WorldWideScience

Sample records for commercial dissemination approaches

  1. Lessons learned about art-based approaches for disseminating knowledge.

    Science.gov (United States)

    Bruce, Anne; Makaroff, Kara L Schick; Sheilds, Laurene; Beuthin, Rosanne; Molzahn, Anita; Shermak, Sheryl

    2013-01-01

    To present a case example of using an arts-based approach and the development of an art exhibit to disseminate research findings from a narrative research study. Once a study has been completed, the final step of dissemination of findings is crucial. In this paper, we explore the benefits of bringing nursing research into public spaces using an arts-based approach. Findings from a qualitative narrative study exploring experiences of living with life-threatening illnesses. Semi-structured in-depth interviews were conducted with 32 participants living with cancer, chronic renal disease, or HIV/AIDS. Participants were invited to share a symbol representing their experience of living with life-threatening illness and the meaning it held for them. The exhibit conveyed experiences of how people story and re-story their lives when living with chronic kidney disease, cancer or HIV. Photographic images of symbolic representations of study participants' experiences and poetic narratives from their stories were exhibited in a public art gallery. The theoretical underpinning of arts-based approaches and the lessons learned in creating an art exhibit from research findings are explored. Creative art forms for research and disseminating knowledge offer new ways of understanding and knowing that are under-used in nursing. Arts-based approaches make visible patients' experiences that are often left unarticulated or hidden. Creative dissemination approaches such as art exhibits can promote insight and new ways of knowing that communicate nursing research to both public and professional audiences.

  2. Assessing approaches for dissemination of research information to ...

    African Journals Online (AJOL)

    Mo

    index. Abstract. This study sought to, identify and describe the approaches used by research and service providers in technology dissemination ... Farmers preferred this method of training but called for more of, trainings, availability of improved seed ... for the NAADS program and department of agriculture were purposively ...

  3. Lead farmers approach in disseminating improved tef production ...

    African Journals Online (AJOL)

    Lead farmers approach in disseminating improved tef production technologies. ... The results of the analysis showed that eight of the lead farmers were very satisfied with the new variety. High grain yield was obtained at the 10 on-farm sites due to the introduction of new variety. While the grain yields ranged from 0.7 and 2.9 ...

  4. NASA's approach to space commercialization

    Science.gov (United States)

    Gillam, Isaac T., IV

    1986-01-01

    The NASA Office of Commercial Programs fosters private participation in commercially oriented space projects. Five Centers for the Commercial Development of Space encourage new ideas and perform research which may yield commercial processes and products for space ventures. Joint agreements allow companies who present ideas to NASA and provide flight hardware access to a free launch and return from orbit. The experimenters furnish NASA with sufficient data to demonstrate the significance of the results. Ground-based tests are arranged for smaller companies to test the feasibility of concepts before committing to the costs of developing hardware. Joint studies of mutual interest are performed by NASA and private sector researchers, and two companies have signed agreements for a series of flights in which launch costs are stretched out to meet projected income. Although Shuttle flights went on hold following the Challenger disaster, extensive work continues on the preparation of commercial research payloads that will fly when Shuttle flights resume.

  5. A Community-Aware Approach to Minimizing Dissemination in Graphs

    KAUST Repository

    Zhang, Chuxu

    2017-08-02

    Given a graph, can we minimize the spread of an entity (such as a meme or a virus) while maintaining the graph’s community structure (defined as groups of nodes with denser intra-connectivity than inter-connectivity)? At first glance, these two objectives seem at odds with each other. To minimize dissemination, nodes or links are often deleted to reduce the graph’s connectivity. These deletions can (and often do) destroy the graph’s community structure, which is an important construct in real-world settings (e.g., communities promote trust among their members). We utilize rewiring of links to achieve both objectives. Examples of rewiring in real life are prevalent, such as purchasing products from a new farm since the local farm has signs of mad cow disease; getting information from a new source after a disaster since your usual source is no longer available, etc. Our community-aware approach, called constrCRlink (short for Constraint Community Relink), preserves (on average) 98.6% of the efficacy of the best community-agnostic link-deletion approach (namely, NetMelt+), but changes the original community structure of the graph by only 4.5%. In contrast, NetMelt+ changes 13.6% of the original community structure.

  6. Music Confucius Institute: Evaluating Its Approach as an Agent for International Chinese Music Dissemination

    Science.gov (United States)

    Guo, Wei; Li, Sheng Bing

    2016-01-01

    The paper identifies the educational and presentational functions of the Confucius Institute (MCI) at the Royal Danish Academy of Music (RDAM) as its core approaches which mostly influence Chinese cultural dissemination in its host country. The MCI's utilization of the two dissemination approaches aligns with the "receiver-centered"…

  7. Approaches to Mixed Methods Dissemination and Implementation Research: Methods, Strengths, Caveats, and Opportunities.

    Science.gov (United States)

    Green, Carla A; Duan, Naihua; Gibbons, Robert D; Hoagwood, Kimberly E; Palinkas, Lawrence A; Wisdom, Jennifer P

    2015-09-01

    Limited translation of research into practice has prompted study of diffusion and implementation, and development of effective methods of encouraging adoption, dissemination and implementation. Mixed methods techniques offer approaches for assessing and addressing processes affecting implementation of evidence-based interventions. We describe common mixed methods approaches used in dissemination and implementation research, discuss strengths and limitations of mixed methods approaches to data collection, and suggest promising methods not yet widely used in implementation research. We review qualitative, quantitative, and hybrid approaches to mixed methods dissemination and implementation studies, and describe methods for integrating multiple methods to increase depth of understanding while improving reliability and validity of findings.

  8. A convergent diffusion and social marketing approach for disseminating proven approaches to physical activity promotion.

    Science.gov (United States)

    Dearing, James W; Maibach, Edward W; Buller, David B

    2006-10-01

    Approaches from diffusion of innovations and social marketing are used here to propose efficient means to promote and enhance the dissemination of evidence-based physical activity programs. While both approaches have traditionally been conceptualized as top-down, center-to-periphery, centralized efforts at social change, their operational methods have usually differed. The operational methods of diffusion theory have a strong relational emphasis, while the operational methods of social marketing have a strong transactional emphasis. Here, we argue for a convergence of diffusion of innovation and social marketing principles to stimulate the efficient dissemination of proven-effective programs. In general terms, we are encouraging a focus on societal sectors as a logical and efficient means for enhancing the impact of dissemination efforts. This requires an understanding of complex organizations and the functional roles played by different individuals in such organizations. In specific terms, ten principles are provided for working effectively within societal sectors and enhancing user involvement in the processes of adoption and implementation.

  9. The TIPS Evaluation Project: A Theory-Driven Approach to Dissemination Research.

    Science.gov (United States)

    Mulvey, Kevin P.; Hayashi, Susan W.; Hubbard, Susan M.; Kopstien, Andrea; Huang, Judy Y.

    2003-01-01

    Introduces the special section that focuses on four major studies under the treatment improvement protocols (TIPs) evaluation project. Provides an overview of each article, and addresses the value of using a theory-driven approach to dissemination research. (SLD)

  10. Private Appropriation, Public Dissemination and Commercial Product Development in Genomics (DOE)

    Energy Technology Data Exchange (ETDEWEB)

    Rebecca S. Eisenberg

    2003-03-19

    With DOE funding, I have conducted research on the topic of patents and technology transfer in the Human Genome Project since 1994. My research has proceeded along the following tracks: (1) research and monitoring of legal developments relating to (a) the patenting of DNA sequences and (b) the role of patents in technology transfer; (2) investigating and monitoring the strategies of different institutions in the public and private sector that are involved in DNA sequencing with respect to patenting and disseminating sequence information; (3) investigating and monitoring the impact of these strategies on those who use sequence information in research and product development. I have published commentary as my research proceeds in a variety of forums directed at scientists, lawyers, and science policy-makers.

  11. An approach to drought data web-dissemination

    Science.gov (United States)

    Angeluccetti, Irene; Perez, Francesca; Balbo, Simone; Cámaro, Walther; Boccardo, Piero

    2017-04-01

    Drought data dissemination has always been a challenge for the scientific community. Firstly, a variety of widely known datasets is currently being used to describe different aspects of this same phenomenon. Secondly, new indexes are constantly being produced by scientists trying to better capture drought events. The present work aims at presenting how the drought monitoring communication issue was addressed by the ITHACA team. The ITHACA drought monitoring system makes use of two indicators: the Standardized Precipitation Index (SPI) and the Seasonal Small Integral Deviation (SSID). The first one is obtained considering the 3-months cumulating interval of the rainfall derived from the TRMM dataset; the second one is the percent deviation from the historical average value of the integral of the NDVI function describing the vegetation season. The SPI and the SSID are 30 and 5 km gridded respectively. The whole time-series of these two indicators (since year 2000 onwards), covering the whole Africa, are published by a WebGIS platform (http://drought.ithacaweb.org). On the one hand, although the SPI has been used for decades in different contexts and little explanation is due when presenting this indicator to an audience with a scientific background, the WebGIS platform shows a guide for its correct interpretation. On the other hand, being the SSID not commonly used in the field of vegetation analysis, the guide shown on the WebGIS platform is essential for the visitor to understand the data. Recently a new index has been created in order to synthesize, for a non-expert audience, the information provided by the indicators. It is aggregated per second order administrative levels and is calculated as follows: (i) a meteorological drought warning is issued when negative SPI and no vegetative season is detected (a blue palette is used); (ii) a warning value is assigned if SSID, SPI, or both, are negative (amber to brown palette is used) i.e., where the vegetative season

  12. Evolutionary Game Analysis of Competitive Information Dissemination on Social Networks: An Agent-Based Computational Approach

    Directory of Open Access Journals (Sweden)

    Qing Sun

    2015-01-01

    Full Text Available Social networks are formed by individuals, in which personalities, utility functions, and interaction rules are made as close to reality as possible. Taking the competitive product-related information as a case, we proposed a game-theoretic model for competitive information dissemination in social networks. The model is presented to explain how human factors impact competitive information dissemination which is described as the dynamic of a coordination game and players’ payoff is defined by a utility function. Then we design a computational system that integrates the agent, the evolutionary game, and the social network. The approach can help to visualize the evolution of % of competitive information adoption and diffusion, grasp the dynamic evolution features in information adoption game over time, and explore microlevel interactions among users in different network structure under various scenarios. We discuss several scenarios to analyze the influence of several factors on the dissemination of competitive information, ranging from personality of individuals to structure of networks.

  13. A hazard-independent approach for the standardised multi-channel dissemination of warning messages

    Science.gov (United States)

    Esbri Palomares, M. A.; Hammitzsch, M.; Lendholt, M.

    2012-04-01

    The tsunami disaster affecting the Indian Ocean region on Christmas 2004 demonstrated very clearly the shortcomings in tsunami detection, public warning processes as well as intergovernmental warning message exchange in the Indian Ocean region. In that regard, early warning systems require that the dissemination of early warning messages has to be executed in way that ensures that the message delivery is timely; the message content is understandable, usable and accurate. To that end, diverse and multiple dissemination channels must be used to increase the chance of the messages reaching all affected persons in a hazard scenario. In addition to this, usage of internationally accepted standards for the warning dissemination such as the Common Alerting Protocol (CAP) and Emergency Data Exchange Language (EDXL) Distribution Element specified by the Organization for the Advancement of Structured Information Standards (OASIS) increase the interoperability among different warning systems enabling thus the concept of system-of-systems proposed by GEOSS. The project Distant Early Warning System (DEWS), co-funded by the European Commission under the 6th Framework Programme, aims at strengthening the early warning capacities by building an innovative generation of interoperable tsunami early warning systems based on the above mentioned concepts following a Service-oriented Architecture (SOA) approach. The project focuses on the downstream part of the hazard information processing where customized, user-tailored warning messages and alerts flow from the warning centre to the responsible authorities and/or the public with their different needs and responsibilities. The information logistics services within DEWS generate tailored EDXL-DE/CAP warning messages for each user that must receive the message according to their preferences, e.g., settings for language, interested areas, dissemination channels, etc.. However, the significant difference in the implementation and

  14. Dissemination of a theory-based online bone health program: Two intervention approaches.

    Science.gov (United States)

    Nahm, Eun-Shim; Resnick, Barbara; Bellantoni, Michele; Zhu, Shijun; Brown, Clayton; Brennan, Patricia F; Charters, Kathleen; Brown, Jeanine; Rietschel, Matthew; Pinna, Joanne; An, Minjeong; Park, Bu Kyung; Plummer, Lisa

    2015-06-01

    With the increasing nationwide emphasis on eHealth, there has been a rapid growth in the use of the Internet to deliver health promotion interventions. Although there has been a great deal of research in this field, little information is available regarding the methodologies to develop and implement effective online interventions. This article describes two social cognitive theory-based online health behavior interventions used in a large-scale dissemination study (N = 866), their implementation processes, and the lessons learned during the implementation processes. The two interventions were a short-term (8-week) intensive online Bone Power program and a longer term (12-month) Bone Power Plus program, including the Bone Power program followed by a 10-month online booster intervention (biweekly eHealth newsletters). This study used a small-group approach (32 intervention groups), and to effectively manage those groups, an eLearning management program was used as an upper layer of the Web intervention. Both interventions were implemented successfully with high retention rates (80.7% at 18 months). The theory-based approaches and the online infrastructure used in this study showed a promising potential as an effective platform for online behavior studies. Further replication studies with different samples and settings are needed to validate the utility of this intervention structure. © The Author(s) 2013.

  15. Getting the Word Out: New Approaches for Disseminating Public Health Science.

    Science.gov (United States)

    Brownson, Ross C; Eyler, Amy A; Harris, Jenine K; Moore, Justin B; Tabak, Rachel G

    The gap between discovery of public health knowledge and application in practice settings and policy development is due in part to ineffective dissemination. This article describes (1) lessons related to dissemination from related disciplines (eg, communication, agriculture, social marketing, political science), (2) current practices among researchers, (3) key audience characteristics, (4) available tools for dissemination, and (5) measures of impact. Dissemination efforts need to take into account the message, source, audience, and channel. Practitioners and policy makers can be more effectively reached via news media, social media, issue or policy briefs, one-on-one meetings, and workshops and seminars. Numerous "upstream" and "midstream" indicators of impact include changes in public perception or awareness, greater use of evidence-based interventions, and changes in policy. By employing ideas outlined in this article, scientific discoveries are more likely to be applied in public health agencies and policy-making bodies.

  16. Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak.

    Science.gov (United States)

    Bogoch, Isaac I; Creatore, Maria I; Cetron, Martin S; Brownstein, John S; Pesik, Nicki; Miniota, Jennifer; Tam, Theresa; Hu, Wei; Nicolucci, Adriano; Ahmed, Saad; Yoon, James W; Berry, Isha; Hay, Simon I; Anema, Aranka; Tatem, Andrew J; MacFadden, Derek; German, Matthew; Khan, Kamran

    2015-01-03

    The WHO declared the 2014 west African Ebola epidemic a public health emergency of international concern in view of its potential for further international spread. Decision makers worldwide are in need of empirical data to inform and implement emergency response measures. Our aim was to assess the potential for Ebola virus to spread across international borders via commercial air travel and assess the relative efficiency of exit versus entry screening of travellers at commercial airports. We analysed International Air Transport Association data for worldwide flight schedules between Sept 1, 2014, and Dec 31, 2014, and historic traveller flight itinerary data from 2013 to describe expected global population movements via commercial air travel out of Guinea, Liberia, and Sierra Leone. Coupled with Ebola virus surveillance data, we modelled the expected number of internationally exported Ebola virus infections, the potential effect of air travel restrictions, and the efficiency of airport-based traveller screening at international ports of entry and exit. We deemed individuals initiating travel from any domestic or international airport within these three countries to have possible exposure to Ebola virus. We deemed all other travellers to have no significant risk of exposure to Ebola virus. Based on epidemic conditions and international flight restrictions to and from Guinea, Liberia, and Sierra Leone as of Sept 1, 2014 (reductions in passenger seats by 51% for Liberia, 66% for Guinea, and 85% for Sierra Leone), our model projects 2.8 travellers infected with Ebola virus departing the above three countries via commercial flights, on average, every month. 91,547 (64%) of all air travellers departing Guinea, Liberia, and Sierra Leone had expected destinations in low-income and lower-middle-income countries. Screening international travellers departing three airports would enable health assessments of all travellers at highest risk of exposure to Ebola virus infection

  17. Knowledge dissemination: a core mission

    CERN Multimedia

    2011-01-01

    It’s been a year since the CERN Council approved our policy on intellectual property management, so I’d like to take a look at what we’ve achieved since then. In short, a great deal. We’ve moved away from a fairly unregulated approach towards a well balanced and clearly defined system built around sound intellectual property management designed to deliver maximum dissemination and benefit for society from CERN innovation. It’s a move that I celebrate and fully support.   In 2009, CERN signed two partnership agreements to develop CERN technologies, two commercial licenses and eleven R&D licenses. Last year, the figures were six partnership agreements, five commercial licenses and twenty R&D licenses, indicating a real increase in dissemination efforts. From 2009 to 2010, however, the number of new technologies that were identified and disclosed hardly changed: nine in 2009, ten in 2010. These numbers are good, but we must improve, particu...

  18. Dissemination of sustainable irrigation strategies for almond and olive orchards via a participatory approach. Project LIFE+IRRIMAN

    Science.gov (United States)

    Garcia-Vila, Margarita; Gamero-Ojeda, Pablo; Ascension Carmona, Maria; Berlanga, Jose; Fereres, Elias

    2017-04-01

    Dissemination of sustainable irrigation strategies for almond and olive orchards via a participatory approach. Project LIFE+IRRIMAN Spain is the world's first and third largest producer of olive oil and almond, respectively. Despite huge efforts in the last years by the production sector towards intensification, cultural issues relative to the traditional rain-fed crop management know how, prevent farmers from adoption of sustainable irrigation management practices. Consequently, even though there has been progress in irrigation management research for these two crops, adoption of modern irrigation techniques by farmers has been slow. Sustainable irrigation strategies for olive and almond orchards are being designed, implemented, validated and disseminated under the framework of the LIFE+ IRRIMAN project, through a participatory approach. The implementation of the LIFE+ IRRIMAN innovative and demonstrative actions has been carried out in an irrigation district of Southern Spain (Genil-Cabra Irrigation Scheme, Andalusia). The approach designed has four phases: i) design and implementation of sustainable irrigation strategies in demonstration farms; ii) dissemination of best irrigation practices which were tested in the initial year throughout the irrigation scheme by the irrigation advisory service; iii) assessment of degree of adoption and re-design of the dissemination strategies; and, iv) based on the results obtained, elaboration of sustainable irrigation guidelines for knowledge transfer in the district at regional and national levels to promote changes in irrigation practices. Participatory approaches have proven to be effective tools for successful irrigation strategies design and diffusion, especially in traditional rain fed crops such as olive and almond trees in the Mediterranean countries. Acknowledgements This work has been funded by the European Union LIFE+ project IRRIMAN (LIFE13 ENV/ES/000539).

  19. New approach to reducing water consumption in commercial kitchen hood

    Science.gov (United States)

    Asmuin, N.; Pairan, M. R.

    2017-09-01

    Water mist sprays are used in wide range of application. However it is depend to the spray characteristic to suit the particular application. The modern commercial kitchen hood ventilation system was adopted with the water mist nozzle technology as an additional tool to increase the filtration efficiency. However, low level of filtration effectiveness and high water consumption were the major problems among the Commercial Kitchen Ventilation expert. Therefore, this study aims to develop a new mist spray technology to replacing the conventional KSJB nozzle (KSJB is a nozzle’s name). At the same time, an appropriate recommended location to install the nozzle in kitchen hood system was suggested. An extensive simulation works were carried out to observe the spray characteristics, ANSYS (FLUENT) was used for simulation wise. In the case of nozzle studies, nozzles were tested at 1 bar pressure of water and air. In comparison with conventional nozzles configuration, this new approach suggested nozzle configuration was reduce up to 50% of water consumption, which by adopted 3 numbers of nozzles instead of 6 numbers of nozzles in the commercial kitchen hood system. Therefore, this nozzle will be used in industry for their benefits of water consumption, filtration efficiency and reduced the safety limitations.

  20. A concept mapping approach to guide and understand dissemination and implementation.

    Science.gov (United States)

    Green, Amy E; Fettes, Danielle L; Aarons, Gregory A

    2012-10-01

    Many efforts to implement evidence-based programs do not reach their full potential or fail due to the variety of challenges inherent in dissemination and implementation. This article describes the use of concept mapping-a mixed method strategy-to study implementation of behavioral health innovations and evidence-based practice (EBP). The application of concept mapping to implementation research represents a practical and concise way to identify and quantify factors affecting implementation, develop conceptual models of implementation, target areas to address as part of implementation readiness and active implementation, and foster communication among stakeholders. Concept mapping is described and a case example is provided to illustrate its use in an implementation study. Implications for the use of concept mapping methods in both research and applied settings towards the dissemination and implementation of behavioral health services are discussed.

  1. Reaping the benefits of an open systems approach: getting the commercial approach right

    Science.gov (United States)

    Pearson, Gavin; Dawe, Tony; Stubbs, Peter; Worthington, Olwen

    2016-05-01

    Critical to reaping the benefits of an Open System Approach within Defence, or any other sector, is the ability to design the appropriate commercial model (or framework). This paper reports on the development and testing of a commercial strategy decision support tool. The tool set comprises a number of elements, including a process model, and provides business intelligence insights into likely supplier behaviour. The tool has been developed by subject matter experts and has been tested with a number of UK Defence procurement teams. The paper will present the commercial model framework, the elements of the toolset and the results of testing.

  2. Training scholars in dissemination and implementation research for cancer prevention and control: a mentored approach.

    Science.gov (United States)

    Padek, Margaret; Mir, Nageen; Jacob, Rebekah R; Chambers, David A; Dobbins, Maureen; Emmons, Karen M; Kerner, Jon; Kumanyika, Shiriki; Pfund, Christine; Proctor, Enola K; Stange, Kurt C; Brownson, Ross C

    2018-01-22

    As the field of D&I (dissemination and implementation) science grows to meet the need for more effective and timely applications of research findings in routine practice, the demand for formalized training programs has increased concurrently. The Mentored Training for Dissemination and Implementation Research in Cancer (MT-DIRC) Program aims to build capacity in the cancer control D&I research workforce, especially among early career researchers. This paper outlines the various components of the program and reports results of systematic evaluations to ascertain its effectiveness. Essential features of the program include selection of early career fellows or more experienced investigators with a focus relevant to cancer control transitioning to a D&I research focus, a 5-day intensive training institute, ongoing peer and senior mentoring, mentored planning and work on a D&I research proposal or project, limited pilot funding, and training and ongoing improvement activities for mentors. The core faculty and staff members of the MT-DIRC program gathered baseline and ongoing evaluation data regarding D&I skill acquisition and mentoring competency through participant surveys and analyzed it by iterative collective reflection. A majority (79%) of fellows are female, assistant professors (55%); 59% are in allied health disciplines, and 48% focus on cancer prevention research. Forty-three D&I research competencies were assessed; all improved from baseline to 6 and 18 months. These effects were apparent across beginner, intermediate, and advanced initial D&I competency levels and across the competency domains. Mentoring competency was rated very highly by the fellows--higher than rated by the mentors themselves. The importance of different mentoring activities, as rated by the fellows, was generally congruent with their satisfaction with the activities, with the exception of relatively greater satisfaction with the degree of emotional support and relatively lower

  3. A New Approach to Commercialization of NASA's Human Research Program Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Phase I SBIR proposal describes, "A New Approach to Commercialization of NASA's Human Research Program Technologies." NASA has a powerful research...

  4. [Disseminated strongyloidiasis].

    Science.gov (United States)

    Nozais, J P; Thellier, M; Datry, A; Danis, M

    2001-04-28

    ENDEMIC ZONES: Strongyloidiasis is an intestinal parasitosis which is frequently found in tropical and subtropical regions. RISK: The "autoinfection" cycle during this helminthiasis explains why the infection can be perpetuated without further exposure to exogenous, infective larvae. Hyperinfection may occur by dissemination of Strongyloides stercoralis in immuno-compromised patients, particularly those under corticotherapy. DISSEMINATATED STRONGYLOIDIASIS: Disseminated strongyloidiasis is characterized by severe gastrointestinal and respiratory tract involvement, meningitis, skin rash, or Gram-negative bacteremia. Since disseminated stronglyoidiasis is fatal in 80% of cases it is imperative to diagnose and treat this condition before long-term corticotherapy. Ivermectin is currently recommended because it is effective and well tolerated.

  5. Methodical Approaches to Risk Management in a Regional Commercial Bank

    Directory of Open Access Journals (Sweden)

    Elena Vladimirovna Altukhova

    2016-03-01

    Full Text Available The article presents the results of the research of the methodological and information infrastructure of the integrated risk management in a regional commercial bank. Within the study of the general development tendencies of the regional banking services market, the most significant risks for a regional bank are revealed. The analysis is carried out on the basis of the stress testing technique developed at the Plekhanov Russian University of Economics. It is based on a technique of dynamic economic and mathematical modeling with the application of information technologies. The created combination of the methodological and instrumental tools allows to carry out the dynamic scenario analysis of the activity of a commercial bank for the identification of potential risks and for the development of the strategy of financial management reducing the potential risks and leveling the consequences of their realization. The received tool allows during the computer test to watch the predicted dynamics of the condition of the key indicators of the activity of a regional commercial bank changing under the influence of the exogenous regulatory measures and instruments of bank management applied to decrease risk and at the same time to introduce adjustments in the perspective strategy of management. As the result of the analysis, the universal management model of the main bank risks in a regional commercial bank within three alternative scenarios is created. The software product allowing to develop and acquire the practical skills of the students in banking is developed. It also may help to develop the methodological support for the regulation of the organizational procedures of risk management in a regional commercial bank. The received software product may be used in a system of the improving the professional skills, and also for obtaining the expected data in a risk management system in a regional commercial bank.

  6. Accelerating Clean Energy Commercialization. A Strategic Partnership Approach

    Energy Technology Data Exchange (ETDEWEB)

    Adams, Richard [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pless, Jacquelyn [Joint Institute for Strategic Energy Analysis, Golden, CO (United States); Arent, Douglas J. [Joint Institute for Strategic Energy Analysis, Golden, CO (United States); Locklin, Ken [Impax Asset Management Group (United Kingdom)

    2016-04-01

    Technology development in the clean energy and broader clean tech space has proven to be challenging. Long-standing methods for advancing clean energy technologies from science to commercialization are best known for relatively slow, linear progression through research and development, demonstration, and deployment (RDD&D); and characterized by well-known valleys of death for financing. Investment returns expected by traditional venture capital investors have been difficult to achieve, particularly for hardware-centric innovations, and companies that are subject to project finance risks. Commercialization support from incubators and accelerators has helped address these challenges by offering more support services to start-ups; however, more effort is needed to fulfill the desired clean energy future. The emergence of new strategic investors and partners in recent years has opened up innovative opportunities for clean tech entrepreneurs, and novel commercialization models are emerging that involve new alliances among clean energy companies, RDD&D, support systems, and strategic customers. For instance, Wells Fargo and Company (WFC) and the National Renewable Energy Laboratory (NREL) have launched a new technology incubator that supports faster commercialization through a focus on technology development. The incubator combines strategic financing, technology and technical assistance, strategic customer site validation, and ongoing financial support.

  7. SOCIAL MARKETING APPROACH AS A TOOL FOR DISSEMINATION SPORT (FROM THE PERSPECTIVE OF SPORT FOR ALL)

    OpenAIRE

    Akyildiz, Muge

    2010-01-01

    Nowadays, organizations about “sport for all” and leisure sectors use marketing strategies and techniques to influence a target audience to voluntary participate in leisure activities. They should apply new marketing technologies and methods to endure in the developing and changing environment. One marketing strategy emphasizing the social welfare and health is social marketing. Social marketing is an application of marketing approaches from the business world to planning and management of so...

  8. Commercial Bee Pollen with Different Geographical Origins: A Comprehensive Approach

    Directory of Open Access Journals (Sweden)

    Leticia M. Estevinho

    2012-09-01

    Full Text Available Since the primordial of humanity, pollen has been considered a good source of nutrients and energy. Its promising healing properties have also been referred to. The present study aimed to characterize, for the first time, eight commercial pollens from Portugal and Spain available on the market studying the legislation on labeling, pollinic origin, physicochemical and microbiological analyses and identification of yeasts. Eleven botanical families were found amongst the samples. The most abundant family and the most dominant pollen was Cistaceae. The moisture content, ash, aw, pH, reducing sugars, carbohydrates, proteins, lipids and energy were analyzed and the specific parameters were within the specifications required by some countries with legislation regarding these parameters. Microbiologically commercial pollen showed acceptable safety for the commercial quality and hygiene. All samples showed negative results for toxigenic species. The microorganisms studied were aerobic mesophiles, yeasts and moulds, coliforms, Escherichia coli, Staphylococcus aureus, Salmonella and sulfite-reducing Clostridium. During the work, six yeasts species were isolated from pollen, with Rhodotorula mucilaginosa being the most abundant, as it was present in four samples.

  9. Commercial Bee Pollen with Different Geographical Origins: A Comprehensive Approach

    Science.gov (United States)

    Nogueira, Carla; Iglesias, Antonio; Feás, Xesus; Estevinho, Leticia M.

    2012-01-01

    Since the primordial of humanity, pollen has been considered a good source of nutrients and energy. Its promising healing properties have also been referred to. The present study aimed to characterize, for the first time, eight commercial pollens from Portugal and Spain available on the market studying the legislation on labeling, pollinic origin, physicochemical and microbiological analyses and identification of yeasts. Eleven botanical families were found amongst the samples. The most abundant family and the most dominant pollen was Cistaceae. The moisture content, ash, aw, pH, reducing sugars, carbohydrates, proteins, lipids and energy were analyzed and the specific parameters were within the specifications required by some countries with legislation regarding these parameters. Microbiologically commercial pollen showed acceptable safety for the commercial quality and hygiene. All samples showed negative results for toxigenic species. The microorganisms studied were aerobic mesophiles, yeasts and moulds, coliforms, Escherichia coli, Staphylococcus aureus, Salmonella and sulfite-reducing Clostridium. During the work, six yeasts species were isolated from pollen, with Rhodotorula mucilaginosa being the most abundant, as it was present in four samples. PMID:23109845

  10. A Culture-Centered Community-Grounded Approach to Disseminating Health Information among African Americans.

    Science.gov (United States)

    Dutta, Mohan J; Collins, William; Sastry, Shaunak; Dillard, Sydney; Anaele, Agaptus; Kumar, Rati; Roberson, Calvin; Robinson, Tracy; Bonu, Tafor

    2018-04-10

    This study highlights the role of local communities in creating culturally rooted health information resources based on comparative effectiveness research (CER), depicting the role of culture in creating entry points for building community-grounded communication structures for evidence-based health knowledge. We report the results from running a year-long culture-centered campaign that was carried out among African American communities in two counties, Lake and Marion County, in Indiana addressing basic evidence-based knowledge on four areas of cardiovascular disease (CVD). Campaign effectiveness was tested through an experimental design with post-test knowledge of CER among African Americans in these counties compared to CER knowledge among African Americans in a comparable control county (Allen). Our campaign, based on the principles of the culture-centered approach (CCA), increased community CER knowledge in the experimental communities relative to a community that did not receive the culturally centered health information campaign. The CCA-based campaign developed by community members and distributed through the mass media, community wide channels such as health fairs and church meetings, postcards, and face-to-face interventions explaining the postcards improved CER knowledge in specific areas (ACE-I/ARBs, atrial fibrillation, and renal artery stenosis) in the CCA communities as compared to the control community.

  11. GPM ground validation via commercial cellular networks: an exploratory approach

    Science.gov (United States)

    Rios Gaona, Manuel Felipe; Overeem, Aart; Leijnse, Hidde; Brasjen, Noud; Uijlenhoet, Remko

    2016-04-01

    The suitability of commercial microwave link networks for ground validation of GPM (Global Precipitation Measurement) data is evaluated here. Two state-of-the-art rainfall products are compared over the land surface of the Netherlands for a period of 7 months, i.e., rainfall maps from commercial cellular communication networks and Integrated Multi-satellite Retrievals for GPM (IMERG). Commercial microwave link networks are nowadays the core component in telecommunications worldwide. Rainfall rates can be retrieved from measurements of attenuation between transmitting and receiving antennas. If adequately set up, these networks enable rainfall monitoring tens of meters above the ground at high spatiotemporal resolutions (temporal sampling of seconds to tens of minutes, and spatial sampling of hundreds of meters to tens of kilometers). The GPM mission is the successor of TRMM (Tropical Rainfall Measurement Mission). For two years now, IMERG offers rainfall estimates across the globe (180°W - 180°E and 60°N - 60°S) at spatiotemporal resolutions of 0.1° x 0.1° every 30 min. These two data sets are compared against a Dutch gauge-adjusted radar data set, considered to be the ground truth given its accuracy, spatiotemporal resolution and availability. The suitability of microwave link networks in satellite rainfall evaluation is of special interest, given the independent character of this technique, its high spatiotemporal resolutions and availability. These are valuable assets for water management and modeling of floods, landslides, and weather extremes; especially in places where rain gauge networks are scarce or poorly maintained, or where weather radar networks are too expensive to acquire and/or maintain.

  12. A community-based approach to disseminate health information on the hazards of prenatal mercury exposure in Brooklyn, NY.

    Science.gov (United States)

    Callejo, Fay P; Geer, Laura A

    2012-08-01

    Exposure to mercury (Hg) in utero can have neurotoxic effects on the developing fetus. Mercury exposure in women of childbearing age has been associated with frequent fish consumption, coastal proximity, foreign birth, and exposure during ritualistic practices. The aim of this study was to identify culturally-appropriate strategies to disseminate messages on the hazards of in utero Hg exposure in fertile and pregnant women in a predominantly urban immigrant community in Flatbush, Brooklyn, following findings from a recent study on mercury exposure in this community. Nineteen key informant interviews were conducted in Flatbush, Brooklyn with community members, medical professionals, fishmongers, and a religious practitioner to solicit feedback on culturally sensitive methods to educate the community on Hg hazards. The main themes identified include clinical integration, where providers integrate the message in routine care; community integration, whereby influential organizations and community members foster message delivery; media usage; and message reinforcement via continuous exposure. It is vital for healthcare providers and public health practitioners to be culturally sensitive in educating their patients on fish selection during pregnancy and safety of handling Hg. Instead of a single approach, a combination of media and educational strategies would help to reinforce the message. These findings form a basis for public health campaigns to apprise other urban immigrant communities of the hazards of in utero Hg exposure.

  13. ARGE DFC - A European approach to MCFC commercialization

    Energy Technology Data Exchange (ETDEWEB)

    Kraus, P.; Huppmann, G. [MTU Friedrichshafen GmbH, Muenchen (Germany); Heiming, A. [Ruhgras AG, Dorsten (Germany)] [and others

    1996-12-31

    The largest European program for the commercialization of the molten carbonate fuel cell technology is carried out by the European Direct Fuel Cell Consortium (ARGE DFC). The consortium consists of the following companies: (1) MTU Friedrichshafen GmbH (Germany), within the DaimlerBenz Group responsible for off-road propulsion and decentralized energy systems. (2) Haldor Topsoe A/S (Denmark), a plant engineering company and specialist for catalytic processes (3) Elkraft A.m.b.A. (Denmark), one of the countries two utility companies (4) Ruhrgas AG (Germany), the largest German gas company (5) RWE AG (Germany), the largest German electrical utility company MTU acts as a consortium leader. The company shares a license and technology exchange agreement with Energy Research Corporation of Danbury, Connecticut.

  14. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

    Science.gov (United States)

    Becker, Sara J.

    2014-01-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed. PMID:25937710

  15. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions.

    Science.gov (United States)

    Becker, Sara J

    2015-03-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed.

  16. A New Approach to Commercialization of NASA's Human Research Program Technologies, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This Phase I SBIR proposal describes, "A New Approach to Commercialization of NASA's Human Research Program Technologies." NASA has a powerful research program that...

  17. SPATIAL SEARCH IN COMMERCIAL FISHING: A DISCRETE CHOICE DYNAMIC PROGRAMMING APPROACH

    OpenAIRE

    Smith, Martin D.; Provencher, Bill

    2003-01-01

    We specify a discrete choice dynamic programming model of commercial fishing participation and location choices. This approach allows us to examine how fishermen collect information about resource abundance and whether their behavior is forward-looking.

  18. Evaluation of a multi-methods approach to the collection and dissemination of feedback on OSCE performance in dental education.

    Science.gov (United States)

    Wardman, M J; Yorke, V C; Hallam, J L

    2017-05-19

    Feedback is an essential part of the learning process, and students expect their feedback to be personalised, meaningful and timely. Objective Structured Clinical Examination (OSCE) assessments allow examiners to observe students carefully over the course of a number of varied station types, across a number of clinical knowledge and skill domains. They therefore present an ideal opportunity to record detailed feedback which allows students to reflect on and improve their performance. This article outlines two methods by which OSCE feedback was collected and then disseminated to undergraduate dental students across 2-year groups in a UK dental school: (i) Individual written feedback comments made by examiners during the examination, (ii) General audio feedback recorded by groups of examiners immediately following the examination. Evaluation of the feedback was sought from students and staff examiners. A multi-methods approach utilising Likert questionnaire items (quantitative) and open-ended feedback questions (qualitative) was used. Data analysis explored student and staff perceptions of the audio and written feedback. A total of 131 students (response rate 68%) and 52 staff examiners (response rate 83%) completed questionnaires. Quantitative data analysis showed that the written and audio formats were reported as a meaningful source of feedback for learning by both students (93% written, 89% audio) and staff (96% written, 92% audio). Qualitative data revealed the complementary nature of both types of feedback. Written feedback gives specific, individual information whilst audio shares general observations and allows students to learn from others. The advantages, limitations and challenges of the feedback methods are discussed, leading to the development of an informed set of implementation guidelines. Written and audio feedback methods are valued by students and staff. It is proposed that these may be very easily applied to OSCEs running in other dental schools.

  19. Reducing eating disorder risk factors: a controlled investigation of a blended task-shifting/train-the-trainer approach to dissemination and implementation.

    Science.gov (United States)

    Kilpela, Lisa Smith; Hill, Kaitlin; Kelly, Mackenzie C; Elmquist, Joanna; Ottoson, Paige; Keith, Demetra; Hildebrandt, Thomas; Becker, Carolyn Black

    2014-12-01

    Recent advances in psychological intervention research have led to an increase in evidence-based interventions (EBIs), yet there remains a lag in dissemination and implementation of EBIs. Task-shifting and the train-the-trainer (TTT) model offer two potential strategies for enhancing reach of EBIs. The Body Project, an EBI found to prevent onset of eating disorders, served as the vehicle for this dissemination/implementation study. The primary aim of this study was to determine if training of peer-leaders for the Body Project could be task-shifted to undergraduate students using a hybrid task-shifting/TTT model. Our secondary aim was to determine if subgroups of participants evidenced different trajectories of change through 14-month follow-up. Regarding the first aim, we found almost no evidence to suggest that a presence of a doctoral-level trainer yielded superior participant outcomes compared to training by undergraduates alone. Regarding Aim 2, almost all classes for all variables evidenced improvement or a benign response. Additionally, for three key risk factors (thin-ideal internalization, body dissatisfaction, and ED symptoms) virtually all trajectories showed improvement. This study provides initial support for the use of a blended task-shifting/TTT approach to dissemination and implementation within prevention generally, and further support for broad dissemination of the Body Project specifically. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. NASA's human system risk management approach and its applicability to commercial spaceflight.

    Science.gov (United States)

    Law, Jennifer; Mathers, Charles H; Fondy, Susan R E; Vanderploeg, James M; Kerstman, Eric L

    2013-01-01

    As planning continues for commercial spaceflight, attention is turned to NASA to assess whether its human system risk management approach can be applied to mitigate the risks associated with commercial suborbital and orbital flights. NASA uses a variety of methods to assess the risks to the human system based on their likelihood and consequences. In this article, we review these methods and categorize the risks in the system as "definite," "possible," or "least" concern for commercial spaceflight. As with career astronauts, these risks will be primarily mitigated by screening and environmental control. Despite its focus on long-duration exploration missions, NASA's human system risk management approach can serve as a preliminary knowledge base to help medical planners prepare for commercial spaceflights.

  1. Engaging the small commercial sector: new approaches for solving market barriers

    International Nuclear Information System (INIS)

    Dandridge, Cyane; Walton, Jennifer; Bertoldi, Paolo

    2005-01-01

    This paper examines how effectively working with students and contractors can engage small commercial businesses in energy efficiency measures. Small commercial businesses are an underserved and hard-to-reach market for energy efficiency services. Yet, this sector comprises a significant percentage of all businesses and aggregate energy usage. Two main barriers to doing an energy retrofit in small businesses include getting the business to agree to participate and getting them to implement suggested measures. Student outreach addresses the first, and using a mechanical or electrical contractor as an ESCO is a great way to address the second. The Awareness for Community Energy (ACE) Program is currently being offered throughout the United States. ACE employs high school and college students as interns and trains them in small business energy auditing. The business more readily accepts the marketing of energy services by a student, since it is seen as an opportunity to contribute to a student's educational experience. In one case, ACE program participants audited over 150 small businesses in a three-month period. Electrical and mechanical contractors are prime candidates to both disseminate information on energy efficiency and carry out the necessary retrofits. The owners of most energy using facilities already have trusted mechanical/electrical service contractors. By diffusing ESCO concepts amongst existing service contractors, there is a far greater chance of upgrading the energy efficiency throughout the small business sector. Such diffusion activities will involve training and awareness programs for contractors, as well as encouragement of financial institutions to develop supportive financing products

  2. Effect of Various Inoculum Levels of Multidrug-Resistant Salmonella enterica Serovar Heidelberg (2011 Ground Turkey Outbreak Isolate on Cecal Colonization, Dissemination to Internal Organs, and Deposition in Skeletal Muscles of Commercial Turkeys after Experimental Oral Challenge

    Directory of Open Access Journals (Sweden)

    Divek V. T. Nair

    2018-01-01

    Full Text Available Salmonella enterica serovar Heidelberg (S. Heidelberg is a major foodborne pathogen colonizing poultry. The pathogen is associated with a significant number of foodborne outbreaks through contaminated poultry meat, including turkeys. Recently, multidrug-resistant (MDR strains of S. Heidelberg have emerged as a threat to human public health in the United States. The objective of this study was to determine the cecal colonization, dissemination to internal organs, and the potential for skeletal muscle deposition of an MDR S. Heidelberg isolate from the 2011 ground turkey outbreak in the United States after the experimental oral challenge of poults (young turkeys and adult turkey hens. In the poult study, two separate experiments using day-old, straight-run, commercial hybrid converter poults were randomly assigned to five challenge groups (0, 10∧2, 10∧4, 10∧6, 10∧8 CFU groups; 12 poults/group; N = 60/experiment and a week after, treatment groups were challenged separately with 0-, 2-, 4-, 6-, and 8- log10 CFU of S. Heidelberg orally. After 14 days post-challenge, the poults were euthanized, and samples were collected to determine MDR S. Heidelberg colonization in the cecum, dissemination to liver and spleen, and deposition in the thigh, drumstick, and breast muscles. A similar experimental design was followed for the adult turkey hens. In two separate experiments, 11-week-old commercial Hybrid Converter turkey hens (4 hens/group; N = 20/experiment were challenged with MDR S. Heidelberg and on day 16 post-challenge, birds were euthanized and samples were collected to determine Salmonella populations in the samples. The results indicated that, in turkey poults, the recovery of MDR S. Heidelberg was highest in the cecum followed by spleen, liver, thigh, drumstick, and breast. All tested inoculum levels resulted in more than 3.5 log10 CFU/g colonization in the poult cecum. The cecal colonization, dissemination to internal organs, and tissue

  3. Analysis of regional banks' efforts to promote energy conservation among commercial customers. Task II

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-30

    The study approach explored the hypothesis that regional banks can play an important role in disseminating energy conservation information to their commercial/industrial customers. The four phases of the study are described in detail. (MCW)

  4. Collaborative Approaches in Developing Environmental and Safety Management Systems for Commercial Space Transportation

    Science.gov (United States)

    Zee, Stacey; Murray, D.

    2009-01-01

    The Federal Aviation Administration (FAA), Office of Commercial Space Transportation (AST) licenses and permits U.S. commercial space launch and reentry activities, and licenses the operation of non-federal launch and reentry sites. ASTs mission is to ensure the protection of the public, property, and the national security and foreign policy interests of the United States during commercial space transportation activities and to encourage, facilitate, and promote U.S. commercial space transportation. AST faces unique challenges of ensuring the protection of public health and safety while facilitating and promoting U.S. commercial space transportation. AST has developed an Environmental Management System (EMS) and a Safety Management System (SMS) to help meet its mission. Although the EMS and SMS were developed independently, the systems share similar elements. Both systems follow a Plan-Do-Act-Check model in identifying potential environmental aspects or public safety hazards, assessing significance in terms of severity and likelihood of occurrence, developing approaches to reduce risk, and verifying that the risk is reduced. This paper will describe the similarities between ASTs EMS and SMS elements and how AST is building a collaborative approach in environmental and safety management to reduce impacts to the environment and risks to the public.

  5. An Approach to Building a Learning Management System that Emphasizes on Incorporating Individualized Dissemination with Intelligent Tutoring

    Science.gov (United States)

    Ghosh, Sreya

    2017-02-01

    This article proposes a new six-model architecture for an intelligent tutoring system to be incorporated in a learning management system with domain-independence feature and individualized dissemination. The present six model architecture aims to simulate a human tutor. Some recent extensions of using intelligent tutoring system (ITS) explores learning management systems to behave as a real teacher during a teaching-learning process, by taking care of, mainly, the dynamic response system. However, the present paper argues that to mimic a human teacher it needs not only the dynamic response but also the incorporation of the teacher's dynamic review of students' performance and keeping track of their current level of understanding. Here, the term individualization has been used to refer to tailor making of contents and its dissemination fitting to the individual needs and capabilities of learners who is taking a course online and is subjected to teaching in absentia. This paper describes how the individual models of the proposed architecture achieves the features of ITS.

  6. Innovative Approaches for the Dissemination of Near Real-time Geostationary Satellite Data for Terrestrial and Space Weather Applications

    Science.gov (United States)

    Jedlovec, G.; McGrath, K.; Meyer, P. J.; Berndt, E.

    2017-12-01

    A GOES-R series receiving station has been installed at the NASA Marshall Space Flight Center (MSFC) to support GOES-16 transition-to-operations projects of NASA's Earth science program and provide a community portal for GOES-16 data access. This receiving station is comprised of a 6.5-meter dish; motor-driven positioners; Quorum feed and demodulator; and three Linux workstations for ingest, processing, display, and subsequent product generation. The Community Satellite Processing Package (CSPP) is used to process GOES Rebroadcast data from the Advanced Baseline Imager (ABI), Geostationary Lightning Mapper (GLM), Solar Ultraviolet Imager (SUVI), Extreme Ultraviolet and X-ray Irradiance Sensors (EXIS), and Space Environment In-Situ Suite (SEISS) into Level 1b and Level 2 files. GeoTIFFs of the imagery from several of these instruments are ingested into an Esri Arc Enterprise Web Map Service (WMS) server with tiled imagery displayable through a web browser interface or by connecting directly to the WMS with a Geographic Information System software package. These data also drive a basic web interface where users can manually zoom to and animate regions of interest or acquire similar results using a published Application Program Interface. While not as interactive as a WMS-driven interface, this system is much more expeditious with generating and distributing requested imagery. The legacy web capability enacted for the predecessor GOES Imager currently supports approximately 500,000 unique visitors each month. Dissemination capabilities have been refined to support a significantly larger number of anticipated users. The receiving station also supports NASA's Short-term Prediction, Research, and Transition Center's (SPoRT) project activities to dissemination near real-time ABI RGB products to National Weather Service National Centers, including the Satellite Analysis Branch, National Hurricane Center, Ocean Prediction Center, and Weather Prediction Center, where they

  7. Dynamic partnership: A new approach to EM technology commercialization and deployment

    International Nuclear Information System (INIS)

    Daly, D.J.; Erickson, T.A.; Groenewold, G.H.

    1996-01-01

    The task of restoring nuclear defense complex sites under the U.S. Department of Energy (DOE) Environmental Management (EM) Program presents an unprecedented challenge to the environmental restoration community. Effective and efficient cleanup requires the timely development or modification of novel cleanup technologies applicable to radioactive wastes. Fostering the commercialization of these innovative technologies is the mission of EM-50, the EM Program Office of Science and Technology. However, efforts are often arrested at the open-quotes valley of death,close quotes the general term for barriers to demonstration, commercialization, and deployment. The Energy ampersand Environmental Research Center (EERC), a not-for-profit, contract-supported organization focused on research, development, demonstration, and commercialization (RDD ampersand C) of energy and environmental technologies, is in the second year of a cooperative agreement with the U.S. Department of Energy (DOE) Morgantown Energy Technology Center (METC) designed to deliver EM technologies into the commercial marketplace through a unique combination of technical support, real-world demonstration, and brokering. This paper profiles this novel approach, termed open-quotes Dynamic Partnership,close quotes and reviews the application of this concept to the ongoing commercialization and deployment of four innovative cleanup technologies. 2 tabs

  8. Food safety objective approach for controlling Clostridium botulinum growth and toxin production in commercially sterile foods.

    Science.gov (United States)

    Anderson, N M; Larkin, J W; Cole, M B; Skinner, G E; Whiting, R C; Gorris, L G M; Rodriguez, A; Buchanan, R; Stewart, C M; Hanlin, J H; Keener, L; Hall, P A

    2011-11-01

    As existing technologies are refined and novel microbial inactivation technologies are developed, there is a growing need for a metric that can be used to judge equivalent levels of hazard control stringency to ensure food safety of commercially sterile foods. A food safety objective (FSO) is an output-oriented metric that designates the maximum level of a hazard (e.g., the pathogenic microorganism or toxin) tolerated in a food at the end of the food supply chain at the moment of consumption without specifying by which measures the hazard level is controlled. Using a risk-based approach, when the total outcome of controlling initial levels (H(0)), reducing levels (ΣR), and preventing an increase in levels (ΣI) is less than or equal to the target FSO, the product is considered safe. A cross-disciplinary international consortium of specialists from industry, academia, and government was organized with the objective of developing a document to illustrate the FSO approach for controlling Clostridium botulinum toxin in commercially sterile foods. This article outlines the general principles of an FSO risk management framework for controlling C. botulinum growth and toxin production in commercially sterile foods. Topics include historical approaches to establishing commercial sterility; a perspective on the establishment of an appropriate target FSO; a discussion of control of initial levels, reduction of levels, and prevention of an increase in levels of the hazard; and deterministic and stochastic examples that illustrate the impact that various control measure combinations have on the safety of well-established commercially sterile products and the ways in which variability all levels of control can heavily influence estimates in the FSO risk management framework. This risk-based framework should encourage development of innovative technologies that result in microbial safety levels equivalent to those achieved with traditional processing methods.

  9. The Opportunity in Commercial Approaches for Future NASA Deep Space Exploration Elements

    Science.gov (United States)

    Zapata, Edgar

    2017-01-01

    In 2011, NASA released a report assessing the market for commercial crew and cargo services to low Earth orbit (LEO). The report stated that NASA had spent a few hundred million dollars in the Commercial Orbital Transportation Services (COTS) program on the portion related to the development of the Falcon 9 launch vehicle. Yet a NASA cost model predicted the cost would have been significantly more with a non-commercial cost-plus contracting approach. By 2016 a NASA request for information stated it must "maximize the efficiency and sustainability of the Exploration Systems development programs", as "critical to free resources for reinvestment...such as other required deep space exploration capabilities." This work joins the previous two events, showing the potential for commercial, public private partnerships, modeled on programs like COTS, to reduce the cost to NASA significantly for "...other required deep space exploration capabilities." These other capabilities include landers, stages and more. We mature the concept of "costed baseball cards", adding cost estimates to NASA's space systems "baseball cards." We show some potential costs, including analysis, the basis of estimates, data sources and caveats to address a critical question - based on initial assessment, are significant agency resources justified for more detailed analysis and due diligence to understand and invest in public private partnerships for human deep space exploration systems? The cost analysis spans commercial to cost-plus contracting approaches, for smaller elements vs. larger, with some variation for lunar or Mars. By extension, we delve briefly into the potentially much broader significance of the individual cost estimates if taken together as a NASA investment portfolio where public private partnership are stitched together for deep space exploration. How might multiple improvements in individual systems add up to NASA human deep space exploration achievements, realistically, affordably

  10. New trends in safety approach for commercial LMFBRS after SPX1

    International Nuclear Information System (INIS)

    Bergeonneau, P.; Moreau, J.; Cowking, C.B.; Friedel, G.; Pezzxilli, M.

    1988-01-01

    The experience gained from SPX1 project safety studies shows the trends for the definition of the new safety approach for the next generation of commercial LMFBR's. New trends in safety criteria, as seen in Europe, are presented in the first part of this paper. It is shown that they greatly emphasize the prevention actions even for minor events which can, in certain cases, lead to severe accidents. In the second part, an attempt is made to compare these new trends in Europe with the ones developed in the USA that put forward the inherent safety approach

  11. Partnership for Healthier Asians: Disseminating Evidence-Based Practices in Asian-American Communities Using a Market-Oriented and Multilevel Approach

    Science.gov (United States)

    Kim, Karen; Quinn, Michael; Chandrasekar, Edwin; Patel, Reena

    2016-01-01

    Background One of the greatest challenges facing health promotion and disease prevention is translating research findings into evidence-based practices (EBP). There is currently a limited research base to inform the design of dissemination action plans, especially within medically underserved communities. Objective The objective of this paper is to describe an innovative study protocol to disseminate colorectal cancer (CRC) screening guidelines in seven Asian subgroups. Methods This study integrated a market-oriented Push-Pull-Infrastructure Model, Diffusion of Innovation Theory, and community-based participatory research approach to create a community-centered dissemination framework. Consumer research, through focus groups and community-wide surveys, was centered on the adopters to ensure a multilevel intervention was well designed and effective. Results Collaboration took place between an academic institution and eight community-based organizations. These groups worked together to conduct thorough consumer research. A sample of 72 Asian Americans participated in 8 focus groups, and differences were noted across ethnic groups. Furthermore, 464 community members participated in an Individual Client Survey. Most participants agreed that early detection of cancer was important (434/464, 93.5%), cancer could happen to anyone (403/464, 86.9%), CRC could be prevented (344/464, 74.1%), and everyone should screen for CRC (389/464, 83.8%). However, 35.8% (166/464) of participants also felt that people were better off not knowing it they had cancer, and 45.5% (211/464) would screen only when they had symptoms. Most participants indicated that they would screen upon their doctor’s recommendation, but half reported that they only saw a doctor when they were sick. Data collection currently is underway for a multilevel intervention (community health advisor and social marketing campaign) and will conclude March 2016. We expect that analysis and results will be available by

  12. Partnership for Healthier Asians: Disseminating Evidence-Based Practices in Asian-American Communities Using a Market-Oriented and Multilevel Approach.

    Science.gov (United States)

    Kim, Karen; Quinn, Michael; Chandrasekar, Edwin; Patel, Reena; Lam, Helen

    2016-06-16

    One of the greatest challenges facing health promotion and disease prevention is translating research findings into evidence-based practices (EBP). There is currently a limited research base to inform the design of dissemination action plans, especially within medically underserved communities. The objective of this paper is to describe an innovative study protocol to disseminate colorectal cancer (CRC) screening guidelines in seven Asian subgroups. This study integrated a market-oriented Push-Pull-Infrastructure Model, Diffusion of Innovation Theory, and community-based participatory research approach to create a community-centered dissemination framework. Consumer research, through focus groups and community-wide surveys, was centered on the adopters to ensure a multilevel intervention was well designed and effective. Collaboration took place between an academic institution and eight community-based organizations. These groups worked together to conduct thorough consumer research. A sample of 72 Asian Americans participated in 8 focus groups, and differences were noted across ethnic groups. Furthermore, 464 community members participated in an Individual Client Survey. Most participants agreed that early detection of cancer was important (434/464, 93.5%), cancer could happen to anyone (403/464, 86.9%), CRC could be prevented (344/464, 74.1%), and everyone should screen for CRC (389/464, 83.8%). However, 35.8% (166/464) of participants also felt that people were better off not knowing it they had cancer, and 45.5% (211/464) would screen only when they had symptoms. Most participants indicated that they would screen upon their doctor's recommendation, but half reported that they only saw a doctor when they were sick. Data collection currently is underway for a multilevel intervention (community health advisor and social marketing campaign) and will conclude March 2016. We expect that analysis and results will be available by June 2016. This study outlines a

  13. Dynamic partnership: A new approach to EM technology commercialization and deployment

    International Nuclear Information System (INIS)

    Daly, D.J.; Erickson, T.A.; Groenewold, G.H.

    1996-01-01

    The cleanup of nuclear defense complex sites under the U.S. Department of Energy (DOE) Environmental Management (EM) Program presents an unprecedented challenge to the environmental sector. Effective and efficient cleanup of EM sites requires the timely development or modification of cleanup technologies. Facilitating the development of technologies to meet DOE goals for site cleanup is the responsibility of EM-50, the EM Program Office of Science and Technology. However, efforts are often arrested at the open-quotes valley of death,close quotes the general term for barriers to demonstration, commercialization, and deployment. The Energy ampersand Environmental Research Center (EERC), a not-for-profit, contract-supported organization focused on research, development, demonstration, and commercialization (RDD ampersand C) of energy and environmental technologies, is in the second year of a Cooperative Agreement with DOE's Morgantown Energy Technology Center (METC) designed to deliver EM technologies into the commercial marketplace through a unique combination of technical support, real-world demonstration, and brokering. This paper profiles this novel approach, termed open-quotes Dynamic Partnership,close quotes and reviews the application of this concept to the ongoing commercialization and deployment of four innovative cleanup technologies

  14. An energy systems engineering approach to the optimal design of energy systems in commercial buildings

    International Nuclear Information System (INIS)

    Liu Pei; Pistikopoulos, Efstratios N.; Li Zheng

    2010-01-01

    Energy consumption in commercial buildings accounts for a significant proportion of worldwide energy consumption. Any increase in the energy efficiency of the energy systems for commercial buildings would lead to significant energy savings and emissions reductions. In this work, we introduce an energy systems engineering framework towards the optimal design of such energy systems with improved energy efficiency and environmental performance. The framework features a superstructure representation of the various energy technology alternatives, a mixed-integer optimization formulation of the energy systems design problem, and a multi-objective design optimization solution strategy, where economic and environmental criteria are simultaneously considered and properly traded off. A case study of a supermarket energy systems design is presented to illustrate the key steps and potential of the proposed energy systems engineering approach.

