Kinetic advantage of controlled intermediate nuclear fusion

International Nuclear Information System (INIS)

Guo Xiaoming

2012-01-01

The dominated process of controlled fusion is to let nuclei gain enough kinetic energy to overcome Coulomb barrier. As a result, a fusion scheme can consider two factors in its design: to increase kinetic energy of nuclei and to alter the Coulomb barrier. Cold Fusion and Hot fusion are all one-factor schemes while Intermediate Fusion is a twofactors scheme. This made CINF kinetically superior. Cold Fusion reduces deuteron-deuteron distance, addressing Coulomb barrier, and Hot Fusion heat up plasma into extreme high temperature, addressing kinetic energy. Without enough kinetic energy made Cold Fusion skeptical. Extreme high temperature made Hot Fusion very difficult to engineer. Because CIFN addresses both factors, CIFN is a more promising technique to be industrialized.

Controlled thermonuclear fusion

International Nuclear Information System (INIS)

Trocheris, M.

1975-01-01

An outline is given of the present position of research into controlled fusion. After a brief reminder of the nuclear reactions of fusion and the principle of their use as a source of energy, the results obtained by the method of magnetic confinement are summarized. Among the many solutions that have been imagined and tried out to achieve a magnetic containing vessel capable of holding the thermonuclear plasma, the devices of the Tokamak type have a good lead and that is why they are described in greater detail. An idea is then given of the problems that arise when one intends conceiving the thermonuclear reactor based on the principle of the Tokamaks. The last section deals with fusion by lasers which is a new and most attractive alternative, at least from the viewpoint of basis physics. The report concludes with an indication of the stages to be passed through to reach production of energy on an industrial scale [fr

History of controlled nuclear fusion in Japan

International Nuclear Information System (INIS)

Uematsu, Eisui; Nishio, Shigeko; Takeda, Tatsuoki

2001-01-01

A research development of nuclear fusion was divided four periods: the first period as prehistory (until about 1955), the second period as begin of research (1955 to 1969), the third as the growth period (1970 to 1985) and the forth as the large tokamak age. In this paper I explained the second period, because general physicists and young plasma and controlled nuclear fusion researcher did not know about this period. The controlled nuclear fusion research was begun by the experiment of hydrogen bomb by USA and USSR in 1952 and 1953. In Japan, on the basis of many societies, 'The Controlled Nuclear Fusion Meeting' was established as an independent system and KAKEA (Journal of Fusion Research) was published in 1958. Japan government began to make the system by the Nuclear Commission in 1957. The main research devices in 1962 were linear pinch, mirror device, toroidal pinch, helical system, plasma gun and plasma measurement. USSR showed the excellent results of tokamak device in 1968. Ookawa spoke the effect of the average minimum-B, the best report in this period, at the second IAEA meeting, 1965. JAERI constructed JFT-1 and JFT-2, the latter was the first class device in the world and made the first step of Japanese research into the world, for examples, to attain the equilibrium of divertor plasma and to control impurity. Many research centers of controlled fusion were established in many universities in Japan from 1966 to 1980. Cooperation researchs between Japan and USA, USSR and many countries has been carried out after 1978: JIFT (Joint Institute for Fusion Theory) and FPPC (Fusion Power Coordinating Committee). The important results increased in this period. After 1985, the research activities are processing and data increased very fast depend on the larger devices and system, good measurement system and development of information system. JT-60 in JAERI opened to the large tokamak period. It led controlled fusion researchs in the world the same as TFTR (US

Controlled Nuclear Fusion: Status and Outlook

Science.gov (United States)

Rose, David J.

1971-01-01

Presents the history, current concerns and potential developments of nuclear fusion as a major energy source. Controlled fusion research is summarized, technological feasibility is discussed and environmental factors are examined. Relationships of alternative energy sources as well as energy utilization are considered. (JM)

Controlled nuclear fusion apparatus

International Nuclear Information System (INIS)

Bussard, R.W.; Coppi, B.

1982-01-01

A fusion power generating device is disclosed having a relatively small and inexpensive core region which may be contained within an energy absorbing blanket region. The fusion power core region contains apparatus of the toroidal type for confining a high density plasma. The fusion power core is removable from the blanket region and may be disposed and/or recycled for subsequent use within the same blanket region. Thermonuclear ignition of the plasma is obtained by feeding neutral fusible gas into the plasma in a controlled manner such that charged particle heating produced by the fusion reaction is utilized to bootstrap the device to a region of high temperatures and high densities wherein charged particle heating is sufficient to overcome radiation and thermal conductivity losses. The high density plasma produces a large radiation and particle flux on the first wall of the plasma core region thereby necessitating replacement of the core from the blanket region from time to time. A series of potentially disposable and replaceable central core regions are disclosed for a large-scale economical electrical power generating plant

Breeder control fusion reactor. Topical interview

Energy Technology Data Exchange (ETDEWEB)

Schlueter, A [Max-Planck-Institut fuer Plasmaphysik, Garching/Muenchen (Germany, F.R.)

1977-09-01

The energy sources of the future are extremely controversial. The consumption of fossil fuel shall decrease during the next decades, because exhaustion of the resources, pollution, increase of CO/sub 2/ in the atmosphere and other reasons. But at present the question it not yet settled which alternative energy system should replace the fossil fuel. First of all nuclear energy in the form of fission reactions seems to come into operation to a larger extent. The next step may be the controlled thermonuclear fusion reaction. Furthermore, a comparison between fusion and fission is given which shows that fusion would bring about less risks than the breeders. An advantage of the fusion reactor would be the fact that the fuel cycle is closed. Unfortunately, the physical questions are not as yet satisfactorily clarified so that one cannot be sure whether a fusion reactor can really be built.

Essential Role of DAP12 Signaling in Macrophage Programming into a Fusion-Competent State

Science.gov (United States)

Helming, Laura; Tomasello, Elena; Kyriakides, Themis R.; Martinez, Fernando O.; Takai, Toshiyuki; Gordon, Siamon; Vivier, Eric

2009-01-01

Multinucleated giant cells, formed by fusion of macrophages, are a hallmark of granulomatous inflammation. With a genetic approach, we show that signaling through the adaptor protein DAP12 (DNAX activating protein of 12 kD), its associated receptor triggering receptor expressed by myeloid cells 2 (TREM-2), and the downstream protein tyrosine kinase Syk is required for the cytokine-induced formation of giant cells and that overexpression of DAP12 potentiates macrophage fusion. We also present evidence that DAP12 is a general macrophage fusion regulator and is involved in modulating the expression of several macrophage-associated genes, including those encoding known mediators of macrophage fusion, such as DC-STAMP and Cadherin 1. Thus, DAP12 is involved in programming of macrophages through the regulation of gene and protein expression to induce a fusion-competent state. PMID:18957693

FireSignal application Node for subsystem control

International Nuclear Information System (INIS)

Duarte, A.S.; Santos, B.; Pereira, T.; Carvalho, B.B.; Fernandes, H.; Neto, A.; Janky, F.; Cahyna, P.; Pisacka, J.; Hron, M.

2010-01-01

Modern fusion experiments require the presence of several subsystems, responsible for the different parameters involved in the operation of the machine. With the migration from the pre-programmed to the real-time control paradigm, their integration in Control, Data Acquisition, and Communication (CODAC) systems became an important issue, as this implies not only the connection to a main central coordination system, but also communications with related diagnostics and actuators. A subsystem for the control and operation of the vacuum, gas injection and baking was developed and installed in the COMPASS tokamak. These tasks are performed by dsPIC microcontrollers that receive commands from a hub computer and send information regarding the status of the operation. Communications are done in the serial protocol RS-232 through fibre optics. Java software, with an intuitive graphical user interface, for controlling and monitoring of the subsystem was developed and installed in a hub computer. In order to allow operators to perform these tasks remotely besides locally, this was integrated in the FireSignal system. Taking advantage of FireSignal features, it was possible to provide the users with, not only the same functionalities of the local application but also a similar user interface. An independent FireSignal Java Node bridges the central server and the control application. This design makes possible to easily reuse the Node for other subsystems or integrate the vacuum slow control in the other CODAC systems. The complete system, with local and remote control, has been installed successfully on COMPASS and has been in operation since April this year.

FireSignal Application Node for Subsystem Control

Energy Technology Data Exchange (ETDEWEB)

Duarte, A.; Santos, B.; Pereira, T.; Carvalho, B.; Fernandes, H. [Instituto de Plasmas e Fusao Nuclear - Instituto Superior Tecnico, Lisbon (Portugal); Cahyna, P.; Pisacka, J.; Hron, M. [Institute of Plasma Physics AS CR, Association EURATOM/IPP.CR, Prague (Czech Republic)

2009-07-01

Modern fusion experiments require the presence of several sub-systems, responsible for the different parameters involved in the operation of the machine. With the migration from the pre-programmed to the real-time control paradigm, their integration in Control, Data Acquisition, and Communication (CODAC) systems became an important issue, as this implies not only the connection to a main central coordination system, but also communications with related diagnostics and actuators. A sub-system for the control and operation of the vacuum, gas injection and baking was developed and installed in the COMPASS tokamak. These tasks are performed by 'dsPIC' micro-controllers that receive commands from a computer and send information regarding the status of the operation. Communications are done in the serial protocol RS-232 through fibre optics at speeds up to 1 Mbaud. A Java software, with an intuitive graphical user interface, for controlling and monitoring the sub-system was developed and installed in a hub computer. In order to allow operators to perform these tasks remotely besides locally, this was integrated in the FireSignal system. Taking advantage of FireSignal features, it was possible to provide the users with, not only the same functionalities of the local application but also a similar user interface. An independent FireSignal Java node bridges the central server and the control application. This design makes possible to easily reuse the node for other subsystems or integrate the vacuum slow control in the other CODAC systems. This document is composed of an abstract and a poster. (authors)

Vesicle fusion with bilayer lipid membrane controlled by electrostatic interaction

Directory of Open Access Journals (Sweden)

Azusa Oshima

2017-09-01

Full Text Available The fusion of proteoliposomes is a promising approach for incorporating membrane proteins in artificial lipid membranes. In this study, we employed an electrostatic interaction between vesicles and supported bilayer lipid membranes (s-BLMs to control the fusion process. We combined large unilamellar vesicles (LUVs containing anionic lipids, which we used instead of proteoliposomes, and s-BLMs containing cationic lipids to control electrostatic interaction. Anionic LUVs were never adsorbed or ruptured on the SiO2 substrate with a slight negative charge, and selectively fused with cationic s-BLMs. The LUVs can be fused effectively to the target position. Furthermore, as the vesicle fusion proceeds and some of the positive charges are neutralized, the attractive interaction weakens and finally the vesicle fusion saturates. In other words, we can control the number of LUVs fused with s-BLMs by controlling the concentration of the cationic lipids in the s-BLMs. The fluidity of the s-BLMs after vesicle fusion was confirmed to be sufficiently high. This indicates that the LUVs attached to the s-BLMs were almost completely fused, and there were few intermediate state vesicles in the fusion process. We could control the position and amount of vesicle fusion with the s-BLMs by employing an electrostatic interaction.

Genetically Controlled Fusion, Exocytosis and Fission of Artificial Vesicles

DEFF Research Database (Denmark)

Bönzli, Eva; Hadorn, Maik; De Lucrezia, Davide

if a special class of viral proteins, termed fusogenic peptides, were added to the external medium. In the present work, we intend to develop genetically controlled fusion, fission and exocytosis of vesicles by the synthesis of peptides within vesicles. First, we enclosed synthesized peptides in vesicles...... to induce in a next step fusion of adjacent vesicles, fission and exocytosis of nested vesicles. Second, we will replace the peptides by an enclosed cell-free expression system to internally synthesize fusion peptides. To control the gene expression, different mechanisms are available, e.g. addition...... fusion, fission and exocytosis....

Plasma Physics and Controlled Nuclear Fusion Research 1971. Vol. III. Proceedings of the Fourth International Conference on Plasma Physics and Controlled Nuclear Fusion Research

International Nuclear Information System (INIS)

1971-01-01

The ultimate goal of controlled nuclear fusion research is to make a new energy source available to mankind, a source that will be virtually unlimited and that gives promise of being environmentally cleaner than the sources currently exploited. This goal has stimulated research in plasma physics over the past two decades, leading to significant advances in the understanding of matter in its most common state as well as to progress in the confinement and heating of plasma. An indication of this progress is that in several countries considerable effort is being devoted to design studies of fusion reactors and to the technological problems that will be encountered in realizing these reactors. This range of research, from plasma physics to fusion reactor engineering, is shown in the present three-volume publication of the Proceedings of the Fourth Conference on Plasma Physics and Controlled Nuclear Fusion Research. The Conference was sponsored by the International Atomic Energy Agency and was held in Madison, Wisconsin, USA from 17 to 23 June 1971. The enthusiastic co-operation of the University of Wisconsin and of the United States Atomic Energy Commission in the organization of the Conference is gratefully acknowledged. The Conference was attended by over 500 scientists from 24 countries and 3 international organizations, and 143 papers were presented. These papers are published here in the original language; English translations of the Russian papers will be published in a Special Supplement to the journal Nuclear Fusion. The series of conferences on Plasma Physics and Controlled Nuclear Fusion Research has become a major international forum for the presentation and discussion of results in this important and challenging field. In addition to sponsoring these conferences, the International Atomic Energy Agency supports controlled nuclear fusion research by publishing the journal Nuclear Fusion, and has recently established an International Fusion Research Council

Control of tritium permeation through fusion reactor strucural materials

International Nuclear Information System (INIS)

Maroni, V.A.

1978-01-01

The intention of this paper is to provide a brief synopsis of the status of understanding and technology pertaining to the dissolution and permeation of tritium in fusion reactor materials. The following sections of this paper attempt to develop a simple perspective for understanding the consequences of these phenomena and the nature of the technical methodology being contemplated to control their impact on fusion reactor operation. Considered in order are: (1) the occurrence of tritium in the fusion fuel cycle, (2) a set of tentative criteria to guide the analysis of tritium containment and control strategies, (3) the basic mechanisms by which tritium may be released from a fusion plant, and (4) the methods currently under development to control the permeation-related release mechanisms. To provide background and support for these considerations, existing solubility and permeation data for the hydrogen isotopes are compared and correlated under conditions to be expected in fusion reactor systems

Information fusion in signal and image processing major probabilistic and non-probabilistic numerical approaches

CERN Document Server

Bloch, Isabelle

2010-01-01

The area of information fusion has grown considerably during the last few years, leading to a rapid and impressive evolution. In such fast-moving times, it is important to take stock of the changes that have occurred. As such, this books offers an overview of the general principles and specificities of information fusion in signal and image processing, as well as covering the main numerical methods (probabilistic approaches, fuzzy sets and possibility theory and belief functions).

Large-scale cryopumping for controlled fusion

International Nuclear Information System (INIS)

Pittenger, L.C.

1977-01-01

Vacuum pumping by freezing out or otherwise immobilizing the pumped gas is an old concept. In several plasma physics experiments for controlled fusion research, cryopumping has been used to provide clean, ultrahigh vacua. Present day fusion research devices, which rely almost universally upon neutral beams for heating, are high gas throughput systems, the pumping of which is best accomplished by cryopumping in the high mass-flow, moderate-to-high vacuum regime. Cryopumping systems have been developed for neutral beam injection systems on several fusion experiments (HVTS, TFTR) and are being developed for the overall pumping of a large, high-throughput mirror containment experiment (MFTF). In operation, these large cryopumps will require periodic defrosting, some schemes for which are discussed, along with other operational considerations. The development of cryopumps for fusion reactors is begun with the TFTR and MFTF systems. Likely paths for necessary further development for power-producing reactors are also discussed

Large-scale cryopumping for controlled fusion

Energy Technology Data Exchange (ETDEWEB)

Pittenger, L.C.

1977-07-25

Vacuum pumping by freezing out or otherwise immobilizing the pumped gas is an old concept. In several plasma physics experiments for controlled fusion research, cryopumping has been used to provide clean, ultrahigh vacua. Present day fusion research devices, which rely almost universally upon neutral beams for heating, are high gas throughput systems, the pumping of which is best accomplished by cryopumping in the high mass-flow, moderate-to-high vacuum regime. Cryopumping systems have been developed for neutral beam injection systems on several fusion experiments (HVTS, TFTR) and are being developed for the overall pumping of a large, high-throughput mirror containment experiment (MFTF). In operation, these large cryopumps will require periodic defrosting, some schemes for which are discussed, along with other operational considerations. The development of cryopumps for fusion reactors is begun with the TFTR and MFTF systems. Likely paths for necessary further development for power-producing reactors are also discussed.

Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma.

Directory of Open Access Journals (Sweden)

Ting-Lei Gu

Full Text Available Cholangiocarcinoma, also known as bile duct cancer, is the second most common primary hepatic carcinoma with a median survival of less than 2 years. The molecular mechanisms underlying the development of this disease are not clear. To survey activated tyrosine kinases signaling in cholangiocarcinoma, we employed immunoaffinity profiling coupled to mass spectrometry and identified DDR1, EPHA2, EGFR, and ROS tyrosine kinases, along with over 1,000 tyrosine phosphorylation sites from about 750 different proteins in primary cholangiocarcinoma patients. Furthermore, we confirmed the presence of ROS kinase fusions in 8.7% (2 out of 23 of cholangiocarcinoma patients. Expression of the ROS fusions in 3T3 cells confers transforming ability both in vitro and in vivo, and is responsive to its kinase inhibitor. Our data demonstrate that ROS kinase is a promising candidate for a therapeutic target and for a diagnostic molecular marker in cholangiocarcinoma. The identification of ROS tyrosine kinase fusions in cholangiocarcinoma, along with the presence of other ROS kinase fusions in lung cancer and glioblastoma, suggests that a more broadly based screen for activated ROS kinase in cancer is warranted.

Computer applications in controlled fusion research

International Nuclear Information System (INIS)

Killeen, J.

1975-02-01

The role of Nuclear Engineering Education in the application of computers to controlled fusion research can be a very important one. In the near future the use of computers in the numerical modelling of fusion systems should increase substantially. A recent study group has identified five categories of computational models to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies are called for. The development and application of computer codes to implement these models is a vital step in reaching the goal of fusion power. In order to meet the needs of the fusion program the National CTR Computer Center has been established at the Lawrence Livermore Laboratory. A large central computing facility is linked to smaller computing centers at each of the major CTR laboratories by a communications network. The crucial element that is needed for success is trained personnel. The number of people with knowledge of plasma science and engineering that are trained in numerical methods and computer science is quite small, and must be increased substantially in the next few years. Nuclear Engineering departments should encourage students to enter this field and provide the necessary courses and research programs in fusion computing. (U.S.)

Computer applications in controlled fusion research

International Nuclear Information System (INIS)

Killeen, J.

1975-01-01

The application of computers to controlled thermonuclear research (CTR) is essential. In the near future the use of computers in the numerical modeling of fusion systems should increase substantially. A recent panel has identified five categories of computational models to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies is called for. The development and application of computer codes to implement these models is a vital step in reaching the goal of fusion power. To meet the needs of the fusion program the National CTR Computer Center has been established at the Lawrence Livermore Laboratory. A large central computing facility is linked to smaller computing centers at each of the major CTR Laboratories by a communication network. The crucial element needed for success is trained personnel. The number of people with knowledge of plasma science and engineering trained in numerical methods and computer science must be increased substantially in the next few years. Nuclear engineering departments should encourage students to enter this field and provide the necessary courses and research programs in fusion computing

Plasma physics and controlled fusion research during half a century

Energy Technology Data Exchange (ETDEWEB)

Lehnert, Bo

2001-06-01

A review is given on the historical development of research on plasma physics and controlled fusion. The potentialities are outlined for fusion of light atomic nuclei, with respect to the available energy resources and the environmental properties. Various approaches in the research on controlled fusion are further described, as well as the present state of investigation and future perspectives, being based on the use of a hot plasma in a fusion reactor. Special reference is given to the part of this work which has been conducted in Sweden, merely to identify its place within the general historical development. Considerable progress has been made in fusion research during the last decades. Temperatures above the limit for ignition of self-sustained fusion reactions, i.e. at more than hundred million degrees, have been reached in large experiments and under conditions where the fusion power generation is comparable to the power losses. An energy producing fusion reactor could in principle be realized already today, but it would not become technically and economically efficient when being based on the present state of art. Future international research has therefore to be conducted along broad lines, with necessary ingredients of basic investigations and new ideas.

Plasma physics and controlled fusion research during half a century

International Nuclear Information System (INIS)

Lehnert, Bo

2001-06-01

A review is given on the historical development of research on plasma physics and controlled fusion. The potentialities are outlined for fusion of light atomic nuclei, with respect to the available energy resources and the environmental properties. Various approaches in the research on controlled fusion are further described, as well as the present state of investigation and future perspectives, being based on the use of a hot plasma in a fusion reactor. Special reference is given to the part of this work which has been conducted in Sweden, merely to identify its place within the general historical development. Considerable progress has been made in fusion research during the last decades. Temperatures above the limit for ignition of self-sustained fusion reactions, i.e. at more than hundred million degrees, have been reached in large experiments and under conditions where the fusion power generation is comparable to the power losses. An energy producing fusion reactor could in principle be realized already today, but it would not become technically and economically efficient when being based on the present state of art. Future international research has therefore to be conducted along broad lines, with necessary ingredients of basic investigations and new ideas

Closed loop control of the sawtooth instability in nuclear fusion

NARCIS (Netherlands)

Witvoet, G.; Steinbuch, M.; Westerhof, E.; Doelman, N.J.; Baar, de M.R.

2010-01-01

In nuclear fusion the sawtooth instability is an important plasma phenomenon, having both positive and negative effects on the tokamak plasma. Control of its period is essential in future nuclear fusion reactors. This paper presents a control oriented model of the sawtooth instability, with current

Remote control of a fusion facility

Energy Technology Data Exchange (ETDEWEB)

Schissel, D.P. [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States)], E-mail: schissel@fusion.gat.com; Abla, G.; Humphreys, D.A.; Penaflor, B.G.; Sammuli, B.S.; Walker, M.L. [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States)

2009-06-15

Magnetic fusion experiments keep growing in size and complexity resulting in a concurrent growth in collaboration between experimental sites and laboratories worldwide. This scientific collaboration activity is strong at existing experimental sites, is a major element of machines just coming on line, and is also a thrust of experiments that will come on line in the next decade. Computer science research into enhancing the ability to scientifically participate in a fusion experiment remotely has been growing in size in an attempt to better address the needs of fusion scientists worldwide. The natural progression of this research is to examine how to move from remote scientific participation to remote hardware control. This paper examines the challenges associated with remote experimental device control and proposes a solution based on a semantic approach that defines a Gatekeeper software system that will be the only channel of interaction for incoming requests to the experimental site. The role of the Gatekeeper is to validate the identification and access privilege of the requestor and to ensure the validity of the proposed request. The Gatekeeper will be a modular system, transparent to end-users, and allow a high volume of activity.

Remote control of a fusion facility

International Nuclear Information System (INIS)

Schissel, D.P.; Abla, G.; Humphreys, D.A.; Penaflor, B.G.; Sammuli, B.S.; Walker, M.L.

2009-01-01

Magnetic fusion experiments keep growing in size and complexity resulting in a concurrent growth in collaboration between experimental sites and laboratories worldwide. This scientific collaboration activity is strong at existing experimental sites, is a major element of machines just coming on line, and is also a thrust of experiments that will come on line in the next decade. Computer science research into enhancing the ability to scientifically participate in a fusion experiment remotely has been growing in size in an attempt to better address the needs of fusion scientists worldwide. The natural progression of this research is to examine how to move from remote scientific participation to remote hardware control. This paper examines the challenges associated with remote experimental device control and proposes a solution based on a semantic approach that defines a Gatekeeper software system that will be the only channel of interaction for incoming requests to the experimental site. The role of the Gatekeeper is to validate the identification and access privilege of the requestor and to ensure the validity of the proposed request. The Gatekeeper will be a modular system, transparent to end-users, and allow a high volume of activity.

The use of industrial type control and monitoring components for a large fusion experiment

International Nuclear Information System (INIS)

Hemming, O.N.; Manduchi, G.; Luchetta, A.; Schmidt, V.; Vitturi, S.

1994-01-01

RFX is one of the large nuclear fusion experiments within the framework of the co-ordinated nuclear fusion research programme of the European Community. During the control system design phase in 1986, the increase in power and flexibility of industrial type programmable controllers lead to the decision for a complete physical split of control, monitoring and data acquisition functions according to speed requirements, allowing the exploitation of the relative advantages of both CAMAC and programmable controllers. The 'slow' control and monitoring functions (for about 4000 digital and 200 analog I/O signals with scanning times of similar 1 second) have been implemented using a series of networked industrial PLCs and personal computers. This has allowed us to choose from a wide range of off-the-shelf hardware and software components for the plant interface and to utilize specialized expertise from the industrial field for the application software implementation. The paper gives the expectations and results gained from this design choice and how it has influenced the decisions for the evolution of the system over the next few years with the utilization of new industrial hardware components. Details are also given regarding the system integration (via the Ethernet network) with the VAX-based CAMAC frontend fast control and data-acquisition system. ((orig.))

Atomic and molecular physics of controlled thermonuclear fusion

International Nuclear Information System (INIS)

Joachain, C.J.; Post, D.E.

1983-01-01

This book attempts to provide a comprehensive introduction to the atomic and molecular physics of controlled thermonuclear fusion, and also a self-contained source from which to start a systematic study of the field. Presents an overview of fusion energy research, general principles of magnetic confinement, and general principles of inertial confinement. Discusses the calculation and measurement of atomic and molecular processes relevant to fusion, and the atomic and molecular physics of controlled thermonuclear research devices. Topics include recent progress in theoretical methods for atomic collisions; current theoretical techniques for electron-atom and electronion scattering; experimental aspects of electron impact ionization and excitation of positive ions; the theory of charge exchange and ionization by heavy particles; experiments on electron capture and ionization by multiply charged ions; Rydberg states; atomic and molecular processes in high temperature, low-density magnetically confined plasmas; atomic processes in high-density plasmas; the plasma boundary region and the role of atomic and molecular processes; neutral particle beam production and injection; spectroscopic plasma diagnostics; and particle diagnostics for magnetic fusion experiments

Gearbox fault diagnosis based on deep random forest fusion of acoustic and vibratory signals

Science.gov (United States)

Li, Chuan; Sanchez, René-Vinicio; Zurita, Grover; Cerrada, Mariela; Cabrera, Diego; Vásquez, Rafael E.

2016-08-01

Fault diagnosis is an effective tool to guarantee safe operations in gearboxes. Acoustic and vibratory measurements in such mechanical devices are all sensitive to the existence of faults. This work addresses the use of a deep random forest fusion (DRFF) technique to improve fault diagnosis performance for gearboxes by using measurements of an acoustic emission (AE) sensor and an accelerometer that are used for monitoring the gearbox condition simultaneously. The statistical parameters of the wavelet packet transform (WPT) are first produced from the AE signal and the vibratory signal, respectively. Two deep Boltzmann machines (DBMs) are then developed for deep representations of the WPT statistical parameters. A random forest is finally suggested to fuse the outputs of the two DBMs as the integrated DRFF model. The proposed DRFF technique is evaluated using gearbox fault diagnosis experiments under different operational conditions, and achieves 97.68% of the classification rate for 11 different condition patterns. Compared to other peer algorithms, the addressed method exhibits the best performance. The results indicate that the deep learning fusion of acoustic and vibratory signals may improve fault diagnosis capabilities for gearboxes.

Applications of intelligent-measurement systems in controlled-fusion research

International Nuclear Information System (INIS)

Owen, E.W.; Shimer, D.W.; Lindquist, W.B.; Peterson, R.L.; Wyman, R.H.

1981-01-01

The paper describes the control and instrumentation for the Mirror Fusion Test Facility at the Lawrence Livermore National Laboratory, California, USA. This large-scale scientific experiment in controlled thermonuclear fusion, which is currently being expanded, originally had 3000 devices to control and 7000 sensors to monitor. A hierarchical computer control system, is used with nine minicomputers forming the supervisory system. There are approximately 55 local control and instrumentation microcomputers. In addition, each device has its own monitoring equipment, which in some cases consists of a small computer. After describing the overall system a more detailed account is given of the control and instrumentation for two large superconducting magnets

Remotely controlled fusion of selected vesicles and living cells: a key issue review

Science.gov (United States)

Bahadori, Azra; Moreno-Pescador, Guillermo; Oddershede, Lene B.; Bendix, Poul M.

2018-03-01

Remote control over fusion of single cells and vesicles has a great potential in biological and chemical research allowing both transfer of genetic material between cells and transfer of molecular content between vesicles. Membrane fusion is a critical process in biology that facilitates molecular transport and mixing of cellular cytoplasms with potential formation of hybrid cells. Cells precisely regulate internal membrane fusions with the aid of specialized fusion complexes that physically provide the energy necessary for mediating fusion. Physical factors like membrane curvature, tension and temperature, affect biological membrane fusion by lowering the associated energy barrier. This has inspired the development of physical approaches to harness the fusion process at a single cell level by using remotely controlled electromagnetic fields to trigger membrane fusion. Here, we critically review various approaches, based on lasers or electric pulses, to control fusion between individual cells or between individual lipid vesicles and discuss their potential and limitations for present and future applications within biochemistry, biology and soft matter.

Controlled nuclear fusion. Theoretical and technical-physical aspects

International Nuclear Information System (INIS)

Donne, T.; Oomens, N.

1995-01-01

It is stated that the realization of controlled fusion is not only a matter of solving technical problems. Also theoretical research in the field of plasma physics is required. A brief state-of-the-art is given of theoretical and technical-physical aspects of nuclear fusion. Attention is paid to magnetic confinement, the importance of theoretical research, plasma heating, plasma diagnostics, and the control of plasma transport. Throughout the article special attention is paid to the International Thermonuclear Experimental Reactor (ITER) project. 5 figs., 1 tab., 3 refs

Laser Fusion: status, future, and tritium control

International Nuclear Information System (INIS)

Coyle, P.E.

1978-11-01

At Livermore the 10 kJ, 20 to 30 TW Shiva facility is now operational and producing regular new fusion results. Design work has begun on a 200 to 300 TW laser designed to carry the program through the first breakeven demonstration experiments in the mid-1980's. Confidence in reaching this goal is based on the significant progress we have made in state-of-the-art, high-power Nd:glass laser technology, in experimental laser fusion and laser plasma interaction physics, and in theoretical and analytical computer codes which reliably model and predict experimental results. For all of these experiments, a variety of fusion targets are being fabricated in the laboratory, and the control and handling of tritium is now a regular and routine part of ongoing inertial fusion experiments. Target design with gains of about 1000 have been studied and the means to mass produce such pellets at low cost are also being developed

Gene expression profiling of low-grade endometrial stromal sarcoma indicates fusion protein-mediated activation of the Wnt signaling pathway.

Science.gov (United States)

Przybyl, Joanna; Kidzinski, Lukasz; Hastie, Trevor; Debiec-Rychter, Maria; Nusse, Roel; van de Rijn, Matt

2018-05-01

Low-grade endometrial stromal sarcomas (LGESS) harbor chromosomal translocations that affect proteins associated with chromatin remodeling Polycomb Repressive Complex 2 (PRC2), including SUZ12, PHF1 and EPC1. Roughly half of LGESS also demonstrate nuclear accumulation of β-catenin, which is a hallmark of Wnt signaling activation. However, the targets affected by the fusion proteins and the role of Wnt signaling in the pathogenesis of these tumors remain largely unknown. Here we report the results of a meta-analysis of three independent gene expression profiling studies on LGESS and immunohistochemical evaluation of nuclear expression of β-catenin and Lef1 in 112 uterine sarcoma specimens obtained from 20 LGESS and 89 LMS patients. Our results demonstrate that 143 out of 310 genes overexpressed in LGESS are known to be directly regulated by SUZ12. In addition, our gene expression meta-analysis shows activation of multiple genes implicated in Wnt signaling. We further emphasize the role of the Wnt signaling pathway by demonstrating concordant nuclear expression of β-catenin and Lef1 in 7/16 LGESS. Based on our findings, we suggest that LGESS-specific fusion proteins disrupt the repressive function of the PRC2 complex similar to the mechanism seen in synovial sarcoma, where the SS18-SSX fusion proteins disrupt the mSWI/SNF (BAF) chromatin remodeling complex. We propose that these fusion proteins in LGESS contribute to overexpression of Wnt ligands with subsequent activation of Wnt signaling pathway and formation of an active β-catenin/Lef1 transcriptional complex. These observations could lead to novel therapeutic approaches that focus on the Wnt pathway in LGESS. Copyright © 2018 Elsevier Inc. All rights reserved.

Controlled fusion and plasma physics

International Nuclear Information System (INIS)

1994-07-01

40 papers are presented at this 21. conference on controlled fusion and plasma physics (JET). Titles are: effects of sawtooth crashes on beams ions and fusion product tritons; beta limits in H-modes and VH-modes; impurity induced neutralization of MeV energy protons in JET plasmas; lost α particle diagnostic for high-yield D-T fusion plasmas; 15-MeV proton emission from ICRF-heated plasmas; pulse compression radar reflectometry for density measurements; gamma-ray emission profile measurements during ICRH discharges; the new JET phase ICRH array; simulation of triton burn-up; parametric dependencies of JET electron temperature profiles; detached divertor plasmas; excitation of global Alfven Eigenmodes by RF heating; mechanisms of toroidal rotation; effect of shear in the radial electric field on confinement; plasma transport properties at the L-H transition; numerical study of plasma detachment conditions in JET divertor plasmas; the SOL width and the MHD interchange instability; non linear magnetic reconnection in low collisionality plasmas; topology and slowing down of high energy ion orbits; sawtooth crashes at high beta; fusion performances and alpha heating in future JET D-T plasmas; a stable route to high-beta plasmas with non-monotonic q-profiles; theory of propagation of changes to confinement; spatial distribution of gamma emissivity and fast ions during ICRF heating; multi-camera soft X-ray diagnostic; radiation phenomena and particle fluxes in the X-event; local measurement of transport parameters for laser injected trace impurities; impurity transport of high performance discharges; negative snakes and negative shear; neural-network charge exchange analysis; ion temperature anisotropy in helium neutral beam fuelling; impurity line emission due to thermal charge exchange in edge plasmas; control of convection by fuelling and pumping; VH mode accessibility and global H-mode properties; ion cyclotron emission by spontaneous emission; LHCD/ICRH synergy

The development of controlled nuclear fusion

International Nuclear Information System (INIS)

Pease, R.S.

1978-01-01

The high temperature conditions needed in a controlled nuclear fusion reactor are now being approached in experiments using magnetic fields to confine and isolate the plasma, especially in systems of the tokamak type. The underlying reasons for the successes are discussed and it is concluded that the remaining advances needed in temperature and thermal insulation may well be achieved in new large tokamak experiments now under construction. Comparable progress is being made also in inertial confinement systems; key experiments on achieving the required super-high densities with high-powered pulsed laser systems are about to commence. To achieve fusion reactors will require the combination of three major disciplines: plasma physics, electromechanical engineering and nuclear engineering. Proposals have been made for an international study group to be set up under the IAEA auspices to consider technical objectives and the nature of the next large fusion device which could be constructed internationally, and in which this synthesis could be attempted. (author)

Signalling and the control of skeletal muscle size

International Nuclear Information System (INIS)

Otto, Anthony; Patel, Ketan

2010-01-01

Skeletal muscle is highly adaptive to environmental stimuli and can alter its mass accordingly. This tissue is almost unique in that it can increase its size through two distinct mechanisms. It can grow through a cellular process mediated by cell fusion, or it can increase its size simply by increasing its protein content. Understanding how these processes are regulated is crucial for the development of potential therapies against debilitating skeletal muscle wasting diseases. Two key signalling molecules, Insulin like Growth Factor (IGF) and GDF-8/myostatin, have emerged in recent years to be potent regulators of skeletal muscle size. In this review we bring together recent data highlighting the important and novel aspects of both molecules and their signalling pathways, culminating in a discussion of the cellular and tissue phenotypic outcomes of their stimulation or antagonism. We emphasise the complex regulatory mechanisms and discuss the temporal and spatial differences that control their action, understanding of which is crucial to further their use as potential therapeutic targets.

Signalling and the control of skeletal muscle size

Energy Technology Data Exchange (ETDEWEB)

Otto, Anthony [School of Biological Sciences, Hopkins Building, University of Reading, Whiteknights Campus, Reading, Berkshire, RG6 6UB (United Kingdom); Patel, Ketan, E-mail: ketan.patel@reading.ac.uk [School of Biological Sciences, Hopkins Building, University of Reading, Whiteknights Campus, Reading, Berkshire, RG6 6UB (United Kingdom)

2010-11-01

Skeletal muscle is highly adaptive to environmental stimuli and can alter its mass accordingly. This tissue is almost unique in that it can increase its size through two distinct mechanisms. It can grow through a cellular process mediated by cell fusion, or it can increase its size simply by increasing its protein content. Understanding how these processes are regulated is crucial for the development of potential therapies against debilitating skeletal muscle wasting diseases. Two key signalling molecules, Insulin like Growth Factor (IGF) and GDF-8/myostatin, have emerged in recent years to be potent regulators of skeletal muscle size. In this review we bring together recent data highlighting the important and novel aspects of both molecules and their signalling pathways, culminating in a discussion of the cellular and tissue phenotypic outcomes of their stimulation or antagonism. We emphasise the complex regulatory mechanisms and discuss the temporal and spatial differences that control their action, understanding of which is crucial to further their use as potential therapeutic targets.

Controlled Nuclear Fusion.

Science.gov (United States)

Glasstone, Samuel

This publication is one of a series of information booklets for the general public published by The United States Atomic Energy Commission. Among the topics discussed are: Importance of Fusion Energy; Conditions for Nuclear Fusion; Thermonuclear Reactions in Plasmas; Plasma Confinement by Magnetic Fields; Experiments With Plasmas; High-Temperature…

Plasma physics and controlled nuclear fusion research 1988. V.3

International Nuclear Information System (INIS)

1989-01-01

Volume 3 of the proceedings of the twelfth international conference on plasma physics and controlled nuclear fusion, held in Nice, France, 12-19 October, 1988, contains papers presented on inertial fusion. Direct and indirect laser implosion experiments, programs of laser construction, computer modelling of implosions and resulting plasmas, and light ion beam fusion experiments are discussed. Refs, figs and tabs

Signal processing and control challenges for smart vehicles

Science.gov (United States)

Zhang, Hui; Braun, Simon G.

2017-03-01

Smart phones have changed not only the mobile phone market but also our society during the past few years. Could the next potential intelligent device may be the vehicle? Judging by the visibility, in all media, of the numerous attempts to develop autonomous vehicles, this is certainly one of the logical outcomes. Smart vehicles would be equipped with an advanced operating system such that the vehicles could communicate with others, optimize the operation to reduce fuel consumption and emissions, enhance safety, or even become self-driving. These combined new features of vehicles require instrumentation and hardware developments, fast signal processing/fusion, decision making and online optimization. Meanwhile, the inevitable increasing system complexity would certainly challenges the control unit design.

Data fusion of ultrasound and GPR signals for analysis of historic walls

International Nuclear Information System (INIS)

Salazar, A; Gosalbez, J; Safont, G; Vergara, L

2012-01-01

This paper presents an application of ultrasounds and ground-penetrating radar (GPR) for analysis of historic walls. The objectives are to characterize the deformation of a historic wall under different levels of load weights and to obtain an enhanced image of the wall. A new method that fuses data from ultrasound and GPR traces is proposed which is based on order statistics digital filters. Application results are presented for non destructive testing (NDT) of two replicates of historic ashlars' masonry walls: the first one homogeneous and the second one containing controlled defects such as cracks and nooks. The walls are measured separately using ultrasounds and GPR at different load steps. Time and frequency parameters extracted from the signals and different B-Scans for each of the NDT techniques are obtained. After this, a new fused representation is obtained, which results demonstrate the improvement of characterization and defect detection in historic walls using data fusion.

Controlled thermonuclear fusion

CERN Document Server

Bobin, Jean Louis

2014-01-01

The book is a presentation of the basic principles and main achievements in the field of nuclear fusion. It encompasses both magnetic and inertial confinements plus a few exotic mechanisms for nuclear fusion. The state-of-the-art regarding thermonuclear reactions, hot plasmas, tokamaks, laser-driven compression and future reactors is given.

Controlled nuclear fusion, a challenging task with a big payoff

International Nuclear Information System (INIS)

Noterdaeme, Jean-Marie

2003-01-01

Controlled thermonuclear fusion carries the promise of providing the world with a new source of energy, the same energy that powers the stars. Research in this area has progressed steadily for several decades now, and is ready to move into a new phase. The probability is high that a new international experimental machine (ITER) which will prove the scientific and technological feasibility of fusion energy, will be built. This paper introduces nuclear fusion for people familiar with the fission process. It starts from the basic principles common to fusion and fission. It moves on to point out the differences, explains the reasons for those differences and the consequences. Controlled thermonuclear fusion can be obtained in several ways, which have led to different research lines. One line, on which this talk focuses, is by confining the reacting particles with magnetic fields. Another, which is the subject of a different talk, relies on the inertia of the particles to create the conditions necessary for fusion. The progress of the magnetic confinement research is shown, with examples of major hurdles, which have occurred and have been overcome. Recent results, which make us optimistic that the next machine can prove the feasibility of fusion energy, are highlighted. The talk also addresses the challenges that remain before us, and suggests that the promise of fusion energy opens up new perspectives and opportunities for the development and the use of fission energy. (author)

Genetically controlled fusion, exocytosis and fission of artificial vesicles-a roadmap

DEFF Research Database (Denmark)

Bönzli, Eva; Hadorn, Maik; de Lucrezia, Davide

2011-01-01

were shown to fuse if a special class of viral proteins, termed fusogenic peptides, were added to the external medium (Nomura et al. 2004). In the present work, we intend to develop genetically controlled fusion, fission and exocytosis of vesicles by the synthesis of peptides within vesicles. First, we...... enclosed synthesized peptides in vesicles to induce in a next step fusion of adjacent vesicles, fission and exocytosis of nested vesicles. Second, we will replace the peptides by an enclosed cell-free expression system to internally synthesize fusion peptides. To control the gene expression, different...

Status report on controlled nuclear fusion as a source of hydrogen energy

International Nuclear Information System (INIS)

Powell, J.

1975-01-01

The present status of controlled fusion research is reviewed. Possible future reseach is also described. Tokamak systems using both fusion and fissionable fuels are discussed. Various aspects of hydrogen production by fusion reactors are described according to cost and economics. auth)

Towards a new generation of control and data acquisition systems for thermonuclear fusion research

International Nuclear Information System (INIS)

Van Haren, P.C.

1993-01-01

Because of the complexity of thermonuclear fusion test reactors, control systems are indispensable. The physical properties of the reactor medium, i.e. the plasma, are still not well understood. Therefore, many diagnostic techniques are applied to investigate the plasma and to discover its properties. As a consequence, data acquisition systems play an important role in thermonuclear fusion research. This thesis reports on three projects that were carried out in the field of control and data acquisition. The target experiment is the Rijnhuizen Tokamak Project (RTP), a medium-sized experiment dedicated to studies of transport in the reactor medium. One of the projects is aimed at the development of a new Plasma Position and Current Control feedback System (PPCCS). This system evaluates signals of a large (about 20) number of sensors, computes the actual state of the plasma from these signals and generates command signals for the power supplies that govern the plasma position. The most ambitious project described in this thesis is the development of a data acquisition system, called TRAMP (Transient Recorders and Amoeba Multi Processor), that aims to be a testbed for smart data acquisition strategies. TRAMP attempts to acquire and store temporarily all possible data at a high sampling frequency from a single RTP pulse, and accommodates for a resampling in software prior to transferring the data to a mass storage facility. The software resampling frequency can be tuned by analysis of the acquired data and, in that way, only interesting data will be stored. In the course of the development of both the above-mentioned systems it turned out that the existing database format applied for managing experimental data provided many hurdles in the realization of efficient solutions. Consequently, a new database format was developed together with software to deal with it. This new database, called DOM4 (Data Organization and Management), is now applied at all data acquisition

Time-frequency analysis of non-stationary fusion plasma signals using an improved Hilbert-Huang transform

International Nuclear Information System (INIS)

Liu, Yangqing; Tan, Yi; Xie, Huiqiao; Wang, Wenhao; Gao, Zhe

2014-01-01

An improved Hilbert-Huang transform method is developed to the time-frequency analysis of non-stationary signals in tokamak plasmas. Maximal overlap discrete wavelet packet transform rather than wavelet packet transform is proposed as a preprocessor to decompose a signal into various narrow-band components. Then, a correlation coefficient based selection method is utilized to eliminate the irrelevant intrinsic mode functions obtained from empirical mode decomposition of those narrow-band components. Subsequently, a time varying vector autoregressive moving average model instead of Hilbert spectral analysis is performed to compute the Hilbert spectrum, i.e., a three-dimensional time-frequency distribution of the signal. The feasibility and effectiveness of the improved Hilbert-Huang transform method is demonstrated by analyzing a non-stationary simulated signal and actual experimental signals in fusion plasmas

Towards brain-activity-controlled information retrieval: Decoding image relevance from MEG signals.

Science.gov (United States)

Kauppi, Jukka-Pekka; Kandemir, Melih; Saarinen, Veli-Matti; Hirvenkari, Lotta; Parkkonen, Lauri; Klami, Arto; Hari, Riitta; Kaski, Samuel

2015-05-15

We hypothesize that brain activity can be used to control future information retrieval systems. To this end, we conducted a feasibility study on predicting the relevance of visual objects from brain activity. We analyze both magnetoencephalographic (MEG) and gaze signals from nine subjects who were viewing image collages, a subset of which was relevant to a predetermined task. We report three findings: i) the relevance of an image a subject looks at can be decoded from MEG signals with performance significantly better than chance, ii) fusion of gaze-based and MEG-based classifiers significantly improves the prediction performance compared to using either signal alone, and iii) non-linear classification of the MEG signals using Gaussian process classifiers outperforms linear classification. These findings break new ground for building brain-activity-based interactive image retrieval systems, as well as for systems utilizing feedback both from brain activity and eye movements. Copyright © 2015 Elsevier Inc. All rights reserved.

Information Fusion-Based Optimal Attitude Control for an Alterable Thrust Direction Unmanned Aerial Vehicle

Directory of Open Access Journals (Sweden)

Ziyang Zhen

2013-01-01

Full Text Available Attitude control is the inner-loop and the most important part of the automatic flight control system of an unmanned aerial vehicle (UAV. The information fusion-based optimal control method is applied in a UAV flight control system in this work. Firstly, a nonlinear model of alterable thrust direction UAV (ATD-UAV is established and linearized for controller design. The longitudinal controller and lateral controller are respectively designed based on information fusion-based optimal control, and then the information fusion flight control system is built up. Finally, the simulation of a nonlinear model described as ATD-UAV is carried out, the results of which show the superiority of the information fusion-based control strategy when compared to the single-loop design method. We also show that the ATD technique improves the anti-disturbance capacity of the UAV.

Rasiowa completion versus Keisler saturation: Towards a pragmatics of infinite fusion

Energy Technology Data Exchange (ETDEWEB)

Tomasik, J.A. [Univ. of Clermont (France)

1996-12-31

The goal of this survey note is to make a step towards a semiotical approach to the control of Sensor Data Fusion systems. We try to adapt infinitistic methods of Rasiowa and Keisler as prototypes of a many-one pragmatics for the control of SDF in order to provide a faithful system - semantical or/and syntactical - adequate for simultaneous interpretation of signals received through several sensors. Intuitively, it is clear that the amount of the information captured during the fusion process depends strongly on the fusion itself. Nevertheless we can find (c.f. works of Kokar`s group) the following implicit heuristic in semiotical investigations on Sensory Data Fusion Z`s accepted.

FireSignal application Node for subsystem control

Czech Academy of Sciences Publication Activity Database

Duarte, A.S.; Santos, B.; Pereira, T.; Carvalho, B.B.; Fernandes, H.; Neto, A.; Janky, Filip; Cahyna, Pavel; Písačka, Jan; Hron, Martin

2010-01-01

Roč. 85, 3-4 (2010), s. 496-499 ISSN 0920-3796. [IAEA Technical Meeting on Control , Data Acquisition and Remote Participation for Fusion Research/7th./. Aix – en – Provence, 15.06.2009-19.06.2009] Institutional research plan: CEZ:AV0Z20430508 Keywords : Subsystems * CODAC * FireSignal * Java * Remote operation Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.143, year: 2010 http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6V3C-4YYGPR8-4&_user=6542793&_coverDate=07%2F31%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000070123&_version=1&_urlVersion=0&_userid=6542793&md5=899631b6e2f4d05b21b04bde3cfb8e65&searchtype=a

FireSignal - Data Acquisition and Control System Software

International Nuclear Information System (INIS)

Neto, A.; Fernandes, H.; Duarte, A.; Carvalho, B.; Sousa, J.; Valcarcel, D.; Varandas, C.; Hron, M.

