WorldWideScience

Sample records for complex medium-sized chemicals

  1. Thermodynamic method for obtaining the solubilities of complex medium-sized chemicals in pure and mixed solvents

    DEFF Research Database (Denmark)

    Abildskov, Jens; O'Connell, J.P.

    2005-01-01

    This paper extends our previous simplified approach to using group contribution methods and limited data to determine differences in solubility of sparingly soluble complex chemicals as the solvent is changed. New applications include estimating temperature dependence and the effect of adding...... cosolvents forming strongly nonideal aqueous mixtures and including immiscibility. The method optimally selects a 'reference solvent' from limited data, which effectively eliminates the need for pure-solute properties and minimizes the impact of their uncertainties. The technique also decreases the number....... Though we present no new solution theory, the paper shows an especially efficient use of thermodynamic models for solvent and cosolvent selection for product formulations. Examples and discussion of applications are given. (c) 2004 Elsevier B.V. All rights reserved....

  2. An Intervention Study on the Implementation of Control Banding in Controlling Exposure to Hazardous Chemicals in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Jeroen Terwoert

    2016-09-01

    Conclusion: Active training and coaching helped the participating companies to improve their chemical risk management, and to avoid making mistakes when using and applying Stoffenmanager. The use of validated tools embedded in a community platform appears to support companies to organize and structure their chemical risk management in a business-wise manner, but much depends upon motivated occupational health and safety (OHS professionals, management support, and willingness to invest time and means.

  3. Chemical weapon functional exercise--Cincinnati: observations and lessons learned from a "typical medium-sized" city's response to simulated terrorism utilizing Weapons of Mass Destruction.

    Science.gov (United States)

    FitzGerald, Denis J; Sztajnkrycer, Matthew D; Crocco, Todd J

    2003-01-01

    In the wake of the September 11, 2001, attacks and the subsequent anthrax scare, there is growing concern about the United States' vulnerability to terrorist use of Weapons of Mass Destruction (WMD). As part of ongoing preparation for this terrible reality, many jurisdictions have been conducting simulated terrorist incidents to provide training for the public safety community, hospitals, and public health departments. As an example of this national effort to improve domestic preparedness for such events, a large scale, multi-jurisdictional chemical weapons drill was conducted in Cincinnati, Ohio, on May 20, 2000. This drill depicted the components of the early warning system for hospitals and public health departments, the prehospital medical response to terrorism. Over the course of the exercise, emergency medical services personnel decontaminated, triaged, treated, and transported eighty-five patients. Several important lessons were learned that day that have widespread applicability to health care delivery systems nationwide, especially in the areas of decontamination, triage, on-scene medical care, and victim transportation. As this training exercise helped Cincinnati to prepare for dealing with future large scale WMD incidents, such drills are invaluable preparation for all communities in a world increasingly at risk from terrorist attacks.

  4. HIRENASD Chimera medium-size grid

    Data.gov (United States)

    National Aeronautics and Space Administration — Chimera medium-size grid for HIRENASD. Two files, fort.501 for grid for wing, fuselage, and 'world' zones, fort.503 for collar zone. File format is plot3d,...

  5. to medium-sized water distribution systems

    African Journals Online (AJOL)

    Framework for optimizing chlorine dose in small- to medium-sized water distribution systems: A case of a residential neighbourhood in Lahore, Pakistan. ... The bulk decay coefficient (Kb) was determined in the laboratory, whereas the wall decay coefficient (Kw) was estimated by calibrating the simulation results with the ...

  6. AN INVESTIGATION INTO MEDIUM-SIZED MULTINATIONAL ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Daniele Schilirò

    2013-09-01

    Full Text Available The paper provides an investigation of medium-sized Italian industrial enterprises that have become multinational companies. It concetrates on the set of medium and medium-large enterprises who seem to grow more in foreign markets, either through exports or through foreign direct investment. The work also offers a descriptive empirical picture of the performance of medium-sized Italian multinationals, which is compared with the performance of large corporations. From this analysis, which is based on several data sources, it is possible to outline a profile regarding the medium-size italian multinational enterprises; the aim is to understand the complex strategy towards internationalization of these companies, where the dimension of production is important and, therefore, innovation has a key role. Also the commercial dimension is crucial, because it leads to point to the direct supervision of foreign markets and to look very carefully at the customers, offering them a wide range of services. Finally, the paper highlights some critical issues that the medium sized multinational enterprises have to face for competing: namely, the stagnant productivity, the high taxation, the insufficient institutional support for internationalization, the bureaucracy and its high costs, the lack of skilled human capital available in the labor market due to inadequate policy training.

  7. Efficiency optimized control of medium-size induction motor drives

    DEFF Research Database (Denmark)

    Abrahamsen, F.; Blaabjerg, Frede; Pedersen, John Kim

    2000-01-01

    The efficiency of a variable speed induction motor drive can be optimized by adaption of the motor flux level to the load torque. In small drives (small converter losses, but for medium-size drives (10-1000 kW) the losses can...... not be disregarded without further analysis. The importance of the converter losses on efficiency optimization in medium-size drives is analyzed in this paper. Based on the experiments with a 90 kW drive it is found that it is not critical if the converter losses are neglected in the control, except...... that the robustness towards load disturbances may unnecessarily be reduced. Both displacement power factor and model-based efficiency optimizing control methods perform well in medium-size drives. The last strategy is also tested on a 22 kW drive with good results....

  8. Holonic Business Process Modeling in Small to Medium Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Nur Budi Mulyono

    2012-01-01

    Full Text Available Holonic modeling analysis which is the application of system thinking in design, manage, and improvement, is used in a novel context for business process modeling. An approach and techniques of holon and holarchies is presented specifically for small and medium sized enterprise process modeling development. The fitness of the approach is compared with well known reductionist or task breakdown approach. The strength and weaknesses of the holonic modeling is discussed with illustrating case example in term of its suitability for an Indonesia’s small and medium sized industry. The novel ideas in this paper have great impact on the way analyst should perceive business process. Future research is applying the approach in supply chain context.Key words: Business process, holonic modeling, operations management, small to medium sized enterprise

  9. Sales strategy in small and medium-sized food companies

    DEFF Research Database (Denmark)

    Nielsen, Renate; Stacey, Julia; Andersen, Lone Merete Schreiber

    2002-01-01

    All managing teams know that they have to deal with the company's strategy in handling the market. But how do they do it and on the basis of which beleifs and interpretations? A nearly completed PhD project has examined the way in which three small and medium-sized food companies define their mar......All managing teams know that they have to deal with the company's strategy in handling the market. But how do they do it and on the basis of which beleifs and interpretations? A nearly completed PhD project has examined the way in which three small and medium-sized food companies define...

  10. Unions in small and medium-sized enterprises

    DEFF Research Database (Denmark)

    Holten, Ann-Louise; Crouch, Colin

    2014-01-01

    Trade unions are commonly weak in small- and medium-sized enterprises, which constitute a majority of European firms and are often family-owned. We investigate the influence of family ownership on employee membership, perceptions and experience with unions in Danish and Italian firms in the textile...

  11. Legal and Administrative Constraints to Small and Medium Sized ...

    African Journals Online (AJOL)

    101 SME (Small and Medium-sized Enterprise) operators were interviewed in a sample survey in Douala, Cameroon, to elicit the legal and administrative constraints to the creation and functioning of SMEs in Cameroon. The fulfilment of business entry requirements entails transactions costs which are by far more than the ...

  12. Export Marketing Involvement of African Small and Medium Size ...

    African Journals Online (AJOL)

    The extent to which small and medium size enterprises (SME's) are engaged in marketing their products in foreign markets is an important factor that can increase their performance in those markets. This study examined the Export marketing involvement of SMEs from the Least Developed Countries using the case study of ...

  13. The structural analysis of small and medium size furniture ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-12-17

    Dec 17, 2008 ... A sector based questionnaire study related to analyzing the structures of small and medium size furniture enterprises in Turkish furniture .... ing information and evaluation of the data at sector base without focusing on either ... duction, marketing, financial, organization and enterprise management and also ...

  14. White stumpnose Rhabdosargus globiceps is a medium- sized ...

    African Journals Online (AJOL)

    White stumpnose Rhabdosargus globiceps is a medium- sized (attaining 3 kg total weight), endemic, temperate sparid, and is recorded from southern Angola to the. Kei River on the east coast of South Africa (Whitfield. 1998). It is an important recreational and commercial linefish off the west and south coasts of South Africa.

  15. Development of software tool support for enterprise architecture in small and medium-sized enterprises

    OpenAIRE

    Dumeez, Joost; Bernaert, Maxime; Poels, Geert

    2013-01-01

    Part 4: Enterprise Modelling Approaches and Tools for Agility and Flexibility; International audience; Enterprise architecture (EA) is used to improve the alignment of different facets of a company. The recognition for the need of EA in small and medium-sized enterprises (SMEs) has recently risen as a means to manage complexity and change [1]. Due to the specific problems and characteristics of SMEs, a different approach is necessary. CHOOSE was therefore developed as an EA approach focused o...

  16. Some Essentials Charakteristicks of Small and Medium Sized Enterprises

    OpenAIRE

    Drahoš Vaněček; Pavel Fára

    2012-01-01

    Small and medium sized enterprises were investigated by means of university students who helped managers to fulfill 185 questionnaires. Questionnaires were sorted according to the size of firms into 4 groups [1-9, 10-24, 25-49, 50-249 employees] and according to the branches [Industrial production, Building firms, Woodwork, Food processing firms, Retail business, Services including transportation]. The main indicators concern the size of firms, number of employees, productivity, legal form, n...

  17. Fracture mechanics characterisation of medium-size adhesive joint specimens

    DEFF Research Database (Denmark)

    Sørensen, Bent F.; Jacobsen, T.K.

    2004-01-01

    Medium-size specimens (adhesive layer were tested in four point bending to determine their load carrying capacity. Specimens having different thickness were tested. Except for onespecimen, the cracking occurred as cracking...... along the adhesive layer; initially cracking occurred along the adhesive/laminate interface, but after some crack extension the cracking took place inside the laminate (for one specimen the later part of thecracking occurred unstably along the adhesive/ laminate interface). Crack bridging by fibres...

  18. Efficiency optimized control of medium-size induction motor drives

    DEFF Research Database (Denmark)

    Abrahamsen, F.; Blaabjerg, Frede; Pedersen, John Kim

    2000-01-01

    The efficiency of a variable speed induction motor drive can be optimized by adaption of the motor flux level to the load torque. In small drives (<10 kW) this can be done without considering the relatively small converter losses, but for medium-size drives (10-1000 kW) the losses can not be disr......The efficiency of a variable speed induction motor drive can be optimized by adaption of the motor flux level to the load torque. In small drives (

  19. MANUFACTURING ORIENTED DESIGN IN SMALL AND MEDIUM SIZE FACTORIES

    Directory of Open Access Journals (Sweden)

    J. Peters

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Special circumstances and considerations for the implementation of Computer Integrated Manufacturing principles in small and medium size factories are identified and discussed. An approach for esthablishing such programs is suggested and illustrated with a number of examples.

    AFRIKAANSE OPSOMMING: Spesiale omstandighede en oorwegings vir die implementering van Rekenaargeintegreerde Vervaardigingsbeginsels in klein en mediumgrootte fabrieke word geidentifiseer en bespreek. 'n Benadering vir die daarstelling van sodanige programme word voorgestel en geillustreer met behulp van verskeie voorbeelde.

  20. Preliminary conceptual design of a medium sized tokamak (IST-1)

    Science.gov (United States)

    Bagerpour, M.; Alinejad, N.; Sobhanian, S.

    2015-08-01

    In this paper an attempt is made to estimate the main parameters of the Iranian superconducting tokamak as a medium sized tokamak. In the first stage, the production and confinement of ohmically heated plasma is considered. Considering the aim of the design and the kink stability limit, three main parameters are assumed to be known. Using the known theoretical, empirical scale laws and numerical solution of Grad-Shafranov equation for a D-shaped plasmas and also considering the correction terms due to triangularity of the torus cross section, other physical and geometrical parameters have been estimated. The magnetic flux surfaces, plasma pressure and toroidal current density profiles are found by solving of Grad-Shafranov equation as an eigenvalue problem using finite element method. The preliminary results are compared with some recent tokamaks now in operation in different research centers.

  1. Entrepreneurial Orientation vs. Innovativeness of Small and Medium Size Enterprises

    Directory of Open Access Journals (Sweden)

    Joanna Ejdys

    2016-01-01

    Full Text Available This study aims to examine the role of entrepreneurial orientation (entrepreneurship orientation in innovation level among Small and Medium Size Enterprises (SMEs. A questionnaire survey was conducted among 137 firms in the Podlaskie Region. Three hypotheses related to entrepreneurial orientation and innovativeness level were examined by Structural Equation Modeling (SEM. The relation between two constructs of entrepreneurial orientation and innovativeness, that is proactiveness and risk taking were analyzed. The research results show that proactiveness has a significant positive total effect on improving innovativeness. The findings suggest, in contrast to the strategic orientation literature, that risk taking deters enterprises from organizational innovation. The results confirmed the significantly higher impact of the risk taking as an intermediate variable on the innovation through the mediator of proactivity. This work examines the relations between entrepreneurial orientation and innovativeness, thus contributes to the strategic orientation literature.

  2. Significance assessment of small-medium sized reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kanno, Minoru [Japan Atomic Power Co., Research and Development Dept., Tokyo (Japan)

    2002-12-01

    Preliminary assessment for deployment of small-medium sized reactor (S and M reactor) as a future option has been conducted at the JAPCO (Japan Atomic Power Company) under the cooperation with the CRIERI (Central Research Institute of Electric Power Industry). Significance of the S and M reactor introduction is listed as follows; lower investment cost, possible siting near demand side, enlarged freedom of siting, shorter transmission line, good compatibility with slow increase of demand and plain explanation of safety using simpler system such as integral type vessel without piping, natural convection core cooling and passive safety system. The deployment of simpler plant system, modular shop fabrication, ship-shell structured building and longer operation period can assure economics comparable with that of a large sized reactor, coping with scale-demerit. Also the S and M reactor is preferable in size for the nuclear heat utilization such as hydrogen production. (T. Tanaka)

  3. Small and medium sized enterprises (SMEs and transfer pricing

    Directory of Open Access Journals (Sweden)

    Veronika Solilová

    2012-01-01

    Full Text Available Small and medium sized enterprises have very important position in the EU economy, mainly in the area of growth and employment. However, most of SMEs are active only in their home country and only a few of them participate in cross-border activities. Furthermore, their activities in the internal market are limited by great deal of obstacles, mainly in the form of different tax systems which generate excessive compliance costs of taxation and the existence of different SMEs definitions for various purposes in Member states. In addition, from the view of the international taxation issues, the most important obstacles can be considered a transfer pricing and cross-border loss compensations. In this area, SMEs are facing specific problems and have specific needs. The aim of the paper is to analyze and evaluate the specific transfer pricing issues of SMEs and propose recommendations for them.

  4. A Bayesian Approach to International Distributor Selection for Small and Medium-Sized Enterprises in the Software Industry

    Science.gov (United States)

    Lui, Joseph P.

    2013-01-01

    Identifying appropriate international distributors for small and medium-sized enterprises (SMEs) in the software industry for overseas markets can determine a firm's future endeavors in international expansion. SMEs lack the complex skills in market research and decision analysis to identify suitable partners to engage in global market entry.…

  5. Salary Management System for Small and Medium-sized Enterprises

    Science.gov (United States)

    Hao, Zhang; Guangli, Xu; Yuhuan, Zhang; Yilong, Lei

    Small and Medium-sized Enterprises (SMEs) in the process of wage entry, calculation, the total number are needed to be done manually in the past, the data volume is quite large, processing speed is low, and it is easy to make error, which is resulting in low efficiency. The main purpose of writing this paper is to present the basis of salary management system, establish a scientific database, the computer payroll system, using the computer instead of a lot of past manual work in order to reduce duplication of staff labor, it will improve working efficiency.This system combines the actual needs of SMEs, through in-depth study and practice of the C/S mode, PowerBuilder10.0 development tools, databases and SQL language, Completed a payroll system needs analysis, database design, application design and development work. Wages, departments, units and personnel database file are included in this system, and have data management, department management, personnel management and other functions, through the control and management of the database query, add, delete, modify, and other functions can be realized. This system is reasonable design, a more complete function, stable operation has been tested to meet the basic needs of the work.

  6. Medium-sized aperture camera for Earth observation

    Science.gov (United States)

    Kim, Eugene D.; Choi, Young-Wan; Kang, Myung-Seok; Kim, Ee-Eul; Yang, Ho-Soon; Rasheed, Ad. Aziz Ad.; Arshad, Ahmad Sabirin

    2017-11-01

    Satrec Initiative and ATSB have been developing a medium-sized aperture camera (MAC) for an earth observation payload on a small satellite. Developed as a push-broom type high-resolution camera, the camera has one panchromatic and four multispectral channels. The panchromatic channel has 2.5m, and multispectral channels have 5m of ground sampling distances at a nominal altitude of 685km. The 300mm-aperture Cassegrain telescope contains two aspheric mirrors and two spherical correction lenses. With a philosophy of building a simple and cost-effective camera, the mirrors incorporate no light-weighting, and the linear CCDs are mounted on a single PCB with no beam splitters. MAC is the main payload of RazakSAT to be launched in 2005. RazakSAT is a 180kg satellite including MAC, designed to provide high-resolution imagery of 20km swath width on a near equatorial orbit (NEqO). The mission objective is to demonstrate the capability of a high-resolution remote sensing satellite system on a near equatorial orbit. This paper describes the overview of the MAC and RarakSAT programmes, and presents the current development status of MAC focusing on key optical aspects of Qualification Model.

  7. Overview of the EUROfusion Medium Size Tokamak program

    Science.gov (United States)

    Martin, Piero; Beurskens, Marc; Coda, Stefano; Eich, Thomas; Meyer, Hendrik; the EUROfusion MST1 Team

    2015-11-01

    As a result of the new organization of the European fusion programme, now under the umbrella of the EUROfusion Consortium, the MST (Medium Size Tokamaks) task force is in charge of executing the European science programme in the ASDEX Upgrade, TCV and MAST-U tokamaks. This paper will present an overview of the main results obtained in the 2014 campaign-where only ASDEX upgrade was operating-and the preliminary achievements of the recently started 2015/16 campaign, where also TCV will contribute. The main subjects of the experimental campaigns are (i) the development of scenarios relevant for the ITER Q=10 goal, in an all metal wall device (ii) the understanding of ELM mitigation/suppression with pellets and resonant magnetic perturbations, and in particular the effect of density versus collisionality, (iii) the understanding and optimization of methods for disruption mitigation or avoidance and runaway electrons control and (iv) the exploration of ITER and DEMO relevant scenarios with high normalized separatrix power flux, Psep / R , (Psep is the power through the separatrix, R the major radius) and tolerable target heat loads. The overview of the future programs in MST will be given. http://www.euro-fusionscipub.org/mst1

  8. Climatic Effects of Medium-Sized Asteroid Impacts on Land

    Science.gov (United States)

    Bardeen, C.; Garcia, R. R.; Toon, O. B.; Otto-Bliesner, B. L.; Wolf, E. T.

    2015-12-01

    Using the Community Earth System Model (CESM), a three-dimensional coupled climate model with interactive chemistry, we have simulated the climate response to a medium-sized (1 km) asteroid impact on the land. An impact of this size would cause local fires and may also generate submicron dust particles. Dust aerosols are injected into the upper atmosphere where they persist for ~3 years. Soot aerosols from fires are injected into the troposphere and absorb solar radiation heating the air which helps loft the soot into the stratosphere where it persists for ~10 years. Initially, these aerosols cause a heating of over 240 K in the stratosphere and up to a 70% reduction in downwelling solar radiation at the surface. Global average surface temperature cools by as much as -8.5 K, ocean temperature cools by -4.5 K, precipitation is reduced by 50%, and the ozone column is reduced by 55%. The surface UV Index exceeds 20 in the tropics for several years. These changes represent a significant hazard to life on a global scale. These results extend the work of Pierazzo et al. (2010), also using CESM, which found a significant impact on stratospheric ozone, but little change in surface temperature or precipitation, from a 1 km asteroid impact in the ocean.

  9. Penetration of small and medium sized food companies on foreign markets

    Directory of Open Access Journals (Sweden)

    Ladislav Mura

    2010-01-01

    Full Text Available In the world the interconnection of national economies and internationalization of economic processes occur. In turbulent changing business environment only those companies that understand the current trends in global economy may survive, develop and prosper. Therefore, the issue of internationalization for most companies becomes to be more important and the process of in­ter­na­tio­na­li­za­tion is the way how to stand this increasingly competitive environment. In presented contribution, the attention is paid to issues of internationalization of Slovak food industry enterprises such as their way of business internationalization, percentage share of foreign - trading activities on overall business activity, company evaluation of business internationalization or barriers of foreign markets pe­ne­tra­tion that researched companies have to deal with. Small and medium-sized enterprises (SMEs are the engine of the Slovak economy, generator of development, innovation, growth and they employ more than 60% of employees. Almost all businesses operating in agri-food complex have character of small and medium enterprises. The results of carried research have shown that small and medium-sized companies are considered to be successful in operation on foreign markets in surrounding European countries.

  10. Use of sales and operations planning in small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Michał Adamczak

    2013-03-01

    Full Text Available Background: Increasing competitiveness in the market, customer expectations related to the shortening of the deadlines and the reduction of prices of products and services force companies to improve the efficiency of internal processes. The integration of planning process is one of possible ways to achieve this aim. The integration of planning processes by the use of SOP model (Sales and Operations Planning is a method to implement this idea. The study allowed to identify ways to implement the process of sales and operations planning in small and medium-sized enterprises. Material and methods: The study was conducted in companies from different industries. The research method was in-depth interviews conducted with managers of companies or persons occupying management positions in the organizational process of implementing sales and operations planning. Results: During the survey, 10 companies were asked about the use of sales and operations planning, its elements and organizational aspects of its development, by the company. Conclusions: The use of sales and operations plan is closely dependent on the size of the company and its localization in the supply chain. Small enterprises are not interested in the integration of the planning process due to the small scale of operations and the centralization of decision-making process. Medium-sized enterprises, due to the increased complexity of the processes of planning, see the benefits of their integration in the SOP model.

  11. Copper complexes as chemical nucleases

    Indian Academy of Sciences (India)

    Keywords. Copper(II) complexes; nuclease activity; catalytic properties; DNA binding. Abstract. Redox active mononuclear and binuclear copper(II) complexes have been prepared and structurally characterized. ... The cleavage activity of the bis-dpq complex is significantly higher than the bis-phen complex of copper(II).

  12. Management of small and medium size enterprises as a carrier of economic growth

    Directory of Open Access Journals (Sweden)

    Ožegović Lazar

    2012-01-01

    Full Text Available Numerous studies in the world of market economy show that the share of small and medium size enterprises is constantly increasing compared to large enterprises. This does not decrease the significance of large enterprises, but the dependence between them gets larger every day. National economies which manage to find the optimal combination between small, medium size and large enterprises are more successful than the others. Management of small and medium size enterprises (SMEs in conceptual terms is similar to the process of management of large enterprises. An organization must be managed in order to function and this rule applies to small and medium size enterprises.

  13. Determinants of Tax Compliance Behaviour of Small and Medium Size Businesses in Cameroon's Littoral and Central Provinces

    OpenAIRE

    AKİNBOADE, Oludele Akinloye

    2014-01-01

    The paper reports the results of a survey of 575 small and medium size businesses operating in the manufacturing and wholesale sectors, that seeks to examine tax compliance behaviour in Cameroon's Littoral and Central Provinces. The study suggests that high registration cost and time consuming processes promote non-compliance of SME operators. The perception of a complex tax system results in registration non-compliance. A tedious compliance process results in filing non-compliance of SME own...

  14. Determinants of Tax Compliance Behaviour of Small and Medium Size Businesses in Cameroon's Littoral and Central Provinces

    OpenAIRE

    AKİNBOADE, Oludele Akinloye

    2014-01-01

    The paper reports the results of a survey of 575 small and medium size businesses operating in the manufacturing and wholesale sectors, that seeks to examine tax compliance behaviour in Cameroon's Littoral and Central Provinces. The study suggests that high registration cost and time consuming processes promote non-compliance of SME operators. The perception of a complex tax system results in registration non-compliance. A tedious compliance process results in filing non-compliance of SM...

  15. Copper complexes as chemical nucleases

    Indian Academy of Sciences (India)

    Unknown

    intercalation more favourable between the π-system of the ligand and the DNA base pairs. The dpq and dppz complexes, however, drastically differ in their cleavage activities in presence of a reducing agent like ascorbic acid. The anomalous activity of 5 could be related to the enhancement of the stability of the cuprous ...

  16. Expedient total synthesis of small to medium-sized membrane proteins via Fmoc chemistry.

    Science.gov (United States)

    Zheng, Ji-Shen; Yu, Mu; Qi, Yun-Kun; Tang, Shan; Shen, Fei; Wang, Zhi-Peng; Xiao, Liang; Zhang, Longhua; Tian, Chang-Lin; Liu, Lei

    2014-03-05

    Total chemical synthesis provides a unique approach for the access to uncontaminated, monodisperse, and more importantly, post-translationally modified membrane proteins. In the present study we report a practical procedure for expedient and cost-effective synthesis of small to medium-sized membrane proteins in multimilligram scale through the use of automated Fmoc chemistry. The key finding of our study is that after the attachment of a removable arginine-tagged backbone modification group, the membrane protein segments behave almost the same as ordinary water-soluble peptides in terms of Fmoc solid-phase synthesis, ligation, purification, and mass spectrometry characterization. The efficiency and practicality of the new method is demonstrated by the successful preparation of Ser64-phosphorylated M2 proton channel from influenza A virus and the membrane-embedded domain of an inward rectifier K(+) channel protein Kir5.1. Functional characterizations of these chemically synthesized membrane proteins indicate that they provide useful and otherwise-difficult-to-access materials for biochemistry and biophysics studies.

  17. Evaluation research of small and medium-sized enterprise informatization on big data

    Science.gov (United States)

    Yang, Na

    2017-09-01

    Under the background of big data, key construction of small and medium-sized enterprise informationization level was needed, but information construction cost was large, while information cost of inputs can bring benefit to small and medium-sized enterprises. This paper established small and medium-sized enterprise informatization evaluation system from hardware and software security level, information organization level, information technology application and the profit level, and information ability level. The rough set theory was used to brief indexes, and then carry out evaluation by support vector machine (SVM) model. At last, examples were used to verify the theory in order to prove the effectiveness of the method.

  18. Tax compliance costs for small and medium sized enterprises: the case of the UK

    National Research Council Canada - National Science Library

    Ann Hansford; John Hasseldine

    2012-01-01

      This paper presents a section of the findings from the UK arm of an international research project that is evaluating and comparing tax compliance costs affecting small and medium sized enterprises (SME...

  19. Local governments and climate change: sustainable energy planning and implementation in small and medium sized communities

    National Research Council Canada - National Science Library

    Van Staden, Maryke; Musco, Francesco

    2010-01-01

    The focus of 'Local governments and climate change' is on how small and medium-sized communities in Europe are effectively responding to climate change, with a particular focus on different approaches...

  20. Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand.

    Directory of Open Access Journals (Sweden)

    Samuel DeLuca

    Full Text Available RosettaLigand has been successfully used to predict binding poses in protein-small molecule complexes. However, the RosettaLigand docking protocol is comparatively slow in identifying an initial starting pose for the small molecule (ligand making it unfeasible for use in virtual High Throughput Screening (vHTS. To overcome this limitation, we developed a new sampling approach for placing the ligand in the protein binding site during the initial 'low-resolution' docking step. It combines the translational and rotational adjustments to the ligand pose in a single transformation step. The new algorithm is both more accurate and more time-efficient. The docking success rate is improved by 10-15% in a benchmark set of 43 protein/ligand complexes, reducing the number of models that typically need to be generated from 1000 to 150. The average time to generate a model is reduced from 50 seconds to 10 seconds. As a result we observe an effective 30-fold speed increase, making RosettaLigand appropriate for docking medium sized ligand libraries. We demonstrate that this improved initial placement of the ligand is critical for successful prediction of an accurate binding position in the 'high-resolution' full atom refinement step.

  1. AN ILLUSTRATION: APPLICABILITY OF ACTIVITY BASED COSTING ON SMALL-TO MEDIUM SIZED FIRMS

    OpenAIRE

    Tenker, Nejat; Arifoğlu, Mürühan

    2014-01-01

    The purpose of this study is to identify the applicability of “Activity Based Costing” in a small-and medium sized companies. Two major cost allocation approaches (i.e., Traditional and Activity Based Costing) were analyzed to indicate results of ABC application has significant differences from the existing cost systems of small-and medium sized companies. A sample of Cypriot Mattress factory: Luksor is selected. Under the light of Cooper hierarchy model, existing system of the factory is ana...

  2. Study on information strategic planning for large and medium-sized enterprise

    Science.gov (United States)

    Chen, Min; Tan, Shaosheng

    2011-10-01

    Enterprise Information is an inevitable trend in management change for large and medium-sized enterprises and also the basic conditions for company's future business, which has become an indispensable part of the overall strategy. Based on analyzing current situation in enterprise information especially that in China, its information strategy-based factors and its existing outstanding issues in China, the paper tries to explore information strategic planning for large and medium-sized enterprises.

  3. Transformational and transactional leadership: does it work in small to medium-sized enterprises?

    OpenAIRE

    Mesu, J.K.

    2013-01-01

    Using a sample of 755 employees who rated 121 supervisors within 50 Dutch small and medium-sized enterprises (SMEs), this dissertation intends to fill in some of the existing gaps in the literature. Firstly, by investigating whether the impact of transformational and transactional leadership extends from large to small and medium-sized companies. Secondly, by studying potential mediating and moderating effects to obtain a better understanding of the mechanisms by which transformational and tr...

  4. The business environment and phases of development of small and medium-sized enterprises

    OpenAIRE

    Wach, Krzysztof

    2006-01-01

    The subject literature distinguishes several factors that determine the establishment, survival , operations and development of micro, small, and medium-sized enterprises in particular regions. In this article, the author presents a classification of these factors in terms of whether they are barriers or stimulators. On this basis, the author explains the influence of regional environment (meso-environment) factors on the development of small and medium-sized enterprises in various phases of ...

  5. Human resources management within the process management in small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Marie Duspivová

    2013-01-01

    Full Text Available Sector of small and medium-sized enterprises is regarded as the backbone of the economy and a driving force of innovation, employment and social integration. Development of the sector of small and medium-sized enterprises in the Czech Republic has a substantial impact on economic and social development of the country and its various regions. This article deals with the human resources management in small and medium-sized enterprises, because it is more than obvious recently that the prosperity of the organization is depended on human resources and management of them can determine not only whether the organizations succeed, but whether it will be able to survive in turbulent conditions in the present world. The main aim of this paper is to analytical describe the monitoring the process of human resources management in selected categories of enterprises by business activity and number of employees including statistical analysis of causal effects. Further to analytical describe the evaluation the process of human resources management and indicators of this process, which are monitored by small and medium-sized enterprises. To achieve this aim were used selected primary data collected in the project GAJU 068/2010/S titled “Process management and its possible implementation in small and medium-sized enterprises”.

  6. Vacuum Ultraviolet Photoionization of Complex Chemical Systems.

    Science.gov (United States)

    Kostko, Oleg; Bandyopadhyay, Biswajit; Ahmed, Musahid

    2016-05-27

    Tunable vacuum ultraviolet (VUV) radiation coupled to mass spectrometry is applied to the study of complex chemical systems. The identification of novel reactive intermediates and radicals is revealed in flame, pulsed photolysis, and pyrolysis reactors, leading to the elucidation of spectroscopy, reaction mechanisms, and kinetics. Mass-resolved threshold photoelectron photoion coincidence measurements provide unprecedented access to vibrationally resolved spectra of free radicals present in high-temperature reactors. Photoionization measurements in water clusters, nucleic acid base dimers, and their complexes with water provide signatures of proton transfer in hydrogen-bonded and π-stacked systems. Experimental and theoretical methods to track ion-molecule reactions and fragmentation pathways in intermolecular and intramolecular hydrogen-bonded systems in sugars and alcohols are described. Photoionization of laser-ablated molecules, clusters, and their reaction products inform thermodynamics and spectroscopy that are relevant to astrochemistry and catalysis. New directions in coupling VUV radiation to interrogate complex chemical systems are discussed.

  7. The role of independent intermediaries. The case of small and medium-sized exporters

    DEFF Research Database (Denmark)

    Madsen, Tage Koed; Moen, Øystein; Hammervold, Randi

    2012-01-01

    The article examines how small and medium-sized exporters collaborate with intermediaries in foreign markets by studying the level of control, i.e. the delegation of decisions rights and task solution. It goes one step further than previous research, since it examines degrees of control and parti......The article examines how small and medium-sized exporters collaborate with intermediaries in foreign markets by studying the level of control, i.e. the delegation of decisions rights and task solution. It goes one step further than previous research, since it examines degrees of control...... and participation rather than just discrete types of intermediary modes (agents, importers, dealers, etc.). Associations with performance as well as the role of product and distributor characteristics are analyzed. Empirical data based on a sample of product-market ventures in 227 small and medium-sized Norwegian...

  8. A survey of the use of operational research in decisions made by micro, small and medium-sized enterprises in Macedonia

    Directory of Open Access Journals (Sweden)

    Violeta Cvetkoska

    2016-12-01

    Full Text Available We live in a complex world and managers of organizations are constantly facing numerous challenges. Good decisions, i.e., better outcomes for organizations, require use of the powerful discipline Operational Research (OR/Management Science (MS. Organizations applying this discipline have achieved significant benefits such as cost reduction, increased revenues, increased market share, higher quality, improved productivity, improved performance, better customer service, etc. The aim of this paper is to examine whether managers of micro, small and medium-sized enterprises in Macedonia use OR models for supporting decision-making processes, where OR models, methods and techniques are commonly used, and what benefits achieved in using quantitative OR models, methods and techniques. The survey was conducted using a questionnaire distributed electronically to 100 managers of micro, 100 managers of small and 100 managers of medium-sized enterprises. The questionnaires were answered completely by 93 managers of the micro, 73 managers of the small and 71 managers of the medium-sized enterprises, and the questionnaire responses were subsequently analyzed. The answers showed that decisions on running enterprises are made intuitively by 90% of managers of the micro, 78% of managers of the small, and 55% of managers of the medium-sized enterprises, while quantitative OR models for supporting the decision-making process are used by 10% of managers of the micro, 22% of managers of the small, and 45% of managers of the medium-sized enterprises. Applied in the micro, small and medium-sized enterprises are inventory models, time series analysis and forecasting, whereas micro and medium-sized enterprises rely on decision analysis. Small and medium-sized enterprises use break-even analysis, assignation, linear programming, and project management. The OR models and methods used in running the respective enterprises led to the following results: optimal inventory

  9. The development of internet based ship design support system for small and medium sized shipyards

    Directory of Open Access Journals (Sweden)

    Sung-Chul Shin

    2012-03-01

    Full Text Available In this paper, a prototype of ship basic planning system is implemented for the small and medium sized shipyards based on the internet technology and concurrent engineering concept. The system is designed from the user requirements. Consequently, standardized development environment and tools are selected. These tools are used for the system development to define and evaluate core application technologies. The system will contribute to increasing competitiveness of small and medium sized shipyards in the 21st century industrial en-vironment.

  10. Corporate Social Responsibility in Large and Medium-sized Companies in Poland

    Directory of Open Access Journals (Sweden)

    Maja Żychlewicz

    2016-06-01

    Full Text Available The paper aims to confront views on the CSR concept with the actual activities undertaken in this area by the large and medium-sized companies in Poland. The paper is enriched by the presentation of consumer opinions on CSR, by which it is possible to identify the purpose of implementing socially responsible activities in these entities. The thesis of the paper is that large and medium-sized enterprises in Poland recognize the expectations of consumers in the implementation of the concept of corporate social responsibility and at the same time feel the same need, but many of them have not taken any action in this respect so far.

  11. Environmental Promotion Law to Promote Entrepreneurship in Small and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Vicente René Encalada−Encarnación

    2016-12-01

    Full Text Available With the application of the law of promotion environmental in small and medium-sized entities (SMEs, in Ecuador is has attained improve the entrepreneurship business − formality required in terms of competitividad−, to the get that the venture business, contemplate the development and change of matrix productive, according to political of impact environmental constituted by the State Ecuadorian. This work synthesizes the results of application of the law of promotion environmental in small and medium-sized companies and is proposed recommendations for research related, that empower take best agreements and decisions based on the development business and reduction of the impact environmental.

  12. THE PREMISES OF STRATEGIC MARKETING PLANNING IMPLEMENTATION WITHIN SMALL AND MEDIUM SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Popescu Andrei

    2011-07-01

    Full Text Available The main purpose of the present paper is to identify the framework and the necessary conditions for the small and medium sized enterprises (SMEs to be able to adopt the strategic marketing planning. Also, the paper aims to underline the importance of the strategic marketing planning and the manner in which the SMEs can adopt, implement and operationalize the strategic marketing planning instruments, whose correct understanding and usage ensure the capacity to generate competitive advantage, the key element both from the perspective of the fierce competition and the perspective of the future development of the SMEs. Within SMEs the implementation of marketing becomes an evident requirment, mostly due to the relationship that these have with the market, thus, leading towards market orientation of the activities, a new approach developed by the marketing vision on managing the activities from these types of organizations. Regarded upon, from the marketing perspective, the activities from the SMEs, especially the marketing activities, cannot take place randomly. Resource allocation, a characteristic of these types of organizations, and the objectives with regards to superior customer needs satisfaction and economic efficiency maximization, claim thorough plannification and deployment of the activities in a sequence that represents the implementation of a strategy previously assumed. Within this framework, the strategic marketing planning appears as a complex process employing all scientific instruments that comprise segmentation, positioning and marketing mix. Utilizing the strategic marketing planning within SMEs depends to further extend on marketing integration; process directly related with a series of factors such as the nature of the market, development stage, product type, management quality and the influences of the marketing department of the SME. The implications onto the marketing activities from SMEs are reflected upon each strategic

  13. Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse Nucleus Accumbens

    Directory of Open Access Journals (Sweden)

    Giuseppe eGangarossa

    2013-02-01

    Full Text Available The nucleus accumbens (NAc is a critical brain region involved in many reward-related behaviors. The NAc comprises major compartments the core and the shell, which encompass several subterritories. GABAergic medium-sized spiny neurons (MSNs constitute the output neurons of the NAc core and shell. While the functional organization of the NAc core outputs resembles the one described for the dorsal striatum, a simple classification of the NAc shell neurons has been difficult to define due to the complexity of the compartmental segregation of cells. We used a variety of BAC transgenic mice expressing enhanced green fluorescence (EGFP or the Cre-recombinase (Cre under the control of the promoter of dopamine D1, D2, and D3 receptors and of adenosine A2a receptor to dissect the microanatomy of the NAc. Moreover, using various immunological markers we characterized in detail the distribution of MSNs in the mouse NAc. In addition, cell-type specific ERK phosphorylation in the NAc subterritories was analyzed following acute administration of SKF81297 (a D1R-like agonist, quinpirole (a D2R-like agonist, apomorphine (a non-selective DA receptor agonist, raclopride (a D2R-like antagonist, and psychostimulant drugs, including cocaine and d-amphetamine. Each drug generated a unique topography and cell-type specific activation of ERK in the NAc. Our results show the existence of marked differences in the receptor expression pattern and functional activation of MSNs within the shell subterritories. This study emphasizes the anatomical and functional heterogeneity of the NAc, which will have to be considered in its further study.

  14. Simulation of Supply-Chain Networks: A Source of Innovation and Competitive Advantage for Small and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Giacomo Liotta

    2012-11-01

    Full Text Available On a daily basis, enterprises of all sizes cope with the turbulence and volatility of market demands, cost variability, and severe pressure from globally distributed competitors. Managing uncertainty about future demand requirements and volumes in supply-chain networks has become a priority. One of the ways to deal with uncertainty is the utilization of simulation techniques and tools, which provide greater predictability of decision-making outcomes. For example, simulation has been widely applied in decision-making processes related to global logistics and production networks at the strategic, tactical, and operational levels, where it is used to predict the impact of decisions before their implementation in complex and uncertain environments. Large enterprises are inclined to use simulation tools whereas small and medium-sized enterprises seem to underestimate its advantages. The objective of this article is to emphasize the relevance of simulation for the design and management of supply-chain networks from the perspective of small and medium-sized firms.

  15. Ultrasound-guided percutaneous ethanol injection of small and medium-sized thyroid cysts with relatively small amounts of ethanol.

    Science.gov (United States)

    Halenka, Milan; Karasek, David; Frysak, Zdenek

    2015-09-01

    Ultrasound-guided percutaneous ethanol injection (US-guided PEI) is used in patients with recurring symptomatic thyroid cysts in whom simple drainage was not successful. It is an alternative non-surgical approach in patients refusing or at risk during surgery. US-guided PEI was performed in 33 patients, with a success rate of 100% and significantly decreased cyst volume after 1, 3 and 6 months after the last PEI compared with the initial volume. The mean number of PEI procedures was 1.5±0.7 with a mean 96% ethanol volume of 2.4±1.2 mL. In the entire group, the initial cyst volume was significantly reduced to the final volume at 6 months after PEI (10.82±5.03 mL vs. 0.78±0.84 mL; Pethanol was equal to 22.7±7.9% of the initial cyst volume. Our experiences confirm that small and medium-sized cysts may be successfully treated with relatively small amounts of ethanol. In case of medium-sized cysts, more PEI procedures were needed. Final reduction of complex cysts was achieved later. Apart from temporary localized pain, no serious complications were observed in most cases.

  16. Hedging Behavior in Small and Medium-sized Enterprises: The Role of Unobserved Heterogeneity

    NARCIS (Netherlands)

    Pennings, J.M.E.; Garcia, P.

    2004-01-01

    Abstract We investigate factors that drive derivative usage in small and medium-sized enterprises (SMEs). The influence of these factors on hedging behavior cannot a priori be assumed equal for all SMEs. To address this heterogeneity, a generalized mixture regression model is used which classifies

  17. Meaningfulness for creation of growth in Small- and Medium-sized enterprises

    DEFF Research Database (Denmark)

    Brink, Tove; Neville, Mette

    2016-01-01

    The research in this paper reveals how meaningfulness of growth can be created in Small- and Medium-sized Enterprises (SMEs). The research is conducted in a four-year period with 24 SMEs participating from different industry branches. The research is now in the late part of the 3rd. year starting...

  18. Small and Medium-Sized Information Technology Firms: Assessment of Non-Local Partnership Facilitators

    Science.gov (United States)

    Findikoglu, Melike Nur

    2012-01-01

    A two-phased qualitative study was conducted to explore the facilitators of non-local (i.e. domestic or international) partnerships formed by small- and medium-sized firms (SME). Rooted in trust, proximity and dynamic capabilities lenses, the study focused on behaviors of SMEs performing in dynamic, competitive and highly interlinked industry, the…

  19. Droplet model of plasma resonances in medium-size metal clusters

    Energy Technology Data Exchange (ETDEWEB)

    Iachello, F.; Lipparini, E. (Dipartimento di Fisica, Universita di Trento, 38050 Povo (Italy)); Ventura, A. (Comitato Nazionale per l' Energia Nucleare e le Energie Alternative, I-40138 Bologna (Italy))

    1992-02-15

    We study photon absorption and scattering by medium-size {ital N}=8--20 sodium clusters, making use of the interacting boson model to describe the coupling of plasma resonances to surface oscillations and deformations of a dropletlike structure. With reasonable assumptions on the nature of the plasma resonances and their couplings, we obtain an excellent description of the experimental photoabsorption data.

  20. Droplet model of plasma resonances in medium-size metal clusters

    Science.gov (United States)

    Iachello, F.; Lipparini, E.; Ventura, A.

    1992-02-01

    We study photon absorption and scattering by medium-size N=8-20 sodium clusters, making use of the interacting boson model to describe the coupling of plasma resonances to surface oscillations and deformations of a dropletlike structure. With reasonable assumptions on the nature of the plasma resonances and their couplings, we obtain an excellent description of the experimental photoabsorption data.

  1. Favouring Small and Medium Sized Enterprises with Directive 2014/24/EU

    DEFF Research Database (Denmark)

    Trybus, Martin; Andrecka, Marta

    2017-01-01

    This article argues that the four main measures introduced in the 2014 reform of the Procurement Directives to promote Small andMediumSized Enterprises (SMEs) cannot be classified as measures favouring SMEs. A measure favours SMEs when it compromises the main objectives of competition, non...

  2. The snoek Thyrsites atun is a medium-sized, pelagic predator (max ...

    African Journals Online (AJOL)

    spamer

    The snoek Thyrsites atun is a medium-sized, pelagic predator (max. size 9 kg, Nepgen 1979a) that inhabits the coastal waters of the temperate southern hemi- sphere (Kailola et al. 1993). Southern African snoek have been recorded from northern Angola to Algoa. Bay on the South African east coast, but are found.

  3. Expanding Partnerships for Small- and Medium-Sized Enterprises (SMEs) Needed: The Right Kind of Support.

    Science.gov (United States)

    Hlava, Marjorie M. K.

    1999-01-01

    Focuses on the support available for small- and medium-sized enterprises (SMEs). Outlines characteristics of SMEs and types of help available to SMEs from governments and big business. Identifies two problems related to contacts in the real world and the bureaucracy surrounding minority set-asides. Discusses the kinds of assistance entrepreneurs…

  4. Social responsibility of small and medium-sized business in Russia

    Directory of Open Access Journals (Sweden)

    A V Neverov

    2016-12-01

    Full Text Available Corporate social responsibility has become an important part of business activities of many organizations. Despite the fact that the corporate social responsibility as an institutionalized organizational management process has existed for more than 50 years, it has not yet received the deserved scientific attention, and its various aspects are still subject to debates. Given that small and medium-sized business organizations play an important role in the socio-economic development of the country, such a problem can become a significant barrier for increasing the efficiency of interaction of main actors and stakeholders of business activities in the country. Thus, it is crucial to study the priorities of small and medium-sized organizations in the corporate social responsibility field. The authors conducted an empirical exploratory study of the Russian small and medium-sized business organizations and found out that their representatives do not have a clear understanding of the directions and methods of implementing the social responsibility model. For instance, the standards developed for large organizations to implement the ideas of corporate social responsibility are too global and too costly for small and medium-sized businesses, however the latter in Russia still do not have their own technologies and algorithms for implementing an appropriate model of social responsibility (except for some types of charity and requirements to retrain workers, which are considered rather external claims.

  5. Innovation capabilities and challenges for energy smartdevelopment in medium sized European cities

    NARCIS (Netherlands)

    Lindhult, Erik; Campillo, J.; Dahlquist, E.; Read, S.A.

    2016-01-01

    Transition towards becoming Energy smart city integrating different areas of energy production, distribution and use in a community requires a spectrum of capabilities. The paper reports on findings from the EU planning project PLEEC, involving six medium sized European cities. The purpose of the

  6. New Balancing Equipment for Mass Production of Small and Medium-Sized Electrical Machines

    DEFF Research Database (Denmark)

    Argeseanu, Alin; Ritchie, Ewen; Leban, Krisztina Monika

    2010-01-01

    The level of vibration and noise is an important feature. It is good practice to explain the significance of the indicators of the quality of electrical machines. The mass production of small and medium-sized electrical machines demands speed (short typical measurement time), reliability...

  7. Current information technology needs of small to medium sized apparel manufacturers and contractors

    Energy Technology Data Exchange (ETDEWEB)

    Wipple, C.; Vosti, E.

    1997-11-01

    This report documents recent efforts of the American Textile Partnership (AMTEX) Demand Activated Manufacturing Architecture (DAMA) Project to address needs that are characterized of small to medium sized apparel manufactures and contractors. Background on the AMTEX/DAMA project and objectives for this specific efforts are discussed.

  8. Overview of progress in European medium sized tokamaks towards an integrated plasma-edge/wall solution

    DEFF Research Database (Denmark)

    Meyer, H.; Eich, T.; Beurskens, M.

    2017-01-01

    Integrating the plasma core performance with an edge and scrape-off layer (SOL) that leads to tolerable heat and particle loads on the wall is a major challenge. The new European medium size tokamak task force (EU-MST) coordinates research on ASDEX Upgrade (AUG), MAST and TCV. This multi-machine ...

  9. Implementation of Lean Six Sigma in small- and medium-sized manufacturing enterprises in the Netherlands

    NARCIS (Netherlands)

    Timans, W.; Antony, J.; Ahaus, K.; van Solingen, R.

    In this paper we provide an exploration and analysis of Lean Six Sigma (LSS) implementation in Dutch manufacturing/engineering small- and medium-sized enterprises (SMEs). Critical success factors (CSFs) and impeding factors are identified and analysed. Exploratory empirical evidence about LSS

  10. The Prospects and Instruments for Development of the Small and Medium-Sized Entrepreneurship in Ukraine

    Directory of Open Access Journals (Sweden)

    Parkhomenko Olena S.

    2017-09-01

    Full Text Available The article is concerned with defining the main problems in the sphere of small and medium-sized enterprises at the regional (on example of Kharkiv region and national levels, studying the prospects and instruments for development of small and medium-sized businesses in Ukraine. The main legislative and regulatory documents aimed at the development of the small and medium-sized sector of entrepreneurship have been provided. Also an analysis of the main expected accomplishments of the Program of facilitating the development of small and medium entrepreneurship in Kharkiv region in 2016-2020 and of the number of public institutions supporting entrepreneurship has been carried out. The main obstacles to small and medium-sized business development at both the regional and the national levels have been determined. The instruments for development of entrepreneurship sector have been grouped according to suggestions by representatives of the regional business association, public communities, banking sphere and other financial and credit institutions, experts-researchers, representatives of the public authorities, etc.

  11. An Agile Methodology for Implementing Service-Oriented Architecture in Small and Medium Sized Organizations

    Science.gov (United States)

    Laidlaw, Gregory

    2013-01-01

    The purpose of this study is to evaluate the use of Lean/Agile principles, using action research to develop and deploy new technology for Small and Medium sized enterprises. The research case was conducted at the Lapeer County Sheriff's Department and involves the initial deployment of a Service Oriented Architecture to alleviate the data…

  12. Key Influencing Factors behind Moodle Adoption in Irish Small to Medium Sized Higher Education Colleges

    Science.gov (United States)

    Walker, David; Livadas, Lelia; Miles, Gail

    2011-01-01

    This research investigated Irish Small to Medium Sized Educational Institutions (SMSEs) involved in Higher Education (HE) that adopted Moodle, the OSS (Open Source Software) course management system (CMS). As Moodle has only been adopted in the Irish HE sector in the last 5-7 years, this research crucially studied the attitudes of the SMSEs that…

  13. Supporting the E-Business Readiness of Small and Medium-Sized Enterprises: Approaches and Metrics.

    Science.gov (United States)

    Jutla, Dawn; Bodorik, Peter; Dhaliwal, Jasbir

    2002-01-01

    Presents a conceptual model for governments in creating a climate that facilitates the national adoption of e-business. Focuses on the needs of small and medium-sized enterprises, suggests measures to assess how a country is performing in providing a positive e-business climate, and provides examples from Canada, The Netherlands, Norway, and…

  14. Successful E-Learning in Small and Medium-Sized Enterprises

    Science.gov (United States)

    Paulsen, Morten Flate

    2009-01-01

    So far, e-learning has primarily been used when there are many learners involved. The up-front investments related to e-learning are relatively high, and may be perceived as prohibitive for small and medium-sized enterprises (SMEs). Some e-learning is, however, getting less expensive, and some e-learning models are more suited for small-scale…

  15. Barriers to Employee Training in Small and Medium Sized Enterprises: Insights and Evidences from Mauritius

    Science.gov (United States)

    Padachi, Kesseven; Bhiwajee, Soolakshna Lukea

    2016-01-01

    Purpose: Training is an important component of successful business concerns. However, although there is growing acceptance amongst scholars that small- and medium-sized enterprises (SMEs) are engines that drive economies across nations, through their contribution in terms of job creation and poverty reduction; extant research portray that these…

  16. Personnel role by implementing anti-crisis programs in small and medium-size enterprises

    Directory of Open Access Journals (Sweden)

    Pak Andrey Borisovitch

    2011-08-01

    Full Text Available To recover from crisis, small and medium-size enterprises have to develop anti-crisis plans and programs and to monitor the implementation process. The implementation efficiency is provided by the personnel which needs appraisal, motivation and development.

  17. Toward a Singleton Undergraduate Computer Graphics Course in Small and Medium-Sized Colleges

    Science.gov (United States)

    Shesh, Amit

    2013-01-01

    This article discusses the evolution of a single undergraduate computer graphics course over five semesters, driven by a primary question: if one could offer only one undergraduate course in graphics, what would it include? This constraint is relevant to many small and medium-sized colleges that lack resources, adequate expertise, and enrollment…

  18. Exploring influences on the cellular uptake of medium-sized silver nanoparticles into THP-1 cells

    NARCIS (Netherlands)

    Krystek, P.W.; Kettler, K.; van der Wagt, B.; de Jong, W.H.

    2015-01-01

    The evaluation of the uptake of nanomaterials by cells in vitro tests is of great relevance to understand potential toxicity mechanisms of nanomaterials. As an example, the uptake of medium-sized nanosilver (size range of 50 and 75. nm) was studied closely for a relevant human lung cell line

  19. Outcomes of facial artery musculomucosal flap for closure of small and medium sized fistula after clefts

    Directory of Open Access Journals (Sweden)

    Abdel Aziz Yehya

    2017-11-01

    Conclusion: FAMM flap is appropriate for reconstruction of small and medium sized fistula because of its reliability and versatility. The flap presents few complications and ensures adequate functional results after palatal fistula repair because of its nearly the same tissue like the palatal tissue.

  20. Bridging the Gap between Universities of Professional Education and Small- and Medium-Sized Enterprises

    NARCIS (Netherlands)

    Masurel, E.; Nijkamp, P.

    2011-01-01

    Improving the relationship between knowledge institutions (especially Universities of Professional Education, UPE) and Small-and Medium-sized Enterprises (SMEs) is one of the challenges of current economic policy. Innovation is an important aspect of this policy. However, the characteristics of both

  1. Energetic Communities : Planning support for sustainable energy transition in small- and medium-sized communities

    NARCIS (Netherlands)

    Sager-Klauß, C.V.

    2016-01-01

    Small- and medium-sized communities might prove to be game-changers in the overall energy transition because many problems have to be solved within their ambit. Urban planning is dealing with the numerous processes of urban change. Energy is a fairly new task to be addressed and many stakeholders

  2. Transformational and transactional leadership: does it work in small to medium-sized enterprises?

    NARCIS (Netherlands)

    Mesu, J.K.

    2013-01-01

    Using a sample of 755 employees who rated 121 supervisors within 50 Dutch small and medium-sized enterprises (SMEs), this dissertation intends to fill in some of the existing gaps in the literature. Firstly, by investigating whether the impact of transformational and transactional leadership extends

  3. Regulation of Small and Medium-Sized Business Development in Russia: Problems and Solutions

    Directory of Open Access Journals (Sweden)

    Lyudmila Yuryevna Bogachkova

    2015-12-01

    Full Text Available The authors prove that despite the active state policy carried out since the second half of the 2000s and aimed at supporting small and medium-sized business in the Russian Federation, the current level of development of this economic sector is insufficient. The present paper characterizes the modern structure of small and medium-sized business. The authors show that the main problems hindering its growth are conditioned by low market demand, large tax deductions, numerous administrative barriers, lack of funding and state support. On the basis of the official data of Russian Federal State Statistics Service on theresults of annual surveys of entrepreneurs, the authors revealed the factors that prevented innovation situation in the country have stable negative impact on MSB, while the impact of such factors as imperfect legal and regulatory framework, investment risks, low profitability and inadequate state of technological infrastructure is relatively nonsignificant. The authors describe systemwide and resource measures of state regulation of small and medium-sized business. The system-wide measures include preferential access to production facilities and equipment, special tax regimes, administrative control. The measures of resource support to entrepreneurs consist in subsidizing the lease payments and interest rates on loans for the modernization of production; grant support, the establishment of microfinance organizations and guarantee funds, the development of business support infrastructure. The authors describe the forms of these measures implementation in 2013 and the main directions of improving the state regulation of small and medium-sized business, including the reduction of tax burden and facilitation of taxation procedures, the reduction of administrative barriers and ensuring access of small and medium-sized enterprises to government orders and technological infrastructure.

  4. Raising medium-sized livestock and hepatitis risk: A national study in Indonesia

    Directory of Open Access Journals (Sweden)

    Maria Holly Herawati

    2012-07-01

    Full Text Available Latar belakang: Sanitasi lingkungan, termasuk kandang pemeliharaan ternak sedang, berpengaruh terhadap penyebaran penyakit hepatitis A dan E. Tujuan penelitian ini menilai lokasi kandang pemeliharaan ternak sedang berkaitan dengan risiko gejala hepatitis di beberapa propinsi dengan prevalensi hepatitis tinggi di Indonesia. Metode: Data berasal dari sebagian hasil Riset Kesehatan Dasar (Riskesdas tahun 2007 di Indonesia. Untuk penilaian ini, data yang dipakai berasal dari 12 propinsi dengan prevalensi tinggi (0,6% hepatitis di Indonesia, dan dipilih hanya subjek yang tidak memelihara ternak serta hanya yang memelihara ternak sedang. Subjek hepatitis adalah responden yang pada saat wawancara mengatakan pernah mempunyai gejala hepatitis atau pernah di diagnosis menderita hepatitis oleh dokter atau paramedik dalam kurun waktu 12 bulan terakhir. Hasil: Dari 141.291 subjek, 1.257 (0,8% menderita hepatitis. Pada umumnya yang memelihara ternak sedang berisiko 86% lebih banyak terkena hepatitis dibandingkan dengan yang tidak memelihara  ternak [rasio odds suaian (ORa=1,86; 95% interval kepercayaan (CI=1,61-2,09]. Risiko tertinggi (2 kali lipat terkena hepatitis terjadi di antara subjek yang mengandangkan ternak sedang di dalam rumah (ORa=1,98; 95% CI=1,47-2,66, sedangkan risiko terkecil (38% lebih besar terkena hepatitis terjadi di antara yang mengandangkan ternak sedangnya di luar luar rumah dibandingkan dengan tidak memelihara ternak sedang (ORa=1,38; 95% CI=1,14-1,67 dibandingkan dengan tidak memelihara ternak. Kesimpulan: Kandang di luar rumah untuk meliharaan ternak sedang yang paling kecil menyebabkan risiko hepatitis. (Health Science Indones 2011;2:14-20   Abstract Background: Environmental sanitation, among others raising medium-sized livestock, affect the spread of hepatitis A and E. This paper presents an assessment of relation between place of raising medium-sized livestock and risk of hepatitis in high prevalence endemic hepatitis provinces

  5. Urban agglomerations and transformations of medium-sized towns in Poland

    Directory of Open Access Journals (Sweden)

    Runge Anna

    2016-09-01

    Full Text Available This analysis investigates medium-sized towns in Poland, i.e. those with a population between 20–100 thousand, located up to 100 km away from the main city of the agglomeration. The aim of this article is to compare the level of socio-economic development of Polish towns depending on their location in relation to the main city in the largest agglomerations in 1998 and 2013. Three zones of distance from the main city of each agglomeration have been taken into consideration: a. the inner zone, reaching up to 25 km from the main city; b. the outer zone located at a distance of 25 to 50 km from the main city, and c. the peripheral zone, located at a distance of 50 to 100 km from the main city and including the medium-size towns located outside the agglomeration system. This analysis of the distribution of medium-sized towns and their level of socio-economic development has shown various levels of changes which depend on the distance from the main city of the agglomeration. In 1998, the highest level of development of the medium-sized towns was recorded in towns outside of these agglomeration systems, i.e. those located most remotely from the main city (peripheral zone. Most of the medium-sized towns are situated at a distance of 50–100 km from Warszawa, Kraków, Łódź, Lublin, Gdańsk and have developed their own local, or even regional labour markets and some of them have even provided administrative functions in the past as voivodeship capitals. Only in the Poznań agglomeration, the level of development of medium-sized towns was higher in the immediate surroundings of the main city (25 km. The medium-sized towns in all zones of the distance from the main city in the Wrocław agglomeration represented a similar level of development. By 2013, the level of development of the medium-sized towns in the peripheral zone in all investigated settlement systems had decreased, with a significant improvement in the level of development of the towns in

  6. Management instrumentarium of innovation development of medium-sized industrial enterprises

    Directory of Open Access Journals (Sweden)

    Ismagilova L.

    2017-01-01

    Full Text Available The article is devoted to the development management of industrial enterprises related to medium-sized businesses and working in the field of product innovation. In the article there were investigated the methods and management features, the factors, constraining innovation processes in industrial companies. The theoretical background of solving innovation development and maintaining economic stability contradictions were identified. The results of the comparative assessment of small and medium-sized enterprises were unveiled. In paper there were revealed the features and benefits of the transition to the innovative products. A method of positioning matrix and the typology of enterprises in terms of economic sustainability and innovation were proposed. There was worked out a graph-analytical management tool for middle-sized industrial enterprises on the basis of a balance of innovative activity and economic sustainability. For a given industrial enterprise there was formed an effectively balanced portfolio of products at different stages of the life cycle.

  7. Design of an interdisciplinary engineering elective scoped around collaboration with Small Medium Sized enterprises (SME)

    DEFF Research Database (Denmark)

    Christiansen, Nynne Budtz; Ulrich, Mai-Mai; Pontoppidan, Maja Lund

    2014-01-01

    of a compulsory 10 ECTS element with focus on interdisciplinary and industry collaboration for all Bachelors of Engineering at The Technical University of Denmark in 2016. As collaboration partner the elective has chosen to work with small and medium sized enterprises (SME) as more than half of the value added...... a real life setting elective course, involving small and medium sized enterprises (SME) in engineering education. How do you engage with companies without compromising the learning outcome? How you manage the expectation from the companies and still maintaining the student responsibility for the problem.......5 year long engineering education building on engineering industry practice as its core. All BEng educations build on the CDIO (Conceive-Design-Implement-Operate) as the overall teaching paradigm3. The development has been funded by the Danish Foundation for Entrepreneurship, and is seen as an experiment...

  8. Surveillance of medium-size dams; Surveillance des barrages de taille moyenne

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    French hydro-power buildings belong to the government and are retroceded by the licence holder when the granting delay comes to an end. Experience has shown that less care is given by licence holders to the maintenance of medium-size dams that to big dams. For this reason, the French Ministry of Industry decided to harmonize and standardize the surveillance practices of medium-size dams. A circular was signed on May 23, 1997 which concerns the 10 to 20 m height dams with water reservoir volumes lower than the H{sup 2} x V{sup 0.5} criterion which is an evaluation of the potential risk of the dam. The surveillance modalities concern: the construction, the licence holder file, the first filling up, the operation, and the periodical safety inspections. (J.S.)

  9. The causal effect of board size in the performance of small and medium-sized firms

    DEFF Research Database (Denmark)

    Bennedsen, Morten; Kongsted, Hans Christian; Meisner Nielsen, Kasper

    2008-01-01

    correlation between family size and board size and show this correlation to be driven by firms where the CEO's relatives serve on the board. Second, we find empirical evidence of a small adverse board size effect driven by the minority of small and medium-sized firms that are characterized by having......Empirical studies of large publicly traded firms have shown a robust negative relationship between board size and firm performance. The evidence on small and medium-sized firms is less clear; we show that existing work has been incomplete in analyzing the causal relationship due to weak...... identification strategies. Using a rich data set of almost 7000 closely held corporations we provide a causal analysis of board size effects on firm performance: We use a novel instrument given by the number of children of the chief executive officer (CEO) of the firms. First, we find a strong positive...

  10. Analysis of energy-efficiency investment decisions by small and medium-sized manufacturers

    Energy Technology Data Exchange (ETDEWEB)

    Woodruff, M.G.; Roop, J.M.; Seely, H.E. [Pacific Northwest National Lab., Richland, WA (United States); Muller, M.R. [Rutgers--the State Univ., New Brunswick, NJ (United States); Jones, T.W. [Alliance to Save Energy, Washington, DC (United States); Dowd, J. [USDOE, Washington, DC (United States)

    1996-05-01

    This report highlights the results of a comprehensive analysis of investment decisions regarding energy-efficiency measures at small and medium-sized manufacturing plants. The analysis is based on the experiences of companies participating in the DOE Industrial Assessment Center (IAC) program. The IAC program is a network of university-based centers that provides energy and waste assessments to small and medium-sized manufacturing plants. The purposes of this report are to do the following: (1) Examine what the data collected reveal about patterns of implementation of recommended energy- efficiency measures, (2) Evaluate how various factors, such as the type of industry, the characteristics of the manufacturing plants, or the cost of the measures, appear to effect implementation rates, (3) Examine reasons why recommended energy-saving measures are accepted or rejected.

  11. Attractive and climate-friendly medium-sized cities; Attraktive og klimavennlige mellomstore byer

    Energy Technology Data Exchange (ETDEWEB)

    Tennoey, Aud

    2012-07-01

    Ministry of the Environment (MD) wanted an overview of current knowledge of climate-friendly and attractive urban development in medium-sized cities (10 - 50 000 inhabitants). This report presents and discusses knowledge between major cities' situation and challenges of land use and transport development to reduce car traffic and greenhouse gas emissions and on urban development for more attractive cities. A main conclusion is that there are major gaps in knowledge and opportunities for improvement. If those covered will be far better opportunities for planners, local authorities and others may be able to contribute to more climate-friendly and attractive medium-sized cities.The report is part of the project Comprehensive information pack for the status of knowledge from research on urban development. The project has also prepared a report entitled Planning for attractive urban environment. The reports are intended to complement each other and should be seen in context.(eb)

  12. Practical application of Earned Value Method to evaluation of progress status of medium size construction projects

    Science.gov (United States)

    Czemplik, A.

