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Sample records for complicaciones poco usuales

  1. Complicaciones usuales post-drenaje pleural con tubos endotorácico en el trauma torácico no

    OpenAIRE

    Juan C Araujo-Cuauro; Fernando Fernández-Parra; Edwinis Garcia-Fontalvo; Milagros Sánchez

    2016-01-01

    Las lesiones por trauma torácico que ameriten hospitalización, y la inserción de un tubo endotorácico El objetivo de la investigación es identificar las complicaciones post-drenaje pleural con tubos endotorácico en el trauma torácico no quirúrgico. Se trata de estudio prospectivo descriptivo y observacional de las historias clínicas de admisión de los pacientes con traumatismo torácico contuso o penetrante no quirúrgico, que ingresaron durante el período co...

  2. Pocos de Caldas Project

    International Nuclear Information System (INIS)

    1988-01-01

    The first annual report of the Pocos de Caldas Project describes the results of the feasibility study established to test the objectives of the work. Boreholes have been drilled at two sites, the Osamu Utsumi uranium mine and Morro do Ferro, to assess the feasibility of using them as natural analogues of radionuclide migration processes. Detailed geochemical analysis and hydrogeological studies are described. (author)

  3. Virus Zika en Centroamérica y sus complicaciones

    OpenAIRE

    Núñez, Eduardo; Vásquez, Marilin; Beltrán-Luque, Briana; Padgett, Denis

    2016-01-01

    El virus Zika (ZIKV) es un arbovirus, aislado por primera vez en Zika Uganda, reportándose el primer caso en humanos en 1954, desde entonces se han descrito casos en África, Asia, Oceanía y en América. Centroamérica ha sido afectada, por cambios climáticos, pobreza y mal saneamiento ambiental. Su transmisión es vectorial y puede tener transmisión perinatal, transfusiones sanguíneas o por semen infectado. Clínicamente se diferencian poco de Dengue y Chikungunya. Sus complicaciones son principa...

  4. Pocos de Caldas Project

    International Nuclear Information System (INIS)

    1989-01-01

    The second annual report of the Pocos de Caldas Project describes the results of the first phase of the post-feasibility study investigations. Boreholes have been drilled at two sites, the Osamu Utsumi uranium mine and Morro do Ferro, and rock and groundwater samples analysed to provide data on natural analogues of radionuclide migration processes. These detailed geochemical analysis and hydrogeological studies are described, and related to four specific objectives concerning issues of importance in repository performance assessment. (author)

  5. Complicaciones cronicas de la diabetes mellitus

    OpenAIRE

    Isla Pera, Ma. Pilar (María Pilar)

    2012-01-01

    La diabetes mellitus (DM) es una de las enfermedades con mayor impacto sociosanitario, no sólo por su elevada prevalencia, sino, sobre todo, por las consecuencias de las complicaciones crónicas que genera. La hiperglucemia ocasiona daño tanto en el ámbito de la microcirculación como en los grandes vasos provocando lesiones macroangiopáticas y microangiopáticas. Las complicaciones macroangiopáticas se originan a partir de alteraciones o lesiones en los grandes vasos arteriales siendo las más i...

  6. La diabetes mellitus y las complicaciones cardiovasculares

    Directory of Open Access Journals (Sweden)

    Olga Lidia Pereira Despaigne

    2015-05-01

    Full Text Available Las enfermedades cardiovasculares en las personas con diabetes mellitus son más precoces, y suelen presentarse con síntomas y signos atípicos. Igualmente, se ha demostrado que la hiperglucemia es un importante factor de riesgo para las complicaciones microangiopáticas y macroangiopáticas en la diabetes mellitus, y la hiperglucemia posprandial, con glucemia en ayunas normal, es una condición clínica frecuente y un factor de riesgo cardiovascular independiente. Así, en el presente trabajo se exponen algunas consideraciones relacionadas con el control de las dislipidemias, la hipertensión arterial y la antiagregación plaquetaria en el paciente con diabetes mellitus

  7. Poco Petroleum Ltd. annual report 1998

    International Nuclear Information System (INIS)

    1999-01-01

    Calgary-based Poco Petroleum Ltd. is a senior independent oil and gas exploration and development company operating in Western Canada. The company's main goal is to generate sustainable long term growth in cash flow and earnings per share. Poco pursues high impact, deep natural gas exploration in its Northern Region, liquids-rich natural gas in its Western Region, and the smaller Eastern Region is in harvest mode. In 1999, over 80% of average production is forecast to be natural gas and natural gas liquids, with the balance being crude oil. 1998 highlights included: a record daily production was attained for both natural gas and liquids at 490.1 million cubic feet at 40,015 barrels, respectively; cash flow was down only 1% at $333.3 million despite a 30% decline in average prices for crude oil and natural gas liquids; Poco replaced 303% of 1998 oil production, adding proven and probable reserves of 1 trillion cubic feet of natural gas equivalent; the deep gas exploration program was accelerated throu gh the acquisition of Pan East Petroleum Corp. and assets at Monkman Pass, B.C.; and the acquisition of Canrise Resources Ltd. added undeveloped acreage and considerable exploration potential to Poco's Western region

  8. Complicaciones tardías de la radioterapia ocular

    OpenAIRE

    González García, Julio Lázaro; Santos Silva, Dania; Abreu Perdomo, Franklyn Alain; Melgares Ramos, María de los Ángeles; Valdivia Bregado, Yamelyn Tania

    2016-01-01

    La radioterapia es uno de los pilares terapéuticos utilizados en la oncología, no exenta de producir daño ocular, lo que constituye un fenómeno bien establecido. La aparición de complicaciones continúa siendo la principal preocupación de la aplicación de la radioterapia, a pesar del empleo de nuevas estrategias que buscan reducir las complicaciones y mejorar el índice terapéutico. Se presenta una paciente femenina de 63 años con diagnóstico de carcinoma epidermoide de la conjuntiva, moderadam...

  9. Complicaciones mecánicas de los accesos venosos centrales

    OpenAIRE

    Rodrigo Rivas, T.

    2011-01-01

    Las complicaciones mecánicas de los accesos venosos centrales son frecuentes, 2 a 15% y en ocasiones pueden comprometer la vida del paciente. Hay factores que determinan el riesgo de una u otra, que pueden ser modificados o enfrentados de diferente forma para minimizarlo. En esta puesta al día se describen las complicaciones más frecuentes o de mayor gravedad como son: el neumotórax, la embolia aérea, mal-posición del catéter, perforación de grandes venas, punción arterial, arritmias, trom...

  10. Complicaciones neurológicas de la endocarditis infecciosa: controversias

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    Federico A. Silva, MD., MSc

    2011-07-01

    Full Text Available En la endocarditis infecciosa aguda se describen complicaciones neurológicas entre 20% y 40% de los casos, lo cual representa un importante factor que predice morbimortalidad, secuelas y discapacidad. Esta entidad se caracteriza por un amplio espectro clínico debido a su compleja fisiopatología, que involucra entre otros, fenómenos inflamatorios, inmunes, infecciosos y embólicos. A pesar de la notable frecuencia de las complicaciones neurológicas en la endocarditis infecciosa, dadas especialmente por enfermedad cerebrovascular y neuroinfecciones, aun existen controversias acerca de algunos aspectos diagnósticos y terapéuticos, en parte por la poca evidencia disponible, las cuales se discuten a continuación, a partir de una serie de casos atendidos en la Fundación Cardiovascular de Colombia.

  11. Factores asociados a complicaciones de yeyunostomía

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    H. Medina-Franco

    2013-04-01

    Conclusiones: La yeyunostomía se asocia a una elevada frecuencia de complicaciones, tanto médicas como quirúrgicas. Si bien se ha establecido como una mejor alternativa a nutrición parenteral, deberá tomarse en cuenta la morbilidad asociada a la misma antes de establecer su utilización rutinaria como medio de aporte nutricional, particularmente en pacientes con factores asociados al desarrollo de las mismas.

  12. Complicaciones en las puérperas laparotomizadas de urgencia

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    Victor Manuel Sierra Alfonso

    2014-11-01

    Full Text Available La presencia de una complicación intrabdominal postoperatoria después de una laparotomía agrava el estado de salud del paciente y ensombrece el pronóstico, a pesar del uso adecuado de antimicrobianos, de la correcta nutrición y de las ventajas de los cuidados intensivos. Se realizó un estudio retrospectivo descriptivo, con el objetivo de caracterizar las complicaciones en las puérperas, a las que se les practicaron laparotomías de urgencia. Se analizaron las referidas pacientes atendidas en el Hospital Ginecoobstétrico “Piti Fajardo” y en el Hospital General Docente “Aleida Fernández Chardiet”, en el periodo comprendido entre enero del 2010 y diciembre del 2012. La muestra quedó conformada por nueve pacientes. Las complicaciones más presentadas fueron los trastornos hidroelectrolíticos y los trastornos del equilibrio ácido básico. No hubo muerte materna ni fetal. Las puérperas que más complicaciones presentaron fueron las de 35 años y más, con diagnóstico de placenta acreta, hematoma de la cúpula vaginal y atonía uterina. El tiempo de evolución hasta el tratamiento definitivo fue menor de 12 horas

  13. Complicaciones mecánicas de los accesos venosos centrales

    Directory of Open Access Journals (Sweden)

    Dr. T. Rodrigo Rivas

    2011-05-01

    En esta puesta al día se describen las complicaciones más frecuentes o de mayor gravedad como son: el neumotórax, la embolia aérea, mal-posición del catéter, perforación de grandes venas, punción arterial, arritmias, trombosis venosa asociada a catéter venoso central (CVC y oclusión del CVC; algunos elementos de prevención, diagnóstico y tratamiento así como el impacto que puede tener la ultrasonografía rutinaria para instalar un CVC.

  14. Complicaciones tardías de la radioterapia ocular

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    Julio Lázaro González García

    Full Text Available La radioterapia es uno de los pilares terapéuticos utilizados en la oncología, no exenta de producir daño ocular, lo que constituye un fenómeno bien establecido. La aparición de complicaciones continúa siendo la principal preocupación de la aplicación de la radioterapia, a pesar del empleo de nuevas estrategias que buscan reducir las complicaciones y mejorar el índice terapéutico. Se presenta una paciente femenina de 63 años con diagnóstico de carcinoma epidermoide de la conjuntiva, moderadamente diferenciado G-II, invasor (T3N0M0 en ojo izquierdo, que llevó tratamiento quirúrgico y radioterapia superficial complementaria. Como complicación tardía, la paciente presentó catarata radiógena, que recibió tratamiento quirúrgico, además de aneurismas conjuntivales en el área tratada.

  15. Celulitis orbitaria, celulitis frontal y empiema como complicaciones de sinusitis

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    Felipa Elena García García

    Full Text Available La celulitis orbitaria usualmente ocurre como complicación de infecciones de los senos para nasales, y la etiología es principalmente bacteriana. Para realizar un diagnóstico e implantar terapéutica temprana tiene gran importancia reconocer las manifestaciones clínicas de la sinusitis y las edades más afectadas, pues dada su ubicación anatómica, pueden complicarse también con infecciones del sistema nervioso central, que en la edad pediátrica tienen una connotación especial. Se presentan aquí dos pacientes de 10 y 14 años de edad respectivamente, que desarrollaron celulitis orbitaria en un caso, y celulitis frontal y empiema en el otro; así mismo, se muestran los medios diagnósticos utilizados para identificar signos tempranos de posibles complicaciones, con el objetivo que el pediatra pueda identificarlos, así como la terapéutica implantada para dar solución o evitar estas complicaciones.

  16. Complicaciones de la apendicectomía por apendicitis aguda Complications of the appendicectomy due to acute appendicitis

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    Zenén Rodríguez Fernández

    2010-06-01

    Full Text Available INTRODUCCIÓN. La apendicectomía por apendicitis aguda es la operación de urgencia más común en los servicios quirúrgicos, pero no está exenta de complicaciones condicionadas por factores poco conocidos, cuya determinación podría disminuir la morbilidad y mortalidad por esta causa. Fue objetivo de esta investigación identificar algunos factores relacionados con la aparición de complicaciones en los pacientes apendicectomizados por apendicitis aguda. MÉTODOS. Se realizó un estudio descriptivo, observacional y prospectivo de 560 pacientes apendicectomizados, con diagnóstico histopatológico de apendicitis aguda, egresados del Servicio de Cirugía General del Hospital Provincial Docente «Saturnino Lora» de Santiago de Cuba durante el 2006. RESULTADOS. El 21,6 % de la serie sufrió algún tipo de complicación, principalmente la infección del sitio operatorio. Las complicaciones aumentaron en relación con la edad y se presentaron más frecuentemente en los pacientes con enfermedades asociadas, estado físico más precario, mayor tiempo de evolución preoperatoria, así como en las formas histopatológicas más avanzadas de la afección (en las que se incluyen los 4 pacientes fallecidos. La aparición de tales complicaciones puede ser causa de reintervenciones y de aumento de la estadía hospitalaria. CONCLUSIONES. El diagnóstico precoz de la enfermedad y la apendicectomía inmediata con una técnica quirúrgica adecuada previenen la aparición de complicaciones posquirúrgicas y determinan el éxito del único tratamiento eficaz contra la afección más común que causa el abdomen agudo, cuyo pronóstico depende en gran medida y entre otros factores, del tiempo de evolución preoperatoria y de la fase en que se encuentre el proceso morboso al realizar la intervención.INTRODUCTION. Appendicectomy due to acute appendicitis is the commonest urgency operation in surgical services but it is not exempt from complications conditions by

  17. Complicaciones microvasculares en niños con diabetes mellitus tipo I

    OpenAIRE

    Machado1, Karina; Freire, María Victoria; Pérez, María del Luján; Montano4, Alicia

    2013-01-01

    Introducción: la diabetes mellitus (DM1) es la enfermedad crónica endocrinológica más frecuente en pediatría y de mayor repercusión sanitaria por la gravedad de sus complicaciones. Dentro de estas complicaciones tienen especial relevancia la afectación de la microvasculatura, que causa retinopatía, neuropatía y nefropatía. Estas complicaciones, si bien se manifiestan durante la edad adulta, comienzan a desarrollarse en la niñez. Existen normas internacionales para su identificación. Se citan ...

  18. Complicaciones agudas del síndrome nefrótico

    OpenAIRE

    Sandalio Durán Álvarez

    1999-01-01

    Se hace una breve revisión de las complicaciones del síndrome nefrótico que se presentan a veces en forma súbita e inesperada y que pueden poner en riesgo la vida del paciente. Las infecciones son las complicaciones más frecuentes y se destaca la peritonitis primaria como la primera causa. Se analizan las infecciones que se pueden presentar en los pacientes "inmunosuprimidos". Se revisan las complicaciones tromboembólicas y se destaca la importancia de los traumatismos como precipitantes de l...

  19. Pocos de Caldas, Minas Gerais, Brazil: a natural analogue study

    International Nuclear Information System (INIS)

    Smellie, J.

    1989-01-01

    The Pocos de Caldas natural analogue project is an internationally funded project hosted by Brazil; the contributary organizations are SKB (Sweden), NAGRA (Switzerland), DOE (United Kingdom) and the DOE (United States). The Project is a multidisciplinary study of two mineralized areas within an alkaline igneous caldera complex located near the town of Pocos de Caldas in the state of Minas Gerais. One area, the Osamu Utsumi mine, is characterized by redox deposits of secondary remobilized pitchblende, and the other area, Morro do Ferro, comprises a highly weathered deposit of thorium and REE with subordinate uranium. The project, scheduled for three years (1986-1989), is now entering its third and final year. The pilot and feasibility studies, which characterized the first year, helped to establish the major drilling programme and the sampling protocols for both rock and groundwater studies which constituted the major part of the second year. The latest status of the investigations are briefly reported

  20. Se aprende poco : ¿Qué podemos hacer?

    OpenAIRE

    Quinquer, Dolors

    2006-01-01

    La situación en las aulas es más compleja, heterogénea y pluricultural que antes; las competencias que se han de desarrollar se han diversificado, ahora son cognitivas, éticas y sociales, mientras que los marcos organizativos siguen tan rígidos como siempre. En este contexto, comparando España con otros países, parece que los alumnos aprenden poco.¿Qué podemos hacer? 

  1. Enfermedades poco comunes: una prioridad de los sistemas de salud

    OpenAIRE

    RAP

    2017-01-01

    Las enfermedades poco comunes, incluidas las de origen genético, son aquellas enfermedades que tienen una prevalencia baja, menor de 5 casos por cada 10.000 habitantes en la comunidad, según la definición de la Unión Europea. Estas enfermedades tienen ciertas características comunes. Son, en su mayor parte, degenerativas y constituyen una prioridad de los sistemas de salud.

  2. Complicaciones en la hemodiálisis y evaluación de la salud de los pacientes renales crónicos

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    Daiana Coitinho

    2015-09-01

    Full Text Available Objetivo: Identificar las complicaciones clínicas y evaluar la percepción de salud general de los pacientes renales crónicos en hemodiálisis. Metodología: Estudio transversal, con enfoque cuantitativo-descriptivo, realizado en 77 pacientes en hemodiálisis en una Unidad Nefrológica del noroeste de Rio Grande do Sul. La recolección de datos se realizó durante los meses de mayo, junio y julio de 2010 con un formulario de características sociodemográficas/clínicas, también denominado Kidney Disease and Quality of Live-Short Form (kdqol-sftm. Los datos se analizaron mediante estadística descriptiva. El proyecto de investigación fue aprobado por el Comité de Ética en el Consejo nº 02780243000-09. Resultados: La mayoría de los pacientes eran varones (70,1%, adultos mayores (45,4%, casados (59,7%. Los eventos que se produjeron con mayor frecuencia durante la hemodiálisis fueron: debilidad, calambres e hipotensión. En cuanto a la evaluación de la salud general en comparación con la de hace un año, el 39% lo calificó como mucho mejor ahora y el 33,8% como un poco mejor ahora. Conclusiones: A pesar de las complicaciones, actualmente los pacientes valoran mejor su salud.

  3. COMPLICACIONES MÉDICAS DE LOS TRASTORNOS DE LA CONDUCTA ALIMENTARIA

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    Dr. Guillermo Gabler

    2017-11-01

    Full Text Available Los trastornos de la conducta alimentaria presentan una amplia variedad de complicaciones médicas que deben ser consideradas a la hora de la evaluación y que en caso de no ser detectadas precozmente pueden conducir a la muerte del paciente. En el caso de la anorexia nerviosas las complicaciones dependen del bajo peso y la desnutrición; en la bulimia, en cambio, del tipo de purga utilizado; y en el caso del trastorno por atracones se asocian a la obesidad principalmente. El propósito del presente artículo es revisar las principales complicaciones médicas de estas entidades clínicas.

  4. COMPLICACIONES MÉDICAS DE LOS TRASTORNOS DE LA CONDUCTA ALIMENTARIA

    OpenAIRE

    Dr. Guillermo Gabler; Dr. Pablo Olguín; Dr. Alejandra Rodríguez

    2017-01-01

    Los trastornos de la conducta alimentaria presentan una amplia variedad de complicaciones médicas que deben ser consideradas a la hora de la evaluación y que en caso de no ser detectadas precozmente pueden conducir a la muerte del paciente. En el caso de la anorexia nerviosas las complicaciones dependen del bajo peso y la desnutrición; en la bulimia, en cambio, del tipo de purga utilizado; y en el caso del trastorno por atracones se asocian a la obesidad principalmente. El propósito del prese...

  5. Radioactive ores from Agostinho field, Pocos de Caldas (MG), Brazil

    International Nuclear Information System (INIS)

    Fujimori, K.

    1974-01-01

    Aiming to characterize the radioactive minerals of Campo Agostinho, Pocos de Caldas - Brazil, the survey of all natural radiactive elements and their geochemical behaviors, decays and radioactive equilibrium was done. Several models of radioactive instability of the minerals or the radioactive samples were proposed to characterize the geochemistry and the mineralization of radioactive elements. The complete isotopic analysis of the elements was done by high resolution gamma spectrometry, using a Ge(Li) detector, at the temperature of liquid nitrogen, coupled to a multichannel analyser. The sample in radioactive equilibrium of Atomic Energy Comission of United States - A.S. n.6, NBL - New Brunswick Laboratory, was considered as standard sample. Fluorite, zircons, pirite, molibinite, rutile, anatase, niobophyllite, and in small ratio (bellow 0.1%) uranothorianite, coffinite, pyrochlore, monazite and apatite. (M.C.K.) [pt

  6. Biopsia Renal en receptores de Trasplante Renal: cuidados de enfermería y complicaciones

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    Esther Sanz Izquierdo

    Full Text Available Introducción: La biopsia renal percutánea es una herramienta fundamental para el manejo del paciente trasplantado renal. La prueba es primordial para detectar y/o prevenir cualquier disfunción en el injerto, siendo un procedimiento tanto diagnóstico como preconizador. Objetivo: Describir los cuidados de enfermería e identificar las complicaciones derivadas de la biopsia renal en los receptores de Trasplante Renal. Material y métodos: Estudio cuantitativo, descriptivo y transversal realizado en la Unidad de Trasplante Renal, Servicio de Nefrología, del 2008 al 2014. La población objeto de estudio son los receptores de Trasplante Renal (TR. La muestra está compuesta por 368 biopsias renales de seguimiento que ingresan para someterse a una biopsia renal. Los criterios de inclusión son ser mayores de 18 años, trasplantados y que han firmado el consentimiento informado. Se recogen datos sociodemográficos, clínico-asistenciales y complicaciones post-biopsia renal. Resultados: Desde 1980 hasta el 2014 se han llevado a cabo 1868 TR, de 2008 a 2014 se estudiaron 368 biopsias de seguimiento. Se monitoriza la Tensión Arterial y la coagulación pre biopsia. Tras el procedimiento, se controla la presencia de sangrado por micción y constantes vitales. Inicialmente el reposo absoluto era de 24 h, a partir de 2014 se reduce a 6 horas, recomendando reposo relativo al alta, las complicaciones fueron mínimas. Conclusiones: Los resultados indican que la biopsia renal es un procedimiento eficaz, con escasas complicaciones. Destacar el papel de enfermería en la detección precoz de complicaciones.

  7. Tratamiento y complicaciones de las fracturas de seno frontal Frontal sinus fracture treatment and complications

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    S. Heredero Jung

    2007-06-01

    Full Text Available Introducción. Las fracturas de seno frontal se producen como resultado de impactos de alta energía. Un tratamiento inadecuado puede conducir a complicaciones serias incluso muchos años después del traumatismo. Objetivos. Evaluar los datos epidemiológicos y revisar las complicaciones asociadas. Estandarizar el protocolo de tratamiento. Materiales y métodos. Se revisaron 95 pacientes diagnosticados de fracturas de seno frontal pertenecientes al servicio de Cirugía Oral y Maxilofacial del Hospital Universitario 12 de Octubre de Madrid, entre enero de 1990 y diciembre de 2004. Resultados. La edad media de los pacientes revisados es de 34 años. La mayoría son hombres (78% y la causa más frecuente del traumatismo, los accidentes de tráfico. El patrón de fractura más común es el que afecta únicamente a la pared anterior del seno frontal. Las complicaciones descritas son: deformidad estética frontal, sinusitis frontal, mucocele frontal, celulitis fronto-orbitaria, intolerancia al material de osteosíntesis, complicaciones infecciosas del SNC y persistencia de fístula de líquido cefalorraquídeo. Conclusiones. El objetivo ha de estar encaminado a prevenir las complicaciones asociadas a los pacientes con fracturas de seno frontal. Hay que individualizar el protocolo de tratamiento en cada caso. Es recomendable un seguimiento a largo plazo para identificar precozmente las posibles complicaciones.Introduction. Frontal sinus fractures are caused by high velocity impacts. Inappropriate treatment can lead to serious complications, even many years after the trauma. Objectives. To evaluate epidemiological data and associated complications. To standardize the treatment protocol. Materials and methods. the clinical records of 95 patients with frontal sinus fractures treated between January 1990 and December 2004 at the Oral and Maxillofacial Surgery Department, "12 de Octubre" Hospital (Madrid, Spain, were reviewed. Results. The average age of

  8. Complicaciones mecánicas del infarto agudo de miocardio: aunque infrecuentes, potencialmente letales

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    Jerson Quitian Moreno

    2017-09-01

    Full Text Available Aunque la incidencia de complicaciones mecánicas en el infarto agudo de miocardio ha descendido después de la era de la intervención coronaria percutánea, la mortalidad sigue siendo significativa. La ruptura septal ventricular, la regurgitación mitral aguda y la ruptura de la pared libre del ventrículo izquierdo conforman el espectro de complicaciones mecánicas posteriores al infarto agudo de miocardio. La reparación quirúrgica es el pilar del tratamiento; sin embargo, como puente para la cirugía, el manejo médico permite estabilizar al paciente.

  9. Complicaciones del tratamiento de incontinencia urinaria y prolapso de la pelvis

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    Chasta Bacsu, MD

    2013-03-01

    Full Text Available Este artículo tiene como objetivo proporcionar una visión general de las complicaciones asociadas al tratamiento quirúrgico por incontinencia urinaria y prolapso pélvico relacionado con el uso de mallas quirúrgicas. Asimismo, otro de sus objetivos es revisar la nueva clasificación de complicaciones relacionadas con la inserción de prótesis o injertos en la cirugía de piso pélvico femenino otorgada por la Asociación Uroginecológica Internacional (IUGA, por su sigla en inglés / Sociedad de Continencia Internacional (ICS, por su sigla en inglés y por las recientes notificaciones proporcionadas por la Administración de Medicamentos y Alimentación (FDA, por su sigla en inglés.

  10. Complicaciones neurológicas en pacientes con leucemias y linfomas

    OpenAIRE

    Gatti, Carolina; Russo, M. J.; Pazos, M.; Tizio, S.; Bunzel, S.; Borzi, A.

    2010-01-01

    Las leucemias y linfomas pueden afectar el sistema nervioso (SN) por invasión directa o indirecta del tumor. Se ha reportado en 5 a 29% de pacientes con linfomas y en 13% de leucemias agudas. Objetivos: Conocer las complicaciones neurológicas con el fin de implementar un diagnóstico y tratamiento adecuados, mejorar la calidad de vida y el tiempo de supervivencia.

  11. Complicaciones por rotura de aneurismas cerebrales en pacientes operados Hospital Nacional Alberto Sabogal Sologuren 2006 - 2014

    OpenAIRE

    Coasaca Torres, Juan Amilcar

    2016-01-01

    Determinar las complicaciones que se presentan en el periodo preoperatorio, intraoperatorio y postoperatorio de los pacientes operados de aneurisma cerebral roto en el Hospital Nacional Alberto Sabogal Sologuren de 2006 a 2014. Para lo que se realizó un estudio cuantitativo, observacional, descriptivo, transversal y retrospectivo. Se revisaron las Historias Clínicas de los pacientes operados (clipaje) de aneurisma cerebral roto, que reunían los criterios de inclusión. La data obtenida fue eva...

  12. Complicaciones y costos asociados a la varicela en niños inmunocompetentes

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    Sáez-Llorens Xavier

    2002-01-01

    Full Text Available Objetivos. La varicela es una infección común de la infancia en países que no han incorporado la vacunación correspondiente en sus calendarios vacunales. Generalmente es benigna en niños inmunocompetentes y no necesita tratamiento. Los objetivos de este estudio consistieron en investigar la frecuencia y características de las complicaciones de la varicela que requieran tratamiento hospitalario en niños inmunocompetentes y el curso clínico de los hijos de madres con varicela perinatal. Además, se calculó el gasto hospitalario asociado a la varicela en los niños estudiados. Métodos. Estudio retrospectivo de los expedientes clínicos de niños con varicela ingresados en el Hospital del Niño de Panamá, de enero de 1991 a diciembre de 2000. Se analizaron el tipo de complicaciones, el curso clínico y los costos hospitalarios de los pacientes afectados por varicela. Resultados. De 5 203 niños atendidos en consultas externas, 568 (11% fueron hospitalizados. En el estudio se incluyeron 513 niños: 381 (74% con varicela adquirida en la comunidad, 92 (18% hijos de madres con varicela y 40 (8% con varicela nosocomial. Las complicaciones más frecuentes fueron las infecciones cutáneas y subcutáneas (45%, las infecciones respiratorias (25% y las alteraciones neurológicas (7%. Las complicaciones respiratorias y cutáneas ocurrieron a menor edad y en fases más tempranas de la varicela que las alteraciones neurológicas. Trece niños (2,5% fallecieron, con una letalidad del 8% para la varicela con complicaciones respiratorias y neurológicas y nula para las complicaciones cutáneas. Sesenta de los 92 (65% hijos de madres con varicela no desarrollaron la enfermedad y ninguno falleció. En cambio, 2 de los 32 neonatos (6% con varicela perinatal fallecieron. La duración media de la hospitalización fue de 8,9 (1 a 27 días. Se utilizó farmacoterapia parenteral en una gran proporción de los niños, especialmente antibióticos (54%, aciclovir

  13. Calidad de vida y complicaciones en el paciente diabético. Estudio descriptivo en farmacia comunitaria

    Directory of Open Access Journals (Sweden)

    Mateos Sánchez M

    2013-05-01

    Full Text Available INTRODUCCIÓN La investigación de la percepción de la calidad de vida en relación con las complicaciones de la diabetes permite identificar necesidades en estos pacientes. El objetivo de este trabajo es detectar cómo influyen las complicaciones crónicas de la DM2 en la calidad de vida del paciente en el medio rural. MATERIAL Y MÉTODOS Estudio observacional transversal en la zona básica de salud de Lumbrales (Salamanca. Se elaboró un cuestionario dividido en cuatro bloques: variables sociodemográficas, situación clínica de la diabetes (pacientes con complicaciones, número de complicaciones, tipo de complicaciones, retinopatía, neuropatía, cardiopatía, nefropatía, calidad de vida general y calidad de vida del paciente diabético (EsDQOL, validado del DQOL. RESULTADOS 156 pacientes con DM2: 63 hombres y 93 mujeres. Edad media, 73 años; 121 pacientes (80% sin certificado de estudios y 46 (29% presentan alguna complicación. Los cuatro bloques del EsDQOL (satisfacción,impacto, preocupación socio / vocacional, preocupación relacionada con la diabetes presentan valores superiores para los pacientes con complicaciones. Esta tendencia es igual para todas las complicaciones. DISCUSIÓN Los resultados apuntan a que los pacientes del medio rural con DM2 que presentan complicaciones crónicas perciben peor calidad de vida. También que cada una de las complicaciones crónicas estudiadas individualmente afectan negativamente en la calidad de vida. Se debe tener en cuenta que la información de complicaciones diabéticas está basada en la historia clínica y no se determinó su severidad. Es necesario investigar de qué modo afecta a la calidad de vida de los pacientes diabéticos el grado de cada complicación.

  14. Percepciones de los hombres sobre las complicaciones asociadas a la mutilación genital femenina

    Directory of Open Access Journals (Sweden)

    Ismael Jiménez-Ruiz

    2016-07-01

    Conclusiones: Los participantes procedentes de países donde se realiza la mutilación genital femenina, contrarios a mantener esta práctica, muestran un mayor conocimiento de las consecuencias negativas que los que se manifiestan a favor. El diseño de herramientas y programas de sensibilización destinados a la lucha contra la mutilación genital femenina debe visibilizar las complicaciones sobre la salud de las mujeres y las niñas, e incluir intervenciones familiares que impliquen a los hombres en el proceso de erradicación de esta práctica.

  15. Síndrome metabólico durante el embarazo: Complicaciones materno-fetales

    OpenAIRE

    Yépez, Mayel Cristina; Zeppenfel, María Eugenia; Colón, José Antonio; Zimmer, Eveline

    2011-01-01

    Objetivo: Determinar la asociación entre el síndrome metabólico y las complicaciones maternas, fetales y neonatales, en un grupo de embarazadas entre agosto 2008 y septiembre 2009. Ambiente: Servicio Prenatal de la Maternidad “Concepción Palacios”. Métodos: Estudio prospectivo, longitudinal, comparativo, con una muestra de 130 embarazadas, 38 cumplieron los criterios de la Federación Internacional de Diabetes para síndrome metabólico y 92 fueron el grupo control. Resultados: El promedio de ed...

  16. Reparación endovascular torácica aórtica (TEVAR: un enfoque sobre complicaciones

    Directory of Open Access Journals (Sweden)

    Ali Azizzadeh

    2010-01-01

    Full Text Available La reparación endovascular torácica (TEVAR se ha constituido como una alternativa válida para la reparación de los aneurismas torácicos, al ser menos agresiva. Una reciente revisión sistemática y metaanálisis de estudios comparativos confirma que TEVAR, cuando se compara con la cirugía abierta, puede reducir la muerte precoz, la paraplejía, insuficiencia renal, transfusiones, reoperación por hemorragia, complicaciones cardíacas, neumonía y estancia hospitalaria. Esta revisión se referirá a algunas de las complicaciones del procedimiento. Éstas incluyen: mortalidad, accidente cerebrovascular, isquemia medular, disección retrógrada, disfunción del dispositivo, complicaciones del acceso, endofuga y migración.

  17. Calidad de vida y complicaciones en el paciente diabético. Estudio descriptivo en farmacia comunitaria

    OpenAIRE

    Mateos Sánchez M

    2013-01-01

    INTRODUCCIÓN La investigación de la percepción de la calidad de vida en relación con las complicaciones de la diabetes permite identificar necesidades en estos pacientes. El objetivo de este trabajo es detectar cómo influyen las complicaciones crónicas de la DM2 en la calidad de vida del paciente en el medio rural. MATERIAL Y MÉTODOS Estudio observacional transversal en la zona básica de salud de Lumbrales (Salamanca). Se elaboró un cuestionario dividido en cuatro bloques: variables sociod...

  18. Calidad de vida y complicaciones en el paciente diabético. Estudio descriptivo en farmacia comunitaria

    OpenAIRE

    Mateos Sánchez, Mercedes

    2013-01-01

    INTRODUCCIÓN La investigación de la percepción de la calidad de vida en relación con las complicaciones de la diabetes permite identificar necesidades en estos pacientes. El objetivo de este trabajo es detectar cómo influyen las complicaciones crónicas de la DM2 en la calidad de vida del paciente en el medio rural.MATERIAL Y MÉTODOS Estudio observacional transversal en la zona básica de salud de Lumbrales (Salamanca). Se elaboró un cuestionario dividido en cuatro bloques: variables sociodemog...

  19. Relación entre las complicaciones y la calidad de vida del paciente en hemodiálisis

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Cuevas-Budhart

    Full Text Available Resumen Introducción: Los pacientes con Enfermedad Renal Crónica (ERC son tratados con terapias de diálisis. Dentro de este tipo de tratamiento se encuentran la Diálisis Peritoneal (DP y Hemodiálisis (HD. Los pacientes sometidos a HD tienen una evolución imprevisible por las complicaciones del tratamiento y/o complicaciones propias de la ERC. Estas aumentan el número de hospitalizaciones y deterioran la calidad de vida (CV. Objetivos: Evaluar la calidad de vida de pacientes en hemodiálisis y determinar la asociación entre las complicaciones y la CV. Material y Método: Estudio transversal analítico en 157 pacientes en HD (75 hombres, 82 mujeres, mayores de 18 años y con más de 3 meses en tratamiento. La CV se evaluó con el instrumento KDQOL-36, el cual, mide 5 dimensiones en escala del 0 al 100. Se realizó un análisis bivariado, ANOVA y regresión múltiple para evaluar la relación de cada una de las dimensiones con edad, sexo, ocupación, estado civil, escolaridad, tipo de acceso venoso, tiempo con la ERC, con la HD y complicaciones de la ERC y la HD. Resultados: La edad promedio fue de 50.9 años. El 77% de los participantes presentaron complicaciones, 69.4% por HD, 5% por evolución de la ERC y 25.6% ambas complicaciones. En el análisis multivariado se encontró que la presencia de ambas complicaciones deteriora más la calidad de vida que las ocasionadas únicamente por el tratamiento de HD. Conclusión: Las complicaciones del tratamiento de hemodiálisis aunadas a las de la ERC deterioran en gran medida la calidad de vida del paciente.

  20. Frecuencia y severidad de complicaciones de 1,056 broncoscopías en la edad pediátrica

    Directory of Open Access Journals (Sweden)

    Ambrosio Aguilar-Aranda

    2017-06-01

    Full Text Available INTRODUCCIÓN: la endoscopía constituye uno de los avances más grandes en el diagnóstico de enfermedades pulmonares. Ésta ha sido considerada como un procedimiento seguro debido al bajo índice de complicaciones relacionadas con el procedimiento, la enfermedad de origen y el manejo anestésico. OBJETIVO: describir la frecuencia y severidad de las complicaciones de broncoscopías en edad pediátrica. MATERIALES Y MÉTODOS: estudio transversal descriptivo de marzo del 2006 adiciembre del 2014, en un hospital de tercer nivel, a quienes se les realizó broncoscopía flexible de fibra óptica. Se identificaron complicaciones menores o mayores agrupadas en fisiológicas, infecciosas, mecánicas y anestésicas. Los resultados se presentaron con frecuencias y porcentajes para variables cualitativas y medianas y rangos para cuantitativas. RESULTADOS: el estudio incluyó 1059 pacientes, sexo masculino 648 (61%, con un rango de edad de 0 a 192 meses, con patología respiratoria de base n = 842 (80%. Estudio diagnóstico n = 898 (85%, terapéutico n = 161 (15%. Complicaciones menores n = 69 (6.5% y mayores n = 14 (1.5%; estas últimas sólo en estudios diagnósticos.De las complicaciones menores en 55 pacientes (5.2% se presentó por lo menos una complicación aislada y en 14 (1.3% se presentaron más de una complicación. Complicaciones mayores más frecuentes: arritmia n = 7 y desaturación grave n = 7. En cinco pacientes con complicaciones mayores se requirieron maniobras de reanimación; cuatro ingresaron a la unidad de terapia intensiva pediátrica y sólo uno requirió traqueotomía urgente. CONCLUSIONES: la broncoscopía es un procedimiento seguro con una frecuencia baja de complicaciones.

  1. Complicaciones infecciosas de la diálisis peritoneal ambulatoria en niños

    Directory of Open Access Journals (Sweden)

    Diana Patricia Durán Casal

    Full Text Available Introducción: la diálisis peritoneal es la mejor alternativa terapéutica para los niños con enfermedad renal crónica terminal, y en las modalidades de diálisis peritoneal ambulatoria ha permitido el tratamiento fuera del hospital, lo que proporciona un mejor estilo y calidad de vida. No es un método exento de riesgos. Las complicaciones infecciosas relacionadas a la diálisis peritoneal son la causa más importante de morbilidad y es la peritonitis su principal complicación. Objetivo: determinar retrospectivamente la frecuencia y las características de complicaciones infecciosas relacionadas al proceder dialítico. Métodos: nuestro hospital es referente como unidad de diálisis pediátrica del país, así que recibe la mayoría de los niños con enfermedad renal crónica terminal de Cuba. Se revisaron los expedientes clínicos de niños con enfermedad renal crónica terminal en programa de diálisis peritoneal ambulatoria en el Hospital Pediátrico de Centro Habana durante el período 2008-2011. Resultados: se estudiaron 12 pacientes con un promedio de edad de 11 años, 58 % del sexo femenino. Se documentaron 24 episodios infecciosos. Las complicaciones encontradas fueron infección del sitio de salida del catéter, con 62,5 %, peritonitis 33,3 % e infección del túnel submucoso 4,2 %. Predominaron cultivos positivos a bacterias grampositivas (66,7 %. Las bacterias más comunes fueron: Staphylococcus coagulasa positivo (48 % y Staphylococcus coagulasa negativo (22 %. Otros gérmenes identificados fueron E. coli, Enterobacter spp. y Candida spp., con 8,3 % respectivamente. Conclusiones: la infección del sitio de salida del catéter fue la complicación infecciosa más frecuente en nuestra serie. Las bacterias grampositivas son los gérmenes más comunes que causan infección del sitio de salida y peritonitis en pacientes en diálisis peritoneal ambulatoria.

  2. Churg-Strauss syndrome: a case with unusual manifestations; Sindrome de Churg-Strauss: a proposito de un caso con manifestaciones poco usuales

    Energy Technology Data Exchange (ETDEWEB)

    Restrepo, Mauricio; Gonzalez, Luis Alonso; Vasquez, Gloria

    2008-07-01

    Churg-Strauss syndrome, a necrotizing systemic vasculitis which involves the small and (more rarely) the medium-sized vessels, is a primary vasculitis strongly associated with anti neutrophil cytoplasm antibodies (ANCA). It is characterized by the presence of asthma, eosinophilia and extravascular eosinophilic granulomas. Herein, we report a 36-year-old woman with a history of late onset asthma and allergic rhinitis who developed central nervous system involvement, peripheral neuropathy, leucocytoclastic vasculitis and eosinophilia. Interestingly, unusual clinical manifestations of Churg-Strauss syndrome such as mesenteric micro aneurysms and jaw claudication were present in this particular patient. A brief review of the literature of Churg-Strauss syndrome is presented.

  3. Complicaciones pulmonares asociadas a ventilación mecánica en el paciente neonatal

    OpenAIRE

    Cristabel Torres-Castro; Jaime Valle-Leal; Alba J. Martínez-Limón; Zaira Lastra-Jiménez; Lesvia Carmina Delgado-Bojórquez

    2016-01-01

    Introducción: Se buscó determinar la incidencia de complicaciones pulmonares asociadas a ventilación mecánica en pacientes ingresados a un servicio de cuidados intensivos neonatales (UCIN) en un hospital de 2° nivel. Metodología: Estudio analítico retrospectivo en expedientes de recién nacidos ingresados a una sala de UCIN y que recibieron ventilación mecánica en un hospital de segundo nivel de atención médica. Se recabaron datos demográficos, de la ventilación mecánica, la intubación y co...

  4. HEMOGLOBINA GLICOSILADA COMO ELEMENTO PRONÓSTICO EN LAS COMPLICACIONES MACROVASCULARES DE LA DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    Agnes Fajardo Matarrita

    2012-04-01

    Full Text Available En este artículo se discute la información obtenida respecto del cuidado enfermero brindado a personas portadoras de Diabetes Mellitus tipo 2 relacionada con la elevación de la hemoglobina glicolisada (Hba1c como factor pronóstico para el desarrollo de complicaciones. Se realizó una búsqueda de la mejor información científica disponible para construir el estado de la cuestión. Posteriormente, se estableció una pregunta en formato PICO (pacientes, intervención, comparación, observación y se procedió a establecer estrategias de búsqueda en las diferentes bases de datos sugeridas en el Curso de Práctica Clínica de Enfermería Basada en la Evidencia impartido por CIEBE-CR, entre las que se encuentran PUBMED, EBSCO HOST, principalmente. El análisis crítico se llevó a cabo mediante las recomendaciones que brinda CASPe y se comparó con la práctica realizada en el Hospital de la Anexión. El control intensivo de la glicemia, el cual incluye agentes orales, la insulina y la intervención cardiovascular múltiple reflejada en hemoglobinas glicosilada menores a 7, indicó que existía una evidente disminución en la incidencia de eventos macrovasculares mayores tales como el infarto agudo al miocardio, el ictus no fatal y el accidente vascular cerebral. De acuerdo con la evidencia, mantener la hemoglobina glicosilada dentro de parámetros normales disminuye el riesgo de sufrir complicaciones macrovasculares de esta patología en comparación con aquellos pacientes que manejan hemoglobina glicosiladaalta.

  5. Diabetes Mellitus en el servicio de urgencias: manejo de las complicaciones agudas en adultos

    Directory of Open Access Journals (Sweden)

    Eder A. Hernández-Ruiz

    2008-01-01

    Full Text Available La Diabetes Mellitus (DM es una enfermedad de alta prevalencia, reconocida como un problema de salud pública, debido a sus altas tasas de morbilidad y mortalidad asociadas. Diferentes estudios han documentado que la falta de adherencia al tratamiento, constituye uno de los principales factores desencadenantes para las descompensaciones agudas en el paciente diabético. Dentro del espectro de dichas alteraciones se encuentran las crisis hiperglicémicas agudas, las cuales se han dicotomizado en dos entidades clínicas: la Cetoacidosis Diabética (CAD y el Estado Hiperglicémico Hiperosmolar (EHH, que constituyen complicaciones metabólicas potencialmente fatales en el corto plazo y de las cuales pueden encontrarse cuadros superpuestos. Se han establecido criterios diagnósticos específicos buscando realizar un diagnóstico diferencial acertado, que permita un tratamiento idóneo; sin embargo, las tasas de morbilidad y mortalidad siguen siendo considerables. Por su parte, la Hipoglicemia también constituye una emergencia médica que, de no ser tratada oportunamente, puede ocasionar daño neurológico permanente e incluso la muerte. De lo anterior se deduce la importancia de que existan guías claras de manejo de estas alteraciones en todos los centros y servicios donde se preste atención médica de urgencias. Se siguen realizando investigaciones en busca de nuevas estrategias diagnósticas y terapéuticas que permitan un manejo más integral de la DM y sus complicaciones, en aras de mejorar la calidad de vida de los pacientes.

  6. Complicaciones neurológicas de la endocarditis infecciosa: controversias Neurological complications of infective endocarditis: controversies

    Directory of Open Access Journals (Sweden)

    Federico A Silva

    2011-07-01

    Full Text Available En la endocarditis infecciosa aguda se describen complicaciones neurológicas entre 20% y 40% de los casos, lo cual representa un importante factor que predice morbimortalidad, secuelas y discapacidad. Esta entidad se caracteriza por un amplio espectro clínico debido a su compleja fisiopatología, que involucra entre otros, fenómenos inflamatorios, inmunes, infecciosos y embólicos. A pesar de la notable frecuencia de las complicaciones neurológicas en la endocarditis infecciosa, dadas especialmente por enfermedad cerebrovascular y neuroinfecciones, aun existen controversias acerca de algunos aspectos diagnósticos y terapéuticos, en parte por la poca evidencia disponible, las cuales se discuten a continuación, a partir de una serie de casos atendidos en la Fundación Cardiovascular de Colombia.Neurological complications of acute infective endocarditis are described in 20%-40% of cases, representing an important predictive factor of morbidity, mortality, sequels and disability. Acute endocarditis is characterized by a wide clinical spectrum due to its complex physiopathology that involves inflammatory, immune, infectious and embolic phenomena. Despite the remarkable frequency of neurological complications in the infective endocarditis especially by cerebrovascular disease and neuroinfections, there are still some controversies about some diagnostic and therapeutic aspects, partly because of the little evidence available. This paper describes a number of cases seen in the Fundación Cardiovascular de Colombia and discusses some aspects related with the diagnosis and treatment of the neurological complications of acute endocarditis.

  7. Complicaciones del trauma craneoencefálico severo en la unidad de cuidados intensivos pediátricos

    Directory of Open Access Journals (Sweden)

    Andrés Andrés Matos

    2011-09-01

    Full Text Available Introducción: el trauma craneoencefálico severo es responsable de serias complicaciones médicas que exacerban la lesión cerebral secundaria, y frecuentemente son la causa de muerte. Ojetivo: conocer las particularidades de las complicaciones médicas en pacientes con trauma craneoencefálico severo en la unidad de cuidados intensivos del hospital pediátrico "Octavio de la Concepción y de la Pedraja" durante los años comprendidos entre 2007-2009. Métodos: estudio descriptivo en pacientes con trauma craneoencefálico, durante el período comprendido entre los años 2007-2009, para analizar las complicaciones que influyeron en su evolución clínica. Resultados: la edad más representada fue la comprendida entre los 11-15 años (56,90 %; los pacientes incluidos en el grupo de 1-5 años resultaron más vulnerables a las complicaciones médicas. Las fracturas inestables (62,96 %, la rotura de vísceras macizas (51,85 % y la insuficiencia respiratoria (44,44 % fueron las manifestaciones clínicas más evidentes al momento del ingreso. En la Unidad de Cuidados Intensivos las complicaciones médicas frecuentes resultaron ser los trastornos hidroelectrolíticos (94,28 % y la desnutrición (77,14 %. La hiperglicemia y el distrés respiratorio se relacionaron de manera significativa con la mortalidad. El 92,59 % de los fallecidos sumaron 3 puntos en la escala de Glasgow. La ventilación mecánica fue independiente de las complicaciones médicas. Conclusiones: los traumas de cráneo severos son la base para el desarrollo de varias y graves complicaciones que plantean muchos problemas en la práctica médica.

  8. 222Rn determination in mineral waters from the Pocos de Caldas Plateau in Brazil

    International Nuclear Information System (INIS)

    Taddei, M.H.T.; Silva, N.C.; Cipriani, M.

    2002-01-01

    It is estimated that 50% of the radioactive effective dose equivalent to man comes from radon and its radioactivity daughters. The main 222 Rn sources are the soils, building materials and potable waters. There is an especial interest in spas waters with high natural radioactivity. It's considered that the use of these waters as drinking waters is a significant radiation exposure factor, and it is worthwhile to assess the consequent dose. Such estimation has been made for the Pocos de Caldas Plateau, which is a region of high natural radioactivity, from volcanic origin, containing several spas (Aguas da Prata, Caldas, Pocos de Caldas and Andradas). The 222 Rn content was determined in 23 spring waters in Pocos de Caldas and neighboring cities. In water sampling, modified Marinelli flasks were used. The determinations were effected with a high resolution gamma ray spectrometer. High concentration variations were observed in the collected mineral waters, the highest values having been found in Fonte Villela's waters, in Aguas da Prata town (926 Bq/l); Grande Hotel's in Caldas Town (420 Bq/l) and COLAB's in Pocos de Caldas region (289 Bq/l). The annual whole body effective dose equivalent estimate for adult due to water ingestion, using the Crowford-Brown's biokinetic model's adult dose conversion factors, was higher than 1 mSv/year in 61% of the analyzed waters. (author)

  9. Complicaciones tardías en diabetes mellitus tipo 2 en el Hospital II Essalud - Cañete

    Directory of Open Access Journals (Sweden)

    Charlton Fernando Untiveros Mayorga

    2004-04-01

    Full Text Available Objetivo: Determinar las características clínicas y las complicaciones tardías en los pacientes con diabetes tipo 2 atendidos en los consultorios de medicina general y del Programa de Diabetes del Hospital II EsSALUD-Cañete. Material y Métodos: Se realizó un estudio descriptivo de serie de casos en el que se evaluaron 94 pacientes con diabetes tipo 2 elegidos aleatoriamente durante su control ambulatorio, realizándose una entrevista y evaluación clínica durante los meses de junio y julio del 2001. Resultados: La población de pacientes estudiada tuvo una edad promedio de 64.56 + 11.61. Cincuenta y tres pacientes eran mujeres (56.4%. El 68.1% de los pacientes recibían hipoglicemiantes orales y el 11.7% requerían del uso de insulina. Los transtornos lipídicos predominantes fueron la elevación del LDL-Colesterol y disminución del HDL-Colesterol. La retinopatía diabética (88.9% e hipertensión arterial (61.3% fueron las complicaciones más frecuentes. Vasculopatía periférica, neuropatía periférica y neuropatía autonómica fueron otras complicaciones crónicas frecuentes halladas en la población de estudio. Conclusiones: Las complicaciones cardiovasculares (micro y macrovasculares en la población de pacientes con diabetes tipo 2 atendidos ambulatoriamente en el Hospital II EsSALUD-Cañete fueron las más frecuentes. (Rev Med Hered 2004; 15:64-69.

  10. Caracterización de pacientes diabéticos de tipo 2 con complicaciones vasculares y riesgo de ateroesclerosi

    Directory of Open Access Journals (Sweden)

    Milagros Violeta Font Difour

    2014-12-01

    Full Text Available Se realizó un estudio observacional, descriptivo y prospectivo para caracterizar a 200 pacientes diabéticos de tipo 2, diagnosticados con complicaciones vasculares y riesgo de ateroesclerosis, los cuales fueron ingresados en el Servicio de Medicina Interna del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba, desde junio del 2010 hasta igual mes del 2011. Entre las complicaciones más frecuentes figuraron: enfermedades cardiovasculares (29,5 %, neuropatía (21,5 % y retinopatía (19,5 %. Prevalecieron los afectados con 3 complicaciones (40,5 %, los que tenían un tiempo de evolución de la enfermedad de 11-15 años (38,0 %; además de la hiperlipidemia (35,0 %, la hipertensión arterial (32,0 % y el tabaquismo (26,5 % como factores de riesgo. Se concluye que con un enfoque multidisciplinario en el tratamiento y control de esta enfermedad se logra mejorar el pronóstico de los afectados.

  11. Characterization of potassic materials of Pocos de Caldas alkaline massif, Southeastern Brazil; Caracterizacao de materiais potassicos do macico alcalino de Pocos de Caldas (MG)

    Energy Technology Data Exchange (ETDEWEB)

    Goncalves, P.; Navarro, F.C.; Roveri, C.D. [Universidade Federal de Alfenas (UNIFAL), MG (Brazil); Bergerman, M.G., E-mail: pattypgpatty@gmail.com [Universidade de Sao Paulo (USP), SP (Brazil)

    2016-07-01

    Potassium, which has featured in Brazil's agricultural sector and in the world's in the application of fertilizers, is present in magmatic rocks, such as nepheline syenite and phonolite, found in the Alkaline Massif of Pocos de Caldas (AMPC). The rare earth elements (REE), in turn, also occur in this region and have important uses in various industrial fields. The aim of this study was to investigate the potential of potassic rocks of AMPC in the fertilizer and rare earths industry. Five samples were collected and characterized. It was observed that there was no preferential concentration by granulometric range of potassium oxide, alumina, silica and iron oxide. Feldspathic mass, potash feldspar, and muscovite were found in all samples. The samples show REE with amounts greater than those found in the earth's crust, except for lutetium and scandium and possessed average content of potassium oxide from 8.70 to 14.40%. (author)

  12. PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases.

    Directory of Open Access Journals (Sweden)

    Marzieh Ayati

    2016-11-01

    Full Text Available Susceptibility loci identified by GWAS generally account for a limited fraction of heritability. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limited practical use. Many methods have been developed to overcome these limitations by incorporating prior biological knowledge. However, most of the information utilized by these methods is at the level of genes, limiting analyses to variants that are in or proximate to coding regions. We propose a new method that integrates protein protein interaction (PPI as well as expression quantitative trait loci (eQTL data to identify sets of functionally related loci that are collectively associated with a trait of interest. We call such sets of loci "population covering locus sets" (PoCos. The contributions of the proposed approach are three-fold: 1 We consider all possible genotype models for each locus, thereby enabling identification of combinatorial relationships between multiple loci. 2 We develop a framework for the integration of PPI and eQTL into a heterogenous network model, enabling efficient identification of functionally related variants that are associated with the disease. 3 We develop a novel method to integrate the genotypes of multiple loci in a PoCo into a representative genotype to be used in risk assessment. We test the proposed framework in the context of risk assessment for seven complex diseases, type 1 diabetes (T1D, type 2 diabetes (T2D, psoriasis (PS, bipolar disorder (BD, coronary artery disease (CAD, hypertension (HT, and multiple sclerosis (MS. Our results show that the proposed method significantly outperforms individual variant based risk assessment models as well as the state-of-the-art polygenic score. We also show that incorporation of eQTL data improves the performance of identified POCOs in risk assessment. We also assess the biological relevance of PoCos for three diseases that have similar biological mechanisms

  13. Condición laboral asociada a complicaciones en el embarazo en noreste de México

    Directory of Open Access Journals (Sweden)

    Edgar Taboada Aguirre

    2014-12-01

    Full Text Available Introducción: Las complicaciones clínicas en el embarazo son predictores importantes para la mortalidad materna y desenlace del embarazo dependiendo de la atención que reciban las mujeres en este periodo trascendental de la vida. Algunos de los determinantes asociados con el problema están ligados a la situación laboral y la ocupación de la madre durante el embarazo. Material y métodos: Se realizó un estudio transversal en el año 2012, en la Unidad de Medicina Familiar # 43 del Instituto Mexicano del Seguro Social. Se realizó un muestreo aleatorio de un total de 2314 se seleccionaron 318 mujeres que accedieron a participar. El objetivo principal del estudio de analizar la asociación del estatus laboral con las complicaciones durante la gestación (definidas como cualquier paciente que durante la gestación haya padecido preeclampsia, eclampsia, amenaza de aborto, amenaza de parto prematuro, infección de vías urinarias se incluyeron además variables sociodemográficas conocidas por su relación con las complicaciones prenatales. Resultados: La media de la edad fue de 26 años. La media del índice de masa corporal fue de 27. Las mujeres trabajadoras presentaron una probabilidad 64 % más alta que las no trabajadoras de presentar complicaciones en el embarazo (OR=1.64; IC95 %: 1.04-2.58. La infección de vías urinarias en las mujeres trabajadoras fue un 75 % más probable (OR=1.75; IC 95 %: 1.12-2.73, las mujeres trabajadoras tuvieron 2.72 veces más probabilidad de padecer una amenaza de aborto que las no trabajadoras (OR=2.72; IC 95 %:1.36-5.45, las trabajadoras tuvieron 2.20 veces mayor probabilidad de padecer amenaza de parto prematuro que las no trabajadoras (OR=2.20; IC 95 %: 0.91-5.29. Además las trabajadoras tuvieron una probabilidad 96 % más alta de que su embarazo terminara en cesárea (OR=1.96; IC 95 %:1.25-3.07. Conclusiones: Los resultados sugieren que la actividad laboral es un factor importante para la presentaci

  14. Síntomas y complicaciones posfunduplicatura: abordaje diagnóstico y tratamiento

    Directory of Open Access Journals (Sweden)

    S. Sobrino-Cossío

    2017-07-01

    Full Text Available En la actualidad la funduplicatura laparoscópica tipo Nissen se considera el tratamiento quirúrgico de elección para la enfermedad por reflujo gastroesofágico (ERGE y su efectividad a largo plazo es mayor del 90%. Dentro de los factores predictores de buena respuesta clínica están la adecuada selección del paciente y la experiencia del cirujano. Sin embargo, la prevalencia de síntomas nuevos, persistentes y recurrentes posteriores al procedimiento antirreflujo puede ser de hasta un 30%. Las causas son múltiples pero en general se deben a una o más alteraciones en la anatomía y en la función esofagogástrica. Ante la persistencia de los síntomas posterior al procedimiento quirúrgico se debería de utilizar el término «falla». En el caso de que un paciente inicialmente manifieste control de sus síntomas y posteriormente estos reaparezcan, se pudiera emplear el término «disfunción». Por otra parte, ante el empeoramiento de los síntomas o la aparición de síntomas o situaciones clínicas que no existían antes de la cirugía, debe de considerarse una «complicación». La disfagia postoperatoria y los síntomas dispépticos son muy frecuentes y requieren un abordaje integral para poder determinar el mejor tratamiento posible. En esta revisión se detallan los aspectos fisiopatológicos, de diagnóstico y tratamiento de los síntomas y las complicaciones posteriores a la funduplicatura para el manejo de la ERGE.

  15. La edad materna avanzada como elemento favorecedor de complicaciones obstétricas y del nacimiento

    Directory of Open Access Journals (Sweden)

    Jorge Manuel Balestena Sánchez

    2015-10-01

    Full Text Available Introducción: el aumento actual del embarazo en mujeres añosas provoca un riesgo superior para la mujer y su feto. Objetivo: evaluar la edad materna avanzada como factor de complicaciones obstétricas y del nacimiento. Material y método: se efectuó una investigación observacional, retrospectiva, transversal y analítica en el Hospital General Docente "Abel Santamaría Cuadrado" de Pinar del Río entre 2012 y 2013. El universo de estudio fueron la totalidad de gestantes que ingresaron en el período estudiado. La muestra se formó con gestantes añosas (grupo estudio 360 pacientes y un grupo control (720 pacientes con embarazadas entre 25 y 30 años; ambos se escogieron por muestreo intencionado. Se resumieron las variables cualitativas mediante frecuencias absolutas y relativas porcentuales. Se utilizaron las pruebas de ji cuadrado, Odd Ratio. El intervalo de confianza para el Odd Ratio al 95%. Resultados: hubo un predominio de la embarazada con partos anteriores (92.8%, la normopeso (68.9%, el 34.4% padecían alguna enfermedad crónica, siendo la principal la hipertensión arterial; la anemia durante el embarazo estuvo presente en el 34.4%, el 88.3% parieron a término, de modo espontáneo; además preponderó la cesárea con un (52.2%. La morbilidad intraparto se manifestó en el 13.1%, mientras la puerperal en el 26.7%. Hubo una elevada asociación del embarazo prolongado con la enfermedad hipertensiva, el oligoamnios y la anemia (p < 0,001, también con la inducción del parto (p < 0,001 y la cesárea (p < 0,001, así como con la morbilidad puerperal (p < 0,001. Conclusiones: la edad materna avanzada es un factor de riesgo a tener en cuenta durante el proceso de la gestación y el nacimiento.

  16. Geology and Geochemistry of the Poco de Fora region-Curaca river valley-Bahia-Brazil

    International Nuclear Information System (INIS)

    Figueiredo, M.C.H. de.

    1976-01-01

    In the Poco de Fora region level rocks of light metamorphism, from Caraiba group, corresponding to: - a meta-sedimentar sequence from Lower Pre-cambrian (Archean) - maphic-ultramaphic bodies with Fe and Cu sulphides of volcanogenic origin, and - sienitic ortho-gneiss. Geological, petrographic, geochemistry and geochronological studies were done. The sienitic-intrusion, from the upper crust, occur during the Archean-beginning of the Proterozoic. All the region was re-mobilized, and the sienitic was metamorphosed during Transamazonic Orogeny (2.200 to 1.800 m.y.). (C.D.G.) [pt

  17. Distribution of radioactive anomalies at Morro do Ferro hill in Pocos de Caldas Alkaline Complex, MG

    International Nuclear Information System (INIS)

    Fujimori, K.

    1980-10-01

    Sistematic radiation intensity measurements were alone at Morro do Ferro hill in the Pocos de Caldas Alkaline Complex, using portable Scintrex spectrometer for U, Th, K and total counting (TC). Complementary geochemical analyses were alone on selected 26 samples. It was observed that there are many radiation focii in that place and they are oriented in the E-W direction. The geochemical analyses show that Uranium has participated also in the inicial mineralization of radioactive elements. The contribution of 238 U series daugher elements is relatively strong although Uranium was 'washed' by leaching. (Author) [pt

  18. Uranium ore from Morro do Agostinho, Pocos de Caldas, Minas Gerais, Brazil

    International Nuclear Information System (INIS)

    Matsuda, H.T.

    1976-01-01

    Three non-destrutive methods for determination of uranium from Morro do Agostinho's ore, Pocos de Caldas, Minas Gerais are presented. Comparative data between chemical analysis (volumetric method) and cited non-destructive methods are shown. Gamma spectrometry, x-rays fluorescense and delayed neutrons counting are the methods discussed. Uranium's and molibdenium's behavior related to anionic sulphuric resin system is also discussed. Comparative studies concerning retention of uranium and molibdenium in strong and weak anionic resins as well as selective elution using appropriate solvents are shown [pt

  19. Complicaciones en el uso del colgajo TRAM pediculado para reconstrucción mamaria por cáncer

    Directory of Open Access Journals (Sweden)

    J.L. López-Robles

    2013-12-01

    Full Text Available Las opciones en reconstrucción mamaria tras tratamiento oncoquirúrgico incluyen el uso de técnicas con implantes, el uso de colgajos autólogos y la combinación de ambos métodos. A nivel internacional, la reconstrucción con tejidos autólogos es el estándar de oro para la reconstrucción mamaria y específicamente, la utilización del colgajo miocutáneo de recto abdominal (colgajo TRAM pediculado es una de las opciones más empleadas. El presente estudio define con qué frecuencia se presentaron complicaciones tras la cirugía con colgajo TRAM pediculado para reconstrucción mamaria por cáncer en el Servicio de Cirugía Plástica y Reconstructiva del Hospital Central Sur de Alta Especialidad (PEMEX de la Cuidad de México (México, en un periodo de estudio de 7 años. Además, se identifican los factores de riesgo que influyeron sobre la aparición de dichas complicaciones. Diseñamos un estudio descriptivo, observacional y retrospectivo, que incluyó a 71 pacientes, de las cuales el 59.15 % presentaron alguna complicación. La mayoría de dichas complicaciones fueron menores (54.9 % y tan solo 3 pacientes presentaron alguna complicación mayor (4.2 %. La complicación del sitio donante del colgajo más frecuente fue la aparición de hernia abdominal (9.86 %. La complicación más frecuente del colgajo y del sitio receptor fue la necrosis grasa parcial (23.94 %. Las únicas complicaciones sistémicas fueron atelectasia y tromboembolismo pulmonar, con 1 caso de cada. En el análisis bivariado, las pacientes fumadoras tuvieron un 40 % más riesgo de presentar una complicación del colgajo en comparación con las no fumadoras (p=0.041. Las pacientes sometidas a radioterapia tuvieron un incremento del 30 % en las complicaciones totales en comparación con las no radiadas (p=0.021. Al comparar el hecho de recibir quimioterapia o no y la presencia de necrosis grasa, el 32 % de las pacientes tuvo esta complicación en comparación con el 10

  20. Edad, aprendizaje, tiempo quirúrgico y complicaciones en la cirugía videolaparoscópica

    Directory of Open Access Journals (Sweden)

    Luis Miguel Pita Armenteros

    1999-12-01

    Full Text Available El tiempo quirúrgico es un factor de riesgo menos importante en las operaciones electivas, mucho menos si existe gentileza quirúrgica y control anestésico. El método videolaparoscópico exige de mayor monitoreo en la anestesia y es de mínimo traumatismo. Sin embargo, se habla de tiempos quirúrgicos muy elevados en la fase de aprendizaje como limitante en la productividad quirúrgica con aumento del costo quirófano y de complicaciones, en particular en cirujanos mayores. Este trabajo desmitifica edad, aprendizaje, tiempo quirúrgico y complicaciones en la cirugía videolaparoscópica. La prudencia influye en el tiempo quirúrgico, pero disminuye conversión y complicaciones. Obtener la calificación básica en cirugía videolaparoscópica requiere de 40 a 50 operacionesSurgical time is not very significant risk factor in elective surgery. It is much less important when there is an adequate surgical management and anesthetic control. The videolaparoscopic method demands a greater anesthetic monitoring and produces minimun traumatism. However, reference is made to extremely elevated surgical times during training that limit surgical productivity and increase the cost of the operation and the number of complications particularly among major surgeons. This paper considers age, training, surgical time and complications in videolaparoscopic surgery. Prudence influences on the surgical time but reduces conversion and complications. To obtain the basic qualification in videolaparoscopic surgery, it is necessary to perform 40 or 50 operations

  1. Condición laboral asociada a complicaciones en el embarazo en noreste de México

    OpenAIRE

    Edgar Taboada Aguirre; Eduardo Manzanera Balderas; Maria Mercedes Dávalos Torres

    2014-01-01

    Introducción: Las complicaciones clínicas en el embarazo son predictores importantes para la mortalidad materna y desenlace del embarazo dependiendo de la atención que reciban las mujeres en este periodo trascendental de la vida. Algunos de los determinantes asociados con el problema están ligados a la situación laboral y la ocupación de la madre durante el embarazo. Material y métodos: Se realizó un estudio transversal en el año 2012, en la Unidad de Medicina Familiar # 43 del Instituto Mexi...

  2. Factores causales en las complicaciones de estomas intestinales en cirugía de emergencia. Hospital Luis Vernaza, 2013.

    OpenAIRE

    Morán Mancero, María Cristina

    2014-01-01

    El estoma intestinal es una apertura del intestino en la superficie del abdomen. Las estadísticas según diversos autores indica que hay aproximadamente unas 32.000 personas ostomizadas, de las cuales el 75% presentan una colostomía y el 10% una ileostomía. Objetivo:Determinar los factores causales en las complicaciones tempranas y tardías de los estomas intestinales en la cirugía de emergencia.Metodología:Estudio de tipo Retrospectivo, Observacional, Transversal, de nivel Descriptivo y diseño...

  3. Normal tissue complications after radiation therapy Las complicaciones de la radioterapia en los tejidos sanos

    Directory of Open Access Journals (Sweden)

    Jolyon H. Hendry

    2006-09-01

    desarrollo. Asimismo, se describen las bases biológicas del período de latencia que precede a la aparición de las complicaciones tisulares; la relación entre la dosis de radiación y la incidencia de complicaciones; las consecuencias de aumentar el volumen irradiado; las reacciones tisulares tempranas y tardías; los efectos de cambios en el fraccionamiento de las dosis y en las tasas de dosis; y las reacciones observadas al aplicar una combinación de quimioterapia y radioterapia. Se ofrecen ejemplos de nuevos conocimientos en el campo de la radiobiología clínica que se han adquirido mediante ensayos con nuevos protocolos. Entre las posibles modificaciones de los tratamientos figura el uso de modificadores de la respuesta biológica; en el futuro próximo, podría contarse también con modificaciones de los tratamientos para poder "predecir la respuesta". Por último, las dosis cuya eficacia biológica está demostrada y que están prescritas para tratar el cáncer cervicouterino usando una combinación de braquiterapia y teleterapia son menores en algunos centros que en otros, como se explica en este trabajo. El asunto debe examinarse más a fondo. Una gran abundancia de datos de carácter preclínico y clínico ha permitido comprender mucho mejor las bases biológicas de la radioterapia, y ello a su vez ha llevado a una serie de innovaciones en este campo, tanto en forma de estrategias físicas como biológicas. También es importante prestar atención al tratamiento de una gran variedad de cánceres en países en desarrollo, para los cuales continuamente se elaboran protocolos terapéuticos eficaces orientados a ahorrar recursos. Debería adoptarse en todas partes un único sistema de puntuación para documentar los efectos nocivos de la radioterapia. Asimismo, la toxicidad tardía debería ser un parámetro clínico de valoración obligatoria y figurar en las estadísticas de los resultados del tratamiento.

  4. Niveles de verbalización y resolución colaborativa de problemas poco estructurados

    Directory of Open Access Journals (Sweden)

    José D. Chávez

    2015-01-01

    Full Text Available Se describieron las verbalizaciones de seis estudian - tes universitarios que resolvieron colaborativamen - te un problema poco estructurado. Partiendo de que aportaban información sobre la regulación metacog - nitiva y la solución de problemas, las verbalizacio - nes fueron categorizadas en niveles. Se utilizaron matrices espacio estado para interpretar los niveles de verbalización y los procesos de resolución de problemas poco estructurados. Se evidenció el predo - minio de verbalizaciones no reguladas, la ausencia de verbalizaciones relacionadas a la elaboración de justificaciones y la superficialidad del monitoreo y la evaluación. La evidencia apoya la idea de que la interacción entre pares no mejora por sí misma la solución de problemas. Los resultados invitan al diseño de situaciones de resolución de problemas que efectivamente promuevan la regulación meta - cognitiva entre pares.

  5. Ore reserve evalution, through geostatistical methods, in sector C-09, Pocos de Caldas, MG-Brazil

    International Nuclear Information System (INIS)

    Guerra, P.A.G.; Censi, A.C.; Marques, J.P.M.; Huijbregts, Ch.

    1978-01-01

    In sector C-09, Pocos de Caldas in the state of Minas Gerais, geostatistical techniques have been used to evaluate the tonnage of U 3 O 8 and associated minerals and to delimit ore from sterile areas. The calculation of reserve was based on borehole information including the results of chemical and/or radiometric analysis. Two-and three dimensional evalutions were made following the existing geological models. Initially, the evaluation was based on chemical analysis using the more classical geostatistical technique of kriging. This was followed by a second evaluation using the more recent technique of co-kriging which permited the incorporation of radiometric information in the calculations. The correlation between ore grade and radiometric was studied using the method of cross-covariance. Following restrictions imposed by mining considerations, a probabilistic selection was made of blocks of appropriate dimensions so as to evaluate the grade tonnage curve for each panel. (Author) [pt

  6. Evaluation of NORM concentration in water treatment of Pocos de Caldas municipality, MG, Brazil: preliminary results

    International Nuclear Information System (INIS)

    Ferreira, Adriano Mota; Villegas, Raul A.S.; Fukuma, Henrique Takuji

    2014-01-01

    NORM is the acronym used to refer to naturally occurring radioactive materials. Besides being objects of study and monitoring such materials can be used as raw material or as by-products or waste of industrial activities. Oil and gas, mining and water treatment are examples of facilities that can handle NORM. In such cases, their concentration at significant levels from the perspective of environmental and occupational radiation protection may occur. This study aims to evaluate the presence of the natural radioactive 238 U and 232 Th series in the treatment of city water elements Pocos de Caldas - MG (water, materials and waste). The study can serve as an indication of the necessity of a more detailed review in the locally and in the country on this radiological issue. (author)

  7. Isotope disequilibria 4n series in the Morro do Ferro System, Pocos de Caldas (MG)

    International Nuclear Information System (INIS)

    Bonotto, D.M.; Fujimori, K.

    1986-01-01

    Thorium isotopic analyses were performed on well spoils of the main ore body at Morro do Ferro, Pocos de Caldas (MG), on groundwaters from several boreholes in the area and surface waters from a stream that originates at the base of the hill. For extraction of thorium a long chemical process was applied to samples; activities of Th-228 and Th-232 isotopes (4n series) were determined by alpha spectrometry method. The rations Th-228/Th-232 determined for well spoils did not show marked disequilibria between these isotopes. In ground and surface waters, the ratios Th-228/Th-232 showed marked isotopic fractionation between these nuclides, not related to selective leaching of Th-228 in relation to Th-232 or recoil of Th-228 nucleons. (author) [pt

  8. Characterization of potassic materials of Pocos de Caldas alkaline massif, Southeastern Brazil

    International Nuclear Information System (INIS)

    Goncalves, P.; Navarro, F.C.; Roveri, C.D.; Bergerman, M.G.

    2016-01-01

    Potassium, which has featured in Brazil's agricultural sector and in the world's in the application of fertilizers, is present in magmatic rocks, such as nepheline syenite and phonolite, found in the Alkaline Massif of Pocos de Caldas (AMPC). The rare earth elements (REE), in turn, also occur in this region and have important uses in various industrial fields. The aim of this study was to investigate the potential of potassic rocks of AMPC in the fertilizer and rare earths industry. Five samples were collected and characterized. It was observed that there was no preferential concentration by granulometric range of potassium oxide, alumina, silica and iron oxide. Feldspathic mass, potash feldspar, and muscovite were found in all samples. The samples show REE with amounts greater than those found in the earth's crust, except for lutetium and scandium and possessed average content of potassium oxide from 8.70 to 14.40%. (author)

  9. Ra-226 collective dosimetry for surface waters in the uranium mining region of Pocos de Caldas

    International Nuclear Information System (INIS)

    Paschoa, A.S.; Sigaud, G.M.; Montenegro, E.C.; Baptista, G.B.

    1980-01-01

    Graphs of the collective dose equivalent for the whole body, bone, gastro-intestinal tract (lower large intestine), kidneys, and liver, via the pathways of drinking water and ingestion of food grown in irrigated fields are presented as a function of the 226 Ra concentrations in the surface waters of the Pocos de Caldas region. The collective dose equivalent calculated from the 226 Ra concentrations measured in the baseline studies are compared with those collective dose equivalent estimated from the projected higher 226 Ra concentrations in the river waters. The 226 Ra concentrations in river waters of the region are expected to be enhanced due to 226 Ra releases from uranium mining and milling operations. The dose equivalent commitment for the exposed population for the referred pathways is also estimated for the contribution of the mine during its predicted time of operation. The assumptions for the dose calculations are presented and the results obtained are discussed. (H.K.)

  10. Modelling of redox front and uranium movement in a uranium mine at Pocos de Caldas, Brazil

    International Nuclear Information System (INIS)

    Cross, J.E.; Gabriel, D.S.; Haworth, A.; Sharland, S.M.; Tweed, C.J.

    1991-04-01

    A study of the migration of uranium at the Pocos de Caldas uranium mine in Brazil under the influence of the infiltration of oxidising groundwaters has been performed. The modelling was carried out using the coupled chemical equilibria/transport code CHEQMATE. The work presented in this paper extends a previous study. Results give some encouraging agreements with field data, generally increasing confidence in the use of such modelling techniques in problems associated with the migration of radionuclides away from a nuclear waste repository. For particular aspects of the problem where good agreement with field data was not obtained, a number of reasons have been suggested. This study also highlights the importance of accurate thermodynamic data and choice of solubility-limiting mineral phases for modelling such systems. (author)

  11. Distribution of uranium, thorium and potassium in the alkaline rocks of Pocos de Caldas massif

    International Nuclear Information System (INIS)

    Rocha, E.B.

    1985-01-01

    The Pocos de Caldas massif, with area about 800 Km 2 , represents the greatest complex of alkaline rocks existent in the American continent. Although values of U and Th are well Known in the mineralized areas, few has been registered with respect to the distribution of those elements outside the ore deposits. The rocks of the massif, in general, present high contents of U and Th when confronted with the surrouding country rocks. The distribution of the U and Th appoint a relevant additional data in the discussion on the hypothesis of nepheline syenites bodies formation in Pocos de Caldas by crystal fractionation processes. In this work are provided results of the U, Th and K distribution in the main petrographic facies occurring in the several studies places of the massif, yielded by gamma-ray spectrometric analysis of the samples. Those analysis disclose that khibinites present average values about 38 ppm U and 120 ppm Th; lujavrites, about 14 ppm U and more than 70 ppm Th; U-Th depleted nepheline synites, about 12 ppm U and 38 ppm Th, Th/U ratios are close to 3,0 in the nepheline syenites, about 3,7 in the phonolites, reaching values close to 4,0 in the khibinites. These values are comparable with others Th/U ratios of selected series of alkaline rocks reported in the international literature. Uranium and Th comparative data, attained by delayed neutron counting activation analysis also are given. The results obtained for the fluorimetric analysis show loss of U leaching is greater in the fine-grained rocks (phonolites) than coarse-grained ones (lujavrites, Khibinites). The autoradiographic studies reveal that radioactive elements are found concentrated in mineral phases. A new assessment of the radiogenic heat production it is also available. (Author) [pt

  12. Ausentismo y complicaciones de salud en usuarios de programas de hipertensión arterial de Santa Marta (Colombia

    Directory of Open Access Journals (Sweden)

    Brigith Sánchez Serrano

    2017-01-01

    Full Text Available Objetivo:Identificar los factores presentes y las complicaciones de pacientes inscritos en losprogramas de hipertensión arterial de ocho centros ambulatorios de Santa Marta.Metodología:Estudio descriptivo, ambispectivo y multicéntrico; población conformada por24 programas de prevención y control de hipertensión arterial, seleccionados aleatoriamenteocho de ellos (30 %. De los 750 casos de inasistentes se calculó un tamaño muestral de 254,valor elevado a 300 para reducir el error de estimación. La información se recolectó medianteun cuestionario de identificación de condiciones de habilitación de programas, base de datos deinasistentes y aplicación de entrevista semiestructurada.Resultados:El porcentaje de incumplimiento de las condiciones de los programas de hipertensiónfue de (9 %; el récord de ausentismo de pacientes inscritos fue de 35,62 %. Mientras que losprincipales factores que motivaron el ausentismo fueron de orden institucional (32,6 %, personal(26,3 %, socioeconómicos (8.5 %, otras alternativas de tratamiento (9,4 %; las complicacionesmanifestadas sobresalientes se relacionaron con angina de pecho (34,1 %, alteraciones renales(29,2 % e infartos (9.7 %.Conclusiones:A pesar de los esfuerzos que llevan a cabo los organismos de salud para laprevención y el control de la hipertensión, aún es necesario desarrollar nuevas estrategias quereduzca el índice de ausentismo de los pacientes inscritos a dichos programas, y de esa maneracontribuir positivamente en la reducción de las tasas de complicaciones en la salud.

  13. Complicaciones de los accesos vasculares centrales en los recién nacidos del Instituto Nacional de Perinatología

    Directory of Open Access Journals (Sweden)

    S. Carrera Muiños

    2016-10-01

    Conclusión La incidencia de complicaciones relacionadas con el catéter continúa siendo un problema en todas las unidades de cuidados intensivos neonatales; la sepsis en particular es la principal complicación y la que mayor impacto tiene sobre la morbimortalidad neonatal.