2006-01-01

Control of fusion devices requires good, non-ambiguous, easy to use user-interfaces to configure hardware devices. To solve this problem a highly generic system for data control and acquisition has been developed. Among the main features it allows remote hardware configuration, shot launching, data sharing between connected users and experiment monitoring. The system is fully distributed: the hardware driver nodes, clients and server are completely independent from each other and might be running in different operating systems and programmed in different languages. All the communication is provided through the Common Object Request Broker Architecture (CORBA) protocol. FireSignal was designed from the beginning to be as independent as possible from any kind of constraints as it's a plugin based system. Database, data viewers and the security system are some examples of what can easily be changed and adapted to the target machine's needs. All hardware is described in eXtendend Markup Language (XML) and from this information the FireSignal client application can build automatically Graphical User Interfaces (GUI) and validate the user's parameter configuration. Any type of hardware can be integrated in the system as long as it is described in XML and the respective driver is developed. Any modern programming language can be used to develop these drivers, and currently we use Python and Java generic drivers. All data storage and indexing is time stamped event-based s. Nodes are responsible for tagging the acquired samples with the absolute time stamps and to react to machine events. FireSignal is currently being used to control the ISTTOK/PT and CASTOR/CZ tokamaks. (author)

Thermonuclear controlled fusion: international cooperation

International Nuclear Information System (INIS)

Conscience, J.-F.

2001-01-01

This report summarizes the current worldwide status of research in the field of thermonuclear controlled fusion as well as the international research programme planed for the next decades. The two main projects will be the ITER facility (International Thermonuclear Experimental Reactor) that should produce 10 times more energy than the energy injected, and the IFMIF (International Fusion Materials Irradiation Facility) designed to study the reactions of materials under intense neutron fluxes. The future of the pioneering JET facility (Joint European Torus) is also discussed. The engagement of the various countries (USA, Japan, Germany, Russian Federation and Canada) and international organisations (EURATOM and IEA) in terms of investment and research is described. Switzerland is involved in this program through an agreement with EURATOM and is mainly dedicated to experimental studies with the TCV machine in Lausanne and numerical studies of plasma configurations. It will participate to the development of the microwave plasma heating system for the ITER machine

Dispersion interferometer for controlled fusion devices

International Nuclear Information System (INIS)

Drachev, V.P.; Krasnikov, Yu.I.; Bagryansky, P.A.

1992-01-01

A common feature in interferometry is the presence of two independent optical channels. Since wave phase in a medium depends on the geometrical path, polarization and radiation frequency, respectively, one can distinguish three types of interferometric schemes when the channels are geometrically separated, or separation occurs in polarizations or radiation frequencies. We have developed a measurement scheme based on a dispersion interferometer (DI) for plasma diagnostics in the experiments on controlled fusion. DI optical channels have the same geometrical path and are separated in radiation frequency. Use of a common optical path causes the main advantage of the DI technique - low sensitivity to vibrations of optical elements. The use of the DI technique for diagnostics of a laser spark in air and of arc discharges has shown its essential advantages as compared to classical interferometers. Interest in the DI technique from the viewpoint of its application in controlled fusion devices is determined also generated by the possibility of developing a compact multichannel interferometer not requiring a vibration isolation structure. (author) 14 refs., 3 figs

Specific expression of GFPuv-β1,3-N-acetylglucosaminyltransferase 2 fusion protein in fat body of Bombyx mori silkworm larvae using signal peptide

International Nuclear Information System (INIS)

Kato, Tatsuya; Park, Enoch Y.

2007-01-01

Bombyxin (bx) and prophenoloxidase-activating enzyme (ppae) signal peptides from Bombyx mori, their modified signal peptides, and synthetic signal peptides were investigated for the secretion of GFP uv -β1,3-N-acetylglucosaminyltransferase 2 (GGT2) fusion protein in B. mori Bm5 cells and silkworm larvae using cysteine protease deficient B. mori multiple nucleopolyhedrovirus (BmMNPV-CP - ) and its bacmid. The secretion efficiencies of all signal peptides were 15-30% in Bm5 cells and 24-30% in silkworm larvae, while that of the +16 signal peptide was 0% in Bm5 cells and 1% in silkworm larvae. The fusion protein that contained the +16 signal peptide was expressed specifically in the endoplasmic reticulum (ER) and in the fractions of cell precipitations. Ninety-four percent of total intracellular β1,3-N-acetylglucosaminyltransferase (β3GnT) activity was detected in cell precipitations following the 600, 8000, and 114,000g centrifugations. In the case of the +38 signal peptide, 60% of total intracellular activity was detected in the supernatant from the 114,000g spin, and only 1% was found in the precipitate. Our results suggest that the +16 signal peptide might be situated in the transmembrane region and not cleaved by signal peptidase in silkworm or B. mori cells. Therefore, the fusion protein connected to the +16 signal peptide stayed in the fat body of silkworm larvae with biological function, and was not secreted extracellularly

The ORNL Controlled Fusion Atomic Data Center

International Nuclear Information System (INIS)

Schultz, D.R.; Krstic, P.S.; Ownby, F.M.; Meyer, F.W.; Havener, C.C.; Bannister, M.E.; Liu, W.; Jeffery, D.J.; Stancil, P.C.

1997-01-01

The principal mission of the Controlled Fusion Atomic Data Center is the collection evaluation, and dissemination of atomic collision data relevant to fusion energy development. With the advent of the widespread use of the World Wide Web, the data center's resources are being placed on-line to facilitate their use by end-users (cf. http://www-cfadc.phy.ornl.gov/). As this development continues, initially disparate, individually compiled resources will be transformed into integrated tools for retrieving recommended data, or displaying and manipulating the information available. The data center's present capabilities, recent data production/evaluation efforts, and goals for future development are highlighted here

Surface effects in controlled thermonuclear fusion

International Nuclear Information System (INIS)

Kaminsky, M.

1975-08-01

During the operation of large size plasma facilities and future controlled thermonuclear fusion reactors the surfaces of such major components as container walls, beam limiters, diverter walls and beam-dump walls of the injector region will be exposed to particle and photon bombardment from primary plasma radiations and from secondary radiations. Such radiations can cause, for example, physical and chemical sputtering, blistering, particle- and photon-impact induced desorption, secondary electron and x-ray emission, backscattering, nuclear reactions, photo-decomposition of surface compounds, photocatalysis, and vaporization. Such effects in turn can (a) seriously damage and erode the bombarded surface and (b) release major quantities of impurities which will contaminate the plasma. The effects of some of the major surface phenomena on the operation of plasma facilities and future fusion reactors are discussed

Plasma physics for controlled fusion. 2. ed.

Energy Technology Data Exchange (ETDEWEB)

Miyamoto, Kenro

2016-08-01

This new edition presents the essential theoretical and analytical methods needed to understand the recent fusion research of tokamak and alternate approaches. The author describes magnetohydrodynamic and kinetic theories of cold and hot plasmas in detail. The book covers new important topics for fusion studies such as plasma transport by drift turbulence, which depend on the magnetic configuration and zonal flows. These are universal phenomena of microturbulence. They can modify the onset criterion for turbulent transport, instabilities driven by energetic particles as well as alpha particle generation and typical plasma models for computer simulation. The fusion research of tokamaks with various new versions of H modes are explained. The design concept of ITER, the international tokamak experimental reactor, is described for inductively driven operations as well as steady-state operations using non-inductive drives. Alternative approaches of reversed-field pinch and its relaxation process, stellator including quasi-symmetric system, open-end system of tandem mirror and inertial confinement are also explained. Newly added and updated topics in this second edition include zonal flows, various versions of H modes, and steady-state operations of tokamak, the design concept of ITER, the relaxation process of RFP, quasi-symmetric stellator, and tandem mirror. The book addresses graduate students and researchers in the field of controlled fusion.

Plasma physics for controlled fusion. 2. ed.

International Nuclear Information System (INIS)

Miyamoto, Kenro

2016-01-01

This new edition presents the essential theoretical and analytical methods needed to understand the recent fusion research of tokamak and alternate approaches. The author describes magnetohydrodynamic and kinetic theories of cold and hot plasmas in detail. The book covers new important topics for fusion studies such as plasma transport by drift turbulence, which depend on the magnetic configuration and zonal flows. These are universal phenomena of microturbulence. They can modify the onset criterion for turbulent transport, instabilities driven by energetic particles as well as alpha particle generation and typical plasma models for computer simulation. The fusion research of tokamaks with various new versions of H modes are explained. The design concept of ITER, the international tokamak experimental reactor, is described for inductively driven operations as well as steady-state operations using non-inductive drives. Alternative approaches of reversed-field pinch and its relaxation process, stellator including quasi-symmetric system, open-end system of tandem mirror and inertial confinement are also explained. Newly added and updated topics in this second edition include zonal flows, various versions of H modes, and steady-state operations of tokamak, the design concept of ITER, the relaxation process of RFP, quasi-symmetric stellator, and tandem mirror. The book addresses graduate students and researchers in the field of controlled fusion.

The Wnt/β-catenin signaling pathway tips the balance between apoptosis and reprograming of cell fusion hybrids.

Science.gov (United States)

Lluis, Frederic; Pedone, Elisa; Pepe, Stefano; Cosma, Maria Pia

2010-11-01

Cell-cell fusion contributes to cell differentiation and developmental processes. We have previously showed that activation of Wnt/β-catenin enhances somatic cell reprograming after polyethylene glycol (PEG)-mediated fusion. Here, we show that neural stem cells and ESCs can fuse spontaneously in cocultures, although with very low efficiency (about 2%), as the hybrids undergo apoptosis. In contrast, when Wnt/β-catenin signaling is activated in ESCs and leads to accumulation of low amounts of β-catenin in the nucleus, activated ESCs can reprogram somatic cells with very high efficiency after spontaneous fusion. Furthermore, we also show that different levels of β-catenin accumulation in the ESC nuclei can modulate cell proliferation, although in our experimental setting, cell proliferation does not modulate the reprograming efficiency per se. Overall, the present study provides evidence that spontaneous fusion occurs, while the survival of the reprogramed clones is strictly dependent on induction of a Wnt-mediated reprograming pathway. Copyright © 2010 AlphaMed Press.

Controlled fusion and plasma heating

International Nuclear Information System (INIS)

1990-06-01

The contributions presented in the 17th European Conference on Controlled Fusion and Plasma Heating were focused on Tore Supra investigations. The following subjects were presented: ohmic discharges, lower hybrid experiments, runaway electrons, Thomson scattering, plasma density measurements, magnetic fluctuations, polarization scattering, plasma currents, plasma fluctuation measurements, evaporation of hydrogen pellets in presence of fast electrons, ripple induced stochastic diffusion of trapped particles, tearing mode stabilization, edge effects on turbulence behavior, electron cyclotron heating, micro-tearing modes, divertors, limiters

Plasma surface interactions in controlled fusion devices

Energy Technology Data Exchange (ETDEWEB)

Ghendrih, Ph.; Becoulet, M.; Costanzo, L. [and others

2000-07-01

This report brings together all the contributions of EURATOM/CEA association to the 14. international conference on plasma surface interactions in controlled fusion devices. 24 papers are presented and they deal mainly with the ergodic divertor and the first wall of Tore-supra tokamak.

Plasma surface interactions in controlled fusion devices

International Nuclear Information System (INIS)

Ghendrih, Ph.; Becoulet, M.; Costanzo, L.

2000-07-01

This report brings together all the contributions of EURATOM/CEA association to the 14. international conference on plasma surface interactions in controlled fusion devices. 24 papers are presented and they deal mainly with the ergodic divertor and the first wall of Tore-supra tokamak

Physics of plasma-wall interactions in controlled fusion

International Nuclear Information System (INIS)

Post, D.E.; Behrisch, R.

1984-01-01

In the areas of plasma physics, atomic physics, surface physics, bulk material properties and fusion experiments and theory, the following topics are presented: the plasma sheath; plasma flow in the sheath and presheath of a scrape-off layer; probes for plasma edge diagnostics in magnetic confinement fusion devices; atomic and molecular collisions in the plasma boundary; physical sputtering of solids at ion bombardment; chemical sputtering and radiation enhanced sublimation of carbon; ion backscattering from solid surfaces; implantation, retention and release of hydrogen isotopes; surface erosion by electrical arcs; electron emission from solid surfaces;l properties of materials; plasma transport near material boundaries; plasma models for impurity control experiments; neutral particle transport; particle confinement and control in existing tokamaks; limiters and divertor plates; advanced limiters; divertor tokamak experiments; plasma wall interactions in heated plasmas; plasma-wall interactions in tandem mirror machines; and impurity control systems for reactor experiments

Particle and impurity control in toroidal fusion devices

International Nuclear Information System (INIS)

Wootton, A.J.

1986-01-01

A review of working particle and impurity control techniques used in and proposed for magnetic fusion devices is presented. The requirements of both present-day machines and envisaged fusion reactors are considered. The various techniques which have been proposed are characterized by whether they affect sources, sinks, or fluxes; in many cases a particular method or device can appear in more than one category. Examples are drawn from published results. The solutions proposed for the large devices which will be operating during the next 5 years are discussed

Sensor fusion for mobile robot navigation

International Nuclear Information System (INIS)

Kam, M.; Zhu, X.; Kalata, P.

1997-01-01

The authors review techniques for sensor fusion in robot navigation, emphasizing algorithms for self-location. These find use when the sensor suite of a mobile robot comprises several different sensors, some complementary and some redundant. Integrating the sensor readings, the robot seeks to accomplish tasks such as constructing a map of its environment, locating itself in that map, and recognizing objects that should be avoided or sought. The review describes integration techniques in two categories: low-level fusion is used for direct integration of sensory data, resulting in parameter and state estimates; high-level fusion is used for indirect integration of sensory data in hierarchical architectures, through command arbitration and integration of control signals suggested by different modules. The review provides an arsenal of tools for addressing this (rather ill-posed) problem in machine intelligence, including Kalman filtering, rule-based techniques, behavior based algorithms and approaches that borrow from information theory, Dempster-Shafer reasoning, fuzzy logic and neural networks. It points to several further-research needs, including: robustness of decision rules; simultaneous consideration of self-location, motion planning, motion control and vehicle dynamics; the effect of sensor placement and attention focusing on sensor fusion; and adaptation of techniques from biological sensor fusion

Fusion Control of Flexible Logic Control and Neural Network

Directory of Open Access Journals (Sweden)

Lihua Fu

2014-01-01

Full Text Available Based on the basic physical meaning of error E and error variety EC, this paper analyzes the logical relationship between them and uses Universal Combinatorial Operation Model in Universal Logic to describe it. Accordingly, a flexible logic control method is put forward to realize effective control on multivariable nonlinear system. In order to implement fusion control with artificial neural network, this paper proposes a new neuron model of Zero-level Universal Combinatorial Operation in Universal Logic. And the artificial neural network of flexible logic control model is implemented based on the proposed neuron model. Finally, stability control, anti-interference control of double inverted-pendulum system, and free walking of cart pendulum system on a level track are realized, showing experimentally the feasibility and validity of this method.

Information fusion under consideration of conflicting input signals

CERN Document Server

Mönks, Uwe

2017-01-01

This work proposes the multilayered information fusion system MACRO (multilayer attribute-based conflict-reducing observation) and the µBalTLCS (fuzzified balanced two-layer conflict solving) fusion algorithm to reduce the impact of conflicts on the fusion result. In addition, a sensor defect detection method, which is based on the continuous monitoring of sensor reliabilities, is presented. The performances of the contributions are shown by their evaluation in the scope of both a publicly available data set and a machine condition monitoring application under laboratory conditions. Here, the MACRO system yields the best results compared to state-of-the-art fusion mechanisms. The author Dr.-Ing. Uwe Mönks studied Electrical Engineering and Information Technology at the OWL University of Applied Sciences (Lemgo), Halmstad University (Sweden), and Aalborg University (Denmark). Since 2009 he is employed at the Institute Industrial IT (inIT) as research associate with project leading responsibilities. During th...

Optimal control theory applied to fusion plasma thermal stabilization

International Nuclear Information System (INIS)

Sager, G.; Miley, G.; Maya, I.

1985-01-01

Many authors have investigated stability characteristics and performance of various burn control schemes. The work presented here represents the first application of optimal control theory to the problem of fusion plasma thermal stabilization. The objectives of this initial investigation were to develop analysis methods, demonstrate tractability, and present some preliminary results of optimal control theory in burn control research

Signal processing, sensor fusion, and target recognition; Proceedings of the Meeting, Orlando, FL, Apr. 20-22, 1992

Science.gov (United States)

Libby, Vibeke; Kadar, Ivan

Consideration is given to a multiordered mapping technique for target prioritization, a neural network approach to multiple-target-tracking problems, a multisensor fusion algorithm for multitarget multibackground classification, deconvolutiom of multiple images of the same object, neural networks and genetic algorithms for combinatorial optimization of sensor data fusion, classification of atmospheric acoustic signals from fixed-wing aircraft, and an optics approach to sensor fusion for target recognition. Also treated are a zoom lens for automatic target recognition, a hybrid model for the analysis of radar sensors, an innovative test bed for developing and assessing air-to-air noncooperative target identification algorithms, SAR imagery scene segmentation using fractal processing, sonar feature-based bandwidth compression, laboratory experiments for a new sonar system, computational algorithms for discrete transform using fixed-size filter matrices, and pattern recognition for power systems.

Control of Internal Transport Barriers in Magnetically Confined Fusion Plasmas

Science.gov (United States)

Panta, Soma; Newman, David; Sanchez, Raul; Terry, Paul

2016-10-01

In magnetic confinement fusion devices the best performance often involves some sort of transport barriers to reduce the energy and particle flow from core to edge. Those barriers create gradients in the temperature and density profiles. If gradients in the profiles are too steep that can lead to instabilities and the system collapses. Control of these barriers is therefore an important challenge for fusion devices (burning plasmas). In this work we focus on the dynamics of internal transport barriers. Using a simple 7 field transport model, extensively used for barrier dynamics and control studies, we explore the use of RF heating to control the local gradients and therefore the growth rates and shearing rates for barrier initiation and control in self-heated fusion plasmas. Ion channel barriers can be formed in self-heated plasmas with some NBI heating but electron channel barriers are very sensitive. They can be formed in self-heated plasmas with additional auxiliary heating i.e. NBI and radio-frequency(RF). Using RF heating on both electrons and ions at proper locations, electron channel barriers along with ion channel barriers can be formed and removed demonstrating a control technique. Investigating the role of pellet injection in controlling the barriers is our next goal. Work supported by DOE Grant DE-FG02-04ER54741.

Hemi-fused structure mediates and controls fusion and fission in live cells.

Science.gov (United States)

Zhao, Wei-Dong; Hamid, Edaeni; Shin, Wonchul; Wen, Peter J; Krystofiak, Evan S; Villarreal, Seth A; Chiang, Hsueh-Cheng; Kachar, Bechara; Wu, Ling-Gang

2016-06-23

Membrane fusion and fission are vital for eukaryotic life. For three decades, it has been proposed that fusion is mediated by fusion between the proximal leaflets of two bilayers (hemi-fusion) to produce a hemi-fused structure, followed by fusion between the distal leaflets, whereas fission is via hemi-fission, which also produces a hemi-fused structure, followed by full fission. This hypothesis remained unsupported owing to the lack of observation of hemi-fusion or hemi-fission in live cells. A competing fusion hypothesis involving protein-lined pore formation has also been proposed. Here we report the observation of a hemi-fused Ω-shaped structure in live neuroendocrine chromaffin cells and pancreatic β-cells, visualized using confocal and super-resolution stimulated emission depletion microscopy. This structure is generated from fusion pore opening or closure (fission) at the plasma membrane. Unexpectedly, the transition to full fusion or fission is determined by competition between fusion and calcium/dynamin-dependent fission mechanisms, and is notably slow (seconds to tens of seconds) in a substantial fraction of the events. These results provide key missing evidence in support of the hemi-fusion and hemi-fission hypothesis in live cells, and reveal the hemi-fused intermediate as a key structure controlling fusion and fission, as fusion and fission mechanisms compete to determine the transition to fusion or fission.

FireSignal-Data acquisition and control system software

Energy Technology Data Exchange (ETDEWEB)

Neto, A. [Associacao Euratom/IST, Centro de Fusao Nuclear, Av. Rovisco Pais, P-1049-001 Lisboa (Portugal)], E-mail: andre.neto@cfn.ist.utl.pt; Fernandes, H.; Duarte, A.; Carvalho, B.B.; Sousa, J.; Valcarcel, D.F. [Associacao Euratom/IST, Centro de Fusao Nuclear, Av. Rovisco Pais, P-1049-001 Lisboa (Portugal); Hron, M. [Asociace EURATOM IPP.CR, Prague (Czech Republic); Varandas, C.A.F. [Associacao Euratom/IST, Centro de Fusao Nuclear, Av. Rovisco Pais, P-1049-001 Lisboa (Portugal)

2007-10-15

Control of fusion experiments requires non-ambiguous, easy to use, user-interfaces to configure hardware devices. With that aim, a highly generic system for data control and acquisition has been developed. Among the main features it allows remote hardware configuration, shot launching, data sharing between connected users and experiment monitoring. The system is fully distributed: the hardware driver nodes, clients and servers are completely independent from each other and might run in different operating systems and programmed in different languages. All the communication is provided through the Common Object Request Broker Architecture (CORBA) protocol. FireSignal is designed to be as independent as possible from any kind of constraints as it is a plugin based system. Database, data viewers and the security system are some examples of what can easily be changed and adapted to the target machine's needs. In this system, every hardware is described in eXtensible Markup Language (XML) and with this information Graphical User Interfaces (GUI) are automatically built and user's parameter configuration validated. Any type of hardware device can be integrated in the system as long as it is described in XML and the respective driver developed. Any modern programming language can be used to develop these drivers. Currently Python and Java generic drivers are used. Data storage and indexing is time stamp event-based. Nodes are responsible for tagging the acquired samples with the absolute time stamps and to react to machine events. FireSignal is currently being used to control the ISTTOK/PT and CASTOR/CZ tokamaks.

FireSignal-Data acquisition and control system software

International Nuclear Information System (INIS)

Neto, A.; Fernandes, H.; Duarte, A.; Carvalho, B.B.; Sousa, J.; Valcarcel, D.F.; Hron, M.; Varandas, C.A.F.

2007-01-01

Control of fusion experiments requires non-ambiguous, easy to use, user-interfaces to configure hardware devices. With that aim, a highly generic system for data control and acquisition has been developed. Among the main features it allows remote hardware configuration, shot launching, data sharing between connected users and experiment monitoring. The system is fully distributed: the hardware driver nodes, clients and servers are completely independent from each other and might run in different operating systems and programmed in different languages. All the communication is provided through the Common Object Request Broker Architecture (CORBA) protocol. FireSignal is designed to be as independent as possible from any kind of constraints as it is a plugin based system. Database, data viewers and the security system are some examples of what can easily be changed and adapted to the target machine's needs. In this system, every hardware is described in eXtensible Markup Language (XML) and with this information Graphical User Interfaces (GUI) are automatically built and user's parameter configuration validated. Any type of hardware device can be integrated in the system as long as it is described in XML and the respective driver developed. Any modern programming language can be used to develop these drivers. Currently Python and Java generic drivers are used. Data storage and indexing is time stamp event-based. Nodes are responsible for tagging the acquired samples with the absolute time stamps and to react to machine events. FireSignal is currently being used to control the ISTTOK/PT and CASTOR/CZ tokamaks

Status report on controlled thermonuclear fusion

International Nuclear Information System (INIS)

1990-01-01

The International Fusion Research Council has prepared this report on the current status of fusion, an update of its 1978 report, at the request of the Director General of the International Atomic Energy Agency. The report consists of an introductory note by the Director General, an Executive Summary and General Overview published in this document, and a series of technical reports. The background of fusion as an energy source is documented and compared with fission. The two approaches to thermonuclear fusion, magnetic confinement and inertial confinement, are discussed. The viability with respect to economic, environmental, and safety aspects is discussed. Fusion programs in the European Community, Japan, the USSR, the USA, as well as smaller programs in other countries are described. The status of fusion physics and technology is elucidated, and future directions and plans are indicated. 5 refs, 6 figs

Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway.

Science.gov (United States)

Werner, Haim; Meisel-Sharon, Shilhav; Bruchim, Ilan

2018-02-19

The insulin-like growth factor-1 receptor (IGF1R) has been identified as a potent anti-apoptotic, pro-survival tyrosine kinase-containing receptor. Overexpression of the IGF1R gene constitutes a typical feature of most human cancers. Consistent with these biological roles, cells expressing high levels of IGF1R are expected not to die, a quintessential feature of cancer cells. Tumor specific chromosomal translocations that disrupt the architecture of transcription factors are a common theme in carcinogenesis. Increasing evidence gathered over the past fifteen years demonstrate that this type of genomic rearrangements is common not only among pediatric and hematological malignancies, as classically thought, but may also provide a molecular and cytogenetic foundation for an ever-increasing portion of adult epithelial tumors. In this review article we provide evidence that the mechanism of action of oncogenic fusion proteins associated with both pediatric and adult malignancies involves transactivation of the IGF1R gene, with ensuing increases in IGF1R levels and ligand-mediated receptor phosphorylation. Disrupted transcription factors adopt the IGF1R signaling pathway and elicit their oncogenic activities via activation of this critical regulatory network. Combined targeting of oncogenic fusion proteins along with the IGF1R may constitute a promising therapeutic approach.

Controlled Fusion with Hot-ion Mode in a Degenerate Plasma

International Nuclear Information System (INIS)

S. Son and N.J. Fisch

2005-01-01

In a Fermi-degenerate plasma, the rate of electron physical processes is much reduced from the classical prediction, possibly enabling new regimes for controlled nuclear fusion, including the hot-ion mode, a regime in which the ion temperature exceeds the electron temperature. Previous calculations of these processes in dense plasmas are now corrected for partial degeneracy and relativistic effects, leading to an expanded regime of self-sustained fusion

Synchronization in a PLC/VAX-based control and data-acquisition system of a nuclear-fusion experiment

International Nuclear Information System (INIS)

Schmidt, V.; Flor, G.; Hemming, O.N.; Luchetta, A.; Manduchi, G.; Vitturi, S.

1990-01-01

This paper describes the concept and implementation details of the synchronization mechanisms used in the control and data-acquisition system of the RFX (Reversed-Field Experiment) nuclear-fusion experimental device, at present under construction in Padova, Italy, within the framework of the co-ordinated nuclear-fusion research programme of the European Communities. The system employs industrial PLCs for the 'slow' control and monitoring functions, and a VAX-based CAMAC for the 'fast' functions of trigger-signal generation and data acquisition during the experiment pulses. All subsystems communicate via Ethernet, using compatible software protocols. The operational sequence of the complete system is governed by a single state machine implemented on a PLC-based supervisor system. Equivalent 'slave' state machines are implemented on all other subsystems (PLC- and VAX-based). These state machines are synchronized by means of the exchange of messages via Ethernet. This paper deals in detail with the following components which are involved in system synchronization: The Message Exchange System which implements the system-wide exchange of short messages; the Scheduler programs which implement the state machine on the various computing nodes, and which make use of the Message Exchange System. (orig.)

Fusion Physics

Energy Technology Data Exchange (ETDEWEB)

Kikuchi, Mitsuru; Lackner, Karl; Tran, Minh Quang [eds.

2012-09-15

Recreating the energy production process of the Sun - nuclear fusion - on Earth in a controlled fashion is one of the greatest challenges of this century. If achieved at affordable costs, energy supply security would be greatly enhanced and environmental degradation from fossil fuels greatly diminished. Fusion Physics describes the last fifty years or so of physics and research in innovative technologies to achieve controlled thermonuclear fusion for energy production. The International Atomic Energy Agency (IAEA) has been involved since its establishment in 1957 in fusion research. It has been the driving force behind the biennial conferences on Plasma Physics and Controlled Thermonuclear Fusion, today known as the Fusion Energy Conference. Hosted by several Member States, this biennial conference provides a global forum for exchange of the latest achievements in fusion research against the backdrop of the requirements for a net energy producing fusion device and, eventually, a fusion power plant. The scientific and technological knowledge compiled during this series of conferences, as well as by the IAEA Nuclear Fusion journal, is immense and will surely continue to grow in the future. It has led to the establishment of the International Thermonuclear Experimental Reactor (ITER), which represents the biggest experiment in energy production ever envisaged by humankind.

Viral membrane fusion

International Nuclear Information System (INIS)

Harrison, Stephen C.

2015-01-01

Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the agents that fulfill this catalytic function. Despite a variety of molecular architectures, these proteins facilitate fusion by essentially the same generic mechanism. Stimulated by a signal associated with arrival at the cell to be infected (e.g., receptor or co-receptor binding, proton binding in an endosome), they undergo a series of conformational changes. A hydrophobic segment (a “fusion loop” or “fusion peptide”) engages the target-cell membrane and collapse of the bridging intermediate thus formed draws the two membranes (virus and cell) together. We know of three structural classes for viral fusion proteins. Structures for both pre- and postfusion conformations of illustrate the beginning and end points of a process that can be probed by single-virion measurements of fusion kinetics. - Highlights: • Viral fusion proteins overcome the high energy barrier to lipid bilayer merger. • Different molecular structures but the same catalytic mechanism. • Review describes properties of three known fusion-protein structural classes. • Single-virion fusion experiments elucidate mechanism

Viral membrane fusion

Energy Technology Data Exchange (ETDEWEB)

Harrison, Stephen C., E-mail: harrison@crystal.harvard.edu

2015-05-15

Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the agents that fulfill this catalytic function. Despite a variety of molecular architectures, these proteins facilitate fusion by essentially the same generic mechanism. Stimulated by a signal associated with arrival at the cell to be infected (e.g., receptor or co-receptor binding, proton binding in an endosome), they undergo a series of conformational changes. A hydrophobic segment (a “fusion loop” or “fusion peptide”) engages the target-cell membrane and collapse of the bridging intermediate thus formed draws the two membranes (virus and cell) together. We know of three structural classes for viral fusion proteins. Structures for both pre- and postfusion conformations of illustrate the beginning and end points of a process that can be probed by single-virion measurements of fusion kinetics. - Highlights: • Viral fusion proteins overcome the high energy barrier to lipid bilayer merger. • Different molecular structures but the same catalytic mechanism. • Review describes properties of three known fusion-protein structural classes. • Single-virion fusion experiments elucidate mechanism.

Automatic calibration and signal switching system for the particle beam fusion research data acquisition facility

Energy Technology Data Exchange (ETDEWEB)

Boyer, W.B.

1979-09-01

This report describes both the hardware and software components of an automatic calibration and signal system (Autocal) for the data acquisition system for the Sandia particle beam fusion research accelerators Hydra, Proto I, and Proto II. The Autocal hardware consists of off-the-shelf commercial equipment. The various hardware components, special modifications and overall system configuration are described. Special software has been developed to support the Autocal hardware. Software operation and maintenance are described.

Automatic calibration and signal switching system for the particle beam fusion research data acquisition facility

International Nuclear Information System (INIS)

Boyer, W.B.

1979-09-01

This report describes both the hardware and software components of an automatic calibration and signal system (Autocal) for the data acquisition system for the Sandia particle beam fusion research accelerators Hydra, Proto I, and Proto II. The Autocal hardware consists of off-the-shelf commercial equipment. The various hardware components, special modifications and overall system configuration are described. Special software has been developed to support the Autocal hardware. Software operation and maintenance are described

Brazilian programme for plasma physics and controlled thermonuclear fusion

International Nuclear Information System (INIS)

Chian, A.C.L.; Reusch, M.F.; Nascimento, I.C.; Pantuso-Sudano, J.

1992-01-01

A proposal for a National Programme of Plasma Physics and Controlled Thermonuclear Fusion in Brazil is presented, aimimg the dissemination of the researchers thought in plasma physics for the national authorities and the scientific community. (E.O.)

NATO Advanced Study Institute entitled Physics of Plasma-Wall Interactions in Controlled Fusion

CERN Document Server

Behrisch, R; Physics of plasma-wall interactions in controlled fusion

1986-01-01

Controlled thermonuclear fusion is one of the possible candidates for long term energy sources which will be indispensable for our highly technological society. However, the physics and technology of controlled fusion are extremely complex and still require a great deal of research and development before fusion can be a practical energy source. For producing energy via controlled fusion a deuterium-tritium gas has to be heated to temperatures of a few 100 Million °c corres­ ponding to about 10 keV. For net energy gain, this hot plasma has to be confined at a certain density for a certain time One pro­ mising scheme to confine such a plasma is the use of i~tense mag­ netic fields. However, the plasma diffuses out of the confining magnetic surfaces and impinges on the surrounding vessel walls which isolate the plasma from the surrounding air. Because of this plasma wall interaction, particles from the plasma are lost to the walls by implantation and are partially reemitted into the plasma. In addition, wall...

Italy, EURATOM and Early Research on Controlled Thermonuclear Fusion (1957-1962)

International Nuclear Information System (INIS)

Curli, Barbara

2017-01-01

This chapter traces the early origins of European collaboration in controlled thermonuclear fusion research, within the larger picture of Cold War nuclear policy in the late 1950s-early 1960s, and as a consequence of the signing of the EURATOM treaty in 1957. It then presents some preliminary findings on the Association contract which was signed in 1960 between EURATOM and Italy, in order to carry out research in controlled thermonuclear fusion at the then newly created 'Laboratori nazionali di Frascati', near Rome, within the framework of the Comitato Nazionale Energia Nucleare (CNEN), the Italian civilian nuclear energy agency.

Multimodal fusion framework: a multiresolution approach for emotion classification and recognition from physiological signals.

Science.gov (United States)

Verma, Gyanendra K; Tiwary, Uma Shanker

2014-11-15

The purpose of this paper is twofold: (i) to investigate the emotion representation models and find out the possibility of a model with minimum number of continuous dimensions and (ii) to recognize and predict emotion from the measured physiological signals using multiresolution approach. The multimodal physiological signals are: Electroencephalogram (EEG) (32 channels) and peripheral (8 channels: Galvanic skin response (GSR), blood volume pressure, respiration pattern, skin temperature, electromyogram (EMG) and electrooculogram (EOG)) as given in the DEAP database. We have discussed the theories of emotion modeling based on i) basic emotions, ii) cognitive appraisal and physiological response approach and iii) the dimensional approach and proposed a three continuous dimensional representation model for emotions. The clustering experiment on the given valence, arousal and dominance values of various emotions has been done to validate the proposed model. A novel approach for multimodal fusion of information from a large number of channels to classify and predict emotions has also been proposed. Discrete Wavelet Transform, a classical transform for multiresolution analysis of signal has been used in this study. The experiments are performed to classify different emotions from four classifiers. The average accuracies are 81.45%, 74.37%, 57.74% and 75.94% for SVM, MLP, KNN and MMC classifiers respectively. The best accuracy is for 'Depressing' with 85.46% using SVM. The 32 EEG channels are considered as independent modes and features from each channel are considered with equal importance. May be some of the channel data are correlated but they may contain supplementary information. In comparison with the results given by others, the high accuracy of 85% with 13 emotions and 32 subjects from our proposed method clearly proves the potential of our multimodal fusion approach. Copyright © 2013 Elsevier Inc. All rights reserved.

TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice.

Science.gov (United States)

Li, Xiang; Han, Wei-Qing; Boini, Krishna M; Xia, Min; Zhang, Yang; Li, Pin-Lan

2013-01-01

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptor, death receptor 4 (DR4), have been implicated in the development of endothelial dysfunction and atherosclerosis. However, the signaling mechanism mediating DR4 activation leading to endothelial injury remains unclear. We recently demonstrated that ceramide production via hydrolysis of membrane sphingomyelin by acid sphingomyelinase (ASM) results in membrane raft (MR) clustering and the formation of important redox signaling platforms, which play a crucial role in amplifying redox signaling in endothelial cells leading to endothelial dysfunction. The present study aims to investigate whether TRAIL triggers MR clustering via lysosome fusion and ASM activation, thereby conducting transmembrane redox signaling and changing endothelial function. Using confocal microscopy, we found that TRAIL induced MR clustering and co-localized with DR4 in coronary arterial endothelial cells (CAECs) isolated from wild-type (Smpd1 (+/+)) mice. Furthermore, TRAIL triggered ASM translocation, ceramide production, and NADPH oxidase aggregation in MR clusters in Smpd1 ( +/+ ) CAECs, whereas these observations were not found in Smpd1 (-/-) CAECs. Moreover, ASM deficiency reduced TRAIL-induced O(2) (-[Symbol: see text]) production in CAECs and abolished TRAIL-induced impairment on endothelium-dependent vasodilation in small resistance arteries. By measuring fluorescence resonance energy transfer, we found that Lamp-1 (lysosome membrane marker protein) and ganglioside G(M1) (MR marker) were trafficking together in Smpd1 (+/+) CAECs, which was absent in Smpd1 (-/-) CAECs. Consistently, fluorescence imaging of living cells with specific lysosome probes demonstrated that TRAIL-induced lysosome fusion with membrane was also absent in Smpd1 (-/-) CAECs. Taken together, these results suggest that ASM is essential for TRAIL-induced lysosomal trafficking, membrane fusion and formation of MR redox signaling platforms

Improved Controls for Fusion RF Systems. Final technical report

Energy Technology Data Exchange (ETDEWEB)

Casey, Jeffrey A. [Rockfield Research Inc., Las Vegas, NV (United States)

2011-11-08

We have addressed the specific requirements for the integrated systems controlling an array of klystrons used for Lower Hybrid Current Drive (LHCD). The immediate goal for our design was to modernize the transmitter protection system (TPS) for LHCD on the Alcator C-Mod tokamak at the MIT Plasma Science and Fusion Center (MIT-PSFC). Working with the Alcator C-Mod team, we have upgraded the design of these controls to retrofit for improvements in performance and safety, as well as to facilitate the upcoming expansion from 12 to 16 klystrons. The longer range goals to generalize the designs in such a way that they will be of benefit to other programs within the international fusion effort was met by designing a system which was flexible enough to address all the MIT system requirements, and modular enough to adapt to a large variety of other requirements with minimal reconfiguration.

Improved Controls for Fusion RF Systems. Final technical report

International Nuclear Information System (INIS)

Casey, Jeffrey A.

2011-01-01

We have addressed the specific requirements for the integrated systems controlling an array of klystrons used for Lower Hybrid Current Drive (LHCD). The immediate goal for our design was to modernize the transmitter protection system (TPS) for LHCD on the Alcator C-Mod tokamak at the MIT Plasma Science and Fusion Center (MIT-PSFC). Working with the Alcator C-Mod team, we have upgraded the design of these controls to retrofit for improvements in performance and safety, as well as to facilitate the upcoming expansion from 12 to 16 klystrons. The longer range goals to generalize the designs in such a way that they will be of benefit to other programs within the international fusion effort was met by designing a system which was flexible enough to address all the MIT system requirements, and modular enough to adapt to a large variety of other requirements with minimal reconfiguration

Robust QRS peak detection by multimodal information fusion of ECG and blood pressure signals.

Science.gov (United States)

Ding, Quan; Bai, Yong; Erol, Yusuf Bugra; Salas-Boni, Rebeca; Zhang, Xiaorong; Hu, Xiao

2016-11-01

QRS peak detection is a challenging problem when ECG signal is corrupted. However, additional physiological signals may also provide information about the QRS position. In this study, we focus on a unique benchmark provided by PhysioNet/Computing in Cardiology Challenge 2014 and Physiological Measurement focus issue: robust detection of heart beats in multimodal data, which aimed to explore robust methods for QRS detection in multimodal physiological signals. A dataset of 200 training and 210 testing records are used, where the testing records are hidden for evaluating the performance only. An information fusion framework for robust QRS detection is proposed by leveraging existing ECG and ABP analysis tools and combining heart beats derived from different sources. Results show that our approach achieves an overall accuracy of 90.94% and 88.66% on the training and testing datasets, respectively. Furthermore, we observe expected performance at each step of the proposed approach, as an evidence of the effectiveness of our approach. Discussion on the limitations of our approach is also provided.

Controlled thermonuclear fusion: research on magnetic fusion

International Nuclear Information System (INIS)

Paris, P.J.

1988-12-01

Recent progress in thermonuclear fusion research indicates that the scientists' schedule for the demonstration of the scientific feasibility will be kept and that break-even will be attained in the course of the next decade. To see the implementation of ignition, however, the generation of future experiments must be awaited. These projects are currently under study. With technological research going on in parallel, they should at the same time contribute to the design of a reactor. Fusion reactors will be quite different from the fission nuclear reactors we know, and the waste of the plants will also be of a different nature. It is still too early to define the precise design of a fusion reactor. On the basis of a toric machine concept like that of the tokamak, we can, however, envisage that the problems with which we are confronted will be solved one after the other. As we have just seen, these will be the objectives of the future experimental installations where ignition will be possible and where the flux of fast neutrons will be so strong that they will allow the study of low-activation materials which will be used in the structure of the reactor. But this is also a task in which from now onwards numerous laboratories in Europe and in the world participate. The works are in fact punctiform, and often the mutual incidences can only be determined by an approach simulated by numerical codes. (author) 19 figs., 6 tabs., 8 refs

An RFID-Based Intelligent Vehicle Speed Controller Using Active Traffic Signals

Directory of Open Access Journals (Sweden)

Joshué Pérez

2010-06-01

Full Text Available These days, mass-produced vehicles benefit from research on Intelligent Transportation System (ITS. One prime example of ITS is vehicle Cruise Control (CC, which allows it to maintain a pre-defined reference speed, to economize on fuel or energy consumption, to avoid speeding fines, or to focus all of the driver’s attention on the steering of the vehicle. However, achieving efficient Cruise Control is not easy in roads or urban streets where sudden changes of the speed limit can happen, due to the presence of unexpected obstacles or maintenance work, causing, in inattentive drivers, traffic accidents. In this communication we present a new Infrastructure to Vehicles (I2V communication and control system for intelligent speed control, which is based upon Radio Frequency Identification (RFID technology for identification of traffic signals on the road, and high accuracy vehicle speed measurement with a Hall effect-based sensor. A fuzzy logic controller, based on sensor fusion of the information provided by the I2V infrastructure, allows the efficient adaptation of the speed of the vehicle to the circumstances of the road. The performance of the system is checked empirically, with promising results.

An RFID-Based Intelligent Vehicle Speed Controller Using Active Traffic Signals

Science.gov (United States)

Pérez, Joshué; Seco, Fernando; Milanés, Vicente; Jiménez, Antonio; Díaz, Julio C.; de Pedro, Teresa

2010-01-01

These days, mass-produced vehicles benefit from research on Intelligent Transportation System (ITS). One prime example of ITS is vehicle Cruise Control (CC), which allows it to maintain a pre-defined reference speed, to economize on fuel or energy consumption, to avoid speeding fines, or to focus all of the driver’s attention on the steering of the vehicle. However, achieving efficient Cruise Control is not easy in roads or urban streets where sudden changes of the speed limit can happen, due to the presence of unexpected obstacles or maintenance work, causing, in inattentive drivers, traffic accidents. In this communication we present a new Infrastructure to Vehicles (I2V) communication and control system for intelligent speed control, which is based upon Radio Frequency Identification (RFID) technology for identification of traffic signals on the road, and high accuracy vehicle speed measurement with a Hall effect-based sensor. A fuzzy logic controller, based on sensor fusion of the information provided by the I2V infrastructure, allows the efficient adaptation of the speed of the vehicle to the circumstances of the road. The performance of the system is checked empirically, with promising results. PMID:22219692

An RFID-based intelligent vehicle speed controller using active traffic signals.

Science.gov (United States)

Pérez, Joshué; Seco, Fernando; Milanés, Vicente; Jiménez, Antonio; Díaz, Julio C; de Pedro, Teresa

2010-01-01

These days, mass-produced vehicles benefit from research on Intelligent Transportation System (ITS). One prime example of ITS is vehicle Cruise Control (CC), which allows it to maintain a pre-defined reference speed, to economize on fuel or energy consumption, to avoid speeding fines, or to focus all of the driver's attention on the steering of the vehicle. However, achieving efficient Cruise Control is not easy in roads or urban streets where sudden changes of the speed limit can happen, due to the presence of unexpected obstacles or maintenance work, causing, in inattentive drivers, traffic accidents. In this communication we present a new Infrastructure to Vehicles (I2V) communication and control system for intelligent speed control, which is based upon Radio Frequency Identification (RFID) technology for identification of traffic signals on the road, and high accuracy vehicle speed measurement with a Hall effect-based sensor. A fuzzy logic controller, based on sensor fusion of the information provided by the I2V infrastructure, allows the efficient adaptation of the speed of the vehicle to the circumstances of the road. The performance of the system is checked empirically, with promising results.

Twentyseventh European physical society conference on controlled fusion and plasma physics

International Nuclear Information System (INIS)

Igitkhanov, Y.

2000-01-01

The twentyseventh European physical society conference on controlled fusion and plasma physics was held in Budapest, 12-16 June 2000. About 10 invited papers were presented, covering a wide range of problems in plasma physics, including confinement and transport issues in fusion devices, astrophysics and industrial application of plasmas. More than 100 papers were presented on plasma theory and experiments from tokamaks and stellarators. Some of the ITER-relevant issues covered are described in this newsletter

Line-Tension Controlled Mechanism for Influenza Fusion

NARCIS (Netherlands)

Risselada, Herre Jelger; Marelli, Giovanni; Fuhrmans, Marc; Smirnova, Yuliya G.; Grubmueller, Helmut; Marrink, Siewert Jan; Mueller, Marcus

2012-01-01

Our molecular simulations reveal that wild-type influenza fusion peptides are able to stabilize a highly fusogenic pre-fusion structure, i.e. a peptide bundle formed by four or more trans-membrane arranged fusion peptides. We rationalize that the lipid rim around such bundle has a non-vanishing rim

Implications of the second law for future directions in controlled fusion research

International Nuclear Information System (INIS)

Roth, J.R.; Miley, G.H.

1980-01-01

Many existing energy related technologies have developed under the influence of social, economic, or state of the art constraints, and they cannot be viewed as optimum systems according to the second law of thermodynamics. Controlled fusion research presents an opportunity to optimize a nascent technology with respect to second law considerations in order to develop a practical energy source. In its present state of development, fusion research offers several independent approaches that may result in a net power producing fusion reactor. This paper discusses how second law considerations might be used to narrow the range of choices that must be made among various fusion fuel cycles. From a second law point of view, the most desirable fusion reactors are those for which the energy of charged particles can be converted directly into d.c. electrical power, while still allowing the energy that could be recovered by an efficient high-temperature 'blanket' to be transported largely by radiation. Fusion research in all major industrialized countries is developing the deuterium-tritium (D-T) fuel cycle for first-generation fusion power plants. It will be shown that other fuel cycles have significant advantages over the D-T fuel cycle according to second law principles. (author)

Remote sensing image fusion

CERN Document Server

Alparone, Luciano; Baronti, Stefano; Garzelli, Andrea

2015-01-01

A synthesis of more than ten years of experience, Remote Sensing Image Fusion covers methods specifically designed for remote sensing imagery. The authors supply a comprehensive classification system and rigorous mathematical description of advanced and state-of-the-art methods for pansharpening of multispectral images, fusion of hyperspectral and panchromatic images, and fusion of data from heterogeneous sensors such as optical and synthetic aperture radar (SAR) images and integration of thermal and visible/near-infrared images. They also explore new trends of signal/image processing, such as

The effect of controlled shot peening on fusion welded joints

International Nuclear Information System (INIS)

Lah, Nur Azida Che; Ali, Aidy; Ismail, Napsiah; Chai, Lim Poon; Mohamed, Abdul Aziz

2010-01-01

This work examines the effect of controlled shot peening (CSP) treatment on the fatigue strength of an ASTM A516 grade 70 carbon steel welded joint. Metallurgical modifications, hardness, elemental compositions, and internal discontinuities, such as porosity, inclusions, lack of penetration, and undercut found in treated and untreated fusion welded joints, were characterized. The fatigue results of as-welded and peened skimmed joints were compared. It was observed that the effect of the CSP and skimming processes improved the fatigue life of the fusion weld by 50% on MMA-welded, 63% on MIG-welded, and 60% on TIG-welded samples.

Burn Control in Fusion Reactors via Nonlinear Stabilization Techniques

International Nuclear Information System (INIS)

Schuster, Eugenio; Krstic, Miroslav; Tynan, George

2003-01-01

Control of plasma density and temperature magnitudes, as well as their profiles, are among the most fundamental problems in fusion reactors. Existing efforts on model-based control use control techniques for linear models. In this work, a zero-dimensional nonlinear model involving approximate conservation equations for the energy and the densities of the species was used to synthesize a nonlinear feedback controller for stabilizing the burn condition of a fusion reactor. The subignition case, where the modulation of auxiliary power and fueling rate are considered as control forces, and the ignition case, where the controlled injection of impurities is considered as an additional actuator, are treated separately.The model addresses the issue of the lag due to the finite time for the fresh fuel to diffuse into the plasma center. In this way we make our control system independent of the fueling system and the reactor can be fed either by pellet injection or by puffing. This imposed lag is treated using nonlinear backstepping.The nonlinear controller proposed guarantees a much larger region of attraction than the previous linear controllers. In addition, it is capable of rejecting perturbations in initial conditions leading to both thermal excursion and quenching, and its effectiveness does not depend on whether the operating point is an ignition or a subignition point.The controller designed ensures setpoint regulation for the energy and plasma parameter β with robustness against uncertainties in the confinement times for different species. Hence, the controller can increase or decrease β, modify the power, the temperature or the density, and go from a subignition to an ignition point and vice versa

Status report on controlled thermonuclear fusion

International Nuclear Information System (INIS)

1990-06-01

The International Fusion Research Council (IFRC), an advisory body to the International Atomic Energy Agency, reports on the current status of fusion; this report updates its 1978 status report. This report contains a General Overview and Executive Summary, and reports on all current approaches to fusion throughout the world; a series of technical reports is to be published elsewhere. This report is timely in that it not only shows progress which has occurred over the past, but interfaces with possible future devices, in particular the International Thermonuclear Experimental Reactor (ITER), whose conceptual design phase is nearing completion. 5 refs, 6 figs

rhBMP-2 for posterolateral instrumented lumbar fusion: a multicenter prospective randomized controlled trial.