  15. Analysis of the Possibility of Disseminating the “Game-Movement-Development” Approach in Early Childhood Education

    Directory of Open Access Journals (Sweden)

    Jera Gregorc

    2015-09-01

    Full Text Available Introduction. The “game-movement-development” (GMD approach was conceived in the light of contemporary scientific knowledge in the field of kinesiology, neuro-education, pedagogy, and psychology related to the pre-school period. The approach has been implemented for over 15 years in a selected kindergarten. The aim of the study was to examine the feasibility of applying the new GMD approach in different kindergartens depending on the children’s age and according to selected quality indicators.

  16. A feasible approach to implement a commercial scale CANDU fuel manufacturing plant in Egypt

    International Nuclear Information System (INIS)

    El-Shehawy, I.; El-Sharaky, M.; Yasso, K.; Selim, I.; Graham, N.; Newington, D.

    1995-01-01

    Many planning scenarios have been examined to assess and evaluate the economic estimates for implementing a commercial scale CANDU fuel manufacturing plant in Egypt. The cost estimates indicated strong influence of the annual capital costs on total fuel manufacturing cost; this is particularly evident in a small initial plant where the proposed design output is only sufficient to supply reload fuel for a single CANDU-6 reactor. A modular approach is investigated as a possible way, to reduce the capital costs for a small initial fuel plant. In this approach the plant would do fuel assembly operations only and the remainder of a plant would be constructed and equipped in the stages when high production volumes can justify the capital expenses. Such approach seems economically feasible for implementing a small scale CANDU fuel manufacturing plant in developing countries such as Egypt and further improvement could be achieved over the years of operation. (author)

  17. MOOC design – Dissemination to the masses or facilitation of social learning and a deep approach to learning?

    Directory of Open Access Journals (Sweden)

    Inger-Marie Falgren Christensen

    2016-11-01

    Full Text Available This article accounts for the design of the massive open online course (MOOC Hans Christian Andersen’s Fairy tales on FutureLearn and reports on the effectiveness of this design in terms of engaging learners in social learning and encouraging a deep approach to learning. A learning pathway was designed that provided learners with relevant knowledge, allowed them to practice their analysis skills and provided model responses. In the first run of the MOOC, a light facilitation approach was used to motivate and engage learners. In the second run, this was supplemented with live Q & A sessions and increased educator feedback. Course data show that that some learners use the space provided for social interaction and mutual support. A learning pathway that engages learners in discussion and progression from week to week facilitates a deep approach to learning. However, this requires more support from the educators and the course host.

  18. MOOC Design – Dissemination to the Masses or Facilitation of Social Learning and a Deep Approach to Learning?

    DEFF Research Database (Denmark)

    Christensen, Inger-Marie F.; Dam Laursen, Mette; Bøggild, Jacob

    2016-01-01

    This article accounts for the design of the massive open online course (MOOC) Hans Christian Andersen’s Fairy tales on FutureLearn and reports on the effectiveness of this design in terms of engaging learners in social learning and encouraging a deep approach to learning. A learning pathway...... and increased educator feedback. Course data show that that some learners use the space provided for social interaction and mutual support. A learning pathway that engages learners in discussion and progression from week to week facilitates a deep approach to learning. However, this requires more support from...

  19. The lab-on-PCB approach: tackling the μTAS commercial upscaling bottleneck.

    Science.gov (United States)

    Moschou, Despina; Tserepi, Angeliki

    2017-04-11

    Commercialization of lab-on-a-chip devices is currently the "holy grail" within the μTAS research community. While a wide variety of highly sophisticated chips which could potentially revolutionize healthcare, biology, chemistry and all related disciplines are increasingly being demonstrated, very few chips are or can be adopted by the market and reach the end-users. The major inhibition factor lies in the lack of an established commercial manufacturing technology. The lab-on-printed circuit board (lab-on-PCB) approach, while suggested many years ago, only recently has re-emerged as a very strong candidate, owing to its inherent upscaling potential: the PCB industry is well established all around the world, with standardized fabrication facilities and processes, but commercially exploited currently only for electronics. Owing to these characteristics, complex μTASs integrating microfluidics, sensors, and electronics on the same PCB platform can easily be upscaled, provided more processes and prototypes adapted to the PCB industry are proposed. In this article, we will be reviewing for the first time the PCB-based prototypes presented in the literature to date, highlighting the upscaling potential of this technology. The authors believe that further evolution of this technology has the potential to become a much sought-after standardized industrial fabrication technology for low-cost μTASs, which could in turn trigger the projected exponential market growth of μTASs, in a fashion analogous to the revolution of Si microchips via the CMOS industry establishment.

  20. Systems engineering approach to U.S. Department of Energy's commercial nuclear waste transportation program

    International Nuclear Information System (INIS)

    Pardue, W.M.

    1987-01-01

    The U.S Department of Energy (DOE) has been given the responsibility of developing a program to transport commercially produced spent nuclear fuel and high-level radioactive wastes to disposal sites or storage facilities safely and cost-effectively. To accomplish this task it is desirable to plan, perform, and document all technical activities based on systems engineering principles. This paper presents an overview of the systems engineering approach being developed by Battelle for consideration by DOE, specifically the early identification of the required technical activities and approaches to technical management and decision making. The program should support the development of an integrated, well-documented transportation system acceptable to regulatory agencies and the public

  1. Gathering the Voices: Disseminating the Message of the Holocaust for the Digital Generation by Applying an Interdisciplinary Approach

    Directory of Open Access Journals (Sweden)

    Angela Shapiro

    2014-08-01

    Full Text Available The aim of the Gathering the Voices project is to gather testimonies from Holocaust survivors who have made their home in Scotland and to make these testimonies available on the World Wide Web. The project commenced in 2012, and a key outcome of the project is to educate current and future generations about the resilience of these survivors. Volunteers from the Jewish community are collaborating with staff and undergraduate students in Glasgow Caledonian University in developing innovative approaches to engage with school children. These multimedia approaches are essential, as future generations will be unable to interact in person with Holocaust survivors. By students being active participants in the project, they will learn more about the Holocaust and recognize the relevance of these testimonies in today’s society. Although some of the survivors have been interviewed about their journeys in fleeing from the Nazi atrocities, for all of the interviewees, this is the first time that they have been asked about their lives once they arrived in the United Kingdom. The interviews have also focused on citizenship and integration into society. The project is not yet completed, and an evaluation will be taking place to measure the effectiveness of the project in communicating its message to the public.

  2. A fast track approach to commercializing the sodium cooled fast reactor

    International Nuclear Information System (INIS)

    Boardman, C.E.; Hui, Marvin; Carroll, Douglas

    1999-01-01

    As a result of more than 50 years of Liquid Metal Reactor design and development work the basic technology is well understood. However, commercialization of the Fast Breeder Reactor (FBR) has been delayed while various approaches to achieving competitive plant and fuel cycle costs are explored, developed, and demonstrated in prototype systems. Most designers have elected to take advantage of the economy of scale but are burdened by the cost and risk associated with the need for incremental scale up through the design, construction, and operation of multiple demonstration plants. An alternative commercialization path developed by GE would utilize a modular plant design to reduce the plant construction, R and D, and economic risk associated with the need to build multiple demonstration plants to reach a competitive size'. The key question is can a modular FBR compete with alternative electrical generation systems? Recently completed studies indicate that the answer to this question is yes if the modular plant designers keep the design simple by incorporating passive safety features and optimizing the manner in which supporting service systems are shared. (author)

  3. A Machine Learning Approach for Business Intelligence Analysis using Commercial Shipping Transaction Data

    Energy Technology Data Exchange (ETDEWEB)

    Bramer, Lisa M.; Chatterjee, Samrat; Holmes, Aimee E.; Robinson, Sean M.; Bradley, Steven F.; Webb-Robertson, Bobbie-Jo M.

    2015-09-30

    Business intelligence problems are particularly challenging due to the use of large volume and high velocity data in attempts to model and explain complex underlying phenomena. Incremental machine learning based approaches for summarizing trends and identifying anomalous behavior are often desirable in such conditions to assist domain experts in characterizing their data. The overall goal of this research is to develop a machine learning algorithm that enables predictive analysis on streaming data, detects changes and anomalies in the data, and can evolve based on the dynamic behavior of the data. Commercial shipping transaction data for the U.S. is used to develop and test a Naïve Bayes model that classifies several companies into lines of businesses and demonstrates an ability to predict when the behavior of these companies changes by venturing into other lines of businesses.

  4. Multidisciplinary approach to evaluating welfare of veal calves in commercial facilities.

    Science.gov (United States)

    Stull, C L; McDonough, S P

    1994-09-01

    Due to pending legislation and public concerns, a multidisciplinary approach was designed to investigate the welfare of special-fed veal calves in commercial veal facilities. Concerns included housing conditions, dietary regimens, management practices, and behavioral aspects imposed on special-fed calves. Four categories of parameters including environment and housing, nutrition, health and stress, and behavior provided a broad base of evaluating veal systems. Observations and samples were collected on 550 Holstein bull calves located in 10 commercial veal facilities. Each facility was visited to collect data during wk 0 (week of arrival of the calves), 2, 4, 8, 12, and 16. Nine facilities used individual stalls 48 to 55 cm in width with tethers attached to the front of the stalls. One facility housed 30 calves in group pens after obtaining calves at 8 wk of age. Ammonia, carbon monoxide, and hydrogen sulfide gas did not exceed the permissible limit for humans in any facility. All facilities exceeded the 2-foot-candle recommendation for lighting. The average daily gain of calves was .85 kg during wk 0 to 8 and 1.18 kg during wk 8 to 16. Dietary iron levels decreased from 209 ppm at wk 0 to 32 ppm at wk 16. At 16 wk, 25% of calves were marginally anemic and 10% clinically anemic. Overall mortality was 4.2%. Stress indices such as plasma cortisol concentrations or neutrophil to lymphocyte ratios declined as calves approached market weight. In either pens or stalls, calves spent approximately 25 and 75% of time in standing and lying positions, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

  5. Modern approaches to the assessment of the cost of commercial bank

    Directory of Open Access Journals (Sweden)

    Natal’ya I. Malykh

    2016-01-01

    Full Text Available Financial analysis and assessment of the company’s activity in the market economy plays an important role as an indicator of the organization reliability and its competitiveness. For a commercial bank, a positive opinion on its financial position becomes even more important as not only the effectiveness of the bank’s operation, but also its clients interest depend on the degree of the bank’s reliability.A comprehensive activity assessment of a commercial bank in addition to financial analysis is the analysis of risks, strengths and weaknesses of the bank and the business valuation of a commercial bank. Business valuation – topical areas of financial management, and eventually its importance will only increase.Financial institution should be regarded not only from the view of financial statements as an entity, but also from the view of the investment attractiveness as a business unit for a comprehensive idea of its activity.The economic activity of the banking sector is considered by the authors as an operating business unit – bank. The article considers the modern approaches to the valuation of a commercial bank, the necessity of taking into account the specifics of banking activities in the evaluation, the difficulties of assessment, typical for the financial services’ sector.The authors note that the business valuation of a commercial bank shall apply a single method: estimate the cost of equity capital (and not the company, as it is customary in order to apply standard accounting rules, and use only cash flows that could be traced – dividends.For the purposes of evaluating the absolute value of the bank it can be applied the model of discounted dividends, provided that only equity will play the role of capital, and cash flows, except for the dividend, can be omitted (due to the complexity of the calculation.In comparison with non-financial enterprises, some of multipliers for comparative approach to evaluation cannot be

  6. A systems approach to the commercialization of space communications technology - The NASA/JPL Mobile Satellite Program

    Science.gov (United States)

    Weber, William J., III; Gray, Valerie W.; Jackson, Byron; Steele, Laura C.

    1991-10-01

    This paper discusss the systems approach taken by NASA and the Jet Propulsion Laboratory in the commercialization of land-mobile satellite services (LMSS) in the United States. As the lead center for NASA's Mobile Satellite Program, JPL was involved in identifying and addressing many of the key barriers to commercialization of mobile satellite communications, including technical, economic, regulatory and institutional risks, or uncertainties. The systems engineering approach described here was used to mitigate these risks. The result was the development and implementation of the JPL Mobile Satellite Experiment Project. This Project included not only technology development, but also studies to support NASA in the definition of the regulatory, market, and investment environments within which LMSS would evolve and eventually operate, as well as initiatives to mitigate their associated commercialization risks. The end result of these government-led endeavors was the acceleration of the introduction of commercial mobile satellite services, both nationally and internationally.

  7. Dissemination Strategy Report

    DEFF Research Database (Denmark)

    Badger, Merete; Kjems, Jørgen; Farinetti, Laura

    This report describes the dissemination and exploitation strategy for project Virtual Campus Hub (EU FP7 contract RI-283746). The project duration is October 2011-13 and the dissemination and exploitation plan will be revised continuously during the project’s lifecycle.......This report describes the dissemination and exploitation strategy for project Virtual Campus Hub (EU FP7 contract RI-283746). The project duration is October 2011-13 and the dissemination and exploitation plan will be revised continuously during the project’s lifecycle....

  8. Solvency II approach to the risk management in commercial insurance companies

    Directory of Open Access Journals (Sweden)

    Eva Vávrová

    2010-01-01

    Full Text Available In the year 2001, the European Comission started to revise the legislation Solvency I and to implement a new approach called Solvency II. The regulation called Solvency II is based on regulation considering management of risks of commercial insurance companies. Changes on financial markets and the contemporary financial crisis made financial authorities to formulate principles of regulation based on risk management. Commercial insurance companies across Europe will face a considerable amount of work to be ready for requirements related with Solvency II implementation in the year 2012. Rating agencies, regulators and investors today are demanding that insurers provide detailed assessments of their risk tolerance and quantify the adequacy of their economic capital. To complete such assessments requires a credible baseline for underwriting volatility. Modern portfolio theory for assets teaches that increasing the number of stocks in a portfolio will diversify and reduce the portfolio risk, but will not eliminate risk completely, the systemic market risk remains. In the same way, insurers can reduce underwriting volatility by increasing account volume, but they cannot reduce their volatility to zero. A certain level of systemic insurance risk will always remain, due to factors such as for example the underwriting cycle, macroeconomic factors, legal changes and weather.This presented scientific paper focuses on an analysis of specific goals of the regulation Solvency II and the structure of second pillar of the three-pillar construction (similarity with Basel II banking regulation of Solvency II. The paper was written as part of research project MSM 6215648904, carried out by the Faculty of Business and Economics, under the title “The Czech Republic in the pro­ces­ses of integration and globalization, and the development of the agriculture and service sector in the new conditions of the integrated European market”, following the goals and

  9. A consortium approach to commercialized Westinghouse solid oxide fuel cell technology

    Science.gov (United States)

    Casanova, Allan

    baseload applications are a new segment, and because deregulation will continue to shake up the mature traditional power generation market, the commercial risks of launching a new product at this time are unique and considerable. Hence, a collaborative approach to commercialization is deemed desirable and appropriate, and collaboration with GT manufacturers and utilities will be addressed in this paper.

  10. Schmallenberg Virus Circulation in Culicoides in Belgium in 2012: Field Validation of a Real Time RT-PCR Approach to Assess Virus Replication and Dissemination in Midges

    Science.gov (United States)

    De Regge, Nick; Madder, Maxime; Deblauwe, Isra; Losson, Bertrand; Fassotte, Christiane; Demeulemeester, Julie; Smeets, François; Tomme, Marie; Cay, Ann Brigitte

    2014-01-01

    Indigenous Culicoides biting midges are suggested to be putative vectors for the recently emerged Schmallenberg virus (SBV) based on SBV RNA detection in field-caught midges. Furthermore, SBV replication and dissemination has been evidenced in C. sonorensis under laboratory conditions. After SBV had been detected in Culicoides biting midges from Belgium in August 2011, it spread all over the country by the end of 2011, as evidenced by very high between-herd seroprevalence rates in sheep and cattle. This study investigated if a renewed SBV circulation in midges occurred in 2012 in the context of high seroprevalence in the animal host population and evaluated if a recently proposed realtime RT-PCR approach that is meant to allow assessing the vector competence of Culicoides for SBV and bluetongue virus under laboratory conditions was applicable to field-caught midges. Therefore midges caught with 12 OVI traps in four different regions in Belgium between May and November 2012, were morphologically identified, age graded, pooled and tested for the presence of SBV RNA by realtime RT-PCR. The results demonstrate that although no SBV could be detected in nulliparous midges caught in May 2012, a renewed but short lived circulation of SBV in parous midges belonging to the subgenus Avaritia occured in August 2012 at all four regions. The infection prevalence reached up to 2.86% in the south of Belgium, the region where a lower seroprevalence was found at the end of 2011 than in the rest of the country. Furthermore, a frequency analysis of the Ct values obtained for 31 SBV-S segment positive pools of Avaritia midges showed a clear bimodal distribution with peaks of Ct values between 21–24 and 33–36. This closely resembles the laboratory results obtained for SBV infection of C. sonorensis and implicates indigenous midges belonging to the subgenus Avaritia as competent vectors for SBV. PMID:24466312

  11. Assessing commercial livestock appropriation of the productive capacity of US drylands: A remote sensing approach

    Science.gov (United States)

    Washington-Allen, R. A.; Mitchell, J. E.; Oslen, H. E.

    2008-12-01

    The "State of Nation's Ecosystems" by the Heinz Institute and the recent "Millennium Ecosystem Assessment of Drylands" concluded that the amount of desertification and the extent to which human management actions contribute to this process is unknown at national to global spatial scales. This is primarily due to lack of studies at these large spatial scales and the temporal scales (> a 15-year time series of data) necessary to separate the effects of anthropogenic practices from climate change on Drylands. Consequently, this research seeks to develop procedures for determining 1) the area of Drylands within the United States where commercial grazing livestock occur or the livestock ecological footprint and 2) the impact of the footprint on the US's productive capacity. Our approach has been to develop a pilot geodatabase of year 2002 data that includes administrative boundaries, the Moderate Resolution Infrared Spectroradiometer's (MODIS) measures of gross and net primary productivity (GPP and NPP, respectively), US Department of Agriculture's National Agricultural Statistics Service's (USDA-NASS) county-level data on cattle, sheep, and goat inventories, transportation and power consumption networks, dryland extent, and land cover/land use. Secondly, the ratio of 1-km2 gridded mean annual potential evapotranspiration (MAPET) to mean annual precipitation (MAP) data were used to define the 50-year mean dryland extent in accordance with the United Nations Convention to Combat Desertification's definition of Drylands, the aridity index (AI) ≤ 0.65. Urban features, including transportation, power consumption, and land use/land cover, were subtracted from this dryland map to further refine it. The NASS tabular data was then related to the counties boundary map thus producing a county-level livestock number map that was then intersected with the dryland extent map to yield the US livestock ecological footprint. Lastly, this footprint map was then converted to a

  12. An Efficient Approach for Mars Sample Return Using Emerging Commercial Capabilities.

    Science.gov (United States)

    Gonzales, Andrew A; Stoker, Carol R

    2016-06-01

    Mars Sample Return is the highest priority science mission for the next decade as recommended by the 2011 Decadal Survey of Planetary Science [1]. This article presents the results of a feasibility study for a Mars Sample Return mission that efficiently uses emerging commercial capabilities expected to be available in the near future. The motivation of our study was the recognition that emerging commercial capabilities might be used to perform Mars Sample Return with an Earth-direct architecture, and that this may offer a desirable simpler and lower cost approach. The objective of the study was to determine whether these capabilities can be used to optimize the number of mission systems and launches required to return the samples, with the goal of achieving the desired simplicity. All of the major element required for the Mars Sample Return mission are described. Mission system elements were analyzed with either direct techniques or by using parametric mass estimating relationships. The analysis shows the feasibility of a complete and closed Mars Sample Return mission design based on the following scenario: A SpaceX Falcon Heavy launch vehicle places a modified version of a SpaceX Dragon capsule, referred to as "Red Dragon", onto a Trans Mars Injection trajectory. The capsule carries all the hardware needed to return to Earth Orbit samples collected by a prior mission, such as the planned NASA Mars 2020 sample collection rover. The payload includes a fully fueled Mars Ascent Vehicle; a fueled Earth Return Vehicle, support equipment, and a mechanism to transfer samples from the sample cache system onboard the rover to the Earth Return Vehicle. The Red Dragon descends to land on the surface of Mars using Supersonic Retropropulsion. After collected samples are transferred to the Earth Return Vehicle, the single-stage Mars Ascent Vehicle launches the Earth Return Vehicle from the surface of Mars to a Mars phasing orbit. After a brief phasing period, the Earth Return

  13. An Efficient Approach for Mars Sample Return Using Emerging Commercial Capabilities

    Science.gov (United States)

    Gonzales, Andrew A.; Stoker, Carol R.

    2016-01-01

    Mars Sample Return is the highest priority science mission for the next decade as recommended by the 2011 Decadal Survey of Planetary Science [1]. This article presents the results of a feasibility study for a Mars Sample Return mission that efficiently uses emerging commercial capabilities expected to be available in the near future. The motivation of our study was the recognition that emerging commercial capabilities might be used to perform Mars Sample Return with an Earth-direct architecture, and that this may offer a desirable simpler and lower cost approach. The objective of the study was to determine whether these capabilities can be used to optimize the number of mission systems and launches required to return the samples, with the goal of achieving the desired simplicity. All of the major element required for the Mars Sample Return mission are described. Mission system elements were analyzed with either direct techniques or by using parametric mass estimating relationships. The analysis shows the feasibility of a complete and closed Mars Sample Return mission design based on the following scenario: A SpaceX Falcon Heavy launch vehicle places a modified version of a SpaceX Dragon capsule, referred to as “Red Dragon”, onto a Trans Mars Injection trajectory. The capsule carries all the hardware needed to return to Earth Orbit samples collected by a prior mission, such as the planned NASA Mars 2020 sample collection rover. The payload includes a fully fueled Mars Ascent Vehicle; a fueled Earth Return Vehicle, support equipment, and a mechanism to transfer samples from the sample cache system onboard the rover to the Earth Return Vehicle. The Red Dragon descends to land on the surface of Mars using Supersonic Retropropulsion. After collected samples are transferred to the Earth Return Vehicle, the single-stage Mars Ascent Vehicle launches the Earth Return Vehicle from the surface of Mars to a Mars phasing orbit. After a brief phasing period, the Earth

  14. An efficient approach for Mars Sample Return using emerging commercial capabilities

    Science.gov (United States)

    Gonzales, Andrew A.; Stoker, Carol R.

    2016-06-01

    Mars Sample Return is the highest priority science mission for the next decade as recommended by the 2011 Decadal Survey of Planetary Science (Squyres, 2011 [1]). This article presents the results of a feasibility study for a Mars Sample Return mission that efficiently uses emerging commercial capabilities expected to be available in the near future. The motivation of our study was the recognition that emerging commercial capabilities might be used to perform Mars Sample Return with an Earth-direct architecture, and that this may offer a desirable simpler and lower cost approach. The objective of the study was to determine whether these capabilities can be used to optimize the number of mission systems and launches required to return the samples, with the goal of achieving the desired simplicity. All of the major element required for the Mars Sample Return mission are described. Mission system elements were analyzed with either direct techniques or by using parametric mass estimating relationships. The analysis shows the feasibility of a complete and closed Mars Sample Return mission design based on the following scenario: A SpaceX Falcon Heavy launch vehicle places a modified version of a SpaceX Dragon capsule, referred to as ;Red Dragon;, onto a Trans Mars Injection trajectory. The capsule carries all the hardware needed to return to Earth Orbit samples collected by a prior mission, such as the planned NASA Mars 2020 sample collection rover. The payload includes a fully fueled Mars Ascent Vehicle; a fueled Earth Return Vehicle, support equipment, and a mechanism to transfer samples from the sample cache system onboard the rover to the Earth Return Vehicle. The Red Dragon descends to land on the surface of Mars using Supersonic Retropropulsion. After collected samples are transferred to the Earth Return Vehicle, the single-stage Mars Ascent Vehicle launches the Earth Return Vehicle from the surface of Mars to a Mars phasing orbit. After a brief phasing period, the

  15. A Law and Economics Approach to Norms in Transnational Commercial Transactions: Incorporation and Internalisation

    NARCIS (Netherlands)

    B. Yuan (Bo)

    2016-01-01

    textabstractIn today’s global economy, a noticeable trend is that the traditional state-law-centred legal framework is increasingly challenged by self-regulatory private orders. Commercial norms, commercial arbitration and social sanctions at the international level have become important

  16. An unbroken chain: approaches to implementing Linked Open Data in libraries: comparing local, open-source, collaborative and commercial systems

    NARCIS (Netherlands)

    Greenall, R.; Koster, L.

    2014-01-01

    This paper compares methods for libraries to interact with the Web of data by assessing the benefits and risks associated with local development, free-and-open-source software, collaborative and commercial solutions. Through a number of case studies, we provide insight into how each approach can be

  17. Dissemination and Exploitation Strategy

    DEFF Research Database (Denmark)

    Badger, Merete; Monaco, Lucio; Fransson, Torsten

    of Technology in Sweden, Politecnico di Torino in Italy, and Eindhoven University of Technology in the Netherlands. The project is partially funded by the European Commission under the 7th Framework Programme (project no. RI-283746). This report describes the final dissemination and exploitation strategy...... for project Virtual Campus Hub. A preliminary dissemination and exploitation plan was setup early in the project as described in the deliverable D6.1 Dissemination strategy paper - preliminary version. The plan has been revised on a monthly basis during the project’s lifecycle in connection with the virtual...

  18. Commercial Aquaponics Approaching the European Market: To Consumers’ Perceptions of Aquaponics Products in Europe

    Directory of Open Access Journals (Sweden)

    Vesna Miličić

    2017-01-01

    Full Text Available The first commercial aquaponics companies are starting up in Europe. The main focus has been on solving technology issues and optimizing production. However, increasing attention is now being paid to certification and regulations linked to aquaponics, as well as the marketing of products and services. The paper presents the results of a study whose main aim was to estimate consumers’ knowledge about aquaponics and their acceptance of aquaponics products in different European regions. An on-line questionnaire was administered to the general public through the aquaponics network of Food and Agriculture COST (European Cooperation in Science and Technology Action FA1305 “The EU Aquaponics Hub—Realising Sustainable Integrated Fish and Vegetable Production for the EU” in 16 European countries. The methodology includes univariate and multivariate statistical techniques. The results show that, on average, attitudes towards aquaponics were positive, showing no significant differences between those who already knew about aquaponics and those who only heard about it through the survey. More than 50% of respondents had never heard of aquaponics, whilst more than 70% had already heard of hydroponics. No more than 17% of respondents were willing to pay more for aquaponically produced products and no more than 40% more when compared to the price of products from conventional farming. The results confirm three different clusters of potential consumers of aquaponics products. They also suggest an urgent need for implementing integrated and holistic approaches involving all stakeholders in aquaponics, in order to define a marketing plan and efficient communication strategies. This COST action, other projects and public decision makers must invest in educating consumers about aquaponics through the organization of guided tours, thematic workshops and tastings of aquaponics products in order to raise their awareness about this new technology. It is

  19. Commercial demand for energy: a disaggregated approach. [Model validation for 1970-1975; forecasting to 2000

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, J.R.; Cohn, S.; Cope, J.; Johnson, W.S.

    1978-04-01

    This report describes the structure and forecasting accuracy of a disaggregated model of commercial energy use recently developed at Oak Ridge National Laboratory. The model forecasts annual commercial energy use by ten building types, five end uses, and four fuel types. Both economic (utilization rate, fuel choice, capital-energy substitution) and technological factors (equipment efficiency, thermal characteristics of buildings) are explicitly represented in the model. Model parameters are derived from engineering and econometric analysis. The model is then validated by simulating commercial energy use over the 1970--1975 time period. The model performs well both with respect to size of forecast error and ability to predict turning points. The model is then used to evaluate the energy-use implications of national commercial buildings standards based on the ASHRAE 90-75 recommendations. 10 figs., 12 tables, 14 refs.

  20. Fat, oil and grease reduction in commercial kitchen ductwork: a novel biological approach

    OpenAIRE

    Mudie, S.; Vahdati, Maria

    2017-01-01

    Recent research has characterised emissions upon cooking a variety of foods in a commercial catering environment in terms of volume, particle size and composition. However, there has been limited focus on the deposition of solid grease in commercial kitchen ductwork, the sustainability of these systems and their implications on the heat recovery potential of kitchen ventilation extract air.\\ud \\ud This paper reviews the literature concerning grease, commonly referred to as Fat, Oils and Greas...

  1. The GETE approach to facilitating the commercialization and use of DOE-developed environmental technologies

    International Nuclear Information System (INIS)

    Harvey, T.N.

    1995-01-01

    The Global Environmental Technology Enterprise (GETE) was conceived to develop and implement strategies to facilitate the commercialization of innovative, cost-effective Department of Energy (DOE)-developed environmental technologies. These strategies are needed to aid DOE's clean-up mission; to break down barriers to commercialization; and to build partnerships between the federal government and private industry in order to facilitate the development and use of innovative environmental technologies

  2. Accounting Education Approach in the Context of New Turkish Commercial Code and Turkish Accounting Standards

    Directory of Open Access Journals (Sweden)

    Cevdet Kızıl

    2014-08-01

    Full Text Available The aim of this article is to investigate the impact of new Turkish commercial code and Turkish accounting standards on accounting education. This study takes advantage of the survey method for gathering information and running the research analysis. For this purpose, questionnaire forms are distributed to university students personally and via the internet.This paper includes significant research questions such as “Are accounting academicians informed and knowledgeable on new Turkish commercial code and Turkish accounting standards?”, “Do accounting academicians integrate new Turkish commercial code and Turkish accounting standards to their lectures?”, “How does modern accounting education methodology and technology coincides with the teaching of new Turkish commercial code and Turkish accounting standards?”, “Do universities offer mandatory and elective courses which cover the new Turkish commercial code and Turkish accounting standards?” and “If such courses are offered, what are their names, percentage in the curriculum and degree of coverage?”Research contributes to the literature in several ways. Firstly, new Turkish commercial code and Turkish accounting standards are current significant topics for the accounting profession. Furthermore, the accounting education provides a basis for the implementations in public and private sector. Besides, one of the intentions of new Turkish commercial code and Turkish accounting standards is to foster transparency. That is definitely a critical concept also in terms of mergers, acquisitions and investments. Stakeholders of today’s business world such as investors, shareholders, entrepreneurs, auditors and government are in need of more standardized global accounting principles Thus, revision and redesigning of accounting educations plays an important role. Emphasized points also clearly prove the necessity and functionality of this research.

  3. Credit risk assessment model for Jordanian commercial banks: Neural scoring approach

    Directory of Open Access Journals (Sweden)

    Hussain Ali Bekhet

    2014-01-01

    Full Text Available Despite the increase in the number of non-performing loans and competition in the banking market, most of the Jordanian commercial banks are reluctant to use data mining tools to support credit decisions. Artificial neural networks represent a new family of statistical techniques and promising data mining tools that have been used successfully in classification problems in many domains. This paper proposes two credit scoring models using data mining techniques to support loan decisions for the Jordanian commercial banks. Loan application evaluation would improve credit decision effectiveness and control loan office tasks, as well as save analysis time and cost. Both accepted and rejected loan applications, from different Jordanian commercial banks, were used to build the credit scoring models. The results indicate that the logistic regression model performed slightly better than the radial basis function model in terms of the overall accuracy rate. However, the radial basis function was superior in identifying those customers who may default.

  4. Helix Nebula and CERN: A Symbiotic approach to exploiting commercial clouds

    CERN Document Server

    Barreiro Megino, Fernando Harald; Kucharczyk, Katarzyna; Medrano Llamas, Ramón; van der Ster, Daniel

    2014-01-01

    The recent paradigm shift toward cloud computing in IT, and general interest in "Big Data" in particular, have demonstrated that the computing requirements of HEP are no longer globally unique. Indeed, the CERN IT department and LHC experiments have already made significant R&D investments in delivering and exploiting cloud computing resources. While a number of technical evaluations of interesting commercial offerings from global IT enterprises have been performed by various physics labs, further technical, security, sociological, and legal issues need to be address before their large-scale adoption by the research community can be envisaged. Helix Nebula - the Science Cloud is an initiative that explores these questions by joining the forces of three European research institutes (CERN, ESA and EMBL) with leading European commercial IT enterprises. The goals of Helix Nebula are to establish a cloud platform federating multiple commercial cloud providers, along with new business models, which can sustain ...

  5. Helix Nebula and CERN: A Symbiotic approach to exploiting commercial clouds

    CERN Multimedia

    Barreiro Megino, Fernando Harald; Kucharczyk, Katarzyna; Medrano Llamas, Ramón; van der Ster, Daniel

    2013-01-01

    The recent paradigm shift toward cloud computing in IT, and general interest in "Big Data" in particular, have demonstrated that the computing requirements of HEP are no longer globally unique. Indeed, the CERN IT department and LHC experiments have already made significant R&D; investments in delivering and exploiting cloud computing resources. While a number of technical evaluations of interesting commercial offerings from global IT enterprises have been performed by various physics labs, further technical, security, sociological, and legal issues need to be address before their large-scale adoption by the research community can be envisaged. Helix Nebula - the Science Cloud is an initiative that explores these questions by joining the forces of three European research institutes (CERN, ESA and EMBL) with leading European commercial IT enterprises. The goals of Helix Nebula are to establish a cloud platform federating multiple commercial cloud providers, along with new business models, which can sustain...

  6. A Simplified Chromatographic Approach to Purify Commercially Available Bovine Submaxillary Mucins (BSM)

    DEFF Research Database (Denmark)

    Madsen, Jan Busk; Pakkanen, Kirsi I.; Duelund, Lars

    2015-01-01

    content and homogeneously distributed size, and in a high yield of 43% from BSM as received from the manufacturer. The purity and composition of commercially acquired BSM were assessed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and mass spectrometry, which verified that BSA...

  7. Further exploration of dissemination bias in qualitative research required to facilitate assessment within qualitative evidence syntheses.

    Science.gov (United States)

    Toews, Ingrid; Booth, Andrew; Berg, Rigmor C; Lewin, Simon; Glenton, Claire; Munthe-Kaas, Heather M; Noyes, Jane; Schroter, Sara; Meerpohl, Joerg J

    2017-08-01

    To conceptualise and discuss dissemination bias in qualitative research. It is likely that the mechanisms leading to dissemination bias in quantitative research, including time lag, language, gray literature, and truncation bias also contribute to dissemination bias in qualitative research. These conceptual considerations have informed the development of a research agenda. Further exploration of dissemination bias in qualitative research is needed, including the extent of non-dissemination and related dissemination bias, and how to assess dissemination bias within qualitative evidence syntheses. We also need to consider the mechanisms through which dissemination bias in qualitative research could occur to explore approaches for reducing it. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. A RETROSPECTIVE APPROACH REGARDING COMMERCIAL PERFORMANCES AND THE BALANCE SHEET INDICATORS OF MAIN ROMANIAN BANKS

    Directory of Open Access Journals (Sweden)

    Mihaela Nicolau

    2008-05-01

    Full Text Available In the context of the present financial crisis, a rigorously analysis of national and international bankingsystems during the crisis’ previous periods could lead to specific weaknesses that were not considered at theirreal importance at that time. The paper presents only a comparing analysis, during the period of three years(2004 – 2006, regarding the commercial performances and the main balance sheet indicators of two of the mostimportant and influence banks from Romanian banking system, respectively Romanian Commercial Bank(B.C.R and Development Romanian Bank – Group Société Générale (B.R.D. – SGThis analysis is included in an extensive study regarding the activity performances of the two Romanianbanks mentioned before.

  9. Residential-commercial energy input estimation based on genetic algorithm (GA) approaches: an application of Turkey

    International Nuclear Information System (INIS)

    Ozturk, H.K.; Canyurt, O.E.; Hepbasli, A.; Utlu, Z.

    2004-01-01

    The main objective of the present study is to develop the energy input estimation equations for the residential-commercial sector (RCS) in order to estimate the future projections based on genetic algorithm (GA) notion and to examine the effect of the design parameters on the energy input of the sector. For this purpose, the Turkish RCS is given as an example. The GA Energy Input Estimation Model (GAEIEM) is used to estimate Turkey's future residential-commercial energy input demand based on gross domestic product (GDP), population, import, export, house production, cement production and basic house appliances consumption figures. It may be concluded that the three various forms of models proposed here can be used as an alternative solution and estimation techniques to available estimation techniques. It is also expected that this study will be helpful in developing highly applicable and productive planning for energy policies. (author)

  10. Accounting Education Approach in the Context of New Turkish Commercial Code and Turkish Accounting Standards

    OpenAIRE

    Cevdet Kızıl; Ayşe Tansel Çetin; Ahmed Bulunmaz

    2014-01-01

    The aim of this article is to investigate the impact of new Turkish commercial code and Turkish accounting standards on accounting education. This study takes advantage of the survey method for gathering information and running the research analysis. For this purpose, questionnaire forms are distributed to university students personally and via the internet.This paper includes significant research questions such as “Are accounting academicians informed and knowledgeable on new Turkish commerc...

  11. Credit risk assessment model for Jordanian commercial banks: Neural scoring approach

    OpenAIRE

    Bekhet, Hussain Ali; Eletter, Shorouq Fathi Kamel

    2014-01-01

    Despite the increase in the number of non-performing loans and competition in the banking market, most of the Jordanian commercial banks are reluctant to use data mining tools to support credit decisions. Artificial neural networks represent a new family of statistical techniques and promising data mining tools that have been used successfully in classification problems in many domains. This paper proposes two credit scoring models using data mining techniques to support loan decisions for th...

  12. Commercial Space Transportation and Approaches to landing sites over Maritime Areas

    OpenAIRE

    Hesselink, Henk; Stevens, Jos; Nieuwenhuisen, Dennis; Schmitt, Dirk-Roger

    2015-01-01

    Commercial Space Transportation becomes an international business and requires landing opportunities all over the world. Hence the integration of space vehicles in other airspace than the US NAS is an important topic to be considered. The Single European Sky ATM Research Programme (SESAR) is preparing the implementation of a new ATM system in Europe. The requirements are defined by the concept of the shared Business Trajectory and System Wide Information Management (SWIM). Space vehicle op...

  13. Space commerce in a global economy - Comparison of international approaches to commercial space

    Science.gov (United States)

    Stone, Barbara A.; Kleber, Peter

    1992-01-01

    A historical perspective, current status, and comparison of national government/commercial space industry relationships in the United States and Europe are presented. It is noted that space technology has been developed and used primarily to meet the needs of civil and military government initiatives. Two future trends of space technology development include new space enterprises, and the national drive to achieve a more competitive global economic position.

  14. Commercial Aquaponics Approaching the European Market: To Consumers’ Perceptions of Aquaponics Products in Europe

    OpenAIRE

    Miličić, Vesna; Thorarinsdottir, Ragnheidur; Santos, Maria; Hančič, Maja

    2017-01-01

    The first commercial aquaponics companies are starting up in Europe. The main focus has been on solving technology issues and optimizing production. However, increasing attention is now being paid to certification and regulations linked to aquaponics, as well as the marketing of products and services. The paper presents the results of a study whose main aim was to estimate consumers’ knowledge about aquaponics and their acceptance of aquaponics products in different European regions. An on-li...

  15. High-throughput cryopreservation of spermatozoa of blue catfish (Ictalurus furcatus): Establishment of an approach for commercial-scale processing.

    Science.gov (United States)

    Hu, E; Yang, Huiping; Tiersch, Terrence R

    2011-02-01

    Hybrid catfish created by crossing of female channel catfish (Ictalurus punctatus) and male blue catfish (Ictalurus furcatus) are being used increasingly in foodfish aquaculture because of their fast growth and efficient food conversion. However, the availability of blue catfish males is limited, and their peak spawning is at a different time than that of the channel catfish. As such, cryopreservation of sperm of blue catfish could improve production of hybrid catfish, and has been studied in the laboratory and tested for feasibility in a commercial dairy bull cryopreservation facility. However, an approach for commercially relevant production of cryopreserved blue catfish sperm is still needed. The goal of this study was to develop practical approaches for commercial-scale sperm cryopreservation of blue catfish by use of an automated high-throughput system (MAPI, CryoBioSystem Co.). The objectives were to: (1) refine cooling rate and cryoprotectant concentration, and evaluate their interactions; (2) evaluate the effect of sperm concentration on cryopreservation; (3) refine cryoprotectant concentration based on the highest effective sperm concentration; (4) compare the effect of thawing samples at 20 or 40°C; (5) evaluate the fertility of thawed sperm at a research scale by fertilizing with channel catfish eggs; (6) test the post-thaw motility and fertility of sperm from individual males in a commercial setting, and (7) test for correlation of cryopreservation results with biological indices used for male evaluation. The optimal cooling rate was 5°C/min (Micro Digitcool, IMV) for high-throughput cryopreservation using CBS high-biosecurity 0.5-ml straws with 10% methanol, and a concentration of 1×10(9)sperm/ml. There was no difference in post-thaw motility when samples were thawed at 20°C for 40s or 40°C for 20s. After fertilization, the percentage of neurulation (Stage V embryos) was 80±21%, and percentage of embryonic mobility (Stage VI embryo) was 51±22

  16. Dissemination of CERN Technologies Through External Entrepreneurs

    CERN Document Server

    Lande, Bjørnulf Visdal; Huuse, Henning

    2008-01-01

    This study focuses on dissemination of innovations through external entrepreneurs. The innovations studied are developed at the European Organization for Nuclear Research (CERN) and commercialized by entrepreneurs establishing spin-off companies on the outside of the Organization. The objective of this study is to provide knowledge to facilitate future external entrepreneurs to increase dissemination of CERN technologies. The research questions looks at the timeline from preparations for creating the spin-off company, until having a product for commercialization in the market. A qualitative cross case investigation was conducted to assess the experiences of four spin-off companies. A framework was created to structure the discussion by finding and categorizing impeding- and success factors seen from the entrepreneurs point of view. The findings where structured in three phases respectively, the time before starting the company, the beginning of the company and the final development before selling products. Th...

  17. Different Analytical Approaches in Assessing Antibacterial Activity and the Purity of Commercial Lysozyme Preparations for Dairy Application

    Directory of Open Access Journals (Sweden)

    Luisa Pellegrino

    2013-05-01

    Full Text Available Hen egg-white lysozyme (LSZ is currently used in the food industry to limit the proliferation of lactic acid bacteria spoilage in the production of wine and beer, and to inhibit butyric acid fermentation in hard and extra hard cheeses (late blowing caused by the outgrowth of clostridial spores. The aim of this work was to evaluate how the enzyme activity in commercial preparations correlates to the enzyme concentration and can be affected by the presence of process-related impurities. Different analytical approaches, including turbidimetric assay, SDS-PAGE and HPLC were used to analyse 17 commercial preparations of LSZ marketed in different countries. The HPLC method adopted by ISO allowed the true LSZ concentration to be determined with accuracy. The turbidimetric assay was the most suitable method to evaluate LSZ activity, whereas SDS-PAGE allowed the presence of other egg proteins, which are potential allergens, to be detected. The analytical results showed that the purity of commercially available enzyme preparations can vary significantly, and evidenced the effectiveness of combining different analytical approaches in this type of control.

  18. Helix Nebula and CERN: A Symbiotic approach to exploiting commercial clouds

    Science.gov (United States)

    Barreiro Megino, Fernando H.; Jones, Robert; Kucharczyk, Katarzyna; Medrano Llamas, Ramón; van der Ster, Daniel

    2014-06-01

    The recent paradigm shift toward cloud computing in IT, and general interest in "Big Data" in particular, have demonstrated that the computing requirements of HEP are no longer globally unique. Indeed, the CERN IT department and LHC experiments have already made significant R&D investments in delivering and exploiting cloud computing resources. While a number of technical evaluations of interesting commercial offerings from global IT enterprises have been performed by various physics labs, further technical, security, sociological, and legal issues need to be address before their large-scale adoption by the research community can be envisaged. Helix Nebula - the Science Cloud is an initiative that explores these questions by joining the forces of three European research institutes (CERN, ESA and EMBL) with leading European commercial IT enterprises. The goals of Helix Nebula are to establish a cloud platform federating multiple commercial cloud providers, along with new business models, which can sustain the cloud marketplace for years to come. This contribution will summarize the participation of CERN in Helix Nebula. We will explain CERN's flagship use-case and the model used to integrate several cloud providers with an LHC experiment's workload management system. During the first proof of concept, this project contributed over 40.000 CPU-days of Monte Carlo production throughput to the ATLAS experiment with marginal manpower required. CERN's experience, together with that of ESA and EMBL, is providing a great insight into the cloud computing industry and highlighted several challenges that are being tackled in order to ease the export of the scientific workloads to the cloud environments.

  19. Helix Nebula and CERN: A Symbiotic approach to exploiting commercial clouds

    International Nuclear Information System (INIS)

    Megino, Fernando H Barreiro; Jones, Robert; Llamas, Ramón Medrano; Ster, Daniel van der; Kucharczyk, Katarzyna

    2014-01-01

    The recent paradigm shift toward cloud computing in IT, and general interest in 'Big Data' in particular, have demonstrated that the computing requirements of HEP are no longer globally unique. Indeed, the CERN IT department and LHC experiments have already made significant R and D investments in delivering and exploiting cloud computing resources. While a number of technical evaluations of interesting commercial offerings from global IT enterprises have been performed by various physics labs, further technical, security, sociological, and legal issues need to be address before their large-scale adoption by the research community can be envisaged. Helix Nebula – the Science Cloud is an initiative that explores these questions by joining the forces of three European research institutes (CERN, ESA and EMBL) with leading European commercial IT enterprises. The goals of Helix Nebula are to establish a cloud platform federating multiple commercial cloud providers, along with new business models, which can sustain the cloud marketplace for years to come. This contribution will summarize the participation of CERN in Helix Nebula. We will explain CERN's flagship use-case and the model used to integrate several cloud providers with an LHC experiment's workload management system. During the first proof of concept, this project contributed over 40.000 CPU-days of Monte Carlo production throughput to the ATLAS experiment with marginal manpower required. CERN's experience, together with that of ESA and EMBL, is providing a great insight into the cloud computing industry and highlighted several challenges that are being tackled in order to ease the export of the scientific workloads to the cloud environments.

  20. Business Process Improvement in Commercial Ship Division of PT. X: A Theory of Constraints Thinking Process Approach

    Directory of Open Access Journals (Sweden)

    Utario Esna Putra

    2013-03-01

    Full Text Available PT. X as one of the biggest shipyard is facing a great challenge to keep its existence. One of its division which has the largest production capacity and expected contribution, is Commercial Ship Division. At 2011 it only fulfilled 23,1% of its target, which brought a huge loss to the corporate. That condition presses Commercial Ship Division to manage a continuous improvement in business process. Facing a constrained resources, all effort must be effectively and efficiently carried on. In this research, solution in business process improvement is approached using Theory of Constraints Thinking Process. From Current Reality Tree (CRT diagram, the model of problem is acquired. Future Reality Tree (FRT diagram is used to depict how injection influence the improvement. Transition Tree (TT is assembled to arrange the necessary step for improvement or a road map.

  1. Commercialization as a recommended approach to hospital restructuring. Case study of Łańcut Medical Center

    Directory of Open Access Journals (Sweden)

    Wiktor Patena

    2015-10-01

    Full Text Available Our society is on the brink of health care system reorganization and implementation of new medical technology. Hospitals have to be a core component of the medical revolution so they have to be prepared for the upcoming leap in their development. If Poland wants to be a pioneer in providing new medical solutions, the current ineffective system has to be changed. The necessary action should be taken to deal with the financial problems Polish hospitals have faced for over 20 years. The current structure of hospitals - SPZOZ, is old-fashioned and cannot adapt to a turbulent social and economic environment. The hospitals should be commercialized and restructured. Being capitalized companies will give incentives and new tools to deal with financial problems. The article presents an example of the commercialized hospital in Łańcut. We make the observations that commercialization increases: a hospital’s profitability, its employment productivity, its capital investment spending and leverage. The case proves that the transformation of hospitals to capital companies proposed by the Ministry of Health may be an appropriate approach and it does work once a reasonable management board is in charge. However, the legal structure alteration should be treated as the first step in the overall restructuring process. The article highlights the problem of managers of Polish hospitals who do not only struggle with financial shortages, but barely know which business model they should follow after commercialization to successfully run the restructuring process. Having examined the LMC the authors are crafting a prelude to the overall research on already commercialized hospitals to find an appropriate business model.

  2. Assessing the authenticity of commercial deep-sea drinking water by chemical and isotopic approaches.

    Science.gov (United States)

    Peng, Tsung-Ren; Liang, Wen-Jui; Liu, Tsang-Sen; Lin, Yu-Wen; Zhan, Wen-Jun

    2015-01-01

    This study combines stable isotopes and chemical elements with statistical principal component analysis (PCA) to assess the authenticity of bottled commercial drinking water desalinized from deep seawater in the Taiwan market. Isotopic results indicate that true bottled deep-sea drinking water (DSDW) exhibits about 0 ‰ for both δ(2)H and δ(18)O values, which are values similar to those of open seawater. By comparison, suspected counterfeit DSDW products display δ(2)H and δ(18)O values of around -51 ‰ and -8 ‰, respectively. These values are representative of terrestrial freshwater. In addition, suspected counterfeit DSDWs have δ and electrical conductivity values similar to a mixed water (MW) product that was manufactured by purifying terrestrial freshwater and adulterating this with small amounts of brine. Furthermore, PCA results indicate the chemical constitution of suspected DSDW products to be similar to the MW product which falls between purified terrestrial freshwater and desalinized open seawater. These similarities imply that suspected counterfeit DSDW products are manufactured in a similar manner to the declared MW product. This study demonstrates how combining knowledge of stable water isotopes and PCA can be used in assessing the authenticity of commercial DSDW products. The method should be of great interest to similar investigations elsewhere.

  3. Fat, oil and grease reduction in commercial kitchen ductwork: A novel biological approach.

    Science.gov (United States)

    Mudie, S; Vahdati, M

    2017-03-01

    Recent research has characterised emissions upon cooking a variety of foods in a commercial catering environment in terms of volume, particle size and composition. However, there has been limited focus on the deposition of solid grease in commercial kitchen ductwork, the sustainability of these systems and their implications on the heat recovery potential of kitchen ventilation extract air. This paper reviews the literature concerning grease, commonly referred to as Fat, Oils and Grease (FOG) abatement strategies and finds that many of these systems fall short of claimed performances. Furthermore these technologies often add to the energy cost of the operation and reduce the potential application of heat recovery in the ventilation ductwork. The aim of this study was to develop and evaluate a novel FOG removal system, with a focus on low environmental impact. The novel FOG removal system, utilises the biological activity of Bacillus subtilis and associated enzymes. The biological reagent is delivered via a misting system. The temperature, relative humidity and FOG deposit thickness were measured in the ductwork throughout a 3month trial period. FOG deposit thickness was reduced by 47% within 7weeks. The system was found to be effective at reducing the FOG deposit thickness with minimal energy cost and impact upon the kitchen and external environment. Internal ductwork operating temperature was measured with respect to future heat recovery potential and a reduction of 7°C was observed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. A step-by-step approach to improve data quality when using commercial business lists to characterize retail food environments.

    Science.gov (United States)

    Jones, Kelly K; Zenk, Shannon N; Tarlov, Elizabeth; Powell, Lisa M; Matthews, Stephen A; Horoi, Irina

    2017-01-07

    Food environment characterization in health studies often requires data on the location of food stores and restaurants. While commercial business lists are commonly used as data sources for such studies, current literature provides little guidance on how to use validation study results to make decisions on which commercial business list to use and how to maximize the accuracy of those lists. Using data from a retrospective cohort study [Weight And Veterans' Environments Study (WAVES)], we (a) explain how validity and bias information from existing validation studies (count accuracy, classification accuracy, locational accuracy, as well as potential bias by neighborhood racial/ethnic composition, economic characteristics, and urbanicity) were used to determine which commercial business listing to purchase for retail food outlet data and (b) describe the methods used to maximize the quality of the data and results of this approach. We developed data improvement methods based on existing validation studies. These methods included purchasing records from commercial business lists (InfoUSA and Dun and Bradstreet) based on store/restaurant names as well as standard industrial classification (SIC) codes, reclassifying records by store type, improving geographic accuracy of records, and deduplicating records. We examined the impact of these procedures on food outlet counts in US census tracts. After cleaning and deduplicating, our strategy resulted in a 17.5% reduction in the count of food stores that were valid from those purchased from InfoUSA and 5.6% reduction in valid counts of restaurants purchased from Dun and Bradstreet. Locational accuracy was improved for 7.5% of records by applying street addresses of subsequent years to records with post-office (PO) box addresses. In total, up to 83% of US census tracts annually experienced a change (either positive or negative) in the count of retail food outlets between the initial purchase and the final dataset. Our study

  5. Disseminated histoplasmosis in infants.

    Science.gov (United States)

    Odio, C M; Navarrete, M; Carrillo, J M; Mora, L; Carranza, A

    1999-12-01

    Disseminated histoplasmosis usually occurs in immunocompromised patients who reside in Histoplasma capsulatum-endemic regions. It has also been described in immunocompetent infants after exposure to a large inoculum of the pathogen resulting in case fatality rates of 40 to 50%. From 1983 through 1996 all infants with documented disseminated histoplasmosis were treated with amphotericin B followed by daily ketoconazole for 3 months. Immunologic workups were performed at the time of diagnosis and at 4 to 6 weeks of therapy. Surviving patients were followed for at least 1 year. Time to resolution of signs and symptoms was recorded, as were complications. We managed 40 patients with disseminated histoplasmosis. The age in months at diagnosis was 15.3+/-10.2 (mean +/- SD), and 24 were male. All patients were from endemic regions and they presented with fever, spleen and/or liver enlargement and hematologic abnormalities. Diagnosis was made by histology and culture of bone marrow, spleen, lymph node, bronchoalveolar or liver samples. Twenty patients presented with T cell deficiency that resolved at 4 to 6 weeks of therapy in all of the retested patients, and 10 of 12 tested patients had hyperglobulinemia that resolved. Thirty-five (88%) patients were cured by treatment; 4 died and 1 relapsed. Disseminated histoplasmosis should be considered in infants from endemic areas who present with fever, hepatosplenomegaly and hematologic abnormalities. These patients develop transient hyperglobulinemia and T cell deficiency that resolve with treatment. Treatment with amphotericin B followed by an oral azole for 3 months is effective in most patients.

  6. Acute disseminated cutaneous candidiasis.

    Science.gov (United States)

    Fong, P H; Chan, H L; Lee, Y S; Wong, H B

    1988-10-01

    Acute disseminated candidiasis is a serious and difficult problem often seen in immunocompromised states. Appearance of a characteristic skin eruption is helpful in the diagnostic. We report below a case report of an eight year old girl with aplastic anemia who had received multiple courses of antibiotics. A profuse monomorphic papular nodular eruption subsequently appeared on the face, palms and soles. Candida tropicalis was identified from the skin biopsy taken from one such lesion.

  7. Disseminated malignant melanoma

    Directory of Open Access Journals (Sweden)

    Verma Kaushal

    1999-01-01

    Full Text Available A 25-year-old man had multiple asymptomatic, nodular lesions on the trunk, extremities and the face for 3 months. He also had left facial palsy with severe headache and vomiting. There were no other systemic or constitutional symptoms. Skin biopsy from a nodular lesion showed features of malignant melanoma, confirmed by Fontana Masson and S-100 protein staining. A diagnosis of disseminated malignant melanoma was made and the patient was treated symptomatically. The patient died in 4 months.

  8. New liquid chromatographic-chemometric approach for the determination of sunset yellow and tartrazine in commercial preparation.

    Science.gov (United States)

    Dinç, Erdal; Aktaş, A Hakan; Ustündağ, Ozgür

    2005-01-01

    A new liquid chromatographic (LC)-chemometric approach was developed for the determination of sunset yellow (SUN) and tartrazine (TAR) in commercial preparations. This approach uses LC and chemometric calibration methods, i.e., classical least-squares (CLS), principal component regression (PCR), and partial-least squares (PLS), simultaneously. The combined LC-chemometric approaches, denoted as LC-CLS, LC-PCR, and LC-PLS, are based on photodiode array (PDA) detection at multiple wavelengths. Optimum chromatographic separation of SUN and TAR with allura red as the internal standard (IS) was obtained by using a Waters Symmetry C18 column, 5 microm, 4.6 x 250 mm, and 0.2 M acetate buffer (pH 5)-acetonitrile-methano-bidistilled water (55 + 20 + 15 + 10, v/v) as the mobile phase at a flow rate of 1.9 mL/min. The LC data sets consisting of the ratios of analyte peak areas to the IS peak area were obtained by using PDA detection at 5 wavelengths (465, 470, 475, 480, and 485 nm). LC-chemometric calibrations for SUN and TAR were separately constructed by using the relationship between the peak-area ratio and the training sets for each colorant. LC-chemometric approaches were tested for different synthetic mixtures containing SUN and TAR in the presence of the IS. These LC-chemometric calibrations were applied to a commercial preparation of the 2 colorants. The experimental results of the LC-chemometric approaches were compared with those obtained by a developed classical LC method using single-wavelength detection.

  9. Dissemination and Exploitation: Project Goals beyond Science

    Science.gov (United States)

    Hamann, Kristin; Reitz, Anja

    2017-04-01

    Dissemination and Exploitation are essential parts of public funded projects. In Horizon 2020 a plan for the exploitation and dissemination of results (PEDR) is a requirement. The plan should contain a clear vision on the objectives of the project in relation to actions for dissemination and potential exploitation of the project results. The actions follow the basic idea to spread the knowledge and results gathered within the project and face the challenge of how to bring the results into potentially relevant policy circle and how they impact the market. The plan follows the purpose to assess the impact of the project and to address various target groups who are interested in the project results. Simply put, dissemination concentrates on the transfer of knowledge and exploitation on the commercialization of the project. Beyond the question of the measurability of project`s impact, strategies within science marketing can serve purposes beyond internal and external communication. Accordingly, project managers are facing the challenge to implement a dissemination and exploitation strategy that ideally supports the identification of all partners with the project and matches the current discourse of the project`s content within the society, politics and economy. A consolidated plan might unite all projects partners under a central idea and supports the identification with the project beyond the individual research questions. Which applications, strategies and methods can be used to bring forward a PEDR that accompanies a project successfully and allows a comprehensive assessment of the project afterwards? Which hurdles might project managers experience in the dissemination process and which tasks should be fulfilled by the project manager?