  14. Sífilis una enfermedad que puede producir serias complicaciones en el organismo y producir la muerte. Puede detectarse a tiempo y tiene cura

    OpenAIRE

    Portilla, José Luis

    2009-01-01

    La sífilis es una ETS que puede causar complicaciones a largo plazo o la muerte, si no se trata de manera adecuada. Los síntomas en los adultos se dividen en fases. Estas fases son sífilis primaria, secundaria, latente y avanzada.

  15. It's not business as usual anymore

    International Nuclear Information System (INIS)

    Brown, C.W. Jr.

    1992-01-01

    In 20 years, a complex body of environmental laws, regulations, and decisions has been established in the U.S. Basic knowledge of environmental laws, regulations, and management techniques is now necessary for design, construction, and operation of oil field facilities. Environmental permits are on the critical path and could significantly affect project viability or the cost of doing business. In California and many other states, resource development projects face complex and voluminous environmental regulations. Because of these permitting obstacles and the competition for the available permits, early environmental planning is necessary if a project is to be successful and if costs and future liabilities are to be minimized. This paper reviews eight federal environmental laws, significant events that affect our daily business, and the reasons why environmental management must be integrated in our business as usual work decisions to minimize future (hidden) liabilities

  16. It's not business as usual - anymore

    International Nuclear Information System (INIS)

    Brown, C.W.

    1991-01-01

    In a short period of 20 years, a complex body of environmental laws, regulations, and decisions has been established in the United States. Basic knowledge of environmental laws, regulations, and environmental management are now necessary for design, construction, and operation of our oil field facilities. environmental permits are on the critical path and could have the potential to significantly affect project viability or the cost of doing business. In California and many other States, resource development projects faced complex and voluminous environmental regulations. These permitting obstacles along with competition for the available permits require early project environmental planning if a project is to be successful and if costs and future liability are to be minimized. This paper will review eight Federal environmental laws, significant events that affect our daily business, and why environmental management must be integrated in our business as usual work decisions to minimize future (hidden) liabilities

  17. Characterization of Rn-222 production in Campo do Cercado C/09 Pocos de Caldas, Minas Gerais State

    International Nuclear Information System (INIS)

    Pereira, E.B.

    1977-01-01

    A systematic study for correlating the Rn-222 escape with the main geochemical and mineralogical factors for understanding of some change processes from uranium deposits in Campo do Cercado C-09 in Pocos de Caldas, Minas Gerais State is described. (author)

  18. Developed methodology for the geologic control of the secondary uranium concentrations in Osamu Utsumi, Pocos de Caldas (MG)

    International Nuclear Information System (INIS)

    Magno Junior, L.B.

    1982-01-01

    It was developed a methodology for the geologic control of the mining of the secondary uranium concentrations in the Osamu Utsumi mine, Pocos de Caldas. A sequential systematization with the definitions and objectives of the operational phases of the mining explotation is shown, in addition of a scheme and flow charts of them. (A.B.) [pt

  19. Manifestaciones clínicas y complicaciones de la fase aguda de bartonelosis o Fiebre de la Oroya en pacientes atendidos en el Hospital Nacional Cayetano Heredia.

    Directory of Open Access Journals (Sweden)

    Ciro Peregrino Maguiña Vargas

    2008-07-01

    Full Text Available Objetivos: Determinar las características clínicas, epidemiológicas y de laboratorio de la bartonelosis aguda, así como las complicaciones en una serie de pacientes atendidos en el Hospital Nacional Cayetano Heredia. Material y métodos: Estudio descriptivo de tipo serie de casos de pacientes mayores de 15 años con bartonelosis aguda hospitalizados en el Hospital Nacional Cayetano Heredia entre 1993 y 2006. Resultados: La edad promedio fue 27,8 años, 72,7% fueron varones, 51,5% procedía de Lima y 33,3% de Ancash. Los síntomas principales fueron: fiebre 90,9%, cefalea 87,9%, hiporexia 75,5%, baja de peso 63,6%, e ictericia 57,6%. Dos pacientes presentaron alteraciones en el fondo de ojo: retinitis exudativa y retinopatía hemorrágica. El hematocrito promedio fue 20,8% y 63,6% cursaron hematocrito £20%. Hubo desviación izquierda en 24,2%, hiperbilirrubinemia a predominio indirecto 62,5% e hipoalbuminemia (< 3mg/dl 56,5%. Se presentaron complicaciones en 84,8%, el 27,2% requirió internamiento en UCI. Las complicaciones no infecciosas ocurrieron en 84,8%, hematológicas 81,8% y gastrointestinales 78,7%. Las complicaciones infecciosas se presentaron en 12,1%. Los antibióticos más utilizados fueron ciprofloxacina 66,6% y cloranfenicol 42,4%, se administró corticoides en 9,1% y se transfundió paquete globular en 42,4%. Conclusiones: Los pacientes de UCI tuvieron más complicaciones cardiovasculares, trombocitopenia y mayor severidad de la anemia. No se registró mortalidad. (Rev. Med Hered 2008;19:87-95

  20. Fourth natural analogue working group meeting and Pocos de Caldas project final workshop

    International Nuclear Information System (INIS)

    Come, B.; Chapman, N.A.

    1991-01-01

    The fourth meeting of the CEC-sponsored natural analogue working group (NAWG) was held in Pitlochry, Scotland, from 18 to 22 June 1990, and also included the final workshop of the Pocos de Caldas (Brazil) natural analogue project, sponsored by Nagra (CH), SKB (S) UK-DOE and US-DOE. About 80 specialists attended this meeting, originating from EC Member States and also Australia, Brazil, Canada, Finland, Japan, Sweden, Switzerland and the USA. The IAEA and OCDE-NEA were also represented. This plenary meeting was the opportunity to review and discuss five years of progress and activities of natural analogues in central areas of performance assessment: waste forms and engineered barriers, geochemistry and radionuclide speciation, radionuclide migration and the overall geological context of radwaste disposal. In addition, a feedback session provided the opportunity for regulators and those individuals who had advisory roles to give their views and impressions on the significance of natural analogue research. These proceedings, divided into two sessions, contain 32 technical papers and 14 abstracts of published papers

  1. Transfer of radon-222 from rocks of the Pocos de Caldas plateau to the waters

    International Nuclear Information System (INIS)

    Bonotto, Daniel Marcos; Lima, Jorge Luis Nepomuceno de

    1997-01-01

    The analytical procedures developed at the Sector of Unstable Isotopes of the Laboratory of Geochemistry, which belongs to the Department of Petrology and Metallogeny located at the Institute of Geosciences and Exact Sciences - Universidade Estadual Paulista Julio de Mesquita Filho (UNESP) to measure the release of 222 Rn from rocks to the waters is described. The methodology established was used to evaluate the emanation coefficient of 222 Rn from experiments of water-rock interaction under controlled conditions in the laboratory, which is an important parameter necessary to interpret the radioactivity related to dissolved 222 Rn content in waters. Four typical rocks from Pocos de Caldas Plateau were sampled for the experiments: phonolite, nepheline syenite, pseudoleucite tinguaite and silicified sandstone. The 226 Ra content of these rocks was evaluated by gamma-ray spectrometry using a Nal(TI) scintillation detector, a method that has been currently utilized in nuclear geophysics or isotope geochemistry to measure the equivalent uranium (e U). The 226 Ra content in the studied rocks and the 222 Rn transferred to the waters due to its generation by its 226 Ra progenitor allowed an estimation of the emanation coefficient of 222 Rn. A preliminary investigation on the influence of the mass of the rock in contact with water, of the surface area of the rock in contact with water and of the 226 Ra content in rocks on the amount of 222 Rn released to the water was also performed. (Author)

  2. Thorium - humic compound interaction in the water of Morro do Ferro (Pocos de Caldas, MG, Brazil)

    International Nuclear Information System (INIS)

    Kuechler, I.L.

    1986-01-01

    Experimental procedures and results are presented on the determination of thorium and organic dissolved carbon (DOC) in natural waters (bore hole and surface waters) from the Morro de Ferro, a thorium - rare earth occurrence situated in the Pocos de Caldas Plateau in Minas Gerais (Brazil). A positive correlation between Th-232 and humic compounds content was abserved. Utilizing ultrafiltration techniques with Amicon membranes (XM-300, PM-10, UM-10 and YM-2), organic compounds with molecular weights above 1000 units were separated and concentrated from waters. Percolation waters rich in organic material concentrate DOC and Th-232 in the high molecular weight fractions ( > 10.000 MW units). Humic acid was separated from a percolation water sample and characterized by elemental and infrared spectroscopic analysis. The distribution coefficient of Th-232 between water and sediment was shown to be inversely correlated to DOC concentration, as reported by other authors for different environments. These results were also confirmed by laboratory experiments, which indicated additionally that low concentrations of humic acid ( [pt

  3. Ground water chemical evolution of Pocos de Caldas - Minas Gerais State -Brazil

    International Nuclear Information System (INIS)

    Cruz, W.B.; Peixoto, C.A.M.

    1991-01-01

    The chemical evolution and the origin of the groundwater, cold and thermal springs composition are analysed related to the geochemical environment of the Pocos de Caldas alkaline complex. The thermal waters origin are related to a large and deep open fracture system in three main directions: N14E, N50E and E-W. The tritium content when simultaneously analysed with the deuterium and oxygen-18 set show that thermal waters are old meteoric waters (30-40 years of age). On the other hand, the cold springs that circulate on the superficial levels are more recent, which is a characteristic of an acid oxidizing environment without sulfides and greater concentration of free CO 2 and Rn 222 . The pH increases slowly with depth and also the H C O 3 - , Na + , SO 4 2- and the Si O 2 content. High concentrations of fluoride follow this process. Reducing environment with an increase in the sulphide content and a decrease in radioactivity are trends in the system studied. (author)

  4. Migration of radium from the thorium ore deposit of Morro do Ferro, Pocos de Caldas, Brazil

    International Nuclear Information System (INIS)

    Campos, M.J.; Penna-Franca, E.; Lobao, N.; Trindade, H.; Sachett, I.

    1986-01-01

    A large thorium ore deposit is located in Morro de Ferro, a hill in the Pocos de Caldas Plateau, Minas Gerais, Brazil, which contains an estimated 30 000 t of Th and 100 t of U in a highly weathered matrix exposed to erosion and leaching. 228 Ra and 226 Ra were analyzed in surface waters collected at various points in the drainage basin and in groundwaters from wells drilled through and around the ore body. The concentrations in groundwater demonstrated that radium is markedly leached by rainwater percolating through the ore body. In its transit underground, radium is removed from groundwater by sorption on soil particles and this natural process greatly reduces the radium discharged to the environment. In dry weather, the concentration of dissolved 228 Ra in the main stream draining the Morro do Ferro is 7.0+-1.1 mBq litre -1 and in a control stream 1.6+-0.3 mBq litre -1 . The estimated 228 Ra mobilization rate by solubilization is of the order of 10 -7 y -1 . (author)

  5. Effluent control for the uranium mine area at Pocos de Caldas, Brazil

    International Nuclear Information System (INIS)

    Rochedo, E.R.R.; Vasconcellos, L.M.H.

    2005-01-01

    Derived levels for effluents control for the Industrial Complex of Pocos de Caldas - CIPC, Brazil were set based on the IAEA recommendation for the dose assessment of critical groups. Although the industry has stopped the uranium extraction in 1988, the installation is kept under regulatory control, as it has not yet been decommissioned. A screening procedure was set to control the effluent releases from the three main areas, the open pit mine area, the tailings dam and the waste rock piles. To each one of these areas, the dose restriction of 0,3 mSv/a was adopted, since each effluent refers to a different critical group. Monthly-composed samples are collected weekly at each outflow and sent to IRD. The radionuclides analyzed are 238 U, 226 Ra, 210 Pb, 232 Th and 228 Ra. If the activity concentration for any of these nuclides surpasses the established reference level to that particular source, a complete dose assessment for the critical group is performed using the computer program, Monitor, built based on IAEA recommendations for dose assessment to critical groups. The results show that Brazilian regulations related to public exposure are being accomplished by the installation operation. It is pointed out the relevance of maintaining the current treatment to the acid drainages and effluents from the tailings dam, until the whole area is properly decommissioned. (author)

  6. Las voces limpio y poco en el habla sur Andina de Nariño, Colombia

    Directory of Open Access Journals (Sweden)

    Roberto Ramírez Bravo

    2015-11-01

    Full Text Available Este trabajo examina la dimensión sociolingü.stica del uso de las voces limpio y poco en el habla sur andina nariñense; describe las singularidades fonéticas, morfosintácticas, léxico-semánticas y pragmáticas de las voces en cuestión, en diferentes contextos comunicativos; explica la convencionalidad de las mismas, en estructuras lingü.sticas complejas y cotidianas. Para el logro de los propósitos, el estudio se apoya en la etnografía de la comunicación; en este sentido, la recolección de la información se lleva a efecto a través de la observación directa de conversaciones formales e informales y del diario de campo; se realizan grabaciones consentidas y anónimas en contextos de intercomunicación espontánea. Finalmente, se genera un conversatorio con los integrantes del Grupo de Investigación en Argumentación (GIA,2 con la intención de triangular los datos obtenidos y confrontar las estructuras sociolectales de los enunciados analizados.

  7. Usual Vitamin Intakes by Mexican Populations.

    Science.gov (United States)

    Pedroza-Tobías, Andrea; Hernández-Barrera, Lucía; López-Olmedo, Nancy; García-Guerra, Armando; Rodríguez-Ramírez, Sonia; Ramírez-Silva, Ivonne; Villalpando, Salvador; Carriquiry, Alicia; Rivera, Juan A

    2016-09-01

    In the past several years, the consumption of high-energy, nutrient-poor foods has increased globally. Dietary intake data collected by the National Health and Nutrition Survey (ENSANUT) 2012 provide information to assess the quality of the Mexican diet and to guide food and nutrition policy. The aim was to describe the usual intake and the prevalence of inadequate intakes of vitamins for the overall Mexican population and by subgroups defined by sex, age, region, urban or rural areas, and socioeconomic status (SES). ENSANUT 2012 is a cross-sectional probabilistic survey representative of the Mexican population. Dietary information was collected by using the 24-h recall automated multiple-pass method (n = 10,096) with a repeated measurement on a subsample (n = 889) to permit adjustment for intraindividual variability with the use of the Iowa State University method. Mean usual intakes and the prevalence of inadequate intakes of thiamin, riboflavin, niacin, folate, and vitamins A, D, E, C, B-6, and B-12 were calculated for children aged 1-4 y (CH1-4y), children aged 5-11 y (CH5-11y), adolescents aged 12-19 y, and adults aged ≥20 y. In all of the age groups, prevalences of inadequate intakes of vitamins D and E were the highest (77-99% of adults and adolescents and 53-95% of CH5-11y and CH1-4y) and those of folate and vitamin A were intermediate (47-70% of adults and adolescents, 15-23% of CH5-11y and 8-13% of CH1-4y), whereas those of thiamin, riboflavin, niacin, and vitamins B-6, B-12, and C were the lowest (0-37% of adults, 1-27% of adolescents, and 0-2.4% of CH5-11y and CH1-4y). With few exceptions, the highest prevalences of inadequate intakes for vitamins were observed in the poorest populations (rural South region and the lowest tertile of SES). The intake of vitamins among Mexicans is inadequate overall. Information collected by ENSANUT can help target food assistance programs and develop strategies to prevent vitamin deficiencies. © 2016 American Society

  8. Business as usual and nuclear power

    International Nuclear Information System (INIS)

    2000-01-01

    Energy and nuclear policy makers face many challenges as they evaluate options to ensure an adequate supply of electricity while pursuing environmental, economic and energy security goals. Many analysts suggest that nuclear's share of global energy supply could decrease in coming decades. If energy markets and national energy policies continue along 'business as usual' lines, what are the issues that arise? what are the consequences for the long-term availability of nuclear technology and expertise? This book identifies the issues in a series of papers presented at a recent meeting jointly organised by the International Energy Agency and the OECD Nuclear Energy Agency. Senior energy policy makers and industry executives from OECD Member countries contributed these analyses. They offer a realistic assessment of nuclear's potential contribution, and the major challenges awaiting nuclear energy and energy supply in general. For those seeking a review of the current issues facing nuclear power within the broad context of energy policy, this is an essential report. (authors)

  9. Geoengineering, Climate Harm, and Business as Usual

    Science.gov (United States)

    Jankunis, F. J.; Peacock, K.

    2014-12-01

    We define geoengineering (GE) as the intentional use of technology to change the planet's climate. Many people believe GE is different in kind rather than degree from any other organized activity in human history. In fact, humans caused changes in the planet's climate long before the industrial age, and all organisms engineer their environments directly or indirectly. The relevant difference between this cumulative and generally inadvertent activity and GE is the presence of intention. Now that science has revealed the extent to which humans can change the climate, however, even the continuance of Business as Usual (BAU) is, in effect, a form of intentional GE, albeit one that will cause significant climate harm, defined as effects such as sea level rise that will impact human well-being. But as with all forms of engineering, the devil is in the details: what forms of GE should be tried first? Some methods, such as large-scale afforestation, are low risk but have long-term payoffs; others, such as aerosol injection into the stratosphere, could help buy time in a warming crisis but have unknown side-effects and little long-term future. Climate change is a world-wide, inter-generational tragedy of the commons. Rational choice theory, the spatial and temporal extension of the problem, poorly fitted moral frameworks, and political maneuvering are all factors that inhibit solutions to the climate tragedy of the commons. The longer that such factors are allowed to dominate decision-making (or the lack thereof) the more likely it is that humanity will be forced to resort to riskier and more drastic forms of GE. We argue that this fact brings an additional measure of urgency to the search for ways to engineer the climate differently so as to avoid climate harm in the most lasting and least risky way.

  10. Amyloidogenic determinants are usually not buried

    Directory of Open Access Journals (Sweden)

    Karletidi Carolina-Maria

    2009-07-01

    Full Text Available Abstract Background Amyloidoses are a group of usually fatal diseases, probably caused by protein misfolding and subsequent aggregation into amyloid fibrillar deposits. The mechanisms involved in amyloid fibril formation are largely unknown and are the subject of current, intensive research. In an attempt to identify possible amyloidogenic regions in proteins for further experimental investigation, we have developed and present here a publicly available online tool that utilizes five different and independently published methods, to form a consensus prediction of amyloidogenic regions in proteins, using only protein primary structure data. Results It appears that the consensus prediction tool is slightly more objective than individual prediction methods alone and suggests several previously not identified amino acid stretches as potential amyloidogenic determinants, which (although several of them may be overpredictions require further experimental studies. The tool is available at: http://biophysics.biol.uoa.gr/AMYLPRED. Utilizing molecular graphics programs, like O and PyMOL, as well as the algorithm DSSP, it was found that nearly all experimentally verified amyloidogenic determinants (short peptide stretches favouring aggregation and subsequent amyloid formation, and several predicted, with the aid of the tool AMYLPRED, but not experimentally verified amyloidogenic determinants, are located on the surface of the relevant amyloidogenic proteins. This finding may be important in efforts directed towards inhibiting amyloid fibril formation. Conclusion The most significant result of this work is the observation that virtually all, to date, experimentally determined amyloidogenic determinants and the majority of predicted, but not yet experimentally verified short amyloidogenic stretches, lie 'exposed' on the surface of the relevant amyloidogenic proteins, and also several of them have the ability to act as conformational 'switches'. Experiments

  11. Determination of Geogenic Radon Potential (GEORP) in Pocos de Caldas - Brazil

    International Nuclear Information System (INIS)

    Santos, Marcelo T.; Silva, Nivaldo C.; Guerrero, Eder T.Z.; Navarro, Fabiano C.; Oliveira, Rodrigo J.

    2015-01-01

    The noble gas 222 Rn is a radioactive isotope of the element radon that can be found in atmospheric air, among others gases, at broad range of concentration. This isotope decays from 238 U series, which is normally found in soil and rocks, especially in fault zones and fractures, where uranium presents greater mobility. The atmospheric high concentration of this gas is frequently related to confined environments including dwellings and other buildings with low air ventilation rate. Inhalation of this gas is acknowledged by international agencies such as WHO, as the second leading cause of lung cancer, being the first among the non-smoker population. That is the reason why, some countries have defined their regions with high radon potential where it is justified the implementation of construction techniques to reduce indoor radon concentration. This paper uses the Geogenic Radon Potential (GEORP) approach aiming to identify radon prone areas in the urban zone of Pocos de Caldas - Brazil. GEORP encompasses simultaneous measurements of the soil gas permeability and radon soil gas concentration. This investigation was accomplished using RADON-JOK permeameter, a device specially developed for in situ soil gas permeability, and ALPHAGUARD, a professional radon monitor. A large variability was observed in both radon soil concentration and soil gas permeability. Some areas have presented low gas permeability due to clayey soil characteristics thus medium GEORP. The majority of the points in this paper have been identified with high radon soil gas concentration showing values that reached 1,000 kBq.m -3 and presenting high radon index. (author)

  12. Determination of Geogenic Radon Potential (GEORP) in Pocos de Caldas - Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Marcelo T.; Silva, Nivaldo C.; Guerrero, Eder T.Z., E-mail: apoc@cnen.gov.br [Comissao Nacional de Energia Nuclear (LAPOC/CNEN-MG), Pocos de Caldas, MG (Brazil). Laboratorio de Pocos de Caldas; Navarro, Fabiano C.; Oliveira, Rodrigo J., E-mail: campus.pcaldas@unifal-mg.edu.br [Universidade Federal de Alfenas (UNIFAL), Pocos de Caldas, MG (Brazil). Instituto de Ciencia e Tecnologia

    2015-07-01

    The noble gas {sup 222}Rn is a radioactive isotope of the element radon that can be found in atmospheric air, among others gases, at broad range of concentration. This isotope decays from {sup 238}U series, which is normally found in soil and rocks, especially in fault zones and fractures, where uranium presents greater mobility. The atmospheric high concentration of this gas is frequently related to confined environments including dwellings and other buildings with low air ventilation rate. Inhalation of this gas is acknowledged by international agencies such as WHO, as the second leading cause of lung cancer, being the first among the non-smoker population. That is the reason why, some countries have defined their regions with high radon potential where it is justified the implementation of construction techniques to reduce indoor radon concentration. This paper uses the Geogenic Radon Potential (GEORP) approach aiming to identify radon prone areas in the urban zone of Pocos de Caldas - Brazil. GEORP encompasses simultaneous measurements of the soil gas permeability and radon soil gas concentration. This investigation was accomplished using RADON-JOK permeameter, a device specially developed for in situ soil gas permeability, and ALPHAGUARD, a professional radon monitor. A large variability was observed in both radon soil concentration and soil gas permeability. Some areas have presented low gas permeability due to clayey soil characteristics thus medium GEORP. The majority of the points in this paper have been identified with high radon soil gas concentration showing values that reached 1,000 kBq.m{sup -3} and presenting high radon index. (author)

  13. Relación entre estado nutricional y complicaciones posoperatorias en cardiopatías acianóticas y flujo pulmonar aumentado

    Directory of Open Access Journals (Sweden)

    Raquel Maciques Rodríguez

    Full Text Available Introducción: los primeros trabajos que asocian desnutrición y cardiopatías se reportaron en los años 50. Los lactantes cardiópatas presentan alteraciones en el crecimiento y desarrollo, y es más severo el compromiso en aquellos que se presentan con insuficiencia cardiaca y cianosis. Se describen patrones de desnutrición de acuerdo con el tipo de cardiopatía, la que puede ser aguda o crónica. Objetivos: evaluar el impacto de la intervención nutricional, como medida que contribuye a disminuir las complicaciones posoperatorias, en lactantes con cardiopatías congénitas acianóticas y desnutridos, así como relacionar la presencia de infecciones posoperatorias con hipoalbuminemia. Métodos: estudio prospectivo que incluyó a 28 lactantes con cardiopatías congénitas acianóticas, flujo pulmonar aumentado y desnutridos, en el Cardiocentro Pediátrico "William Soler", desde septiembre de 2008 hasta agosto de 2010. Fueron divididos en 2 grupos: Grupo I, no recibieron intervención nutricional; y Grupo II, recibieron intervención nutricional. El estado nutricional se determinó por el índice peso para la talla en ambos sexos. Se analizó la asociación de complicaciones posoperatorias y estado nutricional, así como la relación entre infección e hipoalbuminemia. Se aplicaron técnicas estadísticas descriptivas, se utilizaron los porcentajes y construyeron distribuciones de frecuencias absolutas y relativas. Resultados: el 69,2 % de los niños del Grupo I se encontraron desnutridos en el momento de la cirugía, y las complicaciones infecciosas estuvieron presente en el 73,3 % de los casos. En el Grupo II las complicaciones infecciosas se presentaron en el 13,3 % de los pacientes. Conclusiones: el grupo de niños desnutridos presentó mayor número de complicaciones infecciosas, las que estuvieron relacionadas a hipoalbuminemia. La intervención nutricional preoperatoria favorece una menor incidencia de complicaciones posoperatorias.

  14. Complicaciones de la apendicectomía en mayores de 65 años y su asociación con enfermedades sistémicas en el servicio de emergencia. Hospital Luis Vernaza, enero 2010 - diciembre 2012.

    OpenAIRE

    Guarquila Macías, César

    2015-01-01

    Determinar si la presencia de una patología sistémica aumenta el riesgo de sufrir una complicación en pacientes geriátricos con diagnóstico de apendicitis aguda; enumerar las complicaciones postquirúrgicas más frecuentes de la apendicectomíaen pacientes geriátricos; relacionar las complicaciones postquirúrgicas de la apendicectomía en pacientes geriátricos con el tiempo de evolución de la enfermedad y demostrar las complicaciones post-quirúrgicas de la apendicetomí...

  15. Antibióticos para prevenir las complicaciones posteriores a la extracción de dientes

    Directory of Open Access Journals (Sweden)

    2014-05-01

    Hay pruebas de que los antibióticos profilácticos reducen el riesgo de infección, alveolitis y dolor posterior a la extracción del tercer molar y dan lugar a un aumento de los efectos adversos leves y transitorios. No está claro si las pruebas de esta revisión son generalizables a los pacientes con enfermedades concomitantes o inmunodeficiencia, o a los pacientes sometidos a la extracción de dientes debido a la caries grave o a la periodontitis. Sin embargo, los pacientes en mayor riesgo de infección presentan mayor probabilidad de beneficiarse con los antibióticos profilácticos debido a que es probable que las infecciones en este grupo sean más frecuentes, se asocien con complicaciones y sean más difíciles de tratar. Debido al aumento de la prevalencia de bacterias resistentes al tratamiento con los antibióticos disponibles actualmente, los médicos deben considerar cuidadosamente la probabilidad de que el tratamiento de 12 pacientes sanos con antibióticos para prevenir una infección cause más daños que beneficios.

  16. 139. Complicaciones Neurológicas Mayores en Octogenarios Tras Cirugía Cardíaca: ¿Es la Edad un Factor Limitante?

    Directory of Open Access Journals (Sweden)

    G. Laguna

    2012-04-01

    Conclusiones: la incidencia de complicación neurológica mayor no es significativamente superior en nuestra población de octogenarios. Mientras en menores de 80 años la existencia de enfermedad vascular es el principal factor determinante, la inadecuada oxigenación cerebral, derivada de situaciones de anemia preoperatoria, parece influir más en la presencia de complicaciones neurológicas en los mayores de 80 años.

  17. Análisis de las complicaciones neurológicas en los pacientes diagnosticados de endocarditis infecciosa: 1985-2002

    Directory of Open Access Journals (Sweden)

    Tomasa Centella Hernández

    2007-07-01

    Conclusiones: Las complicaciones neurológicas son una causa frecuente de morbimortalidad en el paciente con EI. Hemos observado un incremento de los casos en las endocarditis sobre válvula na- tiva en los últimos años, sobre todo asociado al incremento de casos producidos por S. aureus. Frecuentemente la complicación neurológica es el evento que conduce al diagnóstico de EI.

  18. Caracterización clínico-epidemiológica de las complicaciones crónicas en pacientes diabéticos, tipo 2

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Agüero Batista

    2015-11-01

    Full Text Available Se realizó un estudio descriptivo, prospectivo, con el objetivo de caracterizar las principales complicaciones crónicas que se presentan en pacientes diabéticos tipo 2, del policlínico “Dr. Gustavo Aldereguía Lima” del municipio Las Tunas, así como determinar el nivel de conocimientos de los mismos en aspectos relacionados con su enfermedad, en el período comprendido de enero a diciembre del 2011. Los resultados obtenidos a través de los cuestionarios elaborados fueron analizados por el método porcentual comparativo. En los 484 pacientes estudiados existió un predominio del sexo femenino y el grupo etáreo de mayor incidencia fue el de 60 a 79 años. Las complicaciones crónicas estuvieron presentes en un considerable número de pacientes, las lesiones macroangiopáticas fueron las más relevantes, dentro de ellas, la vasculopatía periférica. La neuropatía diabética fue la más frecuente de las complicaciones microangiopáticas; así como los pacientes con un inadecuado nivel de conocimientos de su enfermedad.

  19. Gliosarcoma: un tumor cerebral poco común (Gliosarcoma, a rare brain tumor

    Directory of Open Access Journals (Sweden)

    Edison Vega

    2014-08-01

    Full Text Available Resumen (español El Gliosarcoma (GS es una neoplasia primaria agresiva y poco frecuente del Sistema Nervioso Central (SNC, compuesta de elementos astrocíticos anaplásicos y mesenquimales claramente malignos. El cuadro clínico se caracteriza por cefalea y convulsiones, que se presentan como parte de los síntomas iniciales en el 30% de los pacientes y cuyo porcentaje aumenta conforme avanza la enfermedad. Dentro de las manifestaciones secundarias, se describen cambios como alteración de la concentración y la personalidad; de manera particular las lesiones que afectan al lóbulo parietal se asocian a déficit motor o sensitivo. En cuanto al diagnóstico imagenológico por RMN, los gliomas malignos se observan bien circunscritos con edema focal y captan el contraste en la periferia con un centro hipointenso. Se reporta el caso de paciente Masculino de 45 años de edad, cuyos hallazgos clínico-imagenológicos concuerdan con los previamente descritos por lo que se plantea el diagnóstico de glioma parietooccipital derecho. Al realizar exeresis del tumor, se practicó estudio histopatológico, el cual fue reportado como un glioblastoma multiforme, y posterior al análisis inmunohistoquímico, se concluyó definitivamente como un gliosarcoma. La baja frecuencia de esta entidad patológica y la repercusión en la morbimortalidad de los pacientes que la padecen motivaron a la presentación de este caso. Abstract (english The Gliosarcoma (GS is an aggressive primary neoplasm and rare in central nervous system (CNS, composed of anaplastic astrocytic and mesenchymal elements clearly malignant. The clinical picture is characterized by headaches and seizures, presented as part of the initial symptoms in 30% of patients whose percentage increases as the disease progresses. Among the secondary manifestations, described changes as impaired concentration and personality of lesions particularly affecting the parietal lobe is associated with motor or sensory

  20. A geostatistical investigation of the spatial variation of external gamma exposure in urban area of Pocos de Caldas Plateau

    International Nuclear Information System (INIS)

    Silva, Nivaldo C.; Macacini, Jose F.; Taddei, Maria H.T.; Montano, Marcelo; Fontes, Aurelio T.

    2008-01-01

    Full text: The Pocos de Caldas Plateau has been recognized as High Level of Natural Radiation Area for a long time. It consists in an alkaline intrusion with some uranium and thorium anomalies, where the first Brazilian uranium mining and milling facilities is located. Due to these facts, the population of Pocos de Caldas city shows a great deal of concern about radiation health effects. This perception of the risks of radiation exposure leads to much confusion among the population that attributes an imaginary excess (without an scientific support) of cancer cases and deformities in newborns in the city to radiation. In order to obtain information for help radiation risks management by government and to explore the spatial variation external gamma exposure a survey in the urban area of Pocos de Caldas city was done. The measurements were performed using a Mobile Radioactivity Measurement System - Mobisys (ESM Eberline model FHT 1376). The system consists of a high-sensitivity 5-liter scintillation detector, an electronic for measurement system that is able to on-line separate natural and artificial gamma radiation (Natural Background Rejection Detector NBR), one compact Global Positioning System GPS and a computer (notebook). Data was collected at approximately 50,000 points spread over all streets of city. The obtained results ranged from 40 nSv.h -1 to 420 nSv.h -1 where the mean value was 112 nSv.h -1 . The spatial distribution of gamma exposure over the city is quite homogeneous with lowest and highest values in western and southern area, respectively. (author)

  1. Estimative of alpha radiation dose due to natural concentration of Ra-226 in waters from Pocos de Caldas

    International Nuclear Information System (INIS)

    Sigaud, G.M.

    1979-01-01

    A dosimetric model for calculating the annual dose equivalent for an individual and the annual collective dose equivalent from 226 Ra is developed. This model is applied to the measured concentrations of 226 Ra in waters of the hydro graphic basins of the Pocos de Caldas plateau, using the pathways of drinking water and ingestion of food grown in irrigated fields. A linear model for simulating potential 226 Ra contamination of the waters of the region is also applied, and the doses from these contaminations are estimated using the dosimetric model developed. (author)

  2. The average concentrations of 226Ra and 210Pb in foodstuff cultivated in the Pocos de Caldas plateau

    International Nuclear Information System (INIS)

    Hollanda Vasconcellos, L.M. de.

    1984-01-01

    The average concentrations of 226 Ra and 210 Pb in vegetables cultivated in the Pocos de Caldas plateau, mainly potatoes, carrots, beans and corn and the estimation of the average transfer factors soil-foodstuff for both radionuclides, were performed. The total 226 Ra and 210 Pb content in the soil was determined by gamma spectrometry. The exchangeable fraction was obtained by the classical radon emanation procedure and the 210 Pb was isolated by a radiochemical procedure and determined by radiometry of its daughter 210 Bi beta emissions with a Geiger Muller Counter. (M.A.C.) [pt

  3. 19 CFR 134.14 - Articles usually combined.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Articles usually combined. 134.14 Section 134.14... TREASURY COUNTRY OF ORIGIN MARKING Articles Subject to Marking § 134.14 Articles usually combined. (a) Articles combined before delivery to purchaser. When an imported article is of a kind which is usually...

  4. Reintervenciones por complicaciones después de realizada colecistectomía laparoscópica Reinterventions in complications of the laparoscopic cholecystectomy

    Directory of Open Access Journals (Sweden)

    Rosalba Roque González

    2011-09-01

    Full Text Available Durante estos años varios centros con experiencia en colecistectomía laparoscópica han publicado sus complicaciones y tratamiento a estas. El objetivo de este estudio es describir la experiencia en 23 pacientes reintervenidos por complicaciones posoperatorias de la colecistectomía laparoscópica realizadas en el Centro Nacional de Cirugía de Mínimo Acceso, según el reporte de los resultados obtenidos. Se realizó un estudio descriptivo, retrospectivo y longitudinal, en el que se revisaron las historias clínicas de los pacientes reintervenidos por sospecha de complicaciones después de la colecistectomía laparoscópica, en el período comprendido de enero de 1998 a junio de 2010. Durante el período de la investigación se realizaron 10 039 colecistectomías laparoscópicas. Fueron reintervenidos 23 pacientes (0,2 %, con una edad media de 49 años (rango 22 a 73 años, DE ± 10. La relaparoscopia fue la vía para la reintervención (70 % y solo 3 (13 % requirieron cirugía abierta. Fue la colangiopancreatografía retrógrada endoscópica un procedimiento útil para complementar la solución de algunas de estas complicaciones. El tiempo quirúrgico medio en las reintervenciones fue de 67 min (rango 30-120 min, la estadía hospitalaria tuvo una media de 4 y 5 días respectivamente. Hubo 2 pacientes (9 % que se reintervinieron tardíamente, a las 72 h de la colecistectomía, que fallecieron con cuadros de shock séptico. La laparoscopia es un procedimiento adecuado para las reintervenciones en pacientes con sospecha de complicaciones después de colecistectomía laparoscópica, con menor morbilidad y mortalidad sobre otros procederes, y su eficacia para el tratamiento de estas complicaciones está demostrada.Over past years some centers with experience in laparoscopic cholecystectomy have published the complications and treatment of this procedure. The aim of present paper is to describe the experience in 23 patients re-operated on due to

  5. Factores pronósticos de complicaciones postoperatorias en el trasplante hepático Prognostic factors associated with postoperative complications in liver transplantation

    Directory of Open Access Journals (Sweden)

    A. Rodríguez-Ariza

    2008-03-01

    Full Text Available Objetivo: la evolución postoperatoria de los pacientes sometidos a trasplante hepático ortotópico (THO se encuentra frecuentemente asociada a la aparición de diversas complicaciones tales como disfunción renal, rechazo agudo, infecciones y complicaciones neurológicas. Estas complicaciones constituyen las causas más significativas de morbilidad y mortalidad tempranas en pacientes que reciben un THO. El propósito del presente estudio es la identificación de factores relacionados con las distintas complicaciones postoperatorias del THO. Diseño experimental: se llevó a cabo un estudio prospectivo. Pacientes: se analizaron 78 variables en 32 pacientes consecutivos sometidos a THO. Utilizando un análisis de regresión logística se identificaron aquellos factores asociados de forma independiente con la aparición de complicaciones postoperatorias. Resultados: el análisis multivariante demostró que los niveles pretrasplante en suero de malondialdehído y creatinina estaban asociados con el desarrollo de disfunción renal. Los niveles pretrasplante de hemoglobina y las unidades de plaquetas administradas durante la cirugía fueron factores pronósticos de infecciones. El rechazo agudo fue pronosticado por los niveles séricos de γ-glutamil transpeptidasa y de bilirrubina total. Los niveles pretrasplante de sodio y glutaredoxina en suero estuvieron asociados con complicaciones neurológicas. Conclusiones: proponemos estos marcadores para la identificación de pacientes de alto riesgo, permitiendo una vigilancia y/o tratamiento anticipados que mejorarán la morbilidad y la supervivencia en pacientes sometidos a THO.Objectives: the postoperative evolution of patients submitted to orthotopic liver transplant (OLT is frequently associated with the appearance of different types of complications such as renal failure, graft rejection, infections, and neurological disorders. These complications are the most significant causes of early morbidity

  6. The hydrothermal alteration in the context of geologic evolution from Pocos de Caldas Alkaline Massif, MG-SP

    International Nuclear Information System (INIS)

    Garda, G.M.

    1990-01-01

    The Pocos de Caldas Alkaline Massif covers 800 km 2 , a quarter of which is hydrothermally altered. Such proportion is uncommon, when compared to the know alkaline massifs of the world. The hydrothermal alteration is associated with Zr, U and Mo mineralizations which are predominantly located in the central-southern portion of the massif, in the central-eastern circular structure. The colour of the altered rock (and its soil) in that area is typically whitish beige to yellowish white and is regionally called potassic rock. The Osamu Utsumi Mine, also referred to as the uranium ore of Campo do Cercado, is located 25 Km to the south of Pocos de Caldas City and was explored, from 1977 to 1989, through the open pit method. A sequence of alteration minerals adapted to lowering temperatures should be expected; however, only illite and alkaline feldspar are observed in the hydrothermally altered portions of the massif, and their formation must have been controlled mainly by kinetic, other than thermal factors. The irrestrict circulation of relatively hotter hydrothermal fluids must have happened at the beginning of the process, diminishing immediately after the cooling of the brecciated areas (and the subjacent magmatic body), leading the system to kinetics levels that made subsequent hydrothermal alteration impossible. (author)

  7. Geoprocessing as a technical tool for radiological assessment in the urban area of Pocos de Caldas, MG

    International Nuclear Information System (INIS)

    Silva, Nivaldo C.; Macacini, Jose F.; Alberti, Heber L.C.

    2009-01-01

    The present study will introduce a methodology for spatial evaluation of external gamma dose throughout an urbanized region. As a case study, geoprocessing techniques were used to gather data, perform statistical and spatial data treatment related to natural gamma radioactivity throughout the Pocos de Caldas urban area. This information, which was initially punctual, could be correlated with the number of people exposed to natural radiation using the database from the census made available by IBGE (Brazilian Geography and Statistics Institute). The census sector is the smallest piece of territory, with identifiable physical boundaries in the field, with adequate size for research operations. All 54,237 geoprocessed external dose values, within dosimetry ranges, presented a variation from 0.33 mSv year -1 to 3.51 mSv year -1 , with an average equal to 0.95 mSv year -1 . The results obtained, when compared to worldwide dose values (0.06 mSv year -1 to 1.23 mSv year -1 with an average of 0.48 mSv year -1 ) indicated that though the average value in Pocos de Caldas - 0.95 mSv year -1 - is almost twice the world average, it is within the dosimetry range found in other countries. Nevertheless, the region has some areas with values higher than those observed elsewhere in the world, though in areas with lower population density. (author)

  8. Microorganismos patógenos y potencialmente patógenos en secreciones genitales de gestantes a término asociados a complicaciones posnatales

    Directory of Open Access Journals (Sweden)

    Tania Castellanos Medina

    2013-09-01

    Full Text Available Introducción: tanto las infecciones puerperales como las neonatales precoces reflejan probablemente los microorganismos que están presentes en la vagina en el período cercano al parto. Objetivo: establecer la relación entre los microorganismos identificados en las secreciones genitales de las gestantes a término y el desarrollo de sepsis neonatal y puerperal, así como vincular dichas complicaciones con los agentes diagnosticados. Métodos: se realizó un estudio longitudinal y prospectivo en los servicios de microbiología, obstetricia, perinatología y neonatología del Hospital General Docente "Dr. "Juan Bruno Zayas Alfonso", de Santiago de Cuba, desde julio de 2009 hasta marzo de 2010. Se identificaron microorganismos en 179 muestras cervicovaginales, las cuales fueron procesadas en el laboratorio de microbiología según las normas vigentes. Resultados: los microorganismos más identificados resultaron los géneros Mycoplasmas y Chlamydias (78,2 y 69,3%, respectivamente y fueron los que con mayor frecuencia se asociaron. Un porcentaje elevado de las gestantes (67,0 %, tenía más de un agente en sus secreciones genitales. Después del parto hubo un hallazgo mayor de infecciones en el producto de la concepción (21,8 % que en las puérperas (3,9% y la mayoría de estas complicaciones se relacionaron con la presencia de 2 o más microorganismos. Conclusiones: las asociaciones de microorganismos patógenos o potencialmente patógenos en las secreciones genitales de embarazadas a término, aumentan el riesgo de complicaciones posnatales.

  9. Complicaciones maternas de la cesárea en gestantes a término en periodo expulsivo en un hospital general de Lima, Perú

    Directory of Open Access Journals (Sweden)

    Javier Puma

    2015-01-01

    Full Text Available Objetivo: Describir las complicaciones maternas de la cesárea en gestantes a término en periodo expulsivo en un hospital general. Material y métodos: Estudio descriptivo, observacional, retrospectivo, tipo serie de casos, realizado en el Hospital Nacional Cayetano Heredia entre el 1 de enero de 2011 hasta el 31 diciembre de 2012. Se incluyeron 67 gestantes a término operadas en periodo expulsivo. Se revisaron las historias clínicas de las pacientes, se registraron las características clínicas y las complicaciones maternas. Resultados: En el periodo de estudio se realizaron 4 218 cesáreas, siendo el 1,84% hechas en periodo expulsivo. En general, 59/ 67 (88,1% presentaron algún tipo de complicación. Se observaron 8 casos de hipotonía uterina (11,9% y 2 (2,9% de atonía. En 5 (7,4% pacientes ocurrieron desgarros de segmento adyacente a la histerotomía, siendo 2 de ellos asociados a compromiso de cuerpo uterino y vagina, y 4 (5,9% casos a laceración de arteria uterina, uno fue bilateral. No se produjeron lesiones en tracto urinario ni digestivo y tampoco hubo necesidad de reintervención quirúrgica. Cuatro pacientes presentaron hemorragia puerperal, dos asociados a hipotonía uterina post cesárea. En 56 (83,5% casos ocurrió anemia post operatoria. Hubo 1 (1,5% caso de endometritis, 3 (4,5% infecciones de herida operatoria. Conclusiones: La cesárea realizada en período expulsivo ocasiona complicaciones frecuentes, algunas muy severas.

  10. El papel de enfermería en atención primaria para prevenir y detectar las complicaciones de los diabéticos tipo 2

    OpenAIRE

    Gomez Marciel, Aitor

    2017-01-01

    El aumento de la población, de la expectativa de vida y de los malos hábitos como el sedentarismo, la dieta inadecuada y la obesidad influyen directamente en la incidencia y prevalencia de diabetes mellitus en el mundo, caracterizándola como epidemia mundial. Según la Organización Mundial de la Salud, 422 millones de adultos tenían diabetes en 2014. El objetivo de este trabajo ha sido conocer el rol de enfermería para evitar y detectar complicaciones y comprobar si los cuidados que efectúa so...

  11. Embarazo adolescente como factor de riesgo para complicaciones obstétricas y perinatales en un hospital de Lima, Perú

    Directory of Open Access Journals (Sweden)

    Javier A. Okumura

    2014-12-01

    Full Text Available Objetivos: analizar el riesgo de complicaciones obstétricas y perinatales en adolescentes embarazadas en un hospital de Lima, Perú. Métodos: estudio de cohorte retrospectiva de 67.693 gestantes atendidas en el período 2000-2010. Se evaluó complicaciones obstétricas y perinatales. Las adolescentes se clasificaron en tardías (15-19 años y tempranas (< 15 años y se compararon con las adultas (20-35 años. Se calculó OR ajustados por educación, estado civil, control prenatal, gestaciones previas, paridad e IMC pregestacional. Resultados: se encontró mayor riesgo de cesárea (OR=1,28; IC95%=1,07-1,53 e infección puerperal (OR=1,72; IC95%=1,17-2,53 en las adolescentes menores de 15 años, así como mayor riesgo (OR=1,34; IC95%=1,29-1,40de episiotomía en las adolescentes tardías. Asimismo, se identificó un menor riesgo del embarazo adolescente para preeclampsia (OR=0,90; IC95%=0,85-0,97, hemorragia de la 2da mitad del embarazo (OR=0,80; IC95%=0,71-0,92, ruptura prematura de membranas (OR=0,83; IC95%=0,79-0,87, amenaza de parto pretérmino (OR=0,87; IC95%=0,80-0,94 y desgarro vaginal (OR= 0,86; IC95%=0,79-0,93. Conclusión: el embarazo se comporta como factor de riesgo para ciertas complicaciones obstétricas en la población adolescente, especialmente en las adolescentes tempranas. Existen además otros factores, que sumados a la edad materna, constituyen la necesidad de formar equipos multidis-ciplinarios para reducir complicaciones obstétricas en esta población.

  12. Complicaciones orales en pacientes sometidos a radioterapia: revisión de literatura / Oral Complications in Patients Undergoing Radiotherapy: A Review of Literature

    OpenAIRE

    Hurtado Redondo, Diana Carolina; Universidad Nacional de Colombia sede Bogotá; Estrada Montoya, John Harold; Universidad Nacional de Colombia sede Bogotá

    2013-01-01

    Objetivo: Presentar los principales conceptos de radiobiología, radioterapia en cavidadoral y complicaciones asociadas, para llevar a cabo acciones seguras de tipo preventivo yterapéutico por parte del profesional o del equipo tratante. Método: La revisión se llevó acabo en diferentes bases de datos y revistas acerca del manejo odontológico de pacientessometidos a radioterapia. Resultados: Actualmente, el tratamiento para el cáncer tiene unenfoque multidisciplinario, en el cual participan dis...

  13. Complicaciones presentadas en pacientes mayores de 65 años ingresados por fractura de cadera en un hospital andaluz de tercer nivel

    OpenAIRE

    López-Hurtado, Felipe; Miñarro del Moral, Rosa María; Arroyo Ruiz, Verónica; Rodríguez Borrego, Mª Aurora

    2015-01-01

    Objetivo: Conocer las complicaciones que se han producido en pacientes mayores de 65 años, ingresados en un hospital andaluz de tercer nivel durante el año 2012, con diagnóstico principal de fractura de cadera. Metodología: Diseño: Se realizó un estudio descriptivo transversal. Ámbito, periodo y sujetos de estudio: Pacientes ingresados en el año 2012 mayores de 65 años con diagnóstico principal de fractura de cadera. Variables principales: Morbimortalidad recogida en el C...

  14. Complicaciones de la Ventilación Mecánica. Unidad de Cuidados Intensivos Pediátricos Holguín

    OpenAIRE

    Carlos Alberto Córdova-Vega; Hèctor Pupo-Rodríguez; Andrés Andrés-Matos

    2013-01-01

    Se realizó un estudio prospectivo, descriptivo en pacientes ingresados en la Unidad de Cuidados Intensivos del Hospital Pediátrico de Holguín y que necesitaron ventilación mecánica por un tiempo mayor a las 24 horas, durante el año 2010, con el objetivo de conocer las complicaciones relacionadas con este proceder. Dentro de los resultados encontramos que las afecciones neurológicas (35,29%), las respiratorias y las malformaciones congénitas (17,64%) fueron las principales causas que llevaron ...

  15. Evaluation of NORM concentration in water treatment of Pocos de Caldas municipality, MG, Brazil: preliminary results; Avaliacao da presenca de NORM no tratamento de agua do municipio de Pocos de Caldas: resultados preliminares

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Adriano Mota; Villegas, Raul A.S.; Fukuma, Henrique Takuji, E-mail: htfukuma@cnen.gov.br, E-mail: adrianomotaferreira@gmail.com [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)

    2014-07-01

    NORM is the acronym used to refer to naturally occurring radioactive materials. Besides being objects of study and monitoring such materials can be used as raw material or as by-products or waste of industrial activities. Oil and gas, mining and water treatment are examples of facilities that can handle NORM. In such cases, their concentration at significant levels from the perspective of environmental and occupational radiation protection may occur. This study aims to evaluate the presence of the natural radioactive {sup 238}U and {sup 232}Th series in the treatment of city water elements Pocos de Caldas - MG (water, materials and waste). The study can serve as an indication of the necessity of a more detailed review in the locally and in the country on this radiological issue. (author)

  16. Detección de las complicaciones en los pacientes diabéticos que asisten a la unidad básica la libertad, durante los meses de abril y mayo del año 2006

    Directory of Open Access Journals (Sweden)

    Elisa Katie Vergel-Arevalo

    2006-12-01

    Full Text Available La diabetes continua siendo uno de los mayores problemas de salud pública en el mundo, coma consecuencia de complicaciones tales como neuropatías, oftalmopatias, nefropatías, Hipertensión Arterial (HTA, alteraciones micro y macrovasculares. La presente revisión pretende exponer las complicaciones encontradas en una muestra de 14 pacientes diabéticos de la Unidad Básica la Libertad de la ciudad de Cúcuta (Colombia, con el objetivo de detectar tempranamente las complicaciones propias de la Diabetes. El principal respaldo de esta investigación se basa en los grandes estudios epidemiológicos que han demostrado que el control adecuado de la glicemia previene o retarda las complicaciones. Al valorar los pacientes diabéticos se tomaron variables sociodemográficas como sexo, edad, estrato, ocupación y nivel educativo; alteraciones en los niveles de glicemia casual en sangre, en el estado neurológico, oftalmológico, factores que puedan propiciar pie diabético, antecedentes de complicaciones agudas, valores de presión arterial y prácticas como dieta balanceada y ejercicios

  17. Guia de atencion integral para la prevencion, deteccion temprana y tratamiento de las complicaciones del embarazo: Sección de Toxoplasmosis

    Directory of Open Access Journals (Sweden)

    Jorge Alberto Cortes

    Full Text Available Resumen Como parte de la Guia de atencion integral para la prevencion, deteccion temprana y tratamiento de las complicaciones del embarazo, desarrollada y financiada por el Departamento de Ciencia, Tecnologia e Innovacion, Colciencias, y el Ministerio de Salud y Proteccion Social de Colombia, se seleccionó a la infeccion por Toxoplasma para el desarrollo de recomendaciones para su prevencion, diagnostico y tratamiento. La infeccion por Toxoplasma gondii (T. gondii durante el embarazo puede resultar en graves complicaciones para el feto y dejar importantes secuelas al recien nacido. Se realizo una guia basada en la mejor evidencia disponible en la literatura cientifica, con especial pertinencia a la informacion colombiana. Un consenso de expertos en parasitologia, ginecologia, neonatologia e infectologia, tanto de adultos como pediatrica, desarrollo las recomendaciones. Se propone que las recomendaciones de esta guia de atencion integral sean utilizadas por los profesionales de salud de los programas de atencion del embarazo del pais con el fin de disminuir la morbilidad y mortalidad atribuible a esta enfermedad. Se formulan recomendaciones especificas para el diagnostico desde el primer trimestre, consejos de prevencion en las mujeres no infectadas, identificacion de la infeccion del feto o del recien nacido y recomendaciones de tratamiento en estos escenarios.

  18. Immunological response in cases of complicated and uncomplicated bartonellosis during pregnancy Respuesta inmunologica en casos de bartonelosis con y sin complicaciones durante el embarazo

    Directory of Open Access Journals (Sweden)

    Erick Huarcaya

    2007-10-01

    Full Text Available Bartonellosis (Carrion's Disease during pregnancy is associated with high rates of maternal and perinatal mortality. We report the immunological patterns in two cases of human bartonellosis during pregnancy. One patient had an uncomplicated course while the second patient developed life threatening anasarca and cardiac tamponade. The patient with a complicated course had a Th1 response with a higher elevation of IL-10. This elevation has been associated with poor outcome pregnancies during bacterial infections.Bartonelosis (Enfermedad de Carrión durante el embarazo esta asociado a una alta tasa de mortalidad maternal y perinatal. Reportamos el perfil inmunológico de dos casos de Bartonelosis humana en el embarazo. Una paciente tuvo un curso sin complicaciones, mientras la segunda presento complicaciones severas de anasarca y tamponamiento cardiaco. La paciente con curso complicado tuvo un patrón de repuesta Th1, con una elevación de IL-10, que se ha asociado a mal pronóstico en infecciones durante embarazo.

  19. Contribution to the study of uranium migration and some trace elements in solution from Pocos de Caldas uranium mining

    International Nuclear Information System (INIS)

    Zenaro, R.

    1989-01-01

    It was studied the chemical composition of ground water from four boreholes as a contribution to the hydrogeochemical studies in the Pocos de Caldas uranium mining. Methods for water analyses were selected and optimized in order to determine the main anions, specially the ones which form stable complexes with uranium ions. Fluoride and chloride were determined by potentiometry; phosphate, nitrate and silicate by spectrophotometry. Cations were determined by atomic absorption spectrophotometry flame emission and argon plasma emission excited by continuous current arch (DCP). Uranium was determined by fluorimetry with a concentration range from 3 to 7 ppb and its distribution calculated among the different species into solution through the measures of pH, Eh, anion amounts and stability of their respective complexes. (author) [pt

  20. Study of the feasibility of the utilization of clays from Poco Fundo (MG) for its use in bricks fabrication

    International Nuclear Information System (INIS)

    Gaspar Junior, L.A.; Souza, M.H.O.; Moreno, M.M.T.

    2012-01-01

    This work aimed to make an analysis of mineralogical (Macroscopic Description and X-Ray Diffraction), chemical (X-Ray Fluorescence and Organic Carbon Analysis) and ceramic (Particle Size Distribution, Mechanical Resistance, Water Absorption, Apparent Porosity, among others) properties of the alluvial clays collected in Poco Fundo county - Minas Gerais State, Brazil - in order to confirm the feasibility of these clays for bricks manufacturing. There were collected 4 samples from the main potteries of the county, and they were nominated PF-01, PF-02, PF-03 and MAC-01. The clays from these region display high content of quartz, kaolinite and present refractory behavior, and the alkalis content (Na 2 O and K 2 O) is low, because the studied area suffered an intense weathering process. The sample PF-03 presented the most promising ceramic results, mainly due to the lower content in silica and higher amounts of organic matter, denoting a clay coming from a swampy area. (author)

  1. Thorium deposit of Morro do Ferro in Pocos de Caldas, Brazil: an analogue of a radioactive waste repository

    International Nuclear Information System (INIS)

    Franca, E.P.; Carlos, M.T.; Sachett, I.A.; Campos, M.J.M.T. de; Lei, W.; Eisenbud, M.; New York Univ., NY

    1986-01-01

    A highly weathered deposit of thorium and rare earth elements located near the summit of a hill (Morro do Ferro) in Pocos de Caldas M.G., is being studied as an analogue for a radioactive waste repository that, sometime in the distant future, may be eroded to the surface or intruded by groundwater. Th - serves as an analogue for Pu 4+ and La 3+ as an analogue for Cm 3+ and Am 3+ . The mobilization rates of the analogue elements by groundwater are so slow (10 -7 to 10 -9 per year), as to suggest that essentially complete radioactive decay of transuranic actinides would occur in place, even under the unfavorable conditions that exist at a site such as this. (Author) [pt

  2. Study of the application of non-plastic clays from Pocos de Caldas - part 1: chemical-mineralogic characterization

    International Nuclear Information System (INIS)

    Roveri, C.D.; Mariano, N.A.; Faustino, L.M.; Aielo, G.F.; Pinto, L.P.A.; Maestrelli, S.C.

    2011-01-01

    Pocos de Caldas is an important 'hidrotermomineral' center of Brazil, where can be found non-plastic clays deposits with no significant records about its characterization; this fact difficult the studies of industrial application. These nonplastic clays, not used, have been stored in sheds or open, which creates a high cost to the industry, and become an environmental liability. In the present work, the chemical-mineralogical study of six samples of non-plastic clays was realized, to expand the horizons of researches about such materials. This preliminary study showed that, overall, the samples are composed of refractory minerals such as kaolinite and gibbsite, with less significant amounts of other phases such as quartz, illite and vermiculite. The chemical analysis permitted the grouping of raw materials into two groups according to their refractories proprieties, guiding to the subsequent characterization. (author)

  3. Revisiting Pocos de Caldas. Application of the co-precipitation approach to establish realistic solubility limits for performance assessment

    International Nuclear Information System (INIS)

    Bruno, J.; Duro, L.; Jordana, S.; Cera, E.

    1996-02-01

    Solubility limits constitute a critical parameter for the determination of the mobility of radionuclides in the near field and the geosphere, and consequently for the performance assessment of nuclear waste repositories. Mounting evidence from natural system studies indicate that trace elements, and consequently radionuclides, are associated to the dynamic cycling of major geochemical components. We have recently developed a thermodynamic approach to take into consideration the co-precipitation and co-dissolution processes that mainly control this linkage. The approach has been tested in various natural system studies with encouraging results. The Pocos de Caldas natural analogue was one of the sites where a full testing of our predictive geochemical modelling capabilities were done during the analogue project. We have revisited the Pocos de Caldas data and expanded the trace element solubility calculations by considering the documented trace metal/major ion interactions. This has been done by using the co-precipitation/co-dissolution approach. The outcome is as follows: A satisfactory modelling of the behaviour of U, Zn and REEs is achieved by assuming co-precipitation with ferrihydrite. Strontium concentrations are apparently controlled by its co-dissolution from Sr-rich fluorites. From the performance assessment point of view, the present work indicates that calculated solubility limits using the co-precipitation approach are in close agreement with the actual trace element concentrations. Furthermore, the calculated radionuclide concentrations are 2-4 orders of magnitude lower than conservative solubility limits calculated by assuming equilibrium with individual trace element phases. 34 refs, 18 figs, 13 tabs

  4. Revisiting Pocos de Caldas. Application of the co-precipitation approach to establish realistic solubility limits for performance assessment

    Energy Technology Data Exchange (ETDEWEB)

    Bruno, J.; Duro, L.; Jordana, S.; Cera, E. [QuantiSci, Barcelona (Spain)

    1996-02-01

    Solubility limits constitute a critical parameter for the determination of the mobility of radionuclides in the near field and the geosphere, and consequently for the performance assessment of nuclear waste repositories. Mounting evidence from natural system studies indicate that trace elements, and consequently radionuclides, are associated to the dynamic cycling of major geochemical components. We have recently developed a thermodynamic approach to take into consideration the co-precipitation and co-dissolution processes that mainly control this linkage. The approach has been tested in various natural system studies with encouraging results. The Pocos de Caldas natural analogue was one of the sites where a full testing of our predictive geochemical modelling capabilities were done during the analogue project. We have revisited the Pocos de Caldas data and expanded the trace element solubility calculations by considering the documented trace metal/major ion interactions. This has been done by using the co-precipitation/co-dissolution approach. The outcome is as follows: A satisfactory modelling of the behaviour of U, Zn and REEs is achieved by assuming co-precipitation with ferrihydrite. Strontium concentrations are apparently controlled by its co-dissolution from Sr-rich fluorites. From the performance assessment point of view, the present work indicates that calculated solubility limits using the co-precipitation approach are in close agreement with the actual trace element concentrations. Furthermore, the calculated radionuclide concentrations are 2-4 orders of magnitude lower than conservative solubility limits calculated by assuming equilibrium with individual trace element phases. 34 refs, 18 figs, 13 tabs.

  5. Statistical modelling of usual intake. Scientific report submitted to EFSA

    NARCIS (Netherlands)

    Voet, van der H.; Klaveren, van J.D.; Arcella, D.; Bakker, M.; Boeing, H.; Boon, P.E.; Crépét, A.; Dekkers, A.; Boer, de W.; Dodd, K.W.; Ferrari, P.; Goedhart, P.W.; Hart, A.; Heijden, van der G.W.A.M.; Kennedy, M.; Kipnis, V.; Knüppel, S.; Merten, C.; Ocké, M.; Slob, W.

    2010-01-01

    Within the EFSA Article 36 project “European Tool Usual Intake” (ETUI) a workshop was organised in May 2010 where the different available models to calculate usual intake were presented and discussed. This report integrates the workshop background document, the presentations given by experts, and

  6. Comparing four methods to estimate usual intake distributions

    NARCIS (Netherlands)

    Souverein, O.W.; Dekkers, A.L.; Geelen, A.; Haubrock, J.; Vries, de J.H.M.; Ocke, M.C.; Harttig, U.; Boeing, H.; Veer, van 't P.

    2011-01-01

    Background/Objectives: The aim of this paper was to compare methods to estimate usual intake distributions of nutrients and foods. As ‘true’ usual intake distributions are not known in practice, the comparison was carried out through a simulation study, as well as empirically, by application to data

  7. Análisis de costo de la enfermedad, del tratamiento, las complicaciones e intervenciones de la hipercolesterolemia en México en 2016.

    Science.gov (United States)

    Baeza-Cruz, German; Peniche-Otero, Gustavo; Alva-Esqueda, Mónica E; Naranjo-Muedano, Mariana; Soria-Suárez, Noé; Morales-Flores, Héctor J

    2018-04-20

    Describir los costos y el impacto económico de la atención de pacientes diagnosticados con hipercolesterolemia en México en el año 2016. METODOLOGíA: Se desarrolla una evaluación económica del tipo análisis de costo de la enfermedad donde se cuantifican los recursos médicos utilizados para el tratamiento de la hipercolesterolemia así como para sus complicaciones. Los costos de los recursos médicos utilizados son obtenidos de los costos unitarios por nivel de atención del Instituto Mexicano del Seguro Social (IMSS) así como de las licitaciones publicadas en el portal de compras del IMSS. El uso de recursos se obtiene mediante un panel de expertos y para el porcentaje de presencia de las complicaciones se efectúa una revisión de literatura. Los costos médicos directos son estimados multiplicando la frecuencia de uso por el costo unitario, agrupándolos y obteniendo así los costos individuales de cada recurso médico. Los casos de hipercolesterolemia en prevención secundaria con enfermedad coronaria y enfermedad cardiovascular representan un mayor costo promedio anual ($111,835.19, D.E. $84,276.37), seguido de la hipercolesterolemia en prevención secundaria con enfermedad coronaria sin enfermedad cardiovascular ($56,352.13, D.E. $29,004.04), los cuales no incluyen los costos generados por las complicaciones. El resto de los grupos de hipercolesterolemia representan una carga económica menor. La carga económica de la hipercolesterolemia representa en promedio por caso al año $258,761.37, esto traducido a los aproximadamente 445,075 de casos diagnosticados y tratados al año representaría un impacto económico en el sistema de salud de más de ciento quince mil millones ($115,168,331,355.11). Copyright © 2018. Published by Elsevier Inc.

  8. Incapacidad laboral por diabetes mellitus: características epidemiológicas y complicaciones macro y microangiopáticas más frecuentes

    Directory of Open Access Journals (Sweden)

    Raúl Jesús Regal Ramos

    2014-03-01

    Full Text Available La diabetes mellitus (DM es la enfermedad metabólica más frecuente y conlleva la disminución en la calidad de vida de los sujetos que la padecen, así como la pérdida de años de vida productiva a consecuencia de las complicaciones crónicas o de la mortalidad. Objetivo: Conocer las características epidemiológicas de los pacientes con invalidez permanente (IP debida a DM y conocer cuáles son las complicaciones más frecuentes que motivaron la IP y su relación con las distintas ocupaciones. Método: Se realizó un estudio descriptivo en el que se recogieron pacientes valorados en la Unidad Médica de la Dirección Provincial del INSS de Madrid entre los años 2005 a 2011 con el diagnóstico de diabetes. Se excluyeron aquellos expedientes que no fueron calificados como IP, aquellos que presentaban otras patologías no relacionadas con la diabetes subsidiarias de probable incapacidad (como procesos oncológicos, demencia, esclerosis múltiple,.. y los casos de diabetes secundarias. Se estudian las variables edad, sexo, estado civil, profesión, régimen de afiliación a la Seguridad Social, y las recogidas en el apartado diagnóstico del informe médico de síntesis (tipo de diabetes, complicaciones derivadas de la DM y factores de riesgo cardiovascular. Resultado: El total de pacientes estudiados fue de 896. Respecto a la población general ocupada de nuestro entorno observamos un 31% más de varones (p< 0,0005; Razón de prevalencia =1,56 y un 28% más de ocupaciones del grupo VII de la CNO-11 (industria y construcción (p < 0,005; Razón de prevalencia =2,3. El 48% de las profesiones científicas y el 36 % de las administrativas estaban diagnosticados de oftalmopatía. El 39% de trabajadores de industria y construcción estaban diagnosticados de algún grado de coronariopatía. Conclusión: Nuestros resultados permiten objetivar que la oftalmopatía es la complicación que más se asocia a invalidez permanente en profesiones de alta

  9. Adolescentes estudantes: conhecimentos das complicações do aborto provocado Adolescentes estudiantes: conocimientos de las complicaciones de abortamiento Female teenager students: knowledge abortion complications

    Directory of Open Access Journals (Sweden)

    Divanise Suruagy Correia

    2011-09-01

    Full Text Available O objetivo deste estudo foi identificar o conhecimento das complicações do aborto provocado e sua relação coma a idade. Estudo transversal, realizado em escolas de Maceió, Alagoas, com estudantes dos 12 aos 19 anos. A amostra foi calculada considerando-se os dados de internação de curetagem pós aborto. Usou-se o programa Epi Info versão 3.6 para análise dos dados. Das 2592 adolescentes estudadas, 65,64% não conheciam nenhuma complicação do aborto provocado e as complicações mais citadas foram morte e esterilidade. Manifestações clínicas do aborto foram incorretamente citadas como complicações. Encontrou-se significação entre o conhecimento das complicações esterilidade e hemorragia e idade. A morte foi significativa para menores de 15 anos e a esterilidade para as maiores. Conclui-se que as adolescentes não conhecem corretamente as complicações do aborto provocado, o que demonstra o risco daquelas que o provocam, verifica-se, portanto, a necessidade de maiores esclarecimentos sobre o tema bem como da educação sexual.El objetivo de este estudio fue identificar el conocimiento de las complicaciones del aborto inducido y su relación con la edad. Estudio transversal, realizado en escuelas, de Maceió, Alagoas, Brasil, con adolescentes de los 12 a los 19 años. La muestra fue calculada a partir de los datos de las internaciones para legrado después del aborto. Fue usado para analiza de los datos el Epi Info. De las 2592 adolescentes estudiadas, 65.64% no sabían de ninguna complicación del aborto inducido y las complicaciones mas citadas fueran muerte y esterilidad. Las manifestaciones clínicas del aborto también fueran citadas como complicaciones. Hube significación entre el conocimiento de la esterilidad y la hemorragia y edad. La muerte fue significativa para las menores de 15 años y la esterilidad para las más grandes. Se concluye que las adolescentes no sabían correctamente las complicaciones del aborto

  10. “Integración de un Paradigma: Mecanismos Biomoleculares y Patogénicos, Precursores de las Complicaciones de la Diabetes”

    Directory of Open Access Journals (Sweden)

    Mario Sánchez Medina

    2005-03-01

    Inmensa cantidad de información científica y periodística hay sobre el tema del progreso de la diabetes en el mundo, particularmente en los países desarrollados, que se refleja también en los países en desarrollo con inquietante incertidumbre, por el incremento vertiginoso de la enfermedad. Uno de los problemas que más concierne a los profesionales de la salud y, desde luego, a las familias que tienen diabetes, obesidad y factores genéticos predisponentes en sus antecedentes, es el hallazgo de la presencia de complicaciones microvasculares antes de que ellos mismos sepan que están desarrollando la enfermedad...

  11. iDESWEB: Ejercicio: JavaScript: Una página web con un poco de código (encuesta de valoración)

    OpenAIRE

    Luján Mora, Sergio

    2013-01-01

    Solución del ejercicio "JavaScript: Una página web con un poco de código (encuesta de valoración)" del curso MOOC iDESWEB, Introducción al desarrollo web. Página web del curso: http://idesweb.es/

  12. Analgesia peridural contínua: análise da eficácia, efeitos adversos e fatores de risco para ocorrência de complicações Analgesia peridural continua: análisis de la eficacia, efectos adversos y factores de riesgo para ocurrencia de complicaciones Continuous epidural analgesia: analysis of efficacy, side effects and risk factors

    Directory of Open Access Journals (Sweden)

    Leonardo Teixeira Domingues Duarte

    2004-06-01

    . Todavia, não se pode dispensar rigorosa vigilância a fim de se obter analgesia satisfatória e diminuir as complicações.JUSTIFICATIVA Y OBJETIVOS: La analgesia promovida por la infusión peridural de anestésico local con analgésicos opioides es reconocidamente de buena calidad y con pocos efectos adversos. El objetivo de este estudio fue determinar el número, formas y gravedad de las complicaciones pós-operatorias relacionadas a la analgesia peridural y a la inserción del catéter peridural. MÉTODO: Fueron evaluados, retrospectivamente, 469 pacientes sometidos a la analgesia peridural pós-operatoria entre 18/10/1999 y 18/10/2001. La analgesia peridural fue conducida usándose solución de bupivacaína 0,1% con fentanil (1 a 5 µg.ml-1, iniciándose la infusión a 3 ml.h-1. La velocidad de infusión era ajustada de acuerdo con la queja álgica del paciente. Fueron analizadas las siguientes variables: la duración de la infusión peridural; la ocurrencia de efectos adversos y complicaciones, relacionándolos a los datos demográficos, tipo de cirugía y posición del catéter peridural; y la calidad de la analgesia obtenida con la técnica (escala analógico-visual de dolor e índice de satisfacción del paciente. RESULTADOS: Los catéteres peridurales permanecieron implantados por una media de 2,2 días, variando de 6 horas a 10 días, y el índice global de complicaciones relacionadas a la técnica fue de 46,3%, siendo que la mayoría fue de pequeña magnitud, sin repercusión clínica. De estas, 13,9% estaban relacionadas directamente al catéter peridural (desconección, exteriorización, dolor lumbar, inflamación e infección local. Otras complicaciones más comunes fueron encontradas: vómitos y retención urinaria. La analgesia pós-operatoria fue efectiva con 97,2% de los pacientes refiriendo satisfacción con la técnica. Pacientes sin dolor o con dolor leve, en el primero, segundo y tercero días de pós-operatorio, constituyeron, respectivamente, 80

  13. The International intraval project. Phase 1, case 7. The Pocos de Caldas natural analogue: studies of redox front movement

    International Nuclear Information System (INIS)

    Chapman, N.

    1992-01-01

    The study of natural analogues is an important means of validating models of the geochemical processes affecting radionuclide behaviour. This test case, which is one aspect taken from the much broader geochemical studies carried out in the Pocos de Caldas Project, concerns the nature and behaviour of redox fronts, such as might be generated in the near-field of a spent-fuel repository. A redox front is potentially important in terms of the movements and speciation of certain radionuclides close to the waste package. The natural redox fronts in Osamu Utsumi uranium mine display many of the features which may occur in a repository, and influence the movement of natural series radionuclides, and other elements, through the rock/groundwater system. This report, describes the geological, hydrogeological and geochemical nature of the site, and of the redox fronts. Emphasis is placed on the mineralogy of the fronts, and the concentration profiles of various elements across them. The project involved a number of different modelling approaches which attempted to describe the generation and movement of the fronts through the rock. These included mass balance, reaction-diffusion models, fissure flow models, thermodynamic models, and kinetic models. 21 refs., 36 figs., 1 tab

  14. Behavior of 226Ra in the aquatic environment of the uranium mine region of Pocos de Caldas, MG, Brazil

    International Nuclear Information System (INIS)

    Silva Amaral, E.C. da.

    1979-08-01

    A sampling and analytical program for 238 U, 226 Ra and 210 Pb was started, at first, in the uranium mine region, at Pocos de Caldas, MG, Brazil. Afterwards, the interaction was studied between 226 Ra and local river sediments and waters. Peliminary studies were also done on the mobility of 226 Ra retained on solid matter or soil, induced by local waters. Above normal concentrations of 238 U, 226 Ra and 210 Pb were found in local waters, sediments and plants collected on the imediate vicinity of the mine. 226 Ra distribution coefficients are on the order of 10 3 for the different samples assayed. It was concluded that, in the future, 226 Ra discharged into liquid environment should be only temporarily retained by sediments. Its transport by surface waters should be predominantly in the soluble form. 226 Ra should become the critical radionuclide in terms of internal radiation dose on the local population, due to its ingestion with water. 226 Ra retained on solid supports is mobilized by local waters and its solubilization is dependent on the volume of water passed through. (M.A.) [pt

  15. Fibroadenoma with "immature-like" type of usual ductal hyperplasia.

    Science.gov (United States)

    Bezić, Joško; Karaman, Ivana; Kunac, Nenad

    2016-01-01

    We herein report a case of the breast fibroadenoma with foci of so-called immature variant of the conventional ductal hyperplasia. This type of usual ductal hyperplasia is histologically characterised by encircling intraductal proliferation of large cells with pale to amphophilic cytoplasm and large nuclei which vary in shape and in staining quality of the chromatin. We showed here, using the cytokeratin immunohistochemistry, that the proliferating cells were not of immature but rather mature immunohistochemical phenotype. Because of the presented discordance between immature histology and mature immunohistological profile we suggest that this rare type of usual ductal hyperplasia should be called "immature-like".

  16. Un poco de Matemagia

    Directory of Open Access Journals (Sweden)

    José Mª Navas

    2012-10-01

    Full Text Available Junto a los clásicos juegos de manipulación, para los que se necesita una considerable habilidad manual, hay otra rama del ilusionismo que se basa en procedimientos más sutiles, entre los que están cogiendo auge en los últimos años los que parten de conceptos matemáticos, algunos enormemente simples, otros de cierta complejidad. Así nació lo que ha dado en llamarse Matemagia.

  17. Acid drainages of the pyritic sterile from the Pocos de Caldas uranium mine: environmental interpretation and implications; Drenagens acidas do esteril piritoso da mina de uranio de Pocos de Caldas: interpretacao e implicacoes ambientais

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Vicente Paulo de

    1995-12-01

    Considering the planned closure of the first uranium mine and milling plant operating in Brazil, located in the Pocos de Caldas Plateau, in the State of Minas Gerais, in the next two years, there is the need to obtain basic information for its decommissioning. Special attention has been directed to the following critical areas: open pit, tailing, dam and waste rock piles, because these are the main sources of acid drainage generation. These waters cannot be allowed to flow in the external environment because in addition to sulphuric acid, there is a number of elements in concentration above those allowed by regulations. Among the waste piles (bota-foras BF) two of them BF-4 and BF-8, are in a process of acid generation, thus requiring more attention. The objective of this work was to simulate at the laboratory scale the oxidation and the reduction zones of BF-4. The experiments were conducted in acrylic columns, where the waste sample was kept under aerated and saturated conditions, in different columns. The control of the chemical (solubilized chemical species), physico-chemical (redox potential, pH, conductivity) and biological (bacterial activity) parameters has been carried out on the acid solutions generated by the chemical and biological reactions that occur at the waste. Although the results refer to a four month period, some relevant points can be highlighted, which will serve as a basis for further research. The mineralogical characterization identified the existence of other sulphides associated to pyrite with lower oxidation potential than the latter. The results obtained with the biological characterization for the two conditions studied revealed that the bacterial activity is more intense in the region in contact with air, than in saturated region. (author) 30 refs., 29 figs., 8 tabs.

  18. Association of usual intake of added sugars with nutrient adequacy

    Science.gov (United States)

    Recommendations for intakes of added sugars have varied considerably and the scientific basis supporting these recommendations has been inconsistent. The goal of this study was to examine the association of usual intake (UI) of added sugars and nutrient adequacy in those participating in NHANES 2009...

  19. Recirculation usually precedes malignant edema in middle cerebral artery infarcts

    DEFF Research Database (Denmark)

    Nielsen, T H; Ståhl, N; Schalén, W

    2012-01-01

    In patients with large middle cerebral artery (MCA) infarcts, maximum brain swelling leading to cerebral herniation and death usually occurs 2-5 days after onset of stroke. The study aimed at exploring the pattern of compounds related to cerebral energy metabolism in infarcted brain tissue....

  20. Acid drainages of the pyritic sterile from the Pocos de Caldas uranium mine: environmental interpretation and implications

    International Nuclear Information System (INIS)

    Souza, Vicente Paulo de

    1995-12-01

    Considering the planned closure of the first uranium mine and milling plant operating in Brazil, located in the Pocos de Caldas Plateau, in the State of Minas Gerais, in the next two years, there is the need to obtain basic information for its decommissioning. Special attention has been directed to the following critical areas: open pit, tailing, dam and waste rock piles, because these are the main sources of acid drainage generation. These waters cannot be allowed to flow in the external environment because in addition to sulphuric acid, there is a number of elements in concentration above those allowed by regulations. Among the waste piles (bota-foras BF) two of them BF-4 and BF-8, are in a process of acid generation, thus requiring more attention. The objective of this work was to simulate at the laboratory scale the oxidation and the reduction zones of BF-4. The experiments were conducted in acrylic columns, where the waste sample was kept under aerated and saturated conditions, in different columns. The control of the chemical (solubilized chemical species), physico-chemical (redox potential, pH, conductivity) and biological (bacterial activity) parameters has been carried out on the acid solutions generated by the chemical and biological reactions that occur at the waste. Although the results refer to a four month period, some relevant points can be highlighted, which will serve as a basis for further research. The mineralogical characterization identified the existence of other sulphides associated to pyrite with lower oxidation potential than the latter. The results obtained with the biological characterization for the two conditions studied revealed that the bacterial activity is more intense in the region in contact with air, than in saturated region. (author)

  1. Microbiological analysis at the Osamu Utsumi mine and Morro do Ferro analogue study sites, Pocos de Caldas, Brazil

    International Nuclear Information System (INIS)

    West, J.M.; Vialta, A.; McKinley, I.G.

    1990-01-01

    The Pocos de Caldas project is a wide-ranging natural analogue study focussed on a number of areas of concern in the performance assessment of the disposal of radioactive waste. Part of the work has involved characterising microbial populations and their influence in various processes. Core material and groundwaters have been sampled for microbiological content at various depths form boreholes at the Osamu Utsumi open pit uranium mine and Morro do Ferro Th/REE ore body. Microbes were found in all samples but numbers do not appear to be related to depth. Analyses of groundwaters gave higher numbers than with solid material and demonstrated the presence of sulphur cycle bacteria. These observations have been compared with predictions of a model used in performance assessment to calculate the maximum biomass/microbial activity based on constraints set by available nutrients and energy. The main conclusions of this analysis are: 1. Low microbial activities can be supported by the energy and nutrients supplied by alteration processes at or around the redox front. The maximum annual production of approximately equal to 0.01 - 0.1 g biomass (dry)/m 2 of redox front is in reasonable agreement with observed standing populations. 2. The presence of high concentrations of sulphate reducing bacteria around the redox front indicate a complex sulphur geochemistry which may be predominantly microbially catalysed and could explain the nodular form of pitchblende concretions and the presence of secondary pyrite. 3. There is little trace element mobilisation by organic byproducts and the main role of microbes in this system is to catalyse specific redox reactions. (au)

  2. Complicaciones maternas en adolescentes y adultas afiliadas al régimen subsidiado, 2012 / Maternal Complications in Adolescents and Adults Affiliated to the subsidized regime, 2012

    Directory of Open Access Journals (Sweden)

    Lina M. Díaz B.