Science.gov (United States)

Hurlbert, R John; Alexander, David; Bailey, Stewart; Mahood, James; Abraham, Ed; McBroom, Robert; Jodoin, Alain; Fisher, Charles

2013-12-01

Multicenter randomized controlled trial. To evaluate the effect of recombinant human bone morphogenetic protein (rhBMP-2) on radiographical fusion rate and clinical outcome for surgical lumbar arthrodesis compared with iliac crest autograft. In many types of spinal surgery, radiographical fusion is a primary outcome equally important to clinical improvement, ensuring long-term stability and axial support. Biologic induction of bone growth has become a commonly used adjunct in obtaining this objective. We undertook this study to objectify the efficacy of rhBMP-2 compared with traditional iliac crest autograft in instrumented posterolateral lumbar fusion. Patients undergoing 1- or 2-level instrumented posterolateral lumbar fusion were randomized to receive either autograft or rhBMP-2 for their fusion construct. Clinical and radiographical outcome measures were followed for 2 to 4 years postoperatively. One hundred ninety seven patients were successfully randomized among the 8 participating institutions. Adverse events attributable to the study drug were not significantly different compared with controls. However, the control group experienced significantly more graft-site complications as might be expected. 36-Item Short Form Health Survey, Oswestry Disability Index, and leg/back pain scores were comparable between the 2 groups. After 4 years of follow-up, radiographical fusion rates remained significantly higher in patients treated with rhBMP-2 (94%) than those who received autograft (69%) (P = 0.007). The use of rhBMP-2 for instrumented posterolateral lumbar surgery significantly improves the chances of radiographical fusion compared with the use of autograft. However, there is no associated improvement in clinical outcome within a 4-year follow-up period. These results suggest that use of rhBMP-2 should be considered in cases where lumbar arthrodesis is of primary concern.

Energy balance of controlled thermonuclear fusion

International Nuclear Information System (INIS)

Hashmi, M.; Staudenmaier, G.

2000-01-01

It is shown that a discrepancy and incompatibility persist between basic physics and fusion-literature regarding the radiation losses from a thermonuclear plasma. Whereas the fusion-literature neglects the excitation or line radiation completely, according to basic physics it depends upon the prevailing conditions and cannot be neglected in general. Moreover, for a magnetized plasma, while the fusion-literature assumes a self-absorption or reabsorption of cyclotron or synchrotron radiation emitted by the electrons spiraling along the magnetic field, the basic physics does not allow any effective reabsorption of cyclotron or synchrotron radiation. As is demonstrated, fallacious assumptions and notions, which somehow or other crept into the fusion-literature, are responsible for this discrepancy. In the present work, the theory is corrected. On the grounds of basic physics, a complete energy balance of magnetized and non-magnetized plasmas is presented for pulsed, stationary and self-sustaining operations by taking into account the energy release by reactions of light nuclei as well as different kinds of diffusive (conduction) and radiative (bremsstrahlung, cyclotron or synchrotron radiation and excitation radiation) energy losses. Already the energy losses by radiation make the energy balance negative. Hence, a fusion reactor-an energy producing device-seems to be beyond the realms of realization. (orig.)

Plasma physics for controlled fusion

CERN Document Server

Miyamoto, Kenro

2016-01-01

This new edition presents the essential theoretical and analytical methods needed to understand the recent fusion research of tokamak and alternate approaches. The author describes magnetohydrodynamic and kinetic theories of cold and hot plasmas in detail. The book covers new important topics for fusion studies such as plasma transport by drift turbulence, which depend on the magnetic configuration and zonal flows. These are universal phenomena of microturbulence. They can modify the onset criterion for turbulent transport, instabilities driven by energetic particles as well as alpha particle generation and typical plasma models for computer simulation. The fusion research of tokamaks with various new versions of H modes are explained. The design concept of ITER, the international tokamak experimental reactor, is described for inductively driven operations as well as steady-state operations using non-inductive drives. Alternative approaches of reversed-field pinch and its relaxation process, stellator includi...

Weaving Hilbert space fusion frames

OpenAIRE

Neyshaburi, Fahimeh Arabyani; Arefijamaal, Ali Akbar

2018-01-01

A new notion in frame theory, so called weaving frames has been recently introduced to deal with some problems in signal processing and wireless sensor networks. Also, fusion frames are an important extension of frames, used in many areas especially for wireless sensor networks. In this paper, we survey the notion of weaving Hilbert space fusion frames. This concept can be had potential applications in wireless sensor networks which require distributed processing using different fusion frames...

Operating large controlled thermonuclear fusion research facilities

International Nuclear Information System (INIS)

Gaudreau, M.P.J.; Tarrh, J.M.; Post, R.S.; Thomas, P.

1987-01-01

The MIT Tara Tandem Mirror is a large, state of the art controlled thermonuclear fusion research facility. Over the six years of its design, implementation, and operation, every effort was made to minimize cost and maximize performance by using the best and latest hardware, software, and scientific and operational techniques. After reviewing all major DOE fusion facilities, an independent DOE review committee concluded that the Tara operation was the most automated and efficient of all DOE facilities. This paper includes a review of the key elements of the Tara design, construction, operation, management, physics milestones, and funding that led to this success. The authors emphasize a chronological description of how the system evolved from the proposal stage to a mature device with an emphasis on the basic philosophies behind the implementation process. This description can serve both as a qualitative and quantitative database for future large experiment planning. It includes actual final costs and manpower spent as well as actual run and maintenance schedules, number of data shots, major system failures, etc. The paper concludes with recommendations for the next generation of facilities

Base isolation technique for tokamak type fusion reactor using adaptive control

International Nuclear Information System (INIS)

Koizumi, T.; Tsujiuchi, N.; Kishimoto, F.; Iida, H.; Fujita, T.

1991-01-01

In this paper relating to the isolation device of heavy structure such as nuclear fusion reactor, a control rule for reducing the response acceleration and relative displacement simultaneously was formulated, and the aseismic performance was improved by employing the adaptive control method of changing the damping factors of the system adaptively every moment. The control rule was studied by computer simulation, and the aseismic effect was evaluated in an experiment employing a scale model. As a results, the following conclusions were obtained. (1) By employing the control rule presented in this paper, both absolute acceleration and relative displacement can be reduced simultaneously without making the system unstable. (2) By introducing this control rule in a scale model assuming the Tokamak type fusion reactor, the response acceleration can be suppressed down to 78 % and also the relative displacement to 79 % as compared with the conventional aseismic method. (3) The sensitivities of absolute acceleration and relative displacement with respect to the control gain are not equal. However, by employing the relative weighting factor between the absolute acceleration and relative displacement, it is possible to increase the control capability for any kind of objective structures and appliances. (author)

Controlled thermonuclear fusion

International Nuclear Information System (INIS)

Rebut, P.H.

1992-01-01

The author gives a chronological account of the research about thermonuclear fusion and presents the principle of JET thermonuclear reactor based upon the magnetic confinement. The problems of heating and confining a thermonuclear plasma may be regarded as solved. They make possible the definition of the size and geometry needed to realize a next-step tokamak (ITER, NET projects)

Risk assessment of computer-controlled safety systems for fusion reactors

International Nuclear Information System (INIS)

Fryer, M.O.; Bruske, S.Z.

1983-01-01

The complexity of fusion reactor systems and the need to display, analyze, and react promptly to large amounts of information during reactor operation will require a number of safety systems in the fusion facilities to be computer controlled. Computer software, therefore, must be included in the reactor safety analyses. Unfortunately, the science of integrating computer software into safety analyses is in its infancy. Combined plant hardware and computer software systems are often treated by making simple assumptions about software performance. This method is not acceptable for assessing risks in the complex fusion systems, and a new technique for risk assessment of combined plant hardware and computer software systems has been developed. This technique is an extension of the traditional fault tree analysis and uses structured flow charts of the software in a manner analogous to wiring or piping diagrams of hardware. The software logic determines the form of much of the fault trees

Circumferential fusion is dominant over posterolateral fusion in a long-term perspective: cost-utility evaluation of a randomized controlled trial in severe, chronic low back pain

DEFF Research Database (Denmark)

Soegaard, Rikke; Bünger, Cody E; Christiansen, Terkel

2007-01-01

STUDY DESIGN: Cost-utility evaluation of a randomized, controlled trial with a 4- to 8-year follow-up. OBJECTIVE: To investigate the incremental cost per quality-adjusted-life-year (QALY) when comparing circumferential fusion to posterolateral fusion in a long-term, societal perspective. SUMMARY...... OF BACKGROUND DATA: The cost-effectiveness of circumferential fusion in a long-term perspective is uncertain but nonetheless highly relevant as the ISSLS prize winner 2006 in clinical studies reported the effect of circumferential fusion superior to the effect of posterolateral fusion. A recent trial found...... no significant difference between posterolateral and circumferential fusion reporting cost-effectiveness from a 2-year viewpoint. METHODS: A total of 146 patients were randomized to posterolateral or circumferential fusion and followed 4 to 8 years after surgery. The mean age of the cohort was 46 years (range...

The fusion-fission hybrid

International Nuclear Information System (INIS)

Teller, E.

1985-01-01

As the history of the development of fusion energy shows, a sustained controlled fusion reaction is much more difficult to produce than rapid uncontrolled release of fusion energy. Currently, the ''magnetic bottle'' technique shows sufficient progress that it might applied for the commercial fuel production of /sup 233/U, suitable for use in fission reactors, by developing a fusion-fission hybrid. Such a device would consist of a fusion chamber core surrounded by a region containing cladded uranium pellets cooled by helium, with lithium salts also present to produce tritium to refuel the fusion process. Successful development of this hybrid might be possible within 10 y, and would provide both experience and funds for further development of controlled fusion energy

Plasma Surface interaction in Controlled fusion devices

International Nuclear Information System (INIS)

1990-05-01

The subjects presented in the 9th conference on plasma surface interaction in controlled fusion devices were: the modifications of power scrape-off-length and power deposition during various configurations in Tore Supra plasmas; the effects observed in ergodic divertor experiments in Tore-Supra; the diffuse connexion induced by the ergodic divertor and the topology of the heat load patterns on the plasma facing components in Tore-Supra; the study of the influence of air exposure on graphite implanted by low energy high density deuterium plasma

Toroidal electron beam energy storage for controlled fusion

International Nuclear Information System (INIS)

Clark, W.; Korn, P.; Mondelli, A.; Rostoker, N.

1976-01-01

In the presence of an external magnetic field stable equilibria exist for an unneutralized electron beam with ν/γ >1. As a result, it is in principle, possible to store very large quantities of energy in relatively small volumes by confining an unneutralized electron beam in a Tokamak-like device. The energy is stored principally in the electrostatic and self-magnetic fields associated with the beam and is available for rapid heating of pellets for controlled fusion. The large electrostatic potential well in such a device would be sufficient to contain energetic alpha particles, thereby reducing reactor wall bombardment. This approach also avoids plasma loss and wall bombardment by charge exchange neutrals. The conceptual design of an electrostatic Tokamak fusion reactor (ETFR) is discussed. A small toroidal device (the STP machine) has been constructed to test the principles involved. Preliminary experiments on this device have produced electron densities approximately 10% of those required in a reactor

Research program. Controlled thermonuclear fusion. Synthesis report 2014

International Nuclear Information System (INIS)

Villard, L.; Marot, L.; Fiocco, D.

2015-01-01

In 1961, 3 years after the 2 nd International Conference on Peaceful Use of Nuclear Energy, the Research Centre on Plasma Physics (CRPP) was created as a department of the Federal Institute of Technology (EPFL) in Lausanne (Switzerland). From 1979, CRPP collaborates to the European Program on fusion research in the framework of EURATOM. The advantages of fusion are remarkable: the fuel is available in great quantity all over the world; the reactor is intrinsically safe; the reactor material, activated during operation, loses practically all its activity within about 100 years. But the working up of the controlled fusion necessitates extreme technological conditions. In 1979, the Joint European Torus (JET) began its operation; today it is still the most powerful tokamak in the world; its energy yield Q reached 0.65. The progress realized in the framework of EURATOM has led to the planning of the experimental reactor ITER which is being built at Cadarache (France). ITER is designed to reach a Q-value largely above 1. The future prototype reactor DEMO is foreseen in 2040-2050. It should demonstrate the ability of a fusion reactor to inject electricity into the grid for long term. In 2014, CRPP participated in the works on ITER in the framework of the Fusion for Energy (F4E) agency. At EPFL the research concerns the physics of the magnetic confinement with experiments on the tokamak TCV (variable configuration tokamak), the numerical simulations, the plasma heating and the generation of current by hyper frequency radio waves. At the Paul Scherrer Institute (PSI), research is devoted to the superconductivity. At the Basel University the studies get on interactions between the plasma and the tokamak walls. The large flexibility of TCV allows creating and controlling plasmas of different shapes which are necessary to optimise the core geometry of future reactors. Moreover, the plasma heating by mm radio waves allows guiding the injected power according to specific

Control of plasma layer in a fusion reactor correlated to DC motor control using PSO-ANFIS

International Nuclear Information System (INIS)

Mahapatra, Sakuntala; Daniel, Raju; Dey, Deep Narayan

2013-01-01

Plasma position and shape control is very crucial for the overall performance of the fusion reactor such as Tokamak. The quality of the discharge in the Saskatchewan TORus-Modified (STOR-M) tokamak is strongly related to the position of the plasma column within the discharge vessel. If the plasma column approaches too near the wall, then either minor or complete disruption occurs. Consequently it is necessary to be able to control dynamically the position of the plasma column throughout the entire discharge. Now a day's most fusion reactor employs the traditional PID controller for the confinement of plasma layer. Fuzzy logic is used for the control of Plasma layer. In this paper we have used the hybrid of PSO-ANFIS technique to control the speed of a DC motor. We have used two input parameters like speed, torque and output is firing angle. In our work first order Sugeno fuzzy model is taken with three rules and the parameters of Gaussian membership function is controlled by the PSO technique. PSO-ANFIS speed controller obtains better dynamic behavior and superior performance of the DC motor speed control. Similar approach can be correlated to the control of plasma layer. For the plasma control two inputs can be taken as plasma position ΔH and the plasma current and the single output, the control decision u(t). (author)

Organotypic three-dimensional culture model of mesenchymal and epithelial cells to examine tissue fusion events.

Science.gov (United States)

Tissue fusion during early mammalian development requires coordination of multiple cell types, the extracellular matrix, and complex signaling pathways. Fusion events during processes including heart development, neural tube closure, and palatal fusion are dependent on signaling ...

Control and data acquisition ATCA/AXIe board designed for high system availability and reliability of nuclear fusion experiments

International Nuclear Information System (INIS)

Batista, A.J.N.; Leong, C.; Bexiga, V.; Rodrigues, A.P.; Combo, A.; Carvalho, B.B.; Carvalho, P.F.; Fortunato, J.; Santos, B.; Carvalho, P.; Correia, M.; Teixeira, J.P.; Teixeira, I.C.; Sousa, J.; Gonçalves, B.; Varandas, C.A.F.

2013-01-01

This paper describes the implementation and test of a control and data acquisition board designed to be integrated on systems demanding high availability and reliability, foreseen for future experiments like ITER or other long operation fusion devices. The Advanced Telecommunications Computing Architecture (ATCA) standard (PICMG 3.0 and 3.4) was selected for board implementation, which has support for the desired system robustness and performance. Some board features such as rear Input/Output (IO) signals connectivity (passive, copper tracks only), cable-less hot-swap maintenance, Intelligent Platform Management Controller (IPMC) and redundancy on timing signals, communications links and power supplies are significant board improvements, relatively to previous control and data acquisition boards, allowing the development of more reliable system architectures. Moreover, the developed board is also compatible with the emerging ATCA eXtensions for Instrumentation (AXIe) specifications, which provides additional timing and synchronization signals on the backplane. ATCA full-mesh, multi-gigabit, full-duplex, point-to-point communication links between Field Programmable Gate Arrays (FPGA), of peer boards inside the shelf, allow the implementation of distributed algorithms and development of Multi-Input Multi-Output (MIMO) systems. Up to 48 analog input channels, simultaneously digitized (2 MSPS @ 18-bits), are filtered/decimated by the board FPGA and sent to the ATCA/AXIe host through Peripheral Component Interconnect express (PCIe) using Direct Memory Access (DMA). In real-time, the host can update up to 48 analog output channels (1 MSPS @ 18-bits), per board, through PCIe. Further board characteristics comprise analog IO channels with galvanic isolation and an optional signal chopper mode, for offset compensation over time on digital integration of magnetic signals. Board time synchronization is attained by means of the Inter-Range Instrumentation Group (IRIG) time-code

Operating large controlled thermonuclear fusion research facilities

International Nuclear Information System (INIS)

Gaudreau, M.P.J.; Tarrh, J.M.; Post, R.S.; Thomas, P.

1987-10-01

The MIT Tara Tandem Mirror is a large, state of the art controlled thermonuclear fusion research facility. Over the six years of its design, implementation, and operation, every effort was made to minimize cost and maximize performance by using the best and latest hardware, software, and scientific and operational techniques. After reviewing all major DOE fusion facilities, an independent DOE review committee concluded that the Tara operation was the most automated and efficient of all DOE facilities. This paper includes a review of the key elements of the Tara design, construction, operation, management, physics milestones, and funding that led to this success. We emphasize a chronological description of how the system evolved from the proposal stage to a mature device with an emphasis on the basic philosophies behind the implementation process. This description can serve both as a qualitative and quantitative database for future large experiment planning. It includes actual final costs and manpower spent as well as actual run and maintenance schedules, number of data shots, major system failures, etc. The paper concludes with recommendations for the next generation of facilities. 13 refs., 15 figs., 3 tabs

Computational and biological characterization of fusion proteins of two insecticidal proteins for control of insect pests.

Science.gov (United States)

Javaid, Shaista; Naz, Sehrish; Amin, Imran; Jander, Georg; Ul-Haq, Zaheer; Mansoor, Shahid

2018-03-19

Sucking pests pose a serious agricultural challenge, as available transgenic technologies such as Bacillus thuringiensis crystal toxins (Bt) are not effective against them. One approach is to produce fusion protein toxins for the control of these pests. Two protein toxins, Hvt (ω-atracotoxin from Hadronyche versuta) and onion leaf lectin, were translationally fused to evaluate the negative effects of fusion proteins on Phenacoccus solenopsis (mealybug), a phloem-feeding insect pest. Hvt was cloned both N-terminally (HL) and then C-terminally (LH) in the fusion protein constructs, which were expressed transiently in Nicotiana tabacum using a Potato Virus X (PVX) vector. The HL fusion protein was found to be more effective against P. solenopsis, with an 83% mortality rate, as compared to the LH protein, which caused 65% mortality. Hvt and lectin alone caused 42% and 45%, respectively, under the same conditions. Computational studies of both fusion proteins showed that the HL protein is more stable than the LH protein. Together, these results demonstrate that translational fusion of two insecticidal proteins improved the insecticidal activity relative to each protein individually and could be expressed in transgenic plants for effective control of sucking pests.

Cell fusions in mammals

DEFF Research Database (Denmark)

Larsson, Lars-Inge; Bjerregaard, Bolette; Talts, Jan Fredrik

2008-01-01

Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression. A large number of factors appear...... to regulate cell fusions, including receptors and ligands, membrane domain organizing proteins, proteases, signaling molecules and fusogenic proteins forming alpha-helical bundles that bring membranes close together. The syncytin family of proteins represent true fusogens and the founding member, syncytin-1......, has been documented to be involved in fusions between placental trophoblasts, between cancer cells and between cancer cells and host ells. We review the literature with emphasis on the syncytin family and propose that syncytins may represent universal fusogens in primates and rodents, which work...

Modular control of fusion power heating applications

International Nuclear Information System (INIS)

Demers, D. R.

2012-01-01

This work is motivated by the growing demand for auxiliary heating on small and large machines worldwide. Numerous present and planned RF experiments (EBW, Lower Hybrid, ICRF, and ECH) are increasingly complex systems. The operational challenges are indicative of a need for components of real-time control that can be implemented with a moderate amount of effort in a time- and cost-effective fashion. Such a system will improve experimental efficiency, enhance experimental quality, and expedite technological advancements. The modular architecture of this control-suite serves multiple purposes. It facilitates construction on various scales from single to multiple controller systems. It enables expandability of control from basic to complex via the addition of modules with varying functionalities. It simplifies the control implementation process by reducing layers of software and electronic development. While conceived with fusion applications in mind, this suite has the potential to serve a broad range of scientific and industrial applications. During the Phase-I research effort we established the overall feasibility of this modular control-suite concept. We developed the fundamental modules needed to implement open-loop active-control and demonstrated their use on a microwave power deposition experiment

MR tomography in the assessment of functional stability of posterolateral lumbar fusions

International Nuclear Information System (INIS)

Lang, P.; Genant, H.K.; Chafetz, N.; Steiger, P.; Stoller, D.; California Univ., San Francisco

1987-01-01

MR tomography was used to assess functional lumbar stability in 30 patients with posterolateral fusions. The vertebral bodies of 9 of the 12 patients with unstable lumbar fusions presented with areas of decreased signal intensity on T 1 - and intermediately weighted images, which increased on T 2 -weighting. The vertebrae of 15 of the 18 patients with stable fusions demonstrated zones of increased signal intensity on T 1 - and intermediately weighted images, which were less intense or invisible on T 2 -weighting. Surgical correlation was available in 11 of the 30 patients studied. Hyperemia and inflammation appear to be responsible for the abnormal signal intensities in the patients with stable fusions, whereas an increase in adipose marrow due to decreased biomechanical stress is thought to account for the atypical signal intensities in the vertebral bodies of the patients with stable fusions. MR tomography seems to be a potential method for evaluating functional lumbar fusion stability. MR tomography may be particularly helpful in those patients with multiple back surgeries and possible instability, recurrent disc herniation, or post-operative fibrosis. MR is recommended in the patient, who appears clinically unstable, whose radiographs and CT, however, do not demonstrate fusion failure. (orig.) [de

Local control station for development, testing and maintenance of mirror fusion facility subsystem controls

International Nuclear Information System (INIS)

Ables, E.; Kelly, M.F.

1985-01-01

A Local Control Station (LCS) was designed and built to provide a simplified ad easily configurable means of controlling any Mirror Fusion Test Facility (MFTF-B) subsystem for the purpose of development, testing and maintenance of the subsystem. All MFTF-B Subsystems incorporate at least one Local Control Computer (LCC) that is connected to and accepts high level commands from one of the Supervisory Control and Diagnostic System (SCDS) computers. The LCS connects directly to the LCC in place of SCDS. The LCS communicates with the subsystem hardware using the same SCDS commands that the local control computer recognizes and as such requires no special configuration of the LCC

Integrative Multi-Spectral Sensor Device for Far-Infrared and Visible Light Fusion

Science.gov (United States)

Qiao, Tiezhu; Chen, Lulu; Pang, Yusong; Yan, Gaowei

2018-06-01

Infrared and visible light image fusion technology is a hot spot in the research of multi-sensor fusion technology in recent years. Existing infrared and visible light fusion technologies need to register before fusion because of using two cameras. However, the application effect of the registration technology has yet to be improved. Hence, a novel integrative multi-spectral sensor device is proposed for infrared and visible light fusion, and by using the beam splitter prism, the coaxial light incident from the same lens is projected to the infrared charge coupled device (CCD) and visible light CCD, respectively. In this paper, the imaging mechanism of the proposed sensor device is studied with the process of the signals acquisition and fusion. The simulation experiment, which involves the entire process of the optic system, signal acquisition, and signal fusion, is constructed based on imaging effect model. Additionally, the quality evaluation index is adopted to analyze the simulation result. The experimental results demonstrate that the proposed sensor device is effective and feasible.

Sensor fusion IV: Control paradigms and data structures; Proceedings of the Meeting, Boston, MA, Nov. 12-15, 1991

Science.gov (United States)

Schenker, Paul S. (Editor)

1992-01-01

Various papers on control paradigms and data structures in sensor fusion are presented. The general topics addressed include: decision models and computational methods, sensor modeling and data representation, active sensing strategies, geometric planning and visualization, task-driven sensing, motion analysis, models motivated biology and psychology, decentralized detection and distributed decision, data fusion architectures, robust estimation of shapes and features, application and implementation. Some of the individual subjects considered are: the Firefly experiment on neural networks for distributed sensor data fusion, manifold traversing as a model for learning control of autonomous robots, choice of coordinate systems for multiple sensor fusion, continuous motion using task-directed stereo vision, interactive and cooperative sensing and control for advanced teleoperation, knowledge-based imaging for terrain analysis, physical and digital simulations for IVA robotics.

Resource-Efficient Fusion with Pre-Compensated Transmissions for Cooperative Spectrum Sensing

Directory of Open Access Journals (Sweden)

Dayan Adionel Guimarães

2015-05-01

Full Text Available Recently, a novel fusion scheme for cooperative spectrum sensing was proposed for saving resources in the control channel. Secondary users (SUs simultaneously report their decisions using binary modulations with the same carrier frequencies. The transmitted symbols add incoherently at the fusion centre (FC, leading to a larger set of symbols in which a subset is associated with the presence of the primary user (PU signal, and another subset is associated with the absence of such a signal. The decision criterion applied for discriminating these subsets works under the assumption that the channel gains are known at the FC. In this paper, we propose a new simultaneous transmission and decision scheme in which the task of channel estimation is shifted from the FC to the SUs, without the need for feeding-back of the estimates to the FC. The estimates are used at the SUs to pre-compensate for the reporting channel phase rotations and to partially compensate for the channel gains. This partial compensation is the result of signal clipping for peak-to-average power ratio (PAPR control. We show, analytically and with simulations, that this new scheme can produce large performance improvements, yet reduces the implementation complexity when compared with the original one.

Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/PTPN12.

Science.gov (United States)

Rhee, Inmoo; Davidson, Dominique; Souza, Cleiton Martins; Vacher, Jean; Veillette, André

2013-06-01

Macrophages can undergo cell-cell fusion, leading to the formation of multinucleated giant cells and osteoclasts. This process is believed to promote the proteolytic activity of macrophages toward pathogens, foreign bodies, and extracellular matrices. Here, we examined the role of PTP-PEST (PTPN12), a cytoplasmic protein tyrosine phosphatase, in macrophage fusion. Using a macrophage-targeted PTP-PEST-deficient mouse, we determined that PTP-PEST was not needed for macrophage differentiation or cytokine production. However, it was necessary for interleukin-4-induced macrophage fusion into multinucleated giant cells in vitro. It was also needed for macrophage fusion following implantation of a foreign body in vivo. Moreover, in the RAW264.7 macrophage cell line, PTP-PEST was required for receptor activator of nuclear factor kappa-B ligand (RANKL)-triggered macrophage fusion into osteoclasts. PTP-PEST had no impact on expression of fusion mediators such as β-integrins, E-cadherin, and CD47, which enable macrophages to become fusion competent. However, it was needed for polarization of macrophages, migration induced by the chemokine CC chemokine ligand 2 (CCL2), and integrin-induced spreading, three key events in the fusion process. PTP-PEST deficiency resulted in specific hyperphosphorylation of the protein tyrosine kinase Pyk2 and the adaptor paxillin. Moreover, a fusion defect was induced upon treatment of normal macrophages with a Pyk2 inhibitor. Together, these data argue that macrophage fusion is critically dependent on PTP-PEST. This function is seemingly due to the ability of PTP-PEST to control phosphorylation of Pyk2 and paxillin, thereby regulating cell polarization, migration, and spreading.

Controllers for high-performance nuclear fusion plasmas

NARCIS (Netherlands)

Baar, de M.R.

2012-01-01

A succesful nuclear fusion reactor will confine plasma at hig temperatures and densities, with low thermal losses. The workhorse of the nuclear fusion community is the tokamak, a toroidal device in which plasmas are confined by poloidal and toroidal magnetic fields. Ideally, the confirming magnetic

Multi-agent control system with information fusion based comfort model for smart buildings

International Nuclear Information System (INIS)

Wang, Zhu; Wang, Lingfeng; Dounis, Anastasios I.; Yang, Rui

2012-01-01

Highlights: ► Proposed a model to manage indoor energy and comfort for smart buildings. ► Developed a control system to maximize comfort with minimum energy consumption. ► Information fusion with ordered weighted averaging aggregation is used. ► Multi-agent technology and heuristic intelligent optimization are deployed in developing the control system. -- Abstract: From the perspective of system control, a smart and green building is a large-scale dynamic system with high complexity and a huge amount of information. Proper combination of the available information and effective control of the overall building system turns out to be a big challenge. In this study, we proposed a building indoor energy and comfort management model based on information fusion using ordered weighted averaging (OWA) aggregation. A multi-agent control system with heuristic intelligent optimization is developed to achieve a high level of comfort with the minimum power consumption. Case studies and simulation results are presented and discussed in this paper.

Feasibility study of direct spectra measurements for Thomson scattered signals for KSTAR fusion-grade plasmas

Science.gov (United States)

Park, K.-R.; Kim, K.-h.; Kwak, S.; Svensson, J.; Lee, J.; Ghim, Y.-c.

2017-11-01

Feasibility study of direct spectra measurements of Thomson scattered photons for fusion-grade plasmas is performed based on a forward model of the KSTAR Thomson scattering system. Expected spectra in the forward model are calculated based on Selden function including the relativistic polarization correction. Noise in the signal is modeled with photon noise and Gaussian electrical noise. Electron temperature and density are inferred using Bayesian probability theory. Based on bias error, full width at half maximum and entropy of posterior distributions, spectral measurements are found to be feasible. Comparisons between spectrometer-based and polychromator-based Thomson scattering systems are performed with varying quantum efficiency and electrical noise levels.

Fusion--fission hybrid concepts for laser-induced fusion

International Nuclear Information System (INIS)

Maniscalco, J.

1976-01-01

Fusion-fission hybrid concepts are viewed as subcritical fission reactors driven and controlled by high-energy neutrons from a laser-induced fusion reactor. Blanket designs encompassing a substantial portion of the spectrum of different fission reactor technologies are analyzed and compared by calculating their fissile-breeding and fusion-energy-multiplying characteristics. With a large number of different fission technologies to choose from, it is essential to identify more promising hybrid concepts that can then be subjected to in-depth studies that treat the engineering safety, and economic requirements as well as the neutronic aspects. In the course of neutronically analyzing and comparing several fission blanket concepts, this work has demonstrated that fusion-fission hybrids can be designed to meet a broad spectrum of fissile-breeding and fusion-energy-multiplying requirements. The neutronic results should prove to be extremely useful in formulating the technical scope of future studies concerned with evaluating the technical and economic feasibility of hybrid concepts for laser-induced fusion

A Multiple Data Fusion Approach to Wheel Slip Control for Decentralized Electric Vehicles

Directory of Open Access Journals (Sweden)

Dejun Yin

2017-04-01

Full Text Available Currently, active safety control methods for cars, i.e., the antilock braking system (ABS, the traction control system (TCS, and electronic stability control (ESC, govern the wheel slip control based on the wheel slip ratio, which relies on the information from non-driven wheels. However, these methods are not applicable in the cases without non-driven wheels, e.g., a four-wheel decentralized electric vehicle. Therefore, this paper proposes a new wheel slip control approach based on a novel data fusion method to ensure good traction performance in any driving condition. Firstly, with the proposed data fusion algorithm, the acceleration estimator makes use of the data measured by the sensor installed near the vehicle center of mass (CM to calculate the reference acceleration of each wheel center. Then, the wheel slip is constrained by controlling the acceleration deviation between the actual wheel and the reference wheel center. By comparison with non-control and model following control (MFC cases in double lane change tests, the simulation results demonstrate that the proposed control method has significant anti-slip effectiveness and stabilizing control performance.

Interated Intelligent Industrial Process Sensing and Control: Applied to and Demonstrated on Cupola Furnaces

Energy Technology Data Exchange (ETDEWEB)

Mohamed Abdelrahman; roger Haggard; Wagdy Mahmoud; Kevin Moore; Denis Clark; Eric Larsen; Paul King

2003-02-12

The final goal of this project was the development of a system that is capable of controlling an industrial process effectively through the integration of information obtained through intelligent sensor fusion and intelligent control technologies. The industry of interest in this project was the metal casting industry as represented by cupola iron-melting furnaces. However, the developed technology is of generic type and hence applicable to several other industries. The system was divided into the following four major interacting components: 1. An object oriented generic architecture to integrate the developed software and hardware components @. Generic algorithms for intelligent signal analysis and sensor and model fusion 3. Development of supervisory structure for integration of intelligent sensor fusion data into the controller 4. Hardware implementation of intelligent signal analysis and fusion algorithms

Some introductory notes on the problem of nuclear energy by controlled fusion reactions

International Nuclear Information System (INIS)

Pedretti, E.

1988-01-01

Written for scientists and technologist interested in, but unfamiliar with nuclear energy by controlled fusion reactions, this ''sui generis'' review paper attempts to provide the reader, as shortly as possible, with a general idea of the main issues at stake in nuclear fusion research. With the purpose of keeping this paper within a reasonable length, the various subjects are only outlined in their essence, basic features, underlying principles, etc., without entering into details, which are left to the quoted literature. Due to the particular readership of this journal, vacuum problems and/or aspects of fusion research anyhow related with vacuum science and technology are evidentiated. After reviewing fusion reactions' cross sections, fusion by accelerators and muon catalyzed fusion are described, followed by mention of Lawson's criteria and of plasma confinement features. Then, inertial confinement fusion is dealt with, also including one example of laser system (Nova), one of accelerator facility (PBFA-II) and some guesses on the classified Centurion-Halite program. Magnetic confinement fusion research is also reviewed, in particulary reporting one example of linear machine (MFTF-B), two examples of toroidal machines other than Tokamak (ATF and Eta-Beta-II) and various examples of Tokamaks, including PBX and PBX-M; TFTR, JET, JT-60, T-15 and Tore-Supra (large machines); Alcator A, FT, Alcator C/MTX, Alcator C-Mod and T-14 (compact high field machines). Tokamaks under design for ignition experiments (Ignitor, CIT, Ignitex and NET) are also illustrated. Thermal conversion of fusion power and direct generation of electricity are mentioned; conceptual design of fusion power plants are considered and illustrated by four examples (STARFIRE, WILDCAT, MARS and CASCADE). The D 3 He fuel cycle is discussed as an alternative more acceptable than Deuterium-Tritium, and thw Candor proposal is reported. After recalling past experience of the fission power development, some

Diabetes: Models, Signals and control

Science.gov (United States)

Cobelli, C.

2010-07-01

Diabetes and its complications impose significant economic consequences on individuals, families, health systems, and countries. The control of diabetes is an interdisciplinary endeavor, which includes significant components of modeling, signal processing and control. Models: first, I will discuss the minimal (coarse) models which describe the key components of the system functionality and are capable of measuring crucial processes of glucose metabolism and insulin control in health and diabetes; then, the maximal (fine-grain) models which include comprehensively all available knowledge about system functionality and are capable to simulate the glucose-insulin system in diabetes, thus making it possible to create simulation scenarios whereby cost effective experiments can be conducted in silico to assess the efficacy of various treatment strategies - in particular I will focus on the first in silico simulation model accepted by FDA as a substitute to animal trials in the quest for optimal diabetes control. Signals: I will review metabolic monitoring, with a particular emphasis on the new continuous glucose sensors, on the crucial role of models to enhance the interpretation of their time-series signals, and on the opportunities that they present for automation of diabetes control. Control: I will review control strategies that have been successfully employed in vivo or in silico, presenting a promise for the development of a future artificial pancreas and, in particular, I will discuss a modular architecture for building closed-loop control systems, including insulin delivery and patient safety supervision layers.

Design of power control system using SMES and SVC for fusion power plant

International Nuclear Information System (INIS)

Niiyama, K; Yagai, T; Tsuda, M; Hamajima, T

2008-01-01

A SMES (Superconducting Magnetic Energy Storage System) system with converter composed of self-commutated valve devices such as GTO and IGBT is available to control active and reactive power simultaneously. A SVC (Static Var Compensators) or STATCOM (Static Synchronous Compensator) is widely employed to reduce reactive power in power plants and substations. Owing to progress of power electronics technology using GTO and IGBT devices, power converters in the SMES system and the SVC can easily control power flow in few milliseconds. Moreover, since the valve devices for the SMES are equivalent to those for the SVC, the device cost must be reduced. In this paper the basic control system combined with the SMES and SVC is designed for large pulsed loads of a nuclear fusion power plant. This combined system largely expands the reactive power control region as well as the active one. The simulation results show that the combined system is effective and prospective for the nuclear fusion power plant

Dividing traffic cluster into parts by signal control

Science.gov (United States)

Nagatani, Takashi

2018-02-01

When a cluster of vehicles with various speeds moves through the series of signals, the cluster breaks down by stopping at signals and results in smaller groups of vehicles. We present the nonlinear-map model of the motion of vehicles controlled by the signals. We study the breakup of a cluster of vehicles through the series of signals. The cluster of vehicles is divided into various groups by controlling the cycle time of signals. The vehicles within each group move with the same mean velocity. The breakup of the traffic cluster depends highly on the signal control. The dependence of dividing on both cycle time and vehicular speed is clarified. Also, we investigate the effect of the irregular interval between signals on dividing.

Controlled thermonuclear fusion power apparatus and method

International Nuclear Information System (INIS)

Bussard, R.W.; Coppi, B.

1982-01-01

This invention provides a modular fusion reactor system containing several fusion power cores, each of relatively small size and low cost. Energy from the cores is absorbed in the core structure and within a surrounding blanket, and the cores themselves may be individually removed from the blanket and replaced as they deteriorate from high radiation flux damage

Control of a laser inertial confinement fusion-fission power plant

Science.gov (United States)

Moses, Edward I.; Latkowski, Jeffery F.; Kramer, Kevin J.

2015-10-27

A laser inertial-confinement fusion-fission energy power plant is described. The fusion-fission hybrid system uses inertial confinement fusion to produce neutrons from a fusion reaction of deuterium and tritium. The fusion neutrons drive a sub-critical blanket of fissile or fertile fuel. A coolant circulated through the fuel extracts heat from the fuel that is used to generate electricity. The inertial confinement fusion reaction can be implemented using central hot spot or fast ignition fusion, and direct or indirect drive. The fusion neutrons result in ultra-deep burn-up of the fuel in the fission blanket, thus enabling the burning of nuclear waste. Fuels include depleted uranium, natural uranium, enriched uranium, spent nuclear fuel, thorium, and weapons grade plutonium. LIFE engines can meet worldwide electricity needs in a safe and sustainable manner, while drastically shrinking the highly undesirable stockpiles of depleted uranium, spent nuclear fuel and excess weapons materials.

Magnetic fusion technology

CERN Document Server

Dolan, Thomas J

2014-01-01

Magnetic Fusion Technology describes the technologies that are required for successful development of nuclear fusion power plants using strong magnetic fields. These technologies include: ? magnet systems, ? plasma heating systems, ? control systems, ? energy conversion systems, ? advanced materials development, ? vacuum systems, ? cryogenic systems, ? plasma diagnostics, ? safety systems, and ? power plant design studies. Magnetic Fusion Technology will be useful to students and to specialists working in energy research.

Atomic physics issues in fusion

International Nuclear Information System (INIS)

Post, D.E.

1982-01-01

Atomic physics issues have played a large role in controlled fusion research. A general introduction to the present role of atomic processes in both inertial and magnetic controlled fusion work is presented. (Auth.)

Bringing fusion electric power closer

International Nuclear Information System (INIS)

Kintner, E.

1977-01-01

A review of the controlled fusion research program is given. The tokamak research program is described. Beam injection heating, control systems, and the safety of fusion reactors are topics that are also discussed

v-SNAREs control exocytosis of vesicles from priming to fusion.

Science.gov (United States)

Borisovska, Maria; Zhao, Ying; Tsytsyura, Yaroslav; Glyvuk, Nataliya; Takamori, Shigeo; Matti, Ulf; Rettig, Jens; Südhof, Thomas; Bruns, Dieter

2005-06-15

SNARE proteins (soluble NSF-attachment protein receptors) are thought to be central components of the exocytotic mechanism in neurosecretory cells, but their precise function remained unclear. Here, we show that each of the vesicle-associated SNARE proteins (v-SNARE) of a chromaffin granule, synaptobrevin II or cellubrevin, is sufficient to support Ca(2+)-dependent exocytosis and to establish a pool of primed, readily releasable vesicles. In the absence of both proteins, secretion is abolished, without affecting biogenesis or docking of granules indicating that v-SNAREs are absolutely required for granule exocytosis. We find that synaptobrevin II and cellubrevin differentially control the pool of readily releasable vesicles and show that the v-SNARE's amino terminus regulates the vesicle's primed state. We demonstrate that dynamics of fusion pore dilation are regulated by v-SNAREs, indicating their action throughout exocytosis from priming to fusion of vesicles.

Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.

Science.gov (United States)

Saito, Shoko; Cigdem, Sadik; Okuwaki, Mitsuru; Nagata, Kyosuke

2016-07-01

Nuclear-cytoplasmic transport through nuclear pore complexes is mediated by nuclear transport receptors. Previous reports have suggested that aberrant nuclear-cytoplasmic transport due to mutations or overexpression of nuclear pore complexes and nuclear transport receptors is closely linked to diseases. Nup214, a component of nuclear pore complexes, has been found as chimeric fusion proteins in leukemia. Among various Nup214 fusion proteins, SET-Nup214 and DEK-Nup214 have been shown to be engaged in tumorigenesis, but their oncogenic mechanisms remain unclear. In this study, we examined the functions of the Nup214 fusion proteins by focusing on their effects on nuclear-cytoplasmic transport. We found that SET-Nup214 and DEK-Nup214 interact with exportin-1 (XPO1)/CRM1 and nuclear RNA export factor 1 (NXF1)/TAP, which mediate leucine-rich nuclear export signal (NES)-dependent protein export and mRNA export, respectively. SET-Nup214 and DEK-Nup214 decreased the XPO1-mediated nuclear export of NES proteins such as cyclin B and proteins involved in the NF-κB signaling pathway by tethering XPO1 onto nuclear dots where Nup214 fusion proteins are localized. We also demonstrated that SET-Nup214 and DEK-Nup214 expression inhibited NF-κB-mediated transcription by abnormal tethering of the complex containing p65 and its inhibitor, IκB, in the nucleus. These results suggest that SET-Nup214 and DEK-Nup214 perturb the regulation of gene expression through alteration of the nuclear-cytoplasmic transport system. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Research programme on controlled thermonuclear fusion. Synthesis report 2011

International Nuclear Information System (INIS)

Vaucher, C.; Tran, M. Q.; Villard, L.; Marot, L.

2012-01-01

Since 1978, research on thermonuclear fusion in Switzerland is closely related to the research programme of the European Atomic Energy Community (EURATOM). The Swiss projects tackle aspects of plasma physics and fusion technology. Switzerland participates to the construction and operation of the Joint European Torus (JET), which started operation again in 2011. The International Thermonuclear Experimental Reactor (ITER) is the last step before DEMO, a prototype fusion reactor able to deliver electricity and demonstrate the economic viability of fusion energy. The 'Centre de Recherches en Physique des Plasmas' (CRPP) of the EPFL went on with its participation to the scientific and technological programme of EURATOM. Researches are carried out essentially on 2 sites: (i) at EPFL, where topics dealt with include the physics of magnetic confinement studied using the Variable Configuration Tokamak (TCV), the basic experiment TORPEX, theory and numerical modelling, and the technology of plasma heating and current generation by hyper-frequency waves; (ii) at the Paul Scherrer Institute (PSI), where activities are devoted to superconductivity and structure materials. Thanks to the large flexibility of the TCV design and operation modus, plasmas of different shapes can be created and controlled, what is a very useful option to verify numerical simulation results. Besides, the injection of millimetre waves allows directing the injected power according to specific profiles. In the TCV it could be demonstrated for the first time that the injection of Electronic Cyclotronic Heating (ECH) waves is able to double the frequency of so-called 'Edge Localized Modes' (ELM), reducing by a factor of 2 the energy expelled by each ELM. In particular, it was possible to considerably reduce the statistical dispersion of the repetition frequency of ELM, and to avoid the appearance of gigantic ELM that are particularly harmful for reactor operation. The effect of plasma internal relaxation

Real-Time Plasma Control Tools for Advanced Tokamak Operation

International Nuclear Information System (INIS)

Varandas, C. A. F.; Sousa, J.; Rodrigues, A. P.; Carvalho, B. B.; Fernandes, H.; Batista, A. J.; Cruz, N.; Combo, A.; Pereira, R. C.

2006-01-01

Real-time control will play an important role in the operation and scientific exploitation of the new generation fusion devices. This paper summarizes the real-time systems and diagnostics developed by the Portuguese Fusion Euratom Association based on digital signal processors and field programmable gate arrays

Research program. Controlled thermonuclear fusion. Synthesis report 2013

International Nuclear Information System (INIS)

Villard, L.; Marot, L.

2014-01-01

In 1961, 3 years after the 2 nd International Conference on Peaceful Use of Nuclear Energy, the Research Centre on Plasma Physics (CRPP) was created as a department of the Federal Institute of Technology (EPFL) in Lausanne (Switzerland). From 1979, CRPP collaborates to the European Program on fusion research in the framework of EURATOM. The advantages of fusion are remarkable: the fuel is available in great quantity all over the world; the reactor is intrinsically safe; the reactor material, activated during operation, loses practically all its activity within about 100 years. But the working up of the controlled fusion necessitates extreme technological conditions. The progress realized in the framework of EURATOM has led to the design of the experimental reactor ITER which is being built at Cadarache (France). The future prototype reactor DEMO is foreseen in 2040-2050. In 2013, CRPP participated in the works on ITER in the framework of the Fusion for Energy (F4E) agency. At EPFL the research concerns the physics of the magnetic confinement with experiments on the tokamak TCV (variable configuration tokamak), the numerical simulations, the plasma heating and the generation of current by hyper frequency radio waves. At the Paul Scherrer Institute (PSI), research is devoted to the superconductivity. At the Basel University the studies get on interactions between the plasma and the tokamak walls. A new improved confinement regime, called IN-mode, was discovered on TCV. The theory and numerical simulation group interprets the experimental results and foresees those of futures machines. It requires very high performance computers. The Gyrotron group develops radiofrequency sources in the mm range for heating the TCV plasma as well as for ITER and the Wendelstein-7 stellarator. Concerning superconductivity, tests are conducted at PSI on toroidal cables of ITER. The development of conductors and coils for the DEMO reactor has been pursued. In the context of international

Research program. Controlled thermonuclear fusion. Synthesis report 2015

International Nuclear Information System (INIS)

Villard, L.; Marot, L.; Soom, P.

2016-01-01

In 1961, 3 years after the 2 nd International Conference on Peaceful Use of Nuclear Energy, the Research Centre on Plasma Physics (CRPP) was created as a department of the Federal Institute of Technology (EPFL) in Lausanne (Switzerland). From 1979, CRPP collaborates to the European Program on fusion research in the framework of EURATOM. In 2015 its name was changed to Swiss Plasma Centre (SPC). The advantages of fusion are remarkable: the fuel is available in great quantity all over the world; the reactor is intrinsically safe; the reactor material, activated during operation, loses practically all its activity within about 100 years. But the working up of the controlled fusion necessitates extreme technological conditions. In 1979, the Joint European Torus (JET) began its operation; today it is still the most powerful tokamak in the world, in which an energy yield Q of 0.65 could be obtained. In 2015, the stellarator Wendelstein 7-X (W7X), the largest in the world, was set into operation. The progress realized in the framework of EURATOM has led to the planning of the experimental reactor ITER which is being built at Cadarache (France). ITER is designed to reach a Q-value largely above 1. The future prototype reactor DEMO is foreseen in 2040-2050. It should demonstrate the ability of a fusion reactor to inject permanently electricity into the grid. In 2015, SPC participated in the works on ITER in the framework of the Fusion for Energy (F4E) agency. At EPFL the research concerns the physics of the magnetic confinement with experiments on the tokamak TCV (variable configuration tokamak), the numerical simulations, the plasma heating and the generation of current by hyper frequency radio waves. At the Paul Scherrer Institute (PSI), research is devoted to the superconductivity; at the Basel University the studies get on interactions between the plasma and the tokamak walls. The large flexibility of TCV allows creating and controlling plasmas of different shapes which

Conceptual requirements for large fusion experiment control, data, robotics, and management systems

International Nuclear Information System (INIS)

Gaudreau, M.P.J.; Sullivan, J.D.

