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Sample records for commercial snf accident

  1. Commercial SNF Accident Release Fractions

    Energy Technology Data Exchange (ETDEWEB)

    J. Schulz

    2004-11-05

    The purpose of this analysis is to specify and document the total and respirable fractions for radioactive materials that could be potentially released from an accident at the repository involving commercial spent nuclear fuel (SNF) in a dry environment. The total and respirable release fractions are used to support the preclosure licensing basis for the repository. The total release fraction is defined as the fraction of total commercial SNF assembly inventory, typically expressed as an activity inventory (e.g., curies), of a given radionuclide that is released to the environment from a waste form. Radionuclides are released from the inside of breached fuel rods (or pins) and from the detachment of radioactive material (crud) from the outside surfaces of fuel rods and other components of fuel assemblies. The total release fraction accounts for several mechanisms that tend to retain, retard, or diminish the amount of radionuclides that are available for transport to dose receptors or otherwise can be shown to reduce exposure of receptors to radiological releases. The total release fraction includes a fraction of airborne material that is respirable and could result in inhalation doses; this subset of the total release fraction is referred to as the respirable release fraction. Accidents may involve waste forms characterized as: (1) bare unconfined intact fuel assemblies, (2) confined intact fuel assemblies, or (3) canistered failed commercial SNF. Confined intact commercial SNF assemblies at the repository are contained in shipping casks, canisters, or waste packages. Four categories of failed commercial SNF are identified: (1) mechanically and cladding-penetration damaged commercial SNF, (2) consolidated/reconstituted assemblies, (3) fuel rods, pieces, and debris, and (4) nonfuel components. It is assumed that failed commercial SNF is placed into waste packages with a mesh screen at each end (CRWMS M&O 1999). In contrast to bare unconfined fuel assemblies, the

  2. Commercial SNF Accident Release Fractions

    International Nuclear Information System (INIS)

    Schulz, J.

    2004-01-01

    The purpose of this analysis is to specify and document the total and respirable fractions for radioactive materials that could be potentially released from an accident at the repository involving commercial spent nuclear fuel (SNF) in a dry environment. The total and respirable release fractions are used to support the preclosure licensing basis for the repository. The total release fraction is defined as the fraction of total commercial SNF assembly inventory, typically expressed as an activity inventory (e.g., curies), of a given radionuclide that is released to the environment from a waste form. Radionuclides are released from the inside of breached fuel rods (or pins) and from the detachment of radioactive material (crud) from the outside surfaces of fuel rods and other components of fuel assemblies. The total release fraction accounts for several mechanisms that tend to retain, retard, or diminish the amount of radionuclides that are available for transport to dose receptors or otherwise can be shown to reduce exposure of receptors to radiological releases. The total release fraction includes a fraction of airborne material that is respirable and could result in inhalation doses; this subset of the total release fraction is referred to as the respirable release fraction. Accidents may involve waste forms characterized as: (1) bare unconfined intact fuel assemblies, (2) confined intact fuel assemblies, or (3) canistered failed commercial SNF. Confined intact commercial SNF assemblies at the repository are contained in shipping casks, canisters, or waste packages. Four categories of failed commercial SNF are identified: (1) mechanically and cladding-penetration damaged commercial SNF, (2) consolidated/reconstituted assemblies, (3) fuel rods, pieces, and debris, and (4) nonfuel components. It is assumed that failed commercial SNF is placed into waste packages with a mesh screen at each end (CRWMS M andO 1999). In contrast to bare unconfined fuel assemblies, the

  3. COMMERCIAL SNF ACCIDENT RELEASE FRACTIONS

    Energy Technology Data Exchange (ETDEWEB)

    S.O. Bader

    1999-10-18

    The purpose of this design analysis is to specify and document the total and respirable fractions for radioactive materials that are released from an accident event at the Monitored Geologic Repository (MGR) involving commercial spent nuclear fuel (CSNF) in a dry environment. The total and respirable release fractions will be used to support the preclosure licensing basis for the MGR. The total release fraction is defined as the fraction of total CSNF assembly inventory, typically expressed as an activity inventory (e.g., curies), of a given radionuclide that is released to the environment from a waste form. The radionuclides are released from the inside of breached fuel rods (or pins) and from the detachment of radioactive material (crud) from the outside surfaces of fuel rods and other components of fuel assemblies. The total release fraction accounts for several mechanisms that tend to retain, retard, or diminish the amount of radionuclides that are available for transport to dose receptors or otherwise can be shown to reduce exposure of receptors to radiological releases. The total release fraction includes a fraction of airborne material that is respirable and could result in inhalation doses. This subset of the total release fraction is referred to as the respirable release fraction. Potential accidents may involve waste forms that are characterized as either bare (unconfined) fuel assemblies or confined fuel assemblies. The confined CSNF assemblies at the MGR are contained in shipping casks, canisters, or disposal containers (waste packages). In contrast to the bare fuel assemblies, the container that confines the fuel assemblies has the potential of providing an additional barrier for diminishing the total release fraction should the fuel rod cladding breach during an accident. However, this analysis will not take credit for this additional bamer and will establish only the total release fractions for bare unconfined CSNF assemblies, which may however be

  4. COMMERCIAL SNF ACCIDENT RELEASE FRACTIONS

    International Nuclear Information System (INIS)

    S.O. Bader

    1999-01-01

    The purpose of this design analysis is to specify and document the total and respirable fractions for radioactive materials that are released from an accident event at the Monitored Geologic Repository (MGR) involving commercial spent nuclear fuel (CSNF) in a dry environment. The total and respirable release fractions will be used to support the preclosure licensing basis for the MGR. The total release fraction is defined as the fraction of total CSNF assembly inventory, typically expressed as an activity inventory (e.g., curies), of a given radionuclide that is released to the environment from a waste form. The radionuclides are released from the inside of breached fuel rods (or pins) and from the detachment of radioactive material (crud) from the outside surfaces of fuel rods and other components of fuel assemblies. The total release fraction accounts for several mechanisms that tend to retain, retard, or diminish the amount of radionuclides that are available for transport to dose receptors or otherwise can be shown to reduce exposure of receptors to radiological releases. The total release fraction includes a fraction of airborne material that is respirable and could result in inhalation doses. This subset of the total release fraction is referred to as the respirable release fraction. Potential accidents may involve waste forms that are characterized as either bare (unconfined) fuel assemblies or confined fuel assemblies. The confined CSNF assemblies at the MGR are contained in shipping casks, canisters, or disposal containers (waste packages). In contrast to the bare fuel assemblies, the container that confines the fuel assemblies has the potential of providing an additional barrier for diminishing the total release fraction should the fuel rod cladding breach during an accident. However, this analysis will not take credit for this additional bamer and will establish only the total release fractions for bare unconfined CSNF assemblies, which may however be

  5. CONTAINMENT EVALUATION OF BREACHED AL-SNF FOR CASK TRANSPORT

    International Nuclear Information System (INIS)

    Vinson, D. W.; Sindelar, R. L.; Iyer, N. C.

    2005-01-01

    Aluminum-based spent nuclear fuel (Al-SNF) from foreign and domestic research reactors (FRR/DRR) is being shipped to the Savannah River Site. To enter the U.S., the cask with loaded fuel must be certified to comply with the requirements in the Title 10 of the U.S. Code of Federal Regulations, Part 71. The requirements include demonstration of containment of the cask with its contents under normal and accident conditions. Al-SNF is subject to corrosion degradation in water storage, and many of the fuel assemblies are ''failed'' or have through-clad damage. A methodology has been developed with technical bases to show that Al-SNF with cladding breaches can be directly transported in standard casks and maintained within the allowable release rates. The approach to evaluate the limiting allowable leakage rate, L R , for a cask with breached Al-SNF for comparison to its test leakage rate could be extended to other nuclear material systems. The approach for containment analysis of Al-SNF follows calculations for commercial spent fuel as provided in NUREG/CR-6487 that adopts ANSI N14.5 as a methodology for containment analysis. The material-specific features and characteristics of damaged Al-SNF (fuel materials, fabrication techniques, microstructure, radionuclide inventory, and vapor corrosion rates) that were derived from literature sources and/or developed in laboratory testing are applied to generate the four containment source terms that yield four separate cask cavity activity densities; namely, those from fines; gaseous fission product species; volatile fission product species; and fuel assembly crud. The activity values, A 2 , are developed per the guidance of 10CFR71. The analysis is performed parametrically to evaluate maximum number of breached assemblies and exposed fuel area for a proposed shipment in a cask with a test leakage rate

  6. Nevada commercial spent nuclear fuel transportation experience

    International Nuclear Information System (INIS)

    1991-09-01

    The purpose of this report is to present an historic overview of commercial reactor spent nuclear fuel (SNF) shipments that have occurred in the state of Nevada, and to review the accident and incident experience for this type of shipments. Results show that between 1964 and 1990, 309 truck shipments covering approximately 40,000 miles moved through Nevada; this level of activity places Nevada tenth among the states in the number of truck shipments of SNF. For the same period, 15 rail shipments moving through the State covered approximately 6,500 miles, making Nevada 20th among the states in terms of number of rail shipments. None of these shipments had an accident or an incident associated with them. Because the data for Nevada are so limited, national data on SNF transportation and the safety of truck and rail transportation in general were also assessed

  7. SNF fuel retrieval sub project safety analysis document

    International Nuclear Information System (INIS)

    BERGMANN, D.W.

    1999-01-01

    This safety analysis is for the SNF Fuel Retrieval (FRS) Sub Project. The FRS equipment will be added to K West and K East Basins to facilitate retrieval, cleaning and repackaging the spent nuclear fuel into Multi-Canister Overpack baskets. The document includes a hazard evaluation, identifies bounding accidents, documents analyses of the accidents and establishes safety class or safety significant equipment to mitigate accidents as needed

  8. SNF fuel retrieval sub project safety analysis document

    Energy Technology Data Exchange (ETDEWEB)

    BERGMANN, D.W.

    1999-02-24

    This safety analysis is for the SNF Fuel Retrieval (FRS) Sub Project. The FRS equipment will be added to K West and K East Basins to facilitate retrieval, cleaning and repackaging the spent nuclear fuel into Multi-Canister Overpack baskets. The document includes a hazard evaluation, identifies bounding accidents, documents analyses of the accidents and establishes safety class or safety significant equipment to mitigate accidents as needed.

  9. Probability of Criticality for MOX SNF

    International Nuclear Information System (INIS)

    P. Gottlieb

    1999-01-01

    The purpose of this calculation is to provide a conservative (upper bound) estimate of the probability of criticality for mixed oxide (MOX) spent nuclear fuel (SNF) of the Westinghouse pressurized water reactor (PWR) design that has been proposed for use. with the Plutonium Disposition Program (Ref. 1, p. 2). This calculation uses a Monte Carlo technique similar to that used for ordinary commercial SNF (Ref. 2, Sections 2 and 5.2). Several scenarios, covering a range of parameters, are evaluated for criticality. Parameters specifying the loss of fission products and iron oxide from the waste package are particularly important. This calculation is associated with disposal of MOX SNF

  10. Human error prediction and countermeasures based on CREAM in spent nuclear fuel (SNF) transportation

    International Nuclear Information System (INIS)

    Kim, Jae San

    2007-02-01

    Since the 1980s, in order to secure the storage capacity of spent nuclear fuel (SNF) at NPPs, SNF assemblies have been transported on-site from one unit to another unit nearby. However in the future the amount of the spent fuel will approach capacity in the areas used, and some of these SNFs will have to be transported to an off-site spent fuel repository. Most SNF materials used at NPPs will be transported by general cargo ships from abroad, and these SNFs will be stored in an interim storage facility. In the process of transporting SNF, human interactions will involve inspecting and preparing the cask and spent fuel, loading the cask onto the vehicle or ship, transferring the cask as well as storage or monitoring the cask. The transportation of SNF involves a number of activities that depend on reliable human performance. In the case of the transport of a cask, human errors may include spent fuel bundle misidentification or cask transport accidents among others. Reviews of accident events when transporting the Radioactive Material (RAM) throughout the world indicate that human error is the major causes for more than 65% of significant events. For the safety of SNF transportation, it is very important to predict human error and to deduce a method that minimizes the human error. This study examines the human factor effects on the safety of transporting spent nuclear fuel (SNF). It predicts and identifies the possible human errors in the SNF transport process (loading, transfer and storage of the SNF). After evaluating the human error mode in each transport process, countermeasures to minimize the human error are deduced. The human errors in SNF transportation were analyzed using Hollnagel's Cognitive Reliability and Error Analysis Method (CREAM). After determining the important factors for each process, countermeasures to minimize human error are provided in three parts: System design, Operational environment, and Human ability

  11. Causes of Accidents among Commercial Motorcyclists (Okada) in ...

    African Journals Online (AJOL)

    Motor cycle accidents have become the most serious problem threatening the entire Nigerian population. It is against this background that this study attempted to investigate the causes of accidents among commercial motorcyclists in Borno State, Nigeria. The population of the study consisted of all the commercial ...

  12. causes and consequences of commercial motorcycle accidents

    African Journals Online (AJOL)

    PROF EKWUEME

    Accident associated with the use of motorcycle for commercial transportation in Makurdi metropolis was ... deaths, over speeding accounted for 27 percent of accidents and deaths respectively, .... 10. 7. 5. (a). (b). Possession of wing mirror and Crash helmet. Yes. No. 12 .... reduce the risk of serious head and brain injuries.

  13. Site Specific Analyses of a Spent Nuclear Fuel Transportation Accident

    International Nuclear Information System (INIS)

    Biwer, B. M.; Chen, S. Y.

    2003-01-01

    The number of spent nuclear fuel (SNF) shipments is expected to increase significantly during the time period that the United States' inventory of SNF is sent to a final disposal site. Prior work estimated that the highest accident risks of a SNF shipping campaign to the proposed geologic repository at Yucca Mountain were in the corridor states, such as Illinois. The largest potential human health impacts would be expected to occur in areas with high population densities such as urban settings. Thus, our current study examined the human health impacts from the most plausible severe SNF transportation accidents in the Chicago metropolitan area. The RISKIND 2.0 program was used to model site-specific data for an area where the largest impacts might occur. The results have shown that the radiological human health consequences of a severe SNF rail transportation accident on average might be similar to one year of exposure to natural background radiation for those persons living a nd working in the most affected areas downwind of the actual accident location. For maximally exposed individuals, an exposure similar to about two years of exposure to natural background radiation was estimated. In addition to the accident probabilities being very low (approximately 1 chance in 10,000 or less during the entire shipping campaign), the actual human health impacts are expected to be lower if any of the accidents considered did occur, because the results are dependent on the specific location and weather conditions, such as wind speed and direction, that were selected to maximize the results. Also, comparison of the results of longer duration accident scenarios against U.S. Environmental Protection Agency guidelines was made to demonstrate the usefulness of this site-specific analysis for emergency planning purposes

  14. [Factors associated with work-related accidents in the informal commercial sector].

    Science.gov (United States)

    Rios, Marcela Andrade; Nery, Adriana Alves; Rios, Polianna Alves Andrade; Casotti, Cezar Augusto; Cardoso, Jefferson Paixão

    2015-06-01

    This study aimed to estimate the incidence of non-fatal work-related accidents in the informal commercial sector and analyze associated socio-demographic, occupational, workplace, and health factors, in a cross-sectional survey of 434 workers in the business district of Jequié, Bahia State, Brazil, in 2013. Logistic regression was used to assess factors associated with accidents. Incidence of accidents in the previous 12 months was estimated at 32.3%, and multivariate analysis showed higher odds of accidents in male sex workers (OR = 1.61), young individuals (OR = 4.62), meat or poultry workers (OR = 9.55), and workers performing heavy physical work (OR = 1.71). The results show the need for public policies to prevent accidents in the informal commercial sector.

  15. Evaluation of Test Methodologies for Dissolution and Corrosion of Al-SNF

    International Nuclear Information System (INIS)

    Wiersma, B.J.; Mickalonis, J.I.; Louthan, M.R.

    1998-09-01

    The performance of aluminum-based spent nuclear fuel (Al-SNF) in the repository will differ from that of the commercial nuclear fuels and the high level waste glasses. The program consists of evaluating three test methods

  16. Functional identification of an Arabidopsis snf4 ortholog by screening for heterologous multicopy suppressors of snf4 deficiency in yeast

    DEFF Research Database (Denmark)

    Kleinow, T.; Bhalerao, R.; Breuer, F.

    2000-01-01

    Yeast Snf4 is a prototype of activating gamma-subunits of conserved Snf1/AMPK-related protein kinases (SnRKs) controlling glucose and stress signaling in eukaryotes. The catalytic subunits of Arabidopsis SnRKs, AKIN10 and AKIN11, interact with Snf4 and suppress the snf1 and snf4 mutations in yeast....... By expression of an Arabidopsis cDNA library in yeast, heterologous multicopy snf4 suppressors were isolated. In addition to AKIN10 and AKIN11, the deficiency of yeast snf4 mutant to grown on non-fermentable carbon source was suppressed by Arabidopsis Myb30, CAAT-binding factor Hap3b, casein kinase I, zinc......-finger factors AZF2 and ZAT10, as well as orthologs of hexose/UDP-hexose transporters, calmodulin, SMC1-cohesin and Snf4. Here we describe the characterization of AtSNF4, a functional Arabidopsis Snf4 ortholog, that interacts with yeast Snf1 and specifically binds to the C-terminal regulatory domain...

  17. SWI/SNF complex in disorder

    Science.gov (United States)

    Santen, Gijs W.E.; Kriek, Marjolein; van Attikum, Haico

    2012-01-01

    Heterozygous germline mutations in components of switch/sucrose nonfermenting (SWI/SNF) chromatin remodeling complexes were recently identified in patients with non-syndromic intellectual disability, Coffin-Siris syndrome and Nicolaides-Baraitser syndrome. The common denominator of the phenotype of these patients is severe intellectual disability and speech delay. Somatic and germline mutations in SWI/SNF components were previously implicated in tumor development. This raises the question whether patients with intellectual disability caused by SWI/SNF mutations in the germline are exposed to an increased risk of developing cancer. Here we compare the mutational spectrum of SWI/SNF components in intellectual disability syndromes and cancer, and discuss the implications of the results of this comparison for the patients. PMID:23010866

  18. Probabilistic Risk Assessment of Cask Drop Accident during On-site Spent Nuclear Fuel Transportation

    Energy Technology Data Exchange (ETDEWEB)

    Ham, Jae Hyun; Christian, Robby; Momani, Belal Al; Kang, Hyun Gook [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    There are two ways to transfer the SNF from a site to other site, one is land transportation and the other is maritime transportation. Maritime transportation might be used because this way uses more safe route which is far from populated area. The whole transportation process can be divided in two parts: transferring the SNF between SNP and wharf in-Nuclear Power Plant (NPP) site by truck, and transferring the SNF from the wharf to the other wharf by ship. In this research, on-site SNF transportation between SNP and wharf was considered. Two kinds of single accident can occur during this type of SNF transportation, impact and fire, caused by internal events and external events. In this research, PRA of cask drop accident during onsite SNF transportation was done, risk to a person (mSv/person) from a case with specific conditions was calculated. In every 11 FEM simulation drop cases, FDR is 1 even the fuel assemblies are located inside of the cask. It is a quite larger value for all cases than the results with similar drop condition from the reports which covers the PRA on cask storage system. Because different from previous reports, subsequent impact was considered. Like in figure 8, accelerations which are used to calculate the FDR has extremely higher values in subsequent impact than the first impact for all SNF assemblies.

  19. Uranium Oxide Rate Summary for the Spent Nuclear Fuel (SNF) Project (OCRWM)

    Energy Technology Data Exchange (ETDEWEB)

    PAJUNEN, A.L.

    2000-09-20

    The purpose of this document is to summarize the uranium oxidation reaction rate information developed by the Hanford Spent Nuclear Fuel (SNF) Project and describe the basis for selecting reaction rate correlations used in system design. The selection basis considers the conditions of practical interest to the fuel removal processes and the reaction rate application during design studies. Since the reaction rate correlations are potentially used over a range of conditions, depending of the type of evaluation being performed, a method for transitioning between oxidation reactions is also documented. The document scope is limited to uranium oxidation reactions of primary interest to the SNF Project processes. The reactions influencing fuel removal processes, and supporting accident analyses, are: uranium-water vapor, uranium-liquid water, uranium-moist air, and uranium-dry air. The correlation selection basis will consider input from all available sources that indicate the oxidation rate of uranium fuel, including the literature data, confirmatory experimental studies, and fuel element observations. Trimble (2000) summarizes literature data and the results of laboratory scale experimental studies. This document combines the information in Trimble (2000) with larger scale reaction observations to describe uranium oxidation rate correlations applicable to conditions of interest to the SNF Project.

  20. Uranium Oxide Rate Summary for the Spent Nuclear Fuel (SNF) Project (OCRWM)

    International Nuclear Information System (INIS)

    PAJUNEN, A.L.

    2000-01-01

    The purpose of this document is to summarize the uranium oxidation reaction rate information developed by the Hanford Spent Nuclear Fuel (SNF) Project and describe the basis for selecting reaction rate correlations used in system design. The selection basis considers the conditions of practical interest to the fuel removal processes and the reaction rate application during design studies. Since the reaction rate correlations are potentially used over a range of conditions, depending of the type of evaluation being performed, a method for transitioning between oxidation reactions is also documented. The document scope is limited to uranium oxidation reactions of primary interest to the SNF Project processes. The reactions influencing fuel removal processes, and supporting accident analyses, are: uranium-water vapor, uranium-liquid water, uranium-moist air, and uranium-dry air. The correlation selection basis will consider input from all available sources that indicate the oxidation rate of uranium fuel, including the literature data, confirmatory experimental studies, and fuel element observations. Trimble (2000) summarizes literature data and the results of laboratory scale experimental studies. This document combines the information in Trimble (2000) with larger scale reaction observations to describe uranium oxidation rate correlations applicable to conditions of interest to the SNF Project

  1. Dentofacial injuries in commercial motorcycle accidents in Cameroon

    African Journals Online (AJOL)

    Objective: To assess the pattern of dentofacial injuries in commercial motorcycle accidents among riders and passengers in Cameroon. Materials and Methods: This was a hospital based study conducted in 6 out of 10 regional capitals in the months of December 2011 to September 2012. Analyzed information included age, ...

  2. DOE SNF technology development necessary for final disposal

    International Nuclear Information System (INIS)

    Hale, D.L.; Fillmore, D.L.; Windes, W.E.

    1996-01-01

    Existing technology is inadequate to allow safe disposal of the entire inventory of US Department of Energy (DOE) spent nuclear fuel (SNF). Needs for SNF technology development were identified for each individual fuel type in the diverse inventory of SNF generated by past, current, and future DOE materials production, as well as SNF returned from domestic and foreign research reactors. This inventory consists of 259 fuel types with different matrices, cladding materials, meat composition, actinide content, and burnup. Management options for disposal of SNF include direct repository disposal, possible including some physical or chemical preparation, or processing to produce a qualified waste form by using existing aqueous processes or new treatment processes. Technology development needed for direct disposal includes drying, mitigating radionuclide release, canning, stabilization, and characterization technologies. While existing aqueous processing technology is fairly mature, technology development may be needed to apply one of these processes to SNF different than for which the process was originally developed. New processes to treat SNF not suitable for disposal in its current form were identified. These processes have several advantages over existing aqueous processes

  3. SNF Project Engineering Process Improvement Plan

    International Nuclear Information System (INIS)

    DESAI, S.P.

    2000-01-01

    This plan documents the SNF Project activities and plans to support its engineering process. It describes five SNF Project Engineering initiatives: new engineering procedures, qualification cards process; configuration management, engineering self assessments, and integrated schedule for engineering activities

  4. Canister storage building compliance assessment SNF project NRC equivalency criteria - HNF-SD-SNF-DB-003

    International Nuclear Information System (INIS)

    BLACK, D.M.

    1999-01-01

    This document presents the Project's position on compliance with the SNF Project NRC Equivalency Criteria - HNF-SD-SNF-DE-003, Spent Nuclear Fuel Project Path Forward Additional NRC Requirements. No non-compliances are shown. The compliance statements have been reviewed and approved by DOE. Open items are scheduled to be closed prior to project completion

  5. Accident and Off-Normal Response and Recovery from Multi-Canister Overpack (MCO) Processing Events

    International Nuclear Information System (INIS)

    ALDERMAN, C.A.

    2000-01-01

    In the process of removing spent nuclear fuel (SNF) from the K Basins through its subsequent packaging, drymg, transportation and storage steps, the SNF Project must be able to respond to all anticipated or foreseeable off-normal and accident events that may occur. Response procedures and recovery plans need to be in place, personnel training established and implemented to ensure the project will be capable of appropriate actions. To establish suitable project planning, these events must first be identified and analyzed for their expected impact to the project. This document assesses all off-normal and accident events for their potential cross-facility or Multi-Canister Overpack (MCO) process reversal impact. Table 1 provides the methodology for establishing the event planning level and these events are provided in Table 2 along with the general response and recovery planning. Accidents and off-normal events of the SNF Project have been evaluated and are identified in the appropriate facility Safety Analysis Report (SAR) or in the transportation Safety Analysis Report for Packaging (SARP). Hazards and accidents are summarized from these safety analyses and listed in separate tables for each facility and the transportation system in Appendix A, along with identified off-normal events. The tables identify the general response time required to ensure a stable state after the event, governing response documents, and the events with potential cross-facility or SNF process reversal impacts. The event closure is predicated on stable state response time, impact to operations and the mitigated annual occurrence frequency of the event as developed in the hazard analysis process

  6. DESIGN ANALYSIS FOR THE NAVAL SNF WASTE PACKAGE

    International Nuclear Information System (INIS)

    T.L. Mitchell

    2000-01-01

    The purpose of this analysis is to demonstrate the design of the naval spent nuclear fuel (SNF) waste package (WP) using the Waste Package Department's (WPD) design methodologies and processes described in the ''Waste Package Design Methodology Report'' (CRWMS MandO [Civilian Radioactive Waste Management System Management and Operating Contractor] 2000b). The calculations that support the design of the naval SNF WP will be discussed; however, only a sub-set of such analyses will be presented and shall be limited to those identified in the ''Waste Package Design Sensitivity Report'' (CRWMS MandO 2000c). The objective of this analysis is to describe the naval SNF WP design method and to show that the design of the naval SNF WP complies with the ''Naval Spent Nuclear Fuel Disposal Container System Description Document'' (CRWMS MandO 1999a) and Interface Control Document (ICD) criteria for Site Recommendation. Additional criteria for the design of the naval SNF WP have been outlined in Section 6.2 of the ''Waste Package Design Sensitivity Report'' (CRWMS MandO 2000c). The scope of this analysis is restricted to the design of the naval long WP containing one naval long SNF canister. This WP is representative of the WPs that will contain both naval short SNF and naval long SNF canisters. The following items are included in the scope of this analysis: (1) Providing a general description of the applicable design criteria; (2) Describing the design methodology to be used; (3) Presenting the design of the naval SNF waste package; and (4) Showing compliance with all applicable design criteria. The intended use of this analysis is to support Site Recommendation reports and assist in the development of WPD drawings. Activities described in this analysis were conducted in accordance with the technical product development plan (TPDP) ''Design Analysis for the Naval SNF Waste Package (CRWMS MandO 2000a)

  7. Hull loss accident model for narrow body commercial aircraft

    Directory of Open Access Journals (Sweden)

    Somchanok Tiabtiamrat

    2010-10-01

    Full Text Available Accidents with narrow body aircraft were statistically evaluated covering six families of commercial aircraft includingBoeing B737, Airbus A320, McDonnell Douglas MD80, Tupolev TU134/TU154 and Antonov AN124. A risk indicator for eachflight phase was developed based on motion characteristics, duration time, and the presence of adverse weather conditions.The estimated risk levels based on these risk indicators then developed from the risk indicator. Regression analysis indicatedvery good agreement between the estimated risk level and the accident ratio of hull loss cases per number of delivered aircraft.The effect of time on the hull loss accident ratio per delivered aircraft was assessed for B737, A320 and MD80. Equationsrepresenting the effect of time on hull loss accident ratio per delivered aircraft were proposed for B737, A320, and MD80,while average values of hull loss accident ratio per delivered aircraft were found for TU134, TU154, and AN 124. Accidentprobability equations were then developed for each family of aircraft that the probability of an aircraft in a hull loss accidentcould be estimated for any aircraft family, flight phase, presence of adverse weather factor, hour of day, day of week, monthof year, pilot age, and pilot flight hour experience. A simplified relationship between estimated hull loss accident probabilityand unsafe acts by human was proposed. Numerical investigation of the relationship between unsafe acts by human andfatality ratio suggested that the fatality ratio in hull loss accident was dominated primarily by the flight phase media.

  8. Statistical summary of commercial jet aircraft accidents : worldwide operations, 1959-2009

    Science.gov (United States)

    2010-07-01

    The accident statistics presented in this summary are confined to worldwide commercial jet airplanes that are heavier than 60,000 pounds maximum gross weight. Within that set of airplanes, there are two groups excluded: : 1) Airplanes manufactured in...

  9. Design analysis of various transportation package options for BN-350 SNF in terms of nuclear radiation safety in planning for long-terms dry storage

    International Nuclear Information System (INIS)

    Aisabekov, A.Z.; Mukenova, S.A.; Tur, E.S.; Tsyngaev, V.M.

    2004-01-01

    Full text: This effort is performed under the BN-350 reactor facility decommissioning project. One of the project tasks - spent nuclear fuel handling - includes the following: fuel packaging into sealed canisters, transportation of the canisters in multi-seat metallo-concrete containers and placement of the containers for a long-term dry storage. The goal of this effort is to computationally validate nuclear and radiation safety of the SNF containers placed for storage both under normal storage conditions and probable accident situations. The basic unit structure and design configurations are presented: assemblies, canisters, transportation containers. The major factors influencing nuclear and radiation safety are presented: fuel burn-up, enrichment, fabrication tolerance, types of fuel assemblies, configuration of assemblies in the canister and canisters in the container, background of assemblies placed in the reactor and cooling pool. Conditions under which the SNF containers will be stored are described and probable accident situations are listed. Proceeding from the conservatism principle, selection of the assemblies posing the greatest nuclear hazard is validated. A neutron effective multiplication factor is calculated for the SNF containers under the normal storage conditions and for the case of emergency. The effective multiplication factor is shown to be within a standard value of 0.95 in any situation. Based on the experimental data on assembly and canister dose rates, canisters posing the highest radiation threat are selected. Activities of sources and gamma-radiation spectral composition are calculated. Distribution of the dose rate outside the containers both under the normal storage conditions and accident situations are calculated. The results obtained are analyzed

  10. U.S. Commercial Spent Nuclear Fuel Assembly Characteristics - 1968-2013

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jianwei [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Peterson, Joshua L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gauld, Ian C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bowman, Stephen M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-09-01

    Activities related to management of spent nuclear fuel (SNF) are increasing in the US and many other countries. Over 240,000 SNF assemblies have been discharged from US commercial reactors since the late 1960s. The enrichment and burnup of SNF have changed significantly over the past 40 years, and fuel assembly designs have also evolved. Understanding the general characteristics of SNF helps regulators and other stakeholders form overall strategies towards the final disposal of US SNF. This report documents a survey of all US commercial SNF assemblies in the GC-859 database and provides reference SNF source terms (e.g., nuclide inventories, decay heat, and neutron/photon emission) at various cooling times up to 200 years after fuel discharge. This study reviews the distribution and evolution of fuel parameters of all SNF assemblies discharged over the past 40 years. Assemblies were categorized into three groups based on discharge year, and the median burnups and enrichments of each group were used to establish representative cases. An extended burnup case was created for boiling water reactor (BWR) fuels, and another was created for the pressurized water reactor (PWR) fuels. Two additional cases were developed to represent the eight mixed oxide (MOX) fuel assemblies in the database. Burnup calculations were performed for each representative case. Realistic parameters for fuel design and operations were used to model the SNF and to provide reference fuel characteristics representative of the current inventory. Burnup calculations were performed using the ORIGEN code, which is part of the SCALE nuclear modeling and simulation code system. Results include total activity, decay heat, photon emission, neutron flux, gamma heat, and plutonium content, as well as concentrations for 115 significant nuclides. These quantities are important in the design, regulation, and operations of SNF storage, transportation, and disposal systems.

  11. Structure and novel functional mechanism of Drosophila SNF in sex-lethal splicing.

    Directory of Open Access Journals (Sweden)

    Jicheng Hu

    Full Text Available Sans-fille (SNF is the Drosophila homologue of mammalian general splicing factors U1A and U2B'', and it is essential in Drosophila sex determination. We found that, besides its ability to bind U1 snRNA, SNF can also bind polyuridine RNA tracts flanking the male-specific exon of the master switch gene Sex-lethal (Sxl pre-mRNA specifically, similar to Sex-lethal protein (SXL. The polyuridine RNA binding enables SNF directly inhibit Sxl exon 3 splicing, as the dominant negative mutant SNF(1621 binds U1 snRNA but not polyuridine RNA. Unlike U1A, both RNA recognition motifs (RRMs of SNF can recognize polyuridine RNA tracts independently, even though SNF and U1A share very high sequence identity and overall structure similarity. As SNF RRM1 tends to self-associate on the opposite side of the RNA binding surface, it is possible for SNF to bridge the formation of super-complexes between two introns flanking Sxl exon 3 or between a intron and U1 snRNP, which serves the molecular basis for SNF to directly regulate Sxl splicing. Taken together, a new functional model for SNF in Drosophila sex determination is proposed. The key of the new model is that SXL and SNF function similarly in promoting Sxl male-specific exon skipping with SNF being an auxiliary or backup to SXL, and it is the combined dose of SXL and SNF governs Drosophila sex determination.

  12. Hazard Evaluation for Storage of Spent Nuclear Fuel (SNF) Sludge at the Solid Waste Treatment Facility

    International Nuclear Information System (INIS)

    SCHULTZ, M.V.

    2000-01-01

    As part of the Spent Nuclear Fuel (SNF) storage basin clean-up project, sludge that has accumulated in the K Basins due to corrosion of damaged irradiated N Reactor will be loaded into containers and placed in interim storage. The Hanford Site Treatment Complex (T Plant) has been identified as the location where the sludge will be stored until final disposition of the material occurs. Long term storage of sludge from the K Basin fuel storage facilities requires identification and analysis of potential accidents involving sludge storage in T Plant. This report is prepared as the initial step in the safety assurance process described in DOE Order 5480.23, Nuclear Safety Analysis Reports and HNF-PRO-704, Hazards and Accident Analysis Process. This report documents the evaluation of potential hazards and off-normal events associated with sludge storage activities. This information will be used in subsequent safety analyses, design, and operations procedure development to ensure safe storage. The hazards evaluation for the storage of SNF sludge in T-Plant used the Hazards and Operability Analysis (HazOp) method. The hazard evaluation identified 42 potential hazardous conditions. No hazardous conditions involving hazardous/toxic chemical concerns were identified. Of the 42 items identified in the HazOp study, eight were determined to have potential for onsite worker consequences. No items with potential offsite consequences were identified in the HazOp study. Hazardous conditions with potential onsite worker or offsite consequences are candidates for quantitative consequence analysis. The hazardous conditions with potential onsite worker consequences were grouped into two event categories, Container failure due to overpressure - internal to T Plant, and Spill of multiple containers. The two event categories will be developed into accident scenarios that will be quantitatively analyzed to determine release consequences. A third category, Container failure due to

  13. Technology development for DOE SNF management

    International Nuclear Information System (INIS)

    Hale, D.L.; Einziger, R.E.; Murphy, J.R.

    1995-01-01

    This paper describes the process used to identify technology development needs for the same management of spent nuclear fuel (SNF) in the US Department of Energy (DOE) inventory. Needs were assessed for each of the over 250 fuel types stores at DOE sites around the country for each stage of SNF management--existing storage, transportation, interim storage, and disposal. The needs were then placed into functional groupings to facilitate integration and collaboration among the sites

  14. The Snf1 Protein Kinase in the Yeast Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Usaite, Renata

    2008-01-01

    4 on the regulation of glucose and galactose metabolism, I physiologically characterized Δsnf1, Δsnf4, and Δsnfsnf4 CEN.PK background yeast strains in glucose and glucose-galactose mixture batch cultivations (chapter 2). The results of this study showed that delayed induction of galactose...... that the stable isotope labeling approach is highly reproducible among biological replicates when complex protein mixtures containing small expression changes were analyzed. Where poor correlation between stable isotope labeling and spectral counting was found, the major reason behind the discrepancy was the lack...

  15. Road rage and road traffic accidents among commercial vehicle drivers in Lahore, Pakistan.

    Science.gov (United States)

    Shaikh, M A; Shaikh, I A; Siddiqui, Z

    2012-04-01

    Road rage and road traffic accidents increase the burden of morbidity and mortality in a population. A cross-sectional survey with convenience sampling was conducted among commercial vehicle drivers in Lahore, Pakistan (n = 901) to record their behaviours/experiences regarding road rage and road traffic accidents. Respondents were asked about incidents of shouting/cursing/rude gestures or threats to physically hurt the person/vehicle, by others or themselves, in the previous 24 hours or 3 months, and their involvement in road traffic accidents in the previous 12 months. Auto-rickshaw drivers were significantly more likely to report various road rage experiences/behaviours and involvement in accidents compared with bus and wagon drivers. A total of 112 respondents (12.4%) reported being involved in a road traffic accident in the previous 12 months but traffic police did not record the accident in 52.7% of cases. The results of this study underline the need to improve road safety in Pakistan.

  16. Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae.

    Science.gov (United States)

    Elbing, Karin; McCartney, Rhonda R; Schmidt, Martin C

    2006-02-01

    Members of the Snf1/AMPK family of protein kinases are activated by distinct upstream kinases that phosphorylate a conserved threonine residue in the Snf1/AMPK activation loop. Recently, the identities of the Snf1- and AMPK-activating kinases have been determined. Here we describe the purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. The identities of proteins associated with the Snf1-activating kinases were determined by peptide mass fingerprinting. These kinases, Sak1, Tos3 and Elm2 do not appear to require the presence of additional subunits for activity. Sak1 and Snf1 co-purify and co-elute in size exclusion chromatography, demonstrating that these two proteins form a stable complex. The Snf1-activating kinases phosphorylate the activation loop threonine of Snf1 in vitro with great specificity and are able to do so in the absence of beta and gamma subunits of the Snf1 heterotrimer. Finally, we showed that the Snf1 kinase domain isolated from bacteria as a GST fusion protein can be activated in vitro and shows substrate specificity in the absence of its beta and gamma subunits.

  17. Current state of WWER SNF storage in Russia and the perspectives

    International Nuclear Information System (INIS)

    Anisimov, O.; Kozlov, Y.; Razmashkin, N.; Safutin, V.; Tikhonov, N.

    2006-01-01

    In the Russian Federation WWER-440 Spent Nuclear Fuel (SNF) is reprocessed at RT-1 plant near Cheliabinsk. WWER-1000 SNF is supposed to be reprocessed at RT-2 plant, which will be built about 2020. The information on the capacity and fill up level of the at-reactor pools at NPP with WWER reactors considering its modification up to May 2005 is given. The regulatory requirements to all SNF 'wet' storage facilities; the principle design and engineering solutions as well as the complex of measures for radiation safety and the environmental protection of spent fuel storage are presented. WWER-440 SNF management, WWER-1000 SNF management and dry storage of WWER-1000 SNF are discussed. In the conclusion it is noted than neither Russia, nor any other country have the experience of construction of vault-type 'dry' storage facilities of such a capacity to store WWER-1000 SNF (9000 tU). The experience and design solutions approved earlier in creation of other dangerous facilities were used. The calculations were based on conservative assumptions allowing with a large assurance to guarantee the nuclear and radiation safety and the environmental protection. At present, a program is developed for scientific-technical support of the dry storage facility design and operation, aimed at the studies whose results will allow to optimize the taken technical decisions, simplify SNF management technology and, possibly, to reduce the cost of the storage facility itself

  18. Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae

    OpenAIRE

    Elbing, Karin; McCartney, Rhonda R.; Schmidt, Martin C.

    2006-01-01

    Members of the Snf1/AMPK family of protein kinases are activated by distinct upstream kinases that phosphorylate a conserved threonine residue in the Snf1/AMPK activation loop. Recently, the identities of the Snf1- and AMPK-activating kinases have been determined. Here we describe the purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. The identities of proteins associated with the Snf1-activating kinases were determined by peptide mass fingerpr...

  19. Subunits of the Snf1 kinase heterotrimer show interdependence for association and activity.

    Science.gov (United States)

    Elbing, Karin; Rubenstein, Eric M; McCartney, Rhonda R; Schmidt, Martin C

    2006-09-08

    The Snf1 kinase and its mammalian orthologue, the AMP-activated protein kinase (AMPK), function as heterotrimers composed of a catalytic alpha-subunit and two non-catalytic subunits, beta and gamma. The beta-subunit is thought to hold the complex together and control subcellular localization whereas the gamma-subunit plays a regulatory role by binding to and blocking the function of an auto-inhibitory domain (AID) present in the alpha-subunit. In addition, catalytic activity requires phosphorylation by a distinct upstream kinase. In yeast, any one of three Snf1-activating kinases, Sak1, Tos3, or Elm1, can fulfill this role. We have previously shown that Sak1 is the only Snf1-activating kinase that forms a stable complex with Snf1. Here we show that the formation of the Sak1.Snf1 complex requires the beta- and gamma-subunits in vivo. However, formation of the Sak1.Snf1 complex is not necessary for glucose-regulated phosphorylation of the Snf1 activation loop. Snf1 kinase purified from cells lacking the beta-subunits do not contain any gamma-subunit, indicating that the Snf1 kinase does not form a stable alphagamma dimer in vivo. In vitro kinase assays using purified full-length and truncated Snf1 proteins demonstrate that the kinase domain, which lacks the AID, is significantly more active than the full-length Snf1 protein. Addition of purified beta- and gamma-subunits could stimulate the kinase activity of the full-length alpha-subunit but only when all three subunits were present, suggesting an interdependence of all three subunits for assembly of a functional complex.

  20. Sp1 and CREB regulate basal transcription of the human SNF2L gene

    International Nuclear Information System (INIS)

    Xia Yu; Jiang Baichun; Zou Yongxin; Gao Guimin; Shang Linshan; Chen Bingxi; Liu Qiji; Gong Yaoqin

    2008-01-01

    Imitation Switch (ISWI) is a member of the SWI2/SNF2 superfamily of ATP-dependent chromatin remodelers, which are involved in multiple nuclear functions, including transcriptional regulation, replication, and chromatin assembly. Mammalian genomes encode two ISWI orthologs, SNF2H and SNF2L. In order to clarify the molecular mechanisms governing the expression of human SNF2L gene, we functionally examined the transcriptional regulation of human SNF2L promoter. Reporter gene assays demonstrated that the minimal SNF2L promoter was located between positions -152 to -86 relative to the transcription start site. In this region we have identified a cAMP-response element (CRE) located at -99 to -92 and a Sp1-binding site at -145 to -135 that play a critical role in regulating basal activity of human SNF2L gene, which were proven by deletion and mutation of specific binding sites, EMSA, and down-regulating Sp1 and CREB via RNAi. This study provides the first insight into the mechanisms that control basal expression of human SNF2L gene

  1. Complexon Solutions in Freon for Decontamination of Solids and SNF Treatment

    International Nuclear Information System (INIS)

    Kamachev, V.; Shadrin, A.; Murzin, A.

    2008-01-01

    Full text of publication follows: The possibility of using complexon solutions in supercritical and compressed carbon dioxide for decontamination of solid surfaces and for spent nuclear fuel (SNF) treatment was demonstrated in the works of Japanese, Russian and American researchers. The obtained data showed that the use of complexon solutions in carbon dioxide sharply decreases the volume of secondary radioactive wastes because it can be easily evaporated, purified and recycled. Moreover, high penetrability of carbon dioxide allows decontamination of surfaces with complex shape. However, one of the disadvantages of carbon dioxide is its high working pressure (10-20 MPa for supercritical CO 2 and 7 MPa for compressed CO 2 ). Moreover, in case of SNF treatment, carbon dioxide solvent will be contaminated with 14 C, which in the course of SNF dissolution in CO 2 containing TBP*HNO 3 adduct stage will be oxidized into CO 2 . These main disadvantages can be eliminated by using complexon solutions in ozone-friendly Freon HFC-134a for decontamination and SNF treatment. Our experimental data for real contaminated materials showed that the decontamination factor for complexon solutions in liquid Freon HFC-134a at 1,2 MPa and 25 deg. C is close to that attained in carbon dioxide. Moreover, the possibility of SNF treatment in Freon HFC-134a was demonstrated in trials using real SNF and its imitators. (authors)

  2. Spent Nuclear Fuel (SNF) Startup Plan to Operations

    International Nuclear Information System (INIS)

    GREGORY, J.R.

    2000-01-01

    This plan defines the approach that will be used to ensure the transition from initial startup to normal operations of the SNF operations--are performed in a safe, controlled, and deliberate manner. It provides a phased approach that bridges the operations between the completion of the ORR and the return to normal operations. This plan includes management oversight and administrative controls to be implemented and then reduced in a controlled manner until normal operations are authorized by SNF Management

  3. An assessment of KW Basin radionuclide activity when opening SNF canisters

    International Nuclear Information System (INIS)

    Bergmann, D.W.; Mollerus, F.J.; Wray, J.L.

    1995-01-01

    N Reactor spent fuel is being stored in sealed canisters in the KW Basin. Some of the canisters contain damaged fuel elements. There is the potential for release of Cs 137, Kr 85, H3, and other fission products and transuranics (TRUs) when canisters are opened. Canister opening is required to select and transfer fuel elements to the 300 Area for examination as part of the Spent Nuclear Fuel (SNF) Characterization program. This report estimates the amount of radionuclides that can be released from Mark II spent nuclear fuel (SNF) canisters in KW Basin when canisters are opened for SNF fuel sampling as part of the SNF Characterization Program. The report also assesses the dose consequences of the releases and steps that can be taken to reduce the impacts of these releases

  4. Trehalose-6-phosphate synthesis controls yeast gluconeogenesis downstream and independent of SNF1.

    Science.gov (United States)

    Deroover, Sofie; Ghillebert, Ruben; Broeckx, Tom; Winderickx, Joris; Rolland, Filip

    2016-06-01

    Trehalose-6-P (T6P), an intermediate of trehalose biosynthesis, was identified as an important regulator of yeast sugar metabolism and signaling. tps1Δ mutants, deficient in T6P synthesis (TPS), are unable to grow on rapidly fermentable medium with uncontrolled influx in glycolysis, depletion of ATP and accumulation of sugar phosphates. However, the exact molecular mechanisms involved are not fully understood. We show that SNF1 deletion restores the tps1Δ growth defect on glucose, suggesting that lack of TPS hampers inactivation of SNF1 or SNF1-regulated processes. In addition to alternative, non-fermentable carbon metabolism, SNF1 controls two major processes: respiration and gluconeogenesis. The tps1Δ defect appears to be specifically associated with deficient inhibition of gluconeogenesis, indicating more downstream effects. Consistently, Snf1 dephosphorylation and inactivation on glucose medium are not affected, as confirmed with an in vivo Snf1 activity reporter. Detailed analysis shows that gluconeogenic Pck1 and Fbp1 expression, protein levels and activity are not repressed upon glucose addition to tps1Δ cells, suggesting a link between the metabolic defect and persistent gluconeogenesis. While SNF1 is essential for induction of gluconeogenesis, T6P/TPS is required for inactivation of gluconeogenesis in the presence of glucose, downstream and independent of SNF1 activity and the Cat8 and Sip4 transcription factors. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. Co-evolution of SNF spliceosomal proteins with their RNA targets in trans-splicing nematodes.

    Science.gov (United States)

    Strange, Rex Meade; Russelburg, L Peyton; Delaney, Kimberly J

    2016-08-01

    Although the mechanism of pre-mRNA splicing has been well characterized, the evolution of spliceosomal proteins is poorly understood. The U1A/U2B″/SNF family (hereafter referred to as the SNF family) of RNA binding spliceosomal proteins participates in both the U1 and U2 small interacting nuclear ribonucleoproteins (snRNPs). The highly constrained nature of this system has inhibited an analysis of co-evolutionary trends between the proteins and their RNA binding targets. Here we report accelerated sequence evolution in the SNF protein family in Phylum Nematoda, which has allowed an analysis of protein:RNA co-evolution. In a comparison of SNF genes from ecdysozoan species, we found a correlation between trans-splicing species (nematodes) and increased phylogenetic branch lengths of the SNF protein family, with respect to their sister clade Arthropoda. In particular, we found that nematodes (~70-80 % of pre-mRNAs are trans-spliced) have experienced higher rates of SNF sequence evolution than arthropods (predominantly cis-spliced) at both the nucleotide and amino acid levels. Interestingly, this increased evolutionary rate correlates with the reliance on trans-splicing by nematodes, which would alter the role of the SNF family of spliceosomal proteins. We mapped amino acid substitutions to functionally important regions of the SNF protein, specifically to sites that are predicted to disrupt protein:RNA and protein:protein interactions. Finally, we investigated SNF's RNA targets: the U1 and U2 snRNAs. Both are more divergent in nematodes than arthropods, suggesting the RNAs have co-evolved with SNF in order to maintain the necessarily high affinity interaction that has been characterized in other species.

  6. Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator

    Science.gov (United States)

    Usaite, Renata; Jewett, Michael C; Oliveira, Ana Paula; Yates, John R; Olsson, Lisbeth; Nielsen, Jens

    2009-01-01

    Highly conserved among eukaryotic cells, the AMP-activated kinase (AMPK) is a central regulator of carbon metabolism. To map the complete network of interactions around AMPK in yeast (Snf1) and to evaluate the role of its regulatory subunit Snf4, we measured global mRNA, protein and metabolite levels in wild type, Δsnf1, Δsnf4, and Δsnfsnf4 knockout strains. Using four newly developed computational tools, including novel DOGMA sub-network analysis, we showed the benefits of three-level ome-data integration to uncover the global Snf1 kinase role in yeast. We for the first time identified Snf1's global regulation on gene and protein expression levels, and showed that yeast Snf1 has a far more extensive function in controlling energy metabolism than reported earlier. Additionally, we identified complementary roles of Snf1 and Snf4. Similar to the function of AMPK in humans, our findings showed that Snf1 is a low-energy checkpoint and that yeast can be used more extensively as a model system for studying the molecular mechanisms underlying the global regulation of AMPK in mammals, failure of which leads to metabolic diseases. PMID:19888214

  7. Identification of multiple distinct Snf2 subfamilies with conserved structural motifs.

    Science.gov (United States)

    Flaus, Andrew; Martin, David M A; Barton, Geoffrey J; Owen-Hughes, Tom

    2006-01-01

    The Snf2 family of helicase-related proteins includes the catalytic subunits of ATP-dependent chromatin remodelling complexes found in all eukaryotes. These act to regulate the structure and dynamic properties of chromatin and so influence a broad range of nuclear processes. We have exploited progress in genome sequencing to assemble a comprehensive catalogue of over 1300 Snf2 family members. Multiple sequence alignment of the helicase-related regions enables 24 distinct subfamilies to be identified, a considerable expansion over earlier surveys. Where information is known, there is a good correlation between biological or biochemical function and these assignments, suggesting Snf2 family motor domains are tuned for specific tasks. Scanning of complete genomes reveals all eukaryotes contain members of multiple subfamilies, whereas they are less common and not ubiquitous in eubacteria or archaea. The large sample of Snf2 proteins enables additional distinguishing conserved sequence blocks within the helicase-like motor to be identified. The establishment of a phylogeny for Snf2 proteins provides an opportunity to make informed assignments of function, and the identification of conserved motifs provides a framework for understanding the mechanisms by which these proteins function.

  8. Evaluation of Neutron Poison Materials for DOE SNF Disposal Systems

    International Nuclear Information System (INIS)

    Vinson, D.W.; Caskey, G.R. Jr.; Sindelar, R.L.

    1998-09-01

    Aluminum-based spent nuclear fuel (Al-SNF) from foreign and domestic research reactors is being consolidated at the Savannah River Site (SRS) for ultimate disposal in the Mined Geologic Disposal System (MGDS). Most of the aluminum-based fuel material contains highly enriched uranium (HEU) (more than 20 percent 235U), which challenges the preclusion of criticality events for disposal periods exceeding 10,000 years. Recent criticality analyses have shown that the addition of neutron absorbing materials (poisons) is needed in waste packages containing DOE SNF canisters fully loaded with Al-SNF under flooded and degraded configurations to demonstrate compliance with the requirement that Keff less than 0.95. Compatibility of poison matrix materials and the Al-SNF, including their relative degradation rate and solubility, are important to maintain criticality control. An assessment of the viability of poison and matrix materials has been conducted, and an experimental corrosion program has been initiated to provide data on degradation rates of poison and matrix materials and Al-SNF materials under repository relevant vapor and aqueous environments. Initial testing includes Al6061, Type 316L stainless steel, and A516Gr55 in synthesized J-13 water vapor at 50 degrees C, 100 degrees C, and 200 degrees C and in condensate water vapor at 100 degrees C. Preliminary results are presented herein

  9. Alteration to the SWI/SNF complex in human cancers

    Directory of Open Access Journals (Sweden)

    Vanessa S. Gordon

    2011-12-01

    Full Text Available The SWI/SNF complex is a key catalyst for gene expression and regulates a variety of pathways, many of which have anticancer roles. Its central roles in cellular growth control, DNA repair, differentiation, cell adhesion and development are often targeted, and inactivated, during cancer development and progression. In this review, we will discuss what is known about how SWI/SNF is inactivated, and describe the potential impact of abrogating this complex. BRG1 and BRM are the catalytic subunits which are essential for SWI/SNF function, and thus, it is not surprising that they are lost in a variety of cancer types. As neither gene is mutated when lost, the mechanism of suppression, as well as the impact of potential gene activity restoration, are reviewed.

  10. Status of burnup credit for transport of SNF in the United States

    International Nuclear Information System (INIS)

    Parks, C.V.; Wagner, J.C.

    2004-01-01

    Allowing credit for the reduction in reactivity associated with fuel depletion can enable more cost-effective, higher-density storage, transportation, and disposal of spent nuclear fuel (SNF) while maintaining a subcritical margin sufficient to establish an adequate safety basis. This paper reviews the current status of burnup credit applied to the design and transport of SNF casks in the United States. The existing U.S. regulatory guidance on burnup credit is limited to pressurized-water-reactor (PWR) fuel and to allowing credit only for actinides in the SNF. By comparing loading curves against actual SNF discharge data for U.S. reactors, the potential benefits that can be realized using the current regulatory guidance with actinide-only burnup credit are illustrated in terms of the inventory allowed in high-capacity casks and the concurrent reduction in SNF shipments. The additional benefits that might be realized by extending burnup credit to credit for select fission products are also illustrated. The curves show that, although fission products in SNF provide a small decrease in reactivity compared with actinides, the additional negative reactivity causes the SNF inventory acceptable for transportation to increase from roughly 30% to approximately 90% when fission products are considered. A savings of approximately $150M in transport costs can potentially be realized for the planned inventory of the repository. Given appropriate experimental data to support code validation, a realistic best-estimate analysis of burnup credit that includes validated credit for fission products is the enhancement that will yield the most significant impact on future transportation plans

  11. SNF shipping cask shielding analysis

    International Nuclear Information System (INIS)

    Johnson, J.O.; Pace, J.V. III.

    1996-01-01

    The Waste Management and Remedial Action Division has planned a modification sequence for storage facility 7827 in the Solid Waste Storage Area (SWSA). The modification cycle is: (1) modify an empty caisson, (2) transfer the spent nuclear fuel (SNF) of an occupied caisson to a hot cell in building 3525 for inspection and possible repackaging, and (3) return the package to the modified caisson in the SWSA. Although the SNF to be moved is in the solid form, it has different levels of activity. Thus, the following 5 shipping casks will be available for the task: the Loop Transport Carrier, the In- Pile Loop LITR HB-2 Carrier, the 6.5-inch HRLEL Carrier, the HFIR Hot Scrap Carrier, and the 10-inch ORR Experiment Removal Shield Cask. This report describes the shielding tasks for the 5 casks: determination of shielding characteristics, any streaming avenues, estimation of thermal limits, and shielding calculational uncertainty for use in the transportation plan

  12. Regulatory practices of radiation safety of SNF transportation in Russia

    International Nuclear Information System (INIS)

    Kuryndina, Lidia; Kuryndin, Anton; Stroganov, Anatoly

    2008-01-01

    This paper overviews current regulatory practices for the assurance of nuclear and radiation safety during railway transportation of SNF on the territory of Russian Federation from NPPs to longterm-storage of reprocessing sites. The legal and regulatory requirements (mostly compliant with IAEA ST-1), licensing procedure for NM transportation are discussed. The current procedure does not require a regulatory approval for each particular shipment if the SNF fully comply with the Rosatom's branch standard and is transported in approved casks. It has been demonstrated that SNF packages compliant with the branch standard, which is knowingly provide sufficient safety margin, will conform to the federal level regulations. The regulatory approval is required if a particular shipment does not comply with the branch standard. In this case, the shipment can be approved only after regulatory review of Applicant's documents to demonstrate that the shipment still conformant to the higher level (federal) regulations. The regulatory review frequently needs a full calculation test of the radiation safety assurance. This test can take a lot of time. That's why the special calculation tools were created in SEC NRS. These tools aimed for precision calculation of the radiation safety parameters by SNF transportation use preliminary calculated Green's functions. Such approach allows quickly simulate any source distribution and optimize spent fuel assemblies placement in cask due to the transport equation property of linearity relatively the source. The short description of calculation tools are presented. Also, the paper discusses foreseen implications related to transportation of mixed-oxide SNF. (author)

  13. Characterization Program Management Plan for Hanford K Basin Spent Nuclear Fuel (SNF) (OCRWM)

    International Nuclear Information System (INIS)

    BAKER, R.B.; TRIMBLE, D.J.

    2000-01-01

    The management plan developed to characterize the K Basin spent nuclear fuel (SNF) and sludge was originally developed for Westinghouse Hanford Company and Pacific Northwest National Laboratory to work together on a program to provide characterization data to support removal, conditioning, and subsequent dry storage of the SNF stored at the Hanford K Basins. The plan also addressed necessary characterization for the removal, transport, and storage of the sludge from the Hanford K Basins. This plan was revised in 1999 (i.e., Revision 2) to incorporate actions necessary to respond to the deficiencies revealed as the result of Quality Assurance surveillances and audits in 1999 with respect to the fuel characterization activities. Revision 3 to this Program Management Plan responds to a Worker Assessment resolution determined in Fical Year 2000. This revision includes an update to current organizational structures and other revisions needed to keep this management plan consistent with the current project scope. The plan continues to address both the SNF and the sludge accumulated at K Basins. Most activities for the characterization of the SNF have been completed. Data validation, Office of Civilian Radioactive Waste Management (OCRWM) document reviews, and OCRWM data qualification are the remaining SNF characterization activities. The transport and storage of K Basin sludge are affected by recent path forward revisions. These revisions require additional laboratory analyses of the sludge to complete the acquisition of required supporting engineering data. Hence, this revision of the management plan provides the overall work control for these remaining SNF and sludge characterization activities given the current organizational structure of the SNF Project

  14. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Executive summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1975-10-01

    The Reactor Safety Study was sponsored by the U. S. Atomic Energy Commission to estimate the public risks that could be involved in potential accidents in commercial nuclear power plants of the type now in use. It was performed under the independent direction of Professor Norman C. Rasmussen of the Massachusetts Institute of Technology. The risks had to be estimated, rather than measured, because although there are about 50 such plants now operating, there have been no nuclear accidents to date resulting in significant releases of radioactivity in U.S. commercial nuclear power plants. The objective of the study was to make a realistic estimate of these risks and, to provide perspective, to compare them with non-nuclear risks to which our society and its individuals are already exposed. This information may be of help in determining the future reliance by society on nuclear power as a source of electricity. The results from this study suggest that the risks to the public from potential accidents in nuclear power plants are comparatively small.

  15. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Executive summary

    International Nuclear Information System (INIS)

    1975-10-01

    The Reactor Safety Study was sponsored by the U. S. Atomic Energy Commission to estimate the public risks that could be involved in potential accidents in commercial nuclear power plants of the type now in use. It was performed under the independent direction of Professor Norman C. Rasmussen of the Massachusetts Institute of Technology. The risks had to be estimated, rather than measured, because although there are about 50 such plants now operating, there have been no nuclear accidents to date resulting in significant releases of radioactivity in U.S. commercial nuclear power plants. The objective of the study was to make a realistic estimate of these risks and, to provide perspective, to compare them with non-nuclear risks to which our society and its individuals are already exposed. This information may be of help in determining the future reliance by society on nuclear power as a source of electricity. The results from this study suggest that the risks to the public from potential accidents in nuclear power plants are comparatively small

  16. Extracellular Matrix-Regulated Gene Expression RequiresCooperation of SWI/SNF and Transcription Factors

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Ren; Spencer, Virginia A.; Bissell, Mina J.

    2006-05-25

    Extracellular cues play crucial roles in the transcriptional regulation of tissue-specific genes, but whether and how these signals lead to chromatin remodeling is not understood and subject to debate. Using chromatin immunoprecipitation (ChIP) assays and mammary-specific genes as models, we show here that extracellular matrix (ECM) molecules and prolactin cooperate to induce histone acetylation and binding of transcription factors and the SWI/SNF complex to the {beta}- and ?-casein promoters. Introduction of a dominant negative Brg1, an ATPase subunit of SWI/SNF complex, significantly reduced both {beta}- and ?-casein expression, suggesting that SWI/SNF-dependent chromatin remodeling is required for transcription of mammary-specific genes. ChIP analyses demonstrated that the ATPase activity of SWI/SNF is necessary for recruitment of RNA transcriptional machinery, but not for binding of transcription factors or for histone acetylation. Coimmunoprecipitation analyses showed that the SWI/SNF complex is associated with STAT5, C/EBP{beta}, and glucocorticoid receptor (GR). Thus, ECM- and prolactin-regulated transcription of the mammary-specific casein genes requires the concerted action of chromatin remodeling enzymes and transcription factors.

  17. White Paper: Multi-purpose canister (MPC) for DOE-owned spent nuclear fuel (SNF)

    International Nuclear Information System (INIS)

    Knecht, D.A.

    1994-04-01

    The paper examines the issue, What are the advantages, disadvantages, and other considerations for using the MPC concept as part of the strategy for interim storage and disposal of DOE-owned SNF? The paper is based in part on the results of an evaluation made for the DOE National Spent Fuel Program by the Waste Form Barrier/Canister Team, which is composed of knowledgeable DOE and DOE-contractor personnel. The paper reviews the MPC and DOE SNF status, provides criteria and other considerations applicable to the issue, and presents an evaluation, conclusions, and recommendations. The primary conclusion is that while most of DOE SNF is not currently sufficiently characterized to be sealed into an MPC, the advantages of standardized packages in handling, reduced radiation exposure, and improved human factors should be considered in DOE SNF program planning. While the design of MPCs for DOE SNF are likely premature at this time, the use of canisters should be considered which are consistent with interim storage options and the MPC design envelope

  18. Main Principles of the Perspective System of SNF Management in Russia - 13333

    International Nuclear Information System (INIS)

    Baryshnikov, Mikhail

    2013-01-01

    For the last several years the System of the Spent Nuclear Fuel management in Russia was seriously changed. The paper describes the main principles of the changes and the bases of the Perspective System of SNF Management in Russia. Among such the bases there are the theses with the interesting names like 'total knowledge', 'pollutant pays' and 'pay and forget'. There is also a brief description of the modern Russian SNF Management Infrastructure. And an outline of the whole System. The System which is - in case of Russia - is quite necessary to adjust SNF accumulation and to utilize the nuclear heritage. (authors)

  19. Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases

    Science.gov (United States)

    Crozet, Pierre; Margalha, Leonor; Confraria, Ana; Rodrigues, Américo; Martinho, Cláudia; Adamo, Mattia; Elias, Carlos A.; Baena-González, Elena

    2014-01-01

    The SNF1 (sucrose non-fermenting 1)-related protein kinases 1 (SnRKs1) are the plant orthologs of the budding yeast SNF1 and mammalian AMPK (AMP-activated protein kinase). These evolutionarily conserved kinases are metabolic sensors that undergo activation in response to declining energy levels. Upon activation, SNF1/AMPK/SnRK1 kinases trigger a vast transcriptional and metabolic reprograming that restores energy homeostasis and promotes tolerance to adverse conditions, partly through an induction of catabolic processes and a general repression of anabolism. These kinases typically function as a heterotrimeric complex composed of two regulatory subunits, β and γ, and an α-catalytic subunit, which requires phosphorylation of a conserved activation loop residue for activity. Additionally, SNF1/AMPK/SnRK1 kinases are controlled by multiple mechanisms that have an impact on kinase activity, stability, and/or subcellular localization. Here we will review current knowledge on the regulation of SNF1/AMPK/SnRK1 by upstream components, post-translational modifications, various metabolites, hormones, and others, in an attempt to highlight both the commonalities of these essential eukaryotic kinases and the divergences that have evolved to cope with the particularities of each one of these systems. PMID:24904600

  20. Aspen Forest Cover by Stratum/Plot (SNF)

    Data.gov (United States)

    National Aeronautics and Space Administration — Average percent coverage and standard deviation of each canopy stratum from subplots at each aspen site during the SNF study in the Superior National Forest, Minnesota

  1. SNF5 is an essential executor of epigenetic regulation during differentiation.

    Science.gov (United States)

    You, Jueng Soo; De Carvalho, Daniel D; Dai, Chao; Liu, Minmin; Pandiyan, Kurinji; Zhou, Xianghong J; Liang, Gangning; Jones, Peter A

    2013-04-01

    Nucleosome occupancy controls the accessibility of the transcription machinery to DNA regulatory regions and serves an instructive role for gene expression. Chromatin remodelers, such as the BAF complexes, are responsible for establishing nucleosome occupancy patterns, which are key to epigenetic regulation along with DNA methylation and histone modifications. Some reports have assessed the roles of the BAF complex subunits and stemness in murine embryonic stem cells. However, the details of the relationships between remodelers and transcription factors in altering chromatin configuration, which ultimately affects gene expression during cell differentiation, remain unclear. Here for the first time we demonstrate that SNF5, a core subunit of the BAF complex, negatively regulates OCT4 levels in pluripotent cells and is essential for cell survival during differentiation. SNF5 is responsible for generating nucleosome-depleted regions (NDRs) at the regulatory sites of OCT4 repressed target genes such as PAX6 and NEUROG1, which are crucial for cell fate determination. Concurrently, SNF5 closes the NDRs at the regulatory regions of OCT4-activated target genes such as OCT4 itself and NANOG. Furthermore, using loss- and gain-of-function experiments followed by extensive genome-wide analyses including gene expression microarrays and ChIP-sequencing, we highlight that SNF5 plays dual roles during differentiation by antagonizing the expression of genes that were either activated or repressed by OCT4, respectively. Together, we demonstrate that SNF5 executes the switch between pluripotency and differentiation.

