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Sample records for control analysis mca

  1. Dual function of the McaS small RNA in controlling biofilm formation

    DEFF Research Database (Denmark)

    Jørgensen, Mikkel Girke; Thomason, Maureen K.; Havelund, Johannes;

    2013-01-01

    , and biofilm formation. Moreover, ectopic McaS expression leads to induction of two additional CsrA-repressed genes encoding diguanylate cyclases. Collectively, our study shows that McaS is a dual-function sRNA with roles in the two major post-transcriptional regulons controlled by the RNA-binding proteins Hfq...

  2. Development of the Taiwanese Mandarin Main Concept Analysis (TM-MCA: Normative and Preliminary Aphasic Data

    Directory of Open Access Journals (Sweden)

    Anthony Pak Hin Kong

    2014-03-01

    Full Text Available Introduction Compared to the English literature, there is a great paucity of studies focusing on quantitative analysis of aphasic oral discourse in Chinese, especially for native speakers of Taiwanese-Mandarin residing in Taiwan. Several studies that investigated deficits of aphasic discourse have been conducted in Cantonese Chinese, including the Cantonese Linguistic Communication Measure (CLCM, Kong & Law, 2004, Main Concept Analysis (MCA; Kong, 2009, and Cantonese version of the Quantitative Production Analysis (Law, 2001; Yiu & Worrall, 1996. Clinical or research application of these systems to the Taiwanese population is limited by the differences of phonology, semantics, and grammar between Taiwanese Mandarin and Cantonese. The current study, therefore, aimed to develop a culturally appropriate Taiwan Mandarin Main Concept Analysis (TM-MCA, by translating and adapting the MCA in Cantonese (Kong, 2009, 2011, and then to validate the tool on the basis of normal speakers and people with aphasia in Taiwan. Method Picture stimuli and main concepts for the TM-MCA: Eight certified Taiwanese SLPs participated and listed all main concepts upon presentation of the sequential pictures in Kong (2009. A main concept referred to a statement consisting of only one main verb with two or more pieces of essential information accurately related to the pictures and informative about the content. All main concepts mentioned by six out of eight SLPs were included in a preliminary main concept list. Further validation of the list involved recruiting eight normal speakers to orally describe the same picture sets. Only those scored as Accurate and Complete (AC or Accurate but Incomplete (AI by at least five speakers were put in the final list. Normative and aphasic data collection and analysis: Thirty six native Taiwanese Mandarin speakers and ten individuals with aphasia orally perform the same picture description tasks. Six measures, including Number of Accurate

  3. A Taiwanese Mandarin Main Concept Analysis (TM-MCA) for Quantification of Aphasic Oral Discourse

    Science.gov (United States)

    Kong, Anthony Pak-Hin; Yeh, Chun-Chih

    2015-01-01

    Background: Various quantitative systems have been proposed to examine aphasic oral narratives in English. A clinical tool for assessing discourse produced by Cantonese-speaking persons with aphasia (PWA), namely Main Concept Analysis (MCA), was developed recently for quantifying the presence, accuracy and completeness of a narrative. Similar…

  4. Performance analysis of gamma ray spectrometric parameters on digital signal and analog signal processing based MCA systems using NaI(Tl) detector

    Energy Technology Data Exchange (ETDEWEB)

    Kukreti, B.M., E-mail: bharatkuk@gmail.com [Atomic Minerals Directorate for Exploration and Research, Physics Laboratory, Department of Atomic Energy, Nongmynsong, AMD Complex, Shillong, Meghalaya 793019 (India); Sharma, G.K. [Atomic Minerals Directorate for Exploration and Research, Physics Laboratory, Department of Atomic Energy, Nongmynsong, AMD Complex, Shillong, Meghalaya 793019 (India)

    2012-05-15

    Accurate and speedy estimations of ppm range uranium and thorium in the geological and rock samples are most useful towards ongoing uranium investigations and identification of favorable radioactive zones in the exploration field areas. In this study with the existing 5 in. Multiplication-Sign 4 in. NaI(Tl) detector setup, prevailing background and time constraints, an enhanced geometrical setup has been worked out to improve the minimum detection limits for primordial radioelements K{sup 40}, U{sup 238} and Th{sup 232}. This geometrical setup has been integrated with the newly introduced, digital signal processing based MCA system for the routine spectrometric analysis of low concentration rock samples. Stability performance, during the long counting hours, for digital signal processing MCA system and its predecessor NIM bin based MCA system has been monitored, using the concept of statistical process control. Monitored results, over a time span of few months, have been quantified in terms of spectrometer's parameters such as Compton striping constants and Channel sensitivities, used for evaluating primordial radio element concentrations (K{sup 40}, U{sup 238} and Th{sup 232}) in geological samples. Results indicate stable dMCA performance, with a tendency of higher relative variance, about mean, particularly for Compton stripping constants. - Highlights: Black-Right-Pointing-Pointer Geometrical enhancement for ppm range primordial radio elemental determination. Black-Right-Pointing-Pointer Experimental constraints include detector setup, background and counting time. Black-Right-Pointing-Pointer Gamma spectrometric performance monitored on digital and analog MCA systems. Black-Right-Pointing-Pointer Study indicates higher variance of Compton stripping constants on digital MCA system.

  5. Use of multi-criteria analysis (MCA for supporting community forest management

    Directory of Open Access Journals (Sweden)

    Khadka C

    2012-04-01

    Full Text Available Sustainable forest management usually involves the use of criteria and indicators (C&I allowing the monitoring, reporting and assessment of management activities at national, regional and forest management unit levels. Experiences of such concepts are scarce in Nepal, particularly with regard to the evaluation of management activities within a Multi-Criteria Analysis (MCA framework. In this contribution we describe how a MCA approach can be used to efficiently exploit information, knowledge, and preferences of stakeholders to address community forest management problems. Beside rating and ranking techniques, the Analytic Hierarchy Process (AHP is used to examine the importance of six criteria and forty-four indicators in a sustainable forest management context with a broad range of stakeholder groups. An evaluation of four management strategies in the Shree Gyneshwar community forest user group allows to demonstrate the relevance of changing priorities for different criteria. A passive adaptive management strategy focusing on a multiple use of natural resources and the introduction of production-oriented measures were identified as the most preferable option. The results of this study show that the multi-criteria analysis approach, and in particular the AHP, can assist decision-makers in efficiently evaluating management problems and generating ideas for the long-term strategic planning process of community forest management, even under complex socio-economic and ecological conditions. In that context, compromise solutions enjoy a higher possibility of being successful, taking into account the different views of stakeholder groups.

  6. Project evaluation, sustainability and accountability: combining cost-benefit analysis (CBA) and multi-criteria analysis (MCA)

    OpenAIRE

    Sijtsma, F.J.

    2006-01-01

    General abstract Decision-makers in governments and businesses must choose among different project alternatives which, in varying degrees, contribute to sustainability. Decision-makers also have to account for their choices to a large audience or a broad range of stakeholders. This thesis is about the positive and negative aspects of using the main judgement-oriented evaluation tools of Cost-Benefit Analysis (CBA) and Multi Criteria Analysis (MCA) together in the context of sustainability and...

  7. Rapid and accurate identification of isolates of Candida species by melting peak and melting curve analysis of the internally transcribed spacer region 2 fragment (ITS2-MCA)

    NARCIS (Netherlands)

    Decat, E.; van Mechelen, E.; Saerens, B.; Vermeulen, S.J.T.; Boekhout, T.; de Blaiser, S.; Vaneechoutte, M.; Deschaght, P.

    2013-01-01

    Rapid identification of clinically important yeasts can facilitate the initiation of anti-fungal therapy, since susceptibility is largely species-dependent. We evaluated melting peak and melting curve analysis of the internally transcribed spacer region 2 fragment (ITS2-MCA) as an identification too

  8. Investigating changes in brain network properties in HIV-associated neurocognitive disease (HAND) using mutual connectivity analysis (MCA)

    Science.gov (United States)

    Abidin, Anas Zainul; D'Souza, Adora M.; Nagarajan, Mahesh B.; Wismüller, Axel

    2016-03-01

    About 50% of subjects infected with HIV present deficits in cognitive domains, which are known collectively as HIV associated neurocognitive disorder (HAND). The underlying synaptodendritic damage can be captured using resting state functional MRI, as has been demonstrated by a few earlier studies. Such damage may induce topological changes of brain connectivity networks. We test this hypothesis by capturing the functional interdependence of 90 brain network nodes using a Mutual Connectivity Analysis (MCA) framework with non-linear time series modeling based on Generalized Radial Basis function (GRBF) neural networks. The network nodes are selected based on the regions defined in the Automated Anatomic Labeling (AAL) atlas. Each node is represented by the average time series of the voxels of that region. The resulting networks are then characterized using graph-theoretic measures that quantify various network topology properties at a global as well as at a local level. We tested for differences in these properties in network graphs obtained for 10 subjects (6 male and 4 female, 5 HIV+ and 5 HIV-). Global network properties captured some differences between these subject cohorts, though significant differences were seen only with the clustering coefficient measure. Local network properties, such as local efficiency and the degree of connections, captured significant differences in regions of the frontal lobe, precentral and cingulate cortex amongst a few others. These results suggest that our method can be used to effectively capture differences occurring in brain network connectivity properties revealed by resting-state functional MRI in neurological disease states, such as HAND.

  9. NTS MC&A History

    Energy Technology Data Exchange (ETDEWEB)

    Mary Alice Price; Kim Young

    2008-07-01

    Within the past three and a half years, the Nevada Test Site (NTS) has progressed from a Category IV to a Category I nuclear material facility. In accordance with direction from the U.S. Department of Energy (DOE) Secretary and National Nuclear Security Administration (NNSA) Administrator, NTS received shipments of large quantities of special nuclear material from Los Alamos National Laboratory (LANL) and other sites in the DOE complex. December 2004 was the first occurrence of Category I material at the NTS, with the exception of two weeks of sub-critical underground testing in 2001, since 1992. The Material Control and Accountability (MC&A) program was originally a jointlab effort by LANL, Lawrence Livermore National Laboratory, and Bechtel Nevada, but in March 2006 the NNSA Nevada Site Office appointed the NTS Management and Operations contractor with sole responsibility. This paper will discuss the process and steps taken to transition the NTS MC&A program from multiple organizations to a single entity and from a Category IV to a Category I program. This transition flourished as MC&A progressed from the 2004 Office of Assessment (OA) rating of “Significant Weakness” to the 2007 OA assessment rating of “Effective Performance.” The paper will provide timelines, funding and staffing issues, OA assessment findings and corrective actions, and future expectations. The process has been challenging, but MC&A’s innovative responses to the challenges have been very successful.

  10. Mutual connectivity analysis (MCA) using generalized radial basis function neural networks for nonlinear functional connectivity network recovery in resting-state functional MRI

    Science.gov (United States)

    D'Souza, Adora M.; Abidin, Anas Zainul; Nagarajan, Mahesh B.; Wismüller, Axel

    2016-03-01

    We investigate the applicability of a computational framework, called mutual connectivity analysis (MCA), for directed functional connectivity analysis in both synthetic and resting-state functional MRI data. This framework comprises of first evaluating non-linear cross-predictability between every pair of time series prior to recovering the underlying network structure using community detection algorithms. We obtain the non-linear cross-prediction score between time series using Generalized Radial Basis Functions (GRBF) neural networks. These cross-prediction scores characterize the underlying functionally connected networks within the resting brain, which can be extracted using non-metric clustering approaches, such as the Louvain method. We first test our approach on synthetic models with known directional influence and network structure. Our method is able to capture the directional relationships between time series (with an area under the ROC curve = 0.92 +/- 0.037) as well as the underlying network structure (Rand index = 0.87 +/- 0.063) with high accuracy. Furthermore, we test this method for network recovery on resting-state fMRI data, where results are compared to the motor cortex network recovered from a motor stimulation sequence, resulting in a strong agreement between the two (Dice coefficient = 0.45). We conclude that our MCA approach is effective in analyzing non-linear directed functional connectivity and in revealing underlying functional network structure in complex systems.

  11. Metabolic control analysis of xylose catabolism in Aspergillus

    DEFF Research Database (Denmark)

    Prathumpai, Wai; Gabelgaard, J.B.; Wanchanthuek, P.;

    2003-01-01

    A kinetic model for xylose catabolism in Aspergillus is proposed. From a thermodynamic analysis it was found that the intermediate xylitol will accumulate during xylose catabolism. Use of the kinetic model allowed metabolic control analysis (MCA) of the xylose catabolic pathway to be carried out...... nidulans grown on media containing xylose, and a concentration up to 30 mM was found. Applying MCA showed that the first polyol dehydrogenase (XDH) in the catabolic pathway of xylose exerted the main flux control in the two strains of A. nidulans and A. niger NW324, but the flux control was exerted mainly...

  12. Metabolic control analysis of xylose catabolism in Aspergillus

    NARCIS (Netherlands)

    Prathumpai, W.; Gabelgaard, J.B.; Wanchanthuek, P.; Vondervoort, van de P.J.I.; Groot, de M.J.L.; McIntyre, M.; Nielsen, J.

    2003-01-01

    A kinetic model for xylose catabolism in Aspergillus is proposed. From a thermodynamic analysis it was found that the intermediate xylitol will accumulate during xylose catabolism. Use of the kinetic model allowed metabolic control analysis (MCA) of the xylose catabolic pathway to be carried out, an

  13. UCP3 Regulates Single-Channel Activity of the Cardiac mCa1.

    Science.gov (United States)

    Motloch, Lukas J; Gebing, Tina; Reda, Sara; Schwaiger, Astrid; Wolny, Martin; Hoppe, Uta C

    2016-08-01

    Mitochondrial Ca(2+) uptake (mCa(2+) uptake) is thought to be mediated by the mitochondrial Ca(2+) uniporter (MCU). UCP2 and UCP3 belong to a superfamily of mitochondrial ion transporters. Both proteins are expressed in the inner mitochondrial membrane of the heart. Recently, UCP2 was reported to modulate the function of the cardiac MCU related channel mCa1. However, the possible role of UCP3 in modulating cardiac mCa(2+) uptake via the MCU remains inconclusive. To understand the role of UCP3, we analyzed cardiac mCa1 single-channel activity in mitoplast-attached single-channel recordings from isolated murine cardiac mitoplasts, from adult wild-type controls (WT), and from UCP3 knockout mice (UCP3(-/-)). Single-channel registrations in UCP3(-/-) confirmed a murine voltage-gated Ca(2+) channel, i.e., mCa1, which was inhibited by Ru360. Compared to WT, mCa1 in UCP3(-/-) revealed similar single-channel characteristics. However, in UCP3(-/-) the channel exhibited decreased single-channel activity, which was insensitive to adenosine triphosphate (ATP) inhibition. Our results suggest that beyond UCP2, UCP3 also exhibits regulatory effects on cardiac mCa1/MCU function. Furthermore, we speculate that UCP3 might modulate previously described inhibitory effects of ATP on mCa1/MCU activity as well.

  14. Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Hideki Shigematsu

    Full Text Available Mechanosensing in plants is thought to be governed by sensory complexes containing a Ca²⁺-permeable, mechanosensitive channel. The plasma membrane protein MCA1 and its paralog MCA2 from Arabidopsis thaliana are involved in mechanical stress-induced Ca²⁺ influx and are thus considered as candidates for such channels or their regulators. Both MCA1 and MCA2 were functionally expressed in Sf9 cells using a baculovirus system in order to elucidate their molecular natures. Because of the abundance of protein in these cells, MCA2 was chosen for purification. Purified MCA2 in a detergent-solubilized state formed a tetramer, which was confirmed by chemical cross-linking. Single-particle analysis of cryo-electron microscope images was performed to depict the overall shape of the purified protein. The three-dimensional structure of MCA2 was reconstructed at a resolution of 26 Å from 5,500 particles and appears to comprise a small transmembrane region and large cytoplasmic region.

  15. Estimating the robustness of composite CBA & MCA assessments by variation of criteria importance order

    DEFF Research Database (Denmark)

    Jensen, Anders Vestergaard; Barfod, Michael Bruhn; Leleur, Steen

    This paper discusses the concept of using rank variation concerning the stake-holder prioritising of importance criteria for exploring the sensitivity of criteria weights in multi-criteria analysis (MCA). Thereby the robustness of the MCA-based decision support can be tested. The analysis described...... is based on the fact that when using MCA as a decision-support tool, questions often arise about the weighting (or prioritising) of the included criteria. This part of the MCA is seen as the most subjective part and could give reasons for discussion among the decision makers or stakeholders. Furthermore......, the relative weights can make a large difference in the resulting assessment of alternatives [1]. Therefore it is highly relevant to introduce a procedure for estimating the importance of criteria weights. This paper proposes a methodology for estimating the robustness of weights used in additive utility...

  16. Band-to-band registration and ortho-rectification of multilens/multispectral imagery: A case study of MiniMCA-12 acquired by a fixed-wing UAS

    Science.gov (United States)

    Jhan, Jyun-Ping; Rau, Jiann-Yeou; Huang, Cho-Ying

    2016-04-01

    MiniMCA (Miniature Multiple Camera Array) is a lightweight, frame-based, and multilens composed multispectral sensor, which is suitable to mount on an unmanned aerial systems (UAS) to acquire high spatial and temporal resolution imagery for various remote sensing applications. Since MiniMCA has significant band misregistration effect, an automatic and precise band-to-band registration (BBR) method is proposed in this study. Based on the principle of sensor plane-to-plane projection, a modified projective transformation (MPT) model is developed. It is to estimate all coefficients of MPT from indoor camera calibration, together with two systematic errors correction. Therefore, we can transfer all bands into the same image space. Quantitative error analysis shows that the proposed BBR scheme is scene independent and can achieve 0.33 pixels of accuracy, which demonstrating the proposed method is accurate and reliable. Meanwhile, it is difficult to mark ground control points (GCPs) on the MiniMCA images, as its spatial resolution is low when the flight height is higher than 400 m. In this study, a higher resolution RGB camera is adopted to produce digital surface model (DSM) and assist MiniMCA ortho-image generation. After precise BBR, only one reference band of MiniMCA image is necessary for aerial triangulation because all bands have same exterior and interior orientation parameters. It means that all the MiniMCA imagery can be ortho-rectified through the same exterior and interior orientation parameters of the reference band. The result of the proposed ortho-rectification procedure shows the co-registration errors between MiniMCA reference band and the RGB ortho-images is less than 0.6 pixels.

  17. Evaluating and prioritizing technologies for adaptation to climate change. A hands on guidance to multi criteria analysis (MCA) and the identification and assessment of related criteria

    DEFF Research Database (Denmark)

    Trærup, Sara Lærke Meltofte; Bakkegaard, Riyong Kim

    The objective of this guidance is to guide consultants, decision makers and technical experts on how to facilitate discussions for prioritizing adaptation technologies, and to support the stakeholders in identifying appropriate criteria for this analysis.......The objective of this guidance is to guide consultants, decision makers and technical experts on how to facilitate discussions for prioritizing adaptation technologies, and to support the stakeholders in identifying appropriate criteria for this analysis....

  18. A Simulation of Energy Storage System for Improving the Power System Stability with Grid-Connected PV using MCA Analysis and LabVIEW Tool

    Directory of Open Access Journals (Sweden)

    Jindrich Stuchly

    2015-01-01

    Full Text Available The large-scale penetration of distributed, Renewable power plants require transfers of large amounts of energy. This, in turn, puts a high strain on the energy delivery infrastructure. In particular, photovoltaic power plants supply energy with high intermittency, possibly affecting the stability of the grid by changing the voltage at the plant connection point. In this contribution, we summarize the main negative effects of selected and real-operated grid connected photovoltaic plant. Thereafter a review of suitable Energy storage systems to mitigate the negative effects has been carried out, compared and evaluated using Multi-criterion analysis. Based on this analysis, data collected at the plant and the grid, are used to design the energy storage systems to support connection of the plant to the grid. The cooperation of these systems is then analysed and evaluated using simulation tools created in LabVIEW for this purpose. The simulation results demonstrate the capability of energy storage system solutions to significantly reduce the negative feedback effects of Photovoltaic Power Plan to the low voltage grid.

  19. Cortical Reorganization of Language Functioning Following Perinatal Left MCA Stroke

    Science.gov (United States)

    Tillema, Jan-Mendelt; Byars, Anna W.; Jacola, Lisa M.; Schapiro, Mark B.; Schmithorst, Vince J.; Szaflarski, Jerzy P.; Holland, Scott K.

    2008-01-01

    Objective: Functional MRI was used to determine differences in patterns of cortical activation between children who suffered perinatal left middle cerebral artery (MCA) stroke and healthy children performing a silent verb generation task. Methods: Ten children with prior perinatal left MCA stroke (age 6-16 years) and ten healthy age matched…

  20. Status of Activities to Implement a Sustainable System of MC&A Equipment and Methodological Support at Rosatom Facilities

    Energy Technology Data Exchange (ETDEWEB)

    J.D. Sanders

    2010-07-01

    Under the U.S.-Russian Material Protection, Control and Accounting (MPC&A) Program, the Material Control and Accounting Measurements (MCAM) Project has supported a joint U.S.-Russian effort to coordinate improvements of the Russian MC&A measurement system. These efforts have resulted in the development of a MC&A Equipment and Methodological Support (MEMS) Strategic Plan (SP), developed by the Russian MEM Working Group. The MEMS SP covers implementation of MC&A measurement equipment, as well as the development, attestation and implementation of measurement methodologies and reference materials at the facility and industry levels. This paper provides an overview of the activities conducted under the MEMS SP, as well as a status on current efforts to develop reference materials, implement destructive and nondestructive assay measurement methodologies, and implement sample exchange, scrap and holdup measurement programs across Russian nuclear facilities.

  1. Body protein status in Fischer 344 rats bearing the MCA sarcoma

    Energy Technology Data Exchange (ETDEWEB)

    Radcliffe, J.D.

    1986-03-05

    The effect of a methylcholanthrene (MCA) sarcoma on the protein status of adult, male, Fischer-344 rats was investigated. Three groups of ten rats were used. One group (TB) was inoculated with MCA sarcoma tissue, control (C) and pair-fed (PF) groups received saline only. Rats were fed a purified (20% casein, 20% fat, 45% sucrose) diet from day 7 post-transplant, when tumors became palpable. Food intake of TB was depressed relative to C at day 15 PT. Animals were killed at day 22 PT. In comparison to C, tumor growth was associated with a decrease in gastrocnemius muscle protein content and an increase in spleen weight and protein content. There was no effect of tumor growth on the weight or protein content of liver, heart, or kidneys. Data from PF animals suggested that decreased gastrocnemius muscle protein content was partly attributable to decreased food intake and partly to tumor growth; the increased spleen protein was due to tumor growth per se. Thus, growth of the MCA sarcoma affects host protein status. Some of these effects are caused partly by hypophagia and partly by tumor growth and others are due to tumor growth per se.

  2. 32 CFR 644.417 - For MCA family housing.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true For MCA family housing. 644.417 Section 644.417... family housing. The Act of 1 September 1954, Pub. L. 765, 83rd Congress (68 Stat. 1119), as amended by... Construction-Army Family Housing at Military Installations and Facilities.”...

  3. MCA Based Performance Evaluation of Project Selection

    CERN Document Server

    Bakshi, Tuli

    2011-01-01

    Multi-criteria decision support systems are used in various fields of human activities. In every alternative multi-criteria decision making problem can be represented by a set of properties or constraints. The properties can be qualitative & quantitative. For measurement of these properties, there are different unit, as well as there are different optimization techniques. Depending upon the desired goal, the normalization aims for obtaining reference scales of values of these properties. This paper deals with a new additive ratio assessment method. In order to make the appropriate decision and to make a proper comparison among the available alternatives Analytic Hierarchy Process (AHP) and ARAS have been used. The uses of AHP is for analysis the structure of the project selection problem and to assign the weights of the properties and the ARAS method is used to obtain the final ranking and select the best one among the projects. To illustrate the above mention methods survey data on the expansion of optic...

  4. MCA Based Performance Evaluation of Project Selection

    Directory of Open Access Journals (Sweden)

    Tuli Bakshi

    2011-04-01

    Full Text Available Multi-criteria decision support systems are used in various fields of human activities. In every alternativemulti-criteria decision making problem can be represented by a set of properties or constraints. Theproperties can be qualitative & quantitative. For measurement of these properties, there are differentunit, as well as there are different optimization techniques. Depending upon the desired goal, thenormalization aims for obtaining reference scales of values of these properties. This paper deals with anew additive ratio assessment method. In order to make the appropriate decision and to make a propercomparison among the available alternatives Analytic Hierarchy Process (AHP and ARAS have beenused. The uses of AHP is for analysis the structure of the project selection problem and to assign theweights of the properties and the ARAS method is used to obtain the final ranking and select the best oneamong the projects. To illustrate the above mention methods survey data on the expansion of optical fibrefor a telecommunication sector is used. The decision maker can also used different weight combination inthe decision making process according to the demand of the system.

  5. Identity of cofactor bound to mycothiol conjugate amidase (Mca) influenced by expression and purification conditions.

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    Kocabas, Evren; Liu, Hualan; Hernick, Marcy

    2015-08-01

    Mycothiol serves as the primary reducing agent in Mycobacterium species, and is also a cofactor for the detoxification of xenobiotics. Mycothiol conjugate amidase (Mca) is a metalloamidase that catalyzes the cleavage of MS-conjugates to form a mercapturic acid, which is excreted from the mycobacterium, and 1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside. Herein we report on the metal cofactor preferences of Mca from Mycobacterium smegmatis and Mycobacterium tuberculosis. Importantly, results from homology models of Mca from M. smegmatis and M. tuberculosis suggest that the metal binding site of Mca is identical to that of the closely related protein N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB). This finding is supported by results from zinc ion affinity measurements that indicate Mca and MshB have comparable K(D)(ZnII) values (~10-20 pM). Furthermore, results from pull-down experiments using Halo-Mca indicate that Mca purifies with (stoichiometric) Fe(2+) when purified under anaerobic conditions, and Zn(2+) when purified under aerobic conditions. Consequently, Mca is likely a Fe(2+)-dependent enzyme under physiological conditions; with Zn(2+)-Mca an experimental artifact that could become biologically relevant under oxidatively stressed conditions. Importantly, these findings suggest that efforts towards the design of Mca inhibitors should include targeting the Fe(2+) form of the enzyme. PMID:26044118

  6. A 256 channel portable MCA for field application [Paper No.:I3

    International Nuclear Information System (INIS)

    In-situ gamma-spectrometry is a very important tool to characterise the contamination resulting due to radioactive fall out. Even in reactor environment this technique is helpful in analysing contaminations and the leakages on the spot. A battery powered 256 channel portable pulse height analyser has been developed to meet this requirement. The analyser consists of a single card Wilkinson type 8 bit ADC cum linear amplifier interfaced to an 8085 based micro computer. The MCA uses 2x2 inch NaI(Tl) detector and provides minimal necessary front panel controls for field use. A built-in DC to DC converter generates EHT for detector system and all the necessary DC voltages (+5V, ± 12V) from a 6V (7AH) battery. The MCA is capable of storing around 60 spectrums sequentially which can be down-loaded into a PC for further processing through built in serial RS-232 port. The paper describes the hardware and software developed for the system, and its performance evaluations. (author). 3 figs

  7. Real-time PCR/MCA assay using fluorescence resonance energy transfer for the genotyping of resistance related DHPS-540 mutations in Plasmodium falciparum

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    Dujardin Jean-Claude

    2008-03-01

    Full Text Available Abstract Background Sulphadoxine-pyrimethamine has been abandoned as first- or second-line treatment by most African malaria endemic countries in favour of artemisinin-based combination treatments, but the drug is still used as intermittent preventive treatment during pregnancy. However, resistance to sulphadoxine-pyrimethamine has been increasing in the past few years and, although the link between molecular markers and treatment failure has not been firmly established, at least for pregnant women, it is important to monitor such markers. Methods This paper reports a novel sensitive, semi-quantitative and specific real-time PCR and melting curve analysis (MCA assay using fluorescence resonance energy transfer (FRET for the detection of DHPS-540, an important predictor for SP resistance. FRET/MCA was evaluated using 78 clinical samples from malaria patients and compared to PCR-RFLP. Results Sixty-two samples were in perfect agreement between both assays. One sample showed a small wild type signal with FRET/MCA that indicates a polyclonal infection. Four samples were not able to generate enough material in both assays to distinguish mutant from wild-type infection, six samples gave no signal in PCR-RFLP and five samples gave no amplification in FRET/MCA. Conclusion FRET/MCA is an effective tool for the identification of SNPs in drug studies and epidemiological surveys on resistance markers in general and DHPS-540 mutation in particular.

  8. Treatment of middle cerebral artery (MCA) aneurysms: a review of the literature

    Institute of Scientific and Technical Information of China (English)

    Wuyang Yang; Judy Huang

    2015-01-01

    Microsurgical treatment is well established as the preferred strategy for definitive obliteration of middle cerebral artery (MCA) aneurysms.However, increasing reports on the feasibility and efficacy of endovascular treatment of MCA aneurysms in large case series suggest coiling as a viable alternative to microsurgery.This review provides a critical overview of the current literature regarding MCA aneurysm treatment, with the objective to clarify the available evidence of efficacy with microsurgical compared to endovascular treatment.

  9. Clip reconstruction of a large right MCA bifurcation aneurysm. Case report

    Directory of Open Access Journals (Sweden)

    Giovani A.

    2014-06-01

    Full Text Available We report a case of complex large middle cerebral artery (MCA bifurcation aneurysm that ruptured during dissection from the very adherent MCA branches but was successfully clipped and the MCA bifurcation reconstructed using 4 Yasargill clips. Through a right pterional craniotomy the sylvian fissure was largely opened as to allow enough workspace for clipping the aneurysm and placing a temporary clip on M1. The pacient recovered very well after surgery and was discharged after 1 week with no neurological deficit. Complex MCA bifurcation aneurysms can be safely reconstructed using regular clips, without the need of using fenestrated clips or complex by-pass procedures.

  10. MCaVoH: A toolkit for mining, classification and visualization of human microbiota.

    Science.gov (United States)

    Nisar, Maryum; Noureen, Nighat; Fazal, Sahar; Qadir, Muhammad Abdul

    2015-10-01

    Human body is the home for a large number of microbes. The complexity of enterotype depends on the body site. Microbial communities in various samples from different regions are being classified on the basis of 16S rRNA gene sequences. With the improvement in sequencing technologies various computational methods have been used for the analysis of microbiome data. Despite several available machine learning techniques there is no single platform available which could provide several techniques for clustering, multiclass classification, comparative analysis and the most significantly the identification of the subgroups present within larger groups of human microbial communities. We present a tool named MCaVoH for this purpose which performs clustering and classification of 16S rRNA sequence data and highlight various groups. Our tool has an added facility of biclustering which produces local group of communities present within larger groups (clusters). The core objective of our work was to identify the interaction between various bacterial species along with monitoring the composition and variations in microbial communities. MCaVoH also evaluates the performance and efficiency of different techniques using comparative analysis. The results are visualized through different plots and graphs. We implemented our tool in MATLAB. We tested our tool on several real and simulated 16S rRNA data sets and it outperforms several existing methods. Our tool provides a single platform for using multiple clustering, classification algorithms, local community identification along with their comparison which has not been done so far. Tool is available at https://sourceforge.net/projects/mcavoh/. PMID:26193336

  11. Collapse of the western North America climate dipole during the MCA and LIA

    Science.gov (United States)

    Asmerom, Y.; Polyak, V. J.; Rasmussen, J.; Burns, S. J.; Lachniet, M. S.

    2011-12-01

    Understanding of the teleconnections between regional climate regimes and the time-scale of the stability of these teleconnections is crucial for building predictive models of climate change. Using annually-resolved speleothem physical (band thickness, hiatus and mineralogy) and oxygen and carbon isotopic effective moisture proxy data, we show climate variability in the southwestern United States (SW) during the critical Medieval Climate Anomaly and Little Ice Age (LIA) intervals. Although the MCA overall was not markedly drier than the wet latter half of the LIA, it was punctuated by multiple megadroughts. The driest interval was the early LIA, during which we identify an extended multi-century drought, which we will refer to as a Super Drought (SD), occurring during the early LIA ca. AD 1350 to AD 1650. There is a well-established dipole response to Pacific Decadal Oscillation (PDO) and El Nino-Southern Oscillation (ENSO) variability between the SW and northwestern United States (NW), and the SW and the Asian monsoon during the modern and overall Holocene climate regime. Our data indicate that this climate dipole apparently collapsed during the MCA-LIA, extending back to about 300 AD, such that pluvial and drought intervals in the SW and NW, and SW and Asian monsoon occur contemporaneously over this period. The modern positive relationship between moisture and the PDO observed in the SW is also reversed. During this interval the PDO is negatively correlated with SW moisture amount. In addition, the strong solar control of Holocene climate observed previously in western North America and the Asian monsoon is weakened during parts of this interval, such that solar maxima and minima do not correlate coherently with precipitation variability both in North America and the Asian monsoon. The MCA-early LIA period in which the megadroughts dominate occurs within the prominently positive phase of the North Atlantic Oscillation (NAO). One potential mechanism of propagating

  12. A reliable approach to distinguish between transient with and without HFOs using TQWT and MCA.

    Science.gov (United States)

    Chaibi, Sahbi; Lajnef, Tarek; Sakka, Zied; Samet, Mounir; Kachouri, Abdennaceur

    2014-07-30

    Recent studies have reported that discrete high frequency oscillations (HFOs) in the range of 80-500Hz may serve as promising biomarkers of the seizure focus in humans. Visual scoring of HFOs is tiring, time consuming, highly subjective and requires a great deal of mental concentration. Due to the recent explosion of HFOs research, development of a robust automated detector is expected to play a vital role in studying HFOs and their relationship to epileptogenesis. Therefore, a handful of automated detectors have been introduced in the literature over the past few years. In fact, all the proposed methods have been associated with high false-positive rates, which essentially arising from filtered sharp transients like spikes, sharp waves and artifacts. In order to specifically minimize false positive rates and improve the specificity of HFOs detection, we proposed a new approach, which is a combination of tunable Q-factor wavelet transform (TQWT), morphological component analysis (MCA) and complex Morlet wavelet (CMW). The main findings of this study can be summarized as follows: The proposed method results in a sensitivity of 96.77%, a specificity of 85.00% and a false discovery rate (FDR) of 07.41%. Compared to this, the classical CMW method applied directly on the signals without pre-processing by TQWT-MCA achieves a sensitivity of 98.71%, a specificity of 18.75%, and an FDR of 29.95%. The proposed method may be considered highly accurate to distinguish between transients with and without HFOs. Consequently, it is remarkably reliable and robust for the detection of HFOs.

  13. In-house development of an FPGA-based MCA8K for gamma-ray spectrometer.

    Science.gov (United States)

    Lanh, Dang; Son, Pham Ngoc; Son, Nguyen An

    2014-01-01

    The objective of this work is domestic development of electronics instruments. It used for measuring ionization radiation and practical training at Nuclear Research Institute (NRI), Dalat, Vietnam. The aim of this work is to study and develop a novel MCA8k for Gamma-ray spectrometer concerning experimental nuclear physics. An approach for design and construction of the aforementioned instrument is to apply logic integrating techniques via Field Programmable Gate Arrays (FPGA) under Max + PlusII, Altera. The instrument allows interfacing to PC with self-developed application software. Scientific significance of this work is partly to contribute to opening a research direction in the field of nuclear electronics science for design and construction of radiation measurement instruments with the advanced IC technology in Vietnam. Practical significance of this work is partly to contribute to enhancement of capabilities in developing radiation measurement instruments for experimental research as well as practical training in nuclear physics. The advantages of FPGA: overcoming ballistic deficit, decrement of serial and parallel noise, flexible in programming, control of the system by software without an interfere of hardware. The disadvantages of FPGA: requirement of good knowledge of VHDL and professional tools for development of a expected project. A new electronics module of MCA8k has been achieved. Some main results obtained from the experimental testing are as follows: differential nonlinearity (DNL) of FPGA-MCA8k approximately 1.27%, integral nonlinearity (INL) = 0.607%, time conversion ≈ 2.2 μs, deadtime (DT) is 0.75%. Data Acquisition Program MCANRI written in VC (+ +)6.0, self-executed under Windows XP environment.

  14. Hydrographic changes in the subpolar North Atlantic at the MCA to LIA transition

    Science.gov (United States)

    Divine, Dmitry; Miettinen, Arto; Husum, Katrine; Koc, Nalan

    2016-04-01

    A network of four marine sediment cores from the northern North Atlantic is used to study hydrographic changes in surface water masses during the last 2000 years with a special focus on the Medieval Climate Anomaly (MCA) to the Little Ice Age (LIA) transition. Three of the cores are recovered from the sites located on main pathways of warm Atlantic water to the Arctic: M95-2011 (Vøring plateau, Norwegian Sea), Rapid-21 COM and LO-14 (Reykjanes Ridge, south of Iceland). The fourth core MD99-2322 is from the SE Greenland shelf (Denmark Strait), and it is influenced by the cold water outflow from the Arctic. The cores were analyzed continuously for planktonic diatoms with a high decadal to subdecadal temporal resolution. Past changes in the spatial distribution of surface water masses have been studied identifying factors, or typical species compositions, in downcore diatom assemblages. To derive the factors a Q-mode factor analysis has been applied to the extended modern calibration data set of 184 surface sediment samples from the North Atlantic, the Labrador Sea, the Nordic Seas, and Baffin Bay. SSTs have also been reconstructed using transfer functions. Variations of the reconstructed SSTs and loadings of major contributing factors reveal a complex regional pattern of changes in the structure of circulation during the MCA/LIA transition (1200-1400 AD). In the Norwegian Sea, the factors associated with assemblages typical for warmer and saline North Atlantic waters are partly displaced by colder and fresher water dwelling diatoms suggesting an eastward migration of mixed Arctic/Atlantic water masses into the Norwegian Sea. The two cores south of Iceland show a westward propagation of a warm water pulse as evidenced by the dominance of assemblages, which today are typical for the waters ca 5° further south than the current study sites. At the SE Greenland shelf an abrupt shift (ca. 50 years) in factors associated with different sea ice zone dwelling diatoms

  15. Construction of a reasonable multi channel analyzer (MCA) with an educational FPGA board

    International Nuclear Information System (INIS)

    In resent years, the performances of new electronic devices, for example FPGA or so on, have been improved, and these devices become more cost-effective ones year by year. Moreover, prices of personal computers have become less expensive, and the programming environment on PC becomes much user-friendly and easy to operate in this decimal year. These advancements have possibilities to provide a great help for self-constructions of radiation measurement equipments, which needed huge cost and work to construct in the past. Then, I tried to construct a reasonable Mulch Channel Analyzer (MCA) with an educational FPGA board named EDX-005 (HuMANDATA ltd.), and conduct test measurements of the MCA. The MCA was constructed in a short period, and its cost was just under 50 thousands yen. The MCA normally works at 200 [cps/ch] count rate with a NaI(Tl) scintillation counter. The description of the MCA and some points of self-constructions of radiation measurement equipments are provided in this paper. (author)

  16. MCA Center of Excellence Through Benchmarking and INMM Involvement - Key Tools for Change

    Energy Technology Data Exchange (ETDEWEB)

    JAY, JEFFERY

    2005-10-07

    Nuclear Materials Management Department, a BWXT-corporate partner with Westinghouse Savannah River Company, has established a vision for positioning the organization as a Global Center of Excellence for Strategic Materials Management. NMM's Road to Excellence results from a changing business environment where flexibility and adaptability have become key demands from the Department of Energy customer. Flexibility and adaptability are integral components of the department's MC&A Center of Excellence philosophy in the pursuit of improvement technologies that meet domestic and international safeguards requirements. The customer challenge has put the organization in the forefront of change where benchmarking with other MC&A programs, applying human performance technologies and leveraging INMM leadership and participation opportunities are key ingredients to influencing improvements and changes in existing MC&A standards, policies and practices. The paper challenges MC&A professionals, MC&A program owners and organizational leaders to engage in the debate of new ideas, partnering arrangements and timely deployment of technologies (human performance and technical-based applications) to exponentially improve safeguards programs. Research and development efforts in support of safeguards improvements need to seriously consider deployment to field practitioners within a 2-3 year time frame from inception. INMM plays a crucial role in accelerating such opportunities and establishing improved performance standards above our normal governmental and organizational bureaucracies.

  17. Improving petroleum contaminated land remediation decision-making through the MCA weighting process.

    Science.gov (United States)

    Balasubramaniam, Anopama; Boyle, Alexander Rohan; Voulvoulis, Nikolaos

    2007-01-01

    Internationally petroleum contamination is widespread, posing serious environmental risks including surface and groundwater contamination, thus remediation is essential. The implementation of remediation options is becoming more complex with the increasing influence of stakeholders on the outcome of decision-making processes. Acceptance of remediation schemes during implementation can be increased by involving stakeholders and the public in the decision-making stage. In petroleum remediation involving multiple stakeholders, Multicriteria Analysis has been employed due to its ability to incorporate the preferences of each stakeholder through weighting. The research focused on investigating ways to improve the weighting process. The study demonstrated the utility of SWING, and determined which type of participant and how many participants to include in the decision process, through the application of ELECTRE III and Weighted Summation. It was recommended that a mixture of stakeholders, the public and experts be involved. The total number of participants will be limited by the choice of participatory and weighting methods. The careful selection of participants, as well as the choice of participatory and weighting methods, can minimize the subjectivity involved in MCA weighting, thereby lending decisions in petroleum remediation greater legitimacy.

  18. Dual Phases of Respiration Chain Defect-Augmented mROS-Mediated mCa2+ Stress during Oxidative Insult in Normal and ρ0 RBA1 Astrocytes

    Directory of Open Access Journals (Sweden)

    Tsung-I Peng

    2013-01-01

    Full Text Available Mitochondrial respiratory chain (RC deficits, resulting in augmented mitochondrial ROS (mROS generation, underlie pathogenesis of astrocytes. However, mtDNA-depleted cells (ρ0 lacking RC have been reported to be either sensitive or resistant to apoptosis. In this study, we sought to determine the effects of RC-enhanced mitochondrial stress following oxidative insult. Using noninvasive fluorescence probe-coupled laser scanning imaging microscopy, the ability to resist oxidative stress and levels of mROS formation and mitochondrial calcium (mCa2+ were compared between two different astrocyte cell lines, control and ρ0 astrocytes, over time upon oxidative stress. Our results showed that the cytoplasmic membrane becomes permeated with YO-PRO-1 dye at 150 and 130 minutes in RBA-1 and ρ0 astrocytes, respectively. In contrast to RBA-1, 30 minutes after 20 mM H2O2 exposure, ρ0 astrocytes formed marked plasma membrane blebs, lost the ability to retain Mito-R, and showed condensation of nuclei. Importantly, H2O2-induced ROS and accompanied mCa2+ elevation in control showed higher levels than ρ0 at early time point but vice versa at late time point. Our findings underscore dual phase of RC-defective cells harboring less mitochondrial stress due to low RC activity during short-term oxidative stress but augmented mROS-mediated mCa2+ stress during severe oxidative insult.

  19. A comparative study of mucin-like carcinoma-associated antigen (MCA), CA 125, CA 19-9 and CEA in patients with ovarian cancer.

    Science.gov (United States)

    Koelbl, H; Schieder, K; Neunteufel, W; Bieglmayer, C

    1989-01-01

    A mucin-like carcinoma associated antigen (MCA), which is recognized by the monoclonal antibody b-12, was found to be elevated in sera of breast cancer patients. Since an immunohistochemical reaction of the monoclonal antibody b-12 was found in epithelial tumors of the ovary we investigated MCA serum levels in 50 patients with ovarian cancer (mean age 59 years, range 31-81 years). In addition, CA 125, CA 19-9 and CEA were determined to compare sensitivity, specificity and the predictive value of the positive test of each parameter used in this study. Blood samples were obtained in 20 patients with progressive disease and in 30 patients during disease free intervals. The MCA serum levels of patients with progressive ovarian cancer (mean +/- SD: 14.7 +/- 14.6 U/ml) did not differ significantly from those of patients in remission (mean +/- SD: 8.2 +/- 5.3 U/ml) or from values of a healthy control group (mean +/- SD: 7.7 +/- 3.8 U/ml, n = 70). Women with progressive disease displayed significantly higher CA 125 (p less than 0.0001) and CEA (p less than 0.0063) serum levels than patients in remission. No significant difference was found for CA 19-9 in patients with ovarian cancer, irrespective of the clinical status. Considering marker surge and tumor progression, the highest sensitivity was found for CA 125 (75%). Sensitivities of the other markers were significantly lower and reached only 25-35%. The predictive value of elevated marker levels as well as specificity of the marker substances were similar. Sensitivity could be extended to 90% if elevation of CA 125, CA 19-9, CEA and MCA were taken into consideration, however specificity was lowered by using this marker combination.

  20. Norms and Standards for Computer Education (MCA, BCA) through Distance Mode.

    Science.gov (United States)

    Rausaria, R.R., Ed.; Lele, Nalini A., Ed.; Bhushan, Bharat, Ed.

    This document presents the norms and standards for computer education in India through distance mode, including the Masters in Computer Applications (MCA) and Bachelor in Computer Applications (BCA) programs. These norms and standards were considered and approved by the Distance Education Council, Indira Gandhi National Open University (India), at…

  1. Cerebral Arterial Time Constant Recorded from the MCA and PICA in Normal Subjects.

    Science.gov (United States)

    Kasprowicz, Magdalena; Czosnyka, Marek; Poplawska, Karolina; Reinhard, Matthias

    2016-01-01

    Cerebral arterial time constant (τ) estimates how quickly the cerebral arterial bed distal to the point of insonation is filled with arterial blood following a cardiac contraction. It is not known how τ behaves in different vascular territories in the brain. We therefore investigated the differences in τ of two cerebral arteries: the posterior inferior cerebellar artery (PICA) and the middle cerebral artery (MCA).Transcranial Doppler cerebral blood flow velocity (CBFV) in the PICA and left MCA along with Finapres arterial blood pressure (ABP) were simultaneously recorded in 35 young healthy volunteers. τ was estimated using mathematical transformations of pulse waveforms of ABP and the CBFV of the MCA and the PICA. Since τ is independent from the vessel radius, its comparison in different cerebral arteries was feasible. Mean ABP was 76.1 ± 9.6 mmHg. The CBFV of the MCA was higher than that of the PICA (59.7 ± 7.7 vs. 41.0 ± 4.5 cm/s; p blood volume. This study thus confirms the physiological validity of the τ concept. PMID:27165908

  2. Control of spatially heterogeneous and time-varying cellular reaction networks: a new summation law

    NARCIS (Netherlands)

    Peletier, M.A.; Westerhoff, H.V.; Kholodenko, B.N.

    2002-01-01

    A hallmark of a plethora of intracellular signaling pathways is the spatial separation of activation and deactivation processes that potentially results in precipitous gradients of activated proteins. The classical Metabolic Control Analysis (MCA), which quantifies the influence of an individual pro

  3. CONCEPT ANALYSIS OF PERCEIVED CONTROL

    OpenAIRE

    Mardiyono Mardiyono; Praneed Songwathana; Wongchan Petpichetchian

    2011-01-01

    Background. Perceived control is a personality characteristic that contributes psychological adjustment. It was derived from various theories, so that definitions of perceived control were ambiguous meaning. Disclosing concept of perceived control is required.Objective. The analysis aims to identify definition and use of perceived control, examine the basic attributes of perceived control, and the measurements of perceived control.Method. Databases searched for electronic journals and books t...

  4. Simultaneous detection and differentiation of Entamoeba histolytica, E. dispar, E. moshkovskii, Giardia lamblia and Cryptosporidium spp. in human fecal samples using multiplex PCR and qPCR-MCA.

    Science.gov (United States)

    Zebardast, Nozhat; Yeganeh, Farshid; Gharavi, Mohammad Javad; Abadi, Alireza; Seyyed Tabaei, Seyyed Javad; Haghighi, Ali

    2016-10-01

    Entamoeba histolytica, Giardia lamblia and Cryptosporidium spp. are common causes of diarrheal and intestinal diseases all over the world. Microscopic methods are useful in the diagnosis of intestinal parasites (IPs), but their sensitivity was assessed approximately 60 percent. Recently, molecular techniques have been used increasingly for the identification and characterization of the parasites. Among those, in this study we have used multiplex PCR and Real-time PCR with melting curve analysis (qPCR-MCA) for simultaneous detection and differentiation of E. histolytica, E. dispar, E. moshkovskii, G. lamblia and Cryptosporidium spp. in human fecal samples. Twenty DNA samples from 12 E. histolytica and 8 E. dispar samples and twenty stool samples confirmed positive for G. lamblia and Cryptosporidium spp. were analyzed. After DNA extraction from the samples, multiplex PCR was done for detection and differentiation of above mentioned parasites. QPCR-MCA was also performed for the detection and differentiation of 11 isolates of above mentioned parasite in a cycle with a time and temperature. Multiplex PCR was able to simultaneous detect and differentiate of above mentioned parasite in a single reaction. QPCR-MCA was able to differentiate genus and species those five protozoa using melting temperature simultaneously at the same time and temperature programs. In total, qPCR-MCA diagnosed 7/11 isolation of E. histolytica, 6/8 isolation of E. dispar, 1/1 E. moshkovskii Laredo, 10/11 G. Lamblia and 6/11 Cryptosporidium spp. Application of multiplex PCR for detection of more than one species in a test in developing countries, at least in reference laboratories has accurate diagnosis and plays a critical role in differentiation of protozoan species. Multiplex PCR assay with a template and multi template had different results and it seems that using a set of primers with one template has higher diagnostic capability in compare with multi template. The results of this study

  5. Simultaneous detection and differentiation of Entamoeba histolytica, E. dispar, E. moshkovskii, Giardia lamblia and Cryptosporidium spp. in human fecal samples using multiplex PCR and qPCR-MCA.

    Science.gov (United States)

    Zebardast, Nozhat; Yeganeh, Farshid; Gharavi, Mohammad Javad; Abadi, Alireza; Seyyed Tabaei, Seyyed Javad; Haghighi, Ali

    2016-10-01

    Entamoeba histolytica, Giardia lamblia and Cryptosporidium spp. are common causes of diarrheal and intestinal diseases all over the world. Microscopic methods are useful in the diagnosis of intestinal parasites (IPs), but their sensitivity was assessed approximately 60 percent. Recently, molecular techniques have been used increasingly for the identification and characterization of the parasites. Among those, in this study we have used multiplex PCR and Real-time PCR with melting curve analysis (qPCR-MCA) for simultaneous detection and differentiation of E. histolytica, E. dispar, E. moshkovskii, G. lamblia and Cryptosporidium spp. in human fecal samples. Twenty DNA samples from 12 E. histolytica and 8 E. dispar samples and twenty stool samples confirmed positive for G. lamblia and Cryptosporidium spp. were analyzed. After DNA extraction from the samples, multiplex PCR was done for detection and differentiation of above mentioned parasites. QPCR-MCA was also performed for the detection and differentiation of 11 isolates of above mentioned parasite in a cycle with a time and temperature. Multiplex PCR was able to simultaneous detect and differentiate of above mentioned parasite in a single reaction. QPCR-MCA was able to differentiate genus and species those five protozoa using melting temperature simultaneously at the same time and temperature programs. In total, qPCR-MCA diagnosed 7/11 isolation of E. histolytica, 6/8 isolation of E. dispar, 1/1 E. moshkovskii Laredo, 10/11 G. Lamblia and 6/11 Cryptosporidium spp. Application of multiplex PCR for detection of more than one species in a test in developing countries, at least in reference laboratories has accurate diagnosis and plays a critical role in differentiation of protozoan species. Multiplex PCR assay with a template and multi template had different results and it seems that using a set of primers with one template has higher diagnostic capability in compare with multi template. The results of this study

  6. An unexpected evolution of symptomatic mild middle cerebral artery (MCA stenosis: asymptomatic occlusion

    Directory of Open Access Journals (Sweden)

    Malferrari Giovanni

    2011-12-01

    Full Text Available Abstract Background The intracranial localization of large artery disease is recognized as the main cause of ischemic stroke in the world, considering all countries, although its global burden is widely underestimated. Indeed it has been reported more frequently in Asians and African-American people, but the finding of intracranial stenosis as a cause of ischemic stroke is relatively common also in Caucasians. The prognosis of patients with stroke due to intracranial steno-occlusion is strictly dependent on the time of recanalization. Moreover, the course of the vessel involvement is highly dynamic in both directions, improvement or worsening, although several data are derived from the atherosclerotic subtype, compared to other causes. Case description We report the clinical, neurosonological and neuroradiological findings of a young woman, who came to our Stroke Unit because of the abrupt onset of aphasia during her work. An urgent neurosonological examination showed a left M1 MCA stenosis, congruent with the presenting symptoms; magnetic resonance imaging confirmed this finding and identified an acute ischemic lesion on the left MCA territory. The past history of the patient was significant only for a hyperinsulinemic condition, treated with metformine, and a mild overweight. At this time a selective cerebral angiography was not performed because of the patient refusal and she was discharged on antiplatelet and lipid-lowering therapy, having failed to identify autoimmune or inflammatory diseases. Within 1 month, she went back to our attention because of the recurrence of aphasia, lasting about ten minutes. Neuroimaging findings were unchanged, but the patient accepted to undergo a selective cerebral angiography, which showed a mild left distal M1 MCA stenosis. During the follow-up the patient did not experienced any recurrence, but a routine neurosonological examination found an unexpected evolution of the known MCA stenosis, i.e. left M1 MCA

  7. CONCEPT ANALYSIS OF PERCEIVED CONTROL

    Directory of Open Access Journals (Sweden)

    Mardiyono Mardiyono

    2011-07-01

    Full Text Available Background. Perceived control is a personality characteristic that contributes psychological adjustment. It was derived from various theories, so that definitions of perceived control were ambiguous meaning. Disclosing concept of perceived control is required.Objective. The analysis aims to identify definition and use of perceived control, examine the basic attributes of perceived control, and the measurements of perceived control.Method. Databases searched for electronic journals and books that were published from 1994 to 2010 were analyzed.Result. Perceived control is personal belief that refers to controllability on behalf of one’s self and ability to control threats or events. The use of perceived control includes maternal, pediatric, medical, surgical, psychiatric, community nursing, and pain management. Perceived control was composed of two dimensions: belief about controllability and belief about ability to control to threats.Conclusion. Instrument of Anxiety Control Questionnaire most closely corresponds to two dimensions: belief about controllability and ability to control. Defining attributes and dimensions of perceived control are useful for developing tool.Keywords: perceived control, controllability, ability to control, and agency

  8. Submarine hydraulic control analysis

    OpenAIRE

    Bower, Michael J.

    1980-01-01

    Approved for public release; distribution unlimited A mathematical model was developed to include line effects in the submarine hydraulic system dynamic performance analysis. The project was undertaken in an effort to demonstrate the necessity of coupling the entire hydraulic power network for an accurate analysis of any of the subsystems rather than the current practice of treating a component loop as an isolated system. It was intended that the line model could be co...

  9. MCA4climate - a practical framework for pro-development climate policy

    DEFF Research Database (Denmark)

    Trevor, Morgan

    -operative action under the UN Climate Convention. It is crucial that those actions are designed within a coherent and robust policy-planning framework to ensure that they are both cost-e”ective and compatible with broader social, economic and environmental goals. For developing countries, sound climatepolicy....... Drawing upon best practices, tried and tested in other parts of the world, is clearly an advantage. The MCA4climate, a new UNEP initiative, is designed to assist policymakers, particularly in the developing world, in that endeavour. It o”ers concrete guidance and recommendations on a number of critical...... on climate policymaking from around the world and uses an innovative approach to assessing policies that ensures that climate policies and strategies take full account of developmental concerns and objectives. The MCA4climate initiative reflects UNEP’s mission to provide leadership and encourage partnership...

  10. NATO-ASTEC-matrix-research environment, information sharing and MCA

    International Nuclear Information System (INIS)

    The successful implementations of the NATO-ASTECMATRIX project in Armenia are essential contribution into security, stability and solidarity among regional nations, by applying the best technical expertise to problem solving. Collaboration, networking and capacity-building are means used to accomplish these goals. A further aim is to promote the co-operation with new partners and the ASTEC are creating links between scientists and organizations in formerly separated communities, developing new strategy concentrating support on security related collaborative projects and finding answers to critical questions and a way of connecting nations. The NATO-ASTECMATRIX within Armenia leads to a network of high standards laboratories that will drastically improve the overview and the technical infrastructure for monitoring, accounting and control of CBRN materials in the Armenia. This new infrastructure will enhance the exchange of information on this vital issue via the IRIS. In follow-up phases, it will also help to better define the needs and requirements for a policy to enhance legal tools for the management of these materials, and for the creation of one or several agencies aiming at dealing with wastes or no longer useful materials containing CBRN components in Armenia

  11. Treatment of a pediatric recurrent fusiform middle cerebral artery (MCA) aneurysm with a flow diverter.

    Science.gov (United States)

    Burrows, Anthony M; Zipfel, Gregory; Lanzino, Giuseppe

    2013-11-01

    Pediatric patients with aneurysm often have different localizations and morphologies from adults and recurrences are not uncommon after successful clip reconstruction/obliteration. Treatment of a recurrent pediatric aneurysm after clip ligation is a technical challenge. We present the case of an adolescent with a middle cerebral artery (MCA) fusiform aneurysm which recurred following clip reconstruction and bypass. The aneurysm was successfully treated with endovascular flow diversion.

  12. NuSTAR ground calibration: The Rainwater Memorial Calibration Facility (RaMCaF)

    DEFF Research Database (Denmark)

    Brejnholt, Nicolai; Christensen, Finn Erland; Jakobsen, Anders Clemen;

    2011-01-01

    The Nuclear Spectroscopic Telescope Array (NuSTAR) is a NASA Small Explorer mission that will carry the first focusing hard X-ray (5-80 keV ) telescope to orbit. The ground calibration of the three flight optics was carried out at the Rainwater Memorial Calibration Facility (RaMCaF) built for this...... purpose. In this article we present the facility and its use for the ground calibration of the three optics....