1987-05-01

The conceptual system requirements for the control, data, robotics, and project management (CDRM) system for the next generation of fusion experiments are developed by drawing on the success of the Tara control and data system. The requirements are described in terms of an integrated but separable matrix of well-defined interfaces among the various systems and subsystems. The study stresses modularity, performance, cost effectiveness, and exportability

Plasma Physics and Controlled Nuclear Fusion Research. Vol. II. Proceedings of a Conference on Plasma Physics and Controlled Physics Research

International Nuclear Information System (INIS)

1966-01-01

Research on controlled nuclear fusion was first disclosed at the Second United Nations Conference on the Peaceful Uses of Atomic Energy, held at Geneva in 1958. From the information given, it was evident that a better understanding of the behaviour of hot dense plasmas was needed before the goal of economic energy release from nuclear fusion could be reached. The fact that research since then has been most complex and costly has enhanced the desirability of international co-operation and exchange of information and experience. Having organized its First Conference on Plasma Physics and Controlled Nuclear Fusion Research at Salzburg in 1961, the International Atomic Energy Agency again provided the means for such cooperation in organizing its Second Conference on this subject on 6-10 September, 1965, at Culham, Abingdon, Berks, England. The meeting was arranged with the generous help of the United Kingdom Atomic Energy Authority at their Culham Laboratory, where the facilities and assistance of the staff were greatly appreciated. At the meeting, which was attended by 268 participants from 26 member states and three international organizations, significant results from many experiments, including those from the new and larger machines, became available. It has now become feasible to intercorrelate data obtained from a number of similar machines; this has led to a more complete understanding of plasma behaviour. No breakthrough was reported nor had been expected towards the economical release of the energy from fusion, but there was increased understanding of the problems of production, control and containment of high-density and high-temperature plasmas

Reduced optical transmission of SiO2 fibers used in controlled fusion diagnostics

International Nuclear Information System (INIS)

Ramsey, A.T.; Adler, H.G.; Hill, K.W.

1993-02-01

We have subjected a silica core fiber optic cable to 4 years of low-level neutron and gamma radiation from Princeton's TFTR controlled fusion experiment The accumulated dose was 200 Gy. As a result of the radiation, we have measured increased attenuations of 100--300 db/km in the visible part of the spectrum, and a decrease of the numerical aperture. An attempt to decrease this damage by photobleaching failed. We argue that this failure is not unexpected, since the rate of damage is so slow and the time scale so long that the self-annealing process keeps the residual damage at the irreducible level seen in other experiments. The implications of these findings for controlled fusion diagnostics during upcoming experiments with highly reactive deuterium-tritium plasmas are discussed

Demountable toroidal fusion core facility for physics optimization and fusion engineering

International Nuclear Information System (INIS)

Bogart, S.L.; Wagner, C.E.; Krall, N.A.; Dalessandro, J.A.; Weggel, C.F.; Lund, K.O.; Sedehi, S.

1986-01-01

Following a successful compact ignition tokamak (CIT) experiment, a fusion facility will be required for physics optimization (POF) and fusion engineering research (FERF). The POF will address issues such as high-beta operation, current drive, impurity control, and will test geometric and configurational variations such as the spherical torus or the reversed-field pinch (RFP). The FERF will be designed to accumulate rapidly a large neutron dose in prototypical fusion subsystems exposed to radiation. Both facilities will require low-cost replacement cores and rapid replacement times. The Demountable Toroidal Fusion Core (DTFC) facility is designed to fulfill these requirements. It would be a cost-effective stepping stone between the CIT and a demonstration fusion reactor

Control oriented modeling and simulation of the sawtooth instability in nuclear fusion tokamak plasmas

NARCIS (Netherlands)

Witvoet, G.; Westerhof, E.; Steinbuch, M.; Doelman, N.J.; Baar, de M.R.

2009-01-01

Tokamak plasmas in nuclear fusion are subject to various instabilities. A clear example is the sawtooth instability, which has both positive and negative effects on the plasma. To optimize between these effects control of the sawtooth period is necessary. This paper presents a simple control

Synthetic report 2012. Research programme on controlled thermonuclear fusion

International Nuclear Information System (INIS)

Vaucher, C.; Tran, M. Q.; Villard, L.; Marot, L.

2013-01-01

Since 1961, Switzerland participates in the research on thermonuclear fusion thanks to the creation of the Research Centre in Plasma Physics. In 1979 it entered into partnership with the European programme on fusion through its adhesion to EURATOM. The thermonuclear fusion is an interesting energy source because the basic fuel is practically inexhaustible and its use does not release any significant CO 2 quantity and very little radioactive residues. But its working up faces enormous physical and technological difficulties. The International Thermonuclear Reactor (ITER), presently in construction, has to demonstrate the technological feasibility of the controlled fusion. Il will be followed by DEMO, foreseen for 2040-2050, which must guarantee the economical rentability. At CRPP the research projects are partitioned onto several sites: at the Swiss Federal Institute of Technology (EPFL) in Lausanne, they concern the physics of the magnetic confinement with the Variable Geometry Tokamak (TCV), the development of theoretical models and the numerical simulation, the plasma heating and the generation of hyper frequency waves; the Paul Scherrer Institute (PSI) studies the superconductivity and the materials; the interactions between the plasma and the Tokamak walls are studied at the Basel University for the structures of ITER. Thanks to its large flexibility, TCV allows the creation and the control of plasmas of very different forms. The injection system of millimetric waves allows orienting the injected power according to specific profiles. By using the asymmetry of the flow in the toroidal sense, the plasma rotation could be measured with a much better accuracy than before. In TCV, by playing on the form of the plasma, it was possible to strongly reduce the energy quantity which is expelled by the Edge Localized Modes (ELM) onto the wall of the vacuum chamber. The ‘snowflake’ configuration created in TCV allows distributing the ELM energy onto several impact

The European programme for controlled nuclear fusion

International Nuclear Information System (INIS)

This illustrated document is intended for information only and should not be used as a technical reference. The nuclear fusion reactors are presented with the two approaches: magnetic confinement and inertial confinement; are described: the place of fusion in the world energy scene and its importance for Europe, how research is at present organized, and the European programme with this next stage: the JET (Joint European Torus), the largest tokamak machine in Europe

Plasma physics and controlled nuclear fusion research 1990. V. 1

International Nuclear Information System (INIS)

1991-01-01

Volume 1 of the Proceedings of the Thirteenth International Conference on Plasma Physics and Controlled Nuclear Fusion Research contains papers given in two of the sessions: A and E. Session A contains the Artsimovich Memorial Lecture and papers on tokamaks; session E papers on plasma heating and current drive. The titles and authors of each paper are listed in the Contents. Abstracts accompany each paper. Refs, figs and tabs

Safety Impacts of the Actuated Signal Control at Urban Intersections

Directory of Open Access Journals (Sweden)

Sang Hyuk Lee

2016-02-01

Full Text Available To reduce travel time, the actuated signal controls have been implemented at urban intersections. However, the safety impacts of actuated signal controls thus far have rarely been examined. In this assessment of the safety impact of urban intersections with semi-actuated signal controls, the safety performance functions and EB approaches were applied. The semi-actuated signal controls have increased injuries and total crashes in all crash types by around 5.9% and 3.8%, respectively. Regarding the most common crash types, such as angle, sideswipe & rear-end, and head-on crashes, semi-actuated signal controls have been seen to decrease injuries by 7.7%. Total crashes have been reduced by over 9.2% through the use of semi-actuated signal controls. This may be result of optimal signal timings considering traffic conditions during peak time periods. In conclusion, safety impact factors which have been established in this study can be used to improve safety and minimize travel times using semi-actuated signal controls.

BOOK REVIEW: Controlled Fusion and Plasma Physics

Science.gov (United States)

Engelmann, F.

2007-07-01

This new book by Kenro Miyamoto provides an up-to-date overview of the status of fusion research and the important parts of the underlying plasma physics at a moment where, due to the start of ITER construction, an important step in fusion research has been made and many new research workers will enter the field. For them, and also for interested graduate students and physicists in other fields, the book provides a good introduction into fusion physics as, on the whole, the presentation of the material is quite appropriate for getting acquainted with the field on the basis of just general knowledge in physics. There is overlap with Miyamoto's earlier book Plasma Physics for Nuclear Fusion (MIT Press, Cambridge, USA, 1989) but only in a few sections on subjects which have not evolved since. The presentation is subdivided into two parts of about equal length. The first part, following a concise survey of the physics basis of thermonuclear fusion and of plasmas in general, covers the various magnetic configurations studied for plasma confinement (tokamak; reversed field pinch; stellarator; mirror-type geometries) and introduces the specific properties of plasmas in these devices. Plasma confinement in tokamaks is treated in particular detail, in compliance with the importance of this field in fusion research. This includes a review of the ITER concept and of the rationale for the choice of ITER's parameters. In the second part, selected topics in fusion plasma physics (macroscopic instabilities; propagation of waves; kinetic effects such as energy transfer between waves and particles including microscopic instabilities as well as plasma heating and current drive; transport phenomena induced by turbulence) are presented systematically. While the emphasis is on displaying the essential physics, deeper theoretical analysis is also provided here. Every chapter is complemented by a few related problems, but only partial hints for their solution are given. A selection of

development of an electronic vehicular traffic signal controller

African Journals Online (AJOL)

INTRODUCTION ... The SCOOT (Split Cycle Offset Optimization Technique) signal control system implements an adaptive ... An electronic traffic signal controller is basically a sequential machine whose operation can be modeled using finite ...

10th International Conference and School on Plasma Physics and Controlled Fusion. Book of Abstracts

International Nuclear Information System (INIS)

Anon

2004-01-01

About 240 abstracts by Ukrainian and foreign authors submitted to 10-th International Conference and School on Plasma Physics and Controlled fusion have been considered by Conference Program Committee members. All the abstracts have been divided into 8 groups: magnetic confinement systems: stellarators, tokamaks, alternative conceptions; ITER and Fusion reactor aspects; basic plasma physics; space plasma; plasma dynamics and plasma-wall interaction; plasma electronics; low temperature plasma and plasma technologies; plasma diagnostics

A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells

International Nuclear Information System (INIS)

Schnabl, Bernd; Brandl, Katharina; Fink, Marina; Gross, Philipp; Taura, Kojiro; Gaebele, Erwin; Hellerbrand, Claus; Falk, Werner

2008-01-01

Activated hepatic stellate cells (HSCs) play a key role in hepatic fibrogenesis. In injured liver they are the main extracellular matrix protein producing cell type and further perpetuate hepatic injury by secretion of pro-inflammatory mediators. Since LPS-mediated signaling through toll-like receptor 4 (TLR4) has been identified as key fibrogenic signal in HSCs we aimed to test TLR4 as potential target of therapy via ligand-binding soluble receptors. Incubation of human HSCs with a fusion protein between the extracellular domain of TLR4 and MD2 which binds LPS inhibited LPS-induced NFκB and JNK activation. TLR4/MD2 abolished LPS-induced secretion of IL-6, IL-8, MCP1, and RANTES in HSCs. In addition, TLR4/MD2 fused to human IgG-Fc neutralized LPS activity. Since TLR4 mutant mice are resistant to liver fibrosis, the TLR4/MD2 soluble receptor might represent a new therapeutic molecule for liver fibrogenesis in vivo

Distributed traffic signal control using fuzzy logic

Science.gov (United States)

Chiu, Stephen

1992-01-01

We present a distributed approach to traffic signal control, where the signal timing parameters at a given intersection are adjusted as functions of the local traffic condition and of the signal timing parameters at adjacent intersections. Thus, the signal timing parameters evolve dynamically using only local information to improve traffic flow. This distributed approach provides for a fault-tolerant, highly responsive traffic management system. The signal timing at an intersection is defined by three parameters: cycle time, phase split, and offset. We use fuzzy decision rules to adjust these three parameters based only on local information. The amount of change in the timing parameters during each cycle is limited to a small fraction of the current parameters to ensure smooth transition. We show the effectiveness of this method through simulation of the traffic flow in a network of controlled intersections.

Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.

Science.gov (United States)

Suzuki, Kentaro; Adachi, Yasuha; Numata, Tomokazu; Nakada, Shoko; Yanagita, Motoko; Nakagata, Naomi; Evans, Sylvia M; Graf, Daniel; Economides, Aris; Haraguchi, Ryuma; Moon, Anne M; Yamada, Gen

2012-01-01

Sirenomelia, also known as mermaid syndrome, is a developmental malformation of the caudal body characterized by leg fusion and associated anomalies of pelvic/urogenital organs including bladder, kidney, rectum and external genitalia. Most affected infants are stillborn, and the few born alive rarely survive beyond the neonatal period. Despite the many clinical studies of sirenomelia in humans, little is known about the pathogenic developmental mechanisms that cause the complex array of phenotypes observed. Here, we provide new evidences that reduced BMP (Bone Morphogenetic Protein) signaling disrupts caudal body formation in mice and phenocopies sirenomelia. Bmp4 is strongly expressed in the developing caudal body structures including the peri-cloacal region and hindlimb field. In order to address the function of Bmp4 in caudal body formation, we utilized a conditional Bmp4 mouse allele (Bmp4(flox/flox)) and the Isl1 (Islet1)-Cre mouse line. Isl1-Cre is expressed in the peri-cloacal region and the developing hindimb field. Isl1Cre;Bmp4(flox/flox) conditional mutant mice displayed sirenomelia phenotypes including hindlimb fusion and pelvic/urogenital organ dysgenesis. Genetic lineage analyses indicate that Isl1-expressing cells contribute to both the aPCM (anterior Peri-Cloacal Mesenchyme) and the hindlimb bud. We show Bmp4 is essential for the aPCM formation independently with Shh signaling. Furthermore, we show Bmp4 is a major BMP ligand for caudal body formation as shown by compound genetic analyses of Bmp4 and Bmp7. Taken together, this study reveals coordinated development of caudal body structures including pelvic/urogenital organs and hindlimb orchestrated by BMP signaling in Isl1-expressing cells. Our study offers new insights into the pathogenesis of sirenomelia.

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication

Directory of Open Access Journals (Sweden)

Balart Luis A

2010-10-01

Full Text Available Abstract Interferon alpha (IFN-α binds to a cell surface receptor that activates the Jak-Stat signaling pathway. A critical component of this pathway is the translocation of interferon stimulated gene factor 3 (a complex of three proteins Stat1, Stat2 and IRF9 to the nucleus to activate antiviral genes. A stable sub-genomic replicon cell line resistant to IFN-α was developed in which the nuclear translocation of Stat1 and Stat2 proteins was prevented due to the lack of phosphorylation; whereas the nuclear translocation of IRF9 protein was not affected. In this study, we sought to overcome defective Jak-Stat signaling and to induce an antiviral state in the IFN-α resistant replicon cell line by developing a chimera IRF9 protein fused with the trans activating domain (TAD of either a Stat1 (IRF9-S1C or Stat2 (IRF9-S2C protein. We show here that intracellular expression of fusion proteins using the plasmid constructs of either IRF9-S1C or IRF9-S2C, in the IFN-α resistant cells, resulted in an increase in Interferon Stimulated Response Element (ISRE luciferase promoter activity and significantly induced HLA-1 surface expression. Moreover, we show that transient transfection of IRF9-S1C or IRF9-S2C plasmid constructs into IFN-α resistant replicon cells containing sub-genomic HCV1b and HCV2a viruses resulted in an inhibition of viral replication and viral protein expression independent of IFN-α treatment. The results of this study indicate that the recombinant fusion proteins of IRF9-S1C, IRF9-S2C alone, or in combination, have potent antiviral properties against the HCV in an IFN-α resistant cell line with a defective Jak-Stat signaling.

Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.

Directory of Open Access Journals (Sweden)

Kentaro Suzuki

Full Text Available Sirenomelia, also known as mermaid syndrome, is a developmental malformation of the caudal body characterized by leg fusion and associated anomalies of pelvic/urogenital organs including bladder, kidney, rectum and external genitalia. Most affected infants are stillborn, and the few born alive rarely survive beyond the neonatal period. Despite the many clinical studies of sirenomelia in humans, little is known about the pathogenic developmental mechanisms that cause the complex array of phenotypes observed. Here, we provide new evidences that reduced BMP (Bone Morphogenetic Protein signaling disrupts caudal body formation in mice and phenocopies sirenomelia. Bmp4 is strongly expressed in the developing caudal body structures including the peri-cloacal region and hindlimb field. In order to address the function of Bmp4 in caudal body formation, we utilized a conditional Bmp4 mouse allele (Bmp4(flox/flox and the Isl1 (Islet1-Cre mouse line. Isl1-Cre is expressed in the peri-cloacal region and the developing hindimb field. Isl1Cre;Bmp4(flox/flox conditional mutant mice displayed sirenomelia phenotypes including hindlimb fusion and pelvic/urogenital organ dysgenesis. Genetic lineage analyses indicate that Isl1-expressing cells contribute to both the aPCM (anterior Peri-Cloacal Mesenchyme and the hindlimb bud. We show Bmp4 is essential for the aPCM formation independently with Shh signaling. Furthermore, we show Bmp4 is a major BMP ligand for caudal body formation as shown by compound genetic analyses of Bmp4 and Bmp7. Taken together, this study reveals coordinated development of caudal body structures including pelvic/urogenital organs and hindlimb orchestrated by BMP signaling in Isl1-expressing cells. Our study offers new insights into the pathogenesis of sirenomelia.

A Tutorial on Basic Principles of Microwave Reflectometry Applied to Fluctuation Measurements in Fusion Plasmas

International Nuclear Information System (INIS)

Nazikian, R.; Kramer, G.J.; Valeo, E.

2001-01-01

Microwave reflectometry is now routinely used for probing the structure of magnetohydrodynamic and turbulent fluctuations in fusion plasmas. Conditions specific to the core of tokamak plasmas, such as small amplitude of density irregularities and the uniformity of the background plasma, have enabled progress in the quantitative interpretation of reflectometer signals. In particular, the extent of applicability of the 1-D [one-dimensional] geometric optics description of the reflected field is investigated by direct comparison to 1-D full wave analysis. Significant advances in laboratory experiments are discussed which are paving the way towards a thorough understanding of this important measurement technique. Data is presented from the Tokamak Fusion Test Reactor [R. Hawryluk, Plasma Physics and Controlled Fusion 33 (1991) 1509] identifying the validity of the geometric optics description of the scattered field and demonstrating the feasibility of imaging turbulent fluctuations in fusion scale devices

Brushless DC motor control system responsive to control signals generated by a computer or the like

Science.gov (United States)

Packard, Douglas T. (Inventor); Schmitt, Donald E. (Inventor)

1987-01-01

A control system for a brushless DC motor responsive to digital control signals is disclosed. The motor includes a multiphase wound stator and a permanent magnet rotor. The rotor is arranged so that each phase winding, when energized from a DC source, will drive the rotor through a predetermined angular position or step. A commutation signal generator responsive to the shaft position provides a commutation signal for each winding. A programmable control signal generator such as a computer or microprocessor produces individual digital control signals for each phase winding. The control signals and commutation signals associated with each winding are applied to an AND gate for that phase winding. Each gate controls a switch connected in series with the associated phase winding and the DC source so that each phase winding is energized only when the commutation signal and the control signal associated with that phase winding are present. The motor shaft may be advanced one step at a time to a desired position by applying a predetermined number of control signals in the proper sequence to the AND gates and the torque generated by the motor may be regulated by applying a separate control signal to each AND gate which is pulse width modulated to control the total time that each switch connects its associated winding to the DC source during each commutation period.

Demonstrating electromagnetic control of free-surface, liquid-metal flows relevant to fusion reactors

Science.gov (United States)

Hvasta, M. G.; Kolemen, E.; Fisher, A. E.; Ji, H.

2018-01-01

Plasma-facing components (PFC’s) made from solid materials may not be able to withstand the large heat and particle fluxes that will be produced within next-generation fusion reactors. To address the shortcomings of solid PFC’s, a variety of liquid-metal (LM) PFC concepts have been proposed. Many of the suggested LM-PFC designs rely on electromagnetic restraint (Lorentz force) to keep free-surface, liquid-metal flows adhered to the interior surfaces of a fusion reactor. However, there is very little, if any, experimental data demonstrating that free-surface, LM-PFC’s can actually be electromagnetically controlled. Therefore, in this study, electrical currents were injected into a free-surface liquid-metal that was flowing through a uniform magnetic field. The resultant Lorentz force generated within the liquid-metal affected the velocity and depth of the flow in a controllable manner that closely matched theoretical predictions. These results show the promise of electromagnetic control for LM-PFC’s and suggest that electromagnetic control could be further developed to adjust liquid-metal nozzle output, prevent splashing within a tokamak, and alter heat transfer properties for a wide-range of liquid-metal systems.

Fusion energy division computer systems network

International Nuclear Information System (INIS)

Hammons, C.E.

1980-12-01

The Fusion Energy Division of the Oak Ridge National Laboratory (ORNL) operated by Union Carbide Corporation Nuclear Division (UCC-ND) is primarily involved in the investigation of problems related to the use of controlled thermonuclear fusion as an energy source. The Fusion Energy Division supports investigations of experimental fusion devices and related fusion theory. This memo provides a brief overview of the computing environment in the Fusion Energy Division and the computing support provided to the experimental effort and theory research

BOOK REVIEW: Fundamentals of Plasma Physics and Controlled Fusion

Science.gov (United States)

Brambilla, Marco

1998-04-01

Professor Kenro Miyamoto, already well known for his textbook Plasma Physics for Nuclear Fusion (MIT Press, Cambridge, MA, 1976; revised edition 1989), has now published a new book entitled Fundamentals of Plasma Physics and Controlled Fusion (Iwanami Book Service Center, Tokyo, 1997). To a large extent, the new book is a somewhat shortened and well reorganized version of its predecessor. The style, concise and matter of fact, clearly shows the origin of the text in lectures given by the author to graduate students. As announced by the title, the book is divided into two parts: the first part (about 250 pages) is a general introduction to the physics of plasmas, while the second, somewhat shorter, part (about 150 pages), is devoted to a description of the most important experimental approaches to achieving controlled thermonuclear fusion. Even in the first part, moreover, the choice of subjects is consistently oriented towards the needs of fusion research. Thus, the introduction to the behaviour of charged particles (particle motion, collisions, etc.) and to the collective description of plasmas is quite short, although the reader will get a flavour of all the most important topics and will find a number of examples chosen for their relevance to fusion applications (only the presentation of the Vlasov equation, in the second section of Chapter 4, might be criticized as so concise as to be almost misleading, since the difference between microscopic and macroscopic fields is not even mentioned). Considerably more space is devoted to the magnetohydrodynamic (MHD) description of equilibrium and stability. This part includes the solution of the Grad-Shafranov equation for circular tokamaks, a brief discussion of Pfirsch-Schlüter, neoclassical and anomalous diffusion, and two relatively long chapters on the most important ideal and resistive MHD instabilities of toroidal plasmas; drift and ion temperature gradient driven instabilities are also briefly presented. The

LiWall Fusion - The New Concept of Magnetic Fusion

International Nuclear Information System (INIS)

Zakharov, L.E.

2011-01-01

Utilization of the outstanding abilities of a liquid lithium layer in pumping hydrogen isotopes leads to a new approach to magnetic fusion, called the LiWall Fusion. It relies on innovative plasma regimes with low edge density and high temperature. The approach combines fueling the plasma by neutral injection beams with the best possible elimination of outside neutral gas sources, which cools down the plasma edge. Prevention of cooling the plasma edge suppresses the dominant, temperature gradient related turbulence in the core. Such an approach is much more suitable for controlled fusion than the present practice, relying on high heating power for compensating essentially unlimited turbulent energy losses.

Study of the application of advanced control systems to fusion experiments and reactors. Final report

International Nuclear Information System (INIS)

1974-05-01

The work accomplished to date toward the formulation of an advanced control system concept for large-scale magnetically confined thermonuclear fusion devices is summarized. The work was concentrated in three major areas: (1) general control studies and identification of control issues, (2) exploration of possible direct interactions with AEC National Laboratories, and (3) identification of simulation requirements to support control studies. (U.S.)

Fusion reactor design studies

International Nuclear Information System (INIS)

Emmert, G.A.; Kulcinski, G.L.; Santarius, J.F.

1990-01-01

This report discusses the following topics on the ARIES tokamak: systems; plasma power balance; impurity control and fusion ash removal; fusion product ripple loss; energy conversion; reactor fueling; first wall design; shield design; reactor safety; and fuel cost and resources

Plasma Equilibrium Control in Nuclear Fusion Devices 2. Plasma Control in Magnetic Confinement Devices 2.1 Plasma Control in Tokamaks

Science.gov (United States)

Fukuda, Takeshi

The plasma control technique for use in large tokamak devices has made great developmental strides in the last decade, concomitantly with progress in the understanding of tokamak physics and in part facilitated by the substantial advancement in the computing environment. Equilibrium control procedures have thereby been established, and it has been pervasively recognized in recent years that the real-time feedback control of physical quantities is indispensable for the improvement and sustainment of plasma performance in a quasi-steady-state. Further development is presently undertaken to realize the “advanced plasma control” concept, where integrated fusion performance is achieved by the simultaneous feedback control of multiple physical quantities, combined with equilibrium control.

Coatings for fusion reactor environments

International Nuclear Information System (INIS)

Mattox, D.M.

1979-01-01

The internal surfaces of a tokamak fusion reactor control the impurity injection and gas recycling into the fusion plasma. Coating of internal surfaces may provide a desirable and possibly necessary design flexibility for achieving the temperatures, ion densities and containment times necessary for net energy production from fusion reactions to take place. In this paper the reactor environments seen by various componentare reviewed along with possible materials responses. Characteristics of coating-substrate systems, important to fusion applications, are delineated and the present status of coating development for fusion applications is reviewed. Coating development for fusion applications is just beginning and poses a unique and important challenge for materials development

Multi-rate sensor fusion-based adaptive discrete finite-time synergetic control for flexible-joint mechanical systems

International Nuclear Information System (INIS)

Xue Guang-Yue; Ren Xue-Mei; Xia Yuan-Qing

2013-01-01

This paper proposes an adaptive discrete finite-time synergetic control (ADFTSC) scheme based on a multi-rate sensor fusion estimator for flexible-joint mechanical systems in the presence of unmeasured states and dynamic uncertainties. Multi-rate sensors are employed to observe the system states which cannot be directly obtained by encoders due to the existence of joint flexibilities. By using an extended Kalman filter (EKF), the finite-time synergetic controller is designed based on a sensor fusion estimator which estimates states and parameters of the mechanical system with multi-rate measurements. The proposed controller can guarantee the finite-time convergence of tracking errors by the theoretical derivation. Simulation and experimental studies are included to validate the effectiveness of the proposed approach. (general)

Research programme on controlled thermonuclear fusion - Synthesis report 2008

International Nuclear Information System (INIS)

Werthmueller, A.

2009-06-01

Switzerland is associated to the International Thermonuclear Experimental Reactor (ITER) project carried out in the framework of the European Atomic Energy Community (EURATOM). The current stage includes on-site civil engineering works. The Variable Configuration Tokamak (TCV) of the 'Centre de Recherches en Physique des Plasmas' (CRPP) of the EPFL will remain an important recognized research facility until the start of the ITER operation foreseen in 2018. At the European level, the whole fusion research is coordinated and partly financed by the Joint Undertaking Fusion for Energy (JU F4E). The large flexibility of the TCV design and operation modus allow the creation and control of plasmas of various shapes, what is a very useful option to verify the results of numerical simulations. Besides, the hyper-frequency power density injected into the plasma is the highest ever recorded in the world. Research topics studied with the TCV include the stationary regimes in the tokamaks; a plasma current of more than 70 kA could be maintained, what represents an improvement by a factor of 3 to 4 of the confinement quality. For the first time in the world a configuration of the 'snowflake' type could be created and the power density on the wall of the vacuum chamber could be reduced accordingly. Numerical models allowed the analysis of turbulence and heat transport, of the magneto-hydrodynamic stability of the tokamaks and stellarators as well as the optimization of the magnetic confinement. Results concerning the so-called 'saw teeth' instability were experimentally confirmed on the Joint European Torus (JET). Theoretical researches were carried out on the fluctuations, turbulence and transport phenomena in the magnetized toric plasmas. At the Paul Scherrer Institute (PSI) the effect of the fast neutrons emitted by the fusion reactions on the walls of the fusion reactors was investigated. Irradiation simulations were carried out by means of the Swiss Spallation Neutron Source

Sensor Fusion Techniques for Phased-Array Eddy Current and Phased-Array Ultrasound Data

Energy Technology Data Exchange (ETDEWEB)

Arrowood, Lloyd F. [Y-12 National Security Complex, Oak Ridge, TN (United States)

2018-03-15

Sensor (or Data) fusion is the process of integrating multiple data sources to produce more consistent, accurate and comprehensive information than is provided by a single data source. Sensor fusion may also be used to combine multiple signals from a single modality to improve the performance of a particular inspection technique. Industrial nondestructive testing may utilize multiple sensors to acquire inspection data depending upon the object under inspection and the anticipated types of defects that can be identified. Sensor fusion can be performed at various levels of signal abstraction with each having its strengths and weaknesses. A multimodal data fusion strategy first proposed by Heideklang and Shokouhi that combines spatially scattered detection locations to improve detection performance of surface-breaking and near-surface cracks in ferromagnetic metals is shown using a surface inspection example and is then extended for volumetric inspections. Utilizing data acquired from an Olympus Omniscan MX2 from both phased array eddy current and ultrasound probes on test phantoms, single and multilevel fusion techniques are employed to integrate signals from the two modalities. Preliminary results demonstrate how confidence in defect identification and interpretation benefit from sensor fusion techniques. Lastly, techniques for integrating data into radiographic and volumetric imagery from computed tomography are described and results are presented.

A measurement fusion method for nonlinear system identification using a cooperative learning algorithm.

Science.gov (United States)

Xia, Youshen; Kamel, Mohamed S

2007-06-01

Identification of a general nonlinear noisy system viewed as an estimation of a predictor function is studied in this article. A measurement fusion method for the predictor function estimate is proposed. In the proposed scheme, observed data are first fused by using an optimal fusion technique, and then the optimal fused data are incorporated in a nonlinear function estimator based on a robust least squares support vector machine (LS-SVM). A cooperative learning algorithm is proposed to implement the proposed measurement fusion method. Compared with related identification methods, the proposed method can minimize both the approximation error and the noise error. The performance analysis shows that the proposed optimal measurement fusion function estimate has a smaller mean square error than the LS-SVM function estimate. Moreover, the proposed cooperative learning algorithm can converge globally to the optimal measurement fusion function estimate. Finally, the proposed measurement fusion method is applied to ARMA signal and spatial temporal signal modeling. Experimental results show that the proposed measurement fusion method can provide a more accurate model.

Introduction to controlled thermonuclear fusion

International Nuclear Information System (INIS)

Assis, A.S. de; Rapozo, C.C.

1988-07-01

During many centuries the origin of the enormous power output of the sun remained as a mistery. However, in this century, the physicists have discovered that stars get their energy from the fusion of light nuclei (such as deuterons and tritons), and the Einstein's equation, AE = (Am)c 2 , was the way to explain this physical process. (author)

Introduction to Nuclear Fusion Power and the Design of Fusion Reactors. An Issue-Oriented Module.

Science.gov (United States)

Fillo, J. A.

This three-part module focuses on the principles of nuclear fusion and on the likely nature and components of a controlled-fusion power reactor. The physical conditions for a net energy release from fusion and two approaches (magnetic and inertial confinement) which are being developed to achieve this goal are described. Safety issues associated…

Reaching to a featured formula to deduce the energy of the heaviest particles producing from the controlled thermonuclear fusion reactions

Science.gov (United States)

Majeed, Raad H.; Oudah, Osamah N.

2018-05-01

Thermonuclear fusion reaction plays an important role in developing and construction any power plant system. Studying the physical behavior for the possible mechanism governed energies released by the fusion products to precise understanding the related kinematics. In this work a theoretical formula controlled the general applied thermonuclear fusion reactions is achieved to calculating the fusion products energy depending upon the reactants physical properties and therefore, one can calculate other parameters governed a given reaction. By using this formula, the energy spectrum of 4He produced from T-3He fusion reaction has been sketched with respect to reaction angle and incident energy ranged from (0.08-0.6) MeV.

LLL magnetic fusion research: the first 25 years

International Nuclear Information System (INIS)

Post, R.F.

1978-01-01

From its inception, the Laboratory has supported research directed at tapping controlled fusion. Our magnetic fusion energy program--now one of the major elements of the national fusion energy research effort--dates back to the Laboratory's founding in 1952. This article reviews the program's beginnings, progress, and present status in terms of its ultimate goal: to demonstrate a practical and economical means of generating power from controlled fusion reactions

Pedestrian Friendly Traffic Signal Control.

Science.gov (United States)

2016-01-01

This project continues research aimed at real-time detection and use of pedestrian : traffic flow information to enhance adaptive traffic signal control in urban areas : where pedestrian traffic is substantial and must be given appropriate attention ...

Introduction to plasma physics and controlled fusion

CERN Document Server

Chen, Francis F

1984-01-01

This complete introduction to plasma physics and controlled fusion by one of the pioneering scientists in this expanding field offers both a simple and intuitive discussion of the basic concepts of this subject and an insight into the challenging problems of current research. In a wholly lucid manner the work covers single-particle motions, fluid equations for plasmas, wave motions, diffusion and resistivity, Landau damping, plasma instabilities and nonlinear problems. For students, this outstanding text offers a painless introduction to this important field; for teachers, a large collection of problems; and for researchers, a concise review of the fundamentals as well as original treatments of a number of topics never before explained so clearly. This revised edition contains new material on kinetic effects, including Bernstein waves and the plasma dispersion function, and on nonlinear wave equations and solitons.

Fusion, magnetic confinement

International Nuclear Information System (INIS)

Berk, H.L.

1992-01-01

An overview is presented of the principles of magnetic confinement of plasmas for the purpose of achieving controlled fusion conditions. Sec. 1 discusses the different nuclear fusion reactions which can be exploited in prospective fusion reactors and explains why special technologies need to be developed for the supply of tritium or 3 He, the probable fuels. In Sec. 2 the Lawson condition, a criterion that is a measure of the quality of confinement relative to achieving fusion conditions, is explained. In Sec. 3 fluid equations are used to describe plasma confinement. Specific confinement configurations are considered. In Sec. 4 the orbits of particle sin magneti and electric fields are discussed. In Sec. 5 stability considerations are discussed. It is noted that confinement systems usually need to satisfy stability constraints imposed by ideal magnetohydrodynamic (MHD) theory. The paper culminates with a summary of experimental progress in magnetic confinement. Present experiments in tokamaks have reached the point that the conditions necessary to achieve fusion are being satisfied

Fusion spectroscopy

International Nuclear Information System (INIS)

Peacock, N.J.

1995-09-01

This article traces developments in the spectroscopy of high temperature laboratory plasma used in controlled fusion research from the early 1960's until the present. These three and a half decades have witnessed many orders of magnitude increase in accessible plasma parameters such as density and temperature as well as particle and energy confinement timescales. Driven by the need to interpret the radiation in terms of the local plasma parameters, the thrust of fusion spectroscopy has been to develop our understanding of (i) the atomic structure of highly ionised atoms, usually of impurities in the hydrogen isotope fuel; (ii) the atomic collision rates and their incorporation into ionization structure and emissivity models that take into account plasma phenomena like plasma-wall interactions, particle transport and radiation patterns; (iii) the diagnostic applications of spectroscopy aided by increasingly sophisticated characterisation of the electron fluid. These topics are discussed in relation to toroidal magnetically confined plasmas, particularly the Tokamak which appears to be the most promising approach to controlled fusion to date. (author)

Tritium control and capture in salt-cooled fission and fusion reactors: Status, challenges, and path forward

International Nuclear Information System (INIS)

Forsberg, Charles W.; Lam, Stephen; Carpenter, David M.; Whyte, Dennis G.; Scarlat, Raluca

2017-01-01

Three advanced nuclear power systems use liquid salt coolants that generate tritium and thus face the common challenges of containing and capturing tritium to prevent its release to the environment. The Fluoride-salt-cooled High-temperature Reactor (FHR) uses clean fluoride salt coolants and the same graphite-matrix coated-particle fuel as high-temperature gas-cooled reactors. Molten salt reactors (MSRs) dissolve the fuel in a fluoride or chloride salt with release of fission product tritium into the salt. In most FHR and MSR systems, the base-line salts contain lithium where isotopically separated "7Li is proposed to minimize tritium production from neutron interactions with the salt. The Chinese Academy of Science plans to start operation of a 2-MWt molten salt test reactor by 2020. For high-magnetic-field fusion machines, the use of lithium enriched in "6Li is proposed to maximize tritium generation the fuel for a fusion machine. Advances in superconductors that enable higher power densities may require the use of molten lithium salts for fusion blankets and as coolants. Recent technical advances in these three reactor classes have resulted in increased government and private interest and the beginning of a coordinated effort to address the tritium control challenges in 700 °C liquid salt systems. We describe characteristics of salt-cooled fission and fusion machines, the basis for growing interest in these technologies, tritium generation in molten salts, the environment for tritium capture, models for high-temperature tritium transport in salt systems, alternative strategies for tritium control, and ongoing experimental work. Several methods to control tritium appear viable. Finally, limited experimental data is the primary constraint for designing efficient cost-effective methods of tritium control.

Control of striatal signaling by G protein regulators

Directory of Open Access Journals (Sweden)

Keqiang eXie

2011-08-01

Full Text Available Signaling via heterotrimeric G proteins plays a crucial role in modulating the responses of striatal neurons that ultimately shape core behaviors mediated by the basal ganglia circuitry, such as reward valuation, habit formation and movement coordination. Activation of G-protein-coupled receptors (GPCRs by extracellular signals activates heterotrimeric G proteins by promoting the binding of GTP to their α subunits. G proteins exert their effects by influencing the activity of key effector proteins in this region, including ion channels, second messenger enzymes and protein kinases. Striatal neurons express a staggering number of GPCRs whose activation results in the engagement of downstream signaling pathways and cellular responses with unique profiles but common molecular mechanisms. Studies over the last decade have revealed that the extent and duration of GPCR signaling are controlled by a conserved protein family named Regulator of G protein Signaling (RGS. RGS proteins accelerate GTP hydrolysis by the α subunits of G proteins, thus promoting deactivation of GPCR signaling. In this review, we discuss the progress made in understanding the roles of RGS proteins in controlling striatal G protein signaling and providing integration and selectivity of signal transmission. We review evidence on the formation of a macromolecular complex between RGS proteins and other components of striatal signaling pathways, their molecular regulatory mechanisms and impacts on GPCR signaling in the striatum obtained from biochemical studies and experiments involving genetic mouse models. Special emphasis is placed on RGS9-2, a member of the RGS family that is highly enriched in the striatum and plays critical roles in drug addiction and motor control.

Contributions to the 7th International Conference on plasma surface interactions in controlled fusion devices

International Nuclear Information System (INIS)

1986-01-01

The report contains three papers presented in the 7th International Conference on plasma surface interactions in controlled fusion devices held in Princeton (USA) 5-9 May 1986, all referred to the FT Tokamak

Research programme on controlled thermonuclear fusion. Synthesis report 2011; Programme de recherche Fusion thermonucleaire controlee. Rapport de synthese 2011

Energy Technology Data Exchange (ETDEWEB)

Vaucher, C. [Secretariat d' Etat a l' education et a la recherche, Berne (Switzerland); Tran, M. Q.; Villard, L. [Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Marot, L. [University of Basel, Basel (Switzerland)

2012-07-01

Since 1978, research on thermonuclear fusion in Switzerland is closely related to the research programme of the European Atomic Energy Community (EURATOM). The Swiss projects tackle aspects of plasma physics and fusion technology. Switzerland participates to the construction and operation of the Joint European Torus (JET), which started operation again in 2011. The International Thermonuclear Experimental Reactor (ITER) is the last step before DEMO, a prototype fusion reactor able to deliver electricity and demonstrate the economic viability of fusion energy. The 'Centre de Recherches en Physique des Plasmas' (CRPP) of the EPFL went on with its participation to the scientific and technological programme of EURATOM. Researches are carried out essentially on 2 sites: (i) at EPFL, where topics dealt with include the physics of magnetic confinement studied using the Variable Configuration Tokamak (TCV), the basic experiment TORPEX, theory and numerical modelling, and the technology of plasma heating and current generation by hyper-frequency waves; (ii) at the Paul Scherrer Institute (PSI), where activities are devoted to superconductivity and structure materials. Thanks to the large flexibility of the TCV design and operation modus, plasmas of different shapes can be created and controlled, what is a very useful option to verify numerical simulation results. Besides, the injection of millimetre waves allows directing the injected power according to specific profiles. In the TCV it could be demonstrated for the first time that the injection of Electronic Cyclotronic Heating (ECH) waves is able to double the frequency of so-called 'Edge Localized Modes' (ELM), reducing by a factor of 2 the energy expelled by each ELM. In particular, it was possible to considerably reduce the statistical dispersion of the repetition frequency of ELM, and to avoid the appearance of gigantic ELM that are particularly harmful for reactor operation. The effect of plasma

Genomic instability and telomere fusion of canine osteosarcoma cells.

Directory of Open Access Journals (Sweden)

Junko Maeda

Full Text Available Canine osteosarcoma (OSA is known to present with highly variable and chaotic karyotypes, including hypodiploidy, hyperdiploidy, and increased numbers of metacentric chromosomes. The spectrum of genomic instabilities in canine OSA has significantly augmented the difficulty in clearly defining the biological and clinical significance of the observed cytogenetic abnormalities. In this study, eight canine OSA cell lines were used to investigate telomere fusions by fluorescence in situ hybridization (FISH using a peptide nucleotide acid probe. We characterized each cell line by classical cytogenetic studies and cellular phenotypes including telomere associated factors and then evaluated correlations from this data. All eight canine OSA cell lines displayed increased abnormal metacentric chromosomes and exhibited numerous telomere fusions and interstitial telomeric signals. Also, as evidence of unstable telomeres, colocalization of γ-H2AX and telomere signals in interphase cells was observed. Each cell line was characterized by a combination of data representing cellular doubling time, DNA content, chromosome number, metacentric chromosome frequency, telomere signal level, cellular radiosensitivity, and DNA-PKcs protein expression level. We have also studied primary cultures from 10 spontaneous canine OSAs. Based on the observation of telomere aberrations in those primary cell cultures, we are reasonably certain that our observations in cell lines are not an artifact of prolonged culture. A correlation between telomere fusions and the other characteristics analyzed in our study could not be identified. However, it is important to note that all of the canine OSA samples exhibiting telomere fusion utilized in our study were telomerase positive. Pending further research regarding telomerase negative canine OSA cell lines, our findings may suggest telomere fusions can potentially serve as a novel marker for canine OSA.

Digital signal processing in power system protection and control

CERN Document Server

Rebizant, Waldemar; Wiszniewski, Andrzej

2011-01-01

Digital Signal Processing in Power System Protection and Control bridges the gap between the theory of protection and control and the practical applications of protection equipment. Understanding how protection functions is crucial not only for equipment developers and manufacturers, but also for their users who need to install, set and operate the protection devices in an appropriate manner. After introductory chapters related to protection technology and functions, Digital Signal Processing in Power System Protection and Control presents the digital algorithms for signal filtering, followed

Plasma physics for controlled fusion

International Nuclear Information System (INIS)

Miyamoto, K.

2010-01-01

The primary objective of this lecture note is to present the theories and experiments of plasma physics for recent activities of controlled fusion research for graduate and senior undergraduate students. Chapters 1-6 describe the basic knowledge of plasma and magnetohydrodynamics (MHD). MHD instabilities limit the beta ratio (ratio of plasma pressure to magnetic pressure) of confined plasma. Chapters 7-9 provide the kinetic theory of hot plasma and discuss the wave heating and non-inductive current drive. The dispersion relation derived by the kinetic theory are used to discuss plasma waves and perturbed modes. Landau damping is the essential mechanism of plasma heating and the stabilization of perturbation. Landau inverse damping brings the amplification of waves and the destabilization of perturbed modes. Chapter 10 explains the plasma transport due to turbulence, which is the most important and challenging subject for plasma confinement. Theories and simulations including subject of zonal flow are introduced. Chapters 11, 12 and 13 describe the recent activities of tokamak including ITER as well as spherical tokamak, reversed field pinch (RFP) and stellarator including quasi-symmetric configurations. Emphasis has been given to tokamak research since it made the most remarkable progress and the construction phase of 'International Tokamak Experimental Reactor' called ITER has already started. (author)

Rapid Elimination of the Persistent Synergid through a Cell Fusion Mechanism

KAUST Repository

Maruyama, Daisuke

2015-05-01

In flowering plants, fertilization-dependent degeneration of the persistent synergid cell ensures one-on-one pairings of male and female gametes. Here, we report that the fusion of the persistent synergid cell and the endosperm selectively inactivates the persistent synergid cell in Arabidopsis thaliana. The synergid-endosperm fusion causes rapid dilution of pre-secreted pollen tube attractant in the persistent synergid cell and selective disorganization of the synergid nucleus during the endosperm proliferation, preventing attractions of excess number of pollen tubes (polytubey). The synergid-endosperm fusion is induced by fertilization of the central cell, while the egg cell fertilization predominantly activates ethylene signaling, an inducer of the synergid nuclear disorganization. Therefore, two female gametes (the egg and the central cell) control independent pathways yet coordinately accomplish the elimination of the persistent synergid cell by double fertilization. Two female gametes (the egg cell and the central cell) in flowering plants coordinately prevent attractions of excess number of pollen tubes via two mechanisms to inactivate persistent synergid cell. © 2015 Elsevier Inc.

50 years of controlled nuclear fusion in the European Union

International Nuclear Information System (INIS)

Vandenplas, P.; Wolf, G.H.

2008-01-01

The author presents the history of fusion energy since its official birth in 1955 during the first conference on the peaceful uses of atomic energy to the expectations put on the ITER project. Nuclear fusion became a major component of the newly created European Atomic Energy Community (EURATOM). The milestones that were: magnetic mirror machines, pinch versions, stellarators and tokamaks are examined. The construction of the first fusion machines were decisive and gave fusion energy enough momentum to overcome greater and greater technological difficulties. At the scale of the world, major machines that were built like TFTR, Princeton (1974), JET, Culham (1977) or JT60, Tokai (1977), appear like a scientific and necessary strategy towards the demonstration reactor. The ITER project is detailed

Signal differentiation in position tracking control of dc motors

International Nuclear Information System (INIS)

Beltran-Carbajal, F; Valderrabano-Gonzalez, A; Rosas-Caro, J C

2015-01-01

An asymptotic differentiation approach with respect to time is used for on-line estimation of velocity and acceleration signals in controlled dc motors. The attractive feature of this differentiator of signals is that it does not require any system mathematical model, which allows its use in engineering systems that require the signal differentiation for its control, identification, fault detection, among other applications. Moreover, it is shown that the differentiation approach can be applied for output signals showing a chaotic behavior. In addition a differential flatness control scheme with additional integral compensation of the output error is proposed for tracking tasks of position reference trajectories for direct current electric motors using angular position measurements only

Health physics in fusion reactor design

International Nuclear Information System (INIS)

Wong, K.Y.; Dinner, P.J.

1984-06-01

Experience in the control of tritium exposures to workers and the public gained through the design and operation of Ontario Hydro's nuclear stations has been applied to fusion projects and to design studies on emerging fusion reactor concepts. Ontario Hydro performance in occupational tritium exposure control and environmental impact is reviewed. Application of tritium control technologies and dose management methodology during facility design is highlighted

History and status of magnetic fusion research; Evolution et statut des recherches sur la fusion controlee

Energy Technology Data Exchange (ETDEWEB)

Jacquinot, J. [CEA Saclay, Cabinet du Haut Commissaire, 91 - Gif-sur-Yvette (France)

2008-02-15

Ever since the understanding of the basic process which powers the stars has been elucidated, humanity has been dreaming to master controlled fusion for peaceful purposes. Controlled fusion in a steady state regime must use magnetic confinement of a gas (plasma) heated up to 150 millions degrees. Physics and technology involved in such a state are extremely complex and went through many up and down phases. Nevertheless, the overall progress has been spectacular and a significant amount of energy could be produced in a well controlled manner. On this basis, an international organisation of unprecedented magnitude involving 34 countries has started working in Cadarache for the construction of the ITER project. It aims at the scientific demonstration of controlled fusion at the level of 500 MW and a power gain of 10. (author)

American research programs on controlled thermonuclear fusion

International Nuclear Information System (INIS)

Anon.

1978-01-01

At a time when the site of the European JET project has been decided, this study proposes to highlight the American effort in this field over the last five years. The Federal Civil Research and Development budget assigned to Energy has been multiplied by 6.3 and inside this budget the portion allocated to fusion has been multiplied by a factor of 6, in value. Two avenues have been explored; magnetic confinement and inertial confinement but one reaction only has been considered, namely D + T fusion. In magnetic confinement, the first operational reactor is being contemplated for around the year 2012. Three technologies have been explored in inertial confinement: by laser beams, electron beams and ion beams [fr

Japanese fusion research

International Nuclear Information System (INIS)

Uchida, T.