    2017-10-01

    Earned Value Method (EVM) became in recent years the global standard for describing of the current time/budget status of engineering projects. It is the most preferred tool by international construction arbitrage bodies, in case the advancement of the construction project for a given date must be defined in a commonly recognizable way. Application of the method in every day site practice needs 2-3 people team dedicated just for that task, so the EVM it is used rather for large projects. However, using of the method in its reduced scale, as presented in the paper, can be fully economic also for medium size construction projects and provides set of information that can be very helpful for site managers in decision making processes. The numerical example of EVM used for medium size apartment construction project has been presented in the paper to illustrate the proposed concept of using EVM to the reduced extend.

  13. Karyotypes of some medium-sized Dytiscidae (Agabinae and Colymbetinae) (Coleoptera).

    Science.gov (United States)

    Angus, Robert B; Clery, Molly J; Carter, Jodie C; Wenczek, Daniel E

    2013-01-01

    An account is given of the karyotypes of 29 species of medium sized Dytiscidae (Coleoptera). Of the 20 species of Agabus Leach, 1817, 18 have karyotypes comprising 21 pairs of autosomes and sex chromosomes which are either X0(♂) or XX (♀). These species are Agabus serricornis (Paykull, 1799), Agabus labiatus (Brahm, 1791), Agabus congener (Thunberg, 1794), Agabus lapponicus (Thomson, 1867), Agabus thomsoni (J. Sahlberg, 1871), Agabus confinis (Gyllenhal, 1808), Agabus sturmii (Gyllenhal, 1808), Agabus bipustulatus (Linnaeus, 1767), Agabus nevadensis Håkan Lindberg, 1939, Agabus wollastoni Sharp, 1882, Agabus melanarius Aubé, 1837, Agabus biguttatus (Olivier, 1795), Agabus binotatus Aubé, 1837, Agabus affinis (Paykull, 1798), Agabus unguicularis (Thomson, 1867), Agabus ramblae Millan & Ribera, 2001, Agabus conspersus (Marsham, 1802) and Agabus nebulosus (Forster, 1771). However two species, Agabus infuscatus Aubé, 1838 and Agabus adpressus Aubé, 1837, have developed a neo-XY system, with karyotypes comprising 21 pairs of autosomes and XY sex chromosomes (♂). No chromosomal differences have been detected between typical Agabus bipustulatus and Agabus bipustulatus var. solieri Aubé, 1837, nor have any been found between the three species of the Agabus bipustulatus complex (Agabus bipustulatus, Agabus nevadensis and Agabus wollastoni). The four species of Colymbetes Clairville, 1806, Colymbetes fuscus (Linnaeus, 1758), Colymbetes paykulli Erichson, 1837, Colymbetes piceus Klug, 1834 and Colymbetes striatus (Linnaeus, 1758) have karyotypes comprising 20 pairs of autosomes and sex chromosomes which are X0 (♂), XX (♀). Two of the species of Rhantus Dejean, 1833, Rhantus exsoletus (Forster, 1771) and Rhantus suturellus (Harris, 1828) have karyotypes comprising 20 pairs of autosomes and X0/XX sex chromosomes, but the other three species, Rhantus grapii (Gyllenhal, 1808), Rhantus frontalis (Marsham, 1802) and Rhantus suturalis (Macleay, 1825) have 22 pairs of

  14. Karyotypes of some medium-sized Dytiscidae (Agabinae and Colymbetinae (Coleoptera

    Directory of Open Access Journals (Sweden)

    Robert Angus

    2013-06-01

    Full Text Available An account is given of the karyotypes of 29 species of medium sized Dytiscidae (Coleoptera. Of the 20 species of Agabus Leach, 1817, 18 have karyotypes comprising 21 pairs of autosomes and sex chromosomes which are either X0(♂ or XX (♀. These species are A. serricornis (Paykull, 1799, A. labiatus (Brahm, 1791, A. congener (Thunberg, 1794, A. lapponicus (Thomson, 1867, A. thomsoni (J. Sahlberg, 1871, A. confinis (Gyllenhal, 1808, A. sturmii (Gyllenhal, 1808, A. bipustulatus (Linnaeus, 1767, A. nevadensis Håkan Lindberg, 1939, A. wollastoni Sharp, 1882, A. melanarius Aubé, 1837, A. biguttatus (Olivier, 1795, A. binotatus Aubé, 1837, A. affinis (Paykull, 1798, A. unguicularis (Thomson, 1867, A. ramblae Millan & Ribera, 2001, A. conspersus (Marsham, 1802 and A. nebulosus (Forster, 1771. However two species, A. infuscatus Aubé, 1838 and A. adpressus Aubé, 1837, have developed a neo-XY system, with karyotypes comprising 21 pairs of autosomes and XY sex chromosomes (♂. No chromosomal differences have been detected between typical A. bipustulatus and A. bipustulatus var. solieri Aubé, 1837, nor have any been found between the three species of the A. bipustulatus complex (A. bipustulatus, A. nevadensis and A. wollastoni. The four species of Colymbetes Clairville, 1806, C. fuscus (Linnaeus, 1758, C. paykulli Erichson, 1837, C. piceus Klug, 1834 and C. striatus (Linnaeus, 1758 have karyotypes comprising 20 pairs of autosomes and sex chromosomes which are X0 (♂, XX (♀. Two of the species of Rhantus Dejean, 1833, R. exsoletus (Forster, 1771 and R. suturellus (Harris, 1828 have karyotypes comprising 20 pairs of autosomes and X0/XX sex chromosomes, but the other three species, R. grapii (Gyllenhal, 1808, R. frontalis (Marsham, 1802 and R. suturalis (Macleay, 1825 have 22 pairs of autosomes and X0/XX sex chromosomes. Agabus congener and Rhantus suturellus may have one B-chromosome. Nine of the species have previously published karyotype data but

  15. Urbanization alters communities of flying arthropods in parks and gardens of a medium-sized city

    OpenAIRE

    Edward Lagucki; Justin D. Burdine; McCluney, Kevin E.

    2017-01-01

    Urbanization transforms undeveloped landscapes into built environments, causing changes in communities and ecological processes. Flying arthropods play important roles in these processes as pollinators, decomposers, and predators, and can be important in structuring food webs. The goal of this study was to identify associations between urbanization and the composition of communities of flying (and floating) arthropods within gardens and parks in a medium-sized mesic city. We predicted that fl...

  16. Inter-firm networking propensity in small and medium-sized enterprises (SMEs)

    OpenAIRE

    Nkongolo-Bakenda, Jean-Marie

    2002-01-01

    In the past decade, market globalization has not only been a threat for small and medium-sized enterprises (SMEs), but also an opportunity to expand their activities in many countries (Murphy and al., 1991). In fact, some of SMEs are worldwide leaders in their sectors (Simon, 1990; Entreprise, 1995). Moreover, few of these worldwide SME leaders started businesses directly on an international level (Christensen, 1991; Brush, 1992; McDougall and al., 1994). This suggests that these SMEs use man...

  17. The impact of finance on the performance of Thai manufacturing small and medium-sized enterprises

    OpenAIRE

    Amornkitvikai, Yot; Charles HARVIE

    2016-01-01

    This study sheds light on small and medium-sized enterprise (SME) financing and its performance in Thailand. It elaborates on the key sources of finance existing for Thai manufacturing SMEs and their importance for SME performance as measured by technical efficiency, export performance, and technological innovation. This study also examines the key factors enhancing SME access to external finance. Our results confirm that retained earnings are crucial to increase SME technical efficiency, but...

  18. Modelling of the costs of decision support for small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Viera Tomišová

    2017-01-01

    Full Text Available The support of decision-making activities in small and medium-sized enterprises (SME has its specific features. When suggesting steps for the implementation of decision-support tools in the enterprise, we identified two main ways of decision-making support based on the data analysis: ERP (Enterprise Resource Planning without BI (Business Intelligence and ERP with BI. In our contribution, we present costs models of both mentioned decision support systems and their practical interpretation.

  19. Rational approach for the management of a medium size bridge stock

    OpenAIRE

    Brühwiler, E.

    2008-01-01

    Infrastructure managers of medium size bridge stocks are being faced with the task of approximating short, mid to long term financial needs for their infrastructure. This task is particularly demanding due to the lack of relevant information, in particular in forecasting bridge condition and intervention costs. It can, therefore, be beneficial to make cost estimations based on structure types and present condition evaluation. In this article a rational approach for the management of the mediu...

  20. Manufacturing strategy formulation, leadership style and organisational culture in small and medium-sized enterprises

    OpenAIRE

    Löfving, Malin; Säfsten, Kristina; Winroth, Mats

    2016-01-01

    This study encourages an increased focus on managerial and organisational issues in manufacturing strategy formulation. The study investigates the relationship between manufacturing strategy formulation, leadership style and organisational culture in small and medium-sized enterprises (SMEs). Manufacturing strategy formulation is studied in three cases, and it is found that the formulation is different in each case. Leadership style is more visible than organisational culture in manufacturing...

  1. Impact of Female Leadership on Employee engagement in German small and medium-sized Family Companies

    OpenAIRE

    Rittinger, Katharina

    2014-01-01

    Due to the demographic change, German small and medium-sized family companies lack skilled employees. As a high level of employee engagement (EE) can help retaining skilled employees, engaging leaders are needed. The aim of this thesis was to analyse, if women are able to have a positive impact on employee engagement due to their leadership style. Qualitative theoretic information was gathered from academic literature. Latest professional journals and studies were used to give an insight ...

  2. Financial and Tax Management in Small and Medium Sized Industrial Enterprises

    Science.gov (United States)

    Bestvinová, Viera; Homokyová, Mária; Horváthová, Martina

    2012-12-01

    Target of this paper was to evaluate the importance of small and medium sized enterprises (SMEs) in Slovakia and to determine the application of financial and tax management in this type of enterprises. The results of our findings confirm that SMEs have an important role in Slovakia, and also that especially small businesses have little or no experience with the application of financial and tax management. Therefore the paper contains recommendations for financial and tax management of SMEs.

  3. Open innovation for small and medium sized enterprises: Ways to develop excellence

    OpenAIRE

    Spitzley, Anne; Rogowski, Thorsten; Garibaldo, Francesco

    2007-01-01

    The capability to innovate is the most critical element in sustaining competitiveness. Most big companies already are equipped with instruments and experience in innovation management but small and medium sized enterprises in contrast only have basic access to these instruments and often are faced with incompatibility of these instruments with their needs. For the strategic and operative planning, innovation processes and for project realisation, these tools are lacking. Furthermore, many too...

  4. Dynamics of innovation and internationalization among small and medium-sized enterprises in Viet Nam

    OpenAIRE

    Trinh, Long Q.

    2016-01-01

    This paper examines the bidirectional causality between innovation and internationalization in the context of developing countries. Using a dynamic bivariate probit model and adopting a broad definition of internationalization, this paper analyzes these issues using a panel dataset of small and medium-sized enterprises in Viet Nam. The results show a high persistence in process and product innovations and internationalization decisions. Furthermore, we find that, for non-micro firms, past int...

  5. JOB FUNCTION AND GENDER AS DETERMINANTS OF EMPLOYEE REMUNERATION IN THE SMALL AND MEDIUM SIZED ORGNANIZATIONS

    OpenAIRE

    Frans Maloa

    2015-01-01

    The size and fairness of gaps in employee remuneration are difficult to prove because of the uniqueness of the determinants of employee remuneration in different organisations. The purpose of the research on which this article is based was to review the distribution of employee remuneration across categories of job function and gender in South African small to medium-sized organisations. A purposive sampling method was used and categorical multiple regression analysis was performed. The overa...

  6. Mapping Small and Medium Sized Town in Europe: Classifications, Spatial Trends and Ontological Issues

    OpenAIRE

    Russo, Antonio

    2014-01-01

    This paper presents the various analytical steps and methods which have led to the creation of a geodatabase of urban settlements in Europe based on the integration of contiguous 1x1 square km. grid cells with specific population thresholds, and the delimitation and classification of those among them that are considered "small and medium-sized towns" (SMST) in coherence with the standard classification already produced by organisms such as DG Regio and OECD. This exercise has been one of the ...

  7. Role of Relationship Marketing in Small and Medium-Sized Entreprises

    OpenAIRE

    Ružica Butigan; Ivana Mahnić

    2011-01-01

    Along with marketing, small and medium enterprises (SMEs) are commonly associated in literature with relationship marketing which results in marketing networks. This paper examines the specific characteristics that differentiate large companies from small and medium-sized enterprises, and the reasons that prevent SMEs from engaging in traditional marketing within the scope of marketing mix. The paper also shows that the key characteristic which distinguishes small from large companies is a pr...

  8. Employee Motivation Problems and Countermeasures in Chinese Small and Medium Sized Private Enterprises

    OpenAIRE

    Tong, Jia

    2013-01-01

    As business competition among enterprises sharply increases, many small and medium-sized Chinese private enterprises which were thought to have great prospects were pushed out of the market. One reason of their failure is that lacking of scientific employee motivation system restricts the development of the business. Employee motivation, as an important business method, has become more and more important in the enterprises modern management system. An effective employee motivation system can ...

  9. Modelling of the costs of decision support for small and medium-sized enterprises

    OpenAIRE

    Viera Tomišová; Ján Hudec

    2017-01-01

    The support of decision-making activities in small and medium-sized enterprises (SME) has its specific features. When suggesting steps for the implementation of decision-support tools in the enterprise, we identified two main ways of decision-making support based on the data analysis: ERP (Enterprise Resource Planning) without BI (Business Intelligence) and ERP with BI. In our contribution, we present costs models of both mentioned decision support systems and their practical interpretation.

  10. A primer on governance and performance in small and medium-sized enterprises

    OpenAIRE

    Yacuzzi, Enrique

    2005-01-01

    This paper is a primer on corporate performance, corporate governance, and their interrelationships and measurement systems, with particular focus on Small and Medium- Sized Enterprises (SMEs). This is the first report of a larger on going research project. In the domain of performance measurement the paper describes the trend from financial to non-financial measures, as well as a taxonomy of measures and the impact of the TQM movement on measurement practices. In the domain of governance, go...

  11. The Internationalization Process of Mature Danish Small and Medium-Sized Enterprises

    OpenAIRE

    Myhre, Malene

    2017-01-01

    Small and medium-sized enterprises (SMEs) are important to growth, economic development, and job creation in many nations, and especially in small countries like Denmark. According to Statistics Denmark, there are roughly 300,000 active companies in Denmark. Of these, 99.4% are classified as SMEs. International trade is important for small countries, where the economy as a rule is closely integrated (both economically and financially) with the rest of the world. Despite the rec...

  12. Small- and Medium-Sized Commercial Building Monitoring and Controls Needs: A Scoping Study

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Underhill, Ronald M.; Goddard, James K.; Taasevigen, Danny J.; Piette, M. A.; Granderson, J.; Brown, Rich E.; Lanzisera, Steven M.; Kuruganti, T.

    2012-10-31

    Buildings consume over 40% of the total energy consumption in the U.S. A significant portion of the energy consumed in buildings is wasted because of the lack of controls or the inability to use existing building automation systems (BASs) properly. Much of the waste occurs because of our inability to manage and controls buildings efficiently. Over 90% of the buildings are either small-size (<5,000 sf) or medium-size (between 5,000 sf and 50,000 sf); these buildings currently do not use BASs to monitor and control their building systems from a central location. According to Commercial Building Energy Consumption Survey (CBECS), about 10% of the buildings in the U.S. use BASs or central controls to manage their building system operations. Buildings that use BASs are typically large (>100,000 sf). Lawrence Berkeley National Laboratory (LBNL), Oak Ridge National Laboratory (ORNL) and Pacific Northwest National Laboratory (PNNL) were asked by the U.S. Department of Energy’s (DOE’s) Building Technologies Program (BTP) to identify monitoring and control needs for small- and medium-sized commercial buildings and recommend possible solutions. This study documents the needs and solutions for small- and medium-sized buildings.

  13. Energetic Communities: Planning support for sustainable energy transition in small- and medium-sized communities

    Directory of Open Access Journals (Sweden)

    Christina Valeska Sager-Klauss

    2016-04-01

    Full Text Available The necessity for transition in the energy sector is beyond dispute and high on the political agendas. Climate change, the depletion of fossil fuels and the vulnerability of economies to resource speculation and unreliable political systems in the producing countries lay path for a broad implementation of smart alternative solutions. This means the integration of more sustainable renewable energy sources in the existing supply structures or the displacement of existing systems by new ones. Cities and communities are central players in the energy transition process. Energy demand is determined by the built environment. Renewable energy production needs space. The conflicts between different interest groups often break out in the context of local implementation measures that affect urban planning and the appearance of landscapes.Small- and medium-sized communities might prove to be game-changers in the overall energy transition because many problems have to be solved within their ambit. Urban planning is dealing with the numerous processes of urban change. Energy is a fairly new task to be addressed and many stakeholders lack experience and criteria for strategic decision making. After a period of fierce determination to turn the wheel against climate change, it seems that there is a growing resignation among politicians, planners and the public because some things have not turned out the way we’d expected and the hope for quick solutions fades. Rebound-effects seem to eat up the savings to a good extent, and alternative ideas of how sustainable energy systems may be put into place have not yet been persuasive in many cases. Energy systems have proved to be complex. They are still perceived to be important but in practice there is a growing uneasiness about the right steps to take. The overarching research question of this thesis is: What do decision makers in smalland medium-sized communities need to become more successful in implementing

  14. Energetic Communities: Planning support for sustainable energy transition in small- and medium-sized communities

    Directory of Open Access Journals (Sweden)

    Christina Valeska Sager-Klauss

    2016-04-01

    Full Text Available The necessity for transition in the energy sector is beyond dispute and high on the political agendas. Climate change, the depletion of fossil fuels and the vulnerability of economies to resource speculation and unreliable political systems in the producing countries lay path for a broad implementation of smart alternative solutions. This means the integration of more sustainable renewable energy sources in the existing supply structures or the displacement of existing systems by new ones. Cities and communities are central players in the energy transition process. Energy demand is determined by the built environment. Renewable energy production needs space. The conflicts between different interest groups often break out in the context of local implementation measures that affect urban planning and the appearance of landscapes. Small- and medium-sized communities might prove to be game-changers in the overall energy transition because many problems have to be solved within their ambit. Urban planning is dealing with the numerous processes of urban change. Energy is a fairly new task to be addressed and many stakeholders lack experience and criteria for strategic decision making. After a period of fierce determination to turn the wheel against climate change, it seems that there is a growing resignation among politicians, planners and the public because some things have not turned out the way we’d expected and the hope for quick solutions fades. Rebound-effects seem to eat up the savings to a good extent, and alternative ideas of how sustainable energy systems may be put into place have not yet been persuasive in many cases. Energy systems have proved to be complex. They are still perceived to be important but in practice there is a growing uneasiness about the right steps to take. The overarching research question of this thesis is: What do decision makers in smalland medium-sized communities need to become more successful in implementing

  15. A meta-analysis of different HR-enhancing practices and performance of small and medium sized firms

    NARCIS (Netherlands)

    Rauch, Andreas; Hatak, Isabella

    2016-01-01

    The role of human capital has received considerable attention in research on small and medium sized firms. However, much uncertainty remains as to how practices that enhance human resources (HR) affect the performance of small and medium sized firms, whether some practices have stronger effects than

  16. Compatibility of the IFRS for Small and Medium-sized Entities and the new EU-Accounting Directive

    Directory of Open Access Journals (Sweden)

    Gerrit Kaufhold

    2015-01-01

    Full Text Available The new EU-Accounting Directive of 26 June 2013 (DIRECTIVE 2013/34/EU has the intention to harmonize the accounting and financial reporting of enterprises in the European Union. “Think small first” is the central principle in the new EU-Accounting Directive and the new regulations have to be adopted in the laws of European member states by 20 July 2015. The International Financial Reporting Standard for Small and Medium-sized Entities (IFRS for SMEs was published in 2009 by the International Accounting Standards Board (IASB. The IASB intended to create simplified international financial reporting standards for the special needs of smaller and medium-sized enterprise. The IASB completed in May 2015 a comprehensive review of the IFRS for SMEs and made amendments to the Standard. The revised version of the IFRS for SMEs will be issued in the last quarter of 2015. The aim of the paper is to analyze the compatibility of the IFRS for SMEs and the new EU- Accounting Directive and the problems in connection with the harmonization of the European accounting legislation especially in Germany. Based on the results of the research most of the former incompatibilities could be removed, but the remaining complexity of the IFRS for SMEs and the lack of an option for the member states to adopt the IFRS for SMEs as an accounting and reporting standard besides or instead their local accounting principles will prevent the wide use of the IFRS for SMEs in Germany and in other member states of the European Union.

  17. A 10-step safety management framework for construction small and medium-sized enterprises.

    Science.gov (United States)

    Gunduz, Murat; Laitinen, Heikki

    2017-09-01

    It is of great importance to develop an occupational health and safety management system (OHS MS) to form a systemized approach to improve health and safety. It is a known fact that thousands of accidents and injuries occur in the construction industry. Most of these accidents occur in small and medium-sized enterprises (SMEs). This article provides a 10-step user-friendly OHS MS for the construction industry. A quantitative OHS MS indexing method is also introduced in the article. The practical application of the system to real SMEs and its promising results are also presented.

  18. Energy coservation status and needs: medium-sized commercial/industrial firms

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-01

    The potential for conserving energy by Seattle City Light's commercial/industrial customers is investigated. The results of the study will help SCL and others to provide energy- and money-saving help to their medium-sized business customers. Fifty in-person interviews of firms within the SCL area and 102 mailed questionnaires from customers outside the area in Washington and Oregon were analyzed. Researchers found that many steps requiring little cost have been implemented, but instituting further hard conservation measures such as new machinery, retrofitting, or changes in machine operations are lacking. (MCW)

  19. Cogeneration through small and medium sized gas turbines in Italy: Marketing survey

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, A.; Schieppati, P.

    1992-12-01

    In Italy, the use of cogeneration systems by private industrial concerns has greatly increased in the early 90's. The successful technological development of highly efficient low and medium sized gas turbines and the successful application of cogenerated power to a number of industrial processes, favourable legislation and financial incentives on the part of the Italian Government, especially interested in promoting energy conservation and the use of natural gas as an alternative to petroleum, as well as, fast payback periods for such investments are amongst the major regions for the growing demand for this type of power system alternative in Italy.

  20. Bank Size and Small- and Medium-sized Enterprise (SME) Lending: Evidence from China

    Science.gov (United States)

    SHEN, YAN; SHEN, MINGGAO; XU, ZHONG; BAI, YING

    2014-01-01

    Summary Using panel data collected in 2005, we evaluate how bank size, discretion over credit, incentive schemes, competition, and the institutional environment affect lending to small- and medium-sized enterprises in China. We deal with the endogeneity problem using instrumental variables, and a reduced-form approach is also applied to allow for weak instruments in estimation. We find that total bank asset is an insignificant factor for banks’ decision on small- and medium-enterprise (SME) lending, but more local lending authority, more competition, carefully designed incentive schemes, and stronger law enforcement encourage commercial banks to lend to SMEs. PMID:26052179

  1. Occupational safety and health in small and medium-sized enterprises during social and economic transformation.

    Science.gov (United States)

    Koradecka, D

    2001-01-01

    Small and medium-sized enterprises (SMEs) in Central and Eastern Europe at the turn of the 1980s and 1990s were characterised by many people exposed to hazardous working conditions. Statistics recorded a considerable increase in the number of occupational diseases. They also showed that it was more dangerous to work for a small company. The transition from planned to market economy has brought about an increase in the number of SMEs in Poland. Data on them are provided. The role of the Central Institute for Labour Protection in studying SMEs is presented. A pilot study of employers and employees is discussed.

  2. Overview of progress in European medium sized tokamaks towards an integrated plasma-edge/wall solution

    OpenAIRE

    Meyer, H.; Eich, T.; Citrin, J.; Classen, I.; Hogeweij, D.; Jaulmes, F.; Kappatou, A.; Van den Brand, H.; Vanovac, B.; Vijvers, W. A. J.; Westerhof, E.; et al.

    2017-01-01

    Integrating the plasma core performance with an edge and scrape-off layer (SOL) that leads to tolerable heat and particle loads on the wall is a major challenge. The new European medium size tokamak task force (EU-MST) coordinates research on ASDEX Upgrade (AUG), MAST and TCV. This multi-machine approach within EU-MST, covering a wide parameter range, is instrumental to progress in the field, as ITER and DEMO core/pedestal and SOL parameters are not achievable simultaneously in present day de...

  3. IMPACT OF INNOVATION UPON THE DYNAMICS OF ROMANIAN SMALL AND MEDIUM SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    JEANINA CIUREA

    2013-10-01

    Full Text Available Innovation is central to economic growth, as the area in which it develops takes the whole sphere of economic activities: product, process, service, organization, marketing, hence the economic effects they may cause. Creating "innovative enterprises", giving tax cuts to certain periods of time, preferential loans, creating funds 'risk capital' are just some of the measures that European countries which already apply and Romania, willing to encourage innovation. The present paper presents two ways of exposing this issue, using theoretical sources but also real official data concerning the concept of innovation and also the ways of applying it within small and medium sized enterprises.

  4. Financial Management Challenges In Small And Medium-Sized Enterprises: A Strategic Management Approach

    Directory of Open Access Journals (Sweden)

    Hande Karadag

    2015-02-01

    Full Text Available Abstract :Due to their significant role in creation of new jobs, rise in GDP, entrepreneurship and innovation, small and medium-sized enterprises (SMEs are recognized as the the drivers of socio-economic growth, both in developed and developing economies. In Turkey, 99.9 % of all enterprises fall into SME category. Therefore, the significance of SMEs for Turkish economy and society is much higher in Turkey, compared to other emerging and developed countries. Small and medium-sized companies are faced with a number of challenges whereas the problems arising from “poor financial management” are reported as the major causes of business failures in SMEs. Strategic financial management (SFM which is a research area that has attracted the interest of researchers after 2010, is one of the key managerial areas of SMEs, due to its vital role on the survival, growth and performance of SMEs. The purpose of this paper is to analyze the central role of financial management and identify the financial management challenges and practices that influence the organizational performance in Turkish SMEs, from a strategic management perspective. Within the course of this paper, the importance and challenges of SMEs in Turkey are presented in the first section, while the literature on strategic and financial management in SMEs are reviewed in the second part. In the third section, the recent strategic financial management concept, the implications of strategic financial management practices for SMEs in Turkey and the relationships between strategic financial management practices and SME performance, are discussed. Small and medium sized enterprise finance in Turkey is a developing research area, therefore this paper aims to make a significant contribution to the existing literature by analyzing the major challenges at the conduct of financial management in Turkish SMEs and the influence of strategic financial management practices on the performances of small and

  5. JOB FUNCTION AND GENDER AS DETERMINANTS OF EMPLOYEE REMUNERATION IN THE SMALL AND MEDIUM SIZED ORGNANIZATIONS

    Directory of Open Access Journals (Sweden)

    Frans Maloa

    2015-06-01

    Full Text Available The size and fairness of gaps in employee remuneration are difficult to prove because of the uniqueness of the determinants of employee remuneration in different organisations. The purpose of the research on which this article is based was to review the distribution of employee remuneration across categories of job function and gender in South African small to medium-sized organisations. A purposive sampling method was used and categorical multiple regression analysis was performed. The overall findings of the research suggest that significant distribution of employee remuneration across categories of job function and gender exist in large organisations compared to smaller organisations.

  6. Money and mental wellbeing: a longitudinal study of medium-sized lottery wins.

    Science.gov (United States)

    Gardner, Jonathan; Oswald, Andrew J

    2007-01-01

    One of the famous questions in social science is whether money makes people happy. We offer new evidence by using longitudinal data on a random sample of Britons who receive medium-sized lottery wins of between 1000 pounds and 120,000 pounds (that is, up to approximately US$ 200,000). When compared to two control groups -- one with no wins and the other with small wins -- these individuals go on eventually to exhibit significantly better psychological health. Two years after a lottery win, the average measured improvement in mental wellbeing is 1.4 GHQ points.

  7. Money and mental wellbeing : a longitudinal study of medium-sized lottery wins

    OpenAIRE

    Gardner, Jonathan; Oswald, Andrew J.

    2006-01-01

    One of the famous questions in social science is whether money makes people happy. We offer new evidence by using longitudinal data on a random sample of Britons who receive medium-sized lottery wins of between £1000 and £120,000 (that is, up to approximately U.S. $200,000). When compared to two control groups — one with no wins and the other with small wins — these individuals go on eventually to exhibit significantly better psychological health. Two years after a lottery win, th...

  8. Alibaba.com sourcing guide for Finnish small and medium-sized enterprises

    OpenAIRE

    Lundell, Laura

    2017-01-01

    The objective of this project-based thesis is to offer guidance for Finnish small and medium-sized enterprises (SMEs) about the use of Alibaba.com online marketplace in China-based sourcing, in the form of a guide. The guide offers information about looking for suppliers and products, how to distinguish between sellers and how to contact them, what the recommended sourcing process is and what risks may be involved. In addition, the guide aims to offer a better understanding of Alibaba Group a...

  9. Why Do Small and Medium-Size Freemium Game Developers Use Game Analytics?

    OpenAIRE

    Koskenvoima, Antti; Mäntymäki, Matti

    2015-01-01

    Part 4: E-Business, E-Services and E-Society; International audience; The increased use of the freemium business model and the introduction of new tools have made analytics pervasive in the video game industry. The research on game analytics is scant and descriptive. Thus, reasons for employing game analytics are not well understood. In this study, we analyze data collected with a set of in-depth interviews from small and medium-sized freemium game developers. The results show that game analy...

  10. Strategic management in micro, small and medium-sized businesses in relation to financial success of the enterprise

    Directory of Open Access Journals (Sweden)

    Monika Švárová

    2013-01-01

    Full Text Available Small and medium sized enterprises play an essential role in the economy of the Czech Republic as a report of development of small and medium-sized enterprises and its support from 2010 announces. They are the source of development of towns, regions and the state itself. Small and medium-sized enterprises represent 99.84 % of the whole business subjects. Statistic data underline this position- they indicate that small and medium-sized enterprises employ 2/3 employees. Therefore, occupying small and medium-sized enterprises are to be taken as priority.Strategic management on the level of small and medium-sized enterprises is, as number of authors write, diverse. Small enterprises including micro have less access to capital, they have no money for employing specialists in the field, and they solve administration primarily. The aim of this follow-up GAJU project contribution concerned on process analysis of small and medium-sized enterprises is to summarize the gained results from the view of comparison of the level of strategic management in small and medium-sized enterprises.Nowadays, numbers of enterprises are thinking about whether they are able to remain in the market as an established company, they explore the possibility of improving its position. There is a question for small and medium-sized enterprises management- can strategic management be used as an instrument for increasing competitiveness? The results show that SMEs with a clearly defined strategy show better results of financial health (IN99 and ROA than companies without a defined strategy. In terms of business focus, we were able to demonstrate positive relationship between strategy and finance only for companies in the construction industry, on the significance level of 0.05. Compared to manufacturers and service-providing companies where this relation is not statistically significant.

  11. Can the business model of Handelsbanken be an archetype for small and medium sized banks? A comparative case study

    DEFF Research Database (Denmark)

    Kousgaard Larsen, Morten; Lange Nissen, Jacob; Lueg, Rainer

    2014-01-01

    strengthening of the financial and non-financial position can serve as a blueprint for small- and medium sized banks. We conduct a comparative case study by interviewing Handelsbanken and the disguised ‘Danish Local Bank’ (DLB), where the DLB is a representative example of a small- and medium sized Danish bank...... advantages of ‘The Handelsbanken Way’, this study suggests that the financially troubled small- and medium sized banks in Denmark will not necessarily benefit from the tactical choice of decentralization unless they incorporate specific adjustments. This study contribute to the existing theory concerning...

  12. Barriers to development of the innovation potential in the small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Jakub Tabas

    2011-01-01

    Full Text Available It is a common fact, that innovations are the necessary prerequisite of economic development. With regard to the gradual globalization of the world economy, it is obvious that the strategic objectives of every country are directed to own economic wealth which is lead especially by the small and medium-sized enterprises. Due to the fact that these business entities are creating the most of economic growth of every country, the necessity of research, support and development of their innovation potential is obvious. The last and also the least that one could starve for is the building up the barriers to innovativeness of domestic companies, and to decrease competitiveness of the country.In the paper, the authors are focused on the determination of barriers to innovation potential of small and medium-sized enterprises. For this reason, the secondary research of recent studies on innovation barriers has been elaborated. Subsequently, the primary research has been realized on the statistical sample of 173 SMEs. Based on the data analyses, the authors have proved four statistical interactions between innovation potential and factors which stand as barriers to innovation potential development. This paper is based on the confrontation of outcomes of primary research with the secondary research on world-wide perceived barriers to innovations. Data obtained from the primary research had mostly the qualitative and categorical character. Due to this fact, especially Chi-square Test, normalized Pearson coefficient of contingence and Chuprov’s coefficient have been applied.

  13. APLIKASI MOBILE-CUSTOMER RELATIONSHIP MANAGEMENT UNTUK SMALL AND MEDIUM SIZE ENTERPRISES (SMEs

    Directory of Open Access Journals (Sweden)

    Utaminingsih Linarti

    2015-07-01

    Full Text Available The key factor of enterprise in order to still growth and developed is customer. The customer will give the value to the enterprise in the form of profit. Therefore, enterprises must be able to establish an sustainable relationship to customer. Since 1990 began to develop what is called Customer Relationship Management (CRM. CRM implements between the development of information technology and customer-centric views. The development of technology and the human need's to move quickly, CRM evolved into a mobile CRM. The Internet make mobile-CRM easily used to all of enterprise, especially small and medium size enterprise. This article is aim to explain the role and the applicability of mobile CRM to business level conditions of small and medium size enterprises (SMEs. The presence of mobile phone operating system that is flexible (android system, the internet cost of affordable and the social media applications as analogy of user interface in making mobile CRM application. CRM mobile application can be downloaded or installed through the app store with ease. It encourages mobile-CRM benefit's rather than as a function of customer data collection but became a window for customer information. In addition, the database can be analysis and relate to customer activity. Mobile CRM applications can take advantage of cross selling methods.

  14. Healthy lifestyle behavior of employees in small and medium-sized enterprises in Aydin, Turkey.

    Science.gov (United States)

    Ozvurmaz, Safiye; Mandiracioglu, Aliye

    2017-01-01

    To determine healthy lifestyle behavior and affecting risk factors in workers at small and medium-sized enterprises from four different sectors in Aydin, Turkey. This cross-sectional study was conducted at four different small and medium-sized enterprises in Aydin, Turkey and 264 employees participated in the study. A questionnaire was used for data collection. It consisted of questions about socio-demographic features (age, gender, marital status, education, perceived income, occupation and having children), health status, and medical history, medication use, having occupational accidents and occupational health and safety. Healthy Lifestyle Behavior Scale, which was developed by Walker et al. in 1996, was used to evaluate healthy lifestyle behaviors of the workers. The mean score for Healthy Lifestyle Behavior Scale was 135.46±22.49. Gender, marital status, perceived income, sector of workplace, title, presence of a chronic disease, finding oneself healthy in the previous year and having an occupational accident in the previous year did not significantly affect any subscales of Healthy Lifestyle Behavior Scale. The workers aged over 50 years had significantly higher scores for health responsibility than those aged 20-29 years (pHealthy Lifestyle Behavior Scale and its subscales health responsibility, physical activity, nutrition and spiritual development than those living in a city (phealthy lifestyle and that workers benefiting from occupational health and safety services can display healthy lifestyle behavior.

  15. Simplified product value measurement framework for small and medium sized enterprises

    Directory of Open Access Journals (Sweden)

    S Parkash

    2013-09-01

    Full Text Available Background: The emergences of global markets have increased competition worldwide. For Small Medium Sized Enterprises with limited resources to sustain in what is already a very competitive market there is a need for strong and continuously increasing Product Value to reduce business risks and revenue losses and to increase market share and customer satisfaction. To fulfill this need, Product Value Measurement is necessary to characterize the current status and further improvement. It is not easy to obtain the measures about the Product Value because its many features have qualitative characteristics. We need simplified but result oriented systematic framework to measure it while considering the measurement purpose and how to measure and why do it. Methods: How to design this is the main aim of this research paper. In this paper, GQM (Goal-Question-Metric method as a measurement framework is introduced to measure the Product Value for Small Medium Sized Enterprises along with case study to represent that this framework was effective. Results and conclusions: The proposed Model was effective for focusing on the essence of measurement and for avoiding extra excessive data not necessary for doing the effective measurement.

  16. THE CONCEPT OF TRANSFORMATION OF THE NATIONAL INSTITUTIONAL ENVIRONMENT OF SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Tetiana Stroiko

    2016-11-01

    Full Text Available The aim of the article is an attempt to ground the concept of transformation of national institutional environment as the prerequisites for forming of prosperous class of small and medium-sized enterprises. Institutional analysis considers the interaction on the level of individuals and divides a market transaction into transactions (institutional agreements, estimating their value with the help of transaction costs. We conducted a systematization of the notion that brings the institutional environment to the aggregate of norms, regulations, agreements, rules of the game. For the quality assessment of institutional environment on the macrolevel, direct indicators of its assessment were used – quality indexes in international ratings and activities of specialized institutional researches. Practical significance. In the result the quality of the institutional environment of the assessment of The Global Competitiveness Index is extremely low and needs a systematic increase. Values of indicators of a pillar “Institutions” of The Global Competitiveness Index should be a guiding line for development and introduction of state economic policy. An important line of investigations of development mechanism’s improvement and regulatory policy’s conducting is the institutional environment conception that combines the notions of institute, institutional agreements and transaction costs. A model of institutional environment allows determining of the regulatory policy as a policy that changes elements of institutional environment – institutions, displays in changes of transaction costs. It is grounded that a state apparatus consciously sets as an object the increase of socio-economic role of the entrepreneurship through the creating of favourable conditions of its functioning; a way of this object’s achievement is the regulatory policy, efficiency criterion of which is the improving of national institutional environment’s quality that is

  17. Exploring the Effects of Macro-Environment on the Predisposition to Adopt Strategic Orientation among Small Medium Size Hotel Entrepreneurs

    National Research Council Canada - National Science Library

    Azilah Kasim; Hisham Dzakiria

    2016-01-01

      This paper looks at the effect of macro-environment context on small and medium size hotels' predisposition to adopt strategic orientation using a qualitative approach in its research methodology...

  18. The Relationship of Board Composition to Company Performance in Small and Medium Sized Family Firms: A Theoretical Model

    National Research Council Canada - National Science Library

    Jerry Kudlats; William McDowell

    2015-01-01

    .... This research examines the literature on board composition and strategic decision making, and presents a theoretical model for board composition and firm performance in small and medium sized family firms...

  19. Adoption of the International Accounting Standard by Small and Medium-Sized Entities and its Effects on Credit Granting

    National Research Council Canada - National Science Library

    Enrico Dalla Riva; Bruno Meirelles Salotti

    2015-01-01

    This research examines the relationship between the adoption of the international accounting standard by small and medium-sized entities in Brazil and the cost of credit granted by financial institutions...

  20. Lightweight Medium-Sized Parts Made of Foamed HDPE Processed via Extrusion Blow Moulding: Analysis of Parison Formation

    Directory of Open Access Journals (Sweden)

    Victor Peinado

    2015-02-01

    Full Text Available The manufacturing of medium-sized hollow parts using a foamed high density polyethylene was studied using a conventional accumulator blow extrusion machine and a systematic capture of pictures during the parison formation. To fully monitor the parison formation, several experiments were carried out varying the chemical foaming agent content from 0 wt.% to 2 wt.% and increasing the push extrusion speed. Results pointed out greater wall thickness, diameter, and length of parisons with higher weight percentage of blowing agent and extrusion speed. A full experimental characterisation of parison dimensions was essential to assure a proper prediction of the blowing step. Information was used as input for modelling and simulations of the blowing phase of an industrial container. To validate the proposed methodology, a blow moulding process of a generic container was simulated using Ansys Polyflow v13 software and its finite element analysis which provided an accurate approximation of the wall thickness expected. Further real tests on the simulated container also demonstrated that, in those parisons with a 1 wt.% CFA concentration and higher blowing pressure, there was remarkable improvement on their packaging properties such as decreasing of the total weight of the container and an enhancement of its surface quality.

  1. Knowledge management in small and medium-sized companies; Wissensmanagement bei kleinen und mittleren Unternehmen

    Energy Technology Data Exchange (ETDEWEB)

    Basu, M. [Netzwirtschaft, EWR Netz GmbH, Worms (Germany); Neises, C. [Regulierungsmanagement, regionetz GmbH, Dueren (Germany)

    2008-12-15

    Knowledge management has now also reached the energy economy, as first branch-specific seminars show. This awakening interest is very much to be welcomed, although until now it has been more the representatives of large energy companies who have made themselves heard. Public utilities, which as a rule are subsumed under the category ''small and medium sized company'', have other possibilities as well as limitations than large corporations when it comes to knowledge management. The present article explains what knowledge management is and how public utilities and regional supply companies can identify and make practical use of opportunities available to them through knowledge management while giving due consideration to their structural characteristics.

  2. Software-Defined Solutions for Managing Energy Use in Small to Medium Sized Commercial Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Peffer, Therese [Univ. of California, Berkeley, CA (United States); Council on International Education Exchange (CIEE), Portland, ME (United States); Blumstein, Carl [Council on International Education Exchange (CIEE), Portland, ME (United States); Culler, David [Univ. of California, Berkeley, CA (United States). Electrical Engineering and Computer Sciences (EECS); Modera, Mark [Univ. of California, Davis, CA (United States). Western Cooling Efficiency Center (WCEC); Meier, Alan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-09-10

    The Project uses state-of-the-art computer science to extend the benefits of Building Automation Systems (BAS) typically found in large buildings (>100,000 square foot) to medium-sized commercial buildings (<50,000 sq ft). The BAS developed in this project, termed OpenBAS, uses an open-source and open software architecture platform, user interface, and plug-and-play control devices to facilitate adoption of energy efficiency strategies in the commercial building sector throughout the United States. At the heart of this “turn key” BAS is the platform with three types of controllers—thermostat, lighting controller, and general controller—that are easily “discovered” by the platform in a plug-and-play fashion. The user interface showcases the platform and provides the control system set-up, system status display and means of automatically mapping the control points in the system.

  3. The Internationalization Process of Mature Danish Small and Medium-Sized Enterprises

    DEFF Research Database (Denmark)

    Myhre, Malene

    Small and medium-sized enterprises (SMEs) are important to growth, economic development, and job creation in many nations, and especially in small countries like Denmark. According to Statistics Denmark, there are roughly 300,000 active companies in Denmark. Of these, 99.4% are classified as SMEs....... International trade is important for small countries, where the economy as a rule is closely integrated (both economically and financially) with the rest of the world. Despite the recognized importance, there is little knowledge about how SMEs approach internationalization. In particularly we lack studies...... of what makes mature enterprises which have predominantly had a domestic orientation decide to internationalize. Through ten case studies in three industries – machinery manufacturing, food distribution, and healthcare – this study qualitatively explores the internationalization process of mature SMEs...

  4. Corporate Environmental Initiatives in Small and Medium Sized Enterprises and Their Outcome

    DEFF Research Database (Denmark)

    Madsen, Henning; Ulhøi, John Parm

    2016-01-01

    The impact from corporate business activities on the natural environment and society at large has been in focus for quite some time. The focus has often been on corporate environmental sustainability initiatives reflecting industry’s response to concerns expressed by key stakeholders as well...... surveys of industrial companies in Denmark over a number of years. The results indicate a slightly increasing involvement over time, but also that the level of results achieved is lower than the level of initiatives taken. That is, the reactive attitude reported previously still seems to be prevailing....... The results also seem to indicate that the size of the company may have a negative influence in some situations, since smaller companies seems to be better at achieving results compared with medium sized companies....

  5. Toward the construction of a medium size prototype Schwarzschild-Couder telescope for CTA

    Science.gov (United States)

    Rousselle, J.; Byrum, K.; Cameron, R.; Connaughton, V.; Errando, M.; Griffiths, S.; Guarino, V.; Humensky, T. B.; Jenke, P.; Kaaret, P.; Kieda, D.; Limon, M.; Mognet, I.; Mukherjee, R.; Nieto, D.; Okumura, A.; Peck, A.; Petrashyk, A.; Ribeiro, D.; Stevenson, B.; Vassiliev, V.; Yu, P.

    2015-09-01

    The construction of a prototype Schwarzschild-Couder telescope (pSCT) started in early June 2015 at the Fred Lawrence Whipple Observatory in Southern Arizona, as a candidate medium-sized telescope for the Cherenkov Telescope Array (CTA). Compared to current Davies-Cotton telescopes, this novel instrument with an aplanatic two-mirror optical system will offer a wider field-of-view and improved angular resolution. In addition, the reduced plate scale of the camera allows the use of highly-integrated photon detectors such as silicon photo multipliers. As part of CTA, this design has the potential to greatly improve the performance of the next generation ground-based observatory for very high-energy (E>60 GeV) gamma-ray astronomy. In this contribution we present the design and performance of both optical and alignment systems of the pSCT.

  6. FINANCING OF FIXED ASSET INVESTMENT IN THE SMALL AND MEDIUM-SIZED ENTERPRISES IN POLAND

    Directory of Open Access Journals (Sweden)

    Beata Geruzel-Dudzińska

    2016-03-01

    Full Text Available Small and medium-sized enterprises play an important role in the economy, creates, because a significant part of GDP, provides employment to many millions of people. One of the main barriers to the development of these enterprises, not only in Poland but also in EU countries, is the scarcity of equity and the difficulty in obtaining external sources of financing. It is not just about lack of funds to finance current operations, but also, and perhaps above all, lack of investment in fixed assets. This paper aims to present available sources of financing of fixed assets for enterprises from the SME sector and the assessment of their use by these companies.

  7. The ABC-paradox: is Time Driven ABC relevant for small and Medium sized enterprises (SME)?

    DEFF Research Database (Denmark)

    Fladkjær, Henrik Find; Jensen, Erling

    -books and in curriculum at most business schools. But ABC is not used very much by the compa-nies. Especially in small and medium enterprises ABC is rarely implemented. This is primarily due to two things: First, the ABC model is too difficult to implement. Second, the data foundation for the model is not available...... in the required quality in the ERP systems used by the businesses. In this article we will explore ways of overcoming these two related problems. We will explore these issues particularly in relation to small and medium enterprises. Through a theoretical analysis and practical implementation in a medium sized...... solutions that can be used in small and medium enter-prises....

  8. Branding and outcomes in small and medium-sized enterprises (SMEs)

    DEFF Research Database (Denmark)

    Odoom, Raphael; Narteh, Bedman; Rand, John

    2017-01-01

    were drawn from 304 small and medium-sized enterprises (SMEs) in Ghana. The hypothesized relationships were analyzed using Structural Equation Modeling. The study found that resources and capabilities possessions might not be enough to produce the optimum branding benefits for enterprises. A better...... result, however, emerges when these resources and capabilities are integrated with well-coordinated branding efforts of the enterprises. The study offers several implications for managers of small businesses based on the findings of the study.......The study investigates the relationships of enterprise resources and branding capabilities with branding efforts and branding benefits. It examines the differential effect of physical resources and branding capabilities on enterprises’ branding efforts and outcomes. Empirical data for the study...

  9. Adoption of an information systems security policy in small and medium sized enterprises.

    Directory of Open Access Journals (Sweden)

    Isabel Maria Lopes

    2017-03-01

    Full Text Available Information Systems Security (ISS is a relevant fact for current organizations. This paper focuses on Small and Medium Sized Enterprises (SMEs. This article aims to constitute an empirical study on the applicability of the Action Research (AR method in information systems, more specifically by assessing the adoption of an ISS policy in six SMEs, and identifying the critical success factors in adopting an ISS policy. The research question we intend to answer is to what extent this research method is adequate to reach the proposed goal. The results of the study suggest that AR is a promising means for the evaluation of ISS policies adoption. It can both act as a research method that improves the understanding about the reasons why the policy has been abandoned, and as a change method, assisting practitioners to overcome barriers and suggesting measures to be implemented.

  10. Towards „intelligent” financial analysis in the management of small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Bartłomiej Nita

    2015-12-01

    Full Text Available The aim of the paper is to present the possibilities of extending the „intelligence” of financial analysissystems designed for managers of small and medium-sized enterprises (SMEs. The paper first presentsthe question of obtaining analytical information which is essential for supporting managerial decisions,particularly with regard to SMEs. Next, the nature and use of ontologies as well as eye-tracking in modelingmanagerial knowledge in respect of financial analysis are discussed. In the last section the authorsdepict a research experiment that was conducted using eye-tracking, focusing on technical terms, contentand knowledge that can be obtained thanks to this study. In the research experimental methodology wasapplied based on actual financial data, using the Bilander’s BINOCLE and eye-tracking software TobiiStudioTM by Tobii.

  11. Selecting Sustainability Indicators for Small to Medium Sized Urban Water Systems Using Fuzzy-ELECTRE.

    Science.gov (United States)

    Chhipi-Shrestha, Gyan; Hewage, Kasun; Sadiq, Rehan

    2017-03-01

      Urban water systems (UWSs) are challenged by the sustainability perspective. Certain limitations of the sustainability of centralized UWSs and decentralized household level wastewater treatments can be overcome by managing UWSs at an intermediate scale, referred to as small to medium sized UWSs (SMUWSs). SMUWSs are different from large UWSs, mainly in terms of smaller infrastructure, data limitation, smaller service area, and institutional limitations. Moreover, sustainability assessment systems to evaluate the sustainability of an entire UWS are very limited and confined only to large UWSs. This research addressed the gap and has developed a set of 38 applied sustainability performance indicators (SPIs) by using fuzzy-Elimination and Choice Translating Reality (ELECTRE) I outranking method to assess the sustainability of SMUWSs. The developed set of SPIs can be applied to existing and new SMUWSs and also provides a flexibility to include additional SPIs in the future based on the same selection criteria.

  12. Networked Virtual Organizations: A Chance for Small and Medium Sized Enterprises on Global Markets

    Science.gov (United States)

    Cellary, Wojciech

    Networked Virtual Organizations (NVOs) are a right answer to challenges of globalized, diversified, and dynamic contemporary economy. NVOs need more than e-trade and outsourcing, namely, they need out-tasking and e-collaboration. To out-task, but retain control on the way a task is performed by an external partner, two integrations are required: (1) integration of computer management systems of enterprises cooperating within an NVO; and (2) integration of cooperating representatives of NVO member enterprises into a virtual team. NVOs provide a particular chance to Small and Medium size Enterprises (SMEs) to find their place on global markets and to play a significant role on them. Requirements for SMEs to be able to successfully join an NVO are analyzed in the paper.

  13. Improved Cost Management at Small and Medium Sized Road Transport Companies: Case Hungary

    Directory of Open Access Journals (Sweden)

    Zoltan Bokor

    2015-10-01

    Full Text Available Small and medium sized road freight transport companies located in Hungary are facing strong competition on the logistics market. An advanced cost management system supporting decisions on capacity allocations or pricing may be a competitive advantage for them and indirectly for the whole economy as well. Still, they generally apply simple, traditional cost calculation regimes, potentially sufficient in case of a homogeneous service portfolio. Nevertheless, road haulage companies with heterogeneous service structures may witness information distortions when using traditional costing methods. So it might be recommended for them to introduce better costing principles. To support an improved transport costing, a multi-level full cost allocation model has been set up and tested in this paper. The research results have pointed out that such a methodological development accompanied by the extension of the data collection mechanism can contribute to making the cost management systems of road freight transport companies more effective.

  14. Supply Chain adoption in Small and Medium-Sized Enterprises (SMEs)

    DEFF Research Database (Denmark)

    Juhl, Mathias Thim; Bernon, Mike

    and customer needs: “outside-in” business approach, with a strong focus on needs and expectations of the customer and competencies to develop the capabilities of the supply chain accordingly. Research Impact: This paper provides a call to academic colleagues to further research the adoption of supply chain......Purpose: The importance of having a competitive supply chain strategy is not to be underestimated (Underwood & Agg 2012; Aronow et al. 2014). Despite the importance of creating strong supply chain capabilities, small and medium-sized enterprises (SMEs) find it difficult to implement supply chain...... management (Vaaland & Heide 2007). The aim of this research was to explore supply chain adoption in SMEs. The research was based upon investigating the extent to which supply chain management is adopted by SMEs, and what factors support companies in achieving consistency between supply chain capabilities...

  15. Adaptive Traffic Control Systems in a medium-sized Scandinavian city

    DEFF Research Database (Denmark)

    Agerholm, Niels; Olesen, Anne Vingaard

    2017-01-01

    Adaptive Traffic Control Systems (ATCS) are aimed at reducing congestion. ATCS adapt to approaching traffic to continuously optimise the traffic flows in question. ATCS have been implemented in many locations, including the Scandinavian countries, with various effects. Due to congestion problems......, ATCS were installed in the eight signalised intersections of a 1.7 km stretch of the ring road in the medium-sized Danish city of Aalborg. To measure the effect of ATCS a with/without study was carried out. GPS data from a car following the traffic, recorded transportation times for buses in service......, and GPS data from a range of cars driving on the ring road formed the basis for the study. The result of ATCS implementation was a significant 17% reduction in transportation time on the ring road in the most congested period, the afternoon peak. Less significant effects were found regarding the morning...

  16. Accelerating Innovation in Small and Medium-Sized Enterprises in the ICT Services Sector

    Directory of Open Access Journals (Sweden)

    Juan Vicente García Manjón

    2016-09-01

    Full Text Available This work is aimed at establishing key organizational strategies that push small and medium-sized enterprises (SMEs in the information and communication technologies (ICT services sector to be more innovative. Following an input and output approach, a theoretical model is built that helps determine such key factors. Then the model is validated with fieldwork carried out on a representative sample in Castile-Leon region (Spain. According to this model, the decision to innovate (and the trigger for research and development [R&D] activities in SMEs in the ICT services sector is the result of needs that are presented by customers (public or private sector in tailored projects. All the same, the factors leading to innovation are in order of importance, the technological level of the company, the effort made by the company in R&D, and finally, systems of incentives.

  17. Current information technology needs of small to medium sized apparel manufacturers and contractors

    Energy Technology Data Exchange (ETDEWEB)

    Wimple, C., LLNL

    1998-04-01

    This report documents recent efforts of the American Textile Partnership (AMTEX{sup TM}) Demand Activated Manufacturing Architecture (DAMA) Project to identify opportunities for cost effective enhanced information technology use by small to medium sized apparel manufacturers and contractors. Background on the AMTEX/DAMA project and objectives for the specific DAMA Small and Medium Enterprise (SME) effort are discussed in this section. The approach used to gather information about current opportunities or needs is outlined in Section 2 Approach, and relevant findings are identified and a brief analysis of the information gathered is presented in Section 3 Findings. Recommendations based on the analysis, are offered in Section 4 Recommendations, and plans are suggested for DAMA follow-on in Section 5 Future Plans. Trip reports for each of the companies visited are contained in Appendix E - Company Trip Reports. These individual reports contain the data upon which the analysis presented in Section 3 Findings is based.

  18. Development of a Simplified Process Integration Methodology for application in Medium-Size Industries

    DEFF Research Database (Denmark)

    Bergamini, Riccardo; Nguyen, Tuong-Van; Bühler, Fabian

    2016-01-01

    Achieving significant energy savings is fundamental for reaching the ambitious EU 20-20-20 environmental targets. Several methodologies based on the Pinch concept have proved to be highly effective for identifying and assessing energy savings possibilities in the industrial sector. However, saving...... opportunities may be missed in the case of medium-size industries. Applying these methods may indeed be costly and time consuming,as it can require large engineering efforts, e.g., for data acquisition.This paper presents a methodology based on process integration techniques, termed "Specific Savings...... or estimates is discussed, since data acquisition is a severely time-consuming task in retrofit projects.This novel methodology is applied to a Danish dairy factory: the results and the method itself are compared with conventional pinch analysis. The findings show that the SSP method is a tool able to simplify...

  19. MACROECONOMIC CLIMATE AND THE SMALL AND MEDIUM SIZE COMPANIES IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Andrei Rădulescu

    2017-10-01

    Full Text Available Small and medium size companies (SMEs represent the engine of the economy in the member states of the European Union. In Romania, SMEs entered the post-crisis cycle in 2013 after a severe adjustment process under the impact of the Great Recession. The economic performance of SMEs is strongly influenced by the macroeconomic climate. The important role of SMEs in the economy has determined the Romanian government to implement several measures in order to support their activity.The present paper highlights the mid-term macroeconomic outlook for Romania, as well as the recent developments related to SMEs, along with the main measures implemented by the Government over the past years in order to support the development of these companies.

  20. Small and medium-sized enterprises in terms of their goals

    Directory of Open Access Journals (Sweden)

    Březinovă Monika

    2014-01-01

    Full Text Available The strategic management represents current direction of management. It is applied in all types of enterprises, including small and medium sized ones. Using principles of process management within SMEs has its limitations caused mainly by the size of the enterprise and the related focus on operational management. Other specificities are function accumulation, informal leadership, preference for oral communication before written, etc. Nevertheless, implementation of strategic management can increase competitiveness, reduce costs, improve decision-making, facilitate implementation of the employee motivation system, shorten delivery times, higher quality of customer satisfaction, etc. The aim of this article is to find out how much SME includes principals of the strategic management as their aim.

  1. Competitive intelligence tools used by small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Tshilidzi Eric Nenzhelele

    2015-08-01

    Full Text Available Small and Medium-sized Enterprises (SMEs contribute highly to the gross domestic product, reduction in unemployment, wealth creation and improvement in the quality of life. Due to technology and globalisation, SMEs now compete with enterprises beyond the borders of their country. To survive in this global competitive business environment, SMEs seek for tools that offer competitive advantage. Competitive Intelligence (CI provides competitive advantage to enterprises that practice it. While CI practice has been widely research for larger enterprises, there is lack of research on CI practice pertaining to SMEs. This research establishes tools used by SMEs in CI practice. The research was quantitative in nature and a self-administered questionnaire was used to collected data from owners/managers of SMEs

  2. Decision-makers' Risk Perception in the Internationalisation of Small and Medium-Sized Firms

    DEFF Research Database (Denmark)

    Eduardsen, Jonas Strømfeldt; Marinova, Svetla Trifonova

    2016-01-01

    This study examines the risk perception of decision-makers in small and medium sized enterprises (SMEs) and the factors underlying these perceptions in the process of internationalization of their firms. While risk perception has been identified as a potential predictor variable...... in internationalisation research, very little work has been done exploring the factors and processes that shape decision-makers’ perception of risk. A qualitative interview-based approach was adopted by collecting data from thirty-two Danish SMEs operating in four different industries. Findings suggest that while risk...... awareness exists, decision-makers do not perceive internationalisation as risky behaviour. Findings highlight the importance of decision-makers’ background, including cognitive and psychological characteristics, such as self-efficacy and locus of control, and their experiences in explaining risk perceptions...

  3. Larval assemblages of large and medium-sized pelagic species in the Straits of Florida

    Science.gov (United States)

    Richardson, David E.; Llopiz, Joel K.; Guigand, Cedric M.; Cowen, Robert K.

    2010-07-01

    Critical gaps in our understanding of the distributions, interactions, life histories and preferred habitats of large and medium-size pelagic fishes severely constrain the implementation of ecosystem-based, spatially structured fisheries management approaches. In particular, spawning distributions and the environmental characteristics associated with the early life stages are poorly documented. In this study, we consider the diversity, assemblages, and associated habitat of the larvae of large and medium-sized pelagic species collected during 2 years of monthly surveys across the Straits of Florida. In total, 36 taxa and 14,295 individuals were collected, with the highest diversity occurring during the summer and in the western, frontal region of the Florida Current. Only a few species (e.g. Thunnus obesus, T. alalunga, Tetrapturus pfluegeri) considered for this study were absent. Small scombrids (e.g. T. atlanticus, Katsuwonus pelamis, Auxis spp.) and gempylids dominated the catch and were orders of magnitude more abundant than many of the rare species (e.g. Thunnus thynnus,Kajikia albida). Both constrained (CCA) and unconstrained (NMDS) multivariate analyses revealed a number of species groupings including: (1) a summer Florida edge assemblage (e.g. Auxis spp., Euthynnus alleterattus, Istiophorus platypterus); (2) a summer offshore assemblage (e.g. Makaira nigricans, T. atlanticus, Ruvettus pretiosus, Lampris guttatus); (3) an ubiquitous assemblage (e.g. K. pelamis, Coryphaena hippurus, Xiphias gladius); and (4) a spring/winter assemblage that was widely dispersed in space (e.g. trachipterids). The primary environmental factors associated with these assemblages were sea-surface temperature (highest in summer-early fall), day length (highest in early summer), thermocline depth (shallowest on the Florida side) and fluorescence (highest on the Florida side). Overall, the results of this study provide insights into how a remarkable diversity of pelagic species

  4. An Initial Implementation of Multiagent Simulation of Travel Behavior for a Medium-Sized City in China

    Directory of Open Access Journals (Sweden)

    Chengxiang Zhuge

    2014-01-01

    Full Text Available Since the traditional four-step model is so simple that it cannot solve complex modern transportation problems, microsimulation is gradually applied for transportation planning and some researches indicate that it is more compatible and realistic. In this paper, a framework of agent-based simulation of travel behavior is proposed, which is realized by MATSim, a simulation tool developed for large-scale agent-based simulation. MATSim is currently developed and some of its models are under training, so a detailed introduction of simulation structure and preparation of input data will be presented. In practice, the preparation process differs from one to another in different simulation projects because the available data for simulation is various. Thus, a simulation of travel behavior under a condition of limited available survey data will be studied based on MATSim; furthermore, a medium-sized city in China will be taken as an example to check whether agent-based simulation of travel behavior can be successfully applied in China.

  5. Sexual dimorphism of medium-sized neurons with spines in human nucleus accumbens

    Directory of Open Access Journals (Sweden)

    Sazdanović Маја

    2013-01-01

    Full Text Available The nucleus accumbens is a limbic nucleus, representing part of the striatum body, and together with the caudate nucleus and putamen, it lies on the septum. The aim of this study was to examine morphological sexual dimorphism in spine density and also to undertake an immunohistochemical study of expression for estrogen and progesterone receptors in the medium-sized neurons in the nucleus accumbens. The research was conducted on twenty human brains of persons of both sexes, between the age of 20-75 years. The Golgi method was applied to determine the types and subtypes of neurons, morphologies of soma, dendrites and axons, as well as the relations between the cells and glial elements. The following were quantitatively examined: the maximum diameter of the neurons, the minimal diameter of the neurons, and the total length of the dendrites. The expression of receptors for estrogen and progesterone, their distribution and intensity were defined immunohistochemically. The parameters of the bodies of neurons in the shell and core of the nucleus accumbens were studied in both men and women. No statistically significant differences were found. Examination of the spine density showed statistical significance in terms of a higher density of spines in women. Immunohistochemically, in the female brain estrogen expression is diffusely spread in a large number of neurons; it is extra nuclear, of granular appearance and high intensity. In the male brain, expression of estrogen is visible and distributed over about one half of different types of neurons; it is extra nuclear, of granular appearance, mostly of middle and low staining intensity. Expression of progesterone in the female brain was very discreet and on a very small number of neurons; it was extra nuclear and with a weak staining intensity. Expression of progesterone in the male brain was distributed on a small number of neurons. It had a granular appearance, it was extra nuclear, with a very low

  6. A framework for effective implementation of lean production in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Amine Belhadi

    2016-09-01

    Full Text Available Purpose: The present paper aims at developing an effective framework including all the components necessary for implementing lean production properly in Small and Medium-sized Enterprises. Design/methodology/approach: The paper begins with the review of the main existing framework of lean implementation in order to highlight shortcomings in the literature through a lack of suitable framework for small companies. To overcome this literature gap, data of successful initiatives of lean implementation were collected based on a multiple case study approach. These initiatives has been juxtaposed in order to develop a new, practical and effective framework that includes all the components (process, tools, success factors that are necessary to implement lean in Small and Medium-sized Enterprises. Findings: The proposed framework presents many significant contributions: First, it provides an overcoming for the limitations of the existing frameworks by proposing for consultants, researchers and organizations an effective framework for lean implementation in SMEs that allows SMEs to benefit from competitive advantages  gained by lean. Second, it brings together a set of the more essential and critical elements of lean implementation commonly used by SMEs and derived from the practical experiences of them in lean implementation. Finally, it highlights the successful experiences of small companies in implementing lean programs and then proves that lean can give a relevant results even for SMEs. Research limitations/implications: The proposed framework presents a number of limitations and still evokes extension for further researches: Although it was derived from practical experiences of SMEs, the proposed framework is not supported by practical implementation. On the other hand and even though the elements in the proposed framework from the practical experiences of four SMEs, the identified elements need to be generalized and enriching by conducting

  7. Modern methods of evaluation existing suppliers and suppliers selected by customer for small and medium-sized companies

    Directory of Open Access Journals (Sweden)

    Marie Jurová

    2010-01-01

    Full Text Available On existing conditions on global market (almost identical quality, almost identical purchasing values companies have to definite the total rating of importance of evaluative criteria. In post-crisis period the problem of suppliers’ evaluation is one of the biggest, because companies had to use all resources and all possibilities to develop their own business. Many authors wrote about collaborative planning and warehousing as one of possibilities to optimization work inside supply chain. For this paper define small and medium-sized enterprises (SME as enterprises with the size of maximum 250 em­ployers. In literature was read we couldn’t find information about own system of suppliers evaluation for small and medium-sized enterprises. SME can have some different types of business and in this case need the universal system of eva­lua­tion. The research of this paper is oriented on small and medium-sized enterprises with different types of business. The new theoretical universal method of calculation for evaluation existing suppliers for small and medium-sized enterprises will present in this paper. This theoretical method is based on average values. This method includes traditional evaluative criteria (quality, delivery time and other (mobility of supplier, possibilities of new level of partnership. This method of evaluation can not be used for continual manufacture. New method can improve the total evaluation of supplier in small and medium-sized enterprises.