  13. Treatment of a pediatric recurrent fusiform middle cerebral artery (MCA) aneurysm with a flow diverter

    OpenAIRE

    Burrows, Anthony M; Zipfel, Gregory; Lanzino, Giuseppe

    2012-01-01

    Pediatric patients with aneurysm often have different localizations and morphologies from adults and recurrences are not uncommon after successful clip reconstruction/obliteration. Treatment of a recurrent pediatric aneurysm after clip ligation is a technical challenge. We present the case of an adolescent with a middle cerebral artery (MCA) fusiform aneurysm which recurred following clip reconstruction and bypass. The aneurysm was successfully treated with endovascular flow diversion.

  14. Effects of some ruthenium chelates on MCa mammary carcinoma and on TLX5 lymphoma in mice.

    Science.gov (United States)

    Bregant, F; Pacor, S; Ghosh, S; Chattopadhyay, S K; Sava, G

    1993-01-01

    A group of four Ruthenium chelates of the mixed hard/soft N-S donor ligands 2-formylpyridine (4-H/4-phenyl)thiosemicarbazone has been studied in the experimental models of MCa mammary carcinoma and TLX5 lymphoma in the CBA mouse. Although all the four tested complexes, bis-[2-formylpyridine(4- phenyl)thiosemicarbazone]ruthenium(II)chloride]Ru(L1)(L1H)Cl, 1], [2-formylpyridine(4-phenyl)thiosemicarbazone]ruthenium(II)-mu- trichloro chloro(imidazole)ruthenium(III)monomethanolate [Ru2(L1)(imz)Cl4.CH3OH, 9]. [2-formylpyridine(4-phenyl)thiosemicarbazone]dichloroimidazoler uthenium(II) [Ru(L1H)(imz)Cl2,10] and bis[2- formylpyridinethiosemicarbazone]ruthenium(II) perchlorate, dihydrate [Ru(L)(LH)ClO4.2H2O, 16], reduced the formation of lung metastases at the same extent only compound 1 caused parallel inhibition of the growth of the primary tumor. The chemical nature of the tested compounds seems to determine the nature of the antitumor effects and the bis-chelates are found to be endowed with greater cytotoxic properties towards primary tumor than the monochelates. This opens up a very interesting point, whether it is the presence of two chelate rings around the Ruthenium(II)/(III) acceptor centre or the increase in the number of the soft (S) donor centers that generates greater cytotoxic properties in the corresponding ruthenium complexes. As far as the reduction of the metastasis formation is concerned, it appears that among the four Ruthenium chelates tested, it is possible to identify structures capable of controlling the spread of tumor to the lungs in the absence of significant cytotoxicity for tumor cells. This finding appears of importance in that it indicates the possibility of a specific mechanism of interaction with cells of the metastatic tumor. In this context it appears necessary to investigate other congeners of this "family" with more sulfur donor sites and particularly those with better water solubility. PMID:8352519

  15. Subcubic Control Flow Analysis Algorithms

    DEFF Research Database (Denmark)

    Midtgaard, Jan; Van Horn, David

    We give the first direct subcubic algorithm for performing control flow analysis of higher-order functional programs. Despite the long held belief that inclusion-based flow analysis could not surpass the ``cubic bottleneck, '' we apply known set compression techniques to obtain an algorithm...

  16. 78 FR 67225 - Amendments to Material Control and Accounting Regulations

    Science.gov (United States)

    2013-11-08

    ... COMMISSION 10 CFR Parts 40, 70, 72, 74, and 150 RIN 3150-AI61 Amendments to Material Control and Accounting... Commission (NRC) is proposing to amend its regulations for material control and accounting (MC&A) of special... for control and accounting of SNM that is held by a licensee. The MC&A regulations ensure that...

  17. Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR

    Directory of Open Access Journals (Sweden)

    Lázcoz Paula

    2008-02-01

    Full Text Available Abstract Background We present two melting curve analysis (MCA-based semiquantitative real time PCR techniques to detect the promoter methylation status of genes. The first, MCA-MSP, follows the same principle as standard MSP but it is performed in a real time thermalcycler with results being visualized in a melting curve. The second, MCA-Meth, uses a single pair of primers designed with no CpGs in its sequence. These primers amplify both unmethylated and methylated sequences. In clinical applications the MSP technique has revolutionized methylation detection by simplifying the analysis to a PCR-based protocol. MCA-analysis based techniques may be able to further improve and simplify methylation analyses by reducing starting DNA amounts, by introducing an all-in-one tube reaction and by eliminating a final gel stage for visualization of the result. The current study aimed at investigating the feasibility of both MCA-MSP and MCA-Meth in the analysis of promoter methylation, and at defining potential advantages and shortcomings in comparison to currently implemented techniques, i.e. bisulfite sequencing and standard MSP. Methods The promoters of the RASSF1A (3p21.3, BLU (3p21.3 and MGMT (10q26 genes were analyzed by MCA-MSP and MCA-Meth in 13 astrocytoma samples, 6 high grade glioma cell lines and 4 neuroblastoma cell lines. The data were compared with standard MSP and validated by bisulfite sequencing. Results Both, MCA-MSP and MCA-Meth, successfully determined promoter methylation. MCA-MSP provided information similar to standard MSP analyses. However the analysis was possible in a single tube and avoided the gel stage. MCA-Meth proved to be useful in samples with intermediate methylation status, reflected by a melting curve position shift in dependence on methylation extent. Conclusion We propose MCA-MSP and MCA-Meth as alternative or supplementary techniques to MSP or bisulfite sequencing.

  18. Measurement Control Workshop Instructional Materials

    Energy Technology Data Exchange (ETDEWEB)

    Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Crawford, Cary [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McGinnis, Brent [Pacific Northwest National Lab. (PNNL), Richland, WA (United States) and Insolves LLC

    2014-04-01

    A workshop to teach the essential elements of an effective nuclear materials control and accountability (MC&A) programs are outlined, along with the modes of Instruction, and the roles and responsibilities of participants in the workshop.

  19. Measurement control workshop instructional materials

    Energy Technology Data Exchange (ETDEWEB)

    Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Crawford, Cary [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McGinnis, Brent [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Insolves LLC, Piketon, OH (United States)

    2014-04-01

    A workshop to teach the essential elements of an effective nuclear materials control and accountability (MC&A) programs are outlined, along with the modes of Instruction, and the roles and responsibilities of participants in the workshop.

  20. Controllability analysis of decentralised linear controllers for polymeric fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Serra, Maria; Aguado, Joaquin; Ansede, Xavier; Riera, Jordi [Institut de Robotica i Informatica Industrial, Universitat Politecnica de Catalunya - Consejo Superior de Investigaciones Cientificas, C. Llorens i Artigas 4, 08028 Barcelona (Spain)

    2005-10-10

    This work deals with the control of polymeric fuel cells. It includes a linear analysis of the system at different operating points, the comparison and selection of different control structures, and the validation of the controlled system by simulation. The work is based on a complex non linear model which has been linearised at several operating points. The linear analysis tools used are the Morari resiliency index, the condition number, and the relative gain array. These techniques are employed to compare the controllability of the system with different control structures and at different operating conditions. According to the results, the most promising control structures are selected and their performance with PI based diagonal controllers is evaluated through simulations with the complete non linear model. The range of operability of the examined control structures is compared. Conclusions indicate good performance of several diagonal linear controllers. However, very few have a wide operability range. (author)

  1. Video Game Control Dimensionality Analysis

    OpenAIRE

    Mustaquim, Moyen; Nyström, Tobias

    2014-01-01

    In this paper we have studied the video games control dimensionality and its effects on the traditional way of interpreting difficulty and familiarity in games. This paper presents the findings in which we have studied the Xbox 360 console’s games control dimensionality. Multivariate statistical operations were performed on the collected data from 83 different games of Xbox 360. It was found that the player’s perceived level of familiarity and difficulty can be influenced by the game control ...

  2. Modular Control Flow Analysis for Libraries

    DEFF Research Database (Denmark)

    Probst, Christian W.

    2002-01-01

    One problem in analyzing object oriented languages is that the exact control flow graph is not known statically due to dynamic dispatching. However, this is needed in order to apply the large class of known interprocedural analysis. Control Flow Analysis in the object oriented setting aims...... at determining run-time types of variables, thus allowing to possibly targeted method implementations. We present a flow sensitive analysis that allows separate handling of libraries and thereby efficient analysis of whole programs....

  3. Selecting supplier combination based on fuzzy multicriteria analysis

    Science.gov (United States)

    Han, Zhi-Qiu; Luo, Xin-Xing; Chen, Xiao-Hong; Yang, Wu-E.

    2015-07-01

    Existing multicriteria analysis (MCA) methods are probably ineffective in selecting a supplier combination. Thus, an MCA-based fuzzy 0-1 programming method is introduced. The programming relates to a simple MCA matrix that is used to select a single supplier. By solving the programming, the most feasible combination of suppliers is selected. Importantly, this result differs from selecting suppliers one by one according to a single-selection order, which is used to rank sole suppliers in existing MCA methods. An example highlights such difference and illustrates the proposed method.

  4. Birth outcomes of cases with unclassified multiple congenital abnormalities and pregnancy complications in their mothers depending on the number of component defects. Population-based case-control study.

    Science.gov (United States)

    Puhó, Erzsébet H; Czeizel, Andrew E; Acs, Nándor; Bánhidy, Ferenc

    2008-09-01

    Multiple congenital abnormalities (MCA) represent the most severe category of structural birth defects, (i.e. congenital abnormalities [CA]). Unfortunately, most MCA are not recognized and/or identified as MCA syndromes or MCA associations in the clinical practice. The term unclassified MCA (UMCA) is used for this category of MCA. We decided to evaluate the component CA of UMCA cases. The population-based large dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities (1980-1996) was evaluated. 'False' MCA, such as complex CA, polytopic field defects and sequences were excluded from the category of MCA. In addition, MCA syndromes caused by chromosomal aberrations and major mutant genes with preconceptional origin were excluded from the dataset of the Surveillance. MCA syndromes caused by teratogens and MCA associations with well-defined component CA were also excluded in the study. Thus, only UMCA cases (i) without the recognition of previously delineated MCA syndromes (ii) and/or without the identification of new MCA syndromes or (iii) caused by random combination of CA were included in the study. We compared data from 1349 cases with UMCA, 2405 matched population controls without any CA, and 21 494 malformed controls with isolated CA. There was a higher rate of stillbirth and a moderate male excess in UMCA cases, a somewhat shorter gestational age at delivery and an obvious reduction in birthweight. The intrauterine fetal growth retardation and rate of low-birthweight newborns showed an association with the number of component CA in UMCA cases. A similar association was not found with gestational age and the rate of preterm birth. UMCA represent one of the most severe categories of CA. The degree of intrauterine fetal growth retardation depends on number of component CA in UMCA cases.

  5. Iterative Learning Controller - Rate of Convergence Analysis

    OpenAIRE

    Shaikh, I. U. H., Khalili, H. H., Brown, M.

    2010-01-01

    Iterative Learning Control (ILC) is one of the Intelligent Control Systems which improves the transient performance of systems operating in a repetitive manner. After each repetition or batch, the controller learns to produce the best possible control input signal. Convergence analysis of the first order D - type ILC algorithm has been investigated. It generates the control input update for the next batch based on the derivative of the error between the desired and actual outputs during the c...

  6. LANMAS Gap Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Parrish, C.; Yee, W.; Okuda, V.; Watson, B.; Storch, N

    2000-08-25

    In July, 2000, the Controlled Materials Accountability and Tracking System (COMATS) Team, with the assistance of a representative of the Local Area Network Materials Accountability System (LANMAS) development team from Savannah River, performed an evaluation to enumerate and qualify differences between the current LANMAS functionality and LLNL requirements as implemented by COMATS. The differences found range from minor to serious deficiencies of LANMAS in relation to current LLNL MC&A practice. Therefore, we recommend a gradual integration of LANMAS into a hybrid system which uses LANMAS to satisfy DOE/NNSA MC&A and reporting requirements and uses COMATS to satisfy LLNL-specific MC&A and operational requirements.

  7. The vestibular control of balance after stroke

    OpenAIRE

    Marsden, J. F.; Playford, E. D.; Day, B. L.

    2005-01-01

    Objectives: To examine vestibular control of balance in those who recovered the ability to stand after middle cerebral artery (MCA) stroke.Methods: Sixteen patients with MCA stroke were compared with 10 age matched controls. Two additional patients were studied with isolated corticospinal tract lesions, one each at the level of the pons and medulla. Vestibular evoked postural responses were obtained using galvanic vestibular stimulation (GVS) while patients stood with their eyes closed and he...

  8. Adult Moyamoya disease: 320-Multidetector row CT for evaluation of revascularization in STA–MCA bypasses surgery

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Bing; Xu, Bing; Liu, Qi; Hao, Qiang; Lu, Jianping, E-mail: cjr.lujianping@vip.163.com

    2013-12-01

    Purpose: To evaluate the utility of 320-multidetector row whole-brain computed tomography perfusion (WBCTP) and whole-head subtracted dynamic angiography (WHSDCTA) for assessing the revascularization of blood flow after superficial temporal artery (STA) to middle cerebral artery (MCA) bypass surgery in adults with Moyamoya disease (MD) in the short and long term. Patients and methods: 320-multidetector row WBCTP and WHSDCTA were applied in 20 patients with MD before and after surgery (for an average of 3 days and 3 months). The bypass arteries were investigated using WHSDCTA and compared with DSA. The regions of interests (ROIs) in the surgical and mirror sides of the cerebral cortex were drawn on a Vitrea Workstation. Cerebral blood volume (CBV), time to peak (TTP), cerebral blood flow (CBF), mean transit time (MTT), and delay time were recorded. Preoperative and postoperative perfusion parameters in the MCA distribution were compared using the paired t-test. Results: WHSDCTA could clearly demonstrate 24 bypass arteries in 26 arteries for 20 patients, results which were in accordance with the results of digital subtraction angiography (DSA). When comparing preoperative values to those within 3 days after surgery, only TTP and delay time were significantly different (P < 0.05). Values of CBV, TTP, CBF, delay time, and MTT 3 months after surgery were significantly different (P < 0.05) from those of preoperative perfusion. Conclusion: These data suggest that 320-multidetector row WBCTP and WHSDCTA can be used to evaluate the revascularization of blood flow after STA–MCA bypass surgery in patients with MD in the short and long term.

  9. Adult Moyamoya disease: 320-Multidetector row CT for evaluation of revascularization in STA–MCA bypasses surgery

    International Nuclear Information System (INIS)

    Purpose: To evaluate the utility of 320-multidetector row whole-brain computed tomography perfusion (WBCTP) and whole-head subtracted dynamic angiography (WHSDCTA) for assessing the revascularization of blood flow after superficial temporal artery (STA) to middle cerebral artery (MCA) bypass surgery in adults with Moyamoya disease (MD) in the short and long term. Patients and methods: 320-multidetector row WBCTP and WHSDCTA were applied in 20 patients with MD before and after surgery (for an average of 3 days and 3 months). The bypass arteries were investigated using WHSDCTA and compared with DSA. The regions of interests (ROIs) in the surgical and mirror sides of the cerebral cortex were drawn on a Vitrea Workstation. Cerebral blood volume (CBV), time to peak (TTP), cerebral blood flow (CBF), mean transit time (MTT), and delay time were recorded. Preoperative and postoperative perfusion parameters in the MCA distribution were compared using the paired t-test. Results: WHSDCTA could clearly demonstrate 24 bypass arteries in 26 arteries for 20 patients, results which were in accordance with the results of digital subtraction angiography (DSA). When comparing preoperative values to those within 3 days after surgery, only TTP and delay time were significantly different (P < 0.05). Values of CBV, TTP, CBF, delay time, and MTT 3 months after surgery were significantly different (P < 0.05) from those of preoperative perfusion. Conclusion: These data suggest that 320-multidetector row WBCTP and WHSDCTA can be used to evaluate the revascularization of blood flow after STA–MCA bypass surgery in patients with MD in the short and long term

  10. Stray light analysis and control

    CERN Document Server

    Fest, Eric

    2013-01-01

    Stray light is defined as unwanted light in an optical system, a familiar concept for anyone who has taken a photograph with the sun in or near their camera's field of view. This book addresses stray light terminology, radiometry, and the physics of stray light mechanisms, such as surface roughness scatter and ghost reflections. The most-efficient ways of using stray light analysis software packages are included. The book also demonstrates how the basic principles are applied in the design, fabrication, and testing phases of optical system development.

  11. Thermal and stress analysis of control rod

    International Nuclear Information System (INIS)

    In order to survey the mechanical integrity of a control rod in the high temperature core of the VHTR, thermal analysis and thermal stress analysis were carried out by means of calculus of finite differentials and finite element methods for the plant under the normal operating condition as well as under several abnormal conditions. The results of the analyses have been applied to refine the mechanical design of the control rod

  12. Control Flow Analysis for BioAmbients

    DEFF Research Database (Denmark)

    Nielson, Flemming; Nielson, Hanne Riis; Priami, C.;

    2007-01-01

    This paper presents a static analysis for investigating properties of biological systems specified in BioAmbients. We exploit the control flow analysis to decode the bindings of variables induced by communications and to build a relation of the ambients that can interact with each other. We...

  13. Ivy signs on FLAIR images before and after STA-MCA anastomosis in patients with Moyamoya disease

    Energy Technology Data Exchange (ETDEWEB)

    Ideguchi, Reiko; Enokizono, Mikako; Uetani, Masataka (Dept. of Radiological Sciences, Nagasaki Univ. Graduate School of Biomedical Sciences, Nagasaki (Japan)), e-mail: qqtt37gd9@forest.ocn.ne.jp; Morikawa, Minoru (Dept. of Radiology, Nagasaki Univ. School of Medicine, Nagasaki (Japan)); Ogawa, Yoji (Dept. of Radiology, Hanwa Daini Senboku Hospital, Osaka (Japan)); Nagata, Izumi (Dept. of Neurosurgery, Nagasaki Univ. School of Medicine, Nagasaki (Japan))

    2011-04-15

    Background: Leptomeningeal high signal intensity (ivy sign) on fluid-attenuated inversion-recovery (FLAIR) MR imaging is one of the features of Moyamoya disease. However, the correlation between ivy sign and cerebral perfusion status has not been fully evaluated. Purpose: To characterize ivy sign on FLAIR images in Moyamoya disease and compare this finding with hemodynamic alterations on perfusion single-photon emission CT (SPECT) obtained before and after bypass surgery. Material and Methods: Sixteen patients with angiographically confirmed Moyamoya disease who underwent superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis were included in the study. The presence of ivy sign on FLAIR images was classified as 'negative', 'minimal' and 'positive'. We evaluated the relationship between ivy sign and findings of SPECT, including cerebral vascular reserve (CVR) before and after surgery. Results: Minimal or positive ivy sign was seen in 13 (81%) of 16 patients, and 21 (66%) of 32 hemispheres. CVR in the areas with positive or minimal ivy sign was lower than that in the areas with negative ivy sign. After STA-MCA anastomosis, ivy sign disappeared or decreased in all 21 hemispheres demonstrating ivy sign. SPECT demonstrated apparent hemodynamic improvement in areas demonstrating disappearance or decrease of ivy sign. Conclusion: Ivy sign on FLAIR image is seen in areas with decreased cerebral perfusion. The sign is useful for non-invasive assessment of cerebral hemodynamic status before and after surgery

  14. Aircraft Loss-of-Control Accident Analysis

    Science.gov (United States)

    Belcastro, Christine M.; Foster, John V.

    2010-01-01

    Loss of control remains one of the largest contributors to fatal aircraft accidents worldwide. Aircraft loss-of-control accidents are complex in that they can result from numerous causal and contributing factors acting alone or (more often) in combination. Hence, there is no single intervention strategy to prevent these accidents. To gain a better understanding into aircraft loss-of-control events and possible intervention strategies, this paper presents a detailed analysis of loss-of-control accident data (predominantly from Part 121), including worst case combinations of causal and contributing factors and their sequencing. Future potential risks are also considered.

  15. Integrated tools for control-system analysis

    Science.gov (United States)

    Ostroff, Aaron J.; Proffitt, Melissa S.; Clark, David R.

    1989-01-01

    The basic functions embedded within a user friendly software package (MATRIXx) are used to provide a high level systems approach to the analysis of linear control systems. Various control system analysis configurations are assembled automatically to minimize the amount of work by the user. Interactive decision making is incorporated via menu options and at selected points, such as in the plotting section, by inputting data. There are five evaluations such as the singular value robustness test, singular value loop transfer frequency response, Bode frequency response, steady-state covariance analysis, and closed-loop eigenvalues. Another section describes time response simulations. A time response for random white noise disturbance is available. The configurations and key equations used for each type of analysis, the restrictions that apply, the type of data required, and an example problem are described. One approach for integrating the design and analysis tools is also presented.

  16. Analysis and control of underactuated mechanical systems

    CERN Document Server

    Choukchou-Braham, Amal; Djemaï, Mohamed; Busawon, Krishna

    2014-01-01

    This monograph provides readers with tools for the analysis, and control of systems with fewer control inputs than degrees of freedom to be controlled, i.e., underactuated systems. The text deals with the consequences of a lack of a general theory that would allow methodical treatment of such systems and the ad hoc approach to control design that often results, imposing a level of organization whenever the latter is lacking. The authors take as their starting point the construction of a graphical characterization or control flow diagram reflecting the transmission of generalized forces through the degrees of freedom. Underactuated systems are classified according to the three main structures by which this is found to happen—chain, tree, and isolated vertex—and control design procedures proposed. The procedure is applied to several well-known examples of underactuated systems: acrobot; pendubot; Tora system; ball and beam; inertia wheel; and robotic arm with elastic joint. The text is illustrated with MATL...

  17. Analysis and design of hybrid control systems

    Energy Technology Data Exchange (ETDEWEB)

    Malmborg, J.

    1998-05-01

    Different aspects of hybrid control systems are treated: analysis, simulation, design and implementation. A systematic methodology using extended Lyapunov theory for design of hybrid systems is developed. The methodology is based on conventional control designs in separate regions together with a switching strategy. Dynamics are not well defined if the control design methods lead to fast mode switching. The dynamics depend on the salient features of the implementation of the mode switches. A theorem for the stability of second order switching together with the resulting dynamics is derived. The dynamics on an intersection of two sliding sets are defined for two relays working on different time scales. The current simulation packages have problems modeling and simulating hybrid systems. It is shown how fast mode switches can be found before or during simulation. The necessary analysis work is a very small overhead for a modern simulation tool. To get some experience from practical problems with hybrid control the switching strategy is implemented in two different software environments. In one of them a time-optimal controller is added to an existing PID controller on a commercial control system. Successful experiments with this hybrid controller shows the practical use of the method 78 refs, 51 figs, 2 tabs

  18. PROMETHEE Method and Sensitivity Analysis in the Software Application for the Support of Decision-Making

    Directory of Open Access Journals (Sweden)

    Petr Moldrik

    2008-01-01

    Full Text Available PROMETHEE is one of methods, which fall into multi-criteria analysis (MCA. The MCA, as the name itself indicates, deals with the evaluation of particular variants according to several criteria. Developed software application (MCA8 for the support of multi-criteria decision-making was upgraded about PROMETHEE method and a graphic tool, which enables the execution of the sensitivity analysis. This analysis is used to ascertain how a given model output depends upon the input parameters. The MCA8 software application with mentioned graphic upgrade was developed for purposes of solving multi-criteria decision tasks. In the MCA8 is possible to perform sensitivity analysis by a simple form – through column graphs. We can change criteria significances (weights in these column graphs directly and watch the changes of the order of variants immediately.

  19. The Analysis of Rail Traffic Control Systems

    Directory of Open Access Journals (Sweden)

    Darius Gaidelis

    2011-04-01

    Full Text Available The systems used for rail traffic control are compared. Their advantages and disadvantages are analysed. The present and future development of rail traffic control systems in various countries is considered. The possibility of adapting these microprocessor-based traffic control systems to the conditions of Lithuania is analysed. For this purpose, the analysis of goods transported by Lithuanian railways is made, and the non-uniform amount of goods transported on different road sections is evaluated. The number of the delayed trains due to the failure of traffic control systems in recent years is determined, the cost of installing a new microprocessor-based traffic control system at the railway station, as well as its repay time and the demand for employees are calculated. Article in Lithuanian

  20. Power system stability modelling, analysis and control

    CERN Document Server

    Sallam, Abdelhay A

    2015-01-01

    This book provides a comprehensive treatment of the subject from both a physical and mathematical perspective and covers a range of topics including modelling, computation of load flow in the transmission grid, stability analysis under both steady-state and disturbed conditions, and appropriate controls to enhance stability.

  1. Financial Analysis, Budgeting, Decision and Control

    Directory of Open Access Journals (Sweden)

    Mariana Rodica TIRLEA

    2013-12-01

    Full Text Available The economic processes taking place in the economic environment are stochastic processes that involve and imply risks, arising from product diversification, competition, financial derivatives transactions: swaps, futures, options and from the large number of actors involved in the stock market with a higher or a smaller uncertainty degree. Competition and competitiveness, led to major and rapid change in the business environment, they determined actors participating in the economy to find solutions and methods of collecting and processing data, in such a way that, after being transformed into information they quickly help based on their analysis in decision making, planning and financial forecasting, having an effect on increasing their economic efficiency. In these circumstances the financial analysis, decision, forecasting and control, should be based on quality information that should be a value creation source. The active nature of the financial function implies the existence of a substantially large share of financial analysis, financial decision, forecasting and control.

  2. Analysis and control of distributed cooperative systems.

    Energy Technology Data Exchange (ETDEWEB)

    Feddema, John Todd; Parker, Eric Paul; Wagner, John S.; Schoenwald, David Alan

    2004-09-01

    As part of DARPA Information Processing Technology Office (IPTO) Software for Distributed Robotics (SDR) Program, Sandia National Laboratories has developed analysis and control software for coordinating tens to thousands of autonomous cooperative robotic agents (primarily unmanned ground vehicles) performing military operations such as reconnaissance, surveillance and target acquisition; countermine and explosive ordnance disposal; force protection and physical security; and logistics support. Due to the nature of these applications, the control techniques must be distributed, and they must not rely on high bandwidth communication between agents. At the same time, a single soldier must easily direct these large-scale systems. Finally, the control techniques must be provably convergent so as not to cause undo harm to civilians. In this project, provably convergent, moderate communication bandwidth, distributed control algorithms have been developed that can be regulated by a single soldier. We have simulated in great detail the control of low numbers of vehicles (up to 20) navigating throughout a building, and we have simulated in lesser detail the control of larger numbers of vehicles (up to 1000) trying to locate several targets in a large outdoor facility. Finally, we have experimentally validated the resulting control algorithms on smaller numbers of autonomous vehicles.

  3. Statistical quality control through overall vibration analysis

    Science.gov (United States)

    Carnero, M. a. Carmen; González-Palma, Rafael; Almorza, David; Mayorga, Pedro; López-Escobar, Carlos

    2010-05-01

    The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers' safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities. Noise and vibration are common quality problems in bearings. These failure modes likely occur under certain operating conditions and do not require high vibration amplitudes but relate to certain vibration frequencies. The vibration frequencies are affected by the type of surface problems (chattering) of ball races that are generated through grinding processes. The purpose of this paper is to identify grinding process variables that affect the quality of bearings by using statistical principles in the field of machine tools. In addition, an evaluation of the quality results of the finished parts under different combinations of process variables is assessed. This paper intends to establish the foundations to predict the quality of the products through the analysis of self-induced vibrations during the contact between the grinding wheel and the parts. To achieve this goal, the overall self-induced vibration readings under different combinations of process variables are analysed using statistical tools. The analysis of data and design of experiments follows a classical approach, considering all potential interactions between variables. The analysis of data is conducted through analysis of variance (ANOVA) for data sets that meet normality and homoscedasticity criteria. This paper utilizes different statistical tools to support the conclusions such as chi squared, Shapiro-Wilks, symmetry, Kurtosis, Cochran, Hartlett, and Hartley and Krushal-Wallis. The analysis presented is the starting point to extend the use of predictive techniques (vibration analysis) for quality control. This paper demonstrates the existence

  4. Quantitative resilience analysis through control design.

    Energy Technology Data Exchange (ETDEWEB)

    Sunderland, Daniel; Vugrin, Eric D.; Camphouse, Russell Chris (Sandia National Laboratories, Carlsbad, NM)

    2009-09-01

    Critical infrastructure resilience has become a national priority for the U. S. Department of Homeland Security. System resilience has been studied for several decades in many different disciplines, but no standards or unifying methods exist for critical infrastructure resilience analysis. Few quantitative resilience methods exist, and those existing approaches tend to be rather simplistic and, hence, not capable of sufficiently assessing all aspects of critical infrastructure resilience. This report documents the results of a late-start Laboratory Directed Research and Development (LDRD) project that investigated the development of quantitative resilience through application of control design methods. Specifically, we conducted a survey of infrastructure models to assess what types of control design might be applicable for critical infrastructure resilience assessment. As a result of this survey, we developed a decision process that directs the resilience analyst to the control method that is most likely applicable to the system under consideration. Furthermore, we developed optimal control strategies for two sets of representative infrastructure systems to demonstrate how control methods could be used to assess the resilience of the systems to catastrophic disruptions. We present recommendations for future work to continue the development of quantitative resilience analysis methods.

  5. Connectivity analysis of controlled quantum systems

    Science.gov (United States)

    Wu, Rong; Rabitz, Herschel; Turinici, Gabriel; Sola, Ignacio

    2004-11-01

    A connectivity analysis of controlled quantum systems assesses the feasibility of a field existing that can transfer at least some amplitude between any specified pair of states. Although Hamiltonians with special structure or symmetry may not produce full connectivity, it is argued and demonstrated that virtually any Hamiltonian is expected to be connected. The connectivity of any particular system is generally revealed in the quantum evolution over a single or at most a few time steps. A connectivity analysis is inexpensive to perform and it can also identify statistically significant intermediate states linking a specified initial and final state. These points are illustrated with several simple systems. The likelihood of an arbitrary system being connected implies that at least some product yield can be expected in the laboratory for virtually all systems subjected to a suitable control.

  6. Project evaluation, sustainability and accountability : combining cost-benefit analysis (CBA) and multi-criteria analysis (MCA)

    NARCIS (Netherlands)

    Sijtsma, F.J.

    2006-01-01

    General abstract Decision-makers in governments and businesses must choose among different project alternatives which, in varying degrees, contribute to sustainability. Decision-makers also have to account for their choices to a large audience or a broad range of stakeholders. This thesis is about t

  7. Application of dimensional analysis in systems modeling and control design

    CERN Document Server

    Balaguer, Pedro

    2013-01-01

    Dimensional analysis is an engineering tool that is widely applied to numerous engineering problems, but has only recently been applied to control theory and problems such as identification and model reduction, robust control, adaptive control, and PID control. Application of Dimensional Analysis in Systems Modeling and Control Design provides an introduction to the fundamentals of dimensional analysis for control engineers, and shows how they can exploit the benefits of the technique to theoretical and practical control problems.

  8. Human reliability analysis of control room operators

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A.L.; Carvalho, Paulo Victor R.; Grecco, Claudio H.S. [Instituto de Engenharia Nuclear (IEN), Rio de Janeiro, RJ (Brazil)

    2005-07-01

    Human reliability is the probability that a person correctly performs some system required action in a required time period and performs no extraneous action that can degrade the system Human reliability analysis (HRA) is the analysis, prediction and evaluation of work-oriented human performance using some indices as human error likelihood and probability of task accomplishment. Significant progress has been made in the HRA field during the last years, mainly in nuclear area. Some first-generation HRA methods were developed, as THERP (Technique for human error rate prediction). Now, an array of called second-generation methods are emerging as alternatives, for instance ATHEANA (A Technique for human event analysis). The ergonomics approach has as tool the ergonomic work analysis. It focus on the study of operator's activities in physical and mental form, considering at the same time the observed characteristics of operator and the elements of the work environment as they are presented to and perceived by the operators. The aim of this paper is to propose a methodology to analyze the human reliability of the operators of industrial plant control room, using a framework that includes the approach used by ATHEANA, THERP and the work ergonomics analysis. (author)

  9. Large scale systems approximation: Analysis and control

    International Nuclear Information System (INIS)

    This work concerns the study of the approximation of high dimensional systems by low order models. This approximation is defined by aggregation methods, the method based on singular perturbations and a relatively recent method. This later one is formulated in a particular representation of the system and is called balanced realisation method. The application of the approximation is then studied in the case of suboptimal control theory for the several defined models. The results of numerical simulation for the analysis and control are carried on two examples defined by a model of a nuclear reactor core of order nine and a steam generator of a fuel station of order twenty and permitted to develop a comparative study of the performances of the different methods analysed in the case of open loop and closed loop models

  10. Design and Simulation of Seido Buffer for Analog to Digital Converter (ADC) on Multichannel Analyzer (MCA) Application

    International Nuclear Information System (INIS)

    Most of our electronic equipment has buffer, thus this make buffer as one of importance in electronic gadget. This paper introduced Single Ended Input Differential Output (SEIDO) buffer to predict the bias at approximately 2.5 V. For this purpose, the input range between -1 mV to 4 V was implemented. The software used to cascade SEIDO buffer is called LTspice IV; an open source software developed by Linear Technology Incorporation. The component involve in this development was Operational Amplifier (OP AMP) AD826 from Analog Devices Incorporation, capacitor and resistor. Kirchhoffs Current Law and Kirchhoffs Voltage Law was applied to calculated voltage gain and biasing voltage. All design has been verified by LTspice IV. The result produced from simulation was between -0.3 V to 6.3 V with bias roughly at 2.5 V. These results prove that it was capable to drive Analog Digital Converter (ADC) that can subsequently apply for Multichannel Analyzer (MCA). (author)

  11. Radioactivity analysis of food and accuracy control

    International Nuclear Information System (INIS)

    From the fact that radioactive substances have been detected from the foods such as agricultural and livestock products and marine products due to the accident of the Fukushima Daiichi Nuclear Power Station of Tokyo Electric Power Company, the Ministry of Health, Labour and Welfare stipulated new standards geared to general foods on radioactive cesium by replacing the interim standards up to now. Various institutions began to measure radioactivity on the basis of this instruction, but as a new challenge, a problem of the reliability of the data occurred. Therefore, accuracy control to indicate the proof that the quality of the data can be retained at an appropriate level judging from an objective manner is important. In order to consecutively implement quality management activities, it is necessary for each inspection agency to build an accuracy control system. This paper introduces support service, as a new attempt, for establishing the accuracy control system. This service is offered jointly by three organizations, such as TUV Rheinland Japan Ltd., Japan Frozen Foods Inspection Corporation, and Japan Chemical Analysis Center. This service consists of the training of radioactivity measurement practitioners, proficiency test for radioactive substance measurement, and personal authentication. (O.A.)

  12. Improving Software Systems By Flow Control Analysis

    Directory of Open Access Journals (Sweden)

    Piotr Poznanski

    2012-01-01

    Full Text Available Using agile methods during the implementation of the system that meets mission critical requirements can be a real challenge. The change in the system built of dozens or even hundreds of specialized devices with embedded software requires the cooperation of a large group of engineers. This article presents a solution that supports parallel work of groups of system analysts and software developers. Deployment of formal rules to the requirements written in natural language enables using formal analysis of artifacts being a bridge between software and system requirements. Formalism and textual form of requirements allowed the automatic generation of message flow graph for the (sub system, called the “big-picture-model”. Flow diagram analysis helped to avoid a large number of defects whose repair cost in extreme cases could undermine the legitimacy of agile methods in projects of this scale. Retrospectively, a reduction of technical debt was observed. Continuous analysis of the “big picture model” improves the control of the quality parameters of the software architecture. The article also tries to explain why the commercial platform based on UML modeling language may not be sufficient in projects of this complexity.

  13. Technical specification for the vacuum chamber assemblies comprising flexible metal bellows, transition pieces, flanges and vacuum tubes for the magnets MCA/MCB in the experimental areas of the 450 GeV proton synchrotron

    CERN Document Server

    CERN. Geneva

    1988-01-01

    Technical specification for the vacuum chamber assemblies comprising flexible metal bellows, transition pieces, flanges and vacuum tubes for the magnets MCA/MCB in the experimental areas of the 450 GeV proton synchrotron

  14. Robustness analysis applied to substructure controller synthesis

    Science.gov (United States)

    Gonzalez-Oberdoerffer, Marcelo F.; Craig, Roy R., Jr.

    1993-01-01

    The stability and robustness of the controlled system obtained via the substructure control synthesis (SCS) method of Su et al. (1990) were examined using a six-bay truss model, and employing an LQG control design method to obtain controllers for two separate structures. It is found that the assembled controller provides a stability in this instance. A qualitative assessment of the stability robustness of the system with controller designed with the SCS method is provided by obtaining a controller using the complete truss model and comparing the robustness of the corresponding closed-loop systems.

  15. Risk Analysis of Safety-Critical Control Systems

    OpenAIRE

    Karol Rastocny

    2008-01-01

    This paper deals with problems associated with risks analysis of a safety-critical control system. In the paper there are introduced recommendations enabling practical enforceability of risk analysis by the assurance of sufficient objectivity level. In the initial phases of the system lifecycle risk analysis serves for a tolerable hazard rate definition for individual safety relevant functions. In the end of the control system development process the risk analysis (an analysis of failures con...

  16. Power flow analysis for DC voltage droop controlled DC microgrids

    DEFF Research Database (Denmark)

    Li, Chendan; Chaudhary, Sanjay; Dragicevic, Tomislav;

    2014-01-01

    This paper proposes a new algorithm for power flow analysis in droop controlled DC microgrids. By considering the droop control in the power flow analysis for the DC microgrid, when compared with traditional methods, more accurate analysis results can be obtained. The algorithm verification is ca...

  17. A Calculus for Control Flow Analysis of Security Protocols

    DEFF Research Database (Denmark)

    Buchholtz, Mikael; Nielson, Hanne Riis; Nielson, Flemming

    2004-01-01

    analysis methodology. We pursue an analysis methodology based on control flow analysis in flow logic style and we have previously shown its ability to analyse a variety of security protocols. This paper develops a calculus, LysaNS that allows for much greater control and clarity in the description...

  18. Team One (GA/MCA) effort of the DOE 12 Tesla Coil Development Program. Progress report for the two quarters ending March 31, 1981

    International Nuclear Information System (INIS)

    This report covers progress by Team One of the DOE/OFE/D and T 12 Tesla Coil Development Program during the first and second quarters of fiscal 1981. General Atomic Company is the Team One leader, with Magnetic Corporation of America (MCA) as industrial subcontractor. The basic mission of this effort is to demonstrate the feasibility of, and establish an engineering data base for utilizing bath cooled NbTi alloy to generate a peak toroidal field of 12 tesla in a tokamak reactor

  19. Explicit model predictive control accuracy analysis

    OpenAIRE

    Knyazev, Andrew; Zhu, Peizhen; Di Cairano, Stefano

    2015-01-01

    Model Predictive Control (MPC) can efficiently control constrained systems in real-time applications. MPC feedback law for a linear system with linear inequality constraints can be explicitly computed off-line, which results in an off-line partition of the state space into non-overlapped convex regions, with affine control laws associated to each region of the partition. An actual implementation of this explicit MPC in low cost micro-controllers requires the data to be "quantized", i.e. repre...

  20. KAP Surveys and Dengue Control in Colombia: Disentangling the Effect of Sociodemographic Factors Using Multiple Correspondence Analysis

    Science.gov (United States)

    Quintero, Juliana

    2016-01-01

    During the last few decades, several studies have analyzed and described knowledge, attitudes, and practices (KAP) of populations regarding dengue. However, few studies have applied geometric data analytic techniques to generate indices from KAP domains. Results of such analyses have not been used to determine the potential effects of sociodemographic variables on the levels of KAP. The objective was to determine the sociodemographic factors related to different levels of KAP regarding dengue in two hyper-endemic cities of Colombia, using a multiple correspondence analysis (MCA) technique. In the context of a cluster randomized trial, 3,998 households were surveyed in Arauca and Armenia between 2012 and 2013. To generate KAP indexes, we performed a MCA followed by a hierarchical cluster analysis to classify each score in different groups. A quantile regression for each of the score groups was conducted. KAP indexes explained 56.1%, 79.7%, and 83.2% of the variance, with means of 4.2, 1.4, and 3.2 and values that ranged from 1 to 7, 7 and 11, respectively. The highest values of the index denoted higher levels of knowledge and practices. The attitudes index did not show the same relationship and was excluded from the analysis. In the quantile regression, age (0.06; IC: 0.03, 0.09), years of education (0.14; IC: 0.06, 0.22), and history of dengue in the family (0.21; IC: 0.12, 0.31) were positively related to lower levels of knowledge regarding dengue. The effect of such factors gradually decreased or disappeared when knowledge was higher. The practices indexes did not evidence a correlation with sociodemographic variables. These results suggest that the transformation of categorical variables into a single index by the use of MCA is possible when analyzing knowledge and practices regarding dengue from KAP questionnaires. Additionally, the magnitude of the effect of socioeconomic variables on the knowledge scores varies according to the levels of knowledge, suggesting

  1. Adaptive Control Algorithms, Analysis and Applications

    OpenAIRE

    Landau, Ioan; Lozano, Rogelio; M'Saad, Mohammed; Karimi, Alireza

    2011-01-01

    Adaptive Control (second edition) shows how a desired level of system performance can be maintained automatically and in real time, even when process or disturbance parameters are unknown and variable. It is a coherent exposition of the many aspects of this field, setting out the problems to be addressed and moving on to solutions, their practical significance and their application. Discrete-time aspects of adaptive control are emphasized to reflect the importance of digital computers in the ...

  2. Hybrid formulations of liposomes and bioadhesive polymers improve the hypotensive effect of the melatonin analogue 5-MCA-NAT in rabbit eyes.

    Directory of Open Access Journals (Sweden)

    Daniela Quinteros

    Full Text Available For the treatment of chronic ocular diseases such as glaucoma, continuous instillations of eye drops are needed. However, frequent administrations of hypotensive topical formulations can produce adverse ocular surface effects due to the active substance or other components of the formulation, such as preservatives or other excipients. Thus the development of unpreserved formulations that are well tolerated after frequent instillations is an important challenge to improve ophthalmic chronic topical therapies. Furthermore, several components can improve the properties of the formulation in terms of efficacy. In order to achieve the mentioned objectives, we have developed formulations of liposomes (150-200 nm containing components similar to those in the tear film and loaded with the hypotensive melatonin analog 5-methoxycarbonylamino-N-acetyltryptamine (5-MCA-NAT, 100 µM. These formulations were combined with mucoadhesive (sodium hyaluronate or carboxymethylcellulose or amphiphilic block thermosensitive (poloxamer polymers to prolong the hypotensive efficacy of the drug. In rabbit eyes, the decrease of intraocular pressure with 5-MCA-NAT-loaded liposomes that were dispersed with 0.2% sodium hyaluronate, 39.1±2.2%, was remarkably higher compared to other liposomes formulated without or with other bioadhesive polymers, and the effect lasted more than 8 hours. According to the results obtained in the present work, these technological strategies could provide an improved modality for delivering therapeutic agents in patients with glaucoma.

  3. The pharmacologic inhibition of the xc- antioxidant system improves the antitumor efficacy of COX inhibitors in the in vivo model of 3-MCA tumorigenesis.

    Science.gov (United States)

    Balza, Enrica; Castellani, Patrizia; Delfino, Laura; Truini, Mauro; Rubartelli, Anna

    2013-03-01

    The chemopreventive and therapeutic efficacy of the cyclooxygenase (COX) inhibitor ibuprofen (IB) and of sulfasalazine (SASP), a drug that targets the antioxidant xc- system, were exploited in the experimental model of 3-methylcholantrene (3-MCA)-induced mouse sarcoma. The chemopreventive treatments gave unsatisfactory results because administration of IB one day after the 3-MCA injection only slightly delayed the tumor development, whereas SASP dispensed under the same conditions resulted in accelerated tumorigenesis. Similarly, the therapeutic treatment with either drug, administrated daily from the tumor detection, decreased the proliferation rate of tumor cells and increased the survival of treated mice only at a low extent. Remarkably, the combined chemopreventive treatment with IB and therapeutic treatment with SASP displayed a better efficacy, with strong delay of sarcoma growth, reduced tumor size and increased survival of treated mice. The two drugs target not only tumor cells but also tumor-associated macrophages that were dramatically decreased in the tumor infiltrate of mice subjected to the combined treatment. The synergistic effects of the association between a broad anti-inflammatory compound, such as IB, and a redox-directed drug, such as SASP, shed new light in the role of inflammation and of the redox response in chemical tumorigenesis and point to the combined chemopreventive plus therapeutic treatment with IB and SASP as a promising novel approach for antitumor therapy.

  4. Integration of Design and Control Through Model Analysis

    DEFF Research Database (Denmark)

    Russel, Boris Mariboe; Henriksen, Jens Peter; Jørgensen, Sten Bay;

    2000-01-01

    A systematic analysis of the process model is proposed as a pre-solution step for integration of design and control problems. It is shown that the same set of process (control) variables and design (manipulative) variables is employed with different objectives in design and control. Analysis...... of the phenomena models representing the process model identify the relationships between the important process and design variables, which help to understand, define and address some of the issues related to integration of design and control issues. The model analysis is highlighted through examples involving...... processes with mass and/or energy recycle. (C) 2000 Elsevier Science Ltd. All rights reserved....

  5. INTERNAL AUDIT COMPARATIVE ANALYSIS - MANAGEMENT CONTROL CONCEPTS

    Directory of Open Access Journals (Sweden)

    MIHAI-DOREL JURCHESCU

    2010-01-01

    Full Text Available Given Romania's integration into the European Union we consider it appropriate to clarify some terms used in auditing activities of both public funds and European funds. International practice requires a clear separation of internal audit activities from other management control concepts and recommend to establish an internal controlling system as well as an internal audit structure under the coordination of the manager as being the only ways cap able to respond to current risks faced by public entities. Internal Audit, along its evolution - characterized by complex dynamics and adaptability - created confusion regarding the concept of control. The research presented in this paper is based on works published to date regarding the conceptual boundaries of this notion.

  6. Damping torque analysis for DC bus implemented damping control

    OpenAIRE

    W. Du; WANG, HAIFENG; Ju, P.; Dunn, R

    2010-01-01

    Damping torque analysis is a well-developed technique for understanding and studying power system oscillations. This paper presents the applications of damping torque analysis for DC bus implemented damping control in power transmission networks in two examples. The first example is the investigation of damping effect of shunt VSC (Voltage Source Converter) based FACTS voltage control, i.e., STATCOM (Static Synchronous Compensator) voltage control. It is shown in the paper that STATCOM voltag...

  7. Solar Dynamic Power System Stability Analysis and Control

    Science.gov (United States)

    Momoh, James A.; Wang, Yanchun

    1996-01-01

    The objective of this research is to conduct dynamic analysis, control design, and control performance test of solar power system. Solar power system consists of generation system and distribution network system. A bench mark system is used in this research, which includes a generator with excitation system and governor, an ac/dc converter, six DDCU's and forty-eight loads. A detailed model is used for modeling generator. Excitation system is represented by a third order model. DDCU is represented by a seventh order system. The load is modeled by the combination of constant power and constant impedance. Eigen-analysis and eigen-sensitivity analysis are used for system dynamic analysis. The effects of excitation system, governor, ac/dc converter control, and the type of load on system stability are discussed. In order to improve system transient stability, nonlinear ac/dc converter control is introduced. The direct linearization method is used for control design. The dynamic analysis results show that these controls affect system stability in different ways. The parameter coordination of controllers are recommended based on the dynamic analysis. It is concluded from the present studies that system stability is improved by the coordination of control parameters and the nonlinear ac/dc converter control stabilize system oscillation caused by the load change and system fault efficiently.

  8. Uncertainty analysis of weather controlled systems

    NARCIS (Netherlands)

    Keesman, K.J.; Doeswijk, T.G.

    2010-01-01

    The indoor climate of many storage facilities for agricultural produce is controlled by mixing ambient air with the air flow through the store room. Hence, the indoor climate is affected by the ambient weather conditions. Given hourly fluctuating energy tariffs, weather forecasts over some days are

  9. Time Series Analysis Forecasting and Control

    CERN Document Server

    Box, George E P; Reinsel, Gregory C

    2011-01-01

    A modernized new edition of one of the most trusted books on time series analysis. Since publication of the first edition in 1970, Time Series Analysis has served as one of the most influential and prominent works on the subject. This new edition maintains its balanced presentation of the tools for modeling and analyzing time series and also introduces the latest developments that have occurred n the field over the past decade through applications from areas such as business, finance, and engineering. The Fourth Edition provides a clearly written exploration of the key methods for building, cl

  10. Analysis of Reconfigured Control Loop with a Virtual Actuator

    Directory of Open Access Journals (Sweden)

    Anna Filasova

    2011-01-01

    Full Text Available Control reconfiguration changes the control structure in response to a fault detected in the plant. This becomes necessary, because a major fault like loss of an actuator breaks the corresponding control loop and therefore renders the whole system inoperable.  An important aim of control reconfiguration is to change the control structure as little as possible, since every change bears the potential of practical problems. The proposed solution is to keep the original controller in the loop and to add an extension called virtual actuator that implements the necessary changes of the control structure. The virtual actuator translates between the signals of the nominal controller and the signal of the faulty plants. This paper is concerned with the analysis of reconfigured loop with a virtual actuator for the system with the faulty actuator. The proposed analysis is illustrated on numerical example.

  11. Nonlinear analysis and control of a continuous fermentation process

    DEFF Research Database (Denmark)

    Szederkényi, G.; Kristensen, Niels Rode; Hangos, K.M;

    2002-01-01

    Different types of nonlinear controllers are designed and compared for a simple continuous bioreactor operating near optimal productivity. This operating point is located close to a fold bifurcation point. Nonlinear analysis of stability, controllability and zero dynamics is used to investigate...... are recommended for the simple fermenter. Passivity based controllers have been found to be globally stable, not very sensitive to the uncertainties in the reaction rate and controller parameter but they require full nonlinear state feedback....

  12. Integration of Design and Control through Model Analysis

    DEFF Research Database (Denmark)

    Russel, Boris Mariboe; Henriksen, Jens Peter; Jørgensen, Sten Bay;

    2002-01-01

    A systematic computer aided analysis of the process model is proposed as a pre-solution step for integration of design and control problems. The process model equations are classified in terms of balance equations, constitutive equations and conditional equations. Analysis of the phenomena models...... representing the constitutive equations identify the relationships between the important process and design variables, which help to understand, define and address some of the issues related to integration of design and control. Furthermore, the analysis is able to identify a set of process (control) variables...... and design (manipulative) variables that may be employed with different objectives in design and control for the integrated problem. The computer aided model analysis is highlighted through illustrative examples, involving processes with mass and/or energy recycle, where the important design and control...

  13. Pushdown Control-Flow Analysis of Higher-Order Programs

    CERN Document Server

    Earl, Christopher; Van Horn, David

    2010-01-01

    Context-free approaches to static analysis gain precision over classical approaches by perfectly matching returns to call sites---a property that eliminates spurious interprocedural paths. Vardoulakis and Shivers's recent formulation of CFA2 showed that it is possible (if expensive) to apply context-free methods to higher-order languages and gain the same boost in precision achieved over first-order programs. To this young body of work on context-free analysis of higher-order programs, we contribute a pushdown control-flow analysis framework, which we derive as an abstract interpretation of a CESK machine with an unbounded stack. One instantiation of this framework marks the first polyvariant pushdown analysis of higher-order programs; another marks the first polynomial-time analysis. In the end, we arrive at a framework for control-flow analysis that can efficiently compute pushdown generalizations of classical control-flow analyses.

  14. Measurement control workshop instructional materials

    Energy Technology Data Exchange (ETDEWEB)

    Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Harvel, Charles [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Clark, John [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gregg Protection Services, Lynchburg, VA (United States)

    2012-09-01

    An essential element in an effective nuclear materials control and accountability (MC&A) program is the measurement of the nuclear material as it is received, moved, processed and shipped. Quality measurement systems and methodologies determine the accuracy of the accountability values. Implementation of a measurement control program is essential to ensure that the measurement systems and methodologies perform as expected. A measurement control program also allows for a determination of the level of confidence in the accounting values.

  15. Measurement control workshop instructional materials

    Energy Technology Data Exchange (ETDEWEB)

    Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Harvel, Charles [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Clark, John [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gregg Protection Services, Lynchburg, VA (United States)

    2011-12-01

    An essential element in an effective nuclear materials control and accountability (MC&A) program is the measurement of the nuclear material as it is received, moved, processed and shipped. Quality measurement systems and methodologies determine the accuracy of the accountability values. Implementation of a measurement control program is essential to ensure that the measurement systems and methodologies perform as expected. A measurement control program also allows for a determination of the level of confidence in the ac counting values.

  16. Analysis and design of networked control systems

    CERN Document Server

    You, Keyou; Xie, Lihua

    2015-01-01

    This monograph focuses on characterizing the stability and performance consequences of inserting limited-capacity communication networks within a control loop. The text shows how integration of the ideas of control and estimation with those of communication and information theory can be used to provide important insights concerning several fundamental problems such as: ·         minimum data rate for stabilization of linear systems over noisy channels; ·         minimum network requirement for stabilization of linear systems over fading channels; and ·         stability of Kalman filtering with intermittent observations. A fundamental link is revealed between the topological entropy of linear dynamical systems and the capacities of communication channels. The design of a logarithmic quantizer for the stabilization of linear systems under various network environments is also extensively discussed and solutions to many problems of Kalman filtering with intermittent observations are de...

  17. Controllability analysis of modified Petlyuk structures

    Energy Technology Data Exchange (ETDEWEB)

    Tamayo-Galvan, V.E.; Segovia-Hernandez, J.G.; Hernandez, S.; Hernandez, H. [Guanajuato Univ. (Mexico). Faculty of Chemistry

    2008-02-15

    Distillation columns can consume a large portion of energy in chemical industry processes. Integrated Petlyuk columns have been shown to improve energy efficiencies by between 20 and 40 per cent, and thermally coupled distillation columns can serve as an alternative to conventional distillation sequences in multicomponent mixture separation processes. Until recently, operational difficulties have limited the wider introduction of Petlyuk columns in industrial applications. Alternative Petlyuk-type schemes have now been developed to provide improved operation properties. This paper discussed, evaluated, and compared the theoretical control properties of 6 different Petlyuk schemes. Computations were performed using a singular value decomposition (SVD) technique in the frequency domain. Dynamic closed-loop responses for set point tracking, and disturbance rejections were derived in order to support each scheme's theoretical control properties. Results of the comparative evaluation demonstrated that reductions in the number of interconnections and the use of unidirectional flows impacted the dynamic properties of the schemes, and led to operational improvements in thermally coupled distillation sequences. It was concluded that Petyluk properties can be improved through the correction of the bidirectionality of interconnecting streams. 30 refs., 10 tabs., 9 figs.

  18. Complexity, Analysis and Control of Singular Biological Systems

    CERN Document Server

    Zhang, Qingling; Zhang, Xue

    2012-01-01

    Complexity, Analysis and Control of Singular Biological Systems follows the control of real-world biological systems at both ecological and phyisological levels concentrating on the application of now-extensively-investigated singular system theory. Much effort has recently been dedicated to the modelling and analysis of developing bioeconomic systems and the text establishes singular examples of these, showing how proper control can help to maintain sustainable economic development of biological resources. The book begins from the essentials of singular systems theory and bifurcations before tackling  the use of various forms of control in singular biological systems using examples including predator-prey relationships and viral vaccination and quarantine control. Researchers and graduate students studying the control of complex biological systems are shown how a variety of methods can be brought to bear and practitioners working with the economics of biological systems and their control will also find the ...

  19. Discrete Mechanics and Optimal Control: an Analysis

    CERN Document Server

    Ober-Bloebaum, S; Marsden, J E

    2008-01-01

    The optimal control of a mechanical system is of crucial importance in many realms. Typical examples are the determination of a time-minimal path in vehicle dynamics, a minimal energy trajectory in space mission design, or optimal motion sequences in robotics and biomechanics. In most cases, some sort of discretization of the original, infinite-dimensional optimization problem has to be performed in order to make the problem amenable to computations. The approach proposed in this paper is to directly discretize the variational description of the system's motion. The resulting optimization algorithm lets the discrete solution directly inherit characteristic structural properties from the continuous one like symmetries and integrals of the motion. We show that the DMOC approach is equivalent to a finite difference discretization of Hamilton's equations by a symplectic partitioned Runge-Kutta scheme and employ this fact in order to give a proof of convergence. The numerical performance of DMOC and its relationsh...

  20. Control and Analysis of Droop and Reverse Droop Controllers for Distributed Generations

    DEFF Research Database (Denmark)

    Wu, Dan; Tang, Fen; Vasquez, Juan Carlos;

    2014-01-01

    This paper addresses control and analysis of droop and reverse droop control for distributed generations (DG). The droop control is well known applied to the voltage control mode (VCM) DG units, but has limitation when implemented on the current control mode (CCM) units. Therefore, this paper gives...... a more complete primary control for DG systems that integrates with both VCM and CCM units. The power management can be uniformly achieved by designing proportional droop and reverse droop parameters. And the power sharing effect among CCM and VCM DG units is discussed. Finally, hardware...

