stress adversely affects plant growth, development, and crop productivity. Analysis of the function of genes in the response of plants to low temperature stress is essential for understanding the mechanism of chilling and freezing tolerance. In this study, PsCor413im1, a novel cold-regulated gene isolated from Phlox subulata, was transferred to Arabidopsis to investigate its function under low temperature stress. Real-time quantitative PCR analysis revealed that PsCor413im1 expression was induced by cold and abscisic acid. Subcellular localization revealed that PsCor413im1-GFP fusion protein was localized to the periphery of the chloroplast, consistent with the localization of chloroplast inner membrane protein AtCor413im1, indicating that PsCor413im1 is a chloroplast membrane protein. Furthermore, the N-terminal of PsCor413im1 was determined to be necessary for its localization. Compared to the wild-type plants, transgenic plants showed higher germination and survival rates under cold and freezing stress. Moreover, the expression of AtCor15 in transgenic plants was higher than that in the wild-type plants under cold stress. Taken together, our results suggest that the overexpression of PsCor413im1 enhances low temperature tolerance in Arabidopsis. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Usability of Videogame-Based Dexterity Training in the Early Rehabilitation Phase of Stroke Patients: A Pilot Study.

    Science.gov (United States)

    Vanbellingen, Tim; Filius, Suzanne J; Nyffeler, Thomas; van Wegen, Erwin E H

    2017-01-01

    Approximately 70-80% of stroke survivors have limited activities of daily living, mainly due to dexterous problems. Videogame-based training (VBT) along with virtual reality seems to be beneficial to train upper limb function. To evaluate the usability of VBT using the Leap Motion Controller (LMC) to train fine manual dexterity in the early rehabilitation phase of stroke patients as an add-on to conventional therapy. Additionally, this study aimed to estimate the feasibility and potential efficacy of the VBT. During 3 months, 64 stroke patients were screened for eligibility, 13 stroke patients were included (4 women and 9 men; age range: 24-91 years; mean time post stroke: 28.2 days). Nine sessions of 30 min VBT, three times per week as an add-on to conventional therapy with stroke inpatients. Primary outcome was the usability of the system measured with the System Usability Scale. Secondary outcomes concerning feasibility were the compliance rate calculated from the total time spent on the intervention (TT) compared to planned time, the opinion of participants via open-end questions, and the level of active participation measured with the Pittsburgh Rehabilitation Participation Scale. Regarding the potential efficacy secondary outcomes were: functional dexterity measured with the Nine Hole Peg Test (NHPT), subjective dexterity measured with the Dexterity Questionnaire 24, grip strength measured with the Jamar dynamometer, and motor impairment of the upper limb measured with the Fugl-Meyer Upper Extremity (FM-UE) scale. Primarily, the usability of the system was good to excellent. The patient's perception of usability remained stable over a mean period of 3 weeks of VBT. Secondly, the compliance rate was good, and the level of active participation varied between good and very good. The opinion of the participants revealed that despite individual differences, the overall impression of the therapy and device was good. Patients showed significant

  13. Usability of Videogame-Based Dexterity Training in the Early Rehabilitation Phase of Stroke Patients: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Tim Vanbellingen

    2017-12-01

    Full Text Available BackgroundApproximately 70–80% of stroke survivors have limited activities of daily living, mainly due to dexterous problems. Videogame-based training (VBT along with virtual reality seems to be beneficial to train upper limb function.ObjectiveTo evaluate the usability of VBT using the Leap Motion Controller (LMC to train fine manual dexterity in the early rehabilitation phase of stroke patients as an add-on to conventional therapy. Additionally, this study aimed to estimate the feasibility and potential efficacy of the VBT.MethodsDuring 3 months, 64 stroke patients were screened for eligibility, 13 stroke patients were included (4 women and 9 men; age range: 24–91 years; mean time post stroke: 28.2 days.InterventionNine sessions of 30 min VBT, three times per week as an add-on to conventional therapy with stroke inpatients.Outcome measuresPrimary outcome was the usability of the system measured with the System Usability Scale. Secondary outcomes concerning feasibility were the compliance rate calculated from the total time spent on the intervention (TT compared to planned time, the opinion of participants via open-end questions, and the level of active participation measured with the Pittsburgh Rehabilitation Participation Scale. Regarding the potential efficacy secondary outcomes were: functional dexterity measured with the Nine Hole Peg Test (NHPT, subjective dexterity measured with the Dexterity Questionnaire 24, grip strength measured with the Jamar dynamometer, and motor impairment of the upper limb measured with the Fugl-Meyer Upper Extremity (FM-UE scale.ResultsPrimarily, the usability of the system was good to excellent. The patient’s perception of usability remained stable over a mean period of 3 weeks of VBT. Secondly, the compliance rate was good, and the level of active participation varied between good and very good. The opinion of the participants revealed that despite individual differences, the overall impression

  14. Relationship between manual dexterity and the unified parkinson's disease rating scale-motor exam.

    Science.gov (United States)

    Hwang, Sujin; Song, Chiang-Soon

    2016-12-01

    [Purpose] The purpose of this study was to examine the relationships between manual dexterity and the Unified Parkinson's Disease Rating Scale-Motor Exam as a clinical tool for quantifying upper extremity function in persons with Parkinson's disease. [Subjects and Methods] Thirty-two persons with idiopathic Parkinson's disease participated in this study. This study measured two clinical outcomes, the box-and-block test and the Unified Parkinson's Disease Rating Scale-Motor Exam, to investigate the relationships between manual dexterity and the Unified Parkinson's Disease Rating Scale-Motor Exam. [Results] The box-and-block test on the more affected side was positive relationship with the box-and-block test on the less affected side. The Unified Parkinson's Disease Rating Scale-motor exam score had a negative correlation with the box-and-block test results for both sides. [Conclusion] A positive association was noted between manual dexterity and motor function in patients with idiopathic Parkinson disease. The results of this study suggest that the box-and-block test and the Unified Parkinson's Disease Rating Scale-Motor Exam are good clinical measures that quantify upper extremity function and are necessary for the accurate evaluation of patients and to plan intervention strategies.

  15. GNSS CORS hardware and software enabling new science

    Science.gov (United States)

    Drummond, P.

    2009-12-01

    GNSS CORS networks are enabling new opportunities for science and public and private sector business. This paper will explore how the newest geodetic monitoring software and GNSS receiver hardware from Trimble Navigation Ltd are enabling new science. Technology trends and science opportunities will be explored. These trends include the installation of active GNSS control, automation of observations and processing, and the advantages of multi-observable and multi-constellation observations, all performed with the use of off the shelf products and industry standard open-source data formats. Also the possibilities with moving science from an after-the-fact postprocessed model to a real-time epoch-by-epoch solution will be explored. This presentation will also discuss the combination of existing GNSS CORS networks with project specific installations used for monitoring. Experience is showing GNSS is able to provide higher resolution data than previous methods, providing new tools for science, decision makers and financial planners.

  16. Highly dexterous 2-module soft robot for intra-organ navigation in minimally invasive surgery.

    Science.gov (United States)

    Abidi, Haider; Gerboni, Giada; Brancadoro, Margherita; Fras, Jan; Diodato, Alessandro; Cianchetti, Matteo; Wurdemann, Helge; Althoefer, Kaspar; Menciassi, Arianna

    2018-02-01

    For some surgical interventions, like the Total Mesorectal Excision (TME), traditional laparoscopes lack the flexibility to safely maneuver and reach difficult surgical targets. This paper answers this need through designing, fabricating and modelling a highly dexterous 2-module soft robot for minimally invasive surgery (MIS). A soft robotic approach is proposed that uses flexible fluidic actuators (FFAs) allowing highly dexterous and inherently safe navigation. Dexterity is provided by an optimized design of fluid chambers within the robot modules. Safe physical interaction is ensured by fabricating the entire structure by soft and compliant elastomers, resulting in a squeezable 2-module robot. An inner free lumen/chamber along the central axis serves as a guide of flexible endoscopic tools. A constant curvature based inverse kinematics model is also proposed, providing insight into the robot capabilities. Experimental tests in a surgical scenario using a cadaver model are reported, demonstrating the robot advantages over standard systems in a realistic MIS environment. Simulations and experiments show the efficacy of the proposed soft robot. Copyright © 2017 John Wiley & Sons, Ltd.

  17. CorVue algorithm efficacy to predict heart failure in real life: Unnecessary and potentially misleading information?

    Science.gov (United States)

    Palfy, Julia Anna; Benezet-Mazuecos, Juan; Milla, Juan Martinez; Iglesias, Jose Antonio; de la Vieja, Juan Jose; Sanchez-Borque, Pepa; Miracle, Angel; Rubio, Jose Manuel

    2018-06-01

    Heart failure (HF) hospitalizations have a negative impact on quality of life and imply important costs. Intrathoracic impedance (ITI) variations detected by cardiac devices have been hypothesized to predict HF hospitalizations. Although Optivol™ algorithm (Medtronic) has been widely studied, CorVue™ algorithm (St. Jude Medical) long term efficacy has not been systematically evaluated in a "real life" cohort. CorVue™ was activated in ICD/CRT-D patients to store information about ITI measures. Clinical events (new episodes of HF requiring treatment and hospitalizations) and CorVue™ data were recorded every three months. Appropriate CorVue™ detection for HF was considered if it occurred in the four prior weeks to the clinical event. 53 ICD/CRT-D (26 ICD and 27 CRT-D) patients (67±1 years-old, 79% male) were included. Device position was subcutaneous in 28 patients. At inclusion, mean LVEF was 25±7% and 27 patients (51%) were in NYHA class I, 18 (34%) class II and 8 (15%) class III. After a mean follow-up of 17±9 months, 105 ITI drops alarms were detected in 32 patients (60%). Only six alarms were appropriate (true positive) and required hospitalization. Eighteen patients (34%) presented 25 clinical episodes (12 hospitalizations and 13 ER/ambulatory treatment modifications). Nineteen of these clinical episodes (76%) remained undetected by the CorVue™ (false negative). Sensitivity of CorVue™ resulted in 24%, specificity was 70%, positive predictive value of 6% and negative predictive value of 93%. CorVue™ showed a low sensitivity to predict HF events. Therefore, routinely activation of this algorithm could generate misleading information. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  18. Combining Stereo SECCHI COR2 and HI1 Images for Automatic CME Front Edge Tracking

    Science.gov (United States)

    Kirnosov, Vladimir; Chang, Lin-Ching; Pulkkinen, Antti

    2016-01-01

    COR2 coronagraph images are the most commonly used data for coronal mass ejection (CME) analysis among the various types of data provided by the STEREO (Solar Terrestrial Relations Observatory) SECCHI (Sun-Earth Connection Coronal and Heliospheric Investigation) suite of instruments. The field of view (FOV) in COR2 images covers 215 solar radii (Rs) that allow for tracking the front edge of a CME in its initial stage to forecast the lead-time of a CME and its chances of reaching the Earth. However, estimating the lead-time of a CME using COR2 images gives a larger lead-time, which may be associated with greater uncertainty. To reduce this uncertainty, CME front edge tracking should be continued beyond the FOV of COR2 images. Therefore, heliospheric imager (HI1) data that covers 1590 Rs FOV must be included. In this paper, we propose a novel automatic method that takes both COR2 and HI1 images into account and combine the results to track the front edges of a CME continuously. The method consists of two modules: pre-processing and tracking. The pre-processing module produces a set of segmented images, which contain the signature of a CME, for both COR2 and HI1 separately. In addition, the HI1 images are resized and padded, so that the center of the Sun is the central coordinate of the resized HI1 images. The resulting COR2 andHI1 image set is then fed into the tracking module to estimate the position angle (PA) and track the front edge of a CME. The detected front edge is then used to produce a height-time profile that is used to estimate the speed of a CME. The method was validated using 15 CME events observed in the period from January 1, 2008 to August 31, 2009. The results demonstrate that the proposed method is effective for CME front edge tracking in both COR2 and HI1 images. Using this method, the CME front edge can now be tracked automatically and continuously in a much larger range, i.e., from 2 to 90 Rs, for the first time. These improvement scan greatly

  19. Dual-task performance involving hand dexterity and cognitive tasks and daily functioning in people with schizophrenia: a pilot study.

    Science.gov (United States)

    Lin, Keh-chung; Wu, Yi-fang; Chen, I-chen; Tsai, Pei-luen; Wu, Ching-yi; Chen, Chia-ling

    2015-01-01

    This study investigated separate and concurrent performance on cognitive and hand dexterity tasks and the relationship to daily functioning in 16 people with schizophrenia and 16 healthy control participants. Participants performed the Purdue Pegboard Test and the Serial Seven Subtraction Test under single- and dual-task conditions and completed two daily functioning evaluations. The hand dexterity of all participants declined in the dual-task condition, but the discrepancy between single-task and dual-task hand dexterity was greater in the schizophrenia group than in the control group (p.70, for all). The extent of discrepancy in hand dexterity was negatively correlated with daily functioning in the schizophrenia group (rs=-.3 to -.5, ps=.04-.26). Ability to perform dual tasks may be an indicator of daily functioning in people with schizophrenia. Use of dual-task training may be considered as a therapeutic activity with these clients. Copyright © 2015 by the American Occupational Therapy Association, Inc.

  20. Optimal grasp planning for a dexterous robotic hand using the volume of a generalized force ellipsoid during accepted flattening

    Directory of Open Access Journals (Sweden)

    Peng Jia

    2017-01-01

    Full Text Available A grasp planning method based on the volume and flattening of a generalized force ellipsoid is proposed to improve the grasping ability of a dexterous robotic hand. First, according to the general solution of joint torques for a dexterous robotic hand, a grasping indicator for the dexterous hand—the maximum volume of a generalized external force ellipsoid and the minimum volume of a generalized contact internal force ellipsoid during accepted flattening—is proposed. Second, an optimal grasp planning method based on a task is established using the grasping indicator as an objective function. Finally, a simulation analysis and grasping experiment are performed. Results show that when the grasping experiment is conducted with the grasping configuration and positions of contact points optimized using the proposed grasping indicator, the root-mean-square values of the joint torques and contact internal forces of the dexterous hand are at a minimum. The effectiveness of the proposed grasping planning method is thus demonstrated.

  1. Isolated persistent left-sided superior vena cava, giant coronary sinus, atrial tachycardia and heart failure in a child

    Directory of Open Access Journals (Sweden)

    Nagaraja Moorthy

    2013-09-01

    Full Text Available Persistence of a left-sided superior vena cava (PLSVC with absent right superior vena cava (isolated PLSVC is a very rare venous malformation and commonly associated with congenital heart disease or alterations of the cardiac situs. We describe an unusual case of a young boy presenting with persistent atrial tachycardia and congestive heart failure. He was detected to have unexplained grossly dilated right atrium, right ventricle with systolic dysfunction and a giant coronary sinus (CS. The dilated CS closely mimicked a pseudo cor-triatriatum on echocardiography. Contrast echocardiography from both arms revealed opacification of the CS before the right atrium. Bilateral upper limb venography confirmed the presence of absent right SVC and isolated persistent left SVC draining into the giant coronary sinus.

  2. Persistent left superior vena cava: a case report and review of literature

    Directory of Open Access Journals (Sweden)

    Verma Gita

    2008-10-01

    Full Text Available Abstract Persistent left superior vena cava is rare but important congenital vascular anomaly. It results when the left superior cardinal vein caudal to the innominate vein fails to regress. It is most commonly observed in isolation but can be associated with other cardiovascular abnormalities including atrial septal defect, bicuspid aortic valve, coarctation of aorta, coronary sinus ostial atresia, and cor triatriatum. The presence of PLSVC can render access to the right side of heart challenging via the left subclavian approach, which is a common site of access utilized when placing pacemakers and Swan-Ganz catheters. Incidental notation of a dilated coronary sinus on echocardiography should raise the suspicion of PLSVC. The diagnosis should be confirmed by saline contrast echocardiography.

  3. GNSS Positioning by CORS and EGM2008 in Jilin Province, China

    Directory of Open Access Journals (Sweden)

    Qiong Wu

    2015-12-01

    Full Text Available The Continuously Operating Reference Station (CORS technique has been widely applied in land resource management, surveying, mapping, deformation monitoring, precise navigation, etc. This article analyzed the positioning method using EGM2008 and CORS of Jilin Province, China. The vertical transformation of EGM2008 from WGS84 to China’s CGCS2000 datum and the horizontal coordinate transformation from CGCS2000 to a triangulation coordinate system were discussed. The results indicated that a local geoid with respect to CGCS2000 can be transferred from EGM2008 with the same accuracy, and the geoid correction between CGCS2000 and WGS84 varied from 0.023 m to 0.111 m. The coordinate transformation method based on the curve surface approximation method indicated that the theoretical error was less than 0.09 m in the grid within 10° longitudinal and 5° latitudinal, and less than 0.3 m in large area and 0.1 m in small area in field validation. The method proposed in this article expanded the positioning result and its application for JLCORS and other CORS with local datum.

  4. Exciton broadening and band renormalization due to Dexter-like intervalley coupling

    Science.gov (United States)

    Bernal-Villamil, Ivan; Berghäuser, Gunnar; Selig, Malte; Niehues, Iris; Schmidt, Robert; Schneider, Robert; Tonndorf, Philipp; Erhart, Paul; Michaelis de Vasconcellos, Steffen; Bratschitsch, Rudolf; Knorr, Andreas; Malic, Ermin

    2018-04-01

    A remarkable property of atomically thin transition metal dichalcogenides (TMDs) is the possibility to selectively address single valleys by circularly polarized light. In the context of technological applications, it is very important to understand possible intervalley coupling mechanisms. Here, we show how the Dexter-like intervalley coupling mixes A and B states from opposite valleys leading to a significant broadening γB_{1s} of the B1s exciton. The effect is much more pronounced in tungsten-based TMDs, where the coupling excitonic states are quasi-resonant. We calculate a ratio γB_{1s}/γA_{1s}≈ 4.0 , which is in good agreement with the experimentally measured value of 3.9+/-0.7 . In addition to the broadening effect, the Dexter-like intervalley coupling also leads to a considerable energy renormalization resulting in an increased energetic distance between A1s and B1s states.

  5. EthoHand: A dexterous robotic hand with ball-joint thumb enables complex in-hand object manipulation

    OpenAIRE

    Konnaris, C; Gavriel, C; Thomik, AAC; Aldo Faisal, A

    2016-01-01

    Our dexterous hand is a fundmanetal human feature that distinguishes us from other animals by enabling us to go beyond grasping to support sophisticated in-hand object manipulation. Our aim was the design of a dexterous anthropomorphic robotic hand that matches the human hand's 24 degrees of freedom, under-actuated by seven motors. With the ability to replicate human hand movements in a naturalistic manner including in-hand object manipulation. Therefore, we focused on the development of a no...

  6. NASA Astrophysics Cosmic Origins (COR) and Physics of the Cosmos (PCOS) Strategic Technology Development Program

    Science.gov (United States)

    Pham, Thai; Seery, Bernard D.

    2015-01-01

    The COR and PCOS Program Offices (PO) reside at the NASA Goddard Space Flight Center (GSFC), serving as the NASA Astrophysics Division's implementation arm for matters relating to the two programs. One aspect of the PO's activities is managing the COR and PCOS Strategic Astrophysics Technology (SAT) program, helping mature technologies to enable and enhance future astrophysics missions.The PO is guided by the National Research Council's 'New Worlds, New Horizons in Astronomy and Astrophysics' Decadal Survey report, and NASA's Astrophysics Implementation Plan. Strategic goals include dark energy; gravitational waves; X-ray observatories, e.g., US participation in ATHENA; Inflation probe; and a large UV/Visible telescope.To date, 51 COR and 65 PCOS SAT proposals have been received, of which 11 COR and 18 PCOS projects were funded. Notable successes include maturation of a new far-IR detector, later adopted by the SOFIA HAWC instrument; maturation of the H4RG near-IR detector, adopted by WFIRST; development of an antenna-coupled transition-edge superconducting bolometer, a technology deployed by BICEP2 that allowed measurement of B-mode polarization in the CMB signal, a possible signature of Inflation; and finally, the REXIS instrument on OSIRIS-REx is incorporating CCDs with directly deposited optical blocking filters developed by another SAT-funded project.We discuss our technology development process, with community input and strategic prioritization informing calls for SAT proposals and guiding investment decisions. We also present results of this year's technology gap prioritization and showcase our current portfolio of technology development projects. These include five newly selected projects, kicking off in FY 2015.For more information, visit the COR Program website at cor.gsfc.nasa.gov and the PCOS website at pcos.gsfc.nasa.gov.

  7. National Geospatial Data Asset (NGDA) Continuously Operating Reference Stations (CORS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Geodetic Survey (NGS), an office of NOAA's National Ocean Service, manages a network of Continuously Operating Reference Stations (CORS) that provide...

  8. Modeling Dexterity Development in 2nd-4th-grade Boys by Means of Active Games

    Directory of Open Access Journals (Sweden)

    C. Марченко

    2017-06-01

    Full Text Available The objective is to optimize the mode of using game for dexterity development in the 2nd-4th-grade boys. Materials & methods: to conduct the experiment, there were eight test groups (n=48 formed in each class. The total number of such test groups was 24. The research relied on the following methods: theoretical analysis and collation of scientific and methodological literature; pedagogical testing; methods of mathematical experiment planning (complete factorial experiment 23; modeling method. Results: the research has determined that to develop dexterity, the 2nd-4th-grade boys need to participate in up to five games. The number of repetitions for the 2nd-3rd-graders is two, and for the 4th-graders – three, with 30–40-second rest intervals. The 2nd-4th-grade boys showed effective development during 40 classes, and the 3rd-grade boys – during 20 classes. After that, we recommend to use other means. The game duration varies from one to two minutes. Conclusions: the analysis of the scientific and methodological literature has revealed that the level of motor readiness, dexterity being one of its main components, largely determines the state of children’s physical and mental health. The research has found that the natural development of coordination abilities in boys aged between 7 and 10 is 22.5–80.0% (56.2% on average. Game actions play a particular role in dexterity development in junior schoolers. The 23 complete factorial experiment made it possible to study the multi-factorial structure of game load for the 2nd-4th-graders; to specify the relations between factors for their use during dexterity development in the 2nd-4th-grade boys in physical education classes. They can serve as an objective tool for the educational process optimization. The given regression equations are models that can be used to determine the optimal game means ratio in the academic process of the 2nd-4th-graders.

  9. CorA, the magnesium/nickel/cobalt transporter, affects virulence and extracellular enzyme production in the soft rot pathogen Pectobacterium carotovorum.

    Science.gov (United States)

    Kersey, Caleb M; Agyemang, Paul A; Dumenyo, C Korsi

    2012-01-01

    Pectobacterium carotovorum (formerly Erwinia carotovora ssp. carotovora) is a phytopathogenic bacterium that causes soft rot disease, characterized by water-soaked soft decay, resulting from the action of cell wall-degrading exoenzymes secreted by the pathogen. Virulence in soft rot bacteria is regulated by environmental factors, host and bacterial chemical signals, and a network of global and gene-specific bacterial regulators. We isolated a mini-Tn5 mutant of P. carotovorum that is reduced in the production of extracellular pectate lyase, protease, polygalacturonase and cellulase. The mutant is also decreased in virulence as it macerates less host tissues than its parent and is severely impaired in multiplication in planta. The inactivated gene responsible for the reduced virulent phenotype was identified as corA. CorA, a magnesium/nickel/cobalt membrane transporter, is the primary magnesium transporter for many bacteria. Compared with the parent, the CorA(-) mutant is cobalt resistant. The mutant phenotype was confirmed in parental strain P. carotovorum by marker exchange inactivation of corA. A functional corA(+) DNA from P. carotovorum restored exoenzyme production and pathogenicity to the mutants. The P. carotovorum corA(+) clone also restored motility and cobalt sensitivity to a CorA(-) mutant of Salmonella enterica. These data indicate that CorA is required for exoenzyme production and virulence in P. carotovorum. © 2011 THE AUTHORS. MOLECULAR PLANT PATHOLOGY © 2011 BSPP AND BLACKWELL PUBLISHING LTD.

  10. The Effect of Simultaneous Superficial and Proprioceptive Stimulations on Dexterity of Educable 6-7 Years Old Children with Down Syndrome

    Directory of Open Access Journals (Sweden)

    Meisam Mohammadi

    2011-04-01

    Full Text Available Objectives: Down syndrome is the most common chrosomal disorder in which the fine and gross motor skills due to lack of proper sensory experience are disturbed. The role of dexterity in activity of daily living, interaction with environment and independency is quiet crucial in Down syndrome. Therefore, the aim of this study was to investigate the effects of simultaneous application of superficial and proprioceptive stimuli on the dexterity of 6-7 year-old educable children with Down syndrome. Methods: Thirty–three educable children with Down syndrome were assigned in three groups (i.e. superficial, proprioceptive and simultaneous application respectively and voluntarily participated in the study. In the first group, children received only exteroceptive stimulation for 30 minutes, three times a week. Children in the second group received only proprioceptive stimulation in the same way. In the third group, children received both stimulations simultaneously. Dexterity was evaluated through Purdue Pegbourd Test after 5th, 10th, 15th, 20th, 25th, and 30th sessions. Results: Dexterity changes were significantly differed in all three groups (P0.05. Discussion: The findings of current study suggest that simultaneous application of superficial and proprioceptive senses could be used for improvement the dexterity in children with Down syndrome.

  11. LEFT VENTRICULAR DYSFUNCTION IN COPD WITH OR WITHOUT COR PULMONALE

    Directory of Open Access Journals (Sweden)

    Uma Shankar Mishra

    2018-01-01

    Full Text Available BACKGROUND Chronic Obstructive Pulmonary Disease (COPD is a disease state characterised by the presence of airflow obstruction due to chronic bronchitis or emphysema, which is progressive and partially reversible. Right ventricular failure (cor pulmonale is a well-known complication of COPD. But, it also involves left ventricle leading to systolic as well as diastolic dysfunction, which maybe present with associated RV failure and also as a separate entity. Diastolic dysfunction is due to defective filling of the left ventricle because of the hyperinflated lung. On the other hand, systolic dysfunction maybe secondary to RV failure due to the effects of hypoxia in the cardiac muscle fibres as a part of the systemic hypoxaemia or it may be due to the effects of the circulatory inflammatory mediators leading to atherosclerosis and ischaemia of cardiac muscles. MATERIALS AND METHODS It was a prospective study of 100 patients of COPD classified according to GOLD criteria with or without cor pulmonale admitted to our hospital in the period of January 2014 to October 2015 meeting our inclusion and exclusion criteria. Investigations like chest x-ray, spirometry, 2D-echocardiography and electrocardiography were done and data was collected. Data were pooled and interpreted using standard statistical methods. RESULTS Prevalence of COPD was common after middle age, the peak being around 5th and 6 th decade of life without much gender inequality. Cor pulmonale was found in 65% patients of COPD, of which more number were in the severe COPD. LV systolic dysfunction was found in 44% of all COPD patients and LV diastolic dysfunction was found in 59% of cases. LV diastolic dysfunction was found in 64% and LV systolic dysfunction was found in 49% of patients of COPD with cor pulmonale. LV systolic dysfunction was found in 62% of COPD patients who showed a resting hypoxaemia (SpO2 <90%. CONCLUSION In our study of 100 COPD patients, we found LV diastolic dysfunction

  12. Resonant electronic excitation energy transfer by Dexter mechanism in the quantum dot system

    Science.gov (United States)

    Samosvat, D. M.; Chikalova-Luzina, O. P.; Vyatkin, V. M.; Zegrya, G. G.

    2016-11-01

    In present work the energy transfer between quantum dots by the exchange (Dexter) mechanism is analysed. The interdot Coulomb interaction is taken into consideration. It is assumed that the quantum dot-donor and the quantum dot-acceptor are made from the same compound A3B5 and embedded in the matrix of other material creating potential barriers for electron and holes. The dependences of the energy transfer rate on the quantum-dot system parameters are found using the Kane model that provides the most adequate description spectra of semiconductors A3B5. Numerical calculations show that the rate of the energy transfer by Dexter mechanism is comparable to the rate of the energy transfer by electrostatic mechanism at the distances approaching to the contact ones.

  13. A redundant, 6-DOF parallel manipulator structure with improved workspace and dexterity

    International Nuclear Information System (INIS)

    Stoughton, R.S.; Salerno, R.; Canfield, S.; Reinholtz, C.

    1994-08-01

    This paper presents a novel manipulator structure which combines two known parallel manipulator structures--a Stewart Platform (SP), and a double octahedral Variable Geometry Truss (VGT). The combined VGT + SP structure is redundant, using nine actuators to realize six-DOF motion. Combining the two structures allows the translational and orientational workspaces of the two individual structures to sum together to a much larger workspace than is generally achievable with parallel manipulator structures. In addition, the VGT portion of the structure allows the configuration of the Stewart Platform to be changed ''on the fly'' from one with a large workspace to one with high dexterity. A useful application of this structure is at the distal end of a truss-based manipulator, where it can serve as a dexterous wrist while preserving an internal passageway for cabling and/or conveyance systems

  14. Signatures of Förster and Dexter transfer processes in coupled nanostructures for linear and two-dimensional coherent optical spectroscopy

    Science.gov (United States)

    Specht, Judith F.; Richter, Marten

    2015-03-01

    In this manuscript, we study the impact of the two Coulomb induced resonance energy transfer processes, Förster and Dexter coupling, on the spectral signatures obtained by double quantum coherence spectroscopy. We show that the specific coupling characteristics allow us to identify the underlying excitation transfer mechanism by means of specific signatures in coherent spectroscopy. Therefore, we control the microscopic calculated coupling strength of spin preserving and spin flipping Förster transfer processes by varying the mutual orientation of the two quantum emitters. The calculated spectra reveal the optical selection rules altered by Förster and Dexter coupling between two semiconductor quantum dots. We show that Dexter coupling between bright and dark two-exciton states occurs.

  15. A Dexterity and Tactility Evaluation of the Australian Nuclear Biological Chemical (NBC) Glove

    National Research Council Canada - National Science Library

    Scanlan, S

    2004-01-01

    This report details the tactility and dexterity of four different glove types, including the Australian in-service NBC butyl rubber glove and Nomex flying glove for standardized (Purdue pegboard) and operational...

  16. The precise regulation of different COR genes by individual CBF transcription factors in Arabidopsis thaliana.

    Science.gov (United States)

    Shi, Yihao; Huang, Jiaying; Sun, Tianshu; Wang, Xuefei; Zhu, Chenqi; Ai, Yuxi; Gu, Hongya

    2017-02-01

    The transcription factors CBF1/2/3 are reported to play a dominant role in the cold responsive network of Arabidopsis by directly regulating the expression levels of cold responsive (COR) genes. In this study, we obtained CRISPR/Cas9-mediated loss-of-function mutants of cbf1∼3. Over 3,000 COR genes identified by RNA-seq analysis showed a slight but significant change in their expression levels in the mutants compared to the wild-type plants after being treated at 4 °C for 12 h. The C-repeat (CRT) motif (5'-CCGAC-3') was enriched in promoters of genes that were up-regulated by CBF2 and CBF3 but not in promoters of genes up-regulated by CBF1. These data suggest that CBF2 and CBF3 play a more important role in directing the cold response by regulating different sets of downstream COR genes. More than 2/3 of COR genes were co-regulated by two or three CBFs and were involved mainly in cellular signal transduction and metabolic processes; less than 1/3 of the genes were regulated by one CBF, and those genes up-regulated were enriched in cold-related abiotic stress responses. Our results indicate that CBFs play an important role in the trade-off between cold tolerance and plant growth through the precise regulation of COR genes in the complicated transcriptional network. © 2016 The Authors. Journal of Integrative Plant Biology Published by John Wiley & Sons Australia, Ltd on behalf of Institute of Botany, Chinese Academy of Sciences.

  17. the effect of heterosexual contact on libido and mating dexterity in ...

    African Journals Online (AJOL)

    stages of sexual development on adult behaviour are avail- able. Consequently. the present experiment was executed to determine the effects of total isolation as well as that of heterosexual contact during the pre· -and post-puberal phase on libido, mating dexterity and the occurrence of homosexuality in Karakul rams.

  18. Automatic near-real-time detection of CMEs in Mauna Loa K-Cor coronagraph images

    Science.gov (United States)

    Thompson, W. T.; St Cyr, O. C.; Burkepile, J.; Posner, A.

    2017-12-01

    A simple algorithm has been developed to detect the onset of coronal massejections (CMEs), together with an estimate of their speed, in near-real-timeusing images of the linearly polarized white-light solar corona taken by theK-Cor telescope at the Mauna Loa Solar Observatory (MLSO). The algorithm usedis a variation on the Solar Eruptive Event Detection System (SEEDS) developedat George Mason University. The algorithm was tested against K-Cor data takenbetween 29 April 2014 and 20 February 2017, on days which the MLSO websitemarked as containing CMEs. This resulted in testing of 139 days worth of datacontaining 171 CMEs. The detection rate varied from close to 80% in 2014-2015when solar activity was high, down to as low as 20-30% in 2017 when activitywas low. The difference in effectiveness with solar cycle is attributed to thedifference in relative prevalance of strong CMEs between active and quietperiods. There were also twelve false detections during this time period,leading to an average false detection rate of 8.6% on any given day. However,half of the false detections were clustered into two short periods of a fewdays each when special conditions prevailed to increase the false detectionrate. The K-Cor data were also compared with major Solar Energetic Particle(SEP) storms during this time period. There were three SEP events detectedeither at Earth or at one of the two STEREO spacecraft where K-Cor wasobserving during the relevant time period. The K-Cor CME detection algorithmsuccessfully generated alerts for two of these events, with lead times of 1-3hours before the SEP onset at 1 AU. The third event was not detected by theautomatic algorithm because of the unusually broad width of the CME in positionangle.

  19. Resonant electronic excitation energy transfer by Dexter mechanism in the quantum dot system

    International Nuclear Information System (INIS)

    Samosvat, D M; Chikalova-Luzina, O P; Zegrya, G G; Vyatkin, V M

    2016-01-01

    In present work the energy transfer between quantum dots by the exchange (Dexter) mechanism is analysed. The interdot Coulomb interaction is taken into consideration. It is assumed that the quantum dot-donor and the quantum dot-acceptor are made from the same compound A3B5 and embedded in the matrix of other material creating potential barriers for electron and holes. The dependences of the energy transfer rate on the quantum-dot system parameters are found using the Kane model that provides the most adequate description spectra of semiconductors A3B5. Numerical calculations show that the rate of the energy transfer by Dexter mechanism is comparable to the rate of the energy transfer by electrostatic mechanism at the distances approaching to the contact ones. (paper)

  20. Comparison of Lyman-alpha and LI-COR infrared hygrometers for airborne measurement of turbulent fluctuations of water vapour

    Science.gov (United States)

    Lampert, Astrid; Hartmann, Jörg; Pätzold, Falk; Lobitz, Lennart; Hecker, Peter; Kohnert, Katrin; Larmanou, Eric; Serafimovich, Andrei; Sachs, Torsten

    2018-05-01

    To investigate if the LI-COR humidity sensor can be used as a replacement of the Lyman-alpha sensor for airborne applications, the measurement data of the Lyman-alpha and several LI-COR sensors are analysed in direct intercomparison flights on different airborne platforms. One vibration isolated closed-path and two non-isolated open-path LI-COR sensors were installed on a Dornier 128 twin engine turbo-prop aircraft. The closed-path sensor provided absolute values and fluctuations of the water vapour mixing ratio in good agreement with the Lyman-alpha. The signals of the two open-path sensors showed considerable high-frequency noise, and the absolute value of the mixing ratio was observed to drift with time in this vibrational environment. On the helicopter-towed sensor system Helipod, with very low vibration levels, the open-path LI-COR sensor agreed very well with the Lyman-alpha sensor over the entire frequency range up to 3 Hz. The results show that the LI-COR sensors are well suited for airborne measurements of humidity fluctuations, provided that a vibrationless environment is given, and this turns out to be more important than close sensor spacing.

  1. Dexter Time: The Space, Time, and Matterings of School Absence Registration

    Science.gov (United States)

    Bodén, Linnea

    2016-01-01

    Working with a posthumanist approach, this article explores how the computer software Dexter, used for the registration of students' absences and presences, is part of the production of different practices of time, place, space, and matter in Swedish schools. The empirical material engaged with comes from two schools, and the students involved are…

  2. CORS911:Real-Time Subsidence Monitoring of the Napoleonville Salt Dome Sinkhole Using GPS

    Science.gov (United States)

    Kent, J. D.

    2013-12-01

    The sinkhole associated with the Napoleonville salt dome in Assumption Parish, Louisiana, threatens the stability of Highway 70 - a state maintained route. To mitigate the potential damaging effects to the highway and address issues of public safety, a program of research and decision support has been implemented to provide long-term measurements of the surface stability using continuous operating GPS reference stations (CORS). Four CORS sites were installed in the vicinity of the sinkhole to measure the horizontal and vertical motions of each site relative to each other and a fixed location outside the study area. Differential motions measured by a integrity monitoring software are summarized for response agencies tasked with ensuring public safety and stability of the Highway, a designated hurricane evacuation route. Implementation experience and intermediate findings will be shared and discussed. Strategies for monitoring random and systematic biases detected in the system are presented. Figure depicting the location of CORS sites used to monitor surface stability along Highway 70 near the Bayou Corne Sinkhole.

  3. Combined long reach and dexterous manipulation for waste storage tank applications

    International Nuclear Information System (INIS)

    Burks, B.L.; Armstrong, G.A.; Butler, P.L.; Boissiere, P.

    1991-01-01

    One of the highest priority environmental restoration tasks within the Department of Energy (DOE) is the remediation of single-shell waste storage tanks (WSTs), especially those suspected of, or documented as, leakers. Most currently proposed approaches for remediation of large underground WSTs require application of remotely operated long-reach (greater than 10 m), high-lift capacity (greater than 200 kg) manipulator systems. Because of the complexity of in-tank hardware, waste forms, remediation tasks, and variety of end-effector tools, these manipulator systems must also be capable of performing a diverse set of dexterous manipulations. This presentation will describe the integration of a Spar RMS 2500 manipulator system, a Schilling Titan-7F manipulator, and control systems developed at ORNL and SNL to provide a combined long reach and dexterous manipulation system. The purpose of integrating these two manipulator systems was to study and demonstrate their combined performance, evaluate design requirements for a deployed system, and provide a testbed for control and end-effector technologies that might be applicable to remediation of WSTs. 5 refs

  4. Manual dexterity in hereditary motor and sensory neuropathy type 1a: severity of limitations and feasibility and reliability of two assessment instruments

    NARCIS (Netherlands)

    Videler, Annemieke J.; Beelen, Anita; van Schaik, Ivo N.; de Visser, Marianne; Nollet, Frans

    2008-01-01

    OBJECTIVE: To assess the prevalence and significance of impaired manual dexterity in hereditary motor and sensory neuropathy type 1a (HMSN 1a), with the Sollerman hand function and the Functional Dexterity test, and compare the reliability and agreement of the tests. DESIGN: Descriptive

  5. Suppressing effect of COR659 on alcohol, sucrose, and chocolate self-administration in rats: involvement of the GABAB and cannabinoid CB1 receptors.

    Science.gov (United States)

    Maccioni, Paola; Colombo, Giancarlo; Lorrai, Irene; Zaru, Alessandro; Carai, Mauro A M; Gessa, Gian Luigi; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico

    2017-09-01

    COR659 [methyl2-(4-chlorophenylcarboxamido)-4-ethyl-5-methylthiophene-3-carboxylate] is a new, positive allosteric modulator (PAM) of the GABA B receptor. This study evaluated whether COR659 shared with previously tested GABA B PAMs the capacity to reduce alcohol self-administration in rats. Treatment with non-sedative doses of COR659 (2.5, 5, and 10 mg/kg; i.p.) suppressed lever-responding for alcohol (15% v/v) in Sardinian alcohol-preferring (sP) rats under the fixed ratio (FR) 4 (FR4) and progressive ratio (PR) schedules of reinforcement; COR659 was more potent and effective than the reference GABA B PAM, GS39783. Treatment with COR659, but not GS39783, suppressed (a) lever-responding for a sucrose solution (1-3% w/v) in sP rats under the FR4 and PR schedules, (b) lever-responding for a chocolate solution [5% (w/v) Nesquik®] in Wistar rats under the FR10 and PR schedules, and (c) cue-induced reinstatement of chocolate seeking in Wistar rats. Treatment with COR659 was completely ineffective on lever-responding (FR10) for regular food pellets in food-deprived Wistar rats. Pretreatment with the GABA B receptor antagonist, SCH50911, partially blocked COR659-induced reduction of alcohol self-administration, being ineffective on reduction of chocolate self-administration. Pretreatment with the cannabinoid CB 1 receptor antagonist, AM4113, fully blocked COR659-induced reduction of chocolate self-administration, being ineffective on reduction of alcohol self-administration. COR659 might exert its behavioral effects via a composite mechanism: (i) positive allosteric modulation of the GABA B receptor, responsible for a large proportion of reduction of alcohol self-administration; (ii) an action at other receptor system(s), including the cannabinoid CB 1 receptor, through which COR659 affects seeking and consumption of highly palatable foods.

  6. Cor a 14 is the superior serological marker for hazelnut allergy in children, independent of concomitant peanut allergy

    DEFF Research Database (Denmark)

    Eller, Esben; Mortz, Charlotte G; Bindslev-Jensen, Carsten

    2016-01-01

    BACKGROUND: Hazelnut is the most frequent cause of tree-nut allergy, but up to half of all children with hazelnut allergy additionally suffers from peanut allergy. Our aim was to identify diagnostic values of the most promising serological markers (Cor a 9 and Cor a 14) and to address the influence...... of concomitant peanut allergy and PR10 sensitization. METHOD: We included 155 children suspected off hazelnut allergy and challenged according to guidelines. Concomitant allergy to peanuts was verified or ruled out by challenge. Skin Prick Test, s-IgE and CRD to hazelnut, peanut, PR10 and LPT protein families...... were measured using ImmunoCap. RESULTS: Sixty-five children had a positive hazelnut challenge, and 60% of these also had concomitant peanut allergy. Children allergic to hazelnut were sensitized to Cor a 9 and Cor a 14; peanut allergic children to Ara h 2. Sensitization to PR10 protein components were...

  7. Rehab-let: touchscreen tablet for self-training impaired dexterity post stroke: study protocol for a pilot randomized controlled trial.

    Science.gov (United States)

    Rand, Debbie; Zeilig, Gabi; Kizony, Rachel

    2015-06-18

    Impaired dexterity of the weaker upper extremity is common post stroke and it is recommended that these individuals practice many repetitions of movement to regain function. However, stroke rehabilitation methods do not achieve the required intensity to be effective. Touchscreen tablet technology may be used as a motivating tool for self-training impaired dexterity of the weaker upper extremity post stroke. Rehab-let is a self-training protocol utilizing game apps on a touchscreen for practicing movement of the weaker upper extremity. We will conduct a pilot randomized controlled trial to assess Rehab-let compared to traditional self-training to improve dexterity of the weaker hand, and to increase self-training time and satisfaction in individuals with subacute stroke. Forty individuals with stroke undergoing subacute rehabilitation will be randomly allocated to Rehab-let or a traditional self-training program using therapeutic aids such as balls, blocks and pegs. All participants will be requested to perform self-training for 60 minutes a day, 5 times a week for 4 weeks. Dexterity assessed by The Nine Hole Peg Test is the main outcome measure. Assessments will be administered pre and post the self-training intervention by assessors blind to the group allocation. The outcomes of this study will inform the design of a fully powered randomized controlled trial to evaluate the effectiveness of Rehab-let. If found to be effective, Rehab-let can be used during subacute rehabilitation to increase treatment intensity and improve dexterity. Potentially, Rehab-let can also be used after discharge and might be ideal for individuals with mild stroke who are often not referred to formal rehabilitation. Current Controlled Trials NCT02136433 registered on 17 September 2014.

  8. Electromyogram synergy control of a dexterous artificial hand to unscrew and screw objects.

    Science.gov (United States)

    Kent, Benjamin A; Karnati, Nareen; Engeberg, Erik D

    2014-03-21

    Due to their limited dexterity, it is currently not possible to use a commercially available prosthetic hand to unscrew or screw objects without using elbow and shoulder movements. For these tasks, prosthetic hands function like a wrench, which is unnatural and limits their use in tight working environments. Results from timed rotational tasks with human subjects demonstrate the clinical need for increased dexterity of prosthetic hands, and a clinically viable solution to this problem is presented for an anthropomorphic artificial hand. Initially, a human hand motion analysis was performed during a rotational task. From these data, human hand synergies were derived and mapped to an anthropomorphic artificial hand. The synergy for the artificial hand is controlled using conventional dual site electromyogram (EMG) signals. These EMG signals were mapped to the developed synergy to control four joints of the dexterous artificial hand simultaneously.Five limb absent and ten able-bodied test subjects participated in a comparison study to complete a timed rotational task as quickly as possible with their natural hands (except for one subject with a bilateral hand absence), eight commercially available prosthetic hands, and the proposed synergy controller. Each test subject used two to four different artificial hands. With the able-bodied subjects, the developed synergy controller reduced task completion time by 177% on average. The limb absent subjects completed the task faster on average than with their own prostheses by 46%. There was a statistically significant improvement in task completion time with the synergy controller for three of the four limb absent participants with integrated prostheses, and was not statistically different for the fourth. The proposed synergy controller reduced average task completion time compared to commercially available prostheses. Additionally, the synergy controller is able to function in a small workspace and requires less physical

  9. Local vibration inhibits H-reflex but does not compromise manual dexterity and does not increase tremor.

    Science.gov (United States)

    Budini, Francesco; Laudani, Luca; Bernardini, Sergio; Macaluso, Andrea

    2017-10-01

    The present work aimed at investigating the effects of local vibration on upper limb postural and kinetic tremor, on manual dexterity and on spinal reflex excitability. Previous studies have demonstrated a decrease in spinal reflex excitability and in force fluctuations in the lower limb but an increase in force fluctuation in the upper limbs. As hand steadiness is of vital importance in many daily-based tasks, and local vibration may also be applied in movement disorders, we decided to further explore this phenomenon. Ten healthy volunteers (26±3years) were tested for H reflex, postural and kinetic tremor and manual dexterity through a Purdue test. EMG was recorded from flexor carpi radialis (FCR) and extensor digitorum communis (EDC). Measurements were repeated at baseline, after a control period during which no vibration was delivered and after vibration. Intervention consisted in holding for two minutes a vibrating handle (frequency 75Hz, displacement∼7mm), control consisted in holding for two minutes the same handle powered off. Reflex excitability decreased after vibration whilst postural tremor and manual dexterity were not affected. Peak kinetic tremor frequency increased from baseline to control measurements (P=0.002). Co-activation EDC/FCR increased from control to vibration (P=0.021). These results show that two minutes local vibration lead to a decrease in spinal excitability, did not compromise manual dexterity and did not increase tremor; however, in contrast with expectations, tremor did not decrease. It is suggested that vibration activated several mechanisms with opposite effects, which resulted in a neutral outcome on postural and kinetic tremor. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Control Framework for Dexterous Manipulation Using Dynamic Visual Servoing and Tactile Sensors’ Feedback

    Directory of Open Access Journals (Sweden)

    Carlos A. Jara

    2014-01-01

    Full Text Available Tactile sensors play an important role in robotics manipulation to perform dexterous and complex tasks. This paper presents a novel control framework to perform dexterous manipulation with multi-fingered robotic hands using feedback data from tactile and visual sensors. This control framework permits the definition of new visual controllers which allow the path tracking of the object motion taking into account both the dynamics model of the robot hand and the grasping force of the fingertips under a hybrid control scheme. In addition, the proposed general method employs optimal control to obtain the desired behaviour in the joint space of the fingers based on an indicated cost function which determines how the control effort is distributed over the joints of the robotic hand. Finally, authors show experimental verifications on a real robotic manipulation system for some of the controllers derived from the control framework.

  11. Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar

    OpenAIRE

    Gabriela Soncini Pasetto; Henrique Pedroso de Freitas; Carina Graziottin Colossi; Manuel Augusto Pereira Vilela

    2013-01-01

    OBJETIVO: Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide. MÉTODOS: Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento. RESULTADOS: De um total de 18 olhos, 7 (38.9%) foram incluídos no estudo. ...

  12. Design and implementation of a dexterous anthropomorphic robotic typing (DART) hand

    International Nuclear Information System (INIS)

    Thayer, Nicholas; Priya, Shashank

    2011-01-01

    This paper focuses on design and implementation of a biomimetic dexterous humanoid hand. Several design rules are proposed to retain human form and functionality in a robotic hand while overcoming the difficultly of actuation within a confined geometry. Size and weight have been optimized in order to achieve human-like performance with the prime objective of typing on a computer keyboard. Each finger has four joints and three degrees of freedom (DOF) while the thumb has an additional degree of freedom necessary for manipulating small objects. The hand consists of 16 servo motors dedicated to finger motion and three motors for wrist motion. A closed-loop kinematic control scheme utilizing the Denavit–Hartenberg convention for spatial joint positioning was implemented. Servo motors housed in the forearm act as an origin for wires to travel to their insertion points in the hand. The dexterity of the DART hand was measured by quantifying functionality and typing speed on a standard keyboard. The typing speed of a single DART hand was found to be 20 words min −1 . In comparison, the average human has a typing speed of 33 words min −1 with two hands

  13. Phylo_dCor: distance correlation as a novel metric for phylogenetic profiling.

    Science.gov (United States)

    Sferra, Gabriella; Fratini, Federica; Ponzi, Marta; Pizzi, Elisabetta

    2017-09-05

    Elaboration of powerful methods to predict functional and/or physical protein-protein interactions from genome sequence is one of the main tasks in the post-genomic era. Phylogenetic profiling allows the prediction of protein-protein interactions at a whole genome level in both Prokaryotes and Eukaryotes. For this reason it is considered one of the most promising methods. Here, we propose an improvement of phylogenetic profiling that enables handling of large genomic datasets and infer global protein-protein interactions. This method uses the distance correlation as a new measure of phylogenetic profile similarity. We constructed robust reference sets and developed Phylo-dCor, a parallelized version of the algorithm for calculating the distance correlation that makes it applicable to large genomic data. Using Saccharomyces cerevisiae and Escherichia coli genome datasets, we showed that Phylo-dCor outperforms phylogenetic profiling methods previously described based on the mutual information and Pearson's correlation as measures of profile similarity. In this work, we constructed and assessed robust reference sets and propose the distance correlation as a measure for comparing phylogenetic profiles. To make it applicable to large genomic data, we developed Phylo-dCor, a parallelized version of the algorithm for calculating the distance correlation. Two R scripts that can be run on a wide range of machines are available upon request.

  14. Primair sarcoom van de A. pulmonalis : zeldzame oorzaak van cor pulmonale

    NARCIS (Netherlands)

    Ismaël, F; van der Werf, T S; de Boer, W J; Timens, W; Nossent, G D; Ligtenberg, J J

    1999-01-01

    A 64-year-old female presented with fever and weight loss, accompanied by normochromic normocytic anaemia with high erythrocyte sedimentation rate. She developed severe cor pulmonale. Ventilation-perfusion scintigraphy revealed a non-matched perfusion defect of the entire right lung with impaired

  15. The New England Journal of Medicine, CorSalud and Cardiovascular Disease The New England Journal of Medicine, CorSalud y las enfermedades cardiovasculares

    Directory of Open Access Journals (Sweden)

    Francisco Luis Moreno Martínez

    2012-03-01

    Full Text Available In order to commemorate the 200th anniversary of The New England Journal of Medicine, the working staff of CorSalud extends its congratulations to this prestigious medical journal. It has been demonstrated the important role this journal played by increasing scientific knowledge, specifically in the specialty of Cardiology and,of course, its editorial quality, based not only on experience but also on professionalism. All this places it as a paradigm to be followed by each and all of the journals in the medical and scientific community.Con motivo del aniversario 200 de The New England Journal of Medicine, el colectivo de CorSalud hace llegar su felicitación a esa prestigiosa publicación médica. Queda manifiesto el importante papel que ha tenido esa revista en el incremento del conocimiento científico, específicamente en la especialidad de Cardiología; y desde luego, su calidad editorial, basadas no solo en experiencia sino también en profesionalismo, la sitúan como paradigma a seguir por todas y cada una de las revistas de la comunidad científica médica.

  16. Integrating clinical performance improvement across physician organizations: the PhyCor experience.

    Science.gov (United States)

    Loeppke, R; Howell, J W

    1999-02-01

    There is a paucity of literature describing the implementation of clinical performance improvement (CPI) efforts across geographically dispersed multispecialty group practices and independent practice associations. PhyCor, a physician management company based in Nashville, Tennessee, has integrated CPI initiatives into its operating infrastructure. PhyCor CPI INITIATIVES: The strategic framework guiding PhyCor's CPI initiatives is built around a physician-driven, patient-centered model. Physician/administrator leadership teams develop and implement a clinical and financial strategic plan for performance improvement; adopt local clinical and operational performance indicators; and agree on and gain consensus with local physician champions to engage in CPI initiatives. The area/regional leadership councils integrate and coordinate regional medical management and CPI initiatives among local groups and independent practice associations. In addition to these councils and a national leadership council, condition-specific care management councils have also been established. These councils develop condition-specific protocols and outcome measures and lead the implementation of CPI initiatives at their own clinics. Key resources supporting CPI initiatives include information/knowledge management, education and training, and patient education and consumer decision support. Localized efforts in both the asthma care and diabetes management initiatives have led to some preliminary improvements in quality of care indicators. Physician leadership and strategic vision, CPI-oriented organizational infrastructure, broad-based physician involvement in CPI, providing access to performance data, parallel incentives, and creating a sense of urgency for accelerated change are all critical success factors to the implementation of CPI strategies at the local, regional, and national levels.

  17. Internal and external cooling methods and their effect on body temperature, thermal perception and dexterity.

    Directory of Open Access Journals (Sweden)

    Matthew J Maley

    Full Text Available The present study aimed to compare a range of cooling methods possibly utilised by occupational workers, focusing on their effect on body temperature, perception and manual dexterity.Ten male participants completed eight trials involving 30 min of seated rest followed by 30 min of cooling or control of no cooling (CON (34°C, 58% relative humidity. The cooling methods utilised were: ice cooling vest (CV0, phase change cooling vest melting at 14°C (CV14, evaporative cooling vest (CVEV, arm immersion in 10°C water (AI, portable water-perfused suit (WPS, heliox inhalation (HE and ice slushy ingestion (SL. Immediately before and after cooling, participants were assessed for fine (Purdue pegboard task and gross (grip and pinch strength manual dexterity. Rectal and skin temperature, as well as thermal sensation and comfort, were monitored throughout.Compared with CON, SL was the only method to reduce rectal temperature (P = 0.012. All externally applied cooling methods reduced skin temperature (P0.05.The present study observed that ice ingestion or ice applied to the skin produced the greatest effect on rectal and skin temperature, respectively. AI should not be utilised if workers require subsequent fine manual dexterity. These results will help inform future studies investigating appropriate pre-cooling methods for the occupational worker.

  18. Chorea: clinical correlates of 119 cases Coréia: análise clínica de 119 casos

    Directory of Open Access Journals (Sweden)

    Maria Fernanda Mendes

    1996-09-01

    Full Text Available Chorea is a clinical syndrome characterized by abnormal involuntary arrhythmic movements, randomly distributed in time, affecting mainly the distal parts of the limbs. There are many diseases associated with chorea but the distribution of the etiologies vary too much in different parts of the world. We intended to study the etiologies of chorea in a Movement Disorders Unit of a university hospital-based outpatient clinic in Brazil. We studied the records of 119 patients with chorea based in the diagnostic criteria of the World Federation of Neurology. Sydenham's chorea (SC was the most frequent cause of chorea (51.3% of our sample. Other common causes were Huntington's chorea (18.5% and chorea post-stroke (9.2%. SC is not commonly seen in developed countries nowadays but is not rare in Brazil. SC patients generally have the clinical manifestation of it in the first 20 years of age and girls are more affected than boys and this feature was observed in our sample. Based on our own experience and in the review of the literature we propose an etiological classification of chorea.Coréia é uma síndrome caracterizada por movimentos involuntários arrítmicos, rápidos, abruptos, não repetitivos no tempo e com distribuição variável, preferentemente distal. O número de entidades clínicas reconhecidamente associadas a movimentos coréicos tem se tornado cada vez maior com o passar do tempo. Propusemo-nos estudar a frequência e algumas características epidemiológicas das coréias atendidas em um ambulatório especializado em distúrbios do movimento. Foram estudados os prontuários de 119 pacientes com o diagnóstico sindrômico de coréia. O predomínio absoluto foi de coréia de Sydenham (CS com 51,3% do total da amostra. Outras causas frequentes foram doença de Huntington (DH presente em 18,5% e a coréia secundária a doença cerebrovascular em 9,2% dos pacientes. O sexo feminino predominou em todas as faixas etárias, mas principalmente

  19. Compact Dexterous Robotic Hand

    Science.gov (United States)

    Lovchik, Christopher Scott (Inventor); Diftler, Myron A. (Inventor)

    2001-01-01

    A compact robotic hand includes a palm housing, a wrist section, and a forearm section. The palm housing supports a plurality of fingers and one or more movable palm members that cooperate with the fingers to grasp and/or release an object. Each flexible finger comprises a plurality of hingedly connected segments, including a proximal segment pivotally connected to the palm housing. The proximal finger segment includes at least one groove defining first and second cam surfaces for engagement with a cable. A plurality of lead screw assemblies each carried by the palm housing are supplied with power from a flexible shaft rotated by an actuator and output linear motion to a cable move a finger. The cable is secured within a respective groove and enables each finger to move between an opened and closed position. A decoupling assembly pivotally connected to a proximal finger segment enables a cable connected thereto to control movement of an intermediate and distal finger segment independent of movement of the proximal finger segment. The dexterous robotic hand closely resembles the function of a human hand yet is light weight and capable of grasping both heavy and light objects with a high degree of precision.

  20. Dexterity test data contribute to proper glovebox over-glove use

    International Nuclear Information System (INIS)

    Cournoyer, Michael E.; Lawton, Cindy M.; Castro, Armanda M.; Costigan, Stephen A.; Apel, D.M.; Neal, G.E.; Castro, J.M.; Michelotti, R.A.

    2010-01-01

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (TA-55) involve working with various amounts of plutonium and other highly toxic, alpha-emitting materials. The spread of radiological contamination on surfaces, airborne contamination, and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes (the glovebox, coupled with an adequate negative pressure gradient, provides primary confinement). The glovebox gloves are the weakest part of this engineering control. The Glovebox Glove Integrity Program, which controls glovebox gloves from procurement to disposal at TA-55, manages this vulnerability. A key element of this program is to consider measures that lower the overall risk of glovebox operations. Proper selection of over-gloves is one of these measures. Line management owning glovebox processes have the responsibility to approve the appropriate personal protective equipment/glovebox glove/over-glove combination. As low as reasonably achievable (ALARA) considerations to prevent unplanned glovebox glove openings must be balanced with glove durability and worker dexterity, both of which affect the final overall risk to the worker. In this study, the causes of unplanned glovebox glove openings, the benefits of over-glove features, the effect of over-gloves on task performance using standard dexterity tests, the pollution prevention benefits, and the recommended over-gloves for a task are presented.

  1. Tumores de plexo coróide: estudo epidemiológico comparativo de 24 casos

    Directory of Open Access Journals (Sweden)

    Torres Luiz Fernando Bleggi

    2004-01-01

    Full Text Available Tumores derivados do plexo coróide são neoplasias raras do sistema nervoso central que acometem principalmente crianças. Este estudo apresenta uma série de 38 pacientes com tumores de origem neuroectodérmica, dentre os quais 24 possuem diagnóstico histológico e/ou imunoistoquímico de Carcinoma do Plexo Coróide (CPC. Destes, 16 eram do gênero masculino. O local predominantemente acometido foi o ventrículo lateral esquerdo. As manifestações clínicas mais freqüentes foram hidrocefalia, hipertensão intracraniana e crises convulsivas. Todos os pacientes foram submetidos a tratamento cirúrgico. Houve um óbito no per-operatório e outro no pós-operatório imediato. Nove pacientes tiveram recidiva, evoluindo a óbito em tempo médio de 12,3 meses. Sete estão vivos. Os demais casos não apresentavam dados disponíveis. Em Curitiba, o CPC tem uma alta prevalência em relação a outros tumores do plexo coróide, podendo estar relacionado a algum agente patogênico.

  2. Harmonia cromática em animações: a cor no contexto da tecnologia

    OpenAIRE

    Franck, Gláucia

    2015-01-01

    Esta dissertação busca demonstrar a influência recíproca entre a arte e a tecnologia para além do artefato com o uso da cor na obtenção da harmonia cromática e do reforço perceptivo visual e cultural. Procuramos evidenciar como a arte se apropria da tecnologia na obtenção da harmonia pelo uso da cor no processo criativo. A arte, ao ser mediada pela tecnologia, desafia o artista a opor-se ao determinismo tecnológico que impõe resultados pela estandardização do uso de seus aparatos, superando s...