  2. SNF5 is an essential executor of epigenetic regulation during differentiation.

    Directory of Open Access Journals (Sweden)

    Jueng Soo You

    2013-04-01

    Full Text Available Nucleosome occupancy controls the accessibility of the transcription machinery to DNA regulatory regions and serves an instructive role for gene expression. Chromatin remodelers, such as the BAF complexes, are responsible for establishing nucleosome occupancy patterns, which are key to epigenetic regulation along with DNA methylation and histone modifications. Some reports have assessed the roles of the BAF complex subunits and stemness in murine embryonic stem cells. However, the details of the relationships between remodelers and transcription factors in altering chromatin configuration, which ultimately affects gene expression during cell differentiation, remain unclear. Here for the first time we demonstrate that SNF5, a core subunit of the BAF complex, negatively regulates OCT4 levels in pluripotent cells and is essential for cell survival during differentiation. SNF5 is responsible for generating nucleosome-depleted regions (NDRs at the regulatory sites of OCT4 repressed target genes such as PAX6 and NEUROG1, which are crucial for cell fate determination. Concurrently, SNF5 closes the NDRs at the regulatory regions of OCT4-activated target genes such as OCT4 itself and NANOG. Furthermore, using loss- and gain-of-function experiments followed by extensive genome-wide analyses including gene expression microarrays and ChIP-sequencing, we highlight that SNF5 plays dual roles during differentiation by antagonizing the expression of genes that were either activated or repressed by OCT4, respectively. Together, we demonstrate that SNF5 executes the switch between pluripotency and differentiation.

  3. Vertical Drop of the Naval SNF Long Waste Package On Unyielding Surface

    International Nuclear Information System (INIS)

    S. Mastilovic

    2006-01-01

    The purpose of this calculation is to determine the structural response of a Naval SNF (Spent Nuclear Fuel) Long Waste Package (WP) subjected to 2 m-vertical drop on unyielding surface (US). The scope of this document is limited to reporting the calculation results in terms of maximum stress intensities. This calculation is associated with the waste package design; calculation is performed by the Waste Package Design group. AP-3.12Q, Revision 0, ICN 0, Calculations, is used to perform the calculation and develop the document. The finite element calculation is performed by using the commercially available ANSYS Version (V) 5.4 finite element code. The result of this calculation is provided in terms of maximum stress intensities

  4. Spent Nuclear Fuel (SNF) Project Product Specification

    International Nuclear Information System (INIS)

    PAJUNEN, A.L.

    2000-01-01

    The process for removal of Spent Nuclear Fuel (SNF) from the K Basins has been divided into major sub-systems. The Fuel Retrieval System (FRS) removes fuel from the existing storage canisters, cleans it, and places it into baskets. The multi-canister overpack (MCO) loading system places the baskets into an MCO that has been pre-loaded in a cask. The cask, containing a loaded MCO, is then transferred to the Cold Vacuum Drying (CVD) Facility. After drying at the CVD Facility, the cask, and MCO, are transferred to the Canister Storage Building (CSB), where the MCO is removed from the cask, staged, inspected, sealed (by welding), and stored until a suitable permanent disposal option is implemented. The purpose of this document is to specify the process related characteristics of an MCO at the interface between major process systems. The characteristics are derived from the primary technical documents that form the basis for safety analysis and design calculations. This document translates the calculation assumptions into implementation requirements and describes the method of verifying that the requirement is achieved. These requirements are used to define validation test requirements and describe requirements that influence multiple sub-project safety analysis reports. This product specification establishes limits and controls for each significant process parameter at interfaces between major sub-systems that potentially affect the overall safety and/or quality of the SNF packaged for processing, transport, and interim dry storage. The product specifications in this document cover the SNF packaged in MCOs to be transported throughout the SNF Project. The description of the product specifications are organized in the document as follows: Section 2.0--Summary listing of product specifications at each major sub-system interface. Section 3.0--Summary description providing guidance as to how specifications are complied with by equipment design or processing within a major

  5. Spent Nuclear Fuel (SNF) Project Product Specification

    Energy Technology Data Exchange (ETDEWEB)

    PAJUNEN, A.L.

    2000-12-07

    The process for removal of Spent Nuclear Fuel (SNF) from the K Basins has been divided into major sub-systems. The Fuel Retrieval System (FRS) removes fuel from the existing storage canisters, cleans it, and places it into baskets. The multi-canister overpack (MCO) loading system places the baskets into an MCO that has been pre-loaded in a cask. The cask, containing a loaded MCO, is then transferred to the Cold Vacuum Drying (CVD) Facility. After drying at the CVD Facility, the cask, and MCO, are transferred to the Canister Storage Building (CSB), where the MCO is removed from the cask, staged, inspected, sealed (by welding), and stored until a suitable permanent disposal option is implemented. The purpose of this document is to specify the process related characteristics of an MCO at the interface between major process systems. The characteristics are derived from the primary technical documents that form the basis for safety analysis and design calculations. This document translates the calculation assumptions into implementation requirements and describes the method of verifying that the requirement is achieved. These requirements are used to define validation test requirements and describe requirements that influence multiple sub-project safety analysis reports. This product specification establishes limits and controls for each significant process parameter at interfaces between major sub-systems that potentially affect the overall safety and/or quality of the SNF packaged for processing, transport, and interim dry storage. The product specifications in this document cover the SNF packaged in MCOs to be transported throughout the SNF Project. The description of the product specifications are organized in the document as follows: Section 2.0--Summary listing of product specifications at each major sub-system interface. Section 3.0--Summary description providing guidance as to how specifications are complied with by equipment design or processing within a major

  6. Snf1 Phosphorylates Adenylate Cyclase and Negatively Regulates Protein Kinase A-dependent Transcription in Saccharomyces cerevisiae.

    Science.gov (United States)

    Nicastro, Raffaele; Tripodi, Farida; Gaggini, Marco; Castoldi, Andrea; Reghellin, Veronica; Nonnis, Simona; Tedeschi, Gabriella; Coccetti, Paola

    2015-10-09

    In eukaryotes, nutrient availability and metabolism are coordinated by sensing mechanisms and signaling pathways, which influence a broad set of cellular functions such as transcription and metabolic pathways to match environmental conditions. In yeast, PKA is activated in the presence of high glucose concentrations, favoring fast nutrient utilization, shutting down stress responses, and boosting growth. On the contrary, Snf1/AMPK is activated in the presence of low glucose or alternative carbon sources, thus promoting an energy saving program through transcriptional activation and phosphorylation of metabolic enzymes. The PKA and Snf1/AMPK pathways share common downstream targets. Moreover, PKA has been reported to negatively influence the activation of Snf1/AMPK. We report a new cross-talk mechanism with a Snf1-dependent regulation of the PKA pathway. We show that Snf1 and adenylate cyclase (Cyr1) interact in a nutrient-independent manner. Moreover, we identify Cyr1 as a Snf1 substrate and show that Snf1 activation state influences Cyr1 phosphorylation pattern, cAMP intracellular levels, and PKA-dependent transcription. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Glucose de-repression by yeast AMP-activated protein kinase SNF1 is controlled via at least two independent steps.

    Science.gov (United States)

    García-Salcedo, Raúl; Lubitz, Timo; Beltran, Gemma; Elbing, Karin; Tian, Ye; Frey, Simone; Wolkenhauer, Olaf; Krantz, Marcus; Klipp, Edda; Hohmann, Stefan

    2014-04-01

    The AMP-activated protein kinase, AMPK, controls energy homeostasis in eukaryotic cells but little is known about the mechanisms governing the dynamics of its activation/deactivation. The yeast AMPK, SNF1, is activated in response to glucose depletion and mediates glucose de-repression by inactivating the transcriptional repressor Mig1. Here we show that overexpression of the Snf1-activating kinase Sak1 results, in the presence of glucose, in constitutive Snf1 activation without alleviating glucose repression. Co-overexpression of the regulatory subunit Reg1 of the Glc-Reg1 phosphatase complex partly restores glucose regulation of Snf1. We generated a set of 24 kinetic mathematical models based on dynamic data of Snf1 pathway activation and deactivation. The models that reproduced our experimental observations best featured (a) glucose regulation of both Snf1 phosphorylation and dephosphorylation, (b) determination of the Mig1 phosphorylation status in the absence of glucose by Snf1 activity only and (c) a regulatory step directing active Snf1 to Mig1 under glucose limitation. Hence it appears that glucose de-repression via Snf1-Mig1 is regulated by glucose via at least two independent steps: the control of activation of the Snf1 kinase and directing active Snf1 to inactivating its target Mig1. © 2014 FEBS.

  8. Uncanistered Spent Nuclear fuel Disposal Container System Description Document

    International Nuclear Information System (INIS)

    Pettit, N. E.

    2001-01-01

    The Uncanistered Spent Nuclear Fuel (SNF) Disposal Container System supports the confinement and isolation of waste within the Engineered Barrier System of the Monitored Geologic Repository (MGR). Disposal containers are loaded with intact uncanistered assemblies and/or individually canistered SNF assemblies and sealed in the surface waste handling facilities, transferred to the underground through the access drifts, and emplaced in emplacement drifts. The Uncanistered SNF Disposal Container provides long-term confinement of the commercial SNF placed inside, and withstands the loading, transfer, emplacement, and retrieval loads and environments. The Uncanistered SNF Disposal Container System provides containment of waste for a designated period of time, and limits radionuclide release. The disposal container maintains the waste in a designated configuration, withstands maximum handling and rockfall loads, limits the individual SNF assembly temperatures after emplacement, limits the introduction of moderator into the disposal container during the criticality control period, resists corrosion in the expected handling and repository environments, and provides containment of waste in the event of an accident

  9. A User's Guide to the SNF ampersand INEL EIS

    International Nuclear Information System (INIS)

    1995-01-01

    This User's Guide is intended to help you find information in the SNF and INEL EIS (that's short for US Department of Energy Programmatic Spent Nuclear Fuel Management and Idaho National Engineering Laboratory Environmental Restoration and Waste Management Programs Final Environmental Impact Statement). The first section of this Guide gives you a brief overview of the SNF ampersand INEL EIS., The second section is organized to help you find specific information in the Environmental Impact Statement -- whether you're interested in a management alternative, a particular site (such as Hanford), or a discipline (such as land use or water quality)

  10. Amino acid residues involved in ligand preference of the Snf3 transporter-like sensor in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Dietvorst, J.; Karhumaa, Kaisa; Kielland-Brandt, Morten

    2010-01-01

    /preferences of Snf3. The ability of cells to sense sugars in vivo was monitored by following the degradation of the Mth1 protein, :ill earl., event ill the signal pathway. Our study reveals that Snf3. ill addition to glucose. also senses fructose and mannose, as well as the glucose analogues 2-deoxyglucose, 3-O......-methylglucoside and 6-deoxyglucose. The signalling proficiency of a non-phosphorylatable analogue strongly supports the notion that sensing through Snf3 does not require sugar phosphorylation. Sequence comparisons of Snf3 to glucose transporters indicated amino acid residues possibly involved in sensing of sugars other...... than glucose. By site-specific mutagenesis of the structural gene, roles of specific residues in Snf3 could he established. Change of isoleucine-374 to valine ill transmembrane segment 7 of Snf3 partially abolished sensing of fructose mannose. while mutagenesis causing it change of phenylalanine-462 (4...

  11. Wongabel Rhabdovirus Accessory Protein U3 Targets the SWI/SNF Chromatin Remodeling Complex

    Science.gov (United States)

    Joubert, D. Albert; Rodriguez-Andres, Julio; Monaghan, Paul; Cummins, Michelle; McKinstry, William J.; Paradkar, Prasad N.; Moseley, Gregory W.

    2014-01-01

    ABSTRACT Wongabel virus (WONV) is an arthropod-borne rhabdovirus that infects birds. It is one of the growing array of rhabdoviruses with complex genomes that encode multiple accessory proteins of unknown function. In addition to the five canonical rhabdovirus structural protein genes (N, P, M, G, and L), the 13.2-kb negative-sense single-stranded RNA (ssRNA) WONV genome contains five uncharacterized accessory genes, one overlapping the N gene (Nx or U4), three located between the P and M genes (U1 to U3), and a fifth one overlapping the G gene (Gx or U5). Here we show that WONV U3 is expressed during infection in insect and mammalian cells and is required for efficient viral replication. A yeast two-hybrid screen against a mosquito cell cDNA library identified that WONV U3 interacts with the 83-amino-acid (aa) C-terminal domain of SNF5, a component of the SWI/SNF chromatin remodeling complex. The interaction was confirmed by affinity chromatography, and nuclear colocalization was established by confocal microscopy. Gene expression studies showed that SNF5 transcripts are upregulated during infection of mosquito cells with WONV, as well as West Nile virus (Flaviviridae) and bovine ephemeral fever virus (Rhabdoviridae), and that SNF5 knockdown results in increased WONV replication. WONV U3 also inhibits SNF5-regulated expression of the cytokine gene CSF1. The data suggest that WONV U3 targets the SWI/SNF complex to block the host response to infection. IMPORTANCE The rhabdoviruses comprise a large family of RNA viruses infecting plants, vertebrates, and invertebrates. In addition to the major structural proteins (N, P, M, G, and L), many rhabdoviruses encode a diverse array of accessory proteins of largely unknown function. Understanding the role of these proteins may reveal much about host-pathogen interactions in infected cells. Here we examine accessory protein U3 of Wongabel virus, an arthropod-borne rhabdovirus that infects birds. We show that U3 enters the

  12. Differential Roles of the Glycogen-Binding Domains of β Subunits in Regulation of the Snf1 Kinase Complex▿

    Science.gov (United States)

    Mangat, Simmanjeet; Chandrashekarappa, Dakshayini; McCartney, Rhonda R.; Elbing, Karin; Schmidt, Martin C.

    2010-01-01

    Members of the AMP-activated protein kinase family, including the Snf1 kinase of Saccharomyces cerevisiae, are activated under conditions of nutrient stress. AMP-activated protein kinases are heterotrimeric complexes composed of a catalytic α subunit and regulatory β and γ subunits. In this study, the role of the β subunits in the regulation of Snf1 activity was examined. Yeasts express three isoforms of the AMP-activated protein kinase consisting of Snf1 (α), Snf4 (γ), and one of three alternative β subunits, either Sip1, Sip2, or Gal83. The Gal83 isoform of the Snf1 complex is the most abundant and was analyzed in the greatest detail. All three β subunits contain a conserved domain referred to as the glycogen-binding domain. The deletion of this domain from Gal83 results in a deregulation of the Snf1 kinase, as judged by a constitutive activity independent of glucose availability. In contrast, the deletion of this homologous domain from the Sip1 and Sip2 subunits had little effect on Snf1 kinase regulation. Therefore, the different Snf1 kinase isoforms are regulated through distinct mechanisms, which may contribute to their specialized roles in different stress response pathways. In addition, the β subunits are subjected to phosphorylation. The responsible kinases were identified as being Snf1 and casein kinase II. The significance of the phosphorylation is unclear since the deletion of the region containing the phosphorylation sites in Gal83 had little effect on the regulation of Snf1 in response to glucose limitation. PMID:19897735

  13. Differential roles of the glycogen-binding domains of beta subunits in regulation of the Snf1 kinase complex.

    Science.gov (United States)

    Mangat, Simmanjeet; Chandrashekarappa, Dakshayini; McCartney, Rhonda R; Elbing, Karin; Schmidt, Martin C

    2010-01-01

    Members of the AMP-activated protein kinase family, including the Snf1 kinase of Saccharomyces cerevisiae, are activated under conditions of nutrient stress. AMP-activated protein kinases are heterotrimeric complexes composed of a catalytic alpha subunit and regulatory beta and gamma subunits. In this study, the role of the beta subunits in the regulation of Snf1 activity was examined. Yeasts express three isoforms of the AMP-activated protein kinase consisting of Snf1 (alpha), Snf4 (gamma), and one of three alternative beta subunits, either Sip1, Sip2, or Gal83. The Gal83 isoform of the Snf1 complex is the most abundant and was analyzed in the greatest detail. All three beta subunits contain a conserved domain referred to as the glycogen-binding domain. The deletion of this domain from Gal83 results in a deregulation of the Snf1 kinase, as judged by a constitutive activity independent of glucose availability. In contrast, the deletion of this homologous domain from the Sip1 and Sip2 subunits had little effect on Snf1 kinase regulation. Therefore, the different Snf1 kinase isoforms are regulated through distinct mechanisms, which may contribute to their specialized roles in different stress response pathways. In addition, the beta subunits are subjected to phosphorylation. The responsible kinases were identified as being Snf1 and casein kinase II. The significance of the phosphorylation is unclear since the deletion of the region containing the phosphorylation sites in Gal83 had little effect on the regulation of Snf1 in response to glucose limitation.

  14. SNF project engineering process improvement plan

    International Nuclear Information System (INIS)

    DESAI, S.P.

    1999-01-01

    This Engineering Process Improvement Plan documents the activities and plans to be taken by the SNF Project to support its engineering process and to produce a consolidated set of engineering procedures that are fully compliant with the requirements of HNF-PRO-1819. All new procedures will be issued and implemented by September 30, 1999

  15. DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity.

    Science.gov (United States)

    Riedel, Christian G; Dowen, Robert H; Lourenco, Guinevere F; Kirienko, Natalia V; Heimbucher, Thomas; West, Jason A; Bowman, Sarah K; Kingston, Robert E; Dillin, Andrew; Asara, John M; Ruvkun, Gary

    2013-05-01

    Organisms are constantly challenged by stresses and privations and require adaptive responses for their survival. The forkhead box O (FOXO) transcription factor DAF-16 (hereafter referred to as DAF-16/FOXO) is a central nexus in these responses, but despite its importance little is known about how it regulates its target genes. Proteomic identification of DAF-16/FOXO-binding partners in Caenorhabditis elegans and their subsequent functional evaluation by RNA interference revealed several candidate DAF-16/FOXO cofactors, most notably the chromatin remodeller SWI/SNF. DAF-16/FOXO and SWI/SNF form a complex and globally co-localize at DAF-16/FOXO target promoters. We show that specifically for gene activation, DAF-16/FOXO depends on SWI/SNF, facilitating SWI/SNF recruitment to target promoters, to activate transcription by presumed remodelling of local chromatin. For the animal, this translates into an essential role for SWI/SNF in DAF-16/FOXO-mediated processes, in particular dauer formation, stress resistance and the promotion of longevity. Thus, we give insight into the mechanisms of DAF-16/FOXO-mediated transcriptional regulation and establish a critical link between ATP-dependent chromatin remodelling and lifespan regulation.

  16. Human Error Prediction and Countermeasures based on CREAM in Loading and Storage Phase of Spent Nuclear Fuel (SNF)

    International Nuclear Information System (INIS)

    Kim, Jae San; Kim, Min Su; Jo, Seong Youn

    2007-01-01

    With the steady demands for nuclear power energy in Korea, the amount of accumulated SNF has inevitably increased year by year. Thus far, SNF has been on-site transported from one unit to a nearby unit or an on-site dry storage facility. In the near future, as the amount of SNF generated approaches the capacity of these facilities, a percentage of it will be transported to another SNF storage facility. In the process of transporting SNF, human interactions involve inspecting and preparing the cask and spent fuel, loading the cask, transferring the cask and storage or monitoring the cask, etc. So, human actions play a significant role in SNF transportation. In analyzing incidents that have occurred during transport operations, several recent studies have indicated that 'human error' is a primary cause. Therefore, the objectives of this study are to predict and identify possible human errors during the loading and storage of SNF. Furthermore, after evaluating human error for each process, countermeasures to minimize human error are deduced

  17. Role of Snf3 in glucose homeostasis of Saccharomyces cerevisiae (review)

    DEFF Research Database (Denmark)

    Kielland-Brandt, Morten

    signal pathways in directions opposite to those caused by extracellular nutrients (6,7), a phenomenon predicted to contribute to intracellular nutrient homeostasis. Although significant, the influence of intracellular leucine on signaling from Ssy1 is relatively modest (6), whereas the conditions...... with enhanced intracellular glucose concentrations (7) caused a strong decrease in signaling from Snf3, suggesting an important role of Snf3 in intracellular glucose homeostasis. Strategies for studies of this role will be discussed....

  18. Market driven strategy for acquisition of waste acceptance and transportation services for commercial spent fuel in the United States

    International Nuclear Information System (INIS)

    Lemeshewky, W.; Macaluso, C.; Smith, P.; Teer, B.

    1998-05-01

    The Department of Energy has the responsibility for the shipment of spent nuclear fuel (SNF) from commercial reactors to a Federal facility for storage and/or disposal. DOE has developed a strategy for a market driven approach for the acquisition of transportation services and equipment which will maximize the participation of private industry. To implement this strategy, DOE is planning to issue a Request for Proposal (RFP) for the provision of the required services and equipment to accept SNF from the utilities and transport the SNF to a Federal facility. The paper discusses this strategy and describes the RFP

  19. DAF-16/FOXO employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

    Science.gov (United States)

    Riedel, Christian G.; Dowen, Robert H.; Lourenco, Guinevere F.; Kirienko, Natalia V.; Heimbucher, Thomas; West, Jason A.; Bowman, Sarah K.; Kingston, Robert E.; Dillin, Andrew; Asara, John M.; Ruvkun, Gary

    2013-01-01

    Organisms are constantly challenged by stresses and privations and require adaptive responses for their survival. The transcription factor DAF-16/FOXO is central nexus in these responses, but despite its importance little is known about how it regulates its target genes. Proteomic identification of DAF-16/FOXO binding partners in Caenorhabditis elegans and their subsequent functional evaluation by RNA interference (RNAi) revealed several candidate DAF-16/FOXO cofactors, most notably the chromatin remodeller SWI/SNF. DAF-16/FOXO and SWI/SNF form a complex and globally colocalize at DAF-16/FOXO target promoters. We show that specifically for gene-activation, DAF-16/FOXO depends on SWI/SNF, facilitating SWI/SNF recruitment to target promoters, in order to activate transcription by presumed remodelling of local chromatin. For the animal, this translates into an essential role of SWI/SNF for DAF-16/FOXO-mediated processes, i.e. dauer formation, stress resistance, and the promotion of longevity. Thus we give insight into the mechanisms of DAF-16/FOXO-mediated transcriptional regulation and establish a critical link between ATP-dependent chromatin remodelling and lifespan regulation. PMID:23604319

  20. A model for the release, dispersion and environmental impact of a postulated reactor accident from a submerged commercial nuclear power plant

    Science.gov (United States)

    Bertch, Timothy Creston

    1998-12-01

    Nuclear power plants are inherently suitable for submerged applications and could provide power to the shore power grid or support future underwater applications. The technology exists today and the construction of a submerged commercial nuclear power plant may become desirable. A submerged reactor is safer to humans because the infinite supply of water for heat removal, particulate retention in the water column, sedimentation to the ocean floor and inherent shielding of the aquatic environment would significantly mitigate the effects of a reactor accident. A better understanding of reactor operation in this new environment is required to quantify the radioecological impact and to determine the suitability of this concept. The impact of release to the environment from a severe reactor accident is a new aspect of the field of marine radioecology. Current efforts have been centered on radioecological impacts of nuclear waste disposal, nuclear weapons testing fallout and shore nuclear plant discharges. This dissertation examines the environmental impact of a severe reactor accident in a submerged commercial nuclear power plant, modeling a postulated site on the Atlantic continental shelf adjacent to the United States. This effort models the effects of geography, decay, particle transport/dispersion, bioaccumulation and elimination with associated dose commitment. The use of a source term equivalent to the release from Chernobyl allows comparison between the impacts of that accident and the postulated submerged commercial reactor plant accident. All input parameters are evaluated using sensitivity analysis. The effect of the release on marine biota is determined. Study of the pathways to humans from gaseous radionuclides, consumption of contaminated marine biota and direct exposure as contaminated water reaches the shoreline is conducted. The model developed by this effort predicts a significant mitigation of the radioecological impact of the reactor accident release

  1. Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK

    DEFF Research Database (Denmark)

    Nicastro, Raffaele; Tripodi, Farida; Guzzi, Cinzia

    2015-01-01

    when grown with glucose excess. We show that loss of Snf1 in cells growing in 2% glucose induces an extensive transcriptional reprogramming, enhances glycolytic activity, fatty acid accumulation and reliance on amino acid utilization for growth. Strikingly, we demonstrate that Snf1/AMPK-deficient cells...... remodel their metabolism fueling mitochondria and show glucose and amino acids addiction, a typical hallmark of cancer cells....

  2. Spent Nuclear Fuel (SNF) Project Design Verification and Validation Process

    International Nuclear Information System (INIS)

    OLGUIN, L.J.

    2000-01-01

    This document provides a description of design verification and validation activities implemented by the Spent Nuclear Fuel (SNF) Project. During the execution of early design verification, a management assessment (Bergman, 1999) and external assessments on configuration management (Augustenburg, 1999) and testing (Loscoe, 2000) were conducted and identified potential uncertainties in the verification process. This led the SNF Chief Engineer to implement corrective actions to improve process and design products. This included Design Verification Reports (DVRs) for each subproject, validation assessments for testing, and verification of the safety function of systems and components identified in the Safety Equipment List to ensure that the design outputs were compliant with the SNF Technical Requirements. Although some activities are still in progress, the results of the DVR and associated validation assessments indicate that Project requirements for design verification are being effectively implemented. These results have been documented in subproject-specific technical documents (Table 2). Identified punch-list items are being dispositioned by the Project. As these remaining items are closed, the technical reports (Table 2) will be revised and reissued to document the results of this work

  3. Spent Nuclear Fuel (SNF) Project Execution Plan

    International Nuclear Information System (INIS)

    LEROY, P.G.

    2000-01-01

    The Spent Nuclear Fuel (SNF) Project supports the Hanford Site Mission to cleanup the Site by providing safe, economic, environmentally sound management of Site spent nuclear fuel in a manner that reduces hazards by staging it to interim onsite storage and deactivates the 100 K Area facilities

  4. Spent Nuclear Fuel (SNF) Project Execution Plan

    Energy Technology Data Exchange (ETDEWEB)

    LEROY, P.G.

    2000-11-03

    The Spent Nuclear Fuel (SNF) Project supports the Hanford Site Mission to cleanup the Site by providing safe, economic, environmentally sound management of Site spent nuclear fuel in a manner that reduces hazards by staging it to interim onsite storage and deactivates the 100 K Area facilities.

  5. Snf2 family gene distribution in higher plant genomes reveals DRD1 expansion and diversification in the tomato genome.

    Science.gov (United States)

    Bargsten, Joachim W; Folta, Adam; Mlynárová, Ludmila; Nap, Jan-Peter

    2013-01-01

    As part of large protein complexes, Snf2 family ATPases are responsible for energy supply during chromatin remodeling, but the precise mechanism of action of many of these proteins is largely unknown. They influence many processes in plants, such as the response to environmental stress. This analysis is the first comprehensive study of Snf2 family ATPases in plants. We here present a comparative analysis of 1159 candidate plant Snf2 genes in 33 complete and annotated plant genomes, including two green algae. The number of Snf2 ATPases shows considerable variation across plant genomes (17-63 genes). The DRD1, Rad5/16 and Snf2 subfamily members occur most often. Detailed analysis of the plant-specific DRD1 subfamily in related plant genomes shows the occurrence of a complex series of evolutionary events. Notably tomato carries unexpected gene expansions of DRD1 gene members. Most of these genes are expressed in tomato, although at low levels and with distinct tissue or organ specificity. In contrast, the Snf2 subfamily genes tend to be expressed constitutively in tomato. The results underpin and extend the Snf2 subfamily classification, which could help to determine the various functional roles of Snf2 ATPases and to target environmental stress tolerance and yield in future breeding.

  6. Conception of transport cask with advanced safety, aimed at transportation and storage of spent nuclear fuel of power reactors, which meets the requirements of IAEA in terms of safety and increased stability during beyond-design-basis accidents and acts of terrorism

    International Nuclear Information System (INIS)

    Il'kaev, R.I.; Matveev, V.Z.; Morenko, A.I.; Shapovalov, V.I.; Semenov, A.G.; Sergeyev, V.M.; Orlov, V.K.; Shatalov, V.V.; Gotovchikov, V.T.; Seredenko, V.A.; Haire, Jonathan M.; Forsberg, C.W.

    2004-01-01

    The report is devoted to the problem of creation of a new generation of multi-purpose universal transport cask with advanced safety, aimed at transportation and storage of spent nuclear fuel (SNF) of power reactors, which meets all requirements of IAEA in terms of safety and increased stability during beyond-design-basis accidents and acts of terrorism. Meeting all IAEA requirements in terms of safety both in normal operation conditions and accidents, as well as increased stability of transport cask (TC) with SNF under the conditions of beyond-design-basis accidents and acts of terrorism has been achieved in the design of multi-purpose universal TC due to the use of DU (depleted uranium) in it. At that, it is suggested to use DU in TC, which acts as effective gamma shield and constructional material in the form of both metallic depleted uranium and metal-ceramic mixture (cermet), based on stainless or carbon steel and DU dioxide. The metal in the cermet is chosen to optimize cask performance. The use of DU in the design of multi-purpose universal TC enables getting maximum load of the container for spent nuclear fuel when meeting IAEA requirements in terms of safety and providing increased stability of the container with SNF under conditions of beyond-design-basis accident and acts of terrorism

  7. Conception of transport cask with advanced safety, aimed at transportation and storage of spent nuclear fuel of power reactors, which meets the requirements of IAEA in terms of safety and increased stability during beyond-design-basis accidents and acts of terrorism

    Energy Technology Data Exchange (ETDEWEB)

    Il' kaev, R.I.; Matveev, V.Z.; Morenko, A.I.; Shapovalov, V.I. [Russian Federal Nuclear Center - All-Russian Research Inst. of Experimental Physics, Sarov (Russian Federation); Semenov, A.G.; Sergeyev, V.M.; Orlov, V.K. [All-Russian Research Inst. of Inorganic Materials, Moscow (Russian Federation); Shatalov, V.V.; Gotovchikov, V.T.; Seredenko, V.A. [All-Russian Research Inst. of Applied Chemistry, Moscow (Russian Federation); Haire, Jonathan M.; Forsberg, C.W. [Oak Ridge National Lab., Oak Ridge (United States)

    2004-07-01

    The report is devoted to the problem of creation of a new generation of multi-purpose universal transport cask with advanced safety, aimed at transportation and storage of spent nuclear fuel (SNF) of power reactors, which meets all requirements of IAEA in terms of safety and increased stability during beyond-design-basis accidents and acts of terrorism. Meeting all IAEA requirements in terms of safety both in normal operation conditions and accidents, as well as increased stability of transport cask (TC) with SNF under the conditions of beyond-design-basis accidents and acts of terrorism has been achieved in the design of multi-purpose universal TC due to the use of DU (depleted uranium) in it. At that, it is suggested to use DU in TC, which acts as effective gamma shield and constructional material in the form of both metallic depleted uranium and metal-ceramic mixture (cermet), based on stainless or carbon steel and DU dioxide. The metal in the cermet is chosen to optimize cask performance. The use of DU in the design of multi-purpose universal TC enables getting maximum load of the container for spent nuclear fuel when meeting IAEA requirements in terms of safety and providing increased stability of the container with SNF under conditions of beyond-design-basis accident and acts of terrorism.

  8. Security preparation for receipt of SNF from the FRR to the INEEL

    International Nuclear Information System (INIS)

    Dahlquist, R.L.

    1997-01-01

    This paper reports the key security related activities associated with the FRR shipment. Starting with transportation of the SNF in the country of origin to the final destination at the INEEL. Methodology for compliance will be addressed. The graded approach and a three step system will be explained. This paper will be used as part of the planning to support the FRR Project for returning the Asia and European SNF back to the US

  9. Preparation for the Recovery of Spent Nuclear Fuel (SNF) at Andreeva Bay, North West Russia - 13309

    International Nuclear Information System (INIS)

    Field, D.; McAtamney, N.

    2013-01-01

    Andreeva Bay is located near Murmansk in the Russian Federation close to the Norwegian border. The ex-naval site was used to de-fuel nuclear-powered submarines and icebreakers during the Cold War. Approximately 22,000 fuel assemblies remain in three Dry Storage Units (DSUs) which means that Andreeva Bay has one of the largest stockpiles of highly enriched spent nuclear fuel (SNF) in the world. The high contamination and deteriorating condition of the SNF canisters has made improvements to the management of the SNF a high priority for the international community for safety, security and environmental reasons. International Donors have, since 2002, provided support to projects at Andreeva concerned with improving the management of the SNF. This long-term programme of work has been coordinated between the International Donors and responsible bodies within the Russian Federation. Options for the safe and secure management of SNF at Andreeva Bay were considered in 2004 and developed by a number of Russian Institutes with international participation. This consisted of site investigations, surveys and studies to understand the technical challenges. A principal agreement was reached that the SNF would be removed from the site altogether and transported to Russia's reprocessing facility at Mayak in the Urals. The analytical studies provided the information necessary to develop the construction plan for the site. Following design and regulatory processes, stakeholders endorsed the technical solution in April 2007. This detailed the processes, facilities and equipment required to safely remove the SNF and identified other site services and support facilities required on the site. Implementation of this strategy is now well underway with the facilities in various states of construction. Physical works have been performed to address the most urgent tasks including weather protection over one of the DSUs, installation of shielding over the cells, provision of radiation

  10. Preparation for the Recovery of Spent Nuclear Fuel (SNF) at Andreeva Bay, North West Russia - 13309

    Energy Technology Data Exchange (ETDEWEB)

    Field, D.; McAtamney, N. [Nuvia Limited (United Kingdom)

    2013-07-01

    Andreeva Bay is located near Murmansk in the Russian Federation close to the Norwegian border. The ex-naval site was used to de-fuel nuclear-powered submarines and icebreakers during the Cold War. Approximately 22,000 fuel assemblies remain in three Dry Storage Units (DSUs) which means that Andreeva Bay has one of the largest stockpiles of highly enriched spent nuclear fuel (SNF) in the world. The high contamination and deteriorating condition of the SNF canisters has made improvements to the management of the SNF a high priority for the international community for safety, security and environmental reasons. International Donors have, since 2002, provided support to projects at Andreeva concerned with improving the management of the SNF. This long-term programme of work has been coordinated between the International Donors and responsible bodies within the Russian Federation. Options for the safe and secure management of SNF at Andreeva Bay were considered in 2004 and developed by a number of Russian Institutes with international participation. This consisted of site investigations, surveys and studies to understand the technical challenges. A principal agreement was reached that the SNF would be removed from the site altogether and transported to Russia's reprocessing facility at Mayak in the Urals. The analytical studies provided the information necessary to develop the construction plan for the site. Following design and regulatory processes, stakeholders endorsed the technical solution in April 2007. This detailed the processes, facilities and equipment required to safely remove the SNF and identified other site services and support facilities required on the site. Implementation of this strategy is now well underway with the facilities in various states of construction. Physical works have been performed to address the most urgent tasks including weather protection over one of the DSUs, installation of shielding over the cells, provision of radiation

  11. Causes and risk factors for fatal accidents in non-commercial twin engine piston general aviation aircraft.

    Science.gov (United States)

    Boyd, Douglas D

    2015-04-01

    Accidents in twin-engine aircraft carry a higher risk of fatality compared with single engine aircraft and constitute 9% of all general aviation accidents. The different flight profile (higher airspeed, service ceiling, increased fuel load, and aircraft yaw in engine failure) may make comparable studies on single-engine aircraft accident causes less relevant. The objective of this study was to identify the accident causes for non-commercial operations in twin engine aircraft. A NTSB accident database query for accidents in twin piston engine airplanes of 4-8 seat capacity with a maximum certified weight of 3000-8000lbs. operating under 14CFR Part 91 for the period spanning 2002 and 2012 returned 376 accidents. Accident causes and contributing factors were as per the NTSB final report categories. Total annual flight hour data for the twin engine piston aircraft fleet were obtained from the FAA. Statistical analyses employed Chi Square, Fisher's Exact and logistic regression analysis. Neither the combined fatal/non-fatal accident nor the fatal accident rate declined over the period spanning 2002-2012. Under visual weather conditions, the largest number, n=27, (27%) of fatal accidents was attributed to malfunction with a failure to follow single engine procedures representing the most common contributing factor. In degraded visibility, poor instrument approach procedures resulted in the greatest proportion of fatal crashes. Encountering thunderstorms was the most lethal of all accident causes with all occupants sustaining fatal injuries. At night, a failure to maintain obstacle/terrain clearance was the most common accident cause leading to 36% of fatal crashes. The results of logistic regression showed that operations at night (OR 3.7), off airport landings (OR 14.8) and post-impact fire (OR 7.2) all carried an excess risk of a fatal flight. This study indicates training areas that should receive increased emphasis for twin-engine training/recency. First, increased

  12. ACCIDENT ANALYSES & CONTROL OPTIONS IN SUPPORT OF THE SLUDGE WATER SYSTEM SAFETY ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    WILLIAMS, J.C.

    2003-11-15

    This report documents the accident analyses and nuclear safety control options for use in Revision 7 of HNF-SD-WM-SAR-062, ''K Basins Safety Analysis Report'' and Revision 4 of HNF-SD-SNF-TSR-001, ''Technical Safety Requirements - 100 KE and 100 KW Fuel Storage Basins''. These documents will define the authorization basis for Sludge Water System (SWS) operations. This report follows the guidance of DOE-STD-3009-94, ''Preparation Guide for US. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports'', for calculating onsite and offsite consequences. The accident analysis summary is shown in Table ES-1 below. While this document describes and discusses potential control options to either mitigate or prevent the accidents discussed herein, it should be made clear that the final control selection for any accident is determined and presented in HNF-SD-WM-SAR-062.

  13. Snf2 family gene distribution in higher plant genomes reveals DRD1 expansion and diversification in the tomato genome.

    Directory of Open Access Journals (Sweden)

    Joachim W Bargsten

    Full Text Available As part of large protein complexes, Snf2 family ATPases are responsible for energy supply during chromatin remodeling, but the precise mechanism of action of many of these proteins is largely unknown. They influence many processes in plants, such as the response to environmental stress. This analysis is the first comprehensive study of Snf2 family ATPases in plants. We here present a comparative analysis of 1159 candidate plant Snf2 genes in 33 complete and annotated plant genomes, including two green algae. The number of Snf2 ATPases shows considerable variation across plant genomes (17-63 genes. The DRD1, Rad5/16 and Snf2 subfamily members occur most often. Detailed analysis of the plant-specific DRD1 subfamily in related plant genomes shows the occurrence of a complex series of evolutionary events. Notably tomato carries unexpected gene expansions of DRD1 gene members. Most of these genes are expressed in tomato, although at low levels and with distinct tissue or organ specificity. In contrast, the Snf2 subfamily genes tend to be expressed constitutively in tomato. The results underpin and extend the Snf2 subfamily classification, which could help to determine the various functional roles of Snf2 ATPases and to target environmental stress tolerance and yield in future breeding.

  14. Duo_2-Steel cermet manufacturing technology for PWR Spent Nuclear Fuel (SNF) casks

    International Nuclear Information System (INIS)

    Siti Alimah; Budiarto

    2005-01-01

    Assessment of DUO_2-Steel cermet manufacturing technology for PWR SNF casks has been done. DUO_2-Steel cermet consisting of DUO_2 particulates and other particulates, embedded in a steel matrix. Cermet SNF casks have the potential for superior performance compared with casks constructed of other materials. The addition of DUO_2 ceramic particulates can increase SNF cask capacity, improve of repository performance and disposal of excess depleted uranium as potential waste. Two sets of cermet manufacturing technologies are casting and powder metallurgy. Three casting methods are infusion casting, traditional casting and centrifugal casting. While for powder metallurgy methods there are traditional method and new method. DUO_2-Steel cermet have traditionally been produced by powder metallurgy methods. The production of a cask, however, presents special requirements: the manufacture of an annular object with weights up to 100 tons, and methods are being not to manufacture a cermet of this size and geometry. A new powder metallurgy method, is a method for manufacturing cermet for PWR SNF cask. This powder metallurgy techniques have potentials low costs and provides greater freedom In the design of the cermet cask by allowing variable cermet properties. (author)

  15. Technical, economical and legal aspects of repatriation of Russian-origin research reactor SNF to Russia

    International Nuclear Information System (INIS)

    Smirnov, A.; Kanashov, B.; Efarov, S.; Lebedev, A.; Kolupaev, D.

    2005-01-01

    The aim of the report is to find some principal decisions to implement an Agreement between the Governments of the Russian Federation and the USA on repatriation of the research reactor spent nuclear fuel (RR SNF) to the Russian Federation. The report presents some ideas and approaches to the transportation of the Russian-origin RR SNF from the technical, economical and legal viewpoints. The report summarizes the Russian experience and possibilities to fulfill the program under the Agreement. Some decisions are proposed related to application of the international transportation experience and the most advanced technologies for the RR SNF handling. At present, there is no any unified SNF transportation technology that is capable to implement the transportation program schedule set by the Agreement. The decision is in the comprehensive approach as well as in the development of mobile and flexible schemes and in implementation of parallel and combined shipments. (author)

  16. Security preparation for receipt of SNF from the FRR to the INEEL

    International Nuclear Information System (INIS)

    Dahlquist, Rhonda L.

    1997-01-01

    This paper reports the key security-related activities associated with the Foreign Research Reactors (FRR) shipment. Starting with Transportation of the SNF in the country of origin to the final destination at the INEEL. Methodology for compliance will be addressed. The graded approach and a three-step system will be explained. This paper will be used as part of the planning to support the FRR Project for returning the Asia and European SNF back to the United States. (author)

  17. Spent Nuclear Fuel (SNF) Bounding Drop Support Calculations

    International Nuclear Information System (INIS)

    CHENAULT, D.M.

    1999-01-01

    This report evaluates different drop heights, concrete and other impact media to which the transport package and/or the MCO is dropped. A prediction method is derived for estimating the resultant impact factor for determining the bounding drop case for the SNF Project

  18. Database on aircraft accidents

    International Nuclear Information System (INIS)

    Nishio, Masahide; Koriyama, Tamio

    2012-09-01

    The Reactor Safety Subcommittee in the Nuclear Safety and Preservation Committee published the report 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' as the standard method for evaluating probability of aircraft crash into nuclear reactor facilities in July 2002. In response to the report, Japan Nuclear Energy Safety Organization has been collecting open information on aircraft accidents of commercial airplanes, self-defense force (SDF) airplanes and US force airplanes every year since 2003, sorting out them and developing the database of aircraft accidents for latest 20 years to evaluate probability of aircraft crash into nuclear reactor facilities. This year, the database was revised by adding aircraft accidents in 2010 to the existing database and deleting aircraft accidents in 1991 from it, resulting in development of the revised 2011 database for latest 20 years from 1991 to 2010. Furthermore, the flight information on commercial aircrafts was also collected to develop the flight database for latest 20 years from 1991 to 2010 to evaluate probability of aircraft crash into reactor facilities. The method for developing the database of aircraft accidents to evaluate probability of aircraft crash into reactor facilities is based on the report 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' described above. The 2011 revised database for latest 20 years from 1991 to 2010 shows the followings. The trend of the 2011 database changes little as compared to the last year's one. (1) The data of commercial aircraft accidents is based on 'Aircraft accident investigation reports of Japan transport safety board' of Ministry of Land, Infrastructure, Transport and Tourism. 4 large fixed-wing aircraft accidents, 58 small fixed-wing aircraft accidents, 5 large bladed aircraft accidents and 114 small bladed aircraft accidents occurred. The relevant accidents for evaluating

  19. Database on aircraft accidents

    International Nuclear Information System (INIS)

    Nishio, Masahide; Koriyama, Tamio

    2013-11-01

    The Reactor Safety Subcommittee in the Nuclear Safety and Preservation Committee published 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' as the standard method for evaluating probability of aircraft crash into nuclear reactor facilities in July 2002. In response to this issue, Japan Nuclear Energy Safety Organization has been collecting open information on aircraft accidents of commercial airplanes, self-defense force (SDF) airplanes and US force airplanes every year since 2003, sorting out them and developing the database of aircraft accidents for the latest 20 years to evaluate probability of aircraft crash into nuclear reactor facilities. In this report the database was revised by adding aircraft accidents in 2011 to the existing database and deleting aircraft accidents in 1991 from it, resulting in development of the revised 2012 database for the latest 20 years from 1992 to 2011. Furthermore, the flight information on commercial aircrafts was also collected to develop the flight database for the latest 20 years from 1992 to 2011 to evaluate probability of aircraft crash into reactor facilities. The method for developing the database of aircraft accidents to evaluate probability of aircraft crash into reactor facilities is based on the report 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' described above. The 2012 revised database for the latest 20 years from 1992 to 2011 shows the followings. The trend of the 2012 database changes little as compared to the last year's report. (1) The data of commercial aircraft accidents is based on 'Aircraft accident investigation reports of Japan transport safety board' of Ministry of Land, Infrastructure, Transport and Tourism. The number of commercial aircraft accidents is 4 for large fixed-wing aircraft, 58 for small fixed-wing aircraft, 5 for large bladed aircraft and 99 for small bladed aircraft. The relevant accidents

  20. Criticality Potential of Waste Packages Containing DOE SNF Affected by Igneous Intrusion

    International Nuclear Information System (INIS)

    D.S. Kimball; C.E. Sanders

    2006-01-01

    The Department of Energy (DOE) is currently preparing an application to submit to the U.S. Nuclear Regulatory Commission for a construction authorization for a monitored geologic repository. The repository will contain spent nuclear fuel (SNF) and defense high-level waste (DHLW) in waste packages placed in underground tunnels, or drifts. The primary objective of this paper is to perform a criticality analysis for waste packages containing DOE SNF affected by a disruptive igneous intrusion event in the emplacement drifts. The waste packages feature one DOE SNF canister placed in the center and surrounded by five High-Level Waste (HLW) glass canisters. The effective neutron multiplication factor (k eff ) is determined for potential configurations of the waste package during and after an intrusive igneous event. Due to the complexity of the potential scenarios following an igneous intrusion, finding conservative and bounding configurations with respect to criticality requires some additional considerations. In particular, the geometry of a slumped and damaged waste package must be examined, drift conditions must be modeled over a range of parameters, and the chemical degradation of DOE SNF and waste package materials must be considered for the expected high temperatures. The secondary intent of this calculation is to present a method for selecting conservative and bounding configurations for a wide range of end conditions

  1. An Examination of Commercial Aviation Accidents and Incidents Related to Integrated Vehicle Health Management

    Science.gov (United States)

    Reveley, Mary S.; Briggs, Jeffrey L.; Thomas, Megan A.; Evans, Joni K.; Jones, Sharon M.

    2011-01-01

    The Integrated Vehicle Health Management (IVHM) Project is one of the four projects within the National Aeronautics and Space Administration's (NASA) Aviation Safety Program (AvSafe). The IVHM Project conducts research to develop validated tools and technologies for automated detection, diagnosis, and prognosis that enable mitigation of adverse events during flight. Adverse events include those that arise from system, subsystem, or component failure, faults, and malfunctions due to damage, degradation, or environmental hazards that occur during flight. Determining the causal factors and adverse events related to IVHM technologies will help in the formulation of research requirements and establish a list of example adverse conditions against which IVHM technologies can be evaluated. This paper documents the results of an examination of the most recent statistical/prognostic accident and incident data that is available from the Aviation Safety Information Analysis and Sharing (ASIAS) System to determine the causal factors of system/component failures and/or malfunctions in U.S. commercial aviation accidents and incidents.

  2. K Basins Spent Nuclear Fuel (SNF) Project Safety Analysis Report for Packaging (SARP) approval plan

    International Nuclear Information System (INIS)

    1995-01-01

    This document delineates the plan for preparation, review, and approval of the K Basins Spent Nuclear Fuel (SNF) Packaging Design Criteria (PDC) document and the on-site Safety Analysis Report for Packaging (SARP). The packaging addressed in these documents is used to transport SNF in a Multi- canister Overpack (MCO) configuration

  3. Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

    Science.gov (United States)

    Tsurusaki, Yoshinori; Okamoto, Nobuhiko; Ohashi, Hirofumi; Kosho, Tomoki; Imai, Yoko; Hibi-Ko, Yumiko; Kaname, Tadashi; Naritomi, Kenji; Kawame, Hiroshi; Wakui, Keiko; Fukushima, Yoshimitsu; Homma, Tomomi; Kato, Mitsuhiro; Hiraki, Yoko; Yamagata, Takanori; Yano, Shoji; Mizuno, Seiji; Sakazume, Satoru; Ishii, Takuma; Nagai, Toshiro; Shiina, Masaaki; Ogata, Kazuhiro; Ohta, Tohru; Niikawa, Norio; Miyatake, Satoko; Okada, Ippei; Mizuguchi, Takeshi; Doi, Hiroshi; Saitsu, Hirotomo; Miyake, Noriko; Matsumoto, Naomichi

    2012-03-18

    By exome sequencing, we found de novo SMARCB1 mutations in two of five individuals with typical Coffin-Siris syndrome (CSS), a rare autosomal dominant anomaly syndrome. As SMARCB1 encodes a subunit of the SWItch/Sucrose NonFermenting (SWI/SNF) complex, we screened 15 other genes encoding subunits of this complex in 23 individuals with CSS. Twenty affected individuals (87%) each had a germline mutation in one of six SWI/SNF subunit genes, including SMARCB1, SMARCA4, SMARCA2, SMARCE1, ARID1A and ARID1B.

  4. Thermal properties and phase transition in the fluoride, (NH4)3SnF7

    International Nuclear Information System (INIS)

    Kartashev, A.V.; Gorev, M.V.; Bogdanov, E.V.; Flerov, I.N.; Laptash, N.M.

    2016-01-01

    Calorimetric, dilatometric and differential thermal analysis studies were performed on (NH 4 ) 3 SnF 7 for a wide range of temperatures and pressures. Large entropy (δS 0 =22 J/mol K) and elastic deformation (δ(ΔV/V) 0 =0.89%) jumps have proven that the Pa-3↔Pm-3m phase transition is a strong first order structural transformation. A total entropy change of ΔS 0 =32.5 J/mol K is characteristic for the order–disorder phase transition, and is equal to the sum of entropy changes in the related material, (NH 4 ) 3 TiF 7 , undergoing transformation between the two cubic phases through the intermediate phases. Hydrostatic pressure decreases the stability of the high temperature Pm-3m phase in (NH 4 ) 3 SnF 7 , contrary to (NH 4 ) 3 TiF 7 , characterised by a negative baric coefficient. The effect of experimental conditions on the chemical stability of (NH 4 ) 3 SnF 7 was observed. - Graphical abstract: Strong first order structural transformation Pa-3↔Pm-3m in (NH 4 ) 3 SnF 7 is associated with very large total entropy change of ΔS 0 =32.5 J/mol K characteristic for the ordering processes and equal to the sum of entropy changes in the related (NH 4 ) 3 TiF 7 undergoing transformation between the same two cubic phases through the intermediate phases. - Highlights: • (NH 4 ) 3 SnF 7 undergoes strong first order Pa-3↔Pm-3m phase transition. • Anomalous behaviour of ΔC p and ΔV/V exists far below phase transition temperature. • Structural distortions are accompanied by huge total entropy change ΔS≈Rln50. • High pressure strongly increases the stability of Pa-3 phase in (NH 4 ) 3 SnF 7 . • Entropy of the Pa-3↔Pm-3m phase transition does not depend on pressure.

  5. Assessment results of the Indonesian TRIGA SNF to be shipped to INEEL

    International Nuclear Information System (INIS)

    Jefimoff, J.; Robb, A.K.; Wendt, K.M.; Syarip, I.; Alfa, T.

    1997-01-01

    This paper describes the Training, Research, Isotope, General Atomics (TRIGA) spent nuclear fuel (SNF) examination performed by technical personnel from the Idaho National Engineering and Environmental Laboratory (INEEL) at the Bandung and Yogyakarta research reactor facilities in Indonesia. The examination was required before the SNF would be accepted for transportation to and storage at the INEEL. This paper delineates the Initial Preparations prior to the Indonesian foreign research reactor (FRR) fuel examination. The technical basis for the examination, the TRIGA SNF Acceptance Criteria, and the physical condition required for transportation, receipt and storage of the TRIGA SNF at the INEEL is explained. In addition to the initial preparations, preparation descriptions of the Work Plan For TRIGA Fuel Examination, the Underwater Examination Equipment used, and personnel Examination Team Training are included. Finally, the Fuel Examination and Results of the aluminum and stainless steel clad TRIGA fuel examination have been summarized. Lessons learned from all the activities completed to date is provided in an addendum. The initial preparations included: (1) coordination between the INEEL, FRR or Badan Tenaga Atom Nasional (BATAN), DOE-HQ, and the US State Department and Embassy; (2) incorporating Savannah River Site (SRS) FRR experience and lessons learned; (3) collecting both FRR facility and spent fuel data, and issuing a radionuclide report (Radionuclide Mass Inventory, Activity, Decay Heat, and Dose Rate Parametric Data for TRIGA Spent Nuclear Fuels) needed for transportation and fuel acceptance at the INEEL; and (4) preexamination work at the research reactor for the fuel examination

  6. Volumes, Masses, and Surface Areas for Shippingport LWBR Spent Nuclear Fuel in a DOE SNF Canister

    International Nuclear Information System (INIS)

    J.W. Davis

    1999-01-01

    The purpose of this calculation is to estimate volumes, masses, and surface areas associated with (a) an empty Department of Energy (DOE) 18-inch diameter, 15-ft long spent nuclear fuel (SNF) canister, (b) an empty DOE 24-inch diameter, 15-ft long SNF canister, (c) Shippingport Light Water Breeder Reactor (LWBR) SNF, and (d) the internal basket structure for the 18-in. canister that has been designed specifically to accommodate Seed fuel from the Shippingport LWBR. Estimates of volumes, masses, and surface areas are needed as input to structural, thermal, geochemical, nuclear criticality, and radiation shielding calculations to ensure the viability of the proposed disposal configuration

  7. The pathway by which the yeast protein kinase Snf1p controls acquisition of sodium tolerance is different from that mediating glucose regulation.

    Science.gov (United States)

    Ye, Tian; Elbing, Karin; Hohmann, Stefan

    2008-09-01

    It recently became apparent that the highly conserved Snf1p protein kinase plays roles in controlling different cellular processes in the yeast Saccharomyces cerevisiae, in addition to its well-known function in glucose repression/derepression. We have previously reported that Snf1p together with Gis4p controls ion homeostasis by regulating expression of ENA1, which encodes the Ena1p Na(+) extrusion system. In this study we found that Snf1p is rapidly phosphorylated when cells are exposed to NaCl and this phosphorylation is required for the role of Snf1p in Na(+) tolerance. In contrast to activation by low glucose levels, the salt-induced phosphorylation of Snf1p promoted neither phosphorylation nor nuclear export of the Mig1p repressor. The mechanism that prevents Mig1p phosphorylation by active Snf1p under salt stress does not involve either hexokinase PII or the Gis4p regulator. Instead, Snf1p may mediate upregulation of ENA1 expression via the repressor Nrg1p. Activation of Snf1p in response to glucose depletion requires any of the three upstream protein kinases Sak1p, Tos3p and Elm1p, with Sak1p playing the most prominent role. The same upstream kinases were required for salt-induced Snf1p phosphorylation, and also under these conditions Sak1p played the most prominent role. Unexpectedly, however, it appears that Elm1p plays a dual role in acquisition of salt tolerance by activating Snf1p and in a presently unknown parallel pathway. Together, these results indicate that under salt stress Snf1p takes part in a different pathway from that during glucose depletion and this role is performed together as well as in parallel with its upstream kinase Elm1p. Snf1p appears to be part of a wider functional network than previously anticipated and the full complexity of this network remains to be elucidated.

  8. Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.

    Science.gov (United States)

    Otsuki, T; Furukawa, Y; Ikeda, K; Endo, H; Yamashita, T; Shinohara, A; Iwamatsu, A; Ozawa, K; Liu, J M

    2001-11-01

    Fanconi anemia (FA) is a genetic disorder that predisposes to hematopoietic failure, birth defects and cancer. We identified an interaction between the FA protein, FANCA and brm-related gene 1 (BRG1) product. BRG1 is a subunit of the SWI/SNF complex, which remodels chromatin structure through a DNA-dependent ATPase activity. FANCA was demonstrated to associate with the endogenous SWI/SNF complex. We also found a significant increase in the molecular chaperone, glucose-regulated protein 94 (GRP94) among BRG1-associated factors isolated from a FANCA-mutant cell line, which was not seen in either a normal control cell line or the mutant line complemented by wild-type FANCA. Despite this specific difference, FANCA did not appear to be absolutely required for in vitro chromatin remodeling. Finally, we demonstrated co-localization in the nucleus between transfected FANCA and BRG1. The physiological action of FANCA on the SWI/SNF complex remains to be clarified, but our work suggests that FANCA may recruit the SWI/SNF complex to target genes, thereby enabling coupled nuclear functions such as transcription and DNA repair.

  9. Measurements of Fundamental Fluid Physics of SNF Storage Canisters

    Energy Technology Data Exchange (ETDEWEB)

    Condie, Keith Glenn; Mc Creery, Glenn Ernest; McEligot, Donald Marinus

    2001-09-01

    With the University of Idaho, Ohio State University and Clarksean Associates, this research program has the long-term goal to develop reliable predictive techniques for the energy, mass and momentum transfer plus chemical reactions in drying / passivation (surface oxidation) operations in the transfer and storage of spent nuclear fuel (SNF) from wet to dry storage. Such techniques are needed to assist in design of future transfer and storage systems, prediction of the performance of existing and proposed systems and safety (re)evaluation of systems as necessary at later dates. Many fuel element geometries and configurations are accommodated in the storage of spent nuclear fuel. Consequently, there is no one generic fuel element / assembly, storage basket or canister and, therefore, no single generic fuel storage configuration. One can, however, identify generic flow phenomena or processes which may be present during drying or passivation in SNF canisters. The objective of the INEEL tasks was to obtain fundamental measurements of these flow processes in appropriate parameter ranges.

  10. Spent Nuclear Fuel (SNF) Project Cold Vacuum Drying (CVD) Facility Operations Manual

    International Nuclear Information System (INIS)

    IRWIN, J.J.

    2000-01-01

    The mission of the Spent Nuclear Fuel (SNF) Project Cold Vacuum Drying Facility (CVDF) is to achieve the earliest possible removal of free water from Multi-Canister Overpacks (MCOs). The MCOs contain metallic uranium SNF that have been removed from the 100K Area fuel storage water basins (i.e., the K East and K West Basins) at the US. Department of Energy Hanford Site in Southeastern Washington state. Removal of free water is necessary to halt water-induced corrosion of exposed uranium surfaces and to allow the MCOs and their SNF payloads to be safely transported to the Hanford Site 200 East Area and stored within the SNF Project Canister Storage Building (CSB). The CVDF is located within a few hundred yards of the basins, southwest of the 165KW Power Control Building and the 105KW Reactor Building. The site area required for the facility and vehicle circulation is approximately 2 acres. Access and egress is provided by the main entrance to the 100K inner area using existing roadways. The CVDF will remove free. water from the MCOs to reduce the potential for continued fuel-water corrosion reactions. The cold vacuum drying process involves the draining of bulk water from the MCO and subsequent vacuum drying. The MCO will be evacuated to a pressure of 8 torr or less and backfilled with an inert gas (helium). The MCO will be sealed, leak tested, and then transported to the CSB within a sealed shipping cask. (The MCO remains within the same shipping Cask from the time it enters the basin to receive its SNF payload until it is removed from the Cask by the CSB MCO handling machine.) The CVDF subproject acquired the required process systems, supporting equipment, and facilities. The cold vacuum drying operations result in an MCO containing dried fuel that is prepared for shipment to the CSB by the Cask transportation system. The CVDF subproject also provides equipment to dispose of solid wastes generated by the cold vacuum drying process and transfer process water removed

  11. A method for selection of spent nuclear fuel (SNF) transportation route considering socioeconomic cost based on contingent valuation method (CVM)

    International Nuclear Information System (INIS)

    Kim, Young Sik

    2008-02-01

    A transportation of SNF may cause an additional radiation exposure to human beings. It means that the radiological risk should be estimated and managed quantitatively for the public who live near the shipments route. Before the SNF transportation is performed, the route selection is concluded based on the radiological risk estimated with RADTRAN code in existing method generally. It means the existing method for route selection is based only on the radiological health risk but there are not only the impacts related to the radiological health risk but also the socioeconomic impacts related to the cost. In this study, a new method and its numerical formula for route selection on transporting SNF is proposed based on cost estimation because there are several costs in transporting SNF. The total cost consists of radiological health cost, transportation cost, and socioeconomic cost. Each cost is defined properly to the characteristics of SNF transportation and many coefficients and variables describing the meaning of each cost are obtained or estimated through many surveys. Especially to get the socioeconomic cost, contingent valuation method (CVM) is used with a questionnaire. The socioeconomic cost estimation is the most important part of the total cost originated from transporting SNF because it is a very dominant cost in the total cost. The route selection regarding SNF transportation can be supported with the proposed method reasonably and unnecessary or exhausting controversies about the shipments could be avoided

  12. Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator

    DEFF Research Database (Denmark)

    Usaite, Renata; Jewett, Michael Christopher; Soberano de Oliveira, Ana Paula

    2009-01-01

    Highly conserved among eukaryotic cells, the AMP-activated kinase (AMPK) is a central regulator of carbon metabolism. To map the complete network of interactions around AMPK in yeast (Snf1) and to evaluate the role of its regulatory subunit Snf4, we measured global mRNA, protein and metabolite...

  13. A review of human factors causations in commercial air transport accidents and incidents: From to 2000-2016

    Science.gov (United States)

    Kharoufah, Husam; Murray, John; Baxter, Glenn; Wild, Graham

    2018-05-01

    Human factors have been defined by the International Civil Aviation Organization (ICAO) as "about people in their living and working situations; about their relationship with machines, with procedures and with the environment about them; and about their relationships with other people (at work)". Human factors contribute to approximately 75% of aircraft accidents and incidents. As such, understanding their influence is essential to improve safety in the aviation industry. This study examined the different human factors causations in a random sample of over 200 commercial air transport accidents and incidents from 2000 to 2016. The main objective of this study was to identify the principal human factor contributions to aviation accidents and incidents. An exploratory research design was utilised. The qualitative data were recorded in a database, and were coded into categories about the flights (including date, manufacturer, carrier, state of occurrence, etc). These categories were then analysed using Chi-Squared tests to determine which were statistically significant in terms of having an influence on the accidents/incidents. The most significant human factor was found to be situational awareness followed by non-adherence to procedures. In addition, charter operations proved to have a significantly higher rate of human factor related occurrence as compared to other type of operations. A significant finding was that Africa has a high rate of accidents/incidents relative to the amount of traffic and aircraft movements. These findings reflect some of the more noteworthy incidents that have received significant media attention, including Air Asia 8501 on the 28th of December 2014, TransAsia Airways 235 on the 4th of February 2015, and Air France 447 on the 1st of June 2009; these accidents resulted in a significant loss of lives where situational awareness and non-adherence to procedures were significant contributing factors.

  14. Will the world SNF be reprocessed in Russia?

    International Nuclear Information System (INIS)

    Gagarinski, A.

    2000-01-01

    Russia's possibilities in nuclear fuel reprocessing are well known. RT-1 plant with 400 tons/year in the Chelyabinsk region can provide reprocessing of fuel from Russian and Central European WWER-440 reactors, as well as from transport and research reactors. Former military complex Krasnoyarsk-26 with unique underground installations situated in rock galleries, already has an aqueous facility for storage of 6000 tons of spent nuclear fuel (SNF), half-built plant RT-2 for nuclear fuel reprocessing with 1500 tons/year capacity, as well as the projects of dry storage facility for 30000 tons of SNF and of MOX fuel production plant. Russian nuclear specialists understand well, that the economic efficiency of nuclear fuel reprocessing industry is shown only in case of large-scale production, which would require consolidation of the countries, which develop nuclear energy. They also understand, that Russia has all the possibilities to become one of the centers of such a consolidation and to use these possibilities for the benefit of the country. The idea of foreign nuclear fuel reprocessing (for a long time realized for East and Central European countries, which operate Soviet-design reactors) has existed in the specialists' minds, and sometimes has appeared in the mass media. On the other hand, rehabilitation of territories of nuclear fuel cycle enterprises in Russia continues, including the Karachai lake, which contains 120 million Curie of radioactivity. Unfortunately, Russia simply has no money for complete solution of the problems of radiation military legacy. During discussion of the budget for 2000, the Russian Minatom has made a daring step. A real program, how to find money needed for solving the 'radiation legacy' problem, was proposed. With this purpose, it was proposed to permit storage and further reprocessing of other countries' SNF on Russian territory. It is well known, that another countries' SNF is accepted for reprocessing by UK and France, and Russia

  15. Conditions With High Intracellular Glucose Inhibit Sensing Through Glucose Sensor Snf3 in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Karhumaa, Kaisa; Wu, B.Q.; Kielland-Brandt, Morten

    2010-01-01

    as for amino acids. An alternating-access model of the function of transporter-like sensors has been previously suggested based on amino acid sensing, where intracellular ligand inhibits binding of extracellular ligand. Here we studied the effect of intracellular glucose on sensing of extracellular glucose...... through the transporter-like sensor Snf3 in yeast. Sensing through Snf3 was determined by measuring degradation of Mth1 protein. High intracellular glucose concentrations were achieved by using yeast strains lacking monohexose transporters which were grown on maltose. The apparent affinity...... of extracellular glucose to Snf3 was measured for cells grown in non-fermentative medium or on maltose. The apparent affinity for glucose was lowest when the intracellular glucose concentration was high. The results conform to an alternating-access model for transporter-like sensors. J. Cell. Biochem. 110: 920...

  16. SNF sludge treatment system preliminary project execution plan

    International Nuclear Information System (INIS)

    Flament, T.A.

    1998-01-01

    The Fluor Daniel Hanford, Inc. (FDH) Project Director for the Spent Nuclear Fuel (SNF) Project has requested Numatec Hanford Company (NHC) to define how Hanford would manage a new subproject to provide a process system to receive and chemically treat radioactive sludge currently stored in the 100 K Area fuel retention basins. The subproject, named the Sludge Treatment System (STS) Subproject, provides and operates facilities and equipment to chemically process K Basin sludge to meet Tank Waste Remediation System (TWRS) requirements. This document sets forth the NHC management approach for the STS Subproject and will comply with the requirements of the SNF Project Management Plan (HNF-SD-SNFPMP-011). This version of this document is intended to apply to the initial phase of the subproject and to evolve through subsequent revision to include all design, fabrication, and construction conducted on the project and the necessary management and engineering functions within the scope of the subproject. As Project Manager, NHC will perform those activities necessary to complete the STS Subproject within approved cost and schedule baselines and turn over to FDH facilities, systems, and documentation necessary for operation of the STS

  17. Regulatory Experiences from Effective Step-wise Implementation of the SNF Disposal in Finland

    International Nuclear Information System (INIS)

    Hämäläinen, K.