  1. Radial Clearance Control and Internal Leakage Analysis of a Tri-Proportion Controller

    Institute of Scientific and Technical Information of China (English)

    LI Dai-jin; ZHANG Yu-wen; TANG Hao; DANG Jian-jun; LUO Kai

    2009-01-01

    The tri-propellant thermal propulsion system is one of the hottest subjects in the.field of underwater vehicles recently. To improve efficiency of underwater vehicles, a method of radial clearance control of the tri-proportion has been proposed. Based on analyzing the factors which influence the pressure decrease and leakage of the tri-proportion controller, a method is used for precision analysis and proportion adjustment by using the median optimizing theory. Analysis results show that accuracy of the proportion controller is dependent on all the leakage, while the leakage is decided by radial clearance and pressure; the leakage can be controlled effectively and the accuracy of the proportion can be improved with the radial clearance control method. The method of accuracy analysis and clearance control has value on the design of various hydraulic motors.

  2. Experimental Bifurcation Analysis Using Control-Based Continuation

    DEFF Research Database (Denmark)

    Bureau, Emil; Starke, Jens

    The focus of this thesis is developing and implementing techniques for performing experimental bifurcation analysis on nonlinear mechanical systems. The research centers around the newly developed control-based continuation method, which allows to systematically track branches of stable and unsta......The focus of this thesis is developing and implementing techniques for performing experimental bifurcation analysis on nonlinear mechanical systems. The research centers around the newly developed control-based continuation method, which allows to systematically track branches of stable...

  3. Pressure Control in Distillation Columns: A Model-Based Analysis

    DEFF Research Database (Denmark)

    Mauricio Iglesias, Miguel; Bisgaard, Thomas; Kristensen, Henrik;

    2014-01-01

    A comprehensive assessment of pressure control in distillation columns is presented, including the consequences for composition control and energy consumption. Two types of representative control structures are modeled, analyzed, and benchmarked. A detailed simulation test, based on a real...... industrial distillation column, is used to assess the differences between the two control structures and to demonstrate the benefits of pressure control in the operation. In the second part of the article, a thermodynamic analysis is carried out to establish the influence of pressure on relative volatility...

  4. Analysis and Design of PLL Motor Speed Control System

    Directory of Open Access Journals (Sweden)

    Qi Chao Zhang

    2013-10-01

    Full Text Available Phase-locked technology in motor speed control system has a wide range of applications, Especially for high accuracy in the motor steady speed operation situation, more and more use of phase-locked servo control system. This paper describes the block diagram and mathematical model of phase-locked control system, Shows the circuit parameter calculation method This and combined with design example analysis of phase-locked control system, Indicated through the theory and practice, using PLL can obtain good speed control precision.

  5. Multi-dimensional project evaluation: Combining cost-benefit analysis and multi-criteria analysis with the COSIMA software system

    DEFF Research Database (Denmark)

    This paper proposes a methodology that integrates quantitative and qualitative assessment. The methodology proposed combines conventional cost-benefit analysis (CBA) with multi-criteria analysis (MCA). The CBA methodology, based on welfare theory, assures that the project with the highest welfare...... different methods for combining cost-benefit analysis and multi-criteria analysis are examined and compared and a software system is presented. The software system gives the decision makers some possibilities regarding preference analysis, sensitivity and risk analysis. The aim of the software...... and software system for CBA and MCA decision making is finally compared with other methods for combining the CBA and MCA. Ultimately, some conclusions are made and perspectives are drawn. Keywords: Cost-benefit analysis, Multi-criteria analysis, Multiple Criteria Decision Aiding, Transport infrastructure...

  6. Aircraft Accident Prevention: Loss-of-Control Analysis

    Science.gov (United States)

    Kwatny, Harry G.; Dongmo, Jean-Etienne T.; Chang, Bor-Chin; Bajpai, Guarav; Yasar, Murat; Belcastro, Christine M.

    2009-01-01

    The majority of fatal aircraft accidents are associated with loss-of-control . Yet the notion of loss-of-control is not well-defined in terms suitable for rigorous control systems analysis. Loss-of-control is generally associated with flight outside of the normal flight envelope, with nonlinear influences, and with an inability of the pilot to control the aircraft. The two primary sources of nonlinearity are the intrinsic nonlinear dynamics of the aircraft and the state and control constraints within which the aircraft must operate. In this paper we examine how these nonlinearities affect the ability to control the aircraft and how they may contribute to loss-of-control. Examples are provided using NASA s Generic Transport Model.

  7. Updated Meta-Analysis of Learner Control within Educational Technology

    Science.gov (United States)

    Karich, Abbey C.; Burns, Matthew K.; Maki, Kathrin E.

    2014-01-01

    Giving a student control over their learning has theoretical and intuitive appeal, but its effects are neither powerful nor consistent in the empirical literature base. This meta-analysis updated previous meta-analytic research by Niemiec, Sikorski, and Walberg by studying the overall effectiveness of providing learner control within educational…

  8. Regulatory control analysis and design for sewer systems

    DEFF Research Database (Denmark)

    Mollerup, Ane Loft; Mikkelsen, Peter Steen; Thornberg, Dines;

    2015-01-01

    case study area of Copenhagen. The analysis effectively reduces the number of potential controlled variables, by considering the sensitivity of the measurements towards changes in the manipulated variables. Several potential pairings are generated and the best alternative is chosen for closed......-loop testing. The methodology is a promising tool for systematic generation of solutions for sewer system control....

  9. Analysis of supplementary controls in damping subsynchronous oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Balasubramanyam, P.V.; Murty, A.S.R.; Sarkar, B.N. [Central Power Research Inst., Bangalore (India). Central Research and Testing Lab.

    1995-12-31

    Analysis and damping of torsional oscillations through thyristor control reactor (TCR) is presented in this paper. The reactive power control is achieved through TCR at the machine terminals. Generator speed deviation signal is used as auxiliary signal and terminal voltage feed back signal as main control signal for TCR. The following control strategies for auxiliary control to TCR have been analyzed. Case 1: Analysis of basic system without damping controls. Case 2: Proportional control (P). Case 3: Proportional control with filter (P+filter). Case 4: Proportional plus derivative control with filter (P+D+filter). Case 5: Proportional plus integral plus derivative control with filter (P+I+D+filter). The main objective of this paper is to discuss the performance of different control strategies for damping torsional oscillations when a generator is connected to an infinite bus via double circuit 400kV transmission line, in which one circuit is series compensated. This configuration is similar to IEEE benchmark two model.

  10. Power system small signal stability analysis and control

    CERN Document Server

    Mondal, Debasish; Sengupta, Aparajita

    2014-01-01

    Power System Small Signal Stability Analysis and Control presents a detailed analysis of the problem of severe outages due to the sustained growth of small signal oscillations in modern interconnected power systems. The ever-expanding nature of power systems and the rapid upgrade to smart grid technologies call for the implementation of robust and optimal controls. Power systems that are forced to operate close to their stability limit have resulted in the use of control devices by utility companies to improve the performance of the transmission system against commonly occurring power system

  11. Control design and analysis for underactuated robotic systems

    CERN Document Server

    Xin, Xin

    2014-01-01

    The last two decades have witnessed considerable progress in the study of underactuated robotic systems (URSs). Control Design and Analysis for Underactuated Robotic Systems presents a unified treatment of control design and analysis for a class of URSs, which include systems with multiple-degree-of-freedom and/or with underactuation degree two. It presents novel notions, features, design techniques, and strictly global motion analysis results for these systems. These new materials are shown to be vital in studying the control design and stability analysis of URSs. Control Design and Analysis for Underactuated Robotic Systems includes the modelling, control design, and analysis presented in a systematic way particularly for the following examples: l  directly and remotely driven  Acrobots l  Pendubot l  rotational pendulum l  counter-weighted Acrobot 2-link underactuated robot with flexible elbow joint l  variable-length pendulum l  3-link gymnastic robot with passive first joint l  n-link planar robo...

  12. Analysis and design of robust decentralized controllers for nonlinear systems

    Energy Technology Data Exchange (ETDEWEB)

    Schoenwald, D.A.

    1993-07-01

    Decentralized control strategies for nonlinear systems are achieved via feedback linearization techniques. New results on optimization and parameter robustness of non-linear systems are also developed. In addition, parametric uncertainty in large-scale systems is handled by sensitivity analysis and optimal control methods in a completely decentralized framework. This idea is applied to alleviate uncertainty in friction parameters for the gimbal joints on Space Station Freedom. As an example of decentralized nonlinear control, singular perturbation methods and distributed vibration damping are merged into a control strategy for a two-link flexible manipulator.

  13. Task analysis methods applicable to control room design review (CDR)

    International Nuclear Information System (INIS)

    This report presents the results of a research study conducted in support of the human factors engineering program of the Atomic Energy Control Board in Canada. It contains five products which may be used by the Atomic Enegy Control Board in relation to Task Analysis of jobs in CANDU nuclear power plants: 1. a detailed method for preparing for a task analysis; 2. a Task Data Form for recording task analysis data; 3. a detailed method for carrying out task analyses; 4. a guide to assessing alternative methods for performing task analyses, if such are proposed by utilities or consultants; and 5. an annotated bibliography on task analysis. In addition, a short explanation of the origins, nature and uses of task analysis is provided, with some examples of its cost effectiveness. 35 refs

  14. REVIEW OF NRC APPROVED DIGITAL CONTROL SYSTEMS ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    D.W. Markman

    1999-09-17

    Preliminary design concepts for the proposed Subsurface Repository at Yucca Mountain indicate extensive reliance on modern, computer-based, digital control technologies. The purpose of this analysis is to investigate the degree to which the U. S. Nuclear Regulatory Commission (NRC) has accepted and approved the use of digital control technology for safety-related applications within the nuclear power industry. This analysis reviews cases of existing digitally-based control systems that have been approved by the NRC. These cases can serve as precedence for using similar types of digitally-based control technologies within the Subsurface Repository. While it is anticipated that the Yucca Mountain Project (YMP) will not contain control systems as complex as those required for a nuclear power plant, the review of these existing NRC approved applications will provide the YMP with valuable insight into the NRCs review process and design expectations for safety-related digital control systems. According to the YMP Compliance Program Guidance, portions of various NUREGS, Regulatory Guidelines, and nuclear IEEE standards the nuclear power plant safety related concept would be applied to some of the designs on a case-by-case basis. This analysis will consider key design methods, capabilities, successes, and important limitations or problems of selected control systems that have been approved for use in the Nuclear Power industry. An additional purpose of this analysis is to provide background information in support of further development of design criteria for the YMP. The scope and primary objectives of this analysis are to: (1) Identify and research the extent and precedence of digital control and remotely operated systems approved by the NRC for the nuclear power industry. Help provide a basis for using and relying on digital technologies for nuclear related safety critical applications. (2) Identify the basic control architecture and methods of key digital control

  15. REVIEW OF NRC APPROVED DIGITAL CONTROL SYSTEMS ANALYSIS

    International Nuclear Information System (INIS)

    Preliminary design concepts for the proposed Subsurface Repository at Yucca Mountain indicate extensive reliance on modern, computer-based, digital control technologies. The purpose of this analysis is to investigate the degree to which the U. S. Nuclear Regulatory Commission (NRC) has accepted and approved the use of digital control technology for safety-related applications within the nuclear power industry. This analysis reviews cases of existing digitally-based control systems that have been approved by the NRC. These cases can serve as precedence for using similar types of digitally-based control technologies within the Subsurface Repository. While it is anticipated that the Yucca Mountain Project (YMP) will not contain control systems as complex as those required for a nuclear power plant, the review of these existing NRC approved applications will provide the YMP with valuable insight into the NRCs review process and design expectations for safety-related digital control systems. According to the YMP Compliance Program Guidance, portions of various NUREGS, Regulatory Guidelines, and nuclear IEEE standards the nuclear power plant safety related concept would be applied to some of the designs on a case-by-case basis. This analysis will consider key design methods, capabilities, successes, and important limitations or problems of selected control systems that have been approved for use in the Nuclear Power industry. An additional purpose of this analysis is to provide background information in support of further development of design criteria for the YMP. The scope and primary objectives of this analysis are to: (1) Identify and research the extent and precedence of digital control and remotely operated systems approved by the NRC for the nuclear power industry. Help provide a basis for using and relying on digital technologies for nuclear related safety critical applications. (2) Identify the basic control architecture and methods of key digital control

  16. Developing standard performance testing procedures for material control and accounting components at a site

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, Carolynn P [Los Alamos National Laboratory; Bushlya, Anatoly V [ROSATOM, RUSSIA; Efimenko, Vladimir F [IPPE, RUSSIA; Ilyanstev, Anatoly [IPPE, RUSSIA; Regoushevsky, Victor I [IPPE, RUSSIA

    2010-01-01

    The condition of a nuclear material control and accountability system (MC&A) and its individual components, as with any system combining technical elements and documentation, may be characterized through an aggregate of values for the various parameters that determine the system's ability to perform. The MC&A system's status may be functioning effectively, marginally or not functioning based on a summary of the values of the individual parameters. This work included a review of the following subsystems, MC&A and Detecting Material Losses, and their respective elements for the material control and accountability system: (a) Elements of the MC&A Subsystem - Information subsystem (Accountancy/Inventory), Measurement subsystem, Nuclear Material Access subsystem, including tamper-indicating device (TID) program, and Automated Information-gathering subsystem; (b) Elements for Detecting Nuclear Material Loses Subsystem - Inventory Differences, Shipper/receiver Differences, Confirmatory Measurements and differences with accounting data, and TID or Seal Violations. In order to detect the absence or loss of nuclear material there must be appropriate interactions among the elements and their respective subsystems from the list above. Additionally this work includes a review of regulatory requirements for the MC&A system component characteristics and criteria that support the evaluation of the performance of the listed components. The listed components had performance testing algorithms and procedures developed that took into consideration the regulatory criteria. The developed MC&A performance-testing procedures were the basis for a Guide for MC&A Performance Testing at the material balance areas (MBAs) of State Scientific Center of the Russian Federation - Institute for Physics and Power Engineering (SSC RF-IPPE).

  17. Quantitative cerebral perfusion assessment using microscope-integrated analysis of intraoperative indocyanine green fluorescence angiography versus positron emission tomography in superficial temporal artery to middle cerebral artery anastomosis

    Directory of Open Access Journals (Sweden)

    Shinya Kobayashi

    2014-01-01

    Full Text Available Background: Intraoperative qualitative indocyanine green (ICG angiography has been used in cerebrovascular surgery. Hyperperfusion may lead to neurological complications after superficial temporal artery to middle cerebral artery (STA-MCA anastomosis. The purpose of this study is to quantitatively evaluate intraoperative cerebral perfusion using microscope-integrated dynamic ICG fluorescence analysis, and to assess whether this value predicts hyperperfusion syndrome (HPS after STA-MCA anastomosis. Methods: Ten patients undergoing STA-MCA anastomosis due to unilateral major cerebral artery occlusive disease were included. Ten patients with normal cerebral perfusion served as controls. The ICG transit curve from six regions of interest (ROIs on the cortex, corresponding to ROIs on positron emission tomography (PET study, was recorded. Maximum intensity (I MAX , cerebral blood flow index (CBFi, rise time (RT, and time to peak (TTP were evaluated. Results: RT/TTP, but not I MAX or CBFi, could differentiate between control and study subjects. RT/TTP correlated (|r| = 0.534-0.807; P < 0.01 with mean transit time (MTT/MTT ratio in the ipsilateral to contralateral hemisphere by PET study. Bland-Altman analysis showed a wide limit of agreement between RT and MTT and between TTP and MTT. The ratio of RT before and after bypass procedures was significantly lower in patients with postoperative HPS than in patients without postoperative HPS (0.60 ± 0.032 and 0.80 ± 0.056, respectively; P = 0.017. The ratio of TTP was also significantly lower in patients with postoperative HPS than in patients without postoperative HPS (0.64 ± 0.081 and 0.85 ± 0.095, respectively; P = 0.017. Conclusions: Time-dependent intraoperative parameters from the ICG transit curve provide quantitative information regarding cerebral circulation time with quality and utility comparable to information obtained by PET. These parameters may help predict the occurrence of postoperative

  18. Predictive PI control and its robust stability analysis

    Institute of Scientific and Technical Information of China (English)

    Ren Zhengyun; Zhang Hong; Shao Huihe

    2005-01-01

    It is difficult to analyze robust BIBO stability of predictive PI (PPI) control system due to the time delay of process. A novel technique for stability analysis of this kind of system is proposed in this paper. The state space form of PPI control system is given, and its characteristic polynomial is derived by a simple method, so the robust BIBO stability analysis of this kind of system is also the analysis of corresponding characteristic polynomial. Applying Kharitonov theorem and edge theorem, the BIBO stability can be judged for arbitrarily given process parameter intervals. The system robust stability with variable process parameters is described respectively, and some beneficial conclusions for the design of PPI controller are obtained.

  19. REACTOR ANALYSIS AND VIRTUAL CONTROL ENVIRONMENT (RAVEN) FY12 REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Cristian Rabiti; Andrea Alfonsi; Joshua Cogliati; Diego Mandelli; Robert Kinoshita

    2012-09-01

    RAVEN is a complex software tool that will have tasks spanning from being the RELAP-7 user interface, to using RELAP-7 to perform Risk Informed Safety Characterization (RISMC), and to controlling RELAP-7 calculation execution. The goal of this document is to: 1. Highlight the functional requirements of the different tasks of RAVEN 2. Identify shared functions that could be aggregate in modules so to obtain a minimal software redundancy and maximize software utilization. RAVEN is in fact a software framework that will allow exploiting the following functionalities: • Derive and actuate the control logic required to: o Simulate the plant control system o Simulate the operator (procedure guided) actions o Perform Monte Carlo sampling of random distributed events o Perform event three based analysis • Provide a GUI to: o Input a plant description to RELAP-7 (component, control variable, control parameters) o Concurrent monitoring of Control Parameters o Concurrent alteration of control parameters • Provide Post Processing data mining capability based on o Dimensionality reduction o Cardinality reduction In this document it will be shown how an appropriate mathematical formulation of the control logic and probabilistic analysis leads to have most of the software infrastructure leveraged between the two main tasks. Further, this document will go through the development accomplished this year, including simulation results, and priorities for the next years development

  20. Sensitivity Analysis and Optimal Control of Anthroponotic Cutaneous Leishmania

    Science.gov (United States)

    Zamir, Muhammad; Zaman, Gul; Alshomrani, Ali Saleh

    2016-01-01

    This paper is focused on the transmission dynamics and optimal control of Anthroponotic Cutaneous Leishmania. The threshold condition R0 for initial transmission of infection is obtained by next generation method. Biological sense of the threshold condition is investigated and discussed in detail. The sensitivity analysis of the reproduction number is presented and the most sensitive parameters are high lighted. On the basis of sensitivity analysis, some control strategies are introduced in the model. These strategies positively reduce the effect of the parameters with high sensitivity indices, on the initial transmission. Finally, an optimal control strategy is presented by taking into account the cost associated with control strategies. It is also shown that an optimal control exists for the proposed control problem. The goal of optimal control problem is to minimize, the cost associated with control strategies and the chances of infectious humans, exposed humans and vector population to become infected. Numerical simulations are carried out with the help of Runge-Kutta fourth order procedure. PMID:27505634

  1. QUALITY CONTROL OF SEMICONDUCTOR PACKAGING BASED ON PRINCIPAL COMPONENTS ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    5 critical quality characteristics must be controlled in the surface mount and wire-bond process in semiconductor packaging. And these characteristics are correlated with each other. So the principal components analysis(PCA) is used in the analysis of the sample data firstly. And then the process is controlled with hotelling T2 control chart for the first several principal components which contain sufficient information. Furthermore, a software tool is developed for this kind of problems. And with sample data from a surface mounting device(SMD) process, it is demonstrated that the T2 control chart with PCA gets the same conclusion as without PCA, but the problem is transformed from high-dimensional one to a lower dimensional one, i.e., from 5 to 2 in this demonstration.

  2. Control of directed cell migration in vivo by membrane-to-cortex attachment.

    Directory of Open Access Journals (Sweden)

    Alba Diz-Muñoz

    Full Text Available Cell shape and motility are primarily controlled by cellular mechanics. The attachment of the plasma membrane to the underlying actomyosin cortex has been proposed to be important for cellular processes involving membrane deformation. However, little is known about the actual function of membrane-to-cortex attachment (MCA in cell protrusion formation and migration, in particular in the context of the developing embryo. Here, we use a multidisciplinary approach to study MCA in zebrafish mesoderm and endoderm (mesendoderm germ layer progenitor cells, which migrate using a combination of different protrusion types, namely, lamellipodia, filopodia, and blebs, during zebrafish gastrulation. By interfering with the activity of molecules linking the cortex to the membrane and measuring resulting changes in MCA by atomic force microscopy, we show that reducing MCA in mesendoderm progenitors increases the proportion of cellular blebs and reduces the directionality of cell migration. We propose that MCA is a key parameter controlling the relative proportions of different cell protrusion types in mesendoderm progenitors, and thus is key in controlling directed migration during gastrulation.

  3. Facilitator control as automatic behavior: A verbal behavior analysis

    OpenAIRE

    Hall, Genae A.

    1993-01-01

    Several studies of facilitated communication have demonstrated that the facilitators were controlling and directing the typing, although they appeared to be unaware of doing so. Such results shift the focus of analysis to the facilitator's behavior and raise questions regarding the controlling variables for that behavior. This paper analyzes facilitator behavior as an instance of automatic verbal behavior, from the perspective of Skinner's (1957) book Verbal Behavior. Verbal behavior is autom...

  4. Tobacco control in the Russian Federation- a policy analysis

    OpenAIRE

    Lunze, Karsten; Migliorini, Luigi

    2013-01-01

    Background The Russian Federation (Russia) has one of the highest smoking rates in the world. The purpose of this study is to analyze past and current trends of the tobacco epidemic in the Russian Federation, review current tobacco control policy responses, and identify areas of opportunity for policy priorities. Methods We used a policy triangle as analytical framework to examine content, context, and processes of Russian tobacco control policy. The analysis was based on secondary data on su...

  5. Dynamics and control: energy conversion, delivery, and demand analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, K.C.

    1979-04-01

    Techniques of mathematical modeling and modern control theory, using microprocessors and advanced measurement and control devices, are extensively applied to components and systems for the conversion and delivery of energy. The projection of energy demands, as a function of economic growth and energy price, is also the subject of active research and analysis. This position paper reviews the current state-of-the-art of analysis in these areas dealing with the planning and operation of energy systems that deliver fuels and electric power. Future research directions are also discussed. 25 references.

  6. Motion analysis and remote control system using pyroelectric infrared sensors

    OpenAIRE

    Fuksis, R.; Greitans, M.; Hermanis, E.

    2008-01-01

    The paper discusses the possibilities of exploiting infrared radiation for motion analysis and remote control. The human body is considered as the information source and dual-element pyroelectric infrared (PIR) detectors as the sensor system. A dual-element sensor allows the analysis of the motion of objects in one-dimension, therefore it is proposed to place two sensors perpendicularly. Such a method provides the capability of distinguishing eight different commands. An experimental set-up h...

  7. Control capability analysis for complex spacecraft thruster configurations

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The set of forces and moments that can be generated by thrusters of a spacecraft is called the"control capability"with respect to the thruster configuration.If the control capability of a thruster configuration is adequate to fulfill a given space mission,we say this configuration is a feasible one with respect to the task.This study proposed a new way to analyze the control capability of the complex thruster configuration.Precise mathematical definitions of feasibility were proposed,based on which a criterion to judge the feasibility of the thruster configuration was presented through calculating the shortest distance to the boundary of the controllable region as a function of the thruster configuration.Finally,control capability analysis for the complex thruster configuration based on its feasibility with respect to the space mission was given followed by a 2-D thruster configuration example to demonstrate its validity.

  8. Stability Analysis on Speed Control System of Autonomous Underwater Vehicle

    Institute of Scientific and Technical Information of China (English)

    LI Ye; PANG Yong-jie; WAN Lei; WANG Fang; LIAO Yu-lei

    2009-01-01

    The stability of the motion control system is one of the decisive factors of the control quality for Autonomous Underwater Vehicle (AUV).The divergence of control,which the unstable system may be brought about,is fatal to the operation of AUV.The stability analysis of the PD and S-surface speed controllers based on the Lyapunov' s direct method is proposed in this paper.After decoupling the six degree-of-freedom (DOF) motions of the AUV,the axial dynamic behavior is discussed and the condition is deduced,in which the parameters selection within stability domain can guarantee the system asymptotically stable.The experimental results in a tank and on the sea have successfully verified the algorithm reliability,which can be served as a good reference for analyzing other AUV nonlinear control systems.

  9. Control Flow Analysis for the Pi-calculus

    DEFF Research Database (Denmark)

    Bodei, C.; Degano, P.; Nielson, Flemming;

    1998-01-01

    Control Flow Analysis is a static technique for predicting safe and computable approximations to the set of values that the objects of a program may assume during its execution. We present an analysis for the pi-calculus that shows how names will be bound to actual channels at run time. The formu......Control Flow Analysis is a static technique for predicting safe and computable approximations to the set of values that the objects of a program may assume during its execution. We present an analysis for the pi-calculus that shows how names will be bound to actual channels at run time....... The formulation of the analysis requires no extensions to the pi-calculus, except for assigning ``channels'' to the occurrences of names within restrictions, and assigning ``binders'' to the occurrences of names within input prefixes. The result of our analysis establishes a super-set of the set of names to which...... a given name may be bound and of the set of names that may be sent along a given channel. Applications of our analysis include establishing simple security properties of processes. One example is that P has no leaks, i.e. P offers communication through public channels only, and confines its secret names...

  10. Control Flow Analysis Can Find New Flaws Too

    DEFF Research Database (Denmark)

    Bodei, Chiara; Buchholtz, Mikael; Degano, Pierpaolo;

    2004-01-01

    A previous study showed how control flow analysis can be applied to analyse key distribution protocols based on symmetric key cryptography. We have extended both the theoretical treatment and our fully automatic verifier to deal with protocols based on asymmetric cryptography. This paper reports...

  11. Multilayer FeRh/MgO: controllable magnetocrystalline anisotropy for an antiferromagnetic system

    Science.gov (United States)

    Zheng, Guohui; Dorj, Odkhuu; Ke, Sanhuang; Ramesh, Rammoorthy; Miao, Maosheng; Kioussis, Nickolas

    2015-03-01

    Controlling the magnetocrystalline anisotropy (MCA) of ferromagnetic (FM) thin films by tunable strain and electric field has been pursued as an effective method of achieving low-power and highly scalable memory. Comparing with FM materials, AFM are much less sensitive to external magnetic field, a substantial advantage for memory devices. Inspired by recent work on AFM memory resistors based on FeRh, we carried out a systematic first principles study of the MCA of multi-layer FeRh, either stand alone, or combined with MgO layers. FeRh is a unique material that undergoes a transition from AFM (type-II) to FM at elevated temperature of 370 K. Our calculations for thin films of FeRh from 5-15 atomic layers reveal that AFM is always the most stable configuration for Fe terminated films; while for Rh terminated films, there is a transition from FM to a configuration featured AFM at the center layers and FM at the surface layers (reconstructed). While applying the spin-orbit interactions (SOI) for the valence electrons, we found Fe-terminated films exhibit a relatively small MCA that varies and may change sign with film thickness, substrate and strain, providing a possibility of spin reorientation via the control of strain and electric field. The k-resolved MCA values reveals that the region around Gamma point adds the major contribution to the MCA.

  12. Chaos in electric drive systems analysis control and application

    CERN Document Server

    Chau, K T

    2011-01-01

    In Chaos in Electric Drive Systems: Analysis, Control and Application authors Chau and Wang systematically introduce an emerging technology of electrical engineering that bridges abstract chaos theory and practical electric drives. The authors consolidate all important information in this interdisciplinary technology, including the fundamental concepts, mathematical modeling, theoretical analysis, computer simulation, and hardware implementation. The book provides comprehensive coverage of chaos in electric drive systems with three main parts: analysis, control and application. Corresponding drive systems range from the simplest to the latest types: DC, induction, synchronous reluctance, switched reluctance, and permanent magnet brushless drives.The first book to comprehensively treat chaos in electric drive systemsReviews chaos in various electrical engineering technologies and drive systemsPresents innovative approaches to stabilize and stimulate chaos in typical drivesDiscusses practical application of cha...

  13. Cost/benefit analysis of eliminating poison control in LWRs

    International Nuclear Information System (INIS)

    Since the economics of power generation determines, to a large extent,a utility's choice of reactor systems, the cost of electricity from a spectral shift control (SSC) reactor is a crucial measure of the SSC reactor's competitiveness. Thus, a preliminary cost analysis is an important part of our overall assessment. The economic comparisons in this work focus on the cost differences between a standard pressurized water reactor (PWR) and the breeder/moderator controlled/burner light water reactor (BMB-LWR) design concept. The BMB-LWR is a typical large current design PWR with a minimum of changes. The BMB-LWR does not use any poison for reactivity control in the cycle length range of interest (1 to 2 yr) and uses soluble poison only for refueling purposes, to provide a sufficient additional negative reactivity margin to supplement the water displacement system. However, the water displacement system is very similar to the control rod system from a mechanical design point of view, differing mainly in the characteristics of the in-core control pins. Mixing both poison and displacer pins in the same core introduces added complexity, but not necessarily at a large cost impact; e.g., the advanced PWR has substantial water displacement control components, whereas the BMB-LWR primarily increases the displacer-to-poison ratio. The annual credits and penalties of replacing the standard PWR with the BMB-LWR concept are covered in the analysis

  14. Harmoniousness analysis of total amount control of water use

    Institute of Scientific and Technical Information of China (English)

    Qian-qi YIN; Guo-hua FANG

    2014-01-01

    Based on the fundamental principles of total amount control of water use, the harmony theory was used in this study to develop a concept of the degree of harmony of total amount control of water use. Based on this concept, the harmoniousness of total amount control of water use was analyzed in terms of the supply and demand of water resources, water resources management, water use benefits, and water-saving level. An evaluation index system of the degree of harmony of total amount control of water use was established, and a method for calculation of the degree of harmony of total amount control of water use was developed based on the analytic hierarchy process (AHP) and fuzzy comprehensive analysis (FCA) methods. The new evaluation index system was applied to a certain area in Jiangsu Province, China. The degree of harmony of total amount control of water use over this area was calculated for different years. Results indicate that the evaluation index system and calculation method proposed in this study are feasible, and such a harmoniousness analysis can provide scientific references for the strict water resources management system that will be implemented in China in the near future.

  15. Cooperative efforts of the materials protection control and accounting program at the electrochemical plant (Krasnoyarsk-45) in Russia-011

    Energy Technology Data Exchange (ETDEWEB)

    Moore, L.

    1998-07-22

    The USDOE Material Protection Control and Accountability Program (MPC&A) has established a Project Team with the goal of providing the Russian Electrochemical Plant (ECP) with equipment and training to enable ECP to evaluate, develop, and implement a comprehensive plan and systems for physical protection, material controls, and accountancy upgrades. The MPC&A project will provide for improvements such as risk assessments, access control upgrades, computerized MC&A, communications systems upgrades, building perimeter surveillance and intrusion detection upgrades, vault upgrades, metal and nuclear material detection upgrades, along with mass measurement and non- destructive analysis (NDA) instrumentation. This paper outlines the overall objectives of the MPC&A project at the Electrochemical Plant.

  16. Preliminary control system design and analysis for the Space Station Furnace Facility thermal control system

    Science.gov (United States)

    Jackson, M. E.

    1995-01-01

    This report presents the Space Station Furnace Facility (SSFF) thermal control system (TCS) preliminary control system design and analysis. The SSFF provides the necessary core systems to operate various materials processing furnaces. The TCS is defined as one of the core systems, and its function is to collect excess heat from furnaces and to provide precise cold temperature control of components and of certain furnace zones. Physical interconnection of parallel thermal control subsystems through a common pump implies the description of the TCS by coupled nonlinear differential equations in pressure and flow. This report formulates the system equations and develops the controllers that cause the interconnected subsystems to satisfy flow rate tracking requirements. Extensive digital simulation results are presented to show the flow rate tracking performance.

  17. Stability Analysis and Design of Impulsive Control Lorenz Systems Family

    Institute of Scientific and Technical Information of China (English)

    YU Yong-Bin; ZHANG Hong-Bin; ZHANG Feng-Li; YU Jue-Bang; LIAO Xiao-Feng

    2009-01-01

    Lorenz systems family unifying Lorenz system, Chen system and Lu system is a typical chaotic family.In this paper, we consider impulsive control Lorenz chaotic systems family with time-varying impulse intervals. By establishing an effective tool of a set of inequalities, we analyze the asymptotic stability of impulsive control Lorenz systems family and obtain some new less conservative conditions. Based on the stability analysis, we design a novel impulsive controller with time-varying impulse intervals. Illustrative examples are provided to show the feasibility and effectiveness of our method. The obtained results not only can be used to design impulsive control for Lorenz systems family, but also can be extended to other chaotic systems.

  18. Rotor-Flying Manipulator: Modeling, Analysis, and Control

    Directory of Open Access Journals (Sweden)

    Bin Yang

    2014-01-01

    Full Text Available Equipping multijoint manipulators on a mobile robot is a typical redesign scheme to make the latter be able to actively influence the surroundings and has been extensively used for many ground robots, underwater robots, and space robotic systems. However, the rotor-flying robot (RFR is difficult to be made such redesign. This is mainly because the motion of the manipulator will bring heavy coupling between itself and the RFR system, which makes the system model highly complicated and the controller design difficult. Thus, in this paper, the modeling, analysis, and control of the combined system, called rotor-flying multijoint manipulator (RF-MJM, are conducted. Firstly, the detailed dynamics model is constructed and analyzed. Subsequently, a full-state feedback linear quadratic regulator (LQR controller is designed through obtaining linearized model near steady state. Finally, simulations are conducted and the results are analyzed to show the basic control performance.

  19. Controllability analysis of protein glycosylation in CHO cells.

    Directory of Open Access Journals (Sweden)

    Melissa M St Amand

    Full Text Available To function as intended in vivo, a majority of biopharmaceuticals require specific glycan distributions. However, achieving a precise glycan distribution during manufacturing can be challenging because glycosylation is a non-template driven cellular process, with the potential for significant uncontrolled variability in glycan distributions. As important as the glycan distribution is to the end-use performance of biopharmaceuticals, to date, no strategy exists for controlling glycosylation on-line. However, before expending the significant amount of effort and expense required to develop and implement on-line control strategies to address the problem of glycosylation heterogeneity, it is imperative to assess first the extent to which the very complex process of glycosylation is controllable, thereby establishing what is theoretically achievable prior to any experimental attempts. In this work, we present a novel methodology for assessing the output controllability of glycosylation, a prototypical example of an extremely high-dimensional and very non-linear system. We first discuss a method for obtaining the process gain matrix for glycosylation that involves performing model simulations and data analysis systematically and judiciously according to a statistical design of experiments (DOE scheme and then employing Analysis of Variance (ANOVA to determine the elements of process gain matrix from the resulting simulation data. We then discuss how to use the resulting high-dimensional gain matrix to assess controllability. The utility of this method is demonstrated with a practical example where we assess the controllability of various classes of glycans and of specific glycoforms that are typically found in recombinant biologics produced with Chinese Hamster Ovary (CHO cells. In addition to providing useful insight into the extent to which on-line glycosylation control is achievable in actual manufacturing processes, the results also have important

  20. Multihop Medium Access Control for WSNs: An Energy Analysis Model

    Directory of Open Access Journals (Sweden)

    Haapola Jussi

    2005-01-01

    Full Text Available We present an energy analysis technique applicable to medium access control (MAC and multihop communications. Furthermore, the technique's application gives insight on using multihop forwarding instead of single-hop communications. Using the technique, we perform an energy analysis of carrier-sense-multiple-access (CSMA- based MAC protocols with sleeping schemes. Power constraints set by battery operation raise energy efficiency as the prime factor for wireless sensor networks. A detailed energy expenditure analysis of the physical, the link, and the network layers together can provide a basis for developing new energy-efficient wireless sensor networks. The presented technique provides a set of analytical tools for accomplishing this. With those tools, the energy impact of radio, MAC, and topology parameters on the network can be investigated. From the analysis, we extract key parameters of selected MAC protocols and show that some traditional mechanisms, such as binary exponential backoff, have inherent problems.

  1. A computer program for the algebraic determination of control coefficients in Metabolic Control Analysis.

    Science.gov (United States)

    Thomas, S; Fell, D A

    1993-06-01

    A computer program (MetaCon) is described for the evaluation of flux control, concentration control and branch-point distribution control coefficients of a metabolic pathway. Requiring only the reaction scheme as input, the program produces algebraic expressions for the control coefficients in terms of elasticity coefficients, metabolite concentrations and pathway fluxes. Any of these variables can be substituted by numeric or simple algebraic expressions; the expressions will then be automatically rearranged in terms of the remaining unknown variables. When all variables have been substituted, numeric values will be obtained for the control coefficients. The program is a computerized implementation of the matrix method for the determination of control coefficients. The features of MetaCon are compared with those of other programs available to workers in Metabolic Control Analysis. Potential benefits of, and methods of using, MetaCon are discussed. The mathematical background and validity of the matrix method rules are discussed, and the algorithm used by MetaCon is described. The matrix method is shown to be a specific case of a previously described general formalism for calculating control coefficients. PMID:8503870

  2. Coarse-grained Dynamic Taint Analysis for Defeating Control and Non-control Data Attacks

    CERN Document Server

    Kohli, Pankaj

    2009-01-01

    Memory corruption attacks remain the primary threat for computer security. Information flow tracking or taint analysis has been proven to be effective against most memory corruption attacks. However, there are two shortcomings with current taint analysis based techniques. First, these techniques cause application slowdown by about 76% thereby limiting their practicality. Second, these techniques cannot handle non-control data attacks i.e., attacks that do not overwrite control data such as return address, but instead overwrite critical application configuration data or user identity data. In this work, to address these problems, we describe a coarse-grained taint analysis technique that uses information flow tracking at the level of application data objects. We propagate a one-bit taint over each application object that is modified by untrusted data thereby reducing the taint management overhead considerably. We performed extensive experimental evaluation of our approach and show that it can detect all critic...

  3. Hydrothermal analysis in engineering using control volume finite element method

    CERN Document Server

    Sheikholeslami, Mohsen

    2015-01-01

    Control volume finite element methods (CVFEM) bridge the gap between finite difference and finite element methods, using the advantages of both methods for simulation of multi-physics problems in complex geometries. In Hydrothermal Analysis in Engineering Using Control Volume Finite Element Method, CVFEM is covered in detail and applied to key areas of thermal engineering. Examples, exercises, and extensive references are used to show the use of the technique to model key engineering problems such as heat transfer in nanofluids (to enhance performance and compactness of energy systems),

  4. The Role of Colour Doppler And Spectral Flow Analysis In Pregnancy Induced Hypertension: A Case Control Study

    Directory of Open Access Journals (Sweden)

    Hinal Bhagat

    2015-03-01

    Full Text Available Background: The use of Doppler ultrasound to study blood flow in Obstetrics is of major importance because fetal inaccessibility precludes many other methods of study of fetal circulation. This study was undertaken to assess the role of Doppler in management of Pregnancy induced Hypertension. Methodology: The present case-control study was conducted in the department of Radiology, Govt. Medical College and New Civil Hospital, Surat. Details of obstetric history, age, last menstrual date and underlying risk factor, Doppler study of umbilical artery, fetal middle cerebral artery, both maternal uterine arteries and Ductus venosus was done. Parameters in form of Resistive index (RI, Pulsatility index (PI and systolic/diastolic ratio (S/D of all four arteries were taken. Results: It was observed that 55% cases with pregnancy induced hypertension developed IUGR fetuses while 2% of the IUGR fetus was present in control group. There were 41 (54% cases with IUGR fetuses. Out of which 28 (68% cases with IUGR had fetoplacental Doppler abnormality. 13 cases had abnormally low PI of MCA with normal umbilical arterial Doppler indices, out of which 12 patients had abnormal fetal outcome. Conclusion: By examining the maternal vessels using Doppler ultrasound it is possible to determine, the risk of complication developing in the course of pregnancy long before clinical signs of preeclampsia appear so that therapeutic measures may be undertaken early. [Natl J Med Res 2015; 5(1.000: 57-60

  5. Sneak circuit analysis of instrumentation and control systems. [technology transfer

    Science.gov (United States)

    Rankin, J. P.; Williams, A. M.

    1974-01-01

    The evolvement and implementation is presented of a systematic means for detecting the sneak prone designs of an electrical system which could result in such unplanned modes so that they can be prevented prior to occurrence. Sneak circuit analysis is shown to be a formalized approach based upon topological techniques. The trees employed are produced from manufacturing detail data processed by a computer to orderly completion. The analysis techniques applied on a variety of NASA programs are shown to be particularly applicable to industrial instrumentation and control systems.

  6. Control of separation and quantitative analysis by GC-FTIR

    Science.gov (United States)

    Semmoud, A.; Huvenne, Jean P.; Legrand, P.

    1992-03-01

    Software for 3-D representations of the 'Absorbance-Wavenumber-Retention time' is used to control the quality of the GC separation. Spectral information given by the FTIR detection allows the user to be sure that a chromatographic peak is 'pure.' The analysis of peppermint essential oil is presented as an example. This assurance is absolutely required for quantitative applications. In these conditions, we have worked out a quantitative analysis of caffeine. Correlation coefficients between integrated absorbance measurements and concentration of caffeine are discussed at two steps of the data treatment.

  7. Analysis and test verification of control rod buffer in HTR

    International Nuclear Information System (INIS)

    The thin-walled shell buffer in high temperature gas-cooled reactor (HTR) was designed for absorbing the kinetic energy of the control rod drop in the drive line fracture accident. The thin-walled cylinder structure satisfying the requirements of actual working condition was design by using the energy absorption model of the classical cylinder shell under axial pressure. By using ABAQUS/explicit with J-C constitutive model, the finite element models of both the real reactor condition and the test condition were built to simulate the collision. Based on the analysis results, the control rod fall- down test was designed and implemented. The test results demonstrate that stable pro gressive buckling occurs when the full size buffer is impacted by equiponderance test bar, and the buffer can reduce the crush force effectively and protect the graphite from being destroyed. The analysis results show that the test model can represent and envelope the real condition in reactor. (authors)

  8. Development, analysis, and control of the inductor-converter bridge

    International Nuclear Information System (INIS)

    The inductor-converter bridge (ICB) is a solid state dc-ac-dc power converter system for bidirectional, controllable, energy transfer between two high Q magnet coils. The ICB is suitable for supplying large pulsed power to such magnets as the superconducting equilibrium field (EF) coil of the proposed tokamak power reactors, from another superconducting energy storage coil. This report presents work on the analysis and control of the ICB system. The process of energy transfer between the coils is explained on the basis of a simple one line equivalent circuit. This circuit is the topological dual of the one line diagram of the nonsalient pole synchoronous generator, connected to the infinite bus through its synchronous reactance. The changes in the average power, average coil currents, and voltages, as functions of time, are calculated by the conventional Fourier method of analysis

  9. Control and analysis software for a laser scanning microdensitometer

    Indian Academy of Sciences (India)

    H R Bundel; C P Navathe; P A Naik; P D Gupta

    2006-02-01

    A PC-based control software and data acquisition system is developed for an existing commercial microdensitometer (Biomed make model No. SL-2D/1D UV/VIS) to facilitate scanning and analysis of X-ray films. The software is developed in Labview, which includes operation of the microdensitometer in 1D and 2D scans and analysis of spatial or spectral data on X-ray films, such as optical density, intensity and wavelength. It provides a user-friendly Graphical User Interface (GUI) to analyse the scanned data and also store the analysed data/image in popular formats like data in Excel and images in jpeg. It has also on-line calibration facility with standard optical density tablets. The control software and data acquisition system is simple, inexpensive and versatile.

  10. Control System Dynamics Analysis Of TRIGA Mark II Bandung

    International Nuclear Information System (INIS)

    The root locus analysis of TRIGA MARK II reactor was performed. The parameters were calculated based from the experimental data. The experiment was performed between 100 kW to 1 MW of power, average fuel temperature was 189oC and water average temperature was 37.3oC to measure temperature and xenon poisoning feedback. On the design analysis of PID system the characteristic of the controller are gain K=2.72, tp=13.65 seconds, Mp=0.0075%, Ti=4.1 seconds and Td=0.24 seconds. The controller transient time is less than 30 seconds and the settling time is less than 2% as well

  11. Comparative Analysis of PSO Algorithms for PID Controller Tuning

    Institute of Scientific and Technical Information of China (English)

    ŠTIMAC Goranka; BRAUT Sanjin; ŽIGULIĆRoberto

    2014-01-01

    The active magnetic bearing(AMB) suspends the rotating shaft and maintains it in levitated position by applying controlled electromagnetic forces on the rotor in radial and axial directions. Although the development of various control methods is rapid, PID control strategy is still the most widely used control strategy in many applications, including AMBs. In order to tune PID controller, a particle swarm optimization(PSO) method is applied. Therefore, a comparative analysis of particle swarm optimization(PSO) algorithms is carried out, where two PSO algorithms, namely (1) PSO with linearly decreasing inertia weight(LDW-PSO), and (2) PSO algorithm with constriction factor approach(CFA-PSO), are independently tested for different PID structures. The computer simulations are carried out with the aim of minimizing the objective function defined as the integral of time multiplied by the absolute value of error(ITAE). In order to validate the performance of the analyzed PSO algorithms, one-axis and two-axis radial rotor/active magnetic bearing systems are examined. The results show that PSO algorithms are effective and easily implemented methods, providing stable convergence and good computational efficiency of different PID structures for the rotor/AMB systems. Moreover, the PSO algorithms prove to be easily used for controller tuning in case of both SISO and MIMO system, which consider the system delay and the interference among the horizontal and vertical rotor axes.

  12. Model analysis and nonlinear control of air compressors

    Science.gov (United States)

    Sari, Gholam-Reza

    For decades, gas turbines have been important, widespread, and reliable devices in the field of power generation, petrochemical industry, and aeronautics. They employ centrifugal and axial compressors which suffer from aerodynamic instabilities, namely, surge and rotating stall. These performance limiting instabilities can cause component stress, lifespan reduction, noise, and vibration. Furthermore, in variable speed axial compressors (VSACs), speed variations affect the system stability and can lead to surge and rotating stall. This limits the rate of speed variations and results in important performance penalties. The present work firstly addresses the bifurcation analysis of VSACs' model to investigate the impact of speed dynamics on the stability of efficient operating points. Here, the rate of speed variations (acceleration rate) is defined as a new parameter of the model and a detailed numerical bifurcation analysis is provided. The results of time-domain simulations not only validate the results of bifurcation analysis, but also broaden our knowledge about the transient response of the model, which is a matter of importance as well. The analysis reveals that speed variations can lead to a fully developed rotating stall as well as the previously reported temporary stall developments. The results show that the developed instabilities depend to a great extent on the acceleration rate. The impact of other key issues such as throttle gain, viscosity factor, initial speed, final speed, and the contribution of stall modes are also explored. From the control point of view, despite reported achievements, robust control design for compression systems remains a challenging problem. In this work, at first, two nonlinear approaches are proposed to tackle the stability problem of constant-speed axial compressors (CSACs). The first approach is a robust passivity-based control and the second one is a second order sliding mode control. The approaches tackle the challenging

  13. Interference control in low-level analysis of iodine 129

    International Nuclear Information System (INIS)

    This work analyses the integration of several steps applied to control potentials sources of error in the determination of 129I and prevent spurious results in order to achieve the minimum detection limit. The procedure of pre and post-irradiation purification, neutron irradiation, radioactive counting and data analysis are needed. High resolution gamma spectrometry was used for detection and measurement of low level interferences. (author)

  14. A Complete Analysis for Pump Controlled Single Rod Actuators

    OpenAIRE

    Çalışkan,Hakan; Balkan, Tuna; Platin, Bülent E.

    2016-01-01

    In the current study a variable speed pump controlled hydrostatic circuit where an underlapped shuttle valve is utilized to compensate the unequal flow rate of a single rod actuator is analyzed. Parameters of the shuttle valve are included in the system analysis, rather than treating it as an ideal switching element as handled in literature. A linearized model of the system is obtained. An inverse kinematic model, which calculates the required pump drive speed for a desired actuator speed and...

  15. Recurrent reciprocal deletions and duplications of 16p13.11: the deletion is a risk factor for MR/MCA while the duplication may be a rare benign variant

    OpenAIRE

    Hannes, F.D.; Sharp, A. J.; Mefford, H.C.; Ravel, de, T.; Ruivenkamp, C A; Breuning, M.H.; Fryns, J P; Devriendt, K; Buggenhout, van, G.; Vogels, A.; Stewart, H. H.; Hennekam, R. C.; Cooper, G M; Regan, R.; Knight, S.J.

    2009-01-01

    Background: Genomic disorders are often caused by non-allelic homologous recombination between segmental duplications. Chromosome 16 is especially rich in a chromosome-specific low copy repeat, termed LCR16. Methods and Results: A bacterial artificial chromosome (BAC) array comparative genome hybridisation (CGH) screen of 1027 patients with mental retardation and/or multiple congenital anomalies (MR/MCA) was performed. The BAC array CGH screen identified five patients with deletions and five ...

  16. Deviation from optimal vascular caliber control at middle cerebral artery bifurcations harboring aneurysms.

    Science.gov (United States)

    Baharoglu, Merih I; Lauric, Alexandra; Wu, Chengyuan; Hippelheuser, James; Malek, Adel M

    2014-10-17

    Cerebral aneurysms form preferentially at arterial bifurcations. The vascular optimality principle (VOP) decrees that minimal energy loss across bifurcations requires optimal caliber control between radii of parent (r₀) and daughter branches (r1 and r2): r₀(n)=r₁(n)+r₂(n), with n approximating three. VOP entails constant wall shear stress (WSS), an endothelial phenotype regulator. We sought to determine if caliber control is maintained in aneurysmal intracranial bifurcations. Three-dimensional rotational angiographic volumes of 159 middle cerebral artery (MCA) bifurcations (62 aneurysmal) were processed using 3D gradient edge-detection filtering, enabling threshold-insensitive radius measurement. Radius ratio (RR)=r₀(3)/(r₁(3)+r₂(3)) and estimated junction exponent (n) were compared between aneurysmal and non-aneurysmal bifurcations using Student t-test and Wilcoxon rank-sum analysis. The results show that non-aneurysmal bifurcations display optimal caliber control with mean RR of 1.05 and median n of 2.84. In contrast, aneurysmal bifurcations had significantly lower RR (0.76, pbifurcations revealed a daughter branch larger than its parent vessel, an absolute violation of optimality, not witnessed in non-aneurysmal bifurcations. The aneurysms originated more often off the smaller daughter (52%) vs. larger daughter branch (16%). Aneurysm size was not statistically correlated to RR or n. Aneurysmal males showed higher deviation from VOP. Non-aneurysmal MCA bifurcations contralateral to aneurysmal ones showed optimal caliber control. Aneurysmal bifurcations, in contrast to non-aneurysmal counterparts, disobey the VOP and may exhibit dysregulation in WSS-mediated caliber control. The mechanism of this focal divergence from optimality may underlie aneurysm pathogenesis and requires further study.

  17. Intelligent Control in Automation Based on Wireless Traffic Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kurt Derr; Milos Manic

    2007-08-01

    Wireless technology is a central component of many factory automation infrastructures in both the commercial and government sectors, providing connectivity among various components in industrial realms (distributed sensors, machines, mobile process controllers). However wireless technologies provide more threats to computer security than wired environments. The advantageous features of Bluetooth technology resulted in Bluetooth units shipments climbing to five million per week at the end of 2005 [1, 2]. This is why the real-time interpretation and understanding of Bluetooth traffic behavior is critical in both maintaining the integrity of computer systems and increasing the efficient use of this technology in control type applications. Although neuro-fuzzy approaches have been applied to wireless 802.11 behavior analysis in the past, a significantly different Bluetooth protocol framework has not been extensively explored using this technology. This paper presents a new neurofuzzy traffic analysis algorithm of this still new territory of Bluetooth traffic. Further enhancements of this algorithm are presented along with the comparison against the traditional, numerical approach. Through test examples, interesting Bluetooth traffic behavior characteristics were captured, and the comparative elegance of this computationally inexpensive approach was demonstrated. This analysis can be used to provide directions for future development and use of this prevailing technology in various control type applications, as well as making the use of it more secure.

  18. Intelligent Control in Automation Based on Wireless Traffic Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kurt Derr; Milos Manic

    2007-09-01

    Wireless technology is a central component of many factory automation infrastructures in both the commercial and government sectors, providing connectivity among various components in industrial realms (distributed sensors, machines, mobile process controllers). However wireless technologies provide more threats to computer security than wired environments. The advantageous features of Bluetooth technology resulted in Bluetooth units shipments climbing to five million per week at the end of 2005 [1, 2]. This is why the real-time interpretation and understanding of Bluetooth traffic behavior is critical in both maintaining the integrity of computer systems and increasing the efficient use of this technology in control type applications. Although neuro-fuzzy approaches have been applied to wireless 802.11 behavior analysis in the past, a significantly different Bluetooth protocol framework has not been extensively explored using this technology. This paper presents a new neurofuzzy traffic analysis algorithm of this still new territory of Bluetooth traffic. Further enhancements of this algorithm are presented along with the comparison against the traditional, numerical approach. Through test examples, interesting Bluetooth traffic behavior characteristics were captured, and the comparative elegance of this computationally inexpensive approach was demonstrated. This analysis can be used to provide directions for future development and use of this prevailing technology in various control type applications, as well as making the use of it more secure.

  19. Detrended Fluctuation Analysis of Systolic Blood Pressure Control Loop

    CERN Document Server

    Galhardo, C E C; de Menezes, M Argollo; Soares, P P S

    2009-01-01

    We use detrended fluctuation analysis (DFA) to study the dynamics of blood pressure oscillations and its feedback control in rats by analyzing systolic pressure time series before and after a surgical procedure that interrupts its control loop. We found, for each situation, a crossover between two scaling regions characterized by exponents that reflect the nature of the feedback control and its range of operation. In addition, we found evidences of adaptation in the dynamics of blood pressure regulation a few days after surgical disruption of its main feedback circuit. Based on the paradigm of antagonistic, bipartite (vagal and sympathetic) action of the central nerve system, we propose a simple model for pressure homeostasis as the balance between two nonlinear opposing forces, successfully reproducing the crossover observed in the DFA of actual pressure signals.

  20. Metabolic control analysis of Aspergillus niger L-arabinose catabolism

    DEFF Research Database (Denmark)

    de Groot, M.J.L.; Prathumpai, Wai; Visser, J.;

    2005-01-01

    , and their kinetic properties were characterized. For the other enzymes of the pathway the kinetic data were available from the literature. The metabolic model was used to analyze flux and metabolite concentration control of the L-arabinose catabolic pathway. The model demonstrated that flux control does not reside......A mathematical model of the L-arabinose/D-xylose catabolic pathway of Aspergillus niger was constructed based on the kinetic properties of the enzymes. For this purpose L-arabinose reductase, L-arabitol dehydrogenase and D-xylose reductase were purified using dye-affinity chromatography......-arabinose, a level that resulted in realistic intermediate concentrations in the model, flux control coefficients for L-arabinose reductase, L-arabitol dehydrogenase and L-xylulose reductase were 0.68, 0.17 and 0.14, respectively. The analysis can be used as a guide to identify targets for metabolic engineering...

  1. Characterizing the human postural control system using detrended fluctuation analysis

    Science.gov (United States)

    Teresa Blázquez, M.; Anguiano, Marta; de Saavedra, Fernando Arias; Lallena, Antonio M.; Carpena, Pedro

    2010-01-01

    Detrended fluctuation analysis is used to study the behaviour of the time series of the position of the center of pressure, output from the activity of a human postural control system. The results suggest that these trajectories present a crossover in their scaling properties from persistent (for high frequencies, short-range time scale) to anti-persistent (for low frequencies, long-range time scale) behaviours. The values of the scaling exponent found for the persistent parts of the trajectories are very similar for all the cases analysed. The similarity of the results obtained for the measurements done with both eyes open and both eyes closed indicate either that the visual system may be disregarded by the postural control system, while maintaining quiet standing, or that the control mechanisms associated with each type of information (visual, vestibular and somatosensory) cannot be disentangled with this technique.

  2. Quality Assurance and Control in Laboratory using Neutron Activation Analysis

    International Nuclear Information System (INIS)

    In accordance with the increment of international trade associated with the worldwide globalization, the importance of quality assurance and control for the commodity produced from one's own country has been stressed. ISO (International Organization for Standards) defines quality control as 'the operational techniques and activities that are used to fulfill the requirements for quality'. Since 1996, the HANARO research reactor in the Korea Atomic Energy Research Institute has been operated thereafter initial critical operation on April 1995. Neutron activation analysis system and applied techniques which is one of a nuclear analytical technologies using reactor neutrons has been developed for user's supporting and the establishment of the quality system for a measurement and analysis, testing and inspection was implemented successfully. On the basis of the qualified NAA system, the test and measurement of more than 1500 samples which is requested from 30 organizations including industrial companies, universities and institutes carried out in NAA laboratory annually. Moreover, as the goal of mutual recognition agreement (MRA) which can be removed a technical barrier in international trade, the objectivity and the confidence of analytical quality in NAA laboratory became established through the installation of international accreditation system by implementing analytical quality system in accordance with international standards in 2001. The aim of the report was to summarize the technical management of introduction, methods and the results for a quality control and assurance which should be performed in NAA technique using the HANARO research reactor. The report will help building up effective quality control strategy in the future

  3. CUSUM control charts based on likelihood ratio for preliminary analysis

    Institute of Scientific and Technical Information of China (English)

    Yi DAI; Zhao-jun WANG; Chang-liang ZOU

    2007-01-01

    To detect and estimate a shift in either the mean and the deviation or both for the preliminary analysis, the statistical process control (SPC) tool, the control chart based on the likelihood ratio test (LRT), is the most popular method.Sullivan and woodall pointed out the test statistic lrt (n1, n2) is approximately distributed as x2 (2) as the sample size n, n1 and n2 are very large, and the value of n1 = 2, 3,..., n- 2 and that of n2 = n- n1.So it is inevitable that n1 or n2 is not large. In this paper the limit distribution of lrt(n1, n2) for fixed n1 or n2 is figured out, and the exactly analytic formulae for evaluating the expectation and the variance of the limit distribution are also obtained.In addition, the properties of the standardized likelihood ratio statistic slr(n1,n) are discussed in this paper. Although slr(n1, n) contains the most important information, slr(i, n)(i ≠ n1) also contains lots of information. The cumulative sum (CUSUM) control chart can obtain more information in this condition. So we propose two CUSUM control charts based on the likelihood ratio statistics for the preliminary analysis on the individual observations. One focuses on detecting the shifts in location in the historical data and the other is more general in detecting a shift in either the location and the scale or both.Moreover, the simulated results show that the proposed two control charts are, respectively, superior to their competitors not only in the detection of the sustained shifts but also in the detection of some other out-of-control situations considered in this paper.