  10. Approaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin.

    Science.gov (United States)

    Kung, Stephanie H; Lund, Sean; Murarka, Abhishek; McPhee, Derek; Paddon, Chris J

    2018-01-01

    The antimalarial drug artemisinin is a natural product produced by the plant Artemisia annua . Extracts of A. annua have been used in Chinese herbal medicine for over two millennia. Following the re-discovery of A. annua extract as an effective antimalarial, and the isolation and structural elucidation of artemisinin as the active agent, it was recommended as the first-line treatment for uncomplicated malaria in combination with another effective antimalarial drug (Artemisinin Combination Therapy) by the World Health Organization (WHO) in 2002. Following the WHO recommendation, the availability and price of artemisinin fluctuated greatly, ranging from supply shortfalls in some years to oversupply in others. To alleviate these supply and price issues, a second source of artemisinin was sought, resulting in an effort to produce artemisinic acid, a late-stage chemical precursor of artemisinin, by yeast fermentation, followed by chemical conversion to artemisinin (i.e., semi-synthesis). Engineering to enable production of artemisinic acid in yeast relied on the discovery of A. annua genes encoding artemisinic acid biosynthetic enzymes, and synthetic biology to engineer yeast metabolism. The progress of this effort, which resulted in semi-synthetic artemisinin entering commercial production in 2013, is reviewed with an emphasis on recent publications and opportunities for further development. Aspects of both the biology of artemisinin production in A. annua , and yeast strain engineering are discussed, as are recent developments in the chemical conversion of artemisinic acid to artemisinin.

  11. Adopting an Evidence-Based Lifestyle Physical Activity Program: Dissemination Study Design and Methods.

    Science.gov (United States)

    Dunn, Andrea L; Buller, David B; Dearing, James W; Cutter, Gary; Guerra, Michele; Wilcox, Sara; Bettinghaus, Erwin P

    2012-06-01

    BACKGROUND: There is a scarcity of research studies that have examined academic-commercial partnerships to disseminate evidence-based physical activity programs. Understanding this approach to dissemination is essential because academic-commercial partnerships are increasingly common. Private companies have used dissemination channels and strategies to a degree that academicians have not, and declining resources require academicians to explore these partnerships. PURPOSE: This paper describes a retrospective case-control study design including the methods, demographics, organizational decision-making, implementation rates, and marketing strategy for Active Living Every Day (ALED), an evidence-based lifestyle physical activity program that has been commercially available since 2001. Evidence-based public health promotion programs rely on organizations and targeted sectors to disseminate these programs although relatively little is known about organizational-level and sector-level influences that lead to their adoption and implementation. METHODS: Cases (n=154) were eligible if they had signed an ALED license agreement with Human Kinetics (HK), publisher of the program's textbooks and facilitator manuals, between 2001 and 2008. Two types of controls were matched (2:2:1) and stratified by sector and region. Active controls (Control 1; n=319) were organizations that contacted HK to consider adopting ALED. Passive controls (Control 2; n=328) were organizations that received unsolicited marketing materials and did not initiate contact with HK. We used Diffusion of Innovations Theory (DIT) constructs as the basis for developing the survey of cases and controls. RESULTS: Using the multi-method strategy recommended by Dillman, a total of n=801 cases and controls were surveyed. Most organizations were from the fitness sector followed by medical, nongovernmental, governmental, educational, worksite and other sectors with significantly higher response rates from government

  12. Indonesia knowledge dissemination: a snapshot

    Science.gov (United States)

    Nasution, M. K. M.

    2018-03-01

    The educational progress of a country or educational institution is measured through the implementation of knowledge dissemination. Evidence of knowledge dissemination has carried out be in form of the type of published document, which is based on the databases of the index of scientific publications: Scopus. This paper expresses a simple form of knowledge dissemination based on document type. Although the growth of knowledge dissemination does not have the same pattern based on the appearance of document types, the general implementation is almost the same. However, maximum effort needs to be done by PTN-bh to support Indonesia knowledge dissemination.

  13. License stewardship and other approaches to commercial nuclear power plant decommissioning

    International Nuclear Information System (INIS)

    Daly, P.T.; Moloney, B.P.

    2011-01-01

    This paper addresses the challenge of how our industry could arrange itself to deliver decommissioning of Nuclear Power Plants (NPPs) safely, in good time and affordably. There is a growing wealth of experience across the world in safe decommissioning techniques. Most - arguably all - of the techniques required to perform the full decommissioning of NPPs have been demonstrated on full-scale projects. Waste processing and disposal challenges remain in many countries, where the major issues are societal acceptance and political will. Interim storage possibilities have been identified in most countries. In decommissioning, the outstanding significant issues lie now in the domain of affordability and risk management. This paper will illustrate approaches to decommissioning with examples from the US and UK, to explore how the industry can achieve configurations to deliver lower risk and improved affordability for utilities. Different configurations, or models, will be used to illustrate the approaches taken. (orig.)

  14. Why social entrepreneurship? Public and commercial, dual-approach for social enterprises with Chinese cases

    OpenAIRE

    Xu, Husheng; Song, Xiaoyan; Song, Wei

    2014-01-01

    Social entrepreneurship or enterprise is considered as an innovative form, which combines economic and social value creation to improve societal development. Theory and practice of this field are attracting more attention. In this article, we identified significant literature and journals as well as academic citation relationships for advancing scholarly research on social entrepreneurship. Then, we established a dual-approach for social entrepreneurship with China's cases: public and commerc...

  15. Ranking and selection of commercial off-the-shelf using fuzzy distance based approach

    Directory of Open Access Journals (Sweden)

    Rakesh Garg

    2015-06-01

    Full Text Available There is a tremendous growth of the use of the component based software engineering (CBSE approach for the development of software systems. The selection of the best suited COTS components which fulfils the necessary requirement for the development of software(s has become a major challenge for the software developers. The complexity of the optimal selection problem increases with an increase in alternative potential COTS components and the corresponding selection criteria. In this research paper, the problem of ranking and selection of Data Base Management Systems (DBMS components is modeled as a multi-criteria decision making problem. A ‘Fuzzy Distance Based Approach (FDBA’ method is proposed for the optimal ranking and selection of DBMS COTS components of an e-payment system based on 14 selection criteria grouped under three major categories i.e. ‘Vendor Capabilities’, ‘Business Issues’ and ‘Cost’. The results of this method are compared with other Analytical Hierarchy Process (AHP which is termed as a typical multi-criteria decision making approach. The proposed methodology is explained with an illustrated example.

  16. Establishing a Commercial Buildings Energy Data Framework for India: A Comprehensive Look at Data Collection Approaches, Use Cases and Institutions

    Energy Technology Data Exchange (ETDEWEB)

    Iyer, Maithili [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kumar, Satish [Synurja, LLC, Vienna, VA (United States); Mathew, Sangeeta [Synurja, LLC, Vienna, VA (United States); Stratton, Hannah [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mathew, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Singh, Mohini [Synurja, LLC, Vienna, VA (United States)

    2016-10-01

    Enhancing energy efficiency of the commercial building stock is an important aspect of any national energy policy. Understanding how buildings use energy is critical to formulating any new policy that may impact energy use, underscoring the importance of credible data. Data enables informed decision making and good quality data is essential for policy makers to prioritize energy saving strategies and track implementation. Given the uniqueness of the buildings sector and challenges to collecting relevant energy data, this study characterizes various elements involved in pertinent data collection and management, with the specific focus on well-defined data requirements, appropriate methodologies and processes, feasible data collection mechanisms, and approaches to institutionalizing the collection process. This report starts with a comprehensive review of available examples of energy data collection frameworks for buildings across different countries. The review covers the U.S. experience in the commercial buildings sector, the European experience in the buildings sector and other data collection initiatives in Singapore and China to capture the more systematic efforts in Asia in the commercial sector. To provide context, the review includes a summary and status of disparate efforts in India to collect and use commercial building energy data. Using this review as a key input, the study developed a data collection framework for India with specific consideration to relevant use cases. Continuing with the framework for data collection, this study outlines the key performance indicators applicable to the use cases and their collection feasibility, as well as immediate priorities of the participating stakeholders. It also discusses potential considerations for data collection and the possible approaches for survey design. With the specific purpose of laying out the possible ways to structure and organize data collection institutionally, the study collates existing

  17. Delusions of Disseminated Fungosis

    Directory of Open Access Journals (Sweden)

    Ian Gassiep

    2014-01-01

    Full Text Available Introduction. Delusional infestation is a rare monosymptomatic hypochondriacal psychosis according to The Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association, 2013. It can be a primary disorder or associated with an underlying psychological or physical disorder. It commonly presents as delusional parasitosis, and less than 1% may be fungi related. We present this case as it is a rare presentation of a rare condition. Case Presentation. Our patient is a 60-year-old Caucasian man who presented with a 7-year history of delusional infestation manifested as a disseminated fungal infection. He had previously been reviewed by multiple physicians for the same with no systemic illness diagnosed. After multiple reviews and thorough investigation we diagnosed him with a likely delusional disorder. As is common with this patient cohort he refused psychiatric review or antipsychotic medication. Conclusion. A delusion of a disseminated fungal infestation is a rare condition. It is exceedingly difficult to treat as these patients often refuse to believe the investigation results and diagnosis. Furthermore, they either refuse or are noncompliant with treatment. Multidisciplinary outpatient evaluation may be the best way to allay patient fears and improve treatment compliance.

  18. Asymmetric connectivity of spawning aggregations of a commercially important marine fish using a multidisciplinary approach

    Directory of Open Access Journals (Sweden)

    Adrian Munguia-Vega

    2014-08-01

    Full Text Available Understanding patterns of larval dispersal is key in determining whether no-take marine reserves are self-sustaining, what will be protected inside reserves and where the benefits of reserves will be observed. We followed a multidisciplinary approach that merged detailed descriptions of fishing zones and spawning time at 17 sites distributed in the Midriff Island region of the Gulf of California with a biophysical oceanographic model that simulated larval transport at Pelagic Larval Duration (PLD 14, 21 and 28 days for the most common and targeted predatory reef fish, (leopard grouper Mycteroperca rosacea. We tested the hypothesis that source–sink larval metapopulation dynamics describing the direction and frequency of larval dispersal according to an oceanographic model can help to explain empirical genetic data. We described modeled metapopulation dynamics using graph theory and employed empirical sequence data from a subset of 11 sites at two mitochondrial genes to verify the model predictions based on patterns of genetic diversity within sites and genetic structure between sites. We employed a population graph describing a network of genetic relationships among sites and contrasted it against modeled networks. While our results failed to explain genetic diversity within sites, they confirmed that ocean models summarized via graph and adjacency distances over modeled networks can explain seemingly chaotic patterns of genetic structure between sites. Empirical and modeled networks showed significant similarities in the clustering coefficients of each site and adjacency matrices between sites. Most of the connectivity patterns observed towards downstream sites (Sonora coast were strictly asymmetric, while those between upstream sites (Baja and the Midriffs were symmetric. The best-supported gene flow model and analyses of modularity of the modeled networks confirmed a pulse of larvae from the Baja Peninsula, across the Midriff Island region

  19. A confirmatory research approach to the measurement of EMI/RFI in commercial nuclear power plants

    International Nuclear Information System (INIS)

    Kercel, S.W.

    1995-01-01

    The Oak Ridge National Laboratory (ORNL) is conducting confirmatory research on the measurement of electromagnetic/radio frequency interference (EMI/RFI) in nuclear power plants while it makes a good beginning, the currently available research data are not sufficient to characterize the EMI/RFI environment of the typical nuclear plant. Data collected over several weeks at each of several observation points are required to meet this need. To collect the required data, several approaches are examined, the most promising of which is the relatively new technology of application specific spectral receivers. While several spectral receiver designs have been described in the literature, none is well suited for nuclear power plant EMI/RFI surveys. This paper describes the development of two receivers specifically designed for nuclear power plant EMI/RFI surveys. One receiver surveys electric fields between 5 MHz and 8 GHz, while the other surveys magnetic fields between 305 Hz and 5 MHz. The results of field tests at TVA's Bull Run Fossil Plant are reported

  20. A confirmatory research approach to the measurement of EMI/RFI in commercial nuclear power plants

    International Nuclear Information System (INIS)

    Kercel, S.W.

    1995-01-01

    The Oak Ridge National Laboratory (ORNL) is conducting confirmatory research on the measurement of electromagnetic/radio frequency interference (EMI/RFI) in nuclear power plants. While it makes a good beginning, the currently available research data are not sufficient to characterize the EMI/RFI environment of the typical nuclear plant. Data collected over several weeks at each of several observation points are required to meet this need. To collect the required data, several approaches are examined, the most promising of which is the relatively new technology of application specific spectral receivers. While several spectral receiver designs have been described in the literature, none is well suited for nuclear power plant EMI/RFI surveys. This paper describes the development of two receivers specifically designed for nuclear power plant EMI/RFI surveys. One receiver surveys electric fields between 5 MHz and 8 GHz, while the other surveys magnetic fields between 305 Hz and 5 MHz. The results of field tests at TVA's Bull Run Fossil Plant are reported

  1. Life cycle cost analysis of commercial buildings with energy efficient approach

    Directory of Open Access Journals (Sweden)

    Nilima N. Kale

    2016-09-01

    Full Text Available In any construction project, cost effectiveness plays a crucial role. The Life Cycle Cost (LCC analysis provides a method of determining entire cost of a structure over its expected life along with operational and maintenance cost. LCC can be improved by adopting alternative modern techniques without much alteration in the building. LCC effectiveness can be calculated at various stages of entire span of the building. Moreover this provides decision makers with the financial information necessary for maintaining, improving, and constructing facilities. Financial benefits associated with energy use can also be calculated using LCC analysis. In the present work, case study of two educational buildings has been considered. The LCC of these buildings has been calculated with existing condition and with proposed energy efficient approach (EEA using net present value method. A solar panel having minimum capacity as well as solar panel with desired capacity as per the requirements of the building has been suggested. The comparison of LCC of existing structure with proposed solar panel system shows that 4% of cost can be reduced in case of minimum capacity solar panel and 54% cost can be reduced for desired capacity solar panel system, along with other added advantages of solar energy.

  2. An exploration of factors related to dissemination of and exposure to internet-delivered behavior change interventions aimed at adults: a Delphi study approach.

    Science.gov (United States)

    Brouwer, Wendy; Oenema, Anke; Crutzen, Rik; de Nooijer, Jascha; de Vries, Nanne K; Brug, Johannes

    2008-04-16

    strategies, like word-of-mouth by family and friends, a publicity campaign with simultaneous use of various mass media, and recommendation by health professionals, were indicated as effective ways to encourage adults to visit an Internet intervention. This systematic study identified important factors related to the dissemination of and exposure to Internet interventions aimed at adults. In order to improve optimal use of and exposure to Internet interventions, potential users may need to be motivated to visit such an intervention and the information provided needs to be personally relevant. Furthermore, several (technical) aspects of the intervention itself need to be taken into account when developing Internet interventions.

  3. Everywhere in Japan: an international approach to working with commercial gay businesses in HIV prevention.

    Science.gov (United States)

    Sherriff, Nigel; Koerner, Jane; Kaneko, Noriyo; Shiono, Satoshi; Takaku, Michiko; Boseley, Ross; Ichikawa, Seiichi

    2017-06-01

    In the UK and Japan, there is concern regarding rising rates of annual new HIV infections among Men who have Sex with Men (MSM). Whilst in the UK and Europe, gay businesses are increasingly recognized as being important settings through which to deliver HIV prevention and health promotion interventions to target vulnerable populations; in Japan such settings-based approaches are relatively underdeveloped. This article draws on qualitative data from a recently completed study conducted to explore whether it is feasible, acceptable and desirable to build on the recent European Everywhere project for adaptation and implementation in Japan. A series of expert workshops were conducted in Tokyo, Nagoya and Osaka with intersectoral representatives from Japanese and UK non-governmental organizations (NGOs), gay businesses, universities and gay communities (n = 46). Further discussion groups and meetings were held with NGO members and researchers from the Japanese Ministry of Health, Labour and Welfare's Research Group on HIV Prevention Policy, Programme Implementation and Evaluation among MSM (n = 34). The results showed that it is desirable, feasible and acceptable to adapt and implement a Japanese version of Everywhere. Such a practical, policy-relevant, settings-based HIV prevention framework for gay businesses may help to facilitate the necessary scale up of prevention responses among MSM in Japan. Given the high degree of sexual mobility between countries in Asia, there is considerable potential for the Everywhere Project (or its Japanese variant) to be expanded and adapted to other countries within the Asia-Pacific region. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. AIDS defining disease: Disseminated cryptococcosis

    Directory of Open Access Journals (Sweden)

    Roshan Anupama

    2006-01-01

    Full Text Available Disseminated cryptococcosis is one of the acquired immune deficiency syndrome defining criteria and the most common cause of life threatening meningitis. Disseminated lesions in the skin manifest as papules or nodules that mimic molluscum contagiosum (MC. We report here a human immunodeficiency virus positive patient who presented with MC like lesions. Disseminated cryptococcosis was confirmed by India ink preparation and histopathology. The condition of the patient improved with amphotercin B.

  5. "Trust Me--I'll Deliver": Acquisition Approaches to Guarantee Commercial Companies Deliver Critical Space Products in Time of Crisis

    National Research Council Canada - National Science Library

    Denker, Stephen

    1998-01-01

    .... However, over the last ten years, the US military has begun to rely on commercially available products to meet many of its requirements in a variety of sectors including the commercial space sector...

  6. Evolution of diffusion and dissemination theory.

    Science.gov (United States)

    Dearing, James W

    2008-01-01

    The article provides a review and considers how the diffusion of innovations Research paradigm has changed, and offers suggestions for the further development of this theory of social change. Main emphases of diffusion Research studies are compared over time, with special attention to applications of diffusion theory-based concepts as types of dissemination science. A considerable degree of paradigmatic evolution is observed. The classical diffusion model focused on adopter innovativeness, individuals as the locus of decision, communication channels, and adoption as the primary outcome measures in post hoc observational study designs. The diffusion systems in question were centralized, with fidelity of implementation often assumed. Current dissemination Research and practice is better characterized by tests of interventions that operationalize one or more diffusion theory-based concepts and concepts from other change approaches, involve complex organizations as the units of adoption, and focus on implementation issues. Foment characterizes dissemination and implementation Research, Reflecting both its interdisciplinary Roots and the imperative of spreading evidence-based innovations as a basis for a new paradigm of translational studies of dissemination science.

  7. Field approach to mining-dump revegetation by application of sewage sludge co-compost and a commercial biofertilizer.

    Science.gov (United States)

    Sevilla-Perea, A; Mingorance, M D

    2015-08-01

    An approach was devised for revegetation of a mining dump soil, sited in a semiarid region, with basic pH as well as Fe and Mn enrichment. A field experiment was conducted involving the use of co-compost (a mixture of urban sewage sludge and plant remains) along with a commercial biofertilizer (a gel suspension which contains arbuscular mycorrhizal fungus) to reinforce the benefits of the former. Four treatments were studied: unamended soil; application of conditioners separately and in combination. Pistachio, caper, rosemary, thyme and juniper were planted. We evaluated the effects of the treatments using soil quality (physicochemical properties, total content of hazardous elements, nutrient availability, microbial biomass and enzyme activities) and plant establishment indicators (survival, growth, vigor, nutrient content in leaves, nutrient balances and mycorrhizal root colonization). Thyme and juniper did not show a suitable survival rate (biofertilizer + co-compost > co-compost > biofertilizer > unamended. The application of co-compost was therefore essential with regard to improving soil fertility; furthermore, it increased leaf N and P content, whereas leaf Fe and Mn concentrations showed a decrease. The combined treatment, however, provided the best results. The positive interaction between the two soil conditioners might be related to the capacity of the biofertilizer to increase nutrient uptake from the composted residue, and to protect plants against Fe and Mn toxicity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. The sequence coding and search system: An approach for constructing and analyzing event sequences at commercial nuclear power plants

    International Nuclear Information System (INIS)

    Mays, G.T.

    1989-04-01

    The US Nuclear Regulatory Commission (NRC) has recognized the importance of the collection, assessment, and feedstock of operating experience data from commercial nuclear power plants and has centralized these activities in the Office for Analysis and Evaluation of Operational Data (AEOD). Such data is essential for performing safety and reliability analyses, especially analyses of trends and patterns to identify undesirable changes in plant performance at the earliest opportunity to implement corrective measures to preclude the occurrences of a more serious event. One of NRC's principal tools for collecting and evaluating operating experience data is the Sequence Coding and Search System (SCSS). The SCSS consists of a methodology for structuring event sequences and the requisite computer system to store and search the data. The source information for SCSS is the Licensee Event Report (LER), which is a legally required document. This paper describes the objective SCSS, the information it contains, and the format and approach for constructuring SCSS event sequences. Examples are presented demonstrating the use SCSS to support the analysis of LER data. The SCSS contains over 30,000 LERs describing events from 1980 through the present. Insights gained from working with a complex data system from the initial developmental stage to the point of a mature operating system are highlighted

  9. Is Model-Based Development a Favorable Approach for Complex and Safety-Critical Computer Systems on Commercial Aircraft?

    Science.gov (United States)

    Torres-Pomales, Wilfredo

    2014-01-01

    A system is safety-critical if its failure can endanger human life or cause significant damage to property or the environment. State-of-the-art computer systems on commercial aircraft are highly complex, software-intensive, functionally integrated, and network-centric systems of systems. Ensuring that such systems are safe and comply with existing safety regulations is costly and time-consuming as the level of rigor in the development process, especially the validation and verification activities, is determined by considerations of system complexity and safety criticality. A significant degree of care and deep insight into the operational principles of these systems is required to ensure adequate coverage of all design implications relevant to system safety. Model-based development methodologies, methods, tools, and techniques facilitate collaboration and enable the use of common design artifacts among groups dealing with different aspects of the development of a system. This paper examines the application of model-based development to complex and safety-critical aircraft computer systems. Benefits and detriments are identified and an overall assessment of the approach is given.

  10. The sequence coding and search system: an approach for constructing and analyzing event sequences at commercial nuclear power plants

    International Nuclear Information System (INIS)

    Mays, G.T.

    1990-01-01

    The U.S. Nuclear Regulatory Commission (NRC) has recognized the importance of the collection, assessment, and feedback of operating experience data from commercial nuclear power plants and has centralized these activities in the Office for Analysis and Evaluation of Operational Data (AEOD). Such data is essential for performing safety and reliability analyses, especially analyses of trends and patterns to identify undesirable changes in plant performance at the earliest opportunity to implement corrective measures to preclude the occurrence of a more serious event. One of NRC's principal tools for collecting and evaluating operating experience data is the Sequence Coding and Search System (SCSS). The SCSS consists of a methodology for structuring event sequences and the requisite computer system to store and search the data. The source information for SCSS is the Licensee Event Report (LER), which is a legally required document. This paper describes the objectives of SCSS, the information it contains, and the format and approach for constructing SCSS event sequences. Examples are presented demonstrating the use of SCSS to support the analysis of LER data. The SCSS contains over 30,000 LERs describing events from 1980 through the present. Insights gained from working with a complex data system from the initial developmental stage to the point of a mature operating system are highlighted. Considerable experience has been gained in the areas of evolving and changing data requirements, staffing requirements, and quality control and quality assurance procedures for addressing consistency, software/hardware considerations for developing and maintaining a complex system, documentation requirements, and end-user needs. Two other approaches for constructing and evaluating event sequences are examined including the Accident Precursor Program (ASP) where sequences having the potential for core damage are identified and analyzed, and the Significant Event Compilation Tree

  11. Concomitant disseminated histoplasmosis and disseminated tuberculosis after tumor necrosis factor inhibitor treatment: a case report.

    Science.gov (United States)

    Muñoz-Oca, Juan E; Villarreal Morales, Martha L; Nieves-Rodriguez, Aracelis; Martínez-Bonilla, Lemuel

    2017-01-13

    Tumor necrosis factor antagonist inhibitors have transformed the approach to patients with severe autoimmune conditions, such as rheumatoid arthritis. Although the therapy can be highly effective, TNF-α inhibitors are associated with an increased risk of opportunistic infections. Here, we report a case of concomitant disseminated histoplasmosis and tuberculosis in a 65-year-old female with rheumatoid arthritis treated with TNF-α inhibitor. Both conditions can be found in disseminated form in immunosuppressed hosts, but co-infection is rare with only a few cases having been reported, to our knowledge, all in HIV patients. This case posed a considerable challenge for diagnosis and treatment due to the unusual disseminated co-infection, the overlapping symptoms, and the interactions between medications.

  12. Herpes zoster (shingles) disseminated (image)

    Science.gov (United States)

    Herpes zoster (shingles) normally occurs in a limited area that follows a dermatome (see the "dermatome" picture). In individuals with damaged immune systems, herpes zoster may be widespread (disseminated), causing serious illness. ...

  13. Disseminated intravascular coagulation in sepsis

    NARCIS (Netherlands)

    Zeerleder, Sacha; Hack, C. Erik; Wuillemin, Walter A.

    2005-01-01

    Disseminated intravascular coagulation is a frequent complication of sepsis. Coagulation activation, inhibition of fibrinolysis, and consumption of coagulation inhibitors lead to a procoagulant state resulting in inadequate fibrin removal and fibrin deposition in the microvasculature. As a

  14. A High-Resolution Spatially Explicit Monte-Carlo Simulation Approach to Commercial and Residential Electricity and Water Demand Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Morton, April M [ORNL; McManamay, Ryan A [ORNL; Nagle, Nicholas N [ORNL; Piburn, Jesse O [ORNL; Stewart, Robert N [ORNL; Surendran Nair, Sujithkumar [ORNL

    2016-01-01

    Abstract As urban areas continue to grow and evolve in a world of increasing environmental awareness, the need for high resolution spatially explicit estimates for energy and water demand has become increasingly important. Though current modeling efforts mark significant progress in the effort to better understand the spatial distribution of energy and water consumption, many are provided at a course spatial resolution or rely on techniques which depend on detailed region-specific data sources that are not publicly available for many parts of the U.S. Furthermore, many existing methods do not account for errors in input data sources and may therefore not accurately reflect inherent uncertainties in model outputs. We propose an alternative and more flexible Monte-Carlo simulation approach to high-resolution residential and commercial electricity and water consumption modeling that relies primarily on publicly available data sources. The method s flexible data requirement and statistical framework ensure that the model is both applicable to a wide range of regions and reflective of uncertainties in model results. Key words: Energy Modeling, Water Modeling, Monte-Carlo Simulation, Uncertainty Quantification Acknowledgment This manuscript has been authored by employees of UT-Battelle, LLC, under contract DE-AC05-00OR22725 with the U.S. Department of Energy. Accordingly, the United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes.

  15. Disseminating genetically modified (GM) maize technology to ...

    African Journals Online (AJOL)

    Disseminating genetically modified (GM) maize technology to smallholder farmers in the Eastern Cape province of South Africa: extension personnel's awareness of stewardship requirements and dissemination practices.

  16. Dissemination 2.0 - the role of social media in research dissemination

    OpenAIRE

    Brandtzæg, Petter Bae

    2014-01-01

    Dissemination is defined as "the act of diffusing knowledge".  The traditional ways of research dissemination, is through the publications of papers and to attend conferences. Traditional dissemination is important, but not very accessible, transparent or visible.  However,  the principles and possibilities of disseminating research have changed with the introduction of social media – dissemination 2.0. Dissemination 2.0. is about researchers taking control over the dissemination process by t...

  17. D5.1 Dissemination Plan

    DEFF Research Database (Denmark)

    Buus, Lillian; Ryberg, Thomas; Eleftheriou, Paraskevi

    2009-01-01

    This deliverable describes the detailed dissemination plan of the EATrain2 consortium. It includes all important aspects of planned dissemination activities, defines dissemination phases and presents material and tools prepared in order to disseminate information on the EATrain2 solution. It aims...

  18. The Rise and Demise of Commercial Geography.

    Science.gov (United States)

    Handley, Lawrence R.

    1982-01-01

    Commercial geography, originally taught in 18th-century trading schools, reached its zenith in the mid-1920s because it was stimulated by the development of the British Empire, noted for its commercial applications, and popularized through information disseminated by geographical societies. Demise factors include America's isolationist attitudes,…

  19. Effectively Responding to the Commercial Sexual Exploitation of Children: A Comprehensive Approach to Prevention, Protection, and Reintegration Services.

    Science.gov (United States)

    Barnitz, Laura

    2001-01-01

    Discusses the international problem of commercial sexual exploitation of children (CSEC) and efforts to stop the practice and assist the victims. Considers initiatives to formulate a worldwide policy against CSEC, and anti-CSEC efforts in the United States, including law enforcement and education, and advocacy efforts and services for youth.…

  20. Social-Driven Information Dissemination for Mobile Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Basim MAHMOOD

    2015-06-01

    Full Text Available As we move into the so-called Internet of Things (IoT, the boundary between sensor networks and social networks is likely to disappear. Moreover, previous works argue that mobility in sensor networks may become a consequence of human movement making the understanding of human mobility crucial to the design of sensor networks. When people carry sensors, they become able to use concepts from social networks in the design of sensor network infrastructures. However, to this date, the utilization of social networks in designing protocols for wireless sensor networks has not received much attention. In this paper, we focus on the concept of information dissemination in a framework where sensors are carried by people who, like most of us, are part of a social network. We propose two social-based forwarding approaches for what has been called Social Network of Sensors (SNoS. To this end, we exploit two important characteristics of ties in social networks, namely strong ties and weak ties. The former is used to achieve rapid dissemination to nearby sensors while the latter aims at dissemination to faraway sensors. We compared our results against two well-known approaches in the literature: Epidemic and PRoPHET protocols. We evaluate our approaches according to four criteria: information-dissemination distance, information-dissemination coverage area, the number of messages exchanged, and information delivery time. We believe this is the first work that investigates the issues of information-dissemination distance and information-dissemination coverage area using an approach inspired on social network concepts.

  1. Disseminated hemangiosarcoma in a cow

    OpenAIRE

    Stock, Matthew L.; Smith, Billy I.; Engiles, Julie B.

    2011-01-01

    An antemortem diagnosis of disseminated hemangiosarcoma with extensive hepatic and splenic involvement was made in a 9-year-old cow evaluated for lethargy, weight loss, regenerative anemia, thrombocytopenia, and elevated liver enzymes. This is the first report of hemangiosarcoma in a cow with a suspected primary location of the liver and/or spleen.

  2. Disseminated hemangiosarcoma in a cow

    Science.gov (United States)

    Stock, Matthew L.; Smith, Billy I.; Engiles, Julie B.

    2011-01-01

    An antemortem diagnosis of disseminated hemangiosarcoma with extensive hepatic and splenic involvement was made in a 9-year-old cow evaluated for lethargy, weight loss, regenerative anemia, thrombocytopenia, and elevated liver enzymes. This is the first report of hemangiosarcoma in a cow with a suspected primary location of the liver and/or spleen. PMID:21731096

  3. The Commtech Methodology: A Demand-Driven Approach to Efficient, Productive, and Measurable Technology Transfer and Commercialization

    Science.gov (United States)

    Horsham, Gary A. P.

    1999-01-01

    This paper presents a comprehensive review and assessment of a demonstration technology transfer and commercialization prouram called "CommTech". The pro-ram was conceived and initiated in early to mid-fiscal year 1995, and extended roughly three years into the future. Market research sources were used to initially gather primary technological problems and needs data from non-aerospace companies in three targeted industry sectors: environmental, surface transportation, and bioengineering. Company-supplied information served as input data to activate or start-up an internal, phased matchmaking process. This process was based on technical-level relationship exploration followed by business-level agreement negotiations. and culminated with project management and execution. Space Act Agreements represented near-term outputs. Company product or process commercialization derived from NASA Glenn support and measurable economic effects represented far-term outputs.

  4. An integrated approach utilising chemometrics and GC/MS for classification of chamomile flowers, essential oils and commercial products.

    Science.gov (United States)

    Wang, Mei; Avula, Bharathi; Wang, Yan-Hong; Zhao, Jianping; Avonto, Cristina; Parcher, Jon F; Raman, Vijayasankar; Zweigenbaum, Jerry A; Wylie, Philip L; Khan, Ikhlas A

    2014-01-01

    As part of an ongoing research program on authentication, safety and biological evaluation of phytochemicals and dietary supplements, an in-depth chemical investigation of different types of chamomile was performed. A collection of chamomile samples including authenticated plants, commercial products and essential oils was analysed by GC/MS. Twenty-seven authenticated plant samples representing three types of chamomile, viz. German chamomile, Roman chamomile and Juhua were analysed. This set of data was employed to construct a sample class prediction (SCP) model based on stepwise reduction of data dimensionality followed by principle component analysis (PCA) and partial least squares discriminant analysis (PLS-DA). The model was cross-validated with samples including authenticated plants and commercial products. The model demonstrated 100.0% accuracy for both recognition and prediction abilities. In addition, 35 commercial products and 11 essential oils purported to contain chamomile were subsequently predicted by the validated PLS-DA model. Furthermore, tentative identification of the marker compounds correlated with different types of chamomile was explored. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. MRI in acute disseminated encephalomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Caldemeyer, K.S. (Div. of Neuroradiology, Dept. of Radiology, Indiana Univ. School of Medicine, Indianapolis, IN (United States)); Smith, R.R. (Div. of Neuroradiology, Dept. of Radiology, Indiana Univ. School of Medicine, Indianapolis, IN (United States)); Harris, T.M. (Div. of Neuroradiology, Dept. of Radiology, Indiana Univ. School of Medicine, Indianapolis, IN (United States)); Edwards, M.K. (Div. of Neuroradiology, Dept. of Radiology, Indiana Univ. School of Medicine, Indianapolis, IN (United States))

    1994-04-01

    A retrospective analysis of CT and MRI studies in 12 patients with a clinical diagnosis of acute disseminated encephalomyelitis (ADEM) was performed. MRI was the definitive modality for the assessment of the lesions of ADEM: all patients had abnormalities consistent with the clinical diagnosis. Ten had abnormalities in the brain, three spinal cord lesions, and three showed evidence of optic neuritis. CT was normal in 6 of the 7 patients in which it was performed. (orig.)

  6. System for the dissemination of innovative technological solutions at an R&D institute

    Directory of Open Access Journals (Sweden)

    Marzena Walasik

    2013-06-01

    Full Text Available The changes in the global market and the emphasis on the commercialization of R&D results, boost competitiveness and decide on the necessity to implement a marketing approach towards the organization and management of the business activity, including that of research institutions, which being treated as a unique kind of enterprises, make the results of their research commercially available. An important factor supporting effective commercialisation of research results is a proper preparation and execution of promotion activities, which based on the rules of marketing, increase the likelihood of success of implementation of innovative solutions on the market. The dissemination activities comprise all activities aimed at raising the interest of the public (i. e. users, enterprises, institutions in the results of R&D works, and focused on presenting the possibilities and benefits of their practical application. In order for the innovations to be diffused, target markets need to be specified, media most relevant for a given sector of the market need to be selected together with the most effective ways of reaching out to the target groups identified in the market segmentation process, and an effective marketing campaign needs to be launched. The system for the dissemination of innovative solutions developed and implemented at the Institute for Sustainable Technologies – National Research Institute in Radom (Poland (ITeE – PIB, supports the management of R&D results and stimulates networking between the Institute and entities involved in the practical implementation of innovations. It also enables the execution of system tasks concerning promotion of innovative product and process technologies developed at the ITeE – PIB. As a result of its application, business projects, which improve the technology commercialization process resulting in new products or technologies being brought to the market, are proposed.

  7. Water quality analysis of the commercial boreholes in Mubi Metropolis, Adamawa State, Nigeria: geographic information system approach.

    Science.gov (United States)

    Mayomi, Ikusemoran; Elisha, Ibrahim

    2011-12-01

    It is observed that most of the commercial boreholes in Mubi Metropolis are located along River Yedzeram which is the main river that runs across the town. Unfortunately, due to the geographical location of the town in savanna region with minimal water supply, water related small scale industries such as sachet water, block making, irrigation agriculture, cloth dying, car wash and other pollution activities such as mechanical workshops and public toilets are also located along the same River Yedzeram. Moreover, the inhabitants of the town either dump their refuse in the River or spread it on their farmlands as there is no provision of refuse dump site by the government. Therefore, five parameters (Nitrate, Magnesium, Copper, Calcium and Iron) were used to test thewater quality of water samples that were collected from twenty two commercial boreholes along the river, using the standard examination of water and waste water of the World Health Organization to determine the water quality of the boreholes. The study revealed that only eight out of the twenty two boreholes are of good quality, while the others are either of bad quality or not portable. ArcGIS 9.2 and ILWIS 3.3 software were used to analyze the laboratory results through the use of SQL queries. It was recommended that the government should provide portable water, establish water quality control board and make use of GIS for creation of database and analysis.

  8. A non-commercial approach for the generation of transgenic Leishmania tarentolae and its application in antileishmanial drug discovery.

    Science.gov (United States)

    Pineda, Tatiana; Valencia, Yesenia; Flórez, María F; Pulido, Sergio A; Vélez, Iván D; Robledo, Sara M

    2016-08-01

    Leishmaniasis is a parasitic infection caused by several species of the genus Leishmania that is considered as a neglected disease. Drug development process requires a robust and updated high-throughput technology to the evaluation of candidate compounds that imply the manipulation of the pathogenic species of the parasite in the laboratory. Therefore, it is restricted to trained personal and level II biosafety environments. However, it has been established the utility of Leishmania tarentolae as a model for in vitro screening of antileishmanial agents without the necessity of level II biosafety setups. In parallel the transfection of Leishmania parasites with reporter genes as the eGFP using non-commercial integration vectors like the pIRmcs3(-) has proved to be a powerful tool for the implementation of semi automatized high-throughput platforms for the evaluation of antileishmanial compounds. Here we report the generation of a new L. tarentolae strain overexpressing the eGFP gene harboured by the non-commercial vector pIR3(-). We also demonstrate its utility for the semi-automatized screening of antileshmanial compounds in intracellular forms of the L. tarentolae parasite.

  9. Risk Factors for Disseminated Coccidioidomycosis, United States.

    Science.gov (United States)

    Odio, Camila D; Marciano, Beatriz E; Galgiani, John N; Holland, Steven M

    2017-02-01

    Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.

  10. An ethnomethodological approach to examine exploitation in the context of capacity, trust and experience of commercial surrogacy in India.

    Science.gov (United States)

    Saravanan, Sheela

    2013-08-20

    The socio-ethical concerns regarding exploitation in commercial surrogacy are premised on asymmetric vulnerability and the commercialization of women's reproductive capacity to suit individualistic motives. In examining the exploitation argument, this article reviews the social contract theory that describes an individual as an 'economic man' with moral and/or political motivations to satisfy individual desires. This study considers the critique by feminists, who argue that patriarchal and medical control prevails in the surrogacy contracts. It also explores the exploitative dynamics amongst actors in the light of Baier's conceptualization of trust and human relationship, within which both justice and exploitation thrive, and Foucault's concept of bio-power. Drawing on these concepts, this paper aims to investigate the manifestations of exploitation in commercial surrogacy in the context of trust, power and experiences of actors, using a case study of one clinic in India. The actors' experiences are evaluated at different stages of the surrogacy process: recruitment, medical procedures, living in the surrogate home, bonding with the child and amongst actors, financial dealings, relinquishment and post-relinquishment.This study applies ethnomethodology to identify phenomena as perceived by the actors in a situation, giving importance to their interpretations of the rules that make collective activity possible. The methods include semi-structured interviews, discussions, participant observation and explanation of the phenomena from the actors' perspectives. Between August 2009 and April 2010, 13 surrogate mothers (SMs), 4 intended parents (IPs) and 2 medical practitioners (MPs) from one clinic in Western India were interviewed.This study reveals that asymmetries of capacity amongst the MPs, SMs, IPs and surrogate agents (SAs) lead to a network of trust and designation of powers through rules, bringing out the relevance of Baier's conceptualization of asymmetric

  11. A systematic approach for the chromatographic fractionation and purification of major steroid saponins in commercial extracts of Yucca schidigera Roezl.

    Science.gov (United States)

    Sastre, F; Ferreira, F; Pedreschi, F

    2017-03-01

    Yucca schidigera Roezl. (yucca) is one of the major industrial sources of steroid saponins used as animal and human food additives. This work describes a new, systematic and reproducible three-step method by medium and high-pressure liquid chromatography (under RP, NP and RP conditions), for the isolation and purification of three groups of saponins, which were further purified in six sub-fractions, and finally into twelve individual steroid saponins previously reported in Y. schidigera. In accordance to the increasing applications of yucca extracts, further analytical, biological and physicochemical studies are still required. The presented method is applicable to the preparation of steroids saponins previously reported in commercial extracts of Y. schidigera, both as highly purified mixtures of defined composition, including twelve pure components. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Effective Dissemination - Building an 'Evidence to Impact' Strategy

    Directory of Open Access Journals (Sweden)

    Dan O'Neill

    2017-02-01

    Full Text Available When a piece of ‘evidence’ is generated in the research environment and almost nobody hears about it, then can we really still call it a piece of ‘evidence’? Does evidence only become evidence once it is used; and until then, is it just a piece of insignificant information? As we inexorably travel through the EBVM era, we must increasingly prioritise effective dissemination of evidence. This paper will use the VetCompass Programme at the Royal Veterinary College as a case study to explore a strategic dissemination plan and examine routes for effective dissemination.Although EBVM traditionally assumes an audience of academics or practicing veterinarians, the authors contend that substantial welfare gains can be additionally achieved by targeting current and future pet owners, the non-owner general public, industry, welfare bodies, scientific groups, breeders and kennel clubs. Effective dissemination should be strategic and give a priori consideration to identifying target audiences, appropriate formatting of the messages and open access routes for dissemination. Scientists who generate EBVM may not always be best placed to also disseminate these messages and therefore research teams should consider widening their combined skill-base to also incorporate marketing and media savvy.The VetCompass Programme is a new and hugely exciting project that shares de-identified primary-practice clinical data for research to support effective evidence based veterinary medicine and welfare reforms. VetCompass data collection commenced in 2009 and the current 470 collaborating primary-care practices have shared data on 4 million small animals and 45 million unique episodes of care. VetCompass has 15 peer-reviewed publications to date.In order to maximise the welfare gains from an array of evidence silos generated within VetCompass, a dissemination strategy was designed based on a Systems Thinking approach. The outcomes from a range of dissemination trials

  13. An Approach Based on HPLC-Fingerprint and Chemometrics to Quality Consistency Evaluation of Matricaria chamomilla L. Commercial Samples

    Science.gov (United States)

    Viapiana, Agnieszka; Struck-Lewicka, Wiktoria; Konieczynski, Pawel; Wesolowski, Marek; Kaliszan, Roman

    2016-01-01

    Chamomile has been used as an herbal medication since ancient times and is still popular because it contains various bioactive phytochemicals that could provide therapeutic effects. In this study, a simple and reliable HPLC method was developed to evaluate the quality consistency of nineteen chamomile samples through establishing a chromatographic fingerprint, quantification of phenolic compounds and determination of antioxidant activity. For fingerprint analysis, 12 peaks were selected as the common peaks to evaluate the similarities of commercial samples of chamomile obtained from different manufacturers. A similarity analysis was performed to assess the similarity/dissimilarity of chamomile samples where values varied from 0.868 to 0.990 what indicating that samples from different manufacturers were consistent. Additionally, simultaneous quantification of five phenolic acids (gallic, caffeic, syringic, p-coumaric, ferulic) and four flavonoids (rutin, myricetin, quercetin and keampferol) was performed to interpret the quality consistency. In quantitative analysis, the nine individual phenolic compounds showed good regression (r > 0.9975). Inter- and intra-day precisions for all analyzed compounds expressed as relative standard deviation (CV) ranged from 0.05% to 3.12%. Since flavonoids and other polyphenols are commonly recognized as natural antioxidants, the antioxidant activity of chamomile samples was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing/antioxidant power (FRAP) assay. Correlation analysis was used to assess the relationship between antioxidant activity and phenolic composition, and multivariate analysis (PCA and HCA) were applied to distinguish chamomile samples. Results shown in the study indicate high similarity of chamomile samples among them, widely spread in the market and commonly used by people as infusions or teas, as well as that there were no statistically significant differences among

  14. An approach based on HPLC-fingerprint and chemometrics to quality consistency evaluation of Matricaria chamomilla L. commercial samples

    Directory of Open Access Journals (Sweden)

    Agnieszka Viapiana

    2016-10-01

    Full Text Available Chamomile has been used as an herbal medication since ancient times and is still popular because it contains various bioactive phytochemicals that could provide therapeutic effects. In this study, a simple and reliable HPLC method was developed to evaluate the quality consistency of nineteen chamomile samples through establishing a chromatographic fingerprint, quantification of phenolic compounds and determination of antioxidant activity. For fingerprint analysis, 12 peaks were selected as the common peaks to evaluate the similarities of commercial samples of chamomile obtained from different manufacturers. A similarity analysis was performed to assess the similarity/dissimilarity of chamomile samples where values varied from 0.868 to 0.990 what indicating that samples from different manufacturers were consistent. Additionally, simultaneous quantification of five phenolic acids (gallic, caffeic, syringic, p-coumaric, ferulic and four flavonoids (rutin, myricetin, quercetin and keampferol was performed to interpret the quality consistency. In quantitative analysis, the nine individual phenolic compounds showed good regression (r > 0.9975. Inter- and intra-day precisions for all analysed compounds expressed as relative standard deviation (CV ranged from 0.05% to 3.12%. Since flavonoids and other polyphenols are commonly recognised as natural antioxidants, the antioxidant activity of chamomile samples was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging activity and ferric reducing/antioxidant power (FRAP assay. Correlation analysis was used to assess the relationship between antioxidant activity and phenolic composition, and multivariate analysis (PCA and HCA were applied to distinguish chamomile samples. Results shown in the study indicate high similarity of chamomile samples among them, widely spread in the market and commonly used by people as infusions or teas, as well as that there were no statistically significant

  15. Transport behaviour of commercially available 100-Omega standard resistors

    CSIR Research Space (South Africa)

    Schumacher, B

    2001-04-01

    Full Text Available Several types of commercial 100-Omega resistors can be used with the cryogenic current comparator to maintain the resistance unit, derived from the Quantized Hall Effect (QHE), and to disseminate this unit to laboratory resistance standards. Up...

  16. Do-It-Yourself: A Special Library's Approach to Creating Dynamic Web Pages Using Commercial Off-The-Shelf Applications

    Science.gov (United States)

    Steeman, Gerald; Connell, Christopher

    2000-01-01

    Many librarians may feel that dynamic Web pages are out of their reach, financially and technically. Yet we are reminded in library and Web design literature that static home pages are a thing of the past. This paper describes how librarians at the Institute for Defense Analyses (IDA) library developed a database-driven, dynamic intranet site using commercial off-the-shelf applications. Administrative issues include surveying a library users group for interest and needs evaluation; outlining metadata elements; and, committing resources from managing time to populate the database and training in Microsoft FrontPage and Web-to-database design. Technical issues covered include Microsoft Access database fundamentals, lessons learned in the Web-to-database process (including setting up Database Source Names (DSNs), redesigning queries to accommodate the Web interface, and understanding Access 97 query language vs. Standard Query Language (SQL)). This paper also offers tips on editing Active Server Pages (ASP) scripting to create desired results. A how-to annotated resource list closes out the paper.

  17. Dissemination and geovisualization of territorial entities' history

    Directory of Open Access Journals (Sweden)

    Christine Plumejeaud

    2014-06-01

    Full Text Available This paper describes an innovative solution for geovisualization of the demographic and administrative history of French municipalities, named "communes" in French. This solution allows for the open dissemination of such data. The challenge is to provide a web interface for unskilled users in order to help them understand complex information about the demographic evolution of French territories. Our approach combines interactive thematic, spatial, and temporal views. We describe our architecture, based on open-source technologies, and the organization of this imperfect geo-historical information in our spatiotemporal database. Our second contribution concerns the concept of an acquaintance graph that has been used to obtain an efficient design with good performance in our geovisualization website.

  18. Game theory approach to use of non-commercial power plants under time-of-use pricing

    International Nuclear Information System (INIS)

    Maeda, A.; Kaya, Y.

    1992-01-01

    There has been much research done on pricing theories for electric power utilities study. This paper employs the game theory approach for evaluating the impact of the introduction of customer owned NCP upon the pricing process when TOUP is used. We have derived various interesting results from this analysis some of which are; the conflict between NCP customers and the supplier forces the supplier to reduce the price for NCP customers, also perception of the situation in which they are involved plays an important role in this conflict. The game model analysis presented in this paper provides us detailed quantitative information on electricity prices and on the ways of using NCP

  19. Analysis of eighty-four commercial aviation incidents - Implications for a resource management approach to crew training

    Science.gov (United States)

    Murphy, M. R.

    1980-01-01

    A resource management approach to aircrew performance is defined and utilized in structuring an analysis of 84 exemplary incidents from the NASA Aviation Safety Reporting System. The distribution of enabling and associated (evolutionary) and recovery factors between and within five analytic categories suggests that resource management training be concentrated on: (1) interpersonal communications, with air traffic control information of major concern; (2) task management, mainly setting priorities and appropriately allocating tasks under varying workload levels; and (3) planning, coordination, and decisionmaking concerned with preventing and recovering from potentially unsafe situations in certain aircraft maneuvers.

  20. An approach in the early stages of design to low-energy architecture for commercial buildings in Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Do, V.T. [Sustainable Energy Action Ltd., London (United Kingdom)]|[London South Bank Univ., London (United Kingdom)

    2006-07-01

    Vietnam is currently among the fastest growing economies in the world, with high energy demands. Energy consumption in the building sector is increasing rapidly as the demand for modern facilities and office space increases. Vietnam's construction sector is responsible for nearly 30 per cent of total carbon dioxide (CO{sub 2}) emission in the country. This paper focused on the importance of commercial buildings in the total energy consumption of Vietnam. Although Vietnamese architects are aware of environmental issues, there is a lack of readily available information and design tools to enable them to achieve low-emission and energy-efficient buildings. A simple and user-friendly calculation tool which can be used at the early stages of design would be useful in helping architects find the best design strategies and solutions for fenestration, structure, lighting and air-conditioning. This paper described the development of such a tool and presented some results of its use. It summarized the results of parametric studies investigating the effect of design variables on the total energy performance of office buildings in Vietnam using the Thermal Analysis System (TAS) computer simulation tool. It also documented the procedure used for the development of the Simplified Low-energy Architecture Design Tool (SLEADT). SLEADT was developed based on computer analysis and is capable of optimizing critical design decisions such as the distribution of glazing and the effect of orientation on energy loads. It was shown that a typical large office building located in Hochiminh City will use about 17 per cent more energy than the same building located in Hanoi, assuming the same air-conditioning system was used in each building. The glazing ratio was shown to have the largest impact on energy loads in both cities. Loads can be reduced by as much as 20 per cent by using appropriate glazing ratios. It was therefore recommended that requirements be imposed on the details of

  1. An integrated approach combining HPLC, GC/MS, NIRS, and chemometrics for the geographical discrimination and commercial categorization of saffron.

    Science.gov (United States)

    Liu, Jiangdi; Chen, Na; Yang, Jian; Yang, Bin; Ouyang, Zhen; Wu, Changxun; Yuan, Yuan; Wang, Weihao; Chen, Min

    2018-07-01

    In the present study, an integrated approach combining HPLC/DAD, GC/MS, near infrared (NIR) spectroscopy, and chemometrics was used to geographically discriminate saffron samples from Iran and China. Chinese and Iranian samples can be well-separated based on HPLC data analysed by a principal component analysis and an orthogonal partial least squares discriminant analysis. Picrocrocin and two types of crocins were found to be the discriminating variables, and the Chinese samples had higher contents of safranal and picrocrocin but lower cis-crocin 3Gg, kaempferol-3-O-sophoroside and isophorone. Furthermore, an NIR method was successfully established to rapidly distinguish the Chinese and Iranian samples. The relationship between an ISO standard and the contents of the chemical indices was also studied. The results indicated that the ISO standard should be revised, especially for analysing safranal. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. Commercial Toilets

    Science.gov (United States)

    Whether you are looking to reduce water use in a new facility or replace old, inefficient toilets in commercial restrooms, a WaterSense labeled flushometer-valve toilet is a high-performance, water-efficient option worth considering.

  3. Space Commercialization

    Science.gov (United States)

    Martin, Gary L.

    2011-01-01

    A robust and competitive commercial space sector is vital to continued progress in space. The United States is committed to encouraging and facilitating the growth of a U.S. commercial space sector that supports U.S. needs, is globally competitive, and advances U.S. leadership in the generation of new markets and innovation-driven entrepreneurship. Energize competitive domestic industries to participate in global markets and advance the development of: satellite manufacturing; satellite-based services; space launch; terrestrial applications; and increased entrepreneurship. Purchase and use commercial space capabilities and services to the maximum practical extent Actively explore the use of inventive, nontraditional arrangements for acquiring commercial space goods and services to meet United States Government requirements, including measures such as public-private partnerships, . Refrain from conducting United States Government space activities that preclude, discourage, or compete with U.S. commercial space activities. Pursue potential opportunities for transferring routine, operational space functions to the commercial space sector where beneficial and cost-effective.

  4. Focus stacking: Comparing commercial top-end set-ups with a semi-automatic low budget approach. A possible solution for mass digitization of type specimens

    Directory of Open Access Journals (Sweden)

    Jonathan Brecko

    2014-12-01

    Full Text Available In this manuscript we present a focus stacking system, composed of commercial photographic equipment. The system is inexpensive compared to high-end commercial focus stacking solutions. We tested this system and compared the results with several different software packages (CombineZP, Auto-Montage, Helicon Focus and Zerene Stacker. We tested our final stacked picture with a picture obtained from two high-end focus stacking solutions: a Leica MZ16A with DFC500 and a Leica Z6APO with DFC290. Zerene Stacker and Helicon Focus both provided satisfactory results. However, Zerene Stacker gives the user more possibilities in terms of control of the software, batch processing and retouching. The outcome of the test on high-end solutions demonstrates that our approach performs better in several ways. The resolution of the tested extended focus pictures is much higher than those from the Leica systems. The flash lighting inside the Ikea closet creates an evenly illuminated picture, without struggling with filters, diffusers, etc. The largest benefit is the price of the set-up which is approximately € 3,000, which is 8 and 10 times less than the LeicaZ6APO and LeicaMZ16A set-up respectively. Overall, this enables institutions to purchase multiple solutions or to start digitising the type collection on a large scale even with a small budget.

  5. Focus stacking: Comparing commercial top-end set-ups with a semi-automatic low budget approach. A possible solution for mass digitization of type specimens.

    Science.gov (United States)

    Brecko, Jonathan; Mathys, Aurore; Dekoninck, Wouter; Leponce, Maurice; VandenSpiegel, Didier; Semal, Patrick

    2014-01-01

    In this manuscript we present a focus stacking system, composed of commercial photographic equipment. The system is inexpensive compared to high-end commercial focus stacking solutions. We tested this system and compared the results with several different software packages (CombineZP, Auto-Montage, Helicon Focus and Zerene Stacker). We tested our final stacked picture with a picture obtained from two high-end focus stacking solutions: a Leica MZ16A with DFC500 and a Leica Z6APO with DFC290. Zerene Stacker and Helicon Focus both provided satisfactory results. However, Zerene Stacker gives the user more possibilities in terms of control of the software, batch processing and retouching. The outcome of the test on high-end solutions demonstrates that our approach performs better in several ways. The resolution of the tested extended focus pictures is much higher than those from the Leica systems. The flash lighting inside the Ikea closet creates an evenly illuminated picture, without struggling with filters, diffusers, etc. The largest benefit is the price of the set-up which is approximately € 3,000, which is 8 and 10 times less than the LeicaZ6APO and LeicaMZ16A set-up respectively. Overall, this enables institutions to purchase multiple solutions or to start digitising the type collection on a large scale even with a small budget.

  6. A model for personnel selection with a data mining approach: A case study in a commercial bank

    Directory of Open Access Journals (Sweden)

    Adel Azar

    2013-04-01

    Full Text Available Orientation: The success or failure of an organisation has a direct relationship with how its human resources are employed and retained. Research purpose: In this paper, a decision-making tool is provided for managers to use during the recruitment process. The effective factors in employees’ performance will be identified by discovering covert patterns of the relationship between employees’ test scores and their performance at work. Motivation for the study: Large amounts of information and data on entrance evaluations and processes have been kept in organisations. There is a need to discover the pattern in the relationship between employee’s test scores and their performance at work as a tool for use during the recruitment process.? Research design, approach and method: The data mining technique that was used in this project serves as the decision tree. Rules derivation was accomplished by the Quick Unbiased and Efficient Statistical Tree(QUEST, Chi-squared Automatic Interaction Detector (CHAID,C5.0 and Classification And Regression Tree  (CART algorithm. The objective and the appropriate algorithm were determined based on seemingly ‘irrelevant’ components, which the Commerce Bank Human Resources management’s experts describe. Main finding: It was found that the ‘performance assessment’ variable was not considered as the objective. Also, it was concluded that out of 26 effective variables only five variables, such as province of employment, education level, exam score, interview score and work experience, had the most effect on the ‘promotion score’ target. Practical/managerial implication: The database and personnel information of the Commerce Bank of Iran (in 2005 and 2006 was studied and analysed as a case study in order to identify the labour factors that are effective in job performance. Appropriate and scientific employment of staff that were selected from the entrance exams of companies and

  7. A model for personnel selection with a data mining approach: A case study in a commercial bank

    Directory of Open Access Journals (Sweden)

    Adel Azar

    2013-01-01

    Full Text Available Orientation: The success or failure of an organisation has a direct relationship with how its human resources are employed and retained.Research purpose: In this paper, a decision-making tool is provided for managers to use during the recruitment process. The effective factors in employees’ performance will be identified by discovering covert patterns of the relationship between employees’ test scores and their performance at work.Motivation for the study: Large amounts of information and data on entrance evaluations and processes have been kept in organisations. There is a need to discover the pattern in the relationship between employee’s test scores and their performance at work as a tool for use during the recruitment process.?Research design, approach and method: The data mining technique that was used in this project serves as the decision tree. Rules derivation was accomplished by the Quick Unbiased and Efficient Statistical Tree(QUEST, Chi-squared Automatic Interaction Detector (CHAID,C5.0 and Classification And Regression Tree  (CART algorithm. The objective and the appropriate algorithm were determined based on seemingly ‘irrelevant’ components, which the Commerce Bank Human Resources management’s experts describe.Main finding: It was found that the ‘performance assessment’ variable was not considered as the objective. Also, it was concluded that out of 26 effective variables only five variables, such as province of employment, education level, exam score, interview score and work experience, had the most effect on the ‘promotion score’ target.Practical/managerial implication: The database and personnel information of the Commerce Bank of Iran (in 2005 and 2006 was studied and analysed as a case study in order to identify the labour factors that are effective in job performance. Appropriate and scientific employment of staff that were selected from the entrance exams of companies and organisations

  8. Sensitive Information Gathering and Dissemination: An Assessment ...

    African Journals Online (AJOL)

    Yet the freedom of expression granted to all men is not absolute. This paper on sensitive information gathering and dissemination focuses on the role of the military and that of the media in the gathering and dissemination of information often termed sensitive, contentious and inciting. It is based on past and present media ...