  3. Robotic finger perturbation training improves finger postural steadiness and hand dexterity.

    Science.gov (United States)

    Yoshitake, Yasuhide; Ikeda, Atsutoshi; Shinohara, Minoru

    2018-02-01

    The purpose of the study was to understand the effect of robotic finger perturbation training on steadiness in finger posture and hand dexterity in healthy young adults. A mobile robotic finger training system was designed to have the functions of high-speed mechanical response, two degrees of freedom, and adjustable loading amplitude and direction. Healthy young adults were assigned to one of the three groups: random perturbation training (RPT), constant force training (CFT), and control. Subjects in RPT and CFT performed steady posture training with their index finger using the robot in different modes: random force in RPT and constant force in CFT. After the 2-week intervention period, fluctuations of the index finger posture decreased only in RPT during steady position-matching tasks with an inertial load. Purdue pegboard test score improved also in RPT only. The relative change in finger postural fluctuations was negatively correlated with the relative change in the number of completed pegs in the pegboard test in RPT. The results indicate that finger posture training with random mechanical perturbations of varying amplitudes and directions of force is effective in improving finger postural steadiness and hand dexterity in healthy young adults. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Compromised Motor Dexterity Confounds Processing Speed Task Outcomes in Stroke Patients

    Directory of Open Access Journals (Sweden)

    Essie Low

    2017-09-01

    Full Text Available Most conventional measures of information processing speed require motor responses to facilitate performance. However, although not often addressed clinically, motor impairment, whether due to age or acquired brain injury, would be expected to confound the outcome measure of such tasks. The current study recruited 29 patients (20 stroke and 9 transient ischemic attack with documented reduction in dexterity of the dominant hand, and 29 controls, to investigate the extent to which 3 commonly used processing speed measures with varying motor demands (a Visuo-Motor Reaction Time task, and the Wechsler Adult Intelligence Scale-IV Symbol Search and Coding subtests may be measuring motor-related speed more so than cognitive speed. Analyses include correlations between indices of cognitive and motor speed obtained from two other tasks (Inspection Time and Pegboard task, respectively with the three speed measures, followed by hierarchical regressions to determine the relative contribution of cognitive and motor speed indices toward task performance. Results revealed that speed outcomes on tasks with relatively high motor demands, such as Coding, were largely reflecting motor speed in individuals with reduced dominant hand dexterity. Thus, findings indicate the importance of employing measures with minimal motor requirements, especially when the assessment of speed is aimed at understanding cognitive rather than physical function.

  5. Sofrimento psíquico na perversão: o caso dexter

    Directory of Open Access Journals (Sweden)

    Fábio Roberto Rodrigues Belo

    2012-09-01

    Full Text Available A análise do personagem fictício Dexter permite construir hipóteses metapsicológicas sobre as origens da perversão. A posição perversa nesse caso deve-se à presença maciça de violência nas origens do sujeito psíquico. Dexter expressa o abandono sofrido pela atuação pulsional, os assassinatos em série, tentando inverter o estado de passividade no qual se encontra. Sua angústia pode ser organizada de duas formas distintas: a primeira é consciente, fornecida por seu pai, Harry, que o ensina a não deixar vestígios dos seus crimes. A segunda maneira é inconsciente, e traduz o desejo de submeter o outro à dor, fazendo com que, por meio do mecanismo de identificação projetiva, o perverso desfrute deste sofrimento que provoca, sendo remetido, então, às suas vivências originárias de submissão. Conclui-se que na perversão a angústia não apenas está presente, como também é constitutiva da escolha do sujeito de operar pela via da violência.

  6. Two-dimensional spectroscopy: An approach to distinguish Förster and Dexter transfer processes in coupled nanostructures

    Science.gov (United States)

    Specht, Judith F.; Knorr, Andreas; Richter, Marten

    2015-04-01

    The linear and two-dimensional coherent optical spectra of Coulomb-coupled quantum emitters are discussed with respect to the underlying coupling processes. We present a theoretical analysis of the two different resonance energy transfer mechanisms between coupled nanostructures: Förster and Dexter interaction. Our investigation shows that the features visible in optical spectra of coupled quantum dots can be traced back to the nature of the underlying coupling mechanism (Förster or Dexter). Therefore, we discuss how the excitation transfer pathways can be controlled by choosing particular laser polarizations and mutual orientations of the quantum emitters in coherent two-dimensional spectroscopy. In this context, we analyze to what extent the delocalized double-excitonic states are bound to the optical selection rules of the uncoupled system.

  7. Telepresence master glove controller for dexterous robotic end-effectors

    Science.gov (United States)

    Fisher, Scott S.

    1987-01-01

    This paper describes recent research in the Aerospace Human Factors Research Division at NASA's Ames Research Center to develop a glove-like, control and data-recording device (DataGlove) that records and transmits to a host computer in real time, and at appropriate resolution, a numeric data-record of a user's hand/finger shape and dynamics. System configuration and performance specifications are detailed, and current research is discussed investigating its applications in operator control of dexterous robotic end-effectors and for use as a human factors research tool in evaluation of operator hand function requirements and performance in other specialized task environments.

  8. Internal and external cooling methods and their effect on body temperature, thermal perception and dexterity

    Science.gov (United States)

    Minett, Geoffrey M.; Bach, Aaron J. E.; Zietek, Stephanie A.; Stewart, Kelly L.; Stewart, Ian B.

    2018-01-01

    Objective The present study aimed to compare a range of cooling methods possibly utilised by occupational workers, focusing on their effect on body temperature, perception and manual dexterity. Methods Ten male participants completed eight trials involving 30 min of seated rest followed by 30 min of cooling or control of no cooling (CON) (34°C, 58% relative humidity). The cooling methods utilised were: ice cooling vest (CV0), phase change cooling vest melting at 14°C (CV14), evaporative cooling vest (CVEV), arm immersion in 10°C water (AI), portable water-perfused suit (WPS), heliox inhalation (HE) and ice slushy ingestion (SL). Immediately before and after cooling, participants were assessed for fine (Purdue pegboard task) and gross (grip and pinch strength) manual dexterity. Rectal and skin temperature, as well as thermal sensation and comfort, were monitored throughout. Results Compared with CON, SL was the only method to reduce rectal temperature (P = 0.012). All externally applied cooling methods reduced skin temperature (Ptemperature versus other cooling methods. Participants felt cooler with CV0, CV14, WPS, AI and SL (P0.05). Conclusion The present study observed that ice ingestion or ice applied to the skin produced the greatest effect on rectal and skin temperature, respectively. AI should not be utilised if workers require subsequent fine manual dexterity. These results will help inform future studies investigating appropriate pre-cooling methods for the occupational worker. PMID:29357373

  9. Development of the cat-owner relationship scale (CORS).

    Science.gov (United States)

    Howell, Tiffani J; Bowen, Jonathan; Fatjó, Jaume; Calvo, Paula; Holloway, Anna; Bennett, Pauleen C

    2017-08-01

    Characteristics of the human-animal bond can be influenced by both owner-related and pet-related factors, which likely differ between species. Three studies adapted the Monash Dog-Owner Relationship Scale (MDORS) to permit assessment of human-cat interactions as perceived by the cat's owner. In Study 1293 female cat owners completed a modified version of the MDORS, where 'dog' was replaced with 'cat' for all items. Responses were compared with a matched sample of female dog owners. A partial least squares discriminant analysis revealed systematic differences between cat and dog owners in the Dog (Cat)-Owner Interaction subscale (MDORS subscale 1), but not for Perceived Emotional Closeness or Perceived Costs (Subscales 2 and 3). Study 2 involved analysis of free-text descriptions of cat-owner interactions provided by 61 female cat owners. Text mining identified key words which were used to create additional questions for a new Cat-Owner Interaction subscale. In Study 3, the resulting cat-owner relationship scale (CORS) was tested in a group of 570 cat owners. The main psychometric properties of the scale, including internal consistency and factor structure, were evaluated. We propose that this scale can be used to accurately assess owner perceptions of their relationship with their cat. A modified scale, combining items from the CORS and MDORS (a C/DORS), is also provided for when researchers would find it desirable to compare human-cat and human-dog interactions. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. MSR Founding Narratives and Content Analysis of Best/Dexter Award Nominee Papers (2001-2015)

    DEFF Research Database (Denmark)

    Tackney, Charles T.; Chappell, Stacie; Sato, Toyoko

    data and founder interviews. The individuals interviewed were identified through preliminary inquiry and from archival data. As a complement of and extension to this inclusive founding narrative, we conducted a content and discourse analysis of the 15 years of MSR Best Papers and Carolyn Dexter Best...

  11. Preconceito de cor e racismo no Brasil

    OpenAIRE

    Guimarães, Antonio Sérgio Alfredo

    2004-01-01

    O autor analisa a formação do campo temático dos estudos de relações raciais, no Brasil dos anos 1940, e sua posterior superação pelos estudos de identidade racial e racismo, nos anos 1970, buscando precisar a história dos significados teóricos de dois conceitos: preconceito de cor e racismo. Retroagindo ao final do século XIX, o autor argumenta que o racialismo dogmático de então foi desbancado pelo culturalismo do começo do século XX, apenas para ceder lugar à imprecisão entre a expressão n...

  12. Multiobjective Optimum Design of a 3-RRR Spherical Parallel Manipulator with Kinematic and Dynamic Dexterities

    DEFF Research Database (Denmark)

    Wu, Guanglei

    2012-01-01

    parameters of the spherical parallel manipulator. The proposed approach is illustrated with the optimum design of a special spherical parallel manipulator with unlimited rolling motion. The corresponding optimization problem aims to maximize the kinematic and dynamic dexterities over its regular shaped...

  13. Cognitive vision system for control of dexterous prosthetic hands: Experimental evaluation

    Directory of Open Access Journals (Sweden)

    Došen Strahinja

    2010-08-01

    Full Text Available Abstract Background Dexterous prosthetic hands that were developed recently, such as SmartHand and i-LIMB, are highly sophisticated; they have individually controllable fingers and the thumb that is able to abduct/adduct. This flexibility allows implementation of many different grasping strategies, but also requires new control algorithms that can exploit the many degrees of freedom available. The current study presents and tests the operation of a new control method for dexterous prosthetic hands. Methods The central component of the proposed method is an autonomous controller comprising a vision system with rule-based reasoning mounted on a dexterous hand (CyberHand. The controller, termed cognitive vision system (CVS, mimics biological control and generates commands for prehension. The CVS was integrated into a hierarchical control structure: 1 the user triggers the system and controls the orientation of the hand; 2 a high-level controller automatically selects the grasp type and size; and 3 an embedded hand controller implements the selected grasp using closed-loop position/force control. The operation of the control system was tested in 13 healthy subjects who used Cyberhand, attached to the forearm, to grasp and transport 18 objects placed at two different distances. Results The system correctly estimated grasp type and size (nine commands in total in about 84% of the trials. In an additional 6% of the trials, the grasp type and/or size were different from the optimal ones, but they were still good enough for the grasp to be successful. If the control task was simplified by decreasing the number of possible commands, the classification accuracy increased (e.g., 93% for guessing the grasp type only. Conclusions The original outcome of this research is a novel controller empowered by vision and reasoning and capable of high-level analysis (i.e., determining object properties and autonomous decision making (i.e., selecting the grasp type and

  14. DexterNet: An Open Platform for Heterogeneous Body Sensor Networks and Its Applications

    Science.gov (United States)

    2008-12-19

    motion, ECG PC, PDA 802.15.4 No No ALARM-NET pulse oximetry STARGATE Bluetooth No Yes [19] motion, ECG PDA, PC 802.11 (temperature, light, PIR) DexterNet...motion, ECG PDA 802.15.4 Yes Possible via SPINE EIP, GPS PC (e.g., air pollution sensor) MICAz, SHIMMER uses MICAz sensors and STARGATE to relay the

  15. Strength and fine dexterity recovery profiles after a primary motor cortex insult and effect of a neuronal cell graft.

    Science.gov (United States)

    Vaysse, Laurence; Conchou, Fabrice; Demain, Boris; Davoust, Carole; Plas, Benjamin; Ruggieri, Cyrielle; Benkaddour, Mehdi; Simonetta-Moreau, Marion; Loubinoux, Isabelle

    2015-08-01

    The aim of this study was to set up (a) a large primary motor cortex (M1) lesion in rodent and (b) the conditions for evaluating a long-lasting motor deficit in order to propose a valid model to test neuronal replacement therapies aimed at improving motor deficit recovery. A mitochondrial toxin, malonate, was injected to induce extensive destruction of the forelimb M1 cortex. Three key motor functions that are usually evaluated following cerebral lesion in the clinic-strength, target reaching, and fine dexterity-were assessed in rats by 2 tests, a forelimb grip strength test and a skilled reaching task (staircase) for reaching and dexterity. The potential enhancement of postlesion recovery induced by a neuronal cell transplantation was then explored and confirmed by histological analyses. Both tests showed a severe functional impairment 2 days post lesion, however, reaching remained intact. Deficits in forelimb strength were long lasting (up to 3 months) but spontaneously recovered despite the extensive lesion size. This natural grip strength recovery could be enhanced by cell therapy. Histological analyses confirmed the presence of grafted cells 3 months postgraft and showed partial tissue reconstruction with some living neuronal cells in the graft. In contrast, fine dexterity never recovered in the staircase test even after grafting. These results suggest that cell replacement was only partially effective and that the forelimb M1 area may be a node of the sensorimotor network, where compensation from secondary pathways could account for strength recovery but recovery of forelimb fine dexterity requires extensive tissue reconstruction. (c) 2015 APA, all rights reserved).

  16. Molding resonant energy transfer by colloidal crystal: Dexter transfer and electroluminescence

    Science.gov (United States)

    González-Urbina, Luis; Kolaric, Branko; Libaers, Wim; Clays, Koen

    2010-05-01

    Building photonic crystals by combination of colloidal ordering and metal sputtering we were able to construct a system sensitive to an electrical field. In corresponding crystals we embedded the Dexter pair (Ir(ppy3) and BAlq) and investigated the influence of the band gap on the resonant energy transfer when the system is excited by light and by an electric field respectively. Our investigations extend applications of photonic crystals into the field of electroluminescence and LED technologies.

  17. StreptInCor: a candidate vaccine epitope against S. pyogenes infections induces protection in outbred mice.

    Directory of Open Access Journals (Sweden)

    Edilberto Postol

    Full Text Available Infection with Streptococcus pyogenes (S. pyogenes can result in several diseases, particularly in children. S. pyogenes M protein is the major virulence factor, and certain regions of its N-terminus can trigger autoimmune sequelae such as rheumatic fever in susceptible individuals with untreated group A streptococcal pharyngitis. In a previous study, we utilized a large panel of human peripheral blood cells to define the C-terminal protective epitope StreptInCor (medical identity, which does not induce autoimmune reactions. We recently confirmed the results in HLA-transgenic mice. In the present study, we extended the experimental assays to outbred animals (Swiss mice. Herein, we demonstrate high titers of StreptInCor-specific antibodies, as well as appropriate T-cell immune responses. No cross-reaction to cardiac myosin was detected. Additionally, immunized Swiss mice exhibited 87% survival one month after challenge with S. pyogenes. In conclusion, the data presented herein reinforce previous results in humans and animals and further emphasize that StreptInCor could be an effective and safe vaccine for the prevention of S. pyogenes infections.

  18. InsCor: um método simples e acurado para avaliação do risco em cirurgia cardíaca

    Directory of Open Access Journals (Sweden)

    Omar A. V. Mejía

    2013-03-01

    Full Text Available FUNDAMENTO: Escores de risco apresentam dificuldades para obter o mesmo desempenho em diferentes populações. OBJETIVO: Criar um modelo simples e acurado para avaliação do risco nos pacientes operados de doença coronariana e/ou valvar no Instituto do Coração da Universidade de São Paulo (InCor-HCFMUSP. MÉTODOS: Entre 2007 e 2009, 3.000 pacientes foram operados consecutivamente de doença coronariana e/ou valvar no InCor-HCFMUSP. Desse registro, dados de 2/3 dos pacientes foram utilizados para desenvolvimento do modelo (técnica de bootstrap e de 1/3 para validação interna do modelo. O desempenho do modelo (InsCor foi comparado aos complexos 2000 Bernstein-Parsonnet (2000BP e EuroSCORE (ES. RESULTADOS: Apenas 10 variáveis foram selecionadas: Idade > 70 anos; sexo feminino; cirurgia de revascularização coronariana + valva; infarto de miocárdio < 90 dias; reoperação; tratamento cirúrgico da valva aórtica; tratamento cirúrgico da valva tricúspide; creatinina < 2mg/dL; fração de ejeção < 30%; e eventos. O teste de Hosmer Lemeshow para o InsCor foi de 0,184, indicando uma excelente calibração. A área abaixo da curva ROC foi de 0,79 para o InsCor, 0,81 para o ES e 0,82 para o 2000BP, confirmando que os modelos são bons e similares na discriminação. CONCLUSÕES: O InsCor e o ES tiveram melhor desempenho que o 2000BP em todas as fases da validação; pórem o novo modelo, além de se identificar com os fatores de risco locais, é mais simples e objetivo para a predição de mortalidade nos pacientes operados de doença coronariana e/ou valvar no InCor-HCFMUSP.

  19. MoveBots - Flexible Object Handling using Dexterous Grippers

    DEFF Research Database (Denmark)

    Jørgensen, Jimmy Alison

    .This dissertation present work that focus on increasing flexibility ofrobotic grasping by using simulation tools, dexterous hands and tactile sensors.The work is centered on development of tools and methods for graspplanning, analysis and simulation.Overall the research contributes with valuable tools......Within recent years there has been an increased focus in flexible automationin industrial production. This focus is strongly related to the demandfor small product batches and individually customized products. To enablesuch flexibility large machinery is exchanged or upgraded with high degreeof...... freedom robot manipulators. These manipulators are programmable andmultipurpose and often only limited by their gripper systems. These limitationsare significant since the design and flexibility of the gripper determineswhich objects the system can handle.Current gripper systems are typically simple...

  20. A Subcortical Oscillatory Network Contributes to Recovery of Hand Dexterity after Spinal Cord Injury

    Science.gov (United States)

    Nishimura, Yukio; Morichika, Yosuke; Isa, Tadashi

    2009-01-01

    Recent studies have shown that after partial spinal-cord lesion at the mid-cervical segment, the remaining pathways compensate for restoring finger dexterity; however, how they control hand/arm muscles has remained unclear. To elucidate the changes in dynamic properties of neural circuits connecting the motor cortex and hand/arm muscles, we…

  1. Effects of repeated vibratory stimulation of wrist and elbow flexors on hand dexterity, strength, and sensory function in patients with chronic stroke: a pilot study.

    Science.gov (United States)

    Choi, Won-Ho

    2017-04-01

    [Purpose] The aim of this study was to investigate the effects of repeated vibratory stimulation to muscles related to hand functions on dexterity, strength, and sensory function in patients with chronic stroke. [Subjects and Methods] A total of 10 stroke patients with hemiplegia participated in this study. They were divided into two groups: a) Experimental and b) Control, with five randomly selected subjects for each group. The experimental group received vibratory stimulation, while the control group received the traditional physical therapy. Both interventions were performed for 30 minutes each session, three times a week for four weeks. [Results] There was a significant within-group improvement in the box and block test results in both groups for dexterity. Grip strength improved in both groups but the improvement was not statistically significant. [Conclusion] The vibratory stimulation activated the biceps brachii and flexor carpi radialis, which increased dexterity to grasp and lift the box and block from the surface. Therefore, repeated vibratory stimulation to muscles related to hand functions improved hand dexterity equality to the traditional physical therapy in patients with chronic stroke.

  2. Small intestinal absorption in patients with chronic obstructive pulmonary disease complicated by cor pulmonale - A pilot study

    DEFF Research Database (Denmark)

    Andersen, Sara Korsgaard; Hardis, Anne L S; Tupper, Oliver Djurhuus

    2018-01-01

    BACKGROUND: Cor pulmonale is a common complication to Chronic Obstructive Pulmonary Disease (COPD), and may result in increased pressure in the inferior caval vein and stasis of the liver. The chronic pulmonary hypertension may lead to stasis in the veins from the small intestine and thereby...... compromise absorption of nutrients. AIM: To investigate whether patients with pulmonary hypertension have reduced absorption capacity compared to COPD patients without cor pulmonale. METHODS: Absorption of d-xylose (25 g) and zinc (132 mg), administered as a single dose, was tested in 14 COPD patients, seven...

  3. Synthesis of dexterity measure of mechanisms by evolution of dissipative system

    Directory of Open Access Journals (Sweden)

    Grešl M.

    2007-11-01

    Full Text Available The paper deals with the new approach of solving traditional kinematical synthesis of mechanisms. The kinematical synthesis is reformulated as nonlinear dynamical problem. All searched parameters of the mechanism are in this dynamical dissipative system introduced as time-varying during motion of mechanism’s dimension iteration. The synthesis process is realized as the time evolution of such system. One of the most important objectives of the machine synthesis is the dexterity measure. The new approach is applied to optimization of this property.

  4. Bangladesh Norms for a Gender-Specific Functional Fine Dexterity Test (FFDT

    Directory of Open Access Journals (Sweden)

    Debra K. Lindstrom-Hazel

    2016-10-01

    Full Text Available Background: Good psychometrics and cultural relevance are needed for evidence-based practice. Occupational therapy (OT assessment tools in Bangladesh have been developed outside of Bangladesh and have not been validated or normed for Bangladeshis. This normative and psychometric study was to provide culturally relevant norms for in Bangladesh for bilateral fine motor. Method: The Functional Fine Dexterity Test (FFDT consists of two functional/self-care gender-specific task instruments: a shirt with five buttons for males and a pinning board for females. Raters were trained in timing these tasks. Results: Intra-Class Correlation (ICC scores were > .85 for all rater teams. Participants were timed three times while they completed the task. Convergent validity was examined using a Pearson’s Product-Moment correlation to compare the average of three trials of the FFDT and three trials of the Nine Hole Peg Test (NHPT. Male and female norms were developed for the FFDT using descriptive statistics. The sample included 180 Bangladesh participants. Convergent validity, when compared to the NHPT, ranged from r = .4 to .67 for males (ages 18-29 and 40-49, p < .05; and r = .53 to .76 for females (aged 18-39, p < .05. FFDT norms were developed for gender and age categories. Conclusion: The FFDT is a valid test to use for evaluating fine motor dexterity in Bangladesh. This is the first OT instrument to be studied for culturally relevancy.

  5. Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways.

    Science.gov (United States)

    Sancho, Rosa M; Law, Bernard M H; Harvey, Kirsten

    2009-10-15

    Mutations in PARK8, encoding LRRK2, are the most common known cause of Parkinson's disease. The LRRK2 Roc-COR tandem domain exhibits GTPase activity controlling LRRK2 kinase activity via an intramolecular process. We report the interaction of LRRK2 with the dishevelled family of phosphoproteins (DVL1-3), key regulators of Wnt (Wingless/Int) signalling pathways important for axon guidance, synapse formation and neuronal maintenance. Interestingly, DVLs can interact with and mediate the activation of small GTPases with structural similarity to the LRRK2 Roc domain. The LRRK2 Roc-COR domain and the DVL1 DEP domain were necessary and sufficient for LRRK2-DVL1 interaction. Co-expression of DVL1 increased LRRK2 steady-state protein levels, an effect that was dependent on the DEP domain. Strikingly, LRRK2-DVL1-3 interactions were disrupted by the familial PARK8 mutation Y1699C, whereas pathogenic mutations at residues R1441 and R1728 strengthened LRRK2-DVL1 interactions. Co-expression of DVL1 with LRRK2 in mammalian cells resulted in the redistribution of LRRK2 to typical cytoplasmic DVL1 aggregates in HEK293 and SH-SY5Y cells and co-localization in neurites and growth cones of differentiated dopaminergic SH-SY5Y cells. This is the first report of the modulation of a key LRRK2-accessory protein interaction by PARK8 Roc-COR domain mutations segregating with Parkinson's disease. Since the DVL1 DEP domain is known to be involved in the regulation of small GTPases, we propose that: (i) DVLs may influence LRRK2 GTPase activity, and (ii) Roc-COR domain mutations modulating LRRK2-DVL interactions indirectly influence kinase activity. Our findings also link LRRK2 to Wnt signalling pathways, suggesting novel pathogenic mechanisms and new targets for genetic analysis in Parkinson's disease.

  6. Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar

    Directory of Open Access Journals (Sweden)

    Gabriela Soncini Pasetto

    2013-08-01

    Full Text Available OBJETIVO: Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide. MÉTODOS: Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento. RESULTADOS: De um total de 18 olhos, 7 (38.9% foram incluídos no estudo. Cinco (71,4% pacientes foram tratados exclusivamente com termoterapia transpupilar, em 1 (14,2% olho a crioterapia foi simultânea, 1 (14,2% suplementou braquiterapia - placa episcleral. Três (42.8% sofreram recorrência, 2 (28.5% apresentaram metástases (um óbito, 2 foram enucleados. Complicações foram encontradas em 3 olhos: dobras maculares em 2, hemorragia vítrea em 1. Nos olhos enucleados, não havia extensão extraescleral, porém células interesclerais foram identificadas. CONCLUSÃO: Termoterapia transpupilar mostra um declínio em sua eficácia e conserva os riscos de metástases em períodos mais longos de acompanhamento, sendo necessária uma definição mais exata de seu papel nos melanomas de coróide.

  7. Independent trapping and manipulation of microparticles using dexterous acoustic tweezers

    International Nuclear Information System (INIS)

    Courtney, Charles R. P.; Demore, Christine E. M.; Wu, Hongxiao; Cochran, Sandy; Grinenko, Alon; Wilcox, Paul D.; Drinkwater, Bruce W.

    2014-01-01

    An electronically controlled acoustic tweezer was used to demonstrate two acoustic manipulation phenomena: superposition of Bessel functions to allow independent manipulation of multiple particles and the use of higher-order Bessel functions to trap particles in larger regions than is possible with first-order traps. The acoustic tweezers consist of a circular 64-element ultrasonic array operating at 2.35 MHz which generates ultrasonic pressure fields in a millimeter-scale fluid-filled chamber. The manipulation capabilities were demonstrated experimentally with 45 and 90-μm-diameter polystyrene spheres. These capabilities bring the dexterity of acoustic tweezers substantially closer to that of optical tweezers

  8. Clinical assessment of the efficacy of SpineCor brace in the correction of postural deformities in the course of idiopathic scoliosis.

    Science.gov (United States)

    Plewka, Barbara; Sibiński, Marcin; Synder, Marek; Witoński, Dariusz; Kołodziejczyk-Klimek, Katarzyna; Plewka, Michał

    2013-03-26

    The objective of the study was to perform a clinical, comparative assessment of the degree of postural deformities before and after the treatment of idiopathic scoliosis in patients treated with SpineCor brace compared to the control group. A group of 90 children with idiopathic scoliosis (including 74 girls) at the average age of 12.2 was subject to prospective observation. Average pre-treatment Cobb angle was 24.9° in the thoracic spine and 25.8° in the lumbar spine. The group actively treated with the SpineCor brace consisted of 45 children, while the control group consisted of the remaining 45 children with the natural course of the disease. Both groups did not differ significantly in terms of age, gender, height, body weight, Risser sign of skeletal maturity and baseline clinical and radiological parameters of scoliosis. Significant reduction of rib hump was observed upon 2-year SpineCor brace treatment (P=0.04) compared to the group treated by physiotherapy only (P=0.91). Similarly, improvement in lumbar prominence was observed in the actively treated group (P=0.009), with a trend towards worse results in the control group (P=0.07) In the group treated with the SpineCor brace, significant reduction in pectoral and hamstring muscle contractures as well as reduction in shoulder asymmetry and reduction in anterior and posterior vertical deviation were observed. Treatment using the SpineCor dynamic brace leads to a clinical improvement in posture, particularly to reduction in rib hump, lumbar prominence and muscular contractures.

  9. Central aortic blood pressure and augmentation index: comparison between Vasotens® and SphygmoCor® technology

    Directory of Open Access Journals (Sweden)

    Rogoza AN

    2012-05-01

    Full Text Available Anatoliy N Rogoza,1 Aleksandr A Kuznetsov21Cardiology Research Complex, Moscow, Russian Federation; 2Therapy Research Institute, Siberian branch of Russian Academy of Medical Science, Novosibirsk, Russian FederationIntroduction: The aim of this study is the comparison of Vasotens® technology as used in a device with an oscillometric method of blood pressure measurement (BPLab, Petr Telegin Ltd, Nizhny Novgorod, Russian Federation against the validated tonometric system (SphygmoCor®, AtCor Medical Pty Ltd, West Ryde, Australia.Methods: The examinations were carried out in two medical centers. Exclusion criteria included atrial fibrillation, severe cardiac anomalies, heart failure, arrhythmia, decompensated diabetes, the presence of an artificial pacemaker, pregnancy, and BMI > 30. Overall, 160 patients and healthy volunteers were examined. Central aortic systolic blood pressure (aSBP and augmentation index (aAIx were obtained by means of applanation tonometry and the oscillometric method was compared.Results: aSBP and aAIx measured using the BPLab device equates significantly with the same parameters measured by SphygmoCor.Conclusion: This finding allows the recommendation of Vasotens technology, which can be used with the 24-hour BPLab monitoring system for wide clinical use.Keywords: central aortic blood pressure, augmentation index, validation, Vasotens®, BPLab®

  10. Performance of InsCor and three international scores in cardiac surgery at Santa Casa de Marília.

    Science.gov (United States)

    Tiveron, Marcos Gradim; Bomfim, Helton Augusto; Simplício, Maycon Soto; Bergonso, Marcos Henriques; Matos, Milena Paiva Brasil de; Ferreira, Sergio Marques; Pelloso, Eraldo Antônio; Barros, Rubens Tofano de

    2015-01-01

    To apply and to compare the Society of Thoracic Surgery score (STS), EuroSCORE (Eurosc1), EuroSCORE II (Eurosc2) and InsCor (IS) for predicting mortality in patients undergoing to coronary artery bypass graft and/or valve surgery at the Santa Casa Marilia. The present study is a cohort. It is a prospective, observational, analytical and unicentric. We analyzed 562 consecutive patients coronary artery bypass graft and/or valve surgery, between April 2011 and June 2013 at the Santa Casa Marilia. Mortality was calculated for each patient through the scores STS, Eurosc1, Eurosc2 and IS. The calibration was calculated using the Hosmer Lemeshow test and discrimination by ROC curve. The hospital mortality was 4,6%. The calibration is generally adequate group P=0.345, P=0.765, P=0.272 and P=0.062 for STS, Eurosc1, Eurosc2, and IS respectively. The discriminatory power of STS score 0.649 (95% CI 0.529 to 0.770, P=0.012), Eurosc1 0.706 (95% CI 0.589 to 0.823, P ≤0.001), Eurosc2 was 0.704 (95% CI 0.590-0.818 P=0.001) and InsCor 0.739 (95% CI 0.638 to 0.839, P ≤0.001). We can say that overall, the InsCor was the best model, mainly in the discrimination of the sample. The InsCor showed good accuracy, in addition to being effective and easy to apply, especially by using a smaller number of variables compared to the other models.

  11. Pulmonary embolism and cor pulmonale in a cat

    International Nuclear Information System (INIS)

    Sottiaux, J.; Franck, M.

    1999-01-01

    A 14-year-old male neutered cat experienced pulmonary embolism 15 days following surgical debridement of a recurrent dorsolumbar abscess. Clinical signs were dominated by respiratory distress. Pulmonary embolism was suggested from the lateral thoracic radiograph by the presence of an abruptly attenuated lobar artery and a contiguous oligaemic area in the caudal lung lobe. Pulmonary hypertension was demonstrated on Doppler echocardiography by right pulmonary artery dilation and tricuspid regurgitation raising the pulmonary arterial pressure to 56 mmHg. Chronic pulmonary hypertension, assumed from right ventricular wall hypertrophy, and hypokinesia, indicating chronic cor pulmonale, was suggestive of chronic rather than acute pulmonary embolism. Postmortem histological evidence of pulmonary arteriolar occlusion confirmed the diagnosis of pulmonary embolism

  12. The clinical significance of determination of adrenal medulla in patients with chronic cor pulmonale and analysis of its relevant factors

    International Nuclear Information System (INIS)

    Tian Yingchun; Zha Jinshun

    2002-01-01

    In order to find the function of adrenal medulla in the development of chronic cor pulmonale and the effect of smoking, anoxia and lung's work on adrenal medulla, the authors determined adrenal medulla in 63 patients with acute cor pulmonale (Group A) and 60 controls (Group B). The authors tried to find out the effect of the patients' age, course of disease, history of smoking, malfunction of lung on adrenal medulla by multiple regressive analysis. Adrenal medulla is significantly higher in Group A than that of in Group B (P 2 both contribute to the conclusion that smoking is an independent factor to affect the adrenal medulla. The study shows that the adrenal medulla in patients with cor pulmonale is higher than that of normal people, and that the level of adrenal medulla is dependent on the degree of seriousness of the disease, obstructive ventilatory disturbance and anoxia

  13. Usability of videogame-based dexterity training in the early rehabilitation phase of stroke patients : A pilot study

    NARCIS (Netherlands)

    Vanbellingen, Tim; Filius, Suzanne J.; Nyffeler, Thomas; van Wegen, Erwin E.H.

    2017-01-01

    Background: Approximately 70-80% of stroke survivors have limited activities of daily living, mainly due to dexterous problems. Videogame-based training (VBT) along with virtual reality seems to be beneficial to train upper limb function. Objective: To evaluate the usability of VBT using the Leap

  14. Physical Demand but Not Dexterity Is Associated with Motor Flexibility during Rapid Reaching in Healthy Young Adults

    NARCIS (Netherlands)

    Greve, Christian; Hortobagyi, Tibor; Bongers, Raoul M.

    2015-01-01

    Healthy humans are able to place light and heavy objects in small and large target locations with remarkable accuracy. Here we examine how dexterity demand and physical demand affect flexibility in joint coordination and end-effector kinematics when healthy young adults perform an upper extremity

  15. Contribution of GNSS CORS Infrastructure to the Mission of Modern Geodesy and Status of GNSS CORS in Thailand

    Directory of Open Access Journals (Sweden)

    Chalermchon Satirapod

    2011-01-01

    Full Text Available Geodesy is the science of measuring and mapping the geometry, orientation and gravity field of the Earth including the associated variations with time. Geodesy has also provided the foundation for high accuracy surveying and mapping. Modern Geodesy involves a range of space and terrestrial technologies that contribute to our knowledge of the solid earth, atmosphere and oceans. These technologies include: Global Positioning System/Global Navigation Satellite Systems (GPS/GNSS, Satellite Laser Ranging (SLR, Very Long Baseline Interferometry (VLBI, Satellite Altimetry, Gravity Mapping Missions such as GRACE, CHAMP and GOCE, satelliteborne Differential Interferometric Synthetic Aperture Radar (DInSAR, Absolute and Relative Gravimetry, and Precise Terrestrial Surveying (Levelling and Traversing. A variety of services have been established in recent years to ensure high accuracy and reliable geodetic products to support geoscientific research. The reference frame defined by Modern Geodesy is now the basis for most national and regional datums. Furthermore, the GPS/GNSS technology is a crucial geopositioning tool for both Geodesy and Surveying. There is therefore a blurring of the distinction between geodetic and surveying GPS/GNSS techniques, and increasingly the ground infrastructure of continuously operating reference stations (CORS receivers attempts to address the needs of both geodesists and other positioning professionals. Yet Geodesy is also striving to increase the level of accuracy by a factor of ten over the next decade in order to address the demands of “global change” studies. The Global Geodetic Observing System (GGOS is an important component of the International Association of Geodesy. GGOS aims to integrate all geodetic observations in order to generate a consistent high quality set of geodetic parameters for monitoring the phenomena and processes within the “System Earth”. Integration implies the inclusion of all relevant

  16. A prospective randomized controlled study on the treatment outcome of SpineCor brace versus rigid brace for adolescent idiopathic scoliosis with follow-up according to the SRS standardized criteria.

    Science.gov (United States)

    Guo, Jing; Lam, Tsz Ping; Wong, Man Sang; Ng, Bobby Kin Wah; Lee, Kwong Man; Liu, King Lok; Hung, Lik Hang; Lau, Ajax Hong Yin; Sin, Sai Wing; Kwok, Wing Kwan; Yu, Fiona Wai Ping; Qiu, Yong; Cheng, Jack Chun Yiu

    2014-12-01

    SpineCor is a relatively innovative brace for non-operative treatment of adolescent idiopathic scoliosis (AIS). However, the effectiveness of SpineCor still remains controversial. The objective of the current study was to compare the treatment outcomes of SpineCor brace with that of rigid brace following the standardized Scoliosis Research Society (SRS) criteria on AIS brace study. Females subjects with AIS and aged 10-14 were randomly allocated into two groups undergoing treatment of SpineCor (S Group, n = 20) or rigid brace (R Group, n = 18). During SpineCor treatment, patients who had curve progression of >5° would be required to switch to rigid brace treatment. The effectiveness of the two brace treatments was assessed using the SRS standardized criteria. Before skeletal maturity, 7 (35.0%) patients in the S Group and 1 (5.6%) patient in the R Group had curve progression >5° (P = 0.026). At skeletal maturity, 5 of the 7 (71.4%) patients who failed with SpineCor bracing showed control from further progression by changing to rigid bracing. At the latest follow-up with a mean duration of 45.1 months after skeletally maturity, 29.4% of patients who were successfully treated by rigid brace showed further curve progression beyond skeletal maturity, versus 38.5% of patients in the SpineCor group (P > 0.05). For both groups, the primary curves were slightly improved at the time of brace weaning, but additionally increased at the latest follow-up, with a rate of 1.5° per year for post-maturity progression. Curve progression rate was found to be significantly higher in the SpineCor group when compared with the rigid brace group. Changing to rigid bracing could control further curve progression for majority of patients who previously failed with SpineCor bracing. For both SpineCor and rigid brace treatments, 30-40% of patients who were originally successfully treated by bracing would exhibit further curve progression beyond skeletal maturity. The post

  17. A cor da dor: iniquidades raciais na atenção pré-natal e ao parto no Brasil

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Leal

    Full Text Available Poucas pesquisas com foco nas influências da raça/cor no tocante à experiência de gestação e parto foram conduzidas no Brasil, sendo inédita a análise de abrangência nacional. Este estudo teve como objetivo avaliar as iniquidades na atenção pré-natal e parto de acordo com a raça/cor utilizando o método de pareamento baseado nos escores de propensão. Os dados são oriundos da pesquisa Nascer no Brasil: Pesquisa Nacional sobre Parto e Nascimento, um estudo de base populacional de abrangência nacional com entrevista e avaliação de prontuários de 23.894 mulheres em 2011/2012. Regressões logísticas simples foram utilizadas para estimar as razões de chance (OR e respectivos intervalos de 95% de confiança (IC95% da raça/cor associada aos desfechos analisados. Em comparação às brancas, puérperas de cor preta possuíram maior risco de terem um pré-natal inadequado (OR = 1,6; IC95%: 1,4-1,9, falta de vinculação à maternidade (OR = 1,2; IC95%: 1,1-1,4, ausência de acompanhante (OR = 1,7; IC95%: 1,4-2,0, peregrinação para o parto (OR = 1,3; IC95%: 1,2-1,5 e menos anestesia local para episiotomia (OR = 1,5 (IC95%: 1,1-2,1. Puérperas de cor parda também tiveram maior risco de terem um pré-natal inadequado (OR = 1,2; IC95%: 1,1-1,4 e ausência de acompanhante (OR = 1,4; IC95%: 1,3-1,6 quando comparadas às brancas. Foram identificadas disparidades raciais no processo de atenção à gestação e ao parto evidenciando um gradiente de pior para melhor cuidado entre mulheres pretas, pardas e brancas.

  18. Review: Lewis A. Dexter (2006. Elite and Specialized Interviewing. With a New Introduction by Alan Ware and Martín Sánchez-Jankowski

    Directory of Open Access Journals (Sweden)

    Beate Littig

    2008-01-01

    Full Text Available The European Consortium for Political Research (ECPR republished in 2006 the book of the political scientist L.A. DEXTER on "Elite and Specialized Interviewing." According to DEXTER the main characteristic of this type of interviews is non-standardized treatment. Through this the interviewee is given the chance to present his or her own relevance with regard to the topic and situation at stake. What seems to be self-evident in the context of qualitative social research today—the importance of the interviewee's definition of the situation and the topic at stake—can be regarded as an innovation in the 1970ies considering the predominance of quantitative social research. DEXTER's essay gives a broad variety of hints of how to approach and practically interview elites, which are still up-to-date. Thus the book can be labeled as a classic, despite the fact that the methodological reflections about qualitative social research, including elite interviewing or as in the German-speaking context expert interviews have become much more detailed and divers. URN: urn:nbn:de:0114-fqs080151

  19. Mind Your Grip: Even Usual Dexterous Manipulation Requires High Level Cognition

    Directory of Open Access Journals (Sweden)

    Erwan Guillery

    2017-11-01

    Full Text Available Simultaneous execution of cognitive and sensorimotor tasks is critical in daily life. Here, we examined whether dexterous manipulation, a highly habitual and seemingly automatic behavior, involves high order cognitive functions. Specifically, we explored the impact of reducing available cognitive resources on the performance of a precision grip-lift task in healthy participants of three age groups (18–30, 30–60 and 60–75 years. Participants performed a motor task in isolation (M, in combination with a low-load cognitive task (M + L, and in combination with a high-load cognitive task (M + H. The motor task consisted in grasping, lifting and holding an apparatus instrumented with force sensors to monitor motor task performance. In the cognitive task, a list of letters was shown briefly before the motor task. After completing the motor task, one letter of the list was shown, and participants reported the following letter of the list. In M + L, letters in the list followed the alphabetical order. In M + H, letters were presented in random order. Performing the high-load task thus required maintaining information in working memory. Temporal and dynamic parameters of grip and lift forces were compared across conditions. During the cognitive tasks, there was a significant alteration of movement initiation and a significant increase of grip force (GF throughout the grip-lift task. There was no interaction with “age”. Our results demonstrate that planning and the on-line control of dexterous manipulation is not an automatic behavior and, instead, that it interacts with high-level cognitive processes such as those involved in working memory.

  20. Dexterity tests data contribute to reduction in leaded glovebox gloves use

    Energy Technology Data Exchange (ETDEWEB)

    Cournoyer, Michael E [Los Alamos National Laboratory; Lawton, Cindy M [Los Alamos National Laboratory; Castro, Amanda M [Los Alamos National Laboratory

    2008-01-01

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (TA-55) involve working with various amounts of plutonium and other highly toxic, alphaemitting materials. The spread of radiological contamination on surfaces and airborne contamination and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Through an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program (GGJP). A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management owning glovebox processes through this program make decisions on which type of glovebox gloves (the weakest component of this safety significant system) would perform in these aggressive environments. As Low As Reasonably Achievable (ALARA) considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) glovebox gloves made from Hypalon(reg.) had been the workhorse of programmatic operations at TA-55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduced the amount of mixed TRU waste. This effort contributes to Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost effectiveness, and formality of glovebox operations. In the following report, the pros and cons of wearing leaded glovebox gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and pollution prevention benefits of this dramatic change in the glovebox system are presented.

  1. Dexterity Test Data Contribute To Reduction in Leaded Glovebox Glove Use

    International Nuclear Information System (INIS)

    Cournoyer, M.E.; Lawton, C.M.; Castro, A.M.; Costigan, S.A.; Schreiber, S.

    2009-01-01

    Programmatic operations at the Los Alamos National Laboratory Plutonium Facility (TA-55) involve working with various amounts of plutonium and other highly toxic, alpha-emitting materials. The spread of radiological contamination on surfaces, airborne contamination, and excursions of contaminants into the operator's breathing zone are prevented through the use of a variety of gloveboxes. Using an integrated approach, controls have been developed and implemented through an efficient Glovebox Glove Integrity Program. A key element of this program is to consider measures that lower the overall risk of glovebox operations. Line management who own glovebox processes through this program make decisions on which type of glovebox gloves (hereafter referred to as gloves), the weakest component of this safety-significant system, would perform best in these aggressive environments. As Low as Reasonably Achievable considerations must be balanced with glove durability and worker dexterity, both of which affect the final overall risk of the operation. In the past, lead-loaded (leaded) gloves made from Hypalon R were the primary glove for programmatic operations at TA-55. Replacing leaded gloves with unleaded gloves for certain operations would lower the overall risk as well as reduce the amount of mixed transuranic waste. This effort contributes to the Los Alamos National Laboratory Continuous Improvement Program by improving the efficiency, cost-effectiveness, and formality of glovebox operations. In this report, the pros and cons of wearing leaded gloves, the effect of leaded gloves versus unleaded gloves on task performance using standard dexterity tests, the justification for switching from leaded to unleaded gloves, and the pollution prevention benefits of this dramatic change in the glovebox system are presented. (authors)

  2. The value of the phase analysis for the diagnosis of COPD complicated with early cor pulmonale

    International Nuclear Information System (INIS)

    Tang Binxiang; Zhang Qingxian; Wang Shujun

    1993-01-01

    The phase analysis was examined in 14 cases of COPD complicated with early cor pulmonale, 10 cases of coronary heart disease and 19 cases of normal subjects by the radionuclide gated blood pool imaging. Right heart catheterization was also performed in COPD group. It was shown that RVW (right ventricular phase angle width) in the COPD were significantly increased than that in the coronary heart disease group and the normal group, while LVW (left ventricular phase angle width) in the coronary heart disease group were significantly increased. It was worthy to be pointed out that in 3 of 4 cases of COPD with normal pulmonary artery pressure the RVW definitely prolonged. Therefore, it was suggested that RVW may be taken as an index for diagnosis of COPD complicated with early cor pulmonale

  3. Comparison of color indexes for tomato ripening Comparação dos índices de cor para maturação do tomate

    Directory of Open Access Journals (Sweden)

    Andrés F. López Camelo

    2004-09-01

    Full Text Available Color in tomato is the most important external characteristic to assess ripeness and postharvest life, and is a major factor in the consumer's purchase decision. Degree of ripening is usually estimated by color charts. Colorimeters, on the other hand, express colors in numerical terms along the L*, a* and b* axes (from white to black, green to red and blue to yellow, respectively within the CIELAB color sphere which are usually mathematically combined to calculate the color indexes. Color indexes and their relationship to the visual color classification of tomato fruits vine ripened were compared. L*, a* and b* data (175 observations from eleven cultivars from visually classified fruits at harvest in six ripening stages according to the USDA were used to calculate hue, chroma, color index, color difference with pure red, a*/b* and (a*/b*². ANOVA analysis were performed and means compared by Duncan's MRT. Color changes throughout tomato ripening were the result of significant changes in the values of L*, a* and b*. Under the conditions of this study, hue, color index, color difference and a*/b* expressed essentially the same, and the color categories were significantly different in terms of human perception, with hue showing higher range of values. Chroma was not a good parameter to express tomato ripeness, but could be used as a good indicator of consumer acceptance when tomatoes are fully ripened. The (a*/b*² relationship had the same limitations as chroma. For vine ripened fruits, hue, color index, color difference and a*/b* could be used as objective ripening indexes. It would be interesting to find out what the best index would be if ripening took place under inadequate conditions of temperature and ilumination.A cor do tomate é a característica externa mais importante que permite determinar a maturação e estimar a vida pós-colheita, sendo por sua vez um fator importante na decisão de compra por parte do consumidor. O grau de matura

  4. Remoção de cor de efluentes têxteis com cogumelos Agaricus bispora - doi: 10.4025/actascitechnol.v32i3.6339

    Directory of Open Access Journals (Sweden)

    Renata Lopes Landeira Silva

    2010-11-01

    Full Text Available O emprego direto de cogumelos Agaricus bispora foi avaliado para a remoção de cor de uma mistura sintética de corantes reativos. Avaliou-se o efeito da granulometria das partículas (cubos de 0,5 ou 1,0 cm e cogumelos moídos, da massa de cogumelos (10, 20, 40, 60 ou 80 g em 250 mL de solução e de diferentes formas de tratamento do cogumelo sobre a remoção de cor de uma solução sintética dos corantes Reactive Yellow 37, Reactive Black 5 e Reactive Red na concentração de 13,3 mg L-1 cada corante. Os melhores resultados foram obtidos para maiores áreas superficiais de contato do cogumelo (cogumelo moído com o efluente colorido e sob aeração contínua. A adição de acetona durante o processo de moagem, seguido de congelamento, contribuiu para o aumento da remoção de cor, obtendo-se os melhores resultados: 73% após 6h, com 20 g de biocatalisador 250 mL-1 de efluente. A utilização de diferentes lotes e marcas de cogumelo levou à obtenção de diferentes atividades enzimáticas, mas percentuais similares de remoção de cor, indicando que a remoção de cor não possui relação direta com a atividade enzimática.

  5. Lesões expansivas do plexo coróide Choroid plexus mass lesions

    Directory of Open Access Journals (Sweden)

    Ernesto Lima Araújo Melo

    2003-12-01

    Full Text Available As lesões expansivas do plexo coróide constituem um grupo bastante amplo e heterogêneo de doenças e seus simuladores. Tumores, infecções, anomalias congênitas, hemorragias, cistos e fenômenos degenerativos são alguns dos exemplos de causas de lesões expansivas do plexo coróide. No presente trabalho fizemos revisão da literatura pertinente, descrevendo os achados de imagem e ilustrando-os com alguns casos do nosso serviço. Apesar de não existir na literatura descrição de sinais patognomônicos, a avaliação criteriosa e sistemática das características das lesões pode sugerir determinada etiologia.Choroid plexus mass lesions encompass a broad and heterogeneous group of diseases and their simulators. Tumors, infections, congenital anomalies, hemorrhage, cysts and degenerative diseases are some examples of mass lesions affecting the choroid plexus. In this article we review the current literature, describing the imaging findings and illustrating choroid plexus mass lesions with some cases diagnosed at our facility. Despite the inexistence of pathognomonic signs, a careful and systematic evaluation of the imaging characteristics may suggest many etiologies.

  6. Estudo anatômico das vias bilíferas em búfalos: comportamento do ductus choledocus, ductus cysticus e vesica fellea. Sistematização do ductus biliferus principalis dexter

    Directory of Open Access Journals (Sweden)

    Wilson Machado de Souza

    1994-06-01

    Full Text Available Os autores estudaram o comportamento do ductus choledocus, ductus cysticus e vesica fellea e a constituição do ductus biliferus principalis dexter, parte das vias bilíferas em 40 búfalas da raça Jaffarabadi, adultas. Os fígados tiveram suas vias biliares injetadas com látex Neoprene 650 e celobar, e o procedimento utilizado pelos autores para evidenciação dos componentes estudados foram a dissecação e radiografias. Nos 40 órgãos analisados constatou-se que o ductus choledocus na maioria (97,5% sem tributários, acolhe num caso isolado (2,5% afluente inominado do lobus quadratus. Este ductus apresenta-se formado pela confluência dos ductus biliferus principalis dexter e do sinister (75%, pela confluência das raízes dorsomedial e ventrolateral mais o ductus biliferus principalis sinister (22,5%, e pela junção do ductus hepaticus e ductus cysticus (2,5%. O ductus cysticus, componente constante do ductus biliferus principalis dexter, associa-se ao ductus biliferus lateralis lobi dextri (67,5%, endereçando-se nas outras glândulas (32,5% a troncos diversos. A vesica fellea em 87,5% das peças mostra-se livre de afluentes, enquanto nas demais dessecações (12,5% recebe duetos hepaticocísticos oriundos apenas do lobus quadratus (5%, simultaneamente do lobus dexter e do lobus quadratus (5%, e unicamente do território lateral do lobus dexter (5%. O ductus biliferus principalis dexter é formado pelo ductus lateralis lobi dextri e ductus cysticus (100% e pelo ductus medialis lobi dextri, ductus dorsalis lobi dextri e ductus processi caudati (92,5%.

  7. Estudio bibliométrico de la Revista CorSalud

    Directory of Open Access Journals (Sweden)

    Grenedys Teresa López Tápanes

    2013-10-01

    Full Text Available Objetivos: Se hizo un estudio bibliométrico de algunos indicadores en los primeros 199 artículos publicados en CorSalud, con el objetivo de conocer el estado actual y la evolución de sus contenidos. Método: Se realizó de un estudio descriptivo y transversal de forma retrospectiva, analizando los artículos publicados en la Revista CorSalud entre el primer trimestre del año 2009 y el primer trimestre del año 2013 ambos inclusive, por origen de procedencia del primer autor, tema de publicación, composición y actualización de las fuentes de referencia y número de autores firmantes. Resultados: Se analizaron un total de 199 artículos, el 73,36% de los mismos provenían de Villa Clara, la Cardiología predominó con un 50,25% de la temática, las fuentes de referencias más utilizadas fueron las revistas impresas 79,96% y la actualización de las mismas tuvo una tendencia decreciente anual del 7,78% aunque se mantuvo con una media del 47,05% y el Índice de Colaboración entre los autores alcanzó una media de 3,75%. Conclusiones: La mayoría de los artículos provenían la región central, los artículos originales, breves, de revisión y especiales fueron la generalidad. Preponderaron los temas de Cardiología, las fuentes de referencias utilizadas mayormente fueron las revistas impresas, la actualización de las mismas se mantiene en niveles comparables internacionalmente, al igual del Índice de Colaboración entre los autores que mostró además, una tendencia creciente.

  8. Variações da cor preta e negra na pintura de Eduardo Sued

    Directory of Open Access Journals (Sweden)

    Marcela Rangel

    2009-01-01

    Full Text Available Eduardo Sued transforma o pigmento preto de sua paleta física em campos cromáticos em suas pinturas. Ele costuma diferenciar a cor preta da cor negra. Diz que o preto torna-se negro à medida que a escuridão e a intensidade vão se apossando dele. Para Sued, o preto permite o passeio apenas em sua superfície, enquanto no negro há profundidade. "Há noites pretas e noites negras!" Nesta entrevista, Sued discorre sobre o que fomenta sua produção pictórica, em especial o uso que faz da tinta preta para criar seus pretos e seus negros.Eduardo Sued transforms the black pigment of his physical palette in color fields on his paintings. He usually distinguishes black from "darkblack". He says black goes to "dark black" as darkness and intensity take hold of it. For him, the black works only on its surface, while "darkblack" is deep. "There are black nights and 'darkblack' nights!" In this interview Sued talks about what promotes his pictorial production, in particular his use of black paint to create his black and darkblack fields.

  9. Influence of Shift Work on Manual Dexterity and Reaction Time in Tunisian Nurses.

    Science.gov (United States)

    Merchaoui, Irtyah; Chaari, Neila; Bouhlel, Mohamed; Bouzgarrou, Lamia; Malchaire, Jacques; Akrout, Mohamed

    2017-01-01

    Major effects of shift schedule are related to sleep alertness and performance, but also to long term health outcomes. For nurses, these negative effects have consequences not only on the individual, but also on the workplace, as decreased alertness and reduced job performance could endanger human lives. The specific aim of our study is to assess the influence of shift schedule on nurses´ cognitive ability and rapidity of execution. Our survey is a cross sectional study which had been conducted for 15 months; it involved a sample of 293 participants representative of 1118 nurses working in two Tunisian university hospitals. It included an evaluation of the rapidity of execution performance through the manual dexterity test and the reaction time test. The study was completed by an assessment of the workability Index through a 7- item survey. No association was found between the groups of work schedules and the cognitive ability of execution speed. However, we found a significant decrease in cognitive performance in the nurses exceeding 10 years of job seniority for both schedules. We concluded to an impaired cognitive performance speed in the over 10-year seniority groups in both schedules. Recommendations should be focused on implementing periodic assessment of cognitive performance based on O'Connor finger dexterity test and time reaction test and on implementing effective preventive measures in hospitals after ten years of seniority at work. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  10. Pengaruh Degasser Dan Grain Refiner Terhadap Sifat Mekanik Paduan Al-Si Produk Cor

    OpenAIRE

    Yohanes, Glenn; Djamil, Sofyan

    2008-01-01

    Paduan aluminium banyak digunakan pada industri otomotif, seperti pada pembuatan velg dan komponen-komponen mesin. Studi pengaruh degasser dan grain refiner terhadap kekuatan tarik, kekuatan luluh, elongasi dan kekerasan, pada proses peleburan dibandingkan dengan atau tanpa menggunakan degasser dan grain refiner. Benda uji didapat dengan melebur blok mesin Mitsubishi L.300, menggunakan tungku listrik dan proses cor sistem cetakan terbuka. Hasil penelitian, meliputi kekuatan tarik, luluh, elon...

  11. Pengaruh Degasser dan Grain Refiner terhadap Sifat Mekanik Paduan Al-Si Produk Cor

    OpenAIRE

    Yohanes, Glenn; Djamil, Sofyan

    2009-01-01

    Paduan aluminium banyak digunakan pada industri otomotif, seperti pada pembuatan velg dan komponen-komponen mesin. Studi pengaruh degasser dan grain refiner terhadap kekuatan tarik, kekuatan luluh, elongasi dan kekerasan, pada proses peleburan dibandingkan dengan atau tanpa menggunakan degasser dan grain refiner. Benda uji didapat dengan melebur blok mesin Mitsubishi L.300, menggunakan tungku listrik dan proses cor sistem cetakan terbuka. Hasil penelitian, meliputi kekuatan tarik, luluh, elon...

  12. A Low-Cost Open Source 3D-Printable Dexterous Anthropomorphic Robotic Hand with a Parallel Spherical Joint Wrist for Sign Languages Reproduction

    Directory of Open Access Journals (Sweden)

    Andrea Bulgarelli

    2016-06-01

    Full Text Available We present a novel open-source 3D-printable dexterous anthropomorphic robotic hand specifically designed to reproduce Sign Languages’ hand poses for deaf and deaf-blind users. We improved the InMoov hand, enhancing dexterity by adding abduction/adduction degrees of freedom of three fingers (thumb, index and middle fingers and a three-degrees-of-freedom parallel spherical joint wrist. A systematic kinematic analysis is provided. The proposed robotic hand is validated in the framework of the PARLOMA project. PARLOMA aims at developing a telecommunication system for deaf-blind people, enabling remote transmission of signs from tactile Sign Languages. Both hardware and software are provided online to promote further improvements from the community.

  13. Éloge du décor : l’église Saint-Jean-Bosco à Paris, sanctuaire national du père des orphelins

    Directory of Open Access Journals (Sweden)

    Valérie Gaudard

    2009-11-01

    Full Text Available Architecte méconnu, D. Rotter élève en 1933 le sanctuaire national de l’ordre de Saint-Jean-Bosco, soixantième chantier du cardinal Verdier. Élément d’un projet plus vaste de bâtiments destinés à l’éducation des jeunes défavorisés, l’église en béton armé, à la silhouette proche de l’église du Raincy, frappe par l’originalité, la richesse et la bonne conservation de son décor. Bessac et Gaudin signent une partie du décor dû pour l’essentiel à Mauméjean Frères. Cet unicum parisien contient l’un des derniers décors figurés d’église avant leur disparition après-guerre.

  14. ESTUDO DA ALTERAÇÃO DA COR E DEGRADAÇÃO DA CLOROFILA DURANTE ARMAZENAGEM DE ERVA-MATE TIPO CHIMARRÃO

    OpenAIRE

    Gisela Cabral Malheiros

    2007-01-01

    A Ilex paraguariensis A. St.-Hill., conhecida popularmente como erva-mate, é uma espécie nativa da região subtropical da América do Sul, a qual é matéria-prima para o produto ervamate, utilizado principalmente no preparo da bebida chimarrão. Dentre os atributos sensoriais da erva-mate tipo chimarrão, a cor constitui o primeiro critério utilizado pelo consumidor para sua aceitabilidade. A cor verde da erva-mate deve-se à presença de clorofila. Ocorrem perdas expressivas de clorofila no proc...

  15. A piano training program to improve manual dexterity and upper extremity function in chronic stroke survivors

    Directory of Open Access Journals (Sweden)

    Myriam eVilleneuve

    2014-08-01

    Full Text Available Objective: Music-supported therapy was shown to induce improvements in motor skills in stroke survivors. Whether all stroke individuals respond similarly to the intervention and whether gains can be maintained over time remain unknown. We estimated the immediate and retention effects of a piano training program on upper extremity function in persons with chronic stroke. Methods: Thirteen stroke participants engaged in a 3-week piano training comprising of supervised sessions (9 x 60min and home practice. Fine and gross manual dexterity, movement coordination and functional use of the upper extremity were assessed at baseline, pre-intervention, post-intervention and at a 3-week follow-up. Results: Significant improvements were observed for all outcomes at post-intervention and follow-up, compared to pre-intervention scores. Larger magnitudes of change in manual dexterity and functional use of the upper extremity were associated with higher initial levels of motor recovery. Conclusions: Piano training can result in sustainable improvements in upper extremity function in chronic stroke survivors. Individuals with a higher initial level of motor recovery at baseline appear to benefit the most from this intervention.

  16. Observations of the star Cor Caroli at the Apple Valley Workshop 2016

    Science.gov (United States)

    Estrada, Reed; Boyd, Sidney; Estrada, Chris; Evans, Cody; Rhoades, Hannah; Rhoades, Mark; Rhoades, Trevor

    2017-06-01

    Using a 22-inch Newtonian Alt/Az telescope and Celestron Micro Guide eyepiece, students participating in a workshop observed the binary star Cor Caroli (STF 1692) and found a position angle of 231.0 degrees as well as an average separation of 18.7" This observation compared favorably with the 2015 Washington Double Star published position. This project was part of Mark Brewer's Apple Valley Double Star Workshop. The results were analyzed using bias and circle error probability calculations.

  17. The New England Journal of Medicine, CorSalud and Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    Francisco Luis Moreno Martínez

    2012-03-01

    Full Text Available In order to commemorate the 200th anniversary of The New England Journal of Medicine, the working staff of CorSalud extends its congratulations to this prestigious medical journal. It has been demonstrated the important role this journal played by increasing scientific knowledge, specifically in the specialty of Cardiology and,of course, its editorial quality, based not only on experience but also on professionalism. All this places it as a paradigm to be followed by each and all of the journals in the medical and scientific community.