    2015-09-01

    Full Text Available RESUMEN La intervención de las complicaciones maternas y la minimización de sus efectos en la salud materno-infantil es prioridad para el cuidado en salud de esta población. La identificación de factores asociados a la complicación materna es de vital importancia para definir políticas y estrategias de intervención de esta problemática. Objetivo: determinar los factores asociados a complicaciones durante el tercer trimestre del embarazo, parto y puerperio de las maternas pertenecientes al régimen subsidiado atendidas en una institución de segundo nivel de complejidad de Medellín. Metodología: investigación de cohorte ambiespectivo, que tiene como factor de exposición la edad (expuesto: adolescentes entre 14 y 19 años, no expuesto: entre 20 y 34 años de edad y la complicación materna. Se calcularon frecuencias absolutas y relativas para las variables cualitativas y media, mediana y rango intercuartílico para las variables cuantitativas, se calculó proporción de incidencia de las complicaciones y el riesgo relativo crudo y ajustado por variables de confusión. Resultados: el principal factor de riesgo asociado a complicación materna fue la atención prenatal inadecuada (criterio de Kessner. Se encontró como factor protector la asistencia al curso psicoprofiláctico. Conclusión: no se encontraron grandes diferencias entre la población adolescente y adulta, pero sí se identificaron aspectos sociales (relaciones familiares, educacionales y de atención en salud que pueden afectar la salud materna de la población del régimen subsidiado atendida por una institución de segundo nivel de complejidad./ Abstract The intervention of maternal complications and the minimization of its impact on mother and child health is a priority for this population's health care. Identifying factors associated with maternal complications is critical to devising policies and intervention strategies against this problem. Objective: to determine the

  3. Humanistic therapies versus treatment as usual for depression

    Science.gov (United States)

    Davies, Philippa; Hunot, Vivien; Moore, Theresa HM; Caldwell, Deborah; Jones, Hannah; Lewis, Glyn; Churchill, Rachel

    2014-01-01

    This is the protocol for a review and there is no abstract. The objectives are as follows: To examine the effectiveness and acceptability of all humanistic therapies compared with treatment as usual/waiting list/attention placebo control conditions for acute depression.To examine the effectiveness and acceptability of different humanistic therapy models (person-centred, gestalt, process-experiential, transactional analysis, existential and non-directive therapies) compared with treatment as usual/waiting list/attention placebo control conditions for acute depression.To examine the effectiveness and acceptability of all humanistic therapies compared with different types of comparator (standard care, no treatment, waiting list, attention placebo) for acute depression. PMID:25408624

  4. Complicaciones de las otitis medias agudas y crónicas en el niño Complications of acute and chronic otitis media in the child

    Directory of Open Access Journals (Sweden)

    Julianis Loraine Quintero Noa

    2013-03-01

    Full Text Available Gracias al descubrimiento de los antibióticos, la incidencia de complicaciones en las otitis medias agudas y crónicas ha descendido significativamente, aunque continúan siendo un peligro potencial de morbilidad y mortalidad. La disminución de las complicaciones puede condicionar retrasos diagnósticos por falta de sospecha clínica, enmascaramiento por tratamientos antibióticos previos y mal pronóstico, por lo cual siguen siendo procesos graves que ponen en peligro la vida del enfermo. Se definen actualmente con igual sistema de clasificación: extracraneales e intracraneales. Las primeras se subdividen en extratemporal e intratemporal, y constituyen un problema de salud en la población pediátrica a pesar del uso extendido de antibióticos. La evaluación clínico-otomicroscópica e imaginológica se reporta como criterio diagnóstico predictivo de sospecha y de confirmación. La parálisis facial, el vértigo, los vómitos, la cefalea, el dolor irradiado a la mastoides o a la región temporoparietal, y la hipertermia, deben alertar al médico sobre la presencia de una complicación supurada.Thanks to the discovery of antiobiotics, the incidence of complications in the chronic and acute otitis media has significantly decreased, though they remain a potential mortality and morbidity risk. The reduction of complications can be conditional on some diagnostic delays, on account of lack of clinical suspicions, symptoms disguised by previous antibiotic treatments and wrong prognosis; therefore, the complications continue to be severe processes that endanger the patient's life. They are currently classified as extracranial and intracranial. The former are divided into extratemporal and intratemporal and represent a health problem for the pediatric population despite the extended use of antibiotics. The clinical, otomicroscopic and imaging assessment is reported as a diagnostic criterion predictive of suspicions and of confirmation. Facial

  5. Water quality and toxicity of river water downstream of the uranium mining facility at Pocos de Caldas, MG, Brazil

    International Nuclear Information System (INIS)

    Lauria, Dejanira C.; Vascocnellos, Luisa M.H.; Simoes, Francisco F. Lamego; Clain, Almir F.; Scassiotti, Walter F.; Antunes, Ivan; Ferreira, Ana M.; Nascimento, Marcos R.L.

    2009-01-01

    The uranium mining site of Pocos de Caldas consists of open mine pit, tailings, waste rock dumps and an acid rock drainage problem, which has the potential to impact upon freshwater of the Ribeirao das Antas catchment. The high level of manganese (value of 1.8 mg/L) contained in the discharge water (DW) is an important factor affecting the water quality of the river (water quality criterion for aquatic life for Mn is 0.1 mg/L). Water quality criteria (WQC) are used for regulatory purpose and intended to define concentrations of chemicals in water that are protective of aquatic life and human health. WQC is a standard, although it is recognized that in some instances these criteria may be overprotective as metal bioavailability and hence toxicity is dependent on water chemistry. The toxicity assessment of WD was performed by bioassays with Daphnia similis and Ceriodaphnia dubia as bioindicators. As DW showed no toxicity to the organisms and the chemical analysis and dose assessments pointed U and Mn as the most important metals for water toxicity, the U and Mn toxicities were evaluated in the DW spiked with U and Mn. Acute uranium toxicity (48 h immobilisation test) for Daphnia similis was determined as a LC50 value (concentration that is toxic to 50% of test organisms) around 0.05-0.06 mg/L, value close to the one found for effects on reproduction, a 7 day LOEC (lowest observed effect concentration) of 0.062 mg/L for Ceriodaphnia dubia. The value of NOEC (no-observed effect concentration) for U was 0.03 mg U/L, which is higher than the concentration corresponded to the authorized dose limit for 238 U (0.004 mg/L) and higher than the uranium WQC (0.02 mg U/L). The manganese concentration in the DW is lower than the found value of LC50 (11.5 mg/L), LOEC (10 mg/L) and NOEC (5 mg Mn/L). (author)

  6. Complicaciones obstétricas y médicas en el Trastorno de Déficit Atencional/Hiperactividad (TDAH: ¿hay diferencias entre los subtipos?

    Directory of Open Access Journals (Sweden)

    Connie Capdevila-Brophy

    2007-01-01

    Full Text Available El debate actual sobre los subtipos de Trastorno de Déficit Atencional/ Hiperactividad (TDAH se centra en determinar si las similitudes y diferencias halladas en la sintomatología asociada aportan evidencia para conceptualizar los subtipos como manifestaciones de distinto trastorno. El objetivo de este estudio retrospectivo ex post facto es investigar las diferencias entre los subtipos de TDAH con predominio de inatención (TDAH-I (n = 20 y TDAH combinado (TDAH-C (n = 39 en su historia prenatal, perinatal, del primer año y los problemas médicos posteriores. Los resultados indican que ambos subtipos presentan índices elevados de complicaciones obstétricas y problemas médicos. El subtipo TDAH-I se asocia con hemorragias prenatales, infecciones de oído y alergias, y el TDAH-C con cólicos del lactante y lesiones con sutura. La principal conclusión sugiere que las noxas de curso más continuo o dilatadas en el tiempo estarían más presentes en el grupo TDAH-I mientras que algunas características en el primer año y las lesiones que requieren suturas estarían más asociadas al subtipo TDAH-C.

  7. Auscultation of Velcro Crackles is Associated With Usual Interstitial Pneumonia.

    Science.gov (United States)

    Sellarés, Jacobo; Hernández-González, Fernanda; Lucena, Carmen M; Paradela, Marina; Brito-Zerón, Pilar; Prieto-González, Sergio; Benegas, Mariana; Cuerpo, Sandra; Espinosa, Gerard; Ramírez, José; Sánchez, Marcelo; Xaubet, Antoni

    2016-02-01

    Auscultation of Velcro crackles has been proposed as a key finding in physical lung examination in patients with interstitial lung diseases (ILDs), especially in idiopathic pulmonary fibrosis (IPF). However, no studies have been carried out to assess the association of Velcro crackles with other clinical variables.We evaluated a cohort of 132 patients, prospectively and consecutively included in our ILD diagnostic program at a tertiary referral center. All patients were auscultated during the physical examination. The patients were divided into 2 groups: "presence" or "nonpresence" of bilateral Velcro crackles.Of all patients assessed, 83 (63%) presented Velcro crackles in the respiratory auscultation. Patients with Velcro crackles usually had more frequently cough and dyspnea at the moment of diagnosis. Forced vital capacity (P = 0.002) and lung diffusion capacity for carbon monoxide (P = 0.04) was lower in these patients. The ILD-GAP index was higher in the group with Velcro crackles (P = 0.01). All patients with usual interstitial pneumonia (UIP) in high-resolution computed tomography and all patients with final IPF diagnosis presented Velcro crackles. In multivariate analysis, the presence of Velcro crackles was independently associated with an UIP pattern.In patients suspected of having ILD, the auscultation of Velcro crackles was associated with UIP, a possibility which must be taken into consideration in early ILD detection in primary care.

  8. Unusual behaviour of usual materials in shock waves

    International Nuclear Information System (INIS)

    Kanel, G I

    2014-01-01

    Exotic results of investigations of inelastic deformation and fracture under shock wave loading are presented and briefly discussed. Temperature effects on the flow stress at high strain rate may differ even in sign from those we observe at low and moderate strain rates. Investigations of the temperature-rate dependence of the yield stress at shock compression demonstrate intense multiplication of dislocations. At the highest strain rates, so-called ideal (ultimate) shear and tensile strength is reached in experiments with picosecond durations of shock loading. Although grain boundaries, in general, reduce resistance to fracture as compared to single crystals, the spall strength of ultra-fine-grained metals usually slightly exceeds that of coarse-grain samples. Failure wave phenomena have been observed in shock-compressed glasses.

  9. Consolidity: Moving opposite to built-as-usual systems practices

    Directory of Open Access Journals (Sweden)

    Hassen Taher Dorrah

    2013-06-01

    Full Text Available With the recent uncovering of the mystery of consolidity as an inner property of systems, it is demonstrated that this notion is an indispensable pillar of systems modeling, analysis, design and building. Based on the opposite mathematical relation between consolidity versus stability and controllability, a new conceptual life cycle (change pathway graph for natural and man-made built-as-usual systems is presented and thoroughly discussed. For the conceptual cycle development progress, it is logically conceived that system behavior changes rate has not accidentally happened, but is relatively influenced at the point of progress by the associated direct system consolidity index corresponding to the acting on-the-spot varying environments or effects. Such conceptual graph represents a real research advancement indicating that we have to move opposite to current systems building practices for solving many real life enigmatic problems. It is illustrated using stabilization of inverted pendulum problem that it is amenable by cleverly manipulating systems structure and parameters to attain new designed systems with aggregates of superiority of consolidity, stability and controllability principle. It is recommended that we have to seek new generation of innovative non-conventional systems structures moving opposite to conventional built-as-usual system practices that can enable providing directly such three aggregates of superiority requirements as their built-in self property. This will open the door towards solving many real life challenging dilemmas in various sciences and disciplines, such as engineering, space sciences, medicine, pharmacology, biology, ecology, life sciences, economy, operations research, humanities and social sciences that are believed to be attributed due to their systems inferior consolidity.

  10. Porfirias poco frecuentes: Casos detectados en la población argentina Non frequent porphyrias in the argentinean population

    Directory of Open Access Journals (Sweden)

    V A Melito

    2006-12-01

    Full Text Available Las porfirias son consecuencia de fallas en el metabolismo del hemo. Se clasifican según el tipo de sintomatología clínica prevalente o el órgano donde se expresa preferencialmente la falla metabólica. En general la deficiencia enzimática está asociada a mutaciones en los genes que codifican para cada una de las enzimas. Están descritos 7 tipos de porfiria diferentes. Se transmiten por carácter autosómico dominante a excepción de la PCE, la PHE y la NPA que son recesivas. Sin embargo, están reportadas variantes homocigotas para el resto de las porfirias de pronóstico y evolución mucho más grave que la forma heterocigota. La descripción de estos casos poco frecuentes, sus tratamientos y evolución, facilitarían tanto el diagnóstico diferencial de la porfiria como el conocimiento de las posibilidades terapéuticas en cada caso. Asimismo para las porfirias heterocigotas con manifestación infantil, su identificación temprana y tratamiento aseguraría una mejor evolución minimizando los riesgos asociados. Se han diagnosticado 5 casos de porfirias agudas en niñas: 2 de PAI, 2 de PV y 1 de CPH. Entre las porfirias cutáneas se presentan 25 casos de PCT infantil, el primer caso de PHE en Argentina, 4 casos de PCE infantil y 1 en un adulto y 2 casos de PPE con compromiso hepatobiliar.The Porphyrias are a group of diseases resulting from partial deficiencies in one of the heme biosynthetic enzymes. These disorders can be classified on the basis of their clinical manifestations or according the organ where the metabolic deficiency is mainly expressed. In general this enzyme deficiency is associated with mutations in the genes which codify each enzyme. There are 7 types of Porphyrias. They are autosomal dominant disorders with the exception of PCE, PHE and NPA which are recessive. However, some rare and severe cases with recessive inheritance have also been reported. The description of these infrequent cases and their treatments and

  11. Complicaciones multiorgánicas de origen tardío secundarias a lesiones por descarga eléctrica, reporte de un caso

    Directory of Open Access Journals (Sweden)

    Gary Caballero García

    2013-11-01

    Full Text Available Title: Late complications of origin multiorgan secondary injuries electric shock, report of a case.ResumenTeniendo en cuenta el gran número de lesiones y muertes ocasionadas por energía eléctrica, se revisarán las secuelas que pueden acontecer posteriores a dicho suceso, dado que la electricidad daña los tejidos al transformarse en energía térmica mediante la destrucción de la integridad de la membrana celular. El caso clínico trata de un paciente de 31 años de edad quien hace siete años recibió una descarga eléctrica de 440 voltios, y en su evolución ha presentado diversas complicaciones multiorgánicas: Neuropatía periférica tipo dolor neuropático, alteración estructural de la vía aferente sensorial visual, entre otras. (DUAZARY 2013 No. 1, 51 - 55AbstractGiven the large number of injuries and deaths caused by electricity, a review of the consequences that can happen after that event, given that electricity damages tissue by transforming into heat energy by destroying the integrity of the cell membrane. The clinical case is a 31 years old pacient who seven years ago received an electric shock of 440 volts, and their evolution has presented various multiorgan complications: Neuropathic pain Peripheral neuropathy type, structural alteration of the visual sensory afferent pathway, among others.Keywords: Burns; Electric; Chronic Pain; Complications; Rehabilitation. Source: Medical Subjet Headings (MeSH.

  12. Not the usual suspects: addressing layers of vulnerability.

    Science.gov (United States)

    Luna, Florencia; Vanderpoel, Sheryl

    2013-07-01

    This paper challenges the traditional account of vulnerability in healthcare which conceptualizes vulnerability as a list of identifiable subpopulations. This list of 'usual suspects', focusing on groups from lower resource settings, is a narrow account of vulnerability. In this article we argue that in certain circumstances middle-class individuals can be also rendered vulnerable. We propose a relational and layered account of vulnerability and explore this concept using the case study of cord blood (CB) banking. In the first section, two different approaches to 'vulnerability' are contrasted: categorical versus layered. In the second section, we describe CB banking and present a case study of CB banking in Argentina. We examine the types of pressure that middle-class pregnant women feel when considering CB collection and storage. In section three, we use the CB banking case study to critique the categorical approach to vulnerability: this model is unable to account for the ways in which these women are vulnerable. A layered account of vulnerability identifies several ways in which middle-class women are vulnerable. Finally, by utilizing the layered approach, this paper suggests how public health policies could be designed to overcome vulnerabilities. © 2013 John Wiley & Sons Ltd.

  13. Risk management in environmental pollution: a case study of the uranium mining and milling facilities at Pocos de Caldas, Minas Gerais, Brazil

    International Nuclear Information System (INIS)

    Fernandes, H.M.; Prado, V.C.S.; Veiga, L.H.S.; Amaral, E.C.S.; Freitas, P.; Bidone, E.D.

    1993-01-01

    Environmental risk management concept was adapted to uranium mining and milling facilities at Pocos de Caldas, Minas Gerais, Brazil. Environmental radionuclide and metal concentration in surface waters, efficiency of the effluent treatment were evaluate. The data shows that the effluent treatment was effective to reduce pollutant releases in the environment but the benefit in the dose reduction may be questioned. In addition it's stressed the necessity of a metal exposure assessment due to vegetables consumption that has never been developed in that region. (B.C.A.). 07 refs, 02 figs, 02 tabs

  14. The Glycoprofile Patterns of Endothelial Cells in Usual Interstitial Pneumonia

    Directory of Open Access Journals (Sweden)

    A Barkhordari

    2014-09-01

    Full Text Available [THIS ARTICLE HAS BEEN RETRACTED FOR DUPLICATE PUBLICATION] Background: The pathological classification of cryptogenic fibrosing alveolitis has been a matter of debate and controversy for histopathologists. Objective: To identify and specify the glycotypes of capillary endothelial cells in usual interstitial pneumonia (UIP compared to those found in normal tissue. Methods: Sections of formalin-fixed, paraffin-embedded blocks from 16 cases of UIP were studied by lectin histochemistry with a panel of 27 biotinylated lectins and an avidin-peroxidase revealing system. Results: High expression of several classes of glycan was seen de novo in capillary endothelial cells from patients with UIP including small complex and bi/tri-antennary bisected complex N-linked sequences bolund by Concanavalin A and erythro-phytohemagglutinin, respectively, GalNAca1 residues bound by Helix pomatia and Maclura pomifera agglutinins, and L-fucosylated derivatives of type II glycan chains recognized by Ulex europaeus agglutinin-I. Glycans bound by agglutinins from Lycopersicon esculentum (β1,4GlcNAc and Wisteria floribunda (GalNAc as well as GlcNAc oligomers bound by Phytolacca americana and succinylated Wheat Germ agglutinin were also seen in the capillary endothelial cells of UIP. In contrast, L-fucosylated derivatives of type I glycan chains were absent in cells from cases of UIP when Anguilla anguilla agglutinin was applied, unlike the situation in normal tissue. Conclusion: These results may indicate existence of two distinct populations of endothelial cell in UIP with markedly different patterns of glycosylation, reflecting a pattern of differentiation and angiogenesis, which is not detectable morphologically.

  15. Complications of endoscopic retrograde cholangiopancreatography: A study in a small ERCP unit Complicaciones de la colangiopancreatografía retrógrada endoscópica: Estudio en una unidad pequeña de CPRE

    Directory of Open Access Journals (Sweden)

    J García-Cano Lizcano

    2004-03-01

    procedimiento consolidado para el drenaje de la vía biliar y pancreática, que, sin embargo, conlleva complicaciones. El número parece ser mayor en los centros que realizan menos de 200 CPRE anuales. No obstante, en ocasiones, la distribución de los recursos sanitarios hace preciso realizar esta técnica en centros con menor número de procedimientos. Presentamos la experiencia de las complicaciones de la CPRE en una unidad pequeña. Material y métodos: estudio retrospectivo sobre unos datos recogidos de forma prospectiva durante seis años (1997-2002. En este periodo, dos endoscopistas, trabajando conjuntamente, han realizado 507 CPRE, lo que corresponde a una media aproximada de 84 procedimientos anuales. Resultados: en las 507 CPRE se produjeron 55 complicaciones (10,85% y como consecuencia de ellas, cuatro pacientes fallecieron (0,79%. Hubo 28 pancreatitis (5,5%, 8 hemorragias postesfinterotomía (1,6%, 7 perforaciones bilioduodenales (1,4%, 8 sepsis de origen biliar (1,6% y otras 4 complicaciones varias. Las CPRE con éxito diagnóstico y terapéutico -cuando se precisó- fueron 418 (82,4%, y presentaron 46 (11% complicaciones. Hubo 89 (17,6% CPRE con fallo diagnóstico o terapéutico, que presentaron 9 (10,11% complicaciones (p=0,8 entre ambos grupos. Treinta y cinco (7% CPRE fueron exclusivamente diagnósticas, presentando 6 (17% complicaciones. Las 187 CPRE realizadas para extraer coledocolitiasis, con 14 (7,4% complicaciones, fueron el grupo con menor morbilidad (p=0,04. Conclusiones: la tasa de complicaciones en nuestro centro se encuentra dentro de los rangos publicados. La extracción de coledocolitiasis fue el grupo de CPRE con menos complicaciones. Por su morbilidad, debe valorarse cuidadosamente el riesgo-beneficio de las exploraciones que se prevean exclusivamente diagnósticas.

  16. Steam injections wells: topics to consider in casing design of steam injection wells; Revestimento para pocos de vapor

    Energy Technology Data Exchange (ETDEWEB)

    Conceicao, Antonio Carlos Farias [PETROBRAS, Recife, PE (Brazil). Gerencia de Perfuracao do Nordeste. Div. de Operacoes

    1994-07-01

    Steam injection is one of the processes used to increase production from very viscous oil reservoirs. A well is completed at a temperature of about 110 deg F and during steam injection that temperature varies around 600 deg F. Strain or breakdowns may occur to the casing, due to the critical conditions generated by the change of temperature. The usual casing design methods, do not take into account special environmental conditions, such as those which exist for steam injection. From the results of this study we come up to the conclusion that casing grade K-55, heavy weight with premium connections, without pre-stressing and adequately heated, is the best option for steam injection well completion for most of the fields in Brazil. (author)

  17. Evaluación del optimismo disposicional en pacientes en hemodiálisis y su relación con las complicaciones

    Directory of Open Access Journals (Sweden)

    Isabel Luque Cantarero

    2014-12-01

    Full Text Available Introducción: El optimismo parece tener una influencia sobre la resistencia a la enfermedad y de la mejora de la salud en pacientes con problemas cardíacos, respiratorios y oncológicos. Sin embargo, son escasos los estudios en pacientes en con enfermedad crónica renal en hemodiálisis; de ahí el interés de nuestro estudio. Objetivo: El objetivo de este estudio fue analizar la relación entre el grado de optimismo disposicional con las complicaciones y la calidad de vida percibida en un grupo de pacientes de hemodiálisis. Pacientes y Métodos: Se estudiaron 78 pacientes en HD, del servicio de Nefrología de Córdoba. Se realizó un estudio observacional analítico. Se evaluaron variables demográficas, tiempo en diálisis, índice de comorbilidad de Charlson, centro de diálisis, acceso vascular, optimismo disposicional mediante el LOT-R (a mas puntuación más optimismo, calidad de vida relacionada con la salud mediante láminas COOP-WONCA (a mas puntuación peor calidad de vida percibida y número de ingresos en el año anterior. Resultados: La edad media fue 64.8±17.1 años. El 38.5% eran mujeres y el 61.5% hombres. La mediana del número de ingresos en el último año fue de 1 (rango: 0-10. La mediana del índice de comorbilidad fue 7 (rango 0-12. La media del LOT-R fue 20.76±4.8 y la mediana 21 (rango: 8-29. Se estableció la mediana del LOT-R, como punto de corte para clasificar a los pacientes como optimistas (>21 de mediana y pesimistas (<21. Al comparar ambos grupos (optimistas frente a pesimistas se encontraron diferencias significativas para el COOP-WONCA (19.8±5.6 frente a 24.5±6.6, p<0.002. Sin embargo no se encontraron diferencias para el número de ingresos, ni para el índice de comorbilidad, entre ambos grupos. Conclusiones: No se encontró relación entre optimismo disposicional y número de ingresos, ni comorbilidad asociada. Sin embargo, los más optimistas tienen mayor de calidad de vida percibida relacionada con

  18. Conocimientos de los médicos sobre enfermedad periodontal y su relación con complicaciones en el embarazo

    Directory of Open Access Journals (Sweden)

    Martha Juliana Rodríguez

    2013-12-01

    Full Text Available Introducción: Estudios recientes han vinculado a las enfermedades bucales con condiciones sistémicas. Específicamente, la enfermedad periodontal se ha relacionado con parto pretérmino, bajo peso al nacer y preclampsia. Objetivo: Evaluar los conocimientos y las prácticas de los médicos generales y ginecobstetras sobre la enfermedad periodontal y su relación con complicaciones del embarazo. Metodología: Se realizó un estudio de corte transversal en una muestra de 139 médicos generales y 24 ginecobstetras. Se aplicó un cuestionario de autoreporte, se calcularon frecuencias y proporciones para las variables cualitativas, promedios y desviaciones estándar para las cuantitativas. Para establecer las diferencias entre los grupos se realizó la prueba de Chi cuadrado, el test exacto de Fisher, la prueba t de Student y la U. de Mann Whitney según la naturaleza y distribución de las variables. Resultados: El 66,9% (93 de los médicos generales y el 75,0% (18 de los ginecobstetras consideraron que la enfermedad periodontal podría ser un factor de riesgo para la salud de la madre y su hijo. Así mismo, el 30,7% (42 de los médicos generales y el 45,8% (11 de los ginecobstetras relacionaron a la enfermedad periodontal con el parto pretérmino, bajo peso al nacer y preclampsia. A pesar de estos hallazgos, sólo el 77,4% (106 de los médicos y el 54,2% (13 de los ginecobstetras "siempre" remitían a la gestante a consulta odontológica. Conclusión: Aunque los participantes tenían conocimientos sobre los tópicos evaluados, hace falta una mayor aplicación de los mismos para asegurar el bienestar del binomio madre e hijo.

  19. Complicaciones asociadas al catéter percutáneo en recién nacidos pretérmino y a término.

    Science.gov (United States)

    Higareda-Almaraz, Martha Alicia; Gutiérrez-Monraz, Paz Alejandra; Castillo-Sánchez, Ruth Alejandrina; León, Juan Carlos Barrera-de; Zavalza-Gómez, Ana Bertha; Higareda-Almaraz, Enrique

    2018-01-01

    Identificar las complicaciones asociadas al catéter percutáneo en recién nacidos pretérmino y a término. Estudio transversal comparativo. Se incluyeron recién nacidos que tenían insertado un catéter percutáneo, con resultados de cultivo de sangre y segmento distal del catéter. Se formaron dos grupos: pretérmino y a término. Se calcularon la razón de momios (RM) y el intervalo de confianza del 95% (IC 95%). Se analizaron datos de 50 recién nacidos por grupo. En los pretérmino y a término se encontró un valor de la media de edad gestacional de 30 ± 3 y 40 ± 2, respectivamente (p = 0.01), y unos porcentajes de sepsis por catéter del 36 y el 18% (p = 0.02; RM: 2.56; IC 95%: 1.02-7.17), de catéter infectado del 50 y el 22% (p = 0.01; RM: 5.92; IC 95%: 1.66-23.12), de catéter colonizado del 24 y el 14% (p = 0.01; RM: 3.58; IC 95%: 1.32-9.90), de infección local del 14 y el 8% (p = 0.03; RM: 1.87; IC 95%: 1.45-8.29), de infiltración del 18 y el 4% (p = 0.02; RM: 5.27; IC 95%: 1.17-59), de retiro accidental del 6 y el 22% (p = 0.02; RM: 0.23; IC 95%: 0.05-0.87) y de rotura del catéter del 10 y el 28% (p = 0.02; RM: 0.29; IC 95%: 0.08-0.98). Se encontró mayor asociación de infecciones e infiltraciones por catéter percutáneo en los pretérmino, y de retiro accidental y rotura del catéter en los nacidos a término. Copyright: © 2018 SecretarÍa de Salud

  20. Well test: production analysis and allocation measurement; Teste de poco: analise da producao e medicao de apropriacao

    Energy Technology Data Exchange (ETDEWEB)

    Geron, Luis Carlos [Smar Equipamentos Industriais Ltda., Sertaozinho, SP (Brazil). Dept. de Engenharia Aplicacoes; Tateishi, Sergio Hideki [Smar Equipamentos Industriais Ltda, Sertaozinho, SP (Brazil). Dept. de Pesquisa e Desenvolvimento

    2008-07-01

    The well test is an instrument frequently used to evaluate the production capacity of wells and it usually has specific requirements in the flow measurement, that are not necessary in the flow measurement system for custody transfer applications. Starting with the requirement to measure the injected product in the well when it is in the recuperation phase and it also includes compliance to specific standards for allocation measurement, because these hydrocarbon products are not treated as well as that ones in the production streams. Other important issue associated to the well test is the employment of new technologies, that helps to reduce the uncertainty of measurement as digital communication between the field devices and the flow computer through an open protocol as the Foundation Field bus. Another indication of technology evolution in the flow measurement focusing a lower uncertainty is the new version of API MPMS 11.1:2004, that requires calculation with double precision floating point, as well the correction factors with 5 decimal digits. (author)

  1. Theoretical study of excitonic complexes in semiconductors quantum wells; Estudo teorico de complexos excitonicos em pocos quanticos de semicondutores

    Energy Technology Data Exchange (ETDEWEB)

    Dacal, Luis Carlos Ogando

    2001-08-01

    A physical system where indistinguishable particles interact with each other creates the possibility of studying correlation and exchange effect. The simplest system is that one with only two indistinguishable particles. In condensed matter physics, these complexes are represented by charged excitons, donors and acceptors. In quantum wells, the valence band is not parabolic, therefore, the negatively charged excitons and donors are theoretically described in a simpler way. Despite the fact that the stability of charged excitons (trions) is known since the late 50s, the first experimental observation occurred only at the early 90s in quantum well samples, where their binding energies are one order of magnitude larger due to the one dimensional carriers confinement. After this, these complexes became the subject of an intense research because the intrinsic screening of electrical interactions in semiconductor materials allows that magnetic fields that are usual in laboratories have strong effects on the trion binding energy. Another rich possibility is the study of trions as an intermediate state between the neutral exciton and the Fermi edge singularity when the excess of doping carriers is increased. In this thesis, we present a theoretical study of charged excitons and negatively charged donors in GaAs/Al{sub 0.3}Ga{sub 0.7}As quantum wells considering the effects of external electric and magnetic fields. We use a simple, accurate and physically clear method to describe these systems in contrast with the few and complex treatments s available in the literature. Our results show that the QW interface defects have an important role in the trion dynamics. This is in agreement with some experimental works, but it disagrees with other ones. (author)

  2. Acid rock drainage in the uranium mining and milling site of Pocos de Caldas, Brazil -- duration assessment, pollutant generation modelling and remediation strategies

    International Nuclear Information System (INIS)

    Fernandes, H.M.; Franklin, M.R.

    2002-01-01

    This geochemical modeling work was carried out to simulate the acid drainage generation from one of the waste-rock piles at the Pocos de Caldas uranium mining site. The mathematical code STEADQYL was used. The estimated results were in good agreement for sulphate and uranium concentrations and the duration of the acid water generation was estimated to be about 500 years. The effect of covering the dump with a material that minimized oxygen diffusion was assessed. Projections indicated that covering the dump with a 1.0 m thickness of a material (like clay), which had an oxygen diffusion coefficient of 10 9 m 2 ·s 1 , would reduce the pollutant concentrations to acceptable values. The estimated cost, when using this strategy, would be about US $10 million. (author)

  3. Hydrogeochemical applications of natural isotope of the U (4n+2) and Th(4n) series in Morro do Ferro, Pocos de Caldas (MG), Brazil

    International Nuclear Information System (INIS)

    Bonotto, D.M.

    1987-01-01

    Uranium and thorium isotopic analysis were performed on well spoils of the ore body at Morro do Ferro, Pocos de Caldas (MG), Brazil, using groundwater from several boreholes in the area and surface water from a stream and that originates at the base of the hill. For uranium and thorium extraction, a chemical process was applied to samples; activites of 228 Th and 232 Th radioisotopes (4n+2 series) were determined by alpha spectrometry. The uranium concentration and 234 U/ 238 U isotope ratio in groundwater were applied to developed models for deducing proportions of water in a mixture and for characterizing uranium accumulation. The correlation between variability in concentration of uranium dissolved in groundwater and alteration of the level of the water table due to infiltration of rainfall was observed. Chemical analysis of the major and minor compounds for groundwater of the ore body zone were done. (Author) [pt

  4. Hydrogeochemical utilization of natural isotopes from U(4n+2) and Th(4n) series at Morro do Ferro, Pocos de Caldas (MG)

    International Nuclear Information System (INIS)

    Bonotto, D.M.

    1991-01-01

    Uranium and thorium isotopic analysis were performed on well spoils of the main ore body at Morro do Ferro, Pocos de Caldas (MG), using groundwater from several boreholes in the area and surface water from a steam that originates at the base of the hill. For extraction of uranium and thorium a long chemical process was applied to samples; activities of 228Th and 232 Th isotopes (4n series) and also of 238U, 234U and 230Th isotopes (4n+2 series)were determined by the alpha spectrometry method. The ratios 234U?238U determined for well spoils did not show marked disequilibria between these isotopes. However, the ratios 228Th/232Th and 230Th/234U obtained in some samples showed a high disequilibrium between these isotopes, associated with the presence of possible zones of removal of uranium and precipitation of radium.(author)

  5. Una causa poco frecuente de hipertrabeculación exclusiva del ventrículo derecho: ventrículo derecho no compacto

    Directory of Open Access Journals (Sweden)

    Juan C. Díaz, MD

    2013-07-01

    Full Text Available La cardiopatía por falta de compactación ventricular es una entidad infrecuente, que generalmente compromete el ventrículo izquierdo ocasionando falla cardíaca, arritmias ventriculares, embolismo periférico y muerte súbita. Hasta el momento, se han descrito muy pocos casos de ventrículo derecho no compacto, por lo cual no hay criterios diagnósticos establecidos y se desconoce como es la evolución clínica y la respuesta al tratamiento de este grupo de pacientes. Se describe el caso de un paciente con hipertrabeculación marcada del ventrículo derecho en quien se descartó un origen estructural de la misma, haciéndose diagnóstico de ventrículo derecho no compacto.

  6. Una causa poco frecuente de hipertrabeculación exclusiva del ventrículo derecho: ventrículo derecho no compacto

    Directory of Open Access Journals (Sweden)

    Juan C Díaz

    2013-08-01

    Full Text Available La cardiopatía por falta de compactación ventricular es una entidad infrecuente, que generalmente compromete el ventrículo izquierdo ocasionando falla cardíaca, arritmias ventriculares, embolismo periférico y muerte súbita. Hasta el momento, se han descrito muy pocos casos de ventrículo derecho no compacto, por lo cual no hay criterios diagnósticos establecidos y se desconoce como es la evolución clínica y la respuesta al tratamiento de este grupo de pacientes. Se describe el caso de un paciente con hipertrabeculación marcada del ventrículo derecho en quien se descartó un origen estructural de la misma, haciéndose diagnóstico de ventrículo derecho no compacto.

  7. Petrography, structure and geochemistry of nepheline syenites from the Pocos de Caldas alkaline massif, states of Minas Gerais and Sao Paulo, Brazil

    International Nuclear Information System (INIS)

    Ulbrich, H.H.

    1984-01-01

    The subcircular Mid-Cretaceous Pocos de Caldas alkaline massif, states of Minas Gerais and Sao Paulo, southern Brazil, covers over 800 Km 2 , and has as its main rock types phonolites and nepheline syenites, with subordinate amounts of pyroclastic rocks. Nepheline syenites consist mainly of K-feldspar, nepheline and pyroxene, varying both in texture and 'rare-metal silicates' content. A useful petrographic division is that which classifies the rocks into agpaitic and non-agpaitic (miaskitic or intermediate) types. The latter varieties, characterized by the absence of rare-metal silicates, are predominant by far; agpaitic types are easily recognized by the presence of eudialyte and other rare-metal silicates. Both petrographic and, as far as possible, structural descriptions as well are given for most of the mapped nepheline syenite bodies; many bodies show subhorizontal or moderately-dipping contacts with their country rocks. Chemically, these rocks show, on the whole, high alkaline contents (12-15%) and commonly very high K 2 O abundances. Chemical as well as additional isotopic and geochronological (Rb/Sr) data suggest that the asthenosphere is the source of parental magmas for the Pocos de Caldas nepheline syenites. The same arguments are used to reject, as unlikely, the magmatic activity interval (over 30 m.y.) given by previously published K/Ar ages. Simple structural models of the crust lithosphre in the Parana Basin area, coupled with the westward plate movement, suggest that irregularities at the asthenosphere-lithosphere decoupling surface are probable sites for melting of asthenospheric (and lithospheric) rocks induced by pressure relief. (D.J.M.) [pt

  8. Radium-226 and head-210 in agriculture products produced on the environs of the uranium mine and mill at the Pocos de Caldas plateau in Minas Gerais

    International Nuclear Information System (INIS)

    Vasconcellos, L.M.H.; Amaral, E.C.S.; Vianna, M.E.C.M.; Franca, E.P.

    1986-01-01

    Radium-226 and Lead-210 in agriculture products produced on the environs of the uranium mine and mill at the Pocos de Caldas Plateau in Minas Gerais. As a complement to the pre-operational environmental monitoring program of the Brazilian first uranium mine and mill, a survey of 226 Ra and 210 Pb in agriculture products, and in the corresponding soils, were carried out in the Pocos de Caldas Plateu. The survey intended to determine site specific transfer factors, in order to better estimate radiation doses on the population, resulting from the plant operation. In local soils, 226 Ra and 210 Pb have similar concentrations. The average contents are comparable to the values found in areas of normal radioactivity, but the maximum values are higher by one order of magnitude. In the vegetables analyzed (beans, carrot, corn and potato), 226 Ra concentrations are slightly higher than those of 210 Pb, and the maximum values are also one order of magnitude greater than in normal regions. For both radionuclides, the average soil-to-plant transfer factors are of the order of 10 -3 and 10 -2 when related to total and to exchangeable content soil, respectively. These results led to the conclusion that 226 Ra and 210 Pb have similar importance, concerning the population exposure via the foodstuff ingestion pathway. Therefore, it was recommended to carry on routine monitoring program for both radionuclides in the main agriculture crops. However, the naturally elevated radionuclide concentrations, in some local vegetables, will decrease the sensivity for detecting for detecting small increments resulting from the plant operation. (Author) [pt

  9. Complicaciones posoperatorias y mortalidad en pacientes operados por endocarditis infecciosa Postoperative complications and mortality observed in patients operated on from infective endocarditis

    Directory of Open Access Journals (Sweden)

    Joaquín Gómez Armando Gonga

    2013-03-01

    Full Text Available Objetivo: describir las causas de morbilidad y mortalidad perioperatorias en los pacientes afectos de endocarditis infecciosa activa y significar cómo pueden ser disminuidas. Métodos: se realizó un estudio retrospectivo de las complicaciones posoperatorias y mortalidad en 139 pacientes operados por presentar endocarditis infecciosa en un período de 16 años. Se efectuaron 147 operaciones a los 139 pacientes de las cuales 83 (57,1 % fueron electivas y 64 (42,9 % fueron de urgencia. El 24 % de los pacientes fueron remitidos de otros centros en los que habían sido sometidos a tratamiento médico no exitoso por más de 4 semanas. Resultados: las operaciones efectuadas fueron: Sustituciones valvulares aórticas,mitrales y tricuspídeas 75 (41,1 %, extracción de electrodos de marcapasos o desfibriladores automáticos implantables del ventrículo derecho 57 (41 % , otras operaciones en número de 7 (4,9 %y 8 reintervenciones. La complicación más frecuente fue la sepsis generalizada (10,07 % pObjective: To describe the causes of perioperative morbidity and mortality of patients suffering active infectious endocarditis and to explain how both aspects can be reduced. Methods: A retrospective study of postoperative complications and mortality observed in 139 patients operated on from infectious endocarditis in 16 years. One hundred forty seven surgeries were performed, of which 83 (57.1 % were elective and 64 (42.9 % were emergency surgeries. In this group, 24 % had been referred from other medical centers where they had been unsuccessfully treated for 4 weeks. Results: The performed surgeries comprised 15 aortic, mitral and tricuspid valve replacements, 57 (41 % removals of pacemaker electrodes or of implanted automatic defibrillators in the right ventricle, seven other types of surgeries and 8 reoperations. The most frequent complication was generalized sepsis ((10.07 % p< 0.01, followed by the low heart output and postoperative bleeding. The

  10. Factores asociados a complicaciones de la colangiopancreatografía retrógrada endoscópica en un hospital de alta complejidad Factors associated to complications of endoscopic retrograde cholangiopancreatography in a third-level hospital

    Directory of Open Access Journals (Sweden)

    Angel Quispe-Mauricio

    2010-06-01

    Full Text Available El tratamiento endoscópico de las enfermedades de la vía biliar es posible gracias a la colangiopancreatografía retrógrada endoscópica (CPRE; no obstante, no está exenta de complicaciones. Objetivos. Describir las características e indicaciones de la CPRE y determinar los factores asociados al desarrollo de complicaciones tras la realización de este procedimiento. Materiales y métodos. Se realizó un estudio observacional retrospectivo en el Departamento de Gastroenterología del Hospital Nacional Guillermo Almenara Irigoyen en Lima, Perú; desde marzo de 2002 a junio de 2005. Resultados. Se evaluaron 294 informes en 280 pacientes, la mediana de la edad fue 58 y 155 (52,7% fueron mujeres; cinco procedimientos se efectuaron en la Unidad de Cuidados Intensivos (UCI. La indicación más frecuente fue la coledocolitiasis en el 67,3% de los casos, 205 (69,7% procedimientos fueron exitosos complicándose sólo 33 de ellos. Las complicaciones más frecuentes fueron la pancreatitis aguda y la hemorragia, en 16 y 13 pacientes, respectivamente. No se reportó casos de perforación o defunción. La canulación del conducto pancreático más de una vez fue un factor asociado (OR=2,01; IC95%: 1,11 - 5,92; p=0,03. Conclusiones. El 11,2% de los casos se complicaron, siendo la pancreatitis aguda y la hemorragia leve las complicaciones más frecuentes. Sólo la canulación al conducto pancreático en más de una oportunidad es un factor asociado para tener complicaciones.Endoscopic treatment of the bile duct diseases is possible thanks to the ERCP (endoscopic retrograde cholangio pancreatography, nevertheless, it is not free of complications. Objectives. To describe the characteristics and indications of the ERCP and determine the factors associated to the development of complications after performing the procedure. Materials and methods. An observational retrospective study was done in the Gastroenterology Department of the Hospital Guillermo Almenara

  11. The experience of Electricity Municipal Department of Pocos de Caldas, state of Minas Gerais, Brazil, in conception and construction of Antas 2 hydroelectric power plant: a hand-made power plant; A experiencia do Departamento Municipal de Eletricidade de Pocos de Caldas na concepcao e construcao da Usina Hidreletrica Antas 2: uma usina concebida e realizada na ponta do lapis

    Energy Technology Data Exchange (ETDEWEB)

    Moraes, Cicero Machado de [Departamento Municipal de Eletricidade de Pocos de Caldas, MG (Brazil); Nasseh, Oscar [Mecanica Pesada S.A., Taubate, SP (Brazil); Hellmuth, Harald [Siemens S.A. (Brazil)

    1993-12-31

    The Antas 2 hydroelectric power plant, located in Pocos de Caldas, state of Minas Gerais, Brazil, is under construction and have deadline to start operation in the beginning of 1994. Considered a high-head plant, with 165,05 m of fall, Antas 2 have three generation units of 5,7 MW and will supply a residential and industry demand of electric energy. This paper presents that the construction of an energy profit with this capacity can be performed under the mostly updated technologies with low costs, resulting in a high productivity, with reliance and asserted rentability profit 1 tab.

  12. Tratamiento quirúrgico de las complicaciones del shock meningocóccico grave Surgical treatment of the severe meningococcal septic shock complications

    Directory of Open Access Journals (Sweden)

    P. Casteleiro Roca

    2010-06-01

    Full Text Available El shock meningocóccico es una entidad relativamente frecuente y de pronóstico muy grave, que provoca fallo multiorgánico con una alta mortalidad y que precisa ingreso en Unidad de Cuidados Intensivos. En los casos grandes puede provocar necrosis de tejidos mediante una fisiopatología poco clara. En los últimos años la supervivencia de estos pacientes ha aumentado debido al diagnóstico precoz y a medidas de reanimación más agresivas. Como consecuencia encontramos un aumento del número de pacientes con necrosis extensas de tejidos que precisan tratamiento. Lo fundamental ante el diagnóstico de un shock meningocóccico es establecer el tratamiento médico precoz con medidas de reanimación agresivas y antibioterapia. Sugerimos que la necrosis extensa de tejidos que sufren estos pacientes debe tratarse como si se tratase de un paciente quemado, realizando curas diarias con sulfadiacina argéntica y cirugías seriadas (desbridamiento - amputación - cobertura tan pronto como la situación clínica del paciente lo permita. Es necesario un seguimiento muy cercano de estos pacientes, dada la necesidad de cirugías secundarias que van a precisar a lo largo de su vida, así como la realización de pruebas de imagen para descartar la presencia de osteomielitis secundarias.Meningococcal shock is a relatively frequent disease with a serious prognosis, that causes a multiorganic failure with high mortality and Intensive Care Unit admission. Serious meningococcal shock causes tissue necrosis by uncertain physiopathology. In the last years, there is an increase of the survival, as a result of early diagnosis and aggressive resuscitation. So, there is an increase of patient's tissue necrosis that needs surgery. The most important aspect in front of meningococcal shock is to establish early medical treatment with aggressive resuscitation and antibiotics. Tissue necrosis should be treated like burn patient: argentic sulfadiazine daily cure and serial

  13. Complicaciones postquirúrgicas en la población infantil de 1 a 17 años intervenidos por trauma abdominal y torácico en el servicio de cirugía pediátrica del hospital “Carlos Andrade Marín” desde el mes de junio de 2013 hasta septiembre de 2016

    OpenAIRE

    López Vaca, César Augusto

    2017-01-01

    El trauma pediátrico provoca altos índices de mortalidad y morbilidad, que generan gran coste económico y humano, por lo que requiere de métodos que permitan hacer una estimación del riesgo de aparición de complicaciones y de esta manera identificarlas y tratarlas tempranamente. Objetivo: Identificar los factores asociados a complicaciones postquirúrgicas en la población infantil de 1 a 17 años intervenidos por trauma abdominal y torácico en el servicio de Cirugía Pediátrica del Hospital “Ca...

  14. Concentrations of 226Ra and 210Pb in agricultural products surrounding the first brazilian mine and mill in Pocos de Caldas, MG

    International Nuclear Information System (INIS)

    Vasconcellos, L.M.H.; Amaral, E.C.S.; Vianna, E.C.M.

    1989-01-01

    As a complement to the pre-operational environmental monitoring program of the Brazilian first uranium mine and mill, a survey of 226 Ra and 210 Pb in agriculture products, and in the corresponding soils, were carried out in the Pocos de Caldas Plateau. The survey intended to determine site specific transfer factors, in order to better estimate radiation doses on the population. Resulting from the plant operation. In local soils, 226 Ra and 210 Pb have similar concentrations. The average contents are comparable to the values found in areas of normal radioactivity, but the maximum values are higher by one order of magnitude. In the vegetables analyzed (beans, carrot, corn and potato), 226 Ra concentrations are slightly higher than those of 210 Pb, and the maximum values are also one order of magnitude greater than in normal regions. For both radionuclides, the average soil-to-plant transfer factors are of the order of 10 -3 and 10 -2 , when related to total and to exchangeable contents in soils, respectively. These results led to the conclusion that 226 Ra and 210 Pb have similar importance, concerning the population exposure via the foodstuff ingestion pathway. Therefore, it was recommended to carry on routine monitoring program for both radionuclides in the main agriculture crops. However, the naturally elevated radionuclide concentrations, in some local vegetables, will decrease the sensitivity for detecting small increments resulting from the plant operation. (author) [pt

  15. Study of radon and thoron gas behaviour in the air at the commercial centers in Rio de Janeiro and Pocos de Caldas city

    International Nuclear Information System (INIS)

    Castro, Carlos A.C.; Cardoso, Domingos D.

    2005-01-01

    The radon is a radioactive gas. It occurs naturally in the atmosphere coming from the decay of radium, with emission of alpha particles. There are three radon isotopes more known, of which the most important under the environmental point of view is the Rn-222, whose half life is 3.82 days. The radon and their descendants are responsible by more than 40 % of the natural radioactive dose received for the human beings inside the building. In doses above 4 pCi/l, given as occupational dose, can cause among other diseases, the lung cancer. The main source of radon inside the building is the soil. The incidence of radon inside the building varies according to the soil composition, the materials employed in its construction, the inside air temperature and humidity, time during the day, season and the ventilation process designed. The work was realized at the commercial centers in Rio de Janeiro and Pocos de Caldas, for methodology confirmation. It was utilized the passive (track detectors) and active (two filters technique. Kusnetz technique, Tsivoglou technique and alpha spectrometry technique) methods. The objective of this work was to analyze the radon and thoron concentrations levels in order to supply parameters upon the quality of the air in those commercial centers. (author)

  16. Geomorphological and hydrogeological features of the Pocos de Caldas caldera and the Osamu Utsumi mine and Morro do Ferro analogue study sites, Brazil

    International Nuclear Information System (INIS)

    Holmes, D.S.; Noy, D.J.; Pitty, A.E.

    1990-01-01

    The Osamu Utsumi mine and Morro do Ferro study sites lie within the Pocos de Caldas plateau which is roughly circular in outline with a diameter of 35 km and an area of approximately 800 km 2 . Its general altitude lies between 1300 and 1600 m. The plateau is the eroded form of a caldera which initially intruded some 80 million years ago. Geomorphologically, both sites occupy watershed areas adjacent to small streams in the centre of the plateau. The climate of the area has a marked wet season from November to April and is dry the rest of the year. The streams are ephemeral in their upper reaches, tending to dry up in the dry season as they are fed by a declining base flow. In the wet season they exhibit flash floods fed by high-intensity rainfall causing overland flow. The wet season also provides recharge to the groundwater. Natural slopes are steep and the original vegetaion was thin forest cover which is now restricted to the valley bottoms; usable slopes have poor quality grass cover used for cattle grazing. The plateau is a stable feature and its surface has been eroding at an average rate of 12 m per million years over a period of 50 million years. (author) 21 figs., 47 refs

  17. Accumulation of sup 210 Po in foodstuffs cultivated in farms around the Brazilian mining and milling facilities on Pocos de Caldas plateau

    Energy Technology Data Exchange (ETDEWEB)

    Santos, P L; Gouvea, R C; Dutra, I R [Universidade Federal, Rio de Janeiro, RJ (Brazil). Inst. de Biologia; Gouvea, V A [Brazilian Energy Commission, Rio de Janeiro (Brazil). Int. of Radioprotection and Dosimetry

    1990-01-01

    Several sample types from the environment of the uranium mining and milling facilities of Pocos de Caldas plateau (CIPC) in Minas Gerais state, Brazil have been assayed for their concentrations of uranium and its daughters. This paper presents the data for {sup 210}Po in food, soils and fertilizers in the CIPC region and, for comparison, the corresponding results from a vegetable garden in a control region in Joinville, in the state of Santa Catarina. The results show that vegetables from two gardens near the CIPC region have no significance differences in Po content, despite the closeness of one of the sites to a uranium mine. For some species of vegetables, however, nearsite values were twice those in the control region. Superphosphate fertilizers influence the accumulation of {sup 210}Po by plants, as well as the concentrations in soils, and their contribution is more evident than the local deposition. The major concentration in the leaf and stem suggests that the accumulation of {sup 210}Po in vegetables is due chiefly to its deposition on and absorption by their leaves. (author).

  18. Near-field high-temperature transport: Evidence from the genesis of the Osamu Utsumi uranium mine, Pocos de Caldas alkaline complex, Brazil

    International Nuclear Information System (INIS)

    Cathles, L.M.; Shea, M.E.

    1990-01-01

    The chemical, isotopic and mineralogical alteration which occurred during primary uranium ore deposition at the breccia pipe-hosted Osamu Utsumi mine, Pocos de Caldas, Brazil, was studied as a natural analogue for near-field radionuclide migration. Chemical and isotopic alteration models were combined with finite difference models of the convective cooling of caldera intrusives. Application of the chemical models successfully used to interpret mineralization and alteration at the Osamu Utsumi mine to the hypothetical waste repository shows that even in a worst case scenario (waste emplaced in a permeable host rock with no measures taken to inhibit flow through the repository), the amount of hydrothermal alteration in the hypothetical repository will be about 0.1% of that in the breccia pipe at the Osamu Utsumi mine. Assuming no barriers to uranium mobility, uranium precipitation above the hypothetical repository would be 0.05 ppm (rather than 50 ppm), hydrothermal alteration 0.03 wt.% (rather than 30 wt.%), etc. The analysis indicates that mineralogical alteration is extremely sensitive to thermodynamic data. Prediction of mineralogical alteration (which may be necessary to predict the migration of radionuclides other than uranium, for example) probably cannot be based directly on even very carefully collected laboratory thermodynamic data. Mineralogical complexities of the system, as well as database uncertainties, will require calibration of the thermodynamic framework against mineralogical alteration observed in the laboratory or field by procedures briefly described. (au)

  19. Usual coffee intake in Brazil: results from the National Dietary Survey 2008-9.

    Science.gov (United States)

    Sousa, Alessandra Gaspar; da Costa, Teresa Helena Macedo

    2015-05-28

    Coffee is central to the economy of many developing countries, as well as to the world economy. However, despite the widespread consumption of coffee, there are very few available data showing the usual intake of this beverage. Surveying usual coffee intake is a way of monitoring one aspect of a population's usual dietary intake. Thus, the present study aimed to characterise the usual daily coffee intake in the Brazilian population. We used data from the National Dietary Survey collected in 2008-9 from a probabilistic sample of 34,003 Brazilians aged 10 years and older. The National Cancer Institute method was applied to obtain the usual intake based on two nonconsecutive food diaries, and descriptive statistical analyses were performed by age and sex for Brazil and its regions. The estimated average usual daily coffee intake of the Brazilian population was 163 (SE 2.8) ml. The comparison by sex showed that males had a 12% greater usual coffee intake than females. In addition, the highest intake was recorded among older males. Among the five regions surveyed, the North-East had the highest usual coffee intake (175 ml). The most common method of brewing coffee was filtered/instant coffee (71%), and the main method of sweetening beverages was with sugar (87%). In Brazil, the mean usual coffee intake corresponds to 163 ml, or 1.5 cups/d. Differences in usual coffee intake according to sex and age differed among the five Brazilian regions.

  20. Geochemical modelling of water-rock interactions at the Osamu Utsumi mine and Morro do Ferro analogue study sites, Pocos de Caldas, Brazil

    International Nuclear Information System (INIS)

    Nordstrom, D.K.; Puigdomenech, I.; McNutt, R.H.

    1990-01-01

    Geochemical processes involving water-rock interactions have been modelled using groundwater composition, mineralogical data, ion plots and computations of speciation, non-thermodynamic mass balance and thermodynamic mass transfer for two natural analogue sites near Pocos de Caldas, Brazil: the Osamu Utsumi mine and Morro do Ferro. The main rock type is an alkaline igneous complex composed of volcanic and sub-volcanic phonolites that have been hydrothermally altered and highly weathered. This altered rock mass grades from a laterite at the surface to a saprolite and finally to unweathered, hydrothermally altered bedrock at depth. The mine site contains high concentrations of uranium and Morro do Ferro contains high concentrations of thorium and rare-earths. The reaction models can reproduce the water chemistry and mineral occurences and they were validated by predicting the masses of minerals precipitated and the pH of the final water. The model computations can also reproduce the pH and iron concentrations of the water samples during CO 2 degassing and iron(II) oxidation from exposure to air. The results from the geochemical reaction models reveal that the dominant processes are production of CO 2 in the soil zone through aerobic decay of organic matter, dissolution of fluorite, calcite, K-feldspar, albite and manganese oxides, oxidation of pyrite and sphalerite and precipitation of ferric oxides, silica and kaolinite. Recharge waters are undersaturated with respect to barite and discharging waters and deeper groundwaters are saturated to supersaturated with respect to barite, demonstrating a strong equilibrium solubility control. Strontium isotope data demonstrate that sources other than calcium-bearing minerals are required to account for the dissolved strontium in the ground. These may include K-feldspar, smectite-chlorite mixed-layer clays and goyazite. (author) 24 figs., 4 tabs., 18 refs

  1. Geomorphological and hydrogeological features of the Pocos de Caldas caldera and the Osamu Utsumi mine and Morro do Ferro analogue study sites, Brazil

    International Nuclear Information System (INIS)

    Holmes, D.C.; Pitty, A.E.; Noy, D.J.

    1990-01-01

    The Osamu Utsumi mine and Morro do Ferro study sites lie within the Pocos de Caldas plateau which is roughly circular in outline with a diameter of 35 km and an area of approximately 800 km 2 . Its general altitude lies between 1300 and 1600 m. The plateau is the eroded form of a caldera which was initially intruded some 80 million years ago. Geomorphologically, both sites occupy watershed areas adjacent to small streams in the centre of the plateau. The climate of the area has a market wet season from November to April and is dry the rest of the year. The streams are ephemeral in their upper reaches, tending to dry up in the dry season as they are fed by a declining base flow. In the wet season they exhibit flash flood fed by high-intensity rainfall causing overland flow. The wet season also provides recharge to the groundwater. Natural slopes are steep and the original vegetation was thin forest cover which is now restricted to the valley bottoms; usable slopes have poor quality grass cover used for cattle grazing. The plateau is a stable feature and its surface has been eroding at an average rate of 12 m per million years over a period of 50 million years. The mine geology is dominantly volcanic to subvolcanic phonolites that have been hydrothermally altered. Fracturing of the rock is extensive. Downward diffusion of oxygen in groundwaters during deep weathering has produced a distinct redox zone seen as a colour change from green/grey to brown/yellow. Morro do Ferro has a more weathered version (laterite/clay) of the same geology penetrated by magnetite breccia dykes. Whilst the area surrounding Morro do Ferro remains untouched, that around the mine has been seriously disturbed by mining activity which has penetrated the water-table. The existing mine has modified groundwater flow patterns and disturbed the movement of oxidising and reducing waters. (au) (47 refs.)

  2. Compared With Usual Sodium Intake, Low- and Excessive-Sodium Diets Are Associated With Increased Mortality

    DEFF Research Database (Denmark)

    Graudal, Niels; Jürgens, Gesche; Baslund, Bo

    2014-01-01

    BACKGROUND: The effect of sodium intake on population health remains controversial. The objective was to investigate the incidence of all-cause mortality (ACM) and cardiovascular disease events (CVDEs) in populations exposed to dietary intakes of low sodium (<115 mmol), usual sodium (low usual so...

  3. 22 CFR 92.85 - Service of legal process usually prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Service of legal process usually prohibited. 92... RELATED SERVICES Quasi-Legal Services § 92.85 Service of legal process usually prohibited. The service of process and legal papers is not normally a Foreign Service function. Except when directed by the...

  4. Marlboro and Other Usual Brand Choices by Youth Smokers in Middle Eastern Countries

    Science.gov (United States)

    Page, Randy M.

    2012-01-01

    This study analyzed data from 118,743 adolescents completing 30 different Global Youth Tobacco Surveys conducted in 15 different Middle Eastern countries between 1999 and 2007 to determine the proportion of young smokers who usually smoked Marlboro, other cigarette brands, or no usual brand smoked in these countries. Marlboro was the most…

  5. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study

    NARCIS (Netherlands)

    Gottlieb, D.J.; Hek, K.; Chen, T.H.; Watson, N.F.; Eiriksdottir, G.; Byrne, E.M.; Cornelis, M.; Warby, S.C.; Bandinelli, S.; Cherkas, L.; Evans, D.S.; Grabe, H.J.; Lahti, J.; Li, M.; Lehtimäki, T.; Lumley, T.; Marciante, K.; Pérusse, L.; Psaty, B.M.; Robbins, J.; Tranah, G.; Vink, J.M.; Wilk, J.B.; Stafford, J.M.; Bellis, M.; Biffar, R.; Bouchard, C.; Cade, B.; Curhan, G.C.; Eriksson, J.G.; Ewert, R.; Ferrucci, L.; Fülöp, T.; Gehrman, P.R.; Goodloe, R.; Harris, T.B.; Heath, A.C.; Hernandez, D.; Hofman, A.; Hottenga, J.J.; Hunter, D.J.; Jensen, M.K.; Johnson, A.D.; Kähönen, M.; Kao, L.; Kraft, P.; Larkin, E.K.; Lauderdale, D.S.; Luik, A.I.; Medici, M.; Montgomery, G.W.; Palotie, A.; Patel, S.R.; Pistis, G.; Porcu, E.; Quaye, L.; Raitakari, O.; Redline, S.; Rimm, E.B.; Rotter, J.I.; Smith, A.V.; Spector, T.D.; Teumer, A.; Uitterlinden, A.G.; Vohl, M.-C.; Widén, E.; Willemsen, G.; Young, T.; Zhang, X.; Liu, Y.; Blanger, J.; Boomsma, D.I.; Gudnason, V.; Hu, F.; Mangino, M.; Martin, N.G.; O'Connor, G.T.; Stone, K.L.; Tanaka, T.; Viikari, J.; Gharib, S.A.; Punjabi, N.M.; Räikkönen, K.; Völzke, H.; Mignot, E.; Tiemeier, H.

    2015-01-01

    Usual sleep duration is a heritable trait correlated with psychiatric morbidity, cardiometabolic disease and mortality, although little is known about the genetic variants influencing this trait. A genome-wide association study (GWAS) of usual sleep duration was conducted using 18 population-based

  6. Novel loci associated with usual sleep duration: The CHARGE Consortium Genome-Wide Association Study

    NARCIS (Netherlands)

    D.J. Gottlieb (Daniel J); K. Hek (Karin); T.-H. Chen; N.F. Watson; G. Eiriksdottir (Gudny); E.M. Byrne; M. Cornelis (Marilyn); S.C. Warby; S. Bandinelli; L. Cherkas (Lynn); D.S. Evans (Daniel); H.J. Grabe (Hans Jörgen); J. Lahti (Jari); M. Li (Man); T. Lehtimäki (Terho); T. Lumley (Thomas); K. Marciante (Kristin); L. Perusse (Louis); B.M. Psaty (Bruce); J. Robbins; G.J. Tranah (Gregory); J.M. Vink; J.B. Wilk; J.M. Stafford; C. Bellis (Claire); R. Biffar; C. Bouchard (Claude); B. Cade; G.C. Curhan (Gary); J. Eriksson; R. Ewert; L. Ferrucci (Luigi); T. Fülöp; P.R. Gehrman (Philip); R. Goodloe (Robert); T.B. Harris (Tamara); A.C. Heath (Andrew C.); D.G. Hernandez (Dena); A. Hofman (Albert); J.J. Hottenga (Jouke Jan); D. Hunter (David); M.K. Jensen (Majken K.); A.D. Johnson (Andrew); M. Kähönen (Mika); W.H.L. Kao (Wen); P. Kraft (Peter); E.K. Larkin; D.S. Lauderdale; A.I. Luik (Annemarie I); M. Medici; G.W. Montgomery (Grant W.); A. Palotie; S.R. Patel (Sanjay); G. Pistis (Giorgio); E. Porcu; L. Quaye (Lydia); O. Raitakari (Olli); S. Redline (Susan); E.B. Rimm (Eric B.); J.I. Rotter; A.V. Smith; T.D. Spector (Timothy); A. Teumer (Alexander); A.G. Uitterlinden (André); M.-C. Vohl (Marie-Claude); E. Widen; G.A.H.M. Willemsen (Gonneke); T.L. Young (Terri L.); X. Zhang; Y. Liu; J. Blangero (John); D.I. Boomsma (Dorret); V. Gudnason (Vilmundur); F. Hu; M. Mangino; N.G. Martin (Nicholas); G.T. O'Connor (George); K.L. Stone (Katie L); T. Tanaka; J. Viikari (Jorma); S.A. Gharib (Sina); N.M. Punjabi (Naresh); K. Räikkönen (Katri); H. Völzke (Henry); E. Mignot; H.W. Tiemeier (Henning)

    2015-01-01

    textabstractUsual sleep duration is a heritable trait correlated with psychiatric morbidity, cardiometabolic disease and mortality, although little is known about the genetic variants influencing this trait. A genome-wide association study (GWAS) of usual sleep duration was conducted using 18

  7. Characterization of the geochemical processes present in the radionuclides and metals mobilization in the tailing dam at the Uranium Mining and Milling Facilities - Pocos de Caldas, MG, Brazil

    International Nuclear Information System (INIS)

    Pinto, Patricia Freitas

    1995-08-01

    In Brazil, the first step of nuclear fuel cycle - the mining and milling of the uranium ore - is developed at the Uranium Mining and Milling Facilities of Pocos de Caldas, Minas Gerais state. The wastes management is a very important aspect of the process. The understanding of the geochemical processes that occur in the tailings dam is a key question to define a plan of action concerning the decommissioning strategy of the facility. The objective of the present work was to give some issues to help in the adoption of the remedial actions concerning the decommissioning of the facility. It focused on the characterization of the most important geochemical processes regulating the mobilization of radionuclides and heavy metals in the tailings dam. Two cores from the tailings dam (uncovered area) were collected. Seepage and drainage waters were sampled, the same being true for the tailings dam lake. Groundwater form an aquifer bellow the tailings dam and superficial waters from a river that receives the effluents of the dam (Soberbo River) were also sampled. Data from the mining company were used to calculate the inventory of radionuclides and heavy metals deposited in the waste dam.The obtained results showed that pyrite oxidation is the key process in the mobilization of radionuclides and heavy metals from the wastes. Pyrite oxidation is a process regulated by oxygen diffusion and water. In the studied scenario it could be shown that the process was limited to a one meter deep layer in the uncovered part of the waste dam. Because of this, Fe, Al, Mn, Zn, Th and 238 U showed higher concentrations in the bottom layers of the cores in relation to the upper ones. 226 Ra and 210 Pb showed opposite patterns. The coprecipitation with Ca SO 4 was the most relevant mechanism in both radionuclides immobilization in the wastes. Sulfate was the only chemical species that could be assigned as a contaminant in aquifer bellow the waste dam. As a conclusion, the target environmental

  8. Distribución y caracterización morfológica de Hycleus duodecimmaculatus (Olivier, 1811 (Coleoptera, Meloidae, una especie poco conocida del oeste de Marruecos

    Directory of Open Access Journals (Sweden)

    Ruiz, José L.

    2014-06-01

    Full Text Available Hycleus duodecimmaculatus (Coleoptera, Meloidae, Mylabrini is a poorly known species endemic to Morocco. Its geographic range extends along the coastal-subcoastal fringe of the Atlantic Coast, between Larache and Tiznit region (Arbaa Ait Ahmed. In this paper we study more than a hundred specimens, mostly preserved in the collection of the Museo Nacional de Ciencias Naturales (MNCN-CSIC, Spain. We provide new geographic records, including the Western Rif and confirm its presence in Marrakech (northwestern slopes of the High Atlas. Because of the scarcity of information, disperse and sometimes erroneous, we synthesize information available on chorology and phenology, and characterize the typology of the species’ habitat. From a taxonomic point of view, we redefine the species’ diagnostic characters and illustrate various aspects of the intra- and interpopulational morphological variability.Hycleus duodecimmaculatus (Coleoptera, Meloidae, Mylabrini es un endemismo de Marruecos muy poco conocido, cuya distribución se extiende por la franja costera-subcostera del Marruecos atlántico, entre Larache y la región de Tiznit (Arbaa Ait Ahmed. En este trabajo, realizado principalmente a partir del estudio de más de un centenar de ejemplares conservados en su mayor parte en la colección del Museo Nacional de Ciencias Naturales (MNCN-CSIC, España, se aportan nuevas citas geográficas incluyendo el Rif occidental, y se confirma su presencia en Marrakech (falda noroccidental del Alto Atlas. A la vista de la escasez de información existente para esta especie, dispersa y a veces errónea, se sintetiza la información corológica disponible, y se ofrecen datos sobre fenología de los adultos y tipología general de los hábitats que ocupa. Desde el punto de vista taxonómico, se redefinen los caracteres diagnósticos de la especie y se ilustran diversos aspectos de la variabilidad morfológica intra e interpoblacional.

  9. Análisis de los factores que influyen en la aparición de complicaciones y supervivencia de los catéteres venosos centrales para hemodiálisis

    Directory of Open Access Journals (Sweden)

    Gabriel Eduardo Rajoy Fernández

    2014-03-01

    Full Text Available Una de las principales actividades de enfermería nefrológica en las unidades de hemodiálisis, es el cuidado de catéteres venosos centrales mediante el cumplimiento de un protocolo que hace especial hincapié en las medidas universales de asepsia durante su manipulación. Además existen otras variables que pueden influir en la aparición de complicaciones del catéter limitando su supervivencia. Objetivo: Los objetivos de este estudio fueron analizar los factores que pudieran influir en la aparición de complicaciones del catéter venoso central para hemodiálisis, y valorar las tasas de infección en nuestro centro. Material y método: Se realizó un estudio descriptivo de una cohorte, en la Unidad de Diálisis del Hospital Meixoeiro, entre enero de 1991 y octubre de 2012, con una muestra formada por 1231 catéteres. Resultados: Fueron implantados 1231 catéteres (1187 temporales y 44 tunelizados tipo Hikman. Los temporales, 78% en femoral, 18% en yugular, y 4 % en subclavia. Los Hikman, 40 en lado derecho y 4 en lado izquierdo. La duración media de los catéteres implantados fue de 17,7 ± 30,8 días (mediana 8 días. 88% no presentaron incidencias durante su colocación. Las principales causas de colocación fueron la IRA (56% y el fallo de acceso vascular previo (30%. La principal complicación dentro de las causas de retirada fue la obstrucción del catéter (15%, siendo la más grave la infección (6%. De los 1231 catéteres, 70 presentaron un episodio de infección a los 19,1±33,0 días de media, (mediana 1 días. Tasa de infección (2010-2012 de 0,75/1000 días de catéter. Conclusión: Concluimos que la aplicación de cuidados continuos y estandarizados mediante un protocolo que hace especial hincapié en la asepsia durante la conexión y desconexión del CVC da como resultado un bajo índice de infecciones en esta unidad.

  10. The Stock Market's Reaction to Unemployment News: Why Bad News is Usually Good for Stocks

    OpenAIRE

    John H. Boyd; Ravi Jagannathan; Jian Hu

    2001-01-01

    We find that on average an announcement of rising unemployment is 'good news' for stocks during economic expansions and 'bad news' during economic contractions. Thus stock prices usually increase on news of rising unemployment, since the economy is usually in an expansion phase. We provide an explanation for this phenomenon. Unemployment news bundles two primitive types of information relevant for valuing stocks: information about future interest rates and future corporate earnings and divide...

  11. Study of radon and thoron gas behaviour in the air at the commercial centers in Rio de Janeiro and Pocos de Caldas city; Estudo do comportamento dos gases radonio e toronio presentes no ar em centro comercial do Rio de Janeiro e Pocos de Caldas

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Carlos A.C. [Minas Gerais Univ., Belo Horizonte, MG (Brazil). Dept. de Engenharia Mecanica. Lab. de Robotica, Soldagem e Simulacao; Morales, Rudnei K; Santos, Victor C. dos . [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil); br, victorcs@ime eb; Cardoso, Domingos D [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)

    2005-07-01

    The radon is a radioactive gas. It occurs naturally in the atmosphere coming from the decay of radium, with emission of alpha particles. There are three radon isotopes more known, of which the most important under the environmental point of view is the Rn-222, whose half life is 3.82 days. The radon and their descendants are responsible by more than 40 % of the natural radioactive dose received for the human beings inside the building. In doses above 4 pCi/l, given as occupational dose, can cause among other diseases, the lung cancer. The main source of radon inside the building is the soil. The incidence of radon inside the building varies according to the soil composition, the materials employed in its construction, the inside air temperature and humidity, time during the day, season and the ventilation process designed. The work was realized at the commercial centers in Rio de Janeiro and Pocos de Caldas, for methodology confirmation. It was utilized the passive (track detectors) and active (two filters technique. Kusnetz technique, Tsivoglou technique and alpha spectrometry technique) methods. The objective of this work was to analyze the radon and thoron concentrations levels in order to supply parameters upon the quality of the air in those commercial centers. (author)

  12. Glucosilación no enzimática y complicaciones crónicas de la diabetes mellitus Non-enzymatic glycosylation and chronic complications of diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Jeddú Cruz Hernández

    2010-08-01

    Full Text Available INTRODUCCIÓN: la hiperglucemia es considerada hoy como un factor patogénico fundamental del desarrollo de las complicaciones neurovasculares diabéticas y, específicamente, desempeña un papel preponderante en el fenómeno de la glucosilación no enzimática y la formación de productos finales de la glucosilación avanzada. OBJETIVOS: describir los mecanismos de la formación de los productos finales de la glucosilación avanzada y su relación con las complicaciones de la diabetes mellitus. DESARROLLO: los productos finales de la glucosilación avanzada se producen por la reacción no enzimática de la glucosa y otros derivados glucados (glioxal, metilglioxal y 3-desoxiglucosona con grupos amino de proteínas de larga vida. La glucosilación altera la estructura, las propiedades físico-químicas y la función de las proteínas intracelulares y extracelulares. En la membrana basal de los pequeños vasos se produce un engrosamiento y una distorsión de su estructura, que ocasiona pérdida de la elasticidad de la pared vascular y una permeabilidad anormal de esta a las proteínas (disfunción endotelial, así como aumento de la génesis de especies reactivas del oxígeno. La unión de productos finales de la glucosilación avanzada a sus receptores de membrana favorece la producción citoquinas y factores de crecimiento por los macrófagos y células mesangiales. Todo lo anterior favorece al desarrollo de aterosclerosis. CONCLUSIONES: los productos finales de la glucosilación avanzada desempeñan un importante papel en el desarrollo de las complicaciones microvasculares y macrovasculares en el diabético. El control metabólico estricto de la glucemia y, en la actualidad, la terapéutica farmacológica con agentes que inhiben la formación de productos finales de la glucosilación avanzada o tienen acción antioxidante, constituyen alternativas terapéuticas para la prevención y solución del problema de las complicaciones crónicas de la

  13. Subsidies to the decommissioning of the first uranium mining and processing plant in Brazil - the case of the mineral industrial complex in Pocos de Caldas, Minas Gerais State

    International Nuclear Information System (INIS)

    Fernandes, Horst Richard Sebastian Monken

    1997-01-01

    The closure of an uranium mining and milling facility has the potential to cause risks (radiological and non-radiological) to the human health and to the environment as a whole; these risks may be incurred in the short as well in the long terms. The present work took the mining and milling facility of Pocos de Caldas, Minas Gerais - as a study case. The following aspects were covered by the work: analysis of the impacts associated to the facility operation; assessment of the geological processes involved in the mobilization of radioactive and non-radioactive pollutants from the main sources of these pollutants in the environment - the waste rock piles and the tailings dam; quantification of the resulting impacts associated to the emission of pollutants into the environment in future scenarios and establishment of remedial actions taking into account the risk reduction and the association costs. The main aspects arising from the study were: the wastes in the tailings dam are stratified in relation to metal and radionuclide concentrations, with the exception of 210 Pb and 226 Ra. The stratification is caused by the oxidation of the residual pyrite in the tailings, and is also related to metal and radionuclide concentrations in seepage water being higher in the upper zone and lower in the deeper zones. Sulfate anion was the only pollutant present in the seepage water to be detected in the groundwater below the tailings dam. Mathematical simulations taking into account the rest of the potential pollutants indicated the probability of groundwater contamination after 800 years. Direct liquid effluent releases into superficial waters are associated with a dose of about 8.0 mSv/y (conservative scenario) and less than 0.62 mSv/y (non-conservative scenario). If houses are built over the tailings, doses as high as 40 mSv/y and 8.0 mSv/y are to expected due to the Rn exhalation and external gamma respectively. Finally, covering the tailings dam with a clay layer 1.0 m thick

  14. Dancing for Parkinson Disease: A Randomized Trial of Irish Set Dancing Compared With Usual Care.

    Science.gov (United States)

    Shanahan, Joanne; Morris, Meg E; Bhriain, Orfhlaith Ni; Volpe, Daniele; Lynch, Tim; Clifford, Amanda M

    2017-09-01

    To examine the feasibility of a randomized controlled study design and to explore the benefits of a set dancing intervention compared with usual care. Randomized controlled design, with participants randomized to Irish set dance classes or a usual care group. Community based. Individuals with idiopathic Parkinson disease (PD) (N=90). The dance group attended a 1.5-hour dancing class each week for 10 weeks and undertook a home dance program for 20 minutes, 3 times per week. The usual care group continued with their usual care and daily activities. The primary outcome was feasibility, determined by recruitment rates, success of randomization and allocation procedures, attrition, adherence, safety, willingness of participants to be randomized, resource availability, and cost. Secondary outcomes were motor function (motor section of the Unified Parkinson's Disease Rating Scale), quality of life (Parkinson's Disease Questionnaire-39), functional endurance (6-min walk test), and balance (mini-BESTest). Ninety participants were randomized (45 per group). There were no adverse effects or resource constraints. Although adherence to the dancing program was 93.5%, there was >40% attrition in each group. Postintervention, the dance group had greater nonsignificant gains in quality of life than the usual care group. There was a meaningful deterioration in endurance in the usual care group. There were no meaningful changes in other outcomes. The exit questionnaire showed participants enjoyed the classes and would like to continue participation. For people with mild to moderately severe PD, set dancing is feasible and enjoyable and may improve quality of life. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  15. Abdominal actinomycosis: a report of three cases of this uncommon infection; Actinomicos abdominal: una infeccion poco frecuente. A proposito de tres casos

    Energy Technology Data Exchange (ETDEWEB)

    Ostiz, S.; Sanchez, C.; Jimenez, G.; Caballero, P.; Cordero, J. L.; Montes, M. [Hospital Virgen del Camino. Pamplona (Spain)

    1999-07-01

    Abdominal actinomycosis is a rare infection caused by Actinomyces, a grampositive bacterium that generally exists as a saprophyte in the oral cavity and colon. The diagnosis is usually difficult due to its low incidence and nonspecific clinical and radiological findings. We present three new cases of abdominal actinomycosis. The first involved several pelvic structures and abdominal wall. The second was detected in left hepatic lobe. In the third case, the infection was located in descending colon. We stress the wide range of presenting signs, describing the findings that, when taken together, suggest the correct diagnosis. (Author) 13 refs.

  16. Cardiac rehabilitation versus usual care for patients treated with catheter ablation for atrial fibrillation

    DEFF Research Database (Denmark)

    Risom, Signe S; Zwisler, Ann-Dorthe; Rasmussen, Trine Bernholdt

    2016-01-01

    ) versus 20.7mL kg(-1) min(-1), p of main effect=0.003, p of interaction between time and intervention=0.020). No significant difference between groups on Short Form-36 was found (53.8 versus 51.9 points, P=.20). Two serious adverse events (atrial fibrillation in relation to physical exercise and death...... unrelated to rehabilitation) occurred in the cardiac rehabilitation group versus one in the usual care group (death unrelated to intervention) (P=.56). In the cardiac rehabilitation group 16 patients versus 7 in the usual care group reported non-serious adverse events (P=.047). CONCLUSION: Comprehensive...