    2016-01-01

    Finland is one of the foremost countries in the world in developing a disposal solution for spent nuclear fuel (SNF). The Construction License Application (CLA) for the Olkiluoto SNF encapsulation and disposal facility was submitted by Posiva, the implementer, to the authorities at the end of 2012 and the Government is expected to decide about the license during autumn 2015. In 1983 the Government made a strategy decision on the objectives and target time schedule for the research, development and technical planning of nuclear waste management. Decision included the milestones for site selection, submittal of construction license and start of disposal operations.

  18. SOURCE OF BURNUP VALUES FOR COMMERCIAL SPENT NUCLEAR FUEL ASSEMBLIES

    International Nuclear Information System (INIS)

    BSC

    2004-01-01

    Waste packages are loaded with commercial spent nuclear fuel (SNF) that satisfies the minimum burnup requirements of a criticality loading curve. The burnup value assigned by the originating nuclear utility to each SNF assembly (assigned burnup) is used to load waste packages in compliance with a criticality loading curve. The burnup provided by a nuclear utility has uncertainties, so conservative calculation methods are used to characterize those uncertainties for incorporation into the criticality loading curves. Procedural safety controls ensure that the correct assembly is loaded into each waste package to prevent a misload that could create a condition affecting the safety margins. Probabilistic analyses show that procedural safety controls can minimize the chance of a misload but can not completely eliminate the possibility. Physical measurements of burnup with instrumentation in the surface facility are not necessary due to the conservative calculation methods used to produce the criticality loading curves. The reactor records assigned burnup of a commercial SNF assembly contains about two percent uncertainty, which is increased to five-percent to ensure conservatism. This five-percent uncertainty is accommodated by adjusting the criticality loading curve. Also, the record keeping methods of nuclear utilities are not uniform and the level of detail required by the NRC has varied over the last several decades. Thus, some SNF assemblies may have assigned burnups that are averages for a batch of assemblies with similar characteristics. Utilities typically have access to more detailed core-follow records that allow the batch average burnup to be changed to an assembly specific burnup. Alternatively, an additional safety margin is incorporated into the criticality loading curve to accommodate SNF assemblies with batch average burnups or greater uncertainties due to the methodology used by the nuclear utility. The utility records provide the assembly identifier

  19. A contingency safe, responsible, economic, increased capacity spent nuclear fuel (SNF) advance fuel cycle

    International Nuclear Information System (INIS)

    Levy, S.

    2008-01-01

    planned to be authorized by the U.S. Congress for commercial SNF and nuclear weapons would amount to only one quarter of the needs by 2100. The contingency strategy proposes to Recognize the presence of Transuranics (TRUs) at YM due to defense wastes being disposed there. Discourage the accumulation of separated Pu to satisfy the National Energy Policy Development Group of May 2001. Dispose the 'oldest' once-through fuel at YM due to its reduced burn up, decay heat, and Transuranics (TRUs) content and to use the NRC to be approved Total System Performance Analysis (TSPA) methodology to show that its impact on dose would be minimal compared to the dose 'performance floor' set by defense wastes (4). Avoid disposal of radioactive products at YM which do not need long isolation periods, i.e. Uranium (U), short term fission products, including Cesium and Strontium which can be allowed to decay separately in order to reduce the heat produced in SNF at YM(5). That element of the strategy will reduce significantly the material volume reaching YM. Stabilize the fission products capable of migrating, e.g. fixing the technetium in a matrix with cladding hulls (3) and capturing iodine in a stable solid waste form because its meteorological release as carried out in France will not be allowed in the U. S. Burn TRUs in LWRs in 10 to 20 percent fertile free fuel (FFF) or annular inert matrix fuel (IMF) rods using zirconia, ZrO 2 and its cubic phase stabilized with Ytria (Y 2 O 3 ) and including a burnable poison (erbia for pressurized water and gadolinia for boiling water reactors). References (6) and (7) show that after one fuel cycle, the Pu content of IMF is 'highly undesirable' or 'conceivably unusable '. Disposition the separable IMF fuel rods at YM after one cycle to avoid multiple costly recycles because, as noted in reference (8), 'cubic zirconia is attractive as both a nuclear fuel-form and a nuclear waste form because it is an actinide host phase'. The proposed SNF contingency

  20. 42 CFR 424.20 - Requirements for posthospital SNF care.

    Science.gov (United States)

    2010-10-01

    ... statements may be signed by— (1) The physician responsible for the case or, with his or her authorization, by a physician on the SNF staff or a physician who is available in case of an emergency and has knowledge of the case; or (2) A nurse practitioner or clinical nurse specialist, neither of whom has a...

  1. Radioecological consequences of a potential accident during transport of spent nuclear fuel along an Arctic coastline

    International Nuclear Information System (INIS)

    Iosjpe, M.; Reistad, O.; Amundsen, I.B.

    2009-01-01

    This article presents results pertaining to a risk assessment of the potential consequences of a hypothetical accident occurring during the transportation by ship of spent nuclear fuel (SNF) along an Arctic coastline. The findings are based on modelling of potential releases of radionuclides, radionuclide transport and uptake in the marine environment. Modelling work has been done using a revised box model developed at the Norwegian Radiation Protection Authority. Evaluation of the radioecological consequences of a potential accident in the southern part of the Norwegian Current has been made on the basis of calculated collective dose to man, individual doses for the critical group, concentrations of radionuclides in seafood and doses to marine organisms. The results of the calculations indicate a large variability in the investigated parameters above mentioned. On the basis of the calculated parameters the maximum total activity ('accepted accident activity') in the ship, when the parameters that describe the consequences after the examined potential accident are still in agreement with the recommendations and criterions for protection of the human population and the environment, has been evaluated

  2. Epidemiology o.f· Traffic Accidents

    African Journals Online (AJOL)

    Accidents. An analysis of some 2 100 fatal traffic accidents gave the following results: males-79%; females-21%; a ratio of 4: 1. The high proportion of males to females killed in traffic accidents may be due to the fact that (a) more males commute daily in private and commercial vehicles;. (b) more females commute daily in ...

  3. Spent Nuclear Fuel (SNF) Project Cold Vacuum Drying (CVD) Facility Operations Manual

    Energy Technology Data Exchange (ETDEWEB)

    IRWIN, J.J.

    2000-02-03

    This document provides the Operations Manual for the Cold Vacuum Drying Facility (CVDF). The Manual was developed in conjunction with HNF-SD-SNF-SAR-002, Safety Analysis Report for the Cold Vacuum Drying Facility, Phase 2, Supporting Installation of the Processing Systems (Garvin 1998) and, the HNF-SD-SNF-DRD-002, 1997, Cold Vacuum Drying Facility Design Requirements, Rev. 3a. The Operations Manual contains general descriptions of all the process, safety and facility systems in the CVDF, a general CVD operations sequence, and has been developed for the spent nuclear fuel project (SNFP) Operations Organization and shall be updated, expanded, and revised in accordance with future design, construction and startup phases of the CVDF until the CVDF final ORR is approved.

  4. Spent Nuclear Fuel (SNF) Project Cold Vacuum Drying (CVD) Facility Operations Manual

    International Nuclear Information System (INIS)

    IRWIN, J.J.

    2000-01-01

    This document provides the Operations Manual for the Cold Vacuum Drying Facility (CVDF). The Manual was developed in conjunction with HNF-SD-SNF-SAR-002, Safety Analysis Report for the Cold Vacuum Drying Facility, Phase 2, Supporting Installation of the Processing Systems (Garvin 1998) and, the HNF-SD-SNF-DRD-002, 1997, Cold Vacuum Drying Facility Design Requirements, Rev. 3a. The Operations Manual contains general descriptions of all the process, safety and facility systems in the CVDF, a general CVD operations sequence, and has been developed for the spent nuclear fuel project (SNFP) Operations Organization and shall be updated, expanded, and revised in accordance with future design, construction and startup phases of the CVDF until the CVDF final ORR is approved

  5. A SWI/SNF Chromatin Remodelling Protein Controls Cytokinin Production through the Regulation of Chromatin Architecture

    KAUST Repository

    Jégu, Teddy

    2015-10-12

    Chromatin architecture determines transcriptional accessibility to DNA and consequently gene expression levels in response to developmental and environmental stimuli. Recently, chromatin remodelers such as SWI/SNF complexes have been recognized as key regulators of chromatin architecture. To gain insight into the function of these complexes during root development, we have analyzed Arabidopsis knock-down lines for one sub-unit of SWI/SNF complexes: BAF60. Here, we show that BAF60 is a positive regulator of root development and cell cycle progression in the root meristem via its ability to down-regulate cytokinin production. By opposing both the deposition of active histone marks and the formation of a chromatin regulatory loop, BAF60 negatively regulates two crucial target genes for cytokinin biosynthesis (IPT3 and IPT7) and one cell cycle inhibitor (KRP7). Our results demonstrate that SWI/SNF complexes containing BAF60 are key factors governing the equilibrium between formation and dissociation of a chromatin loop controlling phytohormone production and cell cycle progression.

  6. A SWI/SNF Chromatin Remodelling Protein Controls Cytokinin Production through the Regulation of Chromatin Architecture

    KAUST Repository

    Jé gu, Teddy; Domenichini, Sé verine; Blein, Thomas; Ariel, Federico; Christ, Auré lie; Kim, SoonKap; Crespi, Martin; Boutet-Mercey, Sté phanie; Mouille, Gré gory; Bourge, Mickaë l; Hirt, Heribert; Bergounioux, Catherine; Raynaud, Cé cile; Benhamed, Moussa

    2015-01-01

    Chromatin architecture determines transcriptional accessibility to DNA and consequently gene expression levels in response to developmental and environmental stimuli. Recently, chromatin remodelers such as SWI/SNF complexes have been recognized as key regulators of chromatin architecture. To gain insight into the function of these complexes during root development, we have analyzed Arabidopsis knock-down lines for one sub-unit of SWI/SNF complexes: BAF60. Here, we show that BAF60 is a positive regulator of root development and cell cycle progression in the root meristem via its ability to down-regulate cytokinin production. By opposing both the deposition of active histone marks and the formation of a chromatin regulatory loop, BAF60 negatively regulates two crucial target genes for cytokinin biosynthesis (IPT3 and IPT7) and one cell cycle inhibitor (KRP7). Our results demonstrate that SWI/SNF complexes containing BAF60 are key factors governing the equilibrium between formation and dissociation of a chromatin loop controlling phytohormone production and cell cycle progression.

  7. Evaluation of Radionuclide Release from Aluminum-Based SNF in Basin Storage

    International Nuclear Information System (INIS)

    Sindelar, R.L.; Burke, S.D.; Howell, J.P.

    1998-09-01

    This report provides an evaluation of the release rates of radionuclides from breached A1-SNF assemblies and evaluates the effect of direct storage of breached fuel at a conservative upper bound reference condition on the SRS basin water activity levels

  8. Serbian SNF Repatriation Operation. Issues, Solving, Lesson

    Energy Technology Data Exchange (ETDEWEB)

    Smirnov, A. [Research and Development Company ' Sosny' , Moscow (Russian Federation)

    2011-07-01

    For now the removal of SNF from RA reactor site (PC NFS, Serbia) is the most time-consuming and technically complicated operation under RRRFR Program. The most efficient techniques and lessons learned from other projects of the RRRFR Program as well as new unique technical decisions were used. Two big challenges were resolved during implementation of Serbian Project: (1) preparation of damaged fuel located in the packages unsuitable for transport, taking into account insufficient infrastructure of RA reactor site and (2) removal of large amount of fuel in one multimodal shipment through several transit countries. The main attention was paid to safety justification of all activities. All approvals were obtained in Russia, Serbia and transit countries. Special canisters were designed for transportation of specific RA reactor fuel (of small dimensions, unidentifiable, damaged due to corrosion). The canister design was selected to be untight - it was the most expedient decision for that case from safety perspective. The technology and a set of equipment were designed for remote removal of the fuel from the existing package (aluminum barrels and reactor channels) and placing of the fuel into the new canisters. After fabrication and assembling of the equipment theoretical and practical training of the personnel was performed. Fuel repackaging took about 5 months. SNF was transported in TUK-19 and SKODA VPVR/M casks. The baskets of large capacity were designed and fabricated for SKODA VPVR/M casks. Special requirements to drying the packages and composition of gaseous medium inside were justified to ensure fire and explosion safety. Specialized ISO-containers and transfer equipment designed under Romanian Project were used together with TUK-19 casks. A forklift and mobile rail system were used to handle SKODA VPVR/M casks under conditions of low capacity of the cranes at the facility. Due to the tight schedule of RRRFR Program as well as geographical peculiarities of RA

  9. Safety aspects of spent nuclear fuel interim storage installations

    Energy Technology Data Exchange (ETDEWEB)

    Romanato, Luiz Sergio [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), Sao Paulo, SP (Brazil). Dept. da Qualidade. Div. de Sistemas da Qualidade]. E-mail: romanato@ctmsp.mar.mil.br; Rzyski, Barbara Maria [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Div. de Ensino]. E-mail: bmrzyski@ipen.br

    2007-07-01

    Nowadays safety and security of spent nuclear fuel (SNF) interim storage installations are very important, due to a great concentration of fission products, actinides and activation products. In this kind of storage it is necessary to consider the physical security. Nuclear installations have become more vulnerable. New types of accidents must be considered in the design of these installations, which in the early days were not considered like: fissile material stolen, terrorists' acts and war conflicts, and traditional accidents concerning the transport of the spent fuel from the reactor to the storage location, earthquakes occurrence, airplanes crash, etc. Studies related to airplane falling had showed that a collision of big commercials airplanes at velocity of 800 km/h against SNF storage and specially designed concrete casks, do not result in serious structural injury to the casks, and not even radionuclides liberation to the environment. However, it was demonstrated that attacks with modern military ammunitions, against metallic casks, are calamitous. The casks could not support a direct impact of this ammo and the released radioactive materials can expose the workers and public as well the local environment to harmful radiation. This paper deals about the main basic aspects of a dry SNF storage installation, that must be physically well protected, getting barriers that difficult the access of unauthorized persons or vehicles, as well as, must structurally resist to incidents or accidents caused by unauthorized intrusion. (author)

  10. Safety aspects of spent nuclear fuel interim storage installations

    International Nuclear Information System (INIS)

    Romanato, Luiz Sergio

    2007-01-01

    Nowadays safety and security of spent nuclear fuel (SNF) interim storage installations are very important, due to a great concentration of fission products, actinides and activation products. In this kind of storage it is necessary to consider the physical security. Nuclear installations have become more vulnerable. New types of accidents must be considered in the design of these installations, which in the early days were not considered like: fissile material stolen, terrorists' acts and war conflicts, and traditional accidents concerning the transport of the spent fuel from the reactor to the storage location, earthquakes occurrence, airplanes crash, etc. Studies related to airplane falling had showed that a collision of big commercials airplanes at velocity of 800 km/h against SNF storage and specially designed concrete casks, do not result in serious structural injury to the casks, and not even radionuclides liberation to the environment. However, it was demonstrated that attacks with modern military ammunitions, against metallic casks, are calamitous. The casks could not support a direct impact of this ammo and the released radioactive materials can expose the workers and public as well the local environment to harmful radiation. This paper deals about the main basic aspects of a dry SNF storage installation, that must be physically well protected, getting barriers that difficult the access of unauthorized persons or vehicles, as well as, must structurally resist to incidents or accidents caused by unauthorized intrusion. (author)

  11. Legal precedents regarding use and defensibility of risk assessment in Federal transportation of SNF and HLW

    International Nuclear Information System (INIS)

    Bentz, E.J. Jr.; Bentz, C.B.; O'Hora, T.D.; Chen, S.Y.

    1997-01-01

    Risk assessment has become an increasingly important and essential tool in support of Federal decision-making regarding the handling, storage, disposal, and transportation of spent nuclear fuel (SNF) and high-level radioactive waste (HLW). This paper analyzes the current statutory and regulatory framework and related legal precedents with regard to SNF and HLW transportation. The authors identify key scientific and technical issues regarding the use and defensibility of risk assessment in Federal decision-making regarding anticipated shipments

  12. Coffin-Siris syndrome is a SWI/SNF complex disorder.

    Science.gov (United States)

    Tsurusaki, Y; Okamoto, N; Ohashi, H; Mizuno, S; Matsumoto, N; Makita, Y; Fukuda, M; Isidor, B; Perrier, J; Aggarwal, S; Dalal, A B; Al-Kindy, A; Liebelt, J; Mowat, D; Nakashima, M; Saitsu, H; Miyake, N; Matsumoto, N

    2014-06-01

    Coffin-Siris syndrome (CSS) is a congenital disorder characterized by intellectual disability, growth deficiency, microcephaly, coarse facial features, and hypoplastic or absent fifth fingernails and/or toenails. We previously reported that five genes are mutated in CSS, all of which encode subunits of the switch/sucrose non-fermenting (SWI/SNF) ATP-dependent chromatin-remodeling complex: SMARCB1, SMARCA4, SMARCE1, ARID1A, and ARID1B. In this study, we examined 49 newly recruited CSS-suspected patients, and re-examined three patients who did not show any mutations (using high-resolution melting analysis) in the previous study, by whole-exome sequencing or targeted resequencing. We found that SMARCB1, SMARCA4, or ARID1B were mutated in 20 patients. By examining available parental samples, we ascertained that 17 occurred de novo. All mutations in SMARCB1 and SMARCA4 were non-truncating (missense or in-frame deletion) whereas those in ARID1B were all truncating (nonsense or frameshift deletion/insertion) in this study as in our previous study. Our data further support that CSS is a SWI/SNF complex disorder. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity

    International Nuclear Information System (INIS)

    Kothandapani, Anbarasi; Gopalakrishnan, Kathirvel; Kahali, Bhaskar; Reisman, David; Patrick, Steve M.

    2012-01-01

    Chromatin remodeling complex SWI/SNF plays important roles in many cellular processes including transcription, proliferation, differentiation and DNA repair. In this report, we investigated the role of SWI/SNF catalytic subunits Brg1 and Brm in the cellular response to cisplatin in lung cancer and head/neck cancer cells. Stable knockdown of Brg1 and Brm enhanced cellular sensitivity to cisplatin. Repair kinetics of cisplatin DNA adducts revealed that downregulation of Brg1 and Brm impeded the repair of both intrastrand adducts and interstrand crosslinks (ICLs). Cisplatin ICL-induced DNA double strand break repair was also decreased in Brg1 and Brm depleted cells. Altered checkpoint activation with enhanced apoptosis as well as impaired chromatin relaxation was observed in Brg1 and Brm deficient cells. Downregulation of Brg1 and Brm did not affect the recruitment of DNA damage recognition factor XPC to cisplatin DNA lesions, but affected ERCC1 recruitment, which is involved in the later stages of DNA repair. Based on these results, we propose that SWI/SNF chromatin remodeling complex modulates cisplatin cytotoxicity by facilitating efficient repair of the cisplatin DNA lesions. -- Highlights: ► Stable knockdown of Brg1 and Brm enhances cellular sensitivity to cisplatin. ► Downregulation of Brg1 and Brm impedes the repair of cisplatin intrastrand adducts and interstrand crosslinks. ► Brg1 and Brm deficiency results in impaired chromatin relaxation, altered checkpoint activation as well as enhanced apoptosis. ► Downregulation of Brg1 and Brm affects recruitment of ERCC1, but not XPC to cisplatin DNA lesions.

  14. Implications of the accident at Chernobyl for safety regulation of commercial nuclear power plants in the United States: Volume 1, Main report: Final report

    International Nuclear Information System (INIS)

    1989-04-01

    This report was prepared by the Nuclear Regulatory Commission (NRC) staff to assess the implications of the accident at the Chernobyl nuclear power plant as they relate to reactor safety regulation for commercial nuclear power plants in the United States. The facts used in this assessment have been drawn from the US fact-finding report (NUREG-1250) and its sources. The general conclusions of the document are that there are generic lessons to be learned but that no changes in regulations are needed due to the substantial differences in the design, safety features and operation of US plants as compared to those in the USSR. Given these general conclusions, further consideration of certain specific areas is recommended by the report. These include: administrative controls over reactor regulation, reactivity accidents, accidents at low or zero power, multi-unit protection, fires, containment, emergency planning, severe accident phenomena, and graphite-moderated reactors

  15. National spent fuel program preliminary report RCRA characteristics of DOE-owned spent nuclear fuel DOE-SNF-REP-002. Revision 3

    International Nuclear Information System (INIS)

    1995-07-01

    This report presents information on the preliminary process knowledge to be used in characterizing all Department of Energy (DOE)-owned Spent Nuclear Fuel (SNF) types that potentially exhibit a Resource Conservation and Recovery Act (RCRA) characteristic. This report also includes the process knowledge, analyses, and rationale used to preliminarily exclude certain SNF types from RCRA regulation under 40 CFR section 261.4(a)(4), ''Identification and Listing of Hazardous Waste,'' as special nuclear and byproduct material. The evaluations and analyses detailed herein have been undertaken as a proactive approach. In the event that DOE-owned SNF is determined to be a RCRA solid waste, this report provides general direction for each site regarding further characterization efforts. The intent of this report is also to define the path forward to be taken for further evaluation of specific SNF types and a recommended position to be negotiated and established with regional and state regulators throughout the DOE Complex regarding the RCRA-related policy issues

  16. National spent fuel program preliminary report RCRA characteristics of DOE-owned spent nuclear fuel DOE-SNF-REP-002. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This report presents information on the preliminary process knowledge to be used in characterizing all Department of Energy (DOE)-owned Spent Nuclear Fuel (SNF) types that potentially exhibit a Resource Conservation and Recovery Act (RCRA) characteristic. This report also includes the process knowledge, analyses, and rationale used to preliminarily exclude certain SNF types from RCRA regulation under 40 CFR {section}261.4(a)(4), ``Identification and Listing of Hazardous Waste,`` as special nuclear and byproduct material. The evaluations and analyses detailed herein have been undertaken as a proactive approach. In the event that DOE-owned SNF is determined to be a RCRA solid waste, this report provides general direction for each site regarding further characterization efforts. The intent of this report is also to define the path forward to be taken for further evaluation of specific SNF types and a recommended position to be negotiated and established with regional and state regulators throughout the DOE Complex regarding the RCRA-related policy issues.

  17. Characterization of FRR SNF in Basin and Dry Storage Systems

    International Nuclear Information System (INIS)

    Brooks, H.M.; Sindelar, R.L.

    1998-09-01

    Since May 1996, over 1700 aluminum-based spent nuclear fuel (A1-SNF) assemblies have been inspected for corrosion and mechanical damage to determine if the cladding had been penetrated as part of the process for acceptance of the fuel at the Savannah River Site (SRS). The results of the release measurements are summarized in this paper

  18. SNF project engineering process improvement plan

    International Nuclear Information System (INIS)

    KELMENSON, R.L.

    1999-01-01

    This Engineering Process Improvement Plan documents the activities and plans to be taken by the SNF Project (the Project) to support its engineering process and to produce a consolidated set of engineering procedures that are fully compliant with the requirements of HNF-PRO-1819 (1819). These requirements are imposed on all engineering activities performed for the Project and apply to all life-cycle stages of the Project's systems, structures and components (SSCs). This Plan describes the steps that will be taken by the Project during the transition period to ensure that new procedures are effectively integrated into the Project's work process as these procedures are issued. The consolidated procedures will be issued and implemented by September 30, 1999

  19. Receipt capability for foreign research reactor (FRR) spent nuclear fuel (SNF) at the Savannah River Site (SRS)

    International Nuclear Information System (INIS)

    Clark, William D. Jr.

    1997-01-01

    The United Stated Department of Energy began implementation of the ten year FRR SNF return policy in May, 1996. Seventeen months into the thirteen year return program, four shipments have been made, returning 863 assemblies of aluminum clad SNF to SRS. Five additional shipments containing over 1,200 assemblies are scheduled in fiscal year 1998. During negotiation of contracts with various reactor operators, it has become apparent that many facilities wish to delay the return of their SNF until the latter part of the program. This has raised concern on the part of the DOE that insufficient receipt capability will exist during the last three to five years of the program to ensure the return of all of the SNF. To help quantify this issue and ensure that it is addressed early in the program, a computer simulation model has been developed at SRS to facilitate the planning, scheduling, and analysis of SNF shipments to be received from offsite facilities. The simulation model, called OFFSHIP, greatly reduces the time and effort required to analyze the complex global transportation system that involves dozens of reactor facilities, multiple casks and fuel types, and time-dependent SNF inventories. OFFSHIP allows the user to input many variables including priorities, cask preferences, shipping date preferences, turnaround times, and regional groupings. User input is easily managed using a spreadsheet format and the output data is generated in a spreadsheet format to facilitate detailed analysis and prepare graphical results. The model was developed in Microsoft Visual Basic for Applications and runs native in Microsoft Excel. The receipt schedules produced by the model have been compared to schedules generated manually with consistent results. For the purposes of this presentation, four scenarios have been developed. The 'Base Case' accounts for those countries/facilities that DOE believes may not participate in the return program. The three additional scenarios look at the

  20. Dentofacial injuries in commercial motorcycle accidents in Cameroon

    African Journals Online (AJOL)

    Methods: This was a hospital based study conducted in 6 out of 10 regional ... large portion of road traffic accidents in developing ... networks, unplanned urban transportation with the ... This study was of 387 cases of dentofacial injuries at-.

  1. 327 SNF fuel return to K-Basin quality process plan

    International Nuclear Information System (INIS)

    Ham, J.E.

    1998-01-01

    The B and W Hanford Company's (BWHC) 327 Facility, in the 300 Area of the Hanford Site, contains Spent Nuclear Fuel (SNF) single fuel element canisters (SFEC) and fuel remnant canisters (FRC) which are to be returned to K-Basin. Seven shipments of up to six fuel canisters will be loaded into the CNS 1-13G Cask and transported to 105-KE

  2. Chromatin-remodeling SWI/SNF complex regulates coenzyme Q6 synthesis and a metabolic shift to respiration in yeast.

    Science.gov (United States)

    Awad, Agape M; Venkataramanan, Srivats; Nag, Anish; Galivanche, Anoop Raj; Bradley, Michelle C; Neves, Lauren T; Douglass, Stephen; Clarke, Catherine F; Johnson, Tracy L

    2017-09-08

    Despite its relatively streamlined genome, there are many important examples of regulated RNA splicing in Saccharomyces cerevisiae Here, we report a role for the chromatin remodeler SWI/SNF in respiration, partially via the regulation of splicing. We find that a nutrient-dependent decrease in Snf2 leads to an increase in splicing of the PTC7 transcript. The spliced PTC7 transcript encodes a mitochondrial phosphatase regulator of biosynthesis of coenzyme Q 6 (ubiquinone or CoQ 6 ) and a mitochondrial redox-active lipid essential for electron and proton transport in respiration. Increased splicing of PTC7 increases CoQ 6 levels. The increase in PTC7 splicing occurs at least in part due to down-regulation of ribosomal protein gene expression, leading to the redistribution of spliceosomes from this abundant class of intron-containing RNAs to otherwise poorly spliced transcripts. In contrast, a protein encoded by the nonspliced isoform of PTC7 represses CoQ 6 biosynthesis. Taken together, these findings uncover a link between Snf2 expression and the splicing of PTC7 and establish a previously unknown role for the SWI/SNF complex in the transition of yeast cells from fermentative to respiratory modes of metabolism. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. The remote methods for radwaste and SNF control

    International Nuclear Information System (INIS)

    Ivanov, O; Stepanov, V; Danilovich, A; Potapov, V

    2017-01-01

    With the examples of developments carried out in the Kurchatov Institute and by the world leaders in the field the presentation considers the devices and methods to obtain remotely information on the distribution of radioactivity in radwaste and SNF. It describes the different types of light portable gamma cameras. The application of scanning spectrometric systems is considers also. The methods of recording UV radiation for detection of alpha contamination with the luminescence of air are presented. We discuss the scope and tasks that can be solved using remote and non-destructive methods. (paper)

  4. Candida albicans Swi/Snf and Mediator Complexes Differentially Regulate Mrr1-Induced MDR1 Expression and Fluconazole Resistance.

    Science.gov (United States)

    Liu, Zhongle; Myers, Lawrence C

    2017-11-01

    Long-term azole treatment of patients with chronic Candida albicans infections can lead to drug resistance. Gain-of-function (GOF) mutations in the transcription factor Mrr1 and the consequent transcriptional activation of MDR1 , a drug efflux coding gene, is a common pathway by which this human fungal pathogen acquires fluconazole resistance. This work elucidates the previously unknown downstream transcription mechanisms utilized by hyperactive Mrr1. We identified the Swi/Snf chromatin remodeling complex as a key coactivator for Mrr1, which is required to maintain basal and induced open chromatin, and Mrr1 occupancy, at the MDR1 promoter. Deletion of snf2 , the catalytic subunit of Swi/Snf, largely abrogates the increases in MDR1 expression and fluconazole MIC observed in MRR1 GOF mutant strains. Mediator positively and negatively regulates key Mrr1 target promoters. Deletion of the Mediator tail module med3 subunit reduces, but does not eliminate, the increased MDR1 expression and fluconazole MIC conferred by MRR1 GOF mutations. Eliminating the kinase activity of the Mediator Ssn3 subunit suppresses the decreased MDR1 expression and fluconazole MIC of the snf2 null mutation in MRR1 GOF strains. Ssn3 deletion also suppresses MDR1 promoter histone displacement defects in snf2 null mutants. The combination of this work with studies on other hyperactive zinc cluster transcription factors that confer azole resistance in fungal pathogens reveals a complex picture where the induction of drug efflux pump expression requires the coordination of multiple coactivators. The observed variations in transcription factor and target promoter dependence of this process may make the search for azole sensitivity-restoring small molecules more complicated. Copyright © 2017 American Society for Microbiology.

  5. Canisters and nonfuel components at commercial nuclear reactors

    International Nuclear Information System (INIS)

    Gibbard, K.; Disbrow, J.

    1994-01-01

    This paper discusses detailed data on canisters and nonfuel components (NFC) at US commercial nuclear power reactors. A wide variety of NFC have been reported on the Form RW-859, open-quotes Nuclear Fuel Dataclose quotes survey. They may have been integral with an assembly, noncanistered in baskets, destined for disposal as low-level radioactive waste, or stored in canisters. Similarly, data on the family of canistered spent nuclear fuel (SNF) in storage pools was compiled. Approximately 85 percent of the 40,194 pieces of nonfuel assembly (NFA) hardware reported were integral with an assembly. This represents data submitted by 95 of the 107 reactors in 10 generic assembly classes. In addition, a total of 286 canisters have been reported as being in storage pools as of December 31, 1992. However, an additional 264 open baskets were also reported to contain miscellaneous SNF and nonfuel materials, garbage and debris. All of these 286 canisters meet the dimensional envelope requirements specified for disposal for open-quotes standard fuelclose quotes under the Standard Contract for Disposal of Spent Nuclear Fuel and/or High-Level Radioactive Waste (10 CFR 961); most of the baskets do not

  6. Modification of MELCOR for severe accident analysis of candidate accident tolerant cladding materials

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, Brad J., E-mail: brad.merrill@inl.gov; Bragg-Sitton, Shannon M., E-mail: shannon.bragg-sitton@inl.gov; Humrickhouse, Paul W., E-mail: paul.humrickhouse@inl.gov

    2017-04-15

    Highlights: • Accident tolerant fuels (ATF) systems are currently under development for LWRs. • Many performance analysis tools are specifically developed for UO{sub 2}–Zr alloy fuel. • Modifications were made to the MELCOR code for candidate ATF cladding. • Preliminary analysis results for SiC and FeCrAl cladding concepts are presented. - Abstract: A number of materials are currently under development as candidate accident tolerant fuel and cladding for application in the current fleet of commercial light water reactors (LWRs). The safe, reliable and economic operation of the nation’s nuclear power reactor fleet has always been a top priority for the nuclear industry. Continual improvement of technology, including advanced materials and nuclear fuels, remains central to the industry’s success. Enhancing the accident tolerance of light water reactors became a topic of serious discussion following the 2011 Great East Japan Earthquake, resulting tsunami, and subsequent damage to the Fukushima Daiichi nuclear power plant complex. The overall goal for the development of accident tolerant fuel (ATF) systems for LWRs is to identify alternative fuel system technologies to further enhance the safety, competitiveness, and economics of commercial nuclear power. Designed for use in the current fleet of commercial LWRs, or in reactor concepts with design certifications (GEN-III+), to achieve their goal enhanced ATF must endure loss of active cooling in the reactor core for a considerably longer period of time than the current fuel system, while maintaining or improving performance during normal operation. Many available nuclear fuel performance analysis tools are specifically developed for the current UO{sub 2}–Zirconium alloy fuel system. The MELCOR severe-accident analysis code, under development at the Sandia National Laboratory in New Mexico (SNL-NM) for the US Nuclear Regulatory Commission (NRC), is one of these tools. This paper describes modifications

  7. Management of severe accidents

    International Nuclear Information System (INIS)

    Jankowski, M.W.

    1987-01-01

    The definition and the multidimensionality aspects of accident management have been reviewed. The suggested elements in the development of a programme for severe accident management have been identified and discussed. The strategies concentrate on the two tiered approaches. Operative management utilizes the plant's equipment and operators capabilities. The recovery managment concevtrates on preserving the containment, or delaying its failure, inhibiting the release, and on strategies once there has been a release. The inspiration for this paper was an excellent overview report on perspectives on managing severe accidents in commercial nuclear power plants and extending plant operating procedures into the severe accident regime; and by the most recent publication of the International Nuclear Safety Advisory Group (INSAG) considering the question of risk reduction and source term reduction through accident prevention, management and mitigation. The latter document concludes that 'active development of accident management measures by plant personnel can lead to very large reductions in source terms and risk', and goes further in considering and formulating the key issue: 'The most fruitful path to follow in reducing risk even further is through the planning of accident management.' (author)

  8. Management of severe accidents

    International Nuclear Information System (INIS)

    Jankowski, M.W.

    1988-01-01

    The definition and the multidimensionality aspects of accident management have been reviewed. The suggested elements in the development of a programme for severe accident management have been identified and discussed. The strategies concentrate on the two tiered approaches. Operative management utilizes the plant's equipment and operators capabilities. The recovery management concentrates on preserving the containment, or delaying its failure, inhibiting the release, and on strategies once there has been a release. The inspiration for this paper was an excellent overview report on perspectives on managing severe accidents in commercial nuclear power plants and extending plant operating procedures into the severe accident regime; and by the most recent publication of the International Nuclear Safety Advisory Group (INSAG) considering the question of risk reduction and source term reduction through accident prevention, management and mitigation. The latter document concludes that active development of accident management measures by plant personnel can lead to very large reductions in source terms and risk, and goes further in considering and formulating the key issue: The most fruitful path to follow in reducing risk even further is through the planning of accident management

  9. SNF3 as high affinity glucose sensor and its function in supporting the viability of Candida glabrata under glucose-limited environment

    Directory of Open Access Journals (Sweden)

    Tzu Shan eNg

    2015-12-01

    Full Text Available Candida glabrata is an emerging human fungal pathogen that has efficacious nutrient sensing and responsiveness ability. It can be seen through its ability to thrive in diverse range of nutrient limited-human anatomical sites. Therefore, nutrient sensing particularly glucose sensing is thought to be crucial in contributing to the development and fitness of the pathogen. This study aimed to elucidate the role of SNF3 (Sucrose Non Fermenting 3 as a glucose sensor and its possible role in contributing to the fitness and survivability of C. glabrata in glucose-limited environment. The SNF3 knockout strain was constructed and subjected to different glucose concentrations to evaluate its growth, biofilm formation, amphotericin B susceptibility, ex vivo survivability and effects on the transcriptional profiling of the sugar receptor repressor (SRR pathway-related genes. The SNF3Δ strain showed a retarded growth in low glucose environments (0.01% and 0.1% in both fermentation and respiration-preferred conditions but grew well in high glucose concentration environments (1% and 2%. It was also found to be more susceptible to amphotericin B in low glucose environment (0.1% and macrophage engulfment but showed no difference in the biofilm formation capability. The deletion of SNF3 also resulted in the down-regulation of about half of hexose transporters genes (4 out of 9. Overall, the deletion of SNF3 causes significant reduction in the ability of C. glabrata to sense limited surrounding glucose and consequently disrupts its competency to transport and perform the uptake of this critical nutrient. This study highlighted the role of SNF3 as a high affinity glucose sensor and its role in aiding the survivability of C. glabrata particularly in glucose limited environment.

  10. DOCUMENTATION OF NATIONAL WEATHER CONDITIONS AFFECTING LONG-TERM DEGRADATION OF COMMERCIAL SPENT NUCLEAR FUEL AND DOE SPENT NUCLEAR FUEL AND HIGH-LEVEL WASTE

    International Nuclear Information System (INIS)

    W. L. Poe, Jr.; P.F. Wise

    1998-01-01

    The U.S. Department of Energy (DOE) is preparing a proposal to construct, operate 2nd monitor, and eventually close a repository at Yucca Mountain in Nye County, Nevada, for the geologic disposal of spent nuclear fuel (SNF) and high-level radioactive waste (HLW). As part of this effort, DOE has prepared a viability assessment and an assessment of potential consequences that may exist if the repository is not constructed. The assessment of potential consequences if the repository is not constructed assumes that all SNF and HLW would be left at the generator sites. These include 72 commercial generator sites (three commercial facility pairs--Salem and Hope Creek, Fitzpatrick and Nine Mile Point, and Dresden and Morris--would share common storage due to their close proximity to each other) and five DOE sites across the country. DOE analyzed the environmental consequences of the effects of the continued storage of these materials at these sites in a report titled Continued Storage Analysis Report (CSAR; Reference 1 ) . The CSAR analysis includes a discussion of the degradation of these materials when exposed to the environment. This document describes the environmental parameters that influence the degradation analyzed in the CSAR. These include temperature, relative humidity, precipitation chemistry (pH and chemical composition), annual precipitation rates, annual number of rain-days, and annual freeze/thaw cycles. The document also tabulates weather conditions for each storage site, evaluates the degradation of concrete storage modules and vaults in different regions of the country, and provides a thermal analysis of commercial SNF in storage

  11. Plan for Characterization of K Basin Spent Nuclear Fuel (SNF) and Sludge (OCRWM)

    International Nuclear Information System (INIS)

    TRIMBLE, D.J.

    2000-01-01

    This is an update of the plan for the characterization of spent nuclear fuel (SNF) and sludge stored in the Hanford K West and K East Basins. The purpose of the characterization program is to provide fuel and sludge data in support of the SNF Project in the effort to remove the fuel from the K Basins and place it into dry storage. Characterization of the K Basin fuel and sludge was initiated in 1994 and has been guided by the characterization plans (Abrefah 1994, Lawrence 1995a, Lawrence 1995b) and the characterization program management plan (PMP) (Lawrence 1995c, Lawrence 1998, Trimble 1999). The fuel characterization was completed in 1999. Summaries of these activities were documented by Lawrence (1999) and Suyama (1999). Lawrence (1999) is a summary report providing a road map to the detailed documentation of the fuel characterization. Suyama (1999) provides a basis for the limited characterization sample size as it relates to supporting design limits and the operational safety envelope for the SNF Project. The continuing sludge characterization is guided by a data quality objective (DQO) (Makenas 2000) and a sampling and analysis plan (SAP) (Baker, Welsh and Makenas 2000) The original intent of the characterization program was ''to provide bounding behavior for the fuel'' (Lawrence 1995a). To accomplish this objective, a fuel characterization program was planned that would provide data to augment data from the literature. The program included in-situ examinations of the stored fuel and laboratory testing of individual elements and small samples of fuel (Lawrence 1995a). Some of the planned tests were scaled down or canceled due to the changing needs of the SNF Project. The fundamental technical basis for the process that will be used to place the K Basin fuel into dry storage was established by several key calculations. These calculations characterized nominal and bounding behavior of fuel in Multi-Canister Overpacks (MCOs) during processing and storage

  12. Development Status of Accident Tolerant Fuels for Light Water Reactors in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Jae Ho; Kim, Hyun Gil; In, Wang Kee; Kim, Weon Ju; Koo, Yang Hyum [KAERI, Daejeon (Korea, Republic of); Lee, Seung Jae [KEPCONF, Daejeon (Korea, Republic of)

    2016-05-15

    Research on accident tolerant fuels (ATFs) is aimed at developing innovative fuels, which can mitigate or prevent the consequences of accidents. In Korea, innovative concepts are being developed to improve fuel safety and reliability of LWRs during accident events and normal operations. ATF technologies will be developed and commercialized through a sequence of long-lead and extensive activities. The interim milestone for new fuel program is that we would be ready for an irradiation test in commercial reactor by 2021. This presentation deals with the status of ATF development in KOREA and plan to implement new fuel technology successfully in commercial nuclear power plants.

  13. Interrelation of technologies for RW preparation and sites for final isolation of the wastes from pyrochemical processing of SNF

    Energy Technology Data Exchange (ETDEWEB)

    Gupalo, V.S.; Chistyakov, V.N. [JSC - Design-Prospecting and Scientific-Research Institute of Industrial Technology -, Kashirskoye Highway, 33, Moscow 115409 (Russian Federation); Kormilitsyn, M.V.; Kormilitsyna, L.A. [JSC - State Scientific Center - Research Institute of Atomic Reactors -, Ulyanovsk region, Dimitrovgrad - 10, 433510 (Russian Federation)

    2013-07-01

    For the justification of engineering solutions and practical testing of the radiochemical component of the perspective nuclear power complex with on-site variant of nuclear fuel cycle (NFC), it is planned to establish a multi-functional research-development complex (MFCRC) for radiochemical processing of spent nuclear fuels (SNF) from fast reactors. MFCRC is being established at the NIIAR site, it comprises technological process lines, where innovation pyro-electrochemical and hydrometallurgical technologies are realized, with an option for closing the inter-chain material flows for testing the combined radiochemically converted materials. The technological flowchart for processing at the MFCRC is subdivided into 3 segments: -) complex of the lead operations for dismantling the fuel elements (FE) and fuel assemblies (FA), -) pyrochemical extraction flowchart for processing SNF, and -) hydrometallurgical flowchart for processing SNF. The engineered solutions for the management and disposition of the radioactive wastes from MFCRC are reviewed.

  14. Standardization of Fat:SNF ratio of milk and addition of sprouted wheat fada (semolina) for the manufacture of halvasan.

    Science.gov (United States)

    Chaudhary, Apurva H; Patel, H G; Prajapati, P S; Prajapati, J P

    2015-04-01

    Traditional Indian Dairy Products such as Halvasan are manufactured in India using an age old practice. For manufacture of such products industrially, a standard formulation is required. Halvasan is a region specific, very popular heat desiccated milk product but has not been studied scientifically. Fat and Solids-not-fat (SNF) plays an important role in physico-chemical, sensory, textural characteristics and also the shelf life of any milk sweet. Hence for process standardization of Halvasan manufacture, different levels of Fat:SNF ratios i.e. 0.44, 0.55, 0.66 and 0.77 of milk were studied so that an optimum level yielding best organoleptic characteristics in final product can be selected. The product was made from milk standardized to these ratios of Fat:SNF and the product was manufactured as per the method tentatively employed on the basis of characterization of market samples of the product in laboratory. Based on the sensory results obtained, a Fat:SNF ratio of 0.66 for the milk has been selected. In the similar way, for standardizing the rate of addition of fada (semolina); 30, 40, 50 and 60 g fada (semolina) per kg of milk were added and based on the sensory observations, the level of fada (semolina) addition @50 gm/kg of milk was adjudged the best for Halvasan manufacture and hence selected.

  15. HANARO thermal hydraulic accident analysis

    Energy Technology Data Exchange (ETDEWEB)

    Park, Chul; Kim, Heon Il; Lee, Bo Yook; Lee, Sang Yong [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-06-01

    For the safety assessment of HANARO, accident analyses for the anticipated operational transients, accident scenarios and limiting accident scenarios were conducted. To do this, the commercial nuclear reactor system code. RELAP5/MOD2 was modified to RELAP5/KMRR; the thermal hydraulic correlations and the heat exchanger model was changed to incorporate HANARO characteristics. This report summarizes the RELAP/KMRR calculation results and the subchannel analyses results based on the RELAP/KMRR results. During the calculation, major concern was placed on the integrity of the fuel. For all the scenarios, the important accident analysis parameters, i.e., fuel centerline temperatures and the minimum critical heat flux ratio(MCHFR), satisfied safe design limits. It was verified, therefore, that the HANARO was safely designed. 21 tabs., 89 figs., 39 refs. (Author) .new.

  16. The TMI-2 accident

    International Nuclear Information System (INIS)

    Loureiro, L.A.

    1986-01-01

    A critical study about the technical and man-related facts in order to establish what is considered the worst commercial nuclear power accident until 1986. Radiological consequences and stress to the public are considered in contrast to antinuclear groups. This descriptive and technical study has the purpose to document written and oral opinions obtained abroad and then explain to the public in an easy language terminology. Preliminary study describing safety related systems fails and the accident itself with minute to minute description, conduct to the consequences and then, to learned lessons

  17. Spent Nuclear Fuel (SNF) Project Safety Basis Implementation Strategy

    International Nuclear Information System (INIS)

    TRAWINSKI, B.J.

    2000-01-01

    The objective of the Safety Basis Implementation is to ensure that implementation of activities is accomplished in order to support readiness to move spent fuel from K West Basin. Activities may be performed directly by the Safety Basis Implementation Team or they may be performed by other organizations and tracked by the Team. This strategy will focus on five key elements, (1) Administration of Safety Basis Implementation (general items), (2) Implementing documents, (3) Implementing equipment (including verification of operability), (4) Training, (5) SNF Project Technical Requirements (STRS) database system

  18. Potential dispositioning flowsheets for ICPP SNF and wastes

    Energy Technology Data Exchange (ETDEWEB)

    Olson, A.L. [ed.; Anderson, P.A.; Bendixsen, C.L. [and others

    1995-11-01

    The Idaho Chemical Processing Plant (ICPP), located at the Idaho National Laboratory (INEL), has reprocessed irradiated nuclear fuels for the US Department of Energy (DOE) since 1953. This activity resulted mainly in the recovery of uranium and the management of the resulting wastes. The acidic radioactive high-level liquid waste was routinely stored in stainless steel tanks and then calcined to form a dry granular solid. The calcine is stored in stainless steel bins that are housed in underground concrete vaults. In April 1992, the DOE discontinued the practice of reprocessing irradiated nuclear fuels. This decision has left a legacy of 1.8 million gallons of radioactive liquid wastes (1.5 million gallons of radioactive sodium-bearing liquid wastes and 0.3 million gallons of high-level liquid waste), 3800 cubic meters of calcine waste, and 289 metric tons of heavy metal within unprocessed spent nuclear fuel (SNF) left in inventory at the ICPP. The nation`s radioactive waste policy has been established by the Nuclear Waste Policy Act (NWPA), which requires the final disposal of SNF and radioactive waste in accordance with US Environmental Protection Agency (EPA) and Nuclear Regulatory Commission (NRC) standards. In accordance with these regulations and other legal agreements between the State of Idaho and the DOE, the DOE must, among other requirements, (1) complete a final Environmental Impact Statement by April 30, 1995, (2) evaluate and test sodium-bearing waste pre-treatment technologies, (3) select the sodium-bearing and calcine waste pre-treatment technology, if necessary, by June 1, 1995, and (4) select a technology for converting calcined waste into an appropriate disposal form by June 1, 1995.

  19. Potential dispositioning flowsheets for ICPP SNF and wastes

    International Nuclear Information System (INIS)

    Olson, A.L.; Anderson, P.A.; Bendixsen, C.L.

    1995-11-01

    The Idaho Chemical Processing Plant (ICPP), located at the Idaho National Laboratory (INEL), has reprocessed irradiated nuclear fuels for the US Department of Energy (DOE) since 1953. This activity resulted mainly in the recovery of uranium and the management of the resulting wastes. The acidic radioactive high-level liquid waste was routinely stored in stainless steel tanks and then calcined to form a dry granular solid. The calcine is stored in stainless steel bins that are housed in underground concrete vaults. In April 1992, the DOE discontinued the practice of reprocessing irradiated nuclear fuels. This decision has left a legacy of 1.8 million gallons of radioactive liquid wastes (1.5 million gallons of radioactive sodium-bearing liquid wastes and 0.3 million gallons of high-level liquid waste), 3800 cubic meters of calcine waste, and 289 metric tons of heavy metal within unprocessed spent nuclear fuel (SNF) left in inventory at the ICPP. The nation's radioactive waste policy has been established by the Nuclear Waste Policy Act (NWPA), which requires the final disposal of SNF and radioactive waste in accordance with US Environmental Protection Agency (EPA) and Nuclear Regulatory Commission (NRC) standards. In accordance with these regulations and other legal agreements between the State of Idaho and the DOE, the DOE must, among other requirements, (1) complete a final Environmental Impact Statement by April 30, 1995, (2) evaluate and test sodium-bearing waste pre-treatment technologies, (3) select the sodium-bearing and calcine waste pre-treatment technology, if necessary, by June 1, 1995, and (4) select a technology for converting calcined waste into an appropriate disposal form by June 1, 1995

  20. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Appendix I. Accident definition and use of event trees

    International Nuclear Information System (INIS)

    1975-10-01

    Information is presented concerning accident definition and use of event trees, event tree methodology, potential accidents covered by the reactor safety study, analysis of potential accidents involving the reactor core, and analysis of potential accidents not involving the core

  1. Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells

    Directory of Open Access Journals (Sweden)

    Brian McKenna

    2015-03-01

    Full Text Available Pdx1 is a transcription factor of fundamental importance to pancreas formation and adult islet β cell function. However, little is known about the positive- and negative-acting coregulators recruited to mediate transcriptional control. Here, we isolated numerous Pdx1-interacting factors possessing a wide range of cellular functions linked with this protein, including, but not limited to, coregulators associated with transcriptional activation and repression, DNA damage response, and DNA replication. Because chromatin remodeling activities are essential to developmental lineage decisions and adult cell function, our analysis focused on investigating the influence of the Swi/Snf chromatin remodeler on Pdx1 action. The two mutually exclusive and indispensable Swi/Snf core ATPase subunits, Brg1 and Brm, distinctly affected target gene expression in β cells. Furthermore, physiological and pathophysiological conditions dynamically regulated Pdx1 binding to these Swi/Snf complexes in vivo. We discuss how context-dependent recruitment of coregulatory complexes by Pdx1 could impact pancreas cell development and adult islet β cell activity.

  2. The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci.

    Directory of Open Access Journals (Sweden)

    Ana Neves-Costa

    2009-12-01

    Full Text Available Chromatin regulates many key processes in the nucleus by controlling access to the underlying DNA. SNF2-like factors are ATP-driven enzymes that play key roles in the dynamics of chromatin by remodelling nucleosomes and other nucleoprotein complexes. Even simple eukaryotes such as yeast contain members of several subfamilies of SNF2-like factors. The FUN30/ETL1 subfamily of SNF2 remodellers is conserved from yeasts to humans, but is poorly characterized. We show that the deletion of FUN30 leads to sensitivity to the topoisomerase I poison camptothecin and to severe cell cycle progression defects when the Orc5 subunit is mutated. We demonstrate a role of FUN30 in promoting silencing in the heterochromatin-like mating type locus HMR, telomeres and the rDNA repeats. Chromatin immunoprecipitation experiments demonstrate that Fun30 binds at the boundary element of the silent HMR and within the silent HMR. Mapping of nucleosomes in vivo using micrococcal nuclease demonstrates that deletion of FUN30 leads to changes of the chromatin structure at the boundary element. A point mutation in the ATP-binding site abrogates the silencing function of Fun30 as well as its toxicity upon overexpression, indicating that the ATPase activity is essential for these roles of Fun30. We identify by amino acid sequence analysis a putative CUE motif as a feature of FUN30/ETL1 factors and show that this motif assists Fun30 activity. Our work suggests that Fun30 is directly involved in silencing by regulating the chromatin structure within or around silent loci.

  3. Implications of the accident at Chernobyl for safety regulation of commercial nuclear power plants in the United Sates: Volume 2, Appendix - Public comments and their disposition: Final report

    International Nuclear Information System (INIS)

    1989-04-01

    This report was prepared by the Nuclear Regulatory Commission (NRC) staff to assess the implications of the accident at the Chernobyl nuclear power plant as they relate to reactor safety regulation for commercial nuclear power plants in the United States. The facts used in this assessment have been drawn from the US fact-finding report(NUREG-1250) and its sources. The general conclusions of the document are that there are generic lessons to be learned but that no changes in regulations are needed due to the substantial differences in the design, safety features and operation of US plants as compared to those in the USSR. Given these general conclusions, further consideration of certain specific areas is recommended by the report. These include: administrative controls over reactor regulation, reactivity accidents, accidents at low or zero power, multi-unit protection, fires, containment, emergency planning, severe accident phenomena, and graphite-moderated reactors

  4. Current status of development in dry pyro-electrochemical technology of SNF reprocessing

    International Nuclear Information System (INIS)

    Bychkov, A.V.; Skiba, O.V.; Kormilitsyn, M.V.

    2004-01-01

    The technology of SNF management in molten salts currently developed by a group of institutes headed by RIAR has had several stages of development: - basic research of uranium, plutonium and main FP properties (investigation and reprocessing of different kinds of SNF in 1960 - 1970); - development of the equipment and implementation of the pyro-electrochemical technology of granulated UPu fuel production. Development of the vibro-packing method and in-pile testing of vibro-packed fuel pins with granulated fuel as the most 'logical' continuation of reprocessing: implementation of the technology for BOR-60 and BN-600 (1980 - 1990); - development of closed fuel cycle elements. Checking of the technology using batches of SNF. In-pile tests. Feasibility study of the closed fuel cycle (CFC). Study of application of the technology to other objects (transmutation; nitride, cermet and other fuels) (1980 - 1990). The current status of the research is the following: - Basic research. Properties of uranium, plutonium, thorium, and neptunium in chloride melts have been studied in much detail. The data on physical chemistry and electrochemistry of the main FP is enough for understanding the processes. Detailed studies of americium, curium, and technetium chemistry are the essential investigation directions; - Engineering development. The technology and equipment bases have been developed for the processes of oxide fuel reprocessing and fabrication. The technology was checked using 5500 kg of pure fuel from different reactors and 20 kg of irradiated BN-350 and BOR-60 fuel. The bases of the technology have been provided and the feasibility study has been carried out for a full-scale plant of BN-800 CFC; - Industrial application: Since the technology is highly prepared, the activities on industrial application of U-Pu fuel are now underway. The BOR-60 reactor uses fuel obtained by the dry method, the design of the facility for implementation of CFC reactors is being developed. 9

  5. Development of the ENVI simulator to estimate Korean SNF flow and its cost - 16060

    International Nuclear Information System (INIS)

    Hwang, Yongsoo; Miller, Ian

    2009-01-01

    This paper describes an integrated model developed by the Korean Atomic Energy Research Institute (KAERI) to simulate options for managing spent nuclear fuel (SNF) in South Korea. A companion paper (Hwang and Miller, 2009) describes a performance assessment model to address the long-term safety of alternative geological disposal options for different waste streams. The model addresses alternative concepts for storage, transportation, and processing of SNF of different types (Candu, PWR), leading up to permanent disposal in geological repositories. It uses the GoldSim software to simulate the logistics of the associated activities, including the associated capital and operating costs. The model's results allow direct comparison of alternative waste management concepts, and predict the sizes and timings of different facilities required. Future versions of the model will also address the uncertainties associated with the different system components in order to provide risk-based assessments. (authors)

  6. Update to Assessment of Direct Disposal in Unsaturated Tuff of Spent Nuclear Fuel and High-Level Waste Owned by U.S. Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    P. D. Wheatley (INEEL POC); R. P. Rechard (SNL)

    1998-09-01

    The overall purpose of this study is to provide information and guidance to the Office of Environmental Management of the U.S. Department of Energy (DOE) about the level of characterization necessary to dispose of DOE-owned spent nuclear fuel (SNF). The disposal option modeled was codisposal of DOE SNF with defense high-level waste (DHLW). A specific goal was to demonstrate the influence of DOE SNF, expected to be minor, in a predominately commercial repository using modeling conditions similar to those currently assumed by the Yucca Mountain Project (YMP). A performance assessment (PA) was chosen as the method of analysis. The performance metric for this analysis (referred to as the 1997 PA) was dose to an individual; the time period of interest was 100,000 yr. Results indicated that cumulative releases of 99Tc and 237Np (primary contributors to human dose) from commercial SNF exceed those of DOE SNF both on a per MTHM and per package basis. Thus, if commercial SNF can meet regulatory performance criteria for dose to an individual, then the DOE SNF can also meet the criteria. This result is due in large part to lower burnup of the DOE SNF (less time for irradiation) and to the DOE SNF's small percentage of the total activity (1.5%) and mass (3.8%) of waste in the potential repository. Consistent with the analyses performed for the YMP, the 1997 PA assumed all cladding as failed, which also contributed to the relatively poor performance of commercial SNF compared to DOE SNF.

  7. Update to Assessment of Direct Disposal in Unsaturated Tuff of Spent Nuclear Fuel and High-Level Waste Owned by U.S. Department of Energy

    International Nuclear Information System (INIS)

    Wheatley, P.D.; Rechard, R.P.

    1998-01-01

    The overall purpose of this study is to provide information and guidance to the Office of Environmental Management of the U.S. Department of Energy (DOE) about the level of characterization necessary to dispose of DOE-owned spent nuclear fuel (SNF). The disposal option modeled was codisposal of DOE SNF with defense high-level waste (DHLW). A specific goal was to demonstrate the influence of DOE SNF, expected to be minor, in a predominately commercial repository using modeling conditions similar to those currently assumed by the Yucca Mountain Project (YMP). A performance assessment (PA) was chosen as the method of analysis. The performance metric for this analysis (referred to as the 1997 PA) was dose to an individual; the time period of interest was 100,000 yr. Results indicated that cumulative releases of 99Tc and 237Np (primary contributors to human dose) from commercial SNF exceed those of DOE SNF both on a per MTHM and per package basis. Thus, if commercial SNF can meet regulatory performance criteria for dose to an individual, then the DOE SNF can also meet the criteria. This result is due in large part to lower burnup of the DOE SNF (less time for irradiation) and to the DOE SNF's small percentage of the total activity (1.5%) and mass (3.8%) of waste in the potential repository. Consistent with the analyses performed for the YMP, the 1997 PA assumed all cladding as failed, which also contributed to the relatively poor performance of commercial SNF compared to DOE SNF

  8. SNF project's MCO compliance assessment with DOE ''general design criteria,'' order 6430.1A and ''SNF project MCO additional NRC requirements,'' HNF-SD-SNF-DB-005

    International Nuclear Information System (INIS)

    GOLDMANN, L.H.

    1999-01-01

    This document is presented to demonstrate the MCOs compliance to the major design criteria invoked on the MCO. This document is broken down into a section for the MCO's evaluation against DOE Order 6430.1A General Design Criteria sixteen divisions and then the evaluation of the MCO against HNF-SD-SNF-DB-005 ''Spent Nuclear Fuel Project Multi-Canister Overpack Additional NRC Requirements.'' The compliance assessment is presented as a matrix in tabular form. The MCO is the primary container for the K-basin's spent nuclear fuel as it leaves the basin pools and through to the 40 year interim storage at the Canister Storage Building (CSB). The MCO and its components interface with; the K basins, shipping cask and transportation system, Cold Vacuum Drying facility individual process bays and equipment, and CSB facility including the MCO handling machine (MHM), the storage tubes, and the MCO work stations where sampling, welding, and inspection of the MCO is performed. As the MCO is the primary boundary for handling, process, and storage, its main goals are to minimize the spread of its radiological contents to the outside of the MCO and provide for nuclear criticality control. The MCO contains personnel radiation shielding only on its upper end, in the form of a shield plug, where the process interfaces are located. Shielding beyond the shield plug is the responsibility of the using facilities. The design of the MCO and its components is depicted in drawings H-2-828040 through H-2-828075. Not every drawing number in the sequence is used. The first drawing number, H-2-828040, is the drawing index for the MCO. The design performance specification for the MCO is HW-S-0426, and was reviewed and approved by the interfacing design authorities, the safety, regulatory, and operations groups, and the local DOE office. The current revision for the design performance specification is revision 5. The designs of the MCO have been reviewed and approved in a similar way and the reports

  9. Airborne concentrations of radioactive materials in severe accidents

    International Nuclear Information System (INIS)

    Ross, D.F. Jr.; Denning, R.S.

    1989-01-01

    Radioactive materials would be released to the containment building of a commercial nuclear reactor during each of the stages of a severe accident. Results of analyses of two accident sequences are used to illustrate the magnitudes of these sources of radioactive materials, the resulting airborne mass concentrations, the characteristics of the airborne aerosols, the potential for vapor forms of radioactive materials, the effectiveness of engineered safety features in reducing airborne concentrations, and the release of radioactive materials to the environment. Ability to predict transport and deposition of radioactive materials is important to assessing the performance of containment safety features in severe accidents and in the development of accident management procedures to reduce the consequences of severe accidents

  10. Causal factors in accidents of high-speed craft and conventional ocean-going vessels

    International Nuclear Information System (INIS)

    Antao, Pedro; Guedes Soares, C.

    2008-01-01

    An analysis of 40 ocean-going commercial vessel accidents is compared with the study of a similar number of high-speed crafts (HSCs) accidents, using in both cases a methodology that highlights the sequence of events leading to the accident and identifies the associated latent or causal factors. The main objective of this study was to identify and understand the difference in the pattern of causal factors associated with HSC accidents, as compared with the more traditional ocean-going ships. From the analysis one can see that the HSC accidents are mainly related to bridge personnel and operations, where the human element is the key factor identified as being responsible for the majority of the accidents. When compared with ocean-going commercial vessels, it is clear that navigational equipment and procedures have a larger preponderance in terms of the occurrence of accidents of HSC and particular attention should be given to these issues

  11. HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A

    International Nuclear Information System (INIS)

    Van Rechem, Capucine; Boulay, Gaylor; Leprince, Dominique

    2009-01-01

    HIC1, a tumor suppressor gene epigenetically silenced in many human cancers encodes a transcriptional repressor involved in regulatory loops modulating p53-dependent and E2F1-dependent cell survival and stress responses. HIC1 is also implicated in growth control since it recruits BRG1, one of the two alternative ATPases (BRM or BRG1) of SWI/SNF chromatin-remodeling complexes to repress transcription of E2F1 in quiescent fibroblasts. Here, through yeast two-hybrid screening, we identify ARID1A/BAF250A, as a new HIC1 partner. ARID1A/BAF250A is one of the two mutually exclusive ARID1-containing subunits of SWI/SNF complexes which define subsets of complexes endowed with anti-proliferative properties. Co-immunoprecipitation assays in WI38 fibroblasts and in BRG1-/- SW13 cells showed that endogenous HIC1 and ARID1A proteins interact in a BRG1-dependent manner. Furthermore, we demonstrate that HIC1 does not interact with BRM. Finally, sequential chromatin immunoprecipitation (ChIP-reChIP) experiments demonstrated that HIC1 represses E2F1 through the recruitment of anti-proliferative SWI/SNF complexes containing ARID1A.

  12. SNF/HLW Transfer System Description Document

    International Nuclear Information System (INIS)

    W. Holt

    2005-01-01

    The purpose of this system description document (SDD) is to establish requirements that drive the design of the spent nuclear fuel (SNF)/high-level radioactive waste (HLW) transfer system and associated bases, which will allow the design effort to proceed to license application. This SDD will be revised at strategic points as the design matures. This SDD identifies the requirements and describes the system design, as it currently exists, with emphasis on attributes of the design provided to meet the requirements. This SDD is an engineering tool for design control. Accordingly, the primary audience and users are design engineers. This SDD is part of an iterative design process. It leads the design process with regard to the flowdown of upper tier requirements onto the system. Knowledge of these requirements is essential in performing the design process. The SDD follows the design with regard to the description of the system. The description provided in this SDD reflects the current results of the design process

  13. A Green Approach to SNF Reprocessing: Are Common Household Reagents the Answer?

    International Nuclear Information System (INIS)

    Peper, Shane M.; McNamara, Bruce K.; O'Hara, Matthew J.; Douglas, Matthew

    2008-01-01

    It has been discovered that UO2, the principal component of spent nuclear fuel (SNF), can efficiently be dissolved at room temperature using a combination of common household reagents, namely hydrogen peroxide, baking soda, and ammonia. This rather serendipitous discovery opens up the possibility, for the first time, of considering a non-acidic process for recycling U from SNF. Albeit at the early stages of development, our unconventional dissolution approach possesses many attractive features that could make it a reality in the future. With dissolution byproducts of water and oxygen, our approach poses a minimal threat to the environment. Moreover, the use of common household reagents to afford actinide oxide dissolution suggests a certain degree of economic favorability. With the use of a ''closed'' digestion vessel as a reaction chamber, our approach has substantial versatility with the option of using either aqueous or gaseous reactant feeds or a combination of both. Our approach distinguishes itself from all existing reprocessing technologies in two important ways. First and foremost, it is an alkaline rather than an acidic process, using mild non-corrosive chemicals under ambient conditions to effect actinide separations. Secondly, it does not dissolve the entire SNF matrix, but rather selectively solubilizes U and other light actinides for subsequent separation, resulting in potentially faster head-end dissolution and fewer downstream separation steps. From a safeguards perspective, the use of oxidizing alkaline solutions to effect actinide separations also potentially offers a degree of inherent proliferation resistance, by allowing the U to be selectively removed from the remaining dissolver solution while keeping Pu grouped with the other minor actinides and fission products. This paper will describe the design and general experimental setup of a 'closed' digestion vessel for performing uranium oxide dissolutions under alkaline conditions using gaseous

  14. A Green Approach to SNF Reprocessing: Are Common Household Reagents the Answer?

    Energy Technology Data Exchange (ETDEWEB)

    Peper, Shane M.; McNamara, Bruce K.; O' Hara, Matthew J.; Douglas, Matthew

    2008-04-03

    It has been discovered that UO2, the principal component of spent nuclear fuel (SNF), can efficiently be dissolved at room temperature using a combination of common household reagents, namely hydrogen peroxide, baking soda, and ammonia. This rather serendipitous discovery opens up the possibility, for the first time, of considering a non-acidic process for recycling U from SNF. Albeit at the early stages of development, our unconventional dissolution approach possesses many attractive features that could make it a reality in the future. With dissolution byproducts of water and oxygen, our approach poses a minimal threat to the environment. Moreover, the use of common household reagents to afford actinide oxide dissolution suggests a certain degree of economic favorability. With the use of a “closed” digestion vessel as a reaction chamber, our approach has substantial versatility with the option of using either aqueous or gaseous reactant feeds or a combination of both. Our approach distinguishes itself from all existing reprocessing technologies in two important ways. First and foremost, it is an alkaline rather than an acidic process, using mild non-corrosive chemicals under ambient conditions to effect actinide separations. Secondly, it does not dissolve the entire SNF matrix, but rather selectively solubilizes U and other light actinides for subsequent separation, resulting in potentially faster head-end dissolution and fewer downstream separation steps. From a safeguards perspective, the use of oxidizing alkaline solutions to effect actinide separations also potentially offers a degree of inherent proliferation resistance, by allowing the U to be selectively removed from the remaining dissolver solution while keeping Pu grouped with the other minor actinides and fission products. This paper will describe the design and general experimental setup of a “closed” digestion vessel for performing uranium oxide dissolutions under alkaline conditions using

  15. Problems and solutions of the spent nuclear fuel (SNF) at Kozloduy NPP

    International Nuclear Information System (INIS)

    Jordanov, J.