  18. Design of a Variable Stiffness Soft Dexterous Gripper

    Science.gov (United States)

    Nefti-Meziani, Samia; Davis, Steve

    2017-01-01

    Abstract This article presents the design of a variable stiffness, soft, three-fingered dexterous gripper. The gripper uses two designs of McKibben muscles. Extensor muscles that increase in length when pressurized are used to form the fingers of the gripper. Contractor muscles that decrease in length when pressurized are then used to apply forces to the fingers through tendons, which cause flexion and extension of the fingers. The two types of muscles are arranged to act antagonistically and this means that by raising the pressure in all of the pneumatic muscles, the stiffness of the system can be increased without a resulting change in finger position. The article presents the design of the gripper, some basic kinematics to describe its function, and then experimental results demonstrating the ability to adjust the bending stiffness of the gripper's fingers. It has been demonstrated that the fingers' bending stiffness can be increased by more than 150%. The article concludes by demonstrating that the fingers can be closed loop position controlled and are able to track step and sinusoidal inputs. PMID:29062630

  19. Títulos e temas de 1 Cor 6,12-20 na unidade dos capítulos 5-7 = Titles and themes of 1 cor 6.12 -20 in theunity of the chapters 5-7

    Directory of Open Access Journals (Sweden)

    Oliveira, Flávio Martinez de

    2011-01-01

    Full Text Available Apresentam-se os títulos mais encontrados em 1 Cor 6,12-20 e na unidade dos capítulos 5-7. Expõem-se as propostas de articulação da perícope na unidade para propor, a partir de tais títulos e articulação, lendo a perícope, os temas aí considerados centrais. Tais temas são uma proposta de teologia bíblica para a perícope em seu contexto. Esta inspira a existência corporal cristã, tema da tese do autor, onde introduz e motiva a exegese lá exposta. Os temas escolhidos na perícope são porneia e corpo, pecado contra o corpo, corpo de Cristo e templo do Espírito Santo. São alternativas mutuamente excludentes o contato sexual com a prostituta, que implica a inteira existência corporal, e a pertença ao corpo de Cristo, no qual somos inseridos pelo Espírito Santo, do qual somos o templo. Identidade, estilo de vida e comportamento cristãos, teologia e ética são inseparáveis. Estas relações não eram compreendidas por muitos coríntios, os quais Paulo tem em vista. O corpo é central na perícope, perpassa toda a Primeira Carta aos Coríntios e relaciona-se ao próprio Evangelho de Paulo enquanto teologia do corpo. A porneia envolve a pessoa inteira de maneira estável e é um dos problemas que colocam a comunidade em conflito, ao lado de outras controvérsias conhecidas, e com esta relacionadas, como aquelas referentes aos carismas, à idolatria e à própria autoridade de Paulo

  20. Expressão antigênica em carcinomas do plexo coróide humano: relato de dois casos

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    M. C. Almeida

    1990-09-01

    Full Text Available Neoplasias provenientes do epitélio de revestimento do plexo coróide são inco-muns, tendo sido descritos 6 padrões morfológicos. O padrão anaplásico, também denominado carcinoma do plexo coróide, é o de menor freqüência e pode dar metastases fora do SNC. A distinção histológica desses tumores, particularmente da variedade anaplásica, com outras neoplasias primárias e metastáticas no SNC pode ser difícil. O uso de técnicas imunocitoquimicas em parafina tem-se mostrado útil no esclarecimento das linhagens tumorais. Os papilomas do plexo coróide têm, no entanto, sido objeto de controvérsia, por sua complexa expressão antigênica. Usando a técnica de imunoperoxidase (sistema avidina-biotina-peroxidase pesquisaram-se, em dois casos da variedade anaplásica, os seguintes marcadores: proteína glial fibrilar ácida (GFAP com anticorpo monoclonal e policlonal; ceratinas de 40-50kDa, ceratinas de 60-70kDa (callus ceratina, enolase neuronal específica (NSE e proteína S-100, com anticorpos monoclonais. Os dois tumores mostraram positividade para NSE, proteína S-100 e ceratina de 40-50kDa; uma das duas neoplasias mostrou diferenciação glial, revelando positividade para GFAP tanto com anticorpo monoclonal quanto policlonal.

  1. Remoção da cor no tratamento combinado de lixiviado de aterro sanitário e esgoto doméstico via processo PACT®

    Directory of Open Access Journals (Sweden)

    Ángel Santiago Fernández Bou

    2018-03-01

    Full Text Available RESUMO Misturas diferentes de lixiviado de aterro sanitário e esgoto doméstico foram aplicadas em 16 reatores em batelada usando o processo PACT® (lodos ativados com adição de carvão ativado em pó - CAP. O objetivo do trabalho foi representar a remoção de cor utilizando dois ajustes matemáticos: o primeiro combinou as variáveis concentração de CAP (0 a 6 g.L-1 e mistura lixiviado/esgoto (0 a 10%, em volume; e o segundo, a concentração de CAP e a cor da mistura (276 a 1.199 uH. A metodologia de superfície de resposta (MSR foi escolhida para representar a resposta dos ajustes. Os resultados indicaram que, conforme a concentração de lixiviado aumentou até 5%, a adição de CAP resultou em um maior percentual de remoção de cor. No entanto, para a mistura com 10% de lixiviado, os reatores perderam eficácia, com exceção do reator com 6 g.L-1 de CAP, que apresentou os melhores resultados de remoção de cor.

  2. Sinéreses cromossômicas: projeto de complementaridade semiósica entre som e cor

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    Eufrásio Prates

    2008-11-01

    Full Text Available O trabalho de Basbaum transita, transdisciplinarmente, pelos campos da neurologia cognitiva, arte, fí­sica, matemática, tecnologia, misticismo e teosofia, trazidos à baila para compor a teia da sinestesia ontológica do cromo-som, complexo indissociável e simultâneo de som e cor, como busca de interconexões originárias entre som e cor a partir da esfera da primeiridade peirciana, da constituição mesma do fenômeno sinestésico. Palavras-chave Sinestesia, primeiridade. Abstract The work of Basbaum as a research on the originary interconnections between sound and color based upon the Peircian firstness sphere concern, the constitution of the synesthesic phenomenon itself , goes transdisciplinarly through the fields of cognitive neurology, arts, physics, mathematics, technology, mysticism and theosophy, all of them with regard to the weaving of the ontological; synesthesia of the chromosound, an indissociable and simultaneous complex ofsound and color. Keywords Synesthesic phenomenon, Peircian firstness.

  3. Compte rendu de la mission effectuée en Corée du 22 novembre au 6 décembre 1980

    OpenAIRE

    Perez, Rene

    1980-01-01

    Sur invitation de la Fishery Research and Development Agency, le responsable du laboratoire d'Algologie Appliquée de l'Institut Scientifique et Technique des Pêches Maritimes a effectué une mission d'études en Corée du sud du 23 novembre au 6 décembre 1980. Le but de cette mission était de s'informer sur les techniques de culture intensive d'algues à vocation alimentaire et sur les modes de conditionnement, ainsi que de définir les intentions de la Corée en ce qui concerne l'utilisation des a...

  4. CorSalud, The New England Journal of Medicine, and the International Committee of Medical Journal Editors

    Directory of Open Access Journals (Sweden)

    Francisco L. Moreno-Martínez

    2016-06-01

    Full Text Available CorSalud y The New England Journal of Medicine (NEJM coincidieron por primera vez en el título de una carta al editor en 20121, en esa ocasión fue para felicitar a tan prestigiosa revista por el bicentenario de su creación.

  5. Neuron selection based on deflection coefficient maximization for the neural decoding of dexterous finger movements.

    Science.gov (United States)

    Kim, Yong-Hee; Thakor, Nitish V; Schieber, Marc H; Kim, Hyoung-Nam

    2015-05-01

    Future generations of brain-machine interface (BMI) will require more dexterous motion control such as hand and finger movements. Since a population of neurons in the primary motor cortex (M1) area is correlated with finger movements, neural activities recorded in M1 area are used to reconstruct an intended finger movement. In a BMI system, decoding discrete finger movements from a large number of input neurons does not guarantee a higher decoding accuracy in spite of the increase in computational burden. Hence, we hypothesize that selecting neurons important for coding dexterous flexion/extension of finger movements would improve the BMI performance. In this paper, two metrics are presented to quantitatively measure the importance of each neuron based on Bayes risk minimization and deflection coefficient maximization in a statistical decision problem. Since motor cortical neurons are active with movements of several different fingers, the proposed method is more suitable for a discrete decoding of flexion-extension finger movements than the previous methods for decoding reaching movements. In particular, the proposed metrics yielded high decoding accuracies across all subjects and also in the case of including six combined two-finger movements. While our data acquisition and analysis was done off-line and post processing, our results point to the significance of highly coding neurons in improving BMI performance.

  6. The relationship between walking, manual dexterity, cognition and activity/participation in persons with multiple sclerosis.

    Science.gov (United States)

    Kierkegaard, Marie; Einarsson, Ulrika; Gottberg, Kristina; von Koch, Lena; Holmqvist, Lotta Widén

    2012-05-01

    Multiple sclerosis has a vast impact on health, but the relationship between walking, manual dexterity, cognition and activity/participation is unclear. The specific aims were to explore the discriminative ability of measures of walking, manual dexterity and cognition, and to identify cut-off values in these measures, for prediction of independence in personal and instrumental activities of daily living (ADL) and activity/participation in social and lifestyle activities. Data from 164 persons with multiple sclerosis were collected during home visits with the following measures: the 2 × 5 m walk test, the Nine-hole Peg Test, the Symbol Digit Modalities Test, the Katz Personal and Instrumental ADL Indexes, and the Frenchay Activities Index (measuring frequency in social and lifestyle activities). The 2 × 5 m walk test and the Nine-hole Peg Test had high and better discriminative and predictive ability than the Symbol Digit Modalities Test. Cut-off values were identified. The accuracy of predictions was increased above all by combining the 2 × 5 m walk test and the Nine-hole Peg Test. The proposed cut-off values in the 2 × 5 m walk test and the Nine-hole Peg Test may be used as indicators of functioning and to identify persons risking activity limitations and participation restrictions. However, further studies are needed to confirm the usefulness in clinical practice.

  7. Desigualdades sociais e tuberculose: analise segundo raca/cor, Mato Grosso do Sul

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    Paulo Cesar Basta

    2013-10-01

    Full Text Available OBJETIVO Analisar características sociodemográficas e clínico-epidemiológicas dos casos de tuberculose e fatores associados ao abandono e ao óbito na vigência do tratamento. MÉTODOS Estudo epidemiológico baseado em dados notificados de tuberculose em indígenas e não indígenas, segundo raça/cor, em Mato Grosso do Sul, entre 2001 e 2009. Realizou-se análise descritiva dos casos de acordo com as variáveis sexo, faixa etária, zona de residência, exames empregados para o diagnóstico, forma clínica, tratamento supervisionado e situação de encerramento, segundo raça/cor. Utilizou-se análise univariada e múltipla por meio de regressão logística para identificar preditores de abandono e óbito, e odds ratio como medida de associação. Foi construída série histórica de incidência, segundo raça/cor. RESULTADOS Registraram-se 6.962 casos novos de tuberculose no período, 15,6% entre indígenas. Houve predomínio em homens e adultos (20 a 44 anos em todos os grupos. A maior parte dos doentes indígenas residia na zona rural (79,8% e 13,5% dos registros nos indígenas ocorreram em 45 anos (OR = 3,0; IC95% 1,2;7,8 e com a forma mista (OR = 2,3; IC95% 1,1;5,0 apresentaram associação com óbito. Apesar de representarem 3,0% da população, os indígenas foram responsáveis por 15,6% das notificações no período. CONCLUSÕES Houve importantes desigualdades em relação ao adoecimento por tuberculose entre as categorias estudadas. As incidências nos indígenas foram consistentemente maiores, chegando a exceder em mais de seis vezes as médias nacionais. Entre pretos e pardos, piores resultados no tratamento foram observados, pois apresentaram chance de abandono duas vezes maior que os indígenas. O mau desempenho do programa também esteve fortemente associado ao abandono e ao óbito. Acredita-se que, enquanto não se reduzir a pobreza, as desigualdades nos indicadores em saúde permanecerão.

  8. L’archipel nord-coréen: transition économique et blocages territoriaux

    Directory of Open Access Journals (Sweden)

    César Ducruet

    2007-09-01

    Full Text Available L’une des caractéristiques récentes de la Corée du Nord est le manque manifeste d’intégration territoriale, en contradiction croissante avec la volonté d’ouverture économique. Dans un environnement mondialisé, le faible coût et la qualité de sa main-d’œuvre, l’abondance des ressources naturelles, et une situation stratégique entre la Corée du Sud, le Japon et leurs voisins continentaux immédiats comme la Chine et la Russie, sont autant d’atouts qui devraient permettre la mise en œuvre des réformes et la relance de l’économie. Tandis que la plupart des travaux précédents se basent sur les facteurs politiques externes pour expliquer les difficultés rencontrées (isolement dû à la disparition du bloc de l’Est, embargo imposé par les États-Unis et le Japon, cet article privilégie les facteurs spatiaux internes. L’examen successif de structures spatiales fondamentales montre que la déconnexion croissante entre les différentes provinces, conséquence d’un long déclin économique et de la dégradation des infrastructures, serait une contrainte majeure avec laquelle les projets de développement du pays sont confrontés, au-delà des aspects purement politiques.

  9. Can the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) be used to accurately report clinic total reproductive potential (TRP)?

    Science.gov (United States)

    Stern, Judy E; Hickman, Timothy N; Kinzer, Donna; Penzias, Alan S; Ball, G David; Gibbons, William E

    2012-04-01

    To assess whether total reproductive potential (TRP), the chance of a live birth from each fresh cycle (fresh cycle plus frozen transfers), could be calculated from the national Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) database and whether information not available in SART CORS resulted in significant changes to the TRP calculation. Retrospective study using SART CORS and clinic data. Three assisted reproductive technology clinics. Women undergoing ART. None. Two- and three-year TRPs for 2005 and 2006 were calculated according to patient age at cycle start by linking fresh to frozen cycles up to first live birth. Clinic records were used to adjust for (remove) frozen cycles that used more than one fresh cycle as a source of embryos and for any embryos donated to other patients or research or shipped to another facility before a live birth. TRP was higher than fresh per-cycle rates for most ages at all clinics, although accuracy was compromised when there were fewer than 20 cycles per category. Two- and 3-year TRPs differed in only 2 of 24 calculations. Adjusted TRPs differed less than three percentage points from unadjusted TRPs when volume was sufficient. Clinic TRP can be calculated from SART CORS. Data suggest that calculations of clinic TRP from the national dataset would be meaningful. Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Biomassa de Rubrivivax gelatinosus na criação de frangos de corte: desempenho animal e cor dos produtos

    Directory of Open Access Journals (Sweden)

    S.V. Avanço

    2014-12-01

    Full Text Available A bactéria Rubrivivax gelatinosus tem sido utilizada experimentalmente no tratamento despoluente de efluentes industriais de abatedouros de aves e peixes, originando uma biomassa contendo pigmentos carotenoides, substâncias que possuem a capacidade de conferir cor aos alimentos e proteger contra reações oxidativas. Este trabalho teve por objetivo verificar o efeito da biomassa de R. gelatinosus adicionada à alimentação de frangos de corte sobre o desempenho animal e a cor de carne e pele. Duzentos pintos machos Cobb 500 foram distribuídos aleatoriamente em 20 boxes para receber, do 36º ao 45º dia de criação, quatro tratamentos com diferentes quantidades de biomassa na ração (T1 [controle] - 0g/kg; T2 - 1g/kg; T3 - 2g/kg; T4 - 3g/kg, em cinco repetições. As pesagens de aves e rações para a análise de desempenho foram feitas no início da criação e ao fim de cada período de crescimento. Ao final do experimento (45 dias, 20 aves de cada tratamento foram abatidas para a determinação da cor objetiva (L - luminosidade, C - saturação, h - tom em pele e carne de peito e coxa. Os resultados obtidos foram submetidos à ANOVA, teste t para a comparação múltipla de médias e análise de regressão com nível de significância de 5%. O ganho de peso e o consumo das aves não diferiram estatisticamente entre si (P>0,05, enquanto o índice de conversão alimentar foi superior para o T1. A luminosidade da carne e da pele aumentou significativamente nos tratamentos que receberam a biomassa. O tom da cor em carne e pele aumentou em direção ao amarelo até a concentração de 2g de biomassa por kg de ração, ao passo que, na concentração de 3g/kg, o aumento foi em direção à tonalidade vermelha. Somente na carne da coxa a saturação da cor sofreu influência da presença da biomassa na dieta. Concluiu-se que, até a proporção de 3g/kg, a biomassa não prejudicou o desempenho e foi eficiente em pigmentar a pele e a carne de

  11. Observations of the Star Cor Caroli at the Apple Valley Workshop 2016 (Abstract)

    Science.gov (United States)

    Estrada, R.; Boyd, S.; Estrada, C.; Evans, C.; Rhoades, H.; Rhoades, M.; Rhoades, T.

    2017-12-01

    (Abstract only) Using a 22-inch Newtonian Alt/Az telescope and Celestron Micro Guide eyepiece, students participating in a workshop observed the binary star Cor Caroli (STF 1692; alpha CVn) and found a position angle of 231.0 degrees as well as an average separation of 18.7" This observation compared favorably with the 2015 Washington Double Star published position. This project was part of Mark Brewer's Apple Valley Double Star Workshop. The results were analyzed using bias and circle error probability calculations.

  12. Effects of action observation therapy on hand dexterity and EEG-based cortical activation patterns in patients with post-stroke hemiparesis.

    Science.gov (United States)

    Kuk, Eun-Ju; Kim, Jong-Man; Oh, Duck-Won; Hwang, Han-Jeong

    2016-10-01

    Previous reports have suggested that action observation training (AOT) is beneficial in enhancing the early learning of new motor tasks; however, EEG-based investigation has received little attention for AOT. The purpose of this study was to illustrate the effects of AOT on hand dexterity and cortical activation in patients with post-stroke hemiparesis. Twenty patients with post-stroke hemiparesis were randomly divided into either the experimental group (EG) or control group (CG), with 10 patients in each group. Prior to the execution of motor tasks (carrying wooden blocks from one box to another), subjects in the EG and CG observed a video clip displaying the execution of the same motor task and pictures showing landscapes, respectively. Outcome measures included the box and block test (BBT) to evaluate hand dexterity and EEG-based brain mapping to detect changes in cortical activation. The BBT scores (EG: 20.50 ± 6.62 at pre-test and 24.40 ± 5.42 at post-test; CG: 20.20 ± 6.12 at pre-test and 20.60 ± 7.17 at post-test) revealed significant main effects for the time and group and significant time-by-group interactions (p < 0.05). For the subjects in the EG, topographical representations obtained with the EEG-based brain mapping system were different in each session of the AOT and remarkable changes occurred from the 2nd session of AOT. Furthermore, the middle frontal gyrus was less active at post-test than at pre-test. These findings support that AOT may be beneficial in altering cortical activation patterns and hand dexterity.

  13. Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice.

    Science.gov (United States)

    Khuda-Bukhsh, Anisur Rahman; Bhattacharyya, Soumya Sundar; Paul, Saili; Dutta, Suman; Boujedaini, Naoual; Belon, Philippe

    2011-01-01

    In homeopathy, ability of ultra-high diluted drugs at or above potency 12C (diluted beyond Avogadro's limit) in ameliorating/curing various diseases is often questioned, particularly because the mechanism of action is not precisely known. We tested the hypothesis if suitable modulations of signal proteins could be one of the possible pathways of action of a highly diluted homeopathic drug, Secale cornutum 30C (diluted 10(60) times; Sec cor 30). It could successfully combat DMBA + croton oil-induced skin papilloma in mice as evidenced by histological, cytogenetical, immunofluorescence, ELISA and immunoblot findings. Critical analysis of several signal proteins like AhR, PCNA, Akt, Bcl-2, Bcl-xL, NF-κB and IL-6 and of pro-apoptotic proteins like cytochrome c, Bax, Bad, Apaf, caspase-3 and -9 revealed that Sec cor 30 suitably modulated their expression levels along with amelioration of skin papilloma. FACS data also suggested an increase of cell population at S and G2 phases and decrease in sub-G1 and G1 phages in carcinogen-treated drug-unfed mice, but these were found to be near normal in the Sec cor 30-fed mice. There was reduction in genotoxic and DNA damages in bone marrow cells of Sec Cor 30-fed mice, as revealed from cytogenetic and Comet assays. Changes in histological features of skin papilloma were noted. Immunofluorescence studies of AhR and PCNA also suggested reduced expression of these proteins in Sec cor 30-fed mice, thereby showing its anti-cancer potentials against skin papilloma. Furthermore, this study also supports the hypothesis that potentized homeopathic drugs act at gene regulatory level.

  14. Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice

    Directory of Open Access Journals (Sweden)

    Anisur Rahman Khuda-Bukhsh

    2011-01-01

    Full Text Available In homeopathy, ability of ultra-high diluted drugs at or above potency 12C (diluted beyond Avogadro's limit in ameliorating/curing various diseases is often questioned, particularly because the mechanism of action is not precisely known. We tested the hypothesis if suitable modulations of signal proteins could be one of the possible pathways of action of a highly diluted homeopathic drug, Secale cornutum 30C (diluted 1060 times; Sec cor 30. It could successfully combat DMBA + croton oil-induced skin papilloma in mice as evidenced by histological, cytogenetical, immunofluorescence, ELISA and immunoblot findings. Critical analysis of several signal proteins like AhR, PCNA, Akt, Bcl-2, Bcl-xL, NF-κB and IL-6 and of pro-apoptotic proteins like cytochrome c, Bax, Bad, Apaf, caspase-3 and -9 revealed that Sec cor 30 suitably modulated their expression levels along with amelioration of skin papilloma. FACS data also suggested an increase of cell population at S and G2 phases and decrease in sub-G1 and G1 phages in carcinogen-treated drug-unfed mice, but these were found to be near normal in the Sec cor 30-fed mice. There was reduction in genotoxic and DNA damages in bone marrow cells of Sec Cor 30-fed mice, as revealed from cytogenetic and Comet assays. Changes in histological features of skin papilloma were noted. Immunofluorescence studies of AhR and PCNA also suggested reduced expression of these proteins in Sec cor 30-fed mice, thereby showing its anti-cancer potentials against skin papilloma. Furthermore, this study also supports the hypothesis that potentized homeopathic drugs act at gene regulatory level.

  15. Treatment of singultus by sexual stimulation: Who was George T Dexter, MD (c1812-?)?

    Science.gov (United States)

    Petroianu, Georg A

    2016-05-01

    This short report attempts to shed light on the interesting but controversial personality of George T Dexter (ca1812 -?), the physician who first described manipulation of the female genitalia in a hysterical impressionable girl as being associated with the termination of singultus. Although his interaction with the young female patient would not meet today's ethical standards, his medical observation was valid and contributes to our understanding of the pathophysiology of singultus. He was well ahead of his colleagues who presented hiccup therapy case reports with similar or related pathophysiology mechanisms some 150 years later. © IMechE 2014.

  16. Validation of birth outcomes from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS): population-based analysis from the Massachusetts Outcome Study of Assisted Reproductive Technology (MOSART).

    Science.gov (United States)

    Stern, Judy E; Gopal, Daksha; Liberman, Rebecca F; Anderka, Marlene; Kotelchuck, Milton; Luke, Barbara

    2016-09-01

    To assess the validity of outcome data reported to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) compared with data from vital records and the birth defects registry in Massachusetts. Longitudinal cohort. Not applicable. A total of 342,035 live births and fetal deaths from Massachusetts mothers giving birth in the state from July 1, 2004, to December 31, 2008; 9,092 births and fetal deaths were from mothers who had conceived with the use of assisted reproductive technology (ART) and whose cycle data had been reported to the SART CORS. Not applicable. Percentage agreement between maternal race and ethnicity, delivery outcome (live birth or fetal death), plurality (singleton, twin, or triplet+), delivery date, and singleton birth weight reported in the SART CORS versus vital records; sensitivity and specificity for birth defects among singletons as reported in the SART CORS versus the Massachusetts Birth Defects Monitoring Program (BDMP). There was >95% agreement between the SART CORS and vital records for fields of maternal race/ethnicity, live birth/fetal death, and plurality; birth outcome date was within 1 day with 94.9% agreement and birth weight was within 100 g with 89.6% agreement. In contrast, sensitivity for report of any birth defect was 38.6%, with a range of 18.4%-50.0%, for specific birth defect categories. Although most SART CORS outcome fields are accurately reported, birth defect variables showed poor sensitivity compared with the gold standard data from the BDMP. We suggest that reporting of birth defects be discontinued. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  17. Acute pulmonary embolism: prediction of cor pulmonale and short-term patient survival from assessment of cardiac dimensions in routine multidetector-row CT

    International Nuclear Information System (INIS)

    Engeike, C.; Rummeny, E.; Marten, K.

    2006-01-01

    Purpose: evaluation of the prognostic value of morphological cardiac parameters in patients with suspected and incidental acute pulmonary embolism (PE) using multidetector-row chest CT (MSCT). Materials and methods: 2335 consecutive MSCT scans were evaluated for the presence of PE. The arterial enhancement and analysability of pulmonary arteries and the heart were assessed as parameters of the scan quality. The diastolic right and left ventricular short axes (RV D , LV D ) and the interventricular septal deviation (ISD) were measured in all PE-positive patients and the echocardiography reports were reviewed. The clinical data assessment included cardio-respiratory and other co-morbidities, systemic anticoagulant therapy (ACT), and the 30-day outcome. Predictors of acute cor pulmonale and the short-term outcome were calculated by univariate and multivariate logistic regressions including odds ratios (OR) and ROC analyses using positive (PPV) and negative predictive values (NPV). Results: 90 patients with acute PE were included (36 with clinically suspected PE, 54 with incidental PE). 26 patients had cardio-respiratory co-morbidities. Four patients underwent systemic thrombolysis, 43 underwent anticoagulation in therapeutic doses, 19 underwent anticoagulation in prophylactic doses, and 24 patients did not undergo ACT. 15 of 41 patients had echocardiographic evidence of acute cor pulmonale. 8 patients died within 30 days. The RV D was the best independent predictor of acute cor pulmonale (p = 0,002, OR = 9.16, PPV = 0.68, NPV=1 at 4.49 cm cut off) and short-term outcome (p= 0,0005, OR = 2.82, PPV = 0.23, NPV = 0.98 at 4.75 cm cut off). The RV D /LV D ratio had a PPV of 0.85 for cor pulmonale. (orig.)

  18. Predicting hand function in older adults: evaluations of grip strength, arm curl strength, and manual dexterity.

    Science.gov (United States)

    Liu, Chiung-Ju; Marie, Deana; Fredrick, Aaron; Bertram, Jessica; Utley, Kristen; Fess, Elaine Ewing

    2017-08-01

    Hand function is critical for independence in activities of daily living for older adults. The purpose of this study was to examine how grip strength, arm curl strength, and manual dexterous coordination contributed to time-based versus self-report assessment of hand function in community-dwelling older adults. Adults aged ≥60 years without low vision or neurological disorders were recruited. Purdue Pegboard Test, Jamar hand dynamometer, 30-second arm curl test, Jebsen-Taylor Hand Function Test, and the Late-Life Function and Disability Instrument were administered to assess manual dexterous coordination, grip strength, arm curl strength, time-based hand function, and self-report of hand function, respectively. Eighty-four adults (mean age = 72 years) completed the study. Hierarchical multiple regressions show that older adults with better arm curl strength (β = -.25, p function test. In comparison, older adults with better grip strength (β = .40, p function. The relationship between grip strength and hand function may be test-specific. Grip strength becomes a significant factor when the test requires grip strength to successfully complete the test tasks. Arm curl strength independently contributed to hand function in both time-based and self-report assessments, indicating that strength of extrinsic muscles of the hand are essential for hand function.

  19. Articulações entre gênero e raça/cor em situações de violência de gênero

    Directory of Open Access Journals (Sweden)

    Raquel da Silva Silveira

    2014-08-01

    Full Text Available Este artigo discute teoricamente as articulações entre gênero e raça/cor na temática da violência de gênero nas relações de intimidade. A fundamentação teórica é composta pelos estudos de Michel Foucault sobre as relações de poder, pelos estudos contemporâneos de gênero (Joan Scott, Heleith Saffioti, Karin Smigay e pelos estudos de raça/cor (Florestan Fernandes, Lilia Schwarcz. O trabalho de campo, envolvendo entrevistas e análise de andamento de processos judiciais, foi desenvolvido no Juizado de Violência Doméstica e Familiar contra a Mulher e na Delegacia da Mulher, em Porto Alegre, no período de maio de 2010 a outubro de 2011. Destaca-se como necessária a problematização sobre as formas como as questões de raça/cor se entrecruzam nos discursos sobre violência de gênero nas relações de intimidade, uma vez que a maneira como as vulnerabilidades são vividas pelas mulheres variam fortemente de acordo com suas experiências singulares de vida e com os marcadores sociais.

  20. Deficiência de tiamina como causa de cor pulmonale reversível

    Directory of Open Access Journals (Sweden)

    Liana S. Coelho

    2008-07-01

    Full Text Available A deficiência de tiamina pode apresentar quatro formas clássicas de apresentação clínica: polineuropatia periférica, anorexia e fraqueza muscular (beribéri seco; insuficiência cardíaca de alto débito com sinais congestivos (beribéri úmido; beribéri associado ao choque (Shoshin beribéri e encefalopatia de Wernicke. Neste relato, descrevemos quadro sugestivo de hipertensão pulmonar grave e cor pulmonale, com estase jugular, hepatite congestiva e edema generalizado, que apresentou reversão completa após administração de tiamina.

  1. Capturing and Processing Soil GHG Fluxes Using the LI-COR LI-8100A

    Science.gov (United States)

    Xu, Liukang; McDermitt, Dayle; Hupp, Jason; Johnson, Mark; Madsen, Rod

    2015-04-01

    The LI-COR LI-8100A Automated Soil CO2 Flux System is designed to measure soil CO2 efflux using automated chambers and a non-steady state measurement protocol. While CO2 is an important gas in many contexts, it is not the only gas of interest for many research applications. With some simple plumbing modifications, many third party analyzers capable of measuring other trace gases, e.g. N2O, CH4, or 13CO2 etc., can be interfaced with the LI-8100A System, and LI-COR's data processing software (SoilFluxPro™) can be used to compute fluxes for these additional gases. In this paper we describe considerations for selecting an appropriate third party analyzer to interface with the system, how to integrate data into the system, and the procedure used to compute fluxes of additional gases in SoilFluxPro™. A case study is presented to demonstrate methane flux measurements using an Ultra-Portable Greenhouse Gas Analyzer (Ultra-Portable GGA, model 915-0011), manufactured by Los Gatos Research and integrated into the LI-8100A System. Laboratory and field test results show that the soil CO2 efflux based on the time series of CO2 data measured either with the LI-8100A System or with the Ultra-Portable GGA are essentially the same. This suggests that soil GHG fluxes measured with both systems are reliable.

  2. A vigilante serial killer as ethics educator? An exploration of Dexter as a tool for moral education in the professional domain

    NARCIS (Netherlands)

    Ommen, M.E. van; Daalmans, S.; Weijers, G.W.M.; Eden, A.; Leeuw, R.N.H. de; Buijzen, M.A.

    2017-01-01

    This study aims to inform the discussion over the proposed merit of morally ambiguous dramas as a tool in moral education in the professional domain, by providing insight into student groups' moral evaluations of Dexter. In-depth interviews (N = 61) were conducted among a diverse sample of law and

  3. Plexo coróide hipertrofiado (demonstrado angiogràficamente e hidrocefalia

    Directory of Open Access Journals (Sweden)

    Gilberto Machado de Almeida

    1964-12-01

    Full Text Available É discutido e mesmo pôsto em dúvida por alguns autores, o papel desempenhado pelo aumento de produção do líquido cefalorraqueano (LCR, na patogênese da hidrocefalia. No caso apresentado foram encontrados os seguintes elementos que indicam ser o aumento de produção do LCR a causa da hipertensão intracraniana: 1 hipertrofia dos plexos coróides sugerida pelas angiografias e confirmada pelo ato cirúrgico e necropsia; 2 ausência de bloqueio ao trânsito do LCR; 3 grande aumento do espaço subaracnói-deo, mais evidente ao nível das cisternas, inclusive inter-hemisférica e silviana.

  4. El Corsé nocturno ISJ 3D en el tratamiento de las escoliosis

    OpenAIRE

    González Vicente, Luis

    2017-01-01

    La escoliosis más estudiada es la escoliosis idiopática del adolescente (EIA). Su etiología sigue siendo desconocida. La escoliosis es una deformidad vertebral de diversos orígenes. A pesar de que su aspecto clínico que puede ser parecido, las escoliosis de un u otro grupo etiológico pueden tener pronósticos muy dispares, por la diferente progresividad y gravedad de sus curvas. El índice de efectividad del corsé ISJ es alto en todas las curvas. El sexo no influye en los resultados. ...

  5. Surrogate: A Body-Dexterous Mobile Manipulation Robot with a Tracked Base

    Science.gov (United States)

    Kennedy, Brett A. (Inventor); Hebert, Paul (Inventor); Ma, Jeremy C. (Inventor); Borders, James W. (Inventor); Bergh, Charles F. (Inventor); Hudson, Nicolas H. (Inventor)

    2018-01-01

    Robotics platforms in accordance with various embodiments of the invention can be utilized to implement highly dexterous robots capable of whole body motion. Robotics platforms in accordance with one embodiment of the invention include: a memory containing a whole body motion application; a spine, where the spine has seven degrees of freedom and comprises a spine actuator and three spine elbow joints that each include two spine joint actuators; at least one limb, where the at least one limb comprises a limb actuator and three limb elbow joints that each include two limb joint actuators; a tracked base; a connecting structure that connects the at least one limb to the spine; a second connecting structure that connects the spine to the tracked base; wherein the processor is configured by the whole body motion application to move the at least one limb and the spine to perform whole body motion.

  6. Physical Demand but Not Dexterity Is Associated with Motor Flexibility during Rapid Reaching in Healthy Young Adults.

    Directory of Open Access Journals (Sweden)

    Christian Greve

    Full Text Available Healthy humans are able to place light and heavy objects in small and large target locations with remarkable accuracy. Here we examine how dexterity demand and physical demand affect flexibility in joint coordination and end-effector kinematics when healthy young adults perform an upper extremity reaching task. We manipulated dexterity demand by changing target size and physical demand by increasing external resistance to reaching. Uncontrolled manifold analysis was used to decompose variability in joint coordination patterns into variability stabilizing the end-effector and variability de-stabilizing the end-effector during reaching. Our results demonstrate a proportional increase in stabilizing and de-stabilizing variability without a change in the ratio of the two variability components as physical demands increase. We interpret this finding in the context of previous studies showing that sensorimotor noise increases with increasing physical demands. We propose that the larger de-stabilizing variability as a function of physical demand originated from larger sensorimotor noise in the neuromuscular system. The larger stabilizing variability with larger physical demands is a strategy employed by the neuromuscular system to counter the de-stabilizing variability so that performance stability is maintained. Our findings have practical implications for improving the effectiveness of movement therapy in a wide range of patient groups, maintaining upper extremity function in old adults, and for maximizing athletic performance.

  7. Tumores do plexo coróideo

    Directory of Open Access Journals (Sweden)

    PIANETTI GERALDO

    1998-01-01

    Full Text Available É feita análise estatística, semiológica, terapêutica e da evolução de 15 crianças portadoras de tumor do plexo coróideo, tratadas cirurgicamente no Serviço de Neuropediatria dos Hospitais das Clínicas (UFMG e São Francisco de Assis, num período de 15 anos (1981 a 1996. A idade variou de quatro meses a 16 anos, com média de três anos e seis meses, dez tinham menos de dois anos; nove eram do sexo feminino; 14 tinham sinais de hipertensão intracraniana; em todas elas a presença do tumor foi confirmada pelo estudo com tomografia computadorizada; em oito crianças o tumor estava localizado em um ventrículo lateral. Das 15 crianças, 11 necessitaram de derivação ventrículo-peritoneal; a exerese radical do tumor foi possível em 13 das 14 crianças operadas. O diagnóstico anátomo-patológico foi papiloma em 12 crianças e carcinoma nas outras duas. Duas crianças faleceram, uma no sétimo dia de pós-operatório e a outra 12 meses após, com metástases disseminadas pelo sistema nervoso central. É feita revisão da literatura pertinente e dados são comparados.

  8. A Vigilante Serial Killer as Ethics Educator? An Exploration of "Dexter" as a Tool for Moral Education in the Professional Domain

    Science.gov (United States)

    van Ommen, Merel; Daalmans, Serena; Weijers, Addy; Eden, Allison; de Leeuw, Rebecca N. H.; Buijzen, Moniek

    2017-01-01

    This study aims to inform the discussion over the proposed merit of morally ambiguous dramas as a tool in moral education in the professional domain, by providing insight into student groups' moral evaluations of "Dexter." In-depth interviews (N = 61) were conducted among a diverse sample of law and (developmental) psychology students.…

  9. Virtual airway simulation to improve dexterity among novices performing fibreoptic intubation.

    Science.gov (United States)

    De Oliveira, G S; Glassenberg, R; Chang, R; Fitzgerald, P; McCarthy, R J

    2013-10-01

    We developed a virtual reality software application (iLarynx) using built-in accelerometer properties of the iPhone(®) or iPad(®) (Apple Inc., Cupertino, CA, USA) that mimics hand movements for the performance of fibreoptic skills. Twenty novice medical students were randomly assigned to virtual airway training with the iLarynx software or no additional training. Eight out of the 10 subjects in the standard training group had at least one failed (> 120 s) attempt compared with two out of the 10 participants in the iLarynx group (p = 0.01). There were a total of 24 failed attempts in the standard training group and four in the iLarynx group (p < 0.005). Cusum analysis demonstrated continued group improvement in the iLarynx, but not in the standard training group. Virtual airway simulation using freely available software on a smartphone/tablet device improves dexterity among novices performing upper airway endoscopy. © 2013 The Association of Anaesthetists of Great Britain and Ireland.

  10. Disclosure Control using Partially Synthetic Data for Large-Scale Health Surveys, with Applications to CanCORS

    OpenAIRE

    Loong, Bronwyn; Zaslavsky, Alan M.; He, Yulei; Harrington, David P.

    2013-01-01

    Statistical agencies have begun to partially synthesize public-use data for major surveys to protect the confidentiality of respondents’ identities and sensitive attributes, by replacing high disclosure risk and sensitive variables with multiple imputations. To date, there are few applications of synthetic data techniques to large-scale healthcare survey data. Here, we describe partial synthesis of survey data collected by CanCORS, a comprehensive observational study of the experiences, treat...

  11. Cinética da degradação de carotenoides e da alteração de cor do azeite de pequi submetido ao aquecimento em temperatura de fritura

    Directory of Open Access Journals (Sweden)

    Mara Lina Rodrigues

    2013-08-01

    Full Text Available O azeite de pequi possui coloração vermelho-alaranjada devido à presença de carotenoides. Possíveis alterações químicas nesses compostos durante o processamento podem influenciar em modificações físicas do produto que ocorrem quando este é submetido ao aquecimento. Este estudo teve como objetivo utilizar parâmetros cinéticos para avaliar a degradação de carotenoides e a alteração de cor do azeite de pequi submetido ao aquecimento em temperatura de fritura. Para avaliar o efeito do aquecimento, o azeite de pequi foi tratado termicamente a 180°C em intervalo crescente de 10 minutos até uma hora de aquecimento. Realizaram-se as análises de carotenoides totais e cor e com esses resultados determinaram-se os parâmetros cinéticos. Ao longo do aquecimento, o teor de carotenoides foi praticamente todo degradado e consequentemente a cor foi bastante alterada. A cinética de degradação dos carotenoides foi de primeira ordem e da alteração de cor foi de ordem zero. Essas cinéticas refletiram as observações visuais das amostras do azeite de pequi obtidas depois de cada tratamento.

  12. Disclosure control using partially synthetic data for large-scale health surveys, with applications to CanCORS.

    Science.gov (United States)

    Loong, Bronwyn; Zaslavsky, Alan M; He, Yulei; Harrington, David P

    2013-10-30

    Statistical agencies have begun to partially synthesize public-use data for major surveys to protect the confidentiality of respondents' identities and sensitive attributes by replacing high disclosure risk and sensitive variables with multiple imputations. To date, there are few applications of synthetic data techniques to large-scale healthcare survey data. Here, we describe partial synthesis of survey data collected by the Cancer Care Outcomes Research and Surveillance (CanCORS) project, a comprehensive observational study of the experiences, treatments, and outcomes of patients with lung or colorectal cancer in the USA. We review inferential methods for partially synthetic data and discuss selection of high disclosure risk variables for synthesis, specification of imputation models, and identification disclosure risk assessment. We evaluate data utility by replicating published analyses and comparing results using original and synthetic data and discuss practical issues in preserving inferential conclusions. We found that important subgroup relationships must be included in the synthetic data imputation model, to preserve the data utility of the observed data for a given analysis procedure. We conclude that synthetic CanCORS data are suited best for preliminary data analyses purposes. These methods address the requirement to share data in clinical research without compromising confidentiality. Copyright © 2013 John Wiley & Sons, Ltd.

  13. Plasma levels of leptin, omentin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26 and adiponectin before and after oral glucose uptake in slim adults

    Directory of Open Access Journals (Sweden)

    Schäffler Andreas

    2007-02-01

    Full Text Available Abstract Background Adipose tissue secreted proteins are collectively named adipocytokines and include leptin, adiponectin, resistin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26 and omentin. Several of these adipocytokines influence insulin sensitivity and glucose metabolism and therefore systemic levels may be affected by oral glucose uptake. Whereas contradictory results have been published for leptin and adiponectin, resistin has not been extensively investigated and no reports on omentin and CORS-26 do exist. Methods Therefore the plasma levels of these proteins before and 120 min after an oral glucose load were analyzed in 20 highly-insulin sensitive, young adults by ELISA or immunoblot. Results Circulating leptin was reduced 2 h after glucose uptake whereas adiponectin and resistin levels are not changed. Distribution of adiponectin and CORS-26 isoforms were similar before and after glucose ingestion. Omentin is highly abundant in plasma and immunoblot analysis revealed no alterations when plasma levels before and 2 h after glucose intake were compared. Conclusion Taken together our data indicate that only leptin is reduced by glucose uptake in insulin-sensitive probands whereas adiponectin and resistin are not altered. CORS-26 was demonstrated for the first time to circulate as high molecular weight form in plasma and like omentin was not influenced by oral glucose load. Omentin was shown to enhance insulin-stimulated glucose uptake but systemic levels are not correlated to postprandial blood glucose.

  14. Hemispheric specialization in affective responses, cerebral dominance for language, and handedness: Lateralization of emotion, language, and dexterity.

    Science.gov (United States)

    Costanzo, Elsa Yolanda; Villarreal, Mirta; Drucaroff, Lucas Javier; Ortiz-Villafañe, Manuel; Castro, Mariana Nair; Goldschmidt, Micaela; Wainsztein, Agustina Edith; Ladrón-de-Guevara, María Soledad; Romero, Carlos; Brusco, Luis Ignacio; Camprodon, Joan A; Nemeroff, Charles; Guinjoan, Salvador Martín

    2015-07-15

    Hemispheric specialization in affective responses has received little attention in the literature. This is a fundamental variable to understand circuit dynamics of networks subserving emotion. In this study we put to test a modified "valence" hypothesis of emotion processing, considering that sadness and happiness are processed by each hemisphere in relation to dominance for language and handedness. Mood induction and language activation during functional magnetic resonance imaging (fMRI) were used in 20 right-handed and 20 nonright-handed subjects, focusing on interconnected regions known to play critical roles in affective responses: subgenual cingulate cortex, amygdala, and anterior insular cortex. We observed a consistent relationship between lateralization of affective processing, motor dexterity, and language in individuals with clear right-handedness. Sadness induces a greater activation of right-hemisphere cortical structures in right-handed, left-dominant individuals, which is not evident in nonright-handed subjects who show no consistent hemispheric dominance for language. In anterior insula, right-handed individuals displayed reciprocal activation of either hemisphere depending upon mood valence, whereas amygdala activation was predominantly left-sided regardless of mood valence. Nonright-handed individuals exhibited less consistent brain lateralization of affective processing regardless of language and motor dexterity lateralization. In contrast with traditional views on emotion processing lateralization, hemispheric specialization in affective responses is not a unitary process but is specific to the brain structure being activated. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Ibi et cor tuum: The Twin Perils of Studium and Otium in English Renaissance Intellectual Culture

    OpenAIRE

    Obi, Gertrude

    2016-01-01

    My dissertation, “Ibi et cor tuum: The Twin Perils of Studium and Otium in English Renaissance Intellectual Culture,” investigates the ways in which the temptations posed by intellectual labor were conceptualized and navigated by English Renaissance humanists. The competition pitting the vita activa against the vita contemplativa, which every age—including ours—must resolve anew, generated a spate of writings engaging with the mixed legacy of classical and medieval Christian attitudes towards...

  16. the strategy of finger use in children's addition Relationship with short-term memory, finger dexterity, and addition skills

    OpenAIRE

    Asakawa, Atsushi; Sugimura, Shinichiro

    2009-01-01

    Previous research has shown that the children's use of the fingers in additon changes with age. In this study, a part of data on the strategy of finger use by Asakawa and Sugimura (2009) was reanalyzed to clarify the relationship between, short-term memory, finger dexterity and addition skills. A two-way ANOVA showed a significant interaction between memory span and finger use. Examination of simple main effect indicated that significant effect of memory span at the group of the children who ...

  17. Cor, capacidade de retenção de água e maciez da carne de cordeiro maturada e injetada com cloreto de cálcio

    OpenAIRE

    Zeola,N.M.B.L.; Souza,P.A.; Souza,H.B.A.; Silva Sobrinho,A.G.; Barbosa,J.C.

    2007-01-01

    Os músculos Biceps femoris, Longissimus e Triceps brachii submetidos aos efeitos do tempo de maturação e da injeção com cloreto de cálcio de cordeiros Morada Nova foram estudados quanto às características de cor, capacidade de retenção de água e maciez. Os cordeiros foram abatidos ao atingirem 25kg de peso vivo. Os músculos apresentaram diferenças na cor (luminosidade-L*, teor de vermelho-a* e teor de amarelo-b*) 24 horas após o abate. A maturação tendeu a escurecer a carne. O cloreto de cálc...

  18. Development of system technology for radiation cancer therapy with the dexterous auto lesions tracking

    International Nuclear Information System (INIS)

    Kim, Seungho; Jeong, Kyungmin; Jung, Seungho; Lee, Namho

    2013-01-01

    The project objectives are to establish the fundamental core technologies for precise auto lesions tracking radiation cancer therapy and developing related system technology as well. Radiation cancer therapy apparatus should be domestically produced to reduce medical expenses, hence advanced technologies are suggested and developed to make cost down medical expenses and save expenditure for importing 10 million dollars/set from overseas. To achieve these targets, we have carried out reviewing of domestic and foreign technology trend. Based on review of state-of-the-art technology, radiation sensory system is studied. 3m high precise image processing technique and intelligent therapy planning software are developed. Also precedent study on the redundant robot for dexterous motion control system has been performed for developing of radiation cancel therapy robot system

  19. Trouver la bonne distance : étrangère, marginale, ethnologue et parente en Corée du Sud

    Directory of Open Access Journals (Sweden)

    Élise Prébin

    2009-03-01

    Full Text Available Trouver la bonne distance : étrangère, marginale, ethnologue et parente en Corée du Sud. Cet article a pour sujet ma relation à la société sud-coréenne, non seulement en tant qu’anthropologue mais aussi en tant que personne adoptée d’origine coréenne. Il relate la manière dont plusieurs sortes de relations ont dû être gérées pendant le terrain. Il a fallu d’un côté me rapprocher de mes informateurs pour pouvoir mener un terrain classique dans une société inconnue, comprendre une culture autre et traiter un sujet relevant des sciences sociales : le retour des adoptés étrangers dans leur pays d’origine. De l’autre, il a fallu établir une bonne distance avec ma famille biologique coréenne en m’en éloignant momentanément. Ma relation avec elle était en effet instable du fait qu’elle reposait sur une contradiction : mon statut d’étrangère en dépit de l’intimité que supposaient les liens du sang. Pourtant, cette relation continue entre ma famille biologique et moi-même a éclairé certaines ambiguïtés relatives au statut des adoptés dans la société sud-coréenne que le temps limité du terrain n’avait pas permis de saisir. Cet article ébauche donc une réflexion épistémologique sur la pertinence d’éléments biographiques dans le traitement anthropologique de certains sujets. Je montre en l’occurrence comment le don en mariage d’une fille biologique adoptée conjure de manière satisfaisante un don en adoption toujours problématique.Finding the right distance: stranger, marginal, ethnologist and relative in south Korea. The topic of this article is my relation to the South Korean society, not only as a social anthropologist but also as a Korean adoptee. I relate the way I had to manage contrasted relations while conducting fieldwork. On one hand, I endeavoured to get closer to my informants in order to conduct classic fieldwork in an unknown society, to understand a different culture

  20. Advanced dexterous manipulation for IED defeat : report on the feasibility of using the ShadowHand for remote operations.

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert J.

    2011-01-01

    Improvised Explosive Device (IED) defeat (IEDD) operations can involve intricate operations that exceed the current capabilities of the grippers on board current bombsquad robots. The Shadow Dexterous Hand from the Shadow Robot Company or 'ShadowHand' for short (www.shadowrobot.com) is the first commercially available robot hand that realistically replicates the motion, degrees-of-freedom and dimensions of a human hand (Figure 1). In this study we evaluate the potential for the ShadowHand to perform potential IED defeat tasks on a mobile platform.

  1. Dexterous hand gestures recognition based on low-density sEMG signals for upper-limb forearm amputees

    Directory of Open Access Journals (Sweden)

    John Jairo Villarejo Mayor

    2017-08-01

    Full Text Available Abstract Introduction Intuitive prosthesis control is one of the most important challenges in order to reduce the user effort in learning how to use an artificial hand. This work presents the development of a novel method for pattern recognition of sEMG signals able to discriminate, in a very accurate way, dexterous hand and fingers movements using a reduced number of electrodes, which implies more confidence and usability for amputees. Methods The system was evaluated for ten forearm amputees and the results were compared with the performance of able-bodied subjects. Multiple sEMG features based on fractal analysis (detrended fluctuation analysis and Higuchi’s fractal dimension combined with traditional magnitude-based features were analyzed. Genetic algorithms and sequential forward selection were used to select the best set of features. Support vector machine (SVM, K-nearest neighbors (KNN and linear discriminant analysis (LDA were analyzed to classify individual finger flexion, hand gestures and different grasps using four electrodes, performing contractions in a natural way to accomplish these tasks. Statistical significance was computed for all the methods using different set of features, for both groups of subjects (able-bodied and amputees. Results The results showed average accuracy up to 99.2% for able-bodied subjects and 98.94% for amputees using SVM, followed very closely by KNN. However, KNN also produces a good performance, as it has a lower computational complexity, which implies an advantage for real-time applications. Conclusion The results show that the method proposed is promising for accurately controlling dexterous prosthetic hands, providing more functionality and better acceptance for amputees.

  2. Raciocínio pictórico: campos de cor no espaço

    OpenAIRE

    Tassinari, Roberta

    2011-01-01

    O objeto de pesquisa desta dissertação compreende a elaboração, construção e análise teórica de campos de cor no espaço tridimensional, desenvolvidos através de um raciocínio pictórico. O ponto de partida para a criação dos trabalhos ocorre por meio de apropriação de objetos do uso comum do cotidiano. Para abordar este aspecto, será utilizado o conceito de transfiguração, de Arthur Danto, na medida em que esses materiais ordinários têm a sua função subtraída ao operarem como matéria-prima na ...

  3. Producing Coordinate Time Series for Iraq's CORS Site for Detection Geophysical Phenomena

    Directory of Open Access Journals (Sweden)

    Oday Yaseen Mohamed Zeki Alhamadani

    2018-01-01

    Full Text Available Global Navigation Satellite Systems (GNSS have become an integral part of wide range of applications. One of these applications of GNSS is implementation of the cellular phone to locate the position of users and this technology has been employed in social media applications. Moreover, GNSS have been effectively employed in transportation, GIS, mobile satellite communications, and etc. On the other hand, the geomatics sciences use the GNSS for many practical and scientific applications such as surveying and mapping and monitoring, etc. In this study, the GNSS raw data of ISER CORS, which is located in the North of Iraq, are processed and analyzed to build up coordinate time series for the purpose of detection the Arabian tectonic plate motion over seven years and a half. Such coordinates time series have been produced very efficiently using GNSS Precise Point Positioning (PPP. The daily PPP results were processed, analyzed, and presented as coordinate time series using GPS Interactive Time Series Analysis. Furthermore, MATLAB (V.2013a is used in this study to computerize GITSA with Graphic User Interface (GUI. The objective of this study was to investigate both of the homogeneity and consistency of the Iraq CORSs GNSS raw data for detection any geophysical changes over long period of time. Additionally, this study aims to employ free online PPP services, such as CSRS_PPP software, for processing GNSS raw data for generation GNSS coordinate time series. The coordinate time series of ISER station showed a +20.9 mm per year, +27.2 mm per year, and -11.3 mm per year in the East, North, and up-down components, respectively. These findings showed a remarkable similarity with those obtained by long-term monitoring of Earth's crust deformation and movement based on global studies and this highlights the importance of using GNSS for monitoring the movement of tectonic plate motion based on CORS and online GNSS data processing services over long period of

  4. Quantitative evaluation of right ventricular overload in cor pulmonale using 201Tl myocardial SPECT

    International Nuclear Information System (INIS)

    Kato, Hiroshi; Misawa, Toshihiro; Kutsumi, Yasunori

    1991-01-01

    To determine quantitatively the discriminant and characteristics of cor pulmonale, 201 Tl myocardial perfusion SPECT was performed in 16 patients with chronic obstructive pulmonary disease (COPD) and 7 with restrictive pulmonary disease (RPD). One section of the short-axis SPECT image in which the right ventricle was most clearly visualized was selected. Tl-score was defined as the ratio of the sum of counts in the region of interest (ROI) at the anterior, mid, and posterior regions of the right ventricular free wall to the sum of counts in ROI at the posterior, lateral, and anterior walls of the left ventricle, and the anterior and posterior regions of the interventricular septum. In the group of COPD patients, Tl-score was positively correlated with mean pulmonary arterial pressure (mPAP), total pulmonary vascular resistance (TPR), and arterial carbon dioxide tension (PaCO 2 ), while it was inversely correlated with arterial oxygen tension (PaO 2 ). However, there was no significant correlation between Tl-score and mPAP, TPR, PaCO 2 , and PaO 2 in the group of RPD patients. In assessing pulmonary hypertension as defined by mPAP over 20 mmHg, a Tl-score greater than 0.25 was useful with a sensitivity of 69% and a specificity of 90%. The occurrence of cor pulmonale is a major factor in determining the prognosis of COPD patients. It was concluded that 201 Tl myocardial SPECT is useful for evaluating right ventricular overload quantitatively, as well as for assessing core pulmonale, especially in COPD patients, since the ratio of Tl counts in the right and left ventricles was significantly correlated with right cardiopulmonary hemodynamic parameters. (N.K.)

  5. Method and System for Controlling a Dexterous Robot Execution Sequence Using State Classification

    Science.gov (United States)

    Sanders, Adam M. (Inventor); Platt, Robert J., Jr. (Inventor); Quillin, Nathaniel (Inventor); Permenter, Frank Noble (Inventor); Pfeiffer, Joseph (Inventor)

    2014-01-01

    A robotic system includes a dexterous robot and a controller. The robot includes a plurality of robotic joints, actuators for moving the joints, and sensors for measuring a characteristic of the joints, and for transmitting the characteristics as sensor signals. The controller receives the sensor signals, and is configured for executing instructions from memory, classifying the sensor signals into distinct classes via the state classification module, monitoring a system state of the robot using the classes, and controlling the robot in the execution of alternative work tasks based on the system state. A method for controlling the robot in the above system includes receiving the signals via the controller, classifying the signals using the state classification module, monitoring the present system state of the robot using the classes, and controlling the robot in the execution of alternative work tasks based on the present system state.

  6. Willamette oxygen supplementation studies -- Scale analyses, Dexter water quality parameters, and adult recoveries: Annual progress report, September 30, 1998--September 29, 1999

    International Nuclear Information System (INIS)

    Ewing, R.D.

    1999-01-01

    This report examines the relationship between scale characteristics of returning adults to determine the fork length at which they entered the ocean. These lengths are then related to the length frequencies of fish in the various experimental groups at the time they left the hatchery. This report summarizes the water quality parameters at Dexter Rearing Ponds and presents the complete returns for all experimental groups

  7. Responsiveness of performance-based outcome measures for mobility, balance, muscle strength and manual dexterity in adults with myotonic dystrophy type 1.

    Science.gov (United States)

    Kierkegaard, Marie; Petitclerc, Émilie; Hébert, Luc J; Mathieu, Jean; Gagnon, Cynthia

    2018-02-28

    To assess changes and responsiveness in outcome measures of mobility, balance, muscle strength and manual dexterity in adults with myotonic dystrophy type 1. A 9-year longitudinal study conducted with 113 patients. The responsiveness of the Timed Up and Go test, Berg Balance Scale, quantitative muscle testing, grip and pinch-grip strength, and Purdue Pegboard Test was assessed using criterion and construct approaches. Patient-reported perceived changes (worse/stable) in balance, walking, lower-limb weakness, stair-climbing and hand weakness were used as criteria. Predefined hypotheses about expected area under the receiver operating characteristic curves (criterion approach) and correlations between relative changes (construct approach) were explored. The direction and magnitude of median changes in outcome measures corresponded with patient-reported changes. Median changes in the Timed Up and Go test, grip strength, pinch-grip strength and Purdue Pegboard Test did not, in general, exceed known measurement errors. Most criterion (72%) and construct (70%) approach hypotheses were supported. Promising responsiveness was found for outcome measures of mobility, balance and muscle strength. Grip strength and manual dexterity measures showed poorer responsiveness. The performance-based outcome measures captured changes over the 9-year period and responsiveness was promising. Knowledge of measurement errors is needed to interpret the meaning of these longitudinal changes.

  8. Level of movement skills and dexterity in relation to movement activities of pre-school children in their ordinary lives

    OpenAIRE

    Kubátová, Šárka

    2014-01-01

    and keywords The level of movement skills and dexterity in relation to movement activities of pre- school children in their ordinary lives. The diploma thesis deals with the issue of movement activity of pre-school children. Movement activities are vital part of healthy life, especially for children. It should be an essential part of every activity, no matter if it is sport, game, relaxation or just a walk to school. It should be a common part of every pre-school child daily programme. The ac...

  9. Assessment of Corneal Biomechanical Properties by CorVis ST in Patients with Dry Eye and in Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Qin Long

    2015-01-01

    Full Text Available Purpose. To investigate corneal biomechanical properties in patients with dry eye and in healthy subjects using Corneal Visualization Scheimpflug Technology (CorVis ST. Methods. Biomechanical parameters were measured using CorVis ST in 28 eyes of 28 patients with dry eye (dry eye group and 26 normal subjects (control group. The Schirmer I test value, tear film break-up time (TBUT, and corneal staining score (CSS were recorded for each eye. Biomechanical properties were compared between the two groups and bivariate correlation analysis was used to assess the relationship between biomechanical parameters and dry eye signs. Results. Only one of the ten biomechanical parameters was significantly different between the two groups. Patients in the dry eye group had significantly lower highest concavity time (HC-time (P=0.02 than the control group. Correlation analysis showed a significant negative correlation between HC-time and CSS with marginal P value (ρ=-0.39, P=0.04 in the dry eye group. Conclusions. The corneal biomechanical parameter of HC-time is reduced in dry eyes compared to normal eyes. There was also a very weak but significant negative correlation between HC-time and CSS in the dry eye group, indicating that ocular surface damage can give rise to a more compliant cornea in dry eyes.

  10. Book review: Dexter Hoyos, Mastering the West. Rome and Carthage at War, Oxford-New York, Oxford University Press, 2015, pp. XXI, 337; ISBN 9780199860104

    Directory of Open Access Journals (Sweden)

    Gabriele Demurtas

    2017-11-01

    Full Text Available This essay offers a critical review of the volume by Dexter Hoyos «Mastering the West. Rome and Carthage at War», published in 2015 in Oxford-New York by the Oxford University Press, focused on the conflicts that involved Rome and Carthage between 264 and 146 BC for the supremacy in the western Mediterranean.

  11. The Effects of Sex Hormonal Fluctuations during Menstrual Cycle on Cortical Excitability and Manual Dexterity (a Pilot Study.

    Directory of Open Access Journals (Sweden)

    Maryam Zoghi

    Full Text Available To investigate whether hormonal fluctuations during the menstrual cycle affect corticospinal excitability, intracortical inhibition (ICI or facilitation (ICF in primary motor cortex, and also whether the hormonal fluctuations have any effect on manual dexterity in neurologically intact women.Twenty volunteers (10 Female, 10 Male were included in this study. The levels of progesterone and estradiol were measured from saliva during the women's menstrual follicular, ovulation and mid-luteal phases. Motor evoked potentials were recorded from the right first dorsal interosseous muscle. Single and paired-pulse Transcranial Magnetic Stimulation (TMS were delivered in a block of 20 stimuli. With paired-pulse technique, 3ms and 10ms inter-stimulus intervals were used to assess ICI and ICF, respectively. The Grooved Pegboard Test (GPT was completed in each session before the TMS assessments. Male participants were tested at similar time intervals as female participants.Mixed design ANOVA revealed that GPT score in female participants was significantly lower at the mid-luteal phase compared to the ovulation phase (p = 0.017. However, it was not correlated with progesterone or estrogen fluctuations during the menstrual cycle. The results also showed that the effect of phase, sex and the interaction of phase by sex for resting motor threshold, ICI or ICF were not significant (p > 0.05.Manual dexterity performance fluctuates during the menstrual cycle in neurologically intact women, which might be due to the balance of the neuromodulatory effects of P4 and E2 in the motor cortex during different phases.

  12. So that We Might Become the Righteousness and Justice of God: Re-examining the Gospel in 2 Cor 5:21 for the Church's Contribution to a Better World

    Directory of Open Access Journals (Sweden)

    Ellington, Dustin W.

    2016-12-01

    Full Text Available This article interprets Paul's summary of the gospel in 2 Cor 5:21 as saying that Christ died so that believers might be transformed into God's righteousness (not only deemed as righteous by God. The article explains the powerfully generative nature of God's righteousness and then demonstrates that dikaiosunē also means justice. The interpretation of 2 Cor 5:21 clarifies that the gospel Christians believe for salvation is also a basis of holistic transformation to embody God's righteousness and justice. This enlarged perspective on the gospel supports seamless invitations to put faith in Jesus Christ and to become a force for justice in the world.