  17. Supportive psychodynamic psychotherapy versus treatment as usual for first-episode psychosis

    DEFF Research Database (Denmark)

    Rosenbaum, Bent; Harder, Susanne; Knudsen, Per

    2012-01-01

    manualized individual supportive psychodynamic psychotherapy (SPP) in addition to treatment as usual or with treatment as usual alone (TaU). Symptoms and functional outcomes were measured using the Positive and Negative Syndrome Scale (PANSS) and the Global Assessment of Functioning scale (GAF). The study.......000) and GAF(symptom) (p = 0.010) significantly favored SPP in combination with TaU over TaU alone. In spite of limitations, this study speaks in favor of including supportive psychodynamic psychotherapy in the treatment for patients with schizophrenic first-episode psychoses....

  18. Evolución de las complicaciones neurológicas en la cirugía de deformidades vertebrales en la infancia. [Outcome of neurological complications in spinal deformity in children

    Directory of Open Access Journals (Sweden)

    Miguel A. Godoy

    2015-01-01

    Full Text Available Introducción: Se llevó a cabo un estudio retrospectivo descriptivo con el propósito de evaluar cómo evolucionaron los pacientes que sufrieron trastornos neurológicos a causa de una cirugía de las cifoescoliosis en la infancia. Materiales y Métodos: Se evaluó a 9 pacientes sin alteraciones neurológicas previas, que presentaron complicaciones neurológicas luego de un procedimiento quirúrgico por escoliosis o cifosis, operados en nuestra institución, durante un período de 10 años. Resultados: las etiologías de las deformidades fueron: 4 escoliosis idiopáticas, 2 escoliosis congénitas, una secundaria a neurofibromatosis de tipo 1, una cifosis idiopática y una poslaminectomía por miofibrosarcomatosis. Cinco pacientes tuvieron episodios neurofisiológicos intraquirúrgicos. Todos requirieron, al menos, una segunda intervención quirúrgica para solucionar su patología de base. La lesión neurológica fue: lesión radicular (un caso y lesión del cordón medular (8 casos; 6 sufrieron una lesión medular completa (75% que se manifestó como una paresia bilateral y 2 (25%, una lesión medular incompleta con monoparesia, sólo 2 quedaron con vejiga neurogénica. Conclusión: la detección temprana de una complicación neurológica, su diagnóstico etiológico y la resolución quirúrgica mejoran la evolución neurológica del paciente, y evitan la secuela o disminuyen su gravedad.

  19. Effectiveness of Mindfulness-Based Group Therapy Compared to the Usual Opioid Dependence Treatment.

    Science.gov (United States)

    Imani, Saeed; Atef Vahid, Mohammad Kazem; Gharraee, Banafsheh; Noroozi, Alireza; Habibi, Mojtaba; Bowen, Sarah

    2015-06-01

    This study investigated the effectiveness of mindfulness-based group therapy (MBGT) compared to the usual opioid dependence treatment (TAU).Thirty outpatients meeting the DSM-IV-TR criteria for opioid dependence from Iranian National Center for Addiction Studies (INCAS) were randomly assigned into experimental (Mindfulness-Based Group Therapy) and control groups (the Usual Treatment).The experimental group undertook eight weeks of intervention, but the control group received the usual treatment according to the INCAS program. The Five Factor Mindfulness Questionnaire (FFMQ) and the Addiction Sevier Index (ASI) were administered at pre-treatment and post-treatment assessment periods. Thirteen patients from the experimental group and 15 from the control group completed post-test assessments. The results of MANCOVA revealed an increase in mean scores in observing, describing, acting with awareness, non-judging, non-reacting, and decrease in mean scores of alcohol and opium in MBGT patient group. The effectiveness of MBGT, compared to the usual treatment, was discussed in this paper as a selective protocol in the health care setting for substance use disorders.

  20. Mandometer Treatment Not Superior to Treatment as Usual for Anorexia Nervosa

    NARCIS (Netherlands)

    van Elburg, Annemarie A.; Hillebrand, Jacquelien J. G.; Huyser, Chaim; Snoek, Maartje; Kas, Martien; Hoek, Hans W.; Adan, Roger A. H.

    Objective: A comparison of the efficacy of a novel treatment method for anorexia nervosa (AN), the Mandometer treatment (MT), with treatment as usual (TAU). Method: During treatment data were collected to determine weight recovery and outcome as assessed by the Morgan Russell Outcome Assessment

  1. Effects of circuit training as alternative to usual physiotherapy after stroke: randomised controlled trial

    NARCIS (Netherlands)

    van de Port, I.G.L.; Wevers, L.E.G.; Lindeman, E.; Kwakkel, G.

    2012-01-01

    Objective: To analyse the effect of task oriented circuit training compared with usual physiotherapy in terms of self reported walking competency for patients with stroke discharged from a rehabilitation centre to their own home. Design: Randomised controlled trial with follow-up to 24 weeks.

  2. Costs of terminal patients who receive palliative care or usual care in different hospital wards.

    Science.gov (United States)

    Simoens, Steven; Kutten, Betty; Keirse, Emmanuel; Berghe, Paul Vanden; Beguin, Claire; Desmedt, Marianne; Deveugele, Myriam; Léonard, Christian; Paulus, Dominique; Menten, Johan

    2010-11-01

    In addition to the effectiveness of hospital care models for terminal patients, policy makers and health care payers are concerned about their costs. This study aims to measure the hospital costs of treating terminal patients in Belgium from the health care payer perspective. Also, this study compares the costs of palliative and usual care in different types of hospital wards. A multicenter, retrospective cohort study compared costs of palliative care with usual care in acute hospital wards and with care in palliative care units. The study enrolled terminal patients from a representative sample of hospitals. Health care costs included fixed hospital costs and charges relating to medical fees, pharmacy and other charges. Data sources consisted of hospital accountancy data and invoice data. Six hospitals participated in the study, generating a total of 146 patients. The findings showed that palliative care in a palliative care unit was more expensive than palliative care in an acute ward due to higher staffing levels in palliative care units. Palliative care in an acute ward is cheaper than usual care in an acute ward. This study suggests that palliative care models in acute wards need to be supported because such care models appear to be less expensive than usual care and because such care models are likely to better reflect the needs of terminal patients. This finding emphasizes the importance of the timely recognition of the need for palliative care in terminal patients treated in acute wards.

  3. Effectiveness of Mindfulness-Based Group Therapy Compared to the Usual Opioid Dependence Treatment

    Directory of Open Access Journals (Sweden)

    Saeed Imani

    2015-11-01

    Full Text Available  Objective: This study investigated the effectiveness of mindfulness-based group therapy (MBGT compared to the usual opioid dependence treatment (TAU.Thirty outpatients meeting the DSM-IV-TR criteria for opioid dependence from Iranian National Center for Addiction Studies (INCAS were randomly assigned into experimental (Mindfulness-Based Group Therapy and control groups (the Usual Treatment.The experimental group undertook eight weeks of intervention, but the control group received the usual treatment according to the INCAS program.  Methods:The Five Factor Mindfulness Questionnaire (FFMQ and the Addiction Sevier Index (ASI were administered at pre-treatment and post-treatment assessment periods. Thirteen patients from the experimental group and 15 from the control group completed post-test assessments. Results:The results of MANCOVA revealed an increase in mean scores in observing, describing, acting with awareness, non-judging, non-reacting, and decrease in mean scores of alcohol and opium in MBGT patient group. Conclusion:The effectiveness of MBGT, compared to the usual treatment, was discussed in this paper as a selective protocol in the health care setting for substance use disorders.

  4. Manual acupuncture plus usual care versus usual care alone in the treatment of endometriosis-related chronic pelvic pain: study protocol for a randomised controlled feasibility study.

    Science.gov (United States)

    Armour, Mike; Smith, Caroline A; Schabrun, Siobhan; Steiner, Genevieve Z; Zhu, Xiaoshu; Lawson, Kenny; Song, Jing

    2018-01-01

    Endometriosis is the most common cause of chronic pelvic pain worldwide. Non-surgical treatments are effective for only 30-50% of women and have a significant side effect burden that leads to high discontinuation rates. Surgery can be effective but is expensive and invasive, and symptoms tend to recur within 5 years. There is early evidence that acupuncture may be effective in treating endometriosis-related chronic pelvic pain, showing clinically significant analgesia. Both levels of inflammation and pain processing have been shown to be altered in women with chronic pelvic pain. Acupuncture has been shown to reduce inflammation and change central pain processing in other conditions, but research on women with endometriosis is currently lacking. The aim of this feasibility study is to provide data on recruitment rates, retention, appropriateness of outcome measures, minimal clinically important difference in numeric rated scales for pain and the potential effect of acupuncture on pain processing and markers of inflammation in endometriosis-related CPP. We will include women aged 18-45 years with a diagnosis of endometriosis via laparoscopy in the past 5 years. A total of 30 participants will be recruited and randomly allocated in a 1:1 ratio to receive acupuncture or usual care. Women in the acupuncture group will receive two 45-min treatment sessions per week for 8 weeks (total of 16 sessions). Women in the usual care group will continue with their current treatment regimen. The primary feasibility outcomes are recruitment rates, retention rates and the safety and acceptability of the intervention; secondary patient-centred outcomes include a change in 0-10 daily pelvic pain ratings, the Endometriosis Health Profile 30 (EHP-30) and changes in conditioned pain modulation, resting and task-related EEG activity and inflammatory markers. Analyses will be performed blind to group allocation. This is a two-armed, assessor blind, randomised controlled feasibility

  5. Secondary prevention after minor stroke and TIA - usual care and development of a support program.

    Directory of Open Access Journals (Sweden)

    Stefanie Leistner

    Full Text Available Effective methods of secondary prevention after stroke or TIA are available but adherence to recommended evidence-based treatments is often poor. The study aimed to determine the quality of secondary prevention in usual care and to develop a stepwise modeled support program.Two consecutive cohorts of patients with acute minor stroke or TIA undergoing usual outpatient care versus a secondary prevention program were compared. Risk factor control and medication adherence were assessed in 6-month follow-ups (6M-FU. Usual care consisted of detailed information concerning vascular risk factor targets given at discharge and regular outpatient care by primary care physicians. The stepwise modeled support program additionally employed up to four outpatient appointments. A combination of educational and behavioral strategies was employed.168 patients in the observational cohort who stated their openness to participate in a prevention program (mean age 64.7 y, admission blood pressure (BP: 155/84 mmHg and 173 patients participating in the support program (mean age 67.6 y, BP: 161/84 mmHg were assessed at 6 months. Proportions of patients with BP according to guidelines were 50% in usual-care and 77% in the support program (p<0.01. LDL<100 mg/dl was measured in 62 versus 71% (p = 0.12. Proportions of patients who stopped smoking were 50 versus 79% (p<0.01. 72 versus 89% of patients with atrial fibrillation were on oral anticoagulation (p = 0.09.Risk factor control remains unsatisfactory in usual care. Targets of secondary prevention were met more often within the supported cohort. Effects on (cerebro-vascular recurrence rates are going to be assessed in a multicenter randomized trial.

  6. Treatment-as-usual (TAU) is anything but usual: a meta-analysis of CBT versus TAU for anxiety and depression.

    Science.gov (United States)

    Watts, Sarah E; Turnell, Adrienne; Kladnitski, Natalie; Newby, Jill M; Andrews, Gavin

    2015-04-01

    There were three aims of this study, the first was to examine the efficacy of CBT versus treatment-as-usual (TAU) in the treatment of anxiety and depressive disorders, the second was to examine how TAU is defined in TAU control groups for those disorders, and the third was to explore whether the type of TAU condition influences the estimate of effects of CBT. A systematic search of Cochrane Central Register of Controlled Trials, PsycINFO, and CINAHL was conducted. 48 studies of CBT for depressive or anxiety disorders (n=6926) that specified that their control group received TAU were identified. Most (n=45/48) provided an explanation of the TAU group however there was significant heterogeneity amongst TAU conditions. The meta-analysis showed medium effects favoring CBT over TAU for both anxiety (g=0.69, 95% CI 0.47-0.92, pCBT is superior to TAU and the size of the effect of CBT compared to TAU depends on the nature of the TAU condition. The term TAU is used in different ways and should be more precisely described. The four key details to be reported can be thought of as "who, what, how many, and any additional treatments?" Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Aqueous speciation and the importance of particulate phase in hydro-geochemistry behaviour of U,Th and REE from uranium mine and Morro do Ferro, Pocos de Caldas - Brazil

    International Nuclear Information System (INIS)

    Jesus, Honerio Coutinho de

    1996-04-01

    This work, which was realized within the Natural Analogue Project Pocos de Caldas, had as its main objective the study of the colloidal behavior of U, Th, REE and some other elements of geochemical interest, in surface and groundwaters from the Osamu Utsumi mine and the Morro do ferro in Pocos de Caldas, Minas Gerais. Ultrafiltration techniques with flat membranes of different molecular mass exclusion limits (100 K, 10 K e 1K daltons) were used for this purpose. In addition, suspended matter (>0,45 μm), retained during pre-filtering of the waters, was analysed mineralogically and chemically (U, Th, REE, isotopic composition of U and Th, etc). Studies of the chemical composition of colloidal particles (<0,45 μm) and their size distributions were performed using ESCA and SEM, respectively. In addition, speciation studies by means of the MINEQL computation program were made to obtain information about the principal complexed species of relevant elements and the formation of solid phases. All the above mentioned investigations were aimed at better understanding of the migration and sorption behavior of U, Th and REE in both environments. The data obtained in this work indicate a low importance of particulate phases (colloids or suspended particles) for the migration behavior of U, Th and REE in waters from the Osumu Utsumi uranium mine and the Morro do ferro. However, these particles, composed mainly of ferric oxyhydrates and humic compounds, play an important role in sorption and immobilization processes. (author)

  8. The feasibility of a pragmatic randomised controlled trial to compare usual care with usual care plus individualised homeopathy, in children requiring secondary care for asthma.

    Science.gov (United States)

    Thompson, E A; Shaw, A; Nichol, J; Hollinghurst, S; Henderson, A J; Thompson, T; Sharp, D

    2011-07-01

    To test the feasibility of a pragmatic trial design with economic evaluation and nested qualitative study, comparing usual care (UC) with UC plus individualised homeopathy, in children requiring secondary care for asthma. This included recruitment and retention, acceptability of outcome measures patients' and health professionals' views and experiences and a power calculation for a definitive trial. In a pragmatic parallel group randomised controlled trial (RCT) design, children on step 2 or above of the British Thoracic Society Asthma Guidelines (BTG) were randomly allocated to UC or UC plus a five visit package of homeopathic care (HC). Outcome measures included the Juniper Asthma Control Questionnaire, Quality of Life Questionnaire and a resource use questionnaire. Qualitative interviews were used to gain families' and health professionals' views and experiences. 226 children were identified from hospital clinics and related patient databases. 67 showed an interest in participating, 39 children were randomised, 18 to HC and 21 to UC. Evidence in favour of adjunctive homeopathic treatment was lacking. Economic evaluation suggests that the cost of additional consultations was not offset by the reduced cost of homeopathic remedies and the lower use of primary care by children in the homeopathic group. Qualitative data gave insights into the differing perspectives of families and health care professionals within the research process. A future study using this design is not feasible, further investigation of a potential role for homeopathy in asthma management might be better conducted in primary care with children with less severe asthma. Copyright © 2011 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  9. Characterization of the geochemical processes present in the radionuclides and metals mobilization in the tailing dam at the Uranium Mining and Milling Facilities - Pocos de Caldas, MG, Brazil; Caracterizacao dos processos geoquimicos atuantes na mobilizacao de radionuclideos e metais na bacia de rejeitos do complexo minero-industrial de Pocos de Caldas, MG, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Patricia Freitas

    1995-08-01

    In Brazil, the first step of nuclear fuel cycle - the mining and milling of the uranium ore - is developed at the Uranium Mining and Milling Facilities of Pocos de Caldas, Minas Gerais state. The wastes management is a very important aspect of the process. The understanding of the geochemical processes that occur in the tailings dam is a key question to define a plan of action concerning the decommissioning strategy of the facility. The objective of the present work was to give some issues to help in the adoption of the remedial actions concerning the decommissioning of the facility. It focused on the characterization of the most important geochemical processes regulating the mobilization of radionuclides and heavy metals in the tailings dam. Two cores from the tailings dam (uncovered area) were collected. Seepage and drainage waters were sampled, the same being true for the tailings dam lake. Groundwater form an aquifer bellow the tailings dam and superficial waters from a river that receives the effluents of the dam (Soberbo River) were also sampled. Data from the mining company were used to calculate the inventory of radionuclides and heavy metals deposited in the waste dam.The obtained results showed that pyrite oxidation is the key process in the mobilization of radionuclides and heavy metals from the wastes. Pyrite oxidation is a process regulated by oxygen diffusion and water. In the studied scenario it could be shown that the process was limited to a one meter deep layer in the uncovered part of the waste dam. Because of this, Fe, Al, Mn, Zn, Th and {sup 238} U showed higher concentrations in the bottom layers of the cores in relation to the upper ones. {sup 226} Ra and {sup 210} Pb showed opposite patterns. The coprecipitation with Ca SO{sub 4} was the most relevant mechanism in both radionuclides immobilization in the wastes. Sulfate was the only chemical species that could be assigned as a contaminant in aquifer bellow the waste dam. As a conclusion, the

  10. Predicting therapy success for treatment as usual and blended treatment in the domain of depression.

    Science.gov (United States)

    van Breda, Ward; Bremer, Vincent; Becker, Dennis; Hoogendoorn, Mark; Funk, Burkhardt; Ruwaard, Jeroen; Riper, Heleen

    2018-06-01

    In this paper, we explore the potential of predicting therapy success for patients in mental health care. Such predictions can eventually improve the process of matching effective therapy types to individuals. In the EU project E-COMPARED, a variety of information is gathered about patients suffering from depression. We use this data, where 276 patients received treatment as usual and 227 received blended treatment, to investigate to what extent we are able to predict therapy success. We utilize different encoding strategies for preprocessing, varying feature selection techniques, and different statistical procedures for this purpose. Significant predictive power is found with average AUC values up to 0.7628 for treatment as usual and 0.7765 for blended treatment. Adding daily assessment data for blended treatment does currently not add predictive accuracy. Cost effectiveness analysis is needed to determine the added potential for real-world applications.

  11. The effects of cognitive therapy versus 'treatment as usual' in patients with major depressive disorder

    DEFF Research Database (Denmark)

    Jakobsen, Janus Christian; Lindschou Hansen, Jane; Storebø, Ole Jakob

    2011-01-01

    BACKGROUND: Major depressive disorder afflicts an estimated 17% of individuals during their lifetimes at tremendous suffering and costs. Cognitive therapy may be an effective treatment option for major depressive disorder, but the effects have only had limited assessment in systematic reviews....... METHODS/PRINCIPAL FINDINGS: Cochrane systematic review methodology, with meta-analyses and trial sequential analyses of randomized trials, are comparing the effects of cognitive therapy versus 'treatment as usual' for major depressive disorder. To be included the participants had to be older than 17 years....... Meta-analysis on the data from the Hamilton Rating Scale for Depression showed that cognitive therapy compared with 'treatment as usual' significantly reduced depressive symptoms (mean difference -2.15 (95% confidence interval -3.70 to -0.60; P

  12. The Kramers-Kronig relations for usual and anomalous Poisson-Nernst-Planck models

    OpenAIRE

    Evangelista, Luiz Roberto; Lenzi, Ervin Kaminski; Barbero, Giovanni

    2013-01-01

    The consistency of the frequency response predicted by a class of electrochemical impedance expressions is analytically checked by invoking the Kramers-Kronig (KK) relations. These expressions are obtained in the context of Poisson-Nernst-Planck usual (PNP) or anomalous (PNPA) diffusional models that satisfy Poisson's equation in a finite-length situation. The theoretical results, besides being successful in interpreting experimental data, are also shown to obey the KK relations when these re...

  13. The Kramers–Kronig relations for usual and anomalous Poisson–Nernst–Planck models

    International Nuclear Information System (INIS)

    Evangelista, Luiz Roberto; Lenzi, Ervin Kaminski; Barbero, Giovanni

    2013-01-01

    The consistency of the frequency response predicted by a class of electrochemical impedance expressions is analytically checked by invoking the Kramers–Kronig (KK) relations. These expressions are obtained in the context of Poisson–Nernst–Planck usual or anomalous diffusional models that satisfy Poisson’s equation in a finite length situation. The theoretical results, besides being successful in interpreting experimental data, are also shown to obey the KK relations when these relations are modified accordingly. (paper)

  14. The Kramers-Kronig relations for usual and anomalous Poisson-Nernst-Planck models.

    Science.gov (United States)

    Evangelista, Luiz Roberto; Lenzi, Ervin Kaminski; Barbero, Giovanni

    2013-11-20

    The consistency of the frequency response predicted by a class of electrochemical impedance expressions is analytically checked by invoking the Kramers-Kronig (KK) relations. These expressions are obtained in the context of Poisson-Nernst-Planck usual or anomalous diffusional models that satisfy Poisson's equation in a finite length situation. The theoretical results, besides being successful in interpreting experimental data, are also shown to obey the KK relations when these relations are modified accordingly.

  15. Outcomes of usual chiropractic, harm & efficacy, the ouch study: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Walker Bruce F

    2011-10-01

    Full Text Available Abstract Background Previous studies have demonstrated that adverse events occur during chiropractic treatment. However, because of these studies design we do not know the frequency and extent of these events when compared to sham treatment. The principal aims of this study are to establish the frequency and severity of adverse effects from short term usual chiropractic treatment of the spine when compared to a sham treatment group. The secondary aim of this study is to establish the efficacy of usual short term chiropractic care for spinal pain when compared to a sham intervention. Methods One hundred and eighty participants will be randomly allocated to either usual chiropractic care or a sham intervention group. To be considered for inclusion the participants must have experienced non-specific spinal pain for at least one week. The study will be conducted at the clinics of registered chiropractors in Western Australia. Participants in each group will receive two treatments at intervals no less than one week. For the usual chiropractic care group, the selection of therapeutic techniques will be left to the chiropractors' discretion. For the sham intervention group, de-tuned ultrasound and de-tuned activator treatment will be applied by the chiropractors to the regions where spinal pain is experienced. Adverse events will be assessed two days after each appointment using a questionnaire developed for this study. The efficacy of short term chiropractic care for spinal pain will be examined at two week follow-up by assessing pain, physical function, minimum acceptable outcome, and satisfaction with care, with the use of the following outcome measures: Numerical Rating Scale, Functional Rating Index, Neck Disability Index, Minimum Acceptable Outcome Questionnaire, Oswestry Disability Index, and a global measure of treatment satisfaction. The statistician, outcome assessor, and participants will be blinded to treatment allocation. Trial

  16. H eat transfer betw een tw o surfaces usually in- creases w h en th e ...

    Indian Academy of Sciences (India)

    Srimath

    H eat transfer betw een tw o surfaces usually in- creases w h en th e tem p eratu re d i® eren ce b etw een the tw o surfaces increases. H ere w e highlight an unusual situation in radiation heat transfer w herein the heat transfer decreases w hen the tem perature di®erence increases. In tro d u ctio n. In 1701,N ew ton ...

  17. Do you really know precise radiologic–pathologic correlation of usual interstitial pneumonia?

    Energy Technology Data Exchange (ETDEWEB)

    Johkoh, Takeshi, E-mail: johkoht@aol.com [Department of Radiology, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, Itami (Japan); Sumikawa, Hiromotsu [Department of Radiology, Osaka University Graduate School of Medicine, Suita (Japan); Fukuoka, Junya; Tanaka, Tomonori [Department of Pathology, Nagasaki University Graduate School of Medicine, Toyama (Japan); Fujimoto, Kiminori [Department of Radiology and Center for Diagnostic Imaging, Kurume University School of Medicine, Kurume (Japan); Takahashi, Masashi [Department of Radiology, Shiga Medical University, Otsu (Japan); Tomiyama, Noriyuki [Department of Radiology, Osaka University Graduate School of Medicine, Suita (Japan); Kondo, Yasuhiro; Taniguchi, Hiroyuki [Department of Respiratory and Allergic Medicine, Tosei General Hospital, Seto (Japan)

    2014-01-15

    Although usual interstitial pneumonia (UIP) is the most common chronic interstitial pneumonia, understanding of pathologic backgrounds of CT findings has still not been enough. Since honeycombing on either scanning microgram or CT is essential for diagnosis of UIP in 2010 ATS-ERS-JRS-ALAT guide line, the role of radiologists has become much more important. We will summarize common and uncommon CT findings with radiologic–pathological correlation.

  18. Therapy recommendation "act as usual" in patients with whiplash injuries QTF I°.

    Science.gov (United States)

    Dehner, Christoph; Kraus, Michael; Schöll, Hendrik; Schneider, Florian; Richter, Peter; Kramer, Michael

    2012-08-20

    Up to now no therapy study has used the classification system of the Quebec Task Force (QTF) to differentiate between patients with (QTF II°) and without functional disorders (QTF I°). This differentiation seems meaningful, as this difference may be relevant for the correct treatment planning. In this context the effect of the therapy recommendation "act as usual" has been evaluated in a homogeneous patient collective with whiplash injuries QTF I°. 470 patients with acute whiplash injuries had been catched in this study and classified according to the QTF. 359 patients (76.4%) with QTF I° injuries could be identified. Out of that 162 patients were enrolled to the study and received the therapy recommendation "act as usual" and the adapted pain treatment with non-steroidal anti-inflammatory drugs (NSAID). After six months the outcome was evaluated by phone. After injury the median pain score assessed by a visual analogue scale (VAS) was 5.4 (min = 3.3; max = 8.5). After six months 5 of the 162 patients complained intermittent pain symptoms (VAS values < 2). This is consistent with a chronification rate of 3.1%. After injury, the median pain disability index (PDI) was 3.9 (min = 1.9; max = 7.7). After six months 3 of the 162 patients stated persisting disability during sporting and physical activities (VAS values < 1). The therapy recommendation "act as usual" in combination with an adapted pain treatment is sufficient. Usually patients with whiplash injuries QTF I° do not need physical therapy. An escalation of therapy measures should be reserved to patients with complicated healing processes.

  19. Usual Dietary Energy Density Distribution Is Positively Associated with Excess Body Weight in Mexican Children.

    Science.gov (United States)

    Aburto, Tania C; Cantoral, Alejandra; Hernández-Barrera, Lucia; Carriquiry, Alicia L; Rivera, Juan A

    2015-07-01

    Studies suggest a positive association between dietary energy density (DED) and body weight in adults, but evidence in children is inconclusive. The objective of this study was to compare usual DED distributions of nonoverweight vs. overweight or obese (OW/O) Mexican children. The study used 24-h recall (24HR) data from 2367 children aged 5-11 y from the 2012 Mexican National Health and Nutrition Survey (ENSANUT 2012). Repeated 24HR measures were obtained in a random sample (∼10%) to estimate usual intake distributions by using the Iowa State University (PC-Side) method. Implausible dietary reports were identified. Multivariate linear regression models were used to evaluate the relation between DED and body mass index status and to compare results with and without PC-Side adjustment and restriction to plausible reporters. A total of 35.1% of the children in the sample were OW/O. The usual DED mean was ∼175 kcal/100 g in both the complete sample and the plausible reporters subsample. Regression models adjusted by PC-Side and for potential confounders showed higher DED in OW/O relative to nonoverweight children for both plausible reporters (9.7 kcal/100 g; n = 1452, P 0.10). A positive association between usual DED and OW/O was found in Mexican children. The association was stronger when only plausible reporters were considered. This suggests that there is a need for strategies to reduce energy density in the diet of Mexican children. © 2015 American Society for Nutrition.

  20. Future reef decalcification under a business-as-usual CO2 emission scenario.

    Science.gov (United States)

    Dove, Sophie G; Kline, David I; Pantos, Olga; Angly, Florent E; Tyson, Gene W; Hoegh-Guldberg, Ove

    2013-09-17

    Increasing atmospheric partial pressure of CO2 (pCO2) is a major threat to coral reefs, but some argue that the threat is mitigated by factors such as the variability in the response of coral calcification to acidification, differences in bleaching susceptibility, and the potential for rapid adaptation to anthropogenic warming. However the evidence for these mitigating factors tends to involve experimental studies on corals, as opposed to coral reefs, and rarely includes the influence of multiple variables (e.g., temperature and acidification) within regimes that include diurnal and seasonal variability. Here, we demonstrate that the inclusion of all these factors results in the decalcification of patch-reefs under business-as-usual scenarios and reduced, although positive, calcification under reduced-emission scenarios. Primary productivity was found to remain constant across all scenarios, despite significant bleaching and coral mortality under both future scenarios. Daylight calcification decreased and nocturnal decalcification increased sharply from the preindustrial and control conditions to the future scenarios of low (reduced emissions) and high (business-as-usual) increases in pCO2. These changes coincided with deeply negative carbonate budgets, a shift toward smaller carbonate sediments, and an increase in the abundance of sediment microbes under the business-as-usual emission scenario. Experimental coral reefs demonstrated highest net calcification rates and lowest rates of coral mortality under preindustrial conditions, suggesting that reef processes may not have been able to keep pace with the relatively minor environmental changes that have occurred during the last century. Taken together, our results have serious implications for the future of coral reefs under business-as-usual environmental changes projected for the coming decades and century.

  1. Do you really know precise radiologic–pathologic correlation of usual interstitial pneumonia?

    International Nuclear Information System (INIS)

    Johkoh, Takeshi; Sumikawa, Hiromotsu; Fukuoka, Junya; Tanaka, Tomonori; Fujimoto, Kiminori; Takahashi, Masashi; Tomiyama, Noriyuki; Kondo, Yasuhiro; Taniguchi, Hiroyuki

    2014-01-01

    Although usual interstitial pneumonia (UIP) is the most common chronic interstitial pneumonia, understanding of pathologic backgrounds of CT findings has still not been enough. Since honeycombing on either scanning microgram or CT is essential for diagnosis of UIP in 2010 ATS-ERS-JRS-ALAT guide line, the role of radiologists has become much more important. We will summarize common and uncommon CT findings with radiologic–pathological correlation.

  2. Adequacy of Usual Vitamin and Mineral Intake in Spanish Children and Adolescents: ENALIA Study

    Directory of Open Access Journals (Sweden)

    Ana M. López-Sobaler

    2017-02-01

    Full Text Available Background: The National Dietary Survey on the Child and Adolescent Population in Spain (ENALIA provides data to assess the usual micronutrient intake among Spanish infants, children, and adolescents. Methods: Cross-sectional survey (November 2012–July 2014 of a representative sample of Spanish children and adolescents (six months–17 years (n = 1862. Dietary information was collected using two non-consecutive one-day food diaries (six months–10 years old or two 24 h dietary recalls (11 years and older separated by at least 14 days. Estimates were calculated using the Iowa State University method and PC-SIDE software (version 1.0, department of statistics, center for agricultural and rural development, Ames, IA, USA to account for within- and between-person variation. Results: Usual intake of vitamin D was insufficient in practically all individuals. Vitamin E, folate, and calcium were insufficient, especially from nine years of age, and magnesium and iodine from 14 years of age. The percentage of subjects with insufficient intakes was higher among females. Sodium intake was excessive in a considerable percentage of the population, especially in males, and it increased with age. Finally, over half of children under four years of age had zinc usual intakes that exceeded the Tolerable Upper Level. Conclusion: Vitamin and mineral intake in Spain should be improved, especially in late childhood and adolescence. Nutritional intervention and educational strategies are needed to promote healthy eating habits and correct micronutrient inadequacies in Spanish children and adolescents.

  3. COMPLICACIONES PSIQUIÁTRICAS DEL ABORTO

    OpenAIRE

    Manuel Gurpegui; Dolores Jurado

    2009-01-01

    Introducción: Las consecuencias psiquiátricas del aborto inducido siguen siendo objeto de controversia. Las reacciones de cualquier mujer al descubrir que ha concebido pueden ser muy variables. El embarazo, inicialmente intencionado o no deseado, puede provocar estrés; y el aborto espontáneo puede acarrear sentimientos de pérdida y reacciones de duelo, por lo que no es de extrañar que el aborto inducido, con las implicaciones emocionales añadidas (sentimientos de alivio, vergüenza y culpa), s...

  4. Usual Dietary Intakes: SAS Macros for Estimating Ratios of Two Dietary Components that are Consumed Nearly Every Day

    Science.gov (United States)

    The following SAS macros can be used to create a bivariate distribution of usual intake of two dietary components that are consumed nearly every day and to calculate percentiles of the population distribution of the ratio of usual intakes.

  5. Acupuncture, Counseling, and Usual care for Depression (ACUDep: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    MacPherson Hugh

    2012-11-01

    Full Text Available Abstract Background The evidence on the effect of acupuncture or counseling for depression is not conclusive yet is sufficient to warrant further research. Our aim is to conduct a full-scale RCT to determine the clinical and cost effectiveness of acupuncture and counseling compared to usual care alone. We will explore the experiences and perspectives of patients and practitioners. Methods/Design Randomized controlled trial with three parallel arms: acupuncture plus usual care, counseling plus usual care, and usual care alone, in conjunction with a nested qualitative study using in-depth interviews with purposive samples of trial participants. Participants: Patients aged over 18 years diagnosed with depression or mood disorder by their GP and with a score of 20 or above on the Beck Depression Inventory (BDI-II. Randomization: Computer randomization by York Trials Unit to acupuncture, counseling, and usual care alone in proportions of 2:2:1, respectively, with secure allocation concealment. Interventions: Patients allocated to acupuncture and counseling groups receive the offer of up to 12 weekly sessions. Both interventions allow flexibility to address patient variation, yet are constrained within defined protocols. Acupuncture is based on traditional Chinese medicine and counseling is non-directive within the humanistic tradition. Outcome: The PHQ-9 is the primary outcome measure, collected at baseline, 3, 6, 9, and 12 months. Also measured is BDI-II, SF-36 Bodily pain subscale, and EQ-5D. Texted mood scores are collected weekly over the first 15 weeks. Health-related resource use is collected over 12 months. Analysis: The sample size target was for 640 participants, calculated for an effect size of 0.32 on the PHQ-9 when comparing acupuncture with counseling given 90% power, 5% significance, and 20% loss to follow-up. Analysis of covariance will be used on an intention-to-treat basis. Thematic analysis will be used for qualitative data. We will

  6. Appreciation of environmental risks analysis methodologies in the offshore well drilling activities; Analise de metodologias na avaliacao de riscos ambientais relacionados as atividades de perfuracao de pocos maritimos

    Energy Technology Data Exchange (ETDEWEB)

    Zampolli, Daniella M. [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil); Morooka, Celso K. [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Engenharia de Petroleo

    2004-07-01

    Nowadays, the projects of products and processes are supposed to integrate environmental risks criteria, in addition to their inherent operation impacts. Industrial activities, in general, generate risks to the environment, and, in case of incidents occurrence, many of the possible consequences can be translated into serious impacts. The Risk Analysis is destined to act as a decision tool in the environmental area, and therefore, the use of one of these during the project phase of an enterprise becomes important, aiming the guarantee of the system reliability. The present article has the purpose of analyzing methodologies that are being employed for the environmental risk analysis, as well as usual procedures applied in the oil industry, specially for the offshore wells drilling, evaluating and discussing their peculiarities and possible improvement. It was intended to obtain a general overview of risk analysis methodologies, with the objective of verifying the existence of some characteristics that would positively contribute for the knowledge of the inherent risks in the activities of petroleum installations, where this kind of learning is something extremely technically necessary and legally mandatory. (author)

  7. El control de la diabetes mellitus y sus complicaciones en Medellín, Colombia, 2001-2003 Controlling diabetes mellitus and its complications in Medellín, Colombia, 2001-2003

    Directory of Open Access Journals (Sweden)

    Alberto Villegas Perrasse

    2006-12-01

    Full Text Available OBJETIVOS: Identificar las principales características sociodemográficas, clínicas y conductuales de los pacientes que participaban en los programas de atención al diabético en Medellín, Colombia, y evaluar el cumplimiento de las metas de control metabólico y de los estándares de control en el diabético. MÉTODOS: Se realizó un estudio descriptivo transversal mediante el análisis de las historias clínicas de todos los pacientes que asistían a los programas de atención al diabético desde al menos 6 meses en nueve instituciones de salud entre enero de 2001 y diciembre de 2003. Se tomaron datos sociodemográficos (edad y sexo, clínicos (tiempo de evolución de la enfermedad, tipo y tratamiento de la diabetes y enfermedades concurrentes y su tratamiento, sobre los hábitos de vida (práctica de ejercicios físicos, hábito de fumar y consumo de azúcar y grasas y sobre las complicaciones crónicas y los resultados de las pruebas de laboratorio del último año. Todos los datos confusos o faltantes se registraron como ausentes. RESULTADOS: De las 3 583 historias clínicas evaluadas, se logró conocer el tipo de diabetes que padecían 3 554 pacientes, de ellos 95,1% correspondieron a pacientes con diabetes tipo 2. En general, 56,9% (intervalo de confianza de 95% [IC95%]: 55,2 a 58,6% de los pacientes realizaban ejercicios periódicos; 15,1% (IC95%: 13,9 a 16,3% aún fumaba en el momento del corte, 17,7% (IC95%: 16,4 a 19,0% había dejado de fumar y 67,2% (IC95%: 65,6 a 68,8% nunca había fumado. En total, 21,0% (IC95%: 19,6 a 22,5% de los pacientes consumía azúcar regularmente, mientras 24,8% (IC95%: 23,3 a 26,3% consumía grasas y solo 19,5% (IC95%: 17,8 a 21,3% realizaba automonitoreo de la glucemia con una frecuencia semanal o mayor. La prevalencia general de hipertensión arterial fue de 68,8% y de 98,2% de dislipidemia en los diabéticos tipo 2. El promedio general del índice de masa corporal fue de 28,0 kg/m² (IC95%: 27,8 a

  8. Effects of Structured Versus Usual Care on Renal Endpoint in Type 2 Diabetes: The SURE Study

    Science.gov (United States)

    Chan, Juliana C.; So, Wing-Yee; Yeung, Chun-Yip; Ko, Gary T.; Lau, Ip-Tim; Tsang, Man-Wo; Lau, Kam-Piu; Siu, Sing-Chung; Li, June K.; Yeung, Vincent T.; Leung, Wilson Y.; Tong, Peter C.

    2009-01-01

    OBJECTIVE Multifaceted care has been shown to reduce mortality and complications in type 2 diabetes. We hypothesized that structured care would reduce renal complications in type 2 diabetes. RESEARCH DESIGN AND METHODS A total of 205 Chinese type 2 diabetic patients from nine public hospitals who had plasma creatinine levels of 150–350 μmol/l were randomly assigned to receive structured care (n = 104) or usual care (n = 101) for 2 years. The structured care group was managed according to a prespecified protocol with the following treatment goals: blood pressure triglyceride 500 μmol/l or dialysis). RESULTS Of these 205 patients (mean ± SD age 65 ± 7.2 years; disease duration 14 ± 7.9 years), the structured care group achieved better control than the usual care group (diastolic blood pressure 68 ± 12 vs. 71 ± 12 mmHg, respectively, P = 0.02; A1C 7.3 ± 1.3 vs. 8.0 ± 1.6%, P structured care (23.1%, n = 24) and usual care (23.8%, n = 24; NS) groups had similar end points, but more patients in the structured care group attained ≥3 treatment goals (61%, n = 63, vs. 28%, n = 28; P < 0.001). Patients who attained ≥3 treatment targets (n = 91) had reduced risk of the primary end point (14 vs. 34; relative risk 0.43 [95% CI 0.21–0.86] compared with that of those who attained ≤2 targets (n = 114). CONCLUSIONS Attainment of multiple treatment targets reduced the renal end point and death in type 2 diabetes. In addition to protocol, audits and feedback are needed to improve outcomes. PMID:19460913

  9. Usual Choline Intakes Are Associated with Egg and Protein Food Consumption in the United States

    Directory of Open Access Journals (Sweden)

    Taylor C. Wallace

    2017-08-01

    Full Text Available Choline is an essential nutrient with critical roles in several biological processes including neuronal development, cell signaling, nerve impulse transmission, and lipid transport and metabolism. The National Cancer Institute method was used to assess usual intakes of choline from foods according to data for participants enrolled in the National Health and Nutrition Examination Survey 2009–2014 datasets and pregnant women in the 2005–2014 datasets. Suboptimal intakes of choline are present across many gender and life-stage subpopulations, as well as pregnant women in the U.S. Only 8.03 ± 0.56% of adults and 8.51 ± 2.89% pregnant women meet the AI for choline. Children 2–3 years were the most likely to meet their gender and life-stage specific AI, followed by children 4–8 years. Adults 19+ years who consume eggs were more likely to meet their gender and life-stage AI as compared to non-consumers (57.3 ± 1.45% and 2.43 ± 0.28%. Consumers of eggs had almost double the usual intake of choline as compared to non-consumers (525 ± 5.17 mg/d and 294 ± 1.98; p < 0.0001. Protein food (meat, poultry and seafood consumption also increased usual choline intakes compared to non-consumers (345 ± 2.21 mg/day and 235 ± 8.81; p < 0.0001 to a lesser degree, but did not result in substantial increases in the percent of individuals meeting the AI. No subpopulation exceeded the UL for choline. This research illustrates that it is extremely difficult to achieve the AI for choline without consuming eggs or taking a dietary supplement.

  10. Comparative experimental and numerical studies of usual insulation materials and PCMs in buildings at Casablanca

    Science.gov (United States)

    Mourid, Amina; El Alami, Mustapha

    2018-05-01

    In this paper, we present a comparative thermal study of the usual insulation materials used in the building as well as the innovate one like phase change materials (PCMs). Both experimental study and numerical approach were applied in this work for summer season. In the experimental study the PCM was installed on the outer surface on the ceiling of one of two full-scale rooms located at FSAC, Casablanca. A simulation model was performed with TRNSYS’17 software. We have established as a criterion of comparison the internal temperatures. An economic study also has been carried out. Based on this latter, that the PCM is most efficient.

  11. PRECISE - pregabalin in addition to usual care for sciatica: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Mathieson, Stephanie; Maher, Christopher G; McLachlan, Andrew J; Latimer, Jane; Koes, Bart W; Hancock, Mark J; Harris, Ian; Day, Richard O; Pik, Justin; Jan, Stephen; Billot, Laurent; Lin, Chung-Wei Christine

    2013-07-11

    Sciatica is a type of neuropathic pain that is characterised by pain radiating into the leg. It is often accompanied by low back pain and neurological deficits in the lower limb. While this condition may cause significant suffering for the individual, the lack of evidence supporting effective treatments for sciatica makes clinical management difficult. Our objectives are to determine the efficacy of pregabalin on reducing leg pain intensity and its cost-effectiveness in patients with sciatica. PRECISE is a prospectively registered, double-blind, randomised placebo-controlled trial of pregabalin compared to placebo, in addition to usual care. Inclusion criteria include moderate to severe leg pain below the knee with evidence of nerve root/spinal nerve involvement. Participants will be randomised to receive either pregabalin with usual care (n = 102) or placebo with usual care (n = 102) for 8 weeks. The medicine dosage will be titrated up to the participant's optimal dose, to a maximum 600 mg per day. Follow up consultations will monitor individual progress, tolerability and adverse events. Usual care, if deemed appropriate by the study doctor, may include a referral for physical or manual therapy and/or prescription of analgesic medication. Participants, doctors and researchers collecting participant data will be blinded to treatment allocation. Participants will be assessed at baseline and at weeks 2, 4, 8, 12, 26 and 52. The primary outcome will determine the efficacy of pregabalin in reducing leg pain intensity. Secondary outcomes will include back pain intensity, disability and quality of life. Data analysis will be blinded and by intention-to-treat. A parallel economic evaluation will be conducted from health sector and societal perspectives. This study will establish the efficacy of pregabalin in reducing leg pain intensity in patients with sciatica and provide important information regarding the effect of pregabalin treatment on disability and quality of life

  12. Business as usual in spite of the CO2 trade of the EU

    International Nuclear Information System (INIS)

    Wellander, Dag

    2004-01-01

    The trade system that is going to be launched by the EU at the turn of the year (2004/2005) has some serious shortcomings as it was originally formulated. It is limited to the EU. It is only partial; it applies only to emission sources in the energy sector and some energy-intensive sectors. Both limitations raise the costs of cutting down on the emissions, which would have hit the EU unilaterally. According to the author, work is now in progress to make the trade system as inefficient as possible, aiming at ''business as usual''. The climate problems cannot be solved without global cooperation, which is not in sight

  13. Giant solitary fibrous tumour of the pleura: a rare but usually benign intrathoracic neoplasm

    DEFF Research Database (Denmark)

    Bodtger, Uffe; Pedersen, Jesper Holst; Skov, Birgit Guldhammer

    2009-01-01

    BACKGROUND: Low forced expiratory volume (FEV(1)) and low performance status usually preclude surgical treatment of lung neoplasms. Earlier case reports have suggested that curative, safe surgery is possible in extrapulmonal intrathoracic neoplasms. METHODS: A case report of an 83-year-old women...... with progressing dyspnoea secondary to a huge left-side neoplasm. RESULTS: Work-up reveal an FEV(1) of 0.4 L, and a giant solitary fibrous tumor of the pleura. The tumor was surgically removed in toto without complications: weighting approximately 3 kg, and benign histology. The patient was without dyspnoea...

  14. Increasing the amount of usual rehabilitation improves activity after stroke: a systematic review

    Directory of Open Access Journals (Sweden)

    Emma J Schneider

    2016-10-01

    Full Text Available Questions: In people receiving rehabilitation aimed at reducing activity limitations of the lower and/or upper limb after stroke, does adding extra rehabilitation (of the same content as the usual rehabilitation improve activity? What is the amount of extra rehabilitation that needs to be provided to achieve a beneficial effect? Design: Systematic review with meta-analysis of randomised trials. Participants: Adults aged 18 years or older that had a diagnosis of stroke. Intervention: Extra rehabilitation with the same content as usual rehabilitation aimed at reducing activity limitations of the lower and/or upper limb. Outcome measures: Activity measured as lower or upper limb ability. Results: A total of 14 studies, comprising 15 comparisons, met the inclusion criteria. Pooling data from all the included studies showed that extra rehabilitation improved activity immediately after the intervention period (SMD = 0.39, 95% CI 0.07 to 0.71, I2 = 66%. When only studies with a large increase in rehabilitation (> 100% were included, the effect was greater (SMD 0.59, 95% CI 0.23 to 0.94, I2 = 44%. There was a trend towards a positive relationship (r = 0.53, p = 0.09 between extra rehabilitation and improved activity. The turning point on the ROC curve of false versus true benefit (AUC = 0.88, p = 0.04 indicated that at least an extra 240% of rehabilitation was needed for significant likelihood that extra rehabilitation would improve activity. Conclusion: Increasing the amount of usual rehabilitation aimed at reducing activity limitations improves activity in people after stroke. The amount of extra rehabilitation that needs to be provided to achieve a beneficial effect is large. Trial registration: PROSPERO CRD42012003221. [Schneider EJ, Lannin NA, Ada L, Schmidt J (2016 Increasing the amount of usual rehabilitation improves activity after stroke: a systematic review. Journal of Physiotherapy 62: 182–187

  15. Skin care education and individual counselling versus treatment as usual in healthcare workers with hand eczema

    DEFF Research Database (Denmark)

    Ibler, K.S.; Jemec, G.B.E.; Thomsen, S.F.

    2012-01-01

    Objective: To evaluate the effect of a secondary prevention programme with education on skin care and individual counselling versus treatment as usual in healthcare workers with hand eczema. Design: Randomised, observer blinded parallel group superiority clinical trial. Setting: Three hospitals...... in Denmark. Participants: 255 healthcare workers with self reported hand eczema within the past year randomised centrally and stratified by profession, severity of eczema, and hospital. 123 were allocated to the intervention group and 132 to the control group. Interventions: Education in skin care...

  16. Usual alcohol consumption and suicide mortality among the Korean elderly in rural communities: Kangwha Cohort Study.

    Science.gov (United States)

    Yi, Sang-Wook; Jung, Myoungjee; Kimm, Heejin; Sull, Jae-Woong; Lee, Eunsook; Lee, Kwang Ok; Ohrr, Heechoul

    2016-08-01

    The evidence from prospective studies on whether greater usual alcohol consumption is associated with a higher risk of death by suicide in the general population is inconclusive. 6163 participants (2635 men; 3528 women) in a 1985 survey among rural residents in Korea aged 55 years and above were followed until 2008. A Cox model was used to calculate HRs of suicide death after adjustment for demographic, socioeconomic and health-related confounders. 37 men and 24 women died by suicide. Elderly persons who consumed alcohol daily, 70 g alcohol (5 drinks) or more per drinking day, or 210 g alcohol (15 drinks) or more per week had higher suicide mortality (prisk of suicide death, respectively. Women had a higher relative risk of suicide death associated with alcohol consumption, compared with men. A greater frequency and amount of usual alcohol consumption was linearly associated with higher suicide death. Given the same amount of alcohol consumption, women might have a higher relative risk of suicide than men. Our findings support 'the lower the better' for alcohol intake, no protective effect of moderate alcohol consumption, and a sex-specific guideline (lower alcohol threshold for women) as actions to prevent suicide death. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  17. Depressed mood, usual activity level, and continued employment after starting dialysis.

    Science.gov (United States)

    Kutner, Nancy G; Zhang, Rebecca; Huang, Yijian; Johansen, Kirsten L

    2010-11-01

    When patients start dialysis, their employment rate declines and disability benefits are an option. With patient sociodemographic and clinical characteristics including disability income status controlled, we investigated the significance of depressed mood and usual activity level as predictors of patients' continued employment after dialysis start. Incident patients from 296 randomly selected dialysis clinics were surveyed in the Comprehensive Dialysis Study (CDS). Participants provided information about employment status, disability income status, education, depressive symptoms measured by the Patient Health Questionnaire-2 (PHQ-2), and usual activity level/energy expenditure measured by the Human Activity Profile. Age, gender, race, insurance, diabetes, inability to ambulate or transfer, chronic obstructive pulmonary disease, cardiovascular conditions, and hemoglobin and serum albumin values at treatment start were obtained from US Renal Data System files. Dialysis modality was defined at time of interview. Among 585 CDS participants who worked in the previous year, 191 (32.6%) continued working after dialysis start. On the basis of the PHQ-2 cutoff score ≥3, 12.1% of patients who remained employed had possible or probable depression, compared with 32.8% of patients who were no longer employed. In adjusted analyses, higher Human Activity Profile scores were associated with increased likelihood of continued employment, and there was a borderline association between lower PHQ-2 scores and continued employment. Screening and management of depressive symptoms and support for increased activity level may facilitate patients' opportunity for continued employment after dialysis start, along with generally improving their overall quality of life.

  18. Mindfulness based cognitive therapy versus treatment as usual in adults with attention deficit hyperactivity disorder (ADHD).

    Science.gov (United States)

    Janssen, Lotte; Kan, Cornelis C; Carpentier, Pieter J; Sizoo, Bram; Hepark, Sevket; Grutters, Janneke; Donders, Rogier; Buitelaar, Jan K; Speckens, Anne E M

    2015-09-15

    Adults with attention deficit hyperactivity disorder (ADHD) often present with a lifelong pattern of core symptoms that is associated with impairments of functioning in daily life. This has a substantial personal and economic impact. In clinical practice there is a high need for additional or alternative interventions for existing treatments, usually consisting of pharmacotherapy and/or psycho-education. Although previous studies show preliminary evidence for the effectiveness of mindfulness-based interventions in reducing ADHD symptoms and improving executive functioning, these studies have methodological limitations. This study will take account of these limitations and will examine the effectiveness of Mindfulness Based Cognitive Therapy (MBCT) in further detail. A multi-centre, parallel-group, randomised controlled trial will be conducted in N = 120 adults with ADHD. Patients will be randomised to MBCT in addition to treatment as usual (TAU) or TAU alone. Assessments will take place at baseline and at three, six and nine months after baseline. Primary outcome measure will be severity of ADHD symptoms rated by a blinded clinician. Secondary outcome measures will be self-reported ADHD symptoms, executive functioning, mindfulness skills, self-compassion, positive mental health and general functioning. In addition, a cost-effectiveness analysis will be conducted. This trial will offer valuable information about the clinical and cost-effectiveness of MBCT in addition to TAU compared to TAU alone in adults swith ADHD. ClinicalTrials.gov NCT02463396. Registered 8 June 2015.

  19. Medical teleconferencing with high-definition video presentation on the 'usual' Internet.

    Science.gov (United States)

    Obuchi, Toshiro; Shima, Hiroji; Iwasaki, Akinori

    2013-06-01

    Although medical teleconferences on advanced academic networks have been common (Telemed J E Health 15:112-117, 1; Asian J Endosc Surg 3:185-188, 2; Surg Today 41:1579-1581, 3; Telemedicine development center of Asia. http://www.aqua.med.kyushu-u.ac.jp/eg/index.html . Accessed 6 March 2013, 4), reports regarding 'usual' Internet teleconferences or tele-lectures employing a telecommunication system for business use are very rare. Medical teleconferences and tele-lectures on the Internet were held three times between our institutions and other institutions, using the 'HD Com' made by Panasonic (HD Com. http://panasonic.biz/com/visual/ . Accessed 6 March 2013, 5), which is a high-definition telecommunication system for business tele-meeting. All of our medical telecommunications were successfully completed without any troubles. This system allows for all kinds of presentations using personal computers to be made from each station, so that discussions with high-definition surgical video presentation, which has recently been developed, could be effortlessly established despite the distance between institutions. Unlike telecommunication using advanced academic networks, this system can run without any need for specific engineering support, on the usual Internet. Medical telecommunication employing this system is likely to become common among ordinary hospitals in the near future.

  20. Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension.

    Science.gov (United States)

    Rothwell, Peter M

    2010-03-13

    Although hypertension is the most prevalent treatable vascular risk factor, how it causes end-organ damage and vascular events is poorly understood. Yet, a widespread belief exists that underlying usual blood pressure can alone account for all blood-pressure-related risk of vascular events and for the benefits of antihypertensive drugs, and this notion has come to underpin all major clinical guidelines on diagnosis and treatment of hypertension. Other potentially informative measures, such as variability in clinic blood pressure or maximum blood pressure reached, have been neglected, and effects of antihypertensive drugs on such measures are largely unknown. Clinical guidelines recommend that episodic hypertension is not treated, and the potential risks of residual variability in blood pressure in treated hypertensive patients have been ignored. This Review discusses shortcomings of the usual blood-pressure hypothesis, provides background to accompanying reports on the importance of blood-pressure variability in prediction of risk of vascular events and in accounting for benefits of antihypertensive drugs, and draws attention to clinical implications and directions for future research. Copyright 2010 Elsevier Ltd. All rights reserved.

  1. Electronic Health Record for Intensive Care based on Usual Windows Based Software.

    Science.gov (United States)

    Reper, Arnaud; Reper, Pascal

    2015-08-01

    In Intensive Care Units, the amount of data to be processed for patients care, the turn over of the patients, the necessity for reliability and for review processes indicate the use of Patient Data Management Systems (PDMS) and electronic health records (EHR). To respond to the needs of an Intensive Care Unit and not to be locked with proprietary software, we developed an EHR based on usual software and components. The software was designed as a client-server architecture running on the Windows operating system and powered by the access data base system. The client software was developed using Visual Basic interface library. The application offers to the users the following functions: medical notes captures, observations and treatments, nursing charts with administration of medications, scoring systems for classification, and possibilities to encode medical activities for billing processes. Since his deployment in September 2004, the EHR was used to care more than five thousands patients with the expected software reliability and facilitated data management and review processes. Communications with other medical software were not developed from the start, and are realized by the use of basic functionalities communication engine. Further upgrade of the system will include multi-platform support, use of typed language with static analysis, and configurable interface. The developed system based on usual software components was able to respond to the medical needs of the local ICU environment. The use of Windows for development allowed us to customize the software to the preexisting organization and contributed to the acceptability of the whole system.

  2. A Randomized Trial Comparing Acupuncture, Simulated Acupuncture, and Usual Care for Chronic Low Back Pain

    Science.gov (United States)

    Cherkin, Daniel C.; Sherman, Karen J.; Avins, Andrew L.; Erro, Janet H.; Ichikawa, Laura; Barlow, William E.; Delaney, Kristin; Hawkes, Rene; Hamilton, Luisa; Pressman, Alice; Khalsa, Partap S.; Deyo, Richard A.

    2009-01-01

    Background Acupuncture is a popular complementary and alternative treatment for chronic back pain. Recent European trials suggest similar short-term benefits from real and sham acupuncture needling. This trial addresses the importance of needle placement and skin penetration in eliciting acupuncture effects for patients with chronic low back pain. Methods 638 adults with chronic mechanical low back pain were randomized to: individualized acupuncture, standardized acupuncture, simulated acupuncture, or usual care. Ten treatments were provided over 7 weeks by experienced acupuncturists. The primary outcomes were back-related dysfunction (Roland Disability score, range: 0 to 23) and symptom bothersomeness (0 to 10 scale). Outcomes were assessed at baseline and after 8, 26 and 52 weeks. Results At 8 weeks, mean dysfunction scores for the individualized, standardized, and simulated acupuncture groups improved by 4.4, 4.5, and 4.4 points, respectively, compared with 2.1 points for those receiving usual care (P0.05). Conclusions Although acupuncture was found effective for chronic low back pain, tailoring needling sites to each patient and penetration of the skin appear to be unimportant in eliciting therapeutic benefits. These findings raise questions about acupuncture’s purported mechanisms of action. It remains unclear whether acupuncture, or our simulated method of acupuncture, provide physiologically important stimulation or represent placebo or non-specific effects. PMID:19433697

  3. 020. Coexistence of lung adenocarcinoma and usual interstitial pneumonia: a case report

    Science.gov (United States)

    Baliaka, Aggeliki; Papaemmanouil, Styliani; Spyratos, Dionysis; Zarogoulidis, Paul; Sakkas, Leonidas

    2015-01-01

    Background Usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing interstitial pneumonia of unknown cause. The most common symptoms are progressively increased shortness of breath and dry cough. Some studies suggest an association between usual interstitial pneumonia and lung cancer through different pathogenetic mechanisms. Objective The case presentation of a patient with lung adenocarcinoma and UIP. Methods A 66-year-old male presented with persistent dry cough, hemoptysis and dyspnea. The chest radiographs revealed a mass in the lower lobe of the left lung, measuring 3 cm, as well as diffuse interstitial changes in the same lobe. Two partial lobectomies were performed. Results Histological examination of the mass showed moderately differentiated adenocarcinoma, focally with bronchoalveolar pattern (Immunohistochemical detection of EGFR: positive). The rest lung parenchyma presented histological appearance of UIP. Conclusions According to clinicopathological studies, the prevalence of lung cancer among patients with UIP/IPF varies between 4% and 9%. The overall median survival of IPF-Ca patients is seven months in comparison with IPF only patients (14 months).

  4. Supervised progressive cross-continuum strength training compared with usual care in older medical patients

    DEFF Research Database (Denmark)

    Pedersen, Mette Merete; Petersen, Janne; Beyer, Nina

    2016-01-01

    Background: Hospitalization in older adults is characterized by physical inactivity and a risk of losing function and independence. Systematic strength training can improve muscle strength and functional performance in older adults. Few studies have examined the effect of a program initiated during...... hospitalization and continued after discharge. We conducted a feasibility study prior to this trial and found a progression model for loaded sit-to-stands feasible in older medical patients. This study aims to determine whether a simple supervised strength training program for the lower extremities (based...... on the model), combined with post-training protein supplementation initiated during hospitalization and continued at home for 4 weeks, is superior to usual care on change in mobility 4 weeks after discharge in older medical patients. Methods: Eighty older medical patients (65 years or older) acutely admitted...

  5. Survey of Usual Practice: Dysphagia Therapy in Head & Neck Cancer Patients

    Science.gov (United States)

    Krisciunas, Gintas P.; Sokoloff, William; Stepas, Katherine; Langmore, Susan E.

    2012-01-01

    There is no standardized dysphagia therapy for head and neck cancer patients and scant evidence to support any particular protocol, leaving institutions and individual speech language pathologists (SLPs) to determine their own protocols based on “typical” practices or anecdotal evidence. To gain an understanding of current usual practices, a national internet-based survey was developed and disseminated to SLPs who treat HNC patients. From a random sample of 4,000 ASHA SID 13 members, 1,931 fit the inclusion criteria, and 759 complete responses were recorded for a 39.3% response rate. Results were analyzed by institution type as well as by individual clinical experience. While some interesting trends emerged from the data, a lack of uniformity and consensus regarding best practices was apparent. This is undoubtedly due to a paucity of research adequately addressing the efficacy of any one therapy for dysphagia in the HNC population. PMID:22456699

  6. From Sustainability-as-usual to Sustainability Excellence in Local Bioenergy Business

    Directory of Open Access Journals (Sweden)

    Heli Kasurinen

    2017-06-01

    Full Text Available Bioenergy business operators can significantly contribute to the sustainability of bioenergy systems. While research has addressed the maturity of corporate responsibility for sustainability, the maturity levels of bioenergy business have not been determined. The objectives of this research were to characterise the maturity levels of bioenergy corporate responsibility for sustainability and outline an approach by which companies can operate at the most mature sustainability excellence level. Literature, three workshops attended by bioenergy experts and a case study on biobutanol production in Brazil were used to develop the maturity model and approach. The results characterise the profitability, acceptability, and sustainability orientation maturity levels through sustainability questions and methods, and list the components of a systemic, holistic approach. Although the shift of business mindset from sustainability-as-usual to sustainability excellence is challenging, a systemic approach is necessary to broadly identify sustainability questions and a multitude of methods by which they can be answered.

  7. A 'business-as-usual' energy scenario for France at the 2020 vista

    International Nuclear Information System (INIS)

    Giraud, P.N.

    2000-01-01

    A 'business-as-usual' energy scenario is the most probable scenario where the energy demand follows the trends of the past and where no new energy policy is implemented. This work is a complement to the three contrasted energy scenarios built in 1998 by the 'Energy 2010-2020' prospective group of the French general commission of national development. The scenario built in this study is only a reference which allows the measure the efforts made to reach political goals. The main conclusion of this scenario is the increase of the CO 2 emissions under the double effect of the economic growth and of the cessation of the nuclear program which becomes non-competitive with respect to the gas prices and actualization rates retained in the scenario. The main constraint of the energy future is incontestably the necessary fight against the greenhouse effect. (J.S.)

  8. Allocation of energy resources for power generation in India: Business as usual and energy efficiency

    International Nuclear Information System (INIS)

    Mallah, Subhash; Bansal, N.K.

    2010-01-01

    This paper deals with MARKAL allocations for various energy sources, in India, for Business As Usual (BAU) scenario and for the case of exploitation of energy saving potential in various sectors of economy. In the BAU scenario, the electrical energy requirement will raise up to 5000 bKwh units per year or 752 GW of installed capacity with major consumers being in the industry, domestic and service sectors. This demand can be met by a mix of coal, hydro, nuclear and wind technologies. Other reneawbles i.e. solar and biomass will start contributing from the year 2040 onwards. By full exploitation of energy saving potential, the annual electrical energy demand gets reduced to 3061 bKwh (or 458 GW), a reduction of 38.9%.The green house gas emissions reduce correspondingly. In this scenario, market allocations for coal, gas and large hydro become stagnant after the year 2015.

  9. Remission and rheumatoid arthritis: Data on patients receiving usual care in twenty-four countries

    DEFF Research Database (Denmark)

    Sokka, Tuulikki; Hetland, Merete Lund; Mäkinen, Heidi

    2008-01-01

    and lowest remission rates was >/=15% in 10 countries, 5-14% in 7 countries, and definition of remission, male sex, higher education, shorter disease duration, smaller number of comorbidities, and regular......OBJECTIVE: To compare the performance of different definitions of remission in a large multinational cross-sectional cohort of patients with rheumatoid arthritis (RA). METHODS: The Questionnaires in Standard Monitoring of Patients with RA (QUEST-RA) database, which (as of January 2008) included 5......,848 patients receiving usual care at 67 sites in 24 countries, was used for this study. Patients were clinically assessed by rheumatologists and completed a 4-page self-report questionnaire. The database was analyzed according to the following definitions of remission: American College of Rheumatology (ACR...

  10. Remission and rheumatoid arthritis: Data on patients receiving usual care in twenty-four countries

    DEFF Research Database (Denmark)

    Sokka, Tuulikki; Hetland, Merete Lund; Mäkinen, Heidi

    2008-01-01

    and lowest remission rates was >/=15% in 10 countries, 5-14% in 7 countries, and generally low remission rates [definition of remission, male sex, higher education, shorter disease duration, smaller number of comorbidities, and regular......OBJECTIVE: To compare the performance of different definitions of remission in a large multinational cross-sectional cohort of patients with rheumatoid arthritis (RA). METHODS: The Questionnaires in Standard Monitoring of Patients with RA (QUEST-RA) database, which (as of January 2008) included 5......,848 patients receiving usual care at 67 sites in 24 countries, was used for this study. Patients were clinically assessed by rheumatologists and completed a 4-page self-report questionnaire. The database was analyzed according to the following definitions of remission: American College of Rheumatology (ACR...

  11. How to distinguish between 'business as usual' and 'significant business disruptions' and plan accordingly.

    Science.gov (United States)

    Halliwell, Peter

    2008-01-01

    This paper seeks to provide an insight into Air New Zealand and how business continuity is managed in an industry with inherent disruptions. The differences between 'business as usual' and 'significant business disruptions' are outlined along with their associated criteria, response and escalation processes. The paper describes why the company incorporates the four 'R's of the Civil Defence Emergency Management Act within its BCM framework and how this aids resilience. A case study is provided that details a 'significant disruption' that occurred in November 2006. This event resulted in the total loss of a sales office and cargo shed after unrest in the Kingdom of Tonga escalated to widespread rioting, looting and destruction of their central business district. The lessons from this event have been captured and provide some essential mitigation measures that will assist in future events.

  12. Disease progression in usual interstitial pneumonia compared with desquamative interstitial pneumonia. Assessment with serial CT

    International Nuclear Information System (INIS)

    Hartman, T.E.; Primack, S.L.; Kang, E.Y.

    1997-01-01

    Objective. To determine the outcome of areas of ground-glass attenuation and assess disease progression on serial high-resolution CT (HRCT) scans of patients with biopsy specimen-proved usual interstitial pneumonia (UIP) and desquamative interstitial pneumonia (DIP). Materials and methods. Twelve patients with biopsy specimen-proved UIP and 11 patients with biopsy specimen-proved DIP who had initial and follow-up HRCT scans (median interval, 10 months) were reviewed. Eleven patients with UIP and 11 with DIP received treatment between the initial and follow-up CT scans. The scans were evaluated for the presence and extent of ground-glass attenuation, irregular linear opacities and honeycombing, and overall extent of parenchymal involvement. Results. On initial CT scans, all 12 patients with UIP had areas of ground-glass attenuation (mean±SD extent, 30±16%) and irregular lines (mean±SD extent, 17±7%) and 10 patients had honeycombing (mean±SD extent, 10±6%). All 11 patients with DIP had areas of ground-glass attenuation on initial HRCT scans (mean±SD extent, 51±26%), 5 patients had irregular linear opacities (mean±SD extent, 5±5%), and 1 patient had honeycombing. Nine of the 12 patients with UIP showed increase in the extent of ground-glass attenuation (n=6) or progression to irregular lines (n=2) or honeycombing (n=4) on follow-up as compared with only 2 patients with DIP who showed progression to irregular lines (n=1) or honeycombing (n=1) (p 2 test). Conclusion. In patients with UIP, areas of ground-glass attenuation usually increase in extent or progress to fibrosis despite treatment. Areas of ground-glass attenuation in most patients with DIP remain stable or improve with treatment. (authors)

  13. Asociación entre el estado de infección por VIH y complicaciones infecciosas poscesárea electiva Association between HIV infection status and infectious complications after an elective c-section

    Directory of Open Access Journals (Sweden)

    Romina Tejada

    2012-12-01

    Full Text Available Objetivos. Determinar la asociación entre VIH y complicaciones infecciosas (CI después de una cesárea electiva. Materiales y métodos. Estudio de cohortes no concurrentes; se revisaron las historias clínicas de 237 cesáreas electivas en gestantes VIH reactivas atendidas en el Instituto Nacional Materno Perinatal de Perú, realizadas entre 2004 a 2012. Estas fueron pareadas por cirujano y fecha de cesárea con 237 gestantes VIH no reactivas. Se recogieron datos sociodemográficos, clínicos, características de la cesárea y relacionados a la infección por el VIH. Las CI se evaluaron según las recomendaciones del NHI Consensus Development Task Force. Se realizó el análisis bivariado con un nivel de significación del 5% y el cálculo del Odds Ratio (OR con intervalo de confianza (IC al 95%. Se construyó un modelo de regresión logística condicional. Resultados. El 13,9% de mujeres VIH positivas presentaron CI y 9,7% del grupo control (OR: 1,5 IC95% [0,9-2,7]; las expuestas (mujeres con VIH tuvieron mayor probabilidad de tener una infección del tracto urinario (ITU que las no expuestas (ORa: 4,5 IC95% [1,4-14,5]. Se encontró asociación entre CI y el tipo de incisión (ORa: 2,3 IC95% [1,1-4,5] y el tiempo de hospitalización (6 frente a 3 días, pObjectives: To determine the connection between HIV and infectious complications (IC after an elective C-section. Materials and methods. A non-concurrent cohort study was conducted, in which the clinical records of 237 elective C-sections on HIV-positive pregnant women who gave birth at the Instituto Nacional Materno Perinatal (National Maternal Perinatal Institute between 2004 and 2012 were revised. The records were matched by surgeon and C-section date, with 237 HIV-negative pregnant women. Socio-demographic and clinical data were collected, along with characteristics of the C-section and data related to the HIV infection. IC were evaluated according to the NIH Consensus Development Task

  14. Factores de riesgo y complicaciones crónicas en el diagnóstico reciente de la diabetes tipo 2 Risk factors and chronic complications in the newly diagnosis of type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Isaac Salama Benarroch

    2001-08-01

    Full Text Available Se pesquisó la frecuencia de complicaciones crónicas en pacientes con diabetes tipo 2 en el momento del diagnóstico y se evaluó la asociación con factores de riesgo como enfermedad cardiovascular, hipertensión arterial, obesidad, dislipidemia y factores bioquímicos asociados. Se estudiaron durante 3 meses, 24 casos con edades entre 30 y 70 años en los servicios de Diabetología y Nutrición, Cardiología y Retina del Hospital Municipal de Oftalmología "Dr. Pedro Lagleyze" de Buenos Aires. Se estudió perfil metabólico, microalbuminuria, fondo de ojo, vascular periférico, neurológico, tensión arterial y obesidad. Se comprobó que la edad promedio fue 50 años. Hallazgos: neuropatía: 5 (25 %: nefropatía: 3 (12,5 %; retinopatía: 6 (25 %; cardiopatía y enfermedad vascular periférica: 13 (54 %; hipertensión arterial: 13 (54 %; obesidad: 3 (12,5 %; hipercolesterolemia: 14 (58 %; LDLc elevado: 12 (50 %; HDLc bajo: 10 (41,6 %; hiperviscosidad sanguínea: 6 (25 %; hemoglobina glucosilada elevada 18 (75 %; hipertrigliceridemia: 7 (29, 7 %. Se halló que el 100 % de los pacientes tenían factores de riesgo asociados a la diabetes. Se consideró necesario promover la educación pública sobre diabetes, pesquisar los factores asociados y tratar de forma agresiva y precoz la hiperglucemia y los factores bioquímicos agregadosThe frequency of chronic complications in patients with type 2 diabetes at the time of diagnosis was screened and their association with risk factors such as cardiovascular disease, blood hypertension, obesity, dislipidemia and related biochemical factors were evaluated. During three months, 24 cases aged 30-70 years were studied by the Diabetology and Nutrition Service, Cardiology and Retina Services of "Dr Pedro Lagleyze" Municipal Ophthalmology Hospital in Buenos Aires. Metabolic, peripheral vascular and neurologic profiles, microalbuminuria, fundus oculi, blood pressure and obesity were studied. It was proved that

  15. INFLUENCE OF USUAL AND DUAL WHEELS ON SOIL PENETRATION RESISTANCE: THE GIS-APPROACH

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    Zhukov A. V.

    2015-12-01

    Full Text Available GIS-APPROACH application has allowed establishing that usual wheels of machine-tractor units carry out considerable influence on soil which exceeds visible borders of a track of wheels on the dimensions. This influence shows in augmentation of soil penetration resistance at 100-155 % in comparison with the control on depth of 0-10 cm and on 20-30 % on depth of 45-50 %. It is impossible to exclude that influence of wheels proceeds more deeply, than tests have been conducted. Critical for cultivated plants value of soil penetration resistance in 3 MPa under the influence of usual wheels of agricultural machinery comes nearer practically to a surface. Character of profile changes of hardness in various regions influences of wheels allows assuming the long season of a relaxation of soil for achievement of background values of soil penetration resistance. The further researches are necessary for an establishment of concrete indicators of dynamics. Negative influence of an overstocking does not confine only deterioration of conditions of growth of assemblages of rootlets of plants. Infringement of processes of moving of moisture in the soil, the accelerated evaporation and the slowed down processes of a filtration and an infiltration, destruction of modular frame, activization of erosive processes is possible. The understanding of these processes will give the chance volume understanding of real influence of running systems of machine-tractor devices on bedrock. Region intensive influence of dual wheels is circumscribed by the top soil layers (0-15 cm. The major feature of influence of dual wheels is absence of an overstocking above critical levels. It is impossible to exclude possible positive influence of moderate inspissations of soil under the influence of dual wheels for growth of agricultural crops and moisture conservation in soil. The cumulative negative effect on soil crossed vehicles traces is probable. The long season of a relaxation of

  16. Effects of business-as-usual anthropogenic emissions on air quality

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    A. Pozzer

    2012-08-01

    Full Text Available The atmospheric chemistry general circulation model EMAC has been used to estimate the impact of anthropogenic emission changes on global and regional air quality in recent and future years (2005, 2010, 2025 and 2050. The emission scenario assumes that population and economic growth largely determine energy and food consumption and consequent pollution sources with the current technologies ("business as usual". This scenario is chosen to show the effects of not implementing legislation to prevent additional climate change and growing air pollution, other than what is in place for the base year 2005, representing a pessimistic (but plausible future.

    By comparing with recent observations, it is shown that the model reproduces the main features of regional air pollution distributions though with some imprecisions inherent to the coarse horizontal resolution (~100 km and simplified bottom-up emission input.

    To identify possible future hot spots of poor air quality, a multi pollutant index (MPI, suited for global model output, has been applied. It appears that East and South Asia and the Middle East represent such hotspots due to very high pollutant concentrations, while a general increase of MPIs is observed in all populated regions in the Northern Hemisphere. In East Asia a range of pollutant gases and fine particulate matter (PM2.5 is projected to reach very high levels from 2005 onward, while in South Asia air pollution, including ozone, will grow rapidly towards the middle of the century. Around the Persian Gulf, where natural PM2.5 concentrations are already high (desert dust, ozone levels are expected to increase strongly.

    The population weighted MPI (PW-MPI, which combines demographic and pollutant concentration projections, shows that a rapidly increasing number of people worldwide will experience reduced air quality during the first half of the 21st century. Following this business as usual

  17. Human performance breakdowns are rarely accidents: they are usually very poor choices with disastrous results

    International Nuclear Information System (INIS)

    Besco, Robert O.

    2004-01-01

    When human error is involved in the error chain of accidents in complex systems, the causes of the errors are very seldom the result of: - a random slip,; - one inadvertent oversight,; - a single unintended action,; - one mis-perceived event,; - simple mal-performance of a complex action, or; - a poor training program for the human operators. Invariably, the cause of the break down is in a very poor conscious choice by someone from the operator back through system designer, the supervision, management and leadership through the entire organization. Usually the operator bears the burden of the blame and is either rebuked, retrained or replaced. In systems such as commercial aviation, complex manufacturing systems, power plants, process control systems, information-processing systems and communications networks, the replacement or retraining of individuals or even classes of individuals usually does not result in any long-term improvement of the safety or effectiveness of the system. What is needed is a system that identifies the reasons why the operators made the errors. Further a system is needed that can recommend what can be done to improve the future performance within the system. The professional performance analysis system (PPAS) has been developed and applied to more than 50 major aircraft accidents in the past 30 years. The PPAS is a direct outgrowth of the human performance analysis system developed by Robert Mager over 45 years ago. The PPAS system is applied after a complete and unbiased definition and description of the events of the accident or incident has been developed by the teams of accident investigation and accident reconstruction professionals. The PPAS then uses a systematic protocol and algorithm to determine the reasons as to why the humans committed the errors or why they performed at subnormal performance levels. This process is based on quantitative behavioral science principles and findings that have been demonstrated valid for many

  18. Implementation of the Tobacco Tactics intervention versus usual care in Trinity Health community hospitals

    Directory of Open Access Journals (Sweden)

    Sonia A. Duffy

    2016-11-01

    Full Text Available Abstract Background Guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM implementation framework, a National Institutes of Health-sponsored study compared the nurse-administered Tobacco Tactics intervention to usual care. A prior paper describes the effectiveness of the Tobacco Tactics intervention. This subsequent paper provides data describing the remaining constructs of the RE-AIM framework. Methods This pragmatic study used a mixed methods, quasi-experimental design in five Michigan community hospitals of which three received the nurse-administered Tobacco Tactics intervention and two received usual care. Nurses and patients were surveyed pre- and post-intervention. Measures included reach (patient participation rates, characteristics, and receipt of services, adoption (nurse participation rates and characteristics, implementation (pre-to post-training changes in nurses' attitudes, delivery of services, barriers to implementation, opinions about training, documentation of services, and numbers of volunteer follow-up phone calls, and maintenance (continuation of the intervention once the study ended. Results Reach: Patient participation rates were 71.5 %. Compared to no change in the control sites, there were significant pre- to post-intervention increases in self-reported receipt of print materials in the intervention hospitals (n = 1370, p < 0.001. Adoption: In the intervention hospitals, all targeted units and several non-targeted units participated; 76.0 % (n = 1028 of targeted nurses and 317 additional staff participated in the training, and 92.4 % were extremely or somewhat satisfied with the training. Implementation: Nurses in the intervention hospitals reported increases in providing advice to quit, counseling, medications, handouts, and DVD (all p < 0.05 and reported decreased barriers to implementing smoking cessation services (p < 0.001. Qualitative comments were very

  19. Effect of usual lead apron in decreasing dose rate in nuclear medicine department

    Energy Technology Data Exchange (ETDEWEB)

    Momennezhad, M.; Ghazikhanloo, K.; Zakavi, S.R. [Mashhad Univ. of Medical Sciences (Iran, Islamic Republic of)

    2006-07-01

    Full text of publication follows: Introduction: In a busy nuclear medicine department personnel exposure to radiation is inevitable during patient positioning and radiotracer preparation. There is controversy regarding usage of usual lead aprons with respect to penetrating gamma rays used in nuclear medicine departments as well as production of characteristic lead x-ray from aprons.This study tries to evaluate the effect of 0.5 mm lead apron on dose reduction. Methods and materials: We used three point sources usual radioisotopes used in nuclear medicine departments (99 mTc, 201 Tl and 131 I) and a single head L.F.O.V. gamma camera (S.M.V., D.S.X.) was used for counting purposes. The count rate for each source was about 20 K count/sec in air and in a brain water phantom. All point sources were placed at a distance of 3 meters, parallel to the center of the detector. The collimator was removed and imaging was performed for 1 min with and without lead apron on the detector. Lead apron covered all field of view of the detector. Each imaging was repeated 3 times and mean count was obtained for each radioisotope. The measurements were accomplished from full spectrum and specific region of spectrum such as characteristic lead x rays region (88 keV 20%) with and without apron. Result and Discussion: The measurement and comparison of count rates (count/min) for each source in different conditions (with and without apron source in air and in water phantom) showed that count rates were reduced in air about 77.3%, 84.2% and 40.8% for 99 mTc, 201 Tl and 131 I respectively. The reduction in count rates when sources placed in brain water phantom were 83.5%, 87% and 53.7% for the same isotope respectively. As the main source of radiation for personnel is from scattered photon and with respect to about 83% of count rate reduction using lead aprons for 99 mTc, it is expected that wearing lead apron significantly decrease dose rate. Conclusion: Our study showed that lead aprons

  20. Effect of usual lead apron in decreasing dose rate in nuclear medicine department

    International Nuclear Information System (INIS)

    Momennezhad, M.; Ghazikhanloo, K.; Zakavi, S.R.