  8. Complex Chemical Reaction Networks from Heuristics-Aided Quantum Chemistry.

    Science.gov (United States)

    Rappoport, Dmitrij; Galvin, Cooper J; Zubarev, Dmitry Yu; Aspuru-Guzik, Alán

    2014-03-11

    While structures and reactivities of many small molecules can be computed efficiently and accurately using quantum chemical methods, heuristic approaches remain essential for modeling complex structures and large-scale chemical systems. Here, we present a heuristics-aided quantum chemical methodology applicable to complex chemical reaction networks such as those arising in cell metabolism and prebiotic chemistry. Chemical heuristics offer an expedient way of traversing high-dimensional reactive potential energy surfaces and are combined here with quantum chemical structure optimizations, which yield the structures and energies of the reaction intermediates and products. Application of heuristics-aided quantum chemical methodology to the formose reaction reproduces the experimentally observed reaction products, major reaction pathways, and autocatalytic cycles.

  9. PROSPECTS OF DEVELOPMENT OF SMALL AND MEDIUM-SIZED ENTERPRISES IN UKRAINIAN AGRICULTURE

    Directory of Open Access Journals (Sweden)

    O. Pimenova

    2016-06-01

    Full Text Available Main directions of development of small and medium-sized enterprises in Ukrainian agriculture are examined. It is determined that entrepreneurship in agrarian sector is a driving force behind the development of agriculture, as these activities contributes to the production of quality agricultural products that satisfies the needs of society, food security, independence and improves the living standards of rural population. Potential customers of small parties of harvest in Ukrainian grain market are analyzed. The ways of mutually beneficial cooperation between Ukrainian farmers and entrepreneurs are proved. The study of foreign experience has proven that strengthening the competitiveness of Ukrainian agricultural products in the context of globalization is possible on the basis of mutually beneficial cooperation of Ukrainian farmers and entrepreneurs, where recent purchase of output at market prices for the purpose of resale or creation of agricultural cooperatives, such form of economy in agrarian relations that combines a balanced economic, social and environmental components. In particular in paper is shown that sustainable economic management provide only forms of economy that take into account the socioeconomic and geophysical specifics of agriculture, particularities of agricultural labor and methods of management. The most common among these forms are farmers.

  10. IMPORTANCE OF SMALL AND MEDIUM-SIZED ENTERPRISES IN ROMANIAN ECONOMY

    Directory of Open Access Journals (Sweden)

    BĂLĂNESCU MĂDĂLINA

    2013-08-01

    Full Text Available The market economy has reduced the number of large enterprises and has determinated the emergence ofa special class like small and medium-sized enterprises. Those companies play a special role in the nationaleconomy, especially through the fact that attract about 65% of employees in Romania, makes significantinvestments, takes approximately 30% of gross value added in the national economy, operates mainly in servicesactivity, are flexible, concerned with development and have the ability to adopt new technologies. The SMEsector has been affected by the crisis, but not in the same measure as large enterprises. This fact is demonstratedby the economic and financial indicators that I have analised, in 2011 SME beeing able to overcome the crisisand to achieve higher performance than in the years before crisis. The SME sector is considered the most activesector of the modern economy, plays a important role in the economic structure of our country, helping to ensureeconomic and social development as it is shown by the strong bond that exist between the GVA in SME sectorand total GVA added to the national economy, demonstrated in the calculations that I have made in this study.

  11. Quantitative evaluation of waste prevention on the level of small and medium sized enterprises (SMEs).

    Science.gov (United States)

    Laner, David; Rechberger, Helmut

    2009-02-01

    Waste prevention is a principle means of achieving the goals of waste management and a key element for developing sustainable economies. Small and medium sized enterprises (SMEs) contribute substantially to environmental degradation, often not even being aware of their environmental effects. Therefore, several initiatives have been launched in Austria aimed at supporting waste prevention measures on the level of SMEs. To promote the most efficient projects, they have to be evaluated with respect to their contribution to the goals of waste management. It is the aim of this paper to develop a methodology for evaluating waste prevention measures in SMEs based on their goal orientation. At first, conceptual problems of defining and delineating waste prevention activities are briefly discussed. Then an approach to evaluate waste prevention activities with respect to their environmental performance is presented and benchmarks which allow for an efficient use of the available funds are developed. Finally the evaluation method is applied to a number of former projects and the calculated results are analysed with respect to shortcomings and limitations of the model. It is found that the developed methodology can provide a tool for a more objective and comprehensible evaluation of waste prevention measures.

  12. Experimental testing of centrifugal pump: small and medium sized enterprise product

    Science.gov (United States)

    Ismail, R.; Paddiyatu, F.; Khafidh, M.; Nugroho, S.; Sugiyanto, S.; Jamari, J.

    2014-06-01

    This paper reports the experimental testing for centrifugal pump for fisherman ship, manufactured by small and medium sized enterprises in Central Java Province, Indonesia. The research covers material analysis, component observation, endurance and vibration test. Six centrifugal pumps are tested and three main pump components are discussed: shaft, bearings and seals. The results show that the material of the shaft is predicted to support and transmit the load from the engine to impeller. The problem found in the tolerance and geometry accuracy of the shaft which causes difficulties during assembling process, excessive wear and leakage during testing. From the endurance and vibration test, the ball bearings fail and lock the shaft due to the fatigue on the rolling elements and raceways. The oil seal and water seal also fail in maintaining the oil and water in the chamber and induce the unlubricated system for the ball bearings. Some suggestions are delivered to improve the product quality of the centrifugal pump. A good quality of the centrifugal pump for fishermen ship and long life span is expected to be produced by local SMEs to win the free trade competition in the Indonesian market.

  13. Business Benefits from Enterprise Systems Implementation in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Sanjay Mathrani

    2009-08-01

    Full Text Available The market for enterprise systems (ESs continues to grow as business becomes increasingly global and competitive. Increasingly, the market focus for ES vendors is on small businesses. The purpose of this study is to provide a unique ES vendor/consultant perspective on (a the business benefits small and medium-sized enterprises (SMEs expect from their ES investment and (b to examine current practices of ES implementation in SMEs through a conceptual framework that considers the organisational, process and strategic context of the implementation. This study does so with interview data collected from ES vendors, ES consultants and IT research firms, who are the key players in the New Zealand ES industry. A distinctive contribution of this research is the vendor/consultant perspective as the unit of analysis, rather than the SME perspective commonly used in similar research. The vendor/consultant perspective offers a comprehensive viewpoint that extends across numerous SMEs in a variety of industries. Findings from interviews with these professionals indicate that although many ES implementations are several years old now, SMEs have only recently started tracking benefits through analytical processes in expectation to realise business value from their ES investment. The results also identify how ES implementation practices are adapting to be more suitable to the SME sector, an important market for ES vendors given the saturation of the large enterprise market for ES implementation.

  14. Role of Relationship Marketing in Small and Medium-Sized Entreprises

    Directory of Open Access Journals (Sweden)

    Ružica Butigan

    2011-06-01

    Full Text Available Along with marketing, small and medium enterprises (SMEs are commonly associated in literature with relationship marketing which results in marketing networks. This paper examines the specific characteristics that differentiate large companies from small and medium-sized enterprises, and the reasons that prevent SMEs from engaging in traditional marketing within the scope of marketing mix. The paper also shows that the key characteristic which distinguishes small from large companies is a prominent role of owner/managers. The owner/manager affects marketing of SMEs by creating his or her own personal networks with stakeholders in the environment, and considers it an important strategic focus and a factor that increases the performance of marketing decision-making. After a thorough review of secondary data sources this paper examines relationship marketing as a marketing framework for SMEs and, finally, proves that relationship marketing is more appropriate for SMEs than are traditional marketing concepts, that relationship marketing and network marketing create an important framework for SMEs and that there is a link between relationship marketing, personal networks and SMEs.

  15. Correlates of Tax Compliance of Small and Medium Size Businesses in Cameroon

    Directory of Open Access Journals (Sweden)

    Oludele Akinloye Akinboade

    2015-12-01

    Full Text Available Taxation provides a predictable and stable flow of revenue to finance development objectives. This is important in a country like Cameroon that has serious challenges with meeting its development objectives. Small and medium enterprises (SMEs are significant for economic growth in the country, contributing as much as about 22 percent of the gross domestic product. SMEs generate taxable incomes. They also collect employment and value added taxes on behalf of the government. Taxation, however, imposes high cost to small businesses. SMEs are less tax compliant in comparison to large businesses. SMEs are considered the ‘hard to tax group from the informal sector.’ As such, the literature suggests that only a fraction of their taxable incomes is reported to tax authorities. Against this background, factors that correlate with tax compliance of 575 small and medium size companies in Cameroon are discussed from a survey of companies in the manufacturing and wholesale sectors. High registration cost and time-consuming processes promote tax non-compliance. The perception that tax system is corrupt discourages registration and filing compliance. When there are too many compliance hurdles, the probability of filing compliance is reduced. However, a fair and static system encourages filing and registration compliance. A clear and consistent tax system promotes filing compliance. Authorities that understand their responsibilities and are willing to respond to enquiries during the registration process promote tax compliance in general.

  16. Strategies for Successful Information Technology Adoption in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Morteza Ghobakhloo

    2012-02-01

    Full Text Available Information Technology (IT adoption is an important field of study in a number of areas, which include small and medium-sized enterprises (SMEs. Due to the numerous advantages of IT, SMEs are trying to adopt IT applications to support their businesses. IT adoption by SMEs differs from larger organizations because of their specific characteristics, such as resources constraints. Therefore, this research aims to provide a better and clearer understanding of IT adoption within SMEs by reviewing and analyzing current IT literature. In this research, the review of literature includes theories, perspectives, empirical research and case studies related to IT adoption, in particular within SMEs from various databases such as Business Premier, Science Direct, JStor, Emerald Insight and Springer Link. The proposed model of effective IT adoption is believed to provide managers, vendors, consultants and governments with a practical synopsis of the IT adoption process in SMEs, which will in turn assist them to be successful with IT institutionalization within these businesses.

  17. Operational Risk Assessment and Management in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Viktorija Stasytytė

    2015-07-01

    Full Text Available Modern organizations have raised a need to actively and quickly react to the changes in external business environment, as well as in internal processes considering not only the present situation, but also evaluating possible changes and forecasting the future. Enterprise risk assessment and management, which is strongly related with foreseeing the uncertain future, becomes topical not only scientifically, but also practically seeking to reveal new and unique solutions. Operational risk management in small and medium enterprises, creating the largest part of value added in the whole European Union, demands a separate attention and coordinated decisions and means. The objective of the paper – to analyse the process of enterprise risk management in small and medium-sized enterprises, as well as to propose adequate risk management solutions for these companies. After performing a research, it was found out that small and medium enterprises more than big organizations require a risk management strategy and methodology, need to distinguish activity objectives and events influencing them, and they can efficiently apply a risk portfolio method to manage risk. In small and medium enterprises it is recommended to incorporate a risk management system based on COSO ERM model that can be modified depending on company needs and possibilities, turning it into less formal and structured and easily applicable.

  18. The CTA medium size telescope prototype, a test bench for the array control software

    Energy Technology Data Exchange (ETDEWEB)

    Birsin, Emrah; Oya, Igor; Schwanke, Ullrich [Institut fuer Physik, Humboldt-Universitaet zu Berlin (Germany); Behera, Bagmeet; Koeppel, Hendryk; Melkumyan, David; Schmidt, Torsten; Wegner, Peter; Wiesand, Stephan; Winde, Michael [Deutsches Elektronen-Synchrotron, DESY, Zeuthen (Germany)

    2012-07-01

    CTA (Cherenkov Telescope Array) will be the largest ground-based gamma-ray observatory ever built. Two arrays are foreseen to be build, one in the Southern and one in the Northern hemisphere. A prototype for the Medium Size Telescope (MST) type (diameter: 12 m) will be installed in Berlin in early 2012. This MST prototype will be composed of the mechanical structure, drive system and mirror facets with an active mirror control system. The stability of the mechanical structure will be investigated with CCD cameras and a weather station. Furthermore the ALMA Common Software (ACS) distributed control framework will used as readout and control system for the MST, allowing to evaluate the software with the future use for the whole CTA array in mind. The design of the control software is following the concepts and tools under evaluation within the CTA consortium, like the use of a UML based code generation framework for ACS component modeling, and the use of OPC Unified Architecture (OPC UA) for hardware access. In this contribution the progress in the implementation of the control system for this CTA prototype telescope is described.

  19. Small- and medium-sized enterprises’ knowledge management systems as edifiers of new value innovations

    Directory of Open Access Journals (Sweden)

    Boniface Okanga

    2017-01-01

    Full Text Available Background: New value innovations are organically ingrained and complementary to the process of knowledge management. However, epistemological trends highlight only limited studies to have explored how the effectiveness of knowledge management leverages new value innovations.Objectives: This research evaluates how the effectiveness of the small- and medium-sized enterprises’ (SMEs knowledge management systems enhance new value innovations so as to identify the major paradoxes and a business model that coherently integrates knowledge management with new value innovations.Method: Using a qualitative research method, semi-structured interviews were used to explore the opinions of 20 purposively sampled managers from 20 SMEs on how knowledge management edifies new value innovations.Results: A strong culture of information utilisation was found to enhance relevant analysis and identification of new gaps in the markets that must be filled through new value innovations or modifications of the existing products. However, poor culture of knowledge utilisation, cost of knowledge management and the often poorly functional business information systems were still reiterated as major paradoxes hampering effective knowledge management as one of the determinants of new value innovations.Conclusion: The study concluded with a model highlighting a continuum of knowledge management–new value innovation pillars like a strong culture of information utilisation, and encouragement of creativity that the executives must consider to create an effective knowledge management foundation that subsequently leverages the overall effectiveness of new value innovations.

  20. The spatiotemporal trajectory of a dengue epidemic in a medium-sized city

    Directory of Open Access Journals (Sweden)

    Daniela G Morato

    2015-06-01

    Full Text Available Understanding the transmission dynamics of infectious diseases is important to allow for improvements of control measures. To investigate the spatiotemporal pattern of an epidemic dengue occurred at a medium-sized city in the Northeast Region of Brazil in 2009, we conducted an ecological study of the notified dengue cases georeferenced according to epidemiological week (EW and home address. Kernel density estimation and space-time interaction were analysed using the Knox method. The evolution of the epidemic was analysed using an animated projection technique. The dengue incidence was 6.918.7/100,000 inhabitants; the peak of the epidemic occurred from 8 February-1 March, EWs 6-9 (828.7/100,000 inhabitants. There were cases throughout the city and was identified space-time interaction. Three epicenters were responsible for spreading the disease in an expansion and relocation diffusion pattern. If the health services could detect in real time the epicenters and apply nimbly control measures, may possibly reduce the magnitude of dengue epidemics.

  1. Clinical audit of multidisciplinary care at a medium-sized hospital in Spain.

    Science.gov (United States)

    Ruiz-Casado, Ana; Ortega, María Jesús; Soria, Ana; Cebolla, Héctor

    2014-03-06

    Multidisciplinary care is a key enabler in the provision of high quality care for cancer patients. Despite compelling evidence supporting their benefit to patients and for providers, multidisciplinary cancer conferences (MCC) are not universally occurring. Team composition of MCC reflects the multidisciplinary nature of the body. Lack of nursing input can have a negative impact on team decision making. The objective of this study was to evaluate multidisciplinary care and adherence to national recommendations at a medium-sized hospital through a clinical audit of cancer conferences and clinical records. A total of 77 multidisciplinary cancer conferences were visited and 496 electronic health records were reviewed. The regularity of meetings and multidisciplinary attendance were evaluated. Each electronic health record was checked to verify documented prospective discussion before any treatment was started. Nine multidisciplinary teams meet on a weekly or biweekly basis at the hospital with an average number of ten people and six different specialties represented. Average duration of meetings was 46.8 min. Though most patients (64.5%) were discussed at some point at the relevant cancer conference, only 40% had a documented multidisciplinary team discussion prior to the first treatment. Pathological stage (pTNM) was documented in 53.6% of clinical records. Nursing representatives should be included as usual attendees at cancer conferences. Prospective discussion of all cancer cases should be encouraged. Use of checklists and systematic collection of key information, specifically cancer staging, could improve clinical documentation in the electronic clinical record.

  2. Microfinance: Diagnosis of the micro-business, medium-sized business and its financial technology

    Directory of Open Access Journals (Sweden)

    Emerson Toledo Concha

    2009-12-01

    Full Text Available This research work shows how the financing for micro and small businesses in Peru has increased and has greatlyexpanded in the last few years, not only in institutions specialized in this field, focused their efforts in giving financialservices to businesspeople of micro and medium-sized business, but most of the so-called traditional banks havefocused their attention to this emerging sector using the know-how of microfinance lending technology, banking seekto work with people of low income sectors, that were not subject for credit opportunities to develop their business andas a consequence not able to improve their quality of life .Throughout this investigation, we make a diagnosis of macro and micro environment of the microfinance field, itsdevelopment and expectations for a strong presence in the Peruvian financial market. We consider the development oflending technology, where the analysis of the ability and willingness to pay are the fundamental basis for the evaluationof credits in specialized companies in this sector.

  3. Creativity, creations and innovations in the management of small and medium-sized business

    Directory of Open Access Journals (Sweden)

    Usheva M.

    2015-05-01

    Full Text Available Creativity is a process of development and expression of new ideas interwoven in the company mission and vision to lead not only to financial success but also to real loyalty and involvement of the employees with the company problems and achievements. The main objective of this paper is through the research among contemporary managers and entrepreneurs, representatives of small and medium-sized business in the region of Blagoevgrad to prove that creativity skills are deployed in each person, to identify the specific characteristics of the creative thinking of the manager and the tools that stimulate them to increase competitiveness in the context of the sustainable development of the small and medium business in international and domestic tourism market. The main result to be achieved is evidence that when there is adequate (positive self-evaluation, intrinsic motivation or chiefly necessity of creativity manifestation, emotivity in the sense of creative enthusiasm, personal professional effectiveness and appropriate situational factors, the modern manager is able to model conditions for the manifestation of creativity (creative self-expression, both in themselves and in their subordinates. This in turn leads to increased competitiveness and intensive implementation of innovations in the company management and operation. The main research methods used in the study are literature review on the subject, survey, analysis of processes, intuitive and systematic approach, systematic observation, data classification and interpretation.

  4. Energy conserved and costs saved by small and medium-size manufacturers, 1988--1989

    Energy Technology Data Exchange (ETDEWEB)

    Kirsch, F.W.

    1991-05-01

    Energy Analysis and Diagnostic Centers (EADCs) provided energy-conserving and cost saving assistance in 339 small and medium-size manufacturing plants nationwide during 1988-89. This report presents the results of what was recommended to those manufacturers, the record of what was implemented by them, and an analysis of the financial rewards gained by them. It also includes an accounting of the financial returns to the federal government, derived from taxes upon the cost savings, or incremental income, of the manufacturers who implement the EADCs` recommendations. EADCs collect implementation data within a year of the energy audit, and for these results that time period extended through 1990. The EADCs are located at accredited engineering departments of universities and staffed by faculty and students. At present there are 18 EADCs serving manufacturers in 37 states; of these, two were established as a result of the 1989 competition, and five more were chosen competitively in 1990. Most of the results in this report were generated by 11 EADCs (named in the Appendix); two others withdrew voluntarily after completing only 10 energy audits during 1988-89. Primary responsibility for selecting, training, evaluating, and managing the EADCs belongs to the Industrial Technology and Energy Management (ITEM) division of University City Science Center (UCSC). The Department of Energy`s Office of Industrial Technologies sponsors the EADC program through an agreement with UCSC.

  5. submitter A High Precision 3D Magnetic Field Scanner for Small to Medium Size Magnets

    CERN Document Server

    Bergsma, F; Garnier, F; Giudici, P A

    2016-01-01

    A bench to measure the magnetic field of small to-medium-sized magnets with high precision was built. It uses a small-sized head with three orthogonal Hall probes, supported on a long pole at continuous movement during measurement. The head is calibrated in three dimensions by rotation over the full solid angle in a special device. From 0 to 2.5 T, the precision is ±0.2 mT in all components. The spatial range is 1 × 1 × 2 m with precision of ±0.02 mm. The bench and its controls are lightweight and easy to transport. The head can penetrate through small apertures and measure as close as 0.5 mm from the surface of a magnet. The bench can scan complicated grids in Cartesian or cylindrical coordinates, steered by a simple text file on an accompanying PC. The raw data is online converted to magnetic units and stored in a text file.

  6. Signaling from the cytoplasm to the nucleus in striatal medium-sized spiny neurons

    Directory of Open Access Journals (Sweden)

    Miriam eMatamales

    2011-07-01

    Full Text Available Striatal medium-sized spiny neurons (MSNs receive massive glutamate inputs from the cerebral cortex and thalamus and are a major target of dopamine projections. Interaction between glutamate and dopamine signaling is crucial for the control of movement and reward-driven learning, and its alterations are implicated in several neuropsychiatric disorders including Parkinson’s disease and drug addiction. Long-lasting forms of synaptic plasticity are thought to depend on transcription of gene products that alter the structure and/or function of neurons. Although multiple signal transduction pathways regulate transcription, little is known about signal transmission between the cytoplasm and the nucleus of striatal neurons and its regulation. Here we review the current knowledge of the signaling cascades that target the nucleus of MSNs, most of which are activated by cAMP and/or Ca2+. We outline the mechanisms by which signals originating at the plasma membrane and amplified in the cytoplasm are relayed to the nucleus, through the regulation of several protein kinases and phosphatases and transport through the nuclear pore. We also summarize the identified mechanisms of transcription regulation and chromatin remodeling in MSNs that appear to be important for behavioral adaptations, and discuss their relationships with epigenetic regulation.

  7. Respirable quartz exposure on two medium-sized farms in southern Mozambique.

    Science.gov (United States)

    Franque Mirembo, José C; Swanepoel, Andrew J; Rees, David

    2013-01-01

    Little is known about the potential for overexposure to respirable quartz in farming, in most parts of the world. To measure respirable dust and quartz exposure of tractor operators on two medium-sized dry climate farms. This is a descriptive cross-sectional study of dust exposure of four tractor operators. Farms were selected by convenience sampling. The MDHS 14/3 and FTIR MDHS 101 HSE methods were used to measure dust and to analyze the mass of quartz in dust, respectively. Seventy respirable dust measurements were done. Respirable dust and quartz ranged from 0·01 to 2·88 and 0·001 to 0·30 mg/m(3), respectively. All operators had at least one respirable quartz exposure above 0·1 mg/m(3). Only 17% of respirable quartz concentrations were lower than the ACGIH TLV of 0·025 mg/m(3). The potential for overexposure to respirable quartz was demonstrated. There was a great deal of exposure variability on these farms which has implications for sampling strategies for dust in farming.

  8. CRITICAL FACTORS IN OUTSOURCING OF ACCOUNTING FUNCTIONS IN MALAYSIAN SMALL MEDIUM-SIZED ENTERPRISES (SMEs

    Directory of Open Access Journals (Sweden)

    Magiswary Dorasamy

    2010-01-01

    Full Text Available The challenges that business face in sustaining competitive advantage in the corporate world have become a major concern. Businesses are adopting cutting-edge technologies and best practices to cope with rapid, global changes. Various business functions are being reengineered for this purpose. Accounting functions play an important role in helping businesses to maintain competitive advantage. However, some small and medium-sized enterprises (SMEs face problems handling fundamental accounting functions. This is predominantly because of their lack of expertise; accounting functions require not only knowledge of generally accepted accounting rules or tax regulations but also the expertise needed to apply the rules in a given business environment (Everaert, Sarens and Rommel, 2006. This paper offers some insight on the outsourcing of accounting functions as there is paucity of data in this area in the context of Malaysia. Essentially, it presents empirical evidence regarding Malaysian SMEs' accounting outsourcing practices. A survey of SMEs was conducted to identify the overall outsourcing landscape as it relates to accounting and third-party organisations. The factors that contribute to the decision to outsource accounting functions are analysed. The study reveals a significant relationship between outsourcing accounting functions and two contributing factors, risks and operation management.

  9. Specificities of the small and medium-sized enterprises in the Czech Republic and EU

    Directory of Open Access Journals (Sweden)

    Helena Chládková

    2010-01-01

    Full Text Available Small and medium enterprises (SME are the engine of the European economy. They are an essential source of jobs, create entrepreneurial spirit and innovation in the EU and are thus crucial for fostering competitiveness and employment. In the enlarged European Union of 27 countries, some 20 million SMEs provide around 75 million jobs and represent 99 % of all enterprises. However, they are often confronted with market imperfections. SMEs frequently have difficulties in obtaining capital or credit, particularly in the early start–up phase. Their limited resources may also restrict access to new technology or innovation. It is therefore necessary to monitor the development of SMEs in individual EU countries and highlighting their problems and mainly to their importance.During the recent period of time there have been many researchers from the FBE Mendel University in Brno, who focused on the analysis of the small and medium-sized enterprise, e.g. Bohušová (2007; Chládková (2009; Nerudová a Bohušová (2008; Kubíčková a Peprný (2006; Zrůst a Pyšný (2008. This paper is the part of the Research proposal MSM 6215648904 being solved at the FBE Mendel University in Brno.

  10. Hybrid neural intelligent system to predict business failure in small-to-medium-size enterprises.

    Science.gov (United States)

    Borrajo, M Lourdes; Baruque, Bruno; Corchado, Emilio; Bajo, Javier; Corchado, Juan M

    2011-08-01

    During the last years there has been a growing need of developing innovative tools that can help small to medium sized enterprises to predict business failure as well as financial crisis. In this study we present a novel hybrid intelligent system aimed at monitoring the modus operandi of the companies and predicting possible failures. This system is implemented by means of a neural-based multi-agent system that models the different actors of the companies as agents. The core of the multi-agent system is a type of agent that incorporates a case-based reasoning system and automates the business control process and failure prediction. The stages of the case-based reasoning system are implemented by means of web services: the retrieval stage uses an innovative weighted voting summarization of self-organizing maps ensembles-based method and the reuse stage is implemented by means of a radial basis function neural network. An initial prototype was developed and the results obtained related to small and medium enterprises in a real scenario are presented.

  11. Regional Determinants of Efficiency Growth of Small and Medium-Sized Enterprises. Evidence from Poland

    Directory of Open Access Journals (Sweden)

    Teresa Łuczka

    2012-01-01

    Full Text Available SMEs sector plays a vital role in modern economies. Therefore, the interest in its functioning among economists is in fact quite natural. This article is a part of a current research on regional factors contributing to the development of enterprises in this category. The first section examines earlier studies in this field conducted globally and in Poland. According to them, many elements enable the SME’s development. It is not surprisingly that the specified set of pro-growth factors does not exists. Next section describes the results of the author’s own studies in the fields. These studies relate to regional factors contributing to the efficiency growth of micro, small and medium-sized enterprises in Poland. Data used in the study was collected from GUS[1] and EUROSTAT and encompassed 16 provinces for the years 2003-2008. The model prepared included 11 independent variables on labor force, social mobility, living standard and R&D policy. The authors would have gladly considered more than 11 explanatory variable, but the inaccessibility of such data made it impossible. In the next step, using GRETL software, equations of regression were defined. On this basis it was concluded that the most important factors contributing to efficiency growth of SMEs are the amount of spending on R&D and the level of wages.

  12. Resource efficiency and culture--workplace training for small and medium-sized enterprises.

    Science.gov (United States)

    Bliesner, Anna; Liedtke, Christa; Rohn, Holger

    2014-05-15

    Although there are already some qualification offers available for enterprises to support resource efficiency innovations, the high potentials that can be identified especially for small and medium sized enterprises (SMEs) have not been activated until now. As successful change lies in the hands of humans, the main aim of vocational education has to be the promotion of organisational and cultural changes in the enterprises. As there is already a small but increasing number of enterprises that perform very well in resource efficiency innovations one question arises: What are typical characteristics of those enterprises? Leaning on a good-practice approach, the project "ResourceCulture" is going to prove or falsify the hypothesis that enterprises being successful with resource efficiency innovations have a specific culture of trust, which substantially contributes to innovation processes, or even initially enables them. Detailed empirical field research will light up which correlations between resource efficiency, innovation and cultures of trust can be found and will offer important aspects for the improvement of management instruments and qualification concepts for workplace training. The project seizes qualification needs that were likewise mentioned by enterprises and consultants, regarding the implementation of resource efficiency. This article - based on first empirical field research results - derives preliminary indications for the design of the qualification module for the target groups resource efficiency consultants and managers. On this basis and in order to implement "ResourceCulture" conceptual and methodological starting points for workplace training are outlined. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. Feasibility of a medium-size central cogenerated energy facility, energy management memorandum

    Science.gov (United States)

    Porter, R. W.

    1982-09-01

    The thermal-economic feasibility was studied of a medium-size central cogenerated energy facility designed to serve five varied industries. Generation options included one dual-fuel diesel and one gas turbine, both with waste heat boilers, and five fired boilers. Fuels included natural gas, and for the fired-boiler cases, also low-sulphur coal and municipal refuse. The fired-boiler cogeneration systems employed back-pressure steam turbines. For coal and refuse, the option of steam only without cogeneration was also assessed. The refuse-fired cases utilized modular incinerators. The options provided for a wide range of steam and electrical capacities. Deficient steam was assumed generated independently in existing equipment. Excess electrical power over that which could be displaced was assumed sold to Commonwealth Edison Company under PURPA (Public Utility Regulator Policies Act). The facility was assumed operated by a mutually owned corporation formed by the cogenerated power users. The economic analysis was predicted on currently applicable energy-investment tax credits and accelerated depreciation for a January 1985 startup date. Based on 100% equity financing, the results indicated that the best alternative was the modular-incinerator cogeneration system.

  14. ADVANCED CONTROL OF A COMPLEX CHEMICAL PROCESS

    OpenAIRE

    Both,Roxana; Dulf,Eva-Henrietta; Cormos,Ana-Maria

    2016-01-01

    Abstract Three phase catalytic hydrogenation reactors are important reactors with complex behavior due to the interaction among gas, solid and liquid phases with the kinetic, mass and heat transfer mechanisms. A nonlinear distributed parameter model was developed based on mass and energy conservation principles. It consists of balance equations for the gas and liquid phases, so that a system of partial differential equations is generated. Because detailed nonlinear mathematical models are not...

  15. The chemical complexity of Yaji : A Nigerian Suya meat sauce ...

    African Journals Online (AJOL)

    Therefore, for completeness sake as regards the knowledge on Yaji, this review paper examines its chemical complexity with a view of providing information that would justify the need for the regulation of Yaji production on one hand, and the need for a moderated consumption on the other; considering the chemical ...

  16. Heats of Formation of Medium-Size Organic Compounds from Contemporary Electronic Structure Methods

    KAUST Repository

    Minenkov, Yury

    2017-06-21

    Computational electronic structure calculations are routinely undertaken to predict thermodynamic properties of the various species. However, the application of highly accurate wave function theory methods, such as the “gold standard” coupled cluster approach including single, double and partly triple excitations in perturbative fashion, CCSD(T), to large molecules is limited due to high computational cost. In this work, the promising domain based local pair natural orbital coupled cluster approach, DLPNO-CCSD(T), has been tested to reproduce 113 accurate formation enthalpies of medium-size molecules (few dozens heavy atoms) important for bio- and combustion chemistry via the reaction based Feller-Peterson-Dixon approach. As for comparison, 8 density functional theory (B3LYP, B3LYP-D3, PBE0, PBE0-D3, M06, M06-2X, ωB97X-D3, and ωB97M-V) and MP2-based (B2PLYP-D3, PWPB95-D3, B2T-PLYP, B2T-PLYP-D, B2GP-PLYP, DSD-PBEP86-D3, SCS-MP2, and OO-SCS-MP2) methods have been tested. The worst performance has been obtained for the standard hybrid DFT functionals, PBE0 (Mean unsigned error (MUE)/ Mean Signed Error (MSE)=9.1/6.0 kcal/mol) and B3LYP (MUE/MSE=13.5/-13.3 kcal/mol). An influence of an empirical dispersion correction term on these functionals performance is not homogenous: B3LYP performance is improved (B3LYP-D3 (MUE/MSE=6.0/0.8 kcal/mol)) meanwhile PBE0 performance is worse (PBE0-D3 (MUE/MSE=14.1/13.6 kcal/mol)). The Minnesota functionals, M06 (MUE/MSE=3.8/-2.0 kcal/mol) and M06-2X (MUE/MSE=3.5/3.0 kcal/mol), and recently developed ωB97X-D3 (MUE/MSE=3.2/0.2 kcal/mol) and ωB97M-V (MUE/MSE=2.2/1.3 kcal/mol) methods provided significantly better formation enthalpies. Enthalpies of similar quality can also be obtained from some double hybrid methods (B2PLYP-D3 (MUE/MSE=4.7/2.0 kcal/mol), PWPB95-D3 (MUE/MSE=4.3/3.2 kcal/mol), B2T-PLYP (MUE/MSE=4.1/-3.0 kcal/mol) and B2T-PLYP-D (MUE/MSE=3.3/1.7 kcal/mol)). The two spin component scaled (SCS) MP2 methods resulted in

  17. THE RELATIONSHIP BETWEEN SMALL AND MEDIUM-SIZED ENTERPRISES, TOURISM AND ECONOMIC DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Tatjana Dimoska

    2015-01-01

    Full Text Available Tourism is the world’s largest industry and makes a major contribution to the economies of most developed and developing countries. Tourism as an important socio-economical phenomenon is characterized with distinctly largeness and dynamic development that results with many positive direct as well as indirect economical effects. That is a measure for increasing of possibilities of encouragement of the total economical development through tourism development. Tourism generates income from consumption of goods and services by tourists as well as taxes on businesses in the tourism industry, provides employment in services related to tourism, but also creates jobs in the tertiary sector, generates growth of primary and secondary sectors of the industry as result of multiplicative effect. In this context especially are important small and medium tourism enterprises which dominate in the tourism destinations according to their number, originating a variety of benefits for the tourism destinations by providing direct contact with tourists and by encouraging tourist for spending in a local community. The aim of this paper is to point out the importance of small and medium –sized enterprises in general and especially in the field of tourism for increasing economic development in the national economy with particular reference on the territory of the Republic of Macedonia. In this paper, first will be analyzed the term small and medium - sized enterprises in general and then will be explained their application in the field of tourism with highlighting of their strategic advantages for the tourism destinations and overall economic development of the entire national economy. Finally, will be analyzed the role played by SMEs for the economic development of the Republic of Macedonia with a special emphasis on the measures and actions which have to be taken in the future by the competent authorities for further stimulation of their development.

  18. Effects of urban green areas on air temperature in a medium-sized Argentinian city

    Directory of Open Access Journals (Sweden)

    Alejandra S. Coronel

    2015-07-01

    Full Text Available Urban climate is the result of both atmospheric and geographic factors affecting a region, as well as the morphology, structures and human activities in a city. Urban vegetation in particular affects this climate at a local scale and provides many other social, economic and ecological benefits. Thus, it is important to explore the effects of different green areas used for urban and periurban agriculture and forestry activities (UPAF on daily atmospheric temperature and the required degrees of cooling or refrigerating temperature. Comfort temperatures were defined using a range 18-24°C and analyzed using actual measured as well as forecasted temperatures using a future scenario. Actual temperatures were recorded from September 2013 to August 2014 using digital sensors across eight sites in Rosario, Argentina: three in the central core with no vegetation, one in the central core with street trees, one in an urban agriculture site, one in a public park and two in periurban agricultural areas. Results show that air temperature in the central core with no vegetation were higher than those in other sites with vegetation during day and night, with the exception of the temperatures measured at the central core site with street trees. Findings also show that temperature effects in urban agricultural gardens of approximately 0.2 ha were similar to those of gardens and public parks 2-3 ha in size. Three UPAF types were classified according to cooling degree days, which decreased in order from (1 central core with no trees; (2 central core with street trees and public parks; and (3 urban and periurban agriculture areas. Conversely, the opposite trends for heating degree days were found. Results from this study can be used for integrating UPAF measures into climate change mitigation and urban planning policies in medium-sized cities in the developing world.

  19. Urbanization alters communities of flying arthropods in parks and gardens of a medium-sized city

    Directory of Open Access Journals (Sweden)

    Edward Lagucki

    2017-09-01

    Full Text Available Urbanization transforms undeveloped landscapes into built environments, causing changes in communities and ecological processes. Flying arthropods play important roles in these processes as pollinators, decomposers, and predators, and can be important in structuring food webs. The goal of this study was to identify associations between urbanization and the composition of communities of flying (and floating arthropods within gardens and parks in a medium-sized mesic city. We predicted that flying arthropod abundance and diversity would respond strongly to percent impervious surface and distance to city center, measurements of urbanization. Flying arthropods were sampled from 30 gardens and parks along an urbanization gradient in Toledo, Ohio, during July and August 2016, using elevated pan traps. A variety of potential predictor variables were also recorded at each site. We collected a total of 2,369 individuals representing nine orders. We found that flying arthropod community composition was associated with percent impervious surface and canopy cover. Overall flying arthropod abundance was negatively associated with percent impervious surface and positively associated with distance to city center. Hymenoptera (bees, wasps, ants, Lepidoptera (moths, butterflies, and Araneae (spiders were positively associated with distance to city center. Hemiptera (true bugs, Diptera (flies, and Araneae were negatively associated with percent impervious surface. Both distance to city center and percent impervious surface are metrics of urbanization, and this study shows how these factors influence flying arthropod communities in urban gardens and city parks, including significant reductions in taxa that contain pollinators and predators important to urban agriculture and forestry. A variety of environmental factors also showed significant associations with responses (e.g. canopy cover and soil moisture, suggesting these factors may underlie or modulate the

  20. Urbanization alters communities of flying arthropods in parks and gardens of a medium-sized city.

    Science.gov (United States)

    Lagucki, Edward; Burdine, Justin D; McCluney, Kevin E

    2017-01-01

    Urbanization transforms undeveloped landscapes into built environments, causing changes in communities and ecological processes. Flying arthropods play important roles in these processes as pollinators, decomposers, and predators, and can be important in structuring food webs. The goal of this study was to identify associations between urbanization and the composition of communities of flying (and floating) arthropods within gardens and parks in a medium-sized mesic city. We predicted that flying arthropod abundance and diversity would respond strongly to percent impervious surface and distance to city center, measurements of urbanization. Flying arthropods were sampled from 30 gardens and parks along an urbanization gradient in Toledo, Ohio, during July and August 2016, using elevated pan traps. A variety of potential predictor variables were also recorded at each site. We collected a total of 2,369 individuals representing nine orders. We found that flying arthropod community composition was associated with percent impervious surface and canopy cover. Overall flying arthropod abundance was negatively associated with percent impervious surface and positively associated with distance to city center. Hymenoptera (bees, wasps, ants), Lepidoptera (moths, butterflies), and Araneae (spiders) were positively associated with distance to city center. Hemiptera (true bugs), Diptera (flies), and Araneae were negatively associated with percent impervious surface. Both distance to city center and percent impervious surface are metrics of urbanization, and this study shows how these factors influence flying arthropod communities in urban gardens and city parks, including significant reductions in taxa that contain pollinators and predators important to urban agriculture and forestry. A variety of environmental factors also showed significant associations with responses (e.g. canopy cover and soil moisture), suggesting these factors may underlie or modulate the urbanization

  1. Uncertainty evaluation of reliability of shutdown system of a medium size fast breeder reactor

    Energy Technology Data Exchange (ETDEWEB)

    Zeliang, Chireuding; Singh, Om Pal, E-mail: singhop@iitk.ac.in; Munshi, Prabhat

    2016-11-15

    Highlights: • Uncertainty analysis of reliability of Shutdown System is carried out. • Monte Carlo method of sampling is used. • The effect of various reliability improvement measures of SDS are accounted. - Abstract: In this paper, results are presented on the uncertainty evaluation of the reliability of Shutdown System (SDS) of a Medium Size Fast Breeder Reactor (MSFBR). The reliability analysis results are of Kumar et al. (2005). The failure rate of the components of SDS are taken from International literature and it is assumed that these follow log-normal distribution. Fault tree method is employed to propagate the uncertainty in failure rate from components level to shutdown system level. The beta factor model is used to account different extent of diversity. The Monte Carlo sampling technique is used for the analysis. The results of uncertainty analysis are presented in terms of the probability density function, cumulative distribution function, mean, variance, percentile values, confidence intervals, etc. It is observed that the spread in the probability distribution of SDS failure rate is less than SDS components failure rate and ninety percent values of the failure rate of SDS falls below the target value. As generic values of failure rates are used, sensitivity analysis is performed with respect to failure rate of control and safety rods and beta factor. It is discovered that a large increase in failure rate of SDS rods is not carried to SDS system failure proportionately. The failure rate of SDS is very sensitive to the beta factor of common cause failure between the two systems of SDS. The results of the study provide insight in the propagation of uncertainty in the failure rate of SDS components to failure rate of shutdown system.

  2. Factors preceding CRM readiness in small- and medium-sized tourism enterprises

    Directory of Open Access Journals (Sweden)

    Dinesh Vallabh

    2015-02-01

    Full Text Available Orientation: Customer relationship management (CRM is important to organisations striving for competitive advantage through building relationships with their customers.Research purpose: This study identified the factors preceding CRM and assessed selected South African small- and medium-sized tourism enterprises’ (SMTEs readiness for CRM.Motivation: CRM is likely to enhance SMTEs’ competitiveness. However, successful adoption and implementation of CRM is unlikely unless the organisation is ready for it.Research design, approach and method: A quantitative research approach and survey questionnaire yielded primary data from 332 respondent organisations selected by systematic sampling. Exploratory factor analysis was used to identify the latent factors preceding CRM readiness. Organisational CRM readiness was assessed based on CRM maturity in terms of data collection, use and sharing throughout the organisation.Main findings: Respondent-organisations performed well on the four factors preceding CRM readiness − business strategy, customer strategy, touch points and competencies, skills and technology and also on data collections and use, but not on data sharing.Practical/Managerial implications: CRM practice is believed to assist organisations in tailoring products and services to customers’ needs, providing customer satisfaction, enhancing customer retention and ultimately improving the organisation’s competitiveness and profitability. CRM might fail if SMTEs do not have CRM-enabling conditions in place and a CRM readiness audit should therefore be performed.Contribution: The study contributes to a largely under-researched area concerning CRM in SMTEs by providing an improved understanding of the factors that will enable SMTEs to engage in CRM activities.

  3. Risk Factors for Motorcycle-related Severe Injuries in a Medium-sized City in China

    Directory of Open Access Journals (Sweden)

    Xiong Lili

    2016-11-01

    Full Text Available Background: Motorcycle vehicles are frequent in China, especially in the small and medium sized cities. Road traffic collisions involving motorcycles often result in severe injuries. We aimed to identify risk factors for severe injuries in inpatients sustaining motorcycle collisions. Methods: Patients with road traffic injuries involving motorcycles who presented to the neurosurgery and orthopedic departments of three major comprehensive hospitals in Shantou city were reviewed from October 2012 to June 2013. Data from 349 patients was investigated. Crash and injury characteristics were documented by interviewing patients, their family members, and their doctors. Binary logistic regression was used to determine risk factors for severe injuries. Results: There were 253 males (72.49% and 96 females (27.51%, with a male to female ratio of 2.64:1. The mean age was 38.21 ± 17.32 years. One-hundred and fifty patients were in the severe injury group with a mean injury severity score (ISS of 15.34 ± 9.13. The simple and multiple logistic model showed that males, lack of safeguards, morning and night hours, non-urban areas, collision of a motorcycle with a cycle, ambulance transportation to hospital, admission to a neurosurgery department, lack of traffic control, unobstructed traffic, and poor visibility were all the risk factors. Conclusions: This research highlights some problems: less helmet wearing in motorcyclists and cyclists, rural injuries being more serious than urban ones, and head injuries being the main diagnosis in severe injuries. The result of this research is predictable. If the safety equipment is required to be used, such as helmets, and the traffic environment is improved, such as traffic flow, medical resources to injuries and deaths is seasonable, then traffic safety will be improved and accidents will be reduced.

  4. Overview of progress in European medium sized tokamaks towards an integrated plasma-edge/wall solution

    Science.gov (United States)

    Meyer, H.; Eich, T.; Beurskens, M.; Coda, S.; Hakola, A.; Martin, P.; Adamek, J.; Agostini, M.; Aguiam, D.; Ahn, J.; Aho-Mantila, L.; Akers, R.; Albanese, R.; Aledda, R.; Alessi, E.; Allan, S.; Alves, D.; Ambrosino, R.; Amicucci, L.; Anand, H.; Anastassiou, G.; Andrèbe, Y.; Angioni, C.; Apruzzese, G.; Ariola, M.; Arnichand, H.; Arter, W.; Baciero, A.; Barnes, M.; Barrera, L.; Behn, R.; Bencze, A.; Bernardo, J.; Bernert, M.; Bettini, P.; Bilková, P.; Bin, W.; Birkenmeier, G.; Bizarro, J. P. S.; Blanchard, P.; Blanken, T.; Bluteau, M.; Bobkov, V.; Bogar, O.; Böhm, P.; Bolzonella, T.; Boncagni, L.; Botrugno, A.; Bottereau, C.; Bouquey, F.; Bourdelle, C.; Brémond, S.; Brezinsek, S.; Brida, D.; Brochard, F.; Buchanan, J.; Bufferand, H.; Buratti, P.; Cahyna, P.; Calabrò, G.; Camenen, Y.; Caniello, R.; Cannas, B.; Canton, A.; Cardinali, A.; Carnevale, D.; Carr, M.; Carralero, D.; Carvalho, P.; Casali, L.; Castaldo, C.; Castejón, F.; Castro, R.; Causa, F.; Cavazzana, R.; Cavedon, M.; Cecconello, M.; Ceccuzzi, S.; Cesario, R.; Challis, C. D.; Chapman, I. T.; Chapman, S.; Chernyshova, M.; Choi, D.; Cianfarani, C.; Ciraolo, G.; Citrin, J.; Clairet, F.; Classen, I.; Coelho, R.; Coenen, J. W.; Colas, L.; Conway, G.; Corre, Y.; Costea, S.; Crisanti, F.; Cruz, N.; Cseh, G.; Czarnecka, A.; D'Arcangelo, O.; De Angeli, M.; De Masi, G.; De Temmerman, G.; De Tommasi, G.; Decker, J.; Delogu, R. S.; Dendy, R.; Denner, P.; Di Troia, C.; Dimitrova, M.; D'Inca, R.; Dorić, V.; Douai, D.; Drenik, A.; Dudson, B.; Dunai, D.; Dunne, M.; Duval, B. P.; Easy, L.; Elmore, S.; Erdös, B.; Esposito, B.; Fable, E.; Faitsch, M.; Fanni, A.; Fedorczak, N.; Felici, F.; Ferreira, J.; Février, O.; Ficker, O.; Fietz, S.; Figini, L.; Figueiredo, A.; Fil, A.; Fishpool, G.; Fitzgerald, M.; Fontana, M.; Ford, O.; Frassinetti, L.; Fridström, R.; Frigione, D.; Fuchert, G.; Fuchs, C.; Furno Palumbo, M.; Futatani, S.; Gabellieri, L.; Gałązka, K.; Galdon-Quiroga, J.; Galeani, S.; Gallart, D.; Gallo, A.; Galperti, C.; Gao, Y.; Garavaglia, S.; Garcia, J.; Garcia-Carrasco, A.; Garcia-Lopez, J.; Garcia-Munoz, M.; Gardarein, J.-L.; Garzotti, L.; Gaspar, J.; Gauthier, E.; Geelen, P.; Geiger, B.; Ghendrih, P.; Ghezzi, F.; Giacomelli, L.; Giannone, L.; Giovannozzi, E.; Giroud, C.; Gleason González, C.; Gobbin, M.; Goodman, T. P.; Gorini, G.; Gospodarczyk, M.; Granucci, G.; Gruber, M.; Gude, A.; Guimarais, L.; Guirlet, R.; Gunn, J.; Hacek, P.; Hacquin, S.; Hall, S.; Ham, C.; Happel, T.; Harrison, J.; Harting, D.; Hauer, V.; Havlickova, E.; Hellsten, T.; Helou, W.; Henderson, S.; Hennequin, P.; Heyn, M.; Hnat, B.; Hölzl, M.; Hogeweij, D.; Honoré, C.; Hopf, C.; Horáček, J.; Hornung, G.; Horváth, L.; Huang, Z.; Huber, A.; Igitkhanov, J.; Igochine, V.; Imrisek, M.; Innocente, P.; Ionita-Schrittwieser, C.; Isliker, H.; Ivanova-Stanik, I.; Jacobsen, A. S.; Jacquet, P.; Jakubowski, M.; Jardin, A.; Jaulmes, F.; Jenko, F.; Jensen, T.; Jeppe Miki Busk, O.; Jessen, M.; Joffrin, E.; Jones, O.; Jonsson, T.; Kallenbach, A.; Kallinikos, N.; Kálvin, S.; Kappatou, A.; Karhunen, J.; Karpushov, A.; Kasilov, S.; Kasprowicz, G.; Kendl, A.; Kernbichler, W.; Kim, D.; Kirk, A.; Kjer, S.; Klimek, I.; Kocsis, G.; Kogut, D.; Komm, M.; Korsholm, S. B.; Koslowski, H. R.; Koubiti, M.; Kovacic, J.; Kovarik, K.; Krawczyk, N.; Krbec, J.; Krieger, K.; Krivska, A.; Kube, R.; Kudlacek, O.; Kurki-Suonio, T.; Labit, B.; Laggner, F. M.; Laguardia, L.; Lahtinen, A.; Lalousis, P.; Lang, P.; Lauber, P.; Lazányi, N.; Lazaros, A.; Le, H. B.; Lebschy, A.; Leddy, J.; Lefévre, L.; Lehnen, M.; Leipold, F.; Lessig, A.; Leyland, M.; Li, L.; Liang, Y.; Lipschultz, B.; Liu, Y. Q.; Loarer, T.; Loarte, A.; Loewenhoff, T.; Lomanowski, B.; Loschiavo, V. P.; Lunt, T.; Lupelli, I.; Lux, H.; Lyssoivan, A.; Madsen, J.; Maget, P.; Maggi, C.; Maggiora, R.; Magnussen, M. L.; Mailloux, J.; Maljaars, B.; Malygin, A.; Mantica, P.; Mantsinen, M.; Maraschek, M.; Marchand, B.; Marconato, N.; Marini, C.; Marinucci, M.; Markovic, T.; Marocco, D.; Marrelli, L.; Martin, Y.; Solis, J. R. Martin; Martitsch, A.; Mastrostefano, S.; Mattei, M.; Matthews, G.; Mavridis, M.; Mayoral, M.-L.; Mazon, D.; McCarthy, P.; McAdams, R.; McArdle, G.; McCarthy, P.; McClements, K.; McDermott, R.; McMillan, B.; Meisl, G.; Merle, A.; Meyer, O.; Milanesio, D.; Militello, F.; Miron, I. G.; Mitosinkova, K.; Mlynar, J.; Mlynek, A.; Molina, D.; Molina, P.; Monakhov, I.; Morales, J.; Moreau, D.; Morel, P.; Moret, J.-M.; Moro, A.; Moulton, D.; Müller, H. W.; Nabais, F.; Nardon, E.; Naulin, V.; Nemes-Czopf, A.; Nespoli, F.; Neu, R.; Nielsen, A. H.; Nielsen, S. K.; Nikolaeva, V.; Nimb, S.; Nocente, M.; Nouailletas, R.; Nowak, S.; Oberkofler, M.; Oberparleiter, M.; Ochoukov, R.; Odstrčil, T.; Olsen, J.; Omotani, J.; O'Mullane, M. G.; Orain, F.; Osterman, N.; Paccagnella, R.; Pamela, S.; Pangione, L.; Panjan, M.; Papp, G.; Papřok, R.; Parail, V.; Parra, F. I.; Pau, A.; Pautasso, G.; Pehkonen, S.-P.; Pereira, A.; Perelli Cippo, E.; Pericoli Ridolfini, V.; Peterka, M.; Petersson, P.; Petrzilka, V.; Piovesan, P.; Piron, C.; Pironti, A.; Pisano, F.; Pisokas, T.; Pitts, R.; Ploumistakis, I.; Plyusnin, V.; Pokol, G.; Poljak, D.; Pölöskei, P.; Popovic, Z.; Pór, G.; Porte, L.; Potzel, S.; Predebon, I.; Preynas, M.; Primc, G.; Pucella, G.; Puiatti, M. E.; Pütterich, T.; Rack, M.; Ramogida, G.; Rapson, C.; Rasmussen, J. Juul; Rasmussen, J.; Rattá, G. A.; Ratynskaia, S.; Ravera, G.; Réfy, D.; Reich, M.; Reimerdes, H.; Reimold, F.; Reinke, M.; Reiser, D.; Resnik, M.; Reux, C.; Ripamonti, D.; Rittich, D.; Riva, G.; Rodriguez-Ramos, M.; Rohde, V.; Rosato, J.; Ryter, F.; Saarelma, S.; Sabot, R.; Saint-Laurent, F.; Salewski, M.; Salmi, A.; Samaddar, D.; Sanchis-Sanchez, L.; Santos, J.; Sauter, O.; Scannell, R.; Scheffer, M.; Schneider, M.; Schneider, B.; Schneider, P.; Schneller, M.; Schrittwieser, R.; Schubert, M.; Schweinzer, J.; Seidl, J.; Sertoli, M.; Šesnić, S.; Shabbir, A.; Shalpegin, A.; Shanahan, B.; Sharapov, S.; Sheikh, U.; Sias, G.; Sieglin, B.; Silva, C.; Silva, A.; Silva Fuglister, M.; Simpson, J.; Snicker, A.; Sommariva, C.; Sozzi, C.; Spagnolo, S.; Spizzo, G.; Spolaore, M.; Stange, T.; Stejner Pedersen, M.; Stepanov, I.; Stober, J.; Strand, P.; Šušnjara, A.; Suttrop, W.; Szepesi, T.; Tál, B.; Tala, T.; Tamain, P.; Tardini, G.; Tardocchi, M.; Teplukhina, A.; Terranova, D.; Testa, D.; Theiler, C.; Thornton, A.; Tolias, P.; Tophøj, L.; Treutterer, W.; Trevisan, G. L.; Tripsky, M.; Tsironis, C.; Tsui, C.; Tudisco, O.; Uccello, A.; Urban, J.; Valisa, M.; Vallejos, P.; Valovic, M.; Van den Brand, H.; Vanovac, B.; Varoutis, S.; Vartanian, S.; Vega, J.; Verdoolaege, G.; Verhaegh, K.; Vermare, L.; Vianello, N.; Vicente, J.; Viezzer, E.; Vignitchouk, L.; Vijvers, W. A. J.; Villone, F.; Viola, B.; Vlahos, L.; Voitsekhovitch, I.; Vondráček, P.; Vu, N. M. T.; Wagner, D.; Walkden, N.; Wang, N.; Wauters, T.; Weiland, M.; Weinzettl, V.; Westerhof, E.; Wiesenberger, M.; Willensdorfer, M.; Wischmeier, M.; Wodniak, I.; Wolfrum, E.; Yadykin, D.; Zagórski, R.; Zammuto, I.; Zanca, P.; Zaplotnik, R.; Zestanakis, P.; Zhang, W.; Zoletnik, S.; Zuin, M.; ASDEX Upgrade, the; MAST; TCV Teams

    2017-10-01

    Integrating the plasma core performance with an edge and scrape-off layer (SOL) that leads to tolerable heat and particle loads on the wall is a major challenge. The new European medium size tokamak task force (EU-MST) coordinates research on ASDEX Upgrade (AUG), MAST and TCV. This multi-machine approach within EU-MST, covering a wide parameter range, is instrumental to progress in the field, as ITER and DEMO core/pedestal and SOL parameters are not achievable simultaneously in present day devices. A two prong approach is adopted. On the one hand, scenarios with tolerable transient heat and particle loads, including active edge localised mode (ELM) control are developed. On the other hand, divertor solutions including advanced magnetic configurations are studied. Considerable progress has been made on both approaches, in particular in the fields of: ELM control with resonant magnetic perturbations (RMP), small ELM regimes, detachment onset and control, as well as filamentary scrape-off-layer transport. For example full ELM suppression has now been achieved on AUG at low collisionality with n  =  2 RMP maintaining good confinement {{H}\\text{H≤ft(98,\\text{y}2\\right)}}≈ 0.95 . Advances have been made with respect to detachment onset and control. Studies in advanced divertor configurations (Snowflake, Super-X and X-point target divertor) shed new light on SOL physics. Cross field filamentary transport has been characterised in a wide parameter regime on AUG, MAST and TCV progressing the theoretical and experimental understanding crucial for predicting first wall loads in ITER and DEMO. Conditions in the SOL also play a crucial role for ELM stability and access to small ELM regimes. In the future we will refer to the author list of the paper as the EUROfusion MST1 Team.

  5. Extension of association models to complex chemicals

    DEFF Research Database (Denmark)

    Avlund, Ane Søgaard

    Summary of “Extension of association models to complex chemicals”. Ph.D. thesis by Ane Søgaard Avlund The subject of this thesis is application of SAFT type equations of state (EoS). Accurate and predictive thermodynamic models are important in many industries including the petroleum industry....... The SAFT EoS was developed 20 years ago, and a large number of papers on the subject has been published since, but many issues still remain unsolved. These issues are both theoretical and practical. The SAFT theory does not account for intramolecular association, it can only treat flexible chains, and does...... functional groups. It is also tested whether increasing the number of sites for DEA (diethanolamine) improves the results. It can be shown from experimental data that intramolecular association is dominating compared to intermolecular association in certain systems, and that the intramolecular association...

  6. ADVANCED CONTROL OF A COMPLEX CHEMICAL PROCESS

    Directory of Open Access Journals (Sweden)

    Roxana Both

    Full Text Available Abstract Three phase catalytic hydrogenation reactors are important reactors with complex behavior due to the interaction among gas, solid and liquid phases with the kinetic, mass and heat transfer mechanisms. A nonlinear distributed parameter model was developed based on mass and energy conservation principles. It consists of balance equations for the gas and liquid phases, so that a system of partial differential equations is generated. Because detailed nonlinear mathematical models are not suitable for use in controller design, a simple linear mathematical model of the process, which describes its most important properties, was determined. Both developed mathematical models were validated using plant data. The control strategies proposed in this paper are a multivariable Smith Predictor PID controller and multivariable Smith Predictor structure in which the primary controllers are derived based on Internal Model Control. Set-point tracking and disturbance rejection tests are presented for both methods based on scenarios implemented in Matlab/SIMULINK.

  7. Chemometrics as a tool to analyse complex chemical mixtures

    DEFF Research Database (Denmark)

    Christensen, Jan Henning

    Chemical characterisation of contaminant mixtures is important for environmental forensics and risk assessment. The great challenge in future research lies in develop- ing suitable, rapid, reliable and objective methods for analysis of the composition of complex chemical mixtures. This thesis...... and at the same time must consider a substantial fraction of compounds in the complex mixture. A combination of a) limited sample preparation, b) rapid chemical screening analysis, c) fast and semi-automatic pre-processing, d) compre- hensive multivariate statistical data analysis and e) objective data evaluation...

  8. IFRS IN THE SMALL AND MEDIUM-SIZED ENTITIES. DIFICULTIES AND OPPORTUNITIES OF THE IFRS FOR SMES

    OpenAIRE

    Moț Ioana

    2013-01-01

    IFRS IN THE SMALL AND MEDIUM-SIZED ENTITIES. DIFICULTIES AND OPPORTUNITIES OF THE IFRS FOR SMEs PhD Student Moț Ioana, West University of Timișoara, Faculty of Economics and Business Administration, România Doctoral programme - Accounting Scientific coordonator - Prof. Univ. Dr. Mateș Dorel

  9. In Good Company : When Small and Medium-sized Enterprises Acquire Multiplex Knowledge from Key Commercial Partners

    NARCIS (Netherlands)

    Bojica, Ana M.; Estrada Vaquero, Isabel; Fuentes, Maria M

    2018-01-01

    This study explores the specific conditions under which key strategic alliances of small and medium-sized enterprises (SMEs) with commercial partners can become multiplex in knowledge exchange. Using survey data from a sample of 150 Spanish SMEs in the information and communication technology (ICT)

  10. Presenting a framework to analyze local climate policy and action in small and medium-sized cities

    NARCIS (Netherlands)

    Hoppe, T.; van der Vegt, Arjen; Stegmaier, Peter

    2016-01-01

    Academic attention to local climate policy usually focuses on large-sized cities. Given the climate challenges ahead this seems unjustified. Small and medium-sized cities (SMCs) deserve scholarly attention as well. The main question is: What factors influence climate change policy and local

  11. UCD4SME : Small to Medium-sized Enterprises involving their users and clients for product innovation

    NARCIS (Netherlands)

    De Lille, C.S.H.

    2014-01-01

    An increasing number of Small to Medium-sized Enterprises (SMEs) starts to realize the opportunities offered by User-centred Design (UCD). The issue is that our understanding of UCD either comes from large companies or is developed in an academic setting, without taking SMEs into account. This

  12. Argentina - Small and Medium-Sized Enterprises in Argentina : A Potential Engine for Economic Growth and Employment

    OpenAIRE

    World Bank

    2002-01-01

    The convertibility law, and economic liberalization in the early 1990s in Argentina, brought about dramatic changes in economic performance. To adjust to increasing globalization, and a series of external shocks, small and medium size enterprises (SMEs) were confronted with the task of developing business strategies to secure their niches in the new arena. However, such strategies were obs...

  13. Exploring corporate sustainability integration into business activities. Experiences from 18 small and medium sized enterprises in the Netherlands

    NARCIS (Netherlands)

    Witjes, S.; Vermeulen, W.J.V.; Cramer, J.M.

    Although companies have shown a growing awareness of the importance of Corporate Sustainability (CS), integration of CS into their business activities is still problematic. Most of the CS research focuses on large corporations, with limited discussions of Small and Medium Sized Enterprises (SMEs).

  14. Using Computer-Based Continuing Professional Education of Training Staff to Develop Small- and Medium-Sized Enterprises in Thailand

    Science.gov (United States)

    Sooraksa, Nanta

    2012-01-01

    This paper describes a career development program for staff involved in providing training for small- and medium-sized enterprises (SMEs) in Thailand. Most of these staff were professional vocational teachers in schools. The program uses information communication technology (ICT), and its main objective is to teach Moodle software as a tool for…

  15. The Anonymity of Catalan and the Authenticity of Estonian: Two Paths for the Development of Medium-Sized Languages

    Science.gov (United States)

    Soler, Josep

    2013-01-01

    Catalan and Estonian can be considered "medium-sized" languages with some key common features that allow us to analyze the evolution of the two cases comparatively. Firstly, other formerly hegemonic languages (Spanish and Russian, respectively) have historically minoritized them. Secondly, the political equilibrium has now changed in…

  16. 40 CFR 428.60 - Applicability; description of the medium-sized general molded, extruded, and fabricated rubber...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Applicability; description of the medium-sized general molded, extruded, and fabricated rubber plants subcategory. 428.60 Section 428.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS...

  17. 75 FR 5804 - Small and Medium-Sized Enterprises: U.S. and EU Export Activities, and Barriers and Opportunities...

    Science.gov (United States)

    2010-02-04

    ... affects SME business performance. The extent to which U.S. SMEs have global operations. How SMEs based in... Experienced by U.S. Firms and Small and Medium-Sized Enterprises: Characteristics and Performance AGENCY... individuals may obtain information on this matter by contacting the Commission's TDD terminal at 202-205-1810...

  18. 75 FR 65483 - Proposed Reissuance of General NPDES Permits (GP) for Alaskan Medium-Size Suction Dredging...

    Science.gov (United States)

    2010-10-25

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed Reissuance of General NPDES Permits (GP) for Alaskan Medium-Size Suction Dredging (Permit... general permit. SUMMARY: On October 7, 2010, the general permit regulating the activities of suction...

  19. Health and environmental effects of complex chemical mixtures: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    The Office of Health and Environmental Research (OHER) of the Department of Energy supports a broad long-term research program on human health and environmental effects from potential exposure to energy-related complex chemical mixtures. The program seeks basic mechanistic data on the effects of complex mixtures at the cellular, molecular, and whole animal levels to aid in predicting human health effects and seeks ecological data on biological and physical transformations in the mixtures, concentrations of the mixtures in various compartments of the environment, and potential routes for human exposure to these mixtures (e.g., food chain). On June 17-18, 1985, OHER held its First Annual Technical Meeting on the Complex Chemical Mixtures Program in Chicago, IL. The primary purpose of the meeting was to enable principal investigators to report the research status and accomplishments of ongoing complex chemical mixture studies supported by OHER. To help focus future research directions round table discussions were conducted.