  9. Federal Mechanisms to Support Intervention Dissemination

    Science.gov (United States)

    Diana, Augusto; Bennett, Nicole

    2015-01-01

    This paper examines federal mechanisms that support program developers and researchers in disseminating effective interventions for public benefit. The purpose of this paper is not to discuss the dissemination of intervention research (i.e., how to inform stakeholders about research findings), nor is it intended to discuss the research of…

  10. A Rare Sequela of Acute Disseminated Encephalomyelitis

    OpenAIRE

    Vijay Kodadhala; Saravana Devulapalli; Mohankumar Kurukumbi; Annapurni Jayam-Trouth

    2014-01-01

    Acute disseminated encephalomyelitis is a demyelinating disease, typically occurring in children following a febrile infection or a vaccination. Primary and secondary immune responses contribute to inflammation and subsequent demyelination, but the exact pathogenesis is still unknown. Diagnosis of acute disseminated encephalomyelitis is strongly suggested by temporal relationship between an infection or an immunization and the onset of neurological symptoms. Biopsy is definitive. In general, ...

  11. Converting hard copy documents for electronic dissemination

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, F.

    1994-12-31

    Since the advent of computer systems, the goal of a paperless office, and even a paperless society, has been pursued. While the normal paper flow in an organization is far from totally automated, particularly for items requiring signatures or authorizations, electronic information dissemination is becoming an almost simple task. The reasons for providing on-line documents are many and include faster and easier access for everyone, elimination of printing costs, reduction of wasted shelf and desk space, and the security of having a centrally-located, always up-to-date document. New computer software even provides the user with the ability to annotate documents and to have bookmarks so that the old scribbled-in and dog-eared manual can be replaced without loosing this `customizability`. Moreover, new hypermedia capabilities mean that documents can be read in a non-linear fashion and can include color figures and photographs, audio, and even animation sequences, capabilities which exceed those of paper. The proliferation of network-based information servers, coupled with the growth of the Internet, has enticed academic, governmental, and even commercial organizations to provide increasing numbers of documents and data bases in electronic form via the network, not just to internal staff, but to the public as well. Much of this information, which includes everything from mundane company procedures to spiffy marketing brochures, was previously published only in hard copy. Converting existing documents to electronic form and producing only electronic versions of new documents poses some interesting challenges to the maintainer or author.

  12. Commercial imagery archive product development

    Science.gov (United States)

    Sakkas, Alysa

    1999-12-01

    The Lockheed Martin (LM) team had garnered over a decade of operational experience in digital imagery management and analysis for the US Government at numerous worldwide sites. Recently, it set out to create a new commercial product to serve the needs of large-scale imagery archiving and analysis markets worldwide. LM decided to provide a turnkey commercial solution to receive, store, retrieve, process, analyze and disseminate in 'push' or 'pull' modes components and adapted and developed its own algorithms to provide added functionality not commercially available elsewhere. The resultant product, Intelligent Library System, satisfies requirements for (a) a potentially unbounded, data archive automated workflow management for increased user productivity; (c) automatic tracking and management of files stored on shelves; (d) ability to ingest, process and disseminate data involves with bandwidths ranging up to multi-gigabit per second; (e) access through a thin client- to-server network environment; (f) multiple interactive users needing retrieval of filters in seconds from both archived images or in real time, and (g) scalability that maintains information throughput performance as the size of the digital library grows.

  13. Wireless Emergency Alerts Commercial Mobile Service Provider (CMSP) Cybersecurity Guidelines

    Science.gov (United States)

    2016-06-16

    Wireless Emergency Alerts Commercial Mobile Service Provider (CMSP) Cybersecurity Guidelines Christopher Alberts Audrey Dorofee Carol Woody...Technology Direc- torate. The WEA capability provides a valuable service , disseminating emergency alerts to users of capable mobile devices if they are... mobile service providers (CMSPs)—commercial wireless carriers that broadcast WEA messages to a designated geographic area 4. Alert recipients—the

  14. A Community-Based Participatory Research Guided Model for the Dissemination of Evidence-Based Interventions.

    Science.gov (United States)

    Delafield, Rebecca; Hermosura, Andrea Nacapoy; Ing, Claire Townsend; Hughes, Claire K; Palakiko, Donna-Marie; Dillard, Adrienne; Kekauoha, B Puni; Yoshimura, Sheryl R; Gamiao, Shari; Kaholokula, Joseph Keawe

    Dissemination is a principle within community-based participatory research (CBPR); however, published research focuses on the dissemination of findings from CBPR projects but less on dissemination of interventions developed through CBPR approaches. To disseminate an evidence-based lifestyle intervention tailored for Native Hawaiians and other Pacific Islanders, the PILI 'Ohana Project (POP), an 11-year CBPR initiative, developed an innovative dissemination model. The community-to-community mentoring (CCM) model described in this paper extends the application of CBPR values and principles used in intervention development to intervention dissemination. The CCM model combines a CBPR orientation with the diffusion of innovation theory, the social cognitive theory, and key concepts from community organizing and community building to address the multilevel factors that influence uptake of an evidence-based intervention (EBI). Grounding the model in CBPR principles provides benefits for intervention dissemination and integrates a focus on community benefits and capacity building. By establishing co-equal, mutually beneficial relationships at the core of the CCM model, opportunities are created for building critical consciousness, community capacity, and social capital. More research is needed to determine the effectiveness of this model of intervention dissemination which may enhance diffusion of CBPR interventions and empower communities in the process.

  15. Disposition Kinetics of Taxanes in Peritoneal Dissemination

    Directory of Open Access Journals (Sweden)

    Ken'ichi Miyamoto

    2012-01-01

    Full Text Available Treatment of cancers in the abdominal cavity, such as peritoneal dissemination, is difficult, but in principle intraperitoneal administration of anticancer drugs is expected to be preferable to systemic administration. Taxane anticancer drugs are used to treat gastric cancer patients with peritoneal dissemination. They are administered as micellar preparations, Taxol and Taxotere, which consist of paclitaxel in Cremophor EL (crEL and docetaxel in Polysorbate-80 (PS-80, respectively. In this paper we review the disposition kinetics of taxane anticancer drugs after intraperitoneal administration in peritoneal dissemination patients and animal models and also discuss the effect of the surfactant vehicle on the behavior of taxanes.

  16. Disseminated histoplasmosis in an 'immunocompetent' child ...

    African Journals Online (AJOL)

    A rare case of severe disseminated histoplasmosis in a 7-year-old boy with apparently normal immune function is described. Current recommendations for diagnostic investigations, monitoring and the treatment of this disease with amphotericin B and itraconazole are reviewed.

  17. Multiagent Based Information Dissemination in Vehicular Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    S.S. Manvi

    2009-01-01

    Full Text Available Vehicular Ad hoc Networks (VANETs are a compelling application of ad hoc networks, because of the potential to access specific context information (e.g. traffic conditions, service updates, route planning and deliver multimedia services (Voice over IP, in-car entertainment, instant messaging, etc.. This paper proposes an agent based information dissemination model for VANETs. A two-tier agent architecture is employed comprising of the following: 1 'lightweight', network-facing, mobile agents; 2 'heavyweight', application-facing, norm-aware agents. The limitations of VANETs lead us to consider a hybrid wireless network architecture that includes Wireless LAN/Cellular and ad hoc networking for analyzing the proposed model. The proposed model provides flexibility, adaptability and maintainability for traffic information dissemination in VANETs as well as supports robust and agile network management. The proposed model has been simulated in various network scenarios to evaluate the effectiveness of the approach.

  18. Quality evaluation of Terpinen-4-ol type Australian Tea Tree oils and commercial products: An integrated approach using conventional and chiral GC/MS combined with chemometrics

    Science.gov (United States)

    Conventional GC/MS, chiral GC/MS and chemometric techniques were used to evaluate a large set of tea tree oils (TTO) and commercial products purported to contain tea tree oils. Fifty-seven known provenance pure Australian tea tree oils and forty-seven commercial TTO products were investigated. Twent...

  19. Commercial LANDSAT?

    Science.gov (United States)

    Private industry should assume responsibility either for the United States' land satellite (LANDSAT) system or for both the land and the weather satellite systems, recommends the Land Remote Sensing Satellite Advisory Committee. The committee (Eos, June 29, 1982, p. 553), composed of representatives from academia, industry, and government, has a working group that is evaluating the potential for commercialization of remote sensing satellites.The recommendations call for industry ownership or operation of either or both of the remote sensing systems, but only up to and including the holding of raw, unprocessed data. The National Aeronautics and Space Administration (NASA) currently operates LANDSAT but will be relinquishing its responsibility to the National Oceanic and Atmospheric Administration (NOAA) on January 31. NOAA already operates the U.S. civilian weather satellite service, which includes the NOAA-5, NOAA-6, and the Geostationary Operational Environmental (GOES) satellites (Eos, June 2, 1981, p. 522).

  20. Dissemination and use of a participatory ergonomics guide for workplaces.

    Science.gov (United States)

    Van Eerd, Dwayne; King, Trevor; Keown, Kiera; Slack, Tesha; Cole, Donald C; Irvin, Emma; Amick, Benjamin C; Bigelow, Philip

    2016-06-01

    Musculoskeletal disorders (MSDs) result in lost-time injury claims and lost productivity worldwide, placing a substantial burden on workers and workplaces. Participatory ergonomics (PE) is a popular approach to reducing MSDs; however, there are challenges to implementing PE programmes. Using evidence to overcome challenges may be helpful but the impacts of doing so are unknown. We sought to disseminate an evidence-based PE tool and to describe its use. An easy-to-use, evidence-based PE Guide was disseminated to workplace parties, who were surveyed about using the tool. The greatest barrier to using the tool was a lack of time. Reported tool use included for training purposes, sharing and integrating the tool into existing programmes. New actions related to tool use included training, defining team responsibilities and suggesting programme implementation steps. Evidence-based tools could help ergonomists overcome some challenges involved in implementing injury reduction programmes such as PE. Practitioner Summary Practitioners experience challenges implementing programmes to reduce the burden of MSDs in workplaces. Implementing participatory interventions requires multiple workplace parties to be 'on-board'. Disseminating and using evidence-based guides may help to overcome these challenges. Using evidence-based tools may help ergonomics practitioners implement PE programmes.

  1. A Rare Sequela of Acute Disseminated Encephalomyelitis

    Directory of Open Access Journals (Sweden)

    Vijay Kodadhala

    2014-01-01

    Full Text Available Acute disseminated encephalomyelitis is a demyelinating disease, typically occurring in children following a febrile infection or a vaccination. Primary and secondary immune responses contribute to inflammation and subsequent demyelination, but the exact pathogenesis is still unknown. Diagnosis of acute disseminated encephalomyelitis is strongly suggested by temporal relationship between an infection or an immunization and the onset of neurological symptoms. Biopsy is definitive. In general, the disease is self-limiting and the prognostic outcome is favorable with anti-inflammatory and immunosuppressive agents. Locked-in syndrome describes patients who are awake and conscious but have no means of producing limb, speech, or facial movements. Locked-in syndrome is a rare complication of acute disseminated encephalomyelitis. We present a case of incomplete locked-in syndrome occurring in a 34-year-old male secondary to acute disseminated encephalomyelitis. Our case is unique, as acute disseminated encephalomyelitis occurred in a 34-year-old which was poorly responsive to immunosuppression resulting in severe disability.

  2. Smart-tag Based Data Dissemination

    DEFF Research Database (Denmark)

    Bonnet, Philippe; Beaufour, Allan; Leopold, Martin

    2002-01-01

    Monitoring wide, hostile areas requires disseminating data between fixed, disconnected clusters of sensor nodes. It is not always possible to install long-range radios in order to cover the whole area. We propose to leverage the movement of mobile individuals, equipped with smart-tags, to dissemi......-tag based data dissemination. We use simulation to study the characteristics of the model we propose. Finally, we present an implementation based on Bluetooth smart-tags.......Monitoring wide, hostile areas requires disseminating data between fixed, disconnected clusters of sensor nodes. It is not always possible to install long-range radios in order to cover the whole area. We propose to leverage the movement of mobile individuals, equipped with smart......-tags, to disseminate data across disconnected static nodes spread across a wide area. Static nodes and mobile smart-tags exchange data when they are in the vicinity of each other; smart-tags disseminate data as they move around. In this paper, we propose an algorithm for update propagation and a model for smart...

  3. Comprehensive analysis of information dissemination in disasters

    Science.gov (United States)

    Zhang, N.; Huang, H.; Su, Boni

    2016-11-01

    China is a country that experiences a large number of disasters. The number of deaths caused by large-scale disasters and accidents in past 10 years is around 900,000. More than 92.8 percent of these deaths could be avoided if there were an effective pre-warning system deployed. Knowledge of the information dissemination characteristics of different information media taking into consideration governmental assistance (information published by a government) in disasters in urban areas, plays a critical role in increasing response time and reducing the number of deaths and economic losses. In this paper we have developed a comprehensive information dissemination model to optimize efficiency of pre-warning mechanics. This model also can be used for disseminating information for evacuees making real-time evacuation plans. We analyzed every single information dissemination models for pre-warning in disasters by considering 14 media: short message service (SMS), phone, television, radio, news portals, Wechat, microblogs, email, newspapers, loudspeaker vehicles, loudspeakers, oral communication, and passive information acquisition via visual and auditory senses. Since governmental assistance is very useful in a disaster, we calculated the sensitivity of governmental assistance ratio. The results provide useful references for information dissemination during disasters in urban areas.

  4. A rare sequela of acute disseminated encephalomyelitis.

    Science.gov (United States)

    Kodadhala, Vijay; Devulapalli, Saravana; Kurukumbi, Mohankumar; Jayam-Trouth, Annapurni

    2014-01-01

    Acute disseminated encephalomyelitis is a demyelinating disease, typically occurring in children following a febrile infection or a vaccination. Primary and secondary immune responses contribute to inflammation and subsequent demyelination, but the exact pathogenesis is still unknown. Diagnosis of acute disseminated encephalomyelitis is strongly suggested by temporal relationship between an infection or an immunization and the onset of neurological symptoms. Biopsy is definitive. In general, the disease is self-limiting and the prognostic outcome is favorable with anti-inflammatory and immunosuppressive agents. Locked-in syndrome describes patients who are awake and conscious but have no means of producing limb, speech, or facial movements. Locked-in syndrome is a rare complication of acute disseminated encephalomyelitis. We present a case of incomplete locked-in syndrome occurring in a 34-year-old male secondary to acute disseminated encephalomyelitis. Our case is unique, as acute disseminated encephalomyelitis occurred in a 34-year-old which was poorly responsive to immunosuppression resulting in severe disability.

  5. Agricultural information dissemination using ICTs: A review and analysis of information dissemination models in China

    Directory of Open Access Journals (Sweden)

    Yun Zhang

    2016-03-01

    Full Text Available Over the last three decades, China’s agriculture sector has been transformed from the traditional to modern practice through the effective deployment of Information and Communication Technologies (ICTs. Information processing and dissemination have played a critical role in this transformation process. Many studies in relation to agriculture information services have been conducted in China, but few of them have attempted to provide a comprehensive review and analysis of different information dissemination models and their applications. This paper aims to review and identify the ICT based information dissemination models in China and to share the knowledge and experience in applying emerging ICTs in disseminating agriculture information to farmers and farm communities to improve productivity and economic, social and environmental sustainability. The paper reviews and analyzes the development stages of China’s agricultural information dissemination systems and different mechanisms for agricultural information service development and operations. Seven ICT-based information dissemination models are identified and discussed. Success cases are presented. The findings provide a useful direction for researchers and practitioners in developing future ICT based information dissemination systems. It is hoped that this paper will also help other developing countries to learn from China’s experience and best practice in their endeavor of applying emerging ICTs in agriculture information dissemination and knowledge transfer.

  6. Commercialization of sustainable energy technologies

    International Nuclear Information System (INIS)

    Balachandra, P.; Kristle Nathan, Hippu Salk; Reddy, B. Sudhakara

    2010-01-01

    Commercialization efforts to diffuse sustainable energy technologies (SETs) have so far remained as the biggest challenge in the field of renewable energy and energy efficiency. Limited success of diffusion through government driven pathways urges the need for market based approaches. This paper reviews the existing state of commercialization of SETs in the backdrop of the basic theory of technology diffusion. The different SETs in India are positioned in the technology diffusion map to reflect their slow state of commercialization. The dynamics of SET market is analysed to identify the issues, barriers and stakeholders in the process of SET commercialization. By upgrading the 'potential adopters' to 'techno-entrepreneurs', the study presents the mechanisms for adopting a private sector driven 'business model' approach for successful diffusion of SETs. This is expected to integrate the processes of market transformation and entrepreneurship development with innovative regulatory, marketing, financing, incentive and delivery mechanisms leading to SET commercialization. (author)

  7. Commercial applications

    Science.gov (United States)

    The near term (one to five year) needs of domestic and foreign commercial suppliers of radiochemicals and radiopharmaceuticals for electromagnetically separated stable isotopes are assessed. Only isotopes purchased to make products for sale and profit are considered. Radiopharmaceuticals produced from enriched stable isotopes supplied by the Calutron facility at ORNL are used in about 600,000 medical procedures each year in the United States. A temporary or permanent disruption of the supply of stable isotopes to the domestic radiopharmaceutical industry could curtail, if not eliminate, the use of such diagnostic procedures as the thallium heart scan, the gallium cancer scan, the gallium abscess scan, and the low radiation dose thyroid scan. An alternative source of enriched stable isotopes exist in the USSR. Alternative starting materials could, in theory, eventually be developed for both the thallium and gallium scans. The development of a new technology for these purposes, however, would take at least five years and would be expensive. Hence, any disruption of the supply of enriched isotopes from ORNL and the resulting unavailability of critical nuclear medicine procedures would have a dramatic negative effect on the level of health care in the United States.

  8. Primary disseminated extrapulmonary multidrug resistant tuberculosis

    Directory of Open Access Journals (Sweden)

    S K Das

    2012-01-01

    Full Text Available Disseminated tuberculosis is a common mode of presentation of tuberculosis in patients both with and without HIV/AIDS in India. However, primary multidrug resistance in disseminated tuberculosis involving only the extrapulmonary sites in an immunocompetent adult is rare. Here, we report a case of a 19-year-old man who had disseminated tuberculosis involving left pleura, pericardium, peritoneum and intraabdominal lymph nodes. He was initially taking WHO category I antituberculous drugs, but was not responding in spite of 5 months of chemotherapy. Culture of the pleural biopsy specimen grew Mycobacterium tuberculosis which was resistant to isoniazid and rifampicin. He was put on therapy for multidrug resistant tuberculosis,following 24 months of chemotherapyhe had an uneventful recovery.

  9. Tracking Users for a Targeted Dissemination

    Directory of Open Access Journals (Sweden)

    Philippe Bautier

    2015-12-01

    Full Text Available How to build a dissemination and communication strategy in a world where users have easy access to a deluge of data and information from various origins and where IT tools and design standards change so quickly that users behaviour and their expectations are continuously modified? The first challenge of Eurostat is clearly to know what users want: we know our different types of users but we have to identify how they get our data, what they do with our data, how they react to our outputs and which sort of new service they would like us to propose. Translating these needs into a visual dissemination is a new challenge undertaken by Eurostat through a new portal, new mobile apps and new info graphs and basic application as well as increasing the visibility on Google. The objective of this paper is to share Eurostat's experience in identifying user Leeds and to show how concretely this information has been visually disseminated.

  10. Dissemination of a highly virulent pathogen: tracking the early events that define infection.

    Science.gov (United States)

    Gonzalez, Rodrigo J; Lane, M Chelsea; Wagner, Nikki J; Weening, Eric H; Miller, Virginia L

    2015-01-01

    The series of events that occurs immediately after pathogen entrance into the body is largely speculative. Key aspects of these events are pathogen dissemination and pathogen interactions with the immune response as the invader moves into deeper tissues. We sought to define major events that occur early during infection of a highly virulent pathogen. To this end, we tracked early dissemination of Yersinia pestis, a highly pathogenic bacterium that causes bubonic plague in mammals. Specifically, we addressed two fundamental questions: (1) do the bacteria encounter barriers in disseminating to draining lymph nodes (LN), and (2) what mechanism does this nonmotile bacterium use to reach the LN compartment, as the prevailing model predicts trafficking in association with host cells. Infection was followed through microscopy imaging in addition to assessing bacterial population dynamics during dissemination from the skin. We found and characterized an unexpected bottleneck that severely restricts bacterial dissemination to LNs. The bacteria that do not pass through this bottleneck are confined to the skin, where large numbers of neutrophils arrive and efficiently control bacterial proliferation. Notably, bottleneck formation is route dependent, as it is abrogated after subcutaneous inoculation. Using a combination of approaches, including microscopy imaging, we tested the prevailing model of bacterial dissemination from the skin into LNs and found no evidence of involvement of migrating phagocytes in dissemination. Thus, early stages of infection are defined by a bottleneck that restricts bacterial dissemination and by neutrophil-dependent control of bacterial proliferation in the skin. Furthermore, and as opposed to current models, our data indicate an intracellular stage is not required by Y. pestis to disseminate from the skin to draining LNs. Because our findings address events that occur during early encounters of pathogen with the immune response, this work can

  11. Dissemination of a highly virulent pathogen: tracking the early events that define infection.

    Directory of Open Access Journals (Sweden)

    Rodrigo J Gonzalez

    2015-01-01

    Full Text Available The series of events that occurs immediately after pathogen entrance into the body is largely speculative. Key aspects of these events are pathogen dissemination and pathogen interactions with the immune response as the invader moves into deeper tissues. We sought to define major events that occur early during infection of a highly virulent pathogen. To this end, we tracked early dissemination of Yersinia pestis, a highly pathogenic bacterium that causes bubonic plague in mammals. Specifically, we addressed two fundamental questions: (1 do the bacteria encounter barriers in disseminating to draining lymph nodes (LN, and (2 what mechanism does this nonmotile bacterium use to reach the LN compartment, as the prevailing model predicts trafficking in association with host cells. Infection was followed through microscopy imaging in addition to assessing bacterial population dynamics during dissemination from the skin. We found and characterized an unexpected bottleneck that severely restricts bacterial dissemination to LNs. The bacteria that do not pass through this bottleneck are confined to the skin, where large numbers of neutrophils arrive and efficiently control bacterial proliferation. Notably, bottleneck formation is route dependent, as it is abrogated after subcutaneous inoculation. Using a combination of approaches, including microscopy imaging, we tested the prevailing model of bacterial dissemination from the skin into LNs and found no evidence of involvement of migrating phagocytes in dissemination. Thus, early stages of infection are defined by a bottleneck that restricts bacterial dissemination and by neutrophil-dependent control of bacterial proliferation in the skin. Furthermore, and as opposed to current models, our data indicate an intracellular stage is not required by Y. pestis to disseminate from the skin to draining LNs. Because our findings address events that occur during early encounters of pathogen with the immune response

  12. Disseminated cysticercosis with huge muscle hypertrophy

    Directory of Open Access Journals (Sweden)

    Bandyopadhyay Debabrata

    2009-01-01

    Full Text Available Cysticercosis is caused by cysticercus cellulose, which is the larva of Taenia solium , the pork tapeworm. The larvae are carried in the blood stream after penetrating the walls of the alimentary tract and they lodge in different tissues like the skin, skeletal muscles, brain, fundus and heart, to cause disseminated cysticercosis. Cases of disseminated cysticercosis have rarely been reported in the literature. They may inhabit the muscles and cause muscular hypertrophy, which, at times, may assume gross proportions. Morbidity is usually caused by the involvement of the central nervous system or the eyes.

  13. Disseminated cutaneous sporotrichosis in patient with alcoholism

    Directory of Open Access Journals (Sweden)

    Ana Maria Benvegnú

    Full Text Available Abstract Sporotrichosis is the most prevalent subcutaneous mycosis and is characterized by a subacute or chronic development of a cutaneous or subcutaneous nodular lesion. It is caused by the dimorphic fungus Sporothrix spp, which may manifest in different clinical forms. The disseminated cutaneous form is uncommon and is more likely to occur in immunocompromised patients. We report a 47-year-old male patient with multiple cutaneous and subcutaneous nodules. The patient was diagnosed with disseminated cutaneous sporotrichosis based on the isolation and identification of Sporothrix spp. The patient was treated with potassium iodide, which resulted in clinical improvement of the lesions.

  14. Opportunities and Constraints in Disseminating Qualitative Research in Web 2.0 Virtual Environments.

    Science.gov (United States)

    Hays, Charles A; Spiers, Judith A; Paterson, Barbara

    2015-11-01

    The Web 2.0 digital environment is revolutionizing how users communicate and relate to each other, and how information is shared, created, and recreated within user communities. The social media technologies in the Web 2.0 digital ecosystem are fundamentally changing the opportunities and dangers in disseminating qualitative health research. The social changes influenced by digital innovations shift dissemination from passive consumption to user-centered, apomediated cooperative approaches, the features of which are underutilized by many qualitative researchers. We identify opportunities new digital media presents for knowledge dissemination activities including access to wider audiences with few gatekeeper constraints, new perspectives, and symbiotic relationships between researchers and users. We also address some of the challenges in embracing these technologies including lack of control, potential for unethical co-optation of work, and cyberbullying. Finally, we offer solutions to enhance research dissemination in sustainable, ethical, and effective strategies. © The Author(s) 2015.

  15. Self-disseminating vaccines for emerging infectious diseases.

    Science.gov (United States)

    Murphy, Aisling A; Redwood, Alec J; Jarvis, Michael A

    2016-01-01

    Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate of emerging infectious diseases from animals. The spate of recent infectious disease outbreaks, including Ebola virus disease and Middle East respiratory syndrome, emphasize the need for development of new innovative tools to manage these emerging diseases. Disseminating vaccines are one such novel approach to potentially interrupt animal to human (zoonotic) transmission of these pathogens.

  16. Constructing a model of effective information dissemination in a crisis. Information dissemination, Crisis, Crises, Tuberculosis, Dissemination of information, Meta-ethnographic analysis, Social marketing

    Directory of Open Access Journals (Sweden)

    Fiona Duggan

    2004-01-01

    Full Text Available A model of effective information dissemination in a crisis was developed from a Ph.D. study of information dissemination during a suspected TB outbreak. The research aimed to characterise and evaluate the dissemination of information to the community during the incident. A qualitative systematic review of the research literature identified twenty relevant studies. Meta-ethnographic analysis of these studies highlighted the key factors in effective dissemination. Consideration of these factors in relation to dissemination theory provided the links between the key factors. When the resulting model was applied to the specific circumstances of the incident two barriers to effective information dissemination were identified. Incorporating these barriers into the original model enabled the construction of a model of effective information dissemination in a crisis. The implications of this model for information professionals include incorporating social marketing as a core element of education and training and adopting multi-method dissemination strategies.

  17. Applying GRADE-CERQual to qualitative evidence synthesis findings-paper 7: understanding the potential impacts of dissemination bias.

    Science.gov (United States)

    Booth, Andrew; Lewin, Simon; Glenton, Claire; Munthe-Kaas, Heather; Toews, Ingrid; Noyes, Jane; Rashidian, Arash; Berg, Rigmor C; Nyakang'o, Brenda; Meerpohl, Joerg J

    2018-01-25

    The GRADE-CERQual (Confidence in Evidence from Reviews of Qualitative research) approach has been developed by the GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group. The approach has been developed to support the use of findings from qualitative evidence syntheses in decision-making, including guideline development and policy formulation. CERQual includes four components for assessing how much confidence to place in findings from reviews of qualitative research (also referred to as qualitative evidence syntheses): (1) methodological limitations, (2) coherence, (3) adequacy of data and (4) relevance. This paper is part of a series providing guidance on how to apply CERQual and focuses on a probable fifth component, dissemination bias. Given its exploratory nature, we are not yet able to provide guidance on applying this potential component of the CERQual approach. Instead, we focus on how dissemination bias might be conceptualised in the context of qualitative research and the potential impact dissemination bias might have on an overall assessment of confidence in a review finding. We also set out a proposed research agenda in this area. We developed this paper by gathering feedback from relevant research communities, searching MEDLINE and Web of Science to identify and characterise the existing literature discussing or assessing dissemination bias in qualitative research and its wider implications, developing consensus through project group meetings, and conducting an online survey of the extent, awareness and perceptions of dissemination bias in qualitative research. We have defined dissemination bias in qualitative research as a systematic distortion of the phenomenon of interest due to selective dissemination of studies or individual study findings. Dissemination bias is important for qualitative evidence syntheses as the selective dissemination of qualitative studies and/or study findings may distort our understanding of

  18. Disseminating research findings: what should researchers do? A systematic scoping review of conceptual frameworks

    Directory of Open Access Journals (Sweden)

    Calnan Mike W

    2010-11-01

    Full Text Available Abstract Background Addressing deficiencies in the dissemination and transfer of research-based knowledge into routine clinical practice is high on the policy agenda both in the UK and internationally. However, there is lack of clarity between funding agencies as to what represents dissemination. Moreover, the expectations and guidance provided to researchers vary from one agency to another. Against this background, we performed a systematic scoping to identify and describe any conceptual/organising frameworks that could be used by researchers to guide their dissemination activity. Methods We searched twelve electronic databases (including MEDLINE, EMBASE, CINAHL, and PsycINFO, the reference lists of included studies and of individual funding agency websites to identify potential studies for inclusion. To be included, papers had to present an explicit framework or plan either designed for use by researchers or that could be used to guide dissemination activity. Papers which mentioned dissemination (but did not provide any detail in the context of a wider knowledge translation framework, were excluded. References were screened independently by at least two reviewers; disagreements were resolved by discussion. For each included paper, the source, the date of publication, a description of the main elements of the framework, and whether there was any implicit/explicit reference to theory were extracted. A narrative synthesis was undertaken. Results Thirty-three frameworks met our inclusion criteria, 20 of which were designed to be used by researchers to guide their dissemination activities. Twenty-eight included frameworks were underpinned at least in part by one or more of three different theoretical approaches, namely persuasive communication, diffusion of innovations theory, and social marketing. Conclusions There are currently a number of theoretically-informed frameworks available to researchers that can be used to help guide their

  19. Strategies for disseminating recommendations or guidelines to patients: a systematic review.

    Science.gov (United States)

    Schipper, K; Bakker, M; De Wit, M; Ket, J C F; Abma, T A

    2016-06-07

    The aim of this systematic literature review was to assess what dissemination strategies are feasible to inform and educate patients about recommendations (also known as guidelines). The search was performed in February 2016 in PubMed, Ebsco/PsycINFO, Ebsco/CINAHL and Embase. Studies evaluating dissemination strategies, involving patients and/or reaching patients, were included. A hand search and a search in the grey literature, also done in February 2016, were added. Searches were not restricted by language or publication type. Publications that referred to (1) guideline(s) or recommendation(s), (2) dissemination, (3) dissemination with patients/patient organisations and (4) dissemination to patients/patient organisations were included in this article. Criteria 1 AND 2 were mandatory together with criteria 3 OR 4. The initial search revealed 3753 unique publications. Forty-seven articles met the inclusion criteria and were selected for detailed review. The hand search and grey literature resulted in four relevant articles. After reading the full text of the 47 articles, 21 were relevant for answering our research question. Most publications had low levels of evidence, 3 or 4 of the Oxford levels of evidence. One article had a level of evidence of 2(b). This article gives an overview of tools and strategies to disseminate recommendations to patients. Key factors of success were a dissemination plan, written at the start of the recommendation development process, involvement of patients in this development process and the use of a combination of traditional and innovative dissemination tools. The lack of strong evidence calls for more research of the effectiveness of different dissemination strategies as well as the barriers for implementing a strategic approach of dissemination. Our findings provide the first systematic overview of tools and strategies to disseminate recommendations to patients and patient organisations. Participation of patients in the whole

  20. Disseminated histoplasmosis in an 'immunocompetent' child

    African Journals Online (AJOL)

    and diffuse septic arthritis affecting the ankles, knees, elbows, wrists and the costochondral junctions. Radiographs showed evidence of severe widespread osteitis. His skin, especially on his face, showed numerous raised, umbilicated lesions. He was anaemic with mild disseminated intravascular coagulation (DIG), and ...

  1. Disseminated cutaneous histoplasmosis with laryngeal involvement ...

    African Journals Online (AJOL)

    Disseminated cutaneous histoplasmosis with laryngeal involvement in a setting of immune reconstitution inflammatory syndrome. ... Grocott-Gomori methenamine silver and Periodic acid–Schiff (PAS) stains revealed a relative paucity of intracellular, narrow-neck budding fungal organisms. Culture findings confirmed the ...

  2. documenting and disseminating agricultural indigenous knowledge ...

    African Journals Online (AJOL)

    Eric

    addition to identifying the challenges faced in its management for sustainable food security in. Uganda's district of .... also declined. The performance of crops in terms of yields also varied significantly (Plan for Modernisation of ... To propose best strategies for documenting and disseminating of AIK in Soroti district. Literature ...

  3. Adoption of improved agricultural technologies disseminated via ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-05-02

    May 2, 2008 ... The study determined farmers' adoption of improved agricultural technologies disseminated via radio ... questions and get feed back from the radio presenter and language used in presenting the programme. The study recommends ... attitude, knowledge, skills and aspiration of the receivers. In Nigeria ...

  4. A Primer on Disseminating Applied Quantitative Research

    Science.gov (United States)

    Bell, Bethany A.; DiStefano, Christine; Morgan, Grant B.

    2010-01-01

    Transparency and replication are essential features of scientific inquiry, yet scientific communications of applied quantitative research are often lacking in much-needed procedural information. In an effort to promote researchers dissemination of their quantitative studies in a cohesive, detailed, and informative manner, the authors delineate…

  5. Differential diagnosis of disseminated periventricular calcifications

    International Nuclear Information System (INIS)

    Rieger, P.; Piepgras, U.

    1986-01-01

    Juvenile disseminated periventricular calcifications may occur in tuberous sclerosis, toxoplasmosis, cytomegaly, and in tuberculous meningitis. Cysticercosis, by contrast, does not result in corresponding intracerebral foci until an older age. Differential diagnosis is no problem if clinical findings are typical (tuberous sclerosis) or if serological verification is positive. However, any unclear clinical diagnosis can often be secured by CT. (orig.) [de

  6. Thrombocytopenia and disseminated histoplasmosis in immunocompetent adults

    OpenAIRE

    Kutkut, Issa; Vater, Laura; Goldman, Mitchell; Czader, Magdalena; Swenberg, Jessica; Fulkerson, Zachary; Mehta, Rakesh

    2017-01-01

    Key Clinical Message Disseminated histoplasmosis among immunocompetent patients is rare, but may be associated with clinically significant refractory thrombocytopenia. Platelet counts often return to normal levels following antifungal therapy. Therefore, the most important management of this refractory thrombocytopenia is the recognition and treatment of histoplasmosis infection.

  7. Disseminated cutaneous histoplasmosis in newly diagnosed HIV

    OpenAIRE

    Soza, Gabriela M.; Patel, Mahir; Readinger, Allison; Ryan, Caitriona

    2016-01-01

    We present a woman with a widespread severe papulopustular eruption, fever, and fatigue of 5 weeks' duration. HIV infection was diagnosed, with an absolute CD4+ count of 3 cells/µL. The eruption was consistent with disseminated cutaneous histoplasmosis. The clinical manifestations and management of cutaneous histoplasmosis are reviewed.

  8. Fatal Disseminated Infection with Fusarium petroliphilum

    NARCIS (Netherlands)

    Ersal, Tuba; Al-Hatmi, Abdullah S M; Dalyan Cilo, Burcu; Curfs-Breuker, Ilse; Meis, Jacques F; Ozkalemkaş, Fahir; Ener, Beyza; van Diepeningen, Anne D

    2014-01-01

    Members of the Fusarium solani species complex (FSSC) are causing the majority of the fusariosis in humans. Disseminated fusariosis has a high mortality and is predominantly observed in patients with leukemia. Here, we present the case of a fatal infection by a Fusarium strain with a degenerated

  9. Factors Influencing Adoption of Cocoa Technologies Disseminated ...

    African Journals Online (AJOL)

    The study was undertaken to determine factors influencing adoption of cocoa technologies disseminated by Olam organization to cocoa farmers in Ondo State, Nigeria. Data for the study were collected from thirty cocoa farmers (Olam's model farmers) through the use of structured interview schedule. Data were analyzed ...

  10. Disseminated Intravascular Coagulation Following Induction of ...

    African Journals Online (AJOL)

    Background: Disseminated Intravascular coagulopathy (DIC) has been reported following use of Misoprostol which is an old drug with new indications in Obstetrics and. Gynecology. Its effectiveness, low cost, stability in tropical conditions and ease of administration as well as side effects like gastrointestinal effect, uterine ...

  11. Knowledge Management and Global Information Dissemination

    Science.gov (United States)

    Umunadi, Ejiwoke Kennedy

    2014-01-01

    The paper looked at knowledge management and global information dissemination. Knowledge is a very powerful tool for survival, growth and development. It can be seen as the information, understanding and skills that you gain through education or experience. The paper was addressed under the following sub-headings: Knowledge management knowledge…

  12. Differential diagnosis of disseminated periventricular calcifications

    Energy Technology Data Exchange (ETDEWEB)

    Rieger, P.; Piepgras, U.

    1986-08-01

    Juvenile disseminated periventricular calcifications may occur in tuberous sclerosis, toxoplasmosis, cytomegaly, and in tuberculous meningitis. Cysticercosis, by contrast, does not result in corresponding intracerebral foci until an older age. Differential diagnosis is no problem if clinical findings are typical (tuberous sclerosis) or if serological verification is positive. However, any unclear clinical diagnosis can often be secured by CT.

  13. The AFT Educational Research and Dissemination Program

    Science.gov (United States)

    American Federation of Teachers, 2007

    2007-01-01

    This brochure is developed to provide information for local unions within the American Federation of Teachers (AFT) who may be interested in becoming Education Research and Dissemination (ER&D) sites. The following questions are addressed: (1) What Is ER&D? (2) What Can ER&D Accomplish? (3) What Makes ER&D Different? (4) What Do ER&D Participants…

  14. Modeling and simulation of a Global Broadcast Service reach back architecture for information dissemination management.

    OpenAIRE

    Misiewicz, Michael V. K.

    1998-01-01

    Approved for public release; distribution is unlimited The Global Broadcast Service utilizes commercial direct broadcast satellite technology tailored specifically for military application. With this service, the military directly addresses oversubscribed communication paths and introduces a quantum leap in information dissemination. However, the potential for information overload comes with the ability of this service to readily deliver multi-megabit per second data. Therefore, to make th...

  15. Commercial incineration demonstration

    International Nuclear Information System (INIS)

    Borduin, L.C.; Neuls, A.S.

    1981-01-01

    Low-level radioactive wastes (LLW) generated by nuclear utilities presently are shipped to commercial burial grounds for disposal. Substantially increasing shipping and disposal charges have sparked renewed industry interest in incineration and other advanced volume reduction techniques as potential cost-saving measures. Repeated inquiries from industry sources regarding LLW applicability of the Los Alamos controlled-air incineration (CAI) design led DOE to initiate this commercial demonstration program in FY-1980. The selected program approach to achieving CAI demonstration at a utility site is a DOE sponsored joint effort involving Los Alamos, a nuclear utility, and a liaison subcontractor. Required development tasks and responsibilities of the particpants are described. Target date for project completion is the end of FY-1985

  16. Mandatory Compensation to Commercial Agents upon Termination ...

    African Journals Online (AJOL)

    Kamil Abdu Oumer

    Abstract. The Ethiopian Commercial Code recognizes mandatory compensation if agency agreement for an indefinite period of time is terminated due to the fault of the principal; and the Draft Commercial Code is likely to maintain this approach. This comment examines the status and functions of a commercial agent as well ...

  17. Catalysts for Change: The Role of Small Business Funders in the Creation and Dissemination of Innovation.

    Science.gov (United States)

    Shic, Frederick; Smith, Daniel; Horsburgh, Brian; Hollander, Eric; Rehg, James M; Goodwin, Matthew

    2015-12-01

    A gap exists between the expanding space of technological innovations to aid those affected by autism spectrum disorders, and the actual impact of those technologies on daily lives. This gap can be addressed through a very practical path of commercialization. However, the path from a technological innovation to a commercially viable product is fraught with challenges. These challenges can be mitigated through small business funding agencies, which are, more and more, catalyzing the dissemination of innovation by fostering social entrepreneurship through capital support and venture philanthropy. This letter describes the differences and nature of these agencies, and their importance in facilitating the translational and real-world impact of technological and scientific discoveries.

  18. Dissemination of information in a networked environment

    International Nuclear Information System (INIS)

    Jayakumar, C.; Narayanan, A.

    1999-01-01

    The advent of Internet technology and its adoption by the organisations has resulted in the evolution of Intranets. Intranets ultimately use the technology to meet the information and computational needs to achieve organisational objectives and goals. Important services like E mail and Web are a handy solution to disseminate information for research and special libraries. The campus wide network and the creation of networked society are ubiquitous and an attempt has been made to extend the information service to the patrons by possible means. The role of library and information professionals in dissemination of information for the networked society is relevant and highly demanding. The right information for the right people at right time is to be achieved with available infrastructure. Few sample applications are described in this paper and the information need has to be met for the present and future networked information users. (author)

  19. [Translation and dissemination of Chinese pulse lore in the west: with its English translation and dissemination as the focus].

    Science.gov (United States)

    Liang, Xing; Lan, Feng

    2013-09-01

    Descriptive translation study approach from the perspective of polysystem theory developed by Holmes J., Even-Zohar I. and Toury G. investigates translation in its historical and cultural contexts, and thus offers a new method from a new perspective to study the history of translation of Chinese medicine. Over 300 years has passed by since the first work on Chinese pulse lore in a Western language came out in the 17th century. Many works of this topic in Western languages have got published since then. Descriptive translation study approach from the perspective of polysystem theory is applied to describe 9 representative works on Chinese pulse lore in Western languages in a comprehensive diachronic way, which takes its translation and dissemination in the West as the theme and its English translation as the focus. And the historical route and law of its translation and dissemination in the West have thus been presented: translation contents began with skills and then gradually involved classical texts; the trend is to give a comprehensive interpretation of Chinese medicine from its theoretical foundation to its clinical techniques from a cross-cultural perspective and based on classical Chinese medical texts and cultural differences between medicine East and West.

  20. Industry's Commercial Initiatives on ISS

    Science.gov (United States)

    Shields, C. E.; Kessler, C.; Lavitola, M. S.

    2002-01-01

    For more than ten years, private industry has worked to develop a commercial human space market and to create a sustainable ISS commercial utilization customer base. Before ISS assembly was underway - and long before NASA and the international space agencies began to craft ISS commercial business terms and conditions - industry planted and nurtured the seeds of interest in exploiting human space utilization for commerce. These early initiatives have yielded the impetus and framework for industry approaches to ISS commercial utilization today and for NASA's and the International Partners' planned accommodation of private sector interests and desires on the ISS. This paper chronicles major industry initiatives for commercial ISS utilization, emphasizing successful marketing and business approaches and why these approaches have a higher likelihood of success than others. It provides an overview of individual companies' initiatives, as well as collaborative efforts that cross company lines and country borders; and it assesses the relative success of each. Rather than emphasize negative issues and barriers, this paper characterizes and prioritizes actionable success factors for industry and government to make ISS commercial utilization a sustainable reality.

  1. Dissemination of research into clinical nursing literature.

    Science.gov (United States)

    Oermann, Marilyn H; Shaw-Kokot, Julia; Knafl, George J; Dowell, Jo

    2010-12-01

    The purpose of our study was to describe the dissemination of research into the clinical nursing literature. The literature provides a means of transferring knowledge from a research study through citations of the work by other authors. This was a citation analysis study to explore the dissemination of research into the clinical nursing literature, beginning with the publication of an original research study and including all of the citations to that article through 2009. The authors searched five academic nursing research journal titles, using CINAHL, for original research reports that had clinical relevance and were published between 1990-1999. The search process yielded a final data set of 28 research articles. For each of the articles, the authors searched three databases, CINAHL, Web of Science(®) and Google Scholar, to determine the citation patterns from the date of publication to August 2009. All of the research studies were cited in articles published in clinical journals although there was a wide range in the number of citations, from 3-80. The 28 research articles had a total of 759 citations; 717 (94.5%) of those citations were in articles published in clinical nursing journals. The median length of time between publication of the original study and the first citation was 1.5 years. Some of the studies were still being cited for 18 years after publication of the original work. All of the original research reports examined in this study were cited in articles in clinical journals, disseminating the research beyond the original work to reach clinicians. Clinical nursing journals keep readers up-to-date and informed about new practices in nursing and serve another important role: they disseminate research that is clinically relevant by publishing original studies and papers that cite research reports. © 2010 Blackwell Publishing Ltd.

  2. Tension Hydrothorax Related to Disseminated Endometriosis

    Directory of Open Access Journals (Sweden)

    AnnaKate Deal, MD

    2016-01-01

    Full Text Available We present the case of a 34-year-old woman presenting to the emergency department (ED with dyspnea, cough, and fever. She was found to have a tension hydrothorax and was treated with ultrasound-guided thoracentesis in the ED. Subsequent inpatient evaluation showed the patient had disseminated endometriosis. Tension hydrothorax has not been previously described in the literature as a complication of this disease.

  3. [Disseminated cryptococcosis in an immunocompetent patient].

    Science.gov (United States)

    Elkhihal, B; Hasnaoui, A; Ghfir, I; Moustachi, A; Aoufi, S; Lyagoubi, M

    2015-09-01

    Disseminated cryptococcosis is a serious opportunistic fungal infection caused by a yeast-encapsulated fungus of the genus Cryptococcus neoformans. It occurs most often in patients with a significant deficit of cellular immunity and preferentially affects the central nervous system. The skin and the lungs are the most commonly affected sites outside the neuro-subarachnoid location. We report the case of a patient apparently immunocompetent who had a disseminated cryptococcosis. The disease started with the multiple purplish skin lesions, large umbilicated on the face, groin, forearm and leg with progressively increasing volume. This symptomatology had evolved in the context of weight loss and poor general condition. The diagnosis was established by the presence of cryptococcal at the skin biopsy and cerebrospinal fluid. Research of immunosuppression common pathologies were negative. Treatment was initiated based on amphotericin B for 40 days. The patient's condition deteriorates onset of paraplegia and swallowing disorders causing death in an array of cachexia. This observation points out that disseminated cryptococcosis can occur in an immunocompetent patient. The skin lesions may be the first sign of the disease. Copyright © 2015. Published by Elsevier Masson SAS.

  4. Disseminated cutaneous histoplasmosis in an immunocompetent adult

    Directory of Open Access Journals (Sweden)

    Manoj Harnalikar

    2012-01-01

    Full Text Available Histoplasmosis, a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum var capsulatum and Histoplasma capsulatum var duboisii is endemic to many parts of the world. The clinical manifestations range from acute or chronic pulmonary infection to a progressive disseminated disease. After initial exposure to the fungus, the infection is self-limited and restricted to the lungs in 99% of healthy individuals. The remaining 1%, however, progress to either disseminated or chronic disease involving the lungs, liver, spleen, lymph nodes, bone marrow or rarely, the skin and mucous membranes. Mucocutaneous histoplasmosis is frequently reported in patients with acquired immune deficiency syndrome (AIDS, but it is rare in immunocompetent hosts. A 60-year-old male presented with asymptomatic swelling of the hard palate and crusted papules and nodules over the extremities, face and trunk. Clinically, the diagnoses of cutaneous cryptococcosis versus histoplasmosis was considered in this patient. A chest X-ray revealed hilar lymphadenopathy. Enzyme-linked immunosorbent assay (ELISA for human immunodeficiency virus (HIV was nonreactive. Skin biopsy revealed multiple tiny intracellular round yeast forms with a halo in the mid-dermis. Culture of the skin biopsy in Sabouraud′s dextrose agar showed colonies of Histoplasma capsulatum. Despite an investigation including no evidence of underlying immunosuppression was found, he was started on IV amphotericin-B (0.5 mg/kg/day. However, the patient succumbed to his disease 2 days after presentation. We report a rare case of disseminated cutaneous histoplasmosis in an immunocompetent individual.

  5. Using the printed medium to disseminate information about ...

    African Journals Online (AJOL)

    Using the printed medium to disseminate information about psychiatric disorders: original article. ... Key Words: Health information, Information material, Communication / dissemination of health information, Text-focused research, Usability testing, Message design, Printed medium, Mental health, Schizophrenia

  6. Information, Vol. 1, Number 4. Teacher Corps Dissemination Project Bulletin.

    Science.gov (United States)

    Rosenau, Fred S., Ed.

    Guidelines are provided for disseminating information on teacher corps projects. Information is given on experienced disseminators such as existing networks that are available to help in planning. Suggestions are made on targeting information and marketing. (JD)

  7. Statistical Policy Working Paper 24. Electronic Dissemination of Statistical Data

    Science.gov (United States)

    1995-11-01

    The report, Statistical Policy Working Paper 24, Electronic Dissemination of Statistical Data, includes several topics, such as Options and Best Uses for Different Media Operation of Electronic Dissemination Service, Customer Service Programs, Cost a...

  8. The Role of Skills Dissemination in Counseling Psychology

    Science.gov (United States)

    Hurst, James C.

    1977-01-01

    Skills dissemination refers to therapeutic interventions which train individuals in human development process skill for their own benefit and that of those around them. The author discusses prerequisites to dissemination, skills or content satisfying these prerequisites, methods for dissemination, and necessary education and training for…

  9. Community Based Approach to Wind Energy Information Dissemination

    Energy Technology Data Exchange (ETDEWEB)

    Innis, S.

    2003-09-26

    The purpose of the Department of Energy's grant was to transfer to New Mexico and Utah a national award-winning market-based strategy to aggregate demand for wind energy. Their experiences over the past few years in New Mexico and utah have been quite different. In both states they have developed stronger relationships with utilities and policymakers which will increase the effectiveness of the future advocacy efforts.

  10. Lead Farmers Approach in Disseminating Improved Tef Production ...

    African Journals Online (AJOL)

    Abate

    that the two highest production costs were labor (56%) and fertilizer (23%). ... Cost data collection and monitoring during the growing season were done by farmers using recording formats for farm operations. To this effect, a day-long training .... population usually has a direct positive correlation with high plant biomass.

  11. Study to assess the feasibility of scaling up the powder metallurgy approach for the fabrication of commercial Nb3Sn filamentary superconductors

    International Nuclear Information System (INIS)

    1977-01-01

    A preliminary assessment was made of the feasibility of scaling up the laboratory techniques of making filamentary Nb 3 Sn superconductors using powder metallurgy to commercial fabrication process. The purpose of the effort is divided into two tasks. The first one is to demonstrate that sintered niobium rods infiltrated with tin can be reduced in area of approximately 10 4 . The second task pertains to the extrusion by conventional manner a copper billet containing several sintered rods each encapsulated in tantalum. The ultimate goal of the project is to establish optimal processing parameters that are suitable for the production of long lengths of fully stabilized, large current and high field conductors

  12. Technology delivery and Dissemination Through Community-Based Organisations

    International Nuclear Information System (INIS)

    Bukachi, S.

    2002-01-01

    Utilisation of existing community groups, which already have their agenda and organisational structure, is one of the ways of ensuring sustainability of tsetse and trypanosomiasis control programs. The aim of this study was to assess and document the organisational structures and capacity of the identified groups in Busia with view to using them as entry and dispersal points for tsetse technology transfer. focus groups discussions and key informant interview were held with members of the organisations dealing in livestock/related activities to find out the historical profiles, goals and missions,compositions of the groups and their impact on the community. Qualitative approach was used in describing and discussing the data collected. Findings reveal that most organisations were formed to uplift the socio-economic status of members and as a result, engage in various activities to generate income for group. The common methods of tsetse control used by some of the groups were, bush clearing, use of impregnated nets (for the zero grazing units), use of drugs, spraying and pour-on. Groups that were internally initiated seemed to be more active and sustainable than groups that were externally initiated. On average, the groups reported that they were in position to reach between 100 and 1000 people in the community per day. Thus, these groups can be resourceful in terms of technology/information dissemination since they have a good linkage with the community. Such organisations can be used as channels to disseminate livestock research outputs to the wider community

  13. A combined Surface Enhanced Raman Spectroscopy (SERS)/UV-vis approach for the investigation of dye content in commercial felt tip pens inks.

    Science.gov (United States)

    Saviello, Daniela; Trabace, Maddalena; Alyami, Abeer; Mirabile, Antonio; Giorgi, Rodorico; Baglioni, Piero; Iacopino, Daniela

    2018-05-01

    The development of protocols for the protection of the large patrimony of works of art created by felt tip pen media since the 1950's requires detailed knowledge of the main dyes constituting commercial ink mixtures. In this work Surface Enhanced Raman Scattering (SERS) and UV-vis spectroscopy were used for the first time for the systematic identification of dye composition in commercial felt tip pens. A large selection of pens comprising six colors of five different brands was analyzed. Intense SERS spectra were obtained for all colors, allowing identification of main dye constituents. Poinceau 4R and Eosin dyes were found to be the main constituents of red and pink colors; Rhodamine and Tartrazine were found in orange and yellow colors; Erioglaucine was found in green and blue colors. UV-vis analysis of the same inks was used to support SERS findings but also to unequivocally assign some uncertain dye identifications, especially for yellow and orange colors. The spectral data of all felt tip pens collected through this work were assembled in a database format. The data obtained through this systematic investigation constitute the basis for the assembly of larger reference databases that ultimately will support the development of conservation protocols for the long term preservation of modern art collections. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. Dissemination of Earth Remote Sensing Data for Use in the NOAA/NWS Damage Assessment Toolkit

    Science.gov (United States)

    Molthan, Andrew; Burks, Jason; Camp, Parks; McGrath, Kevin; Bell, Jordan

    2015-01-01

    The National Weather Service has developed the Damage Assessment Toolkit (DAT), an application for smartphones and tablets that allows for the collection, geolocation, and aggregation of various damage indicators that are collected during storm surveys. The DAT supports the often labor-intensive process where meteorologists venture into the storm-affected area, allowing them to acquire geotagged photos of the observed damage while also assigning estimated EF-scale categories based upon their observations. Once the data are collected, the DAT infrastructure aggregates the observations into a server that allows other meteorologists to perform quality control and other analysis steps before completing their survey and making the resulting data available to the public. In addition to in-person observations, Earth remote sensing from operational, polar-orbiting satellites can support the damage assessment process by identifying portions of damage tracks that may be missed due to road limitations, access to private property, or time constraints. Products resulting from change detection techniques can identify damage to vegetation and the land surface, aiding in the survey process. In addition, higher resolution commercial imagery can corroborate ground-based surveys by examining higher-resolution commercial imagery. As part of an ongoing collaboration, NASA and NOAA are working to integrate near real-time Earth remote sensing observations into the NOAA/NWS Damage Assessment Toolkit. This presentation will highlight recent developments in a streamlined approach for disseminating Earth remote sensing data via web mapping services and a new menu interface that has been integrated within the DAT. A review of current and future products will be provided, including products derived from MODIS and VIIRS for preliminary track identification, along with conduits for higher-resolution Landsat, ASTER, and commercial imagery as they become available. In addition to tornado damage

  15. Commentary: pediatric eHealth interventions: common challenges during development, implementation, and dissemination.

    Science.gov (United States)

    Wu, Yelena P; Steele, Ric G; Connelly, Mark A; Palermo, Tonya M; Ritterband, Lee M

    2014-07-01

    To provide an overview of common challenges that pediatric eHealth researchers may encounter when planning, developing, testing, and disseminating eHealth interventions along with proposed solutions for addressing these challenges. The article draws on the existing eHealth literature and the authors' collective experience in pediatric eHealth research. The challenges associated with eHealth interventions and their proposed solutions are multifaceted and cut across a number of areas from eHealth program development through dissemination. Collaboration with a range of individuals (e.g., multidisciplinary colleagues, commercial entities, primary stakeholders) is the key to eHealth intervention success. To ensure adequate resources for design, development, and planning for sustainability, a number of public and private sources of funding are available. A study design that addresses ethical concerns and security issues is critical to ensure scientific integrity and intervention dissemination. Table I summarizes key issues to consider during eHealth intervention development, testing, and dissemination. © The Author 2014. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. The implementation of knowledge dissemination in the prevention of occupational skin diseases.

    Science.gov (United States)

    Wilke, A; Bollmann, U; Cazzaniga, S; Hübner, A; John, S M; Karadzinska-Bislimovska, J; Mijakoski, D; Šimić, D; Simon, D; Sonsmann, F; Stoleski, S; Weinert, P; Wulfhorst, B

    2018-03-01

    Occupational skin diseases (OSD) have a high medical, social, economic and political impact. Knowledge dissemination from research activities to key stakeholders involved in health care is a prerequisite to make prevention effective. To study and prioritize different activity fields and stakeholders that are involved in the prevention of OSD, to reflect on their inter-relationships, to develop a strategic approach for knowledge dissemination and to develop a hands-on tool for OSD prevention projects METHODS: Seven different activity fields that are relevant in the prevention of OSD have been stepwise identified. This was followed by an impact analysis. Fifty-five international OSD experts rated the impact and the influence of the activity fields for the prevention of OSD with a standardized questionnaire. Activity fields identified to have a high impact in OSD prevention are the political system, mass media and industry. The political system has a strong but more indirect effect on the general population via the educational system, local public health services or the industry. The educational system, mass media, industry and local public health services have a strong direct impact on the OSD 'at risk' worker. Finally, a hands-on tool for future OSD prevention projects has been developed that addresses knowledge dissemination and different stakeholder needs. Systematic knowledge dissemination is important to make OSD prevention more effective and to close the gap between research and practice. This study provides guidance to identify stakeholders, strategies and dissemination channels for systematic knowledge dissemination which need to be adapted to country-specific structures, for example the social security system and healthcare systems. A key for successful knowledge dissemination is building linkages among different stakeholders, building strategic partnerships and gaining their support right from the inception phase of a project. © 2017 European Academy of

  17. Acquired immunodeficiency syndrome manifested as disseminated cryptococcosis.

    Science.gov (United States)

    Pittard, G; Seger, D

    1985-01-01

    A 32-year-old male homosexual presented to the emergency department (ED) with the clinical picture of a nonspecific illness. While in the ED, he experienced a first-time seizure. Computed tomography (CT) showed an enhancing mass lesion. Antibacterial therapy was started and continued until a second lumbar puncture (LP), 36 hours after admission, showed distinct yeast forms. Subsequent institution of appropriate therapy did not prevent the patient's death. The cause of death was disseminated cryptococcosis secondary to acquired immunodeficiency syndrome (AIDS).

  18. Disseminated coccidoidomycosis in a koala (Phascolarctos cinereus).

    Science.gov (United States)

    Burgdorf-Moisuk, Anne; Stalis, Ilse H; Pye, Geoffrey W

    2012-03-01

    A16-yr-old male koala (Phascolarctos cinereus) presented for nonspecific signs of illness and weight loss. Despite 2 mo of diagnostics and supportive care, the koala's health declined and euthanasia was elected. On histopathologic examination, lesions containing fungal organisms morphologically consistent with coccidioidomycosis were found in the lung, liver, spleen, kidney, lymph node, heart, eye, and bone marrow. Although disseminated infection was present, the koala was IgM and IgG seronegative for Coccidioides spp. 1 mo prior to euthanasia.