    2006-01-01

    Full text of publication follows: Introduction: In a busy nuclear medicine department personnel exposure to radiation is inevitable during patient positioning and radiotracer preparation. There is controversy regarding usage of usual lead aprons with respect to penetrating gamma rays used in nuclear medicine departments as well as production of characteristic lead x-ray from aprons.This study tries to evaluate the effect of 0.5 mm lead apron on dose reduction. Methods and materials: We used three point sources usual radioisotopes used in nuclear medicine departments (99 mTc, 201 Tl and 131 I) and a single head L.F.O.V. gamma camera (S.M.V., D.S.X.) was used for counting purposes. The count rate for each source was about 20 K count/sec in air and in a brain water phantom. All point sources were placed at a distance of 3 meters, parallel to the center of the detector. The collimator was removed and imaging was performed for 1 min with and without lead apron on the detector. Lead apron covered all field of view of the detector. Each imaging was repeated 3 times and mean count was obtained for each radioisotope. The measurements were accomplished from full spectrum and specific region of spectrum such as characteristic lead x rays region (88 keV 20%) with and without apron. Result and Discussion: The measurement and comparison of count rates (count/min) for each source in different conditions (with and without apron source in air and in water phantom) showed that count rates were reduced in air about 77.3%, 84.2% and 40.8% for 99 mTc, 201 Tl and 131 I respectively. The reduction in count rates when sources placed in brain water phantom were 83.5%, 87% and 53.7% for the same isotope respectively. As the main source of radiation for personnel is from scattered photon and with respect to about 83% of count rate reduction using lead aprons for 99 mTc, it is expected that wearing lead apron significantly decrease dose rate. Conclusion: Our study showed that lead aprons

  1. Integrating a Smartphone-Based Self-Management System into Usual Care of Advanced CKD.

    Science.gov (United States)

    Ong, Stephanie W; Jassal, Sarbjit V; Miller, Judith A; Porter, Eveline C; Cafazzo, Joseph A; Seto, Emily; Thorpe, Kevin E; Logan, Alexander G

    2016-06-06

    Patient self-management has been shown to improve health outcomes. We developed a smartphone-based system to boost self-care by patients with CKD and integrated its use into usual CKD care. We determined its acceptability and examined changes in several clinical parameters. We recruited patients with stage 4 or 5 CKD attending outpatient renal clinics who responded to a general information newsletter about this 6-month proof-of-principle study. The smartphone application targeted four behavioral elements: monitoring BP, medication management, symptom assessment, and tracking laboratory results. Prebuilt customizable algorithms provided real-time personalized patient feedback and alerts to providers when predefined treatment thresholds were crossed or critical changes occurred. Those who died or started RRT within the first 2 months were replaced. Only participants followed for 6 months after recruitment were included in assessing changes in clinical measures. In total, 47 patients (26 men; mean age =59 years old; 33% were ≥65 years old) were enrolled; 60% had never used a smartphone. User adherence was high (>80% performed ≥80% of recommended assessments) and sustained. The mean reductions in home BP readings between baseline and exit were statistically significant (systolic BP, -3.4 mmHg; 95% confidence interval, -5.0 to -1.8 and diastolic BP, -2.1 mmHg; 95% confidence interval, -2.9 to -1.2); 27% with normal clinic BP readings had newly identified masked hypertension. One hundred twenty-seven medication discrepancies were identified; 59% were medication errors that required an intervention to prevent harm. In exit interviews, patients indicated feeling more confident and in control of their condition; clinicians perceived patients to be better informed and more engaged. Integrating a smartphone-based self-management system into usual care of patients with advanced CKD proved feasible and acceptable, and it appeared to be clinically useful. The results provide

  2. Pathologies of the uterine endometrial cavity: usual and unusual manifestations and pitfalls on magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Mayumi; Matsuzaki, Kenji; Yoshida, Shusaku; Nishitani, Hiromu [University of Tokushima, Department of Radiology, Tokushima (Japan); Uehara, Hisanori [University of Tokushima, Department of Molecular and Environmental Pathology, Tokushima (Japan); Shimazu, Hideki [Oe Kyoudo Hospital, Department of Radiology (Japan)

    2005-11-01

    The endometrial cavity may demonstrate various imaging manifestations such as normal, reactive, inflammatory, and benign and malignant neoplasms. We evaluated usual and unusual magnetic resonance imaging (MRI) findings of the uterine endometrial cavity, and described the diagnostic clues to differential diagnoses. Surgically proven pathologies of the uterine endometrial cavity were evaluated retrospectively with pathologic correlation. The pathologies included benign endometrial neoplasms such as endometrial hyperplasia and polyp, malignant endometrial neoplasms such as endometrial carcinoma and carcinosarcoma, endometrial-myometrial neoplasm such as endometrial stromal sarcoma, pregnancy-related lesions in the endometrial cavity such as gestational trophoblastic diseases (hydatidiform mole, invasive mole and choriocarcinoma) and placental polyp, myometrial lesions simulating endometrial lesions such as submucosal leiomyoma and some adenomyosis, endometrial neoplasms simulating myometrial lesions such as adenomyomatous polyp and endometrial lesions arising in the hemicavity of a septate/bicornate uterus, and fluid collections in the uterine cavity (hydro/hemato/pyometra). It is important to recognize various imaging findings in these diseases, in order to make a correct preoperative diagnosis. (orig.)

  3. Usual water-related behaviour and 'near-drowning' incidents in young adults.

    Science.gov (United States)

    Gulliver, Pauline; Begg, Dorothy

    2005-06-01

    To describe usual water-related behaviour and 'near-drowning' incidents in a cohort of young New Zealand adults. This was a cross-sectional study based on data collected as part of the Dunedin Multidisciplinary Health and Development Study, which is the study of a cohort (n = 1,037) born between 1 April 1972 and 31 March 1973 in Dunedin, New Zealand. The data analysed were collected at age 21 (1993/94). Each study member was given a face-to-face interview using a structured questionnaire. Males reported a higher level of water confidence, exposure to risk behaviours, and exposure to unsafe locations, and more 'near-drowning' incidents, than the females, but protective behaviour did not differ. Males and females who were 'confident' in the water were more likely to be exposed to unsafe water locations, and water-confident males were more likely to drink alcohol before water activities, but not boating. A total of 169 'near-drowning' incidents were reported by 141 study members (63% males). 'Near-drowning' incidents were associated with unsafe swimming environments for males (p near-drowning' incidents among a high-risk age group. Larger case-control studies are required to further investigate risk factors for 'near-drowning'. IMPLICATIONS FOR PRACTITIONERS: Further investigation is required to determine the effectiveness of providing water skills acquisition in both safe and unsafe environments on 'near-drowning' experience.

  4. A medical home versus temporary housing: the importance of a stable usual source of care.

    Science.gov (United States)

    DeVoe, Jennifer E; Saultz, John W; Krois, Lisa; Tillotson, Carrie J

    2009-11-01

    Little is known about how the stability of a usual source of care (USC) affects access to care. We examined the prevalence of USC changes among low-income children and how these changes were associated with unmet health care need. We conducted a cross-sectional survey of Oregon's food stamp program in 2005. We analyzed primary data from 2681 surveys and then weighted results to 84087 families, adjusting for oversampling and nonresponse. We then ascertained the percentage of children in the Oregon population who had ever changed a USC for insurance reasons, which characteristics were associated with USC change, and how USC change was associated with unmet need. We also conducted a posthoc analysis of data from the Medical Expenditure Panel Survey to confirm similarities between the Oregon sample and a comparable national sample. Children without a USC in the Oregon population had greater odds of reporting an unmet health care need than those with a USC. This pattern was similar in national estimates. Among the Oregon sample, 23% had changed their USC because of insurance reasons, and 10% had no current USC. Compared with children with a stable USC, children who had changed their USC had greater odds of reporting unmet medical need, unmet prescription need, delayed care, unmet dental need, and unmet counseling need. This study highlights the importance of ensuring stability with a USC. Moving low-income children into new medical homes could disturb existing USC relationships, thereby merely creating "temporary housing."

  5. European Gas in the Next Century. Fundamental Changes or Business as Usual?

    Energy Technology Data Exchange (ETDEWEB)

    Norvik, Harald [Statoil, Stavanger (Norway)

    1999-07-01

    The oil price development is surprising. As soon as a consensus has been formed, it moves in some direction opposite of what was expected. Producers should be prepared to meet a future with declining rather than increasing prices in real terms. In this presentation, the President and Chief Executive Officer of Statoil focuses on some aspects he believes to be important for the evolution of current and future natural gas trade: Demand, supply and prices, Innovation, Geopolitical environment. The European gas industry is moving into the next century after a remarkable development with extensive infrastructure and solid trade patterns established. The future will bring new challenges. The market will be more transparent and more competitive. Cost efficiency and capacity utilization of existing infrastructure will be key factors in order to exploit production at competitive costs. Big reserves are available, although at more remote locations which call for strong commercial players and strong relations between the producers and the distributors if new big supply projects shall be lifted. Norway has gained a competitive position, but new measures will be needed in order to ensure a competitive position for the commercial companies also in the future. The shape of the gas business has developed continuously and market changes will keep it doing so. Therefore, Business as usual will never be a winning strategy in a world of change.

  6. P63 marker Expression in Usual Skin Cancers Compared With Non Tumoral Skin Lesions

    Directory of Open Access Journals (Sweden)

    Abdolhamid Esmaili

    2017-07-01

    Full Text Available Background: Non-melanoma skin cancers including basal cell carcinoma and squamous cell carcinoma are the most common cancers in human. The aim of this study was to determine the expression of P63 marker in usual skin cancers compared with non-tomoral skin lesions. Materials and Methods: In this cross-sectional study, sampling was performed from archival blocks of Shahid Mohammadi hospital patients during 2010-2011. 60 samples (including 30 samples of non tumoral skin lesions and 30 samples of basal cell carcinoma and squamous cell carcinoma were studied and evaluation of p63 gene expression was done with Immunohistochemistry method. T-test and Chi-square were used for analysis of data. Results: P63 gene were expressed in 4 cases (13.33 % of non tumoral lesions and all tumoral lesions (100 %. In tumoral lesions, 5 cases (16.66 % showed 1+ severity experssion, 11 cases (36.66% 2 + severity experssion and 14 cases (46.66 % 3+severity experssion. All 4 non tumoral lesions shoed 1+ severity experssion of P63gene. Conclusion: The results of this study indicated that the incidence and severity of gene expression of P63 can be use for differentiation between basal cell carcinoma and squamous cell carcinoma as well as non-tumoral skin lesions. 

  7. European Gas in the Next Century. Fundamental Changes or Business as Usual?

    International Nuclear Information System (INIS)

    Norvik, Harald

    1999-01-01

    The oil price development is surprising. As soon as a consensus has been formed, it moves in some direction opposite of what was expected. Producers should be prepared to meet a future with declining rather than increasing prices in real terms. In this presentation, the President and Chief Executive Officer of Statoil focuses on some aspects he believes to be important for the evolution of current and future natural gas trade: Demand, supply and prices, Innovation, Geopolitical environment. The European gas industry is moving into the next century after a remarkable development with extensive infrastructure and solid trade patterns established. The future will bring new challenges. The market will be more transparent and more competitive. Cost efficiency and capacity utilization of existing infrastructure will be key factors in order to exploit production at competitive costs. Big reserves are available, although at more remote locations which call for strong commercial players and strong relations between the producers and the distributors if new big supply projects shall be lifted. Norway has gained a competitive position, but new measures will be needed in order to ensure a competitive position for the commercial companies also in the future. The shape of the gas business has developed continuously and market changes will keep it doing so. Therefore, Business as usual will never be a winning strategy in a world of change

  8. The potential of telehealth for 'business as usual' in outpatient clinics.

    Science.gov (United States)

    Day, Karen; Kerr, Patricia

    2012-04-01

    A six-month pilot study was conducted to ascertain the value of using high-definition videoconferencing equipment in an outpatients' setting. The videoconferencing equipment, which included digital biometric equipment, was installed in the outpatient clinics of a remote health service in New Zealand. Use of the equipment was evaluated using action research techniques. Clinicians were interviewed about their assessment of the equipment's usefulness. Patients and their carers completed questionnaires about their clinic experience. During the pilot trial, 109 patients were seen in 25 clinics of six different specialities. Questionnaire results showed that patients and their companions had a good user experience, similar to a face-to-face appointment. Clinicians found that the large screen, sense of proximity, video clarity and definition, and lack of sound/picture lag worked well for certain types of outpatients' clinics, e.g. methadone maintenance clinics. The need for process changes made it difficult to turn telehealth into business as usual in an environment built for face-to-face appointments. We conclude that videoconference equipment has potential to become integral to outpatients' clinics.

  9. Correlation of pulmonary function and usual interstitial pneumonia computed tomography patterns in idiopathic pulmonary fibrosis.

    Science.gov (United States)

    Arcadu, Antonella; Byrne, Suzanne C; Pirina, Pietro; Hartman, Thomas E; Bartholmai, Brian J; Moua, Teng

    2017-08-01

    Little is known about presenting 'inconsistent' or 'possible' usual interstitial pneumonia (UIP) computed tomography (CT) patterns advancing to 'consistent' UIP as disease progresses in idiopathic pulmonary fibrosis (IPF). We hypothesized that if 'consistent' UIP represented more advanced disease, such a pattern on presentation should also correlate with more severe pulmonary function test (PFT) abnormalities. Consecutive IPF patients (2005-2013) diagnosed by international criteria with baseline PFT and CT were included. Presenting CTs were assessed by three expert radiologists for consensus UIP pattern ('consistent', 'possible', and 'inconsistent'). Approximation of individual and combined interstitial abnormalities was also performed with correlation of interstitial abnormalities and UIP CT pattern made with PFT findings and survival. Three-hundred and fifty patients (70% male) were included with a mean age of 68.3 years. Mean percent predicted forced vital capacity (FVC%) and diffusion capacity (DLCO%) was 64% and 45.5% respectively. Older age and male gender correlated more with 'consistent' UIP CT pattern. FVC% was not associated with any UIP pattern but did correlate with total volume of radiologist assessed interstitial abnormalities. DLCO% was lower in those with 'consistent' UIP pattern. A 'consistent' UIP CT pattern was also not independently predictive of survival after correction for age, gender, FVC%, and DLCO%. PFT findings appear to correlate with extent of radiologic disease but not specific morphologic patterns. Whether such UIP patterns represent different stages of disease severity or radiologic progression is not supported by coinciding pulmonary function decline. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Managing Nature–Business as Usual: Resource Extraction Companies and Their Representations of Natural Landscapes

    Directory of Open Access Journals (Sweden)

    Mark Brown

    2015-11-01

    Full Text Available This article contributes to knowledge of how one category of business organization, very large, British-based, natural resource extraction corporations, has begun to manage its operations for sustainability. The object of study is a large volume of texts that make representations of the managing-for-sustainability practices of these multinational corporations (MNCs. The macro-level textual analysis identifies patterns in the wording of the representations of practice. Hajer’s understanding of discourse, in which ideas are contextualized within social processes of practice, provides the theoretical approach for discourse analysis that gives an insight into how they understand and practice sustainability. Through this large-scale discourse analysis, illustrated in the article with specific textual examples, one can see that these natural resource MNCs are developing a vocabulary and a “grammar” which enables them to manage natural spaces in the same way that they are able to manage their own far-flung business operations. They make simplified representations of the much more complex natural landscapes in which their operations are sited and these models of nature can then be incorporated into the corporations’ operational management processes. Their journey towards sustainability delivers, in practice, the management of nature as business continues as usual.

  11. The Impact of Automation on Employment: Just the Usual Structural Change?

    Directory of Open Access Journals (Sweden)

    Ben Vermeulen

    2018-05-01

    Full Text Available We study the projected impact of automation on employment in the forthcoming decade, both at the macro-level and in actual (types of sectors. Hereto, we unite an evolutionary economic model of multisectoral structural change with labor economic theory. We thus get a comprehensive framework of how displacement of labor in sectors of application is compensated by intra- and intersectoral countervailing effects and notably mopped up by newly created, labor-intensive sectors. We use several reputable datasets with expert projections on employment in occupations affected by automation (and notably by the introduction of robotics and AI to pinpoint which and how sectors and occupations face employment shifts. This reveals how potential job loss due to automation in “applying” sectors is counterbalanced by job creation in “making” sectors as well in complementary and quaternary, spillover sectors. Finally, we study several macro-level scenarios on employment and find that mankind is facing “the usual structural change” rather than the “end of work”. We provide recommendations on policy instruments that enhance the dynamic efficiency of structural change.

  12. Parent and child usual source of care and children's receipt of health care services.

    Science.gov (United States)

    DeVoe, Jennifer E; Tillotson, Carrie J; Wallace, Lorraine S; Angier, Heather; Carlson, Matthew J; Gold, Rachel

    2011-01-01

    PURPOSE In the United States, children who have a usual source of care (USC) have better access to health care than those who do not, but little is known about how parental USC affects children's access. We examined the association between child and parent USC patterns and children's access to health care services. METHODS We undertook a secondary analysis of nationally representative, cross-sectional data from children participating in the 2002-2007 Medical Expenditure Panel Survey (n = 56,302). We assessed 10 outcome measures: insurance coverage gaps, no doctor visits in the past year, less than yearly dental visits, unmet medical and prescription needs, delayed care, problems getting care, and unmet preventive counseling needs regarding healthy eating, regular exercise, car safety devices, and bicycle helmets. RESULTS Among children, 78.6% had a USC and at least 1 parent with a USC, whereas 12.4% had a USC but no parent USC. Children with a USC but no parent USC had a higher likelihood of several unmet needs, including an insurance coverage gap (adjusted risk ratio [aRR] 1.33; 95% confidence interval [CI], 1.21-1.47), an unmet medical or prescription need (aRR 1.70; 95% CI 1.09-2.65), and no yearly dental visits (aRR 1.12; 95% CI 1.06-1.18), compared with children with a USC whose parent(s) had a USC. CONCLUSIONS Among children with a USC, having no parent USC was associated with a higher likelihood of reporting unmet needs when compared with children whose parent(s) had a USC. Policy reforms should ensure access to a USC for all family members.

  13. Enterovirus 71-related encephalomyelitis: usual and unusual magnetic resonance imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Seonah; Suh, Sang-Il; Ha, Su Min; Seol, Hae-Young [Korea University Guro Hospital, Korea University College of Medicine, Department of Radiology, Seoul (Korea, Republic of); Byeon, Jung Hye; Eun, Baik-Lin [Korea University Guro Hospital, Korea University College of Medicine, Department of Pediatrics, Seoul (Korea, Republic of); Lee, Young Hen; Seo, Hyung Suk [Korea University Ansan Hospital, Korea University College of Medicine, Department of Radiology, Ansan (Korea, Republic of); Eun, So-Hee [Korea University Ansan Hospital, Korea University College of Medicine, Department of Pediatrics, Ansan (Korea, Republic of)

    2012-03-15

    Most enterovirus (EV) 71 infections manifest as mild cases of hand-foot-mouth disease (HFMD)/herpangina with seasonal variations, having peak incidence during the summer. Meanwhile, EV 71 may involve the central nervous system (CNS), causing severe neurologic disease. In many cases, enteroviral encephalomyelitis involves the central midbrain, posterior portion of the medulla oblongata and pons, bilateral dentate nuclei of the cerebellum, and the ventral roots of the cervical spinal cord, and the lesions show hyperintensity on T2-weighted and fluid-attenuation inversion recovery (FLAIR) images. Our goal was to review usual and unusual magnetic resonance (MR) findings in CNS involvement of enteroviral infection. Among consecutive patients who had HFMD and clinically suspected encephalitis or myelitis and who underwent brain or spinal MR imaging, five patients revealed abnormal MR findings. Diffusion-weighted and conventional MR and follow-up MR images were obtained. From cerebrospinal fluid, stool, or nasopharyngeal swabs, EV 71 was confirmed in all patients. MR imaging studies of two patients showed hyperintensity in the posterior portion of the brainstem on T2-weighted and FLAIR images, which is the well-known MR finding of EV 71 encephalitis. The remaining three cases revealed unusual manifestations: leptomeningeal enhancement, abnormal enhancement along the ventral roots at the conus medullaris level without brain involvement, and hyperintensity in the left hippocampus on T2/FLAIR images. EV 71 encephalomyelitis shows relatively characteristic MR findings; therefore, imaging can be helpful in radiologic diagnosis. However, physicians should also be aware of unusual radiologic manifestations of EV 71. (orig.)

  14. Variations in area-level disadvantage of Australian registered fitness trainers usual training locations

    Directory of Open Access Journals (Sweden)

    Jason A. Bennie

    2016-07-01

    Full Text Available Abstract Background Leisure-time physical activity and strength training participation levels are low and socioeconomically distributed. Fitness trainers (e.g. gym/group instructors may have a role in increasing these participation levels. However, it is not known whether the training location and characteristics of Australian fitness trainers vary between areas that differ in socioeconomic status. Methods In 2014, a sample of 1,189 Australian trainers completed an online survey with questions about personal and fitness industry-related characteristics (e.g. qualifications, setting, and experience and postcode of their usual training location. The Australian Bureau of Statistics ‘Index of Relative Socioeconomic Disadvantage’ (IRSD was matched to training location and used to assess where fitness professionals trained and whether their experience, qualification level and delivery methods differed by area-level disadvantage. Linear regression analysis was used to examine the relationship between IRSD score and selected characteristics adjusting for covariates (e.g. sex, age. Results Overall, 47 % of respondents worked in areas within the three least-disadvantaged deciles. In contrast, only 14.8 % worked in the three most-disadvantaged deciles. In adjusted regression models, fitness industry qualification was positively associated with a higher IRSD score (i.e. working in the least-disadvantaged areas (Cert III: ref; Cert IV β:13.44 [95 % CI 3.86-23.02]; Diploma β:15.77 [95 % CI: 2.17-29.37]; Undergraduate β:23.14 [95 % CI: 9.41-36.86]. Conclusions Fewer Australian fitness trainers work in areas with high levels of socioeconomic disadvantaged areas than in areas with low levels of disadvantage. A higher level of fitness industry qualifications was associated with working in areas with lower levels of disadvantage. Future research should explore the effectiveness of providing incentives that encourage more fitness trainers and those with

  15. Variations in area-level disadvantage of Australian registered fitness trainers usual training locations.

    Science.gov (United States)

    Bennie, Jason A; Thornton, Lukar E; van Uffelen, Jannique G Z; Banting, Lauren K; Biddle, Stuart J H

    2016-07-11

    Leisure-time physical activity and strength training participation levels are low and socioeconomically distributed. Fitness trainers (e.g. gym/group instructors) may have a role in increasing these participation levels. However, it is not known whether the training location and characteristics of Australian fitness trainers vary between areas that differ in socioeconomic status. In 2014, a sample of 1,189 Australian trainers completed an online survey with questions about personal and fitness industry-related characteristics (e.g. qualifications, setting, and experience) and postcode of their usual training location. The Australian Bureau of Statistics 'Index of Relative Socioeconomic Disadvantage' (IRSD) was matched to training location and used to assess where fitness professionals trained and whether their experience, qualification level and delivery methods differed by area-level disadvantage. Linear regression analysis was used to examine the relationship between IRSD score and selected characteristics adjusting for covariates (e.g. sex, age). Overall, 47 % of respondents worked in areas within the three least-disadvantaged deciles. In contrast, only 14.8 % worked in the three most-disadvantaged deciles. In adjusted regression models, fitness industry qualification was positively associated with a higher IRSD score (i.e. working in the least-disadvantaged areas) (Cert III: ref; Cert IV β:13.44 [95 % CI 3.86-23.02]; Diploma β:15.77 [95 % CI: 2.17-29.37]; Undergraduate β:23.14 [95 % CI: 9.41-36.86]). Fewer Australian fitness trainers work in areas with high levels of socioeconomic disadvantaged areas than in areas with low levels of disadvantage. A higher level of fitness industry qualifications was associated with working in areas with lower levels of disadvantage. Future research should explore the effectiveness of providing incentives that encourage more fitness trainers and those with higher qualifications to work in more socioeconomically

  16. Diagnostic accuracy of computed tomography and histopathology in the diagnosis of usual interstitial pneumonia

    International Nuclear Information System (INIS)

    Aaloekken, Trond Mogens; Mynarek, Georg; Kolbenstvedt, Alf; Naalsund, Anne; Elnaes Berstad, Audun; Solberg, Steinar; Stroem, Erik H.; Scott, Helge; Soeyseth, Vidar

    2012-01-01

    Background: The relative clinical benefit of histopathology and computed tomography (CT) in patients with idiopathic interstitial pneumonia (IIP) is under debate. Purpose: To analyze thin-section CT features and histopathologic findings in patients with usual interstitial pneumonia (UIP) in the clinical context of idiopathic pulmonary fibrosis (IPF), and to evaluate and compare diagnostic accuracy of the two methods among patients with an appropriate spectrum of IIP. Material and Methods: The study included 91 patients (49 men; mean age 53.2 years; median follow-up 7.2 years) with clinically suspected interstitial lung disease. All underwent surgical lung biopsy and thin-section CT. Two independent readers retrospectively assessed the CT images for the extent and pattern of abnormality and made a first-choice diagnosis. Two pathologists retrospectively assessed the histopathologic slides. In 64 patients with IIP, a retrospective composite reference standard identified 41 patients with UIP. CT characteristics of UIP and IIPs other than UIP were compared with univariate and multivariate analyses. Results: There was good agreement between the readers for the correct first-choice CT diagnosis of UIP (κ = 0.79). The sensitivity, specificity, and positive predictive value of the CT diagnosis of UIP were 63%, 96%, and 96%, respectively. The sensitivity, specificity, and positive predictive value of the histological diagnosis of UIP were 73%, 74%, and 83%, respectively. The CT feature that best differentiated UIP from IIPs other than UIP was the extent of reticular pattern (odds ratio, 5.1). Conclusion: Surgical lung biopsy may not be warranted in patients with thin-section CT diagnosis of UIP

  17. Enterovirus 71-related encephalomyelitis: usual and unusual magnetic resonance imaging findings

    International Nuclear Information System (INIS)

    Jang, Seonah; Suh, Sang-Il; Ha, Su Min; Seol, Hae-Young; Byeon, Jung Hye; Eun, Baik-Lin; Lee, Young Hen; Seo, Hyung Suk; Eun, So-Hee

    2012-01-01

    Most enterovirus (EV) 71 infections manifest as mild cases of hand-foot-mouth disease (HFMD)/herpangina with seasonal variations, having peak incidence during the summer. Meanwhile, EV 71 may involve the central nervous system (CNS), causing severe neurologic disease. In many cases, enteroviral encephalomyelitis involves the central midbrain, posterior portion of the medulla oblongata and pons, bilateral dentate nuclei of the cerebellum, and the ventral roots of the cervical spinal cord, and the lesions show hyperintensity on T2-weighted and fluid-attenuation inversion recovery (FLAIR) images. Our goal was to review usual and unusual magnetic resonance (MR) findings in CNS involvement of enteroviral infection. Among consecutive patients who had HFMD and clinically suspected encephalitis or myelitis and who underwent brain or spinal MR imaging, five patients revealed abnormal MR findings. Diffusion-weighted and conventional MR and follow-up MR images were obtained. From cerebrospinal fluid, stool, or nasopharyngeal swabs, EV 71 was confirmed in all patients. MR imaging studies of two patients showed hyperintensity in the posterior portion of the brainstem on T2-weighted and FLAIR images, which is the well-known MR finding of EV 71 encephalitis. The remaining three cases revealed unusual manifestations: leptomeningeal enhancement, abnormal enhancement along the ventral roots at the conus medullaris level without brain involvement, and hyperintensity in the left hippocampus on T2/FLAIR images. EV 71 encephalomyelitis shows relatively characteristic MR findings; therefore, imaging can be helpful in radiologic diagnosis. However, physicians should also be aware of unusual radiologic manifestations of EV 71. (orig.)

  18. Neuronal and microglial regulators of cortical wiring: usual and novel guideposts

    Directory of Open Access Journals (Sweden)

    Paola eSquarzoni

    2015-07-01

    Full Text Available Neocortex functioning relies on the formation of complex networks that begins to be assembled during embryogenesis by highly stereotyped processes of cell migration and axonal navigation. The guidance of cells and axons is driven by extracellular cues, released along by final targets or intermediate targets located along specific pathways. In particular, guidepost cells, originally described in the grasshopper, are considered discrete, specialized cell populations located at crucial decision points along axonal trajectories that regulate tract formation. These cells are usually early-born, transient and act at short-range or via cell-cell contact. The vast majority of guidepost cells initially identified were glial cells, which play a role in the formation of important axonal tracts in the forebrain, such as the corpus callosum, anterior and post-optic commissures as well as optic chiasm. In the last decades, tangential migrating neurons have also been found to participate in the guidance of principal axonal tracts in the forebrain. This is the case for several examples such as guideposts for the lateral olfactory tract (LOT, corridor cells, which open an internal path for thalamo-cortical axons and Cajal-Retzius cells that have been involved in the formation of the entorhino-hippocampal connections. More recently, microglia, the resident macrophages of the brain, were specifically observed at the crossroads of important neuronal migratory routes and axonal tract pathways during forebrain development. We furthermore found that microglia participate to the shaping of prenatal forebrain circuits, thereby opening novel perspectives on forebrain development and wiring. Here we will review the last findings on already known guidepost cells populations and will discuss the role of microglia as a potentially new class of atypical guidepost cells.

  19. Diagnostic accuracy of computed tomography and histopathology in the diagnosis of usual interstitial pneumonia

    Energy Technology Data Exchange (ETDEWEB)

    Aaloekken, Trond Mogens; Mynarek, Georg; Kolbenstvedt, Alf (Dept. of Radiology, Oslo Univ. Hospital Rikshospitalet, Oslo (Norway)), Email: trond.mogens.aalokken@rikshospitalet.no; Naalsund, Anne (Dept. of Pulmonology, Oslo Univ. Hospital Rikshospitalet (Norway)); Elnaes Berstad, Audun (Dept. of Radiology, Oslo Univ. Hospital Rikshospitalet, Oslo (Norway); Univ. of Oslo (Norway)); Solberg, Steinar (Dept. of Thoracic Surgery, Oslo Univ. Hospital Rikshospitalet (Norway)); Stroem, Erik H.; Scott, Helge (Dept. of Pathology, Oslo Univ. Hospital Rikshospitalet (Norway)); Soeyseth, Vidar (Univ. of Oslo (Norway); Depts. of Pulmonology, Akershus Univ. Hospital, Loerenskog (Norway))

    2012-04-15

    Background: The relative clinical benefit of histopathology and computed tomography (CT) in patients with idiopathic interstitial pneumonia (IIP) is under debate. Purpose: To analyze thin-section CT features and histopathologic findings in patients with usual interstitial pneumonia (UIP) in the clinical context of idiopathic pulmonary fibrosis (IPF), and to evaluate and compare diagnostic accuracy of the two methods among patients with an appropriate spectrum of IIP. Material and Methods: The study included 91 patients (49 men; mean age 53.2 years; median follow-up 7.2 years) with clinically suspected interstitial lung disease. All underwent surgical lung biopsy and thin-section CT. Two independent readers retrospectively assessed the CT images for the extent and pattern of abnormality and made a first-choice diagnosis. Two pathologists retrospectively assessed the histopathologic slides. In 64 patients with IIP, a retrospective composite reference standard identified 41 patients with UIP. CT characteristics of UIP and IIPs other than UIP were compared with univariate and multivariate analyses. Results: There was good agreement between the readers for the correct first-choice CT diagnosis of UIP (kappa = 0.79). The sensitivity, specificity, and positive predictive value of the CT diagnosis of UIP were 63%, 96%, and 96%, respectively. The sensitivity, specificity, and positive predictive value of the histological diagnosis of UIP were 73%, 74%, and 83%, respectively. The CT feature that best differentiated UIP from IIPs other than UIP was the extent of reticular pattern (odds ratio, 5.1). Conclusion: Surgical lung biopsy may not be warranted in patients with thin-section CT diagnosis of UIP

  20. Fatty Acid and Cholesterol Concentrations in Usually Consumed Fish in Brazil

    Directory of Open Access Journals (Sweden)

    Carlos Scherr

    2015-02-01

    Full Text Available Background: Several studies have demonstrated clinical benefits of fish consumption for the cardiovascular system. These effects are attributed to the increased amounts of polyunsaturated fatty acids in these foods. However, the concentrations of fatty acids may vary according to region. Objective: The goal of this study was to determine the amount of,cholesterol and fatty acids in 10 Brazilian fishes and in a non-native farmed salmon usually consumed in Brazil. Methods: The concentrations of cholesterol and fatty acids, especially omega-3, were determined in grilled fishes. Each fish sample was divided in 3 sub-samples (chops and each one was extracted from the fish to minimize possible differences in muscle and fat contents. Results: The largest cholesterol amount was found in white grouper (107.6 mg/100 g of fish and the smallest in badejo (70 mg/100 g. Omega-3 amount varied from 0.01 g/100 g in badejo to 0.900 g/100 g in weakfish. Saturated fat varied from 0.687 g/100 g in seabass to 4.530 g/100 g in filhote. The salmon had the greatest concentration of polyunsaturated fats (3.29 g/100 g and the highest content of monounsaturated was found in pescadinha (5.98 g/100 g. Whiting and boyfriend had the best omega-6/omega 3 ratios respectively 2.22 and 1.19, however these species showed very little amounts of omega-3. Conclusion: All studied Brazilian fishes and imported salmon have low amounts of saturated fat and most of them also have low amounts of omega-3.

  1. [Spanish collaborative study: Description of usual clinical practice in infant obesity].

    Science.gov (United States)

    Lechuga Sancho, Alfonso; Palomo Atance, Enrique; Rivero Martin, María José; Gil-Campos, Mercedes; Leis Trabazo, Rosaura; Bahíllo Curieses, María Pilar; Bueno Lozano, Gloria

    2018-06-01

    Childhood obesity is a high prevalence health problem. Although there are clinical guidelines for its management, there is variability in its clinical approach. The aim of this study is to describe the usual clinical practice in Paediatric Endocrinology Units in Spain and to evaluate if it resembles the recommended guidelines. An observational, cross-sectional and descriptive study was carried out by means of a questionnaire sent to paediatric endocrinologists of the Spanish Society of Paediatric Endocrinology. The questions were formulated based on the recommendations of "Clinical Practice Guidelines on the Prevention and Treatment of Childhood Obesity" issued by the Spanish Ministry of Health. A total of 125 completed questionnaires were obtained from all Autonomous Communities. Variability was observed both in the number of patients attended and in the frequency of the visits. The majority (70%) of the paediatricians who responded did not have a dietitian, psychologist or psychiatrist, in their centre to share the treatment for obese children. As regards treatment, dietary advice is the most used, and 69% have never prescribed weight-loss drugs. Of those who have prescribed them, 52.6% did not use informed consent as a prior step to them being used. There are few centres that comply with the recommendations of the clinical practice guidelines on prevention and treatment of childhood obesity as an established quality plan. Clinical practice differs widely among the paediatric endocrinologists surveyed. There are no uniform protocols of action, and in general there is limited availability of resources for the multidisciplinary treatment required by this condition. Copyright © 2017 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  2. Usual Primary Care Provider Characteristics of a Patient-Centered Medical Home and Mental Health Service Use.

    Science.gov (United States)

    Jones, Audrey L; Cochran, Susan D; Leibowitz, Arleen; Wells, Kenneth B; Kominski, Gerald; Mays, Vickie M

    2015-12-01

    The benefits of the patient-centered medical home (PCMH) over and above that of a usual source of medical care have yet to be determined, particularly for adults with mental health disorders. To examine qualities of a usual provider that align with PCMH goals of access, comprehensiveness, and patient-centered care, and to determine whether PCMH qualities in a usual provider are associated with the use of mental health services (MHS). Using national data from the Medical Expenditure Panel Survey, we conducted a lagged cross-sectional study of MHS use subsequent to participant reports of psychological distress and usual provider and practice characteristics. A total of 2,358 adults, aged 18-64 years, met the criteria for serious psychological distress and reported on their usual provider and practice characteristics. We defined "usual provider" as a primary care provider/practice, and "PCMH provider" as a usual provider that delivered accessible, comprehensive, patient-centered care as determined by patient self-reporting. The dependent variable, MHS, included self-reported mental health visits to a primary care provider or mental health specialist, counseling, and psychiatric medication treatment over a period of 1 year. Participants with a usual provider were significantly more likely than those with no usual provider to have experienced a primary care mental health visit (marginal effect [ME] = 8.5, 95 % CI = 3.2-13.8) and to have received psychiatric medication (ME = 15.5, 95 % CI = 9.4-21.5). Participants with a PCMH were additionally more likely than those with no usual provider to visit a mental health specialist (ME = 7.6, 95 % CI = 0.7-14.4) and receive mental health counseling (ME = 8.5, 95 % CI = 1.5-15.6). Among those who reported having had any type of mental health visit, participants with a PCMH were more likely to have received mental health counseling than those with only a usual provider (ME = 10.0, 95 % CI

  3. Revisión histórica del sexismo en el cine español. El extraño caso de la película 'Amanece que no es poco'

    Directory of Open Access Journals (Sweden)

    Pedro Vázquez Miraz

    2017-04-01

    Full Text Available Se presenta en esta investigación una revisión sistémica de artículos científicos relacionados con películas españolas que abordan situaciones de violencia hacia las mujeres y/o que tratan a éstas bajo el prisma tradicional de los roles sexuales, permitiendo que esos actos agresivos se enmarquen, de forma exclusiva, en el ámbito doméstico. De forma sorprendente, en todos los artículos y revisiones de películas que se centran en el papel de la mujer y/o de la violencia que ésta sufre, la célebre película de José Luis Cuerda Amanece, que no es poco, ni siquiera es nombrada como simple ejemplo de película española donde la violencia de género es evidente.

  4. Myositis-associated usual interstitial pneumonia has a better survival than idiopathic pulmonary fibrosis.

    Science.gov (United States)

    Aggarwal, Rohit; McBurney, Christine; Schneider, Frank; Yousem, Samuel A; Gibson, Kevin F; Lindell, Kathleen; Fuhrman, Carl R; Oddis, Chester V

    2017-03-01

    To compare the survival outcomes between myositis-associated usual interstitial pneumonia (MA-UIP) and idiopathic pulmonary fibrosis (IPF-UIP). Adult MA-UIP and IPF-UIP patients were identified using CTD and IPF registries. The MA-UIP cohort included myositis or anti-synthetase syndrome patients with interstitial lung disease while manifesting UIP on high-resolution CT chest and/or a lung biopsy revealing UIP histology. IPF subjects met American Thoracic Society criteria and similarly had UIP histopathology. Kaplan-Meier survival curves compared cumulative and pulmonary event-free survival (event = transplant or death) between (i) all MA-UIP and IPF-UIP subjects, (ii) MA-UIP with biopsy proven UIP (n = 25) vs IPF-UIP subjects matched for age, gender and baseline forced vital capacity (±10%). Cox proportional hazards ratios compared the survival controlling for co-variates. Eighty-one IPF-UIP and 43 MA-UIP subjects were identified. The median cumulative and event-free survival time in IPF vs MA-UIP was 5.25/1.8 years vs 16.2/10.8 years, respectively. Cumulative and event-free survival was significantly worse in IPF-UIP vs MA-UIP [hazards ratio of IPF-UIP was 2.9 (95% CI: 1.5, 5.6) and 5.0 (95% CI: 2.8, 8.7) (P < 0.001), respectively]. IPF-UIP event-free survival (but not cumulative) remained significantly worse than MA-UIP with a hazards ratio of 6.4 (95% CI: 3.0, 13.8) after controlling for age at interstitial lung disease diagnosis, gender, ethnicity and baseline forced vital capacity%. Respiratory failure was the most common cause of death in both groups. A sub-analysis of 25 biopsy-proven MA-UIP subjects showed similar results. MA-UIP patients demonstrated a significant survival advantage over a matched IPF cohort, suggesting that despite similar histological and radiographic findings at presentation, the prognosis of MA-UIP is superior to that of IPF-UIP. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Rheumatology

  5. Healthcare utilization in adults with opioid dependence receiving extended release naltrexone compared to treatment as usual.

    Science.gov (United States)

    Soares, William E; Wilson, Donna; Rathlev, Niels; Lee, Joshua D; Gordon, Michael; Nunes, Edward V; O'Brien, Charles P; Friedmann, Peter D

    2018-02-01

    Opioid use disorders have reached epidemic proportions, with overdose now the leading cause of accidental death in the United States. Extended release naltrexone (XR-NTX) has emerged as a medication treatment that reduces opioid use and craving. However, the effect of XR-NTX therapy on acute healthcare utilization, including emergency department visits and inpatient hospitalizations, remains uncertain. The objective of the current study is to evaluate hospital-based healthcare resource utilization in adults involved in the criminal justice system with a history of opioid use disorder randomized to XR-NTX therapy compared with treatment as usual (TAU) during a 6-month treatment phase and 12months post-treatment follow up. This retrospective exploratory analysis uses data collected in a published randomized trial. Comparisons of the number of emergency department visits and hospital admissions (for drug detox, psychiatric care and other medical reasons) were performed using chi square tests for any admission and negative binomial models for number of admissions. Of the 308 participants randomized, 96% had utilization data (76% complete 6months, 67% complete follow up). No significant differences were seen in overall healthcare utilization (IRR=0.88, 95%CI 0.63-1.23, p=0.45), or substance use-related drug detox hospitalizations (IRR=0.83, 95%CI 0.32-2.16, p=0.71). Despite having more participants report chronic medical problems at baseline (43% vs. 32%, p=0.05), those receiving XR-NTX generally experienced equivalent or lower rates of healthcare utilization compared to TAU. The XR-NTX group had significantly lower medical/surgical related hospital admissions (IRR=0.55, 95%CI 0.30-1.00, p=0.05) during the course of the entire study. XR-NTX did not significantly increase rates of healthcare utilization compared to TAU. Provider concerns regarding healthcare utilization should not preclude the consideration of XR-NTX as therapy for opioid use disorders. Copyright © 2018

  6. Moyamoya syndrome as a risk factor for stroke in Saudi children: Novel and usual associations

    International Nuclear Information System (INIS)

    Salih, Mustafa A.; Al-Jarallah, Ahmed A.; Kentab, Amal Y.; Murshid, Waleed R.; Elgamal, Essam A.; Al-Salman, Mussaad M.; Abdel-Gader, Abdel-Galil M.; Alorainy, Ibrahim A.; Hassan, Hamdy H.; Othman, Saleh A.; El-Desouki, Mahmoud I.; Maldergem, L. V.

    2006-01-01

    To report on moyamoya syndrome (MMS) as a risk factor for stroke in a prospective and retrospective cohort of Saudi children. The usual and novel associations of MMS in this cohort will also be described. Children with stroke were evaluated at the Division of Pediatric Neurology at King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia during the periods July 1992 to February 2001 (retrospective study) and February201 to March 2003 (retrospective study). Investigations for suspected cases included hemostatic assays, biochemical, and serological tests. Neuroimaging included CT, MRI, magnetic resonance angiography (MRA), single photon computerized tomography (SPECT) brain scan and conventional cerebral angiography. Moyamoya syndrome was the underlying risk factor for stroke in 6 (5.8%) of the 104 children (aged one month to 12 years). They were 4 females and 2 males. Their first cerebral ischemic event occurred at a mean age of 45 months (median = 44 months, range 17-66 months). In all 6 cases, MMS was associated with an underlying hematologic abnormality or other diseases. Protein C deficiency was identified in one girl and protein S deficiency in another. Two patients had retrospectively, sickle cell disease (SCD) and sickle cell-b-thalassemia (Sb-thalssemia), which had been associated in the latter with membranous ventricular septal defect. Adams-Oliver syndrome (AOS, OMIM 100300) was associated with MMS in an 18-month-old girl. A 4-year-old boy had wrinkly skin syndrome (WWS, OMIM 278250) phenotype. The association of MMS and protein C deficiency was first reported in this cohort of patients, whereas the association of the syndrome with WWS and AOS has not, hitherto, been described. The 3 patients who had MMS associated with protein C deficiency, SCD, and AOS underwent successful revascularization surgery in the form of encephaloduroarteriosynangiosis. Moyamoya syndrome constitutes an important risk factor of

  7. Association of point-of-purchase tobacco advertising and promotions with choice of usual brand among teenage smokers.

    Science.gov (United States)

    Wakefield, Melanie A; Ruel, Erin E; Chaloupka, Frank J; Slater, Sandy J; Kaufman, Nancy J

    2002-01-01

    The objective is to determine the relationship between brand-specific advertising and promotions in convenience stores for Marlboro and Camel cigarettes and choice of usual brand among school students. A cross-sectional survey was designed that merged records of store tobacco advertising and promotions. The survey was administered to 3,890 U.S. high school smokers with a usual brand, matched to 196 convenience stores. Choice of Marlboro as a usual brand was associated with presence of a Marlboro gift with purchase (p purchase promotions (p > .05) and negatively associated with a greater share of exterior advertising voice for Camel (p < .001). The results are consistent with the notion that Marlboro-specific advertising and promotions may influence choice of Marlboro as a usual brand to smoke among teens, but resultsfor Camel are mixed and inconclusive. Further research is required to confirm and extend these findings.

  8. Supplement to “Consolidity: Moving opposite to built-as-usual systems practices”

    Directory of Open Access Journals (Sweden)

    Hassen Taher Dorrah

    2013-12-01

    Full Text Available A new updated conceptual systems change pathway graph for natural and man-made built-as-usual physical systems is developed following a joint two-level event-driven (or activity-driven and time-driven framework. The events and activities “on and above” the normal systems operations are recognized in the form of high influencing level (referred to as the “event-driven or upper system layer(s” acting over the ordinary systems state equations denoted as the “time-driven or the basic system layer(s.” This is envisaged through the existence of some sort of an “Event clocklike register” that runs alongside with the ordinary “time clock”. Different than the ordinary continued operation of the time clock, the event clocklike register begins its operation with the original (or initial system state, steps forward only with the occurrence of any coming event affecting the system, and stops at the final (or end system state. The pathway graph reveals also the important finding that each system (including their parts and components has autonomous self-recording consolidity-based scaled intelligent mechanisms (with infinite stacking of their actions through continuously storing parameters changes internally with the occurrences of their varying environments or events. Conversely, it is envisioned that it is amenable under the existence of the reversibility conditions of the change functions to perform backtracking procedure (reversing direction of event clocklike register at the event-driven or upper system layer(s of the history of affected events through sequentially disclosing the internal overlaid stacking arrangements of systems parameters changes corresponding to such effects. The various stack-based system change classifications and categorizations are also scrutinized. The case study of the change pathway of the stabilized inverted pendulum is provided to thoroughly demonstrate the applicability of the suggested theory. Moreover

  9. End-of-Life Transitions and Hospice Utilization for Adolescents: Does Having a Usual Source of Care Matter?

    Science.gov (United States)

    Keim-Malpass, Jessica; Lindley, Lisa C

    2017-08-01

    Adolescents with life-limiting illnesses have intensive end-of-life trajectories and could benefit from initiation of hospice services. The medical home model, which includes having a usual source of primary care, may help facilitate quality outcomes at the end-of-life for adolescents. The purpose of this study was to determine the relationship between having a usual source of primary care on hospice utilization and end-of-life transitions among adolescents between 15-20 years with a life-limiting illness. A retrospective cohort design used 2007-2010 California Medicaid claims data (n=585). Our dependent variables were hospice utilization (i.e., hospice enrollment, hospice length of stay) and the independent variable was usual source of primary care. Multivariate regression techniques including least squares regression, multivariate logistic regression, and negative binomial regression were used in the analysis of the relationship between usual source of primary care and hospice utilization and end-of-life transitions. Ten percent of our sample utilized hospice services. Having a usual source of primary care was associated with an increase in hospice enrollment, hospice length of stay, and end-of-life transitions. Adolescents with a cancer diagnosis were more likely to enroll in hospice services. For adolescents at the end of life, having a usual source of primary care had a significant impact on hospice enrollment and length of stay. This study is among the first to demonstrate a relationship between primary care and hospice use among this vulnerable population.

  10. Factors associated with different cigarette access behaviours among underage smoking youth who usually smoke contraband (native) cigarettes.

    Science.gov (United States)

    Leatherdale, Scott T; Ahmed, Rashid; Vu, Mary

    2011-01-01

    Given that little is known about how youth access contraband cigarettes, the current study seeks to examine factors associated with how underage smoking youth report usually accessing contraband cigarettes. This study used nationally representative data collected from 41,886 students (grades 9 to 12) as part of the 2006-07 Canadian Youth Smoking Survey (YSS). Using data from current smokers who report that their usual brand of cigarettes is contraband, three logistic regression models were used to examine factors associated with buying cigarettes from a store, getting cigarettes from a family member, or getting cigarettes from friends or strangers. In 2006, 7.9% (n = 1 3,300) of Canadian youth who were current smokers reported that their usual brand of cigarettes was contraband. Among these youth, the majority reported that they usually get their cigarettes from a friend or stranger (54.8%), whereas 26.4% report usually getting them from a family member and 18.8% usually buying their own from a store. Boys were more likely to buy contraband cigarettes from a store, whereas youth with a parent who smokes contraband cigarettes were substantially more likely to get contraband cigarettes from a family member and youth with friends who smoke contraband cigarettes were substantially more likely to get contraband cigarettes from a friend or stranger. Ongoing surveillance of contraband cigarette use among youth and how youth access contraband cigarettes is required for guiding future tobacco control policy and programming activities.

  11. Complicaciones postquirúrgicas, infecciones de la herida luego de la colecistectomía emergente en diabético tipo II. Servicio de emergencia del Hospital General Luis Vernaza, enero 2010 - diciembre 2012.

    OpenAIRE

    Luna Carriel, Tomas David

    2015-01-01

    La colecistectomía es una cirugía frecuente del área de urgencias, se encuentra acompañada de dos comorbilidades usuales como son la diabetes y la obesidad que en nuestro estudio la hemos catalogado de acuerdo a la medida del perímetro de cintura (obesidad abdominal). La colecistectomíaconsiste en la extirpación de la vesícula biliar cuando esta se encuentra con cálculos biliares, pólipos o cualquier otra indicación encontrada por el área decirugía general. En el ámbit...

  12. PROBLEMÁTICAS POCO EXPLORADAS DE LOS JÓVENES EN EL PROCESO DE LA TRANSICIÓN DEMOGRÁFICA. EL CASO DE LA FRONTERA NORTE DE MÉXICO

    Directory of Open Access Journals (Sweden)

    Humberto González Galbán

    2012-12-01

    Full Text Available A pesar de los importantes cuestionamientos que han sido realizados a la “Teoría” de la Transición Demográfica, ésta continúa representando el marco interpretativo más usualmente utilizado por los investigadores de la temática poblacional, los cuales tratan de enriquecerla con lo “observado” en diferentes contextos, buscando las regularidades de las problemáticas poblacionales manifestadas en los mismos con lo acontecido en otras regiones, generalmente de países desarrollados. En tal sentido en el presente artículo se analizan aspectos demográficos o sociales poco explorados, en el marco de dicha teoría, que no obstante, pueden haber tenido un peso importante en la explicación de los cambios poblacionales tales como la  sexualidad y la nupcialidad y asociado a ello el comportamiento reproductivo de las mujeres así como las relaciones de violencia en el marco de la familia y la afectación de todo ello a grupos vulnerables como son los jóvenes. El interés de análisis se centra en los aspectos referidos, considerando como  contexto espacial a los estados limítrofes con los Estados Unidos, en los que los indicadores sociodemográficos sugieren un relativamente avanzado proceso de transición demográfica, lo que pudiera estar vinculado a la influencia norteamericana, escenario que es complejizado por una intensa corriente migratoria desde otras partes del país hacia la región del norte de México.

  13. Motivational, reduction and usual care interventions for smokers who are not ready to quit: a randomized controlled trial.

    Science.gov (United States)

    Klemperer, Elias M; Hughes, John R; Solomon, Laura J; Callas, Peter W; Fingar, James R

    2017-01-01

    To test whether, in comparison to usual care, brief motivational or reduction interventions increase quit attempts (QA) or abstinence among smokers who are not ready to quit. A parallel-group randomized controlled trial of brief motivational (n = 185), reduction (n = 186) or usual care (n = 189) telephone interventions delivered over the course of 4 weeks. Outcomes were assessed at 6- and 12-month follow-ups. No medication was provided. United States. A total of 560 adult smokers of ≥ 10 cigarettes per day who were not ready to quit in the next 30 days. The primary outcomes were whether participants made a QA that lasted ≥ 24 hours and whether they made a QA of any length between baseline and 6 months. Secondary outcomes included 7-day point-prevalence abstinence at 6 and 12 months. The 12-month follow-up was added after the study began. A priori-defined comparisons were between motivational versus usual care and reduction versus usual care conditions. The probability of making a QA that lasted ≥ 24 hours was not significantly different between the motivational (38%) or the reduction (31%) conditions and the usual care (34%) condition [motivational versus usual care odds ratio (OR) = 1.19, 95% confidence interval (CI) = 0.78-1.82; reduction versus usual care OR = 0.89, 95% CI = 0.57-1.36]. Bayes factors ranged from 0.13 to 0.18. Findings regarding a QA of any length were similar. At 6 months, the motivational condition had marginally more abstinence than usual care (11 versus 5%, OR = 2.17, 95% CI = 0.99-4.77), but the reduction condition was not significantly different from usual care (8 versus 5%, OR = 1.57, 95% CI = 0.69-3.59). At 12 months, the motivational condition had significantly more abstinence than usual care (10 versus 4%, OR = 2.80, 95% CI = 1.14-6.88) and the reduction condition had marginally more abstinence than usual care (9 versus 4%, OR = 2.45, 95% CI = 0.98-6.09). Among adult smokers who are not ready

  14. Life changes among homeless persons with mental illness: a longitudinal study of housing first and usual treatment.

    Science.gov (United States)

    Nelson, Geoffrey; Patterson, Michelle; Kirst, Maritt; Macnaughton, Eric; Isaak, Corinne A; Nolin, Danielle; McAll, Christopher; Stergiopoulos, Vicky; Townley, Greg; MacLeod, Timothy; Piat, Myra; Goering, Paula N

    2015-06-01

    This study compared the life changes of homeless people with mental illness participating in Housing First or treatment as usual and examined factors related to various changes. Semistructured narrative interviews were conducted with 219 participants in five Canadian cities at baseline; 197 were interviewed again at 18 months after random assignment to Housing First (N=119) or treatment as usual (N=78). Interviews were coded across 13 life domains, and each participant was categorized as reporting positive, mixed-neutral, or negative changes. Housing First and treatment as usual participants were compared with respect to change patterns. Thematic analysis was used to examine factors related to various changes. The percentage of participants in Housing First reporting positive changes was more than double that for participants in treatment as usual, and treatment as usual participants were four times more likely than Housing First participants to report negative changes. Factors related to positive changes included having stable good-quality housing, increased control over substance use, positive relationships and social support, and valued social roles. Factors related to negative changes included precarious housing, negative social contacts, isolation, heavy substance use, and hopelessness. Factors related to mixed-neutral changes were similar to those for participants reporting negative changes but were less intense. Housing First with intensive support was related to more positive changes among homeless adults with mental illness across five Canadian cities. Those with poor housing or support, more common in treatment as usual, continued to struggle. These findings are relevant for services and social change to benefit this population.

  15. Levonorgestrel-releasing intrauterine system vs. usual medical treatment for menorrhagia: an economic evaluation alongside a randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Sabina Sanghera

    Full Text Available OBJECTIVE: To undertake an economic evaluation alongside the largest randomised controlled trial comparing Levonorgestrel-releasing intrauterine device ('LNG-IUS' and usual medical treatment for women with menorrhagia in primary care; and compare the cost-effectiveness findings using two alternative measures of quality of life. METHODS: 571 women with menorrhagia from 63 UK centres were randomised between February 2005 and July 2009. Women were randomised to having a LNG-IUS fitted, or usual medical treatment, after discussing with their general practitioner their contraceptive needs or desire to avoid hormonal treatment. The treatment was specified prior to randomisation. For the economic evaluation we developed a state transition (Markov model with a 24 month follow-up. The model structure was informed by the trial women's pathway and clinical experts. The economic evaluation adopted a UK National Health Service perspective and was based on an outcome of incremental cost per Quality Adjusted Life Year (QALY estimated using both EQ-5D and SF-6D. RESULTS: Using EQ-5D, LNG-IUS was the most cost-effective treatment for menorrhagia. LNG-IUS costs £100 more than usual medical treatment but generated 0.07 more QALYs. The incremental cost-effectiveness ratio for LNG-IUS compared to usual medical treatment was £1600 per additional QALY. Using SF-6D, usual medical treatment was the most cost-effective treatment. Usual medical treatment was both less costly (£100 and generated 0.002 more QALYs. CONCLUSION: Impact on quality of life is the primary indicator of treatment success in menorrhagia. However, the most cost-effective treatment differs depending on the quality of life measure used to estimate the QALY. Under UK guidelines LNG-IUS would be the recommended treatment for menorrhagia. This study demonstrates that the appropriate valuation of outcomes in menorrhagia is crucial.

  16. How the psychosocial context of clinical trials differs from usual care: A qualitative study of acupuncture patients

    Directory of Open Access Journals (Sweden)

    White Peter

    2011-05-01

    Full Text Available Abstract Background Qualitative studies of participants' experiences in randomised clinical trials (RCTs suggest that the psychosocial context of treatment in RCTs may be quite different to the psychosocial context of treatment in usual practice. This is important, as the psychosocial context of treatment is known to influence patient outcomes in chronic illness. Few studies have directly compared the psychosocial context of treatment across RCTs and usual practice. In this study, we explored differences in psychosocial context between RCT and usual practice settings, using acupuncture as our model. Methods We undertook a secondary analysis of existing qualitative interviews with 54 patients. 27 were drawn from a study of western and traditional acupuncture in usual practice (for a range of painful conditions. 27 were drawn from a qualitative study nested in an RCT of western acupuncture for osteoarthritis of the hip or knee. We used qualitative analysis software to facilitate an inductive thematic analysis in which we identified three main themes. Results In usual practice, starting acupuncture was more likely to be embedded in an active and ongoing search for pain relief, whereas in the RCT starting acupuncture was opportunistic. Usual practice patients reported few uncertainties and these had minimal consequences for them. In the RCT, patients experienced considerable uncertainties about their treatment and its effectiveness, and were particularly concerned about whether they were receiving real (or fake acupuncture. Patients stopped acupuncture only at the end of the fixed course of treatment in the RCT, which was similar to those receiving acupuncture in the public sector National Health Service (NHS. In comparison, private sector patients re-evaluated and re-negotiated treatments particularly when starting to use acupuncture. Conclusions Differences in psychosocial context between RCTs and usual practice could reduce the impact of

  17. Economic evaluation of an intensive group training protocol compared with usual care physiotherapy in patients with chronic low back pain

    NARCIS (Netherlands)

    van der Roer, N.; van Tulder, M.; van Mechelen, W.; de Vet, H.C.W.

    2008-01-01

    STUDY DESIGN. Economic evaluation from a societal perspective conducted alongside a randomized controlled trial with a follow-up of 52 weeks. OBJECTIVE. To evaluate the cost effectiveness and cost utility of an intensive group training protocol compared with usual care physiotherapy in patients with

  18. Brief Strategic Family Therapy versus Treatment as Usual: Results of a Multisite Randomized Trial for Substance Using Adolescents

    Science.gov (United States)

    Robbins, Michael S.; Feaster, Daniel J.; Horigian, Viviana E.; Rohrbaugh, Michael; Shoham, Varda; Bachrach, Ken; Miller, Michael; Burlew, Kathleen A.; Hodgkins, Candy; Carrion, Ibis; Vandermark, Nancy; Schindler, Eric; Werstlein, Robert; Szapocznik, Jose

    2011-01-01

    Objective: To determine the effectiveness of brief strategic family therapy (BSFT; an evidence-based family therapy) compared to treatment as usual (TAU) as provided in community-based adolescent outpatient drug abuse programs. Method: A randomized effectiveness trial in the National Drug Abuse Treatment Clinical Trials Network compared BSFT to…

  19. Effect of lifestyle coaching versus care coordination versus treatment as usual in people with severe mental illness and overweight

    DEFF Research Database (Denmark)

    Jakobsen, Ane Storch; Speyer, Helene; Nørgaard, Hans Christian Brix

    2017-01-01

    as usual group (P = 0.24). Also, there were no intervention effects for any secondary or exploratory outcomes, including cardiorespiratory fitness, weight, physical activity, diet and smoking. No reported adverse events could be ascribed to the intervention. We conclude that there was neither any direct...

  20. Treating Anxiety Disorders in Inner City Schools: Results from a Pilot Randomized Controlled Trial Comparing CBT and Usual Care

    Science.gov (United States)

    Ginsburg, Golda S.; Becker, Kimberly D.; Drazdowski, Tess K.; Tein, Jenn-Yun

    2012-01-01

    Background: The effectiveness of cognitive-behavioral treatment (CBT) in inner city schools, when delivered by novice CBT clinicians, and compared to usual care (UC), is unknown. Objective: This pilot study addressed this issue by comparing a modular CBT for anxiety disorders to UC in a sample of 32 volunteer youth (mean age 10.28 years, 63%…

  1. Effectiveness of Standardized Physiotherapy Exercises for Patients With Difficulty Returning to Usual Activities After Decompression Surgery for Subacromial Impingement Syndrome

    DEFF Research Database (Denmark)

    Christiansen, David Høyrup; Frost, Poul; Falla, Deborah

    2016-01-01

    BACKGROUND: Little is known about the effectiveness of exercise programs after decompression surgery for subacromial impingement syndrome. For patients with difficulty returning to usual activities, special efforts may be needed to improve shoulder function. OBJECTIVE: The purpose of this study w...

  2. Cost-effectiveness of a specialized atrial fibrillation clinic vs. usual care in patients with atrial fibrillation

    NARCIS (Netherlands)

    Hendriks, Jeroen; Tomini, Florian; van Asselt, Thea; Crijns, Harry; Vrijhoef, Hubertus

    AIMS: A recent randomized controlled trial demonstrated significant reductions in cardiovascular hospitalizations and deaths with a nurse-led integrated chronic care approach in patients with atrial fibrillation (AF) compared with usual care. The aim of the present study is to assess

  3. Cost-effectiveness of a specialized atrial fibrillation clinic vs. usual care in patients with atrial fibrillation

    NARCIS (Netherlands)

    Hendriks, J.M.L.; Tomini, F.; van Asselt, A.D.I.; Crijns, H.J.G.M.; Vrijhoef, H.J.M.

    2013-01-01

    Aims A recent randomized controlled trial demonstrated significant reductions in cardiovascular hospitalizations and deaths with a nurse-led integrated chronic care approach in patients with atrial fibrillation (AF) compared with usual care. The aim of the present study is to assess

  4. Disseminated dendriform pulmonary ossification associated with usual interstitial pneumonia: incidence and thin-section CT-pathologic correlation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Sung; Chung, Myung Jin [Sungkyunkwan University School of Medicine, Department of Radiology and Center for Imaging Science, Seoul (Korea); Han, Joungho [Sungkyunkwan University School of Medicine, Department of Pathology, Seoul (Korea); Chung, Man Pyo [Sungkyunkwan University School of Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Seoul (Korea); Choi, Yong Soo [Sungkyunkwan University School of Medicine, Division of Thoracic Surgery, Seoul (Korea)

    2005-08-01

    The aim of this work was to assess the incidence of disseminated pulmonary dendriform ossification in usual interstitial pneumonia and nonspecific interstitial pneumonia, and to correlate thin-section computed tomography (CT) and histopathologic findings. We retrospectively reviewed thin-section CT and pathologic specimens of biopsy-proven usual interstitial pneumonia (75 patients, 57 men and 18 women, mean age 60 years, range 29-83 years) and nonspecific interstitial pneumonia (44 patients, 9 men and 35 women, mean age 55 years, range 20-73 years). On review of CT and histopathologic specimens, diffuse dendriform ossification was identified in five (four men and one woman, age range 41-68 years, mean 58 years) of 75 patients (6.7%) with usual interstitial pneumonia. It was not seen in any of 44 patients with nonspecific interstitial pneumonia. With thin-section CT (osteoporosis window; window width 818, level 273), disseminated dendriform pulmonary ossification was detected as multiple tiny calcifications in bibasilar subpleural lungs (100% sensitive and 100% specific when compared with histopathologic findings as the gold standard). The thin-section CT finding of multiple tiny calcifications in bibasilar subpleural lungs might be of some help in the differential diagnosis between usual interstitial pneumonia and nonspecific interstitial pneumonia, considering they were not seen in any patients with nonspecific interstitial pneumonia (0%, 0/44) in our series. (orig.)

  5. Disseminated dendriform pulmonary ossification associated with usual interstitial pneumonia: incidence and thin-section CT-pathologic correlation

    International Nuclear Information System (INIS)

    Kim, Tae Sung; Chung, Myung Jin; Han, Joungho; Chung, Man Pyo; Choi, Yong Soo

    2005-01-01

    The aim of this work was to assess the incidence of disseminated pulmonary dendriform ossification in usual interstitial pneumonia and nonspecific interstitial pneumonia, and to correlate thin-section computed tomography (CT) and histopathologic findings. We retrospectively reviewed thin-section CT and pathologic specimens of biopsy-proven usual interstitial pneumonia (75 patients, 57 men and 18 women, mean age 60 years, range 29-83 years) and nonspecific interstitial pneumonia (44 patients, 9 men and 35 women, mean age 55 years, range 20-73 years). On review of CT and histopathologic specimens, diffuse dendriform ossification was identified in five (four men and one woman, age range 41-68 years, mean 58 years) of 75 patients (6.7%) with usual interstitial pneumonia. It was not seen in any of 44 patients with nonspecific interstitial pneumonia. With thin-section CT (osteoporosis window; window width 818, level 273), disseminated dendriform pulmonary ossification was detected as multiple tiny calcifications in bibasilar subpleural lungs (100% sensitive and 100% specific when compared with histopathologic findings as the gold standard). The thin-section CT finding of multiple tiny calcifications in bibasilar subpleural lungs might be of some help in the differential diagnosis between usual interstitial pneumonia and nonspecific interstitial pneumonia, considering they were not seen in any patients with nonspecific interstitial pneumonia (0%, 0/44) in our series. (orig.)

  6. Joint recovery programme versus usual care - An economic evaluation of a clinical pathway for joint replacement surgery

    NARCIS (Netherlands)

    Brunenberg, DE; van Steyn, MJ; Sluimer, JC; Bekebrede, LL; Bulstra, SK; Joore, MA

    2005-01-01

    Objective: The objective of the present study was to determine the incremental cost-effectiveness of a clinical pathway for patients undergoing joint replacement, the Joint Recovery Programme (JRP), as compared with usual care. The existing care process was revised to contain costs and shorten

  7. Association Between Parental Barriers to Accessing a Usual Source of Care and Children's Receipt of Preventive Services.

    Science.gov (United States)

    Bellettiere, John; Chuang, Emmeline; Hughes, Suzanne C; Quintanilla, Isaac; Hofstetter, C Richard; Hovell, Melbourne F

    Preventive health services are important for child development, and parents play a key role in facilitating access to services. This study examined how parents' reasons for not having a usual source of care were associated with their children's receipt of preventive services. We used pooled data from the 2011-2014 National Health Interview Survey (n = 34 843 participants). Parents' reasons for not having a usual source of care were framed within the Penchansky and Thomas model of access and measured through 3 dichotomous indicators: financial barriers (affordability), attitudes and beliefs about health care (acceptability), and all other nonfinancial barriers (accessibility, accommodation, and availability). We used multivariable logistic regression models to test associations between parental barriers and children's receipt of past-year well-child care visits and influenza vaccinations, controlling for other child, family, and contextual factors. In 2014, 14.3% (weighted percentage) of children had at least 1 parent without a usual source of care. Children of parents without a usual source of care because they "don't need a doctor and/or haven't had any problems" or they "don't like, trust, or believe in doctors" had 35% lower odds of receiving well-child care (adjusted odds ratio = 0.65; 95% CI, 0.56-0.74) and 23% lower odds of receiving influenza vaccination (adjusted odds ratio = 0.77; 95% CI, 0.69-0.86) than children of parents without those attitudes and beliefs about health care. Financial and other nonfinancial parental barriers were not associated with children's receipt of preventive services. Results were independent of several factors relevant to children's access to preventive health care, including whether the child had a usual source of care. Parents' attitudes and beliefs about having a usual source of care were strongly associated with their children's receipt of recommended preventive health services. Rates of receipt of child preventive

  8. Coffee Drinking Is Widespread in the United States, but Usual Intake Varies by Key Demographic and Lifestyle Factors123

    Science.gov (United States)

    Loftfield, Erikka; Freedman, Neal D; Dodd, Kevin W; Vogtmann, Emily; Xiao, Qian; Sinha, Rashmi; Graubard, Barry I

    2016-01-01

    Background: Despite widespread popularity and possible health effects, the prevalence and distribution of coffee consumption in US adults are poorly characterized. Objective: We sought to estimate usual daily coffee intakes from all coffee-containing beverages, including decaffeinated and regular coffee, among US adults according to demographic, socioeconomic, and health-related factors. Methods: Dietary intake data from ≤2 nonconsecutive 24-h dietary recalls and a food-frequency questionnaire administered during the NHANES 2003–2006 were used to estimate the person-specific probability of consuming coffee on a particular day and the usual amount consumed on consumption days. Trends in population mean coffee consumption over time were evaluated by using multiple linear regression and 1-d 24-h recall data from NHANES 2003–2012. Analyses were weighted to be representative of the US adult population aged ≥20 y. Results: An estimated 154 million adults, or 75% of the US population, aged ≥20 y reported drinking coffee; 49% reported drinking coffee daily. Prevalence did not vary by sex, education, income, or self-reported general health (all P ≥ 0.05) but did vary by age, race/ethnicity, smoking status, and alcohol drinking (all P coffee drinkers, the mean ± SE usual intake was 14.1 ± 0.5 fluid ounces/d (417 ± 15 mL/d). Mean usual intakes were higher in men than women, in older age groups than in those aged 20 to coffee consumption was stable from 2003 to 2012 (P-trend = 0.09). Conclusions: Coffee is widely consumed in the United States, with usual intakes varying by lifestyle and demographic factors, most notably by age. Longitudinal studies are needed to determine whether observed differences by age reflect birth cohort effects or changes in drinking patterns over the lifetime. PMID:27489008

  9. Usual Intake of Added Sugars and Saturated Fats Is High while Dietary Fiber Is Low in the Mexican Population.

    Science.gov (United States)

    López-Olmedo, Nancy; Carriquiry, Alicia L; Rodríguez-Ramírez, Sonia; Ramírez-Silva, Ivonne; Espinosa-Montero, Juan; Hernández-Barrera, Lucia; Campirano, Fabricio; Martínez-Tapia, Brenda; Rivera, Juan A

    2016-09-01

    The Mexican National Health and Nutrition Survey (ENSANUT) was carried out in 2012. Information from the survey is used to design and evaluate food and nutrition policies in Mexico. The objective of this study was to estimate the usual intake of energy and macronutrients in the Mexican population by using the ENSANUT 2012. Twenty-four-hour recall interviews were administered to a nationally representative subsample of 10,096 individuals aged ≥1 y from the ENSANUT 2012. Usual intake distributions and the prevalence of inadequate intakes were estimated by using the Iowa State University method. Student's t tests and tests on the equality of proportions were used to compare usual intakes and prevalence of inadequacy across socioeconomic status, area (rural or urban), and region of residence (North, Center, or South). Energy and macronutrient intakes and indicators of dietary adequacy are presented for children (ages 1-4 y and 5-11 y), adolescents (12-19 y), and adults (≥20 y). At the national level, the estimated mean fiber intake was below the Adequate Intake for all population subgroups, suggesting inadequacies. The estimated proportion with a usual added sugars intake of >10% of total energy intake was >64% in all age groups. The proportion with a usual saturated fat intake of >10% of total energy intake was estimated to be >78% in children, >66% in adolescents, and >50% in adults. Overall, fiber intake was lower and intakes of saturated fat and added sugars were higher in urban compared with rural areas, in the North compared with South regions, and among those with high compared with low socioeconomic status (P 50% of the Mexican population aged ≥1 y. These results highlight the importance of improving the diets of the overall population to reduce the risk of noncommunicable chronic diseases. © 2016 American Society for Nutrition.

  10. As intervenções do enfermeiro e as complicações em sala de recuperação pós-anestésica Las intervenciones del enfermero y las complicaciones en la sala de recuperación postanestésica Nurse interventions and the complications in the post-anesthesia recovery room

    Directory of Open Access Journals (Sweden)

    Débora Cristina Silva Popov

    2009-12-01

    Full Text Available Este estudo objetivou identificar complicações prevalentes em Sala de Recuperação Pós-Anestésica (SRPA; relacionar as complicações às intervenções de enfermagem realizadas; relacionar o esquema de jornada de trabalho dos enfermeiros às complicações. A amostra compôs-se de 400 prontuários de pacientes maiores de 18 anos, submetidos a procedimentos cirúrgicos de grande e médio porte, admitidos na unidade de SRPA, com tempo de permanência superior à uma hora. As complicações prevalentes foram: dor e hipotermia. Complicações que apresentaram relação estatisticamente significante com intervenção de enfermagem - dor: rotina, oxigenioterapia, medicação e curativo; agitação/ansiedade: rotina e oxigenioterapia; hipotensão: hidratação, exames complementares e observação; hipertensão: observação; tremor: manta térmica, transfusão sanguínea; náuseas/vômitos: rotina, medicação e sondagem vesical de alívio; sangramento: rotina, medicação e curativos; hipoxemia: rotina e oxigenioterapia; hipotermia: rotina, manta térmica e medicação. A dor, náuseas/vômitos, agitação e sangramento obtiveram relação estatisticamente significante com o enfermeiro fixo em SRPA.Este estudio objetivó identificar las complicaciones prevalentes en la Sala de Recuperación Postanestésica (SRPA; relacionar las complicaciones a las intervenciones de enfermería realizadas; relacionar el esquema de jornada de trabajo de los enfermeros con las complicaciones. La muestra estuvo compuesta de 400 fichas de pacientes mayores de 18 años, sometidos a procedimientos quirúrgicos de grande y medio porte, admitidos en la unidad de SRPA, con tiempo de permanencia superior a una hora. Las complicaciones prevalentes fueron: dolor e hipotermia. Complicaciones que presentaron relación estadísticamente significativa con la intervención de enfermería - dolor: rutina, oxigenoterapia, medicación y curativo; agitación/ansiedad: rutina y

  11. Disasters as Usual

    DEFF Research Database (Denmark)

    Albris, Kristoffer

    In this thesis, I explore how citizens and public institutions have adjusted to recent recurring floods in Dresden. As a riverine city, Dresden regularly experienced damaging floods throughout its history, right up until the start of the Second World War. Then something strange happened. Although...... the future as being fraught with uncertainty. This has implications both for how people understand themselves as members of society as well as for the relationship between the state and civil society. In other words, floods in Dresden have a social, political and public life. Rather than seeing disasters...

  12. Beyond business as usual

    Energy Technology Data Exchange (ETDEWEB)

    Popowich, J. [Elk Valley Coal Corporation, Calgary, AB (Canada). Fording Canadian Coal Trust

    2006-07-01

    The average hard coking coal price at Elk Valley Coal for the period 1980-2005 is shown on a graph. Innovation is essential to mining success. A company needs to put together a product that is better than the competition's. Other challenges include global competition, increasingly difficult mining conditions, complexity of the product demanded by the customer, logistics and transportation, personnel shortages, and shortages due to growth demand. Innovation requires observation, communication, and an environment receptive to change. Potential areas for mining innovation include operational excellence, management practices, organizational structure, technology, and people. 10 figs.

  13. Not the usual sinusitis

    Science.gov (United States)

    Ammar, Hussam; Kott, Amy; Fouda, Ragai

    2012-01-01

    An encephalocele is a protrusion of the cranial contents beyond the normal confines of the skull. It is a rare cause of seizure in adults. A 38-year-old woman presented with a first-onset seizure. Brain CT was interpreted as right frontal sinus opacification suggestive of sinusitis. The patient was discharged home with an amoxicillin prescription. A few days later, she was re-admitted with another seizure. Careful evaluation of the brain CT and MRI revealed a right frontal sinus posterior wall defect and possible brain encephalocele. The patient had complained of chronic nasal discharge for years and had also noticed a watery discharge from her right nostril. We suspected cerebrospinal fluid rhinorrhea. A bifrontal craniotomy was performed, the encephalocele was resected and cranialisation of the frontal sinus was completed. The patient remained free of seizures at the last follow-up. PMID:23188840

  14. Abordaje transparotídeo para la reducción abierta de las fracturas subcondíleas: Técnica quirúrgica y análisis de sus complicaciones Transparotid approach for the open reduction of subcondylar fractures: Surgical technique and analysis of complications

    Directory of Open Access Journals (Sweden)

    J. Rodríguez Flores

    2011-03-01

    Full Text Available Introducción: Existen varias opciones para el tratamiento de las fracturas subcondíleas. El abordaje transparotídeo anterior es una de las posibilidades terapéuticas para su reducción abierta y su fijación interna. El objetivo de este artículo es realizar una descripción de la técnica quirúrgica y analizar las complicaciones asociadas. Material y métodos: Se realizó una revisión clínica sobre un total de 31 pacientes con 34 fracturas subcondíleas, todas ellas tratadas quirúrgicamente con un abordaje transparotídeo anterior, usando placas y tornillos de osteosíntesis. Resultados: No se registraron complicaciones de ningún tipo en 22 de los 31 pacientes (70,97%, con buena oclusión posquirúrgica en 28 de ellos (90,32%. Las complicaciones relacionadas con el abordaje en nuestra serie de casos fueron las siguientes: 2 casos de paresia facial (5,88%, que en ambos fue leve y transitoria; 6 casos de fístula salival (17,65%, siendo en todos ellos autolimitadas, y 3 infecciones de la herida quirúrgica (8,82%: 2 resueltas con antibióticos y una que requirió también drenaje quirúrgico. Como complicación no relacionada con el tipo de abordaje sino con el tipo de osteosíntesis, hubo 2 casos de fractura de placa de osteosíntesis (5,88%. Conclusiones: El abordaje transparotídeo anterior es seguro, con un bajo riesgo lesivo para el nervio facial. Esta técnica proporciona un adecuado campo quirúrgico que permite la colocación y la fácil fijación de una segunda placa de osteosíntesis en la parte anterior de la fractura. La cicatriz resultante es estética.Introduction: Several options exist for the treatment of subcondylar jaw fractures. The anterior transparotid approach is one of the therapeutic options for open reduction and internal fixation. The aim of this communication was to describe the surgical technique and analyze the related complications. Patients and methods: A clinical review was made of 31 patients with 34

  15. Complicações respiratórias em pacientes com paralisia cerebral submetidos à anestesia geral Complicaciones respiratorias en pacientes con parálisis cerebral sometidos a la anestesia general Respiratory complications in patients with cerebral palsy undergoing general anesthesia

    Directory of Open Access Journals (Sweden)

    Sérgio Silva de Mello

    2007-10-01

    álisis cerebral (PC puede representar un desafío para el anestesiólogo. Este estudio prospectivo tuvo como objetivo determinar la prevalencia y el riesgo de complicaciones respiratorias en niños con PC sometidos a anestesia general inhalatoria para tomografía computadorizada. MÉTODO: Participaron del estudio pacientes con edades entre 1 y 17 años, estado físico ASA I a III, sometidos a AGI con sevoflurano y máscara laríngea para TC en el período de junio/2002 a junio/ 2003, divididos en 3 grupos: PC tetraplégicos (PCT, Otros tipos de PC (PCO, y paciente sin PC (NPC. Los padres o responsables respondieron a un cuestionario con preguntas sobre el historial médico de los pacientes, infección de vías aéreas superiores (IVAS, asma, convulsión, no coordinación oro faríngea, reflujo gastroesofágico, etc. Datos sobre la incidencia y la gravedad de las complicaciones respiratorias fueron recolectados proscpectivamente (tos, bronco espasmo, laringo espasmo, hipoxemia, aspiración. La muestra fue calculada para una incidencia esperada de 5% en el grupo NPC, con una diferencia de 15% entre los grupos (alfa = 0,05 y beta = 0,1, utilizando los tests del Chi-cuadrado, exacto de Fisher y t de Student. RESULTADOS: Conformaron la muestra 290 pacientes divididos en los grupos de la siguiente forma: PCT - 100, PCO - 79 y NPC- 111. No hubo diferencia en la prevalencia de complicaciones respiratorias entre los grupos PCT (4%, PCO (8,9% y NPC (7,3%. Hubo una asociación entre la presencia de IVAS y la incidencia de complicaciones (riesgo relativo 10,71. CONCLUSIONES: Niños con parálisis cerebral tipo tetraplegia espástica no parecen correr riesgo aumentado de complicaciones respiratorias durante la anestesia general inhalatoria con sevoflurano y máscara laríngea. El estudio confirma IVAS como factor de riesgo para la incidencia de esas complicaciones.BACKGROUND AND OBJETIVES: Anesthesia in patients with cerebral palsy (CP poses a challenge for the anesthesiologist. The objective

  16. Control and chronic complications of diabetes mellitus in an outpatient atention center in Medellín, Colombia, 1998-2001 Control y complicaciones crónicas de la diabetes mellitus en el Centro de Atención Ambulatorio central, Instituto de Seguro Social 1998-2001

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    Catalina Bedoya Gómez

    2004-01-01

    were: cardiovascular 48,4%, eyerelated 57.4%, renal 31,5%, neuropathy 28,6% and diabetic foot 24%. Less than 50% of the patients had reached goals in controlling glycemia, HbA1c, total cholesterol, HDL cholesterol and systolic blood pressure. In the control of triglycerides and diastolic blood pressure, 62% and 76.3%, respectively had reached the goals of control. When association tests among different variables were performed, we only found association between the type of diabetes and the presence of hypertension and cardiovascular disease (p <0.000 for both. Conclusions: in diabetic patients attending the outpatient diabetes control program of the iss sectional Antioquia, diabetes is associated to other metabolic syndrome components in high proportion; these patients have a high incidence of chronic complications which varies from 24 to 58%, thus enhancing their morbility and mortality and they represent an important burden to the health system. We emphasize on the need of early detection in order to do a proper control and to carry out therapeutic and educational strategies to prevent or slow down the appearance of complications. El control de la diabetes mellitus requiere la evaluación continua y estricta de un gran número de factores que lo afectan, no solo desde el punto de vista de la glucemia sino de otros participantes en el trastorno metabólico por ella producida, de otras enfermedades asociadas a ella y de hábitos de salud que influyen en su control y en la aparición de diferentes complicaciones. Para identificar esta situación en el programa de diabetes del Centro de Atención Ambulatoria (CAA central del Instituto del Seguro Social (ISS, seccional Antioquia se evaluaron el control de la diabetes, la presencia de enfermedades asociadas, los hábitos de salud, las complicaciones crónicas presentadas y el grado de control de los diferentes parámetros. Metodología: entre enero de 1998 y diciembre de 2001, mediante un muestreo aleatorio simple con

  17. No more 'business as usual' with audit and feedback interventions: towards an agenda for a reinvigorated intervention.