    2003-01-01

    There are two options concerning spent nuclear fuel: to return it back to Russia for reprocessing or to store it on the site until we decide what to do with it. In both options prior to the shutting down of each reactor the Spent Fuel Pool thereto should be vacated (the filling in of the equipment at present is illustrated) and the Spent Fuel Storage Facility (SFSF) should also be vacated after the stop of the last nuclear facility on the site in order to be reequipped for permanent storage of the highly active wastes which will be returned in the country, if we submit the fuel for reprocessing; or of SNF, if we decide to leave them ultimately in Bulgaria. The difference is mainly in the quantities which will permanently remain here, respectively the volumes required for their storage and the funds necessary for the implementation of the processes. The pool volumes filling in both variants is also illustrated and the SFSF will be filled by 2008, if no fuel is transported.Costs of the SNF transport to Russia and investment costs of dry storage of SNF from pools 1 - 4 are present. The costs are visibly lower compared to those in the case of return of the fuel. However, these are only investments for construction and equipment of the buildings and storage containers. The costs related to their servicing are not included, and it should be taken into account that in approximately 50 years we will have to seek solution for their permanent storage. Despite the material costs to be incurred now for the implementation of the option with the return of the fuel, this is the more worthy way to resolve the problem. In accordance with the ethic principles in the nuclear energy, the burdens arising as a result of the use of nuclear facilities should be covered by the generation consuming the benefits from it

  16. Risks of potential accidents of nuclear power plants in Europe

    NARCIS (Netherlands)

    Slaper H; Eggink GJ; Blaauboer RO

    1993-01-01

    Over 200 nuclear power plants for commercial electricity production are presently operational in Europe. The 1986 accident with the nuclear power plant in Chernobyl has shown that severe accidents with a nuclear power plant can lead to a large scale contamination of Europe. This report is focussed

  17. Biallelic germline and somatic mutations in malignant mesothelioma: multiple mutations in transcription regulators including mSWI/SNF genes.

    Science.gov (United States)

    Yoshikawa, Yoshie; Sato, Ayuko; Tsujimura, Tohru; Otsuki, Taiichiro; Fukuoka, Kazuya; Hasegawa, Seiki; Nakano, Takashi; Hashimoto-Tamaoki, Tomoko

    2015-02-01

    We detected low levels of acetylation for histone H3 tail lysines in malignant mesothelioma (MM) cell lines resistant to histone deacetylase inhibitors. To identify the possible genetic causes related to the low histone acetylation levels, whole-exome sequencing was conducted with MM cell lines established from eight patients. A mono-allelic variant of BRD1 was common to two MM cell lines with very low acetylation levels. We identified 318 homozygous protein-damaging variants/mutations (18-78 variants/mutations per patient); annotation analysis showed enrichment of the molecules associated with mammalian SWI/SNF (mSWI/SNF) chromatin remodeling complexes and co-activators that facilitate initiation of transcription. In seven of the patients, we detected a combination of variants in histone modifiers or transcription factors/co-factors, in addition to variants in mSWI/SNF. Direct sequencing showed that homozygous mutations in SMARCA4, PBRM1 and ARID2 were somatic. In one patient, homozygous germline variants were observed for SMARCC1 and SETD2 in chr3p22.1-3p14.2. These exhibited extended germline homozygosity and were in regions containing somatic mutations, leading to a loss of BAP1 and PBRM1 expression in MM cell line. Most protein-damaging variants were heterozygous in normal tissues. Heterozygous germline variants were often converted into hemizygous variants by mono-allelic deletion, and were rarely homozygous because of acquired uniparental disomy. Our findings imply that MM might develop through the somatic inactivation of mSWI/SNF complex subunits and/or histone modifiers, including BAP1, in subjects that have rare germline variants of these transcription regulators and/or transcription factors/co-factors, and in regions prone to mono-allelic deletion during oncogenesis. © 2014 UICC.

  18. Chernobyl reactor accident

    International Nuclear Information System (INIS)

    Malinauskas, A.P.; Buchanan, J.R.; Lorenz, R.A.; Yamashita, T.

    1986-01-01

    On April 26, 1986, an explosion occurred at the newest of four operating nuclear reactors at the Chernobyl site in the USSR. The accident initiated an international technical exchange of almost unprecedented magnitude; this exchange was climaxed with a meeting at the International Atomic Energy Agency in Vienna during the week of August 25, 1986. The meeting was attended by more than 540 official representatives from 51 countries and 20 international organizations. Information gleaned from that technical exchange is presented in this report. A description of the Chernobyl reactor, which differs significantly from commercial US reactors, is presented, the accident scenario advanced by the Russian delegation is discussed, and observations that have been made concerning fission product release are described

  19. Incidence of road traffic accidents and pattern of injury among ...

    African Journals Online (AJOL)

    Background and Objective: Motorcyclists are at high risk of road traffic accidents and the attendant injuries, but few community-based studies have investigated the problem in Nigeria. Therefore, this study was conducted to determine the incidence of accidents and patterns of non-fatal injury among commercial motorcyclists ...

  20. Pattern of injuries from motorcycle accidents in Abia State, Nigeria ...

    African Journals Online (AJOL)

    Background: Motorcycle accidents are very common and cause major injuries. The Abia State government banned commercial motorcyclists from operating in the major cities of the state in July, 2009. Objectives: To determine the influence of this ban on the cause and pattern of injuries due to road traffic accidents. Design: ...

  1. Retention of elemental 131I by activated carbons under accident conditions

    International Nuclear Information System (INIS)

    Deuber, H.

    1984-09-01

    Under simulated accident conditions (maximum temperature: 130 0 C) no significant difference was found in the retention of I-131 loaded as elemental iodine, by various fresh and aged commercial activated carbons. In all the cases, the I-131 passing through deep beds of activated carbon was in a non-elemental form. It is concluded that a minimum retention of 99.99% for elemental radioiodine, as required by the RSK guidelines for PWR accident filters, can be equally well achieved with various commercial activated carbons. (orig.) [de

  2. Interaction of DOE SNF and Packaging Materials

    International Nuclear Information System (INIS)

    Anderson, P.A.

    1998-01-01

    A sensitivity analysis was conducted to identify and evaluate potential destructive interactions between the materials in US Department of Energy (USDOE) spent nuclear fuels (SNFs) and their storage/disposal canisters. The technical assessment was based on the thermodynamic properties as well as the chemical and physical characteristics of the materials expected inside the canisters. No chemical reactions were disclosed that could feasibly corrode stainless steel canisters to the point of failure. However, the possibility of embrittlement (loss of ductility) of the stainless steel through contact with liquid metal fission products or hydrogen inside the canisters cannot be dismissed. Higher-than-currently-permitted internal gas pressures must also be considered. These results, based on the assessment of two representative 90-year-cooled fuels that are stored at 200C in stainless steel canisters with internal blankets of helium, may be applied to most of the fuels in the USDOE's SNF inventory

  3. Human Error and General Aviation Accidents: A Comprehensive, Fine-Grained Analysis Using HFACS

    National Research Council Canada - National Science Library

    Wiegmann, Douglas; Faaborg, Troy; Boquet, Albert; Detwiler, Cristy; Holcomb, Kali; Shappell, Scott

    2005-01-01

    ... of both commercial and general aviation (GA) accidents. These analyses have helped to identify general trends in the types of human factors issues and aircrew errors that have contributed to civil aviation accidents...

  4. A Multi-function Cask for At-Reactor Storage of Short-Cooled Spent Fuel, Transport, and Disposal

    International Nuclear Information System (INIS)

    Forsberg, C.W.

    2004-01-01

    The spent nuclear fuel (SNF) system in the United States was designed with the assumptions that SNF would be stored for several years in an at-reactor pool and then transported to reprocessing plants for recovery of fissile materials, that security would not be a major issue, and that the SNF burnups would be low. The system has evolved into a once-through fuel cycle with high-burnup SNF, long-term storage at the reactor sites, and major requirements for safeguards and security. An alternative system is proposed to better meet these current requirements. The SNF is placed in multi-function casks with the casks used for at-reactor storage, transport, and repository disposal. The cask is the handling package, provides radiation shielding, and protects the SNF against accidents and assault. SNF assemblies are handled only once to minimize accident risks, maximize security and safeguards by minimizing access to SNF, and reduce costs. To maximize physical protection, the cask body is constructed of a cermet (oxide particles embedded in steel, the same class of materials used in tank armor) and contains no cooling channels or other penetrations that allow access to the SNF. To minimize pool storage of SNF, the cask is designed to accept short-cooled SNF. To maximize the capability of the cask to reject decay heat and to limit SNF temperatures from short-cooled SNF, the cask uses (1) natural circulation of inert gas mixtures inside the cask to transfer heat from the SNF to the cask body and (2) an overpack with external natural-circulation, liquid-cooled fins to transfer heat from the cask body to the atmosphere. This approach utilizes the entire cask body area for heat transfer to maximize heat removal rates-without any penetrations through the cask body that would reduce the physical protection capabilities of the cask body. After the SNF has cooled, the cooling overpack is removed. At the repository, the cask is placed in a corrosion-resistant overpack before disposal

  5. Market driven strategy for acquisition of waste acceptance and transportation services for commercial spent fuel in the united states

    International Nuclear Information System (INIS)

    Lemeshewsky, W.; Macaluso, C.; Smith, P.; Teer, B.

    1998-01-01

    The Office of Civilian Radioactive Waste Management (OCRWM) in the United States Department of Energy (DOE) has the responsibility under the Nuclear Waste Policy Act of 1982 (the Act) for the shipment of spent nuclear fuel (SNF) from commercial reactors to a Federal facility for storage and/or disposal. The Act requires the use of private industry to the 'fullest extent possible' in the transportation of spent fuels. An OCRWM goal is to develop a safe, efficient and effective transportation system while meeting the mandate of the Act. OCRWM has then develop a strategy for a market driven approach for the acquisition of transportation services and equipment. To implement this strategy, OCRWM is planning to issue a Request for Proposal (RPF) for the provision of the required services and equipment to accept SNF from the utilities and transport the SNF to a Federal facility. Two draft RPFs have been issued with the second draft incorporating comments on the first draft from potential contractors and other interested parties. The overall strategy as outlined in the draft RPF relies on private industry to use the innovative powers of the marketplace to help DOE accomplish its mission objectives. DOE intends to pursue this procurement strategy whether or not the OCRWM program includes interim storage. The concept described in the draft RPF provides for DOE to purchase services and equipment from a contractor-operated waste acceptance and transportation organization. The contractor is expected to provide initial financing for the project including that necessary for initial acquisition of operational equipment, establish the necessary management organization, and mobilize the necessary resources and capabilities to provide the SNF delivery services at a fixed rate. DOE will retain final approval on all routes and maintain primary responsibility to the States, tribes, and local units of government for assuring appropriate interaction and consideration of their input on

  6. Rhabdoid and Undifferentiated Phenotype in Renal Cell Carcinoma: Analysis of 32 Cases Indicating a Distinctive Common Pathway of Dedifferentiation Frequently Associated With SWI/SNF Complex Deficiency.

    Science.gov (United States)

    Agaimy, Abbas; Cheng, Liang; Egevad, Lars; Feyerabend, Bernd; Hes, Ondřej; Keck, Bastian; Pizzolitto, Stefano; Sioletic, Stefano; Wullich, Bernd; Hartmann, Arndt

    2017-02-01

    Undifferentiated (anaplastic) and rhabdoid cell features are increasingly recognized as adverse prognostic findings in renal cell carcinoma (RCC), but their molecular pathogenesis has not been studied sufficiently. Recent studies identified alterations in the Switch Sucrose nonfermentable (SWI/SNF) chromatin remodeling complex as molecular mechanisms underlying dedifferentiation and rhabdoid features in carcinomas of different organs. We herein have analyzed 32 undifferentiated RCCs having in common an undifferentiated (anaplastic) phenotype, prominent rhabdoid features, or both, irrespective of the presence or absence of conventional RCC component. Cases were stained with 6 SWI/SNF pathway members (SMARCB1, SMARCA2, SMARCA4, ARID1A, SMARCC1, and SMARCC2) in addition to conventional RCC markers. Patients were 20 males and 12 females aged 32 to 85 years (mean, 59). A total of 22/27 patients with known stage presented with ≥pT3. A differentiated component varying from microscopic to major component was detected in 20/32 cases (16 clear cell and 2 cases each chromophobe and papillary RCC). The undifferentiated component varied from rhabdoid dyscohesive cells to large epithelioid to small monotonous anaplastic cells. Variable loss of at least 1 SWI/SNF complex subunit was noted in the undifferentiated/rhabdoid component of 21/32 cases (65%) compared with intact or reduced expression in the differentiated component. A total of 15/17 patients (88%) with follow-up died of metastatic disease (mostly within 1 y). Only 2 patients were disease free at last follow-up (1 and 6 y). No difference in survival, age distribution, or sex was observed between the SWI/SNF-deficient and the SWI/SNF-intact group. This is the first study exploring the role of SWI/SNF deficiency as a potential mechanism underlying undifferentiated and rhabdoid phenotype in RCC. Our results highlight the association between the aggressive rhabdoid phenotype and the SWI/SNF complex deficiency, consistent

  7. Licensing decisions and safety research related to LMFBR accidents

    International Nuclear Information System (INIS)

    Denise, R.P.; Speis, T.P.; Kelber, C.N.; Curtis, R.T.

    1977-01-01

    The licensing approach which ensures adequate protection of the public health and safety against serious accidents is described. This paper describes the role of core melt and core disruptive accidents in the design, safety research, and licensing processes, using the Clinch River Breeder Reactor (CRBR) as a focal point. Major design attention is placed on the prevention of these accidents so that the probability of core melt accidents is reduced to a sufficiently low level that they are not treated as design basis accidents. Additional requirements are placed upon the design to further reduce residual risk. This licensing process is supported by a confirmatory research program designed to provide an independent basis for licensing judgements. It has as a goal the resolution of generic safety issues prior to the establishment of a commercial LMFBR industry. The program includes accident analysis, experiments in materials interactions, aerosol transport and system integrity and planning for new safety test facilities. The problems are approached in a multi-disciplinary functional manner that identifies key safety issues and centralizes efforts to resolve them. The near term objectives of the program support the licensing of the Clinch River Breeder Reactor (CRBR) and the proposed Prototype Large Breeder Reactor (PLBR). The long term objectives of the program support the licensing of commercial LMFBRs during the late 1980's and beyond. This safety research is designed to provide an independent basis for the licensing judgements which must be made by the Nuclear Regulatory Commission

  8. Full-length fuel rod behavior under severe accident conditions

    International Nuclear Information System (INIS)

    Lombardo, N.J.; Lanning, D.D.; Panisko, F.E.

    1992-12-01

    This document presents an assessment of the severe accident phenomena observed from four Full-Length High-Temperature (FLHT) tests that were performed by the Pacific Northwest Laboratory (PNL) in the National Research Universal (NRU) reactor at Chalk River, Ontario, Canada. These tests were conducted for the US Nuclear Regulatory Commission (NRC) as part of the Severe Accident Research Program. The objectives of the test were to simulate conditions and provide information on the behavior of full-length fuel rods during hypothetical, small-break, loss-of-coolant severe accidents, in commercial light water reactors

  9. A cost effective approach for criticality accident analysis of a DOE SNF storage facility

    International Nuclear Information System (INIS)

    Garrett, R.L.; Couture, G.F.; Gough, S.T.

    1997-01-01

    This paper presents the methodologies used to derive criticality accident analyses for a spent nuclear fuel receipt, storage, handling, and shipping facility. Two criticality events are considered: process-induced and Natural Phenomena Hazards (NPH)-induced. The criticality analyses required the development of: (1) the frequency at which each sceanario occurred, (2) the estimated number of fissions for each scenario, and (3) the consequences associated with each criticality scenario. A fault tree analysis was performed to quantify the frequency of criticality due to process-induced events. For the frequency analysis of NPH-induced criticality, a probabilistic approach was employed. To estimate the consequences of a criticality event, the resulting fission yield was determined using a probabilistic approach. For estimating the source term, a 95% amount of overall conservatism was targeted. This methodology applied to the facility criticality scenarios indicated that: (1) the 95th percentile yield levels from the historical yield distributions are approximately 5 x 10 17 fissions and 5 x 10 18 fissions for internal event and NPH-induced criticality event, respectively; and (2) using probabilistic Latin Hypercube Sampling, the downwind 95th percentile dose to a receptor at the US DOE reservation boundary is 2.2 mrem. This estimate is compared to the bounding dose of 1.4 rem. 4 refs., 1 fig

  10. The handling of radiation accidents

    International Nuclear Information System (INIS)

    1977-01-01

    The symposium was attended by 204 participants from 39 countries and 5 international organizations. Forty-two papers were presented in 8 sessions. The purpose of the meeting was to foster an exchange of experiences gained in establishing and exercising plans for mitigating the effects of radiation accidents and in the handling of actual accident situations. Only a small number of accidents were reported at the symposium, and this reflects the very high standards of safety that has been achieved by the nuclear industry. No accidents of radiological significance were reported to have occurred at commercial nuclear power plants. Of the accidents reported, industrial radiography continues to be the area in which most of the radiation accidents occur. The experience gained in the reported accident situations served to confirm the crucial importance of the prompt availability of medical and radiological services, particularly in the case of uptake of radioactive material, and emphasized the importance of detailed investigation into the causes of the accident in order to improve preventative measures. One of the principal themes of the symposium involved emergency procedures related to nuclear power plant accidents, and several papers defining the scope, progression and consequences of design base accidents for both thermal and fast reactor systems were presented. These were complemented by papers defining the resultant protection requirements that should be satisfied in the establishment of plans designed to mitigate the effects of the postulated accident situations. Several papers were presented describing existing emergency organizational arrangements relating both to specific nuclear power plants and to comprehensive national schemes, and a particularly informative session was devoted to the topic of training of personnel in the practical conduct of emergency arrangements. The general feeling of the participants was one of studied confidence in the competence and

  11. Accidents - Chernobyl accident; Accidents - accident de Tchernobyl

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This file is devoted to the Chernobyl accident. It is divided in four parts. The first part concerns the accident itself and its technical management. The second part is relative to the radiation doses and the different contaminations. The third part reports the sanitary effects, the determinists ones and the stochastic ones. The fourth and last part relates the consequences for the other European countries with the case of France. Through the different parts a point is tackled with the measures taken after the accident by the other countries to manage an accident, the cooperation between the different countries and the groups of research and studies about the reactors safety, and also with the international medical cooperation, specially for the children, everything in relation with the Chernobyl accident. (N.C.)

  12. A Safety Case Approach for Deep Geologic Disposal of DOE HLW and DOE SNF in Bedded Salt - 13350

    Energy Technology Data Exchange (ETDEWEB)

    Sevougian, S. David [Advanced Nuclear Energy Programs Group, Sandia National Laboratories, P.O. Box 5800, Albuquerque, NM 87185 (United States); MacKinnon, Robert J. [Advanced Nuclear Energy Programs Group, Sandia National Laboratories, P.O. Box 5800, Albuquerque, NM 87185 (United States); Leigh, Christi D. [Defense Waste Management Programs Group, Sandia National Laboratories, P.O. Box 5800, Albuquerque, NM 87185 (United States); Hansen, Frank D. [Geoscience Research and Applications Group, Sandia National Laboratories, P.O. Box 5800, Albuquerque, NM 87185 (United States)

    2013-07-01

    The primary objective of this study is to investigate the feasibility and utility of developing a defensible safety case for disposal of United States Department of Energy (U.S. DOE) high-level waste (HLW) and DOE spent nuclear fuel (SNF) in a conceptual deep geologic repository that is assumed to be located in a bedded salt formation of the Delaware Basin [1]. A safety case is a formal compilation of evidence, analyses, and arguments that substantiate and demonstrate the safety of a proposed or conceptual repository. We conclude that a strong initial safety case for potential licensing can be readily compiled by capitalizing on the extensive technical basis that exists from prior work on the Waste Isolation Pilot Plant (WIPP), other U.S. repository development programs, and the work published through international efforts in salt repository programs such as in Germany. The potential benefits of developing a safety case include leveraging previous investments in WIPP to reduce future new repository costs, enhancing the ability to effectively plan for a repository and its licensing, and possibly expediting a schedule for a repository. A safety case will provide the necessary structure for organizing and synthesizing existing salt repository science and identifying any issues and gaps pertaining to safe disposal of DOE HLW and DOE SNF in bedded salt. The safety case synthesis will help DOE to plan its future R and D activities for investigating salt disposal using a risk-informed approach that prioritizes test activities that include laboratory, field, and underground investigations. It should be emphasized that the DOE has not made any decisions regarding the disposition of DOE HLW and DOE SNF. Furthermore, the safety case discussed herein is not intended to either site a repository in the Delaware Basin or preclude siting in other media at other locations. Rather, this study simply presents an approach for accelerated development of a safety case for a potential

  13. A Safety Case Approach for Deep Geologic Disposal of DOE HLW and DOE SNF in Bedded Salt - 13350

    International Nuclear Information System (INIS)

    Sevougian, S. David; MacKinnon, Robert J.; Leigh, Christi D.; Hansen, Frank D.

    2013-01-01

    The primary objective of this study is to investigate the feasibility and utility of developing a defensible safety case for disposal of United States Department of Energy (U.S. DOE) high-level waste (HLW) and DOE spent nuclear fuel (SNF) in a conceptual deep geologic repository that is assumed to be located in a bedded salt formation of the Delaware Basin [1]. A safety case is a formal compilation of evidence, analyses, and arguments that substantiate and demonstrate the safety of a proposed or conceptual repository. We conclude that a strong initial safety case for potential licensing can be readily compiled by capitalizing on the extensive technical basis that exists from prior work on the Waste Isolation Pilot Plant (WIPP), other U.S. repository development programs, and the work published through international efforts in salt repository programs such as in Germany. The potential benefits of developing a safety case include leveraging previous investments in WIPP to reduce future new repository costs, enhancing the ability to effectively plan for a repository and its licensing, and possibly expediting a schedule for a repository. A safety case will provide the necessary structure for organizing and synthesizing existing salt repository science and identifying any issues and gaps pertaining to safe disposal of DOE HLW and DOE SNF in bedded salt. The safety case synthesis will help DOE to plan its future R and D activities for investigating salt disposal using a risk-informed approach that prioritizes test activities that include laboratory, field, and underground investigations. It should be emphasized that the DOE has not made any decisions regarding the disposition of DOE HLW and DOE SNF. Furthermore, the safety case discussed herein is not intended to either site a repository in the Delaware Basin or preclude siting in other media at other locations. Rather, this study simply presents an approach for accelerated development of a safety case for a potential

  14. Confirmation of an ARID2 defect in SWI/SNF-related intellectual disability.

    Science.gov (United States)

    Van Paemel, Ruben; De Bruyne, Pauline; van der Straaten, Saskia; D'hondt, Marleen; Fränkel, Urlien; Dheedene, Annelies; Menten, Björn; Callewaert, Bert

    2017-11-01

    We present a 4-year-old girl with delayed neuromotor development, short stature of prenatal onset, and specific behavioral and craniofacial features harboring an intragenic deletion in the ARID2 gene. The phenotype confirmed the major features of the recently described ARID2-related intellectual disability syndrome. However, our patient showed overlapping features with Nicolaides-Baraitser syndrome and Coffin-Siris syndrome, providing further arguments to reclassify these disorders as "SWI/SNF-related intellectual disability syndromes." © 2017 Wiley Periodicals, Inc.

  15. Radionuclide Inventories for DOE SNF Waste Stream and Uranium/Thorium Carbide Fuels

    International Nuclear Information System (INIS)

    K.L. Goluoglu

    2000-01-01

    The objective of this calculation is to generate radionuclide inventories for the Department of Energy (DOE) spent nuclear fuel (SNF) waste stream destined for disposal at the potential repository at Yucca Mountain. The scope of this calculation is limited to the calculation of two radionuclide inventories; one for all uranium/thorium carbide fuels in the waste stream and one for the entire waste stream. These inventories will provide input in future screening calculations to be performed by Performance Assessment to determine important radionuclides

  16. A Content Analysis of News Media Coverage of the Accident at Three Mile Island.

    Science.gov (United States)

    Stephens, Mitchell; Edison, Nadyne G.

    A study was conducted for the President's Commission on the Accident at Three Mile Island to analyze coverage of the accident by ten news organizations: two wire services, three commercial television networks, and five daily newspapers. Copies of all stories and transcripts of news programs during the first week of the accident were examined from…

  17. SNF Interim Storage Canister Corrosion and Surface Environment Investigations

    International Nuclear Information System (INIS)

    Bryan, Charles R.; Enos, David G.

    2015-01-01

    This progress report describes work being done at Sandia National Laboratories (SNL) to assess the localized corrosion performance of container/cask materials used in the interim storage of spent nuclear fuel (SNF). Of particular concern is stress corrosion cracking (SCC), by which a through-wall crack could potentially form in a canister outer wall over time intervals that are shorter than possible dry storage times. In order for SCC to occur, three criteria must be met. A corrosive environment must be present on the canister surface, the metal must susceptible to SCC, and sufficient tensile stress to support SCC must be present through the entire thickness of the canister wall. SNL is currently evaluating the potential for each of these criteria to be met.

  18. SNF Interim Storage Canister Corrosion and Surface Environment Investigations

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Charles R. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Enos, David G. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    This progress report describes work being done at Sandia National Laboratories (SNL) to assess the localized corrosion performance of container/cask materials used in the interim storage of spent nuclear fuel (SNF). Of particular concern is stress corrosion cracking (SCC), by which a through-wall crack could potentially form in a canister outer wall over time intervals that are shorter than possible dry storage times. In order for SCC to occur, three criteria must be met. A corrosive environment must be present on the canister surface, the metal must susceptible to SCC, and sufficient tensile stress to support SCC must be present through the entire thickness of the canister wall. SNL is currently evaluating the potential for each of these criteria to be met.

  19. Assessment of WWER fuel condition in design basis accident

    International Nuclear Information System (INIS)

    Bibilashvili, Yu.; Sokolov, N.; Andreeva-Andrievskaya, L.; Vlasov, Yu.; Nechaeva, O.; Salatov, A.

    1994-01-01

    The fuel behaviour in design basis accidents is assessed by means of the verified code RAPTA-5. The code uses a set of high temperature physico-chemical properties of the fuel components as determined for commercially produced materials, fuel rod simulators and fuel rod bundles. The WWER fuel criteria available in Russia for design basis accidents do not generally differ from the similar criteria adopted for PWR's. 12 figs., 11 refs

  20. Assessment of the accident response of a light-water-moderated breeder-reactor system: AWBA development program

    International Nuclear Information System (INIS)

    High, H.M.

    1983-05-01

    The predicted accident response for a light water moderated, thorium/U-233 fueled, seed-blanket reactor concept was assessed. The first part of the assessment compared breeder accident response with that of a current commercial pressurized water reactor design for several different types of transients. Based on these comparisons and a review of the various parameter differences between the breeder and a U-235 fueled plant, the second part of the assessment studied the breeder accident behavior in more detail, particularly in areas of potential concern. Based on the two parts of the assessment, it was concluded that the breeder accident response would be very similar to that of present commercial pressurized water reactor plants. The large Doppler and moderator reactivity coefficients of the breeder would significantly reduce the severity of many of the accidents that must be considered. It is expected that the accident response of the breeder can be shown to meet regulatory criteria

  1. The impact of traffic sign deficit on road traffic accidents in Nigeria.

    Science.gov (United States)

    Ezeibe, Christian; Ilo, Chukwudi; Oguonu, Chika; Ali, Alphonsus; Abada, Ifeanyi; Ezeibe, Ezinwanne; Oguonu, Chukwunonso; Abada, Felicia; Izueke, Edwin; Agbo, Humphrey

    2018-04-04

    This study assesses the impact of traffic sign deficit on road traffic accidents in Nigeria. The participants were 720 commercial vehicle drivers. While simple random sampling was used to select 6 out of 137 federal highways, stratified random sampling was used to select six categories of commercial vehicle drivers. The study used qual-dominant mixed methods approach comprising key informant interviews; group interviews; field observation; policy appraisal and secondary literature on traffic signs. Result shows that the failure of government to provide and maintain traffic signs in order to guide road users through the numerous accident black spots on the highways is the major cause of road accidents in Nigeria. The study argues that provision and maintenance of traffic signs present opportunity to promoting safety on the highways and achieving the sustainable development goals.

  2. Road Traffic Accidents In Uyo Urban, Akwa Ibom State: The Scourge ...

    African Journals Online (AJOL)

    The aim was to determnie the scope of Road Traffic accidents in Uyo Urban, the hub of Akwa Ibom State commercial life, the role of motor cycles in the mishaps, the nature of trauma sustained; the bones commonly involved and the possible causes of the accidents: The data obtained, showed that motor cycles are involved ...

  3. Assessment of WWER fuel condition in design basis accident

    Energy Technology Data Exchange (ETDEWEB)

    Bibilashvili, Yu; Sokolov, N; Andreeva-Andrievskaya, L; Vlasov, Yu; Nechaeva, O; Salatov, A [Vsesoyuznyj Nauchno-Issledovatel` skij Inst. Neorganicheskikh Materialov, Moscow (Russian Federation)

    1994-12-31

    The fuel behaviour in design basis accidents is assessed by means of the verified code RAPTA-5. The code uses a set of high temperature physico-chemical properties of the fuel components as determined for commercially produced materials, fuel rod simulators and fuel rod bundles. The WWER fuel criteria available in Russia for design basis accidents do not generally differ from the similar criteria adopted for PWR`s. 12 figs., 11 refs.

  4. Central nervous system affecting drugs and road traffic accidents ...

    African Journals Online (AJOL)

    Central nervous system affecting drugs and road traffic accidents among commercial motorcyclists. ... including driving under the influence of drugs that affect the central nervous system (CNS). ... Keywords: Brain, influence, riders, substances ...

  5. Technical Basis - Spent Nuclear Fuels (SNF) Project Radiation and Contamination Trending Program

    International Nuclear Information System (INIS)

    ELGIN, J.C.

    2000-01-01

    This report documents the technical basis for the Spent Nuclear Fuel (SNF) Program radiation and contamination trending program. The program consists of standardized radiation and contamination surveys of the KE Basin, radiation surveys of the KW basin, radiation surveys of the Cold Vacuum Drying Facility (CVD), and radiation surveys of the Canister Storage Building (CSB) with the associated tracking. This report also discusses the remainder of radiological areas within the SNFP that do not have standardized trending programs and the basis for not having this program in those areas

  6. Progress in realization of the state policy in RW and SNF Management in the Russian Federation

    International Nuclear Information System (INIS)

    Borzunov, Andrey I.

    1999-01-01

    The basic infrastructure at the majority of the enterprises for management of radioactive waste (RW) and spent nuclear fuel (SNF) built in Russia in the 1960s and 1970s are now morally and technically obsolete and require reconstruction. As stated in this presentation, the most complicated problem is the shortage of financial resources, and International support is very important. The presentation is organised in sections discussing (1) the problem, (2) basic aspects of the State policy in this field, (3) the federal institutions in charge, (4) the principles upon which the State policy is grounded, (5) the main objectives of the RW and SNF management in Russia, (6) the federal programme: Radioactive wastes and spent nuclear materials management, their disposal and burial for the period 1996-2005, (7) plans for impending solution of the problems of the Northern and Pacific regions of Russia, (8) some top priority work of Minatom, (9) measures planned at the Russian power plants, (10) some basic results so far, (11) international co-operation

  7. Progress in realization of the state policy in RW and SNF Management in the Russian Federation

    Energy Technology Data Exchange (ETDEWEB)

    Borzunov, Andrey I

    1999-07-01

    The basic infrastructure at the majority of the enterprises for management of radioactive waste (RW) and spent nuclear fuel (SNF) built in Russia in the 1960s and 1970s are now morally and technically obsolete and require reconstruction. As stated in this presentation, the most complicatedproblem is the shortage of financial resources, and International support is very important. The presentation is organised in sections discussing (1) the problem, (2) basic aspects of the State policy in this field, (3) the federal institutions in charge, (4) the principles upon which the State policy is grounded, (5) the main objectives of the RW and SNF management in Russia, (6) the federal programme: Radioactive wastes and spent nuclear materials management, their disposal and burial for the period 1996-2005, (7) plans for impending solution of the problems of the Northern and Pacific regions of Russia, (8) some top priority work of Minatom, (9) measures planned at the Russian power plants, (10) some basic results so far, (11) international co-operation.

  8. Categorization of PWR accident sequences and guidelines for fault trees: seismic initiators

    International Nuclear Information System (INIS)

    Kimura, C.Y.

    1984-09-01

    This study developed a set of dominant accident sequences that could be applied generically to domestic commercial PWRs as a standardized basis for a probabilistic seismic risk assessment. This was accomplished by ranking the Zion 1 accident sequences. The pertinent PWR safety systems were compared on a plant-by-plant basis to determine the applicability of the dominant accident sequences of Zion 1 to other PWR plants. The functional event trees were developed to describe the system functions that must work or not work in order for a certain accident sequence to happen, one for pipe breaks and one for transients

  9. MELCOR DB Construction for the Severe Accident Analysis DB

    International Nuclear Information System (INIS)

    Song, Y. M.; Ahn, K. I.

    2011-01-01

    The Korea Atomic Energy Research Institute (KAERI) has been constructing a severe accident analysis database (DB) under a National Nuclear R and D Program. In particular, an MAAP (commercial code being widely used in industries for integrated severe accident analysis) DB for many scenarios including a station blackout (SBO) has been completed. This paper shows the MELCOR DB construction process with examples of SBO scenarios, and the results will be used for a comparison with the MAAP DB

  10. Empirical Risk Analysis of Severe Reactor Accidents in Nuclear Power Plants after Fukushima

    OpenAIRE

    Kaiser, Jan Christian

    2012-01-01

    Many countries are reexamining the risks connected with nuclear power generation after the Fukushima accidents. To provide updated information for the corresponding discussion a simple empirical approach is applied for risk quantification of severe reactor accidents with International Nuclear and Radiological Event Scale (INES) level ≥5. The analysis is based on worldwide data of commercial nuclear facilities. An empirical hazard of 21 (95% confidence intervals (CI) 4; 62) severe accidents am...

  11. Severe accident risks: An assessment for five US nuclear power plants

    International Nuclear Information System (INIS)

    1991-01-01

    This report summarizes an assessment of the risks from severe accidents in five commercial nuclear power plants in the United State. These risks are measured in a number of ways, including: the estimated frequencies of core damage accidents from internally initiated accidents and externally initiated accidents for two of the plants; the performance of containment structures under severe accident loadings; the potential magnitude of radionuclide releases and offsite consequences of such accidents; and the overall risk (the product of accident frequencies and consequences). Supporting this summary report are a large number of reports written under contract to NRC that provide the detailed discussion of the methods used and results obtained in these risk studies. This report, Volume 3, contains two appendices. Appendix D summarizes comments received, and staff responses, on the first (February 1987) draft of NUREG-1150. Appendix E provides a similar summary of comments and responses, but for the second (June 1989) version of the report

  12. Commercial truck parking and other safety issues.

    Science.gov (United States)

    2015-10-01

    Commercial truck parking is a safety issue, since trucks are involved in approximately 10% of all fatal accidents on interstates and : parkways in Kentucky. Drivers experience schedule demands and long hours on the road, yet they cannot easily determ...

  13. Accidents - Chernobyl accident

    International Nuclear Information System (INIS)

    2004-01-01

    This file is devoted to the Chernobyl accident. It is divided in four parts. The first part concerns the accident itself and its technical management. The second part is relative to the radiation doses and the different contaminations. The third part reports the sanitary effects, the determinists ones and the stochastic ones. The fourth and last part relates the consequences for the other European countries with the case of France. Through the different parts a point is tackled with the measures taken after the accident by the other countries to manage an accident, the cooperation between the different countries and the groups of research and studies about the reactors safety, and also with the international medical cooperation, specially for the children, everything in relation with the Chernobyl accident. (N.C.)

  14. Computational modeling of Repeat1 region of INI1/hSNF5: An evolutionary link with ubiquitin

    Science.gov (United States)

    Bhutoria, Savita

    2016-01-01

    Abstract The structure of a protein can be very informative of its function. However, determining protein structures experimentally can often be very challenging. Computational methods have been used successfully in modeling structures with sufficient accuracy. Here we have used computational tools to predict the structure of an evolutionarily conserved and functionally significant domain of Integrase interactor (INI)1/hSNF5 protein. INI1 is a component of the chromatin remodeling SWI/SNF complex, a tumor suppressor and is involved in many protein‐protein interactions. It belongs to SNF5 family of proteins that contain two conserved repeat (Rpt) domains. Rpt1 domain of INI1 binds to HIV‐1 Integrase, and acts as a dominant negative mutant to inhibit viral replication. Rpt1 domain also interacts with oncogene c‐MYC and modulates its transcriptional activity. We carried out an ab initio modeling of a segment of INI1 protein containing the Rpt1 domain. The structural model suggested the presence of a compact and well defined ββαα topology as core structure in the Rpt1 domain of INI1. This topology in Rpt1 was similar to PFU domain of Phospholipase A2 Activating Protein, PLAA. Interestingly, PFU domain shares similarity with Ubiquitin and has ubiquitin binding activity. Because of the structural similarity between Rpt1 domain of INI1 and PFU domain of PLAA, we propose that Rpt1 domain of INI1 may participate in ubiquitin recognition or binding with ubiquitin or ubiquitin related proteins. This modeling study may shed light on the mode of interactions of Rpt1 domain of INI1 and is likely to facilitate future functional studies of INI1. PMID:27261671

  15. Human Error and Commercial Aviation Accidents: A Comprehensive, Fine-Grained Analysis Using HFACS

    National Research Council Canada - National Science Library

    Shappell, Scott A; Detwiler, Cristy A; Holcomb, Kali A; Hackworth, Carla A; Boquet, Albert J; Wiegmann, Douglas A

    2006-01-01

    .... The aim of this study was to extend previous examinations of aviation accidents to include specific aircrew, environmental, supervisory, and organizational factors associated with 14 CFR Part 121...

  16. A novel Snf2 protein maintains trans-generational regulatory states established by paramutation in maize.

    Directory of Open Access Journals (Sweden)

    Christopher J Hale

    2007-10-01

    Full Text Available Paramutations represent heritable epigenetic alterations that cause departures from Mendelian inheritance. While the mechanism responsible is largely unknown, recent results in both mouse and maize suggest paramutations are correlated with RNA molecules capable of affecting changes in gene expression patterns. In maize, multiple required to maintain repression (rmr loci stabilize these paramutant states. Here we show rmr1 encodes a novel Snf2 protein that affects both small RNA accumulation and cytosine methylation of a proximal transposon fragment at the Pl1-Rhoades allele. However, these cytosine methylation differences do not define the various epigenetic states associated with paramutations. Pedigree analyses also show RMR1 does not mediate the allelic interactions that typically establish paramutations. Strikingly, our mutant analyses show that Pl1-Rhoades RNA transcript levels are altered independently of transcription rates, implicating a post-transcriptional level of RMR1 action. These results suggest the RNA component of maize paramutation maintains small heterochromatic-like domains that can affect, via the activity of a Snf2 protein, the stability of nascent transcripts from adjacent genes by way of a cotranscriptional repression process. These findings highlight a mechanism by which alleles of endogenous loci can acquire novel expression patterns that are meiotically transmissible.

  17. Inter-modal Transportation of Spent Nuclear Fuel from Office of Civilian Radioactive Waste Management Sites

    International Nuclear Information System (INIS)

    Schmid, St.; Thrower, A.; Best, R.E.

    2009-01-01

    U.S. Department of Energy (DOE) plans to ship most commercial spent nuclear fuel (SNF) by rail in sealed transportation, aging and disposal (TAD) canisters. Based on current and projected dry SNF storage programs, DOE believes the majority of commercial nuclear sites would have the capacity to load and prepare large-capacity, canister-based dry storage canisters such as the proposed TAD systems. Thus, only a small fraction of SNF, such as odd lots and SNF not meeting TAD criteria, is projected for truck (highway) shipment. However, at some commercial facilities rail tracks do not extend to the site, or on-site rail does not extend to the site's proposed loading spot, and inter-modal transfers will be required. Advance coordination between DOE and commercial site operators, commercial carriers, specialized carriers and riggers, and state, tribal and local routing officials will be necessary to establish inter-modal transfer areas and obtain necessary permits to move heavy loads over highways. Although inter-modal transfers can involve a number of steps and several different entities acting in close coordination, such moves are commonly performed by industry and the system requirements are well-understood. (authors)

  18. Cleanup and decommissioning of a nuclear reactor after a severe accident

    International Nuclear Information System (INIS)

    1992-01-01

    Although the development of commercial nuclear power plants has in general been associated with an excellent record of nuclear safety, the possibility of a severe accident resulting in major fuel and core damage cannot be excluded and such accidents have in fact already occurred. For over a decade, IAEA publications have provided technical guidance and recommendations for post-accident planning to be considered by appropriate authorities. Guidance and recommendations have recently been published on the management of damaged nuclear fuel, sealing of the reactor building and related safety and performance assessment aspects. The present technical report on the cleanup and decommissioning of reactors which have undergone a severe accident represents a further publication in the series. Refs, figs and tabs.

  19. Frequency of Specific Categories of Aviation Accidents and Incidents During 2001-2010

    Science.gov (United States)

    Evans, Joni K.

    2014-01-01

    The purpose of this study was to determine the types of accidents or incidents that are most important to the aviation safety risk. All accidents and incidents from 2001-2010 were assigned occurrence categories based on the taxonomy developed by the Commercial Aviation Safety Team/International Civil Aviation Organization (CAST/ICAO) Common Taxonomy Team (CICTT). The most frequently recorded categories were selected within each of five metrics: total accidents, fatal accidents, total injuries, fatal injuries and total incidents. This analysis was done separately for events within Part 121, Scheduled Part 135, Non-Scheduled Part 135 and Part 91. Combining those five sets of categories resulted in groups of between seven and eleven occurrence categories, depending on the flight operation. These groups represent 65-85% of all accidents and 68-81% of incidents.

  20. DESIGN VERIFICATION REPORT SPENT NUCLEAR FUEL (SNF) PROJECT CANISTER STORAGE BUILDING (CSB)

    International Nuclear Information System (INIS)

    BAZINET, G.D.

    2003-01-01

    The Sub-project W379, ''Spent Nuclear Fuel Canister Storage Building (CSB),'' was established as part of the Spent Nuclear Fuel (SNF) Project. The primary mission of the CSB is to safely store spent nuclear fuel removed from the K Basins in dry storage until such time that it can be transferred to the national geological repository at Yucca Mountain Nevada. This sub-project was initiated in late 1994 by a series of studies and conceptual designs. These studies determined that the partially constructed storage building, originally built as part of the Hanford Waste Vitrification Plant (HWVP) Project, could be redesigned to safely store the spent nuclear fuel. The scope of the CSB facility initially included a receiving station, a hot conditioning system, a storage vault, and a Multi-Canister Overpack (MCO) Handling Machine (MHM). Because of evolution of the project technical strategy, the hot conditioning system was deleted from the scope and MCO welding and sampling stations were added in its place. This report outlines the methods, procedures, and outputs developed by Project W379 to verify that the provided Structures, Systems, and Components (SSCs): satisfy the design requirements and acceptance criteria; perform their intended function; ensure that failure modes and hazards have been addressed in the design; and ensure that the SSCs as installed will not adversely impact other SSCs. The original version of this document was prepared by Vista Engineering for the SNF Project. Revision 1 documented verification actions that were pending at the time the initial report was prepared. Revision 3 of this document incorporates MCO Cover Cap Assembly welding verification activities. Verification activities for the installed and operational SSCs have been completed

  1. Commercial-grade motors in safety-related applications: Final report

    International Nuclear Information System (INIS)

    Holzman, P.M.

    1988-04-01

    The objective of this project was to discuss the process necessary to utilize commercial grade equipment in safety related applications and to provide utilities with guidance for accepting commercial grade motors for safety-related applications. The generic commercial-grade concepts presented in this report can be successfully applied to motors. Commercial grade item utilization has the greatest applicability to motors in ''mild'' environments, because these motors are essentially similar to commercial grade motors in materials, construction methods, and capabilities. The acceptance process is less applicable to motors that are subject to ''harsh'' environments during postulated accidents, because of the unique design features and testing required to qualify these motors

  2. Commercial nuclear power: Assuring safety for the future

    International Nuclear Information System (INIS)

    Ramsey, C.B.; Modarres, M.

    1998-03-01

    This timely book offers insights into the benefits of nuclear power as well as the technological and environmental challenges facing the nuclear industry. Containing the results of worldwide scientific studies and industrial site visits, the book represents a timely focus on the applications of commercial nuclear power, the potential benefits to be gained from contained nuclear use, the environmental risks of nuclear power, and the prevention of nuclear accidents.This timely book offers insights into the benefits of nuclear power as well as the technological and environmental challenges facing the nuclear industry. Containing the results of worldwide scientific studies and industrial site visits, the book represents a timely focus on the applications of commercial nuclear power, the potential benefits to be gained from contained nuclear use, the environmental risks of nuclear power, and the prevention of nuclear accidents

  3. Test analysis and research on static choice reaction ability of commercial vehicle drivers

    Science.gov (United States)

    Zhang, Lingchao; Wei, Lang; Qiao, Jie; Tian, Shun; Wang, Shengchang

    2017-03-01

    Drivers' choice reaction ability has a certain relation with safe driving. It has important significance to research its influence on traffic safety. Firstly, the paper uses a choice reaction detector developed by research group to detect drivers' choice reaction ability of commercial vehicles, and gets 2641 effective samples. Then by using mathematical statistics method, the paper founds that average reaction time from accident group has no difference with non-accident group, and then introduces a variance rate of reaction time as a new index to replace it. The result shows that the test index choice reaction errors and variance rate of reaction time have positive correlations with accidents. Finally, according to testing results of the detector, the paper formulates a detection threshold with four levels for helping transportation companies to assess commercial vehicles drivers.

  4. Spent Nuclear Fuel (SNF) Cold Vacuum Drying (CVD) Facility Operations Manual

    Energy Technology Data Exchange (ETDEWEB)

    IRWIN, J.J.

    1999-07-02

    This document provides the Operations Manual for the Cold Vacuum Drying Facility (CVDF). The Manual was developed in conjunction with HNF-553, Spent Nuclear Fuel Project Final Safety Analysis Report Annex B--Cold Vacuum Drying Facility. The HNF-SD-SNF-DRD-002, 1999, Cold Vacuum Drying Facility Design Requirements, Rev. 4, and the CVDF Final Design Report. The Operations Manual contains general descriptions of all the process, safety and facility systems in the CVDF, a general CVD operations sequence and references to the CVDF System Design Descriptions (SDDs). This manual has been developed for the SNFP Operations Organization and shall be updated, expanded, and revised in accordance with future design, construction and startup phases of the CVDF until the CVDF final ORR is approved.

  5. The SWI/SNF chromatin-remodeling factors BAF60a, b, and c in nutrient signaling and metabolic control

    Directory of Open Access Journals (Sweden)

    Ruo-Ran Wang

    2017-07-01

    Full Text Available ABSTRACT Metabolic syndrome has become a global epidemic that adversely affects human health. Both genetic and environmental factors contribute to the pathogenesis of metabolic disorders; however, the mechanisms that integrate these cues to regulate metabolic physiology and the development of metabolic disorders remain incompletely defined. Emerging evidence suggests that SWI/SNF chromatin-remodeling complexes are critical for directing metabolic reprogramming and adaptation in response to nutritional and other physiological signals. The ATP-dependent SWI/SNF chromatin-remodeling complexes comprise up to 11 subunits, among which the BAF60 subunit serves as a key link between the core complexes and specific transcriptional factors. The BAF60 subunit has three members, BAF60a, b, and c. The distinct tissue distribution patterns and regulatory mechanisms of BAF60 proteins confer each isoform with specialized functions in different metabolic cell types. In this review, we summarize the emerging roles and mechanisms of BAF60 proteins in the regulation of nutrient sensing and energy metabolism under physiological and disease conditions.

  6. Mitigative techniques and analysis of generic site conditions for ground-water contamination associated with severe accidents

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, J.M.; Oberlander, P.L.; Skaggs, R.L.

    1984-04-01

    The purpose of this study is to evaluate the feasibility of using ground-water contaminant mitigation techniques to control radionuclide migration following a severe commercial nuclear power reactor accident. The two types of severe commercial reactor accidents investigated are: (1) containment basemat penetration of core melt debris which slowly cools and leaches radionuclides to the subsurface environment, and (2) containment basemat penetration of sump water without full penetration of the core mass. Six generic hydrogeologic site classifications are developed from an evaluation of reported data pertaining to the hydrogeologic properties of all existing and proposed commercial reactor sites. One-dimensional radionuclide transport analyses are conducted on each of the individual reactor sites to determine the generic characteristics of a radionuclide discharge to an accessible environment. Ground-water contaminant mitigation techniques that may be suitable, depending on specific site and accident conditions, for severe power plant accidents are identified and evaluated. Feasible mitigative techniques and associated constraints on feasibility are determined for each of the six hydrogeologic site classifications. The first of three case studies is conducted on a site located on the Texas Gulf Coastal Plain. Mitigative strategies are evaluated for their impact on contaminant transport and results show that the techniques evaluated significantly increased ground-water travel times. 31 references, 118 figures, 62 tables.

  7. Mitigative techniques and analysis of generic site conditions for ground-water contamination associated with severe accidents

    International Nuclear Information System (INIS)

    Shafer, J.M.; Oberlander, P.L.; Skaggs, R.L.

    1984-04-01

    The purpose of this study is to evaluate the feasibility of using ground-water contaminant mitigation techniques to control radionuclide migration following a severe commercial nuclear power reactor accident. The two types of severe commercial reactor accidents investigated are: (1) containment basemat penetration of core melt debris which slowly cools and leaches radionuclides to the subsurface environment, and (2) containment basemat penetration of sump water without full penetration of the core mass. Six generic hydrogeologic site classifications are developed from an evaluation of reported data pertaining to the hydrogeologic properties of all existing and proposed commercial reactor sites. One-dimensional radionuclide transport analyses are conducted on each of the individual reactor sites to determine the generic characteristics of a radionuclide discharge to an accessible environment. Ground-water contaminant mitigation techniques that may be suitable, depending on specific site and accident conditions, for severe power plant accidents are identified and evaluated. Feasible mitigative techniques and associated constraints on feasibility are determined for each of the six hydrogeologic site classifications. The first of three case studies is conducted on a site located on the Texas Gulf Coastal Plain. Mitigative strategies are evaluated for their impact on contaminant transport and results show that the techniques evaluated significantly increased ground-water travel times. 31 references, 118 figures, 62 tables

  8. Demonstrating the Feasibility of Molten Aluminum for Destroying Polymeric Encapsulants in SNF-Bearing Metallographic Mounts. Final Technical Report

    International Nuclear Information System (INIS)

    Dan Stout; Scott Ploger

    2004-01-01

    DOE-owned spent nuclear fuel (SNF) rods have been cross sectioned and mounted for metallography throughout the history of nuclear reactors. Many hundreds of these ''met mounts'' have accumulated in storage across the DOE complex. However, because of potential hydrogen generation from radiolysis of the polymeric encapsulants, the met mounts are problematic for eventual disposal in a geologic repository

  9. Spent Nuclear Fuel project stage and store K basin SNF in canister storage building functions and requirements. Revision 1

    International Nuclear Information System (INIS)

    Womack, J.C.

    1995-01-01

    This document establishes the functions and requirements baseline for the implementation of the Canister Storage Building Subproject. The mission allocated to the Canister Storage Building Subproject is to provide safe, environmentally sound staging and storage of K Basin SNF until a decision on the final disposition is reached and implemented

  10. Storage and treatment of SNF of Alfa class nuclear submarines: current status and problems

    International Nuclear Information System (INIS)

    Ignatiev, Sviatoslav; Zabudko, Alexey; Pankratov, Dmitry; Somov, Ivan; Suvorov, Gennady

    2007-01-01

    Available in abstract form only. Full text of publication follows: The current status and main problems associated with storage, defueling and following treatment of spent nuclear fuel (SNF) of Nuclear Submarines (NS) with heavy liquid metal cooled reactors are considered. In the final analysis these solutions could be realized in the form of separate projects to be funded through national and bi- and multilateral funding in the framework of the international collaboration of the Russian Federation on complex utilization of NS and rehabilitation of contaminated objects allocated in the North-West region of Russia. (authors)

  11. Maintenance and Safety Practices of Escalator in Commercial Buildings

    Science.gov (United States)

    Afida Isnaini Janipha, Nurul; Nur Aina Syed Alwee, Sharifah; Ariff, Raihan Mohd; Ismail, Faridah

    2018-02-01

    The escalator is very crucial to transport a person from one place to another. Nevertheless, there are many cases recorded the accidents in relation to escalator. These may occur due to lack of maintenance which leads to systems breakdown, poor safety practices, wear and tear, users’ negligence and others. Thus, proper maintenance systems need to be improvised to prevent and reduce escalator accident in future. This research was aimed to determine the escalator maintenance activities and safety practices in a commercial building. Three case studies were selected within Selangor area. Semi-structured interviews were conducted for collecting data from these three case studies. To achieve the aim of this research, the study was carried out on the maintenance activities, safety practices and cost related to escalator maintenance. As one of the important means of access in building, it is very crucial to increase effectiveness of escalator particularly in commercial building. It is expected that readers will get clear information on the maintenance activities and safety practices of escalator in commercial building.

  12. DESIGN VERIFICATION REPORT SPENT NUCLEAR FUEL (SNF) PROJECT CANISTER STORAGE BUILDING (CSB)

    Energy Technology Data Exchange (ETDEWEB)

    BAZINET, G.D.

    2003-02-12

    The Sub-project W379, ''Spent Nuclear Fuel Canister Storage Building (CSB),'' was established as part of the Spent Nuclear Fuel (SNF) Project. The primary mission of the CSB is to safely store spent nuclear fuel removed from the K Basins in dry storage until such time that it can be transferred to the national geological repository at Yucca Mountain Nevada. This sub-project was initiated in late 1994 by a series of studies and conceptual designs. These studies determined that the partially constructed storage building, originally built as part of the Hanford Waste Vitrification Plant (HWVP) Project, could be redesigned to safely store the spent nuclear fuel. The scope of the CSB facility initially included a receiving station, a hot conditioning system, a storage vault, and a Multi-Canister Overpack (MCO) Handling Machine (MHM). Because of evolution of the project technical strategy, the hot conditioning system was deleted from the scope and MCO welding and sampling stations were added in its place. This report outlines the methods, procedures, and outputs developed by Project W379 to verify that the provided Structures, Systems, and Components (SSCs): satisfy the design requirements and acceptance criteria; perform their intended function; ensure that failure modes and hazards have been addressed in the design; and ensure that the SSCs as installed will not adversely impact other SSCs. The original version of this document was prepared by Vista Engineering for the SNF Project. Revision 1 documented verification actions that were pending at the time the initial report was prepared. Revision 3 of this document incorporates MCO Cover Cap Assembly welding verification activities. Verification activities for the installed and operational SSCs have been completed.

  13. Accident management for severe accidents

    International Nuclear Information System (INIS)

    Bari, R.A.; Pratt, W.T.; Lehner, J.; Leonard, M.; Disalvo, R.; Sheron, B.

    1988-01-01

    The management of severe accidents in light water reactors is receiving much attention in several countries. The reduction of risk by measures and/or actions that would affect the behavior of a severe accident is discussed. The research program that is being conducted by the US Nuclear Regulatory Commission focuses on both in-vessel accident management and containment and release accident management. The key issues and approaches taken in this program are summarized. 6 refs

  14. Integrated data base report - 1996: US spent nuclear fuel and radioactive waste inventories, projections, and characteristics

    International Nuclear Information System (INIS)

    1997-12-01

    The Integrated Data Base Program has compiled historic data on inventories and characteristics of both commercial and U.S. Department of Energy (DOE) spent nuclear fuel (SNF) and commercial and U.S. government-owned radioactive wastes. Inventories of most of these materials are reported as of the end of fiscal year (FY) 1996, which is September 30, 1996. Commercial SNF and commercial uranium mill tailings inventories are reported on an end-of-calendar year (CY) basis. All SNF and radioactive waste data reported are based on the most reliable information available from government sources, the open literature, technical reports, and direct contacts. The information forecasted is consistent with the latest DOE/Energy Information Administration (EIA) projections of U.S. commercial nuclear power growth and the expected DOE-related and private industrial and institutional activities. The radioactive materials considered, on a chapter-by-chapter basis, are SNF, high-level waste, transuranic waste, low-level waste, uranium mill tailings, DOE Environmental Restoration Program contaminated environmental media, naturally occurring and accelerator-produced radioactive material, and mixed (hazardous and radioactive) low-level waste. For most of these categories, current and projected inventories are given through FY 2030, and the radioactivity and thermal power are calculated based on reported or estimated isotopic compositions

  15. Accident tolerant fuel cladding development: Promise, status, and challenges

    Science.gov (United States)

    Terrani, Kurt A.

    2018-04-01

    The motivation for transitioning away from zirconium-based fuel cladding in light water reactors to significantly more oxidation-resistant materials, thereby enhancing safety margins during severe accidents, is laid out. A review of the development status for three accident tolerant fuel cladding technologies, namely coated zirconium-based cladding, ferritic alumina-forming alloy cladding, and silicon carbide fiber-reinforced silicon carbide matrix composite cladding, is offered. Technical challenges and data gaps for each of these cladding technologies are highlighted. Full development towards commercial deployment of these technologies is identified as a high priority for the nuclear industry.

  16. Third party liability of nuclear installation decommissioning with Russian nuclear submarines as an example: insurance versus technologies

    International Nuclear Information System (INIS)

    Gavrilov, S.D.; Derevyankin, A.A.; Khamyanov, L.P.; Kovalenko, V.N.; Kovalivich, O.M.; Smirnov, P.L.

    2001-01-01

    Third party and environment of civil liability damage caused by incidents at military nuclear installations, for instance at decommissioned NPS (nuclear powered submarines), may be divided into three main trends: -) Liability of NPS without high-enriched irradiated nuclear fuel (SNF) for its self-submersion (radiation incident); -) Liability of NPS with SNF aboard for its self-submersion (radiation incident); and -) Liability of floating NPS for its SNF discharge (nuclear accident). Without step-by-step transition from the Russian Federation guaranties to insurance and making allowance for liability limits according to the Vienna Convention approach, the sizes of the financial guarantee for the civil liability of the NPS owner (Russian state), in US dollars of 2000, are approximately assessed as the following: -) storing decommissioned NPS or a floating module without SNF - from 12 to 25 thousand dollars per year (per one submarine or module); -) storing decommissioned NPS with SNF inside reactors cores - from 25 to 40 thousand dollars per year; -) assembly-by-assembly removing SNF from reactors' core of decommissioned NPS - up to 1.5 million dollars for undamaged reactor per the discharging period; -) SNF removing within reactor using the filled in-space reactor's core by liquid-phased hardened or dispersed solid-phase materials from decommissioned NPS - from 30 to 50 thousand dollars for undamaged reactor per the discharging period. Both rates and sums for NPS with damaged reactors are to be estimated for the each damaged reactor and NPS at all. It is necessary to perform the measures reducing the risk of nuclear accidents of NPS with undamaged SNF and NPS with damaged reactors in possibly short time. It will allow not only to cut risks by ten times and more, but also to accumulate necessary insurance reserves faster. These measures can be partially or completely executed using the preventing measures reserves assigned to all decommissioned Russian NPS and

  17. Third party liability of nuclear installation decommissioning with Russian nuclear submarines as an example: insurance versus technologies

    Energy Technology Data Exchange (ETDEWEB)

    Gavrilov, S.D. [PREKSAT Ltd., Moscow (Russian Federation); Derevyankin, A.A. [Reseaarch and Development Institute of Nuclear Power Engineering, Moscow (Russian Federation); Khamyanov, L.P. [All-Russian Research Institute on NPP Operation, Moscow (Russian Federation); Kovalenko, V.N. [Ministry for Nuclear Energy Of Russian, Moscow (Russian Federation); Kovalivich, O.M. [Research and Technological Center for Nuclear and Radiation Safety of Supervisory, Nuclear Energy State Commitee of Russia, Moscow (Russian Federation); Smirnov, P.L. [Nuclear Safety Institute of Russian Academy of Sciences, Moscow (Russian Federation)

    2001-07-01

    Third party and environment of civil liability damage caused by incidents at military nuclear installations, for instance at decommissioned NPS (nuclear powered submarines), may be divided into three main trends: -) Liability of NPS without high-enriched irradiated nuclear fuel (SNF) for its self-submersion (radiation incident); -) Liability of NPS with SNF aboard for its self-submersion (radiation incident); and -) Liability of floating NPS for its SNF discharge (nuclear accident). Without step-by-step transition from the Russian Federation guaranties to insurance and making allowance for liability limits according to the Vienna Convention approach, the sizes of the financial guarantee for the civil liability of the NPS owner (Russian state), in US dollars of 2000, are approximately assessed as the following: -) storing decommissioned NPS or a floating module without SNF - from 12 to 25 thousand dollars per year (per one submarine or module); -) storing decommissioned NPS with SNF inside reactors cores - from 25 to 40 thousand dollars per year; -) assembly-by-assembly removing SNF from reactors' core of decommissioned NPS - up to 1.5 million dollars for undamaged reactor per the discharging period; -) SNF removing within reactor using the filled in-space reactor's core by liquid-phased hardened or dispersed solid-phase materials from decommissioned NPS - from 30 to 50 thousand dollars for undamaged reactor per the discharging period. Both rates and sums for NPS with damaged reactors are to be estimated for the each damaged reactor and NPS at all. It is necessary to perform the measures reducing the risk of nuclear accidents of NPS with undamaged SNF and NPS with damaged reactors in possibly short time. It will allow not only to cut risks by ten times and more, but also to accumulate necessary insurance reserves faster. These measures can be partially or completely executed using the preventing measures reserves assigned to all decommissioned Russian NPS

  18. Phased Development of Accident Tolerant Fue

    Energy Technology Data Exchange (ETDEWEB)

    Bragg-Sitton, Shannon M.; Carmack, W. Jon

    2016-09-01

    The United States Department of Energy (U.S. DOE) Advanced Fuels Campaign (AFC) has adopted a three-phase approach for the development and eventual commercialization of enhanced, accident tolerant fuel (ATF) for light water reactors (LWRs). Extending from 2012 to 2016, AFC is currently coming to the end of Phase 1 research that has entailed Feasibility Assessment and Prioritization for a large number of proposed fuel systems (fuel and cladding) that could provide improved performance under accident conditions. Phase 1 activities will culminate with a prioritization of concepts for both near-term and long-term development based on the available experimental data and modeling predictions. This process will provide guidance to DOE on what concepts should be prioritized for investment in Phase 2 Development/Qualification activities based on technical performance improvements and probability of meeting the aggressive schedule to insert a lead fuel rod (LFR) in a commercial power reactor by 2022. While Phase 1 activities include small-scale fabrication work, materials characterization, and limited irradiation of samples, Phase 2 will require development teams to expand to industrial fabrication methods, conduct irradiation tests under more prototypic reactor conditions (i.e. in contact with reactor primary coolant at LWR conditions and in-pile transient testing), conduct additional characterization and post-irradiation examination, and develop a fuel performance code for the candidate ATF. Phase 2 will culminate in the insertion of an LFR (or lead fuel assembly) in a commercial power reactor. The Phase 3 Commercialization work will extend past 2022. Following post-irradiation examination of LFRs, partial-core reloads will be demonstrated. The commercialization phase will further entail the establishment of commercial fabrication capabilities and the transition of LWR cores to the new fuel. The three development phases described roughly correspond to the technology

  19. Assessment results of the South Korea TRIGA SNF to be shipped to INEEL

    International Nuclear Information System (INIS)

    Cole, Charles M.; Dirk, Willam J.; Cottam, Russel E.; Paik, Sam T.

    1997-01-01

    This paper describes the Training, Research, Isotope, General Atomics (TRIGA) spent nuclear fuel (SNF) examination at the Seoul and the Taejon Research Reactor Facilities in South Korea. The examination was required before the SNF would be accepted for transportation and storage at the INEEL. The results of the aluminum and stainless steel clad TRIGA fuel examination have been summarized. A description of the examination team training, the examination work plan and examination equipment is also included. This paper also explains the technical basis for the examination and physical condition criteria used to determine what, if any, additional packaging (canning) would be required for transportation and for the receipt and storage of the fuel at the INEEL. This paper delineates the preparation activities prior to the fuel examinations and includes (1) collecting spent fuel data; (2) preparatory work by the Korean Atomic Energy Research Institute (KAERI) for fuel examination: (3) preparation of a radionuclide report, 'Radionuclide Mass Inventory, Activity, Decay Heat, and Dose Rate Parametric Data for TRIGA Spent Nuclear Fuels' needed to provide input data for transportation and fuel acceptance at the Idaho National Engineering and Environmental Laboratory (INEEL); (4) gathering FRR Facility data; (5) preparation of Appendix A; (6) and coordination between the INEEL and KAERI. Included, are the unanticipated conditions encountered in the unloading of fuel from the dry storage casks in Taejon in preparation for examination, a description of the damaged condition of the fuel removed from the casks, and the apparent cause of the damages. Lessons learned from all the activities are also addressed. A brief description of the preparatory work for the shipment of the spent fuel from Korea to INEEL is included. (author)

  20. Assessment results of the South Korea TRIGA SNF to be shipped to INEEL

    International Nuclear Information System (INIS)

    Cole, C.M.; Dirk, W.J.; Cottam, R.E.; Paik, S.T.