  20. Method of evaluating the success of the small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Aleš Peprný

    2010-01-01

    Full Text Available At the time of increasing globalization and homogenization of the global markets, the development of information infrastructure technology and world market becomes accessible not only to large multinational companies but also for small and medium-sized enterprises (SMEs. This has resulted in increasing competition in the domestic market which domestic firms have to face. Therefore the pro­cess of internationalization of business is a step that allows businesses performing their activities in the domestic market to enter foreign markets and to exploit the opportunities and potential which these markets offer. The paper is focused on the draft of the method for quantification of the factors, which determine the success of the SMEs in foreign markets. In the proposed method the multidimensional assessment of indicators of success of SMEs in foreign markets are used, ie. not only the proportion of sales from exports is observed, but also the profitability of international activities in an absolute and in a relative rate. Other indicators of success are the satisfaction of the company management with international activities and the success of achieving defined targets for business activities in foreign markets. Evaluation is made up of both the objective and the subjective indicators of success. Among the objective indicators of success is included the intensity of international activities of SMEs, which is detected as the sum of revenues generated from international activities in relation to total sales company, the profitability of international activities, (ie. whether the foreign activities are profitable or not, and the relative profitability of international activities, where it is ascertained whether the foreign activities generate higher profit than the activities at the domestic market. The next subjective indicator of success is the success of objectives - it was found how many objectives related to operations in foreign markets has been

  1. Development and Evaluation of Algorithms to Improve Small- and Medium-Size Commercial Building Operations

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woohyun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Katipamula, Srinivas [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lutes, Robert G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Underhill, Ronald M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-10-31

    Small- and medium-sized (<100,000 sf) commercial buildings (SMBs) represent over 95% of the U.S. commercial building stock and consume over 60% of total site energy consumption. Many of these buildings use rudimentary controls that are mostly manual, with limited scheduling capability, no monitoring or failure management. Therefore, many of these buildings are operated inefficiently and consume excess energy. SMBs typically utilize packaged rooftop units (RTUs) that are controlled by an individual thermostat. There is increased urgency to improve the operating efficiency of existing commercial building stock in the U.S. for many reasons, chief among them is to mitigate the climate change impacts. Studies have shown that managing set points and schedules of the RTUs will result in up to 20% energy and cost savings. Another problem associated with RTUs is short-cycling, where an RTU goes through ON and OFF cycles too frequently. Excessive cycling can lead to excessive wear and lead to premature failure of the compressor or its components. The short cycling can result in a significantly decreased average efficiency (up to 10%), even if there are no physical failures in the equipment. Also, SMBs use a time-of-day scheduling is to start the RTUs before the building will be occupied and shut it off when unoccupied. Ensuring correct use of the zone set points and eliminating frequent cycling of RTUs thereby leading to persistent building operations can significantly increase the operational efficiency of the SMBs. A growing trend is to use low-cost control infrastructure that can enable scalable and cost-effective intelligent building operations. The work reported in this report describes three algorithms for detecting the zone set point temperature, RTU cycling rate and occupancy schedule detection that can be deployed on the low-cost infrastructure. These algorithms only require the zone temperature data for detection. The algorithms have been tested and validated using

  2. Improving HVAC operational efficiency in small-and medium-size commercial buildings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woohyun; Katipamula, Srinivas; Lutes, Robert

    2017-08-01

    Small- and medium-size (<100,000 sf) commercial buildings (SMBs) represent over 95% of the U.S. commercial building stock and consume over 60% of total site energy consumption. Many of these buildings use rudimentary controls that are mostly manual, with limited scheduling capability, no monitoring, or failure management. Therefore, many of these buildings are operated inefficiently and consume excess energy. SMBs typically use packaged rooftop units (RTUs) that are controlled by an individual thermostat. There is increased urgency to improve the operating efficiency of existing commercial building stock in the United States for many reasons, chief among them being to mitigate the climate change impacts. Studies have shown that managing set points and schedules of the RTUs will result in up to 20% energy and cost savings. Another problem associated with RTUs is short cycling, when an RTU goes through ON and OFF cycles too frequently. Excessive cycling can lead to excessive wear and to premature failure of the compressor or its components. Also, short cycling can result in a significantly decreased average efficiency (up to 10%), even if there are no physical failures in the equipment. Ensuring correct use of the zone set points and eliminating frequent cycling of RTUs thereby leading to persistent building operations can significantly increase the operational efficiency of the SMBs. A growing trend is to use low-cost control infrastructure that can enable scalable and cost-effective intelligent building operations. The work reported in this paper describes two algorithms for detecting the zone set point temperature and RTU cycling rate that can be deployed on the low-cost infrastructure. These algorithms only require the zone temperature data for detection. The algorithms have been tested and validated using field data from a number of RTUs from six buildings in different climate locations. Overall, the algorithms were successful in detecting the set points and ON

  3. The Small- and Medium-sized Enterprises Office (SME Office) at the European Medicines Agency.

    Science.gov (United States)

    Carr, M

    2010-01-01

    On 15 December 2005, the European Medicines Agency (EMEA) launched an "SME Office" to provide financial and administrative assistance to micro-, small- and medium-sized enterprises (SMEs), with the aim of promoting innovation and the development of new human and veterinary medicinal products by SMEs. According to current EU definition of an SME, companies with fewer than 250 employees, and an annual turnover of not more than 50 million euro or an annual balance sheet total of not more than 43 million euro, are eligible for assistance from the SME Office. Incentives available from the EMEA for SMEs, include: Administrative and procedural assistance from SME Office within the Agency; Fee reductions (90%) for scientific advice and inspections; Fee exemptions for certain administrative services (excluding parallel distribution); Deferral of the fee payable for an application for marketing authorisation or related inspection until after the grant of the marketing authorisation; Conditional fee exemption where scientific advice followed and marketing application is unsuccessful; Assistance with translations of the product information documents. At the end of May 2009, more than 380 companies from 21 countries across the European Economic Area (EEA) had SME status assigned by the EMEA. The large majority of companies are developing medicinal products for human use, 16 are veterinary companies, 15 companies are developing products for both human and veterinary use and 38 are regulatory consultants. Since the SME initiative started the Agency has processed more than 130 requests for scientific advice with fee reductions totalling of 6.9 million euro. Regulatory assistance has been provided to more than 170 companies and 12 companies have benefited from the SME translation service. Stakeholders have acknowledged the significant role the SME Office now plays as a service provider. In the period between January 2006 and June 2009, 34 applications for marketing authorization

  4. Ventilation in medium-sized and large boiler houses; Ventilation i medelstora och stoerre pannhus

    Energy Technology Data Exchange (ETDEWEB)

    Grotherus, Dan [AaF Installation AB, Oerebro (Sweden); Larsson, Tord [Oerebro Univ. (Sweden). Dept. of Technology

    2005-04-01

    The purpose of this report is to exemplify and clarify the need for ventilation in medium-sized and large boiler houses. We will furthermore present some recommendations, guidelines and advice for the design and construction of a boiler house ventilation system to the plant owners and suppliers of equipment. Boiler house ventilation can be performed in different ways using mechanical or natural ventilation. The solution to be chosen depends on the following factors: Working environment requirements and a necessity to control temperature and pressure in the boiler house; The design of the boiler plant and house; The need for combustion air; The investment expenditure as well as operation and maintenance costs. Mechanical ventilation should be chosen if the aim is a controllable 'climate'. The mechanical ventilation can be either centrally situated or distributed with many aggregates in the boiler house. Centrally situated ventilation equipment will give a higher accessibility and lower maintenance costs than a distributed ventilation system. If the boiler house is designed with natural ventilation the air and flue gas fans will be the only ones installed. In this case temperature and pressure inside the boiler house will be difficult to control. The design factor for the ventilation plant in a boiler house is in most cases the demand to cool the air inside the boiler house to approximately 45 deg C. This is the highest temperature allowed by the Occupational Safety and Health Act in a work environment where the boiler operator is working alone. The air flow which is required for the combustion is normally less than the air flow needed to cool the air in the boiler house. The supply air which is cooling the air inside the boiler house should be supplied on several different levels to attain an efficient cooling. If the combustion air is taken from the heated indoor air the boiler house will work as a heat reclaimer. The difference between outdoor and indoor

  5. NEW APPROACHES TO CUSTOMER BASE SEGMENTATION FOR SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Meleancă Raluca-Cristina

    2012-12-01

    Full Text Available The primary purpose of this paper is to explore current praxis and theory related to customer segmentation and to offer an approach which is best suited for small and medium sized enterprises. The proposed solution is the result of an exploratory research aiming to recognize the main variables which influence the practice of segmenting the customer base and to study the most applied alternatives available for all types of enterprises. The research has been performed by studying a large set of secondary data, scientific literature and case studies regarding smaller companies from the European Union. The result of the research consists in an original approach to customer base segmentation, which combines aspects belonging to different well spread practices and applies them to the specific needs of a small or medium company, which typically has limited marketing resources in general and targeted marketing resources in particular. The significance of the proposed customer base segmentation approach lies in the fact that, even though smaller enterprises are in most economies the greatest in number compared to large companies, most of the literature on targeting practices has focused primarily on big companies dealing with a very large clientele, while the case of the smaller companies has been to some extent unfairly neglected. Targeted marketing is becoming more and more important for all types of companies nowadays, as a result of technology advances which make targeted communication easier and less expensive than in the past and also due to the fact that broad-based media have decreased their impact over the years. For a very large proportion of smaller companies, directing their marketing budgets towards targeted campaigns is a clever initiative, as broad based approaches are in many cases less effective and much more expensive. Targeted marketing stratagems are generally related to high tech domains such as artificial intelligence, data mining

  6. Optimization as investment decision support in a Swedish medium-sized iron foundry - A move beyond traditional energy auditing

    Energy Technology Data Exchange (ETDEWEB)

    Thollander, Patrik; Mardan, Nawzad; Karlsson, Magnus [Department of Management and Engineering, Division of Energy Systems, Linkoeping University, SE 581 83 Linkoeping (Sweden)

    2009-04-15

    Due to increased globalisation, industries are facing greater competition that is pressing companies into decreasing their expenses in order to increase their profits. As regards Swedish industry, it has been faced with substantial increases in energy prices in recent years. Barriers to energy efficiency such as imperfect information inhibit investments in energy efficiency measures, energy audits being one means of reducing barriers and overcoming imperfect information. However, an evaluation of such energy audits in Sweden reveals that it is chiefly low-cost measures that are undertaken as a result of an audit. Moreover, these audits often tend to focus on support processes such as ventilation, lighting, air compressors etc., while measures impacting production processes are often not as extensively covered, which underlines the need for further support in addition to energy audits. Decision support is practised in a variety of different disciplines such as optimization and simulation and the aim of this paper is to explore whether investment decision support practices may be used successfully towards small and medium-sized manufacturers in Sweden when complex production-related investment decisions are taken. The optimization results from the different cases, involving a foundry's investment in a new melting unit, indicate that with no electricity price fluctuations over the day, the investment seems sound as it lowers the overall energy costs. However, with fluctuating electricity prices, there are no large differences in energy costs between the option of retaining the existing five melting furnaces at the foundry and investing in a twin furnace and removing the holding furnaces - which was the initial investment plan for the foundry in the study. It would not have been possible to achieve this outcome without the use of investment decision support such as MIND. One of the main conclusions in this paper is that investment decision support, when strategic

  7. IFRS IN THE SMALL AND MEDIUM-SIZED ENTITIES. DIFICULTIES AND OPPORTUNITIES OF THE IFRS FOR SMES

    OpenAIRE

    Moț Ioana

    2013-01-01

    IFRS IN THE SMALL AND MEDIUM-SIZED ENTITIES. DIFICULTIES AND OPPORTUNITIES OF THE IFRS FOR SMEs PhD Student Moț Ioana, West University of Timișoara, Faculty of Economics and Business Administration, România Doctoral programme - Accounting Scientific coordonator – Prof. Univ. Dr. Mateș Dorel Abstract: Over the years, the accounting have to meet a series of transformations and adaptations to the new trend by globalization, harmonisation and integration, trying to unfold t...

  8. VOLTTRON™: Tech-to-Market Best-Practices Guide for Small- and Medium-Sized Commercial Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Cort, Katherine A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Haack, Jereme N. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Katipamula, Srinivas [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Nicholls, Andrew K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-07-11

    VOLTTRON™ is an open-source distributed control and sensing platform developed by Pacific Northwest National Laboratory for the U.S. Department of Energy. It was developed to be used by the Office of Energy Efficiency and Renewable Energy to support transactive controls research and deployment activities. VOLTTRON is designed to be an overarching integration platform that could be used to bring together vendors, users, and developers and enable rapid application development and testing. The platform is designed to support modern control strategies, including the use of agent- and transaction-based controls. It also is designed to support the management of a wide range of applications, including heating, ventilation, and air-conditioning systems; electric vehicles; and distributed-energy and whole-building loads. This report was completed as part of the Building Technologies Office’s Technology-to-Market Initiative for VOLTTRON’s Market Validation and Business Case Development efforts. The report provides technology-to-market guidance and best practices related to VOLTTRON platform deployments and commercialization activities for use by entities serving small- and medium-sized commercial buildings. The report characterizes the platform ecosystem within the small- and medium-sized commercial building market and articulates the value proposition of VOLTTRON for three core participants in this ecosystem: 1) platform owners/adopters, 2) app developers, and 3) end-users. The report also identifies key market drivers and opportunities for open platform deployments in the small- and medium-sized commercial building market. Possible pathways to the market are described—laboratory testing to market adoption to commercialization. We also identify and address various technical and market barriers that could hinder deployment of VOLTTRON. Finally, we provide “best practice” tech-to-market guidance for building energy-related deployment efforts serving small- and

  9. e-Leadership through strategic alignment: an empirical study of small and medium sized enterprises in the digital age

    OpenAIRE

    Li, Weizi; Liu, Kecheng; Belitski, Maksim; Ghobadian, Abby; O'Regan, Nicolas

    2016-01-01

    Small and medium sized enterprises (SMEs) play an important role in the European economy. A critical challenge faced by SME leaders, as a consequence of the continuing digital technology revolution, is how to optimally align business strategy with digital technology to fully leverage the potential offered by these technologies in pursuit of longevity and growth. There is a paucity of empirical research examining how e-leadership in SMEs drives successful alignment between business strategy an...

  10. Environmental education for small- and medium-sized enterprises: methodology and e-learning experience in the Valencian region.

    Science.gov (United States)

    Cloquell-Ballester, Vicente-Agustín; Monterde-Díaz, Rafael; Cloquell-Ballester, Víctor-Andrés; Torres-Sibille, Ana Del Carmen

    2008-05-01

    The last decades have shown an increasing social demand for environmental awareness, which firms are inevitably required to adapt to. More and more, small- and medium-sized enterprises (SMEs) are finding it necessary to train their staff in environmental issues if they wish to survive in a market where it is no longer sufficient to excel in price competitiveness exclusively, but where quality, service and environmental standards also play an important role.

  11. Procurement in Property and Construction - A review of practises under taken by a medium size contractor in Ireland

    OpenAIRE

    Mitchell, Charles

    2015-01-01

    3B Contracting Limited is a privately owned building and civil engineering firm on the east coast of Ireland. The company works predominately within the east Leinster region. The company falls into the category of being a small to medium size contracting company. The procurement function is carried out by a number of small departments. Procurement is a key function for securing value for money and ensuring the successful continuation of the company. Most projects tendered are done so us...

  12. An Empirical Study of IT Innovation Adoption Among Small and Medium Sized Enterprises in Klang Valley, Malaysia

    OpenAIRE

    Sedigheh Moghavvemi; Noor A. Mohd Salleh; Wenjie Zhao; Fatemeh Hakimian

    2011-01-01

    Purpose—The purpose of this research is to use and validate the Entrepreneurial Event model as a base model to investigate SME owners’ perception toward IT innovation adoption and use. This paper also attempts to investigate the key determinants of the adoption of IT innovation among small and medium sized enterprises in Kuala Lumpur, Malaysia. This study revised and validated the Entrepreneurial Event Model in a new context and tried to examine the effect of perceived desirability, propensit...

  13. An empirical study on the critical success factors of small to medium sized projects in a South African mining company

    OpenAIRE

    Du Randt, Francois Jean; Van Waveren, Cornelis Cristo; Kai-Ying Chan

    2014-01-01

    Projects that fail, for whatever reason, can impact negatively on society, organisations, and other stakeholders. A number of researchers have identified various critical success factors (CSFs) that can influence the outcome and success of a project. This research therefore aims to determine the CSFs that influence various success measures of small- to medium-sized projects at a South African mining company, Exxaro Resources’ Grootegeluk Coal Mine. Other objectives of this research include de...

  14. Distinguishing between the bone fragments of medium-sized mammals and children. A histological identification method for archaeology.

    Science.gov (United States)

    Cuijpers, Saddha A G F M

    2009-06-01

    In archaeology, it is not always possible to identify bone fragments. A novel approach was chosen to assess the potential of histology as an identification tool. Instead of studying a few bones of different categories from many species, this study concentrated on the diaphyses of long bones in four species of comparable size which are relevant to archaeology; young humans, pigs, sheep and goats, to broaden the insight into variations in diaphyseal bone structure within and between these species. A general difference in the primary bone structure was found between children older than one year and the three medium-sized mammals, namely lamellar vs. fibro-lamellar primary bone. Although, the diaphyseal bone structure of children below the age of one year also showed (developing) fibro-lamellar bone, its composition was distinctive from the medium-sized mammals. A difference in the secondary bone structure was also observed. Connecting (Volkmann's) canals, giving the secondary bone a reticular aspect, were seen in the medium-sized mammals but not in the young human long bones. To confirm the validity and applicability of these observed histological differences, a blind test was conducted on 14 diaphyseal fragments of identified long bones from archaeological sites. The results were very promising. All the bone fragments were correctly attributed using the difference in primary bone structure, even when the bone was severely degraded.

  15. Influence of complexing agent (Na 2 EDTA) on chemical bath ...

    African Journals Online (AJOL)

    The quality of thin film is influenced by the presence of complexing agents such as Na2EDTA. The Cu4SnS4 thin films were deposited onto indium tin oxide glass substrate by chemical bath deposition method. The structural, morphological and optical properties of the deposited films have been studied using X-ray ...

  16. INFLUENCE OF COMPLEXING AGENT (Na2EDTA) ON CHEMICAL ...

    African Journals Online (AJOL)

    Preferred Customer

    ABSTRACT. The quality of thin film is influenced by the presence of complexing agents such as Na2EDTA. The Cu4SnS4 thin films were deposited onto indium tin oxide glass substrate by chemical bath deposition method. The structural, morphological and optical properties of the deposited films have been studied using X- ...

  17. [Company integration management in small and medium-sized companies. Legal requirements and prerequisites for successful implementation].

    Science.gov (United States)

    Ramm, D; Mahnke, C; Tauscher, A; Welti, F; Seider, H; Shafaei, R

    2012-01-01

    The article is based on the results of the project “Company integration management in small and medium-sized companies. Legal requirements and prerequisites for a successful implementation” (01 January 2009-31 August 2010). Since 2004 all employers have been legally bound to offer company integration management (BEM, Betriebliches Eingliederungsmanagement) for all employees who have been incapacitated for work for more than 6 weeks within a year (Section 84 SGB IX, Book 9 of the German Social Code). Objective of this law is to ensure ongoing employment. The aim of the study was to investigate the requirements companies, rehabilitation centres and services as well as social insurance institutions are faced with according to Section 84 SGB IX. Prerequisites for an effective implementation of BEM in small and medium-sized enterprises were analyzed. Protocol-based interviews with experts were adopted. A total of 38 interviews with experts were carried out. The experts interviewed were either willing to give information by interest (concernment) or were named by law as an initiator or co-operator in the process of integration. A substantial literature research was performed in advance of the interviews. The awareness level of BEM is still very low even 7 years after its introduction. Small and medium-sized enterprises do not have any significant experiential knowledge of long-term incapacity for work and, hence, about BEM. Due to a lack of workers representation in many small and medium companies, management does not receive initiatives or support in implementation of BEM from employees' side. Employers prefer a central contact point providing them with the information and help needed, the common service units, however, being widely unknown in this context. Cost comparisons suggest that a company integration management might be more cost-effective than dismissing employees who are incapacitated for some fields of work. These findings might even hold true for small

  18. Oncoplastic surgery combining abdominal advancement flaps with volume displacement techniques to breast-conserving surgery for small- to medium-sized breasts.

    Science.gov (United States)

    Ogawa, Tomoko; Hanamura, Noriko

    2016-11-01

    An abdominal advancement flap (AAF) is a flap that pulls the elevated abdominal skin up, creating the shape of the inferior portion of the breast by making a neo-inframammary fold. We used an AAF combined with volume displacement techniques to fill the defect left after breast-conserving surgery (BCS). Forty-one small- to medium-sized breast patients whose resection area included the lower portion of the breast underwent this procedure from October 2010 to December 2014. We evaluated efficacy of this procedure. The excision volume ranged from 10 to 35 %. Complications after surgery were observed in two patients (partial necrosis of the nipple-areola complex and partial necrosis of the breast skin in one patient each). There was no fat necrosis of the flap in any of the patients. The cosmetic results were found to be excellent in 7 cases, good in 23, fair in 9 and poor in 2. In 11 cases with an unacceptable outcome, 9 cases were in the inner portion. In patients with the tumor in the inner portion, the proportion of unacceptable cases was 50 %. In the cases other than the inner portion, the proportion of unacceptable cases was 8.7 % (p < 0.01). In the cases with larger breasts, unacceptable cases were more frequently observed (p < 0.05). We believe that an AAF combined with volume displacement techniques may be useful following BCS in the lower portion of a small- to medium-sized breast, except in cases where the tumors is located in the inner potion.

  19. Discriminating between medium-sized Tridactyl Trackmakers: tracking Ornithopod tracks in the base of the Cretaceous (Berriasian, Spain.

    Directory of Open Access Journals (Sweden)

    Diego Castanera

    Full Text Available BACKGROUND: Recent work on the Jurassic-Cretaceous transition of the Iberian Range (Spain has opened a new window onto the interpretation of the trackmakers of some medium-sized tridactyl tracks. The ichnotaxon Therangospodus oncalensis has been described in the Huérteles Formation (Berriasian and is one of the classical tracks from the area assigned to medium-sized theropods. METHODOLOGY/PRINCIPAL FINDINGS: A review of the type locality of Therangospodus oncalensis (Fuentesalvo tracksite and other tracksites from the Huérteles Formation (Berriasian has yielded new information on the morphology, gait and trackmaker identity of the aforementioned ichnospecies. The new data suggest that the trackmaker is an ornithopod rather than a theropod on the basis of the length/width ratio, the anterior triangle length-width ratio, the short steps, the round to quadrangular heel pad impression and the probable manus impressions. CONCLUSIONS/SIGNIFICANCE: T. oncalensis shows similarities with various tracks from the Berriasian of Europe assigned to Iguanodontipus. The ichnotaxonomical status of this ichnospecies is here considered as Iguanodontipus? oncalensis due to the current state of knowledge of the ichnotaxonomy of medium-sized ornithopod tracks. This reassessment of I? oncalensis also has two significant implications for the palaeoecology of the faunas during the deposition of the Huérteles Formation: 1- the high number and percentage of theropod tracks would be lower than previous papers have suggested. 2- the gregarious behaviour described in the type locality (Fuentesalvo would be among ornithopods instead of theropods.

  20. An integrated approach for developing a technology strategy framework for small- to medium-sized furniture manufacturers to improve competitiveness

    Directory of Open Access Journals (Sweden)

    Lourens, A.S.

    2013-05-01

    Full Text Available Low-technology firms, such as those found within the furniture manufacturing industry, have no framework or methodology to guide them successfully to acquire and integrate technology that enables them to operate more competitively. The aim of this article is to illustrate the development of a technology strategy framework for small- to medium-sized furniture manufacturers to assist them to improve their competitiveness. More specifically, this article presents an integrated technology strategy framework that enables management to integrate their business strategy with their technology requirements successfully, thus improving competitiveness.

  1. Efficiency of Electrical Stunning by Electronarcosis: Current Situation and Perspective of Improvement in a Medium-Size Processing Plant

    Directory of Open Access Journals (Sweden)

    RL Barbosa

    Full Text Available ABSTRACT The objective of this study was to evaluate the efficiency of electrical stunning by electronarcosis in a medium-size poultry processing plant located in southern Brazil. The current measurement of this type of stunning is presented, and then improvements to this method are proposed. Data were collected for 90 days. A quality indicator was proposed: the Stunning Severity Index (SSI, which includes elements of Statistical Process Control (SPC using a p-chart (proportion chart and measures. This index comprises the variables "wing-flapping," "arched head," and "rhythmic breathing." Using the proposed index, 5% of the birds, on average, presented inefficient stunning symptoms.

  2. THE RELATIONSHIP BETWEEN TANGIBLE ASSETS AND CAPITAL STRUCTURE OF SMALL AND MEDIUM-SIZED COMPANIES IN CROATIA

    Directory of Open Access Journals (Sweden)

    Martina Harc

    2015-07-01

    Full Text Available The asset structure of companies should matter for financing decisions. Small and medium-sized companies in Croatia may use tangible assets as collateral, either providing more access to creditors or as a guarantee in case of bankruptcy. The aim of this paper is to investigate the relationship between tangible assets and the capital structure of Croatian small and medium-sized enterprises. Most previous studies have shown various relationships between tangible assets and leverage. This study has been conducted on a sample of 500 Croatian SMEs for the period between 2005 and 2010. The data used for the empirical analysis were taken from companies’ annual reports. The Pearson Correlation Coefficient is applied in order to examine the relationship between tangible assets and leverage measures. The results of this research indicate that tangible assets are differently correlated with short-term and long-term leverage. The relationship between tangible assets and short-term leverage is negative and statistically significant in all observed years. The relationship between tangible assets and long-term leverage is positive in all observed years and statistically significant. The results show that small and medium-sized companies use their collateral to attract long-term debt, which means that small and medium-sized companies use lower costs and the interest rate of long-term debt in relation to short-term debt. These findings correspond with the maturity matching principle, according to which long-term assets are financed with long-term financing and short-term assets are financed with short-term funds. These results suggest that tangible assets have a positive impact on the long-term debt of Croatian SMEs because tangible assets constitute a positive signal to the financial institutions, which can request the selling of these assets in case of bankruptcy. These findings are consistent with the trade-off theory which predicts a positive relation

  3. Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles.

    Science.gov (United States)

    Dongamanti, Ashok; Aamate, Vikas Kumar; Devulapally, Mohan Gandhi; Gundu, Srinivas; Kotni, Meena Kumari; Manga, Vijjulatha; Balasubramanian, Sridhar; Ernala, Prasad

    2015-02-15

    A convenient approach for the synthesis of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized heterocyclic rings (eight-, nine-, ten- and eleven-membered rings) containing two oxygen atoms from flavonols through alkylation using different dibromoalkanes was described. The synthesized compounds were established based on the spectral data and X-ray crystal structure for 6c. The synthesized compounds were evaluated for their in vitro antimicrobial activity. Docking studies were carried out for most active two compounds 6f and 6i. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. PyRETIS: A well-done, medium-sized python library for rare events.

    Science.gov (United States)

    Lervik, Anders; Riccardi, Enrico; van Erp, Titus S

    2017-10-30

    Transition path sampling techniques are becoming common approaches in the study of rare events at the molecular scale. More efficient methods, such as transition interface sampling (TIS) and replica exchange transition interface sampling (RETIS), allow the investigation of rare events, for example, chemical reactions and structural/morphological transitions, in a reasonable computational time. Here, we present PyRETIS, a Python library for performing TIS and RETIS simulations. PyRETIS directs molecular dynamics (MD) simulations in order to sample rare events with unbiased dynamics. PyRETIS is designed to be easily interfaced with any molecular simulation package and in the present release, it has been interfaced with GROMACS and CP2K, for classical and ab initio MD simulations, respectively. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  5. MAP SUPPORT FOR ENVIRONMENTAL PLANNING OF A MEDIUM-SIZE INDUSTRIAL CITY

    Directory of Open Access Journals (Sweden)

    L. A. Matyushkina

    2016-01-01

    Full Text Available The paper presents a set of thematic maps reflecting the current geo-ecological urban area conditions of Birobidzhan, an administrative and industrial center of the Jewish Autonomous Oblast. The maps shows landscape-functional complexes of the city; main types of natural and anthropogenic soils; urban area zoning by the degree of disturbance of soil ecological functions; levels of contamination of soils, dendroflora and snow with heavy metals. Component-based maps help improving environmental urban planning including ecological and functional city zoning and designing the ecological carcass with all its structural elements.

  6. How to Improve Small and Medium-Sized Enterprises Profitability by Practicing an Efficient Human Resources Management

    Directory of Open Access Journals (Sweden)

    Antonio GARCÍA SÁNCHEZ

    2011-01-01

    Full Text Available In The European Union’s country members, small and medium-sized enterprises (SMEs play an essential role in economic life, having special features that make adaptation process to the contemporary economy easier. Small and medium sized enterprises (SMEs are the most dynamic and vital factor of progress in the contemporary society, main generator of economic performance and substance in any country, employment opportunity provider for most of population, major contributor to the national budget, and engine to improve the living standard of the population. SMEs represent 99% from all enterprises, drawing up the main human resources aglomeration. In the contemporary economic context, SMEs should act as learning entities, by developing the most important resources they own: the human resources. Human resource development (HRD has gained a permanent role within SMEs, agencies and nations, increasingly not only as an academic discipline, but as a central theme in development area. Being a combination of training and education, in a broad context of adequate human resource policies, HRD ensures the continual improvement and growth of both individual and organization.

  7. A qualitative study of pandemic influenza preparedness among small and medium-sized businesses in New York City.

    Science.gov (United States)

    Burton, Deron C; Confield, Evan; Gasner, Mary Rose; Weisfuse, Isaac

    2011-10-01

    Small businesses need to engage in continuity planning to assure delivery of goods and services and to sustain the economy during an influenza pandemic. This is especially true in New York City, where 98 per cent of businesses have fewer than 100 employees. It was an objective therefore, to determine pandemic influenza business continuity practices and strategies suitable for small and medium-sized NYC businesses. The study design used focus groups, and the participants were owners and managers of businesses with fewer than 500 employees in New York City. The main outcome measures looked for were the degree of pandemic preparedness, and the feasibility of currently proposed business continuity strategies. Most participants reported that their businesses had no pandemic influenza plan. Agreement with feasibility of specific business continuity strategies was influenced by the type of business represented, cost of the strategy, and business size. It was concluded that recommendations for pandemic-related business continuity plans for small and medium-sized businesses should be tailored to the type and size of business and should highlight the broad utility of the proposed strategies to address a range of business stressors.

  8. Proximal Occlusion of Medium-Sized Vessels with the Penumbra Occlusion Device: A Study of Safety and Efficacy.

    Science.gov (United States)

    Jambon, E; Petitpierre, F; Brizzi, V; Dubuisson, V; Le Bras, Y; Grenier, N; Cornelis, F

    2017-02-01

    To retrospectively investigate the safety and efficacy of hybrid proximal coiling of various medium-sized vessels (4 to 8 mm) using the Penumbra Occlusion Device (POD). From October 2014 to February 2016, 37 proximal embolizations were performed with PODs in 36 patients (mean age: 50.8, range: 10-86; 29 male, 7 female). Vessel occlusions were achieved under fluoroscopic guidance using a 2.7 French microcatheter. Among the 36 vessels targeted, 16 were splenic arteries, 11 renal arteries, 4 mesenteric arteries, 3 arteriovenous fistulae, 1 iliac artery, and 1 gonadal vein. Intermittent follow-up angiography was performed to assess the flow for final occlusion. Outcomes and complications were assessed by clinical and/or imaging follow-up. To produce proximal occlusion of the intended vessels, the POD was used alone in 19 embolizations (51.4 %). In 12 procedures (32.4 %), POD was used as a coil constrainer to secure the coil construct. In 6 procedures (16.2 %), additional embolic devices were used to achieve vessel occlusion after initial POD deployment. After a mean follow-up of 3.2 months, no POD migration was observed but two complications occurred (5.4 %): one post embolic syndrome and one extensive infarction with splenic abscess. The POD system allows safe and effective proximal embolization of medium-sized vessels in a variety of clinical settings.

  9. Proximal Occlusion of Medium-Sized Vessels with the Penumbra Occlusion Device: A Study of Safety and Efficacy

    Energy Technology Data Exchange (ETDEWEB)

    Jambon, E.; Petitpierre, F. [Pellegrin Hospital, Department of Radiology (France); Brizzi, V.; Dubuisson, V. [Pellegrin Hospital, Department of Surgery (France); Bras, Y. Le; Grenier, N.; Cornelis, F., E-mail: cornelisfrancois@gmail.com [Pellegrin Hospital, Department of Radiology (France)

    2017-02-15

    PurposeTo retrospectively investigate the safety and efficacy of hybrid proximal coiling of various medium-sized vessels (4 to 8 mm) using the Penumbra Occlusion Device (POD).Materials and MethodsFrom October 2014 to February 2016, 37 proximal embolizations were performed with PODs in 36 patients (mean age: 50.8, range: 10–86; 29 male, 7 female). Vessel occlusions were achieved under fluoroscopic guidance using a 2.7 French microcatheter. Among the 36 vessels targeted, 16 were splenic arteries, 11 renal arteries, 4 mesenteric arteries, 3 arteriovenous fistulae, 1 iliac artery, and 1 gonadal vein. Intermittent follow-up angiography was performed to assess the flow for final occlusion. Outcomes and complications were assessed by clinical and/or imaging follow-up.ResultsTo produce proximal occlusion of the intended vessels, the POD was used alone in 19 embolizations (51.4 %). In 12 procedures (32.4 %), POD was used as a coil constrainer to secure the coil construct. In 6 procedures (16.2 %), additional embolic devices were used to achieve vessel occlusion after initial POD deployment. After a mean follow-up of 3.2 months, no POD migration was observed but two complications occurred (5.4 %): one post embolic syndrome and one extensive infarction with splenic abscess.ConclusionThe POD system allows safe and effective proximal embolization of medium-sized vessels in a variety of clinical settings.

  10. Theoretical Aspects And Development Of The Mechanism For Risk Management In Small- And Medium-Sized Business

    Directory of Open Access Journals (Sweden)

    Lezgovko Aleksandra

    2016-06-01

    Full Text Available Modern scientific research in the field of risk management is mainly devoted to general questions of the market theory of risk management, including qualitative risk analysis, protection of the rights of property owners and the study of the problems of selection of the best strategies for profitable market investments. The development of risk management mechanisms for small- and medium-sized businesses in Lithuania compared to other European markets is happening too slowly. The situation is aggravated by unstable situation of the field itself, corrupted officials and the lack of advanced control strategies for internal and external risk management in organisations. All these factors confirm the need to develop new management tools in the field of risk management at such enterprises. The aim of this article is to develop the mechanism of risk management of small and medium-sized businesses and justify it scientifically. The methodology of the research is based on the principles of objectivity using methods of comparative, logical, mathematical statistics and system-structural analysis.

  11. Comparison of the selected conditions of the small and medium-sized enterprise in the Czech Republic and EU

    Directory of Open Access Journals (Sweden)

    Helena Chládková

    2009-01-01

    Full Text Available Companies classified as small and medium-sized enterprises (SMEs account for a large proportion of Europe’s economic and professional activity. In practice, 99 % of business in the European Union are SMEs, and they provide two–thirds of all private sector jobs. So small firms are, in fact, the real ­giants of the European economy. Micro–business dominate employment in countries such as Italy 47 % and Poland 41 %, whilst the share of large enterprises in total employment in the United Kingdom is just 46 %.During the recent period of time there have been many researchers from the FBE MUAF in Brno, who focused on the analysis of the small and medium-sized enterprise, e.g. Nerudová (2006; Nerudová and Bohušová (2006; Kubíčková and Presová (2006; Zrůst and Pyšný (2008; Živělová and Zichová (2002.This paper is the part of the Research proposal MSM 6215648904 being solved at the FBE MUAF in Brno.

  12. An empirical study on the critical success factors of small to medium sized projects in a South African mining company

    Directory of Open Access Journals (Sweden)

    Du Randt, Francois Jean

    2014-08-01

    Full Text Available Projects that fail, for whatever reason, can impact negatively on society, organisations, and other stakeholders. A number of researchers have identified various critical success factors (CSFs that can influence the outcome and success of a project. This research therefore aims to determine the CSFs that influence various success measures of small- to medium-sized projects at a South African mining company, Exxaro Resources’ Grootegeluk Coal Mine. Other objectives of this research include determining the extent of the impacts of these CSFs on the different success measures of a project. The investigation suggests that there are correlations among CSFs, and that certain factors impact the outcome of projects far more than others. This research finds that the single most important CSF for small- to medium-sized projects is the selection of a competent project manager. The competent project manager is characterised by a group of interrelated CSF factors: good leadership, commitment, and learning from past experiences. Based on the research results, other CSFs are discussed and explored in order for recommendations to be made on how this mining company, and possibly other organisations, can achieve greater project success.

  13. Complex gene-chemical interactions: hepatic uroporphyria as a paradigm.

    Science.gov (United States)

    Smith, Andrew G; Elder, George H

    2010-04-19

    Many toxicological disorders, in common with numerous human diseases, are probably the consequence of multigene interactions with a variety of chemical and physiological factors. The importance of genetic factors may not be obvious initially from association studies because of their complexity and variable penetrance. The human disease, porphyria cutanea tarda (PCT), is a skin disease caused by the photosensitizing action of porphyrins arising secondary to the decreased activity of an enzyme of heme biosynthesis, uroporphyrinogen decarboxylase (UROD), in the liver. It is triggered by idiosyncratic hepatic interaction between genetic factors and chemicals such as alcohol, estrogenic drugs, and polyhalogenated aromatics. PCT and its animal models are known collectively as the hepatic uroporphyrias. There is strong evidence for the participation of iron in the pathogenesis of these conditions. Mouse models have been used to explore the relative importance of a variety of agents such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), alcohol, and iron in the development of uroporphyria and to elucidate the mechanism of the depression of hepatic UROD activity. Mutations of the UROD and hemochromatosis (HFE) genes are genetic factors in some PCT patients which can be mimicked in mice heterozygous for the Hfe and Urod null genes. Association studies of uroporphyria induced by TCDD or hexachlorobenzene with DNA markers in mouse intercrosses have shown the participation of other, unknown, genetic factors in addition to the strong influence of the Ahr gene. The pathogenesis of hepatic uroporphyrias exemplifies the complexity of the interactions between chemical and genetic factors that can contribute to the hepatotoxicity of chemicals.

  14. How Banks Deal with the Financial Information of Medium Sized Firms in the Credit Assessment Process : A study of banks in Pakistan

    OpenAIRE

    Chohan, Kashif Ali; Rahaman, K.M. Abdur

    2011-01-01

    Financial information of a firm helps the users of the financial information to understand the financial standing of the firm. Banks as lenders to Medium Sized firms use the financial information in the credit assessment process. The availability and quality of the financial information depends on the information environment of the country. We have conducted a quantitative study where we examined 80 loan applications of the Medium Sized firms to the Big4 private banks inPakistan. We collected...

  15. Design Support by Improving Method Transfer - A Procedural Model and Guidelines for Strategic Product Planning in Small and Medium-sized Enterprises

    OpenAIRE

    Braun, T.;Gausemeier, J.;Lindemann, U.;Orlik, L.;Vienenkötter, A.

    2017-01-01

    Efficient and effective strategic product planning gets more and more important for small and medium-sized enterprises (SMEs) to ensure sustainable success in business. Although numerous methods in the field of strategic product planning exist, especially in small and medium-sized enterprises the use of these methods isn’t very established up to now. Usually strategic planning is not institutionalized in SMEs and resources for strategic planning are limited. Furthermore, a lack of experience ...

  16. Small And Medium-Sized Business Development In Regions: Establishment Of Priority Directions By The Example Of Sverdlovsk Region

    Directory of Open Access Journals (Sweden)

    Dmitry Yevgenyevich Tolmachev

    2015-03-01

    Full Text Available The paper presents the research of current small and medium-sized business development in Sverdlovsk region. It includes analysis of enterprise development statistics, Russian and international experience, sociological survey of entrepreneurs’ satisfaction of doing business conditions in Sverdlovsk region. The aim of the research was to develop proposals for business support system development in the long run for inclusion in the SME Development Strategy in Sverdlovsk region up to 2030. As a result, a set of strategic SME development directions was formulated. It includes measures aimed at business problems solving through the development of SME support tools and at addressing institutional problems of business support. The paper includes proposals for improvement of regional support system and implementation the priority SME development direction

  17. The triple helix frame for Small and Medium-sized Enterprises for innovation and development of offshore wind energy

    DEFF Research Database (Denmark)

    Brink, Tove; Madsen, Svend Ole

    2016-01-01

    This research reveals how small- and medium-sized enterprises (SMEs) can enable innovation and contribute to a reduction in the levelized cost of energy (LCOE) in offshore wind farms. The research provides findings from a longitudinal qualitative study of 10 SMEs for the understanding of the impact...... from integrating SMEs in a triple helix context. The triple helix approach with government, university and industry participants typically include larger organisations. The research indicates that SMEs could join the triple helix and both contribute and receive benefit from their presence. The findings...... show that SMEs need access to market and industry stakeholders to understand, learn and select among business innovation opportunities. Universities, governmental bodies and industries can create a knowledge space for organisational reciprocal learning between SMEs and larger enterprises to enable...

  18. Innovation incubators – entities of support of small and medium-sized enterprises’ competitiveness in the Modern economy

    Directory of Open Access Journals (Sweden)

    Maier Lidia

    2013-02-01

    Full Text Available Innovation incubators are entities of the infrastructure network of support of small and medium-sized enterprises. At the stage of SMEs’ maximum vulnerability, they improve the survival of innovative businesses through the range of services and facilities provided. They are designed to mitigate the problems faced by SMEs, which develop and implement innovations, ensuring sustainability and competitiveness. Along with promoting the entrepreneurial spirit, innovation incubators play an essential role in promoting knowledge and innovation transfer, introduction of the research results into economic circuit, creating links between businesses, universities, research institutions, etc., links between people, talents and resources.In this article, we will focus on innovation incubators, their role in the development of SMEs in the world and in the Republic of Moldova, making an accent in the creation and development of the country's first Innovation Incubator „Inovatorul”.

  19. THE STRATEGIC RELEVANCE OF TECHNOLOGY-RELATED VARIABLES TO THE COMPETITIVENESS OF SMALL - TO MEDIUM-SIZED FURNITURE MANUFACTURERS

    Directory of Open Access Journals (Sweden)

    Lourens, A. S.

    2012-11-01

    Full Text Available SMMEs can make a critical and positive economic contribution to South Africa, and small- to medium-sized furniture manufacturers (SM/FMs have the potential to contribute to economic growth, job creation, and GDP. However, the furniture industry has not stayed abreast of technological advances. To survive in an environment of increasing competition and imports, competitive strategies must be devised. One such strategy is for technology adoption and implementation that can provide solutions for the furniture industry to improve speed, quality, variety, flexibility, and productivity, resulting in improved competitiveness. However, the adoption of technology means that its acquisition and application must be managed strategically, as the use of technology involves far more than simply taking it into account during the business-plan

  20. The influence of family-related factors on the succession process in small and medium-sized family businesses

    Directory of Open Access Journals (Sweden)

    E Venter

    2014-07-01

    Full Text Available In this study family-related factors that can influence the succession process in small and medium-sized family businesses are empirically investigated.  The dependent variable in this study is measured by two underlying dimensions, namely satisfaction with the process and continued profitability of the business.  The empirical results indicate that the family-related factors that influence both the aforementioned dimensions are the mutual acceptance of roles, the relationship between the owner-manager and successor, and family harmony.  The continued profitability of the business is also influenced by the agreement to continue the business. The existence of family harmony in itself influences the relationship between the owner-manager and successor, the agreement to continue the business, as well as the mutual acceptance of roles.  The managerial implications of these empirical findings are discussed and recommendations offered.

  1. The triple helix frame for Small and Medium-sized Enterprises for innovation and development of offshore wind energy

    DEFF Research Database (Denmark)

    Brink, Tove; Madsen, Svend Ole

    2016-01-01

    This research reveals how small- and medium-sized enterprises (SMEs) can enable innovation and contribute to a reduction in the levelized cost of energy (LCOE) in offshore wind farms. The research provides findings from a longitudinal qualitative study of 10 SMEs for the understanding of the impact...... show that SMEs need access to market and industry stakeholders to understand, learn and select among business innovation opportunities. Universities, governmental bodies and industries can create a knowledge space for organisational reciprocal learning between SMEs and larger enterprises to enable...... innovation for the reduction of the LCOE in the wind farm industry. This knowledge space also provides important insight and understanding for the governmental and university helices for active contribution to offshore wind energy. The governmental policy impact stresses the need for a more strategic long...

  2. WILLINGNESS TO PAY FOR IMPLEMENTING HACCP SYSTEMS IN CHINA’S SMALL AND MEDIUM-SIZED FOOD ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Shaosheng Jin

    2016-04-01

    Full Text Available In China, a large number of small and medium-sized food enterprises (food SMEs rarely adopt the hazard analysis and critical control points (HACCP system, which results in a low product quality. Some local governments have encouraged food SMEs to implement HACCP systems through financial subsidies, but because of an incomplete understanding of the willingness to pay (WTP for implementing HACCP systems in food SMEs, relevant policies have not enhanced the adoption rate of HACCP systems. Based on our questionnaire survey data of 132 food SMEs in China's Henan, Guangdong, and Zhejiang provinces, this study estimates Chinese food SMEs' WTP for implementing HACCP systems by a double bounded dichotomous choice contingent valuation method (CVM. According to the estimated results, the WTP for implementing HACCP systems under the log-logistic model is approximately 115,714 Chinese RMB (113,149 Chinese RMB for the log-normal model.

  3. Aggregate Production Planning, Casestudy in a Medium-sized Industry of the Rubber Production Line in Ecuador.

    Science.gov (United States)

    Rosero-Mantilla, César; Sánchez-Sailema, Mayra; Sánchez-Rosero, Carlos; Galleguillos-Pozo, Rosa

    2017-06-01

    This research aims to improve the productivity in the rubber line of a medium-sized industry by increasing the production capacities through the use of the Aggregate Production Planning model. For this purpose an analysis of the production processes of the line was made and the aggregate plan was defined evaluating two strategies: Exact Production Plan (Zero Inventory) and Constant Workforce Plan (Vary Inventory) by studying the costs of both inventory maintenance and workforce. It was also determined how the installed capacity was used with the standards of the rubber line and measures for decreasing production costs were proposed. It was proven that only 70% of the plant capacity was being used so it could be possible to produce more units and to obtain a bigger market for the products of this line.+

  4. Small and medium-sized enterprises in the export-oriented strategy of Ukraine’s development

    Directory of Open Access Journals (Sweden)

    Yuliya Yevdokymova

    2007-03-01

    Full Text Available The article examines the role of small and medium-sized enterprises (SMEs in the economic development of Ukraine, as it enters the world arena through its export potential. The author accentuates the diverse methods, ways and areas of economic policy for improving the export performance of SMEs. In particular, attention is centered on the support of SMEs by governments, international organizations and associations of entrepreneurs-exporters. In the opinion of the author, it is imperative to analyze the global experience in improving and stimulating SME exports not only in the economically developed countries, but also in those that are at such a political and socioeconomic stage of development as Ukraine is today. The author lists the policy areas for improving SME exports and their essence and outlines the prospects for their further development.

  5. [Cultivation strategy and path analysis on big brand Chinese medicine for small and medium-sized enterprises].

    Science.gov (United States)

    Wang, Yong-Yan; Yang, Hong-Jun

    2014-03-01

    Small and medium-sized enterprises (SMEs) are important components in Chinese medicine industry. However, the lack of big brand is becoming an urgent problem which is critical to the survival of SMEs. This article discusses the concept and traits of Chinese medicine of big brand, from clinical, scientific and market value three aspects. Guided by market value, highlighting clinical value, aiming at the scientific value improvement of big brand cultivation, we put forward the key points in cultivation, aiming at obtaining branded Chinese medicine with widely recognized efficacy, good quality control system and mechanism well explained and meanwhile which can bring innovation improvement to theory of Chinese medicine. According to the characters of SMEs, we hold a view that to build multidisciplinary research union could be considered as basic path, and then, from top-level design, skill upgrading and application three stages to probe the implementation strategy.

  6. Fuzzy model of relationship among economic performance, competitiveness and business ethics of small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Nina Bočková

    2012-01-01

    Full Text Available The objective of this article is to study the relations among financial indicators, competitiveness and business ethics of comparable small and medium-sized enterprises. A sample of 59 SMEs from the South Moravia region was chosen. All selected companies either produce or service electronics. This research is based on the application of scientific analysis, synthesis, induction, fuzzy logic and modeling. Information for this research was obtained from secondary information sources – Amadeus database, accounting statements and information from the register of companies. Each company is described by a set of 10 variables. Fuzzy sets and reasoning are ideal tools to cope with vague, ill-structured and uncertain scenarios which can be found frequently in business and economics. This is the main reason why fuzzy logic was used in this research. The paper is self-explanatory and no a prior knowledge of fuzzy reasoning is required.

  7. Managerial competencies among first-line newsroom managers at small to medium-sized mainstream media enterprises in South Africa

    Directory of Open Access Journals (Sweden)

    Elanie Steyn

    2014-06-01

    Full Text Available Changes in the South African media and management environment have had distinct influences on especially small to medium-sized mainstream media enterprises (media SMEs which often have to compete with bigger media organisations for the same news stories. Moreover, these media organisations are commonly faced with unique challenges related to human and other resources. This situation adds to the importance of effective and efficient management practices at these media sites. The management practices of first-line news managers in media SMEs are qualitatively and quantitatively evaluated in this paper by considering six managerial competencies found in general management theory. These competencies relate to communication, planning and administration, teamwork; strategic action, global awareness and self-management.

  8. Development of Proof-of-Concept Units for the Advanced Medium-Sized Mobile Power Sources (AMMPS) Program

    Energy Technology Data Exchange (ETDEWEB)

    Andriulli, JB

    2002-04-03

    The purpose of this report is to document the development of the proof-of-concept units within the Advanced Medium-sized Mobile Power Sources (AMMPS) program. The design used a small, lightweight diesel engine, a permanent magnet alternator, power electronics and digital controls as outlined in the philosophy detailed previously. One small proof-of-concept unit was completed and delivered to the military. The unit functioned well but was not optimized at the time of delivery to the military. A tremendous amount of experience was gained during this phase that can be used in the development of any follow-on AMMPS production systems. Lessons learned and recommendations for follow-on specifications are provided. The unit demonstrated that significant benefits are possible with the new design philosophy. Trade-offs will have to be made but many of the advantages appear to be within the technical grasp of the market.

  9. How a health and safety management training program may improve the working environment in small- and medium-sized companies.

    Science.gov (United States)

    Torp, Steffen

    2008-03-01

    The objective of this controlled intervention study was to investigate the effects of a 2-year training program in health and safety (H&S) management for managers at small- and medium-sized companies. A total of 113 managers of motor vehicle repair garages participated in the training and another 113 garage managers served as a comparison group. The effects were measured using questionnaires sent before and after the intervention to the managers and blue-collar workers at the garages. The intervention group managers reported significantly greater improvement of their H&S management system than the managers in the comparison group. The results also indicate that the management training positively affected how the workers regarded their supportive working environment. H&S management training may positively affect measures at both garage and individual levels.

  10. Environmental management in small and medium-sized companies: an analysis from the perspective of the theory of planned behavior.

    Directory of Open Access Journals (Sweden)

    Agustín J Sánchez-Medina

    Full Text Available In the business context, concern for the environment began to develop when pressure from the public administration and environmental awareness groups raised the specific requirements for companies. The Theory of Planned Behavior considers that people's conduct is determined by the intention of carrying out a certain behavior. Thus, the individual's intent is determined by three factors related to the desired outcome of the behavior: the Personal Attitude toward the Results, the Perceived Social Norms, and the Perceived Behavioral Control over the action. Therefore, the objectives of this paper are to clarify the attitudes of the managers of Canarian small and medium-sized companies about taking environmental measures, and try to demonstrate whether there is a relationship between the proposed factors and the intention to take these measures.

  11. Environmental Management in Small and Medium-Sized Companies: An Analysis from the Perspective of the Theory of Planned Behavior

    Science.gov (United States)

    Sánchez-Medina, Agustín J.; Romero-Quintero, Leonardo; Sosa-Cabrera, Silvia

    2014-01-01

    In the business context, concern for the environment began to develop when pressure from the public administration and environmental awareness groups raised the specific requirements for companies. The Theory of Planned Behavior considers that people's conduct is determined by the intention of carrying out a certain behavior. Thus, the individual's intent is determined by three factors related to the desired outcome of the behavior: the Personal Attitude toward the Results, the Perceived Social Norms, and the Perceived Behavioral Control over the action. Therefore, the objectives of this paper are to clarify the attitudes of the managers of Canarian small and medium-sized companies about taking environmental measures, and try to demonstrate whether there is a relationship between the proposed factors and the intention to take these measures. PMID:24533094

  12. Business competitiveness in the small and medium-sized enterprises of the manufacturing sector in Baja California

    Directory of Open Access Journals (Sweden)

    Manuel Alejandro Ibarra Cisneros

    2017-01-01

    Full Text Available The objective of this research is to determine the competitiveness level of the manufacturing small and medium-sized enterprises (SMEs of Baja California and to identify which areas within them affect this competitiveness. The methodology used is descriptive, correlational, and cross-sectional; the systemic competitiveness model is developed at the micro level, and a measurement instrument with 64 questions is used on 195 companies in the state; in addition, traditional multiple linear regressions are performed to test the hypotheses. One of the findings is that the SMEs in the state have a medium-low competitiveness level and do not show any relationship between the size of the companies and their competitiveness; however, the production-operations area prove to be more important for their competitiveness level. Although the measurement instrument that is used has no proportionality at the municipality and subsector level, it does allow us to approach the internal operation of the SMEs.

  13. Influence of information technology management on the organizational performance of the small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    José Melchor Medina

    2011-12-01

    Full Text Available This research analyzes the degree of influence that the use of information management and information technology has on the organizational performance in terms of competitiveness, innovation, and productivity of the small and medium-sized enterprises in the central region of the state of Tamaulipas, Mexico. Data were collected by means of a questionnaire and analyzed by using a Partial Least Squares; the results show a greater support from the information technology and information management variables to innovation (standardized path=0.418 and 0.367, and p<0.05* both. This means that by having an efficient information management process, enterprises are able to get new goods/services, to identify new markets and to face competition.

  14. SOCIAL CAPITAL FOR KNOWLEDGE MANAGEMENT: THE CASE OF SMALL AND MEDIUM-SIZED ENTERPRISES IN THE ASIA-PACIFIC REGION

    Directory of Open Access Journals (Sweden)

    Banjo G. Roxas

    2008-01-01

    Full Text Available This article proposes a conceptual framework that explains that the social capital of a community shapes the innovation performance of small and medium-sized enterprises (SMEs through knowledge management within the firm. The study's significance stems from the unprecedented effort in explaining how community social capital matters in the innovation performance of SMEs, a departure from previous studies that have typically examined market-related or hierarchical social capital in the form of formal networks and directly linked them to a firm's innovation performance without due regard for knowledge management within the firm as an antecedent of organisational innovation performance. The aim is to stimulate further thinking and empirical research on the subject of social capital of a community in the SME and/or entrepreneurial context.

  15. Which benefits and limits derive from ESA membership for European Countries owning ;medium-sized; space agencies?

    Science.gov (United States)

    Petroni, Giorgio; Bigliardi, Barbara; Galati, Francesco; Petroni, Alberto

    2018-01-01

    This study investigates the benefits and limits deriving from membership with ESA of six medium-sized space agencies in terms of strengthening and development (or not) of space technologies, as well as their contribution to the growth of productive activities and to the increase of services for citizens. This research contributes to the more general issue of the usefulness of space activities, not only for scientific or military-political purposes but also for economic and social development. Results show that, on the one hand, the membership with ESA has allowed smaller Countries to access space programs, to develop advanced technologies and to support the growth of their firms in some significant markets, but, on the other hand, the membership has also limited the access to space to few companies, without encouraging the broad dissemination of technological knowledge.

  16. Analysis of the quality of service of small and medium size hotel companies in Bucaramanga and its metropolitan area

    Directory of Open Access Journals (Sweden)

    Carolina Monsalve Castro

    2015-12-01

    Full Text Available In recent years, the hotel industry has been facing an increment of travelers willing to enjoy better conditions in tourist destinations. The demanding changes in tourist preferences, and the increasing range of offers that they find to meet their needs, has made the hotel industry to focus its attention to service. Therefore, in this document, the principles that impact the evaluation of a quality service are analyzed. This research takes a sample of 384 small and medium size hotel companies’ guests. A Likert type questionnaire is applied. Its evaluation is conducted through SPSS software through bivariate analysis. In the results, influential aspects were identified such as: encouraging customer loyalty, special offers, innovation, premises and equipment, human talent training, among others.

  17. Small and medium-sized enterprises’ exporting: Home and host country motivators effect on first and successive export venture decisions

    Directory of Open Access Journals (Sweden)

    Vassilios Stouraitis

    2016-06-01

    Full Text Available The aim of the paper is to investigate the internationalization (particularly exporting of small and medium-sized enterprises (SMEs taking a sample of United Kingdom (UK SMEs for the use in economic policy, academia and management. It focuses on the critical first and less risky step towards internationalization and separates the motivators into home country and host country. The paper investigates 44 specific, high impact, pre-selected exporting motivators from the literature and tests their effect on the firm’s initial export decision and latest (or sequential export decision. Results show that the first exporting choice affects later exporting choices and both are mostly affected by home country-specific, internal, motivators as opposed to host country-specific reactive motivators. In addition regionalization shows an association as European Union membership of the UK showed a relationship to subsequent entry mode choice. The paper’s results are of use to policy-makers and management.

  18. Context-Driven Exploration of Complex Chemical Reaction Networks.

    Science.gov (United States)

    Simm, Gregor N; Reiher, Markus

    2017-12-12

    The construction of a reaction network containing all relevant intermediates and elementary reactions is necessary for the accurate description of chemical processes. In the case of a complex chemical reaction (involving, for instance, many reactants or highly reactive species), the size of such a network may grow rapidly. Here, we present a computational protocol that constructs such reaction networks in a fully automated fashion steered in an intuitive, graph-based fashion through a single graphical user interface. Starting from a set of initial reagents new intermediates are explored through intra- and intermolecular reactions of already explored intermediates or new reactants presented to the network. This is done by assembling reactive complexes based on heuristic rules derived from conceptual electronic-structure theory and exploring the corresponding approximate reaction path. A subsequent path refinement leads to a minimum-energy path which connects the new intermediate to the existing ones to form a connected reaction network. Tree traversal algorithms are then employed to detect reaction channels and catalytic cycles. We apply our protocol to the formose reaction to study different pathways of sugar formation and to rationalize its autocatalytic nature.

  19. Enhancing work motivation for Japanese female nurses in small to medium-sized private hospitals by analyzing job satisfaction.

    Science.gov (United States)

    Kudo, Yasushi; Kido, Shigeri; Shahzad, Machiko Taruzuka; Shida, Kyoko; Satoh, Toshihiko; Aizawa, Yoshiharu

    2010-03-01

    Proper work environments are important for nurses to feel motivated. We examined the associations between work motivation and job satisfaction among Japanese nurses to improve their motivation. In Japan, relatively small and medium-sized private hospitals play a central role in the healthcare industry. In the present study, the subjects were nurses working in 23 small and medium-sized private hospitals that had 65 to 326 beds. We analyzed 1,116 registered and licensed practical female nurses (average age, 38.3 years; standard deviation, 11.3 years). Many nurses with their specialized nursing skills dedicate themselves to patient care. However, many of these nurses may not be interested in contributing to their hospitals. Nurses may have different opinions regarding dedication to patient care and contribution to their hospitals. Therefore, concerning work motivation, we produced these two different items, "Nurses' dedication to patients" and "Nurses' contribution to their hospitals." We also produced our own original new job satisfaction questionnaire. We found 7 facets of job satisfaction: "Work as specialists," "Workplace safety," "Relationships with superiors," "Work-life balance," "Relationships among nurses," "Communications with physicians," and "Salary." Multiple linear regression analyses show that both "Nurses' dedication to patients" and "Nurses' contribution to their hospitals" were significantly associated with "Work as specialists." Nurses feel their jobs of protecting people's lives and health are valuable. They do not feel motivated only by money. They value the intrinsic nature of their jobs. Creating proper work environments is important for nurses to be able to work as specialists.

  20. Determinants of small and medium sized fast growing enterprises in central and eastern Europe: a panel data analysis

    Directory of Open Access Journals (Sweden)

    Miroslav Mateev

    2010-09-01

    Full Text Available The purpose of this paper is to explore the main determinants of growth in small and medium sized enterprises (SMEs in central and eastern Europe. The important role played by SMEs in the economic development of central and eastern European (CEE countries has attracted the recent attention of academics and policymakers but remains relatively unexplored. Empirical research has suggested that firm growth is determined not only by the traditional characteristics of size and age but also by other firm-specific factors such as indebtedness, internal financing, future growth opportunities, process and product innovation, and organisational changes. Although growth in manufacturing and service SMEs in transition economies is well explained by the traditional firm characteristics of size and age, there is no empirical evidence concerning what other specific factors may be associated with SME growth and performance in these countries. Using a panel dataset of 560 fast growing small and medium enterprises from six transition economies we find that firm size when measured by firm total assets can explain to a large extent the growth in SMEs in these countries. When size is proxied by a firm’s number of employees the observed effect is marginal. Firm specific characteristics such as leverage, current liquidity, future growth opportunities, internally generated funds, and factor productivity are found to be important factors in determining a firm’s growth and performance. Age and ownership do not seem to be able to explain firm growth. The results of our empirical study have also some policy implications: we argue that governments in transition economies need to pay an increased attention to small and medium sized enterprises and try to create a business environment that will be beneficial for SME development.

  1. The Alignment System for a Medium-Sized Schwarzschild-Couder Telescope Prototype for the Cherenkov Telescope Array

    Science.gov (United States)

    Ribeiro, Deivid; Humensky, Brian; Nieto, Daniel; V Vassiliev Group in UCLA division of Astronomy and Astrophysics, P Kaaret Group at Iowa University Department of Physics and Astronomy, CTA Consortium

    2016-01-01

    The Cherenkov Telescope Array (CTA) is an international project for a next-generation ground-based gamma-ray observatory. CTA, conceived as an array of tens of imaging atmospheric Cherenkov telescopes, comprising small, medium and large-size telescopes, is aiming to improve on the sensitivity of current-generation experiments by an order of magnitude and provide energy coverage from 20 GeV to more than 300 TeV. The Schwarzschild-Couder design is a candidate 9-m diameter medium-sized telescope featuring a novel aplanatic two-mirror optical design capable of a wide field of view with significantly improved imaging resolution as compared to the traditional Davies-Cotton optical design. Achieving this imaging resolution imposes strict mirror alignment requirements that necessitate a sophisticated alignment system. This system uses a collection of position sensors between panels to determine the relative position of adjacent panels; each panel is mounted on a Stewart platform to allow motion control with six degrees of freedom, facilitating the alignment of the optical surface for the segmented primary and secondary mirrors. Alignments of the primary and secondary mirrors and the camera focal plane with respect to each other are performed utilizing a set of CCD cameras which image LEDs placed on the mirror panels to measure relative translation, and custom-built auto-collimators to measure relative tilt between the primary and secondary mirrors along the optical axis of the telescope. In this contribution we present the status of the development of the SC optical alignment system, soon to be materialized in a full-scale prototype SC medium-size telescope (pSCT) at the Fred Lawrence Whipple Observatory in southern Arizona.

  2. Patterns and Pathways of Evolving Catchment Response in a Medium-Sized Mediterranean Catchment on a Millennium Scale

    Science.gov (United States)

    van Beek, L. P. H.; Bierkens, M. F. P.

    2012-04-01

    The meso-scale landscape dynamics model, CALEROS, has been developed to simulate the interactions between climate, soil production and erosion, vegetation and land use on geomorphological to human time scales in Mediterranean environments. Starting from an initial landscape consisting of a DTM, soil distribution and underlying lithology, the landscape is free to develop in response to the imposed climate variability and seismicity. In addition to changes in soil distribution and bedrock lowering, this includes the establishment of vegetation as conditioned by a selection of plant functional types and, optionally, population and land use dynamics as conditioned by land use scenarios specifying technological and dietary constraints for different periods. As such CALEROS is well-suited to investigate the relative impacts of climate, land cover and human activities on the hydrological catchment response and the associated sediment fluxes due to soil erosion and mass movements. Here we use CALEROS to i) investigate the redistribution of water and sediment across the landscape in a medium-sized Mediterranean catchment (Contrada Maddalena; ~14km2, Calabria, Italy) and ii) to establish patterns of co-evolution in soil properties and vegetation under pristine and anthropogenically impacted conditions on a millennium-scale. Using summary statistics to describe the emergent properties and to verify them against observations, we then delineate areas of uniform morphology and describe the various pathways of development. This information allows us to identify elements of consistent hydrological response and the associated transfer of material across different scales. It also provides essential information on essential feedbacks and the resulting convergence or divergence in landscape development under the impact of climatic or seismic events or human intervention. Although the results are evidently conditioned by the physiographic setting of the study area and by the

  3. VerdEE: a new tool for the adoption of life-cycle assessment in small- and medium-sized enterprises

    Science.gov (United States)

    Masoni, Paolo; Scimia, Emanuela; Sara, Balazs

    2001-02-01

    Data and time requirements and complex methodological problems of a detailed Life Cycle Assessment (LCA) are well-known and discussed. Its application has specific difficulties in Italian Small- and Medium- sized Enterprises (SMEs) where environmental information is generally dispersed, a short-term problem-oriented environmental management approach is common and dedicated human resources are usually missing. As a consequence, a new procedure specifically designed for SMEs, VerdEE (Verifica dell'Eco-Efficienza - Verification of Eco-Efficiency), was developed and implemented on an interactive CD-ROM. It is based on the following criteria: relying on a life cycle approach; aimed at evaluating the environmental profile of a product and at identifying improvement opportunities; sufficiently simple to be applied in a limited time; containing as much quantitative information as possible to make it usable by a non-expert user. The VerdEE procedure includes four main steps: "Goal and Scope definition" semi-quantitative "Inventory" "Check-list" visualisation of results in "Matrix" and "Target-plot" form. The procedure is supported by an interconnected informative part about advantages of the life cycle approach for SMEs, principles of eco-design and environmental concerns.