  19. Disseminated peritoneal leiomyomatosis mimicking ovarian torsion

    Directory of Open Access Journals (Sweden)

    Chau-Yang Tyan

    2015-01-01

    Full Text Available The presentation of disseminated peritoneal leiomyomatosis (DPL can be misleading. Herein, we present the case of a 42-year-old nulliparous female who had previously undergone a total hysterectomy and presented with an acute abdomen. A presumptive diagnosis of ovarian torsion was made based on the clinical findings and an ultrasonographic examination. A diagnostic laparoscopy was performed immediately. DPL was subsequently diagnosed based on an intra-operative frozen section during surgical exploration and the final histopathologic examination. This case illustrates an atypical presentation of DPL mimicking ovarian torsion.

  20. Disseminated lupus vulgaris: a case report.

    Science.gov (United States)

    Can, Burce; Zindanci, Ilkin; Turkoglu, Zafer; Kavala, Mukaddes; Ulucay, Vasfiye; Demir, Filiz Topaloglu

    2014-01-01

    Lupus vulgaris is a secondary form of cutaneous tuberculosis which persists for years if not treated. The head and neck are the most commonly affected sites. While less frequently arms and legs, and rarely the trunk and the scalp are involved. Herein, we describe a 73-year-old man with a 5-year history of slowly growing, atrophic, some eroded and ulcerated, red-brown plaques on his forehead, nose, cheeks, ear lobes, trunk and extremites. All of his disseminated lesions healed after antituberculosis therapy.

  1. Study to assess the feasibility of scaling up the powder metallurgy approach for the fabrication of commercial Nb/sub 3/Sn filamentary superconductors

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-09

    A preliminary assessment was made of the feasibility of scaling up the laboratory techniques of making filamentary Nb/sub 3/Sn superconductors using powder metallurgy to commercial fabrication process. The purpose of the effort is divided into two tasks. The first one is to demonstrate that sintered niobium rods infiltrated with tin can be reduced in area of approximately 10/sup 4/. The second task pertains to the extrusion by conventional manner a copper billet containing several sintered rods each encapsulated in tantalum. The ultimate goal of the project is to establish optimal processing parameters that are suitable for the production of long lengths of fully stabilized, large current and high field conductors.

  2. Climate change education in informal settings: Using boundary objects to frame network dissemination

    Science.gov (United States)

    Steiner, Mary Ann

    This study of climate change education dissemination takes place in the context of a larger project where institutions in four cities worked together to develop a linked set of informal learning experiences about climate change. Each city developed an organizational network to explore new ways to connect urban audiences with climate change education. The four city-specific networks shared tools, resources, and knowledge with each other. The networks were related in mission and goals, but were structured and functioned differently depending on the city context. This study illustrates how the tools, resources, and knowledge developed in one network were shared with networks in two additional cities. Boundary crossing theory frames the study to describe the role of objects and processes in sharing between networks. Findings suggest that the goals, capacity and composition of networks resulted in a different emphasis in dissemination efforts, in one case to push the approach out to partners for their own work and in the other to pull partners into a more collaborative stance. Learning experiences developed in each city as a result of the dissemination reflected these differences in the city-specific emphasis with the push city diving into messy examples of the approach to make their own examples, and the pull city offering polished experiences to partners in order to build confidence in the climate change messaging. The networks themselves underwent different kinds of growth and change as a result of dissemination. The emphasis on push and use of messy examples resulted in active use of the principles of the approach and the pull emphasis with polished examples resulted in the cultivation of partnerships with the hub and the potential to engage in the educational approach. These findings have implications for boundary object theory as a useful grounding for dissemination designs in the context of networks of informal learning organizations to support a shift in

  3. Dissemination of health technology assessments: identifying the visions guiding an evolving policy innovation in Canada.

    Science.gov (United States)

    Lehoux, Pascale; Denis, Jean-Louis; Tailliez, Stéphanie; Hivon, Myriam

    2005-08-01

    Health technology assessment (HTA) has received increasing support over the past twenty years in both North America and Europe. The justification for this field of policy-oriented research is that evidence about the efficacy, safety, and cost-effectiveness of technology should contribute to decision and policy making. However, concerns about the ability of HTA producers to increase the use of their findings by decision makers have been expressed. Although HTA practitioners have recognized that dissemination activities need to be intensified, why and how particular approaches should be adopted is still under debate. Using an institutional theory perspective, this article examines HTA as a means of implementing knowledge-based change within health care systems. It presents the results of a case study on the dissemination strategies of six Canadian HTA agencies. Chief executive officers and executives (n = 11), evaluators (n = 19), and communications staff (n = 10) from these agencies were interviewed. Our results indicate that the target audience of HTA is frequently limited to policy makers, that three conflicting visions of HTA dissemination coexist, that active dissemination strategies have only occasionally been applied, and that little attention has been paid to the management of diverging views about the value of health technology. Our discussion explores the strengths, limitations, and trade-offs associated with the three visions. Further efforts should be deployed within agencies to better articulate a shared vision and to devise dissemination strategies that are consistent with this vision.

  4. Accelerating the commercialization on new technologies. [free market operation of federal alternate energy sources programs

    Science.gov (United States)

    Kuehn, T. J.; Nawrocki, P. M.

    1978-01-01

    It is suggested that federal programs for hastening the adoption of alternative energy sources must operate within the free market structure. Five phases of the free market commercialization process are described. Federal role possibilities include information dissemination and funding to stimulate private sector activities within these five phases, and federally sponsored procedures for accelerating commercialization of solar thermal small power systems are considered.

  5. New trends in knowledge dissemination: TED Talks

    Directory of Open Access Journals (Sweden)

    Giuseppina Scotto di Carlo

    2014-05-01

    Full Text Available This paper investigates the key elements of ethos, pathos and logos linguistic strategies as some main features of TED (Technology, Entertainment, Design Talks, popularizing speeches aiming at Knowledge Dissemination. Through a comparison between the TED Talk ‘HIV - How to fight an epidemic of bad laws’, by Shereen El-Feki (2012a, and another speech held by the same author at the  2012 Symposia The Global Commission on HIV and the Law, addressed to specialists, the paper analyses TED Talks as an innovative tool of popularization, which breaches the typical triangularisation ‘scientist-mediator-audience’, bringing scientists directly into contact with their audiences. Drawing upon Aristotle’s three pillars of rhetoric, the paper analyses the strategies used to establish the ethos of the speech, by proposing a topic as morally worth of spreading; pathos, by creating a direct contact with the public; and logos, investigated through an analysis of the elements used to recontextualise scientific discourses into popularized speeches. The analysis suggests that TED Talks are a recodification, not a mere translation of texts; they are a means to disseminate knowledge reducing the asymmetry between audiences and scientists.

  6. Disseminated intravascular coagulation in solid tumors

    International Nuclear Information System (INIS)

    Terzieff, V.; Alonso, I.; Vázquez, A.

    2004-01-01

    It is estimated that 20-25% of cases of disseminated intravascular coagulation (DIC) relate to an underlying neoplasia primarily hematologic. It is estimated that about 5% of patients with solid tumors have CID clinic, although the incidence of subclinical alterations is much higher. The CID is not limited to the activation of the coagulation cascade, which leads to bleeding micro thrombosis and consumption of coagulation factors. Solid tumors are frequently associated adenocarcinomas producers mucin (especially gastric), usually in the context of a disseminated disease. The mucin may act as a promoter of the cascade, but probably it is a multi-event. High levels of TNF to produced by the tumor mass and chemotherapy-induced cell lysis have Also linked. Although the bleeding is usually oriented diagnosis, the most frequent cause of death is thrombosis. There are no specific tests for diagnosis. Elevated levels of D-dimer and products oriented fibrinogen degradation diagnosis. No reduction fibrinogen and almost always, one thrombocytopenia consumption. Treatment is complex and there is no consensus on many points. To recover the lost factors for consumption, it is recommended to use fresh frozen plasma and / or washed red blood cells. the heparin anticoagulation low dose is indicated since the disease causal can not be controlled quickly, but should not be initiated if there thrombocytopenia 50.000.El under profuse bleeding can require the use of tranexamic acid or EACA. Acute DIC, the case of our patient, is rare and very serious

  7. ANENT Activities for Knowledge Sharing and Dissemination

    International Nuclear Information System (INIS)

    Nam, Y.; Rho, S.; Chanyota, S.; Hanamitsu, K.

    2016-01-01

    Full text: This paper describes the main activities and achievement of the Asian Network for Education in Nuclear Technology (ANENT) related to knowledge sharing and dissemination in the Asia and Pacific region, and how it has strengthened its networks. Since the establishment of ANENT in 2004, the basic framework and infrastructure of collaboration among universities, R&D organizations, and training institutes have been established and improved. The ANENT web-portal was opened in 2004 to share, exchange, and disseminate information and experiences of interest for the educational communities in the region. A regional learning management system (LMS) was installed in the Korean server as an innovative tool for facilitating and promoting e-Learning. Using this LMS, six e-Training courses and five Train the Trainer (TTT) courses were implemented. In 2016, a newly launched four year IAEA Technical Cooperation project will facilitate ANENT activities to strengthen the nuclear knowledge management (NKM), develop the human resources and enhance young nuclear scientists’ and public understanding of nuclear science and technology. Internet technology will help implement these activities by providing effective and efficient methods and tools and use the regional scientific infrastructures such as research reactors for nuclear education and training through regional LMS. (author

  8. Hydrogen Technical Analysis -- Dissemination of Information

    Energy Technology Data Exchange (ETDEWEB)

    George Kervitsky, Jr.

    2006-03-20

    SENTECH is a small energy and environmental consulting firm providing technical, analytical, and communications solutions to technology management issues. The activities proposed by SENTECH focused on gathering and developing communications materials and information, and various dissemination activities to present the benefits of hydrogen energy to a broad audience while at the same time establishing permanent communications channels to enable continued two-way dialog with these audiences in future years. Effective communications and information dissemination is critical to the acceptance of new technology. Hydrogen technologies face the additional challenge of safety preconceptions formed primarily as a result of the crash of the Hindenburg. Effective communications play a key role in all aspects of human interaction, and will help to overcome the perceptual barriers, whether of safety, economics, or benefits. As originally proposed SENTECH identified three distinct information dissemination activities to address three distinct but important audiences; these formed the basis for the task structure used in phases 1 and 2. The tasks were: (1) Print information--Brochures that target the certain segment of the population and will be distributed via relevant technical conferences and traditional distribution channels. (2) Face-to-face meetings--With industries identified to have a stake in hydrogen energy. The three industry audiences are architect/engineering firms, renewable energy firms, and energy companies that have not made a commitment to hydrogen (3) Educational Forums--The final audience is students--the future engineers, technicians, and energy consumers. SENTECH will expand on its previous educational work in this area. The communications activities proposed by SENTECH and completed as a result of this cooperative agreement was designed to compliment the research and development work funded by the DOE by presenting the technical achievements and validations

  9. Software agents for the dissemination of remote terrestrial sensing data

    Science.gov (United States)

    Toomey, Christopher N.; Simoudis, Evangelos; Johnson, Raymond W.; Mark, William S.

    1994-01-01

    Remote terrestrial sensing (RTS) data is constantly being collected from a variety of space-based and earth-based sensors. The collected data, and especially 'value-added' analyses of the data, are finding growing application for commercial, government, and scientific purposes. The scale of this data collection and analysis is truly enormous; e.g., by 1995, the amount of data available in just one sector, NASA space science, will reach 5 petabytes. Moreover, the amount of data, and the value of analyzing the data, are expected to increase dramatically as new satellites and sensors become available (e.g., NASA's Earth Observing System satellites). Lockheed and other companies are beginning to provide data and analysis commercially. A critical issue for the exploitation of collected data is the dissemination of data and value-added analyses to a diverse and widely distributed customer base. Customers must be able to use their computational environment (eventually the National Information Infrastructure) to obtain timely and complete information, without having to know the details of where the relevant data resides and how it is accessed. Customers must be able to routinely use standard, widely available (and, therefore, low cost) analyses, while also being able to readily create on demand highly customized analyses to make crucial decisions. The diversity of user needs creates a difficult software problem: how can users easily state their needs, while the computational environment assumes the responsibility of finding (or creating) relevant information, and then delivering the results in a form that users understand? A software agent is a self-contained, active software module that contains an explicit representation of its operational knowledge. This explicit representation allows agents to examine their own capabilities in order to modify their goals to meet changing needs and to take advantage of dynamic opportunities. In addition, the explicit representation

  10. Performances of a Date Dissemination Code on Telephone Lines Using Commercial Modems

    Science.gov (United States)

    1992-12-01

    M. Malcangi, Il modem, teoria , funzionomento e applicazioni, Jackson, 1989. [8] S. Leschiutta, "Long term accuracy of time comparisons via TV...account. We have several inquiries about this kind of service in the 1 second to 0.1 second region . M. Weiss: So we have jumped from the nanosecond

  11. Dissemination of Climate Model Output to the Public and Commercial Sector

    Energy Technology Data Exchange (ETDEWEB)

    Robert Stockwell, PhD

    2010-09-23

    Climate is defined by the Glossary of Meteorology as the mean of atmospheric variables over a period of time ranging from as short as a few months to multiple years and longer. Although the term climate is often used to refer to long-term weather statistics, the broader definition of climate is the time evolution of a system consisting of the atmosphere, hydrosphere, lithosphere, and biosphere. Physical, chemical, and biological processes are involved in interactions among the components of the climate system. Vegetation, soil moisture, and glaciers are part of the climate system in addition to the usually considered temperature and precipitation (Pielke, 2008). Climate change refers to any systematic change in the long-term statistics of climate elements (such as temperature, pressure, or winds) sustained over several decades or longer. Climate change can be initiated by external forces, such as cyclical variations in the Earth's solar orbit that are thought to have caused glacial and interglacial periods within the last 2 million years (Milankovitch, 1941). However, a linear response to astronomical forcing does not explain many other observed glacial and interglacial cycles (Petit et al., 1999). It is now understood that climate is influenced by the interaction of solar radiation with atmospheric greenhouse gasses (e.g., carbon dioxide, chlorofluorocarbons, methane, nitrous oxide, etc.), aerosols (airborne particles), and Earth's surface. A significant aspect of climate are the interannual cycles, such as the El Nino La Nina cycle which profoundly affects the weather in North America but is outside the scope of weather forecasts. Some of the most significant advances in understanding climate change have evolved from the recognition of the influence of ocean circulations upon the atmosphere (IPCC, 2007). Human activity can affect the climate system through increasing concentrations of atmospheric greenhouse gases, air pollution, increasing concentrations of aerosol, and land alteration. A particular concern is that atmospheric levels of CO{sub 2} may be rising faster than at any time in Earth's history, except possibly following rare events like impacts from large extraterrestrial objects (AMS, 2007). Atmospheric CO{sub 2} concentrations have increased since the mid-1700s through fossil fuel burning and changes in land use, with more than 80% of this increase occurring since 1900. The increased levels of CO{sub 2} will remain in the atmosphere for hundreds to thousands of years. The complexity of the climate system makes it difficult to predict specific aspects of human-induced climate change, such as exactly how and where changes will occur, and their magnitude. The Intergovernmental Panel for Climate Change (IPCC) was established by World Meteorological Organization (WMO) and the United Nations in 1988. The IPCC was tasked with assessing the scientific, technical and socioeconomic information needed to understand the risk of human-induced climate change, its observed and projected impacts, and options for adaptation and mitigation. The IPCC concluded in its Fourth Assessment Report (AR4) that warming of the climate system is unequivocal, and that most of the observed increase in globally averaged temperatures since the mid-20th century is very likely due to the observed increased in anthropogenic greenhouse gas concentrations (IPCC, 2007).

  12. Commercial microwave space power

    International Nuclear Information System (INIS)

    Siambis, J.; Gregorwich, W.; Walmsley, S.; Shockey, K.; Chang, K.

    1991-01-01

    This paper reports on central commercial space power, generating power via large scale solar arrays, and distributing power to satellites via docking, tethering or beamed power such as microwave or laser beams, that is being investigated as a potentially advantageous alternative to present day technology where each satellite carries its own power generating capability. The cost, size and weight for electrical power service, together with overall mission requirements and flexibility are the principal selection criteria, with the case of standard solar array panels based on the satellite, as the reference point. This paper presents and investigates a current technology design point for beamed microwave commercial space power. The design point requires that 25 kW be delivered to the user load with 30% overall system efficiency. The key elements of the design point are: An efficient rectenna at the user end; a high gain, low beam width, efficient antenna at the central space power station end, a reliable and efficient cw microwave tube. Design trades to optimize the proposed near term design point and to explore characteristics of future systems were performed. Future development for making the beamed microwave space power approach more competitive against docking and tethering are discussed

  13. Communication and dissemination strategies to facilitate the use of health-related evidence.

    Science.gov (United States)

    McCormack, Lauren; Sheridan, Stacey; Lewis, Megan; Boudewyns, Vanessa; Melvin, Cathy L; Kistler, Christine; Lux, Linda J; Cullen, Katherine; Lohr, Kathleen N

    2013-11-01

    This review examined how to best communicate and disseminate evidence, including uncertain evidence, to inform health care decisions. The review focused on three primary objectives--comparing the effectiveness of: (1) communicating evidence in various contents and formats that increase the likelihood that target audiences will both understand and use the information (KQ 1); (2) a variety of approaches for disseminating evidence from those who develop it to those who are expected to use it (KQ 2); and (3) various ways of communicating uncertainty-associated health-related evidence to different target audiences (KQ 3). A secondary objective was to examine how the effectiveness of communication and dissemination strategies varies across target audiences, including evidence translators, health educators, patients, and clinicians. We searched MEDLINE®, the Cochrane Library, Cochrane Central Trials Registry, PsycINFO®, and the Web of Science. We used a variety of medical subject headings (MeSH terms) and major headings, and used free-text and title and abstract text-word searches. The search was limited to studies on humans published from 2000 to March 15, 2013, for communication and dissemination, given the prior systematic reviews, and from 1966 to March 15, 2013, for communicating uncertainty. We used standard Evidence-based Practice Center methods of dual review of abstracts, full-text articles, and abstractions, and quality ratings and group consensus to resolve disagreements. We used group consensus to grade strength of evidence. The search identified 4,152 articles (after removing duplicates) for all three KQs. After dual review at the title/abstract stage and full-text review stage, we retained 61 articles that directly (i.e., head to head) compared strategies to communicate and disseminate evidence. Across the KQs, many of the comparisons yielded insufficient evidence to draw firm conclusions. For KQ 1, we found that investigators frequently blend more than

  14. Commercial Buildings Characteristics, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-29

    Commercial Buildings Characteristics 1992 presents statistics about the number, type, and size of commercial buildings in the United States as well as their energy-related characteristics. These data are collected in the Commercial Buildings Energy Consumption Survey (CBECS), a national survey of buildings in the commercial sector. The 1992 CBECS is the fifth in a series conducted since 1979 by the Energy Information Administration. Approximately 6,600 commercial buildings were surveyed, representing the characteristics and energy consumption of 4.8 million commercial buildings and 67.9 billion square feet of commercial floorspace nationwide. Overall, the amount of commercial floorspace in the United States increased an average of 2.4 percent annually between 1989 and 1992, while the number of commercial buildings increased an average of 2.0 percent annually.

  15. Dissemination of research in clinical nursing journals.

    Science.gov (United States)

    Oermann, Marilyn H; Nordstrom, Cheryl K; Wilmes, Nancy A; Denison, Doris; Webb, Sue A; Featherston, Diane E; Bednarz, Hedi; Striz, Penelope; Blair, Darlene A; Kowalewski, Kathleen

    2008-01-01

    The purposes of the study were to describe the extent of research, clinical and evidence-based practice articles published in clinical nursing journals and to explore the communication of research and practice knowledge in the clinical nursing literature using citation analysis. For nursing research to have an impact on clinical practice and build evidence for practice, findings from research must transfer into the clinical practice literature. By analysing the extent of research published in clinical nursing journals, the citations in those articles, and other characteristics of the nursing literature, we can learn more about the linkages between research and practice in nursing. This was a descriptive study of 768 articles and 18901 citations in those articles. Feature articles were classified into four groups - (i) original research reports; (ii) clinical practice articles (non-data based papers on a clinical topic); (iii) systematic reviews, integrative literature reviews, guidelines and papers describing evidence-based practice; and (iv) others. Each citation was then examined to determine if it was a reference to a research study or to a document on clinical practice. Nearly a third of the articles in clinical nursing journals were reports on research studies; another third addressed clinical practice. Of the 14232 citations analysed in clinical nursing journals, 6142 were to research reports (43.2%) and about the same number of citations were to clinical documents (n = 5844, 41.1%). Medical research articles were cited most frequently - 27.1% of the citations in clinical journal articles. Nursing research articles were only 7.6% of the cited documents in clinical publications. Dissemination of research findings in the clinical nursing literature occurred at two levels: through articles that reported studies of potential value to the nurse's practice and citations to research publications within articles. Relevance to clinical practice. Disseminating research

  16. Selective dissemination and indexing of scientific information.

    Science.gov (United States)

    Schneider, J H

    1971-07-23

    Selective dissemination of information to individuals provides a new and promising method for keeping abreast of current scientific information. Since SDI services are directed to the information needs of each individual, they are a significant step beyond grouporiented services and products, which require considerable expenditure of effort by each user as he sorts useful information from trash. However, SDI systems do require a high degree of precision in matching scientists against documents. They must operate more efficiently and economically than many current systems which occasionally provide a useful item of information to users. To meet these stringent requirements for quality, precision, efficiency, and economy, more research must be devoted to comparing and improving indexing methods, which are the basic component of all information storage and retrieval systems. It is incredible that so much money has been spent on the development and operation of scientific information systems before basic data on the comparative performance of various indexing methods have been gathered, analyzed, and confirmed by multiple investigators. The design of an effective information system would seem to require this type of basic knowledge, just as basic properties of alternative materials must be known before an engineer can design a building, bridge, or factory. Yet, except for the few studies mentioned in the previous section, research on indexing methods has been greatly neglected. Bourne's comment about studies of indexing languages is still an appropriate description of the situation: "In almost all the experimental reports, the investigator worked with an indexing language different than that of other experimenters. Consequently, no one has ever had his test results verified, or expanded, or made more precise by another experimenter" (47). Most existing information systems are based on keyword indexing, with concepts broken into isolated terms during input operations

  17. Disseminated gonococcal infection: an unusual presentation

    Directory of Open Access Journals (Sweden)

    Saroj Lohani

    2016-07-01

    Full Text Available Gonococcus typically affects the mucosal surfaces but in rare cases can spread to bloodstream causing disseminated gonococcal infection (DGI. The usual presentation of DGI is rash, polyarthralgia, and tenosynovitis. We present the case of a 23-year-old female who presented to our hospital with pustular rash and tenosynovitis of hand and was sent home on Augmentin. Her symptoms worsened despite treatment and she presented back to the ED. On investigation, she was found to have DGI and was appropriately treated. DGI should be kept in mind in sexually active youngsters who have only one or two features of the classic triad of rash, tenosynovitis, and arthritis. Timely management and appropriate treatment of DGI is very important to avoid complications and morbidity.

  18. Quinine-Induced Disseminated Intravascular Coagulation

    Directory of Open Access Journals (Sweden)

    Firas Abed

    2016-01-01

    Full Text Available Every drug comes with some side effect. It is the benefit/risk ratio that determines the medical use of the drug. Quinine, a known antimalarial drug, has been used for nocturnal leg cramps since the 1930s; it is associated with severe life-threatening hematological and cardiovascular side effects. Disseminated intravascular coagulation (DIC, albeit rare, is a known coagulopathy associated with Quinine. It is imperative to inquire about the Quinine intake in medication history in patients with coagulopathy, as most patients still consider it a harmless home remedy for nocturnal leg cramps. In this report, we present a case of coagulopathy in a middle-aged woman, who gave a history of taking Quinine for nocturnal leg cramps, as her home remedy. Early identification of the offending agent led to the diagnosis, prompt discontinuation of the medication, and complete recovery and prevented the future possibility of recurrence.

  19. [Case report: disseminated cutaneous leishmaniasis (LCD)].

    Science.gov (United States)

    Mancheno-Valencia, Alexandra; Cabezas-Arteaga, Julia; Sacoto-Aizaga, Ketty; Arenas-Guzmáno, Roberto

    The World Health Organization (WHO) has classified leishmaniasis as an uncontrolled and emerging disease. In Ecuador, the only anecdotal cases of diffuse cutaneous leishmaniasis were recorded in 1994 and have not been formally published. This form can be differentiated from classical localized cutaneous leishmaniasis by the number of injuries, the clinical type of the main elementary lesions (papular and acneform), and a weak response to standard treatments. The case we report is a 34-year-old woman who presented with disseminated nodular lesions and ulcers of various sizes with erythematous edges and scars. We report the case and review diffuse cutaneous leishmaniasis and the differences that can be found with the other cutaneous variants. The diagnosis requires to be considered by primary care physicians in endemic areas and specialists, taking into account that this presentation can also occur in immunocompetent hosts.

  20. Collection, verification, sharing and dissemination of data

    DEFF Research Database (Denmark)

    Saarnak, Christopher; Utzinger, Jürg; Kristensen, Thomas K.

    2013-01-01

    that would enable all project partners to have access through a password protected Internet-based data portal. This required anonymous agreement on several common standardised sample forms, ranging from the mundane but important issue of using the same units of measurement to more complex challenges......The scientific community is charged with growing demands regarding the management of project data and outputs and the dissemination of key results to various stakeholders. We discuss experiences and lessons from CONTRAST, a multidisciplinary alliance that had been funded by the European Commission...... over a 4-year period, in order to optimize schistosomiasis control and transmission surveillance in sub-Saharan Africa. From the start, project partners from Europe and Africa set out an ambitious goal: to sample data following standard protocols at all field sites and then sharing the data in a way...

  1. Alpha particles for treatment of disseminated melanoma

    Energy Technology Data Exchange (ETDEWEB)

    Link, E.M. [London University (United Kingdom)

    2010-07-01

    Invading melanoma spreads to local and unpredictable distant location at the early stages of its development. It is justifiable, therefore, to classify the disease as a systemic disorder. This requires a systemic treatment that reaches all melanoma cells irrespective of whether they are singly dispersed and in circulation or already forming solid tumours of various sizes. Targeted radiotherapy affects directly and selectively cancer cells provided an appropriate radionuclide and its carrier are chosen. Melanoma is a pigmented tumour. Methylene blue (MTB)) accumulates selectively in melanoma cells due to its exceptionally high affinity to melanin. MTB serves, therefore, as a carrier for radionuclides. {sup 211}At-MTB has proved to be particularly effective in treating disseminated melanoma when administered systemically and, at the same time, non-toxic to normal non-pigmented and pigmented organs. (authors)

  2. Alpha particles for treatment of disseminated melanoma

    Energy Technology Data Exchange (ETDEWEB)

    Link, E.M. [London Univ. (United Kingdom)

    2010-11-15

    Invading melanoma spreads to local and unpredictable distant location at the early stages of its development. It is justifiable, therefore to classify the disease as a systemic disorder. This requires a systemic treatment that reaches all melanoma cells irrespective of whether they are singly dispersed and in circulation or already forming solid tumours of various sizes. Targeted radiotherapy affects directly and selectively cancer cells provided an appropriate radionuclide and its carrier are chosen. Melanoma is a pigmented tumour. Methylene blue (MTB) accumulates selectively in melanoma cells due to its exceptionally high affinity to melanin. MTB serves, therefore, as a carrier for radionuclides. {sup 211}At-MTB has proved to be particularly effective in treating disseminated melanoma when administered systemically and, at the same time, non-toxic to normal non-pigmented and pigmented organs. (author)

  3. Chronic Disseminated Intravascular Coagulation: A Case Report

    Directory of Open Access Journals (Sweden)

    Md Abul Kalam Azad

    2009-11-01

    Full Text Available In health there is a balance between the coagulation and anti-coagulation systems, but in disseminated intravascular coagulation (DIC the coagulation mechanism is activated inappropriately and in a diffuse way. This may lead to thrombosis, but more often haemorrhage occurs when the clotting factors are exhausted. DIC may present as acute, subacute, and rarely chronic form. Here we present a case of chronic DIC following pelvic inflammatory disease (PID as a consequence of repeated menstruation regulation (MR. We treated her with fresh frozen plasma, fresh blood, doxycycline with significant clinical improvement.DOI: 10.3329/bsmmuj.v1i1.3696 BSMMU J 2008; 1(1: 33-34

  4. Ventricular metastasis resulting in disseminated intravascular coagulation

    Directory of Open Access Journals (Sweden)

    Davis Ian D

    2005-05-01

    Full Text Available Abstract Background Disseminated Intravascular Coagulation (DIC complicates up to 7% of malignancies, the commonest solid organ association being adenocarcinoma. Transitional Cell Carcinoma (TCC has rarely been associated with DIC. Case presentation A 74-year-old woman with TCC bladder and DIC was found to have a cardiac lesion suspicious for metastatic disease. The DIC improved with infusion of plasma and administration of Vitamin K, however the cardiac lesion was deemed inoperable and chemotherapy inappropriate; given the patients functional status. We postulate that direct activation of the coagulation cascade by the intraventricular metastasis probably triggered the coagulopathy in this patient. Conclusion Cardiac metastases should be considered in cancer patients with otherwise unexplained DIC. This may influence treatment choices.

  5. Disseminated visceral coccidiosis in sandhill cranes

    Science.gov (United States)

    Carpenter, J.W.; Novilla, M.N.; Fayer, R.; Iverson, G.C.

    1984-01-01

    Disseminated visceral coccidiosis (DVC) caused by Eimeria spp was first recognized as a disease entity in captive sandhill cranes (Grus canadensis) and whooping cranes (G americana) at the Patuxent Wildlife Research Center. Because cranes produced at the Center are reintroduced to the wild to augment wild populations, studies involving both experimentally induced and natural infections were initiated to determine the potential or actual occurrence of DVC in wild Gruidae. Nine sandhill cranes dosed orally with eimerian oocysts of wild origin developed lesions characteristic of DVC. Extraintestinal granulomas associated with developing schizonts were found in 6 birds. Similar lesions were observed in wild sandhill cranes throughout parts of midwestern United States, Alaska, and Saskatchewan. These studies revealed the wide geographic distribution and the high frequency of occurrence of DVC in wild cranes.

  6. Acute disseminated encephalomyelitis in dengue viral infection.

    Science.gov (United States)

    Wan Sulaiman, Wan Aliaa; Inche Mat, Liyana Najwa; Hashim, Hasnur Zaman; Hoo, Fan Kee; Ching, Siew Mooi; Vasudevan, Ramachandran; Mohamed, Mohd Hazmi; Basri, Hamidon

    2017-09-01

    Dengue is the most common arboviral disease affecting many countries worldwide. An RNA virus from the flaviviridae family, dengue has four antigenically distinct serotypes (DEN-1-DEN-4). Neurological involvement in dengue can be classified into dengue encephalopathy immune-mediated syndromes, encephalitis, neuromuscular or dengue muscle dysfunction and neuro-ophthalmic involvement. Acute disseminated encephalomyelitis (ADEM) is an immune mediated acute demyelinating disorder of the central nervous system following recent infection or vaccination. This monophasic illness is characterised by multifocal white matter involvement. Many dengue studies and case reports have linked ADEM with dengue virus infection but the association is still not clear. Therefore, this article is to review and discuss concerning ADEM in dengue as an immune-medicated neurological complication; and the management strategy required based on recent literature. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Self-Adjuvanting Glycopeptide Conjugate Vaccine against Disseminated Candidiasis

    Science.gov (United States)

    Xin, Hong; Cartmell, Jonathan; Bailey, Justin J.; Dziadek, Sebastian; Bundle, David R.; Cutler, Jim E.

    2012-01-01

    Our research on pathogenesis of disseminated candidiasis led to the discovery that antibodies specific for Candida albicans cell surface β-1, 2–mannotriose [β-(Man)3] protect mice. A 14 mer peptide Fba, which derived from the N-terminal portion of the C. albicans cytosolic/cell surface protein fructose-bisphosphate aldolase, was used as the glycan carrier and resulted in a novel synthetic glycopeptide vaccine β-(Man)3-Fba. By a dendritic cell-based immunization approach, this conjugate induced protective antibody responses against both the glycan and peptide parts of the vaccine. In this report, we modified the β-(Man)3-Fba conjugate by coupling it to tetanus toxoid (TT) in order to improve immunogenicity and allow for use of an adjuvant suitable for human use. By new immunization procedures entirely compatible with human use, the modified β-(Man)3-Fba-TT was administered either alone or as a mixture made with alum or monophosphoryl lipid A (MPL) adjuvants and given to mice by a subcutaneous (s.c.) route. Mice vaccinated with or, surprisingly, without adjuvant responded well by making robust antibody responses. The immunized groups showed a high degree of protection against a lethal challenge with C. albicans as evidenced by increased survival times and reduced kidney fungal burden as compared to control groups that received only adjuvant or DPBS buffer prior to challenge. To confirm that induced antibodies were protective, sera from mice immunized against the β-(Man)3-Fba-TT conjugate transferred protection against disseminated candidiasis to naïve mice, whereas C. albicans-absorbed immune sera did not. Similar antibody responses and protection induced by the β-(Man)3-Fba-TT vaccine was observed in inbred BALB/c and outbred Swiss Webster mice. We conclude that addition of TT to the glycopeptide conjugate results in a self-adjuvanting vaccine that promotes robust antibody responses without the need for additional adjuvant, which is novel and represents a

  8. Optimal channel choice for collaborative ad-hoc dissemination

    DEFF Research Database (Denmark)

    Hu, Liang; Boudec, J-Y. L.; Vojnovic, M.

    2010-01-01

    Collaborative ad-hoc dissemination of information has been proposed as an efficient means to disseminate information among devices in a wireless ad-hoc network. Devices help in forwarding the information channels to the entire network, by disseminating the channels they subscribe to, plus others...... by a Metropolis-Hastings sampling algorithm. We also give a variant that accounts for battery level. This leads to a practical channel selection and re-selection algorithm that can be implemented without any central control....

  9. Macrophage Function in Early Dissemination and Dormancy of Breast Cancer

    Science.gov (United States)

    2015-09-01

    AWARD NUMBER: W81XWH-14-1-0365 TITLE: Macrophage Functions in Early Dissemination and Dormancy of Breast Cancer PRINCIPAL INVESTIGATOR: Nina...TITLE AND SUBTITLE 5a. CONTRACT NUMBER Macrophage Function in Early Dissemination and Dormancy of Breast Cancer 5b. GRANT NUMBER W81XWH-14-1-0365...13. SUPPLEMENTARY NOTES 14. ABSTRACT This research project focuses on the role of macrophages in early dissemination and dormancy . We hypothesized

  10. Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host

    OpenAIRE

    Sonavane, Amey Dilip; Sonawane, Pratibha Balasaheb; Chandak, Sachet Vijay; Rathi, Pravin M

    2016-01-01

    Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient.

  11. Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host

    Science.gov (United States)

    Sonawane, Pratibha Balasaheb; Chandak, Sachet Vijay; Rathi, Pravin M

    2016-01-01

    Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient. PMID:27134914

  12. Challenges of Data Dissemination Efforts Within a Community-Based Participatory Project About Persistent Racial Disparities in Excess Weight.

    Science.gov (United States)

    Garnett, Bernice R; Wendel, Josefine; Banks, Chandra; Goodridge, Ardeene; Harding, Richard; Harris, Robin; Hacker, Karen; Chomitz, Virginia R

    2015-01-01

    Despite universal environmental and policy-focused initiatives that resulted in declines in obesity among children in Cambridge, Massachusetts, disparities persist among racial/ethnic groups. In response, a community coalition formed the Healthy Eating and Living Project (HELP), to investigate and disseminate findings regarding disparities in excess weight among Cambridge Black youth (ages 6-14), with the aim of facilitating reciprocal learning and community mobilization to ultimately increase community engagement and inform prevention efforts. This paper details the theoretical framework, methods, and results of disseminating HELP findings to various sectors of the Cambridge Black/African American (Black) community. First, using a community-based participatory research (CBPR) approach, the HELP coalition analyzed existing data and conducted qualitative studies with Cambridge Black families to better understand the sociocultural and familial determinants of excess weight. We then developed presentation and print materials and used different dissemination approaches. We solicited feedback to inform the dissemination process and mobilization of obesity prevention efforts. We disseminated information through six community groups (parents, students, pastors, men's health group, community leaders, and a health coalition), email lists, and websites. Reciprocal learning among and between HELP and community members yielded data presentation challenges, as well as prevention effort ideas and barriers. Dissemination of local health data should be considered both as a strategy to increase community engagement and as an intervention to promote collective efficacy and community change. Careful attention should be dedicated to the language used when communicating racial disparities in excess weight to various community groups.

  13. Dissemination strategy for Lean thinking in health care.

    Science.gov (United States)

    Dannapfel, Petra; Poksinska, Bozena; Thomas, Kristin

    2014-01-01

    The purpose of this paper is to contribute to knowledge about dissemination strategies for Lean thinking throughout multiple healthcare organisations. The Ostergötland county council, Sweden (CCO) was chosen as a case study for an healthcare Lean-thinking dissemination strategies. Document analysis and interviews were used and results were compared with similar strategies employed by staff at the National Health Service Institute for Innovation (NHSI) and improvement in Great Britain and the Odense University Hospital in Denmark. The Lean improvement programme was introduced to tackle challenges such as an ageing society, rising care expectations and budgetary and economic constraints. It was designed as a long-term programme to create added value for patients and employee involvement. The dissemination strategy was: forming clear visions and objectives; piloting; training potential adopters; and formal dissemination. The CCO strategy was focused primarily on managers and was not meant to involve all staff until the implementation stage. Staff at the NHSI attempted to address nurses needs during dissemination, which questioned whether the CCO managers' dissemination strategy is sustainable. This paper inspires healthcare managers and decision makers who aim to disseminate Lean production in their organisations. There are many case studies describing Lean implementation in single healthcare organisations, but little is known about effective dissemination and implementation strategies in large healthcare systems. The authors, therefore, suggest activities for developing and implementing dissemination strategies in multiple healthcare organisations.

  14. On commercial media bias

    OpenAIRE

    Germano, Fabrizio

    2008-01-01

    Within the spokes model of Chen and Riordan (2007) that allows for non-localized competition among arbitrary numbers of media outlets, we quantify the effect of concentration of ownership on quality and bias of media content. A main result shows that too few commercial outlets, or better, too few separate owners of commercial outlets can lead to substantial bias in equilibrium. Increasing the number of outlets (commercial and non-commercial) tends to bring down this bias; but the strongest ef...

  15. Informal dissemination scenarios and the effectiveness of evacuation warning dissemination of households — A Simulation study

    OpenAIRE

    Nagarajan, Magesh; Shaw, Duncan; Albores, Pavel

    2010-01-01

    Timely warning of the public during large scale emergencies is essential to ensure safety and save lives. This ongoing study proposes an agent-based simulation model to simulate the warning message dissemination among the public considering both official channels and unofficial channels The proposed model was developed in NetLogo software for a hypothetical area, and requires input parameters such as effectiveness of each official source (%), estimated time to begin informing others, estimate...

  16. SOCIAL ORIENTATION MANAGEMENT OF COMMERCIAL BANKS ACTIVITY

    Directory of Open Access Journals (Sweden)

    N. G. Shpankovskaya

    2010-06-01

    Full Text Available The modern theoretical approaches to definition of essence of social activity of enterprises are analyzed. The directions of development of social activity of commercial banks are determined. The expedience of formulation of mission of commercial banks and general requirements it must meet to is grounded.

  17. Hypothesis: Disseminated Intravascular Inflammation as the Inflammatory Counterpart to Disseminated Intravascular Coagulation

    Science.gov (United States)

    Bull, Brian S.; Bull, Maureen H.

    1994-08-01

    We have identified a leukocyte activation syndrome that is occasionally associated with the transfusion of intraoperatively recovered erythrocytes. This syndrome appears to result from intravascular damage caused by leukocytes activated during the erythrocyte salvage process. We hypothesize that this syndrome is part of a larger disease grouping: disseminated intravascular inflammation (DII). DII is the analog of the coagulation disorder disseminated intravascular coagulation. In disseminated intravascular coagulation, the organ damage results from uncontrolled activation of the clotting pathway; in DII the damage is caused by leukocytes that have become activated by direct contact with bacteria or in rare instances-such as erythrocyte salvage-in the absence of bacteria and bacterial products. Recent studies of the hazards associated with intraoperative blood salvage indicate that activation of leukocytes can be achieved by exposure to activated platelets alone. If such activated leukocytes are reinfused along with the washed erythrocytes, widespread organ damage may result. The lung is the organ most severely affected by activated leukocytes. Adult respiratory distress syndrome is one outcome. It is likely that DII is a presently unrecognized pathophysiological process that complicates a variety of primary disease states and increases their lethality.

  18. Commercialization in Innovation Management

    DEFF Research Database (Denmark)

    Sløk-Madsen, Stefan Kirkegaard; Ritter, Thomas; Sornn-Friese, Henrik

    For any firm, the ultimate purpose of new product development is the commercialization of the new offerings. Despite its regular use in the product innovation and general management science literature, commercialization is only loosely defined and applied. This lack of conceptual clarity about...... definitions and interpretations of commercialization. We offer a process-oriented definition of commercialization that is theoretically founded in the capability-based view of the firm. We also outline an agenda for future theoretical development and empirical research on commercialization aimed at advancing...

  19. DISSEMINATING MULTICULTURALISM THROUGH THE TEACHING OF TRANSLATION

    Directory of Open Access Journals (Sweden)

    Arido Laksono

    2013-12-01

    Full Text Available 800x600 ABSTRACT Students are expected to change the world. Their perspectives represent the way they view the world and its phenomena. The broader knowledge they possess, the more tolerance they have in interpreting life. In the global era, students should understand the importance of having good knowledge in multiculturalism. They will involve in an inter-cultural encounter since sources of information are widely offered. The willingness to have such an open mind is required in order to develop a better place to live and work. One way to disseminate multiculturalism values is using text containing information about culture and social values. The text written in English or Bahasa Indonesia for the class designed in disseminating multiculturalism is Translation. Here, students are taught to interpret the messages conveyed and translate the information from the source language to the target language correctly. Teacher must have good and creative technique in delivering the material so that students really enjoy the class and deeply understand the topic. The teaching and learning process in Translation class, therefore, is an effective medium to achieve the expected purpose as stated above. Theory of translation will not be the one and only theory to do the translation job, but it also needs comprehensive knowledge on other social sciences. Hence, translation class will not only discuss lines of words in a paragraph, but also reciprocal discussion among the members of the class. At the end, students will have the ability to translate such information in a text correctly and to establish civic society with more open comprehension over society and its culture. Keywords: theory of translation, multiculturalism, teaching-learning process, globalization. Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0

  20. The Safety Case and the Risk-Informed Performance-Based Approach for Management of US Commercial Low Level Radioactive Waste (LLRW)

    International Nuclear Information System (INIS)

    Abu-Eid, Rateb; Esh, David; Grossman, Chrisopher

    2016-01-01

    Summary/Conclusion Safety Case & 10 CFR Part 61: • Safety Case is an integrated approach to risk assessment and risk management. • NRC staff explicitly added “the safety case” concept in the ongoing amendment of 10 CFR Part 61, at the direction of Commission. • Plain language description the safety arguments and evidence to demonstrate the overall safety of a land disposal facility were developed. • It describes all safety relevant aspects of the disposal site, the design of the facility, and the managerial control measures and regulatory controls to inform the decision whether to grant a license. • It includes the same type of information that the original 10 CFR Part 61 required to be submitted as part of a license application (i.e., 10 CFR 61.10 – 10 CFR 61.16). • The safety case will be updated over time as a new information is gained during the various phases of the facility’s development, inspection, and operation. • 10 CFR Part 61 SC is quite consistent with IAEA SSG-23 with more detailed technical analysis.

  1. A comparison of the stress corrosion cracking susceptibility of commercially pure titanium grade 4 in Ringer's solution and in distilled water: a fracture mechanics approach.

    Science.gov (United States)

    Roach, Michael D; Williamson, R Scott; Thomas, Joseph A; Griggs, Jason A; Zardiackas, Lyle D

    2014-01-01

    From the results of laboratory investigations reported in the literature, it has been suggested that stress corrosion cracking (SCC) mechanisms may contribute to early failures in titanium alloys that have elevated oxygen concentrations. However, the susceptibility of titanium alloys to SCC in physiological environments remains unclear. In this study, a fracture mechanics approach was used to examine the SCC susceptibility of CP titanium grade 4 in Ringer's solution and distilled de-ionized (DI) water, at 37°C. The study duration was 26 weeks, simulating the non-union declaration of a plated fracture. Four wedge loads were used corresponding to 86-95% of the alloy's ligament yield load. The longest cracks were measured to be 0.18 mm and 0.10 mm in Ringer's solution and DI water, respectively. SEM analysis revealed no evidence of extensive fluting and quasi-cleavage fracture features which, in literature reports, were attributed to SCC. We thus postulate that the Ringer's solution accelerated the wedge-loaded crack growth without producing the critical stresses needed to change the fracture mechanism. Regression analysis of the crack length results led to a significant best-fit relationship between crack growth velocity (independent variable) and test electrolyte, initial wedge load, and time of immersion of specimen in electrolyte (dependent variables). Copyright © 2013 Wiley Periodicals, Inc.

  2. A novel case of canine disseminated aspergillosis following mating

    OpenAIRE

    Walker, Jackson T.; Frazho, Jean K.; Randell, Susan C.

    2012-01-01

    An intact bitch with a history of mating was presented with severe lameness and a vulvar discharge. A mixed lytic, proliferative tibial lesion and open pyometra were diagnosed. Bone biopsy and uterine culture revealed disseminated aspergillosis. This is the first report of Aspergillus pyometra with dissemination following mating in the dog.

  3. A novel case of canine disseminated aspergillosis following mating.

    Science.gov (United States)

    Walker, Jackson T; Frazho, Jean K; Randell, Susan C

    2012-02-01

    An intact bitch with a history of mating was presented with severe lameness and a vulvar discharge. A mixed lytic, proliferative tibial lesion and open pyometra were diagnosed. Bone biopsy and uterine culture revealed disseminated aspergillosis. This is the first report of Aspergillus pyometra with dissemination following mating in the dog.

  4. Disseminated Fusarium infection in autologous stem cell transplant recipient

    OpenAIRE

    Avelino-Silva, Vivian Iida; Ramos, Jessica Fernandes; Leal, Fabio Eudes; Testagrossa, Leonardo; Novis, Yana Sarkis

    2015-01-01

    Disseminated infection by Fusarium is a rare, frequently lethal condition in severely immunocompromised patients, including bone marrow transplant recipients. However, autologous bone marrow transplant recipients are not expected to be at high risk to develop fusariosis. We report a rare case of lethal disseminated Fusarium infection in an autologous bone marrow transplant recipient during pre-engraftment phase.

  5. Disseminated Fusarium infection in autologous stem cell transplant recipient

    Directory of Open Access Journals (Sweden)

    Vivian Iida Avelino-Silva

    2015-01-01

    Full Text Available Disseminated infection by Fusarium is a rare, frequently lethal condition in severely immunocompromised patients, including bone marrow transplant recipients. However, autologous bone marrow transplant recipients are not expected to be at high risk to develop fusariosis. We report a rare case of lethal disseminated Fusarium infection in an autologous bone marrow transplant recipient during pre-engraftment phase.

  6. Health information dissemination for breast cancer awareness, early ...

    African Journals Online (AJOL)

    This study is to explore how information about breast cancer (BC) is disseminated to working class mothers in Lagos State. It is to investigate how information disseminated is used by the respondents to detect early this deadly disease and ascertain if they are aware of any support by organisation and the government.

  7. Report on dissemination, monitoring and research into policy repository

    DEFF Research Database (Denmark)

    Chereches, Razvan; Rus, Diana; Aro, Arja R.

    This report covers the dissemination activities of the project REPOPA months 2 to 60 (November 2011 to September 2016). This is the second major report of the dissemination work package (WP6) submitted to the European Commission (EC), which was aimed to provide the detailed results for disseminat...

  8. Case Report: Acute disseminated encephalomyelitis in two Nigerian ...

    African Journals Online (AJOL)

    We report two children from the South-western part of Nigeria with blood culture proven typhoid fever who developed encephalopathy and acute cerebellar syndrome due to acute disseminated encephalomyelitis (ADEM). In this report, we discussed the symptomatology and management of post-Salmonella disseminated ...

  9. Identifying the challenges of creating an optimal dissemination ...

    African Journals Online (AJOL)

    It is crucial that census data is disseminated in such a way that it satisfies most user needs as far as possible, to ensure that there is optimum use of the information and that maximum value for money is provided. In the past, Statistics South Africa disseminated data at the same geographic level created for data collection.

  10. Modeling news dissemination on nuclear issues

    Energy Technology Data Exchange (ETDEWEB)

    Reis Junior, Jose S.B.; Barroso, Antonio C.O.; Menezes, Mario O., E-mail: jsbrj@ime.usp.b, E-mail: barroso@ipen.b, E-mail: mario@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    Using a modified epidemiological model, the dissemination of news by media agents after the occurrence of large scale disasters was studied. A modified compartmented model was developed in a previous paper presented at INAC 2007. There it used to study to the Chernobyl's nuclear accident (1986) and the Concorde airplane crash (2000). Now the model has been applied to a larger and more diverse group of events - nuclear, non-nuclear and naturally caused disasters. To be comprehensive, old and recent events from various regions of the world were selected. A more robust news repository was used, and improved search techniques were developed to ensure that the scripts would not count false positive news. The same model was used but with improved non-linear embedded simulation optimization algorithms to generate the parameters of interest for our model. Individual parameters and some specific combination of them allow some interesting perceptions on how the nature of the accident / disaster gives rise to different profiles of growth and decay of the news. In our studies events involving nuclear causes generate news repercussion with more explosive / robust surge profiles and longer decaying tails than those of other natures. As a consequence of these differences, public opinion and policy makers are also much more sensitive to some issues than to others. The model, through its epidemiological parameters, shows in quantitative manner how 'nervous' the media content generators are with respect to nuclear installations and how resilient this negative feelings about nuclear is. (author)

  11. Modeling news dissemination on nuclear issues

    International Nuclear Information System (INIS)

    Reis Junior, Jose S.B.; Barroso, Antonio C.O.; Menezes, Mario O.

    2011-01-01

    Using a modified epidemiological model, the dissemination of news by media agents after the occurrence of large scale disasters was studied. A modified compartmented model was developed in a previous paper presented at INAC 2007. There it used to study to the Chernobyl's nuclear accident (1986) and the Concorde airplane crash (2000). Now the model has been applied to a larger and more diverse group of events - nuclear, non-nuclear and naturally caused disasters. To be comprehensive, old and recent events from various regions of the world were selected. A more robust news repository was used, and improved search techniques were developed to ensure that the scripts would not count false positive news. The same model was used but with improved non-linear embedded simulation optimization algorithms to generate the parameters of interest for our model. Individual parameters and some specific combination of them allow some interesting perceptions on how the nature of the accident / disaster gives rise to different profiles of growth and decay of the news. In our studies events involving nuclear causes generate news repercussion with more explosive / robust surge profiles and longer decaying tails than those of other natures. As a consequence of these differences, public opinion and policy makers are also much more sensitive to some issues than to others. The model, through its epidemiological parameters, shows in quantitative manner how 'nervous' the media content generators are with respect to nuclear installations and how resilient this negative feelings about nuclear is. (author)

  12. The problem of dissemination: evidence and ideology.

    Science.gov (United States)

    Traynor, M

    1999-09-01

    This paper recontextualises research evidence as an example of textually-based social control. It does this by drawing on two areas of theoretical literature; feminist literary theory and the sociology of scientific knowledge. Accounts of literary works as ideological instruments of social control suggest that (at least some kinds of) research literature may fulfil a similar role among a clinical readership. There have also been compelling accounts of scientific writing as expressions of desire on the part of one group to 'act at a distance' upon others. In the light of this literature, it becomes less tenable to see research dissemination as the simple transfer of information, supplemented by organisational work. Research is implicated in the attempt by one group to enrol others in its own project and in the (self-)construction of the identities of the healthcare worker. The accounts that literary theory can provide do not remain focused upon the text, but draw links between the reading process and the experience and place in society, for example the gender, of the writer and reader. As such their explanations create a space for the resisting reader.

  13. Acute disseminated encephalomyelitis; Akute disseminierte Enzephalomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Politi, M.; Papanagiotou, P.; Grunwald, I.Q.; Roth, C.; Reith, W. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar (Germany)

    2008-06-15

    Acute disseminated encephalomyelitis (ADEM) is an acute widespread autoimmune demyelinating condition, which principally affects the white matter of the brain and spinal cord. It usually follows an infection or vaccination. The typical presentation is that of multifocal neurologic disturbances accompanied by change in mental status. CSF analysis reveals lymphocytic pleocytosis and elevated protein content, but may also yield normal results. MRI is regarded as the diagnostic imaging modality of choice and typically demonstrates involvement of deep cerebral hemispheric and subcortical white matter as well as lesions in the basal ganglia, gray-white junction, diencephalon, brainstem, cerebellum and spinal cord. Unlike multiple sclerosis (MS), ADEM has a monophasic course and a favorable long-term prognosis. (orig.) [German] Die akute disseminierte Enzephalomyelitis (ADEM) ist eine akut auftretende autoimmune demylinisierende Erkrankung der weissen Substanz, die hauptsaechlich Gehirn und Rueckenmark befaellt. Ueblicherweise tritt sie nach einer Infektion oder Impfung auf. Die Entwicklung einer fokalen oder multifokalen neurologischen Funktionsstoerung ist das Kennzeichen der klinischen Praesentation der ADEM. Lymphozytaere Pleozytose und Eiweisserhoehung sind typische Befunde in der Liquoruntersuchung. Die Magnetresonanztomographie (MRT) ist die Untersuchungsmethode der Wahl. Die ADEM-Laesionen sind typischerweise gross, multipel und asymmetrisch. Sie koennen in den Gross- und Kleinhirnhemisphaeren, im Hirnstamm und im Rueckenmark lokalisiert sein. Die subkortikale und die zentrale weisse Substanz sind am haeufigsten befallen. Weniger haeufig ist die graue Substanz der Thalami und der Basalganglien betroffen. Im Gegensatz zur Multiplen Sklerose (MS) ist die Prognose der ADEM im Allgemeinen guenstig. (orig.)

  14. MRI findings of acute disseminated encephalomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Sei Jung; Suh, Jung Ho; Kim, Dong Ik; Chung, Tae Sub; Lee, So Jin [Yonsei University College of Medicine, Seoul (Korea, Republic of)

    1993-07-15

    Acute disseminate encephalomyelitis (ADEM) is a demyelinating disease of probable autoimmune etiology. The MR images of patients with clinically suspected ADEM were retrospectively reviewed. The clinical symptoms occurred 5 days to 1 month after viral upper respiratory infection (4) and Coxsakie viral infection (1). The symptoms had begun with fever (3), headache (3), sore throat (1), and drowsy mental state (1), which progressed with monophasic course to altered mental change (2), extremity weakness (2), seizure (1) and/or cerebellar symptom (1). MRI findings of ADEM showed patchy (4), non hemorrhagic (5), asymmetric (5) high signal intensity lesions on T2-weighted images. The number of the lesions was mostly multiple (4). The lesions mainly involved the brain stem (3) and subcortical while matter (3). Follow-up MR images of 13 days to 20 days after high dose steroid therapy showed marked improvement in two of three, which well corrected with clinical manifestations. MR finding of multiple, patchy, nonhemorrhagic and asymmetric lesions in subcortical white matter and brain stem on T2-weighted images seem to be characteristic features of ADEM, but nonspecific. Therefore, clinical correlation is required in evaluating ADEM.

  15. Vasogenic edema characterizes pediatric acute disseminated encephalomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Zuccoli, Giulio; Panigrahy, Ashok; Sreedher, Gayathri; Bailey, Ariel [Children' s Hospital of Pittsburgh of UPMC, Department of Radiology, Section of Neuroradiology, Pittsburgh, PA (United States); Laney, Ernest John [Children' s Hospital of Pittsburgh of UPMC, Department of Radiology, Section of Neuroradiology, Pittsburgh, PA (United States); Rush University Medical Center, Department of Diagnostic Radiology, Chicago, IL (United States); La Colla, Luca [University of Parma, Department of Anesthesiology, Parma (Italy); UPMC Shadyside Hospital, Department of Emergency Medicine, Pittsburgh, PA (United States); Alper, Gulay [Children' s Hospital of Pittsburgh of UPMC, Department of Pediatric Neurology, Neuroimmunology Clinic, Pittsburgh, PA (United States)

    2014-08-15

    MR imaging criteria for diagnosing acute disseminated encephalomyelitis (ADEM) have not been clearly established. Due to the wide spectrum of differential considerations, new imaging features allowing early and accurate diagnosis for ADEM are needed. We hypothesized that ADEM lesions would be characterized by vasogenic edema due to the potential reversibility of the disease. Sixteen patients who met the diagnostic criteria for ADEM proposed by the International Pediatric Multiple Sclerosis Study Group (IPMSSG) and had complete MR imaging studies performed at our institution during the acute phase of the disease were identified retrospectively and evaluated by experienced pediatric neuroradiologists. Vasogenic edema was demonstrated on diffusion-weighted imaging (DWI) and corresponding apparent diffusion coefficient (ADC) maps in 12 out of 16 patients; cytotoxic edema was identified in two patients while the other two patients displayed no changes on DWI/ADC. ADC values for lesions and normal-appearing brain tissue were 1.39 ± 0.45 x 10{sup -3} and 0.81 ± 0.09 x 10{sup -3} mm/s{sup 2}, respectively (p = 0.002). When considering a cutoff of 5 days between acute and subacute disease, no difference between ADC values in acute vs. subacute phase was depicted. However, we found a significant correlation and an inverse and significant relationship between time and ADC value. We propose that vasogenic edema is a reliable diagnostic sign of acute neuroinflammation in ADEM. (orig.)

  16. DDDRC: decentralised data dissemination in VANET using raptor codes

    Science.gov (United States)

    Kumar, Rakesh; Dave, Mayank

    2015-06-01

    The design of data dissemination protocol has been a great challenge due to the highly dynamic and unreliable wireless channel in vehicular ad hoc networks (VANET). In literature, several interesting solutions are proposed to perform data dissemination for this environment. But these solutions either use architectures requiring centralised coordination or global network knowledge or large intermediate buffers. In this paper, we propose a decentralised technique that overcomes above requirements and provides reliable and scalable communication in both dense and sparse traffic for VANET. Random walks are used in the proposed technique to disseminate data from one vehicle to other vehicles in the network. We use raptor codes to provide low decoding complexity and more scalability for data dissemination. Simulation results demonstrate that the proposed technique has better fault tolerance with lower complexity than general random-walk-based dissemination process and more scalability as compared to the other protocols.