    1997-01-01

    This paper describes the Training, Research, Isotope, General Atomics (TRIGA) spent nuclear fuel (SNF) examination at the Seoul and the Taejon Research Reactor Facilities in South Korea. The examination was required before the SNF would be accepted for transportation and storage at the INEEL. The results of the aluminum and stainless steel clad TRIGA fuel examination have been summarized. A description of the examination team training, the examination work plan and examination equipment is also included. This paper also explains the technical basis for the examination and physical condition criteria used to determine what, if any, additional packaging would be required for transportation and for the receipt and storage of the fuel at the INEEL. This paper delineates the preparation activities prior to the fuel examinations and includes (1) collecting spent fuel data; (2) preparatory work by the Korean Atomic Energy Research Institute (KAERI) for fuel examination: (3) preparation of a radionuclide report, Radionuclide Mass Inventory, Activity, Decay Heat, and Dose Rate Parametric Data for TRIGA Spent Nuclear Fuels needed to provide input data for transportation and fuel acceptance at the Idaho National Engineering and Environmental Laboratory (INEEL); (4) gathering FRR Facility data; and (5) coordination between the INEEL and KAERI. Included, are the unanticipated conditions encountered in the unloading of fuel from the dry storage casks in Taejon in preparation for examination, a description of the damaged condition of the fuel removed from the casks, and the apparent cause of the damages. Lessons learned from all the activities are also addressed. A brief description of the preparatory work for the shipment of the spent fuel from Korea to INEEL is included

  1. DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells

    Directory of Open Access Journals (Sweden)

    Adone Mohd-Sarip

    2017-07-01

    Full Text Available The Nucleosome Remodeling and Deacetylase (NURD complex is a key regulator of cell differentiation that has also been implicated in tumorigenesis. Loss of the NURD subunit Deleted in Oral Cancer 1 (DOC1 is associated with human oral squamous cell carcinomas (OSCCs. Here, we show that restoration of DOC1 expression in OSCC cells leads to a reversal of epithelial-mesenchymal transition (EMT. This is caused by the DOC1-dependent targeting of NURD to repress key transcriptional regulators of EMT. NURD recruitment drives extensive epigenetic reprogramming, including eviction of the SWI/SNF remodeler, formation of inaccessible chromatin, H3K27 deacetylation, and binding of PRC2 and KDM1A, followed by H3K27 methylation and H3K4 demethylation. Strikingly, depletion of SWI/SNF mimics the effects of DOC1 re-expression. Our results suggest that SWI/SNF and NURD function antagonistically to control chromatin state and transcription. We propose that disturbance of this dynamic equilibrium may lead to defects in gene expression that promote oncogenesis.

  2. Evaluation of severe accident risks, Grand Gulf, Unit 1: Appendices

    International Nuclear Information System (INIS)

    Brown, T.D.; Breeding, R.J.; Jow, H.N.; Higgins, S.J.; Shiver, A.W.; Helton, J.C.; Amos, C.N.

    1990-12-01

    In support of the Nuclear Regulatory Commission's (NRC's) assessment of the risk from severe accidents at commercial nuclear power plants in the US report in NUREG-1150, the Severe Accident Risk Reduction Program (SARRP) has completed a revised calculation of the risk to the general public from severe accidents at the Grand Gulf Nuclear Station, Unit 1. This power plant, located in Port Gibson, Mississippi, is operated by the System Energy Resources, Inc. (SERI). The emphasis in this risk analysis was not on determining a ''so-called'' point estimate of risk. Rather, it was to determine the distribution of risk, and to discover the uncertainties that account for the breadth of this distribution. Off-site risk initiated by events internal to the power plant was assessed. This document provides Appendices A through E for this report. Topics included are, respectively: supporting information for the accident progression analysis; supporting information for the source term analysis; supporting information for the consequence analysis; risk results; and sampling information

  3. Multi-purpose canister storage unit and transfer cask thermal analysis

    International Nuclear Information System (INIS)

    Montgomery, R.A.; Niemer, K.A.; Lindner, C.N.

    1997-01-01

    Spent Nuclear Fuel (SNF) generated at commercial nuclear power plants throughout the US is a concern because of continued delays in obtaining a safe, permanent disposal facility. Most utilities maintain their SNF in wet storage pools; however, after decades of use, many pools are filled to capacity. Unfortunately, DOE's proposed final repository at Yucca Mountain is at least 10 years from completion, and commercial power utilities have few options for SNF storage in the interim. The Multi-Purpose Canister (MPC) system, sponsored by DOE's Office of Civilian Radioactive Waste Management, is a viable solution to the interim storage problem. The system is designed for interim dry storage, transport, and ultimate disposal of commercial SNF. The MPC system consists of four separate components: an MPC, Transfer Cask, Storage Unit, and Transport Cask. The SNF assemblies are loaded and sealed inside the helium-filled steel MPC. Once sealed, the MPC is not reopened, eliminating the need to re-handle the individual spent fuel assemblies. The MPC is transferred, using the MPC Transfer Cask, into a cylindrical, reinforced-concrete Storage Unit for on-site dry storage. The MPC may be removed from the Storage Unit at any time and transferred into the MPC Transport Cask for transport to the final repository. This paper discusses the analytical approach used to evaluate the heat transfer characteristics of an MPC containing SNF assemblies in the MPC Transfer Cask and Storage Unit

  4. Commercialization of the global nuclear energy partnership (GNEP)

    International Nuclear Information System (INIS)

    Loewen Eric P.; Boaz, Jeffery; Saito, Earl; Boardman, Chuck

    2007-01-01

    In February 2006 President Bush announced the Advanced Energy Initiative, which included the Department of Energy's (DOE) Global Nuclear Energy Partnership (GNEP). GNEP has seven broad goals, one of the major elements being to develop and deploy advanced nuclear fuel recycling technology. DOE is contemplating accelerating the deployment of these technologies to achieve the construction of a commercial scale application of these technologies. DOE now defines this approach as 'two simultaneous tracks: (1) deployment of commercial scale facilities for which advanced technologies are available now or in the near future, and (2) further research and development of transmutation fuels technologies'. GE believes an integrated technical solution, using existing reactor and fuel reprocessing technologies, is achievable in the near term to accelerate the commercial demonstration of GNEP infrastructure. The concept involves a single, integrated, commercial scale, recycling facility consisting of the Consolidated Fuel Treatment Center (CFTC), capable of processing LWR and fast reactor Spent Nuclear Fuel (SNF) and fabricating Advanced Recycling Reactor (ARR) actinide fuel. The integrated facility would include a fast reactor that uses actinide-bearing fuel to produce electricity. For optimal performance, GE believes this integrated facility should be co-located to eliminate transportation between the CFTC and ARR, and enhance proliferation resistance. This Advanced Recycling Center takes advantage of previous investments by government and industry in fast reactor technology research and development. To allow for commercial acceptance, a prototypical demonstration reactor and associated fuel cycle facility will be constructed, tested, and licensed. Taking advantage of GE's NRC-reviewed modular sodium-cooled PRISM reactor, only a single reactor will be needed and the cost and risk minimized in the initial phase of the program. This paper outlines a process and a schedule to

  5. Characterizing the Severe Turbulence Environments Associated With Commercial Aviation Accidents. Part 1; 44 Case Study Synoptic Observational Analyses

    Science.gov (United States)

    Kaplan, Michael L.; Huffman, Allan W.; Lux, Kevin M.; Charney, Joseph J.; Riordan, Allan J.; Lin, Yuh-Lang; Proctor, Fred H. (Technical Monitor)

    2002-01-01

    A 44 case study analysis of the large-scale atmospheric structure associated with development of accident-producing aircraft turbulence is described. Categorization is a function of the accident location, altitude, time of year, time of day, and the turbulence category, which classifies disturbances. National Centers for Environmental Prediction Reanalyses data sets and satellite imagery are employed to diagnose synoptic scale predictor fields associated with the large-scale environment preceding severe turbulence. These analyses indicate a predominance of severe accident-producing turbulence within the entrance region of a jet stream at the synoptic scale. Typically, a flow curvature region is just upstream within the jet entrance region, convection is within 100 km of the accident, vertical motion is upward, absolute vorticity is low, vertical wind shear is increasing, and horizontal cold advection is substantial. The most consistent predictor is upstream flow curvature and nearby convection is the second most frequent predictor.

  6. Defense High Level Waste Disposal Container System Description Document

    International Nuclear Information System (INIS)

    Pettit, N. E.

    2001-01-01

    The Defense High Level Waste Disposal Container System supports the confinement and isolation of waste within the Engineered Barrier System of the Monitored Geologic Repository (MGR). Disposal containers are loaded and sealed in the surface waste handling facilities, transferred to the underground through the accesses using a rail mounted transporter, and emplaced in emplacement drifts. The defense high level waste (HLW) disposal container provides long-term confinement of the commercial HLW and defense HLW (including immobilized plutonium waste forms [IPWF]) placed within disposable canisters, and withstands the loading, transfer, emplacement, and retrieval loads and environments. US Department of Energy (DOE)-owned spent nuclear fuel (SNF) in disposable canisters may also be placed in a defense HLW disposal container along with commercial HLW waste forms, which is known as co-disposal. The Defense High Level Waste Disposal Container System provides containment of waste for a designated period of time, and limits radionuclide release. The disposal container/waste package maintains the waste in a designated configuration, withstands maximum handling and rockfall loads, limits the individual canister temperatures after emplacement, resists corrosion in the expected handling and repository environments, and provides containment of waste in the event of an accident. Defense HLW disposal containers for HLW disposal will hold up to five HLW canisters. Defense HLW disposal containers for co-disposal will hold up to five HLW canisters arranged in a ring and one DOE SNF canister inserted in the center and/or one or more DOE SNF canisters displacing a HLW canister in the ring. Defense HLW disposal containers also will hold two Multi-Canister Overpacks (MCOs) and two HLW canisters in one disposal container. The disposal container will include outer and inner cylinders, outer and inner cylinder lids, and may include a canister guide. An exterior label will provide a means by

  7. Another 60Co hot cell accident

    International Nuclear Information System (INIS)

    Steidley, K.D.; Zeik, G.S.; Ouellette, R.

    1979-01-01

    An accident at a commercial irradiation facility is described. Because of inadequate safety arrangements a worker entered the irradiation cell while the 500,000 Ci 60 Co source was exposed. The duration of the exposure was established by re-enactment of the worker's movements, and dose rates at various locations at the accident site were measured. From the results a total absorbed dose of 210 rad to the surface of the victim was calculated. This and results of chromosomal aberration studies (200 rad) and the worker's film badge reading (126 rad) lead to the assignment of a nominal 200 rad absorbed dose. The worker was taken to two local hospital emergency departments, both of which examined and discharged him. Eventually he was admitted to a medical centre with experience of radiation effects. His symptoms and treatment during his 7 week stay in hospital are described and his blood counts vs time are shown graphically. As a result of the unsatisfactory response of the emergency departments the NRC has modified its licensing procedures to include specific arrangements with a local hospital. It is stressed that accident dosage estimates should always be supplied to the patient or his personal physician. (author)

  8. Generic implications of the Chernobyl accident

    International Nuclear Information System (INIS)

    Sege, G.

    1989-01-01

    The US Nuclear Regulatory Commission (NRC) staff's assessment of the generic implications of the Chernobyl accident led to the conclusion that no immediate changes in the NRC's regulations regarding design or operation of US commercial reactors are needed. However, further consideration of certain issues was recommended. This paper discusses those issues and the studies being addressed to them. Although 24 tasks relating to light water reactor issues are identified in the Chernobyl follow-up research program, only four are new initiatives originating from Chernobyl implications. The remainder are limited modifications of ongoing programs designed to ensure that those programs duly reflect any lessons that may be drawn from the Chernobyl experience. The four new study tasks discussed include a study of reactivity transients, to reconfirm or bring into question the adequacy of potential reactivity accident sequences hitherto selected as a basis for design approvals; analysis of risk at low power and shutdown; a study of procedure violations; and a review of current NRC testing requirements for balance of benefits and risks. Also discussed, briefly, are adjustments to ongoing studies in the areas of operational controls, design, containment, emergency planning, and severe accident phenomena

  9. Spent Nuclear Fuel (SNF) Cold Vacuum Drying (CVD) Facility Operations Manual; FINAL

    International Nuclear Information System (INIS)

    IRWIN, J.J.

    1999-01-01

    This document provides the Operations Manual for the Cold Vacuum Drying Facility (CVDF). The Manual was developed in conjunction with HNF-553, Spent Nuclear Fuel Project Final Safety Analysis Report Annex B-Cold Vacuum Drying Facility. The HNF-SD-SNF-DRD-002, 1999, Cold Vacuum Drying Facility Design Requirements, Rev. 4, and the CVDF Final Design Report. The Operations Manual contains general descriptions of all the process, safety and facility systems in the CVDF, a general CVD operations sequence and references to the CVDF System Design Descriptions (SDDs). This manual has been developed for the SNFP Operations Organization and shall be updated, expanded, and revised in accordance with future design, construction and startup phases of the CVDF until the CVDF final ORR is approved

  10. Status of US program for disposal of spent nuclear fuel

    International Nuclear Information System (INIS)

    Smith, R.I.

    1991-04-01

    In this paper, a brief history of the United States' program for the disposal of spent nuclear fuel (SNF) and the legislative acts that have guided the program are discussed. The current plans and schedules for beginning acceptance of SNF from the nuclear utilities for disposal are described, and some of the development activities supporting the program are discussed. And finally, the viability of the SNF disposal fee presently paid into the Nuclear Waste Fund by the owners/generators of commercial SNF and high-level waste (HLW) is examined. 12 refs., 9 figs

  11. Postulated accidents

    International Nuclear Information System (INIS)

    Ullrich, W.

    1980-01-01

    This lecture on 'Postulated Accidents' is the first of a series of lectures on the dynamic and transient behaviour of nuclear power plants, especially pressurized water reactors. The main points covered will be: Reactivity Accidents, Transients (Intact Loop) and Loss of Cooland Accidents (LOCA) including small leak. This lecture will discuss the accident analysis in general, the definition of the various operational phases, the accident classification, and, as an example, an accident sequence analysis on the basis of 'Postulated Accidents'. (orig./RW)

  12. Severe accident risks: An assessment for five US nuclear power plants: Appendices A, B, and C

    International Nuclear Information System (INIS)

    1990-12-01

    This report summarizes an assessment of the risks from severe accidents in five commercial nuclear power plants in the United States. These risks are measured in a number of ways, including: the estimated frequencies of core damage accidents from internally initiated accidents and externally initiated accidents for two or the plants; the performance of containment structures under severe accident loadings; the potential magnitude of radionuclide release and offsite consequences of such accidents; and the overall risk (the product of accident frequencies and consequences). Supporting this summary report are a large number of reports written under contract to NRC that provide the detailed discussion of the methods used and results obtained in these risk studies. Volume 2 of this report contains three appendices, providing greater detail on the methods used, an example risk calculation, and more detailed discussion of particular technical issues found important in the risk studies

  13. The impact of motorcycle accidents on the obstetric population in ...

    African Journals Online (AJOL)

    Contexts: Motorcycle accidents are very common in most cities in Nigeria since the introduction of motorcycle for public commercial transportation in the early 1980s and because most pregnant women use this popular means of transport it may contribute to non-obstetric causes of maternal and perinatal morbidity and ...

  14. Accident management

    International Nuclear Information System (INIS)

    Lutz, R.J.; Monty, B.S.; Liparulo, N.J.; Desaedeleer, G.

    1989-01-01

    The foundation of the framework for a Severe Accident Management Program is the contained in the Probabilistic Safety Study (PSS) or the Individual Plant Evaluations (IPE) for a specific plant. The development of a Severe Accident Management Program at a plant is based on the use of the information, in conjunction with other applicable information. A Severe Accident Management Program must address both accident prevention and accident mitigation. The overall Severe Accident Management framework must address these two facets, as a living program in terms of gathering the evaluating information, the readiness to respond to an event. Significant international experience in the development of severe accident management programs exist which should provide some direction for the development of Severe Accident Management in the U.S. This paper reports that the two most important elements of a Severe Accident Management Program are the Emergency Consultation process and the standards for measuring the effectiveness of individual Severe Accident Management Programs at utilities

  15. Design Verification Report Spent Nuclear Fuel (SNF) Project Canister Storage Building (CSB)

    Energy Technology Data Exchange (ETDEWEB)

    BAZINET, G.D.

    2001-05-15

    The Sub-project W379, ''Spent Nuclear Fuel Canister Storage Building (CSB),'' was established as part of the Spent Nuclear Fuel (SNF) Project. The primary mission of the CSB is to safely store spent nuclear fuel removed from the K Basins in dry storage until such time that it can be transferred to the national geological repository at Yucca Mountain Nevada. This sub-project was initiated in late 1994 by a series of studies and conceptual designs. These studies determined that the partially constructed storage building, originally built as part of the Hanford Waste Vitrification Plant (HWVP) Project, could be redesigned to safely store the spent nuclear fuel. The scope of the CSB facility initially included a receiving station, a hot conditioning system, a storage vault, and a Multi-Canister Overpack (MCO) Handling Machine (MHM). Because of evolution of the project technical strategy, the hot conditioning system was deleted from the scope and MCO welding and sampling stations were added in its place. This report outlines the methods, procedures, and outputs developed by Project W379 to verify that the provided Structures, Systems, and Components (SSCs): satisfy the design requirements and acceptance criteria; perform their intended function; ensure that failure modes and hazards have been addressed in the design; and ensure that the SSCs as installed will not adversely impact other SSCs. The original version of this document was prepared by Vista Engineering for the SNF Project. Revision 1 documented verification actions that were pending at the time the initial report was prepared. Verification activities for the installed and operational SSCs have been completed. Verification of future additions to the CSB related to the canister cover cap and welding fixture system and MCO Internal Gas Sampling equipment will be completed as appropriate for those components. The open items related to verification of those requirements are noted in section 3

  16. Design Verification Report Spent Nuclear Fuel (SNF) Project Canister Storage Building (CSB)

    Energy Technology Data Exchange (ETDEWEB)

    BAZINET, G.D.

    2000-11-03

    The Sub-project W379, ''Spent Nuclear Fuel Canister Storage Building (CSB),'' was established as part of the Spent Nuclear Fuel (SNF) Project. The primary mission of the CSB is to safely store spent nuclear fuel removed from the K Basins in dry storage until such time that it can be transferred to the national geological repository at Yucca Mountain Nevada. This sub-project was initiated in late 1994 by a series of studies and conceptual designs. These studies determined that the partially constructed storage building, originally built as part of the Hanford Waste Vitrification Plant (HWVP) Project, could be redesigned to safely store the spent nuclear fuel. The scope of the CSB facility initially included a receiving station, a hot conditioning system, a storage vault, and a Multi-Canister Overpack (MCO) Handling Machine (MHM). Because of evolution of the project technical strategy, the hot conditioning system was deleted from the scope and MCO welding and sampling stations were added in its place. This report outlines the methods, procedures, and outputs developed by Project W379 to verify that the provided Structures, Systems, and Components (SSCs): satisfy the design requirements and acceptance criteria; perform their intended function; ensure that failure modes and hazards have been addressed in the design; and ensure that the SSCs as installed will not adversely impact other SSCs. The original version of this document was prepared by Vista Engineering for the SNF Project. The purpose of this revision is to document completion of verification actions that were pending at the time the initial report was prepared. Verification activities for the installed and operational SSCs have been completed. Verification of future additions to the CSB related to the canister cover cap and welding fixture system and MCO Internal Gas Sampling equipment will be completed as appropriate for those components. The open items related to verification of those

  17. Design Verification Report Spent Nuclear Fuel (SNF) Project Canister Storage Building (CSB)

    International Nuclear Information System (INIS)

    BAZINET, G.D.

    2001-01-01

    The Sub-project W379, ''Spent Nuclear Fuel Canister Storage Building (CSB),'' was established as part of the Spent Nuclear Fuel (SNF) Project. The primary mission of the CSB is to safely store spent nuclear fuel removed from the K Basins in dry storage until such time that it can be transferred to the national geological repository at Yucca Mountain Nevada. This sub-project was initiated in late 1994 by a series of studies and conceptual designs. These studies determined that the partially constructed storage building, originally built as part of the Hanford Waste Vitrification Plant (HWVP) Project, could be redesigned to safely store the spent nuclear fuel. The scope of the CSB facility initially included a receiving station, a hot conditioning system, a storage vault, and a Multi-Canister Overpack (MCO) Handling Machine (MHM). Because of evolution of the project technical strategy, the hot conditioning system was deleted from the scope and MCO welding and sampling stations were added in its place. This report outlines the methods, procedures, and outputs developed by Project W379 to verify that the provided Structures, Systems, and Components (SSCs): satisfy the design requirements and acceptance criteria; perform their intended function; ensure that failure modes and hazards have been addressed in the design; and ensure that the SSCs as installed will not adversely impact other SSCs. The original version of this document was prepared by Vista Engineering for the SNF Project. Revision 1 documented verification actions that were pending at the time the initial report was prepared. Verification activities for the installed and operational SSCs have been completed. Verification of future additions to the CSB related to the canister cover cap and welding fixture system and MCO Internal Gas Sampling equipment will be completed as appropriate for those components. The open items related to verification of those requirements are noted in section 3.1.5 and will be

  18. Design Verification Report Spent Nuclear Fuel (SNF) Project Canister Storage Building (CSB)

    International Nuclear Information System (INIS)

    BAZINET, G.D.

    2000-01-01

    The Sub-project W379, ''Spent Nuclear Fuel Canister Storage Building (CSB),'' was established as part of the Spent Nuclear Fuel (SNF) Project. The primary mission of the CSB is to safely store spent nuclear fuel removed from the K Basins in dry storage until such time that it can be transferred to the national geological repository at Yucca Mountain Nevada. This sub-project was initiated in late 1994 by a series of studies and conceptual designs. These studies determined that the partially constructed storage building, originally built as part of the Hanford Waste Vitrification Plant (HWVP) Project, could be redesigned to safely store the spent nuclear fuel. The scope of the CSB facility initially included a receiving station, a hot conditioning system, a storage vault, and a Multi-Canister Overpack (MCO) Handling Machine (MHM). Because of evolution of the project technical strategy, the hot conditioning system was deleted from the scope and MCO welding and sampling stations were added in its place. This report outlines the methods, procedures, and outputs developed by Project W379 to verify that the provided Structures, Systems, and Components (SSCs): satisfy the design requirements and acceptance criteria; perform their intended function; ensure that failure modes and hazards have been addressed in the design; and ensure that the SSCs as installed will not adversely impact other SSCs. The original version of this document was prepared by Vista Engineering for the SNF Project. The purpose of this revision is to document completion of verification actions that were pending at the time the initial report was prepared. Verification activities for the installed and operational SSCs have been completed. Verification of future additions to the CSB related to the canister cover cap and welding fixture system and MCO Internal Gas Sampling equipment will be completed as appropriate for those components. The open items related to verification of those requirements are noted

  19. Development of the OCRWM transportation geographic information system

    International Nuclear Information System (INIS)

    Peck, M. III; McGuinn, E.J.; Osborne, J.W.

    1995-01-01

    The U.S. Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) is responsible for disposing of the nation's high-level radioactive waste. Current plans call for OCRWM to ship commercial spent nuclear fuel (SNF) from 77 individual reactor sites to a central facility for disposal. The Transportation Geographic Information System (TGIS) is a valuable tool in planning for the SNF shipments and communicating with the public regarding the shipments. The TGIS consists of a geographic information system (GIS) combined with a set of databases that provide data on specific geographic areas, transportation networks, and point locations. Planning activities may include analyzing possible routing options or criteria, highlighting route-specific attributes such as the location of culturally sensitive areas, providing route-specific data such as accident statistics, determining the affected population density along a route to support risk assessment activities, or providing emergency response information such as responder locations and hospitals along the proposed routes. The TGIS is a useful communication tool in helping to address the public's concern over how the shipments will be managed, particularly in the area of route selection by providing graphic portrayals of potential routes in their true geographic contexts

  20. High Integrity Can Design Interfaces

    International Nuclear Information System (INIS)

    Shaber, E.L.

    1998-01-01

    The National Spent Nuclear Fuel Program is chartered with facilitating the disposition of DOE-owned spent nuclear fuel to allow disposal at a geologic repository. This is done through coordination with the repository program and by assisting DOE Site owners of SNF with needed information, standardized requirements, packaging approaches, etc. The High Integrity Can (HIC) will be manufactured to provide a substitute or barrier enhancement for normal fuel geometry and cladding. The can would be nested inside the DOE standardized canister which is designed to interface with the repository waste package. The HIC approach may provide the following benefits over typical canning approaches for DOE SNF. (a) It allows ready calculation and management of criticality issues for miscellaneous. (b) It segments and further isolates damaged or otherwise problem materials from normal SNF in the repository package. (c) It provides a very long term corrosion barrier. (d) It provides an extra internal pressure barrier for particulates, gaseous fission products, hydrogen, and water vapor. (e) It delays any potential release of fission products to the repository environment. (f) It maintains an additional level of fuel geometry control during design basis accidents, rock-fall, and seismic events. (g) When seal welded, it could provide the additional containment required for shipments involving plutonium content in excess of 20 Ci. (10 CFR 71.63.b) if integrated with an appropriate cask design. Long term corrosion protection is central to the HIC concept. The material selected for the HIC (Hastelloy C-22) has undergone extensive testing for repository service. The most severe theoretical interactions between iron, repository water containing chlorides and other repository construction materials have been tested. These expected chemical species have not been shown capable of corroding the selected HIC material. Therefore, the HIC should provide a significant barrier to DOE SNF dispersal

  1. Evaluation of severe accident risks, Grand Gulf, Unit 1: Main report

    International Nuclear Information System (INIS)

    Brown, T.D.; Breeding, R.J.; Jow, H.N.; Higgins, S.J.; Shiver, A.W.; Helton, J.C.; Amos, C.N.

    1990-12-01

    In support of the Nuclear Regulatory Commission's (NRC's) assessment of the risk from severe accidents at commercial nuclear power plants in the US report in NUREG-1150, the Severe Accident Risk Reduction Program (SARRP) has completed a revised calculation of the risk to the general public from severe accidents at the Grand Gulf Nuclear Station, Unit 1. This power plant, located in Port Gibson, Mississippi, is operated by the System Energy Resources, Inc. (SERI). The emphasis in this risk analysis was not on determining a ''so-called'' point estimate of risk. Rather, it was to determine the distribution of risk, and to discover the uncertainties that account for the breadth of this distribution. Off-site risk initiated by events internal to the power plant was assessed. 42 refs., 51 figs., 52 tabs

  2. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Executive summary: main report

    International Nuclear Information System (INIS)

    1975-10-01

    Information is presented concerning the objectives and organization of the reactor safety study; the basic concepts of risk; the nature of nuclear power plant accidents; risk assessment methodology; reactor accident risk; and comparison of nuclear risks to other societal risks

  3. The elements of a commercial human spaceflight safety reporting system

    Science.gov (United States)

    Christensen, Ian

    2017-10-01

    In its report on the SpaceShipTwo accident the National Transportation Safety Board (NTSB) included in its recommendations that the Federal Aviation Administration (FAA) ;in collaboration with the commercial spaceflight industry, continue work to implement a database of lessons learned from commercial space mishap investigations and encourage commercial space industry members to voluntarily submit lessons learned.; In its official response to the NTSB the FAA supported this recommendation and indicated it has initiated an iterative process to put into place a framework for a cooperative safety data sharing process including the sharing of lessons learned, and trends analysis. Such a framework is an important element of an overall commercial human spaceflight safety system.

  4. Ferritic Alloys as Accident Tolerant Fuel Cladding Material for Light Water Reactors

    International Nuclear Information System (INIS)

    Rebak, Raul B.

    2014-01-01

    The objective of the GE project is to demonstrate that advanced steels such as iron-chromium-aluminum (FeCrAl) alloys could be used as accident tolerant fuel cladding material in commercial light water reactors. The GE project does not include fuel development. Current findings support the concept that a FeCrAl alloy could be used for the cladding of commercial nuclear fuel. The use of this alloy will benefit the public since it is going to make the power generating light water reactors safer. In the Phase 1A of this cost shared project, GE (GRC + GNF) teamed with the University of Michigan, Los Alamos National Laboratory, Brookhaven National Laboratory, Idaho National Laboratory, and Oak Ridge National Laboratory to study the environmental and mechanical behavior of more than eight candidate cladding materials both under normal operation conditions of commercial nuclear reactors and under accident conditions in superheated steam (loss of coolant condition). The main findings are as follows: (1) Under normal operation conditions the candidate alloys (e.g. APMT, Alloy 33) showed excellent resistance to general corrosion, shadow corrosion and to environmentally assisted cracking. APMT also showed resistance to proton irradiation up to 5 dpa. (2) Under accident conditions the selected candidate materials showed several orders of magnitude improvement in the reaction with superheated steam as compared with the current zirconium based alloys. (3) Tube fabrication feasibility studies of FeCrAl alloys are underway. The aim is to obtain a wall thickness that is below 400 µm. (4) A strategy is outlined for the regulatory path approval and for the insertion of a lead fuel assembly in a commercial reactor by 2022. (5) The GE team worked closely with INL to have four rodlets tested in the ATR. GE provided the raw stock for the alloys, the fuel for the rodlets and the cost for fabrication/welding of the rodlets. INL fabricated the rodlets and the caps and welded them to

  5. Ferritic Alloys as Accident Tolerant Fuel Cladding Material for Light Water Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Rebak, Raul B. [General Electric Global Research, Schnectady, NY (United States)

    2014-09-30

    The objective of the GE project is to demonstrate that advanced steels such as iron-chromium-aluminum (FeCrAl) alloys could be used as accident tolerant fuel cladding material in commercial light water reactors. The GE project does not include fuel development. Current findings support the concept that a FeCrAl alloy could be used for the cladding of commercial nuclear fuel. The use of this alloy will benefit the public since it is going to make the power generating light water reactors safer. In the Phase 1A of this cost shared project, GE (GRC + GNF) teamed with the University of Michigan, Los Alamos National Laboratory, Brookhaven National Laboratory, Idaho National Laboratory, and Oak Ridge National Laboratory to study the environmental and mechanical behavior of more than eight candidate cladding materials both under normal operation conditions of commercial nuclear reactors and under accident conditions in superheated steam (loss of coolant condition). The main findings are as follows: (1) Under normal operation conditions the candidate alloys (e.g. APMT, Alloy 33) showed excellent resistance to general corrosion, shadow corrosion and to environmentally assisted cracking. APMT also showed resistance to proton irradiation up to 5 dpa. (2) Under accident conditions the selected candidate materials showed several orders of magnitude improvement in the reaction with superheated steam as compared with the current zirconium based alloys. (3) Tube fabrication feasibility studies of FeCrAl alloys are underway. The aim is to obtain a wall thickness that is below 400 µm. (4) A strategy is outlined for the regulatory path approval and for the insertion of a lead fuel assembly in a commercial reactor by 2022. (5) The GE team worked closely with INL to have four rodlets tested in the ATR. GE provided the raw stock for the alloys, the fuel for the rodlets and the cost for fabrication/welding of the rodlets. INL fabricated the rodlets and the caps and welded them to

  6. A methodology for analyzing precursors to earthquake-initiated and fire-initiated accident sequences

    International Nuclear Information System (INIS)

    Budnitz, R.J.; Lambert, H.E.; Apostolakis, G.

    1998-04-01

    This report covers work to develop a methodology for analyzing precursors to both earthquake-initiated and fire-initiated accidents at commercial nuclear power plants. Currently, the U.S. Nuclear Regulatory Commission sponsors a large ongoing project, the Accident Sequence Precursor project, to analyze the safety significance of other types of accident precursors, such as those arising from internally-initiated transients and pipe breaks, but earthquakes and fires are not within the current scope. The results of this project are that: (1) an overall step-by-step methodology has been developed for precursors to both fire-initiated and seismic-initiated potential accidents; (2) some stylized case-study examples are provided to demonstrate how the fully-developed methodology works in practice, and (3) a generic seismic-fragility date base for equipment is provided for use in seismic-precursors analyses. 44 refs., 23 figs., 16 tabs

  7. SNF AGING SYSTEM DESCRIPTION DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    L.L. Swanson

    2005-04-06

    The purpose of this system description document (SDD) is to establish requirements that drive the design of the spent nuclear fuel (SNF) aging system and associated bases, which will allow the design effort to proceed. This SDD will be revised at strategic points as the design matures. This SDD identifies the requirements and describes the system design, as it currently exists, with emphasis on attributes of the design provided to meet the requirements. This SDD is an engineering tool for design control; accordingly, the primary audience and users are design engineers. This SDD is part of an iterative design process. It leads the design process with regard to the flow down of upper tier requirements onto the system. Knowledge of these requirements is essential in performing the design process. The SDD follows the design with regard to the description of the system. The description provided in the SDD reflects the current results of the design process. Throughout this SDD, the term aging cask applies to vertical site-specific casks and to horizontal aging modules. The term overpack is a vertical site-specific cask that contains a dual-purpose canister (DPC) or a disposable canister. Functional and operational requirements applicable to this system were obtained from ''Project Functional and Operational Requirements'' (F&OR) (Curry 2004 [DIRS 170557]). Other requirements that support the design process were taken from documents such as ''Project Design Criteria Document'' (PDC) (BSC 2004 [DES 171599]), ''Site Fire Hazards Analyses'' (BSC 2005 [DIRS 172174]), and ''Nuclear Safety Design Bases for License Application'' (BSC 2005 [DIRS 171512]). The documents address requirements in the ''Project Requirements Document'' (PRD) (Canori and Leitner 2003 [DIRS 166275]). This SDD includes several appendices. Appendix A is a Glossary; Appendix B is a list of key system charts

  8. SNF AGING SYSTEM DESCRIPTION DOCUMENT

    International Nuclear Information System (INIS)

    L.L. Swanson

    2005-01-01

    The purpose of this system description document (SDD) is to establish requirements that drive the design of the spent nuclear fuel (SNF) aging system and associated bases, which will allow the design effort to proceed. This SDD will be revised at strategic points as the design matures. This SDD identifies the requirements and describes the system design, as it currently exists, with emphasis on attributes of the design provided to meet the requirements. This SDD is an engineering tool for design control; accordingly, the primary audience and users are design engineers. This SDD is part of an iterative design process. It leads the design process with regard to the flow down of upper tier requirements onto the system. Knowledge of these requirements is essential in performing the design process. The SDD follows the design with regard to the description of the system. The description provided in the SDD reflects the current results of the design process. Throughout this SDD, the term aging cask applies to vertical site-specific casks and to horizontal aging modules. The term overpack is a vertical site-specific cask that contains a dual-purpose canister (DPC) or a disposable canister. Functional and operational requirements applicable to this system were obtained from ''Project Functional and Operational Requirements'' (F andOR) (Curry 2004 [DIRS 170557]). Other requirements that support the design process were taken from documents such as ''Project Design Criteria Document'' (PDC) (BSC 2004 [DES 171599]), ''Site Fire Hazards Analyses'' (BSC 2005 [DIRS 172174]), and ''Nuclear Safety Design Bases for License Application'' (BSC 2005 [DIRS 171512]). The documents address requirements in the ''Project Requirements Document'' (PRD) (Canori and Leitner 2003 [DIRS 166275]). This SDD includes several appendices. Appendix A is a Glossary; Appendix B is a list of key system charts, diagrams, drawings, lists and additional supporting information; and Appendix C is a list of

  9. Safety Design Approach for the Development of Safety Requirements for Design of Commercial HTGR

    International Nuclear Information System (INIS)

    Ohashi, Hirofumi; Sato, Hiroyuki; Nakagawa, Shigeaki; Tachibana, Yukio; Nishihara, Tetsuo; Yan, Xing; Sakaba, Nariaki; Kunitomi, Kazuhiko

    2014-01-01

    The research committee on “Safety requirements for HTGR design” was established in 2013 under the Atomic Energy Society of Japan to develop the draft safety requirements for the design of commercial High Temperature Gas-cooled Reactors (HTGRs), which incorporate the HTGR safety features demonstrated using the High Temperature Engineering Test Reactor (HTTR), lessons learned from the accident of Fukushima Daiichi Nuclear Power Station and requirements for the integration of the hydrogen production plants. The safety design approach for the commercial HTGRs which is a basement of the safety requirements is determined prior to the development of the safety requirements. The safety design approaches for the commercial HTGRs are to confine the radioactive materials within the coated fuel particles not only during normal operation but also during accident conditions, and the integrity of the coated fuel particles and other requiring physical barriers are protected by the inherent and passive safety features. This paper describes the main topics of the research committee, the safety design approaches and the safety functions of the commercial HTGRs determined in the research committee. (author)

  10. Thermal Hydraulic Analysis of K-DEMO Single Blanket Module for Preliminary Accident Analysis using MELCOR

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Sung Bo; Bang, In Cheol [UNIST, Ulsan (Korea, Republic of)

    2016-05-15

    To develop the Korean fusion commercial reactor, preliminary design concept for K-DEMO (Korean fusion demonstration reactor) has been announced by NFRI (National Fusion Research Institute). This pre-conceptual study of K-DEMO has been introduced to identify technical details of a fusion power plant for the future commercialization of fusion reactor in Korea. Before this consideration, to build the K-DEMO, accident analysis is essential. Since the Fukushima accident, which is severe accident from unexpected disaster, safety analysis of nuclear power plant has become important. The safety analysis of both fission and fusion reactors is deemed crucial in demonstrating the low radiological effect of these reactors on the environment, during severe accidents. A risk analysis of K-DEMO should be performed, as a prerequisite for the construction of a fusion reactor. In this research, thermal-hydraulic analysis of single blanket module of K-DEMO is conducted for preliminary accident analysis for K-DEMO. Further study about effect of flow distributer is conducted. The normal K-DEMO operation condition is applied to the boundary condition and simulated to verify the material temperature limit using MELCOR. MELCOR is fully integrated, relatively fast-running code developed by Sandia National Laboratories. MELCOR had been used for Light Water Reactors and fusion reactor version of MELCOR was developed for ITER accident analysis. This study shows the result of thermal-hydraulic simulation of single blanket module with MELCOR which is severe accident code for nuclear fusion safety analysis. The difference of mass flow rate for each coolant channel with or without flow distributer is presented. With flow distributer, advantage of broadening temperature gradient in the K-DEMO blanket module and increase mass flow toward first wall is obtained. This can enhance the safety of K-DEMO blanket module. Most 13 .deg. C temperature difference in blanket module is obtained.

  11. Accident management insights after the Fukushima Daiichi NPP accident

    International Nuclear Information System (INIS)

    Degueldre, Didier; Viktorov, Alexandre; Tuomainen, Minna; Ducamp, Francois; Chevalier, Sophie; Guigueno, Yves; Tasset, Daniel; Heinrich, Marcus; Schneider, Matthias; Funahashi, Toshihiro; Hotta, Akitoshi; Kajimoto, Mitsuhiro; Chung, Dae-Wook; Kuriene, Laima; Kozlova, Nadezhda; Zivko, Tomi; Aleza, Santiago; Jones, John; McHale, Jack; Nieh, Ho; Pascal, Ghislain; ); Nakoski, John; Neretin, Victor; Nezuka, Takayoshi; )

    2014-01-01

    The Fukushima Daiichi nuclear power plant (NPP) accident, that took place on 11 March 2011, initiated a significant number of activities at the national and international levels to reassess the safety of existing NPPs, evaluate the sufficiency of technical means and administrative measures available for emergency response, and develop recommendations for increasing the robustness of NPPs to withstand extreme external events and beyond design basis accidents. The OECD Nuclear Energy Agency (NEA) is working closely with its member and partner countries to examine the causes of the accident and to identify lessons learnt with a view to the appropriate follow-up actions to be taken by the nuclear safety community. Accident management is a priority area of work for the NEA to address lessons being learnt from the accident at the Fukushima Daiichi NPP following the recommendations of Committee on Nuclear Regulatory Activities (CNRA), Committee on the Safety of Nuclear Installations (CSNI), and Committee on Radiation Protection and Public Health (CRPPH). Considering the importance of these issues, the CNRA authorised the formation of a task group on accident management (TGAM) in June 2012 to review the regulatory framework for accident management following the Fukushima Daiichi NPP accident. The task group was requested to assess the NEA member countries needs and challenges in light of the accident from a regulatory point of view. The general objectives of the TGAM review were to consider: - enhancements of on-site accident management procedures and guidelines based on lessons learnt from the Fukushima Daiichi NPP accident; - decision-making and guiding principles in emergency situations; - guidance for instrumentation, equipment and supplies for addressing long-term aspects of accident management; - guidance and implementation when taking extreme measures for accident management. The report is built on the existing bases for capabilities to respond to design basis

  12. The Chernobyl accident: Causes and consequences

    International Nuclear Information System (INIS)

    Malinauskas, A.P.

    1987-01-01

    Two explosions, one immediately following the other, in Unit 4 of the Chernobyl nuclear power station in the Soviet Union signaled the worst disaster ever to befall the commercial nuclear power production industry. This accident, which occurred at 1:24 a.m. on April 26, 1986, resulted from an almost incredible series of operational errors associated, ironically, with an attempt to enhance the capability of the reactor to safely accommodate station blackout accidents (i.e., accidents arising from a loss of station electrical power). Disruption of the core, due to a prompt criticality excursion, resulted in the destruction of the core vault and reactor building and the sudden dispersal of about 3% of the fuel from the core region into the environment. Lesser but significant releases of radioactivity continued through May 6, 1986, before attempts to certain the radioactivity and cool the remnants of the core were successful. The amount and composition of material released in the course of the accident remain somewhat uncertain, and inconsistencies in the release estimates are evident. The Soviet estimates, in addition to the dispersal of about 3% of the fuel, include complete release of the noble gas core inventory, 20% of the fission product iodine inventory, 15% of the tellurium inventory, and 10 to 13% of the fission product cesium inventory. The iodine and cesium release estimates are not consistent with the noble gas values, and are as much as a factor of two less than some estimates made by experts outside the Soviet Union

  13. The Question of Queue: Implications for -Best Practice- in Cross-country Transport of Commercial Spent Nuclear Fuel

    International Nuclear Information System (INIS)

    Williams, J.M.

    2009-01-01

    The 'Standard Contract' authorized by the Nuclear Waste Policy Act of 1982 (Section 302(a)) provides that priority for acceptance of spent nuclear fuel (SNF) shall be based on the date of its discharge from civilian nuclear reactors. Through 2007, about 2,100 discharges of about 58,000 metric tons have created a priority ranking (or 'queue') for US DOE spent fuel acceptance and transport. Since 1982, consideration of the task of large-scale, cross-country SNF transport (by the National Academies and others) has led to several recommendations for 'best practice' in such an unprecedented campaign. Many of these recommendations, however, are inconsistent with the acceptance priority established by the Standard Contract, and in fact cannot be implemented under its provisions. This paper considers the SNF acceptance rankings established by the Standard Contract, and the barrier these place on best practice cross-country transport of the nation's inventory of SNF. Using a series of case studies, the paper explores the challenge of best practice transport from selected shipment origins under current arrangements. The case studies support preliminary conclusions regarding the inconsistency between best practice SNF transport and the Standard Contract acceptance queue, with reference to particular origins sites and their utility owners. The paper concludes with a suggestion for resolving the inconsistencies, and recommended next steps in the inquiry. (authors)

  14. The relationship between driving simulation performance and obstructive sleep apnoea risk, daytime sleepiness, obesity and road traffic accident history of commercial drivers in Turkey.

    Science.gov (United States)

    Demirdöğen Çetinoğlu, Ezgi; Görek Dilektaşlı, Aslı; Demir, Nefise Ateş; Özkaya, Güven; Acet, Nilüfer Aylin; Durmuş, Eda; Ursavaş, Ahmet; Karadağ, Mehmet; Ege, Ercüment

    2015-09-01

    Driving performance is known to be very sensitive to cognitive-psychomotor impairment. The aim of the study was to determine the relationship between obesity, risk of obstructive sleep apnoea (OSA), daytime sleepiness, history of road traffic accident (RTA) and performance on a driving simulator, among commercial drivers. We examined commercial vehicle drivers admitted to Psycho-Technical Assessment System (PTAS), which is a computer-aided system that includes a driving simulator test and tests assessing psychomotor-cognitive skills required for driving. Risk of OSA and daytime sleepiness were assessed by the Berlin Questionnaire and the Epworth Sleepiness Scale (ESS), respectively. A total of 282 commercial vehicle drivers were consecutively enrolled. The age range was 29-76 years. Thirty drivers were at high risk of OSA. Median ESS of the group was 2 (0-20). Forty-seven percent of the subjects at high risk of OSA failed in early reaction time test, while 28% of the drivers with low risk of OSA failed (p = 0.03). The obese drivers failed the peripheral vision test when compared with non-obese drivers (p = 0.02). ESS was higher for drivers with a history of RTA when compared to those without RTA (p = 0.02). Cognitive-psychomotor functions can be impaired in obese and high risk of OSA patients. In our opinion, requiring obese and/or high risk of OSA drivers to take PTAS tests that assess driving skills and psychomotor-cognitive functions crucial to those skills would significantly improve road traffic safety, which is of considerable importance to public health.

  15. Levels of safety satisfactory for commercialization of the breeder

    International Nuclear Information System (INIS)

    Ferguson, R.L.

    1979-01-01

    A brief discussion is presented of the Department of Energy's LMFBR safety program and the safety levels which DOE believes would be satisfactory for the commercialization of the breeder are indicated. Some observations are offered on the Three Mile Island accident and some of its implications are discussed for the LMFBR program

  16. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Appendix VI. Calculation of reactor accident consequences

    International Nuclear Information System (INIS)

    1975-10-01

    Information is presented concerning the radioactive releases from the containment following accidents; radioactive inventory of the reactor core; atmospheric dispersion; reactor sites and meteorological data; radioactive decay and deposition from plumes; finite distance of plume travel; dosimetric models; health effects; demographic data; mitigation of radiation exposure; economic model; and calculated results with consequence model

  17. Motorcycles Health and Traffic Safety: Evidence from Commercial Motorcyclists in Gombe State, Nigeria

    Directory of Open Access Journals (Sweden)

    Nasiru Inuwa

    2017-04-01

    Full Text Available Although commercial motorcyclists are gaining acceptance by all and sundry as a means of public transport which are adapted to the contemporary Nigerian society. However, expose to all hazards including accidents are further worsened by the lack of proper knowledge on road safety measures of the commercial motorcycle riders. Therefore, this study evaluates the effects of a commercial motorcycle on health and traffic safety in Gombe metropolis, Gombe State, Nigeria. The study was carried out in Gombe Metropolis with using the random sampling technique to select 500 motorcyclists sample size. The data generated were analyzed using simple percentages. The study finds that most of the motorcycles accidents were caused by reckless riding, drug abuse and disregard to traffic rules. Similarly, the study finds that Tricycles are the most important factor causing motorcycle accidents in Gombe metropolis. Furthermore, the study finds that most of the respondents suffer from at least one health challenge as a result of their continuous use of the motorcycle. The study therefore recommends that government and other relevant agencies should be equipped with materials and human resources to embark on regular and massive breath testing of motorcyclists to detect riders who ride under the influence of drugs. This can be achieved through identifying the Drunken riders and make them face the wrath of the law.

  18. Unavoidable Accident

    OpenAIRE

    Grady, Mark F.

    2009-01-01

    In negligence law, "unavoidable accident" is the risk that remains when an actor has used due care. The counterpart of unavoidable accident is "negligent harm." Negligence law makes parties immune for unavoidable accident even when they have used less than due care. Courts have developed a number of methods by which they "sort" accidents to unavoidable accident or to negligent harm, holding parties liable only for the latter. These sorting techniques are interesting in their own right and als...

  19. Status of Progress Made Toward Safety Analysis and Technical Site Evaluations for DOE Managed HLW and SNF.

    Energy Technology Data Exchange (ETDEWEB)

    Sevougian, S. David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Stein, Emily [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gross, Michael B [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hammond, Glenn Edward [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Frederick, Jennifer M [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mariner, Paul [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-11-01

    The Spent Fuel and Waste Science and Technology (SFWST) Campaign of the U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) is conducting research and development (R&D) on generic deep geologic disposal systems (i.e., repositories). This report describes specific activities in FY 2016 associated with the development of a Defense Waste Repository (DWR)a for the permanent disposal of a portion of the HLW and SNF derived from national defense and research and development (R&D) activities of the DOE.

  20. Modelling Accident Tolerant Fuel Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Hales, Jason Dean [Idaho National Laboratory; Gamble, Kyle Allan Lawrence [Idaho National Laboratory

    2016-05-01

    The catastrophic events that occurred at the Fukushima-Daiichi nuclear power plant in 2011 have led to widespread interest in research of alternative fuels and claddings that are proposed to be accident tolerant. The United States Department of Energy (DOE) through its Nuclear Energy Advanced Modeling and Simulation (NEAMS) program has funded an Accident Tolerant Fuel (ATF) High Impact Problem (HIP). The ATF HIP is a three-year project to perform research on two accident tolerant concepts. The final outcome of the ATF HIP will be an in-depth report to the DOE Advanced Fuels Campaign (AFC) giving a recommendation on whether either of the two concepts should be included in their lead test assembly scheduled for placement into a commercial reactor in 2022. The two ATF concepts under investigation in the HIP are uranium silicide fuel and iron-chromium-aluminum (FeCrAl) alloy cladding. Utilizing the expertise of three national laboratory participants (Idaho National Laboratory, Los Alamos National Laboratory, and Argonne National Laboratory), a comprehensive multiscale approach to modeling is being used that includes atomistic modeling, molecular dynamics, rate theory, phase-field, and fuel performance simulations. Model development and fuel performance analysis are critical since a full suite of experimental studies will not be complete before AFC must prioritize concepts for focused development. In this paper, we present simulations of the two proposed accident tolerance fuel systems: U3Si2 fuel with Zircaloy-4 cladding, and UO2 fuel with FeCrAl cladding. Sensitivity analyses are completed using Sandia National Laboratories’ Dakota software to determine which input parameters (e.g., fuel specific heat) have the greatest influence on the output metrics of interest (e.g., fuel centerline temperature). We also outline the multiscale modelling approach being employed. Considerable additional work is required prior to preparing the recommendation report for the Advanced

  1. Domino effect in chemical accidents: main features and accident sequences

    OpenAIRE

    Casal Fàbrega, Joaquim; Darbra Roman, Rosa Maria

    2010-01-01

    The main features of domino accidents in process/storage plants and in the transportation of hazardous materials were studied through an analysis of 225 accidents involving this effect. Data on these accidents, which occurred after 1961, were taken from several sources. Aspects analyzed included the accident scenario, the type of accident, the materials involved, the causes and consequences and the most common accident sequences. The analysis showed that the most frequent causes a...

  2. Impacts on the marine environment in the case of a hypothetical accident involving the recovery of the dumped Russian submarine K-27, based on dispersion of 137Cs.

    Science.gov (United States)

    Hosseini, A; Amundsen, I; Brown, J; Dowdall, M; Karcher, M; Kauker, F; Schnur, R

    2017-02-01

    There is increasing concern regarding the issue of dumped nuclear waste in the Arctic Seas and in particular dumped objects with Spent Nuclear Fuel (SNF). Amongst dumped objects in the Arctic, the dumped Russian submarine K-27 has received great attention as it contains two reactors with highly enriched fuel and lies at a depth of about 30 m under water. To address these concerns a health and environmental impact assessment has been undertaken. Marine dispersion of potentially released radionuclides as a consequence of different hypothetical accident scenarios was modelled using the model NAOSIM. The outputs from the dispersion modelling have been used as inputs to food-chain transfer and environmental dosimetry models. The annual effective doses for subsistence fishing communities of the Barents-Kara seas region do not exceed 0.6 mSv for hypothetical accidents located at Stepovogo fjord or the Barents Sea. For high rate consumers of fish in Norway, following a potential accident at the Gremikha Bay, annual effects doses would be at around 0.15 mSv. Accumulated doses (over 90 days) for various organisms and for all release scenarios considered were never in excess of 150 μGy. The levels of 137 Cs derived for marine organism in areas close to Norway were not values that would likely cause concern from a regulatory perspective although for subsistence fishing communities close to the considered accident locations, it is not inconceivable that some restrictions on fishing etc. would need to be introduced. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. MELCOR Severe Accident Analysis on the SMART Reactor

    International Nuclear Information System (INIS)

    Kim, Tae Woon; Jin, Young Ho; Kim, Young In; Kim, Keung Koo; Wang, Ziao; Revankar, Shripad

    2014-01-01

    A severe accident is analyzed for Korea SMR reactor, SMART. Core melt down sequences are analyzed for SMART reactor core using MELCOR version 1.8.5. MELCOR is developed by Sandia National Laboratory for US NRC for the simulation of severe accidents in nuclear power plants. Two cases are simulated here and compared between them; one is the case for core having 3 concentric rings and the other is the case for core having 5 concentric rings. One inch break LOCA scenario is simulated and compared between these two core models. Time sequences for the thermal hydraulic behaviors of RPV and thermal heatup behaviors of reactor core are explained in graphically. Thermal hydraulic behavior such as the change of pressure, level, mass, and temperature of RPV is explained. Thermal heatup behavior of reactor core such as oxidation of cladding, hydrogen generation, core slumping down to lower plenum, and finally creep rupture of PRV lower head is explained. Engineered safety features such as safety injection systems (SIS), and Passive residual heat removal systems (PHRS), etc. are assumed to be not working. One inch break of severe accident is simulated on Korean SMR (SMART) Integral PWR with MELCOR code version 1.8.5. Core melt progression and lower head failure time is very slow compared to other commercial reactors. Simulation on 3 and 5 radial rings core models gives very similar pattern in core cell failure timings. Other various accident scenarios (for example, SBO in Fukushima) will be tried further. Containment behaviors and source term behaviors in severe accident conditions will be analyzed in future

  4. Stress in accident and post-accident management at Chernobyl

    International Nuclear Information System (INIS)

    Girard, P.; Dubreuil, G.H.

    1996-01-01

    The effects of the Chernobyl nuclear accident on the psychology of the affected population have been much discussed. The psychological dimension has been advanced as a factor explaining the emergence, from 1990 onwards, of a post-accident crisis in the main CIS countries affected. This article presents the conclusions of a series of European studies, which focused on the consequences of the Chernobyl accident. These studies show that the psychological and social effects associated with the post-accident situation arise from the interdependency of a number of complex factors exerting a deleterious effect on the population. We shall first attempt to characterise the stress phenomena observed among the population affected by the accident. Secondly, we will be presenting an anlysis of the various factors that have contributed to the emerging psychological and social features of population reaction to the accident and in post-accident phases, while not neglecting the effects of the pre-accident situation on the target population. Thirdly, we shall devote some initial consideration to the conditions that might be conducive to better management of post-accident stress. In conclusion, we shall emphasise the need to restore confidence among the population generally. (Author)

  5. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Appendices VII, VIII, IX, and X

    International Nuclear Information System (INIS)

    1975-10-01

    Information is presented concerning the release of radioactivity in reactor accidents; physical processes in reactor meltdown accidents; safety design rationale for nuclear power plants; and design adequacy

  6. Spent Nuclear Fuel (SNF) Project Cask and MCO Helium Purge System Design Review Completion Report - Project A.5 and A.6

    International Nuclear Information System (INIS)

    ARD, K.E.

    2000-01-01

    This report documents the results of the design verification performed on the Cask and Multiple Canister Over-pack (MCO) Helium Purge System. The helium purge system is part of the Spent Nuclear Fuel (SNF) Project Cask Loadout System (CLS) at 100K area. The design verification employed the ''Independent Review Method'' in accordance with Administrative Procedure (AP) EN-6-027-01

  7. Substance use among Iranian drivers involved in fatal road accidents

    Directory of Open Access Journals (Sweden)

    Shervin eAssari

    2014-08-01

    Full Text Available Background: Although the problem of substance use among drivers is not limited to a special part of the world, most published epidemiological reports on this topic is from industrial world.Aim: To determine drug use among Iranian adults who were imprisoned for vehicle accidents with fatality. Methods: This study enrolled 51 Iranian adults who were imprisoned for vehicle accidents with fatality. This sample came from a national survey of prisoners. Data was collected at entry to prisons during the last 4 months of 2008 in 7 prisons in different parts of the country. Self reported drug use was registered. Commercial substance use screening tests were also done. Results: Drug test was positive for opioids, cannabis and both in 37.3%, 2.0% and 13.7%, respectively. 29.4% tested positive for benzodiazepines. Using test introduced 23.5% of our sample as drug users, who had declined to report any drug use. Conclusion: Opioids are the most used illicit drug in the case of vehicle accidents with fatality, however, 20% of users do not declare their use. This high rate of drug use in vehicle accidents with fatality reflects the importance of drug use control as a part of injury prevention in Iran. There might be a need for drug screening after severe car accidents.

  8. Fitness to drive among commercial intercity drivers in Benin-City ...

    African Journals Online (AJOL)

    Background: Unfit drivers are prone to road traffic accident, therefore their health is paramount in ensuring the safety of road users. To determine the fitness to drive among commercial intercity bus drivers in Benin City, Edo State Material and methods: A descriptive cross-sectional study was conducted among 194 ...

  9. Accident sequence precursor analysis level 2/3 model development

    International Nuclear Information System (INIS)

    Lui, C.H.; Galyean, W.J.; Brownson, D.A.

    1997-01-01

    The US Nuclear Regulatory Commission's Accident Sequence Precursor (ASP) program currently uses simple Level 1 models to assess the conditional core damage probability for operational events occurring in commercial nuclear power plants (NPP). Since not all accident sequences leading to core damage will result in the same radiological consequences, it is necessary to develop simple Level 2/3 models that can be used to analyze the response of the NPP containment structure in the context of a core damage accident, estimate the magnitude of the resulting radioactive releases to the environment, and calculate the consequences associated with these releases. The simple Level 2/3 model development work was initiated in 1995, and several prototype models have been completed. Once developed, these simple Level 2/3 models are linked to the simple Level 1 models to provide risk perspectives for operational events. This paper describes the methods implemented for the development of these simple Level 2/3 ASP models, and the linkage process to the existing Level 1 models

  10. Criticality issues with highly enriched fuels in a repository environment

    International Nuclear Information System (INIS)

    Taylor, L.L.; Sanchez, L.C.; Rath, J.S.

    1998-03-01

    This paper presents preliminary analysis of a volcanic tuff repository containing a combination of low enrichment commercial spent nuclear fuels (SNF) and DOE-owned SNF packages. These SNFs were analyzed with respect to their criticality risks. Disposal of SNF packages containing significant fissile mass within a geologic repository must comply with current regulations relative to criticality safety during transportation and handling within operational facilities. However, once the repository is closed, the double contingency credits for criticality safety are subject to unremediable degradation, (e.g., water intrusion, continued presence of neutron absorbers in proximity to fissile material, and fissile material reconfiguration). The work presented in this paper focused on two attributes of criticality in a volcanic tuff repository for near-field and far-field scenarios: (1) scenario conditions necessary to have a criticality, and (2) consequences of a nuclear excursion that are components of risk. All criticality consequences are dependent upon eventual water intrusion into the repository and subsequent breach of the disposal package. Key criticality parameters necessary for a critical assembly are: (1) adequate thermal fissile mass, (2) adequate concentration of fissile material, (3) separation of neutron poison from fissile materials, and (4) sufficient neutron moderation (expressed in units of moderator to fissile atom ratios). Key results from this study indicated that the total energies released during a single excursion are minimal (comparable to those released in previous solution accidents), and the maximum frequency of occurrence is bounded by the saturation and temperature recycle times, thus resulting in small criticality risks

  11. Self-reported accidents

    DEFF Research Database (Denmark)

    Møller, Katrine Meltofte; Andersen, Camilla Sloth

    2016-01-01

    The main idea behind the self-reporting of accidents is to ask people about their traffic accidents and gain knowledge on these accidents without relying on the official records kept by police and/or hospitals.......The main idea behind the self-reporting of accidents is to ask people about their traffic accidents and gain knowledge on these accidents without relying on the official records kept by police and/or hospitals....

  12. Sudden illness while driving a vehicle--a retrospective analysis of commercial drivers in Japan.

    Science.gov (United States)

    Hitosugi, Masahito; Gomei, Sayaka; Okubo, Takao; Tokudome, Shogo

    2012-01-01

    We performed a retrospective analysis of commercial drivers to clarify the background of incidents of sudden illness while driving. The analysis used reports submitted by employers to the Japan Ministry of Land, Infrastructure, Transport, and Tourism regarding commercial drivers who had been ordered to stop driving owing to health problems. Of 211 cases with an average work history of 15.2 years, there were 88 bus drivers, 70 taxi drivers, and 53 truck drivers, 36.0% of who had died as a result of their disease. Among taxi and truck drivers, more than 70% of incidents were due to cardiac, aortic, and cerebrovascular disease. More than 80% of these were unable to avoid traffic accidents caused by sudden illness. However, among bus drivers, cardiac, aortic, and cerebrovascular disease accounted for only 23.5% of incidents, and accidents were avoided in more than half of the cases. The duration between starting work and the incident time was significantly shorter among bus drivers [mean 3.3 hours, standard deviation (SD) 3.1] than taxi (7.7 hours, SD 5.8) and truck (7.2 hours, SD 6.3) drivers (Pprevent disabling events while driving. As a precaution, physicians should advise commercial drivers to stop driving as soon as they detect slight discomfort. To prevent accidents, more assertive health promotion aimed at professional drivers is needed.

  13. Accident Assessment

    International Nuclear Information System (INIS)

    Tripputi, Ivo; Lund, Ingemar

    2002-01-01

    There is a general feeling that decommissioning is an activity involving limited risks, compared to NPP operation, and in particular risks involving the general public. This is technically confirmed by licensing analysis and evaluations, where, once the spent fuel has been removed from the plant, the radioactivity inventory available to be released to the environment is very limited. Decommissioning activities performed so far in the world have also confirmed the first assumptions and no specific issue has been identified, in this field, to justify a completely new approach. Commercial interests in international harmonization, which could drive an in-depth discussion about the bases of this approach, are weak at the moment. However, there are several reasons why a discussion in an international framework about the Safety Case for decommissioning (and, in particular, about Accident Assessment) may be considered necessary and important, and why it may show some specific and peculiar aspects. An effort for a comprehensive and systematic D and D accident safety assessment of the decommissioning process is justified. It is necessary also to explore in a holistic way the aspects of industrial safety, and develop tools for the decision-making process optimization. The expected results are the implementation of appropriate and optimized protective measures in any event and of adequate on/off-site emergency plans for optimal public and workers protection. The experience from other decommissioning projects and large-scale industrial activities is essential to balance provisions and an Operating Experience review process (specific for decommissioning) should help to focus on real issues

  14. Analysis of legal arrangements concerning the control and monitoring of the contamination of soils, food products and commercial products in Belarus

    International Nuclear Information System (INIS)

    Bataille, C.; Crouail, P.

    2005-01-01

    After having recalled the management of emergency from April to May 1986, this report describes some aspects of the post-accident management in Soviet Union from June 1986 to 1991: dose limits and zoning, farming practices, consumption standards, commercialization standards. It describes the legal context implemented in Belarus from 1991 (two laws addressed the legal status of contaminated areas and the protection of people affected by the Chernobyl accident), and the evolutions since 1991 in terms of soil contamination and zoning, consumption and commercialization standards

  15. Management of Hanford Site non-defense production reactor spent nuclear fuel, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1997-03-01

    The US Department of Energy (DOE) needs to provide radiologically, and industrially safe and cost-effective management of the non-defense production reactor spent nuclear fuel (SNF) at the Hanford Site. The proposed action would place the Hanford Site's non-defense production reactor SNF in a radiologically- and industrially-safe, and passive storage condition pending final disposition. The proposed action would also reduce operational costs associated with storage of the non-defense production reactor SNF through consolidation of the SNF and through use of passive rather than active storage systems. Environmental, safety and health vulnerabilities associated with existing non-defense production reactor SNF storage facilities have been identified. DOE has determined that additional activities are required to consolidate non-defense production reactor SNF management activities at the Hanford Site, including cost-effective and safe interim storage, prior to final disposition, to enable deactivation of facilities where the SNF is now stored. Cost-effectiveness would be realized: through reduced operational costs associated with passive rather than active storage systems; removal of SNF from areas undergoing deactivation as part of the Hanford Site remediation effort; and eliminating the need to duplicate future transloading facilities at the 200 and 400 Areas. Radiologically- and industrially-safe storage would be enhanced through: (1) removal from aging facilities requiring substantial upgrades to continue safe storage; (2) utilization of passive rather than active storage systems for SNF; and (3) removal of SNF from some storage containers which have a limited remaining design life. No substantial increase in Hanford Site environmental impacts would be expected from the proposed action. Environmental impacts from postulated accident scenarios also were evaluated, and indicated that the risks associated with the proposed action would be small

  16. Arabian, Asian, western: a cross-cultural comparison of aircraft accidents from human factor perspectives.

    Science.gov (United States)

    Al-Wardi, Yousuf

    2017-09-01

    Rates of aviation accident differ in different regions; and national culture has been implicated as a factor. This invites a discussion about the role of national culture in aviation accidents. This study makes a cross-cultural comparison between Oman, Taiwan and the USA. A cross-cultural comparison was acquired using data from three studies, including this study, by applying the Human Factors Analysis and Classification System (HFACS) framework. The Taiwan study presented 523 mishaps with 1762 occurrences of human error obtained from the Republic of China Air Force. The study from the USA carried out for commercial aviation had 119 accidents with 245 instances of human error. This study carried out in Oman had a total of 40 aircraft accidents with 129 incidences. Variations were found between Oman, Taiwan and the USA at the levels of organisational influence and unsafe supervision. Seven HFACS categories showed significant differences between the three countries (p culture can have an impact on aviation safety. This study revealed that national culture plays a role in aircraft accidents related to human factors that cannot be disregarded.

  17. Major Accidents (Gray Swans) Likelihood Modeling Using Accident Precursors and Approximate Reasoning.

    Science.gov (United States)

    Khakzad, Nima; Khan, Faisal; Amyotte, Paul

    2015-07-01

    Compared to the remarkable progress in risk analysis of normal accidents, the risk analysis of major accidents has not been so well-established, partly due to the complexity of such accidents and partly due to low probabilities involved. The issue of low probabilities normally arises from the scarcity of major accidents' relevant data since such accidents are few and far between. In this work, knowing that major accidents are frequently preceded by accident precursors, a novel precursor-based methodology has been developed for likelihood modeling of major accidents in critical infrastructures based on a unique combination of accident precursor data, information theory, and approximate reasoning. For this purpose, we have introduced an innovative application of information analysis to identify the most informative near accident of a major accident. The observed data of the near accident were then used to establish predictive scenarios to foresee the occurrence of the major accident. We verified the methodology using offshore blowouts in the Gulf of Mexico, and then demonstrated its application to dam breaches in the United Sates. © 2015 Society for Risk Analysis.

  18. Domino effect in chemical accidents: main features and accident sequences.

    Science.gov (United States)

    Darbra, R M; Palacios, Adriana; Casal, Joaquim

    2010-11-15

    The main features of domino accidents in process/storage plants and in the transportation of hazardous materials were studied through an analysis of 225 accidents involving this effect. Data on these accidents, which occurred after 1961, were taken from several sources. Aspects analyzed included the accident scenario, the type of accident, the materials involved, the causes and consequences and the most common accident sequences. The analysis showed that the most frequent causes are external events (31%) and mechanical failure (29%). Storage areas (35%) and process plants (28%) are by far the most common settings for domino accidents. Eighty-nine per cent of the accidents involved flammable materials, the most frequent of which was LPG. The domino effect sequences were analyzed using relative probability event trees. The most frequent sequences were explosion→fire (27.6%), fire→explosion (27.5%) and fire→fire (17.8%). Copyright © 2010 Elsevier B.V. All rights reserved.