  4. Influence of product innovations on financial performance of small and medium-sized enterprises in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Jakub Tabas

    2012-01-01

    Full Text Available Objective of this article is to determine possible effect of product innovations on the financial performance of small and medium-sized enterprises in the Czech Republic. The pilot research has been realized on the statistical sample of 100 companies which were categorized into three basic groups; service companies, trade companies, and production companies. As the measure of innovation effect, the authors applied the deviation of production power, i.e. the ration of EBIT to assets, of a business entity from the industry average while the industry average of production power was selected especially in order to reduce the influence of the economy cycles. In the three categories of companies, different effects of product innovations have been observed. In the service companies and trade companies, the positive effect is limited because of potential simplicity of imitation by competitors. More positive effect of product innovations has been observed in production companies which can protect the products or production processes better then service companies or trade companies where the product innovations are mostly connected with extension of extension of services portfolio offered. For the conclusion, the authors provide suppositions and designs for their future research in this problem of innovations’ effectiveness measurement.

  5. Uncertainties of Completeness Measures in Openstreetmap - a Case Study for Buildings in a Medium-Sized German City

    Science.gov (United States)

    Törnros, T.; Dorn, H.; Hahmann, S.; Zipf, A.

    2015-08-01

    The completeness of buildings in OpenStreetMap (OSM) is estimated for a medium-sized German city and its surroundings by comparing the OSM data with data from an official building cadastre. As completeness measures we apply two unit-based methods that are frequently applied in similar studies. It is found that the estimation of OSM building completeness strongly differ between the methods. A count ratio (number of OSM buildings / number of reference buildings) tends to underestimate the actual building completeness and an area ratio (total OSM building area / total reference building area) instead tends to overestimate the completeness within the study area. It is argued that a simple pre-processing of the building footprint polygons leads to a more accurate completeness estimation when applying the count ratio. It is also suggested to more carefully examine the areas that have been mapped in OSM but not in the reference data set (false positives). In the present study region, these values are mainly due to simplified OSM polygons and they contribute to an overestimation of the OSM building completeness when applying the area ratio.

  6. Software-as-a-Service and Cloud Computing, a solution for small and medium-sized companies

    Directory of Open Access Journals (Sweden)

    Bajenaru, A.

    2010-12-01

    Full Text Available Small and medium-sized companies are an important part of today’s world economy, for their ability to offer new jobs but also for their capacity of innovation. At the same time, they are in a constant struggle with larger companies that take advantage of their negotiating power to impose their way of doing business to the SMEs. In an ICT enabled world, most large companies being intense ICT users, the lag of ICT adoption in SMEs may create a strong barrier between SMEs and large companies, promoting an over growing digital divide, the SMEs being in danger of being left out in some economic sectors. This paper aims at finding a possible solution in the Software-as-a-Service and Cloud Computing model, a rather new solution, yet more and more sought off by SMEs but also larger companies, especially considering the global financial and economic crisis, as well as evaluating the European Union’s main views and policies regarding the SAAS – Cloud model.

  7. The Franchising in the Context of Development of Small and Medium-Sized Business: Organizational-Economic and Accounting Aspects

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    Makhota Alla V.

    2017-05-01

    Full Text Available In order to determine the organizational-economic and accounting aspects of franchising in the context of volatility of the macro-economic situation and the scarcity of entrepreneurs’ own funds, the current status of the franchising market in Ukraine, its economic essence and its role have been determined; the kinds of franchising that are known in world business practices have been provided; the types of distribution contracts that are close to the meaning of franchising have been defined; the legislative basis for franchising in Ukraine has been presented; the binding terms of a commercial concession contract as a legislated analogy of franchising in Ukraine have been determined; the features of reflection of the legality of franchising in accounting of both franchiser and franchisee have been provided. The objective advantages of franchising for both the large enterprises and the start-up entrepreneurs have been determined. On the basis of the legal nature of franchising relations in the accounting accounting, its reflection is close in the meaning to intangible assets. Implementation of franchising potential as a strategic tool for the development of small and medium-sized businesses requires the improvement of its legislative framework in the part of enhancing the responsibility of the parties.

  8. The possible ways to IFRS (International Financial Reporting Standards for SME (Small and Medium sized Entities development

    Directory of Open Access Journals (Sweden)

    Hana Bohušová

    2007-01-01

    Full Text Available The most business entities in Europe are small or medium-sized enterprises (SME, which have a legal obligation to prepare financial statements in accordance with a set of accounting principles accepted in their country. Those statements are available to creditors, suppliers, and national governments but they could be badly understandable to creditors, suppliers and subjects in other countries. This is a great obstacle of their activities in the EU internal market. The existence of 27 different national accounting systems in the EU can be held for the most important obstacle.There are many ways how to develop compatible accounting standards for SMEs but the most significant activity in this field is the research project of IASB (International Accounting Standards Board. IASB has developed IFRS (International Financial Reporting Standards. Even though IFRS are suitable for all enterprises, their application in case of SMEs would be very expensive and could significantly increase compliance costs of taxation. This development has not been finished yet and there are still some problems which need to be solved before the introduction of accounting standards to the public. The research has shown that IFRS for SMEs should be used mainly by the entities which do not have public accountability – i.e. that its equities are not publicly traded and do not hold assets in a fiduciary capacity for a broad group of outsiders. This paper discusses those IFRS modifications, which should be done in case of SMEs.

  9. The impact of corporate social responsibility factors on the competitiveness of small and medium-sized enterprises

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    Peter Turyakira

    2014-03-01

    Full Text Available Corporate social responsibility (CSR has become increasingly important to the competitiveness of small and medium-sized enterprises (SMEs. A positive relationship between the CSR activities of SMEs and their enhanced competitiveness exists, at least if a long-term perspective is adopted (European Competitiveness Report, 2008:106; Mandl & Dorr, 2007:2. Despite the widespread practical and academic interest in CSR and its impact on the competitiveness of SMEs, few theoretical and empirical contributions could be found. The primary objective of this study was to identify and empirically test the CSR factors influencing the competitiveness of SMEs in Uganda. The outcomes of this study will assist SMEs to effectively and responsibly manage their activities to increase their competitiveness. A structured, self-administered questionnaire was distributed to 750 potential SME respondents. The respondents were identified by means of a purposive sampling technique, and the data were collected from 383 usable questionnaires. An exploratory factor analysis was carried out, and Cronbach’s alpha coefficients calculated to determine the discriminant validity and reliability of the measuring instrument. Correlations were assessed using structural equation modeling. The empirical results of this study indicate that workforce-oriented CSR activities, society-oriented CSR activities, market-oriented CSR activities and regulated CSR activities significantly influence the competitiveness of SMEs.

  10. [The certification of advanced therapy medicinal products. A quality label for product development in small and medium-sized enterprises].

    Science.gov (United States)

    Berger, A; Schüle, S; Flory, E

    2011-07-01

    Advanced therapy medicinal products (ATMPs) are gene therapy, cell therapy, and tissue engineered products. To gain access to the market within the European Union, ATMPs must be authorized by the European Commission (EC). Especially for small and medium-sized enterprises (SMEs), the European centralized procedure of marketing authorization that is conducted by the European Medicines Agency (EMA) constitutes a major challenge, because SMEs often have little experience with regulatory procedures and many have limited financial possibilities. To tackle these challenges, a certification procedure exclusively for SMEs and their ATMP development was introduced by the EC. Independently from a marketing authorization application, development and/or production processes can be certified. An issued certificate demonstrates that the respective process meets the current regulatory and scientific requirements of the EMA, representing a valuable milestone for putative investors and licensees. This article highlights the background, the detailed procedure, the minimum requirements, as well as the costs of certification, while giving further noteworthy guidance for interested parties.

  11. Risk determinants of small and medium-sized manufacturing enterprises (SMEs) - an exploratory study in New Zealand

    Science.gov (United States)

    Islam, Ariful; Tedford, Des

    2012-08-01

    The smooth running of small and medium-sized manufacturing enterprises (SMEs) presents a significant challenge irrespective of the technological and human resources they may have at their disposal. SMEs continuously encounter daily internal and external undesirable events and unwanted setbacks to their operations that detract from their business performance. These are referred to as `disturbances' in our research study. Among the disturbances, some are likely to create risks to the enterprises in terms of loss of production, manufacturing capability, human resource, market share, and, of course, economic losses. These are finally referred to as `risk determinant' on the basis of their correlation with some risk indicators, which are linked to operational, occupational, and economic risks. To deal with these risk determinants effectively, SMEs need a systematic method of approach to identify and treat their potential effects along with an appropriate set of tools. However, initially, a strategic approach is required to identify typical risk determinants and their linkage with potential business risks. In this connection, we conducted this study to explore the answer to the research question: what are the typical risk determinants encountered by SMEs? We carried out an empirical investigation with a multi-method research approach (a combination of a questionnaire-based mail survey involving 212 SMEs and five in-depth case studies) in New Zealand. This paper presents a set of typical internal and external risk determinants, which need special attention to be dealt with to minimize operational risks of an SME.

  12. Conducting Creativity Brainstorming Sessions in Small and Medium-Sized Enterprises Using Computer-Mediated Communication Tools

    Science.gov (United States)

    Murthy, Uday S.

    A variety of Web-based low cost computer-mediated communication (CMC) tools are now available for use by small and medium-sized enterprises (SME). These tools invariably incorporate chat systems that facilitate simultaneous input in synchronous electronic meeting environments, allowing what is referred to as “electronic brainstorming.” Although prior research in information systems (IS) has established that electronic brainstorming can be superior to face-to-face brainstorming, there is a lack of detailed guidance regarding how CMC tools should be optimally configured to foster creativity in SMEs. This paper discusses factors to be considered in using CMC tools for creativity brainstorming and proposes recommendations for optimally configuring CMC tools to enhance creativity in SMEs. The recommendations are based on lessons learned from several recent experimental studies on the use of CMC tools for rich brainstorming tasks that require participants to invoke domain-specific knowledge. Based on a consideration of the advantages and disadvantages of the various configuration options, the recommendations provided can form the basis for selecting a CMC tool for creativity brainstorming or for creating an in-house CMC tool for the purpose.

  13. Using a base of simplified financial plan for determination innovations’ economic effect in small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Jakub Tabas

    2013-01-01

    Full Text Available Currently, innovations seem to be a crucial process in companies in order to at least maintain or even improve their competitiveness. Strengthening global competition puts the stress on continual improvements in every sphere of business entity’s activities. This way, innovations are the almost only tool to maintain customers, subsequently to keep the place on a market or the market share, and then to sustain the financial performance of a company. It means that effect of innovations is closely connected with the financial performance of a business entity that can be measured with various methods or approaches while the financial analysis ratios are supposed to be basic ones. In order to interpret the results of these financial ratios, different bases are used when the base of financial plan is one of them. The objective of this article is to determine the economic effect of innovations on financial performance of small and medium-sized enterprises in the Czech Republic on the base of simplified financial plan. Obviously, starting-point of the financial plan preparation is the plan of sales. Sales represent one of the company’s value generators, and sales projection is constituted as basis of authors’ approach to determination of effect of innovations on financial performance of business entities while basic categorization of companies according to the business branch (CZ NACE, sphere of innovation and innovation’s degree is applied.

  14. Mass Housing Neighbourhoods in Medium-Sized Andalusian Cities. Between Historic City Centres and New Peripheral Developments

    Science.gov (United States)

    Navas-Carrillo, Daniel; Pérez-Cano, María Teresa; Rosa-Jiménez, Carlos

    2017-10-01

    This paper aims to analyse the evolution experienced by the neighbourhoods that comprise the so-called first periphery. Most of them have been thoroughly studied, has led to recognize theirs values and to be included in the catalogues of heritage protection of their respective cities. However, this research shows that is pending an in-depth analysis in cities of intermediate scale. Its significance lies not only in the fact that they are the most significant operations of architecture of the modern movement in their respective cities, but are especially noteworthy the values derived from its strategic location within the urban structure of these intermediate scale cities. Being near to city centre, they have been constituted as transition pieces between historic sites, new peripheral developments, and even, their nearest territory. As method, this research proposes a comparative analysis of traceability among different study cases, from medium-sized cities of the Andalusian Coast (Spain). In this context, it means recording the evolution that these promotions have been experienced since their first designs until their current situation. It attempts to find the characteristics that have resulted in the urban configuration of this periphery and to recognize the sum of all the cultural, economic, social and technological aspects that conditions the ways of life that today are detected in them. Definitely, the knowledge generated by this research allows extracting architectural and urban values of these examples, which justify its necessary dissemination as part of our legacy.

  15. MCDA-C Methodology Based Performance Evaluation of Small and Medium-Sized Businesses at the City of Lages

    Directory of Open Access Journals (Sweden)

    Marcelo Nascimento

    2013-12-01

    Full Text Available When employed in a focused manner, corporate performance evaluation has proven to be instrumental for entrepreneurs as an important tool that contributes with performance improvements at their organizations. The descriptive study herein, prepared as of a questionnaire comprising 46 queries, poses to analyse the performance of micro and small companies (MSEs by employing the multicriteria methodology for constructive decision aiding (MCDA-C. As of respondent replies, MCDA-C descriptors were formed, shaping six prime groups so as to identify relevant factors that drive or hinder MSE success. The questionnaire was applied to managers in charge administering 25 small and medium-sized companies of Lages, a city within the Brazilian state of Santa Catarina. Study findings provide evidence as to the fact that (i 24% of surveyed companies, tend to go bankrupt; (ii managerial functions at the MSEs are the prime source of influence on negative outcomes; (iii from a financial control standpoint, surveyed companies fall far shorter than the minimum level deemed necessary to qualify as satisfactory; (iv those that present the best results, operate both within the domestic and international markets; (v the study placed under the spotlight the group “Evolution Stage”, evidencing the trend of ever increasing MSE expansion. This study revealed that corporate failure contributing factors are intensely interconnected and largely depend on the entrepreneur´s own performance, the prime contribution of findings residing in demonstrating that MCDA-C can be employed to analyse the performance of micro and small businesses.

  16. Designing and Validating a Model for Measuring Sustainability of Overall Innovation Capability of Small and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Mohd Nizam Ab Rahman

    2015-01-01

    Full Text Available The business environment is currently characterized by intensified competition at both the national and firm levels. Many studies have shown that innovation positively affect firms in enhancing their competitiveness. Innovation is a dynamic process that requires a continuous, evolving, and mastered management. Evaluating the sustainability of overall innovation capability of a business is a major means of determining how well this firm effectively and efficiently manages its innovation process. A psychometrically valid scale of evaluating the sustainability of overall innovation capability of a firm is still insufficient in the current innovation literature. Thus, this study developed a reliable and valid scale of measuring the sustainability of overall innovation capability construct. The unidimensionality, reliability, and several validity components of the developed scale were tested using the data collected from 175 small and medium-sized enterprises in Iran. A series of systematic statistical analyses were performed. Results of the reliability measures, exploratory and confirmatory factor analyses, and several components of validity tests strongly supported an eight-dimensional (8D scale of measuring the sustainability of overall innovation capability construct. The dimensions of the scale were strategic management, supportive culture and structure, resource allocation, communication and networking, knowledge and technology management, idea management, project development, and commercialization capabilities.

  17. MuSAE: A European Project for the Diffusion of Energy and Environmental Planning in Small-Medium Sized Municipalities

    Directory of Open Access Journals (Sweden)

    Giorgio Baldinelli

    2015-12-01

    Full Text Available The basic idea of the EU LIFE+ 2011 project MuSAE (“Municipalities Subsidiarity for Actions on Energy”, code LIFE11 ENV/IT/000016 consists of transferring the skills and experience related to energy planning, acquired by the leading beneficiary, the Municipality of Perugia, to three small- or medium-sized Umbrian Municipalities (Marsciano, Umbertide and Lisciano Niccone. This transfer is aimed, among other objectives, at the drafting of the Municipal Energy and Environmental Plan (MEEP and the opening of an energy information office in each partner Municipality, in cooperation with CIRIAF and Umbria Region. The present paper provides a summary of MuSAE activities, analyzing the procedures and modalities of implementation of the various phases of the MEEPs, on the basis of the experience gained over the years through the collaboration with the Municipality of Perugia and adapted to smaller territories such as those represented by the other partner Municipalities. A summary of the dissemination activities and pilot projects is also presented, testifying the first concrete results of the planning activity developed by each administration within the project.

  18. Estimation of the Treatment Effects of Ownership on the Indirect Financing of Small- and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Xiuzhen Wang

    2014-01-01

    Full Text Available Small- and medium-sized enterprises (SMEs are the important driving forces for the growth of China’s economy. However, financing difficulty has always been the important problem besetting the development of SMEs for a long time. In particular, in recent years, US subprime crisis in 2008 caused a heavy blow to the development of some externally oriented SMEs. Thus, how to effectively overcome financing predicament for the SMEs is crucial for Chinese government. In this paper, based on microdata from China Industrial Enterprise Database, propensity score matching (PSM method is adopted to conduct empirical analysis about the treatment effects of indirect financing level of SMEs under different systems. Empirical results reveal that state-owned enterprises enjoy indirect financing advantages compared with other enterprises and there is certain ownership discrimination against foreign-funded enterprises and private enterprises. In particular, the indirect financing rate of state-owned enterprises is 1.4% higher than that of other enterprises, and the indirect financing rate of foreign-funded enterprises is 6% lower than that of other enterprises; private enterprises are advantageous in indirect financing compared with other enterprises; however, indirect financing rate of private enterprises is 1.8% lower than that of state-owned enterprises, which also reveals ownership discrimination to certain extent.

  19. Boys who pee the farthest have a large hollow head, a thin skin, and medium-size manhood

    Science.gov (United States)

    Attinger, Daniel; Lee, Vincent

    2016-11-01

    Following a recent trend of scientific studies on artwork, we study here the thermodynamics of a jetting thermometer made of ceramic, related to the Chinese tea culture. The thermometer represents a boy who "urinates" shortly after hot water is poured onto his head. Long jetting distance indicates if the water temperature is hot enough to brew tea. Here, a thermofluid model describes the jetting phenomenon of that pee-pee boy. The study demonstrates how thermal expansion of an interior air pocket causes jetting. The validity of assumptions underlying the Hagen-Poiseuille flow is discussed for urethra of finite length. A thermodynamic potential is shown to define maximum jetting velocity. Seven optimization criteria to maximize jetting distance are provided, including two dimensionless numbers. The dimensionless numbers are obtained by comparing the time scales of the internal pressure buildup due to heating, with that of pressure relief due to jetting. Optimization results show that longer jets are produced by large individuals, with low body mass index, with a boyhood of medium size inclined at an angle π/4. Analogies are drawn with pissing contests among humans and lobsters. The study ends by noting similitudes of working principle between that politically incorrect thermometer and Galileo Galilei's thermoscope.

  20. Factors Influencing Sustainable Entrepreneurship in Small and Medium-Sized Enterprises in Iran: A Case Study of Food Industry

    Directory of Open Access Journals (Sweden)

    Gholamhossein Hosseininia

    2016-10-01

    Full Text Available This study sought to establish the social and environmental factors that influence sustainable entrepreneurship (SE in Small- and medium-sized enterprises (SMEs. It also attempted to identify whether the demographic background of the entrepreneur influences the SE in SMEs of the Iranian food industry. A mixed method approach, employing the use of questionnaires and interviews from a sample size of approximately 130 participants and 12 owner-managers of SMEs in food industry, was used to collect data. Data were analyzed using descriptive statistics and several inferential analyses. Findings showed that certain characteristics of the entrepreneur, including work experience and education, have a significant impact on SE. Furthermore, out of the eight identified factors, according to the participants’ perception, the most important factors towards sustainable performance of SMEs in food industry are social factors, including customer orientation, as well as human resources and environmental factors, including recycling and the future of Earth. This research paper concludes that considering the social and environmental aspects of sustainability and employing experienced staff would majorly contribute to the pursuit of SE in SMEs of food industry.

  1. An Influence of Strategic Awareness on Management Control: Evidence from Polish Micro, Small and Medium-sized Enterprises

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    Joanna Dyczkowska

    2015-03-01

    Full Text Available Purpose: The paper investigates whether employees’ strategic awareness influences the shape of management control systems (MCSs in Polish micro, small and medium-sized enterprises (mSMEs. Methodology: The study is based on data obtained from 223 companies between November 2010 and January 2012. The quantitative analysis used a set of variables which depicted MCSs: ‘goalsetting process’, ‘control framework’ and ‘organisation of control’. Strategic awareness was considered an independent variable. Findings: The results showed positive correlations between strategic awareness and considered variables. Regression models developed by the authors proved statistically valid. The study evidences, that increasing employees’ strategic awareness stimulates their participation in goal-setting, contributes to the development of more comprehensive MCSs, or may even imply formalisation of management control. Research limitations: The study does not include an analysis of the extent to which employees find MCSs useful in their work. This will be considered in future research. Another possible extension of the project is to identify factors which enable the capturing of the dynamic character of MCSs and their changes over time. Practical implications: The knowledge of MCSs does not explain whether or not the strategic orientation of a company stimulates a need for MCS. Such knowledge may be important to managers who have to face Polish employees’ general aversion to control. Originality: The study contributes to the limited body of knowledge in a scope of relations between employees’ strategic awareness and control mechanisms in Polish mSMEs.

  2. Impact of local urban design and traffic restrictions on air quality in a medium-sized town.

    Science.gov (United States)

    Acero, J A; Simon, A; Padro, A; Santa Coloma, O

    2012-01-01

    Traffic is the major air pollution source in most urban areas. Nowadays, most of the strategies carried out to improve urban air quality are focused on reducing traffic emissions. Nevertheless, acting locally on urban design can also reduce levels of air pollutants. In this paper, both strategies are studied in several scenarios for a medium-sized town of the Basque Country (Spain). Two main actions are analysed in order to reduce traffic emissions: (1) minor extension ofa pre-existing low emission zone (LEZ); (2) substitution of 10% of passenger cars that are older than 5 years by hybrid and electric vehicles. Regarding local urban design, three alternatives for the development of one side of a street canyon are considered: (1) a park with trees; (2) an open space without obstacles; (3) a building. Two different urban traffic dispersion models are used to calculate the air quality scenarios: PROKAS (Gaussian&box) to analyse the reduction of traffic emissions in the whole urban area and WinMISKAM (CFD) to evaluate specific urban designs. The results show the effectiveness of the analysed actions. On one hand, the definition of a small LEZ, as well as the introduction in 2015 of vehicles with new technology (hybrid and electric), results in minor impacts on PM10 and NO2 ambient concentrations. On the other hand, local urban design can cause significant variation in spatial distribution ofpollutant concentrations emitted inside street canyons. Consequently, urban planners should consider all these aspects when dealing with urban air pollution control.

  3. Analyzing the efficiency of small and medium-sized enterprises of a national technology innovation research and development program.

    Science.gov (United States)

    Park, Sungmin

    2014-01-01

    This study analyzes the efficiency of small and medium-sized enterprises (SMEs) of a national technology innovation research and development (R&D) program. In particular, an empirical analysis is presented that aims to answer the following question: "Is there a difference in the efficiency between R&D collaboration types and between government R&D subsidy sizes?" Methodologically, the efficiency of a government-sponsored R&D project (i.e., GSP) is measured by Data Envelopment Analysis (DEA), and a nonparametric analysis of variance method, the Kruskal-Wallis (KW) test is adopted to see if the efficiency differences between R&D collaboration types and between government R&D subsidy sizes are statistically significant. This study's major findings are as follows. First, contrary to our hypothesis, when we controlled the influence of government R&D subsidy size, there was no statistically significant difference in the efficiency between R&D collaboration types. However, the R&D collaboration type, "SME-University-Laboratory" Joint-Venture was superior to the others, achieving the largest median and the smallest interquartile range of DEA efficiency scores. Second, the differences in the efficiency were statistically significant between government R&D subsidy sizes, and the phenomenon of diseconomies of scale was identified on the whole. As the government R&D subsidy size increases, the central measures of DEA efficiency scores were reduced, but the dispersion measures rather tended to get larger.

  4. Presenting a Framework to Analyze Local Climate Policy and Action in Small and Medium-Sized Cities

    Directory of Open Access Journals (Sweden)

    Thomas Hoppe

    2016-08-01

    Full Text Available Academic attention to local climate policy usually focuses on large-sized cities. Given the climate challenges ahead this seems unjustified. Small and medium-sized cities (SMCs deserve scholarly attention as well. The main question is: What factors influence climate change policy and local climate actions in SMCs? In this article we present an analytical framework to analyze climate change policy and local climate actions of SMCs. The framework addresses different aspects: policy-input, -throughput, -output, -outcome, characteristics of the local environment, local action arenas, influence by higher government levels, and interaction with climate change issue networks. The framework is used to analyze and compare four case studies of SMCs in the Dutch region of Twente (two urban and two rural municipalities, and addresses both adaptation and mitigation. Results show that both ‘localist’, ‘multi-level’ and issue network membership factors influence local climate policy action. Governance modes discerned concern mostly ‘governing by authority’ and ‘self-governing’. When reflecting on the role of SMCs in climate action the study revealed the importance of local capacity building schemes issued by provincial government, inter-municipal network collaboration, and the potential for local governments to mobilize and organize citizen action.

  5. CONSIDERATIONS REGARDING THE USE OF MODERN MANAGEMENT METHODS IN PLANNING THE MARKETING ACTIVITY WITHIN THE SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Olteanu Valerica

    2012-07-01

    Full Text Available This paper aims to highlight, from a marketing perspective, the manner and conditions in which small and medium-sized enterprises can use modern management methods in planning the marketing activity. Using modern methods of management are particularly important for managers of these organizations and especially for marketers. Thus, the following methods play a significant role within the marketing activitiesn#8217; development for marketing specialists, namely: management by objectives, management by budgets, management by projects, and management by product. The high degree of understanding and using the above methods is, in the current economic environment, one of the determinants of the market success of small and medium-sized enterprises. In the current context, the adoption of the management by objectives is not a facultative option for the small and medium-sized enterprises, but rather a binding one in the context of adopting and practicing an efficient marketing with significant results on the development of marketing programs comprised within them. Similarly to the management by objectives, the use of the management by budgets within the small and medium-sized enterprises has a series of features required by their smaller size, features that should be considered by marketers. Regarding the use of management by projects, this method has to constitute the foundation for the elaboration of marketing programs developed within the small and medium-sized enterprises, thereby allowing shaping an action that can be accompanied by success in achieving the goals comprised within the marketing programs. Finally, the role of the management by product is extremely important in the marketing activity within the small and medium-sized enterprises, especially in the operationalization of concepts such as strategic marketing and tactical marketing. This paper thus outlines from a marketing point of view the main issues aiming at understanding and using

  6. [The distribution of cardiovascular risk factors in employees from small- and medium-sized enterprises in Germany].

    Science.gov (United States)

    Kaifie, Andrea; Kraus, Thomas

    2018-02-01

    The German Prevention Act, the main parts of which came into force on 25 July 2015, encourages health promotion and prevention programs for people in their living environment. Through this act, preventive measures could reach employees at work that hardly seek medical services. This is of importance since employees with a low occupational position often show risk factors that increase morbidity and mortality. In this study, clinical data from n = 2280 employees from small and medium sized enterprises (SME) were analyzed for economic sector, sex, socioeconomic position (SEP), economic sector cardiovascular risk factors, musculoskeletal and psychological diseases. The socioeconomic position was categorized using the European Socioeconomic Classification into an intermediate/high and a low SEP category. Male employees showed a significantly higher occurrence of risk factors, such as smoking, diabetes or hypertension in comparison to female employees. In the manufacturing industry, male employees with a low SEP showed a higher prevalence of diabetes (2.3 vs. 5.9%), smoking (27.4 vs. 46.5%), and physical inactivity (sports: 55.0 vs. 37.1%) in comparison to employees with an intermediate/high SEP. Male employees with a low SEP from health and social services reported psychiatric disorders more frequently in comparison to those with an intermediate/high SEP (0.7 vs. 5.9%). Male employees with a low SEP should be given special consideration in the implementation of preventive measures at work within the framework of the Prevention Act.

  7. Efficacy of informed versus uninformed physiotherapy on postoperative retear rates of medium-sized and large rotator cuff tears.

    Science.gov (United States)

    Chou, Chin-Tsai; Hu, Weichih; Wen, Che-Sheng; Wang, Su-Fan; Lieu, Fu-Kong; Teng, Jyh-Tong

    2015-09-01

    It is important to perform the first 12 weeks of rehabilitation without risk of tearing a cuff tendon from its repair site. Our hypothesis was that performing early postoperative rehabilitation with a limitable pendulum exercise device can produce lower retear rate outcomes when it is combined with safe, informed physiotherapy compared with a standardized protocol of rehabilitation performed at home. By using an asymmetric arm support brace and an advanced accelerometer, we attempted to determine the benefits of small pendulum exercises (proposed by Long et al). This study enrolled 24 patients to use a monitoring device in standardized small pendulum exercises. Clinical outcomes and magnetic resonance images were evaluated preoperatively and 12 weeks after surgery. While a patient performed pendulum exercises, a therapist used computer imagery to observe whether vertical acceleration was over a given threshold (identified as physiologic tremors), as a warning of and precaution associated with the increased risk of repair failure. Similar self-reported functional outcomes were reported in 2 areas. The rate of recurrent tears was significantly higher for both the medium-sized and large areas in the uninformed home rehabilitation group compared with the informed group. The results of monitoring of pendulum exercises to develop informed physical therapeutic methodology were consistent with those of previously published literature. In this study, use of a monitoring device during early rehabilitation was associated with lower retear rates after rotator cuff repair. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  8. MDCT abnormalities of small- and medium-sized bronchus in active tuberculosis: a new angle on an old disease

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jin Kyoung; Ahn, Myeong Im; Jung, Jung Im; Han, Dae Hee (Dept. of Radiology, Seoul St Mary' s Hospital, The Catholic Univ. of Korea, Seoul (Korea, Republic of)), email: lepolder@gmail.com; Kim, Young Kyoon (Dept. of Internal Medicine, Seoul St Mary' s Hospital, The Catholic Univ. of Korea, Seoul (Korea, Republic of)); Oh, Eun-Jee; Park, Yeon-Joon (Dept. of Laboratory Medicine, Seoul St Mary' s Hospital, The Catholic Univ. of Korea, Seoul (Korea, Republic of))

    2011-02-15

    Background: The incidence and findings of tuberculous invasion of the peripheral bronchus have not been fully investigated with MDCT. Purpose: To evaluate the prevalence and findings of MDCT abnormalities of small- and medium-sized bronchus (SMB) in active pulmonary tuberculosis (TB). Material and Methods: Using multiplanar reformation, 35 consecutive MDCT scans (follow-up exams available in 14 patients with a mean interval of 8.1 months) were assessed for following abnormalities of SMB: bronchial impaction (BI), wall thickening, dilatation, peribronchial cuff of soft tissue, and bronchocavitary fistula. It was also assessed whether tree-in-buds (TIB) have a tendency to distribute in the territories of diseased SMB, and whether SMB abnormalities are present in patients with relatively mild disease. Results: SMB abnormalities were observed in 23 (65.7%) patients with active TB. The most frequent finding was wall thickening (n=18, 51.4%), followed by BI (n=13, 37.1%; zigzag-shaped in four), dilatation (n =11, 31.4%), amputated appearance of air column (n=11, 31.4%), peribronchial cuff of soft tissue (n=10, 28.6%), and bronchocavitary fistula (n=8, 22.9%). TIB (n=29; absent in two patients with SMB) was mainly within (n=14) or close to (n=4) the territory of diseased SMB. Follow-up CT frequently showed improvement of wall thickening (11/12) and persistence of bronchial dilatation (11/13). SMB abnormality was present in all of six patients with mild disease. Conclusion: MDCT shows that tuberculous invasion of the peripheral bronchus may be more frequent than previously thought, of which findings include wall thickening, BI, dilatation, amputated appearance of air column, peribronchial cuff of soft tissue and bronchocavitary fistula

  9. The Potential of Business Environment Institutions and the Support for the Development of Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Renata Lisowska

    2016-09-01

    Full Text Available Objective: The paper aims to assess the use of the potential of business environment institutions to support SMEs in the light of the author's own research. Research Design & Methods: The author's study was carried out in 2012-2014 in two stages: quantitative research (a survey on the sample of 590 SMEs conducted with the use of the PAPI and CAWI methods based on a survey questionnaire and qualitative research conducted among 10 representatives of business environment institutions with the use of in-depth interviews (IDI based on a questionnaire with a standard list of information sought. Findings: The study results suggest that the role of business environment institutions in the development of small and medium-sized enterprises in the present conditions is small. This is a result of, on the one hand, little interest of SMEs in the support offered by these institutions, and, on the other hand, the fact that frequently the services offered do not meet the needs of enterprises. Implications & Recommendations: To improve the situation, on the part of business environment institutions, it is necessary to update information on the scope of cooperation, undertake extensive promotional activities, adjust the offer to the needs of enterprises and expand cooperation, especially by providing financial support for enterprises. Contribution & Value Added: The study can be used for in-depth analyses of support for the SMEs provided by business environment institutions. It can be also useful for decision-makers responsible for creating development policies.

  10. Challenges of small and medium sized companies at early stage of development: Insights from Bosnia and Herzegovina

    Directory of Open Access Journals (Sweden)

    Saša Petković

    2016-12-01

    Full Text Available The purpose of this paper is to discover and understand factors that lead to small and medium-sized enterprises (SMEs shutdown in transitional economies, such as the economy of Bosnia and Herzegovina (B&H. The paper provides some findings about main influencing factors that lead to SMEs shut down in the first years of operation from entrepreneurs’ and managers’ perspective and suggests certain measures that should be taken to secure their survival, development and growth. For the purpose of this paper, empirical research was conducted, using stratified sampling of 110 SMEs from Republic of Srpska (49% of B&H territory. The section on methodology explains the entry criteria for the study population and methods of data analysis. Respondents from the research sample identified the following factors as the main obstacles to successful development of their businesses: difficulties in the collection of receivables from debtors, complicated legal procedures that regulate the work and business operations of enterprises, high rates of taxes and contributions on wages, the negative impact of the global economic crisis and expensive and complicated procedures for obtaining loans from commercial banks. Respondents didn’t evaluate their personal traits, level of formal and informal knowledge from business management field or lack of entrepreneurial spirit and readiness for being proactive, innovative or risk acceptance as potential causes of business failure. With its limitation, the paper contains novel information and insights about SMEs business obstacles and challenges in economy of Bosnia and Herzegovina as a solid base for more comprehensive future research.

  11. Infrastructure deficiency and the performance of small- and medium-sized enterprises in Nigeria’s Liberalised Economy

    Directory of Open Access Journals (Sweden)

    Lawrence O. Obokoh

    2016-03-01

    Full Text Available Orientation: The paper investigates the situation facing SME’s in Nigeria, who have to function in an environment with depleted infrastructure.Research purpose: To examine the effects of infrastructure deficiency on the performance of manufacturing small and medium sized enterprises in Nigeria.Motivation for the study: Low budgetary allocation by the Nigerian government toward investment and rehabilitation of infrastructure in favor of attempts to conform to the tenets of trade liberalisation, has created a situation where basic infrastructure provision is a huge challenge in the creation of SME’s.Research design, approach and method: A longitudinal approach was followed, where a survey was conducted amongst 500 SME’s in Nigeria. To complement this, semi-structured interviews were conducted in 2007 and 2011 respectively. Main findings: The deficiency in infrastructure negatively impacts the profitability and performance of SMEs, due to the high cost incurred by SMEs in the self-provision of infrastructure and distribution of finished goods. Furthermore, despite the successful privatisation of electricity production in November 2013, there is still no significant improvement in the power supply in Nigeria. However, the government has embarked on road rehabilitation to ease the transportation of goods and services.Practical/managerial implications: The study uncovers the practical realities of the challenges faced by SME’s operating in an environment with insufficient infrastructure, which is typical of much of the developing world.Contribution/value add: The study highlights the necessity of sound infrastructure provision as a key factor to the development of SME’s.

  12. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Amancio, C.T. [Departamento de Medicina, Universidade de Taubaté, Taubaté, SP (Brazil); Nascimento, L.F.C. [Departamento de Medicina, Universidade de Taubaté, Taubaté, SP (Brazil); Programa de Pós-Graduação em Ciências Ambientais, Universidade de Taubaté, Taubaté, SP (Brazil)

    2012-08-17

    There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of pollutants, particulate matter, sulfur dioxide (SO{sub 2}), ozone, temperature, and humidity were obtained from the São Paulo State Environmental Agency. Moving average models for 2 to 7 days were calculated by Poisson regression using the R software. Exposure to SO{sub 2} was analyzed using a unipollutant, bipollutant or multipollutant model adjusted for mean temperature and humidity. The relative risks with 95%CI were obtained and the percent decrease in risk was calculated. There were 1928 deaths with a daily mean (± SD) of 1.05 ± 1.03 (range: 0-6). Exposure to SO{sub 2} was significantly associated with mortality due to circulatory disease: RR = 1.04 (95%CI = 1.01 to 1.06) in the 7-day moving average, after adjusting for ozone. There was an 8.5% decrease in risk in the multipollutant model, proportional to a decrease of SO{sub 2} concentrations. The results of this study suggest that residents of medium-sized Brazilian cities with characteristics similar to those of São José dos Campos probably have health problems due to exposure to air pollutants.

  13. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil

    Directory of Open Access Journals (Sweden)

    C.T. Amancio

    2012-11-01

    Full Text Available There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of pollutants, particulate matter, sulfur dioxide (SO2, ozone, temperature, and humidity were obtained from the São Paulo State Environmental Agency. Moving average models for 2 to 7 days were calculated by Poisson regression using the R software. Exposure to SO2 was analyzed using a unipollutant, bipollutant or multipollutant model adjusted for mean temperature and humidity. The relative risks with 95%CI were obtained and the percent decrease in risk was calculated. There were 1928 deaths with a daily mean (± SD of 1.05 ± 1.03 (range: 0-6. Exposure to SO2 was significantly associated with mortality due to circulatory disease: RR = 1.04 (95%CI = 1.01 to 1.06 in the 7-day moving average, after adjusting for ozone. There was an 8.5% decrease in risk in the multipollutant model, proportional to a decrease of SO2 concentrations. The results of this study suggest that residents of medium-sized Brazilian cities with characteristics similar to those of São José dos Campos probably have health problems due to exposure to air pollutants.

  14. Chemical ligand non-innocence in pyridine diimine Rh complexes

    NARCIS (Netherlands)

    Kooistra, T.M.; Hetterscheid, D.G.H.; Schwartz, E.; Knijnenburg, Q.; Budzelaar, P.H.M.; Gal, A.W.

    2004-01-01

    The formation and reactivity of pyridine diimine rhodium(l) alkyl complexes without beta-hydrogens (Me, Bz, CH2SiMe3) is described. In contrast to the corresponding cobalt complexes, the rhodium complexes could not be activated to polymerise ethene. Rh ethyl complexes could not be prepared. Examples

  15. Developing a Methodology Based on Action Learning to Facilitate the Adoption of ICT in Small and Medium-sized Companies in Costa Rica

    DEFF Research Database (Denmark)

    Nunez, Heilyn Camacho

    2010-01-01

    The aim of the thesis is to understand and explore better strategies to support the Small and Medium-sized companies sector in Costa Rica in the ICT adoption process. A strategy has been proposed which focuses on learning process and the interaction of university, industry and government (Triple...

  16. Towards a Service-Oriented Enterprise: The Design of a Cloud Business Integration Platform in a Medium-Sized Manufacturing Enterprise

    Science.gov (United States)

    Stamas, Paul J.

    2013-01-01

    This case study research followed the two-year transition of a medium-sized manufacturing firm towards a service-oriented enterprise. A service-oriented enterprise is an emerging architecture of the firm that leverages the paradigm of services computing to integrate the capabilities of the firm with the complementary competencies of business…

  17. Focus of B-to-B e-commerce initiatives and related benefits in manufacturing small- and medium-sized enterprises

    NARCIS (Netherlands)

    Elie, E.; Lefebvre, L.A.; Lefebvre, E.

    2007-01-01

    Empirical research into business-to-business e-commerce issues involving manufacturing small- and medium-sized enterprises (SMEs) is still embryonic. In an attempt to partially fill this gap, this paper presents empirical data from an electronic survey conducted among 96 manufacturing SMEs to

  18. Non-governmental organizations and the sustainability of small and medium-sized enterprises in Peru : an analysis of networks and discourses

    NARCIS (Netherlands)

    Castro Aponte, W.V.

    2013-01-01

      The importance of small and medium-sized enterprises (SMEs) in terms of employment and income generation has been recognized worldwide. In Peru, SMEs are responsible for 85% of the employment at the national level and they represent 98% of the total companies registered. Around 12% of SMEs,

  19. Towards a Guideline for Design of a Corporate Entrepreneurship Function for Business Development in Medium-Sized Technology-Based Companies

    NARCIS (Netherlands)

    Uittenbogaard, Boaz; Broens, Lute; Groen, Arend J.

    2005-01-01

    The speed with which global high-technology markets evolve makes companies recognize that an effective innovation process is the best way to guarantee competitiveness. However, when (medium-sized) companies then wish to set up a corporate entrepreneurship function to enhance business development

  20. Impact of Top Management Team on Firm Performance in Small and Medium-Sized Enterprises Adopting Commercial Open-Source Enterprise Resource Planning

    Science.gov (United States)

    Cereola, Sandra J.; Wier, Benson; Norman, Carolyn Strand

    2012-01-01

    Based on the large number of small and medium-sized enterprises (SMEs) in the United States, their increasing interest in enterprise-wide software systems and their impact on the US economy, it is important to understand the determinants that can facilitate the successful implementation and assimilation of such technology into these firms' daily…

  1. Non-financial constraints to scaling-up small and medium-sized energy enterprises: Findings from field research in Ghana, Senegal, Tanzania and Zambia

    DEFF Research Database (Denmark)

    Haselip, James Arthur; Desgain, Denis DR; Mackenzie, Gordon A.

    2015-01-01

    constraint to establishing and expanding local small and medium-sized energy businesses, a range of significant non-financial constraints were also identified. This article provides a critical evaluation of these non-financial constraints as they were encountered in Ghana, Senegal, Tanzania and Zambia, based...

  2. Visualization of chemical reaction dynamics: Toward understanding complex polyatomic reactions

    National Research Council Canada - National Science Library

    SUZUKI, Toshinori

    2013-01-01

    Polyatomic molecules have several electronic states that have similar energies. Consequently, their chemical dynamics often involve nonadiabatic transitions between multiple potential energy surfaces...

  3. The role of small and medium-sized high-tech enterprise in the formation of innovative potential of the Voronezh region

    Directory of Open Access Journals (Sweden)

    E. A. Shubina

    2016-01-01

    Full Text Available In modern conditions the region's sustainable development and economic growth is largely determined by its ability to implement innovations. One of the determining factors of long-term economic development of the territories, to date, is innovation. A mechanism to give impetus to the innovative development of the regions is to create effective small and medium-sized innovative enterprises. Voronezh region, like many Russian regions, has considerable potential for innovation, but usually it is not used efficiently or not used at all. The article deals with the concept and the need to develop innovative entrepreneurship and the role of small and medium innovative enterprises in the formation of scientific and technical potential of the Voronezh region. The basic conditions and factors promoting and impeding the development of small and medium innovative businesses in the region, determined the willingness of subjects of innovation activity in the development, implementation and promotion of innovation in the region. The problems of development of small and medium-sized businesses at the regional level. The evaluation of actions to improve SMEs management programs in the region. Particular attention is given to the classification of small and medium-sized innovative business structures. In order to stimulate the development of small and medium-sized innovative business in the Voronezh region in the article suggests the implementation of a package of measures. The active use of innovation by small and medium-sized enterprises of the Voronezh area enhances their efficiency and competitiveness, creates new jobs, which ultimately has a positive effect on the region's economic development, the growth of the tax base, improving the quality of life of the population.

  4. Public Procurement as an Instrument for the Development of Small and Medium-Sized Business in Russia

    Directory of Open Access Journals (Sweden)

    Gulnara Talgatovna Gafurova

    2016-12-01

    Full Text Available The issue of the development of small and medium-sized business is relevant for many years. In the article, the questions of the support of small business through the system of public procurement are considered. Within this research, the authors have tried to systematize the data on the dynamics and structure of the public procurements from the point of view of the participation of small business in the purchasing process from the moment of the adoption of the Federal Public Contracts Act that allowed to reveal certain tendencies. The main methods of the research are the vertical and horizontal analysis of time series, the correlation and regression models of the panel data. The data on the participation of small business in the public procurements are grouped by various characteristics depending on the analysis purpose. The groups of the data have been analyzed on 83 entities of the Russian Federation. It has allowed making a full-scale estimation of the efficiency of procurements from the economics point of view. To estimate the influence of procurements on the development of small business entities, three hypotheses have been put forward: an increase in a number of customers placing orders for the small business enterprises, and a decrease in a share of the customers who are not meeting the requirements of the law about the threshold of 15 % lead to the growth of the budget savings; an increase in a number of demands for small business enterprises leads to the increase in the number of these enterprises in the regions; the number of the applications placed for small business entities influences the turnover of small enterprises. On the basis of the panel data of the unified information system of the central and local government procurement for the period of 2011–2015, econometric models confirming the hypotheses have been built. The authors’ calculations may be used by the authorities for the further development of measures for the

  5. Information and knowledge sharing trends of small and medium-sized enterprises in the Western Cape, South Africa

    Directory of Open Access Journals (Sweden)

    Faeda Mohsam

    2011-03-01

    Full Text Available Background: Small and medium-sized enterprises (SMEs, especially in the Western Cape Province of South Africa, are currently facing various financial and other obstacles, which may threaten their survival. Globalisation, the lowering of trade barriers and the reduction of import tariffs have resulted in increased international competition. Businesses are thus forced to undertake continuous improvements and innovation in order to survive, to keep abreast of change and to excel.Objectives: Effective knowledge sharing and consequent knowledge management (KM have been identified as definite approaches to enhancing competitive advantage. The research therefore aimed to establish to what extent small enterprises embrace their knowledge sharing activities and whether their knowledge sharing activities are managed at all. Furthermore, it examined how their knowledge sharing can contribute to their competitive advantage.Method: A case study approach was followed for this research. Selected SMEs from the engineering sector were the subject of the case study and SME owners, directors and managers of consulting civil engineering firms were interviewed to determine whether there are mechanisms in place to ensure better knowledge sharing within SMEs.Results: In general, respondents had stated that they possessed special factors that set them above their competitors:• The company strategy and good reputation of completing projects within the required timeframe. In other words, they were well known for their track record in terms of service delivery. • Their specialty in terms of different focus areas, namely structural and civil engineering, water supply and storm water design, transportation, sewer design and storm water traffic. • The fact that they operated in silos. This means that the specialists in their specific fields operated independently in groups, separately from everyone else in the company. • Their good relationship with local authorities

  6. Development of a Low NOx Medium sized Industrial Gas Turbine Operating on Hydrogen-Rich Renewable and Opportunity Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Srinivasan, Ram

    2013-07-31

    This report presents the accomplishments at the completion of the DOE sponsored project (Contract # DE-FC26-09NT05873) undertaken by Solar Turbines Incorporated. The objective of this 54-month project was to develop a low NOx combustion system for a medium sized industrial gas turbine engine operating on Hydrogen-rich renewable and opportunity Fuels. The work in this project was focused on development of a combustion system sized for 15MW Titan 130 gas turbine engine based on design analysis and rig test results. Although detailed engine evaluation of the complete system is required prior to commercial application, those tasks were beyond the scope of this DOE sponsored project. The project tasks were organized in three stages, Stages 2 through 4. In Stage 2 of this project, Solar Turbines Incorporated characterized the low emission capability of current Titan 130 SoLoNOx fuel injector while operating on a matrix of fuel blends with varying Hydrogen concentration. The mapping in this phase was performed on a fuel injector designed for natural gas operation. Favorable test results were obtained in this phase on emissions and operability. However, the resulting fuel supply pressure needed to operate the engine with the lower Wobbe Index opportunity fuels would require additional gas compression, resulting in parasitic load and reduced thermal efficiency. In Stage 3, Solar characterized the pressure loss in the fuel injector and developed modifications to the fuel injection system through detailed network analysis. In this modification, only the fuel delivery flowpath was modified and the air-side of the injector and the premixing passages were not altered. The modified injector was fabricated and tested and verified to produce similar operability and emissions as the Stage 2 results. In parallel, Solar also fabricated a dual fuel capable injector with the same air-side flowpath to improve commercialization potential. This injector was also test verified to produce 15

  7. Moving to business - changes in physical activity and sedentary behavior after multilevel intervention in small and medium-size workplaces.

    Science.gov (United States)

    Aittasalo, Minna; Livson, Matleena; Lusa, Sirpa; Romo, Ahti; Vähä-Ypyä, Henri; Tokola, Kari; Sievänen, Harri; Mänttäri, Ari; Vasankari, Tommi

    2017-04-17

    Regular physical activity (PA) promotes and excessive sedentary behavior (SB) deteriorates health. Yet the Finnish working-aged population spends most of the day sitting. A 1-year Moving To Business (MTB) -intervention supported small and medium-size workplaces to combat sedentariness. This paper reports the changes in employees' PA and SB from before MTB (baseline) to 1 year after baseline (follow-up). Twelve workplaces with a total of 396 employees participated. Each workplace nominated a team to promote PA and reduce SB at organizational, working unit and employee level. The teams were mentored regionally through meetings, workshop and tools. Changes in PA and SB were assessed with a questionnaire and an accelerometer. Wald Confidence Interval (Cl) for a difference of proportions with matched pairs was used in the questionnaire data (%-points with 95% CI) and linear mixed model in the accelerometer data (minutes and % of wear-time with 95% CI). The mean age of the respondents to the questionnaire (N = 296; 75%) was 42.6 (SD 10.9), 64% were women, 95% had some education after high school, 74% worked in the day shift, 71% did sedentary work and 51% were overweight. The mean number of actions implemented in the workplaces was 6.8 and the multilevel approach was fully applied in 6 workplaces. Based on the questionnaire the time spent in SB decreased from baseline to follow-up 16% (95% CI -29 to -3) in total and 22% (-41 to -3) at work. The accelerometer showed daily increases of 33.7 min (15.3 to 52.1) and 6.8% (3.1 to 10.4) in total PA, 30.9 min (15.3 to 46.5) and 6.1% (2.9 to 9.2) in light PA and 673 (209 to 1139) more steps at work. Daily SB at work decreased 44.9 min (-68.0 to -21.8) and 7.6% (-11.9 to -3.2). Daily leisure PA declined 11.0 min (-24.9 to 2.9) and 3.2% (-6.2 to -0.2). Number of levels or actions had no effect on changes. Employees' PA increased and SB reduced at work during the intervention. At the same time leisure PA decreased slightly

  8. Internationalisation Barriers of Small and Medium-sized Manufacturing Enterprises in Ethiopia: Leather and Leather Products Industry in Focus

    Directory of Open Access Journals (Sweden)

    Yehualashet Demeke Lakew

    2015-11-01

    Full Text Available The purpose of this study was to examine internationalisation barriers of manufacturing SMEs operating in Leather and Leather Products Industry located in the capital city of Ethiopia. The small and medium sized enterprises (SMEs sector in Ethiopia is a significant group within the economy in terms of firm numbers and total employment. However, the SMEs sector’s share of exports is disproportionately small, which raised considerable research concerns. Firm export propensity was the dependent variable and internal and external export barrier factors were used as explanatory variables. The study was conducted through mixed research design of quantitative survey and case study. From the population of manufacturing SMEs operating in the Leather and Leather products Industry, a sample was selected through the use of stratified random sampling to ensure the effective representation of the population of exporting and non-exporting SMEs in the capital of Ethiopia. In order to complement survey results nine (4 exporting and 5 non-exporting SMEs were selected through critical case purposive sampling and an in-depth interviews were conducted. Statistical package for the social sciences (SPSS 20 was used to analyse the quantitative data whereas, qualitative data were analysed manually. Exploratory factor analysis with Varimax rotation and Binary logistic regression analysis are the analytical methods used. The statistical result showed that, logistics problem, insufficient finance, functional barriers, lack of export knowledge and information, procedural barriers and international trade barriers are the most significant obstacles of export trade in Ethiopia. The overall results revealed that explanatory variables used in the analysis significantly predict the dependent variable at 95% confidence level. Taken together, these results prompted the presentation of numerous implications for theory, practice, and future research. Finally, the paper recommended

  9. Chemical solution deposition techniques for epitaxial growth of complex oxides

    NARCIS (Netherlands)

    ten Elshof, Johan E.; Koster, G.; Huijben, Mark; Rijnders, G.

    2015-01-01

    The chemical solution deposition (CSD) process is a wet-chemical process that is employed to fabricate a wide variety of amorphous and crystalline oxide thin films. This chapter describes the typical steps in a CSD process and their influence on the final microstructure and properties of films, and

  10. Algorithmic Complexity and Reprogrammability of Chemical Structure Networks

    KAUST Repository

    Zenil, Hector

    2018-02-16

    Here we address the challenge of profiling causal properties and tracking the transformation of chemical compounds from an algorithmic perspective. We explore the potential of applying a computational interventional calculus based on the principles of algorithmic probability to chemical structure networks. We profile the sensitivity of the elements and covalent bonds in a chemical structure network algorithmically, asking whether reprogrammability affords information about thermodynamic and chemical processes involved in the transformation of different compound classes. We arrive at numerical results suggesting a correspondence between some physical, structural and functional properties. Our methods are capable of separating chemical classes that reflect functional and natural differences without considering any information about atomic and molecular properties. We conclude that these methods, with their links to chemoinformatics via algorithmic, probability hold promise for future research.

  11. Chemical Warfare Agent Decontaminant Solution Using Quaternary Ammonium Complexes

    Science.gov (United States)

    1997-12-11

    warfare agents, which include a variety of organophosphorus and organosulfur compounds, are known in the art. 15 However, these known methods use...chemical warfare agents, and works particularly well for neutralization of organosulfur agents such as mustard gas (HD), and organophosphorus agents such...detoxifying/neutralizing a variety of chemical warfare agents, including organosulfur agents such as mustard gas (HD), and organophosphorus agents such as

  12. A Theory of Decomposition of Complex Chemical Networks using the Hill Functions

    CERN Document Server

    Chikayama, Eisuke

    2014-01-01

    The design and synthesis of complex and large mimicked biochemical networks de novo is an unsolved problem in synthetic biology. To address this limitation without resorting to ad hoc computations and experiments, a predictive mathematical theory is required to reduce these complex chemical networks into natural physico-chemical expressions. Here we provide a mathematical theory that offers a physico-chemical expression for a large chemical network that is almost arbitrarily both nonlinear and complex. Unexpectedly, the theory demonstrates that such networks can be decomposed into reactions based solely on the Hill equation, a simple chemical logic gate. This theory, analogous to implemented electrical logic gates or functional algorithms in a computer, is proposed for implementing regulated sequences of functional chemical reactions, such as mimicked genes, transcriptional regulation, signal transduction, protein interaction, and metabolic networks, into an artificial designed chemical network.

  13. Step-wise evolution of complex chemical defenses in millipedes: a phylogenomic approach.

    Science.gov (United States)

    Rodriguez, Juanita; Jones, Tappey H; Sierwald, Petra; Marek, Paul E; Shear, William A; Brewer, Michael S; Kocot, Kevin M; Bond, Jason E

    2018-02-16

    With fossil representatives from the Silurian capable of respiring atmospheric oxygen, millipedes are among the oldest terrestrial animals, and likely the first to acquire diverse and complex chemical defenses against predators. Exploring the origin of complex adaptive traits is critical for understanding the evolution of Earth's biological complexity, and chemical defense evolution serves as an ideal study system. The classic explanation for the evolution of complexity is by gradual increase from simple to complex, passing through intermediate "stepping stone" states. Here we present the first phylogenetic-based study of the evolution of complex chemical defenses in millipedes by generating the largest genomic-based phylogenetic dataset ever assembled for the group. Our phylogenomic results demonstrate that chemical complexity shows a clear pattern of escalation through time. New pathways are added in a stepwise pattern, leading to greater chemical complexity, independently in a number of derived lineages. This complexity gradually increased through time, leading to the advent of three distantly related chemically complex evolutionary lineages, each uniquely characteristic of each of the respective millipede groups.

  14. Health risk assessment of chemical pollutants in a petrochemical complex

    Directory of Open Access Journals (Sweden)

    F Golbabaie

    2012-12-01

    Full Text Available   Background and Aims: workers in petrochemical industries are exposed to various contaminants and are facing to serious hazards, therefore a comprehensive risk assessment program for identification of hazardous chemicals that affect human health and also determination of hazardous tasks and processes is necessary.     Methods : This descriptive cross-sectional study was conducted in three stages. First stage consisted of identifying hazardous chemicals and determination of chemicals risk ratio, the second stage included the evaluation of worker's exposure to hazardous chemicals, and the third stage was estimating the relative risk of blood cancer caused by exposure to benzene through epidemiological studies.     Results: With regard to risk assessment method, 40 chemicals were identified in this Petrochemical Company. Among them, Benzene introduced as the most hazardous chemical. The results of the second stage showed that site man workers in noon shift work and in aromatic site with mean exposure 4.29 ppm had the highest exposure to benzene. The results of estimated leukemia relative risk stage in benzene exposure, the highest relative risk in workers related to site man workers in aromatic units with cumulative benzene exposure of 4.149 ppm. Years that obtained the relative risk of 2.3. The statistical test results showed that the relationship between worker's exposure to benzene and their job was significant(p<0/001     Conclusion : This study showed that benzene with a risk ratio of 4.5 -5 have 5th rank in risk levels and this indicates that preventative actions regarding to this hazardous and carcinogenic chemical must be started as soon as possible.

  15. Physico-chemical studies of some aminobenzoic acid hydrazide complexes

    Directory of Open Access Journals (Sweden)

    S. ABD EL HALEEM

    2004-04-01

    Full Text Available The stability constants and related thermodynamic functions characterizing the formation of divalent Ni, Cu, Zn, Cd and Hg complexes with o- and p-aminobenzoic acid hydrazide were determined potentiometrically at different temperatures. The formations of the complexes are endothermic processes. The formed bonds are mainly electrostatic. Conductometric titration was carried out to determine the stoichiometry and stability of the formed complexes. The structures of complexes were characterized by their IR, 1H-NMR and 13C-NMR spectra, as well as X-ray diffractograms. The coordination process takes place through the carbonyl group and the terminal hydrazinic amino group. The thermal stability of the complexes was followed in the temperature range 20–600ºC.

  16. An Empirical Study of IT Innovation Adoption Among Small and Medium Sized Enterprises in Klang Valley, Malaysia

    Directory of Open Access Journals (Sweden)

    Wenjie Zhao

    2011-12-01

    Full Text Available Purpose—The purpose of this research is to use and validate the Entrepreneurial Event model as a base model to investigate SME owners’ perception toward IT innovation adoption and use. This paper also attempts to investigate the key determinants of the adoption of IT innovation among small and medium sized enterprises in Kuala Lumpur, Malaysia. This study revised and validated the Entrepreneurial Event Model in a new context and tried to examine the effect of perceived desirability, propensity to act and performance expectancy on behavior intention to adopt and use IT innovation in SMEs companies.Design/ methodology/ approach—Based on the research model the questionnaire was developed using previous work in the areas of entrepreneurship (Entrepreneurial Event Model and technology acceptance (UTAUT. The data used to test the hypothesis is collectedfrom various spectrums of Malaysian industries in Kuala Lumpur. A total of 1,000 businesses were identified and 412 completed questionnaires were available in this study. The research model was applied using the structural equation modelling technique.Finding—The results of this study indicated that perceived desirability, propensity to act and performance expectancy have a significant positive influence on behavioral intention, and explained a significant amount of the variance in predicting a SMEs owners intention to adopt IT innovation. Propensity to act is the strongest determinant of intention to use IT innovations among Malaysian SME owners follow by perceived desirability and performance expectancy. The results suggest that attractiveness of IT innovation is an important determinant towards the intention to adopt IT innovation. The result revealed that SME owners are more willing to use IT innovation, which is more attractive. Perceived usefulness (performance expectancy of IT innovation is the third most important factor that SME owners consider when they want to adopt and use new

  17. An Empirical Study of IT Innovation Adoption Among Small and Medium Sized Enterprises in Klang Valley, Malaysia

    Directory of Open Access Journals (Sweden)

    Sedigheh Moghavvemi

    2013-08-01

    Full Text Available Purpose—The purpose of this research is to use and validate the Entrepreneurial Event model as a base model to investigate SME owners’ perception toward IT innovation adoption and use. This paper also attempts to investigate the key determinants of the adoption of IT innovation among small and medium sized enterprises in Kuala Lumpur, Malaysia. This study revised and validated the Entrepreneurial Event Model in a new context and tried to examine the effect of perceived desirability, propensity to act and performance expectancy on behavior intention to adopt and use IT innovation in SMEs companies. Design/ methodology/ approach—Based on the research model the questionnaire was developed using previous work in the areas of entrepreneurship (Entrepreneurial Event Model and technology acceptance (UTAUT. The data used to test the hypothesis is collected from various spectrums of Malaysian industries in Kuala Lumpur. A total of 1,000 businesses were identified and 412 completed questionnaires were available in this study. The research model was applied using the structural equation modelling technique. Finding—The results of this study indicated that perceived desirability, propensity to act and performance expectancy have a significant positive influence on behavioral intention, and explained a significant amount of the variance in predicting a SMEs owners intention to adopt IT innovation. Propensity to act is the strongest determinant of intention to use IT innovations among Malaysian SME owners follow by perceived desirability and performance expectancy. The results suggest that attractiveness of IT innovation is an important determinant towards the intention to adopt IT innovation. The result revealed that SME owners are more willing to use IT innovation, which is more attractive. Perceived usefulness (performance expectancy of IT innovation is the third most important factor that SME owners consider when they want to adopt and use new

  18. Evaluation of the Decree on Emission Regulations for Medium-sized Combustion Installations; Evaluatie Besluit emissie-eisen middelgrote stookinstallaties

    Energy Technology Data Exchange (ETDEWEB)

    Kroon, P.; Plomp, A.J. [ECN Beleidsstudies, Petten (Netherlands); Van Berkel, L.; Burgers, W.; Hermans, L.; Groot, M.; Simonse, W. [Kenniscentrum InfoMil, Rijkswaterstaat Water, Verkeer en Leefomgeving, Den Haag (Netherlands); Kruithof, P.; Taal, M.; Van Bergen, J.; Walthaus, H. [Ministerie van Infrastructuur en Milieu IenM, Den Haag (Netherlands)

    2013-05-15

    In April 2010 the Dutch decree on emission limit values (ELVs) on medium-sized combustion installations entered into force. Bems sets ELVs for NOx, SO2, PM and CxHy. In 2013 the Bems legislation was transferred to the Activities Decree (In Dutch: Ab - Activiteitenbesluit). At the same time the Industrial Emissions Directive (IED) was implemented in the Ab. At the time Bems entered into force, it was decided to evaluate this legislation in 2014. Due to incorporation of Bems and the implementation of the IED in the Ab, it was decided to perform this evaluation a year earlier, thereby enabling the consideration of several stakeholders' comments on these implementations. This report presents the main conclusions of this evaluation. In Bems, combustion installations smaller than 50 MWth have to comply with ELVs based on Best Available Technology (BAT). Five possible ELVs have been discussed but not implemented in Bems, due to a lack of knowledge. These ELVs have been included in this evaluation. For gas engines < 2.5 MWth the NOx ELV could be more stringent, namely 140 mg/Nm{sup 3} instead of 340 mg/Nm{sup 3}; all ELVs are set at dry conditions in the flue gas and 3% O2. For biogas engines, introduction of the same ELV might be postponed until a comparable ELV enters into force in 2016 in a Californian region. Both the Californian ELV and this ELV need a gas cleaning technology. For (bio)diesel engines the dust ELV could be more stringent, namely 15 mg PM/Nm{sup 3} instead of 50 mg PM/Nm{sup 3}, while for NOx the ELV can be tightened from 450 mg/Nm{sup 3} to 250 mg/Nm{sup 3}. Both ELVs may be postponed until Tier 4 limits in the USA enter into force in the period 2014-2017. The Netherlands is one of the very few countries with CxHy ELVs for gas engines. The current CxHy ELV of 1500 mg C/Nm{sup 3} may be tightened to 1200 mg C/Nm{sup 3}. Other issues and changes, directly related to the Dutch legislation, have been discussed as well. These include exemption rules

  19. IMPACT OF THE IMPLEMENTATION OF QUALITY MANAGEMENT SYSTEM ON OPERATING COST FOR SMALL AND MEDIUM - SIZED BUSINESS ORGANIZATIONS AFFILIATED TO A PURCHASING GROUP

    Directory of Open Access Journals (Sweden)

    Dominik Zimon

    2015-12-01

    Full Text Available Purpose - The purpose of this paper is to ask one question. How the implementation of the requirements of ISO 9001 system affects the costs of running the business? Design/methodology/approach - The research covered time from 2006 to 2011 and was an attempt to assess the impact of the maintenance of the ISO 9001 Quality Management System on the costs of small and medium sized business organizations. The main objective was the selection of right research subjects that would allow the formulation of the most reliable and statistically valid conclusions. For this purpose we obtained permissions to conduct research in organizations characterized by comparable futures such as size, industry, type of business and strategy. Findings - The study shows that the costs associated with the implementation and maintenance of the Quality Management System standard is still too high, and effectively discourages representatives of small and medium-sized commercial organizations from implementing ISO 9001 system.