  17. Option pricing: a flexible tool to disseminate shared savings contracts.

    Science.gov (United States)

    Friedberg, Mark W; Buendia, Anthony M; Lauderdale, Katherine E; Hussey, Peter S

    2013-08-01

    Due to volatility in healthcare costs, shared savings contracts can create systematic financial losses for payers, especially when contracting with smaller providers. To improve the business case for shared savings, we calculated the prices of financial options that payers can "sell" to providers to offset these losses. Using 2009 to 2010 member-level total cost of care data from a large commercial health plan, we calculated option prices by applying a bootstrap simulation procedure. We repeated these simulations for providers of sizes ranging from 500 to 60,000 patients and for shared savings contracts with and without key design features (minimum savings thresholds,bonus caps, cost outlier truncation, and downside risk) and under assumptions of zero, 1%, and 2% real cost reductions due to the shared savings contracts. Assuming no real cost reduction and a 50% shared savings rate, per patient option prices ranged from $225 (3.1% of overall costs) for 500-patient providers to $23 (0.3%) for 60,000-patient providers. Introducing minimum savings thresholds, bonus caps, cost outlier truncation, and downside risk reduced these option prices. Option prices were highly sensitive to the magnitude of real cost reductions. If shared savings contracts cause 2% reductions in total costs, option prices fall to zero for all but the smallest providers. Calculating the prices of financial options that protect payers and providers from downside risk can inject flexibility into shared savings contracts, extend such contracts to smaller providers, and clarify the tradeoffs between different contract designs, potentially speeding the dissemination of shared savings.

  18. Qualitative and mixed methods research in dissemination and implementation science: introduction to the special issue.

    Science.gov (United States)

    Southam-Gerow, Michael A; Dorsey, Shannon

    2014-01-01

    This special issue provides examples of how qualitative and mixed methods research approaches can be used in dissemination and implementation science. In this introductory article, we provide a brief rationale for why and how qualitative and mixed methods approaches can be useful in moving the field forward. Specifically, we provide a brief primer on common qualitative methods, including a review of guidelines provided by the National Institutes of Health. Next, we introduce the six articles in the issue. The first of the articles by Palinkas represents a more thorough and authoritative discussion related to qualitative methods, using the other five articles in the issue (and other published works) as examples. The remaining five articles are empirical and/or descriptive articles of recently completed or ongoing qualitative or mixed methods studies related to dissemination and implementation of evidence-based practices for children and adolescents.

  19. Worksite Tobacco Prevention: A Randomized, Controlled Trial of Adoption, Dissemination Strategies, and Aggregated Health-Related Outcomes across Companies.

    Science.gov (United States)

    Friedrich, Verena; Brügger, Adrian; Bauer, Georg F

    2015-01-01

    Evidence based public health requires knowledge about successful dissemination of public health measures. This study analyses (a) the changes in worksite tobacco prevention (TP) in the Canton of Zurich, Switzerland, between 2007 and 2009; (b1) the results of a multistep versus a "brochure only" dissemination strategy; (b2) the results of a monothematic versus a comprehensive dissemination strategy that aim to get companies to adopt TP measures; and (c) whether worksite TP is associated with health-related outcomes. A longitudinal design with randomized control groups was applied. Data on worksite TP and health-related outcomes were gathered by a written questionnaire (baseline n = 1627; follow-up n = 1452) and analysed using descriptive statistics, nonparametric procedures, and ordinal regression models. TP measures at worksites improved slightly between 2007 and 2009. The multistep dissemination was superior to the "brochure only" condition. No significant differences between the monothematic and the comprehensive dissemination strategies were observed. However, improvements in TP measures at worksites were associated with improvements in health-related outcomes. Although dissemination was approached at a mass scale, little change in the advocated adoption of TP measures was observed, suggesting the need for even more aggressive outreach or an acceptance that these channels do not seem to be sufficiently effective.

  20. The importance of serological tests implementation in disseminated candidiasis diagnose.

    Science.gov (United States)

    Gegić, Merima; Numanović, Fatima; Delibegović, Zineta; Tihić, Nijaz; Nurkić, Mahmut; Hukić, Mirsada

    2013-03-01

    Candidiasis is defined as an infection or disease caused by a fungus of the genus Candida. Rate of disseminated candidiasis increases with the growth of the number of immunocompromised patients. In the the last few decades the incidence of disseminated candidiasis is in growth as well as the mortality rate. The aim of this survey is to show the importance of serological tests implementation in disseminated candidiasis diagnose. This is a prospective study involving 60 patients with malign diseases with and without clinical signs of disseminated candidiasis and 30 healthy people who represent the control group. Apart from hemoculture, detection of circulating mannan antigen and adequate antibodies of Candida species applying comercial ELISA test was determined in each patient. This survey deals with relevant factors causing disseminated candidiasis. This survey showed that the group of patients with clinical signs of disseminated candidiasis had more patients with positive hemoculture to Candida species, then the group of patients without clinical signs of disseminated candidiasis. The number of patients being examined and positive to antigens and antibodies was higher (p candidiasis (7/30; 23.3%), then in the group of patients without clinical signs of disseminated candidiasis (0/30; 0%): Average value of titra antigen was statistically higher (p candidiasis 6/30 (20%) of patients had Candida spp.positive hemocultures while in the group of patients without clinical signs of disseminated candidiasis 1/30 (3.3%) of patients had Candida spp. positive hemocultures, which was considerably higher (p candidiasis were statistically significant, while correlation of results of hemoculture and antibodies was insignificant. Because of low sensitivity of hemoculture and time needed for isolation of Candida spp., introducing serological tests in regular procedures would speed disseminated candidiasis diagnose.

  1. Commercial transport aircraft composite structures

    Science.gov (United States)

    Mccarty, J. E.

    1983-01-01

    The role that analysis plays in the development, production, and substantiation of aircraft structures is discussed. The types, elements, and applications of failure that are used and needed; the current application of analysis methods to commercial aircraft advanced composite structures, along with a projection of future needs; and some personal thoughts on analysis development goals and the elements of an approach to analysis development are discussed.

  2. Problems of intangible assets commercialization accounting

    Directory of Open Access Journals (Sweden)

    S.F. Legenchyk

    2016-03-01

    Full Text Available The growing role of intangible assets in conditions of global economy postindustrialization is grounded. The problems of intangible assets accounting are singled out. The basic tasks of the intangible assets accounting commercialization process are determined. The difference between the commercialization of intellectual property and intangible assets is considered. The basic approaches to understanding the essence of the intangible assets commercialization are singled out and grounded. The basic forms and methods of intangible assets commercialization researched by the author are analyzed. The order of accounting reflection of licensee royalties is considered. The factors of influence on the accounting process of intangible assets commercialization are determined. The necessity of solving the problem of accounting of lease payments for computer program by providing access to SaaS environment is grounded. The prospects of further studies of intangible assets accounting commercialization are determined.

  3. Successful Treatment of Refractory Hypoxemia Secondary to Disseminated Histoplasmosis Using Extracorporeal Membrane Oxygenation Support.

    Science.gov (United States)

    Wanta, Brendan T; Tyner, Harmony L; Bohman, John K; Baddour, Larry M

    2016-10-15

    Refractory hypoxemia secondary to acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membraneoxygenation (ECMO) is an accepted strategy for treating refractory hypoxemia in patients with ARDS but is relatively contraindicated in the setting of systemic infections. We present a case of successful ECMO use in a host with refractory hypoxemia secondary to disseminated histoplasmosis with fungemia and discuss our management approach to this difficult patient.

  4. Commercial technologies from the SP-100 program

    International Nuclear Information System (INIS)

    Truscello, V.C.; Fujita, T.; Mondt, J.F.

    1995-01-01

    For more than a decade, Jet Propulsion Labortory and Los Alamos have managed a multi-agency funded effort to develop a space reactor power system. This SP-100 Program has developed technologies required for space power systems that can be implemented in the industrial and commercial sectors to improve competitiveness in the global economy. Initial steps taken to transfer this technology from the laboratories to industrial and commercial entities within United States include: (1) identifying specific technologies having commercial potential; (2) distributing information describing the identified technologies and interacting with interested commercial and industrial entities to develop application-specific details and requirements; and (3) providing a technological data base that leads to transfer of technology or the forming of teaming arrangements to accomplish the transfer by tailoring the technology to meet application-specific requirements. SP-100 technologies having commercial potential encompass fabrication processes, devices, and components. Examples: a process for bonding refractory metals to graphite, a device to sense the position of an actuator and a component to enable rotating machines to operate without supplying lubrication (self-lubricating ball bearing). Shortly after the NASA Regional Technology Transfer Centers widely disseminated information covering SP-100 technologies, over one hundred expressions of interest were received, which indicate that there is a large potential benefit in transferring SP-100 technology. Interactions with industrial and commercial entities have identified a substantial need for creating teaming arrangements involving the interested entity and personnel from laboratories and their contractors, who have the knowledge and ability to tailor the technology to meet application-specific requirements. copyright 1995 American Institute of Physics

  5. Fatal disseminated toxoplasmosis in an immunocompetent cat

    Directory of Open Access Journals (Sweden)

    Susanna S. Nagel

    2013-02-01

    Full Text Available A 10-year-old domestic short hair cat was referred for investigation of anorexia and polydipsia of 3 days’ duration. Clinically the cat was obese, pyrexic (39.8 °C, had acute abdominal pain and severe bilirubinuria. Haematology and serum biochemistry revealed severe panleukopenia, thrombocytopenia, markedly elevated alanine aminotransferase (ALT and five-fold increased pre-prandial bile acids. Ultrasonographic evaluation of the abdomen did not identify any abnormalities. Serum tests for feline immunodeficiency virus (FIV and feline leukaemia virus (FeLV were negative. Broad-spectrum antibiotic treatment for infectious hepatitis was to no avail; the cat deteriorated and died 72 h after admission. Necropsy revealed mild icterus and anaemia, severe multifocal hepatic necrosis, serofibrinous hydrothorax, pulmonary oedema and interstitial pneumonia. Histopathology confirmed the macroscopic findings and revealed multifocal microgranulomata in the brain and myocardium, as well as areas of necrosis in lymph nodes and multifocally in splenic red pulp. Long bone shaft marrow was hyperplastic with a predominance of leukocyte precursors and megakaryocytes and splenic red pulp showed mild extramedullary haemopoiesis. Immunohistochemical staining for Toxoplasma gondii was strongly positive, with scattered cysts and tachyzoites in the liver, lymph nodes, spleen, lungs, brain, salivary glands and intracellularly in round cells in occasional blood vessels. Immunohistochemical staining for corona virus on the same tissues was negative, ruling out feline infectious peritonitis (FIP. Polymerase chain reaction (PCR on formalin-fixed paraffin-wax embedded tissues was positive for Toxoplasma sp., but attempts at sequencing were unsuccessful. This was the first case report of fulminant disseminated toxoplasmosis in South Africa, in which detailed histopathology in an apparently immunocompetent cat was described.

  6. Bacterial Dissemination to the Brain in Sepsis.

    Science.gov (United States)

    Singer, Benjamin H; Dickson, Robert P; Denstaedt, Scott J; Newstead, Michael W; Kim, Kwi; Falkowski, Nicole R; Erb-Downward, John R; Schmidt, Thomas M; Huffnagle, Gary B; Standiford, Theodore J

    2018-03-15

    Sepsis causes brain dysfunction and neuroinflammation. It is unknown whether neuroinflammation in sepsis is initiated by dissemination of bacteria to the brain and sustained by persistent infection, or whether neuroinflammation is a sterile process resulting solely from circulating inflammatory mediators. To determine if gut bacteria translocate to the brain during sepsis, and are associated with neuroinflammation. Murine sepsis was induced using cecal ligation and puncture, and sepsis survivor mice were compared with sham and unoperated control animals. Brain tissue of patients who died of sepsis was compared with patients who died of noninfectious causes. Bacterial taxa were characterized by 16S ribosomal RNA gene sequencing in both murine and human brain specimens; compared among sepsis and nonsepsis groups; and correlated with levels of S100A8, a marker of neuroinflammation using permutational multivariate ANOVA. Viable gut-associated bacteria were enriched in the brains of mice 5 days after surviving abdominal sepsis (P < 0.01), and undetectable by 14 days. The community structure of brain-associated bacteria correlated with severity of neuroinflammation (P < 0.001). Furthermore, bacterial taxa detected in brains of humans who die of sepsis were distinct from those who died of noninfectious causes (P < 0.001) and correlated with S100A8/A9 expression (P < 0.05). Although bacterial translocation is associated with acute neuroinflammation in murine sepsis, bacterial translocation did not result in chronic cerebral infection. Postmortem analysis of patients who die of sepsis suggests a role for bacteria in acute brain dysfunction in sepsis. Further work is needed to determine if modifying gut-associated bacterial communities modulates brain dysfunction after sepsis.

  7. Commercial imagery archive, management, exploitation, and distribution product development

    Science.gov (United States)

    Hollinger, Bruce; Sakkas, Alysa

    1999-12-01

    The Lockheed Martin (LM) team had garnered over a decade of operational experience on the U.S. Government's IDEX II (Imagery Dissemination and Exploitation) system. Recently, it set out to create a new commercial product to serve the needs of large-scale imagery archiving and analysis markets worldwide. LM decided to provide a turnkey commercial solution to receive, store, retrieve, process, analyze and disseminate in 'push' or 'pull' modes imagery, data and data products using a variety of sources and formats. LM selected 'best of breed' hardware and software components and adapted and developed its own algorithms to provide added functionality not commercially available elsewhere. The resultant product, Intelligent Library System (ILS)TM, satisfies requirements for (a) a potentially unbounded, data archive (5000 TB range) (b) automated workflow management for increased user productivity; (c) automatic tracking and management of files stored on shelves; (d) ability to ingest, process and disseminate data volumes with bandwidths ranging up to multi- gigabit per second; (e) access through a thin client-to-server network environment; (f) multiple interactive users needing retrieval of files in seconds from both archived images or in real time, and (g) scalability that maintains information throughput performance as the size of the digital library grows.

  8. Commercial imagery archive, management, exploitation, and distribution project development

    Science.gov (United States)

    Hollinger, Bruce; Sakkas, Alysa

    1999-10-01

    The Lockheed Martin (LM) team had garnered over a decade of operational experience on the U.S. Government's IDEX II (Imagery Dissemination and Exploitation) system. Recently, it set out to create a new commercial product to serve the needs of large-scale imagery archiving and analysis markets worldwide. LM decided to provide a turnkey commercial solution to receive, store, retrieve, process, analyze and disseminate in 'push' or 'pull' modes imagery, data and data products using a variety of sources and formats. LM selected 'best of breed' hardware and software components and adapted and developed its own algorithms to provide added functionality not commercially available elsewhere. The resultant product, Intelligent Library System (ILS)TM, satisfies requirements for (1) a potentially unbounded, data archive (5000 TB range) (2) automated workflow management for increased user productivity; (3) automatic tracking and management of files stored on shelves; (4) ability to ingest, process and disseminate data volumes with bandwidths ranging up to multi- gigabit per second; (5) access through a thin client-to-server network environment; (6) multiple interactive users needing retrieval of files in seconds from both archived images or in real time, and (7) scalability that maintains information throughput performance as the size of the digital library grows.

  9. Breathing clean air is Są’áh Naagháí Bik'eh Hózhóó (SNBH): a culturally centred approach to understanding commercial smoke-free policy among the Diné (Navajo People)

    Science.gov (United States)

    Chief, Carmenlita; Sabo, Samantha; Clark, Hershel; Nez Henderson, Patricia; Yazzie, Alfred; Nahee, Jacqueline; Leischow, Scott J

    2016-01-01

    Introduction Indigenous worldviews and research approaches are fundamental to make meaning of complex health issues and increase the likelihood of identifying existing cultural protective factors that have contributed to the resilience and survival of Indigenous people worldwide. Objective We describe the process for applying the Diné (Navajo) paradigm of Są’áh Naagháí Bik'eh Hózhóó (SNBH), a belief system that guides harmonious living, and demonstrate how the application of SNBH enhances understanding of Navajo principles for well-being. Specifically, we juxtapose this analysis with a conventional qualitative analysis to illuminate and interpret Diné perspectives on the health and economic impact of commercial secondhand smoke and smoke-free policy. Methods Focus groups were conducted throughout Navajo Nation to assess the appeal and impact of several evidence-based messages regarding the health and economic impact of smoke-free policy. Results Diné perspectives have shifted away from family and cultural teachings considered protective of a smoke-free life, and struggle to balance the ethical and economics of respect for individual and collective rights to live and work in smoke-free environments. Conclusions Indigenous-centred approaches to public health research and policy analysis contribute to understanding the cultural knowledge, practices and beliefs that are protective of the health and well-being of Indigenous people. PMID:27697944

  10. Cacades: A reliable dissemination protocol for data collection sensor network

    Science.gov (United States)

    Peng, Y.; Song, W.; Huang, R.; Xu, M.; Shirazi, B.; LaHusen, R.; Pei, G.

    2009-01-01

    In this paper, we propose a fast and reliable data dissemination protocol Cascades to disseminate data from the sink(base station) to all or a subset of nodes in a data collection sensor network. Cascades makes use of the parentmonitor-children analogy to ensure reliable dissemination. Each node monitors whether or not its children have received the broadcast messages through snooping children's rebroadcasts or waiting for explicit ACKs. If a node detects a gap in its message sequences, it can fetch the missing messages from its neighbours reactively. Cascades also considers many practical issues for field deployment, such as dynamic topology, link/node failure, etc.. It therefore guarantees that a disseminated message from the sink will reach all intended receivers and the dissemination is terminated in a short time period. Notice that, all existing dissemination protocols either do not guarantee reliability or do not terminate [1, 2], which does not meet the requirement of real-time command control. We conducted experiment evaluations in both TOSSIM simulator and a sensor network testbed to compare Cascades with those existing dissemination protocols in TinyOS sensor networks, which show that Cascades achieves a higher degree of reliability, lower communication cost, and less delivery delay. ??2009 IEEE.

  11. Strategies for Disseminating Qualitative Research Findings: Three Exemplars

    Directory of Open Access Journals (Sweden)

    Steven Keen

    2007-09-01

    Full Text Available Assuming there are those who do pay attention to the dissemination of qualitative research findings, what can we learn from them? For this article, we searched for examples of qualitative research where findings have been disseminated beyond the journal article and/or conference presentation. The rationale for pursuing examples of how good qualitative research has been disseminated is that we pay attention to both scientific and communicative concerns. All three exemplars in this article go beyond the forms of dissemination that traditionally serve academic communities and attempt to address the communicative concern of qualitative research findings. This is not to say that these modes of dissemination replace the scholarship of qualitative research and/or the peer-reviewed journal manuscript—far from it. In disseminating qualitative data, researchers have an array of presentational styles and formats to choose from that best fit their research purposes, such as drama, dance, poetry, websites, video and evocative forms of writing. We conclude by considering the ethical issues that may be involved in these forms of disseminating qualitative research, as well as the challenges for evaluating the impact of such strategies. URN: urn:nbn:de:0114-fqs0703174

  12. REPAiR: REsource Management in Peri-urban AReas: Going Beyond Urban Metabolism : D 8.6 Detailed Dissemination Plan and Dissemination Kit

    NARCIS (Netherlands)

    Cerić, Dennis; Amenta, L.; Attademo, Anna

    2017-01-01

    The Detailed Dissemination Plan and Dissemination Kit is a strategic document for the beneficiaries helping them to establish the bases for their dissemination activities. It is a more detailed version of the Basic Dissemination Plan and Corporate Identity, deliverables of the REPAiR project D 8.3

  13. Commercialism in Intercollegiate Athletics.

    Science.gov (United States)

    Delany, James E.

    1997-01-01

    Outlines the history of intercollegiate athletics and the evolution of commercialization in college sports, particularly through television. Argues that few Division I programs could be self-sufficient; the issue is the degree to which sports are commercialized for revenue, and the challenge to balance schools' needs, private sector interests, and…

  14. Migration to Earth Observation Satellite Product Dissemination System at JAXA

    Science.gov (United States)

    Ikehata, Y.; Matsunaga, M.

    2017-12-01

    JAXA released "G-Portal" as a portal web site for search and deliver data of Earth observation satellites in February 2013. G-Portal handles ten satellites data; GPM, TRMM, Aqua, ADEOS-II, ALOS (search only), ALOS-2 (search only), MOS-1, MOS-1b, ERS-1 and JERS-1 and archives 5.17 million products and 14 million catalogues in total. Users can search those products/catalogues in GUI web search and catalogue interface(CSW/Opensearch). In this fiscal year, we will replace this to "Next G-Portal" and has been doing integration, test and migrations. New G-Portal will treat data of satellites planned to be launched in the future in addition to those handled by G - Portal. At system architecture perspective, G-Portal adopted "cluster system" for its redundancy, so we must replace the servers into those with higher specifications when we improve its performance ("scale up approach"). This requests a lot of cost in every improvement. To avoid this, Next G-Portal adopts "scale out" system: load balancing interfaces, distributed file system, distributed data bases. (We reported in AGU fall meeting 2015(IN23D-1748).) At customer usability perspective, G-Portal provides complicated interface: "step by step" web design, randomly generated URLs, sftp (needs anomaly tcp port). Customers complained about the interfaces and the support team had been tired from answering them. To solve this problem, Next G-Portal adopts simple interfaces: "1 page" web design, RESTful URL, and Normal FTP. (We reported in AGU fall meeting 2016(IN23B-1778).) Furthermore, Next G-Portal must merge GCOM-W data dissemination system to be terminated in the next March as well as the current G-Portal. This might arrise some difficulties, since the current G-Portal and GCOM-W data dissemination systems are quite different from Next G-Portal. The presentation reports the knowledge obtained from the process of merging those systems.

  15. Telemedicine: challenges to dissemination in Brazil.

    Science.gov (United States)

    Maldonado, Jose Manuel Santos de Varge; Marques, Alexandre Barbosa; Cruz, Antonio

    2016-11-03

    Telemedicine has been seen as an important tool for facing the challenges of universal health systems. The goal of this article is to discuss the main challenges to its full dissemination in Brazil. Being a somewhat new area, there are not many scientific papers that systematize it. This article is an exploratory paper, as it aims to provide an overall perspective on the subject. From an economic point of view, telemedicine is a strategic area due to its an intrinsic potential of being a source for generating innovation, for requiring and incorporating technological breakthroughs from other areas, and for its interdisciplinary nature and dynamic inter-relations that drive different industries. From the social perspective, it has the potential to make access to health services democratic, by connecting remote regions with health services located in hospitals and centers of reference for prevention, diagnosis and treatment. Resumo: A telemedicina está sendo vista como uma ferramenta importante para enfrentar os desafios dos sistemas de saúde universais. O objetivo deste artigo foi discutir os principais desafios para a sua plena disseminação no Brasil. Em função do caráter relativamente emergente desta área, existe uma escassez relativa de trabalhos científicos que a sistematizem. Por isso, este artigo se enquadra na categoria de trabalho exploratório, já que tem por objetivo proporcionar uma visão geral sobre o tema. Destaca-se, que do ponto de vista econômico, a telemedicina se constitui em uma área estratégica por seu potencial intrínseco de ser fonte geradora de inovações, por demandar e incorporar avanços tecnológicos oriundos de outras áreas e, em função da sua natureza interdisciplinar e de suas inter-relações dinâmicas, pela possibilidade de impulsionar diferentes indústrias. Do ponto de vista social, tem o potencial de democratizar o acesso aos serviços de saúde, integrando regiões remotas com serviços de saúde localizados em

  16. Technology Transfer and Commercialization

    Science.gov (United States)

    Martin, Katherine; Chapman, Diane; Giffith, Melanie; Molnar, Darwin

    2001-01-01

    During concurrent sessions for Materials and Structures for High Performance and Emissions Reduction, the UEET Intellectual Property Officer and the Technology Commercialization Specialist will discuss the UEET Technology Transfer and Commercialization goals and efforts. This will include a review of the Technology Commercialization Plan for UEET and what UEET personnel are asked to do to further the goals of the Plan. The major goal of the Plan is to define methods for how UEET assets can best be infused into industry. The National Technology Transfer Center will conduct a summary of its efforts in assessing UEET technologies in the areas of materials and emissions reduction for commercial potential. NTTC is assisting us in completing an inventory and prioritization by commercialization potential. This will result in increased exposure of UEET capabilities to the private sector. The session will include audience solicitation of additional commercializable technologies.

  17. Non-commercial vs. commercial clinical trials: a retrospective study of the applications submitted to a research ethics committee.

    Science.gov (United States)

    Fuentes Camps, Inmaculada; Rodríguez, Alexis; Agustí, Antonia

    2018-02-15

    There are many difficulties in undertaking independent clinical research without support from the pharmaceutical industry. In this retrospective observational study, some design characteristics, the clinical trial public register and the publication rate of noncommercial clinical trials were compared to those of commercial clinical trials. A total of 809 applications of drug-evaluation clinical trials were submitted from May 2004 to May 2009 to the research ethics committee of a tertiary hospital, and 16.3% of trials were noncommercial. They were mainly phase IV, multicentre national, and unmasked controlled trials, compared to the commercial trials that were mainly phase II or III, multicentre international, and double-blind masked trials. The commercial trials were registered and published more often than noncommercial trials. More funding for noncommercial research is still needed. The results of the research, commercial or noncommercial, should be disseminated in order not to compromise either its scientific or its social value. © 2018 The British Pharmacological Society.

  18. Disseminated Infection with a New Genovar of Encephalitozoon cuniculi in a Renal Transplant Recipient

    NARCIS (Netherlands)

    Talabani, Hana; Sarfati, Claudine; Pillebout, Evangeline; van Gool, Tom; Derouin, Francis; Menotti, Jean

    2010-01-01

    Disseminated microsporidiosis is a life-threatening opportunistic infection. Here, we report about a previously undescribed genovar of Encephalitozoon cuniculi causing disseminated infection in a non-HIV-infected renal transplant recipient. Disseminated microsporidiosis must be considered in the

  19. The language factor in the media and information disseminating ...

    African Journals Online (AJOL)

    MDGs) in Africa, it is observed that the language factor in media and information disseminating organisations has not been accorded the same attention as matters like speed, volume and channels of communication. Media and information ...

  20. Multi-Scale Dissemination of Time Series Data

    DEFF Research Database (Denmark)

    Guo, Qingsong; Zhou, Yongluan; Su, Li

    2013-01-01

    In this paper, we consider the problem of continuous dissemination of time series data, such as sensor measurements, to a large number of subscribers. These subscribers fall into multiple subscription levels, where each subscription level is specified by the bandwidth constraint of a subscriber......, which is an abstract indicator for both the physical limits and the amount of data that the subscriber would like to handle. To handle this problem, we propose a system framework for multi-scale time series data dissemination that employs a typical tree-based dissemination network and existing time...... to optimize the average accuracies of the data received by all subscribers within the dissemination network. Finally, we have conducted extensive experiments to study the performance of the algorithms....

  1. Chordoma with postoperative subcutaneous implantation and meningeal dissemination: MRI

    International Nuclear Information System (INIS)

    Kinoshita, T.; Okudera, T.; Shimosegawa, E.; Hatazawa, J.; Yoshida, Y.; Yasui, N.; Ogawa, T.

    2001-01-01

    Chordomas are histologically benign tumours which are locally invasive. We present an unusual case of recurrent chordoma with subcutaneous implantation and widespread meningeal dissemination after surgery. Contrast-enhanced MRI was useful for determining the extent of the tumour. (orig.)

  2. Dissemination of an Electronic Manual to Build Capacity for Implementing Farmers’ Markets with Community Health Centers

    Science.gov (United States)

    Guest, M. Aaron; Alia, Kassandra A.; Brandt, Heather M.; Friedman, Daniela B.

    2015-01-01

    Abstract Community–university partnerships can lend themselves to the development of tools that encourage and promote future community health development. The electronic manual, “Building Farmacies,” describes an approach for developing capacity and sustaining a community health center–based farmers’ market that emerged through a community–university partnership. Manual development was guided by the Knowledge to Action Framework and experiences developing a multivendor, produce‐only farmers’ market at a community health center in rural South Carolina. The manual was created to illustrate an innovative solution for community health development. The manual was disseminated electronically through 25 listservs and interested individuals voluntarily completed a Web‐based survey to access the free manual. During the 6‐month dissemination period, 271 individuals downloaded the manual. Findings highlighted the value of translating community‐based participatory research into user‐friendly manuals to guide future intervention development and dissemination approaches, and demonstrate the need to include capacity building opportunities to support translation and adoption of interventions. PMID:26296392

  3. Laparoscopic Dissection of Extensive Secondary Disseminated Peritoneal Leiomyomatosis.

    Science.gov (United States)

    Mairaing, Karicha; Huang, Kuan-Gen

    2017-10-12

    To demonstrate a minimal invasive surgical (MIS) technique for curative excision of extensive secondary disseminated peritoneal leiomyomatosis (DPL). The Institutional Review Board of Human Investigation and Ethics Committee of Chang Gung Medical Foundation ruled that approval was not required for this study. Woman aged 46 years. In MIS the myoma has to be divided into small fragments for piecemeal retrieval through a small incision [1] with a widely used technique called morcellation (confined or unconfined) [2]. DPL is a rare sequellae after laparoscopic morcellation. Because this entity is rarely reported, this video demonstrates laparoscopic technique for safe removal of DPL post laparoscopic myomectomy and morcellation. A 46-year-old woman with a past history of laparoscopic myomectomy with specimen retrieval by a power morcellation 8 years ago presented with abdominal discomfort. Computed tomography revealed multiple iso-dense lesions in the uterine corpus and pelvic cavity. Upon laparoscopy multiple nodules were identified at the previous myomectomy scar, pelvic peritoneum, ovarian surface, and over the small bowel. A total laparoscopic hysterectomy with bilateral salpingo-oophorectomy along with excision of all visible lesions was performed. In this video we demonstrate a safe retroperitoneal approach for complete excision of DPL. Laparoscopic hysterectomy or myomectomy with unconfined morcellation appears to be associated with the risk of DPL [3]. Complete tissue fragment retrieval will minimize the sequelae of morcellation. Hence, myoma remnants should be carefully extracted and confined morcellation should be considered. Because DPL causes significant distortion of pelvic anatomy, thorough knowledge of pelvic surgical anatomy and retroperitoneal approach for complete excision of all lesions is recommended. Copyright © 2017 American Association of Gynecologic Laparoscopists. Published by Elsevier Inc. All rights reserved.

  4. Disseminated paracoccidioidomycosis with peripleuritis in an AIDS patient

    OpenAIRE

    Corti,Marcelo; Villafañe,María F.; Negroni,Ricardo; Palmieri,Omar

    2004-01-01

    Paracoccidioidomycosis is one of the most frequent systemic and endemic mycoses of Latin America caused by a dimorphic fungus. In AIDS patients, paracoccidioidomycosis appears as a severe and disseminated disease with a wide spectrum of clinical findings. The CD4 counts are usually less than 200 cell/mu L. We present a case of disseminated paracoccidioidomycosis with peripleuritis and subcutaneous abscesses on the chest wall as initial manifestation of AIDS. In endemic countries, paracoccidio...

  5. Disseminated histoplasmosis in a Danish patient with AIDS

    DEFF Research Database (Denmark)

    Smith, E; Franzmann, M; Mathiesen, Lars Reinhardt

    1989-01-01

    We present the first case of disseminated histoplasmosis in an AIDS patient in Europe, a 33-year-old Danish homosexual man, and recommend a detailed travel history in HIV-positive patients presenting with fever, weight loss and organomegaly. In Scandinavia disseminated histoplasmosis is rare...... but should be kept in mind as the disease is a major opportunistic infection in patients with AIDS. Treatment with amphotericin B followed by fluconazole was effective....

  6. Acute disseminated toxoplasmosis in a juvenile cheetah (Acinonyx jubatus).

    Science.gov (United States)

    Lloyd, Christopher; Stidworthy, Mark F

    2007-09-01

    A juvenile cheetah (Acinonyx jubatus) died with rapidly progressive pyrexia, tachypnea, abdominal effusion, and hepatomegaly. Postmortem examination revealed lesions consistent with acute disseminated infection with Toxoplasma gondii. The presence of this organism was confirmed in multiple organs by immunohistochemistry and polymerase chain reaction. To the best of our knowledge, we propose this to be the first reported case of primary acute disseminated toxoplasmosis in a cheetah.

  7. SEED: a tool for disseminating systematic review data into Wikipedia.

    Science.gov (United States)

    Schmidt, Lena; Friedel, Johannes; Adams, Clive E

    2017-10-17

    Wikipedia, the free-content online encyclopaedia, contains many heavily accessed pages relating to healthcare. Cochrane systematic reviews contain much high-grade evidence but dissemination into Wikipedia has been slow. New skills are needed to both translate and relocate data from Cochrane reviews to implant into Wikipedia pages. This letter introduces a programme to greatly simplify the process of disseminating the summary of findings of Cochrane reviews into Wikipedia pages.

  8. Disseminated histoplasmosis in a Bengal tiger (Panthera tigris).

    Science.gov (United States)

    Keller, Dominique L; Steinberg, Howard; Sladky, Kurt K

    2011-12-01

    Disseminated infection with Histoplasma capsulatum was diagnosed in a 7-yr-old female Bengal tiger (Panthera tigris). Clinical signs were nonspecific with the exception of brief periods of tachypnea for 5 days prior to death. H. capsulatum organisms were found in the lungs, tracheobronchial lymph nodes, and liver. Diagnosis was confirmed by tracheal wash, urine H. capsulatum enzyme immunoassay, and necropsy results. This report represents the first published account of disseminated histoplasmosis in a tiger.

  9. Disseminated BCG infection in a patient with severe combined immunodeficiency

    International Nuclear Information System (INIS)

    Han, Tae Il; Kim, In One; Kim, Woo Sun; Yeon, Kyung Mo

    2000-01-01

    Disseminated mycobacterial infection after bacillus Calmette-Guerin (BCG) accination is a very rare disorder, occurring mostly in patients with immunologic eficiency. We report a case of disseminated BCG infection in a 16-month-old girl with severe combined immunodeficiency. Plain radiographs showed multiple osteolytic lesions in the femora, tibiae, humerus, and phalanges. Abdominal sonography and CT scanning revealed multiple nodules in the spleen, and portocaval lymphadenopathy

  10. Disseminated BCG infection in a patient with severe combined immunodeficiency

    Energy Technology Data Exchange (ETDEWEB)

    Han, Tae Il [Eulji University School of Medicine, Taejon (Korea, Republic of); Kim, In One; Kim, Woo Sun; Yeon, Kyung Mo [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2000-06-01

    Disseminated mycobacterial infection after bacillus Calmette-Guerin (BCG) accination is a very rare disorder, occurring mostly in patients with immunologic eficiency. We report a case of disseminated BCG infection in a 16-month-old girl with severe combined immunodeficiency. Plain radiographs showed multiple osteolytic lesions in the femora, tibiae, humerus, and phalanges. Abdominal sonography and CT scanning revealed multiple nodules in the spleen, and portocaval lymphadenopathy.

  11. Towards successful Dissemination of Psychological First Aid: a study of provider training preferences.

    Science.gov (United States)

    Hambrick, Erin P; Rubens, Sonia L; Vernberg, Eric M; Jacobs, Anne K; Kanine, Rebecca M

    2014-04-01

    Dissemination of Psychological First Aid (PFA) is challenging considering the complex nature of disaster response and the various disaster mental health (DMH) trainings available. To understand challenges to dissemination in community mental health centers (CMHCs), interviews were conducted with nine DMH providers associated with CMHCs. Consensual qualitative analysis was used to analyze data. Interviews were targeted toward understanding organizational infrastructure, DMH training requirements, and training needs. Results clarified challenges to DMH training in CMHCs and factors that may promote buy-in for trainings. For example, resources are limited and thus allocated for state and federal training requirements. Therefore, including PFA in these requirements could promote adoption. Additionally, a variety of training approaches that differ in content, style, and length would be useful. To conclude, a conceptual model for ways to promote buy-in for the PFA Guide is proposed.

  12. Context-Aware Multicast Protocol for Emergency Message Dissemination in Vehicular Networks

    Directory of Open Access Journals (Sweden)

    Alvin Sebastian

    2012-01-01

    emergency messages may be sent to a large number of vehicles in the area and can be propagated to only one direction. This paper presents a more efficient context-aware multicast protocol that disseminates messages only to endangered vehicles that may be affected by the emergency event. The endangered vehicles can be identified by calculating the interaction among vehicles based on their motion properties. To ensure fast delivery, the dissemination follows a routing path obtained by computing a minimum delay tree. The multicast protocol uses a generalized approach that can support any arbitrary road topology. The performance of the multicast protocol is compared with existing broadcast protocols by simulating chain collision accidents on a typical highway. Simulation results show that the multicast protocol outperforms the other protocols in terms of reliability, efficiency, and latency.

  13. [Clinical comparative analysis for pulmonary histoplasmosis and progressive disseminated histoplasmosis].

    Science.gov (United States)

    Zhang, Yan; Su, Xiaoli; Li, Yuanyuan; He, Ruoxi; Hu, Chengping; Pan, Pinhua

    2016-12-28

    To compare clinical features, diagnosis and therapeutic effect between pulmonary histoplasmosis and progressive disseminated histoplasmosis.
 Methods: A retrospective analysis for 12 cases of hospitalized patients with histoplasmosis, who was admitted in Xiangya Hospital, Central South University during the time from February 2009 to October 2015, was carried out. Four cases of pulmonary histoplasmosis and 8 cases of progressive disseminated histoplasmosis were included. The differences of clinical features, imaging tests, means for diagnosis and prognosis were analyzed between the two types of histoplasmosis.
 Results: The clinical manifestations of pulmonary histoplasmosis were mild, such as dry cough. However, the main clinical symptoms of progressive disseminated histoplasmosis were severe, including recurrence of high fever, superficial lymph node enlargement over the whole body, hepatosplenomegaly, accompanied by cough, abdominal pain, joint pain, skin changes, etc.Laboratory examination showed pancytopenia, abnormal liver function and abnormal coagulation function. One pulmonary case received the operation of left lower lung lobectomy, 3 cases of pulmonary histoplasmosis and 6 cases of progressive disseminated histoplasmosis patients were given deoxycholate amphotericin B, itraconazole, voriconazole or fluconazole for antifungal therapy. One disseminated case discharged from the hospital without treatment after diagnosis of histoplasmosis, and 1 disseminated case combined with severe pneumonia and active tuberculosis died ultimately.
 Conclusion: As a rare fungal infection, histoplasmosis is easily to be misdiagnosed. The diagnostic criteria depends on etiology through bone marrow smear and tissues biopsy. Liposomeal amphotericin B, deoxycholate amphotericin B and itraconazole are recommended to treat infection for histoplasma capsulatum.

  14. Recycling Sounds in Commercials

    DEFF Research Database (Denmark)

    Larsen, Charlotte Rørdam

    2012-01-01

    remained the same for 70 years. Together these identifiers make OMA an interesting Danish case to study. With reference to Ann Rigney’s memorial practices or mechanisms, the study aims to demonstrate how the auditory aspects of Danish margarine commercials for frying tend to be limited in variety......Commercials offer the opportunity for intergenerational memory and impinge on cultural memory. TV commercials for foodstuffs often make reference to past times as a way of authenticating products. This is frequently achieved using visual cues, but in this paper I would like to demonstrate how...

  15. A Comparison of Military and Commercial Aircraft Development

    Science.gov (United States)

    1993-04-01

    research paper examines both commercial and military approaches to aircraft development. The paper focuses on establishing whether or not commercial...challenge for design and testing. This research paper concludes that without similar mission requirements, there are few commercial applications that can be applied to military aircraft development.

  16. Nuove strategie di disseminazione e figure emergenti: gli innovation brokers + Beyond dissemination of research findings: innovation brokers as emerging figures in stimulating agricultural innovation

    NARCIS (Netherlands)

    Klerkx, L.W.A.

    2012-01-01

    More and more it is recognised that innovation cannot be explained by a linear approach to innovation in which public sector agricultural research and extension delivers new technology in a pipeline configuration through a dissemination approach, but calls for systems approach in which innovation is

  17. OPERATIONAL RISK DISCLOSURE IN ROMANIAN COMMERCIAL BANKS

    Directory of Open Access Journals (Sweden)

    HERGHILIGIU Roxana

    2013-12-01

    Full Text Available This paper aims to assess the actual operational risk disclosure in Romanian banks. Therefore we focus on the operational risk information that Romanian banks reveal and if they conform to the requirements of the National Bank of Romania. The study methodology consists in testing the annual financial reports for Romanian commercial banks. The analysis shows that the financial reports of Romanian banks are not in consonance with the requirements of the National Bank of Romania relating to operational risk revealer and also there are many discrepancies between Romanian banks relating to the format of the financial report, which presents the operational risk disclosures. Commercial banks in Romania have different approaches of showing the disclosures of operational risk. Accordingly, they do not disclose the same types of information. Our study advice Romanian commercial banks to increase prevailing operational risk disclosure proceedings. The contribution of this paper is to highlight the Romanian commercial approaches of the operational risk disclosures.

  18. The dissemination and implementation of national asthma ...

    African Journals Online (AJOL)

    Asthma is an important chronic inflammatory disorder with significant morbidity and mortality in South Africa. The development of national asthma guidelines by the South African Thoracic Society and National Asthma Education Programme has been one approach to try and improve the quality of care. The impact of ...

  19. Breathing clean air is Są'áh Naagháí Bik'eh Hózhóó (SNBH): a culturally centred approach to understanding commercial smoke-free policy among the Diné (Navajo People).

    Science.gov (United States)

    Chief, Carmenlita; Sabo, Samantha; Clark, Hershel; Nez Henderson, Patricia; Yazzie, Alfred; Nahee, Jacqueline; Leischow, Scott J

    2016-10-01

    Indigenous worldviews and research approaches are fundamental to make meaning of complex health issues and increase the likelihood of identifying existing cultural protective factors that have contributed to the resilience and survival of Indigenous people worldwide. We describe the process for applying the Diné (Navajo) paradigm of Są'áh Naagháí Bik'eh Hózhóó (SNBH), a belief system that guides harmonious living, and demonstrate how the application of SNBH enhances understanding of Navajo principles for well-being. Specifically, we juxtapose this analysis with a conventional qualitative analysis to illuminate and interpret Diné perspectives on the health and economic impact of commercial secondhand smoke and smoke-free policy. Focus groups were conducted throughout Navajo Nation to assess the appeal and impact of several evidence-based messages regarding the health and economic impact of smoke-free policy. Diné perspectives have shifted away from family and cultural teachings considered protective of a smoke-free life, and struggle to balance the ethical and economics of respect for individual and collective rights to live and work in smoke-free environments. Indigenous-centred approaches to public health research and policy analysis contribute to understanding the cultural knowledge, practices and beliefs that are protective of the health and well-being of Indigenous people. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  20. Commercial Landing System

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Fisheries Statistics Division of the NOAA Fisheries has automated data summary programs that anyone can use to rapidly and easily summarize U.S. commercial...

  1. Commercial Manure Applicators

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — This layer represents the office location for Commercial Manure Services (CMS). They transport, handle, store or apply manure for a fee. The company must be licensed...

  2. NASA commercial programs

    Science.gov (United States)

    1990-01-01

    Highlights of NASA-sponsored and assisted commercial space activities of 1989 are presented. Industrial R and D in space, centers for the commercial development of space, and new cooperative agreements are addressed in the U.S. private sector in space section. In the building U.S. competitiveness through technology section, the following topics are presented: (1) technology utilization as a national priority; (2) an exploration of benefits; and (3) honoring Apollo-Era spinoffs. International and domestic R and D trends, and the space sector are discussed in the section on selected economic indicators. Other subjects included in this report are: (1) small business innovation; (2) budget highlights and trends; (3) commercial programs management; and (4) the commercial programs advisory committee.

  3. Commercial and Institutional Waste

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund; Fruergaard, Thilde

    2011-01-01

    Commercial and institutional waste is primarily from retail (stores), hotels, restaurants, health care (except health risk waste), banks, insurance companies, education, retirement homes, public services and transport. Within some of these sectors, e.g. retail and restaurants, large variations...

  4. MARKETING STRATEGY OF COMMERCIALIZATION OF INNOVATION

    Directory of Open Access Journals (Sweden)

    Savelyeva Irina Petrovna

    2013-04-01

    Full Text Available The purpose of the article is to develop an original approach to the formation of a marketing strategy of commercialization of innovations. The existing views on the process of creating marketing strategies were examined and classified and the algorithm of building marketing strategies for the processes commercialization of innovations was offered. The results can be used by industrial companies and in the educational process of marketing, strategic marketing and innovation management disciplines.

  5. EFFECTS OF COMMERCIAL CONTRACT

    OpenAIRE

    Ana-Maria Florea; Constantin Giurca

    2014-01-01

    The contract is a legal instrument used to organize economic and social life. International trade agreement has certain features in order to ensure the international exchange of goods and services between the Contracting Parties. In terms of commercial contract, there is a foreign origin element, that gives the parties the right to determine the law to govern the contract. A fundamental aspect of commercial contract, in addition to that of determining the law applicable to judicial report est...

  6. Technology Commercialization Program 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    This reference compilation describes the Technology Commercialization Program of the Department of Energy, Defense Programs. The compilation consists of two sections. Section 1, Plans and Procedures, describes the plans and procedures of the Defense Programs Technology Commercialization Program. The second section, Legislation and Policy, identifies legislation and policy related to the Program. The procedures for implementing statutory and regulatory requirements are evolving with time. This document will be periodically updated to reflect changes and new material.

  7. Environmental management technology demonstration and commercialization

    International Nuclear Information System (INIS)

    Daly, D.J.; Erickson, T.A.; Groenewold, G.H.

    1995-01-01

    The Energy ampersand Environmental Research Center (EERC), a contract-supported organization focused on technology research, development, demonstration, and commercialization (RDD ampersand C), is entering its second year of a Cooperative Agreement with the U.S. Department of Energy (DOE) Morgantown Energy Technology Center (METC) to facilitate the development, demonstration, and commercialization of innovative environmental management (EM) technologies in support of the activities of DOE's Office of Environmental Science and Technology (EM-50) under DOE's EM Program. This paper reviews the concept and approach of the program under the METC-EERC EM Cooperative Agreement and profiles the role the program is playing in the commercialization of five EM technologies

  8. Use of applied theatre in health research dissemination and data validation: a pilot study from South Africa

    Science.gov (United States)

    Stuttaford, Maria; Bryanston, Claudette; Hundt, Gillian Lewando; Connor, Myles; Thorogood, Margaret; Tollman, Steve

    2010-01-01

    This article reports on a pilot study of the use of applied theatre in the dissemination of health research findings and validation of data. The study took place in South Africa, as part of the Southern Africa Stroke Prevention Initiative (SASPI) and was based at the University/Medical Research Council Rural Public Health and Health Transitions Research Unit (also known as the Agincourt Unit). The aim of SASPI was to investigate the prevalence of stroke and understand the social context of stroke. It was decided to use an applied theatre approach for validating the data and disseminating findings from the anthropological component of the study. The pilot study found that applied theatre worked better in smaller community groups. It allowed data validation and it elicited ideas for future interventions resulting from the health research findings. Evaluation methods of the impact of applied theatre as a vehicle for the dissemination and communication of research findings require further development. PMID:16322042

  9. Acute disseminated candidiasis with skin lesions: a systematic review.

    Science.gov (United States)

    Guarana, M; Nucci, M

    2018-03-01

    Neutropenic patients developing acute disseminated candidiasis may present with skin lesions. To evaluate the epidemiology of acute disseminated candidiasis with skin lesions in neutropenic patients, taking into consideration changes caused by different prophylactic strategies. A systematic review of English-language articles found via PubMed (1963-2016) was performed. We asked the following questions: (a) What Candida species are more frequently involved in this syndrome? (b) Has antifungal prophylaxis changed the species causing skin lesions? (c) What are the typical patterns of skin lesions? (d) What is the frequency of skin lesions in neutropenic patients with candidaemia or acute disseminated candidiasis? (e) Has antifungal prophylaxis decreased the incidence of acute disseminated candidiasis with skin lesions? Among 183 studies, 33 were selected, reporting 100 cases of acute disseminated candidiasis with skin lesions in neutropenic patients. It occurred more frequently in the setting of induction therapy for de novo or relapsed acute leukaemia, and the most frequent Candida species were C. tropicalis (68%) and C. krusei (15%). Diffuse maculopapular lesions predominated in cases caused by C. tropicalis and nodular and papular lesions in cases caused by C. krusei. Prophylaxis with fluconazole was reported in six cases, C. krusei in five and C. ciferrii in one. The death rate was 45.4%. Two patterns were recognized: disseminated maculopapular lesions caused by C. tropicalis in patients not receiving fluconazole prophylaxis, occurring in 39% to 44% of neutropenic patients with acute disseminated candidiasis, and nodular lesions caused by C. krusei in patients receiving fluconazole prophylaxis, occurring less frequently. Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  10. Piloting a Commercial Model for Fortified Rice: Lessons Learned From Brazil.

    Science.gov (United States)

    Milani, Peiman; Spohrer, Rebecca; Garrett, Greg; Kreis, Katharine

    2016-05-18

    Two billion people worldwide have micronutrient deficiencies. Food fortification is a proven intervention to increase essential micronutrient availability in diets without requiring consumer behavioral change. Fortification of rice has high potential reach; however, cost, technology, market, and cultural constraints have prevented its wider adoption. From 2010 to 2014, PATH and Global Alliance for Improved Nutrition implemented a pilot project in Brazil testing a model to scale up rice fortification through commercial channels. The project focused on 5 areas: (1) building fortified rice kernel production capacity; (2) supply chain development; (3) distribution channel and market development; (4) demand generation; and (5) advocacy and knowledge dissemination. Primary data were collected in 2 rounds of quantitative research 6 months apart and conducted in 2 regions in Brazil. Secondary data were sourced from published literature, socioeconomic and demographic data, and sales figures from the project's rice miller partner. Postmortem analysis was conducted by the project team with input from external sources. Although the project successfully launched a fortified rice product and a category brand platform, it was unsuccessful in reaching meaningful scale. Market and industry dynamics affected producers' willingness to launch new fortified products. Consumers' strong attachment to rice combined with a weak understanding of micronutrient malnutrition hampered demand creation efforts. This project showed that a purely commercial approach is insufficient for sustainable scale-up of fortified rice to achieve public health goals in a 3- to 5-year period. © The Author(s) 2016.

  11. Commercial speech in crisis: Crisis Pregnancy Center regulations and definitions of commercial speech.

    Science.gov (United States)

    Gilbert, Kathryn E

    2013-02-01

    Recent attempts to regulate Crisis Pregnancy Centers, pseudoclinics that surreptitiously aim to dissuade pregnant women from choosing abortion, have confronted the thorny problem of how to define commercial speech. The Supreme Court has offered three potential answers to this definitional quandary. This Note uses the Crisis Pregnancy Center cases to demonstrate that courts should use one of these solutions, the factor-based approach of Bolger v. Youngs Drugs Products Corp., to define commercial speech in the Crisis Pregnancy Center cases and elsewhere. In principle and in application, the Bolger factor-based approach succeeds in structuring commercial speech analysis at the margins of the doctrine.

  12. Hardness variability in commercial technologies

    International Nuclear Information System (INIS)

    Shaneyfelt, M.R.; Winokur, P.S.; Meisenheimer, T.L.; Sexton, F.W.; Roeske, S.B.; Knoll, M.G.

    1994-01-01

    The radiation hardness of commercial Floating Gate 256K E 2 PROMs from a single diffusion lot was observed to vary between 5 to 25 krad(Si) when irradiated at a low dose rate of 64 mrad(Si)/s. Additional variations in E 2 PROM hardness were found to depend on bias condition and failure mode (i.e., inability to read or write the memory), as well as the foundry at which the part was manufactured. This variability is related to system requirements, and it is shown that hardness level and variability affect the allowable mode of operation for E 2 PROMs in space applications. The radiation hardness of commercial 1-Mbit CMOS SRAMs from Micron, Hitachi, and Sony irradiated at 147 rad(Si)/s was approximately 12, 13, and 19 krad(Si), respectively. These failure levels appear to be related to increases in leakage current during irradiation. Hardness of SRAMs from each manufacturer varied by less than 20%, but differences between manufacturers are significant. The Qualified Manufacturer's List approach to radiation hardness assurance is suggested as a way to reduce variability and to improve the hardness level of commercial technologies

  13. Diagnostic imaging pathways: development, dissemination, implementation, and evaluation.

    Science.gov (United States)

    Bairstow, Phillip James; Mendelson, Richard; Dhillon, Ravinder; Valton, Frederic

    2006-02-01

    There are signs of inappropriate application of medical imaging to diagnosis. Inappropriate imaging is a threat to effective diagnosis and effective allocation of resources. The development and deployment of knowledge-based clinical decision support systems is one strategy to reduce inappropriate imaging. DEVELOPMENT OF IMAGING PATHWAYS: A suite of 78 imaging pathways was conceived both as a decision support and educational tool. The pathways were drafted by imaging specialists, but further developed and modified, based on graded evidence and input from requesting clinicians. An electronic environment was developed to contain and deliver the pathways. DISSEMINATION AND IMPLEMENTATION: Imaging pathways were distributed via a hospital local area network and on compact disk. A multifaceted approach was used to raise general awareness of the pathways, followed by intensive 'marketing' activities. Two groups of clinicians were targeted; hospital-based clinicians and general practitioners. There was increased awareness of imaging pathways. Clinicians judged them to be useful for education and decision support. The method of electronic delivery was adequate. Knowledge of diagnostic imaging and requesting behaviour tended to become more aligned with the pathways. The central objective to reduce inappropriate medical imaging seems to be achievable. There is scope to improve the content and the electronic environment, achieve better integration into decision-making processes, and achieve better compliance. A linkage between imaging pathways and electronic requesting could provide alerts to 'non-compliant' requesting. The assignment of a higher cost, or a lower remuneration, to non-authorized and non-compliant imaging would provide tangible incentive to comply, unless there are compelling clinical contraindications.

  14. Dissemination of information on food irradiation

    International Nuclear Information System (INIS)

    Henon, Y.

    1986-09-01

    Information is unanimously recognised as the key to a wide acceptance of irradiated food. A case by case approach is necessary as the context may vary greatly from one country to another. Some actions that took place in the particular French situation are reported. The various targets are addressed and the theoretical product adoption process is described. In spite of several encouraging facts, it appears that a lot has yet to be done before any reliable conclusion on the acceptation or rejection of the process can be reached

  15. Mono or 3D video production for scientific dissemination of nuclear energy applications

    International Nuclear Information System (INIS)

    Freitas, Victor Goncalves G.; Mol, Antonio Carlos A.; Biermann, Bruna; Jorge, Carlos Alexandre F.; Araujo, Tawein

    2011-01-01

    This work presents results of educational videos development, mono or stereo, for scientific dissemination of nuclear energy applications. Nuclear energy span through many important applications for the society, ranging from electrical power generation to nuclear medicine, among others. Thus, the purpose is to disseminate this information for the general public and specially for students. Educational videos consist in a good approach for this purpose, due to the involvement of the public they provide, more than simply text or oral exposition, or even static images presentation. Stereo videos result in even more involvement of the public, besides immersion, the later due to the realism 3D views provide. The video developed in this work deals with explanations of electrical power generation, including nuclear reactor operation, shows the percentage of nuclear source as power generation all over the world, and explains also nuclear energy application in medicine. It is expected all these characteristics provided by the use of video or virtual reality techniques will achieve the purpose of disseminating such important information, regarding the benefits of nuclear energy to the society. (author)

  16. [The Ineq-Cities research project on urban health inequalities: knowledge dissemination and transfer in Spain].

    Science.gov (United States)

    Camprubí, Lluís; Díez, Èlia; Morrison, Joana; Borrell, Carme

    2014-01-01

    The Ineq-Cities project analyzed inequalities in mortality in small areas and described interventions to reduce inequalities in health in 16 European cities. This field note describes the dissemination of the project in Spain. In accordance with the recommendations of the project, the objective was to translate relevant results to key stakeholders - mainly technical staff, municipal officers and local social agents - and to provide an introduction to urban inequalities in health and strategies to address them. Twenty-four workshops were given, attended by more than 350 professionals from 92 municipalities. Knowledge dissemination consisted of the publication of a short book on inequalities in health and the approach to this problem in cities and three articles in nonspecialized media, a proposal for a municipal motion, and knowledge dissemination activities in social networks. Users rated these activities highly and stressed the need to systematize these products. This process may have contributed to the inclusion of health inequalities in the political agenda and to the training of officers to correct them. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  17. Mono or 3D video production for scientific dissemination of nuclear energy applications

    Energy Technology Data Exchange (ETDEWEB)

    Freitas, Victor Goncalves G.; Mol, Antonio Carlos A.; Biermann, Bruna; Jorge, Carlos Alexandre F., E-mail: mol@ien.gov.b, E-mail: vgoncalves@ien.gov.b, E-mail: calexandre@ien.gov.b [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Araujo, Tawein [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Escola de Belas Artes; Legey, Ana Paula [Universidade Gama Filho (UGF), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    This work presents results of educational videos development, mono or stereo, for scientific dissemination of nuclear energy applications. Nuclear energy span through many important applications for the society, ranging from electrical power generation to nuclear medicine, among others. Thus, the purpose is to disseminate this information for the general public and specially for students. Educational videos consist in a good approach for this purpose, due to the involvement of the public they provide, more than simply text or oral exposition, or even static images presentation. Stereo videos result in even more involvement of the public, besides immersion, the later due to the realism 3D views provide. The video developed in this work deals with explanations of electrical power generation, including nuclear reactor operation, shows the percentage of nuclear source as power generation all over the world, and explains also nuclear energy application in medicine. It is expected all these characteristics provided by the use of video or virtual reality techniques will achieve the purpose of disseminating such important information, regarding the benefits of nuclear energy to the society. (author)

  18. Dissemination of thermodynamic temperature above the freezing point of silver.

    Science.gov (United States)

    Sadli, M; Machin, G; Anhalt, K; Bourson, F; Briaudeau, S; del Campo, D; Diril, A; Kozlova, O; Lowe, D H; Mantilla Amor, J M; Martin, M J; McEvoy, H C; Ojanen-Saloranta, M; Pehlivan, Ö; Rougié, B; Salim, S G R

    2016-03-28

    The mise-en-pratique for the definition of the kelvin at high temperatures will formally allow dissemination of thermodynamic temperature either directly or mediated through high-temperature fixed points (HTFPs). In this paper, these two distinct dissemination methods are evaluated, namely source-based and detector-based. This was achieved by performing two distinct dissemination trials: one based on HTFPs, the other based on absolutely calibrated radiation thermometers or filter radiometers. These trials involved six national metrology institutes in Europe in the frame of the European Metrology Research Programme joint project 'Implementing the new kelvin' (InK). The results have shown that both dissemination routes are possible, with similar standard uncertainties of 1-2 K, over the range 1273-2773 K, showing that, depending on the facilities available in the laboratory, it will soon be possible to disseminate thermodynamic temperatures above 1273 K to users by either of the two methods with uncertainties comparable to the current temperature scale. © 2016 The Author(s).