  4. CUSUM control charts based on likelihood ratio for preliminary analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    To detect and estimate a shift in either the mean and the deviation or both for the preliminary analysis, the statistical process control (SPC) tool, the control chart based on the likelihood ratio test (LRT), is the most popular method. Sullivan and woodall pointed out the test statistic lrt(n1, n2) is approximately distributed as x2(2) as the sample size n,n1 and n2 are very large, and the value of n1 = 2,3,..., n - 2 and that of n2 = n - n1. So it is inevitable that n1 or n2 is not large. In this paper the limit distribution of lrt(n1, n2) for fixed n1 or n2 is figured out, and the exactly analytic formulae for evaluating the expectation and the variance of the limit distribution are also obtained. In addition, the properties of the standardized likelihood ratio statistic slr(n1, n) are discussed in this paper. Although slr(n1, n) contains the most important information, slr(i, n)(i≠n1) also contains lots of information. The cumulative sum (CUSUM) control chart can obtain more information in this condition. So we propose two CUSUM control charts based on the likelihood ratio statistics for the preliminary analysis on the individual observations. One focuses on detecting the shifts in location in the historical data and the other is more general in detecting a shift in either the location and the scale or both. Moreover, the simulated results show that the proposed two control charts are, respectively, superior to their competitors not only in the detection of the sustained shifts but also in the detection of some other out-of-control situations considered in this paper.

  5. Transient analysis of energy Transfer Control (ECT) and compressor bleed concepts of remote lift fan control

    Science.gov (United States)

    Sellers, J. F.

    1973-01-01

    The transient performance of two concepts for control of vertical takeoff aircraft remote lift fans is analyzed and discussed. Both concepts employ flow transfer between pairs of lift fans located in separate parts of the aircraft in order to obtain attitude control moments for hover and low-speed flight. The results presented are from a digital computer, dynamic analysis of the YJ97/LF460 remote drive turbofan. The transient responses of the two systems are presented for step demands in lift and moment.

  6. 78 FR 71532 - Amendments to Material Control and Accounting Regulations and Proposed Guidance for Fuel Cycle...

    Science.gov (United States)

    2013-11-29

    ...: I. Background On November 8, 2013 (78 FR 67225; NRC-2009-0096), the NRC published for public comment a proposed rule to amend its regulations for MC&A of SNM. Also on November 8, 2013 (78 FR 67224; NRC... Control and Accounting Regulations and Proposed Guidance for Fuel Cycle Facility Material Control...

  7. Evaluation of dairy effluent management options using multiple criteria analysis.

    Science.gov (United States)

    Hajkowicz, Stefan A; Wheeler, Sarah A

    2008-04-01

    This article describes how options for managing dairy effluent on the Lower Murray River in South Australia were evaluated using multiple criteria analysis (MCA). Multiple criteria analysis is a framework for combining multiple environmental, social, and economic objectives in policy decisions. At the time of the study, dairy irrigation in the region was based on flood irrigation which involved returning effluent to the river. The returned water contained nutrients, salts, and microbial contaminants leading to environmental, human health, and tourism impacts. In this study MCA was used to evaluate 11 options against 6 criteria for managing dairy effluent problems. Of the 11 options, the MCA model selected partial rehabilitation of dairy paddocks with the conversion of remaining land to other agriculture. Soon after, the South Australian Government adopted this course of action and is now providing incentives for dairy farmers in the region to upgrade irrigation infrastructure and/or enter alternative industries.

  8. Subtracted dynamic MR perfusion source images (sMRP-SI) provide collateral blood flow assessment in MCA occlusions and predict tissue fate

    Energy Technology Data Exchange (ETDEWEB)

    Villringer, Kersten; Serrano-Sandoval, Rafael; Galinovic, Ivana; Ostwaldt, Ann-Christin; Brunecker, Peter; Fiebach, Jochen B. [Charite-Universitaetsmedizin, Academic Neuroradiology, Center for Stroke Research (CSB), Berlin (Germany); Grittner, Ulrike [Charite, Universitaetsmedizin Berlin, Center for Stroke Research, Berlin (Germany); Charite, Department for Biostatistics and Clinical Epidemiology, Berlin (Germany); Schneider, Alice [Charite, Universitaetsmedizin Berlin, Center for Stroke Research, Berlin (Germany); Rocco, Andrea [Charite, Department of Neurology and Center for Stroke Research, Berlin (Germany)

    2016-05-15

    Collateral blood flow is accepted as a predictive factor of tissue fate in ischemic stroke. Thus, we aimed to evaluate a new method derived from MR perfusion source images to assess collateral flow in patients with ICA/MCA occlusions. A total of 132 patients of the prospective 1000+ study were examined. MR perfusion source images were assessed according to Δimg{sub n} = img{sub n} + 1 - img{sub n} - 1 using the five-grade Higashida collateral flow rating system. Higashida scores were correlated to mismatch (MM) volume, mismatch ratio, day 6 FLAIR lesion volumes and day 90 mRS. Patients with Higashida scores 3 and 4 had significantly lower admission NIHSS, smaller FLAIR day 6 lesion volumes (p < 0.001) and higher rates of better long-term outcome (mRS 0-2, p = 0.002). There was a linear trend for the association of Higashida grade 1 (p = 0.002) and 2 (p = 0.001) with unfavourable outcome (day 90 mRS 3-6), but no significant association was found for MM volume, MM ratio and day 90 mRS. Inter-rater agreement was 0.58 (95 % CI 0.43-0.73) on day 1, 0.70 (95 % CI 0.58-0.81) on day 2. sMRP-SI Higashida score offers a non-invasive collateral vessel and tissue perfusion assessment of ischemic tissue. The predictive value of Higashida rating proved superior to MM with regard to day 90 mRS. (orig.)

  9. Production and in vitro characterization of 3D porous scaffolds made of magnesium carbonate apatite (MCA)/anionic collagen using a biomimetic approach

    Energy Technology Data Exchange (ETDEWEB)

    Sader, Marcia S., E-mail: msader@metalmat.ufrj.br [Prog. Engenharia Metalúrgica e Materiais, COPPE/UFRJ, RJ (Brazil); Martins, Virginia C.A. [Depto. de Química e Física Molecular, IQSC/USP, SP (Brazil); Gomez, Santiago [Dept. Anatomía Patológica, Universidad de Cádiz, Cadiz (Spain); LeGeros, Racquel Z. [Department of Biomaterials and Biomimetics, New York University College of Dentistry, NY (United States); Soares, Gloria A. [Prog. Engenharia Metalúrgica e Materiais, COPPE/UFRJ, RJ (Brazil)

    2013-10-15

    3D porous scaffolds are relevant biomaterials to bone engineering as they can be used as templates to tissue reconstruction. The aim of the present study was to produce and characterize in vitro 3D magnesium-carbonate apatite/collagen (MCA/col) scaffolds. They were prepared by using biomimetic approach, followed by cross-linking with 0.25% glutaraldehyde solution (GA) and liofilization. Results obtained with Fourier-transform infrared spectroscopy (FT-IR) confirmed the type-B carbonate substitution, while by X-ray diffraction (XRD), a crystallite size of ∼ 10 nm was obtained. Optical and electron microscopy showed that the cylindrical samples exhibited an open-porous morphology, with apatite nanocrystals precipitated on collagen fibrils. The cross-linked 3D scaffolds showed integrity when immersed in culture medium up to 14 days. Also, the immersion of such samples into an acid buffer solution, to mimic the osteoclastic resorption environment, promotes the release of important ions for bone repair, such as calcium, phosphorus and magnesium. Bone cells (SaOs2) adhered, and proliferated on the 3D composite scaffolds, showing that synthesis and the cross-linking processes did not induce cytotoxicity. Highlights: • 3D scaffolds of Mg-carbonate–apatite and anionic-collagen were produced. • The biomimetic approach and the cross-linking with 0.25% GA solution were employed. • The scaffolds showed open-porous structure and apatite crystals on collagen fibrils. • The cross-linked scaffolds exhibited integrity when immersed in culture medium. • SaOs2 cells adhered and proliferated on the cross-linked scaffolds confirming no cytotoxicity.

  10. Subtracted dynamic MR perfusion source images (sMRP-SI) provide collateral blood flow assessment in MCA occlusions and predict tissue fate

    International Nuclear Information System (INIS)

    Collateral blood flow is accepted as a predictive factor of tissue fate in ischemic stroke. Thus, we aimed to evaluate a new method derived from MR perfusion source images to assess collateral flow in patients with ICA/MCA occlusions. A total of 132 patients of the prospective 1000+ study were examined. MR perfusion source images were assessed according to Δimgn = imgn + 1 - imgn - 1 using the five-grade Higashida collateral flow rating system. Higashida scores were correlated to mismatch (MM) volume, mismatch ratio, day 6 FLAIR lesion volumes and day 90 mRS. Patients with Higashida scores 3 and 4 had significantly lower admission NIHSS, smaller FLAIR day 6 lesion volumes (p < 0.001) and higher rates of better long-term outcome (mRS 0-2, p = 0.002). There was a linear trend for the association of Higashida grade 1 (p = 0.002) and 2 (p = 0.001) with unfavourable outcome (day 90 mRS 3-6), but no significant association was found for MM volume, MM ratio and day 90 mRS. Inter-rater agreement was 0.58 (95 % CI 0.43-0.73) on day 1, 0.70 (95 % CI 0.58-0.81) on day 2. sMRP-SI Higashida score offers a non-invasive collateral vessel and tissue perfusion assessment of ischemic tissue. The predictive value of Higashida rating proved superior to MM with regard to day 90 mRS. (orig.)

  11. Economic analysis of HPAI control in the Netherlands II: comparison of control strategies.

    Science.gov (United States)

    Longworth, N; Mourits, M C M; Saatkamp, H W

    2014-06-01

    A combined epidemiological-economic modelling approach was used to analyse strategies for highly pathogenic avian influenza (HPAI) control for the Netherlands. The modelling framework used was InterSpread Plus (ISP), a spatially based, stochastic and dynamic simulation model. A total of eight control strategies were analysed, including pre-emptive depopulation and vaccination strategies. The analysis was carried out for three different regions in the Netherlands: high-, medium- and low-density areas (HDA, MDA and LDA, respectively). The analysis included the veterinary impact (e.g. number of infected premises and duration), but was particularly focused on the impact on direct costs (DC) and direct consequential costs. The efficient set of control strategies for HDA and MDA included strategies based on either pre-emptive depopulation only or combined vaccination and pre-emptive depopulation: D2 (pre-emptive depopulation within a radius of 2 km), RV3 + D1 (ring vaccination within a radius of 3 km and additional pre-emptive depopulation within a radius of 1 km) and PV + D1 (preventive vaccination in non-affected HDAs and pre-emptive depopulation within a radius of 1 km in the affected HDA). Although control solely based on depopulation in most cases showed to be effective for LDA, pre-emptive depopulation showed to have an additional advantage in these areas, that is, prevention of 'virus jumps' to other areas. The pros and cons of the efficient control strategies were discussed, for example, public perception and risk of export restrictions. It was concluded that for the Netherlands control of HPAI preferably should be carried out using strategies including pre-emptive depopulation with or without vaccination. Particularly, the short- and long-term implications on export, that is, indirect consequential costs (ICC) and aftermath costs of these strategies, should be analysed further.

  12. Nanosilicon properties, synthesis, applications, methods of analysis and control

    CERN Document Server

    Ischenko, Anatoly A; Aslalnov, Leonid A

    2015-01-01

    Nanosilicon: Properties, Synthesis, Applications, Methods of Analysis and Control examines the latest developments on the physics and chemistry of nanosilicon. The book focuses on methods for producing nanosilicon, its electronic and optical properties, research methods to characterize its spectral and structural properties, and its possible applications. The first part of the book covers the basic properties of semiconductors, including causes of the size dependence of the properties, structural and electronic properties, and physical characteristics of the various forms of silicon. It presents theoretical and experimental research results as well as examples of porous silicon and quantum dots. The second part discusses the synthesis of nanosilicon, modification of the surface of nanoparticles, and properties of the resulting particles. The authors give special attention to the photoluminescence of silicon nanoparticles. The third part describes methods used for studying and controlling the structure and pro...

  13. New Applications of Variational Analysis to Optimization and Control

    Science.gov (United States)

    Mordukhovich, Boris S.

    We discuss new applications of advanced tools of variational analysis and generalized differentiation to a number of important problems in optimization theory, equilibria, optimal control, and feedback control design. The presented results are largely based on the recent work by the author and his collaborators. Among the main topics considered and briefly surveyed in this paper are new calculus rules for generalized differentiation of nonsmooth and set-valued mappings; necessary and sufficient conditions for new notions of linear subextremality and suboptimality in constrained problems; optimality conditions for mathematical problems with equilibrium constraints; necessary optimality conditions for optimistic bilevel programming with smooth and nonsmooth data; existence theorems and optimality conditions for various notions of Pareto-type optimality in problems of multiobjective optimization with vector-valued and set-valued cost mappings; Lipschitzian stability and metric regularity aspects for constrained and variational systems.

  14. Muscle networks: Connectivity analysis of EMG activity during postural control

    Science.gov (United States)

    Boonstra, Tjeerd W.; Danna-Dos-Santos, Alessander; Xie, Hong-Bo; Roerdink, Melvyn; Stins, John F.; Breakspear, Michael

    2015-12-01

    Understanding the mechanisms that reduce the many degrees of freedom in the musculoskeletal system remains an outstanding challenge. Muscle synergies reduce the dimensionality and hence simplify the control problem. How this is achieved is not yet known. Here we use network theory to assess the coordination between multiple muscles and to elucidate the neural implementation of muscle synergies. We performed connectivity analysis of surface EMG from ten leg muscles to extract the muscle networks while human participants were standing upright in four different conditions. We observed widespread connectivity between muscles at multiple distinct frequency bands. The network topology differed significantly between frequencies and between conditions. These findings demonstrate how muscle networks can be used to investigate the neural circuitry of motor coordination. The presence of disparate muscle networks across frequencies suggests that the neuromuscular system is organized into a multiplex network allowing for parallel and hierarchical control structures.

  15. Cost-benefit analysis of avian influenza control in Nepal.

    Science.gov (United States)

    Karki, S; Lupiani, B; Budke, C M; Karki, N P S; Rushton, J; Ivanek, R

    2015-12-01

    Numerous outbreaks of highly pathogenic avian influenza A strain H5N1 have occurred in Nepal since 2009 despite implementation of a national programme to control the disease through surveillance and culling of infected poultry flocks. The objective of the study was to use cost-benefit analysis to compare the current control programme (CCP) with the possible alternatives of: i) no intervention (i.e., absence of control measures [ACM]) and ii) vaccinating 60% of the national poultry flock twice a year. In terms of the benefit-cost ratio, findings indicate a return of US $1.94 for every dollar spent in the CCP compared with ACM. The net present value of the CCP versus ACM, i.e., the amount of money saved by implementing the CCP rather than ACM, is US $861,507 (the benefits of CCP [prevented losses which would have occurred under ACM] minus the cost of CCP). The vaccination programme yields a return of US $2.32 for every dollar spent when compared with the CCR The net present value of vaccination versus the CCP is approximately US $12 million. Sensitivity analysis indicated thatthe findings were robust to different rates of discounting, whereas results were sensitive to the assumed market loss and the number of birds affected in the outbreaks under the ACM and vaccination options. Overall, the findings of the study indicate that the CCP is economically superior to ACM, but that vaccination could give greater economic returns and may be a better control strategy. Future research should be directed towards evaluating the financial feasibility and social acceptability of the CCP and of vaccination, with an emphasis on evaluating market reaction to the presence of H5N1 infection in the country.

  16. Quality Assurance and Control in Laboratory using Neutron Activation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Sun, G. M.; Kim, S. H.; Baek, S. Y.; Lim, J. M.; Kim, H. R

    2007-01-15

    In accordance with the increment of international trade associated with the worldwide globalization, the importance of quality assurance and control for the commodity produced from one's own country has been stressed. ISO (International Organization for Standards) defines quality control as 'the operational techniques and activities that are used to fulfill the requirements for quality'. Since 1996, the HANARO research reactor in the Korea Atomic Energy Research Institute has been operated thereafter initial critical operation on April 1995. Neutron activation analysis system and applied techniques which is one of a nuclear analytical technologies using reactor neutrons has been developed for user's supporting and the establishment of the quality system for a measurement and analysis, testing and inspection was implemented successfully. On the basis of the qualified NAA system, the test and measurement of more than 1500 samples which is requested from 30 organizations including industrial companies, universities and institutes carried out in NAA laboratory annually. Moreover, as the goal of mutual recognition agreement (MRA) which can be removed a technical barrier in international trade, the objectivity and the confidence of analytical quality in NAA laboratory became established through the installation of international accreditation system by implementing analytical quality system in accordance with international standards in 2001. The aim of the report was to summarize the technical management of introduction, methods and the results for a quality control and assurance which should be performed in NAA technique using the HANARO research reactor. The report will help building up effective quality control strategy in the future.

  17. Analysis and optimization of delays in networked control systems

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The minimization problem of time delays in networked control system (NCS) is concered, which is a hot area of such research field. First, some analysis and comments on time-delayed NCS model listed in previous work are given.Then, time delay minimization problem based on average behavior of network queuing delay is presented. Under fixed routing scheme and certain optimization performance indexes, the delay minimization problem is translated into convex optimization problem. And the solution of the delay minimization problems is attained through optimized allocation of flow rates among network links.

  18. Design and Performance Analysis of ZBT SRAM Controller

    Directory of Open Access Journals (Sweden)

    Smriti Sharma

    2013-07-01

    Full Text Available Memory is an essential part of electronic industry. Since, the processors used in various high performancePCs, network applications and communication equipment require high speed memories. The type ofmemory used depends on system architecture, and its applications. This paper presents an SRAMarchitecture known as Zero Bus Turnaround (ZBT. This ZBT SRAM is mainly developed for networkingapplications where frequent READ/WRITE transitions are required. The other single data rate SRAMs areinefficient as they require idle cycles when they frequently switch between reading and writing to thememory. This controller is simulated on the Spartan 3 device. And the performance analysis is done on thebasis of area, speed and power.

  19. Control of pneumatic transfer system for neutron activation analysis

    International Nuclear Information System (INIS)

    Pneumatic transfer system(PTS) is one of the facilities to be used in irradiation of target materials for neutron activation analysis(NAA) in the research reactor. There are two systems the manual and the automatic system in PTS of HANARO research reactor. The pneumatic transfer system consists of many devices, sends and loads the capsules from NAA laboratory into three holes in the reflector tank of reactor and retrieves irradiated capsules after irradiation. This report describes the part's design, control system and the operation procedures. All the algorithm described in the text will be used for maintenance and upgrading

  20. Robustness analysis of control systems with disc uncertainties

    Institute of Scientific and Technical Information of China (English)

    Zhizhen WANG; Long WANG; Wensheng YU

    2005-01-01

    For a class of control systems with disc uncertainties, robust performance analysis is developed. On the strictly positive realness and H-infinity-norm of uncertain systems, from the geometric point of view, two new sufficient and necessary conditions are given. The largest H-infinity-norm bound, containing the coefficients of only stable polynomials and centered at a nominal stable point in the coecient space is found. The results obtained in the paper are tractable and concise, which is illustrated by some numerical examples.

  1. Control of pneumatic transfer system for neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jung, H. S.; Chung, Y. S.; Wu, J. S.; Kim, H. K.; Choi, Y. S.; Kim, S. H.; Moon, J. H.; Baek, S. Y

    2000-06-01

    Pneumatic transfer system(PTS) is one of the facilities to be used in irradiation of target materials for neutron activation analysis(NAA) in the research reactor. There are two systems the manual and the automatic system in PTS of HANARO research reactor. The pneumatic transfer system consists of many devices, sends and loads the capsules from NAA laboratory into three holes in the reflector tank of reactor and retrieves irradiated capsules after irradiation. This report describes the part's design, control system and the operation procedures. All the algorithm described in the text will be used for maintenance and upgrading.

  2. Cost Effectiveness Analysis of Optimal Malaria Control Strategies in Kenya

    Directory of Open Access Journals (Sweden)

    Gabriel Otieno

    2016-03-01

    Full Text Available Malaria remains a leading cause of mortality and morbidity among the children under five and pregnant women in sub-Saharan Africa, but it is preventable and controllable provided current recommended interventions are properly implemented. Better utilization of malaria intervention strategies will ensure the gain for the value for money and producing health improvements in the most cost effective way. The purpose of the value for money drive is to develop a better understanding (and better articulation of costs and results so that more informed, evidence-based choices could be made. Cost effectiveness analysis is carried out to inform decision makers on how to determine where to allocate resources for malaria interventions. This study carries out cost effective analysis of one or all possible combinations of the optimal malaria control strategies (Insecticide Treated Bednets—ITNs, Treatment, Indoor Residual Spray—IRS and Intermittent Preventive Treatment for Pregnant Women—IPTp for the four different transmission settings in order to assess the extent to which the intervention strategies are beneficial and cost effective. For the four different transmission settings in Kenya the optimal solution for the 15 strategies and their associated effectiveness are computed. Cost-effective analysis using Incremental Cost Effectiveness Ratio (ICER was done after ranking the strategies in order of the increasing effectiveness (total infections averted. The findings shows that for the endemic regions the combination of ITNs, IRS, and IPTp was the most cost-effective of all the combined strategies developed in this study for malaria disease control and prevention; for the epidemic prone areas is the combination of the treatment and IRS; for seasonal areas is the use of ITNs plus treatment; and for the low risk areas is the use of treatment only. Malaria transmission in Kenya can be minimized through tailor-made intervention strategies for malaria control

  3. Cost-benefit analysis in animal disease control

    International Nuclear Information System (INIS)

    Animal health economics is a relatively new discipline which is progressively developing a solid framework of concepts, procedures and data to support the decision making process in optimizing animal health management. Research in this field deals primarily with three interrelated aspects: (1) quantifying the financial effects of animal diseases, (2) developing methods for optimizing decisions when individual animals, herds or populations are affected, and (3) determining the costs and benefits of disease control measures. In the paper the four most common economic modelling techniques in animal health economics (i.e. partial budgeting, cost-benefit analysis, decision analysis, and systems simulation) are described and applied on three levels of veterinary decision making: the animal, herd and national level. Outcomes so far are summarized, and shortcomings indicated and discussed. The importance of a close link between economics and epidemiology is stressed for future development, as well as the need for, and possibilities of, an international exchange of models and procedures. (author)

  4. Towards a controlled sensitivity analysis of model development decisions

    Science.gov (United States)

    Clark, Martyn; Nijssen, Bart

    2016-04-01

    The current generation of hydrologic models have followed a myriad of different development paths, making it difficult for the community to test underlying hypotheses and identify a clear path to model improvement. Model comparison studies have been undertaken to explore model differences, but these studies have not been able to meaningfully attribute inter-model differences in predictive ability to individual model components because there are often too many structural and implementation differences among the models considered. As a consequence, model comparison studies to date have provided limited insight into the causes of differences in model behavior, and model development has often relied on the inspiration and experience of individual modelers rather than a systematic analysis of model shortcomings. This presentation will discuss a unified approach to process-based hydrologic modeling to enable controlled and systematic analysis of multiple model representations (hypotheses) of hydrologic processes and scaling behavior. Our approach, which we term the Structure for Unifying Multiple Modeling Alternatives (SUMMA), formulates a general set of conservation equations, providing the flexibility to experiment with different spatial representations, different flux parameterizations, different model parameter values, and different time stepping schemes. We will discuss the use of SUMMA to systematically analyze different model development decisions, focusing on both analysis of simulations for intensively instrumented research watersheds as well as simulations across a global dataset of FLUXNET sites. The intent of the presentation is to demonstrate how the systematic analysis of model shortcomings can help identify model weaknesses and inform future model development priorities.

  5. An Analysis of the Control Hierarchy Modelling of the CMS Detector Control System

    Science.gov (United States)

    Hwong, Yi Ling; Willemse, Tim; Kusters, Vincent; Bauer, Gerry; Beccati, Barbara; Behrens, Ulf; Biery, Kurt; Bouffet, Olivier; Branson, James; Bukowiec, Sebastian; Cano, Eric; Cheung, Harry; Ciganek, Marek; Cittolin, Sergio; Coarasa, Jose Antonio; Deldicque, Christian; Dupont, Aymeric; Erhan, Samim; Gigi, Dominique; Glege, Frank; Gomez-Reino, Robert; Holzner, Andre; Hatton, Derek; Masetti, Lorenzo; Meijers, Frans; Meschi, Emilio; Mommsen, Remigius K.; Moser, Roland; O'Dell, Vivian; Orsini, Luciano; Paus, Christoph; Petrucci, Andrea; Pieri, Marco; Racz, Attila; Raginel, Olivier; Sakulin, Hannes; Sani, Matteo; Schieferdeckerb, Philipp; Schwick, Christoph; Shpakov, Dennis; Simon, Michal; Sumorok, Konstanty

    2011-12-01

    The supervisory level of the Detector Control System (DCS) of the CMS experiment is implemented using Finite State Machines (FSM), which model the behaviours and control the operations of all the sub-detectors and support services. The FSM tree of the whole CMS experiment consists of more than 30.000 nodes. An analysis of a system of such size is a complex task but is a crucial step towards the improvement of the overall performance of the FSM system. This paper presents the analysis of the CMS FSM system using the micro Common Representation Language 2 (mcrl2) methodology. Individual mCRL2 models are obtained for the FSM systems of the CMS sub-detectors using the ASF+SDF automated translation tool. Different mCRL2 operations are applied to the mCRL2 models. A mCRL2 simulation tool is used to closer examine the system. Visualization of a system based on the exploration of its state space is enabled with a mCRL2 tool. Requirements such as command and state propagation are expressed using modal mu-calculus and checked using a model checking algorithm. For checking local requirements such as endless loop freedom, the Bounded Model Checking technique is applied. This paper discusses these analysis techniques and presents the results of their application on the CMS FSM system.

  6. Sensometrics methods for descriptive analysis and sorting task. Two applications

    OpenAIRE

    Miranda, Karen

    2013-01-01

    We have presented the results obtained through two sensory methods that are descriptive analysis and categorization. Several statistical methods have been applied to analyze the results: ANOVA; PCA, MCA and MFA.. Sensometrics methods for descriptive analysis and sorting task have to be applied in two cases related to food and beverage industries

  7. Joint Environmental and Economical Analysis of Wastewater Treatment Plants Control Strategies: A Benchmark Scenario Analysis

    Directory of Open Access Journals (Sweden)

    Montse Meneses

    2016-04-01

    Full Text Available In this paper, a joint environmental and economic analysis of different Wastewater Treatment Plant (WWTP control strategies is carried out. The assessment is based on the application of the Life Cycle Assessment (LCA as a method to evaluate the environmental impact and the Benchmark Simulation Model No. 1 (BSM1. The BSM1 is taken as the benchmark scenario used to implement the control strategies. The Effluent Quality Index (EQI and the Overall Cost Index (OCI are two indicators provided by BSM1 and used to evaluate the plant’s performance from the effluent quality and the economic points of view, respectively. This work conducts a combined analysis and assessment of ten different control strategies defined to operate a wastewater treatment plant. This analysis includes the usual economic and performance indexes provided by BSM1 joined with the LCA analysis that determines the environmental impact linked to each one of the considered control strategies. It is shown how to get an overall evaluation of the environmental effects by using a normalized graphical representation that can be easily used to compare control strategies from the environmental impact point of view. The use of only the BSM1 indexes provides an assessment that leads to a clustering of control strategies according to the cost/quality tradeoff they show. Therefore, regarding the cost/quality tradeoff, all strategies in the same group are almost equal and do not provide an indication on how to proceed in order to select the appropriate one. It is therefore shown how the fact of adding a new, complementary, evaluation (LCA based allows either to reinforce a decision that could be taken solely on the basis of the EQI/OCI tradeoff or to select one control strategy among the others.

  8. Orthokeratology to control myopia progression: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Yuan Sun

    Full Text Available To evaluate the clinical treatment effects of orthokeratology to slow the progression of myopia.Several well-designed controlled studies have investigated the effects of orthokeratology in school-aged children. We conducted this meta-analysis to better evaluate the existing evidence. Relevant studies were identified in the Medline and Embase database without language limitations. The main outcomes included axial length and vitreous chamber depth reported as the mean ± standard deviation. The results were pooled and assessed with a fixed-effects model analysis. Subgroup analyses were performed according to geographical location and study design.Of the seven eligible studies, all reported axial length changes after 2 years, while two studies reported vitreous chamber depth changes. The pooled estimates indicated that change in axial length in the ortho-k group was 0.27 mm (95% confidence interval [CI]: 0.22, 0.32 less than the control group. Myopic progression was reduced by approximately 45%. The combined results revealed that the difference in vitreous chamber depth between the two groups was 0.22 mm (95% confidence interval [CI]: 0.14, 0.31. None of the studies reported severe adverse events.The overall findings suggest that ortho-k can slow myopia progression in school-aged children.

  9. Performance Analysis: Work Control Events Identified January - August 2010

    Energy Technology Data Exchange (ETDEWEB)

    De Grange, C E; Freeman, J W; Kerr, C E; Holman, G; Marsh, K; Beach, R

    2011-01-14

    This performance analysis evaluated 24 events that occurred at LLNL from January through August 2010. The analysis identified areas of potential work control process and/or implementation weaknesses and several common underlying causes. Human performance improvement and safety culture factors were part of the causal analysis of each event and were analyzed. The collective significance of all events in 2010, as measured by the occurrence reporting significance category and by the proportion of events that have been reported to the DOE ORPS under the ''management concerns'' reporting criteria, does not appear to have increased in 2010. The frequency of reporting in each of the significance categories has not changed in 2010 compared to the previous four years. There is no change indicating a trend in the significance category and there has been no increase in the proportion of occurrences reported in the higher significance category. Also, the frequency of events, 42 events reported through August 2010, is not greater than in previous years and is below the average of 63 occurrences per year at LLNL since 2006. Over the previous four years, an average of 43% of the LLNL's reported occurrences have been reported as either ''management concerns'' or ''near misses.'' In 2010, 29% of the occurrences have been reported as ''management concerns'' or ''near misses.'' This rate indicates that LLNL is now reporting fewer ''management concern'' and ''near miss'' occurrences compared to the previous four years. From 2008 to the present, LLNL senior management has undertaken a series of initiatives to strengthen the work planning and control system with the primary objective to improve worker safety. In 2008, the LLNL Deputy Director established the Work Control Integrated Project Team to develop the core requirements and graded

  10. Mechanical Recanalization following i.v. Thrombolysis: A Retrospective Analysis regarding Secondary Hemorrhagic Infarctions and Parenchymal Hematomas

    International Nuclear Information System (INIS)

    Introduction. In acute stroke by occlusion of the proximal medial cerebral artery (MCA) or the distal internal carotid artery, intravenous thrombolysis is an established treatment. Another option is mechanical recanalization. It remains unclear if the combination of both methods poses an additional bleeding risk. The aim of this retrospective analysis is to determine the proportion of hemorrhagic infarctions and parenchymal hematomas. Methods. Inclusion criteria were an occlusion of the carotid T or proximal MCA treated with full dose thrombolysis and mechanical recanalization. 31 patients were selected. Devices used were Trevo, Penumbra Aspiration system, Penumbra 3D Retriever, and Revive. The initial control by computed tomography was carried out with a mean delay to intervention of 10.9 hours (SD: 8.5 hours). Results. A slight hemorrhagic infarction (HI1) was observed in 2/31 patients, and a more severe HI2 occurred in two cases. A smaller parenchymal hematoma (PH1) was not seen and a space-occupying PH2 was seen in 2/31 cases. There was no significant difference in the probability of intracranial bleeding after successful (thrombolysis in cerebral infarctions 2b and 3) or unsuccessful recanalization. Conclusion. The proportion of intracranial bleeding using mechanical recanalization following intravenous thrombolysis appears comparable with reports using thrombolysis alone

  11. Risk Analysis in Robust Control -- Making the Case for Probabilistic Robust Control

    CERN Document Server

    Chen, Xinjia; Zhou, Kemin

    2007-01-01

    This paper offers a critical view of the "worst-case" approach that is the cornerstone of robust control design. It is our contention that a blind acceptance of worst-case scenarios may lead to designs that are actually more dangerous than designs based on probabilistic techniques with a built-in risk factor. The real issue is one of modeling. If one accepts that no mathematical model of uncertainties is perfect then a probabilistic approach can lead to more reliable control even if it cannot guarantee stability for all possible cases. Our presentation is based on case analysis. We first establish that worst-case is not necessarily "all-encompassing." In fact, we show that for some uncertain control problems to have a conventional robust control solution it is necessary to make assumptions that leave out some feasible cases. Once we establish that point, we argue that it is not uncommon for the risk of unaccounted cases in worst-case design to be greater than that of the accepted risk in a probabilistic appro...

  12. Control system analysis and synthesis for a six degree-of-freedom universal Force-Reflecting Hand Controller

    Science.gov (United States)

    Handlykken, M.; Turner, T.

    1980-01-01

    A six degree-of-freedom joystick with feedback motors, called the Force-Reflecting Hand Controller (FRHC) is used as control input for the human operator in a teleoperator system. The geometric and dynamic properties of the FRHC are entirely different from those of the manipulator being controlled. The paper discusses the analysis and synthesis of the control loop between the FRHC and the robot arm and examines the necessary position and force transformations. The controller is implemented through a dedicated minicomputer.

  13. ATLAS tile calorimeter cesium calibration control and analysis software

    International Nuclear Information System (INIS)

    An online control system to calibrate and monitor ATLAS Barrel hadronic calorimeter (TileCal) with a movable radioactive source, driven by liquid flow, is described. To read out and control the system an online software has been developed, using ATLAS TDAQ components like DVS (Diagnostic and Verification System) to verify the hardware before running, IS (Information Server) for data and status exchange between networked computers, and other components like DDC (DCS to DAQ Connection), to connect to PVSS-based slow control systems of Tile Calorimeter, high voltage and low voltage. A system of scripting facilities, based on Python language, is used to handle all the calibration and monitoring processes from hardware perspective to final data storage, including various abnormal situations. A QT based graphical user interface to display the status of the calibration system during the cesium source scan is described. The software for analysis of the detector response, using online data, is discussed. Performance of the system and first experience from the ATLAS pit are presented

  14. Bornean orangutan geophagy: analysis of ingested and control soils.

    Science.gov (United States)

    Mahaney, William C; Hancock, Ronald G V; Aufreiter, Susan; Milner, Michael W; Voros, Joan

    2016-02-01

    Geophagy among orangutans is the most poorly documented in contrast to the knowledge of soil-eating practices of other great ape species. Observations of soil consumption by orangutans in the Sungai Wain Forest Preserve (Wanariset) of Borneo are presented, along with physico-mineral-chemical analyses of the ingested soil in an effort to understand what might stimulate the activity. The consumed soils are: light colored, not excessively weathered by normal standards, higher in the clay size fraction relative to controls, and are comprised of a mix of clay minerals without any specificity of 1:1, 2:1 and/or 2:1:1 (Si:Al) species. The geophagic soils contain chlorides below detection limits, effectively eliminating salt as a stimulus. Soil chemical and geochemical analyses confirm that orangutans prefer soils with pH levels near or above 4.0, while controls are consistently lower (pH = 3.5-4.0), a considerable difference in acidity for at least four out of six soils consumed. Geochemical analysis shows Al, Fe and K are high in the consumed vs control samples; higher Al follows from higher clay percentages in the consumed earth. Iron and K may play physiological roles, but Fe is mostly in the ferrous form (Fe(+2)) and may not be readily taken up by the animals. The preferential choice of consumed samples, with pH above 4.0 and higher clay contents, may promote a more beneficial intestinal environment. PMID:25600229

  15. Analysis of rabies in China: transmission dynamics and control.

    Directory of Open Access Journals (Sweden)

    Juan Zhang

    Full Text Available Human rabies is one of the major public-health problems in China. The number of human rabies cases has increased dramatically in the last 15 years, partially due to the poor understanding of the transmission dynamics of rabies and the lack of effective control measures of the disease. In this article, in order to explore effective control and prevention measures we propose a deterministic model to study the transmission dynamics of rabies in China. The model consists of susceptible, exposed, infectious, and recovered subpopulations of both dogs and humans and describes the spread of rabies among dogs and from infectious dogs to humans. The model simulations agree with the human rabies data reported by the Chinese Ministry of Health. We estimate that the basic reproduction number R₀ = 2 for the rabies transmission in China and predict that the number of the human rabies is decreasing but may reach another peak around 2030. We also perform some sensitivity analysis of R₀ in terms of the model parameters and compare the effects of culling and immunization of dogs. Our study demonstrates that (i reducing dog birth rate and increasing dog immunization coverage rate are the most effective methods for controlling rabies in China; and (ii large scale culling of susceptible dogs can be replaced by immunization of them.

  16. Bridging ImmunoGenomic Data Analysis Workflow Gaps (BIGDAWG): An integrated case-control analysis pipeline.

    Science.gov (United States)

    Pappas, Derek J; Marin, Wesley; Hollenbach, Jill A; Mack, Steven J

    2016-03-01

    Bridging ImmunoGenomic Data-Analysis Workflow Gaps (BIGDAWG) is an integrated data-analysis pipeline designed for the standardized analysis of highly-polymorphic genetic data, specifically for the HLA and KIR genetic systems. Most modern genetic analysis programs are designed for the analysis of single nucleotide polymorphisms, but the highly polymorphic nature of HLA and KIR data require specialized methods of data analysis. BIGDAWG performs case-control data analyses of highly polymorphic genotype data characteristic of the HLA and KIR loci. BIGDAWG performs tests for Hardy-Weinberg equilibrium, calculates allele frequencies and bins low-frequency alleles for k×2 and 2×2 chi-squared tests, and calculates odds ratios, confidence intervals and p-values for each allele. When multi-locus genotype data are available, BIGDAWG estimates user-specified haplotypes and performs the same binning and statistical calculations for each haplotype. For the HLA loci, BIGDAWG performs the same analyses at the individual amino-acid level. Finally, BIGDAWG generates figures and tables for each of these comparisons. BIGDAWG obviates the error-prone reformatting needed to traffic data between multiple programs, and streamlines and standardizes the data-analysis process for case-control studies of highly polymorphic data. BIGDAWG has been implemented as the bigdawg R package and as a free web application at bigdawg.immunogenomics.org.

  17. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Science.gov (United States)

    2010-04-01

    ... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FISH AND FISHERY PRODUCTS General... processor shall have and implement a written HACCP plan whenever a hazard analysis reveals one or more...

  18. Analysis and control of issues that delay pharmaceutical projects

    Directory of Open Access Journals (Sweden)

    Nallam Sai Nandeswara Rao

    2015-10-01

    Full Text Available Every project will have certain objectives and service levels to be achieved. The success of a project depends on several dimensions like time, cost/budget, quality, etc. and managing a project involves completing the project within time, within budget and with quality to satisfy the users. Because of the significance of health, pharmaceutical companies realized the importance of project management methods and techniques to make available the life saving drugs in time to the needy patients and hospitals. In literature, there is meager information about pharmaceutical project management oriented towards analysis of issues and factors that contribute to the failure or success of projects. This study attempts to analyse different issues that contribute to time delays in pharmaceutical product-based projects, group them under a finite set of prominent factors and identify remedial measures to control those delays. The feedback of project people of some big pharmaceutical firms of Indian sub-continent was collected for this purpose. Exploratory factor analysis (EFA has been used to reduce the reasons for time delays to a limited number of prominent factors and the EFA model has been further examined by confirmatory factor analysis (CFA for its validation. Remedial measures under each factor of time delays have been gathered and a framework designed to mitigate the time delays in pharmaceutical projects. The derived factors that delay the pharmaceutical projects include resource, monitoring & control, scheduling and planning problems. Important remedial measures like blended resource approach, estimation and forecast of shortage of labour and skills, regular quality training, etc. have been recommended.

  19. Comparative analysis of alcohol control policies in 30 countries.

    Directory of Open Access Journals (Sweden)

    Donald A Brand

    2007-04-01

    Full Text Available BACKGROUND: Alcohol consumption causes an estimated 4% of the global disease burden, prompting governments to impose regulations to mitigate the adverse effects of alcohol. To assist public health leaders and policymakers, the authors developed a composite indicator-the Alcohol Policy Index-to gauge the strength of a country's alcohol control policies. METHODS AND FINDINGS: The Index generates a score based on policies from five regulatory domains-physical availability of alcohol, drinking context, alcohol prices, alcohol advertising, and operation of motor vehicles. The Index was applied to the 30 countries that compose the Organization for Economic Cooperation and Development and regression analysis was used to examine the relationship between policy score and per capita alcohol consumption. Countries attained a median score of 42.4 of a possible 100 points, ranging from 14.5 (Luxembourg to 67.3 (Norway. The analysis revealed a strong negative correlation between score and consumption (r = -0.57; p = 0.001: a 10-point increase in the score was associated with a one-liter decrease in absolute alcohol consumption per person per year (95% confidence interval, 0.4-1.5 l. A sensitivity analysis demonstrated the robustness of the Index by showing that countries' scores and ranks remained relatively stable in response to variations in methodological assumptions. CONCLUSIONS: The strength of alcohol control policies, as estimated by the Alcohol Policy Index, varied widely among 30 countries located in Europe, Asia, North America, and Australia. The study revealed a clear inverse relationship between policy strength and alcohol consumption. The Index provides a straightforward tool for facilitating international comparisons. In addition, it can help policymakers review and strengthen existing regulations aimed at minimizing alcohol-related harm and estimate the likely impact of policy changes.

  20. Detection of the East and West African kdr mutation in Anopheles gambiae and Anopheles arabiensis from Uganda using a new assay based on FRET/Melt Curve analysis

    Directory of Open Access Journals (Sweden)

    Backeljau Thierry

    2006-02-01

    Full Text Available Abstract Background Appropriate monitoring of vector resistance to insecticides is an integral component of planning and evaluation of insecticide use in malaria control programmes. The malaria vectors Anopheles gambiae s.s. and Anopheles arabiensis have developed resistance to pyrethroid insecticides as a result of a mechanism conferring reduced nervous system sensitivity, better known as knockdown resistance (kdr. In An. gambiae s.s. and An. arabiensis, two different substitutions in the para-type sodium channel, a L1014F substitution common in West Africa and a L1014S replacement found in Kenya, are linked with kdr. Two different allele-specific polymerase chain reactions (AS-PCR are needed to detect these known kdr mutations. However, these AS-PCR assays rely on a single nucleotide polymorphism mismatch, which can result in unreliable results. Methods Here, a new assay for the detection of knockdown resistance in An. gambiae s.s. and An. arabiensis based on Fluorescence Resonance Energy Transfer/Melt Curve analysis (FRET/MCA is presented and compared with the existing assays. Results The new FRET/MCA method has the important advantage of detecting both kdr alleles in one assay. Moreover, results show that the FRET/MCA is more reliable and more sensitive than the existing AS-PCR assays and is able to detect new genotypes. By using this technique, the presence of the East African kdr mutation (L1014S is shown for the first time in An. arabiensis specimens from Uganda. In addition, a new kdr genotype is reported in An. gambiae s.s. from Uganda, where four An. gambiae s.s. mosquitoes possess both, the West (L1014F and East (L1014S African kdr allele, simultaneously. Conclusion The presence of both kdr mutations in the same geographical region shows the necessity of a reliable assay that enables to detect both mutations in one single assay. Hence, this new assay based on FRET/MCA will improve the screening of the kdr frequencies in An. gambiae s

  1. How to determine control of growth rate in a chemostat. Using metabolic control analysis to resolve the paradox

    DEFF Research Database (Denmark)

    Snoep, Jacky L.; Jensen, Peter Ruhdal; Groeneveld, Philip;

    1994-01-01

    how, paradoxically, one can determine control of growth rate, of growth yield and of other fluxes in a chemostat. We develop metabolic control analysis for the chemostat. this analysis does not depend on the particular way in which specific growth rate varies with the concentration of the growth...

  2. Spatial control of groundwater contamination, using principal component analysis

    Indian Academy of Sciences (India)

    N Subba Rao

    2014-06-01

    A study on the geochemistry of groundwater was carried out in a river basin of Andhra Pradesh to probe into the spatial controlling processes of groundwater contamination, using principal component analysis (PCA). The PCA transforms the chemical variables, pH, EC, Ca2+, Mg2+, Na+, K+, HCO$^{−}_{3}$, Cl−, SO$^{2−}_{4}$, NO$^{−}_{3}$ and F−, into two orthogonal principal components (PC1 and PC2), accounting for 75% of the total variance of the data matrix. PC1 has high positive loadings of EC, Na+, Cl−, SO$^{2−}_{4}$, Mg2+ and Ca2+, representing a salinity controlled process of geogenic (mineral dissolution, ion exchange, and evaporation), anthropogenic (agricultural activities and domestic wastewaters), and marine (marine clay) origin. The PC2 loadings are highly positive for HCO$^{−}_{3}$, F−, pH and NO$^{−}_{3}$, attributing to the alkalinity and pollution controlled processes of geogenic and anthropogenic origins. The PC scores reflect the change of groundwater quality of geogenic origin from upstream to downstream area with an increase in concentration of chemical variables, which is due to anthropogenic and marine origins with varying topography, soil type, depth of water levels, and water usage. Thus, the groundwater quality shows a variation of chemical facies from Na+ > Ca2+ > Mg2+ > K+: HCO$^{−}_{3}$ > Cl− > SO$^{2−}_{4}$ > NO$^{−}_{3}$ > F− at high topography to Na+ > Mg2+ > Ca2+ > K+: Cl− > HCO$^{−}_{3}$ > SO$^{2−}_{4}$ > NO$^{−}_{3}$ > F− at low topography. With PCA, an effective tool for the spatial controlling processes of groundwater contamination, a subset of explored wells is indexed for continuous monitoring to optimize the expensive effort.

  3. Austrian meat: Authenticity control by stable isotope analysis

    International Nuclear Information System (INIS)

    Full text: The EU has declared that all foodstuff must be able to be traced back from 'fork to farm' to increase the safety of food and the confidence of the consumers in food quality and safety. Additionally, several incidents of 'food diseases and scandals' related with meat (e.g.: BSE, foot and mouth disease, antibiotics abuse, avian flu, etc.) have demonstrated the necessity to trace back the origin of meat, to be able to locate sources of infection/mismanagement. Besides the conventional method of the control of documentation there is the possibility of control of origin by analysing the isotopic composition of meat and herewith controlling the questioned good itself. Stable isotope ratios of the elements HCNOS are varying geographically due to different environmental conditions (e.g.: climate, geology, soil, altitude, geography, etc.) thus every region possesses an individual pattern. The isotopic pattern is imprinted on plants and animals growing in a certain region, and therefore analysis of the stable isotope pattern can allow the identification of agricultural goods from different regions. For the control of origin of Austrian meat about 500 beef and 500 pork samples have been collected from slaughterhouses and were analysed for the isotopic composition of carbon, nitrogen, oxygen and sulphur and compared with the isotopic composition of meat samples from neighbouring countries. As Austria, despite being a small country, is very heterogeneous in its environmental conditions, thus there are significant differences in the isotopic patterns of individual Austrian provinces. The isotopic signature of meat samples from neighbouring countries can overlap with the 'Austrian isotope pattern' due to similar environmental conditions. However, a correct statistical classification has been achieved for 80% and 84% of the analysed beef and pork samples, respectively. If the declared origin of meat can be pinned down to an Austrian province, the discrimination power of

  4. Computer Models for IRIS Control System Transient Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Gary D. Storrick; Bojan Petrovic; Luca Oriani

    2007-01-31

    This report presents results of the Westinghouse work performed under Task 3 of this Financial Assistance Award and it satisfies a Level 2 Milestone for the project. Task 3 of the collaborative effort between ORNL, Brazil and Westinghouse for the International Nuclear Energy Research Initiative entitled “Development of Advanced Instrumentation and Control for an Integrated Primary System Reactor” focuses on developing computer models for transient analysis. This report summarizes the work performed under Task 3 on developing control system models. The present state of the IRIS plant design – such as the lack of a detailed secondary system or I&C system designs – makes finalizing models impossible at this time. However, this did not prevent making considerable progress. Westinghouse has several working models in use to further the IRIS design. We expect to continue modifying the models to incorporate the latest design information until the final IRIS unit becomes operational. Section 1.2 outlines the scope of this report. Section 2 describes the approaches we are using for non-safety transient models. It describes the need for non-safety transient analysis and the model characteristics needed to support those analyses. Section 3 presents the RELAP5 model. This is the highest-fidelity model used for benchmark evaluations. However, it is prohibitively slow for routine evaluations and additional lower-fidelity models have been developed. Section 4 discusses the current Matlab/Simulink model. This is a low-fidelity, high-speed model used to quickly evaluate and compare competing control and protection concepts. Section 5 describes the Modelica models developed by POLIMI and Westinghouse. The object-oriented Modelica language provides convenient mechanisms for developing models at several levels of detail. We have used this to develop a high-fidelity model for detailed analyses and a faster-running simplified model to help speed the I&C development process

  5. Computer Models for IRIS Control System Transient Analysis

    International Nuclear Information System (INIS)

    This report presents results of the Westinghouse work performed under Task 3 of this Financial Assistance Award and it satisfies a Level 2 Milestone for the project. Task 3 of the collaborative effort between ORNL, Brazil and Westinghouse for the International Nuclear Energy Research Initiative entitled 'Development of Advanced Instrumentation and Control for an Integrated Primary System Reactor' focuses on developing computer models for transient analysis. This report summarizes the work performed under Task 3 on developing control system models. The present state of the IRIS plant design--such as the lack of a detailed secondary system or I and C system designs--makes finalizing models impossible at this time. However, this did not prevent making considerable progress. Westinghouse has several working models in use to further the IRIS design. We expect to continue modifying the models to incorporate the latest design information until the final IRIS unit becomes operational. Section 1.2 outlines the scope of this report. Section 2 describes the approaches we are using for non-safety transient models. It describes the need for non-safety transient analysis and the model characteristics needed to support those analyses. Section 3 presents the RELAP5 model. This is the highest-fidelity model used for benchmark evaluations. However, it is prohibitively slow for routine evaluations and additional lower-fidelity models have been developed. Section 4 discusses the current Matlab/Simulink model. This is a low-fidelity, high-speed model used to quickly evaluate and compare competing control and protection concepts. Section 5 describes the Modelica models developed by POLIMI and Westinghouse. The object-oriented Modelica language provides convenient mechanisms for developing models at several levels of detail. We have used this to develop a high-fidelity model for detailed analyses and a faster-running simplified model to help speed the I and C development process. Section

  6. Root cause analysis to support infection control in healthcare premises.

    Science.gov (United States)

    Venier, A-G

    2015-04-01

    Infection control teams (ICTs) seek to prevent healthcare-associated infections (HCAIs). They undertake surveillance and prevention, promote safety and quality of care, and evaluate and manage risk. Root cause analysis (RCA) can support this work but is not widely used by ICTs. This paper describes how ICTs can use RCA to enhance their day-to-day work. Many different tools and methods exist for RCA. Its primary aim is to identify the factors that have led to HCAI, but RCA can also be used for near-misses. A team effort and multidisciplinary work are usually required. Published accounts and personal experience in the field indicate that an ICT that correctly uses RCA implements more effective prevention measures, improves practice and collaborative working, enhances teamwork, and reduces the risk of HCAI. RCA should be promoted among ICTs because it adds value to their work and helps to develop a hospital culture that anticipates and pre-empts problems. PMID:25634490

  7. Optical polarimeter based on Fourier analysis and electronic control

    International Nuclear Information System (INIS)

    In this paper, we show the design and implementation of an optical polarimeter using electronic control and the Fourier analysis. The polarimeter prototype will be used as a main tool for the students of the Universidad Popular del Cesar that belong to the following university programs: Electronics engineering (optoelectronics area), Math and Physics degree and the Master in Physics Sciences, in order to learning the theory and experimental aspects of the state of optical polarization via the Stokes vector measurement. Using the electronic polarimeter proposed in this paper, the students will be able to observe (in an optical bench) and understand the different interactions of the states of optical polarization when the optical waves pass through to the polarizers and retarder waves plates. The electronic polarimeter has a software that captures the optical intensity measurement and evaluates the Stokes vector. (Author)

  8. Quality control of coins mint using PIXE and RBS analysis

    Science.gov (United States)

    Roumie, M.; Nsouli, B.; Chalhoub, G.; Hamdan, M.

    2010-06-01

    PIXE and RBS analysis is used to investigate the elemental content of modern Lebanese coins, in order to control their minting quality. The coins of interest were 100, 250 and 500 Lebanese Lira (LL), which are mainly bulky metals with or without coated layer. Using 3 MeV protons, proton induced X-ray emission PIXE identified and quantified elements while Rutherford backscattering spectrometry RBS checked the thickness of the coated layer. Indeed, the combination of PIXE and RBS provides a powerful tool to investigate the elemental composition of coins, either modern or ancient. In addition, the experimental protocol was checked by analyzing some other coins of known composition, such as 1-euro and 2-euro.

  9. Oil and hydrocarbon spills, modelling, analysis and control

    International Nuclear Information System (INIS)

    The transport of oil from production centres to worldwide markets is usually carried out by tankers and pipelines. With the occurrence of many oil spills in recent years has come a growing awareness of the need for prevention measures and makes oil spill research one of the most difficult challenges in the present day. At the first International Conference on oil and hydrocarbon spills, modelling analysis and control, held in July 1998, 32 papers were presented to researchers, engineers and managers from all over the world. A wide range of subjects, including applied modelling techniques, contingency and response plans, resource rehabilitation methods, laboratory and field experiments, and case studies were presented. The papers are abstracted here. (UK)

  10. Comparative Analysis of Congestion Control Algorithms Using ns-2

    CERN Document Server

    Patel, Sanjeev; Garg, Arjun; Mehrotra, Prateek; Chhabra, Manish

    2012-01-01

    In order to curtail the escalating packet loss rates caused by an exponential increase in network traffic, active queue management techniques such as Random Early Detection (RED) have come into picture. Flow Random Early Drop (FRED) keeps state based on instantaneous queue occupancy of a given flow. FRED protects fragile flows by deterministically accepting flows from low bandwidth connections and fixes several shortcomings of RED by computing queue length during both arrival and departure of the packet. Stochastic Fair Queuing (SFQ) ensures fair access to network resources and prevents a busty flow from consuming more than its fair share. In case of (Random Exponential Marking) REM, the key idea is to decouple congestion measure from performance measure (loss, queue length or delay). Stabilized RED (SRED) is another approach of detecting nonresponsive flows. In this paper, we have shown a comparative analysis of throughput, delay and queue length for the various congestion control algorithms RED, SFQ and REM...

  11. Model analysis of mechanisms controlling pneumatic soil vapor extraction.

    Science.gov (United States)

    Høier, C K; Sonnenborg, T O; Jensen, K H; Gudbjerg, J

    2009-01-26

    The efficiency of traditional soil venting or soil vapor extraction (SVE) highly depends on the architecture of the subsurface because imposed advective air flow tends to bypass low-permeable contaminated areas. Pneumatic SVE is a technique developed to enhance remediation efficiency of heterogeneous soils by enforcing large fluctuating pressure fronts through the contaminated area. Laboratory experiments have suggested that pneumatic SVE considerably improves the recovery rate from low-permeable units. We have analyzed the experimental results using a numerical code and quantified the physical processes controlling the functioning of the method. A sensitivity analysis for selected boundary conditions, initial conditions and parameters was carried out to examine how the method behaves under conditions different from the experimental set-up. The simulations show that at the laboratory level the pneumatic venting technology is superior to the traditional technique, and that the method is particularly efficient in cases where large permeability contrasts exist between soil units in the subsurface. PMID:19004522

  12. Cost-effectiveness analysis in Chagas' disease vectors control interventions

    Directory of Open Access Journals (Sweden)

    A. M. Oliveira Filho

    1989-01-01

    Full Text Available After a large scale field trial performed in central Brazil envisaging the control of Chagas' disease vectors in an endemic area colonized by Triatoma infestans and T. sordida the cost-effectiveness analysis for each insecticide/formulation was performed. It considered the operational costs and the prices of insecticides and formulations, related to the activity and persistence of each one. The end point was considered to be less than 90% of domicilliary unitis (house + annexes free of infestation. The results showed good cost-effectiveness for a slow-release emulsifiable suspension (SRES based on PVA and containing malathion as active ingredient, as well as for the pyrethroids tested in this assay-cyfluthrin, cypermethrin, deltamethrin and permethrin.