  20. The impact of work experience of small and medium-sized enterprises owners or managers on their competitive intelligence awareness and practices

    Directory of Open Access Journals (Sweden)

    Rene Pellissier

    2013-06-01

    Objectives: The objective of this research was to establish the influence of owners’ and managers' working experience of CI practice and awareness in the small and medium-sized enterprises (SMEs environment. Method: This research was quantitative in nature and a questionnaire was used to collect data from SMEs owners and managers in The City of Tshwane Metropolitan Municipality. Results: This research indicates that SMEs in the study are aware of CI through education and training. Moreover, the study reveals that the working experience of owners and managers has a great influence on awareness and practice of CI and one should implement training programmes in this domain to assist with building competitive advantage. Conclusion: Small and medium-sized enterprises owners or managers’ years of working experience has a greater influence on awareness and practice of CI. Put differently, years of working experience is a great predictor of CI awareness and practice.

  1. MANAGING IT SERVICES AS A SOURCE OF INNOVATION IN SMALL AND MEDIUM-SIZED ENTERPRISES OF THE ICT SECTOR IN POLAND

    Directory of Open Access Journals (Sweden)

    Magdalena Ciesielska

    2017-12-01

    Full Text Available Efficient IT service management is a current area of concern and the focus of on-going improvement for both business and science. The high dynamics of the software market, globalisation and delivery of high quality IT services are challenges that small and medium-sized enterprises must face. The drive towards innovation in the SME sector cannot concentrate only on the product but also on the process and organization. ITSM frameworks and good industry practices are an effective tool to help support innovation in providing IT services. This article aims to identify barriers to and benefits of ITSM implementation in SMEs of the Polish ICT sector and interpret the obtained results in the context of creating innovation. The article present the results of primary data collection among 345 small and medium-sized enterprises of the ICT sector in Poland.

  2. Development of a Growth Strategy for Small- and Medium-Sized Enterprises and Derived, Selected Recomendations for Action : Principles, Concept and Methodology by Means of a Practical Example

    OpenAIRE

    Bauer, Svenja

    2016-01-01

    The aim of this thesis is to research and present common concepts and method-ologies of strategic management against the background of developing a growth strategy for small- and medium-sized enterprises. The theories, which are elabo-rated in the first part of this thesis will be applied on a German company operating in the fitness market. Therefore, customer surveys and interviews with the man-agement are used to provide highly-qualitative market information.

  3. For the Good of All : Integrating corporate social responsibility into the business strategy of small and medium sized enterprises in Finland: CASE: Oy Vallila Interior Ab

    OpenAIRE

    Anttila, Hannele

    2010-01-01

    Corporate social responsibility (CSR) can be defined as a concept that includes simultaneous fulfilment of a company’s economic, legal, ethical and philanthropic responsibilities, as well as companies integrating social and environmental concerns in their business operations and in their interaction with their stakeholders on a voluntary basis. The purpose of this dissertation is to investigate CSR from the perspective of small and medium sized enterprises (SMEs), more specifically from t...

  4. An Assessment of the Influence of Selected on the Performance of Small to Medium Sized Family Owned Businesses in the Zimbabwe Retail Sector

    OpenAIRE

    Maxwell Sandada; Lorraine Mangwandi

    2015-01-01

    The study attempted to assess the factors that are affecting business performance of small to medium sized family owned businesses in the Zimbabwean retail sector. The objective was to establish the effect of innovation, management skills, succession planning and corporate governance on family owned SMEs in Zimbabwe. The study sought to complement other previous studies that were carried out in other different contexts by producing evidence on the same phenomenon from a developing...

  5. First-visit patients without a referral to the Department of Internal Medicine at a medium-sized acute care hospital in Japan: an observational study

    OpenAIRE

    Kajiwara, Nobuyuki; Hayashi, Kazuyuki; Misago, Masahiro; Murakami, Shinichiro; Ueoka, Takato

    2017-01-01

    Nobuyuki Kajiwara,1 Kazuyuki Hayashi,1 Masahiro Misago,2 Shinichiro Murakami,2 Takato Ueoka2 1Department of Nephrology, Ikeda City Hospital, 2Department of General Medicine, Ikeda City Hospital, Johnan, Osaka, Japan Purpose: We sought to profile first-time patients without a referral who sought medical care at the Department of Internal Medicine at a medium-sized acute care hospital in Japan. We anticipated that the analysis would highlight the demand for medical care needs from acute care ho...

  6. The adoption of e-commerce in small and medium-sized enterprises in Vietnam : recommendations for building an e-commerce strategy

    OpenAIRE

    Ho, Huong

    2013-01-01

    It is highly recommended for small and medium-sized enterprises (SMEs) to integrate e-commerce into their business operations because it is an opportunity to increase profitability, enhance effectiveness, and increase corporate values. However, the number of Vietnamese SMEs adopting e-commerce is insignificant due to lack of understanding of the process of integrating it into business operations. This research is conducted for the purpose of providing SMEs attempting to move towards the e-com...

  7. Non-governmental organizations and the sustainability of small and medium-sized enterprises in Peru : an analysis of networks and discourses

    OpenAIRE

    Castro Aponte, W.V.

    2013-01-01

      The importance of small and medium-sized enterprises (SMEs) in terms of employment and income generation has been recognized worldwide. In Peru, SMEs are responsible for 85% of the employment at the national level and they represent 98% of the total companies registered. Around 12% of SMEs, organized in associations, clusters, and cooperatives or as single companies, are dedicated to productive actives; the others are engaged in commercial and services activities. However, next to thei...

  8. Focus of B-to-B e-commerce initiatives and related benefits in manufacturing small- and medium-sized enterprises

    OpenAIRE

    Elie, E.; Lefebvre, L.A.; Lefebvre, E.

    2007-01-01

    Empirical research into business-to-business e-commerce issues involving manufacturing small- and medium-sized enterprises (SMEs) is still embryonic. In an attempt to partially fill this gap, this paper presents empirical data from an electronic survey conducted among 96 manufacturing SMEs to investigate e-commerce initiatives and their related benefits. E-commerce initiatives are assessed using a set of 36 business processes that can be conducted electronically. These processes were classifi...

  9. FINANCING OPTIONS FOR SMALL AND MEDIUM-SIZED ENTERPRISES (SMES) : EXPLORING NON-BANK FINANCIAL INSTITUTIONS AS AN ALTERNATIVE MEANS OF FINANCING

    OpenAIRE

    LEMUEL, ESISAL-RUTH

    2009-01-01

    ABSTRACT BACKGROUND AND PROBLEM DISCUSSION: Small and medium-sized enterprises are observed as capable instruments to solving the critical problems of development and poverty affecting most developing countries (Kayanula and Quartey 2000; Mead and Liedholm 1998; Fischer 1995), therefore the need for their growth in Nigeria is beyond question. Amidst many other problems, gaining access to bank credits and other financial markets have been identified as a key hindrance to this growth. This thes...

  10. Methylene Diphosphonate Chemical and Biological control of MDP complex

    CERN Document Server

    Aungurarat, A

    2000-01-01

    Technetium-9 sup 9 sup m MDP easy prepared from MDP kits which different sources such as OAP (In house), SIGMA. The resulting Tc 9 sup 9 sup m -MDP preparations were controlled in chemical and biological tests to compare the different results in these cases: radiochemical purity, the quantity of starting material and biodistribution result.

  11. Use of care management practices in small- and medium-sized physician groups: do public reporting of physician quality and financial incentives matter?

    Science.gov (United States)

    Alexander, Jeffrey A; Maeng, Daniel; Casalino, Lawrence P; Rittenhouse, Diane

    2013-04-01

    To examine the effect of public reporting (PR) and financial incentives tied to quality performance on the use of care management practices (CMPs) among small- and medium-sized physician groups. Survey data from The National Study of Small and Medium-sized Physician Practices were used. Primary data collection was also conducted to assess community-level PR activities. The final sample included 643 practices engaged in quality reporting; about half of these practices were subject to PR. We used a treatment effects model. The instrumental variables were the community-level variables that capture the level of PR activity in each community in which the practices operate. (1) PR is associated with increased use of CMPs, but the estimate is not statistically significant; (2) financial incentives are associated with greater use of CMPs; (3) practices' awareness/sensitivity to quality reports is positively related to their use of CMPs; and (4) combined PR and financial incentives jointly affect CMP use to a greater degree than either of these factors alone. Small- to medium-sized practices appear to respond to PR and financial incentives by greater use of CMPs. Future research needs to investigate the appropriate mix and type of incentive arrangements and quality reporting. © Health Research and Educational Trust.

  12. Distribution of Complex Chemicals in Oil-Water Systems

    DEFF Research Database (Denmark)

    Riaz, Muhammad

    The deepwater energy sector represents one of the major growth areas of the oil and gas industry today. In order to meet the challenges of hydrate formation, corrosion, scaling and foaming the oil and gas industry uses many chemicals and their use has increased significantly over the years....... In order to inhibit gas hydrate formation in subsea pipelines monoethylene glycol (MEG) and methanol are injected in large amounts. It is important to know the distribution of these chemicals in oil and water systems for economical operation of a production facility and to evaluate their impact on marine...... of ill-defined components in decane plus fraction. When methanol and MEG are used as gas hydrate inhibitors, the most significant disadvantage, especially for methanol, is their loss in hydrocarbon phase(s). The successful estimation of inhibitor loss would enable the inhibitors injection optimization...

  13. Kojak: efficient analysis of chemically cross-linked protein complexes.

    Science.gov (United States)

    Hoopmann, Michael R; Zelter, Alex; Johnson, Richard S; Riffle, Michael; MacCoss, Michael J; Davis, Trisha N; Moritz, Robert L

    2015-05-01

    Protein chemical cross-linking and mass spectrometry enable the analysis of protein-protein interactions and protein topologies; however, complicated cross-linked peptide spectra require specialized algorithms to identify interacting sites. The Kojak cross-linking software application is a new, efficient approach to identify cross-linked peptides, enabling large-scale analysis of protein-protein interactions by chemical cross-linking techniques. The algorithm integrates spectral processing and scoring schemes adopted from traditional database search algorithms and can identify cross-linked peptides using many different chemical cross-linkers with or without heavy isotope labels. Kojak was used to analyze both novel and existing data sets and was compared to existing cross-linking algorithms. The algorithm provided increased cross-link identifications over existing algorithms and, equally importantly, the results in a fraction of computational time. The Kojak algorithm is open-source, cross-platform, and freely available. This software provides both existing and new cross-linking researchers alike an effective way to derive additional cross-link identifications from new or existing data sets. For new users, it provides a simple analytical resource resulting in more cross-link identifications than other methods.

  14. Computing distance-based topological descriptors of complex chemical networks: New theoretical techniques

    Science.gov (United States)

    Hayat, Sakander

    2017-11-01

    Structure-based topological descriptors/indices of complex chemical networks enable prediction of physico-chemical properties and the bioactivities of these compounds through QSAR/QSPR methods. In this paper, we have developed a rigorous computational and theoretical technique to compute various distance-based topological indices of complex chemical networks. A fullerene is called the IPR (Isolated-Pentagon-Rule) fullerene, if every pentagon in it is surrounded by hexagons only. To ensure the applicability of our technique, we compute certain distance-based indices of an infinite family of IPR fullerenes. Our results show that the proposed technique is more diverse and bears less algorithmic and combinatorial complexity.

  15. CALCULATION OF CHEMICAL ATMOSPHERE ESTIMATION GIVEN THE COMPLEX TERRAIN

    Directory of Open Access Journals (Sweden)

    M. M. Biliaiev

    2010-06-01

    Full Text Available The 3D numerical model was used to simulate the toxic gas dispersion over a complex terrain after an accident spillage. The model is based on the K-gradient transport model and the model of potential flow. The results of numerical experiment are presented.

  16. Chemical Synthesis of Complex Molecules Using Nanoparticle Catalysis

    OpenAIRE

    Cong, Huan; Porco, John A.

    2012-01-01

    Nanoparticle catalysis has emerged as an active topic in organic synthesis. Of particular interest is the development of enabling methodologies to efficiently assemble complex molecules using nanoparticle catalysis. This Viewpoint highlights recent developments and discusses future perspectives in this emerging field.

  17. Physico-chemical studies on vanadyl complexes of some tridentates

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, K.G.; Mathur, R.P.; Mehta, R.K. (Jodhpur Univ. (India). Dept. of Chemistry)

    1981-05-01

    The vanadyl complexes of the type (VO.L.(H/sub 2/O)/sub 2/) were synthesised with 3-(..cap alpha..-benzoylmethyl-benzylideneimino) propanoic acid (H/sub 2/BP), O-(..cap alpha..-benzoylmethyl-benzylideneimino) benzoic acid (H/sub 2/BB) and (..cap alpha..-benzoylmethyl-benzylideneimino) benzene sulphonic acid (H/sub 2/BBS). These complexes have been studied potentiometrically in aqueous medium (..mu..=0.1, 0.05 and 0.01 M NaClO/sub 4/) at 25deg, 35deg and 45deg C. The solid chelates have also been synthesised and characterised by elemental analysis, molecular weight, magnetic, conductance and spectral techniques.

  18. From Molecules to Life: Quantifying the Complexity of Chemical and Biological Systems in the Universe.

    Science.gov (United States)

    Böttcher, Thomas

    2017-12-19

    Life is a complex phenomenon and much research has been devoted to both understanding its origins from prebiotic chemistry and discovering life beyond Earth. Yet, it has remained elusive how to quantify this complexity and how to compare chemical and biological units on one common scale. Here, a mathematical description of molecular complexity was applied allowing to quantitatively assess complexity of chemical structures. This in combination with the orthogonal measure of information complexity resulted in a two-dimensional complexity space ranging over the entire spectrum from molecules to organisms. Entities with a certain level of information complexity directly require a functionally complex mechanism for their production or replication and are hence indicative for life-like systems. In order to describe entities combining molecular and information complexity, the term biogenic unit was introduced. Exemplified biogenic unit complexities were calculated for ribozymes, protein enzymes, multimeric protein complexes, and even an entire virus particle. Complexities of prokaryotic and eukaryotic cells, as well as multicellular organisms, were estimated. Thereby distinct evolutionary stages in complexity space were identified. The here developed approach to compare the complexity of biogenic units allows for the first time to address the gradual characteristics of prebiotic and life-like systems without the need for a definition of life. This operational concept may guide our search for life in the Universe, and it may direct the investigations of prebiotic trajectories that lead towards the evolution of complexity at the origins of life.

  19. Chemical bonding of hydrogen molecules to transition metal complexes

    Energy Technology Data Exchange (ETDEWEB)

    Kubas, G.J.

    1990-01-01

    The complex W(CO){sub 3}(PR{sub 3}){sub 2}(H{sub 2}) (CO = carbonyl; PR{sub 3} = organophosphine) was prepared and was found to be a stable crystalline solid under ambient conditions from which the hydrogen can be reversibly removed in vacuum or under an inert atmosphere. The weakly bonded H{sub 2} exchanges easily with D{sub 2}. This complex represents the first stable compound containing intermolecular interaction of a sigma-bond (H-H) with a metal. The primary interaction is reported to be donation of electron density from the H{sub 2} bonding electron pair to a vacant metal d-orbital. A series of complexes of molybdenum of the type Mo(CO)(H{sub 2})(R{sub 2}PCH{sub 2}CH{sub 2}PR{sub 2}){sub 2} were prepared by varying the organophosphine substitutent to demonstrate that it is possible to bond either dihydrogen or dihydride by adjusting the electron-donating properties of the co-ligands. Results of infrared and NMR spectroscopic studies are reported. 20 refs., 5 fig.

  20. An Investigation of Electronic Structure and Aromaticity in Medium-Sized Nanoclusters of Gold-Doped Germanium

    Directory of Open Access Journals (Sweden)

    Xiao-Jun Li

    2012-01-01

    Full Text Available The electronic property and aromaticity of endohedrally doped and clusters are investigated using the density-functional theory (DFT within the hybrid B3LYP method. The calculated results reveal that the two clusters have high thermodynamic stability reflected by reaction energy. At the same time, it could be hoped that their high stability may arise from the closed-shell spherical aromaticity with eight -electrons satisfying the counting rule with . A popular nucleus-independent chemical shifts (NICSs calculation on basis of magnetic shieldings is also performed to confirm the aromaticity of the three-dimensional nanoclusters with largely negative NICS values. In addition, the electronic features and chemical bonding of the two clusters are analyzed with the help of the density of states (DOS and electron localization function (ELF, and the majority of Ge–Ge bonds on the cage show more covalent characters.

  1. Intermittent Plurisink Model and the Emergence of Complex Heterogeneity Patterns: A Simple Paradigm for Explaining Complexity in Soil Chemical Distributions

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Martín

    2015-01-01

    Full Text Available The spatial complexity of the distribution of organic matter, chemicals, nutrients, and pollutants has been demonstrated to have multifractal nature. This fact supports the possibility of existence of some emergent heterogeneity structure built under the evolution of the system. The aim of this paper is providing a consistent explanation of the mentioned results via an extremely simple model.

  2. Building structural complexity in semiconductor nanocrystals through chemical transformations

    Science.gov (United States)

    Sadtler, Bryce Frederick

    2009-08-01

    Methods are presented for synthesizing nanocrystal heterostructures comprised of two semiconductor materials epitaxially attached within individual nanostructures. The chemical transformation of cation exchange, where the cations within the lattice of an ionic nanocrystal are replaced with a different metal ion species, is used to alter the chemical composition at specific regions of a nanocrystal. Partial cation exchange was performed in cadmium sulfide (CdS) nanorods of well-defined size and shape to examine the spatial organization of materials within the resulting nanocrystal heterostructures. The selectivity for cation exchange to take place at different facets of the nanocrystal plays an important role in determining the resulting morphology of the binary heterostructure. The exchange of copper (I) (Cu+) cations in CdS nanorods occurs preferentially at the ends of the nanorods. Theoretical modeling of epitaxial attachments between different facets of CdS and Cu2S indicate that the selectivity for cation exchange at the ends of the nanorods is a result of the low formation energy of the interfaces produced. During silver (I) (Ag+) cation exchange in CdS nanorods, non-selective nucleation of silver sulfide (Ag2S), followed by partial phase segregation leads to significant changes in the spatial arrangement of CdS and Ag2S regions at the exchange reaction proceeds through the nanocrystal. A well-ordered striped pattern of alternating CdS and Ag 2S segments is found at intermediate fractions of exchange. The forces mediating this spontaneous process are a combination of Ostwald ripening to reduce the interfacial area along with a strain-induced repulsive interaction between Ag2S segments. To elucidate why Cu+ and Ag+ cation exchange with CdS nanorods produce different morphologies, models for epitaxial attachments between various facets of CdS with Cu2S or Ag2S lattices were used to calculate interface formation energies. The formation energies indicate the

  3. Computational Analyses of Complex Flows with Chemical Reactions

    Science.gov (United States)

    Bae, Kang-Sik

    The heat and mass transfer phenomena in micro-scale for the mass transfer phenomena on drug in cylindrical matrix system, the simulation of oxygen/drug diffusion in a three dimensional capillary network, and a reduced chemical kinetic modeling of gas turbine combustion for Jet propellant-10 have been studied numerically. For the numerical analysis of the mass transfer phenomena on drug in cylindrical matrix system, the governing equations are derived from the cylindrical matrix systems, Krogh cylinder model, which modeling system is comprised of a capillary to a surrounding cylinder tissue along with the arterial distance to veins. ADI (Alternative Direction Implicit) scheme and Thomas algorithm are applied to solve the nonlinear partial differential equations (PDEs). This study shows that the important factors which have an effect on the drug penetration depth to the tissue are the mass diffusivity and the consumption of relevant species during the time allowed for diffusion to the brain tissue. Also, a computational fluid dynamics (CFD) model has been developed to simulate the blood flow and oxygen/drug diffusion in a three dimensional capillary network, which are satisfied in the physiological range of a typical capillary. A three dimensional geometry has been constructed to replicate the one studied by Secomb et al. (2000), and the computational framework features a non-Newtonian viscosity model for blood, the oxygen transport model including in oxygen-hemoglobin dissociation and wall flux due to tissue absorption, as well as an ability to study the diffusion of drugs and other materials in the capillary streams. Finally, a chemical kinetic mechanism of JP-10 has been compiled and validated for a wide range of combustion regimes, covering pressures of 1atm to 40atm with temperature ranges of 1,200 K--1,700 K, which is being studied as a possible Jet propellant for the Pulse Detonation Engine (PDE) and other high-speed flight applications such as hypersonic

  4. Building Structural Complexity in Semiconductor Nanocrystals through Chemical Transformations

    Energy Technology Data Exchange (ETDEWEB)

    Sadtler, Bryce F [Univ. of California, Berkeley, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2009-05-01

    Methods are presented for synthesizing nanocrystal heterostructures comprised of two semiconductor materials epitaxially attached within individual nanostructures. The chemical transformation of cation exchange, where the cations within the lattice of an ionic nanocrystal are replaced with a different metal ion species, is used to alter the chemical composition at specific regions ofa nanocrystal. Partial cation exchange was performed in cadmium sulfide (CdS) nanorods of well-defined size and shape to examine the spatial organization of materials within the resulting nanocrystal heterostructures. The selectivity for cation exchange to take place at different facets of the nanocrystal plays an important role in determining the resulting morphology of the binary heterostructure. The exchange of copper (I) (Cu+) cations in CdS nanorods occurs preferentially at the ends of the nanorods. Theoretical modeling of epitaxial attachments between different facets of CdS and Cu2S indicate that the selectivity for cation exchange at the ends of the nanorods is a result of the low formation energy of the interfaces produced. During silver (I) (Ag+) cation exchange in CdS nanorods, non-selective nucleation of silver sulfide (Ag2S), followed by partial phase segregation leads to significant changes in the spatial arrangement of CdS and Ag2S regions at the exchange reaction proceeds through the nanocrystal. A well-ordered striped pattern of alternating CdS and Ag2S segments is found at intermediate fractions of exchange. The forces mediating this spontaneous process are a combination of Ostwald ripening to reduce the interfacial area along with a strain-induced repulsive interaction between Ag2S segments. To elucidate why Cu+ and Ag+ cation exchange with CdS nanorods produce different morphologies, models for epitaxial attachments between various facets of CdS with Cu2S or

  5. Relative impact of on-road vehicular and point-source industrial emissions of air pollutants in a medium-sized Andean city

    Science.gov (United States)

    González, C. M.; Gómez, C. D.; Rojas, N. Y.; Acevedo, H.; Aristizábal, B. H.

    2017-03-01

    Cities in emerging countries are facing a fast growth and urbanization; however, the study of air pollutant emissions and its dynamics is scarce, making their populations vulnerable to potential effects of air pollution. This situation is critical in medium-sized urban areas built along the tropical Andean mountains. This work assesses the contribution of on-road vehicular and point-source industrial activities in the medium-sized Andean city of Manizales, Colombia. Annual fluxes of criteria pollutants, NMVOC, and greenhouse gases were estimated. Emissions were dominated by vehicular activity, with more than 90% of total estimated releases for the majority of air pollutants. On-road vehicular emissions for CO (43.4 Gg/yr) and NMVOC (9.6 Gg/yr) were mainly associated with the use of motorcycles (50% and 81% of total CO and NMVOC emissions respectively). Public transit buses were the main source of PM10 (47%) and NOx (48%). The per-capita emission index was significantly higher in Manizales than in other medium-sized cities, especially for NMVOC, CO, NOx and CO2. The unique mountainous terrain of Andean cities suggest that a methodology based on VSP model could give more realistic emission estimates, with additional model components that include slope and acceleration. Food and beverage facilities were the main contributors of point-source industrial emissions for PM10 (63%), SOx (55%) and NOx (45%), whereas scrap metal recycling had high emissions of CO (73%) and NMVOC (47%). Results provide the baseline for ongoing research in atmospheric modeling and urban air quality, in order to improve the understanding of air pollutant fluxes, transport and transformation in the atmosphere. In addition, this emission inventory could be used as a tool to identify areas of public health exposure and provide information for future decision makers.

  6. Consumption and conservation of energy in small and medium-size business, trade, and the service industry; Energieverbrauch und Einsparung in Gewerbe, Handel und Dienstleistung

    Energy Technology Data Exchange (ETDEWEB)

    Geiger, B. [Technische Univ. Muenchen (Germany). Lehrstuhl fuer Energiewirtschaft und Kraftwerkstechnik; Gruber, E. [Fraunhofer-Institut fuer Systemtechnik und Innovationsforschung (ISI), Karlsruhe (Germany); Megele, W. [Forschungsstelle fuer Energiewirtschaft, Muenchen (Germany)

    1999-07-01

    The book presents a wealth of information and topical findings compiled in a database, relating to energy consumption by small and medium-sized business in Germany, describing energy consumption patterns in a crosscut survey of business activities characterized by a great technological variety. Based on results obtained from investigations performed in selected enterprises, a questionnaire has been formulated and distributed to almost 3 000 establishments, collecting information on their energy consumption, their installed energy technology, and their activities and equipment for energy conservation. The book presents entirely new information on energy consumption patterns of small and medium-sized business not considered so far by relevant research activities, and gives detailed information and extrapolated results permitting a comparative analysis of particular branches of business, as e.g. the motor vehicle trade, the baker's trade, agriculture, retail trade, hotels, public administration. The latest available survey on energy consumption patterns of small and the medium-sized industry dates back to 1982, and did not consider energy conservation measures or technology. (orig./CB) [German] Eine Fuelle von Ergebnissen und Erkenntnissen zum Energieverbrauch und zur Aufschluesselung nach Energietraegern und Verwendungszwecken in dem technologisch sehr vielfaeltigen und in der Forschung bisher vernachlaessigten Sektor 'Kleinverbrauch' auf einer aktuellen Datenbasis liegt jetzt mit diesem Buch vor. Dazu wurden, nach vorangegangenen betrieblichen Einzeluntersuchungen, knapp 3.000 Betriebe zum Energieverbrauch, zum Stand der energietechnischen Ausstattung und ihrer Energiesparaktivitaeten befragt. Das Buch stellt die auf den Sektor hochgerechneten Ergebnisse im Branchenvergleich und detailliert fuer die einzelnen Untersuchungsbereiche dar, z.B. fuer Kfz-Gewerbe, Baeckereien, Landwirtschaft, Einzelhandel, Hotels, Oeffentliche Verwaltungen. Daten zu

  7. What affects the innovation performance of small and medium-sized enterprises (SMEs) in the biotechnology industry? An empirical study on Korean biotech SMEs.

    Science.gov (United States)

    Kang, Kyung-Nam; Lee, Yoon-Sik

    2008-10-01

    Research-intensive small and medium-sized enterprises (SMEs) play a crucial role in the advancement of the biotechnology industry. This paper explored the impacts of internal and contextual variables on innovative activity in Korea and compared the results of this analysis with previous studies of other countries. Our analysis of 149 Korean biotech SMEs showed that the ratio of R&D expenditure to sales, the ratio of R&D employees to total employees, CEO characteristics, governmental support and international networking are positively correlated with a firm's innovation performance. The results may help decision makers to better foster SMEs in the Korean biotechnology industry.

  8. MEDIATEURS effects innovative behavior of the owner-manager on the relationship between human capital and the success of small and medium-sized enterprises in Tunisia

    OpenAIRE

    Samout, Ammar; BOUDABOUS, Sami

    2016-01-01

    International audience; The studies on the innovative behavior of the owner-manager in the context of Tunisia have not been the subject of a great interest in our environment. We are interested in the influence of human capital on the success of small and medium sized Tunisian businesses through the mediation of the innovative behavior of the owner-manager. To answer the above question, of descriptive analysis and econometric techniques have been conducted on a sample of 275 owners-leader of ...

  9. Benefits and challenges of using social media in marketing strategy:investigating small- and medium-sized companies in the Oulu region

    OpenAIRE

    Orajärvi, P. (Paavo)

    2016-01-01

    This thesis explains what social media marketing is as a phenomenon and what kind of roles it can fill in a company’s overall marketing strategies. The thesis also provides very practical information on how small/medium-sized companies can use social media channels in their daily marketing activities. This has been achieved through a literature review on the topic supported by an empirical multi-case study. The motivation for doing qualitative research of social media marketing in small/mediu...

  10. Computational molecular technology towards macroscopic chemical phenomena-molecular control of complex chemical reactions, stereospecificity and aggregate structures

    Energy Technology Data Exchange (ETDEWEB)

    Nagaoka, Masataka [Graduate School of Information Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Honmachi, Kawaguchi 332-0012 (Japan); ESICB, Kyoto University, Kyodai Katsura, Nishikyo-ku, Kyoto 615-8520 (Japan)

    2015-12-31

    A new efficient hybrid Monte Carlo (MC)/molecular dynamics (MD) reaction method with a rare event-driving mechanism is introduced as a practical ‘atomistic’ molecular simulation of large-scale chemically reactive systems. Starting its demonstrative application to the racemization reaction of (R)-2-chlorobutane in N,N-dimethylformamide solution, several other applications are shown from the practical viewpoint of molecular controlling of complex chemical reactions, stereochemistry and aggregate structures. Finally, I would like to mention the future applications of the hybrid MC/MD reaction method.

  11. Uncovering Oscillations, Complexity, and Chaos in Chemical Kinetics Using Mathematica

    Science.gov (United States)

    Ferreira, M. M. C.; Ferreira, W. C., Jr.; Lino, A. C. S.; Porto, M. E. G.

    1999-06-01

    Unlike reactions with no peculiar temporal behavior, in oscillatory reactions concentrations can rise and fall spontaneously in a cyclic or disorganized fashion. In this article, the software Mathematica is used for a theoretical study of kinetic mechanisms of oscillating and chaotic reactions. A first simple example is introduced through a three-step reaction, called the Lotka model, which exhibits a temporal behavior characterized by damped oscillations. The phase plane method of dynamic systems theory is introduced for a geometric interpretation of the reaction kinetics without solving the differential rate equations. The equations are later numerically solved using the built-in routine NDSolve and the results are plotted. The next example, still with a very simple mechanism, is the Lotka-Volterra model reaction, which oscillates indefinitely. The kinetic process and rate equations are also represented by a three-step reaction mechanism. The most important difference between this and the former reaction is that the undamped oscillation has two autocatalytic steps instead of one. The periods of oscillations are obtained by using the discrete Fourier transform (DFT)-a well-known tool in spectroscopy, although not so common in this context. In the last section, it is shown how a simple model of biochemical interactions can be useful to understand the complex behavior of important biological systems. The model consists of two allosteric enzymes coupled in series and activated by its own products. This reaction scheme is important for explaining many metabolic mechanisms, such as the glycolytic oscillations in muscles, yeast glycolysis, and the periodic synthesis of cyclic AMP. A few of many possible dynamic behaviors are exemplified through a prototype glycolytic enzymatic reaction proposed by Decroly and Goldbeter. By simply modifying the initial concentrations, limit cycles, chaos, and birhythmicity are computationally obtained and visualized.

  12. Characterization of the origin of fine particulate matter in a medium size urban area in the Mediterranean

    Science.gov (United States)

    Pikridas, Michael; Tasoglou, Antonios; Florou, Kalliopi; Pandis, Spyros N.

    2013-12-01

    A multi-stage methodology for investigating particulate pollution is developed and implemented for the case study area of Patras, Greece. Initially a low cost particulate matter mass monitor was used to assess aerosol mass concentrations indicating that the city, despite its small size (population around 200,000) and lack of heavy industry, violates both the daily and annual European Union PM standards. Increased PM10 concentrations were observed during the winter but local vehicular traffic was estimated to account for only 12 ± 4% of the PM10 concentration on an annual basis. In the second stage, PM2.5 chemical composition was measured at the urban center and biomass burning was identified as a major PM source during the colder months. In the third stage, PM2.5 concentration and chemical composition was also followed at a mostly upwind rural site around 40 km from the city. The transported pollution was found to account for 50% of the PM2.5 during winter and for more than 70% during the rest of the year. Almost all of the sulfates and 40-90%, depending on the season, of the organic aerosol are transported to the city from other areas. In the last stage, an intensive campaign took place during winter in order to quantify PM sources during the most polluted period. Nighttime sharp increases of the aerosol levels were observed with organic aerosol levels exceeding 80 μg m-3. Local biomass combustion and fossil fuel emissions for domestic heating were responsible for these levels.

  13. The impact of transformational CEOs on the performance of small- to medium-sized firms: does organizational context matter?

    Science.gov (United States)

    Ling, Yan; Simsek, Zeki; Lubatkin, Michael H; Veiga, John F

    2008-07-01

    Although theory suggests that CEOs who engage in transformational leadership should have a positive effect on firm performance, most empirical examinations using data drawn from larger firms have failed to find support for this linkage. Given that the organizational complexity associated with larger firms has been viewed as a central obstacle to establishing this important link, the authors examined the impact of CEO transformational leadership on firm performance in smaller, privately held firms. After first explaining why the less complex context of these firms provides a setting for transformational CEOs to play a more direct role in enhancing firm performance, they then further clarified the nature of this link by hypothesizing 3 contingencies that they argued are particularly salient: firm size, CEO founder status (founder or nonfounder), and CEO tenure. Results from a multisource survey of CEOs and their top management teams in 121 firms and 2 time-lagged measures of performance, 1 objective and 1 perceived, provided consistent support for these hypotheses.

  14. Genetic and chemical diversity of high mucilaginous plants of Sida complex by ISSR markers and chemical fingerprinting.

    Science.gov (United States)

    Thul, Sanjog T; Srivastava, Ankit K; Singh, Subhash C; Shanker, Karuna

    2011-09-01

    A method was developed based on multiple approaches wherein DNA and chemical analysis was carried out toward differentiation of important species of Sida complex that is being used for commercial preparation. Isolated DNA samples were successfully performed through PCR amplification using ISSR markers and degree of genetic diversity among the different species of Sida is compared with that of chemical diversity. For genetic fingerprint investigation, selected 10 ISSR primers generating reproducible banding patterns were used. Among the total of 63 amplicons, 62 were recorded as polymorphic, genetic similarity index deduced from ISSR profiles ranged from 12 to 51%. Based on similarity index, S. acuta and S. rhombifolia found to be most similar (51%). High number of species-specific bands played pivotal role to delineate species at genetic level. Investigation based on HPTLC fingerprints analysis revealed 23 bands representing to characteristic chemicals and similarity index ranged from 73 to 91%. Prominent distinguishable bands were observed only in S. acuta, while S. cordifolia and S. rhombifolia shared most bands making them difficult to identify on chemical fingerprint basis. This report summarizes the genotypic and chemotypic diversity and the use of profiles for authentication of species of Sida complex.

  15. Using MUSIC and CC(CONH for Backbone Assignment of Two Medium-Sized Proteins Not Fully Accessible to Standard 3D NMR

    Directory of Open Access Journals (Sweden)

    Annette K. Brenner

    2014-06-01

    Full Text Available The backbone assignment of medium-sized proteins is rarely as straightforward as that of small proteins, and thus often requires creative solutions. Here, we describe the application of a combination of standard 3D heteronuclear methods with CC(CONH and a variety of MUltiplicity Selective In-phase Coherence transfer (MUSIC experiments. Both CC(CONH and MUSIC are, in theory, very powerful methods for the backbone assignment of proteins. Due to low sensitivity, their use has usually been linked to small proteins only. However, we found that combining CC(CONH and MUSIC experiments simplified the assignment of two challenging medium-sized proteins of 13 and 19.5 kDa, respectively. These methods are to some extent complementary to each other: CC(CONH acquired with a long isotropic mixing time can identify amino acids with large aliphatic side chains. Whereas the most sensitive MUSIC experiments identify amino acid types that cannot be detected by CC(CONH, comprising the residues with acid and amide groups, and aromatic rings in their side chains. Together these methods provide a means of identifying the majority of peaks in the 2D 15N HSQC spectrum which simplifies the backbone assignment work even for proteins, e.g., small kinases, whose standard spectra resulted in little spectral resolution and low signal intensities.

  16. Using MUSIC and CC(CO)NH for backbone assignment of two medium-sized proteins not fully accessible to standard 3D NMR.

    Science.gov (United States)

    Brenner, Annette K; Frøystein, Nils Åge

    2014-06-26

    The backbone assignment of medium-sized proteins is rarely as straightforward as that of small proteins, and thus often requires creative solutions. Here, we describe the application of a combination of standard 3D heteronuclear methods with CC(CO)NH and a variety of MUltiplicity Selective In-phase Coherence transfer (MUSIC) experiments. Both CC(CO)NH and MUSIC are, in theory, very powerful methods for the backbone assignment of proteins. Due to low sensitivity, their use has usually been linked to small proteins only. However, we found that combining CC(CO)NH and MUSIC experiments simplified the assignment of two challenging medium-sized proteins of 13 and 19.5 kDa, respectively. These methods are to some extent complementary to each other: CC(CO)NH acquired with a long isotropic mixing time can identify amino acids with large aliphatic side chains. Whereas the most sensitive MUSIC experiments identify amino acid types that cannot be detected by CC(CO)NH, comprising the residues with acid and amide groups, and aromatic rings in their side chains. Together these methods provide a means of identifying the majority of peaks in the 2D 15N HSQC spectrum which simplifies the backbone assignment work even for proteins, e.g., small kinases, whose standard spectra resulted in little spectral resolution and low signal intensities.

  17. An Assessment of the Influence of Selected on the Performance of Small to Medium Sized Family Owned Businesses in the Zimbabwe Retail Sector

    Directory of Open Access Journals (Sweden)

    Maxwell Sandada

    2015-10-01

    Full Text Available The study attempted to assess the factors that are affecting business performance of small to medium sized family owned businesses in the Zimbabwean retail sector. The objective was to establish the effect of innovation, management skills, succession planning and corporate governance on family owned SMEs in Zimbabwe. The study sought to complement other previous studies that were carried out in other different contexts by producing evidence on the same phenomenon from a developing country context. The study adopted a quantitative approach. A self-administered survey was conducted to collect data that was analysed using descriptive, correlation and regression analyses. The results showed that the most significant factors affecting business performance in order of predictive power were innovation, proper management skills, succession planning and corporate governance. The findings have implications to family business managers and owners in Zimbabwe who are encouraged to be innovative, properly manage, practise succession planning and be guided by business morals in managing their enterprises. Whilst the factors ensuring the success of Small and Medium sized enterprises have extensively been examined, there is dearth of research on family business success factors especially in a developing country like Zimbabwe.

  18. Linking human capital and enterprise sustainability in Indonesian medium-sized food manufacturing enterprises: the role of informal knowledge sharing practice

    Science.gov (United States)

    Sunardi, O.

    2017-12-01

    Medium-sized food manufacturing enterprises in Indonesia are significant in a number of contexts, in terms of their part to the national production (GDP) and their establishment to the employment. In term of their role to national production, manufacturing sector contributes the highest GDP by 85%. In this sector, food manufacturing subsector contributes the highest GDP. Nevertheless, they faced the same common problems: quality of human capital and sustainability issues. Previous government supplementary programs have been established to expand the human capital capability amongst medium enterprises. Adequate amount of fund has been apportioned to develop human capital, though, the medium enterprises sustainability is still in question. This study proposes and examines the human capital role from informal knowledge sharing perspective. By conducting qualitative approach through interviews to four informants in Indonesian medium-sized food manufacturing enterprises, a set of hypotheses is derived from this study for future quantitative study. This study indicates that human capital traits (diverse education background, employee skills, and employee experience) could leverage the practice of informal knowledge sharing. Constructs such as mutual trust and reciprocal intention could play as mediating variables, and cultural interpretation perspective could act as moderating factor to informal knowledge sharing effectiveness. In final, informal knowledge sharing is indicated to play as moderating variable for human capital policy and practice to support enterprise sustainability.

  19. Vaccine Pipeline Has Grown During The Past Two Decades With More Early-Stage Trials From Small And Medium-Size Companies.

    Science.gov (United States)

    Hwang, Thomas J; Kesselheim, Aaron S

    2016-02-01

    Many serious diseases lack safe and effective vaccines. Using a large commercial database, we examined trends in global vaccine research and development and found that the proportion of new vaccine candidates entering all stages of clinical development increased by 3-5 percentage points over the past two decades. Small and medium-size companies accounted for nearly twice as many new Phase I vaccine trials compared to large companies, but late-stage (Phase III) vaccine trials were dominated by large companies. There were no significant differences between vaccines and drugs in the probability of success in clinical trials or in profitability. Small and medium-size companies, including spin-outs from academic research centers, play an important role in innovative research and discovery. Our findings suggest that policy making targeted at smaller companies, such as prizes or opportunities for public-private partnerships, could support the development of new vaccines, particularly those targeting unmet medical needs and emerging public health threats. Project HOPE—The People-to-People Health Foundation, Inc.

  20. Purification of molybdenum oxide, growth and characterization of medium size zinc molybdate crystals for the LUMINEU program

    Directory of Open Access Journals (Sweden)

    Shlegel V.N.

    2014-01-01

    Full Text Available The LUMINEU program aims at performing a pilot experiment on neutrinoless double beta decay of 100Mo using radiopure ZnMoO4 crystals operated as scintillating bolometers. Growth of high quality radiopure crystals is a complex task, since there are no commercially available molybdenum compounds with the required levels of purity and radioactive contamination. This paper discusses approaches to purify molybdenum and synthesize compound for high quality radiopure ZnMoO4 crystal growth. A combination of a double sublimation (with addition of zinc molybdate with subsequent recrystallization in aqueous solutions (using zinc molybdate as a collector was used. Zinc molybdate crystals up to 1.5 kg were grown by the low-thermal-gradient Czochralski technique, their optical, luminescent, diamagnetic, thermal and bolometric properties were tested.

  1. Complex chemical burns following a mass casualty chemical plant incident: how optimal planning and organisation can make a difference.

    Science.gov (United States)

    O'Neill, Tomás B; Rawlins, Jeremy; Rea, Suzanne; Wood, Fiona

    2012-08-01

    Four employees at a chemical plant sustained extensive chemical burns following the explosion of a pipeline containing 100% sulphuric acid. We describe the management of these patients from the initial ED triage through to discharge from hospital in life and limb threatening chemical burns. Four patients who sustained chemical burns to the torso and extremities are reviewed. Data was retrieved from patient case notes and operating theatre logbooks. Four patients sustained chemical burns during the blast and were immediately transferred to a local ED where a prompt referral was made to the burns service. All patients were male aged 25-59 years (mean 46.5). Burn size was 2-50% BSA (mean 22.5). Following RFDS transfer to the state burns service two patients required immediate excisional surgery. In these patients the chemical burn involved full thickness skin loss with extensive underlying muscle and neurovascular damage. One patient required immediate above knee amputation of one leg and fascial burn excision of the other. The other patient required fascial burn excision of both legs followed by Integra placement 24h later. Both patients had prolonged hospital stays due to the complex nature of their injuries requiring multiple trips to theatre and lengthy rehabilitation. The two patients with smaller burns had straightforward surgery and an unremarkable recovery. Early communication following this mass casualty incident allowed for organisation of tertiary services and early radical surgery which was life saving. Management lessons were learnt following this mass casualty chemical burn incident. Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.

  2. Occurrence of large and medium-sized mammals: Occurrence but not count models predict pronghorn distribution: Chapter 8

    Science.gov (United States)

    2011-01-01

    Management of medium to large-sized terrestrial mammals (Antilocapridae, Canidae, Cervidae, Leporidae, Mustelidae, Ochotonidae) in the western United States is multifaceted and complex. Species in this group generally are charismatic and provide economic opportunities, although others are considered a nuisance at one extreme or are listed as species of conservation concern at the other. Understanding the relative influence of land cover, habitat fragmentation, and human land use on their distribution during the breeding season is imperative to inform management decisions on land use and conservation planning for these species. We surveyed medium to large-sized sagebrush (Artemisia spp.)-associated mammal species in 2005 and 2006 on 141 random transects (mean length = 1.1 km) in the Wyoming Basins, an area undergoing rapid land cover transformation due to human actions including energy development. Overall, we observed 10 species but only obtained enough observations of pronghorn (Antilocapra americana) to develop spatially explicit distribution models. For pronghorn, occurrence related positively to proportion of sagebrush land cover within 0.27 km, mixed shrubland land cover within 3 km, riparian land cover within 5 km, Normalized Difference Vegetation Index (NDVI) within 0.27 km, road density within 5 km, and decay distance to power line corridors at 1 km, but negatively to salt-desert shrubland cover within 18 km and an interaction between sagebrush and NDVI within 0.27 km. We found excellent predictive capability of this model when evaluated with independent test data. The model provides a basis for assessing the effects of proposed development on pronghorn and can aid planning efforts to avoid or mitigate adverse effects on pronghorn.

  3. First-visit patients without a referral to the Department of Internal Medicine at a medium-sized acute care hospital in Japan: an observational study

    Directory of Open Access Journals (Sweden)

    Kajiwara N

    2017-10-01

    Full Text Available Nobuyuki Kajiwara,1 Kazuyuki Hayashi,1 Masahiro Misago,2 Shinichiro Murakami,2 Takato Ueoka2 1Department of Nephrology, Ikeda City Hospital, 2Department of General Medicine, Ikeda City Hospital, Johnan, Osaka, Japan Purpose: We sought to profile first-time patients without a referral who sought medical care at the Department of Internal Medicine at a medium-sized acute care hospital in Japan. We anticipated that the analysis would highlight the demand for medical care needs from acute care hospitals and help confirm one of the problems associated with primary care in Japan. Patients and methods: The study population comprised 765 patients who sought outpatient consultation without a referral at “the Department of General Internal Medicine” at the Ikeda City Hospital on Fridays over 4 years. Data on the following variables were collected: age, sex, examination date, reason for encounter (RFE, diagnosis, as well as history of consultation with or without antibiotic treatment at another medical institution for the same RFE. We used the International Classicication of Primary Care, Revised Second edition (ICPC-2-R codes for RFEs and diagnoses. Results: The main RFE fields were digestive (ICPC-2-R Chapter D, general and unspecified (A, and respiratory (R. The main diagnosis fields were digestive (D, respiratory (R, general and unspecified (A, and musculoskeletal (L. In total, 27.6% of patients had sought consultation at another medical institution for the same RFE. Of these, 64.7% of patients for whom the RFE was cough (ICPC-2-R code, R05, and 72.0% for whom the RFE was fever (A03 were prescribed antibiotics. In total, 62.4% of patients underwent emergency investigations and waited for the results; 4.3% were hospitalized on the same day; and 60.5% were medicated at the initial examination. In 11.5%, the main underlying problem appeared to be psychosomatic. Conclusion: We used the ICPC-2-R to analyze the state of first-visit patients without a

  4. Mapping of Drug-like Chemical Universe with Reduced Complexity Molecular Frameworks.

    Science.gov (United States)

    Kontijevskis, Aleksejs

    2017-04-24

    The emergence of the DNA-encoded chemical libraries (DEL) field in the past decade has attracted the attention of the pharmaceutical industry as a powerful mechanism for the discovery of novel drug-like hits for various biological targets. Nuevolution Chemetics technology enables DNA-encoded synthesis of billions of chemically diverse drug-like small molecule compounds, and the efficient screening and optimization of these, facilitating effective identification of drug candidates at an unprecedented speed and scale. Although many approaches have been developed by the cheminformatics community for the analysis and visualization of drug-like chemical space, most of them are restricted to the analysis of a maximum of a few millions of compounds and cannot handle collections of 108-1012 compounds typical for DELs. To address this big chemical data challenge, we developed the Reduced Complexity Molecular Frameworks (RCMF) methodology as an abstract and very general way of representing chemical structures. By further introducing RCMF descriptors, we constructed a global framework map of drug-like chemical space and demonstrated how chemical space occupied by multi-million-member drug-like Chemetics DNA-encoded libraries and virtual combinatorial libraries with >1012 members could be analyzed and mapped without a need for library enumeration. We further validate the approach by performing RCMF-based searches in a drug-like chemical universe and mapping Chemetics library selection outputs for LSD1 targets on a global framework chemical space map.

  5. Prototyping of chemical composition of complex crystals using method of neural networks

    Science.gov (United States)

    Blagin, A. V.; Nefedov, V. V.; Nefedova, N. A.

    2017-10-01

    The traditional methods of study of multi-component crystal heterojunction structures by means of X-ray diffractometry and electroscopy are expensive and complex. The present paper discusses the information technology based on the use of artificial neural networks for identification of the chemical composition of complex semiconductor structures. The obtained results allow supposing the successful use of this method for many multi-component systems.

  6. Aspects Regarding the Development and the Integration of the Corporate Social Responsibility Concept in Firms’ Behaviour. Particularities for Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Georgeta Vintila

    2009-07-01

    Full Text Available Starting from the concept of Corporate Social Responsibility (CSR, the purpose of this article is to highlight some of the particularities, at Small and Medium-sized Enterprises (SMEs level, regarding: socially responsible behaviour and participation in actions related to CSR; type of CSR strategies adopted by SMEs as compared to larger firms; the motivations, benefits and constraints of the social involvement. The ultimate question refers to the existence, nature and implications of a link between the firm size and the aspects mentioned above. These aspects will be presented according to the conclusions of the previous studies conducted in this area of research, the present paper representing therefore a theoretical synthesis of the existant literature.

  7. E-poslovanje v slovenskih malih in srednje velikih podjetjih = E-business in Slovenian Small and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Viktorija Sulcic

    2008-12-01

    Full Text Available In the paper the position of Slovenian small and medium-sized enterprises in the field of e-business is presented. In the first part of the paper we compare the prevalence of e-business practices in Slovenia and EU countries and present the intensity of Slovene SME’s use of ebusiness as well. The second part of the paper is based on a research conducted with a sample of 49 Slovenian small and mediumsized enterprises. By performing a data analysis, we show the prevalence of SME’s individual internet activities and compare them with the research data collected by the national statistical office a year and a half ago. The e-business impacts and the obstacles for e-business implementation are the most interesting part of the presented research.

  8. A perspective on open innovation in small- and medium-sized enterprises in South Africa, and design requirements for an open innovation approach

    Directory of Open Access Journals (Sweden)

    Krause, Willie

    2015-05-01

    Full Text Available This paper provides key results from an exploratory research study aimed at understanding the current landscape in small- and medium-sized enterprises (SMEs in South Africa with regard to their appetite for, and use of, open innovation. The survey, which was conducted within a contained group of SMEs that belong to business network groups on LinkedIn, explored the current use and perception of open innovation. It was found that collaboration is the approach most preferred by the SMEs surveyed, with customers and suppliers as their preferred innovation partners. Based on the findings of the survey, this paper proposes 25 design requirements, grouped into five functional categories, for an open innovation approach. The design requirements have been developed as a primer to a more complete open innovation approach for SMEs.

  9. SURVEY ON THE EMPLOYEES’ FITNESS CONDITION AND THE EMPLOYERS’ HEALTH PRESERVATION POSSIBILITIES IN CASE OF SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Tamás MADARÁSZ

    2016-07-01

    Full Text Available Consideration of the employees’ health preservation results in direct cost savings at corporate level by decreasing the measure of sick leave and ensuring the continuous and smooth production. Nowadays, ensuring the health of labour force has already become an employer interest, of course, in addition to that it is also the interest of everyone. In our research, we have asked employees of Hungarian small and medium-sized enterprises in the framework of questionnaire survey. It was clearly apparent that the physical activity of workers has to be enhanced and their sporting activities have to be supported. According to the results of our research, these types of organizations support the health protection of their employees, moreover in financing form of allowances primarily.

  10. The analysis of the business registration reform and the situation of small and medium sized enterprises in the Republic of Srpska

    Directory of Open Access Journals (Sweden)

    Dušanić-Gačić Svetlana

    2016-01-01

    Full Text Available The largest number of companies in the Republic of Srpska falls into the category of small and medium-sized enterprises (SMEs and most of them are organized in the form of limited liability companies, usually with the prescribed minimum share capital. The economic sector and its actors still face many difficulties and obstacles in their functioning. Unfavourable business environment is characterized by high operating costs caused by high taxes and contributions, a number of fiscal and parafiscal charges, various fees, bureaucracy, unfavorable loans, debt collection dispute, smuggling, illegal work, corruption... The aim of this paper is to analyze the effects of the reforms made in the field of business registration, such as the introduction of one-stop business registration system and the exemption from judicial and administrative fees during the first registration, as well as their impact on improving the overall business environment in the Republic of Srpska.

  11. Organizational-level interventions in small and medium-sized enterprises: Enabling and inhibiting factors in the PoWRS program

    DEFF Research Database (Denmark)

    Ipsen, Christine; Gish, Liv; Poulsen, Signe

    2015-01-01

    Work-related stress in small and medium-sized enterprises (SMEs) is an increasing problem. However, knowledge regarding organizational-level interventions in SMEs is limited, and SMEs often lack professional facilitator resources to assist in change processes. An intervention program developed...... for large corporations, the PoWRS (Prevention of Work-Related Stress) program, has been modified to fit the conditions in SMEs, i.e., appointing employees as in-house facilitators. The aim of this paper is to examine the enablers and inhibiting factors of the PoWRS program when applied in four Danish SMEs....... Three out of four of the case companies succeeded in implementing the program. The enablers and inhibiting factors related to three themes: persons and roles, program components, and organizational context. Findings show that the primary enabling factors were the in-house employee facilitators...

  12. Impact of Platelet-Rich Plasma on Arthroscopic Repair of Small- to Medium-Sized Rotator Cuff Tears: A Randomized Controlled Trial.

    Science.gov (United States)

    Holtby, Richard; Christakis, Monique; Maman, Eran; MacDermid, Joy C; Dwyer, Tim; Athwal, George S; Faber, Kenneth; Theodoropoulos, John; Woodhouse, Linda J; Razmjou, Helen

    2016-09-01

    Increased interest in using platelet-rich plasma (PRP) as an augment to rotator cuff repair warrants further investigation, particularly in smaller rotator cuff tears. To examine the effectiveness of PRP application in improving perioperative pain and function and promoting healing at 6 months after arthroscopic repair of small- or medium-sized rotator cuff tears. Randomized controlled trial; Level of evidence, 1. This was a double-blinded randomized controlled trial of patients undergoing arthroscopic repair of partial- or full-thickness rotator cuff tears of up to 3 cm who were observed for 6 months. Patients were randomized to either repair and PRP application (study group) or repair only (control group) groups. The patient-oriented outcome measures utilized were the visual analog scale (VAS), the Short Western Ontario Rotator Cuff Index (ShortWORC), the American Shoulder and Elbow Surgeons (ASES) form, and the Constant-Murley Score (CMS). Range of motion (ROM) and inflammatory and coagulation markers were measured before and after surgery. Magnetic resonance imaging was used at 6 months to assess retear and fatty infiltration rate. Eighty-two patients (41 males) with a mean age of 59 ± 8 years were enrolled; 41 patients were included in each group. Both the PRP and control groups showed a significant improvement in their pain level based on the VAS within the first 30 days (P .05), retear (14% vs 18% full retear; P = .44), or fatty infiltration rate (P = .08). The PRP biological augmentation for repair of small- to medium-sized rotator cuff tears has a short-term effect on perioperative pain without any significant impact on patient-oriented outcome measures or structural integrity of the repair compared with control group.

  13. First-visit patients without a referral to the Department of Internal Medicine at a medium-sized acute care hospital in Japan: an observational study.

    Science.gov (United States)

    Kajiwara, Nobuyuki; Hayashi, Kazuyuki; Misago, Masahiro; Murakami, Shinichiro; Ueoka, Takato

    2017-01-01

    We sought to profile first-time patients without a referral who sought medical care at the Department of Internal Medicine at a medium-sized acute care hospital in Japan. We anticipated that the analysis would highlight the demand for medical care needs from acute care hospitals and help confirm one of the problems associated with primary care in Japan. The study population comprised 765 patients who sought outpatient consultation without a referral at "the Department of General Internal Medicine" at the Ikeda City Hospital on Fridays over 4 years. Data on the following variables were collected: age, sex, examination date, reason for encounter (RFE), diagnosis, as well as history of consultation with or without antibiotic treatment at another medical institution for the same RFE. We used the International Classicication of Primary Care, Revised Second edition (ICPC-2-R) codes for RFEs and diagnoses. The main RFE fields were digestive (ICPC-2-R Chapter D), general and unspecified (A), and respiratory (R). The main diagnosis fields were digestive (D), respiratory (R), general and unspecified (A), and musculoskeletal (L). In total, 27.6% of patients had sought consultation at another medical institution for the same RFE. Of these, 64.7% of patients for whom the RFE was cough (ICPC-2-R code, R05), and 72.0% for whom the RFE was fever (A03) were prescribed antibiotics. In total, 62.4% of patients underwent emergency investigations and waited for the results; 4.3% were hospitalized on the same day; and 60.5% were medicated at the initial examination. In 11.5%, the main underlying problem appeared to be psychosomatic. We used the ICPC-2-R to analyze the state of first-visit patients without a referral visiting the Department of Internal Medicine at a medium-sized acute care hospital in Japan. Common RFEs were abdominal pain, cough, and fever. A tendency toward overprescription of antibiotics was observed among primary care physicians.

  14. The value of delaying hCG administration to enable maturation of medium-sized follicles in patients undergoing superovulation for IVF/ICSI.

    Science.gov (United States)

    Awonuga, Awoniyi O; Wheeler, Karen; Thakur, Mili; Jeelani, Roohi; Diamond, Michael P; Puscheck, Elizabeth E

    2017-09-30

    The purpose of the study is to determine whether continued stimulation of mature follicles to allow "catch up" growth of medium-sized follicles in assisted reproductive technology compromises the clinical pregnancy (CPR) and live birth (LBR) rates in IVF/ICSI cycles. This retrospective cohort study reviewed 200 first IVF ± ICSI cycles out of a total of 340 cycles with complete data. Women underwent stimulation protocols with gonadotropins (Gn) and GnRH antagonist. Treatment cycles were divided into two groups (Gp): hCG administration delayed despite the presence of two mature follicles, defined as ≥ 18 mm [Gp1, n = 79] and hCG administration given when there were two mature follicles [Gp2, n = 121]. The patients in Gp1 were significantly younger than those in Gp2 [32.9 (4.5) vs. 34.3 (4.8), p = 0.04] and needed a median of one more day of superovulation before ovulation was triggered with hCG. The extra days was associated with the use of 450 [75-2025] more Gn, such that at the time the hCG was administered, patient's in group 1 had developed significantly greater number of follicles ≥ 18 mm [mean (SD), 4.9 (1.8) vs. 3.4 (1.7), p hCG administration to allow further growth of the medium-sized follicles added further days of superovulation and cost without improvement in CPR and LBR.

  15. Monitoring the aeration efficiency and carbon footprint of a medium-sized WWTP: experimental results on oxidation tank and aerobic digester.

    Science.gov (United States)

    Caivano, Marianna; Bellandi, Giacomo; Mancini, Ignazio M; Masi, Salvatore; Brienza, Rosanna; Panariello, Simona; Gori, Riccardo; Caniani, Donatella

    2017-03-01

    The efficiency of aeration systems should be monitored to guarantee suitable biological processes. Among the available tools for evaluating the aeration efficiency, the off-gas method is one of the most useful. Increasing interest towards reducing greenhouse gas (GHG) emissions from biological processes has resulted in researchers using this method to quantify N2O and CO2 concentrations in the off-gas. Experimental measurements of direct GHG emissions from aerobic digesters (AeDs) are not available in literature yet. In this study, the floating hood technique was used for the first time to monitor AeDs. The floating hood technique was used to evaluate oxygen transfer rates in an activated sludge (AS) tank of a medium-sized municipal wastewater treatment plant located in Italy. Very low values of oxygen transfer efficiency were found, confirming that small-to-medium-sized plants are often scarcely monitored and wrongly managed. Average CO2 and N2O emissions from the AS tank were 0.14 kgCO2/kgbCOD and 0.007 kgCO2,eq/kgbCOD, respectively. For an AeD, 3 × 10-10 kgCO2/kgbCOD direct CO2 emissions were measured, while CO2,eq emissions from N2O were 4 × 10-9 kgCO2,eq/kgbCOD. The results for the AS tank and the AeD were used to estimate the net carbon and energy footprint of the entire plant.

  16. The impact of work experience of small and medium-sized enterprises owners or managers on their competitive intelligence awareness and practices

    Directory of Open Access Journals (Sweden)

    Rene Pellissier

    2013-02-01

    Full Text Available Background: Information technology has assisted in globalisation, which then assisted in making international trade easier. Consequently, businesses no longer compete with local competitors only but also with international ones, leading to intense competition in all business sectors. Businesses will hardly practice what they are not aware of and therefore needs to know about their competitive landscape. Competitive intelligence (CI gathers information from both the internal and external business environments, and analyses these for use by decision makers. Whilst awareness of the importance of CI is wide, it is not practiced optimally, making the need for creating awareness of the benefits of CI important.Objectives: The objective of this research was to establish the influence of owners’ and managers' working experience of CI practice and awareness in the small and medium-sized enterprises (SMEs environment.Method: This research was quantitative in nature and a questionnaire was used to collect data from SMEs owners and managers in The City of Tshwane Metropolitan Municipality.Results: This research indicates that SMEs in the study are aware of CI through education and training. Moreover, the study reveals that the working experience of owners and managers has a great influence on awareness and practice of CI and one should implement training programmes in this domain to assist with building competitive advantage.Conclusion: Small and medium-sized enterprises owners or managers’ years of working experience has a greater influence on awareness and practice of CI. Put differently, years of working experience is a great predictor of CI awareness and practice.

  17. Ephemeral collision complexes mediate chemically termolecular transformations that affect system chemistry

    Science.gov (United States)

    Burke, Michael P.; Klippenstein, Stephen J.

    2017-11-01

    Termolecular association reactions involve ephemeral collision complexes—formed from the collision of two molecules—that collide with a third and chemically inert 'bath gas' molecule that simply transfers energy to/from the complex. These collision complexes are generally not thought to react chemically on collision with a third molecule in the gas-phase systems of combustion and planetary atmospheres. Such 'chemically termolecular' reactions, in which all three molecules are involved in bond making and/or breaking, were hypothesized long ago in studies establishing radical chain branching mechanisms, but were later concluded to be unimportant. Here, with data from ab initio master equation and kinetic-transport simulations, we reveal that reactions of H + O2 collision complexes with other radicals constitute major kinetic pathways under common combustion situations. These reactions are also found to influence flame propagation speeds, a common measure of global reactivity. Analogous chemically termolecular reactions mediated by ephemeral collision complexes are probably of significance in various combustion and planetary environments.

  18. Chemical speciation of L-glutamine complexes with Co(II), Ni(II) and ...

    African Journals Online (AJOL)

    The impact of cationic micelles on the protonation equilibria of L-glutamine and chemical speciation of its complexes with Co(II), Ni(II) and Cu(II) have been studied by monitoring hydrogen ion concentration pH metrically at 303 K and at an ionic strength of 0.16 M. The protonation constants and binary stability constants ...

  19. Sorption of heavy metal ions on new metal-ligand complexes chemically derived from Lycopodium clavatum

    Energy Technology Data Exchange (ETDEWEB)

    Pehlivan, E.; Ersoz, M.; Yildiz, S. [Univ. of Selcuk, Konya (Turkey); Duncan, H.J. [Univ. of Glasgow, Scotland (United Kingdom)

    1994-08-01

    Sorption of heavy metal ions from aqueous solution has been investigated as a function of pH using a novel exchanger system whereby Lycopodium clavatum is functionalized with carboxylate and glyoxime metal-ligand complexes. The new ligand exchangers were prepared using a reaction of diaminosporopollenin with various metal-ligand complexes of glyoxime and monocarboxylic acid. The sorptive behavior of these metal-ligand exchangers and the possibilities to remove and to recover selectively heavy metal cations using these systems are discussed on the basis of their chemical natures and their complexing properties.

  20. Medium size polarised deuteron target

    Energy Technology Data Exchange (ETDEWEB)

    Kiselev, Yu.F.; Polyakov, V.V.; Kovalev, A.I.; Bunyatova, E.I.; Borisov, N.S.; Trautman, V.Yu.; Werner, K.; Kozlenko, N.G.

    1984-03-01

    A frozen polarised deuteron target based on ethanediol with a high percentage of deuterium is described. Analytical expressions for the NMR spectrum correction for non-linearity of the Q-meter are obtained and a method for the determination of the asymmetry is developed. Experimental results confirm the thermal mixing theory for deuteron and proton spin systems with a dipole-dipole reservoir of electron spins.

  1. New strategy for chemically attachment of Schiff base complexes on Multiwalled Carbon Nanotubes surfaces

    Directory of Open Access Journals (Sweden)

    Leila Moradi

    2014-06-01

    Full Text Available Chemically attachment of Schiff base complexes on multiwalled carbon nanotubes (MWCNTs surfaces through a convenient and simple method was studied. In the first step of this method, we present a new method for preparation of aminated MWCNTs in order to attachment of (new chlorinated salen Schiff bases. Amination of multiwalled carbon nanotubes performed under microwave (MW irradiation through a one pot two step reaction. The chemically attachment of salen Schiff bases on functionalized MWCNTs (salen@MWCNTs performed under a facile simple nucleophilic substitution reaction and complexation of attached salen Schiff bases (salen complex@MWCNTs in last step, have been occurred with reaction of transition metal salts and salen@MWCNTs. The obtained products were characterized in detail, using FTIR, XRD, UV-Vis absorption, SEM and EDX methods.

  2. Prebiotic coordination chemistry: The potential role of transition-metal complexes in the chemical evolution

    Science.gov (United States)

    Beck, M.

    1979-01-01

    In approaching the extremely involved and complex problem of the origin of life, consideration of the coordination chemistry appeared not only as a possibility but as a necessity. The first model experiments appear to be promising because of prebiotic-type synthesis by means of transition-metal complexes. It is especially significant that in some instances various types of vitally important substances (nucleic bases, amino acids) are formed simultaneously. There is ground to hope that systematic studies in this field will clarify the role of transition-metal complexes in the organizatorial phase of chemical evolution. It is obvious that researchers working in the fields of the chemistry of cyano and carbonyl complexes, and of the catalytic effect of transition-metal complexes are best suited to study these aspects of the attractive and interesting problem of the origin of life.