    Science.gov (United States)

    Ivers, Noah M; Sales, Anne; Colquhoun, Heather; Michie, Susan; Foy, Robbie; Francis, Jill J; Grimshaw, Jeremy M

    2014-01-17

    Audit and feedback interventions in healthcare have been found to be effective, but there has been little progress with respect to understanding their mechanisms of action or identifying their key 'active ingredients.' Given the increasing use of audit and feedback to improve quality of care, it is imperative to focus further research on understanding how and when it works best. In this paper, we argue that continuing the 'business as usual' approach to evaluating two-arm trials of audit and feedback interventions against usual care for common problems and settings is unlikely to contribute new generalizable findings. Future audit and feedback trials should incorporate evidence- and theory-based best practices, and address known gaps in the literature. We offer an agenda for high-priority research topics for implementation researchers that focuses on reviewing best practices for designing audit and feedback interventions to optimize effectiveness.

  18. Self-managed loaded exercise versus usual physiotherapy treatment for rotator cuff tendinopathy: a pilot randomised controlled trial.

    Science.gov (United States)

    Littlewood, Chris; Malliaras, Peter; Mawson, Sue; May, Stephen; Walters, Stephen J

    2014-03-01

    Rotator cuff tendinopathy is a common source of shoulder pain characterised by persistent and/or recurrent problems for a proportion of sufferers. The aim of this study was to pilot the methods proposed to conduct a substantive study to evaluate the effectiveness of a self-managed loaded exercise programme versus usual physiotherapy treatment for rotator cuff tendinopathy. A single-centre pragmatic unblinded parallel group pilot randomised controlled trial. One private physiotherapy clinic, northern England. Twenty-four participants with rotator cuff tendinopathy. The intervention was a programme of self-managed loaded exercise. The control group received usual physiotherapy treatment. Baseline assessment comprised the Shoulder Pain and Disability Index (SPADI) and the Short-Form 36, repeated three months post randomisation. The recruitment target was met and the majority of participants (98%) were willing to be randomised. 100% retention was attained with all participants completing the SPADI at three months. Exercise adherence rates were excellent (90%). The mean change in SPADI score was -23.7 (95% CI -14.4 to -33.3) points for the self-managed exercise group and -19.0 (95% CI -6.0 to -31.9) points for the usual physiotherapy treatment group. The difference in three month SPADI scores was 0.1 (95% CI -16.6 to 16.9) points in favour of the usual physiotherapy treatment group. In keeping with previous research which indicates the need for further evaluation of self-managed loaded exercise for rotator cuff tendinopathy, these methods and the preliminary evaluation of outcome offer a foundation and stimulus to conduct a substantive study. Copyright © 2013 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  19. The effect of interpersonal psychotherapy and other psychodynamic therapies versus 'treatment as usual' in patients with major depressive disorder.

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    Janus Christian Jakobsen

    Full Text Available BACKGROUND: Major depressive disorder afflicts an estimated 17% of individuals during their lifetimes at tremendous suffering and costs. Interpersonal psychotherapy and other psychodynamic therapies may be effective interventions for major depressive disorder, but the effects have only had limited assessment in systematic reviews. METHODS/PRINCIPAL FINDINGS: Cochrane systematic review methodology with meta-analysis and trial sequential analysis of randomized trials comparing the effect of psychodynamic therapies versus 'treatment as usual' for major depressive disorder. To be included the participants had to be older than 17 years with a primary diagnosis of major depressive disorder. Altogether, we included six trials randomizing a total of 648 participants. Five trials assessed 'interpersonal psychotherapy' and only one trial assessed 'psychodynamic psychotherapy'. All six trials had high risk of bias. Meta-analysis on all six trials showed that the psychodynamic interventions significantly reduced depressive symptoms on the 17-item Hamilton Rating Scale for Depression (mean difference -3.12 (95% confidence interval -4.39 to -1.86;P<0.00001, no heterogeneity compared with 'treatment as usual'. Trial sequential analysis confirmed this result. DISCUSSION: We did not find convincing evidence supporting or refuting the effect of interpersonal psychotherapy or psychodynamic therapy compared with 'treatment as usual' for patients with major depressive disorder. The potential beneficial effect seems small and effects on major outcomes are unknown. Randomized trials with low risk of systematic errors and low risk of random errors are needed.

  20. Avoidance of Vitamin K-Rich Foods Is Common among Warfarin Users and Translates into Lower Usual Vitamin K Intakes.

    Science.gov (United States)

    Leblanc, Cristina; Dubé, Marie-Pierre; Presse, Nancy; Dumas, Stéphanie; Nguyen, Mimosa; Rouleau-Mailloux, Étienne; Perreault, Sylvie; Ferland, Guylaine

    2016-06-01

    Warfarin users should aim for stable daily vitamin K intakes. However, some studies report that patients are often advised to avoid eating green vegetables. Whether this advice impacts vitamin K intakes is unknown. Our aim was to describe the nature and sources of vitamin K-related dietary recommendations that patients received at the initiation of warfarin therapy, assess their adherence to these recommendations, and examine whether usual vitamin K intakes vary according to these recommendations. We conducted a retrospective cohort study with patients enrolled in the Québec Warfarin Cohort Study. Patients were asked to report dietary recommendations they had received at warfarin initiation and their adherence to these recommendations. Usual vitamin K intakes were assessed using a validated semi-quantitative food frequency questionnaire. Three hundred seventeen patients aged 36 to 97 years who initiated warfarin between 2011 and 2012 and were treated for 12 months or longer with a target international normalized ratio range of 2.0 to 3.0 or 2.5 to 3.5. Patients were classified according to vitamin K-related recommendations reported: limit or avoid vitamin K-rich foods; aim for stable consumption of vitamin K-rich foods; or no vitamin K-related advice. A one-way analysis of covariance was used to compare mean usual vitamin K intakes between patients after adjustment for covariates. Most patients (68%) reported being advised to limit or avoid vitamin K-rich foods, particularly green vegetables, 10% reported being advised to aim for stable consumption of vitamin K-rich foods, and 22% did not recall receiving any vitamin K-related recommendation. Mean usual vitamin K intakes of patients adhering to the recommendation to limit or avoid vitamin K-rich foods was 35% to 46% lower than those of other patients (Pvitamin K-rich foods, which translated into lower usual vitamin K intakes. Copyright © 2016 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All

  1. Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial.

    Science.gov (United States)

    Sciurba, Frank C; Criner, Gerard J; Strange, Charlie; Shah, Pallav L; Michaud, Gaetane; Connolly, Timothy A; Deslée, Gaëtan; Tillis, William P; Delage, Antoine; Marquette, Charles-Hugo; Krishna, Ganesh; Kalhan, Ravi; Ferguson, J Scott; Jantz, Michael; Maldonado, Fabien; McKenna, Robert; Majid, Adnan; Rai, Navdeep; Gay, Steven; Dransfield, Mark T; Angel, Luis; Maxfield, Roger; Herth, Felix J F; Wahidi, Momen M; Mehta, Atul; Slebos, Dirk-Jan

    Preliminary clinical trials have demonstrated that endobronchial coils compress emphysematous lung tissue and may improve lung function, exercise tolerance, and symptoms in patients with emphysema and severe lung hyperinflation. To determine the effectiveness and safety of endobronchial coil treatment. Randomized clinical trial conducted among 315 patients with emphysema and severe air trapping recruited from 21 North American and 5 European sites from December 2012 through November 2015. Participants were randomly assigned to continue usual care alone (guideline based, including pulmonary rehabilitation and bronchodilators; n = 157) vs usual care plus bilateral coil treatment (n = 158) involving 2 sequential procedures 4 months apart in which 10 to 14 coils were bronchoscopically placed in a single lobe of each lung. The primary effectiveness outcome was difference in absolute change in 6-minute-walk distance between baseline and 12 months (minimal clinically important difference [MCID], 25 m). Secondary end points included the difference between groups in 6-minute walk distance responder rate, absolute change in quality of life using the St George's Respiratory Questionnaire (MCID, 4) and change in forced expiratory volume in the first second (FEV1; MCID, 10%). The primary safety analysis compared the proportion of participants experiencing at least 1 of 7 prespecified major complications. Among 315 participants (mean age, 64 years; 52% women), 90% completed the 12-month follow-up. Median change in 6-minute walk distance at 12 months was 10.3 m with coil treatment vs -7.6 m with usual care, with a between-group difference of 14.6 m (Hodges-Lehmann 97.5% CI, 0.4 m to ∞; 1-sided P = .02). Improvement of at least 25 m occurred in 40.0% of patients in the coil group vs 26.9% with usual care (odds ratio, 1.8 [97.5% CI, 1.1 to ∞]; unadjusted between-group difference, 11.8% [97.5% CI, 1.0% to ∞]; 1-sided P = .01). The between-group difference in

  2. Mycotrophy in Gilliesieae, a threatened and poorly known tribe of Alliaceae from central Chile Micotrofía en Gilliesieae, una tribu amenazada y poco conocida de Alliaceae de Chile central

    Directory of Open Access Journals (Sweden)

    GUSTAVO A TORRES-MELLADO

    2012-06-01

    Full Text Available The five known genera of Gilliesieae have their diversity center in the Mediterranean zone of central Chile, where many of their habitats are threatened by urban expansion, industrial and agroforestry activities, as well as other anthropogenic impacts. Very little is known about the biology of these particular geophytes, the majority of which currently have either vulnerable or endangered status, mainly due to their dispersed and small populations generally associated to remnants of native vegetation. As mycorrhizal associations are essential for soil resource acquisition and stress mitigation in most plants, our objective was to assess the hitherto unknown mycotrophic status of ten species of Gilliesieae from central Chile by qualitative and quantitative assessment of intraradical fungal structures. All sampled genera (Gethyum, Gilliesia, Miersia, Solaria, Speea showed regular presence of arbuscular mycorrhiza, while other mycorrhizal or putatively mutualistic associations, like dark septate endophytes, were practically absent. Mycorrhizal colonization of fine roots reached a mean of ca. 45 % across all examined taxa, with highly variable values ranging from 9 % to 82 % in Miersia tenuiseta and Gilliesia curicana, respectively. The high level of mycorrhization indicates that arbuscular mycorrhiza should be considered for conservation strategies of threatened species or biotechnological use in plant propagation. The main future task is the identification of the associated fungal taxa.Los cinco géneros conocidos de Gilliesieae tienen su centro de diversidad en la zona mediterránea de Chile central, donde muchos de sus hábitats están amenazados por la expansión urbana, actividades industriales y agroforestales, así como otros impactos antropogénicos. Se sabe muy poco sobre la biología de estas particulares geófitas, que en la actualidad tienen en su mayoría estatus de vulnerable o en peligro de extinción, debido a sus poblaciones

  3. Modelo de simulación del balance hídrico en suelos con freática poco profunda Water balance simulation model in shallow watertable soils

    Directory of Open Access Journals (Sweden)

    Américo Degioanni

    2006-07-01

    Full Text Available Los suelos con capa freática poco profunda poseen mayor probabilidad de ser afectados por anegamiento. La predicción de la oscilación temporal del nivel freático constituye una importante herramienta para valorar el riesgo de ocurrencia de tal proceso. El objetivo de este trabajo es presentar los fundamentos teóricos, la estructura operativa y la capacidad predictiva del modelo de simulación del balance hídrico Freat.1. El modelo se fundamenta en el cálculo de la transferencia de agua entre la atmósfera, el perfil del suelo, la vegetación y la capa freática. Los procesos de transferencia simulados son: escurrimiento superficial saliente, ascenso del nivel freático por efecto de la lluvia neta y del escurrimiento subterráneo entrante y descenso del nivel freático por efectos del escurrimiento subterráneo saliente, evaporación, ascenso capilar desde la capa freática y transpiración de la vegetación. Se evalúan los resultados de su aplicación en un Haplustol udorténtico y en un Natralbol típico ambos con freática oscilando a menos de tres metros de profundidad. El error de predicción estimado como la raíz del error cuadrático medio entre registros freáticos observados y simulados es menor de 15 cm para ambos suelos. Se concluye que el modelo resulta apropiado para predecir oscilaciones temporales de capa freática y evaluar el riesgo de inundación por anegamiento en suelos con capa freática cercana a la superficie.Soils with shallow water table have greater probability of being affected by waterlogging. The prediction of the water table depth temporal oscillation is an important tool to assess the risk of occurrence of such processes. The goal of this paper is to present the theoretical foundations, operative structure and predictive capacity of the water balance simulation model Freat.1. This model is based on the calculus of water transference between atmosphere, soil profile, vegetation and water table. The

  4. Complicações microvasculares e disfunção autonômica cardíaca em pacientes com diabete melito tipo 1 Complicaciones microvasculares y disfunción autonómica cardíaca en pacientes con diabetes mellittus tipo 1 Microvascular complications and cardiac autonomic dysfunction in patients with diabetes mellitus type 1

    Directory of Open Access Journals (Sweden)

    Fernando K Almeida

    2011-06-01

    Full Text Available FUNDAMENTO: A presença de neuropatia autonômica cardíaca (NAC em pacientes com diabete melito (DM está associada a aumento da mortalidade e a complicações crônicas microvasculares do diabete. OBJETIVO: Investigar uma possível associação entre achados sugestivos de NAC durante a realização do teste ergométrico (TE e nefropatia e retinopatia em pacientes com DM tipo 1. MÉTODOS: Realizamos um estudo transversal com 84 pacientes com DM tipo 1. Todos os pacientes foram submetidos à avaliação clínica e laboratorial e realizaram TE, sendo que aqueles que apresentaram achados sugestivos de isquemia miocárdica foram excluídos da análise dos dados (n = 3. A avaliação de complicações microvasculares (retinopatia e nefropatia foi realizada na amostra. RESULTADOS: Os pacientes com nefropatia e aqueles com retinopatia atingiram uma frequência cardíaca (FC durante o pico de exercício (FC máxima menor e apresentaram aumento menor da FC em relação ao repouso (ΔFC pico quando comparados com aqueles sem estas complicações. Esses pacientes também apresentaram menor redução da FC no segundo e 4º minutos após o final do teste (ΔFC recuperação dois e 4 minutos. Após realização de análise multivariada com controle para os possíveis fatores de confusão, os ΔFC recuperação em dois e 4 minutos, FC máxima e o ΔFC pico permaneceram significativamente associados à retinopatia; e os ΔFC recuperação no segundo e 4º minutos permaneceram associados à presença de nefropatia. CONCLUSÃO: O TE pode ser considerado um instrumento adicional para a detecção precoce de NAC e para identificar pacientes em maior risco para complicações microvasculares do diabete.BACKGROUND: LA presencia de neuropatía autonómica cardíaca (NAC en pacientes con diabetes mellittus (DM está asociada a aumento de la mortalidad y a complicaciones crónicas microvasculares de diabetes. OBJECTIVE: Investigar una posible asociación entre

  5. Cocaína: complicaciones obstétricas, médicas y perinatales. Características clínicas y tratamiento a estas pacientes Cocaine: obstetric, medical and perinatal complications. Clinical characteristics and treatment of these patients

    Directory of Open Access Journals (Sweden)

    Miguel Lugones Botell

    2005-08-01

    Full Text Available Se realizó una revisión sobre los efectos generales de la cocaína, y en particular, sobre el embarazo y el recién nacido, en la que se enfatiza en los efectos deletéreos que tiene esta droga sobre la gestación, entre los que se destacan el bajo peso al nacer, el hematoma retroplacentario, la hipertensión arterial y la muerte fetal, entre otras complicaciones, así como también las consecuencias negativas que provoca sobre el producto de la concepción. Se hacen consideraciones acerca del manejo integral que hay que tener sobre estas pacientes.A review on the general effects of cocaine and, in particular, on its effects on pregnancy and the newborn infant, was made. Low birth weight, retroplacental hematoma, arterial hypertension and fetal death, are some of the deleterious effects of this drug on gestation that were emphazised, among other complications, as well as its negative consequences for the product of conception. Considerations are made on the comprehensive management of these patients.

  6. Comparative Effectiveness of Usual Source of Care Approaches to Improve End-of-Life Outcomes for Children With Intellectual Disability.

    Science.gov (United States)

    Lindley, Lisa C; Cozad, Melanie J

    2017-09-01

    Children with intellectual disability (ID) are at risk for adverse end-of-life outcomes including high emergency room utilization and hospital readmissions, along with low hospice enrollment. The objective of this study was to compare the effectiveness of usual source of care approaches to improve end-of-life outcomes for children with ID. We used longitudinal California Medicaid claims data. Children were included who were 21 years with fee-for-service Medicaid claims, died between January 1, 2007, and December 31, 2010, and had a moderate-to-profound ID diagnosis. End-of-life outcomes (i.e., hospice enrollment, emergency room utilization, hospital readmissions) were measured via claims data. Our treatments were usual source of care (USC) only vs. usual source of care plus targeted case management (USC plus TCM). Using instrumental variable analysis, we compared the effectiveness of treatments on end-of-life outcomes. Ten percent of children with ID enrolled in hospice, 73% used the emergency room, and 20% had three or more hospital admissions in their last year of life. USC plus TCM relative to USC only had no effect on hospice enrollment; however, it significantly reduced the probability of emergency room utilization (B = -1.29, P life outcomes for children with ID. Further study of the extent of UCS and TCM involvement in reducing emergency room utilization and hospital readmissions at end of life is needed. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  7. Effectiveness of a multifaceted implementation strategy compared to usual care on low back pain guideline adherence among general practitioners.

    Science.gov (United States)

    Suman, Arnela; Schaafsma, Frederieke G; van de Ven, Peter M; Slottje, Pauline; Buchbinder, Rachelle; van Tulder, Maurits W; Anema, Johannes R

    2018-05-11

    To improve patient care, and to reduce unnecessary referrals for diagnostic imaging and medical specialist care for low back pain, an evidence-based guideline for low back pain was developed in the Netherlands in 2010. The current study evaluated the effect of a multifaceted implementation strategy on guideline adherence among Dutch general practitioners. The implementation strategy included a multidisciplinary training, provision of educational material and an interactive website for healthcare professionals, supported by a multimedia eHealth intervention for patients with low back pain. Adherence was measured using performance indicators based on 3 months data extracted from the contacts with patients with low back pain recorded in the electronic medical records of participating general practitioners. Performance indicators were compared between two groups: a usual care group and an implementation group. Performance indicators were referrals to consultations with medical specialists, to diagnostic imaging, and to psychosocial and/or occupational physician consultations, and inquiries about psychosocial and occupational risk factors. The electronic medical records of 5130 patient contacts for LBP were analysed; 2453 patient contacts in the usual care group and 2677 patient contacts in the implementation group. Overall, rates of referral and of recorded inquiries regarding psychosocial and occupational risk factors remained low in both groups over time. The only statistically significant difference found was a reduction in the number of referrals to neurologists in the implementation group (from 100 (7%) to 50 (4%)) compared to the usual care group (from 48 (4%) to 50 (4%), (p strategy did not result in improved guideline adherence among general practitioners, and it is not recommended for widespread use. However, baseline referral rates in participating practices were already low, possibly leaving only little room for improvement. Inquiries for psychosocial and

  8. Cost-effectiveness Analysis of an Aftercare Service vs Treatment-As-Usual for Patients with Severe Mental Disorders.

    Science.gov (United States)

    Barfar, Eshagh; Sharifi, Vandad; Amini, Homayoun; Mottaghipour, Yasaman; Yunesian, Masud; Tehranidoost, Mehdi; Sobhebidari, Payam; Rashidian, Arash

    2017-09-01

    There have been claims that community mental health principles leads to the maintenance of better health and functioning in patients and can be more economical for patients with severe and chronic mental disorders. Economic evaluation studies have been used to assess the cost-effectiveness of national health programs, or to propose efficient strategies for health care delivery. The current study is intended to test the cost-effectiveness of an Aftercare Service when compared with Treatment-As-Usual for patients with severe mental disorders in Iran. This study was a parallel group randomized controlled trial. A total of 160 post-discharge eligible patients were randomized into two equal patient groups, Aftercare Service (that includes either Home Visiting Care, or Telephone Follow-up for outpatient treatment) vs Treatment-As-Usual, using stratified balanced block randomization method. All patients were followed for 12 months after discharge. The perspective of the present study was the societal perspective. The outcome measures were the rate of readmission at the hospitals after discharge, psychotic symptoms, manic symptoms, depressive symptoms, illness severity, global functioning, quality of life, and patients' satisfaction with the services. The costs included the intervention costs and the patient and family costs in the evaluation period. There was no significant difference in effectiveness measures between the two groups. The Aftercare Service arm was about 66,000 US$ cheaper than Treatment-As-Usual arm. The average total cost per patient in the Treatment-As-Usual group was about 4651 USD, while it was reduced to 3823 US$ in the Aftercare Service group; equivalent to a cost reduction of about 800 USD per patient per year. Given that there was no significant difference in effectiveness measures between the two groups (slightly in favor of the intervention), the Aftercare Service was cost-effective. The most important limitation of the study was the relatively

  9. The effects of immunotherapy with intravenous immunoglobulins versus no intervention, placebo, or usual care in patients with recurrent miscarriages

    DEFF Research Database (Denmark)

    Egerup, Pia; Lindschou, Jane; Gluud, Christian

    2014-01-01

    , and publication status investigating infusions with immunoglobulins in relation to pregnancy compared to placebo, no intervention, or treatment as usual for assessments of benefits and harms. The relevant published literature will be searched using the following databases: Cochrane Central Register of Controlled...... Trials, Medline, Embase, WHO International Clinical Trials Registry Platform, and Ovid Medline In-Process and Other Non-Indexed Citations databases. Two review authors will independently extract data and assess risk of bias. We will undertake meta-analyses according to the recommendations stated...

  10. Use of a radioactive substance, the depleted uranium, for the fabrication of enamels and usual things and jewels decoration

    International Nuclear Information System (INIS)

    1999-01-01

    This open letter to the ministers and State Secretaries of the public health, the environment and the consumers protection, deals with a complaint against X, lodged by the CRII-RAD. This complaint concerns the use of depleted uranium for the fabrication of enamels and the decoration of usual things and jewels. This utilization constitutes a breach of the decree 66-450, which forbids since 1966 the addition of radioactive substances in food, cosmetic and domestic products. The letter takes into account the hazards for the workers and the consumers, the uranium powder origin and discusses the guaranties forecast under the legislation eye. (A.L.B.)

  11. Study protocol: Cost-effectiveness of transmural nutritional support in malnourished elderly patients in comparison with usual care

    Directory of Open Access Journals (Sweden)

    van Bokhorst-de van der Schueren Marian AE

    2010-02-01

    Full Text Available Abstract Background Malnutrition is a common consequence of disease in older patients. Both in hospital setting and in community setting oral nutritional support has proven to be effective. However, cost-effectiveness studies are scarce. Therefore, the aim of our study is to investigate the effectiveness and cost-effectiveness of transmural nutritional support in malnourished elderly patients, starting at hospital admission until three months after discharge. Methods This study is a randomized controlled trial. Patients are included at hospital admission and followed until three months after discharge. Patients are eligible to be included when they are ≥ 60 years old and malnourished according to the following objective standards: Body Mass Index (BMI in kg/m2 Conclusion In this randomized controlled trial we will evaluate the effect of transmural nutritional support in malnourished elderly patients after hospital discharge, compared to usual care. Primary endpoints of the study are changes in activities of daily living, body weight, body composition, quality of life, and muscle strength. An economic evaluation will be performed to evaluate the cost-effectiveness of the intervention in comparison with usual care. Trial registration Netherlands Trial Register (ISRCTN29617677, registered 14-Sep-2005

  12. Response of the Pre-oriented Goal-directed Attention to Usual and Unusual Distractors: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Golnaz Baghdadi

    2017-03-01

    Full Text Available Introduction: In this study, we investigated the distraction power of the unusual and usual images on the attention of 20 healthy primary school children. Methods: Our study was different from previous ones in that the participants were asked to fix the initial position of their attention on a pre-defined location after being presented with unusual images as distractors. The goals were presented in locations, which were far from the attraction basin of distractors. Our expectation was that the pre-orienting of the attention to the position of targets can reduce the attractive effect of unusual images compared to the usual ones. The percentage of correct responses and the reaction time have been measured as behavioral indicators of attention performance. Results: Results showed that using the goal-directed attention, subjects ignored both kinds of distractors nearly the same way. Conclusion: With regard to previous reports about the more attraction towards the unusual images, it is suggested that the dynamics of the visual attention system be sensitive to the initial condition. That is, changing the initial position of the attention can lead to the decrement of the unusual images’ effects. However, several other possibilities such as a probable delay in processing unusual features could explain this observation, too. 

  13. The effect of interpersonal psychotherapy and other psychodynamic therapies versus 'treatment as usual' in patients with major depressive disorder.

    Science.gov (United States)

    Jakobsen, Janus Christian; Hansen, Jane Lindschou; Simonsen, Erik; Gluud, Christian

    2011-04-27

    Major depressive disorder afflicts an estimated 17% of individuals during their lifetimes at tremendous suffering and costs. Interpersonal psychotherapy and other psychodynamic therapies may be effective interventions for major depressive disorder, but the effects have only had limited assessment in systematic reviews. Cochrane systematic review methodology with meta-analysis and trial sequential analysis of randomized trials comparing the effect of psychodynamic therapies versus 'treatment as usual' for major depressive disorder. To be included the participants had to be older than 17 years with a primary diagnosis of major depressive disorder. Altogether, we included six trials randomizing a total of 648 participants. Five trials assessed 'interpersonal psychotherapy' and only one trial assessed 'psychodynamic psychotherapy'. All six trials had high risk of bias. Meta-analysis on all six trials showed that the psychodynamic interventions significantly reduced depressive symptoms on the 17-item Hamilton Rating Scale for Depression (mean difference -3.12 (95% confidence interval -4.39 to -1.86;Pinterpersonal psychotherapy or psychodynamic therapy compared with 'treatment as usual' for patients with major depressive disorder. The potential beneficial effect seems small and effects on major outcomes are unknown. Randomized trials with low risk of systematic errors and low risk of random errors are needed.

  14. Changes in executive functions and self-efficacy are independently associated with improved usual gait speed in older women

    Directory of Open Access Journals (Sweden)

    Hsu Chun

    2010-05-01

    Full Text Available Abstract Background Improved usual gait speed predicts substantial reduction in mortality. A better understanding of the modifiable factors that are independently associated with improved gait speed would ensure that intervention strategies are developed based on a valid theoretical framework. Thus, we examined the independent association of change in executive functions and change in falls-related self-efficacy with improved gait speed among community-dwelling senior women. Methods A secondary analysis of the 135 senior women aged 65 to 75 years old who completed a 12-month randomized controlled trial of resistance training. Usual gait speed was assessed using a 4-meter walk. Three executive processes were assessed by standard neuropsychological tests: 1 set shifting; 2 working memory; and 3 selective attention and response inhibition. A linear regression model was constructed to determine the independent association of change in executive functions and falls-related self-efficacy with change in gait speed. Results Improved selective attention and conflict resolution, and falls-related self-efficacy, were independently associated with improved gait speed after accounting for age, global cognition, baseline gait speed, and change in quadriceps strength. The total variance explained was 24%. Conclusions Interventions that target executive functions and falls-related self-efficacy, in addition to physical functions, to improve gait speed may be more efficacious than those that do not. Trial Registration ClinicalTrials.gov Identifier: NCT00426881

  15. Evaluation of the Relative Validity of the Short Diet Questionnaire for Assessing Usual Consumption Frequencies of Selected Nutrients and Foods

    Directory of Open Access Journals (Sweden)

    Bryna Shatenstein

    2015-08-01

    Full Text Available A 36-item Short Diet Questionnaire (SDQ was developed to assess usual consumption frequencies of foods providing fats, fibre, calcium, vitamin D, in addition to fruits and vegetables. It was pretested among 30 community-dwelling participants from the Québec Longitudinal Study on Nutrition and Successful Aging, “NuAge” (n = 1793, 52.4% women, recruited in three age groups (70 ± 2 years; 75 ± 2 years; 80 ± 2 years. Following revision, the SDQ was administered to 527 NuAge participants (55% female, distributed among the three age groups, both sexes and languages (French, English prior to the second of three non-consecutive 24 h diet recalls (24HR and validated relative to the mean of three 24HR. Full data were available for 396 participants. Most SDQ nutrients and fruit and vegetable servings were lower than 24HR estimates (p < 0.05 except calcium, vitamin D, and saturated and trans fats. Spearman correlations between the SDQ and 24HR were modest and significant (p < 0.01, ranging from 0.19 (cholesterol to 0.45 (fruits and vegetables. Cross-classification into quartiles showed 33% of items were jointly classified into identical quartiles of the distribution, 73% into identical and contiguous quartiles, and only 7% were frankly misclassified. The SDQ is a reasonably accurate, rapid approach for ranking usual frequencies of selected nutrients and foods. Further testing is needed in a broader age range.

  16. A review and analysis of renewable energy curtailment schemes and Principles of Access: Transitioning towards business as usual

    International Nuclear Information System (INIS)

    Kane, Laura; Ault, Graham

    2014-01-01

    In the last decade, the EU has driven forward the development and connection of renewable power sources across Europe. This has changed the way in which distribution networks operate, moving from a passive system, to a more active system where generation and demand are located closer together with system states being more complex and variable. Increased penetration of renewable generation into distribution networks is presenting a number of challenges to Distribution Network Operators (DNOs) including the provision of network access in capacity constrained networks. The introduction of Active Network Management (ANM) is enabling an increase in renewable generation connections through enhanced network access in otherwise ‘full’ networks. This paper presents a way in which DNOs might move towards Business as Usual (BAU) arrangements for ANM schemes. It is necessary to determine the curtailment arrangements, or Principles of Access (PoA), and from this estimate generation access under ANM and the flow of services and money for different scenarios. In this paper, a comprehensive literature review, detailed case study evaluation on early ANM schemes, quantitative curtailment assessment for different PoA and a qualitative analysis of business models for different ANM PoA is presented in turn with conclusions drawn from these three approaches. - Highlights: • Literature review of Principles of Access. • Detailed case study analysis of Principles of Access in ANM projects. • Quantitative analysis of different Principles of Access. • Proposed business models for ANM as business as usual

  17. Influence of usual zinc intake and zinc in a meal on 65Zn retention and turnover in the rat

    International Nuclear Information System (INIS)

    Hunt, J.R.; Johnson, P.E.; Swan, P.B.

    1987-01-01

    The influences of zinc in a meal and usual zinc intake on zinc retention and turnover were investigated in 7-wk-old male rats fed diets containing 12-151 mg Zn/kg for 3 wk before and after consuming a 65 Zn-labeled meal containing ZnCl 2 . Retention corrected to zero time and turnover rate were determined by whole-body counting. Percent zinc retention was inversely proportional to the natural logarithm of the meal zinc, between 0.09 and 26 mumol. In comparison to lower doses, higher doses resulted in lower percent retention but greater amounts of zinc retained. Although the latter relationship was slightly curvilinear, there was no indication of a limited capacity for zinc retention with high doses. However, doses above 4 mumol resulted in higher turnover rates in rats accustomed to lower zinc intakes. Percent retention and the reciprocal of the turnover rate were proportional to the reciprocal of the dietary zinc concentration. The greatest differences in retention and turnover occurred between 12 and 26 mg Zn/kg diet. The zinc dose in a meal and the usual dietary zinc separately influenced percent zinc retention. These factors also interacted, such that greater dose effects were observed at lower zinc intakes and greater dietary zinc effects were observed at lower doses

  18. <報文>レアメタル資源に関する研究(I) : ジルコニウム資源としてのPocos de Caldas, Brasil産カルダサイト

    OpenAIRE

    佐藤, 修彰; 伊藤, 良雅; 南條, 道夫

    1986-01-01

    The zirconium deposit of the Pocos de Caldas Plateau is north of Sa^^?o Paulo, Brasil, on the boundary between the States of Minas Gerais and Sa^^?o Paulo. The zirconium ore was formed as a mixture of baddeleyite (ZrO_2) and zircon (ZrSiO_4) which was identified as caldasite from the microscopic, X-ray and electron microprobe studies. This ore also contained a high content of uranium and thorium oxides, enough for nuclear fuel resources from the γ-ray spectrometry. The ore shows stable behavi...

  19. Conocimientos usuales de los pacientes diabéticos en los estudiantes de medicina del occidente de México Usual knowledge of medical students form Western Mexico on diabetic patients

    Directory of Open Access Journals (Sweden)

    Rafael Bustos Saldaña

    2007-12-01

    Full Text Available Objetivo: Identificar el conocimiento que presentan los estudiantes de Medicina acerca de los conceptos usuales de los pacientes diabéticos sobre su enfermedad. Material y métodos: Estudio descriptivo en 275 estudiantes de Medicina del Centro Universitario del Sur de la Universidad de Guadalajara. Se seleccionó la muestra en forma aleatoria a los alumnos inscritos en el calendario 2006 A, para aplicarles el instrumento Diabetes Knowledge Questionnaire (24. Se utilizó el programa de estadística EPI INFO 2000, se tomó una significancia estadística Objective: To identify the knowledge that presents Medicine students about the usual concepts of the diabetic patients on their disease. Material and Methods: Cross sectional study in 275 Medicine alumni of the University Center of the South of the University of Guadalajara. Sample was selected in randomized form in the students enrolled in calendar 2006 A, in order to apply them instrument Diabetes Knowledge Questionnaire (24. The statistic program was used EPI INFO 2000, a statistical significance was taken <0.05. Results: Students age: 20.03±1.9 years. The total average of guessed right answers was: 17.56± 3.24, students of 7º and 8º. cycle presented 19.53 ±2.15 and 19.75±1.92 right answers. As far as Basic knowledge of the disease 75,82% answered the reagents suitably, in glycemic control 70.7% and prevention measures and complications 71.9%. Conclusions: knowledge in Medicine students as far as the concepts that must have the diabetic patients on their disease increases in significant form as soon as it increases the semesters of study, the first scholastic cycles have the tendency to be similar to the population in regional diabetic patients.

  20. Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease.

    Science.gov (United States)

    Lenferink, Anke; Brusse-Keizer, Marjolein; van der Valk, Paul Dlpm; Frith, Peter A; Zwerink, Marlies; Monninkhof, Evelyn M; van der Palen, Job; Effing, Tanja W

    2017-08-04

    Chronic Obstructive Pulmonary Disease (COPD) self-management interventions should be structured but personalised and often multi-component, with goals of motivating, engaging and supporting the patients to positively adapt their behaviour(s) and develop skills to better manage disease. Exacerbation action plans are considered to be a key component of COPD self-management interventions. Studies assessing these interventions show contradictory results. In this Cochrane Review, we compared the effectiveness of COPD self-management interventions that include action plans for acute exacerbations of COPD (AECOPD) with usual care. To evaluate the efficacy of COPD-specific self-management interventions that include an action plan for exacerbations of COPD compared with usual care in terms of health-related quality of life, respiratory-related hospital admissions and other health outcomes. We searched the Cochrane Airways Group Specialised Register of trials, trials registries, and the reference lists of included studies to May 2016. We included randomised controlled trials evaluating a self-management intervention for people with COPD published since 1995. To be eligible for inclusion, the self-management intervention included a written action plan for AECOPD and an iterative process between participant and healthcare provider(s) in which feedback was provided. We excluded disease management programmes classified as pulmonary rehabilitation or exercise classes offered in a hospital, at a rehabilitation centre, or in a community-based setting to avoid overlap with pulmonary rehabilitation as much as possible. Two review authors independently assessed trial quality and extracted data. We resolved disagreements by reaching consensus or by involving a third review author. Study authors were contacted to obtain additional information and missing outcome data where possible. When appropriate, study results were pooled using a random-effects modelling meta-analysis. The primary

  1. Economic evaluation of a multifactorial, interdisciplinary intervention versus usual care to reduce frailty in frail older people.

    Science.gov (United States)

    Fairhall, Nicola; Sherrington, Catherine; Kurrle, Susan E; Lord, Stephen R; Lockwood, Keri; Howard, Kirsten; Hayes, Alison; Monaghan, Noeline; Langron, Colleen; Aggar, Christina; Cameron, Ian D

    2015-01-01

    To compare the costs and cost-effectiveness of a multifactorial interdisciplinary intervention versus usual care for older people who are frail. Cost-effectiveness study embedded within a randomized controlled trial. Community-based intervention in Sydney, Australia. A total of 241 community-dwelling people 70 years or older who met the Cardiovascular Health Study criteria for frailty. A 12-month multifactorial, interdisciplinary intervention targeting identified frailty characteristics versus usual care. Health and social service use, frailty, and health-related quality of life (EQ-5D) were measured over the 12-month intervention period. The difference between the mean cost per person for 12 months in the intervention and control groups (incremental cost) and the ratio between incremental cost and effectiveness were calculated. A total of 216 participants (90%) completed the study. The prevalence of frailty was 14.7% lower in the intervention group compared with the control group at 12 months (95% CI 2.4%-27.0%; P = .02). There was no significant between-group difference in EQ-5D utility scores. The cost for 1 extra person to transition out of frailty was $A15,955 (at 2011 prices). In the "very frail" subgroup (participants met >3 Cardiovascular Health Study frailty criteria), the intervention was both more effective and less costly than the control. A cost-effectiveness acceptability curve shows that the intervention would be cost-effective with 80% certainty if decision makers were willing to pay $A50,000 per extra person transitioning from frailty. In the very frail subpopulation, this reduced to $25,000. For frail older people residing in the community, a 12-month multifactorial intervention provided better value for money than usual care, particularly for the very frail, in whom it has a high probability of being cost saving, as well as effective. Trial registration: ACTRN12608000250336. Copyright © 2015 AMDA – The Society for Post-Acute and Long-Term Care

  2. Polyethylene glycol intestinal lavage in addition to usual antibiotic treatment for severe Clostridium difficile colitis: a randomised controlled pilot study.

    Science.gov (United States)

    McCreery, Greig; Jones, Philip M; Kidane, Biniam; DeMelo, Vanessa; Mele, Tina

    2017-07-31

    Clostridium difficile infections (CDI) are common, costly and potentially life threatening. Most CDI will respond to antibiotic therapy, but 3%-10% of all patients with CDI will progress to a severe, life-threatening course. Complete removal of the large bowel is indicated for severe CDI. However, the 30-day mortality following surgical intervention for severe CDI ranges from 20% to 70%. A less invasive approach using surgical faecal diversion and direct colonic lavage with polyethylene glycol (PEG) and vancomycin has demonstrated a relative mortality reduction of approximately 50%. As an alternative to these operative approaches, we propose to treat patients with bedside intestinal lavage with PEG and vancomycin instillation via nasojejunal tube, in addition to usual antibiotic management. Preliminary data collected by our research group are encouraging. We will conduct a 1-year, single-centre, pilot randomised controlled trial to study this new treatment strategy for patients with severe CDI and additional risk factors for fulminant or complicated infection. After informed consent, patients with severe-complicated CDI without immediate indication for surgery will be randomised to either usual antibiotic treatment or usual antibiotic treatment with the addition of 8 L of PEG lavage via nasojejunal tube. This pilot trial will evaluate our eligibility and enrolment rate, protocol compliance and adverse event rates and provide further data to inform a more robust sample size calculation and protocol modifications for a definitive multicentre trial design. Based on historical data, we anticipate enrolling approximately 24 patients during the 1-year pilot study period.As a pilot study, data will be reported in aggregate. Between-group differences will be assessed in a blinded fashion for evidence of harm, and to further refine our sample size calculation. This study protocol has been reviewed and approved by our local institutional review board. Results of the pilot

  3. Effectiveness of a lifestyle intervention led by female community health volunteers versus usual care in blood pressure reduction (COBIN)

    DEFF Research Database (Denmark)

    Neupane, Dinesh; McLachlan, Craig S; Mishra, Shiva Raj

    2018-01-01

    ). In the intervention group, 43 FCHVs provided home visits every 4 months for lifestyle counselling and blood pressure monitoring. Eligible participants had been involved in a previous population-based survey, were aged 25–65 years, did not have plans to migrate outside the study area, and were not severely ill......-income population. Methods We did a community-based, open-label, two-group, cluster-randomised controlled trial in Nepal. Using computer-generated codes, we randomly assigned (1:1) 14 clusters to a lifestyle intervention led by female community health volunteers (FCHVs) or usual care (control group...... participants (939 assigned to intervention; 699 assigned to control). At 1 year, 855 participants remained in the intervention group (425 were normotensive, 175 were prehypertensive, and 255 had hypertension) and 613 remained in the control group (305 were normotensive, 128 were prehypertensive, and 180 had...

  4. Properties of charmed particle nonleptonic interactions following from Δ T=1/2 rule for usual mesons and baryons

    International Nuclear Information System (INIS)

    Arbuzov, B.A.; Cartasheva, V.G.; Tikhonin, F.F.

    1978-01-01

    A version of weak interaction has been considered in the frame of the model of 4-colour quarks with integer charges. The white part of the nonleptonic Lagrangian, responsible for the weak decay of usual particles, is constructed in such a way, that the ΔT=1/2 rule be fulfilled. This requirement fixed in a certain way the set of the parameters of full weak hadronic current. Parameters obtained in such a way give a complete description of the part of the Lagrangian with c-quark. The properties of the latter one reproduce to a certain extent those of the Lagrangian obtained in the GIM model, however the Lagrangian obtained in this work contains additional terms, that cannot be derived in the GIM model

  5. Preliminary study on arsenic concentration in groundwater in usual exploited aquifer in Ho Chi Minh City (pleistocene aquifer QIm)

    International Nuclear Information System (INIS)

    Phan Thanh Tong; Nguyen Kien Chinh; Tran Thi Bich Lien; Nguyen Van Suc; Le Danh Chuan; Huynh Le Khoa

    2004-01-01

    Recent days, As in groundwater is a hot spot in some countries in Asia (e.g India, Bangladesh, Myanmar, Thailand) that was revealed through Executive Meetings of RAS/8/084. In Vietnam, some reports on groundwater quality in Red River Delta and Mekong Delta (with few random groundwater samples selected to analyse randomly) brought an opinion that groundwater in some region in Vietnam contains a quantity of As is over WHO Limit to As concentration in drinking water. This project hat been carrying out in Ho Chi Minh City in order to survey and make a preliminary assessment on As content in groundwater in shallow aquifer which is usual exploited in one of important social-economic centers of Vietnam. (author)

  6. Specialized psychosocial treatment plus treatment as usual (TAU) versus TAU for patients with cannabis use disorder and psychosis

    DEFF Research Database (Denmark)

    Hjorthøj, C R; Fohlmann, A; Larsen, Anne-Mette

    2013-01-01

    BACKGROUND: Cannabis abuse in psychotic patients is associated with rehospitalizations, reduced adherence and increased symptom severity. Previous psychosocial interventions have been ineffective in cannabis use, possibly because of low sample sizes and short interventions. We investigated whether...... adding CapOpus to treatment as usual (TAU) reduces cannabis use in patients with cannabis use disorder and psychosis. Method A total of 103 patients with psychosis and cannabis use disorder were centrally randomized to 6 months of CapOpus plus TAU (n = 52) or TAU (n = 51). CapOpus consisted mainly...... of motivational interviewing and cognitive behaviour therapy (CBT). TAU was targeted primarily at the psychotic disorder. The primary outcome was self-reported days with cannabis use in the preceding month. RESULTS: Pre-randomization cannabis use frequency was 14.9 [95% confidence interval (CI) 12.7-17.1] days...

  7. The behaviour of trace elements and radionuclides in must of grapes during fermentation and usual wine technology

    International Nuclear Information System (INIS)

    Hellmuth, K.H.; Fischer, E.

    1985-01-01

    The elements Co(II), Sr(II), Cs(I), Tl(I) and Am(III) were added as their radionuclides to the must of white grapes of one vintage and from that wine was prepared using usual wine technology. The elimination of the elements during the fermentation and as a consequence of the subsequent treatments has been determined. The decrease of the metal contents with time follows approximately an exponential function in the cases of Co, Cs, Tl and Am, whereas the Sr-content remains nearly constant. In the total balance, the following residual values were found in the final wine: Co 8.6+-0.6%, Sr 41+-4%, Cs 0.13+-0.07 resp. 0.031+-0.008%, Tl 1.3+-0.2% and Am 1.0+-0.2% of the initial value. (orig./PW) [de

  8. Neck collar, "act-as-usual" or active mobilization for whiplash injury? A randomized parallel-group trial

    DEFF Research Database (Denmark)

    Kongsted, Alice; Montvilas, Erisela Qerama; Kasch, Helge

    2007-01-01

    practitioners within 10 days after a whiplash injury and randomized to: 1) immobilization of the cervical spine in a rigid collar followed by active mobilization, 2) advice to "act-as-usual," or 3) an active mobilization program (Mechanical Diagnosis and Therapy). Follow-up was carried out after 3, 6, and 12......-extension trauma to the cervical spine. It is unclear whether this, in some cases disabling, condition can be prevented by early intervention. Active interventions have been recommended but have not been compared with information only. Methods. Participants were recruited from emergency units and general......Study Design. Randomized, parallel-group trial. Objective. To compare the effect of 3 early intervention strategies following whiplash injury. Summary of Background Data. Long-lasting pain and disability, known as chronic whiplash-associated disorder (WAD), may develop after a forced flexion...

  9. Neck collar, "act-as-usual" or active mobilization for whiplash injury? A randomized parallel-group trial

    DEFF Research Database (Denmark)

    Kongsted, Alice; Montvilas, Erisela Qerama; Kasch, Helge

    2007-01-01

    Study Design. Randomized, parallel-group trial. Objective. To compare the effect of 3 early intervention strategies following whiplash injury. Summary of Background Data. Long-lasting pain and disability, known as chronic whiplash-associated disorder (WAD), may develop after a forced flexion......-extension trauma to the cervical spine. It is unclear whether this, in some cases disabling, condition can be prevented by early intervention. Active interventions have been recommended but have not been compared with information only. Methods. Participants were recruited from emergency units and general...... practitioners within 10 days after a whiplash injury and randomized to: 1) immobilization of the cervical spine in a rigid collar followed by active mobilization, 2) advice to "act-as-usual," or 3) an active mobilization program (Mechanical Diagnosis and Therapy). Follow-up was carried out after 3, 6, and 12...

  10. [Combined pulmonary fibrosis and emphysema (CPFE)--limitation of usual lung function test and challenge at practice].

    Science.gov (United States)

    Takai, Daiya

    2014-12-01

    Spirometry and the flow-volume curve test are commonly performed lung function tests. However, a unique clinical entity occasionally shows almost normal data in these tests, and is therefore missed on screening tests. The clinical entity of combined pulmonary emphysema and pulmdoary fibrosis was recognized and documented in the 90's in Japan, the USA, and Europe. Typical emphysema shows obstructive disorders, and pulmonary fibrosis shows restrictive disorders. Thus, the combination of both should lead to a combined disorder pattern in lung function tests, but this is not the case. In 2005, Cottin reported and redefined this combination of emphysema and fibrosis of the lung as "Combined Pulmonary Fibrosis and Emphysema" (CPFE). The patients are typically heavily smoking males who show an almost normal lung function. The upper lobe of these patients usually shows severe emphysema, which contributes to a static volume and a late phase in the forced volume test. On the other hand their lower lobe shows fibrotic change. The fibrotic portion contributes to early phase flow in the flow-volume curve. These mechanisms are a reason for the normal pattern appearance in lung function tests in CPFE patients. As a matter of course, these patients have damaged upper and lower lobes: their diffusing capacity of the lung shows a low performance, their saturation of blood hemoglobin decreases soon after light exercise, and their KL-6 (a blood marker of pulmonary fibrosis) usually shows a high value. They are considered a high risk group regarding complications of post-surgical treatment. Thus, when medical technologists identify suspicious cases, they should advise doctors to add diffusing capacity and KL-6 tests. (Review).

  11. Skin care education and individual counselling versus treatment as usual in healthcare workers with hand eczema: randomised clinical trial.

    Science.gov (United States)

    Ibler, Kristina Sophie; Jemec, Gregor B E; Diepgen, Thomas L; Gluud, Christian; Lindschou Hansen, Jane; Winkel, Per; Thomsen, Simon Francis; Agner, Tove

    2012-12-12

    To evaluate the effect of a secondary prevention programme with education on skin care and individual counselling versus treatment as usual in healthcare workers with hand eczema. Randomised, observer blinded parallel group superiority clinical trial. Three hospitals in Denmark. 255 healthcare workers with self reported hand eczema within the past year randomised centrally and stratified by profession, severity of eczema, and hospital. 123 were allocated to the intervention group and 132 to the control group. Education in skin care and individual counselling based on patch and prick testing and assessment of work and domestic related exposures. The control was treatment as usual. The primary outcome was clinical severity of disease at five month follow-up measured by scores on the hand eczema severity index. The secondary outcomes were scores on the dermatology life quality index, self evaluated severity of hand eczema, skin protective behaviours, and knowledge of hand eczema from onset to follow-up. Follow-up data were available for 247 of 255 participants (97%). At follow-up, the mean score on the hand eczema severity index was significantly lower (improved) in the intervention group than control group: difference of means, unadjusted -3.56 (95% confidence interval -4.92 to -2.14); adjusted -3.47 (-4.80 to -2.14), both Pgroup at follow-up: difference of means: unadjusted -0.78, non-parametric test P=0.003; adjusted -0.92, -1.48 to -0.37). Self evaluated severity and skin protective behaviour by hand washings and wearing of protective gloves were also statistically significantly better in the intervention group, whereas this was not the case for knowledge of hand eczema. A secondary prevention programme for hand eczema improved severity and quality of life and had a positive effect on self evaluated severity and skin protective behaviour by hand washings and wearing of protective gloves. ClinicalTrials.gov NCT01012453.

  12. Semi-Individualized Homeopathy Add-On Versus Usual Care Only for Premenstrual Disorders: A Randomized, Controlled Feasibility Study.

    Science.gov (United States)

    Klein-Laansma, Christien T; Jong, Mats; von Hagens, Cornelia; Jansen, Jean Pierre C H; van Wietmarschen, Herman; Jong, Miek C

    2018-03-22

    Premenstrual syndrome and premenstrual dysphoric disorder (PMS/PMDD) bother a substantial number of women. Homeopathy seems a promising treatment, but it needs investigation using reliable study designs. The feasibility of organizing an international randomized pragmatic trial on a homeopathic add-on treatment (usual care [UC] + HT) compared with UC alone was evaluated. A multicenter, randomized, controlled pragmatic trial with parallel groups. The study was organized in general and private homeopathic practices in the Netherlands and Sweden and in an outpatient university clinic in Germany. Women diagnosed as having PMS/PMDD, based on prospective daily rating by the daily record of severity of problems (DRSP) during a period of 2 months, were included and randomized. Women were to receive UC + HT or UC for 4 months. Homeopathic medicine selection was according to a previously tested prognostic questionnaire and electronic algorithm. Usual care was as provided by the women's general practitioner according to their preferences. Before and after treatment, the women completed diaries (DRSP), the measure yourself concerns and well-being, and other questionnaires. Intention-to-treat (ITT) and per protocol (PP) analyses were performed. In Germany, the study could not proceed because of legal limitations. In Sweden, recruitment proved extremely difficult. In the Netherlands and Sweden, 60 women were randomized (UC + HT: 28; UC: 32), data of 47/46 women were analyzed (ITT/PP). After 4 months, relative mean change of DRSP scores in the UC + HT group was significantly better than in the UC group (p = 0.03). With respect to recruitment and different legal status, it does not seem feasible to perform a larger, international, pragmatic randomized trial on (semi-)individualized homeopathy for PMS/PMDD. Since the added value of HT compared with UC was demonstrated by significant differences in symptom score changes, further studies are warranted.

  13. Associations between usual school lunch attendance and eating habits and sedentary behaviour in French children and adolescents.

    Science.gov (United States)

    Dubuisson, C; Lioret, S; Dufour, A; Volatier, J L; Lafay, L; Turck, D

    2012-12-01

    Our objective was to investigate whether school lunch attendance was associated with overall eating habits and sedentary behaviour in a French sample of children and adolescents. Data for the study were taken from the second French cross-sectional dietary survey (INCA2-2006-07). In total, 1413 school children aged 3-17 years old were classified according to their school type and their usual school lunch attendance. Eating habits included meal regularity, dietary diversity, purchase in vending machine, snacking habits and frequency of eating in fast-foods. Two composite indices of eating habits were derived from multiple correspondence analyses. Sedentary behaviour was assessed by the average daily screen times for TV and computer. The association between school lunch attendance and each variable was tested. Multivariate association between school lunch attendance and the composite indices of eating habits and sedentary behaviours was studied. In all, 69.0% (CI(95%): 64.2-73.9) of secondary school children and 63.0% (CI(95%): 58.5-67.5) of pre- and elementary school children usually attended school lunch at least once a week. Pre- and elementary school children attending school lunches showed a higher dietary diversity score (P=0.02) and ate morning snacks more frequently (P=0.02). In secondary school children, attending school canteen was related to a lower rate of skipping breakfast (P=0.04) and main meals (P=0.01). In all school children, school lunch attendance was simultaneously associated with healthier overall eating habits and less sedentary behaviour. In France, children attending school canteens seem to have healthier eating habits and display less sedentary behaviour, independently of their socio-economic and demographic background.

  14. Cost-effectiveness of cognitive behaviour therapy versus talking and usual care for depressed older people in primary care

    Directory of Open Access Journals (Sweden)

    Leurent Baptiste E

    2011-02-01

    Full Text Available Abstract Background Whilst evidence suggests cognitive behaviour therapy (CBT may be effective for depressed older people in a primary care setting, few studies have examined its cost-effectiveness. The aim of this study was to compare the cost-effectiveness of cognitive behaviour therapy (CBT, a talking control (TC and treatment as usual (TAU, delivered in a primary care setting, for older people with depression. Methods Cost data generated from a single blind randomised controlled trial of 204 people aged 65 years or more were offered only Treatment as Usual, or TAU plus up to twelve sessions of CBT or a talking control is presented. The Beck Depression Inventory II (BDI-II was the main outcome measure for depression. Direct treatment costs were compared with reductions in depression scores. Cost-effectiveness analysis was conducted using non-parametric bootstrapping. The primary analysis focussed on the cost-effectiveness of CBT compared with TAU at 10 months follow up. Results Complete cost data were available for 198 patients at 4 and 10 month follow up. There were no significant differences between groups in baseline costs. The majority of health service contacts at follow up were made with general practitioners. Fewer contacts with mental health services were recorded in patients allocated to CBT, though these differences were not significant. Overall total per patient costs (including intervention costs were significantly higher in the CBT group compared with the TAU group at 10 month follow up (difference £427, 95% CI: £56 - £787, p Conclusions CBT is significantly more costly than TAU alone or TAU plus TC, but more clinically effective. Based on current estimates, CBT is likely to be recommended as a cost-effective treatment option for this patient group if the value placed on a unit reduction in BDI-II is greater than £115. Trial Registration isrctn.org Identifier: ISRCTN18271323

  15. Absence of the predisposing factors and signs and symptoms usually associated with overreaching and overtraining in physical fitness centers

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    Carolina Ackel-D'Elia

    2010-01-01

    Full Text Available OBJECTIVE: The aim of this study was to evaluate the occurrence of the well-known predisposing factors and signs and symptoms usually associated with either overreaching or overtraining syndrome in physical fitness centers in São Paulo City, Brazil. METHOD: A questionnaire consisting of 13 question groups pertaining to either predisposing factors (1-7 or signs and symptoms (8-13 was given to 413 subjects. The general training schedule of the volunteers was characterized by workout sessions of 2.18 ± 0.04 h for a total of 11.0 ± 0.3 h/week for 33 ± 2 months independent of the type of exercise performed (walking, running, spinning, bodybuilding and stretching. A mean score was calculated ranging from 1 (completely absent to 5 (severe for each question group. A low occurrence was considered to be a question group score lower than 4, which was observed in all 13 question groups. RESULTS: The psychological evaluation by POMS Mood State Questionnaire indicated a normal non-inverted iceberg. The hematological parameters, creatine kinase activity, cortisol, total testosterone and free testosterone concentrations were within the normal ranges for the majority of the volunteers selected for this analysis (n = 60. CONCLUSION: According to the questionnaire score analysis, no predisposing factors or signs and symptoms usually associated with either overreaching or overtraining were detected among the members of physical fitness centers in São Paulo City, Brazil. This observation was corroborated by the absence of any significant hematological or stress hormone level alterations in blood analyses of the majority of the selected volunteers (n = 60.

  16. Complicações obstétricas em gestações com feto portador de anomalia incompatível com a sobrevida neonatal Complicaciones obstétricas en gestaciones con feto portador de anomalía incompatible con la sobrevivencia neonatal Obstetric complications in pregnancies with fetal anomalies incompatible with neonatal survival

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    Danila Cristina Paquier Sala

    2010-10-01

    Full Text Available OBJETIVO: Descrever as complicações obstétricas mais comuns encontradas nos períodos gestacional, parto e puerpério imediato de gestantes com fetos portadores de anomalias incompatíveis com a vida. MÉTODOS: Estudo descritivo, onde avaliou-se 78 prontuários de pacientes atendidas no pré-natal da Disciplina de Medicina Fetal da Universidade Federal de São Paulo que tiveram partos nessa mesma instituição, entre 2000 e 2006. RESULTADOS: As principais complicações obstétricas identificadas foram:variação do volume de líquido amniótico em 68%; abortamento, parto pré-termo e a gravidez prolongada estiveram presentes em 6,4%, 55,1% e 3,8% das gestações, respectivamente; óbito fetal intra-uterino em 17,9%; descolamento prematuro da placenta ocorreu em 6,4% e histerectomia em 2,6%. CONCLUSÃO: Estes resultados sugerem aumento de risco materno em gestações com fetos portadores de anomalias graves, fato que demonstra necessidade de avaliação especializada caso a caso.OBJETIVO: Describir las complicaciones obstétricas más comunes encontradas en los períodos de gestación, parto y puerperio inmediato de embarazadas con fetos portadores de anomalías incompatibles con la vida. MÉTODOS: Se trata de un estudio descriptivo, que evaluó 78 fichas médicas de pacientes atendidos en el prenatal de la Disciplina de Medicina Fetal de la Universidad Federal de Sao Paulo que tuvieron partos en esa misma institución, entre 2000 y 2006. RESULTADOS: Las principales complicaciones obstétricas identificadas fueron: variación del volumen de líquido amniótico en 68%; abortamiento, parto pre-término y embarazo prolongado estuvieron presentes en 6,4%, 55,1% y 3,8% de las gestaciones, respectivamente; muerte fetal intra-uterina en 17,9%; desprendimiento prematuro de la placenta ocurrió en 6,4% e histerectomía en 2,6%. CONCLUSIÓN: Éstos resultados sugieren un aumento del riesgo materno en gestaciones con fetos portadores de anomal

  17. Complicaciones maternas y mortalidad perinatal en el Síndrome de Hellp: Registro multicéntrtico en unidades de cuidados intensivos del área Buenos Aires Maternal morbidity and perinatal mortality in HELLP syndrome. Multicentric studies in intensive care units in Buenos Aires area

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    Eduardo Malvino

    2005-03-01

    Full Text Available Se analizaron en forma retrospectiva las características clínicas, complicaciones, gravedad, y sobrevivencia materna y fetal, en un grupo de gestantes con síndrome HELLP ( Hemolysis , Elevated Liver enzyme levels, Low Platelet count que requirieron admisión en cuatro unidades de cuidados intensivos del área metropolitana Buenos Aires, Argentina. Durante el período comprendido entre marzo de 1997 y marzo de 2003 se evaluaron 62 pacientes en la segunda mitad del embarazo o el puerperio inmediato que cumplían criterios diagnósticos de hipertensión inducida por el embarazo, asociado a plaquetopenia 70 UI/l, láctico deshidrogenasa >600 UI/l, bilirrubina total >1.2 mg / dl , y/o frotis de sangre periférica con signos de hemólisis. La edad promedio fue 28 ± 8 años; número de gestas promedio 2.7 ± 2.3; edad gestacional media 33 ± 4 semanas. Según el grado de plaquetopenia, 23 casos pertenecieron a la clase 1, 29 a la clase 2 y el resto a la clase 3 de la clasificación de Martin . Hubo 16 formas eclámpticas. El recuento plaquetario promedio fue 67 604 ± 31 535/ mm3 ; TGO 271 ± 297 UI/l; TGP 209 ± 178 UI/l; LDH 1 444 ± 1 295 UI/l; creatininemia 1.1 ± 0.8 mg / dl. Cuarenta y una pacientes cursaron con diverso grado de deterioro del filtrado glomerular, con requerimiento de tratamiento hemodialítico y plasmaféresis en un caso. Se presentó insuficiencia respiratoria vinculada a síndrome de distrés respiratorio del adulto en cuatro enfermas. Todas las puérperas sobrevivieron y se comprobaron cuatro muertes perinatales. En la población estudiada, se observó baja prevalencia de complicaciones graves, óptima sobrevivencia materna y baja mortalidad perinatal.We analized the clinical characteristics, complications, severity, and maternal and fetal survival of patients suffering from HELLP syndrome ( Hemolysis , Elevated Liver enzymes level, Low Platelet count requiring admission to the intensive care unit in four hospitals from

  18. En el sellado del catéter venoso central en hemodiálisis, ¿presenta el uso de citrato respecto al uso de heparina menos complicaciones de infección? Una revisión de la literatura

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    Mateu Nadal Servera

    Full Text Available Resumen Introducción: La heparina es el fármaco anticoagulante de elección y de uso habitual en los servicios de hemodiálisis, en el procedimiento de permeabilización de los catéteres venosos centrales, aunque su uso no está exento de riesgos como la hemorragia. La infección asociada al catéter, bien por colonización del catéter o por bacteriemia, es el evento más importante y la segunda causa de mortalidad tras la enfermedad cardiovascular en el paciente en hemodiálisis. En este sentido, el uso del citrato se está presentando como una alternativa para el sellado de los catéteres venosos centrales, dado que tiene propiedades tanto anticoagulantes locales como antimicrobianas y podría ser más eficiente en la prevención o la reducción de la infección asociada al catéter. Objetivos: Identificar qué anticoagulante de uso en el sellado del catéter venoso central, la heparina o el citrato, presenta menos complicaciones de bacteriemia asociada al catéter y de colonización del catéter; Material y Método: se realizó una búsqueda bibliográfica a través del metabuscador EBSCOhost (Academic Search Premier, CINAHL y las bases de datos PubMed, IME, Ibecs, LILACS, CUIDEN, Scopus y Cochrane Library, con la selección final de 15 documentos tras la aplicación de los límites de búsqueda, la eliminación de duplicados y la aplicación de los criterios de inclusión/exclusión. Los resultados más relevantes y actuales disponibles en la literatura científica presentaron cierta variabilidad, tanto en las concentraciones de anticoagulante como en la incidencia de infección. Resultados y Discusión: La numerosa evidencia sobre la bacteriemia asociada al catéter, tanto en relación con la concentración como en la combinación del anticoagulante de sellado, indica que el citrato 4% podría reducir la incidencia de bacteriemia, aunque el citrato asociado a antimicrobianos es más efectivo en la prevención de ésta respecto a la

  19. Factores de riesgo para complicaciones en el periodo de recuperación post anestésica en el paciente anciano Fatores de risco para complicações no período de recuperação pós anestésica no paciente idoso Risk factors for complications in the post anesthesia period in elderly patients

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    Isabel Yovana Quispe Mendoza

    2010-11-01

    Full Text Available Objetivos. Identificar los factores de riesgo para complicaciones en el periodo de recuperación post anestésica en el paciente anciano. Metodología. Estudio descriptivo retrospectivo. Los datos fueron recolectados de las historias clínicas de pacientes ancianos. Resultados. Se estudiaron 110 pacientes que tuvieron este perfil: sexo masculino (56.4%, hipertensos (32.7% y fueron clasificados en ASA II (60.0%. En cuanto al intraoperatorio: fueron sometidos a cirugía abdominal (53.6%, les administraron anestesia general (50.9%, estuvieron durante la cirugía posición de decúbito dorsal (81.8% y el período intraoperatorio fue inferior a tres horas (62.7%. Las complicaciones más frecuentes fueron: hipotermia (55.5%, dolor (43.6% y aumento de la presión arterial (36.4%. Conclusión. Se evidenció la importancia de la visita preoperatoria con la finalidad de evaluar los factores de riesgo que puedan influenciar en el procedimiento quirúrgico.Objetivos. Identificar os fatores de risco para complicações no período de recuperação pós anestésica no paciente idoso. Metodologia. Estudo descritivo retrospectivo. Os dados foram coletados das histórias clínicas de pacientes idosos. Resultados. Estudaram-se 110 pacientes que tiveram este perfil: sexo masculino (56.4%, hipertensos (32.7% e foram classificados em ASA II (60.0%. Quanto ao intra-operatório: foram submetidos a cirurgia abdominal (53.6%, administraram-lhes anestesia geral (50.9%, estiveram durante a cirurgia posição de decúbito dorsal (81.8% e o período intra-operatório foi inferior a três horas (62.7%. As complicações mais freqüentes foram: hipotermia (55.5%, dor (43.6% e aumento da pressão arterial (36.4%. Conclusão. Evidenciou-se a importância da visita pré-operatória com a finalidade de avaliar os fatores de risco que possam influenciar no procedimento cirúrgico.Objective. To identify the risk for complications in the post anesthesia recovery period in elderly

  20. Autoconocimiento, monitorización y complicaciones de la diabetes en la jornada No más ciegos por diabetes en Antioquia, 2005 Self-knowledge, control and complications of diabetes at no more blind by diabetes session in Antioquia, 2005

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    Guillermo Latorre Sierra

    2007-03-01

    Full Text Available INTRODUCCIÓN: una sólida educación a los pacientes en temas relacionados con la diabetes y la monitorización de la glucosa, se han asociado con mejor control metabólico, mayor entendimiento de la enfermedad, auto confianza y mejor cuidado clínico. MATERIALES Y MÉTODOS: estudio de corte transversal, en la jornada No más ciegos por diabetes en Antioquia 2005. Se diligenció un cuestionario indagando acerca de la monitorización, tipo de diabetes, tratamiento y complicaciones; se midieron la glucometría, el peso, la talla y el perímetro abdominal. RESULTADOS: se incluyeron 210 pacientes, de los cuales 36,6% no saben que tipo de diabetes tienen, 59,7% no saben que es la hemoglobina glicosilada y 25,8% saben que este examen debe realizarse cada 3 a 4 meses, sin embargo, solo se le había realizado a siete pacientes (3,3% con la frecuencia ideal. El 36,4% tienen glucómetro y 60,6% de los pacientes saben que se deben realizarse una evaluación oftalmológica anual. En los pacientes con Diabetes Mellitus tipo 2 el 26,2% tuvo glucometrías postprandial menores de 140 mg/dl. Las complicaciones informadas con mayor frecuencia fueron el compromiso renal y descompensación aguda en los Diabéticos tipo 1, la dislipidemia y la neuropatía periférica en los diabéticos tipo 2. INTRODUCTION: A better knowledge about diabetes by patients has been associated with better understanding of the disease, self esteem and improved clinical care and metabolic control. MATERIAL AND METHODS: It is a cohort study, made during the “No more blind by Diabetes” session, 2005. The study population fills out the form with questions about the blood glucose control, type of diabetes and treatment. Also a measure of blood glucose, height, weight, and abdominal circumference was made. RESULTS: 210 patients were included, 36.6% did not know which type of diabetes they have, 59.7% did not know what glycosylated hemoglobin is, 25.8% know that the frequency to evaluated

  1. Complicações e intercorrências associadas ao edema de braço nos três primeiros meses pós mastectomia Complicaciones e intercurrencias asociadas al edema de brazo en los tres primeros meses después de la mastectomía Complications and intercurrences associated with arm edema in the first three months following mastectomy

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    Marislei Sanches Panobianco

    2002-07-01

    Full Text Available Este estudo buscou identificar complicações, intercorrências e aparecimento de edema pós cirurgia por câncer de mama, e fatores que poderiam estar predispondo ao linfedema do braço do lado operado. É um estudo descritivo, prospectivo e de abordagem quantitativa. A população constou de 17 mulheres submetidas à cirurgia unilateral por câncer de mama, em um hospital-escola. A coleta de dados deu-se por meio do acompanhamento semanal dos sujeitos, nos três meses pós-cirurgia. O edema apareceu em 11 mulheres, sendo, em nove, de grau leve, e, em duas de grau moderado. É importante lembrar que o edema leve poderá tornar-se grave se não tratado, devidamente. Observou-se, entre as mulheres com edema, complicações, intercorrências, e outras variáveis. Os resultados revelam a importância do acompanhamento de enfermagem no pós-operatório, e a necessidade de um melhor preparo dos profissionais para a orientação de pacientes, com o objetivo de prevenir o linfedema.Este estudio buscó identificar complicaciones, intercurrencias y el aparecimiento del edema después de la cirugía por cáncer de mama y factores que pueden estar facilitando el aparecimiento del linfodema del brazo del lado operado. Es un estudio descriptivo, prospectivo y de abordaje cuantitativa. La población fue formada por 17 mujeres sometidas a cirugía unilateral por cáncer de mama en un hospital escuela. La recolección de datos ocurrió a través del seguimiento semanal de los sujetos, en los tres meses después de la cirugía. El edema apareció en 11 mujeres, siendo en nueve de grado leve y en dos de grado moderado. Es importante recordar que el edema leve podrá tornarse grave si no es tratado. Se observó entre las mujeres con edema, complicaciones, intercurrencias y otras variables. Los resultados revelan la importancia del seguimiento de enfermería en la fase posquirúrgica y la necesidad de una mejor preparación de los profesionales para la orientaci

  2. Incidência de complicações pulmonares na cirurgia de revascularização do miocárdio Incidencia de complicaciones pulmonares en la cirugía de revascularización del miocardio Incidence of pulmonary complications in myocardial revascularization

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    Leila D. N Ortiz

    2010-10-01

    tanto, las complicaciones pulmonares después del abordaje quirúrgico aun son frecuentes, predisponiendo al paciente a un mayor tiempo de internación o al óbito. OBJETIVO: Describir la incidencia de complicaciones pulmonares y identificar su asociación con tiempos de circulación extracorporal (CEC; cirugía e isquemia; número de injertos; localización y tiempo de drenajes después de cirugía de revascularización del miocardio (CRM. MÉTODOS: En esta cohorte contemporánea, fueron estudiados 202 pacientes en hospital universitario de referencia para cardiología en el sur del Brasil, sometidos a la CRM electiva con puente safena y arteria mamaria interna con CEC, en el período de abril/2006 a noviembre/2007. Los desenlaces considerados fueron: tiempo de ventilación mecánica; surgimiento de neumonía; atelectasia; derrame pleural; hora de la retirada y localización de los drenajes; y tiempo de internación. RESULTADOS: Se observó algún tipo de complicación pulmonar en 90 de los 202 pacientes. La frecuencia de derrame pleural fue de 84% y la de atelectasia fue de 65%. Presentaron asociación con complicaciones pulmonares los tiempos de CEC (p = 0,003, quirúrgico (p = 0,040e isquemia (p = 0,001; el tiempo de permanencia de drenajes (p = 0,050 y la localización pleural de los drenajes (p = 0,033, además de edad (p = 0,001, fracción de eyección (p = 0,010, diagnóstico de asma (p = 0,047 y examen radiológico de tórax pre-operatorio anormal (p = 0,029. CONCLUSIÓN: Variables relacionadas a la complejidad del acto quirúrgico y comorbilidades pre-existentes están asociadas a una alta incidencia de complicaciones pulmonares en el post-operatorio. Esos datos refuerzan la importancia de la evaluación clínica peri-operatoria para detección precoz de complicación respiratoria después de CRM.BACKGROUND: Despite the increasingly careful attempts to reduce perioperative risks, pulmonary complications following surgery are still very common, leading to

  3. Assessing usual dietary intake in complex sample design surveys: the National Dietary Survey Evaluación del consumo alimentario usual en investigaciones con muestras complejas: pesquisa nacional de alimentación Avaliação do consumo alimentar usual em pesquisas com amostras complexas: Inquérito Nacional de Alimentação

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    Washington Leite Junger

    2013-02-01

    Full Text Available The National Cancer Institute (NCI method allows the distributions of usual intake of nutrients and foods to be estimated. This method can be used in complex surveys. However, the user must perform additional calculations, such as balanced repeated replication (BRR, in order to obtain standard errors and confidence intervals for the percentiles and mean from the distribution of usual intake. The objective is to highlight adaptations of the NCI method using data from the National Dietary Survey. The application of the NCI method was exemplified analyzing the total energy (kcal and fruit (g intake, comparing estimations of mean and standard deviation that were based on the complex design of the Brazilian survey with those assuming simple random sample. Although means point estimates were similar, estimates of standard error using the complex design increased by up to 60% compared to simple random sample. Thus, for valid estimates of food and energy intake for the population, all of the sampling characteristics of the surveys should be taken into account because when these characteristics are neglected, statistical analysis may produce underestimated standard errors that would compromise the results and the conclusions of the survey.El objetivo del estudio fue indicar una adaptación del método del Instituto Nacional del Cáncer (NCI, utilizándose datos de la pesquisa nacional de alimentación. Ese método estima la distribución del consumo usual de nutrientes y alimentos y puede ser aplicado en estudios con muestra compleja. Mientras, son necesarios cálculos adicionales, tales como la replicación repetida balanceada, a fin de obtener los errores estándar e intervalos de confianza para los percentiles y el promedio de la distribución de consumo usual. La aplicación de este método fue ejemplificado analizando el total de energía (Kcal y frutas (gr, comparando las estimaciones de los promedios y sus respectivos errores estándar obtenidos

  4. Transplante cardíaco: complicações apresentadas por pacientes durante a internação Trasplante de corazón: complicaciones que presentan los pacientes durante la hospitalización Heart Transplantation: complications presented by patients during the hospitalization

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    Elaine Araújo da Silva

    2012-12-01

    Full Text Available Com o avanço da ciência, a insuficiência cardíaca tem como possibilidade de intervenção o transplante cardíaco. Este trabalho teve como objetivos traçar o perfil demográfico dos pacientes submetidos ao transplante cardíaco e identificar as complicações apresentadas durante a internação. Trata-se de um estudo descritivo, quantitativo, realizado com 44 prontuários de pacientes submetidos a transplante de junho/2006 a julho/2009 em um Hospital Universitário de Belo Horizonte, Minas Gerais, Brasil. O projeto atendeu às recomendações da Resolução 196/96. Pelos resultados, a maioria dos pacientes era do sexo masculino, casada, escolaridade de nível fundamental e idade média de 45,2 anos. A miocardiopatia chagásica foi a principal causa de insuficiência cardíaca. As complicações predominantes foram alteração da glicemia, insuficiência renal e infecções. A taxa de mortalidade na internação foi de 20,4%. Além das complicações biológicas só foram registradas ansiedade e depressão. São necessárias pesquisas sobre o tema nos âmbitos psicossociais e espirituais, contribuindo para o desenvolvimento científico.Hoy día, con los avances de la medicina y de la tecnología para el tratamiento de la insuficiencia cardiaca irreversible, se ha utilizado como última intervención el trasplante cardíaco. Este trabajo se desarrolló con los objetivos de delinear el perfil demográfico de los pacientes sometidos a trasplante cardíaco e identificar las complicaciones presentadas por ellos después del trasplante de corazón. Estudio descriptivo y cuantitativo, realizado en conjunto con los registros de 44 pacientes sometidos a trasplante de corazón desde Jun/2006 hasta Jul/2009, en un Hospital Universitario de Belo Horizonte, Minas Gerais, Brasil. El proyecto cumplió con las recomendaciones de la Resolución 196/96. Los resultados mostraron que la mayoría de los pacientes eran del sexo masculino, casados, con educaci

  5. A randomized controlled trial of adjunctive family therapy and treatment as usual following inpatient treatment for anorexia nervosa adolescents.