1987-01-01

The Japan experience during thirty years in nuclear fusion research is reported, after attending the 1st Geneva Conference in 1955, Osaka University, immedeately began linear pinch study using capacitor bank discharge. Subsequently to his trial several groups were organized to ward fusion R and D at universities in Tokyo, Nagoya, Kyoto, Sendai and son on. Based upon the recommendation of Japan Science Council, Institut of Plasma Physics (IPP) was established at Nagoya University in 1961 When the 1st International Conference on Plasma Physics and Controlled Nuclear Fusion Research was held in Saltzburg. The gloomy Bohm barrier had stood in front of many of experiments at that time. (author) [pt

Net analyte signal based statistical quality control

NARCIS (Netherlands)

Skibsted, E.T.S.; Boelens, H.F.M.; Westerhuis, J.A.; Smilde, A.K.; Broad, N.W.; Rees, D.R.; Witte, D.T.

2005-01-01

Net analyte signal statistical quality control (NAS-SQC) is a new methodology to perform multivariate product quality monitoring based on the net analyte signal approach. The main advantage of NAS-SQC is that the systematic variation in the product due to the analyte (or property) of interest is

Peaceful Uses of Fusion

Science.gov (United States)

Teller, E.

1958-07-03

Applications of thermonuclear energy for peaceful and constructive purposes are surveyed. Developments and problems in the release and control of fusion energy are reviewed. It is pointed out that the future of thermonuclear power reactors will depend upon the construction of a machine that produces more electric energy than it consumes. The fuel for thermonuclear reactors is cheap and practically inexhaustible. Thermonuclear reactors produce less dangerous radioactive materials than fission reactors and, when once brought under control, are not as likely to be subject to dangerous excursions. The interaction of the hot plasma with magnetic fields opens the way for the direct production of electricity. It is possible that explosive fusion energy released underground may be harnessed for the production of electricity before the same feat is accomplished in controlled fusion processes. Applications of underground detonations of fission devices in mining and for the enhancement of oil flow in large low-specific-yield formations are also suggested.

Evaluation of efficacy of a new hybrid fusion device: a randomized, two-centre controlled trial.

Science.gov (United States)

Siewe, Jan; Bredow, Jan; Oppermann, Johannes; Koy, Timmo; Delank, Stefan; Knoell, Peter; Eysel, Peer; Sobottke, Rolf; Zarghooni, Kourosh; Röllinghoff, Marc

2014-09-05

The 360° fusion of lumbar segments is a common and well-researched therapy to treat various diseases of the spine. But it changes the biomechanics of the spine and may cause adjacent segment disease (ASD). Among the many techniques developed to avoid this complication, one appears promising. It combines a rigid fusion with a flexible pedicle screw system (hybrid instrumentation, "topping off"). However, its clinical significance is still uncertain due to the lack of conclusive data. The study is a randomized, therapy-controlled, two-centre trial conducted in a clinical setting at two university hospitals. If they meet the criteria, outpatients presenting with degenerative disc disease, facet joint arthrosis or spondylolisthesis will be included in the study and randomized into two groups: a control group undergoing conventional fusion surgery (PLIF - posterior lumbar intervertebral fusion), and an intervention group undergoing fusion surgery using a new flexible pedicle screw system (PLIF + "topping off"), which was brought on the market in 2013. Follow-up examination will take place immediately after surgery, after 6 weeks and after 6, 12, 24 and 36 months. An ongoing assessment will be performed every year.Outcome measurements will include quality of life and pain assessments using validated questionnaires (ODI - Ostwestry Disability Index, SF-36™ - Short Form Health Survey 36, COMI - Core Outcome Measure Index). In addition, clinical and radiologic ASD, sagittal balance parameters and duration of work disability will be assessed. Inpatient and 6-month mortality, surgery-related data (e.g., intraoperative complications, blood loss, length of incision, surgical duration), postoperative complications (e.g. implant failure), adverse events, and serious adverse events will be monitored and documented throughout the study. New hybrid "topping off" systems might improve the outcome of lumbar spine fusion. But to date, there is a serious lack of and a great need

Coatings for laser fusion

International Nuclear Information System (INIS)

Lowdermilk, W.H.

1981-01-01

Optical coatings are used in lasers systems for fusion research to control beam propagation and reduce surface reflection losses. The performance of coatings is important in the design, reliability, energy output, and cost of the laser systems. Significant developments in coating technology are required for future lasers for fusion research and eventual power reactors

Plasma physics and controlled nuclear fusion

International Nuclear Information System (INIS)

Sato, Tetsuya

1993-05-01

The report contains the proceedings of a conference on plasma physics. A fraction of topics included MHD instabilities, magnetic confinement and plasma heating in the field of fusion plasmas, in 8 papers falling in the INIS scope have been abstracted and indexed for the INIS database. (K.A.)

A vision fusion treatment system based on ATtiny26L

Science.gov (United States)

Zhang, Xiaoqing; Zhang, Chunxi; Wang, Jiqiang

2006-11-01

Vision fusion treatment is an important and effective project to strabismus children. The vision fusion treatment system based on the principle for eyeballs to follow the moving visual survey pole is put forward first. In this system the original position of visual survey pole is about 35 centimeters far from patient's face before its moving to the middle position between the two eyeballs. The eyeballs of patient will follow the movement of the visual survey pole. When they can't follow, one or two eyeballs will turn to other position other than the visual survey pole. This displacement is recorded every time. A popular single chip microcomputer ATtiny26L is used in this system, which has a PWM output signal to control visual survey pole to move with continuously variable speed. The movement of visual survey pole accords to the modulating law of eyeballs to follow visual survey pole.

Application of controlled thermonuclear reactor fusion energy for food production

International Nuclear Information System (INIS)

Dang, V.D.; Steinberg, M.

1975-06-01

Food and energy shortages in many parts of the world in the past two years raise an immediate need for the evaluation of energy input in food production. The present paper investigates systematically (1) the energy requirement for food production, and (2) the provision of controlled thermonuclear fusion energy for major energy intensive sectors of food manufacturing. Among all the items of energy input to the ''food industry,'' fertilizers, water for irrigation, food processing industries, such as beet sugar refinery and dough making and single cell protein manufacturing, have been chosen for study in detail. A controlled thermonuclear power reactor was used to provide electrical and thermal energy for all these processes. Conceptual design of the application of controlled thermonuclear power, water and air for methanol and ammonia synthesis and single cell protein production is presented. Economic analysis shows that these processes can be competitive. (auth)

Intersection signal control multi-objective optimization based on genetic algorithm

OpenAIRE

Zhanhong Zhou; Ming Cai

2014-01-01

A signal control intersection increases not only vehicle delay, but also vehicle emissions and fuel consumption in that area. Because more and more fuel and air pollution problems arise recently, an intersection signal control optimization method which aims at reducing vehicle emissions, fuel consumption and vehicle delay is required heavily. This paper proposed a signal control multi-object optimization method to reduce vehicle emissions, fuel consumption and vehicle delay simultaneously at ...

Programs for control of an analog-signal switching network

International Nuclear Information System (INIS)

D'Ottavio, T.; Enriquez, R.; Katz, R.; Skelly, J.

1989-01-01

A suite of programs has been developed to control the network of analog-signal switching multiplexers in the AGS complex. The software is driven by a relational database which describes the architecture of the multiplexer tree and the set of available analog signals. Signals are routed through a three-layer multiplexer tree, to be made available at four consoles each with three 4-trace oscilloscopes. A menu-structured operator interface program is available at each console, to accept requests to route any available analog signal to any of that console's 12 oscilloscope traces. A common routing-server program provides automatic routing-server program provides automatic routing of requested signals through the layers of multiplexers, maintaining a reservation database to denote free and in-use trunks. Expansion of the analog signal system is easily accommodated in software by adding new signals, trunks, multiplexers, or consoles to the database. Programmatic control of the triggering signals for each of the oscilloscopes is also provided. 3 refs., 4 figs., 3 tabs

The IGNITEX fusion project

International Nuclear Information System (INIS)

Carrera, R.

1987-01-01

The author discusses the recently proposed fusion ignition experiment, IGNITEX. He emphasizes the basic ideas of this concept rather than the specific details of the physics and engineering aspects of the experiment. This concept is a good example of the importance of maintaining an adequate balance between the basic scientific progress in fusion physics and the new technologies that are becoming available in order to make fusion work. The objective of the IGNITEX project is to produce and control ignited plasmas for scientific study in the simplest and least expensive way possible. Being able to study this not-yet-produced regime of plasma operation is essential to fusion research. Two years after the fission nuclear reaction was discovered, a non-self-sustained fission reaction was produced in a laboratory, and in one more year a self-sustained reaction was achieved at the University of Chicago. However, after almost forty years of fusion research, a self-sustained fusion reaction has yet not been produced in a laboratory experiment. This fact indicates the greater difficulty of the fusion experiment. Because of the difficulty involved in the production of a self-sustained fusion reaction, it is necessary to propose such an experiment with maximum ignition margins, maximum simplicity, and minimum financial risk

Continuous residual reinforcement learning for traffic signal control optimization

NARCIS (Netherlands)

Aslani, Mohammad; Seipel, Stefan; Wiering, Marco

2018-01-01

Traffic signal control can be naturally regarded as a reinforcement learning problem. Unfortunately, it is one of the most difficult classes of reinforcement learning problems owing to its large state space. A straightforward approach to address this challenge is to control traffic signals based on

Fusion rings and fusion ideals

DEFF Research Database (Denmark)

Andersen, Troels Bak

by the so-called fusion ideals. The fusion rings of Wess-Zumino-Witten models have been widely studied and are well understood in terms of precise combinatorial descriptions and explicit generating sets of the fusion ideals. They also appear in another, more general, setting via tilting modules for quantum......This dissertation investigates fusion rings, which are Grothendieck groups of rigid, monoidal, semisimple, abelian categories. Special interest is in rational fusion rings, i.e., fusion rings which admit a finite basis, for as commutative rings they may be presented as quotients of polynomial rings...

An electrolytic route to fusion?

International Nuclear Information System (INIS)

Anon.

1992-01-01

A patent has been granted by the Swedish Patent Authority for a new process to initiate and control energy generation through fusion reactions of hydrogen. According to the patent-holder, the Swedish company AB Technology Development, the fusion power process could be available for commercial applications within 4-5 years if laboratory and pilot plant tests prove successful. The new process employs a high voltage discharge in heavy water to create conditions under which, according to the patent holder, a high probability of fusion is achieved without the extraordinary high temperatures required in a conventional fusion reactor. (author)

Multilayer mirror based monitors for impurity controls in large fusion reactor type devices

International Nuclear Information System (INIS)

Regan, S.P.; May, M.J.; Soukhanovskii, V.; Finkenthal, M.; Moos, H.W.

1995-01-01

Multilayer Mirror (MLM) based monitors are compact, high throughput diagnostics capable of extracting XUV emissions (the wavelength range including the soft-x-ray and the extreme ultraviolet, 10 angstrom to 304 angstrom) of impurities from the harsh environment of large fusion reactor type devices. For several years the Plasma Spectroscopy Group at Johns Hopkins University has investigated the application of MLM based XUV spectroscopic diagnostics for magnetically confined fusion plasmas. MLM based monitors have been constructed for and extensively used on DIII-D, Alcator C-mod, TEXT, Phaedrus-T, and CDX-U tokamaks to study the impurity behavior of elements ranging from He to Mo. On ITER MLM based devices would be used to monitor the spectral line emissions from Li I-like to F I-like charge states of Fe, Cr, and Ni, as well as extractors for the bands of emissions from high Z elements such as Mo or W for impurity controls of the fusion plasma. In addition to monitoring the impurity emissions from the main plasma, MLM based devices can also be adapted for radiation measurements of low Z elements in the divertor. The concepts and designs of these MLM based monitors for impurity controls in ITER will be presented. The results of neutron irradiation experiments of the MLMs performed in the Los Alamos Spallation Radiation Effects Facility (LASREF) at the Los Alamos National Laboratory will also be discussed. These preliminary neutron exposure studies show that the dispersive and reflective qualities of the MLMs were not affected in a significant manner

Fusion Plasma Theory project summaries

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively-participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at US government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the US Fusion Energy Program.

Fusion plasma theory project summaries

Science.gov (United States)

1993-10-01

This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at U.S. government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the U.S. Fusion Energy Program.

Fusion Plasma Theory project summaries

International Nuclear Information System (INIS)

1993-10-01

This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively-participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at US government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the US Fusion Energy Program

Conservation of proteo-lipid nuclear membrane fusion machinery during early embryogenesis.

Science.gov (United States)

Byrne, Richard D; Veeriah, Selvaraju; Applebee, Christopher J; Larijani, Banafshé

2014-01-01

The fusogenic lipid diacylglycerol is essential for remodeling gamete and zygote nuclear envelopes (NE) during early embryogenesis. It is unclear whether upstream signaling molecules are likewise conserved. Here we demonstrate PLCγ and its activator SFK1, which co-operate during male pronuclear envelope formation, also promote the subsequent male and female pronuclear fusion. PLCγ and SFK1 interact directly at the fusion site leading to PLCγ activation. This is accompanied by a spatially restricted reduction of PtdIns(4,5)P2. Consequently, pronuclear fusion is blocked by PLCγ or SFK1 inhibition. These findings identify new regulators of events in the early embryo and suggest a conserved "toolkit" of fusion machinery drives successive NE fusion events during embryogenesis.

Status report on fusion research

International Nuclear Information System (INIS)

Burkhart, Werner

2005-01-01

At the beginning of the twenty-first century mankind is faced with the serious problem of meeting the energy demands of a rapidly industrializing population around the globe. This, against the backdrop of fast diminishing fossil fuel resources (which have been the main source of energy of the last century) and the increasing realization that the use of fossil fuels has started to adversely affect our environment, has greatly intensified the quest for alternative energy sources. In this quest, fusion has the potential to play a very important role and we are today at the threshold of realizing net energy production from controlled fusion experiments. Fusion is, today, one of the most promising of all alternative energy sources because of the vast reserves of fuel, potentially lasting several thousands of years and the possibility of a relatively 'clean' form of energy, as required for use in concentrated urban industrial settings, with minimal long term environmental implications. The last decade and a half has seen unprecedented advances in controlled fusion experiments with the discovery of new regimes of operations in experiments, production of 16 MW of fusion power and operations close to and above the so-called 'break-even' conditions. A great deal of research has also been carried out in analysing various socio-economic aspects of fusion energy. This paper briefly reviews the various aspects and achievements of fusion research all over the world during this period

Introduction to plasma physics and controlled fusion

CERN Document Server

Chen, Francis F

2016-01-01

The third edition of this classic text presents a complete introduction to plasma physics and controlled fusion, written by one of the pioneering scientists in this expanding field.  It offers both a simple and intuitive discussion of the basic concepts of the subject matter and an insight into the challenging problems of current research. This outstanding text offers students a painless introduction to this important field; for teachers, a large collection of problems; and for researchers, a concise review of the fundamentals as well as original treatments of a number of topics never before explained so clearly.  In a wholly lucid manner the second edition covered charged-particle motions, plasmas as fluids, kinetic theory, and nonlinear effects.  For the third edition, two new chapters have been added to incorporate discussion of more recent advances in the field.  The new chapter 9 on Special Plasmas covers non-neutral plasmas, pure electron plasmas, solid and ultra-cold plasmas, pair-ion plasmas, d...

Cell fusion in tumor progression: the isolation of cell fusion products by physical methods

Directory of Open Access Journals (Sweden)

Vincitorio Massimo

2011-09-01

Full Text Available Abstract Background Cell fusion induced by polyethylene glycol (PEG is an efficient but poorly controlled procedure for obtaining somatic cell hybrids used in gene mapping, monoclonal antibody production, and tumour immunotherapy. Genetic selection techniques and fluorescent cell sorting are usually employed to isolate cell fusion products, but both procedures have several drawbacks. Results Here we describe a simple improvement in PEG-mediated cell fusion that was obtained by modifying the standard single-step procedure. We found that the use of two PEG undertreatments obtains a better yield of cell fusion products than the standard method, and most of these products are bi- or trinucleated polykaryocytes. Fusion rate was quantified using fluorescent cell staining microscopy. We used this improved cell fusion and cell isolation method to compare giant cells obtained in vitro and giant cells obtained in vivo from patients with Hodgkin's disease and erythroleukemia. Conclusions In the present study we show how to improve PEG-mediated cell fusion and that cell separation by velocity sedimentation offers a simple alternative for the efficient purification of cell fusion products and to investigate giant cell formation in tumor development.

Fast subcellular localization by cascaded fusion of signal-based and homology-based methods

Directory of Open Access Journals (Sweden)

Wang Wei

2011-10-01

Full Text Available Abstract Background The functions of proteins are closely related to their subcellular locations. In the post-genomics era, the amount of gene and protein data grows exponentially, which necessitates the prediction of subcellular localization by computational means. Results This paper proposes mitigating the computation burden of alignment-based approaches to subcellular localization prediction by a cascaded fusion of cleavage site prediction and profile alignment. Specifically, the informative segments of protein sequences are identified by a cleavage site predictor using the information in their N-terminal shorting signals. Then, the sequences are truncated at the cleavage site positions, and the shortened sequences are passed to PSI-BLAST for computing their profiles. Subcellular localization are subsequently predicted by a profile-to-profile alignment support-vector-machine (SVM classifier. To further reduce the training and recognition time of the classifier, the SVM classifier is replaced by a new kernel method based on the perturbational discriminant analysis (PDA. Conclusions Experimental results on a new dataset based on Swiss-Prot Release 57.5 show that the method can make use of the best property of signal- and homology-based approaches and can attain an accuracy comparable to that achieved by using full-length sequences. Analysis of profile-alignment score matrices suggest that both profile creation time and profile alignment time can be reduced without significant reduction in subcellular localization accuracy. It was found that PDA enjoys a short training time as compared to the conventional SVM. We advocate that the method will be important for biologists to conduct large-scale protein annotation or for bioinformaticians to perform preliminary investigations on new algorithms that involve pairwise alignments.

Power system small signal stability analysis and control

CERN Document Server

Mondal, Debasish; Sengupta, Aparajita

2014-01-01

Power System Small Signal Stability Analysis and Control presents a detailed analysis of the problem of severe outages due to the sustained growth of small signal oscillations in modern interconnected power systems. The ever-expanding nature of power systems and the rapid upgrade to smart grid technologies call for the implementation of robust and optimal controls. Power systems that are forced to operate close to their stability limit have resulted in the use of control devices by utility companies to improve the performance of the transmission system against commonly occurring power system

International research co-operation in the field of controlled thermonuclear fusion

International Nuclear Information System (INIS)

Conscience, J.-F.

2003-01-01

This final report for the Swiss Federal Office of Education and Science presents a review of activities carried out in 2002 within the framework of the International Experimental Thermonuclear Reactor (ITER) project that involves contributions from Canada, Japan, the Russian Federation and the European Union. Further agreements on the development of a fusion reactor with other countries, including Switzerland, the USA and China, are mentioned. The first chapter describes the current state of research on electricity production using nuclear fusion and discusses feasibility, safety, environmental, fuel supply and economic aspects. A second chapter reviews global efforts in the fusion area, including ITER and EURATOM projects and the activities running under the European Fusion Development Agreement EFDA and the JET Implementing Agreement. Finally, a third chapter deals with fusion research activities in Switzerland and the contributions made to international research by Swiss universities and institutes

Route-Based Signal Preemption Control of Emergency Vehicle

Directory of Open Access Journals (Sweden)

Haibo Mu

2018-01-01

Full Text Available This paper focuses on the signal preemption control of emergency vehicles (EV. A signal preemption control method based on route is proposed to reduce time delay of EV at intersections. According to the time at which EV is detected and the current phase of each intersection on the travelling route of EV, the calculation methods of the earliest start time and the latest start time of green light at each intersection are given. Consequently, the effective time range of green light at each intersection is determined in theory. A multiobjective programming model, whose objectives are the minimal residence time of EV at all intersections and the maximal passing numbers of general society vehicles, is presented. Finally, a simulation calculation is carried out. Calculation results indicate that, by adopting the signal preemption method based on route, the delay of EV is reduced and the number of society vehicles passing through the whole system is increased. The signal preemption control method of EV based on route can reduce the time delay of EV and improve the evacuation efficiency of the system.

Use of data fusion to optimize contaminant transport predictions

International Nuclear Information System (INIS)

Eeckhout, E. van

1997-10-01

The original data fusion workstation, as envisioned by Coleman Research Corp., was constructed under funding from DOE (EM-50) in the early 1990s. The intent was to demonstrate the viability of fusion and analysis of data from various types of sensors for waste site characterization, but primarily geophysical. This overall concept changed over time and evolved more towards hydrogeological (groundwater) data fusion after some initial geophysical fusion work focused at Coleman. This initial geophysical fusion platform was tested at Hanford and Fernald, and the later hydrogeological fusion work has been demonstrated at Pantex, Savannah River, the US Army Letterkenny Depot, a DoD Massachusetts site and a DoD California site. The hydrogeologic data fusion package has been spun off to a company named Fusion and Control Technology, Inc. This package is called the Hydrological Fusion And Control Tool (Hydro-FACT) and is being sold as a product that links with the software package, MS-VMS (MODFLOW-SURFACT Visual Modeling System), sold by HydroGeoLogic, Inc. MODFLOW is a USGS development, and is in the public domain. Since the government paid for the data fusion development at Coleman, the government and their contractors have access to the data fusion technology in this hydrogeologic package for certain computer platforms, but would probably have to hire FACT (Fusion and Control Technology, Inc.,) and/or HydroGeoLogic for some level of software and services. Further discussion in this report will concentrate on the hydrogeologic fusion module that is being sold as Hydro-FACT, which can be linked with MS-VMS

Tritium containment of controlled thermonuclear fusion reactor

International Nuclear Information System (INIS)

Tanaka, Yoshihisa; Tsukumo, Kiyohiko; Suzuki, Tatsushi

1979-01-01

It is well known that tritium is used as the fuel for nuclear fusion reactors. The neutrons produced by the nuclear fusion reaction of deuterium and tritium react with lithium in blankets, and tritium is produced. The blankets reproduce the tritium consumed in the D-T reaction. Tritium circulates through the main cooling system and the fuel supply and evacuation system, and is accumulated. Tritium is a radioactive substance emitting β-ray with 12.6 year half-life, and harmful to human bodies. It is an isotope of hydrogen, and apt to diffuse and leak. Especially at high temperature, it permeates through materials, therefore it is important to evaluate the release of tritium into environment, to treat leaked tritium to reduce its release, and to select the method of containing tritium. The permeability of tritium and its solubility in structural materials are discussed. The typical blanket-cooling systems of nuclear fusion reactors are shown, and the tungsten coating of steam generator tubes and tritium recovery system are adopted for reducing tritium leak. In case of the Tokamak type reactor of JAERI, the tritium recovery system is installed, in which the tritium gas produced in blankets is converted to tritium steam with a Pd-Pt catalytic oxidation tower, and it is dehydrated and eliminated with a molecular sieve tower, then purified and recovered. (Kako, I.)

Information Fusion of Conflicting Input Data

Directory of Open Access Journals (Sweden)

Uwe Mönks

2016-10-01

Full Text Available Sensors, and also actuators or external sources such as databases, serve as data sources in order to realise condition monitoring of industrial applications or the acquisition of characteristic parameters like production speed or reject rate. Modern facilities create such a large amount of complex data that a machine operator is unable to comprehend and process the information contained in the data. Thus, information fusion mechanisms gain increasing importance. Besides the management of large amounts of data, further challenges towards the fusion algorithms arise from epistemic uncertainties (incomplete knowledge in the input signals as well as conflicts between them. These aspects must be considered during information processing to obtain reliable results, which are in accordance with the real world. The analysis of the scientific state of the art shows that current solutions fulfil said requirements at most only partly. This article proposes the multilayered information fusion system MACRO (multilayer attribute-based conflict-reducing observation employing the μBalTLCS (fuzzified balanced two-layer conflict solving fusion algorithm to reduce the impact of conflicts on the fusion result. The performance of the contribution is shown by its evaluation in the scope of a machine condition monitoring application under laboratory conditions. Here, the MACRO system yields the best results compared to state-of-the-art fusion mechanisms. The utilised data is published and freely accessible.

Information Fusion of Conflicting Input Data.

Science.gov (United States)

Mönks, Uwe; Dörksen, Helene; Lohweg, Volker; Hübner, Michael

2016-10-29

Sensors, and also actuators or external sources such as databases, serve as data sources in order to realise condition monitoring of industrial applications or the acquisition of characteristic parameters like production speed or reject rate. Modern facilities create such a large amount of complex data that a machine operator is unable to comprehend and process the information contained in the data. Thus, information fusion mechanisms gain increasing importance. Besides the management of large amounts of data, further challenges towards the fusion algorithms arise from epistemic uncertainties (incomplete knowledge) in the input signals as well as conflicts between them. These aspects must be considered during information processing to obtain reliable results, which are in accordance with the real world. The analysis of the scientific state of the art shows that current solutions fulfil said requirements at most only partly. This article proposes the multilayered information fusion system MACRO (multilayer attribute-based conflict-reducing observation) employing the μ BalTLCS (fuzzified balanced two-layer conflict solving) fusion algorithm to reduce the impact of conflicts on the fusion result. The performance of the contribution is shown by its evaluation in the scope of a machine condition monitoring application under laboratory conditions. Here, the MACRO system yields the best results compared to state-of-the-art fusion mechanisms. The utilised data is published and freely accessible.

Signal and data processing of small targets 1992; Proceedings of the Meeting, Orlando, FL, Apr. 20-22, 1992

Science.gov (United States)

Drummond, Oliver E.

This volume on signal and data processing of small targets contains chapters devoted to signal processing, low observable detection, systems and simulations, association and filtering in tracking, multiple sensor processing and fusion, and data processing. Papers included are on multisensor predetection fusion, adaptive whitening filters for small target detection, unified framework for IR target detection and tracking, and target detection from image sequences using pixel-based decision criterion. Attention is also given to automatic acquisition and tracking of rounds and targets for electrooptic fire control, advanced surveillance testbed and background modeling, an interacting-multiple-model algorithm for tracking targets that maneuver through coordinated turns, and angular momentum and ballistic tracking. Other papers are on a data integration (fusion) tree paradigm, single-scan tracking using N IR sensors, and track monitoring with single and multiple 2D passive sensors. (No individual items are abstracted in this volume)

Developments in plasma physics and controlled fusion

International Nuclear Information System (INIS)

Thompson, W.B.

1980-01-01

Some developments in plasma physics over the past twenty years are considered from the theoretical physics standpoint under the headings; oscillations, waves and instabilities, plasma turbulence, basic kinetic theory, and developments in fusion. (UK)

International fusion research council

International Nuclear Information System (INIS)

Belozerov, A.N.

1977-01-01

A brief history of the International Fusion Research Council (IFRC) is given and the minutes of the 1976 meeting in Garching are summarized. At the Garching meeting, the IFRC evaluated the quality of papers presented at recent IAEA conferences on plasma physics and controlled thermonuclear research, and made recommendations on the organization and timing of future meetings on nuclear fusion

A Foreign Object Damage Event Detector Data Fusion System for Turbofan Engines

Science.gov (United States)

Turso, James A.; Litt, Jonathan S.

2004-01-01

A Data Fusion System designed to provide a reliable assessment of the occurrence of Foreign Object Damage (FOD) in a turbofan engine is presented. The FOD-event feature level fusion scheme combines knowledge of shifts in engine gas path performance obtained using a Kalman filter, with bearing accelerometer signal features extracted via wavelet analysis, to positively identify a FOD event. A fuzzy inference system provides basic probability assignments (bpa) based on features extracted from the gas path analysis and bearing accelerometers to a fusion algorithm based on the Dempster-Shafer-Yager Theory of Evidence. Details are provided on the wavelet transforms used to extract the foreign object strike features from the noisy data and on the Kalman filter-based gas path analysis. The system is demonstrated using a turbofan engine combined-effects model (CEM), providing both gas path and rotor dynamic structural response, and is suitable for rapid-prototyping of control and diagnostic systems. The fusion of the disparate data can provide significantly more reliable detection of a FOD event than the use of either method alone. The use of fuzzy inference techniques combined with Dempster-Shafer-Yager Theory of Evidence provides a theoretical justification for drawing conclusions based on imprecise or incomplete data.

Inertial-confinement fusion with lasers

International Nuclear Information System (INIS)

Betti, R.; Hurricane, O. A.

2016-01-01

The quest for controlled fusion energy has been ongoing for over a half century. The demonstration of ignition and energy gain from thermonuclear fuels in the laboratory has been a major goal of fusion research for decades. Thermonuclear ignition is widely considered a milestone in the development of fusion energy, as well as a major scientific achievement with important applications to national security and basic sciences. The U.S. is arguably the world leader in the inertial con fment approach to fusion and has invested in large facilities to pursue it with the objective of establishing the science related to the safety and reliability of the stockpile of nuclear weapons. Even though significant progress has been made in recent years, major challenges still remain in the quest for thermonuclear ignition via laser fusion

Non-fusion and fusion expression of beta-galactosidase from Lactobacillus bulgaricus in Lactococcus lactis.

Science.gov (United States)

Wang, Chuan; Zhang, Chao-Wu; Liu, Heng-Chuan; Yu, Qian; Pei, Xiao-Fang

2008-10-01

To construct four recombinant Lactococcus lactis strains exhibiting high beta-galactosidase activity in fusion or non-fusion ways, and to study the influence factors for their protein expression and secretion. The gene fragments encoding beta-galactosidase from two strains of Lactobacillus bulgaricus, wch9901 isolated from yogurt and 1.1480 purchased from the Chinese Academy of Sciences, were amplified and inserted into lactococcal expression vector pMG36e. For fusion expression, the open reading frame of the beta-galactosidase gene was amplified, while for non-fusion expression, the open reading frame of the beta-galactosidase gene was amplified with its native Shine-Dalgarno sequence upstream. The start codon of the beta-galactosidase gene partially overlapped with the stop codon of vector origin open reading frame. Then, the recombinant plasmids were transformed into Escherichia coli DH5 alpha and Lactococcus lactis subsp. lactis MG1363 and confirmed by determining beta-galactosidase activities. The non-fusion expression plasmids showed a significantly higher beta-galactosidase activity in transformed strains than the fusion expression plasmids. The highest enzyme activity was observed in Lactococcus lactis transformed with the non-fusion expression plasmids which were inserted into the beta-galactosidase gene from Lactobacillus bulgaricus wch9901. The beta-galactosidase activity was 2.75 times as high as that of the native counterpart. In addition, beta-galactosidase expressed by recombinant plasmids in Lactococcus lactis could be secreted into the culture medium. The highest secretion rate (27.1%) was observed when the culture medium contained 20 g/L of lactose. Different properties of the native bacteria may have some effects on the protein expression of recombinant plasmids. Non-fusion expression shows a higher enzyme activity in host bacteria. There may be a host-related weak secretion signal peptide gene within the structure gene of Lb. bulgaricus beta

Magneized target fusion: An overview of the concept

International Nuclear Information System (INIS)

Kirkpatrick, R.C.

1994-01-01

Magnetized target fusion (MTF) seeks to take advantage of the reduction of thermal conductivity through the application of a strong magneticfield and thereby ease the requirements for reaching fusion conditions in a thermonuclear (TN) fusion fuel. A potentially important benefit of the strong field in the partial trapping of energetic charged particles to enhance energy deposition by the TN fusion reaction products. The essential physics is described. MTF appears to lead to fusion targets that require orders of magnitude less power and intensity for fusion ignition than currently proposed (unmagnetized) inertial confinement fusion (ICF) targets do, making some very energetic pulsed power drivers attractive for realizing controlled fusion

Spatially resolved soft x-ray diagnostics in fusion energy research

International Nuclear Information System (INIS)

Mlynar, J.; Weinzettl, V.; Imrisek, M.; Loeffelmann, V.

2013-01-01

With construction of ITER, the fusion community has progressed into a new stage of research with increased focus on reactor technologies. Corresponding development of diagnostic systems for fusion is required, including research of novel diagnostic methods, validation of radiation hard detectors, and tests of sensors for real-time operation and control, which comprise development of tools for fast data analyses. In parallel, diagnostic systems on running fusion experiments substantially contribute to better understanding of reactor-relevant plasma physics, in particular of energy confinement, plasma stability and transport of impurities. In this respect, spatially resolved Soft X-ray (SXR) diagnostic systems present an interesting case study of development towards reactor-relevant systems. In magnetic confinement fusion research, spatial distribution of SXR radiation with spectral range typically 1 keV - 15 keV is mostly measured by a photosensitive single-row semiconductor elements in a pinhole camera shielded by a beryllium foil. The SXR intensity strongly depends on plasma density, temperature and effective charge, which carry a valuable information on the plasma core physics. Data from SXR diagnostic can be also used for the operation control, among others due to their sensitivity to heavy impurity concentration or to the position of the peak temperature. In order to reconstruct the spatial distribution of SXR plasma emission from the measured line integrated signals, several tomographic methods have been developed and validated. However, the semiconductor elements cannot survive in harsh conditions of future fusion reactors due to radiation damage, which calls for development of radiation hard SXR cameras. In this contribution, role of the SXR diagnostics will be presented in experience and future plans of the Czech tokamak COMPASS (IPP Prague) and the French tokamak TORE SUPRA (CEA Cadarache). In IPP Prague, data from SXR cameras recently contributed to

Myoelectric signal processing for control of powered limb prostheses.

Science.gov (United States)

Parker, P; Englehart, K; Hudgins, B

2006-12-01

Progress in myoelectric control technology has over the years been incremental, due in part to the alternating focus of the R&D between control methodology and device hardware. The technology has over the past 50 years or so moved from single muscle control of a single prosthesis function to muscle group activity control of multifunction prostheses. Central to these changes have been developments in the means of extracting information from the myoelectric signal. This paper gives an overview of the myoelectric signal processing challenge, a brief look at the challenge from an historical perspective, the state-of-the-art in myoelectric signal processing for prosthesis control, and an indication of where this field is heading. The paper demonstrates that considerable progress has been made in providing clients with useful and reliable myoelectric communication channels, and that exciting work and developments are on the horizon.

Simulation of traffic control signal systems

Science.gov (United States)

Connolly, P. J.; Concannon, P. A.; Ricci, R. C.

1974-01-01

In recent years there has been considerable interest in the development and testing of control strategies for networks of urban traffic signal systems by simulation. Simulation is an inexpensive and timely method for evaluating the effect of these traffic control strategies since traffic phenomena are too complex to be defined by analytical models and since a controlled experiment may be hazardous, expensive, and slow in producing meaningful results. This paper describes the application of an urban traffic corridor program, to evaluate the effectiveness of different traffic control strategies for the Massachusetts Avenue TOPICS Project.

On the economics of fusion breeders

International Nuclear Information System (INIS)

Greenspan, E.

1984-01-01

The potential for improving the economics of tandem mirror fusion breeders by assisting them with tritium produced in the control of the client light water reactors and/or by operating them with polarized plasma is assessed. Also assessed is the promise of a Starfire tokamak and a compact reversed field pinch fusion driver for fusion breeder applications. All three approaches are found to promise a significant reduction in the cost of fusion breeder produced fissile fuel, potentially making the FB-LWR system economically competitive with conventional nuclear energy systems. (orig.) [de

Controlled energy generation from nuclear fusion. 60th year atw

Energy Technology Data Exchange (ETDEWEB)

Weiss, Georg [Pintsch Bamag AG, Frankfurt am Main (Germany)

2015-02-15

Prospects increase, that with a controlled process of nuclear fusion one day an additional nuclear energy source will be commercially exploitable. In what follows, scientific principles according to the most recent research will be presented. Since approximately 30 years we are aware of the fact, that energy in form of light and heat provided by the sun and other fixed stars since over four billions years resulted from reactions of atomic nuclei. A series of such reactions became known which are considered for 'thermonuclear' processes, for example the carbon cycle by Bethe, where hydrogen is converted into helium. Most of the reflections and experiments dealt until 1938 with the reaction between nuclei of light elements. The possibility of splitting heavy nuclei was not anticipated. Its discovery by Hahn and Strassmann was a complete surprise - so to speak a rash reaction to release energy at the end of the element row. This 'way out' captured the interest of nuclear physicist for more than a decade. Only today, by starting to construct big nuclear power plants - only today, being able to assess the possibilities and limitations of this technology, the idea of energy generation through nuclear fusion steps into the foreground of nuclear research.

Transcriptomic Profiling and Functional Characterization of Fusion Genes in Recurrent Ovarian Cancer

Science.gov (United States)

2017-09-01

late lesion (Figure 1A). 152 fusions were predicted to produce an in-frame, chimeric protein—48 being acquired in late disease and 55 being...recurrence, fusions of particular interest included an acquired WNT2-CTTNBP2 in case OVCA_04, which retained a Wnt signaling peptide in the N-terminal

ICF burn-history measurments using 17-MeV fusion gamma rays

International Nuclear Information System (INIS)

Lerche, R.A.; Cable, M.D.; Dendooven, P.G.

1995-01-01

Fusion reaction rate for inertial-confinement fusion (ICF) experiments at the Nova Laser Facility is measured with 30-ps resolution using a high-speed neutron detector. We are investigating a measurement technique based on the 16.7-MeV gamma rays that are released in deuterium-tritium fusion. Our concept is to convert gamma-ray energy into a fast burst of Cerenkov light that can be recorded with a high-speed optical detector. We have detected fusion gamma rays in preliminary experiments conducted at Nova where we used a tungsten/aerogel converter to generate Cerenkov light and an optical streak camera to record the signal

Invited and contributed papers presented at the 22. EPS conference on controlled fusion and plasma physics

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-08-01

In this report one invited and fifteen contributed papers by researchers of the `Centre de Recherche en Physique des Plasmas`, Lausanne, to the 22. EPS Conference on Controlled Fusion and Plasma Physics are assembled. figs., tabs., refs.

PKC-Mediated ZYG1 Phosphorylation Induces Fusion of Myoblasts as well as of Dictyostelium Cells

Directory of Open Access Journals (Sweden)

Aiko Amagai

2012-01-01

Full Text Available We have previously demonstrated that a novel protein ZYG1 induces sexual cell fusion (zygote formation of Dictyostelium cells. In the process of cell fusion, involvements of signal transduction pathways via Ca2+ and PKC (protein kinase C have been suggested because zygote formation is greatly enhanced by PKC activators. In fact, there are several deduced sites phosphorylated by PKC in ZYG1 protein. Thereupon, we designed the present work to examine whether or not ZYG1 is actually phosphorylated by PKC and localized at the regions of cell-cell contacts where cell fusion occurs. These were ascertained, suggesting that ZYG1 might be the target protein for PKC. A humanized version of zyg1 cDNA (mzyg1 was introduced into myoblasts to know if ZYG1 is also effective in cell fusion of myoblasts. Quite interestingly, enforced expression of ZYG1 in myoblasts was found to induce markedly their cell fusion, thus strongly suggesting the existence of a common signaling pathway for cell fusion beyond the difference of species.

A Survey on Optimal Signal Processing Techniques Applied to Improve the Performance of Mechanical Sensors in Automotive Applications

Science.gov (United States)

Hernandez, Wilmar

2007-01-01

In this paper a survey on recent applications of optimal signal processing techniques to improve the performance of mechanical sensors is made. Here, a comparison between classical filters and optimal filters for automotive sensors is made, and the current state of the art of the application of robust and optimal control and signal processing techniques to the design of the intelligent (or smart) sensors that today's cars need is presented through several experimental results that show that the fusion of intelligent sensors and optimal signal processing techniques is the clear way to go. However, the switch between the traditional methods of designing automotive sensors and the new ones cannot be done overnight because there are some open research issues that have to be solved. This paper draws attention to one of the open research issues and tries to arouse researcher's interest in the fusion of intelligent sensors and optimal signal processing techniques.

Kinase fusions are frequent in Spitz tumors and spitzoid melanomas

Science.gov (United States)

Esteve-Puig, Rosaura; Botton, Thomas; Yeh, Iwei; Lipson, Doron; Otto, Geoff; Brennan, Kristina; Murali, Rajmohan; Garrido, Maria; Miller, Vincent A.; Ross, Jeffrey S; Berger, Michael F.; Sparatta, Alyssa; Palmedo, Gabriele; Cerroni, Lorenzo; Busam, Klaus J.; Kutzner, Heinz; Cronin, Maureen T; Stephens, Philip J; Bastian, Boris C.

2014-01-01

Spitzoid neoplasms are a group of melanocytic tumors with distinctive histopathologic features. They include benign tumors (Spitz nevi), malignant tumors (spitzoid melanomas), and tumors with borderline histopathologic features and uncertain clinical outcome (atypical Spitz tumors). Their genetic underpinnings are poorly understood, and alterations in common melanoma-associated oncogenes are typically absent. Here we show that spitzoid neoplasms harbor kinase fusions of ROS1 (17%), NTRK1 (16%), ALK (10%), BRAF (5%), and RET (3%) in a mutually exclusive pattern. The chimeric proteins are constitutively active, stimulate oncogenic signaling pathways, are tumorigenic, and are found in the entire biologic spectrum of spitzoid neoplasms, including 55% of Spitz nevi, 56% of atypical Spitz tumors, and 39% of spitzoid melanomas. Kinase inhibitors suppress the oncogenic signaling of the fusion proteins in vitro. In summary, kinase fusions account for the majority of oncogenic aberrations in spitzoid neoplasms, and may serve as therapeutic targets for metastatic spitzoid melanomas. PMID:24445538

An interprojection sensor fusion approach to estimate blocked projection signal in synchronized moving grid-based CBCT system

Energy Technology Data Exchange (ETDEWEB)

Zhang, Hong; Kong, Vic [Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia 30912 (United States); Ren, Lei; Giles, William; Zhang, You [Department of Radiation Oncology, Duke University, Durham, North Carolina 27710 (United States); Jin, Jian-Yue, E-mail: jjin@gru.edu [Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia 30912 and Department of Radiology, Georgia Regents University, Augusta, Georgia 30912 (United States)

2016-01-15

Purpose: A preobject grid can reduce and correct scatter in cone beam computed tomography (CBCT). However, half of the signal in each projection is blocked by the grid. A synchronized moving grid (SMOG) has been proposed to acquire two complimentary projections at each gantry position and merge them into one complete projection. That approach, however, suffers from increased scanning time and the technical difficulty of accurately merging the two projections per gantry angle. Herein, the authors present a new SMOG approach which acquires a single projection per gantry angle, with complimentary grid patterns for any two adjacent projections, and use an interprojection sensor fusion (IPSF) technique to estimate the blocked signal in each projection. The method may have the additional benefit of reduced imaging dose due to the grid blocking half of the incident radiation. Methods: The IPSF considers multiple paired observations from two adjacent gantry angles as approximations of the blocked signal and uses a weighted least square regression of these observations to finally determine the blocked signal. The method was first tested with a simulated SMOG on a head phantom. The signal to noise ratio (SNR), which represents the difference of the recovered CBCT image to the original image without the SMOG, was used to evaluate the ability of the IPSF in recovering the missing signal. The IPSF approach was then tested using a Catphan phantom on a prototype SMOG assembly installed in a bench top CBCT system. Results: In the simulated SMOG experiment, the SNRs were increased from 15.1 and 12.7 dB to 35.6 and 28.9 dB comparing with a conventional interpolation method (inpainting method) for a projection and the reconstructed 3D image, respectively, suggesting that IPSF successfully recovered most of blocked signal. In the prototype SMOG experiment, the authors have successfully reconstructed a CBCT image using the IPSF-SMOG approach. The detailed geometric features in the

An interprojection sensor fusion approach to estimate blocked projection signal in synchronized moving grid-based CBCT system

International Nuclear Information System (INIS)

Zhang, Hong; Kong, Vic; Ren, Lei; Giles, William; Zhang, You; Jin, Jian-Yue

2016-01-01

Purpose: A preobject grid can reduce and correct scatter in cone beam computed tomography (CBCT). However, half of the signal in each projection is blocked by the grid. A synchronized moving grid (SMOG) has been proposed to acquire two complimentary projections at each gantry position and merge them into one complete projection. That approach, however, suffers from increased scanning time and the technical difficulty of accurately merging the two projections per gantry angle. Herein, the authors present a new SMOG approach which acquires a single projection per gantry angle, with complimentary grid patterns for any two adjacent projections, and use an interprojection sensor fusion (IPSF) technique to estimate the blocked signal in each projection. The method may have the additional benefit of reduced imaging dose due to the grid blocking half of the incident radiation. Methods: The IPSF considers multiple paired observations from two adjacent gantry angles as approximations of the blocked signal and uses a weighted least square regression of these observations to finally determine the blocked signal. The method was first tested with a simulated SMOG on a head phantom. The signal to noise ratio (SNR), which represents the difference of the recovered CBCT image to the original image without the SMOG, was used to evaluate the ability of the IPSF in recovering the missing signal. The IPSF approach was then tested using a Catphan phantom on a prototype SMOG assembly installed in a bench top CBCT system. Results: In the simulated SMOG experiment, the SNRs were increased from 15.1 and 12.7 dB to 35.6 and 28.9 dB comparing with a conventional interpolation method (inpainting method) for a projection and the reconstructed 3D image, respectively, suggesting that IPSF successfully recovered most of blocked signal. In the prototype SMOG experiment, the authors have successfully reconstructed a CBCT image using the IPSF-SMOG approach. The detailed geometric features in the

The yeast cell fusion protein Prm1p requires covalent dimerization to promote membrane fusion.

Directory of Open Access Journals (Sweden)

Alex Engel

2010-05-01

Full Text Available Prm1p is a multipass membrane protein that promotes plasma membrane fusion during yeast mating. The mechanism by which Prm1p and other putative regulators of developmentally controlled cell-cell fusion events facilitate membrane fusion has remained largely elusive. Here, we report that Prm1p forms covalently linked homodimers. Covalent Prm1p dimer formation occurs via intermolecular disulfide bonds of two cysteines, Cys-120 and Cys-545. PRM1 mutants in which these cysteines have been substituted are fusion defective. These PRM1 mutants are normally expressed, retain homotypic interaction and can traffic to the fusion zone. Because prm1-C120S and prm1-C545S mutants can form covalent dimers when coexpressed with wild-type PRM1, an intermolecular C120-C545 disulfide linkage is inferred. Cys-120 is adjacent to a highly conserved hydrophobic domain. Mutation of a charged residue within this hydrophobic domain abrogates formation of covalent dimers, trafficking to the fusion zone, and fusion-promoting activity. The importance of intermolecular disulfide bonding informs models regarding the mechanism of Prm1-mediated cell-cell fusion.

Perceptual relearning of binocular fusion after hypoxic brain damage: four controlled single-case treatment studies.

Science.gov (United States)

Schaadt, Anna-Katharina; Schmidt, Lena; Kuhn, Caroline; Summ, Miriam; Adams, Michaela; Garbacenkaite, Ruta; Leonhardt, Eva; Reinhart, Stefan; Kerkhoff, Georg

2014-05-01

Hypoxic brain damage is characterized by widespread, diffuse-disseminated brain lesions, which may cause severe disturbances in binocular vision, leading to diplopia and loss of stereopsis, for which no evaluated treatment is currently available. The study evaluated the effects of a novel binocular vision treatment designed to improve binocular fusion and stereopsis as well as to reduce diplopia in patients with cerebral hypoxia. Four patients with severely reduced convergent fusion, stereopsis, and reading duration due to hypoxic brain damage were treated in a single-subject baseline design, with three baseline assessments before treatment to control for spontaneous recovery (pretherapy), an assessment immediately after a treatment period of 6 weeks (posttherapy), and two follow-up tests 3 and 6 months after treatment to assess stability of improvements. Patients received a novel fusion and dichoptic training using 3 different devices designed to slowly increase fusional and disparity angle. After the treatment, all 4 patients improved significantly in binocular fusion, subjective reading duration until diplopia emerged, and 2 of 4 patients improved significantly in local stereopsis. No significant changes were observed during the pretherapy baseline period and the follow-up period, thus ruling out spontaneous recovery and demonstrating long-term stability of treatment effects. This proof-of-principle study indicates a substantial treatment-induced plasticity after hypoxia in the relearning of binocular vision and offers a viable treatment option. Moreover, it provides new hope and direction for the development of effective rehabilitation strategies to treat neurovisual deficits resulting from hypoxic brain damage.

Decision Fusion System for Bolted Joint Monitoring

Directory of Open Access Journals (Sweden)

Dong Liang

2015-01-01

Full Text Available Bolted joint is widely used in mechanical and architectural structures, such as machine tools, industrial robots, transport machines, power plants, aviation stiffened plate, bridges, and steel towers. The bolt loosening induced by flight load and environment factor can cause joint failure leading to a disastrous accident. Hence, structural health monitoring is critical for the bolted joint detection. In order to realize a real-time and convenient monitoring and satisfy the requirement of advanced maintenance of the structure, this paper proposes an intelligent bolted joint failure monitoring approach using a developed decision fusion system integrated with Lamb wave propagation based actuator-sensor monitoring method. Firstly, the basic knowledge of decision fusion and classifier selection techniques is briefly introduced. Then, a developed decision fusion system is presented. Finally, three fusion algorithms, which consist of majority voting, Bayesian belief, and multiagent method, are adopted for comparison in a real-world monitoring experiment for the large aviation aluminum plate. Based on the results shown in the experiment, a big potential in real-time application is presented that the method can accurately and rapidly identify the bolt loosening by analyzing the acquired strain signal using proposed decision fusion system.