  13. Critical Terrorism Studies Since 11 September 2001: What Has Been Learned? Edited by David Miller, Jessie Blackbourn, Rani Dhanda and Helen Dexter. New York, NT: Routledge, 2014.

    Directory of Open Access Journals (Sweden)

    Mark Roberts

    2014-04-01

    Full Text Available Critical Terrorism Studies Since 11 September 2001: What Has Been Learned? Edited by David Miller, Jessie Blackbourn, Rani Dhanda and Helen Dexter. New York, NT: Routledge, 2014. ISBN 978-0-415-83852-8. Graphs. Tables. Sources cited. Index. Pp. viii, 144. $137.75.

  14. Hand-held multi-DOF robotic forceps for neurosurgery designed for dexterous manipulation in deep and narrow space.

    Science.gov (United States)

    Okubo, Takuro; Harada, Kanako; Fujii, Masahiro; Tanaka, Shinichi; Ishimaru, Tetsuya; Iwanaka, Tadashi; Nakatomi, Hirohumi; Sora, Sigeo; Morita, Akio; Sugita, Naohiko; Mitsuishi, Mamoru

    2014-01-01

    Neurosurgical procedures require precise and dexterous manipulation of a surgical suture in narrow and deep spaces in the brain. This is necessary for surgical tasks such as the anastomosis of microscopic blood vessels and dura mater suturing. A hand-held multi-degree of freedom (DOF) robotic forceps was developed to aid the performance of such difficult tasks. The diameter of the developed robotic forceps is 3.5 mm, and its tip has three DOFs, namely, bending, rotation, and grip. Experimental results showed that the robotic forceps had an average needle insertion force of 1.7 N. Therefore, an increase in the needle insertion force is necessary for practical application of the developed device.

  15. Geospatial Data Quality of the Servir CORS Network

    Science.gov (United States)

    Santos, J.; Teodoro, R.; Mira, N.; Mendes, V. B.

    2015-08-01

    The SERVIR Continuous Operation Reference Stations (CORS) network was implemented in 2006 to facilitate land surveying with Global Navigation Satellite Systems (GNSS) positioning techniques. Nowadays, the network covers all Portuguese mainland. The SERVIR data is provided to many users, such as surveyors, universities (for education and research purposes) and companies that deal with geographic information. By middle 2012, there was a significant change in the network accessing paradigm, the most important of all being the increase in the responsibility of managing the network to guarantee a permanent availability and the highest quality of the geospatial data. In addition, the software that is used to manage the network and to compute the differential corrections was replaced by a new software package. These facts were decisive to perform the quality control of the SERVIR network and evaluate positional accuracy. In order to perform such quality control, a significant number of geodetic monuments spread throughout the country were chosen. Some of these monuments are located in the worst location regarding the network geometry in order to evaluate the accuracy of positions for the worst case scenarios. Data collection was carried out using different GNSS positioning modes and were compared against the benchmark positions that were determined using data acquired in static mode in 3-hour sessions. We conclude the geospatial data calculated and provided to the users community by the network is, within the surveying purposes, accurate, precise and fits the needs of those users.

  16. Test re-test reliability and construct validity of the star-track test of manual dexterity

    DEFF Research Database (Denmark)

    Kildebro, Niels; Amirian, Ilda; Gögenur, Ismail

    2015-01-01

    Objectives. We wished to determine test re-test reliability and construct validity of the star-track test of manual dexterity. Design. Test re-test reliability was examined in a controlled study. Construct validity was tested in a blinded randomized crossover study. Setting. The study was performed...... at a university hospital in Denmark. Participants. A total of 11 subjects for test re-test and 20 subjects for the construct validity study were included. All subjects were healthy volunteers. Intervention. The test re-test trial had two measurements with 2 days pause in between. The interventions...... in the construct validity study included baseline measurement, intervention 1: fatigue, intervention 2: stress, and intervention 3: fatigue and stress. There was a 2 day pause between each intervention. Main outcome measure. An integrated measure of completion time and number of errors was used. Results. All...

  17. Quantitative evaluation of right ventricular overload in cor pulmonale using sup 201 Tl myocardial SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Hiroshi; Misawa, Toshihiro; Kutsumi, Yasunori [Fukui Medical School, Matsuoka (Japan); and others

    1991-01-01

    To determine quantitatively the discriminant and characteristics of cor pulmonale, {sup 201}Tl myocardial perfusion SPECT was performed in 16 patients with chronic obstructive pulmonary disease (COPD) and 7 with restrictive pulmonary disease (RPD). One section of the short-axis SPECT image in which the right ventricle was most clearly visualized was selected. Tl-score was defined as the ratio of the sum of counts in the region of interest (ROI) at the anterior, mid, and posterior regions of the right ventricular free wall to the sum of counts in ROI at the posterior, lateral, and anterior walls of the left ventricle, and the anterior and posterior regions of the interventricular septum. In the group of COPD patients, Tl-score was positively correlated with mean pulmonary arterial pressure (mPAP), total pulmonary vascular resistance (TPR), and arterial carbon dioxide tension (PaCO{sub 2}), while it was inversely correlated with arterial oxygen tension (PaO{sub 2}). However, there was no significant correlation between Tl-score and mPAP, TPR, PaCO{sub 2}, and PaO{sub 2} in the group of RPD patients. In assessing pulmonary hypertension as defined by mPAP over 20 mmHg, a Tl-score greater than 0.25 was useful with a sensitivity of 69% and a specificity of 90%. The occurrence of cor pulmonale is a major factor in determining the prognosis of COPD patients. It was concluded that {sup 201}Tl myocardial SPECT is useful for evaluating right ventricular overload quantitatively, as well as for assessing core pulmonale, especially in COPD patients, since the ratio of Tl counts in the right and left ventricles was significantly correlated with right cardiopulmonary hemodynamic parameters. (N.K.).

  18. Evaluation of radioimmunoassay for renal functions in senile patients with cor pulmonale without respiratory failure

    International Nuclear Information System (INIS)

    Fu Benqi; Chen Mingxi; Zhou Gangyi; Zhang Zhengzhong

    1995-01-01

    The results of RIA about serum β 2 -MG and urine β 2 -MG, Alb, IgG in the senile patients with cor pulmonale are reported. The contents of sβ 2 -MG, uβ 2 -MG, uAlb in non-respiratory failure group are higher than that of the control group. The contents of sβ 2 -MG, uβ 2 -MG, uAlb and uIgG in the respiratory failure group are higher than that of the non-respiratory failure group. The results show that the renal glamorous and renal tubules functions are slightly damaged in non-respiratory failure group, while functions of the respiratory failure group become worse

  19. Association of remote dexterity and remote lifting for maintenance in fuel reprocessing industry

    International Nuclear Information System (INIS)

    Streiff, G.; Auchapt, P.; Vertut, J.

    1984-01-01

    The MA23M is an articulated bilateral servomanipulator with theoretically unlimited distance between master and slave stations. The last developments being carried on enable its good utilization in the large cells that will exist in the next reprocessing plants. Recent developments concerning computer aided operations like automatic TV tracking of the effector and manipulative assistance of MA23 and transporter enable realistic application in the large cells of the future reprocessing plants. In another hand manipulator containment, transfer and maintenance, in a glove box have been demonstrated. Concerning the in-cell process equipment to be maintained, extensive testing has shown that the association with a hoist is an excellent trade off in power and dexterity enabling solution of practically all expected or unexpected operations. According to the in-cell machinery and to the difficulty of the operation, one or two dextrous arms can be associated with one hoist. Dismantling of machines or dismantling of the whole facility will be possible by developing special tooling handled by the dextrous manipulator or, if too heavy, oriented by the manipulator but suspended to the hoist

  20. Efeito de diferentes fotopolimerizadores e meio de imersão na rugosidade e na cor de um compósito nanoparticulado

    Directory of Open Access Journals (Sweden)

    Suéllen Campos PLASTER

    Full Text Available Resumo Introdução O consumo excessivo de refrigerantes parece alterar as propriedades dos compósitos e essa alteração pode estar relacionada à unidade fotopolimerizadora. Objetivo Avaliar a alteração da rugosidade superficial (ΔR e da cor (ΔE de um compósito polimerizado por diferentes fotopolimerizadores, imerso em água destilada ou Coca-Cola®. Metodologia Sessenta amostras da resina nanoparticulada (FiltekMR Z350 XT, 3M foram distribuídas de acordo com as diferentes unidades de fotopolimerização: a luz halógena de quartzo-tungstênio-halogênio (QTH; b Luz de Emissão Diodo - LED 1 com ponteira de polímero; c LED 2 com ponteira de fibra ótica. Metade de cada grupo (n=10 foi mantida em água destilada ou imersa em Coca-Cola® 2×/dia por 20 minutos, durante 14 dias. Os dados foram submetidos aos testes Mann-Whitney e Kruskal-Wallis (p≤0,05. Resultado A ΔR não foi significante entre os grupos: em água: QTH = 0,006; LED 1 = 0,019; LED 2 = 0,010 (p=0,33; em refrigerante: QTH = 0,021; LED 1= 0,011; LED 2 = 0,030 (p=0,86. A ΔE não foi significativa entre os fotopolimerizadores: em água: QTH = 1,40; LED 1 = 1,80; LED 2 = 1,60 (p=0,31; em refrigerante: QTH = 2,51; LED 1= 1,91; LED 2 = 2,61 (p=0,41, mas foi significante comparando os meios de imersão (p=0,01, exceto para LED 1 (p=0,54. Conclusão As unidades fotopolimerizadoras não interferiram na rugosidade superficial e na cor da resina composta nanoparticulada. Os mergulhos diários em refrigerante não alteraram a lisura, mas alteraram a cor de modo visualmente perceptível, mas clinicamente aceitável, conforme os parâmetros da literatura científica.

  1. ANÁLISIS PRAGMALINGÜÍSTICO DE 1 Cor 9, 24-27. El deporte en perspectiva paulina

    OpenAIRE

    Bolaño Mercado, Tomas Emilio

    2011-01-01

    El análisis semántico, narrativo, y pragmático de 1 Cor 9, 24-27 realizado sobre el Textus receptus que trae la Greek New Testament apoyado en la traducción literal de Lacueva y la versión dinámica de la Nueva Biblia Española, precedido de una contextualización literaria y del sitz in lemebem expone el uso que San Pablo hace del lenguaje deportivo de los Juegos Ístmicos para exhortar de modo comparativo a la disciplina cristiana. El posterior uso pragmático que la tradición de la Iglesia hizo...

  2. Cenas da circulação: fragmentos de uma etnografia sobre homossexualidade, gênero, cor e mestiçagem em uma favela do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Silvia Aguião

    Full Text Available Este artigo expõe parte de uma etnografia desenvolvida na favela de Rio das Pedras com enfoque orientado para questões relacionadas à sexualidade, gênero, cor/raça e mestiçagem. Localizada na cidade do Rio de Janeiro, a favela é reconhecida por duas características particulares: a ausência do tráfico armado de drogas e a intensa imigração nordestina. A partir de algumas cenas recortadas do trabalho de campo, busca-se explorar como estes aspectos imprimem conformações específicas às experiências e às representações sobre homossexualidade, gênero e cor/raça, procurando observar como a interseção destes aspectos relaciona-se a processos de diferenciação social e perpassa estruturas e hierarquias sociais nesse espaço.

  3. Cor, betacaroteno e colesterol em gema de ovos obtidos de poedeiras que receberam diferentes dietas Color, beta-caroten and cholesterol in yolks of eggs by different diets of laying hens

    Directory of Open Access Journals (Sweden)

    Luciana Marino e Biscaro

    2006-12-01

    Full Text Available O ovo é um alimento considerado nutricionalmente completo, e contém quantidade significativa de nutrientes. Para os consumidores, a qualidade deste alimento está relacionada com o prazo de validade do produto e com as características sensoriais, como cor da gema e da casca. Poucos estudos foram efetuados no Brasil sobre a utilização de agentes pigmentantes e seus efeitos sobre a coloração das gemas e proporção e qualidade química dos componentes do ovo. Com base nisso, objetivou-se com este trabalho relacionar diferentes dietas com cor, quantidade de betacaroteno e teor colesterol das gemas dos ovos. Foram coletados ovos de poedeiras que receberam 4 diferentes tipos de ração. A cor foi medida em colorímetro Minolta, o beta-caroteno separado em coluna e medido em espectrofotômetro e o colesterol extraído com clorofórmio e quantificado por método colorimétrico. Os resultados mostraram que não há relação entre a cor e aumento do teor de betacaroteno das gemas dos ovos, mas a alimentação alterou a cor da gema. O teor de colesterol foi diferente (pEgg is a nutritional complete food, and content significant quantity of nutrients. For the consumers, the food quality is related with validity date of product and with sensorial characteristics, like yolk color and hull. Few studies were done in Brazil about utilization of colorfull agents and theirs effects in yolk color and chemical quality of egg compounds. The objective of this research was related different feeds with the color, beta-carotene and cholesterol amount of egg yolk. Eggs were caught of laying hens that received 4 feed types. The color measure was done by Minolta colorimeter, beta-carotene separated by column and spectrophotometer and cholesterol separated with chloroform and measured by colorimetric method. The results showed that there is not a relation between the color an increase of beta-carotene amount in the yolks, but feed altered the yolk color. Cholesterol

  4. Pawedness Trait Test (PaTRaT—A New Paradigm to Evaluate Paw Preference and Dexterity in Rats

    Directory of Open Access Journals (Sweden)

    Ana M. Cunha

    2017-10-01

    Full Text Available In rodents, dexterity is commonly analyzed in preference paradigms in which animals are given the chance to use either the left or the right front paws to manipulate food. However, paw preference and dexterity at population and individual levels are controversial as results are incongruent across paradigms. We have therefore developed a semi-quantitative method—the pawdeness trait test (PaTRaT—to evaluate paw preference degree in rats. The PaTRaT consists in a classification system, ranging from +4 to −4 where increasingly positive and negative values reflect the bias for left or right paw use, respectively. Sprague-Dawley male rats were confined into a metal rectangular mesh cylinder, from which they can see, smell and reach sugared rewards with their paws. Due to its size, the reward could only cross the mesh if aligned with its diagonal, imposing additional coordination. Animals were allowed to retrieve 10 rewards per session in a total of four sessions while their behavior was recorded. PaTRaT was repeated 4 and 8 weeks after the first evaluation. To exclude potential bias, rats were also tested for paw fine movement and general locomotion in other behavioral paradigms as well as impulsivity (variable delay-to-signal, VDS, memory and cognitive flexibility (water maze. At the population level 54% of the animals presented a rightward bias. Individually, all animals presented marked side-preferences, >2 and <−2 for left- and right-sided bias, respectively, and this preference was stable across the three evaluations. Inter-rater consistency was very high between two experienced raters and substantial when two additional inexperienced raters were included. Left- and right-biased animals presented no differences in the ability to perform fine movements with any of the forelimbs (staircase and general locomotor performance. Additionally, these groups performed similarly in executive function and memory tasks. In conclusion, PaTRaT is able

  5. Comparison between core temperatures measured telemetrically using the CorTemp® ingestible temperature sensor and rectal temperature in healthy Labrador retrievers.

    Science.gov (United States)

    Osinchuk, Stephanie; Taylor, Susan M; Shmon, Cindy L; Pharr, John; Campbell, John

    2014-10-01

    This study evaluated the CorTemp(®) ingestible telemetric core body temperature sensor in dogs, to establish the relationship between rectal temperature and telemetrically measured core body temperature at rest and during exercise, and to examine the effect of sensor location in the gastrointestinal (GI) tract on measured core temperature. CorTemp(®) sensors were administered orally to fasted Labrador retriever dogs and radiographs were taken to document sensor location. Core and rectal temperatures were monitored throughout the day in 6 resting dogs and during a 10-minute strenuous retrieving exercise in 6 dogs. Time required for the sensor to leave the stomach (120 to 610 min) was variable. Measured core temperature was consistently higher than rectal temperature across all GI locations but temperature differences based on GI location were not significant (P = 0.5218). Resting dogs had a core temperature that was on average 0.4°C above their rectal temperature with 95% limits of agreement (LoA) between 1.2°C and -0.5°C. Core temperature in exercising dogs was on average 0.3°C higher than their concurrent rectal temperature, with LoA of +1.6°C and -1.1°C.

  6. Proteinas do liquido cefalorraqueano: II. Valores normais das frações proteicas obtidas por eletroforese (variações ligadas a cor, sexo e idade

    Directory of Open Access Journals (Sweden)

    Lucia M. Singer Vermes

    1983-03-01

    Full Text Available Mediante dosagens de proteínas totais e eletroforese sobre acetato de celulose de 213 amostras de LCR normal, obtidas por punção da cisterna magna, foram efetuados estudos para verificação de variações ligadas à cor, sexo e idade. Os resultados obtidos permitiram concluir que: 1. não existem diferenças ligadas à cor no proteinograma do LCR; 2. em crianças, os fatores sexo e idade não influem nos valores estudados; 3. as taxas de proteínas totais e frações protéicas do LCR normal de criança diferem das de homens e de mulheres; 4. em adultos ocorrem variações ligadas ao sexo no proteinograma do LCR; 5. em adultos, proteínas totais e todas frações protéicas, quando expressas em mg/100 ml, aumentam com o avançar da idade. Foram estabelecidas, para a metodologia usada, as taxas fisiológicas do proteinograma do LCR de crianças, homens e mulheres, separadamente.

  7. Considerations for SphygmoCor radial artery pulse wave analysis: side selection and peripheral arterial blood pressure calibration.

    Science.gov (United States)

    Martin, Jeffrey S; Borges, Alexandra R; Christy, John B; Beck, Darren T

    2015-10-01

    Methods employed for pulse wave analysis (PWA) and peripheral blood pressure (PBP) calibration vary. The purpose of this study was to evaluate the agreement of SphygmoCor PWA parameters derived from radial artery tonometry when considering (1) timing (before vs. after tonometry) and side selection (ipsilateral vs. contralateral limb) for PBP calibration and (2) side selection for tonometry (left vs. right arm). In 34 subjects (aged 21.9 ± 2.3 years), bilateral radial artery tonometry was performed simultaneously on three instances. PBP assessment via oscillometric sphygmomanometry in the left arm only and both arms simultaneously occurred following the first and second instances of tonometry, respectively. Significant within arm differences in PWA parameters derived before and after PBP measurement were observed in the right arm only (for example, aortic systolic blood pressure, Δ=0.38 ± 0.64 mm Hg). Simultaneously captured bilateral PWA variables demonstrated significant between arm differences in 88% (14/16) and 56% (9/16) of outcome variables when calibrated to within arm and equivalent PBP, respectively. Moreover, the right arm consistently demonstrated lower values for clinical PWA variables (for example, augmentation index, bias=-2.79%). However, 26% (n=9) of participants presented with clinically significant differences (>10 mm Hg) in bilateral PBP and their exclusion from analysis abolished most between arm differences observed. SphygmoCor PWA in the right radial artery results in greater variability independent of the timing of PBP measurement and magnitude of calibration pressures in young subjects. Moreover, bilateral PBP measurement is imperative to identify subjects in whom a significant difference in bilateral PWA outcomes may exist.

  8. Termoterapia transpupilar em melanoma maligno da coróide Transpupillary thermotherapy for malignant choroidal melanoma

    Directory of Open Access Journals (Sweden)

    Martha M. Motomo Chojniak

    2001-04-01

    Full Text Available Objetivo: Vários métodos vem sendo utilizados para o tratamento dos melanomas da coróide. A proposta deste trabalho preliminar é avaliar a eficácia da termoterapia transpupilar (TTT como tratamento primário de melanomas da coróide pequenos. Métodos: Foi realizado um trabalho prospectivo e não-randomizado para avaliar os aspectos clínicos, resposta do tumor, complicações e resultados visuais de pacientes portadores de melanomas da coróide pequenos (até 4,0 mm de espessura e 12 mm de diâmetro basal tratados por termoterapia transpupilar utilizando-se sucessivas aplicações de laser diodo contínuo de 810 nm. Resultados: Foram tratados 11 pacientes portadores de melanomas da coróide pequenos. O tumor era único e pigmentado em 100% dos casos. Crescimento documentado esteve presente em 5 pacientes (45,45% previamente ao tratamento e fatores de risco para crescimento ou metástase estavam presentes em todos os pacientes. O tempo de seguimento destes pacientes a partir do tratamento foi em média de 5,72 meses (3 - 8 meses. Foram utilizadas 3 sessões de laser em 5 pacientes (45,45% e 4 sessões em 6 pacientes (64,64%. As lesões apresentavam, por ocasião do diagnóstico, uma espessura média de 2,65 mm (1,85-3,86 mm, com maior diâmetro basal médio de 7,98 mm (4,2-11,33 mm. Após o tratamento, a espessura média foi de 1,83 mm (0,98-2,93 mm e o maior diâmetro basal médio foi de 6,59 mm (3,81 mm -10,67 mm. Das lesões tratadas, 100% apresentaram diminuição da altura e do máximo diâmetro basal, tendo sido a diminuição média da espessura de 0,89 mm e do máximo diâmetro basal de 1,39 mm. A acuidade visual manteve-se inalterada em 5 casos (45,45% e piorou após o tratamento em 6 casos (54,54%. Ocorreram complicações em 9 casos, tendo sido considerada complicação grave 1 caso de descolamento parcial da retina (9,09%; as outras complicações foram consideradas leves: pequenas hemorragias intra-retinianas em 7 pacientes (63

  9. Color change using HSB color system of dental resin composites immersed in different common Amazon region beverages Alteração de cor de resinas compostas imersas em diferentes bebidas comuns da região Amazônica, utilizando o sistema de cor HSB

    Directory of Open Access Journals (Sweden)

    Débora da Costa e Silva

    2009-01-01

    Full Text Available The purpose of this study is to evaluate in vitro the color stability of composite resins when exposed to beverages with high coloring contents from the Amazon region. 240 samples from four different composite brands (Natural Look, Z350, 4Seasons and Opallis of hue A3 were fabricated using an acrylic matrix. The samples were stored in distilled water at 37ºC for 24 hours. The initial color (T0 was registered using a Canon EOS Rebel XTi 10 mp camera, and then the samples were divided into four groups (n=15: G1 (coffee, G2 (açaí juice, G3 (energetic guaraná and G4 (control - distilled water. The samples were exposed to solutions of DES (6hs and RE (18hs and placed in a double boiler under constant agitation, at 37ºC for 30 days. The samples were immersed in the coloring solutions for 15 minutes daily. After 7, 15 and 30 days, new photographic registers were made (T1, T2 and T3. The images were analyzed using Corel PHOTO-PAINT 12 software to identify the colors through the HSB system. The Kruskal-Wallis and t tests (pEste estudo propôs avaliar in vitro a estabilidade de cor de alguns compósitos quando expostos a bebidas da Região Amazônica com alto teor de corante. Foram confeccionados 240 corpos de prova (CP de quatro resinas (Natural Look, Z350, 4Seasons e Opallis no matiz A3 utilizando uma matriz de acrílico. As amostras foram armazenadas em água deionizada a 37ºC por 24 horas. A cor inicial das resinas (T0 foi registrada utilizando a máquina Canon EOS Rebel XTi 10Mp, e em seguida os CP foram divididos em 4 grupos (n=15: G1 (café, G2 (suco de açaí, G3 (guaraná energético e G4 (controle - água destilada. Os CP foram submetidos às soluções DES (6hs e RE (18hs e colocados em banho-maria, sob constante agitação, à temperatura de 37ºC durante 30 dias. Diariamente os corpos de prova foram imersos nas soluções corantes durante 15 minutos. Após 7, 15 e 30 dias realizaram-se novos registros fotográficos (T1, T2 e T3. As

  10. Redução de cor ICUMSA em soluções concentradas de açúcar bruto por processo oxidativo com peróxido de hidrogênio

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    Juliana Lorenz Mandro

    2017-05-01

    Full Text Available Resumo A clarificação/purificação do açúcar refinado a partir de açúcares brutos, como Very High Polarization (VHP, é realizada atualmente pelo uso de resinas de troca-iônica ou carvão ativado. No entanto, são metodologias de alto custo, que necessitam de constante regeneração/recuperação e apresentam perda de capacidade em função do tempo de processamento. Neste sentido, estudos sobre tecnologias alternativas ao uso de resinas de troca-iônica e carvão ativado vêm sendo cada vez mais relacionados, para aumentar a economia do setor. O peróxido de hidrogênio em solução comercial (35%, v/v pode também ser entendido como agente promotor de redução de cor ICUMSA, na cadeia produtiva do açúcar refinado. Com isso, foram realizados tratamentos a fim de testar a eficiência do agente oxidante na clarificação de açúcar bruto do tipo VHP. Os tratamentos foram avaliados frente a diferentes doses de peróxido de hidrogênio, pH e temperaturas, durante um tempo reacional de uma hora. Todas as amostras tratadas apresentaram redução de cor ICUMSA, sendo que o maior decréscimo esteve na faixa de 67 a 70%. O aumento da dose de agente oxidante foi proporcional ao aumento de precipitados no meio, em que o tratamento com maior concentração de peróxido de hidrogênio apresentou índice de turbidez de 142 NTU em relação ao valor da amostra bruta (17 NTU, sendo o ensaio com maior turbidez. A degradação de sacarose ocorreu de forma mais pronunciada nos tratamentos com valores de pH abaixo de 5,0. Com isso, o peróxido de hidrogênio se mostrou uma alternativa viável para redução de cor ICUMSA e precipitação de não-açúcares e os tratamentos com melhor redução de cor também não foram críticos na degradação de sacarose.

  11. Effects of transcranial direct current stimulation on the control of finger force during dexterous manipulation in healthy older adults.

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    Pranav J Parikh

    Full Text Available The contribution of poor finger force control to age-related decline in manual dexterity is above and beyond ubiquitous behavioral slowing. Altered control of the finger forces can impart unwanted torque on the object affecting its orientation, thus impairing manual performance. Anodal transcranial direct current stimulation (tDCS over primary motor cortex (M1 has been shown to improve the performance speed on manual tasks in older adults. However, the effects of anodal tDCS over M1 on the finger force control during object manipulation in older adults remain to be fully explored. Here we determined the effects of anodal tDCS over M1 on the control of grip force in older adults while they manipulated an object with an uncertain mechanical property. Eight healthy older adults were instructed to grip and lift an object whose contact surfaces were unexpectedly made more or less slippery across trials using acetate and sandpaper surfaces, respectively. Subjects performed this task before and after receiving anodal or sham tDCS over M1 on two separate sessions using a cross-over design. We found that older adults used significantly lower grip force following anodal tDCS compared to sham tDCS. Friction measured at the finger-object interface remained invariant after anodal and sham tDCS. These findings suggest that anodal tDCS over M1 improved the control of grip force during object manipulation in healthy older adults. Although the cortical networks for representing objects and manipulative actions are complex, the reduction in grip force following anodal tDCS over M1 might be due to a cortical excitation yielding improved processing of object-specific sensory information and its integration with the motor commands for production of manipulative forces. Our findings indicate that tDCS has a potential to improve the control of finger force during dexterous manipulation in older adults.

  12. Risco para transtornos alimentares em escolares de Salvador, Bahia, e a dimensão raça/cor

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    Liliane de Jesus Bittencourt

    2013-10-01

    Full Text Available OBJETIVO: Estimar a existência de fatores de risco associados aos transtornos alimentares em escolares da cidade de Salvador, Bahia, por meio da dimensão étnico-racial como fator de heterogeneidade. MÉTODOS: Os participantes da pesquisa são escolares do sexo feminino, na faixa etária entre 15 e 30 anos, residentes na cidade de Salvador, no Estado da Bahia. Foram investigadas 626 estudantes, selecionadas em instituições públicas e privadas de ensino médio e universitário. Utilizaram-se o Eating Atittude Test-26, o Body Shape Questionnaire e o Beck Depression Inventory como instrumentos de identificação de risco para os transtornos alimentares. A classificação étnico-racial se deu por autodeclaração, de acordo com as categorias do Instituto Brasileiro de Geografia e Estatística. Foram realizadas análises descritivas, bivariadas (χ2 de Pearson e regressão logística multivariada para análise dos dados. RESULTADOS: As estudantes que se identificaram como amarelas ou indígenas têm 3,6 vezes mais chances de desenvolverem comportamentos alimentares desordenados e 4,8 vezes mais possibilidade de estarem insatisfeitas com sua imagem corporal. As pardas apresentam 2,5 vezes mais risco para essa insatisfação. A depressão é uma comorbidade que deve ser considerada, apesar de não estar associada significativamente à raça/cor. CONCLUSÃO: As mulheres não brancas em Salvador apresentam risco de desenvolver transtornos alimentares. Outros estudos que combinam métodos quantitativos e qualitativos podem permitir uma análise mais robusta quanto à relação entre transtornos alimentares e raça/cor e etnia.

  13. Computation of Estonian CORS data using Bernese 5.2 and Gipsy 6.4 softwares

    Science.gov (United States)

    Kollo, Karin; Kall, Tarmo; Liibusk, Aive

    2017-04-01

    GNSS permanent station network in Estonia (ESTREF) was established already in 2007. In 2014-15 extensive reconstruction of ESTREF was carried out, including the establishment of 18 new stations, change of the hardware in CORS stations as well as establishing GNSS-RTK service for the whole Estonia. For GNSS-RTK service one needs precise coordinates in well-defined reference frame, i.e., ETRS89. For long time stability of stations and time-series analysis the re-processing of Estonian CORS data is ongoing. We re-process data from 2007 until 2015 with program Bernese GNSS 5.2 (Dach, 2015). For the set of ESTREF stations established in 2007, we perform as well computations with GIPSY 6.4 software (Ries et al., 2015). In the computations daily GPS-only solution was used. For precise orbits, final products from CODE (CODE analysis centre at the Astronomical Institute of the University of Bern) and JPL (Jet Propulsion Laboratory) for Bernese and GIPSY solutions were used, respectively. The cut-off angle was set to 10 degrees in order to avoid near-field multipath influence. In GIPSY, precise point positioning method with fixing ambiguities was used. Bernese calculations were performed based on double difference processing. Antenna phase centers were modelled based on igs08.atx and epnc_08.atx files. Vienna mapping function was used for mapping tropospheric delays. For the GIPSY solution, the higher order ionospheric term was modelled based on IRI-2012b model. For the Bernese solution higher order ionospheric term was neglected. FES2004 ocean tide loading model was used for the both computation strategies. As a result, two solutions using different scientific GNSS computation programs were obtained. The results from Bernese and GIPSY solutions were compared, using station repeatability values, RMS and coordinate differences. KEYWORDS: GNSS reference station network, Bernese GNSS 5.2, Gipsy 6.4, Estonia. References: Dach, R., S. Lutz, P. Walser, P. Fridez (Eds); 2015

  14. The Effects of Listening to Persian Music on the Hand Dexterity and Depression in a Patient with Stroke: A Case Report

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    Reyhaneh Maktoufi

    2015-09-01

    Full Text Available Introduction: Nowadays the use of music therapy for neurological disorders in developed countries is widely emphasized. Despite this, there is little scientific evidence regarding the use of this method for the treatment of Iranian patients with stroke. Case report: Since Iranian patients are more familiar with Persian music, this study was performed to describe the effects of listening to the Persian music played with Daf (an Iranian music instrument in a 54-year-old man with chronic stroke. Discussion: This case report could show for the first time, the positive effect of passive listening to Persian music with Iranian Daf instrument on the hand dexterity and depression in a patient with chronic stroke.

  15. Cold acclimation induces distinctive changes in the chromatin state and transcript levels of COR genes in Cannabis sativa varieties with contrasting cold acclimation capacities.

    Science.gov (United States)

    Mayer, Boris F; Ali-Benali, Mohamed Ali; Demone, Jordan; Bertrand, Annick; Charron, Jean-Benoit

    2015-11-01

    Little is known about the capacity of Cannabis sativa to cold-acclimate and develop freezing tolerance. This study investigates the cold acclimation (CA) capacity of nine C. sativa varieties and the underlying genetic and epigenetic responses. The varieties were divided into three groups based on their contrasting CA capacities by comparing the survival of non-acclimated and cold-acclimated plants in whole-plant freeze tests. In response to the CA treatment, all varieties accumulated soluble sugars but only the varieties with superior capacity for CA could maintain higher levels throughout the treatment. In addition, the varieties that acclimated most efficiently accumulated higher transcript levels of cold-regulated (COR) genes and genes involved in de novo DNA methylation while displaying locus- and variety-specific changes in the levels of H3K9ac, H3K27me3 and methylcytosine (MeC) during CA. Furthermore, these hardy C. sativa varieties displayed significant increases in MeC levels at COR gene loci when deacclimated, suggesting a role for locus-specific DNA methylation in deacclimation. This study uncovers the molecular mechanisms underlying CA in C. sativa and reveals higher levels of complexity regarding how genetic, epigenetic and environmental factors intertwine. © 2014 Scandinavian Plant Physiology Society.

  16. Deconstruyendo a Dexter. Microanálisis y reinterpretación de una serie televisiva en la web

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    Rafael Marfil Carmona

    2011-04-01

    Full Text Available El presente artículo expone, de forma resumida, un planteamiento metodológico para analizar producciones audiovisuales, aportando un ejemplo concreto de las posibilidades que ofrece la web para finalizar ese proceso a través de la expresión creativa. Se propone una metodología integradora aplicable, en el caso aportado, a un ejercicio de microanálisis de la secuencia introductoria a la serie de televisión Dexter (M. Cuesta, T. Goldwyn y R. Lieberman; Showtime television, 2006, mostrando finalmente un interesante ejemplo de reinterpretación en la web, como es el remake titulado Malviviendo (malviviendo.com, ejemplo del uso del lenguaje audiovisual y los nuevos medios de difusión (youtube e internet TV como fase final de un proceso conceptual-creativo. El recorrido analítico parte de una reflexión conceptual y crítica para finalizar en la expresión a través de los propios medios audiovisuales.

  17. Influence of color on acceptance and identification of flavor of foods by adults Influência da cor na aceitação e identificação do sabor dos alimentos por adultos

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    Nayane Aparecida Araújo Dias

    2012-06-01

    Full Text Available The sensory characteristics color and flavor of food play an important role not only in the selection, but also in the determination of consumption, satiation, and ingestion. With the objective to determine and evaluate the influence of color on the acceptance and identification of flavor of foods for adults, sensory analysis was performed on jellies by non-trained tasters of both sexes aged between 18 and 60 years (1750 tests. A hedonic scale and combinations of five colors (red, yellow, green, blue and purple and three flavors (strawberry, pineapple, and limes were used in the acceptance test totaling 15 samples. In the duo-trio discrimination test, together with the reference sample (R, one sample identical to the reference and another of identical color and different flavor were offered, and the judges were requested to identify the sample that was different from the reference sample. The colors used did not influence the acceptance of the samples (P > 0.05, and as there was not significant interaction between color and flavor. However, the limes flavor negatively influenced acceptance when compared to the other flavors. With regard to flavor differentiation, the colors used did not influence flavor identification (P > 0.05; However, differentiated behavior was identified between females and males, and the latter were more error-prone. Therefore, under the experimental conditions tested, color did not influence the acceptance and identification of the flavor of the samples by adults.As características sensoriais cor e sabor dos alimentos desempenham papel importante não somente na seleção, como também na determinação do consumo, ingestão e saciedade. Objetivando determinar e avaliar a influência da cor na aceitação e identificação do sabor dos alimentos por adultos, foram realizados testes de análise sensorial com gelatinas por provadores não treinados, de ambos os gêneros, com idade entre 18 e 60 anos (1750 provas. No teste

  18. Cor de feijão vagem fresco e processado após aplicação de cálcio Color of fresh and processed snap bean pods after calcium application

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    Simone Palma Fávaro

    2000-09-01

    Full Text Available A cor em vegetais é um dos principais atributos de qualidade observado pelo consumidor e é influenciada por características intrínsecas e de processamento. O objetivo desta investigação foi avaliar as alterações de cor de feijão vagem fresco e processado após aplicação de concentrações crescentes de cálcio via absorção radicular. O feijão vagem cultivar UEL 1 foi cultivado com aplicação de concentrações crescentes de cálcio via solução nutritiva contendo 0, 75 , 150 e 300 mL L-1 de cálcio em substrato de areia grossa. A cor das vagens ao natural e enlatadas foram avaliadas por colorimetria de três estímulos, e os resultados foram expressos no sistema Hunter. As vagens ao natural apresentaram-se mais claras e amarelas quando foi adicionado cálcio à solução nutritiva. O calor empregado no processo de enlatamento teve efeito pronunciado na redução da luminosidade e na cor verde, mesmo com o aumento na quantidade de cálcio nas vagens.The color in vegetables is one of the main quality attributes observed by the consumer and it is influenced by intrinsic characteristics and canning process. This research meant to investigate the effect of increasing calcium concentrations applied to a nutrient solution on physical measurements of the color of snap bean pods.This experiment was carried out wtih the cultivar UEL 1 grown in coarse sand with nutrient solution supplied at the following levels of calcium: 0, 75, 150 and 300 mL L-1. Fresh pods were analysed for calcium content. The fresh and canned pods were evaluated for color with tristimulus colorimetry and data were expressed according to the Hunter system. The fresh pods were lighter and yellowisher when calcium was added to the nutrient solution. The heat used for the canning process had a significant effect on reducing lightness and greeness, even with the greater amounts of calcium in the pods.

  19. Alterações oxidativas (cor e lipídios em presunto de peru tratado por Alta Pressão Hidrostática (APH

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    Simone Pereira Mathias

    2010-12-01

    Full Text Available A Alta Pressão Hidrostática (APH consiste em uma tecnologia inovadora de processamento de alimentos com utilização de pressões elevadas (100 a 900 MPa que possui vantagens em relação às tecnologias térmicas convencionais, pois mantém as características sensoriais do alimento próximas do original e garante segurança do ponto de vista microbiológico, por prolongado período de vida útil. No presente estudo, foi avaliada a aplicação de alta pressão a presunto de peru nos processos oxidativos, em particular na oxidação de lipídios e os efeitos na cor do produto, quando tratados a pressões de 200 a 400 MPa, por 5, 10 e 15 minutos em temperatura ambiente. Dos resultados obtidos, pode-se observar que não foram verificadas diferenças significativas (p > 0,05 entre amostras controle e pressurizada para o índice de TBA e índice de peróxido. Foi observado também alteração da cor decorrente de reações oxidativas aos 45 e 65 dias de armazenamento em amostras tratadas com pressões de 400 MPa a 5 e 15 minutos

  20. Investigating Astromaterials Curation Applications for Dexterous Robotic Arms

    Science.gov (United States)

    Snead, C. J.; Jang, J. H.; Cowden, T. R.; McCubbin, F. M.

    2018-01-01

    a curator; other potential future returned samples may require cryogenic curation. Robot arms may be combined with high resolution cameras within a sample cabinet and controlled remotely by curator. Sophisticated robot arm and hand combination systems can be programmed to mimic the movements of a curator wearing a data glove; successful implementation of such a system may ultimately allow a curator to virtually operate in a nitrogen, cryogenic, or biologically sensitive environment with dexterity comparable to that of a curator physically handling samples in a glove box.

  1. Quem é Dexter Morgan? A questão da identidade e da ética presentes em uma série de televisão

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    Rubens Francisco Torres

    2010-10-01

    Full Text Available Dexter é um seriado americano que mostra a vida de um serial killer que mata outros assassinos. Nessa série estão presentes muitos temas filosóficos importantes, como a busca pela identidade pessoal, o valor da ética, e quais as implicações que uma atitude pode ou não ter, de acordo com a maneira que escolhemos resolvê-la. O artigo procura destacar como esses temas estão presentes no seriado, e como são determinantes para a evolução das personagens na trama. 

  2. EvoCor: a platform for predicting functionally related genes using phylogenetic and expression profiles.

    Science.gov (United States)

    Dittmar, W James; McIver, Lauren; Michalak, Pawel; Garner, Harold R; Valdez, Gregorio

    2014-07-01

    The wealth of publicly available gene expression and genomic data provides unique opportunities for computational inference to discover groups of genes that function to control specific cellular processes. Such genes are likely to have co-evolved and be expressed in the same tissues and cells. Unfortunately, the expertise and computational resources required to compare tens of genomes and gene expression data sets make this type of analysis difficult for the average end-user. Here, we describe the implementation of a web server that predicts genes involved in affecting specific cellular processes together with a gene of interest. We termed the server 'EvoCor', to denote that it detects functional relationships among genes through evolutionary analysis and gene expression correlation. This web server integrates profiles of sequence divergence derived by a Hidden Markov Model (HMM) and tissue-wide gene expression patterns to determine putative functional linkages between pairs of genes. This server is easy to use and freely available at http://pilot-hmm.vbi.vt.edu/. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  3. Efeito do armazenamento à baixa temperatura (-4 ºC na cor e no teor de acidez da farinha de trigo Effect of storage at low temperature (-4 ºC in the color and acidity content of wheat flour

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    Fernanda Ortolan

    2010-03-01

    Full Text Available Durante o armazenamento de farinha de trigo, podem ocorrer mudanças bioquímicas que resultam em alterações nutricionais e tecnológicas, sendo que em baixa temperatura estas mudanças ocorrem mais lentamente. Entre as alterações, pode-se citar o aumento da acidez, a redução do pH e as modificações na sua cor. O presente trabalho teve por objetivo avaliar os efeitos do armazenamento à baixa temperatura (-4 ºC na cor e na acidez da farinha de trigo durante seis meses e correlacionar os resultados obtidos para investigar se a acidez tem relação com a cor da farinha. Foram utilizadas farinhas provenientes de dez genótipos de trigo cultivados em Cascavel, no Estado do Paraná. A cor foi determinada no sistema CIEL*a*b* através dos parâmetros de cor: L* (luminosidade, a* e b* (coordenadas de cromaticidade. Usou-se procedimento da AOAC para determinação da acidez de lipídios. As farinhas apresentaram tendência ao branqueamento durante o período de seis meses de armazenamento, com ocorrência de leve aumento da acidez, mas dentro dos teores aceitáveis. A acidez não foi considerada um fator envolvido na alteração da cor das farinhas no armazenamento à baixa temperatura, pois não houve correlação entre estes dois parâmetros.During wheat flour storage, biochemical changes can occur which lead to nutritional and technological alterations, but in low temperature these changes can occur more slowly. Among the reactions, we may note are an increase in acidity, reduction of pH and modifications to its color. The present work aimed to evaluate the effects of storage at low temperature (-4 ºC on the color and acidity of wheat flour over six months and to correlate the results obtained to discover whether the acidity has any relationship with the color of the flour. Flours of ten wheat genotypes, cultivated in Cascavel, in Paraná State were used. The color was determined via the CIEL*a*b* system using the color parameters: L

  4. Termoterapia transpupilar como opção terapêutica para hemangioma circunscrito de coróide: relato de caso

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    Roizenblatt Jaime

    2002-01-01

    Full Text Available Os autores descrevem um caso de hemangioma circunscrito de coróide, com descolamento de retina associado, tratado por meio de termoterapia transpupilar com laser de diodo. Os parâmetros utilizados foram: 900 mW, mira de 4,2 mm, tempo de 3 minutos, lente QuadrAspheric (Volkâ com fator de magnificação de 1,97. Um mês após o tratamento ocorreu redução significativa do hemangioma, com recuperação integral da visão deste olho. São feitas considerações a respeito do método, o qual mostra-se promissor no tratamento destes tumores vasculares.

  5. Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9

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    Shuangquan Yan

    2016-01-01

    Full Text Available Baicalin has a protective effect on hypoxia-induced pulmonary hypertension in rats, but the mechanism of this effect remains unclear. Thus, investigating the potential mechanism of this effect was the aim of the present study. Model rats that display hypoxic pulmonary hypertension and cor pulmonale under control conditions were successfully generated. We measured a series of indicators to observe the levels of pulmonary arterial hypertension, pulmonary arteriole remodeling, and right ventricular remodeling. We assessed the activation of p38 mitogen-activated protein kinase (MAPK in the pulmonary arteriole walls and pulmonary tissue homogenates using immunohistochemistry and western blot analyses, respectively. The matrix metalloproteinase- (MMP- 9 protein and mRNA levels in the pulmonary arteriole walls were measured using immunohistochemistry and in situ hybridization. Our results demonstrated that baicalin not only reduced p38 MAPK activation in both the pulmonary arteriole walls and tissue homogenates but also downregulated the protein and mRNA expression levels of MMP-9 in the pulmonary arteriole walls. This downregulation was accompanied by the attenuation of pulmonary hypertension, arteriole remodeling, and right ventricular remodeling. These results suggest that baicalin may attenuate pulmonary hypertension and cor pulmonale, which are induced by chronic hypoxia, by downregulating the p38 MAPK/MMP-9 pathway.

  6. Fusion of Haptic and Gesture Sensors for Rehabilitation of Bimanual Coordination and Dexterous Manipulation.

    Science.gov (United States)

    Yu, Ningbo; Xu, Chang; Li, Huanshuai; Wang, Kui; Wang, Liancheng; Liu, Jingtai

    2016-03-18

    Disabilities after neural injury, such as stroke, bring tremendous burden to patients, families and society. Besides the conventional constrained-induced training with a paretic arm, bilateral rehabilitation training involves both the ipsilateral and contralateral sides of the neural injury, fitting well with the fact that both arms are needed in common activities of daily living (ADLs), and can promote good functional recovery. In this work, the fusion of a gesture sensor and a haptic sensor with force feedback capabilities has enabled a bilateral rehabilitation training therapy. The Leap Motion gesture sensor detects the motion of the healthy hand, and the omega.7 device can detect and assist the paretic hand, according to the designed cooperative task paradigm, as much as needed, with active force feedback to accomplish the manipulation task. A virtual scenario has been built up, and the motion and force data facilitate instantaneous visual and audio feedback, as well as further analysis of the functional capabilities of the patient. This task-oriented bimanual training paradigm recruits the sensory, motor and cognitive aspects of the patient into one loop, encourages the active involvement of the patients into rehabilitation training, strengthens the cooperation of both the healthy and impaired hands, challenges the dexterous manipulation capability of the paretic hand, suits easy of use at home or centralized institutions and, thus, promises effective potentials for rehabilitation training.

  7. Fusion of Haptic and Gesture Sensors for Rehabilitation of Bimanual Coordination and Dexterous Manipulation

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    Ningbo Yu

    2016-03-01

    Full Text Available Disabilities after neural injury, such as stroke, bring tremendous burden to patients, families and society. Besides the conventional constrained-induced training with a paretic arm, bilateral rehabilitation training involves both the ipsilateral and contralateral sides of the neural injury, fitting well with the fact that both arms are needed in common activities of daily living (ADLs, and can promote good functional recovery. In this work, the fusion of a gesture sensor and a haptic sensor with force feedback capabilities has enabled a bilateral rehabilitation training therapy. The Leap Motion gesture sensor detects the motion of the healthy hand, and the omega.7 device can detect and assist the paretic hand, according to the designed cooperative task paradigm, as much as needed, with active force feedback to accomplish the manipulation task. A virtual scenario has been built up, and the motion and force data facilitate instantaneous visual and audio feedback, as well as further analysis of the functional capabilities of the patient. This task-oriented bimanual training paradigm recruits the sensory, motor and cognitive aspects of the patient into one loop, encourages the active involvement of the patients into rehabilitation training, strengthens the cooperation of both the healthy and impaired hands, challenges the dexterous manipulation capability of the paretic hand, suits easy of use at home or centralized institutions and, thus, promises effective potentials for rehabilitation training.

  8. Two-Dimensional Raman Correlation Spectroscopy Study of Poly[(R)-3-hydroxybutyrate- co-(R)-3-hydroxyhexanoate] Copolymers.

    Science.gov (United States)

    Noda, Isao; Roy, Anjan; Carriere, James; Sobieski, Brian J; Chase, D Bruce; Rabolt, John F

    2017-07-01

    Two-dimensional correlation analysis was applied to the time-dependent evolution of Raman spectra during the isothermal crystallization of bioplastic, poly[(R)-3-hydroxybutyrate- co-(R)-3-hydroxyhexanoate] or PHBHx copolymer. Simultaneous Raman measurement of both carbonyl stretching and low-frequency crystalline lattice mode regions made it possible to carry out the highly informative hetero-mode correlation analysis. The crystallization process of PHBHx involves: (1) the early nucleation stage; (2) the primary growth of well-ordered crystals of PHBHx; and (3) the secondary crystal growth phase. The latter stage probably occurs in the inter-lamellar region, with an accompanying reduction of the amorphous component, which occurs most dominantly during the primary crystal growth. The development of a fully formed lamellar structure comprising the 2 1 helices occurs after the primary growth of crystals. In the later stage, secondary inter lamellar space crystallization occurs after the full formation of packed helices comprising the lamellae.

  9. Alteração da cor da madeira de teca por tratamento térmico

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    Juliana de Oliveira Lopes

    Full Text Available O objetivo deste estudo foi determinar o efeito do tratamento térmico na alteração da cor da madeira de teca (Tectona grandis L. f., proveniente de plantios de diferentes espaçamentos. Amostras de madeira de cerne e de alburno foram tratadas a 180 e 200ºC durante 2h30min. As análises colorimétricas foram realizadas com o auxílio do espectrofotômetro CM 2600d no sistema CIE L*a*b*. Após o tratamento, a madeira teve perda de luminosidade, tornado-se mais escura, o que se mostrou mais acentuado para o tratamento a 200ºC. As madeiras de cerne e alburno apresentaram comportamentos diferentes para as coordenadas a* e b*, dependendo do espaçamento, antes e após o tratamento. Ocorreu uma maior formação de pigmento vermelho e perda de pigmento amarelo nas madeiras de cerne e alburno tratadas a 200ºC.

  10. Compliance & dexterity, factors to consider in home care and maintenance procedures Adherencia e destreza: factores a considerar en programas preventivos

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    Victoria Criado

    2007-01-01

    Full Text Available Mechanical plaque control appears to be the primary means of controlling supragingival dental plaque build-up. Although daily oral hygiene practices and periodic professional care are considered the basis for any program aimed at the prevention and treatment of oral diseases, these procedures are technically demanding, time consuming and can be affected by the compliance and manual dexterity of the patient. Individual skills and acquired behavior patterns determine effectiveness of a preventive program and oral hygiene practice. Successful preventive programs and home care procedures clearly depend on the interaction and commitment between the dental professional and the patient. Identifying the capacity of the individual to comply with the professional recommendations and evaluating the dexterity of the patient to remove supragingival dental plaque will permit the implementation of an adequate preventive program and can help on the selection of adjunctive antimicrobial agents and devices needed to reach an effective oral care routine.El control de la placa dental parece ser el mecanismo primario para controlar el crecimiento de la placa dental supragingival. Aunque la práctica diaria de la higiene bucal y el cuidado profesional periódico, son considerados la base para cualquier programa dirigido a la prevención y tratamiento de las enfermedades de la cavidad bucal, estos procedimientos son técnicamente exigentes, consumen tiempo y pueden ser afectados por la aceptación y la destreza manual del paciente. Las destrezas individuales y los patrones de comportamiento adquiridos, determinan la efectividad de un programa preventivo y la práctica de la higiene bucal. El éxito de los programas preventivos y los procedimientos del cuidado bucal en el hogar dependen claramente de la interacción y compromiso entre el odontólogo y el paciente. La importancia de identificar la capacidad del individuo para cumplir con las recomendaciones y la

  11. Calculating length of gestation from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) database versus vital records may alter reported rates of prematurity.

    Science.gov (United States)

    Stern, Judy E; Kotelchuck, Milton; Luke, Barbara; Declercq, Eugene; Cabral, Howard; Diop, Hafsatou

    2014-05-01

    To compare length of gestation after assisted reproductive technology (ART) as calculated by three methods from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) and vital records (birth and fetal death) in the Massachusetts Pregnancy to Early Life Longitudinal Data System (PELL). Historical cohort study. Database linkage analysis. Live or stillborn deliveries. None. ART deliveries were linked to live birth or fetal death certificates. Length of gestation in 7,171 deliveries from fresh autologous ART cycles (2004-2008) was calculated and compared with that of SART CORS with the use of methods: M1 = outcome date - cycle start date; M2 = outcome date - transfer date + 17 days; and M3 = outcome date - transfer date + 14 days + day of transfer. Generalized estimating equation models were used to compare methods. Singleton and multiple deliveries were included. Overall prematurity (delivery 45% of deliveries and by more than 1 week in >22% of deliveries. Each method differed from each other. Estimates of preterm birth in ART vary depending on source of data and method of calculation. Some estimates may overestimate preterm birth rates for ART conceptions. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  12. El gesto coréutico en la música hispánica de la segunda mitad del siglo XVIII: una propuesta de interpretación históricamente informada del fandango

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    María José Ruiz Mayordomo

    2015-01-01

    Full Text Available Dentro del marco que ofrece este congreso dedicado al fandango, el equipo formado por la coreóloga María José Ruiz Mayordomo y la musicóloga Aurèlia Pessarrodona quiere presentar un estudio de este género desde su gesto, un aspecto prácticamente ausente dentro de los múltiples enfoques de los que ha sido objeto. Nuestra propuesta parte de una metodología transdisciplinar (músicocoréutica y teóricopráctica que analiza la gestualidad de la obra musical misma captada a través del cuerpo danzante ideal de la segunda mitad del siglo XVIII, estableciendo a su vez un diálogo con el entorno coréutico de la época. Nuestro objetivo en este trabajo es restaurar un fandango de teatro del siglo XVIII. Ante la escasez de testimonios escritos, tomamos como fuentes principales fandangos coréuticos antiguos conservados en la tradición bolera, transmitida de manera ágrafa, oral, visual, corporal y artística, es decir, por aprendizaje directo entre transmisor repetidor y maestro e intérprete. En este caso partimos del baile conocido como Fandango del Siglo XVIII, cuya coreografía encaja perfectamente con la música de un fandango de teatro de finales de siglo XVIII compuesto por Bernardo Álvarez Acero. El análisis de la relación entre gestos musicales y coréuticos de ambas obras proporciona claves para entender estos y otros fandangos musicales de la época. Así pues, esta propuesta pretende acercar a teóricos e intérpretes al fenómeno del fandango de un modo más integral, de cara a restaurar e interpretar estas obras desde un punto de vista coreográfica y coreológicamente informado.

  13. Mortalidade por raça/cor: evidências de desigualdades sociais em Vitória (ES, Brasil Mortality by race/color: evidence of social inequalities in Vitória (ES, Brazil

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    Nathalia Modenesi Fiorio

    2011-09-01

    Full Text Available OBJETIVO: Analisar a mortalidade por causa básica, sexo e raça/cor a partir do sistema de informações sobre mortalidade (SIM, em Vitória (ES, no período de 2003 a 2006. MÉTODOS: Foram calculados e analisados os coeficientes de mortalidade, segundo causa básica e sexo por raça/cor, bem como a idade média e mediana de óbito por causa básica, sexo e raça/cor. Foi calculado o risco relativo (RR por sexo, idade e causa básica (pOBJECTIVE: To analyze mortality by cause and sex among groups of race or color from the mortality information system (MIS in Vitória (Brazil, in the period from 2003 to 2006. METHODS: We calculated and analyzed the mortality rates according to underlying cause, sex and race/color, and the mean and median age of death by underlying cause, sex and race. We calculated the relative risk (RR for age, sex and underlying cause (p<0.05 and CI 95%. RESULTS: The completeness of race/color in SIM ranged from 1% in 1996 to 81% in 2006. There was a greater RR of death among blacks for mental and behavioral disorders (RR=9.29, Ill-defined causes (RR=8.71, and external causes (RR=5.71. For black women, we highlight the external causes (RR=2.38. We found a variation of up to 33 years (nervous system between whites and blacks. CONCLUSION: This study confirms the existence of unequal racial/ethnic mortality, highlighting the mortality from mental disorders and external causes, in addition to early mortality that occurs in the black population.

  14. Espectro óculo-aurículo-vertebral e malformações cardíacas Oculo-auriculo-vertebral spectrum and cardiac malformations

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    Rafael Fabiano Machado Rosa

    2010-01-01

    Full Text Available OBJETIVO: Verificar a frequência e tipos de cardiopatias congênitas em uma amostra de pacientes portadores de espectro óculo-aurículo-vertebral (EOAV, tentando correlacionar a presença desta malformação com suas demais características clínicas e evolução. MÉTODOS: A amostra foi composta por 33 indivíduos, todos atendidos em um mesmo centro, no período de janeiro de 1975 a dezembro de 2007. Vinte e dois deles eram do sexo masculino e 11 do feminino e suas idades variaram de 1 dia a 17 anos. Todos apresentavam avaliação cariotípica normal por bandas GTG. Realizou-se uma coleta de dados referentes à sua história clínica, exame físico e resultado de avaliações complementares. RESULTADOS: Anormalidades cardíacas foram observadas em 13 pacientes (39,4%. Dessas, cinco (38,5% eram do tipo conotruncal, sendo o principal defeito a tetralogia de Fallot (n=2. Malformações não usuais identificadas incluíram o cor triatriatum e a dupla via de entrada de ventrículo esquerdo. Diferenças significativas entre as características clínicas do grupo com e sem cardiopatia foram verificadas somente em relação à idade na primeira avaliação, que foi mais baixa naqueles com malformações cardíacas. Cinco indivíduos foram a óbito, quatro deles portadores desses defeitos. CONCLUSÃO: Malformações cardíacas, em especial dos tipos conotruncal e septal, são frequentes entre pacientes com EOAV. A frequência encontrada em nosso estudo foi estatisticamente similar à da maior parte dos trabalhos descritos na literatura, que oscila de 18% a 58%. As cardiopatias congênitas também representam a principal causa de óbito desses indivíduos. Portanto, uma avaliação cardiológica, especialmente precoce, deveria ser sempre realizada nesses pacientes.OBJECTIVE: To verify the frequency and types of congenital heart defects in a sample of patients with oculo-auriculo-vertebral spectrum (OAVS, in an effort to correlate presence of these

  15. Dimensionamento amostral para avaliar firmeza de polpa e cor da epiderme em pêssego e maçã Sample size to evaluate the flesh firmness and epidermis color in peach and apple

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    Marcos Toebe

    2011-12-01

    Full Text Available O objetivo deste estudo foi determinar o tamanho de amostra necessário para avaliar a firmeza de polpa e a cor de fundo da epiderme, em pêssego 'Eragil' e maçã 'Royal Gala'. Foram conduzidos dois experimentos, um com frutos de pêssego e outro com frutos de maçã dentro de minicâmaras de 0,23 m³. Os pêssegos foram armazenados por oito semanas a temperatura de -0,5 ºC, mais quatro dias a 20 ºC, sendo avaliadas oito formas de armazenamento (refrigerado, atmosfera controlada com diferentes concentrações de O2 e CO2, e com ou sem absorção de etileno. As maçãs permaneceram em armazenamento refrigerado durante quatro meses a 0,5 ºC, mais sete dias a 20 ºC, sendo os tratamentos compostos por doses de 1-metilciclopropeno combinados com tipos de tábuas de madeira. O número de frutos avaliados variou de 30 a 57 em pêssego e 78 a 101 em maçã. Para cada fruto foi mensurada a firmeza de polpa, com um penetrômetro manual e a cor de fundo da epiderme (luminosidade, intensidade e tonalidade de cor com colorímetro eletrônico. Posteriormente, foi determinado o tamanho de amostra necessário para a estimação da média da firmeza de polpa e da cor de fundo da epiderme. Em pêssego, 121 frutos são suficientes para a estimação da média da firmeza de polpa e da cor de fundo da epiderme com erro de estimação de 5% da média em atmosfera controlada e de 10% em armazenamento refrigerado. Em maçã, 24 frutos são suficientes para a estimação da média da firmeza de polpa e da cor de fundo da epiderme, com erro de estimação de 5% da média.The aim of this study was to determine the sample size required to asses flesh firmness and epidermis background color of 'Eragil' peaches and 'Royal Gala' apples. Two experiments were carried, one with peaches and another one with apples placed inside 0.23 m³ minichambers. The peaches were stored for eight weeks at -0.5 ºC, and then for four additional days at 20 °C, next eight kinds of storage

  16. Analisa Kekuatan Sambungan Pipa Baja Karbon dan Besi Cor Berbasis Teknologi Las Gesek (Friction Welding

    Directory of Open Access Journals (Sweden)

    Nur Husodo

    2016-12-01

    Full Text Available Abstrak: Adanya kesulitan yang akan terjadi manakala dilakukan proses penyambungan dua buah logam yang berbedakomposisi. Namun ada alternative metode proses penyambungan logam baja yang berbeda komposisi dengan metodelas gesek. Selain itu metode las gesek ini mempunyai banyak keunggulan antara lain waktu proses cepat, tidak perlulogam pengisi, panas yang terjadi tidak sampai logam mencair, panas yang terjadi tidak terlalu tinggi juga mudahditerapkan karena dapat memanfaatkan mesin perkakas. Oleh karena itu perlu dilakukan proses penyambungan denganmetode las gesek untuk alternative proses pembuatan produk stang sepeda motor. Penelitian dilakukan denganmemvariasi tekanan tempa sebesar 375, 437,5 dan 500 kgf/cm2 , tekanan gesek 62,5 kgf/cm2 dan durasi waktu gesek120 detik. Sampel uji yang dihasilkan dilakukan pengujian struktur mikro dengan metallografi sedangkan sifat mekanikdilakukan dengan pengujian kekerasan dan kekuatan tarik. Analisa dilakukan untuk mengetahui peluang las gesekdipakai sebagai alternative proses produksi produk stang sepeda motor. Dapat ditarik kesimpulan bahwa metode lasgesek dapat digunakan menyambung dua buah logam baja yang berbeda kompisi yaitu pipa baja karbon rendah denganbesi cor. Kekuatan las akan meningkat ketika tekanan tempa juga meningkat. Kekuatan sambungan tertinggi sebesar546,66 N/mm2.Kata kunci: Las gesek, pipa baja karbon rendah, besi cor, tekanan tempa, tekanan gesek Abstract: The difficulties that will occur when the process of joining two pieces made of different metal compositions. However,there are alternative methods of process connection of different steel metal composition with friction welding method.Besides this friction welding method has many advantages such as faster processing time, do not need filler metal, theheat does not occur until the metal melts, heat is happening is not too high is also easy to implement because it can takeadvantage of machine tools. Therefore, it is necessary to the

  17. Status of NGS CORS Network and Its Contribution to the GGOS Infrastructure

    Science.gov (United States)

    Choi, K. K.; Haw, D.; Sun, L.