  3. Physico-Chemical and In-vitro Microbial Studies of Newly Synthesis Organometallic Complexes

    Directory of Open Access Journals (Sweden)

    Isam Hussain Al-Karkhi

    2014-05-01

    Full Text Available Drugs normally synthesized to use as medication to treat diseases like cancer and microbial infections, these synthesized drugs were interested more than naturally-derived drugs which have been shows low activity or not as efficient against diseases. A new ligand 3-methylbenzyl (2Z-2-[1-(pyridin-4-ylethylidene]hydrazine carbodithioate (PE3MBC and its Cd(II, Cu(II, Co(II and Zn(II metal complexes. The new ligand and metal complexes were characterized via various physico-chemical and spectroscopic techniques. Cd(II complex show more activity against microbes and against cancer cell line MCF-7, while other complexes does not shows activity like cadmium complex, all the complexes does not shows any activity against MDAMB-231 cell line. The fatal of the cancer and the microbes cell was due to inhibition of DNA synthesis which was probably due to chelating with metals complexes, or could be referred to lipophilicity, presence of hydrophobic moiety in the complex molecule, also could be due to steric effects and electronic effects.

  4. Mental health status and work environment among workers in small- and medium-sized enterprises in Guangdong, China-a cross-sectional survey.

    Science.gov (United States)

    Zeng, Zhi; Guo, Yan; Lu, Liming; Han, Lu; Chen, Wen; Ling, Li

    2014-11-12

    Small- and medium-sized enterprises (SMEs) generate nearly 80% of the jobs in China, but the dangerous work environment often found in these enterprises poses a major concern for public health. Psychosocial pressure and mental health problems among the workers are also common in SMEs. However, mental health of workers in SMEs is largely neglected in occupational health research and practice in China. The purpose of this study is to assess mental health of the workers and to explore the associations between physical and psychosocial work environment and workers' mental health in SMEs in South China. Data were collected in 2012 through a cross-sectional survey among 1200 workers working in small- and medium-sized enterprises (SMEs) in Guangdong, China. Mental health was measured by psychological well-being in the current study. Job Demand-Control-Support (JDCS) model was used as a theoretical framework to examine the psychosocial factors associated with workers' psychological well-being. Data were analyzed using SPSS 20.0 and analysis was performed using bivariate analyses and multivariate logistic regression. About three in ten workers (35.3%) in the sample had poor psychological well-being. Those who were men, younger in age, or migrant workers had worse psychological outcome in bivariate analyses. After controlling for individual variables (gender, age, marital status, and household registration), we found that longer weekly work hours (OR = 1.30, 95% CI: 1.13 ~ 1.50), more exposure to hazardous work environment (OR = 1.26, 95% CI: 1.10 ~ 1.44), higher job demands (OR = 1.29, 95% CI: 1.12 ~ 1.49), and lower job autonomy (OR = 0.70, 95% CI: 0.60 ~ 0.81) were significant associated with worse psychological well-being. The results were consistent with predictions of the JDCS model. The results indicate that the JDCS model is a useful framework in predicting psychological well-being among Chinese workers in SMEs. Future mental health promotion should focus on young

  5. Radiological and chemical source terms for Solid Waste Operations Complex. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Boothe, G.F.

    1994-06-03

    The purpose of this document is to describe the radiological and chemical source terms for the major projects of the Solid Waste Operations Complex (SWOC), including Project W-112, Project W-133 and Project W-100 (WRAP 2A). For purposes of this document, the term ``source term`` means the design basis inventory. All of the SWOC source terms involve the estimation of the radiological and chemical contents of various waste packages from different waste streams, and the inventories of these packages within facilities or within a scope of operations. The composition of some of the waste is not known precisely; consequently, conservative assumptions were made to ensure that the source term represents a bounding case (i.e., it is expected that the source term would not be exceeded). As better information is obtained on the radiological and chemical contents of waste packages and more accurate facility specific models are developed, this document should be revised as appropriate. Radiological source terms are needed to perform shielding and external dose calculations, to estimate routine airborne releases, to perform release calculations and dose estimates for safety documentation, to calculate the maximum possible fire loss and specific source terms for individual fire areas, etc. Chemical source terms (i.e., inventories of combustible, flammable, explosive or hazardous chemicals) are used to determine combustible loading, fire protection requirements, personnel exposures to hazardous chemicals from routine and accident conditions, and a wide variety of other safety and environmental requirements.

  6. Europium(III) Macrocyclic Complexes with Alcohol Pendant Groups as Chemical Exchange Saturation Transfer Agents

    Science.gov (United States)

    Woods, Mark; Woessner, Donald E.; Zhao, Piyu; Pasha, Azhar; Yang, Meng-Yin; Huang, Ching-Hui; Vasalitiy, Olga; Morrow, Janet R.; Sherry, A. Dean

    2009-01-01

    Paramagnetic lanthanide(III) complexes that contain hyperfine-shifted exchangeable protons offer considerable advantages over diamagnetic molecules as chemical exchange saturation transfer (CEST) agents for MRI. As part of a program to investigate avenues to improve the sensitivity of such agents, the CEST characteristics of europium(III) macrocyclic complexes having appended hydroxyethyl groups were investigated. The CEST spectrum of the asymmetrical complex, EuCNPHC3+, shows five distinct peaks for each magnetically nonequivalent exchangeable proton in the molecule. The CEST spectra of this complex were fitted to NMR Bloch theory to yield exchange rates between each of six exchanging proton pools (five on the agent plus bulk water). Exchange between the Eu3+-bound hydroxyl protons and bulk water protons was slow in dry acetonitrile but accelerated incrementally upon stepwise addition of water. In pure water, exchange was too fast to observe a CEST effect. The utility of this class of europium(III) complex for CEST imaging applications is ultimately limited by the small chemical shifts induced by the hydroxyl-appended ligands of this type and the resulting small Δω values for the exchangeable hydroxyl protons. PMID:16881645

  7. Modified CTAB and TRIzol protocols improve RNA extraction from chemically complex Embryophyta.

    Science.gov (United States)

    Jordon-Thaden, Ingrid E; Chanderbali, Andre S; Gitzendanner, Matthew A; Soltis, Douglas E

    2015-05-01

    Here we present a series of protocols for RNA extraction across a diverse array of plants; we focus on woody, aromatic, aquatic, and other chemically complex taxa. Ninety-one taxa were subjected to RNA extraction with three methods presented here: (1) TRIzol/TURBO DNA-free kits using the manufacturer's protocol with the addition of sarkosyl; (2) a combination method using cetyltrimethylammonium bromide (CTAB) and TRIzol/sarkosyl/TURBO DNA-free; and (3) a combination of CTAB and QIAGEN RNeasy Plant Mini Kit. Bench-ready protocols are given. After an iterative process of working with chemically complex taxa, we conclude that the use of TRIzol supplemented with sarkosyl and the TURBO DNA-free kit is an effective, efficient, and robust method for obtaining RNA from 100 mg of leaf tissue of land plant species (Embryophyta) examined. Our protocols can be used to provide RNA of suitable stability, quantity, and quality for transcriptome sequencing.

  8. Calculation of complex chemical equilibrium compositions of composite rocket propellants combustion products

    Directory of Open Access Journals (Sweden)

    NIKOLA KILIBARDA

    2000-11-01

    Full Text Available An adequate method for calculating chemical equilibrium in a predominantly gaseous, multi-component reactive mixture was investigated and successfully applied. This method involves the stated equilibrium reaction scheme, including, first, the formation of chemical species, of which concentrations prevail in the mixture, then the formation of gaseous atomic species by dissociation of previous ones, and, finally, the formation of complex chemical species from the atomic species. A computer program, which permits calculations of equilibrium compositions by the iteration procedure, has been developed. The results of calculations have been compared with data obtained by the programs OPHELIE, MICROPEP, and the program SPP, as documented in the NASA-Lewis Code, which is presently the world-wide standard. All comparisons gave satisfactory agreement.

  9. A large scale analysis of information-theoretic network complexity measures using chemical structures.

    Directory of Open Access Journals (Sweden)

    Matthias Dehmer

    Full Text Available This paper aims to investigate information-theoretic network complexity measures which have already been intensely used in mathematical- and medicinal chemistry including drug design. Numerous such measures have been developed so far but many of them lack a meaningful interpretation, e.g., we want to examine which kind of structural information they detect. Therefore, our main contribution is to shed light on the relatedness between some selected information measures for graphs by performing a large scale analysis using chemical networks. Starting from several sets containing real and synthetic chemical structures represented by graphs, we study the relatedness between a classical (partition-based complexity measure called the topological information content of a graph and some others inferred by a different paradigm leading to partition-independent measures. Moreover, we evaluate the uniqueness of network complexity measures numerically. Generally, a high uniqueness is an important and desirable property when designing novel topological descriptors having the potential to be applied to large chemical databases.

  10. [Study on actual situation of community industrial physicians for small and medium-sized enterprises and their involvement in community occupational health services].

    Science.gov (United States)

    Terada, Hayato; Sone, Tomofumi; Takemura, Shinji

    2005-11-01

    The subjects of this study were 405 Japan Medical Association authorized industrial physicians, Community Industrial Physicians (CIPs), who belonged to the Shinjuku, Nakano, and Suginami Words' regional medical associations in the jurisdiction of the Shinjuku Labor Standards Inspection Office. Between November and December, 2003, the CIPs were mailed a questionnaire requesting information about their affiliations and activities, and as indicators of their willingness to participate in Community Occupational Health Services, they were asked about the pros and cons of having their names published as Industrial Physicians, and/or practitioners for Regional Occupational Health Centers, or Regular Health Checks. 152 replies were received, effective response rate of 37.5%, and among these 94 replies were from CIPs who work as part-time industrial physician. Overall, CIPs attend Community Occupational Health Services (COHS) voluntarily, and wish to participate in them more in the future. CIPs who work as part-time industrial physician have knowledge of working safety and hygiene and are providing advice and guidance on working conditions and environments. Also, they are well informed about support services for small and medium-sized enterprises which is thought to be connected with their willingness to participate in COHS. Furthermore, it is important that part-time CIPs activities are appreciated by their respective place of work.

  11. Facilitators and barriers to occupational health and safety in small and medium-sized enterprises: a descriptive exploratory study in Ontario, Canada.

    Science.gov (United States)

    Nowrouzi, Behdin; Gohar, Basem; Nowrouzi-Kia, Behnam; Garbaczewska, Martyna; Chapovalov, Olena; Myette-Côté, Étienne; Carter, Lorraine

    2016-09-01

    The purpose of this particular study was to test a newly created instrument in describing the facilitators and barriers to occupational health and safety in small and medium-sized enterprises (SMEs) in Ontario, Canada. A cross-sectional design was used to identify the occupational health and safety culture of SMEs in public and private sectors in Ontario. A total of 153 questionnaires were completed. The majority of respondents were female (84%) with a mean age of 49.8 years (SD 10.6). Seventy-four percent were supervisors. Seventy percent of respondents were from the private sector while 30% derived from the public sector including healthcare, community services, and non-profit organizations. Further, conducting regular external safety inspections of the workplace was found to be statistically associated with a safe work environment 2.88 95% CI [1.57, 5.27]. Strategies and training opportunities that focus on how to adapt occupational health and safety legislation to the nature and diversity of SMEs are recommended. Furthermore, employers may use such information to improve safety in their SMEs, while researchers can hopefully use such evidence to develop interventions that are applicable to meeting the occupational health and safety needs of SMEs.

  12. Possibilities and hindrances for prevention of intimate partner violence: perceptions among professionals and decision makers in a Swedish medium-sized town.

    Science.gov (United States)

    Jakobsson, A; von Borgstede, C; Krantz, G; Spak, F; Hensing, G

    2013-09-01

    Intimate partner violence (IPV) is a major public health problem, but few evidence-based prevention programs have yet been implemented. This study explored the perceptions and beliefs of local-level decision makers, social and health-care professionals, and representatives from the police force regarding the possibilities and hindrances for prevention of IPV. An explorative qualitative approach was used, and participants were strategically selected for focus group discussions. The participants, 19 men and 23 women, were professionals or decision makers within health-care services, social welfare, municipal administration, the police force, local industry, and local politicians in a Swedish town of 54,000 inhabitants. The focus group discussions were audio recorded, transcribed verbatim, and thematically analyzed. A manifest content analysis was performed on the text. Preschools, schools, sports associations, workplaces, and the mass media were suggested as possible arenas for prevention measures. The proposed activities included norm building and improved social support structures. Hindrances were conceptualized as societal beliefs and attitudes, shame, silence, gender inequality, the counteracting influence of the media, and lack of resources. The participants demonstrated closeness and distance to IPV, expressed as acceptance or referral of responsibility to others regarding where and by whom prevention measures should be executed. This study gave new insights in the prevailing perceptions of professionals and decision makers of a medium-sized Swedish town, which can be a useful knowledge in future preventive work and contribute to bridge the gap between research and practice.

  13. The determinants of the readiness to let go among senior generation owner-managers of small and medium-sized family businesses

    Directory of Open Access Journals (Sweden)

    Stephan P van der Merwe

    2010-09-01

    Full Text Available The objective of this study was to assess the determinants of the readiness of the senior generation owner-managers to finally transfer the management and control of the family business to the younger generation. Data from 504 questionnaires linked to 81 family businesses were collected and analysed. An Oblimin oblique rotation was carried out on the principal components of the exploratory factor analysis. Five factors with eigen-values greater than one, explaining 62.64 per cent of the variance, were extracted. These five factors describing the theoretical dimensions of the dependent variable were: the senior generation owner-manager’s readiness to let go, and the independent variables of retirement planning, perceived suitability of the successor, estate planning, and the perceived liquidity of the business after the transfer. No significant practical differences relating to these five factors could be found between the perceptions of male and female respondents, the senior and younger generation family members or family members involved in medium-sized or small businesses. Practical recommendations are suggested to ensure a smooth final transfer of the management and control of the business to the younger generation family members.

  14. A simulation study of the energy-efficient options for upgrading and retrofitting a medium-size municipal wastewater treatment plant.

    Science.gov (United States)

    Mucha, Zbigniew; Mikosz, Jerzy

    2016-10-01

    Many municipal wastewater treatment plants are retrofitted with membrane filtration that replaces secondary clarification. Such a solution saves space and improves overall treatment efficiency but at the cost of increased energy consumption and reduced potential for energy recovery from sewage sludge. Thus, the plant takes a step back from reaching energy self-sufficiency. In the presented case study, two alternative upgrade options were simulated for a medium-size municipal wastewater treatment plant in Poland: the first one assumed optimization of the existing bioreactor, and the other - installation of microfiltration membrane units inside the bioreactor. In both cases, anaerobic digestion of waste sludge with biogas utilization is planned. The results have shown that while under both upgrade options, the plant's capacity can be effectively increased by approximately 50%, their effects on the plant's energy balance will be very different. Although the installation of membrane modules accompanied by the construction of anaerobic digestion tanks improves the plant's energy balance, it will remain negative. The option of optimizing the existing biological treatment system produces a positive energy balance with more energy produced from biogas than consumed. Thus, the plant is able to approach energy self-sufficiency. It has been concluded that retrofitting the plants with membrane filtration is not always the best option from the energy balance point of view and it should be preceded with a detailed analysis on a case-by-case basis.

  15. The effect of air pollutants on birth weight in medium-sized towns in the state of São Paulo

    Directory of Open Access Journals (Sweden)

    Veridiana de Paula Santos

    2014-12-01

    Full Text Available OBJECTIVE: To investigate the effect of air pollution on birth weight in a medium-sized town in the State of São Paulo, Southeast Brazil.METHODS: Cross-sectional study using data from live births of mothers residing in São José dos Campos from 2005 to 2009. Data was obtained from the Department of Information and Computing of the Brazilian Unified Health System. Air pollutant data (PM10, SO2, and O3 and daily averages of their concentrations were obtained from the Environmental Sanitation & Technology Company. Statistical analysis was performed by linear and logistic regressions using the Excel and STATA v.7 software programs.RESULTS: Maternal exposure to air pollutants was not associated with low birth weight, with the exception of exposure to SO2 within the last month of pregnancy (OR=1.25; 95% CI=1.00-1.56. Maternal exposure to PM10 and SO2 during the last month of pregnancy led to lower weight at birth (0.28g and 3.15g, respectively for each 1mg/m3 increase in the concentration of these pollutants, but without statistical significance.CONCLUSIONS: This study failed to identify a statistically significant association between the levels of air pollutants and birth weight, with the exception of exposure to SO2 within the last month of pregnancy.

  16. Urban agricultural land use and characterization of mosquito larval habitats in a medium-sized town of Côte d'Ivoire.

    Science.gov (United States)

    Matthys, Barbara; N'Goran, Eliézer K; Koné, Moussa; Koudou, Benjamin G; Vounatsou, Penelope; Cissé, Guéladio; Tschannen, Andres B; Tanner, Marcel; Utzinger, Jürg

    2006-12-01

    Urban agriculture is common across Africa and contributes to the livelihoods of urban dwellers. Some crop systems create suitable mosquito breeding sites and thus might affect malaria transmission. The purpose of this study was to identify, map, and characterize potential mosquito breeding sites in agricultural land use zones in a medium-sized town of western Côte d'Ivoire and to assess risk factors for productive Anopheles breeding sites. Two surveys were carried out; one toward the end of the rainy season and the second one during the dry season. In all identified potential mosquito breeding sites, two experienced entomologists searched for the presence of Anopheles larvae and pupae with a standardized technique. Totals of 369 and 589 sites were found in the rainy and dry seasons, respectively, mainly in vegetable gardens and irrigated rice fields. Anopheles larvae were present in 50.7% and 42.4% of the sites investigated during the rainy and dry seasons, respectively. Typical Anopheles larval habitats were characterized by the presence of algae, the absence of floating vegetation, and the co-occurrence of Culex larvae. The highest Anopheles larval productivity was observed in rice paddies, agricultural trenches between vegetable patches, and irrigation wells. An indirect link could be established between the occurrence of productive Anopheles breeding sites and agricultural land use through specific man-made habitats, in particular agricultural trenches, irrigation wells, and rice paddies. Our findings have important bearings for the epidemiology and control of urban malaria in sub-Saharan Africa.

  17. Ambient air levels of volatile organic compounds (VOC) and nitrogen dioxide (NO{sub 2}) in a medium size city in Northern Spain

    Energy Technology Data Exchange (ETDEWEB)

    Parra, M.A. [Laboratorio Integrado de Calidad Ambiental (LICA), Departamento de Quimica y Edafologia, Facultad de Ciencias, Universidad de Navarra. Irunlarrea 1, 31008, Pamplona, Navarra (Spain)], E-mail: mparravi@alumni.unav.es; Elustondo, D.; Bermejo, R.; Santamaria, J.M. [Laboratorio Integrado de Calidad Ambiental (LICA), Departamento de Quimica y Edafologia, Facultad de Ciencias, Universidad de Navarra. Irunlarrea 1, 31008, Pamplona, Navarra (Spain)

    2009-01-15

    Ambient concentrations of volatile organic compounds (VOC) and nitrogen dioxide (NO{sub 2}) were measured by means of passive sampling at 40 sampling points in a medium-size city in Northern Spain, from June 2006 to June 2007. VOC and NO{sub 2} samplers were analysed by thermal desorption followed by gas chromatography/mass-selective detector and by visible spectrophotometry, respectively. Mean concentrations of benzene, toluene, ethylbenzene, xylenes, propylbenzene, trimethylbenzenes, and NO{sub 2} were 2.84, 13.26, 2.15, 6.01, 0.59, 1.32 and 23.17 {mu}g m{sup -3} respectively, and found to be highly correlated. Their spatial distribution showed high differences in small distances and pointed to traffic as the main emission source of these compounds. The lowest levels of VOC and NO{sub 2} occurred during summer, owing to the increase in solar radiation and to lower traffic densities. Mean concentrations of benzene and NO{sub 2} exceeded the European limits at some of the monitored points.

  18. [Analysis of workplace health promotion and its effect on work ability and health-related quality of life in a medium-sized business].

    Science.gov (United States)

    Biallas, B; Froböse, I; Zöller, M; Wilke, C

    2015-05-01

    This study analyses the effect of workplace health promotion on work ability and health-related quality of life in white-collar and blue-collar workers in a medium-sized business. The intervention group contains 75 subjects with a mean age of 36.6±10.63 years (55 men, 20 women). The participation rate is 47%. White-collar workers show improvement in their health-related quality of life regarding physical and psychological aspects and work ability. Physically inactive employees show improvement in their health-related quality of life regarding physical and psychological aspects as well as context. Active employees only show significant improvement in terms of work ability. In conclusion, the promotion of exercise in the context of occupational health promotion has a positive effect on quality of life and work ability of employees and, thus, is a benefit for both the individual as well as the business itself. © Georg Thieme Verlag KG Stuttgart · New York.

  19. The effect of an electronic medicine dispenser on diversion of buprenorphine-naloxone-experience from a medium-sized Finnish city.

    Science.gov (United States)

    Uosukainen, Hanna; Pentikäinen, Hannu; Tacke, Ulrich

    2013-07-01

    Providing unobserved opioid substitution treatment (OST) safely is a major challenge. This study examined whether electronic medicine dispensers (EMDs) can reduce diversion of take-home buprenorphine-naloxone (BNX) in a medium-sized Finnish city. All BNX treated OST patients in Kuopio received their take-home BNX in EMDs for 4months. EMDs' effect on diversion was investigated using questionnaires completed by patients (n=37) and treatment staff (n=19), by survey at the local needle exchange service and by systematic review of drug screen data from the Kuopio University Hospital. The majority of patients (n=21, 68%) and treatment staff (n=11, 58%) preferred to use EMDs for the safe storage of tablets. Five patients (16%) declared that EMDs had prevented them from diverting BNX. However, EMDs had no detectable effect on the availability or origin of illegal BNX or on the hospital-treated buprenorphine-related health problems. EMDs may improve the safety of storage of take-home BNX, but their ability to prevent diversion needs further research. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. The relative cost-effectiveness of PCNL and ESWL for medium sized (2 cms renal calculi in a tertiary care urological referral centre

    Directory of Open Access Journals (Sweden)

    Pradeep P Rao

    2001-01-01

    Full Text Available There is a paucity of cost-effectiveness studies in India comparing PCNL and ESWL in the treatment of renal cal-culi. We are dependent on costing studies from western literature, although the nature of expenses in developed countries is quite different from those in India. This study compares the two procedures with regards to cost-effec-tiveness & efficacy in clearing medium-sized renal calculi (2.0 cms at our institute. All costs borne by the patient & the institute were taken into account, including equip-ment costs, stay charges & cost of travel incurred, for re-peat visits to the institute. The groups compared had similar stone characteristics & were from our early experience with the two methods. All costing was done at 1998 rates by submitting case sheets to a fresh billing. PCNL, was significantly more efficient at clearing calculi (94% vs 69% than ESWL, but patients needed hospitalization. The re-quirement of ancillary procedures was significantly less with PCNL than ESWL (1 vs 35 and ESWL was more expensive although the difference was not statistically sig-nificant. High initial cost of a lithotripter along with the need for repeated visits to the hospital for clearance of the calculus contribute to the increased cost of ESWL. PCNL ensures clearance of calculi at a single hospital admission with minimal morbidity.

  1. Results from an exploratory study to identify the factors that contribute to success for UK medical device small- and medium-sized enterprises.

    Science.gov (United States)

    Hourd, P C; Williams, D J

    2008-07-01

    This paper reports the results from an exploratory study that sets out to identify and compare the strategic approaches and patterns of business practice employed by 14 UK small- and medium-sized enterprises to achieve success in the medical device sector of the health-care industry. An interview-based survey was used to construct individual case studies of the medical device technology (MDT) companies. A cross-case analysis was performed to search for patterns and themes that cut across these individual cases. Exploratory results revealed the heterogeneity of MDT companies and the distinctive features of the MDT innovation process that emphasize the importance of a strategic approach for achieving milestones in the product development and exploitation process and for creating value for the company and its stakeholders. Recognizing the heterogeneity of MDT companies, these exploratory findings call for further investigation to understand better the influence of components of the MDT innovation process on the commercialization life cycle and value trajectory. This is required to assist start-up or spin-out MDT companies in the UK and worldwide to navigate the critical transitions that determine access to financial and consumer markets and enhance the potential to build a successful business. This will be important not only for bioscience-based companies but also for engineering-based companies aiming to convert their activities into medical devices and the health- and social-care market.

  2. Species diversity and morphometrics of tardigrades from a medium-size city in the Neotropical Region: Santa Rosa (La Pampa, Argentina

    Directory of Open Access Journals (Sweden)

    Peluffo, J. R.

    2007-06-01

    Full Text Available Tardigrade diversity was studied in a medium-sized city in the Neotropical Region: Santa Rosa (La Pampa, Argentina. Samples were collected between February 1999 and January 2000 from lichens and mosses growing on sidewalk trees of the urban and periurban area. Five species of tardigrades were found, i.e., Echiniscus rufoviridis du Bois-Reymond Marcus, 1944, Macrobiotus areolatus Murray, 1907, Ramazzottius oberhaeuseri (Doyère, 1840, Milnesium cf. tardigradum and a non-described species of Macrobiotus. Only one species, M. cf. tardigradum, was found in areas with high levels of vehicle traffic. Results are compared with those from cities in the Nearctic and Palearctic regions. Measurements and pt index values (percentage ratios between the length of the structure considered and the buccal tube length are provided for M. areolatus, R. oberhaeuseri and M. cf. tardigradum. Amongst the characters considered, the pt index for the stylet support insertion shows the least intraspecific variation. This character is also independent from body length and buccal-tube length.

  3. Health-related quality of life and its correlates among Chinese migrants in small- and medium-sized enterprises in two cities of Guangdong.

    Directory of Open Access Journals (Sweden)

    Liming Lu

    Full Text Available OBJECTIVES: To explore the relationship between health-related quality of life (HRQOL status and associated factors among rural-to-urban migrants in China. METHODS: A cross-sectional survey was conducted with 856 rural-to-urban migrants working at small- and medium-size enterprises (SMEs in Shenzhen and Zhongshan City in 2012. Andersen's behavioral model was used as a theoretical framework to exam the relationships among factors affecting HRQOL. Analysis was performed using structural equation modeling (SEM. RESULTS: Workers with statutory working hours, higher wages and less migrant experience had higher HRQOL scores. Need (contracting a disease in the past two weeks and perception of needing health service had the greatest total effect on HRQOL (β = -0.78, followed by enabling (labor contract, insurance purchase, income, physical examination during work and training (β = 0.40, predisposing (age, family separation, education (β = 0.22 and health practices and use of health service (physical exercise weekly, health check-up and use of protective equipments (β = -0.20. CONCLUSIONS: Priority should be given to satisfy the needs of migrant workers, and improve the enabling resources.

  4. Half-sandwich cobalt complexes in the metal-organic chemical vapor deposition process

    Energy Technology Data Exchange (ETDEWEB)

    Georgi, Colin [Technische Universität Chemnitz, Faculty of Natural Science, Institute of Chemistry, Inorganic Chemistry, Chemnitz 09107 (Germany); Hapke, Marko; Thiel, Indre [Leibniz-Institut für Katalyse e.V. an der Universität Rostock (LIKAT), Albert-Einstein-Straße 29a, Rostock 18059 (Germany); Hildebrandt, Alexander [Technische Universität Chemnitz, Faculty of Natural Science, Institute of Chemistry, Inorganic Chemistry, Chemnitz 09107 (Germany); Waechtler, Thomas; Schulz, Stefan E. [Fraunhofer Institute of Electronic Nano Systems (ENAS), Technologie-Campus 3, Chemnitz 09126 (Germany); Technische Universität Chemnitz, Center for Microtechnologies (ZfM), Chemnitz 09107 (Germany); Lang, Heinrich, E-mail: heinrich.lang@chemie.tu-chemnitz.de [Technische Universität Chemnitz, Faculty of Natural Science, Institute of Chemistry, Inorganic Chemistry, Chemnitz 09107 (Germany)

    2015-03-02

    A series of cobalt half-sandwich complexes of type [Co(η{sup 5}-C{sub 5}H{sub 5})(L)(L′)] (1: L, L′ = 1,5-hexadiene; 2: L = P(OEt){sub 3}, L′ = H{sub 2}C=CHSiMe{sub 3}; 3: L = L′ = P(OEt){sub 3}) has been studied regarding their physical properties such as the vapor pressure, decomposition temperature and applicability within the metal-organic chemical vapor deposition (MOCVD) process, with a focus of the influence of the phosphite ligands. It could be shown that an increasing number of P(OEt){sub 3} ligands increases the vapor pressure and thermal stability of the respective organometallic compound. Complex 3 appeared to be a promising MOCVD precursor with a high vapor pressure and hence was deposited onto Si/SiO{sub 2} (100 nm) substrates. The resulting reflective layer is closed, dense and homogeneous, with a slightly granulated surface morphology. X-ray photoelectron spectroscopy (XPS) studies demonstrated the formation of metallic cobalt, cobalt phosphate, cobalt oxide and cobalt carbide. - Highlights: • Thermal studies and vapor pressure measurements of cobalt half-sandwich complexes was carried out. • Chemical vapor deposition with cobalt half-sandwich complexes is reported. • The use of Co-phosphites results in significant phosphorous-doped metallic layers.

  5. Complexing agents in waste waters of Finnish electrolytic and chemical surface treatment plants.

    Science.gov (United States)

    Pirkanniemi, Kari; Vuorio, Anna-Maria; Vilhunen, Sari; Metsärinne, Sirpa; Sillanpää, Mika

    2008-05-01

    Complexing agents are one of the major environmental concerns in electrolytic and chemical surface treatment (ECST) industry; e.g. the EU reference document on the best available technology (BREF) pays special attention to the usage of EDTA. However, no comprehensive studies are available on usage of EDTA or other complexing agents or their load to the receiving waters from ECST industry. In this study, the concentrations of complexing agents were analyzed to get an overview of their usage and load and also to recognize their relevance in the environmental permitting and compliance monitoring of such facilities. Complexing agent concentrations of treated waste water samples of 23 ECST plants with vat volume exceeding 30 m3 was studied. HPLC and GC-MS were used to analyze and identify complexing agent concentrations, ICP-AES to analyze metals, and TOC to analyse the organic load. The number of the plants in this study equals around 50% of such installations in Finland subject to environmental permit as the IPPC directive provides. EDTA, DTPA, and NTA were found in 11 samples out of 23 mainly in rather small concentrations. Their annual load to the receiving waters may be estimated to be 0.3 tons and the total load from Finnish ECST industry can be extrapolated to be up to 1 ton. Compared to the estimated use of 5-10 tons in the industry this finding is rather low, even though in Finland cast-off treatment baths are typically delivered to the hazardous waste treatment plants. Since the load of complexing agents is rather low, the chemical waste water treatment seems to be either capable of reducing complexing agent concentrations to some extent or their usage is lower than expected. On the other hand, it is possible that not all complexing agents were identified from the samples. The metal concentrations and TOC were well hand in hand with concentrations found in the Finnish environmental database, which proves that the samples were of average quality of the waste

  6. Assessing bioavailability of complex chemical mixtures in contaminated soils: Progress made and research needs.

    Science.gov (United States)

    Cipullo, S; Prpich, G; Campo, P; Coulon, F

    2018-02-15

    Understanding the distribution, behaviour and interactions of complex chemical mixtures is key for providing the evidence necessary to make informed decisions and implement robust remediation strategies. Much of the current risk assessment frameworks applied to manage land contamination are based on total contaminant concentrations and the exposure assessments embedded within them do not explicitly address the partitioning and bioavailability of chemical mixtures. These oversights may contribute to an overestimation of both the eco-toxicological effects of the fractions and the mobility of contaminants. In turn, this may limit the efficacy of risk frameworks to inform targeted and proportionate remediation strategies. In this review we analyse the science surrounding bioavailability, its regulatory inclusion and the challenges of incorporating bioavailability in decision making process. While a number of physical and chemical techniques have proven to be valuable tools for estimating bioavailability of organic and inorganic contaminants in soils, doubts have been cast on its implementation into risk management soil frameworks mainly due to a general disagreement on the interchangeable use of bioavailability and bioaccessibility, and the associated methods which are still not standardised. This review focuses on the role of biotic and abiotic factors affecting bioavailability along with soil physicochemical properties and contaminant composition. We also included advantages and disadvantages of different extraction techniques and their implications for bioavailability quantitative estimation. In order to move forward the integration of bioavailability into site-specific risk assessments we should (1) account for soil and contaminant physicochemical characteristics and their effect on bioavailability; (2) evaluate receptor's potential exposure and uptake based on mild-extraction; (3) adopt a combined approach where chemical-techniques are used along with biological

  7. Comparison of runaway electron generation parameters in small, medium-sized and large tokamaks—A survey of experiments in COMPASS, TCV, ASDEX-Upgrade and JET

    Science.gov (United States)

    Plyusnin, V. V.; Reux, C.; Kiptily, V. G.; Pautasso, G.; Decker, J.; Papp, G.; Kallenbach, A.; Weinzettl, V.; Mlynar, J.; Coda, S.; Riccardo, V.; Lomas, P.; Jachmich, S.; Shevelev, A. E.; Alper, B.; Khilkevitch, E.; Martin, Y.; Dux, R.; Fuchs, C.; Duval, B.; Brix, M.; Tardini, G.; Maraschek, M.; Treutterer, W.; Giannone, L.; Mlynek, A.; Ficker, O.; Martin, P.; Gerasimov, S.; Potzel, S.; Paprok, R.; McCarthy, P. J.; Imrisek, M.; Boboc, A.; Lackner, K.; Fernandes, A.; Havlicek, J.; Giacomelli, L.; Vlainic, M.; Nocente, M.; Kruezi, U.; COMPASS team; TCV team; ASDEX-Upgrade team; EUROFusion MST1 Team; contributors, JET

    2018-01-01

    This paper presents a survey of the experiments on runaway electrons (RE) carried out recently in frames of EUROFusion Consortium in different tokamaks: COMPASS, ASDEX-Upgrade, TCV and JET. Massive gas injection (MGI) has been used in different scenarios for RE generation in small and medium-sized tokamaks to elaborate the most efficient and reliable ones for future RE experiments. New data on RE generated at disruptions in COMPASS and ASDEX-Upgrade was collected and added to the JET database. Different accessible parameters of disruptions, such as current quench rate, conversion rate of plasma current into runaways, etc have been analysed for each tokamak and compared to JET data. It was shown, that tokamaks with larger geometrical sizes provide the wider limits for spatial and temporal variation of plasma parameters during disruptions, thus extending the parameter space for RE generation. The second part of experiments was dedicated to study of RE generation in stationary discharges in COMPASS, TCV and JET. Injection of Ne/Ar have been used to mock-up the JET MGI runaway suppression experiments. Secondary RE avalanching was identified and quantified for the first time in the TCV tokamak in RE generating discharges after massive Ne injection. Simulations of the primary RE generation and secondary avalanching dynamics in stationary discharges has demonstrated that RE current fraction created via avalanching could achieve up to 70–75% of the total plasma current in TCV. Relaxations which are reminiscent the phenomena associated to the kinetic instability driven by RE have been detected in RE discharges in TCV. Macroscopic parameters of RE dominating discharges in TCV before and after onset of the instability fit well to the empirical instability criterion, which was established in the early tokamaks and examined by results of recent numerical simulations.

  8. Comparing capture-recapture methods for estimation of the size of small and medium-sized populations using empirical data on commercial turkey farms in Canada.

    Science.gov (United States)

    El Allaki, Farouk; Christensen, Jette; Vallières, André

    2015-06-01

    The study objectives were (1) to conduct a systematic review of the performance of capture-recapture methods; (2) to use empirical data to estimate population size in a small-sized population (turkey breeder farms) and a medium-sized population (meat turkey farms) by applying two-source capture-recapture methods (the Lincoln-Petersen, the Chapman, and Chao's lower-bound estimators) and multi-source capture-recapture methods (the log-linear modeling and sample coverage approaches); and (3) to compare the performance of these methods in predicting the true population sizes (2007 data). Our set-up was unique in that we knew the population sizes for turkey breeder farms (99) and meat turkey farms (592) in Canada in 2007, which we applied as our true population sizes, and had surveillance data from the Canadian Notifiable Avian Influenza Surveillance System (2008-2012). We defined each calendar year of sampling as a data source. We confirmed that the two-source capture-recapture methods were sensitive to the violation of the local independence assumption. The log-linear modeling and sample coverage approaches yielded estimates that were closer to the true population sizes than were the estimates provided by the two-source methods for both populations. The performance of both multi-source capture-recapture methods depended on the number of data sources analyzed and the size of the population. Simulation studies are recommended to better understand the limits of each multi-source capture-recapture method. Crown Copyright © 2014. Published by Elsevier B.V. All rights reserved.

  9. The role of HIV/AIDS committees in effective workplace governance of HIV/AIDS in South African small and medium-sized enterprises (SMEs).

    Science.gov (United States)

    Vaas, Jocelyn R

    2008-04-01

    The primary purpose of this study was to assess the role, status and scope of workplace HIV/AIDS committees as a means of effective workplace governance of the HIV/AIDS impact, and their role in extending social protective HIV/AIDS-related rights to employees. In-depth qualitative case studies were conducted in five South African small and medium-sized enterprises (SMEs) that were actively implementing HIV/AIDS policies and programmes. Companies commonly implemented HIV/AIDS policies and programmes through a workplace committee dedicated to HIV/AIDS or a generic committee dealing with issues other than HIV/ AIDS. Management, through the human resources department and the occupational health practitioner often drove initial policy formulation, and had virtually sole control of the HIV/AIDS budget. Employee members of committees were mostly volunteers, and were often production or blue collar employees, while there was a notable lack of participation by white-collar employees, line management and trade unions. While the powers of workplace committees were largely consultative, employee committee members often managed in an indirect manner to secure and extend social protective rights on HIV/AIDS to employees, and monitor their effective implementation in practice. In the interim, workplace committees represented one of the best means to facilitate more effective workplace HIV/AIDS governance. However, the increased demands on collective bargaining as a result of an anticipated rises in AIDS-related morbidity and mortality might prove to be beyond the scope of such voluntary committees in the longer term.

  10. Influence of large wood on channel hydraulics, sediment (dis-)connectivity and channel morphology in a medium-sized mixed-load Austrian stream

    Science.gov (United States)

    Schuchardt, Anne; Pöppl, Ronald; Morche, David

    2017-04-01

    It is widely known that large wood (LW) in rivers alters channel hydraulics, channel morphology and sediment transport. Channel spanning LW can create blocking barriers, steps and dams which store sediment and organic material in small reservoirs for the lifetime of the damming structure. Otherwise, the breach of LW key logs and jams makes the long term stored sediment available for fluvial transport. However, detailed field measurements on the distribution of LW and its influence on hydraulic variables, channel morphology and (especially) sediment connectivity are still rare, thus further constituting the major aim of this study. The study was performed along the lower reaches ( 6 km) of the Fugnitz River, a mixed-load, medium-sized (catchment area 130 km2) single-thread perennial stream, located in the Bohemian Massif, Austria. The spatial distribution and characterization of LW (>1 m in length and >10 cm in diameter) was examined along the main stem via field mapping and dGPS measurements. Hydraulic channel parameters (e.g. channel gradient, cross-sectional profiles) and volumes of retained sediment were determined via field measurements, while channel morphology incl. indications of LW-induced geomorphic processes (e.g. bank undercutting, scouring) was obtained via geomorphic mapping. Flow characteristics and bed load transport rates were measured using an Ott-Nautilus and a portable Helley-Smith bed load sampler during different water stages. Additionally, bed sediment textures were examined by performing pebble count analyses. In-channel LW accumulations (total volume of 588 m3) were primarily observed in meandering river reaches as well as in reaches with steep hillslopes. 36% of all LW accumulations were classified as dams, steps or deflectors altering flow conditions or creating backwater areas decreasing sediment connectivity. Highest volumes of sediment storage (total volume of 26 m3) have been primarily recorded at locations where bank erosion processes

  11. The control system of the 12-m medium-size telescope prototype: a test-ground for the CTA array control

    Science.gov (United States)

    Oya, I.; Anguner, E. A.; Behera, B.; Birsin, E.; Fuessling, M.; Lindemann, R.; Melkumyan, D.; Schlenstedt, S.; Schmidt, T.; Schwanke, U.; Sternberger, R.; Wegner, P.; Wiesand, S.

    2014-07-01

    The Cherenkov Telescope Array (CTA) will be the next generation ground-based very-high energy -ray observatory. CTA will consist of two arrays: one in the Northern hemisphere composed of about 20 telescopes, and the other one in the Southern hemisphere composed of about 100 telescopes, both arrays containing telescopes of different sizes and types and in addition numerous auxiliary devices. In order to provide a test-ground for the CTA array control, the steering software of the 12-m medium size telescope (MST) prototype deployed in Berlin has been implemented using the tools and design concepts under consideration to be used for the control of the CTA array. The prototype control system is implemented based on the Atacama Large Millimeter/submillimeter Array (ALMA) Common Software (ACS) control middleware, with components implemented in Java, C++ and Python. The interfacing to the hardware is standardized via the Object Linking and Embedding for Process Control Unified Architecture (OPC UA). In order to access the OPC UA servers from the ACS framework in a common way, a library has been developed that allows to tie the OPC UA server nodes, methods and events to the equivalents in ACS components. The front-end of the archive system is able to identify the deployed components and to perform the sampling of the monitoring points of each component following time and value change triggers according to the selected configurations. The back-end of the archive system of the prototype is composed by two different databases: MySQL and MongoDB. MySQL has been selected as storage of the system configurations, while MongoDB is used to have an efficient storage of device monitoring data, CCD images, logging and alarm information. In this contribution, the details and conclusions on the implementation of the control software of the MST prototype are presented.

  12. Hydrologic Evaluation of Six High Resolution Satellite Precipitation Products in Capturing Extreme Precipitation and Streamflow over a Medium-Sized Basin in China

    Directory of Open Access Journals (Sweden)

    Shanhu Jiang

    2017-12-01

    Full Text Available Satellite precipitation products (SPPs are critical data sources for hydrological prediction and extreme event monitoring, especially for ungauged basins. This study conducted a comprehensive hydrological evaluation of six mainstream SPPs (i.e., TMPA 3B42RT, CMORPH-RT, PERSIANN-RT, TMPA 3B42V7, CMORPH-CRT, and PERSIANN-CDR over humid Xixian basin in central eastern China for a period of 14 years (2000–2013. The evaluation specifically focused on the performance of the six SSPs in capturing precipitation and streamflow extremes. Results show that the two post-real-time research products of TMPA 3B42V7 and CMORPH-CRT exhibit much better performance than that of their corresponding real-time SPPs for precipitation estimation at daily and monthly time scales. By contrast, the newly released post-real-time research product PERSIANN-CDR insignificantly improves precipitation estimates compared with the real-time PERSIANN-RT does at daily time scale. The daily streamflow simulation of TMPA 3B42V7 fits best with the observed streamflow series among those of the six SPPs. The three month-to-month gauge-adjusted post-real-time research products can simulate acceptable monthly runoff series. TMPA 3B42V7 and CMORPH-CRT present good performance in capturing precipitation and streamflow extremes, although they still exhibit non-ignorable deviation and occurrence time inconsistency problems compared with gauge-based results. Caution should be observed when using the current TMPA, CMORPH, and PERSIANN products for monitoring and predicting extreme precipitation and flood at such medium-sized basin. This work will be valuable for the utilization of SPPs in extreme precipitation monitoring, streamflow forecasting, and water resource management in other regions with similar climate and topography characteristics.

  13. Decontamination Efficacy of Three Commercial-Off-The-Shelf (COTS) Sporicidal Disinfectants on Medium-Sized Panels Contaminated with Surrogate Spores of Bacillus anthracis

    Science.gov (United States)

    Sabol, Jonathan P.

    2014-01-01

    In the event of a wide area release and contamination of a biological agent in an outdoor environment and to building exteriors, decontamination is likely to consume the Nation’s remediation capacity, requiring years to cleanup, and leading to incalculable economic losses. This is in part due to scant body of efficacy data on surface areas larger than those studied in a typical laboratory (5×10-cm), resulting in low confidence for operational considerations in sampling and quantitative measurements of prospective technologies recruited in effective cleanup and restoration response. In addition to well-documented fumigation-based cleanup efforts, agencies responsible for mitigation of contaminated sites are exploring alternative methods for decontamination including combinations of disposal of contaminated items, source reduction by vacuuming, mechanical scrubbing, and low-technology alternatives such as pH-adjusted bleach pressure wash. If proven effective, a pressure wash-based removal of Bacillus anthracis spores from building surfaces with readily available equipment will significantly increase the readiness of Federal agencies to meet the daunting challenge of restoration and cleanup effort following a wide-area biological release. In this inter-agency study, the efficacy of commercial-of-the-shelf sporicidal disinfectants applied using backpack sprayers was evaluated in decontamination of spores on the surfaces of medium-sized (∼1.2 m2) panels of steel, pressure-treated (PT) lumber, and brick veneer. Of the three disinfectants, pH-amended bleach, Peridox, and CASCAD evaluated; CASCAD was found to be the most effective in decontamination of spores from all three panel surface types. PMID:24940605

  14. Leveraging effects of triple bottom lines business model on the building and construction small and medium-sized enterprises’ market performance

    Directory of Open Access Journals (Sweden)

    Boniface Okanga

    2017-01-01

    Full Text Available Orientation: Embracement of triple bottom line reporting as a driver of a firm’s sustainability is a paradox puzzling most contemporary business executives.Research purpose: The purpose of this research is to examine how effective alignment of the triple bottom line business model with building and construction operational activities leverages effective market performance of the small and medium-sized enterprises (SMEs in the building and construction industry, so as to identify major paradoxes and the remedial business model that can be suggested.Research design, approach and method: The study uses interpretivist research paradigm and exploratory qualitative research method to explore the opinions and perceptions of 30 judgementally drawn participants comprising managers and supervisors from 30 building and construction SMEs in Gauteng and KwaZulu-Natal provinces. Thematic analysis was used in the evaluation and interpretation of the interview data collected using a semi-structured interview guide.Main findings: A seemingly greater preponderance to pursue profitability at the expense of people and planet bottom lines was found to be common among most of the SMEs during the initial stages of their establishments and growth because of the need to attain the usually essential initial financial sustainability. Even though on attaining financial sustainability, some of the SMEs strive to achieve all the three bottom lines, most of the undertaken initiatives are often only aimed at improving compliance with relevant building and construction legislations.Managerial implications: The study suggests a modified triple bottom line business model that the SMEs in the building and construction industry can replicate to effectively apply triple bottom line reporting as an edifier for effective market performance.Contributions: The study offers a new theory for measuring the leveraging effects of the triple bottom line business model on the building and

  15. Complexing agents and pH influence on chemical durability of type I moulded glass containers.

    Science.gov (United States)

    Biavati, Alberto; Poncini, Michele; Ferrarini, Arianna; Favaro, Nicola; Scarpa, Martina; Vallotto, Marta

    2017-06-16

    Among the factors that affect the glass surface chemical durability, pH and complexing agents presence in aqueous solution have the main role (1). Glass surface attack can be also related to the delamination issue with glass particles appearance in the pharmaceutical preparation. A few methods to check for glass containers delamination propensity and some control guidelines have been proposed (2,3). The present study emphasizes the possible synergy between a few complexing agents with pH on the borosilicate glass chemical durability. Hydrolytic attack was performed in small volume 23 ml type I glass containers autoclaved according to EP or USP for 1 hour at 121°C, in order to enhance the chemical attack due to time, temperature and the unfavourable surface/volume ratio. 0,048 M or 0.024 M (moles/liter) solutions of the acids citric, glutaric, acetic, EDTA (ethylenediaminetetraacetic acid) and sodium phosphate with water for comparison, were used for the trials. The pH was adjusted ± 0,05 units at fixed values 5,5-6,6-7-7,4-8-9 by LiOH diluted solution. Since silicon is the main glass network former, silicon release into the attack solutions was chosen as the main index of the glass surface attack and analysed by ICPAES. The work was completed by the analysis of the silicon release in the worst attack conditions, of moulded glass, soda lime type II and tubing borosilicate glass vials to compare different glass compositions and forming technologies. Surface analysis by SEM was finally performed to check for the surface status after the worst chemical attack condition by citric acid. Copyright © 2017, Parenteral Drug Association.

  16. Chemical and toxicological characterization of an unresolved complex mixture-rich biodegraded crude oil.

    Science.gov (United States)

    Melbye, Alf G; Brakstad, Odd G; Hokstad, Jorunn N; Gregersen, Inger K; Hansen, Bjørn H; Booth, Andy M; Rowland, Steven J; Tollefsen, Knut E

    2009-09-01

    Chemical and toxicological characterization of unresolved complex mixtures in the water-soluble fraction of an artificially weathered Norwegian Sea crude oil was determined by a combination of chemical analysis and toxicity testing in fish in vitro bioassays. The water-soluble fraction of the crude oil was separated into 14 increasingly polar fractions by preparative high-pressure liquid chromatography. The in vitro toxicity (7-ethoxyresorufin O-deethylase activity, estrogenicity, and metabolic inhibition) of these fractions was characterized in a primary culture of liver cells (hepatocytes) from rainbow trout (Oncorhynchus mykiss). The main contributor to toxicity was one of the most polar fractions, accounting gravimetrically for more than 70% of the organic material in the water-soluble fraction and dominated by an unresolved complex mixture. Chemical analysis by gas chromatography-mass spectrometry and comprehensive two-dimensional gas chromatography-time of flight-mass spectrometry identified a large number of cyclic and aromatic sulfoxide compounds and low amounts of benzothiophenes (crude oil (e.g., naphthalenes, polycyclic aromatic hydrocarbons, and alkylated phenols) eluted in less polar fractions, characterized by somewhat lower toxicity. Normalization of in vitro responses to the mass in each fraction demonstrated a more even distribution of toxicity, indicating that toxicity in the individual fractions was related to the amount of material present. Although polar and nonpolar compounds contribute additively to crude oil toxicity, the water-soluble fraction was dominated by polar compounds because of their high aqueous solubility and the high oil-water loading. Under these conditions, the polar unresolved complex mixture-rich fraction might account for a large portion of crude oil toxicity because of its high abundance in the water-soluble fraction.

  17. Full simulation of chiral random matrix theory at nonzero chemical potential by complex Langevin

    Science.gov (United States)

    Mollgaard, A.; Splittorff, K.

    2015-02-01

    It is demonstrated that the complex Langevin method can simulate chiral random matrix theory at nonzero chemical potential. The successful match with the analytic prediction for the chiral condensate is established through a shift of matrix integration variables and choosing a polar representation for the new matrix elements before complexification. Furthermore, we test the proposal to work with a Langevin-time-dependent quark mass and find that it allows us to control the fluctuations of the phase of the fermion determinant throughout the Langevin trajectory.

  18. Reduction of uranyl carbonate and hydroxyl complexes and neptunyl carbonate complexes studied with chemical-electrochemical methods and rixs spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Butorin, Sergei; Nordgren, Joseph [Uppsala Univ. (Sweden); Ollila, Kaija [VTT Processes, Jyvaeskylae (Finland); Albinsson, Yngve [Chalmers Univ. of Technology, Goeteborg (Sweden); Werme, Lars [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden)

    2003-10-01

    . Once these actinides have been mobilised through oxidation, they can migrate away from this potentially oxidising region and will encounter an oxygen free, reducing environment caused by the anaerobic corrosion of the cast iron insert. The actinyl species are no longer thermodynamically stable and reduction to the tetravalent state will be possible. There is, however, an open question whether the reduction kinetics will be sufficiently high to cause reduction in solution and if sorption onto the corroding iron surface will be accompanied by an electron transfer sufficiently rapid to reduce the actinide back to the tetravalent state. This report contains the results of experimental studies of uranium reduction-depletion from water solutions in the presence of corroding iron and spectroscopic studies of the oxidation state of uranium and neptunium sorbed/precipitated onto iron under oxygen free conditions using resonant inelastic soft x-ray scattering (RIXS) spectroscopy. The RIXS measurements show that at least partial reduction of both uranyl carbonate complexes and neptunyl carbonate complexes take place on the corroding iron surface. The chemical/electrochemical measurements indicate that reduction of uranyl carbonate complexes also take place in solution in a system containing corroding iron, i.e. sorption onto the iron/iron oxide surface may not be necessary in order for reduction to take place. Reduction of uranyl hydroxyl complexes was also found to take place in solution, but at a rate that was noticeably lower than for the uranyl carbonate complexes.

  19. Tailoring the physical properties of Ni-based single-phase equiatomic alloys by modifying the chemical complexity

    National Research Council Canada - National Science Library

    Jin, K; Sales, B C; Stocks, G M; Samolyuk, G D; Daene, M; Weber, W J; Zhang, Y; Bei, H

    2016-01-01

    Equiatomic alloys (e.g. high entropy alloys) have recently attracted considerable interest due to their exceptional properties, which might be closely related to their extreme disorder induced by the chemical complexity...

  20. Chemical Frustration. A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Fredrickson, Daniel C [Univ. of Wisconsin, Madison, WI (United States)

    2015-06-23

    Final technical report for "Chemical Frustration: A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases" funded by the Office of Science through the Materials Chemistry Program of the Office of Basic Energy Sciences.

  1. Chemical Diversity and Complexity of Scotch Whisky as Revealed by High-Resolution Mass Spectrometry.

    Science.gov (United States)

    Kew, Will; Goodall, Ian; Clarke, David; Uhrín, Dušan

    2017-01-01

    Scotch Whisky is an important product, both culturally and economically. Chemically, Scotch Whisky is a complex mixture, which comprises thousands of compounds, the nature of which are largely unknown. Here, we present a thorough overview of the chemistry of Scotch Whisky as observed by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Eighty-five whiskies, representing the majority of Scotch Whisky produced and sold, were analyzed by untargeted high-resolution mass spectrometry. Thousands of chemical formulae were assigned for each sample based on parts-per-billion mass accuracy of FT-ICR MS spectra. For the first time, isotopic fine structure analysis was used to confirm the assignment of high molecular weight CHOS species in Scotch Whisky. The assigned spectra were compared using a number of visualization techniques, including van Krevelen diagrams, double bond equivalence (DBE) plots, as well as heteroatomic compound class distributions. Additionally, multivariate analysis, including PCA and OPLS-DA, was used to interpret the data, with key compounds identified for discriminating between types of whisky (blend or malt) or maturation wood type. FT-ICR MS analysis of Scotch Whisky was shown to be of significant potential in further understanding of the complexity of mature spirit drinks and as a tool for investigating the chemistry of the maturation processes. Graphical Abstract ᅟ.

  2. Health and well-being in small and medium-sized enterprises (SMEs). What public health support do SMEs really need?

    Science.gov (United States)

    Holt, Maxine; Powell, Susan

    2015-01-01

    Health and well-being in the workplace is a concept that is understood as a fundamental business case for a productive, happy and healthy workforce. The workplace is also a setting by which knowledge and skills about health can be disseminated to assist people, in improving their health and well-being. Public health professionals are in a position to develop workplace health and well-being interventions, which support those in jobs and those seeking employment. They can also influence the extent to which work and the workplace affects health and well-being outcomes. This article aims to identify the main health and well-being needs of a sample of small and medium-sized enterprises (SMEs) across Greater Manchester and the support that public health professionals can offer. The research adopted a Health Needs Assessment (HNA) approach using convenience and opportunistic sampling methods, from the list of SMEs in Greater Manchester. The SMEs varied in size and type of business, and 91 telephone interviews, using semi-structured questions, were used to collect data which identified the health and well-being needs of a sample of SMEs in Greater Manchester. This research resulted in qualitative data using thematic analysis. Two key themes emerged from the study. Acute seasonal sickness was the most pressing reason for employee absence from work (viruses, flu, seasonal disorders) for the SMEs in this research. This accumulated to the theme of sickness presenteeism. This research highlighted that employees will present at work with acute illness that requires rest, is easily transmitted to other employees and most likely will take a longer time to recover from as cross infection and re-infection occur. A subsidiary theme was that of authenticity and the reporting of sickness, contributing further to sickness presenteeism as employees seek to legitimise their illness. This article provides issues which are specific to SMEs in Greater Manchester. In particular, the pressing

  3. A framework for assessing hydrological regime sensitivity to climate change in a convective rainfall environment: a case study of two medium-sized eastern Mediterranean catchments, Israel

    Directory of Open Access Journals (Sweden)

    N. Peleg

    2015-01-01

    Full Text Available A modeling framework is formulated and applied to assess the sensitivity of the hydrological regime of two catchments in a convective rainfall environment with respect to projected climate change. The study uses likely rainfall scenarios with high spatiotemporal resolution that are dependent on projected changes in the driving regional meteorological synoptic systems. The framework was applied to a case study in two medium-sized Mediterranean catchments in Israel, affected by convective rainfall, by combining the HiReS-WG rainfall generator and the SAC-SMA hydrological model. The projected climate change impact on the hydrological regime was examined for the RCP4.5 and RCP8.5 emission scenarios, comparing the historical (beginning of the 21st century and future (mid-21st-century periods from three general circulation model simulations available from CMIP5. Focusing on changes in the occurrence frequency of regional synoptic systems and their impact on rainfall and streamflow patterns, we find that the mean annual rainfall over the catchments is projected to be reduced by 15% (outer range 2–23% and 18% (7–25% for the RCP4.5 sand RCP8.5 emission scenarios, respectively. The mean annual streamflow volumes are projected to be reduced by 45% (10–60% and 47% (16–66%. The average events' streamflow volumes for a given event rainfall depth are projected to be lower by a factor of 1.4–2.1. Moreover, the streamflow season in these ephemeral streams is projected to be shorter by 22% and 26–28% for the RCP4.5 and RCP8.5, respectively. The amplification in reduction of streamflow volumes relative to rainfall amounts is related to the projected reduction in soil moisture, as a result of fewer rainfall events and longer dry spells between rainfall events during the wet season. The dominant factors for the projected reduction in rainfall amount were the reduction in occurrence of wet synoptic systems and the shortening of the wet synoptic systems

  4. Medium-Sized Mammals around a Radioactive Liquid Waste Lagoon at Los Alamos National Laboratory: Uptake of Contaminants and Evaluation of Radio-Frequency Identification Technology

    Energy Technology Data Exchange (ETDEWEB)

    Leslie A. Hansen; Phil R. Fresquez; Rhonda J. Robinson; John D. Huchton; Teralene S. Foxx

    1999-11-01

    Use of a radioactive liquid waste lagoon by medium-sized mammals and levels of tritium, other selected radionuclides, and metals in biological tissues of the animals were documented at Technical Area 53 (TA-53) of Los Alamos National Laboratory during 1997 and 1998. Rock squirrel (Spermophilus variegates), raccoon (Procyon lotor), striped skunk (Mephitis mephitis), and bobcat (Lynx rufus) were captured at TA-53 and at a control site on the Santa Fe National Forest. Captured animals were anesthetized and marked with radio-frequency identification (RFD) tags and/or ear tags. We collected urine and hair samples for tritium and metals (aluminum, antimony, arsenic, barium, beryllium, cadmium, chromium, copper, lead, mercury, nickel, selenium, silver, and thallium) analyses, respectively. In addition, muscle and bone samples from two rock squirrels collected from each of TA-53, perimeter, and regional background sites were tested for tritium, {sup 137}Cs, {sup 90}Sr, {sup 238}Pu, {sup 239,240}Pu, {sup 241}Am, and total uranium. Animals at TA-53 were monitored entering and leaving the lagoon area using a RFID monitor to read identification numbers from the RFID tags of marked animals and a separate camera system to photograph all animals passing through the monitor. Cottontail rabbit (Sylvilagus spp.), rock squirrel, and raccoon were the species most frequently photographed going through the RFID monitor. Less than half of all marked animals in the lagoon area were detected using the lagoon. Male and female rock squirrels from the lagoon area had significantly higher tritium concentrations compared to rock squirrels from the control area. Metals tested were not significantly higher in rock squirrels from TA-53, although there was a trend toward increased levels of lead in some individuals at TA-53. Muscle and bone samples from squirrels in the lagoon area appeared to have higher levels of tritium, total uranium, and {sup 137}Cs than samples collected from perimeter and

  5. The complex interaction between marine debris and toxic chemicals in the ocean.

    Science.gov (United States)

    Engler, Richard E

    2012-11-20

    Marine debris, especially plastic debris, is widely recognized as a global environmental problem. There has been substantial research on the impacts of plastic marine debris, such as entanglement and ingestion. These impacts are largely due to the physical presence of plastic debris. In recent years there has been an increasing focus on the impacts of toxic chemicals as they relate to plastic debris. Some plastic debris acts as a source of toxic chemicals: substances that were added to the plastic during manufacturing leach from plastic debris. Plastic debris also acts as a sink for toxic chemicals. Plastic sorbs persistent, bioaccumulative, and toxic substances (PBTs), such as polychlorinated biphenyls (PCBs) and dioxins, from the water or sediment. These PBTs may desorb when the plastic is ingested by any of a variety of marine species. This broad look at the current research suggests that while there is significant uncertainty and complexity in the kinetics and thermodynamics of the interaction, plastic debris appears to act as a vector transferring PBTs from the water to the food web, increasing risk throughout the marine food web, including humans. Because of the extremely long lifetime of plastic and PBTs in the ocean, prevention strategies are vital to minimizing these risks.

  6. Computer program for calculation of complex chemical equilibrium compositions and applications. Part 1: Analysis

    Science.gov (United States)

    Gordon, Sanford; Mcbride, Bonnie J.

    1994-01-01

    This report presents the latest in a number of versions of chemical equilibrium and applications programs developed at the NASA Lewis Research Center over more than 40 years. These programs have changed over the years to include additional features and improved calculation techniques and to take advantage of constantly improving computer capabilities. The minimization-of-free-energy approach to chemical equilibrium calculations has been used in all versions of the program since 1967. The two principal purposes of this report are presented in two parts. The first purpose, which is accomplished here in part 1, is to present in detail a number of topics of general interest in complex equilibrium calculations. These topics include mathematical analyses and techniques for obtaining chemical equilibrium; formulas for obtaining thermodynamic and transport mixture properties and thermodynamic derivatives; criteria for inclusion of condensed phases; calculations at a triple point; inclusion of ionized species; and various applications, such as constant-pressure or constant-volume combustion, rocket performance based on either a finite- or infinite-chamber-area model, shock wave calculations, and Chapman-Jouguet detonations. The second purpose of this report, to facilitate the use of the computer code, is accomplished in part 2, entitled 'Users Manual and Program Description'. Various aspects of the computer code are discussed, and a number of examples are given to illustrate its versatility.

  7. ATSDR evaluation of health effects of chemicals. IV. Polycyclic aromatic hydrocarbons (PAHs): understanding a complex problem.

    Science.gov (United States)

    Mumtaz, M M; George, J D; Gold, K W; Cibulas, W; DeRosa, C T

    1996-01-01

    Polycyclic Aromatic Hydrocarbons (PAHs) are a group of chemicals that are formed during the incomplete burning of coal, oil, gas, wood, garbage, or other organic substances, such as tobacco and charbroiled meat. There are more than 100 PAHs. PAHs generally occur as complex mixtures (for example, as part of products such as soot), not as single compounds. PAHs are found throughout the environment in the air, water, and soil. As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals, including PAHs (ATSDR, 1995), found at facilities on the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) and which pose the most significant potential threat to human health, as determined by ATSDR and the Environmental Protection Agency (EPA). These profiles include information on health effects of chemicals from different routes and durations of exposure, their potential for exposure, regulations and advisories, and the adequacy of the existing database. Assessing the health effects of PAHs is a major challenge because environmental exposures to these chemicals are usually to complex mixtures of PAHs with other chemicals. The biological consequences of human exposure to mixtures of PAHs depend on the toxicity, carcinogenic and noncarcinogenic, of the individual components of the mixture, the types of interactions among them, and confounding factors that are not thoroughly understood. Also identified are components of exposure and health effects research needed on PAHs that will allow estimation of realistic human health risks posed by exposures to PAHs. The exposure assessment component of research should focus on (1) development of reliable analytical methods for the determination of bioavailable PAHs following ingestion, (2) estimation of bioavailable PAHs from environmental media, particularly the determination of particle-bound PAHs, (3

  8. Quantum-chemical analysis of formation reactions of Со2+ complexes

    Directory of Open Access Journals (Sweden)

    Viktor F. Vargalyuk

    2017-11-01

    Full Text Available Based on the analysis of quantum chemical calculations results (GAMESS, density functional theory, B3LYP method as to coordination compounds of Co2+ions with H2O, NH3, OH–, F–, Cl–, Br–, I–, CN–, Ac–, Ak– generally given by [Co(H2O6–nLn]2+nx, it has been demonstrated that within the selected series of ligands, there is no correlation between the amount of energy of monosubstituted cobalt aqua complexes formation(∆Е and pK1,just like between the effective nuclear charge of the central atom (z*Со and pK1. According to the behavior of ∆Е and z*Со,we identified two groups of ligands. The first group (OH–, F–, Ac–, Ak–, CN–, NH3 demonstrates logical ∆Е decrease caused by the growth of z*Со. On the contrary, the second group (Cl–, Br–, I– demonstrates ∆Е increase caused by the growth of z*Со. This phenomenon is explained by the change in electronegativity and polarizability of donor atoms in groups and periods of the periodic table. It is established that linear correlations given by lgK = A + B·z*Со can be actualized only for complexes having ligands with similar donor atoms. Referring to the literature on stepwise complex formation of hydroxide, amine and chloride cobalt complexes in combination with z*Со calculations results, we determined A and B constants of lgK, z*Со-correlations for the atoms of oxygen (30.2, –17.7; nitrogen (125.4, –69.9 and chlorine (–6.3, 5.8. The existence of the detected correlation series enables us to lean on lgK,z*М–dependence parameters for the fixed donor atom and to determine Kn values for various complexes with complex-based ligands using calculations and z*М data. This applies to complexes having central atoms of the same nature as well as simple monodentate ligands. The mentioned approach was used to calculate the stability constants for acrylate cobalt complexes (lgK1 = 1.2 и lgК2 = 4.3, which are not covered in literature.