  13. Computational Analysis of the Hypothalamic Control of Food Intake.

    Science.gov (United States)

    Tabe-Bordbar, Shayan; Anastasio, Thomas J

    2016-01-01

    Food-intake control is mediated by a heterogeneous network of different neural subtypes, distributed over various hypothalamic nuclei and other brain structures, in which each subtype can release more than one neurotransmitter or neurohormone. The complexity of the interactions of these subtypes poses a challenge to understanding their specific contributions to food-intake control, and apparent consistencies in the dataset can be contradicted by new findings. For example, the growing consensus that arcuate nucleus neurons expressing Agouti-related peptide (AgRP neurons) promote feeding, while those expressing pro-opiomelanocortin (POMC neurons) suppress feeding, is contradicted by findings that low AgRP neuron activity and high POMC neuron activity can be associated with high levels of food intake. Similarly, the growing consensus that GABAergic neurons in the lateral hypothalamus suppress feeding is contradicted by findings suggesting the opposite. Yet the complexity of the food-intake control network admits many different network behaviors. It is possible that anomalous associations between the responses of certain neural subtypes and feeding are actually consistent with known interactions, but their effect on feeding depends on the responses of the other neural subtypes in the network. We explored this possibility through computational analysis. We made a computer model of the interactions between the hypothalamic and other neural subtypes known to be involved in food-intake control, and optimized its parameters so that model behavior matched observed behavior over an extensive test battery. We then used specialized computational techniques to search the entire model state space, where each state represents a different configuration of the responses of the units (model neural subtypes) in the network. We found that the anomalous associations between the responses of certain hypothalamic neural subtypes and feeding are actually consistent with the known structure

  14. Introduction to time-delay systems analysis and control

    CERN Document Server

    Fridman, Emilia

    2014-01-01

    The beginning of the 21st century can be characterized as the ”time-delay boom” leading to numerous important results. The purpose of this book is two-fold, to familiarize the non-expert reader with time-delay systems and to provide a systematic treatment of modern ideas and techniques for experts. This book is based on the course ”Introduction to time-delay systems” for graduate students in Engineering and Applied Mathematics that the author taught in Tel Aviv University in 2011-2012 and 2012-2013 academic years. The sufficient background to follow most of the material are the undergraduate courses in mathematics and an introduction to control. The book leads the reader from some basic classical results on time-delay systems to recent developments on Lyapunov-based analysis and design with applications to the hot topics of sampled-data and network-based control. The objective is to provide useful tools that will allow the reader not only to apply the existing methods, but also to develop new ones. It...

  15. Cognitive Systems Modeling and Analysis of Command and Control Systems

    Science.gov (United States)

    Norlander, Arne

    2012-01-01

    Military operations, counter-terrorism operations and emergency response often oblige operators and commanders to operate within distributed organizations and systems for safe and effective mission accomplishment. Tactical commanders and operators frequently encounter violent threats and critical demands on cognitive capacity and reaction time. In the future they will make decisions in situations where operational and system characteristics are highly dynamic and non-linear, i.e. minor events, decisions or actions may have serious and irreversible consequences for the entire mission. Commanders and other decision makers must manage true real time properties at all levels; individual operators, stand-alone technical systems, higher-order integrated human-machine systems and joint operations forces alike. Coping with these conditions in performance assessment, system development and operational testing is a challenge for both practitioners and researchers. This paper reports on research from which the results led to a breakthrough: An integrated approach to information-centered systems analysis to support future command and control systems research development. This approach integrates several areas of research into a coherent framework, Action Control Theory (ACT). It comprises measurement techniques and methodological advances that facilitate a more accurate and deeper understanding of the operational environment, its agents, actors and effectors, generating new and updated models. This in turn generates theoretical advances. Some good examples of successful approaches are found in the research areas of cognitive systems engineering, systems theory, and psychophysiology, and in the fields of dynamic, distributed decision making and naturalistic decision making.

  16. Analysis of Control Strategies for Diode Clamped Multilevel Inverter

    Directory of Open Access Journals (Sweden)

    C. R. Balamurugan

    2013-05-01

    Full Text Available This paper presents the comparison of various Pulse Width Modulation (PWM strategies for the three phase Diode Clamped Multi Level Inverter (DCMLI. The main contribution of this paper is the proposal of new modulation schemes with Variable Amplitude (VA and various new schemes adopting the constant switching frequency and also variable switching frequency multicarrier control freedom degree combination concepts are developed and simulated for the chosen three phase DCMLI. The three phase DCMLI, is controlled in this paper with Sinusoidal PWM (SPWM reference along with triangular carriers and analysis is made among both without carrier overlapping and with Carrier Overlapping (CO techniques to choose the better strategy by performing simulation using MATLAB-SIMULINK. The variation of Total Harmonic Distortion (THD and fundamental RMS output voltage is observed for various modulation indices. It is observed that among the various equal amplitude PWM strategies, COPWM-C provides less THD and higher RMS voltage. It is recognized that among the various variable amplitude PWM strategies, VACOPWM-C provides less THD and VACOPWM-B provides higher RMS voltage. By comparing the equal amplitude PWM strategies with the variable amplitude PWM strategies it is inferred that VACOPWM-C provides less THD and VACOPWM-B provides higher RMS voltage. It is also inferred that carrier overlapping techniques provides better results compared to the without carrier overlapping techniques.

  17. Modal cost analysis for linear matrix-second-order systems

    Science.gov (United States)

    Skelton, R. E.; Hughes, P. C.

    1980-01-01

    Reduced models and reduced controllers for systems governed by matrix-second-order differential equations are obtained by retaining those modes which make the largest contributions to quadratic control objectives. Such contributions, expressed in terms of modal data, used as mode truncation criteria, allow the statement of the specific control objectives to influence the early model reduction from very high order models which are available, for example, from finite element methods. The relative importance of damping, frequency, and eigenvector in the mode truncation decisions are made explicit for each of these control objectives: attitude control, vibration suppression and figure control. The paper also shows that using modal cost analysis (MCA) on the closed loop modes of the optimally controlled system allows the construction of reduced control policies which feedback only those closed loop modal coordinates which are most critical to the quadratic control performance criterion. In this way, the modes which should be controlled (and hence the modes which must be observable by choice of measurements), are deduced from truncations of the optimal controller.

  18. Uncertainty Modeling for Structural Control Analysis and Synthesis

    Science.gov (United States)

    Campbell, Mark E.; Crawley, Edward F.

    1996-01-01

    The development of an accurate model of uncertainties for the control of structures that undergo a change in operational environment, based solely on modeling and experimentation in the original environment is studied. The application used throughout this work is the development of an on-orbit uncertainty model based on ground modeling and experimentation. A ground based uncertainty model consisting of mean errors and bounds on critical structural parameters is developed. The uncertainty model is created using multiple data sets to observe all relevant uncertainties in the system. The Discrete Extended Kalman Filter is used as an identification/parameter estimation method for each data set, in addition to providing a covariance matrix which aids in the development of the uncertainty model. Once ground based modal uncertainties have been developed, they are localized to specific degrees of freedom in the form of mass and stiffness uncertainties. Two techniques are presented: a matrix method which develops the mass and stiffness uncertainties in a mathematical manner; and a sensitivity method which assumes a form for the mass and stiffness uncertainties in macroelements and scaling factors. This form allows the derivation of mass and stiffness uncertainties in a more physical manner. The mass and stiffness uncertainties of the ground based system are then mapped onto the on-orbit system, and projected to create an analogous on-orbit uncertainty model in the form of mean errors and bounds on critical parameters. The Middeck Active Control Experiment is introduced as experimental verification for the localization and projection methods developed. In addition, closed loop results from on-orbit operations of the experiment verify the use of the uncertainty model for control analysis and synthesis in space.

  19. Economic Analysis of Vaccination Strategies for PRRS Control.

    Directory of Open Access Journals (Sweden)

    Daniel C L Linhares

    Full Text Available Porcine reproductive and respiratory syndrome virus (PRRSv is a swine-specific pathogen that causes significant increases in production costs. When a breeding herd becomes infected, in an attempt to hasten control and elimination of PRRSv, some veterinarians have adopted a strategy called load-close-expose which consists of interrupting replacement pig introductions into the herd for several weeks (herd closure and exposing the whole herd to a replicating PRRSv to boost herd immunity. Either modified-live virus (MLV vaccine or live field-virus inoculation (FVI is used. This study consisted of partial budget analyses to compare MLV to FVI as the exposure method of load-close-expose program to control and eliminate PRRSv from infected breeding herds, and secondly to estimate benefit / cost of vaccinating sow herds preventatively. Under the assumptions used in this study, MLV held economic advantage over FVI. However, sensitivity analysis revealed that decreasing margin over variable costs below $ 47.32, or increasing PRRSv-attributed cost above $18.89 or achieving time-to-stability before 25 weeks resulted in advantage of FVI over MLV. Preventive vaccination of sow herds was beneficial when the frequency of PRRSv infection was at least every 2.1 years. The economics of preventative vaccination was minimally affected by cost attributed to field-type PRRSv infection on growing pigs or by the breeding herd productivity level. The models developed and described in this paper provide valuable tools to assist veterinarians in their efforts to control PRRSv.

  20. HPLC-MS technique for radiopharmaceuticals analysis and quality control

    Science.gov (United States)

    Macášek, F.; Búriová, E.; Brúder, P.; Vera-Ruiz, H.

    2003-01-01

    Potentialities of liquid chromatography with mass spectrometric detector (MSD) were investigated with the objective of quality control of radiopharmaceuticals; 2-deoxy-2-[18F]fluoro-D-glucose (FDG) being an example. Screening of suitable MSD analytical lines is presented. Mass-spectrometric monitoring of acetonitrile— aqueous ammonium formate eluant by negatively charged FDG.HCO2 - ions enables isotope analysis (specific activity) of the radiopharmaceutical at m/z 227 and 226. Kryptofix® 222 provides an intense MSD signal of the positive ion associated with NH4 + at m/z 394. Expired FDG injection samples contain decomposition products from which at least one labelled by 18F and characterised by signal of negative ions at m/z 207 does not correspond to FDG fragments but to C5 decomposition products. A glucose chromatographic peak, characterised by m/z 225 negative ion is accompanied by a tail of a component giving a signal of m/z 227, which can belong to [18O]glucose; isobaric sorbitol signals were excluded but FDG-glucose association occurs in the co-elution of separation of model mixtures. The latter can actually lead to a convoluted chromatographic peak, but the absence of 18F makes this inconsistent. Quantification and validation of the FDG component analysis is under way.

  1. Is there a place for hair analysis in doping controls?

    Science.gov (United States)

    Rivier, L

    2000-01-10

    . The frequency of hair cutting and short hair cuts necessary to gain speed in specific sports like swimming are other critical factors. On the other hands, irregular hair growth, associated with the washout effect through multiple washing and staining processes over expanded time intervals can cause concentrating or diluting effects. So far, a minority of prohibited substances could be detected in scalp hair with the sensitivity and specificity required in the context of the sport's activities. From the above, clear limitations of the usefulness of hair analysis in doping control analysis are obvious until a lot more data relevant to this particular field have been collected. PMID:10689583

  2. Analysis of one dimensional and two dimensional fuzzy controllers

    Institute of Scientific and Technical Information of China (English)

    Ban Xiaojun; Gao Xiaozhi; Huang Xianlin; Wu Tianbao

    2006-01-01

    The analytical structures and the corresponding mathematical properties of the one dimensional and two dimensional fuzzy controllers are first investigated in detail.The nature of these two kinds of fuzzy controllers is next probed from the perspective of control engineering. For the one dimensional fuzzy controller, it is concluded that this controller is a combination of a saturation element and a nonlinear proportional controller, and the system that employs the one dimensional fuzzy controller is the combination of an open-loop control system and a closedloop control system. For the latter case, it is concluded that it is a hybrid controller, which comprises the saturation part, zero-output part, nonlinear derivative part, nonlinear proportional part, as well as nonlinear proportional-derivative part, and the two dimensional fuzzy controller-based control system is a loop-varying system with varying number of control loops.

  3. Analysis of N-qubit perfectly controlled teleportation schemes from the controller's point of view

    OpenAIRE

    Li, Xi-Han; Ghose, Shohini

    2014-01-01

    We quantitatively analyze and evaluate the controller's power in $N$-qubit controlled teleportation schemes. We calculate the minimum control power required to ensure the controller's authority such that the teleportation fidelity without the controller's permission is no more than the classical bound. We revisit several typical controlled teleportation schemes from the controller's point of view and evaluate the control power in these schemes. We find that for teleporting arbitrary N-qubit s...

  4. Polynomial fuzzy model-based control systems stability analysis and control synthesis using membership function dependent techniques

    CERN Document Server

    Lam, Hak-Keung

    2016-01-01

    This book presents recent research on the stability analysis of polynomial-fuzzy-model-based control systems where the concept of partially/imperfectly matched premises and membership-function dependent analysis are considered. The membership-function-dependent analysis offers a new research direction for fuzzy-model-based control systems by taking into account the characteristic and information of the membership functions in the stability analysis. The book presents on a research level the most recent and advanced research results, promotes the research of polynomial-fuzzy-model-based control systems, and provides theoretical support and point a research direction to postgraduate students and fellow researchers. Each chapter provides numerical examples to verify the analysis results, demonstrate the effectiveness of the proposed polynomial fuzzy control schemes, and explain the design procedure. The book is comprehensively written enclosing detailed derivation steps and mathematical derivations also for read...

  5. Analysis of the effect on control systems of order variation for fractional-order PIλ Dμ controllers

    Institute of Scientific and Technical Information of China (English)

    ZENG Qing-shan; CAO Guang-yi; ZHU Xin-jian

    2005-01-01

    This paper is concerned with fractional-order PIλDμcontrollers. The definitions and properties of fracti-onal calculus are introduced. The mathematical descriptions of a fractional-order controller and fractionalorder control systems are outlined. The effects on control systems of order variation for fractional-order Piλ Dμ controllers are investigated by qualitative analysis and simulation. The conclusions and simulation examples are given. The results show the fractional-order PIλDμ controller is not sensitive to variation of its order.

  6. Automation of low energy gamma spectrometric analysis of mineral samples

    International Nuclear Information System (INIS)

    An interface device to perform the automatic operation of a multichannel analyser CANBERRA S30 from a COMODORE 64 microcomputer was developed. The interface also allows the manual control of the MCA and fulfills the requirements of low cost and simplicity

  7. Analysis and Optimal Condition of the Rear-Sound-Aided Control Source in Active Noise Control

    Directory of Open Access Journals (Sweden)

    Karel Kreuter

    2011-01-01

    Full Text Available An active noise control scenario of simple ducts is considered. The previously suggested technique of using an single loudspeaker and its rear sound to cancel the upstream sound is further examined and compared to the bidirectional solution in order to give theoretical proof of its advantage. Firstly, a model with a new approach for taking damping effects into account is derived based on the electrical transmission line theory. By comparison with the old model, the new approach is validated, and occurring differences are discussed. Moreover, a numerical application with the consideration of damping is implemented for confirmation. The influence of the rear sound strength on the feedback-path system is investigated, and the optimal condition is determined. Finally, it is proven that the proposed source has an advantage of an extended phase lag and a time delay in the feedback-path system by both frequency-response analysis and numerical calculation of the time response.

  8. Dynamic Curvature Steering Control for Autonomous Vehicle: Performance Analysis

    Science.gov (United States)

    Aizzat Zakaria, Muhammad; Zamzuri, Hairi; Amri Mazlan, Saiful

    2016-02-01

    This paper discusses the design of dynamic curvature steering control for autonomous vehicle. The lateral control and longitudinal control are discussed in this paper. The controller is designed based on the dynamic curvature calculation to estimate the path condition and modify the vehicle speed and steering wheel angle accordingly. In this paper, the simulation results are presented to show the capability of the controller to track the reference path. The controller is able to predict the path and modify the vehicle speed to suit the path condition. The effectiveness of the controller is shown in this paper whereby identical performance is achieved with the benchmark but with extra curvature adaptation capabilites.

  9. Exact Controllability and Asymptotic Analysis for Shallow Shells

    Institute of Scientific and Technical Information of China (English)

    S. KAIZU; N. SABU

    2007-01-01

    The authors consider the exact controllability of the vibrations of a thin shallow shell, of thickness 2ε with controls imposed on the lateral surface and at the top and bottom of the shell. Apart from proving the existence of exact controls, it is shown that the solutions of the three dimensional exact controllability problems converge, as the thickness of the shell goes to zero, to the solution of an exact controllability problem in two dimensions.

  10. Analysis and Design of Heat Energy Control System

    OpenAIRE

    Adu Poku, Daniel

    2011-01-01

    As technology progresses, many kinds of control systems are being developed using the concept of control theory to keep pace with modern day application requirements, ranging from simple to sophisticated types of control system. Control systems can be found in different practical application such as biological systems, robotic systems, space applications, home appliances and so many more. The thesis has been carried out to analyze the fundamental theory of control systems and its main el...

  11. Bifurcation Analysis and Chaos Control in a Discrete Epidemic System

    Directory of Open Access Journals (Sweden)

    Wei Tan

    2015-01-01

    Full Text Available The dynamics of discrete SI epidemic model, which has been obtained by the forward Euler scheme, is investigated in detail. By using the center manifold theorem and bifurcation theorem in the interior R+2, the specific conditions for the existence of flip bifurcation and Neimark-Sacker bifurcation have been derived. Numerical simulation not only presents our theoretical analysis but also exhibits rich and complex dynamical behavior existing in the case of the windows of period-1, period-3, period-5, period-6, period-7, period-9, period-11, period-15, period-19, period-23, period-34, period-42, and period-53 orbits. Meanwhile, there appears the cascade of period-doubling 2, 4, 8 bifurcation and chaos sets from the fixed point. These results show the discrete model has more richer dynamics compared with the continuous model. The computations of the largest Lyapunov exponents more than 0 confirm the chaotic behaviors of the system x→x+δ[rN(1-N/K-βxy/N-(μ+mx], y→y+δ[βxy/N-(μ+dy]. Specifically, the chaotic orbits at an unstable fixed point are stabilized by using the feedback control method.

  12. Collaborative human-machine analysis using a controlled natural language

    Science.gov (United States)

    Mott, David H.; Shemanski, Donald R.; Giammanco, Cheryl; Braines, Dave

    2015-05-01

    A key aspect of an analyst's task in providing relevant information from data is the reasoning about the implications of that data, in order to build a picture of the real world situation. This requires human cognition, based upon domain knowledge about individuals, events and environmental conditions. For a computer system to collaborate with an analyst, it must be capable of following a similar reasoning process to that of the analyst. We describe ITA Controlled English (CE), a subset of English to represent analyst's domain knowledge and reasoning, in a form that it is understandable by both analyst and machine. CE can be used to express domain rules, background data, assumptions and inferred conclusions, thus supporting human-machine interaction. A CE reasoning and modeling system can perform inferences from the data and provide the user with conclusions together with their rationale. We present a logical problem called the "Analysis Game", used for training analysts, which presents "analytic pitfalls" inherent in many problems. We explore an iterative approach to its representation in CE, where a person can develop an understanding of the problem solution by incremental construction of relevant concepts and rules. We discuss how such interactions might occur, and propose that such techniques could lead to better collaborative tools to assist the analyst and avoid the "pitfalls".

  13. Novel analysis of Petri-net-based controllers by means of TCT implementation tool of supervisory control theory

    Directory of Open Access Journals (Sweden)

    Murat Uzam

    2010-09-01

    Full Text Available The control of discrete event systems (DES has been widely studied in the past two decades. Finite-state automata (FSA and Petri nets (PN are the two principal modelling formalisms for this study. Supervisory control theory (SCT, based on language and FSA concepts, is a well established framework for the study of discrete event control systems (DECS. PN-based approaches to the control design have been considered as an alternative framework. In the PN-based control of DES, given an uncontrolled PN model of a system and a set of specifications, a PN-based controller consisting of monitors (control places is synthesised to solve the problem. In general, forbidden-state specifications are considered. Another heavily studied specification is to obtain the live system behaviour (non-blockingness in SCT terminology for a given PN model by computing a PN-based controller. Unfortunately, PN-based analysis tools cannot deal with uncontrollable transitions. Therefore, to date there is no general technique for the correctness analysis of the computed PN-based controllers. This paper proposes a novel and general methodology to carry out the correctness analysis for the computed PN-based controllers by using the TCT implementation tool of SCT. Three examples are considered for illustration.

  14. Quantitative analysis of distributed control paradigms of robot swarms

    DEFF Research Database (Denmark)

    Ngo, Trung Dung

    2010-01-01

    Given a task of designing controller for mobile robots in swarms, one might wonder which distributed control paradigms should be selected. Until now, paradigms of robot controllers have been within either behaviour based control or neural network based control, which have been recognized as two...... describe the physical and simulated robots, experiment scenario, and experiment setup. Third, we present our robot controllers based on behaviour based and neural network based paradigms. Fourth, we graphically show their experiment results and quantitatively analyse the results in comparison of the two...

  15. Non-target effects of the microbial control agents Pseudomonas fluorescens DR54 and Clonostachys rosea IK726 in soils cropped with barley followed by sugar beet

    DEFF Research Database (Denmark)

    Johansen, Anders; Knudsen, Inge M.B.; Binnerup, Svend J.;

    2005-01-01

    Non-target effects of a bacterial (Pseudomonas fluorescens DR54) and a fungal (Clonostachys rosea IK726) microbial control agent (MCA), on the indigenous microbiota in bulk soil and rhizosphere of barley, and subsequent a sugar beet crop, were studied in a greenhouse experiment. MCAs were...... by a factor of 106 and 20, respectively, and DR54 showed a short-lasting growth increase in the sugar beet rhizosphere. In general, the non-target effects were small and transient. IK726 seemed to have general stimulating effects on soil enzyme activity and the soil microbiota, and resulted in a significant...... to be suitable for in situ monitoring of MCA non-target effects on the soil microbiota, but should be combined with assays for MCA survival and soil enzyme activity....

  16. Analysis and design of controllers for a double inverted pendulum

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Poulsen, J K

    2003-01-01

    A physical control problem is studied with the μ methodology. The issues of modelling, uncertainty modelling, performance specification, controller design and laboratory implementation are discussed. The laboratory experiment is a double inverted pendulum placed on a cart. The limitations...

  17. Next Generation Nuclear Plant Resilient Control System Functional Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lynne M. Stevens

    2010-07-01

    Control Systems and their associated instrumentation must meet reliability, availability, maintainability, and resiliency criteria in order for high temperature gas-cooled reactors (HTGRs) to be economically competitive. Research, perhaps requiring several years, may be needed to develop control systems to support plant availability and resiliency. This report functionally analyzes the gaps between traditional and resilient control systems as applicable to HTGRs, which includes the Next Generation Nuclear Plant; defines resilient controls; assesses the current state of both traditional and resilient control systems; and documents the functional gaps existing between these two controls approaches as applicable to HTGRs. This report supports the development of an overall strategy for applying resilient controls to HTGRs by showing that control systems with adequate levels of resilience perform at higher levels, respond more quickly to disturbances, increase operational efficiency, and increase public protection.

  18. An asymptotic analysis of the so called intelligent PID controller

    OpenAIRE

    Praly, Laurent

    2010-01-01

    This note takes its origin from reading a paper by M. Fliess and C. Join, whose latest version is entitled Model-free control and intelligent PID controllers: towards a possible trivialization of nonlinear control? that can be obtained at http://arxiv.org/abs/0904.0322 Unfortunately in that paper, the authors write that . . . it is impossible of course to give a complete description of it and that the usual mathematical criteria for robust control become . . . irrelevant. In the following, to...

  19. Output controllability analysis of fixed speed wind turbine

    OpenAIRE

    Domínguez García, José Luís; García Planas, María Isabel

    2011-01-01

    This paper deals with the concepts of output controllability and steady output controllability, it demonstrates that they are not equivalent of concepts. A linear system has been calculated from the nonlinear equations of the squirrel cage induction generator, supposing it connected directly to the grid and assuming a steady state operating point. The study of output controllability and steady-output controllability concepts of the introduced system is done.

  20. Controllability and Operability Analysis of Heat Exchanger Networks Including Bypasses

    OpenAIRE

    Hernández, S; Balcazar-López, L.; Sánchez-Márquez, J. A.; González-García, G.

    2010-01-01

    In this paper, the influence of bypasses in heat exchanger networks on theoretical control properties and closed-loop behavior was investigated. According to theoretical control properties obtained using the singular value decomposition technique, the presence of bypasses increases flexibility of the heat exchanger network. This result was corroborated using closed-loop dynamic simulations using a proportional integral controller and a proportional integral controller with dynamic estimati...

  1. Resonance analysis in parallel voltage-controlled Distributed Generation inverters

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Blaabjerg, Frede; Chen, Zhe;

    2013-01-01

    Thanks to the fast responses of the inner voltage and current control loops, the dynamic behaviors of parallel voltage-controlled Distributed Generation (DG) inverters not only relies on the stability of load sharing among them, but subjects to the interactions between the voltage control loops of...

  2. Minor Component Analysis-based Landing Forecast System for Ship-borne Helicopter

    Institute of Scientific and Technical Information of China (English)

    ZHOU Bo,; SHI Ai-guo; WAN Lin; YANG Bao-zhang

    2005-01-01

    The general structure of ship-borne helicopter landing forecast system is presented, and a novel ship motion prediction model based on minor component analysis (MCA) is built up to improve the forecast effectiveness. To validate the feasibility of this landing forecast system, time series for the roll, pitch and heave are generated by simulation and then forecasted based on MCA. Simulation results show that ship-borne helicopters can land safely in higher sea condition while carrying on rescue or replenishment tasks at sea in terms of the landing forecast system.

  3. Synchronization analysis and control of three eccentric rotors in a vibrating system using adaptive sliding mode control algorithm

    Science.gov (United States)

    Kong, Xiangxi; Zhang, Xueliang; Chen, Xiaozhe; Wen, Bangchun; Wang, Bo

    2016-05-01

    In this paper, self- and controlled synchronizations of three eccentric rotors (ERs) in line driven by induction motors rotating in the same direction in a vibrating system are investigated. The vibrating system is a typical underactuated mechanical-electromagnetic coupling system. The analysis and control of the vibrating system convert to the synchronization motion problem of three ERs. Firstly, the self-synchronization motion of three ERs is analyzed according to self-synchronization theory. The criterions of synchronization and stability of self-synchronous state are obtained by using a modified average perturbation method. The significant synchronization motion of three ERs with zero phase differences cannot be implemented according to self-synchronization theory through analysis and simulations. To implement the synchronization motion of three ERs with zero phase differences, an adaptive sliding mode control (ASMC) algorithm based on a modified master-slave control strategy is employed to design the controllers. The stability of the controllers is verified by using Lyapunov theorem. The performances of the controlled synchronization system are presented by simulations to demonstrate the effectiveness of controllers. Finally, the effects of reference speed and non-zero phase differences on the controlled system are discussed to show the strong robustness of the proposed controllers. Additionally, the dynamic responses of the vibrating system in different synchronous states are analyzed.

  4. Performance Analysis of a DTC and SVM Based Field-Orientation Control Induction Motor Drive

    OpenAIRE

    Md. Rashedul Islam; Pintu Kumar Sadhu; Md. Maruful Islam; Md. Kamal Hossain

    2015-01-01

    This study presents a performance analysis of two most popular control strategies for Induction Motor (IM) drives: direct torque control (DTC) and space vector modulation (SVM) strategies. The performance analysis is done by applying field-orientation control (FOC) technique because of its good dynamic response. The theoretical principle, simulation results are discussed to study the dynamic performances of the drive system for individual control strategies using actual parameters of inductio...

  5. SYSTEMIC ANALYSIS OF CONTROL PROBLEMS OF SUGAR PRODUCTION IN LOGISTICAL SYSTEMS

    OpenAIRE

    Прокопенко, Тетяна Олександрівна; Ладанюк, Анатолій Петрович

    2012-01-01

    Strategic management, the latest technologies, project-oriented approach for sugar industry enterprises are of great interest nowadays. The general trend of modern control systems of sugar production is the creation of logistical systems. They provide information collection and processing, control of deviations of actual values of the company operation from the planned, production scheduling and control, stock planning and control, logistical analysis, calculation and analysis of produc...

  6. Control software analysis, Part I Open-loop properties

    CERN Document Server

    Feron, Eric

    2008-01-01

    As the digital world enters further into everyday life, questions are raised about the increasing challenges brought by the interaction of real-time software with physical devices. Many accidents and incidents encountered in areas as diverse as medical systems, transportation systems or weapon systems are ultimately attributed to "software failures". Since real-time software that interacts with physical systems might as well be called control software, the long litany of accidents due to real-time software failures might be taken as an equally long list of opportunities for control systems engineering. In this paper, we are interested only in run-time errors in those pieces of software that are a direct implementation of control system specifications: For well-defined and well-understood control architectures such as those present in standard textbooks on digital control systems, the current state of theoretical computer science is well-equipped enough to address and analyze control algorithms. It appears tha...

  7. Analysis of buffering process of control rod hydraulic absorber

    International Nuclear Information System (INIS)

    Control Rod Hydraulic Drive Mechanism(CRHDM) is a newly invented build-in control rod drive mechanism. Hydraulic absorber is the key part of this mechanism, and is used to cushion the control rod when the rod scrams. Thus, it prevents the control rod from being deformed and damaged. In this paper dynamics program ANSYS CFX is used to calculate all kinds of flow conditions in hydraulic absorber to obtain its hydraulic characteristics. Based on the flow resistance coefficients obtained from the simulation results, fluid mass and momentum equations were developed to get the trend of pressure change in the hydraulic cylinder and the displacement of the piston rod during the buffering process of the control rod. The results obtained in this paper indicate that the hydraulic absorber meets the design requirement. The work in this paper will be helpful for the design and optimization of the control rod hydraulic absorber. (author)

  8. Data management and analysis of HLS control system

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The control system of HLS (Hefei Light Source) is based on EPICS.The control data is held in a distributed database, which resides in several IOCs. An EPICS tool, AR, is used to archive the control data. A data management system is developed to manage the archived data. A number of CGI programs make it easy to access the data via WWW, and the programs also provide several functions for analyzing the data. The results can be displayed in various modes.

  9. Modeling Validation and Control Analysis for Controlled Temperature and Humidity of Air Conditioning System

    OpenAIRE

    Jing-Nang Lee; Tsung-Min Lin; Chien-Chih Chen

    2014-01-01

    This study constructs an energy based model of thermal system for controlled temperature and humidity air conditioning system, and introduces the influence of the mass flow rate, heater and humidifier for proposed control criteria to achieve the controlled temperature and humidity of air conditioning system. Then, the reliability of proposed thermal system model is established by both MATLAB dynamic simulation and the literature validation. Finally, the PID control strategy is applied for con...

  10. Design and Analysis of Controllers for an Double Inverted Pendulum

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Poulsen, Jesper Kildegaard

    2005-01-01

    A physical control problem is studied with the H_inf and the SSV methodology. The issues of modelling, uncertainty modelling, performance specification, controller design and laboratory implementation are discussed. The laboratory experiment is a double inverted pendulum placed on a cart. The lim......A physical control problem is studied with the H_inf and the SSV methodology. The issues of modelling, uncertainty modelling, performance specification, controller design and laboratory implementation are discussed. The laboratory experiment is a double inverted pendulum placed on a cart...

  11. Analysis of Controlled Trajectory Optimization for Canard Trajectory Correction Fuze

    Institute of Scientific and Technical Information of China (English)

    郭泽荣; 李世义; 申强

    2004-01-01

    The optimization method of the canard trajectory correction fuze's controlled trajectory phase is researched by using the aerodynamics of aerocraft and the optimal control theory, the trajectory parameters of the controlled trajectory phase based on the least energy cost are determined. On the basis of determining the control starting point and the target point, the optimal trajectory and the variation rule of the normal overload with the least energy cost are provided, when there is no time restriction in the simulation process. The results provide a theoretical basis for the structure design of the canard mechanism.

  12. Control of interferences in the analysis of low-concentration I 129

    International Nuclear Information System (INIS)

    Traces of uranium, cesium and tellurium interfere in the determination of I 129 by neutron activation analysis. The paper describes the procedures used to control or eliminate the interferences in the different steps of the analysis

  13. Stability Analysis and Controller Synthesis for Digital Single-Loop Voltage-Controlled Inverters

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Loh, Poh Chiang; Blaabjerg, Frede

    2016-01-01

    This paper analyzes first the stability of single-loop digital voltage control scheme for the LC-filtered voltage source inverters. It turns out that the phase lag, caused by the time delay of digital control system and by the use of integral controller, can stabilize the voltage loop without...

  14. Chemical analysis of substrates with controlled release fertilizer

    NARCIS (Netherlands)

    Kreij, de C.

    2004-01-01

    Water-soluble fertilizer added to media containing controlled release fertilizer cannot be analysed with the 1:1.5 volume water extract, because the latter increases the element content in the extract. During storage and stirring or mixing the substrate with the extractant, part of the controlled re

  15. Safety of timber: An analysis of quality control options

    NARCIS (Netherlands)

    Kovryga, A.; Stapel, P.; Van de Kuilen, J.W.G.

    2014-01-01

    The quality assurance of timber properties is important for the safety of timber structures. In the current study, the quality control options of timber are analysed under the prism of the different growth regions. Therefore, these options - machine and output control - are simulated in accordance w

  16. Analysis of Access Control Policies in Operating Systems

    Science.gov (United States)

    Chen, Hong

    2009-01-01

    Operating systems rely heavily on access control mechanisms to achieve security goals and defend against remote and local attacks. The complexities of modern access control mechanisms and the scale of policy configurations are often overwhelming to system administrators and software developers. Therefore, mis-configurations are common, and the…

  17. Case-control analysis of paternal age and trisomic anomalies

    NARCIS (Netherlands)

    De Souza, E.; Morris, Joan K.

    2010-01-01

    Objectives To determine whether older paternal age increases the risk of fathering a pregnancy with Patau (trisomy 13), Edwards (trisomy 18), Klinefelter (XXY) or XYY syndrome. Design Case-control: cases with each of these syndromes were matched to four controls with Down syndrome from within the sa

  18. Confirmatory Factor Analysis of the Work Locus of Control Scale

    Science.gov (United States)

    Oliver, Joseph E.; Jose, Paul E.; Brough, Paula

    2006-01-01

    Original formulations of the Work Locus of Control Scale (WLCS) proposed a unidimensional structure of this measure; however, more recently, evidence for a two-dimensional structure has been reported, with separate subscales for internal and external loci of control. The current study evaluates the one- and two-factor models with confirmatory…

  19. Application Analysis of Ad Lamp-box Controller

    Institute of Scientific and Technical Information of China (English)

    FANG Yuan; LU Bin

    2014-01-01

    The ad lamp-box controller is designed in consideration that ordinary urban ad lights usually remain lit through the night and a specially assigned staff needs to be on duty to control their switches. It can be automatically controlled with a photo resistance testing the day and night as well as a CD4060 chip controlling the length of time interval between switching the ad lamp-boxes on and off. In this way, both energy and labor can be saved with the controller. It is matching with the target of“constructing a conservation-minded society”in our country and deserves to be promoted in market with its practical signifi-cance.

  20. Material Control and Accounting Design Considerations for High-Temperature Gas Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Trond Bjornard; John Hockert

    2011-08-01

    The subject of this report is domestic safeguards and security by design (2SBD) for high-temperature gas reactors, focusing on material control and accountability (MC&A). The motivation for the report is to provide 2SBD support to the Next Generation Nuclear Plant (NGNP) project, which was launched by Congress in 2005. This introductory section will provide some background on the NGNP project and an overview of the 2SBD concept. The remaining chapters focus specifically on design aspects of the candidate high-temperature gas reactors (HTGRs) relevant to MC&A, Nuclear Regulatory Commission (NRC) requirements, and proposed MC&A approaches for the two major HTGR reactor types: pebble bed and prismatic. Of the prismatic type, two candidates are under consideration: (1) GA's GT-MHR (Gas Turbine-Modular Helium Reactor), and (2) the Modular High-Temperature Reactor (M-HTR), a derivative of Areva's Antares reactor. The future of the pebble-bed modular reactor (PBMR) for NGNP is uncertain, as the PBMR consortium partners (Westinghouse, PBMR [Pty] and The Shaw Group) were unable to agree on the path forward for NGNP during 2010. However, during the technology assessment of the conceptual design phase (Phase 1) of the NGNP project, AREVA provided design information and technology assessment of their pebble bed fueled plant design called the HTR-Module concept. AREVA does not intend to pursue this design for NGNP, preferring instead a modular reactor based on the prismatic Antares concept. Since MC&A relevant design information is available for both pebble concepts, the pebble-bed HTGRs considered in this report are: (1) Westinghouse PBMR; and (2) AREVA HTR-Module. The DOE Office of Nuclear Energy (DOE-NE) sponsors the Fuel Cycle Research and Development program (FCR&D), which contains an element specifically focused on the domestic (or state) aspects of SBD. This Material Protection, Control and Accountancy Technology (MPACT) program supports the present work

  1. Intensive glycemic control and macrovascular events in type 2 diabetes mellitus: a meta-analysis of randomized controlled trials

    Institute of Scientific and Technical Information of China (English)

    WU Hong; XU Mao-jin; ZOU Da-jin; HAN Qiao-jun; HU Xue

    2010-01-01

    Background There is no agreement as to whether intensive glucose control in type 2 diabetes can reduce the incidence of macrovascular events in these patients. We performed a meta-analysis comparing intensive glucose control or conventional glucose control in randomized controlled trials.Methods Databases including MEDLINE, EMBASE, and Cochrane controlled trials register, the Cochrane Library, and Science Citation Index were searched to find relevant trials. Outcome measures were the incidence of major macrovascular events.Results Six trials involving 28 065 patients were included. Analysis suggested that there was an obviously decreased incidence of major macrovascular events in patients having intensive glucose treatment vs. Controls (RR 0.92; 95% Cl 0.87, 0.98; P=0.005). However, intensive glycemia control strategies in type 2 diabetes showed no significant impact on the incidence of death from any cause compared with conventional glycemia control strategies, intensive 14.7%, controls 12.0% (RR 0.95; 95% Cl 0.80, 1.12; P=0.55), as well as on the incidence of cardiovascular death, intensive 3.7%,controls 3.6% (RR 1.10, 95% Cl 0.79, 1.53; P=0.57).Conclusions Control of glycemia to normal (or near normal levels) in type 2 diabetes appears to be effective in reducing the incidence of major macrovascular events, but there were no significant differences of either the mortality from any cause or from cardiovascular death between the two glycemia-control strategies.

  2. Variation Analysis and Stability Control for Measurement Process

    Institute of Scientific and Technical Information of China (English)

    ZHAO Feng-yu; MA Yi-zhong; Bo Bergman; XU Ji-chao

    2002-01-01

    Based on a two-section measuring method, a data collection sheet is formed. According to the data collected, the variation sources of a measurement process are analyzed and general guidelines for variation diagnosis are suggested. In our previous study, a method is presented to control the deviation of measurement system, but it is not sensitive to mean value variation and mean value drift. In this paper, a simplified data collection scheme via two-section measuring method is introduced to control both variation and center drift of measurement process. Based on this scheme, traditional SPC charts for variation control and EWMA chart for mean value drift are given.

  3. Analysis of Decentralized Control for Absorption Cycle Heat Pumps

    DEFF Research Database (Denmark)

    Vinther, Kasper; Just Nielsen, Rene; Nielsen, Kirsten Mølgaard;

    2015-01-01

    Email Print Request Permissions This paper investigates decentralized control structures for absorption cycle heat pumps and a dynamic nonlinear model of a single-effect LiBr-water absorption system is used as case study. The model has four controllable inputs, which can be used to stabilize the ...... to minimize the effect of cross couplings and improve stability with the right pairing of input and output. Simulation of selected candidate input-output pairings demonstrate that decentralized control can provide stable operation of the heat pump....

  4. Automatic analysis of signals during Eddy currents controls

    International Nuclear Information System (INIS)

    A method and the corresponding instrument have been developed for automatic analysis of Eddy currents testing signals. This apparatus enables at the same time the analysis, every 2 milliseconds, of two signals at two different frequencies. It can be used either on line with an Eddy Current testing instrument or with a magnetic tape recorder

  5. On Static and Dynamic Control-Flow Information in Program Analysis and Transformation

    DEFF Research Database (Denmark)

    Damian, Daniel

    This thesis addresses several aspects of static and dynamic control-flow information in programming languages, by investigating its interaction with program transformation and program analysis. Control-flow information indicates for each point in a program the possible program points to be executed...... of the program may be executed next. A control-flow analysis approximates the dynamic control-flow information with conservative static control-flow information. We explore the impact of a continuation-passing-style (CPS) transformation on the result of a constraint-based control-flow analysis over Moggi...... next. Control-flow information in a program may be static, as when the syntax of the program directly determines which parts of the program may be executed next. Control-flow information may be dynamic, as when run-time values and inputs of the program are required to determine which parts...

  6. Modeling validation and control analysis for controlled temperature and humidity of air conditioning system.

    Science.gov (United States)

    Lee, Jing-Nang; Lin, Tsung-Min; Chen, Chien-Chih

    2014-01-01

    This study constructs an energy based model of thermal system for controlled temperature and humidity air conditioning system, and introduces the influence of the mass flow rate, heater and humidifier for proposed control criteria to achieve the controlled temperature and humidity of air conditioning system. Then, the reliability of proposed thermal system model is established by both MATLAB dynamic simulation and the literature validation. Finally, the PID control strategy is applied for controlling the air mass flow rate, humidifying capacity, and heating, capacity. The simulation results show that the temperature and humidity are stable at 541 sec, the disturbance of temperature is only 0.14 °C, 0006 kg(w)/kg(da) in steady-state error of humidity ratio, and the error rate is only 7.5%. The results prove that the proposed system is an effective controlled temperature and humidity of an air conditioning system.

  7. Analysis of Information Quality in event triggered Smart Grid Control

    DEFF Research Database (Denmark)

    Kristensen, Thomas le Fevre; Olsen, Rasmus Løvenstein; Rasmussen, Jakob Gulddahl

    2015-01-01

    The integration of renewable energy sources into the power grid requires added control intelligence which imposes new communication requirements onto the future power grid. Since large scale implementation of new communication infrastructure is infeasible, we consider methods of increasing...

  8. Discomfort Analysis in Computerized Numeric Control Machine Operations

    OpenAIRE

    Muthukumar, Krishnamoorthy; Sankaranarayanasamy, Krishnasamy; Ganguli, Anindya Kumar

    2012-01-01

    Objectives The introduction of computerized numeric control (CNC) technology in manufacturing industries has revolutionized the production process, but there are some health and safety problems associated with these machines. The present study aimed to investigate the extent of postural discomfort in CNC machine operators, and the relationship of this discomfort to the display and control panel height, with a view to validate the anthropometric recommendation for the location of the display a...

  9. Modeling,Control Design and Performance Analysis of PHEV Powertrain

    Institute of Scientific and Technical Information of China (English)

    Zhang Xin(张欣); Wang Daxing

    2004-01-01

    Developing Parallel Hybrid Electric Vehicle (PHEV) is becoming an active research field of new type electric automobiles for its high fuel economy and low emissions. Due to the complexity of PHEV powertrain, simulation becomes an important method in study of PHEV control strategy. In this paper, a forward-facing simulation software and the models of PHEV powertrain based on MATLAB/Simulink are developed to study on the PHEV control strategy. The simulation results are also shown in the paper.

  10. Optimal discrimination of multiple quantum systems: controllability analysis

    Energy Technology Data Exchange (ETDEWEB)

    Turinici, Gabriel [INRIA Rocquencourt, BP 105, 78153 Le Chesnay Cedex (France); Ramakhrishna, Viswanath [Department of Mathematical Sciences and Center for Signals, Systems and Communications, University of Texas at Dallas, PO Box 830688, Richardson, TX 75083 (United States); Li Baiqing [Department of Chemistry, Princeton University, Princeton, NJ 08544 (United States); Rabitz, Herschel [Department of Chemistry, Princeton University, Princeton, NJ 08544 (United States)

    2004-01-09

    A theoretical study is presented concerning the ability to dynamically discriminate between members of a set of different (but possibly similar) quantum systems. This discrimination is analysed in terms of independently and simultaneously steering about the wavefunction of each component system to a target state of interest using a tailored control (i.e. laser) field. Controllability criteria are revealed and their applicability is demonstrated in simple cases. Discussion is also presented in some uncontrollable cases.

  11. Optimal discrimination of multiple quantum systems: controllability analysis

    Science.gov (United States)

    Turinici, Gabriel; Ramakhrishna, Viswanath; Li, Baiqing; Rabitz, Herschel

    2004-01-01

    A theoretical study is presented concerning the ability to dynamically discriminate between members of a set of different (but possibly similar) quantum systems. This discrimination is analysed in terms of independently and simultaneously steering about the wavefunction of each component system to a target state of interest using a tailored control (i.e. laser) field. Controllability criteria are revealed and their applicability is demonstrated in simple cases. Discussion is also presented in some uncontrollable cases.

  12. On-line Texture Analysis for Magnetic Property Control

    OpenAIRE

    Bunge, H. J.; Kopineck, H. J.; Wagner, F

    1989-01-01

    Magnetic properties of hard and soft magnetic materials are strongly anisotropic, i.e. they depend on the crystal direction in which they are being considered. Technological materials are usually polycrystalline. Hence, their properties are orientation mean values of the properties of the crystallites with the texture of the material as the weight function. Inspection and control of magnetic properties of materials thus requires inspection and control of the materials texture which can be car...

  13. A Goal-Function Approach to Analysis of Control Situations

    DEFF Research Database (Denmark)

    Lind, Morten

    2010-01-01

    The concept of situations plays a central role in all theories of meaning and context. and serve to frame or group events and other occurrences into coherent meaningful wholes. Situations are typed, may be interconnected and organized into higher level structures. In operation of industrial...... to systems modeling like Multilevel Flow Modeling can be used to represent control situations. The paper will describe an action theoretical foundation for MFM and its use for the development of a theory of control situations....

  14. Analysis on electronic control unit of continuously variable transmission

    Science.gov (United States)

    Cao, Shuanggui

    Continuously variable transmission system can ensure that the engine work along the line of best fuel economy, improve fuel economy, save fuel and reduce harmful gas emissions. At the same time, continuously variable transmission allows the vehicle speed is more smooth and improves the ride comfort. Although the CVT technology has made great development, but there are many shortcomings in the CVT. The CVT system of ordinary vehicles now is still low efficiency, poor starting performance, low transmission power, and is not ideal controlling, high cost and other issues. Therefore, many scholars began to study some new type of continuously variable transmission. The transmission system with electronic systems control can achieve automatic control of power transmission, give full play to the characteristics of the engine to achieve optimal control of powertrain, so the vehicle is always traveling around the best condition. Electronic control unit is composed of the core processor, input and output circuit module and other auxiliary circuit module. Input module collects and process many signals sent by sensor and , such as throttle angle, brake signals, engine speed signal, speed signal of input and output shaft of transmission, manual shift signals, mode selection signals, gear position signal and the speed ratio signal, so as to provide its corresponding processing for the controller core.

  15. Acupuncture-Point Stimulation for Postoperative Pain Control: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    OpenAIRE

    Xian-Liang Liu; Jing-Yu Tan; Alex Molassiotis; Suen, Lorna K P; Yan Shi

    2015-01-01

    The purpose of this study was to evaluate the effectiveness of Acupuncture-point stimulation (APS) in postoperative pain control compared with sham/placebo acupuncture or standard treatments (usual care or no treatment). Only randomized controlled trials (RCTs) were included. Meta-analysis results indicated that APS interventions improved VAS scores significantly and also reduced total morphine consumption. No serious APS-related adverse effects (AEs) were reported. There is Level I evidence ...

  16. A stability analysis method for the fuzzy controller and its application

    International Nuclear Information System (INIS)

    A method is proposed to analyze the stability of a fuzzy controller and the method is applied to a fuzzy controller developed in this work to automatically control the steam generator water level in the pressurized water reactor (PWR). The stability analysis method is devised from the relationships between the fuzzy controller and the conventional PI (Proportional and Integral) controller. The relationships are derived from the theoretical analysis and modeling of the widely used fuzzy controller having two inputs (Error, Rate) and one output with triangular type membership functions. In addition, an analyzable 9-Rule fuzzy controller is designed and computer-simulated for the automatic control of the steam generator water level in the PWR to employ the developed stability analysis method. This study shows that the stability analysis method based on the comparison of the equivalent PI gain ranges of the fuzzy controller with that of a linear PI controller provides very meaningful ideas for the design of stable fuzzy controller through the computer simulations. Therefore, the method suggested in this work can be used in a confirmatory process to check the stability of a fuzzy controller designed with two inputs (error, rate) and also the method would be used as an useful guidance to efficiently design and tune the fuzzy controller

  17. Luminescent properties and energy transfer process of Sm3+-Eu3+ co-doped MY2(MoO4)4 (M=Ca, Sr and Ba) red-emitting phosphors

    Science.gov (United States)

    Ye, Menglin; Zhou, Gaojian; Zhou, Liqun; Lu, Di; Li, Yue; Xiong, Xing; Yang, Kunzhou; Chen, Menghuan; Pan, Yaxi; Wu, Peng; Wang, Zheng; Liu, Hongying; Xia, Qinghua

    2016-09-01

    MY2(MoO4)4:Sm3+ and MY2(MoO4)4:xSm3+,yEu3+ (M=Ca, Sr and Ba) phosphors were successfully prepared using solid-state reaction route, and their luminescent properties and energy transfer process from Sm3+ to Eu3+ were systematically investigated. The results indicate that MY2(MoO4)4:Sm3+ phosphors can be effectively excited by 407 nm near UV light originating from the 6H5/2 → 4F7/2 transition of Sm3+, and exhibit a satisfactory red emission at 646 nm attributed to the 4G5/2 → 6H9/2 transition of Sm3+, in which the emission intensity of SrY2(MoO4)4:Sm3+ is the strongest among the MY2(MoO4)4:Sm3+ (M=Ca, Sr and Ba) phosphors. For Eu3+ co-doped MY2(MoO4)4:Sm3+ samples, with increasing Eu3+ doping content, the main emission peaks of Sm3+ (approximately 646 nm) are decreased, but the emission peaks and intensity of Eu3+ are increased while the maximum intensity of luminescence at the Eu3+ concentration 0.9. The introduction of Eu3+ in the MY2(MoO4)4:Sm3+ phosphors can remarkably generate a strong emission line at 616 nm, originating from the 5D0→7F2 transition of Eu3+ and Sm3+ (4G5/2) → Eu3+ (5D0) effective energy transfer process. The energy transfer mechanism from Sm3+ to Eu3+ was discussed in detail.

  18. Economic Analysis of Solid-Set Sprinklers to Control Dust in Feedlots

    OpenAIRE

    Amosson, Stephen H.; Guerrero, Bridget L.; Almas, Lal K.

    2006-01-01

    Feedlot dust is a critical problem that contributes to cattle death and illness, as well as, air pollution. This analysis identifies the effects of feedlot dust on cattle and the benefits/methods of controlling feedlot dust. A cost analysis of one popular method of controlling dust, solid-set sprinklers is presented.

  19. Performance Analysis of Phase Controlled Unidirectional and Bidirectional AC Voltage Controllers

    Directory of Open Access Journals (Sweden)

    Abdul Sattar Larik

    2011-01-01

    Full Text Available AC voltage controllers are used to vary the output ac voltage from a fixed ac input source. They are also commonly called ac voltage regulators or ac choppers. The output voltage is either controlled by PAC (Phase Angle Control method or on-off control method. Due to various advantages of ac voltage controllers, such as high efficiency, simplicity, low cost and ability to control large amount of power they efficiently control the speed of ac motors, light dimming and industrial heating, etc. These converters are variable structure systems and generate harmonics during the operation which will affect the power quality when connected to system network. During the last couple of years, a number of new semiconductor devices and various power electronic converters has been introduced. Accordingly the subject of harmonics and its problems are of great concern to power industry and customers. In this research work, initially the simulation models of single phase unidirectional and bidirectional ac voltage controllers were developed by using MATLAB software. The harmonics of these models are investigated by simulation. In the end, the harmonics were also analyzed experimentally. The simulated as well as experimental results are presented.

  20. Analysis of Control Strategies for Aircraft Flight Upset Recovery

    Science.gov (United States)

    Crespo, Luis G.; Kenny, Sean P.; Cox, David E.; Muri, Daniel G.

    2012-01-01

    This paper proposes a framework for studying the ability of a control strategy, consisting of a control law and a command law, to recover an aircraft from ight conditions that may extend beyond the normal ight envelope. This study was carried out (i) by evaluating time responses of particular ight upsets, (ii) by evaluating local stability over an equilibrium manifold that included stall, and (iii) by bounding the set in the state space from where the vehicle can be safely own to wings-level ight. These states comprise what will be called the safely recoverable ight envelope (SRFE), which is a set containing the aircraft states from where a control strategy can safely stabilize the aircraft. By safe recovery it is implied that the tran- sient response stays between prescribed limits before converging to a steady horizontal ight. The calculation of the SRFE bounds yields the worst-case initial state corresponding to each control strategy. This information is used to compare alternative recovery strategies, determine their strengths and limitations, and identify the most e ective strategy. In regard to the control law, the authors developed feedback feedforward laws based on the gain scheduling of multivariable controllers. In regard to the command law, which is the mechanism governing the exogenous signals driving the feed- forward component of the controller, we developed laws with a feedback structure that combines local stability and transient response considera- tions. The upset recovery of the Generic Transport Model, a sub-scale twin-engine jet vehicle developed by NASA Langley Research Center, is used as a case study.

  1. Controllability analysis of transcriptional regulatory networks reveals circular control patterns among transcription factors

    DEFF Research Database (Denmark)

    Österlund, Tobias; Bordel, Sergio; Nielsen, Jens

    2015-01-01

    Transcriptional regulation is the most committed type of regulation in living cells where transcription factors (TFs) control the expression of their target genes and TF expression is controlled by other TFs forming complex transcriptional regulatory networks that can be highly interconnected. Here...... we analyze the topology and organization of nine transcriptional regulatory networks for E. coli, yeast, mouse and human, and we evaluate how the structure of these networks influences two of their key properties, namely controllability and stability. We calculate the controllability for each network...... as a measure of the organization and interconnectivity of the network. We find that the number of driver nodes n(D) needed to control the whole network is 64% of the TFs in the E. coli transcriptional regulatory network in contrast to only 17% for the yeast network, 4% for the mouse network and 8...

  2. Stability analysis and μ-synthesis control of brake systems

    OpenAIRE

    Lignon, Sylvain; Sinou, Jean-Jacques; Jezequel, Louis

    2006-01-01

    The concept of friction-induced brake vibrations, commonly known as judder, is investigated. Judder vibration is based on the class of geometrically induced or kinematic constraint instability. After presenting the modal coupling mechanism and the associated dynamic model, a stability analysis as well as a sensitivity analysis have been conducted in order to identify physical parameters for a brake design avoiding friction-induced judder instability. Next, in order to reduce the size of the i...

  3. Stability analysis and \\mu-synthesis control of brake systems

    OpenAIRE

    Lignon, Sylvain; Sinou, Jean-Jacques; Jezequel, Louis

    2008-01-01

    The concept of friction-induced brake vibrations, commonly known as judder, is investigated. Judder vibration is based on the class of geometrically induced or kinematic constraint instability. After presenting the modal coupling mechanism and the associated dynamic model, a stability analysis as well as a sensitivity analysis have been conducted in order to identify physical parameters for a brake design avoiding friction-induced judder instability. Next, in order to reduce the size of the i...

  4. Spatial analysis of childhood cancer: a case/control study.

    Directory of Open Access Journals (Sweden)

    Rebeca Ramis

    Full Text Available Childhood cancer was the leading cause of death among children aged 1-14 years for 2012 in Spain. Leukemia has the highest incidence, followed by tumors of the central nervous system (CNS and lymphomas (Hodgkin lymphoma, HL, and Non-Hodgkin's lymphoma, NHL. Spatial distribution of childhood cancer cases has been under concern with the aim of identifying potential risk factors.The two objectives are to study overall spatial clustering and cluster detection of cases of the three main childhood cancer causes, looking to increase etiological knowledge.We ran a case-control study. The cases were children aged 0 to 14 diagnosed with leukemia, lymphomas (HL and NHL or CNS neoplasm in five Spanish regions for the period 1996-2011. As a control group, we used a sample from the Birth Registry matching every case by year of birth, autonomous region of residence and sex with six controls. We geocoded and validated the address of the cases and controls. For our two objectives we used two different methodologies. For the first, for overall spatial clustering detection, we used the differences of K functions from the spatial point patterns perspective proposed by Diggle and Chetwynd and the second, for cluster detection, we used the spatial scan statistic proposed by Kulldorff with a level for statistical significance of 0.05.We had 1062 cases of leukemia, 714 cases of CNS, 92 of HL and 246 of NHL. Accordingly we had 6 times the number of controls, 6372 controls for leukemia, 4284 controls for CNS, 552 controls for HL and 1476 controls for NHL. We found variations in the estimated empirical D(s for the different regions and cancers, including some overall spatial clustering for specific regions and distances. We did not find statistically significant clusters.The variations in the estimated empirical D(s for the different regions and cancers could be partially explained by the differences in the spatial distribution of the population; however, according to the

  5. Stability analysis of traffic flow with extended CACC control models

    Science.gov (United States)

    Ya-Zhou, Zheng; Rong-Jun, Cheng; Siu-Ming, Lo; Hong-Xia, Ge

    2016-06-01

    To further investigate car-following behaviors in the cooperative adaptive cruise control (CACC) strategy, a comprehensive control system which can handle three traffic conditions to guarantee driving efficiency and safety is designed by using three CACC models. In this control system, some vital comprehensive information, such as multiple preceding cars’ speed differences and headway, variable safety distance (VSD) and time-delay effect on the traffic current and the jamming transition have been investigated via analytical or numerical methods. Local and string stability criterion for the velocity control (VC) model and gap control (GC) model are derived via linear stability theory. Numerical simulations are conducted to study the performance of the simulated traffic flow. The simulation results show that the VC model and GC model can improve driving efficiency and suppress traffic congestion. Project supported by the National Natural Science Foundation of China (Grant Nos. 71571107 and 11302110). The Scientific Research Fund of Zhejiang Province, China (Grant Nos. LY15A020007, LY15E080013, and LY16G010003). The Natural Science Foundation of Ningbo City (Grant Nos. 2014A610030 and 2015A610299), the Fund from the Government of the Hong Kong Administrative Region, China (Grant No. CityU11209614), and the K C Wong Magna Fund in Ningbo University, China.