  19. Pulmonary cryptococcosis: Clinical, radiographical and serological markers of dissemination.

    Science.gov (United States)

    Hung, Ming-Szu; Tsai, Ying-Huang; Lee, Cheng-Hui; Yang, Cheng-Ta

    2008-03-01

    This study aimed to identify markers of disseminated infection in patients presenting with pulmonary cryptococcosis. Patients diagnosed with pulmonary cryptococcosis at a tertiary hospital between April 1998 and April 2005 were included and their clinical, radiological and pathological data analysed retrospectively. Thirty-one patients (14 male) were recruited into the study. Disseminated infection was seen in nine patients (29%), with the isolation of Cryptococcus neoformans from the blood of five patients and the cerebrospinal fluid of seven (three patients had both positive blood and cerebrospinal fluid findings). Patients with disseminated infection had a significantly higher incidence of impaired cellular immunity (immunosuppressant use, AIDS and haematological malignancy) (P = 0.015), fever (P death (P = 0.04) when compared with patients with localized infection. Serum cryptococcal antigen (sCRAG) was positive in 17 of the 19 patients tested at the time of diagnosis. Significantly higher sCRAG titres were noted in patients who had fever (P = 0.001), interstitial abnormalities on CXR (P = 0.004), pleural effusion (P = 0.018), disseminated disease (P = 0.003) and in those who died (P = 0.05). In pulmonary cryptococcosis patients, the presence of fever, interstitial abnormalities on CXR or pleural effusion should lead clinicians to suspect disseminated infection. High titres of sCRAG may indicate more extensive extra-pulmonary involvement and a worse prognosis.

  20. Commercialization of animal biotechnology.

    Science.gov (United States)

    Faber, D C; Molina, J A; Ohlrichs, C L; Vander Zwaag, D F; Ferré, L B

    2003-01-01

    Commercialization of animal biotechnology is a wide-ranging topic for discussion. In this paper, we will attempt to review embryo transfer (ET) and related technologies that relate to food-producing mammals. A brief review of the history of advances in biotechnology will provide a glimpse to present and future applications. Commercialization of animal biotechnology is presently taking two pathways. The first application involves the use of animals for biomedical purposes. Very few companies have developed all of the core competencies and intellectual properties to complete the bridge from lab bench to product. The second pathway of application is for the production of animals used for food. Artificial insemination (AI), embryo transfer, in vitro fertilization (IVF), cloning, transgenics, and genomics all are components of the toolbox for present and future applications. Individually, these are powerful tools capable of providing significant improvements in productivity. Combinations of these technologies coupled with information systems and data analysis, will provide even more significant change in the next decade. Any strategies for the commercial application of animal biotechnology must include a careful review of regulatory and social concerns. Careful review of industry infrastructure is also important. Our colleagues in plant biotechnology have helped highlight some of these pitfalls and provide us with a retrospective review. In summary, today we have core competencies that provide a wealth of opportunities for the members of this society, commercial companies, producers, and the general population. Successful commercialization will benefit all of the above stakeholders. Copyright 2002 Elsevier Science Inc.

  1. Commercial Conspiracy Theories

    Directory of Open Access Journals (Sweden)

    Adrian eFurnham

    2013-06-01

    Full Text Available There are many ways to categorise conspiracy theories. In the present study, we examined individual and demographic predictors of beliefs in commercial conspiracy theories among a British sample of over 300 women and men. Results showed people were cynical and sceptical with regard to advertising tricks, as well as the tactics of organisations like banks and alcohol, drug and tobacco companies. Beliefs sorted into four identifiable clusters, labelled sneakiness, manipulative, change-the-rules and suppression/prevention. The high alpha for the overall scale suggested general beliefs in commercial conspiracy. Regressions suggested that those people who were less religious, more left-wing, more pessimistic, less (self-defined as wealthy, less Neurotic and less Open-to-Experience believed there was more commercial conspiracy. Overall the individual difference variables explained relatively little of the variance in these beliefs.The implications of these findings for the literature on conspiracy theories are discussed.

  2. Commercial Parts Technology Qualification Processes

    Science.gov (United States)

    Cooper, Mark S.

    2013-01-01

    Many high-reliability systems, including space systems, use selected commercial parts (including Plastic Encapsulated Microelectronics or PEMs) for unique functionality, small size, low weight, high mechanical shock resistance, and other factors. Predominantly this usage is subjected to certain 100% tests (typically called screens) and certain destructive tests usually (but not always) performed on the flight lot (typically called qualification tests). Frequently used approaches include those documented in EEE-INST-002 and JPL DocID62212 (which are sometimes modified by the particular aerospace space systems manufacturer). In this study, approaches from these documents and several space systems manufacturers are compared to approaches from a launch systems manufacturer (SpaceX), an implantable medical electronics manufacturer (Medtronics), and a high-reliability transport system process (automotive systems). In the conclusions section, these processes are outlined for all of these cases and presented in tabular form. Then some simple comparisons are made. In this introduction section, the PEM technology qualification process is described, as documented in EEE-INST-002 (written by the Goddard Space Flight Center, GSFC), as well as the somewhat modified approach employed at the Jet Propulsion Laboratory (JPL). Approaches used at several major NASA contractors are also described

  3. Ultrasound Presentation of a Disseminated Fetal and Neonatal Rhabdoid Tumor

    Directory of Open Access Journals (Sweden)

    Yolaine Joueidi

    2018-01-01

    Full Text Available This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. The mother consulted for a decrease in fetal movement. Fetal ultrasound showed signs of a disseminated tumor affecting the left armpit, liver, spleen, and limbs. A caesarian section was performed because of signs of fetal distress. Immunohistochemical analysis of a fetal biopsy showed deletion of the SMARCB1 gene. Pathological analysis of the placenta showed a rhabdoid tumor invading both fetal and maternal compartments. The mother underwent a whole-body MRI, and no metastasis was found. To the best of our knowledge, this is the first report of a disseminated rhabdoid tumor invading both fetal and maternal compartments.

  4. Limited dissemination of the wastewater treatment plant core resistome

    Science.gov (United States)

    Munck, Christian; Albertsen, Mads; Telke, Amar; Ellabaan, Mostafa; Nielsen, Per Halkjær; Sommer, Morten O. A.

    2015-01-01

    Horizontal gene transfer is a major contributor to the evolution of bacterial genomes and can facilitate the dissemination of antibiotic resistance genes between environmental reservoirs and potential pathogens. Wastewater treatment plants (WWTPs) are believed to play a central role in the dissemination of antibiotic resistance genes. However, the contribution of the dominant members of the WWTP resistome to resistance in human pathogens remains poorly understood. Here we use a combination of metagenomic functional selections and comprehensive metagenomic sequencing to uncover the dominant genes of the WWTP resistome. We find that this core resistome is unique to the WWTP environment, with WWTP environment. Our data highlight that, despite an abundance of functional resistance genes within WWTPs, only few genes are found in other environments, suggesting that the overall dissemination of the WWTP resistome is comparable to that of the soil resistome. PMID:26419330

  5. Imaging spectrum in disseminated histoplasmosis: case report and brief review

    International Nuclear Information System (INIS)

    Grover, S.B.; Midha, N.; Gupta, M.; Sharma, U.; Talib, V.H.

    2005-01-01

    The clinical manifestations of chronic disseminated histoplasmosis are non-specific and resemble those of other chronic infections and malignancies. We report the radiographic, sonographic and contrast-enhanced CT appearances of histoplasmosis in an adult male with non-insulin dependent diabetes mellitus, who was HIV negative and presented with weight loss and pyrexia. Imaging studies simulated tuberculosis with mediastinal lymphadenopathy, bilateral fibrotic lung lesions, hepatomegaly and bilateral hypoattenuating adrenal enlargement, without clinical or laboratory evidence of hypoadrenalism. Computed tomography-guided fine-needle aspiration biopsy of adrenal glands revealed Histoplasma capsulatum. We report our experience to increase awareness of the imaging spectrum of disseminated histoplasmosis and its similarity to tuberculosis as, with increasing incidence of AIDS, the chances of these infections are likely to increase. Moreover, awareness of this entity is important because it is known that untreated disseminated histoplasmosis is fatal Copyright (2005) Blackwell Publishing Asia Pty Ltd

  6. Disseminating online tools for building capacity among community practitioners.

    Science.gov (United States)

    Holt, Christina M; Fawcett, Stephen B; Schultz, Jerry A; Jones, Jami A; Berkowitz, Bill; Wolff, Thomas J; Francisco, Vincent T; Rabinowitz, Philip W

    2013-01-01

    To prepare the workforce for building healthier communities, we need to assure capabilities of a diverse and geographically distributed community of practitioners. Although the Internet is used extensively to disseminate practice information, less is known about the relative impact of various strategies for promoting its use. This empirical case study examines implementation of dissemination strategies and their association with increased user sessions in the online Community Tool Box (CTB), a widely used resource for community building. Dissemination activities included social media efforts, eNewsletters, search engine optimization efforts, partnering with other Web sites, and implementing a global Out of the Box Prize. Results suggest that increased user sessions were associated with search optimization and "mashups" delivering CTB content through partners' Web sites. The report concludes with a discussion of challenges and opportunities in promoting widespread use of capacity-building tools among those working to improve their communities.

  7. Study of information dissemination by satellite, volume 1

    Science.gov (United States)

    Connell, S.; Champness, B. G.; Stapley, B.; Winsbury, R.

    1985-05-01

    Western European demand for satellite information dissemination in the late 1990's was assessed. The major market opportunity lies in intra-organizational video communications. Broadcast satellites could be used to facilitate dispersal of newspaper printing sites and the development of regionalized or local editions. Examples would include the publication of editions of north European newspapers in Mediterranean holiday resorts. Data broadcasting services could use VBI or full channel teletext or other formats. The most promising area for data dissemination by satellite is the aggregation of a number of services which are themselves small, but in total could generate substantial demand. Examples of such services include dissemination of private company data to dispersed branches (pricing, stock levels, etc.).

  8. Commercial incineration demonstration

    International Nuclear Information System (INIS)

    Vavruska, J.S.; Borduin, L.C.

    1982-01-01

    Low-level radioactive wastes (LLW) generated by nuclear utilities presently are shipped to commercial burial grounds for disposal. Increasing transportation and disposal costs have caused industry to consider incineration as a cost-effective means of volume reduction of combustible LLW. Repeated inquiries from the nuclear industry regarding the applicability of the Los Alamos controlled air incineration (CAI) design led the DOE to initiate a commercial demonstration program in FY-1980. Development studies and results in support of this program involving ion exchange resin incineration and fission/activation product distributions within the Los Alamos CAI are described

  9. Geotube: a network based framework for Goescience dissemination

    Science.gov (United States)

    Grieco, Giovanni; Porta, Marina; Merlini, Anna Elisabetta; Caironi, Valeria; Reggiori, Donatella

    2016-04-01

    Geotube is a project promoted by Il Geco cultural association for the dissemination of Geoscience education in schools by open multimedia environments. The approach is based on the following keystones: • A deep and permanent epistemological reflection supported by confrontation within the International Scientific Community • A close link with the territory • A local to global inductive approach to basic concepts in Geosciences • The construction of an open framework to stimulate creativity The project has been developed as an educational activity for secondary schools (11 to 18 years old students). It provides for the creation of a network of institutions to be involved in order to ensure the required diversified expertise. They can comprise: Universities, Natural Parks, Mountain Communities, Municipalities, schools, private companies working in the sector, and so on. A single project lasts for one school year (October to June) and requires 8-12 work hours at school, one or two half day or full day excursions and a final event of presentation of outputs. The possible outputs comprise a pdf or ppt guidebook, a script and a video completely shooted and edited by the students. The framework is open in order to adapt to the single class or workgroup needs, the level and type of school, the time available and different subjects in Geosciences. In the last two years the two parts of the project have been successfully tested separately, while the full project will be presented at schools in in its full form in April 2016, in collaboration with University of Milan, Campo dei Fiori Natural Park, Piambello Mountain Community and Cunardo Municipality. The production of geotube outputs has been tested in a high school for three consecutive years. Students produced scripts and videos on the following subjects: geologic hazards, volcanoes and earthquakes, and climate change. The excursions have been tested with two different high schools. Firstly two areas have been

  10. A MARC II-Based Program for Retrieval and Dissemination

    Directory of Open Access Journals (Sweden)

    Georg R. Mauerhoff

    1971-09-01

    Full Text Available Subscriptions to the Library of Congress' MARC tapes number approximately sixty. The uses to which the weekly tapes have been put have been minimal in the area of Selective Dissemination of lnformation (SDI and current awareness. This paper reviews work that has been performed on hatched retrieval/dissemination and provides a description of a highly flexible cooperative SDI system developed by the Library, University of Saskatchewan, and the National Science Library. The system will permit searching over all subject areas represented by the English language monographic literature on MARC.

  11. Ocular manifestation of disseminated Mycobacterium simiae infection in a cat.

    Science.gov (United States)

    Dietrich, U; Arnold, P; Guscetti, F; Pfyffer, G E; Spiess, B

    2003-03-01

    Disseminated mycobacterial disease was diagnosed in an eight-year-old domestic shorthaired cat, with involvement of the skin, lungs, lymph nodes and one eye. Mycobacterium simiae was cultured from skin biopsies on solid agar and in liquid media. This organism is known to cause pulmonary, cutaneous or disseminated infection in human patients with acquired immunodeficiency syndrome but has never been encountered as a pathogen in companion animals. Combination treatment with rifampicin, enrofloxacin and clarithromycin resulted in complete clinical remission within six months, with no side effects. No recurrence was observed in a 22-month follow-up period.

  12. Extremely refractory Kawasaki disease with disseminated intravascular coagulation.

    Science.gov (United States)

    Koh, Young Kwon; Lee, Jae Hee; Park, Yeong Bong

    2017-07-01

    Disseminated intravascular coagulation is a rare complication of Kawasaki disease and appears in Kawasaki disease patients. We report a case of refractory Kawasaki disease complicated with disseminated intravascular coagulation and giant coronary aneurysm. A 5-month-old boy presented with Kawasaki disease with coagulopathy. Although the coagulopathy improved after fresh-frozen plasma and antithrombin-III administration, the fever persisted despite two rounds of intravenous immunoglobulin, along with intravenous methylprednisolone pulse therapy and infliximab administration. Despite all efforts to treatment, the patient had giant coronary aneurysms and died suddenly.

  13. MRI in acute disseminated encephalomyelitis following Semple antirabies vaccine

    Energy Technology Data Exchange (ETDEWEB)

    Murthy, J.M.K. [Department of Neurology, Nizam`s Institute of Medical Sciences, Panjagutta, Hyderabad (India)

    1998-07-01

    I reviewed MRI findings in five patients with acute disseminated encephalomyelitis following vaccination with Semple antirabies vaccine. MRI in two patients with encephalitis features showed multiple white matter lesions in the cerebrum, cerebellar peduncles and brain stem. Two patients who had features of cord involvement showed signal alterations in the cord extending over a few segments. Asymptomatic lesions in the cerebrum were seen in two patients. In a patient with encephalomyelitis MRI 50 days later showed resolution of the lesions. The white matter lesions described were indistinguishable from those seen in acute disseminated encephalomyelitis following other infections. (orig.) With 3 figs., 1 tab., 26 refs.

  14. Recurrent thymoma with a pleural dissemination invading the intervertebral foramen.

    Science.gov (United States)

    Toba, Hiroaki; Kondo, Kazuya; Takizawa, Hiromitsu; Tangoku, Akira

    2009-05-01

    We report a rare case of recurrent thymoma with pleural dissemination invading the intervertebral foramen. A woman with Masaoka's stage IVa thymoma with myasthenia gravis (MG) underwent macroscopically complete resection. After 45 months, she developed back pain. Computed tomography (CT) of the chest demonstrated a mass in the right thoracic cavity invading the intervertebral foramen between thoracic vertebrae 10 and 11. She underwent complete resection of the tumor and postoperative radiotherapy. The resected specimen was histologically diagnosed as a pleural dissemination from thymoma. There has been no local recurrence.

  15. Abdominal alterations in disseminated paracoccidioidomycosis: computed tomography findings

    Energy Technology Data Exchange (ETDEWEB)

    Vermelho, Marli Batista Fernandes; Correia, Ademir Silva; Michailowsky, Tania Cibele de Almeida; Suzart, Elizete Kazumi Kuniyoshi; Ibanes, Aline Santos; Almeida, Lanamar Aparecida; Khoury, Zarifa; Barba, Mario Flores, E-mail: marlivermelho@globo.com [Instituto de Infectologia Emilio Ribas (IIER), Sao Paulo, SP (Brazil)

    2015-03-15

    Objective: to evaluate the incidence and spectrum of abdominal computed tomography imaging findings in patients with paracoccidioidomycosis. Materials and methods: retrospective analysis of abdominal computed tomography images of 26 patients with disseminated paracoccidioidomycosis. Results: abnormal abdominal tomographic findings were observed in 18 patients (69.2%), while no significant finding was observed in the other 8 (30.8%) patients. Conclusion: computed tomography has demonstrated to play a relevant role in the screening and detection of abdominal abnormalities in patients with disseminated paracoccidioidomycosis. (author)

  16. Getting poetic with data: Using poetry to disseminate the first-person voices of parents of children with a disability.

    Science.gov (United States)

    Carter, Bernie; Sanders, Caroline; Bray, Lucy

    2018-01-01

    This paper considers the limitations of traditional prose-based approaches to research dissemination and explores the potential merits and tensions in adopting a poetic approach to disseminate participants' experiences and perspectives. Drawing on our experience of using I-poetry to create first-person poems from our research data we discuss the attractiveness of the subjective, expressive and relational opportunities of poetry, and its ability to compress experience and create emotional connections and evoke emotion. We also reflect upon and discuss the limitations, challenges and criticisms of the use of research poetry, with a specific focus on the use of data poems and their value in disseminating research findings. Using poetry compelled us to think with our data differently and our poems have generated visceral responses from parents and professionals. Research poetry has value within academic and clinical worlds but its greatest potential perhaps lies in providing a means of disseminating research to the wider range of stakeholders. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  17. Disseminating Ambient Assisted Living in Rural Areas

    Directory of Open Access Journals (Sweden)

    Gerhard Leitner

    2014-07-01

    Full Text Available The smart home, ambient intelligence and ambient assisted living have been intensively researched for decades. Although rural areas are an important potential market, because they represent about 80% of the territory of the EU countries and around 125 million inhabitants, there is currently a lack of applicable AAL solutions. This paper discusses the theoretical foundations of AAL in rural areas. This discussion is underlined by the achievements of the empirical field study, Casa Vecchia, which has been carried out over a four-year period in a rural area in Austria. The major goal of Casa Vecchia was to evaluate the feasibility of a specific form of AAL for rural areas: bringing AAL technology to the homes of the elderly, rather than moving seniors to special-equipped care facilities. The Casa Vecchia project thoroughly investigated the possibilities, challenges and drawbacks of AAL related to this specific approach. The findings are promising and somewhat surprising and indicate that further technical, interactional and socio-psychological research is required to make AAL in rural areas reasonable in the future.

  18. Commercial Crew Medical Ops

    Science.gov (United States)

    Heinbaugh, Randall; Cole, Richard

    2016-01-01

    Provide commercial partners with: center insight into NASA spaceflight medical experience center; information relative to both nominal and emergency care of the astronaut crew at landing site center; a basis for developing and sharing expertise in space medical factors associated with returning crew.

  19. Commercial Baking. Final Report.

    Science.gov (United States)

    Booth, Nancy

    A project filmed three commercial baking videotapes for use by secondary and adult students in food service programs. The three topics were basic dinner rolls, bread making, and hard breads and rolls. Quick-rise dough recipes were developed, written down, and explained for use with the videotapes. A pretest, posttest, and student guide were…

  20. Automatic Commercial Permit Sets

    Energy Technology Data Exchange (ETDEWEB)

    Grana, Paul [Folsom Labs, Inc., San Francisco, CA (United States)

    2017-12-21

    Final report for Folsom Labs’ Solar Permit Generator project, which has successfully completed, resulting in the development and commercialization of a software toolkit within the cloud-based HelioScope software environment that enables solar engineers to automatically generate and manage draft documents for permit submission.

  1. Commercial applications of telemedicine

    Science.gov (United States)

    Natiello, Thomas A.

    1991-01-01

    Telemedicine Systems Corporation was established in 1976 and is a private commercial supplier of telemedicine systems. These systems are various combinations of communications and diagnostic technology, designed to allow the delivery of health care services to remote facilities. The technology and the health care services are paid for by the remote facilities, such as prisons.

  2. The 'Sydney Principles' for reducing the commercial promotion of foods and beverages to children.

    Science.gov (United States)

    Swinburn, Boyd; Sacks, Gary; Lobstein, Tim; Rigby, Neville; Baur, Louise A; Brownell, Kelly D; Gill, Tim; Seidell, Jaap; Kumanyika, Shiriki

    2008-09-01

    A set of seven principles (the 'Sydney Principles') was developed by an International Obesity Taskforce (IOTF) Working Group to guide action on changing food and beverage marketing practices that target children. The aim of the present communication is to present the Sydney Principles and report on feedback received from a global consultation (November 2006 to April 2007) on the Principles. The Principles state that actions to reduce marketing to children should: (i) support the rights of children; (ii) afford substantial protection to children; (iii) be statutory in nature; (iv) take a wide definition of commercial promotions; (v) guarantee commercial-free childhood settings; (vi) include cross-border media; and (vii) be evaluated, monitored and enforced. The draft principles were widely disseminated and 220 responses were received from professional and scientific associations, consumer bodies, industry bodies, health professionals and others. There was virtually universal agreement on the need to have a set of principles to guide action in this contentious area of marketing to children. Apart from industry opposition to the third principle calling for a statutory approach and several comments about the implementation challenges, there was strong support for each of the Sydney Principles. Feedback on two specific issues of contention related to the age range to which restrictions should apply (most nominating age 16 or 18 years) and the types of products to be included (31% nominating all products, 24% all food and beverages, and 45% energy-dense, nutrient-poor foods and beverages). The Sydney Principles, which took a children's rights-based approach, should be used to benchmark action to reduce marketing to children. The age definition for a child and the types of products which should have marketing restrictions may better suit a risk-based approach at this stage. The Sydney Principles should guide the formation of an International Code on Food and Beverage

  3. Comparing three knowledge communication strategies - Diffusion, Dissemination and Translation - through randomized controlled studies.

    Science.gov (United States)

    Lane, Joseph P; Stone, Vathsala I

    2015-01-01

    This paper describes a series of three randomized controlled case studies comparing the effectiveness of three strategies for communicating new research-based knowledge (Diffusion, Dissemination, Translation), to different Assistive Technology (AT) stakeholder groups. Pre and post intervention measures for level of knowledge use (unaware, aware, interested, using) via the LOKUS instrument, assessed the relative effectiveness of the three strategies. The latter two approaches were both more effective than diffusion but also equally effective. The results question the value added by tailoring research findings to specific audiences, and instead supports the critical yet neglected role for relevance in determining knowledge use by stakeholders.

  4. Role of lower half body irradiation (LHBI) in palliative treatment of disseminated skeletal metastases

    International Nuclear Information System (INIS)

    Vyas, R.K.; Baboo, H.A.; Suresh, P.

    1993-01-01

    Half body irradiation (HBI) is a new and simple approach for palliative radiotherapy of disseminated skeletal metastasis. It has very good palliative effect with manageable side effects when given as low dose rate treatment. 15 patients with wide spread bony secondaries were treated with Lower Half body Irradiation (LHBI) at a dose rate of 80-90 c Gy/min at our institute. Pain relief was observed in all patients. Of these 50% cases had significant relief of pain. Performance status improved and dependence on analgesic drugs had also reduced. (author). 6 refs., 3 tabs

  5. Lunar Commercial Mining Logistics

    Science.gov (United States)

    Kistler, Walter P.; Citron, Bob; Taylor, Thomas C.

    2008-01-01

    Innovative commercial logistics is required for supporting lunar resource recovery operations and assisting larger consortiums in lunar mining, base operations, camp consumables and the future commercial sales of propellant over the next 50 years. To assist in lowering overall development costs, ``reuse'' innovation is suggested in reusing modified LTS in-space hardware for use on the moon's surface, developing product lines for recovered gases, regolith construction materials, surface logistics services, and other services as they evolve, (Kistler, Citron and Taylor, 2005) Surface logistics architecture is designed to have sustainable growth over 50 years, financed by private sector partners and capable of cargo transportation in both directions in support of lunar development and resource recovery development. The author's perspective on the importance of logistics is based on five years experience at remote sites on Earth, where remote base supply chain logistics didn't always work, (Taylor, 1975a). The planning and control of the flow of goods and materials to and from the moon's surface may be the most complicated logistics challenges yet to be attempted. Affordability is tied to the innovation and ingenuity used to keep the transportation and surface operations costs as low as practical. Eleven innovations are proposed and discussed by an entrepreneurial commercial space startup team that has had success in introducing commercial space innovation and reducing the cost of space operations in the past. This logistics architecture offers NASA and other exploring nations a commercial alternative for non-essential cargo. Five transportation technologies and eleven surface innovations create the logistics transportation system discussed.

  6. Co-design, co-production, and dissemination of social-ecological knowledge to promote sustainability and resilience: urban experiences from the U.S

    Science.gov (United States)

    J. Morgan Grove; Rinku Roy Chowdhury; Daniel. Childers

    2015-01-01

    To promote sustainability and resilience, the role of co-design, co-production, and dissemination of social-ecological knowledge is of growing interest and importance. Although the antecedents for this approach are decades old, the integration of science and practice to advance sustainability and resilience is different from earlier approaches in several ways. In this...

  7. Consumer engagement and the development, evaluation and dissemination of evidence-based parenting programs

    Science.gov (United States)

    Sanders, Matthew R.; Kirby, James N.

    2013-01-01

    A consumer perspective can contribute much to enhancing the “ecological fit” of population level parenting interventions so they meet the needs of parents. This approach involves building relationships with consumer groups and soliciting consumer input into the relevance and acceptability of interventions, clarifying the enablers and barriers to engagement and involvement of parents, and clarifying variables that influence a parent’s program completion. The adoption of a more collaborative approach to working with consumers is important if meaningful population level change in the prevalence of serious social, emotional and behavioral problems in children and young people is to be achieved. Parents seeking assistance for their children’s behavior come from a diverse range of socioeconomic backgrounds, educational levels, cultures and languages. This paper examines consumer engagement strategies that can be employed throughout the process of program development, evaluation, training and dissemination and in “scaling up” the intervention. We argue that a multi-level public health approach to parenting intervention requires a strong consumer perspective to enable interventions to be more responsive to the preferences and needs of families and to ensure improved population reach of interventions. Examples from large scale dissemination trials are used to illustrate how consumer input can result in an increasingly differentiated suite of evidence-based parenting programs. PMID:22440062

  8. Consumer engagement and the development, evaluation, and dissemination of evidence-based parenting programs.

    Science.gov (United States)

    Sanders, Matthew R; Kirby, James N

    2012-06-01

    A consumer perspective can contribute much to enhancing the "ecological fit" of population-level parenting interventions so they meet the needs of parents. This approach involves building relationships with consumer groups and soliciting consumer input into the relevance and acceptability of interventions, clarifying the enablers and barriers to engagement and involvement of parents, and clarifying variables that influence a parent's program completion. The adoption of a more collaborative approach to working with consumers is important if meaningful population-level change in the prevalence of serious social, emotional, and behavioral problems in children and young people is to be achieved. Parents seeking assistance for their children's behavior come from a diverse range of socioeconomic backgrounds, educational levels, cultures, and languages. This paper examines consumer engagement strategies that can be employed throughout the process of program development, evaluation, training, and dissemination, and in "scaling up" the intervention. We argue that a multilevel public health approach to parenting intervention requires a strong consumer perspective to enable interventions to be more responsive to the preferences and needs of families and to ensure improved population reach of interventions. Examples from large-scale dissemination trials are used to illustrate how consumer input can result in an increasingly differentiated suite of evidence-based parenting programs. Copyright © 2011. Published by Elsevier Ltd.

  9. Remanence and survival of commercial yeast in different ecological niches of the vineyard.

    Science.gov (United States)

    Cordero-Bueso, Gustavo; Arroyo, Teresa; Serrano, Ana; Valero, Eva

    2011-08-01

    The use of commercial wine yeast strains as starters has been grown extensively over the past three decades. Wine yeasts are annually released in winery environments; however, little is known about the fate of these strains in the vineyard. To evaluate the industrial starter yeasts' ability to survive in nature and become part of the natural microbiota of musts, commercial yeast was disseminated voluntarily in an experimental vineyard in the Madrid region (Spain). A large sampling plan was devised over 3 years, including samples of grapes, leaves, bark and soil. The disseminated yeast was well represented in the vineyard during the first 8 months. After 2 years, the commercial yeast strain had not survived in the sprayed plants, but a residual population was found in plants situated 50 m east of the sprayed area. After 3 years, commercial yeast disseminated was not found in the sampled vineyard. Grapes and soil showed the highest number of yeasts isolated in the vegetative period, the bark being the main natural reservoir during the resting stages. The result of analysis of population variations from year to year indicated that permanent implantation of commercial strain (K1M) in the vineyard did not occur and its presence was limited in time. © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  10. Using the printed medium to disseminate information about ...

    African Journals Online (AJOL)

    Objective: The printed medium is a popular method to disseminate health information to the South African public. Reader-focused research indicates, however, that most printed health messages do not transfer information successfully to target audiences. As the first phase of an ongoing investigation into the provision of ...

  11. Opportunistic Beacon Networks: Information Dissemination via Wireless Network Identifiers

    NARCIS (Netherlands)

    Türkes, Okan; Scholten, Johan; Havinga, Paul J.M.

    2016-01-01

    This paper presents OBN, a universal opportunistic ad hoc networking model particularly intended for smart mobile devices. It enables fast and lightweight data dissemination in wireless community networks through the utilization of universally-available wireless network identifiers. As a ubiquitous

  12. Disseminated peritoneal leiomyomatosis: A case report and review ...

    African Journals Online (AJOL)

    Disseminated peritoneal leiomyomatosis (DPL) is a rare, mostly benign clinical condition where multiple smooth-muscle nodules or growths of various sizes of uterine origin implant on the abdominal, pelvic and peritoneal surface. The condition can occur spontaneously, or iatrogenically after surgical seeding. We present ...

  13. Hysterosalpingography and Risks of HIV Dissemination in Women ...

    African Journals Online (AJOL)

    Of the 707 HSGs carried of with sterilizable metallic cannula, contrast medium reflux into the pelvic veins was recorded in 133 (17.83%) cases, whereas this phenomenon was absent in instrumentation with disposable catheters. Venous intravasation during HSG procedure carries a risk of horizontal dissemination of HIV ...

  14. Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement

    DEFF Research Database (Denmark)

    Patsche, Cecilie Blenstrup; Svensson, Erik; Wejse, Christian

    2014-01-01

    Mycobacterium celatum is a rare cause of human infection, causing disseminated disease in immunosuppressed individuals. Infections localized to the lungs and the lymph nodes have also been reported in immunocompetent individuals. The existing literature on the subject is limited as are experiences...

  15. DISSEMINATE CYSTICERCOSIS. One-day treatment in a case

    Directory of Open Access Journals (Sweden)

    Mashiyi MK

    2004-01-01

    Full Text Available We report a patient presenting disseminated cysticercosis characterized by neurocysticercosis, subcutaneous, muscular, and cardiac cysticercosis treated with praziquantel during one day RESUMEN: Se comenta el caso de un paciente que presentó cisticercosis diseminada, caracterizada por neurocisticercosis, y cisticercosis subcutánea, muscular y cardiaca, tratada con praziquantel durante un dia.

  16. Indigenous Knowledge Dissemination and Use : A Discuss | Akinde ...

    African Journals Online (AJOL)

    The paper discusses the dissemination and use of indigenous knowledge. It highlighted the type and sources of indigenous knowledge in Nigeria. Means and tools for creating and exchanging indigenous knowledge, the likely situations under which indigenous knowledge could be used and how indigenous knowledge ...

  17. An unusual cystic appearance of disseminated low-grade gliomas

    Energy Technology Data Exchange (ETDEWEB)

    Huang, T.; Zimmerman, R.A. [Dept. of Radiology, Children' s Hospital of Philadelphia, PA (United States); Perilongo, G. [Dipt. di Pediatria, Univ. di Padova (Italy); Kaufman, B.A. [Dept. of Neurosurgery, St Louis Children' s Hospital, St Louis, MO (United States); Holden, K.R. [Division of Pediatric Neurology, Room 511, Children' s Hospital, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425-2232 (United States); Carollo, C. [Division of Neuroradiology, Regione Veneto, Azienda Ospedalieri di Padova, Universita di Padova, Via Giustiniani 3, 35 128 Padua (Italy); Kling Chong, W.K. [Dept. of Radiology, Great Ormond Street Hospital for Children, London (United Kingdom)

    2001-10-01

    We report five cases of pediatric disseminated low-grade gliomas of the brainstem or spinal cord that exhibited an unusual, cystic pattern. Leptomeningeal disease was present in three of these at diagnosis, and was detected shortly afterwards in the other two. Four patients are alive up to 5 years later, following minimal to no intervention, while one is dead. (orig.)

  18. Integrity and dissemination control in administrative applications through information designators

    NARCIS (Netherlands)

    Teepe, W.G.

    When more and more information sources are being linked, it seems that it becomes ever more easy to track individuals in ways that are not deemed appropriate. However, increased linking of information does not need to imply increased dissemination of privacy-sensitive information. We present a new

  19. 22 CFR 229.140 - Dissemination of policy.

    Science.gov (United States)

    2010-04-01

    ....140 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 229.140 Dissemination... secondary school students, employees, sources of referral of applicants for admission and employment, and...

  20. 22 CFR 146.140 - Dissemination of policy.

    Science.gov (United States)

    2010-04-01

    ....140 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 146.140 Dissemination... secondary school students, employees, sources of referral of applicants for admission and employment, and...

  1. Effects of environmental information dissemination and use on food ...

    African Journals Online (AJOL)

    The study examined the effects of Environmental Information Dissemination and use on Food Security in Gwagwalada Area Council. The objective of the study is to determine the type of environmental information available in Gwagwalada Area Council of FCT.A total number of fifty questionnaires were issued and forty five ...

  2. Access to the internet for knowledge dissemination: agricultural ...

    African Journals Online (AJOL)

    Access to agricultural information is a prerequisite for agricultural development. However, information on how agricultural scientists make use of the Internet to access agricultural information is limited. This study therefore investigated access to the Internet for knowledge dissemination by agricultural researchers in ...

  3. Achieving Data Utility Fairness in Periodic Dissemination for VANETs

    NARCIS (Netherlands)

    de Souza Schwartz, Ramon; Ohazulike, Anthony; Scholten, Johan; IEEE,

    In addition to safety, Vehicular Ad-hoc Networks (VANETs) enable the development of new information-rich applications that disseminate relevant data to vehicles. One key challenge in such networks is to use the available bandwidth efficiently when there is: (i) a short connectivity time due to the

  4. Social network and innovation dissemination among farmers in ...

    African Journals Online (AJOL)

    There is no adequate link between the farmers and the social groups which are very pivotal to the adoption of innovation and its eventual usage. This study therefore looked at social network and innovation dissemination among farmers in Kwara state Nigeria. This research specifically examined the impact of social network ...

  5. Neuroinvasion by Mycoplasma pneumoniae in Acute Disseminated Encephalomyelitis

    Science.gov (United States)

    Moschopulos, Michael; Hungerbuehler, Hansjoerg; Guarner, Jeannette; Genrich, Gillian L.; Zaki, Sherif R.

    2008-01-01

    We report the autopsy findings for a 45-year-old man with polyradiculoneuropathy and fatal acute disseminated encephalomyelitis after having Mycoplasma pneumoniae pneumonia. M. pneumoniae antigens were demonstrated by immunohistochemical analysis of brain tissue, indicating neuroinvasion as an additional pathogenetic mechanism in central neurologic complications of M. pneumoniae infection. PMID:18394283

  6. A residual cystic lesion in acute disseminated encephalomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Go, T. [Otsu Red Cross Hospital, Nagara (Japan). Dept. of Paediatrics; Imai, T. [Kyoto Univ. School of Medicine, Kyoto (Japan). Dept. of Paediatrics

    2000-09-01

    We report a case of acute disseminated encephalomyelitis (ADEM) with a residual cystic lesion on MRI. This seemed to be induced by Japanese encephalitis vaccination. Despite complete clinical improvement with high-dose steroid therapy, the cystic lesion has persisted for 3 years on MRI. There have been no previous reports of residual cystic lesions in ADEM. (orig.)

  7. Progressive disseminated histoplasmosis presenting with cachexia and hypercalcemia

    Directory of Open Access Journals (Sweden)

    Khasawneh FA

    2013-02-01

    Full Text Available Faisal A Khasawneh,1 Subhan Ahmed,2 Ruba A Halloush31Section of Infectious Diseases, Department of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, 2Section of Nephrology, Department of Internal Medicine, University of Oklahoma, Tulsa, OK, 3Amarillo Pathology Group, Amarillo, TX, USAAbstract: Histoplasmosis is a common endemic mycosis. The majority of infections involving this dimorphic fungus are asymptomatic. Manifestations in symptomatic patients are diverse, ranging from flu-like illness to a more serious disseminated disease. We present here a case of chronic disseminated histoplasmosis mimicking a metastatic cancer. We reviewed the literature for cases of disseminated histoplasmosis presenting with hypercalcemia, focusing particularly on clinical presentation, risk factors predisposing for fungal infection, and outcome. We report a case of a 65-year-old diabetic male who presented with unexplained weight loss and hypercalcemia. Multiple brain space-occupying lesions and bilateral adrenal enlargement were evident on imaging studies. Biopsies showed caseating granulomas with budding yeast, consistent with histoplasmosis. The patient's symptoms resolved after liposomal amphotericin B and itraconazole therapy. Granulomatous diseases, including fungal infections, should be considered alongside malignancies, in patients with similar presentation.Keywords: disseminated histoplasmosis, hypercalcemia

  8. The Role of Communication in Dissemination of Improved ...

    African Journals Online (AJOL)

    Most of the respondents do not understand the major language of instruction in Nigerian institutions due to absence of multilingualism in dissemination of techniques. Employment of more female extension agents, extension agents who can speak the farmers own language as well encouraging multilingualism will lead to ...

  9. Marketing: Exploring Applications for Educational Dissemination. Literature Synthesis.

    Science.gov (United States)

    Reed, Linda

    This synthesis of information about marketing and information dissemination of education-related products is divided into three parts: an overview of major writings, specific marketing strategies, and resources for further study. The first part opens with a definition of marketing as it relates to education. A review of the literature provides…

  10. Deliverable 9.7 - GALA Dissemination Report 4

    NARCIS (Netherlands)

    Westera, Wim; Berta, Riccardo; Moreno-Ger, Pablo; Bellotti, Francesco; Nadolski, Rob; Padrón-Nápoles, Carmen; Boyle, Liz; Beligan, Daniel; Baalsrud Hauge, Jannicke

    2014-01-01

    We have created and executed a separate plan for the transition of GALA to the Serious Games Society for securing the conditions in the post-project phase. For assessing the effectiveness of the dissemination efforts we have devised 5 outward- looking KPIs. All KPI requirements were met. Also,

  11. Disseminated intravascular coagulation in malaria: A case report ...

    African Journals Online (AJOL)

    Disseminated intravascular coagulation (DIC) is seen in <5% of patients with severe Plasmodium falciparum malaria and is more common in cerebral malaria. Here, we report the diagnosis and management of a case of severe P. falciparum malaria with DIC. Keywords: Cerebral malaria, cytokine storm, DIC, heparin ...

  12. Diffuse bony involvement in disseminated BCG disease in a patient ...

    African Journals Online (AJOL)

    BCG (bacille Calmette-Guérin) vaccination is carried out worldwide to prevent tuberculosis. It is considered to be very effective and has an excellent safety profile, but complications do occur. These may range from erythema and abscess at the site of inoculation to extensive disseminated disease including regional and ...

  13. A new way of dissemination in Anagallis arvensis L. (Primulaceae

    Directory of Open Access Journals (Sweden)

    Jacek Drobnik

    2011-01-01

    Full Text Available Anagallis arvensis L. fruits are globose pyxides. They contain a unique globose columella with 20-30 seeds on its surface. In ripe, open fruits the ball-shaped columella detaches easily and becomes a unique diaspore, which can roll on the ground. This way of dissemination has not been described so far neither in Anagallis nor in other Primulaceae.

  14. Youth Policies and Programmes. Strategies for Internationalization and Dissemination.

    Science.gov (United States)

    Van Oudenhoven, Nico; Wazir, Rekha

    This paper reviews the key issues and methodologies involved in the effort to internationalize youth policies and programs so that the exchange of information and experience could provide useful ideas for others. Related general processes of knowledge transfer and dissemination and the more specific strategies involved in replication and…

  15. Capacity of Community-Based Organisations to disseminate ...

    African Journals Online (AJOL)

    Objective: To assess the capacity of established community based organisations (CBOs) to disseminate information on sleeping sickness control. Design: Participatory interview process administered to randomly selected CBOs in a tsetse and trypanosomosis endemic area. Setting: Busia district, Western, Kenya. Results: ...

  16. Women's preference for folk/modern media in disseminating HIV ...

    African Journals Online (AJOL)

    This study investigated women's preference for folk/modern media in disseminating HIV/AIDS information in a rural community in Nigeria. Survey research design was employed in carrying out the study. A rural community was purposively selected in Oyo State, Nigeria. Snowball sampling technique was employed in ...

  17. An unusual cystic appearance of disseminated low-grade gliomas

    International Nuclear Information System (INIS)

    Huang, T.; Zimmerman, R.A.; Perilongo, G.; Kaufman, B.A.; Holden, K.R.; Carollo, C.; Kling Chong, W.K.

    2001-01-01

    We report five cases of pediatric disseminated low-grade gliomas of the brainstem or spinal cord that exhibited an unusual, cystic pattern. Leptomeningeal disease was present in three of these at diagnosis, and was detected shortly afterwards in the other two. Four patients are alive up to 5 years later, following minimal to no intervention, while one is dead. (orig.)

  18. Disseminated Cutaneous Leishmaniasis in HIV positive patient - A ...

    African Journals Online (AJOL)

    Disseminated cutaneous leishmaniasis and HIV dual-infection is seldom reported. Leishmaniasis and HIV co-infection may intensify the immune defect and is the chief reason for atypical presentation and widespread progression of cutaneous leishmaniasis and its defiance to conventional therapy. Here we report a ...

  19. Disseminated intravascular coagulation in meningococcal sepsis. Case 7

    NARCIS (Netherlands)

    Zeerleder, S.; Zürcher Zenklusen, R.; Hack, C. E.; Wuillemin, W. A.

    2003-01-01

    We report on a man (age: 49 years), who died from severe meningococcal sepsis with disseminated intravascular coagulation (DIC), multiple organ dysfunction syndrome and extended skin necrosis. We discuss in detail the pathophysiology of the activation of coagulation and fibrinolysis during sepsis.

  20. Dissemination of watershed management information through the World Wide Web

    Science.gov (United States)

    Malchus B. Baker; Deborah J. Young

    2000-01-01

    Information and related literature on watershed management practices is sometimes not widely known nor readily accessible. New electronic technologies provide unique tools for disseminating research findings to scientists, educators, land management professionals, and the public. This paper illustrates how the usefulness and accessibility of research information from...

  1. Documentation and dissemination of agricultural Research results in ...

    African Journals Online (AJOL)

    A study was conducted to find out the volume of documented vis a vis generated agricultural research information over a 10-year period and to identify existing avenues for disseminating generated research information to the target population. A questionnaire survey was conducted between December 1996 and February ...

  2. CT of disseminated plasmacytoma - in an AIDS patient

    Energy Technology Data Exchange (ETDEWEB)

    Leder, D.S.; Nazarian, L.N.; Burke, M. [Thomas Jefferson Univ., Philadelphia, PA (United States)

    1996-05-01

    It is well known that acquired immunodeficiency syndrome (AIDS) is associated with increased risk of neoplasms, particularly Kaposi sarcoma and non-Hodgkin lymphoma. There have been several recent reports in the literature describing plasma cell tumors in AIDS patients. We report the imaging findings in a case of widely disseminated plasmacytoma in a patient with known AIDS. 7 refs., 3 figs.

  3. Fluid Analysis of Network Content Dissemination and Cloud Systems

    Science.gov (United States)

    2017-03-06

    performance in complex network content dissemination and cloud systems . We employed tools of queueing theory, convex optimization and control theory, to...optimization problem, and solve it in cases of practical interest. Numerous insights on practical caching mechanisms result from this mathematical ...

  4. Dissemination of parasites by animal movements in small ruminant farms.

    Science.gov (United States)

    Vasileiou, N G C; Fthenakis, G C; Papadopoulos, E

    2015-09-30

    The present paper discusses the spread of parasites by animal movements in small ruminant farms; it focuses in dissemination of parasitic forms that would lead to subsequent infection of sheep or goats. Systems of small ruminant production involve a component of animal movement (e.g., grazing) as part of routine husbandry, which favors spread of parasitic forms; that refers mainly to parasites of the digestive system (nematodes, trematodes, cestodes, protozoa), as well as helminthes of the respiratory system, although dissemination of the various parasitic forms in the environment would not always result to subsequent infection; external parasites may also be disseminated during movements, e.g., to inhabit wooden poles used in fencing. New livestock into a farm constitutes a biosecurity hazard and the most common means to introducing new parasitic pathogens into a farm; in contemporary small ruminant health management, this contributes in dissemination of anthelmintic resistant parasitic strains; other parasitic disease agents (e.g., mange mites, ticks) may also be spread into a farm that way. Often, especially in small scale farming, visits of rams or bucks take place from one farm to another during the mating season; in such cases, ectoparasites (e.g., mange mites) can be disseminated through direct contact of animals, as well other pathogens (e.g., Toxoplasma gondii, Neospora caninum) via the semen. During transportation of sheep/goats, parasitic forms can also spread, as well as during movement of sheep or goats to slaughterhouses, in which case dogs present in these places would contribute to their dissemination. Spread of life forms of various parasites can also occur from animal species present in the environment of sheep or goats; these include animals present within a farm, stray dogs roaming around a farm (e.g., for spread of Multiceps multiceps, Echinococcus granulosus, Taenia hydatigena, N. caninum), cats commanding the environment of a farm (e.g., for

  5. Disseminating effective clinician communication techniques: Engaging clinicians to want to learn how to engage patients.

    Science.gov (United States)

    Pollak, Kathryn I; Back, Anthony L; Tulsky, James A

    2017-10-01

    Patient-clinician communication that promotes patient engagement enhances health care quality. Yet, disseminating effective communication interventions to practicing clinicians remains challenging. Current methods do not have large and sustainable effects. In this paper, we argue that both top-down approaches (mandated by institutions) should be coupled with bottom-up approaches that address clinician motivation, confidence, and barriers. We need to engage clinicians in the same way we ask them to engage patients - strategically and with empathy. We discuss potentially innovative strategies to integrate top-down and bottom-up approaches in ways that fit clinicians' busy schedules and can inform policy. Copyright © 2017. Published by Elsevier B.V.

  6. POPIN Working Group on Dissemination of Population Information: Report on the meeting held from 2 to 4 April 1984.

    Science.gov (United States)

    1984-12-01

    The objectives of this meeting were: to analyze the general dissemination strategy and functions of POPIN member organizations and assess the methods currently employed to identify users; to select publications or other information output and evaluate how they are being distributed and how procedures for the selective dissemination of information are developed; to develop guidelines for determining the potential audience and reader's interests; to discuss the methodology for maintaining a register of readers' interest; to develop guidelines for establishing linds with key press and broadcasting agencies to ensure rapid dissemination of information; to dientify media and organizations currently involved in the dissemination of population information; to document experience and provide recommendations for the utilization of innovative approaches to serve audiences; and to explore ways and means to meet the special needs of policy makers. Problem areas in population information dissemination were identified at the meeting as well as priority areas in meeting speical information needs of policy makers. Collection of information for dissemination is difficult, costly and time-consuming; there is a shortage of staff trained in the repackaging and dissemination of population information; the direct use of the mass media for information dissemination is still very limited; and financial resources are limited. Priority areas include: compilation of a calendar of events or meetings; conducting media surveys and inventories of population infromation centers and their services and compilation of results; resource development through product marketing and preparation of resource catalogues; and preparation of executive summaries highlighting policy implications to facilitate policy making. Recommendations include: promotion of training and technical assistance in population information activities by the POPIN Coordinating Unit; encouraging member organizations with relevant

  7. Maintenance considerations of the STARFIRE commercial tokamak

    International Nuclear Information System (INIS)

    Trachsel, C.A.; Zahn, H.S.; Field, R.E.; Stevens, H.C.

    1979-01-01

    This paper presents the maintenance approach, the commercial tokamak design features that enhance maintenance and preliminary repair time and required mean-time-between-failures for major subsystems. Reactor hall building and maintenance equipment requirements including hot cells, coil rewinding, and cranes are discussed

  8. Molecular and Cellular mechanisms of Shigella flexneri dissemination

    Directory of Open Access Journals (Sweden)

    Herve eAgaisse

    2016-03-01

    Full Text Available The intracellular pathogen Shigella flexneri is the causative agent of bacillary dysentery in humans. The disease is characterized by bacterial invasion of intestinal cells, dissemination within the colonic epithelium through direct spread from cell to cell, and massive inflammation of the intestinal mucosa. Here, we review the mechanisms supporting S. flexneri dissemination. The dissemination process primarily relies on actin assembly at the bacterial pole, which propels the pathogen throughout the cytosol of primary infected cells. Polar actin assembly is supported by polar expression of the bacterial autotransporter family member IcsA, which recruits the N-WASP/ARP2/3 actin assembly machinery. As motile bacteria encounter cell-cell contacts, they form plasma membrane protrusions that project into adjacent cells. In addition to the ARP2/3-dependent actin assembly machinery, protrusion formation relies on formins and myosins. The resolution of protrusions into vacuoles occurs through the collapse of the protrusion neck, leading to the formation of an intermediate membrane-bound compartment termed vacuole-like protrusions (VLPs. VLP formation requires tyrosine kinase and phosphoinositide signaling in protrusions, which relies on the integrity of the bacterial type 3 secretion system (T3SS. The T3SS is also required for escaping double membrane vacuoles through the activity of the T3SS translocases IpaB and IpaC, and the effector proteins VirA and IcsB. Numerous factors supporting envelope biogenesis contribute to IcsA exposure and maintenance at the bacterial pole, including LPS synthesis, membrane proteases, and periplasmic chaperones. Although less characterized, the assembly and function of the T3SS in the context of bacterial dissemination also relies on factors supporting envelope biogenesis. Finally, the dissemination process requires the adaptation of the pathogen to various cellular compartments through transcriptional and post

  9. Lung Dendritic Cells Facilitate Extrapulmonary Bacterial Dissemination during Pneumococcal Pneumonia

    Directory of Open Access Journals (Sweden)

    Alva eRosendahl

    2013-06-01

    Full Text Available Streptococcus pneumoniae is a leading cause of bacterial pneumonia worldwide. Given the critical role of dendritic cells (DCs in regulating and modulating the immune response to pathogens, we investigated here the role of DCs in S. pneumoniae lung infections. Using a well-established transgenic mouse line which allows the conditional transient depletion of DCs, we showed that ablation of DCs resulted in enhanced resistance to intranasal challenge with S. pneumoniae. DC-depleted mice exhibited delayed bacterial systemic dissemination, significantly reduced bacterial loads in the infected organs and lower levels of serum inflammatory mediators than non-depleted animals. The increased resistance of DC-depleted mice to S. pneumoniae was associated with a better capacity to restrict pneumococci extrapulmonary dissemination. Furthermore, we demonstrated that S. pneumoniae disseminated from the lungs into the regional lymph nodes in a cell-independent manner and that this direct way of dissemination was much more efficient in the presence of DCs. We also provide evidence that S. pneumoniae induces expression and activation of matrix metalloproteinase-9 (MMP-9 in cultured bone marrow-derived DCs. MMP-9 is a protease involved in the breakdown of extracellular matrix proteins and is critical for DC trafficking across extracellular matrix and basement membranes during the migration from the periphery to the lymph nodes. MMP-9 was also significantly up-regulated in the lungs of mice after intranasal infection with S. pneumoniae. Notably, the expression levels of MMP-9 in the infected lungs were significantly decreased after depletion of DCs suggesting the involvement of DCs in MMP-9 production during pneumococcal pneumonia. Thus, we propose that S. pneumoniae can exploit the DC-derived proteolysis to open tissue barriers thereby facilitating its own dissemination from the local site of infection.

  10. Nuove strategie di disseminazione e figure emergenti: gli innovation brokers + Beyond dissemination of research findings: innovation brokers as emerging figures in stimulating agricultural innovation

    OpenAIRE

    Klerkx, L.W.A.

    2012-01-01

    More and more it is recognised that innovation cannot be explained by a linear approach to innovation in which public sector agricultural research and extension delivers new technology in a pipeline configuration through a dissemination approach, but calls for systems approach in which innovation is the result of a process of networking, interactive learning and negotiation among a heterogeneous set of actors (Leeuwis, 2004; Röling, 2009). The systems approach recognises that agricultural inn...

  11. Quality issues in the market based dissemination of solar home systems

    Energy Technology Data Exchange (ETDEWEB)

    Lindner, Klara [MicroEnergy International, Berlin (Germany)

    2011-07-01

    In general, Photovoltaic systems are built to last and require little maintenance. However, field studies have revealed a high number of system failures, which are linked to a lack of quality assurance. This paper depicts problems that occur with solar home systems (SHS) disseminated on a market-based approach. The research methodology is based on three pillars: A literature review covers documented projects around the world dealing with solar home system dissemination. Expert practitioners drawn together in a workshop have shared valuable experiences, while a trip to rural Tanzania has been carried out to collect personal insights from the field. To facilitate continuous sharing of challenges between different stakeholders, common quality issues are grouped into four categories according to their cause: component quality, system integration, business model and framework conditions. While the solar component and the user are often initially blamed for system failure, it shows that difficulties arise at various levels of the SHS life cycle - this paper highlights focus problems within each stage. As a root, three underlying challenges are suggested: maladjusted systems, inadequate installations and a disorganized after-sales service. A possible instrument to assure better quality in this context is the enforcement of standards also in market-based SHS sales. Microfinance institutions are assumed as an important partner, because only clients with a functioning system are willing to repay the linked loan. As most of these institutions lack technical knowledge, they can only become an agent for their clients' wish for customer protection, if an independent facility certifies the system's functionality. The given recommendation is that a sustainable approach for solar home system dissemination should not attempt to increase the affordability by developing cheaper products but by fostering income-generating activities, which facilitate paying for good quality

  12. Dissemination of Drinking Water Contamination Data to Consumers: A Systematic Review of Impact on Consumer Behaviors

    Science.gov (United States)

    Lucas, Patricia J.; Cabral, Christie; Colford, John M.

    2011-01-01

    Background Drinking water contaminated by chemicals or pathogens is a major public health threat in the developing world. Responses to this threat often require water consumers (households or communities) to improve their own management or treatment of water. One approach hypothesized to increase such positive behaviors is increasing knowledge of the risks of unsafe water through the dissemination of water contamination data. This paper reviews the evidence for this approach in changing behavior and subsequent health outcomes. Methods/Principal Findings A systematic review was conducted for studies where results of tests for contaminants in drinking water were disseminated to populations whose water supply posed a known health risk. Studies of any design were included where data were available from a contemporaneous comparison or control group. Using multiple sources >14,000 documents were located. Six studies met inclusion criteria (four of arsenic contamination and two of microbiological contamination). Meta-analysis was not possible in most cases due to heterogeneity of outcomes and study designs. Outcomes included water quality, change of water source, treatment of water, knowledge of contamination, and urinary arsenic. Source switching was most frequently reported: of 5 reporting studies 4 report significantly higher rates of switching (26–72%) among those who received a positive test result and a pooled risk difference was calculate for 2 studies (RD = 0.43 [CI0.4.0–0.46] 6–12 months post intervention) suggesting 43% more of those with unsafe wells switched source compared to those with safe wells. Strength of evidence is low since the comparison is between non-equivalent groups. Two studies concerning fecal contamination reported non-significant increases in point-of-use water treatment. Conclusion Despite the publication of some large cohort studies and some encouraging results the evidence base to support dissemination of contamination data to

  13. Dissemination of drinking water contamination data to consumers: a systematic review of impact on consumer behaviors.

    Directory of Open Access Journals (Sweden)

    Patricia J Lucas

    Full Text Available Drinking water contaminated by chemicals or pathogens is a major public health threat in the developing world. Responses to this threat often require water consumers (households or communities to improve their own management or treatment of water. One approach hypothesized to increase such positive behaviors is increasing knowledge of the risks of unsafe water through the dissemination of water contamination data. This paper reviews the evidence for this approach in changing behavior and subsequent health outcomes.A systematic review was conducted for studies where results of tests for contaminants in drinking water were disseminated to populations whose water supply posed a known health risk. Studies of any design were included where data were available from a contemporaneous comparison or control group. Using multiple sources >14,000 documents were located. Six studies met inclusion criteria (four of arsenic contamination and two of microbiological contamination. Meta-analysis was not possible in most cases due to heterogeneity of outcomes and study designs. Outcomes included water quality, change of water source, treatment of water, knowledge of contamination, and urinary arsenic. Source switching was most frequently reported: of 5 reporting studies 4 report significantly higher rates of switching (26-72% among those who received a positive test result and a pooled risk difference was calculate for 2 studies (RD = 0.43 [CI0.4.0-0.46] 6-12 months post intervention suggesting 43% more of those with unsafe wells switched source compared to those with safe wells. Strength of evidence is low since the comparison is between non-equivalent groups. Two studies concerning fecal contamination reported non-significant increases in point-of-use water treatment.Despite the publication of some large cohort studies and some encouraging results the evidence base to support dissemination of contamination data to improve water management is currently

  14. Methanol commercial aviation fuel

    International Nuclear Information System (INIS)

    Price, R.O.