International research co-operation in the field of controlled thermonuclear fusion

International Nuclear Information System (INIS)

2004-01-01

This 26th report by the Swiss Federal Office for Education and Science presents a review of work done in Swiss institutes in 2003 as part of international research into thermonuclear fusion. A broad outline of the project and of its significance within the wider field of thermonuclear fusion research is given. This is followed by a review of the significant events in the world of fusion research, with emphasis placed on ITER and on the EURATOM fusion programme. A further chapter summarises events in Switzerland in 2003 and the report closes with a list of contacts for more information. Three annexes provide information on the current situation in fusion research, as well as scientific and technical highlights of the work performed in 2003 at the Plasma Physics Research Centre CRPP at the Federal Institute of Technology EPFL in Lausanne, Switzerland. Annex 3 reports on results obtained at the Physics Institute of the University of Basle. The annexes are for the benefit of the technically and scientifically versed reader, and brief summaries of them are given in the main body of the report

Regulation of promyogenic signal transduction by cell-cell contact and adhesion

International Nuclear Information System (INIS)

Krauss, Robert S.

2010-01-01

Skeletal myoblast differentiation involves acquisition of the muscle-specific transcriptional program and morphological changes, including fusion into multinucleated myofibers. Differentiation is regulated by extracellular signaling cues, including cell-cell contact and adhesion. Cadherin and Ig adhesion receptors have been implicated in distinct but overlapping stages of myogenesis. N-cadherin signals through the Ig receptor Cdo to activate p38 MAP kinase, while the Ig receptor neogenin signals to activate FAK; both processes promote muscle-specific gene expression and myoblast fusion. M-cadherin activates Rac1 to enhance fusion. Specific Ig receptors (Kirre and Sns) are essential for myoblast fusion in Drosophila, also signaling through Rac, and vertebrate orthologs of Kirre and Sns have partially conserved function. Mice lacking specific cytoplasmic signaling factors activated by multiple receptors (e.g., Rac1) have strong muscle phenotypes in vivo. In contrast, mice lacking individual adhesion receptors that lie upstream of these factors have modest phenotypes. Redundancy among receptors may account for this. Many of the mammalian Ig receptors and cadherins associate with each other, and multivalent interactions within these complexes may require removal of multiple components to reveal dramatic defects in vivo. Nevertheless, it is possible that the murine adhesion receptors rate-limiting in vivo have not yet been identified or fully assessed.

Regulation of promyogenic signal transduction by cell-cell contact and adhesion

Energy Technology Data Exchange (ETDEWEB)

Krauss, Robert S., E-mail: Robert.Krauss@mssm.edu [Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, NY 10029 (United States)

2010-11-01

Skeletal myoblast differentiation involves acquisition of the muscle-specific transcriptional program and morphological changes, including fusion into multinucleated myofibers. Differentiation is regulated by extracellular signaling cues, including cell-cell contact and adhesion. Cadherin and Ig adhesion receptors have been implicated in distinct but overlapping stages of myogenesis. N-cadherin signals through the Ig receptor Cdo to activate p38 MAP kinase, while the Ig receptor neogenin signals to activate FAK; both processes promote muscle-specific gene expression and myoblast fusion. M-cadherin activates Rac1 to enhance fusion. Specific Ig receptors (Kirre and Sns) are essential for myoblast fusion in Drosophila, also signaling through Rac, and vertebrate orthologs of Kirre and Sns have partially conserved function. Mice lacking specific cytoplasmic signaling factors activated by multiple receptors (e.g., Rac1) have strong muscle phenotypes in vivo. In contrast, mice lacking individual adhesion receptors that lie upstream of these factors have modest phenotypes. Redundancy among receptors may account for this. Many of the mammalian Ig receptors and cadherins associate with each other, and multivalent interactions within these complexes may require removal of multiple components to reveal dramatic defects in vivo. Nevertheless, it is possible that the murine adhesion receptors rate-limiting in vivo have not yet been identified or fully assessed.

The role of multisensor data fusion in neuromuscular control of a sagittal arm with a pair of muscles using actor-critic reinforcement learning method.

Science.gov (United States)

Golkhou, V; Parnianpour, M; Lucas, C

2004-01-01

In this study, we consider the role of multisensor data fusion in neuromuscular control using an actor-critic reinforcement learning method. The model we use is a single link system actuated by a pair of muscles that are excited with alpha and gamma signals. Various physiological sensor information such as proprioception, spindle sensors, and Golgi tendon organs have been integrated to achieve an oscillatory movement with variable amplitude and frequency, while achieving a stable movement with minimum metabolic cost and coactivation. The system is highly nonlinear in all its physical and physiological attributes. Transmission delays are included in the afferent and efferent neural paths to account for a more accurate representation of the reflex loops. This paper proposes a reinforcement learning method with an Actor-Critic architecture instead of middle and low level of central nervous system (CNS). The Actor in this structure is a two layer feedforward neural network and the Critic is a model of the cerebellum. The Critic is trained by the State-Action-Reward-State-Action (SARSA) method. The Critic will train the Actor by supervisory learning based on previous experiences. The reinforcement signal in SARSA is evaluated based on available alternatives concerning the concept of multisensor data fusion. The effectiveness and the biological plausibility of the present model are demonstrated by several simulations. The system showed excellent tracking capability when we integrated the available sensor information. Addition of a penalty for activation of muscles resulted in much lower muscle coactivation while keeping the movement stable.

Controlled thermonuclear fusion. Present state and prospective

International Nuclear Information System (INIS)

Consoli, T.

1976-01-01

The interest of thermonuclear fusion for energy production is underlined. The present state of the research in this field is presented, emphasis being given to Tokamak configurations. The problems concerning confinement and additional heating in these devices are presented [fr

The transition zone above a lumbosacral fusion.

Science.gov (United States)

Hambly, M F; Wiltse, L L; Raghavan, N; Schneiderman, G; Koenig, C

1998-08-15

The clinical and radiographic effect of a lumbar or lumbosacral fusion was studied in 42 patients who had undergone a posterolateral fusion with an average follow-up of 22.6 years. To examine the long-term effects of posterolateral lumbar or lumbosacral fusion on the cephalad two motion segments (transition zone). It is commonly held that accelerated degeneration occurs in the motion segments adjacent to a fusion. Most studies are of short-term, anecdotal, uncontrolled reports that pay particular attention only to the first motion segment immediately cephalad to the fusion. Forty-two patients who had previously undergone a posterolateral lumbar or lumbosacral fusion underwent radiographic and clinical evaluation. Rate of fusion, range of motion, osteophytes, degenerative spondylolisthesis, retrolisthesis, facet arthrosis, disc ossification, dynamic instability, and disc space height were all studied and statistically compared with an age- and gender-matched control group. The patient's self-reported clinical outcome was also recorded. Degenerative changes occurred at the second level above the fused levels with a frequency equal to those occurring in the first level. There was no statistical difference between the study group and the cohort group in the presence of radiographic changes within the transition zone. In those patients undergoing fusion for degenerative processes, 75% reported a good to excellent outcome, whereas 84% of those undergoing fusion for spondylolysis or spondylolisthesis reported a good to excellent outcome. Radiographic changes occur within the transition zone cephalad to a lumbar or lumbosacral fusion. However, these changes are also seen in control subjects who have had no surgery.

Chaos control applied to cardiac rhythms represented by ECG signals

International Nuclear Information System (INIS)

Borem Ferreira, Bianca; Amorim Savi, Marcelo; Souza de Paula, Aline

2014-01-01

The control of irregular or chaotic heartbeats is a key issue in cardiology. In this regard, chaos control techniques represent a good alternative since they suggest treatments different from those traditionally used. This paper deals with the application of the extended time-delayed feedback control method to stabilize pathological chaotic heart rhythms. Electrocardiogram (ECG) signals are employed to represent the cardiovascular behavior. A mathematical model is employed to generate ECG signals using three modified Van der Pol oscillators connected with time delay couplings. This model provides results that qualitatively capture the general behavior of the heart. Controlled ECG signals show the ability of the strategy either to control or to suppress the chaotic heart dynamics generating less-critical behaviors. (paper)

Beam dancer fusion device

International Nuclear Information System (INIS)

Maier, H.B.

1984-01-01

To accomplish fusion of two or more fusion fuel elements numerous minute spots of energy or laser light are directed to a micro target area, there to be moved or danced about by a precision mechanical controlling apparatus at the source of the laser light or electromagnetic energy beams, so that merging and coinciding patterns of light or energy beams can occur around the area of the fuel atoms or ions. The projecting of these merging patterns may be considered as target searching techniques to locate responsive clusters of fuel elements and to compress such elements into a condition in which fusion may occur. Computerized programming may be used

Papers presented at the fourteenth international conference on plasma physics and controlled nuclear fusion research

International Nuclear Information System (INIS)

1994-01-01

This report contains the contributions of the CIEMAT's Fusion Unit to the 14th International Conference on Plasma Physics and Controlled Nuclear Fusion Research that was held by the International Atomic Energy Agency in Wurzburg, Germany from 30 September to 7 October 1992. Three papers were presented that summarized the main lines of work done in the Unit during the previous two years: The first one on the theoretical advances in the understanding of the Flexible Heliac TJ-II under construction, the second on the confinement studies performed in the operating TJ-I Tokamak and the third one on the description of the physical properties of the soon to be started TJ-IU Torsatron. (Author) 25 refs

Extending the capabilities of the DIII-D Plasma Control System for worldwide fusion research collaborations

International Nuclear Information System (INIS)

Penaflor, B.G.; Ferron, J.R.; Walker, M.L.; Humphreys, D.A.; Leuer, J.A.; Piglowski, D.A.; Johnson, R.D.; Xiao, B.J.; Hahn, S.H.; Gates, D.A.

2009-01-01

This paper will discuss the recent enhancements which have been made to the DIII-D Plasma Control System (PCS) in order to further extend its usefulness as a shared tool for worldwide fusion research. The PCS developed at General Atomics is currently being used in a number of fusion research experiments worldwide, including the DIII-D Tokamak Facility in San Diego, and most recently the KSTAR Tokamak in South Korea. A number of enhancements have been made to support the ongoing needs of the DIII-D Tokamak in addition to meeting the needs of other PCS users worldwide. Details of the present PCS hardware and software architecture along with descriptions of the latest enhancements will be given.

Distributed intelligence in a LAN architecture increases the flexibility in control systems for fusion experiments

International Nuclear Information System (INIS)

Tenten, W.; Fuss, L.; Hoge, W.

1987-01-01

The control system for the TEXTOR Neutral Beam Injectors is designed implementing approved concepts and techniques. A powerful super mini computer serves as a central node between the operators console and the experimental process. Devices form a console for suitable man machine interaction. The link to the process is mainly based on communication with a network of industry standard programmable controllers. A distinction is made between the functionally dedicated and in most cases locally distributed logic controllers, a central controller and the computerized console level. Introduction of such networks in control system for fusion experiments results in a number of advantages

Temperature derivatives for fusion reactivity of D-D and D-T

Energy Technology Data Exchange (ETDEWEB)

Langenbrunner, James R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Makaruk, Hanna Ewa [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-11-29

Deuterium-tritium (D-T) and deuterium-deuterium (D-D) fusion reaction rates are observable using leakage gamma flux. A direct measurement of γ-rays with equipment that exhibits fast temporal response could be used to infer temperature, if the detector signal is amenable for taking the logarithmic time-derivative, alpha. We consider the temperature dependence for fusion cross section reactivity.

Controlled thermonuclear fusion and the latest progress on China's HT-7 superconducting tokamak

International Nuclear Information System (INIS)

Li Jiangang; Yang Yu

2003-01-01

After 50 years of research on controlled thermonuclear fusion, a new stage will be reached in 2003, when a site for the International Thermonuclear Experimental Reactor project will be chosen to start the construction. Scientists hope that this project could herald a new era in which the energy problem will be solved completely. The great progress made on the HT-7 superconducting tokamak in China has provided positive and powerful support for fusion research. The HT-7 is one of the only two superconducting tokamaks in the world that can carry out minute-scale high temperature plasma research, and has achieved a duration of 63.95s for the hot plasma discharge. This is a major step towards real steady-state operation of the tokamak configuration. We present an overview of the latest progress on the tokamak experiments in the Institute of Plasma Physics, Chinese Academy of Sciences

Research programme on controlled thermonuclear fusion - Synthesis report 2010

International Nuclear Information System (INIS)

Vaucher, C.; Tran, M. Q.; Villard, L.; Marot, L.

2011-01-01

Since 1978, research on thermonuclear fusion in Switzerland is closely related to the research programme of the European Atomic Energy Community (EURATOM). The Swiss projects tackle aspects of plasma physics and fusion technology. Switzerland participates to the construction and operation of the Joint European Torus (JET). The International Thermonuclear Experimental Reactor (ITER) is being built; the first plasma is expected in 2019. The 'Centre de Recherches en Physique des Plasmas' (CRPP) of the EPFL participates to EURATOM scientific and technological projects in magnetic confinement physics, through an experimental contribution (the Variable Configuration Tokamak, TCV) and theoretical studies. Thanks to the large flexibility of the TCV design and operation modus, plasmas of different shapes can be created and controlled, what is a very useful option to verify numerical simulation results. Besides, the injection of millimetre waves allows directing the injected power according to specific profiles. A configuration of type 'snowflakes' could be created, reducing the power deposition at the edge of the plasma. Theoretical studies on turbulence have improved the plasma stability in the TCV. For the first time in the world, TCV could reach a stable plasma, the plasma current being generated using the so-called 'bootstrap' phenomenon. Besides turbulence, studies were focused on heat and particle transport in tokamaks, on an analysis of the equilibrium and magneto-hydrodynamic stability of tokamaks and stellarators, on the application of radiofrequency waves and on the optimization of new confinement configurations. Experiments in the JET facility confirmed the numerical results of theoretical simulations. The TORPEX facility, which is simpler than TCV, allows high space-temporal resolution measurements for the study of turbulences and plasma threads ('blobs'). At the Paul Scherrer Institute (PSI), research topics include superconductivity and materials. The Fusion

The perspectives of fusion energy: The roadmap towards energy production and fusion energy in a distributed energy system

DEFF Research Database (Denmark)

Naulin, Volker; Juul Rasmussen, Jens; Korsholm, Søren Bang

2014-01-01

at very high temperature where all matter is in the plasma state as the involved energies are orders of magnitude higher than typical chemical binding energies. It is one of the great science and engineering challenges to construct a viable power plant based on fusion energy. Fusion research is a world...... The presentation will discuss the present status of the fusion energy research and review the EU Roadmap towards a fusion power plant. Further the cost of fusion energy is assessed as well as how it can be integrated in the distributed energy system......Controlled thermonuclear fusion has the potential of providing an environmentally friendly and inexhaustible energy source for mankind. Fusion energy, which powers our sun and the stars, is released when light elements, such as the hydrogen isotopes deuterium and tritium, fuse together. This occurs...

Multi-sensor information fusion method for vibration fault diagnosis of rolling bearing

Science.gov (United States)

Jiao, Jing; Yue, Jianhai; Pei, Di

2017-10-01

Bearing is a key element in high-speed electric multiple unit (EMU) and any defect of it can cause huge malfunctioning of EMU under high operation speed. This paper presents a new method for bearing fault diagnosis based on least square support vector machine (LS-SVM) in feature-level fusion and Dempster-Shafer (D-S) evidence theory in decision-level fusion which were used to solve the problems about low detection accuracy, difficulty in extracting sensitive characteristics and unstable diagnosis system of single-sensor in rolling bearing fault diagnosis. Wavelet de-nosing technique was used for removing the signal noises. LS-SVM was used to make pattern recognition of the bearing vibration signal, and then fusion process was made according to the D-S evidence theory, so as to realize recognition of bearing fault. The results indicated that the data fusion method improved the performance of the intelligent approach in rolling bearing fault detection significantly. Moreover, the results showed that this method can efficiently improve the accuracy of fault diagnosis.

Passive in-vehicle driver breath alcohol detection using advanced sensor signal acquisition and fusion.

Science.gov (United States)

Ljungblad, Jonas; Hök, Bertil; Allalou, Amin; Pettersson, Håkan

2017-05-29

The research objective of the present investigation is to demonstrate the present status of passive in-vehicle driver breath alcohol detection and highlight the necessary conditions for large-scale implementation of such a system. Completely passive detection has remained a challenge mainly because of the requirements on signal resolution combined with the constraints of vehicle integration. The work is part of the Driver Alcohol Detection System for Safety (DADSS) program aiming at massive deployment of alcohol sensing systems that could potentially save thousands of American lives annually. The work reported here builds on earlier investigations, in which it has been shown that detection of alcohol vapor in the proximity of a human subject may be traced to that subject by means of simultaneous recording of carbon dioxide (CO 2 ) at the same location. Sensors based on infrared spectroscopy were developed to detect and quantify low concentrations of alcohol and CO 2 . In the present investigation, alcohol and CO 2 were recorded at various locations in a vehicle cabin while human subjects were performing normal in-step procedures and driving preparations. A video camera directed to the driver position was recording images of the driver's upper body parts, including the face, and the images were analyzed with respect to features of significance to the breathing behavior and breath detection, such as mouth opening and head direction. Improvement of the sensor system with respect to signal resolution including algorithm and software development, and fusion of the sensor and camera signals was successfully implemented and tested before starting the human study. In addition, experimental tests and simulations were performed with the purpose of connecting human subject data with repeatable experimental conditions. The results include occurrence statistics of detected breaths by signal peaks of CO 2 and alcohol. From the statistical data, the accuracy of breath alcohol

Mass Producing Targets for Nuclear Fusion

Science.gov (United States)

Wang, T. G.; Elleman, D. D.; Kendall, J. M.

1983-01-01

Metal-encapsulating technique advances prospects of controlling nuclear fusion. Prefilled fusion targets form at nozzle as molten metal such as tin flows through outer channel and pressurized deuterium/tritium gas flows through inner channel. Molten metal completely encloses gas charge as it drops off nozzle.

Fusion environment sensitive flow and fracture processes

International Nuclear Information System (INIS)

1980-01-01

As a planning activity, the objectives of the workshop were to list, prioritize and milestone the activities necessary to understand, interpret and control the mechanical behavior of candidate fusion reactor alloys. Emphasis was placed on flow and fracture processes which are unique to the fusion environment since the national fusion materials program must evaluate these effects without assistance from other reactor programs

Intrafocal heterogeneity of ERG protein expression and gene fusion pattern in prostate cancer.

Science.gov (United States)

Suh, Ja Hee; Park, Jeong Hwan; Lee, Cheol; Moon, Kyung Chul

2017-10-01

Prostate cancer is considered to be highly heterogeneous, with various morphologic features and biologic behaviors. The TMPRSS2-ERG gene fusion is the most frequently observed genetic aberration in prostate cancer. The aim of this study was to elucidate the intrafocal heterogeneity of ERG gene fusion status. ERG immunohistochemistry (IHC) was performed in samples from 168 prostate cancer patients who had undergone radical prostatectomy, and 40 cases showing ERG-positive IHC staining were selected for tissue microarray (TMA) construction. Two to six representative cores were selected from each tumor focus. In the cases with heterogeneous ERG IHC staining intensity, the areas showing different intensities were separately selected. Using the TMA blocks, IHC and fluorescence in situ hybridization (FISH) were conducted to evaluate the heterogeneity of ERG protein expression and ERG fusion gene patterns, respectively, in a single tumor focus. Heterogeneity of ERG IHC staining was defined as the simultaneous presence of negative and positive cores in the same tumor focus. Heterogeneity of ERG FISH was defined by the presence of cores with positive and negative FISH signals or cores with break-apart and interstitial deletion FISH signals in the same tumor focus. A total of 202 TMA cores were isolated from 40 ERG-positive cases. Of the 202 total cores, 19 were negative for ERG IHC staining, and 46 showed 1+, 52 showed 2+, and 85 showed 3+ ERG staining intensity. Eleven cores were negative for ERG FISH signal, 119 cores showed ERG break-apart FISH signals, and the remaining 72 cores revealed interstitial deletion. Intrafocal heterogeneity of ERG IHC staining was found in 20% (8/40) of cases, and intrafocal heterogeneity of ERG gene fusion pattern was found in 32.5% (13/40) of cases. In summary, this study showed significantly frequent intrafocal heterogeneity of ERG protein expression, gene fusion status and fusion pattern. This heterogeneity can be caused by the development

The role of improved fusion concepts

International Nuclear Information System (INIS)

Nelson, D.B.; Linford, R.K.; Liu, C.S.; Logan, B.G.; Rose, P.H.

1985-01-01

The U.S. Dept. of Energy discusses concept improvement in the tokamak and concept improvement in the mirror. Controlled Thermonuclear Research comments on what constitutes an attractive fusion reactor, and provides a table of achieved parameters of RFP, FRC and the spheromak experiments. GA Technologies Inc. remarks on the direction which industry must take in the fusion program. The Lawrence Livermore National Laboratory concentrates on commercial reactor studies. Spectra Technology focuses on problems dealing with fusion proponents making a convincing and clear economic argument for fusion based on a mils per kilowat basis, and the large costs of flagship experiments. The Oak Ridge National Laboratory remarks on the need for an economic energy source for fusion. A table of cost of electricity contours is shown

The role of improved fusion concepts

Energy Technology Data Exchange (ETDEWEB)

Nelson, D.B.; Linford, R.K.; Liu, C.S.; Logan, B.G.; Rose, P.H.

1985-06-01

The U.S. Dept. of Energy discusses concept improvement in the tokamak and concept improvement in the mirror. Controlled Thermonuclear Research comments on what constitutes an attractive fusion reactor, and provides a table of achieved parameters of RFP, FRC and the spheromak experiments. GA Technologies Inc. remarks on the direction which industry must take in the fusion program. The Lawrence Livermore National Laboratory concentrates on commercial reactor studies. Spectra Technology focuses on problems dealing with fusion proponents making a convincing and clear economic argument for fusion based on a mils per kilowat basis, and the large costs of flagship experiments. The Oak Ridge National Laboratory remarks on the need for an economic energy source for fusion. A table of cost of electricity contours is shown.

Robust control of dielectric elastomer diaphragm actuator for human pulse signal tracking

Science.gov (United States)

Ye, Zhihang; Chen, Zheng; Asmatulu, Ramazan; Chan, Hoyin

2017-08-01

Human pulse signal tracking is an emerging technology that is needed in traditional Chinese medicine. However, soft actuation with multi-frequency tracking capability is needed for tracking human pulse signal. Dielectric elastomer (DE) is one type of soft actuating that has great potential in human pulse signal tracking. In this paper, a DE diaphragm actuator was designed and fabricated to track human pulse pressure signal. A physics-based and control-oriented model has been developed to capture the dynamic behavior of DE diaphragm actuator. Using the physical model, an H-infinity robust control was designed for the actuator to reject high-frequency sensing noises and disturbances. The robust control was then implemented in real-time to track a multi-frequency signal, which verified the tracking capability and robustness of the control system. In the human pulse signal tracking test, a human pulse signal was measured at the City University of Hong Kong and then was tracked using DE actuator at Wichita State University in the US. Experimental results have verified that the DE actuator with its robust control is capable of tracking human pulse signal.

Improving Vehicle Ride and Handling Using LQG CNF Fusion Control Strategy for an Active Antiroll Bar System

Directory of Open Access Journals (Sweden)

N. Zulkarnain

2014-01-01

Full Text Available This paper analyses a comparison of performance for an active antiroll bar (ARB system using two types of control strategy. First of all, the LQG control strategy is investigated and then a novel LQG CNF fusion control method is developed to improve the performances on vehicle ride and handling for an active antiroll bar system. However, the ARB system has to balance the trade-off between ride and handling performance, where the CNF consists of a linear feedback law and a nonlinear feedback law. Typically, the linear feedback is designed to yield a quick response at the initial stage, while the nonlinear feedback law is used to smooth out overshoots in the system output when it approaches the target reference. The half car model is combined with a linear single track model with roll dynamics which are used for the analysis and simulation of ride and handling. The performances of the control strategies are compared and the simulation results show the LQG CNF fusion improves the performances in vehicle ride and handling.

Overview of fusion reactor safety

International Nuclear Information System (INIS)

Cohen, S.; Crocker, J.G.

1981-01-01

Use of deuterium-tritium burning fusion reactors requires examination of several major safety and environmental issues: (1) tritium inventory control, (2) neutron activation of structural materials, fluid streams and reactor hall environment, (3) release of radioactivity from energy sources including lithium spill reactions, superconducting magnet stored energy release, and plasma disruptions, (4) high magnetic and electromagnetic fields associated with fusion reactor superconducting magnets and radio frequency heating devices, and (5) handling and disposal of radioactive waste. Early recognition of potential safety problems with fusion reactors provides the opportunity for improvement in design and materials to eliminate or greatly reduce these problems. With an early start in this endeavor, fusion should be among the lower risk technologies for generation of commercial electrical power

Thermonuclear fusion power

Energy Technology Data Exchange (ETDEWEB)

Lehnert, B

1977-01-01

The present state and future possibilities of controlled-nuclear-fusion research are reviewed, including basic concepts and problems, as well as various approaches based on magnetic- and nonmagnetic-confinement schemes. Considerable progress has so far been made in both plasma physics and fusion-reactor technology, and a closer relationship has been established between theory and experiments. Still, none of the present approaches will, for certain, lead to the final solution of a full-scale reactor. Intensified work along broad lines, with emphasis also on basic research and new ideas, is necessary for future success.

Fusion of footsteps and face biometrics on an unsupervised and uncontrolled environment

Science.gov (United States)

Vera-Rodriguez, Ruben; Tome, Pedro; Fierrez, Julian; Ortega-Garcia, Javier

2012-06-01

This paper reports for the first time experiments on the fusion of footsteps and face on an unsupervised and not controlled environment for person authentication. Footstep recognition is a relatively new biometric based on signals extracted from people walking over floor sensors. The idea of the fusion between footsteps and face starts from the premise that in an area where footstep sensors are installed it is very simple to place a camera to capture also the face of the person that walks over the sensors. This setup may find application in scenarios like ambient assisted living, smart homes, eldercare, or security access. The paper reports a comparative assessment of both biometrics using the same database and experimental protocols. In the experimental work we consider two different applications: smart homes (small group of users with a large set of training data) and security access (larger group of users with a small set of training data) obtaining results of 0.9% and 5.8% EER respectively for the fusion of both modalities. This is a significant performance improvement compared with the results obtained by the individual systems.

Design concept of control system for cryogenic distillation columns of fusion reactor

International Nuclear Information System (INIS)

Yamanishi, Toshihiko; Okuno, Kenji

1993-09-01

Control systems were designed for cryogenic distillation columns in the main fuel cycle and the breeder blanket interface systems of fusion reactors. Three basic control modes were proposed for the column whose top product was more important; the column whose bottom product is more important; and the column having a feed back stream. The key component in the important product stream was selected for each column, and the analysis method for measurement of this key component was discussed. Some of the columns need the gas chromatography as the analysis instrument of the control system. The time required for the measurement of product purity by the gas chromatography considerably affects the stability of the control system. A significant conclusion is that permissible time is about 20 min. It is possible to complete the measurement within 20 minute by the gas chromatography. The gas chromatography is applicable for the control system of the column. (author)

Argonne National Laboratory papers presented at third ANS topical meeting on the technology of controlled nuclear fusion

International Nuclear Information System (INIS)

1978-01-01

The 9 papers included in this Technical Memorandum were presented at the Third ANS Topical Meeting on the Technology of Controlled Nuclear Fusion that was held in Santa Fe, New Mexico on May 9-11, 1978

Fusion energy research for ITER and beyond

International Nuclear Information System (INIS)

Romanelli, Francesco; Laxaaback, Martin

2011-01-01

The achievement in the last two decades of controlled fusion in the laboratory environment is opening the way to the realization of fusion as a source of sustainable, safe and environmentally responsible energy. The next step towards this goal is the construction of the International Thermonuclear Experimental Reactor (ITER), which aims to demonstrate net fusion energy production on the reactor scale. This paper reviews the current status of magnetic confinement fusion research in view of the ITER project and provides an overview of the main remaining challenges on the way towards the realization of commercial fusion energy production in the second half of this century. (orig.)

Ceramics for fusion devices

International Nuclear Information System (INIS)

Clinard, F.W. Jr.

1984-01-01

Ceramics are required for a number of applications in fusion devices, among the most critical of which are magnetic coil insulators, windows for RF heating systems, and structural uses. Radiation effects dominate consideration of candidate materials, although good pre-irradiation properties are a requisite. Materials and components can be optimized by careful control of chemical and microstructural content, and application of brittle material design and testing techniques. Future directions for research and development should include further extension of the data base in the areas of electrical, structural, and thermal properties; establishment of a fission neutron/fusion neutron correlation including transmutation gas effects; and development of new materials tailored to meet the specific needs of fusion reactors

Digital Signal Processing and Control for the Study of Gene Networks

Science.gov (United States)

Shin, Yong-Jun

2016-04-01

Thanks to the digital revolution, digital signal processing and control has been widely used in many areas of science and engineering today. It provides practical and powerful tools to model, simulate, analyze, design, measure, and control complex and dynamic systems such as robots and aircrafts. Gene networks are also complex dynamic systems which can be studied via digital signal processing and control. Unlike conventional computational methods, this approach is capable of not only modeling but also controlling gene networks since the experimental environment is mostly digital today. The overall aim of this article is to introduce digital signal processing and control as a useful tool for the study of gene networks.

A neutron poison tritium breeding controller applied to a water cooled fusion reactor model

International Nuclear Information System (INIS)

Morgan, L.W.G.; Packer, L.W.

2014-01-01

Highlights: • The issue of a potentially producing a large tritium surplus inventory, within a solid breeder, is addressed. • A possible solution to this problem is presented in the form of a neutron poison based tritium production controller. • The tritium surplus inventory has been modelled by the FATI code for a simplified WCCB model and as a function of time. • It has been demonstrated that the tritium surplus inventory can be managed, which may impact on safety considerations. - Abstract: The generation of tritium in sufficient quantities is an absolute requirement for a next step fusion device such as DEMO due to the scarcity of tritium sources. Although the production of sufficient quantities of tritium will be one of the main challenges for DEMO, within an energy economy featuring several fusion power plants the active control of tritium production may be required in order to manage surplus tritium inventories at power plant sites. The primary reason for controlling the tritium inventory in such an economy would therefore be to minimise the risk and storage costs associated with large quantities of surplus tritium. In order to ensure that enough tritium will be produced in a reactor which contains a solid tritium breeder, over the reactor's lifetime, the tritium breeding rate at the beginning of its lifetime is relatively high and reduces over time. This causes a large surplus tritium inventory to build up until approximately halfway through the lifetime of the blanket, when the inventory begins to decrease. This surplus tritium inventory could exceed several tens of kilograms of tritium, impacting on possible safety and licensing conditions that may exist. This paper describes a possible solution to the surplus tritium inventory problem that involves neutron poison injection into the coolant, which is managed with a tritium breeding controller. A simple PID controller and is used to manage the injection of the neutron absorbing compounds into

A neutron poison tritium breeding controller applied to a water cooled fusion reactor model

Energy Technology Data Exchange (ETDEWEB)

Morgan, L.W.G., E-mail: Lee.Morgan@CCFE.ac.uk; Packer, L.W.

2014-10-15

Highlights: • The issue of a potentially producing a large tritium surplus inventory, within a solid breeder, is addressed. • A possible solution to this problem is presented in the form of a neutron poison based tritium production controller. • The tritium surplus inventory has been modelled by the FATI code for a simplified WCCB model and as a function of time. • It has been demonstrated that the tritium surplus inventory can be managed, which may impact on safety considerations. - Abstract: The generation of tritium in sufficient quantities is an absolute requirement for a next step fusion device such as DEMO due to the scarcity of tritium sources. Although the production of sufficient quantities of tritium will be one of the main challenges for DEMO, within an energy economy featuring several fusion power plants the active control of tritium production may be required in order to manage surplus tritium inventories at power plant sites. The primary reason for controlling the tritium inventory in such an economy would therefore be to minimise the risk and storage costs associated with large quantities of surplus tritium. In order to ensure that enough tritium will be produced in a reactor which contains a solid tritium breeder, over the reactor's lifetime, the tritium breeding rate at the beginning of its lifetime is relatively high and reduces over time. This causes a large surplus tritium inventory to build up until approximately halfway through the lifetime of the blanket, when the inventory begins to decrease. This surplus tritium inventory could exceed several tens of kilograms of tritium, impacting on possible safety and licensing conditions that may exist. This paper describes a possible solution to the surplus tritium inventory problem that involves neutron poison injection into the coolant, which is managed with a tritium breeding controller. A simple PID controller and is used to manage the injection of the neutron absorbing compounds into

30 CFR 77.515 - Bare signal or control wires; voltage.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bare signal or control wires; voltage. 77.515 Section 77.515 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE... COAL MINES Electrical Equipment-General § 77.515 Bare signal or control wires; voltage. The voltage on...

Fusion of hard and soft control strategies for the robotic hand

CERN Document Server

Chen, Cheng-Hung

2018-01-01

Long considered the stuff of science fiction, a prosthetic hand capable of fully replicating all of that appendage's various functions is closer to becoming reality than ever before. This book provides a comprehensive report on exciting recent developments in hybrid control techniques—one of the most crucial hurdles to be overcome in creating smart prosthetic hands. Coauthored by two of the world's foremost pioneering experts in the field, Fusion of Hard and Soft Control Strategies for the Robotic Hand treats robotic hands for multiple applications. It begins with an overview of advances in main control techniques that have been made over the past decade before addressing the military context for affordable robotic hand technology with tactile and/or proprioceptive feedback for hand amputees. Kinematics, homogene us transformations, inverse and differential kinematics, trajectory planning, and dynamic models of two-link thumb and three-link index finger are discussed in detail. The remainder of the book is...

Control of ITBs in Fusion Self-Heated Plasmas

Science.gov (United States)

Panta, Soma; Newman, David; Terry, Paul; Sanchez, Raul

2015-11-01

Simple dynamical models have been able to capture a remarkable amount of the dynamics of the transport barriers found in many devices, including the often disconnected nature of the electron thermal transport channel sometimes observed in the presence of a standard (``ion channel'') barrier. By including in this rich though simple dynamic transport model an evolution equation for electron fluctuations we have previously investigated the interaction between the formation of the standard ion channel barrier and the somewhat less common electron channel barrier. The electron channel formation and evolution is even more sensitive to the alignment of the various gradients making up the sheared radial electric field then the ion barrier is. Because of this sensitivity and coupling of the barrier dynamics, the dynamic evolution of the fusion self-heating profile can have a significant impact on the barrier location and dynamics. To investigate this, self-heating has been added this model and the impact of the self-heating on the formation and controllability of the various barriers is explored. It has been found that the evolution of the heating profiles can suppress or collapse the electron channel barrier. NBI and RF schemes will be investigated for profile/barrier control.

Signal validation and failure correction algorithms for PWR steam generator feedwater control

International Nuclear Information System (INIS)

Nasrallah, C.N.; Graham, K.F.

1986-01-01

A critical contributor to the reliability of a nuclear power plant is the reliability of the control systems which maintain plant operating parameters within desired limits. The most difficult system to control in a PWR nuclear power plant and the one which causes the most reactor trips is the control of the feedwater flow to the steam generators. The level in the steam generator must be held within relatively narrow limits, with reactor trips set for both too high and too low a level. The steam generator level is inherently unstable in that it is an open integrator of feedwater flow steam flow mismatch. The steam generator feedwater control system relies on sensed variables in order to generate the appropriate feedwater valve control signal. In current systems, each of these sensed variables comes from a single sensor which may be a separate control sensor or one of the redundant protection sensors that is manually selected by the operator. In case this single signal is false, either due to sensor malfunction or due to a test signal being substituted during periodic test and maintenance, the control system will generate a wrong control signal to the feedwater control valve. This will initiate a steam generator level upset. The solution to this problem is for the control system to sense a given variable with more than one redundant sensor. Normally there are three or four sensors for each variable monitored by the reactor protection system. The techniques discussed allow the control system to compare these redundant sensor signals and generate a validated signal for each measured variable that is insensitive to false signals

The history of controlled fusion research

International Nuclear Information System (INIS)

Trocheris, M.

1980-01-01

The idea of using nuclear reaction between light elements to produce energy for peaceful objectives originated towards the mid-forties. In this work, the author traces the various stages of reserach undertaken in this field from the first fusion experiments to the projects now in course of production. Research scientists have travelled a long, hard road to reach a new development phase during which technological problems will play a prominent part [fr

The ORNL Controlled Fusion Atomic Data Center: Overview of Activities 2011

International Nuclear Information System (INIS)

Schultz, D.R.

2011-01-01

The Controlled Fusion Atomic Data Center (CFADC) of the Oak Ridge National Laboratory continued operation aimed at collecting, evaluating, and disseminating atomic, molecular, and particle-surface interaction (AM and PSI) data needed by both the U.S. and international plasma science communities. This work has been carried out within an overarching atomic physics research group which produces much of the required data through an active experimental and theoretical science program. The production of an annotated bibliography of AM and PSI literature relevant to plasma science continues to be among the most important activities of the data center, forming the basis for the CFADC on-line bibliographic search engine and a significant part of the IAEA A+M Data Unit's 'International Bulletin on Atomic and Molecular Data for Fusion.' Also chief among the data center's activities are responses to specific data requests from the plasma science community, leading to either rapid feedback using existing data resources or long term data production projects, as well as participation in IAEA Coordinated Research Programs including recently 'Data for Surface Composition Dynamics Relevant to Erosion Processes' and 'Atomic and Molecular Data for Plasma Modeling.' Highlights of recent data production projects include the following: Experimental and theoretical data for inelastic electron-hydrocarbon reactions, large scale computational results for particle reflection from surfaces, measurements of chemical sputtering from carbon, inaugural experiments considering molecular ion collisions with neutral hydrogen, and expansion of the database of elastic and related transport cross sections calculated for intrinsic and extrinsic impurities in hydrogen plasmas. Progress is being hampered owing to news from the US Department of Energy that it plans to close out the program after a ramp down of funding in 2012, following a distinguished 52 year history of contributions to the US and

Fusion research in Hungary

International Nuclear Information System (INIS)

Zoletnik, S.

2004-01-01

Hungarian fusion research started in the 1970s, when the idea of installing a small tokamak experiment emerged. In return to computer equipment a soviet tokamak was indeed sent to Hungary and started to operate as MT-1 at the Central Research Institute for Physics (KFKI) in 1979. Major research topics included diagnostic development, edge plasma studies and investigation of disruptions. Following a major upgrade in 1992 (new vacuum vessel, active position control and PC network based data acquisition system) the MT-1M tokamak was used for the study of transport processes with trace impurity injection, micropellet ablation studies, X-ray tomography and laser blow-off diagnostic development. Although funding ceased in the middle of the 90's the group was held alive by collaborations with EU fusion labs: FZ -Juelich, IPP-Garching and CRPP-EPFL Lausanne. In 1998 the machine was dismantled due to reorganization of the Hungarian Academy of Sciences. New horizons opened to fusion research from 1999, when Hungary joined EURATOM and a fusion Association was formed. Since then fusion physics studies are done in collaboration with major EU fusion laboratories, Hungarian researchers also play an active role in JET diagnostics upgrade and ITER design. Major topics are pellet ablation studies, plasma turbulence diagnosis using Beam Emission Spectroscopy and other techniques, tomography and plasma diagnostics using various neutral beams. In fusion relevant technology R and D Hungary has less records. Before joining EURATOM some materials irradiation studies were done at the Budapest Research Reactor at KFKI-AEKI. The present day fusion technology programme focuses still on irradiation studies, nuclear material database and electromagnetic testing techniques. Increasing the fusion technology research activities is a difficult task, as the competition in Hungarian industry is very strong and the interest of organizations in long-term investments into R and D is rather weak and

Vesicular PtdIns(3,4,5)P3 and Rab7 are key effectors of sea urchin zygote nuclear membrane fusion.

Science.gov (United States)

Lete, Marta G; Byrne, Richard D; Alonso, Alicia; Poccia, Dominic; Larijani, Banafshé

2017-01-15

Regulation of nuclear envelope dynamics is an important example of the universal phenomena of membrane fusion. The signalling molecules involved in nuclear membrane fusion might also be conserved during the formation of both pronuclear and zygote nuclear envelopes in the fertilised egg. Here, we determine that class-I phosphoinositide 3-kinases (PI3Ks) are needed for in vitro nuclear envelope formation. We show that, in vivo, PtdIns(3,4,5)P 3 is transiently located in vesicles around the male pronucleus at the time of nuclear envelope formation, and around male and female pronuclei before membrane fusion. We illustrate that class-I PI3K activity is also necessary for fusion of the female and male pronuclear membranes. We demonstrate, using coincidence amplified Förster resonance energy transfer (FRET) monitored using fluorescence lifetime imaging microscopy (FLIM), a protein-lipid interaction of Rab7 GTPase and PtdIns(3,4,5)P 3 that occurs during pronuclear membrane fusion to create the zygote nuclear envelope. We present a working model, which includes several molecular steps in the pathways controlling fusion of nuclear envelope membranes. © 2017. Published by The Company of Biologists Ltd.

International fusion research

International Nuclear Information System (INIS)

Pease, R.S.

1983-01-01

Nuclear energy of the light elements deuterium and lithium can be released if the 100 MK degree temperature required for deuterium-tritium thermonuclear fusion reactions can be achieved together with sufficient thermal insulation for a net energy yield. Progress of world-wide research shows good prospect for these physical conditions being achieved by the use of magnetic field confinement and of rapidly developing heating methods. Tokamak systems, alternative magnetic systems and inertial confinement progress are described. International co-operation features a number of bilateral agreements between countries: the Euratom collaboration which includes the Joint European Torus, a joint undertaking of eleven Western European nations of Euratom, established to build and operate a major confinement experiment; the development of co-operative projects within the OECD/IEA framework; the INTOR workshop, a world-wide study under IAEA auspices of the next major step in fusion research which might be built co-operatively; and assessments of the potential of nuclear fusion by the IAEA and the International Fusion Research Council. The INTOR (International Tokamak Reactor) studies have outlined a major plant of the tokamak type to study the engineering and technology of fusion reactor systems, which might be constructed on a world-wide basis to tackle and share the investment risks of the developments which lie ahead. This paper summarizes the recent progress of research on controlled nuclear fusion, featuring those areas where international co-operation has played an important part, and describes the various arrangements by which this international co-operation is facilitated. (author)

Design of a fusion reaction-history measurement system with high temporal resolution

International Nuclear Information System (INIS)

Peng Xiaoshi; Wang Feng; Liu Shenye; Jiang Xiaohua; Tang Qi

2010-01-01

In order to accurately measure the history of fusion reaction for experimental study of inertial confinement fusion, we advance the design of a fusion reaction-history measurement system with high temporal resolution. The diagnostic system is composed of plastic scintillator and nose cone, an optical imaging system and the system of optic streak camera. Analyzing the capability of the system indicated that the instrument measured fusion reaction history at temporal resolution as low as 55ps and 40ps correspond to 2.45MeV DD neutrons and 14.03MeV DT neutrons. The instrument is able to measure the fusion reaction history at yields 1.5 x 10 9 DD neutrons, about 4 x 10 8 DT neutrons are required for a similar quality signal. (authors)

Fusion Simulation Program

International Nuclear Information System (INIS)

Greenwald, Martin

2011-01-01

Many others in the fusion energy and advanced scientific computing communities participated in the development of this plan. The core planning team is grateful for their important contributions. This summary is meant as a quick overview the Fusion Simulation Program's (FSP's) purpose and intentions. There are several additional documents referenced within this one and all are supplemental or flow down from this Program Plan. The overall science goal of the DOE Office of Fusion Energy Sciences (FES) Fusion Simulation Program (FSP) is to develop predictive simulation capability for magnetically confined fusion plasmas at an unprecedented level of integration and fidelity. This will directly support and enable effective U.S. participation in International Thermonuclear Experimental Reactor (ITER) research and the overall mission of delivering practical fusion energy. The FSP will address a rich set of scientific issues together with experimental programs, producing validated integrated physics results. This is very well aligned with the mission of the ITER Organization to coordinate with its members the integrated modeling and control of fusion plasmas, including benchmarking and validation activities. (1). Initial FSP research will focus on two critical Integrated Science Application (ISA) areas: ISA1, the plasma edge; and ISA2, whole device modeling (WDM) including disruption avoidance. The first of these problems involves the narrow plasma boundary layer and its complex interactions with the plasma core and the surrounding material wall. The second requires development of a computationally tractable, but comprehensive model that describes all equilibrium and dynamic processes at a sufficient level of detail to provide useful prediction of the temporal evolution of fusion plasma experiments. The initial driver for the whole device model will be prediction and avoidance of discharge-terminating disruptions, especially at high performance, which are a critical

Induction accelerator development for heavy ion fusion

International Nuclear Information System (INIS)

Reginato, L.L.

1993-05-01

For approximately a decade, the Heavy Ion Fusion Accelerator Research (HIFAR) group at LBL has been exploring the use of induction accelerators with multiple beams as the driver for inertial fusion targets. Scaled experiments have investigated the transport of space charge dominated beams (SBTE), and the current amplification and transverse emittance control in induction linacs (MBE-4) with very encouraging results. In order to study many of the beam manipulations required by a driver and to further develop economically competitive technology, a proposal has been made in partnership with LLNL to build a 10 MeV accelerator and to conduct a series of experiments collectively called the Induction Linac System Experiments (ILSE). The major components critical to the ILSE accelerator are currently under development. We have constructed a full scale induction module and we have tested a number of amorphous magnetic materials developed by Allied Signal to establish an overall optimal design. The electric and magnetic quadrupoles critical to the transport and focusing of heavy ion beams are also under development The hardware is intended to be economically competitive for a driver without sacrificing any of the physics or performance requirements. This paper will concentrate on the recent developments and tests of the major components required by the ILSE accelerator

Induction accelerator development for heavy ion fusion

International Nuclear Information System (INIS)

Reginato, L.L.

1993-05-01

For approximately a decade, the Heavy Ion Fusion Accelerator Research (HIFAR) group at LBL has been exploring the use of induction accelerators with multiple beams as the driver for inertial fusion targets. Scaled experiments have investigated the transport of space charge dominated beams (SBTE), and the current amplification and transverse emittance control in induction linacs (MBE-4) with very encouraging results. In order to study many of the beam manipulations required by a driver and to further develop economically competitive technology, a proposal has been made in partnership with LLNL to build a 10 MeV accelerator and to conduct a series of experiments collectively called the Induction Linac System Experiments (ILSE).The major components critical to the ILSE accelerator are currently under development. We have constructed a full scale induction module and we have tested a number of amorphous magnetic materials developed by Allied Signal to establish an overall optimal design. The electric and magnetic quadrupoles critical to the transport and focusing of heavy ion beams are also under development. The hardware is intended to be economically competitive for a driver without sacrificing any of the physics or performance requirements. This paper will concentrate on the recent developments and tests of the major components required by the ILSE accelerator

Mode-selective symmetry control for indirect-drive inertial confinement fusion hohlraums

International Nuclear Information System (INIS)

Vesey, R. A.; Slutz, S. A.; Herrmann, M. C.; Mehlhorn, T. A.; Campbell, R. B.

2008-01-01

Achieving a high degree of radiation symmetry is a critical feature of target designs for indirect-drive inertial confinement fusion. Typically, the radiation flux incident on the capsule is required to be uniform to 1% or better. It is generally possible to design a hohlraum that provides low values of higher-order asymmetry (Legendre mode P 10 and above) due to geometric averaging effects. Because low-order intrinsic asymmetry (e.g., Legendre modes P 2 and P 4 ) are less strongly reduced by geometric averaging alone, the development of innovative control techniques has been an active area of research in the inertial fusion community over the years. Shields placed inside the hohlraum are one example of a technique that has often been proposed and incorporated into hohlraum target designs. Simple mathematical considerations are presented indicating that radiation shields may be designed to specifically tune lower-order modes (e.g., P 4 ) without deleterious effects on the higher order modes. Two-dimensional view factor and radiation-hydrodynamics simulations confirm these results and support such a path to achieving a highly symmetric x-ray flux. The term ''mode-selective'' is used because these shields, essentially ring structures offset from the capsule, are designed to affect only a specific Legendre mode (or multiple modes) of interest

Robust Bio-Signal Based Control of an Intelligent Wheelchair

Directory of Open Access Journals (Sweden)

Dongyi Chen

2013-09-01

Full Text Available In this paper, an adaptive human-machine interaction (HMI method that is based on surface electromyography (sEMG signals is proposed for the hands-free control of an intelligent wheelchair. sEMG signals generated by the facial movements are obtained by a convenient dry electrodes sensing device. After the signals features are extracted from the autoregressive model, control data samples are updated and trained by an incremental online learning algorithm in real-time. Experimental results show that the proposed method can significantly improve the classification accuracy and training speed. Moreover, this method can effectively reduce the influence of muscle fatigue during a long time operation of sEMG-based HMI.