  6. Performance analysis of sequential tests in process control

    Energy Technology Data Exchange (ETDEWEB)

    Hoyer, K.K. [Northwestern Univ., Evanston, IL (United States). Dept. of Industrial Engineering/Management Science

    1994-04-01

    In recent years, a great deal of emphasis has been placed on quality control of industrial processes. In particular, numerous statistical techniques exist which are designed to continually check an industrial process for machine or component failure, thereby determining if the process is under control, or if it is becoming out of control. In this study, the authors consider a very powerful class of quality control techniques known as sequential tests. Sequential tests classify a set of observations in a manner similar to statistical hypothesis tests, but are characterized by a random sample size. Perhaps the best known sequential test is Wald`s sequential probability ratio test. The sequential probability ratio test (SPRT) is a log likelihood ratio based test for simple or composite hypotheses. After taking each observation, the SPRT decides whether to accept the null hypothesis, reject the null hypothesis, or continue sampling. For the purpose of quality control, an SPRT can be conducted repeatedly over time as incoming observations are received. In the following section, the authors reviews the sequential probability ratio test and state some of its properties. In Section 3, they formulate a Markov additive model which allows them to study the sequential probability ratio test under various types of process behavior. Section 4 develops the theoretical results and the methodological approach that allows them to bound the first passage time distributions of their model. Section 5 illustrates their techniques through numerical examples.

  7. Nonlinear Analysis and Intelligent Control of Integrated Vehicle Dynamics

    Directory of Open Access Journals (Sweden)

    C. Huang

    2014-01-01

    Full Text Available With increasing and more stringent requirements for advanced vehicle integration, including vehicle dynamics and control, traditional control and optimization strategies may not qualify for many applications. This is because, among other factors, they do not consider the nonlinear characteristics of practical systems. Moreover, the vehicle wheel model has some inadequacies regarding the sideslip angle, road adhesion coefficient, vertical load, and velocity. In this paper, an adaptive neural wheel network is introduced, and the interaction between the lateral and vertical dynamics of the vehicle is analyzed. By means of nonlinear analyses such as the use of a bifurcation diagram and the Lyapunov exponent, the vehicle is shown to exhibit complicated motions with increasing forward speed. Furthermore, electric power steering (EPS and active suspension system (ASS, which are based on intelligent control, are used to reduce the nonlinear effect, and a negotiation algorithm is designed to manage the interdependences and conflicts among handling stability, driving smoothness, and safety. Further, a rapid control prototype was built using the hardware-in-the-loop simulation platform dSPACE and used to conduct a real vehicle test. The results of the test were consistent with those of the simulation, thereby validating the proposed control.

  8. Motion and vibration control of a slewing flexible structure by SMA actuators and parameter sensitivity analysis

    Science.gov (United States)

    Janzen, F. C.; Tusset, A. M.; Piccirillo, V.; Balthazar, J. M.; Brasil, R. M. L. R. F.

    2015-11-01

    This work presents two approaches to the problem of vibration and positioning control of a flexible structural beam driven by a DC motor. The position is controlled by the current applied to the DC motor armature. A Shape Memory Alloy (SMA) actuator controls vibrations of the flexible structural beam. The State Dependent Riccati Equation (SDRE) technique is used to provide a control action which uses sub-optimal control and system local stability search. The robustness of these two controllers is tested by sensitivity analysis to parametric uncertainties. Numerical simulations results are presented to demonstrate the effectiveness of the proposed control strategy.

  9. Detecting altered connectivity patterns in HIV associated neurocognitive impairment using mutual connectivity analysis

    Science.gov (United States)

    Abidin, Anas Zainul; D'Souza, Adora M.; Nagarajan, Mahesh B.; Wismüller, Axel

    2016-03-01

    The use of functional Magnetic Resonance Imaging (fMRI) has provided interesting insights into our understanding of the brain. In clinical setups these scans have been used to detect and study changes in the brain network properties in various neurological disorders. A large percentage of subjects infected with HIV present cognitive deficits, which are known as HIV associated neurocognitive disorder (HAND). In this study we propose to use our novel technique named Mutual Connectivity Analysis (MCA) to detect differences in brain networks in subjects with and without HIV infection. Resting state functional MRI scans acquired from 10 subjects (5 HIV+ and 5 HIV-) were subject to standard preprocessing routines. Subsequently, the average time-series for each brain region of the Automated Anatomic Labeling (AAL) atlas are extracted and used with the MCA framework to obtain a graph characterizing the interactions between them. The network graphs obtained for different subjects are then compared using Network-Based Statistics (NBS), which is an approach to detect differences between graphs edges while controlling for the family-wise error rate when mass univariate testing is performed. Applying this approach on the graphs obtained yields a single network encompassing 42 nodes and 65 edges, which is significantly different between the two subject groups. Specifically connections to the regions in and around the basal ganglia are significantly decreased. Also some nodes corresponding to the posterior cingulate cortex are affected. These results are inline with our current understanding of pathophysiological mechanisms of HIV associated neurocognitive disease (HAND) and other HIV based fMRI connectivity studies. Hence, we illustrate the applicability of our novel approach with network-based statistics in a clinical case-control study to detect differences connectivity patterns.

  10. Analysis and control of nitriding and nitrocarburizing atmospheres

    Energy Technology Data Exchange (ETDEWEB)

    Sproge, L. [AGA AB Lidingo (Sweden); Midea, S.J. [AGA Gas, Inc., Cleveland, OH (United States)

    1995-12-31

    This paper is a summary of research on control parameters and the factors which influence formation of compound layers in the nitriding and ferritic nitrocarburizing processes. The major gas-exchange reactions, mass-transfer mechanisms, and their kinetics are discussed for both these processes. Carbon, nitrogen and oxygen activities are calculated as a function of atmosphere gas composition. These activities are compared to experimental values and the obtained microstructures are analyzed. Development of a control scheme for these processes has been hindered both by a fundamental understanding of the atmosphere kinetics and a reliable means of monitoring the atmosphere. However, today there are possibilities to control such an atmosphere by means of an oxygen probe, utilizing software to calculate the atmosphere activities based upon the incoming gas mixture, temperature, and probe millivolt signal.

  11. Global sensitivity analysis in control-augmented structural synthesis

    Science.gov (United States)

    Bloebaum, Christina L.

    1989-01-01

    In this paper, an integrated approach to structural/control design is proposed in which variables in both the passive (structural) and active (control) disciplines of an optimization process are changed simultaneously. The global sensitivity equation (GSE) method of Sobieszczanski-Sobieski (1988) is used to obtain the behavior sensitivity derivatives necessary for the linear approximations used in the parallel multidisciplinary synthesis problem. The GSE allows for the decoupling of large systems into smaller subsystems and thus makes it possible to determine the local sensitivities of each subsystem's outputs to its inputs and parameters. The advantages in using the GSE method are demonstrated using a finite-element representation of a truss structure equipped with active lateral displacement controllers, which is undergoing forced vibration.

  12. Planning and control of maintenance systems modelling and analysis

    CERN Document Server

    Duffuaa, Salih O

    2015-01-01

    Analyzing maintenance as an integrated system with objectives, strategies and processes that need to be planned, designed, engineered, and controlled using statistical and optimization techniques, the theme of this book is the strategic holistic system approach for maintenance. This approach enables maintenance decision makers to view maintenance as a provider of a competitive edge not a necessary evil. Encompassing maintenance systems; maintenance strategic and capacity planning, planned and preventive maintenance, work measurements and standards, material (spares) control, maintenance operations and control, planning and scheduling, maintenance quality, training, and others, this book gives readers an understanding of the relevant methodology and how to apply it to real-world problems in industry. Each chapter includes a number exercises and is suitable as a textbook or a reference for a professionals and practitioners whilst being of interest to industrial engineering, mechanical engineering, electrical en...

  13. Design and analysis of a rotary motion controller

    Directory of Open Access Journals (Sweden)

    Julio Cesar Caye

    2015-12-01

    Full Text Available This paper presents the design of a rotary motion controller based on the peritrochoid geometry of the rotary (Wankle engine. It uses an orifice limited flow of incompressible fluid between the chambers of the Wankle-type geometry to control the rotation of the rotor. The paper develops the theory of operation and then implements the design as a Matlab model to simulate the motion control under various conditions. It is found that the time to reach stabilised motion is determined by the orifice size and fluid density. When stabilised motion is achieved, the motion dependence on material and geometry factors is determined by the orifice flow equation. The angular velocity is also found to have a square root dependence on the applied torque when in the stabilised regime.

  14. Fracture analysis for controlled blasting demolition of reinforced concrete structures

    International Nuclear Information System (INIS)

    Toward establishing a design method for controlled blasting demolition used for the designed dismantling of large reinforced concrete (RC) structures, this study is intended to prove the overall suitability and efficiency of this method. The previous paper (Controlled Blasting for Demolition of Biological Shield Concrete Wall: Part 2) described an application of controlled blasting demolition to an inner part of the radioactive RC biological shield in the JPDR (Japan Power Demonstration Reactor). Through this experience, it was confirmed that the partial demolition of the structure was carried out safely and rationally using this method. In order to clarify the characteristics of blasting effect, an RC cylinder blasting test was performed and the results of this test were compared with analytical simulation of this test using the discrete element method (DEM) and the finite element method (FEM). This paper outlines the test, the analyses and the comparison. (author)

  15. Structure analysis of a class of fuzzy controllers using pseudo trapezoid shaped membership functions

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    An output expression of a class of dual-input single-output fuzzy controllers using pseudo trapezoid shaped membership function is given. By structure analysis it is proved that this class of fuzzy controllers is the sum of a global two-dimensional multi-level relay and a local linear or nonlinear proportional-integral or proportional-differential controller. And the output of this class of fuzzy controllers is a continuous, non-decreasing function of its input variables. These and other meaningful results derived from structure analysis based on the output expressions can guide the design of fuzzy controllers.

  16. Structure analysis of a class of fuzzy controllers using pseudo trapezoid shaped membership functions

    Institute of Scientific and Technical Information of China (English)

    曾珂; 张乃尧; 徐文立

    2000-01-01

    An output expression of a class of dual-input single-output fuzzy controllers using pseudo trapezoid shaped membership function is given. By structure analysis it is prdved that this class of fuzzy controllers is the sum of a global two-dimensional multi-level relay and a local linear or nonlinear proportional-integral or proportional-differential controller. And the output of this class of fuzzy controllers is a continuous, non-decreasing function of its input variables. These and other meaningful results derived from structure analysis based on the output expressions can guide the design of fuzzy controllers.

  17. Analysis of achievable disturbance attenuation in a precision magnetically-suspended motion control system

    Science.gov (United States)

    Kuzin, Alexander V.; Holmes, Michael L.; Behrouzjou, Roxana; Trumper, David L.

    1994-01-01

    The results of the analysis of the achievable disturbance attenuation to get an Angstrom motion control resolution and macroscopic travel in a precision magnetically-suspended motion control system are presented in this paper. Noise sources in the transducers, electronics, and mechanical vibrations are used to develop the control design.

  18. Analysis of unconstrained nonlinear MPC schemes with time varying control horizon

    CERN Document Server

    Grüne, Lars; Seehafer, Martin; Worthmann, Karl

    2010-01-01

    For discrete time nonlinear systems satisfying an exponential or finite time controllability assumption, we present an analytical formula for a suboptimality estimate for model predictive control schemes without stabilizing terminal constraints. Based on our formula, we perform a detailed analysis of the impact of the optimization horizon and the possibly time varying control horizon on stability and performance of the closed loop.

  19. Ego Depletion and the Strength Model of Self-Control: A Meta-Analysis

    Science.gov (United States)

    Hagger, Martin S.; Wood, Chantelle; Stiff, Chris; Chatzisarantis, Nikos L. D.

    2010-01-01

    According to the strength model, self-control is a finite resource that determines capacity for effortful control over dominant responses and, once expended, leads to impaired self-control task performance, known as "ego depletion". A meta-analysis of 83 studies tested the effect of ego depletion on task performance and related outcomes,…

  20. Design and analysis of control charts for standard deviation with estimated parameters

    NARCIS (Netherlands)

    M. Schoonhoven; M. Riaz; R.J.M.M. Does

    2011-01-01

    This paper concerns the design and analysis of the standard deviation control chart with estimated limits. We consider an extensive range of statistics to estimate the in-control standard deviation (Phase I) and design the control chart for real-time process monitoring (Phase II) by determining the

  1. A strategic analysis of future growth options for an established process control company

    OpenAIRE

    Levesque, Sheila Lynne

    2007-01-01

    This project speaks to the prevailing business environment presently encountered at WESTCOAST Controls Ltd (WESTCOAST), a leading process control company in British Columbia, Canada. The scope of the project covers topics such as company overview, external industry analysis, and internal company analysis including strategic tools such as Porter's 5 Forces. The project concludes with a recommendation for the restructuring of the control systems & solutions division for improved performan...

  2. Qualitative analysis and control of complex neural networks with delays

    CERN Document Server

    Wang, Zhanshan; Zheng, Chengde

    2016-01-01

    This book focuses on the stability of the dynamical neural system, synchronization of the coupling neural system and their applications in automation control and electrical engineering. The redefined concept of stability, synchronization and consensus are adopted to provide a better explanation of the complex neural network. Researchers in the fields of dynamical systems, computer science, electrical engineering and mathematics will benefit from the discussions on complex systems. The book will also help readers to better understand the theory behind the control technique and its design.

  3. A Preliminary Analysis of California's New Local Control Funding Formula

    Science.gov (United States)

    Wolf, Rebecca; Sands, Janelle

    2016-01-01

    California recently overhauled its K-12 public education finance system. Enacted in 2013, the Local Control Funding Formula (LCFF) replaced California's 40-year-old funding formula. The LCFF increases district officials' fiscal flexibility; provides more resources to districts serving larger proportions of low-income, English learner (EL), and…

  4. Qantitative Analysis and Design of a Rudder Roll Damping Controller

    DEFF Research Database (Denmark)

    Hearns, G.; Blanke, M.

    A rudder roll damping controller is designed using Quantitative Feedback Theory to be robust for changes in the ships metacentric height. The analytical constraint due to the non-minimum phase behaviour of the rudder to roll is analysed using the Poisson Integral Formula and it is shown how...

  5. Quantitative Analysis and Design of a Rudder Roll Damping Controller

    DEFF Research Database (Denmark)

    Hearns, G.; Blanke, M.

    1998-01-01

    A rudder roll damping controller is designed using Quantitative feedback theory to be robust for changes in the ships metacentric height. The analytical constraint due to the non-minimum phase behaviour of the rudder to roll is analysed using the Poisson Integral Formula and it is shown how...

  6. Analysis of translation initiation using a translation control reporter system

    NARCIS (Netherlands)

    Wiesenthal, Volker; Leutz, Achim; Calkhoven, Cornelis F

    2006-01-01

    The study of translational control has become increasingly important, as aberrant translation has been linked to the etiology of human diseases. Nevertheless, a convenient research tool to measure and quantify cellular translational activity has not been developed to date. Here we present a translat

  7. [Comparison Analysis of Economic and Engineering Control of Industrial VOCs].

    Science.gov (United States)

    Wang, Yu-fei; Liu, Chang-xin; Cheng, Jie; Hao, Zheng-ping; Wang, Zheng

    2015-04-01

    Volatile organic compounds (VOCs) pollutant has become China's major air pollutant in key urban areas like sulfur dioxide, nitrogen oxides and particulate matter. It is mainly produced from industry sectors, and engineering control is one of the most important reduction measures. During the 12th Five-Year Plan, China decides to invest 40 billion RMB to build pollution control projects in key industry sectors with annual emission reduction of 605 000 t x a(-1). It shows that China attaches a great importance to emission reduction by engineering projects and highlights the awareness of engineering reduction technologies. In this paper, a macroeconomic model, namely computable general equilibrium model, (CGE model) was employed to simulate engineering control and economic control (imposing environmental tax). We aim to compare the pros and cons of the two reduction policies. Considering the economic loss of the whole country, the environmental tax has more impacts on the economy system than engineering reduction measures. We suggest that the central government provides 7 500 RMB x t(-1) as subsidy for enterprises in industry sectors to encourage engineering reduction.

  8. An Analysis of the PLLs With Secondary Control Path

    DEFF Research Database (Denmark)

    Golestan, Saeed; Ramezani, Malek; Guerrero, Josep M.

    2014-01-01

    The phase-locked loops (PLLs) are widely used in different areas of applications particularly for synchronization and control purposes in grid connected applications. A major challenge associated with the PLLs is how to improve their dynamic performance without jeopardizing their stability...

  9. Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

    DEFF Research Database (Denmark)

    Moghimi, Seyed Moien; Hunter, A.C.; Andresen, T.L.

    2012-01-01

    Intravenously injected nanoparticulate drug carriers provide a wide range of unique opportunities for site-specific targeting of therapeutic agents to many areas within the vasculature and beyond. Pharmacokinetics and biodistribution of these carriers are controlled by a complex array of interrel...

  10. Prevalence of HLA-B27 in Moroccan healthy subjects and patients with ankylosing spondylitis and mapping construction of several factors influencing AS diagnosis by using multiple correspondence analysis.

    Science.gov (United States)

    Akassou, Amal; Yacoubi, Hanae; Jamil, Afaf; Dakka, Nadia; Amzazi, Saaïd; Sadki, Khalid; Niamane, Redouane; Elhassani, Selma; Bakri, Youssef

    2015-11-01

    The aim of the present study was to determine the prevalence of human leukocyte antigen HLA-B27 in Moroccan healthy controls and in patients with ankylosing spondylitis (AS), and to analyze the correlation between HLA-B27 and AS in Moroccan patients. The prevalence of HLA-B27 was determined by evaluating the number of HLA-B27-positive samples in 128 healthy subjects and in 53 patients diagnosed with AS according to the ESSG and AMOR criteria. HLA-B27 was determined by the polymerase chain reaction using sequence-specific primers. Multivariate analysis of our data (HLA-B27, age, sex, and family history) for AS and healthy controls was performed by multiple correspondence analysis (MCA). The frequency of HLA-B27 was significantly greater in AS patients (45.3 %) than in healthy controls (4.7 %) [p < 0.0001, OR 16.8, and CI 95 % (5.83-51.03)]. In addition, HLA-B27 was more common in male patients than in female ones (p < 0.05). 100 % of the AS patients reported a family history of AS, whereas only 20 % of the healthy controls reported a family history of AS. The graphical interpretation of MCA showed a significant relation between the presence of HLA-B27 and AS. This study strengthens the link between HLA-B27 and AS and represents a very valuable informative diagnostic tool, especially in regard to male patients who have a family history of AS.

  11. Analysis of Mitochondrial Control Region Using Sanger Sequencing.

    Science.gov (United States)

    Ballard, David

    2016-01-01

    The analysis of mitochondrial DNA (mtDNA) is an established forensic tool and has been used extensively to aid with both the identification of human remains and evidence recovered from scenes of crime. The biology of mtDNA confers both advantages and disadvantages when using it as a tool for identification. It benefits from a high copy number, which facilitates analysis from samples with highly degraded DNA or trace amounts of DNA, but the maternal mode of inheritance restricts its power of discrimination. With Next Generation Sequencing being used in research and some forensic casework laboratories the scope of mtDNA analysis in forensic casework may expand in the near future. Currently, however, most casework laboratories rely on Sanger sequencing and an established method for analyzing the hypervariable sequence regions is described. PMID:27259738

  12. Cultural Meaning of Perceived Control: A Meta-Analysis of Locus of Control and Psychological Symptoms across 18 Cultural Regions

    Science.gov (United States)

    Cheng, Cecilia; Cheung, Shu-fai; Chio, Jasmine Hin-man; Chan, Man-pui Sally

    2013-01-01

    Integrating more than 40 years of studies on locus of control (LOC), this meta-analysis investigated whether (a) the magnitude of the relationship between LOC and psychological symptoms differed among cultures with distinct individualist orientations and (b) depression and anxiety symptoms yielded different patterns of cultural findings with LOC.…

  13. [Research progresses of anabolic steroids analysis in doping control].

    Science.gov (United States)

    Long, Yuanyuan; Wang, Dingzhong; Li, Ke'an; Liu, Feng

    2008-07-01

    Anabolic steroids, a kind of physiological active substance, are widely abused to improve athletic performance in human sports. They have been forbidden in sports by the International Olympic Committee since 1983. Since then, many researchers have been focusing their attentions on the establishment of reliable detection methods. In this paper, we review the research progresses of different analytical methods for anabolic steroids since 2002, such as gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, immunoassay, electrochemistry analysis and mass spectrometry. The developing prospect of anabolic steroids analysis is also discussed.

  14. Application of Multivariable Statistical Techniques in Plant-wide WWTP Control Strategies Analysis

    DEFF Research Database (Denmark)

    Flores Alsina, Xavier; Comas, J.; Rodríguez-Roda, I.;

    2007-01-01

    The main objective of this paper is to present the application of selected multivariable statistical techniques in plant-wide wastewater treatment plant (WWTP) control strategies analysis. In this study, cluster analysis (CA), principal component analysis/factor analysis (PCA/FA) and discriminant...... analysis (DA) are applied to the evaluation matrix data set obtained by simulation of several control strategies applied to the plant-wide IWA Benchmark Simulation Model No 2 (BSM2). These techniques allow i) to determine natural groups or clusters of control strategies with a similar behaviour, ii......) to find and interpret hidden, complex and casual relation features in the data set and iii) to identify important discriminant variables within the groups found by the cluster analysis. This study illustrates the usefulness of multivariable statistical techniques for both analysis and interpretation...

  15. Quality control of raw cows' milk by headspace analysis

    NARCIS (Netherlands)

    Hettinga, K.A.; Valenberg, van H.J.F.; Hooijdonk, van A.C.M.

    2008-01-01

    This study investigated whether headspace analysis of volatile components can be used for monitoring the quality of raw cows¿ milk. The detection of different quality defects caused by cows¿ feed, microbiological and chemical contamination, as well as enzymatic deterioration was studied. Fresh raw m

  16. Computational Analysis for Roughness-Based Transition Control

    Science.gov (United States)

    Li, Fei; Choudhari, Meelan M.; Chang, Chau-Lyan; Edwards, Jack R., Jr.

    2009-01-01

    Suitably placed discrete roughness elements are known to delay or hasten the onset of transition, depending on requirements. In this paper, 2D eigenvalue analysis is used to study the effects of surface roughness in the context of transition delay over subsonic and supersonic swept wing configurations, as well as boundarylayer tripping on the forebody of a hypersonic air breathing vehicle.

  17. Analysis and Modeling of Control Tasks in Dynamic Systems

    DEFF Research Database (Denmark)

    Ursem, Rasmus Kjær; Krink, Thiemo; Jensen, Mikkel Thomas;

    2002-01-01

    -case generators (TCGs), which requires a systematic analysis of dynamic optimization tasks. So far, only a few TCGs have been suggested. Our investigation leads to the conclusion that these TCGs are not capable of generating realistic dynamic benchmark tests. The result of our research is the design of a new TCG...

  18. Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control.

    Science.gov (United States)

    Prohászka, Zoltán; Nilsson, Bo; Frazer-Abel, Ashley; Kirschfink, Michael

    2016-11-01

    In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and C4, has significantly enhanced our understanding of the disease process. Such expanded complement analysis allows for a more precise differential diagnosis and for critical monitoring of complement-targeted therapy. These changes are a result of the growing understanding of the involvement of complement in a diverse set of disorders. To appreciate the importance of proper complement analysis, it is important to understand the role it plays in disease. Historically, it was the absence of complement as manifested in severe infection that was noted. Since then complement has been connected to a variety of inflammatory disorders, such as autoimmune diseases and hereditary angioedema. While the role of complement in the rejection of renal grafts has been known longer, the significant impact of complement. In certain nephropathies has now led to the reclassification of some rare kidney diseases and an increased role for complement analysis in diagnosis. Even more unexpected is that complement has also been implicated in neural, ophtalmological and dermatological disorders. With this level of involvement in some varied and impactful health issues proper complement testing is clearly important; however, analysis of the complement system varies widely among laboratories. Except for a few proteins, such as C3 and C4, there are neither well-characterized standard preparations nor calibrated assays available. This is especially true for the inter-laboratory variation of tests which assess classical, alternative, or lectin pathway function. In addition, there is a need for the standardization of the measurement of complement activation products that are so critical in determining whether clinically relevant complement activation has occurred in vivo. Finally, autoantibodies to complement proteins (e.g. anti-C1q), C3 and C4 convertases (C3 and C4 nephritic factor) or to regulatory proteins

  19. Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control.

    Science.gov (United States)

    Prohászka, Zoltán; Nilsson, Bo; Frazer-Abel, Ashley; Kirschfink, Michael

    2016-11-01

    In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and C4, has significantly enhanced our understanding of the disease process. Such expanded complement analysis allows for a more precise differential diagnosis and for critical monitoring of complement-targeted therapy. These changes are a result of the growing understanding of the involvement of complement in a diverse set of disorders. To appreciate the importance of proper complement analysis, it is important to understand the role it plays in disease. Historically, it was the absence of complement as manifested in severe infection that was noted. Since then complement has been connected to a variety of inflammatory disorders, such as autoimmune diseases and hereditary angioedema. While the role of complement in the rejection of renal grafts has been known longer, the significant impact of complement. In certain nephropathies has now led to the reclassification of some rare kidney diseases and an increased role for complement analysis in diagnosis. Even more unexpected is that complement has also been implicated in neural, ophtalmological and dermatological disorders. With this level of involvement in some varied and impactful health issues proper complement testing is clearly important; however, analysis of the complement system varies widely among laboratories. Except for a few proteins, such as C3 and C4, there are neither well-characterized standard preparations nor calibrated assays available. This is especially true for the inter-laboratory variation of tests which assess classical, alternative, or lectin pathway function. In addition, there is a need for the standardization of the measurement of complement activation products that are so critical in determining whether clinically relevant complement activation has occurred in vivo. Finally, autoantibodies to complement proteins (e.g. anti-C1q), C3 and C4 convertases (C3 and C4 nephritic factor) or to regulatory proteins

  20. VCSELs with optically controlled current confinement: experiments and analysis

    Science.gov (United States)

    Bader, Sven; Gerlach, Philipp; Michalzik, Rainer

    2016-04-01

    We have devised a novel oxide-free and regrowth-free approach for optically controlled current confinement in vertical-cavity surface-emitting lasers (VCSELs). This is realized with a monolithically integrated phototransistor (PT), which is configured as an optical switch and embedded between the two Bragg reflectors. We have fabricated functional PT-VCSELs by one-step epitaxial growth plus metal deposition with different top contact sizes. We present light-current-voltage characteristics of the lasers as well as a simple theoretical model explaining the occurrence of a distinct turn-on point and clarify epitaxial design requirements to reach strong optically controlled current confinement.

  1. Vehicle-manipulator systems modeling for simulation, analysis, and control

    CERN Document Server

    From, Pal Johan; Pettersen, Kristin Ytterstad

    2014-01-01

    Furthering the aim of reducing human exposure to hazardous environments, this monograph presents a detailed study of the modeling and control of vehicle-manipulator systems. The text shows how complex interactions can be performed at remote locations using systems that combine the manipulability of robotic manipulators with the ability of mobile robots to locomote over large areas.  The first part studies the kinematics and dynamics of rigid bodies and standard robotic manipulators and can be used as an introduction to robotics focussing on robust mathematical modeling. The monograph then moves on to study vehicle-manipulator systems in great detail with emphasis on combining two different configuration spaces in a mathematically sound way. Robustness of these systems is extremely important and Modeling and Control of Vehicle-manipulator Systems effectively represents the dynamic equations using a mathematically robust framework. Several tools from Lie theory and differential geometry are used to obtain glob...

  2. Component-based analysis of embedded control applications

    DEFF Research Database (Denmark)

    Angelov, Christo K.; Guan, Wei; Marian, Nicolae;

    2011-01-01

    The widespread use of embedded systems requires the creation of industrial software technology that will make it possible to engineer systems being correct by construction. That can be achieved through the use of validated (trusted) components, verification of design models, and automatic...... configuration of applications from validated design models and trusted components. This design philosophy has been instrumental for developing COMDES—a component-based framework for distributed embedded control systems. A COMDES application is conceived as a network of embedded actors that are configured from...... instances of reusable, executable components—function blocks (FBs). System actors operate in accordance with a timed multitasking model of computation, whereby I/O signals are exchanged with the controlled plant at precisely specified time instants, resulting in the elimination of I/O jitter. The paper...

  3. Bifurcation Analysis of a Discrete Logistic System with Feedback Control

    Institute of Scientific and Technical Information of China (English)

    WU Dai-yong

    2015-01-01

    The paper studies the dynamical behaviors of a discrete Logistic system with feedback control. The system undergoes Flip bifurcation and Hopf bifurcation by using the center manifold theorem and the bifurcation theory. Numerical simulations not only illustrate our results, but also exhibit the complex dynamical behaviors of the system, such as the period-doubling bifurcation in periods 2, 4, 8 and 16, and quasi-periodic orbits and chaotic sets.

  4. Pollution Control Policies and Natural Resource Dynamics: A Theoretical Analysis

    OpenAIRE

    Rinaldi, S.; W.C. Sanderson; Gragnani, A.

    1995-01-01

    Policies for the management of natural resources and the resources themselves interact to form complex systems. In this paper, we present a highly simplified model that can be used to study the general features of those systems. The model has three state variables, the abundance of the resource, environmental pollution, and the capital devoted to pollution control. We analyze it graphically using the singular perturbation approach. Two modes of behavior are possible, stationary and cyclic. Wh...

  5. Functional output-controllability analysis of fixed speed wind turbine

    OpenAIRE

    Domínguez García, José Luís; García Planas, María Isabel

    2013-01-01

    This paper deals with the concepts of functional output-controllability character of a finite-dimensional linear dynamical system. And a method for comput- ing the functional outputcontrollability consisting on the calculation of the rank of a certain constant ma- trix related to the system dynamics is introduced. The linear system under study is a fixed speed wind tur- bine (FSWT) formed by a squirrel cage generator con- nected directly to the grid. Due to the non-lin...

  6. Comparative analysis of alcohol control policies in 30 countries.

    OpenAIRE

    BRAND Donald A.; Michaela Saisana; RYNN Lisa A.; Fulvia Pennoni; Lowenfels, Albert B.

    2007-01-01

    BACKGROUND: Alcohol consumption causes an estimated 4% of the global disease burden, prompting governments to impose regulations to mitigate the adverse effects of alcohol. To assist public health leaders and policymakers, the authors developed a composite indicator-the Alcohol Policy Index-to gauge the strength of a country's alcohol control policies. METHODS AND FINDINGS: The Index generates a score based on policies from five regulatory domains-physical availability of alcohol, drinking co...

  7. Comparative Analysis of Alcohol Control Policies in 30 Countries

    OpenAIRE

    BRAND Donald A.; SAISANA MICHAELA; RYNN Lisa A.; Pennoni, Fulvia; Lowenfels, Albert B.

    2007-01-01

    BACKGROUND. Alcohol consumption causes an estimated 4% of the global disease burden, prompting governments to impose regulations to mitigate the adverse effects of alcohol. To assist public health leaders and policymakers, we developed a composite indicator¿the Alcohol Policy Index¿to gauge the strength of a country's alcohol control policies. METHODOLOGY/PRINCIPAL FINDINGS. The Index generates a score based on policies from 5 regulatory domains¿physical availability of alcohol, drinkin...

  8. Analysis of the environmental control technology for tar sand development

    Energy Technology Data Exchange (ETDEWEB)

    de Nevers, N.; Glenne, B.; Bryner, C.

    1979-06-01

    The environmental technology for control of air pollution, water pollution, and for the disposal, stabilization, and vegetation of the waste tar sand were thoroughly investigated. Although some difficulties may be encountered in any of these undertakings, it seems clear that the air and water pollution problems can be solved to meet any applicable standard. Currently there are two large-scale plants producing liquid fuels from tar sands in Alberta, Canada which use similar technology involving surface mining, hot water extraction, and surface disposal of waste sand. These projects all meet the Canadian environmental control regulations in force at the time they began. The largest US deposits of tar sands are much smaller than the Canadian; 95 percent are located in the state of Utah. Their economics do not appear as attractive as the Canadian deposits. The environmental control costs are not large enough to make an otherwise economic project uneconomic. The most serious environmental conflict likely to occur over the recovery of liquid fuels from the US deposits of tar sands is that caused by the proximity of the deposits to national parks, national monuments, and a national recreation area in Utah. These areas have very stringent air pollution requirements; and even if the air pollution control requirements can be met, there may still be adequate opposition to large-scale mining ventures in these areas to prevent their commercial exploitation. Another environmental constraint may be water rights availability.Essentially all of the water running in the Colorado river basin is now legally allocated. Barring new interpretations of the legality of water rights purchase, Utah tar sands developments should be able to obtain water by purchasing existing irrigation water rights.

  9. Control Systems with Saturating Inputs Analysis Tools and Advanced Design

    CERN Document Server

    Corradini, Maria Letizia; Giannoni, Fabio; Orlando, Giuseppe

    2012-01-01

    This series aims to report new developments in the fields of control and information sciences - quickly, informally and at a high level. The type of material considered for publication includes: 1. Preliminary drafts of monographs and advanced textbooks 2. Lectures on a new field, or presenting a new angle on a classical field 3. Research reports 4. Reports of meetings, provided they are a) of exceptional interest and b) devoted to a specific topic. The timeliness of subject material is very important.

  10. Analysis of Setups of the Control of Rail Microprocessor Systems

    Directory of Open Access Journals (Sweden)

    Mieczyslaw Kornaszewski

    2008-01-01

    Full Text Available In the article will have been introduced possibilities following from the application of the microprocessor technology in rail systems of the control of traffic will remain for example of modern signalling on railway crossings. Introduction to microcomputer and microprocessor systems of rail devices will permit to eliminate and to replace disusedrelay devices with them and raising safety on railway and increasing reliability of used devices.

  11. Analysis of Control Strategies for Diode Clamped Multilevel Inverter

    OpenAIRE

    C. R. Balamurugan; S. P. NATARAJAN; R. Revathy

    2013-01-01

    This paper presents the comparison of various Pulse Width Modulation (PWM) strategies for the three phase Diode Clamped Multi Level Inverter (DCMLI). The main contribution of this paper is the proposal of new modulation schemes with Variable Amplitude (VA) and various new schemes adopting the constant switching frequency and also variable switching frequency multicarrier control freedom degree combination concepts are developed and simulated for the chosen three phase DCMLI. The three phase D...

  12. Impact analysis of different operation strategies for battery energy storage systems (BESS) providing primary control reserve

    OpenAIRE

    Fleer, Johannes; Stenzel, Peter; Linssen, Jochen

    2015-01-01

    In this work, a techno-economic analysis of stationary battery systems providing primary control for grid stabilisation is conducted. The effects of battery design and operation strategies adapted for primary control supply are investigated with regard to costs and parameters relevant for battery aging. Primary control is required to balance the feed-in and use of electricity to/from the grid, thereby ensuring safe and stable grid operation. In Germany, primary control is traded on a separate...

  13. Modeling, analysis and control of fuel cell hybrid power systems

    Science.gov (United States)

    Suh, Kyung Won

    Transient performance is a key characteristic of fuel cells, that is sometimes more critical than efficiency, due to the importance of accepting unpredictable electric loads. To fulfill the transient requirement in vehicle propulsion and portable fuel cell applications, a fuel cell stack is typically coupled with a battery through a DC/DC converter to form a hybrid power system. Although many power management strategies already exist, they all rely on low level controllers that realize the power split. In this dissertation we design controllers that realize various power split strategies by directly manipulating physical actuators (low level commands). We maintain the causality of the electric dynamics (voltage and current) and investigate how the electric architecture affects the hybridization level and the power management. We first establish the performance limitations associated with a stand-alone and power-autonomous fuel cell system that is not supplemented by an additional energy storage and powers all its auxiliary components by itself. Specifically, we examine the transient performance in fuel cell power delivery as it is limited by the air supplied by a compressor driven by the fuel cell itself. The performance limitations arise from the intrinsic coupling in the fluid and electrical domain between the compressor and the fuel cell stack. Feedforward and feedback control strategies are used to demonstrate these limitations analytically and with simulations. Experimental tests on a small commercial fuel cell auxiliary power unit (APU) confirm the dynamics and the identified limitations. The dynamics associated with the integration of a fuel cell system and a DC/DC converter is then investigated. Decentralized and fully centralized (using linear quadratic techniques) controllers are designed to regulate the power system voltage and to prevent fuel cell oxygen starvation. Regulating these two performance variables is a difficult task and requires a compromise

  14. Analysis and control of computer cooling fan noise

    Science.gov (United States)

    Wong, Kam

    This thesis is divided into three parts: the study of the source mechanisms and their separation, passive noise control, and active noise control. The mechanisms of noise radiated by a typical computer cooling fan is investigated both theoretically and experimentally focusing on the dominant rotor-stator interaction. The unsteady force generated by the aerodynamic interaction between the rotor blades and struts is phase locked with the blade rotation and radiates tonal noise. Experimentally, synchronous averaging with the rotation signal extracts the tones made by the deterministic part of the rotor-strut interaction mechanism. This averaged signal is called the rotary noise. The difference between the overall noise and rotary noise is defined as random noise which is broadband in the spectrum. The deterministic tonal peaks are certainly more annoying than the broadband, so the suppression of the tones is the focus of this study. Based on the theoretical study of point force formulation, methods are devised to separate the noise radiated by the two components of drag and thrust forces on blades and struts. The source separation is also extended to the leading and higher order modes of the spinning pressure pattern. By using the original fan rotor and installing it in various casings, the noise sources of the original fan are decomposed into elementary sources through directivity measurements. Details of the acoustical directivity for the original fan and its various modifications are interpreted. For the sample fan, two common features account for most of the tonal noise radiated. The two features are the inlet flow distortion caused by the square fan casing, and the large strut carrying the electric wires for the motor. When the inlet bellmouth is installed and the large strut is trimmed down to size, a significant reduction of 12 dB in tonal sound power is achieved. These structural corrections constitute the passive noise control. However, the end product still

  15. Analysis and control of excitation, field weakening and stability in direct torque controlled electrically excited synchronous motor drives

    Energy Technology Data Exchange (ETDEWEB)

    Pyrhoenen, O.

    1998-12-31

    Direct torque control (DTC) is a new control method for rotating field electrical machines. DTC controls directly the motor stator flux linkage with the stator voltage, and no stator current controllers are used. With the DTC method very good torque dynamics can be achieved. Until now, DTC has been applied to asynchronous motor drives. The purpose of this work is to analyse the applicability of DTC to electrically excited synchronous motor drives. Compared with asynchronous motor drives, electrically excited synchronous motor drives require an additional control for the rotor field current. The field current control is called excitation control in this study. The dependence of the static and dynamic performance of DTC synchronous motor drives on the excitation control has been analysed and a straightforward excitation control method has been developed and tested. In the field weakening range the stator flux linkage modulus must be reduced in order to keep the electro motive force of the synchronous motor smaller than the stator voltage and in order to maintain a sufficient voltage reserve. The dynamic performance of the DTC synchronous motor drive depends on the stator flux linkage modulus. Another important factor for the dynamic performance in the field weakening range is the excitation control. The field weakening analysis considers both dependencies. A modified excitation control method, which maximises the dynamic performance in the field weakening range, has been developed. In synchronous motor drives the load angle must be kept in a stabile working area in order to avoid loss of synchronism. The traditional vector control methods allow to adjust the load angle of the synchronous motor directly by the stator current control. In the DTC synchronous motor drive the load angle is not a directly controllable variable, but it is formed freely according to the motor`s electromagnetic state and load. The load angle can be limited indirectly by limiting the torque

  16. Modeling, Analysis, and Control of Demand Response Resources

    Energy Technology Data Exchange (ETDEWEB)

    Mathieu, Johanna L. [Univ. of California, Berkeley, CA (United States)

    2012-05-01

    While the traditional goal of an electric power system has been to control supply to fulfill demand, the demand-side can plan an active role in power systems via Demand Response (DR), defined by the Department of Energy (DOE) as “a tariff or program established to motivate changes in electric use by end-use customers in response to changes in the price of electricity over time, or to give incentive payments designed to induce lower electricity use at times of high market prices or when grid reliability is jeopardized” [29]. DR can provide a variety of benefits including reducing peak electric loads when the power system is stressed and fast timescale energy balancing. Therefore, DR can improve grid reliability and reduce wholesale energy prices and their volatility. This dissertation focuses on analyzing both recent and emerging DR paradigms. Recent DR programs have focused on peak load reduction in commercial buildings and industrial facilities (C&I facilities). We present methods for using 15-minute-interval electric load data, commonly available from C&I facilities, to help building managers understand building energy consumption and ‘ask the right questions’ to discover opportunities for DR. Additionally, we present a regression-based model of whole building electric load, i.e., a baseline model, which allows us to quantify DR performance. We use this baseline model to understand the performance of 38 C&I facilities participating in an automated dynamic pricing DR program in California. In this program, facilities are expected to exhibit the same response each DR event. We find that baseline model error makes it difficult to precisely quantify changes in electricity consumption and understand if C&I facilities exhibit event-to-event variability in their response to DR signals. Therefore, we present a method to compute baseline model error and a metric to determine how much observed DR variability results from baseline model error rather than real

  17. Controlling the sense of molecular rotation: classical vs quantum analysis

    CERN Document Server

    Khodorkovsky, Yuri; Hasegawa, Hirokazu; Ohshima, Yasuhiro; Averbukh, Ilya Sh

    2010-01-01

    Recently, it was predicted theoretically and verified experimentally that a pair of delayed and cross-polarized short laser pulses can create molecular ensembles with a well defined sense of rotation (clockwise or counterclockwise). Here we provide a comparative study of the classical and quantum aspects of the underlying mechanism for linear molecules and for symmetric tops, like benzene molecules, that were used for the first experimental demonstration of the effect. Very good quantitative agreement is found between the classical description of the process and the rigorous quantum mechanical analysis at the relevant experimental conditions. Both approaches predict the same optimal values for the delay between pulses and the angle between them, and deliver the same magnitude of the induced oriented angular momentum of the molecular ensemble. As expected, quantum and classical analysis substantially deviate when the delay between pulses is comparable with the period of quantum rotational revivals. However, ti...

  18. Development of Photogrammetric Methods of Stress Analysis and Quality Control

    CERN Document Server

    Kubik, D L; Kubik, Donna L.; Greenwood, John A.

    2003-01-01

    A photogrammetric method of stress analysis has been developed to test thin, nonstandard windows designed for hydrogen absorbers, major components of a muon cooling channel. The purpose of the absorber window tests is to demonstrate an understanding of the window behavior and strength as a function of applied pressure. This is done by comparing the deformation of the window, measured via photogrammetry, to the deformation predicted by finite element analysis (FEA). FEA analyses indicate a strong sensitivity of strain to the window thickness. Photogrammetric methods were chosen to measure the thickness of the window, thus providing data that are more accurate to the FEA. This, plus improvements made in hardware and testing procedures, resulted in a precision of 5 microns in all dimensions and substantial agreement with FEA predictions.

  19. Electromagnetic analysis of electromagnet for control element drive mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Huh, Hyung; Kim, J.I.; Kim, J.H.; Kim, Y.W. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-06-01

    A 2-D electromagnetic numerical analysis model is developed to calculate the attraction force of the electromagnet for CEDM. trend relating to electromagnetic design within constrained. The important design variables of the electromagnet are current density and air gap length. The results show that the attraction force by using optimum design point is well within the acceptable level. It is anticipated that the results will eventually be utilized for more realitic design of the electromagnet. 10 refs., 38 figs., 2 tabs. (Author)

  20. Analysis of the environmental control technology for oil shale development

    Energy Technology Data Exchange (ETDEWEB)

    de Nevers, N.; Eckhoff, D.; Swanson, S.; Glenne, B.; Wagner, F.

    1978-02-01

    The environmental control technology proposed in the various oil shale projects which are under development are examined. The technologies for control of air pollution, water pollution, and for the disposal, stabilization, and vegetation of the processed shale were thoroughly investigated. Although some difficulties may be encountered in any of these undertakings, it seems clear that the air and water pollution problems can be solved to meet any applicable standard. There are no published national standards against which to judge the stabilization and vegetation of the processed shale. However, based on the goal of producing an environmentally and aesthetically acceptable finished processed shale pile, it seems probable that this can be accomplished. It is concluded that the environmental control technology is available to meet all current legal requirements. This was not the case before Colorado changed their applicable Air Pollution regulations in August of 1977; the previous ones for the oil shale region were sufficiently stringent to have caused a problem for the current stage of oil shale development. Similarly, the federal air-quality, non-deterioration regulations could be interpreted in the future in ways which would be difficult for the oil shale industry to comply with. The Utah water-quality, non-deterioration regulations could also be a problem. Thus, the only specific regulations which may be a problem are the non-deterioration parts of air and water quality regulations. The unresolved areas of environmental concern with oil shale processing are mostly for the problems not covered by existing environmental law, e.g., trace metals, polynuclear organics, ground water-quality changes, etc. These may be problems, but no evidence is yet available that these problems will prevent the successful commercialization of oil shale production.

  1. Economic Analysis of HPAI Control in the Netherlands II: Comparison of Control Strategies

    NARCIS (Netherlands)

    Longworth, N.J.; Mourits, Monique C.M.; Saatkamp, H.W.

    2014-01-01

    A combined epidemiological-economic modelling approach was used to analyse strategies for highly pathogenic avian influenza (HPAI) control for the Netherlands. The modelling framework used was InterSpread Plus (ISP), a spatially based, stochastic and dynamic simulation model. A total of eight contro

  2. Free and moving boundaries analysis, simulation and control

    CERN Document Server

    Glowinski, Roland

    2007-01-01

    Optimal Tubes: Geodesic Metric, Euler Flow, Moving Domain J.P. Zolésio Numerical Simulation of Pattern Formation in a Rotating Suspension of Non-Brownian Settling Particles Tsorg-Whay Pan and Roland Glowinski On the Homogenization of Optimal Control Problems on Periodic Graphs P.I. Kogut and G. Leugering Lift and Sedimentation of Particles in the Flow of a Viscoelastic Liquid in a Channel G.P. Galdi and V. Heuveline Modeling and Simulation of Liquid-Gas Free Surface Flows A. Caboussat, M.

  3. Analysis and Design of Embedded Controlled Parallel Resonant Converter

    Directory of Open Access Journals (Sweden)

    P. CHANDRASEKHAR

    2009-07-01

    Full Text Available Microcontroller based constant frequency controlled full bridge LC parallel resonant converter is presented in this paper for electrolyser application. An electrolyser is a part of renewable energy system which generates hydrogen from water electrolysis. The DC power required by the electrolyser system is supplied by the DC-DC converter. Owing to operation under constant frequency, the filter designs are simplified and utilization of magnetic components is improved. This converter has advantages like high power density, low EMI and reduced switching stresses. DC-DC converter system is simulated using MATLAB, Simulink. Detailed simulation results are presented. The simulation results are compared with the experimental results.

  4. Quantitative detection and differentiation of free-living amoeba species using SYBR green-based real-time PCR melting curve analysis.

    Science.gov (United States)

    Behets, Jonas; Declerck, Priscilla; Delaedt, Yasmine; Verelst, Lieve; Ollevier, Frans

    2006-12-01

    Real-time polymerase chain reaction melting curve analysis (MCA) allows differentiation of several free-living amoebae species. Distinctive characteristics were found for Naegleria fowleri, N. lovaniensis, N. australiensis, N. gruberi, Hartmanella vermiformis, and Willaertia magna. Species specificity of the amplicons was confirmed using agarose gel electrophoresis and sequence-based approaches. Amplification efficiency ranged from 91% to 98%, indicating the quantitative potential of the assay. This MCA approach can be used for quantitative detection of free-living amoebae after cultivation but also as a culture-independent detection method.

  5. Stability Analysis of Some Nonlinear Feedback Control Methods for Beam Halo-Chaos Suppression

    Institute of Scientific and Technical Information of China (English)

    FANG Jin-Qing; WANG Zhong-Sheng; CHEN Guan-Rong

    2004-01-01

    Control of beam halo-chaos has been a very challenging subject for research in recent years, in which some nonlinear feedback methods have been developed for suppression of beam halo-chaos in high-current proton linear accelerators. However, stability analysis of such successful nonlinear feedback control methods has not yet been rigorously carried out, which remains an important open topic in the field. In this letter, we present a rigorous mathematical analysis of several nonlinear feedback control methods that are applied to control beam halo-chaos with great success on simulations.

  6. Stability Analysis of Some Nonlinear Feedback Control Methods for Beam Halo-ChaosSuppression

    Institute of Scientific and Technical Information of China (English)

    FANGJin-Qing; WANGZhong-Sheng; CHENGuan-Rong

    2004-01-01

    Control of beam halo-chaos has been a very challenging subject for research in recent years, in which some nonlinear feedback methods have been developed for suppression of beam halo-chaos in high-current proton linear accelerators. However, stability analysis of such successful nonlinear feedback control methods has not yet been rigorously carried out, which remains an important open topic in the field. In this letter, we present a rigorous mathematical analysis of several nonlinear feedback control methods that are applied to control beam halo-chaos with great success on simulations.

  7. SUPERCONVERGENCE ANALYSIS OF FINITE ELEMENT METHODS FOR OPTIMAL CONTROL PROBLEMS OF THE STATIONARY BENARD TYPE

    Institute of Scientific and Technical Information of China (English)

    Yanzhen Chang; Danping Yang

    2008-01-01

    In this paper, we consider the finite element approximation of the distributed optimal control problems of the stationary Bénard type under the pointwise control constraint. The states and the co-states are approximated by polynomial functions of lowest-order mixed finite element space or piecewise linear functions and the control is approximated by piecewise constant functions. We give the superconvergence analysis for the control; it is proved that the approximation has a second-order rate of convergence. We further give the superconvergence analysis for the states and the co-states. Then we derive error estimates in L∞-norm and optimal error estimates in L2-norm.

  8. Negative Control Outcomes and the Analysis of Standardized Mortality Ratios.

    Science.gov (United States)

    Richardson, David B; Keil, Alexander P; Tchetgen Tchetgen, Eric; Cooper, Glinda

    2015-09-01

    In occupational cohort mortality studies, epidemiologists often compare the observed number of deaths in the cohort to the expected number obtained by multiplying person-time accrued in the study cohort by the mortality rate in an external reference population. Interpretation of the result may be difficult due to noncomparability of the occupational cohort and reference population with respect to unmeasured risk factors for the outcome of interest. We describe an approach to estimate an adjusted standardized mortality ratio (aSMR) to control for such bias. The approach draws on methods developed for the use of negative control outcomes. Conditions necessary for unbiased estimation are described, as well as looser conditions necessary for bias reduction. The approach is illustrated using data on bladder cancer mortality among male Oak Ridge National Laboratory workers. The SMR for bladder cancer was elevated among hourly-paid males (SMR = 1.9; 95% confidence interval [CI] = 1.3, 2.7) but not among monthly-paid males (SMR = 1.0; 95% CI = 0.67, 1.3). After indirect adjustment using the proposed approach, the mortality ratios were similar in magnitude among hourly- and monthly-paid men (aSMR = 2.2; 95% CI = 1.5, 3.2; and, aSMR = 2.0; 95% CI = 1.4, 2.8, respectively). The proposed adjusted SMR offers a complement to typical SMR analyses.

  9. COMPLICATION ANALYSIS OF INTRACRANIAL ANEURYSM EMBOLIZATION WITH CONTROLLABLE COILS

    Institute of Scientific and Technical Information of China (English)

    王大明; 凌锋; 王安顺

    2004-01-01

    Objective To explore the causes, prevention, and management of the complications during intracranial aneurysm embolization with controllable coils (mechanical detachable spiral, MDS; and Guglielmi detachable coil, GDC). Methods Retrospective review of 120 cases with 125 intracranial aneurysms embolized with controllable coils from March 1995 to July 1999 was conducted. The 20 accidents (in 18 cases) including aneurysm rupture, over-embolization, protrusion of coil end into the parent artery, and thrombosis of the parent artery were analyzed. Results Among the 20 accidents, there were 6 aneurysm ruptures, 6 over-embolizations (in 5cases), 6 coil protrusions, and 2 thromboses (one was secondary to coil protrusion). The embolizationrelated mortality was 3.33% (4/120), the permanent neurological deficit was 1.67% (2/120), and the transitory neurological deficit was 3.33% (4/120). The occurrence and outcome of the complications were related to the embolizing technique, the pattern of aneurysm and its parent artery, the imperfection of embolic materials, and the observation and management during embolization. Conclusion Skilled embolizing technique, better understanding of the angio-anatomy of an aneurysm and its parent artery, correct judgement and management during embolization, and improvement of embolic materials are beneficial to the reduction of complications and to the melioration of the outcome of complications.

  10. A retrospective mathematical analysis of controlled release design and experimentation.

    Science.gov (United States)

    Rothstein, Sam N; Kay, Jennifer E; Schopfer, Francisco J; Freeman, Bruce A; Little, Steven R

    2012-11-01

    The development and performance evaluation of new biodegradable polymer controlled release formulations relies on successful interpretation and evaluation of in vitro release data. However, depending upon the extent of empirical characterization, release data may be open to more than one qualitative interpretation. In this work, a predictive model for release from degradable polymer matrices was applied to a number of published release data in order to extend the characterization of release behavior. Where possible, the model was also used to interpolate and extrapolate upon collected released data to clarify the overall duration of release and also kinetics of release between widely spaced data points. In each case examined, mathematical predictions of release coincide well with experimental results, offering a more definitive description of each formulation's performance than was previously available. This information may prove particularly helpful in the design of future studies, such as when calculating proper dosing levels or determining experimental end points in order to more comprehensively evaluate a controlled release system's performance.

  11. The use of lac-type promoters in control analysis

    DEFF Research Database (Denmark)

    Jensen, Peter Ruhdal; Westerhoff, H. v.; Michelsen, Ole

    1993-01-01

    , the tacI promoter when the latter is high. The endogenous lac operon is placed under the control of a second copy of the lacUV5 promoter and a lacYam mutation (eliminating lactose permease, the transport system for the inducer isopropyl-thio-beta-D-galactoside) is introduced. The method was demonstrated...... experimentally by constructing E. coli strains, in which the chromosomal atp operon is transcribed from the lacUV5 and the tacI promoter. We measured the concentration of the c subunit of H+-ATPase, and found that the expression of this enzyme could be modulated between non-detectable levels and up to five times...... the wild-type level. Thus, in the absence of inducer, no expression of atp genes could be detected when the atp operon was controlled by the lacUV5 promoter, and we estimate that the expression was less than 0.0025 times the wild-type level. We show that the introduction of a lac Y mutation facilitated...

  12. Semi-active vibration control based on unsymmetrical synchronized switch damping: Analysis and experimental validation of control performance

    Science.gov (United States)

    Ji, Hongli; Qiu, Jinhao; Cheng, Li; Nie, Hong

    2016-05-01

    In semi-active synchronized switch damping (SSD) approaches for structural vibration control, the damping effect is achieved by properly switching the voltage on the piezoelectric actuators. Unsymmetrical SSD switch circuit has been designed in the previous paper to increase the effective voltage range on the PZT actuator for improvement of the control performance. In this study, analysis and experimental validation of control performance of a synchronized switch damping system based on the unsymmetrical switch circuit are carried out. First the model of an unsymmetrical SSD system is presented and the working principle is introduced. The general expression of the switched voltage on the piezoelectric actuator is derived. Based on its periodicity in steady-state control, the harmonic components of the actuator voltage are derived using Fourier series expansion. Next, the displacement response of the system is derived under combined actions of the excitation and switched voltage. Finally, a setup of a flexible beam with unsymmetrical switch circuit is used to demonstrate the control performance under different voltage sources and to verify the theoretical results. The results show that the control performance mainly depends on the voltage range on the PZT. A higher effective voltage range can be generated in unsymmetrical SSDV than in symmetrical SSDV and better control performance can be achieved at the same negative actuator voltage. The unsymmetrical SSDV makes better utilization of the actuator capability.

  13. Performance Analysis of a DTC and SVM Based Field-Orientation Control Induction Motor Drive

    Directory of Open Access Journals (Sweden)

    Md. Rashedul Islam

    2015-02-01

    Full Text Available This study presents a performance analysis of two most popular control strategies for Induction Motor (IM drives: direct torque control (DTC and space vector modulation (SVM strategies. The performance analysis is done by applying field-orientation control (FOC technique because of its good dynamic response. The theoretical principle, simulation results are discussed to study the dynamic performances of the drive system for individual control strategies using actual parameters of induction motor. A closed loop PI controller scheme has been used. The main purpose of this study is to minimize ripple in torque response curve and to achieve quick speed response as well as to investigate the condition for optimum performance of induction motor drive. Depending on the simulation results this study also presents a detailed comparison between direct torque control and space vector modulation based field-orientation control method for the induction motor drive.

  14. Analysis of Laser-encoding Remote-control Explosive System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    According to the requirements, an active infrared system is designed, which is composed of the emitting and receiving parts. The emitting part consists of a GaAs semiconductor laser device and binoculars optical system. A Si photodiode is selected as the receiving device, and a preamplifier circuit is designed to match the detector and further improve the signal to noise ratio. The laser-encoding mode is utilized to enhance the anti-disturbance. The theoretical analysis of this system is presented and a system prototype is made according to the requirement. The experimental results agree well with the theoretical prediction.