    2017-12-01

    Recent advancement of Satellite Geodesy techniques can now contribute to the global frame realization needed to improve worldwide accuracies. These techniques rely on coordinates computed using continuously observed GPS data and corresponding satellite orbits. The GPS-based reference system continues to depend on the physical stability of a ground-based network of points as the primary foundation for these observations. NOAA's National Geodetic Survey (NGS) has been operating Continuously Operating Reference Stations (CORS) to provide direct access to the National Spatial Reference System (NSRS). By virtue of NGS' scientific reputation and leadership in national and international geospatial issues, NGS has determined to increase its participation in the maintenance of the U.S. component of the global GPS tracking network in order to realize a long-term stable national terrestrial reference frame. NGS can do so by leveraging its national leadership role coupled with NGS' scientific expertise, in designating and upgrading a subset of the current tracking network for this purpose. This subset of stations must have the highest operational standards to serve the dual functions: being the U.S. contribution to the international frame, along with providing the link to the national datum. These stations deserve special attention to ensure that the highest possible levels of quality and stability are maintained. To meet this need, NGS is working with the international scientific groups to add and designate these reference stations based on scientific merit such as: colocation with other geodetic techniques, geographic area, and monumentation stability.

  18. CorRECTreatment: a web-based decision support tool for rectal cancer treatment that uses the analytic hierarchy process and decision tree.

    Science.gov (United States)

    Suner, A; Karakülah, G; Dicle, O; Sökmen, S; Çelikoğlu, C C

    2015-01-01

    The selection of appropriate rectal cancer treatment is a complex multi-criteria decision making process, in which clinical decision support systems might be used to assist and enrich physicians' decision making. The objective of the study was to develop a web-based clinical decision support tool for physicians in the selection of potentially beneficial treatment options for patients with rectal cancer. The updated decision model contained 8 and 10 criteria in the first and second steps respectively. The decision support model, developed in our previous study by combining the Analytic Hierarchy Process (AHP) method which determines the priority of criteria and decision tree that formed using these priorities, was updated and applied to 388 patients data collected retrospectively. Later, a web-based decision support tool named corRECTreatment was developed. The compatibility of the treatment recommendations by the expert opinion and the decision support tool was examined for its consistency. Two surgeons were requested to recommend a treatment and an overall survival value for the treatment among 20 different cases that we selected and turned into a scenario among the most common and rare treatment options in the patient data set. In the AHP analyses of the criteria, it was found that the matrices, generated for both decision steps, were consistent (consistency ratiodecisions of experts, the consistency value for the most frequent cases was found to be 80% for the first decision step and 100% for the second decision step. Similarly, for rare cases consistency was 50% for the first decision step and 80% for the second decision step. The decision model and corRECTreatment, developed by applying these on real patient data, are expected to provide potential users with decision support in rectal cancer treatment processes and facilitate them in making projections about treatment options.

  19. Em busca dos rastros perdidos da memória ancestral: um estudo de Um defeito de cor, de Ana Maria Gonçalves

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    Zilá Bernd

    2012-01-01

    Full Text Available The article provides a theoretical reflection upon the concept of traces, evoking the main authors who have defined it, such as P. Ricoeur, C. Ginzburg, J.-M. Gagnebin, E. Glissant and S. J. Pesavento, among others, and introducing termi- nological variants such as vestiges, ruins, residues, marks etc. We consider the importance of this concept in order to rethink the memory work in contemporary literary texts, especially in Ana Maria Gonçalves' novel Um defeito de cor (Record, 2010, which is an outstanding example of the recovery of African-Brazilian col- lective memory from traces.

  20. Anticipatory planning and control of grasp positions and forces for dexterous two-digit manipulation.

    Science.gov (United States)

    Fu, Qiushi; Zhang, Wei; Santello, Marco

    2010-07-07

    Dexterous object manipulation requires anticipatory control of digit positions and forces. Despite extensive studies on sensorimotor learning of digit forces, how humans learn to coordinate digit positions and forces has never been addressed. Furthermore, the functional role of anticipatory modulation of digit placement to object properties remains to be investigated. We addressed these questions by asking human subjects (12 females, 12 males) to grasp and lift an inverted T-shaped object using precision grip at constrained or self-chosen locations. The task requirement was to minimize object roll during lift. When digit position was not constrained, subjects could have implemented many equally valid digit position-force coordination patterns. However, choice of digit placement might also have resulted in large trial-to-trial variability of digit position, hence challenging the extent to which the CNS could have relied on sensorimotor memories for anticipatory control of digit forces. We hypothesized that subjects would modulate digit placement for optimal force distribution and digit forces as a function of variable digit positions. All subjects learned to minimize object roll within the first three trials, and the unconstrained device was associated with significantly smaller grip forces but larger variability of digit positions. Importantly, however, digit load force modulation compensated for position variability, thus ensuring consistent object roll minimization on each trial. This indicates that subjects learned object manipulation by integrating sensorimotor memories with sensory feedback about digit positions. These results are discussed in the context of motor equivalence and sensorimotor integration of grasp kinematics and kinetics.

  1. Diagnosis of secondary pulmonary lymphangiectasia in congenital heart disease: a novel role for chest ultrasound and prognostic implications.

    Science.gov (United States)

    Lam, Christopher Z; Bhamare, Tanmay Anant; Gazzaz, Tamadhir; Manson, David; Humpl, Tilman; Seed, Mike

    2017-10-01

    Secondary pulmonary lymphangiectasia is a complication of congenital heart disease that results from chronic pulmonary venous obstruction. We aimed to evaluate the performance of chest ultrasound (US) in diagnosing secondary pulmonary lymphangiectasia and to review the clinical course of children with secondary pulmonary lymphangiectasia. Chest US was performed on 26 children with hypoplastic left heart syndrome, total anomalous pulmonary venous connection or cor triatriatum in a prospective observational study. Thirteen children had pulmonary venous obstruction (62% male; median age: 17 days old, range: 1-430 days old) and 13 children did not have obstruction (62% male; median age: 72 days old, range: 4-333 days old). US features of secondary pulmonary lymphangiectasia were documented and diagnostic performance was determined. Clinical course of patients with secondary pulmonary lymphangiectasia was reviewed. Eleven of 13 (84.6%) patients in the obstructed group had a clinical and/or biopsy diagnosis of secondary pulmonary lymphangiectasia. Statistically significant chest US criteria for diagnosis were presence of irregular lung surface (likelihood ratio [LR] 6.8, 95% confidence interval [CI] 1.9-25.1), subpleural cystic appearing structures (LR 3.6, 95% CI 1.2-10.7), and combination of subpleural cystic appearing structures and surface irregularity together (LR 10.9, 95% CI 1.6-75.0). Seven of 11 (63.6%) patients with secondary pulmonary lymphangiectasia died during follow-up, the majority due to cardiopulmonary failure or complications. Chest US is an accurate and reproducible bedside method for diagnosing secondary pulmonary lymphangiectasia in patients with pulmonary venous obstruction. These patients may have worse prognoses.

  2. Protective gloves for use in high-risk patients: how much do they affect the dexterity of the surgeon?

    Science.gov (United States)

    Phillips, A. M.; Birch, N. C.; Ribbans, W. J.

    1997-01-01

    Twenty-five orthopaedic surgeons underwent eight motor and sensory tests while using four different glove combinations and without gloves. As well as single and double latex, surgeons wore a simple Kevlar glove with latex inside and outside and then wore a Kevlar and Medak glove with latex inside and outside, as recommended by the manufacturers. The effect of learning with each sequence was neutralised by randomising the glove order. The time taken to complete each test was recorded and, where appropriate, error rates were noted. Simple sensory tests took progressively longer to perform so that using the thickest glove combination led to the completion times being doubled. Error rates increased significantly. Tests of stereognosis also took longer and use of the thickest glove combination caused these tests to take three times as long on average. Error rates again increased significantly. However, prolongation of motor tasks was less marked. We conclude that, armed with this quantitative analysis of sensitivity and dexterity impairment, surgeons can judge the relative difficulties that may be incurred as a result of wearing the gloves against the benefits that they offer in protection. PMID:9135240

  3. L'exemple d'un décor religieux dans le nord de la France : Bruno Chérier (1817-1880 et Notre-Dame-des-Anges de Tourcoing

    Directory of Open Access Journals (Sweden)

    Catherine Guillot

    2012-04-01

    Full Text Available Ami et modèle du sculpteur Jean-Baptiste Carpeaux, Bruno Chérier (1817 Valenciennes, 1880 Paris se consacre à partir de la fin des années 1850 jusqu'à sa mort au décor religieux dans le nord de la France. Devenu en 1852 professeur aux écoles académiques de Tourcoing, il répond aux commandes les plus variées dans le domaine de l'art religieux. Ainsi, sa participation au décor de l'église Notre-Dame-des-Anges de Tourcoing est exemplaire de la diversité de ses contributions : chemin de croix, cartons de vitraux, peintures ornementales illusionnistes. Cette église constitue en outre dans le Nord un des rares témoignages conservé presque intégralement de l'art religieux dans la seconde moitié du XIXe siècle. La collaboration de Chérier à ce chantier témoigne d'un statut de l'artiste sous le Second Empire, éloigné de l'image romantique du créateur libre dont est redevable le mythe constitué autour de la figure de Carpeaux.Les auteurs préparent une étude globale de l'œuvre de Bruno Chérier et de son rôle auprès de Carpeaux.

  4. COR1 Engineering Test Unit Measurements at the Mauna Loa Solar Observatory, September 2003

    Science.gov (United States)

    Thompson, William; Reginald, Nelson; Streander, Kim

    2003-01-01

    The COR1 Engineering Test Unit (ETU), which had been previously tested at the NCAR/HAO and NRL test facilities, was modified into an instrument capable of observing the Sun. It was then taken to the Mauna Loa Solar Observatory to observe the corona. The changes made to observe the Sun were as follows: 1. The plate scale was changed to accommodate the smaller Apogee camera. This change had already been made for the NRL tests. 2. The previous Oriel polarizer was replaced with a commercial Polarcor polarizer from Newport to be more flight-like. However, because of cost and availability considerations, this polarizer was smaller than those which will be used for flight. 3. A structure was placed around the back section of the instrument, to protect it from stray light. 4. A pointing spar borrowed from HAO was used to track the Sun. A few days into the test, it became evident that some artifacts were appearing in the data, and these artifacts were changing as the polarizer was rotated. It was decided to test two other polarizers, the Oriel polarizer which had been used in the previous tests at HAO and NRL, and a Nikon polarizer which was borrowed from a camera belonging to one of the observatory staff members. These three polarizers had much different qualities are shown.

  5. Arterial stiffness estimation in healthy subjects: a validation of oscillometric (Arteriograph) and tonometric (SphygmoCor) techniques.

    Science.gov (United States)

    Ring, Margareta; Eriksson, Maria Jolanta; Zierath, Juleen Rae; Caidahl, Kenneth

    2014-11-01

    Arterial stiffness is an important cardiovascular risk marker, which can be measured noninvasively with different techniques. To validate such techniques in healthy subjects, we compared the recently introduced oscillometric Arteriograph (AG) technique with the tonometric SphygmoCor (SC) method and their associations with carotid ultrasound measures and traditional risk indicators. Sixty-three healthy subjects aged 20-69 (mean 48 ± 15) years were included. We measured aortic pulse wave velocity (PWVao) and augmentation index (AIx) by AG and SC, and with SC also the PWVao standardized to 80% of the direct distance between carotid and femoral sites (St-PWVaoSC). The carotid strain, stiffness index and intima-media thickness (cIMTmean) were evaluated by ultrasound. PWVaoAG (8.00 ± 2.16 m s(-1)) was higher (Pstiffness indices by AG and SC correlate with vascular risk markers in healthy subjects. AIxao results by AG and SC are closely interrelated, but higher values are obtained by AG. In the lower range, PWVao values by AG and SC are similar, but differ for higher values. Our results imply the necessity to apply one and the same technique for repeated studies.

  6. Use of Bacillus pumilus CBMAI 0008 and Paenibacillus sp. CBMAI 868 for colour removal from paper mill effluent Emprego de Bacillus pumilus CBMAI 0008 e Paenibacillus sp. CBMAI 868 para remoção da cor do efluente da indústria papeleira

    Directory of Open Access Journals (Sweden)

    Patrícia Lopes de Oliveira

    2009-06-01

    Full Text Available Bacillus pumilus and Paenibacillus sp. were applied on the paper mill effluent to investigate the colour remotion. Inocula were individually applied in effluent at pH 7.0, 9.0 and 11.0. The real colour and COD remotion after 48h at pH 9.0 were, respectively, 41.87% and 22.08% for B. pumilus treatment and 42.30% and 22.89% for Paenibacillus sp. Gel permeation chromatography was used to verify the molar masses of compounds in the non-treated and treated effluent, showing a decrease in the compounds responsible for the paper mill effluent colour.Bacillus pumilus e Paenibacillus sp. foram aplicados separadamente no efluente da indústria papeleira a pH 7,0, 9,0 e 11,0, para verificação da remoção da cor e da DQO. As remoções da cor real e DQO após 48h a pH 9,0 foram, respectivamente, de 41,87% e 22,08% após o tratamento com B. pumilus e 42,30% e 22,89% após tratamento com Paenibacillus sp. As massas molares dos compostos presentes no efluente não tratado e tratado foram determinadas por cromatografia de permeação em gel. O emprego dos microrganismos reduziu os compostos responsáveis pela cor do efluente da indústria papeleira.

  7. Study of Sequential Dexter Energy Transfer in High Efficient Phosphorescent White Organic Light-Emitting Diodes with Single Emissive Layer

    Science.gov (United States)

    Kim, Jin Wook; You, Seung Il; Kim, Nam Ho; Yoon, Ju-An; Cheah, Kok Wai; Zhu, Fu Rong; Kim, Woo Young

    2014-11-01

    In this study, we report our effort to realize high performance single emissive layer three color white phosphorescent organic light emitting diodes (PHOLEDs) through sequential Dexter energy transfer of blue, green and red dopants. The PHOLEDs had a structure of; ITO(1500 Å)/NPB(700 Å)/mCP:Firpic-x%:Ir(ppy)3-0.5%:Ir(piq)3-y%(300 Å)/TPBi(300 Å)/Liq(20 Å)/Al(1200 Å). The dopant concentrations of FIrpic, Ir(ppy)3 and Ir(piq)3 were adjusted and optimized to facilitate the preferred energy transfer processes attaining both the best luminous efficiency and CIE color coordinates. The presence of a deep trapping center for charge carriers in the emissive layer was confirmed by the observed red shift in electroluminescent spectra. White PHOLEDs, with phosphorescent dopant concentrations of FIrpic-8.0%:Ir(ppy)3-0.5%:Ir(piq)3-0.5% in the mCP host of the single emissive layer, had a maximum luminescence of 37,810 cd/m2 at 11 V and a luminous efficiency of 48.10 cd/A at 5 V with CIE color coordinates of (0.35, 0.41).

  8. Estudo comparativo da flarefotometria em pacientes com melanoma maligno e nevo de coróide Comparative study of flare photometry in patients with choroidal malignant melanoma and choroidal nevus

    Directory of Open Access Journals (Sweden)

    Priscilla Luppi Ballalai

    2002-01-01

    Full Text Available Introdução: Os tumores malignos intra-oculares estão associados com um aumento do "flare" na câmara anterior, causado por uma quebra na barreira hemato-aquosa, que pode ocorrer por vários mecanismos. Estudos utilizando a flarefotometria confirmam o aumento do "flare" em olhos com tumores intra-oculares malignos e benignos. Objetivo: Avaliar a flarefotometria como auxiliar no diagnóstico diferencial de melanoma maligno e nevo de coróide, comparando-se com olhos contralaterais normais. Métodos: Foram avaliados olhos com melanoma maligno e olhos com nevo de coróide diagnosticados por meio de oftalmoscopia indireta e/ou ultra-sonografia. Os olhos normais contralaterais foram utilizados como controles. A flarefotometria foi realizada em todos os pacientes, sob midríase bilateral, utilizando equipamento Laser Flare Meter (FC 500, Kowa. Foram aplicados os testes de Wilcoxon, Mann-Whitney, e Spearman para análise estatística. Resultados: A média da flarefotometria nos olhos com melanoma maligno de coróide foi 17,1 ph/ms e nos olhos normais contralaterais foi 4,06 ph/ms. Nos olhos com nevo de coróide o valor da flarefotometria foi 6,12 ph/ms e nos olhos contralaterais normais foi 4,47 ph/ms. O valor da flarefotometria foi maior nos olhos com melanoma maligno e nevo quando comparado com os olhos contralaterais normais (pIntroduction: Malignant intraocular tumors are associated with an increase in the aqueous flare, caused by alterations of the blood-ocular barriers through various mechanisms. Several studies have demonstrated an ocular flare increase using flare photometry in eyes with benign and malignant tumors. Purpose: To evaluate flare photometry as an adjunct method in the differential diagnosis of choroidal malignant melanoma and choroidal nevus comparing to normal control eyes. Methods: Eyes with melanoma and nevus were diagnosed by indirect binocular ophthalmoscopy and/or ultrasound were evaluated. The fellow normal eyes were used

  9. Relationship between grain colour and preharvest sprouting-resistance in wheat Relação entre cor de grão e resistência à germinação pré-colheita em trigo

    Directory of Open Access Journals (Sweden)

    Manoel Carlos Bassoi

    2005-10-01

    Full Text Available Since red alleles (R of the genes that control grain colour are important for the improvement of preharvest sprouting resistance in wheat and there are three independently inherited loci, on chromosomes 3A, 3B and 3D of hexaploid wheat, it is possible to vary the dosage of dominant alleles in a breeding program. The objective of this work was to evaluate the dosage effect of R genes on preharvest sprouting, in a single seed descent population, named TRL, derived from the cross between Timgalen, white-grained wheat, and RL 4137, red-grained wheat. The study was carried out using sprouting data in ripe ears obtained under artificial conditions in a rainfall simulator over three years. According to the results there is a significant effect on preharvest sprouting provided by colour and a weaker effect of increasing R dosage. However, the significant residual genotypic variation between red lines and all lines (reds and whites at 0.1% level showed that preharvest sprouting was also controlled by other genes. There are no significant correlations between sprouting and date of ripeness or between ripeness, R dosage and colour intensity.Uma vez que os alelos dominantes para cor vermelha (R, dos genes que controlam a cor do grão, têm importância no incremento da resistência à germinação pré-colheita, em trigo, e há três locos herdados independentemente, nos cromossomos 3A, 3B e 3D do trigo hexaplóide, é possível variar sua dosagem em um programa de melhoramento. O objetivo deste trabalho foi avaliar o efeito de dosagem dos genes R na germinação pré-colheita, em uma população de descendência por semente única, batizada de TRL, derivada do cruzamento entre Timgalen, trigo de grão branco, e RL 4137, trigo de grão vermelho. O estudo utilizou dados de germinação em espigas maduras, obtidos sob condições artificiais em um simulador de chuva, em três anos. De acordo com os resultados, o efeito da cor de grão e, menos acentuadamente

  10. Choroid plexus carcinoma in a cow Carcinoma de plexo coróide em um bovino

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    Fabiano José Ferreira de Sant'Ana

    2009-10-01

    Full Text Available A red, firm 3.5x3.0x3.0cm mass was found within the right lateral ventricle, compressing the hippocampus and thalamus of the brain of a 4-year-old cow. The pituitary was enlarged and firm. Histologically, both the brain and pituitary masses consisted of moderately pleomorphic epithelial cells arranged as rosettes or sheets supported by a delicate fibrovascular stroma. Based on anatomical localization, histopathological and immunohistochemical findings, a diagnosis of choroid plexus carcinoma with pituitary metastasis was made.Um massa vermelha e firme de 3,5x3,0x3,0cm foi observada no ventrículo lateral, comprimindo o hipocampo e tálamo do cérebro de uma vaca de quatro anos de idade. A pituitária estava aumentada de volume e firme. Histologicamente, tanto a massa do cérebro, quanto da pituitária, consistiam de células epiteliais moderadamente pleomórficas, arranjadas em rosetas ou cordões e apoiadas em um delicado estroma fibrovascular. Com base na localização anatômica e nos achados histopatológicos e imuno-histoquímicos, foi realizado um diagnóstico de carcinoma de plexo coróide com metástase para a pituitária.

  11. Contralaterally Controlled Functional Electrical Stimulation Improves Hand Dexterity in Chronic Hemiparesis: A Randomized Trial.

    Science.gov (United States)

    Knutson, Jayme S; Gunzler, Douglas D; Wilson, Richard D; Chae, John

    2016-10-01

    It is unknown whether one method of neuromuscular electrical stimulation for poststroke upper limb rehabilitation is more effective than another. Our aim was to compare the effects of contralaterally controlled functional electrical stimulation (CCFES) with cyclic neuromuscular electrical stimulation (cNMES). Stroke patients with chronic (>6 months) moderate to severe upper extremity hemiparesis (n=80) were randomized to receive 10 sessions/wk of CCFES- or cNMES-assisted hand opening exercise at home plus 20 sessions of functional task practice in the laboratory for 12 weeks. The task practice for the CCFES group was stimulation assisted. The primary outcome was change in Box and Block Test (BBT) score at 6 months post treatment. Upper extremity Fugl-Meyer and Arm Motor Abilities Test were also measured. At 6 months post treatment, the CCFES group had greater improvement on the BBT, 4.6 (95% confidence interval [CI], 2.2-7.0), than the cNMES group, 1.8 (95% CI, 0.6-3.0), between-group difference of 2.8 (95% CI, 0.1-5.5), P=0.045. No significant between-group difference was found for the upper extremity Fugl-Meyer (P=0.888) or Arm Motor Abilities Test (P=0.096). Participants who had the largest improvements on BBT were <2 years post stroke with moderate (ie, not severe) hand impairment at baseline. Among these, the 6-month post-treatment BBT gains of the CCFES group, 9.6 (95% CI, 5.6-13.6), were greater than those of the cNMES group, 4.1 (95% CI, 1.7-6.5), between-group difference of 5.5 (95% CI, 0.8-10.2), P=0.023. CCFES improved hand dexterity more than cNMES in chronic stroke survivors. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00891319. © 2016 American Heart Association, Inc.

  12. The maize CorA/MRS2/MGT-type Mg transporter, ZmMGT10, responses to magnesium deficiency and confers low magnesium tolerance in transgenic Arabidopsis.

    Science.gov (United States)

    Li, Hongyou; Wang, Ning; Ding, Jianzhou; Liu, Chan; Du, Hanmei; Huang, Kaifeng; Cao, Moju; Lu, Yanli; Gao, Shibin; Zhang, Suzhi

    2017-10-01

    ZmMGT10 was specifically expressed in maize roots and induced by a deficiency of magnesium. Overexpression of ZmMGT10 restored growth deficiency of the Salmonella typhimurium MM281 strain and enhanced the tolerance in Arabidopsis to stress induced by low magnesium levels by increasing uptake of Mg 2+ via roots. CorA/MRS2/MGT-type Mg 2+ transporters play a significant role in maintaining magnesium (Mg) homeostasis in plants. Although the maize CorA/MRS2/MGT family comprises of 12 members, currently no member has been functionally characterized. Here, we report the isolation and functional characterization of ZmMGT10 from the maize MRS2/MGT gene family. ZmMGT10 has a typical structure feature which includes two conserved TMs near the C-terminal end and an altered AMN tripeptide motif. The high sequence similarity and close phylogenetic relationship indicates that ZmMGT10 is probably the counterpart of Arabidopsis AtMGT6. The complementation of the Salmonella typhimurium mutated MM281 strain indicates that ZmMGT10 possesses the ability to transport Mg 2+ . ZmMGT10 was specifically expressed in the plant roots and it can be stimulated by a deficiency of Mg. Transgenic Arabidopsis plants which overexpressed ZmMGT10 grew more vigorously than wild-type plants under low Mg conditions, exhibited by longer root length, higher plant fresh weight and chlorophyll content, suggesting ZmMGT10 was essential for plant growth and development under low Mg conditions. Further investigations found that high accumulation of Mg 2+ occurred in transgenic plants attributed to improved Mg 2+ uptake and thereby enhanced tolerance to Mg deficiency. Results from this investigation illustrate that ZmMGT10 is a Mg transporter of maize which can enhance the tolerance to Mg deficient conditions by improving Mg 2+ uptake in the transgenic plants of Arabidopsis.

  13. "Cor Occidere": a novel strategy of targeting the tumor core by radiosurgery in a radio- and chemo-resistant intracranial hemangiopericytoma.

    Science.gov (United States)

    Li, You Quan; Chua, Eu Tiong; Chua, Kevin L M; Chua, Melvin L K

    2018-02-01

    Intracranial hemangiopericytomas (HPC) are chemotherapy- and radiotherapy (RT)-resistant. Here, we report on a novel stereotactic radiosurgery (SRS) technique-"Cor Occidere" (Latin), as a potential strategy of overcoming radioresistance of HPC. A 36-year old female presented to our clinic for consideration of a 3rd-course of RT for her recurrent cavernous sinus HPC, following previous cranial RT at 13 and 5 years prior, and a failed 9 months trial of bevacizumab/temozolomide. The tumor-adjacent brain stem and carotid artery risked substantial damage given the cumulative RT doses to these organs. We therefore designed an SRS plan targeting only the tumor core with 16 Gy single-fraction. Despite underdosing the tumor margin, we achieved stable disease over 25 months, contrasting her responses to systemic therapies. Achieving tumor control despite a suboptimal treatment that utilized high dose ablation of the tumor core suggests novel biological mechanisms to overcome radioresistance of HPC.

  14. Esquistossomose pulmonar. II. Forma crônica reativada com hipertensão e Cor pulmonale

    Directory of Open Access Journals (Sweden)

    Jayme Neves

    1980-12-01

    Full Text Available Os Autores descrevem um caso grave de esquistossomose mansoni (forma hepática com hipertensão portal associada a forma pulmonar com hipertensão pulmonar e cor pulmonalej sobre o qual evoluiu uma sindrome toxi-infectuosa grave e de longa duração. Sucessivos exames radiológicos do tórax revelaram acometimento predominantemente arteriolar, ao lado de uma micronodulação pulmonar grosseira e difusa em ambos os hemitóraces e configuração de coração pulmonar. A histopatologia de material de biópsia pulmonar identificou basicamente uma arterite pulmonar característica, inflamação granulomatosa atípica provocada principalmente por vermes e raros ovos de S. mansoni envolvidos por escassa reação inflamatória. Para explicar a origem de constelação clínica toxi-infectuosa, foram afastadas as hipóteses de associação da esquistossomose a concausas infectuosas ou não, mas de curso febril, e a superposição de uma forma toxêmica sobre outra crônica pré-existente. Com base em dados clínicos, particularmente em subsídios da laparoscopia, e anatômicos, concluiu-se tratar o caso de uma forma crônica de esquistossomose reativada, provavelmente em virtude de alterações imunológicas inusitadas do hospedeiro. Ao que tudo parece indicar, o desvio de ovos e de vermes aos pulmões deveu-se à sindrome de hipertensão portal, cujos shunts entre a circulação portal e sistêmica determinaram a rota preferencial da migração.The Authors relate a case ofsevere schistosomiasis mansoni (hepatic form, with portal hypertension, associated with pulmonary form, with pulmonary hypertension and cor pulmonale, o ver which develloped a severe toxi-infectious syndrome of long duration. Serial chest X-rays showed that the arteriolae were predominantly affected, besides a gross and difuse pulmonary micronodulation in both hemithoraces, and pulmonary heart configuration. Histopathology of the pulmonary biopsy material identified basically a

  15. Using residual stacking to mitigate site-specific errors in order to improve the quality of GNSS-based coordinate time series of CORS

    Science.gov (United States)

    Knöpfler, Andreas; Mayer, Michael; Heck, Bernhard

    2014-05-01

    Within the last decades, positioning using GNSS (Global Navigation Satellite Systems; e.g., GPS) has become a standard tool in many (geo-) sciences. The positioning methods Precise Point Positioning and differential point positioning based on carrier phase observations have been developed for a broad variety of applications with different demands for example on accuracy. In high precision applications, a lot of effort was invested to mitigate different error sources: the products for satellite orbits and satellite clocks were improved; the misbehaviour of satellite and receiver antennas compared to an ideal antenna is modelled by calibration values on absolute level, the modelling of the ionosphere and the troposphere is updated year by year. Therefore, within processing of data of CORS (continuously operating reference sites), equipped with geodetic hardware using a sophisticated strategy, the latest products and models nowadays enable positioning accuracies at low mm level. Despite the considerable improvements that have been achieved within GNSS data processing, a generally valid multipath model is still lacking. Therefore, site specific multipath still represents a major error source in precise GNSS positioning. Furthermore, the calibration information of receiving GNSS antennas, which is for instance derived by a robot or chamber calibration, is valid strictly speaking only for the location of the calibration. The calibrated antenna can show a slightly different behaviour at the CORS due to near field multipath effects. One very promising strategy to mitigate multipath effects as well as imperfectly calibrated receiver antennas is to stack observation residuals of several days, thereby, multipath-loaded observation residuals are analysed for example with respect to signal direction, to find and reduce systematic constituents. This presentation will give a short overview about existing stacking approaches. In addition, first results of the stacking approach

  16. Investigation on Bond-Slip Behavior of Z-Pin Interfaces in X-Cor® Sandwich Structures Using Z-Pin Pull-Out Test

    Science.gov (United States)

    Shan, Hangying; Xiao, Jun; Chu, Qiyi

    2018-05-01

    The Z-Pin interfacial bond properties play an important role in the structural performance of X-Cor® sandwich structures. This paper presents an experimental investigation on bond-slip behavior of Z-Pin interfaces using Z-Pin pull-out test. Based on the experimental data the whole Z-Pin pull-out process consists of three stages: initial bonding, debonding and frictional sliding. Comparative experimental study on the influence of design parameters on bond-slip behavior of Z-Pin interfaces has also been performed. Numerical analyses were conducted with the ABAQUS finite element (FE) program to simulate the Z-Pins bond-slip response of the pull-out test. The Z-Pins interfacial bond-slip behavior was implemented using nonlinear spring elements characterized with the constitutive relation from experimental results. Numerical results were validated by comparison with experimental data, and reasonably good agreement was achieved between experimental and analytical pull-out force-slip curves.

  17. Avaliação do desempenho hemodinâmico do dispositivo de assistência ventricular InCor como substituto do coração esquerdo Analysis of the hemodynamic performance of the InCor ventricular assist device as a substitute for the left heart

    Directory of Open Access Journals (Sweden)

    Anderson BENÍCIO

    1999-07-01

    Full Text Available FUNDAMENTO: A assistência circulatória mecânica é uma opção terapêutica em casos de choque cardiogênio refratário ao tratamento farmacológico, sendo freqüentemente utilizada como ponte para o transplante cardíaco. OBJETIVO: Avaliar o desempenho do Dispositivo de Assistência Ventricular (DAV desenvolvido pela Bioengenharia do Instituto do Coração, quando implantado com substituto do coração esquerdo. CASUÍSTICA E MÉTODOS: Foram estudados 10 bezerros da raça Girolando com peso médio de 73 kg. O implante DAV-InCor foi realizado com a cânula de drenagem posicionada no átrio esquerdo (AE ou na ponta do ventrículo esquerdo (VE e a cânula de reposição implantada na aorta torácica descendente. As pressões do coração direito e esquerdo, débito cardíaco e o fluxo do DAV foram determinados antes e após a indução farmacológica de insuficiência miocárdica, na vigência de diferentes níveis de vácuo do sistema de drenagem. RESULTADOS: Com a drenagem no AE, os valores do fluxo do DAV foram de 2,2 ± 0,5 l/min na condição sem vácuo, 3,7 ± 0,4 l/min com vácuo de 10 mmHg, de 4,3 ± 0,4 com vácuo de 20 mmHg e de 4,8 ± 0,6 com vácuo de 30 mmHg. Os valores da pressão de AE foram de 11,7 ± 6; 9,8 ± 5,3, 8,5 ± 4,4 e 5,6 ± 3,3 mmHg nas mesmas condições, respectivamente. Com a cânula ventricular, o fluxo DAV foi de 4,2 ± 0,6 na condição sem vácuo e de 4,4 ± 0,7 com vácuo de 10 mmHg, sendo observados valores de pressão de AE de 11,1 ± 2 e 10,3 ± 3,5 mmHg nas duas condições. Esses resultados foram observados em condições hemodinâmicas semelhantes, sendo o fluxo do DAV responsável por um porcentual maior do débito cardíaco total conforme o nível de vácuo. Esse porcentual foi de 86 ± 13% com a cânula atrial e vácuo de 30 mmHg e de 97 ± 3% com a drenagem ventricular e vácuo de 10 mmHg. CONCLUSÕES: O DAV-InCor mostrou-se eficiente como substituto do ventrículo esquerdo. O desempenho deste

  18. Saint-André-des-Eaux (Côtes-d’Armor : nouveaux éléments sur l’église et sur ses décors peints

    Directory of Open Access Journals (Sweden)

    Mathias Dupuis

    2009-09-01

    Full Text Available Nous avions déjà présenté dans le précédent numéro du Bulletin du Centre d'études médiévales d’Auxerre les premières recherches sur l’ancienne église paroissiale de Saint-André-des-Eaux . La réalisation de sondages en juin 2008 ainsi qu’une dernière série d’observations sur le bâti, préalables à la consolidation des murs de l’église et des vestiges de peintures murales, permettent désormais de mieux cerner l’histoire monumentale de cet édifice et de ses décors peints.Quatre sondages ont été o...

  19. Cor, capacidade de retenção de água e maciez da carne de cordeiro maturada e injetada com cloreto de cálcio Colour, water holding capacity and tenderness of lamb aged and injected with calcium chloride

    Directory of Open Access Journals (Sweden)

    N.M.B.L. Zeola

    2007-08-01

    Full Text Available Os músculos Biceps femoris, Longissimus e Triceps brachii submetidos aos efeitos do tempo de maturação e da injeção com cloreto de cálcio de cordeiros Morada Nova foram estudados quanto às características de cor, capacidade de retenção de água e maciez. Os cordeiros foram abatidos ao atingirem 25kg de peso vivo. Os músculos apresentaram diferenças na cor (luminosidade-L*, teor de vermelho-a* e teor de amarelo-b* 24 horas após o abate. A maturação tendeu a escurecer a carne. O cloreto de cálcio não modificou a cor das carnes provenientes dos músculos Longissimus e Triceps brachii, entretanto as do Biceps femoris apresentaram-se mais vermelhas quando receberam cloreto de cálcio. Quanto à capacidade de retenção de água, a maturação afetou as carnes do Triceps brachii, mas não influenciou as carnes dos músculos Biceps femoris e Longissimus. O cloreto de cálcio não modificou a capacidade de retenção de água dos músculos avaliados. A maturação influiu sobre a maciez do Biceps femoris e do Longissimus.Biceps femoris, Longissimus and Triceps brachii muscles from Morada Nova lambs were submitted to ageing and calcium chloride injection. Colour, water holding capacity and tenderness were studied. Lambs were slaughtered weighting 25kg.. The muscles presented differences in colour (lightness-L*, redness-a* and yellowness- b* 24 hours after rigor mortis instalation. Ageing intensified redness of the meats. Calcium chloride did not modify the colour of Longissimus and Triceps brachii, however, Biceps femoris became more redness after receiving calcium chloride. In relation to water holding capacity, ageing affected meats from Triceps brachii. However, it did not affect Biceps femoris and Longissimus. The calcium chloride didn't modify the water holding capacity of the muscles. Ageing influenced tenderness of Biceps femoris and Longissimus.

  20. Incidência comparativa da apendicite aguda em população miscigenada, de acordo com a cor da pele Comparative incidence of acute appendicitis in a mixed population, related to the skin color

    Directory of Open Access Journals (Sweden)

    Andy Petroianu

    2004-03-01

    Full Text Available RACIONAL: Apendicite aguda é uma emergência cirúrgica muito comum, mas sua etiopatogenia ainda permanece incompreendida. OBJETIVO: Avaliar aspectos epidemiológicos da apendicite aguda relacionados à cor da pele, sexo e idade. MÉTODOS: Foram estudados 500 pacientes operados de apendicite aguda e outros 500 doentes aleatórios tratados por diferentes doenças no Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, MG. Avaliaram-se sexo, idade e cor da pele. Os resultados foram comparados por meio do teste qui-quadrado. RESULTADOS: Significativa prevalência de pacientes leucodérmicos (73,8% foi verificada nessas séries. Não houve predominância por sexo. O número de homens leucodérmicos com apendicite aguda foi significativamente maior do que homens leucodérmicos do grupo-controle. A incidência de melanodérmicos com apendicite foi significativamente menor do que a de pacientes negros do grupo-controle. A idade média da apendicite aguda foi de 23,2 anos para os pacientes leucodérmicos e de 32,3 anos para os melanodérmicos. CONCLUSÕES: Foi nítida a relação entre apendicite aguda com a cor branca da pele.BACKGROUND: Acute appendicitis is a very common surgical emergency, but its etiology and pathology remain incompletely understood. OBJECTIVE: To elucidate epidemiological aspects of acute appendicitis related to skin color, gender and age. METHODS: Five-hundred patients operated on for acute appendicitis, and other 500 patients treated for different diseases and considered as a control group were studied at "Hospital das Clínicas", Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. Gender, age and skin color were investigated. The results were compared by chi-square test. RESULTS: There was no prevalence related to gender. A significant prevalence of white patients (73.8% was verified in this series. The number of white men with appendicitis was significantly higher than white men in the

  1. A cost-effective intelligent robotic system with dual-arm dexterous coordination and real-time vision

    Science.gov (United States)

    Marzwell, Neville I.; Chen, Alexander Y. K.

    1991-01-01

    Dexterous coordination of manipulators based on the use of redundant degrees of freedom, multiple sensors, and built-in robot intelligence represents a critical breakthrough in development of advanced manufacturing technology. A cost-effective approach for achieving this new generation of robotics has been made possible by the unprecedented growth of the latest microcomputer and network systems. The resulting flexible automation offers the opportunity to improve the product quality, increase the reliability of the manufacturing process, and augment the production procedures for optimizing the utilization of the robotic system. Moreover, the Advanced Robotic System (ARS) is modular in design and can be upgraded by closely following technological advancements as they occur in various fields. This approach to manufacturing automation enhances the financial justification and ensures the long-term profitability and most efficient implementation of robotic technology. The new system also addresses a broad spectrum of manufacturing demand and has the potential to address both complex jobs as well as highly labor-intensive tasks. The ARS prototype employs the decomposed optimization technique in spatial planning. This technique is implemented to the framework of the sensor-actuator network to establish the general-purpose geometric reasoning system. The development computer system is a multiple microcomputer network system, which provides the architecture for executing the modular network computing algorithms. The knowledge-based approach used in both the robot vision subsystem and the manipulation control subsystems results in the real-time image processing vision-based capability. The vision-based task environment analysis capability and the responsive motion capability are under the command of the local intelligence centers. An array of ultrasonic, proximity, and optoelectronic sensors is used for path planning. The ARS currently has 18 degrees of freedom made up by two

  2. 77 FR 19112 - Final Flood Elevation Determinations

    Science.gov (United States)

    2012-03-30

    ... Township of Lima, River. Township of Scio, Township of Webster, Village of Dexter. Just upstream of North... Webster Maps are available for inspection at 5665 Webster Church Road, Dexter, MI 48130. Village of Barton... Dexter Maps are available for inspection at 6880 Dexter-Pinckney Road, Dexter, MI 48130. Meeker County...

  3. "Estimativa da produção primária e biomassa fitoplanctônica através de sensoriamento remoto da cor do oceano e dados in situ na Costa Sudeste Brasileira"

    OpenAIRE

    Milton Kampel

    2003-01-01

    A biomassa e a produtividade primária fitoplanctônica da costa sudeste foram estimadas através de sensoriamento remoto da cor do oceano e dados in situ. Foram realizados quatro cruzeiros hidrográficos sazonais de mesoescala nas regiões de plataforma e talude continental durante os verões e invernos de 2001 e 2002. Com a descrição das características hidrográficas e distribuições de nutrientes inorgânicos dissolvidos, complementada pela análise de imagens orbitais (AVHRR e SeaWiFS), foi possív...

  4. Vasculopatia polipoidal idiopática da coróide: aspectos extremos da evolução da doença em um paciente - Relato de caso Idiopathic polypoidal choroidal vasculopathy: its extreme aspects in one patient - Case report

    Directory of Open Access Journals (Sweden)

    Ieda Maria Alexandre Barreira

    2005-04-01

    Full Text Available O artigo descreve um caso de vasculopatia polipoidal idiopática da coróide (VPIC e demonstra o papel relevante da indocianinografia no diagnóstico diferencial com outras causas de neovascularização subretiniana, particularmente degeneração macular relacionada à idade (DMRI, bem como avalia os aspectos extremos na evolução da doença em um único paciente. Paciente de 54 anos, sexo masculino, cor parda, com queixas de baixa de acuidade visual súbita em OD, foi submetido a exame oftalmológico, pelo qual se constatou hemorragia vítrea em OD e, posteriormente, descolamento sero-hemorrágico do epitélio pigmentário da retina em OE. A angiofluoresceinografia e indocianinografia mostraram quadro compatível com vasculopatia polipoidal idiopática da coróide. O paciente foi submetido a vitrectomia via pars plana em OD e foi acompanhado por período de 5 meses, evoluindo com perda de visão secundária a descolamento de retina e cicatriz macular disciforme em OD. No olho contralateral, ocorreu involução da vasculopatia com preservação de acuidade visual 20/25. A vasculopatia polipoidal idiopática da coróide é entidade clínica cujas anormalidades do fundo de olho se sobrepõem às manifestações da degeneração macular relacionada à idade exsudativa. A indocianinografia é de vital importância no diagnóstico diferencial entre as duas doenças que tem evolução e prognóstico distintos. Além disso, consideramos este caso muito ilustrativo pelas diferentes nuances com que a doença se manifestou e evoluiu em um único paciente.To describe a case of idiopathic polypoidal choroidal vasculopathy and the role of indocyanine green angiography findings in the differential diagnosis of exsudative maculopathies, particularly with age-related macular degeneration, and the extreme evolution of idiopathic polypoidal choroidal vasculopathy in one patient. A patient with vitreous hemorrhage was examined and evaluated by fluorescein and

  5. Modeling spatial and temporal variations in temperature and salinity during stratification and overturn in Dexter Pit Lake, Tuscarora, Nevada, USA

    Science.gov (United States)

    Balistrieri, L.S.; Tempel, R.N.; Stillings, L.L.; Shevenell, L.A.

    2006-01-01

    This paper examines the seasonal cycling of temperature and salinity in Dexter pit lake in arid northern Nevada, and describes an approach for modeling the physical processes that operate in such systems. The pit lake contains about 596,200 m3 of dilute, near neutral (pHs 6.7-9) water. Profiles of temperature, conductivity, and selected element concentrations were measured almost monthly during 1999 and 2000. In winter (January-March), the pit lake was covered with ice and bottom water was warmer (5.3 ??C) with higher total dissolved solids (0.298 g/L) than overlying water (3.96 ??C and 0.241 g/L), suggesting inflow of warm (11.7 ??C) groundwater with a higher conductivity than the lake (657 versus 126-383 ??S/cm). Seasonal surface inflow due to spring snowmelt resulted in lower conductivity in the surface water (232-247 ??S/cm) relative to deeper water (315-318 ??S/cm). The pit lake was thermally stratified from late spring through early fall, and the water column turned over in late November (2000) or early December (1999). The pit lake is a mixture of inflowing surface water and groundwater that has subsequently been evapoconcentrated in the arid environment. Linear relationships between conductivity and major and some minor (B, Li, Sr, and U) ions indicate conservative mixing for these elements. Similar changes in the elevations of the pit lake surface and nearby groundwater wells during the year suggest that the pit lake is a flow-through system. This observation and geochemical information were used to configure an one-dimensional hydrodynamics model (Dynamic Reservoir Simulation Model or DYRESM) that predicts seasonal changes in temperature and salinity based on the interplay of physical processes, including heating and cooling (solar insolation, long and short wave radiation, latent, and sensible heat), hydrologic flow (inflow and outflow by surface and ground water, pumping, evaporation, and precipitation), and transfers of momentum (wind stirring

  6. Modeling spatial and temporal variations in temperature and salinity during stratification and overturn in Dexter Pit Lake, Tuscarora, Nevada, USA

    International Nuclear Information System (INIS)

    Balistrieri, Laurie S.; Tempel, Regina N.; Stillings, Lisa L.; Shevenell, Lisa A.

    2006-01-01

    This paper examines the seasonal cycling of temperature and salinity in Dexter pit lake in arid northern Nevada, and describes an approach for modeling the physical processes that operate in such systems. The pit lake contains about 596,200 m 3 of dilute, near neutral (pHs 6.7-9) water. Profiles of temperature, conductivity, and selected element concentrations were measured almost monthly during 1999 and 2000. In winter (January-March), the pit lake was covered with ice and bottom water was warmer (5.3 deg. C) with higher total dissolved solids (0.298 g/L) than overlying water (3.96 deg. C and 0.241 g/L), suggesting inflow of warm (11.7 deg. C) groundwater with a higher conductivity than the lake (657 versus 126-383 μS/cm). Seasonal surface inflow due to spring snowmelt resulted in lower conductivity in the surface water (232-247 μS/cm) relative to deeper water (315-318 μS/cm). The pit lake was thermally stratified from late spring through early fall, and the water column turned over in late November (2000) or early December (1999). The pit lake is a mixture of inflowing surface water and groundwater that has subsequently been evapoconcentrated in the arid environment. Linear relationships between conductivity and major and some minor (B, Li, Sr, and U) ions indicate conservative mixing for these elements. Similar changes in the elevations of the pit lake surface and nearby groundwater wells during the year suggest that the pit lake is a flow-through system. This observation and geochemical information were used to configure an one-dimensional hydrodynamics model (Dynamic Reservoir Simulation Model or DYRESM) that predicts seasonal changes in temperature and salinity based on the interplay of physical processes, including heating and cooling (solar insolation, long and short wave radiation, latent, and sensible heat), hydrologic flow (inflow and outflow by surface and ground water, pumping, evaporation, and precipitation), and transfers of momentum (wind

  7. Esquistossomose pulmonar. II. Forma crônica reativada com hipertensão e Cor pulmonale

    Directory of Open Access Journals (Sweden)

    Jayme Neves

    1980-12-01

    Full Text Available Os Autores descrevem um caso grave de esquistossomose mansoni (forma hepática com hipertensão portal associada a forma pulmonar com hipertensão pulmonar e cor pulmonalej sobre o qual evoluiu uma sindrome toxi-infectuosa grave e de longa duração. Sucessivos exames radiológicos do tórax revelaram acometimento predominantemente arteriolar, ao lado de uma micronodulação pulmonar grosseira e difusa em ambos os hemitóraces e configuração de coração pulmonar. A histopatologia de material de biópsia pulmonar identificou basicamente uma arterite pulmonar característica, inflamação granulomatosa atípica provocada principalmente por vermes e raros ovos de S. mansoni envolvidos por escassa reação inflamatória. Para explicar a origem de constelação clínica toxi-infectuosa, foram afastadas as hipóteses de associação da esquistossomose a concausas infectuosas ou não, mas de curso febril, e a superposição de uma forma toxêmica sobre outra crônica pré-existente. Com base em dados clínicos, particularmente em subsídios da laparoscopia, e anatômicos, concluiu-se tratar o caso de uma forma crônica de esquistossomose reativada, provavelmente em virtude de alterações imunológicas inusitadas do hospedeiro. Ao que tudo parece indicar, o desvio de ovos e de vermes aos pulmões deveu-se à sindrome de hipertensão portal, cujos shunts entre a circulação portal e sistêmica determinaram a rota preferencial da migração.

  8. Transference of lutein during cheese making, color stability, and sensory acceptance of prato cheese Transferência de luteína na fabricação de queijo prato, estabilidade da cor e aceitação sensorial

    Directory of Open Access Journals (Sweden)

    Mirian Tiaki Kaneiwa Kubo

    2013-02-01

    Full Text Available The consumption of lutein is associated with the prevention and reduction of age-related macular degeneration. Its incorporation into Prato cheese as a yellowish food coloring is a valid alternative to increase the daily intake of this compound. However, part of the lutein added may be lost in the whey during the cheese making, or it can be degraded by light during storage, resulting in color changes reducing the sensory acceptance of the cheese. The objectives of this study were to determine the transference of the lutein (dye, added to the milk, in the whey, and cheese, to evaluate the effect of the lutein addition, light exposure, and storage time on the cheese color, and to verify the sensory acceptance of Prato cheese with addition of lutein. The lutein recovery of cheese was 95.25%. Color saturation (chrome increased during storage time resulting in a cheese with more intense color, but there were no changes in the hue of the cheese. Adjusting the amount of lutein added to Prato cheese may lead to greater acceptance. The high recovery of lutein in the cheese and the fact that the hue remained unchanged during storage under light showed that the incorporation of lutein into Prato cheese is feasible from a technical point of view.A ingestão de luteína está associada à prevenção e redução da degeneração macular relacionada à idade e a sua adição em queijo Prato, como corante de tom amarelado, é uma alternativa válida para aumentar a ingestão diária desse composto. Entretanto, parte da luteína adicionada pode ser perdida no soro durante a fabricação do queijo e também, ser degradada pela ação da luz durante armazenamento, resultando em mudanças na cor dos queijos, diminuindo a aceitação sensorial. O objetivo do trabalho foi determinar a transferência do corante luteína, adicionado ao leite, no soro e queijo, avaliar o efeito da adição de luteína, exposição à luz e tempo de armazenamento na cor do queijo e

  9. A cor da morte: causas de óbito segundo características de raça no Estado de São Paulo, 1999 a 2001 The color of death: causes of death according to race in the State of Sao Paulo, 1999 to 2001

    Directory of Open Access Journals (Sweden)

    Luís Eduardo Batista

    2004-10-01

    Full Text Available OBJETIVO: Sob a premissa de que há diferenças sociais segundo a etnia e que essas diferenças se constituem vulnerabilidade para doença, realizou-se estudo para averiguar se a raça/cor condiciona padrões característicos de óbito. MÉTODOS: Pelos registros de óbitos do Estado de São Paulo dos anos de 1999 a 2001, analisou-se a mortalidade proporcional por causa básica, segundo os capítulos da CID-10, entre as categorias de raça ou cor: branca, preta, parda e outras. A tabela de contingência permitiu, além do teste de chi2, a análise de resíduo, que aponta o excesso de óbitos estatisticamente significante, em cada categoria de causa básica e cor. Usou-se a análise de correspondência para a representação gráfica das relações multidimensionais das distâncias chi2 entre as categorias das variáveis estudadas. RESULTADOS: Foram analisados 647.321 registros válidos, sendo 77,7% de brancos, 5,4% de pretos, 14,3% de pardos e 2,6% de outros. Foi encontrada associação significante entre causas de óbito e raça/cor. Observou-se no mapa multidimensional apresentado que pretos e pardos aparecem distantes, ainda que apresentem um perfil de óbito semelhante, ao contrário de brancos e outros que poderiam ser agrupados numa única categoria. À parte as causas mal definidas que caracterizam apenas os óbitos de pretos, as outras causas de óbito desse grupo são comuns a pretos e pardos, variando, no entanto, em ordem de relação e intensidade. CONCLUSÕES: Foi encontrado na análise da mortalidade segundo a raça/cor, que a morte tem cor. Há uma morte branca que tem como causa as doenças, as quais, embora de diferentes tipos, não são mais que doenças. Há uma morte negra que não tem causa em doenças: são as causas externas, complicações da gravidez e parto, os transtornos mentais e as causas mal definidas.OBJECTIVE: Assuming that ethnicity might be a basis for social differentiation and that such differences might

  10. Choroid plexus papilloma and Aicardi syndrome: case report Papiloma do plexo coróideo e síndrome de Aicardi: relato de caso

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    Geraldo Pianetti Filho

    2002-12-01

    Full Text Available A case of Aicardi syndrome associated with a choroid plexus papilloma of the third and both lateral ventricles in a 15 months old baby girl is repported. The tumor was completely removed via three craniotomies. Reports of the literature with the association of choroid plexus papilloma and Aicardi syndrome are rare. We suggest that children diagnosed with Aicardi syndrome should routinely undergo imaging studies of the brain, such as computed tomography or magnetic resonance.Relatamos o caso de uma criança com 15 meses de idade, portadora da síndrome de Aicardi associada a tumores nos ventrículos laterais e terceiro ventrículo (papilomas que foram retirados cirurgicamente através de três craniotomias. A ocorrência de papiloma do plexo coróideo associada à sindrome de Aicardi é raramente descrita na literatura. Sugerimos que as crianças portadoras da síndrome de Aicardi sejam rotineiramente submetidas a estudo radiológico do encéfalo através da tomografia computadorizada ou ressonância nuclear.

  11. Effect of skin colour and selected physical characteristics on Schistosoma mansoni dependent morbidity Efeito da cor da pele e certas características físicas na morbidade dependente de Schistosoma mansoni

    Directory of Open Access Journals (Sweden)

    C. B. Cançado

    1995-12-01

    Full Text Available The effect of the colour group on the morbidity due to Schistosoma mansoni was examined in two endemic areas situated in the State of Minas Gerais, Brazil. Of the 2773 eligible inhabitants, 1971 (71.1% participated in the study: 545 (27.6% were classified as white, 719 (36.5% as intermediate and 707 (35.9% as black. For each colour group, signs and symptoms of individuals who eliminated S.mansoni eggs (cases were compared to those who did not present eggs in the faeces (controls. The odds ratios were adjusted by age, gender, previous treatment for schistosomiasis, endemic area and quality of the household. There was no evidence of a modifier effect of colour on diarrhea, bloody faeces or abdominal pain. A modifier effect of colour on hepatomegaly was evident among those heaviest infected (> 400 epg: the adjusted odds ratios for palpable liver at the middle clavicular and the middle sternal lines were smaller among blacks (5.4 and 6.5, respectively and higher among whites (10.6 and 12.9 and intermediates (10.4 and 10.1, respectively. These results point out the existence of some degree of protection against hepatomegaly among blacks heaviest infected in the studied areas.O efeito da cor na morbidade associada ao Schistosoma mansoni foi estudado em duas áreas endêmicas situadas no Estado de Minas Gerais, Brasil. Dos 2773 habitantes elegíveis, 1971 (71,1% participaram do estudo: 545 (27,6% foram classificados como brancos, 719 (36,5% como intermediários e 707 (35,9% como negros. Os sinais e sintomas dos indivíduos que eliminavam ovos de S. mansoni nas fezes (casos foram comparados aos daqueles que não apresentavam ovos do parasita neste exame (controles. As razões de chance foram ajustadas por idade, gênero, tratamento anterior para a esquistossomose, área endêmica e qualidade do domicílio. Não houve evidência de um efeito modificador da cor para a ocorrência de diarréia, sangue nas fezes ou dor abdominal. Um efeito modificador da

  12. Encopresis Plus?

    Science.gov (United States)

    Cormier, DePorres; Reilly, Marie; Young, Amy; Augustyn, Marilyn

    Dexter is a 12-year-old boy who presents with his maternal grandmother for follow-up to primary care for secondary encopresis. Dexter presented, 18 months ago, with a 3-month history of secondary encopresis. At that time, a comprehensive assessment revealed functional constipation resulting in encopresis. Dexter's symptoms resolved with a combination of medication management and behavioral strategies; laxatives were discontinued 12 months ago.Dexter's grandmother reports that for the past 6 months, her grandson developed encopresis once again. However, she notes that, although Dexter had small-volume episodes of soiling in the past, he is now passing fully formed stools into his underwear. These episodes usually occur once a day, either at home or at school. Frustrated, Dexter's grandmother has transitioned him to adult diapers.Dexter denies hematochezia, pain, dysuria, hematuria, urinary incontinence, dietary changes, or weight loss. He passes soft stool in his underwear once daily without blood or pain. When interviewed alone, Dexter denies drug use, depression, or significant social stressors. Surprisingly, he seems unconcerned about depression, drugs and social stress, and frequently laughs when discussing them. His physical examination, including a rectal examination, is normal.Dexter's medical history is notable for attention-deficit hyperactivity disorder, treated with stimulant medication. He was toilet trained at 3 years without any difficulty. He lives with his grandmother, who is his legal guardian; his mother has chronic mental health problems and substance abuse. Dexter maintains regular contact with his mother and reports that their relationship is positive.Dexter's grandmother is extremely distressed by his current presentation and notably, Dexter is not. What would you do next?

  13. Cor do solo: uma abordagem da forma convencional de obtenção em oposição à automatização do método para fins de classificação de solos Soil color: approach to a conventional assessment method in comparison to an automatization process for soil classification

    Directory of Open Access Journals (Sweden)

    R. C. Campos

    2004-10-01

    Full Text Available A cor é amplamente reconhecida como uma medida primária identificadora de solos. Propriedades físicas, químicas e mineralógicas de solos podem ser derivadas de sua cor. O enquadramento de algumas classes de solos, já no segundo nível categórico do atual Sistema Brasileiro de Classificação de solos, requer que a cor da amostra do horizonte diagnóstico seja determinada por comparação com os padrões existentes na escala de Munsell. Este processo de classificação é extremamente subjetivo e consome tempo, limitando a exatidão, a transferência e a utilização do procedimento. O principal objetivo deste trabalho foi obter a cor do solo com o método convencional e com um colorímetro, a fim de avaliar as possíveis implicações na classificação de solos. Cinco pedólogos foram convidados a classificar o matiz de 80 amostras de solo pela comparação com a carta de Munsell. Em seguida, o matiz das amostras foi obtido com um colorímetro, também na notação de Munsell. Pelas análises estatísticas foram avaliados: coeficientes de correlação, índice de precisão (IP, forma de agrupamento e tendências médias entre as determinações de matiz. Coeficientes de correlação variando de 0,68 a 0,94 entre as determinações de cor demonstraram que os pedólogos produziram dados que validaram o estudo. No entanto, houve confirmação de que as medidas realizadas por pedólogos não coincidiram, sendo diferentes também das determinações feitas pelo colorímetro. Índices de Precisão (IP indicaram haver concordância em apenas 8,75 % das determinações em amostras úmidas e 17,5 % nas amostras secas. Ocorreram divergências na determinação do matiz das amostras que resultariam em erros na classificação dos solos. A avaliação das tendências médias indicou que os pesquisadores superestimaram as determinações de cor realizadas pelo colorímetro, resultando em alterações na classificação de solos.Soil color is widely

  14. Mapeamento do fósforo adsorvido por meio da cor e da suscetibilidade magnética do solo

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    Rafael Gonçalves Peluco

    2015-03-01

    Full Text Available O objetivo deste trabalho foi avaliar a possibilidade de se mapear o fósforo adsorvido por meio da avaliação da cor e da suscetibilidade magnética do solo. O experimento foi realizado em área de cana-de-açúcar com 380 ha, que compreendia quatro tipos de Latossolos, com diferentes texturas e fertilidades naturais. Foram coletadas 241 amostras de solo, na profundidade de 0,00-0,25 m. O índice de avermelhamento do solo foi calculado a partir dos valores de matiz, valor e croma das amostras, obtidos com espectroscopia de reflectância difusa. Foram ajustados modelos de regressão entre o fósforo adsorvido e a suscetibilidade magnética ou o índice de avermelhamento dos solos. A dependência espacial dos dados foi avaliada por meio de geoestatística. A suscetibilidade magnética correlaciona-se significativamente ao fósforo adsorvido, o que possibilita seu uso como componente de funções de pedotransferência para quantificação indireta do fósforo adsorvido ao solo. O índice de avermelhamento e a suscetibilidade magnética apresentam dependência espacial com o fósforo adsorvido. A suscetibilidade magnética e o índice de avermelhamento dos solos, avaliado pela espectroscopia de reflectância difusa, podem auxiliar no mapeamento e na identificação de áreas com diferentes potenciais de adsorção de fósforo.

  15. Comparison of functional recovery of manual dexterity after unilateral spinal cord lesion or motor cortex lesion in adult macaque monkeys

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    Florence eHoogewoud

    2013-07-01

    Full Text Available In relation to mechanisms involved in functional recovery of manual dexterity from cervical cord injury or from motor cortical injury, our goal was to determine whether the movements that characterize post-lesion functional recovery are comparable to original movement patterns or do monkeys adopt distinct strategies to compensate the deficits depending on the type of lesion? To this aim, data derived from earlier studies, using a skilled finger task (the modified Brinkman board from which pellets are retrieved from vertical or horizontal slots, in spinal cord and motor cortex injured monkeys were analyzed and compared. Twelve adult macaque monkeys were subjected to a hemi-section of the cervical cord (n=6 or to a unilateral excitotoxic lesion of the hand representation in the primary motor cortex (n=6. In addition, in each subgroup, one half of monkeys (n=3 were treated for 30 days with a function blocking antibody against the neurite growth inhibitory protein Nogo-A, while the other half (n=3 represented control animals. The motor deficits, and the extent and time course of functional recovery were assessed.For some of the parameters investigated (wrist angle for horizontal slots and movement types distribution for vertical slots after cervical injury; movement types distribution for horizontal slots after motor cortex lesion, post-lesion restoration of the original movement patterns (true recovery led to a quantitatively better functional recovery. In the motor cortex lesion groups, pharmacological reversible inactivation experiments showed that the peri-lesion territory of the primary motor cortex or re-arranged, spared domain of the lesion zone, played a major role in the functional recovery, together with the ipsilesional intact premotor cortex.