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    Nathalie Godart

    Full Text Available UNLABELLED: Research on treatments in anorexia nervosa (AN is scarce. Although most of the therapeutic programs used in 'real world practice' in AN treatment resort to multidisciplinary approaches, they have rarely been evaluated. OBJECTIVE: To compare two multidimensional post-hospitalization outpatients treatment programs for adolescents with severe AN: Treatment as Usual (TAU versus this treatment plus family therapy (TAU+FT. METHOD: Sixty female AN adolescents, aged 13 to 19 years, were included in a randomized parallel controlled trial conducted from 1999 to 2002 for the recruitment, and until 2004 for the 18 months follow-up. Allocation to one of the two treatment groups (30 in each arm was randomised. The TAU program included sessions for the patient alone as well as sessions with a psychiatrist for the patient and her parents. The TAU+FT program was identical to the usual one but also included family therapy sessions targeting intra-familial dynamics, but not eating disorder symptoms. The main Outcome Measure was the Morgan and Russell outcome category (Good or Intermediate versus Poor outcome. Secondary outcome indicators included AN symptoms or their consequences (eating symptoms, body mass index, amenorrhea, number of hospitalizations in the course of follow-up, social adjustment. The evaluators, but not participants, were blind to randomization. RESULTS: At 18 months follow-up, we found a significant group effect for the Morgan and Russell outcome category in favor of the program with family therapy (Intention-to-treat: TAU+FT :12/30 (40%; TAU : 5/29 (17.2% p = 0.05; Per Protocol analysis: respectively 12/26 (46.2%; 4/27 (14.8%, p = 0.01. Similar group effects were observed in terms of achievement of a healthy weight (i.e., BMI≥10(th percentile and menstrual status. CONCLUSIONS: Adding family therapy sessions, focusing on intra-familial dynamics rather than eating symptomatology, to a multidimensional program improves

  6. Incidence of vascular complications in patients submitted to percutaneous transluminal coronary angioplasty by transradial and transfemoral arterial approach Incidencia de complicaciones vasculares en pacientes sometidos a angioplastía coronaria transluminal percutánea por vía arterial transradial y transfemoral Incidência de complicações vasculares em pacientes submetidos a angioplastia coronariana transluminal percutânea por via arterial transradial e transfemoral

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    Marinez Kellermann Armendaris

    2008-03-01

    Full Text Available OBJECTIVE: To describe the vascular complications of transradial and transfemoral artery punctures in patients submitted to percutaneous transluminal coronary angioplasty (PTCA. METHODS: Prospective cohort study including patients submitted to PTCA. An interview was performed and an instrument applied to collect risk factors/predictors of complications. After the procedure, a physical examination was performed, vital signs were measured and the puncture site was assessed. RESULTS: 199 patients were included, age 64±10 years. Complications found for the radial and femoral approach were respectively: ecchymosis (18.29%, (17.14%; bruising (17.66%, (14.27%; urinary retention (2.43%, (25.71%; loss of vessel permeability (8.53%, (0%. CONCLUSION: The complications found were considered minor or secondary, depending on the classification found in literature. A higher rate of vascular complications related to transradial artery punctures compared to the interventions performed by transfemoral approach.OBJETIVO: Describir complicaciones vasculares relacionadas a punciones arteriales transradial y transfemoral en pacientes sometidos a angioplastía coronaria transluminal percutánea (ACTP. MÉTODOS: Se trata de un estudio de cohorte prospectivo realizado con pacientes sometidos a ACTP. Se llevó a cabo una entrevista y aplicó un instrumento para obtener factores de riesgo/predictores. Fue realizado un examen físico, medición de signos vitales y se evaluó el lugar de punción. RESULTADOS: Fueron incluidos 199 pacientes, edad 64±10 años. Las complicaciones encontradas para vía radial y femoral respectivamente, fueron: esquimosis (18,29%, (17,14%; hematoma (17,66%, (14,27%; retención urinaria (2,43%, (25,71%; pérdida de permeabilidad de vaso (8,53%, (0%. CONCLUSIÓN: Las complicaciones fueron consideradas menores o secundarias conforme clasificación literaria. Existe una mayor incidencia de complicaciones vasculares relacionadas a punciones

  7. Intervenções de enfermagem nas complicações mais freqüentes durante a sessão de hemodiálise: revisão da literatura Intervenciones de enfermería en las complicaciones más frecuentes durante la sesión de hemodialisis: revisión de la literatura Nursing interventions for the most frequent complications during hemodialysis procedure: literature review

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    Cristiano Dias Nascimento

    2005-12-01

    Full Text Available O procedimento hemodialítico tem complicações potenciais e o enfermeiro deve estar apto a intervir em tais complicações. Considerando este contexto, este artigo tem como objetivo descrever as complicações mais freqüentes relacionadas à hemodiálise e as intervenções de enfermagem a elas relacionadas. Esta revisão de literatura consiste em pesquisa as Bases de Dados, LILACS, BEDENF E MEDLINE, utilizando descritores pertinentes. Os resultados demonstraram que as complicações que ocorrem com maior freqüência são: hipotensão, hipertensão, cãibras musculares, náusea e vômito, cefaléia, dor torácica e lombar, prurido, febre e calafrios. Concluiu-se que o papel do enfermeiro é essencial para a monitorização, detecção e intervenção em tais complicações e que este é um diferencial para a obtenção de segurança e qualidade no procedimento hemodialítico. No entanto, existe a necessidade de realização de mais pesquisas na área de enfermagem para melhor definir a atuação do enfermeiro.Lo procedimiento de hemodialisis tiene complicaciones potenciales y los enfermeros deben estar aptos a intervenir en ellos. Al considerar esto contexto, lo artículo objectiva describir las complicaciones más frecuentes relacionadas a la hemodialisis así como las intervenciones de enfermería. Esta revisión bibliografica ha consistido de busqueda a las basis de datos LILACS, DBENF y MEDLINE usandose descriptores pertinentes. Resultados han demonstrado que las mayores complicaciones son: hipotensión, hipertensión, distres musculares, nausea, vomitos, cefalea, dolor toracica y lumbar, prurido, fiebre y calafrios. Se ha concluido que el papel del enfermero es esencial para la monitorización, identificación y intervención en estas complicaciones y que esto papel tanbien es uno diferencial para obterse la calidad en lo procedimiento hemodialitico. Entremientes, hay una necessidad de realizarse más pesquisas en la area de enfermer

  8. Trends in the Types of Usual Sources of Care: A Shift from People to Places or Nothing at All.

    Science.gov (United States)

    Liaw, Winston; Jetty, Anuradha; Petterson, Stephen; Bazemore, Andrew; Green, Larry

    2017-08-31

    (1) To examine usual source of care (USC) trends across four categories (No USC, Person USC, Person, in Facility USC, and Facility USC), and (2) to determine whether USC types are associated with emergency department (ED) visits and hospital admissions. 1996-2014 Medical Expenditure Panel Surveys. We stratified each USC category, by age, region, gender, poverty, insurance, race/ethnicity, and education and used regression to determine the characteristics associated with USC types, ED visits, and hospital admissions. Those with No USC and Facility USCs increased 10 and 18 percent, respectively, while those with Person USCs decreased by 43 percent. Compared to those in the lowest income bracket, those in the highest income bracket were less likely to have a Facility USC. Among those with low incomes, individuals with No USC, Person, in Facility, and Facility USCs were more likely to have ED visits than those with Person USCs. A growing number are reporting facilities as their USCs or none at all. The impact of these trends is uncertain, although we found that some USC types are associated with ED visits and hospital admissions. Tracking USCs will be crucial to measuring progress toward enhanced care efficiency. © Health Research and Educational Trust.

  9. Preventive Dental Checkups and Their Association With Access to Usual Source of Care Among Rural and Urban Adult Residents.

    Science.gov (United States)

    Khan, Aishah; Thapa, Janani R; Zhang, Donglan

    2017-09-01

    This study aimed to assess the relationship between rural or urban residence and having a usual source of care (USC), and the utilization of preventive dental checkups among adults. Cross-sectional analysis was conducted using data from the Medical Expenditure Panel Survey 2012. We performed a logit regression on the relationship between rural and urban residence, having a USC, and having at least 1 dental checkup in the past year, adjusting for sociodemographic characteristics and health status. After controlling for covariates, rural adult residents had significantly lower odds of having at least 1 dental checkup per year compared to their urban counterparts (odds ratio [OR] = 0.73, 95% confidence interval [CI]: 0.62-0.86, P rural and urban residents, having a USC was significantly associated with an 11% (95% CI = 9%-13%) increase in the probability of having a preventive dental checkup within a year. Individuals with a USC were more likely to obtain a preventive dental visit, with similar effects in rural and urban settings. We attributed the lower odds of having a checkup in rural regions to the lower density of oral health care providers in these areas. Integration of rural oral health care into primary care may help mitigate the challenges due to a shortage of oral health care providers in rural areas. © 2017 National Rural Health Association.

  10. Usual interstitial pneumonia and nonspecific interstitial pneumonia: Correlation between CT findings at the site of biopsy with pathological diagnoses

    Energy Technology Data Exchange (ETDEWEB)

    Sumikawa, Hiromitsu, E-mail: h-sumikawa@radiol.med.osaka-u.ac.jp [Department of Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0825 (Japan); Johkoh, Takeshi [Department of Radiology, Kinki Central Hospital of Mutual Aid Association of Public Health Teachers, 3-1 Kurumazuka, Itami, Hyougo 664-8533 (Japan); Fujimoto, Kiminori [Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011 (Japan); Ichikado, Kazuya [Division of Respiratory Medicine, Saiseikai Kumamoto Hospital, 5-3-1 Tikami, Kumamoto, 861-4193 (Japan); Colby, Thomas V. [Department of Pathology, Mayo Clinic, Scottsdale, AZ (United States); Fukuoka, Junya [Laboratory of Pathology, Toyama University Hospital, Toyama (Japan); Taniguchi, Hiroyuki; Kondoh, Yasuhiro; Kataoka, Kensuke [Department of Respiratory Medicine, Tosei General Hospital, 160 Nishioiwake-cho, Seto City, Aichi (Japan); Yanagawa, Masahiro; Koyama, Mitsuhiro; Honda, Osamu; Tomiyama, Noriyuki [Department of Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0825 (Japan)

    2012-10-15

    Objectives: The aim of this study was to correlate high-resolution CT (HRCT) findings at the site of biopsy with the whole lung CT and pathologic diagnoses in usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP). Methods: The study included 35 patients (25 UIP and 10 NSIP) diagnosed both pathologically and clinically. 81 surgical biopsy specimens (54 UIP, and 27 NSIP) and extracted areas corresponding to biopsy sites on HRCT were analyzed. CT interpretations were compared with pathological diagnoses in both extracted images and the whole lung. Concordant and discordant cases in multiple extracted images were divided and analyzed. Then the whole cases were categorized by including or not at least one UIP diagnosis of extracted images and evaluated. Results: The diagnoses in extracted sites significantly correlated with pathological diagnoses (p = 0.047). There were significant differences in the concordances of extracted images compared with the diagnosis of whole lung and pathology (p = 0.008, 0.003, respectively). All 7 cases that were not concordant were diagnosed as radiological UIP with whole lung CT. The cases with at least one UIP diagnosis of extracted CT images were diagnosed as UIP in pathology more frequently (18 in 25) (p = 0.007). Conclusions: Radiological UIP in whole CT had more frequently discordant diagnoses from multiple extracted images than NSIP. And there were more cases in pathological UIP that included at least one UIP diagnosis of extracted images compared with pathological NSIP.

  11. Clinical features of usual interstitial pneumonia with anti-neutrophil cytoplasmic antibody in comparison with idiopathic pulmonary fibrosis.

    Science.gov (United States)

    Hosoda, Chiaki; Baba, Tomohisa; Hagiwara, Eri; Ito, Hiroyuki; Matsuo, Norikazu; Kitamura, Hideya; Iwasawa, Tae; Okudela, Koji; Takemura, Tamiko; Ogura, Takashi

    2016-07-01

    Myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) is occasionally positive in patients with usual interstitial pneumonia (UIP). However, the differences from idiopathic pulmonary fibrosis (IPF/UIP) have not been well documented. We aimed to clarify the clinical, radiological and pathological features of UIP associated with MPO-ANCA (ANCA/UIP). We retrospectively reviewed the medical records of 12 consecutive ANCA/UIP patients not manifesting microscopic polyangiitis and 108 IPF/UIP patients with no autoantibodies, both diagnosed by surgical lung biopsy. There was no significant difference in clinical background, laboratory results and pulmonary function tests between ANCA/UIP patients and IPF/UIP patients except for the percentage of bronchoalveolar lavage neutrophils. HRCT showed subpleural reticulation in both groups. Increased attenuation around honeycombing and cysts was significantly observed in ANCA/UIP. Pathologically, ANCA/UIP had more prominent inflammatory cell infiltration, lymphoid follicles with germinal centres and cellular bronchiolitis. During the disease course, three of 12 patients (25%) developed microscopic polyangiitis. Immunosuppressive treatment tended to be more effective in ANCA/UIP patients, and the survival time in ANCA/UIP patients tended to be longer than those with IPF/UIP. ANCA/UIP may be distinguishable from IPF/UIP with a combination of HRCT findings of increased attenuation around honeycombing and cysts and some of the characteristic pathological findings. In contrast to IPF/UIP, immunosuppressive treatment could be a therapeutic option for ANCA/UIP. © 2016 Asian Pacific Society of Respirology.

  12. Is catheter-directed foam sclerotherapy more effective than the usual foam sclerotherapy for treatment of the great saphenous vein?

    Science.gov (United States)

    Camillo, Orsini

    2018-01-01

    Objective This retrospective study presents the long-term results of catheter-directed foam sclerotherapy of the great saphenous vein. Method From January 2003 to June 2017, 277 patients with varices and great saphenous vein incompetence were treated with echo-guided foam sclerotherapy. Forty-six patients were treated with long-catheters guided by foam sclerotherapy. Foaming was carried out with sodium-tetra-decyl-sulphate. Results Results were examined in the two groups: A (long-catheters) and B (other procedures). The median overall follow-up was 52.1 months. In the A-group, the complete occlusion rate was 34/46 pts (73.9%) and partial occlusion was 10/46 (21.7%). In the B-group, respectively, 130/231 (56.2%) and 90/231 (38.9%). Comparisons between groups were statistically significant (p = 0.023; p = 0.021). Failures involved, respectively, 2/46 (4.3%) and 11/231 (4.7%) with no statistical significance. The complication rates were similar in the two groups. Conclusions In this long-term experience (median follow-up exceeding four years), foam-guided sclerotherapy of the great saphenous vein with a long-catheter turned out to be more effective than the usual foam-guided sclerotherapy.

  13. Conflicting results of robot-assisted versus usual gait training during postacute rehabilitation of stroke patients: a randomized clinical trial

    Science.gov (United States)

    Taveggia, Giovanni; Borboni, Alberto; Mulé, Chiara; Negrini, Stefano

    2016-01-01

    Robot gait training has the potential to increase the effectiveness of walking therapy. Clinical outcomes after robotic training are often not superior to conventional therapy. We evaluated the effectiveness of a robot training compared with a usual gait training physiotherapy during a standardized rehabilitation protocol in inpatient participants with poststroke hemiparesis. This was a randomized double-blind clinical trial in a postacute physical and rehabilitation medicine hospital. Twenty-eight patients, 39.3% women (72±6 years), with hemiparesis (Bobath approach were assigned randomly to an experimental or a control intervention of robot gait training to improve walking (five sessions a week for 5 weeks). Outcome measures included the 6-min walk test, the 10 m walk test, Functional Independence Measure, SF-36 physical functioning and the Tinetti scale. Outcomes were collected at baseline, immediately following the intervention period and 3 months following the end of the intervention. The experimental group showed a significant increase in functional independence and gait speed (10 m walk test) at the end of the treatment and follow-up, higher than the minimal detectable change. The control group showed a significant increase in the gait endurance (6-min walk test) at the follow-up, higher than the minimal detectable change. Both treatments were effective in the improvement of gait performances, although the statistical analysis of functional independence showed a significant improvement in the experimental group, indicating possible advantages during generic activities of daily living compared with overground treatment. PMID:26512928

  14. Changes in snowmelt runoff timing in western North America under a 'business as usual' climate change scenario

    Science.gov (United States)

    Stewart, I.T.; Cayan, D.R.; Dettinger, M.D.

    2004-01-01

    Spring snowmelt is the most important contribution of many rivers in western North America. If climate changes, this contribution may change. A shift in the timing of springtime snowmelt towards earlier in the year already is observed during 1948-2000 in many western rivers. Streamflow timing changes for the 1995-2099 period are projected using regression relations between observed streamflow-timing responses in each river, measured by the temporal centroid of streamflow (CT) each year, and local temperature (TI) and precipitation (PI) indices. Under 21st century warming trends predicted by the Parallel Climate Model (PCM) under business-as-usual greenhouse-gas emissions, streamflow timing trends across much of western North America suggest even earlier springtime snowmelt than observed to date. Projected CT changes are consistent with observed rates and directions of change during the past five decades, and are strongest in the Pacific Northwest, Sierra Nevada, and Rocky Mountains, where many rivers eventually run 30-40 days earlier. The modest PI changes projected by PCM yield minimal CT changes. The responses of CT to the simultaneous effects of projected TI and PI trends are dominated by the TI changes. Regression-based CT projections agree with those from physically-based simulations of rivers in the Pacific Northwest and Sierra Nevada.

  15. Ballistic strength training compared with usual care for improving mobility following traumatic brain injury: protocol for a randomised, controlled trial.

    Science.gov (United States)

    Williams, Gavin; Ada, Louise; Hassett, Leanne; Morris, Meg E; Clark, Ross; Bryant, Adam L; Olver, John

    2016-07-01

    Traumatic brain injury is the leading cause of disability in young adults aged 15 to 45 years. Mobility limitations are prevalent, and range in severity from interfering with basic day-to-day tasks to restricting participation in higher level social, leisure, employment and sporting activities. Despite the prevalence and severity of physical impairments, such as poor balance and spasticity, the main contributor to mobility limitations following traumatic brain injury is low muscle power generation. Strengthening exercises that are performed quickly are termed 'ballistic' as they are aimed at improving the rate of force production and, hence, muscle power. This is compared with conventional strength training, which is performed slowly and aims to improve maximum force production, yet has limited impact on mobility. In people recovering from traumatic brain injury: (1) is a 12-week ballistic strength-training program targeting the three muscle groups critical for walking more effective than usual care at improving mobility, strength and balance; and (2) does improved mobility translate to better health-related quality of life? A prospective, multi-centre, randomised, single-blind trial with concealed allocation will be conducted. Participants will be patients with a neurologically based movement disorder affecting mobility as a result of traumatic brain injury. Patients will be recruited during the acute phase of rehabilitation (n=166), from brain injury units in large metropolitan hospitals in Melbourne and Sydney, Australia. For 12 weeks, participants in the experimental group will have three 60-minute sessions of usual physiotherapy intervention replaced by three 60-minute sessions of strength training (ballistic strength, gait). The three key muscle groups responsible for forward propulsion will be targeted: ankle plantarflexors, hip flexors and the hip extensors. Initial loads will be low, to facilitate high contraction velocities. Progression to higher loads

  16. Brief Strategic Family Therapy Versus Treatment as Usual: Results of a Multisite Randomized Trial for Substance Using Adolescents

    Science.gov (United States)

    Robbins, Michael S.; Feaster, Daniel J.; Horigian, Viviana E.; Rohrbaugh, Michael; Shoham, Varda; Bachrach, Ken; Miller, Michael; Burlew, Kathleen A.; Hodgkins, Candy; Carrion, Ibis; Vandermark, Nancy; Schindler, Eric; Werstlein, Robert; Szapocznik, José

    2012-01-01

    Objective To determine the effectiveness of brief strategic family therapy (BSFT; an evidence-based family therapy) compared to treatment as usual (TAU) as provided in community-based adolescent outpatient drug abuse programs. Method A randomized effectiveness trial in the National Drug Abuse Treatment Clinical Trials Network compared BSFT to TAU with a multiethnic sample of adolescents (213 Hispanic, 148 White, and 110 Black) referred for drug abuse treatment at 8 community treatment agencies nationwide. Randomization encompassed both adolescents’ families (n = 480) and the agency therapists (n = 49) who provided either TAU or BSFT services. The primary outcome was adolescent drug use, assessed monthly via adolescent self-report and urinalysis for up to 1 year post randomization. Secondary outcomes included treatment engagement (≥2 sessions), retention (≥8 sessions), and participants’ reports of family functioning 4, 8, and 12 months following randomization. Results No overall differences between conditions were observed in the trajectories of self-reports of adolescent drug use. However, the median number of days of self-reported drug use was significantly higher, χ2(1) = 5.40, p family members in treatment and in improving parent reports of family functioning, χ2(2) = 9.10, p < .011. Conclusions We discuss challenges in treatment implementation in community settings and provide recommendations for further research. PMID:21967492

  17. Transfusão sangüínea no intra-operatório, complicações e prognóstico Transfusión sanguínea en el intraoperatorio, complicaciones y pronóstico Complications and prognosis of intraoperative blood transfusion

    Directory of Open Access Journals (Sweden)

    João Manoel Silva Junior

    2008-10-01

    mortalidade. Os escores APACHE II, POSSUM e maior número de transfusões foram fatores de riscos independentes de pior prognóstico no pós-operatório.JUSTIFICATIVA Y OBJETIVOS: Transfusiones sanguíneas en el intraoperatorio están asociadas al aumento de complicaciones en el postoperatorio y costes hospitalarios. Por tanto, este estudio evaluó las características, complicaciones y los posibles factores de riesgos para muerte en pacientes quirúrgicos que necesitaron transfusiones sanguíneas en el intraoperatorio. MÉTODO: Categoría prospectiva, durante el período de un año, en el centro quirúrgico de hospital terciario. Se incluyeron pacientes con edad por encima de los 18 años que necesitaron transfusiones sanguíneas en el intraoperatorio. Testigos de Jeová, pacientes que recibieron transfusiones previas, fracaso coronario y lesión encefálica aguda quedaron excluidos del estudio. RESULTADOS: El estudio involucró a 80 pacientes, con una edad promedio entre los 68,4 ± 14,1 años. Los pacientes ASA II eran prevalecientes con 69,6% de los casos, las puntuaciones APACHE II y POSSUM fueron, como promedio respectivamente de 13,6 ± 4,4 y 37,5 ± 11,4. La hemoglobina promedio al momento de la transfusión era de 8,2 ± 1,8 g.dL-1 y un 19% de los pacientes tuvieron hemoglobina por encima de 10 g.dL-1. Los pacientes recibieron como promedio 2,2 ± 0,9 UI de concentrados de hematíes. La mortalidad hospitalaria fue de un 26,3%. Las complicaciones postransfusiones totalizaron un 57,5% de los casos en el postoperatorio y la más frecuente fue la infección. Fueron factores independientes de muerte en la regresión logística las puntuaciones APACHE II (OR = 1,34; IC 95% 1,102-1,622, POSSUM (OR = 1,08; IC 95% 1,008 - 1,150 y número de unidades de concentrados de hematíes recibidos (OR = 2,22; IC 95% 1,100 - 4,463. Mientras mayor es el número de transfusiones sanguíneas, mayores son las incidencias de las complicaciones y de la mortalidad. CONCLUSIONES: El valor de la

  18. Alpha radioactivity monitoring related to Radon-222 in water from wells in metropolitan area of Curitiba (PR), Brazil; Monitoramento da radioatividade alfa relacionada ao radonio-222 em aguas de pocos da regiao metropolitana de Curitiba (PR)

    Energy Technology Data Exchange (ETDEWEB)

    Correa, Janine Nicolosi; Paschuk, Sergei Anatolyevich; Kappke, Jaqueline; Claro, Flavia Del; Perna, Allan Felipe Nunes; Reque, Marilson, E-mail: janine_nicolosi@hotmail.com [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil); Denyak, Valeriy; Schelin, Hugo Reuters [Instituto de Pesquisa Pele Pequeno Principe (IPPPP), Curitiba, PR (Brazil); Rocha, Zildete; Santos, Talita Oliveira [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2015-04-15

    This research objective was to assess the level of randon-222 concentration in well water of the metropolitan region of Curitiba, Parana. Current work presents the results of indoor {sup 222}Rn activity ground water samples from artesian wells from aquifers of the region. The studies of radon activity in water were performed using the radon detector AlphaGUARD. The calculations of initial radon activity in water were done considering the {sup 222}Rn decay correction as well as equilibrium level of {sup 222}Rn and {sup 226}Ra observed after 30 days of measurements. Obtained results show that about 70% of measured activity levels of {sup 222}Rn are higher than the recommended value of 11.1 Bq.L{sup -1}, which represent the risk for the human health associated with this radionuclide. The case study showed that previous measurements of radon are recommended for a construction project is implemented. In this case, it is observed that the radon concentrations decrease about 56% in the first water tank and 83% in the second water tank over the well. This fact shows that the actions for mitigation of radon are viable and do not require major modifications to the usual systems of construction. (author)

  19. Rheological behaviour of Portland G and polyurethane slurries applied to oil wells submitted a steam injection; Comportamento reologico de pastas de cimento Portland G e poliuretana para cimentacao de pocos sujeitos a injecao de vapor

    Energy Technology Data Exchange (ETDEWEB)

    Bezerra, U.; Martinelli, A.E.; Melo, D.M.; Silva, L.; Lima, F. [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil); Araujo, R.G. [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2004-07-01

    Two point of view can be focused with respect to the behavior of slurries for cementing. The first refers to the rheological properties, they should submit to the established limits by the standards. A second point of view refers to the problems originated from the use of the secondary recovery by steam injection, that wakes up tensile tension in the sheath. A solution for this problem is the addition of thermal stronger polymer to the cement slurry, increasing your tensile strength. However, this practice is usually accompanied by the increase of the viscosity of the slurry, that make difficult the pumping. Studies involving rheological aspects and thickening time were accomplished with slurries additivated with polyurethane for evaluation of your pumpability. Correlations were observed among polyurethane concentration, viscosity and thickening time. Mathematical models are proposed correlating the three parameters. A good values were found for concentrations among 1,5 % and 2,5 % of polyurethane. The polyurethane actuated as a charge reducing the slurry fluidity, then the increase of the viscosity. In the condition of setting of cement, the polyurethane stimulated a better dispersion and approach of the particles of the cement with water, accelerating the typical precipitation process of the cement hydration. (author)

  20. Economic evaluation of an intensive group training protocol compared with usual care physiotherapy in patients with chronic low back pain.

    Science.gov (United States)

    van der Roer, Nicole; van Tulder, Maurits; van Mechelen, Willem; de Vet, Henrica

    2008-02-15

    Economic evaluation from a societal perspective conducted alongside a randomized controlled trial with a follow-up of 52 weeks. To evaluate the cost effectiveness and cost utility of an intensive group training protocol compared with usual care physiotherapy in patients with nonspecific chronic low back pain. The intensive group training protocol combines exercise therapy, back school, and behavioral principles. Two studies found a significant reduction in absenteeism for a graded activity program in occupational health care. This program has not yet been evaluated in a primary care physiotherapy setting. Participating physical therapists in primary care recruited 114 patients with chronic nonspecific low back pain. Eligible patients were randomized to either the protocol group or the guideline group. Outcome measures included functional status (Roland Morris Disability Questionnaire), pain intensity (11-point numerical rating scale), general perceived effect and quality of life (EuroQol-5D). Cost data were measured with cost diaries and included direct and indirect costs related to low back pain. After 52 weeks, the direct health care costs were significantly higher for patients in the protocol group, largely due to the costs of the intervention. The mean difference in total costs amounted to [Euro sign] 233 (95% confidence interval: [Euro sign] -2.185; [Euro sign] 2.764). The cost-effectiveness planes indicated no significant differences in cost effectiveness between the 2 groups. The results of this economic evaluation showed no difference in total costs between the protocol group and the guideline group. The differences in effects were small and not statistically significant. At present, national implementation of the protocol is not recommended.

  1. Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia

    International Nuclear Information System (INIS)

    Parra, E.R.; Pincelli, M.S.; Teodoro, W.R.; Velosa, A.P.P.; Martins, V.; Rangel, M.P.; Barbas-Filho, J.V.; Capelozzi, V.L.

    2014-01-01

    Limitations on tissue proliferation capacity determined by telomerase/apoptosis balance have been implicated in pathogenesis of idiopathic pulmonary fibrosis. In addition, collagen V shows promise as an inductor of apoptosis. We evaluated the quantitative relationship between the telomerase/apoptosis index, collagen V synthesis, and epithelial/fibroblast replication in mice exposed to butylated hydroxytoluene (BHT) at high oxygen concentration. Two groups of mice were analyzed: 20 mice received BHT, and 10 control mice received corn oil. Telomerase expression, apoptosis, collagen I, III, and V fibers, and hydroxyproline were evaluated by immunohistochemistry, in situ detection of apoptosis, electron microscopy, immunofluorescence, and histomorphometry. Electron microscopy confirmed the presence of increased alveolar epithelial cells type 1 (AEC1) in apoptosis. Immunostaining showed increased nuclear expression of telomerase in AEC type 2 (AEC2) between normal and chronic scarring areas of usual interstitial pneumonia (UIP). Control lungs and normal areas from UIP lungs showed weak green birefringence of type I and III collagens in the alveolar wall and type V collagen in the basement membrane of alveolar capillaries. The increase in collagen V was greater than collagens I and III in scarring areas of UIP. A significant direct association was found between collagen V and AEC2 apoptosis. We concluded that telomerase, collagen V fiber density, and apoptosis evaluation in experimental UIP offers the potential to control reepithelization of alveolar septa and fibroblast proliferation. Strategies aimed at preventing high rates of collagen V synthesis, or local responses to high rates of cell apoptosis, may have a significant impact in pulmonary fibrosis

  2. Cave exploitation by an usual epigean species: a review on the current knowledge on fire salamander breeding in cave

    Directory of Open Access Journals (Sweden)

    Raoul Manenti

    2017-11-01

    Full Text Available The fire salamander (Salamandra salamandra is a relatively common epigean amphibian, widely distributed throughout Europe, which usually gives birth to aquatic larvae. Even if epigean streams represent the most common places in which the species breeds, in some countries caves with underground waters are also used. To improve our understanding of the habitat features allowing successful breeding of salamanders in underground sites, we combined an exhaustive review of the available literature, especially the grey one, with direct observations performed from 2008 to 2017 in several natural and artificial caves of Lombardy, Liguria and Tuscany (Italy, Ariège and Provence (France. We provide a synthesis of published and unpublished caves in which the fire salamander breeding has been observed, along with a synthesis of the investigated ecological, behavioural and morphological traits. The use of underground sites is reported in several published papers and appears to be a common phenomenon not limited to single karst areas. The absence of predators, the relative stability of the aquatic habitats and the possibility to exploit new ecological resources are environmental factors that favour the breeding of the fire salamander. Our synthesis suggests that breeding of fire salamanders in caves is not a random event, but a widespread phenomenon that may be linked to specific biogeographical factors. Further insights may be obtained by performing genetic analyses on both cave and epigean populations, and considering larger landscape scales for ecological studies as well. Gene flow between salamanders that breed in caves and in streams probably occurs, but on the other hand, assortative mating might limit it, thus allowing the conservation of local adaptations driving successful cave colonisation.

  3. Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia

    Energy Technology Data Exchange (ETDEWEB)

    Parra, E.R.; Pincelli, M.S. [Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Teodoro, W.R.; Velosa, A.P.P. [Disciplina de Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Martins, V.; Rangel, M.P.; Barbas-Filho, J.V.; Capelozzi, V.L. [Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil)

    2014-06-04

    Limitations on tissue proliferation capacity determined by telomerase/apoptosis balance have been implicated in pathogenesis of idiopathic pulmonary fibrosis. In addition, collagen V shows promise as an inductor of apoptosis. We evaluated the quantitative relationship between the telomerase/apoptosis index, collagen V synthesis, and epithelial/fibroblast replication in mice exposed to butylated hydroxytoluene (BHT) at high oxygen concentration. Two groups of mice were analyzed: 20 mice received BHT, and 10 control mice received corn oil. Telomerase expression, apoptosis, collagen I, III, and V fibers, and hydroxyproline were evaluated by immunohistochemistry, in situ detection of apoptosis, electron microscopy, immunofluorescence, and histomorphometry. Electron microscopy confirmed the presence of increased alveolar epithelial cells type 1 (AEC1) in apoptosis. Immunostaining showed increased nuclear expression of telomerase in AEC type 2 (AEC2) between normal and chronic scarring areas of usual interstitial pneumonia (UIP). Control lungs and normal areas from UIP lungs showed weak green birefringence of type I and III collagens in the alveolar wall and type V collagen in the basement membrane of alveolar capillaries. The increase in collagen V was greater than collagens I and III in scarring areas of UIP. A significant direct association was found between collagen V and AEC2 apoptosis. We concluded that telomerase, collagen V fiber density, and apoptosis evaluation in experimental UIP offers the potential to control reepithelization of alveolar septa and fibroblast proliferation. Strategies aimed at preventing high rates of collagen V synthesis, or local responses to high rates of cell apoptosis, may have a significant impact in pulmonary fibrosis.

  4. Mechanisms underlying mindfulness-based addiction treatment versus cognitive behavioral therapy and usual care for smoking cessation.

    Science.gov (United States)

    Spears, Claire Adams; Hedeker, Donald; Li, Liang; Wu, Cai; Anderson, Natalie K; Houchins, Sean C; Vinci, Christine; Hoover, Diana Stewart; Vidrine, Jennifer Irvin; Cinciripini, Paul M; Waters, Andrew J; Wetter, David W

    2017-11-01

    To examine cognitive and affective mechanisms underlying mindfulness-based addiction treatment (MBAT) versus cognitive-behavioral therapy (CBT) and usual care (UC) for smoking cessation. Participants in the parent study from which data were drawn (N = 412; 54.9% female; 48.2% African American, 41.5% non-Latino White, 5.4% Latino, 4.9% other; 57.6% annual income <$30,000) were randomized to MBAT (n = 154), CBT (n = 155), or UC (n = 103). From quit date through 26 weeks postquit, participants completed measures of emotions, craving, dependence, withdrawal, self-efficacy, and attentional bias. Biochemically confirmed 7-day smoking abstinence was assessed at 4 and 26 weeks postquit. Although the parent study did not find a significant treatment effect on abstinence, mixed-effects regression models were conducted to examine treatment effects on hypothesized mechanisms, and indirect effects of treatments on abstinence were tested. Participants receiving MBAT perceived greater volitional control over smoking and evidenced lower volatility of anger than participants in both other treatments. However, there were no other significant differences between MBAT and CBT. Compared with those receiving UC, MBAT participants reported lower anxiety, concentration difficulties, craving, and dependence, as well as higher self-efficacy for managing negative affect without smoking. Indirect effects of MBAT versus UC on abstinence occurred through each of these mechanisms. Whereas several differences emerged between MBAT and UC, MBAT and CBT had similar effects on several of the psychosocial mechanisms implicated in tobacco dependence. Results help to shed light on similarities and differences between mindfulness-based and other active smoking cessation treatments. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  5. Impulsivity and decision-making in obsessive-compulsive disorder after effective deep brain stimulation or treatment as usual.

    Science.gov (United States)

    Grassi, Giacomo; Figee, Martijn; Ooms, Pieter; Righi, Lorenzo; Nakamae, Takashi; Pallanti, Stefano; Schuurman, Rick; Denys, Damiaan

    2018-06-04

    Impulsivity and impaired decision-making have been proposed as obsessive-compulsive disorder (OCD) endophenotypes, running in OCD and their healthy relatives independently of symptom severity and medication status. Deep brain stimulation (DBS) targeting the ventral limb of the internal capsule (vALIC) and the nucleus accumbens (Nacc) is an effective treatment strategy for treatment-refractory OCD. The effectiveness of vALIC-DBS for OCD has been linked to its effects on a frontostriatal network that is also implicated in reward, impulse control, and decision-making. While vALIC-DBS has been shown to restore reward dysfunction in OCD patients, little is known about the effects of vALIC-DBS on impulsivity and decision-making. The aim of the study was to compare cognitive impulsivity and decision-making between OCD patients undergoing effective vALIC-DBS or treatment as usual (TAU), and healthy controls. We used decision-making performances under ambiguity on the Iowa Gambling Task and reflection impulsivity on the Beads Task to compare 20 OCD patients effectively treated with vALIC-DBS, 40 matched OCD patients undergoing effective TAU (medication and/or cognitive behavioural therapy), and 40 healthy subjects. Effective treatment was defined as at least 35% improvement of OCD symptoms. OCD patients, irrespective of treatment modality (DBS or TAU), showed increased reflection impulsivity and impaired decision-making compared to healthy controls. No differences were observed between OCD patients treated with DBS or TAU. OCD patients effectively treated with vALIC-DBS or TAU display increased reflection impulsivity and impaired decision-making independent of the type of treatment.

  6. Association of heart rate and blood pressure among European adolescents with usual food consumption: The HELENA study.

    Science.gov (United States)

    Julián-Almárcegui, C; Vandevijvere, S; Gottrand, F; Beghin, L; Dallongeville, J; Sjöstrom, M; Leclercq, C; Manios, Y; Widhalm, K; Ferreira De Morares, A C; Gónzalez-Gross, M; Stehle, P; Castillo, M J; Moreno, L A; Kersting, M; Vyncke, K; De Henauw, S; Huybrechts, I

    2016-06-01

    In adults, there is some evidence that improving diet reduces blood pressure (BP) and the subsequent risk of cardiovascular diseases (CVDs). However, studies that analyse this association in adolescents are still scarce. The objective of the present study was to examine the associations between heart rate, systolic (SBP), diastolic (DBP) and mean arterial blood pressure (MAP) among European adolescents and usual intake of vegetables, fruits, dairy products, meat, fish, high-sugar foods and savoury snacks. In total, 2283 adolescents from the HELENA-study (12.5-17.5 years old; 1253 girls) were included. Dietary intake was assessed using two computerized 24-hour dietary recalls. Age, sex, body mass index, maternal educational level, physical activity and Tanner stage were considered as confounders. Associations were examined by mixed model analysis stratified by sex. Tests for trend were assessed by tertiles of intake while controlling for the aforementioned confounders. Dairy products and fish intake were negatively associated with BP and heart rate. Significant decreasing trends were observed for heart rate and BP across tertiles of dairy products, fish intake and high-sugar foods intake (p blood pressure and heart rate have been found in European adolescents. Dietary intervention studies are needed to explore these associations in the context of the modification of several risk factors for the prevention of cardiovascular diseases. Copyright © 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

  7. Complicaciones tardías en siete gastrectomizados

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    Jaime Campos

    1972-01-01

    Full Text Available Seven patients with complications due to gastrectomy performed several years back are described. Their main symptons were: weight loss in 6, diarrhea in 5, anemia in 5, blind loop syndrome in 5 and dumping syndrome in 5. Some of the patients developed mild absorption disturbances such us steatorrhea in 3, abnormal d-xylosa excretion in 1 and significant atrophy of the intestinal mucosa in 2. In three patients we found pulmonar T.B.C

  8. Avaliação de parâmetros histológicos na pneumonia intersticial usual (fibrose pulmonar idiopática Evaluation of the histological parameters in usual interstitial pneumonia (idiopathic pulmonary fibrosis

    Directory of Open Access Journals (Sweden)

    RIMARCS GOMES FERREIRA

    2000-12-01

    Full Text Available A fibrose pulmonar idiopática (alveolite fibrosante criptogênica é uma doença pulmonar intersticial progressiva de etiologia desconhecida, morfologicamente reconhecida como pneumonia intersticial usual. Desde a publicação de Hamman e Rich (1944 até os dias atuais, uma das grandes preocupações foi a tentativa de encontrar um marcador histológico para correlacionar com prognóstico e resposta terapêutica. A busca desta situação não tem sido muito alentadora, pois existem vários pontos duvidosos na patogênese desta doença. Admite-se que a resposta terapêutica desta entidade se relaciona com a celularidade e fibrose presentes no tecido. A proposta deste estudo é descrever os resultados de método semiquantitativo segundo a avaliação independente de dois patologistas, das alterações exsudativo-inflamatórias, reparativo-fibróticas e de vias aéreas, em 24 pacientes com diagnóstico de fibrose pulmonar idiopática, submetidos à biópsia a céu aberto. Foram analisados 14 parâmetros histológicos segundo escala de 0 a 5 para as alterações intersticiais e de 0 a 2 para o comprometimento de vias aéreas e de espaços aéreos. Da análise independente realizada pelos dois observadores constatou-se concordância significante em todas as variáveis histológicas com Kw (teste de Kappa indo de 0,47 a 0,92. Apenas na análise da intensidade da inflamação septal as discordâncias também foram significantes, sugerindo que para este parâmetro a percentagem de comprometimento tecidual deve ser previamente discutida entre os observadores. O método utilizado demonstrou ser rápido e eficiente.Idiopathic pulmonary fibrosis (cryptogenic fibrosing alveolitis is a progressive interstitial pulmonary disease of unknown etiology. Since Hamman's and Rich's (1944 reports, many studies have tried to find a histological marker for the correlation between prognosis and response to therapy. However, there are many doubts regarding pathogenesis

  9. Augmenting Outpatient Alcohol Treatment as Usual With Online Alcohol Avoidance Training: Protocol for a Double-Blind Randomized Controlled Trial.

    Science.gov (United States)

    Bratti-van der Werf, Marleen Kj; Laurens, Melissa C; Postel, Marloes G; Pieterse, Marcel E; Ben Allouch, Somaya; Wiers, Reinout W; Bohlmeijer, Ernst T; Salemink, Elske

    2018-03-01

    Recent theoretical models emphasize the role of impulsive processes in alcohol addiction, which can be retrained with computerized Cognitive Bias Modification (CBM) training. In this study, the focus is on action tendencies that are activated relatively automatically. The aim of the study is to examine the effectiveness of online CBM Alcohol Avoidance Training using an adapted Approach-Avoidance Task as a supplement to treatment as usual (TAU) in an outpatient treatment setting. The effectiveness of 8 online sessions of CBM Alcohol Avoidance Training added to TAU is tested in a double-blind, randomized controlled trial with pre- and postassessments, plus follow-up assessments after 3 and 6 months. Participants are adult patients (age 18 years or over) currently following Web-based or face-to-face TAU to reduce or stop drinking. These patients are randomly assigned to a CBM Alcohol Avoidance or a placebo training. The primary outcome measure is a reduction in alcohol consumption. We hypothesize that TAU + CBM will result in up to a 13-percentage point incremental effect in the number of patients reaching the safe drinking guidelines compared to TAU + placebo CBM. Secondary outcome measures include an improvement in health status and a decrease in depression, anxiety, stress, and possible mediation by the change in approach bias. Finally, patients' adherence, acceptability, and credibility will be examined. The trial was funded in 2014 and is currently in the active participant recruitment phase (since May 2015). Enrolment will be completed in 2019. First results are expected to be submitted for publication in 2020. The main purpose of this study is to increase our knowledge about the added value of online Alcohol Avoidance Training as a supplement to TAU in an outpatient treatment setting. If the added effectiveness of the training is proven, the next step could be to incorporate the intervention into current treatment. Netherlands Trial Register NTR5087; http

  10. Podiatry intervention versus usual care to prevent falls in care homes: pilot randomised controlled trial (the PIRFECT study).

    Science.gov (United States)

    Wylie, Gavin; Menz, Hylton B; McFarlane, Sarah; Ogston, Simon; Sullivan, Frank; Williams, Brian; Young, Zoe; Morris, Jacqui

    2017-07-12

    Common foot problems are independent risk factors for falls in older people. There is evidence that podiatry can prevent falls in community-dwelling populations. The feasibility of implementing a podiatry intervention and trial in the care home population is unknown. To inform a potential future definitive trial, we performed a pilot randomised controlled trial to assess: (i) the feasibility of a trial of a podiatry intervention to reduce care home falls, and (ii) the potential direction and magnitude of the effect of the intervention in terms of number of falls in care home residents. Informed by Medical Research Council guidance on developing and evaluating complex interventions, we conducted a single blind, pilot randomised controlled trial in six care homes in the East of Scotland. Participants were randomised to either: (i) a three month podiatry intervention comprising core podiatry care, foot and ankle exercises, orthoses and footwear provision or (ii) usual care. Falls-related outcomes (number of falls, time to first fall) and feasibility-related outcomes (recruitment, retention, adherence, data collection rates) were collected. Secondary outcomes included: generic health status, balance, mobility, falls efficacy, and ankle joint strength. 474 care home residents were screened. 43 (9.1%) participants were recruited: 23 to the intervention, 20 to control. Nine (21%) participants were lost to follow-up due to declining health or death. It was feasible to deliver the trial elements in the care home setting. 35% of participants completed the exercise programme. 48% reported using the orthoses 'all or most of the time'. Completion rates of the outcome measures were between 93% and 100%. No adverse events were reported. At the nine month follow-up period, the intervention group per-person fall rate was 0.77 falls vs. 0.83 falls in the control group. A podiatry intervention to reduce falls can be delivered to care home residents within a pilot randomised

  11. Usual interstitial pneumonia and non-specific interstitial pneumonia: serial thin-section CT findings correlated with pulmonary function

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    Jeong, Yeon Joo; Lee, Kyung Soo; Chung, Man Pyo; Chung Myung Jin; Han, Joung Ho [Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Mueller, Nestor L. [University of British Columbia, Vancouver (Canada); Colby, Thomas V. [Mayo Clinic Scottsdale, Scottsdale (United States); Kim, Seon Woo [Samsung Medical Center, Seoul (Korea, Republic of)

    2005-09-15

    We wanted to demonstrate and compare the serial high-resolution CTs (HRCT) and the pulmonary function test (PFT) findings of the usual interstitial pneumonia (UIP) and the non-specific interstitial pneumonia (NSIP). The serial HRCT scans and the PFT results were retrospectively analysed and compared for 35 patients having UIP without significant honeycombing (UIP-w/o hc, < 5% of honeycombing at CT), 35 patients having UIP with honeycombing (UIP-w/i hc, {>=} 5% of honeycombing), and 25 patients with NSIP. The mortality rates were also compared. Follow-up CT scans were available in 75 patients (29 UIP-w/o hc patients, 22 UIP-w/i hc patients and 24 NSIP patients) and the follow-up periods ranged from 150 to 2,370 days. The initial and follow-up PFT data were available for 71 patients. On the initial CT, significant differences were present between the UIP-w/i hc patients and both the UIP-w/o hc patients and the NSIP patients in the overall extent, ground-glass opacity (GGO) away from the reticulation, reticulation and honeycombing (all {rho} < 0.05). Improvement was noticed in five (17%) of 29 UIP-w/o hc patients, none of 22 UIP-w/i hc patients, and 9 (37%) of 24 NSIP patients; deterioration was noted in six (21%) UIP-w/o hc patients, two (9%) UIP-w/i hc patients and three (13%) NSIP patients ({rho} 0.044 between UIP-w/o and UIP-w/i hc; {rho} = 0.637 between UIP-w/o hc and NSIP; {rho} = 0.007 between UIP-w/i hc and NSIP). The serial changes of the pulmonary function in the NSIP patients were different from those noted for the UIP-w/i hc and UIP-w/o hc patients ({rho} = 0.440 between UIP-w/o and UIP-w/i hc; {rho} = 0.022 between UIP-w/o hc and NSIP; {rho} =0.003 between UIP-w/i hc and NSIP). Five (14%) of the 35 patients with UIP-w/o hc, 16 (46%) of the 35 patients with UIP-w/i hc and three (12%) of the 25 patients with NSIP died ({rho} = 0.002, comparison for the three groups). On CT, NSIP and UIP-w/o hc patients have similar patterns of parenchymal abnormalities and

  12. Usual care and management of fall risk increasing drugs in older dizzy patients in Dutch general practice

    Science.gov (United States)

    Stam, Hanneke; Harting, Thomas; van der Sluijs, Marjolijn; van Marum, Rob; van der Horst, Henriëtte; van der Wouden, Johannes C.; Maarsingh, Otto R.

    2016-01-01

    Objective For general practitioners (GPs) dizziness is a challenging condition to deal with. Data on the management of dizziness in older patients are mostly lacking. Furthermore, it is unknown whether GPs attempt to decrease Fall Risk Increasing Drugs (FRIDs) use in the management of dizziness in older patients. The aim of this study is to gain more insight into GP’s management of dizziness in older patients, including FRID evaluation and adjustment. Design Data were derived from electronic medical records, obtained over a 12-month period in 2013. Setting Forty-six Dutch general practices. Patients The study sample comprised of 2812 older dizzy patients of 65 years and over. Patients were identified using International Classification of Primary Care codes and free text. Main outcome measures Usual care was categorized into wait-and-see strategy (no treatment initiated); education and advice; additional testing; medication adjustment; and referral. Results Frequently applied treatments included a wait-and-see strategy (28.4%) and education and advice (28.0%). Additional testing was performed in 26.8%; 19.0% of the patients were referred. Of the patients 87.2% had at least one FRID prescription. During the observation period, GPs adjusted the use of one or more FRIDs for 11.7% of the patients. Conclusion This study revealed a wide variety in management strategies for dizziness in older adults. The referral rate for dizziness was high compared to prior research. Although many older dizzy patients use at least one FRID, FRID evaluation and adjustment is scarce. We expect that more FRID adjustments may reduce dizziness and dizziness-related impairment. Key PointsIt is important to know how general practitioners manage dizziness in older patients in order to assess potential cues for improvement.This study revealed a wide variety in management strategies for dizziness in older patients.There was a scarcity in Fall Risk Increasing Drug (FRID) evaluation and adjustment

  13. The added value of food frequency questionnaire (FFQ) information to estimate the usual food intake based on repeated 24-hour recalls.

    Science.gov (United States)

    Ost, Cloë; De Ridder, Karin A A; Tafforeau, Jean; Van Oyen, Herman

    2017-01-01

    Statistical methods to model the usual dietary intake of foods in a population generally ignore the additional information on the never-consumers. The objective of this study is to determine the added value of Food Frequency Questionnaire (FFQ) data allowing distinguishing the never-consumers from the non-consumers while modeling the usual intake distribution. Three food items with a different proportion of never-consumers were selected from the database of the Belgian food consumption survey of 2004 ( N  = 3200). The usual intake distribution for these food items was modeled with the Statistical Program for Analysis of Dietary Exposure (SPADE) and modeling parameters were extracted. These parameters were used to simulate (a) a new database with two 24-h recalls per respondent and (b) a "true" usual intake distribution. The usual intake distribution from the new database was obtained by modeling the 24-h recalls with SPADE, once without and once with the inclusion of the FFQ data on the never-consumers. Ratios were calculated for the different percentiles of the usual intake distribution: the modeled usual intake (g/day) (for both SPADE with and without the inclusion of FFQ data on never-consumers) was divided by the corresponding percentile of the simulated "true" usual intake (g/day). The closer the ratio is to one, the better the model fits the data. Inclusion of the FFQ information to identify the never-consumers did not improve the estimation of the higher percentiles of the usual intake distribution. However, taking into account this FFQ information improved the estimation of the lower percentiles of the usual intake distribution even when the proportion of never-consumers was low. The inclusion of FFQ information to identify the never-consumers is beneficial when interested in the whole usual intake distribution or in the lower percentiles only, no matter how low the proportion of never-consumers for that food item may be. However, when interest is only in

  14. Incidência de complicações relacionadas à massagem do seio carotídeo em 502 pacientes ambulatoriais Incidencia de complicaciones relacionadas al masaje del seno carotídeo en 502 pacientes ambulatorios Complications related to carotid sinus massage in 502 ambulatory patients

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    Gustavo de Castro Lacerda

    2009-02-01

    aterosclerótica y cardiopatía. MÉTODOS: Estudio transversal. Criterios de inclusión: pacientes ambulatorios con edad >50 años, orientados a realizar el electrocardiograma (ECG. Criterios de exclusión: individuos que no aceptaron participar de un estudio sobre la prevalencia de la respuesta cardioinhibitoria al MSC; pacientes con demencia; portadores de marcapaso; individuos con soplo carotídeo o historia de ACV o IAM en los últimos 3 meses. Se realizó el MSC en posición supina durante 10 segundos. Se consideraron complicaciones del MSC: la ocurrencia de arritmias sostenidas y el aparecimiento de déficit neurológico, ya sea durante el MSC, ya sea en las 24 horas subsecuentes a su término. RESULTADOS: Se seleccionaron, de modo aleatorio, a 562 pacientes, de un total de 1.686 individuos con los criterios de inclusión. El total de 60 individuos presentaron criterios de exclusión. Los 502 pacientes restantes (el 52% varones, edad promedio de 65 años, el 69% cardiópatas y el 50% con enfermedad aterosclerótica se sometieron a 1.053 MSC. La cantidad de dos pacientes presentaron complicaciones (0,4%; IC95%:0%-0,9%. Un varón de 71 años presentó monoparesia del brazo izquierdo con regresión completa en 30 minutos. Otro varón, de 56 años, presentó hemianopsia homónima izquierda, que retrocedió en 7 días. CONCLUSIÓN: La incidencia de complicaciones relacionadas al MSC resultó pequeña, particularmente cuando se consideró que la población sometida a la maniobra era anciana y con alta prevalencia tanto de cardiopatía estructural como de enfermedad aterosclerótica.BACKGROUND: The carotid sinus massage (CSM is a simple and low-cost technique with many indications. OBJECTIVE: To determine the safety of CSM in outpatients with high prevalence of atherosclerotic disease and cardiopathy. METHODS: A transversal study. Inclusion criteria: Outpatients aged >50 years, referred for ECG. Exclusion criteria: Individuals that refused to participate in a study on the

  15. A randomized controlled trial on early physiotherapy intervention versus usual care in acute care unit for elderly: potential benefits in light of dietary intakes.

    NARCIS (Netherlands)

    Blanc-Bisson, C.; Dechamps, A.A.; Gouspillou, G.; Dehail, P.; Bourdel-Marchasson, I.

    2008-01-01

    OBJECTIVE: To evaluate effects of early intensive physiotherapy during acute illness on post hospitalization activity daily living autonomy (ADL). DESIGN: Prospective randomized controlled trial of intensive physiotherapy rehabilitation on day 1 to 2 after admission until clinical stability or usual

  16. Nurse home visits with or without alert buttons versus usual care in the frail elderly: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Favela J

    2013-01-01

    Full Text Available Jesús Favela,1 Luis A Castro,2 Francisco Franco-Marina,3 Sergio Sánchez-García,4 Teresa Juárez-Cedillo,4 Claudia Espinel Bermudez,4 Julia Mora-Altamirano,4 Marcela D Rodriguez,5 Carmen García-Peña41Center for Scientific Research and Higher Education of Ensenada, Ensenada, Baja California, Mexico; 2Sonora Institute of Technology, Ciudad Obregon, Mexico; 3National Institute of Respiratory Diseases, Mexican Ministry of Health, Mexico City, Mexico; 4Epidemiologic and Health Service Research Unit, Aging Area, XXI Century National Medical Center, Mexican Institute of Social Security, Mexico City, Mexico; 5School of Engineering, MyDCI, Autonomous University of Baja California, Mexicali, MexicoObjective: To assess whether an intervention based on nurse home visits including alert buttons (NV+AB is effective in reducing frailty compared to nurse home visits alone (NV-only and usual care (control group for older adults.Design: Unblinded, randomized, controlled trial.Setting: Insured population covered by the Mexican Social Security Institute living in the city of Ensenada, Baja California, Mexico.Participants: Patients were aged over 60 years with a frailty index score higher than 0.14.Intervention: After screening and informed consent, participants were allocated randomly to the control, NV+AB, or NV-only groups.Measurements: The primary outcome was the frailty score 9 months later. Quality of life, depression, comorbidities, health status, and health service utilization were also considered.Results: The framing sample included 819 patients. Of those, 591 were not located because they did not have a landline/telephone (341 patients, they had died (107, they were ill (50, or they were not currently living in the city (28. A screening interview was applied to 228 participants, and 57 had a score ≤0.14, 171 had ≥0.14, and 16 refused to complete the baseline questionnaire. A home visit was scheduled for 155 patients. However, 22 did not complete

  17. Evaluating wait times from screening to breast cancer diagnosis among women undergoing organised assessment vs usual care.

    Science.gov (United States)

    Chiarelli, Anna M; Muradali, Derek; Blackmore, Kristina M; Smith, Courtney R; Mirea, Lucia; Majpruz, Vicky; O'Malley, Frances P; Quan, May Lynn; Holloway, Claire Mb

    2017-05-09

    Timely coordinated diagnostic assessment following an abnormal screening mammogram reduces patient anxiety and may optimise breast cancer prognosis. Since 1998, the Ontario Breast Screening Program (OBSP) has offered organised assessment through Breast Assessment Centres (BACs). For OBSP women seen at a BAC, an abnormal mammogram is followed by coordinated referrals through the use of navigators for further imaging, biopsy, and surgical consultation as indicated. For OBSP women seen through usual care (UC), further diagnostic imaging is arranged directly from the screening centre and/or through their physician; results must be communicated to the physician who is then responsible for arranging any necessary biopsy and/or surgical consultation. This study aims to evaluate factors associated with diagnostic wait times for women undergoing assessment through BAC and UC. Of the 2 147 257 women aged 50-69 years screened in the OBSP between 1 January 2002 and 31 December 2009, 155 866 (7.3%) had an abnormal mammogram. A retrospective design identified two concurrent cohorts of women diagnosed with screen-detected breast cancer at a BAC (n=4217; 47%) and UC (n=4827; 53%). Multivariable logistic regression analyses examined associations between wait times and assessment and prognostic characteristics by pathway. A two-sided 5% significance level was used. Screened women with breast cancer were two times more likely to be diagnosed within 7 weeks when assessed through a BAC vs UC (OR=1.91, 95% CI=1.73-2.10). In addition, compared with UC, women assessed through a BAC were significantly more likely to have their first assessment procedure within 3 weeks of their abnormal mammogram (OR=1.25, 95% CI=1.12-1.39), ⩽3 assessment procedures (OR=1.54, 95% CI=1.41-1.69), ⩽2 assessment visits (OR=1.86, 95% CI=1.70-2.05), and ⩾2 procedures per visit (OR=1.41, 95% CI=1.28-1.55). Women diagnosed through a BAC were also more likely than those in UC to have imaging (OR=1.99, 95

  18. Comparison of clinicoradiologic manifestation of nonspecific interstitial pneumonia and usual interstitial pneumonia/idiopathic pulmonary fibrosis: A report from NRITLD

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    Tafti Saeid

    2008-01-01

    Full Text Available Background: Ever since Katzenstein and Fiorelli introduced the term nonspecific interstitial pneumonia (NSIP to denote those cases of interstitial pneumonia that cannot be categorized as any of the other types of idiopathic interstitial pneumonias (IIP, there has been continuing debate on whether it is a real clinical entity or not. The American Thoracic Society/European Respiratory Symposium task group tried to identify idiopathic NSIP as a separate disease and exclude it from the category of IIP. However, it appears that the clinical presentation of NSIP and usual interstitial pneumonia (UIP are the same. Objective : To show that the radiologic features of NSIP and UIP should be relied upon, instead of clinical presentation and pathologic findings, to differentiate between the two. Materials and Methods: Consecutive patients who had received a diagnosis of either NSIP or UIP on the basis of open lung biopsy between January 2001 and December 2007 were identified for inclusion in this retrospective review. The study included 61 subjects: 32 men and 29 women with a mean age of 59.39 ± 14.5 years. Chest computed tomography images of all the cases were collected for a review. High resolution computed tomography (HRCT and all pathologic specimens were also evaluated. A weighted kappa coefficient was used to evaluate whether radiology can be used instead of biopsy for the diagnosis of NSIP and UIP. Comparison of the mean ages and the time intervals (i.e., interval between symptom onset and the time of diagnosis in the UIP and NSIP groups was done using the Mann-Whitney U test. Association between gender and biopsy result was evaluated by the Fisher exact test. Data were evaluated using SPSS, v.13. Results : Sixty-one patients were included in this study, 32 were male and 29 were female. On the basis of biopsy findings, 50 (82% patients had UIP and 11 (18% had NSIP. Thirty (60% of the 50 patients who had UIP were male and 20 (40% were female; 2 (18

  19. Las complicaciones macrovasculares y su relación con algunas variables clínicas y bioquímicas en diabéticos tipo 2 The macrovascular complications and its relation to some clinical and biochemical variables in type 2 diabetes patients

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    Eduardo Valdés Ramos

    2010-12-01

    Full Text Available OBJETIVO: determinar la frecuencia de macroangiopatía diabética, así como su relación con algunas variables clínicas y bioquímicas en diabéticos tipo 2 (DM 2. MÉTODOS: se realizó un estudio transversal y descriptivo con 438 pacientes DM 2 ingresados en el Centro de Atención al Diabético de Bayamo, Granma, en el período comprendido desde octubre de 2007 a diciembre de 2008. Las variables utilizadas fueron: edad, sexo, color de la piel, consumo de tabaco y alcohol, tiempo de evolución de la diabetes, peso, talla, circunferencia de la cintura, tensión arterial, niveles séricos de colesterol y triglicéridos, así como la presencia de complicaciones macrovasculares de la diabetes. Los sujetos se dividieron en 2 grupos: con macroangiopatía y sin macroangiopatía. RESULTADOS: de los 438 pacientes DM 2 estudiados, 107 (24,4 % tenían algún tipo de macroangiopatía. Predominó la insuficiencia arterial periférica en 67 casos (15,3 %, seguido de la cardiopatía isquémica con 52 (11,8 % y el ictus con 4 (0,9 %. En 16 casos se presentó más de una complicación. Resultó significativa la asociación entre la edad (p=0,0000, el tiempo de evolución de la diabetes (p=0,0000, la hipertensión arterial sistólica (p=0,0361, el colesterol (p=0,0000 y los triglicéridos (p=0,0000, con el desarrollo de macroangiopatía. Los pacientes DM 2 con síndrome metabólico presentaron 4,31 veces más probabilidades de desarrollar cardiopatía isquémica, que aquellos que no lo tenían (p=0,0388. CONCLUSIONES: la frecuencia de complicaciones cardiovasculares en los pacientes con DM 2 en nuestro medio es elevada y se asocia a la edad, el tiempo de evolución de la diabetes, la hipertensión arterial y con los altos niveles de colesterol y triglicéridos. El síndrome metabólico incrementa el riesgo de cardiopatía isquémica en los pacientes con DM 2.OBJETIVE: to determine the diabetic macroangiopathy frequency, as well as its relation to some clinical

  20. Manejo anestésico e complicações no implante percutâneo de válvula aórtica Manejo anestésico y complicaciones en el implante percutáneo de válvula aórtica Anesthetic management and complications of percutaneous aortic valve implantation

    Directory of Open Access Journals (Sweden)

    Tailur Alberto Grando

    2013-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A estenose aórtica (EA grave é uma doença prevalente e de grande mortalidade. Nos pacientes idosos com outras comorbidades o implante valvar percutâneo é uma opção. OBJETIVOS: Descrever o manejo anestésico e as complicações com anestesia geral. MÉTODO: Série de casos com seguimento de 30 dias e 24 meses após o implante do dispositivo CoreValve feito no Instituto de Cardiologia/Fundação Universitária de Cardiologia entre dezembro de 2008 e janeiro de 2012. Os pacientes foram submetidos à anestesia geral monitorada com pressão arterial média (PAM, eletrocardiograma (ECG, oximetria, capnografia, ecocardiograma transesofágico, termometria e marcapasso transvenoso. RESULTADOS: Foram submetidos com sucesso ao implante valvular 28 pacientes, com idade média de 82,46 anos, EuroScore médio de 20,98%, classe funcional III/IV. Nove pacientes necessitaram de implante de marcapasso definitivo. No seguimento dos pacientes houve dois óbitos, um no transoperatório por perfuração do VE e um no terceiro dia por causa desconhecida. Em 24 meses um paciente faleceu com diagnóstico de mieloma múltiplo. A técnica anestésica mostrou-se segura. CONCLUSÃO: A experiência inicial com implante valvular aórtico percutâneo sob anestesia geral tem se mostrado segura e eficaz sem complicações anestésicas importantes para esse procedimento.JUSTIFICATIVA Y OBJETIVOS: La estenosis aórtica (EA grave es una enfermedad prevalente y de gran mortalidad. En los pacientes ancianos con otras comorbilidades, el implante valvular percutáneo es una opción. OBJETIVOS: Describir el manejo anestésico y las complicaciones con la anestesia general. MÉTODO: Serie de casos con seguimiento de 30 días y 24 meses después del implante del dispositivo CoreValve hecho en el Instituto de Cardiología/Fundación Universitaria de Cardiología entre diciembre de 2008 y enero de 2012. Los pacientes fueron sometidos a la anestesia general

  1. Effect of reversal of neuromuscular blockade with sugammadex versus usual care on bleeding risk in a randomized study of surgical patients.

    Science.gov (United States)

    Rahe-Meyer, Niels; Fennema, Hein; Schulman, Sam; Klimscha, Walter; Przemeck, Michael; Blobner, Manfred; Wulf, Hinnerk; Speek, Marcel; McCrary Sisk, Christine; Williams-Herman, Debora; Woo, Tiffany; Szegedi, Armin

    2014-11-01

    Previous studies show a prolongation of activated partial thromboplastin time and prothrombin time in healthy volunteers after treatment with sugammadex. The authors investigated the effect of sugammadex on postsurgical bleeding and coagulation variables. This randomized, double-blind trial enrolled patients receiving thromboprophylaxis and undergoing hip or knee joint replacement or hip fracture surgery. Patients received sugammadex 4 mg/kg or usual care (neostigmine or spontaneous recovery) for reversal of rocuronium- or vecuronium-induced neuromuscular blockade. The Cochran-Mantel-Haenszel method, stratified by thromboprophylaxis and renal status, was used to estimate relative risk and 95% confidence interval (CI) of bleeding events with sugammadex versus usual care. Safety was further evaluated by prespecified endpoints and adverse event reporting. Of 1,198 patients randomized, 1,184 were treated (sugammadex n = 596, usual care n = 588). Bleeding events within 24 h (classified by an independent, blinded Adjudication Committee) were reported in 17 (2.9%) sugammadex and 24 (4.1%) usual care patients (relative risk [95% CI], 0.70 [0.38 to 1.29]). Compared with usual care, increases of 5.5% in activated partial thromboplastin time (P sugammadex occurred 10 min after administration and resolved within 60 min. There were no significant differences between sugammadex and usual care for other blood loss measures (transfusion, 24-h drain volume, drop in hemoglobin, and anemia), or risk of venous thromboembolism, and no cases of anaphylaxis. Sugammadex produced limited, transient (<1 h) increases in activated partial thromboplastin time and prothrombin time but was not associated with increased risk of bleeding versus usual care.

  2. Estimating usual intakes mainly affects the micronutrient distribution among infants, toddlers and pre-schoolers from the 2012 Mexican National Health and Nutrition Survey.

    Science.gov (United States)

    Piernas, Carmen; Miles, Donna R; Deming, Denise M; Reidy, Kathleen C; Popkin, Barry M

    2016-04-01

    To compare estimates from one day with usual intake estimates to evaluate how the adjustment for within-person variability affected nutrient intake and adequacy in Mexican children. In order to obtain usual nutrient intakes, the National Cancer Institute's method was used to correct the first 24 h dietary recall collected in the entire sample (n 2045) with a second 24 h recall collected in a sub-sample (n 178). We computed estimates of one-day and usual intakes of total energy, fat, Fe, Zn and Na. 2012 Mexican National Health and Nutrition Survey. A total of 2045 children were included: 0-5·9 months old (n 182), 6-11·9 months old (n 228), 12-23·9 months old (n 537) and 24-47·9 months old (n 1098). From these, 178 provided an additional dietary recall. Although we found small or no differences in energy intake (kJ/d and kcal/d) between one-day v. usual intake means, the prevalence of inadequate and excessive energy intake decreased somewhat when using measures of usual intake relative to one day. Mean fat intake (g/d) was not different between one-day and usual intake among children >6 months old, but the prevalence of inadequate and excessive fat intake was overestimated among toddlers and pre-schoolers when using one-day intake (P6 months. There was overall low variability in energy and fat intakes but higher for micronutrients. Because the usual intake distributions are narrower, the prevalence of inadequate/excessive intakes may be biased when estimating nutrient adequacy if one day of data is used.

  3. Circulação extracorpórea e complicações no período pós-operatório imediato de cirurgias cardíacas Circulación extracorpórea y complicaciones en el período post-operatorio inmediato de cirugías cardíacas Extracorporeal circulation and complications during the immediate postoperative period for cardiac surgery

    Directory of Open Access Journals (Sweden)

    Fernanda Gaspar Torrati

    2012-01-01

    Full Text Available OBJETIVO: Comparar a frequência de complicações apresentadas pelos pacientes, durante o pós-operatório imediato (POI, de cirurgias cardíacas de acordo com o tempo de circulação extra-corpórea (CEC. MÉTODOS: Estudo de natureza quantitativa, descritivo e correlacional com 83 pacientes adultos divididos em dois grupos de acordo com o tempo de CEC. RESULTADOS: Do total de pacientes, 44 (53% tiveram o tempo de duração da CEC de até 85 minutos e 39 (47 % tiveram o tempo acima de 85 minutos. As complicações foram comuns para ambos os grupos, sendo as mais frequentes dor e oligúria. No entanto, hemotórax, pneumotórax e infarto agudo do miocárdio ocorreram apenas no grupo com maior tempo de CEC. CONCLUSÃO: A maioria das complicações ocorridas no POI apresentou frequencia semelhante para os pacientes, independente do tempo de CEC.OBJETIVO: Comparar la frecuencia de complicaciones presentadas por los pacientes, durante el post-operatorio inmediato (POI, de cirugías cardíacas de acuerdo con el tiempo de circulación extra-corpórea (CEC. MÉTODOS: Estudio de naturaleza cuantitativa, descriptiva y correlacional realizado con 83 pacientes adultos divididos en dos grupos de acuerdo con el tiempo de CEC. RESULTADOS: Del total de pacientes, 44 (53% tuvieron el tiempo de duración de la CEC de hasta 85 minutos y 39 (47 % tuvieron el tempo encima de 85 minutos. Las complicaciones fueron comunes para ambos grupos, siendo las más frecuentes dolor y oliguria. Entre tanto, hemotórax, pneumotórax e infarto agudo del miocardio ocurrieron en el grupo con mayor tiempo de CEC. CONCLUSIÓN: La mayoría de las complicaciones ocurridas en el POI presentó frecuencia semejante para los pacientes, independiente del tiempo de CEC.OBJECTIVE: To compare the frequency of complications presented by patients during the immediate postoperative period (IPP for cardiac surgery, based on the time of extracorporeal circulation (ECC. METHODS: A quantitative

  4. Letalidade e complicações da cirurgia de revascularização miocárdica no Rio de Janeiro, de 1999 a 2003 Letalidad y complicaciones de la cirugía de revascularización miocárdica en el Rio de Janeiro, de 1999 a 2003 Mortality and complications of coronary artery bypass grafting in Rio de Janeiro, from 1999 to 2003

    Directory of Open Access Journals (Sweden)

    Thaís Mendonça Lips de Oliveira

    2010-09-01

    sobreviventes as complicações foram mais frequentes do que o esperado.FUNDAMENTO: La cirugía de revascularización del miocardio (RVM es un procedimiento consolidado en el tratamiento de las enfermedades isquémicas del corazón (EIC, requiriendo constante evaluación. OBJETIVO: Evaluar la calidad en la RVM, a través de las características clínicas de los pacientes, tasas de letalidad hasta un año tras el alta hospitalaria, causas básicas de muerte y complicaciones posoperatorias, en cuatro hospitales públicos del Municipio del Rio de Janeiro, de 1999 a 2003. MÉTODOS: Se seleccionaron aleatoriamente prontuarios de pacientes sometidos a RVM. Informaciones sobre características clínicas, complicaciones y óbitos se recolectaron retrospectivamente de los prontuarios y de las declaraciones de defunción. Las tasas de letalidad se estimaron en los períodos intrahospitalarios y hasta un año posalta. RESULTADOS: Las prevalencias de las características preoperatorias fueron: mujer: Un 31,9%, hipertensión arterial: un 90,7%, dislipidemia: un 67,4%, diabetes: un 37,2%, aquismo: un 22,9%, obesidad: un 18,3%, enfermedad pulmonar obstructiva crónica: un 8,2%, accidente vascular encefálico previo: un 5,8%, arteriopatía extracardíaca: un 12,7%, elevación de la creatinina: un 4,1%, estado crítico preoperatorio: un 3,7%, infarto agudo de miocardio reciente: un 23,5%, angina inestable: un 40,8%, síndrome coronario agudo: el 50%, RVM previa: un 2,4%, disfunción ventricular izquierda: un 27,3%, lesión de tronco da coronaria izquierda: un 3,9% y asociada con lesión en otro sistema: un 19,8%. Las tasas de letalidad en los hospitales variaron del 7% a un 14,3% en el período intrahospitalario y de un 8,5% a un 20,2% hasta un año pos la dada de alta. Las EIC representaron las causas de más del 80% de los óbitos. El grupo de complicaciones posoperatorias más frecuente fue de hemorragia o bajo débito posprocedimiento. Sesenta por ciento de las muertes presentaron cinco o m

  5. Early rehabilitation after total knee replacement surgery: a multicenter, noninferiority, randomized clinical trial comparing a home exercise program with usual outpatient care.

    Science.gov (United States)

    Han, Annie S Y; Nairn, Lillias; Harmer, Alison R; Crosbie, Jack; March, Lyn; Parker, David; Crawford, Ross; Fransen, Marlene

    2015-02-01

    To determine, at 6 weeks postsurgery, if a monitored home exercise program (HEP) is not inferior to usual care rehabilitation for patients undergoing primary unilateral total knee replacement (TKR) surgery for osteoarthritis. We conducted a multicenter, randomized clinical trial. Patients ages 45-75 years were allocated at the time of hospital discharge to usual care rehabilitation (n = 196) or the HEP (n = 194). Outcomes assessed 6 weeks after surgery included the Western Ontario and McMaster Universities Osteoarthritis Index pain and physical function subscales, knee range of motion, and the 50-foot walk time. The upper bound of the 95% confidence interval (95% CI) mean difference favoring usual care was used to determine noninferiority. At 6 weeks after surgery there were no significant differences between usual care and HEP, respectively, for pain (7.4 and 7.2; 95% CI mean difference [MD] -0.7, 0.9), physical function (22.5 and 22.4; 95% CI MD -2.5, 2.6), knee flexion (96° and 97°; 95% CI MD -4°, 2°), knee extension (-7° and -6°; 95% CI MD -2°, 1°), or the 50-foot walk time (12.9 and 12.9 seconds; 95% CI MD -0.8, 0.7 seconds). At 6 weeks, 18 patients (9%) allocated to usual care and 11 (6%) to the HEP did not achieve 80° knee flexion. There was no difference between the treatment allocations in the number of hospital readmissions. The HEP was not inferior to usual care as an early rehabilitation protocol after primary TKR. Copyright © 2015 by the American College of Rheumatology.

  6. Influencia del uso de una técnica menos invasiva que disminuye la aparición de complicaciones de la safenectomía en la cirugía de revascularización miocárdica Influence of the use of a less invasive technique that reduces the appearance of complications of safenectomy in myocardial revascularization surgery

    Directory of Open Access Journals (Sweden)

    José L Ramírez

    2007-12-01

    Full Text Available Introducción: a pesar de sus limitaciones, la vena safena interna aún es el conducto más utilizado en cirugía de revascularización miocárdica. Sin embargo, las complicaciones del procedimiento de extracción de la vena constituyen un problema de gran magnitud en cuanto a morbilidad, estancia hospitalaria y costos de atención. Material y métodos: se presenta un ensayo clínico controlado, en el cual se evalúa una técnica menos invasiva para la extracción de la vena safena interna, en comparación con la técnica estándar de nuestra institución, para lo cual se tomaron 200 pacientes en el grupo de intervención y 400 pacientes en el grupo control. Resultados: la tasa de infección intrahospitalaria de la safenectomía en el grupo de intervención, fue del 0,5% en comparación con el 4% en el grupo control, lo que produce un valor de RR=0,125 con un intervalo de confianza del 95% de 0,016-0,916 sustancialmente menor en el grupo de estudio; el valor de RRA fue de 3,5% y el de NNT fue de 28, lo que indica que con esta técnica se evita una infección en cada 28 pacientes que van a cirugía. Además, se halló que los pacientes del grupo de intervención tienen una estancia hospitalaria significativamente menor que los controles; las medias fueron 7,39 ± 5,882 días para el grupo de intervención y 8,64 ± 8,55 días para el grupo control. Conclusiones: se puede concluir que la técnica de safenectomía menos invasiva es segura, y fácil de aprender, y ofrece una gran ventaja desde el punto de vista de la morbilidad asociada a la herida quirúrgica en las piernas.Background: The internal saphenous vein, despite all its limitations, remains the most used duct for myocardial revascularization. However, the complications regarding the extraction of the vein are a big problem in terms of morbidity, length of hospital stay and costs. Material and methods: We present a controlled clinical assay, evaluating a less invasive technique for

  7. A relação entre polifarmácia, complicações crônicas e depressão em portadores de Diabetes Mellitus Tipo 2 Relación entre polifarmacia, complicaciones crónicas y depresión en portadores de Diabetes Mellitus Tipo 2 The relationship between polipharmacy, chronic complications and depression in individuals with Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Alexandra Bulgarelli do Nascimento

    2010-03-01

    Full Text Available Os objetivos deste estudo foram: caracterizar a polifarmácia entre portadores de Diabetes Mellitus tipo2(DM2; e correlacionar polifarmácia e número de complicações do DM2 com indicadores de depressão (Inventário de Depressão de Beck[IDB] e cortisol urinário[CORT]. A amostra foi composta por 40 pacientes da Liga de Diabetes do HCFM-USP, avaliados quanto aos indicadores de depressão (CORT e IDB e quanto à prática de polifarmácia e número de complicações do DM2. Os resultados mostraram que os medicamentos utilizados foram: antidiabéticos orais, insulinas, anti-hipertensivos, diuréticos, anti-lipêmicos e trombolíticos. No grupo estudado, 75% fizeram uso diário de 5 a 8 medicamentos, e 12,5% de 8 medicamentos/dia ou mais; todos fizeram no mínimo 3 tomadas diárias, 60% tinham entre 1 e 3 complicações do DM2, e 22,5% tinham 3 ou mais. A correlação entre os indicadores de depressão(IDB e CORT, o número de medicamentos e o número de complicações do DM2 não foi estatisticamente significante. No entanto, houve correlação positiva entre CORT e número de tomadas diárias de medicamentos (Spearman,r=0.319, p=0.019.Fueron objetivos de este estudio: caracterizar a la polifarmacia entre portadores de Diabetes Mellitus tipo 2 (DM2 y correlacionar la polifarmacia y el número de complicaciones de la DM2 con indicadores de depresión (Inventario de Depresión de Beck [IDB] y cortisol urinario [CORT]. La muestra fue integrada por 40 pacientes de la Liga de Diabetes del HCFM-USP evaluados respecto de los indicadores de depresión (CORT e IDB y también en cuanto a la práctica de polifarmacia y número de complicaciones de la DM2. Los resultados mostraron que los medicamentos utilizados fueron: antidiabéticos orales, insulinas, antihipertensivos, diuréticos, antilipemiantes y trombolíticos. Dentro del grupo estudiado, 75% de los pacientes utilizaban diariamente entre 5 y 8 medicamentos, un 12,5% de la muestra hacía uso de 8

  8. The 'carry-over' effects of patient self-testing: positive effects on usual care management by an anticoagulation management service.

    LENUS (Irish Health Repository)

    Ryan, Fiona

    2010-11-01

    Patient self-testing (PST) of the international normalised ratio (INR) has a positive effect on anticoagulation control. This study investigated whether the benefits of PST (other than increased frequency of testing, e.g. patient education, empowerment, compliance etc.) could be \\'carried-over\\' into usual care management after a period of home-testing has ceased.

  9. Mindfulness-based stress reduction added to care as usual for lung cancer patients and/or their partners: A multicentre randomized controlled trial

    NARCIS (Netherlands)

    Schellekens, M.P.J.; Hurk, D.G.M. van den; Prins, J.B.; Donders, A.R.T.; Molema, J.; Dekhuijzen, R.; Drift, M.A. van der; Speckens, A.E.M.

    2017-01-01

    OBJECTIVE: Lung cancer patients report among the highest distress rates of all cancer patients. Partners report similar distress rates. The present study examined the effectiveness of additional mindfulness-based stress reduction (care as usual [CAU] + MBSR) versus solely CAU to reduce psychological

  10. Preoperative home-based physical therapy versus usual care to improve functional health of frail older adults scheduled for elective total hip arthroplasty: A pilot randomized controlled trial

    NARCIS (Netherlands)

    Oosting, E.; Jans, M.P.; Dronkers, J.J.; Naber, R.H.; Dronkers-Landman, C.M.; Appelman-De Vries, S.M.; Meeteren, N.L. van

    2012-01-01

    Preoperative home-based physical therapy versus usual care to improve functional health of frail older adults scheduled for elective total hip arthroplasty: a pilot randomized controlled trial. Objective: To investigate the feasibility and preliminary effectiveness of a home-based intensive exercise

  11. Biomarker-based evaluation of two 24-h recalls for comparing usual fish, fruit and vegetable intakes across European centers in the EFCOVAL Study

    NARCIS (Netherlands)

    Vries, de J.H.M.; Crispim, S.P.; Souverein, O.W.; Hulshof, P.J.M.; Ruprich, J.; Dofkova, M.; Huybrechts, I.; Keyzer, de W.; Lillegaard, I.T.L.; Lafay, L.; Rousseau, A.S.; Ocke, M.C.; Slimani, N.; Veer, van 't P.