  19. Reducing health care hazards: lessons from the commercial aviation safety team.

    Science.gov (United States)

    Pronovost, Peter J; Goeschel, Christine A; Olsen, Kyle L; Pham, Julius C; Miller, Marlene R; Berenholtz, Sean M; Sexton, J Bryan; Marsteller, Jill A; Morlock, Laura L; Wu, Albert W; Loeb, Jerod M; Clancy, Carolyn M

    2009-01-01

    The movement to improve quality of care and patient safety has grown, but examples of measurable and sustained progress are rare. The slow progress made in health care contrasts with the success of aviation safety. After a tragic 1995 plane crash, the aviation industry and government created the Commercial Aviation Safety Team to reduce fatal accidents. This public-private partnership of safety officials and technical experts is responsible for the decreased average rate of fatal aviation accidents. We propose a similar partnership in the health care community to coordinate national efforts and move patient safety and quality forward.

  20. Brief Overlook on the Occupational Accidents Occurring During the Geotechnical Site Works

    Science.gov (United States)

    Akboğa Kale, Özge; Eskişar, Tuğba

    2017-10-01

    The aim of this paper is to evaluate occupational accidents reported in geotechnical site works. Variables of the accidents are categorized as the year and month of accidents, the technical codes used for defining the scope of work trades, end use and project type and cost, nature and cause of accidents, occupation of the victims and finally the cause of fatality. As a result, it is seen that the majority of victims were construction laborers or in special trade constructors who were working on a new project or new additions to an existing project. The geotechnical phase of the projects was whether excavation, landfill, sewer-water treatment, pipeline construction, commercial building or road construction. As the outcomes of the study it is evaluated that excavation, trenching and installing pipe or pile driving were the main causes of the accidents while trench collapse, struck by a falling object / projectile and wall collapse were the main causes of fatality. Moreover, it is established that more than half of the fatalities were due to asphyxia followed by fracture. These findings show that accidents occurred in geotechnical works do not only have high frequency but also high severity. This study emphasizes project specific countermeasures should be taken regarding the nature, cost and importance of the project and the occupation variabilities working on the project.

  1. Accident information needs

    International Nuclear Information System (INIS)

    Hanson, D.J.; Arcieri, W.C.; Ward, L.W.

    1992-01-01

    A Five-step methodology has been developed to evaluate information needs for nuclear power plants under accident conditions and the availability of plant instrumentation during severe accidents. Step 1 examines the credible accidents and their relationships to plant safety functions. Step 2 determines the information personnel involved in accident management will need to understand plant behavior. Step 3 determines the capability of the instrumentation to function properly under severe accident conditions. Step 4 determines the conditions expected during the identified severe accidents. Step 5 compares the instrument capabilities and the severe accident conditions to evaluate the availability of the instrumentation to supply needed plant information

  2. Accident information needs

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, D.J.; Arcieri, W.C.; Ward, L.W.

    1992-12-31

    A Five-step methodology has been developed to evaluate information needs for nuclear power plants under accident conditions and the availability of plant instrumentation during severe accidents. Step 1 examines the credible accidents and their relationships to plant safety functions. Step 2 determines the information personnel involved in accident management will need to understand plant behavior. Step 3 determines the capability of the instrumentation to function properly under severe accident conditions. Step 4 determines the conditions expected during the identified severe accidents. Step 5 compares the instrument capabilities and the severe accident conditions to evaluate the availability of the instrumentation to supply needed plant information.

  3. Accident information needs

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, D.J.; Arcieri, W.C.; Ward, L.W.

    1992-01-01

    A Five-step methodology has been developed to evaluate information needs for nuclear power plants under accident conditions and the availability of plant instrumentation during severe accidents. Step 1 examines the credible accidents and their relationships to plant safety functions. Step 2 determines the information personnel involved in accident management will need to understand plant behavior. Step 3 determines the capability of the instrumentation to function properly under severe accident conditions. Step 4 determines the conditions expected during the identified severe accidents. Step 5 compares the instrument capabilities and the severe accident conditions to evaluate the availability of the instrumentation to supply needed plant information.

  4. Nuclear power plant safety - the risk of accidents

    International Nuclear Information System (INIS)

    Higson, D.; Crancher, D.W.

    1975-08-01

    Although it is physically impossible for any nuclear plant to explode like an atom bomb, an accidental release of radioactive material into the environment is conceivable. Three factors reduce the probability of such releases, in dangerous quantities, to an extremely low level. Firstly, there are many safety features built into the plant including a leaktight containment building to prevent the escape of such material. Secondly, the quality of engineering and standards used are far more demanding than in conventional power engineering. Thirdly, strict government licensing and regulatory control is enforced at all phases from design through construction to operation. No member of the general public is known to have been injured or died as a result of any accident to a commercial nuclear power plant. Ten workers have died as a result of over-exposure to radiation from experimental reactors and laboratory work connected with the development of nuclear plant since 1945. Because of this excellent safety record the risk of serious accidents can only be estimated. On the basis of such estimates, the chance of an accident in a nuclear power reactor which could cause a detectable increase in the incidence of radiation-induced illnesses would be less than one chance in a million per year. In a typical highly industrialised society, such as the USA, the estimated risk of an individual being killed by such accidents, from one hundred operating reactors, is no greater than one chance in sixteen million per year. There are undoubtedly risks from reactor accidents but estimates of these risks show that they are considerably less than from other activities which are accepted by society. (author)

  5. Learning lessons from Natech accidents - the eNATECH accident database

    Science.gov (United States)

    Krausmann, Elisabeth; Girgin, Serkan

    2016-04-01

    When natural hazards impact industrial facilities that house or process hazardous materials, fires, explosions and toxic releases can occur. This type of accident is commonly referred to as Natech accident. In order to prevent the recurrence of accidents or to better mitigate their consequences, lessons-learned type studies using available accident data are usually carried out. Through post-accident analysis, conclusions can be drawn on the most common damage and failure modes and hazmat release paths, particularly vulnerable storage and process equipment, and the hazardous materials most commonly involved in these types of accidents. These analyses also lend themselves to identifying technical and organisational risk-reduction measures that require improvement or are missing. Industrial accident databases are commonly used for retrieving sets of Natech accident case histories for further analysis. These databases contain accident data from the open literature, government authorities or in-company sources. The quality of reported information is not uniform and exhibits different levels of detail and accuracy. This is due to the difficulty of finding qualified information sources, especially in situations where accident reporting by the industry or by authorities is not compulsory, e.g. when spill quantities are below the reporting threshold. Data collection has then to rely on voluntary record keeping often by non-experts. The level of detail is particularly non-uniform for Natech accident data depending on whether the consequences of the Natech event were major or minor, and whether comprehensive information was available for reporting. In addition to the reporting bias towards high-consequence events, industrial accident databases frequently lack information on the severity of the triggering natural hazard, as well as on failure modes that led to the hazmat release. This makes it difficult to reconstruct the dynamics of the accident and renders the development of

  6. CONTAINMENT ANALYSIS METHODOLOGY FOR TRANSPORT OF BREACHED CLAD ALUMINUM SPENT FUEL

    Energy Technology Data Exchange (ETDEWEB)

    Vinson, D.

    2010-07-11

    Aluminum-clad, aluminum-based spent nuclear fuel (Al-SNF) from foreign and domestic research reactors (FRR/DRR) is being shipped to the Savannah River Site and placed in interim storage in a water basin. To enter the United States, a cask with loaded fuel must be certified to comply with the requirements in the Title 10 of the U.S. Code of Federal Regulations, Part 71. The requirements include demonstration of containment of the cask with its contents under normal and accident conditions. Many Al-SNF assemblies have suffered corrosion degradation in storage in poor quality water, and many of the fuel assemblies are 'failed' or have through-clad damage. A methodology was developed to evaluate containment of Al-SNF even with severe cladding breaches for transport in standard casks. The containment analysis methodology for Al-SNF is in accordance with the methodology provided in ANSI N14.5 and adopted by the U. S. Nuclear Regulatory Commission in NUREG/CR-6487 to meet the requirements of 10CFR71. The technical bases for the inputs and assumptions are specific to the attributes and characteristics of Al-SNF received from basin and dry storage systems and its subsequent performance under normal and postulated accident shipping conditions. The results of the calculations for a specific case of a cask loaded with breached fuel show that the fuel can be transported in standard shipping casks and maintained within the allowable release rates under normal and accident conditions. A sensitivity analysis has been conducted to evaluate the effects of modifying assumptions and to assess options for fuel at conditions that are not bounded by the present analysis. These options would include one or more of the following: reduce the fuel loading; increase fuel cooling time; reduce the degree of conservatism in the bounding assumptions; or measure the actual leak rate of the cask system. That is, containment analysis for alternative inputs at fuel-specific conditions and

  7. ABI1 and PP2CA Phosphatases Are Negative Regulators of Snf1-Related Protein Kinase1 Signaling in Arabidopsis

    OpenAIRE

    Rodrigues, A.; Adamo, M.; Crozet, P.; Margalha, L.; Confraria, A.; Martinho, C.; Elias, A.; Rabissi, A.; Lumbreras, V.; Gonzalez-Guzman, M.; Antoni, R.; Rodriguez, P. L.; Baena-Gonzalez, E.

    2013-01-01

    Plant survival under environmental stress requires the integration of multiple signaling pathways into a coordinated response, but the molecular mechanisms underlying this integration are poorly understood. Stress-derived energy deprivation activates the Snf1-related protein kinases1 (SnRK1s), triggering a vast transcriptional and metabolic reprogramming that restores homeostasis and promotes tolerance to adverse conditions. Here, we show that two clade A type 2C protein phosphatases (PP2Cs),...

  8. An innovative way of thinking nuclear waste management - Neutron physics of a reactor directly operating on SNF.

    Science.gov (United States)

    Merk, Bruno; Litskevich, Dzianis; Bankhead, Mark; Taylor, Richard J

    2017-01-01

    A solution for the nuclear waste problem is the key challenge for an extensive use of nuclear reactors as a major carbon free, sustainable, and applied highly reliable energy source. Partitioning and Transmutation (P&T) promises a solution for improved waste management. Current strategies rely on systems designed in the 60's for the massive production of plutonium. We propose an innovative strategic development plan based on invention and innovation described with the concept of developments in s-curves identifying the current boundary conditions, and the evolvable objectives. This leads to the ultimate, universal vision for energy production characterized by minimal use of resources and production of waste, while being economically affordable and safe, secure and reliable in operation. This vision is transformed into a mission for a disruptive development of the future nuclear energy system operated by burning of existing spent nuclear fuel (SNF) without prior reprocessing. This highly innovative approach fulfils the sustainability goals and creates new options for P&T. A proof on the feasibility from neutronic point of view is given demonstrating sufficient breeding of fissile material from the inserted SNF. The system does neither require new resources nor produce additional waste, thus it provides a highly sustainable option for a future nuclear system fulfilling the requests of P&T as side effect. In addition, this nuclear system provides enhanced resistance against misuse of Pu and a significantly reduced fuel cycle. However, the new system requires a demand driven rethinking of the separation process to be efficient.

  9. An innovative way of thinking nuclear waste management - Neutron physics of a reactor directly operating on SNF.

    Directory of Open Access Journals (Sweden)

    Bruno Merk

    Full Text Available A solution for the nuclear waste problem is the key challenge for an extensive use of nuclear reactors as a major carbon free, sustainable, and applied highly reliable energy source. Partitioning and Transmutation (P&T promises a solution for improved waste management. Current strategies rely on systems designed in the 60's for the massive production of plutonium. We propose an innovative strategic development plan based on invention and innovation described with the concept of developments in s-curves identifying the current boundary conditions, and the evolvable objectives. This leads to the ultimate, universal vision for energy production characterized by minimal use of resources and production of waste, while being economically affordable and safe, secure and reliable in operation. This vision is transformed into a mission for a disruptive development of the future nuclear energy system operated by burning of existing spent nuclear fuel (SNF without prior reprocessing. This highly innovative approach fulfils the sustainability goals and creates new options for P&T. A proof on the feasibility from neutronic point of view is given demonstrating sufficient breeding of fissile material from the inserted SNF. The system does neither require new resources nor produce additional waste, thus it provides a highly sustainable option for a future nuclear system fulfilling the requests of P&T as side effect. In addition, this nuclear system provides enhanced resistance against misuse of Pu and a significantly reduced fuel cycle. However, the new system requires a demand driven rethinking of the separation process to be efficient.

  10. The role of BAF (mSWI/SNF) complexes in mammalian neural development.

    Science.gov (United States)

    Son, Esther Y; Crabtree, Gerald R

    2014-09-01

    The BAF (mammalian SWI/SNF) complexes are a family of multi-subunit ATP-dependent chromatin remodelers that use ATP hydrolysis to alter chromatin structure. Distinct BAF complex compositions are possible through combinatorial assembly of homologous subunit families and can serve non-redundant functions. In mammalian neural development, developmental stage-specific BAF assemblies are found in embryonic stem cells, neural progenitors and postmitotic neurons. In particular, the neural progenitor-specific BAF complexes are essential for controlling the kinetics and mode of neural progenitor cell division, while neuronal BAF function is necessary for the maturation of postmitotic neuronal phenotypes as well as long-term memory formation. The microRNA-mediated mechanism for transitioning from npBAF to nBAF complexes is instructive for the neuronal fate and can even convert fibroblasts into neurons. The high frequency of BAF subunit mutations in neurological disorders underscores the rate-determining role of BAF complexes in neural development, homeostasis, and plasticity. © 2014 Wiley Periodicals, Inc.

  11. Steam Oxidation Testing in the Severe Accident Test Station

    Energy Technology Data Exchange (ETDEWEB)

    Pint, Bruce A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-08-01

    After the March 2011 accident at Fukushima Daiichi, Oak Ridge National Laboratory (ORNL) began conducting high temperature steam oxidation testing of candidate materials for accident tolerant fuel (ATF) cladding in August 2011 [1-11]. The ATF concept is to enhance safety margins in light water reactors (LWR) during severe accident scenarios by identifying materials with 100× slower steam oxidation rates compared to current Zr-based alloys. In 2012, the ORNL laboratory equipment was expanded and made available to the entire ATF community as the Severe Accident Test Station (SATS) [4,12]. Compared to the current UO2/Zr-based alloy fuel system, an ATF alternative would significantly reduce the rate of heat and hydrogen generation in the core during a coolant-limited severe accident [13-14]. The steam oxidation behavior of candidate materials is a key metric in the evaluation of ATF concepts and also an important input into models [15-17]. However, initial modeling work of FeCrAl cladding has used incomplete information on the physical properties of FeCrAl. Also, the steam oxidation data being collected at 1200°-1700°C is unique as no prior work has considered steam oxidation of alloys at such high temperatures. Also, because many accident scenarios include steadily increasing temperatures, the required data are not traditional isothermal exposures but exposures with varying “ramp” rates. In some cases, the steam oxidation behavior has been surprising and difficult to interpret. Thus, more fundamental information continues to be collected. In addition, more work continues to focus on commercially-manufactured tube material. This report summarizes recent work to characterize the behavior of candidate alloys exposed to high temperature steam, evaluate steam oxidation behavior in various ramp scenarios and continue to collect integral data on FeCrAl compared to conventional Zr-based cladding.

  12. Critique of the RASMUSSEN report (WASH-1400) on accident risks in U.S. commercial nuclear power plants

    International Nuclear Information System (INIS)

    Krueger, F.W.

    1976-06-01

    The RASMUSSEN study represents an excellent survey of the current possibilities to assess quantitatively the operational risk of nuclear power plants. To close the big gaps which turned out to be still existent in calculating the possible accidents sequences and their consequences but also in the statistical materials, only rough models could be used because of the limited capability of theoretical analyses to replace lacking experience. Contrary to previous studies the risk estimates have not deliberately been maximized, apart from the fact that in many cases no 'safe' side does a priori exist. Rather, the RASMUSSEN study tried to make 'reasonable realistic' assumptions concerning accident sequences and activity release consequences, but it is difficult to refute that the results will tend to underestimate systematically the accident consequences. Besides, in every case the range of uncertainty will very likely be greater than stated in the study, not least also because the results are substantially influenced by technical features of the nuclear power plants under discussion. This should be given attention in discussions using the quantitative results of the study as well as the fact that planning, construction and operation of nuclear power plants must be done with utmost accuracy to achieve the specified low orders of risk. (author)

  13. Key Characteristics of Combined Accident including TLOFW accident for PSA Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bo Gyung; Kang, Hyun Gook [KAIST, Daejeon (Korea, Republic of); Yoon, Ho Joon [Khalifa University of Science, Technology and Research, Abu Dhabi (United Arab Emirates)

    2015-05-15

    The conventional PSA techniques cannot adequately evaluate all events. The conventional PSA models usually focus on single internal events such as DBAs, the external hazards such as fire, seismic. However, the Fukushima accident of Japan in 2011 reveals that very rare event is necessary to be considered in the PSA model to prevent the radioactive release to environment caused by poor treatment based on lack of the information, and to improve the emergency operation procedure. Especially, the results from PSA can be used to decision making for regulators. Moreover, designers can consider the weakness of plant safety based on the quantified results and understand accident sequence based on human actions and system availability. This study is for PSA modeling of combined accidents including total loss of feedwater (TLOFW) accident. The TLOFW accident is a representative accident involving the failure of cooling through secondary side. If the amount of heat transfer is not enough due to the failure of secondary side, the heat will be accumulated to the primary side by continuous core decay heat. Transients with loss of feedwater include total loss of feedwater accident, loss of condenser vacuum accident, and closure of all MSIVs. When residual heat removal by the secondary side is terminated, the safety injection into the RCS with direct primary depressurization would provide alternative heat removal. This operation is called feed and bleed (F and B) operation. Combined accidents including TLOFW accident are very rare event and partially considered in conventional PSA model. Since the necessity of F and B operation is related to plant conditions, the PSA modeling for combined accidents including TLOFW accident is necessary to identify the design and operational vulnerabilities.The PSA is significant to assess the risk of NPPs, and to identify the design and operational vulnerabilities. Even though the combined accident is very rare event, the consequence of combined

  14. Severe accidents at nuclear power plants. Their risk assessment and accident management

    International Nuclear Information System (INIS)

    Abe, Kiyoharu.

    1995-05-01

    This document is to explain the severe accident issues. Severe Accidents are defined as accidents which are far beyond the design basis and result in severe damage of the core. Accidents at Three Mild Island in USA and at Chernobyl in former Soviet Union are examples of severe accidents. The causes and progressions of the accidents as well as the actions taken are described. Probabilistic Safety Assessment (PSA) is a method to estimate the risk of severe accidents at nuclear reactors. The methodology for PSA is briefly described and current status on its application to safety related issues is introduced. The acceptability of the risks which inherently accompany every technology is then discussed. Finally, provision of accident management in Japan is introduced, including the description of accident management measures proposed for BWRs and PWRs. (author)

  15. Severe accident phenomena

    International Nuclear Information System (INIS)

    Jokiniemi, J.; Kilpi, K.; Lindholm, I.; Maekynen, J.; Pekkarinen, E.; Sairanen, R.; Silde, A.

    1995-02-01

    Severe accidents are nuclear reactor accidents in which the reactor core is substantially damaged. The report describes severe reactor accident phenomena and their significance for the safety of nuclear power plants. A comprehensive set of phenomena ranging from accident initiation to containment behaviour and containment integrity questions are covered. The report is based on expertise gained in the severe accident assessment projects conducted at the Technical Research Centre of Finland (VTT). (49 refs., 32 figs., 12 tabs.)

  16. Enhanced Accident Tolerant LWR Fuels National Metrics Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    Lori Braase

    2013-01-01

    Commercialization. The activities performed during the feasibility assessment phase include laboratory scale experiments; fuel performance code updates; and analytical assessment of economic, operational, safety, fuel cycle, and environmental impacts of the new concepts. The development and qualification stage will consist of fuel fabrication and large scale irradiation and safety basis testing, leading to qualification and ultimate NRC licensing of the new fuel. The commercialization phase initiates technology transfer to industry for implementation. Attributes for fuels with enhanced accident tolerance include improved reaction kinetics with steam and slower hydrogen generation rate, while maintaining acceptable cladding thermo-mechanical properties; fuel thermo-mechanical properties; fuel-clad interactions; and fission-product behavior. These attributes provide a qualitative guidance for parameters that must be considered in the development of fuels and cladding with enhanced accident tolerance. However, quantitative metrics must be developed for these attributes. To initiate the quantitative metrics development, a Light Water Reactor Enhanced Accident Tolerant Fuels Metrics Development Workshop was held October 10-11, 2012, in Germantown, Maryland. This document summarizes the structure and outcome of the two-day workshop. Questions regarding the content can be directed to Lori Braase, 208-526-7763, lori.braase@inl.gov.

  17. Criticality accident of nuclear fuel facility. Think back on JCO criticality accident

    International Nuclear Information System (INIS)

    Naito, Keiji

    2003-09-01

    This book is written in order to understand the fundamental knowledge of criticality safety or criticality accident of nuclear fuel facility by the citizens. It consists of four chapters such as critical conditions and criticality accident of nuclear facility, risk of criticality accident, prevention of criticality accident and a measure at an occurrence of criticality accident. A definition of criticality, control of critical conditions, an aspect of accident, a rate of incident, damage, three sufferers, safety control method of criticality, engineering and administrative control, safety design of criticality, investigation of failure of safety control of JCO criticality accident, safety culture are explained. JCO criticality accident was caused with intention of disregarding regulation. It is important that we recognize the correct risk of criticality accident of nuclear fuel facility and prevent disasters. On the basis of them, we should establish safety culture. (S.Y.)

  18. Professional experience and traffic accidents/near-miss accidents among truck drivers.

    Science.gov (United States)

    Girotto, Edmarlon; Andrade, Selma Maffei de; González, Alberto Durán; Mesas, Arthur Eumann

    2016-10-01

    To investigate the relationship between the time working as a truck driver and the report of involvement in traffic accidents or near-miss accidents. A cross-sectional study was performed with truck drivers transporting products from the Brazilian grain harvest to the Port of Paranaguá, Paraná, Brazil. The drivers were interviewed regarding sociodemographic characteristics, working conditions, behavior in traffic and involvement in accidents or near-miss accidents in the previous 12 months. Subsequently, the participants answered a self-applied questionnaire on substance use. The time of professional experience as drivers was categorized in tertiles. Statistical analyses were performed through the construction of models adjusted by multinomial regression to assess the relationship between the length of experience as a truck driver and the involvement in accidents or near-miss accidents. This study included 665 male drivers with an average age of 42.2 (±11.1) years. Among them, 7.2% and 41.7% of the drivers reported involvement in accidents and near-miss accidents, respectively. In fully adjusted analysis, the 3rd tertile of professional experience (>22years) was shown to be inversely associated with involvement in accidents (odds ratio [OR] 0.29; 95% confidence interval [CI] 0.16-0.52) and near-miss accidents (OR 0.17; 95% CI 0.05-0.53). The 2nd tertile of professional experience (11-22 years) was inversely associated with involvement in accidents (OR 0.63; 95% CI 0.40-0.98). An evident relationship was observed between longer professional experience and a reduction in reporting involvement in accidents and near-miss accidents, regardless of age, substance use, working conditions and behavior in traffic. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Lessons learned from the West Valley spent nuclear fuel shipment within the United States

    International Nuclear Information System (INIS)

    Tyacke, M.J.; Anderson, T.

    2004-01-01

    This paper describes the lessons learned from the U.S. Department of Energy (DOE) transportation of 125 DOE-owned commercial spent nuclear fuel (SNF) assemblies by railroad from the West Valley Demonstration Project to the Idaho National Engineering and Environmental Laboratory (INEEL). On July 17, 2003, DOE made the largest single shipment of commercial SNF in the history of the United States. This was a highly visible and political shipment that used two specially designed Type B transportation and storage casks. This paper describes the background and history of the shipment. It discusses the technical challenges for licensing Type B packages for hauling large quantities of SNF, including the unique design features, testing and analysis. This paper also discusses the preshipment planning, preparations, coordination, route evaluation and selection, carrier selection and negotiations, security, inspections, tracking, and interim storage at the INEEL

  20. EPR design features to mitigate severe accident challenges

    International Nuclear Information System (INIS)

    Mazurkiewicz, S.M.; Fischer, M.; Bittermann, D.

    2005-01-01

    The EPR, an evolutionary pressurized water reactor (PWR), is a 4300-4500 MWth that incorporates proven technology within an optimized configuration to enhance safety. EPR was originally developed through a joint effort between Framatome ANP and Siemens by incorporating the best technological features from the French and German nuclear reactor fleets into a cost-competitive product. Commercial EPR units are currently being built in Finland at the Olkiluoto site, and planned for France at the Flamanville site. In recent months, Framatome ANP announced their intention to market the EPR units to China in response to a request for vendor bids as well as their intent to pursue design certification in the United States under 10CFR52. The EPR safety philosophy is based on a deterministic consideration of defense-in-depth complemented by probabilistic analyses. Not only is the EPR designed to prevent and mitigate design basis accidents (DBAs), it employs an extra level of safety associated with severe accident response. Therefore, as a design objective, features are included to ensure that radiological consequences are limited such that the need for stringent counter measures, such as evacuation and relocation of the nearby population, can be reasonably excluded. This paper discusses some of the innovative features of the EPR to address severe accident challenges. (author)

  1. Prevention of pedestrian accidents.

    OpenAIRE

    Kendrick, D

    1993-01-01

    Child pedestrian accidents are the most common road traffic accident resulting in injury. Much of the existing work on road traffic accidents is based on analysing clusters of accidents despite evidence that child pedestrian accidents tend to be more dispersed than this. This paper analyses pedestrian accidents in 573 children aged 0-11 years by a locally derived deprivation score for the years 1988-90. The analysis shows a significantly higher accident rate in deprived areas and a dose respo...

  2. Development of likelihood estimation method for criticality accidents of mixed oxide fuel fabrication facilities

    International Nuclear Information System (INIS)

    Tamaki, Hitoshi; Yoshida, Kazuo; Kimoto, Tatsuya; Hamaguchi, Yoshikane

    2010-01-01

    A criticality accident in a MOX fuel fabrication facility may occur depending on several parameters, such as mass inventory and plutonium enrichment. MOX handling units in the facility are designed and operated based on the double contingency principle to prevent criticality accidents. Control failures of at least two parameters are needed for the occurrence of criticality accident. To evaluate the probability of such control failures, the criticality conditions of each parameter for a specific handling unit are necessary for accident scenario analysis to be clarified quantitatively with a criticality analysis computer code. In addition to this issue, a computer-based control system for mass inventory is planned to be installed into MOX handling equipment in a commercial MOX fuel fabrication plant. The reliability analysis is another important issue in evaluating the likelihood of control failure caused by software malfunction. A likelihood estimation method for criticality accident has been developed with these issues been taken into consideration. In this paper, an example of analysis with the proposed method and the applicability of the method are also shown through a trial application to a model MOX fabrication facility. (author)

  3. Accident Locations, MDTA Accidents, Accidents on MDTA locations, Accidents on I 95, US 50, I 695, Accident on John F Kennedy Highway, Nice Bridge, Bay Bridge locations, Published in 2011, 1:1200 (1in=100ft) scale, Maryland Transportation Authority.

    Data.gov (United States)

    NSGIC State | GIS Inventory — Accident Locations dataset current as of 2011. MDTA Accidents, Accidents on MDTA locations, Accidents on I 95, US 50, I 695, Accident on John F Kennedy Highway, Nice...

  4. The FOX transcription factor Hcm1 regulates oxidative metabolism in response to early nutrient limitation in yeast. Role of Snf1 and Tor1/Sch9 kinases.

    Science.gov (United States)

    Rodríguez-Colman, María José; Sorolla, M Alba; Vall-Llaura, Núria; Tamarit, Jordi; Ros, Joaquim; Cabiscol, Elisa

    2013-08-01

    Within Saccharomyces cerevisiae, Hcm1is a member of the forkhead transcription factor family with a role in chromosome organization. Our group recently described its involvement in mitochondrial biogenesis and stress resistance, and reports here that Hcm1 played a role in adaptation to respiratory metabolism when glucose or nitrogen was decreased. Regulation of Hcm1 activity occurs in at least three ways: i) protein quantity, ii) subcellular localization, and iii) transcriptional activity. Transcriptional activity was measured using a reporter gene fused to a promoter that contains a binding site for Hcm1. We also analyzed the levels of several genes whose expression is known to be regulated by Hcm1 levels and the role of the main kinases known to respond to nutrients. Lack of sucrose-nonfermenting (Snf1) kinase increases cytoplasmic localization of Hcm1, whereas Δtor1 cells showed a mild increase in nuclear Hcm1. In vitro experiments showed that Snf1 clearly phosphorylates Hcm1 while Sch9 exerts a milder phosphorylation. Although in vitroTor1 does not directly phosphorylate Hcm1, in vivo rapamycin treatment increases nuclear Hcm1. We conclude that Hcm1 participates in the adaptation of cells from fermentation to respiratory metabolism during nutrient scarcity. According to our hypothesis, when nutrient levels decrease, Snf1 phosphorylates Hcm1. This results in a shift from the cytoplasm to the nucleus and increased transcriptional activity of genes involved in respiration, use of alternative energy sources, NAD synthesis and oxidative stress resistance. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. An innovative way of thinking nuclear waste management – Neutron physics of a reactor directly operating on SNF

    Science.gov (United States)

    Litskevich, Dzianis; Bankhead, Mark; Taylor, Richard J.

    2017-01-01

    A solution for the nuclear waste problem is the key challenge for an extensive use of nuclear reactors as a major carbon free, sustainable, and applied highly reliable energy source. Partitioning and Transmutation (P&T) promises a solution for improved waste management. Current strategies rely on systems designed in the 60’s for the massive production of plutonium. We propose an innovative strategic development plan based on invention and innovation described with the concept of developments in s-curves identifying the current boundary conditions, and the evolvable objectives. This leads to the ultimate, universal vision for energy production characterized by minimal use of resources and production of waste, while being economically affordable and safe, secure and reliable in operation. This vision is transformed into a mission for a disruptive development of the future nuclear energy system operated by burning of existing spent nuclear fuel (SNF) without prior reprocessing. This highly innovative approach fulfils the sustainability goals and creates new options for P&T. A proof on the feasibility from neutronic point of view is given demonstrating sufficient breeding of fissile material from the inserted SNF. The system does neither require new resources nor produce additional waste, thus it provides a highly sustainable option for a future nuclear system fulfilling the requests of P&T as side effect. In addition, this nuclear system provides enhanced resistance against misuse of Pu and a significantly reduced fuel cycle. However, the new system requires a demand driven rethinking of the separation process to be efficient. PMID:28749952

  6. Reactor safety study. An assessment of accident risks in U. S. commercial nuclear power plants. Executive summary: main report. [PWR and BWR

    Energy Technology Data Exchange (ETDEWEB)

    1975-10-01

    Information is presented concerning the objectives and organization of the reactor safety study; the basic concepts of risk; the nature of nuclear power plant accidents; risk assessment methodology; reactor accident risk; and comparison of nuclear risks to other societal risks.

  7. Mcm1p binding sites in ARG1 positively regulate Gcn4p binding and SWI/SNF recruitment

    OpenAIRE

    Yoon, Sungpil; Hinnebusch, Alan G.

    2009-01-01

    Transcription of the arginine biosynthetic gene ARG1 is activated by Gcn4p, a transcription factor induced by starvation for any amino acid. Previously we showed that Gcn4p binding stimulates the recruitment of Mcm1p and co-activator SWI/SNF to ARG1 in cells via Gcn4p induction through amino acid starvation. Here we report that Gcn4p binding is reduced by point mutations of the Mcm1p binding site and increased by overexpression of Mcm1p. This result suggests that Mcm1p plays a positive role i...

  8. Use of PSA and severe accident assessment results for the accident management

    International Nuclear Information System (INIS)

    Jang, S. H.; Kim, H. G.; Jang, H. S.; Moon, S. K.; Park, J. U.

    1993-12-01

    The objectives for this study are to investigate the basic principle or methodology which is applicable to accident management, by using the results of PSA and severe accident research, and also facilitate the preparation of accidents management program in the future. This study was performed as follows: derivation of measures for core damage prevention, derivation of measures for accident mitigation, application of computerized tool to assess severe accident management

  9. Use of PSA and severe accident assessment results for the accident management

    Energy Technology Data Exchange (ETDEWEB)

    Jang, S H; Kim, H G; Jang, H S; Moon, S K; Park, J U [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    1993-12-15

    The objectives for this study are to investigate the basic principle or methodology which is applicable to accident management, by using the results of PSA and severe accident research, and also facilitate the preparation of accidents management program in the future. This study was performed as follows: derivation of measures for core damage prevention, derivation of measures for accident mitigation, application of computerized tool to assess severe accident management.

  10. Road safety practices among commercial motorcyclists in a rural town in Nigeria: implications for health education.

    Science.gov (United States)

    Amoran, O E; Eme, Owoaje; Giwa, O A; Gbolahan, O B

    This cross-sectional, community-based study was carried out among commercial motorcyclists in Igboora. All the commercial motor parks in Igboora were visited and all the commercial motorcyclists who consented to participate in the study were interviewed. Information on the respondents' socio-demographic characteristics, and the practice of road safety measures was collected using an interviewer administered questionnaire. A total of 299 motorcyclists were interviewed. All (100%) of them were males. The mean age of the respondents was 27.4 +/- 7.4 years. One hundred eighty-two (60.7%) of the motorcyclists had the correct knowledge of the purpose of Highway Code. Only 70 (23.3%) could recognize more than half of the currently used road safety codes and 47 (15.7%) obey these road safety codes more than half of the time they see it. Only 183 (61.2%) of them had a driving license and 72 (24.1%) were able to produce these licenses on demand. All (100%) of the respondents did not use any protective helmet. Those who have longer years of working experience, higher level of education and higher knowledge of the safety codes practice it more regularly (r = 0.198, p = 0.001, chi2= 9.31, p = 0.025, and r = 0.28, p = 0.001 respectively). One hundred thirty-six (45.5%) have been involved in at least one accident in the preceding year. The overall incidence of road traffic accident was 2.16 per 1,000. There was however on statistically significant association between the practice of road safety codes and the occurrence of road traffic accidents (chi2= 0.176, p = 0.916). The study shows that the practice of road safety measures was low in this rural Nigerian community and was not associated with the incidence of road traffic accidents. Introducing road safety education particularly targeted at educating the motorcyclists on the importance and practice of road safety measures would lead to an increase in the practice of the safety measures and hopefully a reduction in the incidence

  11. Risk assessment in long-term storage of spent nuclear fuel

    International Nuclear Information System (INIS)

    Ahn, T.; Guttmann, J.; Mohseni, A.

    2013-01-01

    This paper presents probabilistic risk-informed approaches that the Nuclear Regulatory Commission (NRC) staff is planning to consider in preparing regulatory bases for long-term storage of spent nuclear fuel (SNF) for up to 300 years. Due to uncertainties associated with long-term SNF storage, the NRC is considering a probabilistic risk-informed approach as well as a deterministic design-based approach. The uncertainties considered here are primarily associated with materials aging of the canister and SNF in the cask system during long-term storage of SNF. This paper discusses some potential risk contributors involved in long-term SNF storage. Methods of performance evaluation are presented that assess the various types of risks involved. They include deterministic evaluation, probabilistic evaluation, and consequence assessment under normal conditions and the conditions of accidents and natural hazards. Some potentially important technical issues resulting from the consideration of a probabilistic risk-informed evaluation of the cask system performance are discussed for the canister and SNF integrity. These issues are also discussed in comparison with the deterministic approach for comparison purposes, as appropriate. Probabilistic risk-informed methods can provide insights that deterministic methods may not capture. Two specific examples include stress corrosion cracking of the canister and hydrogen-induced cladding failure. These examples are discussed in more detail, in terms of their effects on radionuclide release and nuclear subcriticality associated with the failure. The plan to consider the probabilistic risk-informed approaches is anticipated to provide helpful regulatory insights for long-term storage of SNF that provide reasonable assurance for public health and safety. (authors)

  12. Role of BWR secondary containments in severe accident mitigation: issues and insights from recent analyses

    International Nuclear Information System (INIS)

    Greene, S.R.

    1988-01-01

    All commercial boiling water reactor (BWR) plants in the US employ primary containments of the pressure suppression design. These primary containments are surrounded and enclosed by a secondary containment consisting of a reactor building and refueling bay (MK I and MK II designs), a shield building, auxiliary building and fuel building (MK III), or an auxiliary building and enclosure building (Grand Gulf style MK III). Although secondary containment designs are highly plant specific, their purpose is to minimize the ground level release of radioactive material for a spectrum of traditional design basis accidents. While not designed for severe accident mitigation, these secondary containments might also reduce the radiological consequences of severe accidents. This issue is receiving increasing attention due to concerns that BWR MK I primary containment integrity would be lost should a significant mass of molten debris escape the reactor vessel during a severe accident. This paper presents a brief overview of domestic BWR secondary containment designs and highlights plant-specific features that could influence secondary containment severe accident survivability and accident mitigation effectiveness. Current issues surrounding secondary containment performance are discussed, and insights gained from recent ORNL secondary containment studies of Browns Ferry, Peach Bottom, and Shoreham are presented. Areas of significant uncertainty are identified and recommendations for future research are presented

  13. [Accidents and injuries at work].

    Science.gov (United States)

    Standke, W

    2014-06-01

    In the case of an accident at work, the person concerned is insured by law according to the guidelines of the Sozialgesetzbuch VII as far as the injuries have been caused by this accident. The most important source of information on the incident in question is the accident report that has to be sent to the responsible institution for statutory accident insurance and prevention by the employer, if the accident of the injured person is fatal or leads to an incapacity to work for more than 3 days (= reportable accident). Data concerning accidents like these are sent to the Deutsche Gesetzliche Unfallversicherung (DGUV) as part of a random sample survey by the institutions for statutory accident insurance and prevention and are analyzed statistically. Thus the key issues of accidents can be established and used for effective prevention. Although the success of effective accident prevention is undisputed, there were still 919,025 occupational accidents in 2011, with clear gender-related differences. Most occupational accidents involve the upper and lower extremities. Accidents are analyzed comprehensively and the results are published and made available to all interested parties in an effort to improve public awareness of possible accidents. Apart from reportable accidents, data on the new occupational accident pensions are also gathered and analyzed statistically. Thus, additional information is gained on accidents with extremely serious consequences and partly permanent injuries for the accident victims.

  14. Severe accident analysis methodology in support of accident management

    International Nuclear Information System (INIS)

    Boesmans, B.; Auglaire, M.; Snoeck, J.

    1997-01-01

    The author addresses the implementation at BELGATOM of a generic severe accident analysis methodology, which is intended to support strategic decisions and to provide quantitative information in support of severe accident management. The analysis methodology is based on a combination of severe accident code calculations, generic phenomenological information (experimental evidence from various test facilities regarding issues beyond present code capabilities) and detailed plant-specific technical information

  15. Study of the feasibility of distributed cathodic arc as a plasma source for development of the technology for plasma separation of SNF and radioactive wastes

    Energy Technology Data Exchange (ETDEWEB)

    Amirov, R. Kh.; Vorona, N. A.; Gavrikov, A. V.; Liziakin, G. D.; Polistchook, V. P.; Samoylov, I. S.; Smirnov, V. P.; Usmanov, R. A., E-mail: ravus46@yandex.ru; Yartsev, I. M. [Russian Academy of Sciences, Joint Institute for High Temperatures (Russian Federation)

    2015-12-15

    One of the key problems in the development of plasma separation technology is designing a plasma source which uses condensed spent nuclear fuel (SNF) or nuclear wastes as a raw material. This paper covers the experimental study of the evaporation and ionization of model materials (gadolinium, niobium oxide, and titanium oxide). For these purposes, a vacuum arc with a heated cathode on the studied material was initiated and its parameters in different regimes were studied. During the experiment, the cathode temperature, arc current, arc voltage, and plasma radiation spectra were measured, and also probe measurements were carried out. It was found that the increase in the cathode heating power leads to the decrease in the arc voltage (to 3 V). This fact makes it possible to reduce the electron energy and achieve singly ionized plasma with a high degree of ionization to fulfill one of the requirements for plasma separation of SNF. This finding is supported by the analysis of the plasma radiation spectrum and the results of the probe diagnostics.

  16. Biomass accident investigations – missed opportunities for learning and accident prevention

    DEFF Research Database (Denmark)

    Hedlund, Frank Huess

    2017-01-01

    The past decade has seen a major increase in the production of energy from biomass. The growth has been mirrored in an increase of serious biomass related accidents involving fires, gas explosions, combustible dust explosions and the release of toxic gasses. There are indications that the number...... of bioenergy related accidents is growing faster than the energy production. This paper argues that biomass accidents, if properly investigated and lessons shared widely, provide ample opportunities for improving general hazard awareness and safety performance of the biomass industry. The paper examines...... selected serious accidents involving biogas and wood pellets in Denmark and argues that such opportunities for learning were missed because accident investigations were superficial, follow-up incomplete and information sharing absent. In one particularly distressing case, a facility saw a repeat accident...

  17. Detection and analysis of accident black spots with even small accident figures.

    NARCIS (Netherlands)

    Oppe, S.

    1982-01-01

    Accident black spots are usually defined as road locations with high accident potentials. In order to detect such hazardous locations we have to know the probability of an accident for a traffic situation of some kind, or the mean number of accidents for some unit of time. In almost all procedures

  18. Reactor safety study. An assessment of accident risks in U. S. commercial nuclear power plants. Appendix VI. Calculation of reactor accident consequences. [PWR and BWR

    Energy Technology Data Exchange (ETDEWEB)

    1975-10-01

    Information is presented concerning the radioactive releases from the containment following accidents; radioactive inventory of the reactor core; atmospheric dispersion; reactor sites and meteorological data; radioactive decay and deposition from plumes; finite distance of plume travel; dosimetric models; health effects; demographic data; mitigation of radiation exposure; economic model; and calculated results with consequence model.

  19. Regulation Plans on Severe Accidents developed by KINS Severe Accident Regulation Preparation TFT

    International Nuclear Information System (INIS)

    Kim, Kyun Tae; Chung, Ku Young; Na, Han Bee

    2016-01-01

    Some nuclear power plants in Fukushima Daiichi site had lost their emergency reactor cooling function for long-time so the fuels inside the reactors were molten, and the integrity of containment was damaged. Therefore, large amount of radioactive material was released to environment. Because the social and economic effects of severe accidents are enormous, Korean Government already issued 'Severe Accident Policy' in 2001 which requires nuclear power plant operators to set up 'Quantitative Safety Goal', to do 'Probabilistic Safety Analysis', to install 'Severe Accident Countermeasures' and to make 'Severe Accident Management Plan'. After the Fukushima disaster, a Special Safety Inspection was performed for all operating nuclear power plants of Korea. The inspection team from industry, academia, and research institutes assessed Korean NPPs capabilities to cope with or respond to severe accidents and emergency situation caused by natural disasters such as a large earthquake or tsunami. As a result of the special inspection, about 50 action items were identified to increase the capability to cope with natural disaster and severe accidents. Nuclear Safety Act has been amended to require NPP operators to submit Accident Management Plant as part of operating license application. The KINS Severe Accident Regulation Preparation TFT had first investigated oversea severe accident regulation trend before and after the Fukushima accident. Then, the TFT has developed regulation draft for severe accidents such as Severe accident Management Plans, the required design features for new NPPs to prevent severe accident against multiple failures and beyond-design external events, countermeasures to mitigate severe accident and to keep the integrity of containment, and assessment methodology on safety assessment plan and probabilistic safety assessment

  20. Underreporting of maritime accidents to vessel accident databases.

    Science.gov (United States)

    Hassel, Martin; Asbjørnslett, Bjørn Egil; Hole, Lars Petter

    2011-11-01

    Underreporting of maritime accidents is a problem not only for authorities trying to improve maritime safety through legislation, but also to risk management companies and other entities using maritime casualty statistics in risk and accident analysis. This study collected and compared casualty data from 01.01.2005 to 31.12.2009, from IHS Fairplay and the maritime authorities from a set of nations. The data was compared to find common records, and estimation of the true number of occurred accidents was performed using conditional probability given positive dependency between data sources, several variations of the capture-recapture method, calculation of best case scenario assuming perfect reporting, and scaling up a subset of casualty information from a marine insurance statistics database. The estimated upper limit reporting performance for the selected flag states ranged from 14% to 74%, while the corresponding estimated coverage of IHS Fairplay ranges from 4% to 62%. On average the study results document that the number of unreported accidents makes up roughly 50% of all occurred accidents. Even in a best case scenario, only a few flag states come close to perfect reporting (94%). The considerable scope of underreporting uncovered in the study, indicates that users of statistical vessel accident data should assume a certain degree of underreporting, and adjust their analyses accordingly. Whether to use correction factors, a safety margin, or rely on expert judgment, should be decided on a case by case basis. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Regulation Plans on Severe Accidents developed by KINS Severe Accident Regulation Preparation TFT

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyun Tae; Chung, Ku Young; Na, Han Bee [KINS, Daejeon (Korea, Republic of)

    2016-05-15

    Some nuclear power plants in Fukushima Daiichi site had lost their emergency reactor cooling function for long-time so the fuels inside the reactors were molten, and the integrity of containment was damaged. Therefore, large amount of radioactive material was released to environment. Because the social and economic effects of severe accidents are enormous, Korean Government already issued 'Severe Accident Policy' in 2001 which requires nuclear power plant operators to set up 'Quantitative Safety Goal', to do 'Probabilistic Safety Analysis', to install 'Severe Accident Countermeasures' and to make 'Severe Accident Management Plan'. After the Fukushima disaster, a Special Safety Inspection was performed for all operating nuclear power plants of Korea. The inspection team from industry, academia, and research institutes assessed Korean NPPs capabilities to cope with or respond to severe accidents and emergency situation caused by natural disasters such as a large earthquake or tsunami. As a result of the special inspection, about 50 action items were identified to increase the capability to cope with natural disaster and severe accidents. Nuclear Safety Act has been amended to require NPP operators to submit Accident Management Plant as part of operating license application. The KINS Severe Accident Regulation Preparation TFT had first investigated oversea severe accident regulation trend before and after the Fukushima accident. Then, the TFT has developed regulation draft for severe accidents such as Severe accident Management Plans, the required design features for new NPPs to prevent severe accident against multiple failures and beyond-design external events, countermeasures to mitigate severe accident and to keep the integrity of containment, and assessment methodology on safety assessment plan and probabilistic safety assessment.

  2. Specific features of RBMK severe accidents progression and approach to the accident management

    International Nuclear Information System (INIS)

    Vasilevskij, V.P.; Nikitin, Yu.M.; Petrov, A.A.; Potapov, A.A.; Cherkashov, Yu.M.

    2001-01-01

    Fundamental construction features of the LWGR facilities (absence of common external containment shell, disintegrated circulation circuit and multichannel reactor core, positive vapor reactivity coefficient, high mass of thermally capacious graphite moderator) predetermining development of assumed heavy non-projected accidents and handling them are treated. Rating the categories of the reactor core damages for non-projected accidents and accident types producing specific grope of damages is given. Passing standard non-projected accidents, possible methods of attack accident consequences, as well as methods of calculated analysis of non-projected accidents are demonstrated [ru

  3. Large Break LOCA Accident Management Strategies for Accidents With Large Containment Leaks

    International Nuclear Information System (INIS)

    Sdouz, Gert

    2006-01-01

    The goal of this work is the investigation of the influence of different accident management strategies on the thermal-hydraulics in the containment during a Large Break Loss of Coolant Accident with a large containment leak from the beginning of the accident. The increasing relevance of terrorism suggests a closer look at this kind of severe accidents. Normally the course of severe accidents and their associated phenomena are investigated with the assumption of an intact containment from the beginning of the accident. This intact containment has the ability to retain a large part of the radioactive inventory. In these cases there is only a release via a very small leakage due to the un-tightness of the containment up to cavity bottom melt through. This paper represents the last part of a comprehensive study on the influence of accident management strategies on the source term of VVER-1000 reactors. Basically two different accident sequences were investigated: the 'Station Blackout'- sequence and the 'Large Break LOCA'. In a first step the source term calculations were performed assuming an intact containment from the beginning of the accident and no accident management action. In a further step the influence of different accident management strategies was studied. The last part of the project was a repetition of the calculations with the assumption of a damaged containment from the beginning of the accident. This paper concentrates on the last step in the case of a Large Break LOCA. To be able to compare the results with calculations performed years ago the calculations were performed using the Source Term Code Package (STCP), hydrogen explosions are not considered. In this study four different scenarios have been investigated. The main parameter was the switch on time of the spray systems. One of the results is the influence of different accident management strategies on the source term. In the comparison with the sequence with intact containment it was

  4. SEVERE ACCIDENT ISSUES RAISED BY THE FUKUSHIMA ACCIDENT AND IMPROVEMENTS SUGGESTED

    OpenAIRE

    SONG, JIN HO; KIM, TAE WOON

    2014-01-01

    This paper revisits the Fukushima accident to draw lessons in the aspect of nuclear safety considering the fact that the Fukushima accident resulted in core damage for three nuclear power plants simultaneously and that there is a high possibility of a failure of the integrity of reactor vessel and primary containment vessel. A brief review on the accident progression at Fukushima nuclear power plants is discussed to highlight the nature and characteristic of the event. As the severe accide...

  5. CRITICALITY CALCULATION FOR THE MOST REACTIVE DEGRADED CONFIGURATIONS OF THE FFTF SNF CODISPOSAL WP CONTAINING AN INTACT IDENT-69 CONTAINER

    International Nuclear Information System (INIS)

    D.R. Moscalu

    2002-01-01

    The objective of this calculation is to perform additional degraded mode criticality evaluations of the Department of Energy's (DOE) Fast Flux Test Facility (FFTF) Spent Nuclear Fuel (SNF) codisposed in a 5-Defense High-Level Waste (5-DHLW) Waste Package (WP). The scope of this calculation is limited to the most reactive degraded configurations of the codisposal WP with an almost intact Ident-69 container (breached and flooded but otherwise non-degraded) containing intact FFTF SNF pins. The configurations have been identified in a previous analysis (CRWMS M andO 1999a) and the present evaluations include additional relevant information that was left out of the original calculations. The additional information describes the exact distribution of fissile material in each container (DOE 2002a). The effects of the changes that have been included in the baseline design of the codisposal WP (CRWMS M andO 2000) are also investigated. The calculation determines the effective neutron multiplication factor (k eff ) for selected degraded mode internal configurations of the codisposal waste package. These calculations will support the demonstration of the technical viability of the design solution adopted for disposing of MOX (FFTF) spent nuclear fuel in the potential repository. This calculation is subject to the Quality Assurance Requirements and Description (QARD) (DOE 2002b) per the activity evaluation under work package number P6212310M2 in the technical work plan TWP-MGR-MD-0000101 (BSC 2002)

  6. Nuclear accidents

    International Nuclear Information System (INIS)

    1987-01-01

    On 27 May 1986 the Norwegian government appointed an inter-ministerial committee of senior officials to prepare a report on experiences in connection with the Chernobyl accident. The present second part of the committee's report describes proposals for measures to prevent and deal with similar accidents in the future. The committee's evaluations and proposals are grouped into four main sections: Safety and risk at nuclear power plants; the Norwegian contingency organization for dealing with nuclear accidents; compensation issues; and international cooperation

  7. Nuclear accident dosimetry

    International Nuclear Information System (INIS)

    1982-01-01

    The film presents statistical data on criticality accidents. It outlines past IAEA activities on criticality accident dosimetry and the technical documents that resulted from this work. The film furthermore illustrates an international comparison study on nuclear accident dosimetry conducted at the Atomic Energy Research Establishment, Harwell, United Kingdom

  8. Nuclear accident dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1983-12-31

    The film presents statistical data on criticality accidents. It outlines past IAEA activities on criticality accident dosimetry and the technical documents that resulted from this work. The film furthermore illustrates an international comparison study on nuclear accident dosimetry conducted at the Atomic Energy Research Establishment, Harwell, United Kingdom

  9. Planning for large-scale accidents: learning from the Three Mile Island accident

    International Nuclear Information System (INIS)

    Fischer, D.W.

    1981-01-01

    Decision-making issues raised at the Three Mile Island nuclear accident in Pennsylvania are explored. The organizations involved, their interconnections, and decisions are described. The underlying issues bearing on allocation of effort to pre-accident planning and actual accident responses are also noted. Finally, a framework from this effort is used for guiding the planning of operations for future accidents. (author)

  10. Radiation accidents

    International Nuclear Information System (INIS)

    Nenot, J.C.

    1996-01-01

    Analysis of radiation accidents over a 50 year period shows that simple cases, where the initiating events were immediately recognised, the source identified and under control, the medical input confined to current handling, were exceptional. In many cases, the accidents were only diagnosed when some injuries presented by the victims suggested the radiological nature of the cause. After large-scale accidents, the situation becomes more complicated, either because of management or medical problems, or both. The review of selected accidents which resulted in severe consequences shows that most of them could have been avoided; lack of regulations, contempt for rules, human failure and insufficient training have been identified as frequent initiating parameters. In addition, the situation was worsened because of unpreparedness, insufficient planning, unadapted resources, and underestimation of psychosociological aspects. (author)

  11. Comparison of the effects of two legal blood alcohol limits: the presence of alcohol in traffic accidents according to category of driver in Izmir, Turkey.

    Science.gov (United States)

    Karakus, Akan; İdiz, Nuri; Dalgiç, Mustafa; Uluçay, Tarik; Sincar, Yasemin

    2015-01-01

    Under existing Turkish road traffic law, there are 2 different blood alcohol concentration (BAC) limits allowed for drivers in 2013: zero blood alcohol and ≤0.50 g/L. All public transport, taxi, commercial, and official vehicle drivers must maintain a zero blood alcohol concentration while driving. Private vehicle drivers must maintain a BAC of 0.50 g/L or lower. The aim of the recent study was to evaluate the effect of these 2 legal blood alcohol limits on nonfatal traffic accidents that occurred due to the driver being under the influence of alcohol. This retrospective study was performed to evaluate the blood alcohol concentration of 224 drivers in nonfatal road accidents between June 2010 and July 2011 using headspace gas chromatography at the Izmir Forensic Medicine Group Presidency, Turkey. All cases evaluated by the toxicology department were entered into a database. We used descriptive statistics, χ(2) test, and independent sampling test to analyze the data. The total number of drivers involved in nonfatal traffic accidents was 224; 191 were private vehicle drivers and 33 were public transport, taxi, commercial, and official vehicle drivers. In the present study, alcohol was detected in the blood of about 27.2% (n = 61) of the 224 drivers. Sixty (31.4%) private vehicle drivers involved in nonfatal traffic accidents tested positive for alcohol. BAC values were also above the legal limit (0.50 g/L) in 27.7% (n = 53) of private vehicle drivers. However, the BAC was above the legal limit in only 3% (n = 1) of public transport, commercial, and official vehicle drivers involved in nonfatal traffic accidents. These results showed that private vehicle drivers subject to a BAC limit of ≤0.50 g/L were significantly associated with an increased risk of nonfatal accident involvement than drivers subject to a zero BAC limit (odds ratio [OR] = 12.29, 95% confidence interval [CI], 1.64-92.22; Fisher's exact test, P accidents in Turkey.

  12. Reactor safety study. An assessment of accident risks in U. S. commercial nuclear power plants. Appendices VII, VIII, IX, and X. [PWR and BWR

    Energy Technology Data Exchange (ETDEWEB)

    1975-10-01

    Information is presented concerning the release of radioactivity in reactor accidents; physical processes in reactor meltdown accidents; safety design rationale for nuclear power plants; and design adequacy.

  13. Evaluation of severe accident risk in the Pickering a risk assessment

    International Nuclear Information System (INIS)

    Dinnie, K.S.; Raina, V.M.

    1997-01-01

    The nature of the design of commercial power plants is such that significant impacts on public health can only occur if a number of barriers fail. Rigorous design and licensing requirements ensure that the more likely accidents do not fail all these barriers and their contribution to risk is likely to be small. The task of estimating accident risk must, therefore, focus more towards those less likely but potentially more serious combinations of failures that are characterized by the following: a) a large release of fission products into the containment atmosphere, b) a breach in the containment envelope, and c) the existence of a driving force to expel the containment atmosphere to the outside environment. The likelihood of such conditions existing simultaneously during the course of an accident is expected to be small, such that experience and data regarding the behaviour of plant systems under such conditions is sparse or non-existent. The challenge of Probabilistic Safety Assessments (PSAs) is to examine the potential for severe accidents using approaches that are sufficiently detailed and realistic to provide valid information regarding plant risk and susceptibilities, while simple enough to keep the analysis manageable. This paper outlines the key features of the Pickering A Risk Assessment (PARA) (1) and the manner in which it addresses these issues, and provides some insights into the results and conclusions drawn from the study. (author)

  14. Analysis of Individual and Environmental Factors for Road Traffic Accidents in Sirjan-Bandarabbas Road between 2010 and 2011, Iran

    Directory of Open Access Journals (Sweden)

    Ghorbanali Mohammadi

    2016-10-01

    Full Text Available Sirjan -Bandarabbas road is one of the important commercial roads in Iran and for Sirjan’s area situation and relevance between Sirjan and other states in Iran so high percentage of goods that forwarded from Bandarabbas to other states transit from Sirjan .Therefore this road is as one important transition road and traffic road too .This study analyzed road traffic accidents were occurred between 2010 and 201in Sirjan- Bandarabbas road. Individual and demographic factors include Time of accidents, Drivers age, time of the days, seat belt and safety laws, Guilty vehicle, Mode of accident and education Level. Time of day analyses suggested that the highest percentage of road traffic injuries occurred in the time group between 12-18 hours. Drivers with the age group of 36-50 had more involvement in death accidents. The findings of this study also revealed that most of the collisions was front to back and front to side. Female drivers were found to be generally safer drivers than their male counterparts; male drivers had a higher involvement rate in road traffic accidents. This study indicated that Observe safety laws, Guilty vehicle and Mode of accidents have a meaningful relationship with Type of accidents in road traffic accidents in Sirjan Bandarabbas road.

  15. Managing severe reactor accidents. A review and evaluation of our knowledge on reactor accidents and accident management

    International Nuclear Information System (INIS)

    Gustavsson, Veine

    2002-11-01

    The report gives a review of the results from the last years research on severe reactor accidents, and an opinion on the possibilities to refine the present strategies for accident management in Swedish and Finnish BWRs. The following aspect of reactor accidents are the major themes of the study: 1. Early pressure relief from hydrogen production; 2. Recriticality in re-flooded, degraded core; 3. Melt-through; 4. Steam explosion after melt-through; 5. Coolability of the melt after after melt-through; 6. Hydrogen fire in the reactor containment; 7. Leaking containment; 8. Hydrogen fire in the reactor building; 9. Long-time developments after a severe accident; 10. Accidents during shutdown for overhaul; 11. Information need for remedial actions. Possibilities for improving the strategies in each of these areas are discussed. The review shows that our knowledge is sufficient in the areas 1, 2, 4, 6, 8. For the other areas, more research is needed

  16. Standard guide for evaluation of materials used in extended service of interim spent nuclear fuel dry storage systems

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 Part of the total inventory of commercial spent nuclear fuel (SNF) is stored in dry cask storage systems (DCSS) under licenses granted by the U.S. Nuclear Regulatory Commission (NRC). The purpose of this guide is to provide information to assist in supporting the renewal of these licenses, safely and without removal of the SNF from its licensed confinement, for periods beyond those governed by the term of the original license. This guide provides information on materials behavior under conditions that may be important to safety evaluations for the extended service of the renewal period. This guide is written for DCSS containing light water reactor (LWR) fuel that is clad in zirconium alloy material and stored in accordance with the Code of Federal Regulations (CFR), at an independent spent-fuel storage installation (ISFSI). The components of an ISFSI, addressed in this document, include the commercial SNF, canister, cask, and all parts of the storage installation including the ISFSI pad. The language of t...

  17. EFFICIENCY OF REPEATED AND UNSCHEDULED TRAINING AS THE MEASURES TO PREVENT ACCIDENTS AT SUPPLY DEPOTS AND WAREHOUSES

    Directory of Open Access Journals (Sweden)

    Bocharova Irina Nikolaevna

    2013-05-01

    Full Text Available This paper presents the results of the analysis of the state of occupational safety at supply depots and warehouses. It is revealed that most accidents involve the employees who have less than one year’s service. Experience has proven that the preventive activities to avoid occupational traumatism are efficient when a complex of workplace safety measures is implemented. The experts consider the repeated and unscheduled training to be very important events. This is supported by the fact that among the employees of the commercial establishments who underwent repeated and unscheduled training, the number of individuals who suffered an accident is small. The efficient functioning of the occupational safety training system is infeasible without ensuring the motivation for assimilating the knowledge and forming the complete foundation for safe labor. In order to reduce the number of accidents, one should proceed from the principle of responding to accidents to the system for professional risk management.

  18. The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility

    KAUST Repository

    Jé gu, Teddy; Veluchamy, Alaguraj; Ramirez Prado, Juan Sebastian; Rizzi-Paillet, Charley; Perez, Magalie; Lhomme, Anaï s; Latrasse, David; Coleno, Emeline; Vicaire, Serge; Legras, Sté phanie; Jost, Bernard; Rougé e, Martin; Barneche, Fredy; Bergounioux, Catherine; Crespi, Martin; Mahfouz, Magdy M.; Hirt, Heribert; Raynaud, Cé cile; Benhamed, Moussa

    2017-01-01

    Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored.In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms.These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions.

  19. The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility

    KAUST Repository

    Jégu, Teddy

    2017-06-15

    Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored.In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms.These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions.

  20. Preventing accidents

    Science.gov (United States)

    2005-08-01

    As the most effective strategy for improving safety is to prevent accidents from occurring at all, the Volpe Center applies a broad range of research techniques and capabilities to determine causes and consequences of accidents and to identify, asses...

  1. Blue Ribbon Commission, Yucca Mountain Closure, Court Actions - Future of Decommissioned Reactors, Operating Reactors and Nuclear Power - 13249

    International Nuclear Information System (INIS)

    Devgun, Jas S.

    2013-01-01

    Issues related to back-end of the nuclear fuel cycle continue to be difficult for the commercial nuclear power industry and for the decision makers at the national and international level. In the US, the 1982 NWPA required DOE to develop geological repositories for SNF and HLW but in spite of extensive site characterization efforts and over ten billion dollars spent, a repository opening is nowhere in sight. There has been constant litigation against the DOE by the nuclear utilities for breach of the 'standard contract' they signed with the DOE under the NWPA. The SNF inventory continues to rise both in the US and globally and the nuclear industry has turned to dry storage facilities at reactor locations. In US, the Blue Ribbon Commission on America's Nuclear Future issued its report in January 2012 and among other items, it recommends a new, consent-based approach to siting of facilities, prompt efforts to develop one or more geologic disposal facilities, and prompt efforts to develop one or more consolidated storage facilities. In addition, the March 2011 Fukushima Daiichi accident had a severe impact on the future growth of nuclear power. The nuclear industry is focusing on mitigation strategies for beyond design basis events and in the US, the industry is in the process of implementing the recommendations from NRC's Near Term Task Force. (authors)

  2. Statistical aspects of carbon fiber risk assessment modeling. [fire accidents involving aircraft

    Science.gov (United States)

    Gross, D.; Miller, D. R.; Soland, R. M.

    1980-01-01

    The probabilistic and statistical aspects of the carbon fiber risk assessment modeling of fire accidents involving commercial aircraft are examined. Three major sources of uncertainty in the modeling effort are identified. These are: (1) imprecise knowledge in establishing the model; (2) parameter estimation; and (3)Monte Carlo sampling error. All three sources of uncertainty are treated and statistical procedures are utilized and/or developed to control them wherever possible.

  3. MELCOR assessment of sequential severe accident mitigation actions under SGTR accident

    International Nuclear Information System (INIS)

    Choi, Wonjun; Jeon, Joongoo; Kim, Nam Kyung; Kim, Sung Joong

    2017-01-01

    The representative example of the severe accident studies using the severe accident code is investigation of effectiveness of developed severe accident management (SAM) strategy considering the positive and adverse effects. In Korea, some numerical studies were performed to investigate the SAM strategy using various severe accident codes. Seo et.al performed validation of RCS depressurization strategy and investigated the effect of severe accident management guidance (SAMG) entry condition under small break loss of coolant accident (SBLOCA) without safety injection (SI), station blackout (SBO), and total loss of feed water (TLOFW) scenarios. The SGTR accident with the sequential mitigation actions according to the flow chart of SAMG was simulated by the MELCOR 1.8.6 code. Three scenariospreventing the RPV failure were investigated in terms of fission product release, hydrogen risk, and the containment pressure. Major conclusions can be summarized as follows: (1) According to the flow chart of SAMG, RPV failure can be prevented depending on the method of RCS depressurization. (2) To reduce the release of fission product during the injecting into SGs, a temporary opening of SDS before the injecting into SGs was suggested. These modified sequences of mitigation actions can reduce the release of fission product and the adverse effect of SDS.

  4. Visualization of Traffic Accidents

    Science.gov (United States)

    Wang, Jie; Shen, Yuzhong; Khattak, Asad

    2010-01-01

    Traffic accidents have tremendous impact on society. Annually approximately 6.4 million vehicle accidents are reported by police in the US and nearly half of them result in catastrophic injuries. Visualizations of traffic accidents using geographic information systems (GIS) greatly facilitate handling and analysis of traffic accidents in many aspects. Environmental Systems Research Institute (ESRI), Inc. is the world leader in GIS research and development. ArcGIS, a software package developed by ESRI, has the capabilities to display events associated with a road network, such as accident locations, and pavement quality. But when event locations related to a road network are processed, the existing algorithm used by ArcGIS does not utilize all the information related to the routes of the road network and produces erroneous visualization results of event locations. This software bug causes serious problems for applications in which accurate location information is critical for emergency responses, such as traffic accidents. This paper aims to address this problem and proposes an improved method that utilizes all relevant information of traffic accidents, namely, route number, direction, and mile post, and extracts correct event locations for accurate traffic accident visualization and analysis. The proposed method generates a new shape file for traffic accidents and displays them on top of the existing road network in ArcGIS. Visualization of traffic accidents along Hampton Roads Bridge Tunnel is included to demonstrate the effectiveness of the proposed method.