  9. Lipid complex effect on fatty acid profile and chemical composition of cow milk and cheese.

    Science.gov (United States)

    Bodkowski, R; Czyż, K; Kupczyński, R; Patkowska-Sokoła, B; Nowakowski, P; Wiliczkiewicz, A

    2016-01-01

    The effect of administration of lipid complex (LC) on cow milk and cheese characteristics was studied. Lipid complex was elaborated based on grapeseed oil with synthesized conjugated linoleic acid (CLA) and Atlantic mackerel oil enriched in n-3 fatty acids. The 4-wk experiment was conducted on 30 Polish Holstein Friesian cows. The experimental group cow diet was supplemented with 400 g/d of LC (containing 38% CLA, and eicosapentaenoic acid + docosahexaenoic acid in a relative amount of 36.5%) on a humic-mineral carrier. The chemical composition and fatty acid profile of milk and rennet cheese from raw fresh milk were analyzed. Lipid complex supplementation of the total mixed ration had no effect on milk yield and milk composition, except fat content, which decreased from 4.6 to 4.1%, a 10.9% decrease. Milk from cows treated with LC had greater relative amounts of unsaturated fatty acids, particularly polyunsaturated fatty acids, and lesser relative amounts of saturated fatty acids. Lipid complex addition changed milk fat fatty acid profile: C18:2 cis-9,trans-11 and trans-10,cis-12 isomer (CLA) contents increased by 278 and 233%, respectively, as did eicosapentaenoic acid (C20:5) and docosahexaenoic acid (C22:6) contents. Milk fat fatty acid profile changes were correlated with the modifications in rennet cheese fatty acid profile. Lipid complex supplementation of dairy cows produced considerable changes in the biological value of milk and cheese fat. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  10. The composition-explicit distillation curve technique: Relating chemical analysis and physical properties of complex fluids.

    Science.gov (United States)

    Bruno, Thomas J; Ott, Lisa S; Lovestead, Tara M; Huber, Marcia L

    2010-04-16

    The analysis of complex fluids such as crude oils, fuels, vegetable oils and mixed waste streams poses significant challenges arising primarily from the multiplicity of components, the different properties of the components (polarity, polarizability, etc.) and matrix properties. We have recently introduced an analytical strategy that simplifies many of these analyses, and provides the added potential of linking compositional information with physical property information. This aspect can be used to facilitate equation of state development for the complex fluids. In addition to chemical characterization, the approach provides the ability to calculate thermodynamic properties for such complex heterogeneous streams. The technique is based on the advanced distillation curve (ADC) metrology, which separates a complex fluid by distillation into fractions that are sampled, and for which thermodynamically consistent temperatures are measured at atmospheric pressure. The collected sample fractions can be analyzed by any method that is appropriate. The analytical methods we have applied include gas chromatography (with flame ionization, mass spectrometric and sulfur chemiluminescence detection), thin layer chromatography, FTIR, corrosivity analysis, neutron activation analysis and cold neutron prompt gamma activation analysis. By far, the most widely used analytical technique we have used with the ADC is gas chromatography. This has enabled us to study finished fuels (gasoline, diesel fuels, aviation fuels, rocket propellants), crude oils (including a crude oil made from swine manure) and waste oils streams (used automotive and transformer oils). In this special issue of the Journal of Chromatography, specifically dedicated to extraction technologies, we describe the essential features of the advanced distillation curve metrology as an analytical strategy for complex fluids. Published by Elsevier B.V.

  11. Complexing Agents and pH Influence on Chemical Durability of Type I Molded Glass Containers.

    Science.gov (United States)

    Biavati, Alberto; Poncini, Michele; Ferrarini, Arianna; Favaro, Nicola; Scarpa, Martina; Vallotto, Marta

    2017-01-01

    Among the factors that affect the glass surface chemical durability, pH and complexing agents present in aqueous solution have the main role. Glass surface attack can be also related to the delamination issue causing glass particles' appearance in the pharmaceutical preparation. A few methods to check for glass containers delamination propensity and some control guidelines have been proposed. The present study emphasizes the possible synergy between a few complexing agents with pH on borosilicate glass chemical durability.Hydrolytic attack was performed in small-volume 23 mL type I glass containers autoclaved according to the European Pharmacopoeia or United States Pharmacopeia for 1 h at 121 °C, in order to enhance the chemical attack due to time, temperature, and the unfavorable surface/volume ratio. Solutions of 0.048 M or 0.024 M (M/L) of the acids citric, glutaric, acetic, EDTA (ethylenediaminetetraacetic acid), together with sodium phosphate with water for comparison, were used for the trials. The pH was adjusted ±0.05 units at fixed values 5.5, 6.6, 7, 7.4, 8, and 9 by LiOH diluted solution.Because silicon is the main glass network former, silicon release into the attack solutions was chosen as the main index of the glass surface attack and analysed by inductively coupled plasma atomic emission spectrophotometry. The work was completed by the analysis of the silicon release in the worst attack conditions of molded glass, soda lime type II glass, and tubing borosilicate glass vials to compare different glass compositions and forming technologies. Surface analysis by scanning electron microscopy was finally performed to check for the surface status after the worst chemical attack condition by citric acid.LAY ABSTRACT: Glass, like every packaging material, can have some usage limits, mainly in basic pH solutions. The issue of glass surface degradation particles that appear in vials (delamination) has forced a number of drug product recalls in recent years. To

  12. Characterization of citrate capped gold nanoparticle-quercetin complex: Experimental and quantum chemical approach

    Science.gov (United States)

    Pal, Rajat; Panigrahi, Swati; Bhattacharyya, Dhananjay; Chakraborti, Abhay Sankar

    2013-08-01

    Quercetin and several other bioflavonoids possess antioxidant property. These biomolecules can reduce the diabetic complications, but metabolize very easily in the body. Nanoparticle-mediated delivery of a flavonoid may further increase its efficacy. Gold nanoparticle is used by different groups as vehicle for drug delivery, as it is least toxic to human body. Prior to search for the enhanced efficacy, the gold nanoparticle-flavonoid complex should be prepared and well characterized. In this article, we report the interaction of gold nanoparticle with quercetin. The interaction is confirmed by different biophysical techniques, such as Scanning Electron Microscope (SEM), Circular Dichroism (CD), Fourier-Transform InfraRed (FT-IR) spectroscopy and Thermal Gravimetric Analysis (TGA) and cross checked by quantum chemical calculations. These studies indicate that gold clusters are covered by citrate groups, which are hydrogen bonded to the quercetin molecules in the complex. We have also provided evidences how capping is important in stabilizing the gold nanoparticle and further enhances its interaction with other molecules, such as drugs. Our finding also suggests that gold nanoparticle-quercetin complex can pass through the membranes of human red blood cells.

  13. Atmospheric pressure chemical ionization Fourier transform ion cyclotron resonance mass spectrometry for complex thiophenic mixture analysis

    KAUST Repository

    Hourani, Nadim

    2013-10-01

    Rationale Polycyclic aromatic sulfur heterocycles (PASHs) are detrimental species for refining processes in petroleum industry. Current mass spectrometric Methods that determine their composition are often preceded by derivatization and dopant addition approaches. Different ionization Methods have different impact on the molecular assignment of complex PASHs. The analysis of such species under atmospheric pressure chemical ionization (APCI) is still considered limited due to uncontrolled ion generation with low- and high-mass PASHs. Methods The ionization behavior of a model mixture of five selected PASH standards was investigated using an APCI source with nitrogen as the reagent gas. A complex thiophenic fraction was separated from a vacuum gas oil (VGO) and injected using the same method. The samples were analyzed using Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS). RESULTS PASH model analytes were successfully ionized and mainly [M + H]+ ions were produced. The same ionization pattern was observed for the real thiophenic sample. It was found that S1 class species were the major sulfur-containing species found in the VGO sample. These species indicated the presence of alkylated benzothiophenic (BT), dibenzothiophenic (DBT) and benzonaphthothiophenic (BNT) series that were detected by APCI-FTICR MS. CONCLUSIONS This study provides an established APCI-FTICR MS method for the analysis of complex PASHs. PASHs were detected without using any derivatization and without fragmentation. The method can be used for the analysis of S-containing crude oil samples. © 2013 John Wiley & Sons, Ltd.

  14. Moving to business – changes in physical activity and sedentary behavior after multilevel intervention in small and medium-size workplaces

    Directory of Open Access Journals (Sweden)

    Minna Aittasalo

    2017-04-01

    Full Text Available Abstract Background Regular physical activity (PA promotes and excessive sedentary behavior (SB deteriorates health. Yet the Finnish working-aged population spends most of the day sitting. A 1-year Moving To Business (MTB -intervention supported small and medium-size workplaces to combat sedentariness. This paper reports the changes in employees’ PA and SB from before MTB (baseline to 1 year after baseline (follow-up. Methods Twelve workplaces with a total of 396 employees participated. Each workplace nominated a team to promote PA and reduce SB at organizational, working unit and employee level. The teams were mentored regionally through meetings, workshop and tools. Changes in PA and SB were assessed with a questionnaire and an accelerometer. Wald Confidence Interval (Cl for a difference of proportions with matched pairs was used in the questionnaire data (%-points with 95% CI and linear mixed model in the accelerometer data (minutes and % of wear-time with 95% CI. Results The mean age of the respondents to the questionnaire (N = 296; 75% was 42.6 (SD 10.9, 64% were women, 95% had some education after high school, 74% worked in the day shift, 71% did sedentary work and 51% were overweight. The mean number of actions implemented in the workplaces was 6.8 and the multilevel approach was fully applied in 6 workplaces. Based on the questionnaire the time spent in SB decreased from baseline to follow-up 16% (95% CI −29 to −3 in total and 22% (−41 to −3 at work. The accelerometer showed daily increases of 33.7 min (15.3 to 52.1 and 6.8% (3.1 to 10.4 in total PA, 30.9 min (15.3 to 46.5 and 6.1% (2.9 to 9.2 in light PA and 673 (209 to 1139 more steps at work. Daily SB at work decreased 44.9 min (−68.0 to −21.8 and 7.6% (−11.9 to −3.2. Daily leisure PA declined 11.0 min (−24.9 to 2.9 and 3.2% (−6.2 to −0.2. Number of levels or actions had no effect on changes. Conclusions Employees’ PA increased and SB reduced at work

  15. Characterization of Protein Complexes Using Chemical Cross-Linking Coupled Electrospray Mass Spectrometry.

    Science.gov (United States)

    Cummins, Timothy D; Sapkota, Gopal P

    2017-10-25

    Identification and characterization of large protein complexes is a mainstay of biochemical toolboxes. Utilization of cross-linking chemicals can facilitate the capture and identification of transient or weak interactions of a transient nature (Huang and Kim, PloS One 8:e61430, 2013; Gao et al., J Vis Exp doi: 10.3791/51387, 2014). Here we describe a detailed methodology for a cell culture-based proteomic approach. We describe the generation of cells stably expressing green fluorescent protein (GFP)-tagged proteins under the tetracycline-inducible promoter and subsequent proteomic analysis of GFP-interacting proteins. We include a list of proteins that were identified as interactors of GFP.

  16. Hyperplane distance neighbor clustering based on local discriminant analysis for complex chemical processes monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Chunhong; Xiao, Shaoqing; Gu, Xiaofeng [Jiangnan University, Wuxi (China)

    2014-11-15

    The collected training data often include both normal and faulty samples for complex chemical processes. However, some monitoring methods, such as partial least squares (PLS), principal component analysis (PCA), independent component analysis (ICA) and Fisher discriminant analysis (FDA), require fault-free data to build the normal operation model. These techniques are applicable after the preliminary step of data clustering is applied. We here propose a novel hyperplane distance neighbor clustering (HDNC) based on the local discriminant analysis (LDA) for chemical process monitoring. First, faulty samples are separated from normal ones using the HDNC method. Then, the optimal subspace for fault detection and classification can be obtained using the LDA approach. The proposed method takes the multimodality within the faulty data into account, and thus improves the capability of process monitoring significantly. The HDNC-LDA monitoring approach is applied to two simulation processes and then compared with the conventional FDA based on the K-nearest neighbor (KNN-FDA) method. The results obtained in two different scenarios demonstrate the superiority of the HDNC-LDA approach in terms of fault detection and classification accuracy.

  17. Chemical Control for Host-Parasitoid Model within the Parasitism Season and Its Complex Dynamics

    Directory of Open Access Journals (Sweden)

    Tao Wang

    2016-01-01

    Full Text Available In the present paper, we develop a host-parasitoid model with Holling type II functional response function and chemical control, which can be applied at any time of each parasitism season or pest generation, and focus on addressing the importance of the timing of application pesticide during the parasitism season or pest generation in successful pest control. Firstly, the existence and stability of both the host and parasitoid populations extinction equilibrium and parasitoid-free equilibrium have been investigated. Secondly, the effects of key parameters on the threshold conditions have been discussed in more detail, which shows the importance of pesticide application times on the pest control. Thirdly, the complex dynamics including multiple attractors coexistence, chaotic behavior, and initial sensitivity have been studied by using numerical bifurcation analyses. Finally, the uncertainty and sensitivity of all the parameters on the solutions of both the host and parasitoid populations are investigated, which can help us to determine the key parameters in designing the pest control strategy. The present research can help us to further understand the importance of timings of pesticide application in the pest control and to improve the classical chemical control and to make management decisions.

  18. The Influence of Management's Work-Life Balance on the Organizational Behavior of Employees in Small and Medium-sized Enterprises : Empirical Analysis Focusing on Spillover and Crossover Effects

    OpenAIRE

    平野, 光俊; 余合, 淳

    2017-01-01

    This study investigates the crossover effect of work-life balance (WLB) in the relationship between the management of small and medium-sized enterprises (SMEs) and their employees. SMEs are smaller in scale and have fewer employees than large enterprises, resulting in a close relationship between management and employees. In SMEs, it is easier for employees to observe the daily behavior of the management. Therefore, if management's WLB satisfaction is high, the positive attitude of the manage...

  19. System sight at a problem of efficiency of enterprises’s operaton of the Russian chemical complex

    Directory of Open Access Journals (Sweden)

    Svyatoslav Arkadyevich Nikitin

    2011-06-01

    Full Text Available Chemical industry plays an important role in the development of the domestic economy as one of the basic facilities of Russia's economy, laying the foundation for its long-term and stable development. As a major supplier of raw materials, intermediates, and products of various materials (plastics, chemical fibers, tires, paints and varnishes, dyes, fertilizers, feed additives, pharmaceuticals, medical equipment etc. in almost all sectors of industry, agriculture, health care, human services, commerce, science, culture and education, defense industry, chemical complex has direct impact on the efficiency of their operation and development in these new directions. Therefore, the condition and development of domestic chemistry determines the level of national competitiveness, economic growth and Russia's wealth. However, like most industries in Russia today, chemical industry is going through a difficult period. The presence of a set of common economic problems (identified by technological backwardness and high depreciation, low innovation activity of domestic enterprises of the chemical complex, a lack of effectiveness of the investment process, infrastructure and resource constraints etc., as well as internal management problems causes the rapid growth of interest of uncompetitive Russian chemical products on the world market. Under these conditions, not only a radical adjustment of the internal control systems and chemical plants, but also a significant organizational and economic change is required. Thus, unless we take measures to improve the domestic chemical industry in the coming years, almost all of it grow back and may get into the situation of struggle for survival.

  20. The chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functions

    Science.gov (United States)

    Garnham, Christopher P.; Roll-Mecak, Antonina

    2012-01-01

    Cellular microtubules are marked by abundant and evolutionarily conserved post-translational modifications that have the potential to tune their functions. This review focuses on the astonishing chemical complexity introduced in the tubulin heterodimer at the post-translational level and summarizes the recent advances in identifying the enzymes responsible for these modifications and deciphering the consequences of tubulin’s chemical diversity on the function of molecular motors and microtubule associated proteins. PMID:22422711

  1. A Chemical Composition Survey of the Iron-complex Globular Cluster NGC 6273 (M19)

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Christian I.; Caldwell, Nelson [Harvard–Smithsonian Center for Astrophysics, 60 Garden Street, MS-15, Cambridge, MA 02138 (United States); Rich, R. Michael [Department of Physics and Astronomy, UCLA, 430 Portola Plaza, Box 951547, Los Angeles, CA 90095-1547 (United States); Mateo, Mario [Department of Astronomy, University of Michigan, Ann Arbor, MI 48109 (United States); Bailey, John I. III [Leiden Observatory, Leiden University, P.O. Box 9513, 2300RA Leiden (Netherlands); Clarkson, William I. [Department of Natural Sciences, University of Michigan–Dearborn, 4901 Evergreen Road, Dearborn, MI 48128 (United States); Olszewski, Edward W. [Steward Observatory, The University of Arizona, 933 N. Cherry Avenue, Tucson, AZ 85721 (United States); Walker, Matthew G., E-mail: cjohnson@cfa.harvard.edu, E-mail: ncaldwell@cfa.harvard.edu, E-mail: rmr@astro.ucla.edu, E-mail: mmateo@umich.edu, E-mail: baileyji@strw.leidenuniv.nl, E-mail: wiclarks@umich.edu, E-mail: eolszewski@as.arizona.edu, E-mail: mgwalker@andrew.cmu.edu [McWilliams Center for Cosmology, Department of Physics, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213 (United States)

    2017-02-20

    Recent observations have shown that a growing number of the most massive Galactic globular clusters contain multiple populations of stars with different [Fe/H] and neutron-capture element abundances. NGC 6273 has only recently been recognized as a member of this “iron-complex” cluster class, and we provide here a chemical and kinematic analysis of >300 red giant branch and asymptotic giant branch member stars using high-resolution spectra obtained with the Magellan –M2FS and VLT–FLAMES instruments. Multiple lines of evidence indicate that NGC 6273 possesses an intrinsic metallicity spread that ranges from about [Fe/H] = −2 to −1 dex, and may include at least three populations with different [Fe/H] values. The three populations identified here contain separate first (Na/Al-poor) and second (Na/Al-rich) generation stars, but a Mg–Al anti-correlation may only be present in stars with [Fe/H] ≳ −1.65. The strong correlation between [La/Eu] and [Fe/H] suggests that the s-process must have dominated the heavy element enrichment at higher metallicities. A small group of stars with low [ α /Fe] is identified and may have been accreted from a former surrounding field star population. The cluster’s large abundance variations are coupled with a complex, extended, and multimodal blue horizontal branch (HB). The HB morphology and chemical abundances suggest that NGC 6273 may have an origin that is similar to ω Cen and M54.

  2. Characterisation of the chemical profiles of Brazilian and Andean morphotypes belonging to the Anastrepha fraterculus complex (Diptera, Tephritidae).

    Science.gov (United States)

    Vaníčková, Lucie; Břízová, Radka; Pompeiano, Antonio; Ferreira, Luana Lima; de Aquino, Nathaly Costa; Tavares, Raphael de Farias; Rodriguez, Laura D; Mendonça, Adriana de Lima; Canal, Nelson Augusto; do Nascimento, Ruth Rufino

    2015-01-01

    Fruit fly sexual behaviour is directly influenced by chemical and non-chemical cues that play important roles in reproductive isolation. The chemical profiles of pheromones and cuticular hydrocarbons (CHs) of eight fruit fly populations of the Andean, Brazilian-1 and Brazilian-3 morphotypes of the Anastrepha fraterculus cryptic species complex originating from Colombia (four populations) and Brazil (four populations) were analysed using two-dimensional gas chromatography with mass spectrometric detection. The resulting chemical diversity data were studied using principal component analyses. Andean morphotypes could be discriminated from the Brazilian-1 and Brazilian-3 morphotypes by means of male-borne pheromones and/or male and female CH profiles. The Brazilian-1 and Brazilian-3 morphotypes were found to be monophyletic. The use of chemical profiles as species- and sex-specific signatures for cryptic species separations is discussed.

  3. Opiates Modulate Noxious Chemical Nociception through a Complex Monoaminergic/Peptidergic Cascade.

    Science.gov (United States)

    Mills, Holly; Ortega, Amanda; Law, Wenjing; Hapiak, Vera; Summers, Philip; Clark, Tobias; Komuniecki, Richard

    2016-05-18

    The ability to detect noxious stimuli, process the nociceptive signal, and elicit an appropriate behavioral response is essential for survival. In Caenorhabditis elegans, opioid receptor agonists, such as morphine, mimic serotonin, and suppress the overall withdrawal from noxious stimuli through a pathway requiring the opioid-like receptor, NPR-17. This serotonin- or morphine-dependent modulation can be rescued in npr-17-null animals by the expression of npr-17 or a human κ opioid receptor in the two ASI sensory neurons, with ASI opioid signaling selectively inhibiting ASI neuropeptide release. Serotonergic modulation requires peptides encoded by both nlp-3 and nlp-24, and either nlp-3 or nlp-24 overexpression mimics morphine and suppresses withdrawal. Peptides encoded by nlp-3 act differentially, with only NLP-3.3 mimicking morphine, whereas other nlp-3 peptides antagonize NLP-3.3 modulation. Together, these results demonstrate that opiates modulate nociception in Caenorhabditis elegans through a complex monoaminergic/peptidergic cascade, and suggest that this model may be useful for dissecting opiate signaling in mammals. Opiates are used extensively to treat chronic pain. In Caenorhabditis elegans, opioid receptor agonists suppress the overall withdrawal from noxious chemical stimuli through a pathway requiring an opioid-like receptor and two distinct neuropeptide-encoding genes, with individual peptides from the same gene functioning antagonistically to modulate nociception. Endogenous opioid signaling functions as part of a complex, monoaminergic/peptidergic signaling cascade and appears to selectively inhibit neuropeptide release, mediated by a α-adrenergic-like receptor, from two sensory neurons. Importantly, receptor null animals can be rescued by the expression of the human κ opioid receptor, and injection of human opioid receptor ligands mimics exogenous opiates, highlighting the utility of this model for dissecting opiate signaling in mammals

  4. Computational modelling of the complex dynamics of chemically blown polyurethane foam

    Science.gov (United States)

    Ireka, I. E.; Niedziela, D.; Schäfer, K.; Tröltzsch, J.; Steiner, K.; Helbig, F.; Chinyoka, T.; Kroll, L.

    2015-11-01

    This study presents computational analysis of the complex dynamics observed in chemically blown polyurethane foams during reaction injection molding process. The mathematical formulation introduces an experimentally motivated non-divergence free setup for the continuity equations which reflects the self expanding behaviour observed in the physical system. The foam growth phenomena which is normally initiated by adequate pre-mixing of necessary reactant polymers, leading to an exothermic polymerization reaction, bubble nucleation, and gas formation, is captured numerically. We assume the dependence of material viscosity on the degree of cure/polymerization, gas volume fraction, and temperature as well as non-dependence of mixture density on pressure. The set of unsteady nonlinear coupled partial differential equations describing the dynamics of the system are solved numerically for state variables using finite volume techniques such that the front of the flow is tracked with high resolution interface capturing schemes. Graphical representation of the foam volume fraction, evolution of foam heights, and temperature distributions is presented. Results from our simulations are validated with experimental data. These results show good quantitative agreement with observations from experiments.

  5. Complex bud architecture and cell-specific chemical patterns enable supercooling of Picea abies bud primordia.

    Science.gov (United States)

    Kuprian, Edith; Munkler, Caspar; Resnyak, Anna; Zimmermann, Sonja; Tuong, Tan D; Gierlinger, Notburga; Müller, Thomas; Livingston, David P; Neuner, Gilbert

    2017-12-01

    Bud primordia of Picea abies, despite a frozen shoot, stay ice free down to -50 °C by a mechanism termed supercooling whose biophysical and biochemical requirements are poorly understood. Bud architecture was assessed by 3D-reconstruction, supercooling and freezing patterns by infrared video thermography, freeze dehydration and extraorgan freezing by water potential measurements, and cell-specific chemical patterns by Raman microscopy and mass spectrometry imaging. A bowl-like ice barrier tissue insulates primordia from entrance by intrinsic ice. Water repellent and densely packed bud scales prevent extrinsic ice penetration. At -18 °C, break-down of supercooling was triggered by intrinsic ice nucleators whereas the ice barrier remained active. Temperature-dependent freeze dehydration (-0.1 MPa K-1 ) caused accumulation of extraorgan ice masses that by rupture of the shoot, pith tissue are accommodated in large voids. The barrier tissue has exceptionally pectin-rich cell walls and intercellular spaces, and the cell lumina were lined or filled with proteins, especially near the primordium. Primordial cells close to the barrier accumulate di, tri and tetrasaccharides. Bud architecture efficiently prevents ice penetration, but ice nucleators become active inside the primordium below a temperature threshold. Biochemical patterns indicate a complex cellular interplay enabling supercooling and the necessity for cell-specific biochemical analysis. © 2017 The Authors Plant, Cell & Environment Published by John Wiley & Sons Ltd.

  6. Intraparticulate Metal Speciation Analysis of Soft Complexing Nanoparticles. The Intrinsic Chemical Heterogeneity of Metal-Humic Acid Complexes.

    Science.gov (United States)

    Town, Raewyn M; van Leeuwen, Herman P

    2016-11-03

    The counterion condensation-Donnan (CCD) model for the electrostatic features of soft, charged nanoparticles (NPs) is applied to the determination of the intrinsic stability constants, K̅int, for inner-sphere Cd(II) and Cu(II) complexes with humic acid NPs. The novel CCD model accounts for the strong ion condensation potential for higher valency counterions within the intraparticulate double layer zone of the soft NP. The approach offers new insights into the intrinsic heterogeneity of the HA complexes, as revealed by the intraparticulate speciation as a function of the true degree of inner-sphere complexation, θM. The ensuing intrinsic heterogeneity parameters, Γ, for CdHA and CuHA complexes are in very good agreement with those obtained from dynamic electrochemical stripping chronopotentiometric measurements. The overall intraparticulate metal ion speciation is found to depend on θM: at low θM the strong inner-sphere complexes predominate whereas at higher θM values, electrically condensed M may be an equally significant or even larger fraction of the particle-associated M.

  7. Application of the threshold of toxicological concern (TTC) concept to the safety assessment of chemically complex food matrices

    NARCIS (Netherlands)

    Rennen, M.A.J.; Koster, S.; Krul, C.A.M.; Houben, G.F.

    2011-01-01

    The toxicological assessment of chemically complex food matrices (CCFM) usually is very time consuming, expensive and uses many animal studies. Improvements to obtain a more efficient assessment process remain limited as long as we retain traditional approaches to toxicological risk assessment. New

  8. Chemical Hydrogen Storage Using Polyhedral Borane Anions and Aluminum-Ammonia-Borane Complexes

    Energy Technology Data Exchange (ETDEWEB)

    Hawthorne, M. Frederick; Jalisatgi, Satish S.; Safronov, Alexander V.; Lee, Han Beak; Wu, Jianguo

    2010-10-01

    Phase 1. Hydrolysis of borohydride compounds offer the potential for significant hydrogen storage capacity, but most work to date has focused on one particular anion, BH4-, which requires high pH for stability. Other borohydride compounds, in particular polyhedral borane anions offer comparable hydrogen storage capacity without requiring high pH media and their long term thermal and hydrolytic stability coupled with non-toxic nature make them a very attractive alternative to NaBH4. The University of Missouri project provided the overall program focal point for the investigation of catalytic hydrolysis of polyhedral borane anions for hydrogen release. Due to their inherent stability, a transition metal catalyst was necessary for the hydrolysis of polyhedral borane anions. Transition metal ions such as cobalt, nickel, palladium and rhodium were investigated for their catalytic activity in the hydrolysis of nido-KB11H14, closo-K2B10H10, and closo-K2B12H12. The rate of hydrolysis follows first-order kinetics with respect to the concentration of the polyhedral borane anion and surface area of the rhodium catalyst. The rate of hydrolysis depends upon a) choice of polyhedral borane anion, c) concentration of polyhedral borane anion, d) surface area of the rhodium catalyst and e) temperature of the reaction. In all cases the yield of hydrogen was 100% which corresponds to ~7 wt% of hydrogen (based on material wt%). Phase 2. The phase 2 of program at the University of Missouri was focused upon developing aluminum ammonia-boranes (Al-AB) as chemical hydrogen storage materials, specifically their synthesis and studies of their dehydrogenation. The ammonia borane molecule (AB) is a demonstrated source of chemically stored hydrogen (19.6 wt%) which meets DOE performance parameters except for its regeneration from spent AB and elemental hydrogen. The presence of an aluminum center bonded to multiple AB residues might combine the efficiency of AB dehydrogenation with an aluminum

  9. Towards a Systemic Model of Knowledge Interaction. A Study in the Context of High-Tech Small and Medium Sized Firms

    NARCIS (Netherlands)

    Kraaijenbrink, Jeroen

    2006-01-01

    In this study, knowledge integration (KI) is all the activities by which an organization identifies, acquires, and utilizes external knowledge. While crucial for organizations that develop new products, KI is a complex process that is not well understood in both research and practice. In research,

  10. Light interception efficiency explained by two simple variables: a test using a diversity of small- to medium-sized woody plants

    NARCIS (Netherlands)

    Duursma, R.A.; Falster, D.S.; Valladares, F.; Sterck, F.J.; Pearcy, R.W.; Lusk, C.; Sendall, K.M.; Nordenstahl, M.; Houter, N.C.; Atwell, B.J.; Kelly, N.; Kelly, J.W.G.; Liberloo, M.; Tissue, D.T.; Medlyn, B.E.; Ellsworth, D.S.

    2012-01-01

    Plant light interception efficiency is a crucial determinant of carbon uptake by individual plants and by vegetation. Our aim was to identify whole-plant variables that summarize complex crown architecture, which can be used to predict light interception efficiency. •We gathered the largest database

  11. CHEMICALS

    CERN Multimedia

    Medical Service

    2002-01-01

    It is reminded that all persons who use chemicals must inform CERN's Chemistry Service (TIS-GS-GC) and the CERN Medical Service (TIS-ME). Information concerning their toxicity or other hazards as well as the necessary individual and collective protection measures will be provided by these two services. Users must be in possession of a material safety data sheet (MSDS) for each chemical used. These can be obtained by one of several means : the manufacturer of the chemical (legally obliged to supply an MSDS for each chemical delivered) ; CERN's Chemistry Service of the General Safety Group of TIS ; for chemicals and gases available in the CERN Stores the MSDS has been made available via EDH either in pdf format or else via a link to the supplier's web site. Training courses in chemical safety are available for registration via HR-TD. CERN Medical Service : TIS-ME :73186 or service.medical@cern.ch Chemistry Service : TIS-GS-GC : 78546

  12. Chemical Complexity in the Eu-enhanced Monometallic Globular NGC 5986

    Science.gov (United States)

    Johnson, Christian I.; Caldwell, Nelson; Rich, R. Michael; Mateo, Mario; Bailey, John I., III; Olszewski, Edward W.; Walker, Matthew G.

    2017-06-01

    NGC 5986 is a poorly studied but relatively massive Galactic globular cluster that shares several physical and morphological characteristics with “iron-complex” clusters known to exhibit significant metallicity and heavy-element dispersions. In order to determine whether NGC 5986 joins the iron-complex cluster class, we investigated the chemical composition of 25 red giant branch and asymptotic giant branch cluster stars using high-resolution spectra obtained with the Magellan-M2FS instrument. Cluster membership was verified using a combination of radial velocity and [Fe/H] measurements, and we found the cluster to have a mean heliocentric radial velocity of +99.76 km s-1 (σ = 7.44 km s-1). We derived a mean metallicity of [Fe/H] = -1.54 dex (σ = 0.08 dex), but the cluster’s small dispersion in [Fe/H] and low [La/Eu] abundance preclude it from being an iron-complex cluster. NGC 5986 has =+0.76 {dex} (σ = 0.08 dex), which is among the highest ratios detected in a Galactic cluster, but the small [Eu/Fe] dispersion is puzzling because such high values near [Fe/H] ˜ -1.5 are typically only found in dwarf galaxies exhibiting large [Eu/Fe] variations. NGC 5986 exhibits classical globular cluster characteristics, such as uniformly enhanced [α/Fe] ratios, a small dispersion in Fe-peak abundances, and (anti)correlated light-element variations. Similar to NGC 2808, we find evidence that NGC 5986 may host at least four to five populations with distinct light-element compositions, and the presence of a clear Mg-Al anticorrelation along with an Al-Si correlation suggests that the cluster gas experienced processing at temperatures ≳65-70 MK. However, the current data do not support burning temperatures exceeding ˜100 MK. We find some evidence that the first- and second-generation stars in NGC 5986 may be fully spatially mixed, which could indicate that the cluster has lost a significant fraction of its original mass. This paper includes data gathered with the 6.5 m

  13. Quantum chemical analysis of Со2+ aqua complexes electrochemical reduction

    Directory of Open Access Journals (Sweden)

    Viktor F. Vargalyuk

    2017-11-01

    Full Text Available Based on the analysis of quantum chemical calculations results (GAMESS, density functional theory, B3LYP method as to [Co(H2On]z(H2O6–n clusters for z = 0, 1, 2 and n=1÷6, it has been demonstrated that electrochemical reduction of [Co(H2O6]2+ aqua complexes runs stage-wise. At the first stage, an electron injected into the [Co(H2O6]2+ complex is entirely located in the orbital of the central atom, as z(Co herewith changes from +1.714 е to +0.777 е. The weakening of Со–ОН2 bonds leads to decomposition of resulting [Co(H2O6]+ particles into two energetically related forms – [Co(H2O4]+ and [Co(H2O3]+. Further reduction of these intermediates runs differently. Electron injection into the [Co(H2O3]+ intermediate terminatesthe transition of Со2+-ions to Со0 z(Co= –0.264 е. This process is accompanied by rapid decomposition of [Co(H2O3]0 product into monohydrate atom of cobalt Со(Н2О. On the contrary, electron injection into the [Co(H2O4]+ intermediate leads to emergence of a specific structure – [Co+(H2O–(Н2О3]¹0, whereby the electron is located in the atoms of cobalt only by 28%, and by 72% in cobalt-coordinated water molecules, clearly focusing on one of the. In this molecule, z(H2O changes from +0.148 е to –0.347 е. There is an assumption that a non-equilibrium [Co+(H2O–(Н2О3]0¹ form transits to [Co(ОH(Н2О3]0 hydroxo-form, which further disproportionates turning into Co(ОH2 hydroxide. In order to reduce the impact of this unfavorable reaction pathway on the overall reaction rate Со2+ + 2ē = Со0, we suggest raising the temperature to ensure complete dissociation of [Co(H2O4]+ to [Co(H2O3]+.

  14. Systematic reduction of complex tropospheric chemical mechanisms, Part I: sensitivity and time-scale analyses

    Directory of Open Access Journals (Sweden)

    L. E. Whitehouse

    2004-01-01

    Full Text Available Explicit mechanisms describing the complex degradation pathways of atmospheric volatile organic compounds (VOCs are important, since they allow the study of the contribution of individual VOCS to secondary pollutant formation. They are computationally expensive to solve however, since they contain large numbers of species and a wide range of time-scales causing stiffness in the resulting equation systems. This paper and the following companion paper describe the application of systematic and automated methods for reducing such complex mechanisms, whilst maintaining the accuracy of the model with respect to important species and features. The methods are demonstrated via application to version 2 of the Leeds Master Chemical Mechanism. The methods of Jacobian analysis and overall rate sensitivity analysis proved to be efficient and capable of removing the majority of redundant reactions and species in the scheme across a wide range of conditions relevant to the polluted troposphere. The application of principal component analysis of the rate sensitivity matrix was computationally expensive due to its use of the decomposition of very large matrices, and did not produce significant reduction over and above the other sensitivity methods. The use of the quasi-steady state approximation (QSSA proved to be an extremely successful method of removing the fast time-scales within the system, as demonstrated by a local perturbation analysis at each stage of reduction. QSSA species were automatically selected via the calculation of instantaneous QSSA errors based on user-selected tolerances. The application of the QSSA led to the removal of a large number of alkoxy radicals and excited Criegee bi-radicals via reaction lumping. The resulting reduced mechanism was shown to reproduce the concentration profiles of the important species selected from the full mechanism over a wide range of conditions, including those outside of which the reduced mechanism was

  15. Intraparticulate Metal Speciation Analysis of Soft Complexing Nanoparticles. The Intrinsic Chemical Heterogeneity of Metal-Humic Acid Complexes

    DEFF Research Database (Denmark)

    Town, R. M.; van Leeuwen, Herman P.

    2016-01-01

    The counterion condensation-Dorman (CCD) model for the electrostatic features of soft, charged nanopartides (NPs) is applied to the determination of the intrinsic stability constants, kit, for inner-sphere Cd(II) and Cu(II) complexes with humic acid NPs. The novel CCD model accounts for the strong...

  16. THE INFLUENCE OF THE COMPLEX CHEMICAL ADDITIVE CONTAINING THE STRUCTURED CARBON NANOMATERIAL ON PROPERTIES OF CEMENT

    Directory of Open Access Journals (Sweden)

    O. Yu. Sheyda

    2015-01-01

    Full Text Available The paper presents results of investigations on influence of domestic complex chemical additive containing structured carbon nanomaterial and characterized by a combination effect (curing acceleration and plasticizing on cement and cement stone properties. The purpose of the investigations, on the one hand, has been to confirm efficacy of УКД-1additive from the perspective for increasing the rate of gain, strength growth of cement concrete and additive influence on setting time with the purpose to preserve molding properties of concrete mixes in time, and on the other hand, that is to assess “mechanism” of the УКД-1 additive action in the cement concrete. The research results have revealed regularities in changes due to the additive of water requirements and time period of the cement setting. The reqularities are considered as a pre-requisite for relevant changes in molding properties of the concrete mixes. The paper also experimentally substantiates the possibility to decrease temperature of cement concrete heating with the УДК-1 additive. It has been done with the purpose to save energy resources under production conditions. In addition to this the paper proves the efficiency of the additive which is expressed in strength increase of cement stone up to 20–40 % in the rated age (28 days that is considered as a basis for strength growth of cement concrete. The paper confirms a hypothesis on physical nature of this phenomenon because the X-ray phase analysis method has shown that there are no changes in morphology of portland cement hydration products under the action of the additive agent containing a structured carbon nanomaterial. Results of theoretical and experimental investigations on УКД-1 additive efficiency have been proved by industrial approbation while fabricating precast concrete products and construction of monolithic structures under plant industrial conditions (Minsk, SS “Stroyprogress” JSC MAPID and on

  17. Study protocol: a cluster randomized controlled trial to assess the effectiveness of a multi-pronged behavioural intervention to improve use of personal protective equipment among migrant workers exposed to organic solvents in small and medium-sized enterprises

    OpenAIRE

    Chen, Wen; Li, Tongyang; Zou, Guanyang; Li, Xudong; Shi, Leiyu; Feng, Shanshan; Shi, Jingrong; Zhou, Fangjing; Han, Siqi; Ling, Li

    2016-01-01

    Background In China, most of migrant workers work in the small and medium-sized enterprises (SMEs) and are a vulnerable group for occupational health. Migrant workers are at increased risk of occupational health risks due to poor occupational health behaviours such as the low use of personal protective equipment (PPE). However, there is a lack of solid evidence regarding how to improve the use of PPE among migrant workers in SMEs. The current study will assess the effectiveness of a multi-pro...

  18. Optimising supermarket promotions of fast moving consumer goods using disaggregated sales data: A case study of Tesco and their small and medium sized suppliers

    OpenAIRE

    Malik, Sheraz Alam

    2015-01-01

    The use of price promotions for fast moving consumer goods (FMCG’s) by supermarkets has increased substantially over the last decade, with significant implications for all stakeholders (suppliers, service providers & retailers) in terms of profitability and waste. The overall impact of price promotions depends on the complex interplay of demand and supply side factors, which has received limited attention in the academic literature. There is anecdotal evidence that in many cases, and particul...

  19. Amphibians and agricultural chemicals: Review of the risks in a complex environment

    Energy Technology Data Exchange (ETDEWEB)

    Mann, Reinier M., E-mail: reinier.mann@uts.edu.a [Centre for Ecotoxicology, Department of Environmental Sciences, University of Technology - Sydney, Sydney, NSW 2006 (Australia); Ecotoxicology and Environmental Contaminants Section, Department of Environment and Climate Change, New South Wales, PO Box 29, Lidcombe, NSW 1825 (Australia); Hyne, Ross V., E-mail: Ross.Hyne@environment.nsw.gov.a [Ecotoxicology and Environmental Contaminants Section, Department of Environment and Climate Change, New South Wales, PO Box 29, Lidcombe, NSW 1825 (Australia); Choung, Catherine B., E-mail: catherine.choung@environment.nsw.gov.a [Department of Biological Sciences and Physical Geography, Macquarie University, NSW 2109 (Australia); Wilson, Scott P., E-mail: s.wilson@cqu.edu.a [Centre for Environmental Management, Central Queensland University, PO Box 1319, Gladstone, QLD 4680 (Australia)

    2009-11-15

    Agricultural landscapes, although often highly altered in nature, provide habitat for many species of amphibian. However, the persistence and health of amphibian populations are likely to be compromised by the escalating use of pesticides and other agricultural chemicals. This review examines some of the issues relating to exposure of amphibian populations to these chemicals and places emphasis on mechanisms of toxicity. Several mechanisms are highlighted, including those that may disrupt thyroid activity, retinoid pathways, and sexual differentiation. Special emphasis is also placed on the various interactions that may occur between different agro-chemicals and between chemicals and other environmental factors. We also examine the indirect effects on amphibian populations that occur when their surrounding pond communities are altered by chemicals. - The literature on the various mechanisms by which amphibians may be affected by agricultural chemicals is reviewed.

  20. Vitimização por violência urbana em uma cidade de médio porte do sul do Brasil Urban violence victimization in a medium size town in south Brazil

    Directory of Open Access Journals (Sweden)

    Suélen Henriques da Cruz

    2011-03-01

    Full Text Available A violência urbana afeta a vida dos indivíduos, tornando-se um problema complexo de saúde e segurança pública. Buscando avaliar a situação de violência em uma cidade de médio porte, realizou-se um estudo transversal, de base populacional, investigando a prevalência de vitimização por violência urbana para furtos, roubos, agressões e furto/roubo à residência nos últimos cinco anos e 12 meses; e o perfil das vítimas e a prevalência de notificação à polícia. Foi construído um escore a fim de medir a vitimização por pelo menos um dos tipos de violência em cada período. Na análise bruta, a associação entre a vitimização por cada tipo de violência e as variáveis independentes foi investigada através do teste de Wald para heterogeneidade e para tendência linear, quando aplicável. A Regressão de Poisson foi utilizada na análise multivariável. Foram entrevistados 2.912 indivíduos (idade > 20 anos, sendo que 16,6% destes sofreram violência no último ano e 28% nos últimos cinco anos. As maiores prevalências de vitimização foram de furto/roubo à residência (9,7% e furto (6,0%. As principais vítimas de violência urbana foram homens e jovens. Mais da metade dos vitimizados não notificou a ocorrência por não confiar na polícia. Os achados confirmam a importância de pesquisas de vitimização além das metrópoles. As discussões sobre o tema mostram a necessidade de incrementar, executar ou criar políticas públicas de segurança e saúde em distintos contextos nacionais, sem desconsiderar cidades do interior.Urban violence affects individuals' lives, and therefore it is a complex problem of public health and security. To evaluate the occurrence of violence in a medium size city, a population-based cross-sectional study was carried out to investigate: prevalence of urban violence victimization (theft, robbery, aggression, and burglary in the period of five years and twelve months before the interview

  1. Evaluating Exposures to Complex Mixtures of Chemicals During a New Production Process in the Plastics Industry

    NARCIS (Netherlands)

    Meijster, T.; Burstyn, I.; Wendel de Joode, van B.; Posthumus, M.A.; Kromhout, H.

    2004-01-01

    The goal of this study was to monitor emission of chemicals at a factory where plastics products were fabricated by a new robotic (impregnated tape winding) production process. Stationary and personal air measurements were taken to determine which chemicals were released and at what concentrations.

  2. Effects of chemical and enzymatic modifications on starch-linoleic acid complex formation.

    Science.gov (United States)

    Arijaje, Emily Oluwaseun; Wang, Ya-Jane

    2017-02-15

    This study investigated the complexation yield and physicochemical properties of soluble and insoluble starch complexes with linoleic acid when a β-amylase treatment was applied to acetylated and debranched potato starch. The degree of acetylation was generally higher in the soluble complexes than in the insoluble ones. The insoluble complexes from the acetylated starch displayed the V-type pattern, whereas, the soluble complexes displayed a mixture of either the A-/V-type or the B-/V-type pattern. Acetylation decreased onset and peak melting temperatures for the insoluble complexes, whereas no melting endotherm was observed in the soluble complexes. Acetylation substantially increased the amount of complexed linoleic acid in the insoluble complexes, but had little positive effect on the formation of the soluble complexes. The β-amylase treatment significantly increased the complexed linoleic content in both soluble and insoluble complexes for the low acetylated starch, but not for the high acetylated starch. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. SPECIES RICHNESS AND INDICES OF ABUNDANCE OF MEDIUM-SIZED MAMMALS IN ANDEAN FOREST AND REFORESTATIONS WITH ANDEAN ALDER: A PRELIMINARY ANALYSIS

    Directory of Open Access Journals (Sweden)

    SÁNCHEZ FRANCISCO

    2008-07-01

    Full Text Available We studied the species richness and two indices of abundance of medium-sizedmammals in areas with Andean forest and Andean alder (Alnus acuminatareforestations in a reserve at the Central Andes of Colombia. Since reforested areashave a less complex habitat structure and lower plant diversity than native forests, wepredicted that they have lower richness of mammals than areas with Andean forest.We obtained the indices of abundance from direct contacts in transects and from theuse of track stations. Our results suggest that, indeed, areas with Andean forest hada higher richness of mammals than reforestations, but this pattern may be modifiedby anthropogenic factors. We found no differences between the indices of abundanceof the squirrel, Sciurus granatensis, in the two forest types. In contrast, the coatiswere recorded more frequently in the reforestations than in areas with Andean forestat the reserve.

  4. Measurements of benzene and formaldehyde in a medium sized urban environment. Indoor/outdoor health risk implications on special population groups.

    Science.gov (United States)

    Pilidis, Georgios A; Karakitsios, Spyros P; Kassomenos, Pavlos A; Kazos, Elias A; Stalikas, Constantine D

    2009-03-01

    In the present study, the results of a measurement campaign aiming to assess cancer risk among two special groups of population: policemen and laboratory technicians exposed to the toxic substances, benzene and formaldehyde are presented. The exposure is compared to general population risk. The results show that policemen working outdoor (traffic regulation, patrol on foot or in vehicles, etc.) are exposed at a significantly higher benzene concentration (3-5 times) than the general population, while the exposure to carbonyls is in general lower. The laboratory technicians appear to be highly exposed to formaldehyde while no significant variation of benzene exposure in comparison to the general population is recorded. The assessment revealed that laboratory technicians and policemen run a 20% and 1% higher cancer risk respectively compared to the general population. Indoor working place air quality is more significant in assessing cancer risk in these two categories of professionals, due to the higher Inhalation Unit Risk (IUR) of formaldehyde compared to benzene. Since the origin of the danger to laboratory technicians is clear (use of chemicals necessary for the experiments), in policemen the presence of carbonyls in indoor air concentrations due to smoking or used materials constitute a danger equal to the exposure to traffic originated air pollutants.

  5. A systems engineering approach to manage the complexity in sustainable chemical product-process design

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    This paper provides a perspective on model-data based solution approaches for chemical product-process design, which consists of finding the identity of the candidate chemical product, designing the process that can sustainably manufacture it and verifying the performance of the product during...... application. The chemical product tree is potentially very large and a wide range of options exist for selecting the product to make, the raw material to use as well as the processing route to employ. It is shown that systematic computer-aided methods and tools integrated within a model-data based design...

  6. Synthesis, physico-chemical characterization and biological activity of 2-aminobenzimidazole complexes with different metal ions

    Directory of Open Access Journals (Sweden)

    Podunavac-Kuzmanović Sanja O.

    2004-01-01

    Full Text Available Complexes of 2-aminobenzimidazole (L with nitrates of cobalt(II nickel(II, copper (II, zinc(II and silver(I were synthesized. The molar ratio metal:ligand in the reaction of the complex formation was 1:2. It should be noticed, that the reaction of all the metal salts yielded bis(ligand complexes of the general formula M(L2(NO32 × nH2O (M=Co, Ni Cu, Zn or Ag; n=0, 1, 2 or 6. The complexes were characterized by elemental analysis of the metal, molar conductivity, magnetic susceptibility measurements and IR spectra. Co(II, Ni(II and Cu(II complexes behave as non-electrolytes, whilst Zn(II and Ag(I are 1:1 electrolytes. Cu(II complex has a square-planar stereochemistry, Ag(I complex is linear, whilst the Co(II, Ni(II and Zn(II complexes have a tetrahedral configuration. In all the complexes ligand is coordinated by participation of the pyridine nitrogen of the benzimidazole ring. The antimicrobial activity of the ligand and its complexes against Pseudomonas aeruginosa, Bacillus sp. Staphylococcus aureus and Saccharomyces cerevisiae was investigated. The effect of metal on the ligand antimicrobial activity is discussed.

  7. Association between chemical pattern in breast milk and congenital cryptorchidism: modelling of complex human exposures

    DEFF Research Database (Denmark)

    Krysiak-Baltyn, Konrad; Toppari, J.; Skakkebaek, N. E.

    2012-01-01

    , polybrominated biphenyls and organochlorine pesticides. Computational analysis of the data was performed using logistic regression and three multivariate machine learning classifiers. Furthermore, we performed systems biology analysis to explore the chemical influence on a molecular level. After correction...

  8. Methodology and tools for improving competence of a chemical plant characterized by a complex Supply Chain network

    OpenAIRE

    LEOFANTI, GUIDO

    2012-01-01

    Supply chain performance is strongly influenced by its design, chosen architecture, logistic network and types of finished product that made their marketplace. Sometimes environmental reasons like site location due to deals between government administration and companies may cause changes in logical design and hence increase logistic network complexity and become in a strategic Supply Chain constraint. Our case study addresses a geographic place of a chemical manufacturing plant inside i...

  9. Light interception efficiency explained by two simple variables: a test using a diversity of small- to medium-sized woody plants.

    Science.gov (United States)

    Duursma, R A; Falster, D S; Valladares, F; Sterck, F J; Pearcy, R W; Lusk, C H; Sendall, K M; Nordenstahl, M; Houter, N C; Atwell, B J; Kelly, N; Kelly, J W G; Liberloo, M; Tissue, D T; Medlyn, B E; Ellsworth, D S

    2012-01-01

    • Plant light interception efficiency is a crucial determinant of carbon uptake by individual plants and by vegetation. Our aim was to identify whole-plant variables that summarize complex crown architecture, which can be used to predict light interception efficiency. • We gathered the largest database of digitized plants to date (1831 plants of 124 species), and estimated a measure of light interception efficiency with a detailed three-dimensional model. Light interception efficiency was defined as the ratio of the hemispherically averaged displayed to total leaf area. A simple model was developed that uses only two variables, crown density (the ratio of leaf area to total crown surface area) and leaf dispersion (a measure of the degree of aggregation of leaves). • The model explained 85% of variation in the observed light interception efficiency across the digitized plants. Both whole-plant variables varied across species, with differences in leaf dispersion related to leaf size. Within species, light interception efficiency decreased with total leaf number. This was a result of changes in leaf dispersion, while crown density remained constant. • These results provide the basis for a more general understanding of the role of plant architecture in determining the efficiency of light harvesting. © 2011 The Authors. New Phytologist © 2011 New Phytologist Trust.

  10. Energy storage system in medium-sized voltage lines for the integration of decentralized fluctuating energy sources; Energiespeicher im Niederspannungsnetz zur Integration dezentraler, fluktuierender Energiequellen

    Energy Technology Data Exchange (ETDEWEB)

    Bodach, M.

    2006-06-30

    The solar radiation fluctuates due to atmospheric and planetary influences. Concerning PV systems, the changes from dark clouds to clear sky result in fast and very deep fluctuations of the time behaviour of the power output fed into the low voltage (LV) network by DC-AC-Converters. On the example of a daily recorded global radiation curve with a very short sampling time (regular interval time 1 s) the paper shows that short-term sags of the solar radiation are possible up to 80% of the previous value as a result of sudden and intensive changes of the density of the clouds. These disturbances of the quality of the generated electric power are directly transformed into the LV grids. If the number of PV systems connected to existing LV networks rises essentially, the fluctuating photovoltaic energy generation will achieve a very high importance and therefore not only the well-known, but also a lot of new problems will occur. They have already been investigated theoretically in different papers and they have also been proven quantitatively by own simulations. Improvements of the energy quality at the point of common coupling will be possible if the grid-coupled PV power plants are supplemented with suitable intelligent storage systems bridging the short-term sags. So the influence of the fluctuating radiation on the generated power can be fundamentally reduced. The developed intelligent short-term storage system smoothes out the generated power of the PV system by means of a storage. It is based on the very high capacity of an electric double layer (UltraCap, produced by EPCOS) and includes a complex electronic control system. The UltraCap has the required storing characteristics and has been adjusted to the system voltage by a highly sophisticated microprocessor controlled DC/DC-converter system. Such an intelligent storage system can also be used for the connection of other decentralised power generation units (e.g. fuel cells, block-unit heating power plant) to the

  11. Chemical and biological evaluation of scandium(III)-polyaminopolycarboxylate complexes as potential PET agents and radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Huclier-Markai, S.; Sabatie, A.; Ribet, S. [Univ. de Nantes (France). Lab. Subatech; Kubicek, V.; Hermann, P. [Charles Univ., Prague (Czech Republic). Dept. of Inorganic Chemistry; Paris, M. [Univ. de Nantes (France). Inst. des Materiaux; Vidaud, C. [CEA/DSV/iBEB/SBTN, Bagnols sur Ceze (France). Lab. d' Etude des Proteines Cibles; Cutler, C.S. [Univ. of Missouri, Columbia, MO (United States). Reserach Reactor Center

    2011-07-01

    Scandium isotopes ({sup 44}Sc, {sup 47}Sc) are more available and their properties are convenient for either PET imaging or radiotherapy. To use them in nuclear medicine, ligands forming complexes with a high stability are necessary. Available experimental data on stability constants for complexes of ligands such as EDTA, DTPA, DOTA, NOTA and TETA with various metal ions have been published. But scandium is the exception since scarce data is available in the literature. Values of stability constants of Sc(III) with the ligands were determined by free-ion selective radiotracer extraction, complemented by {sup 45}Sc NMR and potentiometry data. The thermodynamic stability of the Sc-complexes increases in the order TETA < NOTA < EDTA < DTPA < DOTA. The in vitro stability of the Sc(III) complexes was studied in the presence of hydroxyapatite and rat serum to estimate their in vivo stability. The most stable complex was shown to be Sc-DOTA.

  12. Chemical warfare agent detection in complex environments with comprehensive two-dimensional gas chromatography

    Science.gov (United States)

    Reichenbach, Stephen E.; Ni, Mingtian; Kottapalli, Visweswara; Visvanathan, Arvind; Ledford, Edward B., Jr.; Oostdijk, John; Trap, Henk C.

    2003-08-01

    Comprehensive two-dimensional gas chromatography (GCxGC) is an emerging technology for chemical separation that provides an order-of-magnitude increase in separation capacity over traditional gas chromatography. GCxGC separates chemical species with two capillary columns interfaced by two-stage thermal desorption. Because GCxGC is comprehensive and has high separation capacity, it can perform multiple traditional analytical methods with a single analysis. GCxGC has great potential for a wide variety of environmental sensing applications, including detection of chemical warfare agents (CWA) and other harmful chemicals. This paper demonstrates separation of nerve agents sarin and soman from a matrix of gasoline and diesel fuel. Using a combination of an initial column separating on the basis of boiling point and a second column separating on the basis of polarity, GCxGC clearly separates the nerve agents from the thousands of other chemicals in the sample. The GCxGC data is visualized, processed, and analyzed as a two-dimensional digital image using a software system for GCxGC image processing developed at the University of Nebraska - Lincoln.

  13. Risk assessment for complex chemical exposure in aquatic systems: the problem of estimating interactive effects

    Energy Technology Data Exchange (ETDEWEB)

    Gray, J.S. [Oslo Univ. (Norway). Biological Inst.

    1998-12-31

    The traditional, but little used, way of assessing effects of the interaction between known chemicals is to use factorial experimental designs. Such designs allow one to test for less than additive (antagonistic) and greater than additive (synergistic) effects. Whilst synergism can be demonstrated in such experiments the concentrations at which synergistic effects occur are extremely high and are unlikely to occur in nature. Recently developed techniques allow one to measure directly the effects of combined stressors in the field. These biological effect techniques range from tests on individual organisms to tests on communities. At the biochemical level the tests can indicate that the organism has been exposed to certain groups of chemicals (for example cytochrome P-450 enzymes responding to PAHs or metallothioneins responding to heavy metals). At the community level of organisation there are highly sensitive statistical techniques that indicate clearly the combined effect of stressors. The effects of oil exploration and production on benthic communities in the North Sea can be linked to concentrations of chemicals. However, such relationships are correlative and do not necessarily indicate cause and effect. Experiments are needed to test the hypotheses generated concerning the interactive effects of chemicals on the benthic species. The statistical analyses do, however, show which species have been affected and their relative sensitivity to chemical and physical disturbances. Such species are preferable to the traditional `laboratory weeds` usually utilised. (orig.)

  14. Hydrogen storage in C3Ti complex using quantum chemical methods and molecular dynamics simulations.

    Science.gov (United States)

    Kalamse, Vijayanand; Wadnerkar, Nitin; Chaudhari, Ajay

    2012-06-01

    The hydrogen storage capacity of C(3)Ti and C(3)Ti(+) complex was studied using second order Møller-Plesset (MP2) and density functional theory (DFT) methods with different exchange and correlation functionals. Four and five H(2) molecules can be adsorbed on C(3)Ti and C(3)Ti(+) complex respectively at all the levels of theory used. This corresponds to the gravimetric H(2) uptake capacity of 8.77 and 10.73 wt % for the former and the latter respectively. The nature of interactions between different molecules in H(2) adsorbed complexes is also studied using many-body analysis approach. In the case of C(3)Ti(4H(2)) complex, total five-body interactions is negligible whereas for C(3)Ti(+)(5H(2)) relaxation energy is negligible. All the many-body energies have significant contribution to the binding energy of a respective complex. Atom-centered density matrix propagation molecular dynamics simulations were carried out using different methods to confirm whether H(2) molecules remain adsorbed on C(3)Ti and C(3)Ti(+) complex at room temperature. Adsorption Gibbs free energies show that four and five H(2) molecule adsorption on C(3)Ti and C(3)Ti(+) at room temperature is energetically favorable and unfavorable respectively using MP2 as well as DFT methods used here. H(2) adsorption is thermodynamically favorable over a wide range of temperature on the C(3)Ti than C(3)Ti(+)complex.

  15. Mechanism of Creaming Down Based on Chemical Characterization of a Complex of Caffeine and Tea Catechins.

    Science.gov (United States)

    Ishizu, Takashi; Tsutsumi, Hiroyuki; Sato, Takashi

    2016-01-01

    The component of a precipitate resulting from creaming down, which was made from caffeine and a catechin mixture, was determined by an integrated value of H2 proton signals of tea catechins in the quantitative (1)H-NMR spectrum. The results showed that gallate-type catechins formed a precipitate by creaming down more predominantly than non-gallate-type catechins. X-ray crystallographic analysis showed that the gallate-type catechin (-)-epigallocatechin-3-O-gallate (EGCg), (-)-epicatechin-3-O-gallate (ECg) formed 2 : 2 and 2 : 4 complexes with caffeine, respectively, and the non-gallate-type catechin (-)-epicatechin (EC) and caffeine formed a 1 : 1 complex. The 2 : 2, 2 : 4 complexes of caffeine and EGCg, ECg formed a hydrophobic space with three aromatic A, B, and B' rings of two EGCg, ECg molecules, and one caffeine molecule was captured in this hydrophobic space. However, no such hydrophobic space in the 1 : 1 complex of caffeine and EC formed. It was thought that the hydrophobicity of the 2 : 2, 2 : 4 complexes of caffeine and EGCg, ECg was stronger than that of the 1 : 1 complex of caffeine and EC, with the result that the 2 : 2, 2 : 4 complexes of caffeine and EGCg, ECg precipitated by creaming down more predominantly than the 1 : 1 complex of caffeine and EC in an aqueous solution. Furthermore, the molecular capture of various heterocyclic compounds by formation of the 2 : 2 complex of EGCg from the aqueous solution was investigated using the quantitative (1)H-NMR spectrum.

  16. Directed assembly of functional light harvesting antenna complexes onto chemically patterned surfaces

    NARCIS (Netherlands)

    Escalante Marun, M.; Maury, P.A.; Bruinink, C.M.; van der Werf, Kees; Olsen, John D.; Timney, A.; Huskens, Jurriaan; Hunter, C. Neil; Subramaniam, Vinod; Otto, Cornelis

    2008-01-01

    We report the directed assembly of the photosynthetic membrane proteins LH1 and LH2 isolated from the purple bacterium Rhodobacter sphaeroides onto chemically patterned substrates. Nanoimprint lithography was used to pattern discrete regions of amino- and fluoro-terminated or poly(ethylene glycol)

  17. A guide for the introduction of an integrated management system in small and medium-sized organisations; Leitfaden fuer den Einfuehrungsprozess eines integrierten Managementsystems in kleinen und mittleren Unternehmen

    Energy Technology Data Exchange (ETDEWEB)

    Janas, I.; Mackau, D.; Orban, P. [Technische Hochschule Aachen (Germany). Lehrstuhl und Inst. fuer Arbeitswissenschaft

    2001-07-01

    The authors shows how a process-oriented integrated management system can be introduced in small and medium-sized organisations. The methods described here can also serve the restructuring of an existing management system. [German] Im Zentrum von Reorganisationsmassnahmen steht immer oefter die Einfuehrung integrierter Managementsysteme, welche die Bereiche Qualitaetsmanagement, Umweltschutz sowie Arbeitssicherheit und Gesundheitsschutz abdecken. Bis heute sind in vielen, meist groesseren Unternehmen Managementsysteme entwickelt worden, die als Inselloesungen unabhaenging voneinander bestehen. Die hohen personellen und finanziellen Aufwendungen, die mit parallel betriebenen Systemen einhergehen, erfordern effiziente Integrationskonzepte. Das vorliegende Werk zeigt einen Weg auf, um ein prozessorientiertes integriertes Managementsystem auch in kleinen und mittleren Unternehmen (KMU) einzufuehren. Dieser Leitfaden richtet sich an den betrieblichen Praktiker und soll ihm Hilfestellungen und Anregungen zu Aufbau oder Optimierung eines IMS bieten und die Unternehmen dazu anregen, sich dem TQM-Gedanken zu naehern. Die beschriebenen Methoden koennen darueber hinaus auch eingesetzt werden, um ein bestehendes Managementsystem einer grundlegenden Restrukturierung zu unterziehen. (orig.)

  18. Shift from National Reporting to Reporting in Accordance with International Financial Reporting Standard for Small and Medium-sized Entities and Its Effect on Financial Management – the Case of the Czech Republic

    Directory of Open Access Journals (Sweden)

    Struhařová Kateřina

    2010-12-01

    Full Text Available The aim of this paper is to evaluate the effect of the shift from Financial Reporting under the Czech legislature (CZ GAAP to the International Financial Reporting Standard for financial management in Small and Medium-sized Enterprises (IFRS for SMEs. The reasons for the shift and major differences between CZ GAAP and IFRS for SMEs are mentioned, as well as the changes relevant to the shift. Not only changes in accounting departments are defined but also the changes that affect a company as a whole. Furthermore, information from Financial Reporting used in Financial Management is described. Also, the effect of the changes in Financial Reporting on this information and related modifications affecting Financial Management are evaluated.

  19. Development of ESCO as a tool for realising energy efficiency in small and medium sized industry; ESCO = Energy Service Company; Udvikling af ESCO som vaerktoej til realisering af energieffektivisering i smaa og mellemstore erhvervsvirksomheder

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Ove Folmer (DS Haandvaerk og Industri, Odense (Denmark))

    2011-07-01

    The project carried out an advisory process in 10 different SME (small and medium-sized enterprises). The process was based on energy management and employee involvement in energy conservation activities, which has led to a wide variety of projects in companies that have focused on the initiation and solution of diverse energy-saving activities. Results of the project consist of a series of case studies that describe the processes that have been implemented in the company. The selected cases demonstrate the diversity of businesses, their energy saving potential and need for funding. It also describes and assesses the various financing possibilities, a model for qualitative advising in SMEs and a module for the training of the people involved - including installers, craftsmen and advisor. (LN)

  20. COMPUTATIONAL INVESTIGATION ON THE STRUCTURE AND NMR CHEMICAL SHIFTS OF ENDO-CONE [CS2(p-METHYLCALIX[4]ARENE] COMPLEX

    Directory of Open Access Journals (Sweden)

    Hanggara Sudrajat

    2010-06-01

    Full Text Available The structure and NMR chemical shifts of endo-cone [CS2(p-methylcalix[4]arene] complex have been computationally investigated using BIO+ force fields, semi-empirical (PM3 and ab initio (RHF/6-311G++(d,p calculations. The first comparison of ab initio NMR chemical shift calculations for a calix[4]arene inclusion complex with solid-state 13C NMR chemical shifts based on the 1:1 complex of p-methylcalix[4]arenes with carbon disulfide in endo-cone complexation mode has been reported. The results showed that ab initio (RHF/6-311G++(d,p NMR calculations of the host-guest [CS2(p-methylcalix[4]arene] complex are in good agreement with experimental solid-state NMR data.    Keywords: computational investigation, structure, NMR chemical shifts, [CS2(p-methylcalix[4]arene].