    2011-01-01

    Background/Objectives: A standardized methodology is important to enable consistent monitoring of dietary intake across European countries. For this reason, we evaluated the comparability of the assessment of usual food intake collected with two non-consecutive computerized 24-h dietary recalls

  12. Cost-effectiveness of cognitive-behavioral therapy versus treatment as usual for anxiety disorders in children with autism spectrum disorder

    NARCIS (Netherlands)

    van Steensel, F.J.A.; Dirksen, C.D.; Bögels, S.M.

    2014-01-01

    The study's aim was to evaluate the cost-effectiveness of CBT compared to treatment as usual (TAU). In total, 49 children aged 8-18 years with ASD and comorbid anxiety disorders, and their parents, participated; 24 were assigned to CBT and 25 were assigned to TAU. Outcome measures were the

  13. Expectations about recovery from acute non-specific low back pain predict absence from usual work due to chronic low back pain : a systematic review

    NARCIS (Netherlands)

    Hallegraeff, J.M.; Krijnen, W.P.; van der Schans, C.P.; de Greef, M.H.G.

    2012-01-01

    Question: Do negative expectations in patients after the onset of acute low back pain increase the odds of absence from usual work due to progression to chronic low back pain? Design: Systematic review with meta-analysis of prospective inception cohort studies. Participants: Adults with acute or

  14. Substitution of Usual Perioperative Care by eHealth to Enhance Postoperative Recovery in Patients Undergoing General Surgical or Gynecological Procedures: Study Protocol of a Randomized Controlled Trial.

    NARCIS (Netherlands)

    Meij, E.; Huirne, J.A.F.; Bouwsma, E.V.A.; van Dongen, J.M.; Terwee, Caroline B; van de Ven, P.M.; Bakker, C.M.; van der Meij, S.; van Baal, W.M.; Leclercq, W.K.G.; Geomini, P.M.; Consten, E.C.; Schraffordt Koops, S.E.; van Kesteren, P.J.; Stockmann, H.B.; Ten Cate, A.D.; Davids, P.H.P.; Scholten, P.C.; van den Heuvel, B.; Schaafsma, Frederieke G.; Meijerink, W.J.; Bonjer, H.J.; Anema, J.R.

    2016-01-01

    BACKGROUND: Due to the strong reduction in the length of hospital stays in the last decade, the period of in-hospital postoperative care is limited. After discharge from the hospital, guidance and monitoring on recovery and resumption of (work) activities are usually not provided. As a consequence,

  15. Cognitive-Behavioral Therapy versus Usual Clinical Care for Youth Depression: An Initial Test of Transportability to Community Clinics and Clinicians

    Science.gov (United States)

    Weisz, John R.; Southam-Gerow, Michael A.; Gordis, Elana B.; Connor-Smith, Jennifer K.; Chu, Brian C.; Langer, David A.; McLeod, Bryce D.; Jensen-Doss, Amanda; Updegraff, Alanna; Weiss, Bahr

    2009-01-01

    Community clinic therapists were randomized to (a) brief training and supervision in cognitive-behavioral therapy (CBT) for youth depression or (b) usual care (UC). The therapists treated 57 youths (56% girls), ages 8-15, of whom 33% were Caucasian, 26% were African American, and 26% were Latino/Latina. Most youths were from low-income families…

  16. Variation in Hospital Length of Stay : Do Physicians Adapt Their Length of Stay Decisions to What Is Usual in the Hospital Where They Work?

    NARCIS (Netherlands)

    Jong, Judith D. de; Westert, Gert P.; Lagoe, Ronald; Groenewegen, Peter P.

    2006-01-01

    Objective. To test the hypothesis that physicianswho work in different hospitals adapt their length of stay decisions to what is usual in the hospital under consideration. Data Sources. Secondary data were used, originating from the Statewide Planning and ResearchCooperative System (SPARCS). SPARCS

  17. Variation in hospital length of stay: do physicians adapt their length of stay decisions to what is usual in the hospital where they work?

    NARCIS (Netherlands)

    Jong, J.D. de; Westert, G.P.; Lagoe, R.; Groenewegen, P.P.

    2006-01-01

    OBJECTIVE: To test the hypothesis that physicians who work in different hospitals adapt their length of stay decisions to what is usual in the hospital under consideration. DATA SOURCES: Secondary data were used, originating from the Statewide Planning and Research Cooperative System (SPARCS).

  18. Effectiveness of rehabilitation after a total hip arthroplasty : A protocol for an observational study for the comparison of usual care in the Netherlands versus Germany

    NARCIS (Netherlands)

    Seeber, Gesine H; Wijnen, Annet; Lazovic, Djordje; Bulstra, Sjoerd K; Dietz, Günter; van Lingen, Christiaan P; Stevens, Martin

    Introduction Osteoarthritis is the most common joint disorder worldwide. Total hip arthroplasty (THA) is considered one of the most effective treatments for end-stage hip osteoarthritis. The number of THAs is expected to increase dramatically in the coming decades. Usual postoperative rehabilitation

  19. The Effect of Cognitive-Behavioral Therapy versus Treatment as Usual for Anxiety in Children with Autism Spectrum Disorders: A Randomized, Controlled Trial

    Science.gov (United States)

    Storch, Eric A.; Arnold, Elysse B.; Lewin, Adam B.; Nadeau, Josh M.; Jones, Anna M.; De Nadai, Alessandro S.; Mutch, P. Jane; Selles, Robert R.; Ung, Danielle; Murphy, Tanya K.

    2013-01-01

    Objective: To examine the efficacy of a modular cognitive-behavioral therapy (CBT) protocol relative to treatment as usual (TAU) among children with high-functioning autism spectrum disorders (ASD) and clinically significant anxiety. Method: A total of 45 children (7-11 years of age) with high-functioning ASD and clinically significant anxiety…

  20. Behavioural graded activity results in better exercise adherence and more physical activity than usual care in people with osteoarthritis: a cluster-randomised trial

    NARCIS (Netherlands)

    Pisters, M.F.; Veenhof, C.; de Bakker, D.H.; Schellevis, F.G.; Dekker, J.

    2010-01-01

    Question: Does behavioural graded activity result in better exercise adherence and more physical activity than usual care in people with osteoarthritis of the hip or knee? Design: Analysis of secondary outcomes of a cluster-randomised trial with concealed allocation, assessor blinding, and

  1. A self-managed single exercise programme versus usual physiotherapy treatment for rotator cuff tendinopathy: a randomised controlled trial (the SELF study).

    Science.gov (United States)

    Littlewood, Chris; Bateman, Marcus; Brown, Kim; Bury, Julie; Mawson, Sue; May, Stephen; Walters, Stephen J

    2016-07-01

    To evaluate the clinical effectiveness of a self-managed single exercise programme versus usual physiotherapy treatment for rotator cuff tendinopathy. Multi-centre pragmatic unblinded parallel group randomised controlled trial. UK National Health Service. Patients with a clinical diagnosis of rotator cuff tendinopathy. The intervention was a programme of self-managed exercise prescribed by a physiotherapist in relation to the most symptomatic shoulder movement. The control group received usual physiotherapy treatment. The primary outcome measure was the Shoulder Pain & Disability Index (SPADI) at three months. Secondary outcomes included the SPADI at six and twelve months. A total of 86 patients (self-managed loaded exercise n=42; usual physiotherapy n=44) were randomised. Twenty-six patients were excluded from the analysis because of lack of primary outcome data at the 3 months follow-up, leaving 60 (n=27; n=33) patients for intention to treat analysis. For the primary outcome, the mean SPADI score at three months was 32.4 (SD 20.2) for the self-managed group, and 30.7 (SD 19.7) for the usual physiotherapy treatment group; mean difference adjusted for baseline score: 3.2 (95% Confidence interval -6.0 to +12.4 P = 0.49).By six and twelve months there remained no significant difference between the groups. This study does not provide sufficient evidence of superiority of one intervention over the other in the short-, mid- or long-term and hence a self-management programme based around a single exercise appears comparable to usual physiotherapy treatment. © The Author(s) 2015.

  2. Effectiveness of Standardized Physical Therapy Exercises for Patients With Difficulty Returning to Usual Activities After Decompression Surgery for Subacromial Impingement Syndrome: Randomized Controlled Trial.

    Science.gov (United States)

    Christiansen, David Høyrup; Frost, Poul; Falla, Deborah; Haahr, Jens Peder; Frich, Lars Henrik; Andrea, Linda Christie; Svendsen, Susanne Wulff

    2016-06-01

    Little is known about the effectiveness of exercise programs after decompression surgery for subacromial impingement syndrome. For patients with difficulty returning to usual activities, special efforts may be needed to improve shoulder function. The purpose of this study was to evaluate the effectiveness at 3 and 12 months of a standardized physical therapy exercise intervention compared with usual care in patients with difficulty returning to usual activities after subacromial decompression surgery. A multicenter randomized controlled trial was conducted. The study was conducted in 6 public departments of orthopedic surgery, 2 departments of occupational medicine, and 2 physical therapy training centers in Central Denmark Region. One hundred twenty-six patients reporting difficulty returning to usual activities at the postoperative clinical follow-up 8 to 12 weeks after subacromial decompression surgery participated. A standardized exercise program consisting of physical therapist-supervised individual training sessions and home training was used. The primary outcome measure was the Oxford Shoulder Score. Secondary outcome measures were the Constant Score and the Fear-Avoidance Beliefs Questionnaire. At 3 and 12 months, follow-up data were obtained for 92% and 83% of the patients, respectively. Intention-to-treat analyses suggested a between-group difference on the Oxford Shoulder Score favoring the exercise group at 3 months, with an adjusted mean difference of 2.0 (95% confidence interval=-0.5, 4.6), and at 12 months, with an adjusted mean difference of 5.8 (95% confidence interval=2.8, 8.9). Significantly larger improvements for the exercise group were observed for most secondary and supplementary outcome measures. The nature of the exercise intervention did not allow blinding of patients and care providers. The standardized physical therapy exercise intervention resulted in statistically significant and clinically relevant improvement in shoulder pain and

  3. Comparison of group-based outpatient physiotherapy with usual care after total knee replacement: a feasibility study for a randomized controlled trial.

    Science.gov (United States)

    Artz, Neil; Dixon, Samantha; Wylde, Vikki; Marques, Elsa; Beswick, Andrew D; Lenguerrand, Erik; Blom, Ashley W; Gooberman-Hill, Rachael

    2017-04-01

    To evaluate the feasibility of conducting a randomized controlled trial comparing group-based outpatient physiotherapy with usual care in patients following total knee replacement. A feasibility study for a randomized controlled trial. One secondary-care hospital orthopaedic centre, Bristol, UK. A total of 46 participants undergoing primary total knee replacement. The intervention group were offered six group-based exercise sessions after surgery. The usual care group received standard postoperative care. Participants were not blinded to group allocation. Feasibility was assessed by recruitment, reasons for non-participation, attendance, and completion rates of study questionnaires that included the Lower Extremity Functional Scale and Knee Injury and Osteoarthritis Outcome Score. Recruitment rate was 37%. Five patients withdrew or were no longer eligible to participate. Intervention attendance was high (73%) and 84% of group participants reported they were 'very satisfied' with the exercises. Return of study questionnaires at six months was lower in the usual care (75%) than in the intervention group (100%). Mean (standard deviation) Lower Extremity Functional Scale scores at six months were 45.0 (20.8) in the usual care and 57.8 (15.2) in the intervention groups. Recruitment and retention of participants in this feasibility study was good. Group-based physiotherapy was acceptable to participants. Questionnaire return rates were lower in the usual care group, but might be enhanced by telephone follow-up. The Lower Extremity Functional Scale had high responsiveness and completion rates. Using this outcome measure, 256 participants would be required in a full-scale randomized controlled trial.

  4. Complicações e seqüelas neurológicas da anestesia regional realizada em crianças sob anestesia geral: um problema real ou casos esporádicos? Complicaciones y secuelas neurológicas de la anestesia regional realizada en niños bajo anestesia general: ¿ Un problema real o casos esporádicos? Neurological complications and damage of regional block in children under general anesthesia: a real problem or sporadic cases?

    Directory of Open Access Journals (Sweden)

    Verônica Vieira da Costa

    2006-12-01

    mayoría de las veces se realiza después de la anestesia general, sea realmente segura. Existe el riesgo potencial de una lesión neurológica permanente o temporal cuando el paciente no puede informar la eventual parestesia o dolor, durante la realización de la anestesia regional, lo que genera inseguridad por parte de los anestesiólogos. El objetivo de este estudio fue el de evaluar la prevalencia de complicaciones y de secuelas neurológicas de la anestesia regional en niños bajo anestesia general. MÉTODO: En un análisis prospectivo se estudiaron niños sometidos a intervenciones quirúrgicas ortopédica y plástica reparadora bajo anestesia regional asociada a la anestesia general. La inducción y el mantenimiento de la anestesia fueron por vía venosa o por inhalación. Después de la anestesia general se realizaba anestesia regional y se evaluaba la existencia de complicaciones inmediatas, el número de punciones realizadas, complicaciones de medio plazo y la presencia de secuelas neurológicas. RESULTADOS: En un período de 13 meses se estudiaron 499 niños de los dos sexos, con edad promedio entre 6 y 7 años. La mayoría de los pacientes se sometió a la anestesia general asociada a la peridural lumbar o caudal. La prevalencia de complicación inmediata fue de un 3,6%, siendo la más frecuente el sangramiento al momento de la punción. La prevalencia de complicaciones en medio plazo fue de un 1,1%, siendo la más frecuente la hipoestesia y no hubo secuela neurológica a largo plazo. CONCLUSIONES: Los resultados del presente estudio están a tono con los de otros autores con relación a la baja prevalencia de complicaciones de la anestesia regional en niños bajo anestesia general, sin dejar secuelas neurológicas. Eso puede ser atribuido al uso de material adecuado y a la experiencia del equipo de anestesia.BACKGROUND AND METHODS: It has been questioned whether regional block in children, which most of the time is done under general anesthesia, is really

  5. Defense bill: Earmarking as usual

    Science.gov (United States)

    Earmarked funds in the $268 billion defense appropriations bill for fiscal year 1991 stirred congressional debate in late October. Senator Sam Nunn (D-Ga.), chairman of the Senate Armed Services Committee, charged that the defense bill contains questionable projects totaling tens of millions of dollars. AGU opposes legislative earmarking of money for particular institutions, maintaining that the practice prevents the best use of federal funding by circumventing competitive review. Nunn noted on the Senate floor that the appropriations bill provided specific funds for cited institutions—contravening a federal law promoting competition. “ If these programs have merit, they will succeed in a fair and competent review in competition,” Nunn said. “If no other institution in the country is able to compete, there should be no fear whatever of competition… But no one else in the world is allowed to compete to work on these projects.”

  6. Rounding up the usual suspects

    DEFF Research Database (Denmark)

    Dimitrov, Dimitar; Benevidas, Ligia R.; Arnedo, Miquel A.

    2017-01-01

    We test the limits of the spider superfamily Araneoidea and reconstruct its interfamilial relationships using standard molecular markers. The taxon sample (363 terminals) comprises for the first time representatives of all araneoid families, including the first molecular data of the family Synaph...

  7. 'Business as usual' in Algeria

    International Nuclear Information System (INIS)

    Hughesman, M.

    1992-01-01

    Reliant on earnings from its oil and gas exports to import food for its growing 25 million population and cope with a $25 billion (bn) foreign debt, Algeria's new 'self-created' government is desperately trying to maintain the country's order. The situation facing Algeria's foreign business partners, notably France and Italy, is discussed. (author)

  8. Usual intake of added sugars and lipid profiles among the U.S. adolescents: National Health and Nutrition Examination Survey, 2005-2010.

    Science.gov (United States)

    Zhang, Zefeng; Gillespie, Cathleen; Welsh, Jean A; Hu, Frank B; Yang, Quanhe

    2015-03-01

    Although studies suggest that higher consumption of added sugars is associated with cardiovascular risk factors in adolescents, none have adjusted for measurement errors or examined its association with the risk of dyslipidemia. We analyzed data of 4,047 adolescents aged 12-19 years from the 2005-2010 National Health and Nutrition Examination Survey, a nationally representative, cross-sectional survey. We estimated the usual percentage of calories (%kcal) from added sugars using up to two 24-hour dietary recalls and the National Cancer Institute method to account for measurement error. The average usual %kcal from added sugars was 16.0%. Most adolescents (88.0%) had usual intake of ≥10% of total energy, and 5.5% had usual intake of ≥25% of total energy. After adjustment for potential confounders, usual %kcal from added sugars was inversely associated with high-density lipoprotein (HDL) and positively associated with triglycerides (TGs), TG-to-HDL ratio, and total cholesterol (TC) to HDL ratio. Comparing the lowest and highest quintiles of intake, HDLs were 49.5 (95% confidence interval [CI], 47.4-51.6) and 46.4 mg/dL (95% CI, 45.2-47.6; p = .009), TGs were 85.6 (95% CI, 75.5-95.6) and 101.2 mg/dL (95% CI, 88.7-113.8; p = .037), TG to HDL ratios were 2.28 (95% CI, 1.84-2.70) and 2.73 (95% CI, 2.11-3.32; p = .017), and TC to HDL ratios were 3.41 (95% CI, 3.03-3.79) and 3.70 (95% CI, 3.24-4.15; p = .028), respectively. Comparing the highest and lowest quintiles of intake, adjusted odds ratio of dyslipidemia was 1.41 (95% CI, 1.01-1.95). The patterns were consistent across sex, race/ethnicity, and body mass index subgroups. No association was found for TC, low-density lipoprotein, and non-HDL cholesterol. Most U.S. adolescents consumed more added sugars than recommended for heart health. Usual intake of added sugars was significantly associated with several measures of lipid profiles. Published by Elsevier Inc.

  9. Randomized clinical trial of an intravenous hydromorphone titration protocol versus usual care for management of acute pain in older emergency department patients.

    Science.gov (United States)

    Chang, Andrew K; Bijur, Polly E; Davitt, Michelle; Gallagher, E John

    2013-09-01

    Opioid titration is an effective strategy for treating pain; however, titration is generally impractical in the busy emergency department (ED) setting. Our objective was to test a rapid, two-step, hydromorphone titration protocol against usual care in older patients presenting to the ED with acute severe pain. This was a prospective, randomized clinical trial of patients 65 years of age and older presenting to an adult, urban, academic ED with acute severe pain. The study was registered at http://www.clinicaltrials.gov (NCT01429285). Patients randomized to the hydromorphone titration protocol initially received 0.5 mg intravenous hydromorphone. Patients randomized to usual care received any dose of any intravenous opioid. At 15 min, patients in both groups were asked, 'Do you want more pain medication?' Patients in the hydromorphone titration group who answered 'yes' received a second dose of 0.5 mg intravenous hydromorphone. Patients in the usual care group who answered 'yes' had their ED attending physician notified, who then could administer any (or no) additional medication. The primary efficacy outcome was satisfactory analgesia defined a priori as the patient declining additional analgesia at least once when asked at 15 or 60 min after administration of the initial opioid. Dose was calculated in morphine equivalent units (MEU: 1 mg hydromorphone = 7 mg morphine). The need for naloxone to reverse adverse opioid effects was the primary safety outcome. 83.0 % of 153 patients in the hydromorphone titration group achieved satisfactory analgesia compared with 82.5 % of 166 patients in the usual care group (p = 0.91). Patients in the hydromorphone titration group received lower mean initial doses of opioids at baseline than patients in the usual care group (3.5 MEU vs. 4.7 MEU, respectively; p ≤ 0.001) and lower total opioids through 60 min (5.3 MEU vs. 6.0 MEU; p = 0.03). No patient needed naloxone. Low-dose titration of intravenous hydromorphone in increments of

  10. Having a usual source of care and its associated factors in Korean adults: a cross-sectional study of the 2012 Korea Health Panel Survey.

    Science.gov (United States)

    An, Ah Reum; Kim, Kyoungwoo; Lee, Jae-Ho; Sung, Nak-Jin; Lee, Sang-Il; Hyun, Min Kyung

    2016-11-29

    Usual source of care (USC) is one of the hallmarks of primary care. We aimed to examine the status of having a USC and its patient-related sociodemographic factors among Korean adults. Data were obtained from the 2012 Korea Health Panel survey. Panel participants were selected for the study who were aged 18 years or older and who replied to questionnaire items on having a USC (n = 11,935). Of the participants, 21.5% had a usual place and 13.9% had a usual physician. Reasons for not having a USC were seldom being ill (66.1%), the preference to visit multiple medical institutions (27.9%), and others. The private community clinic was the most common type of usual place (57.0%). In patient-reported attributes of care provided by a usual physician, the percentages of positive responses for comprehensiveness and coordination were 67.2% and 34.5%, respectively. By institution type, primary care clinics showed the lowest percentage (32.8%) of positive responses for coordination. Adjusted odds ratios of having a usual physician were 3.77 (95% confidence interval, CI: 3.75-3.79) for those aged 65 years or older (vs. aged 18-34 years), 1.31 (CI: 1.30-1.31) for females (vs. males), 0.72 (CI: 0.72-0.73) for unmarried people (vs. married), 1.16 (CI: 1.16-1.16) for college graduates or higher (vs. elementary school graduate or less), 0.64 for the fifth quintile (vs. the first quintile) by household income, 1.53 (CI: 1.52-1.54) for Medical Aid (vs. employee health insurance) for type of health insurance, and 4.09 (CI: 4.08-4.10) for presence (vs. absence) of a chronic diseases. The proportion of Korean adults who have a USC is extremely low, the most influential factor of having a USC is having a chronic disease or not, and Korean patients experience much poorer health care coordination than do patients in other industrialized countries. The findings of this study will give insight to researchers and policy makers regarding the potential facilitators of and barriers to

  11. Usual Intake of Added Sugars and Lipid Profiles Among the U.S. Adolescents: National Health and Nutrition Examination Survey, 2005–2010

    Science.gov (United States)

    Zhang, Zefeng; Gillespie, Cathleen; Welsh, Jean A.; Hu, Frank B.; Yang, Quanhe

    2015-01-01

    Purpose Although studies suggest that higher consumption of added sugars is associated with cardiovascular risk factors in adolescents, none have adjusted for measurement errors or examined its association with the risk of dyslipidemia. Methods We analyzed data of 4,047 adolescents aged 12–19 years from the 2005–2010 National Health and Nutrition Examination Survey, a nationally representative, cross-sectional survey. We estimated the usual percentage of calories (%kcal) from added sugars using up to two 24-hour dietary recalls and the National Cancer Institute method to account for measurement error. Results The average usual %kcal from added sugars was 16.0%. Most adolescents (88.0%) had usual intake of ≥10% of total energy, and 5.5% had usual intake of ≥25% of total energy. After adjustment for potential confounders, usual %kcal from added sugars was inversely associated with high-density lipoprotein (HDL) and positively associated with triglycerides (TGs), TG-to-HDL ratio, and total cholesterol (TC) to HDL ratio. Comparing the lowest and highest quintiles of intake, HDLs were 49.5 (95% confidence interval [CI], 47.4–51.6) and 46.4 mg/dL(95% CI, 45.2–47.6; p = .009), TGs were 85.6 (95% CI, 75.5–95.6) and 101.2 mg/dL(95% CI, 88.7–113.8; p = .037), TG to HDL ratios were 2.28 (95% CI, 1.84–2.70) and 2.73 (95% CI, 2.11–3.32; p = .017), and TC to HDL ratios were 3.41 (95% CI, 3.03–3.79) and 3.70 (95% CI, 3.24–4.15; p = .028), respectively. Comparing the highest and lowest quintiles of intake, adjusted odds ratio of dyslipidemia was 1.41 (95% CI, 1.01–1.95). The patterns were consistent across sex, race/ethnicity, and body mass index subgroups. No association was found for TC, low-density lipoprotein, and non-HDL cholesterol. Conclusions Most U.S. adolescents consumed more added sugars than recommended for heart health. Usual intake of added sugars was significantly associated with several measures of lipid profiles. PMID:25703323

  12. Farmacovigilancia: Una herramienta poco utilizada Pharmacoepidemiology: An unappreciated tool

    Directory of Open Access Journals (Sweden)

    Walter Vasen

    2006-06-01

    Full Text Available La farmacovigilacia es una herramienta esencial para el control de los fármacos utilizados en nuestro país, el presente artículo muestra una revisión de los elementos más destacados en el tema y un resumen de los sistemas regulatorios vigentes en la Argentina y de la experiencia de la Red de Farmacovigilancia de los hospitales del Gobierno de la Ciudad de Buenos Aires, con el objetivo de informar y estimular a los colegas a la denuncia de los efectos adversos de los medicamentos.Pharmacoepidemiology is an essential tool for controlling drugs used in our country. The present article reveals the most relevant aspects on the topic, summarizes regulatory tools currently used in Argentina and explores the experience of the Pharmacoepidemiology Network in public hospitals of Buenos Aires City. The aim is to inform and stimulate colleagues to report adverse effects of drugs.

  13. Tratamiento contra la rabia humana: un poco de su historia

    Directory of Open Access Journals (Sweden)

    Maria Cristina Schneider

    1994-12-01

    Full Text Available El presente trabajo es una revisión histórica del tratamiento utilizado contra la rabia humana, desde la antigüedad hasta el momento actual. Pretende hacer una analogía entre el concepto de causa predominante en la época y el tipo de tratamiento utilizado. Los griegos antiguos tenían la diosa Artemisa como sanadora de la rabia y ya utilizaban la cauterización de la herida. Los pueblos del siglo I conocían la capacidad infecciosa en la saliva de perros rabiosos, llamando a ese material de veneno virus (en latín. En la Edad Media, cuando prevalecía un concepto mágico y religioso de la salud, el gran protector era San Humberto. Con el Renacimiento surgen nuevamente muchos experimentos y avances en el conocimiento de la enfermedad, que sentaron las bases para los importantes hallazgos en el futuro próximo. En esa época predominaba la teoría miasmática y del contagio. Pasteur fue un grande opositor de la espontaneidad de la rabia. A finales del siglo XIX, con los descubrimientos microbianos, Pasteur hizo la gran revolución científica en relación al tratamiento contra la rabia, que es la vacuna. Las vacunas pueden actualmente ser de tipo nervioso o no, variando también el numero de dosis recomendadas. Se han desarrollado muchos estudios sobre vacunas, siendo la más utilizada en América Latina del tipo Fuenzalida y Palacios, y la recomendada actualmente por la OMS es la de cultivo celular.

  14. Tratamiento contra la rabia humana: un poco de su historia

    Directory of Open Access Journals (Sweden)

    Schneider Maria Cristina

    1994-01-01

    Full Text Available El presente trabajo es una revisión histórica del tratamiento utilizado contra la rabia humana, desde la antigüedad hasta el momento actual. Pretende hacer una analogía entre el concepto de causa predominante en la época y el tipo de tratamiento utilizado. Los griegos antiguos tenían la diosa Artemisa como sanadora de la rabia y ya utilizaban la cauterización de la herida. Los pueblos del siglo I conocían la capacidad infecciosa en la saliva de perros rabiosos, llamando a ese material de veneno virus (en latín. En la Edad Media, cuando prevalecía un concepto mágico y religioso de la salud, el gran protector era San Humberto. Con el Renacimiento surgen nuevamente muchos experimentos y avances en el conocimiento de la enfermedad, que sentaron las bases para los importantes hallazgos en el futuro próximo. En esa época predominaba la teoría miasmática y del contagio. Pasteur fue un grande opositor de la espontaneidad de la rabia. A finales del siglo XIX, con los descubrimientos microbianos, Pasteur hizo la gran revolución científica en relación al tratamiento contra la rabia, que es la vacuna. Las vacunas pueden actualmente ser de tipo nervioso o no, variando también el numero de dosis recomendadas. Se han desarrollado muchos estudios sobre vacunas, siendo la más utilizada en América Latina del tipo Fuenzalida y Palacios, y la recomendada actualmente por la OMS es la de cultivo celular.

  15. Wikipedia è poco affidabile? La colpa è anche degli esperti

    Directory of Open Access Journals (Sweden)

    Cristian Cenci

    2017-03-01

    Full Text Available What kind of relationship do the historical sciences have with Wikipedia? How should a reader approach Wikipedia articles dealing with history? What role will the upcoming “free encyclopedia” play in the study and teaching of history? Starting from an analysis on some Wikipedia’s article performed by the “Nicoletta Bourbaki” working group, six authors animate a panel discussion on the relationship between the free encyclopedia and history.

  16. The Pocos de Caldas project feasibility study: 1986-7

    International Nuclear Information System (INIS)

    Smellie, J.A.T.; Chapman, N.A.; Franca, E.P.

    1987-01-01

    This paper presents feasibility studies to investigate the uranium, thorium and rare earth deposits, in Morro do Ferro and the uranium mine in Osamu Utsumi, Brazil, as natural analogues to link rock geochemistry and hydrogeological systems to assess radionuclide mobility. Ore samples were analysed to obtain uranium concentrations and hydraulic tests were carried out. (UK)

  17. Well safety in Brazil; Seguranca de poco no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Otto L.A.; Sotomayor, Gabriel P.G.; Lage, Antonio C.M.; Scaringi Filho, Orlando; Martins, Francisco S.B. [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2004-07-01

    This article presents and discusses the actions taken in Brazil, in order to make drilling, completion and intervention operations safer. The implementation of these actions resulted in a reduction of the number of blowouts in the Country. They can be grouped into four categories: training and certification in well control of all personnel directly involved in drilling, completion and intervention operations (so far, more than 3800 well control certificates have been issued since the beginning of the certification program in 1993); rig inspections of the well control equipment and procedures and follow-up of the well control drills and rig crew certification; development of a program for writing regulations for several well control aspects such as design and operational procedures, equipment requirements, and practical recommendations for well control operations; and well control research projects specially those focused on deep waters. (author)

  18. Mastocitosis: Unaafección poco común

    OpenAIRE

    Coronel Carbajal, Carlos

    2001-01-01

    La mastocitosis es la proliferación anormal de mastocitos que puede afectar 1 o varios órganos. Esta célula almacena importantes sustancias farmacológicamente activas. Sus manifestaciones más frecuentes son las cutáneas, pero pueden aparecer otras a causa de afectación de órganos como la médula ósea, hígado, bazo, huesos, ganglios linfáticos y tubo digestivo. Existen varios métodos diagnósticos, pero la histología es fundamental. El tratamiento incluye medidas generales y específicas; actualm...

  19. Mastocitosis: Unaafección poco común

    Directory of Open Access Journals (Sweden)

    Carlos Coronel Carbajal

    2001-06-01

    Full Text Available La mastocitosis es la proliferación anormal de mastocitos que puede afectar 1 o varios órganos. Esta célula almacena importantes sustancias farmacológicamente activas. Sus manifestaciones más frecuentes son las cutáneas, pero pueden aparecer otras a causa de afectación de órganos como la médula ósea, hígado, bazo, huesos, ganglios linfáticos y tubo digestivo. Existen varios métodos diagnósticos, pero la histología es fundamental. El tratamiento incluye medidas generales y específicas; actualmente el uso del interferón ha cobrado interés.Mastocytosis is the abnormal proliferation of mastocytes that may affect one or various organs. This cell stores important pharmacologically active substances. Its most frequent manifestations are the cutaneous ones, but other manifestations may appear as a result of the affectation of some organs as the bone marow, the liver, the spleen, the bones, the lymphatic ganglia and the digestive tube. There are different diagnostic methods, but histology is essential. The treatment includes general and specific measures. Interest in using interferon has increased nowadays.

  20. Management of uncomplicated malaria in children under 13 years of age at a district hospital in senegal : from official guidelines to usual practices

    OpenAIRE

    Sarrassat, Sophie; Lalou, Richard; Cisse, M.; Le Hesran, Jean-Yves

    2011-01-01

    Abstract Background To be effective, national malaria guidelines must be properly followed. This study evaluated nurses' practices in the management of uncomplicated malaria cases at a District Hospital. Its objective was to identify the reasons for discrepancies between official guidelines and usual practices. Methods This study took place at Oussouye hospital, south-western Senegal. Blood smears were available for biological diagnosis in patients aged more than five years while the Integrat...

  1. Young Adult and Usual Adult Body Mass Index and Multiple Myeloma Risk: A Pooled Analysis in the International Multiple Myeloma Consortium (IMMC).

    Science.gov (United States)

    Birmann, Brenda M; Andreotti, Gabriella; De Roos, Anneclaire J; Camp, Nicola J; Chiu, Brian C H; Spinelli, John J; Becker, Nikolaus; Benhaim-Luzon, Véronique; Bhatti, Parveen; Boffetta, Paolo; Brennan, Paul; Brown, Elizabeth E; Cocco, Pierluigi; Costas, Laura; Cozen, Wendy; de Sanjosé, Silvia; Foretová, Lenka; Giles, Graham G; Maynadié, Marc; Moysich, Kirsten; Nieters, Alexandra; Staines, Anthony; Tricot, Guido; Weisenburger, Dennis; Zhang, Yawei; Baris, Dalsu; Purdue, Mark P

    2017-06-01

    Background: Multiple myeloma risk increases with higher adult body mass index (BMI). Emerging evidence also supports an association of young adult BMI with multiple myeloma. We undertook a pooled analysis of eight case-control studies to further evaluate anthropometric multiple myeloma risk factors, including young adult BMI. Methods: We conducted multivariable logistic regression analysis of usual adult anthropometric measures of 2,318 multiple myeloma cases and 9,609 controls, and of young adult BMI (age 25 or 30 years) for 1,164 cases and 3,629 controls. Results: In the pooled sample, multiple myeloma risk was positively associated with usual adult BMI; risk increased 9% per 5-kg/m 2 increase in BMI [OR, 1.09; 95% confidence interval (CI), 1.04-1.14; P = 0.007]. We observed significant heterogeneity by study design ( P = 0.04), noting the BMI-multiple myeloma association only for population-based studies ( P trend = 0.0003). Young adult BMI was also positively associated with multiple myeloma (per 5-kg/m 2 ; OR, 1.2; 95% CI, 1.1-1.3; P = 0.0002). Furthermore, we observed strong evidence of interaction between younger and usual adult BMI ( P interaction adult BMI may increase multiple myeloma risk and suggest that healthy BMI maintenance throughout life may confer an added benefit of multiple myeloma prevention. Cancer Epidemiol Biomarkers Prev; 26(6); 876-85. ©2017 AACR . ©2017 American Association for Cancer Research.

  2. Gaussian Quadrature is an efficient method for the back-transformation in estimating the usual intake distribution when assessing dietary exposure.

    Science.gov (United States)

    Dekkers, A L M; Slob, W

    2012-10-01

    In dietary exposure assessment, statistical methods exist for estimating the usual intake distribution from daily intake data. These methods transform the dietary intake data to normal observations, eliminate the within-person variance, and then back-transform the data to the original scale. We propose Gaussian Quadrature (GQ), a numerical integration method, as an efficient way of back-transformation. We compare GQ with six published methods. One method uses a log-transformation, while the other methods, including GQ, use a Box-Cox transformation. This study shows that, for various parameter choices, the methods with a Box-Cox transformation estimate the theoretical usual intake distributions quite well, although one method, a Taylor approximation, is less accurate. Two applications--on folate intake and fruit consumption--confirmed these results. In one extreme case, some methods, including GQ, could not be applied for low percentiles. We solved this problem by modifying GQ. One method is based on the assumption that the daily intakes are log-normally distributed. Even if this condition is not fulfilled, the log-transformation performs well as long as the within-individual variance is small compared to the mean. We conclude that the modified GQ is an efficient, fast and accurate method for estimating the usual intake distribution. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Nutrient intakes among children and adolescents eating usual pizza products in school lunch compared with pizza meeting HealthierUS School Challenge criteria.

    Science.gov (United States)

    Hur, In Young; Marquart, Len; Reicks, Marla

    2014-05-01

    Pizza is a popular food that can contribute to high intakes of saturated fat and sodium among children and adolescents. The objective of this study was to compare daily nutrient intakes when a pizza product meeting the US Department of Agriculture's criteria for competitive food entrées under the HealthierUS School Challenge (HUSSC) was substituted for usual pizza products consumed during foodservice-prepared school lunch. The study used National Health and Nutrition Examination Survey (2005-2008) dietary recall data from a cross-sectional sample of US children and adolescents (age 5 to 18 years, n=337) who ate pizza during school lunch on 1 day of dietary recall. Daily nutrient intakes based on the consumption of usual pizza products for school lunch (pre-modeled) were compared with intakes modeled by substituting nutrient values from an HUSSC whole-grain pizza product (post-modeled). Paired t tests were used to make the comparison. Post-modeled intakes were lower in daily energy, carbohydrate, total fat, saturated fat, cholesterol, and sodium compared with pre-modeled intakes among children and adolescents (Ppizza product for usual pizza products may significantly improve dietary quality of children and adolescents eating pizza for school lunch, indicating that it could be an effective approach to improve the nutritional quality of school lunch programs. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  4. Dissemination of the nurse-administered Tobacco Tactics intervention versus usual care in six Trinity community hospitals: study protocol for a comparative effectiveness trial

    Directory of Open Access Journals (Sweden)

    Duffy Sonia A

    2012-08-01

    Full Text Available Abstract Background The objectives of this smoking cessation study among hospitalized smokers are to: 1 determine provider and patient receptivity, barriers, and facilitators to implementing the nurse-administered, inpatient Tobacco Tactics intervention versus usual care using face-to-face feedback and surveys; 2 compare the effectiveness of the nurse-administered, inpatient Tobacco Tactics intervention versus usual care across hospitals, units, and patient characteristics using thirty-day point prevalence abstinence at thirty days and six months (primary outcome post-recruitment; and 3 determine the cost-effectiveness of the nurse-administered, inpatient Tobacco Tactics intervention relative to usual care including cost per quitter, cost per life-year saved, and cost per quality-adjusted life-year saved. Methods/Design This effectiveness study will be a quasi-experimental design of six Michigan community hospitals of which three will get the nurse-administered Tobacco Tactics intervention and three will provide their usual care. In both the intervention and usual care sites, research assistants will collect data from patients on their smoking habits and related variables while in the hospital and at thirty days and six months post-recruitment. The intervention will be integrated into the experimental sites by a research nurse who will train Master Trainers at each intervention site. The Master Trainers, in turn, will teach the intervention to all staff nurses. Research nurses will also conduct formative evaluation with nurses to identify barriers and facilitators to dissemination. Descriptive statistics will be used to summarize the results of surveys administered to nurses, nurses’ participation rates, smokers’ receipt of specific cessation services, and satisfaction with services. General estimating equation analyses will be used to determine differences between intervention groups on satisfaction and quit rates, respectively, with

  5. Estimating the population distribution of usual 24-hour sodium excretion from timed urine void specimens using a statistical approach accounting for correlated measurement errors.

    Science.gov (United States)

    Wang, Chia-Yih; Carriquiry, Alicia L; Chen, Te-Ching; Loria, Catherine M; Pfeiffer, Christine M; Liu, Kiang; Sempos, Christopher T; Perrine, Cria G; Cogswell, Mary E

    2015-05-01

    High US sodium intake and national reduction efforts necessitate developing a feasible and valid monitoring method across the distribution of low-to-high sodium intake. We examined a statistical approach using timed urine voids to estimate the population distribution of usual 24-h sodium excretion. A sample of 407 adults, aged 18-39 y (54% female, 48% black), collected each void in a separate container for 24 h; 133 repeated the procedure 4-11 d later. Four timed voids (morning, afternoon, evening, overnight) were selected from each 24-h collection. We developed gender-specific equations to calibrate total sodium excreted in each of the one-void (e.g., morning) and combined two-void (e.g., morning + afternoon) urines to 24-h sodium excretion. The calibrated sodium excretions were used to estimate the population distribution of usual 24-h sodium excretion. Participants were then randomly assigned to modeling (n = 160) or validation (n = 247) groups to examine the bias in estimated population percentiles. Median bias in predicting selected percentiles (5th, 25th, 50th, 75th, 95th) of usual 24-h sodium excretion with one-void urines ranged from -367 to 284 mg (-7.7 to 12.2% of the observed usual excretions) for men and -604 to 486 mg (-14.6 to 23.7%) for women, and with two-void urines from -338 to 263 mg (-6.9 to 10.4%) and -166 to 153 mg (-4.1 to 8.1%), respectively. Four of the 6 two-void urine combinations produced no significant bias in predicting selected percentiles. Our approach to estimate the population usual 24-h sodium excretion, which uses calibrated timed-void sodium to account for day-to-day variation and covariance between measurement errors, produced percentile estimates with relatively low biases across low-to-high sodium excretions. This may provide a low-burden, low-cost alternative to 24-h collections in monitoring population sodium intake among healthy young adults and merits further investigation in other population subgroups. © 2015 American

  6. Focal psychodynamic therapy, cognitive behaviour therapy, and optimised treatment as usual in outpatients with anorexia nervosa (ANTOP study): randomised controlled trial.

    Science.gov (United States)

    Zipfel, Stephan; Wild, Beate; Groß, Gaby; Friederich, Hans-Christoph; Teufel, Martin; Schellberg, Dieter; Giel, Katrin E; de Zwaan, Martina; Dinkel, Andreas; Herpertz, Stephan; Burgmer, Markus; Löwe, Bernd; Tagay, Sefik; von Wietersheim, Jörn; Zeeck, Almut; Schade-Brittinger, Carmen; Schauenburg, Henning; Herzog, Wolfgang

    2014-01-11

    Psychotherapy is the treatment of choice for patients with anorexia nervosa, although evidence of efficacy is weak. The Anorexia Nervosa Treatment of OutPatients (ANTOP) study aimed to assess the efficacy and safety of two manual-based outpatient treatments for anorexia nervosa--focal psychodynamic therapy and enhanced cognitive behaviour therapy--versus optimised treatment as usual. The ANTOP study is a multicentre, randomised controlled efficacy trial in adults with anorexia nervosa. We recruited patients from ten university hospitals in Germany. Participants were randomly allocated to 10 months of treatment with either focal psychodynamic therapy, enhanced cognitive behaviour therapy, or optimised treatment as usual (including outpatient psychotherapy and structured care from a family doctor). The primary outcome was weight gain, measured as increased body-mass index (BMI) at the end of treatment. A key secondary outcome was rate of recovery (based on a combination of weight gain and eating disorder-specific psychopathology). Analysis was by intention to treat. This trial is registered at http://isrctn.org, number ISRCTN72809357. Of 727 adults screened for inclusion, 242 underwent randomisation: 80 to focal psychodynamic therapy, 80 to enhanced cognitive behaviour therapy, and 82 to optimised treatment as usual. At the end of treatment, 54 patients (22%) were lost to follow-up, and at 12-month follow-up a total of 73 (30%) had dropped out. At the end of treatment, BMI had increased in all study groups (focal psychodynamic therapy 0·73 kg/m(2), enhanced cognitive behaviour therapy 0·93 kg/m(2), optimised treatment as usual 0·69 kg/m(2)); no differences were noted between groups (mean difference between focal psychodynamic therapy and enhanced cognitive behaviour therapy -0·45, 95% CI -0·96 to 0·07; focal psychodynamic therapy vs optimised treatment as usual -0·14, -0·68 to 0·39; enhanced cognitive behaviour therapy vs optimised treatment as usual -0·30

  7. Evaluación del proyecto estatal de intervención para la mejora de la calidad de vida y la reducción de complicaciones asociadas al envejecimiento: «Agrega salud a tus años» Evaluation of the state intervention project to improve quality of life and reduce the complications associated with aging: "Add health to your years"

    Directory of Open Access Journals (Sweden)

    Gustavo Horacio Marín

    2009-08-01

    Full Text Available Objetivo: Evaluar la eficacia de un programa de promoción de salud y prevención de patologías asociadas al envejecimiento, para evitar complicaciones asociadas y mejorar la calidad de vida en adultos mayores. Metodología: Estudio desarrollado durante 12 meses (años 2006-2007 en 700 adultos mayores de Buenos Aires-Argentina, separados de forma aleatoria en 2 grupos: intervención y control. A todos se les realizaron mediciones pre y postintervención de peso, talla, tensión arterial, colesterol, triglicéridos, glucemia y problemas cardiovasculares (infarto, accidente vascular cerebral, osteoarticulares (fracturas, ingresos hospitalarios y calidad de vida evaluada con la Encuesta-SF12. La intervención consistió en actividad física periódica (bisemanal destinada a fortalecer grupos musculares que otorgan autonomía de movimientos, así como actividades recreativas, talleres de nutrición y manipulación de alimentos. A cada individuo del grupo intervención se le asignó un estudiante de medicina que semanalmente lo visitó y acompañó en las actividades. El grupo control continuó con actividades habituales. Resultados: El grupo de intervención mostró una reducción significativa en valores de tensión arterial, triglicéridos y colesterol respecto al control. Además, redujo un 31% los eventos cardiovasculares, 18,2% las fracturas de cadera, 21,1% los ingresos hospitalarios por problemas cardiovasculares, osteoarticulares y de salud mental respecto al control. La encuesta de calidad de vida postintervención incrementó un 28,7% las respuestas favorables respecto su registro basal y 33,4% respecto al grupo control. Conclusión: El programa implementado logró reducir los factores de riesgo y las complicaciones asociadas al envejecimiento en el grupo de intervención respecto al control.Objective: This paper evaluates the effectiveness of a Public Health program for the elderly based on health promotion and pathologies prevention, in

  8. Transporte intra-hospitalar de pacientes adultos em estado crítico: complicações relacionadas à equipe, equipamentos e fatores fisiológicos Transporte intrahospitalario de pacientes adultos en estado crítico: complicaciones relacionadas al equipo, equipamientos y factores fisiológicos Intra-hospital transport of critically ill adult patients: complications related to staff, equipment and physiological factors

    Directory of Open Access Journals (Sweden)

    Ana Carolina Goulardins de Almeida

    2012-01-01

    Full Text Available OBJETIVO: Identificar na literatura as complicações relacionadas às alterações fisiológicas do paciente, à equipe multidisciplinar e ao uso de equipamentos durante o transporte intra-hospitalar de pacientes críticos. MÉTODOS: Revisão integrativa da literatura, com busca nas bases de dados PUBMED, MEDLINE, e LILACS. RESULTADOS: Foram encontrados 20 artigos, todos escritos na língua inglesa. Os estudos mostraram que as alterações na pressão arterial e na frequência cardíaca são as mais comuns durante o transporte. Dos eventos adversos relacionados a problemas com a equipe, destacaram-se, a falta de conhecimento do profissional e a falha de comunicação, além dos provenientes dos equipamentos utilizados. CONCLUSÃO: Transportar o paciente crítico de maneira segura significa melhorar a comunicação entre as equipes, padronizar as ações e equipamentos utilizados por meio de protocolos e identificar intercorrências para obter excelência no atendimento durante o transporte.OBJETIVO: Identificar en la literatura las complicaciones relacionadas a las alteraciones fisiológicas del paciente, al equipo multidisciplinario y al uso de equipamientos durante el transporte intrahospitalario de pacientes críticos. MÉTODOS: Revisión integrativa de la literatura, con búsqueda en las bases de datos PUBMED, MEDLINE, y LILACS. RESULTADOS: Fueron encontrados 20 artículos, todos escritos en el idioma inglés. Los estudios mostraron que las alteraciones en la presión arterial y en la frecuencia cardíaca son las más comunes durante el transporte. De los eventos adversos relacionados a problemas con el equipo, se destacaron, la falta de conocimiento del profesional y la falla en la comunicación, además de los provenientes de los equipamientos utilizados. CONCLUSIÓN: Transportar al paciente crítico de manera segura significa mejorar la comunicación entre los equipos, patronizar las acciones y equipamientos utilizados por medio de

  9. Perfil das crianças submetidas à correção de cardiopatia congênita e análise das complicações respiratórias Perfil de los niños sometidos a la corrección de cardiopatía congénita y análisis de las complicaciones respiratorias Profile of children undergoing congenital heart surgery and analysis of their respiratory complications

    Directory of Open Access Journals (Sweden)

    Priscila Mara N. Oliveira

    2012-01-01

    Full Text Available OBJETIVO: Descrever as características demográficas e clínicas de crianças submetidas à cirurgia de correção de cardiopatia congênita (CC em um hospital universitário, comparando pacientes com e sem complicações respiratórias no pós-operatório. MÉTODOS: Estudo retrospectivo, realizado por meio de consulta de prontuários de crianças submetidas à cirurgia corretiva de CC em hospital universitário brasileiro no período de novembro de 2006 a setembro de 2007. Foram analisados dados relativos a idade, sexo, peso, comorbidades e tipo de CC das crianças incluídas no estudo, comparando pacientes com e sem complicações respiratórias no pós-operatório. Foram utilizados o teste de Mann-Whitney e exato de Fisher, considerando-se significante pOBJETIVO: Describir las características demográficas y clínicas de niños sometidos a la cirugía de corrección de cardiopatía congénita (CC en un hospital universitario, comparando pacientes con y sin complicaciones respiratorias en el post-operatorio. MÉTODOS: Estudio retrospectivo, realizado por medio de consulta de prontuarios de niños sometidos a la cirugía correctiva de CC, en el Hospital de Clínicas de la Universidad Estadual de Campinas (Unicamp, en el periodo de noviembre de 2006 a septiembre de 2007. Se analizaron datos relativos a la edad, sexo, peso, comorbidades y tipo de CC de los niños incluidos en el estudio, comparando pacientes con y sin complicaciones respiratorias en el post-operatorio. Se utilizaron el test de Mann-Whitney y el exacto de Fisher, considerándose significante pOBJECTIVE: To describe the profile of children that undergo surgical correction of congenital heart disease (CHD in a university hospital and to compare patients with and without postoperative respiratory complications. METHOD: This observational analytical study reviewed the records of children that underwent corrective surgery for CHD a Brazilian University Hospital during 11 months. The

  10. Tratamento cirúrgico da escoliose em pacientes com amiotrofia espinhal com parafusos pediculares (instrumental de 3ª geração e complicações precoces Tratamiento quirúrgico de la escoliosis en pacientes con amiotrofia espinal con tornillos pediculares (instrumental de 3ª generación y complicaciones precoces Surgical treatment of scoliosis in spinal muscular atrophy with pedicle screws (third generation instrumentation and early complications

    Directory of Open Access Journals (Sweden)

    Daniel Cantarelli dos Santos

    2010-06-01

    Full Text Available OBJETIVO: avaliar a utilização de artrodese via posterior com parafusos pediculares para correção da escoliose em pacientes com amiotrofia espinhal. MÉTODOS: realizou-se um estudo retrospectivo de 16 pacientes com amiotrofia espinhal submetidos à artrodese via posterior exclusiva, com parafusos pediculares. Foi avaliado o perfil geral dos pacientes e o potencial de correção do ângulo de Cobb e da obliquidade pélvica, além das complicações precoces. RESULTADOS: o ângulo de Cobb pré-operatório foi em média de 94,6º (65 a 132º, no pós-operatório de 40,4º (2 a 70º, percentual de correção de 57,2%. A obliquidade pélvica pré-operatória foi em média 34,7º (25 a 56º, no pós-operatório foi para 11,3º (0 a 20º, com percentual de correção de 67,4%. Cinco pacientes tiveram complicações precoces (31,2% com boa resolução. CONCLUSÕES: o tratamento cirúrgico da escoliose em pacientes com amiotrofia espinhal por meio de artrodese via posterior utilizando parafusos pediculares tem grande potencial de correção da deformidade coronal e da obliquidade pélvica, sem grandes complicações no pós-operatório precoce.OBJETIVO: evaluar la utilización de la artrodesis vía posterior con tornillos pediculares para la corrección de la escoliosis en pacientes con amiotrofia espinal. MÉTODOS: fue realizado un estudio retrospectivo de 16 pacientes con amiotrofia espinal sometidos a la artrodesis vía posterior exclusiva, con tornillos pediculares. Fue evaluado el perfil general de los pacientes, y el potencial de corrección del ángulo de Cobb y de la oblicuidad pélvica, además de las complicaciones precoces. RESULTADOS: el ángulo de Cobb preoperatorio fue en promedio 94.6º (65 a 132º, en el postoperatorio 40.4º (2 a 70, porcentual de corrección de 57.2%. La oblicuidad pélvica preoperatoria fue en media 34.7º (25 a 56º, en el postoperatorio fue para 11.3º (0 a 20º, porcentual de corrección de 67.4%. Cinco

  11. Effects of structured versus usual care on renal endpoint in type 2 diabetes: the SURE study: a randomized multicenter translational study.

    Science.gov (United States)

    Chan, Juliana C; So, Wing-Yee; Yeung, Chun-Yip; Ko, Gary T; Lau, Ip-Tim; Tsang, Man-Wo; Lau, Kam-Piu; Siu, Sing-Chung; Li, June K; Yeung, Vincent T; Leung, Wilson Y; Tong, Peter C

    2009-06-01

    Multifaceted care has been shown to reduce mortality and complications in type 2 diabetes. We hypothesized that structured care would reduce renal complications in type 2 diabetes. A total of 205 Chinese type 2 diabetic patients from nine public hospitals who had plasma creatinine levels of 150-350 micromol/l were randomly assigned to receive structured care (n = 104) or usual care (n = 101) for 2 years. The structured care group was managed according to a prespecified protocol with the following treatment goals: blood pressure triglyceride 500 micromol/l or dialysis). Of these 205 patients (mean +/- SD age 65 +/- 7.2 years; disease duration 14 +/- 7.9 years), the structured care group achieved better control than the usual care group (diastolic blood pressure 68 +/- 12 vs. 71 +/- 12 mmHg, respectively, P = 0.02; A1C 7.3 +/- 1.3 vs. 8.0 +/- 1.6%, P structured care (23.1%, n = 24) and usual care (23.8%, n = 24; NS) groups had similar end points, but more patients in the structured care group attained >or=3 treatment goals (61%, n = 63, vs. 28%, n = 28; P or=3 treatment targets (n = 91) had reduced risk of the primary end point (14 vs. 34; relative risk 0.43 [95% CI 0.21-0.86] compared with that of those who attained

  12. Encounter Decision Aid vs. Clinical Decision Support or Usual Care to Support Patient-Centered Treatment Decisions in Osteoporosis: The Osteoporosis Choice Randomized Trial II.

    Directory of Open Access Journals (Sweden)

    Annie LeBlanc

    Full Text Available Osteoporosis Choice, an encounter decision aid, can engage patients and clinicians in shared decision making about osteoporosis treatment. Its effectiveness compared to the routine provision to clinicians of the patient's estimated risk of fracture using the FRAX calculator is unknown.Patient-level, randomized, three-arm trial enrolling women over 50 with osteopenia or osteoporosis eligible for treatment with bisphosphonates, where the use of Osteoporosis Choice was compared to FRAX only and to usual care to determine impact on patient knowledge, decisional conflict, involvement in the decision-making process, decision to start and adherence to bisphosphonates.We enrolled 79 women in the three arms. Because FRAX estimation alone and usual care produced similar results, we grouped them for analysis. Compared to these, use of Osteoporosis Choice increased patient knowledge (median score 6 vs. 4, p = .01, improved understanding of fracture risk and risk reduction with bisphosphonates (p = .01 and p<.0001, respectively, had no effect on decision conflict, and increased patient engagement in the decision making process (OPTION scores 57% vs. 43%, p = .001. Encounters with the decision aid were 0.8 minutes longer (range: 33 minutes shorter to 3.0 minutes longer. There were twice as many patients receiving and filling prescriptions in the decision aid arm (83% vs. 40%, p = .07; medication adherence at 6 months was no different across arms.Supporting both patients and clinicians during the clinical encounter with the Osteoporosis Choice decision aid efficiently improves treatment decision making when compared to usual care with or without clinical decision support with FRAX results.clinical trials.gov NCT00949611.

  13. Effect of nurse home visits vs. usual care on reducing intimate partner violence in young high-risk pregnant women: a randomized controlled trial.

    Science.gov (United States)

    Mejdoubi, Jamila; van den Heijkant, Silvia C C M; van Leerdam, Frank J M; Heymans, Martijn W; Hirasing, Remy A; Crijnen, Alfons A M

    2013-01-01

    Expectant mothers and mothers of young children are especially vulnerable to intimate partner violence (IPV). The nurse-family partnership (NFP) is a home visitation program in the United States effective for the prevention of adverse child health outcomes. Evidence regarding the effect of nurse home visiting on IPV is inconsistent. This study aims to study the effect of VoorZorg, the Dutch NFP, on IPV. A random sample of 460 eligible disadvantaged women births, was randomized. Women in the control group (C; n=223) received usual care; women in the intervention group (I; n=237) received usual care plus nurse home visits periodically during pregnancy and until the child's second birthday. At 32 weeks of pregnancy, women in the intervention group self-reported significantly less IPV victimization than women in the control group in: level 2 psychological aggression (C: 56% vs. I: 39%), physical assault level 1 (C: 58% vs. I: 40%) and level 2 (C: 31% vs. I: 20%), and level 1 sexual coercion (C: 16% vs. I: 8%). Furthermore, women in the intervention group reported significantly less IPV perpetration in: level 2 psychological aggression (C: 60% vs. I: 46%), level 1 physical assault (C: 65% vs. I: 52%), and level 1 injury (C: 27% vs. I: 17%). At 24 months after birth, IPV victimization was significantly lower in the intervention group for level 1 physical assault (C: 44% vs. I: 26%), and IPV perpetration was significantly lower for level 1 sexual assault (C: 18% vs. I: 3%). Multilevel analyses showed a significant improvement in IPV victimization and perpetration among women in the intervention group at 24 months after birth. VoorZorg, compared with the usual care, is effective in reducing IPV during pregnancy and in the two years after birth among young high-risk women. Dutch Trial Register NTR854 http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=854.

  14. South Africa's greenhouse gas emissions under business-as-usual: The technical basis of 'Growth without Constraints' in the Long-Term Mitigation Scenarios

    International Nuclear Information System (INIS)

    Winkler, Harald; Hughes, Alison; Marquard, Andrew; Haw, Mary; Merven, Bruno

    2011-01-01

    This article describes the methodology for projecting business-as-usual GHG trajectory developed in technical work for South Africa's Long-Term Mitigation Scenarios (LTMSs), in particular the 'Growth without Constraints' (GWCs) scenario. Technically rigorous projections are important as developing countries define their commitment to act on mitigation relative to business-as-usual (BAU). The key drivers for the GWC scenario include GDP (both growth rate and composition), population, discount rate and technological change. GDP emerged as an important driver in the research for LTMS and further analysis. If South Africa's economy grows without constraints over the next few decades, GHG emissions will continue to escalate, multiplying more than four-fold by mid-century. There is little gain in energy efficiency, and emissions continue to be dominated by energy use and supply, the latter remaining coal-based in GWC. We analyse the projections (not predictions) in relation to various measures. The LTMS GWC scenario is compared to other projections, nationally and internationally. A broadly comparable projection is being used at national level, for electricity planning. When compared to projections from international models, we find that the assumptions about GDP growth rates are a key factor, and suggest that comparisons of global data-sets against national analyses is important. - Highlights: → Specifies business-as-usual GHG trajectory for South Africa's Long-Term Mitigation Scenarios. → Provides details on methodology, drivers of emissions and key parameters. → In a scenario of Growth without Constraints, emissions would quadruple by 2050. → Analysis of resulting emission projection, not a prediction. → Compares projections from other national and international models.

  15. Mud-Bath Therapy in Addition to Usual Care in Bilateral Knee Osteoarthritis: An Economic Evaluation Alongside a Randomized Controlled Trial.

    Science.gov (United States)

    Ciani, Oriana; Pascarelli, Nicola Antonio; Giannitti, Chiara; Galeazzi, Mauro; Meregaglia, Michela; Fattore, Giovanni; Fioravanti, Antonella

    2017-07-01

    To perform a cost-effectiveness analysis of mud-bath therapy (MBT) in addition to usual treatment compared to usual treatment alone in patients with bilateral knee osteoarthritis (OA). An economic evaluation alongside a randomized controlled trial was conducted. Patients were randomly assigned to receive either a 2-week cycle of MBT in addition to their usual treatment or to continue routine care alone. The EuroQol 5-domain questionnaire was administered at baseline, 2 weeks, and at 3, 6, 9, and 12 months. Direct health care resource consumption data up until 12 months were derived from a daily diary given to patients and returned at prescheduled followup visits. A total of 103 patients were included (n = 53 for MBT patients; n = 50 for controls). Overall, patients in the MBT group accrued mean ± SD 0.835 ± 0.10 quality-adjusted life years (QALYs) compared to 0.753 ± 0.11 in the control group (P < 0.001). Average direct costs per patient (€303 versus €975; P < 0.001) were higher in the control group, primarily because of hospitalization for total knee replacement and use of intraarticular hyaluronic acid. Bootstrapping replications of costs and QALY sample distributions consistently indicated that the MBT therapy combined with standard therapy represents a dominant strategy as compared with standard therapy alone. The probability of MBT being cost-effective at standard cost-effectiveness thresholds (e.g., €20,000/QALY) is 100%. The results of this cost-effectiveness analysis support the use of MBT as midterm complementary therapy in the management of knee OA. © 2016, American College of Rheumatology.

  16. Efficacy of a minimal home-based psychoeducative intervention versus usual care for managing anxiety and dyspnoea in patients with severe chronic obstructive pulmonary disease

    DEFF Research Database (Denmark)

    Bove, Dorthe Gaby; Overgaard, Dorthe; Lomborg, Kirsten

    2015-01-01

    investigates the efficacy of a minimal home-based psychoeducative intervention versus usual care for patients with severe chronic obstructive pulmonary disease. METHODS AND ANALYSIS: The trial is a randomised controlled trial with a 4-week and 3-month follow-up. 66 patients with severe chronic obstructive...... pulmonary disease and associated anxiety will be randomised 1:1 to either an intervention or control group. The intervention consists of a single psychoeducative session in the patient's home in combination with a telephone booster session. The intervention is based on a manual, with a theoretical...

  17. Day Hospital Mentalization-Based Treatment (MBT-DH) versus treatment as usual in the treatment of severe borderline personality disorder: protocol of a randomized controlled trial

    Science.gov (United States)

    2014-01-01

    Background Severe borderline personality disorder is associated with a very high psychosocial and economic burden. Current treatment guidelines suggest that several manualized treatments, including day hospital Mentalization-Based Treatment (MBT-DH), are effective in these patients. However, only two randomized controlled trials have compared manualized MBT-DH with treatment as usual. Given the relative paucity of data supporting the efficacy and cost-effectiveness of MBT-DH, the possible influence of researcher allegiance in one of the trials, and potential problems with the generalization of findings to mental health systems in other countries, this multi-site randomized trial aims to investigate the efficacy and cost-effectiveness of manualized MBT-DH compared to manualized specialist treatment as usual in The Netherlands. Methods/design The trial is being conducted at two sites in The Netherlands. Patients with a DSM-IV-TR diagnosis of borderline personality disorder and a score of ≥ 20 on the Borderline Personality Disorder Severity Index were randomly allocated to MBT-DH or treatment as usual. The MBT-DH program consists of a maximum of 18 months’ intensive treatment, followed by a maximum of 18 months of maintenance therapy. Specialist treatment as usual is provided by the City Crisis Service in Amsterdam, a service that specializes in treating patients with personality disorders, offering manualized, non-MBT interventions including family interventions, Linehan training, social skills training, and pharmacotherapy, without a maximum time limit. Patients are assessed at baseline and subsequently every 6 months up to 36 months after the start of treatment. The primary outcome measure is the frequency and severity of manifestations of borderline personality disorder as assessed by the Borderline Personality Disorder Severity Index. Secondary outcome measures include parasuicidal behaviour, symptomatic distress, social and interpersonal functioning

  18. Efficacy of an adjunctive brief psychodynamic psychotherapy to usual inpatient treatment of depression: rationale and design of a randomized controlled trial

    Science.gov (United States)

    2012-01-01

    Background A few recent studies have found indications of the effectiveness of inpatient psychotherapy for depression, usually of an extended duration. However, there is a lack of controlled studies in this area and to date no study of adequate quality on brief psychodynamic psychotherapy for depression during short inpatient stay exists. The present article describes the protocol of a study that will examine the relative efficacy, the cost-effectiveness and the cost-utility of adding an Inpatient Brief Psychodynamic Psychotherapy to pharmacotherapy and treatment-as-usual for inpatients with unipolar depression. Methods/Design The study is a one-month randomized controlled trial with a two parallel group design and a 12-month naturalistic follow-up. A sample of 130 consecutive adult inpatients with unipolar depression and Montgomery-Asberg Depression Rating Scale score over 18 will be recruited. The study is carried out in the university hospital section for mood disorders in Lausanne, Switzerland. Patients are assessed upon admission, and at 1-, 3- and 12- month follow-ups. Inpatient therapy is a manualized brief intervention, combining the virtues of inpatient setting and of time-limited dynamic therapies (focal orientation, fixed duration, resource-oriented interventions). Treatment-as-usual represents the best level of practice for a minimal treatment condition usually proposed to inpatients. Final analyses will follow an intention–to-treat strategy. Depressive symptomatology is the primary outcome and secondary outcome includes measures of psychiatric symptomatology, psychosocial role functioning, and psychodynamic-emotional functioning. The mediating role of the therapeutic alliance is also examined. Allocation to treatment groups uses a stratified block randomization method with permuted block. To guarantee allocation concealment, randomization is done by an independent researcher. Discussion Despite the large number of studies on treatment of depression

  19. Effect of guided self-determination youth intervention integrated into outpatient visits versus treatment as usual on glycemic control and life skills

    DEFF Research Database (Denmark)

    Husted, Gitte R; Thorsteinsson, Birger; Esbensen, Bente Appel

    2014-01-01

    the amotivation for diabetes self-management after adjusting for the baseline value (P = 0.001). Compared with the control group, the trial completion was prolonged in the GSD-Y group (P ... of the adolescents' visits (P = 0.05) compared with control parents. CONCLUSIONS: Compared with treatment-as-usual, GSD-Y did not improve HbA1c levels, but it did decrease adolescents' amotivation for diabetes self-management.Trial registration: ISRCTN 54243636, registered on 10 January 2010. Life skills...

  20. Day Hospital Mentalization-Based Treatment (MBT-DH) versus treatment as usual in the treatment of severe borderline personality disorder: protocol of a randomized controlled trial.

    Science.gov (United States)

    Laurenssen, Elisabeth M P; Westra, Dieuwertje; Kikkert, Martijn J; Noom, Marc J; Eeren, Hester V; van Broekhuyzen, Anna J; Peen, Jaap; Luyten, Patrick; Busschbach, Jan J V; Dekker, Jack J M

    2014-05-22

    Severe borderline personality disorder is associated with a very high psychosocial and economic burden. Current treatment guidelines suggest that several manualized treatments, including day hospital Mentalization-Based Treatment (MBT-DH), are effective in these patients. However, only two randomized controlled trials have compared manualized MBT-DH with treatment as usual. Given the relative paucity of data supporting the efficacy and cost-effectiveness of MBT-DH, the possible influence of researcher allegiance in one of the trials, and potential problems with the generalization of findings to mental health systems in other countries, this multi-site randomized trial aims to investigate the efficacy and cost-effectiveness of manualized MBT-DH compared to manualized specialist treatment as usual in The Netherlands. The trial is being conducted at two sites in The Netherlands. Patients with a DSM-IV-TR diagnosis of borderline personality disorder and a score of ≥ 20 on the Borderline Personality Disorder Severity Index were randomly allocated to MBT-DH or treatment as usual. The MBT-DH program consists of a maximum of 18 months' intensive treatment, followed by a maximum of 18 months of maintenance therapy. Specialist treatment as usual is provided by the City Crisis Service in Amsterdam, a service that specializes in treating patients with personality disorders, offering manualized, non-MBT interventions including family interventions, Linehan training, social skills training, and pharmacotherapy, without a maximum time limit. Patients are assessed at baseline and subsequently every 6 months up to 36 months after the start of treatment. The primary outcome measure is the frequency and severity of manifestations of borderline personality disorder as assessed by the Borderline Personality Disorder Severity Index. Secondary outcome measures include parasuicidal behaviour, symptomatic distress, social and interpersonal functioning, personality functioning

  1. Effects of using the simplified airway risk index vs usual airway assessment on unanticipated difficult tracheal intubation - a cluster randomized trial with 64,273 participants

    DEFF Research Database (Denmark)

    Nørskov, A K; Wetterslev, J; Rosenstock, C V

    2016-01-01

    departments vs 1.00% (302) in Non-SARI departments. Adjusted OR was 1.26 (0.68-2.34). CONCLUSIONS: Using the SARI compared with usual airway assessment we detected no statistical significant changes in unanticipated difficult- or easy intubations. CLINICAL TRIAL REGISTRATION: NCT01718561.......BACKGROUND: Unanticipated difficult intubation remains a challenge in anaesthesia. The Simplified Airway Risk Index (SARI) is a multivariable risk model consisting of seven independent risk factors for difficult intubation. Our aim was to compare preoperative airway assessment based on the SARI...

  2. An innovative brioche enriched in protein and energy improves the nutritional status of malnourished nursing home residents compared to oral nutritional supplement and usual breakfast: FARINE+ project.

    Science.gov (United States)

    Van Wymelbeke, Virginie; Brondel, Laurent; Bon, Francis; Martin-Pfitzenmeyer, Isabelle; Manckoundia, Patrick

    2016-10-01

    To compare the effects of a 12-week nutritional intervention, in which an innovative protein-and-energy-enriched brioche, an oral nutritional supplement or a usual breakfast were eaten, on food intake and nutritional status in nursing home residents. Three-armed, multicentre, controlled trial. Eight nursing homes in Burgundy, France. Sixty-eight malnourished participants aged between 70 and 99 years old. Participants were randomly assigned to one of three groups according to the breakfast provided: brioche group, one portion of 65 g brioche enriched in protein and energy (12.8 g and 180 kcal) added to usual breakfast; supplement group, 200-ml of a ready-to-use, energy-dense liquid (14 g protein and 200 kcal) added to usual breakfast or control group, a usual breakfast only. Total energy intakes were assessed for three days at different periods of the study (day 0, day 30 and day 90); blood parameters, nutritional status (mini nutritional assessment, weight) and functional capacities (grip strength and activity level) were measured at the beginning and at the end of the nutritional intervention study (day 0 and day 90). The participants of the brioche group had higher total energy intakes at day 30 (p value 0.004) and at day 90 (p value 0.018) compared with the supplement group and the control group. At the end of the interventional study, 72% of the participants in the brioche group had reached the recommended minimum level of protein of 0.8 g/kg/day, compared with 53% in the supplement group and 36% in the control group (p value 0.036). In addition, between day 0 and day 90 in the brioche group, blood levels of vitamins B 9 , B 2 , D (all p value <0.001), B 6 (p value 0.026) and B 12 (p value 0.036) had increased and plasma homocysteine had decreased (p value 0.024). The protein-and-energy-enriched brioche effectively increased energy and protein intakes and improved the nutritional status of elderly people living in nursing homes. It could be a good

  3. Imagery rehearsal therapy in addition to treatment as usual for patients with diverse psychiatric diagnoses suffering from nightmares: a randomized controlled trial.

    Science.gov (United States)

    van Schagen, Annette M; Lancee, Jaap; de Groot, Izaäk W; Spoormaker, Victor I; van den Bout, Jan

    2015-09-01

    Nightmares are associated with psychopathology and daily distress. They are highly prevalent in a psychiatric population (30%). Currently, imagery rehearsal therapy (IRT) is the treatment of choice for nightmares. With IRT, the script of the nightmare is changed into a new dream, which is imagined during the day. However, the effects of IRT in a psychiatric population remain unknown. The aim of this study was to determine the effectiveness of IRT in a heterogeneous psychiatric population. Between January 2006 and July 2010, 90 patients with psychiatric disorders (DSM-IV-TR) were randomized to IRT or treatment-as-usual conditions. IRT consisted of 6 individual sessions added to the treatment as usual. Nightmare frequency was assessed using daily nightmare logs and the Nightmare Frequency Questionnaire. Nightmare distress was assessed using the Nightmare Distress Questionnaire and the Nightmare Effects Survey. General psychiatric symptoms were assessed using the Symptom Checklist-90 and a PTSD symptom questionnaire. Assessments were administered at the start of the trial, after the IRT and at follow-up 3 months later. IRT showed a moderate effect (Cohen d = 0.5-0.7, P effects were largely sustained at the 3-month follow-up (Cohen d = 0.4-0.6, P effective treatment for nightmares among patients with comorbid psychiatric disorders and can be employed in addition to the on-going treatment. ClinicalTrials.gov identifier: NCT00291031. © Copyright 2015 Physicians Postgraduate Press, Inc.

  4. Sharp Lines Due to Cr3+ and Mn2+ Impurities in Insulators: Going Beyond the Usual Tanabe−Sugano Approach

    DEFF Research Database (Denmark)

    García Lastra, Juan Maria; García-Fernández, P.; Barriuso, M. T.

    2014-01-01

    energies of MF6 complexes through the ten Coulomb and exchange integrals consistent with the cubic symmetry and not considered in the usual Tanabe-Sugano approach. It is shown that E((6)A1 → (4)A1) depends on exchange integrals K(3z(2) - r(2), xy) and K(x(2) - y(2), xy), while E((2)E → (4)A2) depends on K......This work is aimed at understanding the different behavior of optical sharp lines (corresponding to 10Dq-independent transitions) of Mn(2+) and Cr(3+) in normal and inverted perovskites that cannot be explained within the usual Tanabe-Sugano approach. In particular, we want to clarify why...... on passing from KMgF3:M to LiBaF3:M (M = Mn(2+), Cr(3+)) the energy, E((6)A1 → (4)A1), for Mn(2+) decreases by Δ = 1100 cm(-1), while Δ difference in these model systems is clarified by writing the transition...

  5. The third Symptom Management Research Trial in Oncology (SMaRT Oncology-3: a randomised trial to determine the efficacy of adding a complex intervention for major depressive disorder (Depression Care for People with Lung Cancer to usual care, compared to usual care alone in patients with lung cancer

    Directory of Open Access Journals (Sweden)

    Sharpe Michael

    2009-09-01

    Full Text Available Abstract Background Depression Care for People with Lung Cancer is a complex intervention delivered by specially trained cancer nurses, under the supervision of a psychiatrist. It is given as a supplement to the usual care for depression, which patients receive from their general practitioner and cancer service. The third Symptom Management Research Trial in Oncology (SMaRT Oncology-3 Trial will test its efficacy when compared to usual care alone. Design A two arm parallel group multi-centre randomised controlled trial. 200 patients will be recruited through established systematic Symptom Monitoring Services, which screen patients for depression. Patients will have: a diagnosis of lung cancer; an estimated life expectancy of three months or more and a diagnosis of Major Depressive Disorder. Patients will be randomised to usual care or usual care plus Depression Care for People with Lung Cancer. Randomisation will be carried out by telephoning a secure computerised central randomisation system or by using a secure web interface. The primary outcome measure is average depression severity. This will be assessed using scores on the 20-item Symptom Hopkins Checklist (SCL-20D, collected every four weeks over 32 weeks. Secondary outcomes include severity of anxiety, pain and fatigue; self-rated improvement of depression; quality of life and satisfaction with depression care. Trial Registration Current controlled trials ISRCTN75905964

  6. Outcome predictors in autism spectrum disorders preschoolers undergoing treatment as usual: insights from an observational study using artificial neural networks

    Directory of Open Access Journals (Sweden)

    Narzisi A

    2015-06-01

    Full Text Available Antonio Narzisi,1 Filippo Muratori,1,2 Massimo Buscema,3,4 Sara Calderoni,1 Enzo Grossi3,5 1Department of Developmental Neuroscience, IRCCS Stella Maris Foundation, 2Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 3Semeion Research Centre of Sciences of Communication, Rome, Italy; 4Department of Mathematical and Statistical Sciences, University of Colorado Denver, Denver, CO, USA; 5Autism Research Unit, Villa Santa Maria Institute, Tavernerio, Italy Background: Treatment as usual (TAU for autism spectrum disorders (ASDs includes eclectic treatments usually available in the community and school inclusion with an individual support teacher. Artificial neural networks (ANNs have never been used to study the effects of treatment in ASDs. The Auto Contractive Map (Auto-CM is a kind of ANN able to discover trends and associations among variables creating a semantic connectivity map. The matrix of connections, visualized through a minimum spanning tree filter, takes into account nonlinear associations among variables and captures connection schemes among clusters. Our aim is to use Auto-CM to recognize variables to discriminate between responders versus no responders at TAU.Methods: A total of 56 preschoolers with ASDs were recruited at different sites in Italy. They were evaluated at T0 and after 6 months of treatment (T1. The children were referred to community providers for usual treatments. Results: At T1, the severity of autism measured through the Autism Diagnostic Observation Schedule decreased in 62% of involved children (Response, whereas it was the same or worse in 37% of the children (No Response. The application of the Semeion ANNs overcomes the 85% of global accuracy (Sine Net almost reaching 90%. Consequently, some of the tested algorithms were able to find a good correlation between some variables and TAU outcome. The semantic connectivity map obtained with the application of the Auto-CM system showed

  7. Patient directed self management of pain (PaDSMaP compared to treatment as usual following total knee replacement: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Donell Simon

    2012-11-01

    Full Text Available Abstract Background In 2009, 665 patients underwent total knee replacements (TKRs at the Norfolk and Norwich University Hospitals NHS Foundation Trust (NNUH, representing nearly 1% of the national total. Pain control following the operation can be poor, and this can cause poor mobilization and potential long-term adverse events. Although high levels of pain are not associated with patient dissatisfaction, brief periods of pain may lead to neuronal remodeling and sensitization. Patient controlled oral analgesia (PCOA may improve pain relief; however, the evidence to date has been inconclusive. Patient directed self management of pain (PaDSMaP is a single center randomized controlled trial, which aims to establish if patient self-medication improves, or is equivalent to, treatment as usual and to create an educational package to allow implementation elsewhere. Methods/design Patients eligible for a TKR will be recruited and randomized in the outpatient clinic. All patients will undergo their operations according to normal clinical practice but will be randomized into two groups. Once oral medication has commenced, one group will have pain relief administered by nursing staff in the usual way (treatment as usual; TAU, whilst the second group will self manage their pain medication (patient directed self management of pain; PaDSMaP. Those recruited for self-medication will undergo a training program to teach the use of oral analgesics according to the World Health Organization (WHO pain cascade and how to complete the study documentation. The primary endpoint of the trial is the visual analogue scale (VAS pain score at 3 days or discharge, whichever is sooner. The follow-up time is 6 weeks with a planned trial period of 3 years. The secondary objectives are satisfaction with the management of patient pain post-operatively whilst an inpatient after primary TKR; overall pain levels and pain on mobilization; satisfaction with pain management information

  8. Early motion and directed exercise (EMADE) versus usual care post ankle fracture fixation: study protocol for a pragmatic randomised controlled trial.

    Science.gov (United States)

    Matthews, Paul A; Scammell, Brigitte E; Ali, Arfan; Coughlin, Timothy; Nightingale, Jessica; Khan, Tanvir; Ollivere, Ben J

    2018-05-31

    Following surgical fixation of ankle fractures, the traditional management has included immobilisation for 6 weeks in a below-knee cast. However, this can lead to disuse atrophy of the affected leg and joint stiffness. While early rehabilitation from 2 weeks post surgery is viewed as safe, controversy remains regarding its benefits. We will compare the effectiveness of early motion and directed exercise (EMADE) ankle rehabilitation, against usual care, i.e. 6 weeks' immobilisation in a below-knee cast. We have designed a pragmatic randomised controlled trial (p-RCT) to compare the EMADE intervention against usual care. We will recruit 144 independently living adult participants, absent of tissue-healing comorbidities, who have undergone surgical stabilisation of isolated Weber B ankle fractures. The EMADE intervention consists of a non-weight-bearing progressive home exercise programme, complemented with manual therapy and education. Usual care consists of immobilisation in a non-weight-bearing below-knee cast. The intervention period is between week 2 and week 6 post surgery. The primary outcome is the Olerud and Molander Ankle Score (OMAS) patient-reported outcome measure (PROM) at 12 weeks post surgery. Secondary PROMs include the EQ-5D-5 L questionnaire, return to work and return to driving, with objective outcomes including ankle range of motion. Analysis will be on a