  5. Supervisor's accident investigation handbook

    International Nuclear Information System (INIS)

    1980-02-01

    This pamphlet was prepared by the Environmental Health and Safety Department (EH and S) of Lawrence Berkeley Laboratory (LBL) to provide LBL supervisors with a handy reference to LBL's accident investigation program. The publication supplements the Accident and Emergencies section of LBL's Regulations and Procedures Manual, Pub. 201. The present guide discusses only accidents that are to be investigated by the supervisor. These accidents are classified as Type C by the Department of Energy (DOE) and include most occupational injuries and illnesses, government motor-vehicle accidents, and property damages of less than $50,000

  6. Cost per severe accident as an index for severe accident consequence assessment and its applications

    International Nuclear Information System (INIS)

    Silva, Kampanart; Ishiwatari, Yuki; Takahara, Shogo

    2014-01-01

    The Fukushima Accident emphasizes the need to integrate the assessments of health effects, economic impacts, social impacts and environmental impacts, in order to perform a comprehensive consequence assessment of severe accidents in nuclear power plants. “Cost per severe accident” is introduced as an index for that purpose. The calculation methodology, including the consequence analysis using level 3 probabilistic risk assessment code OSCAAR and the calculation method of the cost per severe accident, is proposed. This methodology was applied to a virtual 1,100 MWe boiling water reactor. The breakdown of the cost per severe accident was provided. The radiation effect cost, the relocation cost and the decontamination cost were the three largest components. Sensitivity analyses were carried out, and parameters sensitive to cost per severe accident were specified. The cost per severe accident was compared with the amount of source terms, to demonstrate the performance of the cost per severe accident as an index to evaluate severe accident consequences. The ways to use the cost per severe accident for optimization of radiation protection countermeasures and for estimation of the effects of accident management strategies are discussed as its applications. - Highlights: • Cost per severe accident is used for severe accident consequence assessment. • Assessments of health, economic, social and environmental impacts are included. • Radiation effect, relocation and decontamination costs are important cost components. • Cost per severe accident can be used to optimize radiation protection measures. • Effects of accident management can be estimated using the cost per severe accident

  7. Object-Oriented Bayesian Networks (OOBN) for Aviation Accident Modeling and Technology Portfolio Impact Assessment

    Science.gov (United States)

    Shih, Ann T.; Ancel, Ersin; Jones, Sharon M.

    2012-01-01

    The concern for reducing aviation safety risk is rising as the National Airspace System in the United States transforms to the Next Generation Air Transportation System (NextGen). The NASA Aviation Safety Program is committed to developing an effective aviation safety technology portfolio to meet the challenges of this transformation and to mitigate relevant safety risks. The paper focuses on the reasoning of selecting Object-Oriented Bayesian Networks (OOBN) as the technique and commercial software for the accident modeling and portfolio assessment. To illustrate the benefits of OOBN in a large and complex aviation accident model, the in-flight Loss-of-Control Accident Framework (LOCAF) constructed as an influence diagram is presented. An OOBN approach not only simplifies construction and maintenance of complex causal networks for the modelers, but also offers a well-organized hierarchical network that is easier for decision makers to exploit the model examining the effectiveness of risk mitigation strategies through technology insertions.

  8. Trends in state-level freight accident rates: An enhancement of risk factor development for RADTRAN

    International Nuclear Information System (INIS)

    Saricks, C.; Kvitek, T.

    1991-01-01

    Under the Nuclear Waste Policy Act, the Department of Energy's Office of Civilian Radioactive Waste Management (OCRWM) is concerned with understanding and managing risk as it applies to the shipment of spent commercial nuclear reactor fuel. Understanding risk in relation to mode and geography may provide opportunities to minimize radiological and non-radiological risks of transportation. To enhance such an understanding, a set of state-or waterway-specific accident, fatality, and injury rates (expressed as rates per shipment kilometer) by transportation mode and highway administrative class was developed, using publicly-available data bases. Adjustments made to accommodate miscoded or incomplete information in accident data are described, as well as the procedures for estimating state-level flow data. Results indicate that the shipping conditions under which spent fuel is likely to be transported should be less subject to accidents than the ''average'' shipment within mode. 10 refs., 3 tabs

  9. FY17 Status Report: Research on Stress Corrosion Cracking of SNF Interim Storage Canisters.

    Energy Technology Data Exchange (ETDEWEB)

    Schindelholz, Eric John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bryan, Charles R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Alexander, Christopher L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-09-01

    This progress report describes work done in FY17 at Sandia National Laboratories (SNL) to assess the localized corrosion performance of container/cask materials used in the interim storage of spent nuclear fuel (SNF). Of particular concern is stress corrosion cracking (SCC), by which a through-wall crack could potentially form in a canister outer wall over time intervals that are shorter than possible dry storage times. Work in FY17 refined our understanding of the chemical and physical environment on canister surfaces, and evaluated the relationship between chemical and physical environment and the form and extent of corrosion that occurs. The SNL corrosion work focused predominantly on pitting corrosion, a necessary precursor for SCC, and process of pit-to-crack transition; it has been carried out in collaboration with university partners. SNL is collaborating with several university partners to investigate SCC crack growth experimentally, providing guidance for design and interpretation of experiments.

  10. Application of the accident management information needs methodology to a severe accident sequence

    International Nuclear Information System (INIS)

    Ward, L.W.; Hanson, D.J.; Nelson, W.R.; Solberg, D.E.

    1989-01-01

    The U.S. Nuclear Regulatory Commission is conducting an accident management research program that emphasizes the use of severe accident research to enhance the ability of plant operating personnel to effectively manage severe accidents. Hence, it is necessary to ensure that the plant instrumentation and information systems adequately provide this information to the operating staff during accident conditions. A methodology to identify and assess the information needs of the operating staff of a nuclear power plant during a severe accident has been developed. The methodology identifies (a) the information needs of the plant personnel during a wide range of accident conditions, (b) the existing plant measurements capable of supplying these information needs and minor additions to instrument and display systems that would enhance management capabilities, (c) measurement capabilities and limitations during severe accident conditions, and (d) areas in which the information systems could mislead plant personnel

  11. Application of the accident management information needs methodology to a severe accident sequence

    Energy Technology Data Exchange (ETDEWEB)

    Ward, L.W.; Hanson, D.J.; Nelson, W.R. (Idaho National Engineering Laboratory, Idaho Falls (USA)); Solberg, D.E. (Nuclear Regulatory Commission, Washington, DC (USA))

    1989-11-01

    The U.S. Nuclear Regulatory Commission is conducting an accident management research program that emphasizes the use of severe accident research to enhance the ability of plant operating personnel to effectively manage severe accidents. Hence, it is necessary to ensure that the plant instrumentation and information systems adequately provide this information to the operating staff during accident conditions. A methodology to identify and assess the information needs of the operating staff of a nuclear power plant during a severe accident has been developed. The methodology identifies (a) the information needs of the plant personnel during a wide range of accident conditions, (b) the existing plant measurements capable of supplying these information needs and minor additions to instrument and display systems that would enhance management capabilities, (c) measurement capabilities and limitations during severe accident conditions, and (d) areas in which the information systems could mislead plant personnel.

  12. Significant Radionuclides Determination

    Energy Technology Data Exchange (ETDEWEB)

    Jo A. Ziegler

    2001-07-31

    The purpose of this calculation is to identify radionuclides that are significant to offsite doses from potential preclosure events for spent nuclear fuel (SNF) and high-level radioactive waste expected to be received at the potential Monitored Geologic Repository (MGR). In this calculation, high-level radioactive waste is included in references to DOE SNF. A previous document, ''DOE SNF DBE Offsite Dose Calculations'' (CRWMS M&O 1999b), calculated the source terms and offsite doses for Department of Energy (DOE) and Naval SNF for use in design basis event analyses. This calculation reproduces only DOE SNF work (i.e., no naval SNF work is included in this calculation) created in ''DOE SNF DBE Offsite Dose Calculations'' and expands the calculation to include DOE SNF expected to produce a high dose consequence (even though the quantity of the SNF is expected to be small) and SNF owned by commercial nuclear power producers. The calculation does not address any specific off-normal/DBE event scenarios for receiving, handling, or packaging of SNF. The results of this calculation are developed for comparative analysis to establish the important radionuclides and do not represent the final source terms to be used for license application. This calculation will be used as input to preclosure safety analyses and is performed in accordance with procedure AP-3.12Q, ''Calculations'', and is subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (DOE 2000) as determined by the activity evaluation contained in ''Technical Work Plan for: Preclosure Safety Analysis, TWP-MGR-SE-000010'' (CRWMS M&O 2000b) in accordance with procedure AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities''.

  13. Normal accidents

    International Nuclear Information System (INIS)

    Perrow, C.

    1989-01-01

    The author has chosen numerous concrete examples to illustrate the hazardousness inherent in high-risk technologies. Starting with the TMI reactor accident in 1979, he shows that it is not only the nuclear energy sector that bears the risk of 'normal accidents', but also quite a number of other technologies and industrial sectors, or research fields. The author refers to the petrochemical industry, shipping, air traffic, large dams, mining activities, and genetic engineering, showing that due to the complexity of the systems and their manifold, rapidly interacting processes, accidents happen that cannot be thoroughly calculated, and hence are unavoidable. (orig./HP) [de

  14. Accident analysis. A review of the various accidents classifications

    International Nuclear Information System (INIS)

    Martin Martin, L.; Figueras, J.M.

    1982-01-01

    The objective of the accident analysis, in relation with the safety evaluation, environmental impact and emergency planning, should be to identify the total risk to the population and workers from potential accidents in the facility, analizing it over full spectrum of severity. (auth.)

  15. French policy for managing the post-accident phase of a nuclear accident.

    Science.gov (United States)

    Gallay, F; Godet, J L; Niel, J C

    2015-06-01

    In 2005, at the request of the French Government, the Nuclear Safety Authority (ASN) established a Steering Committee for the Management of the Post-Accident Phase of a Nuclear Accident or a Radiological Emergency, with the objective of establishing a policy framework. Under the supervision of ASN, this Committee, involving several tens of experts from different backgrounds (e.g. relevant ministerial offices, expert agencies, local information commissions around nuclear installations, non-governmental organisations, elected officials, licensees, and international experts), developed a number of recommendations over a 7-year period. First published in November 2012, these recommendations cover the immediate post-emergency situation, and the transition and longer-term periods of the post-accident phase in the case of medium-scale nuclear accidents causing short-term radioactive release (less than 24 h) that might occur at French nuclear facilities. They also apply to actions to be undertaken in the event of accidents during the transportation of radioactive materials. These recommendations are an important first step in preparation for the management of a post-accident situation in France in the case of a nuclear accident. © The Chartered Institution of Building Services Engineers 2014.

  16. Accident progression event tree analysis for postulated severe accidents at N Reactor

    International Nuclear Information System (INIS)

    Wyss, G.D.; Camp, A.L.; Miller, L.A.; Dingman, S.E.; Kunsman, D.M.; Medford, G.T.

    1990-06-01

    A Level II/III probabilistic risk assessment (PRA) has been performed for N Reactor, a Department of Energy (DOE) production reactor located on the Hanford reservation in Washington. The accident progression analysis documented in this report determines how core damage accidents identified in the Level I PRA progress from fuel damage to confinement response and potential releases the environment. The objectives of the study are to generate accident progression data for the Level II/III PRA source term model and to identify changes that could improve plant response under accident conditions. The scope of the analysis is comprehensive, excluding only sabotage and operator errors of commission. State-of-the-art methodology is employed based largely on the methods developed by Sandia for the US Nuclear Regulatory Commission in support of the NUREG-1150 study. The accident progression model allows complex interactions and dependencies between systems to be explicitly considered. Latin Hypecube sampling was used to assess the phenomenological and systemic uncertainties associated with the primary and confinement system responses to the core damage accident. The results of the analysis show that the N Reactor confinement concept provides significant radiological protection for most of the accident progression pathways studied

  17. Commercial Aircraft Integrated Vehicle Health Management Study

    Science.gov (United States)

    Reveley, Mary S.; Briggs, Jeffrey L.; Evans, Joni K.; Jones, Sharon Monica; Kurtoglu, Tolga; Leone, Karen M.; Sandifer, Carl E.; Thomas, Megan A.

    2010-01-01

    Statistical data and literature from academia, industry, and other government agencies were reviewed and analyzed to establish requirements for fixture work in detection, diagnosis, prognosis, and mitigation for IVHM related hardware and software. Around 15 to 20 percent of commercial aircraft accidents between 1988 and 2003 involved inalftfnctions or failures of some aircraft system or component. Engine and landing gear failures/malfunctions dominate both accidents and incidents. The IVI vl Project research technologies were found to map to the Joint Planning and Development Office's National Research and Development Plan (RDP) as well as the Safety Working Group's National Aviation Safety Strategic. Plan (NASSP). Future directions in Aviation Technology as related to IVHlvl were identified by reviewing papers from three conferences across a five year time span. A total of twenty-one trend groups in propulsion, aeronautics and aircraft categories were compiled. Current and ftiture directions of IVHM related technologies were gathered and classified according to eight categories: measurement and inspection, sensors, sensor management, detection, component and subsystem monitoring, diagnosis, prognosis, and mitigation.

  18. STRUCTURAL CALCULATIONS FOR THE LIFTING IN VERTICAL ORIENTATION OF 5-DHLW/DOE SNF SINGLE CRM WASTE PACKAGES

    International Nuclear Information System (INIS)

    S. Mastilovic

    1999-01-01

    The purpose of this activity is to determine the structural response of the extension of outer shell (which is referred to as skirt throughout this document) designs of both long and short design concepts of 5-Defense High-Level Waste (DHLW) Department of Energy (DOE) spent nuclear fuel (SNF) single corrosion resistant material (CRM) waste packages (WP), subjected to a gravitational load in the course of lifting in vertical orientation. The scope of this document is limited to reporting the calculation results in terms of stress intensity magnitudes. This activity is associated with the WP design; calculations are performed by the Waste Package Design group. AP-3.124, Revision 0, ICN 0, Calculations, is used to perform the calculation and develop the document

  19. Probability of spent fuel transportation accidents

    International Nuclear Information System (INIS)

    McClure, J.D.

    1981-07-01

    The transported volume of spent fuel, incident/accident experience and accident environment probabilities were reviewed in order to provide an estimate of spent fuel accident probabilities. In particular, the accident review assessed the accident experience for large casks of the type that could transport spent (irradiated) nuclear fuel. This review determined that since 1971, the beginning of official US Department of Transportation record keeping for accidents/incidents, there has been one spent fuel transportation accident. This information, coupled with estimated annual shipping volumes for spent fuel, indicated an estimated annual probability of a spent fuel transport accident of 5 x 10 -7 spent fuel accidents per mile. This is consistent with ordinary truck accident rates. A comparison of accident environments and regulatory test environments suggests that the probability of truck accidents exceeding regulatory test for impact is approximately 10 -9 /mile

  20. Application of the accident management information needs methodology to a severe accident sequence

    International Nuclear Information System (INIS)

    Ward, L.W.; Hanson, D.J.; Nelson, W.R.; Solberg, D.E.

    1989-01-01

    The U.S. Nuclear Regulatory Commission (NRC) is conducting an Accident Management Research Program that emphasizes the application of severe accident research results to enhance the capability of plant operating personnel to effectively manage severe accidents. A methodology to identify and assess the information needs of the operating staff of a nuclear power plant during a severe accident has been developed as part of the research program designed to resolve this issue. The methodology identifies the information needs of the plant personnel during a wide range of accident conditions, the existing plant measurements capable of supplying these information needs and what, if any minor additions to instrument and display systems would enhance the capability to manage accidents, known limitations on the capability of these measurements to function properly under the conditions that will be present during a wide range of severe accidents, and areas in which the information systems could mislead plant personnel. This paper presents an application of this methodology to a severe accident sequence to demonstrate its use in identifying the information which is available for management of the event. The methodology has been applied to a severe accident sequence in a Pressurized Water Reactor with a large dry containment. An examination of the capability of the existing measurements was then performed to determine whether the information needs can be supplied

  1. Review of light water reactor safety through the Three Mile Island accident

    International Nuclear Information System (INIS)

    Phung, D.L.

    1984-05-01

    This review of light water reactor safety through the Three Mile Island accident has the purpose of establishing the baseline over which safety achievement post-TMI is assessed, and the need for new reactor designs and business direction is judged. Five major areas of reactor safety pre-TMI are examined: (1) safety philosophy and institutions, (2) reactor design criteria, (3) operational problems, (4) the Rasmussen reactor safety study, and (5) the TMI accident and repercussions. Although nuclear power has made spectacular achievements over the period pre-TMI and although TMI is technically a minor accident, this review concludes that there were basic flaws in the technology and in the manner safety philosophy was conceived and carried out. These flaws included (1) a reactor design that has high core power density, low heat capacity, and low system tolerance to upsets, (2) reactor deployment that had been expedited without extensive operational experience, (3) rules and regulations that had to play catch-up with commercial reactor development, (4) an industry that was fragmented, short-sighted, and tended to rely on the Nuclear Regulatory Commission for safety guidance, (5) information that was not effectively shared, and (6) attention that was inadequate to the human aspects of reactor operation and to public reaction to the specter of a reactor accident, major or minor

  2. Reactor Safety Gap Evaluation of Accident Tolerant Components and Severe Accident Analysis

    International Nuclear Information System (INIS)

    Farmer, Mitchell T.; Bunt, R.; Corradini, M.; Ellison, Paul B.; Francis, M.; Gabor, John D.; Gauntt, R.; Henry, C.; Linthicum, R.; Luangdilok, W.; Lutz, R.; Paik, C.; Plys, M.; Rabiti, Cristian; Rempe, J.; Robb, K.; Wachowiak, R.

    2015-01-01

    The overall objective of this study was to conduct a technology gap evaluation on accident tolerant components and severe accident analysis methodologies with the goal of identifying any data and/or knowledge gaps that may exist, given the current state of light water reactor (LWR) severe accident research, and additionally augmented by insights obtained from the Fukushima accident. The ultimate benefit of this activity is that the results can be used to refine the Department of Energy's (DOE) Reactor Safety Technology (RST) research and development (R&D) program plan to address key knowledge gaps in severe accident phenomena and analyses that affect reactor safety and that are not currently being addressed by the industry or the Nuclear Regulatory Commission (NRC).

  3. Reactor Safety Gap Evaluation of Accident Tolerant Components and Severe Accident Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Farmer, Mitchell T. [Argonne National Lab. (ANL), Argonne, IL (United States); Bunt, R. [Southern Nuclear, Atlanta, GA (United States); Corradini, M. [Univ. of Wisconsin, Madison, WI (United States); Ellison, Paul B. [GE Power and Water, Duluth, GA (United States); Francis, M. [Argonne National Lab. (ANL), Argonne, IL (United States); Gabor, John D. [Erin Engineering, Walnut Creek, CA (United States); Gauntt, R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Henry, C. [Fauske and Associates, Burr Ridge, IL (United States); Linthicum, R. [Exelon Corp., Chicago, IL (United States); Luangdilok, W. [Fauske and Associates, Burr Ridge, IL (United States); Lutz, R. [PWR Owners Group (PWROG); Paik, C. [Fauske and Associates, Burr Ridge, IL (United States); Plys, M. [Fauske and Associates, Burr Ridge, IL (United States); Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rempe, J. [Rempe and Associates LLC, Idaho Falls, ID (United States); Robb, K. [Argonne National Lab. (ANL), Argonne, IL (United States); Wachowiak, R. [Electric Power Research Inst. (EPRI), Knovville, TN (United States)

    2015-01-31

    The overall objective of this study was to conduct a technology gap evaluation on accident tolerant components and severe accident analysis methodologies with the goal of identifying any data and/or knowledge gaps that may exist, given the current state of light water reactor (LWR) severe accident research, and additionally augmented by insights obtained from the Fukushima accident. The ultimate benefit of this activity is that the results can be used to refine the Department of Energy’s (DOE) Reactor Safety Technology (RST) research and development (R&D) program plan to address key knowledge gaps in severe accident phenomena and analyses that affect reactor safety and that are not currently being addressed by the industry or the Nuclear Regulatory Commission (NRC).

  4. Persistence of airline accidents.

    Science.gov (United States)

    Barros, Carlos Pestana; Faria, Joao Ricardo; Gil-Alana, Luis Alberiko

    2010-10-01

    This paper expands on air travel accident research by examining the relationship between air travel accidents and airline traffic or volume in the period from 1927-2006. The theoretical model is based on a representative airline company that aims to maximise its profits, and it utilises a fractional integration approach in order to determine whether there is a persistent pattern over time with respect to air accidents and air traffic. Furthermore, the paper analyses how airline accidents are related to traffic using a fractional cointegration approach. It finds that airline accidents are persistent and that a (non-stationary) fractional cointegration relationship exists between total airline accidents and airline passengers, airline miles and airline revenues, with shocks that affect the long-run equilibrium disappearing in the very long term. Moreover, this relation is negative, which might be due to the fact that air travel is becoming safer and there is greater competition in the airline industry. Policy implications are derived for countering accident events, based on competition and regulation. © 2010 The Author(s). Journal compilation © Overseas Development Institute, 2010.

  5. Programmatic changes due to TMI-2 [Three Mile Island Unit 2]: Accident planning

    International Nuclear Information System (INIS)

    Wingert, V.L.

    1988-01-01

    The focus of the paper is lessons learned for emergency planning and preparedness form the Three Mile Island Unit 2 (TMI-2) accident. The lessons learned are examined from two perspectives: (a) lessons learned that have resulted in programmatic changes, and (b) lessons learned that have not been adequately addressed. There is no doubt that the TMI-2 accident is the pivotal event that caused a major rethinking of the pre-TMI emergency preparedness posture and led to a fundamentally different approach to emergency preparedness for commercial nuclear power plant accidents. While this new approach has evolved into a comprehensive, systematic, and even prototypical national program, it has also generated new problems: escalating costs for state and local governments and leveraging of the federal licensing process by state and local governments who do not want specific nuclear power plants to operate. A discussion of the primary lessons learned on emergency preparedness is presented under the following topics: beyond defense-in-depth, predetermined action, mandatory emergency planning and preparedness, and federal coordination

  6. Evaluation of severe accident environmental conditions taking accident management strategy into account for equipment survivability assessments

    International Nuclear Information System (INIS)

    Lee, Byung Chul; Jeong, Ji Hwan; Na, Man Gyun; Kim, Soong Pyung

    2003-01-01

    This paper presents a methodology utilizing accident management strategy in order to determine accident environmental conditions in equipment survivability assessments. In case that there is well-established accident management strategy for specific nuclear power plant, an application of this tool can provide a technical rationale on equipment survivability assessment so that plant-specific and time-dependent accident environmental conditions could be practically and realistically defined in accordance with the equipment and instrumentation required for accident management strategy or action appropriately taken. For this work, three different tools are introduced; Probabilistic Safety Assessment (PSA) outcomes, major accident management strategy actions, and Accident Environmental Stages (AESs). In order to quantitatively investigate an applicability of accident management strategy to equipment survivability, the accident simulation for a most likely scenario in Korean Standard Nuclear Power Plants (KSNPs) is performed with MAAP4 code. The Accident Management Guidance (AMG) actions such as the Reactor Control System (RCS) depressurization, water injection into the RCS, the containment pressure and temperature control, and hydrogen concentration control in containment are applied. The effects of these AMG actions on the accident environmental conditions are investigated by comparing with those from previous normal accident simulation, especially focused on equipment survivability assessment. As a result, the AMG-involved case shows the higher accident consequences along the accident environmental stages

  7. Human Factors Engineering and Ergonomics Analysis for the Canister Storage Building (CSB) Results and Findings

    International Nuclear Information System (INIS)

    GARVIN, L.J.

    1999-01-01

    The purpose for this supplemental report is to follow-up and update the information in SNF-3907, Human Factors Engineering (HFE) Analysis: Results and Findings. This supplemental report responds to applicable U.S. Department of Energy Safety Analysis Report review team comments and questions. This Human Factors Engineering and Ergonomics (HFE/Erg) analysis was conducted from April 1999 to July 1999; SNF-3907 was based on analyses accomplished in October 1998. The HFE/Erg findings presented in this report and SNF-3907, along with the results of HNF-3553, Spent Nuclear Fuel Project, Final Safety Analysis Report. Annex A, ''Canister Storage Building Final Safety Analysis Report,'' Chapter A3.0, ''Hazards and Accidents Analyses,'' provide the technical basis for preparing or updating HNF-3553, Annex A, Chapter A13.0, ''Human Factors Engineering.'' The findings presented in this report allow the HNF-3553 Chapter 13.0, ''Human Factors,'' to respond fully to the HFE requirements established in DOE Order 5480.23, Nuclear Safety Analysis Reports

  8. Human Factors Engineering and Ergonomics Analysis for the Canister Storage Building (CSB): Results and Findings

    International Nuclear Information System (INIS)

    GARVIN, L.J.

    1999-01-01

    The purpose for this supplemental report is to follow-up and update the information in SNF-3907, Human Factors Engineering (HFE) Analysis: Results and Findings. This supplemental report responds to applicable U.S. Department of Energy Safety Analysis Report review team comments and questions. This Human Factors Engineering and Ergonomics (HFE/Erg) analysis was conducted from April 1999 to July 1999; SNF-3907 was based on analyses accomplished in October 1998. The HFE/Erg findings presented in this report and SNF-3907, along with the results of HNF-3553, Spent Nuclear Fuel Project, Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report,'' Chapter A3.0, ''Hazards and Accidents Analyses,'' provide the technical basis for preparing or updating HNF-3553. Annex A, Chaptex A13.0, ''Human Factors Engineering.'' The findings presented in this report allow the HNF-3553 Chapter 13.0, ''Human Factors,'' to respond fully to the HFE requirements established in DOE Order 5480.23, Nuclear Safety Analysis Reports

  9. Review of nuclear reactor accidents

    International Nuclear Information System (INIS)

    Connelly, J.W.; Storr, G.J.

    1989-01-01

    Two types of severe reactor accidents - loss of coolant or coolant flow and transient overpower (TOP) accidents - are described and compared. Accidents in research reactors are discussed. The 1961 SL1 accident in the US is used as an illustration as it incorporates the three features usually combined in a severe accident - a design flaw or flaws in the system, a circumvention of safety circuits or procedures, and gross operator error. The SL1 reactor, the reactivity accident and the following fuel-coolant interaction and steam explosion are reviewed. 3 figs

  10. Historical aspects of radiation accidents

    International Nuclear Information System (INIS)

    Mettler, F.A. Jr.; Ricks, R.C.

    1990-01-01

    Radiation accidents are extremely rare events; however, the last two years have witnessed the largest radiation accidents in both the eastern and western hemispheres. It is the purpose of this chapter to review how radiation accidents are categorized, examine the temporal changes in frequency and severity, give illustrative examples of several types of radiation accidents, and finally, to describe the various registries for radiation accidents

  11. Applicability of simplified methods to evaluate consequences of criticality accident using past accident data

    International Nuclear Information System (INIS)

    Nakajima, Ken

    2003-01-01

    Applicability of four simplified methods to evaluate the consequences of criticality accident was investigated. Fissions in the initial burst and total fissions were evaluated using the simplified methods and those results were compared with the past accident data. The simplified methods give the number of fissions in the initial burst as a function of solution volume; however the accident data did not show such tendency. This would be caused by the lack of accident data for the initial burst with high accuracy. For total fissions, simplified almost reproduced the upper envelope of the accidents. However several accidents, which were beyond the applicable conditions, resulted in the larger total fissions than the evaluations. In particular, the Tokai-mura accident in 1999 gave in the largest total specific fissions, because the activation of cooling system brought the relatively high power for a long time. (author)

  12. Accident Tolerant Fuel Concepts for Light Water Reactors. Proceedings of a Technical Meeting

    International Nuclear Information System (INIS)

    2016-06-01

    Nuclear fuel is a highly complex material that has been subject to continuous development over the past 40 years and has reached a stage where it can be safely and reliably irradiated up to 65 GWd/tU in commercial nuclear reactors. During this time, there have been many improvements to the original designs and materials used. However, the basic design of uranium oxide fuel pellets clad with zirconium alloy tubing has remained the fuel choice for the vast majority of commercial nuclear power plants. Severe accidents, such as those at the Three Mile Island and Fukushima Daiichi have shown that under such extreme conditions, nuclear fuel will fail and the high temperature reactions between zirconoi alloys and water will lead to the generation of hydrogen, with the potential for explosions to occur, daming the plant further. Recognizing that the current fuel designs are vulnerable to severe accident conditions, tehre is renewed interesst in alternative fuel designs that would be more resistant to fuel failure and hydrogen production. Such new fuel designs will need to be compatible with existing fuel and reactor systems if they are to be utilized in the current reactor fleet and in current new build designs, but there is also the possibility of new designs for new reactor systems. This publication provides a record of the Technical Meeting on Accident Tolerant Fuel Concepts for Light Water Reactors, held at Oak Ridge National Laboratories (ORNL), United States of America, 13-16 October 2014, to consider the early stages of research and development into accident tolerant fuel. There were 45 participants from 10 countries taking part in the meeting, with 32 papers organized into 7 sessions, of which 27 are included in this publication. This meeting is part of a wider investigation into such designs, and it is anticipated that further Technical Meetings and research programmes will be undertaken in this field

  13. Post-accident radiation monitors

    International Nuclear Information System (INIS)

    Laughlin, G.J.; Kathren, R.L.

    1982-01-01

    Under contract to the Nuclear Safety Analysis Center of the Electric Power Research Institute, technical information and specifications were obtained for commercially available radiological monitoring instrumentation designed for use as post-accident monitors. The information was collated and published in the NSAC Handbook of Postaccident Instrumentation (Kathren and Laughlin 1981), and included such data as range, accuracy, precision, sensitivity, and energy dependence of the detector, environmental and seismic limitations of the equipment, the testing program performed to evaluate the equipment, a list of references where the instrumentation is currently installed, and a list of features and accessories available with the monitoring systems. The information presented in this section reveals that, even though a number of vendors claim to be able to meet the guidance of Regulatory Guide 1.97 (USNRC 1980), few have actually conducted tests to verify that their equipment does indeed satisfy the guidance of this Regulatory Guide, and that some of the guidance may in fact be unrealistic

  14. Enhancing AP1000 reactor accident management capabilities for long term accidents

    International Nuclear Information System (INIS)

    Jiang Pingting; Liu Mengying; Duan Chengjie; Liao Yehong

    2015-01-01

    Passive safety actions are considered as main measures under severe accident in AP1000 power plant. However, risk is still existed. According to PSA, several probable scenarios for AP1000 nuclear power plant are analyzed in this paper with MAAP the severe accident analysis code. According to the analysis results, several deficiencies of AP1000 severe accident management are found. The long term cooling and containment depressurization capability for AP1000 power plant appear to be most important factors under such accidents. Then, several temporary strategies for AP1000 power plant are suggested, including PCCWST temporary water supply strategy after 72h, temporary injection strategy for IRWST, hydrogen relief action in fuel building, which would improve the safety of AP1000 power plant. At last, assessments of effectiveness for these strategies are performed, and the results are compared with analysis without these strategies. The comparisons showed that correct actions of these strategies would effectively prevent the accident process of AP1000 power plant. (author)

  15. Implications of the Chernobyl accident for Protective Action Guidance

    International Nuclear Information System (INIS)

    Miller, Charles W.; Pepper, Andrea J.

    1989-01-01

    The accident that occurred at Unit 4 of the nuclear power station at Chernobyl in the Union of Soviet Socialist Republics on April 26, 1986, was the worst accident in the history of nuclear power. Thirty-one workers and emergency personnel died and more than 200 site personnel were hospitalized as a result of this event Approximately 135,000 persons within 30 km around the reactor were evacuated, and radioactive debris was spread throughout the Northern Hemisphere. There was much public concern generated around the world, and an increased risk of fatal cancel in the world's population is possible as a result of exposure to Chernobyl fallout (USNRC, 1987a). Since the time the Chernobyl accident occurred, many authoritative studies have been published, e.g. USNRC, 1987a. In these studies, differences in design between commercial U.S. reactors and the RBMK pressure-tube reactor at Chernobyl have been emphasized, e.g. USNRC, 1987b. While significant differences in design do exist between these reactors, we believe there are still significant lessons to be learned from the Chernobyl accident for U.S. reactors. The purpose of this paper is to summarize some of the major lessons to be learned related to protective action guidance. The Illinois Department of Nuclear Safety (IDNS) has identified three areas related to protective action guidance for food and water where implications can be drawn from Chernobyl for the U.S.: (1) uniformity of Protective Action Guides (PAGs), (2) incompleteness of U.S. PAGs, and (3) international communications. Following the Chernobyl accident, a variety of protective actions were undertaken by various nations. Furthermore, these actions were initiated, modified, and terminated at different times in different places and, in some instances, were applied on a local or regional basis rather than a national basis (Goldman et al., 1987). One result of this differing application of PAGs was the generation of considerable confusion among decision

  16. The Chernobyl accident consequences; Consequences de l'accident de Tchernobyl

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    Five teen years later, Tchernobyl remains the symbol of the greater industrial nuclear accident. To take stock on this accident, this paper proposes a chronology of the events and presents the opinion of many international and national organizations. It provides also web sites references concerning the environmental and sanitary consequences of the Tchernobyl accident, the economic actions and propositions for the nuclear safety improvement in the East Europe. (A.L.B.)

  17. NIF: Impacts of chemical accidents and comparison of chemical/radiological accident approaches

    International Nuclear Information System (INIS)

    Lazaro, M.A.; Policastro, A.J.; Rhodes, M.

    1996-01-01

    The US Department of Energy (DOE) proposes to construct and operate the National Ignition Facility (NIF). The goals of the NIF are to (1) achieve fusion ignition in the laboratory for the first time by using inertial confinement fusion (ICF) technology based on an advanced-design neodymium glass solid-state laser, and (2) conduct high-energy-density experiments in support of national security and civilian applications. The primary focus of this paper is worker-public health and safety issues associated with postulated chemical accidents during the operation of NIF. The key findings from the accident analysis will be presented. Although NIF chemical accidents will be emphasized, the important differences between chemical and radiological accident analysis approaches and the metrics for reporting results will be highlighted. These differences are common EIS facility and transportation accident assessments

  18. Accidents in perspective

    International Nuclear Information System (INIS)

    Gittus, J.H.

    1989-01-01

    The nuclear industry perspective and the public perspective on big nuclear accidents and leukaemia near nuclear sites are discussed. The industry perspective is that big accidents are so unlikely as to be virtually impossible and that leukaemia is not specifically associated with nuclear installations. Clusters of cancer with statistical significance occur in major cities. The public perspective is coloured by a prejudice and myth: the fear of radiation. The big nuclear accident is seen therefore as much more unacceptable than any other big accident. Risks associated with Sizewell-B nuclear station and the liquid gas depot at Canvey Island are discussed. The facts and figures are presented as tables and graphs. Given conflicting interpretations of the leukaemia problem the public inclines towards the more pessimistic view. (author)

  19. A direct, single-step plasma arc-vitreous ceramic process for stabilizing spent nuclear fuels, sludges, and associated wastes

    International Nuclear Information System (INIS)

    Feng, X.; Einziger, R.E.; Eschenbach, R.C.

    1997-01-01

    A single-step plasma arc-vitreous ceramic (PAVC) process is described for converting spent nuclear fuel (SNF), SNF sludges, and associated wastes into a vitreous ceramic waste form. This proposed technology is built on extensive experience of nuclear waste form development and nuclear waste treatment using the commercially available plasma arc centrifugal (PAC) system. SNF elements will be loaded directly into a PAC furnace with minimum additives and converted into vitreous ceramics with up to 90 wt% waste loading. The vitreous ceramic waste form should meet the functional requirements for borosilicate glasses for permanent disposal in a geologic repository and for interim storage. Criticality safety would be ensured through the use of batch modes, and controlling the amount of fuel processed in one batch. The minimum requirements on SNF characterization and pretreatment, the one-step process, and minimum secondary waste generation may reduce treatment duration, radiation exposure, and treatment cost

  20. Assessment of accident energetics in LMFBR core-disruptive accidents

    International Nuclear Information System (INIS)

    Fauske, H.K.

    1977-01-01

    An assessment of accident energetics in LMFBR core-disruptive accidents is given with emphasis on the generic issues of energetic recriticality and energetic fuel-coolant interaction events. Application of a few general behavior principles to the oxide-fueled system suggests that such events are highly unlikely following a postulated core meltdown event

  1. Radiation, accidents, society

    International Nuclear Information System (INIS)

    1988-01-01

    This book is meant to be used as a reference book for information officers at the event of a nuclear accident. The main part is edited in alphabetical order to facilitate use under stress. The book gives a short review of the health risks of radiation, and descriptions of accidents that have occured. The index words that have been chosen for the main part of the book have been selected due to experiences in connection with incidents and accidents. (L.E.)

  2. Regional Geologic Evaluations for Disposal of HLW and SNF: The Pierre Shale of the Northern Great Plains

    Energy Technology Data Exchange (ETDEWEB)

    Perry, Frank Vinton [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kelley, Richard E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-14

    The DOE Spent Fuel and Waste Technology (SWFT) R&D Campaign is supporting research on crystalline rock, shale (argillite) and salt as potential host rocks for disposal of HLW and SNF in a mined geologic repository. The distribution of these three potential repository host rocks is limited to specific regions of the US and to different geologic and hydrologic environments (Perry et al., 2014), many of which may be technically suitable as a site for mined geologic disposal. This report documents a regional geologic evaluation of the Pierre Shale, as an example of evaluating a potentially suitable shale for siting a geologic HLW repository. This report follows a similar report competed in 2016 on a regional evaluation of crystalline rock that focused on the Superior Province of the north-central US (Perry et al., 2016).

  3. Occupational Accidents And Preventive Measures

    CERN Document Server

    Fassnacht, V

    2006-01-01

    This report presents the 2005 statistics concerning occupational accidents involving members of the CERN personnel and contractors' personnel. It sets out the accident frequency and severity rates and provides a breakdown of accidents by cause and injury. It also contains a summary analysis of the most serious accidents and the associated recommendations.

  4. Safety regulations regarding to accident monitoring and accident sampling at Russian NPPs with VVER type reactors

    International Nuclear Information System (INIS)

    Sharafutdinov, Rachet; Lankin, Michail; Kharitonova, Nataliya

    2014-01-01

    The paper describes a tendency by development of regulatory document requirements related to accident monitoring and accident sampling at Russia's NPPs. Lessons learned from the Fukushima Daiichi accident pointed at the importance and necessary to carry out an additional safety check at Russia's nuclear power plants in the preparedness for management of severe accidents at NPPs. Planned measures for improvement of severe accidents management include development and implementation of the accident instrumentation systems, providing, monitoring, management and storage of information in a severe accident conditions. The draft of Safety Guidelines <accident monitoring system of nuclear power plants with VVER reactors' prepared by Scientific and Engineering Centre for Nuclear and Radiation Safety (SEC NRS) established the main criteria for accident monitoring instrumentation that can monitor relevant plant parameters in the reactor and inside containment during and after a severe accident in nuclear power plants. Development of these safety guidelines is in line with the recommendations of IAEA Action Plan on Nuclear Safety in response to the Fukushima Daiichi event and recommendations of the IAEA Nuclear Energy series Report <<Accident Monitoring Systems for Nuclear Power Plants' (Draft V 2.7). The paper presents the principles, which are used as the basis for selection of plant parameters for accident monitoring and for establishing of accident monitoring instrumentation. The recommendations to the accident sampling system capable to obtain the representative reactor coolant and containment air and fluid samples that support accurate analytical results for the parameters of interest are considered. The radiological and chemistry parameters to be monitored for primary coolant and sump and for containment air are specified. (author)

  5. Nuclear accidents and epidemiology

    International Nuclear Information System (INIS)

    1987-01-01

    A consultation on epidemiology related to the Chernobyl accident was held in Copenhagen in May 1987 as a basis for concerted action. This was followed by a joint IAEA/WHO workshop in Vienna, which reviewed appropriate methodologies for possible long-term effects of radiation following nuclear accidents. The reports of these two meetings are included in this volume, and cover the subjects: 1) Epidemiology related to the Chernobyl nuclear accident. 2) Appropriate methodologies for studying possible long-term effects of radiation on individuals exposed in a nuclear accident. Figs and tabs

  6. Reactivity insertion accident analysis

    International Nuclear Information System (INIS)

    Moreira, J.M.L.; Nakata, H.; Yorihaz, H.

    1990-04-01

    The correct prediction of postulated accidents is the fundamental requirement for the reactor licensing procedures. Accident sequences and severity of their consequences depend upon the analysis which rely on analytical tools which must be validated against known experimental results. Present work presents a systematic approach to analyse and estimate the reactivity insertion accident sequences. The methodology is based on the CINETHICA code which solves the point-kinetics/thermohydraulic coupled equations with weighted temperature feedback. Comparison against SPERT experimental results shows good agreement for the step insertion accidents. (author) [pt

  7. REAC/TS radiation accident registry. Update of accidents in the United States

    International Nuclear Information System (INIS)

    Ricks, R.C.; Berger, M.E.; Holloway, E.C.; Goans, R.E.

    2000-01-01

    Serious injury due to ionizing radiation is a rare occurrence. From 1944 to the present, 243 US accidents meeting dose criteria for classification as serious are documented in the REAC/TS Registry. Thirty individuals have lost their lives in radiation accidents in the United States. The Registry is part of the overall REAC/TS program providing 24-hour direct or consultative assistance regarding medical and heath physics problems associated with radiation accidents in local, national, and international incidents. The REAC/TS Registry serves as a repository of medically important information documenting the consequences of these accidents. Registry data are gathered from various sources. These include reports from the World Heath Organization (WHO), International Atomic Energy Agency (IAEA), US Nuclear Regulatory Commission (US NRC), state radiological health departments, medical/health physics literature, personal communication, the Internet, and most frequently, from calls for medical assistance to REAC/TS, as part of our 24-hour medical assistance program. The REAC/TS Registry for documentation of radiation accidents serves several useful purposes: 1) weaknesses in design, safety practices, training or control can be identified, and trends noted; 2) information regarding the medical consequences of injuries and the efficacy of treatment protocols is available to the treating physician; and 3) Registry case studies serve as valuable teaching tools. This presentation will review and summarize data on the US radiation accidents including their classification by device, accident circumstances, and frequency by respective states. Data regarding accidents with fatal outcomes will be reviewed. The inclusion of Registry data in the IAEA's International Reporting System of Radiation Events (RADEV) will also be discussed. (author)

  8. A gap analysis of meteorological requirements for commercial space operators

    Science.gov (United States)

    Stapleton, Nicholas James

    Commercial space companies will soon be the primary method of launching people and supplies into orbit. Among the critical aspects of space launches are the meteorological concerns. Laws and regulations pertaining to meteorological considerations have been created to ensure the safety of the space industry and those living around spaceports; but, are they adequate? Perhaps the commercial space industry can turn to the commercial aviation industry to help answer that question. Throughout its history, the aviation industry has dealt with lessons learned from mishaps due to failures in understanding the significance of weather impacts on operations. Using lessons from the aviation industry, the commercial space industry can preempt such accidents and maintain viability as an industry. Using Lanicci's Strategic Planning Model, this study identified the weather needs of the commercial space industry by conducting three gap analyses. First, a comparative analysis was done between laws and regulations in commercial aviation and those in the commercial space industry pertaining to meteorological support, finding a "legislative gap" between the two industries, as no legal guarantee is in place to ensure weather products remain available to the commercial space industry. A second analysis was conducted between the meteorological services provided for the commercial aviation industry and commercial space industry, finding a gap at facilities not located at an established launch facility or airport. At such facilities, many weather observational technologies would not be present, and would need to be purchased by the company operating the spaceport facility. A third analysis was conducted between the meteorological products and regulations that are currently in existence, and those needed for safe operations within the commercial space industry, finding gaps in predicting lightning, electric field charge, and space weather. Recommendations to address these deficiencies have

  9. Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins

    International Nuclear Information System (INIS)

    Korzhnev, Dmitry M.; Neculai, Dante; Dhe-Paganon, Sirano; Arrowsmith, Cheryl H.; Bezsonova, Irina

    2016-01-01

    HLTF is a SWI2/SNF2-family ATP-dependent chromatin remodeling enzyme that acts in the error-free branch of DNA damage tolerance (DDT), a cellular mechanism that enables replication of damaged DNA while leaving damage repair for a later time. Human HLTF and a closely related protein SHPRH, as well as their yeast homologue Rad5, are multi-functional enzymes that share E3 ubiquitin-ligase activity required for activation of the error-free DDT. HLTF and Rad5 also function as ATP-dependent dsDNA translocases and possess replication fork reversal activities. Thus, they can convert Y-shaped replication forks into X-shaped Holliday junction structures that allow error-free replication over DNA lesions. The fork reversal activity of HLTF is dependent on 3′-ssDNA-end binding activity of its N-terminal HIRAN domain. Here we present the solution NMR structure of the human HLTF HIRAN domain, an OB-like fold module found in organisms from bacteria (as a stand-alone domain) to plants, fungi and metazoan (in combination with SWI2/SNF2 helicase-like domain). The obtained structure of free HLTF HIRAN is similar to recently reported structures of its DNA bound form, while the NMR analysis also reveals that the DNA binding site of the free domain exhibits conformational heterogeneity. Sequence comparison of N-terminal regions of HLTF, SHPRH and Rad5 aided by knowledge of the HLTF HIRAN structure suggests that the SHPRH N-terminus also includes an uncharacterized structured module, exhibiting weak sequence similarity with HIRAN regions of HLTF and Rad5, and potentially playing a similar functional role.

  10. Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins

    Energy Technology Data Exchange (ETDEWEB)

    Korzhnev, Dmitry M. [University of Connecticut Health, Department of Molecular Biology and Biophysics (United States); Neculai, Dante [Zhejiang University, School of Medicine (China); Dhe-Paganon, Sirano [Dana-Farber Cancer Institute, Department of Cancer Biology (United States); Arrowsmith, Cheryl H. [University of Toronto, Structural Genomics Consortium (Canada); Bezsonova, Irina, E-mail: bezsonova@uchc.edu [University of Connecticut Health, Department of Molecular Biology and Biophysics (United States)

    2016-11-15

    HLTF is a SWI2/SNF2-family ATP-dependent chromatin remodeling enzyme that acts in the error-free branch of DNA damage tolerance (DDT), a cellular mechanism that enables replication of damaged DNA while leaving damage repair for a later time. Human HLTF and a closely related protein SHPRH, as well as their yeast homologue Rad5, are multi-functional enzymes that share E3 ubiquitin-ligase activity required for activation of the error-free DDT. HLTF and Rad5 also function as ATP-dependent dsDNA translocases and possess replication fork reversal activities. Thus, they can convert Y-shaped replication forks into X-shaped Holliday junction structures that allow error-free replication over DNA lesions. The fork reversal activity of HLTF is dependent on 3′-ssDNA-end binding activity of its N-terminal HIRAN domain. Here we present the solution NMR structure of the human HLTF HIRAN domain, an OB-like fold module found in organisms from bacteria (as a stand-alone domain) to plants, fungi and metazoan (in combination with SWI2/SNF2 helicase-like domain). The obtained structure of free HLTF HIRAN is similar to recently reported structures of its DNA bound form, while the NMR analysis also reveals that the DNA binding site of the free domain exhibits conformational heterogeneity. Sequence comparison of N-terminal regions of HLTF, SHPRH and Rad5 aided by knowledge of the HLTF HIRAN structure suggests that the SHPRH N-terminus also includes an uncharacterized structured module, exhibiting weak sequence similarity with HIRAN regions of HLTF and Rad5, and potentially playing a similar functional role.

  11. Investigation of Qom Rural Area Water Network Accident in 2010 and Minimization Approaches of Accident Frequencies

    Directory of Open Access Journals (Sweden)

    Hossein Jafari Mansoorian

    2016-02-01

    Full Text Available Background & Aims of the Study : Accidents in water networks can lead to increase the uncounted water, costs of repair, maintenance, restoration and enter water contaminants to water network. The aim of this study is to survey the accidents of Qom rural water network and choose the right approaches to reduce the number of accidents. Materials & Methods: In this cross-sectional study, four sector of Qom province (Markazi, Dastjerd, Kahak and Qahan, were assessed over a period of 8 months (July – January 2010. This study was conducted through questionnaire of Ministry of Energy. Results: The total number of accidents was 763. The highest number of accidents in the four sectors was related to Markazi sector with 228 accidents. According to the time of the accident, the highest and lowest number of accident was related to September (19.7% and November (6.8%, respectively. According to the location of the accident on network, the highest and lowest number of accident was related to distribution network (64% and connections (17.5% and transmission pipe (18.34%, respectively. According to the type of the accident, the highest and lowest number of accident was related to breaking (47.8% and gasket failure (1.2%, respectively. Considering with the pipes’ material, the highest and lowest number of accident was related to polyethylene pipes (93% and steel and cast iron pipes (0.5%, 0.5%, respectively. Conclusions: Due to the high break rate of Polyethylene pipes, it is recommended to be placed in priority of leak detection and rehabilitation.   .

  12. Independent assessment of MELCOR as a severe accident thermal-hydraulic/source term analysis tool

    International Nuclear Information System (INIS)

    Madni, I.K.; Eltawila, F.

    1994-01-01

    MELCOR is a fully integrated computer code that models all phases of the progression of severe accidents in light water reactor nuclear power plants, and is being developed for the US Nuclear Regulatory Commission (NRC) by Sandia National Laboratories (SNL). Brookhaven National Laboratory (BNL) has a program with the NRC called ''MELCOR Verification, Benchmarking, and Applications,'' whose aim is to provide independent assessment of MELCOR as a severe accident thermal-hydraulic/source term analysis tool. The scope of this program is to perform quality control verification on all released versions of MELCOR, to benchmark MELCOR against more mechanistic codes and experimental data from severe fuel damage tests, and to evaluate the ability of MELCOR to simulate long-term severe accident transients in commercial LWRs, by applying the code to model both BWRs and PWRs. Under this program, BNL provided input to the NRC-sponsored MELCOR Peer Review, and is currently contributing to the MELCOR Cooperative Assessment Program (MCAP). This paper presents a summary of MELCOR assessment efforts at BNL and their contribution to NRC goals with respect to MELCOR

  13. [Diving accidents. Emergency treatment of serious diving accidents].

    Science.gov (United States)

    Schröder, S; Lier, H; Wiese, S

    2004-11-01

    Decompression injuries are potentially life-threatening incidents mainly due to a rapid decline in ambient pressure. Decompression illness (DCI) results from the presence of gas bubbles in the blood and tissue. DCI may be classified as decompression sickness (DCS) generated from the liberation of gas bubbles following an oversaturation of tissues with inert gas and arterial gas embolism (AGE) mainly due to pulmonary barotrauma. People working under hyperbaric pressure, e.g. in a caisson for general construction under water, and scuba divers are exposed to certain risks. Diving accidents can be fatal and are often characterized by organ dysfunction, especially neurological deficits. They have become comparatively rare among professional divers and workers. However, since recreational scuba diving is gaining more and more popularity there is an increasing likelihood of severe diving accidents. Thus, emergency staff working close to areas with a high scuba diving activity, e.g. lakes or rivers, may be called more frequently to a scuba diving accident. The correct and professional emergency treatment on site, especially the immediate and continuous administration of normobaric oxygen, is decisive for the outcome of the accident victim. The definitive treatment includes rapid recompression with hyperbaric oxygen. The value of adjunctive medication, however, remains controversial.

  14. Criticality accident:

    International Nuclear Information System (INIS)

    Canavese, Susana I.

    2000-01-01

    A criticality accident occurred at 10:35 on September 30, 1999. It occurred in a precipitation tank in a Conversion Test Building at the JCO Tokai Works site in Tokaimura (Tokai Village) in the Ibaraki Prefecture of Japan. STA provisionally rated this accident a 4 on the seven-level, logarithmic International Nuclear Event Scale (INES). The September 30, 1999 criticality accident at the JCO Tokai Works Site in Tokaimura, Japan in described in preliminary, technical detail. Information is based on preliminary presentations to technical groups by Japanese scientists and spokespersons, translations by technical and non-technical persons of technical web postings by various nuclear authorities, and English-language non-technical reports from various news media and nuclear-interest groups. (author)

  15. Reactor safety study. An assessment of accident risks in U.S. commercial nuclear power plants. Appendix XI. Analysis of comments on the draft WASH-1400 report

    International Nuclear Information System (INIS)

    1975-10-01

    Information is presented concerning comments on reactor safety by governmental agencies and civilian organizations; reactor safety study methodology; consequence model; probability of accident sequences; and various accident conditions

  16. Potential information requirements for spent nuclear fuel

    International Nuclear Information System (INIS)

    Disbrow, J.A.

    1991-01-01

    This paper reports that the Energy Information Administration (EIA) has performed analyses of the requirements for data and information for the management of commercial spent nuclear fuel (SNF) designated for disposal under the Nuclear Waste Policy Act (NWPA). Subsequently, the EIA collected data on the amounts and characteristics of SNF stored at commercial nuclear facilities. Most recently, the EIA performed an analysis of the international and domestic laws and regulations which have been established to ensure the safeguarding, accountability, and safe management of special nuclear materials (SNM). The SNM of interest are those designated for permanent disposal by the NWPA. This analysis was performed to determine what data and information may be needed to fulfill the specific accountability responsibilities of the Department of Energy (DOE) related to SNF handling, transportation, storage and disposal; to work toward achieving a consistency between nuclear fuel assembly identifiers and material weights as reported by the various responsible parties; and to assist in the revision of the Nuclear Fuel Data Form RW-859 used to obtain spent nuclear fuel characteristics data from the nuclear utilities

  17. Accident management information needs

    International Nuclear Information System (INIS)

    Hanson, D.J.; Ward, L.W.; Nelson, W.R.; Meyer, O.R.

    1990-04-01

    In support of the US Nuclear Regulatory Commission (NRC) Accident Management Research Program, a methodology has been developed for identifying the plant information needs necessary for personnel involved in the management of an accident to diagnose that an accident is in progress, select and implement strategies to prevent or mitigate the accident, and monitor the effectiveness of these strategies. This report describes the methodology and presents an application of this methodology to a Pressurized Water Reactor (PWR) with a large dry containment. A risk-important severe accident sequence for a PWR is used to examine the capability of the existing measurements to supply the necessary information. The method includes an assessment of the effects of the sequence on the measurement availability including the effects of environmental conditions. The information needs and capabilities identified using this approach are also intended to form the basis for more comprehensive information needs assessment performed during the analyses and development of specific strategies for use in accident management prevention and mitigation. 3 refs., 16 figs., 7 tabs

  18. Accident management information needs

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, D.J.; Ward, L.W.; Nelson, W.R.; Meyer, O.R. (EG and G Idaho, Inc., Idaho Falls, ID (USA))

    1990-04-01

    In support of the US Nuclear Regulatory Commission (NRC) Accident Management Research Program, a methodology has been developed for identifying the plant information needs necessary for personnel involved in the management of an accident to diagnose that an accident is in progress, select and implement strategies to prevent or mitigate the accident, and monitor the effectiveness of these strategies. This report describes the methodology and presents an application of this methodology to a Pressurized Water Reactor (PWR) with a large dry containment. A risk-important severe accident sequence for a PWR is used to examine the capability of the existing measurements to supply the necessary information. The method includes an assessment of the effects of the sequence on the measurement availability including the effects of environmental conditions. The information needs and capabilities identified using this approach are also intended to form the basis for more comprehensive information needs assessment performed during the analyses and development of specific strategies for use in accident management prevention and mitigation. 3 refs., 16 figs., 7 tabs.

  19. Estimating the Influence of Accident Related Factors on Motorcycle Fatal Accidents using Logistic Regression (Case Study: Denpasar-Bali

    Directory of Open Access Journals (Sweden)

    Wedagama D.M.P.

    2010-01-01

    Full Text Available In Denpasar the capital of Bali Province, motorcycle accident contributes to about 80% of total road accidents. Out of those motorcycle accidents, 32% are fatal accidents. This study investigates the influence of accident related factors on motorcycle fatal accidents in the city of Denpasar during period 2006-2008 using a logistic regression model. The study found that the fatality of collision with pedestrians and right angle accidents were respectively about 0.44 and 0.40 times lower than collision with other vehicles and accidents due to other factors. In contrast, the odds that a motorcycle accident will be fatal due to collision with heavy and light vehicles were 1.67 times more likely than with other motorcycles. Collision with pedestrians, right angle accidents, and heavy and light vehicles were respectively accounted for 31%, 29%, and 63% of motorcycle fatal accidents.

  20. The Price-Anderson Act: A Linchpin in the Development of Commercial Nuclear Power in the United States

    International Nuclear Information System (INIS)

    Quattrocchi, J. L.

    2006-01-01

    The dawn of the atomic age brought with it both the hope of great benefit and the fear of great disaster. By the mid-1950's, the United States recognized that it was in the national interest to promote commercial development of nuclear energy in medicine and industry, particularly in the generation of electric power. The uncertainties of the technology and the potential for severe accidents were clear obstacles to commercial development. Exposure to potentially serious uninsured liabilities inhibited the private sector. These impediments led Congress to enact the Price-Anderson Act in 1957. Its three-fold purpose was to encourage private development of nuclear power, establish a framework for handling liability claims and provide a ready source of funds to compensate accident victims. The law was originally enacted for ten years but has now been extended four times. The major provisions of the Act and its importance to the public and to insurers are described in this paper.(author)

  1. Approach and results of the PWR low power and shutdown accident frequencies program - Coarse screening analysis for Surry

    International Nuclear Information System (INIS)

    Chu, T.L.; Musicki, Z.; Luckas, W.; Wong, S.M.; Fitzpatrick, R.G.

    1991-01-01

    Traditionally, probabilistic risk analyses of severe accidents in nuclear power plants have limited themselves to consideration of the set of initiating events occurring during full power operation. However, some analyses of accident initiators during low power, shutdown, and other modes of plant operation other than full power have been performed. These studies as well as the Chernobyl accident and recent operating experience at US pressurized water reactors (PWRs) suggested that risks during low power and shutdown could be significant. As such, the analysis of the frequencies, consequences, and risks of these accidents was identified as one task in the Nuclear Regulatory Commission staff's study of the implications of the Chernobyl accident to US commercial nuclear power plants. This program is an ongoing high priority effort at Brookhaven National Laboratory (BNL). The scope includes a Level 1 probabilistic risk assessment (PRA) with internal fire and flood for Surry Unit 1 (PWR). This program is also closely coupled to a parallel project for the Grand Gulf plant (BWWR) being conducted by SNL. The program is being performed in two phases. Phase 1 represents a coarse screening analysis to identify dominant accident scenarios as well as risk dominant plant configurations and plant operating states. In Phase 2, a detailed PRA will be performed for the dominant accident scenarios/operating states identified in Phase 1. The objectives, results and insights of Phase 1 are discussed in the paper

  2. Big nuclear accidents

    International Nuclear Information System (INIS)

    Marshall, W.; Billingon, D.E.; Cameron, R.F.; Curl, S.J.

    1983-09-01

    Much of the debate on the safety of nuclear power focuses on the large number of fatalities that could, in theory, be caused by extremely unlikely but just imaginable reactor accidents. This, along with the nuclear industry's inappropriate use of vocabulary during public debate, has given the general public a distorted impression of the risks of nuclear power. The paper reviews the way in which the probability and consequences of big nuclear accidents have been presented in the past and makes recommendations for the future, including the presentation of the long-term consequences of such accidents in terms of 'loss of life expectancy', 'increased chance of fatal cancer' and 'equivalent pattern of compulsory cigarette smoking'. The paper presents mathematical arguments, which show the derivation and validity of the proposed methods of presenting the consequences of imaginable big nuclear accidents. (author)

  3. Radiological accidents in medical practice

    International Nuclear Information System (INIS)

    Cardenas Herrera, Juan

    2012-01-01

    Different radiological accidents that may occur in medical practice are shown. The following topics are focused: accident statistics for medical exposure, accidental medical exposures, radiotherapy accidents and potential accidental scenarios [es

  4. Sports Accidents

    CERN Multimedia

    Kiebel

    1972-01-01

    Le Docteur Kiebel, chirurgien à Genève, est aussi un grand ami de sport et de temps en temps médecin des classes genevoises de ski et également médecin de l'équipe de hockey sur glace de Genève Servette. Il est bien qualifié pour nous parler d'accidents de sport et surtout d'accidents de ski.

  5. [Accidents in travellers - the hidden epidemic].

    Science.gov (United States)

    Walz, Alexander; Hatz, Christoph

    2013-06-01

    The risk of malaria and other communicable diseases is well addressed in pre-travel advice. Accidents are usually less discussed. Thus, we aimed at assessing accident figures for the Swiss population, based on data of the register from 2004 to 2008 of the largest Swiss accident insurance organization (SUVA). More than 139'000 accidents over 5 years showed that 65 % of the accidents overseas are injuries, and 24 % are caused by poisoning or harm by cold, heat or air pressure. Most accidents happened during leisure activities or sports. More than one third of the non-lethal and more than 50 % of the fatal accidents happened in Asia. More than three-quarters of non-lethal accidents take place in people between 25 and 54 years. One out of 74 insured persons has an accident abroad per year. Despite of many analysis short-comings of the data set with regard to overseas travel, the figures document the underestimated burden of disease caused by accidents abroad and should affect the given pre-health advice.

  6. Occupational accidents among mototaxi drivers.

    Science.gov (United States)

    Amorim, Camila Rego; de Araújo, Edna Maria; de Araújo, Tânia Maria; de Oliveira, Nelson Fernandes

    2012-03-01

    The use of motorcycles as a means of work has contributed to the increase in traffic accidents, in particular, mototaxi accidents. The aim of this study was to estimate and characterize the incidence of occupational accidents among the mototaxis registered in Feira de Santana, BA. This is a cross-sectional study with descriptive and census data. Of the 300 professionals registered at the Municipal Transportation Service, 267 professionals were interviewed through a structured questionnaire. Then, a descriptive analysis was conducted and the incidence of accidents was estimated based on the variables studied. Relative risks were calculated and statistical significance was determined using the chi-square test and Fisher's exact test, considering p accidents were observed in 10.5% of mototaxis. There were mainly minor injuries (48.7%), 27% of them requiring leaves of absence from work. There was an association between the days of work per week, fatigue in lower limbs and musculoskeletal complaints, and accidents. Knowledge of the working conditions and accidents involved in this activity can be of great importance for the adoption of traffic education policies, and to help prevent accidents by improving the working conditions and lives of these professionals.

  7. Evaluation of the Three Mile Island accident in the context of WASH-1400

    International Nuclear Information System (INIS)

    Burns, R.D. III.

    1980-01-01

    The accident at unit 2 of the Three Mile Island nuclear station (TMI-2) on March 28, 1979, occurred after approximately 400 reactor years (RY) of commercial nuclear reactor operation in the US. The purpose of work summarized here was to evaluate the probability statements in the WASH-1400 reactor safety study (RSS) in view of the TMI-2 event and to estimate the likely public impact of TMI-2. The RSS probability estimate for such a release was found to be consistent with the fact that the TMI-2 accident occurred. The expected health effects are consistent with those for a low-level category of radioactivity release as described in the RSS and they are immeasurably small. However, the public perception of the health effects of the release is likely to be much more severe than the estimated health effects

  8. The application of the assessment of nuclear accident status in emergency decision-making during nuclear accident

    International Nuclear Information System (INIS)

    Yang Ling

    2011-01-01

    Nuclear accident assessment is one of the bases for emergency decision-making in the situation of nuclear accident in NPP. Usually, the assessment includes accident status and consequence assessment. It is accident status assessment, and its application in emergency decision-making is introduced here. (author)

  9. Severe accident management. Prevention and Mitigation

    International Nuclear Information System (INIS)

    1992-01-01

    Effective planning for the management of severe accidents at nuclear power plants can produce both a reduction in the frequency of such accidents as well as the ability to mitigate their consequences if and when they should occur. This report provides an overview of accident management activities in OECD countries. It also presents the conclusions of a group of international experts regarding the development of accident management methods, the integration of accident management planning into reactor operations, and the benefits of accident management

  10. The Analysis of the Contribution of Human Factors to the In-Flight Loss of Control Accidents

    Science.gov (United States)

    Ancel, Ersin; Shih, Ann T.

    2012-01-01

    In-flight loss of control (LOC) is currently the leading cause of fatal accidents based on various commercial aircraft accident statistics. As the Next Generation Air Transportation System (NextGen) emerges, new contributing factors leading to LOC are anticipated. The NASA Aviation Safety Program (AvSP), along with other aviation agencies and communities are actively developing safety products to mitigate the LOC risk. This paper discusses the approach used to construct a generic integrated LOC accident framework (LOCAF) model based on a detailed review of LOC accidents over the past two decades. The LOCAF model is comprised of causal factors from the domain of human factors, aircraft system component failures, and atmospheric environment. The multiple interdependent causal factors are expressed in an Object-Oriented Bayesian belief network. In addition to predicting the likelihood of LOC accident occurrence, the system-level integrated LOCAF model is able to evaluate the impact of new safety technology products developed in AvSP. This provides valuable information to decision makers in strategizing NASA's aviation safety technology portfolio. The focus of this paper is on the analysis of human causal factors in the model, including the contributions from flight crew and maintenance workers. The Human Factors Analysis and Classification System (HFACS) taxonomy was used to develop human related causal factors. The preliminary results from the baseline LOCAF model are also presented.

  11. Casebook on electric safety accidents

    International Nuclear Information System (INIS)

    1987-09-01

    This book gives concentration on electric safety accidents in domestic and abroad, which introduces general electrical safety with property of electricity, safe equipment and maintenance and protection of electric shock. It lists the cases of accident caused of electricity in domestic like accident in power substation, utilization equipment, load system and another accident by electricity like death in electric shock another by electricity like death in electric shock in new building construction, the cases caused of electricity in abroad like damage in electric shock by high voltage electric transformer, electric shock in summer and earth fault accident by fault cooling tower.

  12. Radiological accidents balance in medicine

    International Nuclear Information System (INIS)

    Nenot, J.C.

    1995-01-01

    This work deals with the radiological accidents in medicine. In medicine, the radiation accidents on medical personnel and patients can be the result of over dosage and bad focusing of radiotherapy sealed sources. Sometimes, the accidents, if they are unknown during a time enough for the source to be spread and to expose a lot of persons (in the case of source dismantling for instance) can take considerable dimensions. Others accidents can come from bad handling of linear accelerators and from radionuclide kinetics in some therapies. Some examples of accidents are given. (O.L.). 11 refs

  13. A study on industrial accident rate forecasting and program development of estimated zero accident time in Korea.

    Science.gov (United States)

    Kim, Tae-gu; Kang, Young-sig; Lee, Hyung-won

    2011-01-01

    To begin a zero accident campaign for industry, the first thing is to estimate the industrial accident rate and the zero accident time systematically. This paper considers the social and technical change of the business environment after beginning the zero accident campaign through quantitative time series analysis methods. These methods include sum of squared errors (SSE), regression analysis method (RAM), exponential smoothing method (ESM), double exponential smoothing method (DESM), auto-regressive integrated moving average (ARIMA) model, and the proposed analytic function method (AFM). The program is developed to estimate the accident rate, zero accident time and achievement probability of an efficient industrial environment. In this paper, MFC (Microsoft Foundation Class) software of Visual Studio 2008 was used to develop a zero accident program. The results of this paper will provide major information for industrial accident prevention and be an important part of stimulating the zero accident campaign within all industrial environments.