  16. Estimation of leaf area index for cotton canopies using the LI-COR LAI-2000 plant canopy analyzer

    International Nuclear Information System (INIS)

    Hicks, S.K.; Lascano, R.J.

    1995-01-01

    Measurement of leaf area index (LAI) is useful for understanding cotton (Gossypium hirsutum L.) growth, water use, and canopy light interception. Destructive measurement is time consuming and labor intensive. Our objective was to evaluate sampling procedures using the Li-Cor (Lincoln, NE) LAI 2000 plant canopy analyzer (PCA) for nondestructive estimation of cotton LAI on the southern High Plains of Texas. We evaluated shading as a way to allow PCA measurements in direct sunlight and the influence of solar direction when using this procedure. We also evaluated a test of canopy homogeneity (information required for setting PCA field of view), determined the number of below-canopy measurements required, examined the influence of leaf wilting on PCA LAI determinations, and tested an alternative method (masking the sensor's two outer rings) for calculating LAI from PCA measurements. The best agreement between PCA and destructively measured LAI values was obtained when PCA observations were made either during uniformly overcast conditions or around solar noon using the shading method. Heterogeneous canopies with large gaps between rows required both a restricted (45 degrees) azimuthal field of view and averaging the LAI values for two transects, made with the field of view parallel and then perpendicular to the row direction. This method agreed well (r2 = 0.84) with destructively measured LAI in the range of 0.5 to 3.5 and did not deviate from a 1:1 relationship. The PCA underestimated LAI by greater than or equal 20% when measurements were made on canopies wilted due to water stress. Masking the PCA sensor's outer rings did not improve the relationship between estimated and measured LAI in the range of LAI sampled

  17. Component-resolved in vitro diagnosis of hazelnut allergy in Europe

    DEFF Research Database (Denmark)

    Hansen, Kirsten Skamstrup; Ballmer-Weber, Barbara K; Sastre, Joaquin

    2009-01-01

    BACKGROUND: Food allergy to hazelnut occurs both with and without concomitant pollen allergy. OBJECTIVE: We sought to evaluate a panel of hazelnut allergens for diagnosis of hazelnut allergy in Spain, Switzerland, and Denmark. METHODS: Fifty-two patients with a positive double-blind, placebo......-controlled food challenge result with hazelnuts; 5 patients with a history of anaphylaxis; 62 patients with pollen allergy but hazelnut tolerance; and 63 nonatopic control subjects were included. Serum IgE levels to hazelnut extract, recombinant hazelnut allergens (rCor a 1.04, rCor a 2, rCor a 8, rCor a 11......), and native allergens (nCor a 9, nCor a Bd8K, nCor a Bd11K) were analyzed by means of ImmunoCAP. RESULTS: Among patients with hazelnut allergy, 91% (Switzerland/Spain, 100%; Denmark, 75%) had IgE to hazelnut extract, 75% to rCor a 1.04, 42% to rCor a 2, 28% to rCor a 8, and 2% to rCor a 11. The highest rate...

  18. Guilhem de Saint Gregori, "Ben grans avolesa intra" (BdT 233.2; Bartolomeo Zorzi, "En tal dezir mos cors intra" (BdT 74.4

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    Alessandro Bampa

    2014-02-01

    Full Text Available This paper provides a commentary and translation of two contrafacta of Arnaut Daniel’s sestina: Guilhem de Saint Gregori’s "Ben gran avolesa intra" and Bartolomeo Zorzi’s "En tal dezir mos cors intra". For the first song, I will highlight the new contexts and meanings given to Arnaut’s images (which are taken from his sestina and other poems within Guilhem’s invective against Aimers II of Poitiers, in order to evaluate its literary qualities and innovations. Through lexical analysis, this paper will reveal the strong connection between Zorzi’s and Guilhem’s songs. In particular, the paper analyses specifically their common theme of Hell, suggesting Bartolomeo’s text is most likely an answer to Arnaut’s sestina, which clearly expresses a desire of sensual pleasure. The study pays particular attention to the relation between sexual love and the matter of eternal damnation: Zorzi attacks Arnaut’s ferm voler, advancing his argument by evoking Chrétien de Troyes’ "Perceval" (references to which are spread throughout the text, and not only in l. 18 and through his constant stress on the duties towards one’s family.

  19. Cor, gênero e classe: dinâmicas da discriminação entre jovens de grupos populares cariocas Color, gender and social class: dynamics of discrimination of lower income youth from Rio de Janeiro

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    Simone Monteiro

    2009-06-01

    Full Text Available Este trabalho discute as dinâmicas de discriminação entre moças e rapazes das camadas populares do Rio de Janeiro, considerando o papel que as hierarquias de cor/raça, gênero e classe social desempenham na configuração das práticas sociais. A análise tem por base entrevistas em profundidade com 42 jovens, de 18 a 24 anos. As situações de discriminação são referidas com maior frequência pelos rapazes. Entre os homens tais experiências estão associadas principalmente aos espaços públicos e ao mercado de trabalho, enquanto entre as mulheres a discriminação está mais vinculada aos espaços privados e ao local de moradia. Os dados estimulam uma discussão sobre a heterogeneidade das experiências de discriminação, na qual a cor/raça está associada às condições sociais e às relações de gênero.This work discuss the dynamics of discrimination of lower income male and female youths from Rio de Janeiro, considering the impact of the color/race, gender and social class hierarchies in the configurations of social practices. The analysis is based on in-depth interviews of 42 young people from 18 to 24 years of age. Situations of discrimination are much more referred to by men. The public spaces and the labor market are cited mainly by the boys. In the girls' view the discrimination is more associated to the place of residence and the private sphere. These data stimulate an analysis about the heterogeneity of the experiences of discrimination, where color/race is associated to social condition and gender relations.

  20. Acoustic analysis of prosody in Sydenham's chorea Análise acústica da prosódia em coréia de Sydenham

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    Patrícia M Oliveira

    2010-10-01

    Full Text Available There are few studies of language and speech in patients with Sydenham's chorea (SC. We have done an acoustic analysis of fundamental frequency (F0, duration and intensity of declarative and interrogative sentences made by 20 SC patients, 20 patients with rheumatic fever (RF without chorea, and compared them with 20 healthy age-matched controls (CO. Each group included 12 females. We found that there is no difference between the RF and CO groups in all studied parameters. Patients with SC, however, presented with a speech characterized by decreased F0 range (difference between minimum and maximum F0, shorter duration of sentences, and higher intensity of the first syllable of sentences. The findings were not influenced by the nature of the sentences (i.e. , declarative or interrogative, but for all variables they were significantly more severe in males than females. In conclusion, we have demonstrated that patients with acute SC have an impairment of modulation of F0 and longer duration of emission of sentences, resulting in a monotone and slow speech. This pattern is similar to what has been described in other basal ganglia illnesses, such as Parkinson's disease, Huntington's disease and Wilson's disease.Há poucos estudos sobre linguagem e fala em pacientes com coréia de Sydenham (CS. Fizemos uma análise acústica da freqüência fundamental (F0, duração e intensidade de sentenças declarativas e interrogativas feitas por 20 pacientes com CS, 20 pacientes com febre reumática (FR sem coréia, comparando-os com 20 controles saudáveis e pareados por idade (CO. Cada grupo incluiu 12 mulheres. Foi encontrado que não há diferença entre os grupos FR e CO quanto a todos parâmetros estudados. Pacientes com CS, contudo, apresentaram-se com fala caracterizada pela redução da variação de F0 (diferença entre F0 mínima e máxima, duração mais curta das sentenças e maior intensidade da primeira sílaba das sentenças. Os achados não foram

  1. Improving the use of principal component analysis to reduce physiological noise and motion artifacts to increase the sensitivity of task-based fMRI.

    Science.gov (United States)

    Soltysik, David A; Thomasson, David; Rajan, Sunder; Biassou, Nadia

    2015-02-15

    Functional magnetic resonance imaging (fMRI) time series are subject to corruption by many noise sources, especially physiological noise and motion. Researchers have developed many methods to reduce physiological noise, including RETROICOR, which retroactively removes cardiac and respiratory waveforms collected during the scan, and CompCor, which applies principal components analysis (PCA) to remove physiological noise components without any physiological monitoring during the scan. We developed four variants of the CompCor method. The optimized CompCor method applies PCA to time series in a noise mask, but orthogonalizes each component to the BOLD response waveform and uses an algorithm to determine a favorable number of components to use as "nuisance regressors." Whole brain component correction (WCompCor) is similar, except that it applies PCA to time-series throughout the whole brain. Low-pass component correction (LCompCor) identifies low-pass filtered components throughout the brain, while high-pass component correction (HCompCor) identifies high-pass filtered components. We compared the new methods with the original CompCor method by examining the resulting functional contrast-to-noise ratio (CNR), sensitivity, and specificity. (1) The optimized CompCor method increased the CNR and sensitivity compared to the original CompCor method and (2) the application of WCompCor yielded the best improvement in the CNR and sensitivity. The sensitivity of the optimized CompCor, WCompCor, and LCompCor methods exceeded that of the original CompCor method. However, regressing noise signals showed a paradoxical consequence of reducing specificity for all noise reduction methods attempted. Published by Elsevier B.V.

  2. Manual Performance Deterioration in the Cold

    NARCIS (Netherlands)

    Daanen, H.A.M.

    2009-01-01

    Manual performance during military operations in cold and windy climates is severely hampered by decreased dexterity, but valid dexterity decrease predictors based on climatic factors are scarce. Therefore, this study investigated the decrease in finger dexterity for nine combinations of ambient

  3. Tratamento conservador ocular dos melanomas de coróide com braquiterapia utilizando placas de iodo-125 Conservative treatment of choroidal melanomas using iodine brachytherapy

    Directory of Open Access Journals (Sweden)

    Antônio Cássio Assis Pellizzon

    2004-08-01

    Full Text Available OBJETIVO: Avaliar, retrospectivamente, o resultado do tratamento conservador do melanoma de coróide, por meio de braquiterapia, usando placas episclerais de iodo-125 (modelo 6711, Amershan. MATERIAIS E MÉTODOS: Foram avaliados 49 pacientes portadores de melanoma de coróide tratados no Hospital do Câncer, São Paulo, SP, de março de 2001 a janeiro de 2003. Os seguintes parâmetros foram analisados e correlacionados ao controle local e sobrevida: sexo, idade, dimensões da lesão, tempo de tratamento e doses no ápice e base das lesões. RESULTADOS: Com diâmetro máximo da base do tumor de 17 mm e altura máxima de 12 mm, observamos que as doses na base do tumor variaram de 213 a 463 Gy (mediana de 347 Gy e no ápice, de 51 a 250 Gy (mediana de 91 Gy. As taxas de preservação ocular, sobrevida livre de doença e conservação ocular, atuariais em dois anos, foram de 96%, 93,5% e 96,3%, respectivamente. Através de análise univariada, o único fator prognóstico para controle local nesta análise foi a altura do tumor menor que 6 mm (p = 0,0348. CONCLUSÃO: A braquiterapia levou a uma taxa bastante satisfatória de controle local, confirmando que a altura do tumor é um dos fatores prognósticos importantes desse parâmetro.OBJECTIVE: To retrospectively evaluate the results of conservative therapy using episcleral iodine-125 (model 6711, Amershan plaque for brachytherapy of choroidal melanoma. MATERIALS AND METHODS: We evaluated 49 patients with choroidal melanoma treated at "Hospital do Câncer", São Paulo, Brazil, from March 2001 to January 2003. The following clinical parameters were analyzed and correlated with local control and survival rate: gender, age, lesion dimension, treatment duration, as well as doses in apex and base of the tumors. RESULTS: The maximum diameter and height of the base of the tumors treated were 17 mm and 12 mm, respectively. Doses at those points ranged from 213 to 463 Gy (median: 347 Gy and 51 to 250 Gy

  4. Manual performance deterioration in the cold estimated using the wind chill equivalent temperature

    NARCIS (Netherlands)

    Daanen, H.A.M.

    2009-01-01

    Manual performance during work in cold and windy climates is severely hampered by decreased dexterity, but valid dexterity decrease predictors based on climatic factors are scarce. Therefore, this study investigated the decrease in finger- and hand dexterity and grip force for nine combinations of

  5. Prise en charge d’un proche âgé dépendant à domicile en Corée du Sud : recherche sur les aidantes principales de la génération du baby-boom

    OpenAIRE

    Oh, Yoonji

    2017-01-01

    Cadre de la recherche : Si le care (soin) relève du souci de l’autre, ce rôle est le plus souvent considéré comme une qualité féminine. En Corée du Sud, la belle-fille devient souvent l’aidante principale lorsque ses proches âgés ont besoin de soins de longue durée. Objectifs : La présente recherche a pour objectif de montrer le vécu des belles-filles aidantes principales à domicile de leurs proches âgés dépendants (surtout leur belle-mère), et de constater l’invisibilité de leur travail au ...

  6. Efeito de parâmetros de extrusão na cor E propriedades de pasta da farinha de mandioquinha-salsa (Arracacia xanthorrhiza Effect of extrusion parameters on color and pasting properties of peruvian carrot flour (Arracacia xanthorrhiza

    Directory of Open Access Journals (Sweden)

    Bruna Menegassi

    2007-12-01

    Full Text Available Processou-se neste trabalho a farinha de mandioquinha-salsa (Arracacia xanthorrhiza Bancr. em uma linha de extrusão (mono rosca variando as condições operacionais: umidade da farinha (11-19%, temperatura de extrusão (86-154ºC e taxa de rotação da rosca (136-272rpm. Os parâmetros de cor analisados foram luminosidade (L* e os componentes de cromaticidade a* e b*. Os parâmetros de propriedade de pasta analisados foram viscosidade inicial, pico de viscosidade, quebra de viscosidade, tendência a retrogradação e viscosidade final. Os resultados obtidos mostraram que a umidade da matéria-prima interferiu nos componentes de cor das farinhas com efeito significativo sobre a luminosidade e croma a*, e a temperatura interferiu no croma b* . Quanto ao efeito dos parâmetros de processo sobre as propriedades de pasta, a umidade interferiu nas viscosidades inicial e final dos produtos, pico e quebra de viscosidade, enquanto a temperatura de extrusão e a rotação da rosca tiveram influência sobre a tendência a retrogradação e viscosidade final dos produtos.In this work peruvian carrot flour (Arracacia xanthorrhiza Bancr. was processed in a single screw extruder at different moisture contents (11-19%, extrusion temperature (86-154ºC and screw speed (136-272rpm. The parameters L*, a* and b* of color were analyzed in extruded flours. The viscosity related parameters determined include initial viscosity, viscosity peak, breakdown, setback and final viscosity. The results showed effect of feed moisture on flour color (L* and a* and the extrusion temperature influenced b*. Moisture content of the feed had effect on initial and final viscosity, viscosity peak and breakdown. Extrusion temperature and screw speed had effect on final viscosity and setback.

  7. Incidence Proportion of Acute Cor Pulmonale in Patients with Acute Respiratory Distress Syndrome Subjected to Lung Protective Ventilation: A Systematic Review and Meta-analysis.

    Science.gov (United States)

    Das, Saurabh Kumar; Choupoo, Nang Sujali; Saikia, Priyam; Lahkar, Amitabh

    2017-06-01

    Reported incidence of acute cor pulmonale (ACP) in patients with acute respiratory distress syndrome (ARDS) varies from 10% to 84%, despite being subjected to lung protective ventilation according to the current guidelines. The objective of this review is to find pooled cumulative incidence of ACP in patients with ARDS undergoing lung protective ventilation. We searched MEDLINE, EMBASE, Cochrane Library, KoreaMed, LILACS, and WHO Clinical Trial Registry. Cross-sectional or cohort studies were included if they reported or provided data that could be used to calculate the incidence proportion of ACP. Inverse variance heterogeneity (IVhet) and random effect model were used for the main outcome and measures. We included 16 studies encompassing 1661 patients. The cumulative incidence of ACP using IVhet analysis was 23% (95% confidence interval [CI] = 18%-28%) over 3 days of lung protective ventilation. Random effect analysis of 7 studies (1250 patients) revealed pooled odd ratio of mortality of 1.16 (95% CI = 0.80-1.67, P = 0.44) due to ACP. Patients with ARDS have a 23% risk of developing ACP with lung protective ventilation. Findings of this review indicate the need of updating existing guidelines for ventilating ARDS patients to incorporate right ventricle protective strategy.

  8. 76 FR 70110 - Foreign-Trade Zone 109-County of Jefferson, NY; Application for Reorganization and Expansion...

    Science.gov (United States)

    2011-11-10

    ... Coffeen Street, Watertown; and, Site 2 (16 acres)--Dexter Sulphite Mill, 349 Lakeview Dr. & Stockton Avenue, Dexter. The grantee's proposed service area under the ASF would be the County of Jefferson, New..., NYS Route 12F, 22529 Airport Drive, Dexter. The ASF allows for the possible exemption of one magnet...

  9. 76 FR 77728 - Process for a Designated Contract Market or Swap Execution Facility To Make a Swap Available To...

    Science.gov (United States)

    2011-12-14

    ... Mar. 8, 2011 at 2; Letter from Dexter Senft, Morgan Stanley, dated Mar. 2, 2011 at 4; Letter from... from Dexter Senft, Morgan Stanley, dated Mar. 2, 2011 at 4; Letter from Timothy Cameron, Securities... Wayne Pestone, FX Alliance Inc., dated Nov. 4, 2011 at 9-10. \\57\\ Letter from Dexter Senft, Morgan...

  10. COR1 Engineering Test Unit Measurements at the NCAR/HAO Vacuum Tunnel Facility, October-November 2002

    Science.gov (United States)

    Thompson, William

    2002-01-01

    The Engineering Test Unit (ETU) of COR1 was made in two configurations. The first configuration, ETU-1, was for vibration testing, while the second, ETU-2, was for optical testing. This is a report on the optical testing performed on ETU-2 at the NCAR/HAO Vacuum Tunnel Facility during the months of October and November, 2002. This was the same facility used to test the two previous breadboard models. In both configurations, the first two tube sections were complete, with all optical elements aligned. The vibration model ETU-1 had the remaining tube sections attached, with mass models for the remaining optics, for the various mechanisms, and for the focal plane assembly. It was then converted into the optical model ETU-2 by removing tube sections 3 to 5, and mounting the remaining optics on commercial mounts. (The bandpass filter was also installed into tube 2, which had been replaced in ETU-1 by a mass model, so that pre- and post-vibration optical measurements could be made.) Doublet 2 was installed in a Newport LP-2 carrier, and aligned to the other optics in the first two tube sections. The LP-2 adjustment screws were then uralened so that the alignment could be maintained during shipping. Because neither the flight polarizer nor Hollow Core Motor were available, they were simulated by a commercial polarizer and rotational mount, both from Oriel corporation. The Oriel rotational stage was not designed for vacuum use, but it was determined after consultation with the company, and lab testing, that the stage could be used in the moderate vacuum conditions at the NCAR/HAO facility. The shutter and focal plane assembly were simulated with the same camera used for the previous two breadboard tests. The focal plane mask was simulated with a plane of BK7 glass with a mask glued on, using the same procedure as for the Lyot spot on Doublet 1, and mounted in an adjustable LP-2 carrier. Two masks were made, one made to the precise specifications of the optical design, the

  11. Avaliação da cor, corrosão e rugosidade superficial do titânio c.p., ligas metálicas e resina acrílica termopolimerizável sob a ação de soluções higienizadoras

    OpenAIRE

    Letícia Resende Davi

    2010-01-01

    A higienização das próteses parciais ou totais removíveis é fundamental para a durabilidade do tratamento e prevenção de patologias orais. O objetivo deste estudo foi avaliar o efeito de agentes higienizadores de prótese na cor, corrosão e rugosidade superficial do titânio c.p., ligas metálicas e resina acrílica termopolimerizável, simulando um período de 180 dias de higienização. Espécimes em formato de discos (12 mm x 3 mm) foram confeccionados em: titânio comercialmente puro (Tritan - Ti c...

  12. Variação da cor e propriedades cerâmicas com o aumento da temperatura de queima de uma argila proveniente da formação Corumbataí, região de Piracicaba, SP Variation of color and ceramic properties with the increase of temperature of clay's firing from the Corumbataí formation, region of Piracicaba, SP

    Directory of Open Access Journals (Sweden)

    C. D. Roveri

    2007-12-01

    Full Text Available Objetivando compreender a influência do ferro contido na illita, presente na formação Corumbataí, na cor de queima de produtos cerâmicos selecionou-se uma amostra de cor cinza esverdeado claro, dominantemente illítica e com porcentagem de óxidos e hidróxidos de ferro relativamente baixo, com base em estudos petrográficos, mineralógicos e químicos. Para os testes cerâmicos, os corpos de prova foram queimados em forno de queima rápida de laboratório nas temperaturas de 900 ºC, 950 ºC, 1000 ºC, 1050 ºC, 1075 ºC e 1100 ºC, com taxa de aquecimento de 40 ºC/min, sendo um conjunto de corpos de prova queimado a 950 ºC, porém com taxa de aquecimento de 20 ºC/min, com o intuito de verificar a influência do tempo de queima na coloração das peças cerâmicas. O tempo de queima mostrou não interferir significativamente na alteração da cor e os corpos de prova apenas apresentaram alterações significativas a partir da temperatura de 1000 ºC, adquirindo, respectivamente os matizes: laranja, vermelho e marrom escuro. A mudança de cor foi acompanhada em intensidade equivalente pela retração linear de queima, pela absorção de água e módulo de ruptura por flexão.The objective of this paper is to understand the influence of the iron contained in the illite, present in the Corumbataí formation, in the color of firing of ceramic products. A sample was selected, with a gray color clearly, with illite domination, hydroxide and oxide percentage and relatively low iron, with basis of petrographics, mineralogical and chemical studies. For the ceramic essays, the test bodies were fired in a fast firing kiln of laboratory in the temperatures of 900 ºC, 950 ºC, 1000 ºC, 1050 ºC, 1075 ºC and 1100 ºC, with heating rate of 40 ºC/min, a set of bodies test was fired at 950 ºC, however with heating rate of 20 ºC/min, for the checking of the influence of the time of firing range in the coloration of the ceramic plates. The time of

  13. On Chinese National Continuous Operating Reference Station System of GNSS

    Directory of Open Access Journals (Sweden)

    CHEN Junyong

    2007-11-01

    Full Text Available Objective: Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System can maintain a accurate, 3D, geocentric and dynamic reference coordinate frame in the corresponding area, can provide positioning and navigation service. It can also serve for the meteorology, geodynamics, earthquake monitoring and Location Based services (LBS etc in the same area. Until now, our country can’t provide a facing National CORS System serving for every profession and trade, and the national sharing platform of CORS System resources has not been established. So this paper discusses some valuable insight how to construct the National CORS System in China. Method: Constructing goal、Service object、CORS distribution、CORS geographic、geology and communication environment and other factors, are major considerations for the Constructing the National CORS System. Moreover, constructing GNSS CORS is more specific, mainly from four aspects, namely site-selection、civil construction、security measures and equipment-selection for consideration. Outcome: The project of the Constructing Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System in china is put forward, and is discussed from goal、principle、project and other for construction. Some meaning thought how to construct the National CORS System is submitted Conclusion: The Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System in china is the lack of a unified planning and design in the national level. So far, the national CORS system serving all walks of life has not been provided, and the national sharing platform of CORS System resources has not been established The primary mission of the Global navigation satellite system (GNSS Continuous Operating Reference Station (CORS System in china is as follows: using data set of GNSS and receiving, transport, process, integration, transmit information and

  14. Kinematics optimization and static analysis of a modular continuum robot used for minimally invasive surgery.

    Science.gov (United States)

    Qi, Fei; Ju, Feng; Bai, Dong Ming; Chen, Bai

    2018-02-01

    For the outstanding compliance and dexterity of continuum robot, it is increasingly used in minimally invasive surgery. The wide workspace, high dexterity and strong payload capacity are essential to the continuum robot. In this article, we investigate the workspace of a cable-driven continuum robot that we proposed. The influence of section number on the workspace is discussed when robot is operated in narrow environment. Meanwhile, the structural parameters of this continuum robot are optimized to achieve better kinematic performance. Moreover, an indicator based on the dexterous solid angle for evaluating the dexterity of robot is introduced and the distal end dexterity is compared for the three-section continuum robot with different range of variables. Results imply that the wider range of variables achieve the better dexterity. Finally, the static model of robot based on the principle of virtual work is derived to analyze the relationship between the bending shape deformation and the driven force. The simulations and experiments for plane and spatial motions are conducted to validate the feasibility of model, respectively. Results of this article can contribute to the real-time control and movement and can be a design reference for cable-driven continuum robot.

  15. Determinação da cor, imagem superficial topográfica e ângulo de contato de biofilmes de diferentes fontes de amido Determination of color, topographic superficial image and contact angle of the biofilms of different starch sources

    Directory of Open Access Journals (Sweden)

    Washington Azevêdo da Silva

    2007-02-01

    Full Text Available Atualmente, um dos problemas que acometem o meio ambiente é a poluição ocasionada pelo descarte de filmes plásticos de polímeros sintéticos sem nenhum controle. Uma das alternativas para minimizar este problema é a utilização de amido na elaboração de materiais biodegradáveis que possuem alta degradabilidade quando lançados no meio ambiente. Apesar do número crescente de trabalhos de pesquisas utilizando diferentes materiais biodegradáveis, o conhecimento das propriedades físicas de biofilmes elaborados com amido ainda é bastante reduzido. Objetivou-se com este trabalho determinar a diferença de cor, a imagem superficial topográfica por microscopia eletrônica de varredura e o ângulo de contato de biofilmes elaborados com três diferentes tipos de amido: filme de fécula de batata (FFB, filme de fécula de mandioca (FFM e filme de amido de milho (FAM com três concentrações: 1, 2 e 3% empregando-se um delineamento inteiramente casualizado com três repetições. A interação concentração e tipo de amido foi estatisticamente significativa para ângulo de contato e não significativa para a diferença de cor. A diferença de cor foi afetada pela fonte de amido e o maior valor observado para filme de fécula de mandioca. Com o aumento da concentração de amido, o ângulo de contato diminuiu para filmes de fécula de mandioca e de batata, diferentemente para os biofilmes de milho, onde esta relação foi constante.Nowadays, the pollution has considerably increased by the large amount of the non-degradable synthetic plastics that is discarded everyday in the environment. One of the alternatives that could contribute to minimize this problem would be the use of the starch as main composite in biodegradable films also called biofilms; in other words, this material is easily degradable when disposed in the environment. Despite the growing number of the scientific papers there is a lack of knowledge of the physical properties of

  16. Annual National Test and Evaluation Conference (27th) Held in Tampa, Florida on March 14-17, 2011

    Science.gov (United States)

    2011-03-17

    Time, Budget) Is it better to be precisely incorrect or approximately correct? (“Dewey Beats Truman” vs “A President was Elected”) (If the...Arm/Hand Strength Hearing Threshold – High Freq. Right Arm/Hand Strength Binauralism Left Arm/Hand Dexterity Endurance Right Arm/Hand Dexterity...Left Arm/Hand Strength Hearing Threshold – High Freq. Right Arm/Hand Strength Binauralism Left Arm/Hand Dexterity Endurance Right Arm/Hand

  17. Influência das condições de armazenamento sobre os pigmentos cárneos e a cor do salame italiano fatiado Influence the storage conditions on the meats pigments and the color of the sliced italian salame

    Directory of Open Access Journals (Sweden)

    Cristiane Michele Marches

    2006-09-01

    Full Text Available O consumo de produtos cárneos fatiados tem aumentado nos últimos anos, particularmente os produtos curados como o salame. Os vários tipos de salame existentes são fatiados pelas indústrias de carne e/ou pelos supermercados, sem levar em conta as possíveis alterações que possam vir a ocorrer com tal procedimento. As alterações que ocorrem nos pigmentos cárneos totais e nitrosos repercutem na cor, que é detectada pelo consumidor e influencia diretamente no consumo de produtos desta natureza. O presente estudo teve como objetivo investigar o efeito da intensidade de luz, do oxigênio e da temperatura na conversão dos pigmentos cárneos em nitrosos, na quantidade de pigmentos cárneos totais e nitrosos e no índice de cor vermelha, nas fatias de salame tipo italiano. Tais fatias foram acondicionadas em quatro modelos de embalagens diferentes quanto à permeabilidade à luz e ao oxigênio e armazenadas durante 32 dias em temperaturas de 10 °C e 15 °C sob 930 LUX, continuamente, sendo estas condições similares às empregadas em gôndolas de supermercados. A quantidade dos pigmentos cárneos totais e nitrosos, o índice de cor vermelha (a*, determinado pelo método CIE* Lab, foram mensurados nas fatias no zero, 4º, 6º, 12º, 14º, 19º, 25º, 27º e 32º dia de armazenamento. Os resultados obtidos foram avaliados estatisticamente por análise de variância e teste de Tukey, adotando nível de confiança de 95% (p The consumption of sliced meat products has grown in the last few years, especially for cured products as pastrami. The different kinds of pastrami are sliced by meat industry or in the supermarkets, without concern on possible alterations that may occur in the product. The changes on the total and nitrous meat pigments influence the color of the product, which is detected by the consumer, and thus directly influences the consumption of this kind of product. The present study aimed to investigate the effect of light

  18. Effect of light curing tip distance and resin shade on microhardness of a hybrid resin composite Efeito da distância da ponta do aparelho de fotoativação e da cor na microdureza superficial de um compósito híbrido

    Directory of Open Access Journals (Sweden)

    Flávio Henrique Baggio Aguiar

    2005-12-01

    Full Text Available Resin composite shades and resin composite polymerization performed with a distanced light tip are factors that can affect polymerization effectiveness. Thisin vitro study aimed to evaluate the influence of curing tip distance and resin shade on the microhardness of a hybrid resin composite (Z250 - 3M ESPE. Forty-five resin composite specimens were randomly prepared and divided into nine experimental groups (n = 5: three curing tip distances (2 mm, 4 mm, and 8 mm and three resin shades (A1, A3.5, and C2. All samples were polymerized with a continuous output at 550 mW/cm². After 24 hours, Knoop microhardness measurements were obtained on the top and bottom surfaces of the sample, with a load of 25 grams for 10 seconds. Five indentations were performed on each surface of each sample. Results showed that bottom surface samples light-cured at 2 mm and 4 mm presented significantly higher hardness values than samples light-cured at 8 mm. The resin shade A1 presented higher hardness values and was statistically different from C2. The resin shade A3.5 did not present statistical differences from A1 and C2. For the top surface, there were no statistical differences among the curing tip distances. For all experimental conditions, the top surface showed higher hardness values than the bottom surface. It was concluded that light curing tip distance and resin shade are important factors to be considered for obtaining adequate polymerization.A cor do compósito e a polimerização realizada com a ponta do aparelho de fotoativação distante da superfície do compósito são fatores que podem afetar a efetividade de polimerização. Assim, o objetivo deste estudo in vitro foi avaliar a influência desses fatores na microdureza superficial de um compósito híbrido (Z250 - 3M ESPE. Quarenta e cinco espécimes de compósito foram aleatoriamente preparados de acordo com os nove grupos experimentais (n = 5: três distâncias de fotoativação (2 mm, 4 mm e 8 mm e

  19. Improvement in children’s fine motor skills following a computerized typing intervention

    OpenAIRE

    McGlashan, Hannah L.; Blanchard, Caroline C.V.; Sycamore, Nicole J.; Lee, Rachel; French, Blandine; Holmes, Nicholas P.

    2017-01-01

    Children spend a large proportion of their school day engaged in tasks that require manual dexterity. If children experience difficulties with their manual dexterity skills it can have a consequential effect on their academic achievement. The first aim of this paper was to explore whether an online interactive typing intervention could improve children’s scores on a standardised measure of manual dexterity. The second aim was to implement a serial reaction time tapping task as an index of chi...

  20. CARACTERIZAÇÃO COLORIMÉTRICA DAS MADEIRAS DE MUIRAPIRANGA (Brosimum rubescensTaub. E DE SERINGUEIRA (Hevea brasiliensis, clone Tjir 16 Müll Arg. VISANDO À UTILIZAÇÃO EM INTERIORES

    Directory of Open Access Journals (Sweden)

    Cristine da Silva Autran

    2006-09-01

    Full Text Available Ainda que recente, a técnica para a determinação da cor da madeira por meio da colorimetria quantitativa mostra-se precisa e eficaz. O sistema CIELAB 1976, que determina os parâmetros colorimétricos L*, a*, b*, C e h*, mostrou-se eficiente para a determinação da cor das madeiras de muirapiranga (Brosimum rubescens e de seringueira (Hevea brasiliensis, clone Tjir 16. A madeira de muirapiranga é de cor vermelha-amarronzada (L* de 42,39, tendo o pigmento vermelho (a* de 22,02 como determinante, apesar de o pigmento amarelo (b* ter influência significativa na definição de sua cor. A madeira de seringueira apresenta cor amarela (L* de 77,55, fortemente influenciada pelo pigmento amarelo (b* de 19,61. Considerando o parâmetro cor, ambas as madeiras apresentam potenciais para serem utilizadas em interiores.

  1. Anthropomorphic Robot Hand And Teaching Glove

    Science.gov (United States)

    Engler, Charles D., Jr.

    1991-01-01

    Robotic forearm-and-hand assembly manipulates objects by performing wrist and hand motions with nearly human grasping ability and dexterity. Imitates hand motions of human operator who controls robot in real time by programming via exoskeletal "teaching glove". Telemanipulator systems based on this robotic-hand concept useful where humanlike dexterity required. Underwater, high-radiation, vacuum, hot, cold, toxic, or inhospitable environments potential application sites. Particularly suited to assisting astronauts on space station in safely executing unexpected tasks requiring greater dexterity than standard gripper.

  2. 78 FR 65376 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ... remains of one adult female and one child were collected during construction activities near Dexter, MI... landowner discovered the remains of a young adult female on his property located near Dexter, MI, and gave...

  3. Cobalamin analogues in humans

    DEFF Research Database (Denmark)

    Hardlei, Tore Forsingdal; Obeid, Rima; Herrmann, Wolfgang

    2013-01-01

    BACKGROUND: Haptocorrin (HC) carries cobalamin analogues (CorA), but whether CorA are produced in the body is unknown. All cobalamins (Cbl) to the foetus are delivered by the Cbl-specific protein transcobalamin (TC), and therefore analysis of cord serum for CorA may help to clarify the origin...

  4. Transparent Metal-Salt-Filled Polymeric Radiation Shields

    Science.gov (United States)

    Edwards, David; Lennhoff, John; Harris, George

    2003-01-01

    "COR-RA" (colorless atomic oxygen resistant -- radiation shield) is the name of a transparent polymeric material filled with x-ray-absorbing salts of lead, bismuth, cesium, and thorium. COR-RA is suitable for use in shielding personnel against bremsstrahlung radiation from electron-beam welding and industrial and medical x-ray equipment. In comparison with lead-foil and leaded-glass shields that give equivalent protection against x-rays (see table), COR-RA shields are mechanically more durable. COR-RA absorbs not only x-rays but also neutrons and rays without adverse effects on optical or mechanical performance. The formulation of COR-RA with the most favorable mechanical-durability and optical properties contains 22 weight percent of bismuth to absorb x-rays, plus 45 atomic percent hydrogen for shielding against neutrons.

  5. Cervico-ocular Reflex Is Increased in People With Nonspecific Neck Pain.

    Science.gov (United States)

    de Vries, Jurryt; Ischebeck, Britta K; Voogt, Lennard P; Janssen, Malou; Frens, Maarten A; Kleinrensink, Gert-Jan; van der Geest, Jos N

    2016-08-01

    Neck pain is a widespread complaint. People experiencing neck pain often present an altered timing in contraction of cervical muscles. This altered afferent information elicits the cervico-ocular reflex (COR), which stabilizes the eye in response to trunk-to-head movements. The vestibulo-ocular reflex (VOR) elicited by the vestibulum is thought to be unaffected by afferent information from the cervical spine. The aim of the study was to measure the COR and VOR in people with nonspecific neck pain. This study utilized a cross-sectional design in accordance with the STROBE statement. An infrared eye-tracking device was used to record the COR and the VOR while the participant was sitting on a rotating chair in darkness. Eye velocity was calculated by taking the derivative of the horizontal eye position. Parametric statistics were performed. The mean COR gain in the control group (n=30) was 0.26 (SD=0.15) compared with 0.38 (SD=0.16) in the nonspecific neck pain group (n=37). Analyses of covariance were performed to analyze differences in COR and VOR gains, with age and sex as covariates. Analyses of covariance showed a significantly increased COR in participants with neck pain. The VOR between the control group, with a mean VOR of 0.67 (SD=0.17), and the nonspecific neck pain group, with a mean VOR of 0.66 (SD=0.22), was not significantly different. Measuring eye movements while the participant is sitting on a rotating chair in complete darkness is technically complicated. This study suggests that people with nonspecific neck pain have an increased COR. The COR is an objective, nonvoluntary eye reflex and an unaltered VOR. This study shows that an increased COR is not restricted to patients with traumatic neck pain. © 2016 American Physical Therapy Association.

  6. Reliability of Entire Corneal Thickness Mapping in Normal Post-Laser in situ Keratomileusis and Keratoconus Eyes Using Long Scan Depth Spectral Domain Optical Coherence Tomography.

    Science.gov (United States)

    Xu, Zhe; Chen, Sisi; Yang, Chun; Huang, Shenghai; Shen, Meixiao; Wang, Yuanyuan

    2018-01-01

    To investigate the repeatability and reproducibility of mapping the entire corneal thickness using spectral domain optical coherence tomography (SD-OCT). Thirty normal eyes, 30 post-laser in situ keratomileusis (LASIK) surgery eyes, and 30 keratoconus eyes were analyzed. A custom-built long scan depth SD-OCT device was used to obtain entire corneal images. Ten-millimeter-diameter corneal thickness maps were generated by an automated segmentation algorithm. Intraclass correlation coefficients of repeatability (ICC1) and reproducibility (ICC2), and coefficients of repeatability (CoR1) and reproducibility (CoR2), were calculated to quantify the precision and accuracy of corneal pachymetry measurements using the Bland-Altman method. For SD-OCT measurements in healthy subjects, CoR1 and CoR2 were less than 5.00 and 5.53 μm. ICC1 and ICC2 were more than 0.997 and 0.996. For SD-OCT measurements in LASIK patients, CoR1 and CoR2 were less than 5.09 and 5.34 μm. ICC1 and ICC2 were more than 0.997 and 0.996. For SD-OCT measurements in keratoconus patients, CoR1 and CoR2 were less than 11.57 and 10.92 μm. ICC1 and ICC2 were more than 0.995 and 0.996. The measurements of corneal pachymetric mapping by long scan depth SD-OCT can be assessed over the entire corneal area with good repeatability and reproducibility. © 2017 S. Karger AG, Basel.

  7. Advanced Bimanual Manipulation Results from the DEXMART Project

    CERN Document Server

    2012-01-01

    Dexterous and autonomous manipulation is a key technology for the personal and service robots of the future. Advances in Bimanual Manipulation edited by Bruno Siciliano provides the robotics community with the most noticeable results of the four-year European project DEXMART (DEXterous and autonomous dual-arm hand robotic manipulation with sMART sensory-motor skills: A bridge from natural to artificial cognition). The volume covers a host of highly important topics in the field, concerned with modelling and learning of human manipulation skills, algorithms for task planning, human-robot interaction, and grasping, as well as hardware design of dexterous anthropomorphic hands. The results described in this five-chapter collection are believed to pave the way towards the development of robotic systems endowed with dexterous and human-aware dual-arm/hand manipulation skills for objects, operating with a high degree of autonomy in unstructured real-world environments.

  8. Consumo alimentar na gestação e no pós-parto segundo cor da pele no município do Rio de Janeiro Food intake during pregnancy and postpartum according to skin color in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Elisa Maria de Aquino Lacerda

    2007-12-01

    Full Text Available OBJETIVO: Avaliar o consumo alimentar durante a gestação e pós-parto, segundo cor da pele. MÉTODOS: Estudo longitudinal prospectivo que incluiu 467 mulheres entre 15 e 45 anos no período pós-parto, no município do Rio de Janeiro, entre 1999 e 2001. Foi aplicado um questionário de freqüência de consumo de alimentos aos 15 dias pós-parto (consumo referente ao período da gestação e aos seis meses (consumo referente ao período pós-parto. Foi utilizada análise de covariância para analisar diferenças no consumo alimentar, segundo cor da pele, controlada pela escolaridade. RESULTADOS: Durante a gestação, pretas e pardas apresentaram consumo de energia 13,4% e 9,1% (p=0,009 e p=0,028 e consumo de carboidrato 15,1% e 10,5% maior que brancas (p=0,005 e p=0,014, respectivamente. Mulheres pretas e brancas apresentaram consumo energético 34% e 20% acima das recomendações nutricionais, respectivamente (p=0,035. Durante o período pós-parto, as pretas apresentaram consumo de energia 7,7% maior e consumo de lipídios 14,8% maior que as brancas; consumo de ácidos graxos saturados 23,8% maior que brancas (p=0,003 e 13% maior que pardas (p=0,046. A adequação de consumo de lipídios e ácidos graxos saturados foi maior em pretas que em brancas (p=0,024 e p=0,011, respectivamente. CONCLUSÕES: Os resultados mostram ser necessário revisar estratégias de intervenção nutricional no pré-natal e implementar assistência nutricional no pós-parto, para ajustar o consumo alimentar a níveis adequados, considerando as diferenças por cor/raça identificadas.OBJECTIVE: To assess dietary intake during pregnancy and postpartum according to skin color. METHODS: A longitudinal prospective study was carried out comprising 467 postpartum women aged between 15-45 years in the city of Rio de Janeiro, Southeastern Brazil, in 1999-2001. A food frequency questionnaire was administered at two weeks postpartum (intake covering the pregnancy period and at

  9. Ligand Enhanced Upconversion of Near-Infrared Photons with Nanocrystal Light Absorbers

    Science.gov (United States)

    2016-03-04

    As triplet energy transfer from NCs to ligand molecules are based on the Dexter mechanism, the overlap of wave function is important. The inverse...the molecular engineering required to improve this Dexter energy transfer process. For example, perhaps bulky structures that inhibit TTA between

  10. Implement of Shape Memory Alloy Actuators in a Robotic Hand

    Directory of Open Access Journals (Sweden)

    Daniel Amariei

    2006-10-01

    Full Text Available This paper was conceived to present the ideology of utilizing advanced actuators to design and develop innovative, lightweight, powerful, compact, and as much as possible dexterous robotic hands. The key to satisfying these objectives is the use of Shape Memory Alloys (SMAs to power the joints of the robotic hand. The mechanical design of a dexterous robotic hand, which utilizes non-classical types of actuation and information obtained from the study of biological systems, is presented in this paper. The type of robotic hand described in this paper will be utilized for applications requiring low weight, power, compactness, and dexterity.

  11. Tactile Gloves for Autonomous Grasping With the NASA/DARPA Robonaut

    Science.gov (United States)

    Martin, T. B.; Ambrose, R. O.; Diftler, M. A.; Platt, R., Jr.; Butzer, M. J.

    2004-01-01

    Tactile data from rugged gloves are providing the foundation for developing autonomous grasping skills for the NASA/DARPA Robonaut, a dexterous humanoid robot. These custom gloves compliment the human like dexterity available in the Robonaut hands. Multiple versions of the gloves are discussed, showing a progression in using advanced materials and construction techniques to enhance sensitivity and overall sensor coverage. The force data provided by the gloves can be used to improve dexterous, tool and power grasping primitives. Experiments with the latest gloves focus on the use of tools, specifically a power drill used to approximate an astronaut's torque tool.

  12. Effect of temperature and time immersion of stage soaking on color grains of upland rice parboiled cultivars/ Efeito da temperatura e do tempo de imersão da etapa de encharcamento sobre a cor dos grãos de arroz parboilizado de cultivares de terras altas

    Directory of Open Access Journals (Sweden)

    Priscila Zaczuk Bassinelo

    Full Text Available The parboiling is the hydrothermal treatment of paddy before processing. The objective of this study was to evaluate the influence of the temperature and immersion time step of soaking (independent variables on the color of the grain parboiled (dependent variable cultivars of upland rice (BRS Primavera and BRS Sertaneja. A central composite rotational design (DCCR was used, which includes a 22 full factorial, three replicates at the center point and four axial points, making eleven treatments. It was considered for the selection of hydrothermal conditions to be studied, the criterion of water absorption in the age group from 28% - 32%. In extreme conditions of soaking (high temperature and immersion time was observed in general that the grains of parboiled rice had higher color difference for the samples of grains of white rice. Therefore, the use of temperatures below 65 °C during the soaking tend to have grains with milder browning. After parboiling under different conditions of temperature and time of soaking, the change of color (?E* was greater in cv. BRS Sertaneja. It is possible to produce grains with different shades, depending on the conditions used. The choice will depend on the application that is intended or products in wich the rice will be employed.A parboilização consiste no tratamento hidrotérmico do arroz em casca antes do beneficiamento. O objetivo deste estudo foi avaliar a influência das variáveis temperatura e tempo de imersão da etapa de encharcamento sobre a cor dos grãos parboilizados de cultivares de arroz de terras altas (BRS Primavera e BRS Sertaneja. Utilizou-se um delineamento composto central rotacional (DCCR, que inclui um fatorial completo 22, mais três repetições no ponto central e quatro pontos axiais, totalizando onze tratamentos. Considerou-se para seleção das condições hidrotérmicas, o critério de absorção de água na faixa de 28% – 32%. Nas condições extremas do encharcamento (elevada

  13. Con la guía del Corán: crisis y evolución del discurso numismático almohade

    Directory of Open Access Journals (Sweden)

    Peña Martín, Salvador

    2006-12-01

    Full Text Available First, we examine some unregistered Almohad and Post-Almohad coins, and discuss the attribution or reading of some others. As a result a discussion of a hypothesis on Idrīs al-Ma’mūn’s silver coins is offered and some new items are added to the numismatic corpus of Western Islam. This work leads us to a general overview of the Islamic discourse prevailing in Islamic Spain and North Africa after the so-called Almohad revolution. Considering this discourse as a dynamic work in progress, we focus on a number of issues: (1 the Qur’ānic aim of eternal life as a touchstone in the Almohad system of ideas, (2 the issue whether salvation is possible without actual human guides, (3 the evolution from negative to affirmative theology, (4 the ties binding the numismatic discourse and the Almohad and Post-Almohad ruling classes.

    Partimos de un recorrido histórico por acuñaciones almohades o postalmohades que, o bien no han sido registradas, o bien necesitan nuevas lecturas o atribuciones. Ello nos permite ofrecer una hipótesis sobre las monedas de plata acuñadas por Idrīs al-Ma’mūn y añadir algunos registros al corpus numismático del Occidente islámico en la Baja Edad Media. Ese trabajo nos permite, por otro lado, afrontar el discurso islámico dominante que surgió a raíz de la llamada revolución almohade, lo que hacemos centrándonos en varias cuestiones, entre ellas: 1 la densidad del mensaje sobre la vida eterna en las inscripciones almohades, que derivan de la fuente absoluta del Corán; 2 el problema de si es necesaria, de cara a la salvación, la presencia de guías históricos; 3 la evolución de la teología negativa a la afirmativa, y 4 la estrecha relación entre el discurso numismático y las elites almohades y postalmohades.

  14. Improvement in children's fine motor skills following a computerized typing intervention.

    Science.gov (United States)

    McGlashan, Hannah L; Blanchard, Caroline C V; Sycamore, Nicole J; Lee, Rachel; French, Blandine; Holmes, Nicholas P

    2017-12-01

    Children spend a large proportion of their school day engaged in tasks that require manual dexterity. If children experience difficulties with their manual dexterity skills it can have a consequential effect on their academic achievement. The first aim of this paper was to explore whether an online interactive typing intervention could improve children's scores on a standardised measure of manual dexterity. The second aim was to implement a serial reaction time tapping task as an index of children's finger movement learning, and to see whether performance on this task would improve after the intervention. Seventy-eight typically developing children aged between 8 and 10 were tested at their school on the pre-intervention Movement Assessment Battery for Children (2nd edition; MABC-2) and tapping tasks. Twenty-eight of these children volunteered to be randomly allocated to the intervention or control group. Children in the intervention group had a choice of two online games to play at home over a period of four weeks, while the children in the control group were not given these games to play. The intervention and control groups were then re-tested on the MABC-2 manual dexterity and the tapping task. Children in the intervention group significantly improved their manual dexterity scores in the MABC-2 compared to the control group. On average, all children learnt the tapping sequence, however, there were no group differences and no effect of the intervention on the tapping task. These results have important implications for implementing a freely available, easy to administer, fun and interactive intervention to help children improve their manual dexterity skills. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  15. Differences in unilateral chest press muscle activation and kinematics on a stable versus unstable surface while holding one versus two dumbbells

    Science.gov (United States)

    Patterson, Jeffrey M.; Oppenheimer, Nicole E.; Feser, Erin H.

    2015-01-01

    Training the bench press exercise on a traditional flat bench does not induce a level of instability as seen in sport movements and activities of daily living. Twenty participants were recruited to test two forms of instability: using one dumbbell rather than two and lifting on the COR bench compared to a flat bench. Electromyography (EMG) amplitudes of the pectoralis major, middle trapezius, external oblique, and internal oblique were recorded and compared. Differences in range of motion (ROM) were evaluated by measuring an angular representation of the shoulder complex. Four separate conditions of unilateral bench press were tested while lifting on a: flat bench with one dumbbell, flat bench with two dumbbells, COR Bench with one dumbbell, and COR Bench with two dumbbells. The results imply that there are no differences in EMG amplitude or ROM between the COR bench and traditional bench. However, greater ROM was found to be utilized in the single dumbbell condition, both in the COR bench and the flat bench. PMID:26528421

  16. Identifying Knowledge, Skill, and Ability Requirements for Contracting Officer Representatives in Deployed Environments

    Science.gov (United States)

    2015-06-19

    field, able to operate independently (self-tasked) and are able to multitask . 4 CORs comprehend the processes for coordinating, inspecting, and...identified that the numbers could not be broken out and did a search of their old shared drives for any documents from his predecessors but could not... multitask . 9.) They understand the duties and responsibilities set forth in the COR delegation letter and ensure the COR file is documented

  17. Reliability of power profiles measured on NIMO TR1504 (Lambda-X) and effects of lens decentration for single vision, bifocal and multifocal contact lenses.

    Science.gov (United States)

    Kim, Eon; Bakaraju, Ravi C; Ehrmann, Klaus

    2016-01-01

    To evaluate the repeatability of power profiles measured on NIMO TR1504 (Lambda-X, Belgium) and investigate the effects of lens decentration on the power profiles for single vision (SV), bifocal (BF) and multifocal (MF) contact lenses. Accuracy of the sphere power was evaluated using single vision BK-7 calibration glass lenses of six minus and six plus powers. Three SV and four BF/MF contact lenses - three lenses each, were measured five times to calculate the coefficients of repeatability (COR) of the instrument. The COR was computed for each chord position, lens design, prescription power and operator. One lens from each type was measured with a deliberate decentration up to ±0.5mm in 0.1mm steps. For all lenses, the COR varied across different regions of the half-chord position. In general, SV lenses showed lower COR compared to the BF/MF group lenses. There were no noticeable trends of COR between prescription powers for SV and BF/MF lenses. The shape of the power profiles was not affected when lenses were deliberately decentered for all SV and PureVision MF lenses. However, for Acuvue BF lenses, the peak to trough amplitude of the power profiles flattened up to 1.00D. The COR across the half-chord of the optic zone diameter was mostly within clinical relevance except for the central 0.5mm half-chord position. COR were dependent on the lens type, whereby BF/MF group produced higher COR than SV lenses. The effects of deliberate decentration on the shape of power profiles were pronounced for lenses where the profiles had sharp transitions of power. Copyright © 2015 Spanish General Council of Optometry. Published by Elsevier Espana. All rights reserved.

  18. Jasmonate ZIM-domain (JAZ protein regulates host and nonhost pathogen-induced cell death in tomato and Nicotiana benthamiana.

    Directory of Open Access Journals (Sweden)

    Yasuhiro Ishiga

    Full Text Available The nonhost-specific phytotoxin coronatine (COR produced by several pathovars of Pseudomonas syringae functions as a jasmonic acid-isoleucine (JA-Ile mimic and contributes to disease development by suppressing plant defense responses and inducing reactive oxygen species in chloroplast. It has been shown that the F-box protein CORONATINE INSENSITIVE 1 (COI1 is the receptor for COR and JA-Ile. JASMONATE ZIM DOMAIN (JAZ proteins act as negative regulators for JA signaling in Arabidopsis. However, the physiological significance of JAZ proteins in P. syringae disease development and nonhost pathogen-induced hypersensitive response (HR cell death is not completely understood. In this study, we identified JAZ genes from tomato, a host plant for P. syringae pv. tomato DC3000 (Pst DC3000, and examined their expression profiles in response to COR and pathogens. Most JAZ genes were induced by COR treatment or inoculation with COR-producing Pst DC3000, but not by the COR-defective mutant DB29. Tomato SlJAZ2, SlJAZ6 and SlJAZ7 interacted with SlCOI1 in a COR-dependent manner. Using virus-induced gene silencing (VIGS, we demonstrated that SlJAZ2, SlJAZ6 and SlJAZ7 have no effect on COR-induced chlorosis in tomato and Nicotiana benthamiana. However, SlJAZ2-, SlJAZ6- and SlJAZ7-silenced tomato plants showed enhanced disease-associated cell death to Pst DC3000. Furthermore, we found delayed HR cell death in response to the nonhost pathogen Pst T1 or a pathogen-associated molecular pattern (PAMP, INF1, in SlJAZ2- and SlJAZ6-silenced N. benthamiana. These results suggest that tomato JAZ proteins regulate the progression of cell death during host and nonhost interactions.

  19. Coronatine Facilitates Pseudomonas syringae Infection of Arabidopsis Leaves at Night

    Science.gov (United States)

    Panchal, Shweta; Roy, Debanjana; Chitrakar, Reejana; Price, Lenore; Breitbach, Zachary S.; Armstrong, Daniel W.; Melotto, Maeli

    2016-01-01

    In many land plants, the stomatal pore opens during the day and closes during the night. Thus, periods of darkness could be effective in decreasing pathogen penetration into leaves through stomata, the primary sites for infection by many pathogens. Pseudomonas syringae pv. tomato (Pst) DC3000 produces coronatine (COR) and opens stomata, raising an intriguing question as to whether this is a virulence strategy to facilitate bacterial infection at night. In fact, we found that (a) biological concentration of COR is effective in opening dark-closed stomata of Arabidopsis thaliana leaves, (b) the COR defective mutant Pst DC3118 is less effective in infecting Arabidopsis in the dark than under light and this difference in infection is reduced with the wild type bacterium Pst DC3000, and (c) cma, a COR biosynthesis gene, is induced only when the bacterium is in contact with the leaf surface independent of the light conditions. These findings suggest that Pst DC3000 activates virulence factors at the pre-invasive phase of its life cycle to infect plants even when environmental conditions (such as darkness) favor stomatal immunity. This functional attribute of COR may provide epidemiological advantages for COR-producing bacteria on the leaf surface. PMID:27446113

  20. Coronatine Facilitates Pseudomonas syringae Infection of Arabidopsis Leaves at Night.

    Science.gov (United States)

    Panchal, Shweta; Roy, Debanjana; Chitrakar, Reejana; Price, Lenore; Breitbach, Zachary S; Armstrong, Daniel W; Melotto, Maeli

    2016-01-01

    In many land plants, the stomatal pore opens during the day and closes during the night. Thus, periods of darkness could be effective in decreasing pathogen penetration into leaves through stomata, the primary sites for infection by many pathogens. Pseudomonas syringae pv. tomato (Pst) DC3000 produces coronatine (COR) and opens stomata, raising an intriguing question as to whether this is a virulence strategy to facilitate bacterial infection at night. In fact, we found that (a) biological concentration of COR is effective in opening dark-closed stomata of Arabidopsis thaliana leaves, (b) the COR defective mutant Pst DC3118 is less effective in infecting Arabidopsis in the dark than under light and this difference in infection is reduced with the wild type bacterium Pst DC3000, and (c) cma, a COR biosynthesis gene, is induced only when the bacterium is in contact with the leaf surface independent of the light conditions. These findings suggest that Pst DC3000 activates virulence factors at the pre-invasive phase of its life cycle to infect plants even when environmental conditions (such as darkness) favor stomatal immunity. This functional attribute of COR may provide epidemiological advantages for COR-producing bacteria on the leaf surface.

  1. Dos imaginários sobre a iniciação sexual: intersecções de gênero, raça/cor e sexualidade entre jovens de camadas populares em Belém, Pará

    Directory of Open Access Journals (Sweden)

    Ramon Reis

    Full Text Available Resumo Este texto propõe uma exposição sobre o “roteiro sexual” de mulheres e homens jovens (heterossexuais e homossexuais residentes em regiões “centrais” e “periféricas” da capital paraense, tendo como base material oriundo do projeto “‘Para entrar no mundo que não é meu’: a iniciação sexual a partir de entrevistas com as(os jovens pobres e de camadas médias de Belém do Pará”. Neste sentido, concentramos nossas incursões na Casa do Estudante Universitário do Pará (CEUP, localizada no bairro de classe média/média alta Batista Campos, e no bairro Guamá - “periferia” de Belém. Enfatizamos, assim, o importante papel das famílias de origem na reprodução de práticas de conduta social e sexual, além das distintas maneiras de as(os entrevistadas(os agenciarem suas iniciações sexuais a partir de convenções e imaginários acionados na interseção com gênero, sexualidade e raça/cor.

  2. Estimation of the center of rotation using wearable magneto-inertial sensors.

    Science.gov (United States)

    Crabolu, M; Pani, D; Raffo, L; Cereatti, A

    2016-12-08

    Determining the center of rotation (CoR) of joints is fundamental to the field of human movement analysis. CoR can be determined using a magneto-inertial measurement unit (MIMU) using a functional approach requiring a calibration exercise. We systematically investigated the influence of different experimental conditions that can affect precision and accuracy while estimating the CoR, such as (a) angular joint velocity, (b) distance between the MIMU and the CoR, (c) type of the joint motion implemented, (d) amplitude of the angular range of motion, (e) model of the MIMU used for data recording, (f) amplitude of additive noise on inertial signals, and (g) amplitude of the errors in the MIMU orientation. The evaluation process was articulated at three levels: assessment through experiments using a mechanical device, mathematical simulation, and an analytical propagation model of the noise. The results reveal that joint angular velocity significantly impacted CoR identification, and hence, slow joint movement should be avoided. An accurate estimation of the MIMU orientation is also fundamental for accurately subtracting the contribution owing to gravity to obtain the coordinate acceleration. The unit should be preferably attached close to the CoR, but both type and range of motion do not appear to be critical. When the proposed methodology is correctly implemented, error in the CoR estimates is expected to be <3mm (best estimates=2±0.5mm). The findings of the present study foster the need to further investigate this methodology for application in human subjects. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Ozonização em meio básico para redução de cor do licor negro de indústria de celulose de algodão Color reduction of black liquor from cotton cellulose industry using ozonation in an alkaline medium

    Directory of Open Access Journals (Sweden)

    José Roberto Guimarães

    2010-03-01

    Full Text Available As indústrias de papel e celulose descartam no ambiente um grande volume de efluente contendo grande quantidade da substância lignina, que atribui coloração e apresenta considerável potencial de toxicidade. Neste trabalho, foi avaliada a ozonização em meio básico para a redução de cor do licor negro gerado por uma indústria de celulose de algodão. Face aos resultados, foi possível observar que, para menores concentrações iniciais de ozônio (0,4 gO3 L-1 h-1, foi necessário um tempo mais longo de ozonização para se obter a redução desejada de 80% da cor. O consumo específico de ozônio, entretanto, em comparação a experimentos com dosagens mais elevadas (4,3 gO3 L-1 h-1 foi menor. Sugere-se que o oxigênio molecular desempenhe, também, um importante papel na oxidação dos compostos, participando do mecanismo de oxidação iniciado por radical hidroxila, •OH, formado na ozonização em meio básico.Pulp and paper mills discharge large amounts of wastewater containing high concentrations of lignin, a coloring substance that is dangerous and presents high toxicity to the environment. In this study, ozonation in alkaline ambience was evaluated for color reduction in black liquor, generated in a cotton linter mill. It was observed that the ozonation time to reach 80% color reduction was higher at a lower initial ozone dose (0,4 gO3 L-1 h-1 in comparison to a higher initial ozone dose (4,3 gO3 L-1 h-1. On the other hand, the amount of consumed oxidant was lower at the lower ozone dose. It is suggested that molecular oxygen participates in the oxidation mechanism of colored compounds, which is initiated by hydroxyl radicals (•OH formed during ozonation in alkaline ambience.

  4. Changes in gross grasp strength and fine motor skills in adolescents with pediatric multiple sclerosis.

    Science.gov (United States)

    Squillace, Mary; Ray, Sharon; Milazzo, Maria

    2015-01-01

    This study examined the gross grasp strength and fine motor dexterity of adolescents, who are diagnosed with multiple sclerosis (MS). A total sample size of 72 participants between the ages of 13 to 17 was studied. Thirty six with a diagnosis of pediatric relapse remitting MS and 36 matched control participants were selected from various local youth groups. Data on hand strength and dexterity was collected using a dynamometer, nine hole peg board and Purdue pegboard on both groups. Utilizing ANCOVA to describe the differences across the two groups by diagnosis, controlling for age and gender, it was found that the MS group demonstrated significantly decreased dexterity when compared to age and gender matched controls. There was no significant difference in gross grasp strength by diagnostic group. This preliminary study showed that children with a diagnosis of pediatric MS may have differences in fine motor dexterity, but not gross grasp strength from their peers who do not have the diagnosis. Further study is indicated to examine this phenomenon.