Control of earphone produced binaural signals

DEFF Research Database (Denmark)

Hammershøi, Dorte; Hoffmann, Pablo F.

2011-01-01

While most people keep a high attention to the significance of the binaural recording method, whether it is e.g. individual or non-individual (as e.g. artificial head recording), many pay less attention to the type of earphone used to reproduce the binaural signals, and to the accurate control...

Light signals for road traffic control.

NARCIS (Netherlands)

Schreuder, D.A.

1981-01-01

Signals for road traffic control are a major constituent of the modern traffic scene, particularly in built-up areas. A vast amount of research has been executed in the last two decennia, resulting in a fairly generally accepted view on what the requirements for effective traffic lights are. For the

Human Factors and Data Fusion as Part of Control Systems Resilience

Energy Technology Data Exchange (ETDEWEB)

David I. Gertman

2009-05-01

Human performance and human decision making is counted upon as a crucial aspect of overall system resilience. Advanced control systems have the potential to provide operators and asset owners a wide range of data, deployed at different levels that can be used to support operator situation awareness. However, the sheer amount of data available can make it challenging for operators to assimilate information and respond appropriately. This paper reviews some of the challenges and issues associated with providing operators with actionable state awareness and argues for the over arching importance of integrating human factors as part of intelligent control systems design and implementation. It is argued that system resilience is improved by implementing human factors in operations and maintenance. This paper also introduces issues associated with resilience and data fusion and highlights areas in which human factors including field studies hold promise.

Abstracts of the 23rd European physical society conference on controlled fusion and plasma physics

Energy Technology Data Exchange (ETDEWEB)

Goutych, I F; Gresillon, D; Sitenko, A G

1997-12-31

This document contains the abstracts of the invited and contributed papers presented at 23 EPS conference on controlled fusion and plasma physics. The main contents are: tokamaks, stellarators; alternative magnetic confinement; plasma edge physics; plasma heating and current drive; plasma diagnostics; basic collisionless plasma physics; high intensity laser produced plasmas and inertial confinement; low-temperature plasmas.

Abstracts of the 23rd European physical society conference on controlled fusion and plasma physics

International Nuclear Information System (INIS)

Goutych, I.F.; Gresillon, D.; Sitenko, A.G.

1996-01-01

This document contains the abstracts of the invited and contributed papers presented at 23 EPS conference on controlled fusion and plasma physics. The main contents are: tokamaks, stellarators; alternative magnetic confinement; plasma edge physics; plasma heating and current drive; plasma diagnostics; basic collisionless plasma physics; high intensity laser produced plasmas and inertial confinement; low-temperature plasmas

A Survey on Optimal Signal Processing Techniques Applied to Improve the Performance of Mechanical Sensors in Automotive Applications

Directory of Open Access Journals (Sweden)

Wilmar Hernandez

2007-01-01

Full Text Available In this paper a survey on recent applications of optimal signal processing techniques to improve the performance of mechanical sensors is made. Here, a comparison between classical filters and optimal filters for automotive sensors is made, and the current state of the art of the application of robust and optimal control and signal processing techniques to the design of the intelligent (or smart sensors that today’s cars need is presented through several experimental results that show that the fusion of intelligent sensors and optimal signal processing techniques is the clear way to go. However, the switch between the traditional methods of designing automotive sensors and the new ones cannot be done overnight because there are some open research issues that have to be solved. This paper draws attention to one of the open research issues and tries to arouse researcher’s interest in the fusion of intelligent sensors and optimal signal processing techniques.

Energy from inertial fusion

International Nuclear Information System (INIS)

1995-03-01

This book contains 22 articles on inertial fusion energy (IFE) research and development written in the framework of an international collaboration of authors under the guidance of an advisory group on inertial fusion energy set up in 1991 to advise the IAEA. It describes the actual scientific, engineering and technological developments in the field of inertial confinement fusion (ICF). It also identifies ways in which international co-operation in ICF could be stimulated. The book is intended for a large audience and provides an introduction to inertial fusion energy and an overview of the various technologies needed for IFE power plants to be developed. It contains chapters on (i) the fundamentals of IFE; (ii) inertial confinement target physics; (iii) IFE power plant design principles (requirements for power plant drivers, solid state laser drivers, gas laser drivers, heavy ion drivers, and light ion drivers, target fabrication and positioning, reaction chamber systems, power generation and conditioning and radiation control, materials management and target materials recovery), (iv) special design issues (radiation damage in structural materials, induced radioactivity, laser driver- reaction chamber interfaces, ion beam driver-reaction chamber interfaces), (v) inertial fusion energy development strategy, (vi) safety and environmental impact, (vii) economics and other figures of merit; (viii) other uses of inertial fusion (both those involving and not involving implosions); and (ix) international activities. Refs, figs and tabs

Contributions to the 20. EPS conference on controlled fusion and plasma physics

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-07-15

The Conference covers research on different aspects of plasma physics and fusion technology, like technical aspects of Tokamak devices; plasma instabilities and impurities, development and testing of materials for fusion reactors etc.

Progress of laser fusion at Lawrence Livermore Laboratory

Energy Technology Data Exchange (ETDEWEB)

Ahlstrom, H G [California Univ., Livermore (USA). Lawrence Livermore Lab.

1979-01-01

Inertial confinement fusion is the present and future source of energy in our universe. Derivatives, such as solar, geothermal, wind, and biomass are proposed as future substitutes for possible fuel sources. All of these possible sources of energy while they may be considered to be renewable do not fulfill the single most important criteria of being unlimited. Fuel reserves of more than 100 billion years are accepted as 'unlimited'. The understanding of fusion has many 'fathers', Bethe, Teller and many others, it has also has proponents (too many to list) as the world's energy supply. This author hopes that this Program's efforts will contribute positively to the advance to the time when fusion energy will positively contribute to the energy supply for mankind. Controlled fusion is judged by us to be the world's most challenging technological problem. The potential benefit to mankind of an unlimited source of energy and thus a higher standard of living make the acceptance of this challenge worth our while. There are many dedicated scientists working on controlled fusion to make this dream a reality. Magnetic and inertial fusion are in a horse race that must not be allowed to falter or to be cancelled. Fusion is the future of the world and one of these approaches to fusion is vital to our future generations.

Progress of laser fusion at Lawrence Livermore Laboratory

International Nuclear Information System (INIS)

Ahlstrom, H.G.

1979-01-01

Inertial confinement fusion is the present and future source of energy in our universe. Derivatives, such as solar, geothermal, wind, and biomass are proposed as future substitutes for possible fuel sources. All of these possible sources of energy while they may be considered to be renewable do not fulfill the single most important criteria of being unlimited. Fuel reserves of more than 100 billion years are accepted as 'unlimited'. The understanding of fusion has many 'fathers', Bethe, Teller and many others, it has also has proponents (too many to list) as the world's energy supply. This author hopes that this Program's efforts will contribute positively to the advance to the time when fusion energy will positively contribute to the energy supply for mankind. Controlled fusion is judged by us to be the world's most challenging technological problem. The potential benefit to mankind of an unlimited source of energy and thus a higher standard of living make the acceptance of this challenge worth our while. There are many dedicated scientists working on controlled fusion to make this dream a reality. Magnetic and inertial fusion are in a horse race that must not be allowed to falter or to be cancelled. Fusion is the future of the world and one of these approaches to fusion is vital to our future generations

EURATOM-CEA association. Controlled fusion. Management committee nr 79. Activity report. National collaborations (Universities and CNRS). November 2007 - October 2005

International Nuclear Information System (INIS)

Garbet, X.; Benkadda, S.; Ottaviani, M.; Escande, D.; Blum, J.; Brenier, Y.; Lutjens, H.; Ghendrih, Ph.; Lima, R.; Bertrand, P.; Firpo, M.C.

2005-12-01

This publication presents several research projects on controlled fusion lead in collaboration by CNRS and academic teams. The general framework of these projects concerns theoretical developments in gyro-kinetics, transport and equilibrium to develop the required tools for the modelling of fusing plasmas. It comprises a study of characterisation and control of turbulent transport in tokamak plasmas, a study on the magnetic self-organisation of fusing plasmas, a gyro-kinetic modelling of tokamak plasmas, a study of identification and optimal control of plasma equilibrium in a tokamak, a gyrokinetic approach to the Vlasov equation, a study of the linear and non linear dynamics of instability modes in a tokamak plasma by using the model of extended magnetohydrodynamics, a study of the control of turbulence in magnetic fusion plasmas, and a study of the non linear regime of the n=1, m=1 mode

Prospects for Tokamak Fusion Reactors

International Nuclear Information System (INIS)

Sheffield, J.; Galambos, J.

1995-01-01

This paper first reviews briefly the status and plans for research in magnetic fusion energy and discusses the prospects for the tokamak magnetic configuration to be the basis for a fusion power plant. Good progress has been made in achieving fusion reactor-level, deuterium-tritium (D-T) plasmas with the production of significant fusion power in the Joint European Torus (up to 2 MW) and the Tokamak Fusion Test Reactor (up to 10 MW) tokamaks. Advances on the technologies of heating, fueling, diagnostics, and materials supported these achievements. The successes have led to the initiation of the design phases of two tokamaks, the International Thermonuclear Experimental Reactor (ITER) and the US Toroidal Physics Experiment (TPX). ITER will demonstrate the controlled ignition and extended bum of D-T plasmas with steady state as an ultimate goal. ITER will further demonstrate technologies essential to a power plant in an integrated system and perform integrated testing of the high heat flux and nuclear components required to use fusion energy for practical purposes. TPX will complement ITER by testing advanced modes of steady-state plasma operation that, coupled with the developments in ITER, will lead to an optimized demonstration power plant

Analysis of membrane fusion as a two-state sequential process: evaluation of the stalk model.

Science.gov (United States)

Weinreb, Gabriel; Lentz, Barry R

2007-06-01

We propose a model that accounts for the time courses of PEG-induced fusion of membrane vesicles of varying lipid compositions and sizes. The model assumes that fusion proceeds from an initial, aggregated vesicle state ((A) membrane contact) through two sequential intermediate states (I(1) and I(2)) and then on to a fusion pore state (FP). Using this model, we interpreted data on the fusion of seven different vesicle systems. We found that the initial aggregated state involved no lipid or content mixing but did produce leakage. The final state (FP) was not leaky. Lipid mixing normally dominated the first intermediate state (I(1)), but content mixing signal was also observed in this state for most systems. The second intermediate state (I(2)) exhibited both lipid and content mixing signals and leakage, and was sometimes the only leaky state. In some systems, the first and second intermediates were indistinguishable and converted directly to the FP state. Having also tested a parallel, two-intermediate model subject to different assumptions about the nature of the intermediates, we conclude that a sequential, two-intermediate model is the simplest model sufficient to describe PEG-mediated fusion in all vesicle systems studied. We conclude as well that a fusion intermediate "state" should not be thought of as a fixed structure (e.g., "stalk" or "transmembrane contact") of uniform properties. Rather, a fusion "state" describes an ensemble of similar structures that can have different mechanical properties. Thus, a "state" can have varying probabilities of having a given functional property such as content mixing, lipid mixing, or leakage. Our data show that the content mixing signal may occur through two processes, one correlated and one not correlated with leakage. Finally, we consider the implications of our results in terms of the "modified stalk" hypothesis for the mechanism of lipid pore formation. We conclude that our results not only support this hypothesis but

Nuclear fusion: power for the next century

International Nuclear Information System (INIS)

1980-05-01

The basis of fusion reactions is outlined, with special reference to deuterium and tritium (from lithium, by neutron reaction) as reactants, and the state of research worldwide is indicated. The problems inherent in fusion reactions are discussed, plasma is defined, and the steps to be taken to generate electricity from controlled nuclear fusion are stated. Methods of plasma heating and plasma confinement are considered, leading to a description of the tokamak plasma confinement system. Devices under construction include the JET (Joint European Torus) Undertaking in the UK. Plans and possibilities for fusion reactors are discussed. (U.K.)

Nuclear Fusion Research Understanding Plasma-Surface Interactions

CERN Document Server

Clark, Robert E.H

2005-01-01

It became clear in the early days of fusion research that the effects of the containment vessel (erosion of "impurities") degrade the overall fusion plasma performance. Progress in controlled nuclear fusion research over the last decade has led to magnetically confined plasmas that, in turn, are sufficiently powerful to damage the vessel structures over its lifetime. This book reviews current understanding and concepts to deal with this remaining critical design issue for fusion reactors. It reviews both progress and open questions, largely in terms of available and sought-after plasma-surface interaction data and atomic/molecular data related to these "plasma edge" issues.

A review of hedgehog signaling in cranial bone development

Directory of Open Access Journals (Sweden)

Angel ePan

2013-04-01

Full Text Available During craniofacial development, the Hedgehog (HH signaling pathway is essential for mesodermal tissue patterning and differentiation. The Hedgehog family consists of three protein ligands: Sonic Hedgehog (SHH, Indian Hedgehog (IHH, and Desert Hedgehog (DHH, of which two are expressed in the craniofacial complex (IHH and SHH. Dysregulations in HH signaling are well documented to result in a wide range of craniofacial abnormalities, including holoprosencephaly, hypotelorism, and cleft lip/palate. Furthermore, mutations in HH effectors, co-receptors, and ciliary proteins result in skeletal and craniofacial deformities. Cranial suture morphogenesis is a delicate developmental process that requires control of cell commitment, proliferation and differentiation. This review focuses on both what is known and what remains unknown regarding HH signaling in cranial suture morphogenesis and intramembranous ossification. As demonstrated from murine studies, expression of both SHH and IHH is critical to the formation and fusion of the cranial sutures and calvarial ossification. SHH expression has been observed in the cranial suture mesenchyme and its precise function is not fully defined, although some postulate SHH to delay cranial suture fusion. IHH expression is mainly found on the osteogenic fronts of the calvarial bones, and functions to induce cell proliferation and differentiation. Unfortunately, neonatal lethality of deficient mice precludes a detailed examination of their postnatal calvarial phenotype. In summary, a number of basic questions are yet to be answered regarding domains of expression, developmental role, and functional overlap of HH morphogens in the calvaria. Nevertheless, SHH and IHH ligands are integral to cranial suture development and regulation of calvarial ossification. When HH signaling goes awry, the resultant suite of morphologic abnormalities highlights the important roles of HH signaling in cranial development.

Controlled Nuclear Fusion by Magnetic Confinement and ITER

CERN Document Server

CERN. Geneva. Audiovisual Unit; Alvarez-Gaumé, Luís

2005-01-01

For may years harnessing fusion energy was considered the final solution to the world's energy crisis. ITER is the last step in the elusive quest. This presentation will provide in its various acientific, technological and political aspects.

Fusion energy

International Nuclear Information System (INIS)

Gross, R.A.

1984-01-01

This textbook covers the physics and technology upon which future fusion power reactors will be based. It reviews the history of fusion, reaction physics, plasma physics, heating, and confinement. Descriptions of commercial plants and design concepts are included. Topics covered include: fusion reactions and fuel resources; reaction rates; ignition, and confinement; basic plasma directory; Tokamak confinement physics; fusion technology; STARFIRE: A commercial Tokamak fusion power plant. MARS: A tandem-mirror fusion power plant; and other fusion reactor concepts

Suppression of hydrogenated carbon film deposition by scavenger techniques and their application to the tritium inventory control of fusion devices

International Nuclear Information System (INIS)

Tabares, F.L.; Tafalla, D.; Tanarro, I.; Herrero, V.J.; Islyaikin, A.; Maffiotte, C.

2002-01-01

The well-known radical and ion scavenger techniques of application in amorphous hydrogenated carbon film deposition studies are investigated in relation to the mechanism of tritium and deuterium co-deposition in carbon-dominated fusion devices. A particularly successful scheme results from the injection of nitrogen into methane/hydrogen plasmas for conditions close to those prevailing in the divertor region of present fusion devices. A complete suppression of the a-C : H film deposition has been achieved for N 2 /CH 4 ratios close to one in methane (5%)/hydrogen DC plasma. The implications of these findings in the tritium retention control in future fusion reactors are addressed. (author). Letter-to-the-editor

Fusion Power Program biannual progress report, April-September 1979

International Nuclear Information System (INIS)

1980-02-01

This biannual report summarizes the Argonne National Laboratory work performed for the Office of Fusion Energy during the April-September 1979 quarter in the following research and development areas: materials; energy storage and transfer; tritium containment, recovery and control; advanced reactor design; atomic data; reactor safety; fusion-fission hybrid systems; alternate applications of fusion energy; and other work related to fusion power. Separate abstracts were prepared for three sections

ORNL's Controlled Fusion Atomic Data Center

International Nuclear Information System (INIS)

Barnett, C.F.; Gregory, D.C.

1983-01-01

The Data Center maintains a detailed bibliography of atomic data measurements and calculations for processes of interest to the fusion community. One hundred nineteen journals are regularly searched for papers of interest, including back issues to 1950. Entries are categorized by author, process, reactants, energy range, and theory/experiment. Complete bibliographies have been published since 1978 and a computerized data retrieval system is available. In addition, an updated and extended multi-volume critical compilation of cross sections (the ORNL Redbooks) is under way

Annual progress report 1993. Work in controlled thermonuclear fusion research performed in the fusion research unit under the contract of association between Euratom and Risoe National Laboratory

International Nuclear Information System (INIS)

1994-09-01

The programme of the Research Unit of the Fusion Association Euratom-Risoe National Laboratory covers work in fusion plasma physics and in fusion technology. The fusion plasma physics group has activities within (a) studies of nonlinear dynamical processes in magnetized plasmas, (b) development of pellet injectors for fusion experiments, and (c) development of diagnostics for fusion plasmas. The activities in technology cover radiation damage of fusion reactor materials. A summary of the activities in 1993 is presented. (au) (4 tabs., 21 ills., 64 refs.)

Osteoclast Fusion

DEFF Research Database (Denmark)

Marie Julie Møller, Anaïs; Delaissé, Jean-Marie; Søe, Kent

2017-01-01

on the nuclearity of fusion partners. While CD47 promotes cell fusions involving mono-nucleated pre-osteoclasts, syncytin-1 promotes fusion of two multi-nucleated osteoclasts, but also reduces the number of fusions between mono-nucleated pre-osteoclasts. Furthermore, CD47 seems to mediate fusion mostly through...... individual fusion events using time-lapse and antagonists of CD47 and syncytin-1. All time-lapse recordings have been studied by two independent observers. A total of 1808 fusion events were analyzed. The present study shows that CD47 and syncytin-1 have different roles in osteoclast fusion depending...... broad contact surfaces between the partners' cell membrane while syncytin-1 mediate fusion through phagocytic-cup like structure. J. Cell. Physiol. 9999: 1-8, 2016. © 2016 Wiley Periodicals, Inc....

Drosophila Cancer Models Identify Functional Differences between Ret Fusions.

Science.gov (United States)

Levinson, Sarah; Cagan, Ross L

2016-09-13

We generated and compared Drosophila models of RET fusions CCDC6-RET and NCOA4-RET. Both RET fusions directed cells to migrate, delaminate, and undergo EMT, and both resulted in lethality when broadly expressed. In all phenotypes examined, NCOA4-RET was more severe than CCDC6-RET, mirroring their effects on patients. A functional screen against the Drosophila kinome and a library of cancer drugs found that CCDC6-RET and NCOA4-RET acted through different signaling networks and displayed distinct drug sensitivities. Combining data from the kinome and drug screens identified the WEE1 inhibitor AZD1775 plus the multi-kinase inhibitor sorafenib as a synergistic drug combination that is specific for NCOA4-RET. Our work emphasizes the importance of identifying and tailoring a patient's treatment to their specific RET fusion isoform and identifies a multi-targeted therapy that may prove effective against tumors containing the NCOA4-RET fusion. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Decentralized Hierarchical Controller Design for Selective Damping of Inter Area Oscillations Using PMU Signals

Directory of Open Access Journals (Sweden)

Ashfaque Ahmed Hashmani

2011-07-01

Full Text Available This paper deals with the decentralized hierarchical PSS (Power System Stabilizer controller design to achieve a better damping of specific inter-area oscillations. The two-level decentralized hierarchical structure consists of two PSS controllers. The first level controller is a local PSS controller for each generator to damp local mode in the area where controller is located. This controller uses only local signals as input signals. The local signal comes from the generator at which the controller is located. The secondary level controller is a multivariable decentralized global PSS controller to damp inter-area modes. This controller uses selected suitable wide area PMU (Phasor Measurement Units signals as inputs. The PMU or global signals are taken from network locations where the oscillations are well observable. The global controller uses only those global input signals in which the assigned single inter-area mode is most observable and is located at a generator that is most effective in controlling the assigned mode. The global controller works mainly in a frequency band given by the natural frequency of the assigned mode. The effectiveness of the resulting hierarchical controller is demonstrated through simulation studies conducted on a test power system.

Diagnostics considerations for the inertial confinement approach to controlled thermonuclear fusion power production

International Nuclear Information System (INIS)

Wood, L.

1978-01-01

It is concluded that although the challenges facing diagnosticians working on the inertial confinement approach to controlled fusion are large and varied, the means potentially available to meet them are more than adequate. No new instrumentation fields need be opened; rather, substantial extensions of those already being explored by workers in ICF will suffice. Also, large contributions may be expected from other technological applications thrusts, as well as from the general, currently rapid advance of the entire physical technology base

Correlation measurements for fusion plasma diagnostics

International Nuclear Information System (INIS)

Pazsit, I.

1995-01-01

A list of a few methods for plasma diagnostics via fluctuations (noise) analysis of random (both temporally and spatially) system parameters is reviewed. Analogy is drawn with certain noise analysis methods, used in the diagnostics of fission reactors. These methods have been applied also to fusion measurements to some extent. However, the treatment of fusion plasma fluctuations is dominated by an approach that allows for temporal randomness, but assumes periodicity in space. This approach suits well a large class of phenomena such as magnetic fluctuations (MHD effects), but is much less suited to treat localised effects such as turbulence and density fluctuations. This paper discusses the potentials of the former approach, i.e. ordinary noise analysis methods of non-periodic variables in fusion plasma diagnostics. A new recommendation is to use the crossed beam correlation analysis of soft X-ray signals for determining the local short-range correlations in the plasma and to perform a systematic exploration of the plasma spatial correlation structure with that and other methods. 16 refs, 7 figs

Compressed Sensing and Low-Rank Matrix Decomposition in Multisource Images Fusion

Directory of Open Access Journals (Sweden)

Kan Ren

2014-01-01

Full Text Available We propose a novel super-resolution multisource images fusion scheme via compressive sensing and dictionary learning theory. Under the sparsity prior of images patches and the framework of the compressive sensing theory, the multisource images fusion is reduced to a signal recovery problem from the compressive measurements. Then, a set of multiscale dictionaries are learned from several groups of high-resolution sample image’s patches via a nonlinear optimization algorithm. Moreover, a new linear weights fusion rule is proposed to obtain the high-resolution image. Some experiments are taken to investigate the performance of our proposed method, and the results prove its superiority to its counterparts.

A user configurable data acquisition and signal processing system for high-rate, high channel count applications

International Nuclear Information System (INIS)

Salim, Arwa; Crockett, Louise; McLean, John; Milne, Peter

2012-01-01

Highlights: ► The development of a new digital signal processing platform is described. ► The system will allow users to configure the real-time signal processing through software routines. ► The architecture of the DRUID system and signal processing elements is described. ► A prototype of the DRUID system has been developed for the digital chopper-integrator. ► The results of acquisition on 96 channels at 500 kSamples/s per channel are presented. - Abstract: Real-time signal processing in plasma fusion experiments is required for control and for data reduction as plasma pulse times grow longer. The development time and cost for these high-rate, multichannel signal processing systems can be significant. This paper proposes a new digital signal processing (DSP) platform for the data acquisition system that will allow users to easily customize real-time signal processing systems to meet their individual requirements. The D-TACQ reconfigurable user in-line DSP (DRUID) system carries out the signal processing tasks in hardware co-processors (CPs) implemented in an FPGA, with an embedded microprocessor (μP) for control. In the fully developed platform, users will be able to choose co-processors from a library and configure programmable parameters through the μP to meet their requirements. The DRUID system is implemented on a Spartan 6 FPGA, on the new rear transition module (RTM-T), a field upgrade to existing D-TACQ digitizers. As proof of concept, a multiply-accumulate (MAC) co-processor has been developed, which can be configured as a digital chopper-integrator for long pulse magnetic fusion devices. The DRUID platform allows users to set options for the integrator, such as the number of masking samples. Results from the digital integrator are presented for a data acquisition system with 96 channels simultaneously acquiring data at 500 kSamples/s per channel.

Bandwidths of micro-twisted-pair cables and fusion-spliced SIMM-GRIN fiber

International Nuclear Information System (INIS)

Gan, K.K.; Kagan, H.P.; Kass, R.D.; Smith, D.S.

2007-01-01

The SLHC is designed to increase the luminosity of the LHC by a factor of 10. In the present ATLAS pixel detector, electrical signals between the pixel modules and the optical modules (opto-boards) are transmitted in ∼1 m of micro-twisted-pair cables. The optical signals between the opto-boards and the off-detector optical modules are transmitted in fiber ribbons. Each fiber link consists of 8 m of rad-hard/low bandwidth SIMM fiber fusion spliced to 70 m of rad-tolerant/medium bandwidth GRIN fiber. We currently transmit optical signals at 80 Mb/s and expect to transmit signals at 1 Gb/s in the SLHC. For the SLHC optical link, we would like to take advantage of some of the design features of the present pixel optical links and the many years of R and D effort and production experience. If the present architecture can transmit signals at the higher speed required by the SLHC, the constraint of requiring no extra service space is automatically satisfied. We have measured the bandwidths of the transmission lines and our preliminary results indicate that the micro-twisted-pair cables can transmit signals up to ∼1 Gb/s and the fusion-spliced fiber ribbon can transmit signals up to ∼2 Gb/s

Long-term planning frame of controlled fusion research in the Federal Republic of Germany and within the scope of EURATOM

International Nuclear Information System (INIS)

1989-01-01

Current R and D activities in the field of controlled nuclear fusion are investigating physics and technological problems rather than economic efficiency aspects of future fusion reactor systems. The report in hand compares the long-term plans and programmes set up on the European level with other countries' programmes, explains the international cooperative framework and activities, and goes into details of the Federal German research programme. Aspects of safety and environmental impacts are discussed. (HP) [de

Utilization of a Network of Small Magnetic Confinement Fusion Devices for Mainstream Fusion Research. Report of a Coordinated Research Project 2011–2016

International Nuclear Information System (INIS)

2016-12-01

The IAEA actively promotes the development of controlled fusion as a source of energy. Through its coordinated research activities, the IAEA helps Member States to exchange and establish scientific and technical knowledge required for the design, construction and operation of a fusion reactor. Due to their compactness, flexibility and low operation costs, small fusion devices are a great resource for supporting and accelerating the development of mainstream fusion research on large fusion devices such as the International Thermonuclear Experimental Reactor. They play an important role in investigating the physics of controlled fusion, developing innovative technologies and diagnostics, testing new materials, training highly qualified personnel for larger fusion facilities, and supporting educational programmes for young scientists. This publication reports on the research work accomplished within the framework of the Coordinated Research Project (CRP) on Utilization of the Network of Small Magnetic Confinement Fusion Devices for Mainstream Fusion Research, organized and conducted by the IAEA in 2011–2016. The CRP has contributed to the coordination of a network of research institutions, thereby enhancing international collaboration through scientific visits, joint experiments and the exchange of information and equipment. A total of 16 institutions and 14 devices from 13 Member States participated in this CRP (Belgium, Bulgaria, Canada, China, Costa Rica, the Czech Republic, the Islamic Republic of Iran, Kazakhstan, Pakistan, Portugal, the Russian Federation, Ukraine and the United Kingdom).

Plasma physics and controlled nuclear fusion research 1994. V. 3. Proceedings of the fifteenth international conference

International Nuclear Information System (INIS)

1996-01-01

This is the third volume of the proceedings of the 15th International Atomic Energy Agency Conference on Plasma Physics and Controlled Nuclear Fusion Research held in Seville, Spain, from 26 September - 1 October 1994. Contained in it are 29 papers on inertial confinement and 46 papers on magnetic confinement. Refs, figs, tabs

State of controlled nuclear fusion research

International Nuclear Information System (INIS)

Rodrigo, A.B.

1978-04-01

The development of a commercial fusion reactor requires an adequate solution to the problems of heating and confinement of the nuclear fuel, as well as a considerable effort in materials technology and reactor engineering. A general discussion is presented of the status of the research connected with the most advanced concepts, indicating in each case the present situation and the main problems that must be solved to meet the requeriments estimated for power reactors. In particular, the laser-inertial concept is reviewed in detail. (author) [es

Material for fusion reactor

International Nuclear Information System (INIS)

Abhishek, Anuj; Ranjan, Prem

2011-01-01

To make nuclear fusion power a reality, the scientists are working restlessly to find the materials which can confine the power generated by the fusion of two atomic nuclei. A little success in this field has been achieved, though there are still miles to go. Fusion reaction is a special kind of reaction which must occur at very high density and temperature to develop extremely large amount of energy, which is very hard to control and confine within using the present techniques. As a whole it requires the physical condition that rarely exists on the earth to carry out in an efficient manner. As per the growing demand and present scenario of the world energy, scientists are working round the clock to make effective fusion reactions to real. In this paper the work presently going on is considered in this regard. The progress of the Joint European Torus 2010, ITER 2005, HiPER and minor works have been studied to make the paper more object oriented. A detailed study of the technological and material requirement has been discussed in the paper and a possible suggestion is provided to make a contribution in the field of building first ever nuclear fusion reactor

Control of activation levels to simplify waste management of fusion reactor ferritic steel components

International Nuclear Information System (INIS)

Wiffen, F.W.; Santoro, R.T.

1983-01-01

Activation characteristics of a material for service in the neutron flux of a fusion reactor first wall fall into three areas: waste management, reactor maintenance and repair, and safety. Of these, the waste management area is the most likely to impact the public acceptance of fusion reactors for power generation. The decay of the activity in steels within tens of years could lead to simplified waste disposal or possibly even to materials recycle. Whether or not these can be achieved will be controlled by (1) selection of alloying elements, (2) control of critical impurity elements, and (3) control of cross contamination from other reactor components. Several criteria can be used to judge the acceptability of potential alloying elements in iron, and to define the limits on content of critical impurity elements. One approach is to select and limit alloying additions on the basis of the activity. If material recycle is a goal, N, Al, Ni, Cu, Nb, and Mo must be excluded. If simplified waste storage by shallow land burial is the goal, regulations limit the concentration of only a few isotopes. For first-wall material that will be exposed to 9 MW-y/m 2 service, allowable initial concentration limits include (in at. ppM) Ni < 20,000; Mo < 3650; N < 3650, Cu < 2400; and Nb < 1.0. The other constituent elements of ferritic steels will not be limited. Possible substitutes for the molybdenum normally used to strengthen the steels include W, Ta, Ti, and V

Design of Lamifuse: a randomised, multi-centre controlled trial comparing laminectomy without or with dorsal fusion for cervical myeloradiculopathy

Directory of Open Access Journals (Sweden)

Grotenhuis J André

2007-11-01

Full Text Available Abstract Background laminectomy is a valuable surgical treatment for some patients with a cervical radiculomyelopathy due to cervical spinal stenosis. More recently attention has been given to motion of the spinal cord over spondylotic spurs as a cause of myelopathic changes. Immobilisation by fusion could have a positive effect on the recovery of myelopathic signs or changes. This has never been investigated in a prospective, randomised trial. Lamifuse is an acronyme for laminectomy and fusion. Methods/Design Lamifuse is a multicentre, randomised controlled trial comparing laminectomy with and without fusion in patients with a symptomatic cervical canal stenosis. The study population will be enrolled from patients that are 60 years or older with myelopathic signs and/or symptoms due to a cervical canal stenosis. A kyphotis shape of the cervical spine is an exclusion criterium. Each treatment arm needs 30 patients. Discussion This study will contribute to the discussion whether additional fusion after a cervical laminectomy results in a better clinical outcome. ISRCT number ISRCTN72800446

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy.

Science.gov (United States)

Goh, Qingnian; Millay, Douglas P

2017-02-10

Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored. In response to muscle overload after synergist ablation in mice, we show that myomaker, a muscle specific membrane protein essential for myoblast fusion, is activated mainly in muscle progenitors and not myofibers. We rendered muscle progenitors fusion-incompetent through genetic deletion of myomaker in muscle stem cells and observed a complete reduction of overload-induced hypertrophy. This blunted hypertrophic response was associated with a reduction in Akt and p70s6k signaling and protein synthesis, suggesting a link between myonuclear accretion and activation of pro-hypertrophic pathways. Furthermore, fusion-incompetent muscle exhibited increased fibrosis after muscle overload, indicating a protective role for normal stem cell activity in reducing myofiber strain associated with hypertrophy. These findings reveal an essential contribution of myomaker-mediated stem cell fusion during physiological adult muscle hypertrophy.

Confusion about nuclear fusion: a false report is laid bare

International Nuclear Information System (INIS)

Hintsches, E.

1983-01-01

The author discusses the inaccurate and precipitate news of alleged successful controlled nuclear fusion in the Tokamak Fusion Test Reactor at Princeton University. The later modified published report indicated that in a first test, fractional second operation had produced plasma gas temperature of 100,000 0 C whereas 100 million degrees C is necessary for hydrogen nuclear fusion. Also power generation from nuclear fusion is still a long term goal. Problems of nuclear fusion are very briefly mentioned, and an impression of the Tokamak Fusion Test Reactor is illustrated. (H.V.H.)

Intersection signal control multi-objective optimization based on genetic algorithm

Directory of Open Access Journals (Sweden)

Zhanhong Zhou

2014-04-01

Full Text Available A signal control intersection increases not only vehicle delay, but also vehicle emissions and fuel consumption in that area. Because more and more fuel and air pollution problems arise recently, an intersection signal control optimization method which aims at reducing vehicle emissions, fuel consumption and vehicle delay is required heavily. This paper proposed a signal control multi-object optimization method to reduce vehicle emissions, fuel consumption and vehicle delay simultaneously at an intersection. The optimization method combined the Paramics microscopic traffic simulation software, Comprehensive Modal Emissions Model (CMEM, and genetic algorithm. An intersection in Haizhu District, Guangzhou, was taken for a case study. The result of the case study shows the optimal timing scheme obtained from this method is better than the Webster timing scheme.

Control and data management for a large fusion laser

International Nuclear Information System (INIS)

Davis, J.W.; Holloway, F.W.

1975-01-01

SHIVA is a powerful (10-kJ 25 TW) neodymium glass laser system to be used (in 1977) for target irradiation in fusion research. SHIVA is also a development project in that it is pushing the state of the art in laser and optical technology. The present design calls for 20 parallel laser amplification chains whose light output is pointed and focused at a small (100 μ) target within a chamber from semi-equally spaced three-dimensional directions. It is probable that SHIVA will be upgraded to as many as 42 chains in the next few years. Each chain of SHIVA contains 7 high energy laser amplifiers and perhaps 20 other major optical components, many of which send and receive control and measurement information. Again future expansion may add additional elements. Each chain has also associated 10 gimbal or translation motions for beam assignment from the oscillator onto the target

Quantum propagator approach to heavy-ion fusion

International Nuclear Information System (INIS)

Bao, J.D.

2002-01-01

The real-time path integral propagator approach is used to study the fusion probability of massive nuclei including quantum effect. An analytical expression of the probability to pass over barrier of an inverted harmonic potential is obtained, in which both height and curvature of the barrier are controlled by the neck degree of freedom. The fusion probability of three systems in central collision as a function of the center of mass energy are calculated and compared to experimental results. It is shown that the quantum fluctuation enhances the fusion probability at low energies, and the neck fluctuation makes the slope of the fusion probability curve become flatter. (author)

Warts signaling controls organ and body growth through regulation of ecdysone

DEFF Research Database (Denmark)

Møller, Morten Erik; Nagy, Stanislav; Gerlach, Stephan Uwe

2017-01-01

Coordination of growth between individual organs and the whole body is essential during development to produce adults with appropriate size and proportions [1, 2]. How local organ-intrinsic signals and nutrient-dependent systemic factors are integrated to generate correctly proportioned organisms...... under different environmental conditions is poorly understood. In Drosophila, Hippo/Warts signaling functions intrinsically to regulate tissue growth and organ size [3, 4], whereas systemic growth is controlled via antagonistic interactions of the steroid hormone ecdysone and nutrient-dependent insulin....../insulin-like growth factor (IGF) (insulin) signaling [2, 5]. The interplay between insulin and ecdysone signaling regulates systemic growth and controls organismal size. Here, we show that Warts (Wts; LATS1/2) signaling regulates systemic growth in Drosophila by activating basal ecdysone production, which negatively...

New trends in fusion research

CERN Multimedia

CERN. Geneva

2004-01-01

The efforts of the international fusion community aim at demonstrating the scientific feasibility of thermonuclear fusion energy power plants. Understanding the behavior of burning plasmas, i.e. plasmas with strong self-heating, represents a primary scientific challenge for fusion research and a new science frontier. Although integrated studies will only be possible, in new, dedicated experimental facilities, such as the International Tokamak Experimental Reactor (ITER), present devices can address specific issues in regimes relevant to burning plasmas. Among these are an improvement of plasma performance via a reduction of the energy and particle transport, an optimization of the path to ignition or to sustained burn using additional heating and a control of plasma-wall interaction and energy and particle exhaust. These lectures address recent advances in plasma science and technology that are relevant to the development of fusion energy. Mention will be made of the inertial confinement line of research, but...

Tritium accountancy in fusion systems

Energy Technology Data Exchange (ETDEWEB)

Klein, J.E.; Clark, E.A.; Harvel, C.D.; Farmer, D.A.; Tovo, L.L.; Poore, A.S. [Savannah River National Laboratory, Aiken, SC (United States); Moore, M.L. [Savannah River Nuclear Solutions, Aiken, SC (United States)

2015-03-15

The US Department of Energy (DOE) has clearly defined requirements for nuclear material control and accountability (MCA) of tritium whereas the International Atomic Energy Agency (IAEA) does not since tritium is not a fissile material. MCA requirements are expected for tritium fusion machines and will be dictated by the host country or regulatory body where the machine is operated. Material Balance Areas (MBA) are defined to aid in the tracking and reporting of nuclear material movements and inventories. Material sub-accounts (MSA) are established along with key measurement points (KMP) to further subdivide a MBA to localize and minimize uncertainties in the inventory difference (ID) calculations for tritium accountancy. Fusion systems try to minimize tritium inventory which may require continuous movement of material through the MSA. The ability of making meaningful measurements of these material transfers is described in terms of establishing the MSA structure to perform and reconcile ID calculations. For fusion machines, changes to the traditional ID equation will be discussed which includes breeding, burn-up, and retention of tritium in the fusion device. The concept of 'net' tritium quantities consumed or lost in fusion devices is described in terms of inventory taking strategies and how it is used to track the accumulation of tritium in components or fusion machines. (authors)

Fusion

CERN Document Server

Mahaffey, James A

2012-01-01

As energy problems of the world grow, work toward fusion power continues at a greater pace than ever before. The topic of fusion is one that is often met with the most recognition and interest in the nuclear power arena. Written in clear and jargon-free prose, Fusion explores the big bang of creation to the blackout death of worn-out stars. A brief history of fusion research, beginning with the first tentative theories in the early 20th century, is also discussed, as well as the race for fusion power. This brand-new, full-color resource examines the various programs currently being funded or p

Development of remote control software for multiformat test signal generator

Directory of Open Access Journals (Sweden)

Gao Yang

2017-01-01

Full Text Available The multi format test signal generator mentioned in this paper is the video signal generator named TG8000 produced by Tektronix Company. I will introduce the function about remote control for signal generator, how to connect the computer to the instrument, and how to remote control. My topic uses my computer to connect the instrument through the 10/100/1000 BASE-T port on the rear panel of TG8000. Then I write program to transmit SCPI (Standard Commands for Programmable Instruments to control TG8000. The application is running on the Windows operating system, the programming language is C#, development environment is Microsoft Visual Studio 2010, using the TCP/IP protocol based on Socket. And the method of remote control refers to the application called TGSetup which is developed by Tektronix Company. This paper includes a brief summary of the basic principle, and introduce for details about the process of remote control software development, and how to use my software. In the end, I will talk about the advantages of my software compared with another one.

Human placental trophoblast invasion and differentiation: a particular focus on Wnt signalling

Directory of Open Access Journals (Sweden)

Martin eKnöfler

2013-09-01

Full Text Available Wingless ligands, a family of secreted proteins, are critically involved in organ development and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and differentiation. Wnt signalling components also play crucial roles in murine placental development controlling trophoblast lineage determination, chorioallantoic fusion and placental branching morphogenesis. However, the role of the pathway in human placentation, trophoblast development and differentiation is only partly understood. Here, we summarize our present knowledge about Wnt signalling in the human placenta and discuss its potential role in physiological and aberrant trophoblast invasion, gestational diseases and choriocarcinoma formation. Differentiation of proliferative first trimester cytotrophoblasts into invasive extravillous trophoblasts is associated with nuclear recruitment of β-catenin and induction of Wnt-dependent T-cell factor 4 suggesting that canonical Wnt signalling could be important for the formation and function of extravillous trophoblasts. Indeed, activation of the pathway was shown to promote trophoblast invasion in different in vitro trophoblast model systems as well as trophoblast cell fusion. Methylation-mediated silencing of inhibitors of Wnt signalling provided evidence for epigenetic activation of the pathway in placental tissues and choriocarcinoma cells. Similarly, abundant nuclear expression of β-catenin in invasive trophoblasts of complete hydatidiform moles suggested a role for hyper-activated Wnt signalling. In contrast, upregulation of Wnt inhibitors was noticed in placentae of women with preeclampsia, a disease characterized by shallow trophoblast invasion and incomplete spiral artery remodelling. Moreover, changes in Wnt signalling have been observed upon cytomegalovirus infection and in recurrent abortions. In summary, the current literature suggests a critical role of Wnt signalling in physiological and abnormal

Hedonic and incentive signals for body weight control.

Science.gov (United States)

Egecioglu, Emil; Skibicka, Karolina P; Hansson, Caroline; Alvarez-Crespo, Mayte; Friberg, P Anders; Jerlhag, Elisabet; Engel, Jörgen A; Dickson, Suzanne L

2011-09-01

Here we review the emerging neurobiological understanding of the role of the brain's reward system in the regulation of body weight in health and in disease. Common obesity is characterized by the over-consumption of palatable/rewarding foods, reflecting an imbalance in the relative importance of hedonic versus homeostatic signals. The popular 'incentive salience theory' of food reward recognises not only a hedonic/pleasure component ('liking') but also an incentive motivation component ('wanting' or 'reward-seeking'). Central to the neurobiology of the reward mechanism is the mesoaccumbal dopamine system that confers incentive motivation not only for natural rewards such as food but also by artificial rewards (eg. addictive drugs). Indeed, this mesoaccumbal dopamine system receives and integrates information about the incentive (rewarding) value of foods with information about metabolic status. Problematic over-eating likely reflects a changing balance in the control exerted by hypothalamic versus reward circuits and/or it could reflect an allostatic shift in the hedonic set point for food reward. Certainly, for obesity to prevail, metabolic satiety signals such as leptin and insulin fail to regain control of appetitive brain networks, including those involved in food reward. On the other hand, metabolic control could reflect increased signalling by the stomach-derived orexigenic hormone, ghrelin. We have shown that ghrelin activates the mesoaccumbal dopamine system and that central ghrelin signalling is required for reward from both chemical drugs (eg alcohol) and also from palatable food. Future therapies for problematic over-eating and obesity may include drugs that interfere with incentive motivation, such as ghrelin antagonists.

Control characteristics of cryogenic distillation column with a feedback stream for fusion reactor

International Nuclear Information System (INIS)

Yamanishi, Toshihiko; Okuno, Kenji

1997-01-01

The control characteristics of the cryogenic distillation column with a feedback stream have been discussed based on computer simulation results. This column plays an important role in fusion reactor. A new control system was proposed from the simulation results. The flow rate of top product is determined from the composition and flow rate of a main feed stream by a feedforward control loop. The flow rates of the feedback stream and vapor stream within the column are proportionally changed with a corresponding change of feed flow rate. The flow rate of vapor stream within the column is further adjusted to maintain product purity by a feedback control loop. The proposed system can control the product purity for a large fluctuation of feed composition, a change of feed flow rate, and an increase or decrease of the number of total theoretical stages of the column. The control system should be designed for each column by considering its operating conditions and function. The present study gives us a basic procedure for the design method of the control system of the cryogenic distillation column. (author)

Coordinated signal control for arterial intersections using fuzzy logic

Science.gov (United States)

Kermanian, Davood; Zare, Assef; Balochian, Saeed

2013-09-01

Every day growth of the vehicles has become one of the biggest problems of urbanism especially in major cities. This can waste people's time, increase the fuel consumption, air pollution, and increase the density of cars and vehicles. Fuzzy controllers have been widely used in many consumer products and industrial applications with success over the past two decades. This article proposes a comprehensive model of urban traffic network using state space equations and then using Fuzzy Logic Tool Box and SIMULINK Program MATLAB a fuzzy controller in order to optimize and coordinate signal control at two intersections at an arterial road. The fuzzy controller decides to extend, early cut or terminate a signal phase and phase sequence to ensure smooth flow of traffic with minimal waiting time and length of queue. Results show that the performance of the proposed traffic controller at novel fuzzy model is better that of conventional controllers under normal and abnormal traffic conditions.

Tools and methods for implementing the control systems on the Mirror Fusion Test Facility

International Nuclear Information System (INIS)

Minor, E.G.; Labiak, W.G.

1981-01-01

Installation of the major hardware subsystems for MFTF is nearing completion. These subsystems include the Fusion Chamber System, the eighty KV Neutral Beam System, the Superconducting Magnet System, and the Personnel Safety System. The Local Controls group has undertaken a uniform aproach to implementing the control systems for all of these hardware subsystems. This approach has two major aspects: (1) to provide a stand-alone computer control system with a remote, portable terminal so that computer control can be provided at the site of the hardware for initial testing, (2) to provide hardware simulators so that the complicated MFTF computer control system can be tested independent of the hardware. The software and hardware tools which were developed to carry out this plan will be described. Our experiences with bringing up subsystems containing up to 900 separate channels of control and status will also be described

Joint sparsity based heterogeneous data-level fusion for target detection and estimation

Science.gov (United States)

Niu, Ruixin; Zulch, Peter; Distasio, Marcello; Blasch, Erik; Shen, Dan; Chen, Genshe

2017-05-01

Typical surveillance systems employ decision- or feature-level fusion approaches to integrate heterogeneous sensor data, which are sub-optimal and incur information loss. In this paper, we investigate data-level heterogeneous sensor fusion. Since the sensors monitor the common targets of interest, whose states can be determined by only a few parameters, it is reasonable to assume that the measurement domain has a low intrinsic dimensionality. For heterogeneous sensor data, we develop a joint-sparse data-level fusion (JSDLF) approach based on the emerging joint sparse signal recovery techniques by discretizing the target state space. This approach is applied to fuse signals from multiple distributed radio frequency (RF) signal sensors and a video camera for joint target detection and state estimation. The JSDLF approach is data-driven and requires minimum prior information, since there is no need to know the time-varying RF signal amplitudes, or the image intensity of the targets. It can handle non-linearity in the sensor data due to state space discretization and the use of frequency/pixel selection matrices. Furthermore, for a multi-target case with J targets, the JSDLF approach only requires discretization in a single-target state space, instead of discretization in a J-target state space, as in the case of the generalized likelihood ratio test (GLRT) or the maximum likelihood estimator (MLE). Numerical examples are provided to demonstrate that the proposed JSDLF approach achieves excellent performance with near real-time accurate target position and velocity estimates.

The Signal Detection and Control Circuit Design for Confocal Auto-Focus System

OpenAIRE

Yin Liu; Jin Yu; Zeqiang Mo

2016-01-01

Based on the demands of Confocal Auto-Focus system, the implementation method of signal measurement circuit and control circuit is given. Using the high performance instrumental amplifier AD620BN, low noise precision FET Op amplifier AD795JRZ and ultralow offset voltage Op amplifier OP07EP, a signal measurement circuit used to converse the two differential light intensity signal to electric signal is designed. And a control circuit which takes MCU MSP430F149 as core processes the former signa...

Roentgenographic findings following anterior cervical fusion

Energy Technology Data Exchange (ETDEWEB)

Gore, D R; Gardner, G M; Sepic, S B; Murray, M P

1986-10-01

We reviewed the pre- and postoperative lateral cervical roentgenograms in 90 patients who had anterior fusions and compared their findings with age and sex-matched people without neck problems. The average interval from surgery to review was 5 years. Preoperatively, all patients had a higher incidence of degenerative spondylosis at the levels to be fused than their asymptomatic counterparts. Postoperatively, there was no difference in the incidence of degenerative change between the operated and the control group at the levels above and below the fusion with the exception of anterior osteophyte formation which was more frequent in those with fusions.