  14. Occupational accidents aboard merchant ships

    DEFF Research Database (Denmark)

    Hansen, H.L.; Nielsen, D.; Frydenberg, Morten

    2002-01-01

    Objectives: To investigate the frequency, circumstances, and causes of occupational accidents aboard merchant ships in international trade, and to identify risk factors for the occurrence of occupational accidents as well as dangerous working situations where possible preventive measures may...... be initiated. Methods: The study is a historical follow up on occupational accidents among crew aboard Danish merchant ships in the period 1993–7. Data were extracted from the Danish Maritime Authority and insurance data. Exact data on time at risk were available. Results: A total of 1993 accidents were...... aboard. Relative risks for notified accidents and accidents causing permanent disability of 5% or more were calculated in a multivariate analysis including ship type, occupation, age, time on board, change of ship since last employment period, and nationality. Foreigners had a considerably lower recorded...

  15. Cernavoda CANDU severe accident evaluation

    International Nuclear Information System (INIS)

    Negut, G.; Marin, A.

    1997-01-01

    The papers present the activities dedicated to Romania Cernavoda Nuclear Power Plant first CANDU Unit severe accident evaluation. This activity is part of more general PSA assessment activities. CANDU specific safety features are calandria moderator and calandria vault water capabilities to remove the residual heat in the case of severe accidents, when the conventional heat sinks are no more available. Severe accidents evaluation, that is a deterministic thermal hydraulic analysis, assesses the accidents progression and gives the milestones when important events take place. This kind of assessment is important to evaluate to recovery time for the reactor operators that can lead to the accident mitigation. The Cernavoda CANDU unit is modeled for the of all heat sinks accident and results compared with the AECL CANDU 600 assessment. (orig.)

  16. Preliminary safety analysis of the PWR with accident-tolerant fuels during severe accident conditions

    International Nuclear Information System (INIS)

    Wu, Xiaoli; Li, Wei; Wang, Yang; Zhang, Yapei; Tian, Wenxi; Su, Guanghui; Qiu, Suizheng; Liu, Tong; Deng, Yongjun; Huang, Heng

    2015-01-01

    Highlights: • Analysis of severe accident scenarios for a PWR fueled with ATF system is performed. • A large-break LOCA without ECCS is analyzed for the PWR fueled with ATF system. • Extended SBO cases are discussed for the PWR fueled with ATF system. • The accident-tolerance of ATF system for application in PWR is illustrated. - Abstract: Experience gained in decades of nuclear safety research and previous nuclear accidents direct to the investigation of passive safety system design and accident-tolerant fuel (ATF) system which is now becoming a hot research point in the nuclear energy field. The ATF system is aimed at upgrading safety characteristics of the nuclear fuel and cladding in a reactor core where active cooling has been lost, and is preferable or comparable to the current UO 2 –Zr system when the reactor is in normal operation. By virtue of advanced materials with improved properties, the ATF system will obviously slow down the progression of accidents, allowing wider margin of time for the mitigation measures to work. Specifically, the simulation and analysis of a large break loss of coolant accident (LBLOCA) without ECCS and extended station blackout (SBO) severe accident are performed for a pressurized water reactor (PWR) loaded with ATF candidates, to reflect the accident-tolerance of ATF

  17. A Study on the Operation Strategy for Combined Accident including TLOFW accident

    International Nuclear Information System (INIS)

    Kim, Bo Gyung; Kang, Gook Young; Yoon, Ho Joon

    2014-01-01

    It is difficult for operators to recognize the necessity of a feed-and-bleed (F-B) operation when the loss of coolant accident and failure of secondary side occur. An F-B operation directly cools down the reactor coolant system (RCS) using the primary cooling system when residual heat removal by the secondary cooling system is not available. The plant is not always necessary the F-B operation when the secondary side is failed. It is not necessary to initiate an F-B operation in the case of a medium or large break because these cases correspond to low RCS pressure sequences when the secondary side is failed. If the break size is too small to sufficiently decrease the RCS pressure, the F-B operation is necessary. Therefore, in the case of a combined accident including a secondary cooling system failure, the provision of clear information will play a critical role in the operators' decision to initiate an F-B operation. This study focuses on the how we establish the operation strategy for combined accident including the failure of secondary side in consideration of plant and operating conditions. Previous studies have usually focused on accidents involving a TLOFW accident. The plant conditions to make the operators confused seriously are usually the combined accident because the ORP only focuses on a single accident and FRP is less familiar with operators. The relationship between CET and PCT under various plant conditions is important to decide the limitation of initiating the F-B operation to prevent core damage

  18. Test Area North Pool Stabilization Project: Environmental assessment

    International Nuclear Information System (INIS)

    1996-05-01

    The Test Area North (TAN) Pool is located within the fenced TAN facility boundaries on the Idaho National Engineering Laboratory (INEL). The TAN pool stores 344 canisters of core debris from the March, 1979, Three Mile Island (TMI) Unit 2 reactor accident; fuel assemblies from Loss-of-Fluid Tests (LOFT); and Government-owned commercial fuel rods and assemblies. The LOFT and government owned commercial fuel rods and assemblies are hereafter referred to collectively as open-quotes commercial fuelsclose quotes except where distinction between the two is important to the analysis. DOE proposes to remove the canisters of TMI core debris and commercial fuels from the TAN Pool and transfer them to the Idaho Chemical Processing Plant (ICPP) for interim dry storage until an alternate storage location other than at the INEL, or a permanent federal spent nuclear fuel (SNF) repository is available. The TAN Pool would be drained and placed in an industrially and radiologically safe condition for refurbishment or eventual decommissioning. This environmental assessment (EA) identifies and evaluates environmental impacts associated with (1) constructing an Interim Storage System (ISS) at ICPP; (2) removing the TMI and commercial fuels from the pool and transporting them to ICPP for placement in an ISS, and (3) draining and stabilizing the TAN Pool. Miscellaneous hardware would be removed and decontaminated or disposed of in the INEL Radioactive Waste Management Complex (RWMC). This EA also describes the environmental consequences of the no action alternative

  19. Accidents in making fireworks. Tapaturmat polttopuun teossa

    Energy Technology Data Exchange (ETDEWEB)

    Solmio, H

    1991-01-01

    The accidents and the trends in the number of accidents and their causes were analyzed in a study conducted by the Forestry Department of the Work Efficiency Institute. The study was funded by the Finnish Agricultural Enterpreneurs' Pension Fund (MELA). The study material was selected from MELA's accident stage work and cause code. Altogether, the material comprised the following accidents that occurred while making and using firewood: 671 accidents in 1987 and 596 accidents in 1988. The amount of accidents caused by the working environment and hand tools was clearly higher in 1987 than in 1988. The number of accidents occurred while chopping wood was 20 % higher in 1987 than in 1988. April was the most accident-prone month both in 1987 and in 1988. Chopping of firewood was the most dangerous work stage in terms of the number of accidents. In 1988, the number of accidents in chopping firewood was 336, in sawing using circular saw 97 cases and other mechanized chopping led to 93 accidents. Heating with wood caused 33 accidents. In 1988 there were 10 (2 %) accidents involving loss of limbs and 9 of them occurred in the mechanized chopping of firewood. Nine accidents of these involved the loss of one or more fingers. Serious accidents, leading to inability to work for more than 3 months, were most frequent in chopping and in storing firewood.

  20. Psychophysiological Sensing and State Classification for Attention Management in Commercial Aviation

    Science.gov (United States)

    Harrivel, Angela R.; Liles, Charles; Stephens, Chad L.; Ellis, Kyle K.; Prinzel, Lawrence J.; Pope, Alan T.

    2016-01-01

    Attention-related human performance limiting states (AHPLS) can cause pilots to lose airplane state awareness (ASA), and their detection is important to improving commercial aviation safety. The Commercial Aviation Safety Team found that the majority of recent international commercial aviation accidents attributable to loss of control inflight involved flight crew loss of airplane state awareness, and that distraction of various forms was involved in all of them. Research on AHPLS, including channelized attention, diverted attention, startle / surprise, and confirmation bias, has been recommended in a Safety Enhancement (SE) entitled "Training for Attention Management." To accomplish the detection of such cognitive and psychophysiological states, a broad suite of sensors has been implemented to simultaneously measure their physiological markers during high fidelity flight simulation human subject studies. Pilot participants were asked to perform benchmark tasks and experimental flight scenarios designed to induce AHPLS. Pattern classification was employed to distinguish the AHPLS induced by the benchmark tasks. Unimodal classification using pre-processed electroencephalography (EEG) signals as input features to extreme gradient boosting, random forest and deep neural network multiclass classifiers was implemented. Multi-modal classification using galvanic skin response (GSR) in addition to the same EEG signals and using the same types of classifiers produced increased accuracy with respect to the unimodal case (90 percent vs. 86 percent), although only via the deep neural network classifier. These initial results are a first step toward the goal of demonstrating simultaneous real time classification of multiple states using multiple sensing modalities in high-fidelity flight simulators. This detection is intended to support and inform training methods under development to mitigate the loss of ASA and thus reduce accidents and incidents.

  1. Estimation of cost per severe accident for improvement of accident protection and consequence mitigation strategies

    International Nuclear Information System (INIS)

    Silva, Kampanart; Ishiwatari, Yuki; Takahara, Shogo

    2013-01-01

    To assess the complex situations regarding the severe accidents such as what observed in Fukushima Accident, not only radiation protection aspects but also relevant aspects: health, environmental, economic and societal aspects; must be all included into the consequence assessment. In this study, the authors introduce the “cost per severe accident” as an index to analyze the consequences of severe accidents comprehensively. The cost per severe accident consists of various costs and consequences converted into monetary values. For the purpose of improvement of the accident protection and consequence mitigation strategies, the costs needed to introduce the protective actions, and health and psychological consequences are included in the present study. The evaluations of these costs and consequences were made based on the systematic consequence analysis using level 2 and 3 probabilistic safety assessment (PSA) codes. The accident sequences used in this analysis were taken from the results of level 2 seismic PSA of a virtual 1,100 MWe BWR-5. The doses to the public and the number of people affected were calculated using the level 3 PSA code OSCAAR of Japan Atomic Energy Agency (JAEA). The calculations have been made for 248 meteorological sequences, and the outputs are given as expectation values for various meteorological conditions. Using these outputs, the cost per severe accident is calculated based on the open documents on the Fukushima Accident regarding the cost of protective actions and compensations for psychological harms. Finally, optimized accident protection and consequence mitigation strategies are recommended taking into account the various aspects comprehensively using the cost per severe accident. The authors must emphasize that the aim is not to estimate the accident cost itself but to extend the scope of “risk-informed decision making” for continuous safety improvements of nuclear energy. (author)

  2. A comparison of the hazard perception ability of accident-involved and accident-free motorcycle riders.

    Science.gov (United States)

    Cheng, Andy S K; Ng, Terry C K; Lee, Hoe C

    2011-07-01

    Hazard perception is the ability to read the road and is closely related to involvement in traffic accidents. It consists of both cognitive and behavioral components. Within the cognitive component, visual attention is an important function of driving whereas driving behavior, which represents the behavioral component, can affect the hazard perception of the driver. Motorcycle riders are the most vulnerable types of road user. The primary purpose of this study was to deepen our understanding of the correlation of different subtypes of visual attention and driving violation behaviors and their effect on hazard perception between accident-free and accident-involved motorcycle riders. Sixty-three accident-free and 46 accident-involved motorcycle riders undertook four neuropsychological tests of attention (Digit Vigilance Test, Color Trails Test-1, Color Trails Test-2, and Symbol Digit Modalities Test), filled out the Chinese Motorcycle Rider Driving Violation (CMRDV) Questionnaire, and viewed a road-user-based hazard situation with an eye-tracking system to record the response latencies to potentially dangerous traffic situations. The results showed that both the divided and selective attention of accident-involved motorcycle riders were significantly inferior to those of accident-free motorcycle riders, and that accident-involved riders exhibited significantly higher driving violation behaviors and took longer to identify hazardous situations compared to their accident-free counterparts. However, the results of the regression analysis showed that aggressive driving violation CMRDV score significantly predicted hazard perception and accident involvement of motorcycle riders. Given that all participants were mature and experienced motorcycle riders, the most plausible explanation for the differences between them is their driving style (influenced by an undesirable driving attitude), rather than skill deficits per se. The present study points to the importance of

  3. Severe accident behavior

    International Nuclear Information System (INIS)

    Denning, R.S.

    1986-01-01

    The purpose of this paper is to provide an overview of severe accident behavior. The term source term is defined and a brief history of the regulatory use of source term is presented. The processes in severe accidents in light water reactors are described with particular emphasis on the relationships between accident thermal-hydraulics and chemistry. Those factors which have the greatest impact on predicted source terms are identified. Design differences between plants that affect source term estimation are also described. The principal unresolved issues are identified that are the focus of ongoing research and debate in the technical community

  4. Construction industry accidents in Spain.

    Science.gov (United States)

    Camino López, Miguel A; Ritzel, Dale O; Fontaneda, Ignacio; González Alcantara, Oscar J

    2008-01-01

    This paper analyzed industrial accidents that take place on construction sites and their severity. Eighteen variables were studied. We analyzed the influence of each of these with respect to the severity and fatality of the accident. This descriptive analysis was grounded in 1,630,452 accidents, representing the total number of accidents suffered by workers in the construction sector in Spain over the period 1990-2000. It was shown that age, type of contract, time of accident, length of service in the company, company size, day of the week, and the remainder of the variables under analysis influenced the seriousness of the accident. IMPACT ON INJURY PREVENTION: The results obtained show that different training was needed, depending on the severity of accidents, for different age, length of service in the company, organization of work, and time when workers work. The research provides an insight to the likely causes of construction injuries in Spain. As a result of the analysis, industries and governmental agencies in Spain can start to provide appropriate strategies and training to the construction workers.

  5. Pilot program: NRC severe reactor accident incident response training manual: Severe reactor accident overview

    International Nuclear Information System (INIS)

    McKenna, T.J.; Martin, J.A.; Miller, C.W.; Hively, L.M.; Sharpe, R.W.; Giitter, J.G.; Watkins, R.M.

    1987-02-01

    This pilot training manual has been written to fill the need for a general text on NRC response to reactor accidents. The manual is intended to be the foundation for a course for all NRC response personnel. Severe Reactor Accident Overview is the second in a series of volumes that collectively summarize the US Nuclear Regulatory Commission (NRC) emergency response during severe power reactor accidents and provide necessary background information. This volume describes elementary perspectives on severe accidents and accident assesment. Each volume serves, respectively, as the text for a course of instruction in a series of courses. Each volume is accompanied by an appendix of slides that can be used to present this material. The slides are called out in the text

  6. Lessons learned from accidents investigations

    Energy Technology Data Exchange (ETDEWEB)

    Zuniga-Bello, P. [Consejo Nacional de Ciencia y Tecnologia (CONACYT), Mexico City (Mexico); Croft, J. [National Radiological Protection Board (United Kingdom); Glenn, J

    1997-12-31

    Accidents from three main practices: medical applications, industrial radiography and industrial irradiators are used to illustrate some common causes of accidents and the main lessons to be learned. A brief description of some of these accidents is given. Lessons learned from the described accidents are approached by subjects covering: safety culture, quality assurance, human factors, good engineering practice, defence in depth, security of sources, safety assessment and monitoring and verification compliance. (author)

  7. Lessons learned from accident investigations

    International Nuclear Information System (INIS)

    Zuniga-Bello, P.; Croft, J.R.; Glenn, J.

    1998-01-01

    Accidents in three main practices - medical applications, industrial radiography and industrial irradiators - are used to illustrate some common causes of accidents and the main lessons to be learned from them. A brief description of some of these accidents is given. Lessons learned from the accidents described are approached bearing in mind: safety culture, quality assurance, human factors, good engineering practice, defence in depth, security of sources, safety assessment and monitoring and verification compliance. (author)

  8. Socioeconomic consequences of nuclear reactor accidents

    International Nuclear Information System (INIS)

    Tawil, J.J.; Callaway, J.W.; Coles, B.L.; Cronin, F.J.; Currie, J.W.; Imhoff, K.L.; Lewis, P.M.; Nesse, R.J.; Strenge, D.L.

    1984-06-01

    This report identifies and characterizes the off-site socioeconomic consequences that would likely result from a severe radiological accident at a nuclear power plant. The types of impacts that are addressed include economic impacts, health impacts, social/psychological impacts and institutional impacts. These impacts are identified for each of several phases of a reactor accident - from the warning phase through the post-resettlement phase. The relative importance of the impact during each accident phase and the degree to which the impact can be predicted are indicated. The report also examines the methods that are currently used for assessing nuclear reactor accidents, including development of accident scenarios and the estimating of socioeconomic accident consequences with various models. Finally, a critical evaluation is made regarding the use of impact analyses in estimating the contribution of socioeconomic consequences to nuclear accident reactor accident risk. 116 references, 7 figures, 15 tables

  9. Radiation accidents

    International Nuclear Information System (INIS)

    Poplavskij, K.K.; Smorodintseva, G.I.

    1978-01-01

    On the basis of a critical analysis of the available data on causes and consequences of radiation accidents (RA), a classification of RA by severity (five groups of accidents) according to biomedical consequences and categories of exposed personnel is proposed. A RA is defined and its main characteristics are described. Methods of RA prevention are proposed, as is a plan of specific measures to deal with RA in accordance with the proposed classification

  10. The Chernobyl accident consequences

    International Nuclear Information System (INIS)

    2001-04-01

    Five teen years later, Tchernobyl remains the symbol of the greater industrial nuclear accident. To take stock on this accident, this paper proposes a chronology of the events and presents the opinion of many international and national organizations. It provides also web sites references concerning the environmental and sanitary consequences of the Tchernobyl accident, the economic actions and propositions for the nuclear safety improvement in the East Europe. (A.L.B.)

  11. 49 CFR 195.50 - Reporting accidents.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Reporting accidents. 195.50 Section 195.50 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Annual, Accident, and Safety-Related Condition Reporting § 195.50 Reporting accidents. An accident...

  12. 28 CFR 301.106 - Repetitious accidents.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Repetitious accidents. 301.106 Section 301.106 Judicial Administration FEDERAL PRISON INDUSTRIES, INC., DEPARTMENT OF JUSTICE INMATE ACCIDENT COMPENSATION General § 301.106 Repetitious accidents. If an inmate worker is involved in successive accidents...

  13. Accident management on french PWRS

    International Nuclear Information System (INIS)

    Queniart, D.

    1990-06-01

    After a brief recall of French safety rationale, the reactor operation and severe accident management is given. The research and development aimed at developing accident management procedures and emergency organization in France for the case of a NPP accident are also given

  14. Overview of core disruptive accidents

    International Nuclear Information System (INIS)

    Marchaterre, J.F.

    1977-01-01

    An overview of the analysis of core-disruptive accidents is given. These analyses are for the purpose of understanding and predicting fast reactor behavior in severe low probability accident conditions, to establish the consequences of such conditions and to provide a basis for evaluating consequence limiting design features. The methods are used to analyze core-disruptive accidents from initiating event to complete core disruption, the effects of the accident on reactor structures and the resulting radiological consequences are described

  15. Safety assessment for a potential SNF repository and its implication to the proliferation resistance nuclear fuel cycle

    International Nuclear Information System (INIS)

    Hwang, Y.; Jeong, M.S.; Seo, C.S.

    2007-01-01

    KAERI is developing the pyro-process technology to minimize the burden on permanent disposal of spent nuclear fuel. In addition, KAERI has developed the Korean Reference System for potential spent nuclear fuel disposal since 1997. The deep geologic disposal system is composed of a multi-barrier system in a crystalline rock to dispose of 36,000 MT of spent nuclear fuel (SNF) from a CANDU and a PWR. Quite recently, introduction of advanced nuclear fuel cycles such as pyro-processing is a big issue to solve the everlasting disposal problem and to assure the sustainable supply of fuel for reactors. To compare the effect of direct disposal of SNF with that of the high level waste disposal for waste generated from the advanced nuclear fuel cycles, the total system performance assessment for two different schemes is developed; one for direct disposal of SNF and the other for the introduction of the pyro-processing and direct disposal CANDU spent nuclear fuel. The safety indicators to assess the environmental friendliness of the disposal option are annual individual doses, toxicities and risks. Even though many scientists use the toxicity to understand the environmental friendliness of the disposal, scientifically the annual individual doses or risks are meaningful indicators for it. The major mechanisms to determine the doses and risks for direct disposal are as follows: (1) Dissolution mechanisms of uranium dioxides which control the dissolution of most nuclides such as TRU's and most parts of fission products. (2) Instant release fraction of highly soluble nuclides such as I-129, C-135, Tc-99, and others. (3) Retardation and dilution effect of natural and engineered barriers. (4) Dilution effect in the biosphere. The dominant nuclide is I-129 which follows both congruent and instantaneous release modes. Since its long half life associated with the instantaneous release I-129 is dominant well beyond one million. The impact of the TRU's is negligible until the significant

  16. Wireless Roadside Inspection Phase II Tennessee Commercial Mobile Radio Services Pilot Test Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Franzese, Oscar [ORNL; Lascurain, Mary Beth [ORNL; Capps, Gary J [ORNL; Siekmann, Adam [ORNL

    2011-05-01

    The Federal Motor Carrier Safety Administration (FMCSA) Wireless Roadside Inspection (WRI) Program is researching the feasibility and value of electronically assessing truck and bus driver and vehicle safety at least 25 times more often than is possible using only roadside physical inspections. The WRI program is evaluating the potential benefits to both the motor carrier industry and to government. These potential benefits include reduction in accidents, fatalities and injuries on our highways and keeping safe and legal drivers and vehicles moving on the highways. WRI Pilot tests were conducted to prototype, test and demonstrate the feasibility and benefits of electronically collecting safety data message sets from in-service commercial vehicles and performing wireless roadside inspections using three different communication methods. This report summarizes the design, conduct and results of the Tennessee CMRS WRI Pilot Test. The purpose of this Pilot test was to demonstrate the implementation of commercial mobile radio services to electronically request and collect safety data message sets from a limited number of commercial vehicles operating in Tennessee. The results of this test have been used in conjunction with the results of the complimentary pilot tests to support an overall assessment of the feasibility and benefits of WRI in enhancing motor carrier safety (reduction in accidents) due to increased compliance (change in motor carrier and driver behavior) caused by conducting frequent safety inspections electronically, at highway speeds, without delay or need to divert into a weigh station

  17. Traffic Accidents on Slippery Roads

    DEFF Research Database (Denmark)

    Fonnesbech, J. K.; Bolet, Lars

    2014-01-01

    Police registrations from 65 accidents on slippery roads in normally Danish winters have been studied. The study showed: • 1 accident per 100 km when using brine spread with nozzles • 2 accidents per 100 km when using pre wetted salt • 3 accidents per 100 km when using kombi spreaders The results...... of accidents in normally Danish winter seasons are remarkable alike the amount of salt used in praxis in the winter 2011/2012. • 2.7 ton NaCl/km when using brine spread with nozzles • 5 ton NaCl/km when using pre wetted salt. • 5.7 ton NaCl/km when using kombi spreaders The explanation is that spreading...

  18. 32 CFR 644.532 - Reporting accidents.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Reporting accidents. 644.532 Section 644.532... and Improvements § 644.532 Reporting accidents. Immediately upon receipt of information of an accident... that an accident has occurred, the former using command should be requested to send qualified explosive...

  19. Accidents with sulfuric acid

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2006-01-01

    Full Text Available Sulfuric acid is an important industrial and strategic raw material, the production of which is developing on all continents, in many factories in the world and with an annual production of over 160 million tons. On the other hand, the production, transport and usage are very dangerous and demand measures of precaution because the consequences could be catastrophic, and not only at the local level where the accident would happen. Accidents that have been publicly recorded during the last eighteen years (from 1988 till the beginning of 2006 are analyzed in this paper. It is very alarming data that, according to all the recorded accidents, over 1.6 million tons of sulfuric acid were exuded. Although water transport is the safest (only 16.38% of the total amount of accidents in that way 98.88% of the total amount of sulfuric acid was exuded into the environment. Human factor was the common factor in all the accidents, whether there was enough control of the production process, of reservoirs or transportation tanks or the transport was done by inadequate (old tanks, or the accidents arose from human factor (inadequate speed, lock of caution etc. The fact is that huge energy, sacrifice and courage were involved in the recovery from accidents where rescue teams and fire brigades showed great courage to prevent real environmental catastrophes and very often they lost their lives during the events. So, the phrase that sulfuric acid is a real "environmental bomb" has become clearer.

  20. Accidents in nuclear ships

    Energy Technology Data Exchange (ETDEWEB)

    Oelgaard, P L [Risoe National Lab., Roskilde (Denmark); [Technical Univ. of Denmark, Lyngby (Denmark)

    1996-12-01

    This report starts with a discussion of the types of nuclear vessels accidents, in particular accidents which involve the nuclear propulsion systems. Next available information on 61 reported nuclear ship events in considered. Of these 6 deals with U.S. ships, 54 with USSR ships and 1 with a French ship. The ships are in almost all cases nuclear submarines. Only events that involve the sinking of vessels, the nuclear propulsion plants, radiation exposures, fires/explosions, sea-water leaks into the submarines and sinking of vessels are considered. For each event a summary of available information is presented, and comments are added. In some cases the available information is not credible, and these events are neglected. This reduces the number of events to 5 U.S. events, 35 USSR/Russian events and 1 French event. A comparison is made between the reported Soviet accidents and information available on dumped and damaged Soviet naval reactors. It seems possible to obtain good correlation between the two types of events. An analysis is made of the accident and estimates are made of the accident probabilities which are found to be of the order of 10{sup -3} per ship reactor years. It if finally pointed out that the consequences of nuclear ship accidents are fairly local and does in no way not approach the magnitude of the Chernobyl accident. It is emphasized that some of the information on which this report is based, may not be correct. Consequently some of the results of the assessments made may not be correct. (au).

  1. Accidents in nuclear ships

    International Nuclear Information System (INIS)

    Oelgaard, P.L.

    1996-12-01

    This report starts with a discussion of the types of nuclear vessels accidents, in particular accidents which involve the nuclear propulsion systems. Next available information on 61 reported nuclear ship events in considered. Of these 6 deals with U.S. ships, 54 with USSR ships and 1 with a French ship. The ships are in almost all cases nuclear submarines. Only events that involve the sinking of vessels, the nuclear propulsion plants, radiation exposures, fires/explosions, sea-water leaks into the submarines and sinking of vessels are considered. For each event a summary of available information is presented, and comments are added. In some cases the available information is not credible, and these events are neglected. This reduces the number of events to 5 U.S. events, 35 USSR/Russian events and 1 French event. A comparison is made between the reported Soviet accidents and information available on dumped and damaged Soviet naval reactors. It seems possible to obtain good correlation between the two types of events. An analysis is made of the accident and estimates are made of the accident probabilities which are found to be of the order of 10 -3 per ship reactor years. It if finally pointed out that the consequences of nuclear ship accidents are fairly local and does in no way not approach the magnitude of the Chernobyl accident. It is emphasized that some of the information on which this report is based, may not be correct. Consequently some of the results of the assessments made may not be correct. (au)

  2. Contributing factors in construction accidents.

    Science.gov (United States)

    Haslam, R A; Hide, S A; Gibb, A G F; Gyi, D E; Pavitt, T; Atkinson, S; Duff, A R

    2005-07-01

    This overview paper draws together findings from previous focus group research and studies of 100 individual construction accidents. Pursuing issues raised by the focus groups, the accident studies collected qualitative information on the circumstances of each incident and the causal influences involved. Site based data collection entailed interviews with accident-involved personnel and their supervisor or manager, inspection of the accident location, and review of appropriate documentation. Relevant issues from the site investigations were then followed up with off-site stakeholders, including designers, manufacturers and suppliers. Levels of involvement of key factors in the accidents were: problems arising from workers or the work team (70% of accidents), workplace issues (49%), shortcomings with equipment (including PPE) (56%), problems with suitability and condition of materials (27%), and deficiencies with risk management (84%). Employing an ergonomics systems approach, a model is proposed, indicating the manner in which originating managerial, design and cultural factors shape the circumstances found in the work place, giving rise to the acts and conditions which, in turn, lead to accidents. It is argued that attention to the originating influences will be necessary for sustained improvement in construction safety to be achieved.

  3. Consequences of the Chernobyl reactor accident with respect to the feeding of infants

    International Nuclear Information System (INIS)

    Schmidt, E.

    1987-01-01

    In view of the persisting and understandable fear of parents with regard to radioactivity in the food of their babies as a consequence of the Chernobyl reactor accident, the Commission on Nutrition of the Deutsche Gesellschaft fuer Kinderheilkunde (German Society of Pediatrics) and the Strahlenschutzkommission have published a statement. According to this statement, the maximum permissible level of radioactivity in commercial baby food has been fixed by the EC to be 370 Bq/kg. The dietetic food industry itself has fixed a maximum for its products which is only a tenth of the radioactivity level permitted by the EC directive. The milk powders for infants tested since the reactor accident contained no measurable radioactivity or only very low amounts of Cs 134 or Cs 137, correspondung to a maximum of 25 Bq/kg in the product. Late damage to health is not to be expected. (orig./ECB) [de

  4. The SWI/SNF BAF-A complex is essential for neural crest development.

    Science.gov (United States)

    Chandler, Ronald L; Magnuson, Terry

    2016-03-01

    Growing evidence indicates that chromatin remodeler mutations underlie the pathogenesis of human neurocristopathies or disorders that affect neural crest cells (NCCs). However, causal relationships among chromatin remodeler subunit mutations and NCC defects remain poorly understood. Here we show that homozygous loss of ARID1A-containing, SWI/SNF chromatin remodeling complexes (BAF-A) in NCCs results in embryonic lethality in mice, with mutant embryos succumbing to heart defects. Strikingly, monoallelic loss of ARID1A in NCCs led to craniofacial defects in adult mice, including shortened snouts and low set ears, and these defects were more pronounced following homozygous loss of ARID1A, with the ventral cranial bones being greatly reduced in size. Early NCC specification and expression of the BRG1 NCC target gene, PLEXINA2, occurred normally in the absence of ARID1A. Nonetheless, mutant embryos displayed incomplete conotruncal septation of the cardiac outflow tract and defects in the posterior pharyngeal arteries, culminating in persistent truncus arteriosus and agenesis of the ductus arteriosus. Consistent with this, migrating cardiac NCCs underwent apoptosis within the circumpharyngeal ridge. Our data support the notion that multiple, distinct chromatin remodeling complexes govern genetically separable events in NCC development and highlight a potential pathogenic role for NCCs in the human BAF complex disorder, Coffin-Siris Syndrome. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Radiological accidents: education for prevention and confrontation

    International Nuclear Information System (INIS)

    Cardenas Herrera, Juan; Fernandez Gomez, Isis Maria

    2008-01-01

    The purpose of this work is to train and inform on radiological accidents as a preventive measure to improve the people life quality. Radiological accidents are part of the events of technological origin which are composed of nuclear and radiological accidents. As a notable figure is determined that there have been 423 radiological accidents from 1944 to 2005 and among the causes prevail industrial accidents, by irradiations, medical accidents and of laboratories, among others. Latin American countries such as Argentina, Brazil, Mexico and Peru are some where most accidents have occurred by radioactivity. The radiological accidents can have sociological, environmental, economic, social and political consequences. In addition, there are scenarios of potential nuclear accidents and in them the potential human consequences. Also, the importance of the organization and planning in a nuclear emergency is highlighted. Finally, the experience that Cuba has lived on the subject of radiological accidents is described [es

  6. Human Factors Engineering and Ergonomics Analysis for the Canister Storage Building (CSB) Results and Findings

    Energy Technology Data Exchange (ETDEWEB)

    GARVIN, L.J.

    1999-09-20

    The purpose for this supplemental report is to follow-up and update the information in SNF-3907, Human Factors Engineering (HFE) Analysis: Results and Findings. This supplemental report responds to applicable U.S. Department of Energy Safety Analysis Report review team comments and questions. This Human Factors Engineering and Ergonomics (HFE/Erg) analysis was conducted from April 1999 to July 1999; SNF-3907 was based on analyses accomplished in October 1998. The HFE/Erg findings presented in this report and SNF-3907, along with the results of HNF-3553, Spent Nuclear Fuel Project, Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report,'' Chapter A3.0, ''Hazards and Accidents Analyses,'' provide the technical basis for preparing or updating HNF-3553. Annex A, Chaptex A13.0, ''Human Factors Engineering.'' The findings presented in this report allow the HNF-3553 Chapter 13.0, ''Human Factors,'' to respond fully to the HFE requirements established in DOE Order 5480.23, Nuclear Safety Analysis Reports.

  7. The use of CAFE-3D for the simulation of tunnel fires

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, C.; Koski, J.A.; Hohnstreiter, G.F.; Khalil, I. [Sandia National Labs., Albuquerque, NM (United States); Suo-Anttila, A. [Alion Science and Technology, Albuquerque, NM (United States)

    2004-07-01

    Fires after accidents inside tunnels, such as the July 2001 Howard Street Tunnel fire in Baltimore, Maryland, USA, have raised stakeholder questions concerning the survivability of a spent nuclear fuel (SNF) transport cask when exposed to similar thermal environments. The analysis of tunnel fires is a computational challenge because of the need for very large computational domains in order to fully simulate such a problem. In this paper, the analyses of two different tunnel fire scenarios are described and the performance of typical SNF casks when exposed to these tunnel fire environments is discussed. The CAFE-3D fire code is used to model a series of fires inside tunnels, and the thermal performance of a SNF transportation cask within such fire environments is estimated with the use of the MSC PATRAN-P/Thermal finite element analysis code. The methodology used to simulate this type of fire scenario as well as a description of the manner in which the CAFE code couples the computational fluid dynamics and the finite element analysis techniques are also presented.

  8. The use of CAFE-3D for the simulation of tunnel fires

    International Nuclear Information System (INIS)

    Lopez, C.; Koski, J.A.; Hohnstreiter, G.F.; Khalil, I.; Suo-Anttila, A.

    2004-01-01

    Fires after accidents inside tunnels, such as the July 2001 Howard Street Tunnel fire in Baltimore, Maryland, USA, have raised stakeholder questions concerning the survivability of a spent nuclear fuel (SNF) transport cask when exposed to similar thermal environments. The analysis of tunnel fires is a computational challenge because of the need for very large computational domains in order to fully simulate such a problem. In this paper, the analyses of two different tunnel fire scenarios are described and the performance of typical SNF casks when exposed to these tunnel fire environments is discussed. The CAFE-3D fire code is used to model a series of fires inside tunnels, and the thermal performance of a SNF transportation cask within such fire environments is estimated with the use of the MSC PATRAN-P/Thermal finite element analysis code. The methodology used to simulate this type of fire scenario as well as a description of the manner in which the CAFE code couples the computational fluid dynamics and the finite element analysis techniques are also presented

  9. Urban risks of truck transport of radioactive material

    International Nuclear Information System (INIS)

    Mills, G.S.; Neuhauser, K.S.

    1998-01-01

    Truck transport of radioactive material (RAM), e.g., spent nuclear fuel (SNF), normally maximizes use of Interstate highways, which are safer and more efficient for truck transport in general. In the estimation of transportation risks, population bordering a route is a direct factor in determining consequences and an indirect factor in determining exposure times, accident probabilities and severities, and other parameters. Proposals to transport RAM may draw intense resistance from stakeholders based on concern for population concentrations along urban segments but the length of a route segment is also a determinative factor in estimating the transport risks. To quantify the relative importance of these two factors, a potential route for transport of SNF (strict use of Interstate highways) was selected and compared with a modified version that bypassed urban areas. The RADTRAN 4 code for transportation risk assessment, which was developed at Sandia National Laboratories, was used in the present study to assess the relative risks of SNF transportation for alternative routes. The results suggest that emphasis on Interstate highways minimizes total route and urban segment risks

  10. Transfer of radioactive contamination from milk to commercial dairy products

    International Nuclear Information System (INIS)

    Wilson, L.G.; Sutton, P.M.

    1988-01-01

    The fate of radioactive contamination resulting from fallout from the Chernobyl accident was studied during milk processing. A range of commercial dairy products was produced on a pilot-laboratory scale and the radiocaesium contents were measured by high-resolution gamma spectrometry. The results show that the radiocaesium partitioned with the water phase and therefore butter, cream and cheese had relatively low levels of radioactivity. Ion exchange demineralization was effective in removing radiocaesium from whey. Ultrafiltration of whey resulted in a reduction of radioactivity relative to retentate solids. (author)

  11. Postulated accident conditions for air cleaning systems and radiological dose assessments for containment options

    International Nuclear Information System (INIS)

    Hilliard, R.K.; Postma, A.K.

    1975-01-01

    Ambient conditions and performance requirements for emergency air cleaning systems applicable to commercial LMFBR plants were studied. The focus of this study centered on aerosol removal under hypothetical core disruptive accident conditions. Effort completed includes a review of air cleaning systems related to LMFBR plants, selection of three reference containment system designs, postulation of the EACS design basis accident (EACS-DBA), analysis of thermal conditions resulting from the DBA, analysis of aerosol transport behavior following the DBA, and an estimate of bone dose at the site boundary for each of the reference plant designs. Reference plant concepts were a single containment system (e.g., FFTF), a double containment system (e.g., CRBRP with closed head compartment), and a containment-confinement design in which an inerted, sealed primary volume was located within a ventilated building whose exhaust was filtered. The reference design basis accident selected here involved release to the inner containment system of 1 percent of non-volatile solids and plutonium, 25 percent of core halogens, 25 percent of core volatile solids, 100 percent of core noble gases, 68 lbs of sodium vapor and 5000 lbs of liquid sodium. 13 references. (U.S.)

  12. 22 CFR 102.8 - Reporting accidents.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Reporting accidents. 102.8 Section 102.8... Accidents Abroad § 102.8 Reporting accidents. (a) To airline and Civil Aeronautics Administration... probably be the first to be informed of the accident, in which event he will be expected to report the...

  13. First international workshop on severe accidents and their consequences. [Chernobyl Accident

    Energy Technology Data Exchange (ETDEWEB)

    1989-07-01

    An international workshop on past severe nuclear accidents and their consequences was held in Dagomys region of Sochi, USSR on October 30--November 3, 1989. The plan of this meeting was approved by the USSR Academy of Sciences and by the USSR State Committee of the Utilization of Atomic Energy. The meeting was held under the umbrella of the ANS-SNS agreement of cooperation. Topics covered include analysis of the Chernobyl accident, safety measures for RBMK type reactors and consequences of the Chernobyl accident including analysis of the ecological, genetic and psycho-social factors. Separate reports are processed separately for the data bases. (CBS)

  14. Guidance on accidents involving radioactivity

    International Nuclear Information System (INIS)

    1989-01-01

    This annex contains advice to Health Authorities on their response to accidents involving radioactivity. The guidance is in six parts:-(1) planning the response required to nuclear accidents overseas, (2) planning the response required to UK nuclear accidents a) emergency plans for nuclear installations b) nuclear powered satellites, (3) the handling of casualties contaminated with radioactive substances, (4) background information for dealing with queries from the public in the event of an accident, (5) the national arrangements for incident involving radioactivity (NAIR), (6) administrative arrangements. (author)

  15. ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation

    Directory of Open Access Journals (Sweden)

    Yuko Atsumi

    2015-12-01

    Full Text Available In response to DNA double-strand breaks (DSBs, H2AX is rapidly phosphorylated at Ser139 to promote DSB repair. Here we show that H2AX is rapidly stabilized in response to DSBs to efficiently generate γH2AX foci. This mechanism operated even in quiescent cells that barely expressed H2AX. H2AX stabilization resulted from the inhibition of proteasome-mediated degradation. Synthesized H2AX ordinarily underwent degradation through poly-ubiquitination mediated by the E3 ligase HUWE1; however, H2AX ubiquitination was transiently halted upon DSB formation. Such rapid H2AX stabilization by DSBs was associated with chromatin incorporation of H2AX and halting of its poly-ubiquitination mediated by the ATM kinase, the sirtuin protein SIRT6, and the chromatin remodeler SNF2H. H2AX Ser139, the ATM phosphorylation site, was essential for H2AX stabilization upon DSB formation. Our results reveal a pathway controlled by ATM, SIRT6, and SNF2H to block HUWE1, which stabilizes H2AX and induces its incorporation into chromatin only when cells are damaged.

  16. Review of severe accidents and the results of accident consequence assessment in different energy systems (Contract research)

    International Nuclear Information System (INIS)

    Matsuki, Yoshio; Muramatsu, Ken

    2008-05-01

    The cases of severe accidents and the consequence assessments in different energy systems, Coal, Oil, Gas, Hydro and Nuclear, were collected, and then they were further analyzed. In this report, the information on the accidents in various energy systems were collected from the sources of the Paul Scherrer Institute (hereinafter, 'PSI') and the International Atomic Energy Agency (hereinafter, 'IAEA'). The information on the severe accidents of nuclear power plants were collected from the report of the US Presidential Commission on Catastrophic Nuclear Accidents and several relevant reports issued in the countries of the European Union, together with the reports of the PSI and the IAEA. To analyze the collected information, several parameters, which are numbers of fatalities, injuries, evacuees and the costs of the damages, were chosen to characterize those accidents in different energy systems. And then, upon the comparison of these characteristics of different accidents, the impacts of the accidents in nuclear and other energy systems were compared. Upon the results of the analysis, it is pointed out that the cost caused by the Chernobyl Accident, the severe accident in nuclear energy, tends to be higher than in the other energy systems. On the other hand, from the aspects of fatalities and injuries, it is not confirmed that the damages of the Chernobyl Accident are larger than in the other energy systems. However, it is also recognized, as the specific characteristics of the severe nuclear accident, that the impacts of the accident spread in a wider area, and stay for a longer period, in comparison with the ones in the other energy systems. (author)

  17. The epidemiology of bicyclist's collision accidents

    DEFF Research Database (Denmark)

    Larsen, L. B.

    1994-01-01

    of bicyclists and risk situations. The findings should make a basis for preventive programmes in order to decrease the number and severity of bicyclists collision accidents. Data from the emergency room in a 2 year period was combined with data from questionnaires. The study group consisted of 1021 bicyclists......The number of bicyclists injured in the road traffic in collision accidents and treated at the emergency room at Odense University Hospital has increased 66% from 1980 to 1989. The aim of this study was to examine the epidemiology of bicyclist's collision accidents and identify risk groups...... injured in collision accidents, and 1502 bicyclists injured in single accidents was used as a reference group. The young bicyclists 10-19 years of age had the highest incidence of injuries caused by collision accidents. The collision accidents had different characteristics according to counterpart. One...

  18. International aspects of nuclear accidents

    International Nuclear Information System (INIS)

    Uematsu, K.

    1989-09-01

    The accident at Chernobyl revealed that there were shortcomings and gaps in the existing international mechanisms and brought home to governments the need for stronger measures to provide better protection against the risks of severe accidents. The main thrust of international co-operation with regard to nuclear safety issues is aimed at achieving a uniformly high level of safety in nuclear power plants through continuous exchanges of research findings and feedback from reactor operating experience. The second type of problem posed in the event of an accident resulting in radioactive contamination of several countries relates to the obligation to notify details of the circumstances and nature of the accident speedily so that the countries affected can take appropriate protective measures and, if necessary, organize mutual assistance. Giving the public accurate information is also an important aspect of managing an emergency situation arising from a severe accident. Finally, the confusion resulting from the unwarranted variety of protective measures implemented after the Chernobyl accident has highlighted the need for international harmonization of the principles and scientific criteria applicable to the protection of the public in the event of an accident and for a more consistent approach to emergency plans. The international conventions on third party liability in the nuclear energy sector (Paris/Brussels Conventions and the Vienna Convention) provide for compensation for damage caused by nuclear accidents in accordance with the rules and jurisdiction that they lay down. These provisions impose obligations on the operator responsible for an accident, and the State where the nuclear facility is located, towards the victims of damage caused in another country

  19. Computerized accident management support system: development for severe accident management

    International Nuclear Information System (INIS)

    Garcia, V.; Saiz, J.; Gomez, C.

    1998-01-01

    The activities involved in the international Halden Reactor Project (HRP), sponsored by the OECD, include the development of a Computerized Accident Management Support System (CAMS). The system was initially designed for its operation under normal conditions, operational transients and non severe accidents. Its purpose is to detect the plant status, analyzing the future evolution of the sequence (initially using the APROS simulation code) and the possible recovery and mitigation actions in case of an accident occurs. In order to widen the scope of CAMS to severe accident management issues, the integration of the MAAP code in the system has been proposed, as the contribution of the Spanish Electrical Sector to the project (with the coordination of DTN). To include this new capacity in CAMS is necessary to modify the system structure, including two new modules (Diagnosis and Adjustment). These modules are being developed currently for Pressurized Water Reactors and Boiling Water REactors, by the engineering of UNION FENOSA and IBERDROLA companies (respectively). This motion presents the characteristics of the new structure of the CAMS, as well as the general characteristics of the modules, developed by these companies in the framework of the Halden Reactor Project. (Author)

  20. Containment severe accident thermohydraulic phenomena

    International Nuclear Information System (INIS)

    Frid, W.

    1991-08-01

    This report describes and discusses the containment accident progression and the important severe accident containment thermohydraulic phenomena. The overall objective of the report is to provide a rather detailed presentation of the present status of phenomenological knowledge, including an account of relevant experimental investigations and to discuss, to some extent, the modelling approach used in the MAAP 3.0 computer code. The MAAP code has been used in Sweden as the main tool in the analysis of severe accidents. The dependence of the containment accident progression and containment phenomena on the initial conditions, which in turn are heavily dependent on the in-vessel accident progression and phenomena as well as associated uncertainties, is emphasized. The report is in three parts dealing with: * Swedish reactor containments, the severe accident mitigation programme in Sweden and containment accident progression in Swedish PWRs and BWRs as predicted by the MAAP 3.0 code. * Key non-energetic ex-vessel phenomena (melt fragmentation in water, melt quenching and coolability, core-concrete interaction and high temperature in containment). * Early containment threats due to energetic events (hydrogen combustion, high pressure melt ejection and direct containment heating, and ex-vessel steam explosions). The report concludes that our understanding of the containment severe accident progression and phenomena has improved very significantly over the parts ten years and, thereby, our ability to assess containment threats, to quantify uncertainties, and to interpret the results of experiments and computer code calculations have also increased. (au)

  1. Expert software for accident identification

    International Nuclear Information System (INIS)

    Dobnikar, M.; Nemec, T.; Muehleisen, A.

    2003-01-01

    Each type of an accident in a Nuclear Power Plant (NPP) causes immediately after the start of the accident variations of physical parameters that are typical for that type of the accident thus enabling its identification. Examples of these parameter are: decrease of reactor coolant system pressure, increase of radiation level in the containment, increase of pressure in the containment. An expert software enabling a fast preliminary identification of the type of the accident in Krsko NPP has been developed. As input data selected typical parameters from Emergency Response Data System (ERDS) of the Krsko NPP are used. Based on these parameters the expert software identifies the type of the accident and also provides the user with appropriate references (past analyses and other documentation of such an accident). The expert software is to be used as a support tool by an expert team that forms in case of an emergency at Slovenian Nuclear Safety Administration (SNSA) with the task to determine the cause of the accident, its most probable scenario and the source term. The expert software should provide initial identification of the event, while the final one is still to be made after appropriate assessment of the event by the expert group considering possibility of non-typical events, multiple causes, initial conditions, influences of operators' actions etc. The expert software can be also used as an educational/training tool and even as a simple database of available accident analyses. (author)

  2. Big nuclear accidents

    International Nuclear Information System (INIS)

    Marshall, W.

    1983-01-01

    Much of the debate on the safety of nuclear power focuses on the large number of fatalities that could, in theory, be caused by extremely unlikely but imaginable reactor accidents. This, along with the nuclear industry's inappropriate use of vocabulary during public debate, has given the general public a distorted impression of the safety of nuclear power. The way in which the probability and consequences of big nuclear accidents have been presented in the past is reviewed and recommendations for the future are made including the presentation of the long-term consequences of such accidents in terms of 'reduction in life expectancy', 'increased chance of fatal cancer' and the equivalent pattern of compulsory cigarette smoking. (author)

  3. Process criticality accident likelihoods, magnitudes and emergency planning. A focus on solution accidents

    International Nuclear Information System (INIS)

    McLaughlin, Thomas P.

    2003-01-01

    This paper presents analyses and applications of data from reactor and critical experiment research on the dynamics of nuclear excursions in solution media. Available criticality accident information is also discussed and shown to provide strong evidence of the overwhelming likelihood of accidents in liquid media over other forms and to support the measured data. These analyses are shown to provide valuable insights into key parameters important to understanding solution excursion dynamics in general and in evaluating practical upper bounds on criticality accident magnitudes. This understanding and these upper bounds are directly applicable to the evaluation of the consequences of postulated criticality accidents. These bounds are also essential in order to comply with national and international consensus standards and regulatory requirements for emergency planning. (author)

  4. Accidents in family forestry's firewood production.

    Science.gov (United States)

    Lindroos, Ola; Aspman, Emma Wilhelmson; Lidestav, Gun; Neely, Gregory

    2008-05-01

    Firewood is commonly used around the world, but little is known about the work involved in its production and associated accidents. The objectives were to identify relationships between accidents and time exposure, workers' age and sex, equipment used and work activities in family forestry's firewood production. Data from a postal survey in Northern Sweden were compared to a database of injuries in the same region. Most accidents occurred to 50-69 year old men, who also worked most hours. No significant differences in sex and age were found between expected and recorded accident frequencies when calculated from total work hours; however, when calculated using numbers of active persons significant differences were found for both age and sex. Frequency of accidents per unit worked time was higher for machine involving activities than for other activities. Accidents that occurred when using wedge splitter machines were responsible for most of this overrepresentation. Fingers were the most commonly injured body parts. Mean accident rate for the equipment used was 87 accidents per million work hours, and the rate was highest for wedge splitters (122 accidents per million work hours). Exposure to elevated risks due to violation of safety procedures is discussed, as well as possible preventative measures.

  5. [Accidents on Iceland's most dangerous roads].

    Science.gov (United States)

    Bjarnason, Thóroddur; Arnarsson, Sveinn

    2012-02-01

    The objective of this paper was to identify the most dangerous segments of the Icelandic road system in terms of the number of accidents pr km and the rate of accidents pr million km travelled. First to identify the segments where the number of accidents is highest and where the risk of the individual traveller is the greatest. Second to evaluate if the association between the number and the rate of accidents is positive or negative. Third to identify the road segments that are the most dangerous in the sense of many accidents and great risk to individual travellers. Main roads outside urban centers were divided into 45 segments that were on average 78 km in length. Infrequently travelled roads and roads within urban centers were omitted. Information on the length of roads, traffic density and number of accidents was used to calculate the number of accidents per km and the rate of accidents per million km travelled. The correlation between the number and rate of accidents was calculated and the most dangerous road segments were identified by the average rank order on both dimensions. Most accidents pr km occurred on the main roads to and from the capital region, but also east towards Hvolsvöllur, north towards Akureyri and in the Mideast region of the country. The rate of accidents pr million km travelled was highest in the northeast region, in northern Snæfellsnes and in the Westfjords. The most dangerous roads on both dimensions were in Mideast, northern Westfjords, in the north between Blönduós and Akureyri and in northern Snæfellsnes. Most accidents pr km occurred on roads with a low accident rate pr million km travelled. It is therefore possible to reduce accidents the most by increasing road safety where it is already the greatest but that would however increase inequalities in road safety. Policy development in transportation is therefore in part a question of priorities in healthcare. Individual equality in safety and health are not always fully

  6. Improving Accident Tolerance of Nuclear Fuel with Coated Mo-alloy Cladding

    Directory of Open Access Journals (Sweden)

    Bo Cheng

    2016-02-01

    Full Text Available In severe loss of coolant accidents (LOCA, similar to those experienced at Fukushima Daiichi and Three Mile Island Unit 1, the zirconium alloy fuel cladding materials are rapidly heated due to nuclear decay heating and rapid exothermic oxidation of zirconium with steam. This heating causes the cladding to rapidly react with steam, lose strength, burst or collapse, and generate large quantities of hydrogen gas. Although maintaining core cooling remains the highest priority in accident management, an accident tolerant fuel (ATF design may extend coping and recovery time for operators to restore emergency power, and cooling, and achieve safe shutdown. An ATF is required to possess high resistance to steam oxidation to reduce hydrogen generation and sufficient mechanical strength to maintain fuel rod integrity and core coolability. The initiative undertaken by Electric Power Research Institute (EPRI is to demonstrate the feasibility of developing an ATF cladding with capability to maintain its integrity in 1,200–1,500°C steam for at least 24 hours. This ATF cladding utilizes thin-walled Mo-alloys coated with oxidation-resistant surface layers. The basic design consists of a thin-walled Mo alloy structural tube with a metallurgically bonded, oxidation-resistant outer layer. Two options are being investigated: a commercially available iron, chromium, and aluminum alloy with excellent high temperature oxidation resistance, and a Zr alloy with demonstrated corrosion resistance. As these composite claddings will incorporate either no Zr, or thin Zr outer layers, hydrogen generation under severe LOCA conditions will be greatly reduced. Key technical challenges and uncertainties specific to Mo alloy fuel cladding include: economic core design, industrial scale fabricability, radiation embrittlement, and corrosion and oxidation resistance during normal operation, transients, and severe accidents. Progress in each aspect has been made and key results are

  7. Report on a radiotherapy underdose accident

    Energy Technology Data Exchange (ETDEWEB)

    Christodoulides, G; Christofides, S [Medical Physics Department, Nicosia General Hospital, 1450 Nicosia (Cyprus)

    1999-12-31

    Reporting information on accidents and incidents involving radiation sources provides a body of knowledge which can help to prevent accidents of a similar nature. Accident information has to be made available to users, manufacturers and regulators; An international effort to pool and analyse incident and accident information will provide more complete and reliable indicators of root causes and trends and recommendations for future accident avoidance. An accident due to human error involving a superficial x-ray therapy machine and patients treated for postoperative breast cancer is reported here. 43 women receiving radiotherapy treatment have received significantly less radiation dose than the prescribed dose. The worst dose percentage within the radiation field was 20% of the prescribed dose. The worst dose percentage on the operation scar of the breast was 52% of the prescribed radiation dose. The response to accidents/incidents in radiotherapy is discussed. (authors) 4 refs., 5 figs., 1 tabs.

  8. Strategy generation in accident management support

    International Nuclear Information System (INIS)

    Sirola, M.

    1995-01-01

    An increased interest for research in the field of Accident Management can be noted. Several international programmes have been started in order to be able to understand the basic physical and chemical phenomena in accident conditions. A feasibility study has shown that it would be possible to design and develop a computerized support system for plant staff in accident situations. To achieve this goal the Halden Project has initiated a research programme on Computerized Accident Management Support (CAMS project). The aim is to utilize the capabilities of computerized tools to support the plant staff during the various accident stages. The system will include identification of the accident state, assessment of the future development of the accident and planning of accident mitigation strategies. A prototype is developed to support operators and the Technical Support Centre in decision making during serious accident in nuclear power plants. A rule based system has been built to take care of the strategy generation. This system assists plant personnel in planning control proposals and mitigation strategies from normal operation to severe accident conditions. The ideal of a safety objective tree and knowledge from the emergency procedures have been used. Future prediction requires good state identification of the plant status and some knowledge about the history of some critical variables. The information needs to be validated as well. Accurate calculations in simulators and a large database including all important information form the plant will help the strategy planning. (author). 12 refs, 2 figs

  9. Thyroid diseases after Chernobyl accident

    International Nuclear Information System (INIS)

    Nagataki, Shigenobu

    1993-01-01

    Radioactive iodine is released at every atomic-bomb testings and nuclear plants accidents and radioactive iodine is taken up by thyroid glands (internal radiation). In addition to the internal radiation, radioactive fallout causes the external radiation and thyroid glands are known to be sensitive to the external radiation. Furthermore, patients with radiation-induced thyroid disease can survive for a long time regardless of the treatment. The survey of thyroid diseases, therefore, is very sensitive and reliable ways to investigate the effects of radiation caused by atomic bomb explosion, testing and various types of nuclear plants' accidents. Our group from Nagasaki University was asked to investigate the thyroid diseases and jointed to the Sasakawa Project. In order to investigate the effects of radiation on thyroid disease, it is essential 1) to make a correct diagnosis in each subject, 2) to calculate a correct radiation dose in each subject and finally, 3) to find out the correlation between the radiation dose and thyroid diseases including age-, sex- and area-matched controls. We have established 5 centers (1 in Russia, 2 in Belarus, 2 in Ukraine) and supplied the most valuable ultrasonography instruments, commercial kits for the determination of serum free T 4 and TSH level and for the autoantibodies, instrument for urinary iodine measurements, syringers, tubes, refrigerators, etc. We visit each center often and asked people at centers to come to Japan for training. Protocol of investigation is essentially the same as that in Nagasaki, and we are planning to investigate more than 50,000 children within 5 years. We are hoping to show a definite conclusion in the near future. Recent articles are also discussed. (author)

  10. Psychological and social impacts of post-accident situations: lessons from the Chernobyl accident

    International Nuclear Information System (INIS)

    Lochard, J.

    1996-01-01

    This paper presents the main features, from the psychological and social points of view, of the post-accident situation in the contaminated areas around Chernobyl. This is based on a series of surveys performed in the concerned territories of the CIS republics. The high level of stress affecting a large segment of the population is related to the perception of the situation by those living in a durably contaminated environment but also to the side-effects of some of the countermeasures adopted to mitigate the radiological consequences or to compensate the affected population. The distinction between the accident and the post-accident phase is enlarged to take into account the various phases characterizing the dynamics of the social response. Although the size of the catastrophe as well as the economic and political conditions that were prevailing at the time and after the accident have resulted in a maximal intensity of the reactions of the population, many lessons can be drawn for the management of potential post-accident situations. (author)

  11. Severe Accident Research Program plan update

    International Nuclear Information System (INIS)

    1992-12-01

    In August 1989, the staff published NUREG-1365, ''Revised Severe Accident Research Program Plan.'' Since 1989, significant progress has been made in severe accident research to warrant an update to NUREG-1365. The staff has prepared this SARP Plan Update to: (1) Identify those issues that have been closed or are near completion, (2) Describe the progress in our understanding of important severe accident phenomena, (3) Define the long-term research that is directed at improving our understanding of severe accident phenomena and developing improved methods for assessing core melt progression, direct containment heating, and fuel-coolant interactions, and (4) Reflect the growing emphasis in two additional areas--advanced light water reactors, and support for the assessment of criteria for containment performance during severe accidents. The report describes recent major accomplishments in understanding the underlying phenomena that can occur during a severe accident. These include Mark I liner failure, severe accident scaling methodology, source term issues, core-concrete interactions, hydrogen transport and combustion, TMI-2 Vessel Investigation Project, and direct containment heating. The report also describes the major planned activities under the SARP over the next several years. These activities will focus on two phenomenological issues (core melt progression, and fuel-coolant interactions and debris coolability) that have significant uncertainties that impact our understanding and ability to predict severe accident phenomena and their effect on containment performance SARP will also focus on severe accident code development, assessment and validation. As the staff completes the research on severe accident issues that relate to current generation reactors, continued research will focus on efforts to independently evaluate the capability of new advanced light water reactor designs to withstand severe accidents

  12. JCO criticality accident termination operation

    International Nuclear Information System (INIS)

    Kanamori, Masashi

    2001-12-01

    On September 30 at around 10:35 AM, criticality accident occurred at the JCO's conversion building in Tokai-mura. Since criticality accident had not been anticipated, neither devices for termination of criticality accident nor neutron detectors were available. Immediately after the information of the accident, our emergency staff (Japan Nuclear Cycle development institute staff) went to JCO site, to measure the intensity of neutrons and gammas. There were four main tasks, first one was to measure the radiation intensity, second one was to terminate the criticality accident, third one is to alert the residents surrounding the JCO site, fourth one is to evacuate the employees in the site. These tasks were successfully performed until October 1. This paper describes about how these operations were performed by the relevant staffs. (author)

  13. Approach to accident management in RBMK-1500

    International Nuclear Information System (INIS)

    Kaliatka, A.; Urbonavicius, E.; Uspuras, E.

    2008-01-01

    In order to ensure the safe operation of the nuclear power plants accident management programs are being developed around the world. These accident management programs cover the whole spectrum of accidents, including severe accidents. A lot of work is done to investigate the severe accident phenomena and implement severe accident management in NPPs with vessel-type reactors, while less attention is paid to channel-type reactors CANDU and RBMK. Ignalina NPP with RBMK-1500 reactor has implemented symptom based emergency operation procedures, which cover management of accidents until the core damage and do not extend to core damage region. In order to ensure coverage of the whole spectrum of accidents and meet the requirements of IAEA the severe accident management guidelines have to be developed. This paper presents the basic principles and approach to management of beyond design basis accidents at Ignalina NPP. In general, this approach could be applied to NPPs with RBMK-1000 reactors that are available in Russia, but the design differences should be taken into account

  14. Use of bayesian operations for diagnosing accidents

    International Nuclear Information System (INIS)

    Kang, K.M.; Jae, M.; Suh, K.Y.

    2005-01-01

    In complex systems, it is necessary to model a logical representation of the overall system interaction with respect to the individual subsystems. Operators are allowed to follow EOPs (Emergency Operating Procedures) when reactor tripped because of accidents. But, it's very difficult to diagnose accidents and find out appropriate procedures to mitigate current accidents in a given short time. Even if they diagnose accidents, it also has possibility to misdiagnose. TMI accident is a good example of operators' errors. Methodology using Influence Diagrams has been developed and applied for representing the dependency behaviors and uncertain behaviors of complex systems. An example to diagnose the accidents such as SLOCA and SGTR with similar symptoms has been introduced. From the constructed model, operators could diagnose accidents at any states of accidents. This model can offer the information about accidents with given symptoms. This model might help operators to diagnose correctly and rapidly. It might be very useful to support operators to reduce human error. Also, from this study, it is applicable to diagnose other accidents with similar symptoms and to analyze causes of reactor trip. (authors)

  15. CARNSORE: Hypothetical reactor accident study

    International Nuclear Information System (INIS)

    Walmod-Larsen, O.; Jensen, N.O.; Kristensen, L.; Meide, A.; Nedergaard, K.L.; Nielsen, F.; Lundtang Petersen, E.; Petersen, T.; Thykier-Nielsen, S.

    1984-06-01

    Two types of design-basis accident and a series of hypothetical core-melt accidents to a 600 MWe reactor are described and their consequences assessed. The PLUCON 2 model was used to calculate the consequences which are presented in terms of individual and collective doses, as well as early and late health consequences. The site proposed for the nucelar power station is Carnsore Point, County Wexford, south-east Ireland. The release fractions for the accidents described are those given in WASH-1400. The analyses are based on the resident population as given in the 1979 census and on 20 years of data from the meteorological stations at Rosslare Harbour, 8.5 km north of the site. The consequences of one of the hypothetical core-melt accidents are described in detail in a meteorological parametric study. Likewise the consequences of the worst conceivable combination of situations are described. Finally, the release fraction in one accident is varied and the consequences of a proposed, more probable ''Class 9 accident'' are presented. (author)

  16. Learning from nuclear accident experience

    International Nuclear Information System (INIS)

    Vaurio, J.K.

    1984-01-01

    Statistical procedures are developed to estimate accident occurrence rates from historical event records, to predict future rates and trends, and to estimate the accuracy of the rate estimates and predictions. Maximum likelihood estimation is applied to several learning models, and results are compared to earlier graphical and analytical estimates. The models are based on (1) the cumulative number of operating years, (2) the cumulative number of plants built, and (3) accidents (explicitly), with the accident rate distinctly different before and after an accident. The statistical accuracies of the parameters estimated are obtained in analytical form using the Fisher information matrix. Using data on core damage accidents in electricity producing plants, it is estimated that the probability for a plant to have a serious flaw has decreased from 0.1 to 0.01 during the developmental phase of the nuclear industry. At the same time the equivalent frequency of accidents has decreased from 0.04 per reactor year to 0.0004 per reactor year, partly due to the increasing population of plants. 10 references, 7 figures, 2 tables

  17. [Occupational noise exposure and work accidents].

    Science.gov (United States)

    Dias, Adriano; Cordeiro, Ricardo; Gonçalves, Cláudia Giglio de Oliveira

    2006-10-01

    The purpose of this study was to verify whether occupational noise exposure is a significant risk factor for work accidents in the city of Piracicaba, São Paulo State, Brazil. This hospital-based case-control study included 600 workers aged 15-60 who suffered typical occupational accidents between May and October 2004 and were seen at the Piracicaba Orthopedics and Trauma Center. The control group comprised 822 workers, aged 15-60, who were also seen at the Center, and either had a non-occupational accident or were accompanying someone who had suffered an accident. A multiple logistic regression model was adjusted with work accident as an independent variable, controlled by covariables of interest such as noise exposure. The risk of having a work accident was about twice as high among workers exposed to noise, after controlling for several covariables. Occupational noise exposure not only affected auditory health status but was also a risk factor for work accidents.

  18. Management of accident risks

    International Nuclear Information System (INIS)

    Compes, P.C.

    1987-01-01

    The example of the Chernobyl accident and the statistics of the occurrence of accidents make clear the threat to humanity, if one cannot guarantee successful accident prevention in the use and distribution of the projects aimed at. The science of safety, as it is known in the Wuppertal model, makes its contribution to this vital task for the human community. It makes it necessary to create the essential dates and concepts, the methods, principles and techniques based on them and the associated instrumentation. (DG) [de

  19. Mortality among a cohort of U.S. commercial airline cockpit crew.

    Science.gov (United States)

    Yong, Lee C; Pinkerton, Lynne E; Yiin, James H; Anderson, Jeri L; Deddens, James A

    2014-08-01

    We evaluated mortality among 5,964 former U.S. commercial cockpit crew (pilots and flight engineers). The outcomes of a priori interest were non-chronic lymphocytic leukemia, central nervous system (CNS) cancer (including brain), and malignant melanoma. Vital status was ascertained through 2008. Life table and Cox regression analyses were conducted. Cumulative exposure to cosmic radiation was estimated from work history data. Compared to the U.S. general population, mortality from all causes, all cancer, and cardiovascular diseases was decreased, but mortality from aircraft accidents was highly elevated. Mortality was elevated for malignant melanoma but not for non-chronic lymphocytic leukemia. CNS cancer mortality increased with an increase in cumulative radiation dose. Cockpit crew had a low all-cause, all-cancer, and cardiovascular disease mortality but elevated aircraft accident mortality. Further studies are needed to clarify the risk of CNS and other radiation-associated cancers in relation to cosmic radiation and other workplace exposures. © 2014 Wiley Periodicals, Inc.

  20. EPRI research on accident management

    International Nuclear Information System (INIS)

    Oehlberg, R.N.; Chao, J.

    1991-01-01

    The paper discusses Nuclear Regulatory Commission (NRC) efforts regarding severe reactor accident management and the Nuclear Management and Resources Council (NUMAEX), activities. (EPRI) Electric Power Research Institute accident management program consists of the two products just mentioned plus one related to severe accident plant status information and the MAAP 4.0 computer code. These are briefly discussed