  5. Can Coronene and/or Benzo(a)pyrene/Coronene ratio act as unique markers for vehicle emission?

    International Nuclear Information System (INIS)

    Shen, Guofeng; Chen, Yuanchen; Wei, Siye; Fu, Xiaofang; Ding, Aijun; Wu, Haisuo; Tao, Shu

    2014-01-01

    Coronene is a high molecular weight polycyclic aromatic hydrocarbon with seven aromatic rings. It, more specifically a lower ratio of Benzo[a]pyrene to Coronone (BaP/COR), is suggested as a marker for vehicle emission. In the present study, emissions of Coronene were measured from residential combustions of wood, crop straw, and pellets. The detection of COR in non-vehicle emission sources, and comparable BaP/COR ratios between the solid fuel combustion and vehicle emissions indicated that the generality of COR or the BaP/COR ratio as markers for the vehicle emission would be questionable, especially for the area where solid fuel combustion dominated the PAHs emission. Highlights: • Coronene alone is not a unique marker for vehicle emission. • The specific ratio, BaP/Coronene, could be very high for gasoline emission. • The use of a specific ratio, BaP/Coronene, as a marker is debatable. -- Coronene alone is not a unique tracer for vehicle emission and the use of specific Benzo[a]pyrene to Coronene ratio needs more evaluation studies

  6. Assessment of Protective Gloves for Use with Airfed Suits.

    Science.gov (United States)

    Millard, Claire E; Vaughan, Nicholas P

    2015-10-01

    Gloves are often needed for hand protection at work, but they can impair manual dexterity, especially if they are multilayered or ill-fitting. This article describes two studies of gloves to be worn with airfed suits (AFS) for nuclear decommissioning or containment level 4 (CL4) microbiological work. Both sets of workers wear multiple layers of gloves for protection and to accommodate decontamination procedures. Nuclear workers are also often required to wear cut-resistant gloves as an extra layer of protection. A total of 15 subjects volunteered to take part in manual dexterity testing of the different gloving systems. The subjects' hands were measured to ensure that the appropriate sized gloves were used. The gloves were tested with the subjects wearing the complete clothing ensembles appropriate to the work, using a combination of standard dexterity tests: the nine-hole peg test; a pin test adapted from the European Standard for protective gloves, the Purdue Pegboard test, and the Minnesota turning test. Specialized tests such as a hand tool test were used to test nuclear gloves, and laboratory-type manipulation tasks were used to test CL4 gloves. Subjective assessments of temperature sensation and skin wettedness were made before and after the dexterity tests of the nuclear gloves only. During all assessments, we made observations and questioned the subjects about ergonomic issues related to the clothing ensembles. Overall, the results show that the greater the thickness of the gloves and the number of layers the more the levels of manual dexterity performance are degraded. The nuclear cut-resistant gloves with the worst level of dexterity were stiff and inflexible and the subjects experienced problems picking up small items and bending their hands. The work also highlighted other factors that affect manual dexterity performance, including proper sizing, interactions with the other garments worn at the time, and the work equipment in use. In conclusion, when

  7. Significance of determination of insulin, glucagon and cortisol levels in maternal and umbilical cord blood

    International Nuclear Information System (INIS)

    Li Chun; Li Runhao; Yan Songqin

    2006-01-01

    Objective: To determine the insulin (INS), glucagon (GLUC) and cortisol (COR) levels in maternal and umbilical cord blood for appropriate gestational age (AGA) neonates and to explore the correlation among the body weight of AGA neonates and body mass index (BMI) of pregnant woman, serum INS, GLUC, COR levels of maternal as well as umbilical cord blood. Methods: Neonates fell into lower-than-normal body weight group ( group A n=9) and higher-than-normal body weight group (group B n =17); serum INS, GLUC and COR levels were measured with radioimmunoassay in 26 pairs of mothers and neonates with uneventful delivery. Results: The body weight of neonate was positively correlated with the BMI of pregnant women, the BMI of pregnant women in group B were significantly higher than those in group A (P<0.05). The maternal serum GLUC and COR levels were significantly higher than those in cord blood (P<0.05, P<0.01). Cord blood COR contents in group B were significantly higher than those in group A (P<0.01), the reverse was true for GLUC (P<0.05). Conclusion: Fetal growth is closely related to the BMI of pregnant women and serum INS, GLUC and COR levels indicating that maternal nutritional condition would directly affect the birth weight of the neonates. (authors)

  8. The Tanaka-Johnston orthodontic analysis for brazilian individuals = Efetividade da análise ortodôntica de Tanaka e Johnston em brasileiros

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    Vilella, Oswaldo de Vasconcellos

    2012-01-01

    Conclusão: A análise de Tanaka e Johnston permite uma predição aceitável do somatório dos diâmetros mésio-distais dos caninos e pré-molares dos indivíduos brasileiros de cor de pele negra e de cor de pele branca do gênero masculino. Com relação aos indivíduos de cor de pele branca do gênero feminino, os valores foram superestimados

  9. Hector Field, Fargo North Dakota. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    Science.gov (United States)

    1987-12-01

    HOLRS I TSTMS C/OR RAIN L/OR HAIL WITH FOG C/OR uLO6ING C/OR A/LBST TOIAL ULT) I ORIZILL C/OP SLEET PRECIP PAZE SNOb SAND 10 0bC I RZZLE VIS ION JA. LE...AISARTEITItS TO t MILES ANT) GREATER THAN L rALT S. T1-.LBOPE TI J-L LOEUMN FOB BICIbILI TIES F,;ijAL T0 OR GREATER THAN 1D MALLS APPEAl BLANK. AS A "EL

  10. Antidepressant-Like Effects of Cordycepin in a Mice Model of Chronic Unpredictable Mild Stress

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    Zhang Tianzhu

    2014-01-01

    Full Text Available Cordycepin (3′-deoxyadenosine, a major bioactive component isolated from Cordyceps militaris, has multiple pharmacological activities. This study is attempted to investigate whether cordycepin (COR possesses beneficial effects on chronic unpredictable mild stress- (CUMS- induced behavioral deficits (depression-like behaviors and explore the possible mechanisms. ICR mice were subjected to chronic unpredictable mild stress for 42 consecutive days. Then, COR and fluoxetine (FLU, positive control drug were administered for 21 consecutive days at the last three weeks of CUMS procedure. The classical behavioral tests, open field test (OFT, sucrose preference test (SPT, tail suspension test (TST, and forced swimming test (FST, were applied to evaluate the antidepressant effects of COR. Then the serotonin (5-HT and noradrenaline (NE concentrations in hippocampal were evaluated by HPLC; tumor necrosis factor-α (TNF-α and interleukin-6 (IL-6 in hippocampal were evaluated, and the proteins of TNF-α, IL-6, NF-κBP65 5-HT receptor (5-HTR, and brain-derived neurotrophic factor (BDNF in hippocampal were evaluated by Western blot. Our results indicated that 6 weeks of CUMS exposure induced significant depression-like behavior, with low 5-HT and NE levels, high TNF-α and IL-6 in brain and high hippocampal TNF-α, IL-6, P-NF-κBP65, and 5-HTR levels, and low BDNF expression levels. Whereas, chronic COR (20, 40 mg/kg treatments reversed the behavioral deficiency induced by CUMS exposure, treatment with COR normalized the change of TNF-α, IL-6, 5-HT, and NE levels, which demonstrated that COR could partially restore CUMS-induced 5-HT receptor impairments and inflammation. Besides, hippocampal BDNF expressions were also upregulated after COR treatments. In conclusion, COR remarkably improved depression-like behavior in CUMS mice and its antidepressant activity is mediated, at least in part, by the upregulating BDNF and downregulating 5-HTR levels and

  11. Sexo e cor: categorias de controle social e reprodução das desigualdades socioeconômicas no brasil Sex and aolor skin: categories of social aontrol and reproduction of economic inequality in brazil

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    Waldemir Rosa

    2009-12-01

    Full Text Available O presente artigo objetiva apresentar algumas reflexões sobre os dados contidos no Retrato das Desigualdades de Gênero e Raça, terceira edição, acerca das desigualdades socioeconômicas e da pobreza. Tendo como linha argumentativa a tese de que, como categorias de controle social, sexo e cor configuram marcos reguladores de oportunidades sociais, apresentamos alguns dados sobre a desigualdade entre homens e mulheres e entre negros e brancos que ilustram as iniquidades de poder associadas a essa desigualdade. Ressalta-se que tais categorias são fundamentais para a compreensão da produção e da reprodução das iniquidades de poder que permeiam a sociedade brasileiraThis article presents some reflections on the data contained in the Portrait of Inequalities of Gender and Race - 3rd Edition on socioeconomic inequalities and poverty. Following a line of argument that, as categories of social control, gender and ethnicity shape regulatory frameworks of social opportunities, we present some data on inequality between men and women and between blacks and whites that illustrate the inequities of power associated with them. It is emphasized that these categories are fundamental to understand the production and reproduction of inequities of power that permeate Brazilian society

  12. Central Pressure Appraisal: Clinical Validation of a Subject-Specific Mathematical Model.

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    Francesco Tosello

    Full Text Available Current evidence suggests that aortic blood pressure has a superior prognostic value with respect to brachial pressure for cardiovascular events, but direct measurement is not feasible in daily clinical practice.The aim of the present study is the clinical validation of a multiscale mathematical model for non-invasive appraisal of central blood pressure from subject-specific characteristics.A total of 51 young male were selected for the present study. Aortic systolic and diastolic pressure were estimated with a mathematical model and were compared to the most-used non-invasive validated technique (SphygmoCor device, AtCor Medical, Australia. SphygmoCor was calibrated through diastolic and systolic brachial pressure obtained with a sphygmomanometer, while model inputs consist of brachial pressure, height, weight, age, left-ventricular end-systolic and end-diastolic volumes, and data from a pulse wave velocity study.Model-estimated systolic and diastolic central blood pressures resulted to be significantly related to SphygmoCor-assessed central systolic (r = 0.65 p <0.0001 and diastolic (r = 0.84 p<0.0001 blood pressures. The model showed a significant overestimation of systolic pressure (+7.8 (-2.2;14 mmHg, p = 0.0003 and a significant underestimation of diastolic values (-3.2 (-7.5;1.6, p = 0.004, which imply a significant overestimation of central pulse pressure. Interestingly, model prediction errors mirror the mean errors reported in large meta-analysis characterizing the use of the SphygmoCor when non-invasive calibration is performed.In conclusion, multi-scale mathematical model predictions result to be significantly related to SphygmoCor ones. Model-predicted systolic and diastolic aortic pressure resulted in difference of less than 10 mmHg in the 51% and 84% of the subjects, respectively, when compared with SphygmoCor-obtained pressures.

  13. Coronary calcium visualization using dual energy chest radiography with sliding organ registration

    Science.gov (United States)

    Wen, Di; Nye, Katelyn; Zhou, Bo; Gilkeson, Robert C.; Wilson, David L.

    2016-03-01

    Coronary artery calcification (CAC) is the lead biomarker for atherosclerotic heart disease. We are developing a new technique to image CAC using ubiquitously ordered, low cost, low radiation dual energy (DE) chest radiography (using the two-shot GE Revolution XRd system). In this paper, we proposed a novel image processing method (CorCalDx) based on sliding organ registration to create a bone-image-like, coronary calcium image (CCI) that significantly reduces motion artifacts and improves CAC conspicuity. Experiments on images of a physical dynamic cardiac phantom showed that CorCalDx reduced 73% of the motion artifact area as compared to standard DE over a range of heart rates up to 90 bpm and varying x-ray radiation exposures. Residual motion artifact in the phantom CCI is greatly suppressed in gray level and area (0.88% of the heart area). In a Functional Measurement Test (FMT) with 20 clinical exams, image quality improvement of CorCalDx against standard DE (measured from -10 to +10) was significantly suggested (panatomy visibility (6.1+/-3.5). CorCalDx was always chosen best in every image tested. In preliminary assessments of 12 patients with 18 calcifications, 90% of motion artifact regions in standard DE results were removed in CorCalDx results, with 100% sensitivity of calcification detection, showing great potential of CorCalDx to improve CAC detection and grading in DE chest radiography.

  14. Ultrastructural alterations of choroid plexuses of lateral ventricles of rats (Rattus norvegicus submitted to experimental chronic alcoholism Alterações ultraestruturais dos plexos coróides dos ventrículos laterais de ratos (Rattus norvegicus submetidos a alcoolismo crônico experimental

    Directory of Open Access Journals (Sweden)

    LUÍS FERNANDO TIRAPELLI

    2000-03-01

    Full Text Available Adult male rats (Wistar lineage were alcoholized with sugar cane liquor diluted at 30(0 GL during 300 days and sacrificed every 60 days in 5 stages. Samples of choroid plexuses of lateral ventricles were collected and examined at transmission electronic microscope to detect possible ultrastructural alterations and to raise possible pathological correlations. Gradual changes were observed in these animals during all the experiment: dilatation and enlargement of cisternae of Golgi complex, dilatation of RER, presence of digestive vacuoles and a large amount of pinocytic vesicles as well as vesicles with electronlucent content throughout cytoplasm, as well as an enlargement of intercellular space between basolateral interdigitation of the cells and of the connective tissue. The changes observed in the epithelium and connective tissue of choroid plexuses specially in 240 and 300 days of treatment are presumably due to a disturbance in hydroelectrolitic homeostasis, contributing to several morpho-functional disturbs of central nervous system. No changes were observed in the control group animals.Ratos machos adultos (linhagem Wistar foram alcoolizados com aguardente de cana diluída a 30(0 GL durante 300 dias e sacrificados a cada 60 dias em 5 etapas. Amostras dos plexos coróides dos ventrículos laterais foram coletadas e examinadas ao microscópio eletrônico de transmissão para detectar possíveis alterações ultraestruturais e suas correlações patológicas. Alterações graduais foram observadas nestes animais durante todo o experimento: dilatação e aumento das cisternas de complexo de Golgi, dilatação do retículo endoplasmático rugoso, presença de vacúolos digestivos e grande quantidade de vesículas pinocíticas assim como de vesículas de conteúdo elétron-lúcido por todo o citoplasma, além de aumento do espaço intercelular, entre as interdigitações das células assim como no tecido conjuntivo. As alterações observadas no

  15. Health-related lifestyle behaviors among male and female rural-to-urban migrant workers in Shanghai, China.

    Science.gov (United States)

    Yang, Hua; He, Fang; Wang, Tianhao; Liu, Yao; Shen, Yao; Gong, Jian; Dai, Wei; Zhou, Jing; Gu, Jie; Tu, Yimin; Wang, Tianying; Shen, Lei; Wu, Yumiao; Xia, Xiuping; Xu, Donghao; Pan, Zhigang; Zhu, Shanzhu

    2015-01-01

    Lifestyle behaviors significantly impact health, yet remain poorly defined in Chinese rural-to-urban migrants. In a cross-sectional study of health-related behaviors of 5484 rural-to-urban migrants who had worked in Shanghai for at least six months, we assessed the contribution of demographics and physical and mental health to lifestyle behaviors in male and female participants by multiple stepwise cumulative odds logistic regression. Respondents were 51.3% male. 9.9% exhibited abnormal blood pressure; 27.0% were overweight or obese; 11.2% reported abnormal mental health; 36.9% reported healthy lifestyle. Multiple stepwise cumulative odds logistic regression indicated that men working in manufacturing reported less unhealthy lifestyle than those in hospitality (cumulative odds ratio (COR) = 1.806, 95%CI 1.275-2.559) or recreation/leisure (COR = 3.248, 95%CI 2.379-4.435); and women working in manufacturing and construction reported less unhealthy lifestyle than those in all other sectors. Unhealthy lifestyle was associated with small workplaces for men (COR = 1.422, 95%CI 1.154-1.752), working more than 8 or 11 hours per day for women and men, respectively, and earning over 3500 RMB in women (COR = 1.618, 95%CI 1.137-2.303). Single women and women who had previously resided in three or more cities were more likely to report unhealthy lifestyle (COR = 2.023, 95%CI 1.664-2.461, and COR = 1.311, 95%CI 1.072-1.602, respectively). Abnormal mental status was also correlated with unhealthy lifestyle in men (COR = 3.105, 95%CI 2.454-3.930) and women (COR = 2.566, 95%CI 2.024-3.252). There were different risk factors of unhealthy lifestyle score in male and female rural-to-urban migrants, especially in number of cities experienced, salary, marital status, work place scale. Several demographic groups: employment sectors (e.g. hospitality and recreation/leisure), working conditions (e.g. long hours) and abnormal mental status were associated with unhealthy lifestyle behaviors

  16. Health-related lifestyle behaviors among male and female rural-to-urban migrant workers in Shanghai, China.

    Directory of Open Access Journals (Sweden)

    Hua Yang

    Full Text Available Lifestyle behaviors significantly impact health, yet remain poorly defined in Chinese rural-to-urban migrants.In a cross-sectional study of health-related behaviors of 5484 rural-to-urban migrants who had worked in Shanghai for at least six months, we assessed the contribution of demographics and physical and mental health to lifestyle behaviors in male and female participants by multiple stepwise cumulative odds logistic regression.Respondents were 51.3% male. 9.9% exhibited abnormal blood pressure; 27.0% were overweight or obese; 11.2% reported abnormal mental health; 36.9% reported healthy lifestyle. Multiple stepwise cumulative odds logistic regression indicated that men working in manufacturing reported less unhealthy lifestyle than those in hospitality (cumulative odds ratio (COR = 1.806, 95%CI 1.275-2.559 or recreation/leisure (COR = 3.248, 95%CI 2.379-4.435; and women working in manufacturing and construction reported less unhealthy lifestyle than those in all other sectors. Unhealthy lifestyle was associated with small workplaces for men (COR = 1.422, 95%CI 1.154-1.752, working more than 8 or 11 hours per day for women and men, respectively, and earning over 3500 RMB in women (COR = 1.618, 95%CI 1.137-2.303. Single women and women who had previously resided in three or more cities were more likely to report unhealthy lifestyle (COR = 2.023, 95%CI 1.664-2.461, and COR = 1.311, 95%CI 1.072-1.602, respectively. Abnormal mental status was also correlated with unhealthy lifestyle in men (COR = 3.105, 95%CI 2.454-3.930 and women (COR = 2.566, 95%CI 2.024-3.252.There were different risk factors of unhealthy lifestyle score in male and female rural-to-urban migrants, especially in number of cities experienced, salary, marital status, work place scale. Several demographic groups: employment sectors (e.g. hospitality and recreation/leisure, working conditions (e.g. long hours and abnormal mental status were associated with unhealthy lifestyle

  17. Sustitución de lardo por grasa vegetal en salchichas: incorporación de pasta de aguacate. Efecto de la inhibición del oscurecimiento enzimático sobre el color Substituição do toucinho por gordura vegetal em salsichas: adição da pasta de abacate. Efeito da inibição do escurecimiento enzimatico na cor

    Directory of Open Access Journals (Sweden)

    Ubaldo Rueda-Lugo

    2006-06-01

    Full Text Available La sustitución de grasa animal es importante para mejorar la calidad nutricional de los alimentos de origen animal. Tradicionalmente, los embutidos contienen cantidades relativamente altas de grasas insaturadas, por lo que se ha buscado la sustitución parcial o total de estas con grasas o aceites de origen vegetal. El aprovechamiento del aguacate como fuente de grasa vegetal es una alternativa para este tipo de productos. La oxidación de este fruto es uno de los principales problemas durante la industrialización. En este trabajo se han añadido dos inhibidores del oscurecimiento enzimático, ácido ascórbico y eritorbato de sodio, para determinar el efecto de éstos sobre el color de salchichas de cerdo. Se han encontrado diferencias en la luminosidad de las muestras con respecto al tratamiento control, además de que este mismo parámetro se ha reducido con el tiempo de almacenamiento. No ha habido efecto significativo de los antioxidantes sobre las otras componentes del color. El uso de eritorbato de sodio en la elaboración de pasta de aguacate ha reducido el oscurecimiento de la pasta durante su congelación, sin afectar mayormente otros parámetros de color del producto terminado. La aceptación del producto por un grupo de consumidores ha sido aceptable.A substituição da gordura animal ou toucinho é importante para melhorar a qualidade nutricional dos alimentos de origem animal. Tradicionalmente, os embutidos contêm quantidades relativamente elevadas de gorduras insaturadas, e a substituição parcial ou total com gordura vegetal ou óleo é desejável. O abacate é fonte de gordura vegetal como uma alternativa para este tipo de produto. A oxidação desta fruta é um dos problemas principais durante a industrialização. Neste trabalho foram adicionados dois inibidores de escurecimento enzimatico, ácido ascórbico e eritorbato do sódio, para determinar o efeito destes na cor das salsichas. As diferenças na luminosidade das

  18. Bonum vinum laetificat cor hominum.

    Science.gov (United States)

    Stoclet, J C

    2001-01-01

    Beneficial effects of wine consumption on health have been suspected since the antiquity. Recent epidemiological studies show that coronary heart disease mortality markedly decreases from northern to southern Europe and is lower in Mediterranean than in other developed countries. Because wine is a component of the Mediterranean diet, it has been suggested that moderate wine especially red wine consumption may produce additional beneficial effects on cardiovascular morbidity and mortality compared to consuming the same quantity of alcohol in other beverages. Polyphenols are good candidates to explain the putative cardiovascular protective effect of wine, because they are abundant in wine especially red wine, and possess antioxidant and superoxide ion scavenging properties. Because it is readily accessible from blood and produces cardioprotective agents like nitric oxide (NO) the endothelial cell may be a privileged target for wine polyphenols. Polyphenols from red wine can prevent oxidation of low density lipoproteins (LDL). As oxidized LDL inhibit agonist-activated NO release from endothelial cells and subsequent endothelium-dependent relaxation of arteries, wine polyphenols might prevent LDL-induced alterations of endothelial function. Furthermore some wine polyphenols contained in oligomeric condensed tannins- and anthocyaninsD enriched fractions can act directly on endothelial cells to cause calcium-dependent release of NO. The latter effect is independent from superoxide scavenging and antioxidant properties of the polyphenols, and it is produced by compounds with specific structures only. Thus, decreased oxidation of LDL and enhanced release of NO from endothelium caused by polyphenols from red wine may result in cardiovascular protection. However further studies are required to demonstrate whether or not these effects are involved in the putative protective effect of wine on cardiovascular morbidity and mortality.

  19. The effect of acute exercise and psychosocial stress on fine motor skills and testosterone concentration in the saliva of high school students.

    Directory of Open Access Journals (Sweden)

    Mirko Wegner

    Full Text Available Little is known about the influence of different stressors on fine motor skills, the concentration of testosterone (T, and their interaction in adolescents. Therefore, 62 high school students aged 14-15 years were randomly assigned to two experimental groups (exercise, psychosocial stress and a control group. Exercise stress was induced at 65-75% of the maximum heart rate by running for 15 minutes (n = 24. Psychosocial stress was generated by an intelligence test (HAWIK-IV, which was uncontrollable and characterized by social-evaluative-threat to the students (n = 21. The control group followed was part of a regular school lesson with the same duration (n = 28. Saliva was collected after a normal school lesson (pre-test as well as after the intervention/control period (post-test and was analyzed for testosterone. Fine motor skills were assessed pre- and post-intervention using a manual dexterity test (Flower Trail from the Movement Assessment Battery for Children-2. A repeated measure ANCOVA including gender as a covariate revealed a significant group by test interaction, indicating an increase in manual dexterity only for the psychosocial stress group. Correlation analysis of all students shows that the change of testosterone from pre- to post-test was directly linked (r = -.31, p = .01 to the changes in manual dexterity performance. Participants showing high increases in testosterone from pre- to post-test made fewer mistakes in the fine motor skills task. Findings suggest that manual dexterity increases when psychosocial stress is induced and that improvement of manual dexterity performance corresponds with the increase of testosterone.

  20. Functioning and disability in adults with myotonic dystrophy type 1.

    Science.gov (United States)

    Kierkegaard, Marie; Harms-Ringdahl, Karin; Holmqvist, Lotta Widén; Tollbäck, Anna

    2011-01-01

     To provide a comprehensive description of functioning and disability with regard to stages of disease progression in adults with myotonic dystrophy type 1 (DM1). Further to explore associations of measures of manual dexterity and of walking capacity with measures of activities of daily living (ADL) and participation in social and lifestyle activities. Seventy persons with DM1 underwent examinations, tests and answered questionnaires. Stages of disease progression were based on the muscular impairment rating scale.  Overweight, cardiac dysfunctions, respiratory restrictions, fatigue and/or low physical activity levels were found in approximately 40% of those with DM1. Over 75% had muscle impairments, and activity limitations in manual dexterity and walking. Dependence in personal and instrumental ADL was found in 16% and 39%, respectively, and participation restrictions in social and lifestyle activities in 52%. The presence of concurrent body-function impairments, activity limitations and participation restrictions was high. Significant differences were found in muscle impairment, manual dexterity, mobility, ADL and social and lifestyle activities with regard to disease progression. Cut-off values in measures of manual dexterity and walking capacity associated to functioning are proposed.  This information can be used for developing clinical practise and for health promotion for persons with DM1.

  1. Design and control of five fingered under-actuated robotic hand

    Science.gov (United States)

    Sahoo, Biswojit; Parida, Pramod Kumar

    2018-04-01

    Now a day's research regarding humanoid robots and its application in different fields (industry, household, rehabilitation and exploratory) is going on entire the globe. Among which a challenging topic is to design a dexterous robotic hand which not only can perform as a hand of a robot but also can be used in re habilitation. The basic key concern is a dexterous robot hand which can be able to mimic the function of biological hand to perform different operations. This thesis work is regarding design and control of a under-actuated robotic hand consisting of four under actuated fingers (index finger, middle finger, little finger and ring finger ) , a thumb and a dexterous palm which can copy the motions and grasp type of human hand which having 21degrees of freedom instead of 25Degree Of Freedom.

  2. Next-generation robotic surgery--from the aspect of surgical robots developed by industry.

    Science.gov (United States)

    Nakadate, Ryu; Arata, Jumpei; Hashizume, Makoto

    2015-02-01

    At present, much of the research conducted worldwide focuses on extending the ability of surgical robots. One approach is to extend robotic dexterity. For instance, accessibility and dexterity of the surgical instruments remains the largest issue for reduced port surgery such as single port surgery or natural orifice surgery. To solve this problem, a great deal of research is currently conducted in the field of robotics. Enhancing the surgeon's perception is an approach that uses advanced sensor technology. The real-time data acquired through the robotic system combined with the data stored in the robot (such as the robot's location) provide a major advantage. This paper aims at introducing state-of-the-art products and pre-market products in this technological advancement, namely the robotic challenge in extending dexterity and hopefully providing the path to robotic surgery in the near future.

  3. Functionalized Cobalt Triarylcorrole Covalently Bonded with Graphene Oxide: A Selective Catalyst for the Two- or Four-Electron Reduction of Oxygen.

    Science.gov (United States)

    Tang, Jijun; Ou, Zhongping; Guo, Rui; Fang, Yuanyuan; Huang, Dong; Zhang, Jing; Zhang, Jiaoxia; Guo, Song; McFarland, Frederick M; Kadish, Karl M

    2017-08-07

    A cobalt triphenylcorrole (CorCo) was covalently bonded to graphene oxide (GO), and the resulting product, represented as GO-CorCo, was characterized by UV-vis, FT-IR, and micro-Raman spectroscopy as well as by HRTEM, TGA, XRD, XPS, and AFM. The electrocatalytic activity of GO-CorCo toward the oxygen reduction reaction (ORR) was then examined in air-saturated 0.1 M KOH and 0.5 M H 2 SO 4 solutions by cyclic voltammetry and linear sweep voltammetry using a rotating disk electrode and/or a rotating ring-disk electrode. An overall 4-electron reduction of O 2 is obtained in alkaline media while under acidic conditions a 2-electron process is seen. The ORR results thus indicate that covalently bonded GO-CoCor can be used as a selective catalyst for either the 2- or 4-electron reduction of oxygen, the prevailing reaction depending upon the acidity of the solution.

  4. Cosmic Origins Program Annual Technology Report

    Science.gov (United States)

    Pham, Bruce Thai; Neff, Susan Gale

    2015-01-01

    What is the Cosmic Origins (COR) Program? From ancient times, humans have looked up at the night sky and wondered: Are we alone? How did the universe come to be? How does the universe work? COR focuses on the second question. Scientists investigating this broad theme seek to understand the origin and evolution of the universe from the Big Bang to the present day, determining how the expanding universe grew into a grand cosmic web of dark matter enmeshed with galaxies and pristine gas, forming, merging, and evolving over time. COR also seeks to understand how stars and planets form from clouds in these galaxies to create the heavy elements that are essential to life starting with the first generation of stars to seed the universe, and continuing through the birth and eventual death of all subsequent generations of stars. The COR Programs purview includes the majority of the field known as astronomy, from antiquity to the present.

  5. Program Annual Technology Report: Cosmic Origins Program Office

    Science.gov (United States)

    Pham, Thai; Neff, Susan

    2017-01-01

    What is the Cosmic Origins (COR) Program? From ancient times, humans have looked up at the night sky and wondered: Are we alone? How did the universe come to be? How does the universe work? COR focuses on the second question. Scientists investigating this broad theme seek to understand the origin and evolution of the universe from the Big Bang to the present day, determining how the expanding universe grew into a grand cosmic web of dark matter enmeshed with galaxies and pristine gas, forming, merging, and evolving over time. COR also seeks to understand how stars and planets form from clouds in these galaxies to create the heavy elements that are essential to life, starting with the first generation of stars to seed the universe, and continuing through the birth and eventual death of all subsequent generations of stars. The COR Programs purview includes the majority of the field known as astronomy.

  6. TRATAMENTOS ALTERNATIVOS DO EFLUENTE DE UMA INDÚSTRIA DE CELULOSE BRANQUEADA E PAPEL

    Directory of Open Access Journals (Sweden)

    Celso Edmundo Bochetti Foelkel

    1998-12-01

    Full Text Available Este trabalho procurou avaliar a eficiência de tratamento floculante com sulfato de alumínio ou cloreto férrico para o efluente bruto neutralizado de uma indústria de celulose e papel. A filtração do efluente, removendo fibras, finos, macromoléculas e flocos naturais, permitiu expressivas reduções da cor aparente, cor real e DQO do mesmo. Enquanto o sulfato de alumínio mostrou excelentes resultados, o cloreto férrico não teve bom desempenho. Deve-se otimizar as concentrações, as formas de agitação e a decantação dos flocos. Para as amostras testadas, na primeira seqüência de testes, concentrações com cerca de 2500 ppm de sulfato de alumínio (com 14 moléculas de água de hidratação mostraram ótimos resultados para redução de cor aparente, cor real, DQO e cloretos. Conforme o previsto, na segunda seqüência de testes as concentrações de [Al2(SO43 . 14 H2O] diminuíram para todos os índices físico-químicos testados. A melhor concentração para pH, cor aparente e cor real foi de 1000 ppm filtrado, enquanto que para cloretos foi de 2000 ppm não filtrado, com o tempo de agitação de 1 minuto com alta velocidade e 15 minutos à baixa velocidade, com exceção da cor real que foi de 10 minutos à baixa velocidade. Como recomendação, sugere-se avaliar uma etapa seqüencial de filtração após clarifloculação/decantação. Com isso, o desempenho de um tratamento físico-químico de efluentes desse tipo será eficiente, apesar do custo envolvido na aquisição do insumo sulfato de alumínio.

  7. CAMBIOS DE COLOR Y PERFIL AROMÁTICO EN SOLUCIONES OSMÓTICAS USADAS EN DESHIDRATACIÓN OSMÓTICA DE TOMATE DE ÁRBOL COR E SABOR MUDANÇAS NO SOLUÇÃO OSMÓTICA, UTILIZADO NA DESIDRATAÇÃO OSMÓTICA DE TOMATE DE ÁRVORE COLOR AND FLAVOR CHANGES ON THE OSMOTIC SOLUTION, USED IN THE OSMOTIC DEHYDRATION OF TREE TOMATO

    Directory of Open Access Journals (Sweden)

    Magda Ivonne Pinzón

    2011-12-01

    alimenticios. Neste trabalho avaliar as alterações do perfil de cor e aroma do SO, uma vez que é reutilizada em 9 ciclos fazer considerando que estas duas propriedades terão grande influência sobre as características sensoriais nos de novos produtos concebidos. Cubos de tomate de árvore deformadas foram utilizados, seca por 240 minutos em 65° Brix OS com uma solução Ratio:fruto de 5:1. Em cada ciclo de DO, foram renovadas as frutas e reutilizando o SO sem reorientação, esforçando a cada 4 ciclos de 9 ciclos de DO. Ele analisa a cor dos encontrando assim uma tendencia descendente em L* no SO e outras alterações em outros parâmetros da cor: a*,b*,C* e h° que só foram valorizados instrumentalmente, essas mudanças de cor SO não demonstraram um efeito drástico sobre a cor das frutas desidratado, além de encontrar o aparecimento de componentes de aroma de tomate na árvore OS como era reutilizado.The reusing of the osmotic solution (OS in the osmotic dehydration (OD process of tropical fruits, enriched with exotic flavors like the tree tomatoes (Cyphomadra betecea (Cav Sendth, from which very satisfactory results have been obtained, changes the different properties of the OS. The most important one being the enrichment in different sustains that came from the fruit; this makes the OS a very interesting raw matter in the formulation and desing of new food products. In this paper we study the changes in the color and flavor of the OS when being reused, taking into account that these properties will have a bigger impact in the sensatory properties of the new food product. Deformed tree tomatoes cubes were used, dehydrate during 240 minutes, using a 65°Brix OS, with a fruit:solution rate of 5:1. In each OD cycle fresh fruit was used and the same OS, without re-concentration, filtrating every four cycles during 9 OD cycles. The color of the OS was analyzed finding a descent in the L* values and changes in the other color parameters: a*, b* C*, h°, that were only

  8. WATER SPRAY-CHILLING OF BEEF CARCASSES AND MEAT AGEING ON WEIGHT LOSS, COLOR AND LONGISSIMUS LUMBORUM ACCEPTANCE ASPERSÃO DE ÁGUA FRIA NO INÍCIO DO RESFRIAMENTO DE CARCAÇAS BOVINAS E MATURAÇÃO DA CARNE SOBRE O PESO, COR E ACEITAÇÃO DO MÚSCULO LONGISSIMUS LUMBORUM

    Directory of Open Access Journals (Sweden)

    PEDRO EDUARDO DE FELÍCIO

    2007-12-01

    Full Text Available

    The objective of this experiment was to evaluate the effects of spray-chilling in carcasses weight loss, purge loss, color and appearance of aged striploin (m. Longissi-mus lumborum steaks. Two lots of intact male, nearly 12 month old, grain finished cattle, were slaughtered, being 16 of the Montana composite breed, in the first slaughter, and 24 crossbreds (½ Nelore X ½ Simental in the second one. After bleeding, electrical stimulation, skinning and evisceration, the carcasses submitted to one of the two cooling systems: (1 Without spray-chilling (SA; (2 With spray-chilling (CA. Carcasses were weighted before and after cooling. In the boning room steaks of 2.5 cm thick from the striploin were taken, vacuum packaged, and aged for 7, 14, 30 and 60 days. Samples were then removed from the package, placed in an expanded polystyrene trays covered with a PVC film, and exposed in refrigerated displays for 48 hours. CIE Lab color was measured after 24 hours using a hand colorimeter. A visual analysis of the samples was also done for the attributes of color, overall acceptability, and buying option. The spray-chilling was efficient in reducing the weight loss (P<0.05. Effects (P<0.001 of the spray-chilling and aging time on purge loss were observed. The samples from the CA carcasses had higher (P<0.001 purge loss, which had an increase at 30 or more days of aging in this treatment but not in the SA. No effect (P>0.05 of the spray-chilling treatment and aging time was observed on the color visual analysis.

    Key-words:  Beef quality purge loss,  spray-chilling, striploin, vacuum package.

    O objetivo desta pesquisa foi avaliar os efeitos da aspersão de água gelada, nas primeiras seis horas de resfriamento, nas perdas de peso por evaporação das carcaças e, também, do tempo de maturação em embalagem a vácuo, nas perdas por exsudação da carne, e na cor e aceita

  9. Violência, etnia e cor: um estudo dos diferenciais na região metropolitana de Salvador, Bahia, Brasil Violence, ethnic group, and skin color: a study of disparities in the metropolitan region of Salvador, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Ceci Vilar Noronha

    1999-04-01

    Full Text Available O objetivo do presente estudo é analisar a distribuição das distintas modalidades de violência - estrutural, institucional, interpessoal e derivada da delinqüência - nos três grupos de cor mais representativos da sociedade baiana: brancos, mulatos e negros. O estudo compara os níveis de vitimação de indivíduos brancos, negros e mulatos com suas próprias avaliações da eficiência das instituições de controle do crime, procurando identificar como isso se relaciona com a adoção de atitudes e normas autoritárias pelos mesmos sujeitos. Os dados analisados são provenientes do Estudo Multicêntrico sobre Atitudes e Normas Culturais face à Violência (projeto ACTIVA e compreendem uma amostra de 1384 pessoas residentes na região metropolitana de Salvador. A investigação foi desenhada como um estudo de corte transversal, com entrevistas realizadas nos domicílios, no período de setembro a dezembro de 1996. A seleção da amostra se processou em três etapas: primeiro foram selecionadas, de modo aleatório, as áreas residenciais, seguindo uma amostragem sistemática dos domicílios em cada área do sorteio; por fim, o sujeito a ser entrevistado foi escolhido, também por sorteio. Para a coleta de dados foi utilizado o questionário desenhado para o estudo ACTIVA e testado em estudo piloto. Os resultados indicam uma distribuição desigual da violência estrutural que recai, principalmente, sobre indivíduos de pele negra; o perfil por grupos de cor para a violência interpessoal e institucional revelou-se indistinto. A violência da delinqüência atinge os brancos e os negros na mesma intensidade. O descrédito na eficiência das polícias civil e militar, da justiça e do sistema carcerário é muito alto e é generalizado para os três grupos de cor. Além disso, poucas diferenças foram encontradas entre os grupos com relação a atitudes e normas autoritárias. Com base nos resultados, é possível concluir que existe risco

  10. Parallel hole collimator acceptance tests for SPECT and planar studies

    International Nuclear Information System (INIS)

    Babicheva, R.R.; Bennie, D.N.; Collins, L.T.; Gruenwald, S.M.

    1998-01-01

    Full text: Different kinds of collimator damage can occur either during shipping or from regular use. Imperfections of construction along the strips or their connections give rise to nonperpendicular hole alignments to the crystal face and can produce potential problems such as ring artifacts and image degradation. Gamma camera collimator hole alignments and integrity were compared in four parallel hole high resolution collimators-two new cast and two used foil collimators, one with damage to the protective surface. [1] The point source flood image of the defective collimator was non-circular as were the images of cast collimators. The image of new foil collimator was circular. [2] High count sheet flood did not show any imperfections. [3] Bone mineral densitometer was used to perform collimated X-ray beam. The collimator was placed on the scanning bed with an X-ray cassette placed directly above it. The damaged area was well demonstrated. [4] The COR offset test was taken at two extreme radii. The offset value with the defective collimator is increased by 0.53 pixel or 129% with increase of COR from radius 14 cm to 28cm. [5] The collimator hole alignment test involves performing multiple measurements of COR along the length of the collimator, and checking for variations in COR with both position of source and angle of rotation. The maximum variation in COR of the defective collimator hole alignment was 1.13 mm. Collimators require testing when new and at regular intervals, or following damage. The point source test can be used for foil collimators. The most sensitive tests were collimated X-ray source, COR offset test and collimator hole alignment

  11. Adresse inconnue / Address unknown / Suchwiin Bulmyeong

    OpenAIRE

    Serge Gruzinski

    2005-01-01

    Tous les films asiatiques parlent de métissage, même ceux qui se présentent comme de vastes fresques historiques perdues dans le temps. Les emprunts aux traditions hollywoodiennes et européennes n'ont cessé d'enrichir une cinématographie aussi ancienne que celle du monde occidental. Dans Adresse inconnue (Address unknown) le cinéaste coréen Kim Ki-duk explore l'expérience du métissage et le corps du métis à la frontière entre Corée du Nord et Corée du sud. Fils d'un GI américain et noir et d'...

  12. Atmospheric Effects on Radio Frequency (RF) Wave Propagation in a Humid, Near-Surface Environment

    Science.gov (United States)

    2010-03-01

    additional IR temperature and Campbell water temperature probes, as well as a 3-D sonic anemometer, pyranometer , and LI-COR open path gas analyzer for...Zonen CNR-1 pyranometer . Lastly, the Campbell sonic anemometer (CSAT3) and LI- COR (CS7500) were extended 2.5 meters over the water from an

  13. Curriculum Online Review System: Proposing Curriculum with Collaboration

    Science.gov (United States)

    Rhinehart, Marilyn; Barlow, Rhonda; Shafer, Stu; Hassur, Debby

    2009-01-01

    The Curriculum Online Review System (CORS) at Johnson County Community College (JCCC) uses SharePoint as a Web platform for the JCCC Curriculum Proposals Process. The CORS application manages proposals throughout the approval process using collaboration tools and workflows to notify all stakeholders. This innovative new program has changed the way…

  14. Modeling and control of an anthropomorphic robotic hand

    OpenAIRE

    Bensalah, Choukri

    2016-01-01

    Mención Europea en el título de doctor This thesis presents methods and tools for enabling the successful use of robotic hands. For highly dexterous and/or anthropomorphic robotic hands, these methods have to share some common goals, such as overcoming the potential complexity of the mechanical design and the ability of performing accurate tasks with low and efficient computational cost. A prerequisite for dexterity is to increase the workspace of the robotic hand. For th...

  15. Developments and Control of Biocompatible Conducting Polymer for Intracorporeal Continuum Robots.

    Science.gov (United States)

    Chikhaoui, Mohamed Taha; Benouhiba, Amine; Rougeot, Patrick; Rabenorosoa, Kanty; Ouisse, Morvan; Andreff, Nicolas

    2018-04-30

    Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concentric tube robot paradigm. In the form of tri-layer thin structures, CP micro-actuators produce high strains while requiring less than 1 V for actuation. Fabrication, characterization, and first integrations of such micro-actuators are presented. The integration is validated in a preliminary telescopic soft robot prototype with qualitative and quantitative performance assessment of accurate position control for trajectory tracking scenarios. Further, CP micro-actuators are integrated to a laser steering system in a closed-loop control scheme with displacements up to 5 mm. Our first developments aim toward intracorporeal medical robotics, with miniaturized actuators to be embedded into continuum robots.

  16. Hiina tehaste kurb saatus / Dexter Roberts

    Index Scriptorium Estoniae

    Roberts, Dexter

    2008-01-01

    Hiina tootmisettevõtted on tootmiskulude hüppelise kasvu tõttu läbi elamas restruktureerimisfaasi, mille tagajärjel on mitmed ettevõtted sunnitud oma tootmise viima madalama tootmiskuluga piirkondadesse, tootmismahte suurendama efektiivsuse tõstmise ja kaadrivoolavuse peatamise kaudu või tegevuse lõpetama. Tabel: Tootmiskulude hüppeline kasv Hiinas. Lisa: Viited. Vt. samas: Keskklass pihtide vahel

  17. Tactile Sensing for Dexterous Robotic Hands

    Science.gov (United States)

    Martin, Toby B.

    2000-01-01

    Robotic systems will be used as precursors to human exploration to explore the solar system and expand our knowledge of planetary surfaces. Robotic systems will also be used to build habitats and infrastructure required for human presence in space and on other planetary surfaces . Such robots will require a high level of intelligence and automation. The ability to flexibly manipulate their physical environment is one characteristic that makes humans so effective at these building and exploring tasks . The development of a generic autonomous grasp ing capability will greatly enhance the efficiency and ability of robotics to build, maintain and explore. To tele-operate a robot over vast distances of space, with long communication delays, has proven to be troublesome. Having an autonomous grasping capability that can react in real-time to disturbances or adapt to generic objects, without operator intervention, will reduce the probability of mishandled tools and samples and reduce the number of re-grasp attempts due to dropping. One aspect that separates humans from machines is a rich sensor set. We have the ability to feel objects and respond to forces and textures. The development of touch or tactile sensors for use on a robot that emulates human skin and nerves is the basis for this discussion. We will discuss the use of new piezo-electric and resistive materials that have emerged on the market with the intention of developing a touch sensitive sensor. With viable tacti le sensors we will be one step closer to developing an autonomous grasping capability.

  18. Study on functional relationships between ergonomics indexes of manual performance

    Science.gov (United States)

    Hu, Hui-Min; Ding, Li; Chen, Shou-Ping; Yang, Chun-Xin; Yuan, Xiu-Gan

    This paper investigates functional relationships between some of the key ergonomics indexes in manual performance, and attempts to condense the ergonomics appraisal indexes system and thus evaluate hand performance wearing EVA (extravehicular activity) glove, design and improve EVA glove's performance. Four types of ergonomics indexes were studied, i.e., dexterity, tactile sensibility (TS), strength and fatigue. Two test items of insert sticks into a holes-board (ISIHB) and nuts-bolts assembly task (NBAT) were used to measure dexterity, while shape discrimination (SD) was employed for TS, and grip force (GF) for strength and fatigue. The variables measured in this investigation included accomplishing time (AT) of ISIHB and NBAT, correct rate (CR) of SD, maximal grip force (MGF), instant grip force (IGF) and endurance time of grip force (ETGF). Experiments were conducted on 31 undergraduates (eight female and 23 male) with two experiment conditions of bare-hand group and gloved hand group. Results demonstrated that dexterity and TS performance of gloved hand group declined significantly compared with those of bare-hand group (pfatigue between two conditions (p>0.05). Four effective functional relationships were developed between four pairs of ergonomics indexes in bare-hand group. In gloved hand group, in addition to above-mentioned four pairs of relationships, another formula was found, which was y^=0.02061+0.01233x ( p<0.01, dexterity and TS).

  19. The effect of caffeine ingestion on functional performance in older adults.

    Science.gov (United States)

    Duncan, M J; Clarke, N D; Tallis, J; Guimarães-Ferreira, L; Leddington Wright, S

    2014-12-01

    Caffeine is a widely used nutritional supplement which has been shown to enhance both physical and cognitive performance in younger adults. However, few studies have assessed the effect of caffeine ingestion on performance, particularly functional performance in older adults. The present study aims to assess the effect of acute caffeine ingestion on functional performance, manual dexterity and readiness to invest effort in older adults. 19 apparently healthy, volunteers (10 females and 9 males aged 61-79; 66 ± 2 years) performed tests of functional fitness and manual dexterity post ingestion of caffeine (3mg*kg-1) or placebo in a randomised order. Pre and 60 minutes post ingestion, participants also completed measures of readiness to invest physical (RTIPE) and mental (RTIME) effort. A series of repeated measures ANOVAS indicated enhanced performance in the following functional fitness tests; arm curls (P = .04), 8 foot up and go (P = .007), six minute walk (P = .016). Manual dexterity was also improved in the presence of caffeine (P = .001). RTIME increased (P = .015) pre to post ingestion in the caffeine condition but not in the placebo condition. There were no significant main effects or interactions for RTIPE or gender in any analysis (all P > .05). The results of this study suggest that acute caffeine ingestion positively enhances functional performance, manual dexterity and readiness to invest effort in apparently healthy older adults.

  20. Atividade da catalase e da lactato desidrogenase em tilápias submetidas a estresse de confinamento: efeito da cor do ambiente Catalase and lactate dehydrogenase activity in tilapia subjected to contention stress: effect of the background color

    Directory of Open Access Journals (Sweden)

    Elyara Maria Pereira-da-Silva

    2012-05-01

    Full Text Available Avaliaram-se os efeitos da cor do ambiente sobre o crescimento e a atividade da enzima antioxidante catalase (CAT e da lactato desidrogenase (LDH em tilápias do Nilo (n=24; 36,2±3,6g. Oito exemplares foram mortos para determinação da atividade basal das enzimas e os demais permaneceram isolados durante 14 dias sob espectro de luz branca ou azul (n=8 peixes/tratamento. A seguir os peixes foram submetidos a um estresse diário de confinamento de 90 minutos (15° ao 28° dia e pesados semanalmente para cálculo da taxa de crescimento específico (TCE. A TCE negativa confirmou que o confinamento provocou estresse nos peixes, independentemente da cor do ambiente. O aumento da atividade da LDH no músculo vermelho dos peixes mantidos sob luz branca ou azul indicou mudança do metabolismo aeróbio para anaeróbio. O estresse reduziu a atividade da CAT no músculo branco dos peixes mantidos sob a luz branca ou azul. Na musculatura vermelha, esta redução ocorreu apenas nos animais mantidos sob a luz branca. O confinamento aumenta os processos metabólicos anaeróbios e é adequado para estudos sobre os efeitos do estresse. O espectro de luz azul não evita a redução do crescimento e a demanda energética anaeróbia em situações de estresse, mas preserva a atividade da CAT, contribuindo para o bem-estar da tilápia.We assess the effects of the background color on the growth and antioxidant enzyme catalase (CAT and lactate dehydrogenase (LDH in Nile tilapia (n=24; 36.2±3.6g. Eight fish were killed for assessment of basal activity of the enzymes and the others remained isolated for 14 days under white or blue light spectrum (n=8 fish/treatment. Then each animal were subjected to a daily stress of confinement of 90 minutes (15th to 28th day and weighed to calculate the specific growth rate (SGR. The negative SGR confirmed that the confinement stressed in fish, regardless of the background color. The increased activity of LDH in red muscle of fish

  1. Adresse inconnue / Address unknown / Suchwiin Bulmyeong

    Directory of Open Access Journals (Sweden)

    Serge Gruzinski

    2005-03-01

    Full Text Available Tous les films asiatiques parlent de métissage, même ceux qui se présentent comme de vastes fresques historiques perdues dans le temps. Les emprunts aux traditions hollywoodiennes et européennes n'ont cessé d'enrichir une cinématographie aussi ancienne que celle du monde occidental. Dans Adresse inconnue (Address unknown le cinéaste coréen Kim Ki-duk explore l'expérience du métissage et le corps du métis à la frontière entre Corée du Nord et Corée du sud. Fils d'un GI américain et noir et d...

  2. Uso de simulações na determinação de cores intrínsecas de estrelas no infravermelho

    Science.gov (United States)

    Rembold, S. B.; Ribeiro, D.; Ducati, J. R.; Bevilacqua, C.

    2003-08-01

    Apresentamos o método e alguns resultados preliminares da aplicação de simulações na determinação das cores intrínsecas de estrelas no infravermelho. A simulação consiste em gerar diagramas cor versus temperatura efetiva de estrelas sinteticas, para uma faixa de valores iniciais da cor intrínseca para cada tipo espectral. Os diagramas gerados sinteticamente são comparados com diagramas gerados a partir de observacoes e, com isso, extrai-se a cor intrínseca que melhor descreve as observações. Mostramos tabelas preliminares de cores intrínsecas e comparamos seu comportamento com determinações prévias e de outros autores.

  3. Considerações sobre o dilema entre cor/raça/mestiçagem e ações afirmativas no Brasil / Consideration on the dilemma between color/race/miscegenation and affirmative action in Brazil

    Directory of Open Access Journals (Sweden)

    Mozart Linhares da Silva

    2010-01-01

    Full Text Available O artigo problematiza as abordagens racialistas e não-racialistas que marcam o debate sobre ações afirmativas no Brasil tomando a miscigenação como eixo norteador de ambas as posturas político-teóricas. Propõe uma crítica às abordagens que visam a racialização das identidades no país bem como às abordagens dos intelectuais que, em nome das idiossincrasias locais ou mesmo dos princípios igualitaristas, procuram contornar as políticas diferencialistas. É na tensão entre as políticas de redistribuição e reconhecimento que o texto assenta, portanto, a análise sobre os dilemas entre cor/raça/mestiçagem e políticas de ações afirmativas no Brasil.Abstract The article discusses the racialists and non-racialist approaches that mark the debate on affirmative action’s in Brazil taking miscegenation as a guideline for both political andtheoretical stances. It proposes a critique of the approaches to the racialization of the identities in the country as well as the approaches of the intellectuals who, on behalf of local idiosyncrasies or even egalitarian principles, try to avent differential policies. It is the tension between the redistribution and recognition policies that the text is based on, therefore, the analysis of the dilemmas between color/race/miscegenation and affirmative action policies in Brazil.

  4. An Analysis of Army Contract Administration With Regard to Contracting Officers Representatives

    Science.gov (United States)

    2016-09-01

    TO CONTRACTING OFFICER’S REPRESENTATIVES September 2016 By: Tanya V. Peel Angel R. Acevedo Advisors : Karen Landale Matthew Kremer...among contracting personnel and CORs requires improvement, staff levels need to be increased to support contract administration, managers nominate CORs...Landale, Lead Advisor Matthew Kremer, Support Advisor Brad Naegle Academic Associate Graduate School of Business and Public

  5. Mechanical design of a shape memory alloy actuated prosthetic hand.

    Science.gov (United States)

    De Laurentis, Kathryn J; Mavroidis, Constantinos

    2002-01-01

    This paper presents the mechanical design for a new five fingered, twenty degree-of-freedom dexterous hand patterned after human anatomy and actuated by Shape Memory Alloy artificial muscles. Two experimental prototypes of a finger, one fabricated by traditional means and another fabricated by rapid prototyping techniques, are described and used to evaluate the design. An important aspect of the Rapid Prototype technique used here is that this multi-articulated hand will be fabricated in one step, without requiring assembly, while maintaining its desired mobility. The use of Shape Memory Alloy actuators combined with the rapid fabrication of the non-assembly type hand, reduce considerably its weight and fabrication time. Therefore, the focus of this paper is the mechanical design of a dexterous hand that combines Rapid Prototype techniques and smart actuators. The type of robotic hand described in this paper can be utilized for applications requiring low weight, compactness, and dexterity such as prosthetic devices, space and planetary exploration.

  6. Effect of cold conditions on manual performance while wearing petroleum industry protective clothing.

    Science.gov (United States)

    Wiggen, Øystein Nordrum; Heen, Sigri; Færevik, Hilde; Reinertsen, Randi Eidsmo

    2011-01-01

    The purpose of this study was to investigate manual performance and thermal responses during low work intensity in persons wearing standard protective clothing in the petroleum industry when they were exposed to a range of temperatures (5, -5, -15 and -25℃) that are relevant to environmental conditions for petroleum industry personnel in northern regions. Twelve men participated in the study. Protective clothing was adjusted for the given cold exposure according to current practices. The subjects performed manual tests five times under each environmental condition. The manual performance test battery consisted of four different tests: tactile sensation (Semmes-Weinstein monofilaments), finger dexterity (Purdue Pegboard), hand dexterity (Complete Minnesota dexterity test) and grip strength (grip dynamometer). We found that exposure to -5℃ or colder lowered skin and body temperatures and reduced manual performance during low work intensity. In conclusion the current protective clothing at a given cold exposure is not adequate to maintain manual performance and thermal balance for petroleum workers in the high north.

  7. Intravitreal ranibizumab and bevacizumab for the treatment of nonsubfoveal choroidal neovascularization in age-related macular degeneration Ranibizumab e bevacizumab intravítreo no tratamento da neovascularização de coróide extrafoveal da degeneração macular relacionada à idade

    Directory of Open Access Journals (Sweden)

    Aaron Brock Roller

    2009-10-01

    : The use of intravitreal anti-VEGF agents for nonsubfoveal CNV in AMD is effective. Our results are comparable to published results from large-scale trials of anti-VEGF therapy for subfoveal CNV. Our data support the idea that bevacizumab or ranibizumab appear to be the treatment of choice for AMD patients with nonsubfoveal CNV.OBJETIVO: Investigar a eficácia dos anti-angiogênicos ranibizumab e bevacizumab injetados intravítreo, no tratamento de pacientes com neovascularização de coróide extrafoveal em degeneração macular relacionada à idade. MÉTODOS: Foram avaliados 13 pacientes com neovascularização de coróide extrafoveal em degeneração macular relacionada à idade do Setor de Retina e Vítreo do Departamento de Oftalmologia da Universidade de Iowa, Estados Unidos, que foram tratados por meio de injeção vítrea de ranibizumab e bevacizumab separadamente, em um período de dois anos. Após as injeções iniciais os pacientes foram acompanhados por exames de OCT e as injeções foram repetidas com 4 a 8 semanas dependendo da presença de líquido sub-retiniano e macular. RESULTADOS: Doze pacientes tiveram ganhos de linhas de visão se comparados com a visão antes do tratamento. Onze pacientes tiveram redução do espessamento retiniano na área envolvida pelo CNV e diminuição e resolução do espessamento macular na sua visita final de avaliação. Um paciente (8% perdeu uma linha de visão se comparado à visão prévia ao tratamento. Pacientes tratados com o ranibizumab tiveram em média 2,5 ± 0,7 ganhos de linhas de visão. Pacientes tratados com bevacizumab tiveram em média 1,6 ± ganhos de linhas de visão. CONCLUSÃO: No tratamento de pacientes com a neovascularização de coróide extrafoveal em degeneração macular relacionada à idade, a injeção vítrea de ranibizumab ou bevacizumab é efetiva e pode ser a opção de escolha.

  8. Use of colour parameters for roasted coffee assessment Utilização dos parâmetros de cor para avaliação do café torrado

    Directory of Open Access Journals (Sweden)

    Natalina Cavaco Bicho

    2012-09-01

    Full Text Available Fast and non-destructive indicators were evaluated as tools to measure the technological quality of Arabica and Robusta coffee. Accordingly, considering the roasting intensity in highly valuable commercial samples, volume, mass, apparent density, moisture, total ash, ash insoluble in hydrochloric acid, and ether extract were characterized. The chromatic parameters L*, C*, Hº were measured using illuminants D65 and C. It was found that in roasted coffee beans, the parameters L*, C*, Hº, and coordinate b* had an antagonist interaction due to an increase in the roasting intensity, whereas after milling, only L* and Hº decreased progressively. Considering that the parameters L* and Hº followed similar patterns using both illuminants, D65 and C, it can be concluded that they are appropriate to evaluate coffee colour changes during roasting, enabling a relationship with coffee quality.Avaliaram-se indicadores não destrutivos e de execução rápida, para aferir a qualidade tecnológica de cafés Arábica e Robusta. Neste contexto, considerando a intensidade da torra em amostras com elevado interesse comercial, caracterizaram-se o volume, massa, densidade aparente, umidade, cinzas totais e insolúveis em ácido clorídrico e do extrato etéreo. Foram então analisados os parâmetros cromáticos L*, C*, Hº utilizando os iluminantes D65 e C. Verificou-se que em grãos de café torrado os parâmetros L*, C*, Hº e a coordenada b* mostraram uma interação antagônica face ao acréscimo da intensidade da torra, enquanto, após a moagem, apenas o L* e o Hº decresceram progressivamente. Considerando que a coordenada L* não variou significativamente com a aplicação dos dois iluminantes, concluiu-se que este parâmetro é o mais adequado para estudar a evolução da cor durante a torra, permitindo ainda estabelecer uma correlação com a qualidade.

  9. Proteinas do liquido cefalorraqueano: III. Valores normais das imuneglobulinas G, A e M (variações ligadas a cor, sexo e idade

    Directory of Open Access Journals (Sweden)

    Lucia M. Singer Vermes

    1983-03-01

    Full Text Available É apresentada inicialmente revisão de literatura a respeito dos resultados obtidos na determinação das taxas de imuneglobulinas do LCR normal, mediante diferentes métodos, assim como da influência dos fatores cor, sexo e idade, nestes valores. Mediante imunodifusão radial foram determinados os níveis de IgG, IgA e IgM do LCR normal de 115, 78 e 45 pessoas, respectivamente. Todas as amostras de LCR foram obtidas por punção sub-occipital (LCR-SO. Os resultados destas determinações permitiram concluir que: a as taxas médias de IgG, IgA e IgM do LCR de pretos ou pardos não diferem daquelas de brancos; b não existem variações ligadas ao sexo, nem à idade, em crianças com 1 a 11 anos, nas taxas das imuneglobulinas estudadas, no LCR; c os níveis fisiológicos em crianças com 1 a 11 anos, para IgG variam entre 0,21 e 2,93 mg/100 ml; os teores absolutos médios de IgG de crianças são inferiores àqueles encontrados em adultos; os níveis percentuais médios de IgG de crianças não diferem daqueles de adultos; d as taxas de IgA do LCR de crianças, tanto em valores absolutos como relativos, são, em média, inferiores àquelas encontradas em adultos, não ultrapassando, em condições normais, 0,15 mg/100 ml (0,7% do total protéico; e em adultos, não se observam variações ligadas ao sexo, nem à idade, nos níveis das imuneglobulinas estudadas, no LCR-SO; as taxas normais de IgG encontradas no LCR-SO de adultos são de 0,51 a 4,00 mg/100 ml; em crianças e adultos, as taxas fisiológicas desta imuneglobulina, em termos percentuais, são de 3 a 12%; o LCR-SO normal de adultos contém IgA em concentrações de até 0,32 mg/100 ml (0,9% do total protéico; f a IgM encontra-se no LCR-SO normal, tanto de crianças como de adultos, em níveis muito baixos, não ultrapassando 0,2 mg/100 ml (0,25% do total protéico.

  10. Relationship of plasma proadrenomedullin and cortisol levels with systemic inflammatory response and target organ damage in children with sepsis after burn

    Directory of Open Access Journals (Sweden)

    Xing Wei

    2017-08-01

    Full Text Available Objective: To study the relationship of plasma proadrenomedullin (pro-ADM and cortisol (Cor levels with systemic inflammatory response and target organ damage in children with sepsis after burn. Methods: A total of 30 children with sepsis after burn who were treated in the hospital between August 2014 and August 2016 were collected as observation group, and 30 normal children who received vaccination in the hospital during the same period were collected as normal control group. The pro-ADM and Cor levels in plasma as well as the levels of inflammatory factors, myocardial injury markers and intestinal barrier function indexes in serum of the two groups were determined. Pearson test was used to assess the correlation of plasma pro-ADM and Cor levels with systemic inflammatory response and target organ damage in patients with sepsis after burn. Results: Plasma pro-ADM and Cor levels in observation group were higher than those in normal control group. Serum inflammatory cytokines IL-1, IL-6, IL-10 and TNF-α levels in observation group were higher than those in normal control group; serum myocardial injury markers CK-MB, cTnⅠ and NT-proBNP levels were higher than those in normal control group; serum intestinal barrier function indexes ET, DAO and D-L levels were higher than those in normal control group. Conclusion: Plasma pro-ADM and Cor levels increase in patients with sepsis after burn, and are highly consistent with systemic inflammatory response and target organ injury.