  15. Computational issue in the analysis of adaptive control systems

    Science.gov (United States)

    Kosut, Robert L.

    1989-01-01

    Adaptive systems under slow parameter adaption can be analyzed by the method of averaging. This provides a means to assess stability (and instability) properties of most adaptive systems, either continuous-time or (more importantly for practice) discrete-time, as well as providing an estimate of the region of attraction. Although the method of averaging is conceptually straightforward, even simple examples are well beyond hand calculations. Specific software tools are proposed which can provide the basis for user-friendly environment to perform the necessary computations involved in the averaging analysis.

  16. Modeling, Analysis, and Control of Demand Response Resources

    Energy Technology Data Exchange (ETDEWEB)

    Mathieu, Johanna L. [Univ. of California, Berkeley, CA (United States)

    2012-05-01

    While the traditional goal of an electric power system has been to control supply to fulfill demand, the demand-side can plan an active role in power systems via Demand Response (DR), defined by the Department of Energy (DOE) as “a tariff or program established to motivate changes in electric use by end-use customers in response to changes in the price of electricity over time, or to give incentive payments designed to induce lower electricity use at times of high market prices or when grid reliability is jeopardized” [29]. DR can provide a variety of benefits including reducing peak electric loads when the power system is stressed and fast timescale energy balancing. Therefore, DR can improve grid reliability and reduce wholesale energy prices and their volatility. This dissertation focuses on analyzing both recent and emerging DR paradigms. Recent DR programs have focused on peak load reduction in commercial buildings and industrial facilities (C&I facilities). We present methods for using 15-minute-interval electric load data, commonly available from C&I facilities, to help building managers understand building energy consumption and ‘ask the right questions’ to discover opportunities for DR. Additionally, we present a regression-based model of whole building electric load, i.e., a baseline model, which allows us to quantify DR performance. We use this baseline model to understand the performance of 38 C&I facilities participating in an automated dynamic pricing DR program in California. In this program, facilities are expected to exhibit the same response each DR event. We find that baseline model error makes it difficult to precisely quantify changes in electricity consumption and understand if C&I facilities exhibit event-to-event variability in their response to DR signals. Therefore, we present a method to compute baseline model error and a metric to determine how much observed DR variability results from baseline model error rather than real

  17. Preparation of Internal Quality Control Material for Lymphocyte Subset Analysis.

    Science.gov (United States)

    Roh, Eun Youn; Shin, Sue; Yoon, Jong Hyun; Oh, Sohee; Park, Kyoung Un; Lee, Nuri; Song, Eun Young

    2016-07-01

    Lymphocyte subset analysis is widely used in clinical laboratories, and more than two levels of daily QC materials are required for reliable results. Commercially available, expensive QC materials have short shelf lives and may not be suitable in resource-poor settings. We compared different methods for preparing homemade QC material, including fixation with 1%, 2%, or 4% paraformaldehyde (PFA); freezing with 10% dimethylsulfoxide (DMSO), 0.1% bovine serum albumin-phosphate buffered saline, or after ethanolic dehydration; and using cryopreservation temperatures of -20°C, -80°C, or -196°C. We found an optimal experimental condition, which is 'fixation with 4% PFA, freezing with 10% DMSO, and storage at 80°C'. To evaluate long-term stability of QC materials prepared in this optimal condition, two levels of QC materials (QM1 and QM2) were thawed after 30, 33, 35, 37, 60, 62, 64, and 67 days of cryopreservation. Lymphocyte subset was analyzed with BD Multitest IMK kit (BD Biosciences, USA). QM1 and QM2 were stable after 1-2 months of cryopreservation (CV materials for lymphocyte subset analysis in resource-poor settings.

  18. Flexible aircraft dynamic modeling for dynamic analysis and control synthesis

    Science.gov (United States)

    Schmidt, David K.

    1989-01-01

    The linearization and simplification of a nonlinear, literal model for flexible aircraft is highlighted. Areas of model fidelity that are critical if the model is to be used for control system synthesis are developed and several simplification techniques that can deliver the necessary model fidelity are discussed. These techniques include both numerical and analytical approaches. An analytical approach, based on first-order sensitivity theory is shown to lead not only to excellent numerical results, but also to closed-form analytical expressions for key system dynamic properties such as the pole/zero factors of the vehicle transfer-function matrix. The analytical results are expressed in terms of vehicle mass properties, vibrational characteristics, and rigid-body and aeroelastic stability derivatives, thus leading to the underlying causes for critical dynamic characteristics.

  19. Computational Analysis of Cryogenic Flow Through a Control Valve

    Science.gov (United States)

    Danes, Russell; Woods, Jody; Sulyma, Peter

    2003-01-01

    The initial efforts to develop the capability to model valves used in rocket engine component testing at Stennis Space Center are documented. An axisymmetric model of a control valve with LN2 as the working fluid was developed. The goal was to predict the effect of change in the plug/sear region of the valve prior to testing. The valve flow coefficient was predicted for a range of plug positions. Verification of the calculations was carried out to quantify the uncertainty in the numerical answer. The modeled results compared well qualitatively to experimental trends. Additionally, insights into the flow processes in the valve were obtained. Benefits from the verification process included the ability to use coarser grids and insight into ways to reduce computational time by using double precision accuracy and non-integer grid ratios. Future valve modeling activities will include shape optimization of the valve/seat region and dynamic grid modeling.

  20. Dynamic analysis of a magnetic bearing system with flux control

    Science.gov (United States)

    Knight, Josiah; Walsh, Thomas; Virgin, Lawrence

    1994-01-01

    Using measured values of two-dimensional forces in a magnetic actuator, equations of motion for an active magnetic bearing are presented. The presence of geometric coupling between coordinate directions causes the equations of motion to be nonlinear. Two methods are used to examine the unbalance response of the system: simulation by direct integration in time; and determination of approximate steady state solutions by harmonic balance. For relatively large values of the derivative control coefficient, the system behaves in an essentially linear manner, but for lower values of this parameter, or for higher values of the coupling coefficient, the response shows a split of amplitudes in the two principal directions. This bifurcation is sensitive to initial conditions. The harmonic balance solution shows that the separation of amplitudes actually corresponds to a change in stability of multiple coexisting solutions.

  1. Remote controlled bio-stimulator and animal behavior analysis system

    Science.gov (United States)

    Song, Weiguo; Yuan, Kui; Han, Taizhen; Chai, Jie

    2006-01-01

    This paper presents a surveillance and stimulation system to study the animal locomotion behavior under electrical micro-stimulations in the brain nerve, which provides a new platform and methodology for behavior experiment in neural science. The system consists of two parts: 1) micro-control based multi-channel stimulator backed by animal; 2) Computer vision based animal behavior tracking system; The performance of the micro-stimulator is validated for sciatic nerve of frog and the results show that it is reliable, stabile, compact (25×35×10 mm), light (20g with cell). The tracking speed and accuracy is improved with our new hybrid tracking algorithm based on color table looking and moving predication, and compared with the manual recording. The preliminary results of rat tracking show that it works accurately and robustly in real-time even under interference condition.

  2. Universal Power Quality Controller Modeling and Inverters Loading Analysis

    Directory of Open Access Journals (Sweden)

    F. Gharedaghi

    2011-11-01

    Full Text Available As much as nonlinear loads and power electronics devices are more applied in power distribution systems, the importance of power quality increases. This study proposes a Universal Power Quality Conditioner (UPQC with double-converter structure. The operation principle, the algorithm of compensation reference generation, and the control method are introduced. Computer simulation and many prototype experiments are carried out to verify the operation principle and investigate the compensation characteristics of UPQC for different power quality problems. It is verified that the UPQC can effectively compensate multiple different power quality interferences originated either from the load side or from the line side. The capacity of series and shunt inverters is calculated through loading calculations of these inverters applying phasor diagram to increase the design accuracy. The results of simulation in MATLAB/SIMULINK software show that the system operates correctly.

  3. Control system analysis for the perturbed linear accelerator rf system

    CERN Document Server

    Sung Il Kwon

    2002-01-01

    This paper addresses the modeling problem of the linear accelerator RF system in SNS. Klystrons are modeled as linear parameter varying systems. The effect of the high voltage power supply ripple on the klystron output voltage and the output phase is modeled as an additive disturbance. The cavity is modeled as a linear system and the beam current is modeled as the exogenous disturbance. The output uncertainty of the low level RF system which results from the uncertainties in the RF components and cabling is modeled as multiplicative uncertainty. Also, the feedback loop uncertainty and digital signal processing signal conditioning subsystem uncertainties are lumped together and are modeled as multiplicative uncertainty. Finally, the time delays in the loop are modeled as a lumped time delay. For the perturbed open loop system, the closed loop system performance, and stability are analyzed with the PI feedback controller.

  4. Quality control analysis of seed of Dolichous biflorus Linn.

    Directory of Open Access Journals (Sweden)

    Wasim Ahmad

    2010-09-01

    Full Text Available Dolichous biflorus Linn. Popularly known as kulthi belongs to family fabaceae. It is also known by its medicinal properties, it is one of the most effective ayurvedic medicines for treating kidney stones. Its diuretic, anthelminthic properties make it an ideal drug for urinary and digestive disorders. Pharmacognistical standardization of Dolichous biflorus seed has been carried out in the present study. The study includes macroscopic evaluation along with estimation of its physicochemical parameters, preliminary phytochemical screening, estimation of total phenolics and flavonoids as well as fingerprint profile by HPTLC, HPLC and GCMS. Determinations of contaminants such as aflatoxins and pesticides also has been analysed and found no contaminants is present in the Dolichous biflorus seed sample. The quality control parameters in present study reveals standardization profile of Dolichous biflorus which would be of immense value in botanical identification and authentication of plant drug as well as may be helpful in preventing adulteration.

  5. Analysis of illegal peptide biopharmaceuticals frequently encountered by controlling agencies.

    Science.gov (United States)

    Vanhee, Celine; Janvier, Steven; Desmedt, Bart; Moens, Goedele; Deconinck, Eric; De Beer, Jacques O; Courselle, Patricia

    2015-09-01

    Recent advances in genomics, recombinant expression technologies and peptide synthesis have led to an increased development of protein and peptide therapeutics. Unfortunately this goes hand in hand with a growing market of counterfeit and illegal biopharmaceuticals, including substances that are still under pre-clinical and clinical development. These counterfeit and illegal protein and peptide substances could imply severe health threats as has been demonstrated by numerous case reports. The Belgian Federal Agency for Medicines and Health Products (FAMHP) and customs are striving, together with their global counterparts, to curtail the trafficking and distributions of these substances. At their request, suspected protein and peptide preparations are analysed in our Official Medicines Control Laboratory (OMCL). It stands to reason that a general screening method would be beneficiary in the battle against counterfeit and illegal peptide drugs. In this paper we present such general screening method employing liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the identification of counterfeit and illegal injectable peptide preparations, extended with a subsequent quantification method using ultra-high performance liquid chromatography with diode array detection (UHPLC-DAD). The screening method, taking only 30 min, is able to selectively detect 25 different peptides and incorporates the proposed minimum of five identification points (IP) as has been recommended for sports drug testing applications. The group of peptides represent substances which have already been detected in illegal and counterfeit products seized by different European countries as well as some biopharmaceutical peptides which have not been confiscated yet by the controlling agencies, but are already being used according to the many internet users forums. Additionally, we also show that when applying the same LC gradient, it is also possible to quantify these peptides without the need for

  6. Analysis of illegal peptide biopharmaceuticals frequently encountered by controlling agencies.

    Science.gov (United States)

    Vanhee, Celine; Janvier, Steven; Desmedt, Bart; Moens, Goedele; Deconinck, Eric; De Beer, Jacques O; Courselle, Patricia

    2015-09-01

    Recent advances in genomics, recombinant expression technologies and peptide synthesis have led to an increased development of protein and peptide therapeutics. Unfortunately this goes hand in hand with a growing market of counterfeit and illegal biopharmaceuticals, including substances that are still under pre-clinical and clinical development. These counterfeit and illegal protein and peptide substances could imply severe health threats as has been demonstrated by numerous case reports. The Belgian Federal Agency for Medicines and Health Products (FAMHP) and customs are striving, together with their global counterparts, to curtail the trafficking and distributions of these substances. At their request, suspected protein and peptide preparations are analysed in our Official Medicines Control Laboratory (OMCL). It stands to reason that a general screening method would be beneficiary in the battle against counterfeit and illegal peptide drugs. In this paper we present such general screening method employing liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the identification of counterfeit and illegal injectable peptide preparations, extended with a subsequent quantification method using ultra-high performance liquid chromatography with diode array detection (UHPLC-DAD). The screening method, taking only 30 min, is able to selectively detect 25 different peptides and incorporates the proposed minimum of five identification points (IP) as has been recommended for sports drug testing applications. The group of peptides represent substances which have already been detected in illegal and counterfeit products seized by different European countries as well as some biopharmaceutical peptides which have not been confiscated yet by the controlling agencies, but are already being used according to the many internet users forums. Additionally, we also show that when applying the same LC gradient, it is also possible to quantify these peptides without the need for

  7. Analysis methods for wind turbine control and electrical system dynamics

    Science.gov (United States)

    Hinrichsen, E. N.

    1995-01-01

    The integration of new energy technologies into electric power systems requires methods which recognize the full range of dynamic events in both the new generating unit and the power system. Since new energy technologies are initially perceived as small contributors to large systems, little attention is generally paid to system integration, i.e. dynamic events in the power system are ignored. As a result, most new energy sources are only capable of base-load operation, i.e. they have no load following or cycling capability. Wind turbines are no exception. Greater awareness of this implicit (and often unnecessary) limitation is needed. Analysis methods are recommended which include very low penetration (infinite bus) as well as very high penetration (stand-alone) scenarios.

  8. Modeling Illicit Drug Use Dynamics and Its Optimal Control Analysis

    Directory of Open Access Journals (Sweden)

    Steady Mushayabasa

    2015-01-01

    Full Text Available The global burden of death and disability attributable to illicit drug use, remains a significant threat to public health for both developed and developing nations. This paper presents a new mathematical modeling framework to investigate the effects of illicit drug use in the community. In our model the transmission process is captured as a social “contact” process between the susceptible individuals and illicit drug users. We conduct both epidemic and endemic analysis, with a focus on the threshold dynamics characterized by the basic reproduction number. Using our model, we present illustrative numerical results with a case study in Cape Town, Gauteng, Mpumalanga and Durban communities of South Africa. In addition, the basic model is extended to incorporate time dependent intervention strategies.

  9. Modeling Illicit Drug Use Dynamics and Its Optimal Control Analysis.

    Science.gov (United States)

    Mushayabasa, Steady; Tapedzesa, Gift

    2015-01-01

    The global burden of death and disability attributable to illicit drug use, remains a significant threat to public health for both developed and developing nations. This paper presents a new mathematical modeling framework to investigate the effects of illicit drug use in the community. In our model the transmission process is captured as a social "contact" process between the susceptible individuals and illicit drug users. We conduct both epidemic and endemic analysis, with a focus on the threshold dynamics characterized by the basic reproduction number. Using our model, we present illustrative numerical results with a case study in Cape Town, Gauteng, Mpumalanga and Durban communities of South Africa. In addition, the basic model is extended to incorporate time dependent intervention strategies. PMID:26819625

  10. High Performance Flow Analysis and Control Tools for Aerial Vehicles Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the project is to develop an open architecture, computer aided analysis and control design toolbox for distributed parameter systems, in...

  11. Bifurcation Tools for Flight Dynamics Analysis and Control System Design Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The purpose of the project is the development of a computational package for bifurcation analysis and advanced flight control of aircraft. The development of...

  12. Bifurcation Tools for Flight Dynamics Analysis and Control System Design Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Modern bifurcation analysis methods have been proposed for investigating flight dynamics and control system design in highly nonlinear regimes and also for the...

  13. Software requirements specification for the program analysis and control system risk management module

    Energy Technology Data Exchange (ETDEWEB)

    SCHAEFER, J.C.

    1999-06-02

    TWR Program Analysis and Control System Risk Module is used to facilitate specific data processes surrounding the Risk Management program of the Tank Waste Retrieval environment. This document contains the Risk Management system requirements of the database system.

  14. Software requirements specification for the program analysis and control system risk management module

    International Nuclear Information System (INIS)

    TWR Program Analysis and Control System Risk Module is used to facilitate specific data processes surrounding the Risk Management program of the Tank Waste Retrieval environment. This document contains the Risk Management system requirements of the database system

  15. Randomized Algorithms for Analysis and Control of Uncertain Systems With Applications

    CERN Document Server

    Tempo, Roberto; Dabbene, Fabrizio

    2013-01-01

    The presence of uncertainty in a system description has always been a critical issue in control. The main objective of Randomized Algorithms for Analysis and Control of Uncertain Systems, with Applications (Second Edition) is to introduce the reader to the fundamentals of probabilistic methods in the analysis and design of systems subject to deterministic and stochastic uncertainty. The approach propounded by this text guarantees a reduction in the computational complexity of classical  control algorithms and in the conservativeness of standard robust control techniques. The second edition has been thoroughly updated to reflect recent research and new applications with chapters on statistical learning theory, sequential methods for control and the scenario approach being completely rewritten.   Features: ·         self-contained treatment explaining Monte Carlo and Las Vegas randomized algorithms from their genesis in the principles of probability theory to their use for system analysis; ·    ...

  16. Design of Launch Vehicle Flight Control Systems Using Ascent Vehicle Stability Analysis Tool

    Science.gov (United States)

    Jang, Jiann-Woei; Alaniz, Abran; Hall, Robert; Bedossian, Nazareth; Hall, Charles; Jackson, Mark

    2011-01-01

    A launch vehicle represents a complicated flex-body structural environment for flight control system design. The Ascent-vehicle Stability Analysis Tool (ASAT) is developed to address the complicity in design and analysis of a launch vehicle. The design objective for the flight control system of a launch vehicle is to best follow guidance commands while robustly maintaining system stability. A constrained optimization approach takes the advantage of modern computational control techniques to simultaneously design multiple control systems in compliance with required design specs. "Tower Clearance" and "Load Relief" designs have been achieved for liftoff and max dynamic pressure flight regions, respectively, in the presence of large wind disturbances. The robustness of the flight control system designs has been verified in the frequency domain Monte Carlo analysis using ASAT.

  17. Fuzzy control systems with time-delay and stochastic perturbation analysis and synthesis

    CERN Document Server

    Wu, Ligang; Shi, Peng

    2015-01-01

    This book presents up-to-date research developments and novel methodologies on fuzzy control systems. It presents solutions to a series of problems with new approaches for the analysis and synthesis of fuzzy time-delay systems and fuzzy stochastic systems, including stability analysis and stabilization, dynamic output feedback control, robust filter design, and model approximation. A set of newly developed techniques such as fuzzy Lyapunov function approach, delay-partitioning, reciprocally convex, cone complementary linearization approach are presented. Fuzzy Control Systems with Time-Delay and Stochastic Perturbation: Analysis and Synthesis is a comprehensive reference for researcher and practitioners working in control engineering, system sciences and applied mathematics, and is also a useful source of information for senior undergraduates and graduates in these areas. The readers will benefit from some new concepts, new models and new methodologies with practical significance in control engineering and si...

  18. Reliability analysis of the control system of large-scale vertical mixing equipment

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The control system of vertical mixing equipment is a concentrate distributed monitoring system (CDMS).A reliability analysis model was built and its analysis was conducted based on reliability modeling theories such as the graph theory,Markov process,and redundancy theory.Analysis and operational results show that the control system can meet all technical requirements for high energy composite solid propellant manufacturing.The reliability performance of the control system can be considerably improved by adopting a control strategy combined with the hot spared redundancy of the primary system and the cold spared redundancy of the emergent one.The reliability performance of the control system can be also improved by adopting the redundancy strategy or improving the quality of each component and cable of the system.

  19. Comparison of nested case-control and survival analysis methodologies for analysis of time-dependent exposure

    Directory of Open Access Journals (Sweden)

    Platt Robert W

    2005-01-01

    Full Text Available Abstract Background Epidemiological studies of exposures that vary with time require an additional level of methodological complexity to account for the time-dependence of exposure. This study compares a nested case-control approach for the study of time-dependent exposure with cohort analysis using Cox regression including time-dependent covariates. Methods A cohort of 1340 subjects with four fixed and seven time-dependent covariates was used for this study. Nested case-control analyses were repeated 100 times for each of 4, 8, 16, 32, and 64 controls per case, and point estimates were compared to those obtained using Cox regression on the full cohort. Computational efficiencies were evaluated by comparing central processing unit times required for analysis of the cohort at sizes 1, 2, 4, 8, 16, and 32 times its initial size. Results Nested case-control analyses yielded results that were similar to results of Cox regression on the full cohort. Cox regression was found to be 125 times slower than the nested case-control approach (using four controls per case. Conclusions The nested case-control approach is a useful alternative for cohort analysis when studying time-dependent exposures. Its superior computational efficiency may be particularly useful when studying rare outcomes in databases, where the ability to analyze larger sample sizes can improve the power of the study.

  20. Electromagnetic analysis of locking device for SMART control element drive mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Huh, Hyung; Kim, J. I.; Kim, J. H. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1998-09-01

    A numerical electromagnetic analysis was performed for the control rod locking device which is installed in the control element drive mechanism of integral reactor, SMART. A plunger model for the electromagnetic analysis of the locking device was developed and theoretical bases for the model were established. Design parameters related to plunger pushing force were identified, and the optimum design point was determined by analysing the trend of the plunger pushing force with finite element method. 8 refs., 22 figs., 2 tabs. (Author)

  1. In vivo modular control analysis of energy metabolism in contracting skeletal muscle

    OpenAIRE

    Arsac, Laurent M; Beuste, Christophe; Miraux, Sylvain; Deschodt-Arsac, Veronique; Thiaudière, Eric; Franconi, Jean-Michel; Diolez, Philippe H

    2008-01-01

    Abstract We used 31P MR spectroscopy measurements of energetic intermediates (ATP, Pi, PCr) in combination with the analytical tools of metabolic control analysis to study in vivo energy metabolism in contracting skeletal muscle of anesthetized rats over a broad range of workload. According to our recent Modular Control Analysis (MoCA) used to describe regulatory mechanisms in beating heart, we defined the energetic system of muscle contraction as two modules (PCr-Producer and PCr-...

  2. Analysis of Trap-controlled Conduction in Modified PTFE

    Institute of Scientific and Technical Information of China (English)

    WU Jiang; WANG Jin-feng; SHEN Bin; ZHENG Xiao-quan

    2011-01-01

    The reasonable conduction property is beneficial to release the deposited charges by conduction current in di- electric space charging environment, thus the level of the deep charging and the pulse discharge can effectively be weakened and inhibited. A traditional method for conductivity measuring under ground circumstance was used, and both the applied voltage and temperature were varied to determine the dependence of volume conductivity in PTFE modified by different filler contents. The results inferred the volume conductivity was significantly affected by the phenomenon of the percolation conduction, as well as the high-field conduction. The shallow and deep charge traps were considered to be a key factor in volume conductivity variation. In this theory, modified by inorganic semi conductive filler, the distribution of trap density and depth in PTFE can be controlled to achieve the ideal temperature dependent conduction property and high-field conduction property, which will finally lead to gentle release of the deposi ted charges while the electrostatic field reaches the conductivity-variation threshold.

  3. Scenario analysis of false indication in computer-control systems

    International Nuclear Information System (INIS)

    Highlights: ► A new failure mode and effect for safety-critical systems is proposed. ► False indication is the most dreadful kind of partial failures. ► A model-based simulation approach to generate failure scenarios is proposed. ► Simulation results showed that multiple errors may cause undesired consequences. ► An assertion-based method to detect false indication problems is provided. -- Abstract: Computer control may cause additional failure modes and effects that are new to analogue systems. False indication is one such failure mode that may bring unknown risks to a system. False indication refers to the problem when part of a system fails while other processes still work, and the failure is not revealed to operators. This paper presents a model-based simulation approach to systematically generate potential false indication and unintended consequences. Experiments showed that once a false indication occurs, it may have drastic effects on system safety. False indication can mislead the operator to perform adverse actions or no action. Therefore, we propose an assertion-based detection method to alleviate such failures. Our assertions contain process/device dependencies, timing relations and physical conservation rules. With these assertions, the operator may be alerted at run time. The proposed technique can reduce false indication problem. Moreover, it can also be used to assist the system design.

  4. Performance Analysis of Novel Overload Control with Threshold Mechanism

    Directory of Open Access Journals (Sweden)

    Doo Il Choi

    2016-01-01

    Full Text Available We propose a novel overload control method with hysteresis property; that is, we analyze the M/G/1/K queueing system where the service and arrival rates are varied depending on the queue-length. We use two threshold values: L1(≤L2 and L2(≤K. When the queue-length increases by an amount between L1 and L2, we apply one of the following two strategies to reduce the queue-length, either we decrease the mean service time or we decrease the arrival rate. If the queue-length exceeds L2 with one strategy, we apply the other; thus, there are two models that depend on the method that was applied first. We derive the queue-length distribution at departure and at arbitrary epochs using the embedded Markov chain method and the supplementary variable method. We investigate performance measures including the loss probability and mean waiting time using various numerical examples.

  5. COMPARATIVE ANALYSIS OF CONGESTION CONTROL MODELS FOR CELLULAR WIRELESS NETWORK

    Directory of Open Access Journals (Sweden)

    Falade A. J

    2015-08-01

    Full Text Available Cellular wireless systems like GSM suffer from congestion resulting in overall system degradation and poor service delivery. When the traffic demand in a geographical area is high, the input traffic rate will exceed thecapacity of the output lines. This work focused on homogenous wireless network (the network traffic and resource dimensioning that are statistically identical such that the network performance evaluation can be reduced to a system with single cell and a single traffic type. Such system can employa queuing model to evaluate the performance metric of a cell in terms of blocking probability. Five congestion control models were compared in the work to ascertain their peculiarities, they are Erlang B, Erlang C, Engset (cleared, Engset (buffered, and Bernoulli. To analyze the system, an aggregate onedimensional Markov chain wasderived, such that it describes a call arrival process under the assumption that it is Poisson distributed. The models were simulated and their results show varying performances, however the Bernoulli model (Pb5 tends to show a situation that allows more users access to the system and the congestion level remain unaffected despite increase in the number of users and the offered traffic into the system.

  6. Nonlinear Magnetic Circuit Analysis of SMART Control Rod Drive Actuator

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Myounggyu; Gi, Myung Ju; Kim, Myounggon; Park, Youngwoo [Chungnam Nat' l Univ., Daejeon (Korea, Republic of); Lee, Jaeseon; Kim, Jongwook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    In this paper, we derive a nonlinear magnetic circuit model of an electromagnetic control-rod actuator in the SMART. The results of the nonlinear model are compared with those by linear circuit model and finite-element analyses. gnetic circuit modeling is a useful tool when designing an electromagnetic actuator, as it allows fast calculations and enables parametric studies. It is particularly essential when the actuator is to be used in a very complex system such as a nuclear reactor. Important design parameters must be identified at the early stage of the design process. Once the design space is narrowed down, more accurate methods such finite-element analyses (FEA) can be employed for detailed design. Magnetic circuit modeling is based on the assumption that a flux path consists of sections in each of which field quantities are constant with linear constitutive relations. This assumption fails to hold when portions of the flux path become saturated. The magnetic circuit must be modified in order to accurately describe the nonlinear behavior of saturation.

  7. Integrated Evaluation of Air Traffic Controller Workload Based on Matter-Element Analysis

    Institute of Scientific and Technical Information of China (English)

    ZHANG Ming; HAN Song-chen

    2008-01-01

    A model for evaluating the controller workload was presented based on matter-element analysis, particularly from a man-machine-environment system engineering perspective. On the basis of a questionnaire survey, 18 kinds of indexes which influence the controller workload were determined. By establishing the classical field and node field of the controller workload, the correlation function of the controller workload grade was obtained; then the correlation degree and estimated grade of controller workload were given. A case study verifies the feasibility of the proposed evaluation method.

  8. Experimental analysis on adjusting performance of vapor-liquid two-phase flow controller

    Institute of Scientific and Technical Information of China (English)

    LI Hui-jun; TU Shan

    2006-01-01

    The vapor-liquid self-adjusting controller is an innovative automatic regulating valve. In order to ensure adjusted objects run safely and economically, the controller automatically adjusts the liquid flux to keep liquid level at a required level according to physical properties of vapor-liquid two-phase fluid. The adjusting mechanics, the controller' s performance and influencing factors of its stability have been analyzed in this paper. The theoretical analysis and successful applications have demonstrated this controller can keep the liquid level steady with good performance. The actual application in industry has shown that the controller can satisfactorily meet the requirement of industrial production and has wide application areas.

  9. The role of function analysis in the ACR control centre design

    International Nuclear Information System (INIS)

    An essential aspect of control centre design is the need to characterize: plant functions and their inter-relationships to support the achievement of operational goals, and roles for humans and automation in sharing and exchanging the execution of functions across all operational phases. Function analysis is a design activity that has been internationally accepted as an approach to satisfy this need. It is recognized as a fundamental and necessary component in the systematic approach to control centre design and is carried out early in the design process. A function analysis can provide a clear basis for: the control centre design for the purposes of design team communication, and customer or regulatory review, the control centre display and control systems, the staffing and layout requirements of the control centre, assessing the completeness of control centre displays and controls prior and supplementary to mock-up walkthroughs or simulator evaluations, and the design of operating procedures and training programs. This paper will explore the role for function analysis in supporting the design of the control centre. The development of the ACR control room will be used as an illustrative context for the discussion. The paper will also discuss the merits of using function analysis in a goal-or function-based approach resulting in a more robust, operationally compatible, and cost-effective design over the life of the plant. Two former papers have previously outlined, the evolution in AECL's application approach and lessons learned in applying function analysis in support of control room design. This paper provides the most recent update to this progression in application refinement. (author)

  10. Top-down control analysis of systems with more than one common intermediate.

    Science.gov (United States)

    Ainscow, E K; Brand, M D

    1995-08-01

    The analysis of the control of complex metabolic systems can be greatly simplified by application of the top-down approach of metabolic control analysis, in which the reactions of the system are grouped together into a small number of blocks connected by a common intermediate. The experimental application of the top-down approach has so far been limited to systems that have only a single intermediate. In this study, we demonstrate that the connectivity and summation theorems of metabolic control analysis hold with any number of intermediates between the metabolic blocks, and in doing so show that top-down analysis is valid for systems with multiple intermediates and so can be applied to most metabolic systems regardless of their complexity; an example of such an application is provided. Top-down control analysis has successfully described the control of mitochondrial respiration by dividing the system into three blocks, the respiratory chain, phosphorylation system and proton leak, all linked by a single intermediate, proton motive force. Here, we subdivide the respiratory chain into succinate consumers and cytochrome oxidase so that a second intermediate, cytochrome c redox state, is generated. Despite the fact that the redox state of cytochrome c is not measured, we solve the control over the system fluxes. In common with previous studies, we find that under conditions where there is no ATP turnover (state 4), respiration is largely controlled by proton leak, while at maximal ATP turnover (state 3) respiration is controlled by the respiratory chain and the phosphorylating system. In state 4,85% of the control by the respiratory chain resides with cytochrome oxidase. As ATP turnover increases, the respiration rate increases, and the control by the respiratory chain shifts from cytochrome oxidase to the succinate consumers, so that in state 3 83% of the control by the respiratory chain lies in the reactions between succinate and cytochrome c and only 17% resides

  11. The Control System Modeling and The Mechanical Structure Analysis For EMCVT

    Directory of Open Access Journals (Sweden)

    Lei ZHANG

    2013-07-01

    Full Text Available The current automotive metallic belt continuously variable transmission (CVT mostly use hydraulic system to push the cone disc and achieve the speed ratio control. A new Electrical Mechanical Continuously Variable Transmission without hydraulic control (Electrical Mechanical CVT, EMCVT studied in this paper, uses the rolling screw mechanism to press cone disc, achieves speed regulation through the electronic control mechanism, and abandons the energy-intensive hydraulic system. In this paper, based on the analysis of mechanical configuration, the EMCVT's transmission system and its speed regulation process, speed ratio control characteristic and the clamping force control feature are studied and modeled. Besides, the Control strategy of the transmission system driven by motor is built, so as to provide an important theoretical basis for the further building of EMVCT's control system and the selection and implementation of Control strategy.

  12. [Analysis suspected allergic factors to shenqi fuzheng injection based on prescription sequence analysis and nested case control study].

    Science.gov (United States)

    Ai, Qing-Hua; Zeng, Xian-Bin; Xie, Yan-Ming; Yang, Wei

    2014-09-01

    This study based on twenty 3A grade hospital information system (HIS) database in China, adopt toprescription sequence analysis (PSA) with nested case control study (NCCS) to analysis mainly suspected allergy factor of Shenqi Fuzheng injection (Shenqi Fuzheng). Study design according to start to stop using Shenqi Fuzheng whether using dexamethasone injection will crowd divided into cases group and control group, each case matched 4 controls were selected, two groups according to the ratio of the age and sex matched well. Square test, Fisher exact test, single factor and multiple factor logistic regression were used to analyze data Condition on admission, allergic history, dosage and drug combinations were taken into account in cases of suspected allergic reactions. After analysis in two subgroups we found that the single dose (P = 0.000 2) and the combined use of matrine (P marketing Chinese medicine injection. PMID:25532396

  13. Analysis of power and frequency control requirements in view of increased decentralized production and market liberalization

    NARCIS (Netherlands)

    Roffel, Brian; Boer, de Wouter W.

    2003-01-01

    This paper presents a systematic approach of the analysis of the minimum control requirements that are imposed on power producing units in the Netherlands, especially in the case when decentralized production increases. Also some effects of the liberalization on the control behavior are analyzed. Fi

  14. Effects of Joint Controller on Analytical Modal Analysis of Rotational Flexible Manipulator

    Institute of Scientific and Technical Information of China (English)

    CHU Ming; ZHANG Yanheng; CHEN Gang; SUN Hanxu

    2015-01-01

    Modal analysis is a fundamental and important task for modeling and control of the flexible manipulator. However, almost all of the traditional modal analysis methods view the flexible manipulator as a pure mechanical structure and neglect feedback action of joint controller. In order to study the effects of joint controller on the modal analysis of rotational flexible manipulator, a closed-loop analytical modal analysis method is proposed. Firstly, two exact boundary constralnts, namely servo feedback constralnt and bending moment constralnt, are derived to solve the vibration partial differential equation. It is found that the stiffness and damping galns of joint controller are both included in the boundary conditions, which lead to an unconventional secular term. Secondly, analytical algorithm based on Ritz approach is developed by using Laplace transform and complex modal approach to obtaln the natural frequencies and mode shapes. And then, the numerical simulations are performed and the computational results show that joint controller has pronounced influence on the modal parameters:joint controller stiffness reduces the natural frequency, while joint controller damping makes the shape phase non-zero. Furthermore, the validity of the presented conclusion is confirmed through experimental studies. These findings are expected to improve the performance of dynamics simulation systems and model-based controllers.

  15. Discretization behavior analysis of a switching control system from a unified mathematical approach

    Institute of Scientific and Technical Information of China (English)

    Xinghuo YU; Ling YANG; Guanrong CHEN

    2003-01-01

    A useful unified analysis framework is proposed for exploring the intriguing behaviors of a second-order switching control system. Complex discretization behaviors of the switching control system are explored in detail, and some intrinsic relationships between the system periodic behaviors and their associated symbolic sequences are studied.

  16. Performance analysis of multichannel medium access control algorithms for opportunistic spectrum access

    NARCIS (Netherlands)

    Pawelczak, P.; Pollin, S.; So, H.-S.W.; Bahai, A.R.S.; Prasad, R.V.; Hekmat, R.

    2009-01-01

    In this paper, different control channel (CC) implementations for multichannel medium access control (MAC) algorithms are compared and analyzed in the context of opportunistic spectrum access (OSA) as a function of spectrum-sensing performance and licensed user activity. The analysis is based on a d

  17. Comparative analysis of tertiary control systems for smart grids using the Flex Street model

    NARCIS (Netherlands)

    Claessen, F.N.; Claessens, B.; Hommelberg, M.P.F.; Molderink, A.; Bakker, V.; Toersche, H.A.; van den Broek, M.A.

    2014-01-01

    Various smart grid control systems have been developed with different architectures. Comparison helps developers identify their strong and weak points. A three-step analysis method is proposed to facilitate the comparison of independently developed control systems. In the first step, a microgrid mod

  18. On the analysis of lead-time disturbances in production and inventory control models

    OpenAIRE

    Spiegler, VLM; Naim, MM; Syntetos, A

    2015-01-01

    Changes in the lead-time can lead to supply chain inefficiencies and risks. In this paper, we investigate the effects of lead-time disturbances on the system’s output responses of a production and inventory control model. In the adaption process of the control system for lead-time disturbance analysis, the resulting model becomes nonlinear. Hence nonlinear control theory in combination with simulation is used to analyse the impact of leadtime changes on the transient and steady state respo...

  19. Stability Analysis of Nonlinear Feedback Control Methods for Beam Halo-chaos

    Institute of Scientific and Technical Information of China (English)

    WANGZhong-sheng; FANGJin-qing; CHENGuan-rong

    2003-01-01

    Control of beam halo-chaos has been a more challenge subject in recent years, in which nonlinear feedback method for beam halo-chaos has been developed for control of beam halo-chaos in high-current proton linear accelerators. However, stability analysis of nonlinear feedback control methods for beam halo-chaos has still been an open and important topic in this field. In this letter.

  20. Analysis of Unconstrained Nonlinear MPC Schemes with Time Varying Control Horizons

    CERN Document Server

    Grüne, Lars; Seehafer, Martin; Worthmann, Karl

    2012-01-01

    For nonlinear discrete time systems satisfying a controllability condition, we present a stability condition for model predictive control without stabilizing terminal constraints or costs. The condition is given in terms of an analytical formula which can be employed in order to determine a prediction horizon length for which asymptotic stability or a performance guarantee is ensured. Based on this formula a sensitivity analysis with respect to the prediction and the possibly time varying control horizon is carried out.

  1. Structural analysis and design of multivariable control systems: An algebraic approach

    Science.gov (United States)

    Tsay, Yih Tsong; Shieh, Leang-San; Barnett, Stephen

    1988-01-01

    The application of algebraic system theory to the design of controllers for multivariable (MV) systems is explored analytically using an approach based on state-space representations and matrix-fraction descriptions. Chapters are devoted to characteristic lambda matrices and canonical descriptions of MIMO systems; spectral analysis, divisors, and spectral factors of nonsingular lambda matrices; feedback control of MV systems; and structural decomposition theories and their application to MV control systems.

  2. ANALYSIS OF LEPTOBARBUS HOEVENII IN CONTROL ENVIRONMENT AT NATURAL LAKES

    Directory of Open Access Journals (Sweden)

    Mohd Khairul Amri Kamarudin

    2013-01-01

    Full Text Available Leptobarbus hoevenii or its common name Ikan Jelawat is a high-value fish from family Cyprinidae, genus Leptobarbus are omnivorous fish that can grow up to 60 cm long. Due to human activities and the time change, this species has been depleted in Lake Chini. As an initiative from the Malaysian government, a conservation project for this species has been carried out. This article discussed the results on growth-up monitoring of L. hoevenii on the food and environment factor in conservation cage at Lake Chini. Monitoring of the grown-up, food and water quality of chemical composition was carried out for four months of this study. The results of statistical analysis showed, L. hoevenii growth is a positive rate with the Body Weight (BW and Total Length (TL on R2 0.986 and R2 0.988 respectively, by using floating type ‘grower pellet’, with 32% of protein. However, the Jemberau River basin is experiencing changes due logging and mining activities and that have affected to the chemical composition of the water quality and environmental. The iron content in the first week is ±0.0 mg L-1 change to ±5.0 mg L-1 and ±0.0 mg L-1 to ±2.0 mg L-1 for ammonia content in 10 weeks. The high content of the iron and ammonia on the water quality in the cage areas, effected for livestock to be stressed and also to the diet and growth-up of fish. 2500 of batch 1 L. hoevenii that has been released in Lake Chini showed they can be adapted to the local environment at the Laut Jemberau Lake, but take a time. Therefore, the closure of the Laut Jemberau Lake as fish conservation area is proposed to ensure that conservation objectives are achieved.

  3. A pooled analysis of case-control studies of thyroid cancer - I. Methods

    NARCIS (Netherlands)

    Negri, E; Ron, E; Franceschi, S; Dal Maso, L; Mark, SD; Preston-Martin, S; McTiernan, A; Kolonel, L; Kleinerman, R; Land, C; Jin, F; Wingren, G; Galanti, MR; Hallquist, A; Glattre, E; Lund, E; Levi, F; Linos, D; Braga, C; La Vecchia, C

    1999-01-01

    Objective. Because the etiology of thyroid cancer is not well described, we conducted a pooled analysis of all published case-control studies, as well as two identified unpublished studies. This paper describes the major characteristics of the 14 studies included in the analysis, as well as the stat

  4. 21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.

    Science.gov (United States)

    2010-04-01

    ...) plan. 120.8 Section 120.8 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS... processor shall have and implement a written HACCP plan whenever a hazard analysis reveals one or more...

  5. Transient stability and control of renewable generators based on Hamiltonian surface shaping and power flow control. Part II, analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Robinett, Rush D., III; Wilson, David Gerald

    2010-11-01

    The swing equations for renewable generators connected to the grid are developed and a wind turbine is used as an example. The swing equations for the renewable generators are formulated as a natural Hamiltonian system with externally applied non-conservative forces. A two-step process referred to as Hamiltonian Surface Shaping and Power Flow Control (HSSPFC) is used to analyze and design feedback controllers for the renewable generators system. This formulation extends previous results on the analytical verification of the Potential Energy Boundary Surface (PEBS) method to nonlinear control analysis and design and justifies the decomposition of the system into conservative and non-conservative systems to enable a two-step, serial analysis and design procedure. The first step is to analyze the system as a conservative natural Hamiltonian system with no externally applied non-conservative forces. The Hamiltonian surface of the swing equations is related to the Equal-Area Criterion and the PEBS method to formulate the nonlinear transient stability problem. This formulation demonstrates the effectiveness of proportional feedback control to expand the stability region. The second step is to analyze the system as natural Hamiltonian system with externally applied non-conservative forces. The time derivative of the Hamiltonian produces the work/rate (power flow) equation which is used to ensure balanced power flows from the renewable generators to the loads. The Second Law of Thermodynamics is applied to the power flow equations to determine the stability boundaries (limit cycles) of the renewable generators system and enable design of feedback controllers that meet stability requirements while maximizing the power generation and flow to the load. Necessary and sufficient conditions for stability of renewable generators systems are determined based on the concepts of Hamiltonian systems, power flow, exergy (the maximum work that can be extracted from an energy flow) rate

  6. Advanced electric drives analysis, control, and modeling using MATLAB/Simulink

    CERN Document Server

    Mohan, Ned

    2014-01-01

    Advanced Electric Drives utilizes a physics-based approach to explain the fundamental concepts of modern electric drive control and its operation under dynamic conditions. Gives readers a "physical" picture of electric machines and drives without resorting to mathematical transformations for easy visualization Confirms the physics-based analysis of electric drives mathematically Provides readers with an analysis of electric machines in a way that can be easily interfaced to common power electronic converters and controlled using any control scheme Makes the MATLAB/Simulink files used in exampl

  7. Attitude Analysis and Robust Adaptive Backstepping Sliding Mode Control of Spacecrafts Orbiting Irregular Asteroids

    Directory of Open Access Journals (Sweden)

    Chunhui Liang

    2014-01-01

    Full Text Available Attitude stability analysis and robust control algorithms for spacecrafts orbiting irregular asteroids are investigated in the presence of model uncertainties and external disturbances. Rigid spacecraft nonlinear attitude models are considered and detailed attitude stability analysis of spacecraft subjected to the gravity gradient torque in an irregular central gravity field is included in retrograde orbits and direct orbits using linearized system model. The robust adaptive backstepping sliding mode control laws are designed to make the attitude of the spacecrafts stabilized and responded accurately to the expectation in the presence of disturbances and parametric uncertainties. Numerical simulations are included to illustrate the spacecraft performance obtained using the proposed control laws.

  8. Adaptive randomized algorithms for analysis and design of control systems under uncertain environments

    Science.gov (United States)

    Chen, Xinjia

    2015-05-01

    We consider the general problem of analysis and design of control systems in the presence of uncertainties. We treat uncertainties that affect a control system as random variables. The performance of the system is measured by the expectation of some derived random variables, which are typically bounded. We develop adaptive sequential randomized algorithms for estimating and optimizing the expectation of such bounded random variables with guaranteed accuracy and confidence level. These algorithms can be applied to overcome the conservatism and computational complexity in the analysis and design of controllers to be used in uncertain environments. We develop methods for investigating the optimality and computational complexity of such algorithms.

  9. Predictive Analysis of Geochemical Controls in an Alpine Stream

    Science.gov (United States)

    Jochems, A. P.; Sherson, L. R.; Crossey, L. J.; Karlstrom, K. E.

    2010-12-01

    Alpine watersheds are increasingly relied upon for use in the American West, necessitating a more complete understanding of annual hydrologic patterns and geologic influences on water chemistry. The Jemez River is a fifth order stream in central New Mexico that flows from its source in the Jemez Mountains to its confluence with the Rio Grande north of the town of Bernalillo. Designated uses of the Jemez River include domestic water supply, recreation, and agriculture. Geothermal uses are currently being considered as well. The river recharges shallow aquifer waters used by several communities, including tribal lands of the Jemez Pueblo. The hydrogeology of the Jemez system is characterized by geothermal inputs from the Baca hydrothermal system associated with the 1.2Ma Valles caldera, as well as groundwater and surface water interactions. Freshwater input from the Rio Guadalupe and several ephemeral tributaries also influences the water chemistry of the Jemez system. Fifteen sites along a 35 km reach of the river were sampled between 2006 and 2010. Discharge of the Jemez River ranged from 10-876 cfs over the study period. The annual hydrograph is affected by annual snowmelt in the Jemez Mountains as well as surges due to monsoonal rains in July and August. Geochemical data collected over this period include temperature, conductivity, pH, dissolved oxygen (D.O.), major ions, trace elements, and stable isotopes. Continuous records of temperature, conductivity, pH, D.O. and turbidity data were collected from a water quality sonde installed in March 2010. Geochemical modeling and time series analysis were performed using PHREEQC, Geochemist’s Workbench, and MATLAB. Empirical data collected during this study gave rise to several models describing the hydrology and geochemistry of the Jemez system. Our data suggest that springs are the primary contributors to dissolved load, and that solute loading from geothermal inputs is intensified by low flows observed on

  10. Stability and performance analysis of a jump linear control system subject to digital upsets

    Institute of Scientific and Technical Information of China (English)

    王蕊; 孙辉; 马振洋

    2015-01-01

    This paper focuses on the methodology analysis for the stability and the corresponding tracking performance of a closed-loop digital jump linear control system with a stochastic switching signal. The method is applied to a flight control system. A distributed recoverable platform is implemented on the flight control system and subject to independent digital upsets. The upset processes are used to stimulate electromagnetic environments. Specifically, the paper presents the scenarios that the upset process is directly injected into the distributed flight control system, which is modeled by independent Markov upset processes and independent and identically distributed (IID) processes. A theoretical performance analysis and simulation modelling are both presented in detail for a more complete independent digital upset injection. The specific examples are proposed to verify the methodology of tracking performance analysis. The general analyses for different configurations are also proposed. Comparisons among different configurations are conducted to demonstrate the availability and the characteristics of the design.

  11. An improved, computer-based, on-line gamma monitor for plutonium anion exchange process control

    International Nuclear Information System (INIS)

    An improved, low-cost, computer-based system has replaced a previously developed on-line gamma monitor. Both instruments continuously profile uranium, plutonium, and americium in the nitrate anion exchange process used to recover and purify plutonium at the Los Alamos Plutonium Facility. The latest system incorporates a personal computer that provides full-feature multichannel analyzer (MCA) capabilities by means of a single-slot, plug-in integrated circuit board. In addition to controlling all MCA functions, the computer program continuously corrects for gain shift and performs all other data processing functions. This Plutonium Recovery Operations Gamma Ray Energy Spectrometer System (PROGRESS) provides on-line process operational data essential for efficient operation. By identifying abnormal conditions in real time, it allows operators to take corrective actions promptly. The decision-making capability of the computer will be of increasing value as we implement automated process-control functions in the future. 4 refs., 6 figs

  12. CONTROL AND STABILITY ANALYSIS OF THE GMC ALGORITHM APPLIED TO pH SYSTEMS

    Directory of Open Access Journals (Sweden)

    Manzi J.T.

    1998-01-01

    Full Text Available This paper deals with the control of the neutralization processes of the strong acid-strong base and the weak acid-strong base systems using the Generic Model Control (GMC algorithm. The control strategy is applied to a pilot plant where hydrochloric acid-sodium hydroxide and acetic acid-sodium hydroxide systems are neutralized. The GMC algorithm includes in the controller structure a nonlinear model of the process in the controller structure. The paper also focuses the provides a stability analysis of the controller for some of the uncertainties involved in the system. The rResults indicate that the controller stabilizes the system for a large range of uncertainties, but the performance may deteriorate when the system is submitted to large disturbances.

  13. Design and analysis of an intelligent controller for active geometry suspension systems

    Science.gov (United States)

    Goodarzi, Avesta; Oloomi, Ehsan; Esmailzadeh, Ebrahim

    2011-02-01

    An active geometry suspension (AGS) system is a device to optimise suspension-related factors such as toe angle and roll centre height by controlling vehicle's suspension geometry. The suspension geometry could be changed through control of suspension mounting point's position. In this paper, analysis and control of an AGS system is addressed. First, the effects of suspension geometry change on roll centre height and toe angle are studied. Then, based on an analytical approach, the improvement of the vehicle's stability and handling due to the control of suspension geometry is investigated. In the next section, an eight-degree-of-freedom handling model of a sport utility vehicle equipped with an AGS system is introduced. Finally, a self-tuning proportional-integral controller has been designed, using the fuzzy control theory, to control the actuator that changes the geometry of the suspension system. The simulation results show that an AGS system can improve the handling and stability of the vehicle.

  14. Radial basis function (RBF) neural network control for mechanical systems design, analysis and Matlab simulation

    CERN Document Server

    Liu, Jinkun

    2013-01-01

    Radial Basis Function (RBF) Neural Network Control for Mechanical Systems is motivated by the need for systematic design approaches to stable adaptive control system design using neural network approximation-based techniques. The main objectives of the book are to introduce the concrete design methods and MATLAB simulation of stable adaptive RBF neural control strategies. In this book, a broad range of implementable neural network control design methods for mechanical systems are presented, such as robot manipulators, inverted pendulums, single link flexible joint robots, motors, etc. Advanced neural network controller design methods and their stability analysis are explored. The book provides readers with the fundamentals of neural network control system design.   This book is intended for the researchers in the fields of neural adaptive control, mechanical systems, Matlab simulation, engineering design, robotics and automation. Jinkun Liu is a professor at Beijing University of Aeronautics and Astronauti...

  15. Control Volume Analysis, Entropy Balance and the Entropy Production in Flow Systems

    CERN Document Server

    Niven, Robert K

    2014-01-01

    This chapter concerns "control volume analysis", the standard engineering tool for the analysis of flow systems, and its application to entropy balance calculations. Firstly, the principles of control volume analysis are enunciated and applied to flows of conserved quantities (e.g. mass, momentum, energy) through a control volume, giving integral (Reynolds transport theorem) and differential forms of the conservation equations. Several definitions of steady state are discussed. The concept of "entropy" is then established using Jaynes' maximum entropy method, both in general and in equilibrium thermodynamics. The thermodynamic entropy then gives the "entropy production" concept. Equations for the entropy production are then derived for simple, integral and infinitesimal flow systems. Some technical aspects are examined, including discrete and continuum representations of volume elements, the effect of radiation, and the analysis of systems subdivided into compartments. A Reynolds decomposition of the entropy ...

  16. Influence of synthetic temperature and heating time on the luminescence behavior of M5(PO4)3Cl:Eu2+,Mn2+(M=Ca, Sr) phosphors

    Institute of Scientific and Technical Information of China (English)

    杨凤丽; 安炜; 李宏彦; HU Yunsheng; 胡运生; 徐会兵; 叶信宇; 庄卫东; 荆西平

    2015-01-01

    To further understand the energy loss mechanism of the“charge transfer process”that was proposed in our previous work on Eu2+-Mn2+co-doped phosphors, the influence of synthetic temperature and heating time on the photoluminescence (PL) behavior of M5(PO4)3Cl:Eu2+,Mn2+(M=Ca, Sr) phosphors was investigated by analyzing their PL spectra and decay curves. For the Ca phase, an increase in the synthetic temperature resulted in an increase in the loss from the“charge transfer process”since more Eu2+ions were involved in the Eu2+-Mn2+clusters. This was contrary to the thermodynamic expectation. To solve this contradiction, we pro-posed that the formation of Eu2+-Mn2+clusters was kinetically blocked at lower synthetic temperatures. With an increase in heating time for the phosphors synthesized at lower temperature (such as 1100 °C) the PL intensity decreased, which supported the above as-sertion.

  17. Hydrothermal synthesis and luminescent properties of color-tunable Dy3+ doped and Eu3+/Tb3+ co-doped MMoO4 (M=Ca, Sr, Ba) phosphors

    International Nuclear Information System (INIS)

    Dy3+ doped and Eu3+/Tb3+ co-doped MMoO4 (M=Ca, Sr, Ba) phosphors have been successfully prepared via a simple surfactant-free hydrothermal method. Their crystal structure, morphology, and luminescent characteristics were investigated. The results show that the as-prepared CaMoO4 particles have the cylinder-like shape, SrMoO4 samples present dumbbell-like shape, and the as-prepared BaMoO4 products show micro-rods shape with a length of 5–15 μm. MMoO4:Dy3+ phosphors exhibited the characteristic excitation and emission transitions of Dy3+ and most of the chromaticity coordinates are located in the white-light region. In addition, with increasing Dy3+ ions concentration the color changes gradually from near blue to near yellow. All the characteristic emissions of Eu3+ and Tb3+ can be observed in Eu3+/Tb3+ co-doped MMoO4 phosphors, and the emission color can be easily tuned from red, through yellow or green-yellow, to green by simply adjusting the relative doping concentrations of the Eu3+ and Tb3+ ions. The present work suggests that these phosphors may have potential application for light-emitting diodes (LEDs)

  18. Research on analysis method for temperature control information of high arch dam construction

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Temperature control,which is directly responsible for the project quality and progress,plays an important role in high arch dam construction.How to discover the rules from a large amount of temperature control information collected in order to guide the adjustment of temperature control measures to prevent cracks on site is the key scientific problem.In this paper,a mathematic logical model was built firstly by means of a coupling analysis of temperature control system decomposition and coordination for high arch dam.Then,an analysis method for temperature control information was presented based on data mining technology.Furthermore,the data warehouse of temperature control was designed,and the artificial neural network forecasting model for the highest temperature of concrete was also developed.Finally,these methods were applied to a practical project. The result showed that the efficiency and precision of temperature control was improved,and rationality and scientificity of management and decision-making were strengthened.All of these researches provided an advanced analysis method for temperature control in the high arch dam construction process.

  19. Results of an integrated structure-control law design sensitivity analysis

    Science.gov (United States)

    Gilbert, Michael G.

    1988-01-01

    Next generation air and space vehicle designs are driven by increased performance requirements, demanding a high level of design integration between traditionally separate design disciplines. Interdisciplinary analysis capabilities have been developed, for aeroservoelastic aircraft and large flexible spacecraft control for instance, but the requisite integrated design methods are only beginning to be developed. One integrated design method which has received attention is based on hierarchal problem decompositions, optimization, and design sensitivity analyses. This paper highlights a design sensitivity analysis method for Linear Quadratic Cost, Gaussian (LQG) optimal control laws, which predicts change in the optimal control law due to changes in fixed problem parameters using analytical sensitivity equations. Numerical results of a design sensitivity analysis for a realistic aeroservoelastic aircraft example are presented. In this example, the sensitivity of the optimally controlled aircraft's response to various problem formulation and physical aircraft parameters is determined. These results are used to predict the aircraft's new optimally controlled response if the parameter was to have some other nominal value during the control law design process. The sensitivity results are validated by recomputing the optimal control law for discrete variations in parameters, computing the new actual aircraft response, and comparing with the predicted response. These results show an improvement in sensitivity accuracy for integrated design purposes over methods which do not include changess in the optimal control law. Use of the analytical LQG sensitivity expressions is also shown to be more efficient that finite difference methods for the computation of the equivalent sensitivity information.

  20. Validating the feedback control of intersegmental coordination by fluctuation analysis of disturbed walking.

    Science.gov (United States)

    Funato, Tetsuro; Aoi, Shinya; Tomita, Nozomi; Tsuchiya, Kazuo

    2015-05-01

    A walking motion is established by feedforward control for rhythmic locomotion and feedback control for adapting to environmental variations. To identify the control variables that underlie feedback control, uncontrolled manifold (UCM) analysis has been proposed and adopted for analyzing various movements. UCM analysis searches the controlled variables by comparing the fluctuation size of segmental groups related and unrelated to the movement of candidate variables, based on the assumption that a small fluctuation size indicates a relationship with the feedback control. The present study was based on UCM analysis and evaluated fluctuation size to determine the control mechanism for walking. While walking, the subjects were subjected to floor disturbances at two different frequencies, and the fluctuation sizes of the segmental groups related to characteristic variables were calculated and compared. The characteristic variables evaluated were the motion of the center of mass, limb axis, and head, and the intersegmental coordination of segmental groups with simultaneous coupled movements. Results showed that the fluctuations in intersegmental coordination were almost equally small for any segment, while fluctuations in the other variables were large in certain segments. Moreover, a comparison of the fluctuation sizes among the evaluated variables showed that the fluctuation size for intersegmental coordination was the smallest. These results indicate a possible relationship between intersegmental coordination and the control of walking.