    1992-01-01

    Southern California's heavy reliance on petroleum-fueled transportation has resulted in significant air pollution problems within the south Coast Air Basin (Basin) which stem directly from this near total dependence on fossil fuels. To deal with this pressing issue, recently enacted state legislation has proposed mandatory introduction of clean alternative fuels into ground transportation fleets operating within this area. The commercial air transportation sector, however, also exerts a significant impact on regional air quality which may exceed emission gains achieved in the ground transportation sector. This paper addresses the potential, through the implementation of methanol as a commercial aviation fuel, to improve regional air quality within the Basin and the need to flight test and demonstrate methanol as an environmentally preferable fuel in aircraft turbine engines

  15. Dissemination of Cultural Norms and Values: Agent-Based Modeling

    Directory of Open Access Journals (Sweden)

    Denis Andreevich Degterev

    2016-12-01

    Full Text Available This article shows how agent-based modeling allows us to explore the mechanisms of the dissemination of cultural norms and values both within one country and in the whole world. In recent years, this type of simulation is particularly prevalent in the analysis of international relations, becoming more popular than the system dynamics and discrete event simulation. The use of agent-based modeling in the analysis of international relations is connected with the agent-structure problem in international relations. Structure and agents act as interdependent and dynamically changing in the process of interaction between entities. Agent-structure interaction could be modeled by means of the theory of complex adaptive systems with the use of agent-based modeling techniques. One of the first examples of the use of agent-based modeling in political science is a model of racial segregation T. Shellinga. On the basis of this model, the author shows how the change in behavioral patterns at micro-level impacts on the macro-level. Patterns are changing due to the dynamics of cultural norms and values, formed by mass-media and other social institutes. The author shows the main areas of modern application of agent-based modeling in international studies including the analysis of ethnic conflicts, the formation of international coalitions. Particular attention is paid to Robert Axelrod approach based on the use of genetic algorithms to the spread of cultural norms and values. Agent-based modeling shows how to how to create such conditions that the norms that originally are not shared by a significant part of the population, eventually spread everywhere. Practical application of these algorithms is shown by the author of the article on the example of the situation in Ukraine in 2015-2016. The article also reveals the mechanisms of international spread of cultural norms and values. The main think-tanks using agent-based modeling in international studies are

  16. Ambient-aware continuous care through semantic context dissemination.

    Science.gov (United States)

    Ongenae, Femke; Famaey, Jeroen; Verstichel, Stijn; De Zutter, Saar; Latré, Steven; Ackaert, Ann; Verhoeve, Piet; De Turck, Filip

    2014-12-04

    The ultimate ambient-intelligent care room contains numerous sensors and devices to monitor the patient, sense and adjust the environment and support the staff. This sensor-based approach results in a large amount of data, which can be processed by current and future applications, e.g., task management and alerting systems. Today, nurses are responsible for coordinating all these applications and supplied information, which reduces the added value and slows down the adoption rate.The aim of the presented research is the design of a pervasive and scalable framework that is able to optimize continuous care processes by intelligently reasoning on the large amount of heterogeneous care data. The developed Ontology-based Care Platform (OCarePlatform) consists of modular components that perform a specific reasoning task. Consequently, they can easily be replicated and distributed. Complex reasoning is achieved by combining the results of different components. To ensure that the components only receive information, which is of interest to them at that time, they are able to dynamically generate and register filter rules with a Semantic Communication Bus (SCB). This SCB semantically filters all the heterogeneous care data according to the registered rules by using a continuous care ontology. The SCB can be distributed and a cache can be employed to ensure scalability. A prototype implementation is presented consisting of a new-generation nurse call system supported by a localization and a home automation component. The amount of data that is filtered and the performance of the SCB are evaluated by testing the prototype in a living lab. The delay introduced by processing the filter rules is negligible when 10 or fewer rules are registered. The OCarePlatform allows disseminating relevant care data for the different applications and additionally supports composing complex applications from a set of smaller independent components. This way, the platform significantly reduces

  17. Commercial Jet Transport Crashworthiness

    Science.gov (United States)

    1982-04-01

    symmetrically or asymetrically located and may be applied to landing gear, engi e as, wings, and fuselage separately or in combination. BASIC...crashworthiness in general. Specific application of the guidelines to commercial aircraft has been asses3ed. Appendix D presents a detailed synthesis ...synthesized across the five volumes to integrate the information into one single abstract summary. This summary is a synthesis and critique of the U.S

  18. Commercialization of microfluidic devices.

    Science.gov (United States)

    Volpatti, Lisa R; Yetisen, Ali K

    2014-07-01

    Microfluidic devices offer automation and high-throughput screening, and operate at low volumes of consumables. Although microfluidics has the potential to reduce turnaround times and costs for analytical devices, particularly in medical, veterinary, and environmental sciences, this enabling technology has had limited diffusion into consumer products. This article analyzes the microfluidics market, identifies issues, and highlights successful commercialization strategies. Addressing niche markets and establishing compatibility with existing workflows will accelerate market penetration. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Commercial nuclear power 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This report presents historical data on commercial nuclear power in the United States, with projections of domestic nuclear capacity and generation through the year 2020. The report also gives country-specific projections of nuclear capacity and generation through the year 2010 for other countries in the world outside centrally planned economic areas (WOCA). Information is also presented regarding operable reactors and those under construction in countries with centrally planned economies. 39 tabs

  20. International Commercial Arbitration

    OpenAIRE

    Hlušička, Ondřej

    2011-01-01

    The purpose of my thesis is to analyse one of the most used type of extrajudicial procedures, the International commercial arbitration. The reason for my research is the progress and elevation of use of the arbitration and not only on international field. The thesis is composed of six chapters, each of them dealing with different aspects of Arbitration. Chapter One is introductory and defines basic terminology used in the thesis. The chapter is subdivided into two parts. Part One describes in...

  1. Commercializing Academic Research

    DEFF Research Database (Denmark)

    Czarnitzki, Dirk; Hussinger, Katrin; Schneider, Cédric

    2011-01-01

    The knowledge produced by academic scientists has been identified as a potential key driver of technological progress. Recent policies in Europe aim at increasing commercially orientated activities in academe. Based on a sample of German scientists across all fields of science, we investigate the......, a preliminary evaluation of the effects of the abolishment of the “professor privilege” (the German counterpart of the US Bayh-Dole Act) reveals that this legal disposition led to an acceleration of this apparent decline....

  2. Commercialization of nanotechnology.

    Science.gov (United States)

    Hobson, David W

    2009-01-01

    The emerging and potential commercial applications of nanotechnologies clearly have great potential to significantly advance and even potentially revolutionize various aspects of medical practice and medical product development. Nanotechnology is already touching upon many aspects of medicine, including drug delivery, diagnostic imaging, clinical diagnostics, nanomedicines, and the use of nanomaterials in medical devices. This technology is already having an impact; many products are on the market and a growing number is in the pipeline. Momentum is steadily building for the successful development of additional nanotech products to diagnose and treat disease; the most active areas of product development are drug delivery and in vivo imaging. Nanotechnology is also addressing many unmet needs in the pharmaceutical industry, including the reformulation of drugs to improve their bioavailability or toxicity profiles. The advancement of medical nanotechnology is expected to advance over at least three different generations or phases, beginning with the introduction of simple nanoparticulate and nanostructural improvements to current product and process types, then eventually moving on to nanoproducts and nanodevices that are limited only by the imagination and limits of the technology itself. This review looks at some recent developments in the commercialization of nanotechnology for various medical applications as well as general trends in the industry, and explores the nanotechnology industry that is involved in developing medical products and procedures with a view toward technology commercialization. (c) 2009 John Wiley & Sons, Inc.

  3. Mosquito-disseminated pyriproxyfen yields high breeding-site coverage and boosts juvenile mosquito mortality at the neighborhood scale.

    Science.gov (United States)

    Abad-Franch, Fernando; Zamora-Perea, Elvira; Ferraz, Gonçalo; Padilla-Torres, Samael D; Luz, Sérgio L B

    2015-04-01

    Mosquito-borne pathogens pose major public health challenges worldwide. With vaccines or effective drugs still unavailable for most such pathogens, disease prevention heavily relies on vector control. To date, however, mosquito control has proven difficult, with low breeding-site coverage during control campaigns identified as a major drawback. A novel tactic exploits the egg-laying behavior of mosquitoes to have them disseminate tiny particles of a potent larvicide, pyriproxyfen (PPF), from resting to breeding sites, thus improving coverage. This approach has yielded promising results at small spatial scales, but its wider applicability remains unclear. We conducted a four-month trial within a 20-month study to investigate mosquito-driven dissemination of PPF dust-particles from 100 'dissemination stations' (DSs) deployed in a 7-ha sub-area to surveillance dwellings and sentinel breeding sites (SBSs) distributed over an urban neighborhood of about 50 ha. We assessed the impact of the trial by measuring juvenile mosquito mortality and adult mosquito emergence in each SBS-month. Using data from 1,075 dwelling-months, 2,988 SBS-months, and 29,922 individual mosquitoes, we show that mosquito-disseminated PPF yielded high coverage of dwellings (up to 100%) and SBSs (up to 94.3%). Juvenile mosquito mortality in SBSs (about 4% at baseline) increased by over one order of magnitude during PPF dissemination (about 75%). This led to a >10-fold decrease of adult mosquito emergence from SBSs, from approximately 1,000-3,000 adults/month before to about 100 adults/month during PPF dissemination. By expanding breeding-site coverage and boosting juvenile mosquito mortality, a strategy based on mosquito-disseminated PPF has potential to substantially enhance mosquito control. Sharp declines in adult mosquito emergence can lower vector/host ratios, reducing the risk of disease outbreaks. This approach is a very promising complement to current and novel mosquito control strategies

  4. Successful Resuscitation of Maternal Cardiac Arrest With Disseminated Intravascular Coagulation Guided by Rotational Thromboelastometry and Transesophageal Echocardiography: A Case Report.

    Science.gov (United States)

    Brown, Hannah; Barrett, Helen L; Lee, Julie; Pincus, Jason M; Kimble, Rebecca M; Eley, Victoria A

    2017-10-26

    We present a case of maternal cardiac arrest during an elective cesarean delivery. Transesophageal echocardiography identified a large pulmonary artery mass, and guided resuscitation efforts. After return of spontaneous circulation, the patient developed disseminated intravascular coagulation with massive hemorrhage. Blood product selection and volume replacement were guided by rotational thromboelastometry and transesophageal echocardiography, respectively. Correction of coagulopathy was observed clinically and confirmed by rotational thromboelastometry. The patient fully recovered without neurological deficit.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  5. MARKETING STRATEGY OF COMMERCIALIZATION OF INNOVATION

    Directory of Open Access Journals (Sweden)

    Ирина Петровна Савельева

    2013-04-01

    Full Text Available The purpose of the article is to develop an original approach to the formation of a marketing strategy of commercialization of innovations. The existing views on the process of creating marketing strategies were examined and classified and the algorithm of building marketing strategies for the processes commercialization of innovations was offered. The results can be used by industrial companies and in the educational process of marketing, strategic marketing and innovation management disciplines.DOI: http://dx.doi.org/10.12731/2218-7405-2013-4-4

  6. Characterization of commercial building appliances. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Patel, R.F.; Teagan, P.W.; Dieckmann, J.T.

    1993-08-01

    This study focuses on ``other`` end-uses category. The purpose of this study was to determine the relative importance of energy end-use functions other than HVAC and lighting for commercial buildings, and to identify general avenues and approaches for energy use reduction. Specific energy consuming technologies addressed include non-HVAC and lighting technologies in commercial buildings with significant energy use to warrant detailed analyses. The end-uses include office equipment, refrigeration, water heating, cooking, vending machines, water coolers, laundry equipment and electronics other than office equipment. The building types include offices, retail, restaurants, schools, hospitals, hotels/motels, grocery stores, and warehouses.

  7. Electronic evaluation for video commercials by impression index.

    Science.gov (United States)

    Kong, Wanzeng; Zhao, Xinxin; Hu, Sanqing; Vecchiato, Giovanni; Babiloni, Fabio

    2013-12-01

    How to evaluate the effect of commercials is significantly important in neuromarketing. In this paper, we proposed an electronic way to evaluate the influence of video commercials on consumers by impression index. The impression index combines both the memorization and attention index during consumers observing video commercials by tracking the EEG activity. It extracts features from scalp EEG to evaluate the effectiveness of video commercials in terms of time-frequency-space domain. And, the general global field power was used as an impression index for evaluation of video commercial scenes as time series. Results of experiment demonstrate that the proposed approach is able to track variations of the cerebral activity related to cognitive task such as observing video commercials, and help to judge whether the scene in video commercials is impressive or not by EEG signals.

  8. Editorial opinion: public dissemination of raw turbulence data

    Science.gov (United States)

    Sillero, Juan A.; Jiménez, Javier

    2016-04-01

    Many of the papers in this issue deal with processing of pre-existing large-scale turbulence data. We argue here that there is a certain urgency to the discussion of whether raw data should be made publicly available within the turbulence community, and of which are the best procedures, technology and rules for possible dissemination. Besides expressing the personal opinion that such sharing would be advantageous for the field, the urgency mostly arises from the danger that funding agencies and other institutions would otherwise set standards without proper community input. The experience of the Madrid School of Aeronautics with the dissemination of numerical simulation results is briefly reviewed, including the present technological solutions and usage statistics.

  9. Concept of scientific wildlife conservation and its dissemination.

    Science.gov (United States)

    Zhou, Xue-Hong; Wan, Xiao-Tong; Jin, Yu-Hui; Zhang, Wei

    2016-09-18

    In recent years, wildlife conservation has attracted great public attention. However, substantial distinctions can be found in the prevailing concepts of wildlife conservation, particularly with the recent notion that emphasizes animal rights. Wildlife welfare and wildlife rights are not synonymous, with welfare more compatible with the reasonable and legal utilization of wildlife. The key to scientific wildlife conservation is the appropriate awareness and appreciation of the relationship between wildlife conservation and utilization and the theoretical basis of holism. Nevertheless, rational biases regarding the public's understanding of wildlife conservation and the spread of information via social media still exist. As such, expansion of the concept of scientific wildlife conservation requires the application of several measures. Wildlife conservation researchers should be regarded as the most important disseminators of scientifically-based information, with education in schools and universities of growing importance. Furthermore, the media should shoulder the social responsibility for the accurate dissemination of conservation information.

  10. Overcoming Legal Limitations in Disseminating Slovene Web Corpora

    Directory of Open Access Journals (Sweden)

    Tomaž Erjavec

    2016-09-01

    Full Text Available Web texts are becoming increasingly relevant sources of information, with web corpora useful for corpus linguistic studies and development of language technologies. Even though web texts are directly accessable, which substantially simplifies the collection procedure compilation of web corpora is still complex, time consuming and expensive. It is crucial that similar endeavours are not repeated, which is why it is necessary to make the created corpora easily and widely accessible both to researchers and a wider audience. While this is logistically and technically a straightforward procedure, legal constraints, such as copyright, privacy and terms of use severely hinder the dissemination of web corpora. This paper discusses legal conditions and actual practice in this area, gives an overview of current practices and proposes a range of mitigation measures on the example of the Janes corpus of Slovene user-generated content in order to ensure free and open dissemination of Slovene web corpora.

  11. Topology for efficient information dissemination in ad-hoc networking

    Science.gov (United States)

    Jennings, E.; Okino, C. M.

    2002-01-01

    In this paper, we explore the information dissemination problem in ad-hoc wirless networks. First, we analyze the probability of successful broadcast, assuming: the nodes are uniformly distributed, the available area has a lower bould relative to the total number of nodes, and there is zero knowledge of the overall topology of the network. By showing that the probability of such events is small, we are motivated to extract good graph topologies to minimize the overall transmissions. Three algorithms are used to generate topologies of the network with guaranteed connectivity. These are the minimum radius graph, the relative neighborhood graph and the minimum spanning tree. Our simulation shows that the relative neighborhood graph has certain good graph properties, which makes it suitable for efficient information dissemination.

  12. CASE REPORT: Disseminated Tuberculosis with Strongyloides stercoralis Infestation

    Directory of Open Access Journals (Sweden)

    Maya Patil

    2012-01-01

    Full Text Available Case History: We are presenting a case of seven year old male with disseminated tuberculosis and infection with Strongyloides stercoralis (S.stercoralis The patient had severe hypoproteinemia and anasarca. S.stercoralis is a helminthic infection. Infection is acquired by walking bare foot on contaminated soil. After infection the filariform larvae invade the venous circulation and reach the intestine via respiratory system. Hyperinfection with this parasite leads to steatorrhea, oedema of duodenum, protein losing enteropathy,especially in immunocompromised individual. The patient had disseminated tuberculosis leading to decreased immunity which made the patient susceptible to hyperinfection with strongyloides. The patient responded dramatically to Ivermectin and anti tuberculartreatment. Timely intervention with appropriate drugs may prove to be lifesaving in such condition.

  13. Mexican journals of educational research towards mainstream dissemination of science

    Directory of Open Access Journals (Sweden)

    Cabrera-Flores, Mayer

    2014-08-01

    Full Text Available The purpose of this study is to analyze the Electronic Journal of Educational Research (REDIE on its path towards the common manner of scientific dissemination. This research presents the evolution of Mexican policy with regards to the journals, the situation of the Educational Research Mexican journals, and its profundity relating to REDIE. In its evolution, there were three moments that stood out the most: the standardization of quality criteria, the digitalization and open access of the scientific journals, those that came together with REDIE like REDALYC and LATINDEX , and the individual initiatives of those journals that motivated the development of the scientific dissemination in Mexico. The investigation concludes with the realization of the necessity of achieving agreement on the efforts of various principal actors: governmental bodies, institutions, and academic communities.

  14. Withdrawal of immunosuppresive agents in the treatment of disseminated coccidioidomycosis.

    Science.gov (United States)

    Kaplan, J E; Zoschke, D; Kisch, A L

    1980-04-01

    Disseminated coccidioidomycosis is a systemic fungal infection that causes high mortality in the renal transplatn patient. Cell-mediated immunity, which appears to be the relevant host defense mechanism, is impaired by the immunosupressive agents used to prevent allograft rejection. In the case presented, immunosuppressive therapy was stopped as an adjunct to treatment of this infection. The patient has shown evidence of improvement, and his allograft has continued to function nine months after the withdrawal of immunosuppressive therapy and 18 months after the diagnosis. In vitro lymphocyte function studies indicate that the impairment in cell-mediated immunity detected prior to withdrawal of immunosuppressive therapy has persisted, probably accounting for allograft survival. Withdrawal of immunosuppressive therapy may prolong survival in renal transplant patients with disseminated coccidioidomycosis. Additionally, depression in cell-mediated immunity associated with the fungal infection itself may be sufficient to prevent allograft rejection in these patients.

  15. Tumour heterogeneity promotes collective invasion and cancer metastatic dissemination.

    Science.gov (United States)

    Hallou, Adrien; Jennings, Joel; Kabla, Alexandre J

    2017-08-01

    Heterogeneity within tumour cell populations is commonly observed in most cancers. However, its impact on metastatic dissemination, one of the primary determinants of the disease prognosis, remains poorly understood. Working with a simplified numerical model of tumour spheroids, we investigated the impact of mechanical heterogeneity on the onset of tumour invasion into surrounding tissues. Our work establishes a positive link between tumour heterogeneity and metastatic dissemination, and recapitulates a number of invasion patterns identified in vivo , such as multicellular finger-like protrusions. Two complementary mechanisms are at play in heterogeneous tumours. A small proportion of stronger cells are able to initiate and lead the escape of cells, while collective effects in the bulk of the tumour provide the coordination required to sustain the invasive process through multicellular streaming. This suggests that the multicellular dynamics observed during metastasis is a generic feature of mechanically heterogeneous cell populations and might rely on a limited and generic set of attributes.

  16. Disseminated tuberculosis of the central nervous system responsive to rifabutin.

    Science.gov (United States)

    Riva, M; Crippa, S; Di Palma, F; Gerini, A M; Soresi, E; Scoccia, S

    1990-04-01

    Multiple cerebral tuberculomas are now very rare. We report the case of a young man with an 8-month history of headache, febricula and abscess of the left tibiotarsal joint, which was found to contain mycobacterium tuberculosis. Chest X-rays revealed miliariform dissemination to both lungs while CT and MR brain scans revealed numerous small nodules, especially in the posterior cranial fossa. Despite anti-tuberculosis therapy the patient developed a right pyramidal hemisyndrome and intracranial hypertension. The inclusion of rifabutin in the treatment schedule was followed by rapid improvement and a year later the patient was in good health and free from cerebral and pulmonary lesions. The interest of the case lies in the multiplicity of sites of the TB process in a non immunodepressed patient, the dissemination to the CNS without meningeal involvement, the resistance to standard antimycobacterials and the swift response to rifabutin.

  17. Modelling information dissemination under privacy concerns in social media

    Science.gov (United States)

    Zhu, Hui; Huang, Cheng; Lu, Rongxing; Li, Hui

    2016-05-01

    Social media has recently become an important platform for users to share news, express views, and post messages. However, due to user privacy preservation in social media, many privacy setting tools are employed, which inevitably change the patterns and dynamics of information dissemination. In this study, a general stochastic model using dynamic evolution equations was introduced to illustrate how privacy concerns impact the process of information dissemination. Extensive simulations and analyzes involving the privacy settings of general users, privileged users, and pure observers were conducted on real-world networks, and the results demonstrated that user privacy settings affect information differently. Finally, we also studied the process of information diffusion analytically and numerically with different privacy settings using two classic networks.

  18. Disseminated Mycobacterium avium complex infection in an immunocompetent pregnant woman

    Directory of Open Access Journals (Sweden)

    Kim Woo

    2006-10-01

    Full Text Available Abstract Background Disseminated mycobacterium avium complex (MAC occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity. Case presentation A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further work-up demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen. Conclusion This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.

  19. [Disseminated mucormycosis in immunocompetent patients: A disease that also exists].

    Science.gov (United States)

    Pozo Laderas, Juan Carlos; Pontes Moreno, Antonio; Pozo Salido, Carmen; Robles Arista, Juan Carlos; Linares Sicilia, María José

    2015-01-01

    Mucormycosis is usually an acute angioinvasive infections, which leads to non-suppurative necrosis and significant tissue damage. It represents 1.6% of all the invasive fungal infections and predominates in immunosuppressed patients with risk factors. Incidence has been significantly increased even in immunocompetent patients. Due to finding a case of disseminated mucormycosis caused by Rhizomucor pusillus in a young immunocompetent patient, a systematic review was carried out of reported cases in PubMed of mucormycosis in immunocompetent adults according to the main anatomic locations, and especially in disseminated cases. A review of the main risk factors and pathogenicity, clinical manifestations, techniques of early diagnosis, current treatment options, and prognosis is presented. Taxonomy and classification of the genus Mucor has also been reviewed. Copyright © 2013 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

  20. Acute Disseminated Encephalomyelitis: Typical Radiologic Findings: Case Report

    International Nuclear Information System (INIS)

    Pulgarin R, Luis G; Posada A, Marcela; Sanchez M, Luisa C

    2011-01-01

    A 28-year-old female patient developed neurological symptoms after a classical episode of dengue. The physical examination reveled no fever, no neurological focalization, and an altered mental status (Glasgow 12/15). Magnetic resonance imaging confirmed the diagnosis of acute disseminated encephalomyelitis. The patient showed clinical improvement following treatment with steroids. Acute disseminated encephalomyelitis (ADEM) is classically described as a uniphasic syndrome occurring in association with systemic viral infection (parainfectious encephalomyelitis) or immunization or vaccination (post vaccination encephalomyelitis). Pathologically, there is perivascular inflammation, edema, and demyelination within the CNS. Clinically, patients present with rapidly progressing focal or multifocal neurologic dysfunction. The treatment for ADEM is targeted at suppressing inflammation in the brain through the use of anti-inflammatory drugs such as intravenous corticosteroids.

  1. Dissemination of information to General Practitioners: a questionnaire survey

    Directory of Open Access Journals (Sweden)

    Fortnum Heather

    2004-11-01

    Full Text Available Abstract Background Early identification of permanent hearing impairment in children enables appropriate intervention which reduces adverse developmental outcomes. The UK Government has introduced a universal hearing screening programme for neonates. All involved health professionals, including those in Primary Care, need to be aware of the service to enable them to offer appropriate support to their patients. A programme of information dissemination within Primary Care was therefore undertaken. The aim of the current study was to determine the extent to which the information had reached General Practitioners (GPs, the GPs' preferred mode of dissemination and the sources from which GPs accessed information Methods Postal questionnaire survey of a randomised sample of 1000 GPs in the Phase I pilot sites of the Neonatal Hearing Screening Programme (NHSP. Results Responses were received from 54.2% of the sample. Just under 50% of those responding had received information, 62.2% of respondents said they would like to receive more information and the preferred methods of dissemination were the written word and web-sites to allow access when needed. Few GPs perceive themselves to have a core role in the delivery of the NHSP and thence a need for knowledge in the subject. Many are keen to delegate detail to a third party, usually the health visitor, who has traditionally had responsibility for hearing screening. Conclusions Dissemination efforts for service developments of relevance to GPs should concentrate on advertising a website address via brief but memorable posted literature and/or articles in relevant journals and magazines. The website should be GP-friendly, and have a dedicated area for GPs including information of specific relevance and downloadable information sheets.

  2. Ultrasound, CT and MRI of ruptured and disseminated hydatid cysts

    International Nuclear Information System (INIS)

    Sinner, W.N. von

    1990-01-01

    Three cases of echinococcus granulosus with rupture of hydatid cysts and widespread abdominal, pelvic of pleural dissemination are described. Ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) allowed recognition of ruptured hydatid cysts. This assisted to come to an appropriate therapy and exclusion or confirmation of hydatid cysts elsewhere in the body. Ultrasound, CT and MRI are also important for follow-up, evaluation of therapeutic response and/or early diagnosis of recurrence. (author). 22 refs.; 3 figs

  3. Data dictionary and formatting standard for dissemination of geotechnical data

    Science.gov (United States)

    Benoit, J.; Bobbitt, J.I.; Ponti, D.J.; Shimel, S.A.; ,

    2004-01-01

    A pilot system for archiving and web dissemination of geotechnical data collected and stored by various agencies is currently under development. Part of the scope of this project, sponsored by the Consortium of Organizations for Strong-Motion Observation Systems (COSMOS) and by the Pacific Earthquake Engineering Research Center (PEER) Lifelines Program, is the development of a data dictionary and formatting standard. This paper presents the data model along with the basic structure of the data dictionary tables for this pilot system.

  4. Disseminated lymphoma presenting as acute thigh pain and renal failure.

    LENUS (Irish Health Repository)

    Brown, Catherine

    2009-01-01

    A 66-year-old diabetic man presented with severe right thigh swelling and pain together with acute renal failure. At autopsy, this was found to be due to disseminated high grade B cell lymphoma invading the psoas muscle and multiple organs, including the kidneys. The unique presentation of this case emphasizes the need for increased awareness of the variety of ways in which lymphoma can manifest itself.

  5. Disseminated histoplasmosis simulating miliary tuberculosis: a case report

    International Nuclear Information System (INIS)

    Tavares Junior, Wilson Campos; Madureira, Marcus Magalhaes; Andrade, Diego Correa de; Guimaraes, Silvana Mangeon Meireles; Queiroz, Leonardo Campos; Avila, Renata Eliane de; Lambertucci, Jose Roberto

    2005-01-01

    Histoplasmosis is a disease caused by inhalation of the fungus Histoplasma capsulatum. In rare cases the disease affects immunocompetent individuals. Disseminated and severe disease is seen in immunocompromised patients. We report a case of a 45 year old immunocompromised patient presenting with weight loss and abdominal pain. Chest x-ray and computerized tomography examinations showed interstitial infiltrate and diffuse micro nodules. The initial diagnosis was miliary tuberculosis. However, the definitive diagnosis of miliary histoplasmosis was made later on. (author)

  6. Abdominal alterations in disseminated paracoccidioidomycosis: computed tomography findings

    OpenAIRE

    Marli Batista Fernandes Vermelho; Ademir Silva Correia; Tânia Cibele de Almeida Michailowsky; Elizete Kazumi Kuniyoshi Suzart; Aline Santos Ibanês; Lanamar Aparecida Almeida; Zarifa Khoury; Mário Flores Barba

    2015-01-01

    Objective: To evaluate the incidence and spectrum of abdominal computed tomography imaging findings in patients with paracoccidioidomycosis. Materials and Methods: Retrospective analysis of abdominal computed tomography images of 26 patients with disseminated paracoccidioidomycosis. Results: Abnormal abdominal tomographic findings were observed in 18 patients (69.2%), while no significant finding was observed in the other 8 (30.8%) patients. Conclusion: Computed tomography has demonstrated to...

  7. Disseminated Bacillus Calmette-Guerin infections after intravesical therapy

    Directory of Open Access Journals (Sweden)

    I Gerogianni

    2014-01-01

    Full Text Available Intravesical instillation of Bacillus Calmette-Guerin (BCG is the treatment of choice for superficial bladder carcinoma. Disseminated BCG infection presenting as granulomatous hepatitis or pneumonitis is a very rare complication of this treatment. Here we report a case series of seven patients previously treated with BCG presenting with pneumonitis. In two of the cases, identification of Mycobacterium bovis was achieved with molecular methods.

  8. Self-disseminating vaccines for emerging infectious diseases

    OpenAIRE

    Murphy, Aisling A.; Redwood, Alec J.; Jarvis, Michael A.

    2015-01-01

    Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate of emerging infectious diseases from animals. The spate of recent infectious disease outbreaks, including Ebola virus disease and Middle East respiratory syndrome, emphasize the need for development of new innovative tools to manage these emerging diseases. Disseminating vacc...

  9. Disseminated Histoplasmosis with Oral Manifestation in an Immunocompetent Patient

    Science.gov (United States)

    Chatterjee, Aishwarya; Agarwal, Manoj; Mathur, Meetu; Mathur, Setu; Mallikarjun, R.; Banerjee, Subrata

    2017-01-01

    A case of disseminated histoplasmosis (DH) in a 60-year-old female patient is reported from Jaipur, Rajasthan, India. The patient presented with multiple papules on the skin surrounding the lips, face, torso, trunk, and back. She also complained of growth in the palate. Histoplasmosis was confirmed by biopsy and histopathology of skin and palatal lesions. This case report highlights the presenting features and occurrence of histoplasmosis in nonendemic region in India. PMID:28255468

  10. Disseminated Histoplasmosis in Early Human Immunodeficiency Virus Infection.

    Science.gov (United States)

    Bagla, Prabhava; Sarria, Juan C

    2017-03-01

    Early human immunodeficiency virus (HIV) infection leads to transient immunosuppression followed by a quasi-homeostatic state with slow progression towards AIDS. Histoplasmosis has never been reported in early HIV. We present a case of disseminated histoplasmosis with documented recent seroconversion and review the literature regarding other opportunistic infections in early HIV. Copyright © 2017 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  11. Ultrasound, CT and MRI of ruptured and disseminated hydatid cysts

    Energy Technology Data Exchange (ETDEWEB)

    Sinner, W.N. von (King Faisal Specialist Hospital and Research Centre, Riyadh (Saudi Arabia). Department of Radiology)

    Three cases of echinococcus granulosus with rupture of hydatid cysts and widespread abdominal, pelvic of pleural dissemination are described. Ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) allowed recognition of ruptured hydatid cysts. This assisted to come to an appropriate therapy and exclusion or confirmation of hydatid cysts elsewhere in the body. Ultrasound, CT and MRI are also important for follow-up, evaluation of therapeutic response and/or early diagnosis of recurrence. (author). 22 refs.; 3 figs.

  12. Disseminated peritoneal leiomyomatosis with malignant change, in a male

    DEFF Research Database (Denmark)

    Lausen, I; Jensen, O J; Andersen, E

    1990-01-01

    Disseminated peritoneal leiomyomatosis (DPL) is a rare disorder, characterized by the occurrence of multiple leiomyomas scattered throughout the peritoneal cavity. Until this report DPL had been observed only in women and there is only one previous case with malignant change. A case of DPL...... in a male, complicated by sarcomatous transformation is reported. DPL has a definite malignant potential; patients with the disease should be followed closely for signs of progression....

  13. Tailored radiotherapeutic strategies for disseminated uterine cervical cancer patients

    International Nuclear Information System (INIS)

    Im, Jung Ho; Yoon, Hong In; Kim, Sunghoon; Nam, Eun Ji; Kim, Sang Wun; Yim, Ga Won; Keum, Ki Chang; Kim, Young Tae; Kim, Gwi Eon; Kim, Yong Bae

    2015-01-01

    To investigate the role of radiotherapy (RT) in and to suggest radiotherapeutic strategies for patients presenting with disseminated cervical cancer. We retrospectively analyzed 50 patients diagnosed as the disseminated cervical cancer with distant lymph nodal or visceral organ metastasis between September 1980 and August 2012. Patients were divided into two subgroups according to visceral organ metastasis: 35 patients diagnosed with distant lymph node metastasis only (group A) and 15 patients with visceral organ metastasis (group B). All patients received external beam RT to the pelvis (median dose 45 Gy) and high-dose rate intracavitary RT (median dose 30 Gy). Thirty-nine patients (78%) received chemotherapy. Median follow-up time was 74 months. The 5-year pelvic control rate (PCR) was 85.8%, and the progression-free survival (PFS), and overall survival (OS) rates were 28.7%, and 36.2%, respectively. The major treatment failure was systemic progression (32 patients, 64%). The 5-year PCRs in groups A and B were 87.4% and 74.7%, respectively (p > 0.05). Meanwhile, PFS and OS rates for group A were significantly better than those for group B (35.3% vs. 13.3%, p = 0.010; and 46.3% vs. 13.3%, p = 0.009, respectively). Our data revealed considerable prognostic heterogeneity in disseminated cervical cancer. Even though a high PCR was achieved in patients treated with definitive RT, survival outcomes were dependent on progression of visceral organ metastasis. Therefore, personalized RT and chemotherapy treatment strategies according to the presence of visceral organ metastasis in disseminated cervical cancer patients may help improve clinical outcomes

  14. Macrophage Functions in Early Dissemination and Dormancy of Breast Cancer

    Science.gov (United States)

    2016-09-01

    situ (DCIS) in humans 48   and mammary intraepithelial neoplasia in mice) but dissemination occurs and early 49   DCCs show few genetic aberrations...5   defined as mammary intraepithelial neoplasia in mice (similar to DCIS in humans) 23. 82   This process depends on HER2-NFkB-mediated...101   breast cancer since these show slow progression from early lesions such as 102   hyperplasia and mammary intra-epithelial neoplasia (Fig.1A

  15. Disseminated Hemangiosarcoma in a Juvenile Rhesus Macaque (Macaca mulatta)

    OpenAIRE

    Beck, Amanda P; Gray, Stanton B; Chaffee, Beth K

    2016-01-01

    Hemangiosarcoma is a malignant tumor of vascular endothelial origin that is sporadically reported in rhesus macaques. This report describes the clinicopathologic features of a 1-y-old rhesus macaque with spontaneous disseminated hemangiosarcoma that originally presented as a focal cutaneous mass. Histopathologic examination of multiple tumor foci revealed regions in which the neoplastic cells formed diffuse sheets, as well as the well-defined vascular channels typically associated with hemang...

  16. Dissemination of Technology to Evaluate Healthy Food Incentive Programs.

    Science.gov (United States)

    Freedman, Darcy A; Hunt, Alan R; Merritt, Katie; Shon, En-Jung; Pike, Stephanie N

    2017-03-01

    Federal policy supports increased implementation of monetary incentive interventions for chronic disease prevention among low-income populations. This study describes how a Prevention Research Center, working with a dissemination partner, developed and distributed technology to support nationwide implementation and evaluation of healthy food incentive programming focused on Supplemental Nutrition Assistance Program recipients. FM Tracks, an iOS-based application and website, was developed to standardize evaluation methods for healthy food incentive program implementation at direct-to-consumer markets. This evaluation examined diffusion and adoption of the technology over 9 months (July 2015-March 2016). Data were analyzed in 2016. FM Tracks was disseminated to 273 markets affiliated with 37 regional networks in 18 states and Washington, DC. All markets adopted the sales transaction data collection feature, with nearly all recording at least one Supplemental Nutrition Assistance Program (99.3%) and healthy food incentive (97.1%) transaction. A total of 43,493 sales transactions were recorded. By the ninth month of technology dissemination, markets were entering individual sales transactions using the application (34.5%) and website (29.9%) and aggregated transactions via website (35.6%) at similar rates. Use of optional evaluation features like recording a customer ID with individual transactions increased successively with a low of 22.2% during the first month to a high of 69.2% in the ninth month. Systematic and widely used evaluation technology creates possibilities for pragmatic research embedded within ongoing, real-world implementation of food access interventions. Technology dissemination requires supportive technical assistance and continuous refinement that can be advanced through academic-practitioner partnerships. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  17. Disseminated lesions at presentation in patients with optic neuritis.

    OpenAIRE

    Ormerod, I E; McDonald, W I; du Boulay, G H; Kendall, B E; Moseley, I F; Halliday, A M; Kakigi, R; Kriss, A; Peringer, E

    1986-01-01

    Thirty five adults and two children with clinically isolated optic neuritis were examined by magnetic resonance imaging (MRI) to determine the presence of disseminated lesions within the brain at presentation and to compare these findings with the results of evoked potential studies. Of the adult patients, 61% showed lesions on the scans whereas the evoked potentials suggested the presence of lesions outside the visual system in 30%. MRI is a sensitive method for the demonstration of clinical...

  18. Commercial nuclear power 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This report presents the status at the end of 1989 and the outlook for commercial nuclear capacity and generation for all countries in the world with free market economies (FME). The report provides documentation of the US nuclear capacity and generation projections through 2030. The long-term projections of US nuclear capacity and generation are provided to the US Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) for use in estimating nuclear waste fund revenues and to aid in planning the disposal of nuclear waste. These projections also support the Energy Information Administration's annual report, Domestic Uranium Mining and Milling Industry: Viability Assessment, and are provided to the Organization for Economic Cooperation and Development. The foreign nuclear capacity projections are used by the DOE uranium enrichment program in assessing potential markets for future enrichment contracts. The two major sections of this report discuss US and foreign commercial nuclear power. The US section (Chapters 2 and 3) deals with (1) the status of nuclear power as of the end of 1989; (2) projections of nuclear capacity and generation at 5-year intervals from 1990 through 2030; and (3) a discussion of institutional and technical issues that affect nuclear power. The nuclear capacity projections are discussed in terms of two projection periods: the intermediate term through 2010 and the long term through 2030. A No New Orders case is presented for each of the projection periods, as well as Lower Reference and Upper Reference cases. 5 figs., 30 tabs

  19. Aerocapacitor commercialization plan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-12

    The purpose of the Power-One Aerocapacitor Commercialization Plan is to communicate to members of management and to all employees the overall objectives of the corporation. Power-One, Inc., has participated in a US Federal Government Technology Reinvestment Project (TRP), entitled {open_quotes}Advanced Power Conversion based on the Aerocapacitor{close_quotes}: the project is a group effort, with Lawrence Livermore National Labs, GenCorp/Aerojet, PolyStor Corp. (a start-up company), and Power-One forming the consortium. The expected resulting technology is the {open_quotes}Aerocapacitor{close_quotes}, which possesses much higher performance levels than the usual capacitors on the market today. Power-One hopes to incorporate the Aerocapacitor into some of its products, hence enhancing their performance, as well as market privately-labeled aerocapacitors through its distribution channels. This document describes the details of Power-One`s plan to bring to market and commercialize the Aerocapacitor and Aerocapacitor-based products. This plan was formulated while Power-One was part of the Oerocap project. It has since pulled out of this project. What is presented in this plan is the work which was developed prior to the business decision to terminate this work.

  20. Importance of mixed methods in pragmatic trials and dissemination and implementation research.

    Science.gov (United States)

    Albright, Karen; Gechter, Katherine; Kempe, Allison

    2013-01-01

    With increased attention to the importance of translating research to clinical practice and policy, recent years have seen a proliferation of particular types of research, including pragmatic trials and dissemination and implementation research. Such research seeks to understand how and why interventions function in real-world settings, as opposed to highly controlled settings involving conditions not likely to be repeated outside the research study. Because understanding the context in which interventions are implemented is imperative for effective pragmatic trials and dissemination and implementation research, the use of mixed methods is critical to understanding trial results and the success or failure of implementation efforts. This article discusses a number of dimensions of mixed methods research, utilizing at least one qualitative method and at least one quantitative method, that may be helpful when designing projects or preparing grant proposals. Although the strengths and emphases of qualitative and quantitative approaches differ substantially, methods may be combined in a variety of ways to achieve a deeper level of understanding than can be achieved by one method alone. However, researchers must understand when and how to integrate the data as well as the appropriate order, priority, and purpose of each method. The ability to demonstrate an understanding of the rationale for and benefits of mixed methods research is increasingly important in today's competitive funding environment, and many funding agencies now expect applicants to include mixed methods in proposals. The increasing demand for mixed methods research necessitates broader methodological training and deepened collaboration between medical, clinical, and social scientists. Although a number of challenges to conducting and disseminating mixed methods research remain, the potential for insight generated by such work is substantial. Copyright © 2013 Academic Pediatric Association. Published by

  1. Gastrointestinal dissemination and transmission of Staphylococcus aureus following bacteremia.

    Science.gov (United States)

    Kernbauer, Elisabeth; Maurer, Katie; Torres, Victor J; Shopsin, Bo; Cadwell, Ken

    2015-01-01

    Mutations that alter virulence and antibiotic susceptibility arise and persist during Staphylococcus aureus bacteremia. However, an experimental system demonstrating transmission following bacteremia has been lacking, and thus implications of within-host adaptation for between-host transmission are unknown. We report that S. aureus disseminates to the gastrointestinal tract of mice following intravenous injection and readily transmits to cohoused naive mice. Both intestinal dissemination and transmission were linked to the production of virulence factors based on gene deletion studies of the sae and agr two-component systems. Furthermore, antimicrobial selection for antibiotic-resistant S. aureus displaced susceptible S. aureus from the intestine of infected hosts, which led to the preferential transmission and dominance of antibiotic-resistant bacteria among cohoused untreated mice. These findings establish an animal model to investigate gastrointestinal dissemination and transmission of S. aureus and suggest that adaptation during the course of systemic infection has implications beyond the level of a single host. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  2. [Disseminated BCG infection in patients with urinary bladder carcinoma].

    Science.gov (United States)

    Korać, Milos; Milosević, Branko; Lavadinović, Lidija; Janjić, Aleksandar; Brmbolić, Branko

    2009-01-01

    Bacillus Calmette-Guërin--a live, attenuated strain of Mycobacterium bovis has been used in immunotherapy of patients with superficial urinary bladder carcinoma. Some patients develop complications after intravesical instillation of BCG: high temperature followed by hematuria or granulomatous prostatits, epidydimoorchitis, urethral obstruction, and less than 1% have a systemic disease followed by dissemination of bacteria into other organs. A 50-year-old man underwent transurethral resection of a bladder tumor. One month after the operation BCG intravesical installations were administered for three weeks. After the fourth installation, our patient developed high fever, fatigue, vomiting, dark urine, light stools, and jaundice. On admission he was jaundiced with a high fever, enlarged liver and spleen and laboratory findings which included high erythrocyte sedimentation rate, pancytopenia, elevated liver enzymes, especially alkaline phosphatase and aminotranspherases. The bone-marrow biopsy showed granulomatous inflamation suggesting mycobacterial spread in the bone marrow, liver and spleen and sepsis. The patient was initially treated with antituberculous therapy, but his state did not improve until corticosteroids were added to the antituberculous treatment regimen. Although dissemination of BCG is a rare complication of intravesical BCG treatment of the bladder carcinoma, it may result in prolonged fever and granulomatous inflamation of the liver, spleen, lungs, bone marrow and BCG sepsis. Antituberclous agents in combination with corticosteroids comprise the treatment of choice for disseminated BCG infection.

  3. Limited dissemination of the wastewater treatment plant core resistome

    DEFF Research Database (Denmark)

    Munck, Christian; Albertsen, Mads; Telke, Amar

    2015-01-01

    Horizontal gene transfer is a major contributor to the evolution of bacterial genomes and can facilitate the dissemination of antibiotic resistance genes between environmental reservoirs and potential pathogens. Wastewater treatment plants (WWTPs) are believed to play a central role in the dissem......Horizontal gene transfer is a major contributor to the evolution of bacterial genomes and can facilitate the dissemination of antibiotic resistance genes between environmental reservoirs and potential pathogens. Wastewater treatment plants (WWTPs) are believed to play a central role...... in the dissemination of antibiotic resistance genes. However, the contribution of the dominant members of the WWTP resistome to resistance in human pathogens remains poorly understood. Here we use a combination of metagenomic functional selections and comprehensive metagenomic sequencing to uncover the dominant genes...... of the WWTP resistome. We find that this core resistome is unique to the WWTP environment, with WWTP environment. Our data highlight that, despite an abundance of functional resistance genes within WWTPs, only few genes are found in other environments, suggesting...

  4. Disseminated intravascular coagulation and massive obstetric hemorrhage. Management dilemma.

    Science.gov (United States)

    Al-Nuaim, Lulu A; Mustafa, Mohamed S; Abdel Gader, Abdel Galil M

    2002-06-01

    The objective of this retrospective study is to reflect on our experience on an optimal management for major postpartum hemorrhage, which would prevent the occurrence and complications of disseminated intravascular coagulation and minimize maternal mortality and morbidity. Ten cases out of the 30,000 of total deliveries of severe obstetric hemorrhage associated with disseminated intravascular coagulation were studied. This study was carried out over a 7 year period, October 1988 through to September 1995, at the Obstetric Unit, King Khalid University Teaching Hospital, Riyadh, Kingdom of Saudi Arabia. All of the 10 women received packed red blood cells, 8 had fresh frozen plasma, and 6 received platelet transfusion. The 10 cases developed disseminated intravascular coagulation following medical and surgical management, all women needed hysterectomy, 4 subtotal, 6 total, and 5 women had relaparotomy and pelvic packing. Two had bladder injuries. There was no maternal death. An early resort to hysterectomy when conservative measures fail, will minimize maternal morbidity and mortality. In case of continuous bleeding after hysterectomy, pelvic packing proved to be effective.

  5. Disseminating Comparative Effectiveness Research Through Community-based Experiential Learning.

    Science.gov (United States)

    Hansen, Richard A; Williamson, Margaret; Stevenson, Lynn; Davis, Brandy R; Evans, R Lee

    2017-02-25

    Objectives. To launch and evaluate a comparative effectiveness research education and dissemination program as part of an introductory pharmacy practice experience (IPPE). Methods. First- through third-year PharmD students received training on comparative effectiveness research and disseminated printed educational materials to patients in the community who they were monitoring longitudinally (n=314). Students completed an assessment and initial visit documentation form at the first visit, and a follow-up assessment and documentation form at a subsequent visit. Results. Twenty-three diabetes patients, 29 acid-reflux patients, 30 osteoarthritis patients, and 50 hypertension patients received materials. Aside from the patient asking questions, which was the most common outcome (n=44), the program resulted in 38 additional actions, which included stopping, starting, or changing treatments or health behaviors, or having additional follow-up or diagnostic testing. Small but positive improvements in patient understanding, confidence, and self-efficacy were observed. Conclusions. Dissemination of comparative effectiveness research materials in an IPPE program demonstrated a positive trend in markers of informed decision-making.

  6. Education and dissemination strategies of photoactuation as a novel phenomenon

    Science.gov (United States)

    Campo, E. M.; Wenn, D.; Ramos, I.; Esteve, J.; Mamojka, B.; Terentjev, E. M.

    2011-10-01

    In the current information age, scientists and educators are urged to disseminate scientific findings in a prompt manner for increased public acceptance, later on, in the market place. Customer acceptance of highly novel technologies is an education-driven effort that requires attention early-on during the stage of technology development. Prompt attention is particularly needed in technologies where nanoparticles are employed, such as those being developed within the Nano- Optical Mechanical Systems (NOMS) project. Another driving force to disseminate photoactuation is to generate interest and curiosity amongst the K-12 population that could eventually lead to increased enrollment of students in the physical sciences. In this paper, we present a work plan for the dissemination of photoactuation to society at large; from K-12 to the general public. The work plan will be designed in accordance with the logic model, following indications of the National Academy of Sciences, and will include a proposal for evaluating translational research following a process marker model.

  7. Web-Based Dissemination System for the Trusted Computing Exemplar Project

    National Research Council Canada - National Science Library

    Kane, Douglas R., Jr

    2005-01-01

    Open dissemination of the Trusted Computing Exemplar (TCX) project is needed. This dissemination must include methods to provide secure web access to project material, integrity verification of data, and group-based access controls...

  8. Development of a new dispenser for microbiological control agents and evaluation of dissemination by bumblebees in greenhouse strawberries.

    Science.gov (United States)

    Mommaerts, Veerle; Put, Kurt; Vandeven, Jessica; Jans, Kris; Sterk, Guido; Hoffmann, Lucien; Smagghe, Guy

    2010-11-01

    To date, in modern agriculture, biological control strategies are increasingly becoming the preferred pest management approach. However, the success of microbiological control agents (MCAs) largely depends on efficient dissemination into the crop. The pollinator-and-vector technology employs pollinating insects like bees for a better dissemination. In this study, a new dispenser for bumblebee workers of Bombus terrestris L. was developed. Binab-T-vector and Prestop-Mix were used as two typical MCA products for dissemination. In a first series of experiments in the laboratory for optimisation, the newly developed dispenser was a two-way type dispenser, 20 cm long, with two rectangular compartments and different entrance and exit holes. In addition, the amounts of MCA loaded on the workers were 10 times higher with the new dispenser as compared with the side-by-side passageway (SSP) dispenser. Typically, the highest amounts were recovered from the thorax and legs of the workers. In a second series of experiments under greenhouse conditions with the use of queen-right B. terrestris hives, successful dissemination in strawberry flowers was obtained at different distances from the hive (0-8 m, 8-18 m and 18-21 m), and the workers inoculated the first, second and third flowers that were consecutively visited. In addition, the new dispenser caused no adverse effects on worker foraging intensity, whereas a dramatic reduction was scored with an SSP dispenser. Finally, the data suggested that it is necessary to refill the newly developed dispenser at 3 day intervals. The results demonstrated that, with the use of the newly developed dispenser, bumblebee workers carried high amounts of MCA, and this resulted in a successful dissemination of MCA into strawberry flowers. Copyright © 2010 Society of Chemical Industry.

  9. Digital/Commercial (In)visibility

    DEFF Research Database (Denmark)

    Leander, Anna

    2017-01-01

    an argument demonstrating specifically how digital and commercial logics characterize the aesthetic, circulatory, and infrastructuring practices re-producing the regime of (in)visibility. It shows that digital/commercial logics are at the heart of the combinatorial marketing of multiple, contradictory images......This article explores one aspect of digital politics, the politics of videos and more spe- cifically of DAESH recruitment videos. It proposes a practice theoretical approach to the politics of DAESH recruitment videos focused on the re-production of regimes of (in)visibility. The article develops...... on the internet. The theoretical and political cost of overlooking these digital and commercial characteristics of DAESH visibility practices are high. It perpetuates misconceptions of how the videos work and what their politics are and it reinforces the digital Orientalism/Occidentalism in which...

  10. Development and Dissemination of the El Centro Health Disparities Measures Library.

    Science.gov (United States)

    Mitrani, Victoria Behar; O'Day, Joanne E; Norris, Timothy B; Adebayo, Oluwamuyiwa Winifred

    2017-09-01

    This report describes the development and dissemination of a library of English measures, with Spanish translations, on constructs relevant to social determinants of health and behavioral health outcomes. The El Centro Measures Library is a product of the Center of Excellence for Health Disparities Research: El Centro, a program funded by the National Institute on Minority Health and Health Disparities of the U.S. National Institutes of Health. The library is aimed at enhancing capacity for minority health and health disparities research, particularly for Hispanics living in the United States and abroad. The open-access library of measures (available through www.miami.edu/sonhs/measureslibrary) contains brief descriptions of each measure, scoring information (where available), links to related peer-reviewed articles, and measure items in both languages. Links to measure websites where commercially available measures can be purchased are included, as is contact information for measures that require author permission. Links to several other measures libraries are hosted on the library website. Other researchers may contribute to the library. El Centro investigators began the library by electing to use a common set of measures across studies to assess demographic information, culture-related variables, proximal outcomes of interest, and major outcomes. The collection was expanded to include other health disparity research studies. In 2012, a formal process was developed to organize, expand, and centralize the library in preparation for a gradual process of dissemination to the national and international community of researchers. The library currently contains 61 measures encompassing 12 categories of constructs. Thus far, the library has been accessed 8,883 times (unique page views as generated by Google Analytics), and responses from constituencies of users and measure authors have been favorable. With the paucity of availability and accessibility of translated

  11. Drug use disorders among long distance commercial vehicle drivers ...

    African Journals Online (AJOL)

    Substance use disorder occur among long distance commercial vehicle drivers, and there is a need to develop a system that identifies substance use disorders and provides treatment for drug users as part of a holistic approach against drugged-driving. Keywords: Drug-use disorders, long-distance commercial drivers, ...

  12. DETERMINATION OF PARASITE DRAG FOR COMMERCIAL AIRPLANE AT TRANSONIC SPEEDS

    OpenAIRE

    V. I. Shevyakov

    2014-01-01

    It considers the task of determination of parasite drag for subsonic commercial airplane on the base of theoretical calculation procedures. It contains the procedure for clarification of empirical approach to calculation of parasite drag at high speeds. It provides examples of calculation of parasite drag at transonic speeds as a result of step behind the slat on the wing of commercial airplane.

  13. DisseminACTION: disseminating science in the information age (www.action-euproject.eu: a website for researchers and parents)

    OpenAIRE

    Matteo Mauri

    2015-01-01

    www.action-euproject.eu is a website designed at the University of Cagliari, by the Department of Surgery, Faculty of Medicine, within the project “ACTION – Aggression in Children: unravelling gene-environment interplay to inform Treatment and InterventiON strategies”, a collaborative project which includes twelve international partners, funded under the 7th Framework Programme for Research, technological Development and Demonstration.Its aim is to properly disseminate official news, events, ...

  14. The Science, and Art, of Program Dissemination: Strategies, Successes, and Challenges

    Science.gov (United States)

    McCoy, Kathleen P.

    2015-01-01

    The purpose of this special issue is to provide readers with a greater awareness of the processes involved in dissemination, as well as existing supports that help disseminate and sustain evidence-based interventions. Although dissemination research is limited in most disciplines, it is particularly lacking in the social science field. Many…

  15. Disseminated Histoplasmosis in a 13-year-old girl: A case report ...

    African Journals Online (AJOL)

    Background: Disseminated histoplasmosis is a rare fungal infection and most documented cases are in immunecompromised individuals such as those with acquired immuno-deficiency syndrome. Objective: To describe a case of disseminated histoplasmosis in an adolescent girl. Method: We report a case of disseminated ...

  16. 75 FR 75207 - Regulation SBSR-Reporting and Dissemination of Security-Based Swap Information

    Science.gov (United States)

    2010-12-02

    ... Dissemination of Security-Based Swap Information; Proposed Rule #0;#0;Federal Register / Vol. 75 , No. 231... Dissemination of Security-Based Swap Information AGENCY: Securities and Exchange Commission. ACTION: Proposed... SBSR--Reporting and Dissemination of Security-Based Swap Information (``Regulation SBSR'') under the...

  17. Year 2000 commercial issues

    International Nuclear Information System (INIS)

    Kratz, M.P.J.; Booth, R.T.

    1998-01-01

    This presentation focused on commercial aspects of the Y2K including: (1) special communication issues, (2) outsourcing transactions, (3) joint ventures and the significance for the oil and gas industry, and (4) contingency planning. Communication issues involve interaction with suppliers and vendors of critical systems, liability for Y2K communications (misrepresentation, defamation, promissory estoppel, statutory liability), securities disclosure (Canadian and US SEC requirements), protected communications, protection for Year 2000 statements. Outsourcing problems highlighted include resistance of suppliers to assume responsibility for Y2K problem remediation, factors which support and negate supplier responsibility, scope of suppliers' obligation, and warranties in respect of third party software. Regarding joint ventures, questions concerning limitations on liability, supply warranties, stand-by arrangements, stockpiling inventory, indemnities, confidentiality, operator compensation versus operator risk, and insurance were raised and addressed. Among contingency planning issues the questions of Y2K legal audit, and disclosure aspects of contingency planning were the featured concerns. figs

  18. Commercial Alcohols Inc

    International Nuclear Information System (INIS)

    Janes, M.

    1998-01-01

    The production of ethanol from corn, and the growth of ethanol production in Canada were discussed, along with the environmental advantages and the role it plays in supporting the rural economy. Commercial Alcohols Inc. is the largest ethanol producer in Canada. Its plant in Chatham, Ontario, which opened in December 1997, is one of the largest in the world. Since 1990, sales of ethanol have increased ten fold. Total sales exceed $100 million. The company has five plants in Canada which produce ethanol fuel, industrial alcohol, grain neutral spirits, packaged alcohol, distillers grains, and carbon dioxide for use in carbonization of beverages. Plans are underway for construction of a new plant in Varennes, Quebec. The company is also working with the Ukraine for development of an ethanol facility in that country. 3 figs

  19. Nanovate commercializing disruptive nanotechnologies

    CERN Document Server

    Anis, Mohab; Sarhan, Wesam; Elsemary, Mona

    2017-01-01

    This book introduces readers from diverse backgrounds to the principles underlying nanotechnology, from devices to systems, while also describing in detail how businesses can use nanotechnology to redesign their products and processes, in order to have a clear edge over their competition. The authors include 75 case studies, describing in a highly-accessible manner, real nanotechnology innovations from 15 different industrial sectors. For each case study, the technology or business challenges faced by the company are highlighted, the type of nanotechnology adopted is defined, and the eventual economic and social impact is described. Introduces fundamentals of nanotechnology and its applications in a highly-accessible manner Includes 75 case studies of commercializing nanotechnology from 15 industrial sectors, including Automotive, Consumer Electronics, and Renewable Energy Enables nanotechnology experts to learn simple and important business concepts to facilitate the transfer of science to the market Introdu...

  20. Precision machining commercialization

    International Nuclear Information System (INIS)

    1978-01-01

    To accelerate precision machining development so as to realize more of the potential savings within the next few years of known Department of Defense (DOD) part procurement, the Air Force Materials Laboratory (AFML) is sponsoring the Precision Machining Commercialization Project (PMC). PMC is part of the Tri-Service Precision Machine Tool Program of the DOD Manufacturing Technology Five-Year Plan. The technical resources supporting PMC are provided under sponsorship of the Department of Energy (DOE). The goal of PMC is to minimize precision machining development time and cost risk for interested vendors. PMC will do this by making available the high precision machining technology as developed in two DOE contractor facilities, the Lawrence Livermore Laboratory of the University of California and the Union Carbide Corporation, Nuclear Division, Y-12 Plant, at Oak Ridge, Tennessee