  11. Restoration of the joint geometry and outcome after stemless TESS shoulder arthroplasty.

    Science.gov (United States)

    von Engelhardt, Lars V; Manzke, Michael; Breil-Wirth, Andreas; Filler, Timm J; Jerosch, Joerg

    2017-10-18

    To evaluate the joint geometry and the clinical outcome of stemless, anatomical shoulder arthroplasty with the TESS system. Twenty-one shoulders with a mean follow-up 18 of months were included. On scaled digital radiographs the premorbid center of rotation (CoR) was assessed and compared to the CoR of the prosthesis by using the MediCAD ® software. Additionally, the pre- and post-operative geometry of the CoR was assessed in relation to the glenoid, the acromion as well as to the proximal humerus. Radiological changes, such as radiolucencies, were also assessed. Clinical outcome was assessed with the Constant and DASH score. Both, the Constant and DASH scores improved significantly from 11% to 75% and from 70 to 30 points, P 0.05). The pre- and postoperative humeral offset, the lateral glenohumeral offset, the height of the CoR, the acromiohumeral distance as well as neck-shaft angle showed no significant changes ( P > 0.05). The mean deviation of the CoR of the prosthesis from the anatomic center was 1.0 ± 2.8 mm. Three cases showed a medial deviation of more than 3 mm. These deviations of 5.1, 5.7 and 7.6 mm and were caused by an inaccurate humeral neck cut. These 3 patients showed a relatively poor outcome scoring. TESS arthroplasty allows an anatomical joint reconstruction with a very good outcome. Outliers described in this study sensitize the surgeon for an accurate humeral neck cut.

  12. Tradisie-historiese probleme rondom 'versoening' by Paulus

    African Journals Online (AJOL)

    its roots in the diplomatic language of the Hellenistic era. Paul the legatus or presbeús (2 Cor 5:20) uses this concept to explain his function of mediating God's message of reconciliation to man (2 Cor 5:18f). True to his general presuppositions, Paul re-interprets the profane concept of katallage by stating that the death of ...

  13. Estudo pareado da cardiopatia chagásica no Rio Grande do Sul, Brasil: comportamento das alterações eletrocardiográficas em função da cor Matched study of Chagas cardiopaty in southerm Brazil: ECG alterations according to skin color

    Directory of Open Access Journals (Sweden)

    Giovanni Baruffa

    1987-09-01

    Full Text Available O trabalho analisa o comportamento das alterações eletrocardiográficas em 150 indivíduos de cor preta, naturais da área rural do sul do Rio Grande do Sul, pareados com outros tantos brancos do mesmo sexo, idade e procedência. O grupo tinha idade entre 9 e 78 anos, com média de 39,2 e era composto de 57 homens e 93 mulheres. Com referência à sorologia, 84 eram positivos e 66 negativos para a infecção pelo Trypanosoma cruzi. A prevalência de alterações eletrocardiográficas foi significativamente maior entre os pretos, tanto soropositivos quanto soronegativos. As alterações eletrocardiográficas consideradas sugestivas de miocardiopatia chagásica, predominaram significativamente entre os positivos pretos. E mesmo entre os pretos negativos as alterações foram mais numerosas e de maior gravidade com respeito aos negativos brancos. Na opinião dos autores a maior prevalência e severidade das alterações eletrocardiográficas entre os pretos, podem ser atribuídos a vários fatores entre os quais se destacariam: a pobreza e marginalidade das pessoas de cor que implicam trabalhos mais pesados e desgastantes; habitações triatomínica; alimentação mais pobre quantitativa e qualitativamente. Outro fator negativo seriam os valores mais elevados de pressão arterial encontrados entre os pretos que, associados a possíveis influências de ordem racial, podem contribuir e/ou criar condições de patologia miocárdica.The pattern of ECG changes of 150 black individuals from rural areas of southern Rio Grande do Sul, Brazil, was compared with that of a group of 150 whites of similar age, sex and geographical residence. The mean age of the study group was 39.2 years (9-78 years, and 62% were women. 84 out of the 150 showed positive serological reactions to infection by Trypanosoma cruzi. The prevalence of ECG changes was significantly higher among the blacks, irrespective of their serological state. Those changes which were considered as

  14. Determination of biocorrosion of low alloy steel by sulfate-reducing Desulfotomaculum sp. isolated from crude oil field

    Energy Technology Data Exchange (ETDEWEB)

    Cetin, D.; Doenmez, G. [Faculty of Science, Department of Biology, Ankara University, Tandogan, 06100, Ankara (Turkey); Bilgic, S. [Faculty of Science, Department of Chemistry, Ankara University, Tandogan, 06100, Ankara (Turkey); Doenmez, S. [Faculty of Engineering, Department of Food Engineering, Ankara University, Diskapi, 06110 Ankara (Turkey)

    2007-11-15

    In this study corrosion behavior of low alloy steel, in the presence of anaerobic sulfate-reducing Desulfotomaculum sp. which was isolated from an oil production well, was investigated. In order to determine corrosion rates and mechanisms, mass loss measurements and electrochemical polarization studies were performed without and with bacteria in the culture medium. Scanning electron microscopic observations and energy dispersive X-ray spectra (EDS) analysis were made on steel coupons. The effect of iron concentration on corrosion behavior was determined by Tafel extrapolation method. In a sterile culture medium, as the FeSO{sub 4} . 7H{sub 2}O concentration increased, corrosion potential (E{sub cor}) values shifted towards more anodic potentials and corrosion current density (I{sub cor}) values increased considerably. After inoculation of sulfate-reducing bacteria (SRB), E{sub cor} shifted towards cathodic values. I{sub cor} values increased with increasing incubation time for 10 and 100 mg/L concentrations of FeSO{sub 4} . 7H{sub 2}O. Results have shown that the corrosion activity changed due to several factors such as bacterial metabolites, ferrous sulfide, hydrogen sulfide, iron phosphide, and cathodic depolarization effect. (Abstract Copyright [2007], Wiley Periodicals, Inc.)

  15. Comparison of noninvasive assessments of central blood pressure using general transfer function and late systolic shoulder of the radial pressure wave.

    Science.gov (United States)

    Wohlfahrt, Peter; Krajcoviechová, Alena; Seidlerová, Jitka; Mayer, Otto; Filipovsky, Jan; Cífková, Renata

    2014-02-01

    Central systolic blood pressure (cSBP) can be derived by the general transfer function of the radial pressure wave, as used in the SphygmoCor device, or by regression equation from directly measured late systolic shoulder of the radial pressure wave (pSBP2), as used in the Omron HEM-9000AI device. The aim of this study was to compare the SphygmoCor estimates of cSBP with 2 estimates of cSBP provided by the Omron HEM-9000AI (cSBP, pSBP2) in a large cohort of the white population. In 391 patients aged 52.3±13.5 years (46% men) from the Czech post-MONICA Study, cSBP was measured using the SphygmoCor and Omron HEM-9000AI devices in random order. Omron cSBP and pSBP2 were perfectly correlated (r = 1.0; P wave provides a comparable accuracy with the validated general transfer function. When comparing Omron HEM-9000AI and SphygmoCor estimates of cSBP, Omron pSBP2 should be used. The difference between both devices in cSBP may be explained by differences in calibration.

  16. Age and Parkinson's disease-related neuronal death in the substantia nigra pars compacta

    DEFF Research Database (Denmark)

    Eriksen, Nina; Stark, Anette Kirstine; Pakkenberg, Bente

    2009-01-01

    During aging, decline in memory and cognitive abilities as well as motor weakening is of great concern. The dopaminergic system mediates some aspects of manual dexterity, in addition to cognition and emotion, and may be especially vulnerable to aging. A common neurodegenerative disorder of this s......During aging, decline in memory and cognitive abilities as well as motor weakening is of great concern. The dopaminergic system mediates some aspects of manual dexterity, in addition to cognition and emotion, and may be especially vulnerable to aging. A common neurodegenerative disorder...

  17. The Influence of Preprocessing Steps on Graph Theory Measures Derived from Resting State fMRI.

    Science.gov (United States)

    Gargouri, Fatma; Kallel, Fathi; Delphine, Sebastien; Ben Hamida, Ahmed; Lehéricy, Stéphane; Valabregue, Romain

    2018-01-01

    Resting state functional MRI (rs-fMRI) is an imaging technique that allows the spontaneous activity of the brain to be measured. Measures of functional connectivity highly depend on the quality of the BOLD signal data processing. In this study, our aim was to study the influence of preprocessing steps and their order of application on small-world topology and their efficiency in resting state fMRI data analysis using graph theory. We applied the most standard preprocessing steps: slice-timing, realign, smoothing, filtering, and the tCompCor method. In particular, we were interested in how preprocessing can retain the small-world economic properties and how to maximize the local and global efficiency of a network while minimizing the cost. Tests that we conducted in 54 healthy subjects showed that the choice and ordering of preprocessing steps impacted the graph measures. We found that the csr (where we applied realignment, smoothing, and tCompCor as a final step) and the scr (where we applied realignment, tCompCor and smoothing as a final step) strategies had the highest mean values of global efficiency (eg) . Furthermore, we found that the fscr strategy (where we applied realignment, tCompCor, smoothing, and filtering as a final step), had the highest mean local efficiency (el) values. These results confirm that the graph theory measures of functional connectivity depend on the ordering of the processing steps, with the best results being obtained using smoothing and tCompCor as the final steps for global efficiency with additional filtering for local efficiency.

  18. The Influence of Preprocessing Steps on Graph Theory Measures Derived from Resting State fMRI

    Directory of Open Access Journals (Sweden)

    Fatma Gargouri

    2018-02-01

    Full Text Available Resting state functional MRI (rs-fMRI is an imaging technique that allows the spontaneous activity of the brain to be measured. Measures of functional connectivity highly depend on the quality of the BOLD signal data processing. In this study, our aim was to study the influence of preprocessing steps and their order of application on small-world topology and their efficiency in resting state fMRI data analysis using graph theory. We applied the most standard preprocessing steps: slice-timing, realign, smoothing, filtering, and the tCompCor method. In particular, we were interested in how preprocessing can retain the small-world economic properties and how to maximize the local and global efficiency of a network while minimizing the cost. Tests that we conducted in 54 healthy subjects showed that the choice and ordering of preprocessing steps impacted the graph measures. We found that the csr (where we applied realignment, smoothing, and tCompCor as a final step and the scr (where we applied realignment, tCompCor and smoothing as a final step strategies had the highest mean values of global efficiency (eg. Furthermore, we found that the fscr strategy (where we applied realignment, tCompCor, smoothing, and filtering as a final step, had the highest mean local efficiency (el values. These results confirm that the graph theory measures of functional connectivity depend on the ordering of the processing steps, with the best results being obtained using smoothing and tCompCor as the final steps for global efficiency with additional filtering for local efficiency.

  19. The Influence of Preprocessing Steps on Graph Theory Measures Derived from Resting State fMRI

    Science.gov (United States)

    Gargouri, Fatma; Kallel, Fathi; Delphine, Sebastien; Ben Hamida, Ahmed; Lehéricy, Stéphane; Valabregue, Romain

    2018-01-01

    Resting state functional MRI (rs-fMRI) is an imaging technique that allows the spontaneous activity of the brain to be measured. Measures of functional connectivity highly depend on the quality of the BOLD signal data processing. In this study, our aim was to study the influence of preprocessing steps and their order of application on small-world topology and their efficiency in resting state fMRI data analysis using graph theory. We applied the most standard preprocessing steps: slice-timing, realign, smoothing, filtering, and the tCompCor method. In particular, we were interested in how preprocessing can retain the small-world economic properties and how to maximize the local and global efficiency of a network while minimizing the cost. Tests that we conducted in 54 healthy subjects showed that the choice and ordering of preprocessing steps impacted the graph measures. We found that the csr (where we applied realignment, smoothing, and tCompCor as a final step) and the scr (where we applied realignment, tCompCor and smoothing as a final step) strategies had the highest mean values of global efficiency (eg). Furthermore, we found that the fscr strategy (where we applied realignment, tCompCor, smoothing, and filtering as a final step), had the highest mean local efficiency (el) values. These results confirm that the graph theory measures of functional connectivity depend on the ordering of the processing steps, with the best results being obtained using smoothing and tCompCor as the final steps for global efficiency with additional filtering for local efficiency. PMID:29497372

  20. 75 FR 35045 - Authorization of Emergency Use of Certain In Vitro Diagnostic Devices; Availability

    Science.gov (United States)

    2010-06-21

    ..., Inc.) followed by rRT-PCR on the Applied Biosystems 7500 Real-Time PCR System. The ViraCor 2009 H1N1... detection systems are operating at the required level of sensitivity. The ViraCor 2009 H1N1 Influenza A Real... Real-Time PCR System with ABI Software: SDS software version 1.4. bioM[eacute]rieux NucliSENS[reg] easy...

  1. U.S.-Iraq Agreements: Congressional Oversight Activities and Legislative Response

    Science.gov (United States)

    2009-05-15

    Administration executed the Agreements as sole executive agreements, needing only the signature of Ambassador Crocker for entry into force, the Iraqi process for...parliamentary process . Several members of the COR asserted that it was unconstitutional to consider approval of the agreements because the COR had not yet...including a law to govern the referendum process , have not taken place to date. The Strategic Framework sets out broad

  2. Chino Décor Construction Nigeria Ltd.

    Institute of Scientific and Technical Information of China (English)

    You Wanlong

    2007-01-01

    @@ Q: What are the core industries of the investment of your company in Africa? A: In 1989 when I visited Africa for the first time, I went to Nigeria. In the coming decade, I struggled in Africa. I used to run a hotel; following, I struggled in the sphere of investment. Up to now, we have established the market strategy in Africa which bases on Nigeria.

  3. In vitro evaluation of dental bleaching effectiveness using hybrid lights activation = Avaliação in vitro da eficácia da fotoativação no clareamento dental utilizando a técnica em consultório

    Directory of Open Access Journals (Sweden)

    Araújo, Rodrigo Maximo de

    2010-01-01

    Full Text Available Objetivo: Avaliar se fontes de luz aumentam a eficácia do peróxido de hidrogênio na técnica de clareamento profissional. Metodologia: Foram empregados 60 dentes incisivos bovinos, com dimensões coronárias e radiculares padronizadas a partir do limite amelo-cementário, sendo descartada a porção lingual. Os corpos-de-prova (cp foram limpos em ultra-som por 20 min e a dentina condicionada com H3PO4 a 38% por 15 s, sendo os (cp imersos em solução de café solúvel a 25% por duas semanas. A dentina foi impermeabilizada com esmalte e os (cp divididos em 5 grupos, sendo a cor inicial mensurada através do espectofotômetro-EasyShade (VITA. Todos os (cp receberam três aplicações por 10 min do gel clareador Opalescence Xtra-Boost (Ultradent conforme segue: Grupo 1 – controle, não recebeu fotoativação, Grupo 2 – ativado com luz halôgena, Grupo 3 – ativado com LED azul/LASER, Grupo 4 – ativado com LED verde/LASER e Grupo 5 – ativado com LED vermelho. Após o clareamento foi mensurada a variação de cor ?E, ?a*, ?b*e ?L* e as referentes à escala de cor Vita Clássico. Os dados foram submetidos à análise de variância, teste de Tukey e de Dunn (a=5%. Resultados: A diferença geral da cor foi reduzida quando se empregou LED Azul e Luz Halógena, sendo que o desempenho do peróxido de hidrogênio a 38 % foi intensificado dependendo da fonte de luz utilizada. A avaliação quantitativa de cor, obtida por espectrofotômetro e pela escala de cor Vita Clássico, foram coincidentes. Conclusão: O tipo de fonte de luz empregada interfere na eficácia do agente clareador

  4. Coefficient of restitution of sports balls: A normal drop test

    International Nuclear Information System (INIS)

    Haron, Adli; Ismail, K A

    2012-01-01

    Dynamic behaviour of bodies during impact is investigated through impact experiment, the simplest being a normal drop test. Normally, a drop test impact experiment involves measurement of kinematic data; this includes measurement of incident and rebound velocity in order to calculate a coefficient of restitution (COR). A high speed video camera is employed for measuring the kinematic data where speed is calculated from displacement of the bodies. Alternatively, sensors can be employed to measure speeds, especially for a normal impact where there is no spin of the bodies. This paper compares experimental coefficients of restitution (COR) for various sports balls, namely golf, table tennis, hockey and cricket. The energy loss in term of measured COR and effects of target plate are discussed in relation to the material and construction of these sports balls.

  5. Leer a Maquiavelo, traducir el Corán: Muḥammad, príncipe y legislador en el Alcorano di Macometto (Venecia, 1547

    Directory of Open Access Journals (Sweden)

    Mattia Tommasino, Pier

    2013-02-01

    Full Text Available This article focuses on L’Alcorano di Macometto, written by Giovanni Battista Castrodardo from Belluno (1588 ca.-1517 ca., and published by Andrea Arrivabene at Venice in 1547. Although this text is considered to be a paraphrase of the Latin translation of the Qur’ān made by Robert of Ketton (1143 AD, a closer look shows that it was a handy pocket encyclopedia of the history of Islam and the Ottoman empire. Following a suggestion of Alessandro D’Ancona (1889, I analyze the historical texts published in the introduction to the Alcorano and especially Castrodardo’s biography of the prophet Muḥammad. This biography includes a prayer addressed to Muḥammad through the character of the monk Sergio-Bahīrā in order to persuade him to dethrone Emperor Heraclius. A deep linguistic analysis of this speech sheds light on Castrodardo’s reading of Machiavelli. While this new portrayal of Muhammad is based on medieval sources, it presents the Prophet of Islam as a distinctly Renaissance Prince, a lawgiver and a “Prophet Armed”. It also reflects the pro-Ottoman and anti-Imperial hopes of Italian circles linked to the French embassy in Venice.Este artículo se centra en L’Alcorano di Macometto, escrito por Giovanni Battista Castrodardo de Belluno (1517 ca.-1588 ca. e impreso por Andrea Arrivabene en Venecia en 1547. Aunque hoy sea considerado como una torpe paráfrasis de la traducción latina del Corán de Roberto de Ketton (1143 AD, un examen atento demuestra que L’Alcorano costituyó una práctica y exitosa enciclopedia de bolsillo sobre la historia del islam y del Imperio otomano. Siguiendo una intuición de Alessandro D’Ancona (1889, analizo los textos históricos publicados en la introducción del texto, centrándome especialmente en la biografía del profeta Muḥammad escrita por Castrodardo. Dicha biografía presenta una larga oración renacentista pronunciada por el monje Sergio-Bahīrā para convencer a Muḥammad a derrocar

  6. Role of medial premotor areas in action language processing in relation to motor skills.

    Science.gov (United States)

    Courson, Melody; Macoir, Joël; Tremblay, Pascale

    2017-10-01

    The literature reports that the supplementary motor area (SMA) and pre-supplementary motor area (pre-SMA) are involved in motor planning and execution, and in motor-related cognitive functions such as motor imagery. However, their specific role in action language processing remains unclear. In the present study, we investigated the impact of repetitive transcranial magnetic stimulation (rTMS) over SMA and pre-SMA during an action semantic analogy task (SAT) in relation with fine motor skills (i.e., manual dexterity) and motor imagery abilities in healthy non-expert adults. The impact of rTMS over SMA (but not pre-SMA) on reaction times (RT) during SAT was correlated with manual dexterity. Specifically, results show that rTMS over SMA modulated RT for those with lower dexterity skills. Our results therefore demonstrate a causal involvement of SMA in action language processing, as well as the existence of inter-individual differences in this involvement. We discuss these findings in light of neurolinguistic theories of language processing. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Surface EMG in advanced hand prosthetics.

    Science.gov (United States)

    Castellini, Claudio; van der Smagt, Patrick

    2009-01-01

    One of the major problems when dealing with highly dexterous, active hand prostheses is their control by the patient wearing them. With the advances in mechatronics, building prosthetic hands with multiple active degrees of freedom is realisable, but actively controlling the position and especially the exerted force of each finger cannot yet be done naturally. This paper deals with advanced robotic hand control via surface electromyography. Building upon recent results, we show that machine learning, together with a simple downsampling algorithm, can be effectively used to control on-line, in real time, finger position as well as finger force of a highly dexterous robotic hand. The system determines the type of grasp a human subject is willing to use, and the required amount of force involved, with a high degree of accuracy. This represents a remarkable improvement with respect to the state-of-the-art of feed-forward control of dexterous mechanical hands, and opens up a scenario in which amputees will be able to control hand prostheses in a much finer way than it has so far been possible.

  8. The Effect of Marginal Seal of Veneering DiCor (trade name) Substrates with DiCor Plus Porcelain

    Science.gov (United States)

    1991-05-01

    require less surface colorant. This combined with the darkness of the oral cavity may lower the value and give a restoration a gray appearance. 6. Minimal...of oral microbiota by cast glass-ceramic restoration. Int. J. Periodontics Restorative Dent. 2:23-35. Schaerer, P., Sato, T., and Wohlwend, A. 1988...or alloys containing zinc. He noted that cavity preparation had to be altered by making non-bevelled "square margins." As for fit, he reported it

  9. The Army Did Not Effectively Monitor Contractor Performance for the Kuwait Base Operations and Security Support Services Contract

    Science.gov (United States)

    2017-03-07

    and efficiency; advises the Secretary of Defense and Congress; and informs the public. Vision Our vision is to be a model oversight organization in...COR reports, nominations , appointments, and terminations to ensure an accurate list of COR personnel can be generated. ACC-RI, in coordination with...audit in accordance with generally accepted government auditing standards. During the audit, we advised ASG-KU, ACC-RI, and 408th CSB of the contract

  10. As redes de solidariedade da cor: o caso dos compadres Manoel e Lauriano The Colour Solidarity Networks: the case of the 'compadres' Manoel and Laurino

    Directory of Open Access Journals (Sweden)

    Ivan de Andrade Vellasco

    2006-01-01

    Full Text Available O artigo baseia-se na analise de um processo criminal de 1831, no qual os réus, pardos, são acusados de assassinar um homem branco. No teor dos depoimentos revela-se a formação de uma aliança solidária dos pardos, em função das categorias que definem as posições e juízos a respeito do crime. Testemunhas pardas e crioulas, livres e forras, produzem um consenso construindo uma versão contra a vítima, o homem branco. Uma visão sobre o certo e o errado solidariza a todos e, dentro dela, uma percepção específica da justiça une pardos, crioulos e cabras. Propõe-se que a solidariedade com base na identidade entre "pardos" possa ter tido uma intencionalidade e motivações associadas aos debates políticos da época, travados entre liberais moderados e conservadores, a respeito da conceituação e inclusão dos ‘pardos’ no projeto de nação. Representa uma tentativa de se captar, nos indícios disponíveis, a formação de processos identitários com base na cor e na condição, categorias ordenadoras fundamentais da sociedade escravista.This article is based on the analysis of a criminal lawsuit from 1831, in which the accused ones, who were "mulattos", were charged with a white man murder. In the testimonies of the lawsuit, it is possible to identify a supportive alliance among the "mulattos", in relation to the categories that define the positions and judgements concerning to the crime. Witnesses, both "mulattos" and "negros", free and manumitted slaves, have produced a consensus, hence building a version against the victim, the white man. A view on right and wrong promotes solidarity in everybody and, within this view, a specific perception about what unites "mulattos", "negros", manumitted slaves and "cabras". We propose that the solidarity based on the identity among the "mulattos" can be understood in relation to the motivations associated to their emersion in the political debates of the time, concerning to their

  11. Forced, not voluntary, exercise improves motor function in Parkinson's disease patients.

    Science.gov (United States)

    Ridgel, Angela L; Vitek, Jerrold L; Alberts, Jay L

    2009-01-01

    Animal studies indicate forced exercise (FE) improves overall motor function in Parkinsonian rodents. Global improvements in motor function following voluntary exercise (VE) are not widely reported in human Parkinson's disease (PD) patients. The aim of this study was to compare the effects of VE and FE on PD symptoms, motor function, and bimanual dexterity. Ten patients with mild to moderate PD were randomly assigned to complete 8 weeks of FE or VE. With the assistance of a trainer, patients in the FE group pedaled at a rate 30% greater than their preferred voluntary rate, whereas patients in the VE group pedaled at their preferred rate. Aerobic intensity for both groups was identical, 60% to 80% of their individualized training heart rate. Aerobic fitness improved for both groups. Following FE, Unified Parkinson's Disease Rating Scale (UPDRS) motor scores improved 35%, whereas patients completing VE did not exhibit any improvement. The control and coordination of grasping forces during the performance of a functional bimanual dexterity task improved significantly for patients in the FE group, whereas no changes in motor performance were observed following VE. Improvements in clinical measures of rigidity and bradykinesia and biomechanical measures of bimanual dexterity were maintained 4 weeks after FE cessation. Aerobic fitness can be improved in PD patients following both VE and FE interventions. However, only FE results in significant improvements in motor function and bimanual dexterity. Biomechanical data indicate that FE leads to a shift in motor control strategy, from feedback to a greater reliance on feedforward processes, which suggests FE may be altering central motor control processes.

  12. Energy transfer processes in Er-doped crystals

    International Nuclear Information System (INIS)

    Georgescu, Serban; Toma, Octavian

    2005-01-01

    In this paper, the microparameters characteristic to various energy-transfer processes in erbium doped crystals are estimated using the Dexter theory. For all the investigated processes, electric dipole-dipole interaction between donor and acceptor ions is assumed. The spectra appearing in Dexter's expression of the microparameter are simulated as a superposition of Lorentzian lines, knowing the positions of both initial and final Stark levels, and calibrated using the Judd-Ofelt model. This approach can give an estimation of the importance of the energy-transfer processes. (copyright 2005 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  13. Optimal percutaneous coronary intervention in patients with ST-elevation myocardial infarction and multivessel disease: An updated, large-scale systematic review and meta-analysis.

    Science.gov (United States)

    Nguyen, An Vu; Thanh, Le Van; Kamel, Mohamed Gomaa; Abdelrahman, Sara Attia Mahmoud; El-Mekawy, Mohamed; Mokhtar, Mohamed Ashraf; Ali, Aya Ashraf; Hoang, Nam Nguyen Nho; Vuong, Nguyen Lam; Abd-Elhay, Fatma Abd-Elshahed; Omer, Omer Abdelbagi; Mohamed, Ahmed Abdou; Hirayama, Kenji; Huy, Nguyen Tien

    2017-10-01

    Our study aimed to compare three different percutaneous coronary intervention (PCI) approaches: culprit-only (COR) and complete (CR) revascularization - categorizing into immediate (ICR) or staged (SCR). We searched 13 databases for randomized controlled trials. Articles were included if they compared at least two strategies. To have more studies in each analysis, an adjusted analysis was performed using person-years to incorporate follow-up durations and obtain pooled rate ratios (RR), with their corresponding 95% confidence interval. Thirteen trials were included with a population of 2830 patients. COR significantly increased major adverse cardiac event (MACE) (adjusted RR 1.67, 95% CI: 1.27-2.19) and repeat revascularization (2.12, 1.67-2.69), which was driven by repeat PCI, without any difference in all-cause mortality and myocardial infarction (MI) compared to CR. When categorizing CR into SCR and ICR, the trend repeated with COR increased MACE (1.99, 1.53-2.6 for ICR), cardiovascular mortality (2.06, 1.07-3.96 for ICR), MI for ICR (1.72, 1.04-2.86), repeat revascularization and repeat PCI for both ICR and SCR. Non-cardiovascular mortality, stroke, nephropathy, re-hospitalization, stent thrombosis and bleeding were similar among all approaches. In MVD-STEMI patients, CR is better than COR in terms of MACE, cardiovascular mortality, repeat revascularization with no difference in safety outcomes. There was a trend towards to a reduction of cardiovascular mortality and MI in ICR compared to SCR when each matched with COR; even though there is no statistically significant difference between ICR and SCR when compared together. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. 2008 annual site restoration report of the BC Oil and Gas Commission

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-15

    Oil and gas operators in British Columbia are responsible for all issues related to the surface reclamation of a site, including the management of contaminated sites. They require a certificate of restoration (CoR) for lands no longer required in the extraction of hydrocarbons. The CoR program ensures that the land used for oil and development is restored to a safe and productive state. The restoration process promotes the timely recovery of wellsite and facility locations and helps in managing environmental impacts. The BC Oil and Gas Commission oversees the restoration process by oil and gas operators through the application of regulations, compliance and enforcement. The Commission balances a broad range of environmental, economic and social considerations. Among its specific objectives are public safety, conservation of petroleum resources, promoting a healthy environment, and equitable participation in production. This report included a review of performance measures that have been developed to evaluate restoration programs, including well plugging. Site reclamation requirements for lands within the Agricultural Land Reserve (ALR) were also described along with orphan site reclamation activities. A CoR is issued after a permit holder demonstrates that the remediation criteria have been met. There are currently 3,814 sites that have received a CoR in the province. refs., tabs., figs.

  15. Update summary of the 1991 discharge of enriched uranium to the sanitary sewer (DEUSS) report

    International Nuclear Information System (INIS)

    1995-04-01

    Since the 1991 Y-12 Plant report, a flow study of the Y-12 Plant sanitary sewer collection system has been completed by the Y-12 Plant staff (Hanzelka and Maguire, 1993). Additional data has been obtained by the Y-12 Plant and the City of Oak Ridge (COR, 1994). COR developed limits on radionuclide concentrations in sludges used for land application (Stetar, 1993). Martin Marietta Energy Systems has provided recommendations to the Department of Energy (DOE) regarding the impacts of sludge land farming operations on the ORR (Frye, 1992). The DOE Office of Nuclear Safety (USDOE, 1993) completed an audit of activities related to radiological contamination of the COR sewer system due to DOE operations. In addition COR is currently developing limits on radionuclide releases for all industrial customers to be applied through the permitting process. In 1994, a new sanitary sewer monitoring station was installed and began operation at the Y-12 Plant to determine releases specifically from the Y-12 Plant. Previously, estimates were based on mass balance calculations using data from the City Monitoring Station which monitors Union Valley and Y-12 Plant releases. The purpose of this report is to update the 1991 Y-12 Plant study taking into account current data and information

  16. Taxonomic and floristic novelties for Echeveria ( Crassulaceae ) in Central Michoacan, Mexico

    OpenAIRE

    Garc?a-Ruiz, Ignacio; Valent?n-Mart?nez, Dagoberto; Carrillo-Reyes, Pablo; Costea, Mihai

    2016-01-01

    Abstract A new species, Echeveria coruana , is described and illustrated from the malpa?s near San Andr?s Cor?, Michoacan, Mexico. The species belongs to series Gibbiflorae and the new taxon was compared with Echeveria purhepecha and Echeveria patriotica , with whom it shares the closest morphological affinities. Additionally, Echeveria yalmanantlaensis an endangered species from Sierra of Manantl?n Biosphere Reserve, State of Colima, was also discovered near San Andr?s Cor? and is reported f...

  17. Proposed Continental Operations Range. United States Air Force.

    Science.gov (United States)

    1974-06-01

    sihject to the lesser constraints of COR East. This will occur as voon as comunications capability and radar surveillance will ,*.rr1t. The proposed COR...These communities are found at eleva- tionz mostly above the Pinon-Juniper Woodland comunities , or often in close association with them. The principal...species are relict or may have aesthe- tic and scientific value; (6) economic or recreational importance; and (7) various combinations of the above. The

  18. Composites in a Dexter-Based Hypermedia Framwork

    DEFF Research Database (Denmark)

    Grønbæk, Kaj

    1994-01-01

    with links to other components as in the classical systems such as NoteCards, Intermedia, and KMS. It is also shown how the powerful generic classes can be used to implement a variety of useful hypermedia concepts such as: hierarchy by inclusion, hierarchy by reference, virtual and computed browsers, Table...

  19. Human-like Compliance for Dexterous Robot Hands

    Science.gov (United States)

    Jau, Bruno M.

    1995-01-01

    This paper describes the Active Electromechanical Compliance (AEC) system that was developed for the Jau-JPL anthropomorphic robot. The AEC system imitates the functionality of the human muscle's secondary function, which is to control the joint's stiffness: AEC is implemented through servo controlling the joint drive train's stiffness. The control strategy, controlling compliant joints in teleoperation, is described. It enables automatic hybrid position and force control through utilizing sensory feedback from joint and compliance sensors. This compliant control strategy is adaptable for autonomous robot control as well. Active compliance enables dual arm manipulations, human-like soft grasping by the robot hand, and opens the way to many new robotics applications.

  20. Effect of the extract of persimmon (Diospyros kaki L. cv. ‘Rama Forte’and rosemary oily extract (Rosmarinus officinalis L. on the sensory characteristics and color stability of frozen beef burgersEfeito de extratos de caqui (Diospyros kaki L. cultivar Rama Forte e do extrato oleoso de alecrim (Rosmarinus officinalis L. nas características sensoriais e na estabilidade da cor de hambúrguer de carne bovina congelado

    Directory of Open Access Journals (Sweden)

    Leadir Lucy Martins Fries

    2012-06-01

    da cor de hambúrguer de carne bovina congelado. Para tanto foi elaborado o extrato hidroetanólico bruto que foi fracionado obtendo-se a fração hexânica, clorofórmica, de acetato de etila e a fração residual. Para o preparo das amostras de hambúrguer foi elaborada uma formulação básica que foi dividida em partes: controle, padrão (formulação adicionada de 0,1% de eritorbato de sódio, tratamento 1 (0,5% de extrato hidroetanólico bruto, tratamento 2 (0,7% de extrato hidroetanólico bruto, tratamento 3 (0,5% da fração residual, tratamento 4 (0,7% da fração residual, tratamento 5 (0,5% da fração acetato de etila, tratamento 6 (0,7% da fração acetato de etila e tratamento 7 (0,10% de extrato oleoso de alecrim. As amostras de hambúrguer foram armazenadas a –25 ºC por 14 meses e submetidas a análise sensorial (cor, aroma, sabor e textura no início do experimento e a determinação da cor (L*, a*, b* e h* a cada 2 meses. A adição dos extratos não promoveu alteração dos atributos sensoriais do hambúrguer bovino no tempo zero de armazenamento. Ocorreu tendência de diminuição dos valores de a* e aumento dos valores de h* das amostras de hambúrguer congeladas ao longo do período de armazenamento. As amostras adicionadas da fração acetato de etila (0,5 e 0,7% e do extrato oleoso de alecrim apresentaram maiores valores de a* que as demais amostras ao longo do período de armazenamento e menores valores de h* que a amostra padrão, no final do período avaliado, indicando que a adição da fração acetato de etila e do extrato de alecrim contribuiram na retenção e estabilidade da cor vermelha das amostras de hambúrguer de carne bovina durante o período de armazenamento do produto congelado.

  1. The feasibility of susceptibility weighted imaging for assessing renal difference of healthy volunteers after water loading

    International Nuclear Information System (INIS)

    Ding Jiule; Xing Wei; Chen Jie; Yu Shengnan; Qiu Jianguo; Xing Shijun; Sun Jun

    2013-01-01

    Objective: To probe the feasibility of susceptibility weighted imaging (SWI) for evaluation of renal blood oxygenation level of healthy volunteers after water loading. Methods: SWI of 11 healthy volunteers, acquired before (group 1) and after water loading (group 2), were assessed retrospectively by two radiologists with more than 10 years abdominal work experience independently. In those images of the same section plane derived from two groups, the phase values in cortex (φ cor ) and medulla (φ med ), difference between the same vein and surrounding tissue on phase map (△ φ ) were measured using SPIN software package, and the oxygen extraction fraction changes (△OEF) was calculated. The φ cor , φ med and △ φ between two groups were compared by paired t test. And the intraclass correlation coefficient (ICC) was used to evaluate the consistency between two radiologists. Results: For the radiologist 1, the φ cor , φ med and △ φ were (0.046 ± 0.019), (-0.014 ± 0.003) and (1.3 ± 0.4) rad in group 1, and were (0.047 ± 0.014), (-0.012 ± 0.005) and (1.1 ± 0.4) rad in group 2 respectively, and no significant change was found in φ cor and φ med after water loading (t = -0.589 and-0.206, P > 0.05 in all), except of in △ φ (t = 2.400, P < 0.01). For the radiologist 2, the φ cor , φ med and △ φ were (0.049 ± 0.011), (-0.012 ± 0.004) and (1.5 ±0.4) rad in Group 1, and were (0.046 ± 0.017), (-0.011 ± 0.003) and (1.3 ± 0.2) rad in group 2 respectively, there was no significant change in φ cor and φ med after water loading (t = 0.590 and -0.974, P > 0.05 in all), except of in △ φ (t = 2.760, P < 0.05). Between two radiologists, the ICC of φ cor , φ med and △ φ were 0.623, 0.472 and 0.328 in group 1 and 0.599, 0.442 and 0.445 in group 2 respectively. △OEF decreased about (-4.2 ± 2.3)% and (-4.3 ± 2.8)% measured by two radiologists respectively, and the consistency is good between two radiologists (ICC = 0.784). Conclusion: SWI

  2. Clarificação de caldo de cana-de-açúcar por peróxido de hidrogênio: efeito da presença de dextrana

    Directory of Open Access Journals (Sweden)

    Juliana Aparecida de Souza SARTORI

    2015-12-01

    Full Text Available Resumo A qualidade do açúcar cristal está diretamente associada à qualidade da cana-de-açúcar (Saccharum sp. entregue nas usinas e à eficiência do processo industrial. A dextrana é considerada um parâmetro de qualidade de matéria-prima, uma vez que sua presença indica que a cana-de-açúcar sofreu deterioração entre as etapas de corte e seu processamento. Durante o processamento do caldo, a dextrana pode interferir na eficiência do processo. Na etapa de clarificação, a sulfitação tem como principal objetivo promover a redução de cor ICUMSA do caldo de cana-de-açúcar. A cor ICUMSA é o parâmetro mais importante para a classificação comercial do açúcar no Brasil e quanto mais baixo o seu valor, mais claro é o açúcar. O peróxido de hidrogênio (H2O2 tem sido estudado na clarificação do caldo de cana-de-açúcar como possível agente clarificante em substituição ao sulfito, que apresenta contra-indicações à saúde respiratória humana. Teve-se como objetivo determinar o impacto da presença de dextrana na eficiência da redução de cor ICUMSA do caldo de cana-de-açúcar por peroxidação. Durante a peroxidação, a temperatura e o pH influenciaram significativamente na redução da cor ICUMSA do caldo, sendo que o aumento da temperatura, aumento da dose de peróxido de hidrogênio e diminuição do pH levaram à diminuição da cor ICUMSA. Os valores de dextrana utilizados (até 1.000 ppm não mostraram influência significativa na redução da cor do caldo de cana-de-açúcar, mas apresentaram interações significativas com os demais parâmetros.

  3. Comparison of postoperative pain and inflammation reaction in dogs undergoing preventive laparoscopic-assisted and incisional gastropexy

    OpenAIRE

    HARAGUCHI, Tomoya; KIMURA, Shiho; ITOH, Harumichi; NISHIKAWA, Shimpei; HIYAMA, Masato; TANI, Kenji; ISERI, Toshie; ITOH, Yoshiki; NAKAICHI, Munekazu; TAURA, Yasuho; ITAMOTO, Kazuhito

    2017-01-01

    This study compared the effects of postoperative pain and inflammation reaction after preventive laparoscopic-assisted gastropexy (LAG) and incisional gastropexy (IG) in 10 clinically normal Beagles. Surgical time, incision length, visual analog scale (VAS) score, University of Melbourne Pain Scale (UMPS) score, and plasma C-reactive protein (CRP), plasma cortisol (COR), and serum interleukin-6 (IL-6) levels were evaluated. The VAS and UMPS scores and COR and IL-6 levels were recorded at 0.5,...

  4. Deficits in vision and visual attention associated with motor performance of very preterm/very low birth weight children.

    Science.gov (United States)

    Geldof, Christiaan J A; van Hus, Janeline W P; Jeukens-Visser, Martine; Nollet, Frans; Kok, Joke H; Oosterlaan, Jaap; van Wassenaer-Leemhuis, Aleid G

    2016-01-01

    To extend understanding of impaired motor functioning of very preterm (VP)/very low birth weight (VLBW) children by investigating its relationship with visual attention, visual and visual-motor functioning. Motor functioning (Movement Assessment Battery for Children, MABC-2; Manual Dexterity, Aiming & Catching, and Balance component), as well as visual attention (attention network and visual search tests), vision (oculomotor, visual sensory and perceptive functioning), visual-motor integration (Beery Visual Motor Integration), and neurological status (Touwen examination) were comprehensively assessed in a sample of 106 5.5-year-old VP/VLBW children. Stepwise linear regression analyses were conducted to investigate multivariate associations between deficits in visual attention, oculomotor, visual sensory, perceptive and visual-motor integration functioning, abnormal neurological status, neonatal risk factors, and MABC-2 scores. Abnormal MABC-2 Total or component scores occurred in 23-36% of VP/VLBW children. Visual and visual-motor functioning accounted for 9-11% of variance in MABC-2 Total, Manual Dexterity and Balance scores. Visual perceptive deficits only were associated with Aiming & Catching. Abnormal neurological status accounted for an additional 19-30% of variance in MABC-2 Total, Manual Dexterity and Balance scores, and 5% of variance in Aiming & Catching, and neonatal risk factors for 3-6% of variance in MABC-2 Total, Manual Dexterity and Balance scores. Motor functioning is weakly associated with visual and visual-motor integration deficits and moderately associated with abnormal neurological status, indicating that motor performance reflects long term vulnerability following very preterm birth, and that visual deficits are of minor importance in understanding motor functioning of VP/VLBW children. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Repeatability of Retinal Sensitivity Measurements Using a Medmont Dark-Adapted Chromatic Perimeter in Healthy and Age-Related Macular Degeneration Cases.

    Science.gov (United States)

    Tan, Rose S; Guymer, Robyn H; Luu, Chi D

    2018-05-01

    To determine the intrasession and intersession test-retest repeatability of retinal sensitivity measurements using a dark-adapted chromatic perimeter (DACP). For intrasession testing, retinal sensitivity within the central 24° for the 505-nm stimulus was measured after 20, 30, and 40 minutes of dark adaptation (DA) and for the 625-nm stimulus was measured after the first and second 505-nm tests. For intersession testing, retinal sensitivity for both stimuli was measured after 30 minutes of DA at baseline and 1 month. The point-wise sensitivity (PWS) difference and coefficient of repeatability (CoR) of each stimulus and group were determined. For intrasession testing, 10 age-related macular degeneration (AMD) and eight control subjects were recruited. The overall CoR for the 505-nm stimulus was 8.4 dB for control subjects and 9.1 dB for AMD cases, and for the 625-nm stimulus was 6.7 dB for control subjects and 9.5 dB for AMD cases. For intersession testing, seven AMD cases and 13 control subjects returned an overall CoR for the 505-nm stimulus of 8.2 dB for the control and 11.7 dB for the AMD group. For the 625-nm stimulus the CoR was 6.2 dB for the control group and 8.4 dB for the AMD group. Approximately 80% of all test points had a PWS difference of ±5 dB between the two intrasession or intersession measurements for both stimuli. The CoR for the DACP is larger than that reported for scotopic perimeters; however, the majority of test points had a PWS difference of ±5 dB between tests. The DACP offers an opportunity to measure static and dynamic rod function at multiple locations with an acceptable reproducibility level.

  6. Fractures as an independent predictor of functional decline in older people: a population-based study with an 8-year follow-up.

    Science.gov (United States)

    Piirtola, Maarit; Löppönen, Minna; Vahlberg, Tero; Isoaho, Raimo; Kivelä, Sirkka-Liisa; Räihä, Ismo

    2012-01-01

    Fractures among older people are common, but there is scant evidence about the impact of fractures on functional decline in an unselected older population. The objective of this study was to analyze the impact of lower and upper body fractures on functional performance among older adults during an 8-year follow-up. A population-based cohort of 616 Finnish persons aged 65 and over was followed for up to 8 years, and the association between fractures and the risk of short-term (0-2 years) and long-term (up to 8 years) functional decline was analyzed. Fractures were categorized according their functional influence on mobility and activities of daily living (ADL) into lower and upper body fractures. Multivariate cumulative logistic regression model was used in the analyses. During the 8-year follow-up, 112 (18%) persons sustained at least one fracture. In the multivariate analyses, lower body fractures predicted both short-term and long-term decline in mobility [cumulative odds ratio (COR) 4.7, 95% confidence interval (95% CI) 1.9-11.7 and COR 2.6, 95% CI 1.1-6.2, respectively] and in ADL performance (COR 3.1, 95% CI 1.3-7.6 and COR 4.7, 95% CI 2.0-11.4, respectively). Upper body fractures predicted decline in ADL performance during the long-term follow-up (COR 2.5, 95% CI 1.3-4.8). Pre-fracture functional decline and inactivity in leisure time physical exercise were independently associated with the risk of decline in extensive activities. Fractures have an independent influence on the development of functional decline in older persons regardless of the pre-fracture health. Prevention of falls and fractures and improvement of treatment, rehabilitation and follow-up process after fractures are needed. Copyright © 2011 S. Karger AG, Basel.

  7. Radiation dose of cone-beam computed tomography compared to conventional radiographs in orthodontics.

    Science.gov (United States)

    Signorelli, Luca; Patcas, Raphael; Peltomäki, Timo; Schätzle, Marc

    2016-01-01

    The aim of this study was to determine radiation doses of different cone-beam computed tomography (CBCT) scan modes in comparison to a conventional set of orthodontic radiographs (COR) by means of phantom dosimetry. Thermoluminescent dosimeter (TLD) chips (3 × 1 × 1 mm) were used on an adult male tissue-equivalent phantom to record the distribution of the absorbed radiation dose. Three different scanning modes (i.e., portrait, normal landscape, and fast scan landscape) were compared to CORs [i.e., conventional lateral (LC) and posteroanterior (PA) cephalograms and digital panoramic radiograph (OPG)]. The following radiation levels were measured: 131.7, 91, and 77 μSv in the portrait, normal landscape, and fast landscape modes, respectively. The overall effective dose for a COR was 35.81 μSv (PA: 8.90 μSv; OPG: 21.87 μSv; LC: 5.03 μSv). Although one CBCT scan may replace all CORs, one set of CORs still entails 2-4 times less radiation than one CBCT. Depending on the scan mode, the radiation dose of a CBCT is about 3-6 times an OPG, 8-14 times a PA, and 15-26 times a lateral LC. Finally, in order to fully reconstruct cephalograms including the cranial base and other important structures, the CBCT portrait mode must be chosen, rendering the difference in radiation exposure even clearer (131.7 vs. 35.81 μSv). Shielding radiation-sensitive organs can reduce the effective dose considerably. CBCT should not be recommended for use in all orthodontic patients as a substitute for a conventional set of radiographs. In CBCT, reducing the height of the field of view and shielding the thyroid are advisable methods and must be implemented to lower the exposure dose.

  8. The Bacterial Effector HopX1 Targets JAZ Transcriptional Repressors to Activate Jasmonate Signaling and Promote Infection in Arabidopsis

    Science.gov (United States)

    Gimenez-Ibanez, Selena; Boter, Marta; Fernández-Barbero, Gemma; Chini, Andrea; Rathjen, John P.; Solano, Roberto

    2014-01-01

    Pathogenicity of Pseudomonas syringae is dependent on a type III secretion system, which secretes a suite of virulence effector proteins into the host cytoplasm, and the production of a number of toxins such as coronatine (COR), which is a mimic of the plant hormone jasmonate-isoleuce (JA-Ile). Inside the plant cell, effectors target host molecules to subvert the host cell physiology and disrupt defenses. However, despite the fact that elucidating effector action is essential to understanding bacterial pathogenesis, the molecular function and host targets of the vast majority of effectors remain largely unknown. Here, we found that effector HopX1 from Pseudomonas syringae pv. tabaci (Pta) 11528, a strain that does not produce COR, interacts with and promotes the degradation of JAZ proteins, a key family of JA-repressors. We show that hopX1 encodes a cysteine protease, activity that is required for degradation of JAZs by HopX1. HopX1 associates with JAZ proteins through its central ZIM domain and degradation occurs in a COI1-independent manner. Moreover, ectopic expression of HopX1 in Arabidopsis induces the expression of JA-dependent genes, represses salicylic acid (SA)-induced markers, and complements the growth of a COR-deficient P. syringae pv. tomato (Pto) DC3000 strain during natural bacterial infections. Furthermore, HopX1 promoted susceptibility when delivered by the natural type III secretion system, to a similar extent as the addition of COR, and this effect was dependent on its catalytic activity. Altogether, our results indicate that JAZ proteins are direct targets of bacterial effectors to promote activation of JA-induced defenses and susceptibility in Arabidopsis. HopX1 illustrates a paradigm of an alternative evolutionary solution to COR with similar physiological outcome. PMID:24558350

  9. Monitoring Vertical Crustal Deformation and Gravity Variations during Water Level Changes at the Three Gorges Reservoir

    Directory of Open Access Journals (Sweden)

    WANG Wei

    2017-06-01

    Full Text Available Monitoring vertical crustal deformation and gravity changes during water level changes at the Three Gorges reservoir is important for the safe operation of the Three Gorges Dam and for the monitoring and prevention of a regional geological disaster. In this study, we determined vertical crustal deformation and gravity changes during water level variations of the Three Gorges reservoir from direct calculations and actual measurements and a comprehensive solution. We used water areas extracted image data from the ZY-3 satellite and water level data to calculate gravity changes and vertical crustal deformation caused by every 5 m change in the water level due to storage and drainage of the Three Gorges reservoir from 145 m to 175 m. The vertical crustal deformation was up to 30 mm. The location of gravity change above 20 μ Gal(1 Gal=10-2 m/s2 was less than 2 km from the centerline of the Yangtze River. The CORS ES13 in Badong, near the reservoir, measured the vertical crustal deformation during water level changes. Because of the small number of CORS and gravity stations in the Three Gorges reservoir area, monitoring deformation and gravity related to changes in the Three Gorges reservoir water level cannot be closely followed. Using 26 CORS and some of the gravity stations in the Three Gorges area and based on loading deformation and the spherical harmonic analysis method, an integrated solution of vertical deformation and gravity variations during water level changes of the reservoir was determined, which is consistent with the actual CORS monitoring results. By comparison, we found that an integrated solution based on a CORS network can effectively enhance the capability of monitoring vertical crustal deformation and gravity changes during water level variations of the reservoir.

  10. FIRST MEASUREMENTS OF THE MASS OF CORONAL MASS EJECTIONS FROM THE EUV DIMMING OBSERVED WITH STEREO EUVI A+B SPACECRAFT

    International Nuclear Information System (INIS)

    Aschwanden, Markus J.; Nitta, Nariaki V.; Wuelser, Jean-Pierre; Lemen, James R.; Sandman, Anne; Vourlidas, Angelos; Colaninno, Robin C.

    2009-01-01

    The masses of coronal mass ejections (CMEs) have traditionally been determined from white-light coronagraphs (based on Thomson scattering of electrons), as well as from extreme ultraviolet (EUV) dimming observed with one spacecraft. Here we develop an improved method of measuring CME masses based on EUV dimming observed with the dual STEREO/EUVI spacecraft in multiple temperature filters that includes three-dimensional volume and density modeling in the dimming region and background corona. As a test, we investigate eight CME events with previous mass determinations from STEREO/COR2, of which six cases are reliably detected with the Extreme Ultraviolet Imager (EUVI) using our automated multi-wavelength detection code. We find CME masses in the range of m CME = (2-7) x 10 15 g. The agreement between the two EUVI/A and B spacecraft is m A /m B = 1.3 ± 0.6 and the consistency with white-light measurements by COR2 is m EUVI /m COR2 = 1.1 ± 0.3. The consistency between EUVI and COR2 implies no significant mass backflows (or inflows) at r sun and adequate temperature coverage for the bulk of the CME mass in the range of T ∼ 0.5-3.0 MK. The temporal evolution of the EUV dimming allows us to also model the evolution of the CME density n e (t), volume V(t), height-time h(t), and propagation speed v(t) in terms of an adiabatically expanding self-similar geometry. We determine e-folding EUV dimming times of t D = 1.3 ± 1.4 hr. We test the adiabatic expansion model in terms of the predicted detection delay (Δt ∼ 0.7 hr) between EUVI and COR2 for the fastest CME event (2008 March 25) and find good agreement with the observed delay (Δt ∼ 0.8 hr).

  11. A Comparison between Two Force-Position Controllers with Gravity Compensation Simulated on a Humanoid Arm

    Directory of Open Access Journals (Sweden)

    Giovanni Gerardo Muscolo

    2013-01-01

    Full Text Available The authors propose a comparison between two force-position controllers with gravity compensation simulated on the DEXTER bioinspired robotic arm. The two controllers are both constituted by an internal proportional-derivative (PD closed-loop for the position control. The force control of the two systems is composed of an external proportional (P closed-loop for one system (P system and an external proportional-integrative (PI closed-loop for the other system (PI system. The simulation tests performed with the two systems on a planar representation of the DEXTER, an eight-DOF bioinspired arm, showed that by varying the stiffness of the environment, with a correct setting of parameters, both systems ensure the achievement of the desired force regime and with great precision the desired position. The two controllers do not have large differences in performance when interacting with a lower stiffness environment. In case of an environment with greater rigidity, the PI system is more stable. The subsequent implementation of these control systems on the DEXTER robotic bioinspired arm gives guidance on the design and control optimisation of the arms of the humanoid robot named SABIAN.

  12. Correlation Between Ability on Playing Tetris and GPA

    Directory of Open Access Journals (Sweden)

    Aprilia Ratna Christanti

    2014-10-01

    Full Text Available The goal of this study is to determine the correlation between ability on playing Tetris and GPA of Soegijapranata Catholic University, Department of Information System students against the dexterity in playing Tetris. The research has been done using experiment method on ten Information System students who have various grade points. They played Tetris, 30 minutes each, for three consecutive days. The results showed that: First, eight out of the ten students improved their agility. It can be seen from the increasing scores and levels; Second, the coefficient correlation between student grade point and dexterity in playing Tetris is by 62%. Keywords Ability, grade point average, Tetris

  13. The excretory system of the liver in wild animals. VI. Biliary ducts of the great anteater (Myrmecophaga tridactyla

    Directory of Open Access Journals (Sweden)

    Maria Angélica Miglino

    1992-12-01

    Full Text Available The systematization of the biliary ducts of the liver of the great anteater (Myrmecophaga tridactyla is analyzed. The ductus choledocus has no affluents and results from the union of the ductus cysticus and the ductus hepaticus always arises from theramus principalis dexter and the ramus principalis sinister, and is seen without tributaries in three cases, receiving them meanwhile in the other one. The ramus principalis dexter is made up of the ramus lateralis lobi dextri and the ramus medialis lobi dextri. The ramus principalis sinister is formed by the ramus lateralis lobi sinistri, the ramus lobi sinistri and the ramus lobi quadrati.

  14. Evaluation of Biomass Yield and Water Treatment in Two Aquaponic Systems Using the Dynamic Root Floating Technique (DRF

    Directory of Open Access Journals (Sweden)

    Laura Silva

    2015-11-01

    Full Text Available The experiment evaluates the food production and water treatment of TAN, NO2−–N, NO3−–N, and PO43− in two aquaponics systems using the dynamic root floating technique (DRF. A separate recirculation aquaculture system (RAS was used as a control. The fish cultured was Nile tilapia (Oreochromis niloticus. The hydroponic culture in one treatment (PAK was pak choy (Brassica chinensis, and in the other (COR coriander (Coriandrum sativum. Initial and final weights were determined for the fish culture. Final edible fresh weight was determined for the hydroponic plant culture. TAN, NO2−–N, NO3−–N, and PO43− were measured in fish culture and hydroponic culture once a week at two times, morning (9:00 a.m. and afternoon (3:00 p.m.. The fish biomass production was not different in any treatment (p > 0.05 and the total plant yield was greater (p < 0.05 in PAK than in COR. For the hydroponic culture in the a.m., the PO43− was lower (p < 0.05 in the PAK treatment than in COR, and in the p.m. NO3−–N and PO43− were lower (p < 0.05 in PAK than in COR. The PAK treatment demonstrated higher food production and water treatment efficiency than the other two treatments.

  15. Trusted Data Communication and Security Issues in Gnss Network of Turkey

    Science.gov (United States)

    Bakici, S.; Erkek, B.; Manti, V.; Altekin, A.

    2017-11-01

    There are three main activities of General Directorate of Land Registry and Cadastre. These are Mapping, Land Registry and Cadastre. Geomatic Department is responsible for mapping activities. The most important projects like TUSAGA-Aktif (CORS-Tr), Metadata Geoportal, Orthophoto Production and orthophoto web services and preparation of Turkish NSDI Feasibility Report have been conducted and completed by this department's specialists since 2005. TUSAGA-Aktif (CORS-Tr) System, serves location information at cm level accuracy in Turkey and TR Nortern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-Tr System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre and to the control center located in the General Command of Mapping. Currently CORS-Tr has more than 9000 users. Most of them are private companies working for governmental organization. Providing data communication between control center and both GNSS station and users via trusted and good substructure is important. Additionally, protection of the system and data against cyber attacks from domestic and foreign sources is important. This paper focuses on data communication and security issues of GNSS network named TUSAGA-Aktif.

  16. CORÍN TELLADO Y LA NOVELA ROSA

    Directory of Open Access Journals (Sweden)

    Encarna Alonso Valero

    2012-07-01

    Full Text Available Resumen: Las novelas de Corín Tellado marcaron la vida de varias generaciones de mujeres y también de muchos hombres. Sufrió los reproches habituales a la novela comercial y de éxito, además del desprecio dedicado a la llamada novela rosa al ser considerada un género menor y fundamentalmente para mujeres. En este artículo nos proponemos analizar cómo con frecuencia ese tipo de juicios no son literarios sino sociales, juicios sociales denegados. Además, estudiaremos las novelas de Corín Tellado, que influyeron enormemente en la “educación sentimental” de las mujeres durante el franquismo, y analizaremos el modelo de mujer que presentan. Abstract: The novels of Corín Tellado marked the life of several generations of women, as well as of many men. She suffered the criticisms habitually levelled at commercially successful novels, especially the so-called novela rosa, or popular romance novel, because of its reputation as a minor genre aimed primarily at women. This paper aims to show that these judgments are often not literary but social. The paper will also examine Corín Tellado's novels, which greatly influenced the 'sentimental education' of women during the Franco regime, and we will analyze the models of woman that theses romances present.

  17. TRUSTED DATA COMMUNICATION AND SECURITY ISSUES IN GNSS NETWORK OF TURKEY

    Directory of Open Access Journals (Sweden)

    S. Bakici

    2017-11-01

    Full Text Available There are three main activities of General Directorate of Land Registry and Cadastre. These are Mapping, Land Registry and Cadastre. Geomatic Department is responsible for mapping activities. The most important projects like TUSAGA-Aktif (CORS-Tr, Metadata Geoportal, Orthophoto Production and orthophoto web services and preparation of Turkish NSDI Feasibility Report have been conducted and completed by this department’s specialists since 2005. TUSAGA-Aktif (CORS-Tr System, serves location information at cm level accuracy in Turkey and TR Nortern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-Tr System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre and to the control center located in the General Command of Mapping. Currently CORS-Tr has more than 9000 users. Most of them are private companies working for governmental organization. Providing data communication between control center and both GNSS station and users via trusted and good substructure is important. Additionally, protection of the system and data against cyber attacks from domestic and foreign sources is important. This paper focuses on data communication and security issues of GNSS network named TUSAGA-Aktif.

  18. Biomechanical Differences Between Toe and Instep Kicking; Influence of Contact Area on the Coefficient of Restitution

    DEFF Research Database (Denmark)

    Andersen, T. Bull; Sørensen, Henrik; Kristensen, Lars Bo

    2008-01-01

    The coefficient of restitution (COR) was determined for toe and instep soccer kicks. Furthermore, experiments were performed with a pendulum that modeled the different impact areas in toe and instep kicking. Six sub-elite soccer players performed 20 toe and 20 instep kicks with no run-up at a range...... and after impact. In the pendulum experiments the COR was larger for the small area (Toe) at all velocities, whereas this only was found at the lower velocities (areas in the two...

  19. A Synopsis of Acquisition Related Topics.

    Science.gov (United States)

    1983-03-01

    practices, ov.rnmen-. regulations and the economic environment . As with any other reference manual, this thesis will need to be up.la:ed and supplemented...construction cor:tracts Ccpeland "Anti- 18 USC 874 Prohibits kickbacks Kickback" Act 40 USC 276c from employees on public works Maybank Azendment Annual...ttismsnt by enccuraging challenge c. cor.trac-’rs’ dAD reca.ion methods: If the method selaec.ed is also use=d for external finarcial reporting a-id :Ls

  20. Preferential superior surface motion in wear simulations of the Charité total disc replacement.

    Science.gov (United States)

    Goreham-Voss, Curtis M; Vicars, Rachel; Hall, Richard M; Brown, Thomas D

    2012-06-01

    Laboratory wear simulations of the dual-bearing surface Charité total disc replacement (TDR) are complicated by the non-specificity of the device's center of rotation (CoR). Previous studies have suggested that articulation of the Charité preferentially occurs at the superior-bearing surface, although it is not clear how sensitive this phenomenon is to lubrication conditions or CoR location. In this study, a computational wear model is used to study the articulation kinematics and wear of the Charité TDR. Implant wear was found to be insensitive to the CoR location, although seemingly non-physiologic endplate motion can result. Articulation and wear were biased significantly to the superior-bearing surface, even in the presence of significant perturbations of loading and friction. The computational wear model provides novel insight into the mechanics and wear of the Charité TDR, allowing for better interpretation of in vivo results, and giving useful insight for designing future laboratory physical tests.