Thinking about the cold fusion fever

International Nuclear Information System (INIS)

Kitsunezaki, Akio

1989-01-01

The excitement since March 23 on cold fusion seems to be unprecedented evidence that the people of the world are waiting for fusion power with much enthusiasm. Cold fusion is really a surprise because it does not need high temperature and because it seems to be easy to enlarge the test tube into a useful power source if the claim by Professors Pons and Fleischmann at the University of Utah are true. The second announcement of cold fusion came from the Brigham Young University, also in the state of Utah, by Professor Jones, but his report was totally different from that given by Pons and Fleischmann. From the beginning of the 'fever', physicists have been very skeptical about cold fusion. Most of the critics and criticisms are targeted on Pons and Fleischmann rather than Jones, because not only was their paper poor but also their statements have not been scientific. They insisted that the heat came from fusion reaction, but without any scientific proof. They had not carried out the basic control experiment by running the same test with ordinary water instead of heavy water. A meeting on cold fusion was held at JAERI on May 15. At the end of the meeting, the some 260 attendants knew that cold fusion was not conceivable with the current scientific knowledge. (N.K.)

A centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage.

LENUS (Irish Health Repository)

2010-11-15

DNA damage can induce centrosome overduplication in a manner that requires G2-to-M checkpoint function, suggesting that genotoxic stress can decouple the centrosome and chromosome cycles. How this happens is unclear. Using live-cell imaging of cells that express fluorescently tagged NEDD1\\/GCP-WD and proliferating cell nuclear antigen, we found that ionizing radiation (IR)-induced centrosome amplification can occur outside S phase. Analysis of synchronized populations showed that significantly more centrosome amplification occurred after irradiation of G2-enriched populations compared with G1-enriched or asynchronous cells, consistent with G2 phase centrosome amplification. Irradiated and control populations of G2 cells were then fused to test whether centrosome overduplication is allowed through a diffusible stimulatory signal, or the loss of a duplication-inhibiting signal. Irradiated G2\\/irradiated G2 cell fusions showed significantly higher centrosome amplification levels than irradiated G2\\/unirradiated G2 fusions. Chicken-human cell fusions demonstrated that centrosome amplification was limited to the irradiated partner. Our finding that only the irradiated centrosome can duplicate supports a model where a centrosome-autonomous inhibitory signal is lost upon irradiation of G2 cells. We observed centriole disengagement after irradiation. Although overexpression of dominant-negative securin did not affect IR-induced centrosome amplification, Plk1 inhibition reduced radiation-induced amplification. Together, our data support centriole disengagement as a licensing signal for DNA damage-induced centrosome amplification.

2003 activity report of the development and research line in controlled thermonuclear fusion of the Plasma Associated Laboratory

International Nuclear Information System (INIS)

Ludwig, Gerson Otto

2004-01-01

This document represents the 2003 activity report of the development and research line in controlled thermonuclear fusion of the Plasma Associated Laboratory - Brazil, approaching the areas of toroidal systems for magnetic confinement, plasma heating, current generation and high temperature plasma diagnostic

FRIENDLY regulates mitochondrial distribution, fusion, and quality control in Arabidopsis.

Science.gov (United States)

El Zawily, Amr M; Schwarzländer, Markus; Finkemeier, Iris; Johnston, Iain G; Benamar, Abdelilah; Cao, Yongguo; Gissot, Clémence; Meyer, Andreas J; Wilson, Ken; Datla, Raju; Macherel, David; Jones, Nick S; Logan, David C

2014-10-01

Mitochondria are defining components of most eukaryotes. However, higher plant mitochondria differ biochemically, morphologically, and dynamically from those in other eukaryotes. FRIENDLY, a member of the CLUSTERED MITOCHONDRIA superfamily, is conserved among eukaryotes and is required for correct distribution of mitochondria within the cell. We sought to understand how disruption of FRIENDLY function in Arabidopsis (Arabidopsis thaliana) leads to mitochondrial clustering and the effects of this aberrant chondriome on cell and whole-plant physiology. We present evidence for a role of FRIENDLY in mediating intermitochondrial association, which is a necessary prelude to mitochondrial fusion. We demonstrate that disruption of mitochondrial association, motility, and chondriome structure in friendly affects mitochondrial quality control and leads to mitochondrial stress, cell death, and strong growth phenotypes. © 2014 American Society of Plant Biologists. All Rights Reserved.

Cell proliferation control by Notch signalling during imaginal discs development in Drosophila

Directory of Open Access Journals (Sweden)

Carlos Estella

2015-02-01

Full Text Available The Notch signalling pathway is evolutionary conserved and participates in numerous developmental processes, including the control of cell proliferation. However, Notch signalling can promote or restrain cell division depending on the developmental context, as has been observed in human cancer where Notch can function as a tumor suppressor or an oncogene. Thus, the outcome of Notch signalling can be influenced by the cross-talk between Notch and other signalling pathways. The use of model organisms such as Drosophila has been proven to be very valuable to understand the developmental role of the Notch pathway in different tissues and its relationship with other signalling pathways during cell proliferation control. Here we review recent studies in Drosophila that shed light in the developmental control of cell proliferation by the Notch pathway in different contexts such as the eye, wing and leg imaginal discs. We also discuss the autonomous and non-autonomous effects of the Notch pathway on cell proliferation and its interactions with different signalling pathways.

Rapid Elimination of the Persistent Synergid through a Cell Fusion Mechanism

KAUST Repository

Maruyama, Daisuke; Volz, Ronny; Takeuchi, Hidenori; Mori, Toshiyuki; Igawa, Tomoko; Kurihara, Daisuke; Kawashima, Tomokazu; Ueda, Minako; Ito, Masaki; Umeda, Masaaki; Nishikawa, Shuhichi; Groß -Hardt, Rita; Higashiyama, Tetsuya

2015-01-01

the endosperm proliferation, preventing attractions of excess number of pollen tubes (polytubey). The synergid-endosperm fusion is induced by fertilization of the central cell, while the egg cell fertilization predominantly activates ethylene signaling

Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.

Directory of Open Access Journals (Sweden)

Marc Liesa

Full Text Available There is no evidence to date on whether transcriptional regulators are able to shift the balance between mitochondrial fusion and fission events through selective control of gene expression.Here, we demonstrate that reduced mitochondrial size observed in knock-out mice for the transcriptional regulator PGC-1beta is associated with a selective reduction in Mitofusin 2 (Mfn2 expression, a mitochondrial fusion protein. This decrease in Mfn2 is specific since expression of the remaining components of mitochondrial fusion and fission machinery were not affected. Furthermore, PGC-1beta increases mitochondrial fusion and elongates mitochondrial tubules. This PGC-1beta-induced elongation specifically requires Mfn2 as this process is absent in Mfn2-ablated cells. Finally, we show that PGC-1beta increases Mfn2 promoter activity and transcription by coactivating the nuclear receptor Estrogen Related Receptor alpha (ERRalpha.Taken together, our data reveal a novel mechanism by which mammalian cells control mitochondrial fusion. In addition, we describe a novel role of PGC-1beta in mitochondrial physiology, namely the control of mitochondrial fusion mainly through Mfn2.

Thermoplastic fusion bonding using a pressure-assisted boiling point control system.

Science.gov (United States)

Park, Taehyun; Song, In-Hyouk; Park, Daniel S; You, Byoung Hee; Murphy, Michael C

2012-08-21

A novel thermoplastic fusion bonding method using a pressure-assisted boiling point (PABP) control system was developed to apply precise temperatures and pressures during bonding. Hot embossed polymethyl methacrylate (PMMA) components containing microchannels were sealed using the PABP system. Very low aspect ratio structures (AR = 1/100, 10 μm in depth and 1000 μm in width) were successfully sealed without collapse or deformation. The integrity and strength of the bonds on the sealed PMMA devices were evaluated using leakage and rupture tests; no leaks were detected and failure during the rupture tests occurred at pressures greater than 496 kPa. The PABP system was used to seal 3D shaped flexible PMMA devices successfully.

Muon nuclear fusion and low temperature nuclear fusion

International Nuclear Information System (INIS)

Nagamine, Kanetada

1990-01-01

Low temperature (or normal temperature) nuclear fusion is one of the phenomena causing nuclear fusion without requiring high temperature. In thermal nuclear fusion, the Coulomb barrier is overcome with the help of thermal energy, but in the low temperature nuclear fusion, the Coulomb barrier is neutralized by the introduction of the particles having larger mass than electrons and negative charges, at this time, if two nuclei can approach to the distance of 10 -13 cm in the neutral state, the occurrence of nuclear fusion reaction is expected. As the mass of the particles is heavier, the neutral region is smaller, and nuclear fusion is easy to occur. The particles to meet this purpose are the electrons within substances and muons. The research on muon nuclear fusion became suddenly active in the latter half of 1970s, the cause of which was the discovery of the fact that the formation of muons occurs resonantly rapidly in D-T and D-D systems. Muons are the unstable elementary particles having the life of 2.2 μs, and they can have positive and negative charges. In the muon catalyzed fusion, the muons with negative charge take part. The principle of the muon catalyzed fusion, its present status and future perspective, and the present status of low temperature nuclear fusion are reported. (K.I.)

Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum.

Science.gov (United States)

Sutton, Laurie P; Ostrovskaya, Olga; Dao, Maria; Xie, Keqiang; Orlandi, Cesare; Smith, Roy; Wee, Sunmee; Martemyanov, Kirill A

2016-08-01

Morphine mediates its euphoric and analgesic effects by acting on the μ-opioid receptor (MOR). MOR belongs to the family of G-protein coupled receptors whose signaling efficiency is controlled by the regulator of G-protein signaling (RGS) proteins. Our understanding of the molecular diversity of RGS proteins that control MOR signaling, their circuit specific actions, and underlying cellular mechanisms is very limited. We used genetic approaches to ablate regulator of G-protein signaling 7 (RGS7) both globally and in specific neuronal populations. We used conditioned place preference and self-administration paradigms to examine reward-related behavior and a battery of tests to assess analgesia, tolerance, and physical dependence to morphine. Electrophysiology approaches were applied to investigate the impact of RGS7 on morphine-induced alterations in neuronal excitability and plasticity of glutamatergic synapses. At least three animals were used for each assessment. Elimination of RGS7 enhanced reward, increased analgesia, delayed tolerance, and heightened withdrawal in response to morphine administration. RGS7 in striatal neurons was selectively responsible for determining the sensitivity of rewarding and reinforcing behaviors to morphine without affecting analgesia, tolerance, and withdrawal. In contrast, deletion of RGS7 in dopaminergic neurons did not influence morphine reward. RGS7 exerted its effects by controlling morphine-induced changes in excitability of medium spiny neurons in nucleus accumbens and gating the compositional plasticity of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid and N-methyl-D-aspartate receptors. This study identifies RGS7 as a novel regulator of MOR signaling by dissecting its circuit specific actions and pinpointing its role in regulating morphine reward by controlling the activity of nucleus accumbens neurons. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

High-energy fusion: A quest for a simple, small and environmentally acceptable colliding-beam fusion power source

International Nuclear Information System (INIS)

Maglich, B.

1978-01-01

Fusion goals should be lowered for a speedier research and development of a less ambitious but a workable 'low-gain fusion power amplifier', based on proven technologies and concepts. The aim of the Migma Program of Controlled Fusion is a small (10-15 liters) fusion power source based on colliding beams instead of plasma or laser heating. Its scientific and technological 'philosophy' is radically different from that of the governmental fusion programs of the USA and USSR. Migmacell uses radiation-free fuels, ('advanced fuels'), rather than tritium. Economic projections show that such a smaller power cell can be econonomically competitive in spite of its low power gain, because it can be mass produced. Power stations could be made either large or small and the power transmission and distribution pattern in the nation would change. An interspersion of energy resources would result. Minifusion opens the possibility to smaller countries (and medium size institutions of large countries), for participation in fusion research; this resource of research talent is presently excluded from fusion by the high cost of the mainline governmental research (over $ 200 million for one experimental fusion device, as compared to $ 1 million for migmacell). The time-scale for obtaining experimental results is reduced from decades to years. Experimental accomplishments to date and the further research needed, are presented. (orig.) [de

Control of stochastic resonance in bistable systems by using periodic signals

International Nuclear Information System (INIS)

Min, Lin; Li-Min, Fang; Yong-Jun, Zheng

2009-01-01

According to the characteristic structure of double wells in bistable systems, this paper analyses stochastic fluctuations in the single potential well and probability transitions between the two potential wells and proposes a method of controlling stochastic resonance by using a periodic signal. Results of theoretical analysis and numerical simulation show that the phenomenon of stochastic resonance happens when the time scales of the periodic signal and the noise-induced probability transitions between the two potential wells achieve stochastic synchronization. By adding a bistable system with a controllable periodic signal, fluctuations in the single potential well can be effectively controlled, thus affecting the probability transitions between the two potential wells. In this way, an effective control can be achieved which allows one to either enhance or realize stochastic resonance

How much laser power can propagate through fusion plasma?

International Nuclear Information System (INIS)

Lushnikov, Pavel M; Rose, Harvey A

2006-01-01

Propagation of intense laser beams is crucial for inertial confinement fusion, which requires precise beam control to achieve the compression and heating necessary to ignite the fusion reaction. The National Ignition Facility (NIF), where fusion will be attempted, is now under construction. Control of intense beam propagation may be ruined by laser beam self-focusing. We have identified the maximum laser beam power that can propagate through fusion plasma without significant self-focusing and have found excellent agreement with recent experimental data. This maximum is determined by the collective forward stimulated Brillouin scattering instability which suggests a way to increase the maximum power by appropriate choice of plasma composition with implication for NIF designs. Our theory also leads to the prediction of anti-correlation between beam spray and backscatter and therefore raises the possibility of indirect control of backscatter through manipulation of plasma ionization state or acoustic damping. We find a simple expression for laser intensity at onset of enhanced beam angular divergence (beam spray)

Controlled fusion and plasma physics

International Nuclear Information System (INIS)

Bickerton, R.J.

1991-01-01

On JET results were presented on additional heating power, on a recently discovered regime of enhanced pellet performance (PEP), on low-density H-mode plasma confinement with hot ions, bounds on very high electric currents by material limiters, the first experiments on lower hybrid current drive, on the L-H transition threshold dependence on the direction of the gradient-B drift, and on alpha-particle physics issues. The TFTR presentations focused on transport. Particle loss ramifications of the toroidal Alfven eigenmodes were found to be small, while their threshold of excitation is lower than theoretically predicted. On DIII-D a scaling study of transport with gyroradius as the only variable was reported, with approximately Bohm scaling emerging; but the effective heat diffusivity scaling could not be established due to profile consistency effects. While beta-limit investigations with DIII-D generally confirm the ideal, MHD limit found by Troyon, evidence of a reduction of the accessible range for the internal inductance with the safety factor seems to favour current-density control in a steady-state D-T burner. Onset of strongly sheared poloidal rotation in a thin layer during the L-H mode transition was experimentally shown, while a new, so-called VH (''very high'') confinement mode was discovered by boronization of the wall. The JT-90 tokamak has recently been upgraded to JT-60-U. Presentations by the ASDEX team summarized the lack of agreement with theory of L-mode confinement. With TEXTOR, an improved mode (I-mode) of confinement was found by boronization. Finally, reviews are included on the status of impurity transport and helium removal in tokamaks, on stellarators, alternative magnetic confinement systems, inertial confinement, and non-fusion plasma physics. 2 tabs

Annual report of the Summit Members' Working Group on Controlled Thermonuclear Fusion (Fusin Working Group (FWG))

International Nuclear Information System (INIS)

1987-04-01

The Summit Members' Working Group on Controlled Thermonuclear Fusion [Fusion Working Group (FWG)] was established in 1983 in response to the Declaration of the Heads of State and Government at the Versailles Economic Summit meeting of 1982, and in response to the subsequent report of the Working Group in Technology, Growth and Employment (TGE) as endorsed at the Williamsburg Summit meeting, 1983. This document contains the complete written record of each of the three FWG meetings which include the minutes, lists of attendees, agendas, statements, and summary conclusions as well as the full reports of the Technical Working Party. In addition, there is a pertinent exchange of correspondence between FWG members on the role of the Technical Working Party and a requested background paper on the modalities associated with a possible future ETR project

An Adaptive Traffic Signal Control in a Connected Vehicle Environment: A Systematic Review

Directory of Open Access Journals (Sweden)

Peng Jing

2017-08-01

Full Text Available In the last few years, traffic congestion has become a growing concern due to increasing vehicle ownerships in urban areas. Intersections are one of the major bottlenecks that contribute to urban traffic congestion. Traditional traffic signal control systems cannot adjust the timing pattern depending on road traffic demand. This results in excessive delays for road users. Adaptive traffic signal control in a connected vehicle environment has shown a powerful ability to effectively alleviate urban traffic congestions to achieve desirable objectives (e.g., delay minimization. Connected vehicle technology, as an emerging technology, is a mobile data platform that enables the real-time data exchange among vehicles and between vehicles and infrastructure. Although several reviews about traffic signal control or connected vehicles have been written, a systemic review of adaptive traffic signal control in a connected vehicle environment has not been made. Twenty-six eligible studies searched from six databases constitute the review. A quality evaluation was established based on previous research instruments and applied to the current review. The purpose of this paper is to critically review the existing methods of adaptive traffic signal control in a connected vehicle environment and to compare the advantages or disadvantages of those methods. Further, a systematic framework on connected vehicle based adaptive traffic signal control is summarized to support the future research. Future research is needed to develop more efficient and generic adaptive traffic signal control methods in a connected vehicle environment.

Tritium management in fusion reactors

International Nuclear Information System (INIS)

Galloway, T.R.

1978-05-01

This is a review paper covering the key environmental and safety issues and how they have been handled in the various magnetic and inertial confinement concepts and reference designs. The issues treated include: tritium accident analyses, tritium process control, occupational safety, HTO formation rate from the gas-phase, disposal of tritium contaminated wastes, and environmental impact--each covering the Joint European Tokamak (J.E.T. experiment), Tokamak Fusion Test Reactor (TFTR), Russian T-20, The Next Step (TNS) designs by Westinghouse/ORNL and General Atomic/ANL, the ANL and ORNL EPR's, the G.A. Doublet Demonstration Reactor, the Italian Fintor-D and the ORNL Demo Studies. There are also the following full scale plant reference designs: UWMAK-III, LASL's Theta Pinch Reactor Design (RTPR), Mirror Fusion Reactor (MFR), Tandem Mirror Reactor (TMR), and the Mirror Hybrid Reactor (MHR). There are four laser device breakeven experiments, SHIVA-NOVA, LLL reference designs, ORNL Laser Fusion power plant, the German ''Saturn,'' and LLL's Laser Fusion EPR I and II

Optimization of the fission--fusion hybrid concept

International Nuclear Information System (INIS)

Saltmarsh, M.J.; Grimes, W.R.; Santoro, R.T.

1979-04-01

One of the potentially attractive applications of controlled thermonuclear fusion is the fission--fusion hybrid concept. In this report we examine the possible role of the hybrid as a fissile fuel producer. We parameterize the advantages of the concept in terms of the performance of the fusion device and the breeding blanket and discuss some of the more troublesome features of existing design studies. The analysis suggests that hybrids based on deuterium--tritium (D--T) fusion devices are unlikely to be economically attractive and that they present formidable blanket technology problems. We suggest an alternative approach based on a semicatalyzed deuterium--deuterium (D--D) fusion reactor and a molten salt blanket. This concept is shown to emphasize the desirable features of the hybrid, to have considerably greater economic potential, and to mitigate many of the disadvantages of D--T-based systems

Use of green fluorescent protein fusions to analyse the N- and C-terminal signal peptides of GPI-anchored cell wall proteins in Candida albicans.

Science.gov (United States)

Mao, Yuxin; Zhang, Zimei; Wong, Brian

2003-12-01

Glycophosphatidylinositol (GPI)-anchored proteins account for 26-35% of the Candida albicans cell wall. To understand the signals that regulate these proteins' cell surface localization, green fluorescent protein (GFP) was fused to the N- and C-termini of the C. albicans cell wall proteins (CWPs) Hwp1p, Als3p and Rbt5p. C. albicans expressing all three fusion proteins were fluorescent at the cell surface. GFP was released from membrane fractions by PI-PLC and from cell walls by beta-glucanase, which implied that GFP was GPI-anchored to the plasma membrane and then covalently attached to cell wall glucans. Twenty and 25 amino acids, respectively, from the N- and C-termini of Hwp1p were sufficient to target GFP to the cell surface. C-terminal substitutions that are permitted by the omega rules (G613D, G613N, G613S, G613A, G615S) did not interfere with GFP localization, whereas some non-permitted substitutions (G613E, G613Q, G613R, G613T and G615Q) caused GFP to accumulate in intracellular ER-like structures and others (G615C, G613N/G615C and G613D/G615C) did not. These results imply that (i) GFP fusions can be used to analyse the N- and C-terminal signal peptides of GPI-anchored CWPs, (ii) the omega amino acid in Hwp1p is G613, and (iii) C can function at the omega+2 position in C. albicans GPI-anchored proteins.

Nuclear fusion - Inexhaustible source of energy for tomorrow

International Nuclear Information System (INIS)

Leiser, M.; Demchenko, V.

1989-09-01

The purpose of this paper is to provide a general description of nuclear fusion as an energy option for the future and to clarify to some extent the various issues - scientific, technological, economic and environmental - which are likely to be relevant to controlled thermonuclear fusion. Section 1 describes the world energy problem and some advantages of nuclear fusion compared to other energy options. Sections 2 and 3 describe the fundamentals of fusion energy, plasma confinement, heating and technological aspects of fusion researches. Some plasma confinement schemes (tokamak, stellarator, inertial confinement fusion) are described. The main experimental results and parameter devices are cited to illustrate the state of the art as of 1989. Various engineering problems associated with reactor design, magnetic systems, materials, plasma purity, fueling, blankets, environment, economics and safety are discussed. A description of both bilateral and multilateral efforts in fusion research under the auspices of the IAEA is presented in Section 4. (author). 11 refs, 4 figs, 1 tab

Survey of tritium wastes and effluents in near-term fusion-research facilities

International Nuclear Information System (INIS)

Bickford, W.E.; Dingee, D.A.; Willingham, C.E.

1981-08-01

The use of tritium control technology in near-term research facilities has been studied for both the magnetic and inertial confinement fusion programs. This study focused on routine generation of tritium wastes and effluents, with little referene to accidents or facility decommissioning. This report serves as an independent review of the effectiveness of planned control technology and radiological hazards associated with operation. The facilities examined for the magnetic fusion program included Fusion Materials Irradiation Testing Facility (FMIT), Tritium Systems Test Assembly (TSTA), and Tokamak Fusion Test Reactor (TFTR) in the magnetic fusion program, while NOVA and Antares facilities were examined for the inertial confinement program

Optical fibres for fusion plasma diagnostics systems

International Nuclear Information System (INIS)

Brichard, B.

2005-01-01

The condition to achieve and maintain the ignition of a thermonuclear fusion plasma ignition calls for the construction of a large scale fusion reactor, namely ITER. This reactor is designed to deliver an average fusion power of 500 MW. The burning of fusion plasma at such high power level will release a tremendous amount of energy in the form of particle fluxes and ionising radiation. This energy release, primarily absorbed by the plasma facing components, can significantly degrade the performances of the plasma diagnostic equipment surrounding the machine. To ensure a correct operation of the Tokamak we need to develop highly radiation-resistance devices. In plasma diagnostic systems, optical fibre is viewed as a convenient tool to transport light from the plasma edge to the diagnostic area. Radiation affects the optical performances of the fibre mainly by the occurrence of radiation-induced absorption and luminescence. Both effects degrade the light signal used for plasma diagnostic. SCK-CEN is currently assessing radiation-resistant glasses for optical fibres and is developing the associated qualification procedure. The main objectives of this study were to increase the lifetime of optical components in high radiation background and to develop a radiation resistance optical fibre capable to operate in the radiation background of ITER

New concepts for controlled fusion reactor blanket design

International Nuclear Information System (INIS)

Conn, R.W.; Kulcinski, G.L.; Avci, H.; El-Maghrabi, M.

1975-01-01

Several new concepts for fusion reactor blanket design based on the idea of shifting, or tailoring, the neutron spectrum incident on the first structural wall are presented. The spectral shifter is a nonstructural element which can be made of graphite, silicon carbide, or three dimensionally woven carbon fibers (and containing other materials as appropriate) placed between the neutron source and the first structural wall. The softened neutron spectrum incident on the structural components leads to lower gas production and atom displacement rates than in more standard fusion blanket designs. In turn, this results in longer anticipated lifetimes for the structural materials and can significantly reduce radioactivity and afterheat levels. In addition, the neutron spectrum in the first structural wall can be made to approach the flux shape in fast breeder reactors. Such spectral softening means that existing radiation facilities may be more profitably used to provide relevant materials radiation damage data for the structural materials in these fusion blanket designs. This general class of blanket concepts are referred to as internal spectral shifter and energy converter, or ISSEC concepts. These specific design concepts fall into three main categories: ISSEC/EB concepts based on utilizing existing designs which breed tritium behind the first structural wall; ISSEC/IB concepts based on breeding tritium inside the first vacuum wall; and ISSEC/Bu concepts based on using boron, carbon, and perhaps, beryllium to obtain an energy multiplier and converter design that does not attempt to breed tritium or utilize lithium. The detailed analyses relate specifically to the nuclear performance of ISSEC systems and to a discussion of materials radiation damage problems in the structural material.(U.S.)

Color Multifocus Image Fusion Using Empirical Mode Decomposition

Directory of Open Access Journals (Sweden)

S. Savić

2013-11-01

Full Text Available In this paper, a recently proposed grayscale multifocus image fusion method based on the first level of Empirical Mode Decomposition (EMD has been extended to color images. In addition, this paper deals with low contrast multifocus image fusion. The major advantages of the proposed methods are simplicity, absence of artifacts and control of contrast, while this isn’t the case with other pyramidal multifocus fusion methods. The efficiency of the proposed method is tested subjectively and with a vector gradient based objective measure, that is proposed in this paper for multifocus color image fusion. Subjective analysis performed on a multifocus image dataset has shown its superiority to the existing EMD and DWT based methods. The objective measures of grayscale and color image fusion show significantly better scores for this method than for the classic complex EMD fusion method.

Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling.

Science.gov (United States)

Wang, Ying; Branicky, Robyn; Noë, Alycia; Hekimi, Siegfried

2018-04-18

Superoxide dismutases (SODs) are universal enzymes of organisms that live in the presence of oxygen. They catalyze the conversion of superoxide into oxygen and hydrogen peroxide. Superoxide anions are the intended product of dedicated signaling enzymes as well as the byproduct of several metabolic processes including mitochondrial respiration. Through their activity, SOD enzymes control the levels of a variety of reactive oxygen species (ROS) and reactive nitrogen species, thus both limiting the potential toxicity of these molecules and controlling broad aspects of cellular life that are regulated by their signaling functions. All aerobic organisms have multiple SOD proteins targeted to different cellular and subcellular locations, reflecting the slow diffusion and multiple sources of their substrate superoxide. This compartmentalization also points to the need for fine local control of ROS signaling and to the possibility for ROS to signal between compartments. In this review, we discuss studies in model organisms and humans, which reveal the dual roles of SOD enzymes in controlling damage and regulating signaling. © 2018 Wang et al.

Challenges of nuclear fusion

International Nuclear Information System (INIS)

Kunkel, W.B.

1987-01-01

After 30 years of research and development in many countries, the magnetic confinement fusion experiments finally seem to be getting close to the original first goal: the point of ''scientific break-even''. Plans are being made for a generation of experiments and tests with actual controlled thermonuclear fusion conditions. Therefore engineers and material scientists are hard at work to develop the required technology. In this paper the principal elements of a generic fusion reactor are described briefly to introduce the reader to the nature of the problems at hand. The main portion of the presentation summarises the recent advances made in this field and discusses the major issues that still need to be addressed in regard to materials and technology for fusion power. Specific examples are the problems of the first wall and other components that come into direct contact with the plasma, where both lifetime and plasma contamination are matters of concern. Equally challenging are the demands on structural materials and on the magnetic-field coils, particularly in connection with the neutron-radiation environment of fusion reactors. Finally, the role of ceramics must be considered, both for insulators and for fuel breeding purposes. It is evident that we still have a formidable task before us, but at this point none of the problems seem to be insoluble. (author)

Fusion technology: The Iter fusion experiment

International Nuclear Information System (INIS)

Dietz, K.J.

1994-01-01

Plans for the Iter international fusion experiment, in which the European Union, Japan, Canada, Russia, Sweden, Switzerland, and the USA cooperate, were begun in 1985, and construction work started in early 1994. These activities serve for the preparation of the design and construction documents for a research reactor in which a stable fusion plasma is to be generated. This is to be the basis for the construction of a fusion reactor for electricity generation. Preparatory work was performed in the Tokamak experiments with JET and TFTR. The fusion power of 1.5 GW will be attained, thus enabling Iter to keep a deuterium-tritium plasma burning. (orig.) [de

Fusion fuel cycle: material requirements and potential effluents

International Nuclear Information System (INIS)

Teofilo, V.L.; Bickford, W.E.; Long, L.W.; Price, B.A.; Mellinger, P.J.; Willingham, C.E.; Young, J.K.

1980-10-01

Environmental effluents that may be associated with the fusion fuel cycle are identified. Existing standards for controlling their release are summarized and anticipated regulatory changes are identified. The ability of existing and planned environmental control technology to limit effluent releases to acceptable levels is evaluated. Reference tokamak fusion system concepts are described and the principal materials required of the associated fuel cycle are analyzed. These materials include the fusion fuels deuterium and tritium; helium, which is used as a coolant for both the blanket and superconducting magnets; lithium and beryllium used in the blanket; and niobium used in the magnets. The chemical and physical processes used to prepare these materials are also described

Fusion fuel cycle: material requirements and potential effluents

Energy Technology Data Exchange (ETDEWEB)

Teofilo, V.L.; Bickford, W.E.; Long, L.W.; Price, B.A.; Mellinger, P.J.; Willingham, C.E.; Young, J.K.

1980-10-01

Environmental effluents that may be associated with the fusion fuel cycle are identified. Existing standards for controlling their release are summarized and anticipated regulatory changes are identified. The ability of existing and planned environmental control technology to limit effluent releases to acceptable levels is evaluated. Reference tokamak fusion system concepts are described and the principal materials required of the associated fuel cycle are analyzed. These materials include the fusion fuels deuterium and tritium; helium, which is used as a coolant for both the blanket and superconducting magnets; lithium and beryllium used in the blanket; and niobium used in the magnets. The chemical and physical processes used to prepare these materials are also described.

49 CFR 236.205 - Signal control circuits; requirements.

Science.gov (United States)

2010-10-01

..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Automatic... car, (b) When points of a switch are not closed in proper position, (c) When an independently operated...

Conflicting views on the membrane fusion machinery and the fusion pore

DEFF Research Database (Denmark)

Sørensen, Jakob B

2009-01-01

of the assembly of the fusogenic SNARE-complex. Here, I review conflicting views on the function of the core fusion machinery consisting of the SNAREs, Munc18, complexin, and synaptotagmin. Munc18 controls docking of vesicles to the plasma membrane and initial SNARE-complex assembly, whereas complexin...

A review of signals used in sleep analysis

International Nuclear Information System (INIS)

Roebuck, A; Monasterio, V; Gederi, E; Osipov, M; Behar, J; Clifford, G D; Malhotra, A; Penzel, T

2014-01-01

This article presents a review of signals used for measuring physiology and activity during sleep and techniques for extracting information from these signals. We examine both clinical needs and biomedical signal processing approaches across a range of sensor types. Issues with recording and analysing the signals are discussed, together with their applicability to various clinical disorders. Both univariate and data fusion (exploiting the diverse characteristics of the primary recorded signals) approaches are discussed, together with a comparison of automated methods for analysing sleep. (topical review)

EURATOM strategy towards fusion energy

International Nuclear Information System (INIS)

Varandas, C.

2007-01-01

Research and development (Research and Development) activities in controlled thermonuclear fusion have been carried out since the 60's of the last century aiming at providing a new clean, powerful, practically inexhaustive, safe, environmentally friend and economically attractive energy source for the sustainable development of our society.The EURATOM Fusion Programme (EFP) has the leadership of the magnetic confinement Research and Development activities due to the excellent results obtained on JET and other specialized devices, such as ASDEX-Upgrade, TORE SUPRA, FTU, TCV, TEXTOR, CASTOR, ISTTOK, MAST, TJ-II, W7-X, RFX and EXTRAP. JET is the largest tokamak in operation and the single device that can use deuterium and tritium mixes. It has produced 16 MW of fusion power, during 3 seconds, with an energy amplification of 0.6. The next steps of the EFP strategy towards fusion energy are ITER complemented by a vigorous Accompanying Programme, DEMO and a prototype of a fusion power plant. ITER, the first experimental fusion reactor, is a large-scale project (35-year duration, 10000 MEuros budget), developed in the frame of a very broad international collaboration, involving EURATOM, Japan, Russia Federation, United States of America, Korea, China and India. ITER has two main objectives: (i) to prove the scientific and technical viability of fusion energy by producing 500 MW, during 300 seconds and a energy amplification between 10 and 20; and (ii) to test the simultaneous and integrated operation of the technologies needed for a fusion reactor. The Accompanying Programme aims to prepare the ITER scientific exploitation and the DEMO design, including the development of the International Fusion Materials Irradiation Facility (IFMIF). A substantial part of this programme will be carried out in the frame of the Broader Approach, an agreement signed by EURATOM and Japan. The main goal of DEMO is to produce electricity, during a long time, from nuclear fusion reactions. The

EMG Versus Torque Control of Human-Machine Systems: Equalizing Control Signal Variability Does not Equalize Error or Uncertainty.

Science.gov (United States)

Johnson, Reva E; Kording, Konrad P; Hargrove, Levi J; Sensinger, Jonathon W

2017-06-01

In this paper we asked the question: if we artificially raise the variability of torque control signals to match that of EMG, do subjects make similar errors and have similar uncertainty about their movements? We answered this question using two experiments in which subjects used three different control signals: torque, torque+noise, and EMG. First, we measured error on a simple target-hitting task in which subjects received visual feedback only at the end of their movements. We found that even when the signal-to-noise ratio was equal across EMG and torque+noise control signals, EMG resulted in larger errors. Second, we quantified uncertainty by measuring the just-noticeable difference of a visual perturbation. We found that for equal errors, EMG resulted in higher movement uncertainty than both torque and torque+noise. The differences suggest that performance and confidence are influenced by more than just the noisiness of the control signal, and suggest that other factors, such as the user's ability to incorporate feedback and develop accurate internal models, also have significant impacts on the performance and confidence of a person's actions. We theorize that users have difficulty distinguishing between random and systematic errors for EMG control, and future work should examine in more detail the types of errors made with EMG control.

Fluorescent protein pair emit intracellular FRET signal suitable for FACS screening

International Nuclear Information System (INIS)

Johansson, Daniel X.; Brismar, Hjalmar; Persson, Mats A.A.

2007-01-01

The fluorescent proteins ECFP and HcRed were shown to give an easily resolved FRET-signal when expressed as a fusion inside mammalian cells. HeLa-tat cells expressing ECFP, pHcRed, or the fusion protein pHcRed-ECFP were analyzed by flow cytometry after excitation of ECFP. Cells expressing HcRed-ECFP, or ECFP and HcRed, were mixed and FACS-sorted for FRET positive cells: HcRed-ECFP cells were greatly enriched (72 times). Next, cloned human antibodies were fused with ECFP and expressed anchored to the ER membrane. Their cognate antigens (HIV-1 gp120 or gp41) were fused to HcRed and co-expressed in the ER. An increase of 13.5 ± 1.5% (mean ± SEM) and 8.0 ± 0.7% in ECFP fluorescence for the specific antibodies reacting with gp120 or gp41, respectively, was noted after photobleaching. A positive control (HcRed-ECFP) gave a 14.8 ± 2.6% increase. Surprisingly, the unspecific antibody (anti-TT) showed 12.1 ± 1.1% increase, possibly because overexpression in the limited ER compartment gave false FRET signals

Adaptive Traffic Signal Control: Deep Reinforcement Learning Algorithm with Experience Replay and Target Network

OpenAIRE

Gao, Juntao; Shen, Yulong; Liu, Jia; Ito, Minoru; Shiratori, Norio

2017-01-01

Adaptive traffic signal control, which adjusts traffic signal timing according to real-time traffic, has been shown to be an effective method to reduce traffic congestion. Available works on adaptive traffic signal control make responsive traffic signal control decisions based on human-crafted features (e.g. vehicle queue length). However, human-crafted features are abstractions of raw traffic data (e.g., position and speed of vehicles), which ignore some useful traffic information and lead t...

Comparison of two different high performance mixed signal controllers for DC/DC converters

DEFF Research Database (Denmark)

Jakobsen, Lars Tønnes; Andersen, Michael Andreas E.

2006-01-01

This paper describes how mixed signal controllers combining a cheap microcontroller with a simple analogue circuit can offer high performance digital control for DC/DC converters. Mixed signal controllers have the same versatility and performance as DSP based controllers. It is important to have...... an engineer experienced in microcontroller programming write the software algorithms to achieve optimal performance. Two mixed signal controller designs based on the same 8-bit microcontroller are compared both theoretically and experimentally. A 16-bit PID compensator with a sampling frequency of 200 k......Hz implemented in the 16 MIPS, 8-bit ATTiny26 microcontroller is demonstrated....

Digital signal processing in power electronics control circuits

CERN Document Server

Sozanski, Krzysztof

2013-01-01

Many digital control circuits in current literature are described using analog transmittance. This may not always be acceptable, especially if the sampling frequency and power transistor switching frequencies are close to the band of interest. Therefore, a digital circuit is considered as a digital controller rather than an analog circuit. This helps to avoid errors and instability in high frequency components. Digital Signal Processing in Power Electronics Control Circuits covers problems concerning the design and realization of digital control algorithms for power electronics circuits using

Plasma nuclear fusion method

International Nuclear Information System (INIS)

Yamazaki, Shunpei; Miyanaga, Shoji; Wakaizumi, Kazuhiro; Takemura, Yasuhiko.

1990-01-01

Nuclear fusion reactions are attained by plasma gas phase reactions using magnetic fields and microwaves, and the degree of the reactions is controlled. That is, deuterium (D 2 ) is introduced into a plasma container by utilizing the resonance of microwaves capable of generating plasmas at high density higher by more than 10 - 10 3 times as compared with the high frequency and magnetic fields, and an electric energy is applied to convert gaseous D 2 into plasmas and nuclear fusion is conducted. Further, the deuterium ions in the plasmas are attracted to a surface of a material causing nuclear fusion under a negatively biased electric field from the outside (typically represented by Pd or Ti). Then, deuterium nuclei (d) or deuterium ions collide to the surface of the cathode on the side of palladium to conduct nuclear reaction at the surface or the inside (vicinity) thereof. However, a DC bias is applied as an external bias with the side of the palladium being negative. The cold nuclear fusion was demonstrated by placing a neutron counter in the vicinity of the container and confirming neutrons generated there. (I.S.)

Research programme on controlled thermonuclear fusion - Synthesis report 2010; Programme de recherche Fusion thermonucleaire controlee. Rapport de synthese 2010

Energy Technology Data Exchange (ETDEWEB)

Vaucher, C. [Secretariat d' Etat a l' education et a la recherche, Berne (Switzerland); Tran, M. Q.; Villard, L. [Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Marot, L. [University of Basel, Basel (Switzerland)

2011-07-01

Since 1978, research on thermonuclear fusion in Switzerland is closely related to the research programme of the European Atomic Energy Community (EURATOM). The Swiss projects tackle aspects of plasma physics and fusion technology. Switzerland participates to the construction and operation of the Joint European Torus (JET). The International Thermonuclear Experimental Reactor (ITER) is being built; the first plasma is expected in 2019. The 'Centre de Recherches en Physique des Plasmas' (CRPP) of the EPFL participates to EURATOM scientific and technological projects in magnetic confinement physics, through an experimental contribution (the Variable Configuration Tokamak, TCV) and theoretical studies. Thanks to the large flexibility of the TCV design and operation modus, plasmas of different shapes can be created and controlled, what is a very useful option to verify numerical simulation results. Besides, the injection of millimetre waves allows directing the injected power according to specific profiles. A configuration of type 'snowflakes' could be created, reducing the power deposition at the edge of the plasma. Theoretical studies on turbulence have improved the plasma stability in the TCV. For the first time in the world, TCV could reach a stable plasma, the plasma current being generated using the so-called 'bootstrap' phenomenon. Besides turbulence, studies were focused on heat and particle transport in tokamaks, on an analysis of the equilibrium and magneto-hydrodynamic stability of tokamaks and stellarators, on the application of radiofrequency waves and on the optimization of new confinement configurations. Experiments in the JET facility confirmed the numerical results of theoretical simulations. The TORPEX facility, which is simpler than TCV, allows high space-temporal resolution measurements for the study of turbulences and plasma threads ('blobs'). At the Paul Scherrer Institute (PSI), research topics include

A tethering complex drives the terminal stage of SNARE-dependent membrane fusion

Science.gov (United States)

D'Agostino, Massimo; Risselada, Herre Jelger; Lürick, Anna; Ungermann, Christian; Mayer, Andreas

2017-11-01

Membrane fusion in eukaryotic cells mediates the biogenesis of organelles, vesicular traffic between them, and exo- and endocytosis of important signalling molecules, such as hormones and neurotransmitters. Distinct tasks in intracellular membrane fusion have been assigned to conserved protein systems. Tethering proteins mediate the initial recognition and attachment of membranes, whereas SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein complexes are considered as the core fusion engine. SNARE complexes provide mechanical energy to distort membranes and drive them through a hemifusion intermediate towards the formation of a fusion pore. This last step is highly energy-demanding. Here we combine the in vivo and in vitro fusion of yeast vacuoles with molecular simulations to show that tethering proteins are critical for overcoming the final energy barrier to fusion pore formation. SNAREs alone drive vacuoles only into the hemifused state. Tethering proteins greatly increase the volume of SNARE complexes and deform the site of hemifusion, which lowers the energy barrier for pore opening and provides the driving force. Thereby, tethering proteins assume a crucial mechanical role in the terminal stage of membrane fusion that is likely to be conserved at multiple steps of vesicular traffic. We therefore propose that SNAREs and tethering proteins should be considered as a single, non-dissociable device that drives fusion. The core fusion machinery may then be larger and more complex than previously thought.

Measuring Workload Weak Resilience Signals at a Rail Control Post

NARCIS (Netherlands)

Siegel, A.W.; Schraagen, J.M.C.

2014-01-01

OCCUPATIONAL APPLICATIONS This article describes an observational study at a rail control post to measure workload weak resilience signals. A weak resilience signal indicates a possible degradation of a system's resilience, which is defined as the ability of a complex socio-technical system to cope

EMP Fusion

OpenAIRE

KUNTAY, Isık

2010-01-01

This paper introduces a novel fusion scheme, called EMP Fusion, which has the promise of achieving breakeven and realizing commercial fusion power. The method is based on harnessing the power of an electromagnetic pulse generated by the now well-developed flux compression technology. The electromagnetic pulse acts as a means of both heating up the plasma and confining the plasma, eliminating intermediate steps. The EMP Fusion device is simpler compared to other fusion devices and this reduces...

Identification of the feedforward component in manual control with predictable target signals.

Science.gov (United States)

Drop, Frank M; Pool, Daan M; Damveld, Herman J; van Paassen, Marinus M; Mulder, Max

2013-12-01

In the manual control of a dynamic system, the human controller (HC) often follows a visible and predictable reference path. Compared with a purely feedback control strategy, performance can be improved by making use of this knowledge of the reference. The operator could effectively introduce feedforward control in conjunction with a feedback path to compensate for errors, as hypothesized in literature. However, feedforward behavior has never been identified from experimental data, nor have the hypothesized models been validated. This paper investigates human control behavior in pursuit tracking of a predictable reference signal while being perturbed by a quasi-random multisine disturbance signal. An experiment was done in which the relative strength of the target and disturbance signals were systematically varied. The anticipated changes in control behavior were studied by means of an ARX model analysis and by fitting three parametric HC models: two different feedback models and a combined feedforward and feedback model. The ARX analysis shows that the experiment participants employed control action on both the error and the target signal. The control action on the target was similar to the inverse of the system dynamics. Model fits show that this behavior can be modeled best by the combined feedforward and feedback model.

Establishment of an Institute for Fusion Studies

International Nuclear Information System (INIS)

Hazeltine, R.D.

1992-07-01

The Institute for Fusion Studies is a national center for theoretical fusion plasma physics research. Its purposes are: (1) to conduct research on theoretical questions concerning the achievement of controlled fusion energy by means of magnetic confinement--including both fundamental problems of long-range significance, as well as shorter-term issues; (2) to serve as a center for information exchange, nationally and internationally, by hosting exchange visits, conferences, and workshops; (3) and to train students and postdoctoral research personnel for the fusion energy program and plasma physics research areas. The theoretical research results that are obtained by the Institute contribute mainly to the progress of national and international efforts in nuclear fusion research, whose goal is the development of fusion power.as a basic energy source. In addition to its primary focus on fusion physics, the Institute is also involved with research in related fields, such as advanced computing techniques, nonlinear dynamics, plasma astrophysics, and accelerator physics. The work of EFS scientists continued to receive national and international recognition. Numerous invited papers were given during the past year at workshops, conferences, and scientific meetings. Last year IFS scientists published 95 scientific articles in technical journals and monographs

Signal Propagation Delay as a Barrier to Control Applications in WAN

DEFF Research Database (Denmark)

Knudsen, Thomas Phillip; Patel, A.; Pedersen, Jens Myrup

With the advent in WAN of delay sensitive technical applications, such as remote control, signal propagation delay becomes a major problem. The extent of the problem is analysed by lower bounding the delay in relation to different transmission media. Requirements for reliability and bandwidth are...... are considered. The consequences of this bounding for communication network planning and provisioning are discussed in relation to mitigating the effects of signal propagation delay as a barrier to the penetration of control applications into WAN......With the advent in WAN of delay sensitive technical applications, such as remote control, signal propagation delay becomes a major problem. The extent of the problem is analysed by lower bounding the delay in relation to different transmission media. Requirements for reliability and bandwidth...

TORFA - toroidal reactor for fusion applications

International Nuclear Information System (INIS)

Jassby, D.L.

1980-09-01

The near-term goal of the US controlled fusion program should be the development, for practical applications, of an intense, quasi-steady, reliable 14-MeV neutron source with an electrical utilization efficiency at least 10 times larger than the value characterizing beam/solid-target neutron generators. This report outlines a method for implementing that goal, based on tokamak fusion reactors featuring resistive toroidal-field coils designed for ease of demountability

Fusion technology 1998

International Nuclear Information System (INIS)

Beaumont, B.; Libeyre, P.; Gentile, B. de; Tonon, G.

1998-01-01

The Symposium On Fusion Technology (SOFT) is held every two years with the objective to set the stage for the exchange of information on the design, construction and operation of fusion experiments and on the technology which is being developed for the next step devices and fusion reactors. By decision of the International Organizing Committee, the 20. SOFT includes invited talks, and oral and poster contributions in the following topics: plasma facing components, plasma heating and current drive, plasma engineering and control, experimental systems and diagnostics, magnets and power supplies, fuel technologies, remote operation, blanket and shield technologies, safety and environment, and system engineering and future devices. This symposium differs from the previous ones of this series by the way the present proceedings are produced. In order to have the written material available to the participants and the community at the nearest to the conference event, the papers have been collected 2 months in advance and printed in the present books. The goal was to deliver them to each participant upon arrival to the conference centre. These books contain all the papers corresponding to poster presentation, and the abstracts of the oral contributions and invited papers. The papers corresponding to these presentations, both oral and invited, will be published in 1999, after a standard review process, in a supplement of Fusion Engineering and Design. (author)

Improving Walkability Through Control Strategies at Signalized Intersections

Science.gov (United States)

2017-01-01

As cities and communities nationwide seek to develop Complete Streets that foster livability and accommodate all modes, signal timing control strategies that include pedestrians in the operational decision process are gaining importance. This researc...

Distributed control system for the FMIT

International Nuclear Information System (INIS)

Johnson, J.A.; Machen, D.R.; Suyama, R.M.

1979-01-01

The control system for the Fusion Materials Irradiation Test (FMIT) Facility will provide the primary data acquisition, control, and interface components that integrate all of the individual FMIT systems into a functional facility. The control system consists of a distributed computer network, control consoles and instrumentation subsystems. The FMIT Facility will be started, operated and secured from a Central Control Room. All FMIT systems and experimental functions will be monitored from the Central Control Room. The data acquisition and control signals will be handled by a data communications network, which connects dual computers in the Central Control Room to the microcomputers in CAMAC crates near the various subsystems of the facility

Verification of cold nuclear fusion reaction, (1)

International Nuclear Information System (INIS)

Yoshida, Zenko; Aratono, Yasuyuki; Hirabayashi, Takakuni

1991-01-01