  1. Time series modeling for analysis and control advanced autopilot and monitoring systems

    CERN Document Server

    Ohtsu, Kohei; Kitagawa, Genshiro

    2015-01-01

    This book presents multivariate time series methods for the analysis and optimal control of feedback systems. Although ships’ autopilot systems are considered through the entire book, the methods set forth in this book can be applied to many other complicated, large, or noisy feedback control systems for which it is difficult to derive a model of the entire system based on theory in that subject area. The basic models used in this method are the multivariate autoregressive model with exogenous variables (ARX) model and the radial bases function net-type coefficients ARX model. The noise contribution analysis can then be performed through the estimated autoregressive (AR) model and various types of autopilot systems can be designed through the state–space representation of the models. The marine autopilot systems addressed in this book include optimal controllers for course-keeping motion, rolling reduction controllers with rudder motion, engine governor controllers, noise adaptive autopilots, route-tracki...

  2. Analysis and control of complex dynamical systems robust bifurcation, dynamic attractors, and network complexity

    CERN Document Server

    Imura, Jun-ichi; Ueta, Tetsushi

    2015-01-01

    This book is the first to report on theoretical breakthroughs on control of complex dynamical systems developed by collaborative researchers in the two fields of dynamical systems theory and control theory. As well, its basic point of view is of three kinds of complexity: bifurcation phenomena subject to model uncertainty, complex behavior including periodic/quasi-periodic orbits as well as chaotic orbits, and network complexity emerging from dynamical interactions between subsystems. Analysis and Control of Complex Dynamical Systems offers a valuable resource for mathematicians, physicists, and biophysicists, as well as for researchers in nonlinear science and control engineering, allowing them to develop a better fundamental understanding of the analysis and control synthesis of such complex systems.

  3. Analysis of Power Converter Losses in Vector Control System of a Self-Excited Induction Generator

    Science.gov (United States)

    Bašić, Mateo; Vukadinović, Dinko; Polić, Miljenko

    2014-03-01

    This paper provides analysis of losses in the hysteresis-driven three-phase power converter with IGBTs and free-wheeling diodes. The converter under consideration is part of the self-excited induction generator (SEIG) vector control system. For the analysis, the SEIG vector control system is used in which the induction generator iron losses are taken into account. The power converter losses are determined by using a suitable loss estimation algorithm reported in literature. The chosen algorithm allows the power converter losses to be determined both by type (switching/conduction losses) and by converter component (IGBT/diode losses). The overall power converter losses are determined over wide ranges of rotor speed, dc-link voltage and load resistance, and subsequently used for offline correction of the overall control system's losses (efficiency) obtained through control system simulations with an ideal power converter. The control system's efficiency values obtained after the correction are compared with the measured values.

  4. Continuous Local Infiltration Analgesia for Pain Control After Total Knee Arthroplasty: A Meta-analysis of Randomized Controlled Trials.

    Science.gov (United States)

    Sun, Xiao-Lei; Zhao, Zhi-Hu; Ma, Jian-Xiong; Li, Feng-Bo; Li, Yan-Jun; Meng, Xin-Min; Ma, Xin-Long

    2015-11-01

    A total knee arthroplasty (TKA) has always been associated with moderate to severe pain. As more research is conducted on the use of continuous local infiltration analgesia (CLIA) to manage pain after a TKA, it is necessary to reassess the efficacy and safety of the TKA method. The purpose of this systematic review and meta-analysis of randomized controlled trials was to evaluate the efficacy and safety of pain control of CLIA versus placebo after a TKA. In January 2015, a systematic computer-based search was conducted in the Medline, Embase, PubMed, CENTRAL (Cochrane Controlled Trials Register), Web of Science, Google database, and Chinese Wanfang databases. This systematic review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement criteria. The primary endpoint was the visual analog scale score after a TKA with rest or mobilization at 24, 48, and 72 hours, which represents the effect of pain control after TKA. The complications of infection, nausea, and whether it prolonged wound drainage were also compiled to assess the safety of CLIA. RevMan 5.30 software was used for the meta-analysis. After testing for publication bias and heterogeneity across studies, data were aggregated for random-effects modeling when necessary. Ten studies involving 735 patients met the inclusion criteria. The meta-analysis revealed that continuous infusion analgesia provided better pain control with rest at 24 hours (mean difference [MD] -12.54, 95% confidence interval [CI] -16.63 to 8.45), and with mobilization at 24 hours (MD -18.27, 95% CI -27.52 to 9.02) and 48 hours (MD -14.19, 95% CI -21.46 to 6.93). There was no significant difference with respect to the visual analog scale score at 48 hours (MD -6.15, 95% CI -13.51 to 1.22, P = 0.10) and 72 hours (MD -3.63, 95% CI -10.43 to 3.16, P = 0.29) with rest and at 72 hours with mobilization (MD -4.25, 95% CI -16.27 to 7.77, P = 0

  5. Modeling and the analysis of control logic for a digital PWM controller based on a nano electronic single electron transistor

    Directory of Open Access Journals (Sweden)

    Rathnakannan Kailasam

    2008-01-01

    Full Text Available This paper describes the modelling and the analysis of control logic for a Nano-Device- based PWM controller. A comprehensive simple SPICE schematic model for Single Electron transistor has been proposed. The operation of basic Single Electron Transistor logic gates and SET flip flops were successfully designed and their performances analyzed. The proposed design for realizing the logic gates and flip-flops is used in constructing the PWM controller utilized for switching the buck converter circuit. The output of the converter circuit is compared with reference voltage, and when the error voltage and the reference are matched the latch is reset so as to generate the PWM signal. Due to the simplicity and accuracy of the compact model, the simulation time and speed are much faster, which makes it potentially applicable in large-scale circuit simulation. This study confirms that the SET-based PWM controller is small in size, consumes ultra low power and operates at high speeds without compromising any performance. In addition these devices are capable of measuring charges of extremely high sensitivity.

  6. A Framework for Flood Risk Analysis and Benefit Assessment of Flood Control Measures in Urban Areas.

    Science.gov (United States)

    Li, Chaochao; Cheng, Xiaotao; Li, Na; Du, Xiaohe; Yu, Qian; Kan, Guangyuan

    2016-01-01

    Flood risk analysis is more complex in urban areas than that in rural areas because of their closely packed buildings, different kinds of land uses, and large number of flood control works and drainage systems. The purpose of this paper is to propose a practical framework for flood risk analysis and benefit assessment of flood control measures in urban areas. Based on the concept of disaster risk triangle (hazard, vulnerability and exposure), a comprehensive analysis method and a general procedure were proposed for urban flood risk analysis. Urban Flood Simulation Model (UFSM) and Urban Flood Damage Assessment Model (UFDAM) were integrated to estimate the flood risk in the Pudong flood protection area (Shanghai, China). S-shaped functions were adopted to represent flood return period and damage (R-D) curves. The study results show that flood control works could significantly reduce the flood risk within the 66-year flood return period and the flood risk was reduced by 15.59%. However, the flood risk was only reduced by 7.06% when the flood return period exceeded 66-years. Hence, it is difficult to meet the increasing demands for flood control solely relying on structural measures. The R-D function is suitable to describe the changes of flood control capacity. This frame work can assess the flood risk reduction due to flood control measures, and provide crucial information for strategy development and planning adaptation. PMID:27527202

  7. A Framework for Flood Risk Analysis and Benefit Assessment of Flood Control Measures in Urban Areas

    Science.gov (United States)

    Li, Chaochao; Cheng, Xiaotao; Li, Na; Du, Xiaohe; Yu, Qian; Kan, Guangyuan

    2016-01-01

    Flood risk analysis is more complex in urban areas than that in rural areas because of their closely packed buildings, different kinds of land uses, and large number of flood control works and drainage systems. The purpose of this paper is to propose a practical framework for flood risk analysis and benefit assessment of flood control measures in urban areas. Based on the concept of disaster risk triangle (hazard, vulnerability and exposure), a comprehensive analysis method and a general procedure were proposed for urban flood risk analysis. Urban Flood Simulation Model (UFSM) and Urban Flood Damage Assessment Model (UFDAM) were integrated to estimate the flood risk in the Pudong flood protection area (Shanghai, China). S-shaped functions were adopted to represent flood return period and damage (R-D) curves. The study results show that flood control works could significantly reduce the flood risk within the 66-year flood return period and the flood risk was reduced by 15.59%. However, the flood risk was only reduced by 7.06% when the flood return period exceeded 66-years. Hence, it is difficult to meet the increasing demands for flood control solely relying on structural measures. The R-D function is suitable to describe the changes of flood control capacity. This frame work can assess the flood risk reduction due to flood control measures, and provide crucial information for strategy development and planning adaptation. PMID:27527202

  8. A review on tomato authenticity: quality control methods in conjunction with multivariate analysis (chemometrics).

    Science.gov (United States)

    Arvanitoyannis, Ioannis S; Vaitsi, Olga B

    2007-01-01

    Authenticity and traceability have been two of the most important issues in the food chain. Authenticity in particular, is closely related with both food quality and safety issues. Vegetables stand for a category of foods heavily affected by adulteration either in terms of geographic origin (national or international level) or production methods (organic or conventional production, fertilizers, pesticides, genetically modified vegetables). This review aims at addressing most of the currently applied methods for ensuring quality control of vegetables; a) instrumental: ion chromatography, high pressure liquid chromatography, atomic absorption spectrophotometry, electronic nose and mass spectroscopy and b) sensory analysis. The results of all the above mentioned methods were analyzed by means of multivariate analysis (principal component analysis, discriminant analysis, cluster analysis, canonical analysis, and factor analysis). All ensuing results and conclusions are summarized in eight comprehensive tables.

  9. Sustainable Use Of Macro-Algae For Biogas Production In Latvian Conditions: A Preliminary Study Through An Integrated Mca And Lca Approach

    Science.gov (United States)

    Pastare, Laura; Romagnoli, Francesco; Lauka, Dace; Dzene, Ilze; Kuznecova, Tatjana

    2014-12-01

    The study focuses on sustainability evaluation of an algae-based energy system in Latvia with a holistic and integrated approach of multi-criteria analysis combined with life cycle assessment (including a practical side - biogas yield experiments of locally available algae). The study shows potential for sustainable use of algae in Latvian conditions and thus that algal biomass can be utilized for the production of biogas. The most sustainable and feasible scenario of using algae for biogas energy production foresees the collection of algae biomass from natural water bodies. Important beneficial effects through the use of algae are related to avoiding global warming potential (GWP) and eutrophication impacts. Biogas batch experiments carried out with the local macrophyte C.demersum have shown a methane yield of 554 l CH4/kg VS.

  10. A Functional Analysis Framework for Modeling, Estimation and Control in Science and Engineering

    CERN Document Server

    Banks, HT

    2012-01-01

    A Modern Framework Based on Time-Tested Material A Functional Analysis Framework for Modeling, Estimation and Control in Science and Engineering presents functional analysis as a tool for understanding and treating distributed parameter systems. Drawing on his extensive research and teaching from the past 20 years, the author explains how functional analysis can be the basis of modern partial differential equation (PDE) and delay differential equation (DDE) techniques. Recent Examples of Functional Analysis in Biology, Electromagnetics, Materials, and Mechanics Through numerous application exa

  11. Energy Conservation Analysis and Control of Hybrid Active Semiactive Suspension with Three Regulating Damping Levels

    Directory of Open Access Journals (Sweden)

    Long Chen

    2016-01-01

    Full Text Available Active suspension has not been popularized for high energy consumption. To address this issue, this paper introduces the concept of a new kind of suspension. The linear motor is considered to be integrated into an adjustable shock absorber to form the hybrid active semiactive suspension (HASAS. To realize the superiority of HASAS, its energy consumption and regeneration mechanisms are revealed. And the system controller which is composed of linear quadratic regulator (LQR controller, mode decision and switch controller, and the sliding mode control based thrust controller is developed. LQR controller is designed to maintain the suspension control objectives, while mode decision and switch controller decides the optimal damping level to tune motor thrust. The thrust controller ensures motor thrust tracking. An adjustable shock absorber with three regulating levels to be used in HASAS is trial produced and tested to obtain its working characteristics. Finally, simulation analysis is made with the experimental three damping characteristics. The impacts of adjustable damping on the motor force and energy consumption are investigated. Simulation results demonstrate the advantages of HASAS in energy conservation with various suspension control objectives. Even self-powered active control and energy regenerated to the power source can be realized.

  12. Analysis and improvement of digital control stability for master-slave manipulator system

    International Nuclear Information System (INIS)

    Some bilateral controls of master-slave system have been designed, which can realize high-fidelity telemanipulation as if the operator were manipulating the object directly. While usual robot systems are controlled by software-servo system using digital computer, little work has been published on design and analysis for digital control of these systems, which must consider time-delay of sensor signals and zero order hold effect of command signals on actuators. This paper presents a digital control analysis for single degree of freedom master-slave system including impedance models of both the human operator and the task object, which clarifies some index for the stability. The stability result shows a virtual master-slave system concepts, which improve the digital control stability. We first analyze a dynamic control method of master-slave system in discrete-time system for the stability problem, which can realize high-fidelity telemanipulation in the continuous-time. Secondly, using the results of the stability analysis, the robust control scheme for master-slave system is proposed, and the validity of this scheme is finally confirmed by the simulation. Consequently, it would be considered that any combination of master and slave modules with dynamic model of these manipulators is possible to construct the stable master-slave system. (author)

  13. Insider Threat - Material Control and Accountability Mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Powell, Danny H [ORNL; Elwood Jr, Robert H [ORNL; Roche, Charles T [ORNL

    2011-01-01

    The technical objectives of nuclear safeguards are (1) the timely detection of diversion of significant quantities of nuclear material from peaceful uses to the manufacture of nuclear weapons or other nuclear explosive devices or for purposes unknown and (2) the deterrence of such diversion by the risk of early detection. The safeguards and security program must address both outsider threats and insider threats. Outsider threats are primarily addressed by the physical protection system. Insider threats can be any level of personnel at the site including passive or active insiders that could attempt protracted or abrupt diversion. This could occur by an individual acting alone or by collusion between an individual with material control and accountability (MC&A) responsibilities and another individual who has responsibility or control within both the physical protection and the MC&A systems. The insider threat is one that must be understood and incorporated into the safeguards posture. There have been more than 18 documented cases of theft or loss of plutonium or highly enriched uranium. The insider has access, authority, and knowledge, as well as a set of attributes, that make him/her difficult to detect. An integrated safeguards program is designed as a defense-in-depth system that seeks to prevent the unauthorized removal of nuclear material, to provide early detection of any unauthorized attempt to remove nuclear material, and to rapidly respond to any attempted removal of nuclear material. The program is also designed to support protection against sabotage, espionage, unauthorized access, compromise, and other hostile acts that may cause unacceptable adverse impacts on national security, program continuity, the health and safety of employees, the public, or the environment. Nuclear MC&A play an essential role in the capabilities of an integrated safeguards system to deter and detect theft or diversion of nuclear material. An integrated safeguards system with

  14. Robot impedance control and passivity analysis with inner torque and velocity feedback loops

    Institute of Scientific and Technical Information of China (English)

    Michele FOCCHI; Gustavo A MEDRANO-CERDA; Thiago BOAVENTURA; Marco FRIGERIO; Claudio SEMINI; Jonas BUCHLI; Darwin G CALDWELL

    2016-01-01

    Impedance control is a well-established technique to control interaction forces in robotics. However, real implementations of impedance control with an inner loop may suffer from several limitations. In particular, the viable range of stable stiffness and damping values can be strongly affected by the bandwidth of the inner control loops (e.g., a torque loop) as well as by the filtering and sampling frequency. This paper provides an extensive analysis on how these aspects influence the stability region of impedance parameters as well as the passivity of the system. This will be supported by both simulations and experimental data. Moreover, a methodology for designing joint impedance controllers based on an inner torque loop and a positive velocity feedback loop will be presented. The goal of the velocity feedback is to increase (given the constraints to preserve stability) the bandwidth of the torque loop without the need of a complex controller.

  15. Numerical Analysis of a Distributed Optimal Control Problem Governed by an Elliptic Variational Inequality

    Directory of Open Access Journals (Sweden)

    Mariela Olguín

    2015-01-01

    Full Text Available The objective of this work is to make the numerical analysis, through the finite element method with Lagrange’s triangles of type 1, of a continuous optimal control problem governed by an elliptic variational inequality where the control variable is the internal energy g. The existence and uniqueness of this continuous optimal control problem and its associated state system were proved previously. In this paper, we discretize the elliptic variational inequality which defines the state system and the corresponding cost functional, and we prove that there exist a discrete optimal control and its associated discrete state system for each positive h (the parameter of the finite element method approximation. Finally, we show that the discrete optimal control and its associated state system converge to the continuous optimal control and its associated state system when the parameter h goes to zero.

  16. Control of modular multilevel converters based on time-scale analysis and orthogonal functions

    DEFF Research Database (Denmark)

    Zarri, L.; Tani, A.; Mengoni, M.;

    2014-01-01

    Modular multilevel converter (MMC) is a promising multilevel topology for high-voltage applications that has been developed in recent years. The control of MMCs has been analyzed in detail in many papers, showing that the converter capacitors can be kept charged and balanced by controlling the...... circulating current of each leg. The set-point signal of the circulating current is probably the most difficult variable to choose. Typically, it is chosen in such a way to control the total energy and the energy unbalance of each leg. Although several theories are available, the control of the circulating...... current is still a complex task and cannot be fully tackled with traditional linear control techniques. In this paper a multiple time-scale analysis is proposed to determine an approximated model of the MMC that can be used to solve the control problem of the capacitor voltages. In addition, it is shown...

  17. INTERIM ANALYSIS OF THE CONTRIBUTION OF HIGH-LEVEL EVIDENCE FOR DENGUE VECTOR CONTROL.

    Science.gov (United States)

    Horstick, Olaf; Ranzinger, Silvia Runge

    2015-01-01

    This interim analysis reviews the available systematic literature for dengue vector control on three levels: 1) single and combined vector control methods, with existing work on peridomestic space spraying and on Bacillus thuringiensis israelensis; further work is available soon on the use of Temephos, Copepods and larvivorous fish; 2) or for a specific purpose, like outbreak control, and 3) on a strategic level, as for example decentralization vs centralization, with a systematic review on vector control organization. Clear best practice guidelines for methodology of entomological studies are needed. There is a need to include measuring dengue transmission data. The following recommendations emerge: Although vector control can be effective, implementation remains an issue; Single interventions are probably not useful; Combinations of interventions have mixed results; Careful implementation of vector control measures may be most important; Outbreak interventions are often applied with questionable effectiveness. PMID:26506739

  18. Fault tree based reliability analysis for digital reactor power control system of nuclear power plant

    International Nuclear Information System (INIS)

    Fault tree method is used for reliability analysis for reactor power control system, including uncertainty analysis and sensitive analysis. 'loss of regulation accident' top event and 'loss of effective control' top event are defined, corresponding fault tree are constructed, and contribution of hardware failure and software failure to system safety are calculated. It points out that common mode failures of software, actuator, sensor and operator's response have significant influence to system reliability in 'loss of regulation accident'; software common mode failure and operators' response have significant contribution to system reliability in 'loss of efficient control accident'. (authors)

  19. Dynamic modeling and controllability analysis of an ethanol reformer for fuel cell application

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, Vanesa M.; Serra, Maria; Riera, Jordi [Institut de Robotica i Informatica Industrial (CSIC-UPC), Llorens i Artigas 4-6, 08028 Barcelona (Spain); Lopez, Eduardo [Institut de Tecniques Energetiques, Universitat Politecnica de Catalunya, Diagonal 647, ed. ETSEIB, 08028 Barcelona (Spain); Planta Piloto de Ingenieria Quimica (CONICET-UNS), Camino de la Carrindanga km7, 8000 Bahia Blanca (Argentina); Llorca, Jordi [Institut de Tecniques Energetiques, Universitat Politecnica de Catalunya, Diagonal 647, ed. ETSEIB, 08028 Barcelona (Spain)

    2010-09-15

    This work presents a controllability analysis of a low temperature ethanol reformer based on a cobalt catalyst for fuel cell application. The study is based on a non-linear dynamic model of a reformer which operates in three separate stages: ethanol dehydrogenation to acetaldehyde and hydrogen, acetaldehyde steam reforming, and water-gas-shift reaction. The controllability analysis is focused on the rapid dynamics due to mass balances and is based on a linearization of the complex non-linear model of the reformer. RGA, CN and MRI analysis tools are applied to the linear model suggesting that a good performance can be obtained with decentralized control for frequencies up to 0.1 rad s{sup -1}. (author)

  20. Codimension-Two Bifurcation Analysis in DC Microgrids Under Droop Control

    Science.gov (United States)

    Lenz, Eduardo; Pagano, Daniel J.; Tahim, André P. N.

    This paper addresses local and global bifurcations that may appear in electrical power systems, such as DC microgrids, which recently has attracted interest from the electrical engineering society. Most sources in these networks are voltage-type and operate in parallel. In such configuration, the basic technique for stabilizing the bus voltage is the so-called droop control. The main contribution of this work is a codimension-two bifurcation analysis of a small DC microgrid considering the droop control gain and the power processed by the load as bifurcation parameters. The codimension-two bifurcation set leads to practical rules for achieving a robust droop control design. Moreover, the bifurcation analysis also offers a better understanding of the dynamics involved in the problem and how to avoid possible instabilities. Simulation results are presented in order to illustrate the bifurcation analysis.

  1. Controlling the onset of turbulence by streamwise traveling waves. Part 1: Receptivity analysis

    CERN Document Server

    Moarref, Rashad

    2010-01-01

    We examine the efficacy of streamwise traveling waves generated by a zero-net-mass-flux surface blowing and suction for controlling the onset of turbulence in a channel flow. For small amplitude actuation, we utilize weakly nonlinear analysis to determine base flow modifications and to assess the resulting net power balance. Receptivity analysis of the velocity fluctuations around this base flow is then employed to design the traveling waves. Our simulation-free approach reveals that, relative to the flow with no control, the downstream traveling waves with properly designed speed and frequency can significantly reduce receptivity which makes them well-suited for controlling the onset of turbulence. In contrast, the velocity fluctuations around the upstream traveling waves exhibit larger receptivity to disturbances. Our theoretical predictions, obtained by perturbation analysis (in the wave amplitude) of the linearized Navier-Stokes equations with spatially periodic coefficients, are verified using full-scale...

  2. Gas turbine microprocessor control system: reliability test and analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kunkel, R.G.; Rowen, W.I.; Withey, D.J.; Schaeffer, D.G.; Buckley, L.P.; Freeman, M.A.; MacFarland, W.J.; Norman, B.G.; Multhaup, H.A.; Roncevich, J.R.

    1985-07-01

    This report presents the results of a program conducted under EPRI Project RP2101-1, ''Gas Turbine Control System Reliability Analysis and Verification.'' This project articulates the operational capabilities of a new SPEEDTRONIC Mark IV gas turbine control system designed to improve reliability and availability of the system. The project was divided into three phases of study, including the Mark IV control system review, a study of reliability analysis and predictions, and a field verification test conducted at the Salt River Project Santan Generating Station, for a period of one year during which 2930 operating hours were logged on a preproduction Mark IV prototype unit. Improvements in the reliability and availability of the control system were demonstrated during this period. The Mark IV control system uses microprocessor technology where the control functions are distributed among four microcomputers. Three are identical and redundant control sections while the fourth handles communications. Powerful on-line diagnostics indicate the faulty section, which includes replaceable elements, and allows panel repair to be done while the gas turbine is operating, and therefore reduces the meantime to repair. Results of this project indicate that this new control system can upon reaching maturity attain established reliability objectives. Most importantly, design improvements were identified early in the program to enable adjustments to be made in the design, and to be checked out during the program. 3 refs., 88 figs., 44 tabs.

  3. Technical Requirements Analysis and Control Systems (TRACS) Initial Operating Capability (IOC) documentation

    Science.gov (United States)

    Hammond, Dana P.

    1991-01-01

    The Technical Requirements Analysis and Control Systems (TRACS) software package is described. TRACS offers supplemental tools for the analysis, control, and interchange of project requirements. This package provides the fundamental capability to analyze and control requirements, serves a focal point for project requirements, and integrates a system that supports efficient and consistent operations. TRACS uses relational data base technology (ORACLE) in a stand alone or in a distributed environment that can be used to coordinate the activities required to support a project through its entire life cycle. TRACS uses a set of keyword and mouse driven screens (HyperCard) which imposes adherence through a controlled user interface. The user interface provides an interactive capability to interrogate the data base and to display or print project requirement information. TRACS has a limited report capability, but can be extended with PostScript conventions.

  4. Temperature and wavelength dependent trap filling in M{sub 2}Si{sub 5}N{sub 8}:Eu (M=Ca, Sr, Ba) persistent phosphors

    Energy Technology Data Exchange (ETDEWEB)

    Smet, Philippe F., E-mail: philippe.smet@ugent.be [LumiLab, Department of Solid State Sciences, Ghent University, Krijgslaan 281-S1, 9000 Gent (Belgium); Center for Nano- and Biophotonics (NB-Photonics), Ghent University (Belgium); Van den Eeckhout, Koen [LumiLab, Department of Solid State Sciences, Ghent University, Krijgslaan 281-S1, 9000 Gent (Belgium); Center for Nano- and Biophotonics (NB-Photonics), Ghent University (Belgium); Bos, Adrie J.J.; Kolk, Erik van der; Dorenbos, Pieter [Delft University of Technology, Faculty of Applied Sciences, 2629 JB Delft (Netherlands)

    2012-03-15

    The evaluation of persistent phosphors is often focused on the processes right after the excitation, namely on the shape of the afterglow decay curve and the duration of the afterglow, in combination with thermoluminescence glow curve analysis. In this paper we study in detail the trap filling process in europium-doped alkaline earth silicon nitrides (Ca{sub 2}Si{sub 5}N{sub 8}:Eu, Sr{sub 2}Si{sub 5}N{sub 8}:Eu and Ba{sub 2}Si{sub 5}N{sub 8}:Eu), i.e., how the persistent luminescence can be induced. Both the temperature at which the phosphors are excited and the spectral distribution of the excitation light on the ability to store energy in the phosphors' lattices are investigated. We show that for these phosphors this storage process is thermally activated upon excitation in the lower 5d excited states of Eu{sup 2+}, with the lowest thermal barrier for europium doped Ca{sub 2}Si{sub 5}N{sub 8}. Also, the influence of co-doping with thulium on the trap filling and afterglow behavior is studied. Finally there exists a clear relation between the luminescence quenching temperature and the trap filling efficiency. The latter relation can be utilized to select new efficient 5d-4f based afterglow phosphors. - Highlights: Black-Right-Pointing-Pointer Orange afterglow in M{sub 2}Si{sub 5}N{sub 8}:Eu(Tm) studied with thermoluminescence spectroscopy. Black-Right-Pointing-Pointer Strong influences of excitation wavelength and temperature on trap filling. Black-Right-Pointing-Pointer Energy level scheme is presented. Black-Right-Pointing-Pointer Relation between trap filling with visible light and thermal quenching behavior.

  5. Economic analysis of atmospheric mercury emission control for coal-fired power plants in China.

    Science.gov (United States)

    Ancora, Maria Pia; Zhang, Lei; Wang, Shuxiao; Schreifels, Jeremy; Hao, Jiming

    2015-07-01

    Coal combustion and mercury pollution are closely linked, and this relationship is particularly relevant in China, the world's largest coal consumer. This paper begins with a summary of recent China-specific studies on mercury removal by air pollution control technologies and then provides an economic analysis of mercury abatement from these emission control technologies at coal-fired power plants in China. This includes a cost-effectiveness analysis at the enterprise and sector level in China using 2010 as a baseline and projecting out to 2020 and 2030. Of the control technologies evaluated, the most cost-effective is a fabric filter installed upstream of the wet flue gas desulfurization system (FF+WFGD). Halogen injection (HI) is also a cost-effective mercury-specific control strategy, although it has not yet reached commercial maturity. The sector-level analysis shows that 193 tons of mercury was removed in 2010 in China's coal-fired power sector, with annualized mercury emission control costs of 2.7 billion Chinese Yuan. Under a projected 2030 Emission Control (EC) scenario with stringent mercury limits compared to Business As Usual (BAU) scenario, the increase of selective catalytic reduction systems (SCR) and the use of HI could contribute to 39 tons of mercury removal at a cost of 3.8 billion CNY. The economic analysis presented in this paper offers insights on air pollution control technologies and practices for enhancing atmospheric mercury control that can aid decision-making in policy design and private-sector investments. PMID:26141885

  6. Economic analysis of atmospheric mercury emission control for coal-fired power plants in China.

    Science.gov (United States)

    Ancora, Maria Pia; Zhang, Lei; Wang, Shuxiao; Schreifels, Jeremy; Hao, Jiming

    2015-07-01

    Coal combustion and mercury pollution are closely linked, and this relationship is particularly relevant in China, the world's largest coal consumer. This paper begins with a summary of recent China-specific studies on mercury removal by air pollution control technologies and then provides an economic analysis of mercury abatement from these emission control technologies at coal-fired power plants in China. This includes a cost-effectiveness analysis at the enterprise and sector level in China using 2010 as a baseline and projecting out to 2020 and 2030. Of the control technologies evaluated, the most cost-effective is a fabric filter installed upstream of the wet flue gas desulfurization system (FF+WFGD). Halogen injection (HI) is also a cost-effective mercury-specific control strategy, although it has not yet reached commercial maturity. The sector-level analysis shows that 193 tons of mercury was removed in 2010 in China's coal-fired power sector, with annualized mercury emission control costs of 2.7 billion Chinese Yuan. Under a projected 2030 Emission Control (EC) scenario with stringent mercury limits compared to Business As Usual (BAU) scenario, the increase of selective catalytic reduction systems (SCR) and the use of HI could contribute to 39 tons of mercury removal at a cost of 3.8 billion CNY. The economic analysis presented in this paper offers insights on air pollution control technologies and practices for enhancing atmospheric mercury control that can aid decision-making in policy design and private-sector investments.

  7. Designing stable finite state machine behaviors using phase plane analysis and variable structure control

    Energy Technology Data Exchange (ETDEWEB)

    Feddema, J.T.; Robinett, R.D.; Driessen, B.J.

    1998-03-10

    This paper discusses how phase plane analysis can be used to describe the overall behavior of single and multiple autonomous robotic vehicles with finite state machine rules. The importance of this result is that one can begin to design provably asymptotically stable group behaviors from a set of simple control laws and appropriate switching points with decentralized variable structure control. The ability to prove asymptotically stable group behavior is especially important for applications such as locating military targets or land mines.

  8. Control room dose analysis for Maanshan PWR plant during design basis loss of coolant accident

    International Nuclear Information System (INIS)

    To address the issue identified in USNRC's Generic Letter 2003-1 that the unfiltered air in-leakage rate through plant's control room during design basis accident may exceed that assumed in the licensing analysis and thus threat the control room habitability, the control room radiation dose analysis of Maanshan PWR plant has to be re-performed to determine the allowable unfiltered air in-leakage rate. The allowable unfiltered air in-leakage rate is to be determined in such a way that the calculated whole body dose in the control room during the most limiting design basis accident must meet the criteria set forth in 10 CFR 50 Appendix A General Design Criteria (GDC) 19. The determined allowable air in-leakage rate is then employed as an acceptable limit to be met by the control room in-leakage test. In this study, the Maanshan plant control room dose analysis model during loss of coolant accident (LOCA) has been established based on USNRC's RADTRAD computer code. Different release and transport paths have been incorporated in this model, including containment leakage, engineered safety feature (ESF) leakage, and control room filtered and un-filtered air in-leakage. The RADTRAD calculation results are compared with Final Safety Analysis Report (FSAR) results to assure that overall consistency is reached. Finally, considering the uncertainties and margin to be maintained between RADTRAD calculation results and GDC-19 dose limits, an allowable unfiltered air in-leakage rate for control room habitability application during LOCA has been well defined. (author)

  9. A rapid analysis of coal with furnace under controlled multiple temperature areas

    Institute of Scientific and Technical Information of China (English)

    PAN Li-li; WU Yin-yi; LIANG Guo-wei; ZHANG Zhe; SHAN Ning

    2008-01-01

    A novel thermogravimetric analyzer system of furnace with multiple temperaturecontroller was described, which mainly decreased the analysis cycle duration down to20 min. Furthermore, the present C591 rapid analyzer system under software can monitorand control some coal physical and chemical properties like change of coal, control com-bustion regulation, operation of coal mixture, and improvement of the turnover rate of thetransportation facilities as well.

  10. BIBLIOGRAPHIC ANALYSIS OF THE REFERENCE SOURCES ON ACCOUNTING AND CONTROL OF FINANCIAL INVESTMENTS

    OpenAIRE

    Zdrenyk, Vasyl

    2014-01-01

    The purpose of the article is to study the subjects and areas of scientific research on the integration and control of financial investments. The analysis of the reference sources made it possible to group the main directions of research and to identify unresolved problems on this basis. The main of which are related to the definition of the nature and characteristics of financial investments, their classification, tasks of accounting and control and so on. D. That means those are theoretical...

  11. Implementation of the Hazard Analysis Critical Control Point (HACCP) system to UF white cheese production line

    OpenAIRE

    Mahmoud El-Hofi; El-Sayed El-Tanboly; Azza Ismail

    2010-01-01

    Background. HACCP, or the Hazard Analysis and Critical Control Point System has been recognised as an effective and rational means of assuring food safety from primary production through to final consumption, using a “farm to table” methodology. The application of this preventive oriented approach would give the food producer better control over operation, better manufacturing practices and greater efficiencies, including reduced wastes. Material and methods. Th...

  12. Light Water Reactor Sustainability Program A Reference Plan for Control Room Modernization: Planning and Analysis Phase

    Energy Technology Data Exchange (ETDEWEB)

    Jacques Hugo; Ronald Boring; Lew Hanes; Kenneth Thomas

    2013-09-01

    The U.S. Department of Energy’s Light Water Reactor Sustainability (LWRS) program is collaborating with a U.S. nuclear utility to bring about a systematic fleet-wide control room modernization. To facilitate this upgrade, a new distributed control system (DCS) is being introduced into the control rooms of these plants. The DCS will upgrade the legacy plant process computer and emergency response facility information system. In addition, the DCS will replace an existing analog turbine control system with a display-based system. With technology upgrades comes the opportunity to improve the overall human-system interaction between the operators and the control room. To optimize operator performance, the LWRS Control Room Modernization research team followed a human-centered approach published by the U.S. Nuclear Regulatory Commission. NUREG-0711, Rev. 3, Human Factors Engineering Program Review Model (O’Hara et al., 2012), prescribes four phases for human factors engineering. This report provides examples of the first phase, Planning and Analysis. The three elements of Planning and Analysis in NUREG-0711 that are most crucial to initiating control room upgrades are: • Operating Experience Review: Identifies opportunities for improvement in the existing system and provides lessons learned from implemented systems. • Function Analysis and Allocation: Identifies which functions at the plant may be optimally handled by the DCS vs. the operators. • Task Analysis: Identifies how tasks might be optimized for the operators. Each of these elements is covered in a separate chapter. Examples are drawn from workshops with reactor operators that were conducted at the LWRS Human System Simulation Laboratory HSSL and at the respective plants. The findings in this report represent generalized accounts of more detailed proprietary reports produced for the utility for each plant. The goal of this LWRS report is to disseminate the technique and provide examples sufficient to

  13. Control design and comprehensive stability analysis of acrobots based on Lyapunov functions

    Institute of Scientific and Technical Information of China (English)

    LAI Xu-zhi; WU Yun-xin; SHE Jin-hua; WU Min

    2005-01-01

    A design method for controllers and a comprehensive stability analysis for an acrobat based on Lyapunov functions are presented. Three control laws based on three Lyapunov functions are designed to increase the energy so as to move the acrobot into the unstable inverted equilibrium position, and solve the problem of posture and energy. The concept of a non-smooth Lyapunov function is employed to analyze the stability of the whole system. The validity of this strategy is demonstrated by simulations.

  14. Analysis of dashpot performance for rotating control drums of a lithium cooled fast reactor concept

    Science.gov (United States)

    Wenzler, C. J.

    1972-01-01

    A dashpot was incorporated in the design of the drive train of the rotating control drum to prevent shock damage to the control drum and drive train at the termination of a scram action. A rotating vane dashpot using reactor coolant lithium as a damping fluid appears to be the best candidate of the various damping devices explored. A performance analysis, results and discussion of vane type dashpots are presented.

  15. Outcome of kidney transplantation between controlled cardiac death and brain death donors: a meta-analysis

    Institute of Scientific and Technical Information of China (English)

    Ming Yingzi; Shao Mingjie; Tian Tingting; She Xingguo; Liu Hong; Ye Shaojun; Ye Qifa

    2014-01-01

    Background Our goal was to evaluate the outcomes of kidney transplants from controlled cardiac death donors compared with brain death donors by conducting a meta-analysis of cohort studies.Methods The PubMed database and EMBASE were searched from January 1980 to July 2013 to identify studies that met pre-stated inclusion criteria.Reference lists of retrieved articles were also reviewed.Two authors independently extracted information on the designs of the studies,the characteristics of the study participants,and outcome assessments.Results Nine cohort studies involving 84 398 participants were included in this meta-analysis; 3 014 received kidneys from controlled cardiac death donors and 80 684 from brain death donors.Warm ischemia time was significantly longer for the controlled cardiac death donor group.The incidence of delayed graft function was 2.74 times (P <0.001) greater in the controlled cardiac death donor group.The results are in favor of the brain death donor group on short-term patient and graft survival while this difference became nonsignificant at mid-term and long term.Sensitivity analysis yielded similar results.No evidence of publication bias was observed.Conclusion This meta-analysis of retrospective cohort studies suggests that the outcome after controlled cardiac death donors is comparable with that obtained using kidneys from brain death donors.

  16. Control and Analysis of Costs Based On Results Account of the ABC method

    Directory of Open Access Journals (Sweden)

    Sorinel Capusneanu

    2011-10-01

    Full Text Available This paper presents a modality of control and cost analysis based on the results account of Activity-Based Costing method. The results account model and situations for determining deviations are presented based on the purpose, composition and classification in the existing literature. There are presented the statements for determining costs deviations resulting from their control and analysis in terms of pilot indicators, all highlighted by a case study application. The article ends with the authors' conclusions about the advantages of these syntheses accounting statements specific to ABC method and using it as a main source of rapid and accurate decision-making for the management at interentity level.

  17. Neural Network Inverse Model Control Strategy: Discrete-Time Stability Analysis for Relative Order Two Systems

    Directory of Open Access Journals (Sweden)

    M. A. Hussain

    2014-01-01

    Full Text Available This paper discusses the discrete-time stability analysis of a neural network inverse model control strategy for a relative order two nonlinear system. The analysis is done by representing the closed loop system in state space format and then analyzing the time derivative of the state trajectory using Lyapunov’s direct method. The analysis shows that the tracking output error of the states is confined to a ball in the neighborhood of the equilibrium point where the size of the ball is partly dependent on the accuracy of the neural network model acting as the controller. Simulation studies on the two-tank-in-series system were done to complement the stability analysis and to demonstrate some salient results of the study.

  18. Magnetic Field Equivalent Current Analysis-Based Radial Force Control for Bearingless Permanent Magnet Synchronous Motors

    OpenAIRE

    Huangqiu Zhu; Hui Li

    2015-01-01

    Bearingless permanent magnet synchronous motors (BPMSMs), with all advantages of permanent magnet motors (PMSMs) and magnetic bearings, have become an important research direction in the bearingless motor field. To realize a stable suspension for the BPMSM, accurate decoupling control between the electromagnetic torque and radial suspension force is indispensable. In this paper, a concise and reliable analysis method based on a magnetic field equivalent current is presented. By this analysis ...

  19. Principal Alarms in Multivariate Statistical Process Control using Independent Component Analysis

    OpenAIRE

    Gonzalez, Isabel; Sanchez, Ismael

    2008-01-01

    Abstract This article proposes a methodology that helps to predict the main mean shifts, denoted as principal alarms, in a non-normal multivariate process using the available in-control data. The analysis is based on the transformation of the observed correlated variables into independent factors using independent component analysis. These independent components allow us to simulate shifts preserving the covariance structure. The graphical representations of those simulated shifts ...

  20. Identification of Energy Efficiency Opportunities through Building Data Analysis and Achieving Energy Savings through Improved Controls

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Taasevigen, Danny J.; Koran, Bill

    2014-09-04

    This chapter will highlight analysis techniques to identify energy efficiency opportunities to improve operations and controls. A free tool, Energy Charting and Metrics (ECAM), will be used to assist in the analysis of whole-building, sub-metered, and/or data from the building automation system (BAS). Appendix A describes the features of ECAM in more depth, and also provide instructions for downloading ECAM and all resources pertaining to using ECAM.

  1. Analysis and Improvement of TCP Congestion Control Mechanism Based on Global Optimization Model

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Network flow control is formulated as a global optimization problem of user profit. A general global optimization flow control model is established. This model combined with the stochastic model of TCP is used to study the global rate allocation characteristic of TCP. Analysis shows when active queue manage ment is used in network TCP rates tend to be allocated to maximize the aggregate of a user utility function Us (called Us fairness). The TCP throughput formula is derived. An improved TCP congestion control mecha nism is proposed. Simulations show its throughput is TCP friendly when competing with existing TCP and its rate change is smoother. Therefore, it is suitable to carry multimedia applications.

  2. Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.

    Science.gov (United States)

    Ainscow, E K; Brand, M D

    1999-08-01

    Control analysis was used to analyse the internal control of rat hepatocyte metabolism. The reactions of the cell were grouped into nine metabolic blocks linked by five key intermediates. The blocks were glycogen breakdown, glucose release, glycolysis, lactate production, NADH oxidation, pyruvate oxidation, mitochondrial proton leak, mitochondrial phosphorylation and ATP consumption. The linking intermediates were intracellular glucose-6-phosphate, pyruvate and ATP levels, cytoplasmic NADH/NAD ratio and mitochondrial membrane potential. The steady-state fluxes through the blocks and the levels of the intermediates were measured in the absence and presence of specific effectors of hepatocyte metabolism. Application of the multiple modulation approach gave the kinetic responses of each block to each intermediate (the elasticities). These were then used to calculate all of the control coefficients, which describe the degree of control each block had over the level of each intermediate, and over the rate of each process. Within this full description of control, many different interactions could be identified. One key finding was that the processes that consumed ATP had only 35% of the control over the rate of ATP consumption. Instead, the reactions that produced ATP exerted the most control over ATP consumption rate; particularly important were mitochondrial phosphorylation (30% of control) and glycolysis (19%). The rate of glycolysis was positively controlled by the glycolytic enzymes themselves (66% of control) and by ATP consumption (47%). Mitochondrial production of ATP, including oxidative, proton leak and phosphorylation processes, had negative control over glycolysis (-26%; the Pasteur effect). In contrast, glycolysis had little control over the rate of ATP production by the mitochondria (-10%; the Crabtree effect). Control over the flux through the mitochondrial phosphorylation block was shared between pyruvate oxidation (23%), ATP consumption (28%) and the

  3. Design and Analysis of a Proposed Timer Controller with Constant Switching Frequency Boost PFC Converter

    Directory of Open Access Journals (Sweden)

    Mr. D. Lenine

    2011-01-01

    Full Text Available The Proposal of this paper is to introduce a new control technique for power factor correction in ac-dc converters. The increasing of non linear loads such as thyristor rectifiers, switching-mode power supplies and adjustable speed drives, generate harmonic currents causing various problems to the other equipment connected to the point of common coupling. There is a disadvantage in the existing PFC control implementation based on conventional hysteresis current control is variable switching frequency. The proposed control technique, it combines the advantages of conventional hysteresis control strategy and the prominent characteristics of constant switching frequency. The fundamental idea consists in determining the ideal time period that exists between the moment when the input current crosses with the reference current and the converter commutation. Thus the input current can oscillate around the reference current with constant frequency of operation. The principal of operation, theoretical analysis, simulation results on a single phase boost converter are presented.

  4. Multiple binary classifications via linear discriminant analysis for improved controllability of a powered prosthesis.

    Science.gov (United States)

    Hargrove, Levi J; Scheme, Erik J; Englehart, Kevin B; Hudgins, Bernard S

    2010-02-01

    This paper describes a novel pattern recognition based myoelectric control system that uses parallel binary classification and class specific thresholds. The system was designed with an intuitive configuration interface, similar to existing conventional myoelectric control systems. The system was assessed quantitatively with a classification error metric and functionally with a clothespin test implemented in a virtual environment. For each case, the proposed system was compared to a state-of-the-art pattern recognition system based on linear discriminant analysis and a conventional myoelectric control scheme with mode switching. These assessments showed that the proposed control system had a higher classification error ( p clothespin usability test implemented in a virtual environment. Furthermore, the system was computationally simple and applicable for real-time embedded implementation. This work provides the basis for a clinically viable pattern recognition based myoelectric control system which is robust, easily configured, and highly usable. PMID:20071277

  5. A Note on Penalized Regression Spline Estimation in the Secondary Analysis of Case-Control Data

    KAUST Repository

    Gazioglu, Suzan

    2013-05-25

    Primary analysis of case-control studies focuses on the relationship between disease (D) and a set of covariates of interest (Y, X). A secondary application of the case-control study, often invoked in modern genetic epidemiologic association studies, is to investigate the interrelationship between the covariates themselves. The task is complicated due to the case-control sampling, and to avoid the biased sampling that arises from the design, it is typical to use the control data only. In this paper, we develop penalized regression spline methodology that uses all the data, and improves precision of estimation compared to using only the controls. A simulation study and an empirical example are used to illustrate the methodology.

  6. [Analysis of the results of the SEIMC External Quality Control Program. Year 2013].

    Science.gov (United States)

    de Gopegui Bordes, Enrique Ruiz; Orta Mira, Nieves; Del Remedio Guna Serrano, M; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2015-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, molecular microbiology and HIV-1, HCV and HBV viral loads. This manuscript presents the analysis of results obtained of the participants from the 2013 SEIMC External Quality Control Programme, except viral loads controls, that they are summarized in a manuscript abroad. As a whole, the results obtained in 2013 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests.

  7. Development of Geometrical Quality Control Real-time Analysis Program using an Electronic Portal Imaging

    International Nuclear Information System (INIS)

    To develop a geometrical quality control real-time analysis program using an electronic portal imaging to replace film evaluation method. A geometrical quality control item was established with the Eclipse treatment planning system (Version 8.1, Varian, USA) after the Electronic Portal Imaging Device (EPID) took care of the problems occurring from the fixed substructure of the linear accelerator (CL-iX, Varian, USA). Electronic portal image (single exposure before plan) was created at the treatment room's 4DTC (Version 10.2, Varian, USA) and a beam was irradiated in accordance with each item. The gaining the entire electronic portal imaging at the Off-line review and was evaluated by a self-developed geometrical quality control real-time analysis program. As for evaluation methods, the intra-fraction error was analyzed by executing 5 times in a row under identical conditions and procedures on the same day, and in order to confirm the infer-fraction error, it was executed for 10 days under identical conditions of all procedures and was compared with the film evaluation method using an Iso-align quality control device. Measurement and analysis time was measured by sorting the time into from the device setup to data achievement and the time amount after the time until the completion of analysis and the convenience of the users and execution processes were compared. The intra-fraction error values for each average 0.1, 0.2, 0.3, 0.2 mm at light-radiation field coincidence, collimator rotation axis, couch rotation axis and gantry rotation axis. By checking the infer-fraction error through 10 days of continuous quality control, the error values obtained were average 1.7, 1.4, 0.7, 1.1 mm for each item. Also, the measurement times were average 36 minutes, 15 minutes for the film evaluation method and electronic portal imaging system, and the analysis times were average 30 minutes, 22 minutes. When conducting a geometrical quality control using an electronic portal imaging

  8. Fuzzy Logic Controller for Static Synchronous Series Compensator with Energy Storage System for Transient Stability Analysis

    Directory of Open Access Journals (Sweden)

    Sona Padma

    2011-01-01

    Full Text Available Problem statement: FACTS devices play a major role in the efficient operation of the complex power system. FACTS devices such as STATCOM, SSSC and IPFC are in increasing usage. With energy storage systems they have a good control over the real as well as reactive power compensation and transient stability improvement. The design of controller for the SSSC with SMES system is analyzed in this study. Approach: The main variables to be controlled in the power system for efficient operation are the voltage, phase angle and impedance. A SSSC is a series connected converter based FACTS control which can provide a series reactive power compensation for a transmission system. With the addition of energy storage device, in addition to the reactive power compensation the real power exchange is also accomplished. Fuzzy logic controller is designed for the efficient operation of the power system with SSSC integrated with energy storage device. From the power reference the current reference is calculated and the error and change in error in the current are calculated in the controller. Results: A three phase to ground fault is simulated in the test system. A comparative analysis of the PI and fuzzy logic control of SSSC with energy storage system for the rotor angle oscillation damping following the disturbance is done. Conclusion: The fuzzy logic controller works efficiently compared to the conventional PI controller for the SSSC with SMES system. Also with energy storage system in the FACTS devices, the efficient operation of the power system is possible.

  9. ANALYSIS OF THE PREDICTIVE DMC CONTROLLER PERFORMANCE APPLIED TO A FEED-BATCH BIOREACTOR

    Directory of Open Access Journals (Sweden)

    J. A. D. RODRIGUES

    1997-12-01

    Full Text Available Two control algorithms were implemented in the stabilization of the dissolved oxygen concentration of the penicillin process production phase. A deterministic and nonstructured mathematical model was used, where were considered the balances of cell, substrate, dissolved oxygen and product formation as well as kinetic of the growth, respiration, product inhibition due to excess of substrate, penicillin hydrolyze, yield factors among cell growth, substrate consumption and dissolved oxygen consumption. The bioreactor was operated in a feed-batch way using an optimal strategy for the operational policy. The agitation speed was used as manipulated variable in order to achieve the dissolved oxygen control because it was found to be the most sensitive one. Two types of control configurations were implemented. First, the PID feedback control with the parameters estimated through Modified Simplex optimization method using the IAE index, and second, the DMC predictive control that had as control parameters the model, prediction and control horizons as well as suppression factor and the trajectory parameter. A sensitivity analysis of these two control algorithms was performed using the sample time and dead time as the index to make stability evaluation. Both configurations showed stable performance, however, the predictive one was found to be more robust in relation to the sample time, as well as the dead time variations. This is a very important characteristic to be considered for the implementation of control scheme in real fermentative process

  10. The beauty of simple adaptive control and new developments in nonlinear systems stability analysis

    Energy Technology Data Exchange (ETDEWEB)

    Barkana, Itzhak, E-mail: ibarkana@gmail.com [BARKANA Consulting, Ramat Hasharon (Israel)

    2014-12-10

    Although various adaptive control techniques have been around for a long time and in spite of successful proofs of stability and even successful demonstrations of performance, the eventual use of adaptive control methodologies in practical real world systems has met a rather strong resistance from practitioners and has remained limited. Apparently, it is difficult to guarantee or even understand the conditions that can guarantee stable operations of adaptive control systems under realistic operational environments. Besides, it is difficult to measure the robustness of adaptive control system stability and allow it to be compared with the common and widely used measure of phase margin and gain margin that is utilized by present, mainly LTI, controllers. Furthermore, customary stability analysis methods seem to imply that the mere stability of adaptive systems may be adversely affected by any tiny deviation from the pretty idealistic and assumably required stability conditions. This paper first revisits the fundamental qualities of customary direct adaptive control methodologies, in particular the classical Model Reference Adaptive Control, and shows that some of their basic drawbacks have been addressed and eliminated within the so-called Simple Adaptive Control methodology. Moreover, recent developments in the stability analysis methods of nonlinear systems show that prior conditions that were customarily assumed to be needed for stability are only apparent and can be eliminated. As a result, sufficient conditions that guarantee stability are clearly stated and lead to similarly clear proofs of stability. As many real-world applications show, once robust stability of the adaptive systems can be guaranteed, the added value of using Add-On Adaptive Control along with classical Control design techniques is pushing the desired performance beyond any previous limits.

  11. The beauty of simple adaptive control and new developments in nonlinear systems stability analysis

    International Nuclear Information System (INIS)

    Although various adaptive control techniques have been around for a long time and in spite of successful proofs of stability and even successful demonstrations of performance, the eventual use of adaptive control methodologies in practical real world systems has met a rather strong resistance from practitioners and has remained limited. Apparently, it is difficult to guarantee or even understand the conditions that can guarantee stable operations of adaptive control systems under realistic operational environments. Besides, it is difficult to measure the robustness of adaptive control system stability and allow it to be compared with the common and widely used measure of phase margin and gain margin that is utilized by present, mainly LTI, controllers. Furthermore, customary stability analysis methods seem to imply that the mere stability of adaptive systems may be adversely affected by any tiny deviation from the pretty idealistic and assumably required stability conditions. This paper first revisits the fundamental qualities of customary direct adaptive control methodologies, in particular the classical Model Reference Adaptive Control, and shows that some of their basic drawbacks have been addressed and eliminated within the so-called Simple Adaptive Control methodology. Moreover, recent developments in the stability analysis methods of nonlinear systems show that prior conditions that were customarily assumed to be needed for stability are only apparent and can be eliminated. As a result, sufficient conditions that guarantee stability are clearly stated and lead to similarly clear proofs of stability. As many real-world applications show, once robust stability of the adaptive systems can be guaranteed, the added value of using Add-On Adaptive Control along with classical Control design techniques is pushing the desired performance beyond any previous limits

  12. Low Probability Tail Event Analysis and Mitigation in BPA Control Area: Task 2 Report

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Shuai; Makarov, Yuri V.; McKinstry, Craig A.; Brothers, Alan J.; Jin, Shuangshuang

    2009-09-18

    Task report detailing low probability tail event analysis and mitigation in BPA control area. Tail event refers to the situation in a power system when unfavorable forecast errors of load and wind are superposed onto fast load and wind ramps, or non-wind generators falling short of scheduled output, causing the imbalance between generation and load to become very significant.

  13. ITC Guidelines on Quality Control in Scoring, Test Analysis, and Reporting of Test Scores

    Science.gov (United States)

    Allalouf, Avi

    2014-01-01

    The Quality Control (QC) Guidelines are intended to increase the efficiency, precision, and accuracy of the scoring, analysis, and reporting process of testing. The QC Guidelines focus on large-scale testing operations where multiple forms of tests are created for use on set dates. However, they may also be used for a wide variety of other testing…

  14. IQC-based robust stability analysis for LPV control of doubly-fed induction generators

    NARCIS (Netherlands)

    Tien, H. N.; Scherer, C. W.; Scherpen, J. M. A.

    2008-01-01

    Parameters of electrical machines are usually varying with time in a smooth way due to changing operating conditions, such as variations in the machine temperature and/or the magnetic saturation. This paper is concerned with robust stability analysis of controlled Doubly-Fed Induction Generators (DF

  15. Interventions to Increase Attendance at Psychotherapy: A Meta-Analysis of Randomized Controlled Trials

    Science.gov (United States)

    Oldham, Mary; Kellett, Stephen; Miles, Eleanor; Sheeran, Paschal

    2012-01-01

    Objective: Rates of nonattendance for psychotherapy hinder the effective delivery of evidence-based treatments. Although many strategies have been developed to increase attendance, the effectiveness of these strategies has not been quantified. Our aim in the present study was to undertake a meta-analysis of rigorously controlled studies to…

  16. Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals

    NARCIS (Netherlands)

    Beek, van T.A.; Montoro, P.

    2009-01-01

    The chemical analysis and quality control of Ginkgo leaves, extracts, phytopharmaceuticals and some herbal supplements is comprehensively reviewed. The review is an update of a similar, earlier review in this journal [T.A. van Beek, J. Chromatogr. A 967 (2002) 21¿55]. Since 2001 over 3000 papers on

  17. Lung cancer risk among bricklayers in a pooled analysis of case-control studies.

    NARCIS (Netherlands)

    Consonni, Dario; De Matteis, Sara; Olsson, Ann; Pesch, Beate; Kromhout, Hans; Straif, Kurt; Brüning, Thomas

    2014-01-01

    OBJECTIVES: Bricklayers may be exposed to several lung carcinogens, including crystalline silica and asbestos. Previous studies reported an excess of lung cancer among these workers. We examined lung cancer risk among bricklayers within SYNERGY, a large international pooled analysis of case-control

  18. Measuring the Extent of European State Aid Control : An Econometric Analysis of the European Commission Decisions

    NARCIS (Netherlands)

    Brouwer, E.; Ozbugday, F.C.

    2011-01-01

    This paper provides an analysis of the European Commission (EC) decisions on state aid control using data on 550 state aid cases approved by the EC between 1998 and 2009. More specifically, we measure the determinants of the duration of state aid, total budget of state aid and daily budget of state

  19. Measuring the Extent of European State Aid Control : An Econometric Analysis of the European Commission Decisions

    NARCIS (Netherlands)

    Brouwer, E.; Ozbugday, F.C.

    2010-01-01

    This paper provides an analysis of the European Commission (EC) decisions on state aid control using data on 550 state aid cases approved by the EC between 1998 and 2009. More specifically, we measure the determinants of the duration of state aid, total budget of state aid and daily budget of state

  20. Financial analysis of brucellosis control for small-scale goat farming in the Bajio Region, Mexico

    NARCIS (Netherlands)

    Oseguera Montiel, D.; Bruce, M.; Frankena, K.; Udo, H.M.J.; Zijpp, van der A.J.; Rushton, J.

    2015-01-01

    Brucellosis is an endemic disease in small-scale goat husbandry systems in Mexico. It is a zoonosis and the economic consequences can be large, although estimates are not available for the Mexican goat sector. Our objective was to conduct a financial analysis of brucellosis control in a prominent da